# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Glyco_hydro_47 PF01532.15 EIW65407.1 - 2.3e-69 234.2 0.0 3.1e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2587 PF10759.4 EIW65408.1 - 0.027 13.8 1.3 0.078 12.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2587) BUD22 PF09073.5 EIW65408.1 - 1.8 7.5 14.7 3 6.8 10.2 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EIW65408.1 - 5.5 4.7 6.5 8.3 4.1 4.5 1.2 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.22 EIW65409.1 - 7.7e-05 22.1 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MIP-T3 PF10243.4 EIW65411.1 - 0.005 15.3 0.5 0.005 15.3 0.4 2.2 1 1 1 2 2 2 1 Microtubule-binding protein MIP-T3 DUF2587 PF10759.4 EIW65411.1 - 0.037 13.4 0.1 0.094 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Solute_trans_a PF03619.11 EIW65413.1 - 8.8e-69 231.8 18.1 1.1e-68 231.5 12.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CDC27 PF09507.5 EIW65414.1 - 2.5e-16 59.9 15.2 2.7e-16 59.8 10.6 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF867 PF05908.6 EIW65414.1 - 0.079 12.0 0.1 0.093 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF867) Stm1_N PF09598.5 EIW65414.1 - 6.3 7.5 6.2 1.7 9.3 0.1 2.3 2 1 0 2 2 2 0 Stm1 OTU PF02338.14 EIW65415.1 - 2.8e-08 34.3 0.0 5.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EIW65415.1 - 0.02 14.2 0.0 3.1 7.0 0.1 2.2 1 1 1 2 2 2 0 Peptidase C65 Otubain gag-asp_proteas PF13975.1 EIW65416.1 - 4.8e-06 26.3 0.0 8.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EIW65416.1 - 7.1e-05 22.5 3.1 0.00014 21.6 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 EIW65416.1 - 9.6e-05 22.8 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_3 PF13917.1 EIW65416.1 - 0.00025 20.6 1.6 0.00065 19.3 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EIW65416.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_5 PF14787.1 EIW65416.1 - 0.37 10.3 3.9 0.38 10.2 1.6 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Periviscerokin PF08259.6 EIW65417.1 - 2.9e-06 26.6 12.2 2e+02 2.6 0.0 10.6 12 0 0 12 12 12 0 Periviscerokinin family NOT2_3_5 PF04153.13 EIW65417.1 - 0.00053 19.8 4.2 5.6 6.8 0.1 3.5 4 0 0 4 4 4 3 NOT2 / NOT3 / NOT5 family NADH_dh_m_C1 PF15088.1 EIW65417.1 - 0.0084 15.5 13.5 33 4.0 0.1 7.2 5 3 2 7 7 7 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial CfAFP PF05264.6 EIW65417.1 - 0.0099 15.6 1.1 43 3.8 0.0 3.8 4 0 0 4 4 4 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF1317 PF07026.6 EIW65417.1 - 0.026 14.3 6.3 5.8 6.8 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1317) DDE_1 PF03184.14 EIW65418.1 - 2e-25 89.2 0.0 2.3e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW65418.1 - 0.00016 21.4 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease tRNA-synt_1 PF00133.17 EIW65419.1 - 3.9e-155 517.2 0.0 4.6e-155 517.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIW65419.1 - 1.5e-24 86.4 0.1 3.3e-24 85.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIW65419.1 - 1.3e-22 80.0 0.2 3.1e-12 45.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EIW65419.1 - 0.00077 18.6 0.0 0.049 12.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EIW65419.1 - 0.0021 16.8 0.0 0.017 13.8 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (K) SH2 PF00017.19 EIW65422.1 - 1.4e-09 37.5 0.5 4.4 7.1 0.0 5.2 5 0 0 5 5 5 4 SH2 domain Periviscerokin PF08259.6 EIW65422.1 - 5.6e-05 22.6 7.8 29 5.1 0.0 7.9 8 0 0 8 8 8 0 Periviscerokinin family SH3_2 PF07653.12 EIW65422.1 - 0.015 14.7 1.2 1.4e+02 2.0 0.0 5.3 5 1 0 5 5 5 0 Variant SH3 domain CfAFP PF05264.6 EIW65422.1 - 0.037 13.7 0.2 3.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Choristoneura fumiferana antifreeze protein (CfAFP) Dicer_dimer PF03368.9 EIW65422.1 - 0.06 13.1 0.0 0.33 10.7 0.0 2.1 3 0 0 3 3 3 0 Dicer dimerisation domain DUF1317 PF07026.6 EIW65422.1 - 0.12 12.2 0.9 8.3 6.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1317) DUF3505 PF12013.3 EIW65423.1 - 6.4e-10 39.2 2.8 6.4e-10 39.2 1.9 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) TSC22 PF01166.13 EIW65423.1 - 0.69 9.9 3.4 3 7.8 1.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family CMV_1a PF12467.3 EIW65424.1 - 0.095 13.0 3.8 0.11 12.8 2.6 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family bact-PGI_C PF10432.4 EIW65424.1 - 0.1 12.3 0.6 0.15 11.7 0.4 1.2 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region ROKNT PF08067.6 EIW65424.1 - 0.13 12.1 0.3 0.13 12.1 0.2 1.9 2 0 0 2 2 2 0 ROKNT (NUC014) domain DUF4407 PF14362.1 EIW65424.1 - 3.1 6.6 6.0 3.6 6.4 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3807 PF12720.2 EIW65424.1 - 3.3 7.8 11.4 4.1 7.5 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Periviscerokin PF08259.6 EIW65426.1 - 0.002 17.9 0.3 61 4.1 0.0 4.4 4 0 0 4 4 4 0 Periviscerokinin family SH3_2 PF07653.12 EIW65426.1 - 0.028 13.8 0.1 22 4.6 0.0 3.2 3 0 0 3 3 3 0 Variant SH3 domain NADH_dh_m_C1 PF15088.1 EIW65426.1 - 0.14 11.7 0.6 23 4.6 0.1 2.7 2 1 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DUF2587 PF10759.4 EIW65427.1 - 0.0043 16.4 0.1 0.0095 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2587) TFIIA PF03153.8 EIW65429.1 - 0.21 11.4 62.4 0.42 10.4 42.9 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PCI PF01399.22 EIW65430.1 - 2.4e-10 40.6 0.0 5.9e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EIW65430.1 - 2.4e-05 23.7 0.0 4.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 DUF3117 PF11314.3 EIW65430.1 - 0.019 14.4 0.1 0.084 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3117) TPR_7 PF13176.1 EIW65430.1 - 0.12 12.2 0.8 7.3 6.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIW65430.1 - 0.18 11.7 1.3 0.75 9.7 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Nitr_red_assoc PF09655.5 EIW65435.1 - 0.17 12.2 0.4 1 9.6 0.0 2.3 3 0 0 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Asp_protease_2 PF13650.1 EIW65436.1 - 5.8e-06 26.7 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIW65436.1 - 0.0005 19.8 0.0 0.0029 17.4 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EIW65436.1 - 0.00082 19.1 2.2 0.0017 18.2 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.15 EIW65436.1 - 0.0047 16.8 0.0 0.014 15.2 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease eIF3g PF12353.3 EIW65436.1 - 0.0052 16.6 3.1 0.014 15.2 2.2 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.1 EIW65436.1 - 0.019 14.4 0.1 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.14 EIW65438.1 - 1.1e-40 139.0 0.0 1.7e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW65438.1 - 1.7e-09 37.3 0.0 4.3e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EIW65438.1 - 5e-05 22.7 0.0 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EIW65438.1 - 7.4e-05 22.6 0.1 0.0039 17.1 0.0 3.4 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EIW65438.1 - 0.0027 17.3 0.1 0.013 15.0 0.0 2.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.1 EIW65438.1 - 0.058 12.9 0.4 0.52 9.8 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain SieB PF14163.1 EIW65438.1 - 0.18 11.3 0.0 23 4.5 0.0 2.3 2 0 0 2 2 2 0 Superinfection exclusion protein B Arb1 PF09692.5 EIW65439.1 - 0.053 12.3 1.2 0.094 11.5 0.9 1.3 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Myb_DNA-bind_6 PF13921.1 EIW65439.1 - 0.072 13.1 0.0 1.8 8.7 0.0 2.6 1 1 0 2 2 2 0 Myb-like DNA-binding domain LNS2 PF08235.8 EIW65442.1 - 8.5e-68 226.8 0.0 1.4e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) NAD_binding_1 PF00175.16 EIW65442.1 - 2.8e-25 88.9 0.0 5.4e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Lipin_N PF04571.9 EIW65442.1 - 1.1e-24 86.2 0.0 2.2e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region FAD_binding_6 PF00970.19 EIW65442.1 - 5.9e-14 51.9 0.0 2.7e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EIW65442.1 - 0.0071 16.2 0.0 0.37 10.6 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Acid_phosphat_B PF03767.9 EIW65442.1 - 0.12 11.7 0.1 0.44 9.8 0.0 1.8 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Yip1 PF04893.12 EIW65443.1 - 0.00039 19.9 17.7 0.00069 19.1 12.3 1.4 1 1 0 1 1 1 1 Yip1 domain Ras PF00071.17 EIW65444.1 - 7.4e-57 191.2 0.2 9.5e-57 190.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW65444.1 - 2.1e-20 73.3 0.1 3.1e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW65444.1 - 6.7e-15 54.7 0.2 8.2e-15 54.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW65444.1 - 3e-06 26.8 0.1 1.4e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EIW65444.1 - 1.2e-05 24.6 0.1 2.4e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIW65444.1 - 2.8e-05 23.4 0.1 3.3e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIW65444.1 - 5.7e-05 23.0 0.1 8.4e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW65444.1 - 0.004 16.4 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 EIW65444.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EIW65444.1 - 0.073 13.2 0.0 1.1 9.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.4 EIW65444.1 - 0.097 12.1 0.5 0.57 9.6 0.3 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Es2 PF09751.4 EIW65447.1 - 4e-100 336.1 5.3 4.9e-100 335.8 3.7 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 IF4E PF01652.13 EIW65449.1 - 2.9e-47 160.2 0.0 3.8e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Neurensin PF14927.1 EIW65450.1 - 0.18 11.1 1.1 0.33 10.3 0.8 1.6 1 1 0 1 1 1 0 Neurensin DUF1049 PF06305.6 EIW65450.1 - 0.88 9.0 7.8 6.7 6.2 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Acyl_transf_3 PF01757.17 EIW65450.1 - 0.9 8.3 11.9 1.2 7.8 8.1 1.3 1 1 0 1 1 1 0 Acyltransferase family DUF2269 PF10027.4 EIW65451.1 - 0.013 15.2 11.2 0.024 14.3 5.1 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF4079 PF13301.1 EIW65451.1 - 0.039 13.9 4.9 0.47 10.4 2.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) COX15-CtaA PF02628.10 EIW65451.1 - 0.04 12.7 10.2 0.033 13.0 5.0 2.2 2 1 0 2 2 2 0 Cytochrome oxidase assembly protein DUF2254 PF10011.4 EIW65451.1 - 0.096 11.1 0.7 0.14 10.5 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF2231 PF09990.4 EIW65451.1 - 0.2 12.0 11.0 0.13 12.6 2.7 2.7 2 1 0 3 3 3 0 Predicted membrane protein (DUF2231) Ni_hydr_CYTB PF01292.15 EIW65451.1 - 0.42 9.9 15.0 2.9 7.2 0.1 2.8 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 DUF3488 PF11992.3 EIW65451.1 - 0.48 9.0 6.3 4.6 5.7 3.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3488) RDD PF06271.7 EIW65451.1 - 0.5 10.2 11.3 3.5 7.5 2.7 3.0 3 0 0 3 3 3 0 RDD family Cytochrom_B_N PF00033.14 EIW65451.1 - 2 7.7 14.3 0.18 11.1 2.7 2.7 1 1 2 3 3 3 0 Cytochrome b(N-terminal)/b6/petB FA_desaturase PF00487.19 EIW65451.1 - 3.4 7.0 13.1 19 4.5 6.8 2.2 1 1 1 2 2 2 0 Fatty acid desaturase MARVEL PF01284.18 EIW65451.1 - 3.7 7.3 9.5 5.3 6.8 5.1 2.2 2 1 0 2 2 2 0 Membrane-associating domain DUF872 PF05915.7 EIW65451.1 - 5.4 6.9 0.0 5.4 6.9 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF4233 PF14017.1 EIW65451.1 - 5.5 6.9 20.6 0.77 9.7 9.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4233) TUDOR PF00567.19 EIW65452.1 - 0.00088 19.0 0.0 0.002 17.9 0.0 1.6 2 0 0 2 2 2 1 Tudor domain Relaxase PF03432.9 EIW65452.1 - 0.0016 17.8 1.3 0.0024 17.3 0.9 1.2 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain SseC PF04888.7 EIW65452.1 - 5.6 6.2 11.4 8.9 5.5 7.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Phytase-like PF13449.1 EIW65453.1 - 7.8e-24 84.5 0.0 1.4e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Esterase-like activity of phytase DUF221 PF02714.10 EIW65454.1 - 3.1e-86 289.1 16.6 3.1e-86 289.1 11.5 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIW65454.1 - 7e-34 116.6 0.8 7e-34 116.6 0.6 2.9 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIW65454.1 - 1.8e-10 41.2 0.0 4.4e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) PDR_assoc PF08370.6 EIW65454.1 - 0.12 11.8 0.2 0.12 11.8 0.1 3.8 5 0 0 5 5 5 0 Plant PDR ABC transporter associated Sugar_tr PF00083.19 EIW65455.1 - 1e-89 301.1 17.4 1.5e-89 300.6 12.1 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW65455.1 - 2.4e-23 82.4 35.2 1.1e-19 70.4 4.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIW65455.1 - 0.019 14.7 1.6 0.11 12.3 0.1 2.5 2 0 0 2 2 2 0 MFS_1 like family RNase_PH PF01138.16 EIW65456.1 - 2e-20 73.4 0.0 3.6e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EIW65456.1 - 1.6e-09 37.5 0.0 2.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Peptidase_C14 PF00656.17 EIW65457.1 - 1.1e-65 221.8 0.0 1.4e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain PEPCK_ATP PF01293.15 EIW65457.1 - 0.18 10.2 0.1 0.64 8.4 0.0 1.8 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase Peptidase_C13 PF01650.13 EIW65457.1 - 0.51 9.5 1.8 6.7 5.9 0.1 2.3 1 1 1 2 2 2 0 Peptidase C13 family zf-HC5HC2H PF13771.1 EIW65458.1 - 0.087 12.9 1.2 0.13 12.4 0.8 1.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EIW65458.1 - 0.13 12.2 1.2 0.18 11.8 0.8 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain EDR1 PF14381.1 EIW65459.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 ELFV_dehydrog PF00208.16 EIW65460.1 - 2.9e-49 167.8 0.0 7.7e-49 166.4 0.0 1.7 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EIW65460.1 - 4.9e-21 74.0 0.6 2.1e-14 51.9 0.0 2.8 2 1 1 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EIW65460.1 - 0.0093 15.5 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pyridoxal_deC PF00282.14 EIW65462.1 - 1.8e-101 339.2 0.0 9e-70 234.9 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 EIW65462.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Transketolase_N PF00456.16 EIW65463.1 - 7e-148 491.8 0.1 9.1e-148 491.4 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EIW65463.1 - 1.8e-44 151.3 0.0 3.2e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIW65463.1 - 1.4e-11 44.4 0.0 3.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EIW65463.1 - 7.1e-06 25.1 0.1 1.2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EIW65463.1 - 0.00012 20.9 0.1 0.0002 20.2 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Phosphonate-bd PF12974.2 EIW65463.1 - 0.07 12.5 0.1 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Terpene_synth PF01397.16 EIW65463.1 - 0.12 11.6 0.4 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain Complex1_LYR_1 PF13232.1 EIW65464.1 - 7.5e-06 26.0 0.1 1.3e-05 25.3 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like UvsW PF11637.3 EIW65464.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW EI24 PF07264.6 EIW65465.1 - 1.9e-05 24.1 10.8 0.00016 21.1 7.2 2.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Fungal_trans PF04082.13 EIW65466.1 - 3.7e-11 42.3 0.0 1.1e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW65466.1 - 0.46 10.4 4.1 0.13 12.2 0.3 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.15 EIW65467.1 - 5e-25 88.8 0.0 1.3e-24 87.4 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIW65467.1 - 1.1e-23 84.7 0.1 1.5e-23 84.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EIW65467.1 - 4.8e-12 45.5 0.3 1.3e-11 44.1 0.1 1.8 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EIW65467.1 - 2.7e-06 26.8 0.0 0.0025 17.0 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.9 EIW65467.1 - 3.8e-05 23.3 0.0 0.00012 21.8 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase rve PF00665.21 EIW65468.1 - 0.0015 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_4 PF13359.1 EIW65470.1 - 3.6e-13 49.4 0.0 5.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2054 PF10218.4 EIW65470.1 - 0.05 13.4 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) BRCA-2_helical PF09169.5 EIW65470.1 - 0.058 12.9 0.0 0.98 8.9 0.0 2.1 2 0 0 2 2 2 0 BRCA2, helical 2OG-FeII_Oxy_2 PF13532.1 EIW65472.1 - 9.3e-10 38.6 0.0 1.7e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW65472.1 - 1.9e-05 24.8 0.0 0.00017 21.8 0.0 2.6 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CTP_transf_1 PF01148.15 EIW65473.1 - 1.1e-77 261.1 16.8 1.4e-77 260.8 11.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Hexapep PF00132.19 EIW65474.1 - 4.5e-07 29.0 0.6 9.6e-05 21.7 0.3 3.4 1 1 3 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EIW65474.1 - 1.2e-05 24.8 0.0 9.5e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EIW65474.1 - 0.072 12.6 0.3 0.91 9.1 0.3 2.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Mon1 PF03164.9 EIW65475.1 - 3.6e-113 378.2 0.0 4.2e-113 378.0 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 MG1 PF11974.3 EIW65475.1 - 0.02 15.4 0.0 0.051 14.1 0.0 1.7 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain zf-C2H2 PF00096.21 EIW65476.1 - 1.8 9.0 3.9 12 6.4 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type PP28 PF10252.4 EIW65478.1 - 5.1e-21 74.4 21.3 5.1e-21 74.4 14.7 2.6 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 CAF-1_p150 PF11600.3 EIW65478.1 - 0.27 10.5 26.8 0.39 10.0 18.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nop53 PF07767.6 EIW65478.1 - 3.2 6.6 28.4 1 8.2 17.3 1.7 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) XAP5 PF04921.9 EIW65478.1 - 9.7 5.6 17.1 27 4.2 11.9 1.8 1 1 0 1 1 1 0 XAP5, circadian clock regulator Acetyltransf_7 PF13508.1 EIW65479.1 - 4.9e-07 29.8 0.2 1.5e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW65479.1 - 1.4e-06 28.2 0.8 1.1e-05 25.3 0.6 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EIW65479.1 - 0.0045 17.5 0.1 0.047 14.2 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW65479.1 - 0.0046 17.0 0.1 0.26 11.4 0.0 2.5 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIW65479.1 - 0.0082 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EIW65479.1 - 0.025 14.3 0.2 0.06 13.1 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein VHS PF00790.14 EIW65480.1 - 3.7e-37 127.1 0.0 7.7e-37 126.0 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EIW65480.1 - 7.1e-19 67.6 0.0 1.8e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 GAT domain NAD_binding_10 PF13460.1 EIW65481.1 - 5.1e-16 59.1 0.0 6.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIW65481.1 - 1.3e-11 43.9 0.0 9.5e-10 37.8 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EIW65481.1 - 3e-11 43.2 0.1 5.7e-10 39.0 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW65481.1 - 5e-09 35.7 0.0 6.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EIW65481.1 - 3.6e-08 32.6 0.4 0.00027 19.9 0.1 3.1 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EIW65481.1 - 3e-06 26.1 0.0 7.1e-06 24.9 0.0 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EIW65481.1 - 0.0046 15.9 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Peptidase_S6 PF02395.11 EIW65481.1 - 0.072 11.2 0.0 0.094 10.8 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin A1 protease adh_short PF00106.20 EIW65481.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIW65481.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pro_CA PF00484.14 EIW65482.1 - 1.4e-39 135.4 0.0 1.7e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Methyltransf_24 PF13578.1 EIW65483.1 - 5.9e-14 52.7 0.0 1.4e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EIW65483.1 - 0.0069 15.4 0.0 0.015 14.3 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase MFS_1 PF07690.11 EIW65484.1 - 6.2e-12 44.9 53.5 1.3e-10 40.5 36.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EIW65485.1 - 1e-35 123.0 56.0 5.4e-35 120.7 38.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW65485.1 - 2.1e-10 39.7 14.2 2.1e-10 39.7 9.8 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter Tmemb_18A PF09771.4 EIW65485.1 - 8.3 6.4 9.3 1.9 8.4 1.2 2.5 2 0 0 2 2 2 0 Transmembrane protein 188 Sec10 PF07393.6 EIW65486.1 - 9.9e-234 777.6 0.0 1.2e-233 777.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 COG5 PF10392.4 EIW65486.1 - 0.2 11.5 3.3 0.33 10.9 0.0 2.8 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF3934 PF13070.1 EIW65487.1 - 0.025 14.7 0.1 0.037 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) FOLN PF09289.5 EIW65487.1 - 0.065 13.0 0.5 0.065 13.0 0.4 1.9 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain ThiF PF00899.16 EIW65488.1 - 4e-37 127.0 0.0 6.6e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EIW65488.1 - 1.2e-21 76.0 0.1 2.1e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EIW65488.1 - 2.4e-07 31.0 0.0 5.1e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain UDPG_MGDP_dh_N PF03721.9 EIW65488.1 - 0.075 12.4 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 EIW65488.1 - 0.13 12.4 0.0 1.4 9.0 0.0 2.3 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2587 PF10759.4 EIW65490.1 - 0.022 14.1 0.1 0.055 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) vMSA PF00695.14 EIW65491.1 - 0.15 11.2 0.2 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus CDC45 PF02724.9 EIW65492.1 - 0.24 9.4 13.3 0.34 8.8 9.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1509 PF07420.6 EIW65492.1 - 0.69 9.1 9.6 0.91 8.7 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF2079 PF09852.4 EIW65493.1 - 0.025 13.3 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Casein_kappa PF00997.13 EIW65493.1 - 3.1 7.4 4.9 6.1 6.5 3.4 1.4 1 0 0 1 1 1 0 Kappa casein zf-CCHC PF00098.18 EIW65496.1 - 0.016 15.0 4.8 0.029 14.2 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle PT PF04886.7 EIW65497.1 - 2.3 7.6 12.8 3.1 7.1 2.1 2.6 2 0 0 2 2 2 0 PT repeat Matrilin_ccoil PF10393.4 EIW65500.1 - 0.051 12.9 0.2 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Phage_GP20 PF06810.6 EIW65501.1 - 0.11 11.8 1.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 Trypan_PARP PF05887.6 EIW65502.1 - 0.0082 15.9 12.7 0.0082 15.9 8.8 3.5 2 1 1 3 3 3 1 Procyclic acidic repetitive protein (PARP) STAT2_C PF12188.3 EIW65504.1 - 0.0028 17.3 0.2 0.0069 16.1 0.2 1.6 1 0 0 1 1 1 1 Signal transducer and activator of transcription 2 C terminal Pkinase PF00069.20 EIW65504.1 - 0.055 12.6 0.1 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.18 EIW65508.1 - 0.058 13.1 1.3 0.31 10.7 0.9 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family DMAP_binding PF06464.6 EIW65509.1 - 0.047 14.2 1.0 0.14 12.7 0.7 1.8 1 0 0 1 1 1 0 DMAP1-binding Domain DDE_1 PF03184.14 EIW65510.1 - 2.8e-11 42.9 0.1 1.3e-10 40.8 0.0 1.9 1 1 1 2 2 2 1 DDE superfamily endonuclease CBM_5_12_2 PF14600.1 EIW65510.1 - 0.038 13.6 0.1 0.087 12.4 0.1 1.5 1 0 0 1 1 1 0 Cellulose-binding domain DDE_1 PF03184.14 EIW65511.1 - 1.6e-32 112.4 0.0 2.6e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_2 PF07727.9 EIW65512.1 - 3e-10 39.4 0.0 3.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helitron_like_N PF14214.1 EIW65515.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Peptidase_C48 PF02902.14 EIW65519.1 - 1.5e-15 57.4 0.1 1.9e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RskA PF10099.4 EIW65520.1 - 0.0023 17.6 0.5 0.63 9.7 0.1 2.5 2 0 0 2 2 2 2 Anti-sigma-K factor rskA Tetraspannin PF00335.15 EIW65520.1 - 0.047 12.9 4.1 0.091 12.0 2.8 1.4 1 0 0 1 1 1 0 Tetraspanin family EphA2_TM PF14575.1 EIW65520.1 - 0.54 10.6 0.0 0.54 10.6 0.0 2.7 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Myosin_head PF00063.16 EIW65521.1 - 7.3e-47 159.8 0.1 3.1e-44 151.1 0.1 3.0 1 1 0 1 1 1 1 Myosin head (motor domain) Atg14 PF10186.4 EIW65521.1 - 0.00086 18.3 1.4 0.00086 18.3 1.0 1.6 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Laminin_I PF06008.9 EIW65521.1 - 0.0097 15.2 6.4 0.031 13.5 4.4 1.8 1 1 0 1 1 1 1 Laminin Domain I DBI_PRT PF02277.12 EIW65521.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase IstB_IS21 PF01695.12 EIW65521.1 - 0.015 14.7 0.1 0.097 12.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Phage_GP20 PF06810.6 EIW65521.1 - 0.029 13.7 3.9 0.077 12.4 2.7 1.7 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF869 PF05911.6 EIW65521.1 - 0.038 12.2 10.6 0.06 11.5 7.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) NPV_P10 PF05531.7 EIW65521.1 - 0.041 14.1 1.6 0.26 11.5 0.3 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Mg_chelatase PF01078.16 EIW65521.1 - 0.075 12.1 0.0 0.19 10.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Tropomyosin_1 PF12718.2 EIW65521.1 - 0.39 10.5 12.2 0.16 11.8 6.4 2.0 2 0 0 2 2 2 0 Tropomyosin like RasGAP_C PF03836.10 EIW65521.1 - 0.81 9.3 8.7 15 5.2 5.4 3.3 2 1 0 2 2 2 0 RasGAP C-terminus DUF1664 PF07889.7 EIW65521.1 - 2.2 8.0 6.6 1 9.1 1.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3321 PF11968.3 EIW65524.1 - 3.3e-16 59.5 0.0 6.6e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Periviscerokin PF08259.6 EIW65525.1 - 0.00016 21.2 2.2 1.6e+02 2.9 0.0 8.0 10 0 0 10 10 10 0 Periviscerokinin family RRM_1 PF00076.17 EIW65525.1 - 0.15 11.7 0.0 10 5.8 0.0 3.0 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Periviscerokin PF08259.6 EIW65526.1 - 2.3e-06 26.9 1.5 75 3.9 0.0 7.2 8 0 0 8 8 8 0 Periviscerokinin family NADH_dh_m_C1 PF15088.1 EIW65526.1 - 0.00063 19.1 2.7 11 5.5 0.1 4.9 4 1 2 6 6 6 3 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DUF1349 PF07081.6 EIW65526.1 - 0.0014 18.0 2.8 0.32 10.3 0.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1349) CfAFP PF05264.6 EIW65527.1 - 0.01 15.6 1.9 0.059 13.1 0.5 2.4 2 1 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF1317 PF07026.6 EIW65527.1 - 0.019 14.8 0.8 3.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1317) Tom22 PF04281.8 EIW65529.1 - 0.1 12.0 1.1 2.4 7.6 0.1 2.2 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 DDE_1 PF03184.14 EIW65530.1 - 1.7e-37 128.6 0.0 2.1e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HELP PF03451.9 EIW65530.1 - 0.026 14.0 0.1 0.062 12.8 0.0 1.6 2 0 0 2 2 2 0 HELP motif DAP PF15228.1 EIW65535.1 - 0.043 14.5 3.2 0.043 14.5 2.2 1.7 2 0 0 2 2 2 0 Death-associated protein SR-25 PF10500.4 EIW65540.1 - 0.77 9.1 3.9 1 8.7 2.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Asp_protease_2 PF13650.1 EIW65541.1 - 0.00012 22.5 0.0 0.0002 21.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EIW65541.1 - 0.00022 20.9 2.2 0.00035 20.3 1.5 1.3 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.1 EIW65541.1 - 0.0023 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.1 EIW65541.1 - 0.007 15.8 0.1 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 EIW65541.1 - 0.12 12.2 1.1 0.26 11.1 0.1 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.1 EIW65541.1 - 0.16 11.7 0.9 0.24 11.1 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIW65541.1 - 0.44 10.0 3.2 0.71 9.4 2.2 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DDE_1 PF03184.14 EIW65542.1 - 3.2e-25 88.5 0.6 6.6e-25 87.5 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW65542.1 - 0.0013 18.4 0.0 0.0035 17.1 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CAF-1_p150 PF11600.3 EIW65542.1 - 0.42 9.9 28.3 0.67 9.3 19.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Draxin PF15550.1 EIW65542.1 - 1.5 8.4 12.4 2.2 7.8 8.6 1.2 1 0 0 1 1 1 0 Draxin Ycf1 PF05758.7 EIW65542.1 - 2.4 5.7 7.1 3.1 5.3 4.9 1.1 1 0 0 1 1 1 0 Ycf1 ALMT PF11744.3 EIW65543.1 - 0.017 13.8 0.2 0.018 13.7 0.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter HSBP1 PF06825.7 EIW65543.1 - 0.18 11.3 3.8 11 5.6 0.0 3.2 3 1 0 3 3 3 0 Heat shock factor binding protein 1 CENP-H PF05837.7 EIW65543.1 - 0.2 11.8 12.9 0.068 13.3 5.9 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PKK PF12474.3 EIW65543.1 - 0.32 10.7 17.5 0.58 9.8 11.6 2.0 1 1 0 1 1 1 0 Polo kinase kinase OmpH PF03938.9 EIW65543.1 - 3 7.7 14.1 5.7 6.8 9.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.8 EIW65543.1 - 3.1 6.7 10.3 4.7 6.1 7.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein TACC PF05010.9 EIW65549.1 - 0.014 15.1 3.4 0.018 14.8 2.3 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Peptidase_C14 PF00656.17 EIW65549.1 - 0.023 14.3 1.0 0.037 13.7 0.7 1.4 1 1 0 1 1 1 0 Caspase domain Sigma_1_2 PF03084.9 EIW65549.1 - 0.072 11.7 1.3 1 7.9 0.1 2.0 1 1 1 2 2 2 0 Reoviral Sigma1/Sigma2 family CALCOCO1 PF07888.6 EIW65549.1 - 0.11 10.7 9.1 0.14 10.3 6.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cortex-I_coil PF09304.5 EIW65549.1 - 0.74 9.8 9.7 30 4.6 0.5 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil Tropomyosin_1 PF12718.2 EIW65549.1 - 1.1 9.1 9.1 4.6 7.0 3.8 2.2 1 1 1 2 2 2 0 Tropomyosin like Med4 PF10018.4 EIW65549.1 - 1.1 8.5 7.0 0.37 10.1 2.7 1.8 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Nsp1_C PF05064.8 EIW65549.1 - 8.8 6.0 9.6 3.5 7.3 2.1 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region HALZ PF02183.13 EIW65550.1 - 0.0026 17.4 0.8 0.0067 16.1 0.5 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper NPV_P10 PF05531.7 EIW65552.1 - 0.014 15.6 0.4 0.091 13.0 0.1 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.13 EIW65552.1 - 0.02 14.4 1.0 0.02 14.4 0.7 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EIW65552.1 - 0.052 13.3 0.5 0.15 11.9 0.2 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EIW65552.1 - 0.19 11.5 0.4 0.35 10.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LPP PF04728.8 EIW65552.1 - 0.27 11.0 3.9 0.11 12.3 0.4 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper SH2 PF00017.19 EIW65554.1 - 0.058 13.1 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 SH2 domain gag-asp_proteas PF13975.1 EIW65555.1 - 2.6e-05 23.9 0.0 4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIW65555.1 - 2.8e-05 24.5 0.0 3.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIW65555.1 - 0.0032 17.4 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EIW65555.1 - 0.016 15.0 0.0 0.027 14.4 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.5 EIW65555.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease zf-C2H2 PF00096.21 EIW65556.1 - 0.69 10.3 3.5 1.1 9.6 0.7 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Daxx PF03344.10 EIW65557.1 - 0.006 15.1 13.6 0.0089 14.5 9.4 1.4 1 0 0 1 1 1 1 Daxx Family BSP_II PF05432.6 EIW65557.1 - 0.013 14.8 19.5 0.026 13.8 13.5 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 EIW65557.1 - 0.013 15.8 3.5 0.013 15.8 2.4 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Hid1 PF12722.2 EIW65557.1 - 0.057 11.1 3.6 0.078 10.6 2.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF605 PF04652.11 EIW65557.1 - 3.2 7.0 15.0 6 6.1 10.4 1.4 1 0 0 1 1 1 0 Vta1 like TFIIF_alpha PF05793.7 EIW65557.1 - 5 5.3 26.8 0.33 9.2 14.6 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GRP PF07172.6 EIW65558.1 - 6.2e-05 23.3 8.1 9.4e-05 22.8 5.6 1.3 1 0 0 1 1 1 1 Glycine rich protein family Mac PF12464.3 EIW65561.1 - 0.076 13.0 0.2 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Maltose acetyltransferase SR-25 PF10500.4 EIW65561.1 - 0.49 9.8 8.6 0.63 9.4 5.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cep57_CLD_2 PF14197.1 EIW65561.1 - 4 7.4 7.3 0.92 9.4 2.9 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Pkinase PF00069.20 EIW65562.1 - 0.0023 17.1 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW65562.1 - 0.025 13.6 0.1 0.041 12.9 0.1 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase UBA_e1_thiolCys PF10585.4 EIW65564.1 - 0.47 9.8 1.6 0.9 8.9 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Cytochrom_B558a PF05038.8 EIW65566.1 - 1.2 8.7 3.0 2.6 7.6 2.1 1.6 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit zf-CCHC PF00098.18 EIW65567.1 - 0.00064 19.5 1.5 0.0012 18.6 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW65567.1 - 0.35 11.1 8.0 0.092 12.9 3.4 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW65567.1 - 0.63 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Periviscerokin PF08259.6 EIW65569.1 - 2.2e-05 23.9 1.0 94 3.6 0.0 6.0 6 0 0 6 6 6 0 Periviscerokinin family SH3_2 PF07653.12 EIW65569.1 - 0.00058 19.3 2.2 35 3.9 0.0 5.4 5 1 1 6 6 6 1 Variant SH3 domain NADH_dh_m_C1 PF15088.1 EIW65569.1 - 0.0016 17.8 2.7 15 5.1 0.0 4.6 2 1 3 5 5 5 2 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Periviscerokin PF08259.6 EIW65570.1 - 0.00032 20.3 4.5 95 3.6 0.0 6.5 7 0 0 7 7 7 0 Periviscerokinin family SH2 PF00017.19 EIW65570.1 - 0.0047 16.6 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 2 SH2 domain SH3_2 PF07653.12 EIW65570.1 - 0.012 15.1 1.1 1.1e+02 2.3 0.0 4.8 5 0 0 5 5 5 0 Variant SH3 domain NADH_dh_m_C1 PF15088.1 EIW65570.1 - 0.06 12.8 5.1 33 4.0 0.0 4.5 2 2 2 4 4 4 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Kdo PF06293.9 EIW65571.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW65571.1 - 0.025 14.3 0.4 0.033 13.9 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EIW65571.1 - 0.12 11.3 0.1 0.33 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 EIW65571.1 - 0.17 11.0 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Chromo PF00385.19 EIW65574.1 - 3.9e-10 39.2 0.2 4.8e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DZR PF12773.2 EIW65575.1 - 0.014 15.1 0.9 0.014 15.1 0.6 2.0 1 1 1 2 2 2 0 Double zinc ribbon DUF164 PF02591.10 EIW65575.1 - 0.079 12.8 0.5 0.079 12.8 0.3 1.8 2 0 0 2 2 2 0 Putative zinc ribbon domain DUF1289 PF06945.8 EIW65575.1 - 2.1 7.8 6.9 1.3 8.5 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Myosin_head PF00063.16 EIW65577.1 - 3.2e-05 22.1 0.0 5.4e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DUF4457 PF14652.1 EIW65577.1 - 0.063 12.2 0.8 0.11 11.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) Zip PF02535.17 EIW65578.1 - 0.0072 15.3 15.3 0.0098 14.9 10.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Macoilin PF09726.4 EIW65578.1 - 0.09 11.0 5.1 0.095 10.9 3.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2946 PF11162.3 EIW65578.1 - 7 6.8 11.6 12 6.1 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Tom7 PF08038.7 EIW65584.1 - 0.00056 19.2 2.8 30 4.1 0.0 4.9 2 2 3 5 5 5 0 TOM7 family Senescence PF06911.7 EIW65584.1 - 0.045 13.4 0.7 3.4 7.3 0.1 2.0 1 1 1 2 2 2 0 Senescence-associated protein Stirrup PF09061.1 EIW65584.1 - 0.17 11.8 0.4 28 4.7 0.0 2.7 1 1 2 3 3 3 0 Stirrup Oxygenase-NA PF09859.4 EIW65584.1 - 0.68 9.2 5.9 2.3 7.5 0.6 2.5 1 1 1 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA Filaggrin PF03516.8 EIW65584.1 - 1.2 9.6 7.2 92 3.6 3.0 3.4 1 1 1 2 2 2 0 Filaggrin DUF4611 PF15387.1 EIW65585.1 - 0.014 15.5 0.1 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DDE_1 PF03184.14 EIW65589.1 - 1e-30 106.5 0.0 2.5e-29 101.9 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW65589.1 - 0.023 14.4 0.1 0.023 14.4 0.1 2.1 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EIW65589.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Histone PF00125.19 EIW65595.1 - 0.019 15.0 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DEADboxA PF12343.3 EIW65595.1 - 0.18 12.1 1.5 3.1 8.1 1.4 2.1 1 1 1 2 2 2 0 Cold shock protein DEAD box A Integrase_AP2 PF14657.1 EIW65600.1 - 0.5 10.1 3.9 0.85 9.4 2.7 1.3 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain SlyX PF04102.7 EIW65601.1 - 0.013 15.8 5.3 0.015 15.6 2.6 1.9 2 1 0 2 2 2 0 SlyX DUF536 PF04394.9 EIW65601.1 - 0.014 15.1 3.8 0.014 15.1 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF536 GAGA_bind PF06217.7 EIW65601.1 - 0.023 14.6 0.2 0.027 14.4 0.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3552 PF12072.3 EIW65601.1 - 0.025 13.8 6.1 0.044 12.9 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Myc_N PF01056.13 EIW65602.1 - 0.045 12.9 0.1 0.086 11.9 0.1 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Periviscerokin PF08259.6 EIW65604.1 - 6.8e-07 28.5 1.9 1.3e+02 3.2 0.0 7.3 7 0 0 7 7 7 0 Periviscerokinin family NADH_dh_m_C1 PF15088.1 EIW65604.1 - 0.0084 15.5 5.6 25 4.4 0.1 4.9 2 2 2 4 4 4 3 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial SLS PF14611.1 EIW65605.1 - 0.083 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator 14-3-3 PF00244.15 EIW65610.1 - 9.2e-05 21.6 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 14-3-3 protein EnY2 PF10163.4 EIW65612.1 - 0.025 14.5 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 SGS PF05002.10 EIW65616.1 - 3.4 7.4 10.3 11 5.8 6.8 2.2 1 1 0 1 1 1 0 SGS domain DUF3022 PF11226.3 EIW65617.1 - 0.12 12.2 0.1 22 4.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3022) Tn7_TnsC_Int PF11426.3 EIW65618.1 - 0.0011 18.6 0.9 0.0036 16.9 0.6 1.9 1 0 0 1 1 1 1 Tn7 transposition regulator TnsC Fer2 PF00111.22 EIW65619.1 - 7.2e-11 41.6 0.2 9.9e-11 41.2 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CK_II_beta PF01214.13 EIW65620.1 - 3.5e-75 251.5 0.0 4.4e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit zf-ribbon_3 PF13248.1 EIW65620.1 - 0.22 10.7 1.9 0.26 10.5 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Nucleoplasmin PF03066.10 EIW65620.1 - 1.5 8.3 4.5 2.4 7.6 3.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin GDI PF00996.13 EIW65621.1 - 3.8e-199 661.5 0.0 4.3e-199 661.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor His_Phos_2 PF00328.17 EIW65622.1 - 1.9e-35 122.8 0.0 3e-35 122.1 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PT PF04886.7 EIW65623.1 - 0.037 13.3 13.2 0.095 12.0 9.2 1.7 1 0 0 1 1 1 0 PT repeat WD40 PF00400.27 EIW65625.1 - 1e-44 148.8 6.8 6.6e-08 32.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW65625.1 - 0.0022 17.4 0.1 0.2 11.0 0.0 2.9 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.16 EIW65625.1 - 0.1 12.1 3.6 5.4 6.7 0.0 4.3 5 0 0 5 5 5 0 PQQ enzyme repeat Nup160 PF11715.3 EIW65625.1 - 0.13 10.3 0.0 0.48 8.4 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 UCH PF00443.24 EIW65626.1 - 8.5e-12 44.7 0.0 1.8e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MULE PF10551.4 EIW65626.1 - 1.9e-06 27.9 0.1 0.00026 21.1 0.1 3.0 1 1 0 1 1 1 1 MULE transposase domain MutS_III PF05192.13 EIW65627.1 - 0.00098 18.9 2.0 0.0025 17.6 1.5 1.5 1 1 0 1 1 1 1 MutS domain III TPR_MLP1_2 PF07926.7 EIW65627.1 - 0.0036 17.0 13.4 0.036 13.7 1.5 2.9 2 1 0 2 2 2 2 TPR/MLP1/MLP2-like protein TMCO5 PF14992.1 EIW65627.1 - 1.7 7.6 15.9 4.6 6.2 2.8 2.0 1 1 1 2 2 2 0 TMCO5 family Seryl_tRNA_N PF02403.17 EIW65627.1 - 2.5 8.1 13.3 0.53 10.3 5.5 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MOZ_SAS PF01853.13 EIW65628.1 - 2.3e-73 245.4 0.1 4e-73 244.6 0.1 1.4 1 0 0 1 1 1 1 MOZ/SAS family ACOX PF01756.14 EIW65629.1 - 4.9e-50 169.5 0.0 8e-50 168.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EIW65629.1 - 2.2e-14 52.6 1.7 2.3e-13 49.4 1.1 2.6 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EIW65629.1 - 1.6e-11 44.5 0.1 1e-10 41.9 0.0 2.4 3 0 0 3 3 3 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 EIW65629.1 - 1.7e-06 28.2 0.1 6.3e-06 26.3 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PT PF04886.7 EIW65632.1 - 0.019 14.2 13.8 0.082 12.2 2.0 2.2 1 1 1 2 2 2 0 PT repeat TAF8_C PF10406.4 EIW65632.1 - 0.041 13.9 35.8 0.5 10.4 2.2 4.5 1 1 4 5 5 5 0 Transcription factor TFIID complex subunit 8 C-term DDE_3 PF13358.1 EIW65633.1 - 3.9e-10 39.6 0.0 5.3e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIW65633.1 - 7.2e-10 38.7 0.9 1.7e-09 37.6 0.6 1.6 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.1 EIW65633.1 - 1.4e-07 30.9 0.7 0.00013 21.4 0.0 2.8 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 EIW65633.1 - 2.3e-07 30.9 0.9 3e-06 27.3 0.1 2.3 1 1 1 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 EIW65633.1 - 8.4e-07 28.8 1.5 0.0011 18.8 0.1 3.1 2 1 1 3 3 3 2 Helix-turn-helix domain MarR_2 PF12802.2 EIW65633.1 - 7e-06 25.6 0.0 0.0053 16.3 0.0 2.6 2 0 0 2 2 2 2 MarR family HTH_IclR PF09339.5 EIW65633.1 - 8.2e-05 22.1 0.0 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_38 PF13936.1 EIW65633.1 - 0.00019 20.8 0.2 0.0034 16.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.1 EIW65633.1 - 0.00044 19.5 0.0 0.12 11.8 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.11 EIW65633.1 - 0.00045 19.4 0.0 0.41 10.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EIW65633.1 - 0.0011 18.4 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_20 PF12840.2 EIW65633.1 - 0.0016 18.2 0.0 0.036 13.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIW65633.1 - 0.0038 18.0 5.5 0.0091 16.7 2.7 2.4 2 1 1 3 3 2 1 Homeodomain-like domain Terminase_5 PF06056.7 EIW65633.1 - 0.0096 15.4 0.1 0.064 12.8 0.0 2.3 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) DUF3489 PF11994.3 EIW65633.1 - 0.029 14.3 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Sigma70_r4_2 PF08281.7 EIW65633.1 - 0.032 13.6 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_30 PF13556.1 EIW65633.1 - 0.1 12.1 0.2 6.8 6.3 0.0 3.2 4 0 0 4 4 4 0 PucR C-terminal helix-turn-helix domain HTH_3 PF01381.17 EIW65633.1 - 0.15 11.9 0.1 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix UBN2_3 PF14244.1 EIW65635.1 - 0.0051 16.3 0.1 0.025 14.1 0.0 2.0 2 1 1 3 3 3 1 gag-polypeptide of LTR copia-type SUR7 PF06687.7 EIW65637.1 - 1.2e-08 34.8 14.6 2e-06 27.5 10.1 2.0 1 1 0 1 1 1 1 SUR7/PalI family NrfD PF03916.9 EIW65637.1 - 0.00041 19.8 1.9 0.00061 19.3 1.3 1.3 1 0 0 1 1 1 1 Polysulphide reductase, NrfD DUF1622 PF07784.6 EIW65637.1 - 0.002 17.7 0.4 0.78 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1622) PMP22_Claudin PF00822.15 EIW65637.1 - 0.025 14.2 9.3 0.017 14.7 2.6 2.1 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family ABC2_membrane_5 PF13346.1 EIW65637.1 - 0.042 13.1 6.8 0.079 12.2 1.9 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Claudin_2 PF13903.1 EIW65637.1 - 0.14 11.8 13.9 0.57 9.8 8.2 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction H_PPase PF03030.11 EIW65637.1 - 0.15 10.3 1.2 0.23 9.6 0.8 1.2 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase YlaC PF10777.4 EIW65637.1 - 0.21 11.1 1.5 0.41 10.1 1.0 1.4 1 0 0 1 1 1 0 Inner membrane protein YlaC PGG PF13962.1 EIW65637.1 - 0.32 10.6 9.7 0.059 12.9 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function MARVEL PF01284.18 EIW65637.1 - 0.46 10.2 9.2 1.9 8.3 6.4 2.0 1 1 0 1 1 1 0 Membrane-associating domain PalH PF08733.5 EIW65637.1 - 0.55 9.0 3.7 1.8 7.3 2.6 1.7 1 1 0 1 1 1 0 PalH/RIM21 DUF2975 PF11188.3 EIW65637.1 - 3.3 7.4 12.6 2.5 7.8 7.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) Ribosomal_60s PF00428.14 EIW65638.1 - 8e-23 80.6 12.8 3.4e-22 78.6 7.9 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.15 EIW65638.1 - 9.6e-23 80.0 0.1 1.5e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 DegV PF02645.11 EIW65638.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 BDV_P40 PF06407.6 EIW65638.1 - 0.02 13.7 0.1 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Borna disease virus P40 protein CytochromB561_N PF09786.4 EIW65643.1 - 0.021 13.3 0.0 0.028 12.8 0.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal zf-CCHC PF00098.18 EIW65647.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW65647.1 - 0.33 11.1 8.4 0.087 13.0 3.7 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW65647.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW65648.1 - 0.048 13.0 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Methyltransf_18 PF12847.2 EIW65650.1 - 6.3e-07 29.9 0.0 2e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW65650.1 - 7.7e-05 23.1 0.0 0.00033 21.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW65650.1 - 0.00013 21.6 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW65650.1 - 0.016 15.7 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EIW65651.1 - 1e-19 71.0 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW65651.1 - 5.1e-11 42.5 0.0 8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW65651.1 - 0.00063 19.2 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EIW65651.1 - 0.0017 18.2 0.0 0.0024 17.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIW65651.1 - 0.0029 17.6 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EIW65651.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EIW65651.1 - 0.033 14.4 0.0 0.083 13.1 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding DFP PF04127.10 EIW65651.1 - 0.042 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.10 EIW65651.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-HIT PF04438.11 EIW65652.1 - 0.00079 19.0 7.8 0.0012 18.3 5.4 1.4 1 0 0 1 1 1 1 HIT zinc finger TMEM51 PF15345.1 EIW65652.1 - 0.018 14.7 5.3 0.021 14.4 3.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Glyco_hydro_71 PF03659.9 EIW65656.1 - 2e-109 365.6 5.1 3.5e-109 364.8 3.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.14 EIW65656.1 - 7.9e-34 115.4 21.9 4.1e-17 61.8 4.8 3.0 2 0 0 2 2 2 2 WSC domain UBN2_3 PF14244.1 EIW65658.1 - 0.0035 16.9 1.3 0.37 10.3 0.6 2.7 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIW65658.1 - 0.014 14.9 0.1 0.034 13.7 0.1 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type SBP_bac_1 PF01547.20 EIW65658.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein UBN2 PF14223.1 EIW65658.1 - 0.18 11.6 0.3 0.35 10.6 0.2 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Pyr_redox_2 PF07992.9 EIW65660.1 - 0.0062 16.4 0.0 0.031 14.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Kelch_1 PF01344.20 EIW65660.1 - 0.0062 16.0 0.1 4 7.0 0.1 2.4 2 0 0 2 2 2 2 Kelch motif NAD_binding_9 PF13454.1 EIW65660.1 - 0.066 12.9 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Resolvase PF00239.16 EIW65663.1 - 0.018 14.8 2.1 0.039 13.8 1.5 1.5 1 0 0 1 1 1 0 Resolvase, N terminal domain BRF1 PF07741.8 EIW65663.1 - 0.091 12.9 2.8 0.26 11.5 1.9 1.7 1 0 0 1 1 1 0 Brf1-like TBP-binding domain ROKNT PF08067.6 EIW65665.1 - 0.13 12.1 0.3 0.13 12.1 0.2 1.9 2 0 0 2 2 2 0 ROKNT (NUC014) domain DUF3505 PF12013.3 EIW65666.1 - 5.1e-10 39.5 2.8 5.1e-10 39.5 1.9 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 EIW65666.1 - 8.5 6.5 11.3 0.93 9.6 0.4 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.20 EIW65667.1 - 0.0001 21.5 0.0 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW65667.1 - 0.00023 20.3 0.0 0.0042 16.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EIW65667.1 - 0.0054 15.8 0.0 0.0087 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF346 PF03984.8 EIW65667.1 - 0.15 11.5 1.6 0.3 10.5 1.1 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) FAP PF07174.6 EIW65668.1 - 1.6 7.9 20.5 3 7.0 14.2 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) MULE PF10551.4 EIW65669.1 - 4.7e-13 49.1 0.0 5.5e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EIW65669.1 - 2.1e-05 23.2 0.1 2.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.12 EIW65669.1 - 0.017 14.6 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 Transposase NAGLU_N PF12971.2 EIW65669.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.4 1 1 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain FragX_IP PF05994.6 EIW65669.1 - 0.032 12.0 0.0 0.036 11.8 0.0 1.0 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family SR-25 PF10500.4 EIW65674.1 - 0.059 12.8 27.7 0.019 14.4 8.0 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.18 EIW65675.1 - 0.0009 19.0 1.9 0.0015 18.3 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW65675.1 - 0.025 14.3 0.2 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle HSBP1 PF06825.7 EIW65681.1 - 0.00095 18.6 2.1 0.00095 18.6 1.5 2.2 2 1 0 2 2 2 1 Heat shock factor binding protein 1 DUF1423 PF07227.6 EIW65681.1 - 0.0092 14.6 2.6 0.011 14.3 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1423) Vps5 PF09325.5 EIW65681.1 - 0.058 12.6 5.1 0.22 10.7 3.5 1.8 1 1 0 1 1 1 0 Vps5 C terminal like TMF_TATA_bd PF12325.3 EIW65681.1 - 0.17 11.6 12.5 0.052 13.2 6.1 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.6 EIW65681.1 - 0.23 10.1 6.6 0.35 9.4 4.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TBCA PF02970.11 EIW65681.1 - 0.25 11.4 9.5 0.19 11.8 2.2 2.2 1 1 0 2 2 2 0 Tubulin binding cofactor A APG6 PF04111.7 EIW65681.1 - 0.51 9.3 5.3 0.65 8.9 3.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EIW65681.1 - 0.61 9.9 12.8 1 9.2 8.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 EIW65681.1 - 1.4 8.4 7.4 4.1 6.9 0.3 2.8 1 1 2 3 3 3 0 Septum formation initiator IncA PF04156.9 EIW65681.1 - 1.7 8.2 8.3 3.1 7.3 5.7 1.4 1 0 0 1 1 1 0 IncA protein Kinesin PF00225.18 EIW65683.1 - 2e-23 82.6 1.1 4.3e-21 74.9 0.8 2.0 1 1 0 1 1 1 1 Kinesin motor domain Kinesin PF00225.18 EIW65684.1 - 2.5e-17 62.6 0.0 6e-17 61.3 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Tocopherol_cycl PF14249.1 EIW65684.1 - 0.11 11.1 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Tocopherol cyclase Myosin_head PF00063.16 EIW65685.1 - 6.1e-11 41.1 0.0 7.1e-11 40.8 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) NPV_P10 PF05531.7 EIW65688.1 - 0.0071 16.5 8.7 0.0084 16.3 4.7 2.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EIW65688.1 - 0.013 15.3 2.1 0.021 14.6 1.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Curto_V3 PF07436.6 EIW65688.1 - 0.043 13.9 0.3 0.12 12.5 0.2 1.7 1 0 0 1 1 1 0 Curtovirus V3 protein HSBP1 PF06825.7 EIW65688.1 - 0.058 12.9 3.8 0.12 11.9 2.6 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Prefoldin_3 PF13758.1 EIW65688.1 - 0.062 13.0 1.8 0.15 11.8 0.8 2.0 1 1 1 2 2 2 0 Prefoldin subunit EMP24_GP25L PF01105.19 EIW65688.1 - 0.62 9.7 3.6 1.2 8.8 2.5 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD LPP PF04728.8 EIW65688.1 - 2.7 7.8 9.7 5.7 6.8 5.8 2.1 1 1 0 1 1 1 0 Lipoprotein leucine-zipper gag-asp_proteas PF13975.1 EIW65689.1 - 7.5e-08 32.0 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIW65689.1 - 2.9e-05 24.4 0.0 4.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EIW65689.1 - 4.6e-05 23.1 0.8 8.6e-05 22.2 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Peptidase_A2B PF12384.3 EIW65689.1 - 0.0011 18.3 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase zf-CCHC_2 PF13696.1 EIW65689.1 - 0.0043 16.5 0.8 0.024 14.1 0.1 2.2 2 0 0 2 2 2 1 Zinc knuckle RVP PF00077.15 EIW65689.1 - 0.0088 15.9 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease DUF2587 PF10759.4 EIW65690.1 - 0.06 12.7 0.1 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF2587 PF10759.4 EIW65691.1 - 0.067 12.5 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Myosin_tail_1 PF01576.14 EIW65692.1 - 0.0032 15.2 5.5 0.0039 15.0 3.8 1.1 1 0 0 1 1 1 1 Myosin tail DUF869 PF05911.6 EIW65692.1 - 0.0087 14.3 2.0 0.011 14.0 1.4 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DivIC PF04977.10 EIW65692.1 - 0.009 15.4 2.7 0.009 15.4 1.9 2.6 1 1 1 3 3 3 1 Septum formation initiator GAS PF13851.1 EIW65692.1 - 0.013 14.6 7.4 0.02 14.1 5.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1202 PF06717.6 EIW65692.1 - 0.024 13.9 0.5 0.053 12.7 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1202) Herpes_U30 PF04523.8 EIW65692.1 - 0.027 11.9 0.1 0.034 11.6 0.1 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 TBPIP PF07106.8 EIW65692.1 - 0.04 13.4 4.4 0.061 12.8 3.0 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 EIW65692.1 - 0.049 12.8 0.1 0.071 12.2 0.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 EIW65692.1 - 0.073 12.1 3.6 0.098 11.6 2.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 EIW65692.1 - 0.074 11.5 2.3 0.09 11.2 1.6 1.1 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 EIW65692.1 - 0.077 12.8 8.8 0.18 11.6 6.1 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 EIW65692.1 - 0.083 12.8 0.8 0.49 10.3 0.1 2.4 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 EIW65692.1 - 0.099 13.0 2.6 0.31 11.4 0.2 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal PspA_IM30 PF04012.7 EIW65692.1 - 0.11 11.8 6.2 0.087 12.1 3.2 1.5 1 1 1 2 2 2 0 PspA/IM30 family Uds1 PF15456.1 EIW65692.1 - 0.13 12.2 8.3 0.19 11.7 5.0 1.9 2 1 0 2 2 1 0 Up-regulated During Septation DUF972 PF06156.8 EIW65692.1 - 0.19 12.0 5.3 0.47 10.8 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 EIW65692.1 - 0.22 11.2 6.8 0.49 10.1 4.6 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.3 EIW65692.1 - 0.29 10.4 2.9 0.42 9.9 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Prefoldin_2 PF01920.15 EIW65692.1 - 0.4 10.4 6.5 3.3 7.5 0.5 2.8 1 1 2 3 3 3 0 Prefoldin subunit COG2 PF06148.6 EIW65692.1 - 0.43 10.4 2.3 0.93 9.3 0.8 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.17 EIW65692.1 - 0.87 9.6 6.2 0.78 9.7 3.4 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 EIW65692.1 - 1.1 8.9 6.2 1.7 8.2 4.3 1.3 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 EIW65692.1 - 1.2 8.6 4.6 2.3 7.7 3.2 1.5 1 1 0 1 1 1 0 IncA protein TSC22 PF01166.13 EIW65692.1 - 3.3 7.7 4.9 9.5 6.2 0.7 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family Imm13 PF15564.1 EIW65693.1 - 0.088 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 13 Daxx PF03344.10 EIW65694.1 - 0.0085 14.6 11.2 0.01 14.4 7.8 1.0 1 0 0 1 1 1 1 Daxx Family BSP_II PF05432.6 EIW65694.1 - 0.01 15.1 15.6 0.015 14.6 10.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 EIW65694.1 - 0.034 12.0 10.1 0.038 11.9 7.0 1.0 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EIW65694.1 - 0.14 11.7 15.0 0.19 11.2 10.4 1.1 1 0 0 1 1 1 0 Nucleoplasmin BUD22 PF09073.5 EIW65694.1 - 0.33 9.9 7.3 0.41 9.6 5.0 1.0 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.8 EIW65694.1 - 0.59 9.7 9.3 0.71 9.4 6.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 EIW65694.1 - 0.71 9.0 10.3 0.88 8.7 7.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF1510 PF07423.6 EIW65694.1 - 1.2 8.4 8.0 1.6 8.0 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 EIW65694.1 - 1.2 8.8 13.6 1.8 8.3 9.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Prothymosin PF03247.9 EIW65694.1 - 1.3 9.1 27.7 1.8 8.7 19.2 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family SDA1 PF05285.7 EIW65694.1 - 1.3 8.2 10.6 1.6 7.9 7.3 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.6 EIW65694.1 - 2.3 7.6 15.0 3.1 7.2 10.4 1.1 1 0 0 1 1 1 0 PPP4R2 Pox_RNA_Pol_19 PF05320.7 EIW65694.1 - 2.6 7.7 8.0 3.5 7.3 5.5 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TFIIF_alpha PF05793.7 EIW65694.1 - 2.7 6.2 10.7 3.2 6.0 7.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM176 PF14851.1 EIW65694.1 - 3.2 7.4 6.9 4.4 6.9 4.8 1.1 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 EIW65694.1 - 4.2 7.6 19.9 6.6 7.0 13.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2890 PF11081.3 EIW65694.1 - 5.1 7.0 10.9 6.8 6.7 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) COPI_C PF06957.6 EIW65694.1 - 5.5 5.4 8.5 6.7 5.1 5.9 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Pox_Ag35 PF03286.9 EIW65694.1 - 5.6 6.4 6.3 7.3 6.0 4.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.11 EIW65694.1 - 5.8 5.8 9.0 7.4 5.4 6.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prp19_bind PF06991.6 EIW65694.1 - 9.6 5.3 14.6 13 4.9 10.1 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Myosin_head PF00063.16 EIW65696.1 - 4.4e-16 58.0 3.7 3.3e-07 28.7 0.1 3.3 3 0 0 3 3 3 3 Myosin head (motor domain) AAA_22 PF13401.1 EIW65696.1 - 0.00057 20.0 0.1 0.0045 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIW65696.1 - 0.0022 17.1 0.3 0.012 14.8 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 EIW65696.1 - 0.0024 17.5 0.0 0.006 16.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EIW65696.1 - 0.0052 16.6 0.1 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIW65696.1 - 0.009 15.1 0.2 0.058 12.4 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.18 EIW65696.1 - 0.028 14.2 16.0 0.086 12.6 1.2 4.2 4 1 0 4 4 4 0 Dynamin family RNA_helicase PF00910.17 EIW65696.1 - 0.05 13.7 0.0 0.48 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase FancD2 PF14631.1 EIW65696.1 - 0.14 9.1 3.8 0.38 7.8 0.4 2.1 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease PBP1_TM PF14812.1 EIW65696.1 - 2.4 8.5 31.4 0.16 12.2 1.9 4.3 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 EIW65697.1 - 0.0037 16.0 12.2 0.0037 16.0 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EIW65697.1 - 0.013 15.0 4.8 0.013 15.0 3.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin Cwf_Cwc_15 PF04889.7 EIW65697.1 - 0.042 13.5 7.6 0.052 13.2 5.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 EIW65697.1 - 0.053 12.0 5.0 0.062 11.7 3.5 1.0 1 0 0 1 1 1 0 Daxx Family FLO_LFY PF01698.11 EIW65697.1 - 0.15 10.9 1.8 0.19 10.5 1.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Sigma70_ner PF04546.8 EIW65697.1 - 0.45 10.0 7.2 0.58 9.7 5.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 EIW65697.1 - 1.1 9.0 6.4 1.2 8.8 4.4 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 EIW65697.1 - 1.6 7.9 12.9 1.8 7.7 8.9 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2076 PF09849.4 EIW65697.1 - 2.2 8.3 15.7 2.6 8.0 10.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SDA1 PF05285.7 EIW65697.1 - 2.2 7.5 9.8 2.6 7.2 6.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EIW65697.1 - 3.9 5.2 9.0 3.8 5.3 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family Baculo_PEP_C PF04513.7 EIW65698.1 - 5.4e-05 23.0 1.7 9.2e-05 22.2 1.2 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.1 EIW65698.1 - 0.0018 18.3 1.4 0.0034 17.4 0.2 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 EIW65698.1 - 0.011 15.9 3.0 0.044 14.0 0.5 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3422 PF11902.3 EIW65698.1 - 0.021 13.6 0.2 0.029 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) ADIP PF11559.3 EIW65698.1 - 0.037 13.9 1.1 0.054 13.3 0.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Vip3A_N PF12495.3 EIW65698.1 - 0.038 13.6 0.5 0.057 13.0 0.3 1.3 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal FliD_C PF07195.7 EIW65698.1 - 0.052 12.8 2.4 0.15 11.3 0.5 1.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Bacillus_HBL PF05791.6 EIW65698.1 - 0.079 12.3 1.3 0.11 11.8 0.9 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Nup54 PF13874.1 EIW65698.1 - 0.094 12.3 1.0 0.15 11.7 0.7 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF1664 PF07889.7 EIW65698.1 - 0.11 12.3 2.3 0.39 10.5 1.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3552 PF12072.3 EIW65698.1 - 0.12 11.6 0.4 0.17 11.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF948 PF06103.6 EIW65698.1 - 0.17 11.7 1.2 0.32 10.8 0.8 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.1 EIW65698.1 - 0.38 11.0 3.0 18 5.7 0.1 2.4 1 1 1 2 2 2 0 Snapin/Pallidin Noelin-1 PF12308.3 EIW65698.1 - 0.72 9.6 2.7 0.97 9.2 1.3 1.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein Myosin_head PF00063.16 EIW65700.1 - 3e-19 68.5 0.1 3.1e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) DUF2715 PF10895.3 EIW65704.1 - 0.005 16.3 0.1 0.0066 15.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2715) KRTAP PF11759.3 EIW65704.1 - 0.16 12.2 1.9 0.26 11.5 1.3 1.4 1 0 0 1 1 1 0 Keratin-associated matrix PBP1_TM PF14812.1 EIW65705.1 - 0.036 14.3 1.8 0.036 14.3 1.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTV_NS2 PF04514.7 EIW65705.1 - 0.041 12.7 2.3 0.042 12.7 1.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Spb1_C PF07780.7 EIW65705.1 - 1.2 8.5 4.1 3.2 7.1 2.9 1.7 1 1 0 1 1 1 0 Spb1 C-terminal domain Sigma70_ner PF04546.8 EIW65706.1 - 1.1 8.8 4.8 0.41 10.2 1.0 1.9 1 1 1 2 2 2 0 Sigma-70, non-essential region DUF2360 PF10152.4 EIW65708.1 - 0.025 14.8 2.5 0.041 14.1 1.7 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Mito_fiss_reg PF05308.6 EIW65708.1 - 1 8.6 9.6 0.29 10.4 4.2 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator Cytochrome_C7 PF14522.1 EIW65711.1 - 0.00073 19.1 1.8 0.0014 18.2 0.7 1.8 1 1 1 2 2 2 2 Cytochrome c7 PH_6 PF15406.1 EIW65711.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Cytochrom_c3_2 PF14537.1 EIW65711.1 - 0.039 14.3 4.6 0.054 13.8 2.4 1.9 2 0 0 2 2 2 0 Cytochrome c3 PBP1_TM PF14812.1 EIW65711.1 - 2.1 8.7 12.1 0.48 10.7 5.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal V_ATPase_I PF01496.14 EIW65713.1 - 0.012 13.5 1.5 0.016 13.1 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1317 PF07026.6 EIW65713.1 - 0.027 14.3 0.3 14 5.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1317) DUF4472 PF14739.1 EIW65713.1 - 0.033 14.6 5.2 0.058 13.8 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Cast PF10174.4 EIW65713.1 - 0.097 10.7 9.9 0.13 10.2 6.9 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Periviscerokin PF08259.6 EIW65713.1 - 0.95 9.7 3.5 61 4.2 0.1 3.9 4 0 0 4 4 4 0 Periviscerokinin family ADIP PF11559.3 EIW65713.1 - 1 9.2 9.5 0.2 11.5 3.8 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 EIW65713.1 - 3.1 7.7 8.8 28 4.6 0.2 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.1 EIW65713.1 - 3.5 7.6 15.6 2.7 7.9 7.4 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.16 EIW65713.1 - 9.3 6.3 12.6 8.1 6.4 1.4 3.9 2 1 2 4 4 4 0 bZIP transcription factor Pentapeptide_4 PF13599.1 EIW65714.1 - 0.014 15.2 0.0 0.26 11.1 0.0 2.6 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) WI12 PF07107.6 EIW65714.1 - 0.1 12.4 18.6 0.6 10.0 0.3 4.8 1 1 2 3 3 3 0 Wound-induced protein WI12 SSP160 PF06933.6 EIW65716.1 - 0.0021 16.1 6.4 0.0021 16.1 4.5 1.4 2 0 0 2 2 2 1 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EIW65716.1 - 0.1 12.3 16.7 0.18 11.5 11.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 EIW65716.1 - 0.39 10.4 12.7 0.69 9.6 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EIW65716.1 - 7.6 4.1 6.5 11 3.6 4.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Myc_N PF01056.13 EIW65719.1 - 0.00036 19.8 2.1 0.00068 18.8 1.5 1.5 1 0 0 1 1 1 1 Myc amino-terminal region Nucleoplasmin PF03066.10 EIW65719.1 - 0.012 15.1 1.2 0.012 15.1 0.8 1.8 2 0 0 2 2 2 0 Nucleoplasmin ApoB100_C PF12491.3 EIW65719.1 - 0.024 14.2 0.1 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal Saw1 PF11561.3 EIW65719.1 - 0.037 13.4 1.0 0.066 12.5 0.6 1.4 1 1 0 1 1 1 0 Single strand annealing-weakened 1 Ribosomal_60s PF00428.14 EIW65719.1 - 0.2 12.1 8.3 0.38 11.1 5.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 EIW65719.1 - 8.5 6.7 9.6 2.7 8.3 2.5 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myosin_head PF00063.16 EIW65720.1 - 1e-13 50.2 0.0 4.3e-07 28.3 0.0 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) T2SE PF00437.15 EIW65720.1 - 0.0023 16.8 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EIW65720.1 - 0.028 14.1 0.2 0.18 11.5 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EIW65720.1 - 0.03 14.4 0.1 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW65720.1 - 0.05 12.7 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.10 EIW65720.1 - 0.054 13.3 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EIW65720.1 - 0.086 12.4 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 EIW65720.1 - 0.1 12.0 0.1 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Myosin_head PF00063.16 EIW65721.1 - 7.2e-09 34.2 10.7 4.1e-07 28.4 0.1 3.5 4 0 0 4 4 4 3 Myosin head (motor domain) DUF2315 PF10231.4 EIW65724.1 - 5.5e-08 32.7 8.1 8.1e-05 22.5 3.7 2.4 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2315) BUD22 PF09073.5 EIW65725.1 - 4.8e-66 223.6 10.6 4.8e-66 223.6 7.4 1.9 2 0 0 2 2 2 1 BUD22 Aldedh PF00171.17 EIW65726.1 - 4.1e-98 328.6 0.0 5e-98 328.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_L14 PF00238.14 EIW65727.1 - 6.8e-33 113.0 0.0 7.8e-33 112.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Abi PF02517.11 EIW65728.1 - 1.3e-13 50.8 3.0 7.9e-13 48.3 1.2 2.5 2 1 0 2 2 2 1 CAAX protease self-immunity bZIP_1 PF00170.16 EIW65729.1 - 0.013 15.4 7.7 0.18 11.7 1.3 2.9 2 0 0 2 2 2 0 bZIP transcription factor DUF2383 PF09537.5 EIW65729.1 - 0.089 13.0 2.5 0.64 10.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) Exonuc_VII_S PF02609.11 EIW65729.1 - 0.19 11.5 0.1 0.19 11.5 0.1 2.6 4 0 0 4 4 4 0 Exonuclease VII small subunit FlaC_arch PF05377.6 EIW65729.1 - 1.2 9.0 6.0 4.6 7.2 1.3 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 EIW65729.1 - 1.3 8.6 13.6 0.23 10.9 5.0 2.4 2 0 0 2 2 2 0 Septum formation initiator Hormone_1 PF00103.15 EIW65729.1 - 1.9 7.7 8.7 2.4 7.4 0.1 3.1 2 1 1 3 3 3 0 Somatotropin hormone family DUF972 PF06156.8 EIW65729.1 - 3.2 8.1 14.4 0.33 11.3 1.5 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EIW65729.1 - 3.7 7.9 13.8 7 7.0 1.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Ax_dynein_light PF10211.4 EIW65729.1 - 4.6 7.0 12.7 1.6 8.5 3.6 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain TMF_DNA_bd PF12329.3 EIW65729.1 - 5.8 6.7 13.7 11 5.9 3.9 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 EIW65729.1 - 6.6 6.4 11.8 3.6 7.3 0.9 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 EIW65729.1 - 8.5 5.9 9.2 1.8 8.1 3.1 2.2 1 1 1 2 2 2 0 IncA protein DUF974 PF06159.8 EIW65730.1 - 5.5e-29 101.3 0.0 1.6e-27 96.5 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF974) Citrate_synt PF00285.16 EIW65731.1 - 9.4e-98 327.2 0.0 1.1e-97 326.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase eRF1_1 PF03463.10 EIW65732.1 - 7.9e-49 164.6 0.1 1.7e-48 163.5 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EIW65732.1 - 6.8e-27 94.4 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EIW65732.1 - 2.1e-22 79.5 0.0 4.1e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Kei1 PF08552.6 EIW65733.1 - 5.9e-45 153.2 4.0 7.3e-45 152.9 2.8 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF2417 PF10329.4 EIW65733.1 - 0.29 10.5 3.7 0.5 9.7 2.5 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) RDD PF06271.7 EIW65733.1 - 2.7 7.8 11.3 21 5.0 7.8 2.1 1 1 0 1 1 1 0 RDD family Ribosomal_S3_C PF00189.15 EIW65734.1 - 1.4e-16 60.4 0.0 2.8e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EIW65734.1 - 3.1e-10 39.4 0.0 5.8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EIW65734.1 - 0.02 15.1 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 ERG4_ERG24 PF01222.12 EIW65735.1 - 4.5e-133 443.9 3.6 5e-133 443.7 2.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EIW65735.1 - 4.6e-07 29.3 0.4 3.4e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EIW65735.1 - 4e-05 23.6 0.0 0.0004 20.4 0.0 2.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EIW65735.1 - 0.066 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF3317 PF11779.3 EIW65736.1 - 1.6e-13 49.8 2.7 2.2e-13 49.4 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Iso_dh PF00180.15 EIW65737.1 - 7.7e-69 232.2 0.0 9.5e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HAT PF02184.11 EIW65738.1 - 2.3e-25 88.0 52.5 1e-08 34.7 0.3 13.9 14 1 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EIW65738.1 - 1.3e-23 81.2 29.3 0.00042 20.7 0.0 12.7 4 3 10 14 14 13 6 Tetratricopeptide repeat TPR_19 PF14559.1 EIW65738.1 - 1.4e-16 60.5 2.3 0.00025 21.3 0.0 6.9 4 2 2 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW65738.1 - 7e-14 52.0 25.3 0.00013 22.5 0.1 8.6 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW65738.1 - 3.3e-13 48.4 14.9 0.0061 16.3 0.0 8.9 11 0 0 11 11 8 3 Tetratricopeptide repeat Suf PF05843.9 EIW65738.1 - 9.9e-11 41.8 21.8 0.00035 20.4 0.5 6.6 5 2 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EIW65738.1 - 8.1e-09 35.0 8.6 0.02 14.5 0.0 7.3 5 3 5 10 10 10 2 TPR repeat TPR_7 PF13176.1 EIW65738.1 - 1.5e-08 33.7 10.6 0.096 12.5 0.0 8.5 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW65738.1 - 1.1e-07 31.1 0.8 5.4 6.7 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW65738.1 - 1.9e-07 30.7 1.2 4.9 7.6 0.1 7.0 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW65738.1 - 7e-07 28.5 0.0 0.45 10.3 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW65738.1 - 7.5e-07 28.9 12.5 0.53 10.2 0.0 7.8 5 3 1 7 7 7 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EIW65738.1 - 3.1e-06 26.9 18.8 0.012 15.4 0.7 6.5 6 1 0 6 6 6 3 Mad3/BUB1 homology region 1 TPR_15 PF13429.1 EIW65738.1 - 7.4e-05 21.9 21.3 0.22 10.5 0.1 5.6 2 2 2 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIW65738.1 - 0.0074 16.1 2.5 29 4.6 0.0 5.1 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat DUF3836 PF12930.2 EIW65738.1 - 0.46 9.9 6.0 2.7 7.5 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF3836) TPR_6 PF13174.1 EIW65738.1 - 1.3 9.6 21.9 43 4.8 0.0 9.1 10 1 1 11 11 10 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EIW65738.1 - 1.9 8.3 15.4 0.3 10.8 0.4 5.6 5 2 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 c-SKI_SMAD_bind PF08782.5 EIW65738.1 - 2.2 8.4 5.1 4.6 7.4 0.1 3.6 4 0 0 4 4 4 0 c-SKI Smad4 binding domain FAD-oxidase_C PF02913.14 EIW65740.1 - 2.5e-56 190.7 0.0 3.8e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIW65740.1 - 6.1e-34 116.4 0.1 1.8e-33 114.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain TRAPPC-Trs85 PF12739.2 EIW65740.1 - 0.027 13.1 0.0 0.069 11.7 0.0 1.6 2 0 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Ribosomal_L11_N PF03946.9 EIW65741.1 - 4.4e-18 64.4 0.1 7e-18 63.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EIW65741.1 - 1.9e-12 47.1 0.3 3.2e-12 46.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain WD40 PF00400.27 EIW65742.1 - 1.4e-16 59.6 6.1 1.1e-07 31.4 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIW65742.1 - 0.077 11.7 0.1 0.17 10.5 0.0 1.5 1 0 0 1 1 1 0 Nup133 N terminal like Epimerase PF01370.16 EIW65743.1 - 6.5e-60 202.4 0.0 8.1e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW65743.1 - 3.5e-06 26.1 0.0 4.2e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF4589 PF15252.1 EIW65744.1 - 0.07 12.9 4.8 0.1 12.3 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Phage_holin_1 PF04531.8 EIW65744.1 - 0.13 12.3 0.8 0.34 10.9 0.2 2.0 1 1 0 1 1 1 0 Bacteriophage holin Annexin PF00191.15 EIW65745.1 - 6.5e-58 192.5 0.1 2.3e-14 53.0 0.0 4.2 4 0 0 4 4 4 4 Annexin PITH PF06201.8 EIW65746.1 - 3.3e-37 127.5 0.0 4.2e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain Baculo_PEP_C PF04513.7 EIW65747.1 - 0.002 17.9 0.5 0.0041 16.9 0.3 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EIW65747.1 - 0.061 13.5 1.3 0.18 12.0 0.3 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CorA PF01544.13 EIW65747.1 - 0.15 11.1 0.1 0.33 9.9 0.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2746 PF10874.3 EIW65747.1 - 0.33 11.1 3.9 1.5 9.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) DUF1664 PF07889.7 EIW65747.1 - 0.35 10.6 2.4 0.59 9.9 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1515 PF07439.6 EIW65747.1 - 0.36 10.6 1.7 2.1 8.2 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) SSFA2_C PF14723.1 EIW65747.1 - 0.49 10.1 5.5 0.45 10.2 0.3 2.4 1 1 1 2 2 2 0 Sperm-specific antigen 2 C-terminus MBOAT PF03062.14 EIW65751.1 - 1.2e-47 162.6 22.0 3.5e-47 161.0 15.3 1.8 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Gti1_Pac2 PF09729.4 EIW65752.1 - 3.3e-30 105.1 0.8 1.5e-27 96.5 0.0 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family Cyto_heme_lyase PF01265.12 EIW65754.1 - 1.4e-63 214.9 0.1 1.7e-63 214.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase FLO_LFY PF01698.11 EIW65755.1 - 1.5 7.6 3.0 2.5 6.8 2.1 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein P5CR_dimer PF14748.1 EIW65757.1 - 1.3e-36 124.8 1.3 2.2e-36 124.1 0.9 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EIW65757.1 - 3e-11 43.5 0.1 2.3e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EIW65758.1 - 8.6e-24 83.7 0.0 1.3e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EIW65758.1 - 8.5e-18 63.4 0.2 2.6e-17 61.8 0.2 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EIW65758.1 - 9.7e-09 34.0 0.0 2.6e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central CTP_transf_2 PF01467.21 EIW65759.1 - 2.4e-28 99.1 0.0 2.9e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase UBX PF00789.15 EIW65761.1 - 0.00047 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF2914 PF11141.3 EIW65761.1 - 0.086 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) DUF4338 PF14236.1 EIW65761.1 - 0.47 9.0 3.1 0.63 8.6 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) DUF500 PF04366.7 EIW65762.1 - 2.3e-40 136.9 0.5 3.5e-40 136.3 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EIW65762.1 - 2.1e-14 52.5 0.2 4.8e-14 51.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW65762.1 - 1.8e-11 43.4 0.3 4.9e-11 42.0 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW65762.1 - 4.2e-10 38.9 0.2 8.4e-10 37.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain G-gamma PF00631.17 EIW65764.1 - 1.1e-18 66.7 0.0 1.2e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 GGL domain Prp18 PF02840.10 EIW65765.1 - 1.1e-52 177.7 0.1 1.1e-52 177.7 0.1 2.2 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 EIW65765.1 - 7.6e-13 47.4 4.3 2e-12 46.1 3.0 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like NaeI PF09126.5 EIW65765.1 - 0.033 12.8 1.4 0.038 12.6 0.0 1.8 3 0 0 3 3 3 0 Restriction endonuclease NaeI DUF4544 PF15077.1 EIW65765.1 - 0.5 9.8 4.1 0.69 9.3 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4544) Mre11_DNA_bind PF04152.9 EIW65765.1 - 0.81 9.5 7.4 0.044 13.6 1.2 1.8 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain DEAD PF00270.24 EIW65766.1 - 1.1e-47 161.6 0.0 1.7e-46 157.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW65766.1 - 6.9e-27 93.1 0.1 2e-26 91.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW65766.1 - 2.4e-05 24.2 0.0 0.00012 22.0 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EIW65766.1 - 0.0027 16.1 0.0 0.033 12.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 EIW65766.1 - 0.0059 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain RGS-like PF09128.6 EIW65766.1 - 0.13 11.7 0.1 0.26 10.7 0.0 1.4 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain Lactamase_B_2 PF12706.2 EIW65767.1 - 3.7e-34 117.9 0.2 6.4e-34 117.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIW65767.1 - 2.1e-15 56.8 0.0 2.8e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIW65767.1 - 0.017 14.8 0.2 0.058 13.0 0.0 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily IF4E PF01652.13 EIW65768.1 - 3.2e-31 108.0 0.0 5.6e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RRM_1 PF00076.17 EIW65769.1 - 3.9e-27 93.6 0.8 1.5e-13 50.1 0.0 4.9 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW65769.1 - 2e-22 78.9 0.0 1e-07 31.8 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW65769.1 - 9.9e-14 50.9 0.1 0.003 17.3 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_2 PF07992.9 EIW65770.1 - 2.1e-32 112.6 0.1 2.6e-32 112.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW65770.1 - 1.4e-17 63.8 0.3 1.3e-14 54.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW65770.1 - 9e-10 38.9 0.0 2.9e-06 27.4 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW65770.1 - 5.6e-06 25.4 3.3 0.0052 15.6 0.1 4.0 4 0 0 4 4 4 1 Glucose inhibited division protein A Thi4 PF01946.12 EIW65770.1 - 5.7e-06 25.5 0.1 7.3e-05 21.9 0.0 2.5 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 EIW65770.1 - 8.4e-06 24.9 0.5 0.017 14.0 0.1 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW65770.1 - 3e-05 23.9 0.1 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EIW65770.1 - 0.00019 21.6 0.0 0.041 14.1 0.0 2.8 2 2 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EIW65770.1 - 0.00023 21.2 0.1 0.24 11.5 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 EIW65770.1 - 0.00027 19.9 0.0 0.1 11.5 0.0 3.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 EIW65770.1 - 0.00043 19.4 0.6 0.092 11.8 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW65770.1 - 0.00063 18.9 0.6 0.052 12.5 0.0 2.9 2 1 1 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.19 EIW65770.1 - 0.0014 17.6 1.0 0.0087 14.9 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIW65770.1 - 0.0022 16.5 0.2 0.02 13.3 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein Trp_halogenase PF04820.9 EIW65770.1 - 0.01 14.5 0.2 0.052 12.1 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EIW65770.1 - 0.025 14.3 0.3 11 5.8 0.0 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EIW65770.1 - 0.027 14.2 0.1 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EIW65770.1 - 0.034 14.5 0.1 4.2 7.8 0.0 2.9 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EIW65770.1 - 0.061 12.7 0.4 12 5.3 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 EIW65770.1 - 0.092 12.1 0.0 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain TFIIS_M PF07500.9 EIW65771.1 - 7.5e-26 90.4 0.9 7.5e-26 90.4 0.7 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 EIW65771.1 - 2.7e-12 45.9 0.1 4.9e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_C PF01096.13 EIW65771.1 - 1.4e-10 40.5 9.8 4.2e-10 39.0 6.8 1.8 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS) Glycoprotein_G PF00802.14 EIW65772.1 - 0.064 12.3 1.3 0.08 12.0 0.9 1.1 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G TPD52 PF04201.10 EIW65774.1 - 0.026 14.2 0.3 0.038 13.7 0.2 1.2 1 0 0 1 1 1 0 Tumour protein D52 family p450 PF00067.17 EIW65778.1 - 5.5e-65 219.6 0.0 1.2e-64 218.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 RHH_2 PF03693.9 EIW65778.1 - 0.024 14.7 0.1 0.066 13.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0156) zf-Tim10_DDP PF02953.10 EIW65779.1 - 7e-13 47.6 0.4 1.3e-12 46.8 0.3 1.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF1754 PF08555.5 EIW65780.1 - 2.1e-06 28.2 9.1 2.1e-06 28.2 6.3 1.6 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Hat1_N PF10394.4 EIW65780.1 - 0.04 13.9 1.8 0.047 13.7 1.3 1.3 1 1 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus Pet20 PF08692.5 EIW65780.1 - 0.23 11.4 2.7 0.14 12.0 0.2 1.7 1 1 1 2 2 2 0 Mitochondrial protein Pet20 DUF4407 PF14362.1 EIW65780.1 - 0.45 9.4 3.1 0.63 8.9 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1068 PF06364.7 EIW65780.1 - 1.2 8.7 5.0 0.14 11.7 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) DUF3713 PF12506.3 EIW65780.1 - 3.4 7.7 7.3 0.68 10.0 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) UQ_con PF00179.21 EIW65781.1 - 6.5e-20 70.9 0.0 1.2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EIW65781.1 - 0.0059 16.2 0.1 0.05 13.2 0.0 2.3 2 0 0 2 2 2 1 UEV domain Abhydrolase_5 PF12695.2 EIW65782.1 - 6.1e-08 32.5 0.0 1.1e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW65782.1 - 0.0023 17.8 0.0 0.0041 17.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIW65782.1 - 0.15 11.4 0.0 0.51 9.7 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Dynein_light PF01221.13 EIW65783.1 - 2.7e-40 136.2 1.7 3.2e-40 136.0 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF2891 PF11199.3 EIW65783.1 - 0.13 10.8 0.0 0.13 10.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) MRG PF05712.8 EIW65784.1 - 2e-52 176.9 0.6 2.9e-52 176.4 0.4 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EIW65784.1 - 1.5e-07 31.0 0.1 3.5e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EIW65784.1 - 0.057 13.1 0.3 0.17 11.5 0.2 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2_2 PF13465.1 EIW65785.1 - 1.2e-06 28.5 11.3 5.2e-06 26.4 0.1 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIW65785.1 - 7.5e-06 25.9 12.4 0.0019 18.4 0.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW65785.1 - 8.7e-05 22.5 17.6 0.0024 18.0 1.8 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EIW65785.1 - 0.19 11.9 1.4 0.38 11.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EIW65785.1 - 5.5 7.4 17.6 0.8 10.0 0.2 3.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain DUF1279 PF06916.8 EIW65786.1 - 1.3e-19 70.3 0.0 2.4e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Trypan_PARP PF05887.6 EIW65786.1 - 1.3 8.7 6.4 0.18 11.6 0.4 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ras PF00071.17 EIW65787.1 - 2e-51 173.5 0.0 2.3e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW65787.1 - 1.2e-18 67.7 0.0 1.7e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW65787.1 - 8e-06 25.2 0.0 9.5e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ferritin_2 PF13668.1 EIW65788.1 - 4.4e-43 146.5 0.1 6.7e-43 145.9 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Spherulin4 PF12138.3 EIW65788.1 - 0.043 13.2 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Spherulation-specific family 4 Gly_transf_sug PF04488.10 EIW65789.1 - 4.2e-09 36.7 0.1 1.1e-08 35.3 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif 2OG-FeII_Oxy_3 PF13640.1 EIW65790.1 - 1.7e-07 31.7 0.0 2.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EIW65790.1 - 0.059 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Heme_oxygenase PF01126.15 EIW65791.1 - 8.7e-33 113.6 0.0 2.2e-18 66.5 0.0 2.1 2 0 0 2 2 2 2 Heme oxygenase COX6B PF02297.12 EIW65795.1 - 4.6e-12 45.7 4.5 5.4e-12 45.5 3.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EIW65795.1 - 0.01 15.7 0.4 0.021 14.7 0.3 1.6 1 1 0 1 1 1 0 CHCH domain DUF59 PF01883.14 EIW65796.1 - 3.4e-12 46.1 0.1 8.9e-12 44.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF59 PIG-H PF10181.4 EIW65799.1 - 4e-15 55.2 0.1 8.7e-15 54.1 0.1 1.6 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component RhoGAP PF00620.22 EIW65802.1 - 3.3e-48 163.1 0.0 6.1e-48 162.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EIW65802.1 - 1.8e-11 44.0 0.0 6.9e-11 42.1 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain IF3_C PF00707.17 EIW65803.1 - 0.00071 19.2 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EIW65803.1 - 0.005 16.2 1.3 0.0075 15.6 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial translation initiation factor CCDC50_N PF15295.1 EIW65803.1 - 0.0098 15.8 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus Metallophos_2 PF12850.2 EIW65804.1 - 2.9e-10 40.1 0.0 4.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIW65804.1 - 4.8e-09 35.9 0.6 8.5e-09 35.0 0.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EIW65804.1 - 0.024 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily UDPGT PF00201.13 EIW65805.1 - 1.7e-12 46.6 0.0 2.6e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EIW65805.1 - 0.00057 19.1 0.0 0.00097 18.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EIW65805.1 - 0.031 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Proteasome PF00227.21 EIW65807.1 - 5.1e-33 113.9 0.0 9.1e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit GAPT PF11770.3 EIW65808.1 - 0.013 15.2 0.3 0.031 13.9 0.2 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) MAGE PF01454.14 EIW65809.1 - 3.4e-39 134.2 0.0 5.2e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 MAGE family AA_permease_N PF08403.5 EIW65809.1 - 0.022 14.0 0.1 0.062 12.6 0.1 1.7 1 0 0 1 1 1 0 Amino acid permease N-terminal DUF4557 PF15101.1 EIW65809.1 - 4.7 6.9 6.6 0.73 9.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) RNase_PH PF01138.16 EIW65810.1 - 2.2e-11 44.1 0.0 3.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Atg8 PF02991.11 EIW65812.1 - 1.9e-51 172.3 0.2 2.2e-51 172.1 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EIW65812.1 - 1.4e-06 28.4 0.0 1.7e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Polysacc_deac_1 PF01522.16 EIW65813.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.16 EIW65814.1 - 0.00043 19.9 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase Brix PF04427.13 EIW65815.1 - 1.9e-35 122.3 0.3 2.6e-35 121.8 0.2 1.2 1 0 0 1 1 1 1 Brix domain Csm1 PF12539.3 EIW65816.1 - 0.0045 17.4 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 TPR_MLP1_2 PF07926.7 EIW65816.1 - 0.041 13.6 11.7 0.74 9.5 2.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YPEB PF14620.1 EIW65816.1 - 0.049 12.6 6.6 0.078 11.9 4.6 1.4 1 1 0 1 1 1 0 YpeB sporulation Atg14 PF10186.4 EIW65816.1 - 0.063 12.2 9.3 0.4 9.5 0.2 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMEM192 PF14802.1 EIW65816.1 - 0.085 11.7 0.3 0.12 11.2 0.2 1.2 1 0 0 1 1 1 0 TMEM192 family ATG16 PF08614.6 EIW65816.1 - 0.11 12.2 19.3 0.44 10.3 4.0 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Spc24 PF08286.6 EIW65816.1 - 0.16 11.6 9.5 0.21 11.3 2.8 2.7 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.5 EIW65816.1 - 0.19 11.8 3.0 4.4 7.4 0.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.1 EIW65816.1 - 0.25 10.2 10.2 0.071 12.0 4.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Filament PF00038.16 EIW65816.1 - 0.32 10.4 13.6 0.49 9.8 1.6 2.1 2 0 0 2 2 2 0 Intermediate filament protein DUF3138 PF11336.3 EIW65816.1 - 0.47 8.5 1.9 0.55 8.3 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) GAS PF13851.1 EIW65816.1 - 0.5 9.5 12.3 1.1 8.3 2.4 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF713 PF05218.9 EIW65816.1 - 0.59 9.8 7.0 0.13 11.9 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF713) Mnd1 PF03962.10 EIW65816.1 - 0.83 9.2 16.1 1.1 8.8 3.9 2.2 2 0 0 2 2 2 0 Mnd1 family Fez1 PF06818.10 EIW65816.1 - 1.2 9.0 12.1 0.71 9.8 1.2 2.2 2 0 0 2 2 2 0 Fez1 bZIP_1 PF00170.16 EIW65816.1 - 1.6 8.7 12.9 1.3 9.0 0.8 3.5 2 2 1 3 3 3 0 bZIP transcription factor DivIC PF04977.10 EIW65816.1 - 2.8 7.5 16.9 0.47 9.9 4.3 3.0 3 0 0 3 3 3 0 Septum formation initiator ADIP PF11559.3 EIW65816.1 - 4.7 7.1 16.6 0.91 9.4 3.8 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.8 EIW65816.1 - 6.2 5.7 7.1 1.6 7.7 0.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein VHS PF00790.14 EIW65817.1 - 5.2e-33 113.6 0.0 9.7e-33 112.7 0.0 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EIW65817.1 - 1.6e-12 46.6 0.0 2.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIW65817.1 - 1e-11 44.1 0.1 1.9e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIW65817.1 - 1.7e-09 37.0 0.1 3.2e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EIW65817.1 - 0.0021 17.4 1.5 0.0078 15.7 1.0 2.1 1 0 0 1 1 1 1 Ubiquitin interaction motif GAT PF03127.9 EIW65817.1 - 0.0047 16.8 3.0 0.0065 16.4 0.2 2.4 3 0 0 3 3 3 1 GAT domain HEAT_2 PF13646.1 EIW65817.1 - 0.017 15.3 0.7 0.064 13.5 0.5 2.1 1 1 0 1 1 1 0 HEAT repeats Vault PF01505.13 EIW65817.1 - 0.049 13.6 1.2 0.65 10.0 0.0 2.9 3 0 0 3 3 3 0 Major Vault Protein repeat SAS4 PF15460.1 EIW65817.1 - 0.56 10.1 3.9 3.2 7.6 0.1 2.9 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 DUF3128 PF11326.3 EIW65818.1 - 2.8e-23 81.8 0.4 3.7e-23 81.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) GAGA PF09237.6 EIW65818.1 - 0.0032 17.0 0.1 0.0058 16.2 0.1 1.4 1 0 0 1 1 1 1 GAGA factor WD40 PF00400.27 EIW65819.1 - 7.5e-17 60.5 16.6 5.5e-08 32.4 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF2788 PF10981.3 EIW65819.1 - 0.003 17.3 0.2 0.0051 16.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2788) Rax2 PF12768.2 EIW65819.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DPPIV_N PF00930.16 EIW65819.1 - 0.026 13.1 1.5 0.27 9.7 0.4 2.8 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 EIW65819.1 - 0.026 14.2 0.2 0.8 9.3 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Vps16_N PF04841.8 EIW65819.1 - 0.07 11.6 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region Na_H_Exchanger PF00999.16 EIW65820.1 - 3.5e-61 206.8 44.4 5.2e-61 206.2 30.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp PF00026.18 EIW65821.1 - 1e-76 258.2 12.1 1.2e-76 258.0 8.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW65821.1 - 6.9e-11 42.3 1.4 8.2e-10 38.8 1.2 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Adeno_PIX PF03955.9 EIW65822.1 - 0.19 12.2 2.7 6 7.4 0.1 2.9 3 1 0 3 3 3 0 Adenovirus hexon-associated protein (IX) UAA PF08449.6 EIW65823.1 - 2.8e-11 42.8 12.1 3.8e-11 42.4 8.4 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EIW65823.1 - 2e-07 30.7 3.4 2e-07 30.7 2.3 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family GLTSCR1 PF15249.1 EIW65824.1 - 1e-08 35.2 0.0 2.1e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Glioma tumor suppressor candidate region Lzipper-MIP1 PF14389.1 EIW65824.1 - 0.034 14.2 0.2 7.6 6.7 0.0 2.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF2665 PF11654.3 EIW65825.1 - 4.2e-21 74.2 0.1 6.7e-21 73.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) IGR PF09597.5 EIW65826.1 - 1.7e-08 34.2 0.1 7.2e-08 32.2 0.0 2.0 3 0 0 3 3 3 1 IGR protein motif MAT1 PF06391.8 EIW65827.1 - 8.9e-38 129.8 10.8 1.2e-37 129.4 7.5 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 EIW65827.1 - 5.1e-06 26.1 7.5 1.1e-05 25.0 5.3 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW65827.1 - 4.9e-05 22.9 8.0 8.8e-05 22.0 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW65827.1 - 0.00019 21.1 8.3 0.0003 20.5 5.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW65827.1 - 0.00064 19.6 9.3 0.001 19.0 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-FPG_IleRS PF06827.9 EIW65827.1 - 0.11 12.1 0.2 0.11 12.1 0.1 2.7 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DZR PF12773.2 EIW65827.1 - 0.27 11.0 6.3 1.4 8.7 4.3 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 EIW65827.1 - 0.47 10.0 8.1 2.5 7.7 6.0 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 EIW65827.1 - 0.8 9.2 0.1 0.8 9.2 0.0 3.1 4 0 0 4 4 4 0 Rad50 zinc hook motif PX PF00787.19 EIW65828.1 - 2.3e-23 82.1 0.0 2.9e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 PX domain UCH PF00443.24 EIW65829.1 - 1.1e-50 172.2 0.0 1.8e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EIW65829.1 - 8e-26 89.9 15.8 1e-20 73.5 0.9 3.9 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EIW65829.1 - 1.9e-22 78.4 1.8 2.1e-11 43.3 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 EIW65829.1 - 3.4e-21 75.9 0.0 2.7e-20 72.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 EIW65829.1 - 0.032 13.7 0.0 0.087 12.3 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain SNARE_assoc PF09335.6 EIW65830.1 - 1e-11 45.0 5.5 1e-11 45.0 3.8 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein Transgly_assoc PF04226.8 EIW65830.1 - 6.2 6.9 14.0 0.1 12.7 1.2 3.1 3 0 0 3 3 3 0 Transglycosylase associated protein 2-Hacid_dh_C PF02826.14 EIW65831.1 - 2.4e-56 189.7 0.0 2.9e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW65831.1 - 3.1e-13 49.3 0.0 3.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIW65831.1 - 0.0001 22.1 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIW65831.1 - 0.024 15.0 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Asp_Glu_race PF01177.17 EIW65832.1 - 0.058 13.3 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase DAO PF01266.19 EIW65833.1 - 1.5e-45 155.6 0.0 2.3e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW65833.1 - 1e-08 35.3 0.0 0.001 19.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW65833.1 - 1.9e-05 24.5 0.0 4.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIW65833.1 - 8.8e-05 22.3 0.1 0.026 14.3 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EIW65833.1 - 0.00023 21.2 0.0 0.065 13.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EIW65833.1 - 0.00046 20.5 0.0 0.03 14.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW65833.1 - 0.00057 18.8 0.1 0.0054 15.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIW65833.1 - 0.0023 16.4 0.0 0.75 8.1 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EIW65833.1 - 0.0037 17.3 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW65833.1 - 0.0041 16.0 0.1 0.92 8.3 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EIW65833.1 - 0.013 14.5 0.0 0.036 13.1 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.16 EIW65833.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 ThiF family GMC_oxred_N PF00732.14 EIW65833.1 - 0.017 14.2 0.0 0.95 8.5 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Thi4 PF01946.12 EIW65833.1 - 0.024 13.7 0.1 0.045 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 EIW65833.1 - 0.025 14.5 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EIW65833.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EIW65833.1 - 0.073 12.4 0.1 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EIW65833.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UCH PF00443.24 EIW65834.1 - 3.3e-12 46.0 0.0 1.5e-10 40.6 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW65834.1 - 3.5e-09 36.5 0.0 8.2e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Daxx PF03344.10 EIW65834.1 - 0.00082 18.0 28.4 0.00082 18.0 19.7 2.7 3 0 0 3 3 3 1 Daxx Family SWIM PF04434.12 EIW65834.1 - 0.017 14.5 0.9 0.13 11.7 0.3 2.3 2 0 0 2 2 2 0 SWIM zinc finger MULE PF10551.4 EIW65834.1 - 0.039 14.1 0.0 1.7 8.8 0.0 2.8 1 1 0 1 1 1 0 MULE transposase domain GAGA_bind PF06217.7 EIW65835.1 - 0.029 14.3 2.5 0.052 13.5 1.7 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF972 PF06156.8 EIW65835.1 - 1.7 9.0 4.7 5.6 7.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF972) MFS_1 PF07690.11 EIW65836.1 - 1.6e-27 96.1 23.6 2.3e-27 95.6 16.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily EOS1 PF12326.3 EIW65837.1 - 1.3e-21 76.7 4.0 1.9e-21 76.2 1.8 1.8 2 0 0 2 2 2 1 N-glycosylation protein Flavin_Reduct PF01613.13 EIW65839.1 - 3.6e-32 111.3 2.8 1.9e-17 63.5 0.0 2.2 1 1 0 2 2 2 2 Flavin reductase like domain ADH_N PF08240.7 EIW65840.1 - 8.9e-17 60.8 0.9 1.6e-16 59.9 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW65840.1 - 2.4e-16 59.4 0.0 4.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_M50 PF02163.17 EIW65841.1 - 4.2e-14 51.9 0.0 6.1e-12 44.8 0.0 2.5 2 1 0 2 2 2 1 Peptidase family M50 PDZ_2 PF13180.1 EIW65841.1 - 1.9e-05 24.4 0.0 3.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EIW65841.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Yae1_N PF09811.4 EIW65842.1 - 4.5e-07 29.2 8.4 4.5e-07 29.2 5.8 1.9 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Snf7 PF03357.16 EIW65843.1 - 1.5e-47 161.1 12.5 1.6e-47 161.0 8.7 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.15 EIW65843.1 - 0.032 13.9 10.2 0.51 10.1 0.0 3.2 2 1 0 2 2 2 0 Prefoldin subunit Prefoldin PF02996.12 EIW65843.1 - 0.083 12.5 4.6 2 8.0 0.7 3.0 3 0 0 3 3 3 0 Prefoldin subunit FlaC_arch PF05377.6 EIW65843.1 - 0.15 12.0 1.7 4.7 7.1 0.0 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Prominin PF05478.6 EIW65843.1 - 0.26 8.7 3.4 0.32 8.4 2.4 1.2 1 0 0 1 1 1 0 Prominin Mnd1 PF03962.10 EIW65843.1 - 1.4 8.5 10.9 4.6 6.8 7.6 1.8 1 1 0 1 1 1 0 Mnd1 family Phage_GP20 PF06810.6 EIW65843.1 - 2.3 7.6 14.4 1.7 8.0 7.5 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 FlxA PF14282.1 EIW65843.1 - 3.4 7.6 11.1 2.4 8.1 5.3 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF972 PF06156.8 EIW65843.1 - 3.8 7.8 8.2 28 5.0 3.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DDHD PF02862.12 EIW65844.1 - 0.025 14.3 1.0 0.038 13.8 0.7 1.2 1 0 0 1 1 1 0 DDHD domain FGase PF05013.7 EIW65844.1 - 0.082 12.7 0.3 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 N-formylglutamate amidohydrolase IlvN PF07991.7 EIW65845.1 - 3.6e-47 159.8 0.1 7.7e-47 158.7 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EIW65845.1 - 1.3e-42 145.1 0.0 2.1e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EIW65845.1 - 0.062 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Prenyltrans PF00432.16 EIW65846.1 - 3.4e-26 90.4 19.5 2.2e-06 27.1 0.0 6.7 6 1 1 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIW65846.1 - 1.6e-13 51.0 0.0 1.1e-11 45.1 0.0 2.9 2 1 1 3 3 3 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIW65846.1 - 0.014 15.3 0.0 0.28 11.2 0.0 2.9 2 1 1 3 3 3 0 Prenyltransferase-like SGL PF08450.7 EIW65847.1 - 1.7e-61 207.7 0.0 2e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region SH3_1 PF00018.23 EIW65849.1 - 8e-41 137.2 5.8 3.7e-15 55.0 0.1 4.2 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EIW65849.1 - 2.9e-38 129.1 5.9 1e-14 53.7 0.3 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EIW65849.1 - 5.1e-31 105.9 0.2 2e-10 39.9 0.1 4.4 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.7 EIW65849.1 - 9.9e-29 98.8 0.1 7e-28 96.0 0.1 2.2 2 0 0 2 2 2 1 SLA1 homology domain 1, SHD1 DUF1720 PF08226.6 EIW65849.1 - 0.00017 21.5 8.2 0.00017 21.5 5.7 5.1 2 1 2 4 4 4 2 Domain of unknown function (DUF1720) SH3_3 PF08239.6 EIW65849.1 - 0.039 14.1 3.2 3 8.1 0.3 3.3 3 0 0 3 3 3 0 Bacterial SH3 domain DUF155 PF02582.9 EIW65850.1 - 2.4e-48 164.3 0.0 3.4e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 MARVEL PF01284.18 EIW65851.1 - 2.9e-09 36.8 9.2 4.2e-09 36.3 6.2 1.3 1 1 0 1 1 1 1 Membrane-associating domain VSP PF03302.8 EIW65852.1 - 0.00016 20.4 2.5 0.00023 19.9 1.7 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF1517 PF07466.6 EIW65852.1 - 0.22 10.4 1.4 0.37 9.7 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Adeno_E3_CR2 PF02439.10 EIW65852.1 - 0.27 10.8 3.7 0.49 9.9 2.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 BTG PF07742.7 EIW65853.1 - 9.2e-08 31.6 0.1 6.7e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 BTG family IKI3 PF04762.7 EIW65854.1 - 3.5e-220 733.3 0.0 5.5e-220 732.7 0.0 1.3 1 0 0 1 1 1 1 IKI3 family WD40 PF00400.27 EIW65854.1 - 0.0011 18.7 0.2 3.5 7.6 0.0 3.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 EIW65854.1 - 0.012 13.7 0.3 0.027 12.6 0.2 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Clathrin PF00637.15 EIW65854.1 - 2 8.0 5.2 12 5.4 0.0 3.8 3 2 0 4 4 4 0 Region in Clathrin and VPS DUF106 PF01956.11 EIW65855.1 - 4.2e-47 159.8 0.1 6e-47 159.3 0.1 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 Baculo_PEP_C PF04513.7 EIW65856.1 - 0.015 15.0 0.6 0.028 14.2 0.2 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DMRL_synthase PF00885.14 EIW65857.1 - 3.1e-48 163.0 0.1 2.2e-27 95.5 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase 4HBT_2 PF13279.1 EIW65858.1 - 0.0033 17.8 0.0 0.0053 17.2 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily ATP-synt_ab PF00006.20 EIW65860.1 - 3.7e-64 216.1 0.0 6.8e-64 215.3 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIW65860.1 - 2.5e-25 89.1 0.7 4.8e-25 88.2 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIW65860.1 - 2.6e-23 81.9 1.6 7.3e-23 80.5 1.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 EIW65860.1 - 0.002 17.2 0.1 0.004 16.3 0.1 1.5 1 0 0 1 1 1 1 KaiC Arch_ATPase PF01637.13 EIW65860.1 - 0.0038 16.9 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EIW65860.1 - 0.0074 15.7 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW65860.1 - 0.0078 16.2 0.1 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EIW65860.1 - 0.009 15.2 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EIW65860.1 - 0.012 15.2 0.1 0.52 10.0 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EIW65860.1 - 0.018 14.6 0.1 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 EIW65860.1 - 0.021 15.0 0.0 0.24 11.6 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW65860.1 - 0.034 14.2 0.0 0.21 11.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIW65860.1 - 0.06 12.1 0.8 0.13 11.0 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 EIW65860.1 - 0.069 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW65860.1 - 0.083 13.0 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CR6_interact PF10147.4 EIW65861.1 - 0.00039 19.8 0.8 0.00063 19.1 0.5 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 KAR9 PF08580.5 EIW65861.1 - 0.68 8.1 4.9 1.1 7.4 3.4 1.3 1 1 0 1 1 1 0 Yeast cortical protein KAR9 DUF2984 PF11203.3 EIW65862.1 - 0.024 14.7 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) UCR_14kD PF02271.11 EIW65865.1 - 1.8e-37 127.2 0.5 2e-37 127.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit PQ-loop PF04193.9 EIW65866.1 - 3.6e-20 71.2 0.6 2.4e-14 52.6 0.2 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF1903 PF08991.5 EIW65867.1 - 6.7e-06 26.1 3.3 9.4e-06 25.6 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EIW65867.1 - 0.0002 21.1 3.3 0.00027 20.7 2.3 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EIW65867.1 - 0.017 15.1 2.7 0.028 14.4 1.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 EIW65867.1 - 0.024 14.5 4.1 0.06 13.1 2.6 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Clat_adaptor_s PF01217.15 EIW65868.1 - 1.3e-55 187.0 3.1 1.4e-55 186.8 2.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DPPIV_N PF00930.16 EIW65869.1 - 2.2e-92 309.3 1.5 2.2e-92 309.3 1.0 1.5 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EIW65869.1 - 3e-48 163.8 1.9 5.8e-48 162.9 1.3 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW65869.1 - 3.4e-07 30.1 0.0 1e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW65869.1 - 0.00018 21.4 0.0 0.00061 19.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EIW65869.1 - 0.0016 17.7 0.1 0.19 10.8 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_2 PF02230.11 EIW65869.1 - 0.062 12.7 0.0 0.93 8.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase E1-E2_ATPase PF00122.15 EIW65870.1 - 3.2e-49 167.0 2.3 3.2e-49 167.0 1.6 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIW65870.1 - 1.5e-44 152.9 0.0 3e-44 151.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW65870.1 - 4.6e-15 56.2 0.0 9.5e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EIW65870.1 - 1e-08 35.2 0.0 2.4e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EIW65870.1 - 0.0002 21.0 0.3 0.026 14.1 0.4 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Ribosomal_S11 PF00411.14 EIW65871.1 - 6.2e-40 135.8 0.4 7.7e-40 135.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Metallophos PF00149.23 EIW65876.1 - 4e-33 114.5 0.6 4e-33 114.5 0.4 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EIW65876.1 - 5.9e-13 48.6 0.9 1.8e-12 47.1 0.2 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EIW65876.1 - 2.7e-08 32.8 0.2 1.8e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.2 EIW65876.1 - 0.062 13.1 0.0 0.2 11.4 0.0 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Fungal_trans PF04082.13 EIW65878.1 - 1.1e-14 54.0 0.0 1.1e-09 37.5 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW65878.1 - 0.014 15.3 5.6 0.026 14.4 3.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.13 EIW65879.1 - 1.1e-32 113.3 0.1 1.8e-32 112.7 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Gp_dh_C PF02800.15 EIW65880.1 - 1.8e-71 238.6 0.1 2.7e-71 238.0 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EIW65880.1 - 3.4e-60 202.3 0.1 5.9e-60 201.5 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EIW65880.1 - 0.014 15.2 0.3 0.049 13.5 0.1 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus HAD_2 PF13419.1 EIW65881.1 - 7.6e-15 55.5 0.0 6.2e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW65881.1 - 5.7e-11 43.2 0.0 6.2e-10 39.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW65881.1 - 1.8e-08 33.9 0.0 4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EIW65881.1 - 0.047 13.8 0.0 0.063 13.4 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase 7TM_GPCR_Srw PF10324.4 EIW65882.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Pkinase PF00069.20 EIW65883.1 - 1.7e-52 178.1 0.0 2.4e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW65883.1 - 5.8e-24 84.5 0.3 2.7e-23 82.3 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW65883.1 - 0.00027 20.0 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW65883.1 - 0.00064 19.5 0.1 0.14 11.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIW65883.1 - 0.034 13.1 0.1 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIW65883.1 - 0.069 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.27 EIW65884.1 - 1.7e-10 40.3 2.1 1.1 9.2 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF4112 PF13430.1 EIW65885.1 - 1e-12 47.8 0.2 1.8e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) WD40 PF00400.27 EIW65886.1 - 9.2e-37 123.6 13.8 1.9e-06 27.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Transthyretin PF00576.16 EIW65887.1 - 3.2e-36 123.6 0.0 4e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family AraC_N PF06719.8 EIW65887.1 - 0.077 12.2 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus 2-Hacid_dh_C PF02826.14 EIW65888.1 - 5.5e-46 155.9 0.0 7.3e-46 155.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW65888.1 - 2.5e-20 72.3 0.0 2.9e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIW65888.1 - 5.8e-05 22.9 0.0 8.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Uso1_p115_head PF04869.9 EIW65889.1 - 1.4e-83 280.2 0.0 2.6e-83 279.3 0.0 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EIW65889.1 - 0.63 9.9 43.6 0.032 14.1 24.5 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.6 EIW65889.1 - 1.2 7.6 23.0 2 6.9 15.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2968 PF11180.3 EIW65889.1 - 9 5.6 24.9 0.25 10.7 12.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Nnf1 PF03980.9 EIW65891.1 - 8.9e-06 25.6 0.1 1.8e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Nnf1 MAP65_ASE1 PF03999.7 EIW65891.1 - 0.017 13.7 0.1 0.028 13.0 0.1 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) UPF0147 PF03685.8 EIW65891.1 - 0.034 14.0 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) FTA4 PF13093.1 EIW65891.1 - 0.072 12.5 2.2 0.13 11.7 1.5 1.6 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Laminin_EGF PF00053.19 EIW65892.1 - 0.0053 16.6 16.9 0.0053 16.6 11.7 8.4 3 2 2 5 5 5 1 Laminin EGF-like (Domains III and V) CcmD PF04995.9 EIW65892.1 - 0.17 11.6 0.4 0.36 10.6 0.3 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) VSP PF03302.8 EIW65892.1 - 0.72 8.4 143.6 0.049 12.2 8.6 7.1 2 1 5 7 7 7 0 Giardia variant-specific surface protein BSD PF03909.12 EIW65893.1 - 3.9e-15 55.3 0.2 1e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EIW65893.1 - 6.6e-14 51.3 0.0 1.6e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF1662 PF07878.6 EIW65893.1 - 0.082 12.6 0.0 0.33 10.7 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1662) Tropomyosin PF00261.15 EIW65895.1 - 0.063 12.3 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Tropomyosin MT-A70 PF05063.9 EIW65897.1 - 9e-29 100.2 0.0 1.4e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 MT-A70 ADH_zinc_N PF00107.21 EIW65898.1 - 5.8e-21 74.3 0.0 1e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW65898.1 - 1.5e-13 51.7 0.0 2.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW65898.1 - 3.2e-08 33.2 0.2 1.9e-06 27.5 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain YppF PF14178.1 EIW65898.1 - 0.067 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 YppF-like protein Sec63 PF02889.11 EIW65899.1 - 1.8e-39 135.8 0.0 2.6e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EIW65899.1 - 2.7e-23 82.3 0.0 1e-22 80.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW65899.1 - 9.6e-09 34.9 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EIW65899.1 - 0.087 13.0 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain HLH PF00010.21 EIW65900.1 - 2.7e-13 49.3 1.9 3e-13 49.2 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain F-box PF00646.28 EIW65901.1 - 0.0011 18.5 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 EIW65901.1 - 0.0014 18.5 0.1 0.0022 17.8 0.1 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 EIW65901.1 - 0.037 13.9 0.1 0.084 12.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW65901.1 - 0.056 13.0 0.1 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat His_Phos_1 PF00300.17 EIW65902.1 - 1.5e-15 57.5 0.0 1.9e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Maf1 PF09174.5 EIW65902.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Maf1 regulator MAPEG PF01124.13 EIW65903.1 - 2e-08 33.8 1.6 6.8e-08 32.1 0.7 1.9 2 0 0 2 2 2 1 MAPEG family COX15-CtaA PF02628.10 EIW65903.1 - 0.0048 15.8 0.6 0.006 15.4 0.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein GPDPase_memb PF10110.4 EIW65903.1 - 0.053 12.9 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Med10 PF09748.4 EIW65904.1 - 3.1e-14 52.8 0.0 4.2e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex SNARE PF05739.14 EIW65904.1 - 0.11 12.1 1.2 0.27 10.9 0.8 1.7 1 1 0 1 1 1 0 SNARE domain Tim17 PF02466.14 EIW65905.1 - 3.7e-24 85.2 0.0 5.8e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Init_tRNA_PT PF04179.7 EIW65906.1 - 6.2e-95 318.6 0.0 1.5e-94 317.4 0.0 1.6 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Myosin_head PF00063.16 EIW65911.1 - 8.2e-228 757.8 0.0 1.2e-227 757.2 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EIW65911.1 - 2.3e-40 138.0 0.0 5.2e-40 136.8 0.0 1.6 1 0 0 1 1 1 1 Myosin tail SH3_2 PF07653.12 EIW65911.1 - 1.9e-09 36.8 0.1 4.9e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW65911.1 - 2.2e-08 33.3 0.7 4.6e-08 32.3 0.5 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW65911.1 - 5.9e-08 32.1 0.0 5.9e-07 28.9 0.2 2.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 EIW65911.1 - 1.9e-05 24.7 0.9 4.6e-05 23.5 0.6 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 EIW65911.1 - 0.0044 17.1 0.0 0.018 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW65911.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IQ PF00612.22 EIW65911.1 - 0.013 15.1 12.4 0.13 11.9 0.4 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif AAA_17 PF13207.1 EIW65911.1 - 0.02 15.6 0.3 0.09 13.6 0.0 2.3 2 0 0 2 2 1 0 AAA domain Hpr_kinase_C PF07475.7 EIW65911.1 - 0.036 13.3 0.7 4.6 6.5 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_30 PF13604.1 EIW65911.1 - 0.057 12.9 0.2 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIW65911.1 - 0.06 13.1 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EIW65911.1 - 0.099 12.6 0.0 0.36 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EIW65911.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain CAF1 PF04857.15 EIW65912.1 - 4.6e-64 216.2 0.0 6.8e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RNase_H_2 PF13482.1 EIW65912.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 RNase_H superfamily Actin PF00022.14 EIW65915.1 - 1.8e-13 49.7 0.0 1.4e-12 46.8 0.0 2.0 2 1 0 2 2 2 1 Actin MRP-L28 PF09812.4 EIW65916.1 - 4.6e-05 23.2 0.5 0.00019 21.3 0.4 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 MAPEG PF01124.13 EIW65917.1 - 3e-13 49.5 3.7 4e-13 49.0 2.6 1.2 1 0 0 1 1 1 1 MAPEG family Zn_clus PF00172.13 EIW65919.1 - 5.6e-07 29.3 11.3 1.3e-06 28.2 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S18 PF01084.15 EIW65920.1 - 3.9e-11 42.6 0.1 5.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 PAP2 PF01569.16 EIW65921.1 - 4.8e-10 39.2 8.1 4.8e-10 39.2 5.6 1.9 2 2 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EIW65921.1 - 1.9e-06 27.5 5.5 1.9e-06 27.5 3.8 1.9 1 1 0 2 2 2 1 PAP2 superfamily Glyco_hydro_15 PF00723.16 EIW65922.1 - 1.7e-49 168.5 0.0 1.9e-47 161.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 IL10 PF00726.12 EIW65922.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Interleukin 10 AAA_11 PF13086.1 EIW65924.1 - 4.2e-57 193.4 0.0 6.6e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EIW65924.1 - 1.9e-54 184.0 0.0 3.3e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW65924.1 - 1.6e-10 40.5 0.0 1.9e-09 37.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EIW65924.1 - 8e-09 35.3 0.0 0.022 14.2 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EIW65924.1 - 2.6e-07 30.4 0.0 0.00054 19.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EIW65924.1 - 7.7e-05 22.1 0.0 0.00021 20.7 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EIW65924.1 - 0.0002 21.2 0.0 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW65924.1 - 0.0014 18.7 0.0 0.013 15.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW65924.1 - 0.0027 17.7 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.1 EIW65924.1 - 0.0048 17.0 0.0 0.082 13.0 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 EIW65924.1 - 0.006 16.0 0.0 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EIW65924.1 - 0.011 14.7 0.0 1.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EIW65924.1 - 0.036 13.3 0.0 0.59 9.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.24 EIW65924.1 - 0.11 12.6 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ricin_B_lectin PF00652.17 EIW65925.1 - 6.5e-11 42.3 4.1 5e-05 23.3 0.0 3.4 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIW65925.1 - 0.011 16.1 0.1 3 8.2 0.0 2.6 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIW65926.1 - 4e-09 36.5 9.5 0.001 19.0 3.2 3.1 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.17 EIW65927.1 - 3.8e-12 46.3 8.7 5.9e-05 23.0 0.2 4.1 2 1 1 4 4 4 4 Ricin-type beta-trefoil lectin domain PLDc_2 PF13091.1 EIW65928.1 - 2.4e-18 66.0 0.0 1.2e-10 41.2 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EIW65928.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phospholipase D Active site motif GFO_IDH_MocA PF01408.17 EIW65929.1 - 8.4e-21 74.7 0.0 1.8e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_S9 PF00326.16 EIW65930.1 - 4.7e-54 182.8 0.2 7.4e-54 182.1 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW65930.1 - 3.3e-09 36.6 0.0 7.7e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW65930.1 - 4.6e-05 23.3 0.1 0.00015 21.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EIW65930.1 - 0.0019 16.7 0.0 0.037 12.5 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EIW65930.1 - 0.0021 17.5 2.0 0.0038 16.6 1.4 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 EIW65930.1 - 0.0037 16.7 4.0 0.0088 15.4 1.2 2.3 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 EIW65930.1 - 0.019 14.5 0.0 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 EIW65930.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase UPF0227 PF05728.7 EIW65930.1 - 0.081 12.6 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) WD40 PF00400.27 EIW65930.1 - 0.35 10.8 0.1 0.35 10.8 0.1 3.3 4 0 0 4 4 4 0 WD domain, G-beta repeat PDEase_II PF02112.10 EIW65931.1 - 5.7e-30 104.3 0.0 2.2e-29 102.4 0.0 2.0 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EIW65931.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MCM2_N PF12619.3 EIW65932.1 - 1.9 8.4 5.9 1.4 8.8 3.2 1.4 1 1 0 1 1 1 0 Mini-chromosome maintenance protein 2 zf-CCHC PF00098.18 EIW65933.1 - 0.00065 19.5 2.2 0.00065 19.5 1.5 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 EIW65933.1 - 0.045 13.4 0.7 0.098 12.3 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIW65934.1 - 0.0029 17.4 2.2 0.0047 16.7 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW65934.1 - 0.019 14.6 1.0 0.054 13.1 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW65934.1 - 0.35 11.1 8.0 0.092 12.9 3.4 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW65934.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) SR-25 PF10500.4 EIW65935.1 - 0.0017 17.9 8.7 0.0017 17.9 6.0 2.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Nop14 PF04147.7 EIW65935.1 - 1.7 6.4 2.8 2.3 6.0 1.9 1.1 1 0 0 1 1 1 0 Nop14-like family SH3_8 PF13457.1 EIW65936.1 - 0.013 15.6 0.2 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 SH3-like domain Aminotran_5 PF00266.14 EIW65938.1 - 4.2e-32 111.2 0.0 5.6e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EIW65938.1 - 0.026 13.4 0.0 0.096 11.6 0.0 1.9 1 1 0 1 1 1 0 Aminotransferase class I and II B12-binding PF02310.14 EIW65938.1 - 0.046 13.5 0.1 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain COX16 PF14138.1 EIW65939.1 - 1.7e-22 79.3 2.6 8e-19 67.6 0.0 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein COX16 CCER1 PF15482.1 EIW65939.1 - 0.0056 16.3 0.3 0.0084 15.7 0.2 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing glutamate-rich protein family 1 GAGA_bind PF06217.7 EIW65939.1 - 0.064 13.2 1.4 0.083 12.8 1.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SR-25 PF10500.4 EIW65939.1 - 0.4 10.1 13.8 0.52 9.7 9.6 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Urm1 PF09138.6 EIW65940.1 - 2.5e-32 110.8 0.0 2.9e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EIW65940.1 - 4.1e-05 23.9 0.0 4.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 ThiS family BRK PF07533.11 EIW65940.1 - 0.051 13.0 0.1 0.088 12.2 0.1 1.3 1 0 0 1 1 1 0 BRK domain Mitofilin PF09731.4 EIW65941.1 - 1.6e-117 393.5 6.6 1.9e-117 393.3 4.6 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF883 PF05957.8 EIW65941.1 - 0.0019 18.5 2.2 0.0019 18.5 1.5 4.9 4 1 1 5 5 5 1 Bacterial protein of unknown function (DUF883) DUF1116 PF06545.6 EIW65941.1 - 0.043 12.9 0.1 0.087 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) ISG65-75 PF11727.3 EIW65941.1 - 7.8 5.4 18.8 3.2 6.7 4.8 2.4 2 0 0 2 2 2 0 Invariant surface glycoprotein ABC_tran PF00005.22 EIW65942.1 - 5.6e-47 159.4 0.0 4.4e-29 101.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW65942.1 - 5.5e-17 62.0 16.9 4.8e-10 39.3 0.9 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EIW65942.1 - 4.7e-09 35.7 0.6 0.005 16.0 1.1 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EIW65942.1 - 7.8e-07 29.0 0.0 0.039 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIW65942.1 - 2.1e-06 27.8 0.3 0.083 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EIW65942.1 - 4.5e-06 26.8 0.1 0.1 12.5 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EIW65942.1 - 6.5e-06 25.5 0.5 0.039 13.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EIW65942.1 - 1.5e-05 25.1 4.4 0.14 12.3 0.0 3.9 3 1 0 3 3 3 2 AAA domain T2SE PF00437.15 EIW65942.1 - 3.9e-05 22.6 0.3 0.062 12.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EIW65942.1 - 0.00036 19.9 3.0 0.54 9.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EIW65942.1 - 0.00045 19.7 0.5 0.56 9.5 0.0 3.1 4 0 0 4 4 3 2 AAA-like domain MMR_HSR1 PF01926.18 EIW65942.1 - 0.0011 18.9 0.2 0.31 11.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW65942.1 - 0.0016 17.6 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EIW65942.1 - 0.0016 17.9 0.0 1.6 8.1 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EIW65942.1 - 0.0017 17.5 0.1 0.79 8.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_23 PF13476.1 EIW65942.1 - 0.0032 17.8 0.2 1.1 9.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EIW65942.1 - 0.0051 17.2 0.1 1.8 9.0 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EIW65942.1 - 0.0056 16.5 0.1 2.1 8.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.1 EIW65942.1 - 0.0067 16.7 0.4 2.9 8.1 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIW65942.1 - 0.0084 16.9 0.8 0.44 11.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EIW65942.1 - 0.0085 15.5 3.9 0.41 10.0 0.4 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EIW65942.1 - 0.0098 15.5 2.4 1.1 8.9 0.2 3.4 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EIW65942.1 - 0.04 13.7 1.7 0.057 13.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_30 PF13604.1 EIW65942.1 - 0.044 13.3 0.7 1.4 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EIW65942.1 - 0.048 13.3 1.1 8 6.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Guanylate_kin PF00625.16 EIW65942.1 - 0.051 13.0 0.2 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase IstB_IS21 PF01695.12 EIW65942.1 - 0.052 12.9 0.3 6.8 6.0 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.24 EIW65942.1 - 0.056 13.6 1.0 5 7.3 0.1 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.10 EIW65942.1 - 0.079 11.5 0.0 0.42 9.2 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.17 EIW65942.1 - 0.2 11.8 0.8 11 6.3 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_14 PF13173.1 EIW65942.1 - 0.2 11.5 0.2 28 4.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EIW65942.1 - 0.59 9.9 6.9 0.24 11.1 1.0 2.6 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 EIW65943.1 - 2e-48 164.1 0.0 2.1e-28 99.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EIW65943.1 - 2.2e-28 99.4 19.0 5.9e-16 58.6 3.1 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EIW65943.1 - 2.7e-08 33.3 4.6 0.0028 16.9 2.0 4.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW65943.1 - 1.5e-07 31.6 1.1 0.12 12.3 0.4 4.3 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EIW65943.1 - 4.3e-06 26.8 0.2 0.09 12.7 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EIW65943.1 - 6.6e-06 25.6 1.1 0.062 12.6 0.1 3.0 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EIW65943.1 - 2.5e-05 23.6 0.7 0.13 11.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 EIW65943.1 - 3.2e-05 23.5 0.3 0.084 12.2 0.0 3.0 3 1 0 3 3 3 2 AAA-like domain AAA_33 PF13671.1 EIW65943.1 - 3.7e-05 23.6 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EIW65943.1 - 4.8e-05 23.7 0.0 0.019 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIW65943.1 - 5.4e-05 23.3 0.8 0.081 13.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EIW65943.1 - 0.00046 19.8 0.5 0.062 12.9 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EIW65943.1 - 0.00047 19.1 0.1 0.97 8.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.1 EIW65943.1 - 0.00053 20.2 0.0 1 9.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 EIW65943.1 - 0.0028 17.0 2.6 0.11 11.9 0.5 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EIW65943.1 - 0.0046 16.4 0.0 2.4 7.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 EIW65943.1 - 0.0061 16.2 0.2 0.72 9.5 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EIW65943.1 - 0.0063 15.6 0.1 0.4 9.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.24 EIW65943.1 - 0.009 16.2 2.2 0.62 10.2 0.1 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EIW65943.1 - 0.013 15.3 1.3 0.02 14.7 0.1 1.9 2 0 0 2 2 1 0 Domain of unknown function DUF87 Miro PF08477.8 EIW65943.1 - 0.025 15.0 0.0 14 6.1 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Pox_A32 PF04665.7 EIW65943.1 - 0.025 13.8 0.3 0.82 8.9 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_14 PF13173.1 EIW65943.1 - 0.026 14.3 0.5 17 5.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 EIW65943.1 - 0.028 13.6 0.0 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EIW65943.1 - 0.034 14.1 0.1 2.6 8.0 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 EIW65943.1 - 0.038 12.6 1.2 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 EIW65943.1 - 0.066 12.8 0.2 0.49 10.0 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EIW65943.1 - 0.099 12.2 2.9 7.9 6.1 0.0 2.9 3 0 0 3 3 2 0 NACHT domain AAA_17 PF13207.1 EIW65943.1 - 0.11 13.2 5.0 6.3 7.6 2.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EIW65943.1 - 0.27 11.0 1.9 4.4 7.1 0.1 3.1 3 0 0 3 3 2 0 Part of AAA domain DUF2075 PF09848.4 EIW65943.1 - 0.43 9.4 0.1 9.2 5.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Macoilin PF09726.4 EIW65944.1 - 0.24 9.6 21.6 0.34 9.1 15.0 1.3 1 0 0 1 1 1 0 Transmembrane protein zf-CCHC PF00098.18 EIW65945.1 - 0.0025 17.6 1.9 0.0046 16.8 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW65945.1 - 0.063 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Zip PF02535.17 EIW65946.1 - 9.9e-54 182.4 8.6 1.1e-53 182.2 6.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4140 PF13600.1 EIW65947.1 - 0.42 11.0 3.8 0.33 11.4 0.3 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3682 PF12446.3 EIW65948.1 - 0.096 12.9 5.1 0.13 12.5 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) PBP1_TM PF14812.1 EIW65948.1 - 4.9 7.5 10.7 11 6.4 7.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC_tran PF00005.22 EIW65949.1 - 1.5e-45 154.8 0.0 2.7e-22 79.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW65949.1 - 1.4e-15 58.0 7.2 4.1e-05 23.6 0.1 4.3 3 1 1 4 4 4 3 AAA domain AAA_29 PF13555.1 EIW65949.1 - 9.1e-09 34.7 0.6 0.0018 17.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EIW65949.1 - 1e-08 34.6 1.4 0.12 11.5 0.0 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIW65949.1 - 8.2e-08 32.4 1.2 0.024 14.6 0.0 3.3 3 2 1 4 4 3 2 AAA ATPase domain AAA_15 PF13175.1 EIW65949.1 - 2e-07 30.3 2.6 0.061 12.3 0.0 3.7 3 1 0 4 4 4 3 AAA ATPase domain AAA_23 PF13476.1 EIW65949.1 - 2.5e-07 31.2 4.4 0.0025 18.1 0.0 3.5 4 1 0 4 4 3 2 AAA domain Miro PF08477.8 EIW65949.1 - 4.7e-07 30.3 0.0 0.017 15.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EIW65949.1 - 4.9e-07 29.9 0.6 0.0066 16.5 0.0 3.3 4 1 0 4 4 2 2 AAA domain ABC_tran_2 PF12848.2 EIW65949.1 - 5.5e-07 29.3 0.1 5.5e-07 29.3 0.1 2.8 4 0 0 4 4 2 1 ABC transporter AAA_17 PF13207.1 EIW65949.1 - 1.7e-06 28.8 0.8 0.024 15.4 0.0 3.4 3 1 0 4 4 2 2 AAA domain DUF258 PF03193.11 EIW65949.1 - 2.5e-06 26.7 0.0 0.0013 17.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIW65949.1 - 5.4e-06 26.3 0.2 0.024 14.4 0.2 3.0 2 1 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.18 EIW65949.1 - 5.4e-06 26.3 0.8 0.011 15.6 0.3 3.1 3 1 0 3 3 2 2 50S ribosome-binding GTPase NACHT PF05729.7 EIW65949.1 - 7e-06 25.7 0.0 0.073 12.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.1 EIW65949.1 - 1.1e-05 24.8 0.0 0.75 9.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EIW65949.1 - 3.4e-05 24.1 1.6 0.32 11.2 0.0 3.2 3 1 0 4 4 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EIW65949.1 - 6.3e-05 22.5 0.0 0.22 10.9 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 EIW65949.1 - 8.4e-05 22.1 0.0 0.35 10.2 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain MobB PF03205.9 EIW65949.1 - 0.00057 19.6 0.4 0.37 10.5 0.0 3.0 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EIW65949.1 - 0.00069 19.7 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase KAP_NTPase PF07693.9 EIW65949.1 - 0.00077 18.5 0.0 0.56 9.1 0.0 2.4 2 1 0 2 2 2 2 KAP family P-loop domain AAA_28 PF13521.1 EIW65949.1 - 0.0019 18.1 0.0 1.6 8.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain Pox_A32 PF04665.7 EIW65949.1 - 0.0023 17.2 0.1 2.1 7.5 0.0 3.0 2 1 1 3 3 3 1 Poxvirus A32 protein DUF87 PF01935.12 EIW65949.1 - 0.0027 17.5 3.4 1.5 8.5 0.0 3.7 4 1 1 5 5 3 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 EIW65949.1 - 0.0051 16.6 0.1 1.1 9.1 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EIW65949.1 - 0.0051 16.3 0.3 1.7 8.0 0.0 2.9 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.13 EIW65949.1 - 0.0072 15.3 0.8 1.9 7.4 0.0 2.6 3 0 0 3 3 2 1 Septin AAA_33 PF13671.1 EIW65949.1 - 0.01 15.7 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EIW65949.1 - 0.02 13.4 0.0 1.8 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EIW65949.1 - 0.022 14.4 0.2 9.7 5.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EIW65949.1 - 0.024 14.8 0.3 8 6.6 0.1 3.6 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EIW65949.1 - 0.024 14.2 0.0 2.1 7.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EIW65949.1 - 0.025 13.8 0.0 0.43 9.8 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.10 EIW65949.1 - 0.039 13.6 0.3 4.8 6.8 0.1 3.0 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.4 EIW65949.1 - 0.04 13.3 0.0 7.2 6.0 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DAP3 PF10236.4 EIW65949.1 - 0.047 12.6 0.1 6 5.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 EIW65949.1 - 0.047 12.5 0.0 1.6 7.5 0.0 2.4 2 1 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 EIW65949.1 - 0.055 12.2 0.7 6.1 5.5 0.0 2.9 3 0 0 3 3 3 0 ArgK protein AAA_14 PF13173.1 EIW65949.1 - 0.06 13.2 0.0 23 4.8 0.0 3.7 4 0 0 4 4 2 0 AAA domain DUF2813 PF11398.3 EIW65949.1 - 0.074 12.1 0.1 8.1 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) DUF2250 PF10007.4 EIW65949.1 - 0.098 12.5 0.7 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) NPDC1 PF06809.6 EIW65949.1 - 0.22 10.2 0.4 0.32 9.7 0.2 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) DUF2052 PF09747.4 EIW65950.1 - 3.5e-06 27.0 8.5 3.5e-06 27.0 5.9 1.9 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Fasciclin PF02469.17 EIW65951.1 - 1.2e-05 25.2 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain CPSase_sm_chain PF00988.17 EIW65952.1 - 5.1e-44 148.9 0.0 8.6e-44 148.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EIW65952.1 - 9.1e-36 123.1 0.0 1.3e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIW65952.1 - 3.9e-07 29.7 0.0 3.5e-06 26.6 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EIW65952.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family zf-CCHC PF00098.18 EIW65953.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW65953.1 - 0.27 11.5 9.2 0.069 13.3 4.2 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW65953.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Amidase PF01425.16 EIW65955.1 - 5.1e-84 282.6 0.0 6.5e-84 282.3 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EIW65956.1 - 4.2e-46 157.2 28.8 6.6e-45 153.3 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW65956.1 - 2.6e-12 46.0 11.0 2.6e-12 46.0 7.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EIW65956.1 - 4e-06 25.1 1.0 9.2e-06 23.9 0.7 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.8 EIW65956.1 - 3.2e-05 22.3 5.0 6.2e-05 21.3 3.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EIW65956.1 - 0.2 9.7 13.7 0.0032 15.6 3.8 2.0 3 0 0 3 3 3 0 Transmembrane secretion effector MFS_2 PF13347.1 EIW65956.1 - 6.6 5.0 21.0 0.012 13.9 3.0 3.3 3 1 1 4 4 4 0 MFS/sugar transport protein zf-C3HC4_2 PF13923.1 EIW65957.1 - 8.6e-09 35.2 11.9 1.6e-08 34.4 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW65957.1 - 3.5e-08 32.9 6.4 6e-08 32.2 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW65957.1 - 5.2e-08 32.4 9.9 9.3e-08 31.6 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW65957.1 - 1.2e-06 28.1 8.8 2.4e-06 27.2 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EIW65957.1 - 7.3e-06 25.6 7.6 1.3e-05 24.8 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIW65957.1 - 1.1e-05 25.1 8.0 4.6e-05 23.2 6.0 1.7 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIW65957.1 - 0.0042 16.7 6.3 0.0042 16.7 4.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EIW65957.1 - 0.042 13.3 7.5 0.086 12.3 5.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 EIW65957.1 - 0.11 12.6 4.4 0.28 11.3 3.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 EIW65957.1 - 0.16 11.4 7.7 0.47 9.9 5.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PARP PF00644.15 EIW65961.1 - 1.6e-11 43.9 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EIW65961.1 - 4.9e-07 29.2 0.0 1.3e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-U1 PF06220.7 EIW65962.1 - 1.4e-19 69.3 5.1 2.2e-19 68.6 3.5 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EIW65962.1 - 0.021 14.9 5.2 0.021 14.9 3.6 1.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PseudoU_synth_1 PF01416.15 EIW65963.1 - 3.9e-30 104.3 0.0 4.1e-18 65.7 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase Prefoldin_2 PF01920.15 EIW65963.1 - 0.052 13.3 4.1 11 5.8 0.4 3.0 3 0 0 3 3 3 0 Prefoldin subunit Peptidase_M28 PF04389.12 EIW65964.1 - 2.7e-27 95.6 0.1 4.7e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIW65964.1 - 0.00027 20.5 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Mur_ligase_M PF08245.7 EIW65965.1 - 3.6e-05 23.8 0.3 0.0014 18.7 0.1 2.9 1 1 1 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EIW65965.1 - 0.0035 17.3 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain UCH PF00443.24 EIW65966.1 - 2.9e-37 128.2 0.5 4.9e-37 127.5 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW65966.1 - 2.4e-17 63.3 0.2 4.8e-17 62.3 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EIW65966.1 - 0.00025 21.3 0.2 2.8 8.3 0.2 4.0 2 1 0 2 2 2 1 DUSP domain Stonin2_N PF12016.3 EIW65966.1 - 0.015 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Stonin 2 Gaa1 PF04114.9 EIW65967.1 - 4.2e-51 174.2 1.5 1.4e-50 172.4 0.0 2.2 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component FAD_binding_1 PF00667.15 EIW65968.1 - 0.03 13.7 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DUF2358 PF10184.4 EIW65968.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) Geminin PF07412.7 EIW65970.1 - 0.091 12.4 0.4 0.12 12.0 0.3 1.1 1 0 0 1 1 1 0 Geminin ICL PF00463.16 EIW65971.1 - 0.24 9.5 0.2 2 6.5 0.0 1.9 2 0 0 2 2 2 0 Isocitrate lyase family zf-AN1 PF01428.11 EIW65972.1 - 0.46 10.4 9.4 0.96 9.3 6.5 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger UBX PF00789.15 EIW65973.1 - 1.7e-11 44.0 0.2 3.5e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 EIW65973.1 - 0.0038 17.0 1.2 0.034 14.0 0.0 2.9 3 0 0 3 3 3 1 UBA/TS-N domain zf-C2H2_2 PF12756.2 EIW65973.1 - 0.019 15.0 0.1 0.044 13.9 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_5 PF13719.1 EIW65973.1 - 0.14 11.7 0.3 0.34 10.5 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIW65973.1 - 0.15 11.8 0.4 0.38 10.4 0.3 1.8 1 0 0 1 1 1 0 zinc-ribbon domain SOBP PF15279.1 EIW65973.1 - 0.82 9.9 5.6 1 9.6 3.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PTH2 PF01981.11 EIW65974.1 - 0.00048 19.7 0.0 0.00068 19.3 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 RXT2_N PF08595.6 EIW65975.1 - 0.11 12.2 0.0 0.11 12.2 0.0 3.0 2 2 2 4 4 4 0 RXT2-like, N-terminal PRCH PF03967.8 EIW65975.1 - 0.12 11.9 1.1 2 7.9 0.2 2.5 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region TFIIA PF03153.8 EIW65975.1 - 2.8 7.7 39.1 30 4.3 27.1 1.9 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 EIW65975.1 - 8.2 4.4 47.7 10 4.1 33.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3376 PF11856.3 EIW65976.1 - 0.041 13.2 5.2 0.042 13.2 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) TPR_MLP1_2 PF07926.7 EIW65976.1 - 0.1 12.3 15.2 0.13 11.9 10.5 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2043 PF09740.4 EIW65976.1 - 0.15 12.1 3.5 0.37 10.9 1.1 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2043) DSX_dimer PF08828.5 EIW65976.1 - 0.35 10.4 2.9 0.72 9.4 0.6 2.2 1 1 1 2 2 2 0 Doublesex dimerisation domain OEP PF02321.13 EIW65976.1 - 0.99 8.9 12.2 1.2 8.6 8.5 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DBINO PF13892.1 EIW65976.1 - 1 9.3 15.0 1.4 8.9 10.4 1.2 1 0 0 1 1 1 0 DNA-binding domain DUF2570 PF10828.3 EIW65976.1 - 1.4 8.5 8.3 2.1 7.9 5.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) FlxA PF14282.1 EIW65976.1 - 1.5 8.8 9.6 2.2 8.2 6.6 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF3523 PF12037.3 EIW65976.1 - 1.5 7.6 17.3 1.7 7.5 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) NAM-associated PF14303.1 EIW65976.1 - 3.8 7.8 12.3 5.7 7.2 8.5 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CAF-1_p150 PF11600.3 EIW65976.1 - 3.9 6.8 18.8 4.9 6.4 13.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.6 EIW65976.1 - 9.4 4.3 13.8 10 4.2 9.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NPR2 PF06218.6 EIW65977.1 - 2.1e-92 310.0 0.0 2.5e-77 260.4 0.0 2.4 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Corona_nucleoca PF00937.13 EIW65977.1 - 0.033 13.1 6.3 0.051 12.5 4.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DALR_2 PF09190.6 EIW65978.1 - 0.059 13.6 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 DALR domain DUF2760 PF10816.3 EIW65978.1 - 0.089 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) Gag_p24 PF00607.15 EIW65979.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) ECH PF00378.15 EIW65980.1 - 6.8e-70 234.9 0.3 8.4e-70 234.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family EIF_2_alpha PF07541.7 EIW65981.1 - 1.3e-41 140.8 0.0 3.8e-41 139.3 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EIW65981.1 - 1.9e-11 43.8 1.8 3.3e-11 43.1 0.4 2.0 2 0 0 2 2 2 1 S1 RNA binding domain SUI1 PF01253.17 EIW65985.1 - 2e-14 53.1 0.3 5.5e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Translation initiation factor SUI1 SWIB PF02201.13 EIW65985.1 - 0.00021 20.9 0.0 0.00062 19.3 0.0 1.7 1 1 1 2 2 2 1 SWIB/MDM2 domain Kin17_mid PF10357.4 EIW65985.1 - 0.019 14.6 0.1 0.034 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein DUF1129 PF06570.6 EIW65986.1 - 0.47 9.7 2.1 0.72 9.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Reprolysin_5 PF13688.1 EIW65987.1 - 2.4e-42 145.0 2.6 2.4e-42 145.0 1.8 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EIW65987.1 - 3e-36 125.0 0.8 3e-36 125.0 0.6 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EIW65987.1 - 3.8e-36 124.5 0.2 3.8e-36 124.5 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EIW65987.1 - 4.7e-18 65.8 0.0 4.7e-18 65.8 0.0 3.0 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EIW65987.1 - 1.4e-16 60.4 24.7 1.4e-16 60.4 17.1 4.2 3 1 1 4 4 4 1 Disintegrin Reprolysin PF01421.14 EIW65987.1 - 0.00021 20.9 3.1 0.00021 20.9 2.2 2.0 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease S1FA PF04689.8 EIW65987.1 - 0.31 10.9 0.0 16 5.4 0.0 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA UPF0061 PF02696.9 EIW65988.1 - 2.8e-85 286.4 0.0 4.4e-80 269.3 0.0 2.3 1 1 1 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family Retrotrans_gag PF03732.12 EIW65991.1 - 5.9e-09 35.8 0.2 1.6e-08 34.4 0.2 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIW65991.1 - 0.0021 17.9 1.9 0.0046 16.8 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF1598 PF07643.6 EIW65991.1 - 0.036 14.1 1.4 0.046 13.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) TraC_F_IV PF11130.3 EIW65991.1 - 0.073 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer DDE_3 PF13358.1 EIW65992.1 - 2.2e-08 33.9 0.3 3.3e-08 33.4 0.2 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3069 PF11269.3 EIW65992.1 - 0.085 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) Post_transc_reg PF13797.1 EIW65992.1 - 0.11 12.1 0.4 0.15 11.7 0.3 1.2 1 0 0 1 1 1 0 Post-transcriptional regulator DUF1044 PF06296.7 EIW65993.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1044) AflR PF08493.5 EIW65994.1 - 0.063 12.3 0.2 0.071 12.1 0.1 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein Ribosomal_L1 PF00687.16 EIW65996.1 - 0.03 13.6 0.0 6.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L1p/L10e family LUC7 PF03194.10 EIW65997.1 - 3.1e-63 213.6 3.1 3.1e-63 213.6 2.2 2.1 3 0 0 3 3 3 1 LUC7 N_terminus POP1 PF06978.6 EIW65998.1 - 1.3e-47 161.8 12.6 2e-25 89.5 0.1 2.4 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EIW65998.1 - 2e-21 75.6 0.4 4.2e-21 74.5 0.3 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.16 EIW65998.1 - 0.0012 18.2 0.0 0.0058 16.0 0.0 2.0 3 0 0 3 3 3 1 Aminomethyltransferase folate-binding domain Tom37_C PF11801.3 EIW65999.1 - 3.6e-07 30.1 0.0 6.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain HEAT_2 PF13646.1 EIW66001.1 - 7.4e-31 106.2 0.1 4.1e-11 43.0 0.0 3.4 1 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EIW66001.1 - 5.5e-18 63.5 0.0 0.013 15.9 0.0 5.7 5 0 0 5 5 5 5 PBS lyase HEAT-like repeat HEAT PF02985.17 EIW66001.1 - 6.7e-11 41.3 0.0 0.024 14.7 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EIW66001.1 - 3.7e-07 30.4 0.3 0.14 12.6 0.0 4.1 2 2 3 5 5 5 3 HEAT-like repeat PFU PF09070.6 EIW66002.1 - 2.8e-43 146.6 1.1 4.7e-43 145.8 0.2 1.8 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EIW66002.1 - 3.6e-39 134.1 0.0 5.3e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 EIW66002.1 - 2.7e-31 106.3 15.4 6.4e-06 25.8 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Abhydrolase_3 PF07859.8 EIW66003.1 - 1.7e-40 138.8 0.0 5.1e-32 111.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW66003.1 - 3.2e-11 42.4 0.0 1.4e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIW66003.1 - 0.00028 20.6 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EIW66003.1 - 0.011 14.4 0.3 2 7.0 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_S9 PF00326.16 EIW66003.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family NatB_MDM20 PF09797.4 EIW66004.1 - 2.6e-33 115.2 0.0 6.4e-33 113.9 0.0 1.6 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_17 PF13431.1 EIW66004.1 - 0.067 13.4 0.0 0.37 11.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CTK3 PF12243.3 EIW66005.1 - 2e-43 147.3 0.0 2.9e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EIW66005.1 - 1.1e-16 60.6 8.5 1.1e-16 60.6 5.9 2.1 2 1 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus zf-C3HC PF07967.8 EIW66006.1 - 2e-16 59.9 0.0 2e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.5 EIW66006.1 - 8e-13 48.0 2.3 8e-11 41.6 0.0 2.8 2 1 1 3 3 3 2 Rsm1-like BIR PF00653.16 EIW66006.1 - 0.004 17.5 0.0 0.39 11.1 0.0 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain RabGAP-TBC PF00566.13 EIW66007.1 - 7.9e-30 103.9 0.0 1.1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CorA PF01544.13 EIW66008.1 - 1.4e-24 86.6 0.0 5.7e-10 38.6 0.0 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein zf-AN1 PF01428.11 EIW66009.1 - 0.0047 16.7 3.1 0.0047 16.7 2.2 1.8 2 0 0 2 2 2 1 AN1-like Zinc finger APH PF01636.18 EIW66009.1 - 0.0077 15.9 0.6 0.0077 15.9 0.4 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family ResIII PF04851.10 EIW66010.1 - 2.2e-17 63.4 0.0 4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIW66010.1 - 5.7e-15 55.2 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW66010.1 - 4e-11 42.6 0.0 8.1e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIW66010.1 - 0.0016 17.3 0.0 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_30 PF13604.1 EIW66010.1 - 0.0041 16.7 0.3 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIW66010.1 - 0.01 15.9 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EIW66010.1 - 0.017 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EIW66010.1 - 0.045 13.3 0.3 1.7 8.1 0.0 2.7 1 1 1 2 2 2 0 AAA domain TrkA_N PF02254.13 EIW66010.1 - 0.071 13.1 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain AAA_24 PF13479.1 EIW66010.1 - 0.14 11.7 0.2 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain UDPGP PF01704.13 EIW66011.1 - 1.4e-48 165.4 0.0 1.8e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EIW66011.1 - 0.0023 18.0 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fig1 PF12351.3 EIW66012.1 - 1 9.1 5.6 2.6 7.9 3.9 1.6 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 tRNA_bind PF01588.15 EIW66013.1 - 9.6e-28 95.8 0.1 2.1e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain Gly-zipper_OmpA PF13436.1 EIW66013.1 - 0.022 14.4 3.5 0.042 13.5 2.5 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Perilipin PF03036.11 EIW66013.1 - 0.054 12.3 2.3 0.094 11.5 1.6 1.3 1 0 0 1 1 1 0 Perilipin family GTP_EFTU PF00009.22 EIW66014.1 - 8.7e-44 149.2 0.8 1.1e-43 148.9 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIW66014.1 - 4.4e-22 78.0 0.0 1.3e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIW66014.1 - 2.7e-09 37.0 0.1 8.1e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW66014.1 - 0.0026 17.7 0.0 0.0066 16.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase F-box-like PF12937.2 EIW66016.1 - 0.079 12.6 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 F-box-like Rcd1 PF04078.8 EIW66017.1 - 1.8e-127 423.6 0.2 2.1e-127 423.4 0.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like FAM60A PF15396.1 EIW66018.1 - 0.15 11.8 0.5 0.15 11.7 0.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A HEAT_EZ PF13513.1 EIW66019.1 - 1.2e-26 92.4 8.0 5.1e-08 33.1 0.0 13.5 12 4 4 16 16 16 3 HEAT-like repeat HEAT_2 PF13646.1 EIW66019.1 - 4.1e-24 84.6 2.3 6.4e-05 23.1 0.4 9.0 4 2 5 9 9 9 6 HEAT repeats HEAT PF02985.17 EIW66019.1 - 2.3e-21 73.8 10.3 0.00041 20.1 0.0 12.0 13 0 0 13 13 12 4 HEAT repeat IBN_N PF03810.14 EIW66019.1 - 3.6e-09 36.4 0.7 2.2e-06 27.5 0.3 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EIW66019.1 - 5e-09 36.4 0.0 2.6 8.4 0.0 7.4 8 1 1 9 9 9 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EIW66019.1 - 8e-08 31.0 0.1 0.14 10.4 0.0 4.6 3 2 1 4 4 4 3 Adaptin N terminal region Cnd1 PF12717.2 EIW66019.1 - 1.6e-06 28.0 0.4 0.98 9.2 0.0 5.0 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EIW66019.1 - 5e-06 26.3 0.2 3.3 7.7 0.0 4.9 6 0 0 6 6 6 2 HEAT repeat associated with sister chromatid cohesion Ipi1_N PF12333.3 EIW66019.1 - 0.00011 22.1 0.0 26 4.8 0.0 6.0 3 1 1 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Xpo1 PF08389.7 EIW66019.1 - 0.0003 20.7 1.5 5 7.0 0.3 5.0 3 2 1 4 4 4 2 Exportin 1-like protein Sec7_N PF12783.2 EIW66019.1 - 0.09 12.2 0.0 0.6 9.5 0.0 2.5 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UDG PF03167.14 EIW66020.1 - 1.6e-15 56.8 0.0 4.6e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily CPSF_A PF03178.10 EIW66021.1 - 5.8e-78 262.2 0.0 3.6e-77 259.5 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EIW66021.1 - 5.9e-11 41.1 0.0 1.6e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Cytochrom_C1 PF02167.10 EIW66022.1 - 1.5e-84 283.0 0.0 1.8e-84 282.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EIW66022.1 - 0.00038 20.5 0.0 0.00077 19.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EIW66022.1 - 0.0093 16.7 0.2 0.029 15.1 0.1 1.9 1 1 1 2 2 2 1 Cytochrome c CDC45 PF02724.9 EIW66024.1 - 2.3 6.1 37.2 1.2 7.1 4.6 2.3 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 EIW66024.1 - 8.9 4.0 40.6 3.1 5.5 4.4 2.4 2 0 0 2 2 2 0 Nop14-like family CPSase_L_D2 PF02786.12 EIW66026.1 - 2e-80 269.0 0.1 3.3e-80 268.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EIW66026.1 - 7.4e-68 227.8 0.0 1.2e-67 227.1 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EIW66026.1 - 1.7e-36 124.6 0.1 4.4e-36 123.3 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIW66026.1 - 6e-30 103.3 0.0 1.8e-29 101.8 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EIW66026.1 - 2.7e-28 99.2 0.0 4.5e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EIW66026.1 - 1.1e-18 67.6 0.1 2.1e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EIW66026.1 - 3.6e-17 61.7 6.2 6.9e-17 60.8 3.3 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EIW66026.1 - 1.3e-16 60.2 0.1 3.6e-11 42.3 0.0 2.5 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EIW66026.1 - 6.4e-15 54.5 3.4 3.3e-07 29.8 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 EIW66026.1 - 3.2e-10 39.8 1.8 0.00055 19.3 0.0 2.6 2 0 0 2 2 2 2 HlyD family secretion protein Dala_Dala_lig_C PF07478.8 EIW66026.1 - 6.8e-10 38.6 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EIW66026.1 - 1.3e-07 31.1 0.0 3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EIW66026.1 - 3.2e-06 26.7 0.0 0.0023 17.4 0.0 2.8 3 0 0 3 3 2 2 RimK-like ATP-grasp domain HlyD_3 PF13437.1 EIW66026.1 - 6.5e-06 26.4 1.3 0.27 11.5 0.0 3.6 4 0 0 4 4 4 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 EIW66026.1 - 0.00016 21.5 0.0 0.00042 20.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EIW66026.1 - 0.0012 18.0 1.1 0.67 9.0 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein NQRA PF05896.6 EIW66026.1 - 0.0027 16.9 0.2 0.0056 15.9 0.2 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.14 EIW66026.1 - 0.0045 16.6 1.4 0.019 14.6 0.5 2.4 2 1 1 3 3 2 1 Glycine cleavage H-protein GARS_A PF01071.14 EIW66026.1 - 0.0099 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.1 EIW66026.1 - 0.013 15.2 1.0 0.042 13.5 0.7 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain BSP_II PF05432.6 EIW66029.1 - 0.0023 17.2 7.7 0.0043 16.3 5.4 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 EIW66029.1 - 0.0041 16.3 0.9 0.0041 16.3 0.6 1.4 2 0 0 2 2 2 1 Myc amino-terminal region Nucleoplasmin PF03066.10 EIW66029.1 - 0.0055 16.2 0.2 0.0066 15.9 0.1 1.2 1 0 0 1 1 1 1 Nucleoplasmin VIT1 PF01988.14 EIW66029.1 - 0.013 15.0 5.1 0.017 14.5 3.5 1.1 1 0 0 1 1 1 0 VIT family PBP1_TM PF14812.1 EIW66029.1 - 0.056 13.7 1.1 0.056 13.7 0.8 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 EIW66029.1 - 0.2 11.9 3.1 0.34 11.1 2.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VID27 PF08553.5 EIW66029.1 - 0.91 7.6 4.0 1.1 7.3 2.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein zf-CCHC PF00098.18 EIW66030.1 - 0.001 18.9 1.5 0.0016 18.2 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66030.1 - 0.81 9.9 7.9 0.14 12.4 2.6 1.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66030.1 - 1.2 7.6 2.8 1.6 7.2 1.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) RPAP1_C PF08620.5 EIW66031.1 - 3.7e-21 74.7 0.0 1.4e-20 72.8 0.0 2.0 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EIW66031.1 - 5e-08 32.4 4.6 5e-08 32.4 3.2 3.0 3 0 0 3 3 3 1 RPAP1-like, N-terminal SR-25 PF10500.4 EIW66031.1 - 0.00013 21.5 8.8 0.00013 21.5 6.1 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF3782 PF12644.2 EIW66031.1 - 6.3 6.6 12.3 1.1 9.1 4.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) MIF4G PF02854.14 EIW66032.1 - 3.7e-46 157.1 0.4 6.4e-31 107.4 0.1 2.6 2 0 0 2 2 2 2 MIF4G domain Upf2 PF04050.9 EIW66032.1 - 3.9e-21 75.5 2.5 3.9e-21 75.5 1.7 2.3 2 0 0 2 2 2 1 Up-frameshift suppressor 2 WD40 PF00400.27 EIW66033.1 - 2.1e-15 55.9 8.8 7.3e-06 25.6 0.2 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat MCM PF00493.18 EIW66034.1 - 2e-137 457.4 0.0 1.2e-136 454.8 0.0 1.9 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EIW66034.1 - 4.9e-28 98.0 1.3 2e-27 96.0 0.0 2.6 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIW66034.1 - 1.1e-07 31.2 0.0 1.1e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIW66034.1 - 3.4e-07 30.0 0.1 3e-06 27.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EIW66034.1 - 0.026 14.9 0.3 0.093 13.1 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EIW66034.1 - 0.046 13.1 0.1 0.51 9.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DASH_Hsk3 PF08227.6 EIW66035.1 - 9.6e-14 51.3 3.8 1.5e-13 50.7 2.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like UPF0449 PF15136.1 EIW66035.1 - 0.01 15.9 0.1 0.016 15.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Sec2p PF06428.6 EIW66035.1 - 0.11 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p FAR1 PF03101.10 EIW66036.1 - 0.0047 17.4 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain MCM_N PF14551.1 EIW66037.1 - 0.00073 20.0 0.0 0.001 19.5 0.0 1.2 1 0 0 1 1 1 1 MCM N-terminal domain Sigma70_ner PF04546.8 EIW66037.1 - 0.0022 17.6 2.7 0.0027 17.3 1.9 1.0 1 0 0 1 1 1 1 Sigma-70, non-essential region PKI PF02827.11 EIW66037.1 - 0.012 15.7 0.6 0.018 15.1 0.3 1.4 1 1 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF3073 PF11273.3 EIW66037.1 - 0.12 12.9 0.8 0.12 12.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) tRNA-synt_2b PF00587.20 EIW66040.1 - 5.7e-64 214.8 0.2 8.9e-64 214.2 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIW66040.1 - 1.9e-17 62.9 0.4 5.3e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain SpoIISA_toxin PF14171.1 EIW66040.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Cyclin_N PF00134.18 EIW66041.1 - 3.3e-10 39.6 0.0 1.7e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIW66041.1 - 0.0028 17.5 0.3 0.16 11.8 0.0 2.9 2 2 1 3 3 3 1 Cyclin, C-terminal domain UTP15_C PF09384.5 EIW66041.1 - 0.054 13.1 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 UTP15 C terminal Clat_adaptor_s PF01217.15 EIW66042.1 - 5.6e-46 155.7 0.0 1.4e-32 112.3 0.1 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain adh_short PF00106.20 EIW66043.1 - 6.7e-09 35.8 1.3 1.3e-06 28.4 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EIW66043.1 - 0.041 13.5 0.1 0.078 12.6 0.1 1.5 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 EIW66043.1 - 0.15 12.0 0.3 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding UQ_con PF00179.21 EIW66044.1 - 6.9e-18 64.4 0.0 7e-18 64.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIW66044.1 - 0.053 13.4 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain Dynein_heavy PF03028.10 EIW66046.1 - 2.8e-172 574.3 0.0 5.5e-172 573.4 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EIW66046.1 - 4.7e-132 440.3 10.8 5.2e-131 436.9 1.9 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EIW66046.1 - 7.9e-81 270.9 0.0 7.7e-80 267.7 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EIW66046.1 - 9.5e-45 152.1 0.2 3.3e-44 150.4 0.0 2.0 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EIW66046.1 - 6.5e-44 149.9 0.1 9.1e-43 146.1 0.1 2.4 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EIW66046.1 - 4.4e-42 144.0 8.3 7e-42 143.4 5.8 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EIW66046.1 - 7.4e-28 97.0 0.0 5.9e-12 45.4 0.0 6.8 7 1 0 7 7 6 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EIW66046.1 - 1e-20 74.0 0.0 2.9e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EIW66046.1 - 1.6e-13 50.9 0.0 0.022 14.8 0.0 6.1 5 0 0 5 5 5 3 AAA domain AAA PF00004.24 EIW66046.1 - 3.8e-13 49.7 0.3 0.0048 17.0 0.0 5.2 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIW66046.1 - 2.9e-08 33.6 0.1 0.55 10.0 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.1 EIW66046.1 - 1.5e-06 27.8 0.4 0.66 9.7 0.0 4.9 4 0 0 4 4 4 2 Part of AAA domain AAA_18 PF13238.1 EIW66046.1 - 3.6e-06 27.3 1.0 0.51 10.6 0.0 5.1 5 0 0 5 5 4 1 AAA domain AAA_17 PF13207.1 EIW66046.1 - 4.1e-06 27.6 0.0 2.6 8.8 0.0 5.2 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.16 EIW66046.1 - 2.6e-05 23.4 0.4 0.51 9.4 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIW66046.1 - 3.8e-05 23.5 0.0 0.36 10.7 0.0 4.7 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 EIW66046.1 - 5.2e-05 22.2 0.0 0.02 13.8 0.0 3.4 3 0 0 3 3 3 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 EIW66046.1 - 0.00012 21.5 1.4 0.16 11.3 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein Phlebovirus_NSM PF07246.6 EIW66046.1 - 0.00093 18.4 0.3 0.0026 16.9 0.2 1.7 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M RNA_helicase PF00910.17 EIW66046.1 - 0.0086 16.2 0.0 13 6.0 0.0 4.2 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.1 EIW66046.1 - 0.02 14.3 1.6 0.75 9.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.1 EIW66046.1 - 0.023 14.2 0.0 14 5.2 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain ERM PF00769.14 EIW66046.1 - 0.33 10.4 21.6 1.3 8.5 5.8 2.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 EIW66046.1 - 1.6 7.8 6.6 0.73 8.9 1.2 2.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EIW66046.1 - 9.1 5.8 33.0 1.4 8.4 4.5 4.8 4 0 0 4 4 4 0 IncA protein Sec1 PF00995.18 EIW66047.1 - 2.9e-148 494.9 0.0 3.4e-148 494.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family RNA_pol_Rpb1_5 PF04998.12 EIW66048.1 - 2.2e-93 312.5 0.4 3.7e-93 311.7 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EIW66048.1 - 1.4e-75 254.6 0.0 2e-75 254.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EIW66048.1 - 1.6e-63 213.5 0.0 2.8e-63 212.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIW66048.1 - 1.7e-37 128.5 0.0 1.1e-36 125.9 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EIW66048.1 - 5.3e-30 103.3 0.0 1.4e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 ADK PF00406.17 EIW66049.1 - 1.1e-42 145.4 0.1 3.5e-41 140.5 0.1 2.1 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EIW66049.1 - 9.6e-09 35.6 0.0 1.4e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW66049.1 - 2.8e-06 28.1 0.0 5.1e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW66049.1 - 9.1e-05 22.3 0.0 0.00051 19.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EIW66049.1 - 0.00058 19.2 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 EIW66049.1 - 0.11 11.6 0.0 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin Translin PF01997.11 EIW66050.1 - 3.6e-49 167.1 0.0 5e-47 160.0 0.0 2.1 1 1 0 1 1 1 1 Translin family Pro_isomerase PF00160.16 EIW66051.1 - 2.3e-41 141.5 0.0 3.5e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EIW66051.1 - 2.1e-08 33.6 0.3 6.2e-06 25.7 0.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EIW66051.1 - 0.0015 18.3 1.7 0.057 13.3 0.2 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW66051.1 - 0.0055 16.2 0.5 0.057 13.0 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW66051.1 - 0.093 12.6 0.4 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TB2_DP1_HVA22 PF03134.14 EIW66053.1 - 1.9e-05 24.2 3.1 3.2e-05 23.5 2.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Vps51 PF08700.6 EIW66056.1 - 4.4e-11 42.4 0.4 1.6e-10 40.6 0.1 2.2 2 0 0 2 2 2 1 Vps51/Vps67 tRNA-synt_1c PF00749.16 EIW66057.1 - 2.7e-87 292.3 0.1 3.5e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EIW66057.1 - 2.5e-37 128.2 0.2 5.4e-37 127.1 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.1 EIW66057.1 - 0.00042 20.1 0.1 0.00093 19.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW66057.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CLN3 PF02487.12 EIW66060.1 - 8.2e-56 189.5 9.5 3.8e-42 144.5 5.1 4.0 3 1 0 3 3 3 3 CLN3 protein ELMO_CED12 PF04727.8 EIW66061.1 - 3.7e-15 55.8 0.0 7.1e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EIW66061.1 - 7e-05 22.5 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) CMAS PF02353.15 EIW66062.1 - 3.7e-29 101.6 0.0 4.9e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EIW66062.1 - 2.7e-12 46.5 0.0 4.6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW66062.1 - 1.5e-08 35.0 0.0 2.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW66062.1 - 5.9e-08 32.5 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW66062.1 - 4.5e-07 29.4 0.0 7.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EIW66062.1 - 1e-06 29.3 0.0 1.9e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW66062.1 - 9.1e-06 25.9 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW66062.1 - 0.00015 22.1 0.0 0.00031 21.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EIW66062.1 - 0.018 14.1 0.0 0.038 13.1 0.0 1.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 EIW66062.1 - 0.019 14.9 0.0 0.065 13.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EIW66062.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ctr PF04145.10 EIW66063.1 - 2.1e-31 108.9 0.0 3.5e-31 108.2 0.0 1.3 1 1 0 1 1 1 1 Ctr copper transporter family TIMELESS PF04821.9 EIW66064.1 - 3.3e-35 121.6 0.5 8.3e-35 120.3 0.4 1.7 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 EIW66064.1 - 6e-11 41.9 0.6 6e-11 41.9 0.4 4.1 3 1 0 3 3 3 2 Timeless protein C terminal region Flu_C_NS2 PF03555.9 EIW66064.1 - 0.003 17.4 0.2 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 Influenza C non-structural protein (NS2) Lactamase_B_2 PF12706.2 EIW66065.1 - 6.8e-32 110.5 0.0 4.3e-31 107.9 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIW66065.1 - 5.3e-13 49.0 0.2 5.8e-12 45.6 0.1 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EIW66065.1 - 5.7e-09 35.3 0.0 3.3e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 tRNase Z endonuclease Peptidase_S28 PF05577.7 EIW66066.1 - 3e-53 180.9 0.0 4.8e-53 180.2 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 NYD-SP28_assoc PF14775.1 EIW66066.1 - 0.075 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain SIR2 PF02146.12 EIW66067.1 - 6.1e-27 94.4 0.0 2.6e-26 92.4 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Scm3 PF10384.4 EIW66068.1 - 1e-12 47.3 0.7 2.1e-12 46.3 0.5 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 DUF1746 PF08508.5 EIW66069.1 - 3.3e-06 27.0 2.3 5e-06 26.4 0.7 1.9 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1746) Nop PF01798.13 EIW66070.1 - 6.2e-54 181.3 1.5 1.4e-53 180.1 1.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EIW66070.1 - 5.9e-28 96.4 0.1 1e-27 95.6 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EIW66070.1 - 7.6e-15 54.8 0.2 7.6e-15 54.8 0.1 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF3437 PF11919.3 EIW66071.1 - 1.2e-24 85.8 0.4 8e-24 83.1 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) GDA1_CD39 PF01150.12 EIW66072.1 - 1.1e-85 287.7 0.0 1.5e-85 287.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family ATG22 PF11700.3 EIW66074.1 - 1.1e-116 390.1 8.9 2.3e-116 389.1 6.2 1.4 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EIW66074.1 - 0.00047 18.9 43.1 0.0074 15.0 16.5 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Robl_LC7 PF03259.12 EIW66076.1 - 5.6e-10 38.6 0.0 6.9e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain Abhydrolase_5 PF12695.2 EIW66077.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Corona_M PF01635.13 EIW66077.1 - 0.078 11.9 1.8 0.13 11.2 1.3 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Ribosomal_L12 PF00542.14 EIW66078.1 - 4.5e-20 71.4 3.1 4.5e-20 71.4 2.1 2.0 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain DUF2267 PF10025.4 EIW66078.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) CDC37_C PF08564.5 EIW66078.1 - 0.26 11.1 5.5 0.94 9.3 1.3 2.2 1 1 1 2 2 2 0 Cdc37 C terminal domain 2-Hacid_dh_C PF02826.14 EIW66079.1 - 2.4e-43 147.3 0.0 3.1e-41 140.4 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW66079.1 - 5.3e-22 77.7 0.0 6.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.1 EIW66079.1 - 0.00084 19.5 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EIW66079.1 - 0.15 12.1 0.1 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAGK_cat PF00781.19 EIW66080.1 - 1.1e-16 60.4 0.1 4e-15 55.3 0.1 2.5 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain FUR PF01475.14 EIW66080.1 - 0.16 11.9 1.9 0.27 11.1 0.5 1.9 1 1 1 2 2 2 0 Ferric uptake regulator family Pkinase PF00069.20 EIW66081.1 - 1.1e-70 237.7 0.0 1.5e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW66081.1 - 2.8e-48 164.2 0.0 4.6e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EIW66081.1 - 6.7e-16 58.4 0.2 2.5e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EIW66081.1 - 2.3e-06 26.7 0.0 8.9e-06 24.8 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EIW66081.1 - 6.1e-05 22.8 0.0 0.031 14.0 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIW66081.1 - 0.00041 19.4 0.0 0.0012 17.9 0.0 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIW66081.1 - 0.015 14.6 0.0 0.061 12.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family zf-RING_2 PF13639.1 EIW66082.1 - 1.1e-07 31.5 3.3 2e-07 30.7 2.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIW66082.1 - 1e-05 25.5 1.3 2.3e-05 24.4 0.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIW66082.1 - 0.004 16.7 2.3 0.0084 15.7 1.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW66082.1 - 0.012 15.2 2.6 0.023 14.4 1.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW66082.1 - 0.018 15.0 1.9 0.049 13.6 1.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EIW66082.1 - 0.022 14.7 1.0 0.05 13.5 0.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Gag_p24 PF00607.15 EIW66082.1 - 0.036 13.6 7.0 0.076 12.5 0.8 3.3 3 1 1 4 4 4 0 gag gene protein p24 (core nucleocapsid protein) RINGv PF12906.2 EIW66082.1 - 0.081 12.9 2.3 0.19 11.7 1.6 1.7 1 0 0 1 1 1 0 RING-variant domain Phage_GP20 PF06810.6 EIW66082.1 - 0.11 11.9 20.5 0.065 12.6 7.0 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 zf-Apc11 PF12861.2 EIW66082.1 - 0.12 12.1 1.0 0.29 10.9 0.7 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prefoldin PF02996.12 EIW66082.1 - 0.25 11.0 17.5 0.8 9.3 3.2 4.1 3 1 1 4 4 4 0 Prefoldin subunit DUF948 PF06103.6 EIW66082.1 - 0.68 9.8 7.8 2 8.3 0.4 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.3 EIW66082.1 - 0.69 9.6 21.8 1.3 8.7 7.3 2.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2935 PF11155.3 EIW66082.1 - 2.5 8.2 12.4 8.7 6.4 0.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Rho_Binding PF08912.6 EIW66082.1 - 2.7 8.3 21.9 11 6.3 1.6 4.1 3 1 0 3 3 3 0 Rho Binding HALZ PF02183.13 EIW66082.1 - 4 7.2 17.0 0.12 12.1 2.8 3.2 2 1 1 3 3 3 0 Homeobox associated leucine zipper Prominin PF05478.6 EIW66082.1 - 6.1 4.2 8.5 3.1 5.2 1.7 2.0 2 0 0 2 2 2 0 Prominin bZIP_Maf PF03131.12 EIW66082.1 - 7.9 6.8 22.5 1.8 8.9 0.5 3.8 2 1 1 3 3 3 0 bZIP Maf transcription factor DUF2681 PF10883.3 EIW66082.1 - 8.9 6.5 9.9 2.6 8.3 2.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ATP11 PF06644.6 EIW66083.1 - 2.2e-66 224.0 0.0 2.6e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Med18 PF09637.5 EIW66084.1 - 0.00076 19.1 0.2 0.0022 17.5 0.0 1.8 2 0 0 2 2 2 1 Med18 protein ThiF PF00899.16 EIW66085.1 - 3.9e-35 120.6 0.0 7e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EIW66085.1 - 2.1e-28 97.6 0.3 4.4e-28 96.6 0.2 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EIW66085.1 - 1.7e-21 75.3 2.2 3e-21 74.5 1.5 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EIW66085.1 - 1.7e-05 24.8 0.0 6.4e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EIW66085.1 - 5.9e-05 23.2 0.0 0.0002 21.5 0.0 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EIW66085.1 - 0.0098 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TFIIB PF00382.14 EIW66086.1 - 1.1e-30 105.2 0.7 6.4e-14 51.5 0.0 3.0 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EIW66086.1 - 5.6e-16 58.5 5.6 5.6e-16 58.5 3.9 3.8 3 1 1 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EIW66086.1 - 0.0052 16.0 0.8 0.012 14.8 0.6 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EIW66086.1 - 0.014 14.9 0.0 0.86 9.1 0.0 2.5 2 0 0 2 2 2 0 Cyclin, N-terminal domain DAGAT PF03982.8 EIW66087.1 - 1.4e-93 312.8 0.0 1.7e-93 312.5 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase MFS_1 PF07690.11 EIW66088.1 - 9.1e-36 123.2 39.5 2.6e-34 118.5 27.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW66088.1 - 1.4e-10 40.3 11.9 1.4e-10 40.3 8.3 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EIW66088.1 - 0.00088 17.7 11.6 0.00088 17.7 8.1 2.6 2 1 1 3 3 3 1 MFS/sugar transport protein MULE PF10551.4 EIW66089.1 - 1.8e-06 27.9 0.8 0.00029 20.9 0.1 3.2 2 1 0 2 2 2 1 MULE transposase domain NHR2 PF08788.6 EIW66089.1 - 0.029 13.8 0.8 0.09 12.2 0.6 1.8 1 0 0 1 1 1 0 NHR2 domain like SR-25 PF10500.4 EIW66090.1 - 0.45 9.9 4.6 0.68 9.3 3.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Abhydrolase_2 PF02230.11 EIW66091.1 - 2.8e-58 196.9 0.0 6.4e-58 195.7 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EIW66091.1 - 4.2e-13 49.7 0.5 2e-11 44.2 0.4 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW66091.1 - 1.4e-10 41.1 0.1 2.6e-10 40.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIW66091.1 - 0.0014 18.1 0.0 0.0067 15.8 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EIW66091.1 - 0.005 16.4 0.0 0.0065 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 EIW66091.1 - 0.0073 16.0 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_3 PF07859.8 EIW66091.1 - 0.0097 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EIW66091.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase LRR_9 PF14580.1 EIW66092.1 - 4.8e-38 130.4 0.0 6.3e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EIW66092.1 - 1e-15 56.9 30.8 1.4e-08 34.1 3.3 3.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW66092.1 - 1.1e-08 34.6 13.4 3.4e-07 29.9 4.7 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EIW66092.1 - 0.0066 16.3 15.4 8.2 6.8 0.0 5.5 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 EIW66092.1 - 0.0069 16.3 8.1 9.6 6.9 0.1 5.2 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EIW66092.1 - 0.031 14.3 12.1 10 6.5 0.9 5.0 5 0 0 5 5 5 0 Leucine Rich repeat Septin PF00735.13 EIW66093.1 - 8.6e-123 408.8 0.1 8.6e-123 408.8 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EIW66093.1 - 1.3e-07 31.5 0.0 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW66093.1 - 6.5e-06 25.4 0.1 2.5e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIW66093.1 - 4.9e-05 23.6 2.7 0.011 16.0 0.0 2.9 2 1 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.22 EIW66093.1 - 0.00024 20.5 2.0 0.0098 15.3 0.0 3.3 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EIW66093.1 - 0.00041 19.5 2.1 0.00048 19.2 0.0 2.1 2 1 0 2 2 2 1 AIG1 family AAA_22 PF13401.1 EIW66093.1 - 0.0014 18.8 0.0 0.0064 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EIW66093.1 - 0.0024 17.7 5.5 0.34 10.7 0.1 3.2 2 1 1 3 3 3 2 Dynamin family AAA_16 PF13191.1 EIW66093.1 - 0.0059 16.6 0.3 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.17 EIW66093.1 - 0.0064 15.8 0.0 0.019 14.3 0.0 1.8 1 0 0 1 1 1 1 Ras family AAA_10 PF12846.2 EIW66093.1 - 0.0077 15.7 0.0 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_23 PF13476.1 EIW66093.1 - 0.01 16.1 1.6 1.8 8.8 1.2 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EIW66093.1 - 0.017 15.6 0.0 0.071 13.6 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EIW66093.1 - 0.032 13.7 0.0 0.09 12.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Exonuc_VII_L PF02601.10 EIW66093.1 - 0.051 12.7 4.8 0.091 11.9 3.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit MobB PF03205.9 EIW66093.1 - 0.062 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EIW66093.1 - 0.1 12.1 1.7 8.7 5.7 0.0 3.2 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein PIH1 PF08190.7 EIW66093.1 - 0.1 11.9 7.3 0.15 11.4 5.1 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 cobW PF02492.14 EIW66093.1 - 0.15 11.4 1.4 4 6.8 0.1 2.7 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EIW66093.1 - 0.24 11.0 4.9 0.44 10.2 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase IncA PF04156.9 EIW66093.1 - 1.3 8.5 6.5 2.4 7.7 4.5 1.4 1 0 0 1 1 1 0 IncA protein Thaumatin PF00314.12 EIW66094.1 - 1.6e-46 158.4 12.4 2.2e-46 158.0 8.6 1.2 1 0 0 1 1 1 1 Thaumatin family SR-25 PF10500.4 EIW66095.1 - 1.3 8.4 31.1 0.11 11.9 9.4 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.18 EIW66096.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66096.1 - 0.27 11.5 9.2 0.069 13.3 4.2 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66096.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF746 PF05344.6 EIW66097.1 - 0.057 12.9 0.2 0.73 9.4 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) DUF605 PF04652.11 EIW66099.1 - 5.2e-66 223.5 0.0 6.1e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Vta1 like DUF1647 PF07801.6 EIW66099.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) SOBP PF15279.1 EIW66100.1 - 1.3 9.3 20.1 2.2 8.6 13.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein GYF PF02213.11 EIW66101.1 - 4e-17 61.5 1.0 9.6e-17 60.3 0.7 1.6 1 0 0 1 1 1 1 GYF domain DUF4339 PF14237.1 EIW66101.1 - 0.61 9.7 4.7 0.15 11.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) PH_10 PF15411.1 EIW66102.1 - 3.3e-28 98.2 0.0 9.9e-28 96.6 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain zf-RING_2 PF13639.1 EIW66102.1 - 0.0004 20.1 2.5 0.001 18.8 1.8 1.7 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIW66102.1 - 0.00086 19.3 1.6 0.016 15.2 1.3 2.4 1 1 1 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIW66102.1 - 0.0012 18.4 0.7 0.003 17.2 0.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain VWA_3 PF13768.1 EIW66102.1 - 0.0046 16.6 0.0 0.029 14.0 0.0 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.1 EIW66102.1 - 0.005 16.4 1.2 0.0097 15.5 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW66102.1 - 0.0071 16.1 0.4 0.014 15.1 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EIW66102.1 - 0.15 12.1 1.4 0.54 10.3 1.0 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW66102.1 - 0.26 10.9 1.1 0.6 9.8 0.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Transp_cyt_pur PF02133.10 EIW66102.1 - 0.49 8.8 0.0 0.72 8.3 0.0 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin APC10 PF03256.11 EIW66103.1 - 3.8e-46 157.1 0.0 4.2e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EIW66103.1 - 0.00017 21.4 0.0 0.00021 21.1 0.0 1.3 1 1 0 1 1 1 1 F5/8 type C domain PYST-C1 PF09690.5 EIW66104.1 - 0.12 12.0 0.2 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) PWWP PF00855.12 EIW66104.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 PWWP domain KAR9 PF08580.5 EIW66105.1 - 0.16 10.2 0.5 0.19 9.9 0.3 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 NPR3 PF03666.8 EIW66106.1 - 1.7e-55 188.3 0.0 1.7e-55 188.3 0.0 2.9 2 2 1 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 zf-HC5HC2H_2 PF13832.1 EIW66107.1 - 3.1e-34 117.2 6.4 3.1e-34 117.2 4.4 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIW66107.1 - 1.9e-27 95.2 2.7 1.9e-27 95.2 1.9 2.8 3 0 0 3 3 2 1 PHD-like zinc-binding domain EPL1 PF10513.4 EIW66107.1 - 2.5e-23 83.0 0.8 2.5e-23 83.0 0.5 3.7 3 2 0 3 3 2 1 Enhancer of polycomb-like dCMP_cyt_deam_1 PF00383.17 EIW66107.1 - 4.5e-21 74.4 0.2 4e-20 71.3 0.0 2.2 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bromodomain PF00439.20 EIW66107.1 - 6.6e-16 58.0 0.1 1.7e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 EIW66107.1 - 1e-14 53.5 3.1 1e-14 53.5 2.2 3.1 3 0 0 3 3 3 1 PHD-finger PWWP PF00855.12 EIW66107.1 - 2.6e-10 40.3 0.0 9.7e-10 38.5 0.0 2.0 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 EIW66107.1 - 4.9e-10 38.9 21.2 6.8e-10 38.4 3.8 3.1 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 EIW66107.1 - 0.0023 17.6 11.7 0.0072 16.0 0.3 2.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 EIW66107.1 - 0.0041 16.4 0.9 0.0041 16.4 0.6 2.5 3 1 0 3 3 1 1 PHD/FYVE-zinc-finger like domain APOBEC_N PF08210.6 EIW66107.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain zf-RING-like PF08746.6 EIW66107.1 - 0.017 15.0 16.6 0.03 14.3 4.7 2.8 2 0 0 2 2 2 0 RING-like domain XOO_2897-deam PF14440.1 EIW66107.1 - 0.019 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Prok-RING_1 PF14446.1 EIW66107.1 - 0.028 14.1 13.5 0.17 11.6 1.7 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Bd3614-deam PF14439.1 EIW66107.1 - 0.03 14.1 2.0 2.4 7.9 0.2 2.9 1 1 1 2 2 2 0 Bd3614-like deaminase ATP-synt_ab PF00006.20 EIW66109.1 - 2.7e-70 236.2 0.0 4.1e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIW66109.1 - 1.3e-23 83.5 0.0 3.4e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIW66109.1 - 8.5e-19 67.5 1.9 2.4e-18 66.0 1.3 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EIW66109.1 - 0.00012 21.8 1.3 0.0003 20.6 0.7 1.9 2 0 0 2 2 2 1 HAS barrel domain Ribosomal_L21p PF00829.16 EIW66110.1 - 2e-06 27.8 0.0 0.00018 21.5 0.3 2.1 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein SPOR PF05036.8 EIW66110.1 - 0.0023 18.0 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 Sporulation related domain Kinesin PF00225.18 EIW66111.1 - 1.5e-99 332.8 0.0 2.8e-99 331.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain TPR_MLP1_2 PF07926.7 EIW66111.1 - 0.0034 17.1 18.6 0.0034 17.1 12.9 2.5 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EIW66111.1 - 0.039 13.1 10.1 0.026 13.7 2.4 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EIW66111.1 - 0.056 13.0 32.9 0.041 13.4 8.0 2.4 1 1 1 2 2 2 0 IncA protein Myosin_tail_1 PF01576.14 EIW66111.1 - 0.34 8.5 35.4 2.2 5.9 0.3 2.0 1 1 1 2 2 2 0 Myosin tail DUF3584 PF12128.3 EIW66111.1 - 2.2 5.5 25.2 3.8 4.7 17.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SPX PF03105.14 EIW66111.1 - 2.8 7.6 9.5 12 5.5 6.5 1.9 1 1 0 1 1 1 0 SPX domain DUF619 PF04768.8 EIW66112.1 - 2.3e-41 141.0 0.0 3.8e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EIW66112.1 - 7.3e-29 100.5 0.0 2.1e-28 99.0 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EIW66112.1 - 9e-20 71.2 0.0 1.6e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EIW66112.1 - 0.037 13.9 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Kdo PF06293.9 EIW66114.1 - 0.00081 18.5 0.1 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PLD_C PF12357.3 EIW66117.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D C terminal Kdo PF06293.9 EIW66118.1 - 0.00038 19.6 0.1 0.00048 19.2 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Drf_DAD PF06345.6 EIW66119.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 DRF Autoregulatory Domain Resolvase PF00239.16 EIW66121.1 - 0.018 14.8 2.6 0.033 14.0 1.8 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain DUF3435 PF11917.3 EIW66122.1 - 1.5e-06 27.2 0.1 1.9e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EIW66122.1 - 0.00053 19.7 0.0 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family Luciferase_N PF05295.6 EIW66122.1 - 0.01 15.6 0.3 2.3 8.0 0.0 2.6 2 0 0 2 2 2 0 Luciferase/LBP N-terminal domain TFIIF_beta PF02270.10 EIW66123.1 - 5.9e-45 154.1 0.0 1.4e-44 152.9 0.0 1.5 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 EIW66123.1 - 0.07 12.4 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit BRCT PF00533.21 EIW66124.1 - 0.0018 18.3 0.1 0.11 12.6 0.0 2.8 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RFX_DNA_binding PF02257.10 EIW66126.1 - 0.062 13.4 0.1 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 RFX DNA-binding domain ENTH PF01417.15 EIW66127.1 - 1.4e-44 150.9 0.1 2e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EIW66127.1 - 0.00057 18.6 0.2 0.00098 17.9 0.0 1.4 2 0 0 2 2 2 1 ANTH domain GlgS PF08971.6 EIW66131.1 - 0.32 10.9 0.0 0.66 9.9 0.0 1.5 1 0 0 1 1 1 0 Glycogen synthesis protein WD40 PF00400.27 EIW66132.1 - 9.6e-68 221.8 18.9 3.9e-10 39.2 0.1 11.4 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 EIW66132.1 - 7e-11 42.0 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EIW66132.1 - 2.6e-07 29.1 1.1 0.0091 14.1 0.0 4.4 5 0 0 5 5 5 2 Nucleoporin Nup120/160 Pol_alpha_B_N PF08418.5 EIW66132.1 - 0.0078 15.7 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal RAB3GAP2_N PF14655.1 EIW66132.1 - 0.053 12.5 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Asp_protease_2 PF13650.1 EIW66135.1 - 1.5e-07 31.7 0.0 3.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIW66135.1 - 2.8e-06 27.0 0.0 1.1e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 EIW66135.1 - 0.00024 20.8 1.8 0.00047 19.9 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EIW66135.1 - 0.0011 18.9 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EIW66135.1 - 0.0025 17.6 0.0 0.0063 16.4 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 EIW66135.1 - 0.0031 16.9 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.1 EIW66135.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.5 EIW66135.1 - 0.093 12.3 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease zf-CCHC_5 PF14787.1 EIW66135.1 - 1.6 8.2 8.6 0.27 10.7 2.9 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.12 EIW66136.1 - 9.7e-06 25.5 0.1 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIW66136.1 - 0.0023 17.7 1.9 0.0039 17.0 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW66136.1 - 0.12 12.0 0.2 0.12 12.0 0.2 2.1 3 0 0 3 3 3 0 Zinc knuckle CagZ PF09053.5 EIW66136.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 CagZ Scs3p PF10261.4 EIW66140.1 - 3.2e-54 183.4 0.0 8.3e-54 182.1 0.0 1.7 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Chitin_synth_2 PF03142.10 EIW66141.1 - 1.9e-259 861.4 0.4 2.6e-259 861.0 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIW66141.1 - 1.5e-17 63.9 3.1 2.1e-17 63.4 1.2 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW66141.1 - 4.5e-15 56.0 0.0 1e-13 51.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIW66141.1 - 5.4e-11 42.1 0.0 4.7e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EIW66141.1 - 2.9e-05 23.4 0.1 0.0001 21.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EIW66141.1 - 0.00041 20.0 0.0 0.0056 16.3 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF2587 PF10759.4 EIW66144.1 - 0.02 14.2 0.1 0.058 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW66145.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66145.1 - 0.44 10.8 7.2 0.12 12.6 2.8 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Radial_spoke_3 PF06098.6 EIW66145.1 - 0.45 9.4 7.7 0.97 8.3 2.4 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 B56 PF01603.15 EIW66145.1 - 0.84 8.1 2.8 1.1 7.7 1.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.20 EIW66147.1 - 2.6e-74 249.6 0.0 3.2e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW66147.1 - 6.5e-39 133.5 0.0 8.2e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW66147.1 - 3.8e-06 26.0 0.0 2.8e-05 23.2 0.0 2.3 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EIW66147.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EIW66147.1 - 0.0017 17.6 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EIW66147.1 - 0.0037 16.3 0.1 0.015 14.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family CaATP_NAI PF12515.3 EIW66147.1 - 0.52 9.8 2.3 0.75 9.3 0.8 1.8 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain DUF1349 PF07081.6 EIW66148.1 - 4.9e-20 71.6 0.4 4.9e-19 68.4 0.3 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) Hexapep PF00132.19 EIW66149.1 - 3.6e-13 48.3 16.9 3.5e-11 42.0 4.9 3.9 5 0 0 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIW66149.1 - 4.6e-12 45.2 9.2 1.6e-09 37.1 4.8 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EIW66149.1 - 1.4e-05 25.0 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase eIF-1a PF01176.14 EIW66150.1 - 2.7e-26 90.7 0.2 3.6e-26 90.3 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF1985 PF09331.6 EIW66150.1 - 0.15 11.9 0.2 11 5.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1985) PPR_2 PF13041.1 EIW66151.1 - 2.1e-39 133.2 0.2 1.4e-12 47.3 0.0 10.3 8 1 2 10 10 10 7 PPR repeat family PPR PF01535.15 EIW66151.1 - 1.3e-30 103.1 6.9 8.9e-06 25.3 0.0 11.5 13 0 0 13 13 12 4 PPR repeat PPR_3 PF13812.1 EIW66151.1 - 2.7e-30 102.0 2.0 0.00046 20.2 0.0 11.5 13 0 0 13 13 13 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIW66151.1 - 5.9e-21 73.6 0.0 4.4e-06 26.0 0.0 6.9 9 0 0 9 9 9 3 PPR repeat zf-C3HC4_3 PF13920.1 EIW66151.1 - 5e-06 26.0 6.5 0.00057 19.5 3.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW66151.1 - 8.2e-06 25.4 4.8 8.2e-06 25.4 3.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW66151.1 - 1.9e-05 24.5 6.1 1.9e-05 24.5 4.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW66151.1 - 5.4e-05 22.7 4.5 0.00015 21.3 3.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW66151.1 - 0.00011 21.9 7.3 0.0003 20.5 2.6 2.4 2 0 0 2 2 2 1 Ring finger domain TPR_14 PF13428.1 EIW66151.1 - 0.021 15.4 0.0 5.3 7.9 0.1 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-RING_UBOX PF13445.1 EIW66151.1 - 0.77 9.5 14.6 0.0064 16.1 4.0 2.2 2 0 0 2 2 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EIW66151.1 - 1.6 8.6 13.5 0.015 15.1 3.9 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING SR-25 PF10500.4 EIW66152.1 - 0.017 14.6 3.2 0.019 14.4 2.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DDHD PF02862.12 EIW66152.1 - 0.76 9.5 4.0 1.2 8.8 2.8 1.4 1 1 0 1 1 1 0 DDHD domain Apolipoprotein PF01442.13 EIW66155.1 - 0.0091 15.5 0.1 0.052 13.0 0.0 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3679 PF12438.3 EIW66155.1 - 0.089 12.1 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3679) DUF883 PF05957.8 EIW66155.1 - 0.11 12.8 2.3 7.5 7.0 1.4 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.5 EIW66155.1 - 1.4 8.8 11.4 2 8.4 0.5 4.1 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phasin_2 PF09361.5 EIW66155.1 - 3 7.9 7.6 22 5.1 3.4 3.4 2 1 1 3 3 3 0 Phasin protein Herpes_gE PF02480.11 EIW66156.1 - 0.008 14.4 0.0 0.008 14.4 0.0 1.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E eIF3g PF12353.3 EIW66162.1 - 0.002 18.0 0.4 0.0073 16.2 0.3 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Methyltransf_16 PF10294.4 EIW66165.1 - 1.3e-06 28.0 0.0 6.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 EIW66165.1 - 0.00036 20.1 0.0 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW66165.1 - 0.0061 17.1 0.0 3.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EIW66165.1 - 0.017 15.1 0.0 0.19 11.7 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EIW66165.1 - 0.15 11.7 0.0 0.54 9.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Apis_Csd PF11671.3 EIW66166.1 - 3.8 7.3 6.5 23 4.7 1.5 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein NAC PF01849.13 EIW66167.1 - 5e-18 64.3 0.1 7.9e-18 63.7 0.1 1.3 1 0 0 1 1 1 1 NAC domain Ribosomal_60s PF00428.14 EIW66167.1 - 0.0081 16.5 1.3 0.0081 16.5 0.9 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein TPR_10 PF13374.1 EIW66169.1 - 9.4 6.3 8.9 3.3 7.7 0.6 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat DDE_1 PF03184.14 EIW66170.1 - 9.1e-26 90.3 0.0 1.3e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW66170.1 - 3.3e-06 26.9 0.0 5.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EIW66170.1 - 2.4e-05 23.7 0.4 5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EIW66170.1 - 5.2e-05 22.9 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF1295 PF06966.7 EIW66172.1 - 2.3e-40 138.3 0.0 2.7e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EIW66172.1 - 0.00015 21.8 0.1 0.00049 20.2 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW66172.1 - 0.016 15.2 0.1 0.062 13.4 0.0 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase Steroid_dh PF02544.11 EIW66172.1 - 0.056 13.2 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2587 PF10759.4 EIW66174.1 - 0.11 11.9 0.1 0.27 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW66175.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66175.1 - 0.65 10.2 6.8 0.18 12.0 2.6 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF4341 PF14241.1 EIW66177.1 - 0.013 15.1 0.1 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4341) TFIIA PF03153.8 EIW66178.1 - 0.048 13.5 14.1 0.067 13.0 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EIW66178.1 - 0.22 9.4 18.6 0.26 9.1 12.9 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EIW66178.1 - 0.5 10.0 16.5 0.77 9.4 11.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 EIW66178.1 - 1.2 7.5 16.8 1.7 7.0 11.6 1.2 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 EIW66178.1 - 1.8 8.0 16.1 3.8 7.0 11.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 EIW66178.1 - 2 7.5 11.8 2.9 7.0 8.2 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 EIW66178.1 - 5.2 4.9 15.5 3.1 5.7 9.6 1.4 2 0 0 2 2 2 0 CDC45-like protein TRAP_alpha PF03896.11 EIW66178.1 - 8 5.3 12.3 15 4.4 8.5 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Gcd10p PF04189.8 EIW66179.1 - 0.089 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Gcd10p family GET2 PF08690.5 EIW66179.1 - 0.23 10.6 2.4 0.4 9.8 1.7 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 dsDNA_bind PF01984.15 EIW66180.1 - 2e-25 88.8 0.3 2.7e-25 88.4 0.2 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain WD40 PF00400.27 EIW66181.1 - 5.6e-62 203.5 23.5 4.6e-11 42.1 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW66181.1 - 5.8e-06 24.7 6.4 0.012 13.7 0.2 3.4 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIW66181.1 - 0.011 14.0 0.0 0.59 8.3 0.0 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF1513 PF07433.6 EIW66181.1 - 0.015 14.2 0.0 1.1 8.0 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) IKI3 PF04762.7 EIW66181.1 - 0.11 10.2 0.0 2.9 5.5 0.0 2.4 2 1 1 3 3 3 0 IKI3 family PNPOx_C PF10590.4 EIW66182.1 - 1.4e-20 72.4 6.0 2.3e-20 71.7 4.2 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EIW66182.1 - 6.1e-16 58.2 0.0 1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EIW66182.1 - 2.9e-06 27.5 0.0 5.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Myb_DNA-bind_5 PF13873.1 EIW66182.1 - 0.056 13.3 0.1 0.39 10.6 0.0 2.1 1 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Imm45 PF15603.1 EIW66182.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 45 Noc2 PF03715.8 EIW66183.1 - 2.2e-104 348.5 0.0 4.6e-104 347.4 0.0 1.6 1 0 0 1 1 1 1 Noc2p family PI3K_1B_p101 PF10486.4 EIW66183.1 - 8.6 3.7 7.6 14 3.0 5.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit amfpi-1 PF12190.3 EIW66184.1 - 0.12 12.9 0.2 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 Fungal protease inhibitor YwqJ-deaminase PF14431.1 EIW66184.1 - 0.13 12.1 0.3 0.31 10.9 0.2 1.8 1 1 0 1 1 1 0 YwqJ-like deaminase Ank_4 PF13637.1 EIW66193.1 - 1.9e-14 53.6 0.7 2.5e-07 30.9 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIW66193.1 - 3.7e-13 49.6 0.6 4.9e-12 46.0 0.6 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIW66193.1 - 3.8e-13 49.2 0.7 2.2e-08 34.0 0.2 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EIW66193.1 - 9.4e-13 47.2 0.1 1.7e-05 24.3 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EIW66193.1 - 5.2e-09 35.4 0.1 0.0006 19.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Whi5 PF08528.6 EIW66193.1 - 0.029 13.9 0.8 5.8 6.6 0.0 3.2 3 0 0 3 3 3 0 Whi5 like CAP_N PF01213.14 EIW66193.1 - 0.064 12.5 4.4 0.042 13.1 1.4 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EIW66193.1 - 2.4 7.4 7.1 1.9 7.8 3.7 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator NAD_binding_2 PF03446.10 EIW66194.1 - 3.3e-17 62.8 0.0 4.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EIW66194.1 - 3.2e-05 24.0 0.0 0.00022 21.3 0.0 2.0 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EIW66194.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.1 EIW66194.1 - 0.05 13.6 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EIW66194.1 - 0.084 13.3 0.0 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EIW66194.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Archease PF01951.11 EIW66194.1 - 0.13 12.2 0.3 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Archease protein family (MTH1598/TM1083) 3HCDH_N PF02737.13 EIW66194.1 - 0.16 11.6 0.1 19 4.8 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TBP PF00352.16 EIW66195.1 - 2.6e-68 225.3 0.2 1.4e-33 114.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EIW66195.1 - 0.00024 21.0 2.0 0.84 9.7 0.0 3.1 3 1 0 3 3 3 2 Domain of unknown function (DUF3378) FMO-like PF00743.14 EIW66196.1 - 5.3e-28 97.5 0.3 4.2e-11 41.7 0.0 4.1 4 0 0 4 4 4 4 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW66196.1 - 7.9e-07 29.3 0.0 1.4e-05 25.2 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW66196.1 - 0.0013 17.7 0.1 0.073 11.9 0.0 2.7 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FerA PF08165.6 EIW66196.1 - 0.12 12.0 0.1 0.34 10.6 0.1 1.7 1 0 0 1 1 1 0 FerA (NUC095) domain NAD_binding_9 PF13454.1 EIW66196.1 - 0.13 12.0 0.0 0.61 9.8 0.0 2.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding Baculo_gp41 PF04700.7 EIW66196.1 - 0.24 10.8 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region FMO-like PF00743.14 EIW66197.1 - 8.2e-40 136.4 0.1 8.6e-26 90.2 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW66197.1 - 4.6e-11 43.1 0.0 4.1e-10 40.0 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW66197.1 - 3.1e-09 36.7 0.1 2.1e-08 34.0 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EIW66197.1 - 3.7e-08 32.6 1.8 8.4e-06 24.9 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIW66197.1 - 1.9e-05 24.6 0.0 0.00011 22.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW66197.1 - 7.4e-05 22.7 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF775 PF05603.7 EIW66198.1 - 4.4e-45 153.7 0.0 5e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) SKG6 PF08693.5 EIW66199.1 - 2.9 7.3 11.7 0.011 15.0 1.6 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain BTB PF00651.26 EIW66200.1 - 1.9e-05 24.6 0.1 3.4e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-CCHC PF00098.18 EIW66201.1 - 0.00015 21.5 2.0 0.00023 20.9 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIW66201.1 - 0.0075 15.7 0.1 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66201.1 - 0.034 14.3 5.4 0.059 13.5 3.7 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain eIF3g PF12353.3 EIW66201.1 - 0.035 14.0 3.0 0.064 13.1 2.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF3897 PF13036.1 EIW66201.1 - 0.11 12.1 0.6 0.17 11.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3897) zf-CCHC_5 PF14787.1 EIW66201.1 - 6.8 6.2 8.5 0.77 9.2 2.2 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Ribosomal_L15e PF00827.12 EIW66203.1 - 6.9e-90 299.7 10.0 8.4e-90 299.4 6.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Mito_carr PF00153.22 EIW66204.1 - 1.2e-62 207.6 2.2 7.9e-21 73.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EIW66204.1 - 2.1e-09 36.4 0.5 4.6e-06 26.0 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EIW66204.1 - 4.5e-09 34.9 0.4 4e-06 25.7 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EIW66204.1 - 9.7e-08 32.0 1.3 2.8e-07 30.5 0.9 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EIW66204.1 - 3.3e-06 26.1 0.6 1.4e-05 24.1 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EIW66204.1 - 0.0013 18.2 1.6 0.024 14.2 0.4 2.9 2 1 1 3 3 3 2 EF-hand domain pair zf-RING_2 PF13639.1 EIW66205.1 - 4.7e-10 39.1 7.7 7.8e-10 38.4 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW66205.1 - 1.7e-07 31.1 8.4 2.7e-07 30.4 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIW66205.1 - 2.2e-07 30.8 5.6 4.9e-07 29.7 3.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIW66205.1 - 3.4e-07 29.8 4.9 5.8e-07 29.0 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW66205.1 - 5.7e-06 25.9 6.1 9.4e-06 25.2 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW66205.1 - 2.1e-05 24.1 5.2 3.5e-05 23.4 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIW66205.1 - 0.007 16.2 7.1 0.014 15.2 4.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 EIW66205.1 - 0.054 12.9 5.7 0.22 11.0 0.4 2.3 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_6 PF14835.1 EIW66205.1 - 0.11 12.2 5.5 0.22 11.3 3.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EIW66205.1 - 0.16 11.7 3.3 0.33 10.8 2.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EIW66205.1 - 1.1 9.0 6.8 0.26 11.0 2.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 EIW66205.1 - 5 6.7 8.5 10 5.7 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF676 PF05057.9 EIW66206.1 - 1e-31 109.9 0.0 1.5e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EIW66206.1 - 2.4e-05 23.9 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIW66206.1 - 0.0014 18.4 0.0 0.0033 17.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EIW66206.1 - 0.0041 16.7 0.0 0.01 15.4 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein UPF0227 PF05728.7 EIW66206.1 - 0.052 13.2 0.0 0.22 11.2 0.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.15 EIW66206.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Methyltransf_20 PF12147.3 EIW66206.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TmoB PF06234.7 EIW66206.1 - 0.13 12.1 0.0 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) FSH1 PF03959.8 EIW66206.1 - 0.14 11.6 0.0 1 8.7 0.0 2.2 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Vinculin PF01044.14 EIW66206.1 - 0.24 9.3 0.2 0.33 8.8 0.1 1.1 1 0 0 1 1 1 0 Vinculin family Amidohydro_1 PF01979.15 EIW66207.1 - 2.9e-15 56.7 0.4 4.1e-15 56.2 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIW66207.1 - 1.6e-11 44.7 0.9 2.9e-11 43.9 0.6 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EIW66207.1 - 3.9e-11 42.5 0.0 9e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EIW66207.1 - 3.1e-05 23.3 0.3 0.001 18.4 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family IF2_N PF04760.10 EIW66207.1 - 0.063 12.9 0.4 5.9 6.6 0.0 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region GHL6 PF14871.1 EIW66207.1 - 0.08 12.9 0.0 6.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 FAA_hydrolase PF01557.13 EIW66208.1 - 1.1e-61 208.1 0.0 1.3e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 EIW66209.1 - 2.8e-36 125.5 0.0 3.3e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW66209.1 - 3.9e-21 75.6 0.0 4.8e-17 62.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW66209.1 - 2.4e-17 63.0 0.0 4.1e-17 62.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW66209.1 - 6.1e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EIW66209.1 - 3.8e-05 24.0 0.0 6.8e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EIW66209.1 - 7e-05 22.5 0.0 0.00016 21.3 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Ndr PF03096.9 EIW66209.1 - 7.2e-05 21.3 0.0 0.00014 20.4 0.0 1.4 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.6 EIW66209.1 - 0.00032 19.8 0.0 0.018 14.1 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.8 EIW66209.1 - 0.0016 18.0 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase DUF676 PF05057.9 EIW66209.1 - 0.0025 17.1 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) FSH1 PF03959.8 EIW66209.1 - 0.011 15.1 0.0 0.12 11.7 0.0 2.3 2 1 0 2 2 2 0 Serine hydrolase (FSH1) DUF2305 PF10230.4 EIW66209.1 - 0.028 13.8 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 EIW66209.1 - 0.052 12.9 0.1 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 EIW66209.1 - 0.088 12.2 0.0 9.9 5.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LCAT PF02450.10 EIW66209.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Grp1_Fun34_YaaH PF01184.14 EIW66210.1 - 1.4e-28 99.6 9.0 3.2e-18 65.7 3.1 2.0 2 0 0 2 2 2 2 GPR1/FUN34/yaaH family DUF4395 PF14340.1 EIW66210.1 - 0.47 10.5 14.0 3.4 7.7 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) SLIDE PF09111.5 EIW66211.1 - 0.0017 18.1 0.3 0.0032 17.1 0.2 1.4 1 0 0 1 1 1 1 SLIDE F-box-like PF12937.2 EIW66214.1 - 0.0003 20.4 0.1 0.00081 19.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.19 EIW66215.1 - 1.1e-21 76.9 24.3 1.4e-19 70.0 16.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3648 PF12364.3 EIW66217.1 - 0.14 12.1 6.7 0.072 13.0 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3648) Sigma70_r4_2 PF08281.7 EIW66217.1 - 0.16 11.4 0.1 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 F-box-like PF12937.2 EIW66222.1 - 0.00073 19.2 0.1 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like Tim54 PF11711.3 EIW66222.1 - 0.014 14.0 0.5 0.014 14.0 0.4 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 EIW66222.1 - 0.023 12.6 24.2 0.03 12.2 16.7 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 EIW66222.1 - 0.099 10.7 5.9 0.15 10.1 4.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 EIW66222.1 - 0.26 10.6 13.4 0.39 10.0 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EIW66222.1 - 0.44 8.5 16.8 0.61 8.0 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 EIW66222.1 - 0.85 8.2 17.9 1.2 7.7 12.4 1.1 1 0 0 1 1 1 0 Paf1 DUF2722 PF10846.3 EIW66222.1 - 1.1 8.1 3.9 1.6 7.6 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TRAP_alpha PF03896.11 EIW66222.1 - 5.3 5.9 15.1 8.4 5.2 10.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BTV_NS2 PF04514.7 EIW66222.1 - 5.8 5.6 12.9 9.5 4.9 9.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 BUD22 PF09073.5 EIW66222.1 - 8.1 5.3 20.5 12 4.8 14.2 1.1 1 0 0 1 1 1 0 BUD22 Fungal_trans PF04082.13 EIW66223.1 - 4e-15 55.4 0.0 9.4e-15 54.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW66223.1 - 0.33 10.9 14.1 0.78 9.7 9.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Lung_7-TM_R PF06814.8 EIW66224.1 - 8e-56 189.1 14.9 1.1e-55 188.7 10.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Polysacc_deac_1 PF01522.16 EIW66226.1 - 1.2e-06 28.1 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.16 EIW66227.1 - 1.2e-08 34.6 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Tbf5 PF06331.7 EIW66228.1 - 0.089 12.5 0.3 0.41 10.4 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 DUF3886 PF13025.1 EIW66228.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) F-box-like PF12937.2 EIW66228.1 - 0.13 11.9 1.1 0.25 11.1 0.8 1.5 1 0 0 1 1 1 0 F-box-like Pex14_N PF04695.8 EIW66229.1 - 0.31 11.0 3.6 0.38 10.8 2.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GPI PF06560.6 EIW66230.1 - 0.18 10.8 0.1 0.29 10.1 0.1 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) RTA1 PF04479.8 EIW66231.1 - 1.6e-40 139.0 4.8 2.6e-40 138.3 3.3 1.3 1 0 0 1 1 1 1 RTA1 like protein RhoGEF PF00621.15 EIW66232.1 - 3.7e-37 127.9 0.0 6.5e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 EIW66232.1 - 9.5e-21 72.9 0.4 8.9e-11 41.0 0.0 3.2 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EIW66232.1 - 5e-19 67.6 3.9 4.4e-11 42.1 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain EF-hand_4 PF12763.2 EIW66232.1 - 1.8e-17 62.9 0.0 3.8e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.12 EIW66232.1 - 6.3e-11 41.5 0.0 0.00021 20.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 EIW66232.1 - 9.7e-09 34.5 1.9 2e-08 33.5 0.4 2.3 2 0 0 2 2 2 1 WH2 motif DUF1720 PF08226.6 EIW66232.1 - 7.2e-07 29.1 106.4 0.00028 20.8 21.2 5.7 3 1 2 5 5 5 3 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 EIW66232.1 - 0.00014 21.9 0.0 0.0005 20.1 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair PH PF00169.24 EIW66232.1 - 0.0003 20.9 0.0 0.00084 19.5 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.1 EIW66232.1 - 0.023 14.5 0.0 2.3 8.3 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 EIW66232.1 - 1.8 8.0 11.8 0.71 9.3 0.1 3.6 5 0 0 5 5 4 0 EF hand DUF605 PF04652.11 EIW66233.1 - 1.8 7.9 15.2 2.1 7.6 10.5 1.1 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 EIW66233.1 - 2.8 6.5 12.7 3.3 6.2 8.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cupin_7 PF12973.2 EIW66234.1 - 1.5e-05 24.6 0.0 0.00015 21.5 0.0 2.1 2 0 0 2 2 2 1 ChrR Cupin-like domain HhH-GPD PF00730.20 EIW66237.1 - 5.5e-20 71.6 0.0 7.2e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EIW66237.1 - 3.4e-06 26.4 0.1 9.7e-06 25.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif DEAD PF00270.24 EIW66238.1 - 2.3e-36 124.8 0.1 2.6e-34 118.1 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW66238.1 - 6.3e-24 83.6 0.2 1.3e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW66238.1 - 4.6e-06 26.5 0.0 7.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW66238.1 - 0.0031 17.6 0.2 0.013 15.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain T4SS-DNA_transf PF02534.9 EIW66238.1 - 0.13 10.7 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer CMS1 PF14617.1 EIW66238.1 - 0.36 9.8 0.0 0.36 9.8 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit zf-CCHC PF00098.18 EIW66241.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66241.1 - 0.26 11.5 9.1 0.069 13.3 4.2 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66241.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW66242.1 - 0.12 11.8 0.1 0.3 10.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) SR-25 PF10500.4 EIW66242.1 - 0.3 10.5 29.3 0.082 12.3 9.1 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Packaging_FI PF14000.1 EIW66243.1 - 0.041 14.0 0.2 0.051 13.7 0.1 1.1 1 0 0 1 1 1 0 DNA packaging protein FI DUF2562 PF10814.3 EIW66243.1 - 0.055 13.4 0.1 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) DUF605 PF04652.11 EIW66244.1 - 1.8 7.9 10.3 2.2 7.5 7.2 1.3 1 0 0 1 1 1 0 Vta1 like Tad PF13400.1 EIW66245.1 - 0.16 12.0 1.5 0.24 11.4 1.1 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Cupin_2 PF07883.6 EIW66246.1 - 0.0003 20.2 0.1 0.0022 17.4 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EIW66246.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Cupin ThiF PF00899.16 EIW66247.1 - 3.8e-38 130.3 0.0 1.2e-37 128.7 0.0 1.7 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EIW66247.1 - 3.4e-25 87.4 0.2 6.3e-25 86.5 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EIW66247.1 - 3.6e-22 77.9 0.0 6.9e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EIW66247.1 - 8.8e-17 60.2 3.1 1.7e-16 59.3 2.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EIW66247.1 - 0.00069 19.1 0.7 0.0029 17.1 0.0 2.1 2 0 0 2 2 2 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 EIW66247.1 - 0.0014 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EIW66247.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Adeno_PVIII PF01310.13 EIW66247.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII Ecm33 PF12454.3 EIW66247.1 - 0.11 12.4 1.0 0.25 11.2 0.7 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein GATase PF00117.23 EIW66248.1 - 9.3e-10 38.2 0.0 1.6e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIW66248.1 - 0.0027 17.1 0.5 0.0068 15.8 0.3 2.0 1 1 0 1 1 1 1 Peptidase C26 DLH PF01738.13 EIW66248.1 - 0.09 12.0 0.1 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Vps51 PF08700.6 EIW66249.1 - 4.7e-14 51.9 0.1 7.3e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EIW66249.1 - 0.017 15.1 0.2 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.7 EIW66249.1 - 0.2 11.4 1.5 0.53 10.1 1.0 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DEAD PF00270.24 EIW66250.1 - 1.6e-37 128.5 0.0 3.4e-37 127.5 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW66250.1 - 1.3e-18 66.6 0.0 3.1e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW66250.1 - 2.8e-09 37.0 0.0 5.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF601 PF04642.7 EIW66250.1 - 0.0023 17.3 4.4 0.0042 16.5 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF601 AAA_22 PF13401.1 EIW66250.1 - 0.03 14.4 0.1 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain EVE PF01878.13 EIW66251.1 - 4.5e-47 159.6 0.0 6.5e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 EVE domain Bax1-I PF01027.15 EIW66252.1 - 2.7 7.5 33.5 10 5.6 10.8 2.1 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Peptidase_M41 PF01434.13 EIW66253.1 - 3.9e-70 235.6 0.3 6.1e-70 235.0 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EIW66253.1 - 5.7e-42 143.0 0.0 1.2e-41 142.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW66253.1 - 2.8e-05 24.2 0.1 0.0027 17.8 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW66253.1 - 8.8e-05 23.3 0.0 0.00028 21.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EIW66253.1 - 0.00015 21.4 0.1 0.00061 19.4 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIW66253.1 - 0.00017 21.6 1.1 0.0012 18.8 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EIW66253.1 - 0.0003 19.9 0.0 0.00065 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIW66253.1 - 0.00032 20.4 0.1 0.0015 18.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EIW66253.1 - 0.00057 18.7 0.0 0.0011 17.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EIW66253.1 - 0.0015 18.0 1.2 0.029 13.7 0.3 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EIW66253.1 - 0.002 17.5 0.0 0.0055 16.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIW66253.1 - 0.0047 16.0 0.1 0.014 14.4 0.1 1.8 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EIW66253.1 - 0.0056 15.8 0.5 0.012 14.7 0.3 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EIW66253.1 - 0.0076 15.9 0.2 0.12 12.0 0.0 2.6 3 0 0 3 3 2 1 NACHT domain AAA_2 PF07724.9 EIW66253.1 - 0.0081 16.0 0.0 0.027 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 EIW66253.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW66253.1 - 0.015 15.6 0.1 0.077 13.3 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 EIW66253.1 - 0.015 15.2 0.0 0.088 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIW66253.1 - 0.023 14.5 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW66253.1 - 0.045 12.6 0.0 0.096 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Orbi_VP5 PF00901.12 EIW66253.1 - 0.054 11.6 1.4 0.087 11.0 1.0 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 AdoHcyase_NAD PF00670.16 EIW66253.1 - 0.18 11.6 0.1 7.4 6.3 0.0 2.6 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AhpC-TSA PF00578.16 EIW66254.1 - 3.9e-20 71.7 0.0 7e-20 70.9 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EIW66254.1 - 2.5e-10 40.0 0.0 3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF383 PF04063.9 EIW66255.1 - 1.3e-53 181.3 0.0 2.4e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EIW66255.1 - 1.5e-19 69.2 0.2 3.2e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) SQS_PSY PF00494.14 EIW66257.1 - 1.6e-13 50.6 0.2 3.1e-06 26.6 0.0 2.0 2 0 0 2 2 2 2 Squalene/phytoene synthase DUF4604 PF15377.1 EIW66258.1 - 3.1e-20 72.9 9.8 3.8e-20 72.7 6.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) OstA PF03968.9 EIW66258.1 - 0.078 12.9 0.5 0.14 12.1 0.4 1.3 1 0 0 1 1 1 0 OstA-like protein Methyltransf_11 PF08241.7 EIW66259.1 - 1.9e-14 53.8 0.0 6.3e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW66259.1 - 1.9e-12 47.0 0.0 3.4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW66259.1 - 3.7e-08 33.9 0.0 5.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW66259.1 - 2.4e-07 30.6 0.0 9.1e-07 28.7 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW66259.1 - 1.9e-06 28.2 0.0 3.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW66259.1 - 4.4e-06 26.9 0.0 9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW66259.1 - 7.8e-06 25.3 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EIW66259.1 - 8.5e-05 21.7 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 EIW66259.1 - 0.033 13.3 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EIW66259.1 - 0.075 13.0 0.0 2 8.4 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EIW66259.1 - 0.081 11.7 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.14 EIW66259.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase tRNA_U5-meth_tr PF05958.6 EIW66259.1 - 0.21 10.2 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase RabGAP-TBC PF00566.13 EIW66260.1 - 1.3e-38 132.6 3.4 4.3e-37 127.6 0.4 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Sec23_trunk PF04811.10 EIW66261.1 - 4.3e-45 153.9 0.0 6.8e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIW66261.1 - 7.7e-25 86.3 0.6 1.7e-24 85.2 0.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EIW66261.1 - 6.9e-18 63.9 2.7 1.3e-17 63.0 1.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EIW66261.1 - 5.6e-17 62.0 0.0 9.7e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EIW66261.1 - 0.0072 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat GHL6 PF14871.1 EIW66262.1 - 0.0058 16.6 0.1 0.012 15.5 0.0 1.6 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 RIO1 PF01163.17 EIW66263.1 - 5.1e-47 159.6 0.3 1.2e-46 158.4 0.2 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EIW66263.1 - 4.2e-31 106.8 0.0 9.6e-31 105.6 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EIW66263.1 - 1.3e-09 38.1 0.8 0.0002 21.1 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIW66263.1 - 4.3e-07 29.1 0.0 8.6e-06 24.9 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EIW66263.1 - 0.0055 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) TrmB PF01978.14 EIW66263.1 - 0.0093 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 EIW66263.1 - 0.047 13.3 0.1 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 MarR family Phage_rep_O PF04492.8 EIW66263.1 - 0.072 13.3 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage replication protein O Kinase-like PF14531.1 EIW66263.1 - 0.094 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Daxx PF03344.10 EIW66263.1 - 5.9 5.2 20.2 7.9 4.8 14.0 1.1 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 EIW66263.1 - 7 4.6 10.8 9.6 4.1 7.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PLA2_B PF01735.13 EIW66264.1 - 3.3e-126 421.3 0.7 3.9e-126 421.0 0.5 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain UcrQ PF02939.11 EIW66266.1 - 8.9e-25 86.3 0.6 1.1e-24 86.0 0.4 1.1 1 0 0 1 1 1 1 UcrQ family WD40 PF00400.27 EIW66267.1 - 1.7e-35 119.5 0.0 9.4e-09 34.8 0.0 6.2 5 1 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIW66267.1 - 6e-06 25.2 0.0 0.26 9.9 0.0 3.0 1 1 2 3 3 3 3 Nup133 N terminal like Nup160 PF11715.3 EIW66267.1 - 0.0003 19.0 0.0 0.00038 18.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIW66267.1 - 0.06 12.8 0.5 0.51 9.7 0.3 1.8 1 1 2 3 3 3 0 PQQ-like domain ADH_zinc_N PF00107.21 EIW66268.1 - 2.8e-20 72.1 0.0 1.1e-19 70.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW66268.1 - 0.00068 20.5 0.0 0.0023 18.8 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase zf-C3HC4_2 PF13923.1 EIW66269.1 - 4.5e-08 32.9 6.7 4.5e-08 32.9 4.7 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW66269.1 - 3.7e-07 29.7 5.9 3.7e-07 29.7 4.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW66269.1 - 7.8e-06 25.6 8.7 7.8e-06 25.6 6.0 2.4 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EIW66269.1 - 1.5e-05 24.6 7.2 1.5e-05 24.6 5.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW66269.1 - 2e-05 24.1 7.4 2e-05 24.1 5.1 2.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW66269.1 - 2.4e-05 24.1 4.8 2.4e-05 24.1 3.4 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIW66269.1 - 0.0028 17.3 3.8 0.008 15.8 2.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Spc7 PF08317.6 EIW66269.1 - 0.88 8.1 9.0 1.4 7.5 6.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FYVE PF01363.16 EIW66269.1 - 2 8.3 10.5 0.39 10.6 2.8 2.6 2 0 0 2 2 2 0 FYVE zinc finger IncA PF04156.9 EIW66269.1 - 2 7.9 10.4 0.19 11.3 2.4 2.2 2 0 0 2 2 2 0 IncA protein KH_1 PF00013.24 EIW66270.1 - 0.00018 21.0 1.3 0.00034 20.1 0.9 1.4 1 0 0 1 1 1 1 KH domain Sugar_tr PF00083.19 EIW66271.1 - 3.4e-99 332.4 24.3 3.9e-99 332.2 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW66271.1 - 2.2e-19 69.3 40.2 7.1e-17 61.1 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW66271.1 - 1.2e-07 30.4 16.4 0.00017 20.1 0.2 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.15 EIW66271.1 - 0.52 8.3 7.9 0.15 10.0 1.4 2.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4097 PF13349.1 EIW66271.1 - 1.2 8.6 2.6 0.92 9.0 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) FAD_binding_7 PF03441.9 EIW66272.1 - 3.5e-89 298.6 0.0 5.9e-89 297.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EIW66272.1 - 4.5e-34 117.5 0.1 7.9e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase SOG2 PF10428.4 EIW66273.1 - 3.7e-84 282.9 15.8 3.7e-84 282.9 10.9 3.4 2 2 1 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 EIW66273.1 - 5.2e-12 45.0 17.7 4.3e-06 26.2 0.2 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW66273.1 - 3.8e-11 42.5 5.2 9.7e-07 28.4 1.1 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EIW66273.1 - 1.5e-09 36.5 3.5 0.099 12.7 0.1 5.4 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EIW66273.1 - 0.00012 21.6 8.2 3.6 8.1 0.1 5.4 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EIW66273.1 - 0.5 10.5 5.1 54 4.3 0.2 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Nucleopor_Nup85 PF07575.8 EIW66274.1 - 7.3e-52 176.3 0.0 5.8e-27 94.1 0.0 3.0 2 1 0 2 2 2 2 Nup85 Nucleoporin PGI PF00342.14 EIW66275.1 - 2e-211 702.6 0.0 2.6e-211 702.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase zf-AN1 PF01428.11 EIW66276.1 - 6e-19 67.6 30.8 9.5e-11 41.4 4.7 3.0 2 1 1 3 3 3 2 AN1-like Zinc finger SHOCT PF09851.4 EIW66276.1 - 0.1 12.1 0.6 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 Short C-terminal domain PhnA_Zn_Ribbon PF08274.7 EIW66276.1 - 0.56 10.0 9.4 2.6 7.9 0.0 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon IBR PF01485.16 EIW66276.1 - 3.7 7.4 24.1 3.8 7.4 9.2 3.1 1 1 1 2 2 2 0 IBR domain ERCC4 PF02732.10 EIW66277.1 - 2.2e-25 89.0 0.0 3.9e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HTH_45 PF14947.1 EIW66277.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix Sugar_tr PF00083.19 EIW66278.1 - 1.3e-88 297.5 25.0 1.6e-88 297.2 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW66278.1 - 4.8e-18 65.0 70.0 9.4e-15 54.1 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LIM PF00412.17 EIW66279.1 - 6.4e-17 61.3 17.4 1.7e-11 44.0 2.5 4.2 4 1 0 4 4 4 3 LIM domain zf-dskA_traR PF01258.12 EIW66279.1 - 3.4 7.4 7.2 0.97 9.2 1.0 3.1 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger WD40 PF00400.27 EIW66280.1 - 1.4e-49 164.2 22.7 3.8e-08 32.8 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW66280.1 - 3.4e-06 25.5 0.6 0.0022 16.2 0.1 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 VID27 PF08553.5 EIW66280.1 - 0.00098 17.4 0.0 0.0014 16.9 0.0 1.2 1 0 0 1 1 1 1 VID27 cytoplasmic protein PQQ_3 PF13570.1 EIW66280.1 - 0.0041 17.3 0.0 0.77 10.1 0.0 3.8 3 0 0 3 3 3 1 PQQ-like domain Drf_FH1 PF06346.7 EIW66280.1 - 0.059 12.8 0.5 0.096 12.1 0.3 1.2 1 0 0 1 1 1 0 Formin Homology Region 1 Nucleoporin_N PF08801.6 EIW66280.1 - 0.079 11.6 3.7 7.3 5.2 0.1 3.4 2 1 2 4 4 4 0 Nup133 N terminal like MFS_1 PF07690.11 EIW66281.1 - 1.8e-32 112.4 56.7 3.5e-26 91.7 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EIW66281.1 - 0.0012 17.1 5.9 0.0012 17.1 4.1 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector Abhydrolase_6 PF12697.2 EIW66282.1 - 3.2e-18 66.4 0.3 1.1e-16 61.4 0.2 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW66282.1 - 7.6e-09 35.4 0.0 1.4e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW66282.1 - 2.5e-08 33.7 0.0 5.3e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EIW66282.1 - 0.0018 17.9 0.3 0.0087 15.6 0.1 2.1 2 1 0 2 2 2 1 Serine hydrolase DUF1057 PF06342.7 EIW66282.1 - 0.0099 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF3716 PF12511.3 EIW66283.1 - 0.15 11.6 6.0 0.28 10.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Erp_C PF06780.6 EIW66284.1 - 0.02 14.7 0.2 0.031 14.1 0.2 1.2 1 0 0 1 1 1 0 Erp protein C-terminus BRCT PF00533.21 EIW66286.1 - 4.6e-10 39.4 0.0 2.4e-09 37.2 0.0 2.2 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EIW66286.1 - 0.0001 22.0 0.1 0.00041 20.1 0.1 2.1 1 1 0 1 1 1 1 twin BRCT domain Elf1 PF05129.8 EIW66287.1 - 3e-21 74.8 0.8 3e-21 74.8 0.6 2.4 3 0 0 3 3 3 1 Transcription elongation factor Elf1 like DDE_Tnp_1 PF01609.16 EIW66287.1 - 0.032 13.7 3.2 0.049 13.1 2.2 1.2 1 0 0 1 1 1 0 Transposase DDE domain zf-CHY PF05495.7 EIW66287.1 - 0.054 13.6 3.2 0.43 10.7 1.0 2.2 2 0 0 2 2 2 0 CHY zinc finger zf-3CxxC PF13695.1 EIW66287.1 - 0.07 13.3 3.1 0.045 13.9 0.7 1.8 2 0 0 2 2 2 0 Zinc-binding domain CDC45 PF02724.9 EIW66287.1 - 0.1 10.5 4.9 0.11 10.4 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Tcf25 PF04910.9 EIW66287.1 - 0.11 11.4 0.5 0.11 11.3 0.3 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 TFIIS_C PF01096.13 EIW66287.1 - 0.22 11.1 0.2 0.22 11.1 0.2 2.6 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 EIW66287.1 - 0.28 11.1 2.5 0.26 11.2 0.3 2.1 2 0 0 2 2 2 0 Zinc ribbon domain AAA PF00004.24 EIW66288.1 - 2.3e-45 153.9 0.0 6.5e-45 152.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIW66288.1 - 3.9e-09 36.6 0.0 7.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIW66288.1 - 8.8e-09 35.2 0.1 2.9e-08 33.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EIW66288.1 - 2e-07 30.1 0.0 3.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EIW66288.1 - 7.6e-07 29.2 0.5 9.8e-05 22.4 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EIW66288.1 - 8.7e-07 29.1 2.7 0.00013 22.1 0.3 3.5 2 1 1 3 3 3 1 AAA domain NTPase_1 PF03266.10 EIW66288.1 - 7.5e-05 22.5 0.2 0.00064 19.4 0.0 2.5 3 0 0 3 3 2 1 NTPase AAA_30 PF13604.1 EIW66288.1 - 0.00014 21.5 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIW66288.1 - 0.00017 21.2 0.0 0.0014 18.2 0.0 2.1 1 1 2 3 3 3 1 AAA domain AAA_28 PF13521.1 EIW66288.1 - 0.00028 20.8 0.1 0.001 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIW66288.1 - 0.00044 20.0 0.4 0.052 13.2 0.0 3.0 2 1 0 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 EIW66288.1 - 0.00045 19.9 0.1 0.0013 18.3 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EIW66288.1 - 0.00051 19.1 0.0 0.0012 17.9 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EIW66288.1 - 0.00052 19.9 0.0 0.0037 17.1 0.0 2.3 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EIW66288.1 - 0.0015 18.1 0.9 0.025 14.2 0.0 2.8 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.17 EIW66288.1 - 0.0023 18.0 0.0 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EIW66288.1 - 0.0038 18.0 0.2 0.012 16.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.6 EIW66288.1 - 0.0043 16.6 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIW66288.1 - 0.0045 16.8 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EIW66288.1 - 0.0049 15.6 0.0 0.0085 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus UPF0079 PF02367.12 EIW66288.1 - 0.0056 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EIW66288.1 - 0.0064 15.6 0.1 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AFG1_ATPase PF03969.11 EIW66288.1 - 0.0076 15.0 0.0 0.021 13.6 0.0 1.8 2 0 0 2 2 2 1 AFG1-like ATPase IstB_IS21 PF01695.12 EIW66288.1 - 0.0093 15.4 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 EIW66288.1 - 0.0093 15.5 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW66288.1 - 0.011 14.8 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EIW66288.1 - 0.019 14.4 2.9 0.071 12.5 0.1 2.5 2 1 1 3 3 2 0 AAA domain Sigma54_activat PF00158.21 EIW66288.1 - 0.026 14.0 0.2 0.63 9.4 0.0 2.7 3 1 0 3 3 3 0 Sigma-54 interaction domain AAA_18 PF13238.1 EIW66288.1 - 0.032 14.5 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain Bac_DnaA PF00308.13 EIW66288.1 - 0.046 13.3 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 EIW66288.1 - 0.05 12.7 0.2 0.71 8.9 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.1 EIW66288.1 - 0.053 13.8 0.1 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EIW66288.1 - 0.061 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 cobW PF02492.14 EIW66288.1 - 0.081 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CbiX PF01903.12 EIW66288.1 - 0.14 12.2 0.2 0.67 10.0 0.0 2.2 2 0 0 2 2 1 0 CbiX AAA_10 PF12846.2 EIW66288.1 - 0.15 11.4 1.0 0.57 9.5 0.1 2.5 2 1 0 2 2 2 0 AAA-like domain IncA PF04156.9 EIW66288.1 - 0.45 10.0 4.1 0.75 9.3 2.8 1.3 1 0 0 1 1 1 0 IncA protein RCC1 PF00415.13 EIW66289.1 - 1.2e-21 76.6 2.7 1.9e-05 24.8 0.0 5.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EIW66289.1 - 6.8e-19 67.9 0.0 3.2e-08 33.5 0.0 2.7 2 1 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.1 EIW66289.1 - 8.9e-11 41.6 0.3 1e-06 28.7 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW66289.1 - 3.7e-07 30.4 1.9 0.00014 22.2 0.1 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW66289.1 - 2.4e-06 27.2 0.2 0.057 13.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat RCC1_2 PF13540.1 EIW66289.1 - 4.2e-06 26.2 0.0 4.2e-06 26.2 0.0 4.7 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.25 EIW66289.1 - 5.1e-06 26.0 2.1 0.0027 17.4 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EIW66289.1 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF1479 PF07350.7 EIW66292.1 - 0.08 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AATase PF07247.7 EIW66292.1 - 0.23 9.9 0.1 0.42 9.0 0.0 1.4 1 1 0 1 1 1 0 Alcohol acetyltransferase EamA PF00892.15 EIW66293.1 - 1.5e-07 31.4 32.9 8.5e-05 22.6 6.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EIW66293.1 - 6.6e-07 29.0 7.9 6.6e-07 29.0 5.5 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 EIW66293.1 - 8.5e-05 22.7 5.7 8.5e-05 22.7 3.9 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter DUF4006 PF13179.1 EIW66293.1 - 0.24 10.9 6.0 6.5 6.3 0.6 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF4006) PAP2 PF01569.16 EIW66294.1 - 5.9e-17 61.5 3.0 5.9e-17 61.5 2.1 1.7 2 0 0 2 2 2 1 PAP2 superfamily Rhomboid PF01694.17 EIW66294.1 - 0.0089 16.0 4.2 0.085 12.8 0.1 2.2 2 0 0 2 2 2 2 Rhomboid family Epimerase PF01370.16 EIW66295.1 - 9.4e-18 64.5 0.0 1.2e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW66295.1 - 7.8e-09 34.6 0.0 1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW66295.1 - 2.4e-08 33.2 0.0 0.00047 19.1 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EIW66295.1 - 9.3e-07 28.9 0.0 2.3e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIW66295.1 - 6.4e-05 21.9 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EIW66295.1 - 0.04 13.9 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding Enterotoxin_a PF01375.12 EIW66295.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain KR PF08659.5 EIW66295.1 - 0.19 11.3 0.0 0.4 10.3 0.0 1.6 1 1 0 1 1 1 0 KR domain LacAB_rpiB PF02502.13 EIW66296.1 - 7.5e-42 142.2 0.3 8.4e-42 142.1 0.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4514 PF14986.1 EIW66296.1 - 0.1 12.3 0.9 0.45 10.3 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) Fungal_trans PF04082.13 EIW66297.1 - 1.2e-24 86.5 0.0 2.3e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW66297.1 - 6.1e-10 38.8 3.9 1.2e-09 37.9 2.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F_bP_aldolase PF01116.15 EIW66298.1 - 2.2e-69 233.7 0.0 2.5e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II TatD_DNase PF01026.16 EIW66298.1 - 0.095 11.8 0.0 0.27 10.3 0.0 1.8 3 0 0 3 3 3 0 TatD related DNase WEMBL PF05701.6 EIW66299.1 - 0.00093 17.7 18.8 0.0015 17.0 13.0 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light AAA_13 PF13166.1 EIW66299.1 - 0.018 13.5 12.9 0.027 12.9 8.9 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 EIW66299.1 - 0.02 15.0 0.7 0.02 15.0 0.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family THOC7 PF05615.8 EIW66299.1 - 0.049 13.8 16.4 0.85 9.8 6.4 2.5 1 1 0 2 2 2 0 Tho complex subunit 7 HOOK PF05622.7 EIW66299.1 - 0.08 10.7 16.7 0.13 10.0 11.6 1.2 1 0 0 1 1 1 0 HOOK protein CENP-F_leu_zip PF10473.4 EIW66299.1 - 0.12 12.2 20.5 0.65 9.8 10.8 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 EIW66299.1 - 0.29 10.9 31.9 0.14 11.9 5.2 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EIW66299.1 - 0.67 9.0 10.9 0.54 9.3 0.9 2.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 EIW66299.1 - 2.3 7.3 20.1 0.14 11.3 4.3 2.7 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 EIW66299.1 - 5.4 4.2 21.5 11 3.2 14.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 EIW66299.1 - 5.6 5.8 19.8 0.12 11.2 3.4 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HR1 PF02185.11 EIW66299.1 - 9.9 5.9 11.6 1.9 8.3 3.1 3.1 3 0 0 3 3 3 0 Hr1 repeat UCH PF00443.24 EIW66300.1 - 1.9e-21 76.4 0.0 3.1e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MULE PF10551.4 EIW66300.1 - 3.1e-08 33.6 0.0 1.3e-06 28.4 0.0 2.6 1 1 0 1 1 1 1 MULE transposase domain UCH_1 PF13423.1 EIW66300.1 - 2.5e-07 30.4 0.0 2.8e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YL1 PF05764.8 EIW66300.1 - 1.5 8.4 5.8 2.8 7.4 4.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein MFS_1 PF07690.11 EIW66301.1 - 6.7e-34 117.1 36.1 6.7e-34 117.1 25.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TPR_11 PF13414.1 EIW66302.1 - 5.4e-16 58.0 3.8 3.3e-08 33.0 0.4 2.6 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.1 EIW66302.1 - 3.7e-12 46.0 3.2 2.3e-07 30.6 0.2 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW66302.1 - 4e-12 45.0 8.2 7e-05 22.4 0.0 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW66302.1 - 9.3e-12 45.2 1.8 3.4e-05 24.3 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW66302.1 - 4.6e-11 42.9 2.0 7.5e-07 29.3 0.5 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW66302.1 - 5.6e-10 38.4 2.0 0.0029 17.1 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW66302.1 - 1.2e-09 37.6 0.4 0.024 14.7 0.0 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIW66302.1 - 2.1e-09 37.1 2.8 0.013 16.0 0.1 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW66302.1 - 3.3e-09 35.8 1.4 0.0074 16.0 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW66302.1 - 8.9e-07 28.2 1.6 0.0094 15.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW66302.1 - 1.3e-05 25.2 0.1 0.013 15.6 0.1 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIW66302.1 - 0.00058 20.1 6.6 3 8.4 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIW66302.1 - 0.019 14.8 0.8 1.5 8.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIW66302.1 - 0.022 15.1 0.3 0.93 10.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3808 PF10300.4 EIW66302.1 - 0.028 12.9 0.1 0.03 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Sel1 PF08238.7 EIW66302.1 - 0.039 14.5 0.6 0.095 13.3 0.1 1.9 2 0 0 2 2 2 0 Sel1 repeat Gene66 PF02053.10 EIW66303.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Gene 66 (IR5) protein Syntaxin_2 PF14523.1 EIW66303.1 - 0.071 13.1 2.8 2.2 8.3 0.3 3.3 2 1 1 3 3 2 0 Syntaxin-like protein Strumpellin PF10266.4 EIW66303.1 - 0.073 10.4 0.5 0.099 10.0 0.3 1.2 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin DUF904 PF06005.7 EIW66303.1 - 0.11 12.8 8.0 0.22 11.8 0.4 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF2203 PF09969.4 EIW66303.1 - 0.24 11.6 2.8 1.8 8.7 0.0 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.7 EIW66303.1 - 0.43 10.3 4.4 2.9 7.7 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 EIW66303.1 - 0.71 9.6 8.4 0.15 11.7 1.0 3.4 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Ly49 PF08391.5 EIW66303.1 - 1.4 9.0 3.2 24 5.0 0.2 2.8 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region TSC22 PF01166.13 EIW66303.1 - 1.5 8.8 8.5 12 5.9 0.1 3.7 3 1 1 4 4 4 0 TSC-22/dip/bun family FUSC PF04632.7 EIW66303.1 - 3.3 6.0 17.6 0.052 11.9 0.9 2.6 2 1 0 2 2 2 0 Fusaric acid resistance protein family IncA PF04156.9 EIW66303.1 - 4.7 6.7 14.7 1 8.9 5.9 2.8 2 2 0 2 2 2 0 IncA protein RR_TM4-6 PF06459.7 EIW66303.1 - 5.3 6.8 13.4 0.39 10.5 5.7 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 HALZ PF02183.13 EIW66303.1 - 6 6.6 7.2 2.8 7.7 0.8 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF972 PF06156.8 EIW66303.1 - 7.4 6.9 16.0 6.3 7.1 1.4 4.3 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 EIW66303.1 - 9.5 5.7 12.2 0.89 9.0 0.1 3.5 3 1 1 4 4 4 0 Septum formation initiator NUC153 PF08159.7 EIW66304.1 - 2.3e-12 46.2 0.8 4.3e-12 45.3 0.5 1.5 1 0 0 1 1 1 1 NUC153 domain Nop14 PF04147.7 EIW66304.1 - 2.6 5.8 20.8 0.0038 15.2 7.2 1.4 2 0 0 2 2 2 0 Nop14-like family Rhomboid PF01694.17 EIW66305.1 - 8.9e-22 77.6 11.9 8.9e-22 77.6 8.2 1.6 2 0 0 2 2 2 1 Rhomboid family Rad1 PF02144.11 EIW66309.1 - 2.4e-65 220.0 0.0 2.8e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 SUI1 PF01253.17 EIW66310.1 - 6.7e-27 93.1 0.3 1.3e-26 92.2 0.2 1.5 1 1 0 1 1 1 1 Translation initiation factor SUI1 rRNA_processing PF08524.6 EIW66311.1 - 3.3e-09 36.7 7.3 1.4e-06 28.1 0.1 3.1 3 0 0 3 3 3 2 rRNA processing MCM PF00493.18 EIW66313.1 - 8.3e-140 465.2 0.1 1.1e-139 464.9 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIW66313.1 - 3.2e-17 63.1 0.0 1e-16 61.5 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIW66313.1 - 2e-06 27.0 0.0 0.00045 19.4 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIW66313.1 - 5.3e-06 26.2 0.0 1.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIW66313.1 - 0.0008 19.0 0.1 0.0062 16.1 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW66313.1 - 0.022 14.2 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 EIW66313.1 - 0.028 14.7 0.4 0.2 12.0 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EIW66313.1 - 0.056 13.6 0.1 0.78 9.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sec5 PF15469.1 EIW66313.1 - 0.11 12.2 0.6 9.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec5 HSF_DNA-bind PF00447.12 EIW66315.1 - 7e-16 58.2 0.1 5.6e-13 48.9 0.0 2.5 2 0 0 2 2 2 2 HSF-type DNA-binding RRM_1 PF00076.17 EIW66316.1 - 7.9e-27 92.6 0.4 1.1e-15 56.9 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW66316.1 - 1.4e-22 79.4 0.1 8.4e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW66316.1 - 3.4e-08 33.2 0.1 0.0022 17.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0181 PF03701.9 EIW66316.1 - 0.13 11.5 5.0 0.14 11.4 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) OB_RNB PF08206.6 EIW66316.1 - 0.15 11.5 0.9 0.89 9.1 0.2 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain DHDPS PF00701.17 EIW66318.1 - 1e-42 145.7 0.0 1.3e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SET PF00856.23 EIW66319.1 - 0.02 15.2 0.0 0.066 13.5 0.0 1.9 1 1 0 1 1 1 0 SET domain Glutaredoxin PF00462.19 EIW66320.1 - 1.6e-10 40.8 0.1 5e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_9 PF14595.1 EIW66320.1 - 0.017 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF836 PF05768.9 EIW66320.1 - 0.028 14.6 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) TarH PF02203.10 EIW66320.1 - 0.031 14.1 0.1 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 Tar ligand binding domain homologue Thioredoxin_2 PF13098.1 EIW66320.1 - 0.033 14.4 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain LCM PF04072.9 EIW66324.1 - 1.7e-25 89.6 0.0 2.5e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase HA2 PF04408.18 EIW66325.1 - 3.1e-15 56.0 0.0 9.4e-15 54.4 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIW66325.1 - 1.5e-13 50.5 0.0 3.8e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIW66325.1 - 8.4e-11 41.5 0.4 2.4e-10 40.1 0.3 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW66325.1 - 1.3e-09 37.7 1.2 4.7e-09 35.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIW66325.1 - 0.00054 20.1 0.1 0.0016 18.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EIW66325.1 - 0.0015 18.3 0.0 0.04 13.7 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EIW66325.1 - 0.0053 15.6 0.0 0.015 14.2 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 EIW66325.1 - 0.0072 16.0 0.1 0.018 14.7 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EIW66325.1 - 0.0078 15.8 1.0 0.26 10.8 0.0 2.8 2 1 1 3 3 3 1 AAA domain RWD PF05773.17 EIW66325.1 - 0.0082 16.0 0.0 0.037 13.9 0.0 2.1 2 0 0 2 2 1 1 RWD domain SRP54 PF00448.17 EIW66325.1 - 0.017 14.5 0.1 0.26 10.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 EIW66325.1 - 0.018 14.7 0.0 0.067 12.8 0.0 2.0 2 0 0 2 2 1 0 Archaeal ATPase ABC_tran PF00005.22 EIW66325.1 - 0.031 14.5 0.1 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 EIW66325.1 - 0.038 13.4 0.0 0.091 12.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family KaiC PF06745.8 EIW66325.1 - 0.043 12.9 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.7 EIW66325.1 - 0.049 12.7 0.0 0.25 10.4 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin G-alpha PF00503.15 EIW66325.1 - 0.097 11.3 0.2 0.18 10.4 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit SHNi-TPR PF10516.4 EIW66326.1 - 6.1e-16 57.3 0.0 1.4e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_11 PF13414.1 EIW66326.1 - 3.5e-09 36.1 0.1 0.00034 20.2 0.0 2.9 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.1 EIW66326.1 - 3.2e-05 23.7 0.0 0.0035 17.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIW66326.1 - 3.6e-05 24.0 0.1 0.028 14.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW66326.1 - 0.00023 21.7 0.0 1.6 9.4 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat DrrA_P4M PF14860.1 EIW66326.1 - 0.0017 18.1 0.1 0.0043 16.8 0.1 1.6 1 0 0 1 1 1 1 DrrA phosphatidylinositol 4-phosphate binding domain TPR_2 PF07719.12 EIW66326.1 - 0.027 14.3 0.4 2.9 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Reo_sigmaC PF04582.7 EIW66326.1 - 0.12 11.5 2.4 3.2 6.8 0.6 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein OST3_OST6 PF04756.8 EIW66327.1 - 1.3e-21 76.8 3.6 1.8e-21 76.3 2.5 1.1 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EIW66327.1 - 0.0075 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Prp31_C PF09785.4 EIW66328.1 - 2.3e-41 141.0 3.1 5.7e-41 139.8 2.2 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EIW66328.1 - 1.3e-39 134.8 0.7 2.4e-39 134.0 0.5 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EIW66328.1 - 4.6e-18 64.7 0.2 9e-18 63.8 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain Alveol-reg_P311 PF11092.3 EIW66328.1 - 0.035 14.0 0.8 0.097 12.6 0.6 1.7 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) HTH_Tnp_Tc3_2 PF01498.13 EIW66331.1 - 4.6e-06 26.5 0.0 7.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Transposase SR-25 PF10500.4 EIW66332.1 - 0.0003 20.3 7.8 0.0005 19.6 5.4 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BUD22 PF09073.5 EIW66332.1 - 0.74 8.8 3.9 0.99 8.4 2.7 1.1 1 0 0 1 1 1 0 BUD22 AF-4 PF05110.8 EIW66332.1 - 2.5 5.8 15.8 3.6 5.3 11.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_S21 PF00716.12 EIW66332.1 - 3.5 6.8 6.9 5 6.3 4.8 1.2 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) zf-CCHC PF00098.18 EIW66333.1 - 0.00022 21.0 1.3 0.00036 20.3 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW66333.1 - 0.11 12.2 1.3 0.26 11.0 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW66333.1 - 0.28 11.4 6.5 0.08 13.1 2.4 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66333.1 - 1 7.9 2.8 1.3 7.5 2.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) RNA12 PF10443.4 EIW66338.1 - 2.2e-135 451.4 0.0 3.3e-135 450.9 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EIW66338.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 EIW66338.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 EIW66338.1 - 0.093 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_35 PF14516.1 EIW66338.1 - 0.099 11.2 0.0 0.29 9.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 EIW66338.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 mRNA_stabil PF13929.1 EIW66339.1 - 0.00078 18.4 0.0 0.0011 18.0 0.0 1.1 1 0 0 1 1 1 1 mRNA stabilisation PPR_3 PF13812.1 EIW66339.1 - 0.0057 16.8 0.2 0.38 11.1 0.1 2.3 2 0 0 2 2 2 1 Pentatricopeptide repeat domain TPR_16 PF13432.1 EIW66339.1 - 0.029 15.0 0.4 0.043 14.5 0.3 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF605 PF04652.11 EIW66339.1 - 0.82 8.9 9.8 0.97 8.7 6.8 1.0 1 0 0 1 1 1 0 Vta1 like Pex14_N PF04695.8 EIW66339.1 - 6.4 6.8 10.9 0.19 11.7 1.7 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 EIW66339.1 - 8.1 4.5 10.4 11 4.2 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Mpp10 PF04006.7 EIW66341.1 - 8.5e-94 315.0 56.5 8.5e-94 315.0 39.1 2.6 1 1 2 3 3 3 1 Mpp10 protein MFS_1 PF07690.11 EIW66342.1 - 8e-25 87.2 45.5 6.2e-23 81.0 30.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EIW66343.1 - 3.2e-26 91.8 51.2 1.6e-25 89.5 31.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EIW66344.1 - 1.4e-23 83.1 60.1 3.1e-22 78.7 37.4 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2290 PF10053.4 EIW66344.1 - 0.25 10.6 0.2 0.42 9.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2290) Rdx PF10262.4 EIW66345.1 - 2.7e-23 81.7 0.0 3.4e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Rdx family DUF2076 PF09849.4 EIW66346.1 - 5e-07 30.0 4.9 6.1e-07 29.7 3.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EIW66346.1 - 4.3e-05 23.3 0.8 5.9e-05 22.8 0.6 1.2 1 0 0 1 1 1 1 CHCH domain Rick_17kDa_Anti PF05433.10 EIW66346.1 - 0.084 12.5 4.1 0.15 11.7 2.9 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Methyltransf_23 PF13489.1 EIW66347.1 - 7.9e-22 77.6 0.0 1.7e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW66347.1 - 5.6e-18 65.2 0.0 9.3e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW66347.1 - 2.9e-17 62.6 0.0 4.6e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW66347.1 - 5.1e-14 52.8 0.1 7.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW66347.1 - 6e-13 49.1 0.0 1.1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIW66347.1 - 2.2e-09 36.7 0.0 3.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EIW66347.1 - 7.4e-09 34.7 0.0 1.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EIW66347.1 - 3.2e-08 33.8 0.0 8.1e-08 32.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 EIW66347.1 - 1.7e-05 24.0 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EIW66347.1 - 1.9e-05 23.9 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 EIW66347.1 - 6.6e-05 21.9 0.0 0.00015 20.7 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 EIW66347.1 - 0.00013 21.4 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 EIW66347.1 - 0.00019 20.8 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIW66347.1 - 0.00049 20.1 0.0 0.00079 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EIW66347.1 - 0.0064 15.8 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EIW66347.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EIW66347.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF605 PF04652.11 EIW66347.1 - 8 5.7 11.9 12 5.2 8.3 1.2 1 0 0 1 1 1 0 Vta1 like Glyco_tran_28_C PF04101.11 EIW66348.1 - 2.6e-26 92.2 0.0 2.9e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EIW66348.1 - 4e-08 32.8 0.0 4.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 Tn7_Tnp_TnsA_C PF08721.6 EIW66348.1 - 0.11 12.4 0.1 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 TnsA endonuclease C terminal Ribonuc_L-PSP PF01042.16 EIW66349.1 - 3.2e-42 143.1 0.1 3.6e-42 142.9 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Av_adeno_fibre PF06536.6 EIW66349.1 - 0.03 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Avian adenovirus fibre HAD_2 PF13419.1 EIW66350.1 - 1.7e-31 109.7 0.1 2.1e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW66350.1 - 0.0021 18.5 0.0 0.032 14.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW66350.1 - 0.074 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_6 PF13344.1 EIW66350.1 - 0.11 12.3 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Helitron_like_N PF14214.1 EIW66351.1 - 3.5e-19 69.2 0.0 7.3e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Sporozoite_P67 PF05642.6 EIW66353.1 - 0.046 11.5 4.4 0.045 11.6 3.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ADH_N PF08240.7 EIW66355.1 - 2.9e-28 97.8 1.9 6.2e-28 96.7 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW66355.1 - 4.6e-19 68.2 0.0 8e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EIW66355.1 - 0.0066 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EIW66355.1 - 0.014 15.0 0.1 0.07 12.7 0.0 1.9 1 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EIW66355.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3-HAO PF06052.7 EIW66356.1 - 6.4e-57 191.2 0.2 7.2e-57 191.0 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EIW66356.1 - 5.3e-08 32.2 0.0 9.1e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EIW66356.1 - 3.4e-05 23.2 0.0 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EIW66356.1 - 0.00022 20.9 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_4 PF08007.7 EIW66356.1 - 0.019 14.2 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Cupin superfamily protein ARD PF03079.9 EIW66356.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family UPF0113 PF03657.8 EIW66357.1 - 9.1e-09 35.1 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Proteasome PF00227.21 EIW66358.1 - 5.5e-49 166.0 0.1 6.7e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW66358.1 - 2.1e-13 49.2 1.3 3.8e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature YjgF_endoribonc PF14588.1 EIW66358.1 - 0.059 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Clat_adaptor_s PF01217.15 EIW66359.1 - 8.4e-10 38.5 0.0 2.7e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Clathrin adaptor complex small chain DDE_3 PF13358.1 EIW66362.1 - 5e-12 45.7 0.0 7.7e-11 41.9 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIW66362.1 - 1.9e-05 24.5 2.7 2.4e-05 24.2 0.7 2.1 2 0 0 2 2 2 1 Transposase TGF_beta_GS PF08515.7 EIW66364.1 - 0.058 12.7 0.8 0.26 10.6 0.5 2.2 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif UBN2_2 PF14227.1 EIW66365.1 - 7.5e-07 28.7 0.0 1.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EIW66365.1 - 1.4e-05 24.8 6.5 0.011 15.6 1.3 2.9 2 0 0 2 2 2 2 Zinc knuckle UBN2 PF14223.1 EIW66365.1 - 7.3e-05 22.5 0.7 0.00017 21.3 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type RVP PF00077.15 EIW66365.1 - 0.007 16.2 0.0 5.4 7.0 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease RVP_2 PF08284.6 EIW66365.1 - 0.008 16.1 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.1 EIW66365.1 - 0.0096 15.6 3.3 0.33 10.7 0.1 2.6 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.1 EIW66365.1 - 0.027 14.9 0.0 8 7.0 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease UBN2_3 PF14244.1 EIW66365.1 - 0.045 13.3 0.3 0.63 9.5 0.0 2.7 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type zf-CCHC_5 PF14787.1 EIW66365.1 - 0.88 9.1 6.9 5.6 6.5 0.6 2.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger SR-25 PF10500.4 EIW66366.1 - 0.98 8.8 31.6 0.11 11.9 9.4 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.6 EIW66367.1 - 0.32 11.0 1.2 0.42 10.6 0.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Tctex-1 PF03645.8 EIW66370.1 - 3.3e-07 30.0 0.1 3.6e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family PEX11 PF05648.9 EIW66371.1 - 7.3e-09 35.2 0.1 1.2e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Coatomer_WDAD PF04053.9 EIW66372.1 - 3.5e-151 503.9 0.0 6e-151 503.2 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 EIW66372.1 - 8.2e-52 171.3 14.0 7.2e-11 41.5 0.1 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW66372.1 - 0.025 12.7 0.0 6.5 4.7 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Ribosomal_L28e PF01778.12 EIW66373.1 - 4.7e-30 104.3 1.5 5.9e-30 104.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family ProRS-C_1 PF09180.6 EIW66374.1 - 1.4e-23 82.5 2.4 3.5e-23 81.3 1.7 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EIW66374.1 - 1.3e-21 76.9 0.0 2.3e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIW66374.1 - 8.7e-15 54.4 0.0 2.4e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.10 EIW66374.1 - 9.5e-08 31.9 0.1 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain zf-CCHC PF00098.18 EIW66378.1 - 0.00072 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF2587 PF10759.4 EIW66379.1 - 0.12 11.7 0.1 0.3 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Thaumatin PF00314.12 EIW66382.1 - 4.2e-58 196.3 11.2 5e-58 196.0 7.8 1.1 1 0 0 1 1 1 1 Thaumatin family Phosducin PF02114.11 EIW66383.1 - 1.4e-15 56.7 0.0 1.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Phosducin GOLD_2 PF13897.1 EIW66383.1 - 0.0075 16.5 0.3 0.012 15.8 0.0 1.4 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking Rubis-subs-bind PF09273.6 EIW66384.1 - 4.3e-08 33.1 0.0 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Velvet PF11754.3 EIW66386.1 - 7.9e-10 38.6 0.0 8.9e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 Velvet factor DCA16 PF15349.1 EIW66386.1 - 0.061 12.6 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 zf-CCHC PF00098.18 EIW66389.1 - 0.0022 17.8 1.9 0.0039 17.0 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW66389.1 - 0.048 13.3 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle MFS_1 PF07690.11 EIW66391.1 - 3.6e-24 85.1 37.1 6.3e-16 58.0 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW66391.1 - 0.035 12.6 25.1 0.083 11.4 3.5 3.9 2 2 0 3 3 3 0 Sugar (and other) transporter Thaumatin PF00314.12 EIW66392.1 - 7.4e-58 195.4 4.1 8.4e-58 195.3 2.8 1.0 1 0 0 1 1 1 1 Thaumatin family Aft1_HRA PF11786.3 EIW66393.1 - 6.4e-21 74.3 11.9 6.4e-21 74.3 8.2 2.5 3 0 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.16 EIW66393.1 - 3.9e-12 45.9 3.4 6.2e-12 45.2 2.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 EIW66393.1 - 1.7e-06 28.4 3.7 1.7e-06 28.4 2.6 3.2 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EIW66393.1 - 2.5e-06 27.2 4.7 4.4e-06 26.4 3.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIW66393.1 - 0.0055 16.9 2.9 0.011 16.0 2.0 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor HALZ PF02183.13 EIW66393.1 - 0.0075 15.9 0.1 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper adh_short PF00106.20 EIW66394.1 - 2.8e-61 206.2 8.7 1.6e-31 109.5 1.2 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EIW66394.1 - 9.9e-30 102.4 0.0 2.1e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EIW66394.1 - 3.1e-28 98.6 5.3 4.9e-15 55.6 0.4 2.4 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EIW66394.1 - 9.3e-18 64.8 0.8 8.9e-09 35.4 0.1 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 EIW66394.1 - 1.2e-11 44.5 0.0 2.3e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase FRD2 PF03197.8 EIW66394.1 - 0.0012 19.4 2.3 0.094 13.2 0.0 2.8 3 0 0 3 3 3 1 Bacteriophage FRD2 protein DUF1659 PF07872.6 EIW66394.1 - 0.0061 16.1 0.0 4.8 6.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1659) THF_DHG_CYH_C PF02882.14 EIW66394.1 - 0.1 11.6 4.5 2.9 6.9 0.1 2.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Phage_holin_1 PF04531.8 EIW66394.1 - 0.14 12.2 0.1 5.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage holin 3HCDH_N PF02737.13 EIW66394.1 - 0.3 10.7 10.1 2.3 7.8 0.8 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.7 EIW66394.1 - 0.39 10.6 3.5 5 7.1 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Glyco_hydro_47 PF01532.15 EIW66396.1 - 7.7e-32 110.5 0.0 1.1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MutS_III PF05192.13 EIW66397.1 - 0.001 18.8 1.7 0.0021 17.8 1.2 1.4 1 0 0 1 1 1 1 MutS domain III TPR_MLP1_2 PF07926.7 EIW66397.1 - 0.019 14.7 13.3 0.036 13.7 1.5 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMCO5 PF14992.1 EIW66397.1 - 0.11 11.6 10.6 0.3 10.1 7.4 1.7 1 0 0 1 1 1 0 TMCO5 family Seryl_tRNA_N PF02403.17 EIW66397.1 - 0.81 9.7 11.0 0.45 10.5 5.4 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain MULE PF10551.4 EIW66398.1 - 0.011 15.9 0.0 0.046 13.8 0.0 2.1 1 0 0 1 1 1 0 MULE transposase domain Zn_clus PF00172.13 EIW66399.1 - 2.7 7.9 15.4 0.51 10.2 2.5 2.7 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCHC PF00098.18 EIW66400.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66400.1 - 0.35 11.1 8.0 0.092 12.9 3.4 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66400.1 - 0.63 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) IL2 PF00715.12 EIW66401.1 - 0.014 15.0 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 Interleukin 2 MFS_1 PF07690.11 EIW66403.1 - 1.7e-34 119.1 51.0 1.7e-34 119.1 35.3 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW66403.1 - 1.9e-07 29.6 12.7 1.9e-07 29.6 8.8 2.3 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF360 PF04020.8 EIW66403.1 - 4.5 7.6 12.2 0.15 12.4 1.6 3.3 3 1 0 3 3 3 0 Membrane protein of unknown function FixQ PF05545.6 EIW66403.1 - 6.7 6.4 10.5 6.2 6.5 0.1 3.6 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF3824 PF12868.2 EIW66405.1 - 3.4 8.6 7.2 8.9 7.2 5.0 1.7 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) HMG_CoA_synt_C PF08540.5 EIW66406.1 - 1.1e-79 267.9 0.0 3.3e-59 200.6 0.0 2.1 2 0 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EIW66406.1 - 3.2e-79 264.5 0.4 6.4e-79 263.5 0.1 1.7 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.5 EIW66406.1 - 5.4e-06 26.3 0.2 1.7e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal TGT_C2 PF14810.1 EIW66406.1 - 0.021 14.6 0.1 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase PTS_2-RNA PF01885.11 EIW66407.1 - 2.9e-60 202.7 0.0 3.5e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family IPK PF03770.11 EIW66408.1 - 1.6e-39 135.6 0.0 1.8e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase PAS_10 PF13596.1 EIW66409.1 - 1.2 9.4 7.0 3.9 7.7 0.7 3.2 2 1 1 3 3 3 0 PAS domain SBDS PF01172.13 EIW66411.1 - 2.3e-12 46.5 0.0 2.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein adh_short PF00106.20 EIW66412.1 - 1.5e-07 31.4 0.1 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EIW66412.1 - 0.0026 17.8 0.1 0.0046 16.9 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIW66412.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 KR domain Ins145_P3_rec PF08709.6 EIW66413.1 - 0.062 12.3 0.2 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Zn_clus PF00172.13 EIW66414.1 - 2.2e-12 46.6 25.7 1.4e-06 28.0 7.2 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain cwf21 PF08312.7 EIW66415.1 - 4.2e-14 52.1 5.0 4.2e-14 52.1 3.4 2.3 2 1 0 2 2 2 1 cwf21 domain AMMECR1 PF01871.12 EIW66416.1 - 5e-36 123.4 0.0 1.2e-34 118.9 0.0 2.0 1 1 0 1 1 1 1 AMMECR1 Tim54 PF11711.3 EIW66418.1 - 0.074 11.6 1.7 0.083 11.4 1.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4526 PF15029.1 EIW66418.1 - 0.66 9.4 3.3 0.77 9.2 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4526) CD99L2 PF12301.3 EIW66422.1 - 0.13 11.9 3.7 0.26 10.9 2.6 1.7 1 1 0 1 1 1 0 CD99 antigen like protein 2 Methyltransf_31 PF13847.1 EIW66423.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Vps39_1 PF10366.4 EIW66424.1 - 1.9e-30 105.0 1.3 5.3e-30 103.6 0.1 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EIW66424.1 - 3.8e-28 97.8 0.4 8.2e-28 96.7 0.3 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EIW66424.1 - 1.8e-11 43.7 3.8 1.9e-09 37.2 0.4 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.17 EIW66424.1 - 4.8e-08 32.7 0.0 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 2 CNH domain Cation_efflux PF01545.16 EIW66425.1 - 7e-46 156.5 13.0 2.3e-32 112.2 3.0 2.8 2 1 0 2 2 2 2 Cation efflux family Choline_transpo PF04515.7 EIW66426.1 - 1.5e-11 43.6 19.1 2e-09 36.6 1.1 2.3 2 0 0 2 2 2 2 Plasma-membrane choline transporter DUF4064 PF13273.1 EIW66426.1 - 1.1 9.4 7.7 0.51 10.4 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) TadE PF07811.7 EIW66426.1 - 8.8 6.3 9.7 1.3 8.9 0.1 3.5 3 0 0 3 3 3 0 TadE-like protein WD40 PF00400.27 EIW66428.1 - 2.7e-54 179.1 16.4 2.3e-10 39.9 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EIW66428.1 - 6.1e-30 104.1 0.0 1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EIW66428.1 - 0.0059 14.8 2.1 0.11 10.6 0.0 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW66428.1 - 0.14 11.8 0.0 46 3.6 0.0 3.1 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF3299 PF11736.3 EIW66429.1 - 0.13 12.1 0.5 0.2 11.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) Rpr2 PF04032.11 EIW66430.1 - 2.3e-09 36.9 0.1 9e-09 35.0 0.0 2.1 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Vac_ImportDeg PF09783.4 EIW66431.1 - 2.1e-47 160.8 0.0 3.3e-45 153.7 0.0 2.1 2 0 0 2 2 2 2 Vacuolar import and degradation protein Asn_synthase PF00733.16 EIW66432.1 - 1.6e-71 240.8 0.0 2.2e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EIW66432.1 - 3.5e-37 126.9 0.0 5.9e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EIW66432.1 - 6.1e-30 103.8 0.0 1.6e-29 102.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EIW66432.1 - 6.7e-05 22.1 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EIW66432.1 - 0.001 17.8 0.0 0.057 12.1 0.0 2.6 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EIW66432.1 - 0.028 13.3 0.0 0.083 11.7 0.0 1.7 2 0 0 2 2 2 0 NAD synthase SSP160 PF06933.6 EIW66433.1 - 0.053 11.5 3.5 0.1 10.5 2.4 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-C2H2 PF00096.21 EIW66434.1 - 1.3e-09 37.7 7.8 3.3e-05 23.9 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW66434.1 - 1.2e-07 31.5 7.6 0.0014 18.7 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW66434.1 - 7.6e-07 29.1 7.4 2.8e-06 27.3 2.3 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIW66434.1 - 0.029 14.2 0.5 0.23 11.3 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger RhoGEF PF00621.15 EIW66436.1 - 3.3e-12 46.6 0.1 6.4e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain SPATIAL PF15256.1 EIW66438.1 - 0.031 14.3 0.2 0.053 13.5 0.1 1.3 1 0 0 1 1 1 0 SPATIAL SOG2 PF10428.4 EIW66438.1 - 0.14 10.8 2.1 0.16 10.6 1.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Pox_Ag35 PF03286.9 EIW66438.1 - 4.6 6.7 9.6 0.37 10.2 3.6 1.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PCI PF01399.22 EIW66439.1 - 0.0014 18.8 0.0 0.0038 17.5 0.0 1.7 1 1 0 1 1 1 1 PCI domain Anemone_cytotox PF06369.7 EIW66439.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein HTH_Tnp_Tc5 PF03221.11 EIW66440.1 - 0.02 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DUF3752 PF12572.3 EIW66442.1 - 0.073 13.1 1.7 0.079 13.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) RabGAP-TBC PF00566.13 EIW66443.1 - 3.2e-38 131.3 0.1 4.3e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FXR1P_C PF12235.3 EIW66443.1 - 0.0075 16.3 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Fragile X-related 1 protein C terminal Med21 PF11221.3 EIW66444.1 - 1.4e-14 54.3 6.8 3e-14 53.2 4.7 1.5 1 0 0 1 1 1 1 Subunit 21 of Mediator complex AAA PF00004.24 EIW66444.1 - 6.2e-14 52.3 0.0 1.3e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EIW66444.1 - 7.9e-12 45.1 0.0 3.1e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EIW66444.1 - 1.5e-10 40.9 0.0 4.9e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EIW66444.1 - 1e-08 34.3 0.0 1e-06 27.7 0.0 2.2 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EIW66444.1 - 3.6e-07 30.3 0.0 2.3e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW66444.1 - 6.2e-06 25.8 0.1 4.4e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EIW66444.1 - 2.8e-05 24.2 2.6 0.00084 19.3 0.0 3.5 3 2 1 4 4 4 1 AAA ATPase domain AAA_11 PF13086.1 EIW66444.1 - 4.4e-05 23.1 0.1 0.00012 21.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIW66444.1 - 6e-05 22.1 0.0 0.00023 20.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EIW66444.1 - 0.00058 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIW66444.1 - 0.00063 19.3 0.0 0.004 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIW66444.1 - 0.00076 18.6 0.0 0.0066 15.6 0.0 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EIW66444.1 - 0.0037 16.8 0.0 0.0074 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EIW66444.1 - 0.0046 17.3 0.1 0.47 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIW66444.1 - 0.013 14.9 0.1 0.055 12.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EIW66444.1 - 0.015 14.2 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EIW66444.1 - 0.03 14.3 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EIW66444.1 - 0.03 13.7 0.4 0.3 10.4 0.0 2.3 2 1 0 3 3 3 0 AAA-like domain AAA_5 PF07728.9 EIW66444.1 - 0.031 13.9 0.1 0.16 11.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EIW66444.1 - 0.043 12.7 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.24 EIW66444.1 - 0.043 13.3 0.1 0.42 10.0 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_17 PF13207.1 EIW66444.1 - 0.08 13.7 0.0 0.2 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW66444.1 - 0.21 11.0 1.1 0.62 9.4 0.0 2.3 2 1 1 3 3 3 0 FtsK/SpoIIIE family Syntaxin PF00804.20 EIW66444.1 - 2.3 8.4 5.8 12 6.1 3.2 2.6 2 1 0 2 2 1 0 Syntaxin AAA_13 PF13166.1 EIW66444.1 - 6.8 5.0 5.7 12 4.1 2.1 2.2 3 0 0 3 3 3 0 AAA domain zf-CCHC PF00098.18 EIW66446.1 - 0.0031 17.3 0.1 0.006 16.4 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Clathrin_lg_ch PF01086.12 EIW66453.1 - 0.017 15.0 0.2 0.025 14.4 0.1 1.2 1 0 0 1 1 1 0 Clathrin light chain PSK PF06404.7 EIW66453.1 - 0.028 15.1 0.7 0.21 12.3 0.0 2.3 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) CMS1 PF14617.1 EIW66455.1 - 7.4e-39 133.3 1.1 3.8e-37 127.7 0.8 2.1 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EIW66455.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase Pap_E4 PF02711.9 EIW66455.1 - 0.73 10.6 7.7 1.3 9.9 2.0 2.3 2 0 0 2 2 2 0 E4 protein Glyco_hydro_9 PF00759.14 EIW66456.1 - 2.8e-86 290.1 12.9 1.8e-85 287.5 8.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 Adeno_E3_CR2 PF02439.10 EIW66456.1 - 4.3 6.9 4.9 7.1 6.2 3.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 KAT11 PF08214.6 EIW66457.1 - 2.8e-27 95.7 5.2 1.2e-25 90.3 3.7 2.6 1 1 0 1 1 1 1 Histone acetylation protein zf-C2H2 PF00096.21 EIW66458.1 - 6.9e-09 35.5 16.3 4.4e-06 26.7 1.2 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW66458.1 - 2.6e-06 27.4 4.9 2.6e-06 27.4 3.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EIW66458.1 - 0.00025 21.1 5.7 0.00046 20.2 0.1 3.1 3 1 1 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EIW66458.1 - 0.00064 19.8 0.8 0.00064 19.8 0.6 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW66458.1 - 0.0073 16.4 0.0 0.0073 16.4 0.0 2.3 3 0 0 3 3 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIW66458.1 - 0.031 14.1 0.1 0.031 14.1 0.1 2.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3505 PF12013.3 EIW66458.1 - 0.24 11.6 0.1 0.24 11.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3505) zf-UBP PF02148.14 EIW66458.1 - 0.32 11.1 10.1 1.3 9.2 7.0 2.0 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-HIT PF04438.11 EIW66458.1 - 2.7 7.7 8.7 8 6.2 0.4 2.7 3 0 0 3 3 3 0 HIT zinc finger zf-C2H2_2 PF12756.2 EIW66458.1 - 3.9 7.6 7.7 2e+02 2.1 5.3 2.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 EIW66458.1 - 4.5 7.7 10.0 0.76 10.1 3.6 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger zf-H2C2_5 PF13909.1 EIW66458.1 - 6.5 7.2 11.7 9.4 6.7 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain C1_2 PF03107.11 EIW66458.1 - 7.8 6.7 7.2 34 4.6 0.1 2.6 2 0 0 2 2 2 0 C1 domain zf-CCHC PF00098.18 EIW66460.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66460.1 - 0.33 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66460.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) SR-25 PF10500.4 EIW66461.1 - 0.51 9.7 27.7 0.049 13.1 8.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.18 EIW66463.1 - 0.00021 21.0 1.3 0.00036 20.3 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW66463.1 - 0.11 12.2 1.3 0.26 11.0 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW66463.1 - 0.36 11.0 7.4 0.097 12.9 3.0 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66463.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DDE_3 PF13358.1 EIW66465.1 - 2.6e-11 43.4 0.2 5.2e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.1 EIW66465.1 - 8.3e-05 22.0 1.2 0.00022 20.6 0.8 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EIW66465.1 - 0.00015 21.7 1.0 0.00041 20.3 0.1 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIW66465.1 - 0.00042 20.4 0.9 0.0011 19.0 0.1 2.1 2 1 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIW66465.1 - 0.0071 15.9 1.4 0.23 11.1 0.1 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.1 EIW66465.1 - 0.085 12.2 0.3 5.4 6.4 0.1 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding SAC3_GANP PF03399.11 EIW66468.1 - 0.0023 17.5 0.1 0.0044 16.6 0.1 1.5 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SKIP_SNW PF02731.10 EIW66469.1 - 1e-67 226.5 4.5 1e-67 226.5 3.1 2.6 2 0 0 2 2 2 1 SKIP/SNW domain Nucleoplasmin PF03066.10 EIW66469.1 - 0.15 11.6 6.7 0.29 10.6 4.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EIW66469.1 - 0.23 9.4 7.8 0.37 8.7 5.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Adeno_E1B_55K_N PF04623.7 EIW66469.1 - 4.8 7.7 7.6 0.24 11.9 0.2 2.5 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus TRAP_alpha PF03896.11 EIW66469.1 - 6.3 5.7 8.5 12 4.7 5.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit XAP5 PF04921.9 EIW66469.1 - 9.8 5.6 13.0 3.4 7.1 4.8 2.5 2 0 0 2 2 2 0 XAP5, circadian clock regulator DAO PF01266.19 EIW66472.1 - 6e-40 137.2 0.0 8.4e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW66472.1 - 0.00024 21.0 0.6 0.00049 20.0 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW66472.1 - 0.00036 20.6 0.3 0.0081 16.2 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW66472.1 - 0.022 15.1 0.6 0.022 15.1 0.4 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW66472.1 - 0.048 13.5 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BssS PF13991.1 EIW66472.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 BssS protein family Peptidase_S8 PF00082.17 EIW66475.1 - 6.8e-49 166.5 0.1 1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EIW66475.1 - 5.3e-29 99.8 0.2 1.3e-28 98.6 0.1 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain UNC45-central PF11701.3 EIW66476.1 - 3.8e-14 52.6 0.0 1.5e-13 50.7 0.0 2.1 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Arm PF00514.18 EIW66476.1 - 0.0033 17.2 7.2 0.088 12.6 0.1 4.1 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Phage_holin_T PF11031.3 EIW66476.1 - 0.062 12.4 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage T holin SET PF00856.23 EIW66477.1 - 5e-21 75.6 0.0 9.5e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.11 EIW66477.1 - 6.9e-08 32.7 2.2 6.9e-08 32.7 1.5 2.2 2 0 0 2 2 2 1 Pre-SET motif FlgD_ig PF13860.1 EIW66478.1 - 0.033 13.9 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 FlgD Ig-like domain CDC27 PF09507.5 EIW66478.1 - 0.091 11.9 8.8 0.12 11.6 6.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF566 PF04484.7 EIW66478.1 - 4.9 6.5 15.2 6.2 6.2 10.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Rib_recp_KP_reg PF05104.7 EIW66478.1 - 8 6.9 10.3 16 6.0 7.1 1.5 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Gpi1 PF05024.10 EIW66479.1 - 2e-41 141.7 0.7 3.1e-41 141.1 0.5 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MFS_1 PF07690.11 EIW66480.1 - 7.1e-29 100.6 46.2 7.1e-29 100.6 32.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW66480.1 - 1.7e-08 33.1 8.2 2.3e-08 32.7 5.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HEAT_2 PF13646.1 EIW66481.1 - 0.014 15.6 0.3 0.27 11.5 0.0 3.2 4 0 0 4 4 4 0 HEAT repeats Arm PF00514.18 EIW66481.1 - 0.14 12.0 4.5 0.3 10.9 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Peptidase_A22B PF04258.8 EIW66482.1 - 8.7e-61 205.9 4.8 1.1e-60 205.6 3.3 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EIW66482.1 - 0.029 13.4 11.1 0.53 9.3 7.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1119) CR6_interact PF10147.4 EIW66483.1 - 0.00072 18.9 1.9 0.0026 17.1 0.0 2.1 2 0 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Auxin_repressed PF05564.7 EIW66483.1 - 1 9.9 10.6 1.6 9.3 1.0 3.3 1 1 2 3 3 3 0 Dormancy/auxin associated protein SMC_Nse1 PF07574.8 EIW66484.1 - 1.2e-20 73.9 0.0 3.1e-13 49.7 0.0 2.3 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EIW66484.1 - 1.2e-06 28.4 8.1 2.1e-06 27.5 5.6 1.5 1 0 0 1 1 1 1 RING-like domain zf-RING_4 PF14570.1 EIW66484.1 - 0.059 12.9 5.8 0.11 12.0 4.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EIW66484.1 - 0.25 11.3 5.5 0.91 9.5 3.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.1 EIW66484.1 - 0.36 10.6 10.4 0.64 9.8 7.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-P11 PF03854.9 EIW66484.1 - 0.82 9.1 6.9 8.7 5.9 4.8 2.2 1 1 0 1 1 1 0 P-11 zinc finger PHD PF00628.24 EIW66484.1 - 4.9 6.9 7.5 12 5.6 5.2 1.7 1 0 0 1 1 1 0 PHD-finger Mnd1 PF03962.10 EIW66487.1 - 4.8e-52 176.3 0.2 6e-52 176.0 0.1 1.0 1 0 0 1 1 1 1 Mnd1 family Allexi_40kDa PF05549.6 EIW66487.1 - 0.0063 15.8 0.1 0.0099 15.2 0.1 1.3 1 0 0 1 1 1 1 Allexivirus 40kDa protein COG2 PF06148.6 EIW66487.1 - 0.058 13.2 0.7 0.13 12.0 0.5 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TFR_dimer PF04253.10 EIW66487.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain Tropomyosin_1 PF12718.2 EIW66487.1 - 0.6 9.9 8.1 0.28 11.0 4.0 1.6 2 0 0 2 2 2 0 Tropomyosin like Pribosyltran_N PF13793.1 EIW66488.1 - 2.2e-43 146.7 0.0 5e-43 145.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EIW66488.1 - 1.1e-38 132.8 0.0 1.7e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EIW66488.1 - 1.7e-14 53.5 0.2 1.5e-13 50.5 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIW66488.1 - 0.00083 18.6 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF4072 PF13284.1 EIW66488.1 - 0.37 11.0 4.6 9.4 6.5 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4072) eIF2A PF08662.6 EIW66489.1 - 1.7e-73 246.5 0.0 3.4e-73 245.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A 4F5 PF04419.9 EIW66490.1 - 1.1e-06 29.2 12.6 1.1e-06 29.2 8.8 2.1 2 0 0 2 2 2 1 4F5 protein family Taxilin PF09728.4 EIW66491.1 - 0.21 10.6 0.4 0.27 10.2 0.3 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF2931 PF11153.3 EIW66492.1 - 0.033 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) SelP_N PF04592.9 EIW66495.1 - 8.3 5.7 10.5 17 4.6 7.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HlyIII PF03006.15 EIW66496.1 - 1.2e-50 172.0 16.9 1.4e-50 171.7 11.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DEAD PF00270.24 EIW66497.1 - 1.2e-40 138.7 0.0 2e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW66497.1 - 1.1e-25 89.2 0.0 1.2e-24 85.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW66497.1 - 0.00027 20.8 0.0 0.00069 19.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW66497.1 - 0.0012 19.0 0.0 0.0039 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Trigger_C PF05698.9 EIW66497.1 - 0.023 14.5 1.1 5.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus DUF1253 PF06862.7 EIW66497.1 - 0.037 12.4 0.0 1.4 7.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) zf-C2H2 PF00096.21 EIW66498.1 - 3.5e-10 39.6 5.0 0.0012 19.0 0.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW66498.1 - 2.4e-08 33.8 6.3 0.00054 20.1 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW66498.1 - 7.7e-06 25.8 4.2 0.12 12.8 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW66498.1 - 0.37 10.9 3.4 1.5 9.0 0.1 3.2 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ZF-HD_dimer PF04770.7 EIW66498.1 - 0.79 9.8 5.9 4.3 7.4 0.3 2.3 1 1 1 2 2 2 0 ZF-HD protein dimerisation region Pkinase PF00069.20 EIW66499.1 - 6.4e-73 245.1 0.0 7.8e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW66499.1 - 6.2e-37 127.0 0.0 8.8e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW66499.1 - 5.6e-05 22.2 0.0 0.00013 21.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 EIW66499.1 - 0.043 13.1 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EIW66499.1 - 0.1 11.6 1.1 0.32 10.0 0.8 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MTBP_mid PF14919.1 EIW66500.1 - 0.0089 14.7 1.4 0.013 14.1 1.0 1.2 1 0 0 1 1 1 1 MDM2-binding DUF2361 PF10153.4 EIW66500.1 - 3.7 7.7 8.7 0.88 9.7 2.7 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2361) SYF2 PF08231.7 EIW66501.1 - 8e-44 149.4 9.7 8e-44 149.4 6.7 1.5 2 0 0 2 2 2 1 SYF2 splicing factor DUF413 PF04219.7 EIW66501.1 - 0.017 14.8 0.9 0.035 13.8 0.1 1.9 3 0 0 3 3 3 0 Protein of unknown function, DUF Ig_J_chain PF15097.1 EIW66501.1 - 0.043 13.3 0.4 0.83 9.2 0.4 2.5 1 1 2 3 3 3 0 Immunoglobulin J chain Ribosomal_S30AE PF02482.14 EIW66501.1 - 0.053 13.9 4.6 0.093 13.1 0.5 3.0 2 1 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF2563 PF10817.3 EIW66501.1 - 0.11 12.9 1.1 0.34 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2563) 2OG-FeII_Oxy_2 PF13532.1 EIW66506.1 - 1.3e-19 70.8 0.0 2.4e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW66506.1 - 0.00037 20.7 0.0 0.00085 19.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Git3 PF11710.3 EIW66507.1 - 3.5e-11 43.0 5.3 6.4e-11 42.2 3.6 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EIW66507.1 - 1.3e-05 24.4 5.4 5.1e-05 22.5 3.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Anp1 PF03452.9 EIW66508.1 - 0.03 13.4 0.3 0.041 13.0 0.2 1.1 1 0 0 1 1 1 0 Anp1 Ribosomal_S30AE PF02482.14 EIW66508.1 - 0.1 13.0 4.3 0.084 13.3 0.8 1.9 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein 3Beta_HSD PF01073.14 EIW66511.1 - 4.3e-10 38.7 0.0 3.9e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIW66511.1 - 6.6e-10 38.8 0.0 1.4e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIW66511.1 - 8.4e-09 34.7 0.6 2.9e-08 32.9 0.4 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EIW66511.1 - 4.8e-07 29.9 0.3 7e-05 22.9 0.2 2.5 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EIW66511.1 - 0.052 13.1 0.2 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 EIW66511.1 - 0.062 13.2 0.1 1.3 8.9 0.1 2.5 1 1 0 1 1 1 0 short chain dehydrogenase Acatn PF13000.2 EIW66512.1 - 4.9e-153 510.5 9.3 5.2e-78 262.9 0.1 2.5 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 PMM PF03332.8 EIW66513.1 - 6.5e-107 356.1 0.2 7.7e-107 355.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EIW66513.1 - 0.0053 16.3 0.0 0.021 14.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase COG6 PF06419.6 EIW66514.1 - 1.5e-168 561.7 0.0 1.7e-168 561.5 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 EzrA PF06160.7 EIW66514.1 - 0.012 13.8 0.2 0.025 12.8 0.0 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CDP-OH_P_transf PF01066.16 EIW66515.1 - 1e-17 64.2 8.2 2.5e-17 63.0 5.7 1.8 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Gly_transf_sug PF04488.10 EIW66516.1 - 7.4e-17 61.6 0.1 2.2e-16 60.0 0.1 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EIW66516.1 - 0.00085 17.9 2.3 0.42 9.0 0.1 2.4 2 1 1 3 3 3 2 TcdA/TcdB catalytic glycosyltransferase domain DPBB_1 PF03330.13 EIW66519.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Mucin PF01456.12 EIW66519.1 - 0.33 10.7 30.8 0.021 14.6 16.0 2.0 1 1 1 2 2 2 0 Mucin-like glycoprotein zf-H2C2_2 PF13465.1 EIW66520.1 - 1.2e-21 75.8 53.4 6.7e-09 35.6 2.8 8.5 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2 PF00096.21 EIW66520.1 - 5.1e-21 73.6 49.4 6.2e-06 26.2 0.9 9.2 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW66520.1 - 8.8e-10 38.2 56.9 0.00011 22.3 0.7 9.1 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW66520.1 - 0.0037 17.3 0.1 0.0037 17.3 0.1 6.6 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIW66520.1 - 0.004 16.9 13.5 0.79 9.7 0.0 5.8 6 0 0 6 6 6 2 C2H2-type zinc finger MFS_1 PF07690.11 EIW66522.1 - 6.2e-34 117.2 47.4 6.2e-34 117.2 32.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW66522.1 - 3e-07 29.4 12.6 3e-07 29.4 8.7 3.4 2 1 0 3 3 3 1 Sugar (and other) transporter CENP-C_C PF11699.3 EIW66523.1 - 9.4e-29 99.2 1.2 1.5e-28 98.6 0.8 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EIW66523.1 - 3.2e-05 23.3 0.0 7.9e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 Cupin domain HECT PF00632.20 EIW66524.1 - 2.3e-90 303.0 0.0 3e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EIW66524.1 - 3.8e-33 112.9 17.2 2.1e-11 43.4 1.4 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EIW66524.1 - 4.2e-15 55.3 0.1 1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain YsaB PF13983.1 EIW66524.1 - 0.087 12.9 0.0 22 5.2 0.0 2.5 2 0 0 2 2 2 0 YsaB-like lipoprotein DUF2157 PF09925.4 EIW66525.1 - 0.017 14.7 0.1 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) zf-met PF12874.2 EIW66526.1 - 3e-07 30.4 0.2 5.1e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW66526.1 - 3.6e-06 26.9 0.1 6.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1777 PF08648.7 EIW66526.1 - 0.0033 17.2 13.8 0.0033 17.2 9.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-U1 PF06220.7 EIW66526.1 - 0.019 14.5 0.2 0.035 13.6 0.2 1.4 1 0 0 1 1 1 0 U1 zinc finger Nucleoporin_C PF03177.9 EIW66527.1 - 2.2e-49 168.4 1.3 3.4e-49 167.8 0.9 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EIW66527.1 - 3.5e-13 49.0 0.0 4.1e-12 45.5 0.0 2.1 1 1 0 1 1 1 1 Nup133 N terminal like PAXNEB PF05625.6 EIW66528.1 - 2.2e-45 155.1 0.0 2.2e-44 151.7 0.0 2.0 1 1 0 1 1 1 1 PAXNEB protein KaiC PF06745.8 EIW66528.1 - 7.8e-05 21.8 0.0 0.0027 16.8 0.0 2.1 1 1 0 2 2 2 1 KaiC GH-E PF14410.1 EIW66528.1 - 0.22 11.6 3.7 5.1 7.3 0.5 2.3 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues PAH PF02671.16 EIW66529.1 - 0.12 12.0 0.5 0.4 10.3 0.3 1.9 1 1 0 1 1 1 0 Paired amphipathic helix repeat Rsd_AlgQ PF04353.8 EIW66529.1 - 2.1 8.0 7.9 0.2 11.3 1.1 2.3 3 0 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ AAA PF00004.24 EIW66530.1 - 1.8e-13 50.8 0.0 3.9e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EIW66530.1 - 8.4e-13 47.8 0.2 6.8e-06 25.0 0.0 3.0 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EIW66530.1 - 2.9e-06 27.4 0.0 1.7e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIW66530.1 - 5e-06 26.4 0.0 8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIW66530.1 - 2.8e-05 23.3 0.0 8.8e-05 21.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIW66530.1 - 6e-05 22.7 0.1 0.00019 21.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EIW66530.1 - 9.4e-05 23.2 0.1 0.00061 20.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW66530.1 - 0.00012 22.1 0.0 0.019 14.9 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EIW66530.1 - 0.00025 20.8 0.0 0.00047 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EIW66530.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EIW66530.1 - 0.0092 15.4 0.0 6 6.3 0.0 2.9 2 1 0 3 3 3 1 DEAD/DEAH box helicase DUF258 PF03193.11 EIW66530.1 - 0.0094 15.1 0.0 0.027 13.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 EIW66530.1 - 0.013 15.1 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.9 EIW66530.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EIW66530.1 - 0.024 14.9 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW66530.1 - 0.025 13.6 0.1 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 EIW66530.1 - 0.042 14.0 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 RNA helicase KaiC PF06745.8 EIW66530.1 - 0.058 12.4 0.0 0.38 9.8 0.0 2.0 1 1 1 2 2 2 0 KaiC IstB_IS21 PF01695.12 EIW66530.1 - 0.069 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EIW66530.1 - 0.072 12.7 0.1 0.18 11.5 0.0 1.6 2 0 0 2 2 1 0 NTPase UPF0079 PF02367.12 EIW66530.1 - 0.1 12.2 0.0 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EIW66530.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIW66530.1 - 0.11 11.8 0.1 0.97 8.7 0.0 2.4 2 1 1 3 3 2 0 AAA domain HLH PF00010.21 EIW66531.1 - 1.5e-11 43.8 0.8 3.5e-11 42.6 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.8 EIW66531.1 - 3.7 7.3 30.0 8.9 6.0 0.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF904 PF06005.7 EIW66532.1 - 0.005 17.1 4.8 9.5 6.5 0.0 3.1 1 1 1 2 2 1 0 Protein of unknown function (DUF904) DUF4200 PF13863.1 EIW66532.1 - 0.011 15.6 8.6 0.011 15.6 5.9 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF812 PF05667.6 EIW66532.1 - 0.011 14.2 8.6 0.016 13.7 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3584 PF12128.3 EIW66532.1 - 0.058 10.7 10.5 0.079 10.2 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) StbA PF06406.6 EIW66532.1 - 0.11 11.4 1.8 0.16 10.9 1.2 1.1 1 0 0 1 1 1 0 StbA protein Macoilin PF09726.4 EIW66532.1 - 0.16 10.2 18.9 0.025 12.8 9.5 1.6 1 1 1 2 2 2 0 Transmembrane protein Spc7 PF08317.6 EIW66532.1 - 0.28 9.8 16.1 0.32 9.6 6.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_lysis PF03245.8 EIW66532.1 - 0.34 10.9 5.1 0.37 10.7 0.0 2.5 1 1 0 2 2 2 0 Bacteriophage Rz lysis protein IncA PF04156.9 EIW66532.1 - 0.37 10.3 20.4 0.35 10.4 11.4 2.2 1 1 1 2 2 2 0 IncA protein FliJ PF02050.11 EIW66532.1 - 0.53 10.3 11.9 2.7 8.0 4.8 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein Phage_GP20 PF06810.6 EIW66532.1 - 0.76 9.2 11.5 3.4 7.0 2.1 2.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 FUSC PF04632.7 EIW66532.1 - 0.86 7.9 2.3 1.2 7.4 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.4 EIW66532.1 - 1.2 8.9 19.5 2.2 8.1 3.7 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 EIW66532.1 - 1.4 8.9 10.3 0.84 9.6 0.3 3.3 2 1 1 3 3 3 0 bZIP transcription factor DUF4140 PF13600.1 EIW66532.1 - 2.1 8.8 10.4 1.5 9.3 0.1 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 EIW66532.1 - 2.3 8.0 17.1 1.3 8.8 8.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 EIW66532.1 - 2.5 7.9 21.7 3.6 7.3 10.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 EIW66532.1 - 3 7.6 5.9 6.1 6.6 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 EIW66532.1 - 3.3 6.5 16.9 0.75 8.6 7.3 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EIW66532.1 - 3.4 7.5 22.0 6 6.7 1.1 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4559 PF15112.1 EIW66532.1 - 5.3 6.1 9.9 7.4 5.6 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) CENP-Q PF13094.1 EIW66532.1 - 7.8 6.5 19.3 15 5.5 13.4 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF641 PF04859.7 EIW66532.1 - 8.1 6.2 10.6 4.1 7.1 1.1 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4164 PF13747.1 EIW66532.1 - 8.5 6.5 16.0 2.9 8.0 1.1 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4164) Aldo_ket_red PF00248.16 EIW66533.1 - 3.8e-69 232.6 0.0 4.3e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RyR PF02026.11 EIW66533.1 - 0.017 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 RyR domain SNARE PF05739.14 EIW66534.1 - 2.8e-06 26.9 0.1 3.2e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EIW66534.1 - 0.0012 18.3 0.0 0.0014 18.1 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 TMP_2 PF06791.8 EIW66534.1 - 0.014 15.0 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein CHORD PF04968.7 EIW66535.1 - 4.1e-52 174.2 15.2 1.2e-26 92.7 2.9 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EIW66535.1 - 1e-13 51.5 0.1 1.2e-12 48.1 0.0 2.2 2 0 0 2 2 2 1 CS domain Hist_deacetyl PF00850.14 EIW66536.1 - 2.2e-96 322.7 0.1 4.3e-96 321.8 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EIW66536.1 - 1.7e-25 89.4 0.0 3.3e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain DUF1749 PF08538.5 EIW66536.1 - 0.00067 18.6 0.1 0.0016 17.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.8 EIW66536.1 - 0.0033 17.0 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_5 PF12695.2 EIW66536.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family MLANA PF14991.1 EIW66537.1 - 0.11 12.5 2.0 0.27 11.2 0.0 2.6 3 0 0 3 3 3 0 Protein melan-A DUF3675 PF12428.3 EIW66537.1 - 0.14 12.4 1.1 6.4 7.0 0.0 3.4 2 2 1 4 4 4 0 Protein of unknown function (DUF3675) NAD_binding_5 PF07994.7 EIW66538.1 - 1e-108 363.3 0.0 2.3e-108 362.1 0.0 1.5 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EIW66538.1 - 6.1e-44 148.4 1.5 7.8e-44 148.0 0.1 1.9 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase GDI PF00996.13 EIW66539.1 - 2.1e-52 177.9 0.0 2.9e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EIW66539.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW66539.1 - 0.014 14.2 0.0 0.83 8.4 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EIW66539.1 - 0.094 11.7 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HORMA PF02301.13 EIW66540.1 - 2.3e-46 157.9 0.5 2.7e-46 157.6 0.3 1.0 1 0 0 1 1 1 1 HORMA domain DUF2570 PF10828.3 EIW66540.1 - 0.098 12.2 1.2 0.18 11.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Snf7 PF03357.16 EIW66541.1 - 1.2e-41 141.9 16.8 1.2e-41 141.9 11.7 1.9 1 1 1 2 2 2 1 Snf7 RasGAP_C PF03836.10 EIW66541.1 - 0.34 10.5 4.6 0.26 10.9 1.3 2.1 2 1 0 2 2 2 0 RasGAP C-terminus Sterol-sensing PF12349.3 EIW66542.1 - 1.9e-33 115.0 7.4 1.1e-32 112.5 5.2 2.1 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EIW66542.1 - 9.5e-12 43.6 5.8 1.3e-11 43.2 4.0 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 EIW66542.1 - 0.0016 18.2 6.1 1.4 8.9 0.7 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat YesK PF14150.1 EIW66542.1 - 0.11 12.6 3.4 0.63 10.1 2.3 2.4 1 0 0 1 1 1 0 YesK-like protein DUF3608 PF12257.3 EIW66543.1 - 5.5e-57 192.8 0.0 7.7e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EIW66543.1 - 8.6e-19 67.0 0.2 1.7e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf-CCHC_3 PF13917.1 EIW66544.1 - 2e-17 62.6 3.9 2e-17 62.6 2.7 1.8 2 0 0 2 2 2 1 Zinc knuckle TFIIF_alpha PF05793.7 EIW66544.1 - 0.2 9.9 20.7 0.23 9.8 14.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 EIW66544.1 - 3.1 5.7 18.2 4.4 5.2 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 EIW66544.1 - 4.7 6.4 15.3 5.3 6.3 10.6 1.1 1 0 0 1 1 1 0 Vta1 like GATA PF00320.22 EIW66545.1 - 6.5e-14 50.9 3.5 9.8e-14 50.4 2.4 1.3 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.13 EIW66545.1 - 0.014 15.1 0.1 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Nudix_N_2 PF14803.1 EIW66545.1 - 0.032 13.9 0.5 0.062 12.9 0.3 1.4 1 1 0 1 1 1 0 Nudix N-terminal Fer4_2 PF12797.2 EIW66545.1 - 0.31 11.0 1.8 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Spc97_Spc98 PF04130.8 EIW66546.1 - 4.2e-119 398.3 0.0 5e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Spc97 / Spc98 family Hairy_orange PF07527.8 EIW66546.1 - 0.015 15.0 1.0 0.71 9.6 0.4 2.8 2 0 0 2 2 2 0 Hairy Orange Methyltransf_23 PF13489.1 EIW66547.1 - 0.011 15.4 0.1 0.19 11.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Glycolytic PF00274.14 EIW66547.1 - 0.092 11.1 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I TIM21 PF08294.6 EIW66548.1 - 1.7e-11 43.9 0.0 5.3e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 TIM21 Cpn60_TCP1 PF00118.19 EIW66549.1 - 1.8e-144 481.9 8.3 2.1e-144 481.8 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 EIW66549.1 - 0.0091 15.2 0.1 0.035 13.3 0.0 2.0 2 0 0 2 2 2 1 Telomere recombination DUF1688 PF07958.6 EIW66550.1 - 4.5e-148 493.2 0.0 5.1e-148 493.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Rhodanese PF00581.15 EIW66551.1 - 2e-12 47.4 0.0 4.5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain PepSY_TM_2 PF13703.1 EIW66553.1 - 0.064 13.4 0.5 0.1 12.7 0.3 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix DNA_pol_phi PF04931.8 EIW66554.1 - 1.9e-66 224.3 15.2 1.9e-66 224.3 10.6 2.6 3 0 0 3 3 3 1 DNA polymerase phi MutS_V PF00488.16 EIW66555.1 - 4e-77 258.7 0.0 6.6e-77 258.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIW66555.1 - 6.1e-30 104.5 0.3 1.3e-29 103.4 0.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EIW66555.1 - 1.2e-17 64.0 0.1 7.2e-13 48.5 0.0 2.6 2 0 0 2 2 2 2 MutS domain I MutS_IV PF05190.13 EIW66555.1 - 1e-10 41.6 0.0 2.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EIW66555.1 - 1.2e-08 35.1 0.0 2.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 EIW66555.1 - 0.048 13.1 0.0 0.15 11.6 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EIW66555.1 - 0.19 12.0 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 EIW66557.1 - 8.7e-67 225.6 26.6 1e-66 225.4 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW66557.1 - 5.7e-25 87.7 31.9 5.7e-25 87.7 22.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 EIW66558.1 - 2.3e-23 82.8 0.0 1.3e-19 70.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW66558.1 - 7.9e-11 41.9 0.0 1.4e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW66558.1 - 1.1e-08 34.6 0.0 0.0046 16.2 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 EIW66558.1 - 1.1e-08 34.2 0.0 8.4e-08 31.3 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EIW66558.1 - 1.9e-06 27.9 0.0 2.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW66558.1 - 5.6e-05 22.1 0.0 7.6e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EIW66558.1 - 0.0081 14.9 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase DUF2424 PF10340.4 EIW66558.1 - 0.047 12.3 0.0 0.087 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Peptidase_S15 PF02129.13 EIW66558.1 - 0.072 12.4 0.0 3.1 7.1 0.0 2.8 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EIW66558.1 - 0.078 11.4 0.0 0.19 10.2 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) BPL_N PF09825.4 EIW66559.1 - 6.2e-99 331.2 0.0 7.5e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EIW66559.1 - 6.6e-14 51.9 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.9 EIW66559.1 - 5.7e-05 22.7 0.0 9.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain APOC4 PF15119.1 EIW66559.1 - 0.09 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein C4 DUF367 PF04034.8 EIW66560.1 - 4.3e-47 158.8 0.0 5.4e-47 158.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EIW66560.1 - 2.4e-14 52.5 0.0 4.3e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI CAF1A PF12253.3 EIW66562.1 - 2.5e-23 81.9 9.8 5.5e-23 80.8 6.8 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A Ecl1 PF12855.2 EIW66563.1 - 1.9e-05 23.8 3.7 3.5e-05 23.0 2.6 1.4 1 0 0 1 1 1 1 Life-span regulatory factor PX PF00787.19 EIW66564.1 - 2.6e-23 81.9 0.8 8.6e-23 80.2 0.5 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EIW66564.1 - 7.2e-13 48.3 2.8 2.2e-07 30.3 1.0 2.3 2 0 0 2 2 2 2 Vps5 C terminal like TMF_TATA_bd PF12325.3 EIW66564.1 - 0.0075 15.9 1.9 1.3 8.7 0.0 2.4 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding GreA_GreB_N PF03449.10 EIW66564.1 - 0.04 13.9 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal WD40 PF00400.27 EIW66565.1 - 3.7e-32 109.0 19.4 2e-09 36.9 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PD40 PF07676.7 EIW66565.1 - 0.00051 19.6 2.0 1.3 8.7 0.0 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EIW66565.1 - 0.0038 15.8 0.1 0.023 13.3 0.0 2.1 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region SGL PF08450.7 EIW66565.1 - 0.0051 16.2 0.0 0.025 13.9 0.0 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region eIF2A PF08662.6 EIW66565.1 - 0.0085 15.8 0.3 0.5 10.0 0.0 2.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EIW66565.1 - 0.5 10.0 3.5 2.6 7.7 0.0 3.3 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term PhyH PF05721.8 EIW66566.1 - 4.1e-09 36.7 0.0 6.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ADH_N PF08240.7 EIW66567.1 - 3.5e-31 107.1 0.9 5.8e-31 106.4 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW66567.1 - 2.5e-15 56.1 0.0 3.6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW66567.1 - 3.8e-07 31.0 0.0 7.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EIW66567.1 - 0.0086 15.1 1.3 0.013 14.6 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.16 EIW66567.1 - 0.019 14.7 0.2 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 ThiF family DUF2318 PF10080.4 EIW66567.1 - 0.022 14.5 0.1 8.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) DUF2338 PF10100.4 EIW66567.1 - 0.066 11.5 0.0 0.094 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) Shikimate_DH PF01488.15 EIW66567.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase EF-hand_1 PF00036.27 EIW66568.1 - 1.6e-41 136.4 14.4 7.5e-11 40.5 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIW66568.1 - 1.8e-36 124.0 5.3 3e-21 75.2 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EIW66568.1 - 1.4e-32 111.0 11.7 4.5e-16 58.2 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EIW66568.1 - 5.4e-31 103.6 7.5 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIW66568.1 - 3.2e-26 89.4 9.9 3.1e-07 29.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EIW66568.1 - 3.2e-15 55.7 0.2 2.9e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EIW66568.1 - 1.5e-09 37.8 0.0 0.00029 20.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EIW66568.1 - 1.7e-08 33.9 0.8 0.0013 18.2 0.0 3.4 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.2 EIW66568.1 - 1.5e-07 31.0 2.7 0.00063 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EIW66568.1 - 1.3e-06 28.2 2.6 3.7e-06 26.8 0.5 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EIW66568.1 - 0.00026 20.7 0.5 0.069 12.8 0.1 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EIW66568.1 - 0.0014 18.2 0.2 0.1 12.1 0.0 2.5 1 1 0 2 2 2 1 Caleosin related protein DUF1103 PF06513.6 EIW66568.1 - 0.0026 17.2 3.5 0.0029 17.0 2.4 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF3349 PF11829.3 EIW66568.1 - 0.0095 16.3 0.2 13 6.2 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_like PF09279.6 EIW66568.1 - 0.016 15.2 1.8 0.11 12.5 0.2 2.5 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like LNS2 PF08235.8 EIW66568.1 - 0.031 13.8 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) RNA_pol_Rpb4 PF03874.11 EIW66568.1 - 0.046 13.7 2.1 6.4 6.8 0.1 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 Toprim_2 PF13155.1 EIW66568.1 - 0.048 13.9 2.4 6 7.2 0.6 2.6 1 1 1 2 2 2 0 Toprim-like Tenui_NCP PF04876.7 EIW66568.1 - 0.053 13.0 0.4 1.4 8.4 0.0 2.1 1 1 0 2 2 2 0 Tenuivirus major non-capsid protein MotA_activ PF09114.5 EIW66568.1 - 0.11 12.2 1.3 15 5.3 0.0 2.8 1 1 1 3 3 3 0 Transcription factor MotA, activation domain FlgD PF03963.9 EIW66568.1 - 0.3 11.1 1.9 2.7 8.1 0.1 2.5 3 0 0 3 3 2 0 Flagellar hook capping protein - N-terminal region EF-hand_10 PF14788.1 EIW66568.1 - 0.44 10.2 3.5 0.63 9.7 0.1 2.8 3 1 1 4 4 4 0 EF hand Ank_2 PF12796.2 EIW66569.1 - 0.017 15.4 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF3449 PF11931.3 EIW66569.1 - 0.058 12.8 0.1 0.058 12.8 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3449) Ank PF00023.25 EIW66569.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat zf-C2H2_jaz PF12171.3 EIW66569.1 - 0.43 10.7 2.2 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DEAD PF00270.24 EIW66570.1 - 5.5e-43 146.3 0.5 1e-42 145.4 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW66570.1 - 4.6e-27 93.6 0.1 1.1e-26 92.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EIW66570.1 - 0.00061 19.4 0.1 0.0017 18.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIW66570.1 - 0.023 14.8 0.2 0.079 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EIW66570.1 - 0.027 14.3 0.0 0.11 12.2 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.20 EIW66570.1 - 0.056 12.5 0.1 0.28 10.2 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) UvrD-helicase PF00580.16 EIW66570.1 - 0.057 12.7 0.1 0.071 12.3 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EIW66570.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Helicase DUF3449 PF11931.3 EIW66571.1 - 4.3e-60 202.6 1.4 1.4e-57 194.3 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EIW66571.1 - 2.4e-11 42.9 0.2 5.5e-11 41.7 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 EIW66571.1 - 3.5e-10 39.7 5.1 4.5e-06 26.6 0.6 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW66571.1 - 8.4e-10 38.5 4.5 0.00018 21.5 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-DBF PF07535.7 EIW66571.1 - 4.5e-06 26.2 1.1 0.029 14.0 0.1 2.6 2 0 0 2 2 2 2 DBF zinc finger zf-C2H2_2 PF12756.2 EIW66571.1 - 0.00017 21.6 0.8 0.56 10.3 0.1 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EIW66571.1 - 0.056 13.8 4.3 0.36 11.2 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type HTH_34 PF13601.1 EIW66571.1 - 0.071 13.1 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain zf-C2H2_4 PF13894.1 EIW66571.1 - 0.18 12.1 4.3 8.6 6.9 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW66571.1 - 2.5 8.1 4.4 10 6.1 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger WD40 PF00400.27 EIW66572.1 - 1.2e-42 142.3 18.6 8.1e-06 25.5 0.0 10.3 10 0 0 10 10 10 8 WD domain, G-beta repeat Gmad1 PF10647.4 EIW66572.1 - 3.2e-07 30.0 16.7 0.00015 21.3 0.1 4.5 3 2 2 5 5 5 3 Lipoprotein LpqB beta-propeller domain RAB3GAP2_N PF14655.1 EIW66572.1 - 0.00039 19.5 0.2 0.0028 16.7 0.0 2.2 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus CPSF_A PF03178.10 EIW66572.1 - 0.00067 18.8 0.0 0.031 13.3 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region PD40 PF07676.7 EIW66572.1 - 0.015 14.9 0.1 28 4.5 0.0 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EIW66572.1 - 0.13 10.0 0.0 1 7.1 0.0 2.0 2 0 0 2 2 2 0 IKI3 family MFS_1 PF07690.11 EIW66573.1 - 1.8e-17 63.1 18.2 7.6e-13 47.8 6.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_26 PF13659.1 EIW66574.1 - 4.6e-07 29.8 0.0 2.6e-06 27.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW66574.1 - 7.5e-05 22.3 0.0 0.00027 20.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW66574.1 - 0.0025 17.2 0.0 0.015 14.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EIW66574.1 - 0.0036 17.8 0.0 0.088 13.3 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW66574.1 - 0.0043 16.7 0.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain N6_Mtase PF02384.11 EIW66574.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.3 1 1 0 1 1 1 0 N-6 DNA Methylase UPF0020 PF01170.13 EIW66574.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Eco57I PF07669.6 EIW66574.1 - 0.15 12.4 0.1 0.36 11.2 0.0 1.6 2 0 0 2 2 2 0 Eco57I restriction-modification methylase ABC_tran PF00005.22 EIW66575.1 - 3.2e-45 153.8 1.2 9.6e-22 77.7 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EIW66575.1 - 2.7e-21 75.1 7.9 2.7e-21 75.1 5.5 2.7 2 1 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EIW66575.1 - 4.6e-15 56.3 1.3 0.0047 16.9 0.2 4.4 2 2 1 4 4 4 3 AAA domain AAA_17 PF13207.1 EIW66575.1 - 3.6e-10 40.7 0.2 0.0025 18.6 0.0 3.6 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 EIW66575.1 - 6.3e-09 35.3 7.0 0.0054 15.9 0.0 4.5 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain Miro PF08477.8 EIW66575.1 - 1.8e-08 34.9 0.1 0.012 16.1 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_22 PF13401.1 EIW66575.1 - 2.4e-08 34.2 0.1 0.015 15.3 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EIW66575.1 - 3.5e-08 33.5 0.1 0.006 16.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EIW66575.1 - 6e-08 32.1 0.1 0.0033 16.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EIW66575.1 - 6.7e-08 32.4 0.0 0.0057 16.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EIW66575.1 - 8.3e-07 29.1 1.1 0.012 15.6 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EIW66575.1 - 1.3e-06 27.6 0.0 0.04 13.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EIW66575.1 - 1.3e-06 28.7 0.5 0.19 12.0 0.0 3.7 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 EIW66575.1 - 1.4e-05 24.8 0.0 0.11 12.1 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EIW66575.1 - 1.7e-05 24.5 0.1 0.16 11.6 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 EIW66575.1 - 2.3e-05 24.0 0.1 0.18 11.1 0.0 3.6 4 0 0 4 4 4 2 AAA-like domain ArgK PF03308.11 EIW66575.1 - 2.9e-05 22.9 0.1 0.11 11.2 0.0 2.8 2 0 0 2 2 2 2 ArgK protein AAA_14 PF13173.1 EIW66575.1 - 4.2e-05 23.4 0.0 0.41 10.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 EIW66575.1 - 4.9e-05 23.4 0.0 0.058 13.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.18 EIW66575.1 - 5.5e-05 23.0 0.2 0.018 14.8 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_33 PF13671.1 EIW66575.1 - 8.8e-05 22.4 0.1 0.13 12.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 EIW66575.1 - 0.00023 21.0 0.2 0.074 12.9 0.1 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EIW66575.1 - 0.00045 19.3 2.3 1.9 7.4 0.0 3.8 3 2 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 EIW66575.1 - 0.00064 19.1 0.0 0.79 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EIW66575.1 - 0.0011 19.1 0.0 0.33 11.1 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EIW66575.1 - 0.0012 18.6 0.0 2.3 7.8 0.0 2.9 3 0 0 3 3 2 2 Archaeal ATPase PCP PF02429.10 EIW66575.1 - 0.0019 18.3 0.7 0.0047 17.0 0.5 1.6 1 0 0 1 1 1 1 Peridinin-chlorophyll A binding protein Septin PF00735.13 EIW66575.1 - 0.0076 15.2 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 1 Septin NTPase_1 PF03266.10 EIW66575.1 - 0.0089 15.7 0.1 2.5 7.7 0.0 3.0 3 0 0 3 3 2 1 NTPase AAA_5 PF07728.9 EIW66575.1 - 0.0097 15.6 0.1 11 5.7 0.0 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 EIW66575.1 - 0.011 15.2 0.7 0.86 9.0 0.0 2.8 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 EIW66575.1 - 0.011 15.1 0.4 6 6.2 0.0 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EIW66575.1 - 0.012 15.2 0.0 4.6 6.7 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 EIW66575.1 - 0.018 15.3 17.1 0.031 14.5 0.0 4.3 4 1 0 5 5 4 0 AAA domain Arf PF00025.16 EIW66575.1 - 0.048 12.8 0.5 12 5.1 0.0 3.4 3 0 0 3 3 3 0 ADP-ribosylation factor family ATP_bind_1 PF03029.12 EIW66575.1 - 0.058 12.9 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EIW66575.1 - 0.087 12.3 0.0 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EIW66575.1 - 0.092 12.2 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 EIW66575.1 - 0.2 11.4 0.0 0.2 11.4 0.0 4.0 5 1 0 5 5 3 0 Domain of unknown function DUF87 Adaptin_N PF01602.15 EIW66576.1 - 9.3e-95 317.9 0.0 5.2e-92 308.8 0.0 2.0 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EIW66576.1 - 5e-07 29.2 2.7 2.4 8.4 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EIW66576.1 - 2.3e-06 27.7 2.5 0.002 18.3 0.0 3.9 3 2 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 EIW66576.1 - 0.00034 21.0 0.2 4.4 7.9 0.0 4.2 3 0 0 3 3 3 1 HEAT-like repeat Sec7_N PF12783.2 EIW66576.1 - 0.016 14.6 0.6 0.04 13.3 0.4 1.6 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal tRNA-synt_His PF13393.1 EIW66577.1 - 6.6e-36 123.9 0.0 8.3e-31 107.1 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EIW66577.1 - 3.7e-17 62.4 0.0 8.5e-17 61.2 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIW66577.1 - 3.5e-08 33.2 0.1 6.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.15 EIW66577.1 - 0.014 14.6 0.0 0.05 12.7 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EIW66577.1 - 0.036 12.8 0.0 0.24 10.1 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) ABC_tran PF00005.22 EIW66578.1 - 1.2e-43 148.7 0.0 3.6e-26 92.0 0.1 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW66578.1 - 2.2e-41 142.1 28.1 7.5e-22 78.0 6.4 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EIW66578.1 - 8.6e-12 44.7 2.2 0.0024 17.1 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW66578.1 - 1.2e-11 45.1 2.0 0.0033 17.4 0.7 4.4 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EIW66578.1 - 5e-09 35.5 1.8 0.00024 20.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EIW66578.1 - 1.5e-07 31.7 0.0 0.01 16.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EIW66578.1 - 6.4e-07 28.5 1.7 0.019 13.8 0.2 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EIW66578.1 - 9.7e-07 29.6 0.1 0.096 13.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIW66578.1 - 3.2e-06 26.7 0.4 0.052 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW66578.1 - 5.7e-06 26.4 0.4 0.25 11.4 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIW66578.1 - 6.4e-06 26.2 4.5 0.01 15.8 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EIW66578.1 - 1.9e-05 25.1 10.1 0.00012 22.4 0.3 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EIW66578.1 - 3.1e-05 23.9 0.9 0.12 12.3 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EIW66578.1 - 4e-05 23.2 0.1 0.16 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.12 EIW66578.1 - 6.8e-05 22.7 2.4 0.021 14.6 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EIW66578.1 - 0.00017 21.1 0.5 0.59 9.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 EIW66578.1 - 0.00018 20.7 0.1 0.054 12.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EIW66578.1 - 0.00026 20.7 1.8 0.46 10.1 0.2 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EIW66578.1 - 0.0003 20.5 0.8 0.2 11.3 0.0 2.9 3 0 0 3 3 2 1 NTPase Adeno_IVa2 PF02456.10 EIW66578.1 - 0.00034 19.3 0.1 0.0014 17.3 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein Arch_ATPase PF01637.13 EIW66578.1 - 0.0012 18.6 0.0 0.046 13.4 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase Miro PF08477.8 EIW66578.1 - 0.0017 18.8 0.4 2.3 8.7 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 EIW66578.1 - 0.0018 18.4 0.0 1.8 8.7 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIW66578.1 - 0.0023 17.8 0.1 2.8 7.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIW66578.1 - 0.0027 17.3 1.1 1.5 8.3 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW66578.1 - 0.0031 17.2 0.8 0.23 11.2 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EIW66578.1 - 0.0039 16.3 0.7 1.4 7.9 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EIW66578.1 - 0.014 15.2 0.3 0.52 10.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.12 EIW66578.1 - 0.018 14.4 1.5 7.5 5.9 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EIW66578.1 - 0.02 15.0 0.1 6.6 6.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 EIW66578.1 - 0.02 14.0 0.5 1 8.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.4 EIW66578.1 - 0.037 12.6 0.4 1.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 EIW66578.1 - 0.041 13.6 0.4 3.3 7.4 0.0 3.0 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EIW66578.1 - 0.044 12.5 1.4 1.5 7.5 0.1 2.2 2 0 0 2 2 2 0 ArgK protein DUF815 PF05673.8 EIW66578.1 - 0.049 12.5 0.3 1.2 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.7 EIW66578.1 - 0.056 13.1 6.1 2 8.0 0.1 3.6 4 0 0 4 4 3 0 NACHT domain ATP-synt_ab PF00006.20 EIW66578.1 - 0.081 12.4 0.2 8.1 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.15 EIW66578.1 - 0.12 12.0 0.2 5.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase Dynamin_N PF00350.18 EIW66578.1 - 0.18 11.6 6.1 0.72 9.6 0.0 2.8 3 0 0 3 3 2 0 Dynamin family NB-ARC PF00931.17 EIW66578.1 - 0.2 10.5 1.9 1.5 7.6 0.1 2.7 3 0 0 3 3 3 0 NB-ARC domain ABC_ATPase PF09818.4 EIW66578.1 - 0.26 9.8 3.5 7.5 5.0 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF4557 PF15101.1 EIW66578.1 - 0.29 10.9 0.0 0.83 9.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) cobW PF02492.14 EIW66578.1 - 0.36 10.2 3.5 2.5 7.5 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DPBB_1 PF03330.13 EIW66579.1 - 2.2e-08 33.9 1.2 8.2e-08 32.1 0.8 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW66579.1 - 0.00018 21.1 0.9 0.00018 21.1 0.7 2.1 1 1 1 2 2 2 1 Barwin family Ins_beta PF03488.9 EIW66579.1 - 0.35 10.6 2.3 4.3 7.2 0.1 2.5 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Uds1 PF15456.1 EIW66580.1 - 3.6e-24 85.1 7.5 3.6e-24 85.1 5.2 5.8 4 3 1 5 5 5 3 Up-regulated During Septation Reo_sigmaC PF04582.7 EIW66580.1 - 7.9 5.5 15.3 0.28 10.3 1.4 3.3 3 0 0 3 3 3 0 Reovirus sigma C capsid protein VMA21 PF09446.5 EIW66581.1 - 2.7e-14 52.8 8.7 3.6e-14 52.4 6.0 1.2 1 0 0 1 1 1 1 VMA21-like domain Polysacc_synt_C PF14667.1 EIW66581.1 - 0.0084 15.9 3.2 0.0093 15.7 2.2 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain RRM_6 PF14259.1 EIW66582.1 - 2.7e-11 43.2 0.1 1.3e-09 37.9 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW66582.1 - 4e-10 39.1 1.7 1.3e-05 24.7 0.0 4.5 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Linker_histone PF00538.14 EIW66583.1 - 6.8e-13 48.5 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 linker histone H1 and H5 family HC2 PF07382.6 EIW66583.1 - 5.8 6.7 69.8 3e+02 1.1 48.4 2.5 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Endosulfine PF04667.12 EIW66584.1 - 3.8e-15 55.6 0.1 7.4e-15 54.6 0.0 1.6 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF3772 PF12607.3 EIW66585.1 - 0.3 10.7 0.1 0.3 10.7 0.1 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) GDC-P PF02347.11 EIW66587.1 - 3.8e-170 566.2 0.0 7.7e-162 538.8 0.0 2.5 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EIW66587.1 - 0.00064 18.9 0.0 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 Beta-eliminating lyase Brix PF04427.13 EIW66588.1 - 3.2e-52 176.9 0.0 4.2e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain ICMT PF04140.9 EIW66589.1 - 1.1e-24 86.4 0.8 2.1e-24 85.5 0.6 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW66589.1 - 1.6e-11 44.2 1.4 1.6e-11 44.2 1.0 1.5 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 EIW66589.1 - 8.3e-05 22.0 1.2 0.00013 21.4 0.8 1.3 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.7 EIW66589.1 - 0.022 14.0 0.6 0.029 13.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) HSA PF07529.8 EIW66590.1 - 2.8e-13 49.4 1.4 2.8e-13 49.4 1.0 3.3 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 EIW66590.1 - 9.8e-09 35.1 0.1 2.8e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIW66590.1 - 2.9e-07 30.4 0.2 8.2e-07 28.9 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cys_Met_Meta_PP PF01053.15 EIW66591.1 - 4.6e-25 87.7 0.0 5.8e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EIW66591.1 - 0.00087 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II p450 PF00067.17 EIW66593.1 - 1.1e-40 139.6 0.0 1.2e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thioredoxin PF00085.15 EIW66594.1 - 2.2e-22 78.7 0.0 2.6e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EIW66594.1 - 8.3e-09 35.6 0.0 1.3e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIW66594.1 - 6.3e-06 26.2 0.1 4.9e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EIW66594.1 - 1.7e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EIW66594.1 - 0.0016 18.1 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW66594.1 - 0.0017 17.9 0.5 0.044 13.3 0.1 2.1 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 EIW66594.1 - 0.0022 17.5 0.0 0.0027 17.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin KaiB PF07689.7 EIW66594.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 KaiB domain Glutaredoxin PF00462.19 EIW66594.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin MMR_HSR1 PF01926.18 EIW66595.1 - 2.1e-15 56.6 0.0 6.4e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW66595.1 - 2.9e-07 29.9 0.0 1.4e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EIW66595.1 - 8e-05 21.8 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIW66595.1 - 0.01 15.6 0.0 0.049 13.4 0.0 2.0 1 1 0 1 1 1 0 Dynamin family Miro PF08477.8 EIW66595.1 - 0.018 15.4 0.3 0.053 14.0 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 EIW66595.1 - 0.068 12.8 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EIW66595.1 - 0.13 10.9 0.0 0.28 9.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 EIW66595.1 - 0.14 13.0 0.5 1 10.2 0.0 2.7 3 1 0 3 3 3 0 AAA domain Phasin PF05597.6 EIW66596.1 - 0.39 10.4 7.9 0.91 9.2 0.7 2.6 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DDE_1 PF03184.14 EIW66597.1 - 3.3e-10 39.4 0.1 5.5e-09 35.4 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EIW66597.1 - 0.0014 18.1 0.1 0.0034 16.8 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EIW66597.1 - 0.0062 16.2 0.4 0.03 14.0 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Daxx PF03344.10 EIW66598.1 - 0.072 11.5 2.3 0.077 11.4 1.6 1.1 1 0 0 1 1 1 0 Daxx Family MSP1_C PF07462.6 EIW66598.1 - 0.23 9.8 5.1 0.29 9.4 3.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Jiv90 PF14901.1 EIW66599.1 - 0.05 13.5 0.1 0.28 11.2 0.0 2.0 1 1 1 2 2 2 0 Cleavage inducing molecular chaperone MULE PF10551.4 EIW66600.1 - 3.1e-13 49.7 1.4 1.2e-10 41.4 0.2 3.6 2 1 0 2 2 2 1 MULE transposase domain UCH PF00443.24 EIW66600.1 - 2.3e-09 36.7 0.0 6.3e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW66600.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DALR_2 PF09190.6 EIW66601.1 - 0.081 13.1 0.7 3.5 7.9 0.7 3.2 3 0 0 3 3 3 0 DALR domain DUF2120 PF09893.4 EIW66601.1 - 2.1 8.2 7.0 3.2 7.7 0.9 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) FlxA PF14282.1 EIW66601.1 - 3.7 7.5 30.2 0.32 10.9 6.2 3.1 1 1 1 2 2 2 0 FlxA-like protein Baculo_PEP_C PF04513.7 EIW66601.1 - 6 6.6 10.7 6.8 6.5 2.6 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.7 EIW66601.1 - 8.7 4.6 16.5 4.3 5.6 8.3 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family Ndc1_Nup PF09531.5 EIW66603.1 - 3.8 5.8 11.8 7 4.9 8.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIF_alpha PF05793.7 EIW66603.1 - 4.4 5.5 14.5 6.8 4.9 10.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HVSL PF09749.4 EIW66604.1 - 1.4e-18 66.8 0.1 2.6e-18 65.9 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein TruB_N PF01509.13 EIW66605.1 - 8.6e-42 142.8 0.0 2.3e-40 138.1 0.0 2.3 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) RGS PF00615.14 EIW66607.1 - 0.00014 21.9 0.0 0.00062 19.8 0.0 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain adh_short PF00106.20 EIW66608.1 - 9.2e-13 48.4 0.2 6.3e-10 39.2 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EIW66608.1 - 2.5e-07 30.5 0.4 2.5e-07 30.5 0.3 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EIW66608.1 - 0.00068 19.4 0.2 0.0054 16.5 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EIW66608.1 - 0.0095 15.2 0.2 0.017 14.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family PTPS PF01242.14 EIW66608.1 - 0.099 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase 3Beta_HSD PF01073.14 EIW66608.1 - 0.15 10.7 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SseC PF04888.7 EIW66609.1 - 0.8 8.9 9.4 1.2 8.3 6.5 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family MSP1_C PF07462.6 EIW66609.1 - 1.3 7.2 3.2 2 6.7 2.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Histone PF00125.19 EIW66610.1 - 4e-14 52.4 0.1 4.9e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW66610.1 - 3.7e-05 23.8 0.0 4.9e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIW66610.1 - 0.00011 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIW66610.1 - 0.0012 18.8 0.1 0.0025 17.8 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIW66610.1 - 0.046 12.9 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TRAPPC-Trs85 PF12739.2 EIW66611.1 - 1.9e-94 316.6 1.4 2.2e-94 316.4 0.3 1.5 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PK_C PF02887.11 EIW66611.1 - 0.044 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain TPR_16 PF13432.1 EIW66611.1 - 4 8.2 8.1 1.1 10.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L5_C PF00673.16 EIW66612.1 - 1.6e-13 50.1 0.0 4.1e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EIW66612.1 - 6.7e-05 22.5 0.1 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Rad4 PF03835.10 EIW66613.1 - 2.6e-07 30.1 0.4 5.1e-07 29.1 0.3 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EIW66613.1 - 2.7e-07 30.7 0.3 5.7e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily PKD_channel PF08016.7 EIW66614.1 - 0.048 12.0 4.1 0.099 11.0 2.8 1.6 1 0 0 1 1 1 0 Polycystin cation channel Cellulase PF00150.13 EIW66615.1 - 1e-16 60.9 0.0 1.5e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) USP7_ICP0_bdg PF12436.3 EIW66616.1 - 1.5e-83 279.9 0.1 4.6e-83 278.2 0.1 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EIW66616.1 - 5.6e-65 218.7 0.7 1.5e-60 204.3 0.0 3.2 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EIW66616.1 - 6.7e-57 192.6 0.1 1e-56 192.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW66616.1 - 1.5e-30 106.6 0.0 2.3e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EIW66616.1 - 4.8e-06 26.7 0.1 4.8e-05 23.5 0.0 2.8 3 1 0 3 3 3 1 MATH domain UN_NPL4 PF11543.3 EIW66616.1 - 0.13 12.5 0.3 6 7.2 0.1 3.3 2 1 0 3 3 3 0 Nuclear pore localisation protein NPL4 Sec66 PF09802.4 EIW66617.1 - 3.2e-48 163.6 0.0 3.6e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Pro_isomerase PF00160.16 EIW66618.1 - 4.5e-52 176.3 0.0 5e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MMR_HSR1 PF01926.18 EIW66619.1 - 1.2e-16 60.6 0.0 4.5e-15 55.6 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW66619.1 - 8.6e-06 25.1 0.0 5.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EIW66619.1 - 0.00058 19.0 0.0 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIW66619.1 - 0.0057 15.7 0.3 0.015 14.4 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 EIW66619.1 - 0.049 14.1 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Daxx PF03344.10 EIW66619.1 - 0.9 7.9 15.1 1.5 7.1 10.5 1.3 1 0 0 1 1 1 0 Daxx Family Ubiq_cyt_C_chap PF03981.7 EIW66620.1 - 1.1e-08 34.9 0.0 2.4e-07 30.6 0.0 2.6 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Coa1 PF08695.5 EIW66621.1 - 7.2e-33 112.5 0.0 9.8e-33 112.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ERG4_ERG24 PF01222.12 EIW66622.1 - 1.2e-128 429.4 20.6 1.4e-128 429.1 14.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family IMD PF08397.6 EIW66623.1 - 0.021 14.1 5.5 0.075 12.3 3.8 1.7 1 1 0 1 1 1 0 IRSp53/MIM homology domain Solute_trans_a PF03619.11 EIW66624.1 - 2.9e-100 335.1 7.4 3.5e-100 334.8 5.1 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DEAD PF00270.24 EIW66625.1 - 1.7e-32 112.2 0.0 8e-32 110.0 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW66625.1 - 7.1e-19 67.4 0.0 3.4e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EIW66625.1 - 1.2e-07 31.1 0.0 2.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EIW66625.1 - 0.00014 21.8 1.5 0.00058 19.7 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIW66625.1 - 0.0032 17.1 0.0 0.0089 15.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain SCO1-SenC PF02630.9 EIW66626.1 - 2.9e-53 180.0 0.0 3.6e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 EIW66626.1 - 3.5e-05 23.8 0.0 5.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EIW66626.1 - 0.00087 18.9 0.0 0.0017 18.0 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Muted PF14942.1 EIW66627.1 - 0.11 12.4 13.0 0.16 11.8 8.2 1.9 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF1423 PF07227.6 EIW66627.1 - 0.42 9.2 18.2 0.69 8.5 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) MULE PF10551.4 EIW66628.1 - 1.2e-14 54.2 0.1 1.4e-12 47.5 0.1 2.7 1 1 0 1 1 1 1 MULE transposase domain UCH PF00443.24 EIW66628.1 - 4.1e-08 32.6 0.0 6.3e-05 22.2 0.0 2.7 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF413 PF04219.7 EIW66629.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF DUF4614 PF15391.1 EIW66630.1 - 0.69 9.6 9.4 1.1 9.0 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SOG2 PF10428.4 EIW66630.1 - 2.9 6.4 12.7 3.5 6.1 8.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF822 PF05687.8 EIW66630.1 - 3.1 8.1 7.7 4.7 7.5 5.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Complex1_49kDa PF00346.14 EIW66631.1 - 3.4e-125 416.5 0.0 4.3e-125 416.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EIW66631.1 - 0.027 13.2 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Peptidase_M28 PF04389.12 EIW66632.1 - 3.7e-34 118.0 0.0 1.4e-33 116.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 UCR_UQCRX_QCR9 PF05365.7 EIW66633.1 - 8.3e-27 92.5 4.1 9.1e-27 92.4 2.9 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Tricorn_C1 PF14684.1 EIW66633.1 - 0.037 13.9 0.5 0.05 13.4 0.4 1.2 1 0 0 1 1 1 0 Tricorn protease C1 domain DUF4203 PF13886.1 EIW66633.1 - 0.062 12.7 0.0 0.062 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) B56 PF01603.15 EIW66634.1 - 2e-170 566.8 2.0 2.4e-170 566.5 1.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Ribosomal_L19 PF01245.15 EIW66635.1 - 2.4e-20 72.3 0.0 3e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 PIN_4 PF13638.1 EIW66636.1 - 2.4e-05 24.4 0.0 6e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 PIN domain DUF3425 PF11905.3 EIW66639.1 - 1.4e-18 67.1 1.1 2.2e-16 59.9 0.8 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EIW66639.1 - 2.1e-06 27.6 8.6 3e-05 23.8 6.0 2.3 1 1 0 1 1 1 1 bZIP transcription factor DUF4559 PF15112.1 EIW66639.1 - 0.21 10.7 0.1 0.31 10.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) zf-rbx1 PF12678.2 EIW66642.1 - 0.91 9.6 6.3 0.18 11.9 1.0 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger MFS_1 PF07690.11 EIW66643.1 - 0.0013 17.5 11.6 0.015 14.0 1.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Adeno_E3_CR1 PF02440.10 EIW66644.1 - 0.0021 17.4 0.0 6.6 6.2 0.0 3.1 3 0 0 3 3 3 2 Adenovirus E3 region protein CR1 VirionAssem_T7 PF11653.3 EIW66644.1 - 0.025 15.3 0.5 0.057 14.1 0.4 1.5 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein AP_endonuc_2 PF01261.19 EIW66644.1 - 0.032 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Phage-MuB_C PF09077.6 EIW66644.1 - 0.039 13.6 0.0 24 4.6 0.0 3.3 3 0 0 3 3 3 0 Mu B transposition protein, C terminal zf-C2H2_2 PF12756.2 EIW66646.1 - 0.0087 16.1 1.3 0.84 9.7 1.6 2.7 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EIW66646.1 - 0.025 14.9 1.4 0.025 14.9 1.0 4.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW66646.1 - 0.049 13.9 0.6 0.049 13.9 0.4 4.7 5 1 0 5 5 5 0 C2H2-type zinc finger DUF629 PF04780.7 EIW66646.1 - 0.05 12.1 2.0 0.052 12.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.3 EIW66646.1 - 0.4 10.8 6.6 0.45 10.7 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Lar_restr_allev PF14354.1 EIW66646.1 - 1.5 9.2 6.1 19 5.6 3.0 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar bact-PGI_C PF10432.4 EIW66649.1 - 0.088 12.5 0.5 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region CMV_1a PF12467.3 EIW66649.1 - 0.099 13.0 3.8 0.11 12.8 2.6 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF2058 PF09831.4 EIW66649.1 - 7.7 6.3 11.3 10 5.9 7.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) OTU PF02338.14 EIW66651.1 - 4.5e-11 43.3 0.0 5.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EIW66651.1 - 0.0069 15.7 0.0 0.0082 15.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain DUF3568 PF12092.3 EIW66651.1 - 0.026 14.2 0.0 0.047 13.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3568) zf-C2H2_2 PF12756.2 EIW66652.1 - 6.9 6.8 8.2 11 6.2 4.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TRI12 PF06609.8 EIW66653.1 - 3.4e-09 35.4 10.2 4.6e-09 35.0 7.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 EIW66653.1 - 0.0081 16.0 1.3 0.0081 16.0 0.9 3.6 3 0 0 3 3 3 1 Poxvirus virion envelope protein A14 DUF872 PF05915.7 EIW66653.1 - 0.25 11.2 3.8 0.16 11.8 0.5 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) MFS_1_like PF12832.2 EIW66653.1 - 5 6.9 13.7 0.058 13.1 0.8 3.0 3 0 0 3 3 3 0 MFS_1 like family Fungal_trans_2 PF11951.3 EIW66654.1 - 2.2e-29 102.2 0.1 6.1e-19 67.8 0.0 2.6 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW66654.1 - 3.8e-09 36.3 9.4 6.5e-09 35.5 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.1 EIW66655.1 - 6.1e-21 75.1 0.0 4.9e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW66655.1 - 2.8e-12 46.7 0.0 5.1e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.18 EIW66657.1 - 3.9e-12 46.4 0.0 6.7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW66657.1 - 1.2e-08 34.8 0.0 4.1e-08 33.0 0.0 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 EIW66657.1 - 0.0048 16.0 0.0 0.011 14.8 0.0 1.6 2 1 0 2 2 2 1 Protein kinase domain SH3BP5 PF05276.9 EIW66657.1 - 0.0082 15.4 0.1 0.95 8.7 0.6 2.1 2 0 0 2 2 2 2 SH3 domain-binding protein 5 (SH3BP5) DDE_Tnp_IS66 PF03050.9 EIW66657.1 - 0.042 13.0 0.1 0.058 12.6 0.1 1.2 1 0 0 1 1 1 0 Transposase IS66 family Myb_DNA-bind_4 PF13837.1 EIW66658.1 - 0.022 14.8 1.6 0.028 14.5 0.1 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain adh_short PF00106.20 EIW66663.1 - 9.8e-11 41.8 0.2 1.3e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW66663.1 - 1.8e-07 30.9 0.1 2.4e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 KR domain NTP_transf_3 PF12804.2 EIW66663.1 - 0.018 15.1 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain Shikimate_DH PF01488.15 EIW66663.1 - 0.024 14.7 0.2 0.038 14.1 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EIW66665.1 - 1.4e-24 86.5 49.1 5.8e-16 58.1 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1011 PF06237.7 EIW66665.1 - 2.4 8.0 10.6 1.5 8.7 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1011) PLDc PF00614.17 EIW66666.1 - 2.3e-13 49.4 0.5 2.9e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EIW66666.1 - 9.4e-11 41.5 0.0 4.3e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EIW66666.1 - 9.1e-10 38.3 0.0 3e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 PX domain N-glycanase_N PF09112.5 EIW66667.1 - 0.077 12.3 0.1 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Peptide-N-glycosidase F, N terminal DUF2587 PF10759.4 EIW66668.1 - 0.047 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW66669.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66669.1 - 0.27 11.5 9.2 0.069 13.3 4.2 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66669.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) UBN2_2 PF14227.1 EIW66670.1 - 6.7e-08 32.1 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW66670.1 - 4.2e-05 23.1 0.0 0.0047 16.4 0.0 2.5 3 0 0 3 3 3 2 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW66670.1 - 4.4e-05 23.2 0.0 8.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EIW66671.1 - 0.0022 17.8 1.9 0.0037 17.1 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW66671.1 - 0.045 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle BID PF06393.6 EIW66677.1 - 0.062 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 BH3 interacting domain (BID) PMT PF02366.13 EIW66678.1 - 1.9e-69 233.7 19.9 1.9e-69 233.7 13.8 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIW66678.1 - 9.5e-44 149.2 0.0 1.6e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 MIR domain GIDE PF12483.3 EIW66678.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 E3 Ubiquitin ligase PfUIS3 PF11567.3 EIW66681.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein HTH_Tnp_Tc3_2 PF01498.13 EIW66683.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Transposase Alpha_kinase PF02816.13 EIW66684.1 - 2.4e-14 53.4 0.0 3.3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family ACP_syn_III_C PF08541.5 EIW66685.1 - 0.025 14.5 0.0 0.085 12.8 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Histidinol_dh PF00815.15 EIW66691.1 - 3.2e-171 569.5 0.1 4.3e-171 569.1 0.1 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EIW66691.1 - 1.6e-23 82.1 0.1 3.3e-23 81.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EIW66691.1 - 9.3e-11 41.8 0.7 9.3e-11 41.8 0.5 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EIW66691.1 - 0.054 13.4 2.5 0.12 12.3 1.7 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Glyco_hydro_2_N PF02837.13 EIW66695.1 - 0.08 12.5 0.9 0.12 11.8 0.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain MMgT PF10270.4 EIW66696.1 - 5e-12 46.1 0.0 5e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Acatn PF13000.2 EIW66696.1 - 0.14 10.6 0.0 0.16 10.4 0.0 1.0 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 DDE_1 PF03184.14 EIW66698.1 - 1.1e-13 50.8 0.0 1.7e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EIW66698.1 - 0.0052 16.3 1.6 0.0061 16.0 0.1 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain BSP_II PF05432.6 EIW66700.1 - 0.0041 16.4 8.2 0.0069 15.7 5.7 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Fn3-like PF14310.1 EIW66700.1 - 0.025 14.5 0.0 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III-like domain DUF740 PF05340.7 EIW66700.1 - 0.065 11.6 6.8 0.082 11.2 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) CDC45 PF02724.9 EIW66700.1 - 0.096 10.6 8.4 0.11 10.4 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EIW66700.1 - 0.14 10.0 14.5 0.2 9.5 10.1 1.2 1 0 0 1 1 1 0 Nop14-like family CAML PF14963.1 EIW66700.1 - 0.19 11.0 4.8 0.33 10.2 3.3 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand eIF-3c_N PF05470.7 EIW66700.1 - 0.19 9.7 6.3 0.3 9.1 4.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRN3 PF05327.6 EIW66700.1 - 0.66 8.0 7.4 0.99 7.4 5.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_RNA_Pol_19 PF05320.7 EIW66700.1 - 1.2 8.8 9.7 2.8 7.6 6.8 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit ECIST_Cterm PF14784.1 EIW66700.1 - 2.1 8.3 5.3 17 5.3 0.1 2.7 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein Nucleoplasmin PF03066.10 EIW66700.1 - 4 6.9 22.2 7.1 6.1 0.1 3.1 3 0 0 3 3 3 0 Nucleoplasmin VID27 PF08553.5 EIW66700.1 - 4.4 5.4 12.5 6.1 4.9 8.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Lin-8 PF03353.10 EIW66700.1 - 5.5 6.1 9.8 3.1 7.0 4.2 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist TRAP_alpha PF03896.11 EIW66700.1 - 5.7 5.8 9.2 9.8 5.0 6.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Myc_N PF01056.13 EIW66700.1 - 6.7 5.7 13.8 9.7 5.2 8.1 2.0 2 0 0 2 2 2 0 Myc amino-terminal region DUF3872 PF12988.2 EIW66701.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) SNF2_N PF00176.18 EIW66702.1 - 1.2e-69 234.3 0.2 2.4e-69 233.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EIW66702.1 - 2.4e-37 128.0 16.2 2.4e-37 128.0 11.2 2.2 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.26 EIW66702.1 - 2.9e-14 52.6 0.0 6.1e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1751 PF08551.5 EIW66703.1 - 3.3e-28 97.8 0.3 3.3e-28 97.8 0.2 2.0 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EIW66703.1 - 9.9e-08 32.1 9.1 2e-07 31.1 6.3 1.5 1 0 0 1 1 1 1 Rhomboid family WD40 PF00400.27 EIW66704.1 - 2.8e-47 156.9 14.5 6.5e-11 41.6 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 EIW66704.1 - 5.6e-09 35.9 0.0 0.0025 17.5 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 EIW66704.1 - 5.8e-08 32.2 2.3 6.6e-08 32.0 0.4 2.0 2 0 0 2 2 2 1 LisH Apc4_WD40 PF12894.2 EIW66704.1 - 0.04 13.4 0.0 5.9 6.4 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 EIW66704.1 - 0.21 9.7 0.0 0.33 9.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) eIF-5_eIF-2B PF01873.12 EIW66706.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Ribosomal_L22e PF01776.12 EIW66709.1 - 8.7e-46 154.5 0.5 1e-45 154.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Homeobox_KN PF05920.6 EIW66711.1 - 9.7e-08 31.5 0.3 9.7e-08 31.5 0.2 3.0 3 0 0 3 3 3 1 Homeobox KN domain Mating_N PF12731.2 EIW66711.1 - 0.00099 18.9 0.2 0.0025 17.6 0.0 1.7 2 0 0 2 2 2 1 Mating-type protein beta 1 PG_binding_3 PF09374.5 EIW66711.1 - 0.093 12.7 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Homeobox PF00046.24 EIW66712.1 - 6.9e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Homeobox domain Reo_sigmaC PF04582.7 EIW66715.1 - 0.078 12.1 0.3 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein SKN1 PF03935.10 EIW66718.1 - 4e-206 685.0 5.8 5.1e-206 684.6 4.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF769 PF05590.6 EIW66719.1 - 0.1 11.8 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) DUF2587 PF10759.4 EIW66720.1 - 0.061 12.7 0.1 0.15 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW66721.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66721.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66721.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) HATPase_c PF02518.21 EIW66724.1 - 3.2e-13 49.3 0.0 7.9e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIW66724.1 - 2.4e-11 43.4 0.0 5.7e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EIW66724.1 - 1.8e-09 37.1 0.3 3e-08 33.1 0.2 2.3 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EIW66724.1 - 0.0026 17.3 0.0 0.029 13.9 0.0 2.5 1 1 1 2 2 2 1 MutL C terminal dimerisation domain Amidase PF01425.16 EIW66725.1 - 2.7e-95 319.8 0.2 3.5e-95 319.4 0.2 1.1 1 0 0 1 1 1 1 Amidase Scm3 PF10384.4 EIW66725.1 - 0.19 11.2 0.0 1.9 8.0 0.0 2.5 3 0 0 3 3 3 0 Centromere protein Scm3 SpvD PF05563.7 EIW66729.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD zf-CCHC PF00098.18 EIW66730.1 - 3.3e-06 26.7 7.1 6.6e-06 25.8 4.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW66730.1 - 0.0016 18.0 3.0 0.0041 16.7 2.1 1.7 1 0 0 1 1 1 1 Zinc knuckle Fumble PF03630.9 EIW66732.1 - 8.1e-111 370.1 0.0 1.7e-87 293.4 0.2 3.0 3 0 0 3 3 3 3 Fumble 2-oxoacid_dh PF00198.18 EIW66733.1 - 2.3e-81 272.4 0.0 3.1e-81 272.0 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIW66733.1 - 4.7e-19 67.7 2.9 1.1e-18 66.5 2.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EIW66733.1 - 9.3e-18 63.5 0.1 1.8e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 e3 binding domain Neisseria_TspB PF05616.8 EIW66733.1 - 0.89 7.8 5.4 1.5 7.1 3.7 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein CENP-B_dimeris PF09026.5 EIW66734.1 - 4.4 7.6 6.2 3.3 8.0 2.6 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain IPK PF03770.11 EIW66736.1 - 0.03 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Inositol polyphosphate kinase LAM_C PF12544.3 EIW66738.1 - 0.029 14.4 1.2 0.043 13.8 0.8 1.2 1 0 0 1 1 1 0 Lysine-2,3-aminomutase PPR_3 PF13812.1 EIW66739.1 - 2.3e-05 24.3 0.3 3.7 8.0 0.0 6.5 7 0 0 7 7 7 1 Pentatricopeptide repeat domain PPR PF01535.15 EIW66739.1 - 0.0024 17.7 3.4 2.1 8.5 0.0 4.4 4 0 0 4 4 4 2 PPR repeat TPR_2 PF07719.12 EIW66739.1 - 0.23 11.4 0.0 55 4.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ACBP PF00887.14 EIW66740.1 - 4.3e-26 90.4 0.0 4.8e-26 90.2 0.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Longin PF13774.1 EIW66742.1 - 1.4e-27 95.0 0.1 1.9e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EIW66742.1 - 2.3e-13 49.5 0.0 4.6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Nsp1_C PF05064.8 EIW66743.1 - 7.3e-13 48.1 4.5 6.2e-12 45.2 0.5 2.9 3 0 0 3 3 3 1 Nsp1-like C-terminal region EzrA PF06160.7 EIW66743.1 - 0.001 17.3 4.0 0.0044 15.2 0.1 2.0 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.7 EIW66743.1 - 0.013 15.3 6.1 0.18 11.6 3.0 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YjcZ PF13990.1 EIW66743.1 - 0.019 14.0 0.4 0.026 13.6 0.2 1.4 1 1 0 1 1 1 0 YjcZ-like protein AAA_13 PF13166.1 EIW66743.1 - 0.024 13.1 0.9 0.027 12.9 0.6 1.1 1 0 0 1 1 1 0 AAA domain SlyX PF04102.7 EIW66743.1 - 0.057 13.7 8.1 1.1 9.6 0.0 3.5 1 1 2 3 3 3 0 SlyX BLOC1_2 PF10046.4 EIW66743.1 - 0.079 13.1 5.6 1 9.5 0.4 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MscS_porin PF12795.2 EIW66743.1 - 0.081 12.2 6.9 0.31 10.3 0.3 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.1 EIW66743.1 - 0.13 11.1 1.4 0.16 10.8 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MbeD_MobD PF04899.7 EIW66743.1 - 0.17 11.7 3.6 3.1 7.7 0.1 3.1 3 0 0 3 3 3 0 MbeD/MobD like DUF919 PF06034.6 EIW66743.1 - 0.21 11.2 2.2 0.6 9.7 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) ATG16 PF08614.6 EIW66743.1 - 0.21 11.3 5.2 1.3 8.7 0.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.6 EIW66743.1 - 0.28 11.6 5.4 1.1 9.7 0.4 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal COG5 PF10392.4 EIW66743.1 - 0.35 10.8 4.8 1.2 9.1 2.2 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 NPV_P10 PF05531.7 EIW66743.1 - 0.36 11.0 6.3 4.8 7.5 0.6 3.1 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_S PF02609.11 EIW66743.1 - 0.41 10.4 5.5 0.96 9.2 0.1 3.1 3 0 0 3 3 3 0 Exonuclease VII small subunit Med8 PF10232.4 EIW66743.1 - 0.56 9.6 6.2 0.61 9.5 0.3 2.2 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 APG6 PF04111.7 EIW66743.1 - 0.57 9.1 5.1 4.7 6.1 0.0 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 Sec2p PF06428.6 EIW66743.1 - 0.64 9.8 5.9 0.67 9.8 0.1 2.6 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Prefoldin PF02996.12 EIW66743.1 - 1.2 8.7 6.3 2.4 7.8 0.6 2.8 3 0 0 3 3 3 0 Prefoldin subunit WXG100 PF06013.7 EIW66743.1 - 1.6 8.7 5.9 11 6.0 0.7 2.8 2 1 0 2 2 2 0 Proteins of 100 residues with WXG IncA PF04156.9 EIW66743.1 - 5.7 6.4 9.5 5.4 6.5 5.0 2.1 2 1 0 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 EIW66743.1 - 9.5 5.9 9.3 66 3.2 6.4 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PRP38 PF03371.10 EIW66744.1 - 2.3e-61 206.3 0.4 2.6e-61 206.2 0.3 1.0 1 0 0 1 1 1 1 PRP38 family CBFD_NFYB_HMF PF00808.18 EIW66745.1 - 1.3e-15 57.1 0.8 2.8e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3391 PF11871.3 EIW66745.1 - 0.018 15.2 0.1 0.024 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Bromo_TP PF07524.8 EIW66745.1 - 0.036 13.8 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated SMC_N PF02463.14 EIW66746.1 - 2.1e-54 184.0 46.3 7.3e-54 182.3 32.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIW66746.1 - 1.3e-29 102.6 0.9 4e-29 101.0 0.1 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EIW66746.1 - 9.5e-16 58.5 2.4 3e-07 30.7 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EIW66746.1 - 2.8e-08 34.3 44.0 2.8e-08 34.3 30.5 6.9 2 2 1 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 EIW66746.1 - 0.00028 20.1 27.5 0.019 14.1 0.6 5.5 2 2 3 5 5 5 4 Reovirus sigma C capsid protein PUL PF08324.6 EIW66746.1 - 0.0011 17.8 0.2 0.0011 17.8 0.1 3.5 4 0 0 4 4 4 1 PUL domain AAA_29 PF13555.1 EIW66746.1 - 0.0016 17.9 0.0 0.0039 16.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.2 EIW66746.1 - 0.0065 15.8 11.4 0.0065 15.8 7.9 6.6 3 2 3 6 6 6 1 Mechanosensitive ion channel porin domain HiaBD2 PF15403.1 EIW66746.1 - 0.12 12.5 0.4 1.3 9.2 0.1 3.0 3 0 0 3 3 3 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) AAA_27 PF13514.1 EIW66746.1 - 0.76 7.3 89.6 0.069 10.8 6.6 4.0 2 1 1 3 3 3 0 AAA domain SNase PF00565.12 EIW66747.1 - 4.2e-18 65.5 0.0 6.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ribosomal_S6e PF01092.14 EIW66748.1 - 4.5e-59 197.6 1.4 7e-59 197.0 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e Ku_C PF03730.9 EIW66748.1 - 0.042 14.3 4.2 0.69 10.4 0.1 2.3 1 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm Ribosomal_S13_N PF08069.7 EIW66749.1 - 5.3e-29 99.8 0.1 1.2e-28 98.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EIW66749.1 - 8.1e-20 70.3 0.1 1.2e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 DUF2695 PF10905.3 EIW66749.1 - 0.1 12.3 0.1 0.93 9.2 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2695) Afi1 PF07792.7 EIW66750.1 - 1.3e-40 138.7 0.0 2.3e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EIW66750.1 - 6.3e-34 116.0 0.0 1.1e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EIW66750.1 - 1.1e-08 33.9 0.0 0.0064 15.0 0.0 3.3 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 EIW66750.1 - 0.015 14.5 0.0 5.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) YscO PF07321.7 EIW66750.1 - 0.072 12.9 1.1 0.14 11.9 0.8 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO FA_desaturase PF00487.19 EIW66753.1 - 6.7e-21 74.8 25.2 3e-20 72.7 17.5 2.2 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EIW66753.1 - 0.00047 20.1 0.0 0.0011 18.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) SNF2_N PF00176.18 EIW66754.1 - 4.1e-65 219.5 0.0 6.4e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EIW66754.1 - 1e-42 146.1 0.2 1.8e-42 145.3 0.1 1.3 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EIW66754.1 - 1.5e-14 53.6 0.0 3.4e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIW66754.1 - 5.3e-08 32.0 0.0 1.6e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EIW66754.1 - 0.0007 19.1 0.0 0.066 12.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW66754.1 - 0.0013 18.6 0.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW66754.1 - 0.15 12.2 0.3 12 6.0 0.0 2.9 3 1 0 3 3 3 0 AAA domain RNA_pol_A_bac PF01000.21 EIW66755.1 - 8.1e-26 90.3 0.0 1.3e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EIW66755.1 - 2e-19 68.4 0.0 2.7e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PAP_assoc PF03828.14 EIW66756.1 - 8.2e-07 28.8 0.2 2.9e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 Cid1 family poly A polymerase UPF0052 PF01933.13 EIW66757.1 - 2.5e-42 145.2 0.0 3.6e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Herpes_DNAp_acc PF04929.7 EIW66757.1 - 0.025 13.5 0.1 0.091 11.7 0.0 1.7 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Tet_JBP PF12851.2 EIW66759.1 - 6.4e-09 35.3 0.0 7.7e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EIW66759.1 - 5.7e-07 29.9 0.1 1.3e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1394 PF07159.7 EIW66760.1 - 0.00028 20.1 0.0 0.00045 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Helitron_like_N PF14214.1 EIW66760.1 - 0.12 12.0 4.3 0.37 10.5 0.2 2.5 1 1 1 2 2 2 0 Helitron helicase-like domain at N-terminus Slu7 PF11708.3 EIW66761.1 - 2.5e-77 259.8 14.1 2.5e-77 259.8 9.7 2.6 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EIW66761.1 - 0.0059 16.2 0.8 0.015 14.9 0.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EIW66762.1 - 8e-08 31.8 11.3 9.9e-05 22.0 1.0 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EIW66762.1 - 1.8e-07 30.7 5.3 0.00019 21.0 1.4 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EIW66762.1 - 1.5e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EIW66762.1 - 0.00021 20.8 0.0 0.00045 19.7 0.0 1.6 1 0 0 1 1 1 1 KH domain DnaJ_CXXCXGXG PF00684.14 EIW66762.1 - 0.17 11.9 4.5 0.38 10.8 3.1 1.6 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_6 PF15288.1 EIW66762.1 - 0.84 9.3 10.1 2.3 7.9 1.7 2.5 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIW66762.1 - 1.1 9.0 4.9 7.6 6.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIW66762.1 - 4.5 6.8 10.0 5 6.7 0.3 3.3 2 1 1 3 3 3 0 Zinc knuckle LRR_4 PF12799.2 EIW66763.1 - 1e-12 47.3 35.1 8.9e-06 25.2 2.3 5.4 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW66763.1 - 3.7e-11 42.6 35.4 9.6e-07 28.4 4.5 4.2 1 1 5 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EIW66763.1 - 4.2e-06 26.0 35.5 0.61 10.3 0.5 9.2 9 0 0 9 9 9 5 Leucine Rich Repeat LRRNT_2 PF08263.7 EIW66763.1 - 0.00075 19.4 9.6 0.00075 19.4 6.7 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 EIW66763.1 - 0.08 13.1 24.0 31 5.4 0.2 8.3 7 1 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 EIW66763.1 - 0.82 9.9 34.9 21 5.5 0.1 7.8 6 1 1 7 7 7 0 Leucine Rich repeat Utp21 PF04192.7 EIW66765.1 - 4.8e-66 222.2 0.0 7e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EIW66765.1 - 2.1e-18 65.4 10.6 6.1e-06 25.9 0.0 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EIW66765.1 - 0.00058 19.6 0.0 0.25 11.0 0.0 4.0 4 2 2 6 6 6 1 Eukaryotic translation initiation factor eIF2A Utp12 PF04003.7 EIW66765.1 - 0.0027 17.5 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Hira PF07569.6 EIW66765.1 - 0.073 12.2 0.0 8.4 5.5 0.0 3.5 3 1 1 4 4 4 0 TUP1-like enhancer of split DUF3493 PF11998.3 EIW66766.1 - 1.1 9.2 5.6 3.1 7.7 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3493) ubiquitin PF00240.18 EIW66767.1 - 1.4e-22 78.8 0.3 2e-22 78.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EIW66767.1 - 2.8e-17 62.2 1.9 4.9e-17 61.4 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EIW66767.1 - 4.6e-14 51.8 0.1 6.3e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 EIW66767.1 - 0.0096 15.7 0.3 0.013 15.3 0.2 1.3 1 0 0 1 1 1 1 IBR domain RibD_C PF01872.12 EIW66767.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain Rad60-SLD_2 PF13881.1 EIW66767.1 - 0.017 14.9 0.1 0.099 12.5 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIW66767.1 - 0.02 15.0 0.1 0.034 14.3 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Telomere_Sde2 PF13019.1 EIW66767.1 - 0.021 14.4 0.4 0.03 13.9 0.1 1.4 1 1 0 1 1 1 0 Telomere stability and silencing Ubiquitin_2 PF14560.1 EIW66767.1 - 0.022 14.9 0.1 0.093 12.9 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain zf-C2H2_3 PF13878.1 EIW66767.1 - 0.12 11.9 0.1 0.36 10.4 0.1 1.8 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO KH_1 PF00013.24 EIW66768.1 - 3.2e-40 135.5 9.5 6.6e-15 54.5 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EIW66768.1 - 1.4e-30 104.4 12.9 4.8e-11 42.0 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EIW66768.1 - 1.3e-11 43.8 5.4 0.0026 17.2 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EIW66768.1 - 2.3e-08 33.5 1.9 0.0088 15.6 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EIW66768.1 - 0.00016 21.4 3.4 0.48 10.2 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EIW66768.1 - 0.019 14.4 0.1 0.9 9.0 0.0 2.4 2 0 0 2 2 2 0 dUTPase DUF221 PF02714.10 EIW66769.1 - 8.5e-63 212.1 13.3 1.6e-62 211.2 9.2 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIW66769.1 - 4.8e-09 35.9 12.3 3.8e-08 33.0 0.3 3.4 4 0 0 4 4 4 2 Late exocytosis, associated with Golgi transport DUF1479 PF07350.7 EIW66769.1 - 0.043 12.2 0.4 1 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) NIF PF03031.13 EIW66770.1 - 5e-50 169.2 0.0 9.2e-50 168.4 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HemY_N PF07219.8 EIW66770.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus PfkB PF00294.19 EIW66771.1 - 2.9e-12 46.3 0.0 2.1e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MerE PF05052.7 EIW66771.1 - 0.029 14.3 0.3 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 MerE protein Phos_pyr_kin PF08543.7 EIW66771.1 - 0.15 11.2 0.0 8.7 5.4 0.0 2.4 3 0 0 3 3 3 0 Phosphomethylpyrimidine kinase NIF PF03031.13 EIW66772.1 - 1.4e-19 70.2 0.0 2.1e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 EIW66772.1 - 0.00045 19.5 0.0 0.00094 18.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Glyco_transf_90 PF05686.7 EIW66773.1 - 8.8e-12 44.4 0.3 1.9e-11 43.3 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 90 TGT PF01702.13 EIW66774.1 - 0.089 12.0 0.1 0.22 10.7 0.0 1.6 1 1 0 1 1 1 0 Queuine tRNA-ribosyltransferase Daxx PF03344.10 EIW66774.1 - 0.29 9.5 32.5 0.43 9.0 22.5 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EIW66774.1 - 0.38 8.6 26.3 0.79 7.5 18.3 1.4 2 0 0 2 2 2 0 Nop14-like family IncA PF04156.9 EIW66774.1 - 2.7 7.5 9.2 5.1 6.6 6.4 1.5 1 0 0 1 1 1 0 IncA protein GRP PF07172.6 EIW66774.1 - 6.1 7.4 9.1 13 6.3 6.3 1.6 1 0 0 1 1 1 0 Glycine rich protein family DDHD PF02862.12 EIW66774.1 - 6.1 6.5 7.3 12 5.6 5.0 1.4 1 0 0 1 1 1 0 DDHD domain Mur_ligase_C PF02875.16 EIW66775.1 - 0.083 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain PIP5K PF01504.13 EIW66777.1 - 1.5e-59 201.1 0.1 2.8e-59 200.2 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EIW66777.1 - 1.1e-25 90.2 0.0 1.7e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EIW66777.1 - 6e-17 61.3 13.5 1.4e-16 60.1 9.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger Ion_trans PF00520.26 EIW66778.1 - 1.1e-98 328.4 85.5 2.6e-31 108.4 10.2 5.3 5 0 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 EIW66778.1 - 0.041 13.1 0.1 0.096 12.0 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EIW66778.1 - 0.066 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain RdRP_3 PF00998.18 EIW66778.1 - 0.18 10.2 0.1 0.29 9.5 0.1 1.2 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase DUF4203 PF13886.1 EIW66783.1 - 6.6e-20 71.4 16.0 8.5e-20 71.1 11.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Rad60-SLD PF11976.3 EIW66784.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DKCLD PF08068.7 EIW66785.1 - 3.8e-29 100.3 0.1 6e-28 96.5 0.1 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EIW66785.1 - 4e-24 85.4 0.3 5e-21 75.4 0.2 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EIW66785.1 - 6.7e-22 77.0 2.1 1.6e-21 75.8 1.5 1.7 1 0 0 1 1 1 1 PUA domain Peptidase_M18 PF02127.10 EIW66786.1 - 3e-139 464.2 0.0 3.7e-139 463.9 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EIW66786.1 - 3.9e-08 32.4 0.1 7.8e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Ribosomal_S17e PF00833.13 EIW66787.1 - 5.5e-55 184.3 0.1 9.4e-55 183.6 0.0 1.4 2 0 0 2 2 2 1 Ribosomal S17 CAF-1_p150 PF11600.3 EIW66788.1 - 0.047 13.0 18.6 0.046 13.0 12.9 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNase_H2-Ydr279 PF09468.5 EIW66788.1 - 3.6 6.6 10.9 4.1 6.5 7.6 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Aconitase PF00330.15 EIW66789.1 - 8.6e-176 584.9 0.1 2.1e-175 583.6 0.1 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIW66789.1 - 2.5e-45 153.7 0.0 4.1e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2587 PF10759.4 EIW66790.1 - 0.046 13.1 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) SR-25 PF10500.4 EIW66790.1 - 0.57 9.6 28.7 0.083 12.3 9.1 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Nop14 PF04147.7 EIW66791.1 - 0.0032 15.4 5.1 0.0045 14.9 3.6 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2587 PF10759.4 EIW66791.1 - 0.048 13.0 0.1 0.15 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) SDA1 PF05285.7 EIW66791.1 - 0.15 11.2 7.5 0.26 10.5 5.2 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EIW66791.1 - 0.39 8.6 3.3 0.54 8.2 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NAP PF00956.13 EIW66793.1 - 1.7e-23 83.0 11.7 4.7e-23 81.5 8.1 1.6 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Peptidase_S3 PF00944.14 EIW66793.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Alphavirus core protein Ribosomal_S7 PF00177.16 EIW66794.1 - 1.3e-20 73.4 0.5 1.6e-20 73.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e WD40 PF00400.27 EIW66795.1 - 9.5e-28 95.0 6.5 4.1e-11 42.3 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EIW66795.1 - 1e-14 54.1 0.0 2.2e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EIW66795.1 - 3.5e-06 26.8 0.1 7.2e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Lipase_3 PF01764.20 EIW66796.1 - 6.1e-07 29.1 0.0 2.1e-06 27.3 0.0 1.8 1 1 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIW66796.1 - 0.013 15.2 0.3 0.09 12.5 0.2 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EIW66796.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF865 PF05906.6 EIW66796.1 - 0.28 10.7 2.9 0.7 9.5 2.0 1.6 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) Ribosomal_L32p PF01783.18 EIW66797.1 - 5.6e-13 48.8 8.5 7.9e-13 48.3 5.9 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family DUF1272 PF06906.6 EIW66797.1 - 0.044 13.6 0.5 0.069 13.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.7 EIW66797.1 - 0.049 13.4 0.5 0.075 12.8 0.3 1.2 1 0 0 1 1 1 0 zinc-ribbons NRDD PF13597.1 EIW66797.1 - 0.057 11.4 0.7 0.067 11.2 0.5 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase DZR PF12773.2 EIW66797.1 - 0.061 13.1 0.7 0.092 12.5 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 EIW66797.1 - 0.098 12.3 1.9 0.16 11.6 1.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Methyltransf_16 PF10294.4 EIW66798.1 - 2.2e-33 115.1 0.0 2.9e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EIW66798.1 - 2e-06 27.6 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIW66798.1 - 0.0041 16.2 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EIW66798.1 - 0.0072 15.7 0.1 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EIW66798.1 - 0.029 14.9 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF726 PF05277.7 EIW66799.1 - 1.8e-120 401.9 3.0 2.5e-120 401.4 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Adeno_E3B PF03376.9 EIW66800.1 - 0.14 12.0 3.7 0.4 10.6 2.5 1.8 1 1 0 1 1 1 0 Adenovirus E3B protein DUF3481 PF11980.3 EIW66800.1 - 0.52 10.1 2.2 0.63 9.9 0.7 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF3481) Spore_permease PF03845.8 EIW66800.1 - 2.6 6.6 8.8 4.4 5.8 6.1 1.5 1 1 0 1 1 1 0 Spore germination protein Cyclin_N PF00134.18 EIW66801.1 - 7.4e-06 25.5 0.0 1.9e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ribosomal_S14 PF00253.16 EIW66802.1 - 2.1e-18 65.4 1.1 3.8e-18 64.5 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF2587 PF10759.4 EIW66803.1 - 0.046 13.0 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) CIMR PF00878.13 EIW66804.1 - 1.4e-11 44.3 0.0 0.00013 21.8 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 EIW66804.1 - 0.016 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor DUF939_C PF11728.3 EIW66805.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 DUF939 C-terminal domain Hydrolase_6 PF13344.1 EIW66806.1 - 9.8e-17 60.7 0.0 2.4e-16 59.4 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW66806.1 - 4.8e-08 32.5 0.0 1.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EIW66806.1 - 0.00022 21.5 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW66806.1 - 0.012 15.9 0.0 2.3 8.5 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Lipase_3 PF01764.20 EIW66807.1 - 7.8e-10 38.5 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EIW66807.1 - 0.013 15.3 0.5 0.02 14.8 0.3 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Toxin_18 PF08087.6 EIW66808.1 - 0.7 9.7 5.1 14 5.5 0.8 2.7 3 0 0 3 3 3 0 Conotoxin O-superfamily Velvet PF11754.3 EIW66809.1 - 5e-55 186.2 0.0 6.2e-54 182.6 0.0 2.1 1 1 0 1 1 1 1 Velvet factor NOP5NT PF08156.8 EIW66810.1 - 0.11 12.6 0.1 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 NOP5NT (NUC127) domain HALZ PF02183.13 EIW66811.1 - 0.015 15.0 2.1 0.04 13.6 1.5 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper GAS PF13851.1 EIW66811.1 - 0.016 14.4 0.9 0.021 14.0 0.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.1 EIW66811.1 - 0.15 12.0 3.1 1 9.3 0.6 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 IncA PF04156.9 EIW66811.1 - 0.51 9.8 3.9 0.12 11.9 0.9 1.5 2 1 0 2 2 2 0 IncA protein Herpes_BLRF2 PF05812.7 EIW66812.1 - 0.014 15.1 1.4 0.024 14.4 0.2 1.9 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Clathrin_bdg PF15045.1 EIW66812.1 - 0.026 14.0 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking TPD52 PF04201.10 EIW66812.1 - 0.035 13.8 0.9 0.057 13.1 0.6 1.3 1 0 0 1 1 1 0 Tumour protein D52 family DUF4200 PF13863.1 EIW66812.1 - 0.045 13.7 2.8 0.079 12.9 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DivIC PF04977.10 EIW66812.1 - 0.062 12.8 2.0 0.12 11.9 1.4 1.4 1 0 0 1 1 1 0 Septum formation initiator Seryl_tRNA_N PF02403.17 EIW66812.1 - 0.088 12.8 1.1 0.21 11.5 0.3 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 EIW66812.1 - 0.53 10.0 5.4 0.75 9.5 1.6 2.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper Bap31 PF05529.7 EIW66812.1 - 0.63 9.4 3.0 1.2 8.5 2.1 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like bZIP_2 PF07716.10 EIW66812.1 - 1.3 8.8 4.8 2.5 7.9 2.8 1.8 1 1 1 2 2 2 0 Basic region leucine zipper Aminotran_1_2 PF00155.16 EIW66813.1 - 0.14 11.0 0.1 0.25 10.2 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class I and II MxiH PF09392.5 EIW66816.1 - 0.14 12.7 0.1 0.14 12.7 0.1 4.1 3 1 0 3 3 3 0 Type III secretion needle MxiH like MFS_1 PF07690.11 EIW66817.1 - 1.2e-28 99.8 33.6 1.2e-28 99.8 23.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pep3_Vps18 PF05131.9 EIW66818.1 - 1.1e-36 125.4 0.0 3.4e-36 123.8 0.0 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EIW66818.1 - 5.3e-08 32.5 4.4 0.00013 21.5 0.1 3.2 3 1 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EIW66818.1 - 0.0031 17.3 1.2 0.0067 16.2 0.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EIW66818.1 - 0.0057 16.3 0.3 0.0057 16.3 0.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain DUF1664 PF07889.7 EIW66818.1 - 0.21 11.3 0.2 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MFS_1 PF07690.11 EIW66819.1 - 2e-54 184.6 19.7 2.6e-53 180.9 13.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW66819.1 - 1.5e-15 56.7 8.0 1.5e-15 56.7 5.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EIW66819.1 - 1.3e-07 30.2 5.2 1.3e-07 30.2 3.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EIW66819.1 - 0.00087 17.7 11.8 0.00087 17.7 8.2 3.8 3 2 1 4 4 4 1 MFS/sugar transport protein DUF1534 PF07551.6 EIW66819.1 - 0.019 14.4 0.0 0.079 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1534) MFS_1_like PF12832.2 EIW66819.1 - 0.099 12.4 8.1 0.35 10.6 0.4 3.2 3 0 0 3 3 3 0 MFS_1 like family MFS_3 PF05977.8 EIW66819.1 - 0.17 9.9 9.4 0.093 10.8 3.7 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Pkinase PF00069.20 EIW66820.1 - 5.3e-37 127.3 0.0 6.5e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW66820.1 - 4.6e-13 48.8 0.0 1.4e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW66820.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1331 PF07048.6 EIW66820.1 - 0.083 12.3 0.1 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) TF_AP-2 PF03299.9 EIW66822.1 - 0.088 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Transcription factor AP-2 UCH PF00443.24 EIW66824.1 - 7.2e-29 100.7 0.0 2.6e-28 98.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EIW66824.1 - 4.9e-10 39.3 0.0 8.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EIW66824.1 - 1.4e-06 27.9 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-CCHC PF00098.18 EIW66829.1 - 0.0023 17.7 1.9 0.0039 17.0 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW66829.1 - 0.051 13.3 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIW66831.1 - 0.8 9.7 4.3 1.4 9.0 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle GLTT PF01744.15 EIW66833.1 - 1.2e-15 56.5 0.0 1.1e-05 24.6 0.0 2.8 1 1 0 2 2 2 2 GLTT repeat (6 copies) PIF1 PF05970.9 EIW66835.1 - 1.4e-22 80.1 0.0 2e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIW66835.1 - 0.00022 20.8 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW66835.1 - 0.0007 19.6 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EIW66835.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EIW66835.1 - 0.0036 16.9 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.11 EIW66835.1 - 0.055 12.6 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 EIW66835.1 - 0.061 12.2 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EIW66835.1 - 0.19 10.5 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Baculo_PEP_C PF04513.7 EIW66837.1 - 2.1e-06 27.5 1.2 3.1e-06 27.0 0.9 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EIW66837.1 - 0.00014 21.2 0.7 0.00017 20.8 0.5 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein WEMBL PF05701.6 EIW66837.1 - 0.00063 18.3 0.0 0.00081 17.9 0.0 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light LPP PF04728.8 EIW66837.1 - 0.0016 18.2 2.3 0.0037 17.0 1.5 1.7 1 1 0 1 1 1 1 Lipoprotein leucine-zipper FlaC_arch PF05377.6 EIW66837.1 - 0.0034 17.2 0.8 0.041 13.7 0.5 2.2 1 1 0 1 1 1 1 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EIW66837.1 - 0.011 15.4 0.2 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2353 PF09789.4 EIW66837.1 - 0.02 14.1 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) NPV_P10 PF05531.7 EIW66837.1 - 0.041 14.1 0.6 0.086 13.1 0.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein COG7 PF10191.4 EIW66837.1 - 0.055 11.3 0.1 0.071 11.0 0.1 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF972 PF06156.8 EIW66837.1 - 0.081 13.2 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TBPIP PF07106.8 EIW66837.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 EIW66837.1 - 0.093 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Paramyx_P_V_C PF03210.8 EIW66837.1 - 0.098 12.5 0.4 0.42 10.4 0.3 1.9 1 1 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal ADIP PF11559.3 EIW66837.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 EIW66837.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper She9_MDM33 PF05546.6 EIW66837.1 - 0.13 11.7 0.1 0.19 11.2 0.1 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family Macoilin PF09726.4 EIW66837.1 - 0.15 10.3 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Daxx PF03344.10 EIW66838.1 - 4.8e-06 25.3 21.9 4.8e-06 25.3 15.2 1.9 2 0 0 2 2 2 1 Daxx Family Nop14 PF04147.7 EIW66838.1 - 1.2e-05 23.5 25.6 1.2e-05 23.5 17.8 1.9 2 0 0 2 2 2 1 Nop14-like family IncA PF04156.9 EIW66838.1 - 0.00071 19.2 4.9 0.0011 18.5 3.4 1.2 1 0 0 1 1 1 1 IncA protein SDA1 PF05285.7 EIW66838.1 - 0.0021 17.3 23.9 0.0021 17.3 16.5 2.1 2 0 0 2 2 2 1 SDA1 Spore_coat_CotO PF14153.1 EIW66838.1 - 0.0024 17.3 20.3 0.0046 16.4 14.1 1.4 1 0 0 1 1 1 1 Spore coat protein CotO Ycf1 PF05758.7 EIW66838.1 - 0.012 13.3 10.8 0.016 12.9 7.5 1.1 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 EIW66838.1 - 0.098 11.2 6.9 0.13 10.8 4.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1510 PF07423.6 EIW66838.1 - 0.19 11.0 28.7 0.48 9.7 19.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_gE PF02480.11 EIW66838.1 - 0.24 9.6 1.1 0.39 8.9 0.7 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Pox_Ag35 PF03286.9 EIW66838.1 - 0.38 10.2 17.0 0.79 9.2 11.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Plasmodium_Vir PF05795.6 EIW66838.1 - 0.44 9.6 6.6 0.82 8.8 4.6 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SpoIIIAH PF12685.2 EIW66838.1 - 0.61 9.5 17.2 0.022 14.2 7.4 1.8 2 0 0 2 2 2 0 SpoIIIAH-like protein Hid1 PF12722.2 EIW66838.1 - 1.2 6.6 6.6 1.4 6.4 4.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Astro_capsid PF03115.9 EIW66838.1 - 2.2 6.4 7.2 2.9 6.0 5.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor HSP90 PF00183.13 EIW66838.1 - 2.5 6.3 26.6 4 5.7 18.4 1.3 1 0 0 1 1 1 0 Hsp90 protein DUF2052 PF09747.4 EIW66838.1 - 2.6 7.9 33.7 0.51 10.2 18.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Mpp10 PF04006.7 EIW66838.1 - 3.5 5.8 37.4 6 5.1 25.9 1.3 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.7 EIW66838.1 - 3.5 7.4 26.7 0.1 12.4 13.8 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 EIW66838.1 - 6.3 4.7 28.1 0.0053 14.8 11.6 1.5 2 0 0 2 2 1 0 CDC45-like protein Tim54 PF11711.3 EIW66838.1 - 7.9 4.9 18.4 14 4.1 12.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 zf-CCHC PF00098.18 EIW66840.1 - 0.013 15.3 1.9 0.027 14.4 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIW66842.1 - 0.0023 17.7 1.9 0.0041 16.9 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle FLO_LFY PF01698.11 EIW66842.1 - 0.14 10.9 0.7 0.3 9.8 0.0 1.7 2 0 0 2 2 2 0 Floricaula / Leafy protein DDE_3 PF13358.1 EIW66843.1 - 7.6e-08 32.2 0.2 8.8e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Myosin_head PF00063.16 EIW66844.1 - 4e-36 124.3 30.1 8.2e-18 63.8 0.1 5.9 5 1 1 6 6 6 4 Myosin head (motor domain) CPSase_L_D3 PF02787.14 EIW66850.1 - 0.0037 17.0 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_23 PF13384.1 EIW66850.1 - 0.018 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain GerE PF00196.14 EIW66850.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Rootletin PF15035.1 EIW66851.1 - 0.012 15.5 8.1 0.026 14.5 5.6 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion OmpH PF03938.9 EIW66851.1 - 0.026 14.4 7.3 0.052 13.4 5.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EIW66851.1 - 0.13 11.8 14.6 0.81 9.2 10.1 2.1 1 1 0 1 1 1 0 IncA protein DUF334 PF03904.8 EIW66851.1 - 0.19 11.0 5.5 0.27 10.5 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF334) SlyX PF04102.7 EIW66851.1 - 0.51 10.7 9.6 1.7 9.1 0.0 4.0 2 1 2 4 4 4 0 SlyX DUF883 PF05957.8 EIW66851.1 - 1.5 9.2 13.2 29 5.1 0.0 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) ADIP PF11559.3 EIW66851.1 - 1.6 8.6 13.0 1.3 8.9 0.6 2.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2203 PF09969.4 EIW66851.1 - 3.6 7.8 5.6 19 5.5 3.0 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF972 PF06156.8 EIW66851.1 - 6.5 7.1 15.2 10 6.5 0.0 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EIW66851.1 - 6.9 7.0 15.9 45 4.4 0.1 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Myosin_head PF00063.16 EIW66852.1 - 2.1e-15 55.8 0.0 3.7e-05 22.0 0.0 3.5 3 0 0 3 3 3 3 Myosin head (motor domain) DUF4571 PF15137.1 EIW66852.1 - 0.15 11.5 0.9 5.9 6.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4571) B5 PF03484.10 EIW66853.1 - 0.15 11.9 0.3 0.26 11.1 0.2 1.3 1 0 0 1 1 1 0 tRNA synthetase B5 domain DDE_1 PF03184.14 EIW66860.1 - 2.9e-26 91.9 0.0 6.2e-26 90.8 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EIW66860.1 - 1.5e-05 24.4 0.0 4.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EIW66860.1 - 0.00027 20.7 0.2 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_Tc3_2 PF01498.13 EIW66860.1 - 2.2 8.4 5.5 4.9 7.2 0.1 3.1 3 0 0 3 3 3 0 Transposase DUF4357 PF14267.1 EIW66861.1 - 0.039 13.5 0.1 58 3.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4357) Periviscerokin PF08259.6 EIW66861.1 - 0.059 13.4 5.0 98 3.5 0.0 5.0 5 0 0 5 5 5 0 Periviscerokinin family SH2 PF00017.19 EIW66862.1 - 0.00043 20.0 0.1 5 7.0 0.0 3.9 4 0 0 4 4 4 2 SH2 domain Periviscerokin PF08259.6 EIW66862.1 - 0.0061 16.4 4.4 1.4e+02 3.1 0.0 5.8 6 0 0 6 6 6 0 Periviscerokinin family SH3_2 PF07653.12 EIW66862.1 - 0.017 14.6 0.4 75 2.9 0.0 4.6 5 0 0 5 5 5 0 Variant SH3 domain MULE PF10551.4 EIW66863.1 - 3.6e-09 36.6 0.0 8.4e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain zf-C3HC4 PF00097.20 EIW66864.1 - 9.2e-10 38.0 18.8 6.2e-09 35.3 8.5 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW66864.1 - 2.3e-07 30.7 18.6 4.3e-06 26.6 9.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW66864.1 - 2e-06 27.5 20.0 2.6e-06 27.1 9.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW66864.1 - 2.5e-06 27.0 13.9 4.9e-06 26.1 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW66864.1 - 4.9e-05 23.1 16.4 0.00034 20.4 9.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIW66864.1 - 0.00035 20.2 11.0 0.00035 20.2 7.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 EIW66864.1 - 0.02 14.4 11.6 0.52 9.9 6.5 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Yippee-Mis18 PF03226.9 EIW66864.1 - 0.023 14.7 0.8 0.17 11.9 0.2 2.2 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 EIW66864.1 - 0.024 14.4 8.0 0.25 11.2 4.4 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-rbx1 PF12678.2 EIW66864.1 - 0.12 12.4 13.4 0.11 12.6 7.5 2.1 2 1 0 2 2 2 0 RING-H2 zinc finger UPF0547 PF10571.4 EIW66864.1 - 0.18 11.5 0.2 0.18 11.5 0.2 3.7 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-UDP PF14569.1 EIW66864.1 - 0.2 11.4 7.4 0.13 12.0 3.6 1.9 2 1 0 2 2 2 0 Zinc-binding RING-finger zf-Apc11 PF12861.2 EIW66864.1 - 0.45 10.3 6.8 0.1 12.4 2.2 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EIW66864.1 - 0.55 9.9 12.0 0.42 10.3 5.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 EIW66864.1 - 0.63 9.8 11.0 0.38 10.5 5.6 2.1 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-AD PF07776.10 EIW66864.1 - 1.8 8.6 7.7 0.15 12.0 0.4 2.6 2 2 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Vps39_2 PF10367.4 EIW66864.1 - 2.8 8.1 0.0 2.8 8.1 0.0 3.4 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Rubredoxin PF00301.15 EIW66864.1 - 3.2 7.7 10.4 14 5.6 4.5 3.1 2 1 0 2 2 2 0 Rubredoxin IBR PF01485.16 EIW66864.1 - 9 6.2 14.8 13 5.7 7.3 3.0 2 1 0 2 2 2 0 IBR domain Acetyltransf_1 PF00583.19 EIW66865.1 - 1.7e-13 50.3 0.0 3.2e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW66865.1 - 1.3e-08 34.8 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW66865.1 - 0.00061 19.9 0.0 0.00078 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW66865.1 - 0.0035 17.4 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GCFC PF07842.7 EIW66866.1 - 6.4e-76 255.3 4.7 6.4e-76 255.3 3.2 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 EIW66866.1 - 4.2e-10 39.6 13.5 4.2e-10 39.6 9.4 2.6 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.18 EIW66866.1 - 1.2e-07 31.3 0.8 1.2e-07 31.3 0.6 3.3 3 0 0 3 3 3 1 G-patch domain MMR_HSR1 PF01926.18 EIW66867.1 - 1.5e-17 63.5 0.0 2.9e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EIW66867.1 - 1.9e-17 62.8 0.0 3.3e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EIW66867.1 - 1.2e-11 44.1 0.0 2.1e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EIW66867.1 - 0.00047 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIW66867.1 - 0.0021 17.9 0.9 0.036 13.8 0.0 2.4 2 1 1 3 3 3 1 Dynamin family MCM PF00493.18 EIW66867.1 - 0.016 14.0 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family Dynamin_N PF00350.18 EIW66868.1 - 2e-16 60.2 0.1 5e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EIW66868.1 - 4e-11 42.8 0.0 2.4e-10 40.3 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW66868.1 - 7.8e-11 41.7 0.1 1.9e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIW66868.1 - 0.00029 21.3 0.0 0.02 15.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 EIW66868.1 - 0.00051 19.5 0.1 0.78 9.1 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EIW66868.1 - 0.0034 16.8 0.0 0.0081 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.13 EIW66868.1 - 0.017 14.3 0.1 3.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Arf PF00025.16 EIW66868.1 - 0.038 13.2 0.2 1.7 7.8 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF258 PF03193.11 EIW66868.1 - 0.052 12.7 0.0 0.3 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 PACT_coil_coil PF10495.4 EIW66869.1 - 4e-21 74.7 0.7 2.6e-20 72.1 0.1 2.9 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein GST_N PF02798.15 EIW66869.1 - 0.095 12.8 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain WD40 PF00400.27 EIW66871.1 - 1.7e-11 43.5 9.1 8.6e-06 25.4 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ISAV_HA PF06215.6 EIW66871.1 - 0.066 11.5 0.3 0.094 11.0 0.2 1.2 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin Rhomboid PF01694.17 EIW66872.1 - 8.1e-33 113.4 7.6 8.1e-33 113.4 5.3 1.9 3 0 0 3 3 3 1 Rhomboid family PX PF00787.19 EIW66873.1 - 1.3e-17 63.6 0.0 2.3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 PX domain DUF2805 PF10985.3 EIW66873.1 - 0.092 12.6 1.1 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) UCR_hinge PF02320.11 EIW66874.1 - 3.9e-19 68.3 2.7 6.1e-19 67.7 1.9 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Prothymosin PF03247.9 EIW66874.1 - 0.18 11.9 16.8 0.32 11.1 11.7 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family DFF-C PF09033.5 EIW66874.1 - 0.23 11.2 1.5 0.33 10.7 1.1 1.2 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Sigma70_ner PF04546.8 EIW66874.1 - 0.42 10.2 8.4 0.52 9.8 5.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.11 EIW66874.1 - 0.51 9.2 3.7 0.64 8.9 2.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Na_trans_assoc PF06512.8 EIW66874.1 - 0.63 9.9 8.5 0.76 9.6 5.9 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated ANAPC15 PF15243.1 EIW66874.1 - 0.66 10.0 14.5 1.4 9.0 10.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 Daxx PF03344.10 EIW66874.1 - 0.66 8.3 11.1 0.68 8.3 7.7 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EIW66874.1 - 1.3 6.8 7.8 1.3 6.8 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family CHCH PF06747.8 EIW66874.1 - 1.9 8.5 5.6 9.3 6.3 1.6 2.4 2 0 0 2 2 2 0 CHCH domain CDC45 PF02724.9 EIW66874.1 - 5.1 5.0 6.2 5.6 4.8 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 EIW66874.1 - 5.2 6.5 9.8 6.1 6.2 6.8 1.1 1 0 0 1 1 1 0 PPP4R2 Paf1 PF03985.8 EIW66874.1 - 5.3 5.6 7.3 5.5 5.6 5.0 1.1 1 0 0 1 1 1 0 Paf1 DUF77 PF01910.12 EIW66875.1 - 8e-30 102.3 0.0 9.9e-30 102.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 EIW66875.1 - 0.043 13.9 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 YKOF-related Family DUF3349 PF11829.3 EIW66875.1 - 0.068 13.6 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) adh_short PF00106.20 EIW66876.1 - 2.6e-18 66.5 0.9 4.7e-18 65.6 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW66876.1 - 7e-09 35.6 0.9 9.6e-09 35.1 0.6 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW66876.1 - 8.5e-06 25.7 0.1 0.014 15.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 EIW66876.1 - 8.9e-05 21.5 0.0 0.0003 19.7 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EIW66876.1 - 0.004 16.6 0.2 0.008 15.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EIW66876.1 - 0.0041 16.1 0.1 0.0063 15.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EIW66876.1 - 0.06 13.3 0.2 0.24 11.3 0.1 2.3 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIW66876.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EIW66876.1 - 0.15 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Pkinase PF00069.20 EIW66877.1 - 8.7e-54 182.3 0.0 1e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW66877.1 - 3e-46 157.5 0.0 3.5e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW66877.1 - 0.0066 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIW66877.1 - 0.073 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 EIW66877.1 - 0.18 10.6 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TP_methylase PF00590.15 EIW66878.1 - 2.3e-19 69.9 0.0 3.3e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DinB_2 PF12867.2 EIW66879.1 - 1.1e-06 28.9 0.1 2.8e-06 27.6 0.1 1.6 1 1 0 1 1 1 1 DinB superfamily MDMPI_N PF11716.3 EIW66879.1 - 0.00045 20.6 0.2 0.0012 19.3 0.1 1.6 1 1 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB PF05163.7 EIW66879.1 - 0.015 14.9 0.1 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 DinB family DUF3628 PF12300.3 EIW66880.1 - 0.017 15.1 3.2 0.027 14.5 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) DUF2216 PF10226.4 EIW66880.1 - 0.082 12.4 1.7 1.2 8.5 1.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) EF-hand_10 PF14788.1 EIW66881.1 - 0.1 12.2 0.2 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 EF hand UBN2_3 PF14244.1 EIW66883.1 - 0.00027 20.5 0.1 0.00034 20.1 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW66884.1 - 0.0016 17.9 0.1 1.1 8.8 0.1 2.1 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW66884.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TLD PF07534.11 EIW66885.1 - 2.8e-30 105.1 0.1 4.5e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 TLD DUF3321 PF11968.3 EIW66886.1 - 4e-66 222.7 0.0 5.6e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EIW66886.1 - 0.0072 16.0 0.0 0.031 13.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW66886.1 - 0.087 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PGAP1 PF07819.8 EIW66887.1 - 8.1e-59 198.9 0.1 1.1e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EIW66887.1 - 1.2e-06 28.0 0.1 3.1e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EIW66887.1 - 5.4e-06 26.4 0.1 7.3e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW66887.1 - 5.6e-06 26.1 0.0 9.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW66887.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EIW66887.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Esterase PF00756.15 EIW66887.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 Putative esterase DUF2305 PF10230.4 EIW66887.1 - 0.047 13.0 0.2 0.088 12.2 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EIW66887.1 - 0.081 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 EIW66887.1 - 0.17 11.2 0.0 0.53 9.6 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) TauD PF02668.11 EIW66889.1 - 9.7e-36 123.7 0.0 1.5e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EIW66889.1 - 0.18 10.6 0.0 8.2 5.2 0.0 2.1 2 0 0 2 2 2 0 CsiD TPT PF03151.11 EIW66890.1 - 2e-32 111.9 4.3 2e-32 111.9 3.0 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EIW66890.1 - 7.2e-10 38.2 13.7 9.3e-10 37.9 9.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIW66890.1 - 1.4e-08 34.8 28.4 5.1e-05 23.3 3.6 2.9 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EIW66890.1 - 0.03 13.4 0.8 0.21 10.6 0.0 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter MitMem_reg PF13012.1 EIW66891.1 - 7e-17 61.5 0.1 1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EIW66891.1 - 2.9e-16 59.2 0.0 6.1e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Glyco_transf_8 PF01501.15 EIW66892.1 - 4.5e-18 65.4 0.0 5.1e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EIW66892.1 - 0.0025 17.6 1.3 0.0092 15.7 0.9 1.7 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 EIW66892.1 - 0.071 12.4 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative ACBP PF00887.14 EIW66893.1 - 1.8e-19 69.1 0.0 2.8e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.1 EIW66893.1 - 1.3e-15 57.0 0.2 4e-13 49.1 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW66893.1 - 2.5e-13 50.1 0.6 2.4e-06 27.8 0.1 2.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EIW66893.1 - 2.8e-13 48.9 0.0 9.6e-10 37.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EIW66893.1 - 5.9e-13 48.9 0.0 8.9e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIW66893.1 - 1.2e-08 34.3 0.0 3.1e-06 26.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Vps8 PF12816.2 EIW66894.1 - 9.4e-40 135.9 2.1 4e-31 107.7 0.1 3.6 1 1 1 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EIW66894.1 - 2.2e-06 27.3 0.1 0.028 14.0 0.0 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS RhoGEF PF00621.15 EIW66895.1 - 2.2e-31 109.1 0.1 4.1e-31 108.2 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain Dscam_C PF12355.3 EIW66895.1 - 0.069 13.4 0.3 0.069 13.4 0.2 2.4 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal MSC PF09402.5 EIW66895.1 - 0.21 10.2 0.5 0.72 8.5 0.7 1.5 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain DUF972 PF06156.8 EIW66895.1 - 6.9 7.0 14.4 8 6.8 1.5 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF972) Sel1 PF08238.7 EIW66896.1 - 1.3e-44 149.6 32.9 3.6e-09 36.9 0.0 7.6 7 0 0 7 7 7 7 Sel1 repeat TPR_17 PF13431.1 EIW66896.1 - 2.4 8.5 5.9 15 6.0 0.0 4.5 4 2 0 4 4 4 0 Tetratricopeptide repeat Chorismate_bind PF00425.13 EIW66897.1 - 4.5e-86 288.3 0.0 8.9e-86 287.3 0.0 1.5 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EIW66897.1 - 1.3e-28 99.7 0.0 4.6e-28 97.9 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region MFS_1 PF07690.11 EIW66898.1 - 1.9e-34 118.9 44.8 1.9e-34 118.9 31.1 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW66898.1 - 3.1e-12 45.5 22.3 3.9e-10 38.5 15.4 2.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW66898.1 - 2.1e-09 36.4 12.7 2.1e-09 36.4 8.8 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter CAP PF00188.21 EIW66899.1 - 6.6e-16 58.9 0.8 6.6e-16 58.9 0.6 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Cut8_N PF14482.1 EIW66899.1 - 0.089 12.7 1.4 0.19 11.7 1.0 1.5 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Aminotran_1_2 PF00155.16 EIW66900.1 - 2.3e-56 191.3 0.0 2.6e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIW66900.1 - 0.00026 20.1 0.0 0.00041 19.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EIW66900.1 - 0.0024 17.0 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EIW66900.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DDHD PF02862.12 EIW66901.1 - 2.5e-36 125.6 4.9 1.3e-21 77.4 0.0 4.1 4 0 0 4 4 4 2 DDHD domain Abhydrolase_6 PF12697.2 EIW66901.1 - 0.027 14.3 0.0 0.084 12.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family FSH1 PF03959.8 EIW66901.1 - 0.032 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EIW66901.1 - 0.034 13.9 0.0 0.12 12.1 0.0 1.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EIW66901.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Chalcone PF02431.10 EIW66902.1 - 3.8e-42 143.9 0.0 7.7e-26 90.7 0.0 2.1 2 0 0 2 2 2 2 Chalcone-flavanone isomerase ZZ PF00569.12 EIW66903.1 - 6e-12 44.9 48.2 1.7e-06 27.4 1.9 6.0 6 0 0 6 6 6 3 Zinc finger, ZZ type PB1 PF00564.19 EIW66903.1 - 4.8e-09 35.7 0.0 9.1e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 PB1 domain DUF35_N PF12172.3 EIW66903.1 - 5.9 6.9 20.3 0.38 10.7 0.3 4.0 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Complex1_30kDa PF00329.14 EIW66905.1 - 4.2e-36 123.3 0.0 6.2e-36 122.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Fasciclin PF02469.17 EIW66906.1 - 2.6e-55 185.8 0.1 4.9e-16 58.8 0.0 7.3 6 2 0 6 6 6 5 Fasciclin domain 2OG-FeII_Oxy_3 PF13640.1 EIW66906.1 - 0.028 14.9 0.6 1.7 9.1 0.0 3.1 3 0 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily DASH_Ask1 PF08655.5 EIW66907.1 - 4.9e-23 80.7 0.0 8.6e-23 79.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 UCH PF00443.24 EIW66908.1 - 3.6e-48 164.0 0.0 4.7e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW66908.1 - 6.6e-15 55.3 0.0 1.6e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EIW66908.1 - 7.6e-07 29.1 5.4 7.6e-07 29.1 3.7 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein SEO_C PF14577.1 EIW66908.1 - 0.091 12.1 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Ribosomal_S19 PF00203.16 EIW66909.1 - 4.6e-33 112.6 0.1 6.3e-33 112.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DNA_pol_E_B PF04042.11 EIW66910.1 - 1.5e-44 151.7 0.0 2e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Not3 PF04065.10 EIW66911.1 - 5e-90 300.8 18.4 7.2e-90 300.3 12.7 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EIW66911.1 - 2e-41 141.0 9.9 5.7e-41 139.5 6.8 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family FbpA PF05833.6 EIW66911.1 - 0.015 13.9 12.4 0.039 12.4 8.6 1.7 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF948 PF06103.6 EIW66911.1 - 0.13 12.1 2.6 2.2 8.2 0.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.8 EIW66911.1 - 0.71 9.2 6.0 0.23 10.8 1.7 2.0 2 0 0 2 2 2 0 fzo-like conserved region Poty_PP PF08440.5 EIW66911.1 - 1.1 8.2 5.8 0.27 10.2 1.8 1.5 2 0 0 2 2 2 0 Potyviridae polyprotein Syntaxin_2 PF14523.1 EIW66911.1 - 2.5 8.1 9.1 0.28 11.2 1.4 2.6 2 1 0 2 2 2 0 Syntaxin-like protein zf-CCCH PF00642.19 EIW66912.1 - 8.9e-08 31.6 0.9 1.7e-07 30.7 0.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribonuclease_3 PF00636.21 EIW66913.1 - 3.2e-13 50.1 0.1 8.2e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIW66913.1 - 1.2e-07 31.6 0.3 5e-07 29.7 0.0 2.1 2 1 1 3 3 3 1 Ribonuclease-III-like dsrm PF00035.20 EIW66913.1 - 0.026 15.1 0.2 0.049 14.2 0.1 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EIW66914.1 - 3.5e-07 30.2 0.0 5.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIW66914.1 - 7e-07 29.6 0.0 1.6e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 EIW66914.1 - 8.5e-05 23.0 0.5 0.00033 21.1 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif Condensin2nSMC PF12422.3 EIW66914.1 - 0.09 12.5 0.1 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit DND1_DSRM PF14709.1 EIW66915.1 - 6.8e-05 23.0 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EIW66915.1 - 0.0025 18.3 2.0 0.0066 17.0 0.0 2.6 3 2 0 3 3 3 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EIW66915.1 - 0.037 14.4 0.1 0.11 12.9 0.1 1.8 1 1 0 1 1 1 0 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIW66915.1 - 0.045 13.7 0.1 0.077 12.9 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease-III-like HTH_33 PF13592.1 EIW66915.1 - 0.084 12.4 0.8 0.23 11.0 0.3 1.9 2 0 0 2 2 2 0 Winged helix-turn helix FAT PF02259.18 EIW66917.1 - 4.2e-114 381.2 2.0 7.7e-114 380.3 0.1 2.3 2 1 1 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 EIW66917.1 - 1.9e-55 187.9 0.3 3.8e-55 186.9 0.1 1.6 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EIW66917.1 - 8.7e-51 172.0 6.4 2.1e-50 170.7 0.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EIW66917.1 - 1.4e-38 130.9 0.0 6.9e-38 128.7 0.0 2.4 1 0 0 1 1 1 1 Rapamycin binding domain FATC PF02260.15 EIW66917.1 - 1.7e-12 46.4 0.0 4.4e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 EIW66917.1 - 1.5e-08 34.8 7.7 0.0057 17.0 0.0 8.2 10 1 1 11 11 11 2 HEAT-like repeat HEAT PF02985.17 EIW66917.1 - 3.3e-05 23.6 10.1 0.41 10.8 0.0 8.8 10 0 0 10 10 10 1 HEAT repeat Xpo1 PF08389.7 EIW66917.1 - 0.0028 17.5 0.3 2.1 8.2 0.0 5.0 4 1 0 4 4 4 1 Exportin 1-like protein TPR_7 PF13176.1 EIW66917.1 - 0.072 12.9 0.5 11 6.1 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIW66917.1 - 0.26 11.3 3.5 16 5.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_pol_Rpc34 PF05158.7 EIW66918.1 - 5e-55 186.9 8.7 7.7e-46 156.7 0.0 3.1 1 1 2 3 3 3 2 RNA polymerase Rpc34 subunit RPA_C PF08784.6 EIW66918.1 - 8.8e-06 26.0 0.2 8.8e-06 26.0 0.1 3.0 4 0 0 4 4 4 1 Replication protein A C terminal MIP-T3 PF10243.4 EIW66918.1 - 0.001 17.6 56.3 0.0016 17.0 39.0 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF572 PF04502.8 EIW66918.1 - 0.0039 16.4 45.2 0.0074 15.5 31.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF572) Acetyltransf_13 PF13880.1 EIW66919.1 - 0.06 13.1 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Frataxin_Cyay PF01491.11 EIW66922.1 - 0.069 12.9 0.1 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 Frataxin-like domain TENA_THI-4 PF03070.11 EIW66923.1 - 0.049 13.3 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family DUF4149 PF13664.1 EIW66925.1 - 1.9e-19 69.5 1.2 3.6e-19 68.6 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Peptidase_S10 PF00450.17 EIW66926.1 - 1.2e-108 363.9 0.1 1.6e-108 363.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIW66926.1 - 0.0011 18.9 0.0 0.0083 16.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family V4R PF02830.13 EIW66926.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 V4R domain DUF1509 PF07420.6 EIW66927.1 - 0.072 12.3 4.3 0.074 12.3 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DnaJ PF00226.26 EIW66930.1 - 4e-24 84.1 0.3 7.2e-24 83.3 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EIW66930.1 - 4.4e-12 46.2 1.4 4.7e-06 26.8 0.1 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1977) Telomere_Sde2 PF13019.1 EIW66931.1 - 1.8e-32 112.3 0.4 1.8e-32 112.3 0.3 2.3 2 2 0 2 2 2 1 Telomere stability and silencing PAN_1 PF00024.21 EIW66932.1 - 0.00049 19.7 0.0 0.00086 19.0 0.0 1.4 1 0 0 1 1 1 1 PAN domain RNA_pol_Rpb2_6 PF00562.23 EIW66933.1 - 3.8e-29 101.6 0.1 4.1e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 EIW66933.1 - 7.2e-10 38.9 0.1 1.1e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Zip PF02535.17 EIW66934.1 - 0.47 9.4 2.1 2.8 6.8 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Yippee-Mis18 PF03226.9 EIW66935.1 - 5.8e-17 61.5 0.2 7.9e-17 61.0 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EIW66935.1 - 0.045 13.6 1.0 0.23 11.3 0.7 1.9 1 1 0 1 1 1 0 C-terminal domain of RIG-I CpXC PF14353.1 EIW66935.1 - 0.052 13.5 0.1 0.92 9.4 0.1 2.0 2 0 0 2 2 2 0 CpXC protein Pacs-1 PF10254.4 EIW66935.1 - 0.13 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein GDPD PF03009.12 EIW66936.1 - 2.9e-34 118.7 0.0 4.7e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EIW66936.1 - 2.1e-07 30.9 0.1 1.6e-05 24.8 0.0 2.9 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family p31comet PF06581.7 EIW66937.1 - 0.021 13.6 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding DUF2587 PF10759.4 EIW66939.1 - 0.061 12.7 0.1 0.15 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW66940.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66940.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66940.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) RNA_pol_Rpo13 PF12136.3 EIW66942.1 - 0.054 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain BATS PF06968.8 EIW66943.1 - 1.7e-28 98.3 0.1 5.7e-28 96.5 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EIW66943.1 - 5e-16 59.3 0.1 1.2e-15 58.0 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily E1_DerP2_DerF2 PF02221.10 EIW66945.1 - 0.042 14.0 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 ML domain RED_N PF07808.8 EIW66946.1 - 8.4e-18 64.4 12.6 8.4e-18 64.4 8.8 2.9 3 0 0 3 3 3 1 RED-like protein N-terminal region Aldedh PF00171.17 EIW66947.1 - 8.8e-183 607.8 0.0 1.1e-182 607.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW66947.1 - 0.00066 18.5 0.0 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EIW66947.1 - 0.095 11.9 0.0 7.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DAO PF01266.19 EIW66948.1 - 8.4e-37 126.8 0.4 1.8e-36 125.8 0.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 EIW66948.1 - 2.8e-13 49.2 0.1 5.6e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EIW66948.1 - 1.7e-07 31.5 0.5 0.0022 18.0 0.1 2.5 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW66948.1 - 2e-06 26.9 0.7 2e-06 26.9 0.5 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW66948.1 - 2.9e-06 27.2 0.0 0.00035 20.5 0.6 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW66948.1 - 4.6e-06 26.5 1.6 6.9e-06 25.9 0.2 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIW66948.1 - 5e-06 25.2 1.6 0.00029 19.4 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.14 EIW66948.1 - 3.7e-05 22.9 3.1 0.00033 19.8 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EIW66948.1 - 5.8e-05 22.3 0.6 0.00011 21.3 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EIW66948.1 - 0.0004 20.7 1.6 0.0012 19.2 1.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW66948.1 - 0.00055 18.9 3.2 0.00056 18.8 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EIW66948.1 - 0.00089 18.2 0.6 0.0046 15.9 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EIW66948.1 - 0.0021 17.2 4.8 0.0069 15.5 3.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Rieske_2 PF13806.1 EIW66948.1 - 0.0032 17.1 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Trp_halogenase PF04820.9 EIW66948.1 - 0.004 15.8 0.5 0.0071 15.0 0.3 1.3 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EIW66948.1 - 0.0063 16.2 0.6 1.4 8.6 0.1 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding EDR1 PF14381.1 EIW66948.1 - 0.038 13.5 0.0 0.12 11.9 0.0 1.8 1 1 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 NAD_binding_7 PF13241.1 EIW66948.1 - 0.068 13.4 0.2 0.23 11.7 0.1 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EIW66948.1 - 0.093 12.8 0.2 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1495 PF07381.6 EIW66951.1 - 0.049 13.3 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) DUF1068 PF06364.7 EIW66952.1 - 0.028 14.0 0.1 0.67 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) DUF1951 PF09188.5 EIW66954.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1951) ABC1 PF03109.11 EIW66956.1 - 3.9e-27 94.6 0.1 8.5e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase_Tyr PF07714.12 EIW66956.1 - 3.5e-05 23.0 0.0 0.0051 15.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW66956.1 - 0.00013 21.7 0.6 0.0078 15.9 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW66956.1 - 0.0088 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.6 EIW66956.1 - 0.072 12.3 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 EIW66956.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase SEP PF08059.8 EIW66959.1 - 2.4e-23 82.2 0.0 6.8e-23 80.7 0.0 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EIW66959.1 - 1.5e-13 50.6 0.3 2.5e-13 49.8 0.2 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EIW66959.1 - 0.00011 21.6 0.1 0.00034 20.0 0.1 1.9 1 1 0 1 1 1 1 UBA-like domain DUF3752 PF12572.3 EIW66960.1 - 8.5e-30 103.8 1.6 8.5e-30 103.8 1.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Nucleoplasmin PF03066.10 EIW66966.1 - 0.61 9.5 17.4 2.3 7.7 3.7 2.6 2 0 0 2 2 2 0 Nucleoplasmin DUF4632 PF15451.1 EIW66966.1 - 2.2 8.2 17.5 6.6 6.7 3.5 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Prothymosin PF03247.9 EIW66966.1 - 3.4 7.8 36.6 1.1 9.4 5.9 4.3 4 0 0 4 4 4 0 Prothymosin/parathymosin family RXT2_N PF08595.6 EIW66966.1 - 4 7.2 10.3 4.7 7.0 0.9 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Miro PF08477.8 EIW66967.1 - 1.5e-33 115.7 0.0 1.8e-20 73.6 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EIW66967.1 - 6.6e-31 105.4 0.2 1.2e-30 104.5 0.2 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EIW66967.1 - 1.4e-28 99.3 0.0 1.3e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_2 PF08356.7 EIW66967.1 - 1.5e-26 91.9 0.0 4.8e-26 90.3 0.0 1.8 2 0 0 2 2 1 1 EF hand associated Arf PF00025.16 EIW66967.1 - 1.2e-10 40.8 0.0 6e-06 25.6 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIW66967.1 - 1.3e-10 41.2 0.0 0.00011 22.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 EIW66967.1 - 1.5e-07 30.1 2.0 0.0033 16.5 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EIW66967.1 - 1.5e-07 31.4 1.0 0.0055 16.8 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIW66967.1 - 6e-07 28.8 0.5 0.004 16.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_22 PF13401.1 EIW66967.1 - 6.5e-06 26.3 0.0 0.18 11.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIW66967.1 - 1.7e-05 24.8 0.5 0.049 13.6 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 EIW66967.1 - 7.4e-05 22.6 5.7 0.43 10.3 0.2 3.2 2 1 1 3 3 3 2 Dynamin family SRPRB PF09439.5 EIW66967.1 - 0.0001 21.6 0.0 0.009 15.2 0.0 2.4 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MobB PF03205.9 EIW66967.1 - 0.00013 21.6 0.2 0.42 10.3 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EIW66967.1 - 0.0005 20.3 1.4 1.2 9.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter NACHT PF05729.7 EIW66967.1 - 0.00072 19.2 0.1 0.28 10.8 0.2 2.6 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 EIW66967.1 - 0.00076 18.7 0.2 0.053 12.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EIW66967.1 - 0.0016 18.7 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW66967.1 - 0.0018 17.7 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EIW66967.1 - 0.0024 17.5 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 EIW66967.1 - 0.0026 17.7 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EIW66967.1 - 0.005 16.4 0.1 2.8 7.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EIW66967.1 - 0.0086 15.5 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 EIW66967.1 - 0.0087 15.5 0.6 0.56 9.6 0.1 2.4 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AIG1 PF04548.11 EIW66967.1 - 0.0099 15.0 0.7 0.013 14.5 0.0 1.6 2 0 0 2 2 1 1 AIG1 family EF-hand_5 PF13202.1 EIW66967.1 - 0.016 14.5 5.8 0.058 12.7 0.6 2.5 2 0 0 2 2 2 0 EF hand RNA_helicase PF00910.17 EIW66967.1 - 0.02 15.0 0.1 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase EF-hand_8 PF13833.1 EIW66967.1 - 0.029 13.9 0.9 6.9 6.3 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair AAA PF00004.24 EIW66967.1 - 0.03 14.5 0.1 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EIW66967.1 - 0.031 13.1 0.2 1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 EIW66967.1 - 0.043 14.1 0.4 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EIW66967.1 - 0.054 12.4 0.2 0.95 8.4 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_10 PF12846.2 EIW66967.1 - 0.064 12.6 0.1 2 7.7 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain G-alpha PF00503.15 EIW66967.1 - 0.065 11.9 0.0 0.77 8.3 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit AAA_5 PF07728.9 EIW66967.1 - 0.065 12.9 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EIW66967.1 - 0.079 12.9 0.1 8.2 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EIW66967.1 - 0.086 12.1 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 EIW66967.1 - 0.098 12.0 0.5 1.7 8.0 0.1 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Guanylate_kin PF00625.16 EIW66967.1 - 0.11 11.8 0.0 0.33 10.3 0.0 1.7 1 0 0 1 1 1 0 Guanylate kinase TrwB_AAD_bind PF10412.4 EIW66967.1 - 0.12 10.9 0.0 3.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.1 EIW66967.1 - 0.14 11.5 0.0 19 4.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_35 PF14516.1 EIW66967.1 - 0.16 10.5 0.0 0.43 9.1 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain SPARC_Ca_bdg PF10591.4 EIW66967.1 - 0.17 11.9 0.1 28 4.7 0.0 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Zeta_toxin PF06414.7 EIW66967.1 - 0.22 10.6 0.0 17 4.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Mito_carr PF00153.22 EIW66968.1 - 1.4e-09 37.4 0.0 0.1 12.3 0.0 4.4 4 1 0 4 4 4 4 Mitochondrial carrier protein 5_nucleotid_C PF02872.13 EIW66969.1 - 1e-22 80.8 0.0 3.4e-21 75.8 0.0 2.4 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EIW66969.1 - 1.5e-09 37.5 0.1 3.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PAT1 PF09770.4 EIW66971.1 - 2.1 6.4 12.0 2.3 6.3 8.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box-like PF12937.2 EIW66973.1 - 9.2e-08 31.6 0.1 3.3e-07 29.9 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW66973.1 - 2.8e-05 23.6 8.1 0.96 9.1 1.8 5.9 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIW66973.1 - 0.00051 19.8 5.1 8.5 6.7 0.1 6.1 5 1 1 6 6 6 1 Leucine Rich repeat DUF1796 PF08795.5 EIW66973.1 - 0.0094 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) LRR_1 PF00560.28 EIW66973.1 - 0.046 13.7 2.2 5 7.5 0.1 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat F-box PF00646.28 EIW66973.1 - 0.33 10.6 8.4 0.44 10.2 2.8 3.2 2 1 0 2 2 2 0 F-box domain FF PF01846.14 EIW66975.1 - 5.1e-31 106.3 16.3 1.3e-09 37.8 0.0 6.2 6 0 0 6 6 6 5 FF domain WW PF00397.21 EIW66975.1 - 5.8e-13 48.4 10.4 2.5e-08 33.6 1.7 2.8 2 0 0 2 2 2 2 WW domain Tim44 PF04280.10 EIW66976.1 - 3.4e-34 117.9 0.8 6.5e-34 117.0 0.0 1.8 2 0 0 2 2 2 1 Tim44-like domain ABM PF03992.11 EIW66977.1 - 0.11 12.5 0.1 0.98 9.5 0.1 2.3 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase PBP1_TM PF14812.1 EIW66977.1 - 1.8 8.9 4.5 4.4 7.6 2.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2587 PF10759.4 EIW66978.1 - 0.044 13.1 0.1 0.12 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PepSY_2 PF13670.1 EIW66978.1 - 0.16 11.8 0.6 0.35 10.8 0.4 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain zf-CCHC PF00098.18 EIW66979.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66979.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66979.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Meiosis_expr PF15163.1 EIW66982.1 - 0.23 11.8 2.3 0.39 11.0 1.6 1.4 1 0 0 1 1 1 0 Meiosis-expressed Cellulase PF00150.13 EIW66983.1 - 7.3e-07 28.6 0.1 1.8e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_72 PF03198.9 EIW66984.1 - 2.8e-96 322.2 0.0 3.7e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EIW66984.1 - 1.2e-18 67.3 1.1 2.3e-18 66.4 0.7 1.5 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EIW66984.1 - 4.7e-05 22.7 0.0 0.0001 21.6 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EIW66984.1 - 0.0024 16.8 0.1 0.0037 16.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain CDK2AP PF09806.4 EIW66984.1 - 1.8 8.7 7.2 3.7 7.7 5.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein EHN PF06441.7 EIW66985.1 - 5.2e-33 113.3 0.1 1e-32 112.3 0.0 1.5 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIW66985.1 - 2.5e-09 37.3 0.0 7.9e-09 35.7 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW66985.1 - 2.4e-05 24.0 0.5 0.0003 20.4 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Cnd1_N PF12922.2 EIW66986.1 - 0.0013 18.3 0.1 0.0017 17.9 0.1 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Vma12 PF11712.3 EIW66986.1 - 0.034 13.8 0.0 0.06 13.0 0.0 1.4 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase EHN PF06441.7 EIW66986.1 - 0.15 12.0 0.8 0.23 11.3 0.2 1.6 2 0 0 2 2 2 0 Epoxide hydrolase N terminus SlyX PF04102.7 EIW66987.1 - 0.08 13.3 0.5 0.19 12.1 0.3 1.5 1 0 0 1 1 1 0 SlyX Asp_protease_2 PF13650.1 EIW66987.1 - 0.14 12.6 0.0 0.42 11.1 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease DUF2587 PF10759.4 EIW66988.1 - 0.045 13.1 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW66989.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW66989.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW66989.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.18 EIW66993.1 - 0.0014 18.4 1.5 0.0029 17.4 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle RFPL3_antisense PF10489.4 EIW66994.1 - 0.11 12.2 0.3 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 Ret finger protein-like 3 antisense IPK PF03770.11 EIW66995.1 - 1.6e-35 122.5 0.0 3e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase SDA1 PF05285.7 EIW66995.1 - 0.07 12.4 7.7 0.11 11.8 5.3 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EIW66995.1 - 0.22 9.4 1.4 0.28 9.1 1.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Osteopontin PF00865.13 EIW66995.1 - 0.62 9.2 12.6 0.99 8.5 8.7 1.2 1 0 0 1 1 1 0 Osteopontin Nop14 PF04147.7 EIW66995.1 - 1.4 6.7 8.3 2.5 5.9 5.8 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EIW66995.1 - 1.4 8.4 5.7 2.3 7.7 4.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Aldedh PF00171.17 EIW66996.1 - 4.8e-169 562.5 0.0 5.4e-169 562.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cu_amine_oxid PF01179.15 EIW66997.1 - 2.9e-104 349.0 0.2 3.7e-104 348.7 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EIW66997.1 - 2.7e-06 27.2 0.0 9.7e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EIW66997.1 - 0.036 14.1 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Copper amine oxidase, N2 domain Gag_spuma PF03276.9 EIW66998.1 - 0.45 8.7 2.8 0.61 8.3 1.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Glucan_synthase PF02364.10 EIW66999.1 - 0 1420.9 0.0 0 1420.9 0.0 1.5 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EIW66999.1 - 4e-39 133.1 0.0 1.2e-38 131.6 0.0 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 HCNGP PF07818.8 EIW67000.1 - 1.3e-20 73.2 0.0 2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein Atrophin-1 PF03154.10 EIW67000.1 - 2.1 6.3 12.2 2.5 6.1 8.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family Mito_carr PF00153.22 EIW67001.1 - 2e-59 197.3 0.2 3.9e-21 74.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2422 PF10337.4 EIW67003.1 - 0.34 9.6 2.6 0.45 9.2 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) KilA-N PF04383.8 EIW67003.1 - 0.67 9.6 5.7 1.8 8.2 1.0 2.5 1 1 2 3 3 3 0 KilA-N domain Apc9 PF12856.2 EIW67004.1 - 0.00092 19.2 0.1 0.044 13.8 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 9 zf-CCHC PF00098.18 EIW67006.1 - 0.0025 17.6 1.9 0.0045 16.8 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Cullin PF00888.17 EIW67008.1 - 1.7e-41 142.4 0.0 2.7e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EIW67008.1 - 1.6e-05 25.0 0.0 4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 O-FucT PF10250.4 EIW67009.1 - 0.00021 20.5 0.0 0.0015 17.7 0.0 2.0 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Grp1_Fun34_YaaH PF01184.14 EIW67010.1 - 9.6e-62 208.0 9.8 2.8e-53 180.3 5.2 2.0 2 0 0 2 2 2 2 GPR1/FUN34/yaaH family HopW1-1 PF15457.1 EIW67011.1 - 0.036 13.0 2.3 0.062 12.3 1.6 1.3 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA LEA_4 PF02987.11 EIW67011.1 - 0.043 13.6 2.9 0.043 13.6 2.0 2.8 3 0 0 3 3 3 0 Late embryogenesis abundant protein Prominin PF05478.6 EIW67011.1 - 0.27 8.7 1.9 0.27 8.7 1.3 1.0 1 0 0 1 1 1 0 Prominin Sec8_exocyst PF04048.9 EIW67011.1 - 0.38 10.3 2.6 0.38 10.3 1.3 1.4 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF883 PF05957.8 EIW67011.1 - 0.62 10.4 6.5 2.3 8.6 3.4 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.8 EIW67011.1 - 0.79 9.7 5.4 1 9.4 3.8 1.2 1 0 0 1 1 1 0 DivIVA protein DDHD PF02862.12 EIW67011.1 - 1 9.0 3.6 1.1 9.0 2.5 1.0 1 0 0 1 1 1 0 DDHD domain Cytochrom_C_2 PF01322.15 EIW67011.1 - 1.6 9.3 6.5 2 8.9 4.5 1.1 1 0 0 1 1 1 0 Cytochrome C' YtxH PF12732.2 EIW67011.1 - 8.6 6.8 12.4 2.4e+02 2.1 8.6 2.3 1 1 0 1 1 1 0 YtxH-like protein Sds3 PF08598.6 EIW67012.1 - 8.8e-13 48.2 9.9 2e-12 47.1 6.8 1.6 1 1 0 1 1 1 1 Sds3-like DUF2413 PF10310.4 EIW67013.1 - 7.2e-61 206.3 0.0 1.2e-60 205.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) DnaJ PF00226.26 EIW67014.1 - 3.1e-20 71.6 0.2 5.3e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4131 PF13567.1 EIW67014.1 - 0.039 13.3 0.0 0.093 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Med5 PF08689.5 EIW67015.1 - 4.9e-16 57.6 0.2 1.1e-15 56.4 0.1 1.6 2 0 0 2 2 2 1 Mediator complex subunit Med5 Pkinase PF00069.20 EIW67016.1 - 4.6e-57 193.1 0.0 5.7e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67016.1 - 3.3e-34 118.1 0.0 3.9e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW67016.1 - 0.00012 21.8 0.1 0.0012 18.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW67016.1 - 0.0052 15.7 0.0 0.016 14.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIW67016.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EIW67016.1 - 0.044 12.5 0.1 0.063 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Hist_deacetyl PF00850.14 EIW67017.1 - 1.1e-81 274.5 0.1 1.6e-81 273.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain BCAS2 PF05700.6 EIW67018.1 - 3.8e-54 183.4 0.3 4.2e-54 183.3 0.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) SPAM PF02090.10 EIW67018.1 - 0.0031 17.5 0.9 0.0069 16.3 0.2 1.7 1 1 1 2 2 2 1 Salmonella surface presentation of antigen gene type M protein DivIC PF04977.10 EIW67018.1 - 0.005 16.2 0.3 2.5 7.6 0.0 2.4 2 0 0 2 2 2 2 Septum formation initiator Spectrin PF00435.16 EIW67018.1 - 0.023 14.9 1.2 0.068 13.4 0.4 2.1 1 1 1 2 2 2 0 Spectrin repeat DUF4618 PF15397.1 EIW67018.1 - 0.044 13.1 0.7 0.14 11.4 0.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Enkurin PF13864.1 EIW67018.1 - 0.46 10.7 2.4 0.85 9.8 0.5 2.2 3 0 0 3 3 3 0 Calmodulin-binding ATP-synt_F PF01990.12 EIW67019.1 - 6.4e-31 106.5 0.1 7.4e-31 106.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 EIW67019.1 - 0.043 12.7 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF2953 PF11167.3 EIW67020.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) Tropomyosin_1 PF12718.2 EIW67021.1 - 5.1e-40 136.6 32.3 6.4e-40 136.3 22.4 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EIW67021.1 - 1.1e-10 40.9 33.2 4.5e-05 22.6 8.6 3.5 1 1 2 3 3 3 3 Tropomyosin GAS PF13851.1 EIW67021.1 - 0.0014 17.8 28.8 0.021 14.0 7.7 2.9 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF869 PF05911.6 EIW67021.1 - 0.0018 16.5 9.5 0.0018 16.5 6.6 2.0 1 1 1 2 2 2 1 Plant protein of unknown function (DUF869) Phage_GP20 PF06810.6 EIW67021.1 - 0.0035 16.7 8.6 0.0035 16.7 6.0 2.3 1 1 1 2 2 2 1 Phage minor structural protein GP20 Cast PF10174.4 EIW67021.1 - 0.0059 14.7 30.0 0.0068 14.5 20.8 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Clr5 PF14420.1 EIW67021.1 - 0.014 15.2 0.6 0.035 13.9 0.4 1.6 1 0 0 1 1 1 0 Clr5 domain CENP-F_leu_zip PF10473.4 EIW67021.1 - 0.017 14.9 8.4 0.017 14.9 5.8 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.1 EIW67021.1 - 0.049 13.5 29.7 0.76 9.7 7.8 3.2 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 DUF4201 PF13870.1 EIW67021.1 - 0.071 12.5 25.1 0.12 11.8 5.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Lectin_N PF03954.9 EIW67021.1 - 0.12 11.7 10.1 0.19 11.1 4.7 2.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain IZUMO PF15005.1 EIW67021.1 - 0.14 12.2 6.2 0.17 11.9 4.3 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion DUF3450 PF11932.3 EIW67021.1 - 0.15 11.3 19.6 0.62 9.2 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3584 PF12128.3 EIW67021.1 - 0.19 8.9 29.8 0.3 8.3 20.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.14 EIW67021.1 - 0.22 11.0 33.5 0.25 10.8 9.8 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.3 EIW67021.1 - 0.24 11.2 35.4 0.86 9.4 5.6 3.4 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 EIW67021.1 - 0.25 11.0 17.6 1.6 8.5 3.9 2.3 1 1 1 2 2 2 0 Laminin Domain II APG6 PF04111.7 EIW67021.1 - 0.41 9.6 32.0 0.15 11.0 14.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 AF0941-like PF14591.1 EIW67021.1 - 0.61 10.1 16.3 0.65 10.0 3.3 2.3 1 1 1 2 2 2 0 AF0941-like SlyX PF04102.7 EIW67021.1 - 0.68 10.3 22.6 0.073 13.4 5.1 3.6 2 2 2 4 4 4 0 SlyX Lebercilin PF15619.1 EIW67021.1 - 0.75 9.1 30.5 2.3 7.6 14.6 2.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.3 EIW67021.1 - 0.77 9.6 27.9 5.1 6.9 7.8 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 EIW67021.1 - 0.89 9.0 24.0 0.58 9.6 5.4 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Borrelia_P83 PF05262.6 EIW67021.1 - 0.91 7.7 24.1 1 7.5 16.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Reo_sigmaC PF04582.7 EIW67021.1 - 0.98 8.5 4.5 5.2 6.1 0.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EIW67021.1 - 1 9.1 15.0 0.49 10.1 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Mod_r PF07200.8 EIW67021.1 - 1.1 9.1 24.4 0.6 10.0 11.4 2.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein COG2 PF06148.6 EIW67021.1 - 1.2 9.0 18.6 3.6 7.4 5.7 2.2 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 EIW67021.1 - 1.2 8.7 30.0 4.7 6.7 20.8 1.8 1 1 0 1 1 1 0 IncA protein LRS4 PF10422.4 EIW67021.1 - 1.2 8.4 16.5 1.5 8.1 11.4 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF4200 PF13863.1 EIW67021.1 - 2 8.3 33.2 1.5 8.7 7.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 EIW67021.1 - 2.1 8.1 29.3 4.5 7.0 14.3 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.15 EIW67021.1 - 2.2 8.0 29.9 0.93 9.2 11.4 3.8 1 1 3 4 4 4 0 Prefoldin subunit NPV_P10 PF05531.7 EIW67021.1 - 2.5 8.4 11.5 9 6.6 2.4 3.1 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Vps5 PF09325.5 EIW67021.1 - 3.1 6.9 21.2 1.3 8.2 5.7 2.3 1 1 0 2 2 2 0 Vps5 C terminal like FliD_C PF07195.7 EIW67021.1 - 3.2 6.9 13.5 3.7 6.7 2.9 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF4407 PF14362.1 EIW67021.1 - 3.3 6.5 18.7 4.5 6.1 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 EIW67021.1 - 3.5 5.9 20.6 8.4 4.7 14.1 1.5 1 1 0 1 1 1 0 AAA domain FemAB PF02388.11 EIW67021.1 - 3.6 6.1 21.0 0.1 11.2 4.6 2.0 1 1 1 2 2 2 0 FemAB family DUF812 PF05667.6 EIW67021.1 - 3.9 5.8 24.6 28 3.0 17.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF3391 PF11871.3 EIW67021.1 - 4 7.6 17.7 4.3 7.5 4.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) Seryl_tRNA_N PF02403.17 EIW67021.1 - 4.1 7.4 26.7 1.8 8.6 12.6 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.1 EIW67021.1 - 4.1 7.7 18.2 0.77 10.1 2.9 2.6 2 1 0 2 2 2 0 Snapin/Pallidin DUF3287 PF11690.3 EIW67021.1 - 4.2 7.4 9.7 1.2 9.2 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) LIN37 PF15306.1 EIW67021.1 - 4.5 7.2 14.5 11 5.9 10.0 1.7 1 1 0 1 1 1 0 LIN37 Uds1 PF15456.1 EIW67021.1 - 4.9 7.1 24.1 8.6 6.3 11.0 3.0 1 1 2 3 3 3 0 Up-regulated During Septation HlyD PF00529.15 EIW67021.1 - 5 6.3 19.0 6.8 5.8 13.2 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF2422 PF10337.4 EIW67021.1 - 5.2 5.7 5.7 7 5.3 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF948 PF06103.6 EIW67021.1 - 5.2 7.0 7.9 1.1 9.1 1.2 2.5 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Imm42 PF15601.1 EIW67021.1 - 5.8 6.3 7.6 1.7 8.0 1.0 2.4 1 1 1 2 2 2 0 Immunity protein 42 V_ATPase_I PF01496.14 EIW67021.1 - 5.9 4.6 19.7 7 4.3 12.8 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 EIW67021.1 - 6.2 6.5 25.9 4.4 7.0 6.2 2.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) FliJ PF02050.11 EIW67021.1 - 6.5 6.8 27.9 5.7 7.0 4.1 3.7 1 1 2 4 4 4 0 Flagellar FliJ protein AAA_27 PF13514.1 EIW67021.1 - 7.1 4.1 29.2 15 3.1 20.2 1.5 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.6 EIW67021.1 - 7.6 5.0 24.7 7.1 5.1 5.9 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein HisKA_3 PF07730.8 EIW67021.1 - 7.9 6.9 14.6 19 5.6 3.8 3.8 1 1 2 3 3 3 0 Histidine kinase DUF342 PF03961.8 EIW67021.1 - 7.9 4.7 18.6 1.3 7.3 3.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) WXG100 PF06013.7 EIW67021.1 - 8.4 6.4 12.9 12 5.9 0.8 3.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Sugarporin_N PF11471.3 EIW67021.1 - 8.9 6.0 22.4 0.69 9.6 2.1 3.6 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension IL22 PF14565.1 EIW67022.1 - 0.018 15.1 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Velvet PF11754.3 EIW67023.1 - 5e-25 88.3 0.0 9.5e-25 87.3 0.0 1.4 1 1 0 1 1 1 1 Velvet factor SAP PF02037.22 EIW67024.1 - 0.082 12.4 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 SAP domain DDE_1 PF03184.14 EIW67026.1 - 4.2e-39 133.9 0.0 1e-38 132.6 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW67026.1 - 7e-10 38.5 0.0 1.8e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EIW67026.1 - 0.00019 21.2 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Inhibitor_I42 PF09394.5 EIW67028.1 - 0.0097 16.2 1.3 0.32 11.3 0.1 2.8 2 1 0 2 2 2 1 Chagasin family peptidase inhibitor I42 DUF1191 PF06697.7 EIW67028.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 EIW67028.1 - 0.049 11.9 0.0 0.073 11.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 EIW67028.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Beta-APP PF03494.8 EIW67028.1 - 0.16 11.4 0.8 0.34 10.3 0.6 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF1180 PF06679.7 EIW67028.1 - 0.17 11.7 2.3 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) adh_short PF00106.20 EIW67029.1 - 8.9e-11 41.9 0.5 1.4e-10 41.3 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW67029.1 - 0.00043 19.9 0.6 0.00078 19.1 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW67029.1 - 0.0031 17.3 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EIW67029.1 - 0.0038 16.8 0.1 0.0057 16.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MoCF_biosynth PF00994.19 EIW67029.1 - 0.011 15.0 0.0 0.024 14.0 0.0 1.6 1 1 0 1 1 1 0 Probable molybdopterin binding domain Epimerase PF01370.16 EIW67029.1 - 0.017 14.5 0.2 0.025 14.0 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW67029.1 - 0.018 15.0 0.3 0.043 13.8 0.2 1.6 2 0 0 2 2 2 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EIW67029.1 - 0.039 13.0 0.2 0.086 11.9 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TIR-like PF10137.4 EIW67029.1 - 0.057 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Polysacc_synt_2 PF02719.10 EIW67029.1 - 0.084 11.7 0.0 0.16 10.8 0.1 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Glyco_transf_9 PF01075.12 EIW67029.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Pkinase PF00069.20 EIW67031.1 - 1.6e-59 201.1 0.0 1.9e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67031.1 - 7.5e-18 64.5 0.0 1.1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW67031.1 - 8e-09 35.5 0.0 2e-06 27.7 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW67031.1 - 0.0059 16.2 0.1 0.0059 16.2 0.0 1.8 2 1 0 2 2 2 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EIW67031.1 - 0.012 15.0 1.3 3.1 7.0 0.0 2.8 3 1 0 3 3 3 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EIW67031.1 - 0.032 13.1 0.0 0.073 12.0 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EIW67031.1 - 0.066 12.2 0.2 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGAP PF00620.22 EIW67032.1 - 3.2e-33 114.5 1.3 4.2e-32 110.8 0.1 2.8 2 1 0 2 2 2 1 RhoGAP domain Acetyltransf_1 PF00583.19 EIW67032.1 - 2.5e-11 43.4 0.0 7.5e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW67032.1 - 2.5e-08 33.9 0.0 6.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FCH PF00611.18 EIW67032.1 - 1.5e-06 28.3 0.1 4.8e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Acetyltransf_10 PF13673.1 EIW67032.1 - 0.00034 20.7 0.0 0.0028 17.7 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CorC_HlyC PF03471.12 EIW67032.1 - 0.0086 15.8 0.0 2.7 7.8 0.0 2.6 2 0 0 2 2 2 1 Transporter associated domain Acetyltransf_9 PF13527.1 EIW67032.1 - 0.025 14.4 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW67032.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lipase_3 PF01764.20 EIW67033.1 - 6.4e-20 71.2 0.0 3.5e-16 59.0 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EIW67033.1 - 0.00042 20.2 1.5 0.11 12.3 0.2 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW67033.1 - 0.14 11.9 1.0 3.5 7.3 0.1 2.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family NT5C PF06941.7 EIW67034.1 - 5.1e-13 48.9 0.8 2.5e-12 46.7 0.0 2.2 3 0 0 3 3 3 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase PF00702.21 EIW67034.1 - 5e-05 23.8 0.3 0.00037 20.9 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase LNS2 PF08235.8 EIW67034.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) HAD_2 PF13419.1 EIW67034.1 - 0.0084 16.3 0.1 0.077 13.2 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EIW67034.1 - 0.015 15.1 0.0 0.12 12.3 0.0 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EIW67034.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF866 PF05907.8 EIW67035.1 - 3e-38 130.8 0.2 3.4e-38 130.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF3776 PF12618.3 EIW67035.1 - 0.0028 18.2 0.0 0.0036 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3776) zinc_ribbon_6 PF14599.1 EIW67035.1 - 0.03 14.1 0.3 13 5.6 0.0 3.2 3 0 0 3 3 3 0 Zinc-ribbon DUF3716 PF12511.3 EIW67035.1 - 0.042 13.4 1.5 0.069 12.7 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) PHD PF00628.24 EIW67035.1 - 0.051 13.2 1.0 0.087 12.5 0.7 1.4 1 0 0 1 1 1 0 PHD-finger SH3_2 PF07653.12 EIW67035.1 - 0.19 11.2 1.1 0.42 10.1 0.0 2.0 3 0 0 3 3 3 0 Variant SH3 domain tRNA-synt_2c PF01411.14 EIW67036.1 - 1.7e-206 686.7 0.0 2.2e-206 686.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EIW67036.1 - 9.8e-18 63.7 0.3 2.7e-17 62.3 0.2 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EIW67036.1 - 1.3e-09 37.5 0.6 4.3e-09 35.9 0.4 2.0 1 0 0 1 1 1 1 DHHA1 domain RhoGAP PF00620.22 EIW67038.1 - 1.8e-37 128.2 0.1 3.4e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EIW67038.1 - 3.1e-26 91.1 42.2 2e-11 43.7 6.2 4.6 4 0 0 4 4 4 4 LIM domain EAP30 PF04157.11 EIW67039.1 - 2e-51 174.2 0.1 2.4e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF4423 PF14394.1 EIW67039.1 - 0.022 14.3 0.0 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) MitMem_reg PF13012.1 EIW67039.1 - 0.03 14.4 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function OPT PF03169.10 EIW67040.1 - 1.8e-153 512.2 26.9 2.1e-153 512.0 18.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NUP PF06516.6 EIW67041.1 - 7.7e-109 363.3 0.0 8.8e-109 363.1 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) TFIID_30kDa PF03540.8 EIW67043.1 - 2.2e-24 84.9 0.0 3.1e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 EIW67043.1 - 0.00011 21.7 0.1 0.0016 18.1 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated DUF1771 PF08590.5 EIW67044.1 - 3.8e-16 58.8 5.5 7.3e-16 57.9 3.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 EIW67044.1 - 1.5e-09 37.3 10.4 2.5e-05 23.8 1.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 EIW67044.1 - 2.2e-07 30.9 0.0 5.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Smr domain zf-C3H1 PF10650.4 EIW67044.1 - 0.094 12.2 4.9 0.32 10.5 0.1 2.7 3 0 0 3 3 3 0 Putative zinc-finger domain CBFD_NFYB_HMF PF00808.18 EIW67045.1 - 4.5e-21 74.6 0.4 6.8e-21 74.0 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIW67045.1 - 4.1e-14 52.4 0.1 6.4e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Mito_fiss_reg PF05308.6 EIW67045.1 - 0.061 12.6 9.6 0.015 14.6 2.4 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator CENP-X PF09415.5 EIW67045.1 - 0.086 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Aminotran_1_2 PF00155.16 EIW67046.1 - 4.7e-23 81.7 0.0 5.9e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EIW67046.1 - 6.7e-07 28.2 0.0 1.3e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Nucleoplasmin PF03066.10 EIW67047.1 - 0.13 11.7 11.8 0.26 10.8 8.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EIW67047.1 - 0.14 11.4 4.2 0.26 10.5 2.9 1.3 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 EIW67047.1 - 2.8 7.0 11.5 7.7 5.5 8.0 1.7 1 0 0 1 1 1 0 Myc amino-terminal region DZR PF12773.2 EIW67049.1 - 0.0067 16.2 1.4 0.0067 16.2 1.0 2.1 2 0 0 2 2 2 1 Double zinc ribbon Toxin_13 PF07822.6 EIW67049.1 - 0.048 13.5 3.0 0.11 12.4 2.0 1.5 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein RAI1 PF08652.6 EIW67052.1 - 1.2e-21 76.1 0.0 2.6e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease MBOAT PF03062.14 EIW67053.1 - 2.9e-32 112.1 13.4 2.9e-32 112.1 9.3 2.0 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EIW67053.1 - 3.6e-06 26.9 2.2 3.6e-06 26.9 1.5 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Fork_head PF00250.13 EIW67054.1 - 9.4e-16 57.6 0.0 1.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Fork head domain Rad10 PF03834.9 EIW67055.1 - 6.1e-25 86.7 0.3 1.3e-24 85.6 0.1 1.6 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EIW67055.1 - 4.7e-07 29.8 0.1 1.3e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EIW67055.1 - 2.2e-05 24.2 0.7 0.00042 20.1 0.0 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix motif PARP_regulatory PF01358.13 EIW67055.1 - 0.014 14.0 0.1 0.019 13.6 0.1 1.3 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit TarH PF02203.10 EIW67055.1 - 0.041 13.7 0.2 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue 4HB_MCP_1 PF12729.2 EIW67055.1 - 0.13 11.5 1.4 0.25 10.6 1.0 1.4 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF3928 PF13065.1 EIW67055.1 - 0.13 12.5 0.9 1 9.6 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3928) DUF1365 PF07103.6 EIW67056.1 - 7.1e-39 133.3 0.1 1.6e-38 132.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1365) S10_plectin PF03501.10 EIW67057.1 - 7.2e-41 137.9 0.1 8.5e-41 137.7 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain SKN1 PF03935.10 EIW67058.1 - 1.1e-158 528.5 6.7 1.2e-158 528.4 4.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) HTH_3 PF01381.17 EIW67059.1 - 0.075 12.8 0.0 0.26 11.1 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix Sds3 PF08598.6 EIW67063.1 - 5.4e-08 32.6 4.2 5.4e-08 32.6 2.9 2.1 1 1 1 2 2 2 1 Sds3-like Got1 PF04178.7 EIW67064.1 - 2.3e-30 105.1 13.1 3.1e-30 104.7 9.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family ABC2_membrane_4 PF12730.2 EIW67064.1 - 5 6.2 21.6 0.66 9.1 5.0 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein Syntaxin-18_N PF10496.4 EIW67065.1 - 1.5e-18 66.4 1.6 6.3e-18 64.3 0.3 2.6 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus GOLGA2L5 PF15070.1 EIW67065.1 - 1.5e-05 23.7 5.0 2.7e-05 22.9 3.5 1.3 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 SNARE PF05739.14 EIW67065.1 - 0.0052 16.4 0.5 0.013 15.1 0.3 1.8 1 1 0 1 1 1 1 SNARE domain SNARE_assoc PF09335.6 EIW67066.1 - 2.3e-08 34.2 5.1 2.3e-08 34.2 3.6 2.1 2 1 0 2 2 2 1 SNARE associated Golgi protein WD40 PF00400.27 EIW67067.1 - 1.2e-41 139.1 2.2 2.8e-09 36.5 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Me-amine-dh_H PF06433.6 EIW67067.1 - 0.11 11.1 0.0 1.1 7.7 0.0 2.1 1 1 1 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) zf-HIT PF04438.11 EIW67068.1 - 6.8e-10 38.4 10.3 1e-09 37.8 7.2 1.3 1 0 0 1 1 1 1 HIT zinc finger vWA-TerF-like PF10138.4 EIW67068.1 - 0.043 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus zf-MYND PF01753.13 EIW67068.1 - 0.57 10.0 10.1 1.1 9.1 7.0 1.5 1 0 0 1 1 1 0 MYND finger Tnp_zf-ribbon_2 PF13842.1 EIW67068.1 - 1.8 9.0 9.4 3.2 8.2 6.5 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-AN1 PF01428.11 EIW67068.1 - 2.3 8.1 8.4 4.6 7.2 5.8 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger zf-C2H2_6 PF13912.1 EIW67068.1 - 2.3 8.2 9.3 0.41 10.6 1.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Ferrochelatase PF00762.14 EIW67069.1 - 5.8e-99 331.0 0.0 6.8e-99 330.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Exonuc_V_gamma PF04257.9 EIW67069.1 - 0.19 9.6 0.0 0.27 9.1 0.0 1.2 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit Nup188 PF10487.4 EIW67070.1 - 5.2e-12 44.5 0.1 3.6e-10 38.4 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 ACC_central PF08326.7 EIW67071.1 - 2.8e-219 729.8 3.0 3.4e-219 729.5 2.1 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EIW67071.1 - 2.1e-151 504.6 0.0 2.8e-151 504.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EIW67071.1 - 4.3e-52 176.4 0.0 1e-51 175.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EIW67071.1 - 2.6e-25 88.6 0.0 5.6e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIW67071.1 - 4.6e-21 74.8 0.0 1.7e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EIW67071.1 - 1.6e-14 53.2 0.0 3.5e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EIW67071.1 - 5e-12 45.9 0.0 2.2e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIW67071.1 - 1.8e-08 33.5 0.0 0.0019 16.9 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EIW67071.1 - 0.0012 18.6 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIW67071.1 - 0.0022 17.4 0.0 0.0078 15.6 0.0 2.0 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EIW67071.1 - 0.0063 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EIW67071.1 - 0.014 14.8 0.0 0.086 12.3 0.0 2.2 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Enkurin PF13864.1 EIW67071.1 - 0.023 14.8 0.4 0.084 13.0 0.3 2.0 1 0 0 1 1 1 0 Calmodulin-binding WD40 PF00400.27 EIW67072.1 - 0.0038 17.0 11.0 0.012 15.4 0.1 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIW67072.1 - 0.011 14.4 0.1 0.25 10.0 0.0 2.4 3 0 0 3 3 3 0 Nup133 N terminal like Mob1_phocein PF03637.12 EIW67075.1 - 4.4e-59 199.0 0.7 5e-59 198.8 0.5 1.0 1 0 0 1 1 1 1 Mob1/phocein family RasGAP PF00616.14 EIW67076.1 - 2e-41 141.8 0.1 3.9e-40 137.6 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EIW67076.1 - 1.6e-07 31.3 0.0 5.1e-07 29.6 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Peripla_BP_6 PF13458.1 EIW67076.1 - 0.0017 17.7 0.1 0.0037 16.6 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein Ribosomal_L28e PF01778.12 EIW67077.1 - 1.1e-31 109.6 1.5 1.1e-31 109.6 1.1 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EIW67077.1 - 3.9e-22 78.2 18.8 3.9e-22 78.2 13.1 2.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region Nop14 PF04147.7 EIW67077.1 - 0.46 8.3 23.3 0.56 8.0 16.1 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4375 PF14300.1 EIW67077.1 - 9.4 6.2 9.1 8.9 6.3 4.4 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4375) DUF1640 PF07798.6 EIW67078.1 - 2.3e-63 213.4 9.1 2.6e-63 213.2 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Exonuc_VII_L PF02601.10 EIW67078.1 - 0.0018 17.5 4.0 0.0025 17.0 2.7 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit HALZ PF02183.13 EIW67078.1 - 0.11 12.2 2.2 0.23 11.2 0.3 2.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF2115 PF09888.4 EIW67078.1 - 0.44 10.6 3.4 0.59 10.2 2.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) FlaC_arch PF05377.6 EIW67078.1 - 0.92 9.4 5.6 4.9 7.1 0.9 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Phage_lysis PF03245.8 EIW67078.1 - 2.8 7.9 9.5 14 5.7 6.6 2.0 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein Acyltransferase PF01553.16 EIW67079.1 - 3.3e-17 62.1 0.0 4.8e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase BCL9 PF11502.3 EIW67079.1 - 0.026 14.0 0.6 5.4 6.6 0.1 2.4 2 0 0 2 2 2 0 B-cell lymphoma 9 protein SPC25 PF06703.6 EIW67079.1 - 0.094 12.2 0.2 0.22 11.1 0.1 1.7 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) APH PF01636.18 EIW67082.1 - 0.0001 22.1 0.2 0.0087 15.8 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-AN1 PF01428.11 EIW67082.1 - 0.0036 17.1 5.5 0.0067 16.2 3.8 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger zf-C2HC5 PF06221.8 EIW67082.1 - 0.049 13.4 1.9 0.089 12.5 1.3 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Polysacc_deac_1 PF01522.16 EIW67083.1 - 4.9e-28 97.2 0.0 8.8e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIW67083.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Ribosomal_L35Ae PF01247.13 EIW67084.1 - 1e-39 134.1 1.0 1.3e-39 133.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EIW67084.1 - 3.5e-06 26.8 0.0 0.061 13.2 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Zds_C PF08632.5 EIW67085.1 - 2e-21 75.1 0.3 3.5e-21 74.3 0.2 1.3 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term OPT PF03169.10 EIW67086.1 - 9.4e-127 424.0 43.0 1.1e-124 417.2 29.8 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Proteasome PF00227.21 EIW67087.1 - 3e-51 173.3 0.1 4.3e-46 156.5 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EIW67087.1 - 1.2e-14 53.2 0.2 2.1e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF837 PF05769.6 EIW67088.1 - 1.6e-05 24.5 5.4 0.00071 19.1 0.7 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF837) Corona_S2 PF01601.11 EIW67088.1 - 0.029 12.4 0.3 0.041 11.9 0.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Herpes_BLRF2 PF05812.7 EIW67088.1 - 0.05 13.4 5.6 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein TMV_coat PF00721.16 EIW67088.1 - 0.09 12.7 0.4 0.27 11.1 0.3 1.9 1 1 0 1 1 1 0 Virus coat protein (TMV like) ATP-synt_B PF00430.13 EIW67088.1 - 2.5 7.9 7.9 5 6.9 1.6 2.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) PI3_PI4_kinase PF00454.22 EIW67089.1 - 1.5e-43 148.9 0.3 2.9e-43 148.0 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EIW67089.1 - 2.4e-27 95.5 0.1 6.8e-27 94.1 0.0 1.8 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EIW67089.1 - 2.3e-11 42.9 0.2 9.6e-11 40.9 0.1 2.2 1 0 0 1 1 1 1 FATC domain TarH PF02203.10 EIW67089.1 - 0.023 14.5 1.9 0.075 12.8 1.3 1.8 1 0 0 1 1 1 0 Tar ligand binding domain homologue TPR_16 PF13432.1 EIW67091.1 - 2.9e-11 43.7 0.0 4.3e-05 24.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW67091.1 - 3.5e-10 40.0 0.2 0.00058 20.1 0.0 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIW67091.1 - 5.3e-09 35.6 0.1 0.042 13.5 0.0 4.0 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 EIW67091.1 - 1e-07 31.5 0.0 0.0019 18.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW67091.1 - 2.7e-07 30.6 1.3 0.0025 18.2 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIW67091.1 - 0.00022 20.8 2.1 0.087 12.7 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW67091.1 - 0.0003 20.2 0.6 0.15 11.7 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIW67091.1 - 0.00046 20.2 0.0 0.8 9.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW67091.1 - 0.0024 17.5 1.2 12 6.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PsaA_PsaB PF00223.14 EIW67091.1 - 0.032 12.3 0.0 0.043 11.8 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein TPR_15 PF13429.1 EIW67091.1 - 0.036 13.1 0.0 5.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW67091.1 - 0.06 13.1 0.2 6.1 6.8 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW67091.1 - 0.92 10.1 3.9 5.2 7.7 0.0 3.9 6 0 0 6 6 4 0 Tetratricopeptide repeat Proteasome PF00227.21 EIW67092.1 - 6e-50 169.1 0.2 7.5e-50 168.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit PSDC PF12588.3 EIW67094.1 - 0.023 14.3 0.1 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Phophatidylserine decarboxylase vATP-synt_E PF01991.13 EIW67094.1 - 0.042 13.1 0.9 0.065 12.5 0.6 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ATG_C PF09333.6 EIW67094.1 - 0.044 13.9 0.7 0.13 12.3 0.2 1.9 1 1 1 2 2 2 0 ATG C terminal domain DUF4199 PF13858.1 EIW67094.1 - 0.067 13.1 0.2 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) PgaD PF13994.1 EIW67095.1 - 0.072 12.5 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein PIG-S PF10510.4 EIW67097.1 - 1.9e-113 379.8 0.0 1.9e-113 379.8 0.0 1.9 2 1 1 3 3 3 1 Phosphatidylinositol-glycan biosynthesis class S protein THOC7 PF05615.8 EIW67097.1 - 6.7e-09 36.1 8.3 6.7e-09 36.1 5.8 1.9 2 0 0 2 2 2 1 Tho complex subunit 7 IncA PF04156.9 EIW67097.1 - 0.29 10.7 13.4 0.56 9.7 9.3 1.4 1 0 0 1 1 1 0 IncA protein FUSC PF04632.7 EIW67097.1 - 0.52 8.6 2.4 0.71 8.2 1.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_13 PF13166.1 EIW67097.1 - 1.2 7.4 8.6 1.7 6.9 6.0 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EIW67097.1 - 2.8 5.7 5.4 4.6 4.9 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family He_PIG PF05345.7 EIW67099.1 - 7.5e-09 35.4 25.8 0.00027 20.9 3.0 5.2 5 0 0 5 5 5 4 Putative Ig domain VPEP PF07589.6 EIW67099.1 - 1.1 9.2 7.8 2.1 8.3 5.4 1.5 1 0 0 1 1 1 0 PEP-CTERM motif WD40 PF00400.27 EIW67100.1 - 1.1e-56 186.8 21.7 8.9e-09 34.9 0.0 8.7 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EIW67100.1 - 9.4e-12 44.4 0.3 2.9e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 EIW67100.1 - 2e-10 39.4 7.4 0.16 10.0 0.0 5.1 3 2 2 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.28 EIW67100.1 - 4.8e-09 35.6 0.2 2.9e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 F-box domain CKS PF01111.14 EIW67102.1 - 2.6e-30 104.0 0.1 3.1e-30 103.7 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ribosomal_60s PF00428.14 EIW67103.1 - 1.2e-28 99.3 6.6 1.3e-28 99.1 4.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S5_C PF03719.10 EIW67105.1 - 1.3e-12 46.8 0.2 3.2e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EIW67105.1 - 1.5e-05 24.6 0.3 3.2e-05 23.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain UQ_con PF00179.21 EIW67106.1 - 1.3e-23 82.9 0.0 1.9e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Fungal_trans PF04082.13 EIW67108.1 - 1.5e-08 33.8 0.2 2.8e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW67108.1 - 6.2e-07 29.2 8.4 1e-06 28.5 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CTD PF12815.2 EIW67108.1 - 0.0029 18.0 4.8 0.0029 18.0 3.3 2.4 2 0 0 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Mito_fiss_reg PF05308.6 EIW67109.1 - 0.015 14.6 2.5 0.015 14.6 1.7 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.14 EIW67109.1 - 7 5.8 10.2 0.5 9.6 3.6 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF1752 PF08550.5 EIW67110.1 - 2.8e-10 39.5 4.2 4.9e-10 38.8 2.9 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RINGv PF12906.2 EIW67111.1 - 2.1e-11 43.7 4.6 3.2e-11 43.0 3.2 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EIW67111.1 - 0.00053 19.7 4.8 0.00083 19.1 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain V-ATPase_G PF03179.10 EIW67112.1 - 7e-31 106.6 11.5 8e-31 106.4 8.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Nop25 PF09805.4 EIW67112.1 - 0.12 12.4 6.9 0.15 12.1 4.8 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) ATP-synt_B PF00430.13 EIW67112.1 - 0.26 11.0 13.7 0.042 13.6 6.2 1.8 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF3552 PF12072.3 EIW67112.1 - 0.87 8.7 13.9 1.9 7.6 9.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Seryl_tRNA_N PF02403.17 EIW67112.1 - 1.1 9.2 8.4 3 7.8 5.5 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain eIF3g PF12353.3 EIW67112.1 - 1.3 8.9 5.3 1.9 8.4 3.7 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Symplekin_C PF12295.3 EIW67114.1 - 1.5e-48 165.0 0.1 4e-48 163.7 0.0 1.8 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 EIW67114.1 - 1.7e-37 129.1 0.0 3.3e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) CstA PF02554.9 EIW67115.1 - 3.6 6.1 5.7 4.9 5.7 3.9 1.1 1 0 0 1 1 1 0 Carbon starvation protein CstA zf-C2H2 PF00096.21 EIW67117.1 - 9.2e-14 50.8 9.7 6.8e-07 29.2 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW67117.1 - 2.3e-08 33.8 8.1 8.6e-05 22.6 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW67117.1 - 1.2e-07 31.6 19.5 1.7e-05 24.9 0.1 4.0 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIW67117.1 - 6.1e-07 29.4 0.8 6.7e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW67117.1 - 6.2e-05 23.0 1.3 0.00014 21.9 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EIW67117.1 - 0.0011 18.8 2.8 0.02 14.7 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIW67117.1 - 0.14 12.3 1.2 0.19 11.8 0.4 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 EIW67117.1 - 0.23 11.7 3.7 1 9.6 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.1 EIW67117.1 - 0.4 10.4 3.8 3.9 7.2 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Smr PF01713.16 EIW67118.1 - 1.8e-15 56.8 0.4 4e-15 55.7 0.1 1.7 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 EIW67118.1 - 6.3e-09 35.7 3.4 1.8e-08 34.2 1.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) RabGAP-TBC PF00566.13 EIW67119.1 - 3.6e-20 72.3 0.1 3.1e-19 69.3 0.1 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Phosphorylase PF00343.15 EIW67120.1 - 6.3e-299 992.9 0.0 7.4e-299 992.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Nefa_Nip30_N PF10187.4 EIW67121.1 - 3.1e-19 69.0 14.4 3.1e-19 69.0 10.0 2.1 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Lyase_1 PF00206.15 EIW67121.1 - 0.15 11.1 0.6 0.25 10.5 0.4 1.2 1 0 0 1 1 1 0 Lyase RRM_1 PF00076.17 EIW67122.1 - 2e-11 43.3 0.0 2.3e-10 39.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW67122.1 - 1.3e-07 31.5 0.0 3.7e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW67122.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 EIW67122.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Surp module MtrB PF05440.7 EIW67122.1 - 0.059 13.4 0.0 14 5.8 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B CTK3 PF12243.3 EIW67122.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Glyco_hydro_20 PF00728.17 EIW67123.1 - 3.4e-68 230.3 0.0 4.1e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EIW67123.1 - 2.7e-10 41.0 0.0 4.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EIW67123.1 - 5.3e-06 26.9 0.0 1.6e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 WSC PF01822.14 EIW67124.1 - 4.6e-33 112.9 49.3 4.2e-15 55.4 3.2 5.3 5 1 0 5 5 5 4 WSC domain DUF605 PF04652.11 EIW67124.1 - 1.1 8.5 19.5 1.5 8.1 13.5 1.1 1 0 0 1 1 1 0 Vta1 like UQ_con PF00179.21 EIW67125.1 - 3.4e-52 175.5 0.0 3.9e-52 175.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW67125.1 - 2e-05 24.3 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIW67125.1 - 0.0062 16.4 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EIW67125.1 - 0.024 14.2 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain Peptidase_C13 PF01650.13 EIW67126.1 - 4.1e-46 157.3 0.1 4.8e-46 157.1 0.1 1.0 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C14 PF00656.17 EIW67126.1 - 0.0003 20.5 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain MIT PF04212.13 EIW67127.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain p450 PF00067.17 EIW67128.1 - 2.1e-48 165.0 0.0 2.5e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 K_trans PF02705.11 EIW67129.1 - 9e-152 506.1 11.9 1.2e-151 505.7 8.2 1.2 1 0 0 1 1 1 1 K+ potassium transporter PAP2 PF01569.16 EIW67130.1 - 1.4e-15 57.1 6.4 1.4e-15 57.1 4.4 2.3 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EIW67130.1 - 8.6 6.7 13.2 0.57 10.4 2.6 3.2 3 1 0 3 3 3 0 PAP2 superfamily C-terminal Plus-3 PF03126.13 EIW67131.1 - 1.5e-18 66.8 0.0 3.1e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain MARVEL PF01284.18 EIW67136.1 - 4.2e-08 33.1 3.3 6.1e-08 32.5 2.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain Frag1 PF10277.4 EIW67136.1 - 0.0045 16.4 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Adeno_E3_14_5 PF04834.7 EIW67138.1 - 0.43 11.0 3.4 4.3 7.8 0.1 2.9 2 1 0 2 2 2 0 Early E3 14.5 kDa protein THF_DHG_CYH PF00763.18 EIW67140.1 - 1.4e-14 54.1 0.0 2.8e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EIW67140.1 - 2e-13 49.7 0.7 6.3e-08 31.8 0.0 3.1 2 2 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pex14_N PF04695.8 EIW67140.1 - 0.12 12.4 3.4 0.21 11.6 2.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TB2_DP1_HVA22 PF03134.14 EIW67141.1 - 2.8e-32 110.3 3.0 5.1e-32 109.4 2.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family HPP PF04982.8 EIW67141.1 - 0.069 12.9 0.6 0.13 12.1 0.3 1.5 1 1 0 1 1 1 0 HPP family Metallophos PF00149.23 EIW67142.1 - 2.1e-08 33.7 0.0 4.9e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW67142.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PHF5 PF03660.9 EIW67143.1 - 9.8e-52 173.5 9.8 1.1e-51 173.3 6.8 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EIW67143.1 - 0.053 13.3 14.5 0.77 9.6 9.3 2.7 1 1 0 1 1 1 0 Double zinc ribbon DNA_ligase_ZBD PF03119.11 EIW67143.1 - 0.29 10.8 3.7 2.5 7.8 0.1 2.9 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Prok-RING_1 PF14446.1 EIW67143.1 - 0.42 10.3 14.9 0.68 9.7 0.8 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 TF_Zn_Ribbon PF08271.7 EIW67143.1 - 3.3 7.0 18.2 1.8 7.9 2.5 2.9 2 2 0 2 2 2 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 EIW67143.1 - 6.3 6.5 10.6 1.6 8.4 1.5 2.4 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.7 EIW67143.1 - 9.1 6.1 12.7 4.5 7.1 4.7 2.6 1 1 0 1 1 1 0 zinc-ribbons DUF2781 PF10914.3 EIW67144.1 - 5.6e-30 104.0 6.1 6.9e-30 103.8 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Pkinase PF00069.20 EIW67145.1 - 3e-64 216.6 0.0 3.5e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67145.1 - 5.4e-28 97.7 0.0 6.8e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW67145.1 - 9.5e-06 24.7 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW67145.1 - 0.014 15.1 0.1 0.57 9.8 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EIW67145.1 - 0.026 13.5 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pirin PF02678.11 EIW67146.1 - 1.1e-28 99.2 0.6 1.7e-28 98.6 0.4 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EIW67146.1 - 3.6e-10 39.1 3.2 1.6e-07 30.7 0.3 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EIW67146.1 - 0.084 12.2 0.4 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF1996 PF09362.5 EIW67147.1 - 1e-60 205.3 0.6 1.5e-60 204.7 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Transp_cyt_pur PF02133.10 EIW67149.1 - 9.5e-93 311.1 41.8 1.2e-92 310.8 29.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Membr_traf_MHD PF10540.4 EIW67151.1 - 6e-11 42.2 0.0 1.6e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EIW67151.1 - 2.5e-07 30.4 0.0 6.4e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 C2 domain DUF1996 PF09362.5 EIW67152.1 - 1.6e-57 194.8 0.1 2.2e-57 194.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TauD PF02668.11 EIW67155.1 - 3.3e-49 167.8 0.2 4.1e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EIW67156.1 - 7.5e-14 51.1 18.7 2.1e-11 43.1 15.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF788 PF05620.6 EIW67156.1 - 0.012 15.4 1.8 0.018 14.8 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Abhydrolase_6 PF12697.2 EIW67157.1 - 8.4e-30 104.3 0.0 9.7e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW67157.1 - 2.6e-22 79.5 0.0 3.4e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW67157.1 - 9.4e-17 61.1 0.0 1.5e-15 57.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW67157.1 - 2.4e-06 26.9 0.2 0.013 14.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 EIW67157.1 - 4.3e-05 22.1 0.1 0.083 11.3 0.0 2.7 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 EIW67157.1 - 0.00019 21.2 0.0 0.00038 20.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 EIW67157.1 - 0.0062 16.1 0.0 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF1749 PF08538.5 EIW67157.1 - 0.021 13.7 0.3 1 8.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1749) Thioesterase PF00975.15 EIW67157.1 - 0.085 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Fungal_trans PF04082.13 EIW67158.1 - 4.1e-13 48.7 0.1 5.8e-13 48.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW67158.1 - 1.7e-05 24.6 10.1 1.7e-05 24.6 7.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Antiterm PF03589.8 EIW67158.1 - 0.34 11.0 1.3 29 4.8 0.2 2.8 2 1 1 3 3 3 0 Antitermination protein DIOX_N PF14226.1 EIW67159.1 - 1.2e-10 41.9 0.0 2.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW67159.1 - 2.2e-10 40.7 0.0 4.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EIW67160.1 - 5.4e-32 110.8 20.4 5.4e-32 110.8 14.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.9 EIW67161.1 - 1.5e-25 90.2 0.0 2.6e-25 89.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW67161.1 - 7.7e-10 39.0 0.0 1.9e-07 31.3 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW67161.1 - 0.0032 16.3 0.0 1.3 7.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIW67161.1 - 0.04 13.9 0.0 18 5.4 0.0 2.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HpcH_HpaI PF03328.9 EIW67162.1 - 6.4e-33 113.4 0.0 7.4e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Response_reg PF00072.19 EIW67162.1 - 0.012 15.5 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Response regulator receiver domain Transp_cyt_pur PF02133.10 EIW67163.1 - 5.1e-78 262.5 35.9 2.7e-52 177.8 7.9 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4580 PF15162.1 EIW67164.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) 2OG-FeII_Oxy PF03171.15 EIW67165.1 - 2.8e-25 88.4 0.1 4.8e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIW67165.1 - 1.7e-16 60.7 0.0 3.1e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Zn_clus PF00172.13 EIW67166.1 - 0.00069 19.4 10.6 0.0013 18.5 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp_Glu_race PF01177.17 EIW67167.1 - 1.5e-28 100.1 0.0 1.8e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.6 EIW67167.1 - 0.0044 16.3 0.0 0.012 14.9 0.0 1.6 2 0 0 2 2 2 1 AroM protein Collagen PF01391.13 EIW67168.1 - 0.00069 19.1 6.5 0.0018 17.7 4.5 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) NIR_SIR PF01077.17 EIW67169.1 - 2e-51 173.4 0.0 1.6e-45 154.3 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EIW67169.1 - 3.7e-34 116.1 0.0 4.5e-16 58.2 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EIW67169.1 - 1.4e-20 73.7 0.0 2.8e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin PspA_IM30 PF04012.7 EIW67170.1 - 0.0094 15.3 2.4 0.013 14.8 1.6 1.1 1 0 0 1 1 1 1 PspA/IM30 family CENP-Q PF13094.1 EIW67170.1 - 0.055 13.4 0.3 0.094 12.7 0.2 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4140 PF13600.1 EIW67170.1 - 0.065 13.6 1.5 0.15 12.5 1.0 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.7 EIW67170.1 - 0.12 12.1 0.6 0.21 11.3 0.2 1.5 2 0 0 2 2 2 0 Laminin Domain II SP_C-Propep PF08999.5 EIW67171.1 - 2.9 7.4 4.8 2.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Glyco_trans_2_3 PF13632.1 EIW67171.1 - 6.6 6.3 13.2 49 3.5 9.2 2.2 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Pkinase PF00069.20 EIW67172.1 - 6.3e-40 136.9 0.0 4.1e-21 75.2 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67172.1 - 2.9e-22 78.9 0.0 1.1e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Propep_M14 PF02244.11 EIW67172.1 - 0.021 14.4 0.1 6.5 6.5 0.0 3.2 3 0 0 3 3 3 0 Carboxypeptidase activation peptide CD4-extracel PF09191.5 EIW67173.1 - 0.01 15.8 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 0 CD4, extracellular DUF3899 PF13038.1 EIW67173.1 - 0.023 14.8 3.2 1.6 8.9 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) Cellulase PF00150.13 EIW67174.1 - 6.7e-12 45.1 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SNF2_N PF00176.18 EIW67175.1 - 7.2e-67 225.2 0.2 1.2e-66 224.5 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EIW67175.1 - 2.7e-25 88.4 2.5 3.4e-25 88.1 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EIW67175.1 - 1.3e-17 63.2 3.4 8.2e-13 47.8 0.6 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EIW67175.1 - 1.7e-14 53.4 0.0 3.7e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW67175.1 - 5.7e-06 26.2 0.1 0.00042 20.1 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.26 EIW67175.1 - 0.017 15.1 1.9 0.046 13.7 0.3 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain DDE_5 PF13546.1 EIW67175.1 - 0.021 13.6 0.0 0.041 12.7 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease DGF-1_4 PF11024.3 EIW67176.1 - 4.4 7.7 13.3 0.9 9.9 1.3 2.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 COG2 PF06148.6 EIW67178.1 - 5.2e-30 104.0 0.1 1.6e-29 102.4 0.0 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 EIW67178.1 - 2.4e-19 69.6 0.0 5.2e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) IncA PF04156.9 EIW67178.1 - 0.052 13.1 1.4 0.17 11.4 1.0 1.8 1 0 0 1 1 1 0 IncA protein Zw10 PF06248.8 EIW67178.1 - 0.094 10.8 0.0 1.4 6.9 0.0 2.4 3 0 0 3 3 3 0 Centromere/kinetochore Zw10 UPF0029 PF01205.14 EIW67179.1 - 0.081 12.6 0.0 6 6.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 His_Phos_1 PF00300.17 EIW67181.1 - 1.3e-30 106.5 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.11 EIW67182.1 - 9.6e-05 21.2 7.7 9.6e-05 21.2 5.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M20 PF01546.23 EIW67186.1 - 5.2e-21 75.0 0.0 6.7e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIW67186.1 - 9.8e-11 41.3 0.0 1.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Ras PF00071.17 EIW67187.1 - 3e-65 218.5 0.8 3.5e-65 218.3 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW67187.1 - 8.6e-21 74.6 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW67187.1 - 4.7e-18 65.0 0.2 6.2e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW67187.1 - 9.7e-07 28.1 0.1 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW67187.1 - 2.1e-06 27.3 0.2 4.5e-06 26.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EIW67187.1 - 4.3e-06 26.0 0.1 5.3e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EIW67187.1 - 4.4e-05 23.4 0.1 0.0001 22.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIW67187.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EIW67187.1 - 0.0014 17.9 0.1 0.011 14.9 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EIW67187.1 - 0.0025 17.0 0.5 0.014 14.5 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EIW67187.1 - 0.0033 17.6 0.0 0.41 10.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW67187.1 - 0.019 14.9 0.1 0.036 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EIW67187.1 - 0.02 14.4 1.3 0.11 12.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EIW67187.1 - 0.031 13.9 0.0 0.069 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.13 EIW67187.1 - 0.087 11.8 0.0 0.21 10.5 0.0 1.6 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 EIW67187.1 - 0.095 12.9 0.4 0.25 11.6 0.3 1.9 1 1 0 1 1 1 0 ABC transporter NEMO PF11577.3 EIW67188.1 - 0.002 17.8 3.7 0.79 9.5 0.1 3.1 2 0 0 2 2 2 2 NF-kappa-B essential modulator NEMO Mpv17_PMP22 PF04117.7 EIW67191.1 - 2.5e-23 81.4 0.9 5.6e-23 80.3 0.7 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribonuclease_3 PF00636.21 EIW67194.1 - 0.0057 17.0 3.8 0.0069 16.8 0.0 3.0 3 0 0 3 3 3 1 Ribonuclease III domain DUF3573 PF12097.3 EIW67194.1 - 0.64 8.5 4.4 2.2 6.8 3.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Aminotran_3 PF00202.16 EIW67195.1 - 1.9e-75 253.8 0.0 2.3e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF1510 PF07423.6 EIW67201.1 - 8.4e-06 25.3 13.0 8.6e-06 25.2 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) CDC45 PF02724.9 EIW67201.1 - 0.00035 18.7 15.6 0.00039 18.5 10.8 1.0 1 0 0 1 1 1 1 CDC45-like protein Zip PF02535.17 EIW67201.1 - 0.00047 19.2 0.6 0.0005 19.1 0.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Tim54 PF11711.3 EIW67201.1 - 0.00085 18.0 8.2 0.001 17.7 5.7 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.7 EIW67201.1 - 0.0012 16.9 28.0 0.0013 16.7 19.4 1.0 1 0 0 1 1 1 1 Nop14-like family Spore_coat_CotO PF14153.1 EIW67201.1 - 0.009 15.4 21.9 0.012 15.0 15.2 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Vfa1 PF08432.5 EIW67201.1 - 0.0095 15.9 14.7 0.011 15.7 10.2 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SAPS PF04499.10 EIW67201.1 - 0.011 14.4 10.5 0.013 14.1 7.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.12 EIW67201.1 - 0.014 15.1 12.2 0.017 14.9 8.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.7 EIW67201.1 - 0.028 13.1 3.0 0.035 12.8 2.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NAM-associated PF14303.1 EIW67201.1 - 0.036 14.3 18.2 0.041 14.2 12.6 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain BUD22 PF09073.5 EIW67201.1 - 0.044 12.8 23.5 0.052 12.6 16.3 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.8 EIW67201.1 - 0.053 13.4 19.9 0.062 13.1 13.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gag_spuma PF03276.9 EIW67201.1 - 0.063 11.5 1.3 0.072 11.4 0.9 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF3464 PF11947.3 EIW67201.1 - 0.072 12.5 0.6 0.11 11.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) YqfQ PF14181.1 EIW67201.1 - 0.087 12.8 19.9 0.11 12.4 13.8 1.1 1 0 0 1 1 1 0 YqfQ-like protein Mem_trans PF03547.13 EIW67201.1 - 0.089 11.0 1.7 0.091 11.0 1.2 1.2 1 0 0 1 1 1 0 Membrane transport protein Drc1-Sld2 PF11719.3 EIW67201.1 - 0.1 11.6 13.5 0.11 11.5 9.4 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein SDA1 PF05285.7 EIW67201.1 - 0.12 11.5 27.6 0.14 11.3 19.2 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 EIW67201.1 - 0.13 11.8 24.4 0.17 11.4 16.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Pilt PF15453.1 EIW67201.1 - 0.17 11.5 11.9 0.19 11.3 8.2 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF2457 PF10446.4 EIW67201.1 - 0.2 10.3 28.8 0.23 10.1 20.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ycf1 PF05758.7 EIW67201.1 - 0.22 9.1 14.8 0.23 9.1 10.2 1.1 1 0 0 1 1 1 0 Ycf1 Raftlin PF15250.1 EIW67201.1 - 0.23 9.9 8.0 0.25 9.8 5.5 1.1 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.8 EIW67201.1 - 0.25 9.8 7.7 0.31 9.5 5.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4011 PF13195.1 EIW67201.1 - 0.33 10.9 6.0 0.43 10.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Astro_capsid PF03115.9 EIW67201.1 - 0.33 9.1 5.2 0.38 8.9 3.6 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Hus1 PF04005.7 EIW67201.1 - 0.36 9.7 1.9 0.5 9.2 1.3 1.3 1 0 0 1 1 1 0 Hus1-like protein VID27 PF08553.5 EIW67201.1 - 0.39 8.9 24.2 0.47 8.5 16.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Mpp10 PF04006.7 EIW67201.1 - 0.44 8.8 32.8 0.51 8.6 22.7 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF4045 PF13254.1 EIW67201.1 - 0.47 9.6 7.7 0.52 9.5 5.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF4246 PF14033.1 EIW67201.1 - 0.56 8.7 9.0 0.62 8.6 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Pox_Ag35 PF03286.9 EIW67201.1 - 0.59 9.6 19.3 0.94 8.9 13.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.7 EIW67201.1 - 0.66 9.8 20.6 0.81 9.5 14.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.3 EIW67201.1 - 0.66 9.2 16.7 0.81 8.9 11.6 1.0 1 0 0 1 1 1 0 SprA-related family CENP-T PF15511.1 EIW67201.1 - 0.91 8.6 18.3 1.1 8.4 12.7 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Dynamin_N PF00350.18 EIW67201.1 - 0.92 9.3 3.9 1.1 9.0 2.7 1.3 1 0 0 1 1 1 0 Dynamin family PPP4R2 PF09184.6 EIW67201.1 - 0.97 8.9 28.4 1.6 8.2 19.7 1.3 1 0 0 1 1 1 0 PPP4R2 DHHW PF14286.1 EIW67201.1 - 1.1 8.4 8.6 1.4 8.1 6.0 1.1 1 0 0 1 1 1 0 DHHW protein DUF4613 PF15390.1 EIW67201.1 - 1.4 6.9 4.4 1.7 6.7 3.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) SID-1_RNA_chan PF13965.1 EIW67201.1 - 1.6 6.8 4.3 1.8 6.6 3.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 tRNA-synt_1c PF00749.16 EIW67201.1 - 1.7 7.1 9.4 2 6.9 6.5 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain SpoIIP PF07454.6 EIW67201.1 - 1.7 7.7 11.8 2.1 7.4 8.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2722 PF10846.3 EIW67201.1 - 1.8 7.5 8.1 2 7.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Daxx PF03344.10 EIW67201.1 - 2.2 6.6 37.7 2.7 6.3 26.2 1.0 1 0 0 1 1 1 0 Daxx Family DUF3381 PF11861.3 EIW67201.1 - 2.3 7.6 34.9 3.3 7.2 24.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CPSF100_C PF13299.1 EIW67201.1 - 2.4 8.3 8.8 3.3 7.8 6.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Cellulose_synt PF03552.9 EIW67201.1 - 2.5 6.3 6.7 2.9 6.0 4.7 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF3306 PF11748.3 EIW67201.1 - 2.8 8.6 16.7 3.8 8.1 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Rtf2 PF04641.7 EIW67201.1 - 3.5 6.7 15.1 4.5 6.3 10.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Paf1 PF03985.8 EIW67201.1 - 4.3 5.9 33.5 5.2 5.7 23.2 1.1 1 0 0 1 1 1 0 Paf1 Hid1 PF12722.2 EIW67201.1 - 4.3 4.9 7.2 4.6 4.7 5.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CobT PF06213.7 EIW67201.1 - 4.8 6.2 33.1 5.7 5.9 23.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tom37_C PF11801.3 EIW67201.1 - 6.9 6.5 10.6 9.5 6.0 7.4 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Afi1 PF07792.7 EIW67201.1 - 6.9 6.6 10.4 9.7 6.1 7.2 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF740 PF05340.7 EIW67201.1 - 9.7 4.4 25.4 12 4.1 17.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) UBN2_2 PF14227.1 EIW67204.1 - 4.2e-08 32.7 0.0 1.3e-07 31.1 0.0 1.8 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW67204.1 - 5.5e-07 29.3 0.0 1.3e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW67204.1 - 0.00029 20.4 6.6 0.1 12.1 0.5 3.4 4 0 0 4 4 4 3 gag-polypeptide of LTR copia-type Trypan_PARP PF05887.6 EIW67204.1 - 0.97 9.2 3.6 1.9 8.3 2.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDE_1 PF03184.14 EIW67205.1 - 1.8e-31 108.9 0.0 2.7e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EIW67205.1 - 0.057 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF2076 PF09849.4 EIW67205.1 - 0.079 13.0 1.0 0.14 12.1 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4613 PF15390.1 EIW67205.1 - 0.12 10.5 0.5 0.2 9.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) AATF-Che1 PF13339.1 EIW67205.1 - 0.37 10.9 4.1 0.97 9.5 2.8 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor GETHR PF05671.6 EIW67206.1 - 9.9 5.4 46.8 1.5e+04 -24.5 32.5 4.3 1 1 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) DDE_1 PF03184.14 EIW67208.1 - 1e-25 90.1 0.0 1.8e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW67208.1 - 0.00024 20.8 0.0 0.00082 19.1 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EIW67208.1 - 0.0033 16.9 0.0 0.022 14.3 0.0 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_7 PF02796.10 EIW67208.1 - 0.009 15.8 0.0 0.066 13.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DUF1777 PF08648.7 EIW67210.1 - 8.1 6.1 18.9 17 5.1 13.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RRM_1 PF00076.17 EIW67212.1 - 3.5e-79 260.4 1.5 2.4e-19 68.7 0.2 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW67212.1 - 1e-50 169.5 0.4 5e-13 48.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW67212.1 - 5e-37 125.5 0.1 1.1e-10 41.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIW67212.1 - 2.3e-29 100.8 1.3 6e-29 99.5 0.9 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EIW67212.1 - 2.1e-07 30.6 0.1 0.0092 15.7 0.0 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EIW67212.1 - 0.0002 21.0 0.0 0.15 11.8 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EIW67212.1 - 0.0012 18.5 2.9 2.8 7.7 0.1 3.8 4 0 0 4 4 4 2 Limkain b1 PAT1 PF09770.4 EIW67212.1 - 2.6 6.1 19.6 4.6 5.3 13.6 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Epimerase PF01370.16 EIW67213.1 - 1.2e-09 37.9 0.0 2.2e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW67213.1 - 3.1e-07 30.5 0.0 4.6e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIW67213.1 - 5.3e-07 28.8 0.0 0.001 18.0 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.8 EIW67213.1 - 5.5e-06 25.8 0.0 9.8e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EIW67213.1 - 0.0082 15.0 0.0 0.052 12.4 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein Flavodoxin_5 PF12724.2 EIW67213.1 - 0.019 14.9 0.3 18 5.3 0.0 3.1 2 1 1 3 3 3 0 Flavodoxin domain 3Beta_HSD PF01073.14 EIW67213.1 - 0.028 13.1 0.0 0.069 11.8 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EIW67213.1 - 0.1 12.9 0.0 1.2 9.4 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain A_deaminase PF00962.17 EIW67214.1 - 1.4e-16 60.3 0.0 2.4e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase HTH_Tnp_Tc3_2 PF01498.13 EIW67218.1 - 1.2e-11 44.5 10.2 3.1e-11 43.1 4.1 2.1 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 EIW67218.1 - 1.5e-07 30.8 2.0 1.2e-06 27.9 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.1 EIW67218.1 - 3.7e-07 30.2 2.7 5.8e-07 29.6 0.3 1.9 1 1 1 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 EIW67218.1 - 8.3e-06 25.7 0.6 7.2e-05 22.6 0.0 2.7 3 1 1 4 4 4 1 Helix-turn-helix domain HTH_32 PF13565.1 EIW67218.1 - 1.7e-05 25.5 1.2 1.7e-05 25.5 0.8 2.4 1 1 2 3 3 3 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIW67218.1 - 7.7e-05 21.7 0.0 0.00016 20.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_21 PF13276.1 EIW67218.1 - 0.00021 21.2 2.6 1.3 9.0 2.1 2.7 2 1 0 2 2 2 2 HTH-like domain MarR_2 PF12802.2 EIW67218.1 - 0.00093 18.8 0.1 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_Tnp_4 PF13613.1 EIW67218.1 - 0.0019 17.6 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_Crp_2 PF13545.1 EIW67218.1 - 0.0039 16.9 0.5 2.5 7.9 0.0 2.5 2 1 0 2 2 2 2 Crp-like helix-turn-helix domain Integrase_1 PF12835.2 EIW67218.1 - 0.0056 16.4 0.2 0.007 16.1 0.2 1.1 1 0 0 1 1 1 1 Integrase HTH_6 PF01418.12 EIW67218.1 - 0.0074 15.9 0.1 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_IclR PF09339.5 EIW67218.1 - 0.055 13.0 0.2 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_38 PF13936.1 EIW67218.1 - 0.094 12.2 1.5 0.33 10.5 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.1 EIW67218.1 - 0.11 11.8 0.1 0.84 9.0 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_7 PF02796.10 EIW67218.1 - 0.14 12.0 1.0 6.4 6.7 0.0 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_31 PF13560.1 EIW67218.1 - 0.47 10.6 0.0 0.47 10.6 0.0 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain Med25_SD1 PF11235.3 EIW67220.1 - 2.6 8.3 10.0 0.12 12.7 1.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 Arrestin_N PF00339.24 EIW67223.1 - 0.091 12.5 0.0 0.24 11.1 0.0 1.8 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain CMAS PF02353.15 EIW67226.1 - 9.1e-66 221.7 0.2 1.2e-65 221.3 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EIW67226.1 - 1.3e-12 47.6 0.0 2.4e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW67226.1 - 4e-11 43.2 0.0 1.5e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW67226.1 - 3.9e-07 30.4 0.0 6.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW67226.1 - 5.6e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW67226.1 - 2.9e-05 23.7 0.0 7.4e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 EIW67226.1 - 8.4e-05 21.9 0.0 0.00018 20.8 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EIW67226.1 - 0.0001 22.8 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW67226.1 - 0.00029 20.8 0.0 0.0021 18.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW67226.1 - 0.00029 20.2 0.0 0.00046 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EIW67226.1 - 0.0022 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EIW67226.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 EIW67226.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF2884 PF11101.3 EIW67228.1 - 0.0033 16.8 0.4 0.0054 16.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2884) NTR PF01759.16 EIW67229.1 - 0.049 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 UNC-6/NTR/C345C module Sulfate_transp PF00916.15 EIW67232.1 - 4.9e-52 176.6 7.0 4.9e-52 176.6 4.8 2.0 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EIW67232.1 - 3.1e-27 94.0 4.0 3.1e-27 94.0 2.8 3.6 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EIW67232.1 - 9.1e-16 57.3 0.0 1.5e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EIW67232.1 - 0.015 15.3 0.1 0.048 13.6 0.0 2.0 1 0 0 1 1 1 0 STAS domain PGG PF13962.1 EIW67232.1 - 0.14 11.7 6.5 1.9 8.1 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function DUF1691 PF07950.6 EIW67234.1 - 0.082 12.8 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Latarcin PF10279.4 EIW67235.1 - 0.065 13.4 4.2 0.99 9.6 0.8 2.6 2 1 0 2 2 2 0 Latarcin precursor SR-25 PF10500.4 EIW67235.1 - 9.2 5.6 28.2 0.052 13.0 11.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein G-gamma PF00631.17 EIW67236.1 - 1.7e-23 82.1 0.0 1.9e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain Elongin_A PF06881.6 EIW67237.1 - 1.9e-16 60.3 2.6 3.5e-16 59.5 1.8 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SUR7 PF06687.7 EIW67237.1 - 3.2e-14 52.9 9.6 5e-14 52.3 6.7 1.2 1 0 0 1 1 1 1 SUR7/PalI family Ribosomal_S17 PF00366.15 EIW67237.1 - 0.035 14.1 0.6 0.09 12.8 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S17 Clc-like PF07062.7 EIW67237.1 - 0.74 9.0 4.8 1.2 8.3 3.3 1.2 1 0 0 1 1 1 0 Clc-like F-box-like PF12937.2 EIW67238.1 - 7.2e-05 22.4 0.0 0.00027 20.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like Tir_receptor_C PF07489.6 EIW67238.1 - 0.0022 17.7 1.1 0.0022 17.7 0.8 1.7 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus F-box PF00646.28 EIW67238.1 - 0.014 15.0 0.0 0.044 13.4 0.0 1.9 1 0 0 1 1 1 0 F-box domain Aminotran_5 PF00266.14 EIW67239.1 - 4.1e-34 117.9 0.0 1.4e-24 86.5 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V SpoIIID PF12116.3 EIW67239.1 - 0.12 12.3 0.6 0.27 11.2 0.4 1.5 1 0 0 1 1 1 0 Stage III sporulation protein D Osteopontin PF00865.13 EIW67240.1 - 0.18 10.9 0.1 0.26 10.4 0.1 1.1 1 0 0 1 1 1 0 Osteopontin Macro PF01661.16 EIW67241.1 - 3.1e-36 123.8 0.1 4.1e-36 123.4 0.1 1.1 1 0 0 1 1 1 1 Macro domain Daxx PF03344.10 EIW67244.1 - 0.00011 20.9 8.1 0.00014 20.4 5.6 1.3 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 EIW67244.1 - 0.00029 18.9 18.5 0.00041 18.4 12.8 1.2 1 0 0 1 1 1 1 Nop14-like family DUF1510 PF07423.6 EIW67244.1 - 0.058 12.7 7.6 0.093 12.0 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EIW67244.1 - 0.066 11.2 19.1 0.1 10.5 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein CBP4 PF07960.6 EIW67244.1 - 0.13 11.8 1.8 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 CBP4 RRN3 PF05327.6 EIW67244.1 - 1.5 6.8 14.4 2.4 6.1 10.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.7 EIW67244.1 - 1.9 7.5 21.2 3.4 6.7 14.7 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 EIW67244.1 - 5.9 5.8 17.2 9.1 5.2 11.9 1.3 1 0 0 1 1 1 0 BUD22 zf-H2C2 PF09337.5 EIW67245.1 - 0.0083 15.5 3.0 0.017 14.5 2.1 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Mucin PF01456.12 EIW67245.1 - 5 6.9 8.5 9.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Myb_DNA-bind_4 PF13837.1 EIW67246.1 - 0.0014 18.6 0.2 0.0042 17.1 0.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Methyltransf_31 PF13847.1 EIW67247.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lactamase_B_2 PF12706.2 EIW67248.1 - 1.3e-12 47.6 0.0 2.7e-08 33.5 0.0 2.9 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIW67248.1 - 9.8e-08 31.8 0.1 2.3e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EIW67248.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 1 0 0 1 1 1 0 tRNase Z endonuclease PDEase_II PF02112.10 EIW67248.1 - 0.036 12.9 0.2 0.058 12.3 0.2 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Aldo_ket_red PF00248.16 EIW67249.1 - 2.5e-64 216.8 0.0 2.9e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HA PF03457.9 EIW67249.1 - 0.086 12.9 0.1 14 5.8 0.0 2.8 3 0 0 3 3 3 0 Helicase associated domain BRO1 PF03097.13 EIW67251.1 - 3.2e-05 22.8 0.0 6.8e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 BRO1-like domain Endonuclease_NS PF01223.18 EIW67252.1 - 2e-49 168.0 0.0 2.6e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease MHYT PF03707.11 EIW67253.1 - 0.00018 21.5 30.3 0.002 18.1 4.1 4.4 5 0 0 5 5 5 3 Bacterial signalling protein N terminal repeat Chitin_synth_1 PF01644.12 EIW67254.1 - 1.2e-63 213.7 0.0 2e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIW67254.1 - 5.6e-27 93.2 0.0 1.1e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIW67254.1 - 1.9e-24 85.9 0.0 1.8e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EIW67254.1 - 4e-10 39.7 4.2 1.9e-09 37.5 2.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW67254.1 - 1.6e-07 31.3 0.0 6e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cmc1 PF08583.5 EIW67255.1 - 2.3e-15 56.1 1.9 2.6e-15 55.9 1.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Aldo_ket_red PF00248.16 EIW67255.1 - 0.0016 17.3 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family GIIM PF08388.6 EIW67255.1 - 0.047 13.4 0.4 0.057 13.2 0.3 1.2 1 0 0 1 1 1 0 Group II intron, maturase-specific domain NDUF_B7 PF05676.8 EIW67255.1 - 0.056 12.8 0.7 0.082 12.3 0.5 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 EIW67255.1 - 0.22 11.5 1.0 0.45 10.5 0.1 1.9 2 0 0 2 2 2 0 CHCH domain zf-DNL PF05180.7 EIW67256.1 - 8.6e-30 102.2 0.5 1e-29 102.0 0.4 1.1 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.13 EIW67256.1 - 0.062 12.9 1.3 2.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-CSL PF05207.8 EIW67256.1 - 0.1 12.0 0.9 0.18 11.3 0.6 1.4 1 0 0 1 1 1 0 CSL zinc finger Zn-ribbon_8 PF09723.5 EIW67256.1 - 0.26 11.2 2.4 0.71 9.8 1.6 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 EIW67256.1 - 0.41 10.3 0.0 0.41 10.3 0.0 2.0 4 0 0 4 4 4 0 zinc-ribbon domain Spindle_Spc25 PF08234.7 EIW67257.1 - 3.4e-23 81.4 0.6 1.2e-22 79.6 0.1 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 EIW67257.1 - 0.00084 18.0 3.0 0.0011 17.6 2.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein MT PF12777.2 EIW67257.1 - 0.013 14.2 0.9 0.018 13.8 0.6 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor AAA_13 PF13166.1 EIW67257.1 - 0.027 12.9 2.5 0.032 12.7 1.7 1.0 1 0 0 1 1 1 0 AAA domain MAT1 PF06391.8 EIW67257.1 - 0.15 11.6 5.0 0.21 11.1 3.5 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF4661 PF15576.1 EIW67257.1 - 0.17 11.5 2.0 0.23 11.0 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF2968 PF11180.3 EIW67257.1 - 0.19 11.1 7.3 0.26 10.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ADIP PF11559.3 EIW67257.1 - 0.19 11.6 8.7 0.33 10.8 5.8 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 EIW67257.1 - 0.24 11.2 1.9 0.66 9.8 1.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 EIW67257.1 - 0.28 10.6 5.3 0.25 10.8 1.3 2.2 1 1 1 2 2 2 0 Septum formation initiator Baculo_PEP_C PF04513.7 EIW67257.1 - 0.29 10.9 4.1 0.42 10.4 1.7 1.9 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.4 EIW67257.1 - 0.31 9.7 4.7 0.43 9.2 3.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF972 PF06156.8 EIW67257.1 - 0.32 11.3 4.2 0.47 10.8 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 EIW67257.1 - 0.38 9.8 3.7 0.68 9.0 2.5 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Med9 PF07544.8 EIW67257.1 - 0.38 10.5 3.9 0.42 10.3 1.6 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EIW67257.1 - 0.4 10.2 6.4 0.57 9.7 4.5 1.2 1 0 0 1 1 1 0 IncA protein DUF2951 PF11166.3 EIW67257.1 - 0.45 10.3 3.1 1.1 9.0 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) TMF_TATA_bd PF12325.3 EIW67257.1 - 0.65 9.7 10.8 0.98 9.1 6.5 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 EIW67257.1 - 0.7 7.6 3.0 0.86 7.3 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cortex-I_coil PF09304.5 EIW67257.1 - 1.9 8.5 12.6 6.6 6.8 1.8 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil Fez1 PF06818.10 EIW67257.1 - 4.1 7.3 11.5 1.6 8.7 1.3 2.1 1 1 1 2 2 2 0 Fez1 Spc24 PF08286.6 EIW67257.1 - 9.5 5.9 9.0 4.5 6.9 1.9 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Pkinase PF00069.20 EIW67258.1 - 3.9e-55 186.8 0.0 2e-54 184.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67258.1 - 1.4e-30 106.2 0.2 8.9e-22 77.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW67258.1 - 3.7e-06 26.1 0.1 0.0059 15.6 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EIW67258.1 - 0.0023 17.7 0.2 0.045 13.4 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family AAA PF00004.24 EIW67259.1 - 3.9e-11 43.2 0.0 9.2e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW67259.1 - 2.7e-10 40.5 0.0 4.1e-09 36.6 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW67259.1 - 9.4e-07 29.0 0.0 3.1e-06 27.3 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW67259.1 - 0.0011 18.7 0.3 0.0031 17.2 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EIW67259.1 - 0.012 14.6 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EIW67259.1 - 0.054 13.1 0.1 0.33 10.6 0.0 2.3 3 0 0 3 3 3 0 NTPase AAA_11 PF13086.1 EIW67259.1 - 0.069 12.7 0.0 0.069 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EIW67259.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 EIW67259.1 - 0.17 11.5 2.8 0.3 10.7 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase Alpha-amylase PF00128.19 EIW67260.1 - 2.5e-65 220.9 1.0 3.3e-65 220.5 0.7 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EIW67260.1 - 1.1e-15 57.4 0.3 2.4e-15 56.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.1 EIW67260.1 - 0.002 17.1 0.1 0.0032 16.4 0.1 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Septin PF00735.13 EIW67262.1 - 3.6e-105 351.0 0.2 7.2e-105 350.0 0.0 1.5 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.18 EIW67262.1 - 2e-05 24.5 1.5 0.084 12.6 0.0 2.8 3 0 0 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 EIW67262.1 - 0.00013 21.9 0.0 0.0003 20.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW67262.1 - 0.00044 19.4 0.0 0.00088 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIW67262.1 - 0.00046 19.6 0.0 0.0073 15.7 0.0 2.3 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain DUF87 PF01935.12 EIW67262.1 - 0.0018 18.1 1.3 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EIW67262.1 - 0.0032 16.9 0.0 0.0062 16.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family PduV-EutP PF10662.4 EIW67262.1 - 0.02 14.3 0.0 0.052 13.0 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.8 EIW67262.1 - 0.024 13.4 0.2 0.055 12.2 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 EIW67262.1 - 0.025 14.6 0.0 0.23 11.6 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 EIW67262.1 - 0.035 13.9 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.11 EIW67262.1 - 0.039 13.0 0.0 2.5 7.1 0.0 2.3 2 0 0 2 2 2 0 AIG1 family AAA_10 PF12846.2 EIW67262.1 - 0.049 13.0 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 EIW67262.1 - 0.05 12.4 0.0 0.091 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 EIW67262.1 - 0.062 14.1 1.6 0.33 11.7 0.2 2.7 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EIW67262.1 - 0.066 13.1 0.3 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EIW67262.1 - 0.11 12.2 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sec34 PF04136.10 EIW67263.1 - 5.1e-28 97.7 0.1 1.4e-27 96.3 0.1 1.7 1 0 0 1 1 1 1 Sec34-like family SRP54 PF00448.17 EIW67264.1 - 2e-74 249.3 0.3 3.5e-74 248.5 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EIW67264.1 - 1.2e-20 73.7 0.9 1.2e-20 73.7 0.6 4.3 4 0 0 4 4 4 2 Signal peptide binding domain SRP54_N PF02881.14 EIW67264.1 - 1.7e-14 53.6 2.0 1.7e-14 53.6 1.4 1.8 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EIW67264.1 - 7.5e-07 29.1 0.2 5.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EIW67264.1 - 2.5e-05 23.8 0.3 0.00011 21.7 0.2 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EIW67264.1 - 5.1e-05 22.7 1.0 0.00025 20.5 0.1 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EIW67264.1 - 0.00087 19.0 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EIW67264.1 - 0.0038 16.0 0.1 0.015 14.1 0.0 2.0 2 0 0 2 2 2 1 ArgK protein AAA_31 PF13614.1 EIW67264.1 - 0.0064 16.4 0.0 1.8 8.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EIW67264.1 - 0.01 16.6 0.0 0.029 15.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW67264.1 - 0.019 15.1 0.0 0.054 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EIW67264.1 - 0.032 13.6 0.1 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_19 PF13245.1 EIW67264.1 - 0.051 13.3 0.1 0.2 11.4 0.1 2.0 1 0 0 1 1 1 0 Part of AAA domain ATP_bind_1 PF03029.12 EIW67264.1 - 0.065 12.7 0.1 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 EIW67264.1 - 0.071 11.7 0.0 2.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain APS_kinase PF01583.15 EIW67264.1 - 0.093 12.3 0.1 0.35 10.5 0.0 1.9 1 1 1 2 2 2 0 Adenylylsulphate kinase Yip1 PF04893.12 EIW67265.1 - 1.2e-18 67.2 15.4 1.6e-18 66.8 10.7 1.1 1 0 0 1 1 1 1 Yip1 domain DUF4199 PF13858.1 EIW67265.1 - 0.0084 16.0 3.1 0.0084 16.0 2.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) DUF1282 PF06930.7 EIW67265.1 - 0.2 11.3 10.3 0.52 9.9 7.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) LIM PF00412.17 EIW67266.1 - 1.3 9.1 7.1 6.2 6.9 1.8 2.4 2 0 0 2 2 2 0 LIM domain Nol1_Nop2_Fmu PF01189.12 EIW67267.1 - 1.9e-23 83.2 0.0 2.9e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family EF-hand_6 PF13405.1 EIW67268.1 - 1.6e-12 46.1 3.2 4.7e-06 26.0 0.1 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EIW67268.1 - 6.2e-11 40.7 5.9 1.7e-06 26.9 0.1 3.9 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 EIW67268.1 - 9e-10 38.5 0.1 4.4e-05 23.5 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EIW67268.1 - 0.00026 20.1 1.6 0.0021 17.3 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EIW67268.1 - 0.0016 18.0 3.1 0.052 13.1 0.3 3.1 4 1 1 5 5 5 1 EF-hand domain pair EFhand_Ca_insen PF08726.5 EIW67268.1 - 0.037 13.9 0.1 13 5.8 0.1 3.0 2 1 0 2 2 2 0 Ca2+ insensitive EF hand Apc1 PF12859.2 EIW67269.1 - 2.4e-09 37.3 7.7 0.0004 20.5 0.4 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EIW67269.1 - 7e-05 22.8 12.4 0.24 11.7 0.0 5.5 5 0 0 5 5 5 4 Proteasome/cyclosome repeat ZZ PF00569.12 EIW67270.1 - 2.8e-24 84.3 27.9 9.8e-09 34.6 2.6 3.7 4 0 0 4 4 4 3 Zinc finger, ZZ type Neugrin PF06413.6 EIW67270.1 - 0.25 11.1 4.6 1.9 8.2 2.9 2.4 2 0 0 2 2 2 0 Neugrin Lzipper-MIP1 PF14389.1 EIW67270.1 - 0.6 10.2 4.9 26 4.9 0.0 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Atg14 PF10186.4 EIW67270.1 - 4.5 6.1 6.2 40 3.0 4.7 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 NDUFA12 PF05071.11 EIW67271.1 - 3.1e-25 88.6 0.7 3.7e-25 88.4 0.5 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Glucosamine_iso PF01182.15 EIW67272.1 - 2.1e-61 207.1 0.0 2.6e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ribosomal_L1 PF00687.16 EIW67273.1 - 4.1e-47 160.3 1.1 4.8e-47 160.1 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NeA_P2 PF12312.3 EIW67275.1 - 0.25 10.5 1.0 0.89 8.7 0.1 1.9 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Fasciclin PF02469.17 EIW67276.1 - 7.3e-16 58.3 0.0 1.6e-09 37.8 0.0 2.7 2 1 0 2 2 2 2 Fasciclin domain Ribosomal_L28 PF00830.14 EIW67277.1 - 2.6e-05 23.9 0.8 5.7e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 Ribosomal L28 family SWIRM PF04433.12 EIW67278.1 - 5.6e-34 116.1 0.0 1.7e-33 114.5 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EIW67278.1 - 3.2e-08 33.5 0.0 7.7e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EIW67278.1 - 5.7e-08 32.1 1.8 9.3e-08 31.4 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 EIW67278.1 - 3e-06 27.2 0.0 6.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sec20 PF03908.8 EIW67279.1 - 4.4e-19 67.9 1.8 4.4e-19 67.9 1.3 2.1 2 0 0 2 2 2 1 Sec20 FTCD_C PF04961.7 EIW67279.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase MSG PF02349.10 EIW67279.1 - 0.16 11.9 2.0 0.47 10.4 1.4 1.8 1 1 0 1 1 1 0 Major surface glycoprotein Ribosomal_S6 PF01250.12 EIW67280.1 - 1.7e-06 27.7 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 HOOK PF05622.7 EIW67281.1 - 4.9e-33 113.9 70.3 8e-20 70.2 36.7 4.1 1 1 2 3 3 3 2 HOOK protein T2SF PF00482.18 EIW67281.1 - 1.7 8.5 7.6 0.58 10.0 1.5 3.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Fcf1 PF04900.7 EIW67282.1 - 5.4e-39 132.3 0.5 5.4e-39 132.3 0.3 1.5 2 0 0 2 2 2 1 Fcf1 Epimerase PF01370.16 EIW67284.1 - 5.6e-14 52.1 0.0 7.8e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW67284.1 - 3.2e-11 42.4 0.0 6e-11 41.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW67284.1 - 6.1e-10 39.3 0.0 9.6e-10 38.7 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW67284.1 - 3.2e-09 36.0 0.0 3.3e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIW67284.1 - 1.8e-08 33.9 0.0 2.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIW67284.1 - 0.0073 16.2 0.0 0.025 14.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase SPX PF03105.14 EIW67285.1 - 7.8e-38 130.8 0.1 3.3e-37 128.7 0.1 1.9 1 1 0 1 1 1 1 SPX domain CitMHS PF03600.11 EIW67285.1 - 1.4e-13 50.1 29.5 2.3e-11 42.8 8.7 2.1 1 1 1 2 2 2 2 Citrate transporter DUF21 PF01595.15 EIW67286.1 - 1.2e-34 119.2 0.0 2e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EIW67286.1 - 7.6e-11 41.6 0.2 0.00025 20.7 0.0 2.9 3 0 0 3 3 3 2 CBS domain SUR7 PF06687.7 EIW67289.1 - 1.3e-14 54.2 19.2 1.8e-14 53.8 13.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family TraS PF10624.4 EIW67289.1 - 0.17 11.4 4.2 2 7.9 3.5 2.1 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS Claudin_2 PF13903.1 EIW67289.1 - 1.9 8.1 16.5 1.7 8.2 10.1 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction VHS PF00790.14 EIW67290.1 - 2.8e-36 124.2 0.0 5e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 VHS domain FYVE PF01363.16 EIW67290.1 - 7.3e-16 57.8 5.4 1.3e-15 56.9 3.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EIW67290.1 - 0.00013 21.2 11.1 0.021 14.3 1.1 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 EIW67290.1 - 0.011 15.6 4.3 0.015 15.1 1.3 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger C1_1 PF00130.17 EIW67290.1 - 0.042 13.5 2.4 0.08 12.6 1.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNA_pol_Rpb1_1 PF04997.7 EIW67291.1 - 2.4e-106 355.8 0.0 3.3e-106 355.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EIW67291.1 - 9.2e-100 333.4 0.0 2.1e-99 332.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EIW67291.1 - 1.3e-67 226.8 0.0 2.4e-67 226.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EIW67291.1 - 8.8e-64 214.6 0.0 1.9e-63 213.6 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EIW67291.1 - 6e-48 162.5 0.1 1.7e-47 161.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EIW67291.1 - 7e-41 139.1 0.8 1.3e-40 138.2 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EIW67291.1 - 1.8e-35 120.9 0.1 3.6e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EIW67291.1 - 3.6e-12 45.2 223.3 0.015 15.3 4.3 16.5 7 3 11 20 20 20 17 RNA polymerase Rpb1 C-terminal repeat IMS PF00817.15 EIW67292.1 - 2.9e-47 160.1 0.0 4.9e-47 159.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EIW67292.1 - 1e-11 44.8 0.0 2.6e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EIW67292.1 - 0.032 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif zf-UBR PF02207.15 EIW67293.1 - 1.1e-14 53.8 5.9 1.1e-14 53.8 4.1 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ELL PF10390.4 EIW67293.1 - 9.4e-09 34.8 0.1 1.5e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL TRAPP PF04051.11 EIW67294.1 - 1.8e-26 92.4 0.0 2.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PSP1 PF04468.7 EIW67295.1 - 2.8e-29 100.9 1.0 5.1e-29 100.0 0.7 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DNA_binding_1 PF01035.15 EIW67296.1 - 6.2e-21 73.9 0.2 6.6e-20 70.6 0.1 2.0 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Lipase_3 PF01764.20 EIW67297.1 - 6e-15 55.0 0.0 1.3e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EIW67297.1 - 0.026 14.4 0.2 0.071 12.9 0.1 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family BRK PF07533.11 EIW67297.1 - 0.046 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 BRK domain Abhydrolase_5 PF12695.2 EIW67297.1 - 0.079 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4449 PF14613.1 EIW67298.1 - 3.3e-30 105.1 2.0 3.3e-30 105.1 1.4 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) Fe-S_biosyn PF01521.15 EIW67299.1 - 8.9e-18 64.2 0.0 1.2e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Voltage_CLC PF00654.15 EIW67300.1 - 1.3e-92 310.6 26.3 2.4e-92 309.6 17.4 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EIW67300.1 - 0.00039 20.1 0.0 0.00084 19.0 0.0 1.6 1 0 0 1 1 1 1 CBS domain DUF2937 PF11157.3 EIW67300.1 - 0.18 11.1 0.3 0.62 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Peptidase_S39 PF02122.10 EIW67300.1 - 3.1 7.0 5.9 0.62 9.3 1.3 1.7 2 0 0 2 2 2 0 Peptidase S39 Atx10homo_assoc PF09759.4 EIW67301.1 - 6.4e-24 83.6 0.0 1.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EIW67301.1 - 0.071 12.9 0.1 18 5.3 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat His_Phos_2 PF00328.17 EIW67302.1 - 8.8e-71 239.0 0.0 1.1e-70 238.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EIW67302.1 - 5.6e-05 22.7 0.0 9.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.17 EIW67302.1 - 0.0078 16.3 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Oxysterol_BP PF01237.13 EIW67303.1 - 5.3e-82 275.1 0.0 6.7e-82 274.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein CHCH PF06747.8 EIW67304.1 - 3.9e-07 29.8 5.1 6.8e-07 29.0 3.5 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EIW67304.1 - 0.02 14.9 1.3 0.049 13.7 0.9 1.6 1 0 0 1 1 1 0 GCK domain DUF946 PF06101.6 EIW67305.1 - 1.3e-11 43.2 3.0 5.3e-09 34.6 1.2 2.1 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) DUF1296 PF06972.6 EIW67307.1 - 0.017 15.0 0.1 0.04 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) MCPVI PF02993.9 EIW67308.1 - 0.83 9.7 6.1 14 5.7 3.1 2.3 2 0 0 2 2 2 0 Minor capsid protein VI DUF2587 PF10759.4 EIW67309.1 - 0.045 13.1 0.1 0.13 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF4201 PF13870.1 EIW67310.1 - 0.015 14.7 1.0 0.024 14.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) SR-25 PF10500.4 EIW67311.1 - 0.0017 17.8 7.8 0.0017 17.8 5.4 2.7 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF2587 PF10759.4 EIW67312.1 - 0.025 13.9 0.1 0.061 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Resolvase PF00239.16 EIW67313.1 - 0.01 15.7 4.8 0.023 14.5 3.4 1.6 1 0 0 1 1 1 0 Resolvase, N terminal domain zf-CCHC PF00098.18 EIW67313.1 - 0.028 14.3 4.3 0.05 13.5 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIW67313.1 - 0.036 13.5 0.2 0.082 12.4 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIW67317.1 - 6.8e-05 22.6 1.3 0.0001 22.0 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 EIW67317.1 - 0.019 14.8 0.5 0.034 14.0 0.1 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_6 PF15288.1 EIW67317.1 - 0.028 14.0 0.6 0.053 13.1 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIW67317.1 - 0.036 13.7 1.1 0.054 13.2 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIW67317.1 - 0.079 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIW67317.1 - 0.084 12.3 1.3 0.14 11.6 0.9 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 EIW67318.1 - 0.00019 21.1 1.3 0.0003 20.5 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW67318.1 - 0.068 12.8 0.5 0.17 11.5 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIW67318.1 - 0.12 12.1 1.3 0.22 11.2 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 EIW67318.1 - 0.18 11.7 2.4 0.32 10.9 1.3 1.7 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF2587 PF10759.4 EIW67319.1 - 0.049 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) P34-Arc PF04045.9 EIW67322.1 - 1.1e-101 339.1 0.0 1.4e-101 338.8 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc polyprenyl_synt PF00348.12 EIW67324.1 - 4.5e-76 255.1 0.0 5.4e-76 254.8 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase TRAM_LAG1_CLN8 PF03798.11 EIW67325.1 - 1.3e-33 116.2 20.4 1.3e-33 116.2 14.1 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EIW67325.1 - 3.8e-10 39.1 0.0 1e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein Clp1 PF06807.9 EIW67326.1 - 3.5e-20 72.5 0.0 1.4e-19 70.6 0.0 1.9 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EIW67326.1 - 1.6e-06 27.8 0.0 8.8e-05 22.2 0.0 3.0 3 1 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EIW67326.1 - 0.013 14.9 0.1 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 EIW67326.1 - 0.018 14.5 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EIW67326.1 - 0.02 14.7 0.1 0.039 13.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW67326.1 - 0.02 15.6 0.1 0.056 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EIW67326.1 - 0.034 14.1 0.1 0.25 11.3 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase T2SE PF00437.15 EIW67326.1 - 0.041 12.7 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 EIW67326.1 - 0.042 13.8 0.1 0.094 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EIW67326.1 - 0.085 12.6 0.5 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 EIW67326.1 - 0.12 12.6 0.1 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW67326.1 - 0.15 12.1 0.0 0.69 10.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain UQ_con PF00179.21 EIW67327.1 - 9.6e-26 89.8 0.0 1.1e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW67327.1 - 3.5e-06 26.8 0.0 3.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIW67327.1 - 0.0099 15.7 0.0 0.02 14.7 0.0 1.6 1 1 1 2 2 2 1 RWD domain FlhC PF05280.6 EIW67327.1 - 0.076 12.4 0.1 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) DUF2077 PF09850.4 EIW67327.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Clat_adaptor_s PF01217.15 EIW67328.1 - 1.5e-55 186.8 3.4 1.7e-55 186.6 2.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.6 EIW67328.1 - 0.024 13.9 0.1 0.044 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) MT-A70 PF05063.9 EIW67329.1 - 1.3e-50 171.3 0.1 3.4e-50 170.0 0.0 1.7 1 1 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 EIW67329.1 - 0.017 15.1 0.0 0.079 12.9 0.0 2.2 2 1 0 3 3 3 0 Methyltransferase domain ATP_bind_3 PF01171.15 EIW67330.1 - 3.1e-15 56.1 0.0 4.7e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 EIW67330.1 - 0.0017 17.7 0.7 0.0017 17.7 0.5 3.0 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.11 EIW67330.1 - 0.021 13.3 0.0 0.033 12.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF2392 PF10288.4 EIW67330.1 - 0.096 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) DUF2616 PF11077.3 EIW67330.1 - 3.3 7.1 5.5 2 7.8 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) G-alpha PF00503.15 EIW67334.1 - 2.9e-107 358.7 1.1 3.6e-107 358.4 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW67334.1 - 2.7e-14 52.7 1.2 2.3e-09 36.7 0.1 2.9 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW67334.1 - 0.00035 19.7 0.8 0.049 12.7 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW67334.1 - 0.00053 19.4 0.3 0.014 14.8 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIW67334.1 - 0.0019 18.6 0.1 2.9 8.4 0.0 2.9 3 1 0 3 3 3 2 Miro-like protein DUF2951 PF11166.3 EIW67334.1 - 0.024 14.4 0.7 0.069 13.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) FtsK_SpoIIIE PF01580.13 EIW67334.1 - 0.035 13.5 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family ORC4_C PF14629.1 EIW67334.1 - 0.037 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus AAA_21 PF13304.1 EIW67334.1 - 0.042 13.8 0.3 0.13 12.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain CoA_trans PF01144.18 EIW67335.1 - 0.17 11.0 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase NARP1 PF12569.3 EIW67336.1 - 9.6e-168 559.1 2.3 1.6e-167 558.3 1.6 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EIW67336.1 - 6.2e-09 35.3 20.7 0.056 13.0 0.0 8.0 8 1 0 9 9 9 3 TPR repeat TPR_16 PF13432.1 EIW67336.1 - 7e-09 36.1 20.2 0.59 10.8 0.1 7.6 8 1 1 9 9 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIW67336.1 - 4.7e-08 32.3 29.7 0.73 9.9 0.0 9.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIW67336.1 - 7.7e-07 29.3 15.7 0.14 12.5 0.0 8.0 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW67336.1 - 1.6e-06 28.1 21.8 6.5 7.6 0.0 10.6 8 2 3 11 11 10 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW67336.1 - 5.8e-06 26.1 11.2 0.06 13.2 0.2 7.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIW67336.1 - 1.8e-05 24.5 6.2 0.29 10.9 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW67336.1 - 0.00063 19.7 8.7 0.29 11.4 0.0 6.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIW67336.1 - 0.003 17.8 12.6 45 4.8 0.0 8.4 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW67336.1 - 0.0056 16.3 7.6 1.8 8.5 0.0 6.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW67336.1 - 0.02 14.5 14.7 13 5.6 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIW67336.1 - 0.04 13.8 0.4 0.5 10.2 0.1 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 EIW67336.1 - 0.18 12.0 9.6 2.3 8.4 0.1 5.1 4 1 0 4 4 4 0 Bacterial transcriptional activator domain TPR_4 PF07721.9 EIW67336.1 - 2.8 8.6 9.2 41 5.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Exo_endo_phos PF03372.18 EIW67338.1 - 2.2e-24 86.7 3.8 2.9e-24 86.3 0.3 2.5 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIW67338.1 - 0.072 12.7 0.2 0.2 11.2 0.1 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF1764 PF08576.5 EIW67339.1 - 3.9e-16 59.6 25.4 9.4e-12 45.6 17.6 3.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) Tmemb_cc2 PF10267.4 EIW67339.1 - 1.2 7.6 11.3 1.4 7.3 7.8 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GEMIN8 PF15348.1 EIW67339.1 - 2.4 8.1 9.4 3.5 7.6 6.5 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 FLO_LFY PF01698.11 EIW67339.1 - 2.4 6.8 9.9 3.4 6.4 6.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein CytochromB561_N PF09786.4 EIW67339.1 - 6.3 5.1 15.7 7.7 4.8 10.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ndc1_Nup PF09531.5 EIW67339.1 - 9.6 4.4 12.8 11 4.3 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UQ_con PF00179.21 EIW67340.1 - 6.4e-48 161.7 0.0 7.7e-48 161.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW67340.1 - 0.00019 21.2 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EIW67340.1 - 0.0092 15.6 0.1 0.017 14.8 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EIW67340.1 - 0.055 13.3 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain Hydrolase_6 PF13344.1 EIW67341.1 - 6.7e-22 77.2 0.0 1.4e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW67341.1 - 5e-21 74.1 0.0 1.8e-20 72.4 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EIW67341.1 - 1.6e-05 25.4 0.0 0.00043 20.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIW67341.1 - 0.0045 17.2 0.0 0.033 14.4 0.0 2.2 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF1748 PF08520.5 EIW67342.1 - 2.4e-23 81.5 0.0 2.7e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) zf-RING_2 PF13639.1 EIW67344.1 - 5.7e-14 51.6 5.1 9e-14 51.0 3.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIW67344.1 - 1.7e-07 31.2 0.5 3.1e-07 30.4 0.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EIW67344.1 - 3.3e-06 27.0 3.8 5.3e-06 26.3 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW67344.1 - 1.2e-05 24.9 1.7 1.9e-05 24.2 1.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW67344.1 - 0.00011 21.8 2.3 0.00017 21.1 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW67344.1 - 0.00012 21.8 1.3 0.00026 20.7 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EIW67344.1 - 0.0013 18.3 1.4 0.0022 17.6 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ABC2_membrane_3 PF12698.2 EIW67344.1 - 0.0037 16.3 0.9 0.0053 15.8 0.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein zf-RING_4 PF14570.1 EIW67344.1 - 0.008 15.7 2.8 0.013 15.0 1.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EIW67344.1 - 0.016 15.1 2.1 0.038 13.9 1.5 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EIW67344.1 - 0.065 13.2 2.5 0.13 12.3 1.7 1.5 1 0 0 1 1 1 0 RING-variant domain DUF1180 PF06679.7 EIW67344.1 - 0.15 11.8 0.1 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Prok-RING_1 PF14446.1 EIW67344.1 - 0.38 10.5 2.2 2.2 8.0 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.1 EIW67344.1 - 0.52 9.8 4.5 5.7 6.5 3.1 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Formyl_trans_N PF00551.14 EIW67345.1 - 6.1e-19 68.2 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EIW67345.1 - 1.2e-11 44.5 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain CBFD_NFYB_HMF PF00808.18 EIW67347.1 - 2.2e-09 37.2 0.0 0.00079 19.4 0.0 2.2 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3819 PF12842.2 EIW67347.1 - 0.027 14.1 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Histone PF00125.19 EIW67347.1 - 0.034 14.2 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 HCV_capsid PF01543.12 EIW67348.1 - 0.077 12.9 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus capsid protein P53_TAD PF08563.6 EIW67348.1 - 0.29 10.2 1.9 0.56 9.3 1.3 1.5 1 0 0 1 1 1 0 P53 transactivation motif EamA PF00892.15 EIW67350.1 - 9.6e-13 48.2 8.1 9.6e-13 48.2 5.6 2.0 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EIW67350.1 - 4.4e-07 30.0 0.4 4.4e-07 30.0 0.3 2.7 3 0 0 3 3 3 1 Multidrug resistance efflux transporter DUF3395 PF11875.3 EIW67351.1 - 1.2e-37 128.9 0.0 2.1e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EIW67351.1 - 4.1e-21 74.4 0.7 1e-20 73.2 0.2 1.9 2 0 0 2 2 2 1 DnaJ domain SIR2 PF02146.12 EIW67352.1 - 7.8e-22 77.8 0.0 5.3e-16 58.8 0.0 2.8 2 1 0 2 2 2 2 Sir2 family PhnA_Zn_Ribbon PF08274.7 EIW67352.1 - 0.023 14.4 1.8 0.044 13.5 1.2 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon EPL1 PF10513.4 EIW67352.1 - 0.092 12.9 1.5 0.18 12.0 1.0 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Transp_cyt_pur PF02133.10 EIW67353.1 - 1.2e-84 284.4 42.5 1.5e-84 284.1 29.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin P12 PF12669.2 EIW67354.1 - 0.08 13.1 0.1 0.08 13.1 0.0 3.2 3 1 0 3 3 3 0 Virus attachment protein p12 family MscS_TM PF12794.2 EIW67354.1 - 0.12 10.9 3.0 1 7.9 0.1 2.7 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 CYSTM PF12734.2 EIW67355.1 - 4 7.6 65.6 1.5e+04 -7.9 45.4 3.5 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance LsmAD PF06741.8 EIW67356.1 - 2.4e-22 78.7 1.2 6e-22 77.5 0.8 1.7 1 0 0 1 1 1 1 LsmAD domain DUF2217 PF10265.4 EIW67357.1 - 3.3 6.3 9.6 4.2 6.0 6.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DNA_pol_viral_N PF00242.12 EIW67357.1 - 8.2 5.3 9.3 10 5.0 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Myc_N PF01056.13 EIW67358.1 - 0.073 12.2 0.9 0.11 11.7 0.1 1.6 2 0 0 2 2 2 0 Myc amino-terminal region SPT6_acidic PF14632.1 EIW67358.1 - 2.3 8.4 10.2 3.3 7.9 7.1 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 TPT PF03151.11 EIW67359.1 - 1.3e-21 76.8 11.6 1.3e-21 76.8 8.0 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EIW67359.1 - 0.00074 19.5 5.8 0.00074 19.5 4.0 2.3 2 0 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 EIW67359.1 - 0.067 12.1 19.1 0.97 8.2 13.2 2.0 1 1 0 1 1 1 0 UAA transporter family L51_S25_CI-B8 PF05047.11 EIW67360.1 - 1.2e-05 24.9 0.0 0.00014 21.4 0.0 2.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Macoilin PF09726.4 EIW67361.1 - 0.73 8.0 7.9 0.83 7.8 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3535 PF12054.3 EIW67363.1 - 4.5e-100 335.3 6.8 4e-96 322.3 1.5 4.9 4 1 0 4 4 4 2 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EIW67363.1 - 4.5e-70 235.8 0.0 7.5e-70 235.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EIW67363.1 - 1.2e-14 52.9 16.6 0.0023 17.8 0.2 10.4 10 0 0 10 10 10 4 HEAT repeat Helicase_C PF00271.26 EIW67363.1 - 2.1e-13 49.9 0.0 5.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 EIW67363.1 - 1e-11 44.9 7.2 0.013 15.7 0.0 8.1 8 1 0 8 8 8 3 HEAT repeats HEAT_EZ PF13513.1 EIW67363.1 - 2.6e-07 30.9 23.0 0.44 11.1 0.1 8.8 10 0 0 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIW67363.1 - 0.0069 16.7 0.0 9.7 6.6 0.0 3.3 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region Claudin_3 PF06653.6 EIW67364.1 - 0.025 14.3 0.5 0.025 14.3 0.4 1.6 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF3210 PF11489.3 EIW67364.1 - 0.066 11.9 0.2 0.082 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) EXOSC1 PF10447.4 EIW67365.1 - 1.3e-19 69.9 1.1 2.1e-19 69.2 0.8 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EIW67365.1 - 0.035 14.2 0.5 1.9 8.6 0.2 2.7 2 0 0 2 2 2 0 S1 RNA binding domain DNA_mis_repair PF01119.14 EIW67366.1 - 4.4e-30 103.5 0.0 7.3e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EIW67366.1 - 2e-14 53.4 0.0 4.3e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIW67366.1 - 2.3e-09 36.9 0.0 1.4e-08 34.4 0.0 2.2 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TIM PF00121.13 EIW67367.1 - 1.4e-91 305.9 0.3 1.6e-91 305.7 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Ribosomal_L22 PF00237.14 EIW67368.1 - 1.5e-18 66.6 0.2 1.9e-18 66.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SAC3_GANP PF03399.11 EIW67369.1 - 7.6e-27 94.1 0.0 1.8e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Peptidase_M32 PF02074.10 EIW67369.1 - 0.86 8.1 2.2 0.63 8.5 0.1 1.8 3 0 0 3 3 3 0 Carboxypeptidase Taq (M32) metallopeptidase Cyclin_N PF00134.18 EIW67370.1 - 4.7e-44 149.0 1.2 2.2e-42 143.6 0.4 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIW67370.1 - 4e-27 94.4 0.0 8e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain UBX PF00789.15 EIW67371.1 - 1.2e-08 34.8 0.0 9.9e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 UBX domain Pex16 PF08610.5 EIW67372.1 - 1.9e-79 267.1 1.2 2.2e-79 266.9 0.8 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RabGAP-TBC PF00566.13 EIW67373.1 - 5.2e-44 150.2 0.1 6.9e-44 149.8 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Acyl_transf_1 PF00698.16 EIW67374.1 - 3.4e-62 210.6 0.2 2.5e-61 207.7 0.0 2.6 4 0 0 4 4 4 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EIW67374.1 - 3.2e-30 104.0 0.3 2.4e-29 101.1 0.0 2.3 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EIW67374.1 - 4.2e-30 103.3 0.8 1.2e-29 101.8 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EIW67374.1 - 1.3e-14 54.0 0.0 7e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase ketoacyl-synt PF00109.21 EIW67375.1 - 3.3e-24 85.7 0.1 5.7e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EIW67375.1 - 5.1e-20 72.2 0.0 8.3e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EIW67375.1 - 1.7e-16 60.1 0.0 4.5e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 EIW67375.1 - 5.7e-13 48.6 0.0 1.6e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.20 EIW67375.1 - 0.00088 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.18 EIW67375.1 - 0.027 13.4 0.0 0.061 12.3 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF2945 PF11160.3 EIW67376.1 - 0.0028 17.4 0.4 0.0047 16.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) Methyltransf_16 PF10294.4 EIW67378.1 - 1.4e-05 24.6 0.0 0.0036 16.7 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EIW67378.1 - 0.002 18.7 0.0 0.0064 17.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW67378.1 - 0.0036 17.7 0.0 0.0096 16.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW67378.1 - 0.0074 16.0 0.0 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW67378.1 - 0.15 12.6 0.1 0.38 11.2 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain NAP PF00956.13 EIW67379.1 - 4.7e-81 271.4 3.7 6.5e-81 271.0 2.6 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Hemerythrin PF01814.18 EIW67380.1 - 2.4e-09 37.4 0.3 3.2e-09 37.0 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Cypo_polyhedrin PF05865.6 EIW67380.1 - 0.076 12.2 0.0 6 6.0 0.0 2.2 1 1 1 2 2 2 0 Cypovirus polyhedrin protein SUR7 PF06687.7 EIW67381.1 - 6.1e-18 65.1 14.3 9.7e-18 64.4 9.9 1.3 1 0 0 1 1 1 1 SUR7/PalI family HMG_box PF00505.14 EIW67382.1 - 4.8e-16 58.7 1.6 4.8e-16 58.7 1.1 2.2 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW67382.1 - 8.8e-13 48.4 1.5 8.8e-13 48.4 1.0 2.5 3 0 0 3 3 3 1 HMG-box domain YABBY PF04690.8 EIW67382.1 - 5.4e-05 23.5 0.2 0.00012 22.3 0.1 1.7 1 0 0 1 1 1 1 YABBY protein CHDNT PF08073.7 EIW67382.1 - 0.002 17.7 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 CHDNT (NUC034) domain Cyclin_N PF00134.18 EIW67383.1 - 2.3e-11 43.3 0.0 6.2e-11 41.9 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain RecO_C PF02565.10 EIW67383.1 - 0.058 13.2 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Recombination protein O C terminal RRM_1 PF00076.17 EIW67384.1 - 2.2e-33 113.6 0.1 9.4e-18 63.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW67384.1 - 1.2e-26 92.4 0.1 4.9e-12 45.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW67384.1 - 8.1e-19 67.2 0.0 1.8e-08 34.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EIW67384.1 - 1e-12 48.1 0.1 3.1e-12 46.5 0.1 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 EIW67384.1 - 0.00015 21.5 0.0 0.00015 21.5 0.0 2.4 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EIW67384.1 - 0.00026 20.6 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EIW67384.1 - 0.63 8.4 65.4 0.91 7.9 45.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 eIF3_subunit PF08597.5 EIW67385.1 - 9.4e-44 149.8 8.8 1.1e-43 149.5 6.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit GOLGA2L5 PF15070.1 EIW67385.1 - 0.0065 15.0 1.1 0.055 11.9 0.7 1.9 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 FAD-SLDH PF12318.3 EIW67385.1 - 0.013 15.2 1.5 0.016 14.9 0.5 1.5 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase U3snoRNP10 PF12397.3 EIW67385.1 - 0.063 13.2 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 Arf PF00025.16 EIW67386.1 - 9.8e-40 135.6 0.0 1.1e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIW67386.1 - 1.9e-18 66.3 0.0 2.3e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW67386.1 - 4.8e-12 46.4 0.0 5.2e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EIW67386.1 - 5.1e-10 38.8 0.0 6.5e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIW67386.1 - 1.9e-07 30.4 0.0 2.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIW67386.1 - 2.5e-06 27.4 0.0 3.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW67386.1 - 6.6e-05 22.4 0.0 0.0027 17.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EIW67386.1 - 0.00044 19.0 0.4 0.0018 17.0 0.1 2.0 2 1 0 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 EIW67386.1 - 0.0047 16.7 0.1 0.94 9.2 0.2 2.2 1 1 1 2 2 2 2 Dynamin family ATP_bind_1 PF03029.12 EIW67386.1 - 0.0082 15.7 0.0 0.21 11.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FAD_binding_7 PF03441.9 EIW67387.1 - 2.3e-61 207.4 0.8 3.2e-61 206.9 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EIW67387.1 - 7.1e-19 68.1 0.0 2.4e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 DNA photolyase Hus1 PF04005.7 EIW67387.1 - 0.23 10.3 0.1 0.36 9.7 0.1 1.2 1 0 0 1 1 1 0 Hus1-like protein GFO_IDH_MocA PF01408.17 EIW67388.1 - 4.3e-14 53.0 0.0 7.7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abi_C PF14355.1 EIW67389.1 - 0.0092 15.8 0.4 0.09 12.7 0.0 2.6 2 0 0 2 2 2 1 Abortive infection C-terminus PapD-like PF14874.1 EIW67390.1 - 0.00091 19.1 0.0 0.56 10.1 0.0 3.7 3 0 0 3 3 3 1 Flagellar-associated PapD-like DUF1090 PF06476.7 EIW67390.1 - 0.065 12.9 2.2 0.18 11.4 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Peptidase_M20 PF01546.23 EIW67391.1 - 4.9e-26 91.3 0.0 7.8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EIW67391.1 - 7.7e-18 63.6 6.1 0.00046 19.9 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat M20_dimer PF07687.9 EIW67391.1 - 1e-12 47.7 0.0 2.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain PQQ_3 PF13570.1 EIW67391.1 - 0.0021 18.2 5.6 2.7 8.4 0.0 4.5 5 0 0 5 5 5 2 PQQ-like domain Amino_oxidase PF01593.19 EIW67392.1 - 5.6e-13 48.7 0.0 9.9e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EIW67392.1 - 1.5e-11 43.8 0.0 6.1e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW67392.1 - 2.2e-11 43.5 0.1 5.6e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW67392.1 - 0.00029 19.8 0.5 0.35 9.6 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EIW67392.1 - 0.0036 17.3 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase PAT1 PF09770.4 EIW67393.1 - 6.1 4.9 30.4 6.3 4.9 21.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 EIW67394.1 - 2.6 5.6 14.6 2.8 5.5 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Nop16 PF09420.5 EIW67396.1 - 1.1e-37 129.6 2.7 1.4e-37 129.2 1.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF740 PF05340.7 EIW67396.1 - 0.0093 14.3 2.5 0.012 13.9 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF740) Cwf_Cwc_15 PF04889.7 EIW67396.1 - 0.028 14.1 1.3 0.028 14.1 0.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein HD_3 PF13023.1 EIW67396.1 - 0.1 12.3 0.2 0.1 12.3 0.2 1.7 2 0 0 2 2 2 0 HD domain RRM_5 PF13893.1 EIW67397.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW67397.1 - 0.13 12.2 0.0 0.82 9.6 0.0 2.3 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cornichon PF03311.9 EIW67398.1 - 2.7e-54 182.7 8.9 3e-54 182.5 6.2 1.0 1 0 0 1 1 1 1 Cornichon protein RabGAP-TBC PF00566.13 EIW67400.1 - 9.7e-50 169.0 0.0 1.4e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TSC22 PF01166.13 EIW67400.1 - 0.0082 16.0 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF4140 PF13600.1 EIW67400.1 - 0.012 16.0 1.2 3 8.3 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) adh_short_C2 PF13561.1 EIW67403.1 - 8e-25 88.0 0.0 1e-24 87.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW67403.1 - 2.3e-24 86.1 0.0 3.2e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW67403.1 - 2.4e-06 27.3 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIW67403.1 - 0.088 12.6 0.6 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SapB_2 PF03489.12 EIW67407.1 - 0.061 13.3 1.2 0.061 13.3 0.8 1.8 2 0 0 2 2 2 0 Saposin-like type B, region 2 Glyco_hydro_31 PF01055.21 EIW67410.1 - 0.037 12.8 0.0 0.051 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Peptidase_M1 PF01433.15 EIW67412.1 - 1.2e-69 235.2 0.0 1.8e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EIW67412.1 - 2.6e-35 121.1 0.0 4.9e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EIW67412.1 - 7.3e-14 51.9 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EIW67412.1 - 0.11 12.4 1.5 1.3 8.9 1.1 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase RPEL PF02755.10 EIW67413.1 - 0.075 12.3 0.3 0.19 11.0 0.2 1.8 1 0 0 1 1 1 0 RPEL repeat ATP-synt_D PF01813.12 EIW67416.1 - 8.4e-69 231.0 0.5 1e-68 230.7 0.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit D WD40 PF00400.27 EIW67417.1 - 2.8e-20 71.3 19.6 2.4e-09 36.7 0.7 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Tim54 PF11711.3 EIW67417.1 - 0.27 9.8 3.3 0.43 9.1 2.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Lin-8 PF03353.10 EIW67417.1 - 1.2 8.2 10.0 2 7.6 7.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SAPS PF04499.10 EIW67417.1 - 2 6.9 5.7 2.8 6.4 3.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CENP-T PF15511.1 EIW67417.1 - 7.6 5.6 26.5 15 4.7 18.4 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RasGEF PF00617.14 EIW67419.1 - 9.1e-54 182.0 0.0 2.2e-53 180.7 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIW67419.1 - 5.7e-24 84.2 0.7 1.3e-23 83.1 0.5 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EIW67419.1 - 2.3e-15 55.6 0.1 7.6e-15 54.0 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIW67419.1 - 8.3e-15 54.0 0.0 2e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIW67419.1 - 1.1e-13 50.4 0.3 2.7e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.21 EIW67419.1 - 0.024 14.4 0.3 3.3 7.6 0.1 2.5 2 0 0 2 2 2 0 WW domain WD40 PF00400.27 EIW67420.1 - 4.6e-71 232.3 7.7 3.1e-13 49.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EIW67420.1 - 1.3e-21 76.5 3.9 1.3e-21 76.5 2.7 1.9 2 0 0 2 2 2 1 Tup N-terminal PD40 PF07676.7 EIW67420.1 - 3.1e-06 26.7 1.1 9.6 5.9 0.0 5.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EIW67420.1 - 2.4e-05 24.1 0.0 0.38 10.4 0.0 3.9 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW67420.1 - 7.8e-05 20.9 1.2 0.22 9.6 0.0 3.3 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIW67420.1 - 0.0001 21.5 0.2 0.38 9.8 0.0 3.3 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EIW67420.1 - 0.003 16.3 0.4 1.4 7.5 0.0 2.9 1 1 2 3 3 3 2 Nup133 N terminal like Gmad1 PF10647.4 EIW67420.1 - 0.003 17.0 0.9 0.01 15.2 0.5 2.0 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 EIW67420.1 - 0.0041 15.4 2.1 1.7 6.8 0.0 3.9 1 1 2 4 4 4 1 Cytochrome D1 heme domain DPPIV_N PF00930.16 EIW67420.1 - 0.013 14.1 0.0 0.18 10.3 0.0 2.8 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF148 PF02520.12 EIW67420.1 - 0.05 13.3 0.8 0.12 12.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF148 Spc7 PF08317.6 EIW67420.1 - 0.077 11.6 0.2 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4558 PF15104.1 EIW67420.1 - 0.24 11.3 3.2 0.59 10.1 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) Proteasome_A_N PF10584.4 EIW67420.1 - 0.27 10.5 8.7 3.8 6.9 0.0 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature TPR_2 PF07719.12 EIW67421.1 - 9.2e-26 87.6 13.9 0.0069 16.2 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 EIW67421.1 - 9.4e-24 82.8 15.5 1.8e-10 40.3 0.2 5.9 4 1 1 7 7 7 4 TPR repeat Apc3 PF12895.2 EIW67421.1 - 1.4e-23 82.8 4.3 6.7e-08 32.5 0.0 5.3 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EIW67421.1 - 2e-20 71.4 10.2 0.00097 18.6 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIW67421.1 - 8.4e-18 64.0 17.5 1.6e-07 31.1 0.4 6.3 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIW67421.1 - 6.1e-16 58.6 17.5 7.6e-06 26.4 0.1 6.2 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW67421.1 - 2.1e-14 52.1 2.4 0.15 11.8 0.1 8.0 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW67421.1 - 6.5e-10 38.7 16.5 0.0024 18.3 0.1 7.7 3 1 5 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW67421.1 - 2.5e-07 30.3 4.6 0.26 11.5 0.1 6.5 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW67421.1 - 4.1e-06 26.1 13.4 0.11 12.3 0.0 6.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW67421.1 - 1e-05 25.7 8.6 0.33 11.2 0.0 6.1 4 1 1 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 EIW67421.1 - 0.00071 19.3 4.2 4.9 7.0 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIW67421.1 - 0.0019 18.0 16.5 3.5 7.6 0.2 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW67421.1 - 0.0045 17.3 6.3 2.8 8.5 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIW67421.1 - 0.045 13.5 16.3 0.26 11.1 0.7 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat SipA PF09052.5 EIW67424.1 - 0.18 10.1 0.9 0.25 9.7 0.6 1.1 1 0 0 1 1 1 0 Salmonella invasion protein A Pkinase PF00069.20 EIW67425.1 - 1.3e-42 145.7 0.4 1.6e-23 83.2 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67425.1 - 5e-13 48.7 0.3 1.6e-09 37.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ShlB PF03865.8 EIW67425.1 - 0.051 12.3 0.2 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Pox_ser-thr_kin PF05445.6 EIW67425.1 - 0.27 9.9 0.0 0.41 9.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNA_pol_A_bac PF01000.21 EIW67427.1 - 1.8e-22 79.6 0.0 3.3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EIW67427.1 - 7.3e-10 37.8 0.0 9.6e-10 37.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1998 PF09369.5 EIW67427.1 - 0.0072 16.8 0.4 0.015 15.8 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Pico_P2A PF00947.14 EIW67427.1 - 0.037 13.8 0.1 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 Picornavirus core protein 2A Egg_lysin PF01303.12 EIW67428.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) Kinesin PF00225.18 EIW67429.1 - 2.8e-82 276.1 0.0 1.9e-80 270.1 0.0 3.5 3 2 0 3 3 3 1 Kinesin motor domain TetR_C_5 PF08360.6 EIW67429.1 - 0.028 14.4 0.5 0.053 13.4 0.4 1.4 1 0 0 1 1 1 0 QacR-like protein, C-terminal region Nop14 PF04147.7 EIW67429.1 - 3 5.6 34.6 0.0084 14.1 17.0 1.8 2 0 0 2 2 2 0 Nop14-like family Amidohydro_4 PF13147.1 EIW67430.1 - 1e-13 51.9 0.0 9.2e-12 45.5 0.0 2.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EIW67430.1 - 2.9e-11 43.0 0.3 1.2e-07 31.4 0.0 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EIW67430.1 - 1.7e-08 34.1 0.1 3.3e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 EIW67430.1 - 6.7e-08 32.5 0.1 1.9e-05 24.4 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Glyco_transf_8 PF01501.15 EIW67431.1 - 9.3e-09 34.9 0.0 2.2e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 CLASP_N PF12348.3 EIW67432.1 - 5.4e-17 61.9 0.0 8.5e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 CLASP N terminal Glyoxal_oxid_N PF07250.6 EIW67434.1 - 6.2e-47 159.7 0.5 1.6e-44 151.8 0.1 2.9 3 0 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIW67434.1 - 1.1e-18 67.1 0.0 2.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIW67434.1 - 0.0017 18.0 12.9 0.44 10.3 0.0 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Serglycin PF04360.7 EIW67434.1 - 0.002 17.8 4.5 0.0042 16.8 3.1 1.5 1 0 0 1 1 1 1 Serglycin Kelch_6 PF13964.1 EIW67434.1 - 0.2 11.8 5.7 21 5.4 0.0 4.8 6 0 0 6 6 6 0 Kelch motif DBR1 PF05011.8 EIW67435.1 - 2.7e-26 92.2 0.0 8.4e-18 64.6 0.0 2.3 2 0 0 2 2 2 2 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EIW67435.1 - 5.3e-09 35.7 1.2 8.6e-09 35.0 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cytochrom_B561 PF03188.11 EIW67436.1 - 1.4e-08 34.6 10.6 2.2e-08 34.0 7.1 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 UAA PF08449.6 EIW67436.1 - 0.058 12.2 0.8 0.23 10.3 0.0 2.1 2 1 1 3 3 3 0 UAA transporter family WH1 PF00568.18 EIW67437.1 - 1.3e-20 73.1 0.1 2e-20 72.5 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 EIW67437.1 - 1.2e-07 32.0 0.0 3.6e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 EIW67437.1 - 0.0013 18.3 0.1 0.0038 16.7 0.1 1.8 1 0 0 1 1 1 1 WH2 motif DCP1 PF06058.8 EIW67437.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family DUF490 PF04357.8 EIW67437.1 - 0.19 10.7 0.7 0.41 9.7 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF490) F-box-like PF12937.2 EIW67438.1 - 0.039 13.6 2.7 2.4 7.9 0.4 2.5 2 0 0 2 2 2 0 F-box-like HTH_9 PF08221.6 EIW67439.1 - 9.9e-16 57.3 5.1 7.6e-14 51.3 0.9 3.2 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 EIW67439.1 - 5.9e-14 52.2 0.0 1e-11 44.9 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 TrmB PF01978.14 EIW67439.1 - 0.031 13.9 2.2 2.9 7.6 0.0 3.5 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 EIW67439.1 - 0.044 13.2 0.0 7 6.2 0.0 3.3 3 0 0 3 3 3 0 TFIIE alpha subunit HTH_20 PF12840.2 EIW67439.1 - 0.1 12.3 1.8 12 5.7 0.1 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.5 EIW67439.1 - 8.4 6.0 9.4 1 9.0 1.9 2.9 3 1 1 4 4 4 0 IclR helix-turn-helix domain Glyco_trans_1_4 PF13692.1 EIW67440.1 - 2.6e-13 50.2 0.1 2.2e-12 47.2 0.0 2.6 3 1 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIW67440.1 - 8e-08 32.5 1.0 8e-08 32.5 0.7 2.3 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 EIW67440.1 - 0.0016 17.9 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EIW67440.1 - 0.0024 18.1 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Mago-bind PF09282.5 EIW67441.1 - 2.4e-11 42.9 2.9 4.6e-11 42.0 0.8 2.2 2 0 0 2 2 2 1 Mago binding Glyco_hydro_47 PF01532.15 EIW67442.1 - 4.9e-152 506.7 0.0 5.5e-152 506.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_63 PF03200.11 EIW67443.1 - 7.6e-09 33.9 3.9 1.5e-06 26.3 0.4 4.1 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase ATP-synt_10 PF05176.9 EIW67444.1 - 1.9e-63 214.0 0.0 2.1e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein MTBP_mid PF14919.1 EIW67444.1 - 0.018 13.7 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 MDM2-binding Peptidase_M16 PF00675.15 EIW67445.1 - 3.6e-38 130.6 0.0 5.2e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIW67445.1 - 4.6e-28 98.1 0.0 2.2e-27 95.9 0.0 2.0 2 1 1 3 3 3 1 Peptidase M16 inactive domain ABC_tran PF00005.22 EIW67448.1 - 5.9e-16 59.0 0.1 3.3e-15 56.5 0.1 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW67448.1 - 2e-11 44.3 0.9 9.3e-05 22.5 0.2 2.3 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 EIW67448.1 - 1.3e-06 27.7 0.0 0.036 13.1 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EIW67448.1 - 0.00014 21.2 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIW67448.1 - 0.00024 20.5 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EIW67448.1 - 0.0026 17.2 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EIW67448.1 - 0.0031 17.5 0.1 0.0066 16.4 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EIW67448.1 - 0.011 16.5 1.4 0.021 15.6 1.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW67448.1 - 0.014 14.5 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EIW67448.1 - 0.025 14.9 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EIW67448.1 - 0.031 14.7 0.0 0.059 13.8 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein MutS_V PF00488.16 EIW67448.1 - 0.042 13.2 0.0 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 MutS domain V MobB PF03205.9 EIW67448.1 - 0.043 13.5 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EIW67448.1 - 0.043 13.7 0.1 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EIW67448.1 - 0.049 12.8 0.1 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.13 EIW67448.1 - 0.08 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EIW67448.1 - 0.087 12.7 0.2 0.29 11.0 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_13 PF13166.1 EIW67448.1 - 0.093 11.1 0.1 0.15 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EIW67448.1 - 0.097 12.1 0.1 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EIW67448.1 - 0.098 12.7 0.4 0.3 11.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 EIW67448.1 - 0.12 11.6 0.1 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 EIW67448.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EIW67448.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Dynamin family ATP-synt_ab PF00006.20 EIW67448.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EIW67448.1 - 2.3 8.5 4.8 0.18 12.0 0.2 1.7 2 1 0 2 2 1 0 AAA domain DASH_Dad1 PF08649.5 EIW67450.1 - 6.6e-20 70.5 0.1 8.2e-20 70.2 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 IU_nuc_hydro PF01156.14 EIW67451.1 - 8.2e-58 196.0 0.0 1.1e-57 195.7 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Elong_Iki1 PF10483.4 EIW67452.1 - 2.3e-08 33.7 0.1 9.2e-08 31.7 0.0 1.9 1 1 0 1 1 1 1 Elongator subunit Iki1 ArfGap PF01412.13 EIW67453.1 - 6e-38 129.2 0.1 6.8e-38 129.0 0.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF2635 PF10948.3 EIW67453.1 - 0.097 11.9 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Auto_anti-p27 PF06677.7 EIW67454.1 - 1.1e-11 44.2 4.2 5.8e-06 25.9 0.5 2.8 2 1 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) AMP-binding PF00501.23 EIW67455.1 - 7.4e-33 113.5 0.0 1.6e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW67455.1 - 0.12 13.3 0.4 1.1 10.2 0.0 2.8 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain UreF PF01730.11 EIW67456.1 - 2.8e-12 46.9 0.0 4.6e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 UreF CPSase_L_D2 PF02786.12 EIW67457.1 - 8.8e-111 368.2 0.2 6.5e-82 273.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.16 EIW67457.1 - 1.2e-44 151.4 0.0 2.4e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.23 EIW67457.1 - 2.3e-44 151.1 0.0 9.8e-44 149.1 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EIW67457.1 - 1.2e-43 147.7 0.0 8.4e-42 141.7 0.0 3.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_chain PF00289.17 EIW67457.1 - 7.2e-42 141.9 0.0 6.2e-20 71.3 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EIW67457.1 - 9.7e-41 138.3 0.2 2e-40 137.3 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 EIW67457.1 - 1.6e-37 128.7 0.0 7.5e-37 126.6 0.0 2.2 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EIW67457.1 - 8.4e-35 120.1 0.1 4e-21 75.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIW67457.1 - 6e-19 67.9 0.2 2.6e-08 32.9 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EIW67457.1 - 1.9e-18 66.1 0.0 9.7e-18 63.8 0.0 2.4 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.17 EIW67457.1 - 2.7e-15 56.1 0.1 6.8e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIW67457.1 - 2e-13 50.2 0.3 3.6e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 EIW67457.1 - 5.2e-06 26.0 0.0 0.00059 19.3 0.0 2.7 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EIW67457.1 - 5e-05 23.2 0.1 0.33 10.8 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 EIW67457.1 - 0.039 13.4 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family DAHP_synth_1 PF00793.15 EIW67457.1 - 0.15 10.7 0.0 0.31 9.7 0.0 1.4 1 0 0 1 1 1 0 DAHP synthetase I family Pro_dh PF01619.13 EIW67458.1 - 6.1e-28 97.7 0.0 9.2e-20 70.8 0.0 2.2 2 0 0 2 2 2 2 Proline dehydrogenase MarR_2 PF12802.2 EIW67458.1 - 0.05 13.2 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 MarR family Transp_cyt_pur PF02133.10 EIW67459.1 - 6.7e-67 225.9 43.0 1.4e-66 224.9 29.8 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin zf-CCHC_2 PF13696.1 EIW67460.1 - 0.027 13.9 0.2 0.068 12.6 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIW67460.1 - 0.063 13.2 11.2 0.11 12.4 2.5 2.5 2 0 0 2 2 2 0 Zinc knuckle Resolvase PF00239.16 EIW67460.1 - 0.26 11.1 7.3 0.031 14.1 1.0 2.4 3 0 0 3 3 3 0 Resolvase, N terminal domain OTU PF02338.14 EIW67461.1 - 2.9e-12 47.2 0.0 6.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease zf-CCHC PF00098.18 EIW67463.1 - 0.0009 19.0 1.9 0.0015 18.3 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW67463.1 - 0.028 14.1 0.1 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle SNF2_N PF00176.18 EIW67468.1 - 5e-58 196.2 0.1 7.8e-58 195.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EIW67468.1 - 1.3e-07 31.2 0.9 0.0001 21.8 0.0 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 EIW67468.1 - 6.3e-05 22.5 0.0 0.00017 21.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-PHD-like PF15446.1 EIW67468.1 - 9.4e-05 21.7 9.3 0.00078 18.7 1.5 2.5 2 1 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD PF00628.24 EIW67468.1 - 0.41 10.3 19.3 0.2 11.3 2.0 4.1 4 1 0 4 4 4 0 PHD-finger SSB PF00436.20 EIW67469.1 - 0.00065 19.5 0.0 0.0016 18.2 0.0 1.6 1 1 0 1 1 1 1 Single-strand binding protein family Complex1_51K PF01512.12 EIW67471.1 - 9.1e-49 165.0 0.0 1.4e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EIW67471.1 - 4.4e-21 73.7 1.3 9e-21 72.7 0.9 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EIW67471.1 - 1.3e-07 31.4 0.0 3.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DUF423 PF04241.10 EIW67473.1 - 2e-14 53.2 7.2 5.4e-07 29.4 0.0 3.0 2 1 2 4 4 4 2 Protein of unknown function (DUF423) MS_channel PF00924.13 EIW67473.1 - 0.0016 17.8 0.3 0.0032 16.8 0.2 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel PHD PF00628.24 EIW67474.1 - 1.2e-08 34.5 11.4 1.9e-08 33.8 7.9 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EIW67474.1 - 5.6e-08 33.0 0.3 4.5e-07 30.0 0.2 2.2 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EIW67474.1 - 0.0029 17.7 1.4 0.0055 16.8 0.9 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain DUF4582 PF15189.1 EIW67474.1 - 0.034 13.3 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) zf-HC5HC2H_2 PF13832.1 EIW67474.1 - 0.14 12.1 2.4 0.25 11.3 1.7 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain YTH PF04146.10 EIW67475.1 - 1.2e-44 151.2 0.0 4.1e-44 149.5 0.0 1.8 1 1 0 1 1 1 1 YT521-B-like domain Usp PF00582.21 EIW67476.1 - 4.6e-19 68.9 1.4 9.7e-19 67.9 0.1 2.1 2 0 0 2 2 2 1 Universal stress protein family MFS_1 PF07690.11 EIW67477.1 - 1.1e-26 93.4 37.4 1.2e-21 76.8 15.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW67477.1 - 2.4e-05 23.1 12.0 2.4e-05 23.1 8.3 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3188 PF11384.3 EIW67477.1 - 0.015 14.8 4.9 0.15 11.6 1.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3188) Na_H_Exchanger PF00999.16 EIW67478.1 - 1.3e-56 191.8 27.6 1.6e-56 191.5 19.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EIW67478.1 - 2.4 8.1 7.5 0.57 10.1 0.2 3.1 3 0 0 3 3 3 0 YrhC-like protein zf-Mss51 PF13824.1 EIW67496.1 - 2.2e-19 69.0 1.8 3.6e-19 68.3 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1610 PF07754.6 EIW67496.1 - 0.12 12.5 1.4 0.26 11.4 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Ank_2 PF12796.2 EIW67497.1 - 1.3e-07 31.8 0.0 2.2e-06 27.9 0.0 2.2 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIW67497.1 - 4.9e-07 29.2 0.4 0.0046 16.6 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EIW67497.1 - 4.2e-05 23.9 0.2 0.00021 21.7 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW67497.1 - 0.00047 20.1 0.0 12 6.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIW67497.1 - 0.031 14.5 0.1 1.3 9.3 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Pkinase PF00069.20 EIW67498.1 - 7e-70 235.1 0.0 8.1e-70 234.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67498.1 - 7.3e-37 126.8 0.0 9.1e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW67498.1 - 4.3e-12 45.5 0.0 1.5e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIW67498.1 - 0.027 13.5 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW67498.1 - 0.081 12.6 0.2 0.25 11.0 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_S2 PF00318.15 EIW67500.1 - 1e-43 149.0 0.0 1.9e-41 141.6 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S2 DUF4599 PF15371.1 EIW67500.1 - 0.11 12.5 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) Peptidase_M16_C PF05193.16 EIW67501.1 - 3.4e-21 75.7 0.0 2.4e-11 43.6 0.0 3.6 3 0 0 3 3 3 3 Peptidase M16 inactive domain M16C_assoc PF08367.6 EIW67501.1 - 6.5e-09 34.9 3.1 1e-06 27.7 0.0 3.4 3 0 0 3 3 3 2 Peptidase M16C associated Peptidase_M16 PF00675.15 EIW67501.1 - 2.1e-07 30.8 0.0 6.4e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Rad4 PF03835.10 EIW67502.1 - 4.5e-34 116.9 4.8 3.7e-33 113.9 0.4 2.6 2 0 0 2 2 2 2 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EIW67502.1 - 6e-26 89.9 0.0 1.1e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EIW67502.1 - 8.3e-18 63.6 0.8 1.3e-16 59.8 0.0 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EIW67502.1 - 9.3e-14 51.4 3.1 9.3e-14 51.4 2.1 3.1 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EIW67502.1 - 5.5e-05 23.3 0.2 0.00055 20.1 0.1 2.5 1 1 0 1 1 1 1 Transglutaminase-like superfamily DER1 PF04511.10 EIW67503.1 - 1e-50 172.0 5.2 1.2e-50 171.7 3.6 1.0 1 0 0 1 1 1 1 Der1-like family Sas10 PF09368.5 EIW67504.1 - 3.5e-22 78.3 6.6 3.5e-22 78.3 4.6 3.5 3 1 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EIW67504.1 - 0.0017 18.4 0.0 0.0064 16.6 0.0 2.0 1 0 0 1 1 1 1 Sas10/Utp3/C1D family zf-U1 PF06220.7 EIW67505.1 - 1.1e-11 44.0 0.9 2e-11 43.2 0.6 1.5 1 0 0 1 1 1 1 U1 zinc finger DUF4152 PF13680.1 EIW67505.1 - 0.027 13.4 0.5 0.59 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4152) DUF3022 PF11226.3 EIW67512.1 - 0.094 12.6 0.2 15 5.5 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3022) zf-H2C2 PF09337.5 EIW67513.1 - 0.016 14.6 3.0 0.031 13.6 2.1 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger TFIIA PF03153.8 EIW67514.1 - 3e-34 119.5 2.9 2.8e-27 96.5 1.3 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit GNAT_acetyltr_2 PF13718.1 EIW67515.1 - 1.5e-72 243.0 0.0 2.6e-72 242.3 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EIW67515.1 - 4.7e-64 215.2 0.0 1.2e-63 213.9 0.0 1.7 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EIW67515.1 - 7e-38 128.2 0.0 1.7e-37 126.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EIW67515.1 - 9.1e-26 89.9 0.2 3.3e-25 88.1 0.1 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 EIW67515.1 - 0.011 15.7 0.0 0.034 14.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW67515.1 - 0.034 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain C1_1 PF00130.17 EIW67516.1 - 1.5e-06 27.7 14.6 2.3e-05 24.0 2.0 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EIW67516.1 - 0.77 9.5 22.7 0.18 11.4 4.9 2.5 2 0 0 2 2 2 0 PHD-finger Clathrin PF00637.15 EIW67517.1 - 8.4e-19 67.5 0.2 1e-14 54.3 0.1 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 EIW67517.1 - 1.2e-12 47.4 0.1 2.7e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal C1_1 PF00130.17 EIW67517.1 - 0.1 12.3 3.0 0.26 11.0 2.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 EIW67517.1 - 0.26 11.0 6.3 0.47 10.2 4.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_1 PF14446.1 EIW67517.1 - 0.4 10.4 4.3 0.8 9.4 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 EIW67517.1 - 0.56 10.2 6.8 1.1 9.3 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW67517.1 - 3.8 7.4 7.4 8.2 6.3 5.1 1.6 1 0 0 1 1 1 0 Ring finger domain PPTA PF01239.17 EIW67518.1 - 1.6e-43 144.2 12.4 1.8e-08 33.3 0.3 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat MetW PF07021.7 EIW67518.1 - 0.00065 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW zf-CCHC PF00098.18 EIW67519.1 - 0.00068 19.4 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW67519.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW67519.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW67520.1 - 0.11 11.8 0.1 0.28 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Daxx PF03344.10 EIW67522.1 - 0.066 11.7 2.5 0.081 11.4 1.7 1.2 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 EIW67522.1 - 0.67 8.9 9.1 0.9 8.5 6.3 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EIW67522.1 - 1.5 6.6 5.6 1.8 6.3 3.9 1.0 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.18 EIW67523.1 - 0.00023 20.9 1.3 0.00035 20.3 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW67523.1 - 0.057 13.0 0.5 0.2 11.3 0.4 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIW67523.1 - 0.12 12.1 1.3 0.25 11.0 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3716 PF12511.3 EIW67524.1 - 0.086 12.4 5.5 0.15 11.7 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) DUF221 PF02714.10 EIW67528.1 - 2e-85 286.5 17.4 2e-85 286.5 12.1 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIW67528.1 - 1.7e-28 99.1 1.0 6.2e-28 97.3 0.7 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EIW67528.1 - 4.9e-17 61.6 0.0 1e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EIW67528.1 - 9.2e-07 29.3 1.2 2.3e-06 28.0 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) DUF1282 PF06930.7 EIW67528.1 - 0.0085 15.7 2.0 0.0085 15.7 1.4 4.3 4 1 1 5 5 5 2 Protein of unknown function (DUF1282) Cyt-b5 PF00173.23 EIW67529.1 - 4.4e-20 71.2 0.0 5.9e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA_23 PF13476.1 EIW67530.1 - 1.2e-26 94.3 6.8 1.2e-26 94.3 4.7 7.4 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.1 EIW67530.1 - 1.1e-11 45.2 7.4 1.7e-05 24.9 0.1 3.8 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EIW67530.1 - 5.6e-10 38.8 0.1 5.6e-10 38.8 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EIW67530.1 - 1e-09 38.1 0.1 6.9e-09 35.5 0.0 2.4 1 1 1 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EIW67530.1 - 2.5e-06 26.8 15.8 2.5e-06 26.8 11.0 4.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_13 PF13166.1 EIW67530.1 - 0.00013 20.5 0.0 0.00013 20.5 0.0 6.8 3 2 2 6 6 6 2 AAA domain AAA_29 PF13555.1 EIW67530.1 - 0.00038 19.9 0.0 0.003 17.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EIW67530.1 - 0.01 15.2 2.1 0.23 10.8 0.0 3.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 EIW67530.1 - 0.082 13.4 3.7 0.14 12.6 0.0 3.4 3 1 0 3 3 3 0 Miro-like protein AAA_19 PF13245.1 EIW67530.1 - 0.13 12.0 1.1 0.5 10.1 0.0 2.6 3 0 0 3 3 3 0 Part of AAA domain TraC_F_IV PF11130.3 EIW67531.1 - 0.029 13.7 0.0 2.4 7.5 0.0 2.2 1 1 1 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer zf-CCHC PF00098.18 EIW67533.1 - 7.7e-05 22.4 3.1 7.7e-05 22.4 2.1 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW67533.1 - 9e-05 22.1 1.2 0.00022 20.8 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EIW67533.1 - 0.14 11.6 2.7 0.24 10.9 1.8 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger tRNA-synt_1g PF09334.6 EIW67533.1 - 0.33 9.5 5.6 0.42 9.2 3.9 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (M) zf-C4pol PF14260.1 EIW67533.1 - 0.35 10.9 2.5 0.99 9.4 0.1 2.2 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta FliD_N PF02465.13 EIW67533.1 - 0.69 10.3 6.2 0.5 10.7 0.9 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4376 PF14301.1 EIW67533.1 - 1.9 8.6 8.2 8.1 6.6 0.3 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4376) Resolvase PF00239.16 EIW67534.1 - 0.007 16.2 4.9 0.013 15.3 3.4 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC PF00098.18 EIW67534.1 - 0.025 14.5 4.3 0.042 13.7 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIW67534.1 - 0.041 13.3 0.2 0.07 12.6 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Fork_head_N PF08430.7 EIW67538.1 - 0.023 15.0 13.7 0.023 15.0 9.5 3.4 2 1 0 2 2 2 0 Forkhead N-terminal region DUF3759 PF12585.3 EIW67538.1 - 0.086 12.7 0.1 0.086 12.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3759) Malic_M PF03949.10 EIW67540.1 - 1.2e-80 270.7 0.0 1.5e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIW67540.1 - 2.4e-62 209.7 0.0 3.9e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF1368 PF07112.6 EIW67541.1 - 0.033 12.7 0.2 0.045 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) Borealin PF10512.4 EIW67541.1 - 0.11 12.4 0.1 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 HORMA PF02301.13 EIW67542.1 - 6.2e-15 55.2 0.0 7.7e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Ax_dynein_light PF10211.4 EIW67542.1 - 0.11 12.2 0.0 4.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain EPL1 PF10513.4 EIW67543.1 - 1.8e-28 99.7 0.8 1.8e-28 99.7 0.5 4.1 3 2 0 3 3 3 2 Enhancer of polycomb-like DUF1762 PF08574.5 EIW67544.1 - 6.8e-05 23.2 22.7 0.0013 19.0 15.7 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1762) SR-25 PF10500.4 EIW67544.1 - 2.3 7.6 8.2 0.06 12.8 0.5 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ThiF PF00899.16 EIW67545.1 - 4.1e-34 117.3 0.0 6.8e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family 3HCDH_N PF02737.13 EIW67545.1 - 0.012 15.2 0.0 0.043 13.4 0.0 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 EIW67545.1 - 0.016 14.1 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EIW67545.1 - 0.062 13.5 0.0 0.17 12.1 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EIW67545.1 - 0.082 12.2 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Tfb2 PF03849.9 EIW67546.1 - 1e-88 297.4 0.1 1.4e-88 297.0 0.1 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EIW67546.1 - 0.026 14.2 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain AF1Q PF15017.1 EIW67550.1 - 0.019 14.8 4.4 0.041 13.7 3.1 1.6 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator CENP-B_dimeris PF09026.5 EIW67550.1 - 0.023 14.9 7.0 0.041 14.1 4.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ADH_zinc_N_2 PF13602.1 EIW67551.1 - 1.6e-08 35.4 0.5 3.6e-08 34.3 0.3 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DcpS_C PF11969.3 EIW67552.1 - 2.3e-28 98.7 0.4 4.1e-28 97.9 0.3 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EIW67552.1 - 0.00019 21.7 0.2 0.00039 20.7 0.1 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.18 EIW67552.1 - 0.081 13.4 2.8 0.098 13.2 1.1 1.8 2 0 0 2 2 2 0 HIT domain GalP_UDP_tr_C PF02744.12 EIW67552.1 - 2.2 7.7 7.2 0.76 9.2 2.6 2.0 2 1 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain INCENP_ARK-bind PF03941.10 EIW67553.1 - 1.3e-15 56.9 0.1 1.8e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Sigma70_r1_2 PF00140.15 EIW67553.1 - 0.0015 18.1 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 DUF3635 PF12330.3 EIW67554.1 - 1.4e-10 41.0 0.1 3.1e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 EIW67554.1 - 0.00032 19.9 0.0 0.0012 18.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Mitofilin PF09731.4 EIW67554.1 - 0.18 10.4 3.8 0.25 9.9 2.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ribosomal_S24e PF01282.14 EIW67555.1 - 8.5e-32 108.8 0.1 8.5e-32 108.8 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S24e Pyrid_oxidase_2 PF13883.1 EIW67556.1 - 2.4e-35 121.7 0.0 2.9e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-HIT PF04438.11 EIW67558.1 - 1.1e-05 24.9 12.0 1.7e-05 24.3 8.3 1.2 1 0 0 1 1 1 1 HIT zinc finger Cullin PF00888.17 EIW67559.1 - 7.3e-168 559.7 14.4 1e-167 559.3 10.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EIW67559.1 - 6e-27 93.2 1.5 1.4e-26 92.0 1.1 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 EIW67559.1 - 0.0059 16.6 2.4 5.4 7.1 0.0 4.0 2 1 1 3 3 3 2 Penicillinase repressor Beach PF02138.13 EIW67560.1 - 2.5e-97 325.5 0.0 3.4e-97 325.1 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EIW67560.1 - 1.3e-12 47.5 0.0 2.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EIW67560.1 - 4.7e-10 38.9 0.3 6e-08 32.2 0.1 3.5 2 0 0 2 2 2 1 WD domain, G-beta repeat FYVE PF01363.16 EIW67560.1 - 0.00043 20.1 4.8 0.0011 18.7 3.2 1.7 1 1 0 1 1 1 1 FYVE zinc finger Orthopox_C10L PF07020.6 EIW67560.1 - 0.11 13.0 0.6 0.28 11.7 0.4 1.6 1 0 0 1 1 1 0 Orthopoxvirus C10L protein zf-AN1 PF01428.11 EIW67560.1 - 0.37 10.6 4.5 0.94 9.4 3.1 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger DUF1005 PF06219.7 EIW67563.1 - 1.4 7.4 7.8 1.6 7.3 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) ABC2_membrane_3 PF12698.2 EIW67564.1 - 0.073 12.0 9.7 0.12 11.3 6.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Tim54 PF11711.3 EIW67564.1 - 0.075 11.6 2.7 0.12 10.9 1.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Adeno_E3_CR2 PF02439.10 EIW67564.1 - 6.7 6.3 7.5 15 5.1 5.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF287 PF03384.9 EIW67566.1 - 0.19 11.9 0.6 0.39 10.9 0.4 1.4 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 RVP_2 PF08284.6 EIW67567.1 - 0.00075 19.4 0.0 0.00099 19.0 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIW67567.1 - 0.06 12.9 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease Resolvase PF00239.16 EIW67571.1 - 0.0053 16.6 2.6 0.0098 15.7 1.8 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC_2 PF13696.1 EIW67571.1 - 0.026 13.9 0.2 0.056 12.9 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIW67571.1 - 0.034 14.0 4.3 0.034 14.0 3.0 1.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EIW67572.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW67572.1 - 0.31 11.2 5.9 0.09 13.0 2.0 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF2587 PF10759.4 EIW67573.1 - 0.041 13.2 0.1 0.12 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW67574.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW67574.1 - 0.33 11.1 8.4 0.087 13.0 3.7 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW67574.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Cwf_Cwc_15 PF04889.7 EIW67575.1 - 3.4e-75 252.9 16.8 3.8e-75 252.7 11.6 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 EIW67575.1 - 0.0038 16.5 15.9 0.0055 16.0 11.0 1.3 1 0 0 1 1 1 1 SDA1 SGT1 PF07093.6 EIW67575.1 - 0.04 12.3 10.3 0.044 12.1 7.1 1.1 1 0 0 1 1 1 0 SGT1 protein SAPS PF04499.10 EIW67575.1 - 0.13 10.8 5.8 0.15 10.6 4.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PA26 PF04636.8 EIW67575.1 - 0.25 10.0 4.8 0.33 9.6 3.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Nop14 PF04147.7 EIW67575.1 - 0.29 9.0 19.4 0.35 8.7 13.5 1.1 1 0 0 1 1 1 0 Nop14-like family HNF-1_N PF04814.8 EIW67575.1 - 0.33 11.0 5.9 1.2 9.2 4.7 1.6 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF342 PF03961.8 EIW67575.1 - 0.54 8.6 4.6 0.7 8.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CDC45 PF02724.9 EIW67575.1 - 1.1 7.2 18.6 1.5 6.8 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Phyto_Pns9_10 PF05878.6 EIW67575.1 - 1.2 8.0 7.0 1.9 7.4 4.8 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Sporozoite_P67 PF05642.6 EIW67575.1 - 2.3 5.9 9.2 3 5.5 6.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hid1 PF12722.2 EIW67575.1 - 3.9 5.0 9.5 5.1 4.6 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NOA36 PF06524.7 EIW67575.1 - 6.6 5.9 8.5 9.2 5.4 5.9 1.3 1 0 0 1 1 1 0 NOA36 protein Rtf2 PF04641.7 EIW67575.1 - 6.7 5.8 11.9 11 5.1 8.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1510 PF07423.6 EIW67575.1 - 7.4 5.8 17.3 13 5.1 12.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIF_alpha PF05793.7 EIW67575.1 - 8.5 4.6 26.6 6 5.1 17.5 1.6 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FA_desaturase PF00487.19 EIW67576.1 - 1.8e-11 43.9 22.1 2.8e-11 43.3 15.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase BRE PF06113.7 EIW67576.1 - 0.031 13.3 0.3 0.046 12.7 0.2 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) LTP_2 PF14368.1 EIW67577.1 - 0.023 14.8 0.7 0.043 13.9 0.5 1.5 1 0 0 1 1 1 0 Probable lipid transfer GARS_A PF01071.14 EIW67578.1 - 2e-77 259.1 0.0 2.8e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EIW67578.1 - 7.6e-31 106.5 0.0 1.8e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EIW67578.1 - 4.9e-28 97.1 0.0 1.3e-27 95.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS_C PF02769.17 EIW67578.1 - 5.6e-26 91.3 0.0 3e-25 89.0 0.0 2.1 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EIW67578.1 - 8.5e-17 61.1 1.1 2.6e-16 59.6 0.3 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EIW67578.1 - 2.1e-11 43.8 0.0 4.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIW67578.1 - 1.6e-06 27.1 0.0 3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EIW67578.1 - 0.0042 16.4 0.0 0.0079 15.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EIW67578.1 - 0.061 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Mito_carr PF00153.22 EIW67579.1 - 3.9e-47 157.8 8.3 1.6e-18 66.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3482 PF11981.3 EIW67579.1 - 1.6 7.8 3.6 1 8.5 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Opy2 PF09463.5 EIW67580.1 - 6.7e-07 29.2 16.6 1.1e-06 28.6 11.5 1.3 1 0 0 1 1 1 1 Opy2 protein HAMP PF00672.20 EIW67580.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 HAMP domain PGM_PMM_I PF02878.11 EIW67581.1 - 3.9e-40 136.5 0.1 5.7e-40 135.9 0.1 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EIW67581.1 - 1.1e-25 89.9 0.0 2.1e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EIW67581.1 - 8.9e-15 54.8 0.0 2.2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EIW67581.1 - 2.1e-09 37.2 0.0 5.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain WD40 PF00400.27 EIW67582.1 - 3.9e-18 64.5 3.8 2.5e-06 27.1 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EIW67582.1 - 0.022 13.0 0.0 0.038 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.7 EIW67582.1 - 0.022 14.3 0.1 0.42 10.3 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cupin_2 PF07883.6 EIW67583.1 - 7e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EIW67583.1 - 0.031 13.9 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain ACT_7 PF13840.1 EIW67584.1 - 5.8e-17 60.9 0.0 4e-09 35.8 0.0 2.7 2 0 0 2 2 2 2 ACT domain DASH_Spc19 PF08287.6 EIW67585.1 - 1.2e-19 70.4 1.7 1.8e-19 69.8 1.2 1.3 1 0 0 1 1 1 1 Spc19 DcpS_C PF11969.3 EIW67585.1 - 0.0088 16.2 0.1 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CSTF_C PF14304.1 EIW67585.1 - 0.061 12.6 1.1 0.14 11.4 0.7 1.6 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Ecl1 PF12855.2 EIW67586.1 - 0.00046 19.4 4.4 0.00086 18.5 3.1 1.4 1 0 0 1 1 1 1 Life-span regulatory factor GCV_H PF01597.14 EIW67587.1 - 1.3e-43 147.5 0.0 1.5e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EIW67587.1 - 5.7e-05 22.6 0.1 0.00011 21.8 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 EIW67587.1 - 0.0093 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain SNARE_assoc PF09335.6 EIW67590.1 - 1.8e-16 60.4 9.1 1.8e-16 60.4 6.3 2.4 2 0 0 2 2 2 1 SNARE associated Golgi protein DnaJ PF00226.26 EIW67591.1 - 0.00065 19.3 0.1 0.67 9.7 0.1 3.2 2 1 0 2 2 2 2 DnaJ domain Ppx-GppA PF02541.11 EIW67591.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RTX_C PF08339.5 EIW67591.1 - 0.023 14.4 0.1 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 RTX C-terminal domain DUF1542 PF07564.6 EIW67591.1 - 3.6 7.6 6.7 11 6.0 0.0 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) GCS PF03074.11 EIW67592.1 - 5e-161 535.8 0.5 2.8e-129 431.4 0.5 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase GCS2 PF04107.8 EIW67592.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) TBX PF12598.3 EIW67593.1 - 0.031 14.6 1.6 0.031 14.6 1.1 3.1 4 0 0 4 4 4 0 T-box transcription factor DUF500 PF04366.7 EIW67594.1 - 5.7e-43 145.3 0.0 9.2e-43 144.6 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Ric8 PF10165.4 EIW67595.1 - 1.1e-81 274.9 0.0 2.3e-81 273.9 0.0 1.4 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn FYDLN_acid PF09538.5 EIW67595.1 - 2.6 8.6 10.8 0.35 11.4 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) E1-E2_ATPase PF00122.15 EIW67596.1 - 9.4e-58 194.9 0.0 9.4e-58 194.9 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIW67596.1 - 1.1e-21 78.3 0.0 3.3e-21 76.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIW67596.1 - 2.4e-13 49.3 0.1 5.9e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIW67596.1 - 3.2e-13 50.2 0.2 8.3e-13 48.9 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIW67596.1 - 0.00011 21.9 0.0 0.00068 19.2 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Amidohydro_1 PF01979.15 EIW67597.1 - 4e-20 72.7 0.0 5.1e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family A_deaminase PF00962.17 EIW67597.1 - 0.00036 19.5 0.0 0.0014 17.6 0.0 1.7 2 0 0 2 2 2 1 Adenosine/AMP deaminase Aminotran_4 PF01063.14 EIW67598.1 - 3.8e-22 78.8 0.0 5.3e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV PTR2 PF00854.16 EIW67600.1 - 1e-25 90.3 8.4 2.2e-13 49.7 2.1 2.3 1 1 1 2 2 2 2 POT family Fungal_trans PF04082.13 EIW67603.1 - 2.7e-10 39.5 0.1 4.1e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW67603.1 - 6.7e-06 25.9 13.1 1.3e-05 25.0 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3337 PF11816.3 EIW67604.1 - 2.2e-48 165.3 1.2 8.5e-47 160.1 1.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 EIW67604.1 - 6.3e-22 76.5 21.8 6.2e-05 22.7 0.0 7.4 6 1 0 6 6 6 6 WD domain, G-beta repeat Pkinase PF00069.20 EIW67606.1 - 8.4e-67 225.0 0.0 1.1e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67606.1 - 2.8e-29 101.9 0.0 3.9e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIW67606.1 - 3.8e-20 72.1 0.1 1.1e-19 70.6 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.25 EIW67606.1 - 1.5e-08 34.3 0.0 0.00011 21.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.1 EIW67606.1 - 2.4e-08 33.2 0.0 8.5e-08 31.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIW67606.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EIW67606.1 - 0.035 13.1 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Flg_new PF09479.5 EIW67606.1 - 0.072 13.1 1.3 0.17 11.9 0.9 1.6 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) WD40 PF00400.27 EIW67607.1 - 4.8e-11 42.0 0.9 0.00022 20.9 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Cation_efflux PF01545.16 EIW67609.1 - 2.5e-31 108.8 8.2 3.1e-31 108.4 5.7 1.1 1 0 0 1 1 1 1 Cation efflux family PDCD2_C PF04194.8 EIW67610.1 - 6.7e-23 81.0 2.0 1.6e-14 53.8 0.0 2.9 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain DUF605 PF04652.11 EIW67610.1 - 0.3 10.4 19.9 0.6 9.4 13.8 1.4 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_17 PF00332.13 EIW67611.1 - 6.8e-08 31.9 4.7 2.5e-06 26.7 3.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Sugar_tr PF00083.19 EIW67612.1 - 1.3e-65 221.7 16.6 1.9e-65 221.2 11.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW67612.1 - 9.8e-30 103.4 19.8 9.8e-30 103.4 13.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EIW67612.1 - 1.2e-05 23.7 0.6 1.2e-05 23.7 0.4 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector DUF791 PF05631.9 EIW67612.1 - 0.0017 17.1 0.1 0.004 15.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 EIW67612.1 - 0.013 15.2 3.7 1.2 8.9 0.2 3.1 2 0 0 2 2 2 0 MFS_1 like family Claudin_2 PF13903.1 EIW67612.1 - 1 9.0 11.4 4.8 6.8 0.0 3.0 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Myb_DNA-binding PF00249.26 EIW67613.1 - 1.5e-08 34.5 7.3 2e-05 24.5 0.1 4.1 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW67613.1 - 2.5e-08 33.8 3.6 5.6e-08 32.7 0.4 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EIW67613.1 - 0.48 10.6 7.7 0.5 10.5 0.1 3.7 4 0 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SNF2_N PF00176.18 EIW67614.1 - 0.001 17.9 0.0 0.021 13.6 0.0 2.7 2 1 0 2 2 2 1 SNF2 family N-terminal domain D123 PF07065.9 EIW67615.1 - 1.5e-69 234.3 0.0 1.8e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 D123 HSP9_HSP12 PF04119.7 EIW67616.1 - 7.6e-09 35.5 6.7 0.00034 20.6 0.2 3.3 3 0 0 3 3 3 3 Heat shock protein 9/12 Pkinase PF00069.20 EIW67617.1 - 6.3e-40 136.9 0.0 1.6e-39 135.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67617.1 - 2.4e-19 69.4 0.0 1.1e-18 67.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW67617.1 - 2.2e-05 23.5 0.0 3.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW67617.1 - 0.0075 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Aldo_ket_red PF00248.16 EIW67618.1 - 1.3e-60 204.6 0.0 1.6e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_16 PF10294.4 EIW67620.1 - 7.8e-10 38.4 0.0 0.00022 20.7 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EIW67620.1 - 5e-05 23.8 0.0 9.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ThiF PF00899.16 EIW67621.1 - 2.8e-12 46.6 0.0 4.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family ATP_bind_4 PF01902.12 EIW67621.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 ATP-binding region Med31 PF05669.7 EIW67622.1 - 3.4e-33 113.4 1.3 3.9e-33 113.2 0.9 1.0 1 0 0 1 1 1 1 SOH1 NLE PF08154.7 EIW67623.1 - 6.6e-17 61.2 0.0 1.2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.27 EIW67623.1 - 2.1e-16 59.0 14.5 2.8e-06 26.9 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3312 PF11768.3 EIW67623.1 - 0.18 10.0 0.0 0.63 8.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) RRM_1 PF00076.17 EIW67624.1 - 2.4e-19 68.7 0.0 1.1e-11 44.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW67624.1 - 9.1e-14 51.2 0.0 9.6e-07 28.7 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW67624.1 - 2.4e-13 49.7 0.0 2.4e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIW67624.1 - 0.016 14.9 0.0 0.28 10.9 0.0 2.6 2 1 0 2 2 2 0 Limkain b1 DUF45 PF01863.12 EIW67624.1 - 0.059 13.1 0.5 0.099 12.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 VWA_2 PF13519.1 EIW67625.1 - 8.7e-13 48.7 0.0 1.3e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EIW67625.1 - 6.1e-06 26.0 0.0 9.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_beta PF00362.13 EIW67625.1 - 0.031 13.1 0.0 0.095 11.5 0.0 1.7 2 0 0 2 2 2 0 Integrin, beta chain Retinal PF15449.1 EIW67625.1 - 0.22 9.1 7.2 0.3 8.7 5.0 1.1 1 0 0 1 1 1 0 Retinal protein CAP_GLY PF01302.20 EIW67626.1 - 7.8e-21 73.5 0.7 1.4e-20 72.7 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain DMPK_coil PF08826.5 EIW67626.1 - 0.0034 17.2 5.2 0.0034 17.2 3.6 7.2 7 1 1 8 8 8 2 DMPK coiled coil domain like IncA PF04156.9 EIW67626.1 - 0.0083 15.7 83.8 0.023 14.2 7.2 5.0 2 1 2 4 4 4 3 IncA protein zf-CCHC_4 PF14392.1 EIW67626.1 - 0.31 10.7 0.7 0.61 9.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle CCDC92 PF14916.1 EIW67626.1 - 1.6 8.3 15.3 0.88 9.2 0.4 3.9 5 0 0 5 5 5 0 Coiled-coil domain of unknown function Reo_sigmaC PF04582.7 EIW67626.1 - 2.7 7.0 23.6 0.21 10.7 0.5 4.1 2 2 3 5 5 5 0 Reovirus sigma C capsid protein V-SNARE_C PF12352.3 EIW67627.1 - 0.076 13.1 0.1 0.34 11.0 0.0 2.1 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF2587 PF10759.4 EIW67629.1 - 0.033 13.5 0.1 0.11 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) BUD22 PF09073.5 EIW67629.1 - 0.42 9.6 9.7 0.84 8.6 6.7 1.4 1 0 0 1 1 1 0 BUD22 MIP-T3 PF10243.4 EIW67629.1 - 2.4 6.5 14.4 0.078 11.4 5.1 2.0 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 MOZ_SAS PF01853.13 EIW67632.1 - 1.1e-51 174.7 0.5 1.8e-50 170.8 0.2 2.1 1 1 1 2 2 2 1 MOZ/SAS family zf-C2H2_jaz PF12171.3 EIW67632.1 - 0.025 14.7 0.5 0.025 14.7 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EIW67632.1 - 0.66 10.3 0.1 0.66 10.3 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW67632.1 - 4.3 7.8 9.2 0.087 13.1 1.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW67632.1 - 4.5 7.8 7.2 0.73 10.2 1.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF159 PF02586.9 EIW67633.1 - 2.5e-45 154.5 0.0 3.5e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 RR_TM4-6 PF06459.7 EIW67633.1 - 3.6 7.4 9.3 5.2 6.8 6.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CoA_binding_2 PF13380.1 EIW67634.1 - 4.4e-15 55.8 0.0 5.1e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Polysacc_deac_1 PF01522.16 EIW67636.1 - 2.8e-26 91.5 0.0 4.6e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EIW67636.1 - 0.042 12.7 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 PseudoU_synth_1 PF01416.15 EIW67637.1 - 2.4e-20 72.9 0.0 3.5e-09 37.0 0.0 3.2 3 0 0 3 3 3 2 tRNA pseudouridine synthase ALS_ss_C PF10369.4 EIW67638.1 - 4.9e-19 67.8 0.0 2.7e-17 62.2 0.0 2.5 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EIW67638.1 - 2e-11 43.1 0.0 3.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EIW67638.1 - 2.5e-08 33.5 0.0 4.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain Mito_carr PF00153.22 EIW67639.1 - 9.8e-71 233.5 4.9 1.3e-22 79.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EIW67639.1 - 0.26 11.3 4.4 5.3 7.0 0.0 3.1 1 1 2 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family TPR_11 PF13414.1 EIW67640.1 - 5.3e-20 70.8 2.2 3e-08 33.2 0.0 3.2 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EIW67640.1 - 1.6e-16 59.1 2.3 2.1e-07 30.2 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW67640.1 - 2.1e-16 58.4 1.0 1.2e-06 27.9 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW67640.1 - 2.9e-14 53.2 0.0 1.2e-06 29.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW67640.1 - 7e-12 45.5 0.1 9.5e-07 29.0 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW67640.1 - 2.2e-11 43.5 2.0 0.0059 16.5 0.0 3.4 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIW67640.1 - 4.8e-10 38.8 1.0 0.00024 21.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW67640.1 - 1.6e-09 37.5 0.1 0.0033 17.9 0.0 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW67640.1 - 1.7e-08 33.6 0.7 0.0016 18.0 0.0 4.4 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW67640.1 - 2e-06 27.1 3.2 0.7 9.8 0.1 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIW67640.1 - 2.8e-05 24.2 0.7 0.57 10.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIW67640.1 - 2.8e-05 23.8 0.0 0.6 10.0 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW67640.1 - 0.00042 20.4 0.0 0.0017 18.4 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EIW67640.1 - 0.0076 16.1 1.2 2.5 8.1 0.3 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_5 PF12688.2 EIW67640.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_21 PF09976.4 EIW67640.1 - 0.024 14.5 0.5 4.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EIW67640.1 - 0.024 14.4 1.6 6.7 6.6 0.1 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 EIW67640.1 - 0.026 14.6 1.4 0.079 13.0 0.1 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 EIW67640.1 - 0.051 12.6 0.3 0.079 12.0 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Acyl-CoA_dh_1 PF00441.19 EIW67642.1 - 1.3e-46 158.4 1.4 1.9e-46 157.8 1.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIW67642.1 - 6.2e-27 94.4 0.4 1.6e-26 93.1 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIW67642.1 - 1.5e-21 77.0 0.4 2.7e-21 76.1 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIW67642.1 - 6.1e-19 67.2 0.0 1.2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Rep_fac_C PF08542.6 EIW67644.1 - 3.3e-17 62.2 0.0 8.8e-17 60.8 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EIW67644.1 - 1.5e-16 60.7 0.0 3.2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EIW67644.1 - 4.1e-14 52.5 0.0 8.1e-10 38.5 0.0 2.8 2 1 1 3 3 3 2 DNA polymerase III, delta subunit AAA_14 PF13173.1 EIW67644.1 - 1.3e-08 34.7 0.0 6.7e-08 32.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.10 EIW67644.1 - 4.9e-08 32.1 0.0 1.2e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 EIW67644.1 - 7.2e-07 28.8 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 EIW67644.1 - 7.3e-07 28.4 0.0 1.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIW67644.1 - 2.8e-06 27.5 0.1 0.00044 20.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EIW67644.1 - 3.2e-06 26.2 0.0 4.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EIW67644.1 - 3.4e-06 26.6 0.0 8.1e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIW67644.1 - 1.1e-05 25.5 0.0 8.2e-05 22.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EIW67644.1 - 1.1e-05 25.1 0.1 6.1e-05 22.7 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EIW67644.1 - 3.3e-05 23.5 0.1 0.00058 19.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIW67644.1 - 0.00024 20.7 0.1 0.0013 18.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIW67644.1 - 0.0013 18.2 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EIW67644.1 - 0.0022 17.4 0.2 0.03 13.8 0.1 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_17 PF13207.1 EIW67644.1 - 0.0034 18.1 0.0 0.0066 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIW67644.1 - 0.0042 16.5 0.1 0.012 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EIW67644.1 - 0.0076 15.8 0.3 0.018 14.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EIW67644.1 - 0.0078 15.3 0.0 0.041 13.0 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EIW67644.1 - 0.0084 15.9 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EIW67644.1 - 0.0088 16.3 0.0 0.024 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIW67644.1 - 0.0097 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 EIW67644.1 - 0.018 14.4 0.1 2.1 7.6 0.0 2.5 1 1 1 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EIW67644.1 - 0.019 14.3 0.1 0.062 12.7 0.1 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein SNF2_N PF00176.18 EIW67644.1 - 0.021 13.5 0.1 0.36 9.5 0.0 2.2 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_28 PF13521.1 EIW67644.1 - 0.024 14.5 0.0 0.042 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EIW67644.1 - 0.029 13.8 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 EIW67644.1 - 0.041 12.6 0.0 0.16 10.6 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EIW67644.1 - 0.069 13.1 0.0 0.25 11.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EIW67644.1 - 0.08 13.1 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 EIW67644.1 - 0.093 12.1 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EIW67644.1 - 0.1 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Kinesin PF00225.18 EIW67645.1 - 2.4e-97 325.6 0.0 3.6e-97 325.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Tropomyosin PF00261.15 EIW67645.1 - 0.002 17.2 13.1 0.002 17.2 9.1 2.6 2 1 0 2 2 2 1 Tropomyosin Apt1 PF10351.4 EIW67645.1 - 0.036 12.9 8.3 0.74 8.6 0.8 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Lebercilin PF15619.1 EIW67645.1 - 0.31 10.4 22.5 0.046 13.1 2.5 3.3 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Cep57_MT_bd PF06657.8 EIW67645.1 - 1.2 9.0 10.5 0.13 12.2 0.7 3.4 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Sec2p PF06428.6 EIW67645.1 - 1.6 8.6 14.4 0.38 10.6 1.0 3.7 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p DUF1515 PF07439.6 EIW67645.1 - 3.6 7.4 5.5 4.6 7.0 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) FemAB PF02388.11 EIW67645.1 - 8 5.0 7.2 1.3 7.6 0.5 2.1 2 0 0 2 2 2 0 FemAB family Cmc1 PF08583.5 EIW67646.1 - 0.00011 21.9 7.0 0.061 13.1 0.2 3.1 1 1 1 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 EIW67646.1 - 0.0031 17.4 5.5 0.11 12.4 0.3 2.3 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EIW67646.1 - 0.0045 16.7 3.1 1.3 8.9 0.1 2.7 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0203) CHCH PF06747.8 EIW67646.1 - 0.0051 16.7 13.1 0.11 12.4 1.1 3.8 4 1 1 5 5 5 3 CHCH domain YbfN PF13982.1 EIW67646.1 - 0.015 15.4 2.3 0.3 11.2 0.2 2.5 2 1 1 3 3 3 0 YbfN-like lipoprotein Apolipoprotein PF01442.13 EIW67646.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Pet191_N PF10203.4 EIW67646.1 - 0.028 14.4 6.6 0.55 10.3 0.8 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EIW67646.1 - 0.033 14.2 3.8 0.92 9.5 0.0 2.8 3 0 0 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.6 EIW67646.1 - 0.038 14.1 5.2 0.18 11.9 0.6 2.3 1 1 0 2 2 2 0 GCK domain COX6B PF02297.12 EIW67646.1 - 0.31 11.0 7.0 0.19 11.8 0.6 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DPBB_1 PF03330.13 EIW67649.1 - 0.00013 21.8 0.2 0.0024 17.8 0.0 2.6 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW67649.1 - 0.013 15.1 0.0 0.039 13.6 0.0 1.7 1 1 1 2 2 2 0 Barwin family DPBB_1 PF03330.13 EIW67650.1 - 1e-05 25.4 0.1 2.1e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW67650.1 - 2.7e-05 23.8 0.1 3.4e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Barwin family Barwin PF00967.12 EIW67651.1 - 6.5e-06 25.8 0.0 8.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 EIW67651.1 - 0.014 15.3 0.0 0.03 14.3 0.0 1.6 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW67652.1 - 7.3e-07 28.8 0.1 8.8e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 EIW67652.1 - 6.9e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel YadA_stalk PF05662.9 EIW67652.1 - 0.1 12.4 1.1 0.2 11.5 0.8 1.5 1 0 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin DPBB_1 PF03330.13 EIW67653.1 - 2e-05 24.5 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW67653.1 - 3.1e-05 23.6 0.1 4.3e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Barwin family Barwin PF00967.12 EIW67654.1 - 0.019 14.6 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Barwin family Ogr_Delta PF04606.7 EIW67654.1 - 0.2 11.3 1.1 0.3 10.7 0.2 1.7 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DUF3722 PF12519.3 EIW67655.1 - 3.8e-84 281.9 0.0 1.4e-83 280.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EIW67655.1 - 0.015 14.5 0.0 0.95 8.6 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic porin GPI-anchored PF10342.4 EIW67657.1 - 2.1e-08 34.5 0.9 2.1e-08 34.5 0.6 2.1 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF680 PF05079.7 EIW67657.1 - 7.7 7.0 10.6 0.44 11.0 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF680) DUF2407_C PF13373.1 EIW67658.1 - 3.1e-14 53.0 1.3 8.4e-13 48.4 0.9 2.4 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EIW67658.1 - 6.6e-08 32.6 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EIW67658.1 - 7.6e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2955 PF11168.3 EIW67658.1 - 0.29 10.7 1.4 0.42 10.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) PP2C PF00481.16 EIW67659.1 - 2e-37 128.9 0.0 1.8e-36 125.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIW67659.1 - 2.4e-05 23.8 0.0 4.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SUR7 PF06687.7 EIW67660.1 - 3.1e-25 88.9 0.8 3.1e-25 88.9 0.6 1.5 1 1 1 2 2 2 2 SUR7/PalI family Fig1 PF12351.3 EIW67660.1 - 0.0023 17.8 1.7 0.0023 17.8 1.2 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 DUF2207 PF09972.4 EIW67660.1 - 0.032 12.8 3.0 0.067 11.7 2.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3128 PF11326.3 EIW67660.1 - 0.038 14.1 0.6 0.066 13.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Tetraspannin PF00335.15 EIW67660.1 - 7.3 5.7 12.9 0.31 10.2 0.9 2.6 3 0 0 3 3 3 0 Tetraspanin family Na_H_Exchanger PF00999.16 EIW67661.1 - 2.8e-71 240.0 35.2 3.4e-71 239.8 24.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1772 PF08592.6 EIW67661.1 - 1.5 8.5 0.0 1.5 8.5 0.0 3.5 4 2 0 4 4 4 0 Domain of unknown function (DUF1772) Alpha_kinase PF02816.13 EIW67663.1 - 8.2e-12 45.1 0.5 2e-11 43.8 0.4 1.7 1 1 0 1 1 1 1 Alpha-kinase family RepA_N PF06970.6 EIW67664.1 - 0.13 12.0 0.1 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus TFIID_20kDa PF03847.8 EIW67665.1 - 3.2e-10 40.1 1.4 6.8e-10 39.0 1.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A LSM PF01423.17 EIW67666.1 - 1.5e-15 56.5 0.1 1.6e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIW67666.1 - 0.0016 18.3 0.1 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain HLH PF00010.21 EIW67667.1 - 1.5e-08 34.2 0.1 4.3e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain IncA PF04156.9 EIW67667.1 - 0.0006 19.4 4.1 0.0011 18.6 2.9 1.4 1 0 0 1 1 1 1 IncA protein PhdYeFM_antitox PF02604.14 EIW67667.1 - 0.038 13.5 0.2 0.1 12.1 0.1 1.8 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system DMPK_coil PF08826.5 EIW67667.1 - 0.21 11.4 5.2 0.73 9.7 3.6 2.0 1 1 0 1 1 1 0 DMPK coiled coil domain like ADIP PF11559.3 EIW67667.1 - 0.22 11.4 4.7 0.43 10.4 3.2 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fungal_trans PF04082.13 EIW67668.1 - 2.1e-28 98.8 0.0 3.1e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW67668.1 - 1.3e-08 34.6 10.7 2.6e-08 33.6 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 EIW67668.1 - 0.001 18.4 0.3 0.001 18.4 0.2 2.5 2 0 0 2 2 2 1 Mitochondrial fission regulator RPA_C PF08784.6 EIW67669.1 - 3.7e-14 52.9 1.0 1.2e-13 51.3 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EIW67669.1 - 1e-06 28.5 0.1 1.6e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TFIIIC_sub6 PF10419.4 EIW67670.1 - 2.2e-06 27.0 1.0 4.8e-06 25.9 0.7 1.6 1 0 0 1 1 1 1 TFIIIC subunit WHIM2 PF15613.1 EIW67671.1 - 0.008 16.0 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 PP-binding PF00550.20 EIW67672.1 - 6.7e-13 48.6 0.6 7.8e-13 48.4 0.4 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EIW67672.1 - 0.00043 20.2 0.9 0.00063 19.7 0.6 1.3 1 1 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EIW67672.1 - 0.022 14.8 0.2 0.028 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L17 PF01196.14 EIW67673.1 - 2e-32 111.5 0.0 4.5e-32 110.4 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L17 DUF2036 PF09724.4 EIW67674.1 - 1.4e-61 208.4 0.0 1.8e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Vps36_ESCRT-II PF11605.3 EIW67675.1 - 0.03 14.1 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Vps5 PF09325.5 EIW67676.1 - 8e-64 215.1 5.4 1e-63 214.7 3.8 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EIW67676.1 - 1.7e-22 79.3 0.0 4.4e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 EIW67676.1 - 0.00071 18.9 0.7 0.0062 15.8 0.4 2.1 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Cortex-I_coil PF09304.5 EIW67676.1 - 0.011 15.8 5.5 0.22 11.5 1.6 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF4134 PF13572.1 EIW67676.1 - 0.029 14.4 0.0 0.1 12.7 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4134) FliE PF02049.13 EIW67676.1 - 1 9.4 6.9 19 5.3 0.7 3.1 2 2 1 3 3 3 0 Flagellar hook-basal body complex protein FliE Glyco_hydro_16 PF00722.16 EIW67677.1 - 4.6e-13 48.8 0.7 4.6e-13 48.8 0.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Bap31 PF05529.7 EIW67678.1 - 9.5e-47 158.9 2.9 1.5e-46 158.2 2.0 1.2 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Arf PF00025.16 EIW67680.1 - 1.9e-71 238.9 0.0 2.2e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIW67680.1 - 1.1e-14 54.0 0.0 1.4e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIW67680.1 - 6.6e-11 41.5 0.2 4.1e-07 29.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EIW67680.1 - 7.7e-11 41.6 0.0 8.3e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EIW67680.1 - 2.5e-10 39.8 0.0 3.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIW67680.1 - 1.7e-08 35.0 0.0 2.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW67680.1 - 6.8e-05 22.7 0.0 9.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EIW67680.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase FeoB_N PF02421.13 EIW67680.1 - 0.096 11.9 0.3 0.31 10.3 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF2373 PF10180.4 EIW67681.1 - 1.3e-14 53.4 0.0 2.8e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) UMP1 PF05348.6 EIW67682.1 - 5.9e-20 71.5 0.7 4.5e-19 68.6 0.5 1.9 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 Snapin_Pallidin PF14712.1 EIW67682.1 - 0.053 13.8 0.0 0.074 13.3 0.0 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Pkinase PF00069.20 EIW67683.1 - 1.4e-38 132.5 0.0 1.7e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67683.1 - 1.4e-14 53.8 0.0 1.9e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW67683.1 - 4.6e-06 26.5 2.2 0.0022 17.7 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIW67683.1 - 0.02 13.7 0.1 0.029 13.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CitT PF12431.3 EIW67683.1 - 0.12 12.4 0.2 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator Metallophos PF00149.23 EIW67684.1 - 0.00013 21.4 0.8 0.00026 20.4 0.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW67684.1 - 0.016 15.0 0.1 0.06 13.1 0.1 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Helicase_C PF00271.26 EIW67685.1 - 8.3e-16 57.6 0.0 2.3e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIW67685.1 - 2.3e-13 49.6 0.0 4.1e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 MobB PF03205.9 EIW67685.1 - 0.1 12.3 0.2 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B tRNA-synt_1g PF09334.6 EIW67686.1 - 1.3e-126 422.4 0.0 1.7e-126 422.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EIW67686.1 - 0.0019 16.3 0.0 0.0055 14.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIW67686.1 - 0.0023 17.6 0.2 0.01 15.6 0.0 2.2 2 1 1 3 3 3 1 Anticodon-binding domain of tRNA DUF2201_N PF13203.1 EIW67686.1 - 0.49 9.5 3.8 0.78 8.8 2.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain WHEP-TRS PF00458.15 EIW67686.1 - 1.9 8.1 16.4 0.017 14.7 5.8 1.8 2 0 0 2 2 2 0 WHEP-TRS domain Clp1 PF06807.9 EIW67687.1 - 9.4e-08 32.0 0.0 1.5e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 PPR_3 PF13812.1 EIW67688.1 - 1.7e-07 30.9 0.0 0.047 13.9 0.0 4.2 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EIW67688.1 - 4.4e-06 26.5 0.0 0.094 12.7 0.0 3.1 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.15 EIW67688.1 - 1.1e-05 25.0 0.0 0.1 12.6 0.0 4.2 4 0 0 4 4 4 2 PPR repeat TPR_14 PF13428.1 EIW67688.1 - 0.063 13.9 0.0 1.9 9.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.1 EIW67689.1 - 1.5e-07 31.0 2.1 0.014 15.1 0.0 3.7 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EIW67689.1 - 0.012 15.2 9.3 0.17 11.5 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIW67689.1 - 0.02 14.8 5.9 7.9 6.9 0.4 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.1 EIW67689.1 - 0.96 9.7 6.7 6.3 7.1 0.2 4.5 6 0 0 6 6 6 0 Leucine Rich repeat UQ_con PF00179.21 EIW67690.1 - 4.8e-36 123.2 0.0 6.8e-36 122.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_S21e PF01249.13 EIW67693.1 - 1.6e-35 120.8 0.2 1.8e-35 120.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FliC_SP PF12613.3 EIW67693.1 - 0.72 10.1 2.9 1.4 9.1 1.9 1.6 1 1 1 2 2 2 0 Flagellin structural protein Cupin_8 PF13621.1 EIW67694.1 - 1e-45 156.1 0.0 1.5e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EIW67694.1 - 0.0062 16.7 0.1 0.015 15.5 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EIW67694.1 - 0.019 14.4 0.1 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.7 EIW67694.1 - 0.034 13.3 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein cNMP_binding PF00027.24 EIW67695.1 - 1.2e-32 111.5 0.0 9.7e-13 47.7 0.0 4.6 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EIW67695.1 - 8e-19 68.3 5.0 7.3e-15 55.4 4.5 3.4 3 1 0 3 3 3 1 Patatin-like phospholipase RRN3 PF05327.6 EIW67696.1 - 7.7e-152 506.2 0.0 6.4e-151 503.2 0.0 2.1 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF2146 PF10220.4 EIW67696.1 - 4.4 5.1 5.8 8.2 4.2 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2146) Ribonuclease_3 PF00636.21 EIW67697.1 - 9.9e-10 38.8 0.0 3.1e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIW67697.1 - 7.1e-09 35.7 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Bestrophin PF01062.16 EIW67698.1 - 1.5e-42 145.5 0.5 6e-21 74.6 1.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Cys_Met_Meta_PP PF01053.15 EIW67699.1 - 1.7e-92 309.7 0.0 3.8e-62 209.8 0.0 2.9 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Ribosomal_L22 PF00237.14 EIW67700.1 - 1.1e-28 99.2 0.1 1.5e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Mog1 PF04603.7 EIW67701.1 - 1.6e-22 79.9 0.0 2.8e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Ran-interacting Mog1 protein NuA4 PF09340.5 EIW67702.1 - 1.6e-07 30.8 0.0 1.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Enkurin PF13864.1 EIW67702.1 - 0.012 15.7 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Calmodulin-binding UAA PF08449.6 EIW67703.1 - 8.2e-09 34.8 9.3 1.3e-08 34.1 6.4 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EIW67703.1 - 1.2e-07 31.1 0.3 2.2e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EIW67703.1 - 0.00046 20.2 4.6 0.00046 20.2 3.2 3.2 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 EIW67703.1 - 0.0025 17.4 19.3 0.096 12.3 0.5 2.4 3 0 0 3 3 3 2 Triose-phosphate Transporter family RRM_6 PF14259.1 EIW67704.1 - 2.2e-35 120.4 0.0 5.5e-14 51.9 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW67704.1 - 1.6e-31 107.7 0.0 1e-11 44.2 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW67704.1 - 4.9e-18 64.7 0.0 2.2e-07 30.6 0.0 4.9 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EIW67704.1 - 7.9e-05 22.5 0.1 0.00052 19.8 0.0 2.4 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) TspO_MBR PF03073.10 EIW67706.1 - 3.9e-42 143.2 9.3 4.9e-42 142.9 6.5 1.0 1 0 0 1 1 1 1 TspO/MBR family RIO1 PF01163.17 EIW67707.1 - 1.2e-65 220.4 1.8 2.2e-65 219.5 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 EIW67707.1 - 0.0001 21.5 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIW67707.1 - 0.00041 20.1 0.2 0.0013 18.5 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW67707.1 - 0.051 12.6 1.1 0.59 9.1 0.8 2.1 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIW67707.1 - 0.067 12.7 0.2 0.41 10.1 0.1 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase ORMDL PF04061.9 EIW67708.1 - 1.7e-53 179.7 1.0 2.2e-53 179.4 0.7 1.1 1 0 0 1 1 1 1 ORMDL family PPR_3 PF13812.1 EIW67709.1 - 7.4e-18 63.2 2.4 0.038 14.2 0.0 6.5 6 0 0 6 6 6 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 EIW67709.1 - 4.3e-13 49.0 0.1 7.8e-05 22.5 0.0 5.2 3 1 2 5 5 5 4 PPR repeat family PPR PF01535.15 EIW67709.1 - 1.7e-09 36.9 0.4 1.9 8.6 0.0 5.7 6 0 0 6 6 6 3 PPR repeat ATP13 PF12921.2 EIW67709.1 - 0.00088 18.6 0.0 0.21 10.9 0.0 3.2 3 1 0 3 3 3 1 Mitochondrial ATPase expression DUF1956 PF09209.6 EIW67709.1 - 0.0024 17.7 0.8 0.0085 16.0 0.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1956) TPR_14 PF13428.1 EIW67709.1 - 0.03 14.9 1.1 51 4.8 0.0 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat ICAM_N PF03921.9 EIW67709.1 - 0.087 12.3 0.1 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain UPF0203 PF05254.7 EIW67710.1 - 5.4e-14 51.8 1.9 4e-13 48.9 1.3 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 EIW67710.1 - 0.075 12.9 0.6 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 EIW67710.1 - 0.44 10.5 4.6 7.1 6.7 0.2 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EIW67710.1 - 0.55 10.2 2.5 2.1 8.3 0.2 2.2 2 0 0 2 2 2 0 CHCH domain Myb_DNA-bind_4 PF13837.1 EIW67712.1 - 0.011 15.8 0.1 0.031 14.4 0.1 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.1 EIW67713.1 - 0.00012 21.7 0.0 0.00013 21.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Herpes_UL56 PF04534.7 EIW67714.1 - 0.026 14.2 1.0 0.056 13.1 0.7 1.5 1 0 0 1 1 1 0 Herpesvirus UL56 protein Cupin_8 PF13621.1 EIW67716.1 - 8.1e-25 87.7 0.0 1.1e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EIW67716.1 - 0.00088 18.6 0.0 0.0068 15.6 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.6 EIW67716.1 - 0.014 14.9 0.0 0.037 13.5 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Chitin_synth_1 PF01644.12 EIW67717.1 - 6.9e-74 247.0 0.0 1.1e-73 246.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EIW67717.1 - 2.3e-22 79.0 1.6 5.9e-20 71.1 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EIW67717.1 - 5e-21 74.1 0.1 9e-21 73.3 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EIW67717.1 - 4.1e-13 49.4 2.5 1e-12 48.2 0.4 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW67717.1 - 8.9e-08 32.2 0.0 2.2e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 CDC50 PF03381.10 EIW67719.1 - 5.4e-93 311.1 0.3 8.9e-93 310.4 0.0 1.4 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.1 EIW67719.1 - 0.18 11.9 1.3 6.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Alpha-amylase PF00128.19 EIW67720.1 - 1.8e-16 60.4 0.5 1.5e-13 50.8 0.0 2.7 2 1 1 3 3 3 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EIW67720.1 - 3.4e-06 27.1 0.0 7.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Pkinase PF00069.20 EIW67721.1 - 3.1e-72 242.8 0.0 3.6e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67721.1 - 4.5e-35 120.9 0.0 5.9e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW67721.1 - 6.8e-06 25.2 0.0 3.7e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EIW67721.1 - 0.02 14.6 0.4 0.051 13.2 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EIW67721.1 - 0.022 13.8 0.1 0.06 12.4 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIW67721.1 - 0.031 13.1 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2968 PF11180.3 EIW67722.1 - 0.05 12.9 0.4 0.064 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) SNF2_N PF00176.18 EIW67723.1 - 1.3e-44 152.2 0.0 1.9e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW67723.1 - 3.3e-14 52.4 0.0 7.9e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW67723.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW67723.1 - 0.00042 20.2 0.0 0.0024 17.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW67723.1 - 0.069 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EIW67723.1 - 0.2 11.2 2.9 0.27 10.7 0.1 2.3 2 1 1 3 3 3 0 AAA domain ALO PF04030.9 EIW67724.1 - 3.2e-80 269.4 0.4 4.6e-80 268.9 0.3 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EIW67724.1 - 9e-16 57.6 0.0 1.6e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Peptidase_M50B PF13398.1 EIW67725.1 - 2.9e-26 92.0 6.0 9.1e-18 64.3 3.3 2.0 2 0 0 2 2 2 2 Peptidase M50B-like Na_Pi_cotrans PF02690.10 EIW67725.1 - 0.022 14.4 1.7 0.04 13.6 1.2 1.3 1 0 0 1 1 1 0 Na+/Pi-cotransporter DUF543 PF04418.7 EIW67726.1 - 7.4e-27 93.1 0.1 8.3e-27 92.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Ndr PF03096.9 EIW67726.1 - 0.12 10.7 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family RRM_1 PF00076.17 EIW67728.1 - 2.2e-07 30.4 0.0 4.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW67728.1 - 0.0016 18.3 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW67728.1 - 0.013 15.3 0.0 0.094 12.5 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EIW67728.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain Dfp1_Him1_M PF08630.5 EIW67729.1 - 1.1e-24 86.6 1.3 3.9e-24 84.8 0.1 2.3 2 1 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 EIW67729.1 - 5e-19 67.7 0.0 9.3e-19 66.8 0.0 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EIW67729.1 - 2.7e-05 24.2 0.5 6.7e-05 22.9 0.1 1.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EIW67729.1 - 0.021 14.6 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain DUF3315 PF11776.3 EIW67729.1 - 0.13 11.8 0.9 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3315) HSP70 PF00012.15 EIW67730.1 - 4.4e-263 873.6 7.9 5e-263 873.5 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIW67730.1 - 8.2e-17 60.7 0.8 2e-15 56.2 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EIW67730.1 - 0.00078 18.3 1.0 0.01 14.6 0.7 2.3 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EIW67730.1 - 0.0036 16.4 4.6 1 8.3 1.9 3.2 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Ppx-GppA PF02541.11 EIW67730.1 - 0.011 14.9 0.3 0.023 13.9 0.2 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family FtsA PF14450.1 EIW67730.1 - 0.45 10.3 5.8 3.6 7.4 0.2 3.8 2 1 0 2 2 2 0 Cell division protein FtsA SPC22 PF04573.7 EIW67731.1 - 2.7e-25 88.5 0.0 2.6e-23 82.1 0.0 2.0 1 1 0 1 1 1 1 Signal peptidase subunit IncA PF04156.9 EIW67734.1 - 0.027 14.0 1.1 0.049 13.2 0.8 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EIW67734.1 - 3.3 6.6 4.4 2.3 7.1 1.8 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 OTU PF02338.14 EIW67737.1 - 9e-09 35.9 0.0 1.5e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Ins145_P3_rec PF08709.6 EIW67737.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Cas1_AcylT PF07779.7 EIW67738.1 - 1.3e-164 548.3 22.0 3.9e-164 546.7 15.2 1.6 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EIW67738.1 - 4.8e-41 141.3 0.0 7.2e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Mus7 PF09462.5 EIW67739.1 - 7.7e-20 71.2 0.0 1e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family Mus7 PF09462.5 EIW67740.1 - 9.3e-60 203.1 5.5 1.4e-59 202.5 3.8 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Sec61_beta PF03911.11 EIW67741.1 - 1.2e-16 60.1 0.6 1.6e-16 59.7 0.4 1.2 1 0 0 1 1 1 1 Sec61beta family APG9 PF04109.11 EIW67742.1 - 6.5e-164 545.2 0.0 9.3e-164 544.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 DNA_pol_E_B PF04042.11 EIW67746.1 - 0.19 10.9 0.8 0.26 10.5 0.5 1.3 1 1 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B GSHPx PF00255.14 EIW67747.1 - 2.1e-37 126.7 0.1 2.7e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EIW67747.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family SRF-TF PF00319.13 EIW67748.1 - 2.5e-22 77.8 0.1 3.2e-22 77.4 0.1 1.1 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) NMT PF01233.14 EIW67750.1 - 6.2e-83 276.2 0.0 8.6e-83 275.8 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EIW67750.1 - 8.6e-66 220.9 0.0 1.3e-65 220.3 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EIW67750.1 - 0.00054 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW67750.1 - 0.054 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW67750.1 - 0.098 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HATPase_c PF02518.21 EIW67759.1 - 3.3e-16 59.0 0.1 9.5e-16 57.4 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIW67759.1 - 1.9e-15 56.8 0.0 4.2e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EIW67759.1 - 4.4e-05 23.3 1.3 0.00016 21.5 0.9 2.1 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain TAF PF02969.12 EIW67759.1 - 0.1 12.5 0.1 11 6.0 0.0 2.7 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) NUC173 PF08161.7 EIW67760.1 - 4.3e-34 117.6 0.0 2.5e-33 115.1 0.0 2.1 2 0 0 2 2 2 1 NUC173 domain YCII PF03795.9 EIW67764.1 - 0.00037 20.6 0.0 0.00061 19.9 0.0 1.3 1 1 0 1 1 1 1 YCII-related domain Ribonuc_L-PSP PF01042.16 EIW67765.1 - 2.2e-23 82.2 0.0 2.7e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Epimerase PF01370.16 EIW67766.1 - 1.8e-09 37.4 0.1 1.1e-08 34.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW67766.1 - 0.011 14.5 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family P5-ATPase PF12409.3 EIW67769.1 - 0.083 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter Xpo1 PF08389.7 EIW67770.1 - 9.2e-20 71.0 0.0 3.9e-17 62.5 0.0 3.8 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EIW67770.1 - 2.2e-06 27.4 0.2 1.4e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EIW67770.1 - 1.8e-05 24.8 4.6 0.17 12.1 0.0 4.7 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EIW67770.1 - 0.00072 19.9 4.4 1.9 9.0 0.0 5.0 4 1 0 4 4 4 2 HEAT-like repeat NUC173 PF08161.7 EIW67770.1 - 0.012 14.9 0.1 0.088 12.1 0.0 2.4 2 0 0 2 2 2 0 NUC173 domain HEAT PF02985.17 EIW67770.1 - 0.029 14.4 0.8 15 5.9 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat LSM PF01423.17 EIW67771.1 - 4.9e-14 51.6 0.0 7e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain GHMP_kinases_N PF00288.21 EIW67773.1 - 1.5e-09 37.7 0.1 3.5e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIW67773.1 - 5.2e-05 23.3 0.0 0.00016 21.8 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Herpes_glycop_H PF02489.11 EIW67773.1 - 0.11 10.4 1.1 0.17 9.8 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein H zf-H2C2_2 PF13465.1 EIW67774.1 - 6.5e-13 48.2 11.3 1.9e-07 31.0 1.8 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIW67774.1 - 7.8e-11 41.6 10.0 4.1e-05 23.6 0.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW67774.1 - 3.9e-07 29.9 9.9 0.00092 19.3 0.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW67774.1 - 0.0054 16.8 2.4 0.31 11.2 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIW67774.1 - 0.14 12.1 1.4 15 5.6 0.4 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-CHCC PF10276.4 EIW67774.1 - 0.16 11.8 1.9 11 5.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain SAC3_GANP PF03399.11 EIW67776.1 - 2.5e-62 210.0 0.4 3.6e-62 209.5 0.3 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EIW67776.1 - 5.6e-06 26.1 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TMEM154 PF15102.1 EIW67776.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF3883 PF13020.1 EIW67778.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) zf-CHY PF05495.7 EIW67781.1 - 4.8e-15 55.4 15.1 6.2e-15 55.1 10.5 1.1 1 0 0 1 1 1 1 CHY zinc finger zinc_ribbon_2 PF13240.1 EIW67781.1 - 0.003 17.0 9.8 0.024 14.0 0.4 3.3 3 0 0 3 3 3 1 zinc-ribbon domain Cys_rich_KTR PF14205.1 EIW67781.1 - 0.0088 15.4 6.1 0.81 9.1 1.9 2.4 1 1 1 2 2 2 2 Cysteine-rich KTR zf-ribbon_3 PF13248.1 EIW67781.1 - 0.017 14.3 5.6 0.41 9.9 1.5 2.5 2 1 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 EIW67781.1 - 0.022 14.4 1.7 0.022 14.4 1.2 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EIW67781.1 - 0.031 14.2 11.7 0.072 13.0 2.7 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-FPG_IleRS PF06827.9 EIW67781.1 - 0.046 13.3 1.5 0.046 13.3 1.1 2.3 2 1 1 3 3 2 0 Zinc finger found in FPG and IleRS Tmemb_55A PF09788.4 EIW67781.1 - 0.06 12.4 4.3 0.075 12.1 3.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A Zn_Tnp_IS1595 PF12760.2 EIW67781.1 - 0.16 11.7 10.9 1.9 8.3 4.5 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DRP PF06044.7 EIW67781.1 - 0.16 10.9 3.9 0.1 11.6 0.6 1.8 1 1 1 2 2 2 0 Dam-replacing family SIR2 PF02146.12 EIW67781.1 - 0.26 11.0 2.2 0.33 10.6 1.5 1.2 1 0 0 1 1 1 0 Sir2 family DZR PF12773.2 EIW67781.1 - 0.37 10.6 11.3 2.1 8.2 7.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-H2C2_2 PF13465.1 EIW67781.1 - 0.52 10.7 12.0 5.4 7.4 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Elf1 PF05129.8 EIW67781.1 - 0.8 9.4 10.8 6.8 6.4 7.6 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF3797 PF12677.2 EIW67781.1 - 1 9.0 5.8 6.8 6.3 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3797) Evr1_Alr PF04777.8 EIW67781.1 - 1 9.3 10.1 86 3.1 7.0 2.9 1 1 0 1 1 1 0 Erv1 / Alr family zf-RING_3 PF14369.1 EIW67781.1 - 1.6 8.7 11.1 0.39 10.7 1.9 2.9 2 1 1 3 3 3 0 zinc-finger C1_4 PF07975.7 EIW67781.1 - 1.8 8.6 11.8 1.4 9.0 2.0 2.7 1 1 2 3 3 3 0 TFIIH C1-like domain PhnA_Zn_Ribbon PF08274.7 EIW67781.1 - 4.6 7.0 7.5 15 5.5 0.3 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon LIM PF00412.17 EIW67781.1 - 5.4 7.1 12.9 18 5.4 7.7 2.2 1 1 1 2 2 2 0 LIM domain Ogr_Delta PF04606.7 EIW67781.1 - 9.6 5.9 8.2 18 5.0 0.1 3.1 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger DUF2587 PF10759.4 EIW67786.1 - 0.047 13.0 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW67787.1 - 0.00072 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW67787.1 - 0.35 11.1 7.5 0.09 13.0 3.0 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW67787.1 - 0.63 8.5 2.3 0.84 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) TPR_15 PF13429.1 EIW67788.1 - 0.11 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-CCHC PF00098.18 EIW67789.1 - 0.0002 21.1 1.3 0.00033 20.4 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW67789.1 - 0.039 13.6 1.1 0.12 12.0 0.7 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIW67789.1 - 0.14 11.9 1.9 0.28 10.9 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIW67789.1 - 1.1 8.8 4.6 0.48 9.9 1.3 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.3 EIW67789.1 - 3.6 7.4 8.9 0.44 10.4 0.9 2.2 1 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G EBP50_C-term PF09007.6 EIW67790.1 - 0.094 12.5 0.6 0.27 11.1 0.4 1.8 1 0 0 1 1 1 0 EBP50, C-terminal Beta_protein PF14350.1 EIW67791.1 - 0.089 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Beta protein WD40 PF00400.27 EIW67792.1 - 9.3e-19 66.5 9.9 1.6e-05 24.6 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat TruD PF01142.13 EIW67793.1 - 3.2e-64 216.9 0.0 1.6e-54 185.0 0.0 3.2 2 1 1 3 3 3 2 tRNA pseudouridine synthase D (TruD) Cyt_c_ox_IV PF12270.3 EIW67793.1 - 0.099 12.3 0.1 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV NOB1_Zn_bind PF08772.6 EIW67794.1 - 2.4e-29 100.9 1.8 4.1e-29 100.2 1.3 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS1595 PF12760.2 EIW67794.1 - 0.013 15.3 1.4 0.025 14.3 0.9 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-TFIIIC PF12660.2 EIW67794.1 - 0.1 12.4 1.0 0.2 11.5 0.7 1.4 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex AF1Q PF15017.1 EIW67794.1 - 0.19 11.6 1.9 0.45 10.4 0.1 2.4 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator zf-ribbon_3 PF13248.1 EIW67794.1 - 1.6 8.0 4.6 3.4 7.0 3.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF2433 PF10360.4 EIW67795.1 - 1.4e-25 90.0 0.2 4.3e-25 88.5 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.17 EIW67795.1 - 2.8e-14 52.5 0.1 6.6e-13 48.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW67795.1 - 1.2e-11 44.4 0.2 7.9e-11 41.7 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW67795.1 - 0.047 13.5 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_23 PF13489.1 EIW67796.1 - 6.4e-11 42.2 0.0 9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW67796.1 - 1.2e-09 38.5 0.0 2.5e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW67796.1 - 6.7e-09 35.5 0.0 3.7e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW67796.1 - 0.00023 21.5 0.0 0.00046 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW67796.1 - 0.00024 21.6 0.0 0.00046 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW67796.1 - 0.00092 19.2 0.0 0.0079 16.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW67796.1 - 0.026 14.9 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATE_C PF04377.10 EIW67796.1 - 0.063 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus Glyoxal_oxid_N PF07250.6 EIW67797.1 - 8.7e-42 142.8 0.0 5.4e-39 133.7 0.0 3.0 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIW67797.1 - 5.1e-20 71.3 0.1 1e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIW67797.1 - 8.7e-07 28.6 0.4 4.5 7.1 0.1 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Acetyltransf_3 PF13302.1 EIW67798.1 - 1.2e-12 48.1 0.2 3.3e-10 40.2 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW67798.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein AstA PF04958.7 EIW67798.1 - 0.031 12.6 0.0 0.048 12.0 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Ndufs5 PF10200.4 EIW67799.1 - 1.6e-05 24.8 0.4 2.1e-05 24.4 0.3 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.5 EIW67799.1 - 0.0049 16.6 3.4 0.0082 15.8 2.3 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EIW67799.1 - 0.013 15.4 0.8 0.024 14.6 0.6 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.3 EIW67799.1 - 0.29 11.2 1.5 0.46 10.6 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) 4F5 PF04419.9 EIW67799.1 - 0.82 10.4 4.6 1.2 9.8 3.2 1.2 1 0 0 1 1 1 0 4F5 protein family COX6B PF02297.12 EIW67799.1 - 1.1 9.2 5.6 16 5.6 3.9 2.2 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.20 EIW67800.1 - 9.9e-73 244.4 0.0 1.4e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67800.1 - 3.4e-42 144.3 0.0 5.1e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EIW67800.1 - 3e-26 91.1 0.0 2.1e-13 50.0 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EIW67800.1 - 2.2e-07 30.1 0.0 9.9e-06 24.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIW67800.1 - 0.022 13.8 0.0 0.32 10.0 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4520 PF15016.1 EIW67800.1 - 0.12 11.9 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Flagellin_N PF00669.15 EIW67801.1 - 0.0078 16.0 0.4 0.0097 15.7 0.3 1.1 1 0 0 1 1 1 1 Bacterial flagellin N-terminal helical region Pkinase PF00069.20 EIW67802.1 - 9.1e-45 152.8 0.0 2.6e-26 92.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67802.1 - 2.2e-17 63.0 0.0 3.5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Senescence PF06911.7 EIW67803.1 - 9.3e-16 58.0 7.5 1.3e-15 57.6 5.2 1.1 1 0 0 1 1 1 1 Senescence-associated protein GST_N_2 PF13409.1 EIW67804.1 - 3.2e-20 71.9 0.0 7.4e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW67804.1 - 7.7e-15 54.5 0.0 2.3e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW67804.1 - 3.2e-06 27.0 0.0 7.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW67804.1 - 5.2e-05 23.6 0.0 0.00012 22.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW67804.1 - 0.0033 17.6 0.0 0.081 13.1 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Lentivirus_VIF PF05851.6 EIW67804.1 - 0.065 11.9 0.1 0.12 10.9 0.1 1.4 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) Meth_synt_2 PF01717.13 EIW67806.1 - 1.1e-146 487.9 0.0 7e-139 462.3 0.0 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EIW67806.1 - 8.2e-109 363.6 0.0 1.7e-96 323.1 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EIW67806.1 - 0.0065 15.4 0.0 0.64 8.8 0.0 2.4 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) DUF1311 PF07007.7 EIW67806.1 - 0.074 13.1 0.1 0.29 11.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) Rad51 PF08423.6 EIW67807.1 - 1.4e-16 60.1 0.6 1.8e-09 36.9 0.1 2.6 3 0 0 3 3 3 2 Rad51 AAA_25 PF13481.1 EIW67807.1 - 7.2e-10 38.5 0.1 3.5e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EIW67807.1 - 0.00083 18.5 1.2 0.0043 16.2 0.2 2.2 2 0 0 2 2 2 1 KaiC RecA PF00154.16 EIW67807.1 - 0.0017 17.4 4.0 0.0092 15.0 0.3 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.10 EIW67807.1 - 0.024 13.5 0.1 0.061 12.1 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain HEM4 PF02602.10 EIW67808.1 - 3.5e-24 85.3 0.0 1.2e-08 34.4 0.0 3.1 3 0 0 3 3 3 3 Uroporphyrinogen-III synthase HemD Aa_trans PF01490.13 EIW67809.1 - 5e-87 292.0 11.1 6e-87 291.7 7.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sigma70_ner PF04546.8 EIW67809.1 - 0.41 10.2 1.5 0.63 9.6 1.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region FHA PF00498.21 EIW67810.1 - 2.2e-07 30.8 0.0 4.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Cu-oxidase PF00394.17 EIW67811.1 - 3.5e-32 111.4 0.0 3.3e-30 105.0 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIW67811.1 - 4.7e-30 103.7 1.6 4.7e-29 100.5 0.4 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIW67811.1 - 5.9e-20 71.1 6.7 1.1e-17 63.7 0.5 3.5 2 2 0 2 2 2 2 Multicopper oxidase TFIID_30kDa PF03540.8 EIW67811.1 - 0.098 12.5 0.0 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Prefoldin PF02996.12 EIW67812.1 - 4.9e-25 87.5 0.9 6.6e-25 87.0 0.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EIW67812.1 - 9.9e-06 25.2 5.5 0.0016 18.1 0.8 2.1 2 0 0 2 2 2 2 Prefoldin subunit Cep57_MT_bd PF06657.8 EIW67812.1 - 0.00099 19.0 2.1 0.75 9.7 0.3 2.3 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 COG2 PF06148.6 EIW67812.1 - 0.0028 17.5 3.6 0.85 9.4 0.0 2.1 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 ERM PF00769.14 EIW67812.1 - 0.0045 16.5 0.9 0.0093 15.5 0.7 1.4 1 1 0 1 1 1 1 Ezrin/radixin/moesin family Prefoldin_3 PF13758.1 EIW67812.1 - 0.0072 16.0 0.9 0.026 14.2 0.6 2.0 1 1 0 1 1 1 1 Prefoldin subunit OmpH PF03938.9 EIW67812.1 - 0.0091 15.9 7.0 0.025 14.5 0.4 2.2 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.7 EIW67812.1 - 0.017 14.9 2.1 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HR1 PF02185.11 EIW67812.1 - 0.034 13.8 1.9 0.034 13.8 1.3 2.9 2 2 0 2 2 2 0 Hr1 repeat UPF0449 PF15136.1 EIW67812.1 - 0.036 14.2 2.9 0.96 9.6 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF1409 PF07197.7 EIW67812.1 - 0.043 13.8 4.7 0.24 11.4 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) GAS PF13851.1 EIW67812.1 - 0.05 12.7 8.8 0.29 10.3 1.6 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 EIW67812.1 - 0.066 12.6 6.0 0.21 11.0 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.7 EIW67812.1 - 0.11 12.3 3.4 2.4 7.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Methyltransf_12 PF08242.7 EIW67812.1 - 0.11 13.0 0.3 6.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DASH_Dad2 PF08654.5 EIW67812.1 - 0.11 12.5 2.3 3.2 7.7 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 DUF883 PF05957.8 EIW67812.1 - 0.11 12.8 2.8 4.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4164 PF13747.1 EIW67812.1 - 0.12 12.4 0.9 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF2321 PF10083.4 EIW67812.1 - 0.13 11.7 0.3 0.96 8.9 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Fib_alpha PF08702.5 EIW67812.1 - 0.14 12.3 6.4 2.2 8.4 1.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Mod_r PF07200.8 EIW67812.1 - 0.17 11.7 7.5 0.38 10.6 0.2 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TACC PF05010.9 EIW67812.1 - 0.2 11.4 7.3 3.1 7.4 1.4 2.0 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Sec2p PF06428.6 EIW67812.1 - 0.34 10.7 6.5 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF842 PF05811.8 EIW67812.1 - 0.5 9.8 4.0 3.5 7.0 0.6 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Cortex-I_coil PF09304.5 EIW67812.1 - 0.5 10.4 10.2 3 7.9 0.5 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil ZapA PF05164.8 EIW67812.1 - 0.66 9.9 3.1 3.7 7.5 1.3 2.4 1 1 1 2 2 2 0 Cell division protein ZapA WXG100 PF06013.7 EIW67812.1 - 0.68 9.9 4.9 2.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF4200 PF13863.1 EIW67812.1 - 0.82 9.6 8.5 3.5 7.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3552 PF12072.3 EIW67812.1 - 1 8.5 10.5 3.1 6.9 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) bZIP_1 PF00170.16 EIW67812.1 - 1.4 8.9 4.9 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 bZIP transcription factor Occludin_ELL PF07303.8 EIW67812.1 - 1.5 9.5 6.3 21 5.9 1.7 2.1 2 0 0 2 2 2 0 Occludin homology domain DUF4358 PF14270.1 EIW67812.1 - 1.8 8.4 7.6 1.5 8.7 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4358) Spc7 PF08317.6 EIW67812.1 - 3 6.4 9.5 1.7 7.2 0.5 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EIW67812.1 - 8.3 4.1 6.7 44 1.7 4.6 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family NUDIX PF00293.23 EIW67813.1 - 0.00057 19.5 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TPR_11 PF13414.1 EIW67815.1 - 5.8e-58 192.4 36.9 2.1e-12 46.5 0.1 6.5 2 2 7 9 9 9 9 TPR repeat TPR_1 PF00515.23 EIW67815.1 - 4.9e-51 168.3 23.5 5.8e-08 32.0 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EIW67815.1 - 5e-45 147.8 18.9 2.5e-05 23.8 0.0 10.5 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 EIW67815.1 - 2.4e-31 105.1 20.1 0.00076 19.0 0.1 10.2 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 EIW67815.1 - 3.6e-30 103.7 12.9 4.8e-07 29.6 0.0 6.5 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.1 EIW67815.1 - 5.6e-29 100.1 9.3 1.3e-07 32.0 0.0 6.4 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 EIW67815.1 - 1.6e-27 93.3 15.8 0.00026 20.9 0.0 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIW67815.1 - 1.3e-25 87.4 9.8 0.00027 21.2 0.2 9.0 5 3 5 10 10 9 6 Tetratricopeptide repeat TPR_7 PF13176.1 EIW67815.1 - 5.5e-25 85.1 12.4 6.9e-05 22.3 0.0 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EIW67815.1 - 1.5e-21 76.5 5.6 0.00016 21.9 0.0 5.8 4 2 0 5 5 5 5 Tetratricopeptide repeat TPR_6 PF13174.1 EIW67815.1 - 3.6e-21 74.1 14.8 0.012 16.0 0.0 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EIW67815.1 - 2e-13 49.9 7.1 0.038 13.8 0.3 6.7 1 1 5 7 7 7 6 Tetratricopeptide repeat Apc3 PF12895.2 EIW67815.1 - 2.1e-10 40.5 8.7 2.2e-05 24.5 0.8 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EIW67815.1 - 3.2e-06 26.4 9.3 0.038 13.0 1.5 4.8 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 EIW67815.1 - 0.00011 22.2 0.7 3 8.0 0.0 4.9 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIW67815.1 - 0.00035 20.4 11.7 0.46 10.4 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.3 EIW67815.1 - 0.0057 15.4 3.6 0.84 8.3 0.0 3.4 2 2 1 4 4 4 1 NMDA receptor-regulated protein 1 DUF2225 PF09986.4 EIW67815.1 - 0.013 14.9 1.1 5 6.5 0.0 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.4 EIW67815.1 - 0.2 11.6 8.0 4.5 7.1 0.2 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.1 EIW67815.1 - 0.35 9.9 13.2 4.7 6.2 0.2 4.7 1 1 2 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_3 PF07720.7 EIW67815.1 - 4 7.3 16.5 5 7.0 0.9 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 EIW67815.1 - 4.5 7.2 14.5 3.1 7.7 0.6 5.3 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain DnaJ PF00226.26 EIW67816.1 - 5.6e-18 64.4 1.4 1.7e-17 62.9 0.2 2.3 3 0 0 3 3 3 1 DnaJ domain Ni_hydr_CYTB PF01292.15 EIW67816.1 - 0.11 11.8 0.0 7.3 5.9 0.0 2.7 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 PepSY_TM_3 PF13706.1 EIW67816.1 - 4.4 6.8 5.4 11 5.5 3.8 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix Peptidase_M24 PF00557.19 EIW67817.1 - 6.9e-40 136.8 0.0 3.4e-39 134.5 0.0 1.9 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EIW67817.1 - 2.1e-20 73.5 0.0 2.3e-17 63.7 0.0 2.7 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain CN_hydrolase PF00795.17 EIW67818.1 - 1.6e-29 102.5 0.0 2.5e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EIW67818.1 - 1.3e-24 86.4 0.0 4.3e-24 84.7 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EIW67818.1 - 0.0014 18.2 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase Sec6 PF06046.8 EIW67819.1 - 7.5e-151 503.0 3.4 9.2e-151 502.7 2.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Bromodomain PF00439.20 EIW67820.1 - 3.6e-29 100.4 0.1 9.6e-16 57.4 0.1 2.8 2 1 0 2 2 2 2 Bromodomain WD40 PF00400.27 EIW67820.1 - 5.5e-20 70.4 11.4 2.9e-07 30.0 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF4407 PF14362.1 EIW67820.1 - 2.4 7.0 5.8 5 5.9 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.1 EIW67820.1 - 2.4 8.1 9.5 0.1 12.5 1.8 2.3 2 1 0 2 2 2 0 FlxA-like protein Aldo_ket_red PF00248.16 EIW67822.1 - 3.1e-53 180.4 0.0 3.7e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_2 PF00152.15 EIW67824.1 - 2.5e-102 342.1 0.0 1.6e-50 171.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIW67824.1 - 1.2e-10 41.1 0.1 2.7e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EIW67824.1 - 0.0023 17.5 0.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EIW67824.1 - 0.0075 15.4 0.1 0.14 11.3 0.0 2.8 3 1 0 3 3 3 1 tRNA synthetases class II core domain (F) TPR_11 PF13414.1 EIW67825.1 - 4.4e-20 71.0 6.7 4.7e-10 38.9 0.1 4.3 3 2 3 6 6 6 4 TPR repeat TPR_2 PF07719.12 EIW67825.1 - 2.6e-16 58.1 4.7 8.7e-06 25.2 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EIW67825.1 - 1.6e-15 55.9 0.1 4.7e-07 29.1 0.0 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW67825.1 - 2.7e-10 39.5 2.1 0.036 14.2 0.1 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW67825.1 - 1.7e-09 37.8 0.8 0.16 12.3 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW67825.1 - 3.2e-09 37.2 15.6 0.00018 22.1 0.1 5.3 4 1 1 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW67825.1 - 7.4e-08 31.6 2.0 0.0025 17.4 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW67825.1 - 1.3e-07 31.4 16.0 0.00042 20.1 0.1 5.4 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 EIW67825.1 - 1.3e-07 30.8 2.1 0.0061 16.2 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW67825.1 - 5.3e-07 29.7 11.5 0.00079 19.8 0.0 5.3 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIW67825.1 - 0.00023 20.9 0.5 0.0051 16.6 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIW67825.1 - 0.00076 19.5 2.9 0.33 11.0 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 EIW67825.1 - 0.0033 17.2 0.2 2.9 7.8 0.0 3.5 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_5 PF12688.2 EIW67825.1 - 0.0043 17.0 0.1 0.085 12.8 0.0 2.6 2 0 0 2 2 2 1 Tetratrico peptide repeat TPR_3 PF07720.7 EIW67825.1 - 0.012 15.4 0.0 1.5 8.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 EIW67825.1 - 0.12 11.7 0.0 1.7 7.9 0.0 2.6 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 EIW67825.1 - 0.34 11.4 9.1 18 6.0 0.0 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIW67825.1 - 0.74 9.8 15.9 0.55 10.2 0.3 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Diphtheria_T PF02764.9 EIW67826.1 - 4 7.1 6.0 3.2 7.4 1.9 2.1 2 0 0 2 2 2 0 Diphtheria toxin, T domain PDH PF02153.12 EIW67827.1 - 2.4e-14 52.8 0.0 3.8e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EIW67827.1 - 1.5e-06 28.5 0.1 5.9e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EIW67827.1 - 1.8e-05 24.6 0.0 3.3e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EIW67827.1 - 0.00023 20.3 0.0 0.00049 19.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EIW67827.1 - 0.00039 20.5 0.0 0.00083 19.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EIW67827.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 EIW67827.1 - 0.044 13.6 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 ThiF family ApbA PF02558.11 EIW67827.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA COX4 PF02936.9 EIW67828.1 - 1.1e-28 99.7 0.0 1.4e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV ATP-synt_C PF00137.16 EIW67829.1 - 3.4e-31 106.9 31.3 2.2e-18 65.9 8.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C zf-C2H2_4 PF13894.1 EIW67830.1 - 2.6e-05 24.2 7.8 0.72 10.3 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW67830.1 - 0.0032 17.7 5.7 5.4 7.5 0.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type adh_short PF00106.20 EIW67834.1 - 4.7e-22 78.6 0.0 6.4e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW67834.1 - 6.6e-13 48.9 0.0 9.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW67834.1 - 9.3e-09 35.1 0.0 1.9e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF2703 PF10865.3 EIW67834.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) CENP-F_leu_zip PF10473.4 EIW67835.1 - 0.054 13.3 1.1 0.13 12.1 0.3 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_L36 PF00444.13 EIW67836.1 - 7.4e-19 67.4 9.8 1.1e-18 66.8 6.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Fungal_trans PF04082.13 EIW67837.1 - 8.6e-10 37.9 0.4 2.8e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EIW67837.1 - 3.7e-07 30.1 10.3 0.0033 17.6 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW67837.1 - 0.0004 20.5 0.8 0.0004 20.5 0.5 2.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW67837.1 - 0.0022 18.2 10.5 0.032 14.5 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW67837.1 - 0.026 14.4 0.3 0.061 13.2 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Raptor_N PF14538.1 EIW67838.1 - 1.9e-16 60.2 0.0 9e-16 58.0 0.0 2.2 1 1 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.17 EIW67838.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Caspase domain PI3_PI4_kinase PF00454.22 EIW67839.1 - 2e-33 115.8 0.0 3.5e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EIW67839.1 - 7.1e-06 25.3 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 EIW67839.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DUF4381 PF14316.1 EIW67840.1 - 0.0091 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) M_domain PF12938.2 EIW67840.1 - 0.51 10.1 4.2 0.66 9.7 2.9 1.2 1 0 0 1 1 1 0 M domain of GW182 DNA_pol3_chi PF04364.8 EIW67844.1 - 0.039 13.7 0.2 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III chi subunit, HolC OTU PF02338.14 EIW67845.1 - 4.9e-17 62.6 0.0 1.7e-16 60.9 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EIW67845.1 - 0.0001 21.7 0.0 0.0075 15.6 0.0 2.1 1 1 1 2 2 2 2 Peptidase C65 Otubain Motile_Sperm PF00635.21 EIW67846.1 - 1.4e-25 89.0 0.0 3.1e-25 87.9 0.0 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain FAD_binding_7 PF03441.9 EIW67847.1 - 2.3e-89 299.2 0.2 3.3e-89 298.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EIW67847.1 - 6.1e-36 123.6 0.0 1.2e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase CN_hydrolase PF00795.17 EIW67848.1 - 2e-11 43.5 0.0 9.8e-11 41.3 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1674 PF07896.7 EIW67849.1 - 6.8e-08 32.6 3.4 1.1e-07 31.9 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) AP_endonuc_2 PF01261.19 EIW67850.1 - 2.6e-25 88.9 0.0 3.6e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel XkdN PF08890.6 EIW67852.1 - 0.0094 15.6 1.3 0.02 14.6 0.9 1.5 1 0 0 1 1 1 1 Phage XkdN-like protein PBP PF01161.15 EIW67853.1 - 5e-17 62.1 0.0 8.3e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ADK PF00406.17 EIW67854.1 - 1.2e-60 203.7 0.0 1.4e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EIW67854.1 - 3.1e-14 52.3 0.0 7.1e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EIW67854.1 - 3.1e-07 30.3 0.0 4.9e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW67854.1 - 6.3e-05 23.7 0.0 9.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW67854.1 - 0.0052 15.8 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EIW67854.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIW67854.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Asp PF00026.18 EIW67855.1 - 8.8e-26 90.8 1.8 6.7e-25 88.0 1.3 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF2077 PF09850.4 EIW67855.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) KRTAP PF11759.3 EIW67856.1 - 7.4 6.9 19.1 1.6 9.0 9.8 2.1 2 0 0 2 2 2 0 Keratin-associated matrix Cyclin PF08613.6 EIW67858.1 - 1.1e-24 87.5 1.3 2.4e-24 86.4 0.0 2.2 2 1 0 2 2 2 1 Cyclin DUF4613 PF15390.1 EIW67858.1 - 0.39 8.8 4.7 0.55 8.3 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Ribonuc_red_sm PF00268.16 EIW67859.1 - 3.4e-118 393.7 1.6 4.1e-118 393.4 1.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain MutS_V PF00488.16 EIW67861.1 - 7.3e-75 251.3 0.0 1.3e-74 250.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIW67861.1 - 2.8e-40 138.2 0.1 6.3e-40 137.1 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EIW67861.1 - 1.2e-33 115.4 0.3 4.4e-33 113.6 0.1 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EIW67861.1 - 7.3e-11 42.2 0.0 1.9e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain II ABC_ATPase PF09818.4 EIW67861.1 - 0.0059 15.2 0.0 0.01 14.4 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 EIW67861.1 - 0.0086 15.5 0.0 0.024 14.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EIW67861.1 - 0.017 15.3 0.0 0.069 13.4 0.0 2.0 1 0 0 1 1 1 0 ABC transporter MutS_IV PF05190.13 EIW67861.1 - 0.019 15.1 0.1 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV AAA_23 PF13476.1 EIW67861.1 - 0.12 12.6 0.1 0.76 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0086 PF01868.11 EIW67862.1 - 4.3e-18 64.7 0.0 1e-16 60.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Gti1_Pac2 PF09729.4 EIW67863.1 - 2.3e-57 193.5 0.0 3.4e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family SNF2_N PF00176.18 EIW67865.1 - 6.8e-70 235.2 0.0 2e-69 233.6 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW67865.1 - 4e-17 61.8 0.0 1.3e-16 60.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIW67865.1 - 7.6e-08 31.5 1.1 1.3e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EIW67865.1 - 0.0062 16.0 0.0 0.064 12.7 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AP_endonuc_2 PF01261.19 EIW67867.1 - 3.2e-13 49.4 0.1 6.2e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Zn_clus PF00172.13 EIW67868.1 - 4.6e-07 29.6 10.1 7.5e-07 28.9 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sigma70_r1_2 PF00140.15 EIW67869.1 - 0.1 12.2 1.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 MerR_1 PF13411.1 EIW67869.1 - 0.29 10.9 1.3 0.53 10.0 0.1 2.1 3 0 0 3 3 3 0 MerR HTH family regulatory protein zf-CCHC PF00098.18 EIW67870.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW67870.1 - 0.35 11.1 8.0 0.092 12.9 3.4 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW67870.1 - 0.63 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW67871.1 - 0.1 12.0 0.1 0.24 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) DUF2562 PF10814.3 EIW67872.1 - 0.037 13.9 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) Med25_SD1 PF11235.3 EIW67872.1 - 0.039 14.2 2.0 0.07 13.4 1.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 Ribosomal_L39 PF00832.15 EIW67872.1 - 0.93 9.0 9.3 5.2 6.6 0.6 4.1 4 1 0 4 4 4 0 Ribosomal L39 protein MFS_1 PF07690.11 EIW67873.1 - 3.3e-37 128.0 33.5 3.3e-37 128.0 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW67873.1 - 2.4e-10 39.5 23.2 1.1e-08 34.1 16.1 3.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EIW67873.1 - 0.00012 20.4 3.8 0.00023 19.5 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) IF4E PF01652.13 EIW67875.1 - 2.1e-31 108.6 0.0 2.7e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Zip PF02535.17 EIW67875.1 - 0.04 12.9 3.7 0.051 12.5 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EIW67875.1 - 0.11 11.8 11.4 0.15 11.4 7.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SMI1_KNR4 PF09346.5 EIW67876.1 - 8.9e-26 90.4 0.0 1.5e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Pkinase PF00069.20 EIW67878.1 - 2.5e-72 243.1 0.0 6.7e-72 241.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67878.1 - 3e-38 131.3 0.0 1e-36 126.3 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EIW67878.1 - 3e-17 61.7 0.1 5.3e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EIW67878.1 - 9.8e-06 24.7 0.0 2.2e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIW67878.1 - 1.4e-05 24.2 0.2 2.7e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW67878.1 - 8.4e-05 22.4 0.0 0.00029 20.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW67878.1 - 0.00076 18.8 0.0 0.0031 16.8 0.0 1.9 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.4 EIW67878.1 - 0.028 13.7 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WaaY PF06176.6 EIW67878.1 - 0.031 13.5 0.2 0.051 12.7 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) EcKinase PF02958.15 EIW67878.1 - 0.16 11.0 0.1 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Seadorna_VP7 PF07387.6 EIW67878.1 - 0.35 9.6 0.0 0.54 9.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 AhpC-TSA_2 PF13911.1 EIW67879.1 - 6.4e-08 32.5 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EIW67879.1 - 0.0022 17.6 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW67879.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.1 EIW67879.1 - 0.084 13.0 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like Alpha-amylase PF00128.19 EIW67880.1 - 1.9e-61 208.1 0.0 2.6e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EIW67880.1 - 1.8e-14 53.5 0.0 3.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Sdh5 PF03937.11 EIW67881.1 - 6.1e-23 80.3 0.6 8.3e-23 79.8 0.4 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Transaldolase PF00923.14 EIW67883.1 - 3.1e-97 325.1 0.0 3.6e-97 324.9 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Glyco_hydro_47 PF01532.15 EIW67884.1 - 4.6e-122 407.9 0.0 5.6e-122 407.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 EIW67884.1 - 1.2e-05 24.8 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PA domain PHY PF00360.15 EIW67886.1 - 3.7e-31 107.6 0.0 9.1e-31 106.4 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EIW67886.1 - 1.9e-18 66.2 1.1 3.1e-18 65.4 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIW67886.1 - 3.8e-16 59.0 0.1 8.7e-16 57.9 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 EIW67886.1 - 2.7e-14 53.5 0.0 6.7e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.20 EIW67886.1 - 1.8e-05 24.6 1.9 5.2e-05 23.1 1.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EIW67886.1 - 0.013 15.9 0.0 0.042 14.2 0.0 1.9 1 0 0 1 1 1 0 PAS fold OKR_DC_1_N PF03709.10 EIW67886.1 - 0.078 13.0 0.1 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Ribosomal_S7 PF00177.16 EIW67887.1 - 6e-40 136.2 1.0 7.2e-40 135.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RhoGAP PF00620.22 EIW67888.1 - 1.4e-11 44.2 0.0 2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain His_Phos_1 PF00300.17 EIW67889.1 - 9.4e-24 84.2 0.0 2.8e-23 82.7 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4448 PF14610.1 EIW67890.1 - 1.4e-06 27.9 0.5 3.5e-06 26.6 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EIW67890.1 - 6.7e-05 23.2 2.2 0.00022 21.6 1.5 1.9 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EIW67892.1 - 9.9e-05 21.9 1.9 0.00023 20.7 1.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF912 PF06024.7 EIW67892.1 - 0.1 12.6 0.2 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EIW67892.1 - 0.44 10.1 7.4 1.1 8.7 5.1 1.6 1 1 0 1 1 1 0 Rifin/stevor family DUF605 PF04652.11 EIW67892.1 - 4.8 6.4 17.8 6.2 6.1 12.3 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 EIW67892.1 - 9.3 4.3 16.1 15 3.7 11.2 1.3 1 0 0 1 1 1 0 Transmembrane protein ATG16 PF08614.6 EIW67893.1 - 0.0078 16.0 1.4 0.017 14.9 1.0 1.6 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Dynamitin PF04912.9 EIW67893.1 - 0.0086 14.9 1.9 0.015 14.1 1.3 1.3 1 0 0 1 1 1 1 Dynamitin DUF4200 PF13863.1 EIW67893.1 - 0.012 15.5 0.9 0.026 14.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) FlgN PF05130.7 EIW67893.1 - 0.27 11.4 5.6 0.57 10.4 3.9 1.5 1 0 0 1 1 1 0 FlgN protein Snapin_Pallidin PF14712.1 EIW67893.1 - 0.97 9.7 6.9 3.2 8.1 0.4 2.4 1 1 1 2 2 2 0 Snapin/Pallidin DUF972 PF06156.8 EIW67893.1 - 2.7 8.4 4.5 6.5 7.1 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EIW67893.1 - 6 6.7 5.6 2.8 7.8 0.3 2.8 2 1 1 3 3 3 0 Basic region leucine zipper Epimerase PF01370.16 EIW67895.1 - 3.1e-12 46.4 0.0 3.5e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW67895.1 - 2.2e-09 37.5 0.0 5.5e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW67895.1 - 0.00023 19.9 0.0 0.00046 18.9 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIW67895.1 - 0.00062 19.7 0.0 0.0016 18.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIW67895.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain ubiquitin PF00240.18 EIW67896.1 - 2.4e-202 654.7 39.2 2.1e-33 113.5 0.6 6.0 6 0 0 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.3 EIW67896.1 - 7.1e-116 378.0 35.7 8.2e-19 67.0 0.5 6.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIW67896.1 - 1.2e-34 118.4 20.4 0.00028 21.0 0.1 8.0 6 6 0 6 6 6 6 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIW67896.1 - 1.7e-31 109.1 5.2 0.0014 18.3 0.0 6.0 6 0 0 6 6 6 6 Telomere stability and silencing DUF2407 PF10302.4 EIW67896.1 - 2.4e-19 69.3 7.3 0.23 11.6 0.0 6.2 1 1 4 6 6 6 6 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EIW67896.1 - 2.6e-19 69.1 8.4 0.23 11.3 0.0 7.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EIW67896.1 - 7.2e-16 58.0 0.0 2.6 8.1 0.0 6.9 6 0 0 6 6 6 6 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EIW67896.1 - 2.9e-08 33.4 12.7 8.2 6.4 0.0 6.2 6 0 0 6 6 6 6 GLUT4 regulating protein TUG FlgD_ig PF13860.1 EIW67896.1 - 4.8e-06 26.2 11.7 23 4.7 0.0 6.2 6 0 0 6 6 6 0 FlgD Ig-like domain Big_3_3 PF13750.1 EIW67896.1 - 2e-05 24.0 0.1 82 2.5 0.0 5.7 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 EIW67896.1 - 0.00013 22.2 2.8 1.7e+02 2.6 0.0 6.0 6 0 0 6 6 6 0 ACT domain Plexin_cytopl PF08337.7 EIW67896.1 - 0.00016 20.1 23.6 4 5.6 0.2 7.8 7 5 0 7 7 7 5 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.6 EIW67896.1 - 0.03 14.2 47.6 5.5 7.0 1.2 6.4 6 0 0 6 6 6 0 Tash protein PEST motif GABP-alpha PF11620.3 EIW67896.1 - 0.04 13.9 14.4 83 3.2 0.1 5.9 6 0 0 6 6 6 0 GA-binding protein alpha chain FERM_N PF09379.5 EIW67896.1 - 0.6 10.2 22.7 75 3.4 0.1 8.1 6 6 0 6 6 6 0 FERM N-terminal domain DUF3781 PF12636.2 EIW67896.1 - 1.8 8.5 15.0 1.7e+02 2.2 0.1 5.9 6 0 0 6 6 6 0 Protein of unknown function (DUF3781) DUF2414 PF10309.4 EIW67897.1 - 1e-07 31.4 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 EIW67897.1 - 8.8e-05 22.4 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 RNA binding domain DUF4652 PF15525.1 EIW67897.1 - 0.13 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) AIP3 PF03915.8 EIW67898.1 - 1e-101 340.9 5.1 1.3e-101 340.6 3.5 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 WXG100 PF06013.7 EIW67898.1 - 3.8 7.5 9.7 5.3 7.1 0.1 4.1 3 1 1 4 4 4 0 Proteins of 100 residues with WXG ArsA_ATPase PF02374.10 EIW67899.1 - 1.5e-109 365.7 0.0 1.8e-109 365.5 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EIW67899.1 - 7.3e-15 54.8 0.0 1.1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIW67899.1 - 1.3e-07 31.7 0.0 4e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EIW67899.1 - 2e-05 23.9 0.1 4.6e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EIW67899.1 - 0.00031 20.2 0.0 0.0023 17.4 0.0 2.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EIW67899.1 - 0.00059 19.2 0.0 0.0017 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW67899.1 - 0.0011 18.7 0.0 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain YhjQ PF06564.7 EIW67899.1 - 0.015 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein VirC1 PF07015.6 EIW67899.1 - 0.017 14.2 0.1 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein RNA_helicase PF00910.17 EIW67899.1 - 0.038 14.1 0.0 0.79 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 EIW67899.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MipZ PF09140.6 EIW67899.1 - 0.12 11.4 0.0 0.25 10.3 0.0 1.5 2 0 0 2 2 2 0 ATPase MipZ SNF2_N PF00176.18 EIW67900.1 - 1.1e-63 214.7 0.8 1.6e-63 214.3 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW67900.1 - 5e-11 42.3 0.0 1.2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EIW67900.1 - 7.5e-09 35.1 7.3 1.4e-08 34.3 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW67900.1 - 2.3e-08 33.5 8.7 4.8e-08 32.5 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW67900.1 - 2.2e-07 30.7 10.0 5.5e-07 29.5 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW67900.1 - 2.8e-07 30.2 10.4 7.5e-07 28.8 7.2 1.8 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.10 EIW67900.1 - 1.1e-05 25.4 0.1 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 EIW67900.1 - 0.00042 19.9 7.7 0.0009 18.9 5.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIW67900.1 - 0.0013 18.5 8.9 0.0043 16.8 6.3 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIW67900.1 - 0.0018 17.9 2.4 0.0018 17.9 1.7 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Cas_Cas1 PF01867.11 EIW67900.1 - 0.0037 16.3 0.0 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 CRISPR associated protein Cas1 Prok-RING_4 PF14447.1 EIW67900.1 - 8.2 6.0 9.1 18 4.9 0.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Mago-bind PF09282.5 EIW67901.1 - 0.086 12.4 0.2 0.26 10.8 0.1 1.8 1 0 0 1 1 1 0 Mago binding HEAT_EZ PF13513.1 EIW67901.1 - 0.26 11.8 2.3 6.9 7.3 0.1 2.9 3 0 0 3 3 3 0 HEAT-like repeat Ribosomal_S8 PF00410.14 EIW67902.1 - 7.5e-26 90.4 0.1 1e-25 90.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glyco_transf_22 PF03901.12 EIW67903.1 - 4.3e-72 243.4 20.7 5.9e-72 242.9 14.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4507 PF14964.1 EIW67904.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) SR-25 PF10500.4 EIW67905.1 - 0.43 10.0 10.3 0.79 9.1 7.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Proteasome PF00227.21 EIW67906.1 - 2.9e-29 101.7 0.0 3.8e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit GLTP PF08718.6 EIW67907.1 - 2.8e-39 134.5 0.0 3.6e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Cnd1 PF12717.2 EIW67908.1 - 2.7e-62 209.7 6.9 1.5e-58 197.5 0.1 4.0 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EIW67908.1 - 1.2e-47 161.7 0.9 2e-46 157.7 0.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EIW67908.1 - 2.2e-06 27.8 0.4 0.0091 16.2 0.0 4.7 4 1 0 4 4 4 1 HEAT repeats Adaptin_N PF01602.15 EIW67908.1 - 4.5e-06 25.2 12.9 0.0034 15.7 0.2 4.6 4 3 0 4 4 4 2 Adaptin N terminal region HEAT PF02985.17 EIW67908.1 - 0.0002 21.1 3.4 13 6.1 0.0 6.9 7 0 0 7 7 7 1 HEAT repeat YtzH PF14165.1 EIW67908.1 - 0.027 14.6 0.1 0.21 11.8 0.0 2.6 1 1 0 1 1 1 0 YtzH-like protein HEAT_EZ PF13513.1 EIW67908.1 - 0.052 14.0 7.2 1.9 9.0 0.1 5.3 5 1 1 6 6 6 0 HEAT-like repeat CBS PF00571.23 EIW67910.1 - 8.7e-08 31.8 0.0 0.0045 16.7 0.0 2.2 2 0 0 2 2 2 2 CBS domain ABC_membrane_2 PF06472.10 EIW67911.1 - 5.4e-82 275.0 0.1 2e-81 273.2 0.1 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EIW67911.1 - 7.2e-15 55.4 0.0 1.3e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.7 EIW67911.1 - 0.00085 18.4 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIW67911.1 - 0.0056 16.8 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIW67911.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW67911.1 - 0.014 16.2 0.0 0.032 15.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EIW67911.1 - 0.019 15.1 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EIW67911.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIW67911.1 - 0.039 13.7 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EIW67911.1 - 0.043 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 EIW67911.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIW67911.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF3584 PF12128.3 EIW67911.1 - 0.091 10.0 0.1 0.14 9.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_18 PF13238.1 EIW67911.1 - 0.14 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIW67911.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RabGAP-TBC PF00566.13 EIW67913.1 - 7e-53 179.2 0.1 1.1e-52 178.6 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ebola_NP PF05505.7 EIW67913.1 - 0.018 13.1 0.0 0.058 11.4 0.0 1.7 2 0 0 2 2 2 0 Ebola nucleoprotein APG6 PF04111.7 EIW67913.1 - 2.5 7.0 10.0 0.084 11.9 2.7 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 TFIID-31kDa PF02291.10 EIW67914.1 - 6.2e-31 106.8 0.0 7.8e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 EIW67914.1 - 0.00011 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated DUF1931 PF09123.6 EIW67914.1 - 0.068 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Histone PF00125.19 EIW67914.1 - 0.099 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TRAP_alpha PF03896.11 EIW67914.1 - 5.7 5.8 8.1 8 5.3 5.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BASP1 PF05466.7 EIW67915.1 - 0.65 9.7 8.7 1.2 8.8 6.0 1.4 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DUF4211 PF13926.1 EIW67916.1 - 3.8e-18 65.3 0.0 1.7e-17 63.2 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4211) Fasciclin PF02469.17 EIW67917.1 - 1e-17 64.3 0.0 4.8e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain RF-1 PF00472.15 EIW67918.1 - 9.1e-39 131.7 1.2 9.1e-39 131.7 0.8 2.1 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 EIW67918.1 - 1.7e-28 98.6 0.0 4.3e-28 97.3 0.0 1.7 1 0 0 1 1 1 1 PCRF domain T4SS PF07996.6 EIW67918.1 - 0.024 14.4 0.1 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion system proteins His_Phos_1 PF00300.17 EIW67919.1 - 1.3e-17 64.3 0.0 2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_transf_90 PF05686.7 EIW67920.1 - 1.4e-12 47.0 0.5 3.1e-11 42.6 0.3 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 90 WD40 PF00400.27 EIW67921.1 - 5.6e-27 92.5 7.4 1.1e-08 34.6 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EIW67921.1 - 0.0015 16.7 0.2 0.72 7.9 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Glyco_hydro_1 PF00232.13 EIW67922.1 - 1.3e-124 415.8 0.1 1.5e-124 415.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.13 EIW67922.1 - 3.8e-05 23.0 0.0 0.00025 20.3 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Methyltransf_31 PF13847.1 EIW67923.1 - 1.8e-16 60.0 0.0 9.9e-16 57.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW67923.1 - 1.5e-15 57.4 0.0 2.6e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW67923.1 - 9.4e-15 54.6 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW67923.1 - 3.8e-11 43.5 0.0 2.2e-10 41.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW67923.1 - 1.6e-07 31.6 0.0 3.7e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW67923.1 - 2.6e-07 31.0 0.0 9e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW67923.1 - 4.8e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW67923.1 - 7.5e-07 28.5 0.0 1.8e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EIW67923.1 - 6.2e-06 25.5 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_29 PF03141.11 EIW67923.1 - 3.3e-05 22.4 0.0 9.1e-05 20.9 0.0 1.6 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 EIW67923.1 - 9.8e-05 21.4 0.0 0.00026 20.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EIW67923.1 - 0.0002 21.3 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EIW67923.1 - 0.021 13.9 0.0 0.091 11.8 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 EIW67923.1 - 0.023 14.0 0.0 0.049 13.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 EIW67923.1 - 0.039 13.3 0.0 0.56 9.5 0.0 2.1 1 1 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 EIW67923.1 - 0.058 14.2 0.0 1.1 10.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EIW67924.1 - 2.9e-15 56.3 0.0 4.3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW67924.1 - 5.3e-15 55.6 0.0 9.9e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW67924.1 - 1.5e-13 50.6 0.0 4.7e-13 48.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW67924.1 - 3.7e-09 36.9 0.0 1.1e-08 35.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW67924.1 - 7e-09 36.2 0.0 4.9e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW67924.1 - 1.6e-07 31.6 0.0 3.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW67924.1 - 3.2e-07 30.3 0.0 7.8e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIW67924.1 - 0.00019 21.1 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 EIW67924.1 - 0.00033 19.8 0.0 0.00059 19.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 EIW67924.1 - 0.00072 18.0 0.0 0.0014 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 EIW67924.1 - 0.0013 17.9 0.0 0.018 14.1 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EIW67924.1 - 0.0023 17.0 0.0 0.0057 15.7 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EIW67924.1 - 0.0041 16.5 0.0 0.14 11.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EIW67924.1 - 0.0081 15.3 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 EIW67924.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EIW67924.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EIW67925.1 - 1.3e-14 54.1 0.0 6.5e-11 42.2 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EIW67925.1 - 8.5e-11 42.2 0.0 5.6e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EIW67925.1 - 8.6e-10 38.3 0.0 8.7e-09 35.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW67925.1 - 2.2e-07 31.4 0.0 1.5e-06 28.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW67925.1 - 4.3e-07 29.9 0.0 1.8e-06 27.9 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW67925.1 - 4.4e-06 27.0 0.0 0.00021 21.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW67925.1 - 3.8e-05 23.9 0.0 0.00013 22.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW67925.1 - 5.9e-05 22.3 0.0 0.0012 17.9 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EIW67925.1 - 0.00043 19.6 0.0 0.035 13.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EIW67925.1 - 0.0034 16.5 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EIW67925.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.10 EIW67925.1 - 0.013 15.1 0.0 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_4 PF02390.12 EIW67925.1 - 0.019 14.0 0.0 0.075 12.0 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.4 EIW67925.1 - 0.045 13.1 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.10 EIW67925.1 - 0.077 12.1 0.0 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_2 PF00891.13 EIW67925.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_29 PF03141.11 EIW67925.1 - 0.097 10.9 0.0 2.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.7 EIW67926.1 - 2.9e-16 59.7 0.0 8.5e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW67926.1 - 2.9e-15 56.3 0.0 5.8e-15 55.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW67926.1 - 2.9e-13 49.6 0.0 8e-13 48.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW67926.1 - 4.8e-10 40.0 0.1 2.4e-09 37.7 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW67926.1 - 5.3e-10 39.5 0.0 1.2e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW67926.1 - 9.2e-09 35.6 0.0 3.3e-08 33.9 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW67926.1 - 3.5e-08 33.4 0.0 7.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EIW67926.1 - 7.2e-08 31.2 0.0 2.1e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.10 EIW67926.1 - 2.2e-06 27.4 0.0 3.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 EIW67926.1 - 3.7e-05 22.9 0.0 0.00012 21.2 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EIW67926.1 - 0.0004 19.4 0.0 0.0016 17.5 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EIW67926.1 - 0.00052 19.1 0.0 0.00094 18.3 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EIW67926.1 - 0.00081 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EIW67926.1 - 0.0016 17.8 0.0 0.004 16.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EIW67926.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EIW67926.1 - 0.022 14.1 0.0 0.047 13.0 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW tRNA-synt_1 PF00133.17 EIW67926.1 - 0.065 11.2 0.0 0.098 10.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Methyltransf_11 PF08241.7 EIW67927.1 - 7.7e-16 58.3 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW67927.1 - 1.4e-15 57.2 0.0 2e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW67927.1 - 1.1e-14 54.4 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW67927.1 - 2e-11 44.2 0.0 3.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW67927.1 - 2.2e-11 44.3 0.0 5.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW67927.1 - 2.2e-09 37.6 0.0 4.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW67927.1 - 1.4e-08 34.1 0.0 2.9e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 EIW67927.1 - 9.3e-08 30.8 0.0 1.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 EIW67927.1 - 5.3e-07 28.8 0.1 3e-05 23.1 0.0 2.3 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EIW67927.1 - 1.1e-06 28.6 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIW67927.1 - 1.5e-06 27.5 0.0 3e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EIW67927.1 - 4.2e-05 23.0 0.0 7.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EIW67927.1 - 6.7e-05 22.1 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_16 PF10294.4 EIW67927.1 - 0.0016 17.8 0.1 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_8 PF05148.10 EIW67927.1 - 0.002 17.7 0.0 0.013 15.1 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.7 EIW67927.1 - 0.0045 16.3 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DUF938 PF06080.7 EIW67927.1 - 0.0086 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) FtsJ PF01728.14 EIW67927.1 - 0.03 14.2 0.0 0.067 13.1 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.10 EIW67927.1 - 0.046 12.8 0.0 0.14 11.3 0.0 1.6 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G PrmA PF06325.8 EIW67927.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_17 PF12692.2 EIW67927.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.6 1 1 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Methyltransf_11 PF08241.7 EIW67928.1 - 2e-15 57.0 0.0 3.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW67928.1 - 3.3e-15 56.1 0.0 5.2e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW67928.1 - 1.8e-11 43.8 0.0 8.1e-11 41.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW67928.1 - 1.9e-07 31.6 0.0 3.1e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW67928.1 - 5.7e-07 29.9 0.0 3.6e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIW67928.1 - 5.9e-05 22.8 0.0 8.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.1 EIW67928.1 - 0.00016 21.9 0.0 0.0005 20.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIW67928.1 - 0.00018 20.6 0.0 0.023 13.7 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EIW67928.1 - 0.00031 19.9 0.0 0.001 18.2 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 EIW67928.1 - 0.0018 16.6 0.0 0.0047 15.3 0.0 1.6 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EIW67928.1 - 0.0031 16.9 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIW67928.1 - 0.004 17.1 0.0 0.019 14.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIW67928.1 - 0.019 14.0 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EIW67928.1 - 0.026 13.7 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase MetW PF07021.7 EIW67928.1 - 0.041 13.2 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 EIW67928.1 - 0.047 12.8 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0258 PF06789.7 EIW67928.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF938 PF06080.7 EIW67928.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_3 PF01596.12 EIW67928.1 - 0.12 11.3 0.0 11 5.0 0.0 2.3 2 0 0 2 2 2 0 O-methyltransferase FtsJ PF01728.14 EIW67928.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EIW67928.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Acyl-CoA_dh_1 PF00441.19 EIW67929.1 - 1.5e-49 167.9 2.8 2.3e-49 167.3 2.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIW67929.1 - 8.8e-23 79.5 0.3 1.7e-22 78.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EIW67929.1 - 5.8e-19 68.7 0.1 1.3e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIW67929.1 - 1.5e-18 67.3 1.9 2.3e-18 66.7 1.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EIW67929.1 - 0.00017 21.0 0.4 0.00068 19.1 0.2 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DNA_pol_B PF00136.16 EIW67930.1 - 9e-145 483.0 0.6 1.5e-144 482.2 0.4 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EIW67930.1 - 3.7e-89 298.7 0.0 8.2e-89 297.6 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EIW67930.1 - 8.6e-22 76.9 8.1 8.6e-22 76.9 5.6 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 EIW67930.1 - 0.0031 16.2 3.3 0.0066 15.1 0.2 2.3 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 EIW67930.1 - 0.0045 16.5 0.1 0.0091 15.5 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_A_exo1 PF01612.15 EIW67930.1 - 0.036 13.5 0.2 0.13 11.7 0.1 1.9 2 0 0 2 2 2 0 3'-5' exonuclease RNase_H_2 PF13482.1 EIW67930.1 - 0.053 13.3 0.2 0.19 11.5 0.2 2.1 1 1 0 1 1 1 0 RNase_H superfamily HypA PF01155.14 EIW67930.1 - 7.2 6.3 7.3 10 5.8 0.2 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EIW67930.1 - 8.9 6.2 7.9 67 3.4 5.5 2.3 1 1 0 1 1 1 0 Double zinc ribbon Asn_synthase PF00733.16 EIW67931.1 - 2.9e-47 161.2 0.0 4.2e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EIW67931.1 - 0.0067 16.1 0.0 0.021 14.5 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain Fork_head PF00250.13 EIW67932.1 - 2.3e-22 78.8 0.0 7.1e-22 77.2 0.0 1.8 1 0 0 1 1 1 1 Fork head domain TSSC4 PF15264.1 EIW67932.1 - 0.24 11.8 5.3 2.7 8.4 3.6 2.8 1 1 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 HORMA PF02301.13 EIW67933.1 - 4.7e-19 68.6 0.0 1.2e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 HORMA domain PolC_DP2 PF03833.8 EIW67933.1 - 0.21 9.1 3.9 0.27 8.8 2.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 EIW67933.1 - 1.7 8.4 11.7 3.6 7.3 8.1 1.6 1 0 0 1 1 1 0 PHD-finger Choline_transpo PF04515.7 EIW67934.1 - 2.6e-43 148.0 0.2 3.4e-43 147.6 0.1 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter DJ-1_PfpI PF01965.19 EIW67935.1 - 1.6e-21 76.2 0.1 3.3e-21 75.2 0.1 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EIW67935.1 - 1.6e-10 40.3 1.0 3.1e-10 39.4 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family Metalloenzyme PF01676.13 EIW67937.1 - 6.4e-78 261.6 1.2 7.8e-78 261.3 0.8 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EIW67937.1 - 3.2e-72 242.4 0.1 4.5e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Sulfatase PF00884.18 EIW67937.1 - 4.4e-06 26.1 0.0 1.5e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EIW67937.1 - 2.2e-05 23.9 0.0 4.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.7 EIW67937.1 - 0.03 14.0 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 PglZ domain Phage_fiber_2 PF03406.8 EIW67937.1 - 0.19 11.4 0.7 0.35 10.5 0.5 1.4 1 0 0 1 1 1 0 Phage tail fibre repeat TPR_11 PF13414.1 EIW67938.1 - 3.1e-16 58.7 2.4 6.3e-07 28.9 0.4 3.0 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 EIW67938.1 - 3.2e-11 42.3 1.0 1.5e-07 30.6 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW67938.1 - 4e-08 32.5 0.4 0.00012 21.7 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW67938.1 - 0.00089 19.1 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW67938.1 - 0.0012 18.5 0.1 0.13 12.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIW67938.1 - 0.0033 17.0 0.1 0.037 13.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIW67938.1 - 0.03 14.5 0.5 1.7 9.0 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW67938.1 - 0.055 14.1 3.6 0.14 12.8 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIW67938.1 - 0.39 11.0 2.2 0.84 10.0 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma70_ner PF04546.8 EIW67938.1 - 7 6.2 14.4 0.51 9.9 2.7 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Glycos_transf_4 PF00953.16 EIW67939.1 - 8.3e-33 113.4 5.7 1.9e-32 112.2 4.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 4 Aconitase PF00330.15 EIW67940.1 - 3.8e-72 243.2 0.2 4.3e-46 157.3 0.0 3.0 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIW67940.1 - 2.3e-18 66.5 0.1 4.7e-18 65.5 0.1 1.6 1 1 0 1 1 1 1 Aconitase C-terminal domain NPCBM_assoc PF10633.4 EIW67940.1 - 0.0014 18.6 0.2 1.5 8.9 0.0 2.5 2 0 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase Glyco_hydro_18 PF00704.23 EIW67941.1 - 3.5e-36 125.3 6.0 4.5e-36 125.0 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 EF-hand_4 PF12763.2 EIW67944.1 - 1.9e-29 101.4 0.0 4.5e-14 52.0 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EIW67944.1 - 1.3e-06 28.3 0.0 0.00052 20.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair Macoilin PF09726.4 EIW67944.1 - 7.2e-06 24.5 13.1 8.9e-06 24.2 9.1 1.1 1 0 0 1 1 1 1 Transmembrane protein MAD PF05557.8 EIW67944.1 - 4.3e-05 21.8 15.6 6.9e-05 21.1 10.8 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein EF-hand_1 PF00036.27 EIW67944.1 - 0.00043 19.3 0.7 0.47 9.8 0.0 3.5 3 0 0 3 3 3 1 EF hand TMCO5 PF14992.1 EIW67944.1 - 0.00052 19.2 22.5 0.00079 18.6 15.6 1.2 1 0 0 1 1 1 1 TMCO5 family DUF1664 PF07889.7 EIW67944.1 - 0.0047 16.7 8.4 0.0047 16.7 5.8 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) EF-hand_8 PF13833.1 EIW67944.1 - 0.017 14.6 0.1 0.65 9.6 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair CENP-H PF05837.7 EIW67944.1 - 0.081 13.1 19.6 1.1 9.4 6.0 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.4 EIW67944.1 - 0.1 12.4 30.5 0.019 14.8 8.7 2.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.1 EIW67944.1 - 0.3 11.0 29.6 0.064 13.2 14.5 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 EIW67944.1 - 0.37 9.9 8.8 0.47 9.5 4.7 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF3450 PF11932.3 EIW67944.1 - 0.4 9.8 23.8 0.84 8.8 8.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) EF-hand_6 PF13405.1 EIW67944.1 - 0.5 10.3 3.3 54 4.0 0.1 3.7 4 0 0 4 4 3 0 EF-hand domain DUF848 PF05852.6 EIW67944.1 - 0.52 10.1 19.5 0.27 11.1 5.3 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TMPIT PF07851.8 EIW67944.1 - 0.61 9.1 14.8 0.42 9.6 1.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein IncA PF04156.9 EIW67944.1 - 1.1 8.7 25.9 0.76 9.3 15.2 2.1 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 EIW67944.1 - 1.5 7.9 25.6 0.049 12.8 12.0 2.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Nup54 PF13874.1 EIW67944.1 - 3.2 7.4 16.7 0.45 10.1 5.9 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CALCOCO1 PF07888.6 EIW67944.1 - 3.6 5.7 21.7 5.4 5.1 15.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Mod_r PF07200.8 EIW67944.1 - 4.6 7.1 23.2 0.081 12.8 6.8 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ERM PF00769.14 EIW67944.1 - 5.7 6.3 29.4 2.3 7.6 18.5 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Syntaxin PF00804.20 EIW67944.1 - 7.3 6.8 19.9 0.49 10.5 5.6 2.3 1 1 1 2 2 2 0 Syntaxin ATG16 PF08614.6 EIW67944.1 - 8.6 6.1 29.0 1.5 8.5 13.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 EIW67944.1 - 9.1 6.0 27.5 6.9 6.4 2.9 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.6 EIW67944.1 - 9.7 3.5 11.4 1.7 6.0 4.0 1.8 1 1 1 2 2 2 0 Prominin RPN7 PF10602.4 EIW67945.1 - 2.8e-51 173.4 1.5 4.8e-51 172.6 1.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EIW67945.1 - 1.2e-16 60.9 0.4 9.6e-16 58.0 0.0 2.5 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EIW67945.1 - 0.0007 19.3 0.1 0.0079 15.9 0.0 2.3 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIW67945.1 - 0.0034 16.9 0.3 0.0063 16.0 0.2 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF4007 PF13182.1 EIW67945.1 - 0.063 12.0 0.1 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4007) FeoC PF09012.5 EIW67945.1 - 0.12 12.0 0.2 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator Chs3p PF12271.3 EIW67946.1 - 2.6e-117 391.0 22.9 3e-117 390.8 15.9 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit tRNA_int_end_N2 PF12928.2 EIW67947.1 - 4.8e-13 48.3 0.0 9.4e-13 47.4 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EIW67947.1 - 0.0069 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Abhydrolase_6 PF12697.2 EIW67949.1 - 4.3e-10 39.8 0.1 7.1e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW67949.1 - 0.0032 17.0 0.1 0.015 14.8 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold MBF1 PF08523.5 EIW67950.1 - 2.9e-09 36.8 0.4 2.9e-09 36.8 0.3 1.8 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EIW67950.1 - 0.034 14.0 0.1 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix DALR_2 PF09190.6 EIW67950.1 - 0.081 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 DALR domain PH PF00169.24 EIW67951.1 - 5e-08 33.0 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 PH domain Pro_isomerase PF00160.16 EIW67952.1 - 1.6e-29 103.0 0.0 1.8e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2431 PF10354.4 EIW67953.1 - 1.2e-37 129.4 0.0 4.4e-37 127.6 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF2431) DUF3446 PF11928.3 EIW67953.1 - 0.026 14.7 0.2 0.026 14.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) NAP PF00956.13 EIW67953.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.3 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) RasGAP PF00616.14 EIW67954.1 - 2.7e-54 183.8 0.0 8.5e-54 182.2 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EIW67954.1 - 1.7e-33 115.2 0.0 6.4e-33 113.4 0.0 2.0 1 0 0 1 1 1 1 RasGAP C-terminus Herpes_UL14 PF03580.9 EIW67954.1 - 0.04 13.7 2.7 0.13 12.0 1.9 1.8 1 0 0 1 1 1 0 Herpesvirus UL14-like protein DUF972 PF06156.8 EIW67954.1 - 2.9 8.2 8.1 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) TMA7 PF09072.5 EIW67955.1 - 5e-18 65.3 13.2 8.5e-18 64.5 9.1 1.3 1 0 0 1 1 1 1 Translation machinery associated TMA7 UPF0154 PF03672.8 EIW67956.1 - 1.1 8.9 2.3 12 5.6 0.3 2.6 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0154) DLH PF01738.13 EIW67957.1 - 2.5e-26 92.3 0.0 2.9e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW67957.1 - 8.3e-09 35.3 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW67957.1 - 0.014 15.2 0.0 0.054 13.3 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family BAAT_C PF08840.6 EIW67957.1 - 0.024 14.3 0.0 0.079 12.6 0.0 1.7 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EIW67957.1 - 0.055 13.0 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold RRM_1 PF00076.17 EIW67959.1 - 1.7e-11 43.5 0.0 3.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW67959.1 - 3.6e-11 42.8 0.0 7.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Borrelia_P83 PF05262.6 EIW67959.1 - 0.56 8.4 7.1 0.78 7.9 4.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NARP1 PF12569.3 EIW67959.1 - 0.81 8.3 10.8 1.2 7.8 7.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 OCD_Mu_crystall PF02423.10 EIW67960.1 - 2.5e-23 82.3 0.0 3.6e-21 75.2 0.0 2.1 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family PHD PF00628.24 EIW67961.1 - 1.1e-07 31.4 8.3 1.7e-07 30.7 5.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EIW67961.1 - 0.00077 18.7 4.1 0.0013 18.0 2.9 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EIW67961.1 - 0.063 13.0 2.4 0.13 12.0 1.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EIW67961.1 - 0.41 9.9 1.7 0.77 9.0 1.2 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Zn_Tnp_IS1595 PF12760.2 EIW67961.1 - 0.57 10.0 3.3 1.3 8.8 2.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain MDM31_MDM32 PF08118.6 EIW67962.1 - 1.9e-132 442.2 0.0 2.7e-132 441.8 0.0 1.2 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins 4HBT PF03061.17 EIW67962.1 - 0.074 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Thioesterase superfamily Pkinase PF00069.20 EIW67963.1 - 7e-17 61.4 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EIW67963.1 - 1.4e-11 43.7 14.9 3e-05 23.7 0.2 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat HEAT PF02985.17 EIW67963.1 - 1.5e-08 33.9 7.4 0.058 13.5 0.1 5.8 5 0 0 5 5 5 3 HEAT repeat Pkinase_Tyr PF07714.12 EIW67963.1 - 5.6e-06 25.6 0.0 0.023 13.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_2 PF13646.1 EIW67963.1 - 1.4e-05 25.2 1.7 0.19 12.0 0.0 3.5 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EIW67963.1 - 0.26 11.8 5.3 4.1 8.0 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat HpcH_HpaI PF03328.9 EIW67964.1 - 4.7e-37 127.0 0.0 5.5e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 EIW67964.1 - 0.055 12.3 0.1 5 5.9 0.0 2.5 2 1 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain Lipase_GDSL PF00657.17 EIW67964.1 - 0.06 13.1 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Amidohydro_2 PF04909.9 EIW67965.1 - 4.2e-15 56.0 0.3 1.8e-14 53.9 0.2 1.8 1 1 0 1 1 1 1 Amidohydrolase 2-Hacid_dh_C PF02826.14 EIW67966.1 - 4.3e-46 156.2 0.0 6.5e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW67966.1 - 1.2e-16 60.3 0.0 1.4e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GFO_IDH_MocA PF01408.17 EIW67966.1 - 0.022 15.2 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox PF00070.22 EIW67966.1 - 0.077 13.4 0.2 0.2 12.1 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EIW67967.1 - 2.4e-35 121.8 27.0 2.4e-35 121.8 18.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CRAL_TRIO PF00650.15 EIW67968.1 - 4e-22 78.4 0.0 5.8e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIW67968.1 - 9.1e-09 35.3 0.1 3.6e-08 33.4 0.0 2.1 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EIW67968.1 - 0.015 15.2 0.0 0.62 9.9 0.0 2.8 3 0 0 3 3 3 0 Divergent CRAL/TRIO domain Myb_DNA-binding PF00249.26 EIW67969.1 - 0.00011 22.1 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW67969.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.5 1 1 0 1 1 1 0 Myb-like DNA-binding domain ORC6 PF05460.8 EIW67969.1 - 0.11 11.6 2.1 0.12 11.4 1.4 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Sel1 PF08238.7 EIW67970.1 - 6.7e-14 52.0 8.3 4.8e-07 30.1 0.2 4.4 4 0 0 4 4 4 3 Sel1 repeat DUF3246 PF11596.3 EIW67970.1 - 0.011 15.0 2.7 0.027 13.7 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Pkinase PF00069.20 EIW67971.1 - 2.2e-71 240.0 0.0 3e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW67971.1 - 2.4e-36 125.1 0.0 3.7e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW67971.1 - 6.5e-06 25.3 0.0 9.2e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW67971.1 - 0.00069 19.4 0.1 0.003 17.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW67971.1 - 0.024 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIW67971.1 - 0.026 14.0 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Velvet PF11754.3 EIW67972.1 - 2.3e-32 112.2 0.0 9.9e-32 110.1 0.0 1.9 1 1 0 1 1 1 1 Velvet factor SGT1 PF07093.6 EIW67973.1 - 1e-151 506.2 16.8 2.3e-151 505.1 10.7 2.1 1 1 0 1 1 1 1 SGT1 protein Peptidase_S26 PF10502.4 EIW67974.1 - 3.7e-09 36.2 0.0 6.7e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EIW67974.1 - 1.1e-08 34.6 0.0 3e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S10 PF00450.17 EIW67976.1 - 1.5e-104 350.4 0.2 1.9e-104 350.1 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIW67976.1 - 0.015 15.1 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family GMP_synt_C PF00958.17 EIW67977.1 - 2.1e-40 136.3 0.1 3.9e-40 135.4 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EIW67977.1 - 1.3e-33 116.0 0.1 2.1e-33 115.4 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EIW67977.1 - 6.8e-11 41.5 0.5 3.1e-06 26.2 0.1 2.5 2 1 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EIW67977.1 - 2.4e-10 40.2 0.2 4.3e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase C26 Asn_synthase PF00733.16 EIW67977.1 - 0.00018 21.1 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EIW67977.1 - 0.00095 17.8 0.1 0.0016 17.0 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 EIW67977.1 - 0.0016 17.9 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 EIW67977.1 - 0.0062 15.8 0.0 0.075 12.2 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 EIW67977.1 - 0.014 14.4 0.1 0.022 13.7 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase DUF2392 PF10288.4 EIW67977.1 - 0.042 14.1 0.0 0.087 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) HOASN PF14515.1 EIW67977.1 - 0.053 13.8 0.2 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices ATP_bind_3 PF01171.15 EIW67977.1 - 0.064 12.7 0.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 PP-loop family BTB PF00651.26 EIW67978.1 - 0.00013 21.8 0.1 0.43 10.5 0.0 2.8 2 1 0 3 3 3 2 BTB/POZ domain BTB PF00651.26 EIW67979.1 - 0.00015 21.7 0.1 0.00031 20.7 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EIW67980.1 - 6.2e-17 61.5 0.1 1.8e-09 37.5 0.1 3.7 3 0 0 3 3 3 3 BTB/POZ domain Skp1_POZ PF03931.10 EIW67980.1 - 0.064 13.3 1.6 0.53 10.4 0.1 2.7 2 1 1 3 3 3 0 Skp1 family, tetramerisation domain BTB PF00651.26 EIW67981.1 - 2.7e-10 40.1 0.1 4e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Pirin PF02678.11 EIW67982.1 - 2.6e-31 107.6 0.0 5.3e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EIW67982.1 - 1.9e-23 82.5 0.0 6.2e-22 77.6 0.0 2.4 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EIW67982.1 - 0.00012 21.5 0.4 0.0014 18.0 0.1 2.4 2 0 0 2 2 2 1 Cupin domain Asp PF00026.18 EIW67983.1 - 4.3e-49 167.4 7.9 7.4e-32 110.8 0.8 2.1 1 1 0 2 2 2 2 Eukaryotic aspartyl protease Ycf1 PF05758.7 EIW67983.1 - 3e-05 22.0 2.5 3.5e-05 21.7 1.7 1.1 1 0 0 1 1 1 1 Ycf1 TAXi_N PF14543.1 EIW67983.1 - 0.00027 20.9 2.4 0.0022 17.9 0.8 2.5 2 1 0 2 2 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW67983.1 - 0.037 14.5 1.0 3.5 8.1 0.1 3.6 3 1 0 3 3 3 0 Aspartyl protease Spore_coat_CotO PF14153.1 EIW67983.1 - 0.076 12.4 16.6 0.17 11.2 11.5 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 EIW67983.1 - 0.084 11.3 14.4 0.13 10.6 10.0 1.2 1 0 0 1 1 1 0 Daxx Family SprA-related PF12118.3 EIW67983.1 - 0.091 12.0 14.0 0.15 11.4 9.7 1.3 1 0 0 1 1 1 0 SprA-related family Zip PF02535.17 EIW67983.1 - 0.15 11.0 1.0 0.29 10.1 0.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter MIP-T3 PF10243.4 EIW67983.1 - 0.15 10.4 33.3 0.23 9.8 23.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDHD PF02862.12 EIW67983.1 - 0.29 10.8 14.1 0.63 9.8 9.8 1.5 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 EIW67983.1 - 0.34 10.2 22.1 0.92 8.8 15.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paramyxo_ncap PF00973.14 EIW67983.1 - 0.56 8.8 6.0 0.82 8.2 4.1 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF2201_N PF13203.1 EIW67983.1 - 0.64 9.1 8.0 1.1 8.4 5.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2413 PF10310.4 EIW67983.1 - 0.64 8.7 18.5 1.1 7.9 12.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Serinc PF03348.10 EIW67983.1 - 0.69 8.5 2.0 0.93 8.1 1.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) FLO_LFY PF01698.11 EIW67983.1 - 0.83 8.4 11.5 5.6 5.6 8.0 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein PBP_sp32 PF07222.7 EIW67983.1 - 1 8.5 16.1 1.7 7.7 11.2 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Rtf2 PF04641.7 EIW67983.1 - 1.5 7.9 18.8 2.7 7.1 13.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger DHHW PF14286.1 EIW67983.1 - 2.4 7.3 9.4 4.1 6.6 6.5 1.3 1 0 0 1 1 1 0 DHHW protein CDC45 PF02724.9 EIW67983.1 - 3.2 5.6 18.0 5.9 4.7 12.5 1.3 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 EIW67983.1 - 4.4 7.3 22.3 11 6.0 15.5 1.6 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 EIW67983.1 - 7.4 6.3 22.7 0.69 9.7 12.4 1.6 2 0 0 2 2 1 0 Ryanodine Receptor TM 4-6 TP53IP5 PF15331.1 EIW67983.1 - 9.4 6.0 14.5 15 5.3 10.0 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SH3_1 PF00018.23 EIW67984.1 - 6.5e-19 67.0 0.2 4.7e-11 41.9 0.0 2.9 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EIW67984.1 - 3.7e-12 45.6 4.2 5.9e-05 22.5 0.0 3.9 4 0 0 4 4 4 2 Variant SH3 domain SH3_2 PF07653.12 EIW67984.1 - 9.4e-12 44.2 0.0 1.2e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EIW67984.1 - 1.4e-06 28.0 0.0 3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PX domain COPI_C PF06957.6 EIW67984.1 - 0.11 10.9 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Myb_Cef PF11831.3 EIW67985.1 - 1.2e-57 194.8 0.2 1.2e-57 194.8 0.1 3.8 3 1 1 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EIW67985.1 - 1.2e-19 70.1 9.3 4.3e-11 42.6 0.5 3.6 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW67985.1 - 3.9e-17 62.1 5.6 2.3e-12 46.8 2.9 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain DOT1 PF08123.8 EIW67986.1 - 1.9e-47 161.2 0.0 3.9e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EIW67986.1 - 0.00044 20.2 0.0 0.00079 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW67986.1 - 0.0021 18.5 0.0 0.0039 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GrpE PF01025.14 EIW67987.1 - 1.2e-43 148.5 0.1 2.2e-43 147.6 0.0 1.4 1 1 0 1 1 1 1 GrpE Tropomyosin_1 PF12718.2 EIW67987.1 - 0.044 13.6 1.4 0.062 13.1 1.0 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF1759 PF03564.10 EIW67987.1 - 0.06 13.1 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF4315 PF14193.1 EIW67987.1 - 0.095 12.6 1.6 1.3 8.9 0.9 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4315) Paralemmin PF03285.10 EIW67987.1 - 0.1 12.0 0.8 0.11 11.9 0.5 1.1 1 0 0 1 1 1 0 Paralemmin Oxysterol_BP PF01237.13 EIW67987.1 - 5.7 5.3 6.4 15 3.9 0.0 2.7 1 1 1 3 3 3 0 Oxysterol-binding protein Peptidase_C54 PF03416.14 EIW67990.1 - 5.8e-88 294.6 0.0 5.2e-87 291.5 0.0 2.0 1 1 0 1 1 1 1 Peptidase family C54 Glyco_hydro_cc PF11790.3 EIW67991.1 - 8.9e-55 185.7 0.5 1.1e-54 185.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.3 EIW67992.1 - 4.7e-40 137.5 0.0 6.3e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.3 EIW67993.1 - 6.4e-45 153.4 0.2 7.7e-45 153.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PAN_1 PF00024.21 EIW67995.1 - 0.0011 18.6 0.1 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EIW67996.1 - 0.00058 19.5 0.7 0.00058 19.5 0.5 2.0 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.7 EIW67996.1 - 0.0013 18.3 2.1 0.0013 18.3 1.5 1.6 1 1 1 2 2 2 1 PAN-like domain PAN_1 PF00024.21 EIW67996.1 - 0.0013 18.4 0.2 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 PAN domain Myb_DNA-binding PF00249.26 EIW67997.1 - 0.002 18.1 0.8 0.0041 17.1 0.6 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW67997.1 - 0.015 15.3 0.5 0.026 14.5 0.3 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW67998.1 - 0.018 15.1 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIW67998.1 - 0.02 14.9 1.3 0.022 14.8 0.1 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain PHD PF00628.24 EIW67999.1 - 9.4e-10 38.0 6.4 1.6e-09 37.3 4.5 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EIW67999.1 - 9.1e-07 29.1 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.1 EIW67999.1 - 0.076 12.3 0.7 0.14 11.4 0.5 1.4 1 0 0 1 1 1 0 PHD-finger Cyclin PF08613.6 EIW68000.1 - 1.3e-07 32.1 0.0 2.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin DUF788 PF05620.6 EIW68002.1 - 6.7e-36 123.6 0.0 7.9e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Mg_trans_NIPA PF05653.9 EIW68002.1 - 0.24 10.3 2.1 1.2 8.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium transporter NIPA FtsJ PF01728.14 EIW68003.1 - 4.2e-42 144.1 0.0 4.8e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase p450 PF00067.17 EIW68004.1 - 3.1e-35 121.5 0.0 4.9e-35 120.9 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 eIF3g PF12353.3 EIW68006.1 - 1.4e-39 134.8 0.7 2e-39 134.3 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EIW68006.1 - 7.3e-18 63.9 0.0 1.4e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW68006.1 - 1.5e-10 40.8 0.0 2.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW68006.1 - 1.1e-06 28.4 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GIT_SHD PF08518.6 EIW68007.1 - 4.5e-24 83.4 6.5 3.4e-12 45.5 1.1 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT BLOC1_2 PF10046.4 EIW68007.1 - 0.51 10.5 11.1 5.9 7.0 0.6 3.8 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.4 EIW68007.1 - 0.52 10.1 30.3 0.038 13.8 1.5 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EIW68007.1 - 0.8 9.2 24.6 0.49 9.9 8.0 3.2 3 0 0 3 3 3 0 IncA protein V_ATPase_I PF01496.14 EIW68007.1 - 0.84 7.4 7.5 2.1 6.1 4.8 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 EIW68007.1 - 0.94 7.8 10.1 0.13 10.6 4.0 1.7 2 0 0 2 2 2 0 AAA domain TBPIP PF07106.8 EIW68007.1 - 4.9 6.6 14.2 3.6 7.1 1.2 3.9 2 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 EIW68007.1 - 7.9 4.7 8.1 0.89 7.9 0.6 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF342) PALP PF00291.20 EIW68008.1 - 5.2e-75 252.5 0.5 7e-75 252.0 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EIW68008.1 - 6.6e-42 141.0 0.2 1.9e-25 88.2 0.0 3.4 3 0 0 3 3 3 3 C-terminal regulatory domain of Threonine dehydratase TPR_11 PF13414.1 EIW68009.1 - 7.2e-20 70.4 1.0 7.8e-07 28.6 0.0 5.6 3 2 1 5 5 5 3 TPR repeat TPR_16 PF13432.1 EIW68009.1 - 8.4e-15 54.9 4.1 0.0062 17.1 0.0 5.6 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIW68009.1 - 9.5e-15 53.7 7.7 0.019 15.5 0.0 7.7 5 2 3 8 8 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 EIW68009.1 - 1.3e-14 54.3 8.0 1.4e-05 25.2 0.0 5.4 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW68009.1 - 3.7e-14 51.4 0.0 0.054 13.4 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW68009.1 - 7.1e-13 47.6 0.8 0.091 13.0 0.1 6.5 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIW68009.1 - 1e-12 47.0 0.0 0.0042 16.6 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIW68009.1 - 2.2e-07 30.6 1.5 1 9.3 0.0 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW68009.1 - 4.6e-07 29.1 0.0 1.9 8.4 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EIW68009.1 - 0.00015 21.7 0.3 0.57 10.3 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIW68009.1 - 0.0002 20.9 0.4 17 5.5 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIW68009.1 - 0.0044 16.8 2.5 1.1 9.1 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 EIW68009.1 - 0.024 15.0 1.6 4.2 8.0 0.3 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat PPTA PF01239.17 EIW68009.1 - 0.065 12.6 0.0 1.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat TPR_20 PF14561.1 EIW68009.1 - 0.12 12.5 0.6 4.9 7.3 0.1 3.3 2 2 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.3 EIW68009.1 - 0.51 9.0 0.1 3.5 6.2 0.1 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 ChAPs PF09295.5 EIW68009.1 - 2 7.1 3.2 8.1 5.0 0.2 2.5 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2587 PF10759.4 EIW68011.1 - 0.034 13.5 0.1 0.08 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW68012.1 - 0.00023 20.9 1.3 0.00035 20.3 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW68012.1 - 0.059 13.0 0.5 0.2 11.3 0.4 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIW68012.1 - 0.12 12.1 1.3 0.25 11.0 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle SNO PF01174.14 EIW68013.1 - 2.4e-42 144.6 0.0 1.7e-34 119.0 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EIW68013.1 - 0.00032 20.3 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 EIW68013.1 - 0.0021 17.3 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DUF4154 PF13689.1 EIW68013.1 - 0.031 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) GATase PF00117.23 EIW68013.1 - 0.036 13.5 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase class-I UPF0147 PF03685.8 EIW68014.1 - 0.022 14.6 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) PAC2 PF09754.4 EIW68015.1 - 2.9e-14 53.4 0.0 6.2e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 PAC2 family tRNA-synt_1c PF00749.16 EIW68016.1 - 6.1e-93 310.9 0.0 9.5e-93 310.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Toxin_11 PF07473.6 EIW68016.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Spasmodic peptide gm9a MMR_HSR1 PF01926.18 EIW68017.1 - 8e-12 45.1 0.0 1.5e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 EIW68017.1 - 7.2e-05 21.7 0.0 0.00013 20.8 0.0 1.3 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EIW68017.1 - 0.00056 19.1 0.0 0.00082 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EIW68017.1 - 0.00086 18.6 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 EIW68017.1 - 0.0035 16.4 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EIW68017.1 - 0.034 14.6 0.0 0.069 13.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 EIW68017.1 - 0.037 13.8 0.2 0.12 12.1 0.0 1.9 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.1 EIW68017.1 - 0.041 13.8 0.1 0.041 13.8 0.0 1.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.1 EIW68017.1 - 0.041 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW68017.1 - 0.1 13.3 0.3 0.26 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Glyco_trans_2_3 PF13632.1 EIW68018.1 - 1.4e-08 34.6 0.1 1.4e-08 34.6 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW68018.1 - 0.00036 20.3 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PUA PF01472.15 EIW68019.1 - 3.3e-14 52.3 0.0 6.4e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 PUA domain SSP160 PF06933.6 EIW68020.1 - 2.3 6.1 9.1 2.8 5.8 6.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ORC2 PF04084.9 EIW68021.1 - 9.9e-75 251.3 0.0 1.7e-74 250.5 0.0 1.4 1 1 0 1 1 1 1 Origin recognition complex subunit 2 Med3 PF11593.3 EIW68021.1 - 0.11 11.7 3.2 0.22 10.7 2.2 1.6 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal RFC1 PF08519.7 EIW68022.1 - 2.4e-57 193.0 0.2 6.4e-55 185.1 0.0 2.6 3 0 0 3 3 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EIW68022.1 - 3.2e-15 56.0 0.0 8.6e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EIW68022.1 - 9.5e-12 45.2 0.0 3.4e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EIW68022.1 - 2.1e-07 30.0 0.1 5.8e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EIW68022.1 - 5.4e-05 23.3 0.0 0.00024 21.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIW68022.1 - 0.0002 21.2 0.0 0.00064 19.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW68022.1 - 0.00036 21.3 0.4 0.0013 19.4 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 EIW68022.1 - 0.00067 19.2 0.0 0.00067 19.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIW68022.1 - 0.00083 18.4 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIW68022.1 - 0.0013 18.7 0.2 0.0067 16.4 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EIW68022.1 - 0.0022 17.4 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain Zeta_toxin PF06414.7 EIW68022.1 - 0.0023 17.0 0.5 0.011 14.8 0.0 2.2 2 1 1 3 3 3 1 Zeta toxin AAA_33 PF13671.1 EIW68022.1 - 0.01 15.7 0.0 0.064 13.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EIW68022.1 - 0.02 15.1 1.3 0.057 13.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EIW68022.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EIW68022.1 - 0.03 14.0 0.0 0.88 9.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 EIW68022.1 - 0.044 13.5 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EIW68022.1 - 0.045 13.2 0.1 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Njmu-R1 PF15053.1 EIW68022.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family RNA_helicase PF00910.17 EIW68022.1 - 0.12 12.5 0.0 0.43 10.7 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EIW68022.1 - 0.12 12.3 1.3 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EIW68022.1 - 0.18 11.3 2.3 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain TRAPPC10 PF12584.3 EIW68024.1 - 5.4e-14 51.9 0.0 1.2e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 MmgE_PrpD PF03972.9 EIW68024.1 - 0.052 11.7 0.0 0.089 10.9 0.0 1.3 1 0 0 1 1 1 0 MmgE/PrpD family DUF1744 PF08490.7 EIW68025.1 - 1.1e-125 419.3 0.0 1.9e-125 418.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EIW68025.1 - 6.4e-66 222.4 0.1 1e-65 221.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EIW68025.1 - 2.2e-20 72.9 0.0 6.5e-20 71.3 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EIW68025.1 - 1.6e-07 31.0 0.1 5.3e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EIW68025.1 - 0.00019 21.2 0.0 0.00067 19.4 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily DIM PF08194.7 EIW68027.1 - 0.094 12.6 5.3 1.4 8.9 0.2 3.1 2 0 0 2 2 2 0 DIM protein TIP120 PF08623.5 EIW68029.1 - 3.2e-48 163.5 4.3 3.5e-47 160.1 0.1 3.7 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EIW68029.1 - 2.1e-13 49.0 14.7 1.9 8.7 0.0 12.0 14 0 0 14 14 14 5 HEAT repeat HEAT_2 PF13646.1 EIW68029.1 - 6.9e-11 42.2 22.9 0.035 14.3 0.0 9.4 6 4 3 9 9 9 6 HEAT repeats HEAT_EZ PF13513.1 EIW68029.1 - 3.4e-08 33.7 23.9 0.019 15.4 0.0 9.8 10 1 1 11 11 11 2 HEAT-like repeat Ribosomal_S16 PF00886.14 EIW68030.1 - 2e-25 88.2 0.1 3e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 SHS2_Rpb7-N PF03876.12 EIW68031.1 - 1.2e-06 28.5 0.1 2.9e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 TAF1D PF15333.1 EIW68031.1 - 0.02 14.6 1.9 0.02 14.6 1.3 1.5 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D DUF2693 PF10902.3 EIW68031.1 - 0.18 11.7 2.3 21 5.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2693) RNase_H2-Ydr279 PF09468.5 EIW68031.1 - 0.26 10.4 2.4 0.34 10.0 1.6 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Skp1_POZ PF03931.10 EIW68032.1 - 0.0005 20.1 0.1 0.021 14.9 0.0 2.2 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EIW68032.1 - 0.004 17.1 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain ATP-grasp_4 PF13535.1 EIW68032.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Peptidase_C36 PF05415.6 EIW68033.1 - 0.044 13.6 0.1 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase ABC_tran PF00005.22 EIW68034.1 - 4.8e-24 85.1 0.0 6.4e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EIW68034.1 - 6e-05 23.1 0.0 0.0001 22.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 EIW68034.1 - 9.8e-05 21.2 0.0 0.00013 20.7 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EIW68034.1 - 0.00013 21.9 0.0 0.00019 21.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EIW68034.1 - 0.00015 21.0 0.0 0.044 13.0 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW68034.1 - 0.00018 21.5 0.0 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EIW68034.1 - 0.0002 21.1 0.2 0.0013 18.6 0.1 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EIW68034.1 - 0.00029 20.5 0.0 0.00062 19.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 EIW68034.1 - 0.00049 20.4 0.0 0.0006 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EIW68034.1 - 0.00052 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain UPF0079 PF02367.12 EIW68034.1 - 0.00055 19.5 0.0 0.00095 18.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EIW68034.1 - 0.00067 20.4 0.0 0.0011 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW68034.1 - 0.00073 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EIW68034.1 - 0.00098 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EIW68034.1 - 0.0011 19.2 0.0 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EIW68034.1 - 0.0039 16.7 0.1 0.025 14.1 0.0 2.1 2 1 1 3 3 3 1 AAA domain DUF258 PF03193.11 EIW68034.1 - 0.0048 16.0 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIW68034.1 - 0.0057 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EIW68034.1 - 0.008 16.4 0.1 0.019 15.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.13 EIW68034.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 EIW68034.1 - 0.016 14.9 0.1 0.045 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EIW68034.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 EIW68034.1 - 0.024 14.0 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EIW68034.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain T2SE PF00437.15 EIW68034.1 - 0.033 13.1 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EIW68034.1 - 0.039 13.8 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIW68034.1 - 0.042 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EIW68034.1 - 0.043 13.3 0.1 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EIW68034.1 - 0.087 12.5 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.12 EIW68034.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_15 PF13175.1 EIW68034.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.20 EIW68034.1 - 0.12 11.8 0.1 0.37 10.2 0.1 1.6 1 1 1 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DEAD PF00270.24 EIW68034.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase cobW PF02492.14 EIW68034.1 - 0.15 11.4 0.1 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EIW68034.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase CS PF04969.11 EIW68036.1 - 0.00013 22.3 0.0 0.00024 21.5 0.0 1.4 1 0 0 1 1 1 1 CS domain Fork_head_N PF08430.7 EIW68036.1 - 6.4 7.1 19.5 10 6.5 13.5 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Aldose_epim PF01263.15 EIW68037.1 - 4.7e-37 127.7 0.0 5.4e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase bZIP_1 PF00170.16 EIW68038.1 - 2.6e-07 30.4 10.4 2.6e-07 30.4 7.2 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIW68038.1 - 3.4e-07 29.9 14.5 3.4e-07 29.9 10.1 2.2 3 0 0 3 3 3 1 Basic region leucine zipper Spc24 PF08286.6 EIW68038.1 - 0.068 12.8 8.1 0.65 9.7 0.9 2.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 ERM PF00769.14 EIW68038.1 - 0.19 11.2 11.8 0.25 10.8 7.9 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CCDC155 PF14662.1 EIW68038.1 - 0.49 9.9 12.0 0.051 13.1 3.7 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 EIW68038.1 - 1.6 8.5 15.5 0.27 11.0 4.1 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NYD-SP28_assoc PF14775.1 EIW68038.1 - 1.8 8.3 4.8 0.99 9.1 1.3 2.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain GBP_C PF02841.9 EIW68038.1 - 1.8 7.6 7.7 4.3 6.4 5.4 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain bZIP_Maf PF03131.12 EIW68038.1 - 4.4 7.6 17.8 0.14 12.4 7.5 2.1 3 0 0 3 3 3 0 bZIP Maf transcription factor 6PGD PF00393.14 EIW68039.1 - 1.4e-128 428.1 0.0 1.7e-128 427.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EIW68039.1 - 2.8e-51 173.5 0.0 4.1e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIW68039.1 - 0.024 15.0 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EIW68039.1 - 0.084 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EIW68039.1 - 0.093 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DNA_pol3_delta PF06144.8 EIW68040.1 - 0.05 13.1 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit BTB PF00651.26 EIW68041.1 - 3.7e-05 23.6 0.1 0.00013 21.9 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIW68042.1 - 0.00013 21.8 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MetRS-N PF09635.5 EIW68042.1 - 0.093 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 MetRS-N binding domain SNF2_N PF00176.18 EIW68043.1 - 1.7e-20 73.0 0.0 2.3e-19 69.3 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.12 EIW68043.1 - 1.5e-17 63.7 1.2 3.4e-17 62.5 0.0 2.2 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase Chromo PF00385.19 EIW68043.1 - 6.4e-10 38.5 0.2 6.4e-10 38.5 0.1 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIW68043.1 - 0.023 14.3 0.4 0.066 12.9 0.3 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Synaptobrevin PF00957.16 EIW68044.1 - 9.9e-15 53.9 0.6 1.5e-14 53.3 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EIW68044.1 - 2e-07 30.4 0.0 3.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain muHD PF10291.4 EIW68045.1 - 4.6e-35 121.0 0.0 9.1e-33 113.5 0.0 2.3 2 0 0 2 2 2 2 Muniscin C-terminal mu homology domain FCH PF00611.18 EIW68045.1 - 8.5e-08 32.2 1.4 1.5e-07 31.5 0.1 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Radical_SAM PF04055.16 EIW68046.1 - 3.4e-16 59.8 0.1 8.7e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EIW68046.1 - 2.6e-12 46.5 0.1 8.9e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIW68046.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2587 PF10759.4 EIW68047.1 - 0.019 14.3 0.1 0.054 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Dysbindin PF04440.11 EIW68047.1 - 0.65 9.7 6.8 0.17 11.6 2.2 1.9 2 0 0 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) zf-CCHC PF00098.18 EIW68048.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW68048.1 - 0.27 11.5 9.2 0.069 13.3 4.2 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW68048.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.18 EIW68049.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW68049.1 - 0.27 11.5 9.2 0.069 13.3 4.2 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW68049.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) MULE PF10551.4 EIW68050.1 - 1e-06 28.8 0.8 0.00015 21.8 0.1 3.2 2 1 0 2 2 2 1 MULE transposase domain NHR2 PF08788.6 EIW68050.1 - 0.2 11.1 4.5 0.11 11.9 0.6 2.4 2 0 0 2 2 2 0 NHR2 domain like DUF943 PF06092.7 EIW68052.1 - 0.035 13.4 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) Glyco_transf_49 PF13896.1 EIW68053.1 - 0.015 14.4 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan PspB PF06667.7 EIW68053.1 - 0.051 13.5 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Phage shock protein B Med25 PF11232.3 EIW68054.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 ERCC4 PF02732.10 EIW68055.1 - 0.0085 15.8 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain adh_short PF00106.20 EIW68056.1 - 4.3e-25 88.5 0.0 6.5e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW68056.1 - 2.6e-11 43.7 0.0 3.6e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW68056.1 - 2e-07 30.8 0.1 3.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW68056.1 - 0.00055 19.4 0.0 0.00091 18.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW68056.1 - 0.058 13.3 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding DUF1769 PF08588.5 EIW68057.1 - 1.5e-21 76.0 0.1 4.7e-21 74.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) DNA_pol_B_thumb PF14791.1 EIW68058.1 - 2.3e-16 59.2 0.0 5.1e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EIW68058.1 - 3.6e-12 46.3 0.0 8e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EIW68058.1 - 2.7e-09 37.0 0.0 1e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EIW68058.1 - 1.4e-05 24.5 0.0 3.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda WD40 PF00400.27 EIW68059.1 - 6.8e-36 120.8 10.2 9.6e-10 37.9 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW68059.1 - 0.0025 17.3 3.5 0.12 11.7 2.3 2.6 1 1 1 2 2 2 2 PQQ-like domain PhyH PF05721.8 EIW68060.1 - 2.1e-07 31.1 0.1 3.8e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EIW68060.1 - 0.0058 15.1 0.1 0.1 11.0 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 EIW68060.1 - 0.029 14.6 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Abhydrolase_6 PF12697.2 EIW68061.1 - 6.8e-22 78.4 0.0 8e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW68061.1 - 1.7e-17 63.5 0.0 3.6e-17 62.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW68061.1 - 3.5e-15 55.6 0.0 1.9e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EIW68061.1 - 4.3e-06 26.3 0.0 0.014 14.8 0.0 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EIW68061.1 - 6.1e-05 22.6 0.0 0.00045 19.8 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EIW68061.1 - 0.02 14.2 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Ferritin_2 PF13668.1 EIW68062.1 - 0.0064 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Aminotran_1_2 PF00155.16 EIW68063.1 - 1.1e-29 103.5 0.0 9.8e-26 90.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Iso_dh PF00180.15 EIW68064.1 - 8.3e-128 426.1 0.0 9.7e-128 425.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Actin PF00022.14 EIW68065.1 - 9.5e-67 225.1 0.0 1.2e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Actin FA_hydroxylase PF04116.8 EIW68066.1 - 7.4e-17 61.7 25.8 2e-16 60.3 15.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Selenoprotein_S PF06936.6 EIW68066.1 - 0.085 12.3 1.8 1.5 8.3 0.2 2.3 2 0 0 2 2 2 0 Selenoprotein S (SelS) DUF1640 PF07798.6 EIW68067.1 - 1.8e-15 57.4 0.4 2.1e-15 57.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1678 PF07913.6 EIW68067.1 - 0.012 15.1 0.4 0.017 14.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) IncA PF04156.9 EIW68067.1 - 0.047 13.2 0.1 0.059 12.9 0.1 1.1 1 0 0 1 1 1 0 IncA protein Apolipoprotein PF01442.13 EIW68067.1 - 0.098 12.1 1.7 0.12 11.8 1.2 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DNA_photolyase PF00875.13 EIW68067.1 - 0.13 11.9 0.1 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA photolyase SSFA2_C PF14723.1 EIW68067.1 - 0.16 11.6 1.3 0.26 11.0 0.7 1.4 1 1 0 1 1 1 0 Sperm-specific antigen 2 C-terminus AMP-binding PF00501.23 EIW68068.1 - 1.3e-82 277.4 0.0 1.6e-82 277.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW68068.1 - 2.3e-10 41.2 0.2 7e-10 39.7 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Prefoldin PF02996.12 EIW68069.1 - 7.2e-26 90.1 0.8 8.6e-26 89.9 0.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit End3 PF12761.2 EIW68069.1 - 0.034 13.7 0.2 0.054 13.1 0.1 1.4 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Ilar_coat PF01787.11 EIW68069.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 2 0 0 2 2 2 0 Ilarvirus coat protein Rootletin PF15035.1 EIW68069.1 - 0.098 12.6 1.0 0.12 12.3 0.7 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF2040 PF09745.4 EIW68071.1 - 1.2e-37 128.5 19.5 1.2e-37 128.5 13.5 2.9 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) ATP_bind_4 PF01902.12 EIW68072.1 - 1.7e-34 119.1 0.0 8.4e-27 93.9 0.0 2.4 1 1 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 EIW68072.1 - 9e-11 41.5 0.0 0.00043 20.0 0.0 2.8 3 0 0 3 3 3 2 Endoribonuclease L-PSP CHCH PF06747.8 EIW68073.1 - 4.7e-05 23.1 2.5 4.7e-05 23.1 1.7 2.3 2 1 0 2 2 2 1 CHCH domain Pet191_N PF10203.4 EIW68073.1 - 0.11 12.5 10.5 0.2 11.7 4.5 2.6 1 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EIW68073.1 - 0.48 10.4 10.4 0.1 12.6 1.9 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EIW68073.1 - 0.61 9.9 11.7 0.9 9.3 2.8 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_M24 PF00557.19 EIW68074.1 - 2.6e-23 82.6 0.0 3.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Fungal_trans PF04082.13 EIW68075.1 - 1.4e-13 50.3 0.1 1.4e-12 47.0 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW68075.1 - 3.5e-08 33.2 4.1 6.7e-08 32.3 2.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 EIW68076.1 - 5.3e-18 65.3 0.0 6.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW68076.1 - 8.4e-11 41.0 0.0 1.1e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIW68076.1 - 3e-05 23.9 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EIW68076.1 - 0.00022 20.2 0.0 0.16 10.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EIW68076.1 - 0.006 15.4 0.0 0.0099 14.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EIW68076.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIW68076.1 - 0.085 11.7 0.0 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Transaldolase PF00923.14 EIW68077.1 - 1.2e-34 119.7 0.0 1.4e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Transaldolase PRK PF00485.13 EIW68078.1 - 6e-14 52.0 0.1 1.3e-12 47.7 0.1 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EIW68078.1 - 3.9e-10 40.1 0.2 4.9e-09 36.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW68078.1 - 5.9e-06 27.1 4.0 7.3e-05 23.5 2.8 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW68078.1 - 0.0012 18.7 0.1 0.21 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW68078.1 - 0.0015 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EIW68078.1 - 0.0067 15.5 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 EIW68078.1 - 0.0088 15.9 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW68078.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EIW68078.1 - 0.038 13.3 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIW68078.1 - 0.044 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain GvpD PF07088.6 EIW68078.1 - 0.057 11.7 0.0 0.084 11.1 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA PF00004.24 EIW68078.1 - 0.068 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EIW68078.1 - 0.087 11.4 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein UPF0016 PF01169.14 EIW68079.1 - 1.3e-38 131.0 24.1 4.3e-20 71.6 6.6 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF4131 PF13567.1 EIW68079.1 - 0.0053 16.1 0.2 0.62 9.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) ApoO PF09769.4 EIW68080.1 - 9.6e-30 103.3 0.0 1.4e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein O PDZ_2 PF13180.1 EIW68081.1 - 9.3e-09 35.0 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 EIW68081.1 - 1.8e-05 24.7 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 EIW68081.1 - 0.081 13.1 0.0 0.29 11.3 0.0 2.0 1 1 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) MSA-2c PF12238.3 EIW68081.1 - 0.089 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Glyco_transf_90 PF05686.7 EIW68082.1 - 1.4e-18 66.8 2.7 3.3e-18 65.5 1.9 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 90 UAA PF08449.6 EIW68083.1 - 2.9e-70 236.5 5.1 3.4e-70 236.3 3.5 1.0 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EIW68083.1 - 1.2e-09 38.3 18.4 2.4e-07 30.9 2.8 3.0 3 0 0 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 EIW68083.1 - 1.9e-09 37.6 24.7 5.5e-07 29.6 6.6 3.6 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 EIW68083.1 - 3.4e-07 30.0 19.2 6e-05 22.7 5.6 3.2 2 2 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EIW68083.1 - 3.3e-05 23.1 2.2 0.069 12.2 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter DUF914 PF06027.7 EIW68083.1 - 0.0015 17.4 2.6 0.063 12.1 0.2 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) Multi_Drug_Res PF00893.14 EIW68083.1 - 0.081 13.4 7.9 11 6.5 0.0 4.1 3 1 0 4 4 4 0 Small Multidrug Resistance protein UPF0546 PF10639.4 EIW68083.1 - 0.24 11.2 4.2 1.5 8.6 0.2 2.9 2 1 0 3 3 3 0 Uncharacterised protein family UPF0546 GCR1_C PF12550.3 EIW68085.1 - 1.8e-16 59.7 1.2 2.3e-16 59.4 0.8 1.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF1073 PF06381.6 EIW68085.1 - 0.12 10.8 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) DUF3716 PF12511.3 EIW68086.1 - 0.1 12.2 5.7 0.18 11.4 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) PC-Esterase PF13839.1 EIW68087.1 - 6.1e-09 36.0 0.1 2.1e-08 34.3 0.1 1.8 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Hydrolase_3 PF08282.7 EIW68087.1 - 0.1 12.1 0.3 0.17 11.4 0.2 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF992 PF06186.6 EIW68087.1 - 0.15 11.3 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF992) DUF1325 PF07039.6 EIW68088.1 - 2.1e-30 105.0 0.0 2.9e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain 2-oxoacid_dh PF00198.18 EIW68089.1 - 1.6e-42 145.3 0.0 4.4e-21 75.2 0.0 2.3 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIW68089.1 - 2e-19 68.9 0.1 5e-19 67.7 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EIW68089.1 - 4.8e-14 51.6 0.2 9e-14 50.8 0.1 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EIW68089.1 - 0.0015 18.1 0.0 0.096 12.3 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 EIW68089.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein CTP_transf_2 PF01467.21 EIW68090.1 - 5e-17 62.3 0.0 7.9e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase SapA PF02199.10 EIW68090.1 - 0.13 12.0 1.4 0.23 11.2 1.0 1.3 1 0 0 1 1 1 0 Saposin A-type domain PLDc_2 PF13091.1 EIW68091.1 - 2e-09 37.2 0.0 0.0007 19.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EIW68091.1 - 0.0066 16.2 1.5 1.8 8.4 0.0 3.4 3 0 0 3 3 3 2 Phospholipase D Active site motif ELFV_dehydrog PF00208.16 EIW68092.1 - 6.6e-81 271.4 0.6 8.1e-81 271.1 0.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EIW68092.1 - 3e-47 159.4 0.0 5.7e-47 158.5 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EIW68092.1 - 0.061 13.5 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding AMP-binding PF00501.23 EIW68093.1 - 2.5e-93 312.7 0.1 3e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW68093.1 - 6.4e-20 71.8 0.3 3.4e-18 66.3 0.1 2.8 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ATP-synt_S1 PF05827.7 EIW68095.1 - 0.025 13.9 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) zf-CCHC PF00098.18 EIW68097.1 - 0.0029 17.4 1.9 0.0052 16.6 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW68097.1 - 0.07 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Nop14 PF04147.7 EIW68099.1 - 1.8 6.3 5.4 2.2 6.0 3.7 1.0 1 0 0 1 1 1 0 Nop14-like family TPR_MLP1_2 PF07926.7 EIW68101.1 - 0.023 14.4 0.3 0.049 13.3 0.2 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CDP-OH_P_transf PF01066.16 EIW68102.1 - 2.1e-10 40.7 2.6 2.1e-10 40.7 1.8 1.5 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Aminotran_1_2 PF00155.16 EIW68103.1 - 1.6e-61 208.3 0.0 1.9e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIW68103.1 - 5.4e-06 24.9 0.0 1.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EIW68103.1 - 0.011 14.4 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V WD40 PF00400.27 EIW68104.1 - 1.2e-84 275.4 23.8 1.3e-11 43.9 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EIW68104.1 - 2e-09 36.1 2.6 0.055 11.5 0.1 3.7 3 1 1 4 4 4 3 Nucleoporin Nup120/160 NLE PF08154.7 EIW68104.1 - 8.4e-07 28.9 0.1 1.7e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 EIW68104.1 - 6.5e-06 25.9 0.0 0.00023 20.9 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EIW68104.1 - 0.025 12.3 0.1 0.042 11.6 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Nucleoporin_N PF08801.6 EIW68104.1 - 0.028 13.1 5.1 2.1 6.9 0.2 3.4 2 2 1 3 3 3 0 Nup133 N terminal like DUF1513 PF07433.6 EIW68104.1 - 0.03 13.2 0.2 0.61 8.9 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) RRM_1 PF00076.17 EIW68105.1 - 5.2e-14 51.6 0.1 1.7e-05 24.3 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW68105.1 - 9.4e-13 47.9 0.0 3.6e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW68105.1 - 4.3e-07 29.6 0.0 9.8e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dak1 PF02733.12 EIW68106.1 - 1.1e-111 372.4 1.5 1.7e-111 371.9 1.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EIW68106.1 - 4.6e-37 127.3 0.2 9e-37 126.4 0.2 1.5 1 0 0 1 1 1 1 DAK2 domain TetR_C_5 PF08360.6 EIW68106.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 QacR-like protein, C-terminal region PQ-loop PF04193.9 EIW68107.1 - 7.5e-21 73.4 17.8 1.6e-11 43.5 1.5 3.6 3 0 0 3 3 3 2 PQ loop repeat CcmH PF03918.9 EIW68107.1 - 0.064 12.2 0.4 1.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Cytochrome C biogenesis protein WBP-1 PF11669.3 EIW68107.1 - 0.18 11.9 5.9 1.1 9.3 0.2 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 PV-1 PF06637.6 EIW68107.1 - 0.72 8.3 2.6 1.1 7.8 1.8 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Pex24p PF06398.6 EIW68107.1 - 2.1 7.0 5.5 0.21 10.3 0.7 1.6 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF3328 PF11807.3 EIW68107.1 - 2.3 7.8 8.9 3.5 7.2 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) zf-DHHC PF01529.15 EIW68107.1 - 4.4 6.6 6.8 20 4.5 4.7 2.3 1 1 0 1 1 1 0 DHHC palmitoyltransferase YjeF_N PF03853.10 EIW68108.1 - 2.3e-36 124.9 0.0 2.8e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus ANF_receptor PF01094.23 EIW68108.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.4 1 0 0 1 1 1 0 Receptor family ligand binding region ERG2_Sigma1R PF04622.7 EIW68109.1 - 1.7e-80 269.3 0.8 1.9e-80 269.1 0.6 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Acetyltransf_1 PF00583.19 EIW68110.1 - 4.8e-13 48.9 0.0 8e-13 48.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIW68110.1 - 8.6e-07 28.6 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIW68110.1 - 4.4e-06 26.7 0.0 5.3e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW68110.1 - 5.2e-05 23.3 0.0 8.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW68110.1 - 0.016 15.3 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW68110.1 - 0.031 14.1 0.1 0.046 13.5 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SpoIISB_antitox PF14185.1 EIW68110.1 - 0.065 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system Acetyltransf_4 PF13420.1 EIW68110.1 - 0.078 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Transaldolase PF00923.14 EIW68111.1 - 2.1e-18 66.4 0.0 2.9e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Transaldolase Acyl_transf_1 PF00698.16 EIW68111.1 - 0.097 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain DNA_pol_lambd_f PF10391.4 EIW68111.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda ADH_N PF08240.7 EIW68112.1 - 4.5e-22 77.8 4.4 2.6e-20 72.2 3.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW68112.1 - 4.2e-19 68.3 2.4 7.1e-19 67.6 0.4 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW68112.1 - 5.1e-06 27.4 0.2 0.00015 22.6 0.0 2.6 2 1 1 3 3 3 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EIW68112.1 - 0.00043 19.8 0.3 0.00082 18.9 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.16 EIW68113.1 - 5e-34 117.4 0.0 8.4e-29 100.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family FAD_binding_1 PF00667.15 EIW68114.1 - 7.1e-38 130.2 0.0 1.2e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EIW68114.1 - 5.4e-31 107.5 0.0 1.1e-30 106.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EIW68114.1 - 2.5e-16 60.1 0.0 5e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EIW68114.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain zf-CCHC PF00098.18 EIW68116.1 - 0.00014 21.5 2.0 0.00023 20.9 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIW68116.1 - 0.0068 15.8 0.1 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW68116.1 - 0.027 14.6 6.8 0.045 13.9 4.7 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain zf-CCHC_5 PF14787.1 EIW68116.1 - 7 6.2 8.5 0.77 9.2 2.2 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger SET PF00856.23 EIW68117.1 - 3.4e-26 92.4 0.3 1.6e-25 90.3 0.0 2.3 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.11 EIW68117.1 - 5.1e-16 58.8 5.3 5.1e-16 58.8 3.7 1.9 2 0 0 2 2 2 1 Pre-SET motif Tombus_movement PF05318.7 EIW68117.1 - 0.75 10.4 4.1 0.51 11.0 1.0 2.1 2 0 0 2 2 2 0 Tombusvirus movement protein TT_ORF2 PF02957.10 EIW68117.1 - 5.9 7.6 8.2 1.8 9.2 0.2 3.6 3 0 0 3 3 3 0 TT viral ORF2 GSH_synth_ATP PF03917.12 EIW68118.1 - 2.4e-83 279.7 0.0 7.9e-82 274.7 0.0 2.6 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EIW68118.1 - 3.9e-33 113.6 0.0 6.6e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase 2-Hacid_dh_C PF02826.14 EIW68119.1 - 5.6e-52 175.4 0.0 7.6e-52 175.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW68119.1 - 3.2e-18 65.4 0.0 4.1e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIW68119.1 - 0.00013 21.8 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIW68119.1 - 0.0091 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Mannosyl_trans3 PF11051.3 EIW68120.1 - 8.7e-06 25.2 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative WD40 PF00400.27 EIW68121.1 - 6.6e-54 177.9 32.1 1.1e-10 40.9 0.8 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EIW68121.1 - 0.0036 16.7 2.9 0.077 12.5 0.0 3.9 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Semialdhyde_dhC PF02774.13 EIW68122.1 - 4.6e-36 124.3 0.2 9.3e-34 116.8 0.1 2.1 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EIW68122.1 - 1.2e-26 93.3 0.0 2.9e-26 92.1 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EIW68122.1 - 0.006 16.4 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.15 EIW68122.1 - 0.018 14.4 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain adh_short PF00106.20 EIW68123.1 - 1.1e-12 48.1 0.3 2.9e-11 43.5 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW68123.1 - 8.2e-07 29.0 0.1 9e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW68123.1 - 0.00014 21.5 0.0 0.00031 20.4 0.0 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIW68123.1 - 0.032 13.1 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SURF6 PF04935.7 EIW68124.1 - 1.3e-31 109.5 15.2 1.3e-31 109.5 10.5 3.1 3 0 0 3 3 3 2 Surfeit locus protein 6 RRP14 PF15459.1 EIW68124.1 - 3.6e-16 58.9 1.7 3.6e-16 58.9 1.2 4.5 3 1 1 4 4 4 1 60S ribosome biogenesis protein Rrp14 API5 PF05918.6 EIW68124.1 - 3.6 5.9 16.4 0.098 11.1 5.3 2.0 2 1 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) BTB PF00651.26 EIW68126.1 - 0.049 13.6 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Kdo PF06293.9 EIW68128.1 - 0.0022 17.1 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HCO3_cotransp PF00955.16 EIW68131.1 - 2.8e-54 184.6 11.9 2.4e-30 105.6 2.8 3.0 2 1 1 3 3 3 3 HCO3- transporter family Mito_carr PF00153.22 EIW68132.1 - 3.3e-51 170.9 5.3 9.7e-19 66.8 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1996 PF09362.5 EIW68134.1 - 1.2e-49 169.1 0.3 8.6e-49 166.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) GMAP PF06540.6 EIW68135.1 - 0.07 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Galanin message associated peptide (GMAP) Kdo PF06293.9 EIW68135.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kdo PF06293.9 EIW68136.1 - 6.4e-05 22.1 0.1 8.1e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4219 PF13961.1 EIW68136.1 - 0.1 12.0 0.9 11 5.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Kdo PF06293.9 EIW68138.1 - 0.0002 20.4 0.0 0.00053 19.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cyt-b5 PF00173.23 EIW68140.1 - 3.9e-19 68.2 0.0 7e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EIW68140.1 - 2.9e-08 34.0 18.8 2.9e-08 34.0 13.1 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PMI_typeI PF01238.16 EIW68141.1 - 1.5e-105 353.2 0.0 1.9e-105 352.9 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EIW68141.1 - 0.013 14.9 0.0 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Cupin domain HD_assoc PF13286.1 EIW68141.1 - 0.031 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphohydrolase-associated domain Hat1_N PF10394.4 EIW68142.1 - 2.1e-42 144.9 0.0 3.3e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 EIW68142.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW68142.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.13 EIW68142.1 - 0.022 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family F-box-like PF12937.2 EIW68144.1 - 1.2e-06 28.1 0.8 2.2e-06 27.2 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW68144.1 - 0.0039 16.7 0.7 0.0039 16.7 0.5 1.8 2 0 0 2 2 2 1 F-box domain C2 PF00168.25 EIW68145.1 - 2.7e-08 33.5 0.0 6.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain COesterase PF00135.23 EIW68146.1 - 1.5e-63 215.3 0.0 2.1e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW68146.1 - 5.5e-07 29.3 0.1 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pro_isomerase PF00160.16 EIW68147.1 - 3e-47 160.6 0.0 7.5e-47 159.4 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EIW68147.1 - 0.12 11.5 4.8 0.63 9.1 0.0 3.5 4 0 0 4 4 4 0 Rtf2 RING-finger DUF2370 PF10176.4 EIW68148.1 - 1.1e-72 244.2 0.0 2e-72 243.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Polysacc_deac_1 PF01522.16 EIW68149.1 - 1e-08 34.8 0.0 4.4e-08 32.7 0.0 1.9 1 1 1 2 2 2 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.16 EIW68150.1 - 2.2e-05 24.1 0.0 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Mem_trans PF03547.13 EIW68151.1 - 5.9e-48 163.0 0.0 4.7e-47 160.1 0.0 2.2 1 1 0 1 1 1 1 Membrane transport protein DUF373 PF04123.8 EIW68151.1 - 0.99 8.3 4.8 1.3 8.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF373) NAD_binding_8 PF13450.1 EIW68152.1 - 1.4e-10 41.0 0.6 2.1e-09 37.2 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW68152.1 - 1.4e-05 25.1 0.0 0.00029 20.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW68152.1 - 7.6e-05 21.7 0.0 0.00028 19.8 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW68152.1 - 0.00036 20.6 0.1 0.00082 19.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW68152.1 - 0.00038 19.0 0.6 0.0017 16.9 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EIW68152.1 - 0.00063 18.7 0.2 0.0012 17.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIW68152.1 - 0.00063 20.0 0.1 1.3 9.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIW68152.1 - 0.0063 15.4 0.1 0.0098 14.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EIW68152.1 - 0.014 15.1 0.0 0.072 12.8 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EIW68152.1 - 0.017 14.1 0.0 0.041 12.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EIW68152.1 - 0.026 13.6 0.1 0.19 10.7 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase LUC7 PF03194.10 EIW68152.1 - 0.061 12.8 0.0 0.085 12.3 0.0 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Methyltransf_31 PF13847.1 EIW68153.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-bind_4 PF13837.1 EIW68154.1 - 0.0014 18.7 0.2 0.0042 17.1 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Mating_C PF12737.2 EIW68154.1 - 2.9 6.6 23.1 0.032 13.1 4.8 2.7 3 0 0 3 3 3 0 C-terminal domain of homeodomain 1 Nop PF01798.13 EIW68155.1 - 6.2e-61 204.0 0.0 1.4e-60 202.9 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EIW68155.1 - 3.6e-25 87.5 0.0 9e-25 86.2 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EIW68155.1 - 4.6e-22 77.9 0.3 2.4e-21 75.6 0.2 2.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain HHH_2 PF12826.2 EIW68155.1 - 0.06 13.2 0.5 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Ribonuc_red_lgC PF02867.10 EIW68156.1 - 5e-213 708.5 0.0 6.5e-213 708.1 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EIW68156.1 - 3.5e-25 87.5 0.2 1.1e-24 86.0 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EIW68156.1 - 7.4e-14 51.9 0.1 7.4e-13 48.7 0.0 2.5 2 0 0 2 2 2 1 ATP cone domain HEAT PF02985.17 EIW68157.1 - 4.8e-15 54.2 0.0 0.018 15.1 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EIW68157.1 - 1.9e-10 40.8 0.0 0.00016 21.8 0.0 4.5 2 2 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EIW68157.1 - 1.1e-07 32.1 0.3 0.056 13.9 0.0 6.7 7 1 1 8 8 7 1 HEAT-like repeat CLASP_N PF12348.3 EIW68157.1 - 1.7e-05 24.3 0.0 0.00014 21.3 0.0 2.5 2 1 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 EIW68157.1 - 4.7e-05 23.7 0.0 0.93 9.9 0.0 3.7 2 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region UME PF08064.8 EIW68157.1 - 0.0023 17.8 0.1 0.0094 15.8 0.0 2.0 2 0 0 2 2 2 1 UME (NUC010) domain DUF2435 PF10363.4 EIW68157.1 - 0.0044 16.8 0.0 0.12 12.3 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) ParcG PF10274.4 EIW68157.1 - 0.005 16.7 0.0 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 Parkin co-regulated protein Adaptin_N PF01602.15 EIW68157.1 - 0.033 12.5 0.1 36 2.4 0.0 1.9 1 1 0 1 1 1 0 Adaptin N terminal region DUF1206 PF06724.6 EIW68157.1 - 0.061 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Cnd1 PF12717.2 EIW68157.1 - 0.13 12.0 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 APS_kinase PF01583.15 EIW68158.1 - 4.7e-67 224.5 0.0 5.6e-67 224.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 EIW68158.1 - 7.3e-06 26.8 0.0 1.1e-05 26.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW68158.1 - 8.2e-06 25.7 0.0 1.7e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW68158.1 - 0.00013 22.2 0.0 0.00043 20.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EIW68158.1 - 0.00082 18.6 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EIW68158.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW68158.1 - 0.032 14.2 0.2 0.066 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.13 EIW68158.1 - 0.08 11.9 0.0 0.16 11.0 0.0 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase CPT PF07931.7 EIW68158.1 - 0.095 12.3 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 EIW68158.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.13 EIW68158.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EIW68158.1 - 0.14 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter WH2 PF02205.15 EIW68159.1 - 9.8e-09 34.5 0.3 2.7e-07 29.9 0.1 2.7 2 0 0 2 2 2 1 WH2 motif Gly_transf_sug PF04488.10 EIW68160.1 - 1.4e-07 31.8 0.3 2.6e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Tic20 PF09685.5 EIW68160.1 - 0.00012 22.0 0.8 0.00012 22.0 0.6 2.0 2 0 0 2 2 2 1 Tic20-like protein TcdA_TcdB PF12919.2 EIW68160.1 - 0.00015 20.4 0.0 0.00021 19.9 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EIW68160.1 - 0.029 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DUF4131 PF13567.1 EIW68160.1 - 1.1 8.7 12.0 4 6.8 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DHO_dh PF01180.16 EIW68161.1 - 2.3e-87 292.6 0.0 2.7e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase BNR PF02012.15 EIW68162.1 - 6.4e-07 28.2 42.4 0.6 10.1 0.5 11.6 11 0 0 11 11 11 5 BNR/Asp-box repeat PSII_BNR PF14870.1 EIW68162.1 - 0.0014 17.6 3.4 0.28 10.1 0.0 4.6 5 1 0 5 5 5 1 Photosynthesis system II assembly factor YCF48 Fe_dep_repr_C PF02742.10 EIW68162.1 - 0.0091 15.6 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain CHB_HEX_C_1 PF13290.1 EIW68162.1 - 0.19 11.5 9.6 15 5.4 1.0 4.9 5 0 0 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain DFP PF04127.10 EIW68163.1 - 2.9e-18 66.1 0.0 9e-12 44.9 0.0 2.1 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein CDH PF02611.10 EIW68163.1 - 0.027 13.7 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase DUF2587 PF10759.4 EIW68164.1 - 0.053 12.9 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW68165.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW68165.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW68165.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) PCI PF01399.22 EIW68166.1 - 1.1e-09 38.5 0.0 5.6e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 PCI domain zf-RING_2 PF13639.1 EIW68167.1 - 2.1e-15 56.2 4.8 2.1e-15 56.2 3.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW68167.1 - 1.4e-07 31.3 5.6 1.4e-07 31.3 3.9 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIW68167.1 - 3.9e-07 30.0 2.0 3.9e-07 30.0 1.4 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIW68167.1 - 8.7e-07 28.5 2.5 8.7e-07 28.5 1.7 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW68167.1 - 2.5e-06 27.0 2.7 2.5e-06 27.0 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW68167.1 - 6e-06 25.8 3.4 6e-06 25.8 2.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW68167.1 - 0.00026 20.6 1.4 0.0012 18.4 1.0 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EIW68167.1 - 0.00029 20.6 3.8 0.00072 19.3 2.7 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 EIW68167.1 - 0.0016 18.4 2.4 0.0016 18.4 1.6 2.7 3 0 0 3 3 3 1 zinc-finger Vps39_2 PF10367.4 EIW68167.1 - 0.016 15.3 0.7 0.81 9.8 0.0 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Rad50_zn_hook PF04423.9 EIW68167.1 - 0.04 13.3 0.7 6.9 6.2 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.3 EIW68167.1 - 0.65 9.9 6.8 13 5.7 4.9 2.7 1 1 1 2 2 2 0 FANCL C-terminal domain zf-TFIIB PF13453.1 EIW68167.1 - 0.82 8.9 7.6 4.3 6.6 0.6 3.3 3 0 0 3 3 3 0 Transcription factor zinc-finger DZR PF12773.2 EIW68167.1 - 1.6 8.6 6.9 2.8 7.8 0.1 2.8 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.24 EIW68167.1 - 3.4 7.4 12.4 0.22 11.2 2.3 2.6 3 0 0 3 3 2 0 PHD-finger Zn-ribbon_8 PF09723.5 EIW68167.1 - 3.8 7.5 6.2 2.9 7.9 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain DUF1451 PF07295.6 EIW68167.1 - 5.5 6.7 4.6 1 9.1 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) RINGv PF12906.2 EIW68167.1 - 8.3 6.5 9.0 1.8 8.6 1.3 2.4 2 1 0 2 2 2 0 RING-variant domain Prok-RING_1 PF14446.1 EIW68167.1 - 8.6 6.1 14.5 2.4 7.9 3.9 3.1 2 2 1 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EIW68167.1 - 9.7 5.8 12.7 1.1 8.9 3.4 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF4434 PF14488.1 EIW68169.1 - 0.15 11.8 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Zip PF02535.17 EIW68171.1 - 1.4e-34 119.5 4.7 1.4e-34 119.5 3.2 1.5 2 0 0 2 2 2 1 ZIP Zinc transporter DctQ PF04290.7 EIW68171.1 - 0.64 9.7 9.2 4.4 7.0 0.4 2.7 2 2 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Mannosyl_trans3 PF11051.3 EIW68172.1 - 4.8e-41 140.9 0.0 1.7e-40 139.0 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative FIST PF08495.5 EIW68173.1 - 0.1 11.7 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 FIST N domain Cellulase PF00150.13 EIW68174.1 - 2.4e-12 46.6 2.5 2.4e-12 46.6 1.8 2.4 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF1459 PF07312.6 EIW68174.1 - 0.0065 16.3 2.5 0.29 11.0 0.6 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1459) Colicin_D PF11429.3 EIW68174.1 - 0.075 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Colicin D DUF1917 PF08939.5 EIW68175.1 - 6.6e-16 58.7 0.0 1.1e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) zf-RING_2 PF13639.1 EIW68176.1 - 5.2e-07 29.3 8.6 5.2e-07 29.3 5.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EIW68176.1 - 4.1e-05 23.6 3.2 0.00011 22.2 2.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EIW68176.1 - 0.00016 21.5 4.6 0.00036 20.4 3.2 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EIW68176.1 - 0.0067 16.2 2.3 0.014 15.2 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EIW68176.1 - 0.056 13.5 7.1 0.13 12.3 4.9 1.7 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EIW68176.1 - 0.61 9.8 4.3 0.24 11.1 1.1 1.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 EIW68176.1 - 1.4 8.6 13.9 0.2 11.3 6.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EIW68176.1 - 7.7 6.6 6.4 16 5.6 4.4 1.6 1 0 0 1 1 1 0 RING-like domain CBFD_NFYB_HMF PF00808.18 EIW68177.1 - 1.1e-26 92.6 0.1 1.3e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIW68177.1 - 9.8e-07 28.8 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EIW68177.1 - 0.027 14.2 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit UQ_con PF00179.21 EIW68178.1 - 1.3e-17 63.5 0.0 1.5e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.13 EIW68178.1 - 0.0024 16.9 2.4 0.0045 16.0 0.3 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RWD PF05773.17 EIW68178.1 - 0.0088 15.9 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_E PF14462.1 EIW68178.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family E Rubredoxin PF00301.15 EIW68178.1 - 0.017 15.0 0.3 0.047 13.5 0.1 1.8 2 0 0 2 2 2 0 Rubredoxin UFC1 PF08694.6 EIW68178.1 - 0.093 12.1 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 ENTH PF01417.15 EIW68179.1 - 4.5e-50 168.6 0.1 8.2e-50 167.8 0.1 1.4 1 0 0 1 1 1 1 ENTH domain UIM PF02809.15 EIW68179.1 - 0.0045 16.4 17.2 0.005 16.3 3.7 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif PAT1 PF09770.4 EIW68179.1 - 0.095 10.9 58.2 0.13 10.4 40.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pinin_SDK_memA PF04696.8 EIW68180.1 - 4e-10 39.4 7.0 4e-10 39.4 4.8 3.4 2 2 1 3 3 3 1 pinin/SDK/memA/ protein conserved region zf-ZPR1 PF03367.8 EIW68180.1 - 0.026 13.7 0.4 0.026 13.7 0.2 2.1 2 1 0 2 2 2 0 ZPR1 zinc-finger domain DUF3450 PF11932.3 EIW68180.1 - 0.73 9.0 6.9 1 8.5 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF3435 PF11917.3 EIW68180.1 - 1.4 7.5 13.2 0.037 12.7 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) DUF4200 PF13863.1 EIW68180.1 - 2.5 8.0 21.5 5 7.1 5.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TMPIT PF07851.8 EIW68180.1 - 5.1 6.0 6.6 1.5 7.8 0.3 2.1 2 0 0 2 2 2 0 TMPIT-like protein Cauli_AT PF03233.8 EIW68180.1 - 5.8 6.5 9.8 5.4 6.6 1.0 2.4 2 0 0 2 2 2 0 Aphid transmission protein Peptidase_M76 PF09768.4 EIW68181.1 - 4.4e-70 234.6 4.7 5.3e-70 234.3 3.2 1.1 1 0 0 1 1 1 1 Peptidase M76 family Lem_TRP PF08262.6 EIW68182.1 - 0.5 10.2 2.1 0.97 9.3 0.3 2.3 2 0 0 2 2 2 0 Leucophaea maderae tachykinin-related peptide BMF PF15185.1 EIW68183.1 - 0.095 11.9 3.1 0.13 11.4 2.1 1.1 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis API5 PF05918.6 EIW68183.1 - 0.55 8.6 4.2 0.69 8.3 2.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Metallophos PF00149.23 EIW68184.1 - 5.8e-43 146.6 1.2 7.2e-43 146.3 0.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1768 PF08719.6 EIW68185.1 - 5.8e-44 149.6 0.1 6.4e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PPTA PF01239.17 EIW68186.1 - 4.7e-27 92.1 16.2 4.4e-07 28.9 0.7 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_6 PF13174.1 EIW68186.1 - 1.1 9.9 3.7 3.1 8.4 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat XFP_N PF09364.5 EIW68187.1 - 5.8e-82 275.2 0.1 2.9e-80 269.6 0.1 2.7 1 1 1 2 2 2 2 XFP N-terminal domain XFP PF03894.10 EIW68187.1 - 4.8e-68 228.2 0.0 9.9e-68 227.2 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EIW68187.1 - 1.2e-56 191.3 0.0 1.8e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain DUF498 PF04430.9 EIW68187.1 - 0.0041 16.6 0.1 0.046 13.2 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF498/DUF598) Transketolase_C PF02780.15 EIW68187.1 - 0.013 15.4 0.2 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain ParA PF10609.4 EIW68188.1 - 1.5e-37 127.3 0.0 2.7e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIW68188.1 - 1.4e-14 53.9 0.0 1.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIW68188.1 - 8.9e-05 22.4 0.0 0.00037 20.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EIW68188.1 - 0.00013 21.1 1.5 0.002 17.2 0.2 2.5 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.1 EIW68188.1 - 0.00051 19.7 0.0 0.022 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIW68188.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 EIW68188.1 - 0.0015 17.9 0.1 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 YhjQ protein Fer4_NifH PF00142.13 EIW68188.1 - 0.0038 16.4 0.0 0.15 11.1 0.0 2.4 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 EIW68188.1 - 0.0043 16.7 0.2 1 9.1 0.0 2.7 2 1 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 EIW68188.1 - 0.021 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EIW68188.1 - 0.025 13.7 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MipZ PF09140.6 EIW68188.1 - 0.042 12.9 0.0 0.16 11.0 0.0 1.8 1 1 0 1 1 1 0 ATPase MipZ YjeF_N PF03853.10 EIW68188.1 - 0.1 12.2 0.0 5.8 6.4 0.0 2.4 3 0 0 3 3 3 0 YjeF-related protein N-terminus UPF0079 PF02367.12 EIW68188.1 - 0.11 12.0 0.1 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Paf1 PF03985.8 EIW68189.1 - 8.9e-38 130.1 0.8 1e-37 129.9 0.5 1.1 1 0 0 1 1 1 1 Paf1 PI3_PI4_kinase PF00454.22 EIW68190.1 - 2.7e-48 164.5 0.0 1e-47 162.6 0.0 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 EIW68190.1 - 1.2e-27 95.9 0.0 1.9e-26 92.0 0.0 3.2 2 1 0 2 2 2 1 UME (NUC010) domain FAT PF02259.18 EIW68190.1 - 2e-17 63.2 0.7 8e-17 61.2 0.5 2.1 1 0 0 1 1 1 1 FAT domain HEAT_2 PF13646.1 EIW68190.1 - 7e-05 23.0 9.4 0.32 11.2 0.1 6.0 5 1 1 6 6 6 2 HEAT repeats DUF3385 PF11865.3 EIW68190.1 - 7.6e-05 22.6 0.1 0.0088 15.9 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) HEAT PF02985.17 EIW68190.1 - 0.0028 17.6 4.1 27 5.2 0.1 5.4 5 0 0 5 5 5 0 HEAT repeat FATC PF02260.15 EIW68190.1 - 0.003 16.9 0.3 0.0072 15.7 0.2 1.6 1 0 0 1 1 1 1 FATC domain Steroid_dh PF02544.11 EIW68190.1 - 0.15 11.8 0.0 0.47 10.2 0.0 1.8 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Ribosomal_L6e PF01159.14 EIW68191.1 - 1.4e-38 131.3 0.1 2.4e-38 130.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 EIW68191.1 - 0.00056 19.7 0.1 0.00056 19.7 0.1 2.3 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain Methyltransf_16 PF10294.4 EIW68192.1 - 2.8e-19 69.2 0.0 3.9e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Metallophos PF00149.23 EIW68193.1 - 5.1e-39 133.7 0.5 6.3e-39 133.4 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW68193.1 - 0.0034 17.2 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ANTH PF07651.11 EIW68194.1 - 2.4e-74 249.5 2.9 5.8e-74 248.2 0.0 2.9 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EIW68194.1 - 3.5e-64 215.3 7.0 3.5e-64 215.3 4.9 4.9 5 3 2 7 7 7 1 I/LWEQ domain ENTH PF01417.15 EIW68194.1 - 3.5e-05 23.6 0.9 0.00013 21.7 0.0 2.6 3 0 0 3 3 3 1 ENTH domain UQ_con PF00179.21 EIW68195.1 - 2.2e-45 153.5 0.0 2.6e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW68195.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B AAA PF00004.24 EIW68196.1 - 1.2e-41 142.0 0.0 2.1e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW68196.1 - 2.7e-06 27.5 0.1 0.00056 20.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIW68196.1 - 7.6e-06 25.9 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EIW68196.1 - 3.4e-05 22.8 0.0 6.5e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EIW68196.1 - 0.00015 21.7 0.1 0.0015 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EIW68196.1 - 0.00029 20.5 0.2 0.0016 18.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EIW68196.1 - 0.0007 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EIW68196.1 - 0.0011 18.8 0.0 0.0041 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIW68196.1 - 0.003 17.1 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EIW68196.1 - 0.0056 15.8 0.1 0.15 11.1 0.0 2.5 1 1 1 2 2 2 1 KaiC AAA_19 PF13245.1 EIW68196.1 - 0.0066 16.1 0.3 0.015 15.0 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EIW68196.1 - 0.0068 17.2 0.2 0.018 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW68196.1 - 0.007 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EIW68196.1 - 0.011 15.7 0.2 0.078 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EIW68196.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EIW68196.1 - 0.013 14.9 0.4 0.76 9.1 0.1 2.4 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIW68196.1 - 0.02 15.2 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EIW68196.1 - 0.022 13.6 0.0 0.084 11.7 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 EIW68196.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 EIW68196.1 - 0.031 13.9 0.1 0.43 10.2 0.1 2.5 2 1 0 3 3 3 0 NACHT domain TIP49 PF06068.8 EIW68196.1 - 0.04 12.6 0.0 0.069 11.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Viral_helicase1 PF01443.13 EIW68196.1 - 0.073 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EIW68196.1 - 0.08 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Porin_OmpL1 PF11389.3 EIW68196.1 - 0.095 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 PhoH PF02562.11 EIW68196.1 - 0.11 11.6 0.1 0.38 9.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 EIW68196.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EIW68196.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EIW68196.1 - 0.13 11.8 0.1 0.35 10.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain VID27 PF08553.5 EIW68197.1 - 5.9e-278 924.3 3.7 3.1e-236 786.4 0.6 2.0 1 1 1 2 2 2 2 VID27 cytoplasmic protein Arf PF00025.16 EIW68198.1 - 2.3e-78 261.4 0.1 2.6e-78 261.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIW68198.1 - 1e-14 54.1 0.0 1.3e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EIW68198.1 - 6.8e-13 48.3 0.0 7.2e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EIW68198.1 - 1.4e-11 43.7 1.0 5.8e-09 35.1 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EIW68198.1 - 2.5e-11 43.1 0.0 3e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIW68198.1 - 3e-09 37.3 0.0 4.3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW68198.1 - 4.2e-06 26.7 0.0 5.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EIW68198.1 - 0.0088 15.1 0.4 0.019 14.0 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EIW68198.1 - 0.016 14.6 0.0 0.095 12.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EIW68198.1 - 0.037 13.8 0.1 0.14 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EIW68198.1 - 0.11 12.0 0.3 1.9 7.9 0.1 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF202 PF02656.10 EIW68199.1 - 4.5e-07 30.0 4.5 2.1e-06 27.8 3.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF2339 PF10101.4 EIW68199.1 - 0.0041 15.4 2.2 0.0053 15.1 1.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) EamA PF00892.15 EIW68199.1 - 0.18 11.8 2.1 0.33 11.0 0.3 2.0 2 0 0 2 2 2 0 EamA-like transporter family NTP_transferase PF00483.18 EIW68200.1 - 1.1e-28 100.1 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EIW68200.1 - 1.6e-08 33.6 2.8 2.8e-05 23.3 0.2 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EIW68200.1 - 1.1e-06 28.8 0.0 3.5e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.14 EIW68200.1 - 0.0077 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Hexapep_2 PF14602.1 EIW68200.1 - 0.1 12.1 0.9 10 5.7 0.1 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase SH3_9 PF14604.1 EIW68204.1 - 3.4e-15 55.3 0.0 6.7e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW68204.1 - 6e-14 51.1 0.2 1.1e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EIW68204.1 - 2e-13 50.4 0.0 3.8e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 EIW68204.1 - 4.3e-12 45.6 0.0 1e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIW68204.1 - 1.1e-10 41.5 0.0 3.6e-10 39.8 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 EIW68204.1 - 1.1e-09 37.6 0.1 2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 EIW68204.1 - 0.00016 21.8 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Ste50p-SAM PF09235.5 EIW68204.1 - 0.00055 19.9 0.0 0.003 17.5 0.0 2.0 2 0 0 2 2 2 1 Ste50p, sterile alpha motif PH_8 PF15409.1 EIW68204.1 - 0.0028 17.6 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF918 PF06033.6 EIW68204.1 - 0.3 10.6 0.0 0.57 9.7 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) RhoGAP PF00620.22 EIW68205.1 - 1.9e-39 134.6 0.0 2.8e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 EIW68205.1 - 0.0077 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RRM_1 PF00076.17 EIW68206.1 - 3.2e-10 39.4 0.0 5.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW68206.1 - 2.1e-09 37.2 0.0 3.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EIW68206.1 - 0.00068 20.0 0.2 0.00068 20.0 0.1 2.3 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EIW68206.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VPS9 PF02204.13 EIW68207.1 - 4.8e-31 106.8 0.1 1.9e-30 104.9 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EIW68207.1 - 1.7e-12 46.5 0.9 1.6e-11 43.4 0.1 2.5 2 0 0 2 2 2 1 CUE domain DMA PF03474.9 EIW68207.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif UBA PF00627.26 EIW68207.1 - 0.16 11.8 1.0 8.3 6.3 0.0 2.7 2 0 0 2 2 2 0 UBA/TS-N domain Epimerase PF01370.16 EIW68208.1 - 2.9e-42 144.7 0.0 4e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW68208.1 - 9.6e-12 44.3 0.0 1.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIW68208.1 - 1.3e-11 43.8 0.0 1.7e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW68208.1 - 3.2e-09 36.0 0.1 3.6e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein UXS1_N PF11803.3 EIW68208.1 - 2.1e-07 30.6 0.0 4.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucuronate decarboxylase N-terminal Polysacc_synt_2 PF02719.10 EIW68208.1 - 1.5e-06 27.2 0.2 0.0025 16.7 0.1 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIW68208.1 - 9.4e-06 25.7 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIW68208.1 - 0.092 12.6 0.2 0.22 11.4 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Vps52 PF04129.7 EIW68210.1 - 3.6e-53 180.8 0.0 1.2e-35 123.0 0.0 2.0 2 0 0 2 2 2 2 Vps52 / Sac2 family IncA PF04156.9 EIW68210.1 - 0.0098 15.5 1.4 0.019 14.5 0.2 2.0 2 0 0 2 2 2 1 IncA protein Sec3_C PF09763.4 EIW68210.1 - 0.042 11.9 0.0 0.18 9.9 0.0 1.9 1 1 0 1 1 1 0 Exocyst complex component Sec3 DegS PF05384.6 EIW68210.1 - 0.065 12.4 1.3 0.14 11.3 0.1 2.0 2 0 0 2 2 2 0 Sensor protein DegS Mating_N PF12731.2 EIW68210.1 - 4.1 7.3 7.3 0.27 11.1 0.2 2.5 3 0 0 3 3 3 0 Mating-type protein beta 1 ChAPs PF09295.5 EIW68211.1 - 7.2e-149 495.8 0.0 1.7e-148 494.6 0.0 1.6 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 EIW68211.1 - 2e-07 31.2 2.8 2.5e-05 24.5 0.3 3.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIW68211.1 - 3.1e-07 29.8 3.1 0.093 12.6 0.1 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW68211.1 - 9.7e-06 25.7 3.8 1 10.1 0.0 5.4 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIW68211.1 - 1.1e-05 24.9 3.5 0.014 15.0 0.0 3.5 3 0 0 3 3 3 1 TPR repeat Apc3 PF12895.2 EIW68211.1 - 0.00013 22.0 6.4 0.064 13.3 0.1 3.9 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIW68211.1 - 0.0013 19.3 2.0 4.7 8.0 0.0 3.8 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIW68211.1 - 0.0024 16.9 3.5 0.041 12.9 0.2 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW68211.1 - 0.0029 17.9 0.5 7.2 7.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIW68211.1 - 0.066 13.0 0.5 1.5 8.7 0.0 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIW68211.1 - 0.3 11.0 7.8 6.7 6.7 0.2 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Adap_comp_sub PF00928.16 EIW68212.1 - 4.4e-89 298.0 0.0 6.5e-89 297.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIW68212.1 - 4.4e-07 29.7 0.4 7.2e-07 29.0 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EIW68212.1 - 0.0071 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Rho_GDI PF02115.12 EIW68213.1 - 1.1e-53 181.6 0.0 1.2e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ras PF00071.17 EIW68214.1 - 1.8e-54 183.4 0.0 2.1e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW68214.1 - 7.4e-15 55.5 0.0 1.1e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW68214.1 - 5.4e-08 32.2 0.0 7.7e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIW68214.1 - 0.00024 20.3 0.0 0.00033 19.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EIW68214.1 - 0.0017 17.7 0.0 0.0079 15.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIW68214.1 - 0.042 12.9 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Glyco_transf_28 PF03033.15 EIW68215.1 - 3.3e-22 78.7 0.0 7.4e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EIW68215.1 - 6.3e-10 38.2 0.0 9.6e-10 37.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GRAM PF02893.15 EIW68215.1 - 0.0041 16.5 0.0 0.68 9.5 0.0 2.5 2 0 0 2 2 2 2 GRAM domain PH PF00169.24 EIW68215.1 - 0.0044 17.2 0.0 0.11 12.6 0.0 3.0 4 0 0 4 4 4 1 PH domain RTC PF01137.16 EIW68216.1 - 1.1e-59 200.9 0.0 1.4e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EIW68216.1 - 5.9e-30 103.3 0.0 9.2e-30 102.7 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RasGAP PF00616.14 EIW68217.1 - 5.6e-21 75.1 0.1 2.7e-19 69.6 0.0 3.0 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase G6PD_C PF02781.11 EIW68218.1 - 1.4e-121 404.8 0.0 1.9e-121 404.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EIW68218.1 - 1e-59 201.8 0.2 1.5e-59 201.2 0.2 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EIW68218.1 - 0.015 15.8 0.0 0.054 14.0 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NMO PF03060.10 EIW68219.1 - 5.1e-44 150.7 2.4 1.3e-42 146.1 1.7 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIW68219.1 - 1.1e-07 31.1 0.0 0.011 14.5 0.3 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain DUF1902 PF08972.6 EIW68219.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) DUF561 PF04481.7 EIW68219.1 - 0.045 12.6 0.1 0.25 10.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF561) CorA PF01544.13 EIW68220.1 - 9.5e-47 159.4 0.1 1.3e-46 158.9 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 EIW68220.1 - 0.011 15.5 0.4 0.023 14.5 0.2 1.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACT_4 PF13291.1 EIW68220.1 - 0.075 13.3 0.0 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 ACT domain A_thal_3526 PF09713.5 EIW68220.1 - 0.13 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Methyltransf_3 PF01596.12 EIW68221.1 - 3.5e-29 101.3 0.0 4.7e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIW68221.1 - 7.9e-12 45.9 0.0 1.2e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW68221.1 - 7e-06 26.5 0.0 1.2e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW68221.1 - 0.039 13.9 0.0 0.093 12.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EIW68221.1 - 0.093 12.2 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Sld5 PF05916.6 EIW68223.1 - 0.0011 19.1 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein WW PF00397.21 EIW68224.1 - 0.0017 18.1 7.3 0.0017 18.1 5.0 2.0 2 0 0 2 2 2 1 WW domain Glyco_hydro_71 PF03659.9 EIW68225.1 - 2.2e-103 345.7 6.1 3.7e-103 344.9 4.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.14 EIW68225.1 - 5.6e-35 119.1 48.9 1.5e-18 66.4 10.9 3.3 3 0 0 3 3 3 2 WSC domain RdRP PF05183.7 EIW68226.1 - 4.2e-123 412.0 0.0 6.5e-123 411.4 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase SLX9 PF15341.1 EIW68227.1 - 5.3e-09 36.5 3.1 8.6e-09 35.8 2.2 1.4 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 Ribonucleas_3_2 PF11469.3 EIW68227.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease III Serine_rich PF08824.5 EIW68231.1 - 0.072 12.7 0.5 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Serine rich protein interaction domain Asp_protease_2 PF13650.1 EIW68233.1 - 6.8e-06 26.5 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIW68233.1 - 3.5e-05 23.5 0.0 8.6e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIW68233.1 - 0.00021 21.1 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF294 PF03445.8 EIW68235.1 - 0.11 12.1 0.0 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Putative nucleotidyltransferase DUF294 GATA PF00320.22 EIW68237.1 - 1.7e-11 43.2 2.2 3.9e-11 42.0 1.5 1.6 1 0 0 1 1 1 1 GATA zinc finger FUSC_2 PF13515.1 EIW68238.1 - 9.6e-21 74.0 9.8 9.6e-21 74.0 6.8 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 EIW68238.1 - 7.4e-13 47.8 16.1 1.7e-11 43.3 5.3 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein family ALMT PF11744.3 EIW68238.1 - 5.5e-11 41.7 2.4 2.7e-07 29.5 0.9 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 EIW68238.1 - 6.5e-06 25.9 0.0 5.5e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC-like PF12805.2 EIW68238.1 - 0.14 11.0 0.0 0.14 11.0 0.0 2.7 3 0 0 3 3 3 0 FUSC-like inner membrane protein yccS THUMP PF02926.12 EIW68239.1 - 3e-08 33.6 0.9 8.5e-08 32.1 0.0 1.9 1 1 1 2 2 2 1 THUMP domain BBIP10 PF14777.1 EIW68239.1 - 2.1 7.7 7.0 0.093 12.1 0.7 1.9 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 SAPS PF04499.10 EIW68240.1 - 4.9e-118 394.7 0.0 2.1e-117 392.6 0.0 2.0 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein PHD PF00628.24 EIW68241.1 - 5e-10 38.9 5.7 1e-09 37.9 4.0 1.5 1 0 0 1 1 1 1 PHD-finger ESR1_C PF12743.2 EIW68241.1 - 0.18 11.3 4.1 5.6 6.5 1.8 2.7 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal PSII_Pbs27 PF13326.1 EIW68242.1 - 0.087 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Photosystem II Pbs27 PT PF04886.7 EIW68244.1 - 6.2 6.2 12.3 8.3 5.8 1.2 2.6 2 0 0 2 2 2 0 PT repeat DUF972 PF06156.8 EIW68245.1 - 0.025 14.9 0.2 0.03 14.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4559 PF15112.1 EIW68245.1 - 0.061 12.4 0.1 0.064 12.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) cwf21 PF08312.7 EIW68245.1 - 0.14 12.0 1.2 0.25 11.2 0.8 1.4 1 0 0 1 1 1 0 cwf21 domain IcmL PF11393.3 EIW68246.1 - 0.092 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Macrophage killing protein with similarity to conjugation protein Methyltransf_16 PF10294.4 EIW68247.1 - 2.7e-15 56.2 0.0 3.5e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 EIW68247.1 - 0.0032 16.6 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.8 EIW68247.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIW68247.1 - 0.067 13.7 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EIW68247.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 EIW68247.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family zf-C3HC4_3 PF13920.1 EIW68248.1 - 2.9e-10 39.6 12.5 4.7e-10 38.9 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3513 PF12026.3 EIW68248.1 - 0.68 9.4 4.7 1.2 8.6 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) zf-C3HC4_2 PF13923.1 EIW68248.1 - 0.79 9.8 14.6 1.4 8.9 10.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.20 EIW68250.1 - 9.4e-26 90.7 0.0 1.2e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW68250.1 - 7.9e-15 55.2 0.0 9.5e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW68250.1 - 9.7e-12 44.9 0.1 2.2e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EIW68250.1 - 0.016 14.3 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Response_reg PF00072.19 EIW68251.1 - 9.3e-20 70.7 0.0 1.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HSF_DNA-bind PF00447.12 EIW68251.1 - 1.2e-17 63.9 0.0 1.1e-16 60.8 0.0 2.5 2 1 0 2 2 2 1 HSF-type DNA-binding DUF3429 PF11911.3 EIW68252.1 - 3.9e-40 137.1 14.7 5.2e-40 136.6 10.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Transcrip_reg PF01709.15 EIW68254.1 - 1.6e-56 191.0 0.0 1.8e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator WD40 PF00400.27 EIW68255.1 - 2.8e-34 115.7 11.8 1.9e-08 33.8 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat AAA PF00004.24 EIW68257.1 - 6.6e-87 288.4 0.0 3e-43 147.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW68257.1 - 6.5e-13 48.6 0.2 5e-06 26.2 0.0 4.4 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW68257.1 - 2.5e-12 47.1 0.6 1.3e-05 25.3 0.1 3.5 2 2 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 EIW68257.1 - 1.4e-11 43.8 0.0 0.00031 19.8 0.0 3.8 4 1 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIW68257.1 - 3.6e-11 43.3 0.1 0.00024 21.2 0.0 4.8 3 2 1 4 4 3 2 AAA domain AAA_2 PF07724.9 EIW68257.1 - 3.1e-10 40.2 0.0 0.00068 19.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EIW68257.1 - 1.4e-09 38.7 0.2 6.6e-05 23.7 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EIW68257.1 - 9.7e-08 32.0 0.0 0.00011 22.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EIW68257.1 - 1.4e-07 30.8 0.0 0.002 17.2 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EIW68257.1 - 1.5e-07 30.4 0.0 0.002 16.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EIW68257.1 - 3e-07 30.0 2.9 0.25 10.7 0.1 4.3 2 2 1 3 3 3 3 AAA domain Mg_chelatase PF01078.16 EIW68257.1 - 3.1e-07 29.7 0.2 0.0055 15.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIW68257.1 - 7e-07 29.1 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIW68257.1 - 1.7e-06 27.6 2.5 0.00044 19.9 0.1 3.3 3 1 0 3 3 2 1 Part of AAA domain IstB_IS21 PF01695.12 EIW68257.1 - 2.7e-06 26.9 0.0 0.018 14.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 EIW68257.1 - 2.9e-06 27.3 0.0 0.01 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EIW68257.1 - 7.6e-06 25.6 0.1 0.14 11.7 0.0 3.9 4 0 0 4 4 3 1 NACHT domain RNA_helicase PF00910.17 EIW68257.1 - 1.2e-05 25.4 0.0 0.06 13.5 0.0 2.6 2 1 0 2 2 2 2 RNA helicase Sigma54_activ_2 PF14532.1 EIW68257.1 - 3.5e-05 23.8 0.0 0.025 14.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 EIW68257.1 - 0.00013 21.6 0.4 0.053 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIW68257.1 - 0.0002 21.1 0.0 0.063 12.9 0.0 3.3 2 2 2 4 4 4 1 Archaeal ATPase Sigma54_activat PF00158.21 EIW68257.1 - 0.00021 20.8 0.0 1.9 7.9 0.0 4.3 2 2 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 EIW68257.1 - 0.00034 20.9 0.0 0.014 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIW68257.1 - 0.00063 19.3 0.0 0.96 9.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EIW68257.1 - 0.00064 18.6 0.0 0.0076 15.1 0.0 2.0 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EIW68257.1 - 0.00068 19.2 0.0 0.048 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EIW68257.1 - 0.0014 17.4 0.0 0.019 13.6 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 EIW68257.1 - 0.0027 16.6 0.0 0.4 9.5 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) KaiC PF06745.8 EIW68257.1 - 0.0043 16.2 0.0 2.1 7.4 0.0 2.9 2 1 1 3 3 3 1 KaiC UPF0079 PF02367.12 EIW68257.1 - 0.0094 15.5 0.0 0.54 9.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EIW68257.1 - 0.025 14.8 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 EIW68257.1 - 0.078 11.8 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.11 EIW68257.1 - 0.098 11.8 0.5 0.96 8.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 EIW68257.1 - 0.13 11.8 0.1 0.83 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 EIW68257.1 - 0.13 11.1 0.0 0.34 9.7 0.0 1.6 2 0 0 2 2 1 0 Mitochondrial ribosomal death-associated protein 3 IPT PF01745.11 EIW68257.1 - 0.21 10.7 0.2 8.5 5.4 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_23 PF13476.1 EIW68257.1 - 0.27 11.5 0.0 0.61 10.3 0.0 1.5 2 0 0 2 2 1 0 AAA domain YTH PF04146.10 EIW68258.1 - 1.7e-44 150.8 0.2 2e-44 150.6 0.1 1.0 1 0 0 1 1 1 1 YT521-B-like domain CALCOCO1 PF07888.6 EIW68258.1 - 0.12 10.6 0.1 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like zf-MYND PF01753.13 EIW68259.1 - 1.7e-06 27.7 14.3 3.9e-06 26.6 9.9 1.6 1 1 0 1 1 1 1 MYND finger AAA_2 PF07724.9 EIW68261.1 - 9.4e-45 152.5 0.0 1.2e-43 148.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EIW68261.1 - 5.1e-19 67.9 1.2 1.1e-18 66.9 0.1 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EIW68261.1 - 3.9e-18 65.9 0.0 9.6e-09 35.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW68261.1 - 1.1e-17 64.0 0.5 1.6e-12 47.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW68261.1 - 4.4e-11 43.0 5.0 0.0025 17.8 0.0 4.7 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EIW68261.1 - 3.4e-08 33.7 0.1 0.00079 19.5 0.0 3.3 2 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EIW68261.1 - 3.1e-07 29.9 0.0 5.9e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 EIW68261.1 - 4.1e-06 27.1 0.1 0.03 14.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain DNA_pol3_delta2 PF13177.1 EIW68261.1 - 1.1e-05 25.1 0.0 5.4e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 EIW68261.1 - 3.5e-05 24.5 2.4 0.042 14.6 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EIW68261.1 - 8.1e-05 22.5 0.0 0.13 12.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EIW68261.1 - 0.00011 21.7 0.0 0.6 9.5 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein MobB PF03205.9 EIW68261.1 - 0.0016 18.1 0.0 0.046 13.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EIW68261.1 - 0.0019 18.2 2.2 3.5 7.5 0.0 4.2 4 1 0 4 4 3 1 AAA domain AAA_19 PF13245.1 EIW68261.1 - 0.0021 17.7 0.0 0.04 13.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 EIW68261.1 - 0.0024 17.0 0.2 1.6 7.8 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EIW68261.1 - 0.0027 17.8 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase T2SE PF00437.15 EIW68261.1 - 0.0027 16.6 0.4 0.04 12.8 0.1 2.4 2 1 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 EIW68261.1 - 0.0028 17.9 0.8 0.41 10.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.1 EIW68261.1 - 0.0045 16.8 0.0 5.7 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 EIW68261.1 - 0.0053 16.6 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 1 1 Torsin AAA_24 PF13479.1 EIW68261.1 - 0.0056 16.2 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIW68261.1 - 0.0056 16.3 7.9 0.23 11.1 0.0 4.4 3 3 0 4 4 4 1 Archaeal ATPase AAA_25 PF13481.1 EIW68261.1 - 0.0063 15.9 4.6 3.2 7.0 0.0 4.3 3 2 0 3 3 3 1 AAA domain DUF2075 PF09848.4 EIW68261.1 - 0.018 14.0 0.0 0.066 12.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EIW68261.1 - 0.019 14.6 0.0 5.1 6.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 EIW68261.1 - 0.02 13.5 0.0 3.1 6.3 0.0 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.18 EIW68261.1 - 0.02 14.8 0.0 0.85 9.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_3 PF07726.6 EIW68261.1 - 0.026 14.1 0.1 2.3 7.8 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EIW68261.1 - 0.027 13.9 0.0 3.5 7.0 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 EIW68261.1 - 0.033 13.6 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 EIW68261.1 - 0.043 12.9 0.0 0.76 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 EIW68261.1 - 0.12 12.8 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 EIW68261.1 - 0.15 11.6 0.0 0.46 9.9 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 EIW68261.1 - 4.9 7.4 22.7 37 4.5 0.0 3.8 3 1 0 3 3 3 0 AAA domain Ytp1 PF10355.4 EIW68262.1 - 8.7e-94 313.7 6.3 8.7e-94 313.7 4.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EIW68262.1 - 6.1e-19 67.5 0.1 6.1e-19 67.5 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Pribosyltran_N PF13793.1 EIW68263.1 - 1.7e-42 143.7 0.1 5e-41 139.0 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EIW68263.1 - 1.1e-40 139.4 1.7 4.2e-33 114.6 0.2 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EIW68263.1 - 4.6e-11 42.5 1.7 3.2e-10 39.8 0.2 2.6 3 0 0 3 3 3 1 Phosphoribosyl transferase domain TIM PF00121.13 EIW68263.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Triosephosphate isomerase 4HBT_3 PF13622.1 EIW68264.1 - 1.1e-27 97.3 0.1 1.9e-27 96.6 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EIW68264.1 - 6.2e-18 64.6 0.0 3.3e-13 49.4 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase Glyco_hydro_3 PF00933.16 EIW68265.1 - 7.6e-59 199.1 0.0 1.1e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW68265.1 - 5.4e-22 78.4 0.0 3.2e-21 75.9 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW68265.1 - 6.2e-20 70.9 0.0 1.1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Acetyltransf_1 PF00583.19 EIW68266.1 - 1.3e-10 41.1 0.0 7.1e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIW68266.1 - 0.00063 19.8 0.0 0.0032 17.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW68266.1 - 0.0016 18.1 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 EIW68266.1 - 0.0083 16.2 0.0 0.41 10.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIW68266.1 - 0.089 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PS_Dcarbxylase PF02666.10 EIW68267.1 - 5.5e-76 254.3 0.0 1e-74 250.2 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Rep_fac_C PF08542.6 EIW68268.1 - 2.3e-20 72.3 0.0 5.3e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EIW68268.1 - 1.4e-13 50.7 0.1 2.6e-11 43.4 0.1 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EIW68268.1 - 1.9e-11 44.2 0.0 3.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EIW68268.1 - 5.7e-07 29.4 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIW68268.1 - 6e-06 26.4 0.2 0.02 15.0 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EIW68268.1 - 1.7e-05 24.9 0.0 0.00044 20.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 EIW68268.1 - 1.7e-05 24.4 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EIW68268.1 - 3.8e-05 22.5 0.1 0.053 12.2 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EIW68268.1 - 5.8e-05 22.2 0.0 0.00012 21.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EIW68268.1 - 9.8e-05 21.9 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EIW68268.1 - 0.00033 20.2 0.1 0.2 11.0 0.0 2.5 2 1 1 3 3 3 2 AAA-like domain AAA_19 PF13245.1 EIW68268.1 - 0.00076 19.1 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EIW68268.1 - 0.001 18.7 0.2 0.0062 16.2 0.1 2.1 1 1 1 2 2 2 1 NTPase Mg_chelatase PF01078.16 EIW68268.1 - 0.0013 17.9 0.0 0.016 14.3 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ArgK PF03308.11 EIW68268.1 - 0.0038 16.0 0.1 0.015 14.0 0.0 1.9 1 1 1 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 EIW68268.1 - 0.0068 15.9 0.0 0.021 14.3 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EIW68268.1 - 0.014 15.7 0.1 0.026 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIW68268.1 - 0.022 14.4 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 EIW68268.1 - 0.023 14.2 0.1 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_11 PF13086.1 EIW68268.1 - 0.038 13.5 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW68268.1 - 0.044 13.9 0.1 0.13 12.4 0.1 1.9 1 1 0 1 1 1 0 RNA helicase Arc_PepC PF06819.6 EIW68268.1 - 0.053 13.4 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain KTI12 PF08433.5 EIW68268.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.17 EIW68268.1 - 0.066 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EIW68268.1 - 0.068 13.4 0.1 0.1 12.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EIW68268.1 - 0.081 12.8 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EIW68268.1 - 0.095 12.1 0.1 1.1 8.7 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase NB-ARC PF00931.17 EIW68268.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ING PF12998.2 EIW68270.1 - 1.2e-12 47.9 0.0 2.4e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EIW68270.1 - 3.3e-08 33.1 8.4 5.3e-08 32.4 5.8 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EIW68270.1 - 0.064 13.4 1.8 0.18 11.9 1.2 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain DUF605 PF04652.11 EIW68272.1 - 0.005 16.2 2.9 0.0057 16.0 2.0 1.1 1 0 0 1 1 1 1 Vta1 like bZIP_1 PF00170.16 EIW68273.1 - 4.1e-05 23.4 5.9 4.1e-05 23.4 4.1 2.0 2 0 0 2 2 2 1 bZIP transcription factor Trypan_PARP PF05887.6 EIW68273.1 - 0.8 9.5 5.7 0.28 11.0 0.2 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4610 PF15384.1 EIW68273.1 - 1 8.8 4.8 7.5 6.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4610) PAT1 PF09770.4 EIW68273.1 - 1.1 7.4 16.2 1.3 7.1 11.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 EIW68273.1 - 2 7.1 5.6 2.8 6.6 3.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4106 PF13388.1 EIW68273.1 - 3.6 6.4 8.8 4.7 6.0 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF605 PF04652.11 EIW68273.1 - 4.3 6.6 17.4 5.2 6.3 12.1 1.1 1 0 0 1 1 1 0 Vta1 like AAA_13 PF13166.1 EIW68274.1 - 0.0047 15.4 18.9 0.007 14.8 13.1 1.1 1 0 0 1 1 1 1 AAA domain DUF2586 PF10758.4 EIW68274.1 - 0.075 12.0 4.2 0.13 11.2 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2586) DUF3584 PF12128.3 EIW68274.1 - 0.093 10.0 26.4 0.13 9.5 18.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 EIW68274.1 - 0.46 9.5 9.6 1.2 8.1 1.3 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 EIW68274.1 - 0.48 9.8 25.5 0.33 10.3 11.8 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF972 PF06156.8 EIW68274.1 - 0.58 10.5 12.9 14 6.0 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 EIW68274.1 - 0.6 9.9 23.9 4.1 7.2 6.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.6 EIW68274.1 - 1.4 7.5 16.1 2 7.0 11.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) LMBR1 PF04791.11 EIW68274.1 - 4.3 5.8 4.8 6 5.3 3.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MULE PF10551.4 EIW68275.1 - 3.3e-05 23.9 0.0 7.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain ADH_zinc_N PF00107.21 EIW68276.1 - 5.2e-17 61.6 0.1 1.3e-16 60.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW68276.1 - 3.4e-14 53.8 0.0 7.5e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW68276.1 - 7.3e-08 32.1 0.1 3.2e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 EIW68277.1 - 8.5 6.3 12.0 15 5.6 8.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Chitin_synth_1 PF01644.12 EIW68279.1 - 3.9e-71 238.1 0.1 5.8e-71 237.5 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EIW68279.1 - 2.5e-26 92.1 0.0 7.4e-20 70.8 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EIW68279.1 - 3.8e-25 87.3 0.0 2.4e-24 84.7 0.0 2.2 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EIW68279.1 - 1.3e-11 44.5 0.1 1.3e-11 44.5 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW68279.1 - 4.7e-10 39.6 0.0 2.4e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF3481 PF11980.3 EIW68279.1 - 0.041 13.7 0.1 0.62 9.9 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) DUF2576 PF10845.3 EIW68279.1 - 0.19 10.8 2.6 0.59 9.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) Glyco_hydro_18 PF00704.23 EIW68280.1 - 8e-85 285.2 0.0 9.2e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1253 PF06862.7 EIW68281.1 - 1.6e-141 471.7 0.0 2.1e-141 471.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Myb_DNA-binding PF00249.26 EIW68282.1 - 4.6e-05 23.3 3.0 8.9e-05 22.4 2.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW68282.1 - 0.0037 17.3 1.7 0.007 16.4 1.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ashwin PF15323.1 EIW68282.1 - 0.0068 16.4 0.7 0.0092 16.0 0.5 1.2 1 0 0 1 1 1 1 Developmental protein Myb_DNA-bind_4 PF13837.1 EIW68282.1 - 0.28 11.3 2.6 0.72 10.0 1.8 1.7 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain HATPase_c PF02518.21 EIW68283.1 - 3.9e-49 165.0 0.0 5.8e-24 83.9 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIW68283.1 - 1.5e-34 118.3 2.0 6.3e-16 58.3 0.0 3.6 3 1 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.20 EIW68283.1 - 4.3e-12 45.8 4.9 3.1e-07 30.2 0.1 3.2 2 1 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EIW68283.1 - 9.4e-07 29.1 0.0 4.2e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.1 EIW68283.1 - 2.7e-06 27.0 0.0 9.1e-06 25.3 0.0 1.9 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.1 EIW68283.1 - 0.00053 19.6 0.0 0.009 15.6 0.0 2.9 3 0 0 3 3 3 1 GHKL domain PAS_4 PF08448.5 EIW68283.1 - 0.00072 19.5 0.0 0.006 16.6 0.0 2.6 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 EIW68283.1 - 0.0019 17.9 0.0 0.0064 16.2 0.0 2.0 1 1 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.1 EIW68283.1 - 0.033 13.9 0.0 0.17 11.6 0.0 2.1 2 1 1 3 3 3 0 Histidine kinase-like ATPase domain GAF_2 PF13185.1 EIW68283.1 - 0.056 13.9 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 GAF domain Sld5 PF05916.6 EIW68284.1 - 1e-07 32.1 0.3 1.8e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 GINS complex protein DUF3984 PF13136.1 EIW68284.1 - 0.97 8.5 3.0 1.6 7.8 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DASH_Spc34 PF08657.5 EIW68285.1 - 8.4e-24 84.6 0.0 5.9e-14 52.3 0.6 2.5 1 1 1 2 2 2 2 DASH complex subunit Spc34 AXE1 PF05448.7 EIW68286.1 - 0.028 12.9 0.0 0.028 12.9 0.0 1.0 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PGK PF00162.14 EIW68287.1 - 9.8e-148 491.7 0.1 1.1e-147 491.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Collagen PF01391.13 EIW68288.1 - 0.0099 15.4 8.1 0.0099 15.4 5.6 1.8 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Zn_clus PF00172.13 EIW68288.1 - 0.047 13.6 7.7 0.3 11.0 5.3 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EIW68288.1 - 0.57 10.3 8.0 4 7.6 1.0 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Amidohydro_4 PF13147.1 EIW68290.1 - 1.8e-11 44.5 0.4 6.3e-10 39.5 0.1 2.5 2 0 0 2 2 2 1 Amidohydrolase Fungal_trans_2 PF11951.3 EIW68290.1 - 5.9e-11 41.5 0.1 1.8e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_3 PF07969.6 EIW68290.1 - 2.3e-08 33.7 1.4 5.8e-08 32.3 0.1 2.0 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.15 EIW68290.1 - 7e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIW68290.1 - 0.00013 21.6 0.2 0.03 14.1 0.1 2.8 2 0 0 2 2 2 2 Amidohydrolase Zn_clus PF00172.13 EIW68290.1 - 0.00073 19.3 11.4 0.0013 18.5 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.23 EIW68291.1 - 2e-23 82.9 0.0 3.7e-23 82.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIW68291.1 - 1.4e-13 50.5 0.0 2.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EIW68291.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 MFS_1 PF07690.11 EIW68292.1 - 7e-31 107.2 24.1 1.1e-30 106.5 16.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW68292.1 - 2e-05 23.0 2.6 3.5e-05 22.2 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2628 PF10947.3 EIW68292.1 - 0.36 10.6 6.4 0.74 9.6 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) MFS_1 PF07690.11 EIW68293.1 - 5.7e-31 107.5 24.1 5.7e-31 107.5 16.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Prefoldin PF02996.12 EIW68294.1 - 3.1e-08 33.2 0.1 5.1e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit NADH-u_ox-rdase PF10785.4 EIW68295.1 - 2.2e-35 120.7 0.5 6e-35 119.3 0.1 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EIW68295.1 - 4.7e-23 80.7 0.0 6.9e-23 80.1 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit zf-RING_2 PF13639.1 EIW68296.1 - 8.8e-14 51.0 5.0 1.4e-13 50.4 3.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIW68296.1 - 1.8e-09 37.1 3.8 3.1e-09 36.3 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIW68296.1 - 6.8e-09 35.7 4.8 1.2e-08 34.9 3.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIW68296.1 - 1.1e-08 34.6 4.2 1.6e-08 34.0 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW68296.1 - 1.3e-07 31.4 4.2 2.2e-07 30.7 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW68296.1 - 5.2e-07 29.2 3.4 8.7e-07 28.5 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW68296.1 - 0.00058 19.6 2.1 0.0011 18.7 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EIW68296.1 - 0.0049 16.5 2.7 0.012 15.2 1.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.2 EIW68296.1 - 0.012 15.6 5.3 0.022 14.7 3.6 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EIW68296.1 - 0.013 15.0 4.8 0.023 14.2 3.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EIW68296.1 - 0.16 11.8 1.6 0.28 11.0 1.1 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain DUF3045 PF11243.3 EIW68296.1 - 0.19 11.9 0.1 0.45 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) PHD PF00628.24 EIW68296.1 - 0.22 11.2 5.1 0.38 10.4 3.5 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EIW68296.1 - 0.31 11.0 3.0 0.65 9.9 2.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EIW68296.1 - 0.32 11.0 7.0 0.59 10.1 4.9 1.4 1 0 0 1 1 1 0 RING-like domain DUF1451 PF07295.6 EIW68297.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) HTH_Tnp_Tc3_2 PF01498.13 EIW68299.1 - 2.2e-06 27.6 0.1 2.8e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Transposase Cas_Csy1 PF09611.5 EIW68299.1 - 0.15 10.9 1.5 0.18 10.7 1.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) DUF4268 PF14088.1 EIW68300.1 - 0.095 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Translin PF01997.11 EIW68301.1 - 5.1e-35 120.9 0.0 6.1e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Translin family MCM PF00493.18 EIW68302.1 - 1.6e-139 464.3 0.2 2.8e-139 463.5 0.1 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EIW68302.1 - 2.6e-24 86.0 15.9 2.6e-24 86.0 11.0 1.9 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EIW68302.1 - 1.2e-17 64.5 0.1 3.3e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIW68302.1 - 2.8e-07 29.8 0.0 9e-06 24.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIW68302.1 - 8.7e-07 28.7 0.0 2.2e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIW68302.1 - 0.00013 21.5 0.0 0.0069 15.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW68302.1 - 0.0083 15.6 0.1 0.036 13.5 0.1 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.9 EIW68302.1 - 0.034 14.1 0.1 0.083 12.9 0.1 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA PF00004.24 EIW68302.1 - 0.1 12.8 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.27 EIW68303.1 - 3.8e-05 23.3 3.7 1.2 9.1 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.10 EIW68303.1 - 0.0055 15.8 0.0 0.18 10.8 0.0 2.2 1 1 1 2 2 2 2 CPSF A subunit region UDPGT PF00201.13 EIW68305.1 - 1.1e-14 53.9 0.1 1.6e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase NDUFA12 PF05071.11 EIW68306.1 - 3.4e-08 33.8 0.1 1e-07 32.3 0.0 1.9 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF2413 PF10310.4 EIW68306.1 - 0.042 12.6 0.1 0.062 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) IF-2B PF01008.12 EIW68307.1 - 8.3e-61 205.4 0.0 9.5e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family IGF2_C PF08365.6 EIW68311.1 - 0.0083 15.8 8.1 0.15 11.8 0.3 2.5 2 0 0 2 2 2 2 Insulin-like growth factor II E-peptide GPI-anchored PF10342.4 EIW68312.1 - 0.34 11.4 4.8 0.21 12.0 0.7 2.4 2 1 1 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MFS_2 PF13347.1 EIW68313.1 - 3.2e-14 52.1 11.0 3.2e-14 52.1 7.6 3.0 3 0 0 3 3 3 1 MFS/sugar transport protein bZIP_C PF12498.3 EIW68313.1 - 7.2 7.8 9.1 4.1 8.6 4.9 1.6 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Ribosomal_L7Ae PF01248.21 EIW68314.1 - 3.8e-26 90.4 0.0 4.9e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EIW68314.1 - 0.0018 18.1 0.1 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EIW68314.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain BRO1 PF03097.13 EIW68315.1 - 1.5e-97 326.6 0.0 2.6e-97 325.9 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EIW68315.1 - 2.5e-67 226.9 1.1 4.5e-67 226.0 0.7 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV FlgN PF05130.7 EIW68315.1 - 0.011 15.9 2.7 0.35 11.1 0.1 3.5 3 0 0 3 3 3 0 FlgN protein DUF2418 PF10332.4 EIW68316.1 - 6.2e-24 84.1 0.3 6.2e-24 84.1 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) SPC25 PF06703.6 EIW68319.1 - 2.3e-24 85.8 0.0 5.9e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) UDPGT PF00201.13 EIW68320.1 - 1.1e-15 57.2 0.1 1.5e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase bZIP_1 PF00170.16 EIW68321.1 - 1.4e-06 28.1 6.2 2.1e-06 27.5 4.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIW68321.1 - 9.2e-05 22.1 7.8 0.00015 21.5 5.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper HrpB7 PF09486.5 EIW68321.1 - 0.00054 19.9 5.3 0.00075 19.4 3.7 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) bZIP_Maf PF03131.12 EIW68321.1 - 0.002 18.3 3.9 0.0027 17.9 2.7 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor PspA_IM30 PF04012.7 EIW68321.1 - 0.015 14.7 1.0 0.019 14.3 0.7 1.2 1 0 0 1 1 1 0 PspA/IM30 family APP_E2 PF12925.2 EIW68321.1 - 0.023 14.2 0.5 0.029 13.9 0.4 1.1 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein Atg14 PF10186.4 EIW68321.1 - 0.067 12.1 1.4 0.089 11.7 1.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 EIW68321.1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Prefoldin subunit EFhand_Ca_insen PF08726.5 EIW68321.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF2968 PF11180.3 EIW68321.1 - 0.11 11.8 3.3 0.15 11.4 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF2399 PF09664.5 EIW68321.1 - 0.12 12.2 0.7 0.59 9.9 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2399) DUF4140 PF13600.1 EIW68321.1 - 0.16 12.4 2.0 0.22 11.9 1.0 1.5 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) HR1 PF02185.11 EIW68321.1 - 0.18 11.5 0.8 0.27 10.9 0.6 1.4 1 1 0 1 1 1 0 Hr1 repeat Bac_rhodopsin PF01036.13 EIW68322.1 - 9.3e-42 142.8 19.1 1.1e-41 142.6 13.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF998 PF06197.8 EIW68322.1 - 0.51 9.6 26.0 0.35 10.1 3.2 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF998) Tetraspannin PF00335.15 EIW68322.1 - 9 5.5 7.9 0.35 10.1 0.3 2.0 2 0 0 2 2 2 0 Tetraspanin family ABC_tran PF00005.22 EIW68323.1 - 1.3e-42 145.3 0.0 2.2e-22 79.8 0.0 3.4 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW68323.1 - 1.7e-35 122.7 32.6 4.2e-23 82.1 12.9 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EIW68323.1 - 3e-13 49.5 0.0 4.3e-08 32.6 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW68323.1 - 1.6e-06 27.6 0.0 0.0026 17.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW68323.1 - 2.2e-06 27.8 0.1 0.44 10.6 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 EIW68323.1 - 4.8e-06 26.7 0.2 6.5 6.6 0.0 4.4 4 0 0 4 4 4 0 AAA domain AAA_10 PF12846.2 EIW68323.1 - 1.1e-05 25.0 0.0 0.12 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_29 PF13555.1 EIW68323.1 - 1.3e-05 24.6 0.7 0.093 12.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EIW68323.1 - 1.9e-05 25.0 0.1 0.031 14.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EIW68323.1 - 2.1e-05 23.5 0.0 0.17 10.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.1 EIW68323.1 - 0.00015 21.6 0.0 0.17 11.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EIW68323.1 - 0.00017 21.3 0.7 0.35 10.5 0.2 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIW68323.1 - 0.00037 21.3 2.2 0.91 10.3 0.9 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIW68323.1 - 0.00042 20.3 5.4 0.21 11.5 0.1 3.8 3 1 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.1 EIW68323.1 - 0.00086 19.6 0.2 1.2 9.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EIW68323.1 - 0.0012 18.6 0.3 0.062 13.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 EIW68323.1 - 0.0021 18.5 0.1 2.4 8.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 EIW68323.1 - 0.0033 16.9 1.1 0.047 13.1 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EIW68323.1 - 0.0056 16.3 1.4 0.39 10.3 0.3 2.7 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.1 EIW68323.1 - 0.01 15.7 0.2 1.8 8.5 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EIW68323.1 - 0.011 15.4 0.1 0.24 11.1 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain DUF258 PF03193.11 EIW68323.1 - 0.015 14.5 0.0 0.64 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIW68323.1 - 0.018 14.8 2.3 0.097 12.4 0.1 2.6 3 0 0 3 3 2 0 Dynamin family AAA_24 PF13479.1 EIW68323.1 - 0.018 14.6 0.4 0.74 9.3 0.3 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EIW68323.1 - 0.021 14.7 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EIW68323.1 - 0.026 14.0 1.5 1.3 8.4 0.2 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 EIW68323.1 - 0.036 13.9 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EIW68323.1 - 0.039 12.5 0.5 3.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 EIW68323.1 - 0.056 12.9 0.1 5.8 6.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 EIW68323.1 - 0.061 12.0 0.0 0.14 10.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 EIW68323.1 - 0.1 12.8 0.5 4.6 7.4 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EIW68323.1 - 0.11 12.1 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 EIW68323.1 - 0.13 11.1 0.3 7.7 5.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EIW68323.1 - 0.13 11.3 0.2 8.2 5.4 0.0 2.4 2 0 0 2 2 2 0 KaiC GTP_EFTU PF00009.22 EIW68323.1 - 0.15 11.4 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.7 EIW68323.1 - 0.17 10.9 0.1 5.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.7 EIW68323.1 - 0.19 10.9 0.2 9.6 5.4 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Zot PF05707.7 EIW68323.1 - 0.28 10.6 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) NTPase_1 PF03266.10 EIW68323.1 - 0.31 10.7 1.5 6.5 6.4 0.0 2.4 2 0 0 2 2 2 0 NTPase Septin PF00735.13 EIW68323.1 - 0.34 9.9 0.0 4.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Septin Acid_PPase PF12689.2 EIW68324.1 - 1.5e-42 145.1 0.0 1.9e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EIW68324.1 - 0.00095 19.4 0.6 0.013 15.7 0.5 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIW68325.1 - 1.5e-63 213.9 0.8 3.9e-63 212.5 0.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EIW68325.1 - 2.3e-22 80.5 0.1 5e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW68325.1 - 6.5e-13 49.2 0.0 1.3e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIW68325.1 - 1.5e-10 40.3 0.0 4e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIW68325.1 - 0.0056 16.2 0.0 0.0056 16.2 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW68325.1 - 0.03 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit N_NLPC_P60 PF12912.2 EIW68325.1 - 0.19 11.8 2.7 0.17 12.0 0.6 1.8 2 0 0 2 2 2 0 NLPC_P60 stabilising domain, N term RAP1 PF07218.6 EIW68326.1 - 0.063 11.3 4.0 0.091 10.8 2.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Aminotran_1_2 PF00155.16 EIW68328.1 - 3.6e-32 111.7 0.0 5.2e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MAS20 PF02064.10 EIW68330.1 - 2.1e-20 72.8 0.9 5.9e-20 71.3 0.6 1.6 1 1 0 1 1 1 1 MAS20 protein import receptor DUF2357 PF09823.4 EIW68330.1 - 0.015 14.4 0.1 0.019 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Coatomer_WDAD PF04053.9 EIW68332.1 - 2.4e-145 484.7 0.0 4.2e-145 483.9 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EIW68332.1 - 5.9e-98 328.1 0.0 8.9e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EIW68332.1 - 3.4e-54 178.9 12.2 4e-10 39.1 0.3 8.2 9 0 0 9 9 9 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIW68332.1 - 0.0058 15.4 0.2 0.84 8.3 0.0 3.0 2 1 1 3 3 3 1 Nup133 N terminal like Clathrin PF00637.15 EIW68332.1 - 0.066 12.8 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_14 PF13428.1 EIW68332.1 - 2.6 8.9 6.6 41 5.2 0.5 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat UDPGT PF00201.13 EIW68333.1 - 4.5e-10 38.6 0.0 6.2e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Polysacc_deac_1 PF01522.16 EIW68334.1 - 3.9e-25 87.8 0.0 7e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.4 EIW68334.1 - 0.0057 15.9 0.0 0.0057 15.9 0.0 2.3 3 0 0 3 3 3 1 Virulence protein nec1 Macoilin PF09726.4 EIW68334.1 - 8.8 4.4 5.9 12 4.0 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein VPEP PF07589.6 EIW68334.1 - 9.4 6.2 12.3 2.1 8.3 0.1 2.7 2 0 0 2 2 2 0 PEP-CTERM motif RIC1 PF07064.8 EIW68335.1 - 1.6e-75 253.9 1.1 2.2e-75 253.4 0.8 1.2 1 0 0 1 1 1 1 RIC1 Kelch_6 PF13964.1 EIW68335.1 - 0.072 13.2 0.0 5.2 7.4 0.0 2.9 2 0 0 2 2 2 0 Kelch motif AAA PF00004.24 EIW68336.1 - 4e-18 65.9 0.0 4e-17 62.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW68336.1 - 0.0012 19.6 0.3 0.0029 18.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW68336.1 - 0.0068 16.4 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 EIW68336.1 - 0.0097 15.5 0.1 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EIW68336.1 - 0.015 14.2 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.7 EIW68336.1 - 0.016 14.3 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIW68336.1 - 0.037 14.1 0.0 0.077 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIW68336.1 - 0.037 13.9 0.1 0.052 13.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW68336.1 - 0.053 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 EIW68336.1 - 0.069 13.1 0.1 0.21 11.5 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_11 PF13086.1 EIW68336.1 - 0.073 12.6 0.2 0.46 10.0 0.2 1.7 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 EIW68336.1 - 0.082 12.6 0.1 0.27 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TFIIIC_delta PF12657.2 EIW68336.1 - 0.087 12.5 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term AAA_29 PF13555.1 EIW68336.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_3 PF07726.6 EIW68336.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 EIW68337.1 - 7.1e-63 212.1 0.4 1.4e-41 142.4 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW68337.1 - 3.2e-27 95.2 0.8 7.5e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EIW68337.1 - 0.00013 21.0 0.2 0.0055 15.8 0.0 2.7 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIW68337.1 - 0.00061 18.8 0.0 0.0013 17.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 EIW68337.1 - 0.0016 18.9 0.4 0.0056 17.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.18 EIW68337.1 - 0.0036 17.0 0.2 0.16 11.6 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIW68337.1 - 0.034 12.9 0.1 0.064 12.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EIW68337.1 - 0.077 11.8 0.1 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 NUFIP1 PF10453.4 EIW68337.1 - 0.099 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) ABC_membrane PF00664.18 EIW68338.1 - 6.6e-63 212.6 33.4 3.9e-34 118.3 7.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW68338.1 - 2.9e-50 170.1 0.3 5.3e-27 94.7 0.1 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EIW68338.1 - 9.3e-09 34.8 6.4 1.9e-05 24.0 0.8 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW68338.1 - 1.6e-07 31.5 0.5 0.05 13.5 0.0 4.5 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EIW68338.1 - 1.6e-05 24.9 1.5 0.0061 16.5 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.18 EIW68338.1 - 1.7e-05 24.7 0.0 0.13 12.2 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EIW68338.1 - 2.2e-05 23.9 5.0 0.018 14.5 0.1 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EIW68338.1 - 4.2e-05 23.0 0.0 0.013 14.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EIW68338.1 - 4.7e-05 23.8 0.5 0.46 11.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EIW68338.1 - 0.00043 21.0 0.4 0.95 10.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIW68338.1 - 0.00072 18.7 1.8 0.56 9.3 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EIW68338.1 - 0.0056 17.0 11.5 0.15 12.3 0.1 4.3 5 1 0 6 6 4 2 AAA domain AAA_15 PF13175.1 EIW68338.1 - 0.0075 15.3 0.0 1.1 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 EIW68338.1 - 0.018 13.6 1.5 0.38 9.3 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EIW68338.1 - 0.019 14.6 0.5 0.13 11.8 0.0 2.5 3 0 0 3 3 3 0 NACHT domain ArgK PF03308.11 EIW68338.1 - 0.022 13.5 0.2 0.76 8.5 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EIW68338.1 - 0.025 14.8 0.2 11 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EIW68338.1 - 0.037 13.8 2.4 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 EIW68338.1 - 0.052 13.0 0.3 4 6.8 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EIW68338.1 - 0.053 12.9 1.4 3.5 6.9 0.3 2.4 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 EIW68338.1 - 0.055 13.1 0.1 0.38 10.4 0.0 2.4 4 0 0 4 4 2 0 Archaeal ATPase MobB PF03205.9 EIW68338.1 - 0.071 12.8 0.5 3.9 7.1 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EIW68338.1 - 0.1 12.7 1.8 22 5.1 0.1 3.2 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EIW68338.1 - 0.15 11.5 1.1 6.9 6.1 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3844 PF12955.2 EIW68338.1 - 0.35 11.0 0.0 1.1 9.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) ABC_ATPase PF09818.4 EIW68338.1 - 0.39 9.2 1.8 2.8 6.4 0.1 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class cobW PF02492.14 EIW68338.1 - 0.56 9.6 1.7 2.7 7.4 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EIW68338.1 - 0.79 9.4 6.4 0.53 10.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Adenylsucc_synt PF00709.16 EIW68340.1 - 8.5e-162 538.5 0.0 9.7e-162 538.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase C2 PF00168.25 EIW68341.1 - 7.4e-11 41.7 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain Adaptin_N PF01602.15 EIW68342.1 - 9.6e-128 426.7 4.2 1.2e-127 426.3 2.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EIW68342.1 - 6.1e-37 126.0 0.0 3.3e-36 123.6 0.0 2.2 3 0 0 3 3 3 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EIW68342.1 - 1.7e-16 60.5 0.0 4.5e-16 59.1 0.0 1.7 2 0 0 2 2 2 1 Adaptin C-terminal domain F-box PF00646.28 EIW68343.1 - 0.00015 21.3 2.3 0.0004 19.9 0.0 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EIW68343.1 - 0.00086 18.9 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like Ctf8 PF09696.5 EIW68344.1 - 4.4e-15 55.5 5.0 4.3e-08 32.9 0.1 3.4 2 1 0 2 2 2 2 Ctf8 DUF4658 PF15555.1 EIW68344.1 - 4.1 7.3 5.7 0.89 9.4 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) HAD PF12710.2 EIW68345.1 - 2.8e-16 60.2 0.0 4.5e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIW68345.1 - 4.6e-07 30.2 0.0 1.6e-06 28.4 0.0 1.9 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EIW68345.1 - 2.4e-05 23.6 0.0 7.6e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.21 EIW68345.1 - 5.3e-05 23.7 0.0 0.017 15.5 0.0 3.3 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EIW68345.1 - 0.0015 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Glyco_hydro_cc PF11790.3 EIW68346.1 - 1.5e-32 112.9 0.5 2.1e-32 112.4 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Phosphodiest PF01663.17 EIW68346.1 - 0.052 12.8 0.0 0.064 12.5 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase API5 PF05918.6 EIW68346.1 - 0.49 8.8 6.4 0.65 8.4 4.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-C2H2 PF00096.21 EIW68347.1 - 3 8.3 25.8 0.053 13.8 1.1 5.4 6 0 0 6 6 6 0 Zinc finger, C2H2 type DUF3138 PF11336.3 EIW68349.1 - 0.089 10.9 0.0 0.094 10.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) F-box-like PF12937.2 EIW68350.1 - 0.015 14.9 0.1 0.032 13.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 EIW68351.1 - 0.00059 19.5 0.3 0.0016 18.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW68351.1 - 0.00069 19.2 0.3 0.0018 17.8 0.2 1.7 1 0 0 1 1 1 1 F-box domain NUDIX PF00293.23 EIW68352.1 - 4.2e-17 62.0 0.0 8.1e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EIW68352.1 - 1.1e-10 41.6 0.0 2.7e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EIW68352.1 - 0.0017 17.8 0.3 0.0032 16.9 0.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Spatacsin_C PF14649.1 EIW68353.1 - 0.069 12.0 0.0 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 Spatacsin C-terminus Semialdhyde_dh PF01118.19 EIW68354.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Nfu_N PF08712.6 EIW68356.1 - 1.7e-27 94.8 0.0 4.4e-27 93.5 0.0 1.6 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EIW68356.1 - 4e-23 80.9 0.1 5.8e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 EIW68356.1 - 0.086 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus UBN2_2 PF14227.1 EIW68357.1 - 2.9e-08 33.2 0.0 8.6e-08 31.7 0.0 1.8 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW68357.1 - 3.7e-07 29.9 0.0 8.9e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW68357.1 - 0.012 15.2 3.4 15 5.0 0.0 3.3 4 0 0 4 4 4 0 gag-polypeptide of LTR copia-type PEX11 PF05648.9 EIW68358.1 - 8.6e-09 34.9 0.6 1.1e-06 28.0 0.1 2.3 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Sugar_tr PF00083.19 EIW68359.1 - 2.2e-68 230.8 14.0 2.2e-68 230.8 9.7 1.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW68359.1 - 1.1e-19 70.3 33.5 3.7e-11 42.3 6.3 2.3 3 0 0 3 3 3 2 Major Facilitator Superfamily Cyclin_N PF00134.18 EIW68360.1 - 2e-14 53.2 0.0 3.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIW68360.1 - 7.8e-12 45.8 0.0 1.3e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Copper-fist PF00649.13 EIW68362.1 - 2.2e-21 74.7 0.4 2.2e-21 74.7 0.3 2.2 2 0 0 2 2 2 1 Copper fist DNA binding domain Ribosomal_S9 PF00380.14 EIW68364.1 - 3.3e-35 120.9 0.1 6.9e-35 119.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BolA PF01722.13 EIW68365.1 - 7.1e-21 73.9 0.1 9.1e-21 73.6 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Mito_carr PF00153.22 EIW68366.1 - 1e-59 198.2 0.8 1.6e-20 72.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PHD PF00628.24 EIW68367.1 - 1.9e-16 59.4 18.1 1.9e-10 40.2 5.0 2.8 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 EIW68367.1 - 0.0017 18.0 9.3 0.028 14.1 0.0 2.9 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DnaJ_CXXCXGXG PF00684.14 EIW68367.1 - 0.028 14.4 7.3 0.66 10.0 0.0 3.1 3 0 0 3 3 3 0 DnaJ central domain zf-HC5HC2H PF13771.1 EIW68367.1 - 0.064 13.4 6.1 0.041 14.0 1.1 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.1 EIW68367.1 - 0.75 9.0 9.1 4.7 6.4 3.3 3.0 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.6 EIW68367.1 - 8.1 6.5 13.4 0.99 9.4 0.4 2.8 2 0 0 2 2 2 0 RING-like domain TauD PF02668.11 EIW68368.1 - 3.3e-46 158.0 0.0 4.2e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DEAD PF00270.24 EIW68369.1 - 1.8e-42 144.7 0.0 1.1e-41 142.1 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW68369.1 - 4.9e-21 74.3 0.0 1.2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EIW68369.1 - 0.0025 17.7 0.1 0.025 14.5 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.10 EIW68369.1 - 0.0041 16.9 0.8 0.35 10.6 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIW68369.1 - 0.0068 15.5 9.0 0.27 10.2 0.0 2.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF2608 PF11019.3 EIW68369.1 - 0.0088 15.0 0.1 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2608) DUF1253 PF06862.7 EIW68369.1 - 0.0092 14.4 0.1 0.56 8.5 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1253) Gluconate_2-dh3 PF13618.1 EIW68369.1 - 0.063 13.4 3.1 0.13 12.3 2.2 1.6 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 CDC37_N PF03234.9 EIW68369.1 - 0.11 12.8 10.2 0.21 11.9 7.1 1.4 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding zf-CCHC_4 PF14392.1 EIW68369.1 - 0.25 11.0 1.3 0.73 9.5 0.9 1.8 1 0 0 1 1 1 0 Zinc knuckle SecA_DEAD PF07517.9 EIW68369.1 - 0.43 9.8 6.8 3.2 6.9 4.7 2.1 1 1 0 1 1 1 0 SecA DEAD-like domain CRM1_C PF08767.6 EIW68370.1 - 4.3e-129 429.9 0.1 4.3e-129 429.9 0.0 2.6 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EIW68370.1 - 1.1e-41 142.1 5.7 1.1e-41 142.1 4.0 2.7 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EIW68370.1 - 1.8e-14 53.4 0.2 1.6e-13 50.3 0.2 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain GAT PF03127.9 EIW68370.1 - 0.23 11.4 2.3 6.2 6.8 0.0 3.7 4 0 0 4 4 4 0 GAT domain Kinesin PF00225.18 EIW68374.1 - 4.6e-109 364.1 0.1 4.6e-109 364.1 0.1 2.1 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bind PF13931.1 EIW68374.1 - 1.8e-09 37.8 0.1 1.8e-09 37.8 0.0 3.3 4 0 0 4 4 4 1 Kinesin-associated microtubule-binding AFG1_ATPase PF03969.11 EIW68375.1 - 1.8e-89 300.1 0.0 5.2e-86 288.7 0.0 2.0 1 1 1 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.1 EIW68375.1 - 0.00063 19.8 0.0 0.002 18.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW68375.1 - 0.001 19.1 0.2 0.14 12.0 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EIW68375.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EIW68375.1 - 0.05 13.7 0.0 0.17 12.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mito_carr PF00153.22 EIW68376.1 - 5.5e-33 112.5 0.2 1.2e-11 44.1 0.0 3.8 3 2 0 3 3 3 3 Mitochondrial carrier protein API5 PF05918.6 EIW68377.1 - 1.1e-09 37.4 0.0 1.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) UAA PF08449.6 EIW68378.1 - 4.4e-14 52.0 16.6 7.1e-14 51.4 11.5 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EIW68378.1 - 1e-08 34.9 3.7 1e-08 34.9 2.5 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family SPX PF03105.14 EIW68379.1 - 1.4e-25 90.5 0.0 7.9e-24 84.8 0.0 2.8 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EIW68379.1 - 1.3e-07 31.3 7.5 2.3e-07 30.5 5.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EIW68379.1 - 5e-07 29.2 6.8 8.3e-07 28.5 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW68379.1 - 1.1e-06 28.5 8.7 1.9e-06 27.7 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW68379.1 - 1.4e-06 27.8 5.8 2.4e-06 27.1 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW68379.1 - 1.6e-06 27.8 6.6 2.7e-06 27.0 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EIW68379.1 - 7.3e-05 22.4 6.9 0.00013 21.6 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EIW68379.1 - 0.00046 19.7 2.5 0.00093 18.7 1.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EIW68379.1 - 0.0038 16.9 5.1 0.01 15.5 3.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EIW68379.1 - 0.027 14.2 2.5 0.055 13.2 1.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EIW68379.1 - 0.13 12.0 1.5 0.3 10.9 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EIW68379.1 - 0.49 10.5 3.2 1.1 9.4 2.2 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EIW68379.1 - 0.51 9.9 5.8 1.4 8.5 4.0 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 EIW68379.1 - 1.1 8.7 5.1 2 8.0 3.5 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RNB PF00773.14 EIW68380.1 - 1e-92 310.8 0.0 3e-92 309.3 0.0 1.8 2 0 0 2 2 2 1 RNB domain OB_RNB PF08206.6 EIW68380.1 - 0.041 13.3 1.0 0.75 9.3 0.2 2.9 2 1 0 2 2 2 0 Ribonuclease B OB domain PRELI PF04707.9 EIW68383.1 - 9.3e-18 64.2 0.0 1.8e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 PRELI-like family Pol_alpha_B_N PF08418.5 EIW68383.1 - 0.61 9.5 7.5 0.91 9.0 5.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CAF-1_p150 PF11600.3 EIW68383.1 - 7.8 5.8 8.7 11 5.2 6.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SCAMP PF04144.8 EIW68384.1 - 1.7e-39 135.5 3.1 2e-39 135.2 2.2 1.1 1 0 0 1 1 1 1 SCAMP family Pil1 PF13805.1 EIW68385.1 - 6.8e-21 74.6 0.0 1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 APG6 PF04111.7 EIW68385.1 - 0.24 10.4 2.7 0.36 9.8 1.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EIW68385.1 - 0.43 9.1 3.0 0.64 8.6 2.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.7 EIW68385.1 - 0.47 10.2 2.9 0.85 9.3 2.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) IncA PF04156.9 EIW68385.1 - 2.1 7.9 5.9 4.6 6.7 3.9 1.7 1 1 0 1 1 1 0 IncA protein 2-Hacid_dh_C PF02826.14 EIW68390.1 - 1.4e-44 151.3 0.0 2e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW68390.1 - 2.5e-21 75.5 0.0 3.4e-21 75.1 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Cpn60_TCP1 PF00118.19 EIW68391.1 - 7.7e-146 486.5 10.8 9.6e-146 486.1 7.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Gpi16 PF04113.9 EIW68392.1 - 1.8e-128 429.0 0.0 2.5e-125 418.6 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component FTHFS PF01268.14 EIW68393.1 - 1.2e-258 858.6 0.1 1.6e-258 858.2 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EIW68393.1 - 4.5e-67 224.1 0.9 7.7e-67 223.3 0.1 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EIW68393.1 - 1.5e-22 79.8 0.1 6.4e-22 77.7 0.0 2.2 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IF2_N PF04760.10 EIW68393.1 - 0.0045 16.5 0.4 6.2 6.5 0.0 3.4 3 0 0 3 3 3 2 Translation initiation factor IF-2, N-terminal region ADH_zinc_N PF00107.21 EIW68394.1 - 1.3e-28 99.0 0.5 2.4e-28 98.2 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW68394.1 - 1.4e-26 92.3 2.1 2.5e-26 91.5 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW68394.1 - 1.6e-05 25.8 0.1 2.6e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_60s PF00428.14 EIW68394.1 - 0.09 13.1 0.3 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein tRNA-synt_1d PF00750.14 EIW68395.1 - 2e-76 257.1 2.7 2.8e-76 256.6 1.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EIW68395.1 - 1.2e-18 67.2 0.0 2.9e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain EF-hand_1 PF00036.27 EIW68396.1 - 8.2e-25 84.1 10.6 1e-06 27.5 0.0 4.9 5 1 1 6 6 6 4 EF hand EF-hand_7 PF13499.1 EIW68396.1 - 2.8e-24 85.0 5.1 4.6e-16 58.7 0.3 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIW68396.1 - 1.3e-21 74.5 4.5 1.5e-05 24.4 0.1 5.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 EIW68396.1 - 3.2e-14 52.2 9.0 4.8e-06 26.0 0.3 3.9 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EIW68396.1 - 3.5e-12 45.0 14.2 0.0018 17.5 0.5 5.3 6 0 0 6 6 6 3 EF hand EF-hand_4 PF12763.2 EIW68396.1 - 1.7e-06 27.7 5.4 0.29 10.9 0.0 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIW68396.1 - 3.2e-05 23.9 2.8 0.027 14.4 0.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EIW68396.1 - 7.4e-05 22.5 1.9 1.2 9.1 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_2 PF09068.6 EIW68396.1 - 0.0038 17.2 0.2 1 9.4 0.0 3.2 3 1 0 3 3 3 1 EF hand EF-hand_10 PF14788.1 EIW68396.1 - 0.0085 15.7 3.1 3.4 7.4 0.1 3.5 3 0 0 3 3 3 1 EF hand S10_plectin PF03501.10 EIW68396.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_3 PF09069.6 EIW68396.1 - 0.1 12.6 0.1 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 EF-hand Pkinase PF00069.20 EIW68397.1 - 9.1e-46 156.1 0.0 3.8e-35 121.2 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW68397.1 - 2.5e-24 85.7 0.0 2.3e-19 69.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RCC1 PF00415.13 EIW68398.1 - 7.1e-50 167.0 17.1 2.4e-08 34.0 0.1 8.9 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIW68398.1 - 3.2e-35 118.9 40.8 1.5e-07 30.8 1.1 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat zf-H2C2_2 PF13465.1 EIW68399.1 - 2.7e-22 77.8 12.4 3.2e-07 30.3 0.2 4.8 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 EIW68399.1 - 1e-17 63.2 20.4 0.00011 22.2 0.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW68399.1 - 2.6e-10 39.8 18.6 0.01 16.1 0.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger XPA_N PF01286.13 EIW68399.1 - 0.017 14.7 0.3 0.045 13.4 0.2 1.7 1 0 0 1 1 1 0 XPA protein N-terminal zf-met PF12874.2 EIW68399.1 - 0.05 13.8 8.0 25 5.2 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW68399.1 - 0.14 12.3 9.9 9.4 6.5 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIW68399.1 - 2.1 8.3 5.9 2.5 8.1 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger FAD_binding_8 PF08022.7 EIW68400.1 - 2.6e-14 52.9 0.0 4.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIW68400.1 - 2.4e-09 37.3 13.7 2.1e-07 31.0 9.5 2.4 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EIW68400.1 - 0.00019 21.3 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF3663 PF12404.3 EIW68402.1 - 0.096 12.4 0.2 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Peptidase CoA_binding PF02629.14 EIW68403.1 - 7.3e-30 103.3 3.1 1.1e-29 102.8 0.2 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EIW68403.1 - 1.1e-23 83.5 0.2 2.1e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EIW68403.1 - 4.1e-08 32.9 0.2 1.4e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EIW68403.1 - 3.4e-05 23.9 0.0 0.00013 22.1 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 EIW68403.1 - 4.7e-05 23.8 0.0 0.00014 22.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sld5 PF05916.6 EIW68404.1 - 0.0058 16.9 0.0 0.0082 16.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein UBA PF00627.26 EIW68405.1 - 0.018 14.8 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Tricho_coat PF05892.6 EIW68405.1 - 0.021 14.0 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Trichovirus coat protein BRO1 PF03097.13 EIW68406.1 - 3.5e-105 351.8 0.5 6e-105 351.0 0.3 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EIW68406.1 - 3.1e-67 226.6 12.0 5.7e-67 225.7 8.3 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV PilJ PF13675.1 EIW68406.1 - 0.078 13.2 8.1 0.055 13.7 0.5 3.9 2 2 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4618 PF15397.1 EIW68406.1 - 3.9 6.7 9.9 1.3 8.2 1.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) HMG_box PF00505.14 EIW68407.1 - 5.9e-12 45.6 0.4 1.5e-11 44.4 0.3 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box Exostosin PF03016.10 EIW68408.1 - 6.4e-40 137.0 0.0 1.4e-39 135.9 0.0 1.5 1 1 0 1 1 1 1 Exostosin family Epimerase PF01370.16 EIW68408.1 - 4.2e-22 78.7 0.0 7.1e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW68408.1 - 1.1e-09 37.4 0.0 6.2e-09 34.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EIW68408.1 - 2.5e-08 33.1 0.0 7.4e-07 28.3 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIW68408.1 - 2.1e-05 23.6 0.1 0.082 11.7 0.0 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.20 EIW68408.1 - 0.0023 17.8 0.1 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EIW68408.1 - 0.01 14.7 0.0 0.43 9.4 0.0 2.5 2 0 0 2 2 2 0 Male sterility protein NAD_binding_10 PF13460.1 EIW68408.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 EIW68408.1 - 0.037 13.6 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 KR domain Saccharop_dh PF03435.13 EIW68409.1 - 3e-109 365.5 0.1 1.3e-108 363.4 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 EIW68409.1 - 6.7e-92 306.8 0.0 1.2e-91 306.0 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EIW68409.1 - 1e-06 28.3 0.0 2.9e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Shikimate_DH PF01488.15 EIW68409.1 - 8.3e-06 25.9 0.0 0.00049 20.1 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 EIW68409.1 - 5.2e-05 23.7 0.0 0.00039 20.9 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW68409.1 - 5.2e-05 23.2 0.0 0.004 17.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIW68409.1 - 0.00047 19.5 0.0 0.0053 16.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EIW68409.1 - 0.00057 20.3 0.1 0.0044 17.4 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 EIW68409.1 - 0.0039 17.2 0.1 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_11 PF08241.7 EIW68409.1 - 0.0047 17.3 0.0 0.54 10.7 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EIW68409.1 - 0.0058 15.8 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 O-methyltransferase DUF43 PF01861.11 EIW68409.1 - 0.0088 15.0 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF43 NAD_binding_7 PF13241.1 EIW68409.1 - 0.013 15.7 0.1 4.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.12 EIW68409.1 - 0.028 14.8 0.0 0.07 13.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_30 PF05430.6 EIW68409.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.7 EIW68409.1 - 0.13 11.1 0.0 0.54 9.0 0.0 1.9 2 0 0 2 2 2 0 DREV methyltransferase PRK PF00485.13 EIW68410.1 - 2.1e-50 171.0 0.0 4.6e-50 169.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EIW68410.1 - 3e-49 167.0 0.0 5.6e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.1 EIW68410.1 - 9.5e-06 25.9 1.2 2.7e-05 24.5 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIW68410.1 - 3.4e-05 24.6 0.2 0.0017 19.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain CPT PF07931.7 EIW68410.1 - 0.0046 16.6 0.0 0.015 14.9 0.0 2.0 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 EIW68410.1 - 0.0098 15.0 0.0 0.028 13.5 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin CoaE PF01121.15 EIW68410.1 - 0.023 14.0 0.6 0.61 9.4 0.1 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase CLASP_N PF12348.3 EIW68411.1 - 1.7e-16 60.2 0.0 1.6e-07 30.9 0.0 4.6 5 0 0 5 5 5 2 CLASP N terminal HEAT PF02985.17 EIW68411.1 - 3.6e-08 32.8 14.8 0.012 15.6 0.1 10.2 12 0 0 12 12 12 1 HEAT repeat Adaptin_N PF01602.15 EIW68411.1 - 3.5e-05 22.3 0.2 0.015 13.6 0.1 2.9 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.1 EIW68411.1 - 0.00064 19.9 20.0 0.13 12.5 0.1 8.0 7 2 1 8 8 8 2 HEAT repeats ParcG PF10274.4 EIW68411.1 - 0.012 15.5 0.1 2 8.3 0.0 3.7 4 0 0 4 4 4 0 Parkin co-regulated protein Proteasom_PSMB PF10508.4 EIW68411.1 - 0.023 12.9 1.0 4.2 5.5 0.0 3.4 4 1 1 5 5 5 0 Proteasome non-ATPase 26S subunit M11L PF11099.3 EIW68411.1 - 0.068 12.9 0.3 0.73 9.5 0.0 2.5 3 0 0 3 3 3 0 Apoptosis regulator M11L like Vac14_Fab1_bd PF12755.2 EIW68411.1 - 0.09 13.1 0.1 1e+02 3.3 0.0 4.8 5 2 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EIW68411.1 - 0.64 10.5 16.8 0.1 13.1 0.2 7.5 8 1 1 9 9 9 0 HEAT-like repeat MFS_1 PF07690.11 EIW68412.1 - 3.2e-30 105.0 92.8 9.1e-24 83.8 46.3 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NUDIX_2 PF13869.1 EIW68413.1 - 3.9e-65 218.7 0.0 4.4e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase SAP PF02037.22 EIW68414.1 - 9.6e-11 40.9 3.3 1.9e-10 39.9 2.3 1.5 1 0 0 1 1 1 1 SAP domain WW PF00397.21 EIW68415.1 - 1.6e-07 31.0 0.2 3.5e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 WW domain DUF4207 PF13904.1 EIW68415.1 - 0.0046 16.3 12.0 0.0086 15.4 8.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) OmpH PF03938.9 EIW68415.1 - 0.33 10.8 8.2 0.53 10.2 5.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Nucleo_P87 PF07267.6 EIW68415.1 - 2.7 6.5 9.3 3.6 6.1 6.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PGBA_C PF15437.1 EIW68415.1 - 4.4 7.5 22.2 0.18 11.9 9.8 2.3 3 0 0 3 3 3 0 Plasminogen-binding protein pgbA C-terminal CDC45 PF02724.9 EIW68415.1 - 9.3 4.1 8.6 14 3.5 6.0 1.3 1 0 0 1 1 1 0 CDC45-like protein SpoIIE PF07228.7 EIW68416.1 - 2.7e-06 27.2 0.1 4.1e-05 23.3 0.1 2.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EIW68416.1 - 0.00093 18.6 0.0 0.14 11.5 0.0 2.3 2 1 0 2 2 2 2 Protein phosphatase 2C Cu-oxidase_3 PF07732.10 EIW68417.1 - 4e-42 142.6 8.9 1.2e-41 141.1 3.3 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EIW68417.1 - 3.2e-34 118.1 0.0 3.3e-31 108.3 0.0 2.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIW68417.1 - 6.9e-34 116.3 4.9 2.4e-27 95.1 0.0 3.2 2 1 0 2 2 2 2 Multicopper oxidase Chromo PF00385.19 EIW68418.1 - 8.8e-12 44.5 0.4 2.8e-11 42.9 0.3 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EIW68418.1 - 1.5e-09 37.5 0.0 3.2e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Chromo shadow domain DTHCT PF08070.6 EIW68418.1 - 0.17 12.5 6.7 0.049 14.2 2.4 1.7 2 0 0 2 2 2 0 DTHCT (NUC029) region Daxx PF03344.10 EIW68418.1 - 6.3 5.1 14.7 8 4.8 10.2 1.1 1 0 0 1 1 1 0 Daxx Family SprT-like PF10263.4 EIW68420.1 - 7e-35 120.0 2.3 1.1e-34 119.3 1.6 1.3 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 EIW68420.1 - 0.051 13.8 0.1 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box Pyr_redox_2 PF07992.9 EIW68421.1 - 4e-23 82.3 0.0 1e-22 81.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW68421.1 - 1.2e-14 54.4 0.0 7.1e-11 42.3 0.0 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 EIW68421.1 - 1.3e-10 41.2 11.4 1.5e-07 31.4 3.4 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EIW68421.1 - 1.3e-08 33.5 10.9 8e-05 21.6 0.2 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EIW68421.1 - 8.8e-08 31.4 4.3 0.0016 18.1 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain Pyr_redox_3 PF13738.1 EIW68421.1 - 1.8e-07 31.4 0.5 0.15 12.0 0.0 4.0 2 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 EIW68421.1 - 1.8e-07 30.6 2.9 0.00017 21.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair YxiJ PF14176.1 EIW68421.1 - 0.0061 16.6 1.9 0.015 15.4 1.3 1.7 1 0 0 1 1 1 1 YxiJ-like protein SPARC_Ca_bdg PF10591.4 EIW68421.1 - 0.0073 16.3 1.1 0.03 14.3 0.2 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region NAD_binding_9 PF13454.1 EIW68421.1 - 0.012 15.3 0.4 4.5 7.0 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding TerB PF05099.8 EIW68421.1 - 0.032 13.9 0.3 0.073 12.8 0.2 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TerB EF-hand_5 PF13202.1 EIW68421.1 - 0.2 11.0 4.5 6.9 6.1 0.4 2.6 2 0 0 2 2 2 0 EF hand PAP1 PF08601.5 EIW68422.1 - 8.5 5.9 20.1 0.14 11.8 8.6 1.9 2 0 0 2 2 2 0 Transcription factor PAP1 Peptidase_M24 PF00557.19 EIW68423.1 - 1.1e-30 106.8 0.0 1.7e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EIW68423.1 - 4.4e-20 72.5 0.0 1.2e-18 67.8 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain YgaB PF14182.1 EIW68423.1 - 0.13 12.4 0.4 0.38 11.0 0.3 1.7 1 0 0 1 1 1 0 YgaB-like protein DUF605 PF04652.11 EIW68424.1 - 8.6 5.6 15.6 11 5.3 10.8 1.1 1 0 0 1 1 1 0 Vta1 like HbrB PF08539.6 EIW68425.1 - 2.3e-23 82.8 0.0 2.5e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 HbrB-like TRAPP PF04051.11 EIW68427.1 - 2e-31 108.5 0.0 2.9e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PIF1 PF05970.9 EIW68429.1 - 0.00016 20.7 0.2 0.00072 18.5 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase EIIBC-GUT_N PF03612.9 EIW68431.1 - 0.057 13.0 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus NPHI_C PF08469.5 EIW68431.1 - 0.11 12.3 0.2 9.1 6.1 0.0 2.1 1 1 1 2 2 2 0 Nucleoside triphosphatase I C-terminal DUF1168 PF06658.7 EIW68432.1 - 0.0054 16.2 7.7 0.0066 15.9 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Peptidase_S49_N PF08496.5 EIW68432.1 - 0.026 14.3 0.5 0.037 13.8 0.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FLO_LFY PF01698.11 EIW68432.1 - 0.032 13.1 3.1 0.032 13.1 2.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein FancD2 PF14631.1 EIW68432.1 - 0.4 7.7 2.2 0.41 7.6 1.5 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF2849 PF11011.3 EIW68432.1 - 0.43 10.8 2.4 0.53 10.5 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2849) PGA2 PF07543.7 EIW68432.1 - 0.77 9.5 6.2 1 9.1 4.3 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 TT_ORF2 PF02957.10 EIW68432.1 - 1.4 9.6 4.4 1.8 9.2 3.0 1.1 1 0 0 1 1 1 0 TT viral ORF2 YqzE PF14038.1 EIW68432.1 - 1.6 8.5 6.8 3 7.6 4.7 1.4 1 0 0 1 1 1 0 YqzE-like protein Prothymosin PF03247.9 EIW68432.1 - 3.9 7.6 14.8 4.1 7.5 9.8 1.3 1 1 0 1 1 1 0 Prothymosin/parathymosin family DUF4604 PF15377.1 EIW68432.1 - 9.9 6.3 15.3 24 5.1 10.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Arginase PF00491.16 EIW68433.1 - 3.3e-77 259.5 0.0 4e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family zf-RING_2 PF13639.1 EIW68434.1 - 0.0014 18.4 0.4 0.0025 17.5 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EIW68434.1 - 0.016 14.9 0.6 0.029 14.0 0.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EIW68434.1 - 0.024 14.3 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EIW68434.1 - 2.5 7.8 5.4 0.22 11.2 0.4 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M24 PF00557.19 EIW68435.1 - 1.2e-34 119.7 0.0 1.6e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C2H2 PF00096.21 EIW68437.1 - 0.026 14.8 1.8 0.063 13.6 1.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type FHA PF00498.21 EIW68439.1 - 2.3e-13 50.0 0.0 4.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Ferric_reduct PF01794.14 EIW68440.1 - 2.8e-17 62.9 6.4 2.8e-17 62.9 4.5 3.0 3 0 0 3 3 3 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIW68440.1 - 1e-12 47.8 0.0 2.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EIW68440.1 - 3.4e-12 46.5 0.0 3.4e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EIW68440.1 - 0.00029 21.3 0.0 1 9.9 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIW68440.1 - 0.00066 19.7 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain zf-CCHC PF00098.18 EIW68443.1 - 0.0029 17.4 2.2 0.0047 16.7 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW68443.1 - 0.019 14.6 1.0 0.054 13.1 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW68443.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW68443.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Ribosomal_60s PF00428.14 EIW68447.1 - 0.27 11.6 2.1 0.94 9.9 1.1 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein PsbH PF00737.15 EIW68448.1 - 0.13 11.8 0.0 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein BPL_LplA_LipB PF03099.14 EIW68449.1 - 4.4e-07 29.9 0.1 1.5e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MFS_1 PF07690.11 EIW68450.1 - 1.7e-36 125.6 31.5 1.7e-36 125.6 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M16 PF00675.15 EIW68451.1 - 2.3e-51 173.4 0.0 4.6e-51 172.4 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIW68451.1 - 1.1e-36 126.2 0.0 1.1e-34 119.7 0.0 2.8 3 0 0 3 3 3 1 Peptidase M16 inactive domain Yip1 PF04893.12 EIW68452.1 - 9.7e-09 34.9 7.4 1.3e-08 34.4 5.1 1.2 1 0 0 1 1 1 1 Yip1 domain Biotin_lipoyl PF00364.17 EIW68455.1 - 1.6e-19 69.3 2.2 2.4e-19 68.7 0.5 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EIW68455.1 - 4.1e-07 29.5 0.1 1.3e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EIW68455.1 - 0.01 15.4 3.8 0.34 10.6 0.0 3.2 2 1 1 3 3 3 0 Biotin-lipoyl like HlyD_2 PF12700.2 EIW68455.1 - 0.08 12.0 2.0 2.8 6.9 1.2 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Mito_carr PF00153.22 EIW68456.1 - 6.1e-60 198.9 0.4 3.6e-22 77.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2458 PF10454.4 EIW68457.1 - 7.4e-06 25.9 0.1 9.5e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DUF3192 PF11399.3 EIW68457.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) TFIIS_C PF01096.13 EIW68458.1 - 2.6e-21 74.9 4.3 2.6e-21 74.9 3.0 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF2387 PF09526.5 EIW68458.1 - 0.0002 21.2 6.9 0.024 14.5 0.7 2.2 1 1 1 2 2 2 2 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.2 EIW68458.1 - 0.0014 18.3 0.6 0.0014 18.3 0.4 2.8 2 1 1 3 3 3 1 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EIW68458.1 - 0.0019 17.9 12.9 0.0065 16.2 0.2 2.8 2 1 0 2 2 2 1 PhnA Zinc-Ribbon DZR PF12773.2 EIW68458.1 - 0.002 17.9 6.5 0.22 11.3 0.8 2.3 2 0 0 2 2 2 2 Double zinc ribbon Lar_restr_allev PF14354.1 EIW68458.1 - 0.0077 16.5 5.3 0.46 10.8 0.3 2.2 2 0 0 2 2 2 2 Restriction alleviation protein Lar RNA_POL_M_15KD PF02150.11 EIW68458.1 - 0.01 15.5 3.5 0.01 15.5 2.4 3.2 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-Di19 PF05605.7 EIW68458.1 - 0.01 15.9 2.6 3.4 7.8 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.1 EIW68458.1 - 0.011 15.3 10.5 0.33 10.6 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIW68458.1 - 0.012 15.1 10.0 0.4 10.3 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 EIW68458.1 - 0.015 15.5 1.0 0.015 15.5 0.7 2.2 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-H2C2_2 PF13465.1 EIW68458.1 - 0.065 13.5 12.8 2.9 8.3 0.0 4.4 4 1 0 4 4 4 0 Zinc-finger double domain zf-DNA_Pol PF08996.5 EIW68458.1 - 0.094 12.0 0.3 0.094 12.0 0.2 1.9 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-RING_3 PF14369.1 EIW68458.1 - 0.16 12.0 11.2 2.1 8.3 3.1 3.0 3 0 0 3 3 3 0 zinc-finger zf-ISL3 PF14690.1 EIW68458.1 - 0.53 10.3 4.7 6.7 6.8 0.0 3.3 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Terminase_GpA PF05876.7 EIW68458.1 - 0.57 8.4 4.3 0.08 11.2 0.5 1.4 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) DUF2296 PF10058.4 EIW68458.1 - 0.93 9.2 9.7 1.3 8.7 0.3 2.7 2 2 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) HypA PF01155.14 EIW68458.1 - 2.2 7.9 7.1 4.7 6.9 0.3 2.7 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EIW68458.1 - 2.3 8.2 0.0 2.3 8.2 0.0 3.5 3 1 0 3 3 3 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 EIW68458.1 - 3.3 7.4 8.7 4.7 6.9 0.6 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-C3HC4_3 PF13920.1 EIW68458.1 - 3.4 7.4 8.3 18 5.1 0.0 3.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.7 EIW68458.1 - 3.7 7.4 10.2 6.5 6.6 0.7 2.5 2 1 0 2 2 2 0 zinc-ribbons Abhydrolase_2 PF02230.11 EIW68459.1 - 7.1e-07 28.8 0.0 0.00016 21.1 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Trehalase PF01204.13 EIW68460.1 - 6.9e-104 348.3 0.9 8.9e-91 305.0 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 EIW68460.1 - 0.0056 15.4 0.2 0.0096 14.6 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase SoxE PF06525.6 EIW68460.1 - 0.011 14.9 0.9 0.011 14.9 0.6 2.6 2 0 0 2 2 2 0 Sulfocyanin (SoxE) EKR PF10371.4 EIW68460.1 - 0.12 11.9 0.1 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function SSP160 PF06933.6 EIW68460.1 - 2 6.3 12.7 0.045 11.7 1.9 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 RRP7 PF12923.2 EIW68461.1 - 1.2e-27 96.5 0.1 1.2e-27 96.5 0.1 2.4 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EIW68461.1 - 0.0019 17.7 0.0 0.0045 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_DNAp_acc PF04929.7 EIW68461.1 - 0.033 13.1 1.6 0.094 11.6 0.4 1.9 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Mit_KHE1 PF10173.4 EIW68462.1 - 3.2e-44 151.0 1.4 5.4e-44 150.2 0.1 2.1 2 1 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Ribosomal_L36e PF01158.13 EIW68464.1 - 1.6e-36 124.1 6.0 1.9e-36 123.9 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.2 EIW68464.1 - 0.088 12.1 0.1 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Ribonuclease_P PF00825.13 EIW68465.1 - 0.00013 21.8 0.1 0.00021 21.1 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease P CCT PF06203.9 EIW68465.1 - 0.11 12.1 0.3 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 CCT motif Adeno_GP19K PF04881.8 EIW68466.1 - 0.16 11.7 0.7 10 5.8 0.1 2.6 1 1 1 2 2 2 0 Adenovirus GP19K RCR PF12273.3 EIW68466.1 - 0.99 9.9 4.8 1.5 9.4 3.3 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF329 PF03884.9 EIW68466.1 - 1.6 8.3 5.3 2.5 7.6 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF329) DUF2256 PF10013.4 EIW68466.1 - 1.9 8.2 6.7 10 5.9 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF581 PF04570.9 EIW68466.1 - 2.1 7.7 4.4 4.8 6.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF581) AhpC-TSA PF00578.16 EIW68468.1 - 8.1e-39 132.1 0.0 1.1e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW68468.1 - 1.5e-18 66.7 0.0 1.8e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EIW68468.1 - 2.5e-11 43.0 0.0 5.9e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin CHD5 PF04420.9 EIW68469.1 - 8e-48 162.1 0.6 1.2e-47 161.5 0.4 1.2 1 0 0 1 1 1 1 CHD5-like protein MIS13 PF08202.6 EIW68470.1 - 1.2e-26 93.5 2.6 1.2e-25 90.2 1.8 2.2 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Serglycin PF04360.7 EIW68470.1 - 0.075 12.7 3.1 0.16 11.6 2.1 1.5 1 0 0 1 1 1 0 Serglycin RRM_1 PF00076.17 EIW68471.1 - 3.9e-14 52.0 0.0 8.2e-14 50.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW68471.1 - 2.4e-08 33.8 0.0 1.4e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW68471.1 - 4.7e-05 23.1 0.0 0.00038 20.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ PF00226.26 EIW68473.1 - 3.2e-20 71.6 0.7 3.2e-20 71.6 0.5 3.0 4 0 0 4 4 4 1 DnaJ domain Pro_isomerase PF00160.16 EIW68474.1 - 1e-45 155.7 0.1 1.2e-45 155.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PI3Ka PF00613.15 EIW68478.1 - 7.6e-50 168.6 0.0 1.2e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EIW68478.1 - 1.7e-44 152.0 0.0 1.3e-42 145.9 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EIW68478.1 - 1.8e-27 95.8 0.0 3.2e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 EIW68478.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Glycos_transf_2 PF00535.21 EIW68480.1 - 1e-30 106.6 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EIW68480.1 - 4.7e-12 46.1 0.0 7.3e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EIW68480.1 - 1.2e-09 37.6 0.0 1.6e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF2587 PF10759.4 EIW68481.1 - 0.038 13.3 0.1 0.11 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PsbQ PF05757.6 EIW68481.1 - 5.3 6.3 7.0 3 7.1 3.0 1.8 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) zf-CCHC PF00098.18 EIW68482.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW68482.1 - 0.35 11.1 8.0 0.092 12.9 3.4 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW68482.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW68483.1 - 0.022 14.1 0.1 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) SR-25 PF10500.4 EIW68483.1 - 6.1 6.2 16.1 0.97 8.8 3.5 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.18 EIW68484.1 - 0.00035 20.3 1.5 0.00053 19.7 1.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW68484.1 - 0.068 12.8 0.9 0.22 11.2 0.6 1.8 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 EIW68484.1 - 0.11 12.4 7.3 0.27 11.1 5.0 1.6 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.1 EIW68484.1 - 0.15 11.7 1.1 0.33 10.7 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.14 EIW68485.1 - 2.9e-13 49.4 0.1 5.6e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease JmjC PF02373.17 EIW68489.1 - 9.9e-11 41.8 0.0 1.8e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EIW68489.1 - 4.8e-06 26.2 0.0 6.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EIW68489.1 - 0.00079 18.7 0.0 0.0011 18.2 0.0 1.2 1 1 0 1 1 1 1 Cupin superfamily protein AMP-binding PF00501.23 EIW68491.1 - 5.7e-77 258.8 0.0 7.5e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIW68491.1 - 1.1e-64 217.7 0.0 2.2e-64 216.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EIW68491.1 - 7.2e-09 35.7 0.0 2e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EIW68491.1 - 7.7e-09 36.3 0.0 2.3e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EIW68491.1 - 4.7e-07 29.4 0.0 8.2e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW68491.1 - 2.6e-05 23.0 0.0 0.00011 21.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 EIW68491.1 - 0.34 9.7 0.0 0.59 8.9 0.0 1.3 1 0 0 1 1 1 0 Condensation domain B12D PF06522.6 EIW68492.1 - 0.0025 17.4 0.2 0.0051 16.4 0.1 1.6 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Cas_Cmr5 PF09701.5 EIW68492.1 - 0.036 14.2 0.0 0.052 13.7 0.0 1.4 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) 4HBT PF03061.17 EIW68493.1 - 1e-06 28.7 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily RWD PF05773.17 EIW68494.1 - 1.4e-18 66.8 0.8 3.1e-18 65.7 0.5 1.6 1 0 0 1 1 1 1 RWD domain TCTP PF00838.12 EIW68494.1 - 0.067 13.1 0.3 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Translationally controlled tumour protein Peptidase_C37 PF05416.7 EIW68494.1 - 1.5 7.0 13.1 2.5 6.3 9.1 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase XPA_C PF05181.7 EIW68495.1 - 9.9e-29 98.6 2.3 9.9e-29 98.6 1.6 1.8 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 EIW68495.1 - 0.012 15.3 3.2 0.012 15.3 2.2 2.2 2 0 0 2 2 2 0 XPA protein N-terminal GAT PF03127.9 EIW68500.1 - 0.00012 21.9 0.4 0.00026 20.8 0.3 1.6 1 0 0 1 1 1 1 GAT domain DUF3837 PF12939.2 EIW68500.1 - 0.036 14.0 0.1 0.076 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) DUF4642 PF15484.1 EIW68500.1 - 0.086 12.8 0.4 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) MFS_1_like PF12832.2 EIW68504.1 - 7.4e-15 54.5 0.2 7.4e-15 54.5 0.2 2.2 2 1 0 2 2 2 1 MFS_1 like family Lig_chan PF00060.21 EIW68504.1 - 1.2 8.7 5.0 2.9 7.5 3.5 1.7 1 1 0 1 1 1 0 Ligand-gated ion channel FMO-like PF00743.14 EIW68505.1 - 9e-28 96.7 0.0 3.5e-22 78.3 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW68505.1 - 1.1e-15 58.2 0.0 1.8e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW68505.1 - 8.7e-12 44.6 0.0 1.6e-10 40.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIW68505.1 - 7.4e-07 29.2 0.0 1.6e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW68505.1 - 0.047 13.4 0.0 0.39 10.4 0.0 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding DUF1273 PF06908.6 EIW68505.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) NAD_binding_8 PF13450.1 EIW68505.1 - 0.051 13.6 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EIW68505.1 - 0.11 12.5 0.0 1.5 8.9 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Cu-oxidase_3 PF07732.10 EIW68506.1 - 1.5e-43 147.2 3.6 6.3e-43 145.2 1.9 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIW68506.1 - 4.2e-33 113.7 2.9 2.4e-26 91.8 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EIW68506.1 - 4.6e-21 75.3 0.0 4.3e-20 72.2 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase SSFA2_C PF14723.1 EIW68507.1 - 0.061 13.0 0.8 0.083 12.6 0.6 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus ABC_membrane PF00664.18 EIW68508.1 - 1.4e-90 303.4 29.2 1.9e-47 161.9 9.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW68508.1 - 3e-69 231.5 0.0 2.1e-33 115.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW68508.1 - 6.4e-13 49.3 0.0 3.3e-05 23.9 0.0 4.2 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIW68508.1 - 1.1e-12 47.6 3.4 0.00033 19.9 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EIW68508.1 - 4.7e-11 41.9 1.8 0.00023 19.8 0.0 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EIW68508.1 - 8.6e-10 39.4 0.0 0.001 19.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW68508.1 - 9.2e-08 31.5 0.8 0.018 14.5 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW68508.1 - 1.7e-07 31.4 4.1 0.00038 20.5 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EIW68508.1 - 1.2e-06 27.8 0.0 0.017 14.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIW68508.1 - 2.2e-06 27.8 0.2 0.21 11.7 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA PF00004.24 EIW68508.1 - 2.2e-06 27.8 0.6 0.066 13.4 0.2 4.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIW68508.1 - 7.9e-06 26.1 0.0 0.055 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EIW68508.1 - 1.1e-05 25.2 4.9 0.02 14.8 0.2 4.1 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EIW68508.1 - 1.5e-05 24.2 0.5 0.003 16.6 0.0 2.9 4 0 0 4 4 3 1 Zeta toxin AAA_5 PF07728.9 EIW68508.1 - 3.6e-05 23.5 0.2 0.73 9.5 0.0 4.1 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EIW68508.1 - 0.0001 21.9 0.0 4 6.9 0.0 3.6 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.15 EIW68508.1 - 0.00025 19.8 0.1 0.56 8.8 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MobB PF03205.9 EIW68508.1 - 0.00032 20.3 0.2 1.4 8.5 0.0 3.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EIW68508.1 - 0.00036 20.5 0.1 0.41 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW68508.1 - 0.00042 20.2 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain PRK PF00485.13 EIW68508.1 - 0.00043 19.8 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.20 EIW68508.1 - 0.00044 19.8 0.0 0.31 10.5 0.0 3.4 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 EIW68508.1 - 0.00048 20.0 0.0 0.39 10.6 0.0 4.0 5 0 0 5 5 3 1 AAA domain APS_kinase PF01583.15 EIW68508.1 - 0.00059 19.5 0.2 0.22 11.1 0.0 2.8 3 0 0 3 3 2 1 Adenylylsulphate kinase MMR_HSR1 PF01926.18 EIW68508.1 - 0.00099 19.0 0.2 1.9 8.4 0.0 3.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EIW68508.1 - 0.001 19.4 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW68508.1 - 0.0013 18.8 0.1 1.8 8.7 0.0 3.6 3 0 0 3 3 3 1 RNA helicase AAA_25 PF13481.1 EIW68508.1 - 0.0016 17.8 3.7 0.48 9.7 0.0 3.3 5 0 0 5 5 2 2 AAA domain DUF87 PF01935.12 EIW68508.1 - 0.0016 18.3 0.1 0.28 10.9 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 Mg_chelatase PF01078.16 EIW68508.1 - 0.0041 16.3 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Miro PF08477.8 EIW68508.1 - 0.0046 17.4 0.0 5.4 7.5 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 EIW68508.1 - 0.0079 15.6 1.4 3.1 7.1 0.0 3.5 4 0 0 4 4 4 1 AAA-like domain Rad17 PF03215.10 EIW68508.1 - 0.0083 14.8 0.0 0.053 12.1 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 EIW68508.1 - 0.015 14.7 0.0 5.6 6.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EIW68508.1 - 0.026 13.3 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.8 EIW68508.1 - 0.028 13.3 0.0 1 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF4066 PF13278.1 EIW68508.1 - 0.031 13.5 0.5 13 4.9 0.0 3.4 3 0 0 3 3 3 0 Putative amidotransferase Sigma54_activ_2 PF14532.1 EIW68508.1 - 0.051 13.6 0.0 7.1 6.6 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 EIW68508.1 - 0.071 12.7 0.1 4.6 6.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.1 EIW68508.1 - 0.15 11.0 0.0 5.2 5.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Oxysterol_BP PF01237.13 EIW68509.1 - 3.5e-80 269.1 0.0 4.8e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Adaptin_N PF01602.15 EIW68510.1 - 2.5e-15 55.8 1.6 1.8e-12 46.4 0.5 3.2 2 1 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.17 EIW68510.1 - 0.018 15.1 0.0 2.7 8.3 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat MFS_1 PF07690.11 EIW68511.1 - 8.3e-31 106.9 34.2 1e-30 106.6 23.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily His_Phos_2 PF00328.17 EIW68512.1 - 2.1e-18 66.7 0.0 3.7e-18 65.9 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EIW68512.1 - 0.024 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.11 EIW68513.1 - 1.5e-19 69.9 54.5 4.2e-18 65.1 28.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.16 EIW68514.1 - 6.5e-32 110.7 14.2 8.7e-18 64.2 0.1 2.6 2 1 0 2 2 2 2 POT family Velvet PF11754.3 EIW68516.1 - 1.5e-50 171.6 1.1 1e-33 116.6 0.0 2.4 2 0 0 2 2 2 2 Velvet factor Amidohydro_1 PF01979.15 EIW68517.1 - 4.9e-36 125.0 0.0 6.4e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIW68517.1 - 1e-06 29.0 0.0 0.0035 17.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EIW68517.1 - 5.1e-06 25.9 0.0 0.00057 19.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EIW68517.1 - 5.4e-05 22.9 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Pyr_redox_2 PF07992.9 EIW68518.1 - 7.6e-13 48.7 0.0 0.00044 20.1 0.0 4.2 2 2 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW68518.1 - 2.3e-09 37.5 0.0 1.4e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW68518.1 - 3.6e-06 27.1 0.0 0.00079 19.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW68518.1 - 0.0053 15.6 0.2 0.42 9.4 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW68518.1 - 0.014 14.3 0.1 0.6 8.9 0.0 2.6 2 1 1 3 3 3 0 Lycopene cyclase protein K_oxygenase PF13434.1 EIW68518.1 - 0.06 12.2 0.0 0.12 11.2 0.0 1.6 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) CBF PF03914.12 EIW68520.1 - 9.9e-41 138.9 0.3 2.8e-40 137.4 0.1 1.8 1 1 1 2 2 2 1 CBF/Mak21 family HEAT_EZ PF13513.1 EIW68520.1 - 0.0017 18.7 1.1 0.044 14.2 0.1 3.1 2 1 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.1 EIW68520.1 - 0.048 13.9 0.2 1 9.6 0.0 2.5 1 1 1 2 2 2 0 HEAT repeats DUF3391 PF11871.3 EIW68520.1 - 0.12 12.5 0.3 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) UQ_con PF00179.21 EIW68521.1 - 1.5e-39 134.6 0.0 1.8e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW68521.1 - 0.00035 20.3 0.0 0.0019 17.9 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B PHD PF00628.24 EIW68522.1 - 6.7e-09 35.3 7.6 1.2e-08 34.5 5.3 1.4 1 0 0 1 1 1 1 PHD-finger NMD3 PF04981.8 EIW68522.1 - 7.8e-05 21.9 1.5 0.00012 21.2 1.0 1.2 1 0 0 1 1 1 1 NMD3 family SET PF00856.23 EIW68522.1 - 0.0023 18.2 0.8 0.028 14.7 0.0 3.1 3 1 0 3 3 3 1 SET domain zf-CW PF07496.10 EIW68522.1 - 0.13 11.9 2.5 0.29 10.8 1.7 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.1 EIW68522.1 - 0.19 11.0 4.5 0.35 10.2 3.2 1.4 1 0 0 1 1 1 0 PHD-finger Sec63 PF02889.11 EIW68523.1 - 1.7e-193 641.8 0.1 2.1e-105 352.4 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EIW68523.1 - 6.2e-50 168.9 0.5 6.6e-32 110.3 0.1 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EIW68523.1 - 6.4e-13 48.9 4.8 1.4e-10 41.3 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIW68523.1 - 2.7e-10 39.9 0.0 4.9e-09 35.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EIW68523.1 - 6.7e-08 32.7 0.1 0.0055 16.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain PhoH PF02562.11 EIW68523.1 - 5e-05 22.6 0.0 0.039 13.1 0.0 3.0 3 0 0 3 3 3 2 PhoH-like protein AAA_19 PF13245.1 EIW68523.1 - 0.0025 17.5 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain T2SE PF00437.15 EIW68523.1 - 0.011 14.6 0.0 3.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Helicase_C_2 PF13307.1 EIW68523.1 - 0.016 15.1 0.2 0.7 9.8 0.0 3.3 4 0 0 4 4 4 0 Helicase C-terminal domain MFS_1 PF07690.11 EIW68524.1 - 1.4e-08 33.8 29.2 1.3e-07 30.7 19.6 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EIW68524.1 - 9e-08 31.6 0.4 9e-08 31.6 0.3 2.2 2 1 0 2 2 2 1 Nodulin-like DUF4231 PF14015.1 EIW68524.1 - 3.7 7.5 5.3 0.87 9.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) POT1 PF02765.12 EIW68525.1 - 1.8e-12 47.3 0.0 2.4e-11 43.7 0.0 2.4 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Nop14 PF04147.7 EIW68527.1 - 1.4 6.7 7.3 1.5 6.6 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.18 EIW68528.1 - 0.0038 17.0 4.3 0.008 16.0 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIW68528.1 - 0.0084 15.5 0.2 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Zinc knuckle E1_dh PF00676.15 EIW68531.1 - 4e-115 383.6 0.1 4.7e-115 383.4 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EIW68531.1 - 0.0021 17.6 0.7 0.0021 17.6 0.5 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EIW68531.1 - 0.037 12.9 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Ribosomal_L1 PF00687.16 EIW68532.1 - 2.9e-48 164.1 0.0 5.2e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MFS_1 PF07690.11 EIW68533.1 - 2.4e-24 85.7 53.6 6.6e-16 57.9 16.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW68533.1 - 6.9e-17 61.1 17.2 2.4e-14 52.7 4.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter HMG_box PF00505.14 EIW68534.1 - 2e-22 79.2 0.6 3.9e-22 78.2 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW68534.1 - 1.3e-18 67.1 0.4 1.3e-18 67.1 0.3 1.5 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.8 EIW68534.1 - 0.0032 17.7 0.2 0.0042 17.3 0.1 1.2 1 1 0 1 1 1 1 YABBY protein HMG_box_5 PF14887.1 EIW68534.1 - 0.13 12.0 3.9 0.066 13.0 1.2 1.6 1 1 0 1 1 1 0 HMG (high mobility group) box 5 DUF1074 PF06382.6 EIW68534.1 - 0.34 10.8 2.7 0.37 10.7 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1074) DUF89 PF01937.14 EIW68535.1 - 2.8e-110 368.4 0.0 3.2e-110 368.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Pkinase PF00069.20 EIW68536.1 - 3.7e-55 186.8 0.0 4.4e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW68536.1 - 3.7e-32 111.4 0.0 4.5e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW68536.1 - 6.3e-05 22.0 0.0 0.0007 18.6 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EIW68536.1 - 0.0065 15.3 0.4 0.011 14.5 0.0 1.5 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 EIW68536.1 - 0.14 11.6 0.7 0.37 10.3 0.1 1.9 3 0 0 3 3 3 0 Choline/ethanolamine kinase HMG-CoA_red PF00368.13 EIW68537.1 - 6.9e-159 528.4 4.2 9e-159 528.0 2.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 EIW68537.1 - 5.4e-12 45.4 4.1 1.2e-05 24.8 0.4 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EIW68537.1 - 0.0088 14.0 7.4 0.031 12.2 3.2 2.7 2 1 0 2 2 2 1 Patched family HdeA PF06411.6 EIW68537.1 - 0.24 11.3 0.1 0.61 10.0 0.1 1.6 1 0 0 1 1 1 0 HdeA/HdeB family CDP-OH_P_transf PF01066.16 EIW68538.1 - 2.7e-17 62.9 2.4 2.7e-17 62.9 1.7 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase COG7 PF10191.4 EIW68539.1 - 4.7e-60 203.3 2.6 1.1e-50 172.4 0.2 4.3 2 1 0 3 3 3 3 Golgi complex component 7 (COG7) Baculo_PEP_C PF04513.7 EIW68539.1 - 0.64 9.8 6.1 4.5 7.1 0.6 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC2_membrane PF01061.19 EIW68541.1 - 5.4e-33 113.9 18.3 1e-32 113.0 12.7 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EIW68541.1 - 3.4e-28 98.6 0.0 6.9e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW68541.1 - 4.7e-10 39.9 0.1 3.6e-08 33.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIW68541.1 - 2e-06 27.3 0.0 0.0018 17.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EIW68541.1 - 1.5e-05 24.2 0.0 0.044 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EIW68541.1 - 0.0009 18.4 0.0 0.0022 17.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIW68541.1 - 0.0013 18.2 0.1 0.003 17.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EIW68541.1 - 0.0066 16.7 0.1 0.059 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW68541.1 - 0.0083 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW68541.1 - 0.0096 16.0 0.0 0.038 14.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW68541.1 - 0.011 16.5 0.0 0.025 15.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIW68541.1 - 0.045 13.4 0.1 0.089 12.4 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EIW68541.1 - 0.083 12.8 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EIW68541.1 - 0.11 12.4 0.0 0.42 10.5 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EIW68541.1 - 0.12 12.0 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 EIW68541.1 - 0.12 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 EIW68541.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase hEGF PF12661.2 EIW68541.1 - 0.19 11.8 28.2 0.23 11.6 4.7 4.4 4 0 0 4 4 4 0 Human growth factor-like EGF AAA_33 PF13671.1 EIW68541.1 - 0.19 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EIW68541.1 - 0.2 10.3 0.1 0.35 9.6 0.1 1.3 1 0 0 1 1 1 0 ArgK protein T2SE PF00437.15 EIW68541.1 - 0.22 10.3 0.1 0.39 9.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein EGF_2 PF07974.8 EIW68541.1 - 3.1 8.0 25.7 0.25 11.5 6.0 3.2 3 0 0 3 3 2 0 EGF-like domain zf-primase PF09329.6 EIW68543.1 - 1.1e-15 56.9 3.2 2.2e-15 55.9 2.2 1.5 1 0 0 1 1 1 1 Primase zinc finger Raftlin PF15250.1 EIW68543.1 - 0.9 7.9 3.5 1.9 6.9 2.4 1.5 1 0 0 1 1 1 0 Raftlin Y_phosphatase2 PF03162.8 EIW68544.1 - 2.8e-32 111.3 0.0 3.2e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family CENP-F_leu_zip PF10473.4 EIW68546.1 - 0.051 13.4 0.2 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2312 PF10073.4 EIW68546.1 - 0.059 12.7 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Sigma70_ner PF04546.8 EIW68546.1 - 0.061 12.9 2.5 1.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Oxidored_q6 PF01058.17 EIW68548.1 - 0.092 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Abhydrolase_3 PF07859.8 EIW68552.1 - 5.2e-47 160.1 0.0 7.9e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW68552.1 - 3.5e-09 35.7 0.2 2e-07 29.9 0.1 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIW68552.1 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family NUDIX_2 PF13869.1 EIW68552.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase COesterase PF00135.23 EIW68552.1 - 0.16 10.6 0.0 7.8 5.0 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family LIM PF00412.17 EIW68553.1 - 9.2e-25 86.4 21.1 2e-12 46.9 5.3 2.1 2 0 0 2 2 2 2 LIM domain mono-CXXC PF15626.1 EIW68553.1 - 2.8 7.9 13.8 0.4 10.6 1.1 3.6 3 0 0 3 3 3 0 single CXXC unit DZR PF12773.2 EIW68553.1 - 6.5 6.6 22.7 6.4 6.6 5.1 4.4 2 2 0 2 2 2 0 Double zinc ribbon zf-SNAP50_C PF12251.3 EIW68553.1 - 8.9 5.6 9.1 0.79 9.0 0.5 2.2 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal DNA_pol_B PF00136.16 EIW68554.1 - 4.6e-109 365.2 0.0 6.7e-109 364.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EIW68554.1 - 8.6e-53 178.4 0.0 1.5e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EIW68554.1 - 1.6e-26 92.9 0.0 3.7e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EIW68554.1 - 1.3e-19 69.7 5.3 1.3e-19 69.7 3.7 2.3 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal NUP50 PF08911.6 EIW68554.1 - 0.1 12.9 6.6 0.4 11.0 4.6 2.0 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) YL1 PF05764.8 EIW68554.1 - 2 7.9 20.9 0.07 12.7 5.4 2.4 2 0 0 2 2 2 0 YL1 nuclear protein JAB PF01398.16 EIW68555.1 - 4.4e-13 48.9 0.0 7.1e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EIW68555.1 - 4.4e-05 23.5 0.0 8.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Phage_connect_1 PF05135.8 EIW68555.1 - 0.044 13.9 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein HEAT_2 PF13646.1 EIW68556.1 - 2.8e-11 43.5 10.6 0.22 11.8 0.6 7.7 6 1 1 7 7 7 4 HEAT repeats Adaptin_N PF01602.15 EIW68556.1 - 6e-07 28.1 0.2 0.0032 15.8 0.0 4.3 3 1 1 4 4 4 2 Adaptin N terminal region HEAT PF02985.17 EIW68556.1 - 1.6e-05 24.5 19.9 0.057 13.5 0.1 8.3 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 EIW68556.1 - 0.0011 19.4 13.4 12 6.5 0.1 8.2 7 1 2 9 9 9 2 HEAT-like repeat CLASP_N PF12348.3 EIW68556.1 - 0.0062 15.9 1.0 3.5 6.9 0.0 4.6 4 2 1 5 5 5 1 CLASP N terminal Arm PF00514.18 EIW68556.1 - 0.019 14.7 0.9 16 5.4 0.0 5.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CFEM PF05730.6 EIW68557.1 - 1.4e-11 44.0 18.9 2.6e-11 43.1 13.1 1.5 1 0 0 1 1 1 1 CFEM domain Phasin_2 PF09361.5 EIW68557.1 - 0.15 12.0 2.2 0.33 10.9 1.6 1.6 1 0 0 1 1 1 0 Phasin protein TIL PF01826.12 EIW68557.1 - 0.75 9.9 7.7 1.1 9.3 5.0 1.6 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain NOG1 PF06858.9 EIW68559.1 - 3.7e-29 100.3 0.1 8.1e-29 99.2 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EIW68559.1 - 4.1e-23 80.8 1.7 9.6e-23 79.6 1.2 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EIW68559.1 - 2.4e-17 62.9 0.0 6.6e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW68559.1 - 5.5e-09 35.4 0.0 1.2e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EIW68559.1 - 0.00013 22.4 0.0 0.00032 21.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIW68559.1 - 0.0026 17.5 0.4 1.2 8.9 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EIW68559.1 - 0.0048 16.0 0.0 0.045 12.9 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EIW68559.1 - 0.017 14.8 0.0 0.28 10.8 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 EIW68559.1 - 0.033 13.3 0.0 0.076 12.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family CUE PF02845.11 EIW68560.1 - 1.5e-08 33.9 0.0 2.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain Ribosomal_S5 PF00333.15 EIW68561.1 - 1.4e-28 98.4 1.0 1.4e-28 98.4 0.7 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EIW68561.1 - 1.2e-23 82.1 0.1 2.2e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ras PF00071.17 EIW68562.1 - 1.3e-49 167.6 0.0 1.6e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW68562.1 - 1.9e-19 70.2 0.0 2.8e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW68562.1 - 4.5e-07 29.2 0.0 5.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW68562.1 - 0.00073 19.0 0.0 0.02 14.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW68562.1 - 0.0027 17.6 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EIW68562.1 - 0.0045 16.2 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EIW68562.1 - 0.018 14.5 0.0 3.9 6.9 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EIW68562.1 - 0.06 12.4 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_21 PF13304.1 EIW68562.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.2 EIW68563.1 - 6.6e-07 28.9 0.4 6.6e-07 28.9 0.2 3.5 5 0 0 5 5 5 1 F-box-like F-box PF00646.28 EIW68563.1 - 1e-06 28.1 1.3 0.00034 20.1 0.1 4.1 3 1 1 4 4 4 1 F-box domain LRR_7 PF13504.1 EIW68563.1 - 0.0002 21.0 1.3 47 4.8 0.0 5.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 EIW68563.1 - 0.00045 19.8 0.2 39 4.8 0.1 5.3 4 0 0 4 4 4 0 Leucine Rich Repeat Tcp11 PF05794.8 EIW68564.1 - 6.6e-33 114.0 0.0 8.3e-29 100.5 0.0 3.0 2 1 0 2 2 2 2 T-complex protein 11 Amidohydro_3 PF07969.6 EIW68565.1 - 2.4e-55 188.4 0.1 2.7e-30 105.9 0.0 2.0 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 EIW68565.1 - 2.5e-05 24.1 0.0 0.0025 17.5 0.0 2.8 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIW68565.1 - 0.0027 17.5 0.0 0.012 15.4 0.0 2.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EIW68565.1 - 0.0099 15.9 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase RRM_1 PF00076.17 EIW68566.1 - 1.3e-36 124.0 0.0 1.8e-17 62.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW68566.1 - 1e-28 99.1 0.0 5.6e-13 48.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW68566.1 - 8.2e-11 41.5 0.0 0.00052 19.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4611 PF15387.1 EIW68568.1 - 0.23 11.6 2.2 4.7 7.4 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Gasdermin PF04598.7 EIW68570.1 - 0.078 11.7 0.1 0.094 11.4 0.1 1.2 1 0 0 1 1 1 0 Gasdermin family RGS PF00615.14 EIW68571.1 - 1.1e-10 41.5 0.0 6.1e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF2892 PF11127.3 EIW68571.1 - 0.0063 16.3 0.3 0.016 14.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) FA_desaturase PF00487.19 EIW68571.1 - 9.8 5.5 14.4 1.6 8.0 4.1 2.1 1 1 1 2 2 2 0 Fatty acid desaturase SHS2_Rpb7-N PF03876.12 EIW68572.1 - 2.5e-17 62.7 0.0 3.9e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EIW68572.1 - 4.8e-12 45.7 0.1 7.2e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain PDDEXK_5 PF11645.3 EIW68572.1 - 0.017 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 PD-(D/E)XK endonuclease Pkinase PF00069.20 EIW68573.1 - 1.1e-70 237.7 0.0 1.5e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW68573.1 - 3.6e-37 127.8 0.0 5.2e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW68573.1 - 4.9e-09 35.5 0.0 7.6e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIW68573.1 - 0.00054 19.3 0.1 0.00099 18.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family AMPKBI PF04739.10 EIW68574.1 - 3.4e-23 81.4 1.6 4.8e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain VHS PF00790.14 EIW68575.1 - 5.4e-05 22.8 0.0 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EIW68575.1 - 0.00018 21.3 0.2 0.00036 20.4 0.2 1.4 1 0 0 1 1 1 1 GAT domain zf-RING_UBOX PF13445.1 EIW68576.1 - 2e-13 49.7 0.4 4.2e-13 48.7 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 EIW68576.1 - 1.1e-11 44.6 0.0 2.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 EIW68576.1 - 9e-05 22.2 0.2 0.00019 21.2 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW68576.1 - 0.001 19.0 0.5 0.0019 18.1 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EIW68576.1 - 0.0019 17.4 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.1 EIW68576.1 - 0.0049 16.5 0.2 0.0093 15.6 0.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW68576.1 - 0.03 13.9 0.2 0.047 13.3 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EIW68576.1 - 0.045 13.2 0.2 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 EIW68576.1 - 0.13 11.9 0.3 0.24 11.0 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HD_3 PF13023.1 EIW68577.1 - 1.4e-41 142.0 0.0 2e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 EIW68577.1 - 2.8e-06 27.3 0.0 5.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 HD domain BRCT PF00533.21 EIW68578.1 - 4.4e-11 42.7 0.0 2.4e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DUF1620 PF07774.8 EIW68579.1 - 1.9e-57 194.0 0.0 3e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EIW68579.1 - 2.2e-15 56.7 5.2 1.8e-07 30.8 0.2 3.9 3 1 1 4 4 4 3 PQQ-like domain PQQ PF01011.16 EIW68579.1 - 3.8e-12 45.1 2.5 0.00044 19.6 0.0 5.2 5 0 0 5 5 5 3 PQQ enzyme repeat Sec7 PF01369.15 EIW68580.1 - 4.5e-38 130.8 0.0 8.6e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EIW68580.1 - 4e-22 78.6 0.0 7.4e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain SICA_beta PF12878.2 EIW68580.1 - 0.38 10.5 0.0 0.81 9.4 0.0 1.4 1 0 0 1 1 1 0 SICA extracellular beta domain AflR PF08493.5 EIW68582.1 - 0.065 12.2 1.2 0.075 12.0 0.8 1.0 1 0 0 1 1 1 0 Aflatoxin regulatory protein DnaJ PF00226.26 EIW68583.1 - 5.7e-20 70.8 0.6 5.7e-20 70.8 0.4 2.6 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 EIW68583.1 - 8.4e-19 66.9 16.0 5.4e-13 48.3 0.8 5.4 3 2 2 5 5 5 3 TPR repeat TPR_16 PF13432.1 EIW68583.1 - 2.2e-13 50.4 8.0 1e-09 38.7 1.1 4.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW68583.1 - 1.6e-12 46.4 4.5 2.7e-05 23.5 0.3 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIW68583.1 - 8.1e-11 41.6 3.8 5.1e-08 32.6 0.1 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW68583.1 - 4.5e-10 38.6 19.1 0.0012 18.6 0.5 6.9 9 0 0 9 9 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIW68583.1 - 7.4e-10 39.0 12.0 2.1e-07 31.1 0.9 4.7 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW68583.1 - 3.4e-09 36.1 4.3 0.0041 17.2 0.2 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIW68583.1 - 2.2e-08 33.9 12.7 0.055 14.1 0.2 6.8 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW68583.1 - 1.1e-06 28.7 10.9 0.38 11.3 0.1 6.5 7 1 0 7 7 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW68583.1 - 1.6e-05 24.3 10.4 0.047 13.4 0.2 5.7 5 1 1 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW68583.1 - 1.6e-05 24.9 5.7 0.0019 18.3 1.3 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.3 EIW68583.1 - 0.00036 19.4 0.1 0.00036 19.4 0.1 1.7 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 EIW68583.1 - 0.0029 17.4 1.0 0.45 10.4 0.3 3.6 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 EIW68583.1 - 0.0038 16.9 2.6 2.3 8.2 0.1 5.3 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW68583.1 - 0.004 17.0 13.1 0.026 14.4 0.6 4.1 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EIW68583.1 - 0.048 13.7 3.7 1.3 9.1 0.2 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIW68583.1 - 0.054 13.9 1.7 0.24 11.9 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Init_tRNA_PT PF04179.7 EIW68583.1 - 0.061 12.1 0.3 0.15 10.9 0.1 1.6 2 0 0 2 2 2 0 Initiator tRNA phosphoribosyl transferase BTAD PF03704.12 EIW68583.1 - 0.23 11.7 6.5 1.9 8.8 0.1 3.4 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Helitron_like_N PF14214.1 EIW68584.1 - 2.3e-19 69.8 0.0 4.1e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4231 PF14015.1 EIW68585.1 - 0.0019 18.1 1.5 0.0026 17.7 1.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4231) Oxidored_q3 PF00499.15 EIW68585.1 - 0.034 13.9 1.3 0.043 13.5 0.9 1.0 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 BPD_transp_1 PF00528.17 EIW68585.1 - 0.069 12.6 0.6 0.081 12.4 0.4 1.0 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component CcmD PF04995.9 EIW68585.1 - 8.2 6.2 7.6 1.6 8.5 2.9 1.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) His_Phos_1 PF00300.17 EIW68586.1 - 1.6e-29 103.0 0.0 6.4e-29 101.0 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Amidohydro_2 PF04909.9 EIW68586.1 - 0.09 12.3 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Amidohydrolase PfkB PF00294.19 EIW68587.1 - 4.1e-64 216.5 0.0 4.7e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase NAD_binding_10 PF13460.1 EIW68588.1 - 1.9e-06 27.9 0.0 0.00012 22.0 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding DRIM PF07539.7 EIW68588.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Down-regulated in metastasis DSPc PF00782.15 EIW68589.1 - 1.8e-16 59.9 0.0 8.8e-16 57.6 0.0 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain MR_MLE_C PF13378.1 EIW68589.1 - 0.012 15.6 0.1 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 Enolase C-terminal domain-like Y_phosphatase PF00102.22 EIW68589.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase FLILHELTA PF10306.4 EIW68590.1 - 1.3e-08 34.7 0.1 2.5e-08 33.8 0.1 1.6 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EIW68590.1 - 5.5e-05 23.3 0.9 0.00059 20.0 0.6 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) HAD PF12710.2 EIW68591.1 - 1.8e-15 57.6 0.7 1.5e-09 38.2 0.6 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW68591.1 - 6.4e-14 52.8 1.1 3.6e-06 27.5 0.1 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIW68591.1 - 1.1e-11 44.1 0.2 6.6e-11 41.6 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EIW68591.1 - 5.1e-11 42.3 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIW68591.1 - 0.0006 19.4 0.4 0.009 15.6 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Apt1 PF10351.4 EIW68592.1 - 9.7 4.9 12.7 18 4.0 8.8 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain mRNA_triPase PF02940.10 EIW68593.1 - 2.7e-41 141.6 0.0 3.5e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Ribosom_S12_S23 PF00164.20 EIW68594.1 - 4.1e-46 155.3 2.2 4.6e-46 155.2 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 RRM_DME PF15628.1 EIW68594.1 - 0.057 13.1 0.4 0.091 12.4 0.2 1.3 1 0 0 1 1 1 0 RRM in Demeter zf-B_box PF00643.19 EIW68595.1 - 0.0076 16.1 5.3 0.0076 16.1 3.7 1.9 2 0 0 2 2 2 1 B-box zinc finger RhodobacterPufX PF11511.3 EIW68595.1 - 0.06 12.7 0.3 0.16 11.3 0.2 1.7 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Carn_acyltransf PF00755.15 EIW68596.1 - 1.1e-171 571.9 0.0 1.3e-171 571.6 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase FliJ PF02050.11 EIW68597.1 - 0.0028 17.6 1.7 0.1 12.6 1.5 2.3 2 0 0 2 2 2 1 Flagellar FliJ protein LXG PF04740.7 EIW68597.1 - 0.24 11.1 0.1 0.51 10.0 0.1 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily Viral_env_E26 PF11050.3 EIW68597.1 - 0.39 9.8 0.1 0.68 9.0 0.1 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 NGP1NT PF08153.7 EIW68598.1 - 3.6e-46 156.3 0.0 6.9e-46 155.3 0.0 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EIW68598.1 - 1.3e-18 66.9 0.0 1.7e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW68598.1 - 9.1e-05 21.7 0.2 0.00049 19.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EIW68598.1 - 0.0004 19.8 0.0 0.065 12.6 0.0 3.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EIW68598.1 - 0.00042 19.5 0.0 0.0008 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 EIW68598.1 - 0.0014 17.8 0.0 0.4 9.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF2890 PF11081.3 EIW68598.1 - 3.3 7.7 18.7 4.2 7.3 11.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) SURF2 PF05477.6 EIW68598.1 - 3.6 6.6 16.4 5.8 5.9 11.4 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2404 PF10296.4 EIW68599.1 - 0.0034 17.4 0.0 0.033 14.2 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) NeA_P2 PF12312.3 EIW68599.1 - 0.031 13.5 0.2 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Metallophos PF00149.23 EIW68600.1 - 7.2e-43 146.3 0.1 9e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase KH_1 PF00013.24 EIW68601.1 - 0.0049 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EIW68601.1 - 0.056 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 KH domain RNase_T PF00929.19 EIW68602.1 - 2.9e-18 66.7 0.0 6.5e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Exonuclease AA_permease PF00324.16 EIW68603.1 - 2.8e-115 385.3 37.5 3.5e-115 385.0 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW68603.1 - 8.5e-33 113.5 45.4 2.1e-32 112.2 31.4 1.6 1 1 1 2 2 2 2 Amino acid permease DUF601 PF04642.7 EIW68605.1 - 0.071 12.4 1.5 0.7 9.1 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF601 Sugarporin_N PF11471.3 EIW68605.1 - 2.8 7.6 7.0 6.2 6.5 4.9 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension NUP50 PF08911.6 EIW68606.1 - 0.0043 17.3 0.5 0.0043 17.3 0.3 1.8 2 0 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) Vitellogenin_N PF01347.17 EIW68606.1 - 0.072 11.3 0.0 0.072 11.3 0.0 1.0 1 0 0 1 1 1 0 Lipoprotein amino terminal region Myb_DNA-bind_6 PF13921.1 EIW68607.1 - 3.7e-05 23.7 0.0 6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIW68607.1 - 0.00046 20.1 0.1 0.00079 19.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSP9_HSP12 PF04119.7 EIW68608.1 - 1.1e-23 83.0 3.5 1.3e-23 82.8 2.4 1.1 1 0 0 1 1 1 1 Heat shock protein 9/12 Mlp PF03304.8 EIW68608.1 - 0.035 14.1 0.6 0.035 14.1 0.4 1.1 1 0 0 1 1 1 0 Mlp lipoprotein family MT0933_antitox PF14013.1 EIW68608.1 - 0.037 14.1 2.1 0.17 11.9 1.4 2.1 1 1 0 1 1 1 0 MT0933-like antitoxin protein YpjP PF14005.1 EIW68608.1 - 0.076 12.7 0.1 0.081 12.6 0.1 1.1 1 0 0 1 1 1 0 YpjP-like protein HrpA_pilin PF09589.5 EIW68608.1 - 0.093 13.1 1.1 0.25 11.7 0.6 1.8 1 1 0 1 1 1 0 HrpA pilus formation protein Acetyltransf_7 PF13508.1 EIW68609.1 - 0.0022 18.1 0.0 0.043 13.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW68609.1 - 0.15 12.1 0.1 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Herpes_UL33 PF03581.8 EIW68610.1 - 0.051 13.4 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus UL33-like protein Gp58 PF07902.6 EIW68613.1 - 0.0023 16.2 2.4 0.0026 16.0 1.7 1.2 1 0 0 1 1 1 1 gp58-like protein CALCOCO1 PF07888.6 EIW68613.1 - 0.46 8.7 19.8 0.62 8.2 13.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 EIW68613.1 - 0.64 9.1 2.8 0.51 9.4 1.1 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 EIW68613.1 - 4 7.5 18.9 0.053 13.5 3.3 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Cortex-I_coil PF09304.5 EIW68613.1 - 5.4 7.1 27.1 3.6 7.6 0.6 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil tRNA-synt_2b PF00587.20 EIW68614.1 - 2.9e-33 114.8 0.0 4.4e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EIW68614.1 - 3.9e-19 68.6 3.4 3.9e-19 68.6 2.4 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Homeobox PF00046.24 EIW68615.1 - 7.6e-06 25.4 0.3 2.7e-05 23.6 0.2 1.9 1 0 0 1 1 1 1 Homeobox domain RFX_DNA_binding PF02257.10 EIW68615.1 - 0.017 15.2 0.1 0.55 10.4 0.0 2.5 2 0 0 2 2 2 0 RFX DNA-binding domain OAD_gamma PF04277.8 EIW68615.1 - 0.16 12.3 0.9 0.46 10.8 0.3 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PRAP PF15314.1 EIW68615.1 - 0.17 12.1 3.9 0.13 12.5 0.9 2.2 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine DASH_Duo1 PF08651.5 EIW68616.1 - 5.1e-22 77.2 0.1 8.8e-22 76.4 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 MFS_1 PF07690.11 EIW68617.1 - 1.4e-16 60.2 58.0 1.6e-12 46.8 25.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW68617.1 - 0.0037 15.9 7.8 0.0037 15.9 5.4 2.5 2 2 0 2 2 2 1 Sugar (and other) transporter PsbX PF06596.6 EIW68617.1 - 1.6 8.5 8.4 0.54 9.9 1.0 3.3 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) WD40 PF00400.27 EIW68618.1 - 7.9e-41 136.5 12.9 8.3e-10 38.1 0.2 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.6 EIW68618.1 - 5.7e-13 47.8 1.3 5.7e-13 47.8 0.9 2.2 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EIW68618.1 - 0.0098 15.0 0.2 3.7 6.5 0.0 2.9 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Ank PF00023.25 EIW68619.1 - 3.6e-13 48.6 1.3 2.3e-05 23.9 0.1 3.1 3 0 0 3 3 2 2 Ankyrin repeat Ank_2 PF12796.2 EIW68619.1 - 1.3e-12 47.8 0.2 7e-05 23.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIW68619.1 - 2e-11 43.7 0.2 0.00014 21.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW68619.1 - 4.1e-10 39.9 0.2 4e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW68619.1 - 1.1e-09 37.5 0.6 0.0028 17.7 0.0 3.1 3 0 0 3 3 2 2 Ankyrin repeat KilA-N PF04383.8 EIW68619.1 - 0.00058 19.4 0.8 0.0029 17.2 0.1 2.4 2 1 0 2 2 2 1 KilA-N domain ATG16 PF08614.6 EIW68619.1 - 0.032 14.0 3.4 0.058 13.2 2.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_GPO PF05929.6 EIW68619.1 - 0.071 12.3 0.7 0.11 11.6 0.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_GP20 PF06810.6 EIW68619.1 - 0.099 12.0 1.2 0.18 11.2 0.8 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 CorA PF01544.13 EIW68619.1 - 0.15 11.0 3.2 0.26 10.2 2.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MTBP_C PF14920.1 EIW68619.1 - 0.24 10.8 3.2 0.41 10.0 2.2 1.2 1 0 0 1 1 1 0 MDM2-binding DUF2450 PF10475.4 EIW68619.1 - 0.29 10.0 5.2 2.2 7.0 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) EMP24_GP25L PF01105.19 EIW68619.1 - 4.2 7.0 5.4 6.6 6.3 3.7 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Aminotran_5 PF00266.14 EIW68620.1 - 9e-89 297.7 0.0 1.1e-88 297.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Maf1 PF09174.5 EIW68621.1 - 7.9e-22 77.9 0.1 1.6e-13 50.9 0.0 3.3 3 0 0 3 3 3 2 Maf1 regulator Tim17 PF02466.14 EIW68624.1 - 8e-24 84.1 5.6 9.3e-24 83.9 3.9 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family rRNA_proc-arch PF13234.1 EIW68625.1 - 1.1e-84 283.8 0.0 1.6e-84 283.2 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EIW68625.1 - 7.3e-58 194.7 0.3 1.5e-57 193.7 0.1 1.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EIW68625.1 - 9.8e-21 73.9 0.0 3.3e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW68625.1 - 2.5e-06 27.2 0.0 5.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW68625.1 - 0.017 14.9 0.0 0.18 11.6 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EIW68625.1 - 0.088 11.6 0.0 0.32 9.8 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 EIW68625.1 - 0.16 11.7 0.0 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain DAHP_synth_1 PF00793.15 EIW68627.1 - 3.1e-90 301.5 0.0 3.8e-90 301.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2232 PF09991.4 EIW68628.1 - 0.075 12.0 0.1 0.085 11.8 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SecA_SW PF07516.8 EIW68628.1 - 0.076 12.7 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 SecA Wing and Scaffold domain CBM_3 PF00942.13 EIW68628.1 - 0.093 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Cellulose binding domain TMF_DNA_bd PF12329.3 EIW68630.1 - 0.0066 16.2 0.5 0.012 15.4 0.4 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding FlgM PF04316.8 EIW68630.1 - 0.069 13.0 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Acetyltransf_1 PF00583.19 EIW68631.1 - 5.2e-12 45.6 0.0 7.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW68631.1 - 0.00041 20.4 0.0 0.00064 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW68631.1 - 0.0026 17.4 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EIW68631.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW68631.1 - 0.14 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1348 PF07080.6 EIW68632.1 - 4.7e-50 169.1 4.0 6.1e-50 168.7 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EIW68632.1 - 3.7e-06 27.2 0.9 5e-06 26.8 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EIW68632.1 - 0.022 14.9 0.4 0.032 14.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF3357 PF11837.3 EIW68634.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF2217 PF10265.4 EIW68634.1 - 0.069 11.9 0.2 0.092 11.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4234 PF14018.1 EIW68634.1 - 0.094 12.4 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Sigma_reg_N PF13800.1 EIW68634.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SKG6 PF08693.5 EIW68634.1 - 0.19 11.0 1.8 0.34 10.2 1.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AMA-1 PF02430.10 EIW68634.1 - 0.19 10.5 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 adh_short_C2 PF13561.1 EIW68635.1 - 4.3e-32 111.7 0.0 5e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW68635.1 - 1.4e-27 96.6 0.0 1.7e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW68635.1 - 1.3e-11 44.4 0.0 1.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW68635.1 - 0.014 14.8 0.1 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIW68635.1 - 0.033 13.9 0.1 0.083 12.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PIG-P PF08510.7 EIW68636.1 - 7.1e-27 93.5 3.8 8.5e-27 93.2 2.7 1.1 1 0 0 1 1 1 1 PIG-P DUF3377 PF11857.3 EIW68636.1 - 0.0056 16.2 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DPM2 PF07297.7 EIW68636.1 - 1.3 9.3 5.2 2 8.7 3.6 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Pribosyltran PF00156.22 EIW68637.1 - 4.2e-14 52.3 0.0 5.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIW68637.1 - 0.009 15.2 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pr_beta_C PF12465.3 EIW68638.1 - 0.22 10.8 3.9 0.49 9.6 2.7 1.6 1 0 0 1 1 1 0 Proteasome beta subunits C terminal UPF0014 PF03649.8 EIW68639.1 - 6.6e-40 136.8 11.2 8.6e-40 136.4 7.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) FtsX PF02687.16 EIW68639.1 - 0.12 12.1 20.8 0.021 14.5 3.4 3.1 2 1 1 3 3 3 0 FtsX-like permease family DUF1469 PF07332.6 EIW68639.1 - 4.3 7.0 7.8 5.6 6.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Galactosyl_T PF01762.16 EIW68641.1 - 5.6e-07 29.3 0.1 0.00023 20.8 0.0 3.0 2 1 1 3 3 3 2 Galactosyltransferase Fucose_iso_N2 PF07882.7 EIW68642.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Lac_bphage_repr PF06543.7 EIW68643.1 - 0.1 12.1 0.3 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Rib_5-P_isom_A PF06026.9 EIW68647.1 - 6.1e-51 172.1 0.0 7.8e-51 171.8 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) RNA_Me_trans PF04252.8 EIW68648.1 - 3.6e-38 130.9 0.0 4e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase HSP70 PF00012.15 EIW68651.1 - 1.3e-64 218.1 7.4 9.6e-52 175.7 0.0 2.9 3 0 0 3 3 3 2 Hsp70 protein PilM_2 PF11104.3 EIW68651.1 - 0.0072 15.2 0.0 0.029 13.2 0.0 2.0 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; DUF86 PF01934.12 EIW68651.1 - 0.042 13.4 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF86 Myc_N PF01056.13 EIW68651.1 - 7.4 5.6 7.1 15 4.6 4.9 1.4 1 0 0 1 1 1 0 Myc amino-terminal region EMP24_GP25L PF01105.19 EIW68652.1 - 1.2e-46 158.7 0.6 1.4e-46 158.5 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2846 PF11008.3 EIW68652.1 - 0.087 12.6 0.0 0.4 10.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2846) Septin PF00735.13 EIW68653.1 - 1.4e-108 362.1 0.2 1.7e-108 361.8 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIW68653.1 - 2.1e-08 34.0 0.0 9.6e-08 31.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW68653.1 - 9.4e-06 24.8 0.0 1.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIW68653.1 - 1.1e-05 24.6 0.0 2.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EIW68653.1 - 2e-05 24.4 0.8 0.062 13.1 0.3 2.6 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EIW68653.1 - 7.2e-05 22.2 0.2 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EIW68653.1 - 0.00018 21.0 0.0 0.00043 19.8 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EIW68653.1 - 0.0026 17.2 0.1 0.005 16.3 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 EIW68653.1 - 0.0031 16.4 0.1 0.0066 15.3 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EIW68653.1 - 0.0053 17.0 0.1 0.013 15.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 EIW68653.1 - 0.0078 16.7 0.0 0.022 15.2 0.0 1.8 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 EIW68653.1 - 0.01 15.9 0.0 0.036 14.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EIW68653.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain IIGP PF05049.8 EIW68653.1 - 0.012 14.4 0.4 0.039 12.7 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 EIW68653.1 - 0.016 16.0 1.6 1.3 9.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 EIW68653.1 - 0.038 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 EIW68653.1 - 0.043 13.1 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Ras family AAA_14 PF13173.1 EIW68653.1 - 0.048 13.5 1.9 0.27 11.1 0.0 2.8 3 1 0 3 3 2 0 AAA domain NB-ARC PF00931.17 EIW68653.1 - 0.048 12.4 0.5 0.073 11.9 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.12 EIW68653.1 - 0.057 13.2 0.3 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 Adeno_IVa2 PF02456.10 EIW68653.1 - 0.066 11.8 0.2 0.13 10.8 0.0 1.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_18 PF13238.1 EIW68653.1 - 0.079 13.2 0.2 3.1 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EIW68653.1 - 0.089 12.4 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EIW68653.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MSC PF09402.5 EIW68654.1 - 4.2e-70 236.0 0.0 6.2e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EIW68654.1 - 5.4e-14 51.4 0.0 1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain Cullin_binding PF03556.10 EIW68655.1 - 2.6e-32 111.4 0.0 4.2e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Cullin binding Adap_comp_sub PF00928.16 EIW68656.1 - 3.5e-20 72.1 0.0 4.9e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIW68656.1 - 8.6e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EIW68656.1 - 0.00041 19.6 0.0 0.00081 18.6 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain RRM_1 PF00076.17 EIW68657.1 - 6.4e-55 182.7 0.0 1.7e-19 69.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW68657.1 - 9.6e-42 140.8 0.0 8e-13 48.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW68657.1 - 2.4e-26 91.3 0.1 2.3e-10 40.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW68657.1 - 0.024 14.4 0.0 16 5.3 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DbpA PF03880.10 EIW68657.1 - 0.048 13.3 0.0 4.5 7.0 0.0 2.9 3 0 0 3 3 3 0 DbpA RNA binding domain Bromo_TP PF07524.8 EIW68658.1 - 1.7e-05 24.4 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated eIF-5a PF01287.15 EIW68659.1 - 1.8e-25 88.6 0.2 2.6e-25 88.1 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EIW68659.1 - 2.9e-05 23.5 0.8 5.8e-05 22.6 0.6 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EIW68659.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain CDC37_M PF08565.6 EIW68660.1 - 1.2e-42 145.3 0.1 1.2e-42 145.3 0.0 1.8 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.9 EIW68660.1 - 4.3e-41 141.1 15.8 5e-41 140.9 5.7 3.3 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_C PF08564.5 EIW68660.1 - 2.9e-23 81.6 2.9 8.1e-23 80.1 0.1 2.6 2 0 0 2 2 2 1 Cdc37 C terminal domain PP2C_C PF07830.8 EIW68660.1 - 0.0039 17.2 1.3 0.54 10.4 0.1 3.6 3 0 0 3 3 3 1 Protein serine/threonine phosphatase 2C, C-terminal domain DUF2072 PF09845.4 EIW68660.1 - 0.058 13.3 1.7 4.9 7.0 0.6 3.2 3 0 0 3 3 3 0 Zn-ribbon containing protein (DUF2072) SH3_9 PF14604.1 EIW68661.1 - 4e-31 106.3 2.2 1.8e-14 53.0 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EIW68661.1 - 3.6e-30 103.0 2.1 2.7e-17 61.8 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EIW68661.1 - 1.8e-22 78.5 0.2 8.1e-11 41.2 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 EIW68661.1 - 2.7e-08 33.7 0.0 6e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein NST1 PF13945.1 EIW68662.1 - 2.2e-28 99.6 0.0 2.2e-28 99.6 0.0 6.5 5 1 2 7 7 7 2 Salt tolerance down-regulator Amidase PF01425.16 EIW68663.1 - 1.7e-89 300.7 0.3 4.6e-89 299.2 0.2 1.6 1 1 0 1 1 1 1 Amidase Ank PF00023.25 EIW68663.1 - 0.088 12.6 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat RNase_PH PF01138.16 EIW68664.1 - 4.6e-14 52.8 0.1 9.2e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PS_Dcarbxylase PF02666.10 EIW68665.1 - 8.6e-54 181.9 0.0 1.3e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2462 PF09495.5 EIW68666.1 - 3.1e-18 66.2 10.1 3.4e-18 66.1 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) COG7 PF10191.4 EIW68666.1 - 0.043 11.7 0.0 0.052 11.4 0.0 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Astro_capsid PF03115.9 EIW68666.1 - 2 6.5 5.3 2 6.5 3.7 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RNase_PH PF01138.16 EIW68668.1 - 3e-28 98.7 0.0 4.1e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EIW68668.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF2013 PF09431.5 EIW68669.1 - 3.8e-45 153.0 0.6 4.5e-40 136.6 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2013) DUF3545 PF12065.3 EIW68669.1 - 0.61 9.8 2.4 0.76 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Tet_JBP PF12851.2 EIW68670.1 - 0.00036 19.8 0.0 0.00052 19.3 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Peptidase_M48 PF01435.13 EIW68672.1 - 1.2e-46 159.1 0.0 1.7e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 DUF955 PF06114.8 EIW68672.1 - 0.059 13.0 0.0 2.6 7.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF955) CLP_protease PF00574.18 EIW68673.1 - 1.8e-71 239.5 0.0 2.4e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Clp protease UCH_1 PF13423.1 EIW68674.1 - 1.7e-50 172.1 0.0 2.8e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EIW68674.1 - 2.4e-24 86.4 0.0 4e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EIW68674.1 - 8.2e-07 28.4 0.0 3.2e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Amidohydro_2 PF04909.9 EIW68676.1 - 0.0042 16.6 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 EIW68677.1 - 1.1e-26 93.3 33.2 2.7e-26 92.1 23.0 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3180 PF11377.3 EIW68677.1 - 1.5 8.6 6.5 1.6 8.5 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) DUF1604 PF07713.8 EIW68677.1 - 2.3 8.0 5.4 4.8 7.0 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) PITH PF06201.8 EIW68678.1 - 1.1e-40 138.8 0.0 1.5e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EIW68678.1 - 1.6e-24 85.6 0.0 2.6e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EIW68678.1 - 4.7e-05 22.9 0.0 8.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIW68678.1 - 5.9e-05 23.1 0.0 0.00026 21.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EIW68678.1 - 0.00027 21.0 0.1 0.002 18.2 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EIW68678.1 - 0.019 14.5 0.1 0.2 11.2 0.1 2.1 1 1 1 2 2 2 0 Redoxin Thioredoxin_7 PF13899.1 EIW68678.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.11 EIW68678.1 - 0.11 11.1 0.0 0.22 10.2 0.0 1.4 1 0 0 1 1 1 0 Phosducin KaiB PF07689.7 EIW68678.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 KaiB domain DEC-1_N PF04625.8 EIW68678.1 - 0.2 10.2 5.6 0.32 9.6 3.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1183 PF06682.7 EIW68679.1 - 1.3e-35 123.5 0.2 1.5e-35 123.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) RRM_1 PF00076.17 EIW68680.1 - 6.6e-59 195.4 0.0 3.2e-16 58.6 0.0 6.7 6 1 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW68680.1 - 1.7e-43 146.4 0.0 9.9e-11 41.4 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW68680.1 - 1.3e-16 60.1 0.0 4.7e-06 26.3 0.0 6.1 6 1 0 6 6 6 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW68680.1 - 0.14 11.9 0.0 15 5.4 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRN3 PF05327.6 EIW68680.1 - 1 7.3 3.1 1.7 6.6 2.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pantoate_ligase PF02569.10 EIW68682.1 - 6.3e-69 231.8 0.0 6.5e-41 139.9 0.0 2.2 1 1 0 2 2 2 2 Pantoate-beta-alanine ligase Podoplanin PF05808.6 EIW68683.1 - 9.6e-05 21.9 11.6 9.6e-05 21.9 8.0 2.3 1 1 1 2 2 2 1 Podoplanin DUF3609 PF12259.3 EIW68683.1 - 0.023 13.4 0.0 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Rifin_STEVOR PF02009.11 EIW68683.1 - 0.15 11.7 15.7 0.43 10.1 11.0 1.5 1 1 0 1 1 1 0 Rifin/stevor family MgsA_C PF12002.3 EIW68684.1 - 4.3e-54 182.7 0.0 6.6e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EIW68684.1 - 2.7e-15 56.7 0.0 5.9e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIW68684.1 - 8.8e-14 51.1 0.0 1.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIW68684.1 - 1e-06 28.9 1.0 0.0015 18.6 0.0 2.7 2 1 1 3 3 2 2 AAA domain AAA_16 PF13191.1 EIW68684.1 - 2.6e-06 27.5 0.3 0.00032 20.7 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EIW68684.1 - 2.8e-06 27.0 0.0 6.6e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EIW68684.1 - 0.00011 21.8 0.1 0.00029 20.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EIW68684.1 - 0.00014 21.8 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW68684.1 - 0.00028 21.6 0.0 0.00062 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EIW68684.1 - 0.00038 20.4 0.0 0.00086 19.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EIW68684.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW68684.1 - 0.0014 18.0 0.0 0.32 10.4 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 EIW68684.1 - 0.0016 18.7 0.1 0.0049 17.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EIW68684.1 - 0.0016 17.6 0.1 0.027 13.6 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EIW68684.1 - 0.005 16.3 0.1 0.17 11.3 0.0 2.7 2 1 1 3 3 3 1 AAA-like domain AAA_33 PF13671.1 EIW68684.1 - 0.0075 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW68684.1 - 0.0091 15.7 0.2 0.54 9.9 0.0 2.2 1 1 1 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 EIW68684.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EIW68684.1 - 0.02 15.1 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EIW68684.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 EIW68684.1 - 0.03 13.8 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EIW68684.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW68684.1 - 0.033 13.2 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EIW68684.1 - 0.035 13.5 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DNA_pol3_delta2 PF13177.1 EIW68684.1 - 0.043 13.4 0.0 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 DNA polymerase III, delta subunit AAA_30 PF13604.1 EIW68684.1 - 0.046 13.2 0.1 0.13 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EIW68684.1 - 0.048 12.3 0.0 0.16 10.6 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus SKI PF01202.17 EIW68684.1 - 0.05 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_13 PF13166.1 EIW68684.1 - 0.051 12.0 0.0 0.075 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIW68684.1 - 0.092 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EIW68684.1 - 0.16 11.8 0.1 13 5.5 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit zf-Di19 PF05605.7 EIW68684.1 - 0.16 12.0 0.1 0.37 10.9 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding cobW PF02492.14 EIW68684.1 - 0.17 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EIW68684.1 - 0.18 11.1 0.3 0.54 9.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain Chitin_synth_2 PF03142.10 EIW68685.1 - 6.4e-243 806.9 0.4 8.4e-243 806.5 0.3 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIW68685.1 - 6.4e-146 487.2 0.0 8.3e-146 486.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EIW68685.1 - 1.3e-17 63.3 0.0 5.5e-12 45.3 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EIW68685.1 - 2.9e-15 55.7 0.1 1.7e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EIW68685.1 - 1.8e-12 47.5 0.0 7.7e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIW68685.1 - 1.7e-11 44.2 7.0 1.7e-11 44.2 4.9 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EIW68685.1 - 2.6e-06 27.2 0.0 0.0038 16.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIW68685.1 - 0.00092 18.5 0.0 0.0054 16.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_30 PF13604.1 EIW68685.1 - 0.047 13.2 0.1 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIW68685.1 - 0.055 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RRM_1 PF00076.17 EIW68686.1 - 1.9e-11 43.4 0.0 2.6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW68686.1 - 5.6e-10 39.0 0.0 8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW68686.1 - 1.9e-08 33.9 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW68686.1 - 0.0034 17.1 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2183 PF09949.4 EIW68687.1 - 9.8e-25 86.4 0.0 2.2e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) UCH PF00443.24 EIW68688.1 - 3.3e-44 151.0 0.0 3.9e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW68688.1 - 2.7e-20 73.0 0.0 6.3e-20 71.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CbiC PF02570.10 EIW68688.1 - 0.12 11.7 0.2 0.33 10.3 0.1 1.7 2 0 0 2 2 2 0 Precorrin-8X methylmutase DEAD PF00270.24 EIW68689.1 - 3.4e-40 137.3 0.0 6.7e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW68689.1 - 6.9e-24 83.5 0.2 3.2e-23 81.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EIW68689.1 - 1.4e-17 63.2 0.1 2.5e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 EIW68689.1 - 0.0001 22.2 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C2H2_2 PF12756.2 EIW68690.1 - 1.6e-33 114.8 2.3 3.5e-26 91.2 0.0 3.4 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EIW68690.1 - 1.5e-13 50.4 3.7 3.3e-07 30.2 0.1 4.6 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW68690.1 - 9.5e-05 22.4 0.3 9.5e-05 22.4 0.2 3.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-LYAR PF08790.6 EIW68690.1 - 0.0017 18.0 4.5 1.1 8.9 0.2 3.5 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger FYDLN_acid PF09538.5 EIW68690.1 - 0.011 16.3 0.3 0.29 11.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_4 PF13894.1 EIW68690.1 - 0.021 15.1 12.1 0.097 13.0 0.2 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW68690.1 - 8.5 6.8 7.7 1.7e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-BED PF02892.10 EIW68690.1 - 9.8 6.0 6.5 6.5 6.5 0.0 3.5 3 0 0 3 3 3 0 BED zinc finger zf-C2H2 PF00096.21 EIW68691.1 - 1.5e-12 47.0 13.5 1.4e-06 28.2 2.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW68691.1 - 1.8e-10 40.5 5.1 1.8e-10 40.5 3.5 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW68691.1 - 4.8e-09 35.9 10.8 5.3e-05 23.2 1.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW68691.1 - 0.0002 21.1 1.8 0.00041 20.1 0.2 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger FYDLN_acid PF09538.5 EIW68691.1 - 0.00049 20.6 0.3 0.00067 20.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) zf-C2H2_jaz PF12171.3 EIW68691.1 - 0.00091 19.2 4.2 0.017 15.2 0.6 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EIW68691.1 - 0.0059 16.6 2.6 0.014 15.4 1.7 1.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 EIW68691.1 - 0.0099 15.8 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 1 zinc-finger NOA36 PF06524.7 EIW68691.1 - 0.037 13.2 0.2 0.042 13.1 0.2 1.1 1 0 0 1 1 1 0 NOA36 protein Rtf2 PF04641.7 EIW68691.1 - 0.042 13.0 0.1 0.049 12.8 0.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Zn-ribbon_8 PF09723.5 EIW68691.1 - 0.2 11.6 1.7 2.1 8.3 1.2 2.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 EIW68691.1 - 0.27 11.3 4.0 3.9 7.6 1.0 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EIW68691.1 - 3.2 8.1 5.2 8.3 6.7 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EIW68691.1 - 3.5 8.0 9.5 0.69 10.2 1.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain STE PF02200.11 EIW68692.1 - 1.2e-35 122.0 0.0 1.4e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 STE like transcription factor Pkinase PF00069.20 EIW68693.1 - 6.6e-72 241.7 0.1 8.8e-72 241.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW68693.1 - 2.4e-51 174.2 0.2 4.4e-51 173.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EIW68693.1 - 3.5e-23 81.7 0.0 1e-22 80.2 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EIW68693.1 - 7.2e-09 35.0 0.0 2.6e-08 33.1 0.0 1.8 1 1 1 2 2 2 1 Kinase-like PH PF00169.24 EIW68693.1 - 8.6e-07 29.1 0.1 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 PH domain APH PF01636.18 EIW68693.1 - 0.00034 20.4 0.6 0.008 15.9 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW68693.1 - 0.02 13.9 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family G_glu_transpept PF01019.16 EIW68696.1 - 2.6e-138 461.6 0.0 2.1e-137 458.7 0.0 1.9 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Aldedh PF00171.17 EIW68697.1 - 7.8e-155 515.7 0.0 9.2e-155 515.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EIW68697.1 - 0.04 13.1 0.0 0.075 12.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) zf-HC5HC2H_2 PF13832.1 EIW68698.1 - 6e-17 61.6 0.9 6e-17 61.6 0.6 4.6 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIW68698.1 - 1.8e-12 47.2 1.7 1.8e-12 47.2 1.2 4.9 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD PF00628.24 EIW68698.1 - 1.7e-11 43.5 51.9 2e-09 36.9 5.3 5.8 8 0 0 8 8 8 3 PHD-finger BAH PF01426.13 EIW68698.1 - 2.5e-10 40.1 0.0 6.8e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 BAH domain PHD_2 PF13831.1 EIW68698.1 - 5.7e-06 25.5 30.3 1.7e-05 24.0 2.1 5.1 5 0 0 5 5 5 3 PHD-finger C1_1 PF00130.17 EIW68698.1 - 7.2e-05 22.4 28.3 0.015 15.0 0.8 5.7 4 1 1 5 5 5 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EIW68698.1 - 0.00038 20.1 2.8 0.00038 20.1 2.0 5.9 7 0 0 7 7 7 2 Prokaryotic RING finger family 1 GATA PF00320.22 EIW68698.1 - 0.096 12.0 0.0 0.096 12.0 0.0 5.0 5 0 0 5 5 5 0 GATA zinc finger eIF2A PF08662.6 EIW68699.1 - 1e-25 90.5 0.0 1.9e-17 63.5 0.0 4.2 5 1 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 EIW68699.1 - 0.0018 18.2 0.0 0.0054 16.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW68699.1 - 0.002 17.7 0.0 0.0046 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW68699.1 - 0.002 17.9 0.0 0.0053 16.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EIW68699.1 - 0.0026 17.5 3.3 5.5 7.0 0.0 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat RE_MjaI PF09568.5 EIW68699.1 - 0.01 15.3 1.2 0.02 14.4 0.9 1.4 1 0 0 1 1 1 0 MjaI restriction endonuclease PD40 PF07676.7 EIW68699.1 - 0.059 13.0 0.6 0.44 10.2 0.0 2.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Glyco_trans_2_3 PF13632.1 EIW68700.1 - 3.8e-50 170.2 1.4 3.8e-50 170.2 1.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW68700.1 - 8.7e-09 35.5 0.0 3.2e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIW68700.1 - 0.00048 19.8 0.0 0.18 11.4 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIW68700.1 - 0.11 11.8 0.0 0.39 9.9 0.0 2.0 2 1 0 2 2 2 0 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EIW68701.1 - 5.4e-47 160.0 1.0 5.4e-47 160.0 0.7 2.5 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EIW68701.1 - 2.8e-05 23.4 0.0 9.9e-05 21.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EIW68701.1 - 0.0024 17.5 0.0 0.22 11.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Oxidored_FMN PF00724.15 EIW68702.1 - 6.5e-77 258.8 0.0 4.5e-69 233.0 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DUF663 PF04950.7 EIW68703.1 - 9.1e-97 323.5 0.0 3.4e-96 321.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EIW68703.1 - 3.3e-13 48.9 0.0 7.5e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain RNA_pol PF00940.14 EIW68704.1 - 2.1e-156 520.4 0.0 2.9e-156 520.0 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EIW68704.1 - 2.7e-78 263.4 0.1 4.3e-78 262.7 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Fungal_trans PF04082.13 EIW68705.1 - 1.7e-29 102.5 0.0 2.6e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW68705.1 - 1.7e-05 24.6 7.7 3.5e-05 23.6 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EIW68706.1 - 6.1e-70 235.3 0.0 7.1e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW68706.1 - 4.7e-48 163.5 0.0 6.8e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW68706.1 - 5.2e-07 28.9 0.0 2.1e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIW68706.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EIW68706.1 - 0.037 13.0 0.0 0.065 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ETF_alpha PF00766.14 EIW68707.1 - 1.2e-36 124.1 0.7 3.3e-36 122.7 0.5 1.8 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EIW68707.1 - 1.5e-35 122.3 0.5 2.7e-35 121.4 0.3 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TPR_11 PF13414.1 EIW68708.1 - 8.4e-09 34.9 0.0 1.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EIW68708.1 - 2.5e-06 26.9 0.4 0.15 12.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW68708.1 - 0.00026 20.4 0.0 0.094 12.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW68708.1 - 0.016 15.8 2.2 1.5 9.6 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat CAP_N PF01213.14 EIW68708.1 - 0.073 12.3 0.9 0.099 11.9 0.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TPR_19 PF14559.1 EIW68708.1 - 0.082 13.2 0.0 9.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIW68708.1 - 0.44 11.2 5.7 19 6.0 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ThiF PF00899.16 EIW68710.1 - 1.4e-32 112.3 0.0 2.4e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EIW68710.1 - 0.0058 16.7 0.3 0.022 14.8 0.0 2.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Myosin_head PF00063.16 EIW68711.1 - 4.9e-236 785.0 0.2 1e-235 783.9 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EIW68711.1 - 4.1e-34 116.6 3.0 1.3e-33 115.0 2.1 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EIW68711.1 - 7.7e-19 65.4 33.3 7e-05 22.1 0.4 7.0 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 EIW68711.1 - 0.0074 16.4 0.0 0.056 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain IFT57 PF10498.4 EIW68711.1 - 0.019 13.7 12.5 0.044 12.5 8.6 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.5 EIW68711.1 - 0.042 13.9 9.6 0.041 13.9 4.0 2.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_19 PF13245.1 EIW68711.1 - 0.061 13.0 0.3 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain DivIC PF04977.10 EIW68711.1 - 1.1 8.7 18.4 0.72 9.3 0.9 3.4 3 0 0 3 3 3 0 Septum formation initiator DUF342 PF03961.8 EIW68711.1 - 9.6 4.4 9.4 17 3.6 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BTB PF00651.26 EIW68712.1 - 1e-12 47.9 0.0 3.9e-10 39.7 0.0 3.2 3 0 0 3 3 3 1 BTB/POZ domain CAP_GLY PF01302.20 EIW68712.1 - 3.9e-05 23.2 0.0 8.8e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 CAP-Gly domain Ndc80_HEC PF03801.8 EIW68713.1 - 4e-40 136.8 0.1 1e-39 135.5 0.0 1.7 2 0 0 2 2 2 1 HEC/Ndc80p family Reo_sigmaC PF04582.7 EIW68713.1 - 0.78 8.8 9.3 1.5 7.9 0.1 2.8 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Sec20 PF03908.8 EIW68713.1 - 4.2 7.1 11.7 0.52 10.0 0.6 3.7 3 1 0 3 3 3 0 Sec20 TAP42 PF04177.7 EIW68715.1 - 4.2e-55 187.0 0.0 4.8e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family PCI PF01399.22 EIW68716.1 - 2.5e-16 59.8 0.7 8.3e-16 58.2 0.5 2.0 1 0 0 1 1 1 1 PCI domain Peptidase_S28 PF05577.7 EIW68716.1 - 0.0061 15.1 0.0 0.0098 14.5 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 TPR_12 PF13424.1 EIW68716.1 - 0.61 10.0 7.0 8.8 6.3 1.4 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW68716.1 - 2.1 9.1 6.3 11 6.9 0.6 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Vps26 PF03643.10 EIW68717.1 - 4.5e-127 422.5 7.3 5.3e-127 422.2 5.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EIW68717.1 - 0.0039 17.0 1.9 0.63 9.8 0.2 3.5 2 1 2 4 4 4 1 Arrestin (or S-antigen), N-terminal domain TM1506 PF08973.5 EIW68717.1 - 0.081 12.4 0.2 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1893) Pkinase PF00069.20 EIW68718.1 - 9.2e-40 136.4 0.0 6.4e-29 100.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW68718.1 - 1.8e-23 82.9 0.0 2.5e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIW68718.1 - 0.093 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pyridoxal_deC PF00282.14 EIW68719.1 - 1.4e-37 129.0 0.0 1.8e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SLA_LP_auto_ag PF05889.8 EIW68719.1 - 0.0003 19.3 0.0 0.0027 16.2 0.0 2.0 2 0 0 2 2 2 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_5 PF00266.14 EIW68719.1 - 0.027 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.16 EIW68719.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Membr_traf_MHD PF10540.4 EIW68721.1 - 9.5e-20 70.7 1.0 2.5e-19 69.4 0.1 2.2 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EIW68721.1 - 5.9e-08 32.4 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain Fungal_trans PF04082.13 EIW68722.1 - 4.3e-09 35.6 0.0 8.5e-09 34.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW68722.1 - 6.2e-05 22.8 9.0 0.001 18.9 3.5 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L39 PF00832.15 EIW68723.1 - 7.7e-24 82.8 8.0 8.6e-24 82.7 5.5 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Rad21_Rec8_N PF04825.8 EIW68724.1 - 3.5e-35 120.3 0.0 5.3e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EIW68724.1 - 1e-11 43.8 0.1 2.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EIW68724.1 - 0.0026 17.4 0.0 0.0067 16.0 0.0 1.7 1 0 0 1 1 1 1 ScpA/B protein PMT PF02366.13 EIW68726.1 - 2.7e-78 262.7 16.8 2.7e-78 262.7 11.6 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIW68726.1 - 3.1e-20 72.5 3.1 1.3e-19 70.4 0.8 2.1 1 1 1 2 2 2 2 MIR domain MTP18 PF10558.4 EIW68727.1 - 6e-57 191.7 1.3 7.2e-57 191.4 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Syntaxin-6_N PF09177.6 EIW68729.1 - 1.6e-19 70.0 0.8 3e-19 69.2 0.2 1.6 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EIW68729.1 - 1.6e-11 43.7 2.6 2.6e-11 43.0 0.6 2.2 2 1 1 3 3 3 1 SNARE domain DUF2077 PF09850.4 EIW68729.1 - 0.0053 16.1 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2077) V-SNARE_C PF12352.3 EIW68729.1 - 0.033 14.2 1.7 0.64 10.1 0.5 2.5 1 1 1 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF3782 PF12644.2 EIW68729.1 - 0.065 13.0 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) DUF4164 PF13747.1 EIW68729.1 - 0.072 13.2 2.5 0.17 12.0 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TBPIP PF07106.8 EIW68729.1 - 0.11 12.0 0.1 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF883 PF05957.8 EIW68729.1 - 0.63 10.4 2.9 1.9 8.9 0.2 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) MATH PF00917.21 EIW68730.1 - 2.3e-05 24.5 0.2 5.1e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 MATH domain Slx4 PF09494.5 EIW68731.1 - 1.3e-10 40.8 0.0 2.9e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease NAD_binding_6 PF08030.7 EIW68732.1 - 9.8e-37 126.2 0.0 1.4e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIW68732.1 - 3.3e-23 81.5 0.0 1.2e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EIW68732.1 - 1.1e-12 48.1 11.9 1.1e-12 48.1 8.2 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EIW68732.1 - 0.0034 17.4 0.0 0.0077 16.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIW68732.1 - 0.028 14.9 0.0 0.42 11.2 0.0 2.3 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain WD40 PF00400.27 EIW68733.1 - 2e-53 176.4 10.9 3e-10 39.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW68733.1 - 7.1e-05 21.1 0.0 0.05 11.7 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW68733.1 - 0.0013 17.6 0.2 0.03 13.0 0.0 2.6 1 1 1 2 2 2 1 Nup133 N terminal like DUF3312 PF11768.3 EIW68733.1 - 0.0032 15.7 0.0 0.016 13.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) WD40 PF00400.27 EIW68734.1 - 1.7e-12 46.7 18.1 6.3e-05 22.7 0.2 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat zf-rbx1 PF12678.2 EIW68734.1 - 0.13 12.3 10.0 0.28 11.3 7.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EIW68734.1 - 0.92 9.3 12.4 2 8.3 8.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger NADH_B2 PF14813.1 EIW68735.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 GTP_EFTU PF00009.22 EIW68736.1 - 3.6e-36 124.3 0.0 5.6e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EIW68736.1 - 1.8e-33 114.4 0.1 4.6e-33 113.1 0.1 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EIW68736.1 - 4e-09 36.4 0.1 1.3e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SNF2_N PF00176.18 EIW68737.1 - 2.7e-43 147.8 0.0 1.6e-42 145.3 0.0 2.3 3 1 0 3 3 3 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 EIW68737.1 - 7.6e-09 35.1 6.8 1.3e-08 34.3 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW68737.1 - 8e-08 31.9 9.2 1.6e-07 31.0 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EIW68737.1 - 6.7e-07 28.9 8.7 1.3e-06 27.9 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW68737.1 - 1.6e-06 28.0 8.7 3e-06 27.1 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EIW68737.1 - 0.00068 19.1 5.8 0.0014 18.1 4.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 EIW68737.1 - 0.00072 19.1 7.7 0.0014 18.2 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW68737.1 - 0.003 17.4 7.6 0.0061 16.4 5.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EIW68737.1 - 0.011 15.3 4.3 0.021 14.3 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EIW68737.1 - 0.019 14.6 3.8 0.049 13.3 2.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Baculo_IE-1 PF05290.6 EIW68737.1 - 0.076 12.7 0.1 0.26 11.0 0.1 1.9 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 EIW68737.1 - 0.22 11.6 5.1 0.5 10.5 3.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 EIW68737.1 - 0.24 11.2 1.7 0.52 10.1 1.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EIW68737.1 - 0.43 10.4 3.3 1 9.2 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EIW68737.1 - 1.2 9.0 3.4 2.8 7.8 2.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon RhoGEF PF00621.15 EIW68738.1 - 2.2e-20 73.2 0.0 3.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Glutaredoxin PF00462.19 EIW68739.1 - 2.6e-16 59.3 0.0 3.6e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.1 EIW68739.1 - 3.2e-05 23.8 0.2 0.00016 21.6 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EIW68739.1 - 0.00023 20.7 0.0 0.00026 20.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EIW68739.1 - 0.00028 21.0 0.1 0.00034 20.7 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.1 EIW68739.1 - 0.00065 19.8 0.0 0.00084 19.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 EIW68739.1 - 0.00067 19.8 0.0 0.00075 19.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DUF953 PF06110.6 EIW68739.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.1 EIW68739.1 - 0.0022 17.7 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin PF00085.15 EIW68739.1 - 0.0087 15.7 0.2 0.009 15.6 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIW68739.1 - 0.013 15.5 0.1 0.023 14.8 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like DUF2730 PF10805.3 EIW68740.1 - 0.0034 17.0 0.5 0.025 14.3 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2730) DUF4613 PF15390.1 EIW68740.1 - 5.5 5.0 10.6 0.47 8.5 3.8 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4613) Peptidase_C12 PF01088.16 EIW68741.1 - 5.3e-58 195.7 0.0 6.7e-58 195.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ATP_sub_h PF10775.4 EIW68742.1 - 1.3e-20 72.9 0.4 1.8e-20 72.4 0.2 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EIW68742.1 - 0.019 14.8 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 ARID PF01388.16 EIW68743.1 - 2.4e-05 24.0 0.0 5.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C2H2_4 PF13894.1 EIW68743.1 - 0.00021 21.3 11.1 0.043 14.1 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW68743.1 - 0.028 14.7 7.3 1.5 9.3 0.1 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type AT_hook PF02178.14 EIW68743.1 - 3.3 7.6 13.4 3.1 7.7 0.3 3.4 2 0 0 2 2 2 0 AT hook motif Ish1 PF10281.4 EIW68744.1 - 4.2e-46 154.6 27.9 9.4e-10 38.3 0.0 8.5 9 0 0 9 9 9 6 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EIW68744.1 - 0.00014 21.3 0.0 5.4 6.6 0.0 4.6 4 0 0 4 4 4 2 HeH/LEM domain GYF PF02213.11 EIW68744.1 - 0.049 13.2 1.9 1.2 8.7 0.0 3.2 3 0 0 3 3 3 0 GYF domain TilS PF09179.6 EIW68744.1 - 0.11 12.5 2.6 24 5.0 0.1 4.2 5 0 0 5 5 5 0 TilS substrate binding domain TryThrA_C PF12319.3 EIW68744.1 - 0.38 9.9 20.5 0.45 9.6 8.3 3.8 2 1 2 4 4 4 0 Tryptophan-Threonine-rich plasmodium antigen C terminal NHase_alpha PF02979.11 EIW68744.1 - 1.7 7.9 4.6 3.1 7.0 0.1 3.2 3 1 1 4 4 4 0 Nitrile hydratase, alpha chain FAD_binding_1 PF00667.15 EIW68745.1 - 8.6e-56 188.8 0.0 1.8e-55 187.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EIW68745.1 - 5.4e-31 107.5 0.4 1.2e-30 106.4 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EIW68745.1 - 7e-18 65.1 0.0 2.5e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF1295 PF06966.7 EIW68746.1 - 7e-51 172.7 0.3 9.9e-51 172.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EIW68746.1 - 0.004 17.2 0.0 0.004 17.2 0.0 3.2 4 0 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.9 EIW68746.1 - 0.037 14.2 2.1 0.042 14.0 0.1 2.2 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 EIW68746.1 - 0.24 11.1 3.0 0.4 10.4 0.0 2.7 3 0 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase Nucleoporin_C PF03177.9 EIW68747.1 - 5.5e-83 279.4 1.4 7.3e-83 279.0 1.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EIW68747.1 - 7.8e-53 179.7 0.2 1.1e-52 179.2 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Myb_DNA-bind_2 PF08914.6 EIW68748.1 - 0.0026 17.5 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Rap1 Myb domain DUF92 PF01940.11 EIW68749.1 - 3e-56 190.1 1.8 3.5e-56 189.9 1.3 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF1469 PF07332.6 EIW68749.1 - 3 7.6 6.7 0.65 9.7 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Mago_nashi PF02792.9 EIW68750.1 - 5.5e-68 227.1 0.4 6.7e-68 226.8 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Omega_Repress PF07764.6 EIW68750.1 - 0.028 14.7 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Omega Transcriptional Repressor COQ7 PF03232.8 EIW68751.1 - 3.1e-61 205.8 0.0 4e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 AOX PF01786.12 EIW68751.1 - 0.022 14.1 0.0 0.038 13.4 0.0 1.3 1 1 0 1 1 1 0 Alternative oxidase HMGL-like PF00682.14 EIW68752.1 - 3.2e-71 239.7 0.4 4.9e-71 239.1 0.3 1.3 1 0 0 1 1 1 1 HMGL-like DUF4646 PF15496.1 EIW68753.1 - 0.003 17.5 0.1 0.18 11.8 0.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF4603 PF15376.1 EIW68753.1 - 1.7 5.7 3.7 2.1 5.4 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) PLU-1 PF08429.6 EIW68754.1 - 1.8e-68 230.9 6.8 2.5e-68 230.4 4.7 1.2 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.17 EIW68754.1 - 6.2e-38 129.5 0.9 1.3e-37 128.5 0.6 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EIW68754.1 - 1.4e-17 63.3 0.1 5.7e-17 61.3 0.0 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 EIW68754.1 - 3.6e-15 55.7 9.8 1.3e-14 53.9 6.8 2.1 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 EIW68754.1 - 8.4e-15 54.2 59.0 4.7e-10 38.9 4.8 4.7 4 1 1 5 5 5 3 PHD-finger JmjN PF02375.12 EIW68754.1 - 1.8e-14 52.9 0.7 3.7e-14 51.9 0.5 1.6 1 0 0 1 1 1 1 jmjN domain priB_priC PF07445.7 EIW68754.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Primosomal replication protein priB and priC PHD_2 PF13831.1 EIW68754.1 - 0.95 8.8 31.4 0.46 9.8 1.8 3.6 3 0 0 3 3 3 0 PHD-finger RhoGEF PF00621.15 EIW68755.1 - 1.4e-15 57.6 0.0 2.3e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PAP_assoc PF03828.14 EIW68756.1 - 1.3e-19 69.8 0.1 2.5e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EIW68756.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain PAP_central PF04928.12 EIW68756.1 - 0.013 14.2 0.0 3.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Poly(A) polymerase central domain Pyr_redox_dim PF02852.17 EIW68757.1 - 1.3e-42 144.3 0.3 4e-42 142.7 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EIW68757.1 - 1.4e-37 129.5 18.0 7.3e-36 123.9 11.3 3.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW68757.1 - 4.7e-20 71.7 11.4 3.5e-18 65.7 2.2 3.6 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW68757.1 - 1.8e-14 54.2 0.1 2.7e-08 34.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW68757.1 - 1.4e-11 44.1 8.8 4.8e-10 39.0 0.1 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 EIW68757.1 - 6e-10 38.5 0.4 6e-10 38.5 0.3 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EIW68757.1 - 1.7e-07 30.5 0.7 0.014 14.3 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EIW68757.1 - 9.7e-07 28.1 8.8 5.6e-05 22.3 0.1 2.6 1 1 1 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 EIW68757.1 - 1.8e-06 27.2 10.5 0.026 13.6 0.0 3.4 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EIW68757.1 - 4.8e-06 26.5 8.1 0.00016 21.6 0.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW68757.1 - 9.8e-06 24.6 1.7 9.8e-06 24.6 1.2 4.0 3 1 1 4 4 4 1 FAD binding domain HI0933_like PF03486.9 EIW68757.1 - 1.2e-05 24.0 15.5 0.00033 19.2 0.6 4.1 3 1 1 4 4 4 2 HI0933-like protein DAO PF01266.19 EIW68757.1 - 0.00019 20.4 20.9 0.0085 15.0 0.7 3.7 2 2 2 4 4 4 3 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EIW68757.1 - 0.00035 20.1 2.2 0.044 13.3 0.2 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.14 EIW68757.1 - 0.00046 19.3 1.0 0.0033 16.5 0.6 2.5 3 1 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.7 EIW68757.1 - 0.01 14.7 2.4 0.26 10.1 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EIW68757.1 - 0.33 10.7 1.5 18 5.0 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EIW68757.1 - 0.39 11.0 5.2 11 6.3 1.6 3.7 3 1 0 3 3 3 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EIW68757.1 - 6.9 6.2 7.4 0.8 9.3 1.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XPG_N PF00752.12 EIW68761.1 - 1.3e-32 112.0 0.0 2.5e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EIW68761.1 - 1e-28 99.1 0.0 2.3e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EIW68761.1 - 2.9e-06 27.4 0.0 9.4e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Sod_Cu PF00080.15 EIW68762.1 - 4.4e-48 163.0 7.2 5.1e-48 162.8 5.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.7 EIW68762.1 - 0.014 15.9 0.9 1.6 9.3 0.1 2.2 1 1 1 2 2 2 0 CHRD domain HisG PF01634.13 EIW68763.1 - 7.4e-45 152.4 0.0 1.1e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EIW68763.1 - 1.6e-25 88.7 0.0 3e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain SH3_1 PF00018.23 EIW68764.1 - 6.7e-06 25.3 0.1 1.5e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW68764.1 - 1.9e-05 24.1 0.1 3.7e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW68764.1 - 0.034 13.6 0.2 0.081 12.4 0.1 1.7 1 0 0 1 1 1 0 Variant SH3 domain zf-C2H2 PF00096.21 EIW68766.1 - 3.9e-07 30.0 12.1 0.00023 21.3 0.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW68766.1 - 0.00012 22.1 10.8 0.014 15.6 2.6 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW68766.1 - 0.00025 21.1 10.6 0.012 15.9 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW68766.1 - 0.091 12.9 0.5 0.091 12.9 0.3 3.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding UPF0029 PF01205.14 EIW68768.1 - 2.1e-26 91.7 0.0 3.9e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EIW68768.1 - 0.00022 21.0 0.9 0.0007 19.4 0.1 2.3 2 1 0 2 2 2 1 RWD domain DUF676 PF05057.9 EIW68769.1 - 6.4e-37 126.9 0.0 8.2e-36 123.3 0.0 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EIW68769.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DnaJ PF00226.26 EIW68771.1 - 1.3e-15 56.8 0.0 3.5e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain LZ_Tnp_IS66 PF13007.2 EIW68771.1 - 0.016 15.8 0.8 0.031 14.9 0.6 1.4 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain Cellulase PF00150.13 EIW68772.1 - 2.6e-15 56.3 1.8 3.7e-15 55.8 1.2 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EIW68772.1 - 0.035 14.5 0.0 0.25 11.8 0.0 2.3 2 0 0 2 2 2 0 Sugar-binding cellulase-like adh_short_C2 PF13561.1 EIW68773.1 - 2.3e-25 89.7 0.0 3.7e-25 89.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW68773.1 - 1.2e-24 87.0 0.1 1.5e-23 83.5 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EIW68773.1 - 1.1e-08 34.7 0.0 2e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EIW68773.1 - 3.9e-05 23.4 0.0 0.091 12.4 0.0 2.2 1 1 1 2 2 2 2 KR domain DapB_N PF01113.15 EIW68773.1 - 0.0032 17.3 0.0 0.026 14.4 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 EIW68773.1 - 0.0033 17.4 0.1 0.0062 16.5 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIW68773.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.10 EIW68773.1 - 0.028 14.0 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3Beta_HSD PF01073.14 EIW68773.1 - 0.037 12.7 0.0 0.068 11.8 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3842 PF12953.2 EIW68773.1 - 0.051 13.7 0.2 0.09 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) FtsJ PF01728.14 EIW68773.1 - 0.054 13.4 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase NAD_binding_4 PF07993.7 EIW68773.1 - 0.065 12.1 0.0 8.6 5.1 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein TrkA_N PF02254.13 EIW68773.1 - 0.075 13.0 0.1 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain HEAT_EZ PF13513.1 EIW68774.1 - 8.8e-12 45.1 29.3 3.2e-09 36.9 0.1 9.7 9 2 2 11 11 11 2 HEAT-like repeat IBN_N PF03810.14 EIW68774.1 - 2.1e-09 37.1 1.4 4.5e-08 32.8 0.2 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EIW68774.1 - 6.2e-08 32.8 20.3 0.0025 18.0 0.1 7.1 5 2 2 7 7 7 4 HEAT repeats HEAT PF02985.17 EIW68774.1 - 1.1e-06 28.2 19.2 0.84 9.8 0.0 9.6 10 0 0 10 10 10 2 HEAT repeat RIX1 PF08167.7 EIW68774.1 - 1.3e-05 24.9 1.8 0.042 13.5 0.0 5.0 4 2 1 6 6 6 1 rRNA processing/ribosome biogenesis DUF3385 PF11865.3 EIW68774.1 - 0.00044 20.2 0.1 40 4.0 0.0 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) Arm PF00514.18 EIW68774.1 - 0.00075 19.2 8.8 0.81 9.6 0.0 5.7 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 EIW68774.1 - 0.0055 15.0 0.1 2 6.5 0.1 2.3 1 1 1 2 2 2 2 Proteasome non-ATPase 26S subunit RNA_pol_Rpc4 PF05132.9 EIW68775.1 - 0.091 12.7 2.4 0.1 12.6 0.7 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 Cu_bind_like PF02298.12 EIW68776.1 - 0.16 11.7 0.3 0.47 10.2 0.2 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain OppC_N PF12911.2 EIW68777.1 - 0.062 12.6 0.8 0.18 11.1 0.5 1.8 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Utp14 PF04615.8 EIW68777.1 - 1.7 6.7 5.8 2.6 6.1 4.0 1.3 1 0 0 1 1 1 0 Utp14 protein Rifin_STEVOR PF02009.11 EIW68777.1 - 3.1 7.3 4.1 18 4.8 2.9 2.0 1 1 0 1 1 1 0 Rifin/stevor family ADK PF00406.17 EIW68778.1 - 1.5e-34 119.0 0.0 1.7e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EIW68778.1 - 5e-11 42.0 0.0 7.7e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EIW68778.1 - 0.007 17.1 0.0 0.01 16.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW68778.1 - 0.048 13.9 0.0 0.074 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EIW68779.1 - 6.4e-20 70.2 16.6 0.0011 18.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIW68779.1 - 0.00026 20.7 0.0 0.048 13.3 0.0 3.0 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EIW68779.1 - 0.17 10.6 0.0 0.46 9.2 0.0 1.8 2 0 0 2 2 2 0 Coatomer WD associated region zf-CCHC PF00098.18 EIW68781.1 - 0.0025 17.6 1.9 0.0044 16.8 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW68781.1 - 0.06 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Resolvase PF00239.16 EIW68783.1 - 0.0066 16.3 1.7 0.011 15.5 1.2 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC_2 PF13696.1 EIW68783.1 - 0.037 13.5 0.2 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIW68783.1 - 0.44 10.5 4.0 0.71 9.9 2.8 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF2587 PF10759.4 EIW68785.1 - 0.032 13.6 0.1 0.086 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW68786.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW68786.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW68786.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3996 PF13161.1 EIW68788.1 - 0.008 15.8 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3996) DDE_1 PF03184.14 EIW68789.1 - 1.5e-39 135.3 0.0 1.3e-38 132.3 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EIW68789.1 - 0.00068 19.1 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain GntR PF00392.16 EIW68789.1 - 0.0019 17.5 1.4 0.17 11.3 0.0 3.1 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_Tnp_Tc5 PF03221.11 EIW68789.1 - 0.0029 17.3 0.0 0.0083 15.9 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CP12 PF02672.10 EIW68789.1 - 2.3 8.7 5.6 0.25 11.8 0.7 1.8 2 0 0 2 2 2 0 CP12 domain zf-UBP PF02148.14 EIW68791.1 - 2.2 8.4 6.6 4.6 7.4 4.6 1.7 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein NAD_binding_6 PF08030.7 EIW68792.1 - 2.2e-17 63.3 0.0 3.1e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EIW68792.1 - 1.2e-15 57.7 9.3 1.2e-15 57.7 6.5 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIW68792.1 - 7.7e-14 51.4 0.0 7.9e-07 28.9 0.0 2.7 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EIW68792.1 - 0.0033 17.9 0.1 0.019 15.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Ctr PF04145.10 EIW68793.1 - 2.7e-30 105.3 2.2 3.3e-30 105.0 1.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF2069 PF09842.4 EIW68793.1 - 0.069 13.1 0.8 0.19 11.7 0.2 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) OAD_gamma PF04277.8 EIW68793.1 - 2.1 8.7 4.0 4 7.8 2.8 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain AdoHcyase PF05221.12 EIW68794.1 - 4e-140 465.3 0.0 4.5e-140 465.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EIW68794.1 - 9.3e-85 282.4 1.5 1.4e-84 281.8 1.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EIW68794.1 - 3.1e-08 32.9 0.0 6.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EIW68794.1 - 3.7e-05 23.1 0.1 6.4e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EIW68794.1 - 7e-05 22.8 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain TMEM107 PF14995.1 EIW68794.1 - 0.027 14.5 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein ELFV_dehydrog PF00208.16 EIW68794.1 - 0.055 13.0 0.1 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Exo70 PF03081.10 EIW68795.1 - 2.5e-37 128.5 0.0 4.9e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit COG6 PF06419.6 EIW68795.1 - 0.056 11.5 0.0 0.089 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 LuxC PF05893.9 EIW68795.1 - 0.28 9.8 0.0 0.48 9.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DivIC PF04977.10 EIW68799.1 - 0.017 14.6 0.1 0.088 12.3 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 EIW68800.1 - 1.7e-09 37.4 10.1 3.7e-09 36.4 3.0 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EIW68800.1 - 2.4e-09 36.8 7.8 2.4e-09 36.8 5.4 2.4 2 0 0 2 2 2 1 Basic region leucine zipper HAP1_N PF04849.8 EIW68800.1 - 0.02 13.8 1.3 0.024 13.5 0.1 1.6 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Mannosyl_trans3 PF11051.3 EIW68801.1 - 1.6e-40 139.1 0.0 5.5e-40 137.4 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative SSB PF00436.20 EIW68802.1 - 0.035 13.9 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Single-strand binding protein family Ras PF00071.17 EIW68803.1 - 4.6e-48 162.6 0.0 6.5e-48 162.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW68803.1 - 1.2e-17 64.4 0.0 1.8e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW68803.1 - 7.4e-16 57.8 0.0 1.5e-15 56.8 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW68803.1 - 1.5e-06 27.8 0.0 3.7e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW68803.1 - 1.4e-05 24.9 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EIW68803.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-H2C2 PF09337.5 EIW68804.1 - 0.0088 15.4 3.0 0.018 14.4 2.1 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Mucin PF01456.12 EIW68804.1 - 6.1 6.6 8.6 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Gemini_BL1 PF00845.14 EIW68805.1 - 0.039 13.3 0.4 0.055 12.8 0.3 1.4 1 1 0 1 1 1 0 Geminivirus BL1 movement protein Nol1_Nop2_Fmu PF01189.12 EIW68806.1 - 5.7e-33 114.5 0.0 5.7e-31 107.9 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EIW68806.1 - 0.057 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FAM74 PF15026.1 EIW68806.1 - 0.08 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 FAM74 protein DUF3117 PF11314.3 EIW68806.1 - 0.08 12.4 0.2 0.36 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3117) FtsJ PF01728.14 EIW68806.1 - 0.081 12.9 0.0 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Helicase_C PF00271.26 EIW68807.1 - 5.6e-16 58.1 0.0 6.6e-13 48.3 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EIW68807.1 - 7.6e-12 45.0 0.0 2.1e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.5 EIW68807.1 - 0.0053 16.4 0.1 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 RQC domain DUF972 PF06156.8 EIW68807.1 - 0.0085 16.4 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF972) SecA_DEAD PF07517.9 EIW68807.1 - 0.046 12.9 0.0 0.091 12.0 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain ABC_membrane PF00664.18 EIW68809.1 - 5.5e-45 153.9 1.5 7e-45 153.5 1.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EIW68809.1 - 1.4e-33 116.0 0.0 3.5e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EIW68809.1 - 1.5e-05 24.3 0.0 0.0017 17.6 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 EIW68809.1 - 0.00015 20.9 0.0 0.00031 19.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_21 PF13304.1 EIW68809.1 - 0.00029 20.8 0.0 0.76 9.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIW68809.1 - 0.0039 17.1 1.2 0.029 14.3 0.9 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW68809.1 - 0.0069 16.5 0.1 0.032 14.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 EIW68809.1 - 0.018 13.6 0.1 0.03 12.9 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.20 EIW68809.1 - 0.022 14.2 0.2 4.8 6.6 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 EIW68809.1 - 0.024 14.8 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EIW68809.1 - 0.038 13.5 0.1 0.092 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 EIW68809.1 - 0.058 12.8 0.0 0.53 9.7 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase Sybindin PF04099.7 EIW68810.1 - 6.4e-36 123.1 0.0 7.1e-36 123.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EIW68810.1 - 4.7e-07 29.7 0.0 5.5e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region SKN1 PF03935.10 EIW68811.1 - 9.8e-178 591.3 11.4 1.2e-177 591.0 7.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) EF-hand_1 PF00036.27 EIW68813.1 - 6.2e-30 100.2 11.7 1.8e-07 29.9 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIW68813.1 - 4.2e-27 94.0 2.8 3.2e-13 49.6 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EIW68813.1 - 1.4e-23 81.1 13.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EIW68813.1 - 3.4e-22 76.2 8.4 6.9e-06 25.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EIW68813.1 - 2.4e-16 59.0 15.1 9.4e-08 31.5 1.0 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EIW68813.1 - 1.5e-05 24.9 0.0 0.0051 16.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EIW68813.1 - 5.2e-05 22.9 5.0 0.0039 16.9 0.5 3.5 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EIW68813.1 - 0.0012 18.7 0.1 0.28 11.1 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain DUF221 PF02714.10 EIW68814.1 - 1.1e-107 359.7 18.4 1.7e-107 359.0 12.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIW68814.1 - 4.2e-32 110.8 2.2 4.2e-32 110.8 1.5 2.6 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIW68814.1 - 1.3e-07 32.0 0.0 2.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EIW68814.1 - 0.015 15.2 0.1 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATP-synt_Eps PF04627.8 EIW68815.1 - 1.2e-22 79.1 1.4 1.4e-22 79.0 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Pneumo_matrix PF03393.11 EIW68817.1 - 0.071 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Pneumovirus matrix protein zf-CCHC PF00098.18 EIW68819.1 - 0.0081 16.0 3.0 0.016 15.1 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle DAGK_prokar PF01219.14 EIW68820.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase DUF4588 PF15251.1 EIW68822.1 - 0.0047 16.9 1.8 0.014 15.3 1.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Retrotrans_gag PF03732.12 EIW68824.1 - 2.2e-05 24.4 0.0 4.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIW68824.1 - 0.002 17.9 1.9 0.0037 17.1 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4 PF00097.20 EIW68826.1 - 1.2e-06 28.0 5.6 2e-06 27.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW68826.1 - 1.4e-06 28.2 8.3 2.3e-06 27.5 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW68826.1 - 1.1e-05 25.0 6.1 1.7e-05 24.3 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW68826.1 - 2.4e-05 24.0 7.5 3.9e-05 23.4 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EIW68826.1 - 0.0023 17.6 5.6 0.0039 16.8 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIW68826.1 - 0.0055 16.5 7.2 0.009 15.8 5.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EIW68826.1 - 0.071 12.6 7.2 0.43 10.1 5.0 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EIW68826.1 - 1 9.0 4.5 2 8.0 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EIW68826.1 - 2.2 7.8 5.9 4.7 6.8 4.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger HSF_DNA-bind PF00447.12 EIW68827.1 - 8.2e-18 64.4 0.0 3.4e-17 62.4 0.0 2.2 1 0 0 1 1 1 1 HSF-type DNA-binding zf-DHHC PF01529.15 EIW68828.1 - 3.5e-13 49.3 18.2 1e-11 44.5 7.9 3.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF2457 PF10446.4 EIW68828.1 - 1.8 7.1 10.9 3.6 6.2 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cnd2 PF05786.9 EIW68829.1 - 3.5e-144 482.0 0.0 5e-144 481.5 0.0 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 PI3K_1B_p101 PF10486.4 EIW68831.1 - 1.5 6.3 4.2 2.2 5.7 2.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.7 EIW68831.1 - 6.6 4.5 26.7 9.7 3.9 18.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF3343 PF11823.3 EIW68833.1 - 0.015 14.5 0.4 0.4 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Vps8 PF12816.2 EIW68833.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 DUF3074 PF11274.3 EIW68834.1 - 0.05 13.2 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) Pex24p PF06398.6 EIW68836.1 - 9.6e-28 96.9 6.8 3e-27 95.3 4.7 1.7 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin GST_N_3 PF13417.1 EIW68837.1 - 1.4e-09 38.0 0.0 2.3e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW68837.1 - 9.1e-08 32.1 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW68837.1 - 2.9e-06 27.1 0.0 5.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW68837.1 - 0.0071 16.7 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW68837.1 - 0.051 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_16 PF10294.4 EIW68839.1 - 2.9e-14 52.8 0.0 3.7e-12 46.0 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EIW68839.1 - 0.0024 18.4 0.0 0.005 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SAM_MT PF04445.8 EIW68839.1 - 0.053 12.6 0.0 0.25 10.4 0.0 1.9 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase Methyltransf_32 PF13679.1 EIW68839.1 - 0.094 12.4 0.2 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.9 EIW68839.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB RIX1 PF08167.7 EIW68840.1 - 2.5 7.7 10.4 0.056 13.1 0.4 3.0 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Arginosuc_synth PF00764.14 EIW68841.1 - 1.6e-154 514.6 0.0 1.8e-154 514.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EIW68841.1 - 0.0025 17.1 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EIW68841.1 - 0.0082 14.7 0.1 0.026 13.1 0.0 1.7 1 1 1 2 2 2 1 tRNA methyl transferase Cid2 PF09774.4 EIW68842.1 - 1.9e-27 96.2 0.0 1.1e-16 61.2 0.0 2.0 1 1 1 2 2 2 2 Caffeine-induced death protein 2 WD40 PF00400.27 EIW68846.1 - 3.3e-07 29.9 4.3 0.42 10.5 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat CDC45 PF02724.9 EIW68846.1 - 1.3 6.9 8.3 1.7 6.6 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Glycos_transf_1 PF00534.15 EIW68847.1 - 5.1e-22 78.0 0.2 1.7e-12 47.0 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIW68847.1 - 0.002 18.3 0.0 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EIW68847.1 - 0.037 14.2 0.0 0.1 12.9 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EIW68848.1 - 2.1e-06 27.6 0.0 6.3e-05 22.7 0.0 2.8 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EIW68848.1 - 5.2e-06 26.7 0.0 7.8e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain RNB PF00773.14 EIW68849.1 - 3.6e-90 302.5 0.0 5e-90 302.0 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EIW68849.1 - 9.8e-10 38.6 0.1 2.3e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 PIN domain Tubulin_3 PF14881.1 EIW68851.1 - 0.037 13.4 0.0 0.095 12.1 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain TPP_enzyme_N PF02776.13 EIW68851.1 - 0.038 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain zf-CCHC PF00098.18 EIW68853.1 - 0.00097 18.9 1.8 0.0015 18.3 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW68853.1 - 0.011 15.9 4.4 0.019 15.1 3.1 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain zf-CCHC_2 PF13696.1 EIW68853.1 - 0.011 15.2 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIW68853.1 - 6.7 6.2 7.8 0.81 9.2 1.7 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Atrophin-1 PF03154.10 EIW68853.1 - 9.6 4.1 9.6 7.5 4.5 3.2 2.0 2 0 0 2 2 2 0 Atrophin-1 family SR-25 PF10500.4 EIW68855.1 - 0.79 9.1 28.1 0.1 12.0 9.4 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein vATP-synt_E PF01991.13 EIW68859.1 - 5e-55 185.8 6.5 6.2e-55 185.5 4.5 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Vps35 PF03635.12 EIW68859.1 - 0.004 15.3 4.1 0.0054 14.9 2.9 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF4562 PF15123.1 EIW68859.1 - 0.11 12.3 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4562) Exo_endo_phos PF03372.18 EIW68860.1 - 7.5e-24 85.0 0.4 1.7e-23 83.8 0.2 1.6 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF606 PF04657.8 EIW68860.1 - 0.066 13.3 2.8 0.12 12.4 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF606 Rick_17kDa_Anti PF05433.10 EIW68860.1 - 0.11 12.1 0.2 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 Glycine zipper 2TM domain Pox_MCEL PF03291.11 EIW68861.1 - 2.3e-82 276.5 0.0 3.1e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 EIW68861.1 - 1.7e-09 38.0 0.0 3.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW68861.1 - 1.9e-09 38.0 0.0 3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW68861.1 - 2e-09 37.2 0.0 3.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW68861.1 - 2.6e-08 33.7 0.0 4.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW68861.1 - 4.9e-08 33.3 0.0 9.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW68861.1 - 9.5e-07 29.1 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain LAGLIDADG_2 PF03161.8 EIW68861.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family NodS PF05401.6 EIW68861.1 - 0.031 13.6 0.0 0.16 11.3 0.0 1.8 1 1 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.9 EIW68861.1 - 0.075 12.4 0.0 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 EIW68861.1 - 0.085 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family WD40 PF00400.27 EIW68862.1 - 1.5e-50 167.3 19.2 6.6e-11 41.6 0.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIW68862.1 - 3.9e-11 43.0 0.0 1.5e-05 24.8 0.0 3.3 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Trm112p PF03966.11 EIW68863.1 - 3.7e-18 65.6 0.1 4.9e-18 65.2 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein TF_Zn_Ribbon PF08271.7 EIW68863.1 - 0.13 11.5 0.4 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 TFIIB zinc-binding Ribosomal_S10 PF00338.17 EIW68864.1 - 2.6e-31 107.3 0.2 3e-31 107.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Amino_oxidase PF01593.19 EIW68865.1 - 2e-57 195.2 0.0 2.7e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIW68865.1 - 2.8e-14 52.8 0.6 6.3e-14 51.7 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW68865.1 - 4.7e-13 48.7 0.7 1.2e-05 24.4 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW68865.1 - 1.1e-05 25.4 1.1 0.0063 16.4 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW68865.1 - 1.6e-05 25.2 3.0 0.032 14.6 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW68865.1 - 2.2e-05 23.1 0.3 0.0037 15.7 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.14 EIW68865.1 - 7.6e-05 21.9 0.1 0.15 11.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EIW68865.1 - 0.00035 19.7 0.1 0.00061 18.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EIW68865.1 - 0.0015 18.5 1.0 0.15 12.1 0.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW68865.1 - 0.012 14.4 0.9 0.03 13.1 0.6 1.6 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EIW68865.1 - 0.019 13.9 0.4 0.11 11.4 0.2 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EIW68865.1 - 0.031 13.3 1.5 0.21 10.6 0.7 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 EIW68865.1 - 0.083 11.7 0.1 0.083 11.7 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A GLF PF03275.8 EIW68865.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 UDP-galactopyranose mutase SWIRM PF04433.12 EIW68866.1 - 8.8e-15 54.6 0.0 3.1e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 EIW68866.1 - 9.2e-10 37.9 4.5 1.6e-09 37.1 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EIW68866.1 - 2.1e-08 34.1 0.5 6.1e-08 32.6 0.2 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW68866.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Motilin_ghrelin PF04644.7 EIW68866.1 - 1.9 8.3 5.8 2.1 8.2 0.2 2.9 2 0 0 2 2 2 0 Motilin/ghrelin Transketolase_N PF00456.16 EIW68867.1 - 3.2e-119 397.6 0.0 4e-119 397.3 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EIW68867.1 - 4.1e-11 42.6 0.1 1.3e-06 28.0 0.1 3.3 1 1 1 2 2 2 2 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EIW68867.1 - 5.4e-06 25.5 0.0 0.0022 16.9 0.0 2.9 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EIW68867.1 - 8.3e-05 22.1 0.3 0.00021 20.9 0.2 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EIW68867.1 - 0.00017 20.4 0.4 0.00028 19.7 0.3 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 EIW68867.1 - 0.0015 18.4 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Complex1_LYR PF05347.10 EIW68868.1 - 5.7e-06 26.0 2.7 7.2e-06 25.7 0.9 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIW68868.1 - 0.00033 20.8 0.8 0.00098 19.2 0.4 2.0 2 1 0 2 2 2 1 Complex1_LYR-like DUF1227 PF06777.6 EIW68869.1 - 2.3e-54 183.0 0.7 4.1e-54 182.2 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EIW68869.1 - 1.9e-49 167.4 0.0 3.8e-49 166.4 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EIW68869.1 - 3.4e-44 150.7 0.0 6.3e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 EIW68869.1 - 0.0012 18.3 0.1 0.88 9.0 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EIW68869.1 - 0.01 15.6 0.0 0.42 10.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EIW68869.1 - 0.017 13.9 0.1 1.2 7.8 0.0 2.3 2 0 0 2 2 2 0 SNF2 family N-terminal domain YtxC PF08812.6 EIW68869.1 - 0.021 14.3 0.2 0.092 12.2 0.1 2.1 2 0 0 2 2 2 0 YtxC-like family GAS2 PF02187.12 EIW68870.1 - 0.0099 15.6 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain NPV_P10 PF05531.7 EIW68871.1 - 0.00058 20.0 3.4 0.0035 17.5 0.4 3.1 1 1 2 3 3 3 1 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.6 EIW68871.1 - 0.0071 15.6 1.7 0.96 8.6 0.2 2.3 1 1 1 2 2 2 2 Allexivirus 40kDa protein HAUS2 PF15003.1 EIW68871.1 - 0.015 14.3 0.4 0.25 10.3 0.0 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 Ax_dynein_light PF10211.4 EIW68871.1 - 0.028 14.2 0.2 0.049 13.4 0.1 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain IncA PF04156.9 EIW68871.1 - 0.028 13.9 1.5 0.052 13.1 1.0 1.5 1 0 0 1 1 1 0 IncA protein WXG100 PF06013.7 EIW68871.1 - 0.03 14.3 3.6 10 6.1 0.1 3.9 2 1 2 4 4 4 0 Proteins of 100 residues with WXG F_actin_bind PF08919.5 EIW68871.1 - 0.043 13.5 1.8 0.25 11.0 0.1 2.9 2 1 1 4 4 4 0 F-actin binding Ku_PK_bind PF08785.6 EIW68871.1 - 0.045 13.6 0.2 0.45 10.4 0.0 2.4 2 1 0 2 2 2 0 Ku C terminal domain like DUF1664 PF07889.7 EIW68871.1 - 0.049 13.4 2.4 0.71 9.6 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HsbA PF12296.3 EIW68871.1 - 0.052 13.4 0.6 0.49 10.2 0.1 2.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A FH2 PF02181.18 EIW68871.1 - 0.058 12.2 0.1 0.12 11.2 0.1 1.5 1 1 0 1 1 1 0 Formin Homology 2 Domain DUF964 PF06133.6 EIW68871.1 - 0.065 13.2 1.0 0.22 11.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF964) FUSC PF04632.7 EIW68871.1 - 0.072 11.5 1.5 0.079 11.3 1.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-Q PF13094.1 EIW68871.1 - 0.095 12.7 4.4 0.14 12.1 0.3 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Med4 PF10018.4 EIW68871.1 - 0.31 10.3 2.4 1.5 8.2 0.4 2.7 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DivIVA PF05103.8 EIW68871.1 - 0.64 10.0 2.7 3.3 7.7 0.4 2.9 1 1 0 2 2 2 0 DivIVA protein cNMP_binding PF00027.24 EIW68872.1 - 5e-41 138.4 0.1 3.1e-22 78.2 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EIW68872.1 - 5.2e-09 35.3 0.0 1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Arf PF00025.16 EIW68873.1 - 1.7e-38 131.5 0.0 9.7e-37 125.8 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.15 EIW68873.1 - 3.1e-13 49.2 0.1 1.5e-09 37.0 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EIW68873.1 - 3.4e-10 40.4 0.0 4.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EIW68873.1 - 2.7e-07 29.9 0.0 4.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EIW68873.1 - 2.8e-07 30.0 0.0 5.9e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EIW68873.1 - 6.1e-05 22.9 0.0 9.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EIW68873.1 - 0.0003 19.9 0.0 0.00038 19.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW68873.1 - 0.007 15.8 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EIW68873.1 - 0.015 14.5 0.1 0.036 13.3 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 EIW68873.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIW68873.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PALP PF00291.20 EIW68874.1 - 5.8e-55 186.6 0.0 5.6e-54 183.4 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aldolase_II PF00596.16 EIW68875.1 - 1.1e-39 135.9 0.0 1.5e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SSP160 PF06933.6 EIW68876.1 - 2 6.3 12.8 0.048 11.6 3.9 1.7 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 LSM PF01423.17 EIW68877.1 - 1.9e-15 56.1 0.0 2.6e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain EF-hand_1 PF00036.27 EIW68877.1 - 0.0016 17.6 0.2 0.0024 17.0 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EIW68877.1 - 0.016 15.3 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.1 EIW68877.1 - 0.096 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 EIW68877.1 - 0.1 11.9 0.3 0.18 11.1 0.2 1.3 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EIW68877.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.20 EIW68878.1 - 4.4e-35 121.0 0.0 5.5e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW68878.1 - 6e-13 48.4 0.0 8.1e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW68878.1 - 0.0018 18.0 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family CK1gamma_C PF12605.3 EIW68878.1 - 0.0033 17.9 1.7 0.0033 17.9 1.2 2.0 2 1 0 2 2 2 1 Casein kinase 1 gamma C terminal CPSF73-100_C PF11718.3 EIW68879.1 - 4.5e-59 199.4 0.0 7.5e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EIW68879.1 - 9.7e-28 96.6 0.0 1.9e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EIW68879.1 - 7.2e-17 61.6 0.9 7.2e-17 61.6 0.6 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW68879.1 - 2.5e-11 43.5 0.4 2.5e-11 43.5 0.3 2.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EIW68879.1 - 3.9e-09 36.1 0.1 8.1e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EIW68879.1 - 6.1e-07 29.2 1.0 4.4e-06 26.4 0.1 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain PRP3 PF08572.5 EIW68880.1 - 4.2e-65 219.2 9.2 8e-65 218.3 6.4 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EIW68880.1 - 8.3e-36 122.4 0.0 1.9e-35 121.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) GTP_cyclohydro2 PF00925.15 EIW68881.1 - 4.1e-63 211.6 0.0 3.5e-57 192.3 0.0 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF1772 PF08592.6 EIW68882.1 - 0.048 13.3 4.2 0.091 12.4 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Dynamin_M PF01031.15 EIW68883.1 - 4.4e-104 347.3 0.0 9.1e-104 346.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EIW68883.1 - 9.6e-55 184.9 0.0 1.6e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EIW68883.1 - 2.9e-26 91.2 1.3 6.2e-26 90.1 0.9 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIW68883.1 - 0.004 17.1 0.2 0.034 14.0 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW68883.1 - 0.061 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF1510 PF07423.6 EIW68884.1 - 0.014 14.7 0.8 0.014 14.7 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1510) DUF3595 PF12166.3 EIW68884.1 - 4 6.1 6.5 0.2 10.4 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3595) Selenoprotein_S PF06936.6 EIW68884.1 - 4.8 6.6 11.3 0.87 9.0 0.6 2.4 2 0 0 2 2 2 0 Selenoprotein S (SelS) SNF2_N PF00176.18 EIW68885.1 - 6.3e-48 163.0 0.0 6e-44 150.0 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW68885.1 - 1.1e-16 60.4 0.0 5.6e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW68885.1 - 7.4e-05 22.6 0.1 0.00028 20.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sybindin PF04099.7 EIW68886.1 - 2.5e-21 75.8 0.0 3.4e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family DNA_ligase_A_M PF01068.16 EIW68887.1 - 4.8e-34 117.4 0.7 2.1e-24 86.0 0.1 4.5 4 1 0 4 4 4 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIW68887.1 - 4.9e-34 117.6 0.0 8e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EIW68887.1 - 1.5e-16 60.5 0.0 6.1e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region WD40 PF00400.27 EIW68888.1 - 4.4e-11 42.2 6.3 0.00079 19.2 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat MMS1_N PF10433.4 EIW68888.1 - 0.14 10.2 0.0 0.22 9.6 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term CopD PF05425.8 EIW68889.1 - 0.21 11.7 10.0 1.5 9.0 0.4 2.5 2 0 0 2 2 2 0 Copper resistance protein D CM2 PF03021.9 EIW68889.1 - 0.28 10.7 1.8 0.3 10.6 0.1 1.8 2 0 0 2 2 2 0 Influenza C virus M2 protein DUF3112 PF11309.3 EIW68889.1 - 0.44 10.3 9.0 0.12 12.1 3.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) Abhydrolase_9_N PF15420.1 EIW68889.1 - 1.6 8.4 5.5 0.49 10.1 0.4 2.4 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus PrgI PF12666.2 EIW68889.1 - 2.6 8.2 9.8 0.33 11.1 1.0 2.7 2 1 0 2 2 2 0 PrgI family protein DUF1206 PF06724.6 EIW68889.1 - 2.9 7.7 10.5 0.58 9.9 1.9 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) PMP1_2 PF08114.6 EIW68889.1 - 2.9 7.4 7.1 0.55 9.7 0.8 2.5 1 1 1 2 2 2 0 ATPase proteolipid family DUF202 PF02656.10 EIW68889.1 - 7.5 6.8 9.4 3.7 7.8 3.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Acetyltransf_13 PF13880.1 EIW68890.1 - 3.9e-12 45.7 0.0 8.5e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EIW68890.1 - 1.5e-05 24.4 1.2 3.5e-05 23.2 0.8 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Dynamin_M PF01031.15 EIW68891.1 - 9.2e-110 366.0 0.0 1.4e-109 365.4 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EIW68891.1 - 7e-52 175.6 0.0 1.3e-51 174.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EIW68891.1 - 1.6e-27 95.2 0.8 3e-27 94.3 0.3 1.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIW68891.1 - 0.0055 16.6 0.0 0.99 9.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIW68891.1 - 0.026 15.0 0.0 0.078 13.4 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AIG1 PF04548.11 EIW68891.1 - 0.16 11.0 0.0 2.8 7.0 0.0 2.4 2 0 0 2 2 2 0 AIG1 family Lipase_GDSL_2 PF13472.1 EIW68892.1 - 2.1e-05 24.7 0.0 3.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family IFRD PF05004.8 EIW68893.1 - 0.00041 19.5 0.4 0.00048 19.2 0.3 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Apc5 PF12862.2 EIW68894.1 - 3.4e-13 49.2 0.6 8.1e-13 48.0 0.3 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_16 PF13432.1 EIW68894.1 - 0.0036 17.9 0.2 0.11 13.1 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW68894.1 - 0.044 13.7 0.6 1.4 8.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PGAP1 PF07819.8 EIW68895.1 - 7.2e-06 25.7 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EIW68895.1 - 2e-05 24.6 0.0 4.6e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EIW68895.1 - 2.4e-05 23.7 0.0 4.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EIW68895.1 - 5.2e-05 23.0 0.0 0.00012 21.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW68895.1 - 0.00016 21.3 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EIW68895.1 - 0.00018 20.7 0.0 0.00054 19.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 EIW68895.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Whi5 PF08528.6 EIW68896.1 - 5.9e-07 28.9 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Whi5 like SOG2 PF10428.4 EIW68896.1 - 9.3 4.7 27.7 9.9 4.6 18.6 1.5 1 1 0 1 1 1 0 RAM signalling pathway protein XPG_I PF00867.13 EIW68897.1 - 1.1e-14 54.2 0.0 1.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EIW68897.1 - 1.6e-05 25.1 0.0 3.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EIW68897.1 - 5.1e-05 23.4 0.0 0.00015 21.9 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_5 PF12688.2 EIW68897.1 - 0.03 14.3 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 Tetratrico peptide repeat EamA PF00892.15 EIW68898.1 - 1.5e-06 28.3 23.5 2.7e-05 24.2 2.8 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EIW68898.1 - 5.9e-06 25.3 9.9 5.2e-05 22.2 6.6 2.4 2 1 1 3 3 3 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EIW68898.1 - 0.00033 20.8 2.4 0.00033 20.8 1.7 2.6 2 0 0 2 2 2 1 Multidrug resistance efflux transporter UAA PF08449.6 EIW68898.1 - 0.002 17.0 5.4 0.0033 16.4 3.7 1.2 1 0 0 1 1 1 1 UAA transporter family bZIP_1 PF00170.16 EIW68899.1 - 2.9e-07 30.3 15.4 5.7e-07 29.3 10.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIW68899.1 - 3.1e-05 23.6 15.3 0.0002 21.1 10.6 2.1 1 1 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.10 EIW68899.1 - 0.37 10.3 3.6 0.64 9.5 2.5 1.4 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 EIW68899.1 - 0.63 9.6 6.0 0.89 9.1 4.1 1.2 1 0 0 1 1 1 0 IncA protein DUF4446 PF14584.1 EIW68899.1 - 1.3 8.8 4.0 1.9 8.2 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) bZIP_Maf PF03131.12 EIW68899.1 - 1.4 9.2 17.2 0.041 14.1 7.6 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor TMF_DNA_bd PF12329.3 EIW68899.1 - 1.5 8.6 8.6 3 7.6 6.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PRKCSH-like PF12999.2 EIW68899.1 - 2.8 7.4 4.6 4.2 6.9 3.2 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Atg14 PF10186.4 EIW68899.1 - 4.5 6.1 13.0 0.17 10.7 4.9 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Resolvase PF00239.16 EIW68902.1 - 0.0011 18.8 1.4 0.0019 18.1 1.0 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC_2 PF13696.1 EIW68902.1 - 0.0037 16.7 0.2 0.0077 15.7 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EIW68902.1 - 0.015 15.1 4.6 0.023 14.5 3.2 1.3 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.14 EIW68903.1 - 1.1e-42 145.6 0.0 1.7e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW68903.1 - 0.0018 18.0 0.3 0.0052 16.5 0.2 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain RCC1 PF00415.13 EIW68906.1 - 7.1e-15 54.9 12.1 0.00026 21.1 0.5 7.2 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIW68906.1 - 0.0032 17.0 0.0 0.0032 17.0 0.0 6.0 6 1 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat 2Fe-2S_thioredx PF01257.14 EIW68907.1 - 1.8e-56 189.8 0.0 2.1e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin GATase_2 PF00310.16 EIW68909.1 - 3e-24 85.3 0.0 1.2e-18 67.0 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIW68909.1 - 3.4e-15 56.1 0.0 8e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EIW68909.1 - 2.4e-12 46.6 0.1 4.2e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 EIW68909.1 - 1.2e-11 44.4 0.0 2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EIW68909.1 - 4.4e-07 28.8 0.0 1.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferases class-II UPRTase PF14681.1 EIW68909.1 - 0.14 11.3 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Vps54 PF07928.7 EIW68910.1 - 1.2e-53 180.8 1.8 2.4e-53 179.9 1.3 1.5 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EIW68910.1 - 2.4e-06 26.6 0.0 7.6e-06 25.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EIW68910.1 - 0.0045 16.7 1.5 0.0061 16.3 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Phage_tail_X PF05489.7 EIW68911.1 - 0.16 11.5 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X MIP-T3 PF10243.4 EIW68915.1 - 0.0027 16.2 4.3 0.0036 15.8 3.0 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 EIW68915.1 - 0.02 12.8 9.6 0.03 12.2 6.7 1.3 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EIW68915.1 - 0.039 13.1 11.5 0.064 12.5 8.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PPP4R2 PF09184.6 EIW68915.1 - 0.067 12.7 9.6 0.12 11.8 6.7 1.3 1 0 0 1 1 1 0 PPP4R2 DUF2457 PF10446.4 EIW68915.1 - 0.2 10.3 19.7 0.4 9.3 13.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Myc_N PF01056.13 EIW68915.1 - 0.27 10.3 8.4 0.05 12.7 3.5 1.5 2 0 0 2 2 2 0 Myc amino-terminal region Sigma70_ner PF04546.8 EIW68915.1 - 1.3 8.6 11.0 2.2 7.8 7.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF506 PF04720.7 EIW68915.1 - 1.5 8.4 3.9 3.3 7.2 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF506) NOA36 PF06524.7 EIW68915.1 - 1.7 7.7 14.0 2.9 7.0 9.7 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 EIW68915.1 - 3.4 5.5 13.6 5 5.0 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.4 EIW68915.1 - 6 5.5 11.0 9.1 4.9 7.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nucleoplasmin PF03066.10 EIW68915.1 - 6 6.3 18.8 12 5.3 13.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin CRA PF06589.6 EIW68916.1 - 0.083 12.2 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Otopetrin PF03189.8 EIW68916.1 - 0.12 11.2 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Otopetrin Ribosomal_S7e PF01251.13 EIW68917.1 - 1.3e-80 269.3 2.0 1.5e-80 269.1 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SBDS_C PF09377.5 EIW68918.1 - 4.2e-39 133.0 0.3 7.7e-39 132.2 0.2 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EIW68918.1 - 2.9e-30 103.9 0.9 5.5e-30 103.0 0.6 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein PRELI PF04707.9 EIW68920.1 - 3.1e-32 111.2 0.0 4.7e-23 81.4 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family MFS_1 PF07690.11 EIW68921.1 - 2.5e-33 115.2 80.4 1e-28 100.0 39.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Frag1 PF10277.4 EIW68922.1 - 3e-29 102.0 6.5 3e-29 102.0 4.5 2.0 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 EIW68922.1 - 0.0036 17.2 0.0 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF35 PF01796.12 EIW68922.1 - 0.032 14.4 0.6 0.1 12.8 0.3 2.0 2 0 0 2 2 2 0 DUF35 OB-fold domain Gly_transf_sug PF04488.10 EIW68923.1 - 5.7e-07 29.8 0.0 1.4e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Aldo_ket_red PF00248.16 EIW68924.1 - 1.4e-66 224.2 0.2 1.7e-66 223.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 EIW68925.1 - 1.8e-20 73.4 0.4 4.6e-20 72.2 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW68925.1 - 1.6e-09 37.8 0.1 5e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW68925.1 - 6.5e-07 29.1 0.9 7.6e-06 25.7 0.6 2.1 1 1 0 1 1 1 1 KR domain Aldo_ket_red PF00248.16 EIW68926.1 - 7.4e-48 162.7 0.0 8.7e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 EIW68927.1 - 2.5e-15 56.7 0.0 4.6e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW68927.1 - 3.4e-06 27.0 0.0 7.4e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW68927.1 - 4.3e-06 26.5 0.0 6.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 KR domain CUE PF02845.11 EIW68928.1 - 1.1e-05 24.7 0.0 2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 EIW68928.1 - 0.027 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif FdhE PF04216.7 EIW68929.1 - 0.025 14.2 0.1 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-C3HC4_3 PF13920.1 EIW68929.1 - 0.2 11.3 0.8 0.39 10.4 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PhyH PF05721.8 EIW68930.1 - 9.8e-06 25.7 0.1 2.3e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EIW68930.1 - 4e-05 22.2 0.1 0.04 12.4 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 EIW68930.1 - 0.0018 18.5 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 EIW68930.1 - 0.0035 17.8 0.0 0.0081 16.6 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EIW68930.1 - 0.076 11.8 0.1 0.15 10.9 0.0 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF35 PF01796.12 EIW68930.1 - 0.091 12.9 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 DUF35 OB-fold domain Epimerase PF01370.16 EIW68931.1 - 1.7e-09 37.5 0.0 2.8e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW68931.1 - 2.6e-06 26.3 0.0 8.8e-06 24.6 0.0 1.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW68931.1 - 1.9e-05 24.7 0.0 0.00012 22.1 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Asp_Glu_race PF01177.17 EIW68931.1 - 0.076 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase NAD_binding_4 PF07993.7 EIW68931.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.20 EIW68932.1 - 5e-18 65.5 0.2 3e-16 59.8 0.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW68932.1 - 6.2e-13 49.0 0.0 2.8e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW68932.1 - 6.8e-07 29.1 0.2 9e-06 25.4 0.1 2.1 2 0 0 2 2 2 1 KR domain Pyr_redox PF00070.22 EIW68932.1 - 0.018 15.4 0.4 0.042 14.2 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.10 EIW68932.1 - 0.055 12.3 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EIW68932.1 - 0.099 12.2 0.2 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.19 EIW68933.1 - 6.2e-60 203.0 17.2 7.4e-60 202.7 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW68933.1 - 1.8e-16 59.7 25.6 2.3e-16 59.4 17.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW68934.1 - 1.8e-12 46.5 8.6 2.1e-12 46.3 5.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter 7tm_1 PF00001.16 EIW68934.1 - 0.67 9.0 4.6 3.1 6.8 3.2 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2207 PF09972.4 EIW68934.1 - 2.5 6.5 5.5 2.6 6.5 3.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Sugar_tr PF00083.19 EIW68935.1 - 1.3e-34 119.5 5.7 1.8e-34 119.1 3.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW68935.1 - 3.4e-17 62.1 6.3 4.2e-17 61.8 4.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF805 PF05656.9 EIW68935.1 - 1.8 8.4 6.4 1.1 9.1 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF805) DUF2306 PF10067.4 EIW68935.1 - 2.3 8.3 9.2 40 4.3 0.0 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) PTCB-BRCT PF12738.2 EIW68936.1 - 0.00042 20.1 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EIW68936.1 - 0.0014 18.7 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EIW68936.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain Sigma70_r3 PF04539.11 EIW68936.1 - 0.27 11.1 3.9 4.8 7.1 0.1 3.2 3 0 0 3 3 3 0 Sigma-70 region 3 SAPS PF04499.10 EIW68937.1 - 1.8 7.1 14.1 3.9 6.0 9.8 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 EIW68937.1 - 4.4 5.2 25.1 7 4.5 17.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_23 PF13489.1 EIW68938.1 - 2.5e-09 37.0 0.0 3.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW68938.1 - 1e-06 29.1 0.0 2.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW68938.1 - 1.2e-06 28.1 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW68938.1 - 8e-06 26.2 0.0 1.7e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW68938.1 - 4.3e-05 23.8 0.0 7.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW68938.1 - 0.0022 17.1 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIW68938.1 - 0.0039 17.7 0.0 0.0078 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_L19e PF01280.15 EIW68939.1 - 8.2e-60 200.8 10.7 8.2e-60 200.8 7.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e KSHV_K8 PF07188.6 EIW68939.1 - 4.6 6.4 6.3 6.9 5.8 0.4 2.5 1 1 2 3 3 3 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein Guanylate_kin PF00625.16 EIW68942.1 - 8.2e-54 181.8 0.0 1e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_22 PF13401.1 EIW68942.1 - 5.3e-05 23.3 0.0 0.00052 20.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW68942.1 - 0.00012 22.0 0.1 0.00062 19.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW68942.1 - 0.00014 21.9 0.0 0.00045 20.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EIW68942.1 - 0.00037 19.9 0.0 0.00096 18.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EIW68942.1 - 0.00053 20.2 0.0 0.00098 19.4 0.0 1.6 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EIW68942.1 - 0.0009 18.4 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EIW68942.1 - 0.002 18.9 0.1 0.0042 17.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW68942.1 - 0.0022 18.3 0.1 0.17 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EIW68942.1 - 0.0028 18.0 0.0 0.0035 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EIW68942.1 - 0.0029 17.6 0.0 0.0036 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EIW68942.1 - 0.0079 16.1 0.8 0.024 14.6 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW68942.1 - 0.0099 15.6 0.1 0.036 13.8 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EIW68942.1 - 0.01 15.2 0.1 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EIW68942.1 - 0.025 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EIW68942.1 - 0.032 14.7 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein IstB_IS21 PF01695.12 EIW68942.1 - 0.044 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Septin PF00735.13 EIW68942.1 - 0.066 12.2 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.17 EIW68942.1 - 0.071 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase T2SE PF00437.15 EIW68942.1 - 0.077 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 EIW68942.1 - 0.079 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EIW68942.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EIW68942.1 - 0.1 12.4 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EIW68942.1 - 0.12 10.9 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EIW68942.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 EIW68942.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EIW68942.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EIW68943.1 - 1.4e-80 270.3 0.0 2.2e-80 269.6 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EIW68943.1 - 3.1e-06 26.7 0.0 6.7e-05 22.4 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EIW68943.1 - 6.3e-05 21.8 1.8 0.003 16.3 0.0 3.1 3 0 0 3 3 3 1 G-protein alpha subunit AAA_22 PF13401.1 EIW68943.1 - 7.7e-05 22.8 0.0 0.00023 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EIW68943.1 - 0.00019 20.9 0.0 0.0036 16.7 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EIW68943.1 - 0.0002 21.3 0.0 0.00074 19.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.13 EIW68943.1 - 0.00034 19.9 0.0 0.023 13.9 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_33 PF13671.1 EIW68943.1 - 0.00052 19.9 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EIW68943.1 - 0.00055 19.8 0.0 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EIW68943.1 - 0.00078 18.5 0.0 0.0018 17.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.2 EIW68943.1 - 0.0015 18.0 0.2 0.0024 17.3 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 EIW68943.1 - 0.0024 18.6 1.9 0.0055 17.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EIW68943.1 - 0.003 16.4 0.0 0.0079 15.0 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain PduV-EutP PF10662.4 EIW68943.1 - 0.0032 16.9 0.1 0.022 14.2 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 EIW68943.1 - 0.0043 16.2 0.0 0.013 14.7 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family cobW PF02492.14 EIW68943.1 - 0.0044 16.4 0.0 0.45 9.9 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EIW68943.1 - 0.0048 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EIW68943.1 - 0.0064 15.9 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 EIW68943.1 - 0.0071 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 EIW68943.1 - 0.008 15.7 0.1 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EIW68943.1 - 0.011 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EIW68943.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase 6PF2K PF01591.13 EIW68943.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PRK PF00485.13 EIW68943.1 - 0.017 14.7 0.1 0.3 10.6 0.0 2.6 2 1 1 3 3 3 0 Phosphoribulokinase / Uridine kinase family SRPRB PF09439.5 EIW68943.1 - 0.022 13.9 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 EIW68943.1 - 0.038 14.2 0.3 0.12 12.7 0.0 2.1 3 0 0 3 3 1 0 AAA domain ArgK PF03308.11 EIW68943.1 - 0.045 12.5 0.0 1 8.0 0.0 2.1 2 0 0 2 2 2 0 ArgK protein KAP_NTPase PF07693.9 EIW68943.1 - 0.055 12.4 0.0 0.071 12.0 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain DUF258 PF03193.11 EIW68943.1 - 0.14 11.3 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Thymidylate_kin PF02223.12 EIW68943.1 - 0.32 10.3 0.0 0.32 10.3 0.0 2.0 3 0 0 3 3 2 0 Thymidylate kinase Ras PF00071.17 EIW68944.1 - 1.4e-52 177.3 0.0 1.6e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW68944.1 - 5.5e-16 59.1 0.0 7.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW68944.1 - 1.5e-07 30.8 0.0 1.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Peptidase_M22 PF00814.20 EIW68945.1 - 3.7e-75 252.8 0.0 4.7e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family zf-C4_Topoisom PF01396.14 EIW68947.1 - 0.089 12.3 0.5 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-RING_3 PF14369.1 EIW68947.1 - 0.1 12.6 1.8 9.1 6.3 0.1 2.4 2 0 0 2 2 2 0 zinc-finger DZR PF12773.2 EIW68947.1 - 0.11 12.3 1.8 0.39 10.5 1.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon DLH PF01738.13 EIW68948.1 - 1.6e-12 47.2 0.0 6.9e-12 45.1 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Sigma70_ner PF04546.8 EIW68948.1 - 0.0055 16.3 5.4 0.016 14.8 3.7 1.8 1 0 0 1 1 1 1 Sigma-70, non-essential region Vfa1 PF08432.5 EIW68948.1 - 0.0067 16.4 0.7 0.0067 16.4 0.5 2.1 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.6 EIW68948.1 - 0.45 8.5 4.2 0.71 7.9 2.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 EIW68948.1 - 1.4 6.7 14.4 2.1 6.1 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family LAT PF15234.1 EIW68948.1 - 1.8 7.9 8.7 3.6 7.0 6.0 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells RXT2_N PF08595.6 EIW68948.1 - 2.9 7.6 8.2 6.8 6.4 5.7 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.7 EIW68948.1 - 3 7.0 13.2 5.9 6.0 9.2 1.4 1 0 0 1 1 1 0 SDA1 HSP90 PF00183.13 EIW68948.1 - 5.1 5.3 9.8 8.5 4.6 6.8 1.3 1 0 0 1 1 1 0 Hsp90 protein CobT PF06213.7 EIW68948.1 - 5.6 6.0 14.1 11 5.1 9.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.1 EIW68948.1 - 6.2 6.4 6.3 18 4.9 4.4 1.7 1 0 0 1 1 1 0 FAM176 family CBM_21 PF03370.8 EIW68949.1 - 5.5e-25 87.5 0.1 1e-24 86.6 0.1 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit DUF2890 PF11081.3 EIW68949.1 - 0.064 13.3 2.7 0.51 10.3 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Arm PF00514.18 EIW68950.1 - 5.1e-92 298.9 13.8 6.1e-13 48.0 0.0 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIW68950.1 - 3.6e-24 84.8 0.7 1.1e-06 28.7 0.0 5.9 2 1 5 7 7 6 6 HEAT repeats HEAT_EZ PF13513.1 EIW68950.1 - 7e-23 80.4 2.0 4.7e-08 33.2 0.0 6.0 6 0 0 6 6 6 3 HEAT-like repeat IBB PF01749.15 EIW68950.1 - 2.4e-21 75.7 4.5 3.8e-21 75.0 3.1 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EIW68950.1 - 1.9e-19 67.9 1.3 8.4e-06 25.4 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 EIW68950.1 - 8.7e-09 34.8 0.0 0.0023 17.0 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EIW68950.1 - 1.7e-05 23.4 0.0 0.00053 18.4 0.0 2.6 1 1 2 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.1 EIW68950.1 - 2.4e-05 24.1 1.8 0.19 11.6 0.0 4.5 3 2 2 5 5 5 3 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 EIW68950.1 - 0.00055 20.1 0.1 0.48 11.0 0.0 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EIW68950.1 - 0.0013 17.0 0.1 0.053 11.7 0.0 2.4 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 EIW68950.1 - 0.0023 17.8 0.0 0.56 10.1 0.0 4.0 2 2 2 5 5 5 1 V-ATPase subunit H DUF3552 PF12072.3 EIW68950.1 - 0.21 10.7 4.5 0.3 10.2 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CwfJ_C_1 PF04677.10 EIW68951.1 - 1.6e-31 108.5 0.1 2.3e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EIW68951.1 - 5.4e-23 81.3 0.0 5.4e-23 81.3 0.0 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 DUF3680 PF12441.3 EIW68952.1 - 0.93 9.3 4.2 1.7 8.5 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) 3HCDH_N PF02737.13 EIW68953.1 - 1.4e-46 158.4 0.0 2.4e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EIW68953.1 - 4.8e-34 116.6 0.0 9.8e-34 115.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Mt_ATP-synt_B PF05405.9 EIW68954.1 - 6.1e-44 149.3 7.2 7.4e-44 149.0 5.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Leo1 PF04004.8 EIW68955.1 - 2.2e-35 121.8 0.3 5.4e-34 117.3 0.0 2.3 2 0 0 2 2 2 2 Leo1-like protein RRM_1 PF00076.17 EIW68956.1 - 2.9e-23 81.2 0.0 5.5e-12 45.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 EIW68956.1 - 6.8e-16 56.7 0.0 0.0075 15.6 0.0 5.6 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat RRM_6 PF14259.1 EIW68956.1 - 6.9e-14 51.5 0.0 6.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW68956.1 - 1.3e-12 47.3 0.0 4.1e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arrestin_C PF02752.17 EIW68957.1 - 3.3e-17 62.8 0.4 2.8e-16 59.8 0.0 2.7 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain DUF4499 PF14934.1 EIW68959.1 - 4e-07 29.8 0.2 6.4e-07 29.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.4 EIW68959.1 - 0.00019 21.6 0.0 0.00057 20.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2470) Pyridoxal_deC PF00282.14 EIW68960.1 - 9.8e-18 63.7 0.0 1.7e-17 62.9 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EIW68960.1 - 5.5e-07 28.6 0.0 1.7e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EIW68960.1 - 0.0013 17.8 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family H2TH PF06831.9 EIW68961.1 - 4.2e-22 77.7 0.0 6.5e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 EIW68961.1 - 1.1e-19 70.8 0.0 1.8e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.6 EIW68961.1 - 0.00015 20.4 0.0 0.00024 19.7 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Redoxin PF08534.5 EIW68962.1 - 1.3e-29 102.5 0.1 1.6e-29 102.3 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EIW68962.1 - 2.9e-15 56.0 0.0 3.8e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Elong_Iki1 PF10483.4 EIW68963.1 - 0.00013 21.4 0.2 0.00092 18.6 0.1 1.9 1 1 0 1 1 1 1 Elongator subunit Iki1 DUF2348 PF09807.4 EIW68963.1 - 0.014 14.5 0.0 0.031 13.3 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2348) HlyIII PF03006.15 EIW68964.1 - 1.1e-41 142.6 26.1 1.4e-41 142.3 18.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related WGG PF10273.4 EIW68965.1 - 1.4e-27 95.6 0.0 2.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Tricorn_PDZ PF14685.1 EIW68965.1 - 0.094 12.5 0.1 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain DDOST_48kD PF03345.9 EIW68966.1 - 4e-121 404.5 0.0 4.5e-121 404.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta AstA PF04958.7 EIW68966.1 - 0.087 11.2 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit zf-RanBP PF00641.13 EIW68967.1 - 1.7e-06 27.0 11.4 0.0031 16.5 2.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Rubredoxin PF00301.15 EIW68967.1 - 0.34 10.8 5.9 0.8 9.6 0.6 2.6 2 0 0 2 2 2 0 Rubredoxin DZR PF12773.2 EIW68967.1 - 1.4 8.7 7.4 5.7 6.8 5.3 2.0 1 1 1 2 2 2 0 Double zinc ribbon Npa1 PF11707.3 EIW68969.1 - 1.2e-51 175.6 0.0 1.7e-50 171.8 0.0 2.6 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal AA_kinase PF00696.23 EIW68970.1 - 3.7e-37 128.1 0.1 5.6e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EIW68970.1 - 4.3e-12 45.5 2.7 2.9e-05 23.7 0.0 3.3 4 0 0 4 4 4 2 PUA domain ADH_N PF08240.7 EIW68971.1 - 8.3e-22 77.0 0.3 2.1e-21 75.7 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW68971.1 - 1e-12 47.7 0.0 1.9e-07 30.7 0.0 2.6 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW68971.1 - 0.00013 22.8 0.0 0.00028 21.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIW68971.1 - 0.00077 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.7 EIW68971.1 - 0.0056 17.1 0.0 0.018 15.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW68971.1 - 0.0062 16.1 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW68971.1 - 0.055 14.0 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 EIW68971.1 - 0.058 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_26 PF13659.1 EIW68971.1 - 0.096 12.7 0.0 0.26 11.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EIW68971.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain V-ATPase_C PF03223.10 EIW68972.1 - 1.4e-110 369.7 0.0 1.5e-110 369.6 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Peptidase_M48 PF01435.13 EIW68973.1 - 2.5e-30 105.7 0.0 4.5e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 His_Phos_1 PF00300.17 EIW68974.1 - 4.8e-15 56.0 0.0 7.3e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ank_2 PF12796.2 EIW68975.1 - 1.4e-11 44.5 0.0 3.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIW68975.1 - 1.5e-11 43.5 0.5 3.1e-06 26.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIW68975.1 - 1.4e-10 41.0 0.1 3.3e-08 33.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.19 EIW68975.1 - 1.5e-07 31.2 0.9 4.2e-07 29.8 0.4 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.1 EIW68975.1 - 2.2e-07 31.2 0.1 1.1e-05 25.8 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW68975.1 - 0.00045 20.1 0.1 0.03 14.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Calreticulin PF00262.13 EIW68975.1 - 0.02 13.5 0.3 0.038 12.6 0.2 1.3 1 0 0 1 1 1 0 Calreticulin family Epimerase PF01370.16 EIW68976.1 - 5.3e-11 42.4 0.0 7.6e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW68976.1 - 8.8e-08 31.1 0.0 1.3e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW68976.1 - 1e-06 28.8 0.1 8.6e-06 25.8 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW68976.1 - 8.1e-06 24.9 0.0 2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Mito_carr PF00153.22 EIW68977.1 - 1.1e-71 236.6 3.5 1.8e-23 82.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein SR-25 PF10500.4 EIW68978.1 - 0.00024 20.6 7.6 0.00041 19.8 5.3 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Ashwin PF15323.1 EIW68978.1 - 0.1 12.5 3.0 0.15 12.0 2.1 1.2 1 0 0 1 1 1 0 Developmental protein MelC1 PF06236.6 EIW68978.1 - 0.25 11.3 4.1 0.58 10.1 2.9 1.5 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 CDK2AP PF09806.4 EIW68978.1 - 0.59 10.3 4.8 0.9 9.7 3.4 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein BUD22 PF09073.5 EIW68978.1 - 0.6 9.1 3.7 0.79 8.7 2.6 1.1 1 0 0 1 1 1 0 BUD22 Peptidase_S21 PF00716.12 EIW68978.1 - 1 8.6 6.3 1.5 8.0 4.4 1.2 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) PsbQ PF05757.6 EIW68978.1 - 1.8 7.9 3.7 2.8 7.3 2.6 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) zf-CCHC PF00098.18 EIW68979.1 - 0.00022 20.9 1.3 0.00036 20.3 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW68979.1 - 0.06 13.0 0.5 0.2 11.3 0.4 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIW68979.1 - 0.11 12.2 1.3 0.26 11.0 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW68979.1 - 0.31 11.2 7.0 0.086 13.0 2.7 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW68979.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Helitron_like_N PF14214.1 EIW68980.1 - 0.02 14.5 0.4 0.032 13.9 0.2 1.3 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus DUF4501 PF14946.1 EIW68981.1 - 0.066 12.6 0.2 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) zf-H2C2_2 PF13465.1 EIW68983.1 - 1.1 9.6 4.5 7.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Zn_Tnp_IS1 PF03811.8 EIW68983.1 - 9.4 5.8 7.0 18 4.9 0.2 2.4 2 0 0 2 2 2 0 InsA N-terminal domain Myosin_head PF00063.16 EIW68985.1 - 1.2e-233 777.1 0.0 1.2e-233 777.1 0.0 2.6 3 1 1 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EIW68985.1 - 4e-07 28.2 49.8 4e-07 28.2 34.5 4.2 1 1 3 4 4 4 2 Myosin tail Myosin_N PF02736.14 EIW68985.1 - 3.6e-05 23.3 0.0 9.3e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 EIW68985.1 - 0.13 12.3 4.0 0.14 12.2 0.0 3.2 2 1 0 2 2 2 0 AAA domain MULE PF10551.4 EIW68986.1 - 1.9e-13 50.3 1.4 9.7e-11 41.7 0.2 3.6 2 1 0 2 2 2 1 MULE transposase domain UCH PF00443.24 EIW68986.1 - 5.3e-09 35.5 0.0 1.4e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase rve PF00665.21 EIW68986.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain UCH_1 PF13423.1 EIW68986.1 - 0.17 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DEAD PF00270.24 EIW68987.1 - 3.2e-41 140.6 0.0 4.4e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW68987.1 - 4.3e-23 80.9 0.1 7.8e-23 80.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCCH PF00642.19 EIW68988.1 - 1.6e-06 27.6 8.8 4.9e-05 22.9 1.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIW68988.1 - 0.5 10.4 13.4 0.33 11.0 2.4 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHC PF00098.18 EIW68991.1 - 0.00022 20.9 1.3 0.00034 20.4 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW68991.1 - 0.055 13.1 0.5 0.19 11.4 0.4 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIW68991.1 - 0.12 12.1 1.3 0.24 11.1 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 EIW68991.1 - 1.8 8.4 7.5 6.3 6.7 5.2 2.0 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF2587 PF10759.4 EIW68992.1 - 0.082 12.2 0.1 0.2 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) gag-asp_proteas PF13975.1 EIW68993.1 - 1.5e-08 34.3 0.0 2.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIW68993.1 - 9.2e-06 26.0 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.3 EIW68993.1 - 0.00074 18.8 0.0 0.00092 18.5 0.0 1.1 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP PF00077.15 EIW68993.1 - 0.0041 17.0 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIW68993.1 - 0.15 11.5 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Pkinase PF00069.20 EIW68994.1 - 6.8e-70 235.1 0.0 8.6e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW68994.1 - 1.3e-31 109.6 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIW68994.1 - 2.3e-05 23.5 0.0 7.8e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW68994.1 - 0.00035 20.3 0.1 0.001 18.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW68994.1 - 0.0031 16.5 0.0 0.023 13.6 0.0 2.0 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIW68994.1 - 0.036 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family OPA3 PF07047.7 EIW68995.1 - 9.1e-33 112.8 0.0 1.4e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) PsbQ PF05757.6 EIW68995.1 - 0.006 16.0 0.3 0.011 15.1 0.2 1.4 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) CsbD PF05532.7 EIW68996.1 - 0.37 10.4 5.3 14 5.4 0.5 2.1 1 1 0 1 1 1 0 CsbD-like tRNA-synt_2d PF01409.15 EIW68997.1 - 2.4e-46 157.9 0.1 1.2e-25 90.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EIW68997.1 - 9.3e-21 73.8 0.0 2.8e-20 72.2 0.0 1.9 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain PRMT5 PF05185.11 EIW68998.1 - 3.6e-10 39.3 0.0 4.5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 EIW68998.1 - 3.7e-07 29.5 0.1 5.1e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EIW68998.1 - 3.9e-05 23.6 0.0 0.00012 22.0 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW68998.1 - 0.00053 20.5 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW68998.1 - 0.00073 18.9 0.1 0.0014 17.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EIW68998.1 - 0.0015 19.0 0.0 0.076 13.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW68998.1 - 0.0031 17.2 0.0 0.0051 16.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW68998.1 - 0.072 12.6 0.1 0.31 10.6 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EIW68998.1 - 0.075 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Lactamase_B PF00753.22 EIW68999.1 - 1.6e-09 37.6 0.2 2.5e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW68999.1 - 8e-06 25.5 0.3 1.1e-05 25.1 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Syja_N PF02383.13 EIW69000.1 - 2.5e-69 233.4 0.0 3.9e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EIW69000.1 - 6.8e-24 85.1 0.0 1.2e-23 84.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIW69000.1 - 0.024 14.2 0.1 0.14 11.7 0.0 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase RhoGAP PF00620.22 EIW69001.1 - 2.4e-31 108.4 0.0 3.8e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain TB2_DP1_HVA22 PF03134.14 EIW69002.1 - 8.4e-08 31.8 2.9 8.4e-08 31.8 2.0 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family RdRP PF05183.7 EIW69003.1 - 2.8e-90 303.6 0.0 3.8e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase NAD_binding_8 PF13450.1 EIW69004.1 - 1.5e-10 40.9 0.2 3.6e-10 39.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EIW69004.1 - 2e-10 40.3 0.0 1.8e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EIW69004.1 - 0.00068 19.7 0.4 0.0016 18.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW69004.1 - 0.015 14.2 0.1 0.021 13.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EIW69004.1 - 0.02 13.3 0.3 0.029 12.8 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 EIW69004.1 - 0.021 13.7 0.3 0.037 12.9 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW69004.1 - 0.032 14.0 0.3 0.067 13.0 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW69004.1 - 0.04 13.0 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIW69004.1 - 0.078 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 EIW69004.1 - 0.11 11.5 0.1 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EIW69004.1 - 0.15 11.1 0.2 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DUF3431 PF11913.3 EIW69005.1 - 1.1e-12 47.8 0.0 4.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) Exo_endo_phos PF03372.18 EIW69006.1 - 5.7e-11 42.8 0.2 1e-10 42.0 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIW69006.1 - 0.01 15.4 0.0 0.062 12.9 0.0 2.1 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Colicin_Ia PF11504.3 EIW69006.1 - 0.093 12.6 0.2 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Colicin Ia PRA1 PF03208.14 EIW69007.1 - 2.1e-38 131.0 0.8 2.3e-38 130.9 0.6 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF2721 PF11026.3 EIW69007.1 - 0.11 12.1 1.8 0.5 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) NADH5_C PF06455.6 EIW69007.1 - 0.23 10.8 5.0 0.31 10.3 3.4 1.2 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus UvrD-helicase PF00580.16 EIW69008.1 - 7.2e-65 219.3 0.0 2.1e-64 217.7 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EIW69008.1 - 3.4e-47 161.6 0.0 6.2e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EIW69008.1 - 3.3e-12 45.9 2.1 5.1e-12 45.3 0.2 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EIW69008.1 - 3.2e-06 26.8 0.1 0.00041 20.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EIW69008.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIW69008.1 - 0.032 14.2 0.3 0.29 11.0 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.13 EIW69008.1 - 0.075 12.5 0.1 7.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Arg_tRNA_synt_N PF03485.11 EIW69008.1 - 0.099 13.1 0.1 0.41 11.2 0.0 2.0 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain FSH1 PF03959.8 EIW69009.1 - 3.6e-53 180.1 0.0 4.1e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EIW69009.1 - 8.2e-05 22.3 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW69009.1 - 0.0014 18.5 0.1 0.04 13.7 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 EIW69009.1 - 0.0063 15.4 0.1 2.5 6.8 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2048) Spectrin PF00435.16 EIW69010.1 - 0.0075 16.5 2.8 0.0075 16.5 2.0 6.4 4 1 1 6 6 6 1 Spectrin repeat GAS PF13851.1 EIW69010.1 - 0.0079 15.4 73.8 0.021 13.9 4.8 5.9 1 1 3 5 5 5 4 Growth-arrest specific micro-tubule binding IncA PF04156.9 EIW69010.1 - 2.8 7.5 110.8 0.33 10.5 13.4 6.4 1 1 2 4 4 4 0 IncA protein Glyco_hydro_1 PF00232.13 EIW69011.1 - 0.0034 15.6 0.3 0.0048 15.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Aminotran_1_2 PF00155.16 EIW69012.1 - 1.1e-54 185.7 0.0 3.1e-43 148.1 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW69012.1 - 0.00022 20.4 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EIW69012.1 - 0.0007 18.2 0.0 0.0013 17.3 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 EIW69012.1 - 0.016 13.9 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Tmemb_18A PF09771.4 EIW69012.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 SYS1 PF09801.4 EIW69013.1 - 4.9e-30 104.4 2.5 3.3e-22 79.0 0.7 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DUF2454 PF10521.4 EIW69015.1 - 1.8e-27 96.1 0.1 2.6e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Vps51 PF08700.6 EIW69016.1 - 2.5e-14 52.8 0.2 1.7e-13 50.2 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Zw10 PF06248.8 EIW69016.1 - 0.0055 14.9 0.0 0.009 14.2 0.0 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 CGI-121 PF08617.5 EIW69017.1 - 4.6e-31 107.6 0.0 5.6e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bestrophin PF01062.16 EIW69018.1 - 5e-41 140.5 0.7 2.5e-23 82.4 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel GtrA PF04138.9 EIW69018.1 - 3.3 7.7 8.6 5.8 6.9 2.2 3.0 2 1 1 3 3 3 0 GtrA-like protein Bestrophin PF01062.16 EIW69019.1 - 7.6e-29 100.5 3.5 7.4e-20 71.0 0.2 2.0 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.16 EIW69020.1 - 1.3e-24 86.6 0.1 1.2e-23 83.4 0.1 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel BPD_transp_2 PF02653.11 EIW69020.1 - 0.046 12.6 0.2 0.046 12.6 0.1 1.6 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component MAP65_ASE1 PF03999.7 EIW69021.1 - 9.9e-61 206.1 1.6 9.9e-61 206.1 1.1 2.0 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) EF-hand_6 PF13405.1 EIW69022.1 - 4.2e-07 29.3 0.1 0.00095 18.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EIW69022.1 - 4.7e-06 26.6 1.0 8.3e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EIW69022.1 - 0.00017 21.1 0.1 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EIW69022.1 - 0.00067 18.7 0.1 0.09 12.1 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EIW69022.1 - 0.017 14.4 0.0 0.17 11.2 0.0 2.4 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.4 EIW69022.1 - 0.2 11.6 1.1 0.8 9.7 0.0 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region GMC_oxred_N PF00732.14 EIW69023.1 - 8e-50 169.6 0.0 1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW69023.1 - 3.3e-34 118.2 0.0 5.2e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EIW69023.1 - 0.00013 21.9 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW69023.1 - 0.00098 18.1 0.1 0.009 14.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW69023.1 - 0.0012 17.7 2.4 0.024 13.5 0.2 2.6 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 EIW69023.1 - 0.0014 17.5 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EIW69023.1 - 0.0034 17.2 0.1 0.017 14.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW69023.1 - 0.017 15.1 0.1 0.66 9.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SpoVAD PF07451.6 EIW69023.1 - 0.05 12.0 0.1 0.11 10.9 0.1 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) NAD_binding_9 PF13454.1 EIW69023.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pkinase PF00069.20 EIW69024.1 - 1.1e-72 244.3 0.0 1.2e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69024.1 - 1.3e-30 106.3 0.0 1.6e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW69024.1 - 0.00059 18.8 0.0 0.00082 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW69024.1 - 0.0029 17.3 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIW69024.1 - 0.029 13.2 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 tRNA_int_endo PF01974.12 EIW69025.1 - 2.5e-08 33.6 0.0 4.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain NUDE_C PF04880.8 EIW69025.1 - 0.06 13.6 0.2 0.088 13.1 0.1 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Med21 PF11221.3 EIW69025.1 - 1.2 9.1 6.1 0.97 9.3 3.0 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF4169 PF13770.1 EIW69025.1 - 2.3 8.2 11.2 4.5 7.2 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) LSM PF01423.17 EIW69026.1 - 9.7e-13 47.4 0.1 1.4e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain UbiA PF01040.13 EIW69027.1 - 1.6e-31 109.4 17.1 2.2e-31 109.0 11.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Peptidase_M50B PF13398.1 EIW69028.1 - 1e-49 168.6 20.1 1.3e-49 168.2 13.9 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DUF1228 PF06779.9 EIW69028.1 - 0.9 9.5 4.6 3.6 7.6 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) zf-DHHC PF01529.15 EIW69028.1 - 1 8.7 7.6 0.28 10.5 0.4 2.4 1 1 1 2 2 2 0 DHHC palmitoyltransferase Lyase_1 PF00206.15 EIW69029.1 - 1.8e-118 395.2 0.0 2.5e-118 394.8 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EIW69029.1 - 2.9e-20 72.0 0.0 7.2e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 EIW69029.1 - 0.035 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Nop25 PF09805.4 EIW69030.1 - 1.3 9.0 24.1 1.8 8.6 16.7 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) 2OG-FeII_Oxy_2 PF13532.1 EIW69031.1 - 1.5e-25 90.2 0.0 1.8e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW69031.1 - 0.015 15.5 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily KH_3 PF13014.1 EIW69032.1 - 0.23 11.1 1.9 0.76 9.4 1.3 1.9 1 0 0 1 1 1 0 KH domain START PF01852.14 EIW69033.1 - 6.4e-18 64.8 0.1 2.6e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 START domain Dopey_N PF04118.9 EIW69034.1 - 7.7e-104 346.7 0.4 5.2e-103 344.0 0.0 2.3 2 0 0 2 2 2 1 Dopey, N-terminal Peptidase_M64 PF09471.5 EIW69034.1 - 0.19 11.3 0.0 0.42 10.2 0.0 1.5 1 0 0 1 1 1 0 IgA Peptidase M64 Bunya_NS-S PF01104.12 EIW69034.1 - 0.58 9.6 10.6 0.27 10.7 1.9 3.6 3 0 0 3 3 3 0 Bunyavirus non-structural protein NS-s NIF3 PF01784.13 EIW69035.1 - 3.2e-59 200.4 0.0 3.9e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) PsbQ PF05757.6 EIW69037.1 - 1.7 8.0 4.9 3 7.2 3.1 1.5 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) SR-25 PF10500.4 EIW69037.1 - 7 6.0 13.9 1.2 8.6 1.0 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3716 PF12511.3 EIW69039.1 - 0.37 10.4 5.0 0.63 9.6 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) DUF3022 PF11226.3 EIW69041.1 - 0.12 12.2 0.1 22 4.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3022) zf-CCHC PF00098.18 EIW69042.1 - 0.0044 16.8 1.9 0.0075 16.1 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle PepSY_2 PF13670.1 EIW69042.1 - 0.76 9.7 2.6 0.63 9.9 0.7 1.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF2587 PF10759.4 EIW69044.1 - 0.0097 15.3 0.1 0.025 13.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2587) DUF605 PF04652.11 EIW69044.1 - 8.2 5.7 12.1 14 4.9 8.4 1.3 1 0 0 1 1 1 0 Vta1 like zf-CCHC PF00098.18 EIW69045.1 - 0.00063 19.5 1.5 0.0012 18.6 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle B56 PF01603.15 EIW69045.1 - 0.061 11.9 2.0 0.081 11.5 1.4 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) BRF1 PF07741.8 EIW69045.1 - 0.8 9.9 7.3 0.21 11.8 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain CLPTM1 PF05602.7 EIW69046.1 - 1.7e-130 435.6 0.0 2.3e-130 435.2 0.0 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EIW69046.1 - 0.00032 20.1 1.1 0.00064 19.2 0.2 2.0 2 0 0 2 2 2 1 PQ loop repeat 2TM PF13239.1 EIW69046.1 - 0.25 11.4 4.5 0.31 11.1 0.1 3.0 2 1 1 3 3 3 0 2TM domain Phosphodiest PF01663.17 EIW69047.1 - 9.5e-10 38.3 0.3 2.1e-09 37.2 0.1 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EIW69047.1 - 0.00015 21.2 0.1 0.00024 20.6 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily ABC_tran PF00005.22 EIW69048.1 - 5.9e-33 114.0 0.0 1.1e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EIW69048.1 - 1.4e-22 80.4 8.8 1.9e-22 79.9 6.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EIW69048.1 - 3.6e-07 29.6 0.2 6.6e-05 22.2 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW69048.1 - 1.3e-06 28.6 0.1 0.0026 17.7 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EIW69048.1 - 8.7e-05 22.5 0.3 0.00035 20.6 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW69048.1 - 0.00041 20.4 0.1 0.031 14.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EIW69048.1 - 0.0011 18.4 0.2 0.0026 17.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 EIW69048.1 - 0.0041 16.7 1.6 0.083 12.4 0.4 3.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIW69048.1 - 0.006 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EIW69048.1 - 0.0095 15.8 0.2 0.057 13.3 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EIW69048.1 - 0.014 14.8 0.1 0.2 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 EIW69048.1 - 0.016 15.0 1.0 0.66 9.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 Diacid_rec PF05651.8 EIW69048.1 - 0.016 14.5 1.5 0.95 8.8 0.0 2.5 1 1 1 2 2 2 0 Putative sugar diacid recognition AAA_17 PF13207.1 EIW69048.1 - 0.016 15.9 0.1 0.056 14.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EIW69048.1 - 0.024 14.0 0.2 2.6 7.4 0.0 2.7 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 EIW69048.1 - 0.08 13.2 0.2 0.52 10.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.18 EIW69048.1 - 0.083 12.8 0.1 0.22 11.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase NEMO PF11577.3 EIW69048.1 - 0.092 12.5 0.3 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO FtsK_SpoIIIE PF01580.13 EIW69048.1 - 0.11 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.9 EIW69048.1 - 0.12 12.1 0.1 1.7 8.3 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SNARE PF05739.14 EIW69049.1 - 2.9e-13 49.2 7.6 2.9e-13 49.2 5.3 2.4 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EIW69049.1 - 0.0036 17.4 2.9 0.0036 17.4 2.0 2.4 2 0 0 2 2 2 1 Syntaxin TB2_DP1_HVA22 PF03134.14 EIW69049.1 - 0.028 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Adaptin_binding PF10199.4 EIW69049.1 - 0.039 14.2 2.0 0.24 11.7 0.0 2.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Zip PF02535.17 EIW69049.1 - 0.067 12.1 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MCPsignal PF00015.16 EIW69049.1 - 0.21 11.0 14.0 0.022 14.3 3.3 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.1 EIW69049.1 - 0.21 11.6 17.7 0.046 13.7 7.3 2.3 2 1 0 2 2 2 0 Syntaxin-like protein VIT1 PF01988.14 EIW69049.1 - 0.42 10.0 6.4 6.8 6.1 1.5 2.2 2 0 0 2 2 2 0 VIT family DUF3810 PF12725.2 EIW69049.1 - 0.42 9.4 7.7 0.77 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Myb_DNA-bind_3 PF12776.2 EIW69049.1 - 0.6 10.7 7.0 4.9 7.8 1.1 2.9 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3708 PF12501.3 EIW69049.1 - 0.77 9.5 8.0 0.58 9.9 0.4 2.3 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter Kinesin-relat_1 PF12711.2 EIW69049.1 - 1.8 9.0 8.2 0.12 12.8 0.5 2.4 2 1 0 2 2 2 0 Kinesin motor DUF948 PF06103.6 EIW69049.1 - 3.4 7.5 14.7 11 5.9 0.6 3.5 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 EIW69049.1 - 3.6 6.5 19.9 4.6 6.2 6.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4094 PF13334.1 EIW69049.1 - 3.7 7.9 7.0 2.1 8.7 0.1 3.6 1 1 4 5 5 5 0 Domain of unknown function (DUF4094) Sulfatase_C PF14707.1 EIW69049.1 - 4.4 7.6 7.2 4.9 7.4 0.6 2.5 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase HWE_HK PF07536.9 EIW69049.1 - 5.5 7.4 9.9 5.2 7.5 1.2 3.0 2 1 1 3 3 3 0 HWE histidine kinase Jnk-SapK_ap_N PF09744.4 EIW69049.1 - 7.9 6.4 18.5 0.47 10.4 4.0 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Mer2 PF09074.5 EIW69049.1 - 8.9 6.1 15.3 0.05 13.5 1.0 2.5 2 1 0 2 2 2 0 Mer2 TPR_MLP1_2 PF07926.7 EIW69049.1 - 9.6 5.9 23.9 4.6 6.9 7.2 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pkinase PF00069.20 EIW69050.1 - 8.4e-69 231.6 0.0 9.5e-69 231.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69050.1 - 2.6e-33 115.2 0.0 3.5e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW69050.1 - 0.00031 19.8 0.0 0.00079 18.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIW69050.1 - 0.032 13.2 0.1 0.063 12.3 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclin PF08613.6 EIW69051.1 - 3.8e-36 124.7 0.0 7.3e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin DUF938 PF06080.7 EIW69052.1 - 5.7e-22 78.2 0.0 2.7e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Adeno_E3_CR2 PF02439.10 EIW69053.1 - 0.084 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 EIW69053.1 - 0.09 12.4 0.1 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 EIW69053.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 EIW69053.1 - 1.3 8.4 4.1 0.69 9.2 0.3 2.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Fork_head PF00250.13 EIW69055.1 - 6.2e-20 71.0 0.0 1.7e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EIW69055.1 - 0.00014 21.8 0.1 0.00062 19.8 0.0 2.1 2 0 0 2 2 2 1 FHA domain HECT_2 PF09814.4 EIW69056.1 - 1.2e-39 136.0 0.0 1.8e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Peptidase_S9 PF00326.16 EIW69056.1 - 0.12 11.6 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family TPR_12 PF13424.1 EIW69057.1 - 7.1e-11 41.8 7.5 0.0065 16.3 0.1 4.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW69057.1 - 9.5e-08 31.2 9.7 0.12 12.2 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW69057.1 - 2.3e-07 30.2 9.8 0.15 12.0 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIW69057.1 - 1.3e-06 27.9 4.8 0.62 9.7 0.0 4.5 4 1 0 4 4 4 2 TPR repeat TPR_7 PF13176.1 EIW69057.1 - 1.6e-05 24.3 2.0 3.3 7.7 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW69057.1 - 1.8e-05 24.1 12.0 0.24 11.0 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW69057.1 - 5.1e-05 23.8 4.3 5.8 7.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW69057.1 - 0.0019 18.6 10.6 6.2 7.7 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIW69057.1 - 0.11 12.7 0.0 22 5.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIW69057.1 - 0.12 12.6 5.9 5.6 7.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIW69057.1 - 0.22 11.4 5.0 9.9 6.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW69057.1 - 0.35 11.4 8.9 2.5 8.7 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 EIW69057.1 - 0.54 10.1 2.4 6.4 6.6 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat IF-2B PF01008.12 EIW69058.1 - 2.8e-56 190.6 0.9 3.5e-55 186.9 0.6 1.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF2600 PF10776.4 EIW69058.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) Dynactin_p62 PF05502.8 EIW69059.1 - 1.3e-73 248.4 8.4 2.5e-69 234.3 5.8 2.1 1 1 0 1 1 1 1 Dynactin p62 family DUF164 PF02591.10 EIW69059.1 - 4 7.3 11.8 1.5 8.7 4.1 3.1 2 1 1 3 3 3 0 Putative zinc ribbon domain E1-E2_ATPase PF00122.15 EIW69060.1 - 1.2e-66 224.0 1.2 1.2e-66 224.0 0.9 2.9 3 1 1 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIW69060.1 - 2e-47 161.0 7.7 2e-47 161.0 5.3 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIW69060.1 - 1.8e-33 116.7 0.0 2e-32 113.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW69060.1 - 1.1e-20 73.4 0.0 2.2e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIW69060.1 - 2e-19 68.8 0.2 2.7e-18 65.1 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EIW69060.1 - 9.6e-18 65.0 0.7 2.7e-17 63.5 0.5 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIW69060.1 - 9.1e-08 31.9 1.5 5.9e-06 26.0 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase VWA_2 PF13519.1 EIW69060.1 - 0.054 13.6 0.3 51 3.9 0.1 3.6 2 1 0 3 3 3 0 von Willebrand factor type A domain Ras PF00071.17 EIW69061.1 - 7.3e-50 168.5 0.1 8.3e-50 168.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW69061.1 - 2.4e-17 63.5 0.0 3.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW69061.1 - 1.6e-05 24.8 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EIW69061.1 - 0.00039 19.7 0.0 0.00043 19.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW69061.1 - 0.0022 17.4 0.0 0.009 15.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EIW69061.1 - 0.024 13.9 0.0 0.47 9.7 0.0 2.5 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 EIW69061.1 - 0.037 13.2 0.1 0.76 8.9 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF258 MBOAT_2 PF13813.1 EIW69062.1 - 1.8e-13 50.3 0.4 1.8e-13 50.3 0.2 3.0 3 0 0 3 3 3 2 Membrane bound O-acyl transferase family AA_permease_2 PF13520.1 EIW69063.1 - 2.7e-35 121.7 37.4 3.8e-35 121.2 25.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW69063.1 - 9.5e-25 86.8 31.9 1.3e-24 86.3 22.1 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM154 PF15102.1 EIW69064.1 - 0.0069 16.0 0.2 0.023 14.4 0.1 1.9 1 0 0 1 1 1 1 TMEM154 protein family UPF0104 PF03706.8 EIW69064.1 - 0.045 13.0 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Neur_chan_memb PF02932.11 EIW69064.1 - 0.13 12.1 0.1 0.24 11.2 0.1 1.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FUSC PF04632.7 EIW69064.1 - 0.23 9.8 1.0 0.33 9.3 0.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CcmD PF04995.9 EIW69064.1 - 0.57 9.9 4.2 1.6 8.5 2.9 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Shisa PF13908.1 EIW69064.1 - 1.1 9.4 4.6 1.2 9.2 0.0 2.8 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Aldo_ket_red PF00248.16 EIW69065.1 - 5.7e-47 159.8 0.0 6.8e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIW69067.1 - 3.1e-46 157.4 0.0 3.7e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OCIA PF07051.6 EIW69067.1 - 0.15 11.4 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) DUF718 PF05336.8 EIW69068.1 - 1.4e-29 101.9 0.2 1.7e-29 101.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Abhydrolase_6 PF12697.2 EIW69069.1 - 4e-31 108.6 0.0 5.7e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW69069.1 - 8.8e-17 61.2 0.0 1.3e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW69069.1 - 4.3e-14 52.6 0.0 1e-12 48.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EIW69069.1 - 1.2e-08 35.4 0.0 1.7e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EIW69069.1 - 4.1e-08 33.1 0.0 6.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EIW69069.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 EIW69069.1 - 0.00031 20.1 0.0 0.001 18.4 0.0 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.2 EIW69069.1 - 0.00096 18.1 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.8 EIW69069.1 - 0.001 17.4 0.0 0.0074 14.6 0.0 2.0 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.6 EIW69069.1 - 0.0018 17.0 0.0 0.0029 16.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase DUF915 PF06028.6 EIW69069.1 - 0.0057 15.7 0.0 0.011 14.7 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.7 EIW69069.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2424 PF10340.4 EIW69069.1 - 0.069 11.7 0.0 0.088 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EIW69069.1 - 0.071 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EIW69069.1 - 0.11 12.1 0.1 0.26 10.9 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 3) DUF2048 PF09752.4 EIW69069.1 - 0.12 11.2 0.0 5.8 5.6 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2048) LCAT PF02450.10 EIW69069.1 - 0.14 11.1 0.1 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HIT PF01230.18 EIW69071.1 - 4.9e-20 71.8 0.0 6.6e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EIW69071.1 - 1.9e-05 24.8 0.0 2.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Peptidase_M42 PF05343.9 EIW69071.1 - 0.1 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase TFIIA PF03153.8 EIW69072.1 - 6.7 6.4 22.9 18 5.0 15.9 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Transket_pyr PF02779.19 EIW69073.1 - 2.4e-57 193.3 0.0 3.5e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EIW69073.1 - 4.3e-41 140.5 0.0 6.8e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Lactamase_B PF00753.22 EIW69074.1 - 1e-09 38.3 0.6 2.2e-09 37.2 0.4 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW69074.1 - 1.2e-09 38.0 1.8 2.7e-09 36.8 1.1 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EIW69075.1 - 2.4e-11 43.5 0.0 1.1e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIW69075.1 - 0.00083 19.0 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EIW69075.1 - 0.063 12.9 0.0 0.22 11.2 0.0 2.0 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF1364 PF07102.7 EIW69075.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) DUF2567 PF10821.3 EIW69076.1 - 0.0056 16.2 0.1 0.0075 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2567) DUF2374 PF09574.5 EIW69076.1 - 0.14 11.8 0.4 0.27 10.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) LysM PF01476.15 EIW69077.1 - 1.5e-16 59.9 0.1 6.2e-07 29.1 0.0 2.6 3 0 0 3 3 3 2 LysM domain IGFBP PF00219.13 EIW69077.1 - 0.46 11.0 2.6 5.4 7.6 0.0 2.6 3 0 0 3 3 3 0 Insulin-like growth factor binding protein Carboxyl_trans PF01039.17 EIW69078.1 - 1.4e-22 79.7 0.0 1.7e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Transposase_24 PF03004.9 EIW69078.1 - 0.029 14.2 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) PAN_1 PF00024.21 EIW69079.1 - 8.9e-06 25.3 3.0 9.1e-06 25.3 1.4 1.6 1 1 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EIW69079.1 - 0.00017 21.2 0.6 0.00017 21.2 0.4 2.4 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.7 EIW69079.1 - 0.0015 18.1 1.7 0.0015 18.1 1.2 1.9 2 0 0 2 2 2 1 PAN-like domain Catalase PF00199.14 EIW69080.1 - 2e-161 536.9 0.1 2.7e-161 536.5 0.1 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EIW69080.1 - 4.1e-17 61.7 0.4 8.9e-17 60.7 0.3 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EIW69080.1 - 1.8e-05 24.2 0.1 4.6e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family Pertussis_S2S3 PF02918.10 EIW69081.1 - 0.026 14.2 0.1 0.05 13.3 0.1 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain SOG2 PF10428.4 EIW69081.1 - 1.4 7.5 9.7 1.2 7.7 4.8 1.8 2 0 0 2 2 2 0 RAM signalling pathway protein Ras PF00071.17 EIW69082.1 - 2.9e-44 150.2 0.0 3.4e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW69082.1 - 1.4e-11 44.8 0.0 1.9e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EIW69082.1 - 3.7e-05 23.2 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EIW69082.1 - 0.00045 19.4 0.0 0.00055 19.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Zn_clus PF00172.13 EIW69083.1 - 1.2e-08 34.7 10.3 1.9e-08 34.0 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.18 EIW69084.1 - 6.7e-110 367.2 0.0 7.9e-110 367.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW69084.1 - 3.9e-11 43.1 0.1 9.5e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW69084.1 - 1.2e-06 28.1 0.0 3e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIW69084.1 - 3.1e-05 24.3 0.0 0.2 12.1 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 EIW69084.1 - 0.032 14.0 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Ribonuc_red_sm PF00268.16 EIW69085.1 - 3.6e-107 357.5 0.8 4.4e-107 357.2 0.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain GTP_EFTU PF00009.22 EIW69086.1 - 1.4e-39 135.5 0.8 1.1e-38 132.6 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EIW69086.1 - 4e-30 103.8 2.7 9.5e-30 102.6 1.9 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EIW69086.1 - 3.1e-13 49.6 6.3 2.6e-06 27.4 0.0 3.5 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW69086.1 - 2.1e-07 30.8 0.2 7.6e-07 29.0 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EIW69086.1 - 9.6e-06 25.1 0.2 0.02 14.3 0.0 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 EIW69086.1 - 0.00028 20.4 4.8 0.0018 17.8 0.6 3.4 3 0 0 3 3 3 1 Elongation factor Tu domain 4 Miro PF08477.8 EIW69086.1 - 0.015 15.8 0.8 0.28 11.6 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein MobB PF03205.9 EIW69086.1 - 0.035 13.8 0.6 0.24 11.1 0.0 2.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EIW69086.1 - 0.044 13.6 0.0 2.4 7.9 0.0 2.5 1 1 1 2 2 2 0 Dynamin family AAA_29 PF13555.1 EIW69086.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aldo_ket_red PF00248.16 EIW69087.1 - 7.4e-32 110.3 0.0 8.5e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Urease_alpha PF00449.15 EIW69088.1 - 1.7e-57 192.7 2.7 4.3e-57 191.5 1.9 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_1 PF01979.15 EIW69088.1 - 3.6e-55 187.9 2.0 6.4e-55 187.1 1.4 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_gamma PF00547.13 EIW69088.1 - 1.2e-41 140.7 0.1 3.8e-41 139.1 0.0 2.0 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 EIW69088.1 - 1.8e-37 127.1 0.0 3.8e-37 126.1 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Amidohydro_5 PF13594.1 EIW69088.1 - 0.00019 21.1 2.5 0.00019 21.1 1.7 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EIW69088.1 - 0.0027 17.0 0.8 0.046 12.9 0.1 2.2 2 0 0 2 2 2 1 Amidohydrolase family Calpain_III PF01067.17 EIW69089.1 - 6.3e-19 68.0 0.0 4.6e-09 36.0 0.0 5.0 3 2 0 3 3 3 3 Calpain large subunit, domain III Kelch_6 PF13964.1 EIW69090.1 - 2.4e-06 27.4 2.8 0.051 13.7 0.1 4.1 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 EIW69090.1 - 0.0096 15.4 2.6 0.15 11.6 0.3 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 EIW69090.1 - 0.16 12.1 0.2 0.16 12.1 0.1 4.7 5 1 0 5 5 5 0 Galactose oxidase, central domain MULE PF10551.4 EIW69091.1 - 2.3e-13 50.1 1.4 1e-10 41.5 0.2 3.6 2 1 0 2 2 2 1 MULE transposase domain UCH PF00443.24 EIW69091.1 - 2.6e-09 36.5 0.0 6.6e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW69091.1 - 0.035 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TFIIF_alpha PF05793.7 EIW69092.1 - 6.1 5.0 12.6 9.1 4.5 8.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_delta_4 PF04081.8 EIW69093.1 - 3.2e-22 79.1 0.1 4.1e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Cellulase PF00150.13 EIW69095.1 - 7e-12 45.1 0.3 1.5e-09 37.4 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 EIW69095.1 - 0.015 14.6 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 NTF2 PF02136.15 EIW69096.1 - 2.4e-32 111.7 0.0 2.6e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF3872 PF12988.2 EIW69096.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) AAA_18 PF13238.1 EIW69097.1 - 3.4e-24 85.5 0.0 6.4e-24 84.7 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIW69097.1 - 5.9e-11 43.2 0.0 8.2e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EIW69097.1 - 0.00055 19.4 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.1 EIW69097.1 - 0.0013 18.4 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EIW69097.1 - 0.0018 18.5 0.0 0.004 17.3 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EIW69097.1 - 0.0037 17.2 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EIW69097.1 - 0.0097 15.0 0.0 0.024 13.7 0.0 1.6 2 0 0 2 2 2 1 KaiC Dna2 PF08696.6 EIW69097.1 - 0.012 14.9 0.2 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 DNA replication factor Dna2 AAA_22 PF13401.1 EIW69097.1 - 0.014 15.5 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIW69097.1 - 0.031 14.1 0.2 4.8 7.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain DUF445 PF04286.7 EIW69097.1 - 0.038 13.5 0.1 0.049 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AAA_16 PF13191.1 EIW69097.1 - 0.054 13.4 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 EIW69097.1 - 0.071 12.0 0.2 0.071 12.0 0.2 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EIW69097.1 - 0.082 12.3 0.1 0.23 10.8 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family KTI12 PF08433.5 EIW69097.1 - 0.085 12.0 0.0 0.27 10.3 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Fungal_trans PF04082.13 EIW69098.1 - 1.9e-23 82.6 0.0 3.3e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW69098.1 - 4.3e-09 36.1 13.2 7.8e-09 35.3 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC14 PF15254.1 EIW69099.1 - 0.51 8.6 2.2 0.46 8.8 0.1 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 14 TFIIF_alpha PF05793.7 EIW69100.1 - 4.4 5.5 11.9 6.6 4.9 8.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) JmjC PF02373.17 EIW69101.1 - 3.2e-39 133.7 0.4 8e-39 132.4 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.1 EIW69101.1 - 1.1e-15 57.5 0.5 3.2e-15 56.0 0.3 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 EIW69101.1 - 2.5e-15 55.6 0.4 5e-15 54.7 0.3 1.5 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.1 EIW69101.1 - 2.6e-15 56.3 0.4 6.9e-15 54.9 0.3 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.24 EIW69101.1 - 0.02 14.5 1.2 0.02 14.5 0.8 2.1 2 0 0 2 2 2 0 PHD-finger VWC PF00093.13 EIW69101.1 - 0.034 14.2 3.2 0.051 13.6 0.8 2.2 2 0 0 2 2 2 0 von Willebrand factor type C domain zinc_ribbon_4 PF13717.1 EIW69101.1 - 0.13 12.0 1.5 4.6 7.0 0.1 2.8 1 1 1 2 2 2 0 zinc-ribbon domain Mur_ligase_M PF08245.7 EIW69102.1 - 1.9e-08 34.6 0.0 3.5e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Transp_cyt_pur PF02133.10 EIW69104.1 - 4.5e-67 226.5 46.9 5.5e-67 226.2 32.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Indigoidine_A PF04227.7 EIW69105.1 - 2.2e-109 365.2 0.2 3.4e-109 364.5 0.1 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EIW69105.1 - 2.5e-16 59.6 0.0 1.5e-06 27.5 0.0 3.2 3 0 0 3 3 3 3 pfkB family carbohydrate kinase SEN1_N PF12726.2 EIW69108.1 - 4.1e-117 392.1 1.6 5e-117 391.8 1.1 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EIW69108.1 - 6.8e-67 225.4 0.1 1.3e-66 224.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EIW69108.1 - 3.7e-62 209.2 0.0 5.9e-62 208.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW69108.1 - 7.2e-08 32.0 0.0 2.7e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EIW69108.1 - 1.1e-07 31.6 0.1 0.015 14.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EIW69108.1 - 2.6e-05 23.9 0.1 0.01 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EIW69108.1 - 0.024 13.9 0.0 0.48 9.6 0.0 2.1 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EIW69108.1 - 0.052 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EIW69108.1 - 0.13 12.4 0.1 1.3 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EIW69108.1 - 0.17 12.0 0.9 0.99 9.6 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Spc97_Spc98 PF04130.8 EIW69109.1 - 1.6e-20 73.0 0.1 2.5e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family MRP PF09387.5 EIW69109.1 - 0.015 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP Prp19_bind PF06991.6 EIW69109.1 - 3 7.0 8.5 0.46 9.7 3.1 1.6 2 0 0 2 2 2 0 Splicing factor, Prp19-binding domain PCI PF01399.22 EIW69110.1 - 4.3e-09 36.6 6.9 2.2e-08 34.3 1.8 2.8 2 1 1 3 3 3 2 PCI domain TPR_12 PF13424.1 EIW69110.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat MGDG_synth PF06925.6 EIW69110.1 - 0.095 12.5 0.4 0.2 11.5 0.3 1.5 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase DSPc PF00782.15 EIW69112.1 - 4.8e-34 116.7 0.0 2.2e-23 82.3 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW69112.1 - 0.00062 19.1 0.0 0.063 12.6 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase MFS_1 PF07690.11 EIW69113.1 - 4.8e-51 173.5 17.0 4.8e-51 173.5 11.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW69113.1 - 9e-16 57.4 3.8 9e-16 57.4 2.6 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EIW69113.1 - 3.8e-06 25.3 6.7 7e-06 24.5 3.4 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EIW69113.1 - 9.7e-06 23.9 0.2 0.0001 20.5 0.6 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 EIW69113.1 - 0.018 13.4 15.6 0.68 8.2 0.6 3.6 2 1 0 2 2 2 0 MFS/sugar transport protein MFS_3 PF05977.8 EIW69113.1 - 0.085 10.9 2.3 0.19 9.7 1.6 1.5 1 0 0 1 1 1 0 Transmembrane secretion effector ATG22 PF11700.3 EIW69113.1 - 8.9 4.6 20.4 0.12 10.8 2.6 3.1 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like Spo12 PF05032.7 EIW69114.1 - 1.3e-10 40.7 0.9 2.4e-10 39.8 0.6 1.5 1 0 0 1 1 1 1 Spo12 family Nramp PF01566.13 EIW69115.1 - 9e-91 304.3 20.9 1.3e-90 303.8 14.5 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Ndc1_Nup PF09531.5 EIW69115.1 - 0.11 10.8 1.0 0.2 10.0 0.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CUE PF02845.11 EIW69116.1 - 0.001 18.4 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain SKG6 PF08693.5 EIW69116.1 - 4.7 6.6 5.4 2.3 7.6 0.6 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Aminotran_1_2 PF00155.16 EIW69117.1 - 2.4e-39 135.3 0.0 2.8e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW69117.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DLH PF01738.13 EIW69118.1 - 7.1e-17 61.4 0.1 8.1e-17 61.2 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Spo12 PF05032.7 EIW69119.1 - 0.00061 19.3 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Spo12 family Chorismate_synt PF01264.16 EIW69120.1 - 2.2e-128 427.6 0.0 2.5e-128 427.4 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Hormone_4 PF00220.12 EIW69120.1 - 1 9.1 3.3 3 7.7 2.3 1.8 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain SIP1 PF04938.7 EIW69121.1 - 0.00019 20.8 0.8 0.025 13.9 0.0 3.1 4 0 0 4 4 4 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) MHYT PF03707.11 EIW69122.1 - 0.52 10.4 30.4 0.056 13.5 4.0 4.3 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat OCC1 PF15506.1 EIW69123.1 - 0.086 12.7 0.4 14 5.6 0.1 2.4 2 0 0 2 2 2 0 OCC1 family SlyX PF04102.7 EIW69126.1 - 0.03 14.6 0.5 0.056 13.8 0.3 1.4 1 0 0 1 1 1 0 SlyX ERCC4 PF02732.10 EIW69128.1 - 1.1e-22 80.3 0.0 3.5e-22 78.6 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain RNase_H PF00075.19 EIW69129.1 - 2.6e-09 37.4 0.1 4.8e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EIW69129.1 - 0.024 14.9 0.0 0.1 12.8 0.0 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase YqeY PF09424.5 EIW69130.1 - 4.7e-20 71.9 0.0 5.4e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Yqey-like protein NIF PF03031.13 EIW69131.1 - 6.1e-09 35.7 0.0 0.0008 19.1 0.0 2.7 2 1 0 2 2 2 2 NLI interacting factor-like phosphatase DUF2404 PF10296.4 EIW69132.1 - 6.6e-06 26.1 0.0 1.9e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) KKLCAg1 PF15204.1 EIW69132.1 - 0.031 14.3 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 FabA PF07977.8 EIW69132.1 - 0.1 12.0 0.0 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 FabA-like domain Cyt-b5 PF00173.23 EIW69133.1 - 3.3e-26 90.8 0.0 4.3e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gemini_mov PF01708.11 EIW69133.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Geminivirus putative movement protein Ribosomal_L7Ae PF01248.21 EIW69134.1 - 9.3e-19 66.7 0.7 1.7e-18 65.9 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L38e PF01781.13 EIW69135.1 - 8.1e-30 102.3 2.8 8.9e-30 102.2 1.9 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TAF4 PF05236.9 EIW69136.1 - 6.7e-12 45.2 8.8 1.3e-05 24.5 4.1 2.3 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family SNF2_N PF00176.18 EIW69137.1 - 4e-80 268.8 0.1 6.2e-80 268.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EIW69137.1 - 4.1e-40 136.1 1.8 1.7e-39 134.1 0.2 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EIW69137.1 - 3.1e-30 104.8 2.3 3.1e-30 104.8 1.6 3.9 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EIW69137.1 - 4.2e-14 52.1 0.0 1.3e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW69137.1 - 1.8e-07 31.1 0.5 3.1e-06 27.1 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIW69137.1 - 1.7e-06 27.6 0.4 2.4e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.1 EIW69137.1 - 6.8e-05 22.9 0.7 6.8e-05 22.9 0.5 3.5 2 0 0 2 2 2 1 DNA-binding domain AAA_14 PF13173.1 EIW69137.1 - 0.0048 16.7 1.0 0.057 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain DEAD_2 PF06733.10 EIW69137.1 - 0.0067 15.8 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 DUF2587 PF10759.4 EIW69138.1 - 0.021 14.2 0.1 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Dysbindin PF04440.11 EIW69138.1 - 0.06 13.1 3.7 0.19 11.4 2.6 1.8 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) DUF2587 PF10759.4 EIW69139.1 - 0.06 12.7 0.1 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) KA1 PF02149.14 EIW69142.1 - 6.5e-07 28.6 0.1 1.3e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Pkinase PF00069.20 EIW69143.1 - 3.1e-70 236.2 0.0 3.5e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69143.1 - 6.9e-41 140.0 0.0 8.2e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW69143.1 - 3.4e-07 29.5 0.0 4.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIW69143.1 - 1.8e-05 24.1 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIW69143.1 - 0.0095 15.6 0.2 0.019 14.6 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Phage_T7_Capsid PF05396.6 EIW69143.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Phage T7 capsid assembly protein YrbL-PhoP_reg PF10707.4 EIW69143.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EIW69143.1 - 0.015 14.3 0.1 0.03 13.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec39 PF08314.6 EIW69144.1 - 6.1e-35 120.3 0.2 7.9e-29 100.1 0.0 2.5 2 1 0 2 2 2 2 Secretory pathway protein Sec39 Pex2_Pex12 PF04757.9 EIW69145.1 - 2.5e-19 69.6 3.5 5.4e-19 68.5 2.4 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.1 EIW69145.1 - 4.7e-09 35.8 2.3 7.2e-09 35.2 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW69145.1 - 1.8e-07 30.7 1.3 2.8e-07 30.1 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW69145.1 - 1.8e-07 30.8 3.8 3.2e-07 30.0 2.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW69145.1 - 0.00035 20.5 3.7 0.0007 19.5 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW69145.1 - 0.00063 19.3 1.3 0.0012 18.4 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EIW69145.1 - 0.013 15.0 0.6 0.024 14.1 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EIW69145.1 - 0.046 13.3 2.0 0.077 12.5 1.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EIW69145.1 - 0.047 13.4 1.1 0.11 12.2 0.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EIW69145.1 - 0.4 10.4 5.8 0.1 12.3 1.4 2.1 2 1 0 2 2 2 0 RING-type zinc-finger Hist_deacetyl PF00850.14 EIW69146.1 - 2.2e-80 270.2 0.0 2.6e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain DUF2800 PF10926.3 EIW69146.1 - 0.017 14.2 0.0 0.091 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) Beta_helix PF13229.1 EIW69147.1 - 5.6e-13 48.9 6.5 6.6e-08 32.4 0.0 2.3 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.8 EIW69147.1 - 0.00042 19.5 0.2 0.0048 16.0 0.0 2.2 2 1 0 2 2 2 1 Periplasmic copper-binding protein (NosD) adh_short PF00106.20 EIW69148.1 - 1.1e-30 106.7 0.1 1.5e-30 106.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW69148.1 - 2e-17 63.4 0.1 3.7e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW69148.1 - 4.4e-09 36.4 0.0 6.1e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIW69148.1 - 4.9e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW69148.1 - 0.0043 16.5 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW69148.1 - 0.14 10.9 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain BCNT PF07572.7 EIW69149.1 - 5.7e-21 74.2 2.2 5.7e-21 74.2 1.6 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development CPSF73-100_C PF11718.3 EIW69149.1 - 0.044 13.1 3.9 0.025 13.9 1.1 1.7 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term TSGP1 PF07771.6 EIW69149.1 - 6.2 6.7 8.4 0.28 11.0 0.4 2.4 2 1 0 2 2 2 0 Tick salivary peptide group 1 Metallophos PF00149.23 EIW69150.1 - 1.1e-12 47.7 0.4 7.2e-12 45.1 0.3 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW69150.1 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.6 EIW69150.1 - 0.14 10.1 0.6 0.36 8.8 0.0 1.8 2 1 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase Maf PF02545.9 EIW69151.1 - 2.8e-38 131.0 0.0 5.5e-37 126.7 0.0 2.0 1 1 0 1 1 1 1 Maf-like protein DRIM PF07539.7 EIW69152.1 - 2.3e-45 153.4 0.0 1.3e-44 150.9 0.0 2.5 1 0 0 1 1 1 1 Down-regulated in metastasis BSP_II PF05432.6 EIW69152.1 - 4.3 6.5 5.0 0.64 9.2 0.1 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Complex1_LYR_1 PF13232.1 EIW69153.1 - 0.00055 20.0 2.3 0.00076 19.6 1.6 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EIW69153.1 - 0.0014 18.3 0.2 0.0014 18.3 0.2 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DRP PF06044.7 EIW69153.1 - 0.14 11.0 0.1 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Dam-replacing family COX17 PF05051.8 EIW69154.1 - 2.5e-20 72.2 1.4 2.5e-20 72.2 1.0 1.4 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) GPI2 PF06432.6 EIW69155.1 - 2.8e-62 210.6 0.0 3.3e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Spc7 PF08317.6 EIW69157.1 - 0.0056 15.3 8.1 0.0056 15.3 5.6 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein V_ATPase_I PF01496.14 EIW69157.1 - 0.01 13.7 8.6 0.016 13.1 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Thioredoxin_2 PF13098.1 EIW69157.1 - 0.047 13.8 0.3 5.4 7.2 0.3 2.9 2 1 0 2 2 2 0 Thioredoxin-like domain AAA_13 PF13166.1 EIW69157.1 - 0.063 11.7 18.2 0.13 10.6 12.6 1.5 1 1 0 1 1 1 0 AAA domain WEMBL PF05701.6 EIW69157.1 - 0.097 11.1 34.9 1.7 7.0 24.2 2.2 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 EIW69157.1 - 0.16 9.6 30.6 0.28 8.8 20.9 1.5 1 1 0 1 1 1 0 Myosin tail IncA PF04156.9 EIW69157.1 - 0.38 10.3 27.8 29 4.1 19.4 3.1 1 1 0 1 1 1 0 IncA protein UPF0242 PF06785.6 EIW69157.1 - 0.8 8.3 13.9 1.2 7.6 9.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF904 PF06005.7 EIW69157.1 - 1 9.6 17.6 15 5.9 0.1 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Filament PF00038.16 EIW69157.1 - 1.3 8.3 30.0 7.3 5.9 20.9 2.2 1 1 0 1 1 1 0 Intermediate filament protein TMF_TATA_bd PF12325.3 EIW69157.1 - 3.3 7.4 22.5 6.1 6.5 0.2 3.7 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.6 EIW69157.1 - 5.4 4.4 11.8 8.9 3.7 8.2 1.2 1 0 0 1 1 1 0 Prominin DUF972 PF06156.8 EIW69157.1 - 5.5 7.3 17.1 3.4 8.0 3.2 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 EIW69157.1 - 7 6.4 28.0 0.48 10.2 11.9 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EIW69157.1 - 8.5 5.4 9.3 3 6.9 1.4 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein TFIIF_alpha PF05793.7 EIW69158.1 - 0.096 11.0 2.4 0.18 10.1 1.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Phage_integrase PF00589.17 EIW69161.1 - 1.3e-05 24.9 0.1 2.4e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Phage integrase family DUF3435 PF11917.3 EIW69161.1 - 2.3e-05 23.3 0.1 0.00034 19.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) DUF747 PF05346.6 EIW69162.1 - 1.2e-112 376.2 0.1 1.6e-112 375.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Lin-8 PF03353.10 EIW69162.1 - 0.17 11.1 2.1 0.19 10.9 0.6 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist NDUF_B4 PF07225.7 EIW69163.1 - 1.9e-05 24.4 0.0 2.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-patch PF01585.18 EIW69164.1 - 2.5e-12 46.3 1.5 2.5e-12 46.3 1.0 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EIW69164.1 - 2.8e-05 23.8 1.2 7e-05 22.5 0.8 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_6 PF14259.1 EIW69164.1 - 0.0028 17.5 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 EIW69164.1 - 0.021 14.0 0.1 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region RRM_1 PF00076.17 EIW69164.1 - 0.024 14.2 0.0 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 EIW69164.1 - 0.055 13.6 0.1 0.096 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF4279 PF14106.1 EIW69165.1 - 0.0088 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4279) ubiquitin PF00240.18 EIW69166.1 - 5.7e-16 57.6 0.0 1.1e-15 56.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIW69166.1 - 4.4e-08 32.6 0.0 7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIW69166.1 - 0.002 18.2 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EIW69166.1 - 0.058 13.6 0.1 0.19 11.9 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain YukD PF08817.5 EIW69166.1 - 0.098 13.2 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Shugoshin_C PF07557.6 EIW69167.1 - 8e-09 34.8 2.8 8e-09 34.8 2.0 2.6 3 0 0 3 3 3 1 Shugoshin C terminus DUF3375 PF11855.3 EIW69167.1 - 0.029 13.1 2.3 0.061 12.0 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Mob1_phocein PF03637.12 EIW69168.1 - 7.9e-74 247.0 0.2 9.2e-74 246.8 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family Methyltransf_23 PF13489.1 EIW69169.1 - 1.7e-09 37.6 0.0 3.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW69169.1 - 0.059 13.8 0.0 0.13 12.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain zf-C3HC4_2 PF13923.1 EIW69170.1 - 5e-10 39.2 13.9 6.4e-10 38.8 7.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW69170.1 - 6.9e-09 35.2 8.2 6.9e-09 35.2 5.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW69170.1 - 5.1e-08 32.6 14.5 6.3e-08 32.3 6.8 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EIW69170.1 - 7.8e-08 32.0 10.1 3.8e-07 29.8 5.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW69170.1 - 1.5e-07 30.9 10.2 2.3e-07 30.3 4.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW69170.1 - 8.4e-07 28.6 8.4 8.4e-07 28.6 5.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 EIW69170.1 - 1.3e-05 24.8 6.0 1.9e-05 24.3 2.6 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EIW69170.1 - 1.6e-05 24.5 7.3 1.6e-05 24.5 5.1 1.9 2 0 0 2 2 1 1 RING-type zinc-finger SAP PF02037.22 EIW69170.1 - 0.0021 17.4 0.0 0.0048 16.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain U-box PF04564.10 EIW69170.1 - 0.0029 17.5 0.0 0.0098 15.8 0.0 1.9 2 0 0 2 2 1 1 U-box domain Arteri_nucleo PF01481.11 EIW69170.1 - 0.041 13.9 0.4 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein DUF1136 PF06582.7 EIW69170.1 - 0.075 12.7 0.4 0.21 11.3 0.0 1.9 2 0 0 2 2 1 0 Repeat of unknown function (DUF1136) Ebola_NP PF05505.7 EIW69170.1 - 0.13 10.2 1.7 0.16 9.9 1.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein zf-RING_4 PF14570.1 EIW69170.1 - 0.41 10.2 8.2 1.8 8.2 4.2 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EIW69170.1 - 0.66 10.1 8.4 0.29 11.2 3.2 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger zf-Nse PF11789.3 EIW69170.1 - 2.2 7.8 8.2 0.71 9.4 3.4 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 EIW69170.1 - 4.9 7.0 9.7 10 6.0 5.0 2.6 2 1 0 2 2 2 0 Double zinc ribbon Glyco_transf_21 PF13506.1 EIW69171.1 - 7.6e-20 70.9 1.1 5.4e-09 35.5 0.0 3.5 3 1 1 4 4 4 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EIW69171.1 - 4.2e-18 65.9 0.0 6.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIW69171.1 - 5.2e-05 22.9 0.0 8.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Sec8_exocyst PF04048.9 EIW69172.1 - 5.2e-16 58.5 0.0 1.8e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain FAA_hydrolase_N PF09298.6 EIW69172.1 - 0.073 13.0 2.5 13 5.8 0.4 3.8 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal DUF2421 PF10334.4 EIW69174.1 - 2.2e-51 174.7 0.0 8.6e-51 172.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 EIW69174.1 - 1.9e-42 145.6 1.0 2.9e-42 145.0 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2422) DnaJ PF00226.26 EIW69175.1 - 1e-21 76.3 3.9 9.2e-21 73.3 1.3 2.6 2 0 0 2 2 2 1 DnaJ domain SRR1 PF07985.7 EIW69175.1 - 5.6e-12 45.3 0.0 1.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 SRR1 zf-C2H2_jaz PF12171.3 EIW69175.1 - 1.4e-09 37.7 0.2 3.4e-09 36.5 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW69175.1 - 1.9e-06 27.8 0.2 4.1e-06 26.7 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIW69175.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) ARGLU PF15346.1 EIW69175.1 - 4.1 7.1 26.5 1.2 8.9 3.3 2.7 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 IncA PF04156.9 EIW69175.1 - 7.4 6.1 7.3 1.6 8.2 1.3 2.5 2 0 0 2 2 2 0 IncA protein Ras PF00071.17 EIW69176.1 - 2.4e-35 121.3 0.4 2.8e-35 121.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW69176.1 - 1.5e-23 83.5 0.2 1.4e-22 80.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIW69176.1 - 1.6e-08 33.9 0.1 2.2e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW69176.1 - 2.7e-07 29.9 0.3 3.4e-07 29.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW69176.1 - 0.00077 18.9 0.1 0.0044 16.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW69176.1 - 0.0075 16.2 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EIW69176.1 - 0.025 14.0 0.4 0.1 12.0 0.3 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 EIW69176.1 - 0.04 12.6 1.7 0.11 11.2 0.0 1.9 1 1 1 2 2 2 0 G-protein alpha subunit SRPRB PF09439.5 EIW69176.1 - 0.052 12.7 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 EIW69180.1 - 8.7e-36 123.0 0.0 1.7e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW69180.1 - 2.6e-05 24.3 0.0 0.01 15.9 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EIW69180.1 - 0.00037 20.5 9.8 0.00042 20.3 0.6 4.3 3 2 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.7 EIW69180.1 - 0.0017 17.4 0.0 0.0036 16.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIW69180.1 - 0.002 17.8 0.4 0.0095 15.6 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EIW69180.1 - 0.0027 17.4 0.0 0.012 15.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EIW69180.1 - 0.011 15.1 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 EIW69180.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW69180.1 - 0.013 16.3 0.1 0.059 14.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIW69180.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW69180.1 - 0.053 13.8 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EIW69180.1 - 0.056 12.8 0.4 0.5 9.7 0.3 2.3 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EIW69180.1 - 0.069 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EIW69180.1 - 0.072 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EIW69180.1 - 0.086 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 EIW69180.1 - 0.1 11.9 0.0 1.2 8.4 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain AAA_28 PF13521.1 EIW69180.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EIW69180.1 - 0.24 10.5 0.1 0.49 9.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 EIW69180.1 - 0.25 11.5 0.0 0.68 10.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase adh_short PF00106.20 EIW69181.1 - 4.6e-13 49.4 0.0 7.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW69181.1 - 2e-06 27.5 0.0 5.3e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIW69181.1 - 0.0027 17.4 0.1 0.0049 16.6 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EIW69181.1 - 0.096 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EIW69181.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family OB_NTP_bind PF07717.11 EIW69182.1 - 7.6e-29 99.8 0.0 1.7e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EIW69182.1 - 2e-27 95.1 0.3 6.8e-27 93.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIW69182.1 - 2.1e-11 43.5 0.0 5.4e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EIW69182.1 - 8.9e-08 32.1 0.4 2e-07 31.0 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EIW69182.1 - 1.7e-05 24.3 0.1 3.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EIW69182.1 - 0.00022 20.1 0.0 0.0013 17.7 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 EIW69182.1 - 0.00054 20.1 0.0 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW69182.1 - 0.0097 15.6 0.1 0.027 14.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIW69182.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIW69182.1 - 0.022 14.8 0.0 0.078 13.0 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 EIW69182.1 - 0.038 13.8 0.0 0.24 11.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EIW69182.1 - 0.039 13.1 0.0 0.097 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 EIW69182.1 - 0.056 13.2 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EIW69182.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 EIW69182.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EIW69182.1 - 0.12 11.5 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 KaiC Miro PF08477.8 EIW69182.1 - 0.12 12.8 0.1 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein DDE_1 PF03184.14 EIW69183.1 - 4.9e-20 71.6 0.0 7.5e-19 67.7 0.0 2.0 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.1 EIW69185.1 - 1.5e-08 34.5 0.3 3.4e-07 30.0 0.2 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.1 EIW69185.1 - 0.00011 21.6 0.1 0.0003 20.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EIW69185.1 - 0.00016 21.7 0.0 0.00036 20.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EIW69185.1 - 0.0023 18.6 0.0 0.0058 17.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EIW69185.1 - 0.06 13.4 0.0 0.5 10.4 0.0 2.3 2 0 0 2 2 2 0 Transposase HMGL-like PF00682.14 EIW69186.1 - 3.3e-59 200.4 0.0 4.4e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EIW69186.1 - 8.3e-24 83.8 0.0 3.5e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain SHR3_chaperone PF08229.6 EIW69187.1 - 2.6e-18 65.6 0.3 1.1e-17 63.6 0.2 1.7 1 1 0 1 1 1 1 ER membrane protein SH3 DUF1624 PF07786.7 EIW69187.1 - 0.094 12.0 2.2 0.066 12.5 0.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1624) IGPD PF00475.13 EIW69188.1 - 1.1e-61 206.8 0.3 1.5e-61 206.4 0.2 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase PMEI PF04043.10 EIW69189.1 - 0.025 14.5 0.5 0.092 12.6 0.0 2.1 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Cohesin_load PF10345.4 EIW69189.1 - 0.11 10.7 0.1 0.26 9.4 0.0 1.6 1 1 0 1 1 1 0 Cohesin loading factor Ribosomal_S8 PF00410.14 EIW69190.1 - 9.4e-13 48.1 0.0 1.1e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S8 Bot1p PF12298.3 EIW69191.1 - 6.1e-17 62.0 0.1 1.1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF563 PF04577.9 EIW69191.1 - 1.8e-09 37.8 0.0 6.3e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) PTPA PF03095.10 EIW69192.1 - 2.7e-111 371.5 0.0 3.1e-111 371.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Lipase_GDSL_2 PF13472.1 EIW69193.1 - 1.1e-23 84.2 0.0 1.4e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIW69193.1 - 2.5e-23 83.1 0.0 3.2e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LIM PF00412.17 EIW69194.1 - 2.9e-36 123.3 25.0 3.4e-15 55.8 2.0 4.3 4 0 0 4 4 4 4 LIM domain DUF99 PF01949.11 EIW69194.1 - 0.22 10.5 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF99 Mut7-C PF01927.11 EIW69194.1 - 0.8 9.6 9.6 0.78 9.6 0.8 2.3 2 0 0 2 2 2 0 Mut7-C RNAse domain DUF3455 PF11937.3 EIW69195.1 - 4.6e-27 95.0 0.1 5.4e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Atg14 PF10186.4 EIW69196.1 - 6.7e-33 113.9 7.9 7.7e-23 80.8 0.0 2.1 1 1 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 SH3_1 PF00018.23 EIW69197.1 - 1e-09 37.6 0.0 1.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW69197.1 - 1.9e-09 36.9 0.0 5.4e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EIW69197.1 - 3e-06 26.6 0.0 5.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EIW69197.1 - 0.0051 16.9 0.0 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain Dor1 PF04124.7 EIW69198.1 - 4.6e-67 225.8 0.5 5.7e-67 225.5 0.3 1.1 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 EIW69198.1 - 9.8e-05 22.1 0.1 0.00022 21.0 0.1 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 EIW69198.1 - 0.011 15.5 0.0 0.035 13.9 0.0 1.9 1 0 0 1 1 1 0 Vps51/Vps67 ILVD_EDD PF00920.16 EIW69199.1 - 1.4e-200 667.1 0.2 1.7e-200 666.8 0.1 1.1 1 0 0 1 1 1 1 Dehydratase family ABC_tran PF00005.22 EIW69200.1 - 8.6e-51 171.8 0.0 2.5e-28 99.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW69200.1 - 4.6e-49 167.2 29.9 8.1e-31 107.4 8.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EIW69200.1 - 2.2e-10 40.1 0.0 5.2e-05 22.5 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW69200.1 - 2e-09 37.8 2.4 0.0072 16.3 0.0 4.4 4 1 0 4 4 3 2 AAA domain AAA_17 PF13207.1 EIW69200.1 - 1.4e-05 25.8 0.7 0.011 16.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EIW69200.1 - 9.4e-05 22.4 0.7 0.0046 16.9 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EIW69200.1 - 0.00011 21.6 0.2 0.054 12.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EIW69200.1 - 0.00017 21.0 0.7 0.062 12.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 EIW69200.1 - 0.00046 19.7 0.1 1.5 8.3 0.0 2.9 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EIW69200.1 - 0.0013 19.0 0.5 0.49 10.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EIW69200.1 - 0.0014 18.5 1.8 0.26 11.2 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EIW69200.1 - 0.0032 17.8 4.9 0.041 14.1 0.0 2.6 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 EIW69200.1 - 0.0033 17.9 2.5 1 9.9 0.1 2.7 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EIW69200.1 - 0.0055 15.9 0.1 0.4 9.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ArgK PF03308.11 EIW69200.1 - 0.033 12.9 0.7 0.43 9.3 0.0 2.3 2 0 0 2 2 2 0 ArgK protein T2SE PF00437.15 EIW69200.1 - 0.054 12.3 0.0 3.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.4 EIW69200.1 - 0.058 11.9 1.0 4.6 5.7 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 EIW69200.1 - 0.061 12.7 0.4 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.4 EIW69200.1 - 0.087 11.3 1.4 6.3 5.2 0.0 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 EIW69200.1 - 0.11 11.5 0.3 4.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.12 EIW69200.1 - 0.14 11.7 0.7 8 5.9 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 EIW69200.1 - 0.17 10.7 0.3 7 5.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.1 EIW69200.1 - 0.23 11.6 0.8 18 5.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 EIW69200.1 - 0.25 10.9 1.3 21 4.5 0.0 3.2 4 0 0 4 4 4 0 AAA domain MobB PF03205.9 EIW69200.1 - 0.3 10.7 1.8 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 EIW69200.1 - 0.41 9.0 0.6 0.86 7.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EIW69200.1 - 0.66 9.7 3.7 0.49 10.2 0.2 2.5 3 0 0 3 3 3 0 Dynamin family cobW PF02492.14 EIW69200.1 - 0.82 9.0 2.3 1.5 8.2 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EIW69200.1 - 1.4 8.6 4.1 3 7.5 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Chitin_synth_2 PF03142.10 EIW69201.1 - 1.7e-277 921.0 0.2 2.1e-277 920.7 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIW69201.1 - 1.4e-17 64.0 1.8 4.8e-17 62.3 1.3 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW69201.1 - 3.9e-14 53.0 0.0 1.3e-13 51.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIW69201.1 - 2e-05 24.2 0.3 0.00011 21.9 0.1 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EIW69201.1 - 9.2e-05 21.7 0.0 0.0096 15.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 IBN_N PF03810.14 EIW69204.1 - 4.5e-10 39.3 0.4 4.2e-05 23.3 0.1 2.8 2 0 0 2 2 2 2 Importin-beta N-terminal domain GCD14 PF08704.5 EIW69205.1 - 6.2e-82 274.7 0.0 4.4e-76 255.6 0.0 2.1 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EIW69205.1 - 1.9e-05 24.2 0.0 3.5e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW69205.1 - 4.3e-05 23.1 0.0 7.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EIW69205.1 - 0.00024 21.6 0.0 0.0005 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW69205.1 - 0.038 13.0 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EIW69205.1 - 0.051 12.5 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EIW69205.1 - 0.061 13.3 0.0 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EIW69206.1 - 1.5e-54 184.8 0.0 1.8e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69206.1 - 8.3e-37 126.6 0.0 1.1e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW69206.1 - 2.3e-08 33.3 0.0 2.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW69206.1 - 0.0042 16.8 0.1 0.033 13.9 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EIW69206.1 - 0.064 12.5 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EIW69206.1 - 0.093 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EIW69206.1 - 0.097 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Prefoldin_2 PF01920.15 EIW69207.1 - 1.6e-22 79.2 14.2 1.9e-22 79.0 9.2 1.6 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EIW69207.1 - 0.0031 17.2 5.2 0.0063 16.2 3.6 1.5 1 1 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 EIW69207.1 - 0.015 14.9 19.2 0.023 14.3 13.3 1.3 1 1 0 1 1 1 0 IncA protein DUF1104 PF06518.6 EIW69207.1 - 0.027 14.6 0.6 0.027 14.6 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF1664 PF07889.7 EIW69207.1 - 0.041 13.6 7.9 0.27 11.0 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 EIW69207.1 - 0.049 13.5 11.2 0.044 13.6 1.4 2.1 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spore_YpjB PF09577.5 EIW69207.1 - 0.056 13.0 3.8 0.12 11.9 1.2 1.9 1 1 1 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Occludin_ELL PF07303.8 EIW69207.1 - 0.064 13.9 9.6 0.36 11.5 1.6 2.1 2 0 0 2 2 2 0 Occludin homology domain Prefoldin PF02996.12 EIW69207.1 - 0.066 12.8 13.1 0.036 13.7 3.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF4164 PF13747.1 EIW69207.1 - 0.072 13.2 11.3 0.22 11.6 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF607 PF04678.8 EIW69207.1 - 0.089 12.7 5.1 0.047 13.6 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF607 NPV_P10 PF05531.7 EIW69207.1 - 0.11 12.8 7.0 0.2 11.8 0.5 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 EIW69207.1 - 0.11 12.3 12.7 0.033 14.0 1.6 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Transcrip_act PF04949.8 EIW69207.1 - 0.11 12.1 4.5 3.8 7.1 0.9 2.1 2 0 0 2 2 2 0 Transcriptional activator Filament PF00038.16 EIW69207.1 - 0.14 11.6 12.3 0.082 12.3 2.3 2.0 2 0 0 2 2 2 0 Intermediate filament protein Macoilin PF09726.4 EIW69207.1 - 0.14 10.3 10.9 0.16 10.2 7.6 1.1 1 0 0 1 1 1 0 Transmembrane protein AKAP7_NLS PF10469.4 EIW69207.1 - 0.16 11.6 1.9 0.32 10.6 0.1 1.9 1 1 1 2 2 2 0 AKAP7 2'5' RNA ligase-like domain Tropomyosin_1 PF12718.2 EIW69207.1 - 0.16 11.7 16.0 0.48 10.2 3.6 2.1 2 0 0 2 2 2 0 Tropomyosin like MscS_porin PF12795.2 EIW69207.1 - 0.16 11.2 17.6 0.71 9.1 3.6 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EIW69207.1 - 0.18 10.9 2.0 6.6 5.8 0.3 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein YPEB PF14620.1 EIW69207.1 - 0.18 10.7 10.6 0.14 11.1 2.4 2.0 1 1 1 2 2 2 0 YpeB sporulation AAA_23 PF13476.1 EIW69207.1 - 0.27 11.5 13.2 0.34 11.2 9.2 1.1 1 0 0 1 1 1 0 AAA domain ApoO PF09769.4 EIW69207.1 - 0.27 10.9 3.8 1.9 8.2 2.6 1.9 1 1 0 1 1 1 0 Apolipoprotein O Laminin_II PF06009.7 EIW69207.1 - 0.28 10.9 7.9 0.11 12.1 0.9 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF883 PF05957.8 EIW69207.1 - 0.38 11.1 4.2 1 9.8 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) WEMBL PF05701.6 EIW69207.1 - 0.4 9.0 15.1 1.1 7.6 10.5 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Rotamase PF00639.16 EIW69207.1 - 0.44 11.3 2.7 1.6 9.5 0.1 2.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain Tropomyosin PF00261.15 EIW69207.1 - 0.46 9.5 13.0 0.4 9.7 3.0 2.0 2 0 0 2 2 2 0 Tropomyosin IFT57 PF10498.4 EIW69207.1 - 0.5 9.0 16.4 0.38 9.4 4.1 2.0 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4407 PF14362.1 EIW69207.1 - 0.56 9.1 9.0 0.029 13.3 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_S46 PF10459.4 EIW69207.1 - 0.58 8.5 6.2 0.64 8.3 4.3 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF342 PF03961.8 EIW69207.1 - 0.71 8.2 8.3 1.1 7.6 5.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Hemagglutinin PF00509.13 EIW69207.1 - 0.73 7.8 3.9 0.19 9.7 0.5 1.5 2 0 0 2 2 2 0 Haemagglutinin HrpB7 PF09486.5 EIW69207.1 - 0.76 9.6 7.9 0.18 11.7 0.9 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Fib_alpha PF08702.5 EIW69207.1 - 0.84 9.7 10.2 1.5 8.8 1.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cauli_AT PF03233.8 EIW69207.1 - 0.99 9.0 8.8 0.64 9.7 1.7 2.0 1 1 1 2 2 2 0 Aphid transmission protein YgaB PF14182.1 EIW69207.1 - 1.2 9.4 13.7 0.07 13.3 3.1 2.7 2 1 0 2 2 2 0 YgaB-like protein NEP PF10167.4 EIW69207.1 - 1.4 8.6 6.6 0.79 9.4 0.4 2.3 2 1 0 2 2 2 0 Uncharacterised conserved protein ATP-synt_B PF00430.13 EIW69207.1 - 1.5 8.6 16.2 0.94 9.2 3.3 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) COG5 PF10392.4 EIW69207.1 - 1.6 8.7 8.1 0.42 10.5 1.2 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Sec2p PF06428.6 EIW69207.1 - 2 8.2 14.9 3.9 7.3 4.9 2.5 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p TBPIP PF07106.8 EIW69207.1 - 2.2 7.8 14.3 0.73 9.3 3.2 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cluap1 PF10234.4 EIW69207.1 - 2.3 7.3 14.1 1.2 8.2 3.0 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 Spc7 PF08317.6 EIW69207.1 - 2.4 6.7 15.3 4.1 5.9 10.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 EIW69207.1 - 2.5 7.9 16.2 0.84 9.4 3.6 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1090 PF06476.7 EIW69207.1 - 2.6 7.7 12.8 0.31 10.7 4.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1090) Mto2_bdg PF12808.2 EIW69207.1 - 2.7 8.1 9.2 0.83 9.8 0.5 2.7 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FliJ PF02050.11 EIW69207.1 - 2.7 8.0 20.9 2.1 8.3 6.2 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein TcdA_TcdB PF12919.2 EIW69207.1 - 2.8 6.3 6.5 3.3 6.0 4.5 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF641 PF04859.7 EIW69207.1 - 2.8 7.6 12.1 0.36 10.5 3.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) BRE1 PF08647.6 EIW69207.1 - 2.9 7.9 11.6 0.75 9.8 2.3 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase WXG100 PF06013.7 EIW69207.1 - 3.3 7.7 9.2 10 6.1 0.8 2.7 2 1 0 2 2 2 0 Proteins of 100 residues with WXG AAA_13 PF13166.1 EIW69207.1 - 3.3 6.0 13.8 12 4.2 9.5 1.7 1 1 0 1 1 1 0 AAA domain Sec8_exocyst PF04048.9 EIW69207.1 - 3.5 7.2 8.7 3.3 7.3 0.9 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF4201 PF13870.1 EIW69207.1 - 3.6 6.9 14.1 5.1 6.5 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) PTS_IIA PF02255.11 EIW69207.1 - 4.2 7.3 6.9 11 5.9 0.4 2.2 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit MalF_P2 PF14785.1 EIW69207.1 - 4.2 7.2 9.1 3 7.6 1.6 2.1 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain TPR_MLP1_2 PF07926.7 EIW69207.1 - 4.3 7.0 13.6 3 7.5 2.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.3 EIW69207.1 - 4.7 6.9 13.9 2.3 7.9 2.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FliD_N PF02465.13 EIW69207.1 - 5.2 7.4 12.4 3 8.2 1.4 2.2 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Adeno_PIX PF03955.9 EIW69207.1 - 6.7 7.2 7.1 1.9 9.0 0.6 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) DMPK_coil PF08826.5 EIW69207.1 - 8 6.4 20.1 9.3 6.2 5.6 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF3552 PF12072.3 EIW69207.1 - 8.2 5.5 17.0 1.1 8.4 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Kinesin-relat_1 PF12711.2 EIW69207.1 - 8.4 6.8 11.5 2.5 8.5 1.3 2.4 2 1 0 2 2 2 0 Kinesin motor Snf7 PF03357.16 EIW69207.1 - 8.8 5.6 13.7 0.4 10.0 3.7 2.3 2 1 1 3 3 3 0 Snf7 Med4 PF10018.4 EIW69207.1 - 9.2 5.6 11.5 0.76 9.1 2.5 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 CCDC-167 PF15188.1 EIW69207.1 - 9.7 6.2 12.4 6.5 6.7 1.4 2.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Thioredoxin PF00085.15 EIW69209.1 - 4.7e-46 154.7 0.0 2.9e-26 91.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EIW69209.1 - 1.8e-21 76.8 0.0 9.6e-09 35.2 0.0 3.7 1 1 2 4 4 4 4 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIW69209.1 - 6.5e-11 42.2 0.0 2.1e-05 24.5 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EIW69209.1 - 3.6e-09 36.7 1.3 1.3e-06 28.5 0.0 3.8 3 2 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EIW69209.1 - 2.8e-05 24.0 0.1 0.00093 19.1 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.1 EIW69209.1 - 3.1e-05 24.0 0.2 0.67 9.9 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin AhpC-TSA PF00578.16 EIW69209.1 - 7.5e-05 22.4 0.1 0.023 14.3 0.0 3.4 3 1 1 4 4 4 1 AhpC/TSA family Thioredoxin_3 PF13192.1 EIW69209.1 - 0.0072 16.1 0.0 0.3 10.9 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain TraF PF13728.1 EIW69209.1 - 0.015 14.7 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 F plasmid transfer operon protein DUF2530 PF10745.4 EIW69209.1 - 0.016 15.1 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Thioredoxin_9 PF14595.1 EIW69209.1 - 0.016 14.7 0.0 0.46 10.0 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin DDE_Tnp_1_2 PF13586.1 EIW69209.1 - 0.032 14.4 0.2 5.4 7.2 0.0 3.6 3 1 1 4 4 4 0 Transposase DDE domain Calsequestrin PF01216.12 EIW69209.1 - 0.091 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Calsequestrin UPF0506 PF11703.3 EIW69209.1 - 0.18 11.7 1.0 9.7 6.2 0.1 2.5 2 0 0 2 2 2 0 UPF0506 Snf7 PF03357.16 EIW69210.1 - 8.6e-38 129.3 23.5 8.6e-38 129.3 16.3 1.4 2 0 0 2 2 2 1 Snf7 Peptidase_S46 PF10459.4 EIW69210.1 - 0.032 12.6 7.3 0.04 12.3 5.1 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF2890 PF11081.3 EIW69210.1 - 0.25 11.3 6.7 0.062 13.3 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Ist1 PF03398.9 EIW69210.1 - 0.31 10.4 4.9 0.45 9.9 3.4 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.3 EIW69210.1 - 1.7 8.6 17.7 1.3 9.0 5.1 2.2 1 1 1 2 2 2 0 YlqD protein TPR_MLP1_2 PF07926.7 EIW69210.1 - 2.1 8.0 14.5 6.4 6.5 10.0 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.7 EIW69210.1 - 2.7 7.2 21.4 0.049 12.9 6.9 2.1 1 1 0 2 2 2 0 PspA/IM30 family DUF677 PF05055.7 EIW69210.1 - 3.2 6.3 10.9 0.59 8.7 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF677) Fungal_trans PF04082.13 EIW69211.1 - 2.8e-17 62.4 0.2 4.4e-17 61.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2099 PF09872.4 EIW69215.1 - 0.017 14.1 0.7 0.028 13.4 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) BTB PF00651.26 EIW69218.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 EIW69218.1 - 0.013 15.6 1.4 0.025 14.6 0.2 2.1 3 0 0 3 3 3 0 Skp1 family, tetramerisation domain DUF3716 PF12511.3 EIW69219.1 - 0.73 9.4 5.8 1.3 8.7 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Hexokinase_2 PF03727.11 EIW69221.1 - 8.5e-81 270.7 0.0 1.2e-80 270.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIW69221.1 - 3.9e-65 219.0 0.0 7.3e-65 218.1 0.0 1.4 2 0 0 2 2 2 1 Hexokinase Bac_DNA_binding PF00216.16 EIW69221.1 - 0.058 13.4 0.0 18 5.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial DNA-binding protein UBN2_2 PF14227.1 EIW69222.1 - 4.1e-08 32.7 0.1 1.3e-07 31.1 0.0 1.9 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW69222.1 - 5.1e-07 29.4 0.0 1.3e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW69222.1 - 6.7e-05 22.4 3.3 0.14 11.7 0.4 3.4 3 0 0 3 3 3 3 gag-polypeptide of LTR copia-type Trypan_PARP PF05887.6 EIW69222.1 - 0.98 9.2 3.6 1.9 8.3 2.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Proteasome PF00227.21 EIW69223.1 - 2.2e-56 190.1 0.1 2.9e-56 189.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW69223.1 - 3.4e-15 55.0 0.0 6.5e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3289 PF11692.3 EIW69223.1 - 0.098 11.9 0.2 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) zf-rbx1 PF12678.2 EIW69227.1 - 6.4e-15 55.0 0.9 1.1e-14 54.3 0.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EIW69227.1 - 1.8e-13 50.0 4.1 3.4e-13 49.1 2.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIW69227.1 - 1.1e-07 31.3 3.3 1.9e-07 30.6 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW69227.1 - 5e-06 26.1 3.5 1e-05 25.1 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW69227.1 - 6.2e-06 26.1 5.2 2.8e-05 24.0 3.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW69227.1 - 9.4e-06 25.3 0.5 2e-05 24.3 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EIW69227.1 - 2.9e-05 23.6 2.3 8.5e-05 22.1 1.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EIW69227.1 - 3.9e-05 23.2 6.8 0.00021 20.8 4.7 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW69227.1 - 0.0019 18.0 1.7 0.0043 16.9 1.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EIW69227.1 - 0.017 15.0 1.2 0.033 14.1 0.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain NRPS PF08415.5 EIW69227.1 - 0.55 10.0 3.8 16 5.3 0.1 3.5 3 0 0 3 3 3 0 Nonribosomal peptide synthase zf-RING_4 PF14570.1 EIW69227.1 - 1.7 8.3 4.6 0.68 9.5 1.2 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ABC_tran PF00005.22 EIW69228.1 - 2.8e-51 173.4 0.0 3.5e-24 85.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EIW69228.1 - 1.2e-25 89.9 31.5 1.7e-13 50.2 9.6 3.3 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.1 EIW69228.1 - 2.7e-18 66.9 0.3 0.0001 22.3 0.0 4.5 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EIW69228.1 - 3.1e-09 36.2 0.9 0.0024 17.3 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EIW69228.1 - 5.2e-09 35.7 1.3 0.0033 16.8 0.3 2.7 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EIW69228.1 - 1.1e-08 35.9 0.0 0.0071 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIW69228.1 - 4.7e-08 33.2 0.5 0.0015 18.5 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EIW69228.1 - 7.5e-08 31.7 0.1 0.0022 17.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIW69228.1 - 1.9e-07 31.2 0.0 0.037 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIW69228.1 - 4e-07 29.4 0.2 0.026 13.7 0.0 4.0 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EIW69228.1 - 6.6e-07 29.4 0.0 0.016 15.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EIW69228.1 - 6.6e-07 29.8 0.0 0.035 14.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EIW69228.1 - 6.9e-07 28.9 0.5 0.013 14.9 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_19 PF13245.1 EIW69228.1 - 2e-06 27.4 0.3 0.00056 19.5 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 EIW69228.1 - 3.5e-06 26.5 0.0 0.012 15.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EIW69228.1 - 9.8e-06 25.8 0.0 0.24 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EIW69228.1 - 1.3e-05 24.7 0.4 0.0034 16.8 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 EIW69228.1 - 2.1e-05 24.2 0.0 0.057 13.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 EIW69228.1 - 8.5e-05 22.4 0.0 0.67 9.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EIW69228.1 - 9.2e-05 22.2 0.0 0.061 13.0 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 EIW69228.1 - 0.00051 19.9 0.0 1.3 8.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EIW69228.1 - 0.00068 20.1 0.0 2 8.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 EIW69228.1 - 0.0013 18.3 0.7 0.37 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EIW69228.1 - 0.0018 17.4 0.0 3.9 6.4 0.0 3.9 4 0 0 4 4 4 0 AAA ATPase domain AAA_14 PF13173.1 EIW69228.1 - 0.0019 18.0 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EIW69228.1 - 0.002 18.0 2.6 0.58 9.9 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 MobB PF03205.9 EIW69228.1 - 0.0037 16.9 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EIW69228.1 - 0.0041 16.5 0.8 0.7 9.3 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EIW69228.1 - 0.0064 16.0 0.2 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EIW69228.1 - 0.0089 15.7 0.3 3.6 7.2 0.0 3.3 3 0 0 3 3 3 0 NTPase RNA_helicase PF00910.17 EIW69228.1 - 0.012 15.8 0.0 7.9 6.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase T2SE PF00437.15 EIW69228.1 - 0.014 14.3 0.1 0.1 11.4 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 EIW69228.1 - 0.016 14.7 0.4 3 7.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EIW69228.1 - 0.018 14.9 0.2 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_5 PF07728.9 EIW69228.1 - 0.021 14.5 0.3 7.2 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EIW69228.1 - 0.024 14.2 0.3 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EIW69228.1 - 0.029 13.2 0.0 0.42 9.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 EIW69228.1 - 0.03 14.5 0.1 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 EIW69228.1 - 0.045 12.3 0.6 0.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.20 EIW69228.1 - 0.11 12.0 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 EIW69228.1 - 0.11 11.9 0.1 7.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.13 EIW69228.1 - 0.11 11.9 0.3 6.7 6.2 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.7 EIW69228.1 - 0.13 11.5 1.2 0.52 9.5 0.2 2.3 3 0 0 3 3 2 0 Poxvirus A32 protein Viral_helicase1 PF01443.13 EIW69228.1 - 0.19 11.2 0.0 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 EIW69228.1 - 0.68 8.9 1.4 14 4.6 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin ArgK PF03308.11 EIW69228.1 - 1.6 7.4 5.0 14 4.3 0.0 3.0 4 0 0 4 4 3 0 ArgK protein L51_S25_CI-B8 PF05047.11 EIW69231.1 - 1.2e-07 31.3 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF3505 PF12013.3 EIW69235.1 - 2.1e-10 40.8 2.8 2.1e-10 40.8 1.9 3.1 2 1 0 3 3 3 1 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 EIW69235.1 - 1.3 9.1 11.2 0.44 10.6 0.4 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Fer4_10 PF13237.1 EIW69235.1 - 6.1 6.7 8.2 4.1 7.2 0.6 3.1 3 1 0 3 3 3 0 4Fe-4S dicluster domain CMV_1a PF12467.3 EIW69236.1 - 0.095 13.0 3.8 0.11 12.8 2.6 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family bact-PGI_C PF10432.4 EIW69236.1 - 0.1 12.3 0.6 0.15 11.7 0.4 1.2 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region ROKNT PF08067.6 EIW69236.1 - 0.13 12.1 0.3 0.13 12.1 0.2 1.9 2 0 0 2 2 2 0 ROKNT (NUC014) domain DUF4407 PF14362.1 EIW69236.1 - 3.1 6.6 6.0 3.6 6.4 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3807 PF12720.2 EIW69236.1 - 3.3 7.8 11.4 4.1 7.5 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF3760 PF12586.3 EIW69238.1 - 0.015 15.1 0.1 63 3.5 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF3760) FAM165 PF14981.1 EIW69238.1 - 0.046 13.2 0.0 66 3.1 0.0 3.4 3 0 0 3 3 3 0 FAM165 family SNF2_assoc PF08455.5 EIW69238.1 - 0.079 11.5 0.0 8.1 4.9 0.0 3.4 2 2 1 3 3 3 0 Bacterial SNF2 helicase associated Nyv1_N PF09426.5 EIW69238.1 - 0.18 11.3 0.1 19 4.7 0.0 2.8 3 0 0 3 3 3 0 Vacuolar R-SNARE Nyv1 N terminal Polysacc_lyase PF14099.1 EIW69238.1 - 0.21 11.2 0.2 12 5.4 0.1 2.3 2 0 0 2 2 2 0 Polysaccharide lyase Calsequestrin PF01216.12 EIW69238.1 - 0.24 10.1 0.0 3.2 6.4 0.0 2.8 3 0 0 3 3 3 0 Calsequestrin rve PF00665.21 EIW69241.1 - 0.027 14.5 0.0 0.1 12.7 0.0 1.9 1 1 1 2 2 2 0 Integrase core domain Transaldolase PF00923.14 EIW69242.1 - 3.2e-17 62.5 0.0 4.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Transaldolase MR_MLE_C PF13378.1 EIW69243.1 - 3.2e-15 56.0 0.0 7.3e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EIW69243.1 - 3.4e-11 43.4 0.3 9.3e-11 42.1 0.1 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EIW69243.1 - 9.4e-05 22.3 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EIW69243.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DUF3437 PF11919.3 EIW69243.1 - 0.035 13.8 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Zn_Tnp_IS1 PF03811.8 EIW69247.1 - 0.11 12.0 0.5 1.4 8.5 0.3 2.3 2 0 0 2 2 2 0 InsA N-terminal domain DUF4376 PF14301.1 EIW69248.1 - 0.075 13.1 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) EthD PF07110.6 EIW69248.1 - 0.085 13.8 1.2 1.8 9.5 0.0 2.7 2 1 0 2 2 2 0 EthD domain DUF2823 PF11034.3 EIW69248.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2823) DUF2587 PF10759.4 EIW69252.1 - 0.038 13.3 0.1 0.12 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) CDK2AP PF09806.4 EIW69252.1 - 9.6 6.3 16.9 0.18 12.0 6.4 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein zf-CCHC PF00098.18 EIW69253.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW69253.1 - 0.27 11.5 9.2 0.069 13.3 4.2 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW69253.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Fcf1 PF04900.7 EIW69255.1 - 1.9e-21 76.0 0.0 2.7e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Fcf1 SUZ PF12752.2 EIW69256.1 - 1.1e-09 38.6 0.9 1.1e-09 38.6 0.6 3.2 4 0 0 4 4 4 1 SUZ domain DBR1 PF05011.8 EIW69256.1 - 2.8 7.8 5.3 1.3 8.8 1.9 1.8 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain Cytochrom_D1 PF02239.11 EIW69257.1 - 0.1 10.8 0.0 0.39 8.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40 PF00400.27 EIW69257.1 - 1.1 9.3 24.9 0.4 10.6 0.0 7.8 9 1 0 9 9 9 0 WD domain, G-beta repeat Tfb4 PF03850.9 EIW69258.1 - 1.2e-37 129.6 0.0 2.2e-37 128.8 0.0 1.4 1 1 0 1 1 1 1 Transcription factor Tfb4 GTP_CH_N PF12471.3 EIW69259.1 - 1.9e-46 158.1 0.2 2e-38 131.9 0.0 2.4 1 1 1 2 2 2 2 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EIW69259.1 - 4.2e-16 58.6 0.0 6.7e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II UBN2_3 PF14244.1 EIW69262.1 - 1.1e-05 25.0 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIW69262.1 - 0.00011 21.6 0.0 0.00024 20.6 0.0 1.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW69262.1 - 0.00066 19.4 0.0 0.0019 17.9 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type JAB PF01398.16 EIW69263.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SH3_9 PF14604.1 EIW69264.1 - 1.7e-05 24.3 0.1 3.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW69264.1 - 0.0075 15.6 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Daxx PF03344.10 EIW69266.1 - 0.00049 18.7 2.7 0.00049 18.7 1.9 1.8 2 0 0 2 2 2 1 Daxx Family Nop14 PF04147.7 EIW69266.1 - 2.3 6.0 16.3 3.5 5.4 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EIW69266.1 - 3.1 6.9 16.2 6.6 5.9 11.2 1.4 1 0 0 1 1 1 0 SDA1 GHMP_kinases_N PF00288.21 EIW69267.1 - 1.8e-11 43.8 1.2 3.8e-11 42.8 0.8 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIW69267.1 - 2.6e-11 43.5 0.0 6.9e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_Tnp_Tc3_2 PF01498.13 EIW69269.1 - 0.0014 18.6 1.6 0.0014 18.6 1.1 1.7 2 0 0 2 2 2 1 Transposase gag_pre-integrs PF13976.1 EIW69272.1 - 6.1e-09 35.4 0.6 9.5e-09 34.7 0.1 1.5 2 0 0 2 2 2 1 GAG-pre-integrase domain FA_desaturase PF00487.19 EIW69274.1 - 1.7e-13 50.6 21.4 1.7e-13 50.6 14.8 1.8 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIW69274.1 - 1.1e-06 28.2 0.0 0.004 16.9 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Dendrin PF15498.1 EIW69274.1 - 0.023 13.2 0.2 0.035 12.6 0.2 1.2 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin PolC_DP2 PF03833.8 EIW69275.1 - 0.0095 13.6 0.3 0.011 13.4 0.2 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 DUF1394 PF07159.7 EIW69277.1 - 0.0033 16.5 0.0 0.0046 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Helitron_like_N PF14214.1 EIW69277.1 - 0.031 14.0 0.5 0.052 13.2 0.3 1.4 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus DUF3825 PF12873.2 EIW69278.1 - 0.13 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) DUF4462 PF14692.1 EIW69279.1 - 0.021 14.0 3.8 6.1 6.1 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4462) GLYCAM-1 PF05242.6 EIW69280.1 - 0.045 13.6 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Pterin_bind PF00809.17 EIW69282.1 - 2.6e-51 174.0 0.0 3.9e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EIW69282.1 - 3e-36 123.9 0.0 5.2e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EIW69282.1 - 2e-14 53.6 0.0 5e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 Dihydroneopterin aldolase Aconitase PF00330.15 EIW69283.1 - 2.1e-159 530.9 0.0 2.5e-158 527.4 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIW69283.1 - 4.2e-37 127.1 0.0 7.5e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 EIW69283.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) DUF469 PF04320.9 EIW69283.1 - 0.23 12.2 0.0 0.55 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein with unknown function (DUF469) Pkinase PF00069.20 EIW69284.1 - 2.8e-61 206.9 0.0 2.9e-40 138.0 0.0 4.5 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69284.1 - 1.2e-32 113.0 0.0 1.1e-20 73.7 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 EIW69284.1 - 8.1e-20 71.0 0.0 8.1e-20 71.0 0.0 3.3 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs RWD PF05773.17 EIW69284.1 - 4.8e-14 52.2 0.0 1.5e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EIW69284.1 - 2.7e-10 39.8 1.1 4.9e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kdo PF06293.9 EIW69284.1 - 7.1e-05 21.9 0.0 0.066 12.2 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW69284.1 - 7.5e-05 22.5 0.0 0.00026 20.8 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family CENP-B_dimeris PF09026.5 EIW69284.1 - 0.0019 18.3 1.7 0.0055 16.9 1.2 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain RIO1 PF01163.17 EIW69284.1 - 0.0082 15.5 0.1 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EIW69284.1 - 0.01 14.8 0.0 0.18 10.7 0.0 2.7 3 0 0 3 3 3 0 Kinase-like PC_rep PF01851.17 EIW69285.1 - 1.3e-36 122.7 14.5 2e-06 27.7 0.0 9.5 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EIW69285.1 - 7e-16 58.2 3.1 1.4e-10 41.2 0.0 4.5 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EIW69285.1 - 3.3e-07 29.8 7.2 0.13 12.3 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EIW69285.1 - 2.9e-05 24.4 7.9 0.19 12.2 0.1 5.0 3 1 2 5 5 5 3 HEAT-like repeat Arm PF00514.18 EIW69285.1 - 0.053 13.3 1.0 26 4.8 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HTH_Tnp_Tc5 PF03221.11 EIW69288.1 - 1.1e-05 25.1 0.0 2.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EIW69288.1 - 0.00041 19.8 0.1 0.0013 18.2 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_10 PF04967.7 EIW69288.1 - 0.041 13.4 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain DDE_1 PF03184.14 EIW69290.1 - 3e-27 95.1 0.0 4.4e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4339 PF14237.1 EIW69290.1 - 0.5 9.9 3.1 0.52 9.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4339) Asparaginase PF00710.15 EIW69292.1 - 1.6e-82 276.8 0.0 1.9e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 Asparaginase RhoGEF PF00621.15 EIW69293.1 - 4.7e-27 95.0 0.0 3.2e-23 82.5 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain RNA_pol_Rpb4 PF03874.11 EIW69294.1 - 5.6e-13 48.9 0.0 7.4e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Suc_Fer-like PF06999.7 EIW69295.1 - 3.1e-23 82.9 1.8 1.2e-22 81.0 0.0 2.2 1 1 1 2 2 2 1 Sucrase/ferredoxin-like Fer2 PF00111.22 EIW69295.1 - 4.4e-07 29.5 0.2 9.5e-07 28.4 0.0 1.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain SR-25 PF10500.4 EIW69295.1 - 0.0034 16.8 9.1 0.0034 16.8 6.3 2.9 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF155 PF02582.9 EIW69296.1 - 6.1e-51 172.7 1.0 8.3e-51 172.3 0.7 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 MCM PF00493.18 EIW69298.1 - 1e-135 451.8 0.0 1.4e-135 451.4 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIW69298.1 - 9.6e-23 80.9 0.1 6e-22 78.4 0.0 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIW69298.1 - 4.9e-08 32.3 0.0 8.5e-05 21.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIW69298.1 - 9.4e-08 31.8 0.0 3.3e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIW69298.1 - 0.00015 21.3 0.0 0.0018 17.8 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW69298.1 - 0.0012 18.3 0.1 1.3 8.5 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain Aminotran_1_2 PF00155.16 EIW69299.1 - 3.9e-81 272.8 0.0 4.5e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RNA_polI_A14 PF08203.6 EIW69299.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Pkinase PF00069.20 EIW69300.1 - 9.3e-54 182.2 0.0 2.7e-52 177.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69300.1 - 5.2e-23 81.4 0.0 2.5e-22 79.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EIW69300.1 - 0.13 12.0 0.3 0.28 10.8 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family ADH_N PF08240.7 EIW69301.1 - 2.9e-28 97.7 0.9 2.9e-28 97.7 0.6 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW69301.1 - 4.7e-12 45.5 0.0 3.6e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIW69301.1 - 0.033 13.3 0.0 0.081 12.0 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EIW69301.1 - 0.079 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Arf PF00025.16 EIW69302.1 - 4.1e-69 231.3 0.1 4.7e-69 231.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EIW69302.1 - 1.3e-11 43.8 1.3 3.3e-06 26.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EIW69302.1 - 8.9e-10 38.0 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EIW69302.1 - 1.3e-08 34.4 0.0 1.5e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EIW69302.1 - 6.3e-08 32.0 0.0 7.6e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIW69302.1 - 4.8e-07 29.7 0.0 7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW69302.1 - 6.4e-07 29.8 0.0 8.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EIW69302.1 - 3.3e-05 23.4 0.0 0.0012 18.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EIW69302.1 - 0.043 14.6 0.0 0.058 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW69302.1 - 0.095 13.0 0.0 0.15 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EIW69302.1 - 0.11 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SR-25 PF10500.4 EIW69304.1 - 0.41 10.0 29.7 0.11 11.9 9.4 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.18 EIW69305.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW69305.1 - 0.27 11.5 9.2 0.069 13.3 4.2 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW69305.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) HTH_Tnp_Tc3_2 PF01498.13 EIW69307.1 - 1.1e-13 50.9 2.5 4.5e-13 49.0 0.3 2.2 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIW69307.1 - 1.2e-06 28.6 0.2 2.2e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EIW69307.1 - 3.8e-05 23.5 2.9 0.00044 20.1 0.0 2.9 3 1 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.1 EIW69307.1 - 4.8e-05 22.8 2.6 0.00068 19.2 0.0 3.2 4 0 0 4 4 3 1 Homeodomain-like domain HTH_32 PF13565.1 EIW69307.1 - 0.00024 21.8 1.0 0.00045 20.9 0.1 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIW69307.1 - 0.0078 15.3 1.1 0.015 14.4 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.7 EIW69307.1 - 0.02 14.3 0.1 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 DUF2083 PF09856.4 EIW69307.1 - 0.045 13.3 0.1 0.075 12.6 0.1 1.3 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) HTH_24 PF13412.1 EIW69307.1 - 0.051 12.9 0.4 0.71 9.3 0.1 2.6 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_4 PF13613.1 EIW69307.1 - 0.074 12.5 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Sigma54_DBD PF04552.8 EIW69307.1 - 0.35 10.3 1.9 17 4.8 0.1 2.4 2 1 0 2 2 2 0 Sigma-54, DNA binding domain Resolvase PF00239.16 EIW69308.1 - 0.0032 17.3 2.8 0.0051 16.6 1.9 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain B56 PF01603.15 EIW69308.1 - 0.26 9.8 2.4 0.34 9.4 1.7 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) PfkB PF00294.19 EIW69310.1 - 1.4e-08 34.2 0.0 2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Transp_cyt_pur PF02133.10 EIW69311.1 - 6.9e-94 314.8 27.2 8.6e-94 314.5 18.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pex14_N PF04695.8 EIW69314.1 - 1.8e-25 89.5 0.9 4.8e-23 81.7 0.0 2.8 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 EIW69314.1 - 0.0019 17.8 2.7 0.0042 16.7 2.0 1.4 1 1 0 1 1 1 1 IncA protein DUF1664 PF07889.7 EIW69314.1 - 0.0064 16.2 0.8 0.013 15.2 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) EzrA PF06160.7 EIW69314.1 - 0.0075 14.4 0.2 0.0097 14.1 0.1 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4235 PF14019.1 EIW69314.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) Spectrin PF00435.16 EIW69314.1 - 0.024 14.9 1.4 0.067 13.4 0.8 1.7 1 1 1 2 2 2 0 Spectrin repeat Laminin_II PF06009.7 EIW69314.1 - 0.025 14.3 2.1 0.11 12.2 0.2 2.0 1 1 1 2 2 2 0 Laminin Domain II CHASE3 PF05227.8 EIW69314.1 - 0.026 14.2 4.7 0.064 12.9 1.2 2.1 1 1 1 2 2 2 0 CHASE3 domain WEMBL PF05701.6 EIW69314.1 - 0.028 12.8 1.0 0.035 12.5 0.7 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light SF-assemblin PF06705.6 EIW69314.1 - 0.038 13.1 2.0 0.22 10.6 0.8 1.8 1 1 1 2 2 2 0 SF-assemblin/beta giardin MscS_porin PF12795.2 EIW69314.1 - 0.059 12.6 5.4 0.47 9.7 1.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Syntaxin PF00804.20 EIW69314.1 - 0.082 13.0 2.3 4.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Syntaxin DUF3584 PF12128.3 EIW69314.1 - 0.083 10.2 2.1 0.11 9.8 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 EIW69314.1 - 0.087 12.2 2.3 0.2 11.0 1.5 1.6 1 1 0 1 1 1 0 Intermediate filament protein Spc24 PF08286.6 EIW69314.1 - 0.15 11.7 1.8 9.8 5.8 0.2 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.7 EIW69314.1 - 0.16 12.2 0.9 4.2 7.6 0.0 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein AATF-Che1 PF13339.1 EIW69314.1 - 0.17 11.9 4.6 0.064 13.4 0.5 1.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor ALIX_LYPXL_bnd PF13949.1 EIW69314.1 - 0.22 10.4 6.6 1.1 8.1 4.5 1.8 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV Spc7 PF08317.6 EIW69314.1 - 0.44 9.1 2.7 1 7.9 0.3 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.6 EIW69314.1 - 1.3 8.9 6.0 6.5 6.6 1.1 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 EIW69314.1 - 1.3 8.7 4.3 53 3.5 3.0 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HalX PF08663.5 EIW69314.1 - 3.1 7.8 7.1 4.4 7.3 0.4 2.8 3 0 0 3 3 3 0 HalX domain PCNA_N PF00705.13 EIW69315.1 - 5.8e-53 177.7 4.3 8e-53 177.3 2.3 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EIW69315.1 - 2.7e-43 146.9 0.6 9.5e-23 80.5 0.0 2.7 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EIW69315.1 - 1.9e-06 27.2 0.0 5.2e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Rad9 Rad1 PF02144.11 EIW69315.1 - 1.7e-05 23.7 5.8 0.0012 17.6 4.0 2.5 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 YL1 PF05764.8 EIW69315.1 - 0.0032 17.1 5.8 0.0038 16.8 4.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Trypan_PARP PF05887.6 EIW69315.1 - 0.0033 17.2 8.9 0.0053 16.5 6.1 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 EIW69315.1 - 0.015 13.8 10.2 0.019 13.4 7.1 1.1 1 0 0 1 1 1 0 Daxx Family Hus1 PF04005.7 EIW69315.1 - 0.015 14.2 2.9 1.5 7.6 0.0 3.3 3 1 1 4 4 4 0 Hus1-like protein Nop14 PF04147.7 EIW69315.1 - 0.033 12.1 11.7 0.038 11.9 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family TLP-20 PF06088.6 EIW69315.1 - 0.05 13.2 1.2 0.073 12.7 0.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NOA36 PF06524.7 EIW69315.1 - 0.062 12.5 7.3 0.1 11.8 5.1 1.3 1 0 0 1 1 1 0 NOA36 protein RR_TM4-6 PF06459.7 EIW69315.1 - 0.11 12.4 5.3 0.14 12.0 3.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 EIW69315.1 - 0.12 10.4 4.9 0.14 10.1 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EIW69315.1 - 0.65 9.5 10.0 1.2 8.6 7.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin eIF-3c_N PF05470.7 EIW69315.1 - 1.8 6.5 7.5 2.7 5.9 5.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3381 PF11861.3 EIW69315.1 - 2.7 7.4 10.5 40 3.6 7.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) U79_P34 PF03064.11 EIW69315.1 - 3 7.2 12.0 4.7 6.6 8.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PBP1_TM PF14812.1 EIW69315.1 - 8.8 6.7 12.6 18 5.7 8.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Syja_N PF02383.13 EIW69316.1 - 6e-66 222.3 0.0 7.7e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain LCCL PF03815.14 EIW69317.1 - 2e-05 24.4 0.0 3.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 LCCL domain CAP59_mtransfer PF11735.3 EIW69318.1 - 1.8e-51 174.7 0.0 2.4e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Spc7 PF08317.6 EIW69319.1 - 7.3e-44 149.7 0.5 1.3e-43 148.8 0.2 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EIW69319.1 - 5.6e-12 45.1 0.4 2e-11 43.3 0.3 2.0 1 0 0 1 1 1 1 Spc7_C2 CotE PF10628.4 EIW69319.1 - 0.0073 15.7 0.3 0.014 14.7 0.2 1.4 1 0 0 1 1 1 1 Outer spore coat protein E (CotE) IncA PF04156.9 EIW69319.1 - 0.04 13.5 5.9 1.1 8.8 0.2 3.1 2 1 1 3 3 3 0 IncA protein 5HT_transporter PF03491.8 EIW69319.1 - 0.62 10.2 3.4 5.5 7.1 0.1 3.3 3 0 0 3 3 3 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus NAD_binding_1 PF00175.16 EIW69320.1 - 4.3e-30 104.5 0.0 6.1e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIW69320.1 - 2.9e-29 101.0 0.0 4.6e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EIW69320.1 - 7.9e-06 25.8 0.0 7.6e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EIW69320.1 - 6.5e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain tRNA_anti-codon PF01336.20 EIW69320.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Aldedh PF00171.17 EIW69322.1 - 1e-69 235.0 0.0 1.3e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tetraspannin PF00335.15 EIW69322.1 - 0.34 10.1 1.9 0.55 9.4 1.3 1.3 1 0 0 1 1 1 0 Tetraspanin family Duffy_binding PF05424.6 EIW69323.1 - 0.11 12.3 0.3 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 Duffy binding domain DOT1 PF08123.8 EIW69323.1 - 0.12 11.7 0.2 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Cyclin_N PF00134.18 EIW69324.1 - 2.9e-35 120.6 0.2 5.5e-35 119.7 0.1 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIW69324.1 - 0.0005 19.9 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Aminotran_1_2 PF00155.16 EIW69325.1 - 2.9e-92 309.4 0.0 3.3e-92 309.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II GMC_oxred_N PF00732.14 EIW69326.1 - 3.9e-61 206.8 0.0 5.5e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW69326.1 - 6.5e-33 114.0 0.0 1.5e-32 112.8 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW69326.1 - 0.0014 17.5 0.4 0.006 15.5 0.1 2.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW69326.1 - 0.0016 18.5 0.1 0.84 9.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW69326.1 - 0.0026 17.7 0.1 0.0071 16.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIW69326.1 - 0.0045 15.9 0.4 0.009 14.9 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Leuk-A4-hydro_C PF09127.6 EIW69326.1 - 0.0091 15.6 0.3 0.83 9.2 0.1 2.4 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal PspC PF04024.7 EIW69326.1 - 0.011 15.1 0.4 0.033 13.6 0.3 1.8 1 0 0 1 1 1 0 PspC domain FAD_binding_2 PF00890.19 EIW69326.1 - 0.012 14.4 1.8 0.019 13.7 0.5 1.8 2 0 0 2 2 2 0 FAD binding domain RICTOR_M PF14666.1 EIW69328.1 - 1e-86 289.6 0.0 3.3e-84 281.4 0.0 3.4 2 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 EIW69328.1 - 6.8e-69 232.2 0.2 1.4e-68 231.2 0.1 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 EIW69328.1 - 1.1e-33 115.5 0.4 1.7e-32 111.7 0.1 2.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EIW69328.1 - 6.3e-25 86.9 0.1 4.3e-23 81.0 0.1 3.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 EIW69328.1 - 7.5e-07 29.3 4.6 0.95 9.7 0.0 5.7 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 EIW69328.1 - 0.044 13.8 0.1 89 3.5 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat CR6_interact PF10147.4 EIW69328.1 - 0.18 11.0 0.5 0.35 10.1 0.4 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Helicase_C PF00271.26 EIW69329.1 - 5.4e-20 71.0 0.1 1.5e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW69329.1 - 8.6e-19 67.6 0.0 3.8e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW69329.1 - 5e-18 65.5 0.3 5.2e-17 62.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Aminotran_5 PF00266.14 EIW69330.1 - 5.2e-26 91.2 0.0 7.3e-18 64.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V AIG2 PF06094.7 EIW69330.1 - 9.2e-08 32.5 0.0 3.1e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 AIG2-like family Aminotran_1_2 PF00155.16 EIW69330.1 - 4.3e-05 22.6 0.0 0.00018 20.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 EIW69330.1 - 0.029 12.8 0.1 0.074 11.4 0.1 1.6 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 EIW69330.1 - 0.086 11.8 0.0 11 4.9 0.0 2.8 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family ETC_C1_NDUFA4 PF04800.7 EIW69331.1 - 6.3e-36 122.2 0.6 1.1e-35 121.5 0.4 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region RNA_polI_A34 PF08208.6 EIW69335.1 - 0.00034 20.3 0.2 0.013 15.2 0.0 2.2 2 0 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 DUF4319 PF14203.1 EIW69335.1 - 0.067 12.7 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) LMBR1 PF04791.11 EIW69337.1 - 0.17 10.4 7.1 0.23 9.9 4.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GAS PF13851.1 EIW69337.1 - 0.8 8.8 20.2 1.2 8.3 14.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EIW69337.1 - 4 6.3 17.6 5.8 5.8 12.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PAS PF00989.19 EIW69338.1 - 0.00023 20.9 0.0 0.00071 19.3 0.0 1.9 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EIW69338.1 - 0.03 14.1 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain Pescadillo_N PF06732.6 EIW69339.1 - 4e-98 328.1 1.0 8.4e-98 327.0 0.0 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EIW69339.1 - 8.4e-06 25.8 0.0 2.2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Lactamase_B PF00753.22 EIW69340.1 - 9.9e-09 35.1 0.0 4.5e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW69340.1 - 8.9e-05 22.1 0.1 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain F_actin_cap_B PF01115.12 EIW69341.1 - 4e-62 209.5 0.0 4.6e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF1181 PF06680.6 EIW69341.1 - 0.14 11.7 0.1 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) CorA PF01544.13 EIW69342.1 - 2.9e-05 23.2 4.3 7.7e-05 21.8 3.1 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3549 PF12069.3 EIW69342.1 - 0.03 13.0 1.1 0.044 12.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) DUF1469 PF07332.6 EIW69342.1 - 0.05 13.3 0.3 0.093 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Daxx PF03344.10 EIW69344.1 - 3.3 6.0 8.1 4.3 5.7 5.6 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EIW69344.1 - 3.8 5.3 9.4 4.6 5.0 6.5 1.0 1 0 0 1 1 1 0 Nop14-like family DDE_1 PF03184.14 EIW69347.1 - 7.6e-17 61.1 0.0 8.6e-16 57.7 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW69347.1 - 0.0028 17.4 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DNA_pol_B PF00136.16 EIW69348.1 - 7.9e-91 305.1 0.0 1.1e-90 304.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EIW69348.1 - 2.1e-16 59.6 0.0 1.5e-11 43.7 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EIW69348.1 - 1.3e-11 44.2 4.5 2.4e-11 43.4 2.7 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 EIW69348.1 - 0.39 9.3 0.0 0.61 8.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Pyr_redox_2 PF07992.9 EIW69349.1 - 4.2e-12 46.3 0.0 0.0026 17.6 0.0 5.3 4 2 0 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW69349.1 - 1.4e-10 41.4 0.0 1.3e-08 35.0 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW69349.1 - 1.4e-06 27.4 0.3 0.016 14.1 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW69349.1 - 0.0021 18.1 0.1 0.23 11.4 0.1 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW69349.1 - 0.0023 17.9 0.0 1.9 8.5 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pribosyltran PF00156.22 EIW69349.1 - 0.025 14.2 0.0 0.26 11.0 0.0 2.4 3 0 0 3 3 3 0 Phosphoribosyl transferase domain Abhydrolase_5 PF12695.2 EIW69349.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Oxidored_q6 PF01058.17 EIW69349.1 - 0.12 12.0 0.0 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Lycopene_cycl PF05834.7 EIW69349.1 - 0.19 10.6 0.0 3.3 6.5 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein RCC1 PF00415.13 EIW69350.1 - 3.9e-20 71.7 4.3 2.6e-06 27.5 0.0 6.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIW69350.1 - 7.1e-18 63.7 13.9 6.7e-09 35.1 0.2 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EIW69350.1 - 1.8e-06 27.5 1.0 3.9e-06 26.4 0.7 1.6 1 0 0 1 1 1 1 F-box-like Adap_comp_sub PF00928.16 EIW69352.1 - 2.2e-52 177.7 0.0 3.2e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIW69352.1 - 2.1e-08 34.0 0.4 4.2e-08 33.0 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ras PF00071.17 EIW69353.1 - 2.2e-44 150.6 0.0 2.6e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW69353.1 - 7.8e-14 52.1 0.0 1.1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW69353.1 - 5.2e-09 35.5 0.0 5.8e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW69353.1 - 1.2e-07 31.3 0.1 2.8e-06 26.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW69353.1 - 0.00066 19.6 0.0 0.0013 18.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW69353.1 - 0.00074 18.8 0.1 0.034 13.4 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_28 PF13521.1 EIW69353.1 - 0.017 15.0 0.0 0.046 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 EIW69353.1 - 0.03 13.5 0.0 0.076 12.2 0.0 1.6 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EIW69353.1 - 0.059 13.2 0.0 0.078 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EIW69353.1 - 0.13 11.7 0.1 0.32 10.4 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation LMWPc PF01451.16 EIW69354.1 - 4.8e-24 85.2 0.0 5.3e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase HSP70 PF00012.15 EIW69356.1 - 2.6e-56 190.7 0.0 4.6e-56 189.9 0.0 1.4 1 0 0 1 1 1 1 Hsp70 protein PAPS_reduct PF01507.14 EIW69357.1 - 2.2e-38 131.8 0.0 2.6e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family BCIP PF13862.1 EIW69358.1 - 2.2e-36 125.1 0.0 2.8e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein 2OG-FeII_Oxy_2 PF13532.1 EIW69359.1 - 8.7e-32 110.5 0.1 1.9e-31 109.3 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Tim54 PF11711.3 EIW69359.1 - 0.081 11.5 1.9 0.11 11.0 1.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ORC6 PF05460.8 EIW69359.1 - 8.3 5.3 10.4 12 4.8 7.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pox_Ag35 PF03286.9 EIW69361.1 - 0.0046 16.5 0.3 0.0065 16.0 0.2 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein DUF1510 PF07423.6 EIW69361.1 - 0.0066 15.8 0.2 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EIW69361.1 - 0.013 13.2 0.2 0.015 13.0 0.2 1.1 1 0 0 1 1 1 0 Ycf1 BSP_II PF05432.6 EIW69361.1 - 0.1 11.8 15.5 0.051 12.8 8.3 2.2 1 1 1 2 2 2 0 Bone sialoprotein II (BSP-II) ATP-synt_8 PF00895.15 EIW69361.1 - 0.17 12.1 3.3 5 7.4 0.0 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 Nucleoplasmin PF03066.10 EIW69361.1 - 0.23 10.9 4.5 0.16 11.4 1.6 1.9 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 EIW69361.1 - 0.52 8.2 5.6 0.63 8.0 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 EIW69361.1 - 2.7 6.8 9.1 3.8 6.2 6.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 VID27 PF08553.5 EIW69361.1 - 3 5.9 7.8 4.1 5.5 5.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein YqfQ PF14181.1 EIW69361.1 - 3.1 7.8 5.3 6.7 6.7 3.7 1.5 1 0 0 1 1 1 0 YqfQ-like protein Paf1 PF03985.8 EIW69361.1 - 8.3 5.0 13.2 11 4.5 9.1 1.1 1 0 0 1 1 1 0 Paf1 Hep_59 PF07052.6 EIW69362.1 - 5.1e-25 87.8 6.3 5.1e-25 87.8 4.4 2.3 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Siah-Interact_N PF09032.6 EIW69362.1 - 0.19 11.8 5.2 0.082 12.9 0.8 2.5 2 0 0 2 2 2 0 Siah interacting protein, N terminal GPI-anchored PF10342.4 EIW69365.1 - 0.0012 19.3 2.7 0.0012 19.3 1.9 1.9 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Aa_trans PF01490.13 EIW69366.1 - 5.4e-43 147.0 13.5 5.8e-26 90.9 2.9 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DAO PF01266.19 EIW69367.1 - 4e-46 157.5 1.9 7.6e-46 156.6 1.3 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW69367.1 - 1e-06 27.8 1.3 2.6e-06 26.5 0.9 1.6 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EIW69367.1 - 2.5e-05 23.3 3.2 0.0015 17.4 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EIW69367.1 - 0.00029 20.7 0.7 0.0029 17.4 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW69367.1 - 0.024 13.7 0.8 0.066 12.2 0.6 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW69367.1 - 0.035 14.1 0.5 0.11 12.5 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIW69367.1 - 0.06 11.9 3.5 0.24 9.9 1.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EIW69367.1 - 0.1 12.3 0.4 8.4 6.1 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Strep_67kDa_ant PF06100.6 EIW69367.1 - 0.21 9.9 0.2 0.29 9.4 0.1 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family DUF241 PF03087.9 EIW69369.1 - 0.069 12.6 0.9 0.15 11.5 0.1 1.9 3 0 0 3 3 3 0 Arabidopsis protein of unknown function zf-CCHC PF00098.18 EIW69370.1 - 0.00022 20.9 1.3 0.00034 20.3 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW69370.1 - 0.051 13.2 0.5 0.19 11.4 0.4 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIW69370.1 - 0.13 12.0 1.3 0.25 11.1 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 EIW69370.1 - 1.6 8.6 7.2 6.3 6.7 4.9 2.0 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G UCH PF00443.24 EIW69374.1 - 1.3e-38 132.6 0.0 1.3e-37 129.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPEL PF02755.10 EIW69374.1 - 3.6e-11 42.0 0.0 2.2e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 RPEL repeat UCH_1 PF13423.1 EIW69374.1 - 1.8e-05 24.3 0.0 0.18 11.2 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase BAG PF02179.11 EIW69375.1 - 2.3e-10 40.4 0.0 5.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EIW69375.1 - 5e-08 32.2 0.0 1.1e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EIW69375.1 - 0.00066 19.3 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EIW69375.1 - 0.01 16.3 0.0 0.02 15.4 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Methyltransf_31 PF13847.1 EIW69376.1 - 2.7e-12 46.5 0.2 4.9e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIW69376.1 - 2.8e-10 39.7 0.0 4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EIW69376.1 - 4.2e-09 36.7 0.0 2.7e-08 34.1 0.0 2.2 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW69376.1 - 6.1e-09 36.4 0.1 2e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 EIW69376.1 - 8.3e-08 31.5 0.0 1.1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 EIW69376.1 - 3.2e-07 30.3 0.0 7e-07 29.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW69376.1 - 4.4e-07 29.7 0.0 8.8e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EIW69376.1 - 3.9e-06 25.7 0.0 5.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EIW69376.1 - 1.4e-05 24.5 0.1 2.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EIW69376.1 - 2e-05 24.8 0.0 4.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW69376.1 - 7.5e-05 23.1 0.0 0.00015 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIW69376.1 - 0.00014 21.9 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EIW69376.1 - 0.00059 18.9 0.0 0.00081 18.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EIW69376.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EIW69376.1 - 0.041 13.5 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EIW69376.1 - 0.041 13.3 0.1 0.062 12.7 0.1 1.2 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 EIW69376.1 - 0.046 13.2 0.1 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TehB PF03848.9 EIW69376.1 - 0.069 12.3 0.3 0.3 10.2 0.2 2.0 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 EIW69376.1 - 0.088 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Cofilin_ADF PF00241.15 EIW69377.1 - 7e-21 74.4 0.1 3.9e-11 42.9 0.0 3.2 2 1 1 3 3 3 2 Cofilin/tropomyosin-type actin-binding protein MIP-T3 PF10243.4 EIW69377.1 - 0.081 11.3 1.0 0.11 10.9 0.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UPF0029 PF01205.14 EIW69378.1 - 3.3e-12 46.0 0.0 5.9e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Ribosomal_L19e PF01280.15 EIW69378.1 - 0.0039 16.9 0.2 0.0085 15.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L19e PEP_mutase PF13714.1 EIW69378.1 - 0.083 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase UDPGT PF00201.13 EIW69380.1 - 3.7e-09 35.6 0.0 5.9e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Zn_clus PF00172.13 EIW69381.1 - 5.9e-05 22.8 13.4 9.8e-05 22.1 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSPc PF00782.15 EIW69382.1 - 1.1e-27 96.2 0.0 1.6e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EIW69382.1 - 0.017 15.4 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Rhodanese-like domain Y_phosphatase PF00102.22 EIW69382.1 - 0.027 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EIW69382.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family Mannosyl_trans PF05007.8 EIW69383.1 - 3.4e-54 184.2 17.7 1.7e-53 181.9 12.3 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) KRAB PF01352.22 EIW69384.1 - 0.035 13.5 1.4 0.068 12.6 1.0 1.4 1 0 0 1 1 1 0 KRAB box COX5A PF02284.11 EIW69385.1 - 2.6e-36 123.8 0.1 3.1e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Bud13 PF09736.4 EIW69386.1 - 1.1e-42 145.7 13.8 1.1e-42 145.7 9.5 2.3 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Herpes_LMP2 PF07415.6 EIW69386.1 - 1.9 6.9 3.5 2.7 6.5 2.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein zf-RING_4 PF14570.1 EIW69387.1 - 2.9e-16 58.7 10.2 4.3e-16 58.2 7.1 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EIW69387.1 - 1.1e-05 24.9 6.4 1.8e-05 24.2 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 EIW69387.1 - 0.0028 17.3 2.1 0.0028 17.3 1.5 1.5 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.1 EIW69387.1 - 0.0042 16.8 10.4 0.0062 16.3 7.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW69387.1 - 0.13 12.3 11.1 0.21 11.6 7.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW69387.1 - 0.55 10.0 9.2 0.81 9.4 6.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW69387.1 - 3.1 7.5 10.3 5 6.8 7.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lactamase_B_2 PF12706.2 EIW69391.1 - 7.5e-28 97.3 0.2 4e-27 95.0 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIW69391.1 - 3.9e-09 36.4 0.0 8.7e-09 35.2 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIW69391.1 - 0.0073 15.9 0.1 0.21 11.2 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Glyco_hydro_cc PF11790.3 EIW69392.1 - 2e-55 187.8 16.3 2.4e-55 187.5 11.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF814 PF05670.8 EIW69393.1 - 1e-19 70.1 0.0 2.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) NYN_YacP PF05991.6 EIW69393.1 - 0.2 11.3 4.2 0.36 10.5 2.9 1.5 1 1 0 1 1 1 0 YacP-like NYN domain ELYS PF13934.1 EIW69394.1 - 8.8e-45 153.1 0.2 2.5e-44 151.7 0.1 1.7 1 1 0 1 1 1 1 Nuclear pore complex assembly Arf PF00025.16 EIW69395.1 - 2.5e-66 222.2 0.0 2.8e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIW69395.1 - 1.6e-10 40.5 0.0 2.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIW69395.1 - 2.8e-10 39.4 0.2 4.5e-07 28.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EIW69395.1 - 1.5e-06 28.6 0.0 2.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW69395.1 - 2.4e-06 27.4 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EIW69395.1 - 8.1e-06 25.3 0.0 1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EIW69395.1 - 3.5e-05 23.0 0.0 3.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW69395.1 - 0.018 14.5 0.0 0.25 10.7 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EIW69395.1 - 0.057 12.9 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EIW69395.1 - 0.12 11.8 0.0 6.1 6.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Lysine_decarbox PF03641.9 EIW69396.1 - 5.9e-28 97.3 0.0 1.2e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase Aminotran_4 PF01063.14 EIW69396.1 - 1.9e-14 53.6 0.0 2.8e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV BCS1_N PF08740.6 EIW69397.1 - 8.2e-21 74.4 0.1 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIW69397.1 - 4.3e-20 72.2 0.0 2e-09 37.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW69397.1 - 3.8e-05 24.4 0.3 0.00029 21.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIW69397.1 - 0.00067 19.8 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW69397.1 - 0.00082 19.4 0.0 0.0023 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EIW69397.1 - 0.0024 17.3 0.0 0.0061 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RuvB_N PF05496.7 EIW69397.1 - 0.0027 16.7 0.0 0.0047 15.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EIW69397.1 - 0.0027 17.1 0.0 0.007 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW69397.1 - 0.0035 17.2 0.0 0.0085 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW69397.1 - 0.0038 16.9 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EIW69397.1 - 0.0071 16.0 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 EIW69397.1 - 0.014 15.6 1.9 0.029 14.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EIW69397.1 - 0.014 15.5 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.10 EIW69397.1 - 0.034 13.9 1.7 0.065 13.0 0.0 2.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EIW69397.1 - 0.043 14.1 0.3 0.27 11.5 0.0 2.5 3 0 0 3 3 2 0 ABC transporter DUF4291 PF14124.1 EIW69397.1 - 0.079 12.5 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) IstB_IS21 PF01695.12 EIW69397.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 EIW69397.1 - 0.31 11.3 0.0 0.31 11.3 0.0 2.7 2 1 0 2 2 1 0 AAA domain AAA PF00004.24 EIW69398.1 - 9.9e-18 64.6 0.0 4.4e-16 59.2 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EIW69398.1 - 7.4e-14 51.7 3.0 7.4e-14 51.7 2.1 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA_25 PF13481.1 EIW69398.1 - 0.00064 19.1 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW69398.1 - 0.00083 19.3 0.1 0.0047 16.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EIW69398.1 - 0.002 17.8 0.1 0.048 13.3 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIW69398.1 - 0.0026 18.5 0.0 0.0098 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW69398.1 - 0.006 16.0 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RuvB_N PF05496.7 EIW69398.1 - 0.0072 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIW69398.1 - 0.018 15.1 0.1 0.097 12.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EIW69398.1 - 0.028 14.0 0.1 0.33 10.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EIW69398.1 - 0.033 14.3 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 EIW69398.1 - 0.041 12.8 0.0 0.74 8.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) KaiC PF06745.8 EIW69398.1 - 0.052 12.6 0.0 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.22 EIW69398.1 - 0.068 13.4 0.2 0.47 10.7 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Cpn10 PF00166.16 EIW69399.1 - 2.5e-26 91.4 0.0 2.8e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.19 EIW69400.1 - 1.7e-117 392.9 6.7 2e-117 392.8 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lactonase PF10282.4 EIW69401.1 - 5.2e-46 157.3 0.0 6.5e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller KNOX1 PF03790.8 EIW69401.1 - 0.021 14.1 1.0 0.032 13.5 0.1 1.7 2 0 0 2 2 2 0 KNOX1 domain ACPS PF01648.15 EIW69402.1 - 4.7e-23 81.2 0.0 5.3e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Aminotran_1_2 PF00155.16 EIW69404.1 - 5.8e-19 68.2 0.0 7.3e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Zn_clus PF00172.13 EIW69405.1 - 3e-07 30.2 13.5 5.6e-07 29.3 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ING PF12998.2 EIW69406.1 - 1.7 8.9 6.1 6.2 7.1 4.2 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF3759 PF12585.3 EIW69407.1 - 2.8e-31 107.2 0.6 3.2e-31 107.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Sugar_tr PF00083.19 EIW69408.1 - 4.7e-118 394.6 28.2 5.4e-118 394.4 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW69408.1 - 2.1e-16 59.6 43.8 5.3e-12 45.1 15.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EIW69409.1 - 2.6e-32 112.0 0.0 4.1e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69409.1 - 1.2e-20 73.6 0.0 1.6e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PPP1R35_C PF15503.1 EIW69409.1 - 0.17 11.3 4.3 0.098 12.1 0.6 2.4 3 0 0 3 3 3 0 Protein phosphatase 1 regulatory subunit 35 C-terminus PQ-loop PF04193.9 EIW69410.1 - 5.7e-38 128.2 10.6 2.5e-19 68.5 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EIW69410.1 - 1.8 8.4 6.6 0.25 11.2 0.4 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange FA_hydroxylase PF04116.8 EIW69412.1 - 1.5e-18 67.2 15.8 2.5e-18 66.5 10.9 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Bromodomain PF00439.20 EIW69413.1 - 7.6e-24 83.4 0.2 1.4e-23 82.6 0.2 1.4 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EIW69413.1 - 2.7e-05 23.8 0.0 5.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Tau95 PF09734.4 EIW69414.1 - 2e-51 175.2 0.0 2.5e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit F-box-like PF12937.2 EIW69418.1 - 0.039 13.6 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 F-box-like CoA_transf_3 PF02515.12 EIW69419.1 - 4.5e-25 88.0 0.0 6.4e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Pal1 PF08316.6 EIW69420.1 - 6.5e-10 39.6 0.1 2.1e-09 37.9 0.1 1.9 1 0 0 1 1 1 1 Pal1 cell morphology protein MFS_1 PF07690.11 EIW69421.1 - 1.7e-39 135.5 40.3 1.7e-39 135.5 27.9 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW69421.1 - 0.00014 20.5 40.5 0.00059 18.5 12.7 3.7 4 1 0 4 4 4 2 Sugar (and other) transporter SKG6 PF08693.5 EIW69422.1 - 1.5e-05 24.2 0.3 2.3e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.9 EIW69422.1 - 0.027 14.2 1.4 0.027 14.2 0.9 1.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Glycophorin_A PF01102.13 EIW69422.1 - 0.066 12.9 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A DUF1183 PF06682.7 EIW69422.1 - 0.19 11.2 9.1 0.35 10.4 6.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) MLANA PF14991.1 EIW69422.1 - 0.22 11.5 2.1 0.38 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein melan-A PKD_channel PF08016.7 EIW69423.1 - 0.00013 20.5 15.3 0.00036 19.1 2.5 2.2 2 0 0 2 2 2 2 Polycystin cation channel DUF605 PF04652.11 EIW69424.1 - 0.015 14.6 6.7 0.021 14.2 4.6 1.1 1 0 0 1 1 1 0 Vta1 like CarbpepA_inh PF02977.10 EIW69425.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor DUF2420 PF10336.4 EIW69427.1 - 9.5e-11 41.3 0.0 1.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) SPATA6 PF14909.1 EIW69428.1 - 0.085 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 Glyco_transf_15 PF01793.11 EIW69429.1 - 2.5e-134 447.4 10.8 3.1e-134 447.1 7.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF2841 PF11001.3 EIW69431.1 - 2.5e-38 130.7 0.6 4.9e-38 129.8 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Pox_RNA_Pol_19 PF05320.7 EIW69431.1 - 0.28 10.8 3.7 0.35 10.6 0.7 2.1 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit ox_reductase_C PF08635.5 EIW69432.1 - 1.5e-75 251.3 0.1 2.3e-75 250.7 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EIW69432.1 - 3.5e-23 82.3 0.0 5.3e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.11 EIW69434.1 - 2.3e-24 85.7 21.1 4.6e-23 81.5 14.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW69434.1 - 1.3e-09 37.1 2.8 1.3e-09 37.1 2.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2723 PF11028.3 EIW69434.1 - 0.009 15.5 1.0 0.009 15.5 0.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) DUF4191 PF13829.1 EIW69434.1 - 0.2 10.7 0.7 0.42 9.6 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Fungal_trans PF04082.13 EIW69436.1 - 2e-16 59.6 0.0 3.5e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW69436.1 - 4.2e-07 29.7 11.5 6.9e-07 29.0 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EIW69436.1 - 0.12 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Hexokinase_1 PF00349.16 EIW69437.1 - 2.4e-67 226.2 0.0 3.5e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EIW69437.1 - 1.3e-65 220.9 0.0 1.9e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase SMC_N PF02463.14 EIW69438.1 - 3e-60 203.1 10.8 1.6e-59 200.7 7.5 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIW69438.1 - 1.8e-32 111.8 0.0 7e-32 109.9 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EIW69438.1 - 6.7e-17 62.3 0.0 2.1e-07 31.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW69438.1 - 1.8e-10 40.2 0.2 7.4e-09 35.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EIW69438.1 - 5.2e-10 39.9 79.1 7.1e-09 36.2 25.9 5.7 2 2 1 3 3 2 1 AAA domain AAA_15 PF13175.1 EIW69438.1 - 7.2e-06 25.2 0.0 7.2e-06 25.2 0.0 4.8 4 2 1 5 5 5 2 AAA ATPase domain AAA_13 PF13166.1 EIW69438.1 - 4.5e-05 22.1 11.9 4.5e-05 22.1 8.3 5.8 3 2 2 6 6 6 1 AAA domain Val_tRNA-synt_C PF10458.4 EIW69438.1 - 0.00013 21.9 1.1 0.00013 21.9 0.7 6.9 8 1 1 9 9 8 2 Valyl tRNA synthetase tRNA binding arm TMF_DNA_bd PF12329.3 EIW69438.1 - 0.0026 17.5 5.0 0.0026 17.5 3.5 8.2 5 2 2 7 7 7 3 TATA element modulatory factor 1 DNA binding Laminin_I PF06008.9 EIW69438.1 - 0.0054 16.0 17.5 0.0054 16.0 12.1 5.8 3 2 2 5 5 5 1 Laminin Domain I ABC_tran PF00005.22 EIW69438.1 - 0.027 14.7 0.0 0.027 14.7 0.0 5.9 4 2 0 4 4 3 0 ABC transporter Filament PF00038.16 EIW69438.1 - 0.062 12.7 82.0 0.04 13.3 9.2 5.8 4 1 0 4 4 4 0 Intermediate filament protein AAA_17 PF13207.1 EIW69438.1 - 1.4 9.7 0.0 1.4 9.7 0.0 4.9 4 2 0 4 4 3 0 AAA domain DUF1664 PF07889.7 EIW69438.1 - 1.5 8.6 30.3 5.5 6.8 1.1 6.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 EIW69438.1 - 1.6 7.8 22.4 3.4 6.7 1.1 5.1 4 1 1 5 5 5 0 Reovirus sigma C capsid protein Zn_clus PF00172.13 EIW69439.1 - 1.9e-06 27.6 8.9 3.5e-06 26.8 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIW69439.1 - 2.8e-05 23.1 0.0 4.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.23 EIW69440.1 - 7.8e-13 49.0 0.0 1.7e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 SET domain SWIM PF04434.12 EIW69441.1 - 5.3e-06 25.7 0.2 1e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger DUF1360 PF07098.6 EIW69441.1 - 0.22 11.2 0.9 0.55 9.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Prok-RING_1 PF14446.1 EIW69441.1 - 0.31 10.8 4.5 7.1 6.4 0.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 EIW69441.1 - 0.7 9.7 6.0 0.22 11.4 0.9 2.5 2 1 0 2 2 2 0 Ring finger domain Mg_trans_NIPA PF05653.9 EIW69442.1 - 2e-13 49.9 14.3 3.4e-07 29.5 2.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA DUF3328 PF11807.3 EIW69442.1 - 0.13 11.8 1.4 7.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF3357 PF11837.3 EIW69442.1 - 1.8 8.4 0.0 1.8 8.4 0.0 3.4 4 1 1 5 5 5 0 Domain of unknown function (DUF3357) ATP-synt_8 PF00895.15 EIW69442.1 - 6.7 7.0 10.6 9.5 6.5 0.2 4.1 4 0 0 4 4 4 0 ATP synthase protein 8 Ribosomal_L4 PF00573.17 EIW69443.1 - 4.9e-55 185.9 0.0 6.4e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.14 EIW69444.1 - 1.5e-36 125.3 0.4 1.7e-36 125.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Sad1_UNC PF07738.8 EIW69445.1 - 3e-23 82.1 0.0 2e-22 79.4 0.0 2.1 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal EzrA PF06160.7 EIW69445.1 - 0.0006 18.1 1.2 0.0021 16.3 0.4 1.8 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Tropomyosin PF00261.15 EIW69445.1 - 0.0043 16.1 0.8 0.93 8.5 0.2 2.3 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 EIW69445.1 - 0.01 15.7 1.1 0.01 15.7 0.8 2.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EIW69445.1 - 0.036 13.9 2.7 0.14 12.0 0.9 2.4 1 1 1 2 2 2 0 Tropomyosin like Cytochrom_B562 PF07361.6 EIW69445.1 - 0.065 13.6 2.3 0.082 13.3 0.3 2.1 2 0 0 2 2 2 0 Cytochrome b562 Reo_sigmaC PF04582.7 EIW69445.1 - 0.12 11.5 1.7 0.11 11.6 0.1 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EIW69445.1 - 0.5 9.9 4.6 0.48 9.9 1.0 2.3 2 1 0 2 2 2 0 IncA protein TBPIP PF07106.8 EIW69445.1 - 0.54 9.7 2.3 1.5 8.3 0.3 2.3 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4385 PF14328.1 EIW69446.1 - 2.3e-39 134.6 1.5 4e-39 133.8 1.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4385) Complex1_LYR_2 PF13233.1 EIW69446.1 - 0.018 15.5 0.0 0.031 14.7 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like DUF2535 PF10751.4 EIW69446.1 - 0.15 12.2 0.4 0.25 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2535) GPI-anchored PF10342.4 EIW69447.1 - 9.3e-06 26.0 0.1 9.3e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Methyltransf_23 PF13489.1 EIW69448.1 - 1.5e-06 28.0 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW69448.1 - 2.1e-06 27.0 0.0 3.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EIW69448.1 - 5.5e-06 26.7 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW69448.1 - 2.4e-05 24.8 0.0 4.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIW69448.1 - 0.0048 16.5 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.1 EIW69448.1 - 0.015 14.9 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EIW69448.1 - 0.037 13.4 0.0 0.14 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EIW69448.1 - 0.062 12.3 0.0 0.69 8.9 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_26 PF13659.1 EIW69448.1 - 0.063 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EIW69448.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIW69448.1 - 0.19 12.2 0.0 1 9.8 0.0 2.3 2 1 0 2 2 1 0 Methyltransferase domain Abhydrolase_6 PF12697.2 EIW69449.1 - 7.4e-21 75.0 0.5 1.3e-20 74.2 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW69449.1 - 1.7e-16 60.3 0.1 1.1e-15 57.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW69449.1 - 3.6e-05 23.4 0.1 0.00071 19.2 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIW69449.1 - 0.0004 20.1 0.0 0.0009 19.0 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EIW69449.1 - 0.00058 19.3 0.0 0.038 13.4 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EIW69449.1 - 0.00064 19.0 0.0 0.52 9.5 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EIW69449.1 - 0.019 14.3 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EIW69449.1 - 0.035 13.5 0.1 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Trehalase PF01204.13 EIW69450.1 - 1.4e-162 541.9 0.0 1.7e-162 541.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EIW69450.1 - 3.2e-13 48.7 0.1 5.7e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.1 EIW69450.1 - 0.01 15.6 0.0 8.4 6.3 0.0 3.3 3 0 0 3 3 3 0 Ribbon-helix-helix domain Tubulin PF00091.20 EIW69451.1 - 5.6e-68 228.9 0.0 7.5e-68 228.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIW69451.1 - 4e-47 159.3 0.0 6.2e-47 158.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EIW69451.1 - 0.00086 18.8 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EIW69451.1 - 0.085 12.4 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Pkinase PF00069.20 EIW69453.1 - 2.2e-45 154.8 0.0 6e-31 107.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69453.1 - 2.1e-21 76.2 0.0 1.4e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW69453.1 - 4.1e-07 29.2 0.0 0.015 14.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EIW69453.1 - 0.00026 20.7 0.0 0.00063 19.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family KilA-N PF04383.8 EIW69454.1 - 0.017 14.7 0.0 0.23 11.0 0.0 2.2 1 1 0 1 1 1 0 KilA-N domain Ribosomal_L10 PF00466.15 EIW69455.1 - 9.6e-17 60.7 0.0 1.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 zf-C2H2_4 PF13894.1 EIW69456.1 - 0.00044 20.3 2.2 0.0073 16.5 0.0 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW69456.1 - 0.02 15.1 2.5 0.07 13.5 0.0 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW69456.1 - 5.2 7.5 5.8 0.55 10.6 0.1 2.4 3 0 0 3 3 3 0 Zinc-finger double domain Pkinase PF00069.20 EIW69457.1 - 6.1e-40 137.0 0.0 1.7e-39 135.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69457.1 - 1.7e-17 63.3 0.0 7.5e-10 38.3 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW69457.1 - 6.6e-07 28.5 0.0 0.00036 19.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EIW69457.1 - 0.0057 16.4 0.2 0.05 13.3 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family PolyA_pol PF01743.15 EIW69458.1 - 2.3e-24 86.0 0.0 8.9e-24 84.1 0.0 2.0 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EIW69458.1 - 0.00013 21.4 0.0 0.00031 20.2 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A ARGLU PF15346.1 EIW69458.1 - 0.057 13.1 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 UPF0047 PF01894.12 EIW69459.1 - 1.8e-36 124.4 0.0 1.9e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Xylanase PF13201.1 EIW69459.1 - 0.14 10.8 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Putative glycoside hydrolase xylanase DUF2120 PF09893.4 EIW69460.1 - 5.9 6.8 6.2 6 6.7 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) MULE PF10551.4 EIW69461.1 - 3e-13 49.7 1.4 1.2e-10 41.4 0.2 3.6 2 1 0 2 2 2 1 MULE transposase domain UCH PF00443.24 EIW69461.1 - 1.1e-09 37.7 0.0 3.1e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW69461.1 - 0.034 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase OGG_N PF07934.7 EIW69462.1 - 1.1e-21 76.9 0.0 1.9e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EIW69462.1 - 4.7e-06 26.8 0.0 8.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EIW69462.1 - 0.038 13.6 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Na_Ca_ex PF01699.19 EIW69463.1 - 9e-41 138.7 29.9 1.3e-21 76.6 4.2 3.4 3 1 0 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.7 EIW69463.1 - 0.029 14.2 1.1 0.082 12.7 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Ribosomal_L13 PF00572.13 EIW69466.1 - 2.3e-39 134.3 0.0 2.8e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 MLTD_N PF06474.7 EIW69466.1 - 0.18 12.0 0.2 0.18 12.0 0.2 1.9 2 0 0 2 2 2 0 MltD lipid attachment motif Pkinase PF00069.20 EIW69468.1 - 3.1e-63 213.3 0.0 4.1e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69468.1 - 3.8e-35 121.2 0.0 5.3e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW69468.1 - 7.1e-08 31.7 0.0 1.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW69468.1 - 0.0019 17.9 0.4 0.0041 16.8 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW69468.1 - 0.013 14.6 0.1 0.045 12.7 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPE65 PF03055.10 EIW69469.1 - 1.5e-100 337.1 0.0 1.8e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein LSM PF01423.17 EIW69470.1 - 2e-16 59.3 0.4 2.7e-16 58.8 0.2 1.2 1 0 0 1 1 1 1 LSM domain Rep_fac-A_3 PF08661.6 EIW69471.1 - 5.9e-22 77.6 0.0 6.6e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 zf-LYAR PF08790.6 EIW69472.1 - 1.9e-12 46.6 6.8 1.9e-12 46.6 4.7 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF3350 PF11830.3 EIW69472.1 - 0.072 13.1 1.3 0.16 11.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) Prok-RING_1 PF14446.1 EIW69472.1 - 1.1 9.0 7.7 8.1 6.2 5.3 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CXXC PF02008.15 EIW69472.1 - 5.9 6.7 8.3 0.34 10.7 1.8 1.9 2 0 0 2 2 2 0 CXXC zinc finger domain Response_reg PF00072.19 EIW69473.1 - 8.2e-23 80.5 0.0 1.7e-16 60.2 0.0 2.7 3 0 0 3 3 3 2 Response regulator receiver domain Pkinase PF00069.20 EIW69474.1 - 2e-66 223.8 0.0 2.4e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69474.1 - 1.9e-27 95.9 0.0 2.7e-27 95.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW69474.1 - 2.6e-07 29.8 0.0 2e-06 26.9 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EIW69474.1 - 4.2e-05 22.7 0.1 6.9e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW69474.1 - 0.00075 19.2 0.3 0.16 11.6 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EIW69474.1 - 0.0015 17.8 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Cytokin_check_N PF10407.4 EIW69474.1 - 0.013 15.1 0.5 0.079 12.5 0.0 2.5 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus Aminotran_1_2 PF00155.16 EIW69475.1 - 4.9e-09 35.6 0.0 3.9e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II Prok-RING_1 PF14446.1 EIW69476.1 - 0.038 13.7 0.2 0.038 13.7 0.1 1.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DNA_ligase_ZBD PF03119.11 EIW69476.1 - 0.85 9.3 6.4 0.91 9.2 0.7 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_5 PF14634.1 EIW69476.1 - 2 8.1 6.0 13 5.5 4.2 2.2 1 1 0 1 1 1 0 zinc-RING finger domain Acyltransferase PF01553.16 EIW69477.1 - 3.2e-22 78.3 0.0 5e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase CBS PF00571.23 EIW69478.1 - 0.00012 21.8 0.1 2 8.2 0.0 4.6 5 0 0 5 5 5 2 CBS domain Proteasome PF00227.21 EIW69479.1 - 2e-42 144.6 0.1 2.3e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Beta-TrCP_D PF12125.3 EIW69479.1 - 0.13 11.8 0.9 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 D domain of beta-TrCP Fungal_trans PF04082.13 EIW69482.1 - 6.3e-05 21.9 0.0 0.00012 21.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW69482.1 - 7.2e-05 22.6 8.8 0.00015 21.5 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPN7 PF10602.4 EIW69482.1 - 0.088 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Sugar_tr PF00083.19 EIW69483.1 - 9.6e-70 235.3 20.6 1.1e-69 235.1 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW69483.1 - 3.9e-11 42.2 27.7 3.9e-11 42.2 19.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EIW69483.1 - 1.1e-10 40.5 12.1 6.1e-08 31.4 2.5 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein LAMTOR PF15454.1 EIW69484.1 - 0.21 11.9 1.0 0.38 11.0 0.7 1.4 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator zf-C3HC4_3 PF13920.1 EIW69485.1 - 1.1e-12 47.3 9.0 1.1e-12 47.3 6.2 2.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EIW69485.1 - 2e-07 30.7 1.1 2e-07 30.7 0.8 2.8 2 1 0 2 2 1 1 FYVE zinc finger zf-C3HC4_2 PF13923.1 EIW69485.1 - 0.00036 20.4 10.3 0.00036 20.4 7.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW69485.1 - 0.00059 19.6 9.2 0.00059 19.6 6.3 2.6 3 0 0 3 3 3 1 Ring finger domain Armet PF10208.4 EIW69485.1 - 0.0015 18.1 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding OrfB_Zn_ribbon PF07282.6 EIW69485.1 - 0.0038 16.8 1.7 0.79 9.4 0.4 2.6 2 0 0 2 2 2 1 Putative transposase DNA-binding domain zf-P11 PF03854.9 EIW69485.1 - 0.0058 16.0 4.6 0.0058 16.0 3.2 3.1 3 1 1 4 4 3 1 P-11 zinc finger HeH PF12949.2 EIW69485.1 - 0.016 14.7 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 HeH/LEM domain SAP PF02037.22 EIW69485.1 - 0.055 12.9 0.0 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 SAP domain FYVE_2 PF02318.11 EIW69485.1 - 0.13 12.1 0.1 0.13 12.1 0.1 3.5 4 0 0 4 4 4 0 FYVE-type zinc finger zf-H2C2_2 PF13465.1 EIW69485.1 - 1.8 9.0 6.5 12 6.4 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-RING_5 PF14634.1 EIW69485.1 - 4.3 7.1 23.3 0.81 9.4 6.4 2.9 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_4 PF14570.1 EIW69485.1 - 5.9 6.5 23.7 1.1 8.8 3.0 2.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Atg14 PF10186.4 EIW69486.1 - 7.2e-16 57.9 0.1 1.3e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 EIW69486.1 - 0.042 13.6 10.2 0.092 12.5 7.1 1.5 1 0 0 1 1 1 0 Tropomyosin like PEARLI-4 PF05278.7 EIW69486.1 - 0.16 11.2 5.9 0.29 10.4 4.1 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Phlebovirus_NSM PF07246.6 EIW69486.1 - 0.21 10.7 3.3 0.35 9.9 2.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M V_ATPase_I PF01496.14 EIW69486.1 - 2 6.1 3.8 2.9 5.6 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EIW69486.1 - 3.4 6.6 6.7 52 2.7 5.5 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 DivIC PF04977.10 EIW69486.1 - 3.9 7.0 7.9 0.8 9.2 0.1 2.9 1 1 2 3 3 3 0 Septum formation initiator Syntaxin PF00804.20 EIW69486.1 - 5.7 7.1 9.1 37 4.5 6.3 2.3 1 1 0 1 1 1 0 Syntaxin GTP_EFTU PF00009.22 EIW69488.1 - 1.7e-31 109.1 0.0 7.2e-31 107.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EIW69488.1 - 1.2e-14 54.0 0.0 6.5e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EIW69488.1 - 5.4e-09 36.0 5.3 1.2e-07 31.7 0.0 3.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW69488.1 - 1.9e-06 27.8 0.0 6.1e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Stm1_N PF09598.5 EIW69488.1 - 0.016 15.9 2.5 0.016 15.9 1.7 8.5 7 1 1 8 8 8 0 Stm1 Ras PF00071.17 EIW69488.1 - 0.021 14.2 0.0 0.064 12.6 0.0 1.9 1 0 0 1 1 1 0 Ras family ATP_bind_1 PF03029.12 EIW69488.1 - 0.089 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein mRNA_cap_enzyme PF01331.14 EIW69489.1 - 1.3e-46 158.7 0.3 2e-46 158.1 0.2 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EIW69489.1 - 6.4e-20 71.4 0.3 1.8e-19 70.0 0.2 1.8 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EIW69489.1 - 2.7e-10 39.9 0.1 9.1e-09 34.9 0.0 2.5 2 1 0 2 2 2 1 ATP dependent DNA ligase domain PALP PF00291.20 EIW69490.1 - 3.1e-20 72.6 0.0 1.4e-19 70.4 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.1 EIW69490.1 - 1e-08 35.0 0.0 2.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus Nup96 PF12110.3 EIW69491.1 - 3.9e-80 269.0 0.0 5.4e-80 268.6 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EIW69491.1 - 1.2e-45 154.7 0.0 2.1e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EIW69491.1 - 4e-06 27.0 308.5 0.0014 18.7 30.3 8.7 2 2 5 7 7 7 4 Nucleoporin FG repeat region Ion_trans PF00520.26 EIW69492.1 - 6e-18 64.8 12.3 6e-18 64.8 8.5 1.6 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EIW69492.1 - 5.1e-11 42.1 8.6 7.3e-11 41.6 3.4 2.7 2 1 0 2 2 2 1 Ion channel zf-CCCH PF00642.19 EIW69493.1 - 1.3e-11 43.8 22.6 0.00083 18.9 0.5 4.8 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 EIW69493.1 - 1.3e-05 24.8 1.0 4.6e-05 23.1 0.7 2.1 1 0 0 1 1 1 1 Zinc knuckle M_domain PF12938.2 EIW69493.1 - 2.8 7.6 5.8 4.2 7.1 4.0 1.1 1 0 0 1 1 1 0 M domain of GW182 DEAD PF00270.24 EIW69494.1 - 6e-42 143.0 0.5 1e-41 142.2 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW69494.1 - 1.2e-21 76.3 0.0 2.2e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EIW69494.1 - 1.9e-20 72.1 0.5 3.7e-20 71.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EIW69494.1 - 0.021 14.6 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW69494.1 - 0.045 13.8 0.5 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Utp12 PF04003.7 EIW69495.1 - 1e-07 31.8 0.5 3.8e-07 29.9 0.3 1.9 1 1 0 1 1 1 1 Dip2/Utp12 Family TFIIA PF03153.8 EIW69495.1 - 0.00025 21.0 0.4 0.00043 20.2 0.1 1.5 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Ricin_B_lectin PF00652.17 EIW69496.1 - 2.5e-21 75.9 15.0 1.5e-08 34.7 0.1 7.3 5 2 1 6 6 6 4 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIW69496.1 - 5.1e-06 26.8 1.5 0.017 15.5 0.0 4.6 6 0 0 6 6 6 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIW69497.1 - 1.1e-10 41.6 11.7 1.2e-05 25.2 1.0 4.2 2 2 1 3 3 3 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIW69497.1 - 0.066 13.5 0.0 2.1 8.7 0.0 2.8 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Hirudin PF00713.12 EIW69497.1 - 0.26 11.4 2.5 0.57 10.3 0.5 2.5 3 0 0 3 3 3 0 Hirudin Ricin_B_lectin PF00652.17 EIW69498.1 - 4.1e-24 84.9 28.0 1e-08 35.2 1.1 5.0 4 1 0 5 5 5 4 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.17 EIW69499.1 - 1.6e-13 50.7 0.2 9.2e-05 22.4 0.0 4.5 3 2 1 4 4 4 2 Ricin-type beta-trefoil lectin domain XPG_N PF00752.12 EIW69500.1 - 1.2e-06 28.6 0.0 2.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Pacs-1 PF10254.4 EIW69500.1 - 0.023 13.3 1.0 0.051 12.2 0.7 1.5 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Ureidogly_hydro PF04115.7 EIW69500.1 - 0.088 12.1 0.2 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 Ureidoglycolate hydrolase RNA_pol_I_A49 PF06870.7 EIW69501.1 - 1.2e-70 238.0 0.0 1.4e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor RNA_pol_L_2 PF13656.1 EIW69503.1 - 2.5e-28 97.3 0.0 4.3e-28 96.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EIW69503.1 - 1.8e-12 46.1 0.0 2.9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Far-17a_AIG1 PF04750.9 EIW69504.1 - 2.1e-40 138.0 5.4 2.4e-40 137.8 3.7 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Molybdopterin PF00384.17 EIW69506.1 - 1.2e-64 218.6 0.0 6.7e-62 209.6 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EIW69506.1 - 2e-19 69.1 0.4 4.5e-19 68.0 0.3 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EIW69506.1 - 2.5e-18 65.0 0.2 6.4e-18 63.6 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EIW69506.1 - 2.9e-14 52.9 0.0 7.2e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EIW69506.1 - 2.3e-08 33.6 0.9 2.3e-08 33.6 0.6 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EIW69506.1 - 0.043 13.5 0.1 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EIW69506.1 - 0.14 11.7 1.1 4 7.2 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 EIW69506.1 - 0.34 10.8 3.5 0.43 10.5 1.0 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain MOR2-PAG1_N PF14222.1 EIW69507.1 - 1.6e-79 268.0 0.2 4.9e-62 210.3 0.1 2.8 2 1 1 3 3 3 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EIW69507.1 - 2.4e-74 250.4 0.3 2.4e-74 250.4 0.2 2.8 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EIW69507.1 - 2.4e-18 65.1 0.0 3.6e-12 44.7 0.0 4.1 4 0 0 4 4 4 4 Cell morphogenesis central region HEAT_2 PF13646.1 EIW69507.1 - 3.5e-08 33.6 1.1 0.063 13.5 0.0 5.8 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EIW69507.1 - 0.0033 17.3 0.1 15 5.9 0.0 4.5 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 EIW69507.1 - 0.49 10.9 6.9 1.8 9.1 0.0 5.6 6 0 0 6 6 6 0 HEAT-like repeat Pro_isomerase PF00160.16 EIW69508.1 - 1e-44 152.4 0.2 1.2e-44 152.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNase_H PF00075.19 EIW69509.1 - 1.9e-08 34.6 0.1 3.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNase H Lactamase_B PF00753.22 EIW69509.1 - 0.044 13.4 0.2 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Nucleoplasmin PF03066.10 EIW69509.1 - 0.086 12.3 0.7 0.16 11.4 0.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sec1 PF00995.18 EIW69510.1 - 6e-133 444.4 0.0 6.9e-133 444.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family adh_short PF00106.20 EIW69511.1 - 4.1e-31 108.1 0.4 5.9e-31 107.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW69511.1 - 4.8e-12 46.1 0.0 6.3e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW69511.1 - 1.6e-10 40.9 0.3 2.2e-10 40.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW69511.1 - 3.6e-05 23.3 0.3 5.4e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIW69511.1 - 0.00031 20.4 0.1 0.00074 19.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EIW69511.1 - 0.0011 17.8 0.4 0.0015 17.5 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 EIW69511.1 - 0.0024 17.0 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EIW69511.1 - 0.0024 17.9 0.2 0.004 17.1 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EIW69511.1 - 0.0027 16.7 0.0 0.0049 15.9 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EIW69511.1 - 0.0072 15.9 0.3 0.014 15.0 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EIW69511.1 - 0.016 14.2 0.1 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.16 EIW69511.1 - 0.029 13.9 1.2 0.083 12.4 0.8 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.8 EIW69511.1 - 0.049 12.8 0.3 0.079 12.1 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.15 EIW69511.1 - 0.054 13.5 1.4 0.067 13.2 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MobB PF03205.9 EIW69512.1 - 0.00038 20.1 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EIW69512.1 - 0.00079 18.2 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_14 PF13173.1 EIW69512.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EIW69512.1 - 0.0014 18.2 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EIW69512.1 - 0.0023 18.7 0.0 0.0039 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW69512.1 - 0.004 17.0 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW69512.1 - 0.0042 16.8 0.0 0.12 12.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EIW69512.1 - 0.0054 15.8 0.0 0.016 14.2 0.0 1.8 1 1 1 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 EIW69512.1 - 0.0057 16.8 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 EIW69512.1 - 0.007 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EIW69512.1 - 0.0089 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EIW69512.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EIW69512.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIW69512.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 EIW69512.1 - 0.019 14.6 0.2 0.042 13.5 0.1 1.6 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EIW69512.1 - 0.038 13.6 0.0 0.084 12.5 0.0 1.6 2 0 0 2 2 1 0 Archaeal ATPase AAA_35 PF14516.1 EIW69512.1 - 0.06 11.9 0.0 0.088 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 EIW69512.1 - 0.082 12.8 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIW69512.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EIW69512.1 - 0.083 13.1 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 EIW69512.1 - 0.092 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EIW69512.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain zf-Apc11 PF12861.2 EIW69513.1 - 3.3e-39 132.6 6.0 4.4e-39 132.2 4.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EIW69513.1 - 1.7e-28 98.4 8.3 2.4e-28 98.0 5.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EIW69513.1 - 0.00011 21.9 14.8 0.00036 20.2 10.3 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIW69513.1 - 0.067 12.8 13.7 0.34 10.5 9.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW69513.1 - 0.16 11.7 12.9 7 6.4 9.5 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.3 EIW69513.1 - 0.18 11.3 4.2 0.34 10.4 2.9 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 EIW69513.1 - 0.21 11.6 12.8 1.3 9.0 8.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EIW69513.1 - 2.2 8.3 8.7 6.3 6.8 6.0 1.8 1 1 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 EIW69513.1 - 8.4 6.4 13.2 25 4.9 9.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain TilS_C PF11734.3 EIW69516.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 TilS substrate C-terminal domain TRAM_LAG1_CLN8 PF03798.11 EIW69517.1 - 6.2e-35 120.5 18.2 6.2e-35 120.5 12.6 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EIW69517.1 - 1.5e-10 40.3 0.0 1.5e-10 40.3 0.0 2.6 3 0 0 3 3 3 1 TRAM1-like protein RRM_1 PF00076.17 EIW69518.1 - 5.2e-13 48.4 0.1 1.1e-12 47.3 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW69518.1 - 3.2e-10 39.7 0.0 4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW69518.1 - 1.2e-07 31.5 0.0 1.6e-07 31.2 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EMP24_GP25L PF01105.19 EIW69519.1 - 3e-38 131.3 0.0 3.3e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD tRNA-synt_1e PF01406.14 EIW69520.1 - 3e-121 404.1 0.0 4.8e-121 403.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EIW69520.1 - 2.1e-09 36.5 0.5 8.2e-05 21.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EIW69520.1 - 7.4e-06 24.2 1.6 0.00049 18.2 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 EIW69520.1 - 0.00092 19.4 0.0 0.0024 18.0 0.0 1.7 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.13 EIW69520.1 - 0.0022 16.7 0.0 1.3 7.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) Pmp3 PF01679.12 EIW69521.1 - 2.3e-21 75.2 7.9 2.9e-21 74.9 5.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF605 PF04652.11 EIW69522.1 - 0.92 8.8 5.6 1 8.7 3.9 1.0 1 0 0 1 1 1 0 Vta1 like SRPRB PF09439.5 EIW69523.1 - 1.4e-21 76.5 0.0 3e-21 75.4 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EIW69523.1 - 2.2e-11 43.5 0.0 5.1e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIW69523.1 - 3.1e-10 40.5 0.0 7.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW69523.1 - 5.6e-09 35.9 0.1 8.3e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EIW69523.1 - 1.6e-08 34.0 0.0 2.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW69523.1 - 2e-06 27.1 0.0 3.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EIW69523.1 - 2.7e-05 23.6 0.0 5.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Ras family FeoB_N PF02421.13 EIW69523.1 - 0.00011 21.5 0.1 0.00024 20.4 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.15 EIW69523.1 - 0.0067 15.1 0.2 0.39 9.3 0.0 2.6 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.1 EIW69523.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EIW69523.1 - 0.013 15.7 0.1 0.071 13.3 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EIW69523.1 - 0.018 15.3 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW69523.1 - 0.021 14.3 0.2 0.044 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EIW69523.1 - 0.023 14.1 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EIW69523.1 - 0.039 13.6 0.1 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EIW69523.1 - 0.095 11.8 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIW69523.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EIW69523.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MULE PF10551.4 EIW69524.1 - 2.4e-13 50.0 1.4 1.1e-10 41.5 0.2 3.6 2 1 0 2 2 2 1 MULE transposase domain UCH PF00443.24 EIW69524.1 - 1.9e-09 37.0 0.0 4.9e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW69524.1 - 0.035 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase FlxA PF14282.1 EIW69525.1 - 0.0043 16.9 3.8 0.0043 16.9 2.6 3.6 2 1 0 3 3 3 1 FlxA-like protein Cofilin_ADF PF00241.15 EIW69526.1 - 6.1e-14 52.0 0.1 6.9e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CLASP_N PF12348.3 EIW69527.1 - 0.0016 17.8 16.6 0.0062 15.9 1.0 4.6 5 0 0 5 5 5 2 CLASP N terminal HEAT PF02985.17 EIW69527.1 - 0.0017 18.2 1.9 1.7 8.9 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.18 EIW69527.1 - 0.066 13.0 1.9 45 4.0 0.0 4.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat dCMP_cyt_deam_1 PF00383.17 EIW69528.1 - 3.2e-24 84.5 0.7 4.8e-24 83.9 0.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 EIW69528.1 - 0.00016 22.5 0.0 0.00024 21.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EIW69528.1 - 0.034 14.1 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIW69528.1 - 0.089 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF221 PF02714.10 EIW69529.1 - 3.9e-95 318.4 17.7 3.9e-95 318.4 12.3 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIW69529.1 - 1e-33 116.1 2.2 3e-33 114.5 1.5 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EIW69529.1 - 3.8e-16 58.7 0.0 8.2e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EIW69529.1 - 9.4e-09 35.6 0.0 1.8e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) 2-oxoacid_dh PF00198.18 EIW69530.1 - 2.2e-79 265.9 0.1 3e-79 265.5 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIW69530.1 - 6.8e-20 70.4 2.0 1.4e-19 69.5 1.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EIW69530.1 - 2.2e-05 23.9 0.1 0.001 18.6 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 EIW69530.1 - 0.0011 19.3 0.1 0.22 11.8 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 EIW69530.1 - 0.0024 17.0 8.6 0.014 14.5 4.5 2.4 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 EIW69530.1 - 0.0026 17.4 0.2 0.0067 16.1 0.2 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein DUF3614 PF12267.3 EIW69530.1 - 0.094 12.9 0.8 0.7 10.1 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3614) Pox_P4B PF03292.9 EIW69530.1 - 0.11 10.3 0.7 0.19 9.6 0.5 1.4 1 0 0 1 1 1 0 Poxvirus P4B major core protein YL1 PF05764.8 EIW69530.1 - 0.13 11.8 18.1 0.19 11.3 12.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TLP-20 PF06088.6 EIW69530.1 - 0.2 11.2 3.2 0.4 10.3 2.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2201_N PF13203.1 EIW69530.1 - 1.5 7.9 10.2 2.2 7.3 7.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1510 PF07423.6 EIW69530.1 - 2.4 7.4 17.2 3.9 6.7 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4551 PF15087.1 EIW69530.1 - 2.6 6.3 10.0 3.5 5.8 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RR_TM4-6 PF06459.7 EIW69530.1 - 3 7.6 17.7 4.3 7.1 12.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.5 EIW69530.1 - 5.6 5.2 6.6 7.3 4.8 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-CCHC PF00098.18 EIW69532.1 - 0.001 18.8 2.2 0.001 18.8 1.5 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 EIW69532.1 - 0.037 13.7 0.5 0.15 11.7 0.5 1.9 2 0 0 2 2 2 0 Zinc knuckle DUF4219 PF13961.1 EIW69532.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) TniB PF05621.6 EIW69533.1 - 0.018 13.8 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein SDA1 PF05285.7 EIW69535.1 - 3.2 6.9 8.2 3.8 6.7 5.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EIW69535.1 - 4.7 5.0 7.8 6 4.6 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family ABC_membrane PF00664.18 EIW69536.1 - 3.1e-69 233.4 21.3 3.8e-35 121.6 3.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW69536.1 - 3.3e-66 221.7 0.0 3.8e-34 117.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW69536.1 - 7.5e-14 52.3 0.1 0.0023 17.9 0.0 4.4 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 EIW69536.1 - 1.9e-13 50.1 3.3 0.00025 20.3 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIW69536.1 - 4.4e-11 43.1 0.9 3.5e-05 23.8 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EIW69536.1 - 4.9e-11 43.5 0.0 4.7e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EIW69536.1 - 5.9e-10 38.3 1.0 3.5e-05 22.5 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_18 PF13238.1 EIW69536.1 - 1.5e-08 35.0 0.0 0.0041 17.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EIW69536.1 - 3.9e-08 33.1 0.2 0.069 12.5 0.0 4.1 4 0 0 4 4 4 2 AAA-like domain AAA_29 PF13555.1 EIW69536.1 - 5.1e-08 32.3 0.3 0.0037 16.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EIW69536.1 - 2.9e-07 30.6 4.1 0.0019 18.3 0.3 3.9 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIW69536.1 - 3.7e-07 29.7 0.0 0.0084 15.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 EIW69536.1 - 4e-07 29.6 0.5 0.58 9.5 0.0 4.3 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_5 PF07728.9 EIW69536.1 - 4.1e-07 29.8 0.0 0.0077 15.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIW69536.1 - 1.3e-06 28.3 0.0 0.09 12.6 0.0 3.7 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 EIW69536.1 - 3.9e-06 26.1 0.0 0.029 13.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EIW69536.1 - 4.3e-06 26.4 0.0 0.41 10.2 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EIW69536.1 - 3.3e-05 24.2 0.0 0.068 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EIW69536.1 - 0.00017 20.7 0.0 0.064 12.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.1 EIW69536.1 - 0.00029 20.6 2.3 0.86 9.5 0.7 3.8 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EIW69536.1 - 0.00034 20.1 0.3 0.73 9.3 0.0 2.9 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 EIW69536.1 - 0.00052 20.0 0.3 0.55 10.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW69536.1 - 0.00053 20.1 0.0 0.46 10.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.1 EIW69536.1 - 0.00089 19.1 2.8 2 8.2 0.0 3.6 4 0 0 4 4 3 2 AAA domain APS_kinase PF01583.15 EIW69536.1 - 0.001 18.7 0.0 0.87 9.2 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase PRK PF00485.13 EIW69536.1 - 0.0017 17.9 0.0 0.23 10.9 0.0 2.8 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EIW69536.1 - 0.0028 17.8 0.1 1.7 8.8 0.0 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EIW69536.1 - 0.003 17.4 0.2 2.8 7.6 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 G-alpha PF00503.15 EIW69536.1 - 0.0055 15.4 0.0 0.85 8.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit NACHT PF05729.7 EIW69536.1 - 0.01 15.5 0.2 5.3 6.6 0.1 2.8 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 EIW69536.1 - 0.011 15.1 0.0 0.29 10.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 EIW69536.1 - 0.013 15.2 0.0 7.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 EIW69536.1 - 0.014 14.5 0.0 2.8 7.0 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EIW69536.1 - 0.015 15.3 0.0 7.8 6.5 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EIW69536.1 - 0.026 14.0 0.0 5.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EIW69536.1 - 0.027 13.3 0.1 2 7.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain CbiA PF01656.18 EIW69536.1 - 0.052 12.9 0.0 0.8 9.0 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain CPT PF07931.7 EIW69536.1 - 0.057 13.0 0.1 13 5.3 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.4 EIW69536.1 - 0.06 12.3 0.2 9.4 5.0 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Synapsin_N PF10581.4 EIW69536.1 - 0.068 12.9 0.0 7.5 6.4 0.0 2.8 2 0 0 2 2 2 0 Synapsin N-terminal DUF3987 PF13148.1 EIW69536.1 - 0.16 10.4 1.0 2.7 6.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_13 PF13166.1 EIW69536.1 - 0.19 10.1 0.0 6.9 5.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EIW69536.1 - 0.68 8.5 0.5 1.4 7.4 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MR_MLE_C PF13378.1 EIW69537.1 - 3.2e-16 59.2 0.0 6.7e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EIW69537.1 - 1.6e-12 47.7 0.1 2.5e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EIW69537.1 - 9.9e-08 31.9 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain ubiquitin PF00240.18 EIW69538.1 - 2.9e-14 52.2 0.3 5.2e-14 51.4 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.26 EIW69538.1 - 7.2e-08 32.0 1.2 9.6e-08 31.6 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 EIW69538.1 - 6e-06 25.8 0.1 2.6e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 EIW69538.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 CUE domain Phage_tail_X PF05489.7 EIW69538.1 - 0.023 14.1 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X DUF2407 PF10302.4 EIW69538.1 - 0.054 13.6 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EIW69538.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 EIW69538.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain UDP-g_GGTase PF06427.6 EIW69539.1 - 3.5e-55 186.5 0.0 5.9e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EIW69539.1 - 1.2e-08 34.6 0.1 2.8e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 Ku PF02735.11 EIW69540.1 - 4.1e-22 78.5 0.0 1.1e-21 77.2 0.0 1.6 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EIW69540.1 - 1e-14 54.4 0.0 2.6e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 EIW69540.1 - 2e-07 31.2 0.0 3.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_N PF03731.10 EIW69540.1 - 1.1e-06 28.3 0.0 5.3e-06 26.0 0.0 2.1 2 1 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.23 EIW69540.1 - 0.0011 18.6 0.0 0.0037 17.0 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain ACDC PF14733.1 EIW69540.1 - 0.17 12.0 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 AP2-coincident C-terminal Xpo1 PF08389.7 EIW69541.1 - 0.098 12.5 0.5 13 5.6 0.2 2.2 2 0 0 2 2 2 0 Exportin 1-like protein Pecanex_C PF05041.10 EIW69542.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Pecanex protein (C-terminus) Het-C PF07217.6 EIW69543.1 - 9.4e-223 740.7 0.0 1.2e-222 740.4 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Zip PF02535.17 EIW69543.1 - 0.36 9.7 3.5 0.66 8.9 2.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Mcp5_PH PF12814.2 EIW69544.1 - 4.6e-43 146.0 0.2 1.5e-42 144.3 0.1 2.0 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology IMCp PF12314.3 EIW69544.1 - 4.3e-10 39.5 178.0 0.0079 16.3 28.6 6.4 1 1 4 5 5 5 5 Inner membrane complex protein PH PF00169.24 EIW69544.1 - 0.0036 17.4 0.0 0.0074 16.4 0.0 1.5 1 0 0 1 1 1 1 PH domain CUE PF02845.11 EIW69546.1 - 7e-09 35.0 0.0 1.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 CUE domain Rhomboid PF01694.17 EIW69546.1 - 1.1e-06 28.7 4.8 1.9e-06 27.9 3.3 1.4 1 0 0 1 1 1 1 Rhomboid family UBA PF00627.26 EIW69546.1 - 0.0086 15.8 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 UBA/TS-N domain DUF1751 PF08551.5 EIW69546.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) ACC_epsilon PF13822.1 EIW69546.1 - 0.02 15.2 0.1 0.064 13.6 0.1 1.8 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit adh_short PF00106.20 EIW69547.1 - 1e-20 74.2 0.0 1.6e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW69547.1 - 4.1e-06 26.5 0.0 6.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW69547.1 - 0.00038 20.3 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EIW69547.1 - 0.00075 19.2 0.6 0.002 17.8 0.4 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EIW69547.1 - 0.051 12.7 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TusA PF01206.12 EIW69547.1 - 0.13 11.9 0.0 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 Sulfurtransferase TusA zf-CCHC PF00098.18 EIW69549.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW69549.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW69549.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW69550.1 - 0.044 13.1 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Ndc1_Nup PF09531.5 EIW69552.1 - 8.5 4.6 6.1 11 4.3 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Exo_endo_phos PF03372.18 EIW69553.1 - 2.3e-12 47.4 2.1 2.4e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family NicO PF03824.11 EIW69554.1 - 3e-47 161.2 1.9 3e-47 161.2 1.4 2.4 2 1 0 2 2 2 2 High-affinity nickel-transport protein OB_NTP_bind PF07717.11 EIW69555.1 - 8.3e-26 90.0 0.0 2.5e-25 88.5 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EIW69555.1 - 2.2e-22 78.9 0.1 4.1e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIW69555.1 - 3.5e-11 42.8 0.0 1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW69555.1 - 7.8e-06 25.4 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIW69555.1 - 5e-05 23.4 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EIW69555.1 - 0.0058 15.5 0.3 0.022 13.6 0.0 2.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_14 PF13173.1 EIW69555.1 - 0.01 15.7 0.0 0.13 12.1 0.0 2.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW69555.1 - 0.012 14.7 0.1 0.063 12.3 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin ABC_tran PF00005.22 EIW69555.1 - 0.02 15.1 0.0 0.085 13.1 0.0 2.0 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.17 EIW69555.1 - 0.041 13.3 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 EIW69555.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase DUF1770 PF08589.5 EIW69556.1 - 1.5e-08 35.1 0.1 2.3e-08 34.5 0.1 1.5 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) AhpC-TSA_2 PF13911.1 EIW69557.1 - 6.1e-11 42.2 0.0 1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EIW69557.1 - 4.5e-06 26.3 0.0 6.2e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW69557.1 - 0.0054 16.2 0.0 0.0078 15.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin RhoGEF PF00621.15 EIW69558.1 - 2.5e-33 115.4 0.1 3.9e-33 114.8 0.1 1.2 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 EIW69558.1 - 3.3e-23 82.5 0.0 5.4e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EIW69558.1 - 3.6e-12 46.3 0.0 7.6e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIW69558.1 - 1.3e-06 28.5 0.0 1.5e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 PH domain Sugar_tr PF00083.19 EIW69559.1 - 1.8e-45 155.3 23.7 2.2e-45 155.0 16.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW69559.1 - 5.9e-24 84.4 38.9 3.3e-23 81.9 16.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 EIW69560.1 - 0.0041 17.0 0.0 0.007 16.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Acylphosphatase PF00708.13 EIW69561.1 - 1.1e-21 76.6 0.0 1.4e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase DUF1115 PF06544.7 EIW69561.1 - 0.038 13.6 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) Pro_isomerase PF00160.16 EIW69562.1 - 2.1e-46 157.9 0.0 4.1e-46 157.0 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EIW69562.1 - 0.00038 20.2 3.3 6.6 6.7 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat FKBP_C PF00254.23 EIW69563.1 - 6.7e-31 106.1 0.0 7.7e-31 105.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase eIF-3_zeta PF05091.7 EIW69564.1 - 4.9e-177 589.6 0.0 5.6e-177 589.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) WD40 PF00400.27 EIW69565.1 - 2.7e-15 55.5 9.1 7.8e-06 25.5 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat His_biosynth PF00977.16 EIW69566.1 - 2.7e-30 105.3 0.0 3.4e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 EIW69566.1 - 0.05 12.7 0.0 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase Sedlin_N PF04628.8 EIW69567.1 - 5.3e-22 78.0 0.0 6.9e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region BPL_LplA_LipB PF03099.14 EIW69568.1 - 2.4e-18 66.3 0.0 4.5e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 EIW69568.1 - 0.0031 17.1 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus DUF3871 PF12987.2 EIW69568.1 - 0.025 13.3 0.0 0.05 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) PTCB-BRCT PF12738.2 EIW69569.1 - 3.6e-40 135.6 5.4 1.4e-17 63.2 0.3 4.2 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EIW69569.1 - 1.9e-34 117.6 0.4 6.3e-10 39.0 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain T2SF PF00482.18 EIW69570.1 - 0.0033 17.3 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F DUF2357 PF09823.4 EIW69570.1 - 0.085 11.9 0.0 0.19 10.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2357) Abhydrolase_3 PF07859.8 EIW69571.1 - 5.6e-31 107.7 0.0 1.3e-22 80.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW69571.1 - 0.22 10.1 0.0 0.42 9.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) TPT PF03151.11 EIW69573.1 - 6.8e-12 45.2 2.2 6.8e-12 45.2 1.5 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EIW69573.1 - 5.5 7.0 19.5 0.081 12.9 8.1 2.0 2 1 0 2 2 2 0 EamA-like transporter family Adap_comp_sub PF00928.16 EIW69574.1 - 9.3e-88 293.7 0.0 1.2e-87 293.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIW69574.1 - 6.1e-06 26.0 0.9 1.1e-05 25.1 0.6 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 EIW69574.1 - 0.057 13.3 0.2 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) tRNA-synt_1 PF00133.17 EIW69575.1 - 7.2e-205 681.4 0.0 3.2e-204 679.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIW69575.1 - 6.2e-35 120.2 0.0 1.4e-34 119.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIW69575.1 - 4.2e-17 61.8 0.2 1.6e-08 33.5 0.1 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EIW69575.1 - 1.9e-11 43.6 0.0 4.4e-07 29.3 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EIW69575.1 - 0.021 13.6 0.0 0.064 12.0 0.0 1.8 1 0 0 1 1 1 0 tRNA synthetases class I (R) HD_3 PF13023.1 EIW69575.1 - 0.043 13.5 0.5 0.11 12.2 0.3 1.6 1 0 0 1 1 1 0 HD domain tRNA-synt_1e PF01406.14 EIW69575.1 - 0.05 12.7 0.0 3.7 6.5 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Ribonuc_2-5A PF06479.7 EIW69577.1 - 3e-44 149.9 0.0 4.7e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EIW69577.1 - 1.1e-41 142.7 0.0 1.6e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69577.1 - 2.2e-22 79.3 0.0 3.7e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.1 EIW69577.1 - 0.00043 19.8 0.0 0.00093 18.7 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 EIW69577.1 - 0.013 14.6 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ PF01011.16 EIW69577.1 - 0.03 13.8 0.0 4.3 7.0 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat APH PF01636.18 EIW69577.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family CPL PF08144.6 EIW69578.1 - 4.3e-22 78.5 0.1 1.3e-20 73.8 0.0 2.7 3 0 0 3 3 3 1 CPL (NUC119) domain DUF3516 PF12029.3 EIW69578.1 - 0.028 13.2 0.0 0.053 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) nec1 PF10379.4 EIW69582.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Virulence protein nec1 DUF4625 PF15418.1 EIW69582.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Fungal_trans PF04082.13 EIW69590.1 - 5.9e-12 45.0 0.0 1.2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW69590.1 - 7.4e-07 28.9 10.2 1.4e-06 28.0 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 EIW69590.1 - 0.21 11.2 2.4 0.5 10.1 1.6 1.6 1 0 0 1 1 1 0 Serglycin Metallophos PF00149.23 EIW69591.1 - 1.3e-39 135.7 0.1 1.6e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TRAPP PF04051.11 EIW69592.1 - 2.3e-35 121.3 0.0 2.8e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Acyl-CoA_dh_1 PF00441.19 EIW69593.1 - 1.2e-28 100.1 1.7 1.7e-28 99.5 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIW69593.1 - 2.3e-18 65.4 2.1 4.2e-18 64.6 1.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EIW69593.1 - 3e-12 46.1 0.0 7.5e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EIW69593.1 - 4.6e-08 33.6 0.0 1.3e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIW69593.1 - 0.0021 18.3 0.2 0.0042 17.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_transf_18 PF15024.1 EIW69596.1 - 0.0024 16.3 0.0 0.0033 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 Glyco_transf_6 PF03414.8 EIW69596.1 - 0.039 12.4 0.2 4.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 6 zf-C2HC5 PF06221.8 EIW69597.1 - 7.8e-13 47.9 6.8 1.3e-12 47.2 4.7 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type PWI PF01480.12 EIW69597.1 - 3.6e-05 23.7 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 PWI domain Glyco_transf_34 PF05637.7 EIW69598.1 - 9.7e-05 21.9 0.4 0.002 17.6 0.0 2.5 2 1 1 3 3 3 1 galactosyl transferase GMA12/MNN10 family DUF4411 PF14367.1 EIW69598.1 - 0.12 12.0 2.9 8.1 6.1 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) Rab5ip PF07019.7 EIW69599.1 - 1.3e-07 31.5 8.8 9e-07 28.9 5.8 2.0 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF3899 PF13038.1 EIW69606.1 - 0.098 12.8 0.5 0.23 11.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF3498 PF12004.3 EIW69607.1 - 0.04 13.0 0.6 0.057 12.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) CENP-B_dimeris PF09026.5 EIW69607.1 - 0.57 10.4 8.2 1.1 9.5 5.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 EIW69607.1 - 3.4 6.6 6.1 4.7 6.1 4.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-CCHC PF00098.18 EIW69608.1 - 0.0002 21.1 1.8 0.00032 20.4 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIW69608.1 - 0.051 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW69608.1 - 0.22 11.7 8.3 0.096 12.9 3.8 1.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain zf-CCHC_5 PF14787.1 EIW69608.1 - 1.1 8.8 8.7 0.094 12.2 2.3 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DEAD PF00270.24 EIW69610.1 - 4.4e-47 159.7 0.0 8.4e-46 155.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW69610.1 - 3.2e-24 84.5 0.0 7.1e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIW69610.1 - 0.00071 18.4 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-UBR PF02207.15 EIW69611.1 - 1.5e-11 43.7 10.8 1.5e-11 43.7 7.5 2.6 1 1 1 2 2 2 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 EIW69611.1 - 2.5e-05 23.8 2.6 2.5e-05 23.8 1.8 3.2 3 1 1 4 4 4 1 PHD-finger Agglutinin PF07468.6 EIW69611.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Agglutinin DUF536 PF04394.9 EIW69611.1 - 0.25 11.0 2.1 0.67 9.7 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF536 DUF3716 PF12511.3 EIW69612.1 - 0.1 12.2 5.7 0.18 11.4 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Transket_pyr PF02779.19 EIW69613.1 - 1.3e-63 213.7 0.0 2.1e-63 213.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EIW69613.1 - 8.5e-57 192.1 0.0 1.2e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component FAD-oxidase_C PF02913.14 EIW69614.1 - 8.2e-54 182.5 0.0 1.1e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIW69614.1 - 3.5e-35 120.5 0.2 7.4e-35 119.4 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain EpuA PF11772.3 EIW69614.1 - 0.1 12.0 0.6 0.21 11.0 0.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta A1_Propeptide PF07966.7 EIW69614.1 - 0.13 12.0 0.2 0.28 11.0 0.2 1.6 1 0 0 1 1 1 0 A1 Propeptide Hexapep PF00132.19 EIW69615.1 - 1.1e-11 43.7 13.3 0.003 16.9 0.3 3.7 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIW69615.1 - 1.3e-06 27.8 9.5 5.5e-05 22.6 4.8 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Syntaxin_2 PF14523.1 EIW69616.1 - 6.9e-25 87.0 0.4 2.7e-23 81.9 0.0 2.3 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EIW69616.1 - 1.7e-18 66.0 8.4 9.6e-17 60.4 0.6 2.9 3 0 0 3 3 3 2 SNARE domain Syntaxin PF00804.20 EIW69616.1 - 0.0029 17.7 3.1 0.0052 16.9 0.2 2.5 1 1 1 2 2 2 1 Syntaxin MCPsignal PF00015.16 EIW69616.1 - 0.0076 15.8 0.3 0.0076 15.8 0.2 2.5 3 0 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 EIW69616.1 - 0.014 15.0 1.9 0.015 14.8 0.2 2.0 2 0 0 2 2 1 0 Synaptobrevin Abhydrolase_9_N PF15420.1 EIW69616.1 - 0.015 15.0 1.3 0.027 14.2 0.9 1.4 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF912 PF06024.7 EIW69616.1 - 0.021 14.8 0.9 0.039 13.9 0.1 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ODV-E18 PF10717.4 EIW69616.1 - 0.055 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Cortex-I_coil PF09304.5 EIW69616.1 - 0.058 13.4 3.6 0.28 11.2 0.7 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil Herpes_US9 PF06072.6 EIW69616.1 - 0.099 12.4 1.4 0.25 11.1 1.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Med11 PF10280.4 EIW69616.1 - 0.14 12.2 1.3 0.48 10.4 0.0 2.3 2 1 0 2 2 2 0 Mediator complex protein PIG-Y PF15159.1 EIW69616.1 - 0.22 11.7 8.2 0.41 10.8 5.7 1.4 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Rifin_STEVOR PF02009.11 EIW69616.1 - 0.39 10.3 3.0 0.66 9.5 2.1 1.6 1 1 0 1 1 1 0 Rifin/stevor family SlyX PF04102.7 EIW69616.1 - 1.1 9.7 4.6 1.9 8.9 0.0 3.0 3 2 0 3 3 3 0 SlyX Actin PF00022.14 EIW69617.1 - 1e-19 70.2 0.0 7e-19 67.5 0.0 2.2 2 1 0 2 2 2 1 Actin MreB_Mbl PF06723.8 EIW69617.1 - 0.00019 20.1 0.0 0.0078 14.8 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.15 EIW69617.1 - 0.027 13.7 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF3808 PF10300.4 EIW69618.1 - 3.5e-75 253.3 0.0 6e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 EIW69618.1 - 0.00028 20.5 7.2 0.046 13.6 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW69618.1 - 0.00043 19.8 0.7 0.01 15.5 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW69618.1 - 0.00051 19.9 1.0 0.088 12.7 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIW69618.1 - 0.009 16.6 0.3 7.2 7.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW69618.1 - 0.019 14.5 2.3 0.17 11.5 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW69618.1 - 0.058 13.8 0.1 1.6 9.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIW69618.1 - 0.094 12.3 5.7 0.27 10.9 0.0 3.7 3 1 1 4 4 4 0 TPR repeat RPN7 PF10602.4 EIW69618.1 - 0.1 11.9 1.2 0.26 10.6 0.2 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_7 PF13176.1 EIW69618.1 - 1.1 9.1 0.0 1.1 9.1 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Orn_Arg_deC_N PF02784.11 EIW69619.1 - 7e-64 215.4 0.0 9e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EIW69619.1 - 5.9e-29 100.1 0.0 1.1e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Oest_recep PF02159.10 EIW69619.1 - 0.29 11.2 1.2 0.64 10.1 0.9 1.5 1 0 0 1 1 1 0 Oestrogen receptor HMA PF00403.21 EIW69621.1 - 3.2e-12 46.3 0.0 1.1e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Heavy-metal-associated domain Metallophos PF00149.23 EIW69622.1 - 3.1e-44 150.7 0.1 3.8e-44 150.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans_2 PF11951.3 EIW69623.1 - 2.4e-44 151.4 0.0 4.6e-44 150.5 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW69623.1 - 2.3e-06 27.3 12.6 3.8e-06 26.6 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adeno_E1B_55K_N PF04623.7 EIW69624.1 - 2.4 8.7 6.5 5 7.6 4.5 1.5 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus DUF3759 PF12585.3 EIW69625.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) RRM_2 PF04059.7 EIW69626.1 - 9.3e-29 99.2 0.3 2e-28 98.2 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EIW69626.1 - 7.9e-09 35.0 2.7 1.1e-05 24.9 0.0 3.6 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW69626.1 - 0.00032 20.5 1.1 0.91 9.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW69626.1 - 0.028 14.2 0.1 21 5.0 0.0 3.3 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP72 PF08492.7 EIW69627.1 - 1.5e-10 41.3 1.6 1.5e-10 41.3 1.1 1.9 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_11 PF13414.1 EIW69627.1 - 1.7e-07 30.7 0.4 0.13 11.8 0.0 3.2 3 0 0 3 3 3 2 TPR repeat Apc3 PF12895.2 EIW69627.1 - 6.3e-07 29.4 1.6 5e-06 26.5 0.9 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIW69627.1 - 0.00026 21.5 0.1 8.1 7.2 0.9 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW69627.1 - 0.00047 20.5 0.1 4.9 8.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIW69627.1 - 0.00084 19.0 5.9 1 9.4 0.4 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW69627.1 - 0.0012 19.1 0.2 0.29 11.5 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW69627.1 - 0.0067 16.3 1.7 0.095 12.6 0.0 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIW69627.1 - 0.0087 15.1 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW69627.1 - 0.03 14.1 0.0 3.4 7.7 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW69627.1 - 0.035 13.7 1.8 1.5 8.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIW69627.1 - 0.041 13.7 1.1 0.54 10.1 1.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW69627.1 - 0.059 13.8 1.7 18 6.0 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 EIW69628.1 - 4.2e-39 134.2 64.6 9.3e-28 96.9 16.4 3.0 1 1 1 3 3 3 3 Major Facilitator Superfamily Myb_DNA-bind_6 PF13921.1 EIW69631.1 - 3.2e-07 30.3 0.6 0.0054 16.8 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIW69631.1 - 0.00039 20.3 1.5 0.2 11.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.20 EIW69633.1 - 1.2e-23 82.5 2.5 1.8e-23 82.0 1.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EIW69633.1 - 2.2e-22 79.0 0.0 3.6e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EIW69633.1 - 0.00087 18.6 0.1 0.084 12.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family RmlD_sub_bind PF04321.12 EIW69634.1 - 6.2e-42 143.4 0.0 1.7e-41 142.0 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EIW69634.1 - 4.4e-21 75.4 0.1 1.1e-20 74.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW69634.1 - 1e-10 41.9 0.1 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW69634.1 - 2e-09 36.7 0.0 5.6e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EIW69634.1 - 0.0026 16.5 0.1 0.085 11.5 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EIW69634.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EIW69634.1 - 0.012 15.5 0.1 0.049 13.5 0.0 2.1 3 0 0 3 3 3 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIW69634.1 - 0.061 12.2 0.0 3.4 6.4 0.0 2.7 2 1 0 3 3 3 0 Polysaccharide biosynthesis protein Nol1_Nop2_Fmu PF01189.12 EIW69635.1 - 9.3e-101 336.9 0.0 1.2e-100 336.5 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EIW69635.1 - 0.00089 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EIW69635.1 - 0.0029 17.2 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EIW69635.1 - 0.01 16.4 0.2 0.044 14.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 EIW69635.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 EIW69635.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 EIW69635.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) EPSP_synthase PF00275.15 EIW69636.1 - 5e-119 397.4 0.1 7.3e-119 396.9 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EIW69636.1 - 7.4e-98 326.6 0.0 2e-96 321.9 0.0 2.2 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EIW69636.1 - 3.1e-53 180.7 0.0 4.9e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EIW69636.1 - 7.3e-33 113.6 0.0 5.7e-32 110.7 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EIW69636.1 - 1.6e-22 79.3 0.0 4.7e-22 77.8 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EIW69636.1 - 3.1e-11 43.5 0.0 7.1e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EIW69636.1 - 5.9e-11 42.1 0.4 1.8e-10 40.5 0.1 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EIW69636.1 - 0.0063 17.3 0.0 0.015 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NUDIX PF00293.23 EIW69637.1 - 2.5e-18 66.0 0.2 4.3e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain BRCT_assoc PF12820.2 EIW69637.1 - 0.13 12.0 0.8 0.21 11.3 0.6 1.3 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT HIG_1_N PF04588.8 EIW69639.1 - 5.5e-20 70.8 3.1 7.6e-20 70.4 2.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2909 PF11137.3 EIW69639.1 - 0.002 17.8 0.5 0.003 17.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2909) SAC3_GANP PF03399.11 EIW69640.1 - 6.5e-25 87.8 0.0 9.4e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EIW69640.1 - 3.3e-21 75.5 0.0 5.6e-21 74.8 0.0 1.4 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 NTF2 PF02136.15 EIW69641.1 - 1.1e-25 90.2 0.0 1.9e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_5 PF13893.1 EIW69641.1 - 3e-09 36.5 0.1 9.2e-09 35.0 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW69641.1 - 5.5e-08 32.6 0.1 1.6e-07 31.1 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW69641.1 - 1.7e-06 27.5 0.4 3.4e-06 26.6 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIW69641.1 - 0.092 12.5 0.2 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif Methyltransf_10 PF05971.7 EIW69642.1 - 5.1e-58 196.5 0.0 6.5e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EIW69642.1 - 5.5e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EIW69642.1 - 3.6e-06 26.6 0.0 6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 EIW69642.1 - 9.8e-06 25.0 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EIW69642.1 - 1.4e-05 24.6 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW69642.1 - 0.00091 19.7 0.0 0.0016 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIW69642.1 - 0.0024 17.0 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 EIW69642.1 - 0.04 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.7 EIW69642.1 - 0.085 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Tyr_Deacylase PF02580.11 EIW69643.1 - 4.7e-37 127.1 0.0 5.4e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Bestrophin PF01062.16 EIW69644.1 - 2.7e-16 59.3 0.0 8.9e-10 37.9 0.0 2.3 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Corona_nucleoca PF00937.13 EIW69644.1 - 0.34 9.8 2.7 0.5 9.2 1.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Rft-1 PF04506.8 EIW69645.1 - 4.7e-50 170.4 7.2 6.1e-48 163.5 5.0 2.7 1 1 0 1 1 1 1 Rft protein DUF2269 PF10027.4 EIW69645.1 - 0.021 14.6 2.6 0.21 11.3 0.1 3.0 2 1 1 3 3 3 0 Predicted integral membrane protein (DUF2269) ATP_bind_1 PF03029.12 EIW69646.1 - 9.6e-76 254.4 0.0 1.2e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EIW69646.1 - 7.4e-05 22.2 0.0 0.0002 20.8 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EIW69646.1 - 0.00099 17.9 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_19 PF13245.1 EIW69646.1 - 0.0054 16.4 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIW69646.1 - 0.034 13.7 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EIW69646.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA PF00004.24 EIW69646.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 EIW69646.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EIW69646.1 - 0.13 12.1 0.0 0.4 10.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIW69646.1 - 0.14 13.0 8.4 0.19 12.5 2.1 3.1 2 2 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIW69646.1 - 6.5 7.0 5.8 1.1 9.5 0.2 2.5 3 0 0 3 3 3 0 AAA domain GATase_4 PF13230.1 EIW69647.1 - 3.6e-18 65.2 0.1 2.6e-16 59.1 0.1 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIW69647.1 - 1.6e-07 31.3 0.0 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EIW69647.1 - 8.9e-07 27.9 0.0 2.7e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II SNase PF00565.12 EIW69648.1 - 4.8e-50 168.3 0.0 4.5e-17 62.2 0.0 6.8 6 1 0 6 6 6 6 Staphylococcal nuclease homologue TUDOR PF00567.19 EIW69648.1 - 3.3e-23 81.8 0.0 6.3e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Peptidase_S24 PF00717.18 EIW69648.1 - 0.017 14.7 0.0 2.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Peptidase S24-like SMN PF06003.7 EIW69648.1 - 0.018 14.1 0.0 0.052 12.6 0.0 1.7 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) DUF3123 PF11321.3 EIW69648.1 - 0.029 14.6 0.2 0.089 13.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) 2OG-FeII_Oxy PF03171.15 EIW69649.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EIW69650.1 - 1.3e-49 168.7 0.1 3.5e-38 131.2 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69650.1 - 1.7e-27 96.1 0.0 4.4e-27 94.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW69650.1 - 3.1e-08 32.9 0.0 5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW69650.1 - 2.2e-05 23.6 0.1 2.2e-05 23.6 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW69650.1 - 0.054 13.2 0.2 0.27 10.9 0.1 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family DPBB_1 PF03330.13 EIW69651.1 - 7.7e-05 22.6 1.0 0.00034 20.5 0.0 2.4 1 1 1 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4175 PF13779.1 EIW69652.1 - 7.9 4.0 14.4 12 3.3 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mid1 PF12929.2 EIW69653.1 - 2.7e-53 181.2 2.5 4.7e-50 170.5 1.8 2.4 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Kinesin PF00225.18 EIW69654.1 - 1e-54 185.4 0.0 1.5e-43 148.7 0.0 2.3 1 1 1 2 2 2 2 Kinesin motor domain Beta-lactamase PF00144.19 EIW69654.1 - 1.2e-35 123.1 0.0 2e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF1021 PF06257.6 EIW69654.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) AAA_22 PF13401.1 EIW69654.1 - 0.13 12.3 0.0 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATG16 PF08614.6 EIW69655.1 - 0.0036 17.1 13.1 0.0056 16.5 9.1 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) UPF0020 PF01170.13 EIW69655.1 - 0.029 13.9 1.4 0.048 13.2 1.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Laminin_I PF06008.9 EIW69655.1 - 0.12 11.6 17.0 0.19 11.0 11.8 1.2 1 0 0 1 1 1 0 Laminin Domain I SPX PF03105.14 EIW69655.1 - 0.44 10.2 4.4 0.65 9.7 3.0 1.2 1 0 0 1 1 1 0 SPX domain APG6 PF04111.7 EIW69655.1 - 0.51 9.3 17.8 0.63 9.0 5.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Pox_A_type_inc PF04508.7 EIW69655.1 - 0.64 9.9 5.2 4.1 7.4 0.6 3.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Imm46 PF15585.1 EIW69655.1 - 0.76 9.8 4.0 0.86 9.6 1.7 1.8 1 1 0 2 2 2 0 Immunity protein 46 Lge1 PF11488.3 EIW69655.1 - 1.5 9.1 10.4 4.2 7.6 1.3 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 V_ATPase_I PF01496.14 EIW69655.1 - 1.7 6.3 6.9 2.5 5.8 4.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.3 EIW69655.1 - 4.2 7.1 22.2 9 6.0 7.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF724 PF05266.9 EIW69655.1 - 5.3 6.6 14.7 0.14 11.7 3.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Tup_N PF08581.5 EIW69655.1 - 5.4 7.2 14.4 0.56 10.4 5.1 2.5 1 1 1 2 2 2 0 Tup N-terminal DivIC PF04977.10 EIW69655.1 - 6.6 6.3 22.7 0.17 11.4 1.8 4.1 3 1 1 4 4 4 0 Septum formation initiator DUF2664 PF10867.3 EIW69655.1 - 7.6 7.2 14.6 0.29 11.7 2.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) TPR_MLP1_2 PF07926.7 EIW69655.1 - 8.5 6.1 21.5 2.3 7.9 7.2 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein RFPL3_antisense PF10489.4 EIW69656.1 - 0.019 14.7 0.7 4.3 7.1 0.2 2.2 2 0 0 2 2 2 0 Ret finger protein-like 3 antisense PBP1_TM PF14812.1 EIW69656.1 - 0.96 9.7 4.6 0.43 10.9 1.6 1.7 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3554 PF12074.3 EIW69657.1 - 3.5e-49 168.0 6.2 3.7e-48 164.7 0.4 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) HEAT PF02985.17 EIW69657.1 - 7.8e-39 128.2 29.2 0.13 12.4 0.0 22.5 24 0 0 24 24 23 11 HEAT repeat HEAT_2 PF13646.1 EIW69657.1 - 1.9e-38 130.6 46.4 1e-07 32.1 0.0 16.7 14 3 5 19 19 17 8 HEAT repeats HEAT_EZ PF13513.1 EIW69657.1 - 2e-36 123.5 35.4 0.0005 20.4 0.0 20.5 17 4 6 23 23 22 9 HEAT-like repeat Adaptin_N PF01602.15 EIW69657.1 - 7.5e-20 70.7 0.0 0.00097 17.5 0.0 7.9 7 1 1 8 8 8 5 Adaptin N terminal region CLASP_N PF12348.3 EIW69657.1 - 2e-15 56.7 0.0 4e-05 23.0 0.0 7.3 3 1 2 6 6 6 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 EIW69657.1 - 9.9e-13 48.2 0.0 0.032 14.5 0.0 7.6 6 2 2 8 8 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EIW69657.1 - 0.0001 22.2 0.0 25 4.6 0.0 6.8 6 1 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EIW69657.1 - 0.001 19.0 7.6 1.7 8.5 0.0 6.6 6 2 1 7 7 7 1 Parkin co-regulated protein Arm PF00514.18 EIW69657.1 - 0.0014 18.3 1.1 6.5 6.7 0.0 5.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 EIW69657.1 - 0.0024 17.8 0.7 1.2 9.1 0.1 4.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Herpes_ICP4_N PF03584.10 EIW69657.1 - 0.018 14.5 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region DUF2669 PF10876.3 EIW69657.1 - 0.051 13.2 0.0 3.1 7.5 0.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2669) Ribosomal_L18e PF00828.14 EIW69658.1 - 5.8e-31 107.5 0.4 8e-31 107.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L16 PF00252.13 EIW69659.1 - 9.5e-33 112.7 0.1 1.2e-32 112.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CTP_transf_2 PF01467.21 EIW69660.1 - 1.3e-07 31.7 0.0 4.5e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase RrnaAD PF00398.15 EIW69661.1 - 1.1e-10 40.9 0.0 0.00047 19.2 0.0 3.4 2 2 0 2 2 2 2 Ribosomal RNA adenine dimethylase RNase_P_p30 PF01876.11 EIW69662.1 - 1.3e-23 82.8 0.0 2.1e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 Peptidase_M3 PF01432.15 EIW69663.1 - 1.4e-119 400.2 0.0 1.8e-119 399.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Rhabdo_NV PF02484.10 EIW69663.1 - 0.09 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein API5 PF05918.6 EIW69663.1 - 0.19 10.2 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CCDC155 PF14662.1 EIW69664.1 - 0.0016 18.0 2.5 0.0031 17.1 1.8 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 bZIP_1 PF00170.16 EIW69664.1 - 0.021 14.7 2.0 0.043 13.7 1.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor FtsL PF04999.8 EIW69664.1 - 0.15 11.7 0.8 0.43 10.3 0.6 1.8 1 0 0 1 1 1 0 Cell division protein FtsL RRM_1 PF00076.17 EIW69665.1 - 6.6e-20 70.5 0.0 1.9e-18 65.8 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW69665.1 - 2.7e-14 52.9 0.0 2.1e-11 43.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW69665.1 - 3e-06 26.9 0.0 8.9e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_90 PF05686.7 EIW69667.1 - 1.4e-20 73.4 0.2 3.9e-20 71.9 0.2 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 MerR-DNA-bind PF09278.6 EIW69667.1 - 0.0014 19.0 0.0 0.18 12.2 0.0 2.6 2 0 0 2 2 2 2 MerR, DNA binding Cellulase PF00150.13 EIW69668.1 - 0.00037 19.8 0.0 3.1 6.8 0.0 3.2 3 0 0 3 3 3 3 Cellulase (glycosyl hydrolase family 5) DUF2237 PF09996.4 EIW69669.1 - 1.7e-32 111.3 0.0 2.3e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Porin_OmpG PF09381.5 EIW69670.1 - 0.92 8.5 0.0 1.4 7.9 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) DUF1515 PF07439.6 EIW69670.1 - 2.3 8.0 7.6 3.4 7.5 1.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) Pkinase PF00069.20 EIW69671.1 - 4.2e-74 248.9 0.0 5e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69671.1 - 2.4e-38 131.7 0.0 3.7e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW69671.1 - 7.9e-05 22.5 0.0 0.0015 18.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW69671.1 - 0.00014 20.8 0.0 0.00026 20.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW69671.1 - 0.00022 20.3 0.0 0.00033 19.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIW69671.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EIW69671.1 - 0.0037 16.6 0.1 0.0098 15.2 0.1 1.6 1 1 0 1 1 1 1 RIO1 family UPF0262 PF06793.7 EIW69671.1 - 0.11 12.2 0.1 0.63 9.7 0.0 2.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0262) Chromo PF00385.19 EIW69672.1 - 1.1e-06 28.2 0.2 2.1e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EIW69672.1 - 2.3e-05 23.9 2.8 4.9e-05 22.9 1.9 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EIW69672.1 - 3.4e-05 23.0 2.6 7.1e-05 22.0 1.8 1.5 1 0 0 1 1 1 1 PHD-finger DUF3439 PF11921.3 EIW69672.1 - 0.91 9.2 6.4 0.16 11.7 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DASH_Spc34 PF08657.5 EIW69672.1 - 6.2 6.3 11.7 0.12 11.9 1.6 2.4 2 0 0 2 2 2 0 DASH complex subunit Spc34 Dicty_REP PF05086.7 EIW69672.1 - 8.8 3.9 8.7 0.45 8.2 1.9 1.7 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Spb1_C PF07780.7 EIW69673.1 - 3.3e-66 222.8 30.4 3.3e-66 222.8 21.1 3.8 3 2 2 5 5 5 1 Spb1 C-terminal domain FtsJ PF01728.14 EIW69673.1 - 2.9e-52 177.2 0.0 6.1e-52 176.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EIW69673.1 - 7.9e-46 155.4 3.6 7.9e-46 155.4 2.5 5.5 5 1 0 5 5 5 1 Domain of unknown function (DUF3381) Phage_Coat_A PF05357.8 EIW69673.1 - 0.038 13.5 0.2 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Phage Coat Protein A RasGAP_C PF03836.10 EIW69674.1 - 8.1e-36 122.8 0.5 8.1e-36 122.8 0.3 2.0 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.22 EIW69674.1 - 2.5e-25 85.6 61.1 0.0066 15.9 0.1 13.3 13 0 0 13 13 13 9 IQ calmodulin-binding motif RasGAP PF00616.14 EIW69674.1 - 2.7e-22 79.4 0.0 1.4e-21 77.0 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 EIW69674.1 - 2.5e-09 37.1 0.0 6.2e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain Sipho_Gp157 PF05565.6 EIW69674.1 - 0.011 15.3 5.8 0.17 11.4 0.2 2.9 2 0 0 2 2 2 0 Siphovirus Gp157 DivIC PF04977.10 EIW69674.1 - 0.18 11.3 7.9 4.4 6.8 0.2 3.1 2 0 0 2 2 2 0 Septum formation initiator PQ-loop PF04193.9 EIW69675.1 - 6.1e-26 89.7 12.0 6.2e-15 54.5 1.0 3.2 3 1 1 4 4 4 2 PQ loop repeat Mito_carr PF00153.22 EIW69676.1 - 4e-59 196.3 1.6 2.5e-22 78.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.1 EIW69676.1 - 0.1 12.3 0.0 0.73 9.5 0.0 2.2 2 0 0 2 2 2 0 PrcB C-terminal Foie-gras_1 PF11817.3 EIW69677.1 - 2.5e-40 138.5 0.0 1.4e-39 136.1 0.0 2.1 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.7 EIW69677.1 - 4.2e-25 88.1 9.0 2.9e-23 82.0 6.2 2.1 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi PCMT PF01135.14 EIW69678.1 - 5.7e-60 202.4 0.0 6.7e-60 202.2 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EIW69678.1 - 7.4e-11 42.6 0.0 1.4e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW69678.1 - 3.6e-09 36.3 0.1 6.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW69678.1 - 1.3e-07 31.1 0.0 2.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EIW69678.1 - 1.5e-06 28.5 0.0 2.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW69678.1 - 9.2e-06 25.6 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW69678.1 - 5.4e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EIW69678.1 - 0.00014 21.5 0.0 0.00027 20.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIW69678.1 - 0.00014 21.1 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EIW69678.1 - 0.0003 21.1 0.0 0.00069 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW69678.1 - 0.0024 18.3 0.0 0.0082 16.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 EIW69678.1 - 0.0047 15.9 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 EIW69678.1 - 0.0078 15.4 0.6 0.012 14.8 0.4 1.2 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 EIW69678.1 - 0.035 13.2 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EIW69678.1 - 0.059 12.4 0.0 0.084 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Rgp1 PF08737.5 EIW69679.1 - 2.8e-65 221.0 0.1 1.8e-64 218.3 0.0 2.2 2 1 0 2 2 2 1 Rgp1 MOZ_SAS PF01853.13 EIW69680.1 - 9.3e-89 295.6 1.6 1.3e-88 295.1 1.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EIW69680.1 - 5.4e-21 74.0 0.0 1.2e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_Mga PF08280.6 EIW69680.1 - 0.00099 18.8 0.6 0.0024 17.5 0.4 1.6 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Shadoo PF14999.1 EIW69680.1 - 0.0022 17.8 1.8 0.0037 17.1 1.2 1.3 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective HTH_11 PF08279.7 EIW69680.1 - 0.0077 15.8 0.1 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 HTH domain Acetyltransf_1 PF00583.19 EIW69680.1 - 0.0087 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ebola_NP PF05505.7 EIW69680.1 - 0.19 9.7 4.3 0.25 9.3 3.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein SUR7 PF06687.7 EIW69681.1 - 2.3e-07 30.5 26.5 3.5e-05 23.4 18.3 2.0 1 1 0 1 1 1 1 SUR7/PalI family Claudin_3 PF06653.6 EIW69681.1 - 0.56 9.9 15.9 2.1 8.0 11.1 1.7 1 1 0 1 1 1 0 Tight junction protein, Claudin-like zf-DHHC PF01529.15 EIW69681.1 - 1.5 8.2 7.1 0.42 9.9 0.2 2.2 2 1 0 2 2 2 0 DHHC palmitoyltransferase RNA_pol_L_2 PF13656.1 EIW69684.1 - 4.5e-25 86.8 0.1 5.8e-25 86.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EIW69684.1 - 3.7e-11 41.9 0.0 5e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Glyco_transf_20 PF00982.16 EIW69685.1 - 3e-136 454.6 0.0 4.3e-105 351.9 0.0 2.4 3 0 0 3 3 3 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIW69685.1 - 4.3e-73 245.1 0.0 9.6e-73 243.9 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase Ank_4 PF13637.1 EIW69686.1 - 1.5e-11 44.4 0.0 7.6e-07 29.4 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIW69686.1 - 2.4e-11 43.8 0.0 1.7e-10 41.0 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIW69686.1 - 2.4e-09 37.1 0.1 3.3e-08 33.5 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW69686.1 - 2.4e-08 33.4 0.1 4.2e-05 23.3 0.1 3.8 3 1 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 EIW69686.1 - 6.6e-08 31.9 0.5 5.6e-05 22.7 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat F-box-like PF12937.2 EIW69687.1 - 0.34 10.6 2.9 0.86 9.3 2.0 1.8 1 1 0 1 1 1 0 F-box-like Mito_carr PF00153.22 EIW69688.1 - 7.6e-53 176.2 3.1 1.9e-18 65.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.1 EIW69688.1 - 0.093 12.4 0.0 0.76 9.5 0.0 2.1 2 0 0 2 2 2 0 PrcB C-terminal HMD PF03201.11 EIW69688.1 - 0.12 12.2 0.0 2.6 8.0 0.0 2.6 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PHB_acc_N PF07879.6 EIW69689.1 - 2.9 7.6 9.3 5.5 6.7 0.1 3.3 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain RINT1_TIP1 PF04437.8 EIW69690.1 - 2.2e-74 250.8 0.0 1.5e-73 248.1 0.0 1.9 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Chromo PF00385.19 EIW69691.1 - 2.4e-07 30.3 0.5 6.3e-07 28.9 0.2 1.8 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EIW69691.1 - 7.1e-05 22.4 1.7 0.0002 20.9 1.2 1.8 1 0 0 1 1 1 1 PHD-finger TFIIE_alpha PF02002.12 EIW69691.1 - 0.098 12.1 0.2 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit PHD_2 PF13831.1 EIW69691.1 - 4.7 6.6 6.3 0.48 9.7 1.1 1.9 2 0 0 2 2 2 0 PHD-finger Acyltransferase PF01553.16 EIW69692.1 - 1.1e-20 73.4 0.0 1.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase zf-rbx1 PF12678.2 EIW69693.1 - 1.4e-34 117.9 13.3 1.7e-34 117.7 9.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIW69693.1 - 7.5e-17 60.9 10.3 9e-17 60.7 7.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EIW69693.1 - 3e-06 26.9 13.1 1.7e-05 24.5 9.0 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIW69693.1 - 0.0037 16.8 12.7 0.043 13.4 8.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW69693.1 - 0.017 14.8 9.8 0.68 9.6 6.9 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW69693.1 - 0.084 12.9 13.5 2.1 8.4 9.4 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EIW69693.1 - 0.2 11.6 8.1 5.4 7.0 6.1 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EIW69693.1 - 0.2 11.6 9.1 0.32 11.0 6.3 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIW69693.1 - 0.77 9.9 11.0 14 5.9 7.1 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 EIW69693.1 - 3.5 7.4 12.9 70 3.2 9.0 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EIW69693.1 - 5 6.9 8.8 84 3.0 6.1 2.2 1 1 0 1 1 1 0 RING-type zinc-finger Mito_carr PF00153.22 EIW69694.1 - 1.2e-41 140.2 7.5 3.2e-15 55.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_C PF12806.2 EIW69694.1 - 0.036 13.9 0.1 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Spore_YtrH PF14034.1 EIW69694.1 - 0.043 13.7 0.3 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 Sporulation protein YtrH Suf PF05843.9 EIW69695.1 - 3.9e-82 276.1 0.0 3.1e-79 266.6 0.0 2.7 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EIW69695.1 - 1.3e-05 25.4 10.4 0.017 15.7 0.0 6.0 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW69695.1 - 0.00011 22.5 0.7 1.6 9.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW69695.1 - 0.025 15.2 13.2 2.3 8.9 0.0 4.5 3 1 0 4 4 4 0 Tetratricopeptide repeat Chromo PF00385.19 EIW69696.1 - 2.6e-08 33.4 1.0 4.6e-08 32.6 0.7 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EIW69696.1 - 2.2e-05 24.0 4.5 4.4e-05 23.0 3.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EIW69696.1 - 8.5e-05 21.7 4.4 0.00016 20.9 3.1 1.4 1 0 0 1 1 1 1 PHD-finger DUF2296 PF10058.4 EIW69696.1 - 0.084 12.6 0.3 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) zf-CCHC PF00098.18 EIW69697.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW69697.1 - 0.35 11.1 8.0 0.092 12.9 3.4 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW69697.1 - 0.63 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) PH_9 PF15410.1 EIW69698.1 - 5.2e-09 36.2 0.0 0.00034 20.7 0.1 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.24 EIW69698.1 - 3.8e-07 30.2 0.0 2e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 EIW69698.1 - 0.0012 19.0 0.0 1.6 8.9 0.0 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain Abhydrolase_5 PF12695.2 EIW69700.1 - 1.3e-06 28.2 0.0 2.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family UCH PF00443.24 EIW69701.1 - 4.1e-07 29.3 0.0 8.9e-07 28.2 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW69701.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.11 EIW69702.1 - 1.3e-29 103.0 24.3 1.3e-29 103.0 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIW69702.1 - 0.028 14.2 0.3 0.028 14.2 0.2 3.2 3 0 0 3 3 3 0 MFS_1 like family DUF4341 PF14241.1 EIW69702.1 - 0.054 13.2 6.9 2.5 7.8 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4341) PQ-loop PF04193.9 EIW69703.1 - 6.9e-20 70.3 8.2 1.1e-11 44.1 0.8 2.9 2 1 1 3 3 3 2 PQ loop repeat PQ-loop PF04193.9 EIW69704.1 - 5.4e-17 61.0 4.9 4.7e-08 32.4 0.2 2.8 2 1 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EIW69704.1 - 1 9.2 6.7 9.3 6.2 0.1 2.7 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.9 EIW69705.1 - 1.1e-28 98.5 15.3 1.1e-14 53.7 1.6 2.8 3 0 0 3 3 3 2 PQ loop repeat Cyd_oper_YbgE PF09600.5 EIW69705.1 - 2 8.6 12.9 3.1 8.0 1.4 2.8 3 0 0 3 3 3 0 Cyd operon protein YbgE (Cyd_oper_YbgE) MtN3_slv PF03083.11 EIW69705.1 - 3.7 7.4 9.8 13 5.7 2.7 3.0 2 2 1 3 3 3 0 Sugar efflux transporter for intercellular exchange ER_lumen_recept PF00810.13 EIW69705.1 - 7.2 7.0 13.9 25 5.3 5.2 3.2 1 1 1 3 3 3 0 ER lumen protein retaining receptor Nop14 PF04147.7 EIW69706.1 - 3.3e-254 845.7 18.8 4.2e-254 845.4 13.1 1.0 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.8 EIW69706.1 - 0.078 12.8 32.7 0.17 11.7 22.7 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sterol_MT_C PF08498.5 EIW69708.1 - 5.7e-28 96.6 0.3 8.9e-28 96.0 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EIW69708.1 - 1.8e-18 66.7 0.0 3.6e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW69708.1 - 6.9e-18 64.6 0.0 9.5e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW69708.1 - 5.4e-16 58.7 0.0 8.1e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW69708.1 - 6.1e-15 55.7 0.0 6.8e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EIW69708.1 - 7.3e-14 51.4 0.0 9.8e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EIW69708.1 - 4.5e-12 46.3 0.0 1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW69708.1 - 2.2e-11 43.8 0.1 6.9e-11 42.2 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW69708.1 - 2e-10 40.9 0.0 3.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW69708.1 - 2.2e-08 33.9 0.0 3.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EIW69708.1 - 6.1e-07 28.7 0.0 1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EIW69708.1 - 6.8e-07 28.8 0.0 1.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EIW69708.1 - 2.3e-05 24.0 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.12 EIW69708.1 - 0.00027 20.0 0.0 0.00043 19.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase UPF0020 PF01170.13 EIW69708.1 - 0.00034 20.2 0.0 0.00053 19.6 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 EIW69708.1 - 0.0016 17.5 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 EIW69708.1 - 0.0038 18.0 0.0 0.015 16.1 0.0 2.0 3 0 0 3 3 1 1 Methyltransferase domain PrmA PF06325.8 EIW69708.1 - 0.015 14.3 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EIW69708.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW NodS PF05401.6 EIW69708.1 - 0.081 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EIW69708.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EIW69708.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase gag-asp_proteas PF13975.1 EIW69710.1 - 1.1e-07 31.5 0.0 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIW69710.1 - 4.5e-05 23.8 0.0 8.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.3 EIW69710.1 - 0.00092 18.5 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP_2 PF08284.6 EIW69710.1 - 0.0017 18.3 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EIW69710.1 - 0.0046 16.8 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIW69710.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF3435 PF11917.3 EIW69714.1 - 2e-21 76.2 0.0 4e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EIW69714.1 - 9.9e-06 25.3 0.0 0.00014 21.5 0.0 2.6 3 0 0 3 3 3 1 Phage integrase family Phage_integrase PF00589.17 EIW69715.1 - 0.0016 18.1 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family DUF3435 PF11917.3 EIW69715.1 - 0.0023 16.7 9.9 0.0045 15.7 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3435) Pox_Ag35 PF03286.9 EIW69715.1 - 0.024 14.1 10.1 0.063 12.7 7.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spore_coat_CotO PF14153.1 EIW69715.1 - 0.22 10.9 7.0 0.38 10.1 4.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO BSP_II PF05432.6 EIW69715.1 - 1.5 8.0 16.4 2.9 7.0 11.3 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 EIW69715.1 - 3.9 5.3 10.4 6.3 4.6 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 EIW69715.1 - 5.8 5.6 12.5 12 4.6 8.7 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein AICARFT_IMPCHas PF01808.13 EIW69716.1 - 4.2e-116 387.4 0.0 5.2e-116 387.1 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EIW69716.1 - 1.1e-23 82.9 0.0 2.7e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain DUF563 PF04577.9 EIW69719.1 - 5.4e-20 72.1 0.0 8.7e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Aldo_ket_red PF00248.16 EIW69720.1 - 5.1e-34 117.3 0.0 6.1e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HHH_2 PF12826.2 EIW69720.1 - 0.0081 16.0 0.1 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_lig_kinase PF08303.6 EIW69721.1 - 0.0032 17.3 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain Borrelia_REV PF03978.8 EIW69721.1 - 0.08 12.6 0.3 0.2 11.3 0.1 1.6 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein RVP_2 PF08284.6 EIW69724.1 - 0.00024 21.0 0.0 0.00028 20.8 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIW69724.1 - 0.0013 19.1 0.0 0.0015 18.9 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIW69724.1 - 0.043 13.6 0.1 0.06 13.1 0.0 1.5 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIW69725.1 - 8.8e-09 35.3 0.0 1.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIW69725.1 - 0.053 13.4 2.1 0.096 12.6 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle CagZ PF09053.5 EIW69725.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 CagZ Chromo PF00385.19 EIW69726.1 - 3e-09 36.3 0.8 1.2e-08 34.4 0.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Helitron_like_N PF14214.1 EIW69730.1 - 8.4e-05 22.3 0.1 0.00016 21.4 0.0 1.5 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Pox_A_type_inc PF04508.7 EIW69734.1 - 0.06 13.1 11.9 0.76 9.7 0.2 4.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Lipase_GDSL_2 PF13472.1 EIW69735.1 - 0.0042 17.2 0.0 0.016 15.3 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_transf_18 PF15024.1 EIW69736.1 - 0.00065 18.1 0.0 0.0011 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 18 WSC PF01822.14 EIW69737.1 - 7.1e-139 452.0 230.1 1.5e-16 60.0 7.7 12.1 13 0 0 13 13 13 11 WSC domain DUF1996 PF09362.5 EIW69737.1 - 7.1e-61 205.8 1.0 2e-60 204.4 0.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF563 PF04577.9 EIW69738.1 - 7.3e-20 71.7 1.3 3.8e-19 69.4 0.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Glyco_transf_18 PF15024.1 EIW69739.1 - 1.8e-12 46.3 0.0 2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 Ribosomal_L31e PF01198.14 EIW69740.1 - 1.4e-34 117.5 1.0 1.8e-34 117.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e DUF563 PF04577.9 EIW69741.1 - 1.6e-21 77.2 0.0 2.4e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DDE_3 PF13358.1 EIW69743.1 - 1.9e-12 47.1 0.0 7.3e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIW69743.1 - 4.7e-07 29.7 0.4 1.5e-06 28.1 0.1 1.9 2 0 0 2 2 2 1 Transposase DUF3400 PF11880.3 EIW69743.1 - 0.049 12.8 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) MFS_1 PF07690.11 EIW69744.1 - 1.1e-36 126.3 33.1 1.1e-36 126.3 23.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW69744.1 - 9.1e-10 37.6 21.1 8.6e-09 34.4 6.6 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter DUF2206 PF09971.4 EIW69744.1 - 0.17 10.6 0.2 0.29 9.8 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Pkinase PF00069.20 EIW69747.1 - 6.9e-52 176.1 0.0 3.3e-34 118.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69747.1 - 7.2e-25 87.5 0.0 8.3e-18 64.3 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIW69747.1 - 0.00019 21.2 0.7 0.018 14.7 0.1 3.1 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW69747.1 - 0.019 13.9 0.1 0.041 12.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like MSC PF09402.5 EIW69747.1 - 0.16 10.6 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Ribosomal_L34e PF01199.13 EIW69748.1 - 8.2e-39 131.7 6.1 1e-38 131.4 4.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e HSF_DNA-bind PF00447.12 EIW69749.1 - 2e-07 31.1 0.0 3.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding RNase_PH PF01138.16 EIW69754.1 - 1.4e-26 93.3 0.0 1.9e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 CTP_transf_1 PF01148.15 EIW69755.1 - 7.8e-09 35.5 11.4 3.3e-08 33.5 5.0 2.3 1 1 1 2 2 2 2 Cytidylyltransferase family DELLA PF12041.3 EIW69756.1 - 0.026 14.1 0.3 0.14 11.8 0.2 2.3 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal DUF3782 PF12644.2 EIW69758.1 - 0.085 12.6 0.1 5.1 6.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) XPC-binding PF09280.6 EIW69761.1 - 0.082 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 XPC-binding domain Corona_nucleoca PF00937.13 EIW69762.1 - 0.011 14.6 2.5 0.012 14.6 1.7 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4175 PF13779.1 EIW69762.1 - 2.2 5.8 8.8 2.4 5.7 6.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UBN2_3 PF14244.1 EIW69763.1 - 0.0005 19.6 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIW69763.1 - 0.0088 15.5 0.0 0.019 14.4 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Cytochrome-c551 PF10643.4 EIW69763.1 - 0.013 14.8 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 HD_4 PF13328.1 EIW69763.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 HD domain zf-CCCH PF00642.19 EIW69766.1 - 0.001 18.6 1.1 0.001 18.6 0.8 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.16 EIW69766.1 - 0.008 16.0 0.2 0.017 15.0 0.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger TAFII55_N PF04658.8 EIW69767.1 - 1.8e-47 160.8 0.1 3.7e-47 159.8 0.1 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region Vfa1 PF08432.5 EIW69767.1 - 0.089 12.8 1.5 0.21 11.5 1.0 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3983 PF13137.1 EIW69767.1 - 2.9 7.6 6.6 0.36 10.5 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) LRR_4 PF12799.2 EIW69768.1 - 2.6e-17 62.0 24.1 5.8e-09 35.3 1.1 5.9 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW69768.1 - 4.6e-12 45.5 16.1 4.9e-05 22.9 0.6 5.5 3 1 3 6 6 6 4 Leucine rich repeat LRR_7 PF13504.1 EIW69768.1 - 2.2e-06 26.9 13.5 3.4 8.2 0.1 7.6 7 0 0 7 7 7 2 Leucine rich repeat LRR_1 PF00560.28 EIW69768.1 - 2.7e-05 23.5 20.9 1.5 9.1 0.0 7.9 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.1 EIW69768.1 - 0.0024 17.7 22.1 3.8 7.8 0.0 7.9 10 0 0 10 10 10 3 Leucine Rich repeat Ribosomal_L9_N PF01281.14 EIW69769.1 - 8.8e-06 24.8 0.0 2.1e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain RAM PF15320.1 EIW69770.1 - 0.0025 18.0 0.3 0.0025 18.0 0.2 1.9 2 0 0 2 2 2 1 mRNA cap methylation, RNMT-activating mini protein PDT PF00800.13 EIW69771.1 - 1.2e-33 116.2 0.0 1.5e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase Ribosomal_S30 PF04758.9 EIW69772.1 - 3.5e-26 90.7 6.7 4.1e-26 90.5 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 HLH PF00010.21 EIW69773.1 - 2.8e-09 36.5 0.0 6.5e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MF_alpha PF04648.7 EIW69776.1 - 0.31 11.3 3.0 0.48 10.7 1.1 2.1 2 0 0 2 2 2 0 Yeast mating factor alpha hormone SIC PF03482.8 EIW69777.1 - 4.8 6.7 8.8 15 5.1 6.0 1.6 1 1 0 1 1 1 0 sic protein DDE_1 PF03184.14 EIW69778.1 - 1.2e-36 125.9 0.1 1.5e-36 125.5 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW69778.1 - 1.9e-06 27.6 0.0 3.6e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF2774 PF11242.3 EIW69778.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Resolvase PF00239.16 EIW69781.1 - 0.0075 16.1 4.5 0.014 15.2 3.1 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC PF00098.18 EIW69781.1 - 0.022 14.6 4.3 0.043 13.7 3.0 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIW69781.1 - 0.037 13.5 0.2 0.071 12.6 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIW69784.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW69784.1 - 0.34 11.1 8.4 0.087 13.0 3.7 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW69784.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Beta_protein PF14350.1 EIW69785.1 - 0.093 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta protein PepSY_2 PF13670.1 EIW69785.1 - 0.16 11.9 0.6 0.32 10.9 0.4 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Gasdermin PF04598.7 EIW69788.1 - 0.048 12.4 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 Gasdermin family UDG PF03167.14 EIW69791.1 - 4.9e-24 84.5 0.0 8.1e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Gln-synt_C PF00120.19 EIW69792.1 - 3.8e-57 193.3 0.0 7.9e-56 189.0 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain ADH_zinc_N PF00107.21 EIW69793.1 - 6.9e-11 41.8 0.0 1.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW69793.1 - 1.9e-06 27.5 0.3 4.2e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3148 PF11347.3 EIW69793.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) Mpv17_PMP22 PF04117.7 EIW69794.1 - 2.6e-24 84.6 1.7 6e-24 83.4 1.2 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family WD40 PF00400.27 EIW69795.1 - 1.4e-56 186.4 26.3 9.4e-11 41.1 0.2 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box PF00646.28 EIW69795.1 - 3.1e-09 36.2 0.2 9.1e-07 28.3 0.0 2.4 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 EIW69795.1 - 9.1e-09 34.9 0.3 3.7e-08 32.9 0.1 2.0 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 EIW69795.1 - 0.0027 15.9 10.1 0.72 7.9 1.9 5.5 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Mito_carr PF00153.22 EIW69796.1 - 2e-54 181.2 2.0 1.6e-17 62.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Plasmod_Pvs28 PF06247.6 EIW69797.1 - 0.026 14.1 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 Plasmodium ookinete surface protein Pvs28 NAD_binding_8 PF13450.1 EIW69798.1 - 1.6e-17 63.2 0.0 3.8e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW69798.1 - 4.2e-09 35.7 0.0 5.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW69798.1 - 4.2e-07 29.1 0.0 5.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW69798.1 - 6.4e-07 29.4 0.0 8.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW69798.1 - 3.4e-06 26.3 0.0 4.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIW69798.1 - 3.6e-05 24.0 0.3 0.00016 21.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW69798.1 - 0.00012 20.6 0.0 0.00019 20.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIW69798.1 - 0.00038 20.5 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW69798.1 - 0.00039 19.5 0.0 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EIW69798.1 - 0.00086 18.2 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EIW69798.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EIW69798.1 - 0.0037 16.9 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EIW69798.1 - 0.0043 16.4 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.19 EIW69798.1 - 0.005 15.9 0.0 0.0094 15.0 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EIW69798.1 - 0.023 13.6 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EIW69798.1 - 0.035 13.5 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EIW69798.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amidohydro_2 PF04909.9 EIW69799.1 - 3.7e-08 33.2 0.0 5.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EIW69799.1 - 5.9e-05 23.2 0.0 9.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Ribosomal_S15 PF00312.17 EIW69800.1 - 4.2e-16 58.4 0.1 4.2e-16 58.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S15 Mucin PF01456.12 EIW69800.1 - 9.9 5.9 20.6 16 5.2 14.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein CDP-OH_P_transf PF01066.16 EIW69801.1 - 3e-18 65.9 3.0 3.8e-18 65.6 2.1 1.3 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase CPSase_L_D2 PF02786.12 EIW69802.1 - 9.6e-62 208.0 0.0 1.3e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EIW69802.1 - 9.1e-37 125.5 0.1 4.4e-36 123.3 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EIW69802.1 - 2.8e-12 46.7 0.0 5.2e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIW69802.1 - 2e-10 39.9 0.0 6.6e-10 38.2 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EIW69802.1 - 5.4e-07 29.1 0.0 1.4e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIW69802.1 - 6e-05 22.5 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EIW69802.1 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain Biotin_carb_C PF02785.14 EIW69802.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain DUF3182 PF11379.3 EIW69802.1 - 0.097 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Gly_transf_sug PF04488.10 EIW69803.1 - 1.8e-05 25.0 0.0 3.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIW69803.1 - 0.034 13.3 1.2 0.048 12.8 0.2 1.6 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein Glyco_transf_8 PF01501.15 EIW69803.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 TrkH PF02386.11 EIW69804.1 - 5.5e-89 298.1 14.8 5e-87 291.7 1.5 2.2 2 0 0 2 2 2 2 Cation transport protein Ribul_P_3_epim PF00834.14 EIW69805.1 - 2.7e-59 199.6 0.0 3.2e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PcrB PF01884.12 EIW69805.1 - 0.034 13.3 0.0 0.068 12.4 0.0 1.6 1 0 0 1 1 1 0 PcrB family HSP70 PF00012.15 EIW69805.1 - 0.11 10.3 0.1 0.16 9.8 0.1 1.1 1 0 0 1 1 1 0 Hsp70 protein zf-CCHC PF00098.18 EIW69807.1 - 0.00037 20.2 1.3 0.00076 19.2 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW69807.1 - 0.096 12.3 1.4 0.45 10.2 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF605 PF04652.11 EIW69808.1 - 2.6 7.3 20.3 2.9 7.1 14.1 1.0 1 0 0 1 1 1 0 Vta1 like DEAD PF00270.24 EIW69811.1 - 1.7e-40 138.2 0.1 8.2e-39 132.7 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW69811.1 - 6.6e-25 86.7 0.3 1.3e-24 85.8 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIW69811.1 - 0.00047 19.0 0.0 0.00075 18.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2986 PF11661.3 EIW69811.1 - 0.0023 18.1 3.7 0.0083 16.4 2.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) Helicase_C_2 PF13307.1 EIW69811.1 - 0.012 15.5 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain ResIII PF04851.10 EIW69811.1 - 0.048 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PAS_10 PF13596.1 EIW69811.1 - 0.06 13.6 0.2 0.52 10.6 0.1 2.4 2 0 0 2 2 2 0 PAS domain EF_TS PF00889.14 EIW69811.1 - 3.3 6.9 8.1 18 4.5 0.0 3.2 2 1 0 3 3 3 0 Elongation factor TS Fasciclin PF02469.17 EIW69812.1 - 1.9e-17 63.4 4.9 1e-10 41.6 0.0 3.2 3 1 0 3 3 3 2 Fasciclin domain DUF575 PF04746.7 EIW69812.1 - 0.088 12.8 1.3 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF575) Alpha_GJ PF03229.8 EIW69812.1 - 1 9.6 9.4 2.6 8.4 1.0 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF563 PF04577.9 EIW69813.1 - 5.2e-22 78.7 0.1 1.1e-21 77.7 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) SpoU_methylase PF00588.14 EIW69813.1 - 0.15 11.9 0.0 1 9.1 0.0 2.0 2 0 0 2 2 2 0 SpoU rRNA Methylase family PTP_N PF12453.3 EIW69813.1 - 1.2 8.7 4.4 0.26 10.9 0.2 1.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal CD99L2 PF12301.3 EIW69814.1 - 0.0032 17.1 0.1 1.9 8.1 0.0 2.2 2 0 0 2 2 2 2 CD99 antigen like protein 2 Glyco_hydro_38 PF01074.17 EIW69817.1 - 1.2e-76 257.5 0.0 2e-76 256.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EIW69817.1 - 1.6e-58 198.6 0.0 2.2e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EIW69817.1 - 4.4e-25 87.6 0.0 9.1e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain HSBP1 PF06825.7 EIW69818.1 - 0.36 10.4 4.1 5 6.7 0.2 3.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Epimerase PF01370.16 EIW69819.1 - 3.3e-42 144.5 0.0 4.4e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EIW69819.1 - 1.8e-23 82.2 0.0 3.4e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EIW69819.1 - 4.9e-15 54.9 0.0 5.1e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIW69819.1 - 1.3e-10 40.6 0.0 9.4e-10 37.8 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EIW69819.1 - 2.6e-10 40.4 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIW69819.1 - 7.1e-10 38.2 0.0 1.5e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EIW69819.1 - 7.9e-08 31.5 0.0 1.5e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EIW69819.1 - 5.9e-07 29.3 0.0 1.2e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW69819.1 - 0.047 13.7 0.1 1 9.2 0.1 2.3 1 1 0 1 1 1 0 NADH(P)-binding CAP59_mtransfer PF11735.3 EIW69820.1 - 1.1e-49 168.9 0.0 2.5e-49 167.7 0.0 1.6 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 Isochorismatase PF00857.15 EIW69821.1 - 1.3e-22 80.5 0.0 4.9e-22 78.6 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family Plasmodium_Vir PF05795.6 EIW69822.1 - 0.18 10.9 0.9 0.25 10.5 0.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pex14_N PF04695.8 EIW69822.1 - 0.32 11.0 10.9 3.6 7.6 7.1 2.7 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP1 PF08601.5 EIW69822.1 - 0.44 10.1 12.9 0.61 9.7 8.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Pol_alpha_B_N PF08418.5 EIW69822.1 - 5.9 6.3 10.4 8.5 5.8 7.2 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Kelch_6 PF13964.1 EIW69823.1 - 1.1e-17 63.3 0.6 7.4e-07 29.0 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EIW69823.1 - 4e-15 55.3 0.1 5.4e-06 26.0 0.0 4.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EIW69823.1 - 7.8e-14 50.9 0.4 1.4e-05 24.5 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EIW69823.1 - 1.1e-12 47.1 6.3 2.4e-06 27.0 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 EIW69823.1 - 2e-12 46.7 1.2 3.1e-05 23.7 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 EIW69823.1 - 2.1e-10 40.4 3.2 7.1e-05 22.8 0.1 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain BTB PF00651.26 EIW69823.1 - 0.0022 17.9 0.4 0.056 13.4 0.3 2.3 1 1 0 1 1 1 1 BTB/POZ domain UCH PF00443.24 EIW69824.1 - 1e-65 221.5 0.0 1.5e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW69824.1 - 2.9e-17 63.0 0.0 9.6e-17 61.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EIW69824.1 - 2e-05 24.9 0.0 4.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.6 EIW69824.1 - 0.0026 17.7 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Phage_GPL PF05926.6 EIW69824.1 - 0.042 13.6 0.3 0.081 12.7 0.2 1.4 1 0 0 1 1 1 0 Phage head completion protein (GPL) RseC_MucC PF04246.7 EIW69825.1 - 0.79 9.2 0.0 0.79 9.2 0.0 1.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4131 PF13567.1 EIW69825.1 - 9.1 5.6 7.4 37 3.6 5.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) SLD3 PF08639.5 EIW69826.1 - 1.7e-16 59.9 2.7 2.5e-16 59.4 1.8 1.3 1 0 0 1 1 1 1 DNA replication regulator SLD3 DUF1133 PF06576.6 EIW69826.1 - 0.14 11.2 0.1 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) ABC_tran PF00005.22 EIW69827.1 - 2.2e-06 27.9 0.0 3.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EIW69827.1 - 0.0011 18.2 0.1 0.0015 17.7 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EIW69827.1 - 0.048 13.5 0.0 1.1 9.2 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC2_membrane PF01061.19 EIW69828.1 - 6.5e-82 273.7 66.2 3.5e-43 147.2 16.9 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EIW69828.1 - 1.3e-33 116.2 0.0 3.8e-16 59.6 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EIW69828.1 - 6.8e-33 112.4 2.1 5.7e-25 86.9 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EIW69828.1 - 3e-08 33.6 0.1 1.4e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EIW69828.1 - 3.5e-06 26.5 0.1 0.0065 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW69828.1 - 0.0011 19.0 0.0 0.21 11.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 EIW69828.1 - 0.0013 18.2 0.0 0.0041 16.5 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EIW69828.1 - 0.0017 18.2 0.0 0.025 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EIW69828.1 - 0.0023 17.0 50.3 0.007 15.4 11.7 3.3 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_29 PF13555.1 EIW69828.1 - 0.0025 17.3 0.4 0.0079 15.6 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EIW69828.1 - 0.0026 16.9 0.1 0.0087 15.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EIW69828.1 - 0.0034 17.3 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EIW69828.1 - 0.0064 16.1 1.3 0.3 10.7 0.2 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EIW69828.1 - 0.022 14.7 0.3 0.079 12.9 0.1 2.0 2 1 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW69828.1 - 0.029 13.8 0.3 15 4.9 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EIW69828.1 - 0.031 14.2 0.6 0.1 12.6 0.2 2.1 2 1 0 2 2 1 0 AAA ATPase domain SMC_N PF02463.14 EIW69828.1 - 0.032 13.4 0.0 1.2 8.2 0.0 3.0 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EIW69828.1 - 0.035 14.0 0.0 8.8 6.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EIW69828.1 - 0.035 14.3 0.0 0.094 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW69828.1 - 0.047 14.5 0.0 0.17 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EIW69828.1 - 0.31 11.3 0.1 0.65 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Aldedh PF00171.17 EIW69829.1 - 1.6e-118 396.0 0.0 1.8e-118 395.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cation_efflux PF01545.16 EIW69831.1 - 1.3e-51 175.4 5.2 8.3e-51 172.7 3.6 1.9 1 1 0 1 1 1 1 Cation efflux family Na_Ca_ex PF01699.19 EIW69832.1 - 1.2e-40 138.3 32.0 2.7e-23 82.1 6.7 3.2 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DEAD PF00270.24 EIW69833.1 - 6.9e-41 139.5 0.0 1.4e-40 138.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EIW69833.1 - 4.6e-23 80.5 0.2 1.1e-22 79.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EIW69833.1 - 1.4e-22 79.3 0.0 3.5e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW69833.1 - 0.005 16.6 0.2 0.045 13.5 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EIW69833.1 - 0.099 12.5 0.1 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain DUF726 PF05277.7 EIW69835.1 - 1.5e-50 172.0 3.9 8.1e-40 136.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF726) PE-PPE PF08237.6 EIW69835.1 - 0.16 11.3 0.0 0.61 9.4 0.0 1.9 2 0 0 2 2 2 0 PE-PPE domain DUF2076 PF09849.4 EIW69835.1 - 9.8 6.1 7.8 56 3.6 5.4 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) OB_NTP_bind PF07717.11 EIW69836.1 - 3.9e-16 58.9 0.0 9.9e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EIW69836.1 - 4.3e-16 58.8 0.0 8.5e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIW69836.1 - 2.2e-12 46.6 0.0 5e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EIW69836.1 - 0.0034 17.5 0.3 0.057 13.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIW69836.1 - 0.013 14.6 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIW69836.1 - 0.046 14.0 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.10 EIW69836.1 - 0.046 13.5 0.1 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EIW69836.1 - 0.11 11.3 0.0 0.4 9.5 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein MFS_1 PF07690.11 EIW69837.1 - 3.4e-39 134.5 28.0 3.4e-39 134.5 19.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PLAC8 PF04749.12 EIW69837.1 - 0.088 13.3 1.0 0.36 11.3 0.1 2.3 2 0 0 2 2 2 0 PLAC8 family Mit_ribos_Mrp51 PF11709.3 EIW69838.1 - 8e-12 44.9 1.3 1.8e-11 43.8 0.9 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit PAP2 PF01569.16 EIW69839.1 - 1.2e-25 89.6 2.9 1.2e-25 89.6 2.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily DUF3860 PF12976.2 EIW69839.1 - 0.26 11.1 1.4 1.9 8.3 0.0 2.6 2 1 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3860) Zn_clus PF00172.13 EIW69840.1 - 2.5e-05 24.1 9.2 3.7e-05 23.5 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LUC7 PF03194.10 EIW69842.1 - 0.0041 16.6 1.9 0.0046 16.5 0.3 1.7 1 1 0 1 1 1 1 LUC7 N_terminus IncA PF04156.9 EIW69842.1 - 0.29 10.6 6.9 0.47 10.0 4.8 1.5 1 1 0 1 1 1 0 IncA protein CDC45 PF02724.9 EIW69843.1 - 0.0091 14.0 0.9 0.014 13.4 0.6 1.2 1 0 0 1 1 1 1 CDC45-like protein DUF3391 PF11871.3 EIW69843.1 - 0.067 13.3 0.7 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Rhabdo_ncap PF00945.13 EIW69843.1 - 0.24 9.9 1.5 0.37 9.3 1.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Peptidase_M13_N PF05649.8 EIW69844.1 - 0.0014 17.8 2.7 0.0016 17.5 1.9 1.1 1 0 0 1 1 1 1 Peptidase family M13 TBPIP PF07106.8 EIW69844.1 - 0.016 14.7 4.5 0.16 11.5 2.1 2.5 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CAML PF14963.1 EIW69844.1 - 6.7 5.9 7.8 9.1 5.5 5.1 1.4 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Cellulase PF00150.13 EIW69846.1 - 9.7e-21 74.1 10.0 1.8e-20 73.2 6.9 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ricin_B_lectin PF00652.17 EIW69846.1 - 1.9e-18 66.6 5.5 7.7e-11 42.0 0.9 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIW69846.1 - 9.1e-13 48.4 12.5 8.5e-09 35.7 3.5 3.3 3 1 1 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Macoilin PF09726.4 EIW69846.1 - 0.67 8.1 3.4 0.86 7.8 2.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Chs3p PF12271.3 EIW69847.1 - 2.2e-53 181.1 14.8 3.5e-50 170.6 8.4 2.0 2 0 0 2 2 2 2 Chitin synthase III catalytic subunit UBN2_3 PF14244.1 EIW69848.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIW69848.1 - 0.0098 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Gtr1_RagA PF04670.7 EIW69853.1 - 6.1e-86 287.3 0.0 8.8e-86 286.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EIW69853.1 - 9.4e-08 31.6 0.1 1.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EIW69853.1 - 2.6e-06 26.8 0.0 3.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EIW69853.1 - 3.7e-06 27.4 0.0 8.6e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW69853.1 - 8e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EIW69853.1 - 0.0056 16.9 0.1 0.016 15.4 0.1 1.7 1 1 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.22 EIW69853.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EIW69853.1 - 0.028 13.9 0.1 0.068 12.6 0.1 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EIW69853.1 - 0.04 13.4 0.2 0.082 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 EIW69853.1 - 0.065 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CFC PF09443.5 EIW69853.1 - 0.13 11.9 0.4 7.8 6.2 0.3 2.4 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Sigma54_activat PF00158.21 EIW69853.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 EIW69853.1 - 0.19 10.6 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 EIW69853.1 - 0.2 11.1 0.3 22 4.4 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF2461 PF09365.5 EIW69854.1 - 3.1e-66 222.8 0.2 3.5e-66 222.6 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Diphthamide_syn PF01866.12 EIW69855.1 - 3e-88 296.0 0.0 1.1e-57 195.6 0.0 2.3 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Nod_GRP PF07806.6 EIW69855.1 - 0.19 11.3 4.9 0.38 10.4 3.4 1.4 1 0 0 1 1 1 0 Nodule-specific GRP repeat cwf18 PF08315.7 EIW69856.1 - 1.6e-29 102.9 7.0 1.6e-29 102.9 4.8 1.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor MTHFR PF02219.12 EIW69857.1 - 2.1e-103 345.3 0.0 3.2e-103 344.7 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase FUSC_2 PF13515.1 EIW69858.1 - 9.7e-21 74.0 10.2 9.7e-21 74.0 7.1 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.7 EIW69858.1 - 1.4e-08 33.6 7.3 1.4e-08 33.6 5.0 4.1 4 0 0 4 4 4 1 Fusaric acid resistance protein family ALMT PF11744.3 EIW69858.1 - 5.8e-05 21.9 11.8 0.00013 20.8 5.8 2.9 2 1 0 2 2 2 1 Aluminium activated malate transporter zf-RING_2 PF13639.1 EIW69860.1 - 8e-11 41.5 4.5 1.3e-10 40.9 3.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW69860.1 - 1.5e-08 34.5 3.4 2.4e-08 33.8 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW69860.1 - 3.6e-08 32.9 3.1 5.8e-08 32.2 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) IATP PF04568.7 EIW69860.1 - 7.9e-08 32.2 0.2 1.6e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP zf-RING_5 PF14634.1 EIW69860.1 - 1.7e-06 27.6 3.1 2.7e-06 27.0 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIW69860.1 - 5.6e-05 23.1 0.7 9.9e-05 22.3 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EIW69860.1 - 0.00055 19.5 1.7 0.0011 18.5 1.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EIW69860.1 - 0.0047 16.1 0.5 0.0047 16.1 0.3 2.2 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 EIW69860.1 - 0.02 14.5 2.3 0.037 13.7 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW69860.1 - 0.035 13.9 1.1 0.064 13.1 0.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EIW69860.1 - 0.043 13.5 4.5 0.077 12.7 0.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 EAP30 PF04157.11 EIW69860.1 - 0.15 11.2 0.2 0.25 10.4 0.2 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family RINGv PF12906.2 EIW69860.1 - 0.92 9.6 4.2 1.6 8.7 2.9 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EIW69860.1 - 0.99 9.4 2.4 1.8 8.5 1.6 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain EF-hand_6 PF13405.1 EIW69861.1 - 1.6e-13 49.2 0.0 8.6e-05 22.1 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 EIW69861.1 - 3.1e-13 49.6 0.0 2.2e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EIW69861.1 - 3.9e-11 41.4 0.0 0.0015 17.6 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 EIW69861.1 - 2e-06 27.6 0.0 0.00088 19.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EIW69861.1 - 1.3e-05 24.7 0.3 0.001 18.6 0.0 3.0 3 1 1 4 4 4 1 EF-hand domain pair UPF0154 PF03672.8 EIW69861.1 - 0.0013 18.2 0.0 0.29 10.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 EIW69861.1 - 0.004 16.4 0.0 3.9 6.9 0.0 3.0 3 0 0 3 3 3 2 EF hand Big_3_2 PF12245.3 EIW69861.1 - 0.011 15.2 0.2 0.028 13.9 0.1 1.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF2267 PF10025.4 EIW69861.1 - 0.14 12.1 0.0 2 8.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DEAD PF00270.24 EIW69862.1 - 2.4e-45 154.0 0.0 3.4e-44 150.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW69862.1 - 3.6e-26 90.8 0.1 6.9e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW69862.1 - 0.0023 17.7 0.0 0.0071 16.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIW69862.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 EIW69862.1 - 0.22 11.4 0.0 0.44 10.4 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain DUF427 PF04248.7 EIW69863.1 - 3e-21 74.8 0.6 3.4e-21 74.7 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) MFS_1 PF07690.11 EIW69864.1 - 4.9e-31 107.7 85.5 3.1e-28 98.4 38.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.9 EIW69865.1 - 5.4e-28 98.2 0.0 5.7e-27 94.9 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW69865.1 - 1e-12 48.2 0.2 9.4e-11 41.9 0.0 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW69865.1 - 0.00081 19.5 0.1 2.3 8.2 0.0 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase TPPII_N PF12583.3 EIW69865.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Methyltransf_16 PF10294.4 EIW69867.1 - 4.5e-50 169.4 0.0 5.8e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIW69867.1 - 3e-05 24.5 0.0 4.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW69867.1 - 0.0019 17.5 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EIW69867.1 - 0.0056 16.2 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EIW69867.1 - 0.034 13.2 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PrmA PF06325.8 EIW69867.1 - 0.053 12.6 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HTH_8 PF02954.14 EIW69868.1 - 0.0023 17.4 3.0 1.9 8.1 0.7 3.1 2 0 0 2 2 2 2 Bacterial regulatory protein, Fis family HBS1_N PF08938.5 EIW69868.1 - 0.074 13.1 0.5 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 HBS1 N-terminus Sec5 PF15469.1 EIW69869.1 - 1.5e-50 171.4 1.8 5.2e-50 169.6 0.0 2.7 3 0 0 3 3 3 1 Exocyst complex component Sec5 ATP-grasp_2 PF08442.5 EIW69870.1 - 9.2e-74 247.1 0.2 1.5e-73 246.5 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EIW69870.1 - 6.8e-24 84.2 0.3 1.4e-23 83.2 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EIW69870.1 - 1.4e-10 40.7 0.3 4.7e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EIW69870.1 - 9e-05 22.1 0.0 0.0013 18.3 0.0 2.2 1 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EIW69870.1 - 0.0074 16.0 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Lipase_GDSL_2 PF13472.1 EIW69871.1 - 2.2e-06 27.9 0.1 3.9e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.20 EIW69872.1 - 1.7e-52 178.1 0.0 5.9e-52 176.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69872.1 - 3.5e-23 81.9 0.0 5.7e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW69872.1 - 0.0077 15.9 0.1 0.054 13.2 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW69872.1 - 0.31 9.9 0.0 0.53 9.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Sugar_tr PF00083.19 EIW69873.1 - 2.4e-54 184.6 17.1 3.6e-54 184.0 11.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW69873.1 - 3.7e-11 42.3 26.7 3.7e-11 42.3 18.5 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily STAG PF08514.6 EIW69874.1 - 5.6e-24 84.1 0.3 2.5e-23 82.0 0.2 2.2 1 0 0 1 1 1 1 STAG domain HEAT PF02985.17 EIW69874.1 - 1.5e-05 24.6 5.1 4 7.7 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EIW69874.1 - 7.3e-05 22.9 3.9 0.0043 17.3 0.0 4.4 4 1 1 5 5 5 2 HEAT repeats UQ_con PF00179.21 EIW69876.1 - 3.8e-48 162.4 0.0 4.8e-48 162.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW69876.1 - 4.4e-06 26.4 0.0 5.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIW69876.1 - 0.059 13.2 0.1 0.14 12.0 0.1 1.8 1 1 1 2 2 2 0 RWD domain Cation_efflux PF01545.16 EIW69877.1 - 1.6e-10 40.5 4.8 3.6e-10 39.3 3.3 1.4 1 1 0 1 1 1 1 Cation efflux family Glyco_transf_90 PF05686.7 EIW69878.1 - 4.3e-09 35.5 0.0 6.2e-07 28.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 90 zf-rbx1 PF12678.2 EIW69879.1 - 5.9e-09 35.9 0.3 1.3e-08 34.8 0.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EIW69879.1 - 3.5e-07 29.9 10.8 8e-07 28.7 5.9 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EIW69879.1 - 2.2e-06 27.2 1.5 4.3e-06 26.2 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW69879.1 - 2.6e-05 23.8 1.4 6.7e-05 22.5 1.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW69879.1 - 0.00041 19.9 3.3 0.0016 18.1 2.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW69879.1 - 0.00068 19.6 6.5 0.00087 19.2 1.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW69879.1 - 0.00095 18.9 0.5 0.0025 17.6 0.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 EIW69879.1 - 0.32 10.5 4.9 0.97 8.9 3.4 1.7 1 0 0 1 1 1 0 P-11 zinc finger bZIP_1 PF00170.16 EIW69879.1 - 1.2 9.0 9.7 0.053 13.4 2.6 1.8 2 0 0 2 2 2 0 bZIP transcription factor Baculo_PEP_C PF04513.7 EIW69880.1 - 0.00018 21.3 2.4 0.00039 20.2 0.3 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus FtsK_SpoIIIE PF01580.13 EIW69880.1 - 0.03 13.7 1.1 0.072 12.5 0.8 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family SidE PF12252.3 EIW69880.1 - 0.086 10.1 4.1 0.12 9.6 2.8 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Cep57_CLD_2 PF14197.1 EIW69880.1 - 0.094 12.6 5.0 0.28 11.1 3.4 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Apolipoprotein PF01442.13 EIW69880.1 - 0.16 11.4 6.1 0.17 11.3 2.9 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain PMC2NT PF08066.7 EIW69880.1 - 0.25 11.6 2.8 0.93 9.8 1.5 2.4 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Syntaxin-6_N PF09177.6 EIW69880.1 - 0.34 11.3 7.7 0.56 10.6 2.1 3.0 2 2 1 3 3 3 0 Syntaxin 6, N-terminal IncA PF04156.9 EIW69880.1 - 1.7 8.2 6.7 4.3 6.8 4.6 1.6 1 0 0 1 1 1 0 IncA protein IFT57 PF10498.4 EIW69880.1 - 3.2 6.4 12.3 0.074 11.7 3.9 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.7 EIW69880.1 - 3.3 7.5 6.6 1.3 8.7 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 EIW69880.1 - 9.2 6.4 11.2 4.2 7.5 2.2 3.5 3 1 1 4 4 4 0 Syntaxin Transposase_21 PF02992.9 EIW69881.1 - 3.2e-10 39.4 0.0 3.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 His_biosynth PF00977.16 EIW69882.1 - 3.9e-44 150.6 2.3 6.1e-42 143.4 1.6 3.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EIW69882.1 - 3.8e-20 72.1 0.0 6.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EIW69882.1 - 2.9e-08 33.4 0.0 1.4e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 EIW69882.1 - 1.1e-05 25.1 0.0 0.0039 16.8 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Aminotran_1_2 PF00155.16 EIW69883.1 - 1.4e-39 136.1 0.0 2.8e-39 135.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIW69883.1 - 0.00046 18.5 0.0 0.00077 17.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme N2227 PF07942.7 EIW69884.1 - 2.4e-81 272.6 0.0 4.4e-81 271.8 0.0 1.4 1 0 0 1 1 1 1 N2227-like protein DUF1669 PF07894.7 EIW69884.1 - 0.022 13.9 1.1 0.033 13.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) Zip PF02535.17 EIW69884.1 - 0.84 8.5 9.7 1.2 8.0 6.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Lin-8 PF03353.10 EIW69884.1 - 1.9 7.6 5.4 2.7 7.1 3.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NT-C2 PF10358.4 EIW69885.1 - 1.5e-06 27.7 0.0 0.0029 17.1 0.0 2.7 2 1 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Gly_transf_sug PF04488.10 EIW69886.1 - 2.3e-09 37.5 0.0 4.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif ArfGap PF01412.13 EIW69887.1 - 2.5e-39 133.6 0.0 3.7e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Lamprin PF06403.6 EIW69887.1 - 1.9 8.2 15.8 4.1 7.1 10.9 1.6 1 0 0 1 1 1 0 Lamprin Joubert PF15392.1 EIW69888.1 - 0.061 12.5 0.9 0.11 11.7 0.6 1.4 1 0 0 1 1 1 0 Joubert syndrome-associated DEAD PF00270.24 EIW69889.1 - 3e-37 127.7 0.2 5.7e-37 126.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW69889.1 - 4.2e-26 90.6 0.0 2.2e-25 88.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW69889.1 - 8e-06 25.8 0.1 2.3e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EIW69889.1 - 0.023 13.4 0.0 0.04 12.7 0.0 1.3 1 1 0 1 1 1 0 SNF2 family N-terminal domain SNF5 PF04855.7 EIW69890.1 - 9.7e-69 231.5 0.2 9.7e-69 231.5 0.1 1.8 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EIW69890.1 - 0.13 11.6 2.3 0.34 10.2 1.6 1.8 1 0 0 1 1 1 0 GATA zinc finger Podoplanin PF05808.6 EIW69890.1 - 0.52 9.8 2.1 1.3 8.5 1.5 1.7 1 0 0 1 1 1 0 Podoplanin FYDLN_acid PF09538.5 EIW69890.1 - 1.3 9.6 9.9 0.33 11.5 3.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) ABC_membrane PF00664.18 EIW69891.1 - 3.2e-87 292.4 21.8 1.3e-47 162.4 6.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW69891.1 - 1.5e-68 229.3 0.0 3.6e-33 114.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIW69891.1 - 5.7e-14 51.8 0.0 0.0002 20.6 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW69891.1 - 6.9e-10 39.3 0.0 0.41 10.5 0.0 4.3 3 1 0 4 4 4 2 AAA domain ABC_ATPase PF09818.4 EIW69891.1 - 3.1e-09 35.9 1.1 0.0011 17.7 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EIW69891.1 - 2.2e-08 33.4 0.1 0.0024 17.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW69891.1 - 7.7e-08 33.1 0.0 0.031 15.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIW69891.1 - 1.3e-07 31.7 1.9 0.031 14.2 0.1 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EIW69891.1 - 2.2e-06 27.8 0.7 0.058 13.5 0.1 4.0 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 EIW69891.1 - 6e-06 25.5 0.0 0.065 12.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EIW69891.1 - 2.7e-05 23.9 2.6 0.11 12.4 0.2 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EIW69891.1 - 5.5e-05 23.0 0.4 0.36 10.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 EIW69891.1 - 6.4e-05 23.1 2.3 0.03 14.5 0.1 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EIW69891.1 - 0.00034 20.3 0.0 1.1 9.0 0.0 3.2 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EIW69891.1 - 0.00038 19.6 0.0 0.46 9.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 EIW69891.1 - 0.00057 19.8 0.2 1.1 9.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EIW69891.1 - 0.00068 19.3 1.3 1.3 8.7 0.0 4.0 6 0 0 6 6 4 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EIW69891.1 - 0.00094 19.4 0.0 1.6 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EIW69891.1 - 0.002 18.0 0.0 2 8.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_23 PF13476.1 EIW69891.1 - 0.0023 18.2 0.2 5.1 7.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EIW69891.1 - 0.0029 17.0 0.3 2.2 7.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 EIW69891.1 - 0.0036 16.2 0.1 0.71 8.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.17 EIW69891.1 - 0.0044 17.1 0.0 2.7 8.2 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_19 PF13245.1 EIW69891.1 - 0.0076 15.9 2.1 0.96 9.2 0.0 3.4 3 0 0 3 3 2 1 Part of AAA domain NACHT PF05729.7 EIW69891.1 - 0.0097 15.5 0.1 5.4 6.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.10 EIW69891.1 - 0.013 14.2 0.0 0.035 12.8 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 EIW69891.1 - 0.02 14.3 0.2 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PRK PF00485.13 EIW69891.1 - 0.023 14.2 0.0 4.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 EIW69891.1 - 0.025 14.0 2.2 4.6 6.5 0.0 3.1 4 0 0 4 4 3 0 AAA-like domain MMR_HSR1 PF01926.18 EIW69891.1 - 0.029 14.3 0.0 8.6 6.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 EIW69891.1 - 0.04 13.0 0.0 0.95 8.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.15 EIW69891.1 - 0.047 12.3 5.8 0.36 9.4 0.0 2.8 3 0 0 3 3 2 0 G-protein alpha subunit APS_kinase PF01583.15 EIW69891.1 - 0.062 12.9 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Miro PF08477.8 EIW69891.1 - 0.11 12.9 0.0 28 5.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein DUF87 PF01935.12 EIW69891.1 - 0.17 11.6 3.1 2.5 7.8 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 DUF308 PF03729.8 EIW69892.1 - 0.042 13.8 0.4 0.042 13.8 0.3 2.7 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) GWT1 PF06423.7 EIW69892.1 - 0.83 9.7 3.1 0.97 9.5 0.3 2.0 1 1 1 2 2 2 0 GWT1 TBCC PF07986.7 EIW69893.1 - 0.00028 20.2 0.8 0.0022 17.4 0.0 2.7 3 0 0 3 3 3 1 Tubulin binding cofactor C 6PF2K PF01591.13 EIW69894.1 - 1.1e-57 194.6 0.0 1.7e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIW69894.1 - 2.3e-14 53.8 0.0 3.9e-13 49.8 0.0 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EIW69894.1 - 2.1e-05 25.3 0.1 0.0001 23.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW69894.1 - 0.0004 20.2 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EIW69894.1 - 0.0019 17.4 0.0 0.0074 15.5 0.0 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 TPR_14 PF13428.1 EIW69895.1 - 4.2e-06 26.9 2.4 2 9.3 0.1 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW69895.1 - 2.1e-05 24.0 0.3 0.72 9.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW69895.1 - 3.2e-05 24.4 0.7 0.23 12.1 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIW69895.1 - 8.2e-05 22.1 0.1 1 9.0 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_15 PF13429.1 EIW69895.1 - 0.00013 21.1 0.4 0.00035 19.7 0.2 1.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW69895.1 - 0.0041 16.6 0.3 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW69895.1 - 0.013 15.2 0.3 0.12 12.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW69895.1 - 0.017 14.8 0.9 0.14 12.0 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIW69895.1 - 0.02 14.8 2.5 0.062 13.2 0.6 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat HEAT_2 PF13646.1 EIW69895.1 - 0.028 14.6 0.6 0.37 11.1 0.2 2.4 1 1 0 2 2 2 0 HEAT repeats TPR_19 PF14559.1 EIW69895.1 - 0.11 12.9 0.7 21 5.5 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat YCII PF03795.9 EIW69896.1 - 0.00045 20.3 0.0 0.00098 19.2 0.0 1.5 1 1 0 1 1 1 1 YCII-related domain HMG_box PF00505.14 EIW69897.1 - 1.2e-11 44.6 0.5 2.5e-11 43.6 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW69897.1 - 0.0043 17.3 0.7 0.012 16.0 0.5 1.8 1 1 0 1 1 1 1 HMG-box domain VPS9 PF02204.13 EIW69899.1 - 1.1e-17 63.9 0.0 4.5e-15 55.5 0.0 2.4 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain DDE_Tnp_1_4 PF13701.1 EIW69899.1 - 0.04 12.0 0.1 0.071 11.2 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain group 1 FAT PF02259.18 EIW69900.1 - 3.9e-60 203.7 0.0 8.8e-60 202.5 0.0 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EIW69900.1 - 1.9e-20 73.3 0.7 5.1e-20 71.9 0.5 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_11 PF13414.1 EIW69900.1 - 0.0013 18.3 0.4 1.8 8.2 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EIW69900.1 - 0.0042 17.0 0.1 0.41 10.6 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3384 PF11864.3 EIW69900.1 - 0.012 14.1 0.1 0.062 11.7 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) TPR_7 PF13176.1 EIW69900.1 - 0.014 15.1 0.2 0.11 12.3 0.2 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat FATC PF02260.15 EIW69900.1 - 0.038 13.4 0.4 0.1 12.0 0.2 1.7 1 0 0 1 1 1 0 FATC domain TPR_2 PF07719.12 EIW69900.1 - 0.038 13.8 0.2 1 9.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW69900.1 - 0.12 12.1 0.2 2.5 8.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MCR_alpha_N PF02745.10 EIW69900.1 - 0.14 11.2 0.2 0.29 10.3 0.1 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain PPR PF01535.15 EIW69900.1 - 0.15 12.1 0.0 56 4.0 0.0 3.9 3 0 0 3 3 3 0 PPR repeat IncA PF04156.9 EIW69901.1 - 0.068 12.7 1.5 0.095 12.2 1.1 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EIW69901.1 - 0.67 9.4 5.6 5.3 6.5 2.0 2.5 2 1 1 3 3 3 0 Septum formation initiator DUF1308 PF07000.6 EIW69902.1 - 2.3e-19 69.2 0.0 1.9e-18 66.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Stathmin PF00836.14 EIW69902.1 - 0.041 13.5 0.3 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Stathmin family Mito_carr PF00153.22 EIW69903.1 - 1.4e-58 194.6 1.0 1.9e-18 65.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Nuf2 PF03800.9 EIW69905.1 - 6.7e-39 133.1 0.5 3.3e-38 130.9 0.0 2.2 2 1 1 3 3 3 1 Nuf2 family GAS PF13851.1 EIW69905.1 - 0.0018 17.5 36.1 0.0042 16.3 4.3 3.2 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 EIW69905.1 - 0.65 10.0 32.9 0.33 10.9 1.9 4.4 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF1409 PF07197.7 EIW69905.1 - 0.87 9.6 8.4 0.24 11.4 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1409) V_ATPase_I PF01496.14 EIW69905.1 - 5.3 4.7 26.5 16 3.1 18.4 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.14 EIW69905.1 - 7 6.1 38.6 2.2 7.7 11.9 2.7 1 1 0 2 2 2 0 Ezrin/radixin/moesin family HALZ PF02183.13 EIW69905.1 - 9 6.1 12.0 7.3 6.4 0.1 4.3 3 2 1 4 4 4 0 Homeobox associated leucine zipper Filament PF00038.16 EIW69905.1 - 9.4 5.6 38.8 0.15 11.4 6.7 3.4 1 1 1 2 2 2 0 Intermediate filament protein APG6 PF04111.7 EIW69905.1 - 9.8 5.1 35.9 0.68 8.9 4.8 3.2 1 1 2 3 3 3 0 Autophagy protein Apg6 Cnd3 PF12719.2 EIW69906.1 - 1.1e-79 267.5 4.8 2.2e-79 266.5 2.9 1.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 EIW69906.1 - 9.1e-09 34.6 6.6 0.46 10.7 0.0 6.9 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EIW69906.1 - 2.1e-08 34.3 14.1 0.023 14.9 0.6 5.5 4 2 1 5 5 5 4 HEAT repeats Cohesin_HEAT PF12765.2 EIW69906.1 - 0.014 15.3 2.3 14 5.7 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 EIW69906.1 - 0.06 13.8 8.5 0.77 10.3 1.4 4.7 4 1 1 5 5 5 0 HEAT-like repeat Pkinase PF00069.20 EIW69907.1 - 7.4e-44 149.8 0.0 4.2e-26 91.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69907.1 - 1e-14 54.2 0.0 4.7e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIW69907.1 - 1.4e-05 24.9 0.1 0.0021 17.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW69907.1 - 0.00049 19.1 0.0 1.1 8.1 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EIW69907.1 - 0.027 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PALP PF00291.20 EIW69908.1 - 2.4e-53 181.3 0.0 2.8e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MMR_HSR1 PF01926.18 EIW69909.1 - 3.8e-16 59.0 0.1 1.3e-14 54.0 0.0 2.9 3 1 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW69909.1 - 1.3e-06 27.7 0.0 2.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EIW69909.1 - 5.1e-06 25.7 0.1 1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIW69909.1 - 6e-05 22.2 0.0 0.00018 20.7 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 EIW69909.1 - 0.00048 19.9 2.4 0.0017 18.1 0.1 2.6 2 1 1 3 3 3 1 Dynamin family Miro PF08477.8 EIW69909.1 - 0.0011 19.4 0.1 0.0035 17.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 EIW69909.1 - 0.063 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EIW69909.1 - 0.099 11.7 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin GTP_EFTU PF00009.22 EIW69909.1 - 0.12 11.8 0.1 2.8 7.3 0.0 2.6 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain OHCU_decarbox PF09349.5 EIW69910.1 - 1.8e-32 112.8 0.0 2.3e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase DUF4559 PF15112.1 EIW69911.1 - 0.018 14.2 1.8 0.022 13.9 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) cobW PF02492.14 EIW69912.1 - 2.2e-35 121.7 0.0 2.7e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EIW69912.1 - 4.9e-07 28.7 0.2 8.1e-06 24.8 0.1 2.0 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 EIW69912.1 - 0.0041 17.0 0.0 0.0088 15.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW69912.1 - 0.012 15.0 0.0 0.97 8.8 0.0 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Pox_A32 PF04665.7 EIW69912.1 - 0.022 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_18 PF13238.1 EIW69912.1 - 0.029 14.6 0.0 0.049 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW69912.1 - 0.031 15.0 0.2 0.053 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EIW69912.1 - 0.053 12.2 0.0 0.063 11.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 EIW69912.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EIW69912.1 - 0.12 12.3 0.1 0.5 10.3 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EIW69912.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Sin_N PF04801.8 EIW69913.1 - 7.8e-23 81.0 0.2 2.7e-21 75.9 0.2 2.0 1 1 0 1 1 1 1 Sin-like protein conserved region Helicase_C_3 PF13625.1 EIW69914.1 - 1e-26 93.1 0.0 3.1e-26 91.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW69914.1 - 5.8e-14 52.3 0.0 1.1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIW69914.1 - 2.8e-11 43.1 0.0 7.4e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIW69914.1 - 6.6e-10 38.2 0.0 1.1e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EIW69914.1 - 4.5e-06 26.2 0.1 1.2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF3421 PF11901.3 EIW69915.1 - 5.3e-29 100.3 0.3 1.6e-24 85.8 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) CBM_5_12 PF02839.9 EIW69915.1 - 0.019 14.5 0.6 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain DLH PF01738.13 EIW69917.1 - 6.5e-21 74.6 0.0 8.8e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW69917.1 - 0.0015 18.3 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIW69917.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2305 PF10230.4 EIW69917.1 - 0.066 12.6 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PAT1 PF09770.4 EIW69918.1 - 1.1e-148 496.9 0.0 1.7e-147 493.0 0.0 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 RhoGAP PF00620.22 EIW69920.1 - 5.3e-23 81.3 0.0 9.3e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 EIW69920.1 - 1.4e-21 76.6 0.0 2.4e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.21 EIW69920.1 - 3.5e-07 29.9 6.7 1.2e-05 25.0 4.1 2.5 2 0 0 2 2 2 1 WW domain Amdo_NSP PF12475.3 EIW69920.1 - 0.044 13.6 0.0 0.6 10.0 0.0 2.7 3 0 0 3 3 3 0 Amdovirus non-structural protein PPR_3 PF13812.1 EIW69921.1 - 1.4e-12 46.7 0.1 0.0021 18.1 0.0 7.0 7 0 0 7 7 7 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 EIW69921.1 - 1e-05 25.3 0.0 0.0023 17.8 0.0 4.3 4 1 3 7 7 7 3 PPR repeat family PPR PF01535.15 EIW69921.1 - 0.0019 18.0 2.1 14 5.9 0.1 6.2 6 2 0 6 6 6 1 PPR repeat FA_desaturase PF00487.19 EIW69922.1 - 1.7e-30 106.3 13.3 2.9e-30 105.5 9.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EIW69922.1 - 1.7e-17 62.3 0.2 3.4e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Ribosomal_L30_N PF08079.7 EIW69925.1 - 3.4e-24 84.6 10.5 6.6e-24 83.7 7.3 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EIW69925.1 - 6.6e-18 64.0 1.7 1.3e-17 63.0 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_60s PF00428.14 EIW69926.1 - 4.9e-24 84.5 7.8 6.1e-24 84.2 5.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ParBc PF02195.13 EIW69927.1 - 2e-08 34.1 0.0 4.9e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 ParB-like nuclease domain Bromodomain PF00439.20 EIW69929.1 - 7.5e-42 141.1 4.8 1.3e-21 76.3 0.1 2.3 2 0 0 2 2 2 2 Bromodomain SpoVG PF04026.7 EIW69929.1 - 0.013 15.5 0.1 7.2 6.7 0.0 2.7 2 0 0 2 2 2 0 SpoVG Hist_deacetyl PF00850.14 EIW69930.1 - 5.6e-50 170.3 0.0 8.3e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Tbf5 PF06331.7 EIW69931.1 - 7.6e-16 57.6 0.7 8.6e-16 57.4 0.5 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF410 PF04190.8 EIW69932.1 - 1.6e-18 67.2 0.0 2.2e-16 60.1 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF410) Ribosomal_S17 PF00366.15 EIW69933.1 - 3.8e-29 100.5 0.7 3.8e-29 100.5 0.5 1.5 2 0 0 2 2 2 1 Ribosomal protein S17 Tcf25 PF04910.9 EIW69934.1 - 9.8e-88 294.5 0.0 1.3e-87 294.1 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 RsmJ PF04378.8 EIW69934.1 - 0.053 12.5 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA small subunit methyltransferase D, RsmJ PRA1 PF03208.14 EIW69935.1 - 2.7e-38 130.7 0.0 3.1e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 PRA1 family protein VPS28 PF03997.7 EIW69936.1 - 1.6e-60 203.9 0.0 1.8e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Peptidase_C65 PF10275.4 EIW69936.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase C65 Otubain SAD_SRA PF02182.12 EIW69937.1 - 8.7e-37 125.8 0.0 1e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 SAD/SRA domain Cellulase PF00150.13 EIW69938.1 - 1.8e-12 47.0 0.1 1.4e-08 34.2 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) RibD_C PF01872.12 EIW69939.1 - 5.3e-16 58.8 0.0 6.5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain WD40 PF00400.27 EIW69940.1 - 9.9e-27 91.8 3.5 2.7e-11 42.8 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 EIW69940.1 - 1.7e-23 82.4 3.8 2.9e-23 81.6 2.7 1.4 1 0 0 1 1 1 1 Sof1-like domain LAMTOR PF15454.1 EIW69941.1 - 0.11 12.8 0.5 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Aminotran_3 PF00202.16 EIW69942.1 - 3e-87 292.6 0.0 4.1e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III KH_1 PF00013.24 EIW69943.1 - 1.3e-38 130.3 5.3 3.1e-10 39.5 0.0 9.4 9 0 0 9 9 9 8 KH domain KH_3 PF13014.1 EIW69943.1 - 3.3e-32 109.5 5.1 6.1e-08 32.1 0.1 7.0 7 0 0 7 7 7 6 KH domain Trp_syntA PF00290.15 EIW69944.1 - 3.9e-86 287.7 3.6 5.2e-86 287.3 0.1 2.1 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 EIW69944.1 - 3.5e-45 154.5 0.4 6e-45 153.7 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 EIW69944.1 - 0.00081 18.7 0.0 0.0021 17.4 0.0 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.12 EIW69944.1 - 0.1 11.8 0.1 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 PcrB family Rsa3 PF14615.1 EIW69945.1 - 4.1e-10 38.7 0.0 5.7e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 SR-25 PF10500.4 EIW69945.1 - 1 8.7 9.9 1.5 8.2 6.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nop14 PF04147.7 EIW69945.1 - 3.4 5.4 6.6 3.9 5.2 4.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF605 PF04652.11 EIW69945.1 - 5.8 6.1 10.9 7.1 5.9 7.6 1.1 1 0 0 1 1 1 0 Vta1 like Zn_clus PF00172.13 EIW69946.1 - 3.3e-09 36.5 8.2 5.2e-09 35.8 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EIW69948.1 - 3.9e-70 235.9 0.0 4.8e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_23 PF13489.1 EIW69949.1 - 2.9e-15 56.3 0.1 4.9e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW69949.1 - 7.8e-10 38.5 0.0 2.6e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW69949.1 - 9.6e-10 38.8 0.0 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW69949.1 - 1.3e-09 38.4 0.0 3.3e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW69949.1 - 7.7e-08 32.9 0.1 2.3e-06 28.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW69949.1 - 4.4e-07 30.1 0.0 3.4e-06 27.3 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW69949.1 - 7.6e-07 28.4 0.0 5.3e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EIW69949.1 - 3.7e-06 26.3 0.0 6.5e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase FtsJ PF01728.14 EIW69949.1 - 7.1e-05 22.8 0.0 0.00034 20.6 0.0 2.3 2 1 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 EIW69949.1 - 0.00017 21.0 0.0 0.0012 18.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIW69949.1 - 0.00019 21.4 0.0 0.0018 18.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIW69949.1 - 0.032 13.3 0.0 0.12 11.4 0.0 2.0 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EIW69949.1 - 0.038 13.0 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase SKG6 PF08693.5 EIW69951.1 - 0.006 15.8 0.1 0.018 14.3 0.0 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 EIW69951.1 - 0.009 15.4 0.0 0.009 15.4 0.0 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 EIW69951.1 - 0.17 10.1 0.0 0.17 10.1 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E RCR PF12273.3 EIW69951.1 - 0.26 11.8 0.0 0.26 11.8 0.0 3.1 3 1 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red Adeno_E3_CR2 PF02439.10 EIW69951.1 - 0.28 10.7 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Beta-APP PF03494.8 EIW69951.1 - 0.43 10.0 3.0 0.81 9.2 2.1 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) UBA PF00627.26 EIW69954.1 - 3e-22 77.7 5.6 1e-12 47.4 0.0 2.8 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.6 EIW69954.1 - 2.5e-21 74.8 1.7 4.6e-21 74.0 1.2 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EIW69954.1 - 1.8e-19 68.8 1.7 2.8e-19 68.2 1.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIW69954.1 - 2.3e-07 30.4 2.8 3.6e-07 29.7 2.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EIW69954.1 - 8.1e-05 22.1 0.0 0.059 12.9 0.0 2.5 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain CUE PF02845.11 EIW69954.1 - 0.006 16.0 0.2 0.07 12.6 0.0 2.5 3 0 0 3 3 3 1 CUE domain Rad60-SLD_2 PF13881.1 EIW69954.1 - 0.04 13.8 0.1 0.085 12.7 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like WIYLD PF10440.4 EIW69954.1 - 0.12 12.3 0.0 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Rap1_C PF11626.3 EIW69954.1 - 0.13 12.1 0.0 7.1 6.6 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ubiquitin_2 PF14560.1 EIW69954.1 - 0.23 11.7 1.4 1.5 9.0 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_L29 PF00831.18 EIW69955.1 - 4.2e-19 67.9 1.7 4.2e-19 67.9 1.2 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EIW69955.1 - 0.0039 17.4 2.0 0.0049 17.0 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Transcrip_act PF04949.8 EIW69955.1 - 0.026 14.1 1.2 0.032 13.8 0.1 1.7 1 1 0 1 1 1 0 Transcriptional activator Translin PF01997.11 EIW69955.1 - 0.049 13.2 1.0 0.085 12.4 0.7 1.5 1 1 0 1 1 1 0 Translin family Ribosomal_L27e PF01777.13 EIW69957.1 - 9.7e-37 124.9 3.6 1.2e-36 124.6 2.5 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EIW69957.1 - 4.7e-06 26.0 0.2 1.1e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 KOW motif ATG13 PF10033.4 EIW69958.1 - 1.7e-36 125.7 0.0 2.6e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 RNA_pol_I_TF PF04090.7 EIW69960.1 - 1.4e-07 31.0 1.1 0.00012 21.3 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TPR_14 PF13428.1 EIW69960.1 - 0.065 13.9 1.8 19 6.2 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat NHR2 PF08788.6 EIW69960.1 - 0.96 8.9 3.4 0.26 10.7 0.3 1.6 2 0 0 2 2 2 0 NHR2 domain like TPR_4 PF07721.9 EIW69960.1 - 1.5 9.4 11.7 1.1 9.9 0.4 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.24 EIW69961.1 - 1.1e-44 151.8 1.5 2.6e-44 150.7 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW69961.1 - 4.8e-28 96.8 0.2 2e-27 94.8 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EIW69961.1 - 0.0015 18.2 0.2 0.0038 16.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EIW69961.1 - 0.0052 16.6 0.1 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA-synt_1b PF00579.20 EIW69961.1 - 0.012 14.6 0.1 0.046 12.8 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_30 PF13604.1 EIW69961.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EIW69961.1 - 0.042 13.1 0.2 0.078 12.2 0.1 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.9 EIW69961.1 - 0.048 13.4 0.2 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain DUF1253 PF06862.7 EIW69961.1 - 0.08 11.3 0.0 5.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 EIW69961.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain Helicase_RecD PF05127.9 EIW69961.1 - 0.09 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Helicase DUF2346 PF09803.4 EIW69962.1 - 7.4e-08 32.1 0.5 1.1e-07 31.5 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) ABC_membrane PF00664.18 EIW69963.1 - 1.8e-50 171.9 26.3 5.4e-24 85.0 2.6 3.9 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.22 EIW69963.1 - 3e-48 163.6 0.0 2.8e-28 98.9 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIW69963.1 - 2.5e-08 33.4 1.8 0.00042 19.6 0.3 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW69963.1 - 8.6e-07 29.1 2.2 1.9 8.3 0.0 4.7 4 1 0 5 5 5 2 AAA domain AAA_25 PF13481.1 EIW69963.1 - 1.4e-06 27.8 0.2 0.014 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW69963.1 - 2.8e-05 23.5 3.0 0.082 12.4 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EIW69963.1 - 3e-05 23.0 2.8 0.062 12.1 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EIW69963.1 - 3.3e-05 23.9 0.0 0.12 12.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EIW69963.1 - 6.9e-05 23.2 1.3 0.0093 16.3 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIW69963.1 - 0.00012 22.1 0.2 2.7 8.1 0.1 3.6 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EIW69963.1 - 0.00036 20.0 0.3 0.33 10.3 0.1 2.6 2 1 0 2 2 2 2 AAA-like domain AAA_19 PF13245.1 EIW69963.1 - 0.0044 16.7 3.9 0.02 14.6 0.1 3.7 4 0 0 4 4 2 1 Part of AAA domain AAA_18 PF13238.1 EIW69963.1 - 0.0051 17.1 0.3 4 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EIW69963.1 - 0.0054 17.5 2.1 0.81 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIW69963.1 - 0.014 15.1 0.1 0.71 9.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Zot PF05707.7 EIW69963.1 - 0.049 13.1 0.0 5.4 6.4 0.0 2.7 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) ATP-synt_ab PF00006.20 EIW69963.1 - 0.053 13.0 0.2 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 EIW69963.1 - 0.055 13.3 0.0 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EIW69963.1 - 0.056 12.8 1.5 2.5 7.4 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EIW69963.1 - 0.075 12.7 1.2 4.9 6.8 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EIW69963.1 - 0.078 12.6 1.5 11 5.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 EIW69963.1 - 0.081 12.0 0.6 7 5.6 0.3 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 EIW69963.1 - 0.1 12.3 1.7 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA PF00004.24 EIW69963.1 - 0.14 12.3 0.1 41 4.3 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EIW69963.1 - 0.15 11.0 0.1 0.54 9.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EIW69963.1 - 0.24 10.8 1.0 6.3 6.2 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase ResIII PF04851.10 EIW69963.1 - 0.69 9.7 1.6 31 4.3 0.3 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 EIW69963.1 - 0.82 8.2 3.5 6.1 5.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain HLH PF00010.21 EIW69965.1 - 4.5e-12 45.4 0.3 4.5e-12 45.4 0.2 3.8 3 1 0 3 3 3 1 Helix-loop-helix DNA-binding domain CAF-1_p150 PF11600.3 EIW69965.1 - 0.0043 16.4 17.7 0.0043 16.4 12.3 2.5 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hex_IIIa PF02455.11 EIW69965.1 - 0.75 8.4 4.0 0.97 8.0 2.8 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) UIM PF02809.15 EIW69966.1 - 0.18 11.4 4.1 0.43 10.2 2.8 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Pkinase PF00069.20 EIW69968.1 - 4.5e-54 183.3 0.0 5.2e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69968.1 - 4.8e-37 127.4 0.0 6.1e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW69968.1 - 3.7e-07 29.4 0.0 5.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW69968.1 - 0.033 13.9 0.0 0.084 12.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family CIA30 PF08547.7 EIW69969.1 - 5.5e-16 58.8 0.0 1.6e-15 57.2 0.0 1.8 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.16 EIW69970.1 - 1.9e-11 43.7 3.0 4.5e-11 42.5 2.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIW69970.1 - 6.4e-08 32.2 8.0 6.4e-08 32.2 5.6 2.4 2 1 1 3 3 3 2 Basic region leucine zipper DUF4200 PF13863.1 EIW69970.1 - 0.0065 16.4 1.1 0.0065 16.4 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) ATP-synt_B PF00430.13 EIW69970.1 - 2.5 7.9 9.5 0.47 10.2 2.4 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Sec7_N PF12783.2 EIW69971.1 - 7e-27 93.9 0.0 4.6e-26 91.2 0.0 2.4 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EIW69971.1 - 0.0004 19.8 0.0 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) MutS_V PF00488.16 EIW69972.1 - 4.3e-99 330.6 0.2 1.7e-98 328.7 0.0 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EIW69972.1 - 4.8e-31 108.1 1.5 1e-30 107.0 1.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EIW69972.1 - 1e-16 60.8 0.5 2.6e-16 59.5 0.4 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EIW69972.1 - 6.1e-14 52.2 0.0 1.7e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 EIW69972.1 - 6.9e-10 38.9 0.0 9.4e-09 35.3 0.0 2.5 1 1 0 1 1 1 1 MutS domain I UTP15_C PF09384.5 EIW69973.1 - 2.2e-47 160.4 0.0 3.5e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EIW69973.1 - 4.2e-33 112.0 8.0 5.8e-08 32.3 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIW69973.1 - 0.00022 19.5 0.0 0.00055 18.2 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIW69973.1 - 0.016 13.4 0.0 2.3 6.4 0.0 2.5 2 1 1 3 3 3 0 Cytochrome D1 heme domain PQQ_2 PF13360.1 EIW69973.1 - 0.028 13.8 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain 2-Hacid_dh_C PF02826.14 EIW69974.1 - 2.7e-48 163.4 0.0 4.8e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW69974.1 - 1e-33 115.6 0.0 1.3e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EIW69974.1 - 0.00025 20.9 0.0 0.0027 17.5 0.0 2.2 1 1 1 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 EIW69974.1 - 0.0029 17.0 0.0 0.007 15.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.10 EIW69974.1 - 0.011 15.5 0.1 0.031 14.1 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1192 PF06698.6 EIW69975.1 - 0.058 13.2 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Myb_DNA-bind_4 PF13837.1 EIW69976.1 - 0.0008 19.4 0.2 0.0026 17.8 0.1 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Pkinase PF00069.20 EIW69977.1 - 5.3e-49 166.7 0.0 2.5e-48 164.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW69977.1 - 1.4e-37 129.2 0.0 8.4e-21 74.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW69977.1 - 0.00047 19.2 0.0 0.02 13.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like NTPase_I-T PF01931.13 EIW69977.1 - 0.042 13.5 0.2 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF84 LSM PF01423.17 EIW69978.1 - 1.7e-16 59.5 0.0 2.1e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain RNA_pol_Rpb5_C PF01191.14 EIW69979.1 - 3.5e-34 116.2 0.5 6.2e-34 115.4 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EIW69979.1 - 1.1e-26 93.0 0.2 2.3e-26 92.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EIW69979.1 - 0.0061 16.3 0.0 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 Restriction endonuclease Transp_cyt_pur PF02133.10 EIW69982.1 - 3.4e-31 108.2 36.8 4.7e-31 107.8 25.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Complex1_LYR PF05347.10 EIW69983.1 - 2.4e-07 30.4 0.0 4.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIW69983.1 - 8e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EIW69983.1 - 0.00063 20.1 0.0 0.0008 19.8 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like RPEL PF02755.10 EIW69984.1 - 0.04 13.2 0.2 0.093 12.0 0.1 1.7 1 0 0 1 1 1 0 RPEL repeat CN_hydrolase PF00795.17 EIW69986.1 - 1.7e-23 82.9 0.0 2.5e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_S24 PF00717.18 EIW69987.1 - 0.00013 21.5 0.0 0.00089 18.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EIW69987.1 - 0.00072 19.0 0.0 0.015 14.8 0.0 2.5 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_M24 PF00557.19 EIW69988.1 - 4.4e-42 144.0 0.2 5.5e-42 143.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EIW69988.1 - 9.2e-06 25.4 5.6 2.2e-05 24.2 3.9 1.7 1 0 0 1 1 1 1 MYND finger BolA PF01722.13 EIW69989.1 - 1.9e-14 53.3 0.0 2.1e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 BolA-like protein Adaptin_N PF01602.15 EIW69990.1 - 6.4e-135 450.4 0.3 7.8e-135 450.1 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EIW69990.1 - 2.5e-20 73.0 0.0 1.7e-18 67.1 0.0 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EIW69990.1 - 2e-12 47.2 6.8 0.00023 21.3 0.0 4.9 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.17 EIW69990.1 - 7e-06 25.6 1.2 0.77 10.0 0.0 4.7 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 EIW69990.1 - 2.8e-05 23.7 0.1 0.016 15.0 0.0 4.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EIW69990.1 - 0.005 16.5 0.0 0.035 13.8 0.0 2.4 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Proteasom_PSMB PF10508.4 EIW69990.1 - 0.009 14.3 0.0 0.11 10.6 0.0 2.3 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 EIW69990.1 - 0.019 14.2 0.0 5 6.4 0.0 2.7 2 0 0 2 2 2 0 CLASP N terminal HEAT_EZ PF13513.1 EIW69990.1 - 0.024 15.1 5.0 3.3 8.3 0.0 4.9 4 1 1 5 5 5 0 HEAT-like repeat Cnd3 PF12719.2 EIW69990.1 - 0.042 12.8 0.0 0.097 11.6 0.0 1.6 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain TPT PF03151.11 EIW69991.1 - 4.1e-29 101.1 12.9 4.1e-29 101.1 8.9 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EIW69991.1 - 2.9e-07 29.7 18.8 5e-07 28.9 13.0 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIW69991.1 - 0.00063 19.7 30.0 0.036 14.1 6.3 2.5 2 1 0 2 2 2 2 EamA-like transporter family RRF PF01765.14 EIW69992.1 - 1.8e-27 95.7 0.4 4e-27 94.6 0.0 1.7 2 1 0 2 2 2 1 Ribosome recycling factor zf-CCHC PF00098.18 EIW69993.1 - 1.5e-13 49.9 21.4 0.00024 20.8 0.7 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EIW69993.1 - 5.6e-05 22.7 17.3 0.19 11.4 0.5 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 EIW69993.1 - 0.0056 16.1 12.3 0.033 13.6 1.6 3.7 3 1 1 4 4 4 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW69993.1 - 0.16 11.6 0.3 0.16 11.6 0.2 4.1 2 1 2 4 4 4 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIW69993.1 - 5.2 6.6 17.2 1.1 8.8 0.4 3.7 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Y_phosphatase2 PF03162.8 EIW69994.1 - 8.4e-45 152.0 0.0 1.5e-44 151.2 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EIW69994.1 - 0.00012 22.3 0.0 0.0013 19.0 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EIW69994.1 - 0.0072 15.9 0.0 0.073 12.6 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myb_DNA-bind_4 PF13837.1 EIW69995.1 - 0.0016 18.4 0.2 0.0051 16.9 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CD99L2 PF12301.3 EIW69995.1 - 0.21 11.2 3.7 0.48 10.1 2.6 1.7 1 1 0 1 1 1 0 CD99 antigen like protein 2 DUF3820 PF12843.2 EIW69998.1 - 0.031 13.9 0.1 0.075 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3820) Ashwin PF15323.1 EIW69999.1 - 0.039 13.9 3.8 0.054 13.4 2.6 1.2 1 0 0 1 1 1 0 Developmental protein SR-25 PF10500.4 EIW69999.1 - 0.12 11.8 16.2 0.22 10.9 11.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.5 EIW69999.1 - 0.71 8.8 3.8 0.95 8.4 2.7 1.1 1 0 0 1 1 1 0 BUD22 Sua5_yciO_yrdC PF01300.13 EIW70001.1 - 1.7e-44 151.2 0.0 2.5e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EIW70001.1 - 2.4e-19 69.6 0.0 4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Nop25 PF09805.4 EIW70002.1 - 1.9e-17 63.6 22.8 1.9e-17 63.6 15.8 2.3 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Hid1 PF12722.2 EIW70002.1 - 6.1 4.3 9.1 8.9 3.8 6.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PEX11 PF05648.9 EIW70002.1 - 9.1 5.4 6.6 2.1 7.5 0.3 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) AA_permease_2 PF13520.1 EIW70003.1 - 6.4e-60 202.8 35.4 8.1e-60 202.5 24.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW70003.1 - 1.9e-28 99.0 32.8 3.6e-28 98.1 22.7 1.4 1 1 0 1 1 1 1 Amino acid permease Rep_fac_C PF08542.6 EIW70004.1 - 5.5e-24 83.9 0.2 1.4e-23 82.6 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EIW70004.1 - 2.9e-12 46.5 0.0 6.4e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EIW70004.1 - 2.4e-05 24.5 0.3 6.6e-05 23.1 0.2 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 EIW70004.1 - 0.00024 20.6 0.1 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit SNF2_N PF00176.18 EIW70004.1 - 0.00061 18.6 0.2 0.0011 17.7 0.0 1.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EIW70004.1 - 0.0015 18.6 1.0 0.01 15.9 0.3 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIW70004.1 - 0.0025 16.9 0.2 1.9 7.4 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EIW70004.1 - 0.0047 15.6 0.0 0.0067 15.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EIW70004.1 - 0.013 14.9 0.1 0.82 9.0 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 EIW70004.1 - 0.016 14.8 0.0 0.072 12.7 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 EIW70004.1 - 0.017 14.9 0.0 0.048 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3802 PF12290.3 EIW70004.1 - 0.024 14.9 0.4 0.058 13.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) AAA_16 PF13191.1 EIW70004.1 - 0.035 14.0 0.4 0.24 11.3 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 EIW70004.1 - 0.045 13.8 0.1 0.59 10.1 0.1 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Hydrolase_6 PF13344.1 EIW70005.1 - 1.4e-30 105.1 0.0 2.6e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW70005.1 - 2.9e-17 62.1 0.0 7.8e-17 60.7 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EIW70005.1 - 8e-13 49.2 0.0 1.8e-12 48.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIW70005.1 - 6.1e-09 36.3 0.0 0.00086 19.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PAN_1 PF00024.21 EIW70005.1 - 0.013 15.2 0.2 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 PAN domain Ribosomal_L7Ae PF01248.21 EIW70005.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PGA2 PF07543.7 EIW70006.1 - 0.17 11.6 2.9 0.67 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF3245 PF11595.3 EIW70006.1 - 0.97 9.6 7.1 0.12 12.6 0.8 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3245) NTS PF15447.1 EIW70010.1 - 0.11 12.8 0.2 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 F-actin_cap_A PF01267.12 EIW70011.1 - 1.6e-63 214.3 0.6 2e-63 214.0 0.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit APG5 PF04106.7 EIW70011.1 - 0.09 12.2 0.8 0.17 11.3 0.2 1.7 2 0 0 2 2 2 0 Autophagy protein Apg5 SH2_2 PF14633.1 EIW70012.1 - 4.1e-67 225.4 0.1 4.1e-67 225.4 0.1 1.9 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 EIW70012.1 - 7.6e-28 96.9 0.1 3.7e-27 94.7 0.1 2.3 1 0 0 1 1 1 1 Death-like domain of SPT6 YqgF PF14639.1 EIW70012.1 - 3.4e-21 75.3 0.8 3.2e-09 36.5 0.0 2.8 1 1 0 2 2 2 2 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 EIW70012.1 - 2.5e-18 66.0 0.0 5.9e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 EIW70012.1 - 1.5e-15 57.0 12.9 1.5e-15 57.0 9.0 3.6 4 0 0 4 4 4 2 Acidic N-terminal SPT6 HTH_44 PF14641.1 EIW70012.1 - 8e-10 38.7 0.1 2.1e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EIW70012.1 - 0.00022 20.9 0.0 0.00055 19.6 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Cytomega_UL20A PF05984.7 EIW70012.1 - 3.6 7.8 7.1 15 5.8 0.4 2.7 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Porin_3 PF01459.17 EIW70013.1 - 2.3e-69 233.7 0.1 2.7e-69 233.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Tho2 PF11262.3 EIW70014.1 - 1.3e-68 231.2 0.0 1.3e-68 231.2 0.0 1.6 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EIW70014.1 - 1.4e-22 79.2 0.0 3.1e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit PI-PLC-X PF00388.14 EIW70015.1 - 8e-54 181.0 0.0 3.9e-53 178.7 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EIW70015.1 - 5.5e-36 123.1 0.0 9.7e-36 122.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EIW70015.1 - 1.1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Peptidase_M1 PF01433.15 EIW70016.1 - 9.8e-102 340.9 0.0 3.7e-71 240.2 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 EIW70016.1 - 2.2e-65 221.0 0.0 2.9e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EIW70016.1 - 8.5e-14 51.6 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily GTP_cyclohydroI PF01227.17 EIW70017.1 - 3.1e-73 244.8 0.2 4.2e-73 244.4 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EIW70017.1 - 0.0035 17.2 0.0 0.0096 15.8 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 EIW70017.1 - 0.052 13.3 0.2 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Ribosomal_L37ae PF01780.14 EIW70018.1 - 3.5e-41 138.9 8.7 3.9e-41 138.8 6.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EIW70018.1 - 0.00024 20.8 3.1 0.00035 20.3 2.1 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIW70018.1 - 0.012 15.5 3.0 0.03 14.2 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain NOB1_Zn_bind PF08772.6 EIW70018.1 - 0.018 14.8 3.2 0.032 14.0 0.7 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-H2C2_2 PF13465.1 EIW70018.1 - 0.018 15.3 4.7 0.51 10.7 0.7 2.4 1 1 1 2 2 2 0 Zinc-finger double domain OrfB_Zn_ribbon PF07282.6 EIW70018.1 - 0.041 13.5 1.2 0.059 13.0 0.8 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Elf1 PF05129.8 EIW70018.1 - 0.083 12.5 2.0 0.15 11.8 1.4 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Terminase_GpA PF05876.7 EIW70018.1 - 0.091 11.1 0.2 0.094 11.0 0.1 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF1610 PF07754.6 EIW70018.1 - 0.13 12.4 0.4 0.13 12.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-ribbon_3 PF13248.1 EIW70018.1 - 0.14 11.4 1.6 0.2 10.9 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.1 EIW70018.1 - 0.24 11.8 1.1 4.7 7.7 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EIW70018.1 - 0.31 10.8 3.1 1.7 8.4 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger zf-HIT PF04438.11 EIW70018.1 - 0.55 9.9 3.5 0.42 10.3 0.4 2.0 2 0 0 2 2 2 0 HIT zinc finger Rep_fac-A_C PF08646.5 EIW70018.1 - 0.66 9.6 2.7 1.3 8.7 1.9 1.5 1 1 0 1 1 1 0 Replication factor-A C terminal domain zf-TFIIB PF13453.1 EIW70018.1 - 0.77 8.9 3.3 3.8 6.7 2.3 1.9 1 1 1 2 2 2 0 Transcription factor zinc-finger DUF4606 PF15379.1 EIW70018.1 - 1.5 8.9 4.5 0.34 10.9 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) Mut7-C PF01927.11 EIW70018.1 - 2 8.4 4.2 19 5.2 2.9 2.0 1 1 0 1 1 1 0 Mut7-C RNAse domain zf-C2H2 PF00096.21 EIW70018.1 - 2 8.9 4.6 2.9 8.4 0.2 2.6 2 1 0 2 2 2 0 Zinc finger, C2H2 type Ion_trans_2 PF07885.11 EIW70019.1 - 2.3e-17 62.4 29.4 2e-10 40.2 3.2 3.5 3 1 0 3 3 3 2 Ion channel DUF1980 PF09323.5 EIW70019.1 - 4.1 7.0 9.4 0.57 9.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Zn_clus PF00172.13 EIW70020.1 - 2e-07 30.7 10.2 4.5e-07 29.6 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIW70020.1 - 5.1e-05 22.2 0.0 7.3e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SQS_PSY PF00494.14 EIW70021.1 - 2.1e-37 128.9 0.0 1.3e-18 67.2 0.0 2.2 2 0 0 2 2 2 2 Squalene/phytoene synthase bZIP_1 PF00170.16 EIW70022.1 - 1.9e-08 34.1 8.1 1.9e-08 34.1 5.6 2.2 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EIW70022.1 - 4.7e-07 29.5 11.9 4.7e-07 29.5 8.2 3.0 3 0 0 3 3 3 1 Basic region leucine zipper Macoilin PF09726.4 EIW70022.1 - 0.0011 17.4 9.5 0.0019 16.5 6.6 1.3 1 0 0 1 1 1 1 Transmembrane protein TSC22 PF01166.13 EIW70022.1 - 0.12 12.3 1.8 0.67 9.9 0.3 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF4407 PF14362.1 EIW70022.1 - 0.5 9.2 3.5 1.1 8.0 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DTHCT PF08070.6 EIW70022.1 - 0.58 10.8 14.3 3.5 8.3 3.7 2.7 2 0 0 2 2 2 0 DTHCT (NUC029) region IncA PF04156.9 EIW70022.1 - 0.69 9.4 7.7 1.8 8.1 5.4 1.6 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EIW70022.1 - 4.1 5.1 5.2 6.2 4.5 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1242 PF06842.7 EIW70023.1 - 3.5e-16 58.4 0.6 4.5e-16 58.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Rad17 PF03215.10 EIW70024.1 - 8.7e-44 150.0 0.0 9e-43 146.7 0.0 1.9 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EIW70024.1 - 9.5e-05 22.6 0.0 0.00021 21.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW70024.1 - 0.00034 21.4 0.0 0.00034 21.4 0.0 2.2 3 1 0 3 3 1 1 AAA domain AAA_22 PF13401.1 EIW70024.1 - 0.0004 20.5 0.0 0.0009 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW70024.1 - 0.00083 19.0 0.0 0.0026 17.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain UPF0079 PF02367.12 EIW70024.1 - 0.0023 17.5 0.0 0.0056 16.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EIW70024.1 - 0.0024 17.8 0.9 0.0047 16.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIW70024.1 - 0.0027 16.7 0.0 0.0057 15.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EIW70024.1 - 0.0032 16.5 0.1 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EIW70024.1 - 0.0042 17.0 0.0 0.037 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EIW70024.1 - 0.0042 17.3 0.1 0.0042 17.3 0.1 1.9 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 EIW70024.1 - 0.01 15.4 0.1 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EIW70024.1 - 0.011 14.7 0.0 0.035 13.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 EIW70024.1 - 0.017 15.3 0.1 0.054 13.7 0.1 1.8 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EIW70024.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW70024.1 - 0.034 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Herpes_Helicase PF02689.9 EIW70024.1 - 0.068 10.9 0.0 0.11 10.2 0.0 1.2 1 0 0 1 1 1 0 Helicase SRP54 PF00448.17 EIW70024.1 - 0.072 12.5 0.3 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Ribosomal_L19 PF01245.15 EIW70024.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L19 AAA_14 PF13173.1 EIW70024.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.6 EIW70024.1 - 0.18 10.4 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Peptidase_M13_N PF05649.8 EIW70025.1 - 1.1e-94 317.6 0.0 1.4e-94 317.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EIW70025.1 - 1.6e-58 197.3 0.0 2e-57 193.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_MA_2 PF13485.1 EIW70025.1 - 0.09 12.8 1.1 0.26 11.3 0.8 1.8 1 1 0 1 1 1 0 Peptidase MA superfamily Ytp1 PF10355.4 EIW70026.1 - 1e-74 251.1 17.5 1e-74 251.1 12.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EIW70026.1 - 5.5e-20 70.8 12.9 1.1e-12 47.4 0.4 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) DUF962 PF06127.6 EIW70026.1 - 0.034 14.0 2.2 0.21 11.4 0.1 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF962) MMgT PF10270.4 EIW70026.1 - 0.095 13.1 0.3 0.35 11.3 0.1 2.0 2 0 0 2 2 2 0 Membrane magnesium transporter SAYSvFN PF10260.4 EIW70026.1 - 0.79 9.5 4.2 5.3 6.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) zf-C2HC_2 PF13913.1 EIW70027.1 - 0.003 17.1 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.1 EIW70027.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIW70027.1 - 0.025 14.1 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-FCS PF06467.9 EIW70028.1 - 0.13 11.9 0.3 0.13 11.9 0.2 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Nucleo_P87 PF07267.6 EIW70028.1 - 4.4 5.8 12.4 0.044 12.4 3.0 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 FAM195 PF14799.1 EIW70029.1 - 0.037 13.8 0.5 0.057 13.2 0.1 1.6 2 0 0 2 2 2 0 FAM195 family Ish1 PF10281.4 EIW70029.1 - 0.053 13.6 0.3 0.099 12.7 0.2 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein TRAM_LAG1_CLN8 PF03798.11 EIW70031.1 - 0.062 12.8 14.6 0.093 12.2 9.9 1.4 1 1 0 1 1 1 0 TLC domain Aminotran_1_2 PF00155.16 EIW70032.1 - 1.6e-78 264.2 0.0 2.1e-78 263.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EIW70032.1 - 1.2e-05 24.2 0.0 2.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EIW70032.1 - 6.4e-05 21.4 0.0 0.00011 20.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EIW70032.1 - 0.00011 21.4 0.2 0.00021 20.4 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pertussis_S1 PF02917.9 EIW70032.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 WD40 PF00400.27 EIW70033.1 - 4.3e-50 165.8 28.9 6.1e-07 29.0 0.1 12.2 13 0 0 13 13 13 10 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIW70033.1 - 0.029 14.1 0.1 3.9 7.2 0.0 4.0 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Prismane PF03063.15 EIW70034.1 - 0.078 11.3 0.0 0.097 11.0 0.0 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Mt_ATP-synt_D PF05873.7 EIW70037.1 - 2.9e-11 43.2 1.7 3.3e-11 43.0 1.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DivIC PF04977.10 EIW70037.1 - 0.092 12.2 0.3 0.092 12.2 0.2 1.9 3 0 0 3 3 3 0 Septum formation initiator DUF2765 PF10963.3 EIW70037.1 - 0.4 10.6 3.6 8.2 6.4 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2765) RRM_1 PF00076.17 EIW70038.1 - 2.5e-16 59.0 0.0 4.6e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW70038.1 - 5.6e-14 51.8 0.1 1.4e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW70038.1 - 4.7e-06 26.3 0.0 7.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.22 EIW70039.1 - 3.4e-10 40.1 0.0 1.1e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 PCI domain Ribosomal_L10 PF00466.15 EIW70040.1 - 0.00015 21.6 0.1 0.0097 15.8 0.0 2.7 3 0 0 3 3 3 2 Ribosomal protein L10 MCM PF00493.18 EIW70041.1 - 4.3e-137 456.3 0.2 7.9e-137 455.4 0.2 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIW70041.1 - 2.1e-22 79.8 0.0 6.9e-22 78.1 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIW70041.1 - 1.2e-07 31.1 0.0 1.9e-06 27.1 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Tir_receptor_M PF03549.9 EIW70041.1 - 0.00028 20.9 0.3 0.017 15.2 0.0 2.6 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) intimin-binding domain AAA_3 PF07726.6 EIW70041.1 - 0.0017 17.9 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW70041.1 - 0.0019 17.7 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EIW70041.1 - 0.0047 16.6 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TPD PF14811.1 EIW70041.1 - 0.021 14.3 0.7 1.2 8.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function TPD sequence-motif DnaJ PF00226.26 EIW70042.1 - 1.6e-21 75.7 2.0 2.8e-21 75.0 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIW70042.1 - 3.3e-21 74.9 0.2 6.9e-18 64.3 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIW70042.1 - 3.6e-15 55.7 17.9 6.2e-15 55.0 12.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EIW70042.1 - 0.049 13.3 11.8 0.24 11.0 1.9 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family PPP4R2 PF09184.6 EIW70043.1 - 1.7e-14 54.0 0.0 2.8e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 PPP4R2 DUF1682 PF07946.9 EIW70044.1 - 7.5e-52 176.1 0.0 8.8e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) MRP-S31 PF15433.1 EIW70044.1 - 0.15 11.4 7.3 0.18 11.1 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 MRP-S26 PF14943.1 EIW70044.1 - 0.41 10.1 13.9 0.56 9.7 9.6 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF3381 PF11861.3 EIW70044.1 - 4.1 6.8 16.9 5.7 6.4 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) NmrA PF05368.8 EIW70046.1 - 4.3e-43 147.2 0.0 6e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW70046.1 - 1.2e-12 48.2 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW70046.1 - 1.4e-06 27.9 0.0 4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW70046.1 - 2.3e-05 23.2 0.0 3.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EIW70046.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.12 EIW70046.1 - 0.013 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DDE_Tnp_4 PF13359.1 EIW70047.1 - 1.4e-13 50.7 0.0 2.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Sigma70_r4_2 PF08281.7 EIW70047.1 - 0.00054 19.3 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.1 EIW70047.1 - 0.00083 18.9 0.1 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_4 PF13613.1 EIW70047.1 - 0.002 17.6 0.1 0.004 16.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.1 EIW70047.1 - 0.0077 16.2 0.1 0.023 14.7 0.0 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIW70047.1 - 0.01 15.1 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.1 EIW70047.1 - 0.018 15.2 0.2 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.10 EIW70047.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase GerE PF00196.14 EIW70047.1 - 0.094 12.0 0.3 0.58 9.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family EBP50_C-term PF09007.6 EIW70048.1 - 0.11 12.4 0.8 0.3 10.9 0.6 1.7 1 0 0 1 1 1 0 EBP50, C-terminal NmrA PF05368.8 EIW70050.1 - 3.5e-24 85.3 0.0 5.2e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW70050.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW70050.1 - 0.012 14.3 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-CCHC PF00098.18 EIW70050.1 - 0.022 14.6 4.3 0.062 13.2 3.0 1.8 1 0 0 1 1 1 0 Zinc knuckle RNA_lig_T4_1 PF09511.5 EIW70050.1 - 0.024 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA ligase Resolvase PF00239.16 EIW70050.1 - 0.046 13.5 7.7 0.028 14.2 1.7 2.5 3 0 0 3 3 3 0 Resolvase, N terminal domain zf-CCHC_2 PF13696.1 EIW70050.1 - 0.054 13.0 0.2 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW70050.1 - 0.24 11.6 3.8 0.45 10.7 0.2 2.8 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Hemerythrin PF01814.18 EIW70051.1 - 0.00025 21.2 1.5 0.62 10.2 0.0 2.2 2 0 0 2 2 2 2 Hemerythrin HHE cation binding domain FMN_red PF03358.10 EIW70052.1 - 1.2e-07 31.4 0.0 2.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EIW70052.1 - 0.0026 17.7 0.8 0.0065 16.4 0.2 1.8 2 0 0 2 2 2 1 Flavodoxin SH3BGR PF04908.10 EIW70053.1 - 4.4e-07 29.7 0.1 1.6e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein DUF3140 PF11338.3 EIW70054.1 - 1.7e-25 88.9 1.7 1.7e-25 88.9 1.2 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3140) BOP1NT PF08145.7 EIW70055.1 - 4.3e-103 344.5 8.4 8.5e-103 343.6 5.8 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EIW70055.1 - 1.1e-29 101.1 5.7 4.7e-08 32.6 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Foamy_virus_ENV PF03408.9 EIW70055.1 - 0.38 8.2 0.0 0.54 7.7 0.0 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein Nop14 PF04147.7 EIW70056.1 - 2.2 6.1 8.1 1.9 6.3 0.4 2.3 2 0 0 2 2 2 0 Nop14-like family CENP-T PF15511.1 EIW70056.1 - 4.2 6.5 8.7 18 4.4 6.0 1.9 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Proteasome PF00227.21 EIW70057.1 - 1.1e-59 200.9 0.0 1.7e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW70057.1 - 3e-10 39.2 0.2 7.7e-10 37.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature STE3 PF02076.10 EIW70058.1 - 8.6e-63 212.0 9.8 1e-62 211.8 6.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor Rad60-SLD_2 PF13881.1 EIW70059.1 - 0.0029 17.4 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIW70059.1 - 0.0079 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EIW70059.1 - 0.066 13.4 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sporozoite_P67 PF05642.6 EIW70059.1 - 0.42 8.4 0.5 0.63 7.8 0.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ADIP PF11559.3 EIW70060.1 - 1.3e-22 80.3 1.5 1.3e-22 80.3 1.0 3.8 3 1 1 4 4 4 2 Afadin- and alpha -actinin-Binding IncA PF04156.9 EIW70060.1 - 0.0044 16.6 3.3 0.0044 16.6 2.3 2.5 2 1 0 2 2 2 1 IncA protein SRP54 PF00448.17 EIW70063.1 - 1.2e-47 161.9 0.5 7.9e-46 155.9 0.4 2.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EIW70063.1 - 1.1e-32 113.5 0.0 1.3e-21 77.2 0.0 2.1 1 1 0 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 EIW70063.1 - 2.6e-08 33.8 1.1 4.8e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EIW70063.1 - 1.6e-07 30.9 0.1 4.5e-07 29.4 0.1 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EIW70063.1 - 6.1e-06 25.2 0.1 2.8e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 ArgK protein MobB PF03205.9 EIW70063.1 - 0.0025 17.5 0.1 0.0086 15.7 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EIW70063.1 - 0.0051 16.8 0.1 0.035 14.0 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 EIW70063.1 - 0.032 13.8 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW70063.1 - 0.046 13.8 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIW70063.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 NTPase ArsA_ATPase PF02374.10 EIW70063.1 - 0.16 10.9 0.5 3.7 6.5 0.0 2.6 3 0 0 3 3 3 0 Anion-transporting ATPase CM_2 PF01817.16 EIW70066.1 - 9.1e-10 38.5 0.0 2.2e-08 34.0 0.0 2.7 3 0 0 3 3 3 1 Chorismate mutase type II Cupin_5 PF06172.6 EIW70067.1 - 4.1e-14 52.6 0.0 7.6e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Formyl_trans_N PF00551.14 EIW70068.1 - 7.5e-39 133.1 0.0 1.3e-20 73.6 0.0 2.2 2 0 0 2 2 2 2 Formyl transferase eIF3_N PF09440.5 EIW70070.1 - 1.2e-41 141.9 1.1 2e-41 141.3 0.8 1.3 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EIW70070.1 - 5.1e-09 36.3 0.3 2.4e-08 34.2 0.0 2.3 3 0 0 3 3 3 1 PCI domain Vinculin PF01044.14 EIW70070.1 - 0.037 12.0 0.2 0.052 11.5 0.1 1.1 1 0 0 1 1 1 0 Vinculin family DUF4158 PF13700.1 EIW70071.1 - 0.0024 17.3 0.0 0.0085 15.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4158) COX15-CtaA PF02628.10 EIW70072.1 - 7.3e-94 314.0 2.9 9.2e-94 313.6 2.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Y_phosphatase PF00102.22 EIW70073.1 - 4.8e-32 111.1 0.0 3.9e-17 62.3 0.0 3.1 3 0 0 3 3 3 3 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIW70073.1 - 1.6e-05 25.0 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EIW70073.1 - 0.00053 19.5 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EIW70073.1 - 0.18 12.0 0.3 0.64 10.2 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family IDO PF01231.13 EIW70074.1 - 1.8e-127 425.2 0.0 2.2e-127 425.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase THF_DHG_CYH_C PF02882.14 EIW70075.1 - 1.4e-12 47.0 2.4 6.5e-10 38.3 1.6 3.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EIW70075.1 - 2.8e-11 43.4 0.0 5.9e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Fungal_trans PF04082.13 EIW70076.1 - 2.7e-09 36.2 0.1 2.7e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW70076.1 - 3.5e-07 30.0 9.4 6.5e-07 29.1 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 EIW70076.1 - 0.016 14.9 3.8 0.96 9.1 0.0 2.7 1 1 1 2 2 2 0 Serglycin DUF1706 PF08020.6 EIW70076.1 - 0.038 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) Hid1 PF12722.2 EIW70076.1 - 0.45 8.1 6.7 0.67 7.5 4.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DNA_gyraseA_C PF03989.8 EIW70077.1 - 0.14 11.5 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller CIAPIN1 PF05093.8 EIW70079.1 - 8.4e-36 122.0 3.3 1.2e-35 121.5 2.3 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Ribosomal_L1 PF00687.16 EIW70080.1 - 4.3e-16 58.9 0.0 5.1e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PK PF00224.16 EIW70081.1 - 1.7e-162 539.9 0.7 2.2e-162 539.5 0.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EIW70081.1 - 9.2e-32 109.0 0.0 2.1e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EIW70081.1 - 1.8e-05 23.7 1.0 6.3e-05 21.9 0.7 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EIW70081.1 - 0.048 12.5 0.3 2.3 7.0 0.0 2.3 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Dabb PF07876.7 EIW70082.1 - 6.9e-14 52.0 0.1 7.9e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1330 PF07045.6 EIW70082.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) DAHP_synth_2 PF01474.11 EIW70083.1 - 2.3e-195 649.1 0.0 2.6e-195 648.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family MRP-S28 PF10213.4 EIW70084.1 - 1.6e-22 79.9 0.0 2.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein AA_permease PF00324.16 EIW70085.1 - 5e-116 387.8 47.0 6.1e-116 387.5 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW70085.1 - 7.5e-42 143.3 50.9 9.2e-42 143.0 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.2 EIW70086.1 - 4.3e-07 30.0 0.1 1.7e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW70086.1 - 6.9e-07 29.1 0.1 1.7e-06 27.8 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW70086.1 - 0.044 13.6 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase ATP12 PF07542.6 EIW70087.1 - 1.4e-39 134.7 0.1 2.1e-39 134.2 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Mito_carr PF00153.22 EIW70088.1 - 3.6e-54 180.4 1.2 1e-18 66.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein C2 PF00168.25 EIW70089.1 - 1.8e-81 268.0 0.4 5.8e-19 67.7 0.0 7.0 7 0 0 7 7 7 5 C2 domain DUF2404 PF10296.4 EIW70089.1 - 0.021 14.9 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) DUF4131 PF13567.1 EIW70089.1 - 0.064 12.6 1.1 0.13 11.6 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ELO PF01151.13 EIW70089.1 - 0.22 10.7 0.6 0.35 10.1 0.4 1.2 1 0 0 1 1 1 0 GNS1/SUR4 family SWIB PF02201.13 EIW70091.1 - 4.1e-26 90.4 0.0 6.6e-26 89.7 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EIW70091.1 - 8.8e-05 22.1 0.1 0.00034 20.3 0.0 2.0 2 0 0 2 2 2 1 DEK C terminal domain Pkinase_Tyr PF07714.12 EIW70092.1 - 1e-42 146.0 0.0 1.2e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIW70092.1 - 2.3e-36 125.2 0.0 2.7e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EIW70092.1 - 0.00034 19.6 0.0 0.00045 19.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW70092.1 - 0.005 15.9 0.0 0.0087 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW70092.1 - 0.022 14.4 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EIW70092.1 - 0.023 14.0 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Brix PF04427.13 EIW70093.1 - 1e-38 132.9 0.0 1.6e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Brix domain NTP_transferase PF00483.18 EIW70094.1 - 9.2e-46 156.1 0.0 8.6e-45 152.9 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EIW70094.1 - 9.6e-10 37.5 6.9 6.4e-06 25.4 0.6 4.2 1 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EIW70094.1 - 9.4e-09 35.5 0.0 2.3e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EIW70094.1 - 0.04 13.4 4.7 0.14 11.7 0.9 3.2 2 2 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF2080 PF09853.4 EIW70094.1 - 0.11 12.2 0.1 6.3 6.6 0.0 3.1 3 0 0 3 3 3 0 Putative transposon-encoded protein (DUF2080) Ribosomal_L24e PF01246.15 EIW70095.1 - 7.9e-32 108.9 3.5 2.2e-31 107.5 2.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e DUF3847 PF12958.2 EIW70095.1 - 0.017 14.8 1.4 0.028 14.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Flu_M1 PF00598.14 EIW70095.1 - 0.084 12.2 0.3 0.15 11.4 0.1 1.4 1 1 0 1 1 1 0 Influenza Matrix protein (M1) zf-FCS PF06467.9 EIW70095.1 - 0.1 12.2 4.8 0.19 11.3 3.4 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF2116 PF09889.4 EIW70095.1 - 5.2 6.9 7.5 0.27 11.0 0.5 2.4 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF1014 PF06244.7 EIW70097.1 - 9.4e-22 77.5 15.6 5.1e-21 75.1 10.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Peptidase_S64 PF08192.6 EIW70097.1 - 7.9 4.6 8.2 9.4 4.4 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ribosomal_S4e PF00900.15 EIW70098.1 - 1.8e-31 107.6 0.2 5.2e-31 106.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EIW70098.1 - 4.2e-21 74.5 4.1 1e-20 73.2 2.9 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 EIW70098.1 - 1.7e-06 27.5 4.5 5.8e-06 25.8 3.1 2.0 1 0 0 1 1 1 1 KOW motif S4 PF01479.20 EIW70098.1 - 3.4e-05 23.1 0.3 8e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 S4 domain Inositol_P PF00459.20 EIW70099.1 - 1e-71 241.4 0.0 1.2e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family WD40 PF00400.27 EIW70100.1 - 2.4e-22 77.9 2.7 1.7e-07 30.8 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EIW70100.1 - 0.00084 19.0 0.0 0.2 11.3 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Herpes_ORF11 PF04797.8 EIW70100.1 - 0.02 13.3 0.0 0.029 12.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein DnaJ-X PF14308.1 EIW70101.1 - 5.5e-46 156.4 3.6 1e-45 155.5 2.5 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 EIW70101.1 - 1.4e-25 88.7 1.8 1.4e-25 88.7 1.2 2.7 3 0 0 3 3 3 1 DnaJ domain zinc_ribbon_5 PF13719.1 EIW70101.1 - 0.0091 15.5 1.7 0.037 13.6 1.2 2.1 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIW70101.1 - 0.013 15.1 1.8 0.054 13.1 1.3 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-LSD1 PF06943.7 EIW70101.1 - 0.055 13.0 0.7 0.13 11.9 0.5 1.6 1 1 0 1 1 1 0 LSD1 zinc finger PYC_OADA PF02436.13 EIW70101.1 - 0.058 12.8 0.6 0.87 8.9 0.0 2.4 2 0 0 2 2 2 0 Conserved carboxylase domain p47_phox_C PF08944.6 EIW70101.1 - 3.4 7.9 22.0 6.8 6.9 5.2 3.1 1 1 1 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain PepSY_TM_2 PF13703.1 EIW70102.1 - 0.023 14.8 0.3 0.04 14.0 0.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix DUF1049 PF06305.6 EIW70102.1 - 0.024 14.0 0.2 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4381 PF14316.1 EIW70102.1 - 0.073 13.1 2.0 0.085 12.9 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4098 PF13345.1 EIW70103.1 - 0.03 14.2 0.1 0.21 11.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4098) DUF1499 PF07386.6 EIW70104.1 - 0.029 14.5 1.3 0.029 14.5 0.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1499) DUF2361 PF10153.4 EIW70104.1 - 0.75 9.9 5.7 0.14 12.3 0.5 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) TFIIS_C PF01096.13 EIW70105.1 - 4.5e-15 55.0 6.5 4.9e-15 54.8 0.3 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EIW70105.1 - 2.6e-06 27.0 1.4 2.6e-06 27.0 1.0 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.1 EIW70105.1 - 0.00022 20.2 11.0 0.0052 15.9 1.5 3.8 3 1 1 4 4 4 1 zinc-ribbon domain DZR PF12773.2 EIW70105.1 - 0.00027 20.6 10.6 0.00031 20.5 0.6 3.1 2 1 1 3 3 3 1 Double zinc ribbon Zn-ribbon_8 PF09723.5 EIW70105.1 - 0.0031 17.4 11.3 2.9 7.9 0.2 4.1 3 1 1 4 4 4 1 Zinc ribbon domain Baculo_LEF5_C PF11792.3 EIW70105.1 - 0.0089 15.3 1.7 0.0089 15.3 1.2 2.6 2 1 1 3 3 3 1 Baculoviridae late expression factor 5 C-terminal domain DUF2387 PF09526.5 EIW70105.1 - 0.03 14.2 8.2 1.7 8.6 0.3 3.2 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) Rpr2 PF04032.11 EIW70105.1 - 0.093 12.6 4.5 0.13 12.1 0.1 2.6 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_2 PF13240.1 EIW70105.1 - 0.1 12.1 15.6 1.2 8.7 2.5 4.0 3 1 0 3 3 3 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EIW70105.1 - 0.1 12.0 10.0 1.6 8.2 0.5 3.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit OrfB_Zn_ribbon PF07282.6 EIW70105.1 - 0.15 11.7 6.1 1.1 8.9 0.1 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF2082 PF09855.4 EIW70105.1 - 0.18 11.7 8.3 7.7 6.4 0.0 3.4 3 1 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF2296 PF10058.4 EIW70105.1 - 0.18 11.5 3.8 2.4 7.9 0.0 3.5 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_Tnp_IS1595 PF12760.2 EIW70105.1 - 0.26 11.1 10.8 0.65 9.8 1.1 3.1 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zf-FPG_IleRS PF06827.9 EIW70105.1 - 0.29 10.8 5.3 14 5.4 0.0 4.0 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS A2L_zn_ribbon PF08792.5 EIW70105.1 - 0.3 10.6 9.8 22 4.6 0.1 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain IBR PF01485.16 EIW70105.1 - 0.41 10.5 7.9 0.51 10.2 0.4 2.6 2 1 0 2 2 2 0 IBR domain PHD PF00628.24 EIW70105.1 - 2.3 7.9 7.4 0.31 10.7 0.3 2.5 2 1 0 2 2 2 0 PHD-finger RRN7 PF11781.3 EIW70105.1 - 2.4 7.7 12.7 6.6 6.3 0.9 4.1 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_5 PF13719.1 EIW70105.1 - 2.6 7.7 10.4 14 5.3 0.6 3.8 3 1 0 3 3 3 0 zinc-ribbon domain Ribosomal_S27e PF01667.12 EIW70105.1 - 2.6 7.6 9.3 30 4.2 0.1 3.8 3 1 1 4 4 4 0 Ribosomal protein S27 zf-RING_3 PF14369.1 EIW70105.1 - 4.4 7.3 7.4 2.4 8.2 1.4 3.0 3 1 1 4 4 4 0 zinc-finger Fer4_9 PF13187.1 EIW70105.1 - 4.7 7.5 7.0 52 4.2 4.9 2.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Auto_anti-p27 PF06677.7 EIW70105.1 - 5.3 6.8 8.5 1.1 9.0 0.7 3.1 4 0 0 4 4 4 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF951 PF06107.6 EIW70105.1 - 5.4 6.6 5.8 25 4.4 0.1 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF951) Stc1 PF12898.2 EIW70105.1 - 5.8 7.0 7.4 5.5 7.1 0.4 2.6 2 1 0 2 2 2 0 Stc1 domain zinc_ribbon_4 PF13717.1 EIW70105.1 - 6.7 6.5 11.2 41 3.9 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain G-patch_2 PF12656.2 EIW70106.1 - 7.2e-20 70.6 0.0 2.1e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site V-ATPase_H_N PF03224.9 EIW70107.1 - 1.9e-75 253.8 0.0 1.2e-74 251.2 0.0 1.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EIW70107.1 - 1.8e-36 124.6 0.1 8.2e-36 122.5 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.1 EIW70107.1 - 5.6e-06 26.5 0.3 0.0089 16.2 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 EIW70107.1 - 0.003 17.5 0.4 0.08 13.0 0.0 3.4 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 EIW70107.1 - 0.0093 15.7 2.3 11 5.9 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF2019 PF09450.5 EIW70107.1 - 0.07 12.9 0.3 0.58 10.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2019) CTNNBL PF08216.6 EIW70107.1 - 0.081 12.5 0.0 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear BTB PF00651.26 EIW70108.1 - 1.5e-12 47.4 1.0 9.3e-06 25.6 0.1 2.3 2 0 0 2 2 2 2 BTB/POZ domain Skp1_POZ PF03931.10 EIW70108.1 - 5.2e-05 23.2 0.1 0.031 14.3 0.0 2.5 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain DUF1366 PF07104.6 EIW70108.1 - 0.0094 15.5 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1366) BTB PF00651.26 EIW70109.1 - 4.3e-07 29.8 0.0 6.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 EIW70109.1 - 0.0079 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Sec7 PF01369.15 EIW70110.1 - 6.6e-37 127.0 0.0 1.3e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain ABM PF03992.11 EIW70110.1 - 4.6e-08 32.9 0.1 1.4e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase BTB PF00651.26 EIW70110.1 - 5.9e-08 32.6 0.1 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PH_9 PF15410.1 EIW70110.1 - 2.3e-06 27.7 0.0 5.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIW70110.1 - 8.3e-06 25.9 0.0 2.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 PH domain Tmemb_cc2 PF10267.4 EIW70110.1 - 0.01 14.4 0.4 0.028 13.0 0.3 1.7 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1445 PF07286.7 EIW70111.1 - 1.4e-52 177.1 0.0 1.8e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Ribonuc_L-PSP PF01042.16 EIW70112.1 - 3.8e-16 58.9 0.0 4.8e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP 2OG-FeII_Oxy PF03171.15 EIW70113.1 - 5.4e-11 42.6 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIW70113.1 - 9.1e-09 35.8 0.0 1.8e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Fungal_trans PF04082.13 EIW70114.1 - 6.6e-12 44.8 0.1 9.5e-12 44.3 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EIW70115.1 - 6.6e-30 104.0 26.6 8.3e-30 103.6 17.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily 4HBT PF03061.17 EIW70116.1 - 1.4e-15 57.1 0.1 1.9e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EIW70116.1 - 0.026 14.2 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.1 EIW70116.1 - 0.039 13.9 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) YIF1 PF03878.10 EIW70117.1 - 3e-75 252.4 0.2 3.7e-75 252.1 0.1 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EIW70117.1 - 0.0022 17.5 7.0 0.0044 16.5 4.8 1.6 1 0 0 1 1 1 1 Yip1 domain RRM_6 PF14259.1 EIW70118.1 - 3.5e-19 68.5 0.3 6.3e-08 32.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW70118.1 - 5.8e-19 67.5 2.4 2.6e-06 26.9 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW70118.1 - 0.00013 21.7 0.1 0.35 10.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1676 PF07898.8 EIW70118.1 - 0.35 11.1 5.9 0.14 12.4 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1676) Fungal_trans PF04082.13 EIW70119.1 - 1.3e-25 89.7 0.0 2.2e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dak1 PF02733.12 EIW70120.1 - 2.5e-104 348.3 0.2 3.4e-104 347.9 0.1 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EIW70120.1 - 4.3e-43 146.9 1.4 6.6e-43 146.3 0.9 1.3 1 0 0 1 1 1 1 DAK2 domain DUF349 PF03993.7 EIW70120.1 - 0.26 11.4 0.4 10 6.3 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Mito_carr PF00153.22 EIW70121.1 - 2.5e-71 235.4 0.0 1.7e-26 91.7 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Skp1 PF01466.14 EIW70122.1 - 3.7e-40 135.8 0.8 5.8e-40 135.1 0.5 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EIW70122.1 - 1.1e-22 79.9 0.7 2.2e-22 78.9 0.2 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EIW70122.1 - 7.5e-05 22.6 0.1 0.0022 17.9 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain AAA PF00004.24 EIW70123.1 - 1.1e-91 303.9 0.0 4.7e-48 162.7 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIW70123.1 - 1.2e-11 44.1 0.0 8.7e-05 21.6 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIW70123.1 - 1.9e-11 44.2 2.6 0.0011 19.0 0.0 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 EIW70123.1 - 1.6e-10 41.0 0.0 7.9e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW70123.1 - 9.2e-10 38.7 0.4 0.0026 17.8 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EIW70123.1 - 9.5e-09 36.1 0.0 0.001 19.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIW70123.1 - 5.6e-08 32.6 1.8 0.0011 18.6 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EIW70123.1 - 1.9e-07 30.3 0.0 0.0014 17.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_2 PF07724.9 EIW70123.1 - 2.2e-07 30.9 0.0 0.00032 20.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EIW70123.1 - 2.8e-07 30.5 0.0 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIW70123.1 - 1e-06 28.3 3.0 0.018 14.7 0.1 3.2 2 2 0 2 2 2 2 Part of AAA domain AAA_3 PF07726.6 EIW70123.1 - 3.8e-06 26.5 0.0 0.0078 15.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EIW70123.1 - 8.3e-06 25.4 0.0 0.021 14.3 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 EIW70123.1 - 1.6e-05 23.8 0.0 0.14 10.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_28 PF13521.1 EIW70123.1 - 4.7e-05 23.4 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EIW70123.1 - 4.8e-05 23.0 3.0 0.52 9.9 0.0 3.8 3 1 1 4 4 4 2 NACHT domain AAA_25 PF13481.1 EIW70123.1 - 5.7e-05 22.5 5.0 2.5 7.4 0.0 4.2 2 2 2 4 4 4 2 AAA domain RNA_helicase PF00910.17 EIW70123.1 - 8.9e-05 22.6 0.0 0.033 14.3 0.0 2.8 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.12 EIW70123.1 - 0.0001 21.7 0.5 0.011 15.1 0.0 2.7 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.1 EIW70123.1 - 0.00011 22.5 0.0 0.6 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EIW70123.1 - 0.00021 20.5 0.9 0.045 12.8 0.0 2.6 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EIW70123.1 - 0.00028 20.0 0.1 0.97 8.5 0.0 3.3 3 0 0 3 3 3 1 KaiC DUF815 PF05673.8 EIW70123.1 - 0.00045 19.2 0.0 0.052 12.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EIW70123.1 - 0.00051 20.3 0.1 0.31 11.3 0.0 2.6 2 1 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 EIW70123.1 - 0.00061 19.3 0.0 0.3 10.5 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EIW70123.1 - 0.00069 19.5 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family UPF0079 PF02367.12 EIW70123.1 - 0.0033 17.0 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EIW70123.1 - 0.0038 16.9 0.0 1.7 8.2 0.0 3.1 2 2 1 3 3 3 1 Archaeal ATPase SKI PF01202.17 EIW70123.1 - 0.007 16.2 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Sigma54_activ_2 PF14532.1 EIW70123.1 - 0.0078 16.2 0.0 0.26 11.3 0.0 2.7 2 1 1 3 3 2 1 Sigma-54 interaction domain CPT PF07931.7 EIW70123.1 - 0.02 14.5 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.17 EIW70123.1 - 0.039 12.8 0.0 0.32 9.8 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 EIW70123.1 - 0.051 12.2 0.0 4.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 EIW70123.1 - 0.12 12.1 0.1 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.1 EIW70123.1 - 0.16 11.5 0.0 6.6 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 EIW70125.1 - 8.6e-34 114.2 1.0 1.7e-09 37.1 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EIW70125.1 - 4.2e-05 23.3 0.0 0.037 13.7 0.0 3.3 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW70125.1 - 0.016 14.8 1.9 17 5.2 0.1 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Spt5-NGN PF03439.8 EIW70126.1 - 3.8e-16 58.6 0.0 2.1e-15 56.2 0.0 2.2 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EIW70126.1 - 1e-13 51.6 12.0 1e-13 51.6 8.3 2.9 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 EIW70126.1 - 3.8e-12 46.7 18.6 2.7e-10 40.7 9.3 3.0 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 EIW70126.1 - 2.6e-11 42.7 29.8 0.00011 21.7 1.6 6.4 7 0 0 7 7 7 4 KOW motif LysM PF01476.15 EIW70126.1 - 0.13 12.2 0.0 0.71 9.8 0.0 2.1 2 0 0 2 2 2 0 LysM domain Drc1-Sld2 PF11719.3 EIW70126.1 - 5.2 6.0 19.5 8.7 5.3 13.5 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Ribosomal_L27 PF01016.14 EIW70128.1 - 6e-34 115.6 0.7 6.6e-34 115.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein CAP59_mtransfer PF11735.3 EIW70129.1 - 5.4e-72 241.9 0.1 7.5e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ion_trans PF00520.26 EIW70129.1 - 0.015 14.5 0.3 0.043 13.0 0.1 1.6 1 1 1 2 2 2 0 Ion transport protein DUF3999 PF13163.1 EIW70129.1 - 0.045 12.6 0.1 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) Phosducin PF02114.11 EIW70130.1 - 5.6e-11 41.6 0.0 0.0021 16.8 0.0 3.1 2 1 1 3 3 3 3 Phosducin Cytochrom_C PF00034.16 EIW70132.1 - 1.1e-08 35.7 0.5 2.3e-08 34.7 0.3 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EIW70132.1 - 3e-07 30.4 4.0 2.8e-06 27.3 2.8 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EIW70132.1 - 0.00041 19.8 0.3 0.0055 16.1 0.1 2.2 2 0 0 2 2 2 1 Cytochrome c-550 domain Pkinase PF00069.20 EIW70133.1 - 5.7e-57 192.8 0.0 9e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW70133.1 - 3.5e-18 65.6 0.0 6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinesin PF00225.18 EIW70134.1 - 2.3e-111 371.7 0.3 3.5e-111 371.1 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EIW70134.1 - 3.9e-28 97.8 1.6 4.6e-28 97.6 0.1 2.0 2 0 0 2 2 2 1 Kinesin protein PH PF00169.24 EIW70134.1 - 2.4e-07 30.9 0.0 8.1e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 PH domain FHA PF00498.21 EIW70134.1 - 1.1e-06 28.6 0.0 1.2e-05 25.3 0.0 2.9 2 0 0 2 2 2 1 FHA domain Defensin_beta PF00711.14 EIW70134.1 - 0.56 10.1 0.1 0.97 9.4 0.1 1.4 1 0 0 1 1 1 0 Beta defensin TIP49 PF06068.8 EIW70135.1 - 9.4e-179 594.2 1.0 1.1e-178 594.0 0.7 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EIW70135.1 - 5.3e-07 29.8 0.1 0.0004 20.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIW70135.1 - 5.6e-07 28.8 2.1 0.00065 18.8 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EIW70135.1 - 3.3e-05 22.8 0.1 5.7e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 EIW70135.1 - 0.00019 20.6 1.3 0.0063 15.6 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EIW70135.1 - 0.00057 20.0 0.2 0.76 9.9 0.0 2.7 1 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIW70135.1 - 0.00057 19.6 0.3 0.52 10.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW70135.1 - 0.0018 18.2 0.1 0.011 15.7 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EIW70135.1 - 0.0044 16.9 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EIW70135.1 - 0.0047 16.0 0.1 0.012 14.7 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EIW70135.1 - 0.0057 16.0 0.1 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW70135.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIW70135.1 - 0.059 12.8 0.1 2.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain KTI12 PF08433.5 EIW70135.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Daxx PF03344.10 EIW70137.1 - 0.0007 18.2 4.4 0.0007 18.2 3.1 2.0 2 0 0 2 2 2 1 Daxx Family Nop14 PF04147.7 EIW70137.1 - 0.52 8.1 11.7 0.73 7.6 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EIW70137.1 - 3.4 6.8 14.0 6.3 5.9 9.7 1.3 1 0 0 1 1 1 0 SDA1 zf-CCHC PF00098.18 EIW70138.1 - 0.0002 21.1 2.0 0.00034 20.3 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIW70138.1 - 0.012 15.0 0.1 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW70138.1 - 0.019 15.1 5.9 0.035 14.3 4.1 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain rve PF00665.21 EIW70139.1 - 5.4e-21 74.9 0.0 1.1e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIW70139.1 - 8.2e-19 67.8 0.0 1.5e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIW70139.1 - 2.3e-07 31.2 0.0 6e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIW70139.1 - 7.4e-07 28.9 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 EIW70139.1 - 5.6e-06 26.3 0.0 1.5e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.6 EIW70139.1 - 0.00042 20.2 0.0 0.00076 19.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EIW70139.1 - 0.0015 18.3 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIW70139.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease PNK3P PF08645.6 EIW70140.1 - 2.8e-42 143.8 0.0 3.6e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase LNS2 PF08235.8 EIW70140.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Hydrolase_like PF13242.1 EIW70140.1 - 0.084 12.5 0.1 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 HAD-hyrolase-like Glycos_transf_3 PF00591.16 EIW70141.1 - 2.2e-79 266.4 0.0 2.9e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EIW70141.1 - 1e-10 41.0 0.0 1.7e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Acyl-CoA_dh_M PF02770.14 EIW70141.1 - 0.089 12.3 0.6 0.18 11.3 0.4 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Peptidase_M19 PF01244.16 EIW70142.1 - 2.1e-94 316.0 0.0 2.5e-94 315.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Aminotran_3 PF00202.16 EIW70143.1 - 3.5e-98 328.5 0.0 4.3e-98 328.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Glycolytic PF00274.14 EIW70143.1 - 0.16 10.3 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Fungal_trans PF04082.13 EIW70144.1 - 0.077 11.8 0.0 3.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain Peptidase_M19 PF01244.16 EIW70145.1 - 6e-90 301.4 0.0 7.5e-90 301.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MFS_1 PF07690.11 EIW70146.1 - 2e-31 109.0 34.6 2.6e-31 108.6 24.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fumarate_red_C PF02300.12 EIW70146.1 - 0.053 13.3 0.3 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Fumarate reductase subunit C DUF2243 PF10002.4 EIW70146.1 - 0.34 10.6 5.9 0.055 13.2 0.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) WSC PF01822.14 EIW70147.1 - 3e-16 59.1 7.1 3e-16 59.1 4.9 2.5 2 0 0 2 2 2 1 WSC domain Yeast_MT PF11403.3 EIW70147.1 - 0.02 15.0 4.2 0.038 14.1 2.9 1.4 1 0 0 1 1 1 0 Yeast metallothionein Drc1-Sld2 PF11719.3 EIW70147.1 - 6 5.8 9.8 7.2 5.5 6.8 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein NifU_N PF01592.11 EIW70148.1 - 2.1e-50 169.9 0.1 3e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain Pkinase PF00069.20 EIW70149.1 - 2.8e-65 220.0 0.0 4.2e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW70149.1 - 2e-28 99.1 0.0 3.1e-20 72.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW70149.1 - 1.3e-05 24.3 0.2 0.56 9.1 0.0 3.1 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 EIW70149.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family X PF00739.14 EIW70149.1 - 2.7 7.8 4.1 5.5 6.8 2.8 1.4 1 0 0 1 1 1 0 Trans-activation protein X TPR_11 PF13414.1 EIW70151.1 - 3.2e-18 65.1 0.3 5e-09 35.6 0.0 5.0 4 1 2 6 6 6 3 TPR repeat TPR_1 PF00515.23 EIW70151.1 - 3.4e-13 48.5 1.2 6.9e-05 22.2 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW70151.1 - 7.1e-09 35.1 0.0 0.0033 17.4 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW70151.1 - 3.3e-08 33.4 0.5 0.0051 17.3 0.0 5.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIW70151.1 - 4.4e-08 33.5 0.1 3.4e-05 24.3 0.0 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW70151.1 - 6.1e-08 32.4 0.0 8.5e-05 22.4 0.0 4.3 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW70151.1 - 6.5e-08 31.9 10.5 2.2e-05 23.9 0.0 5.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW70151.1 - 3.5e-06 26.3 0.6 0.082 12.7 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIW70151.1 - 1.7e-05 24.2 3.2 0.47 10.3 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIW70151.1 - 2.4e-05 24.0 0.1 0.0016 18.2 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIW70151.1 - 6.2e-05 23.2 0.0 0.0017 18.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EIW70151.1 - 0.0038 17.3 0.1 0.065 13.3 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIW70151.1 - 0.01 16.2 0.3 1.3 9.6 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat FlaC_arch PF05377.6 EIW70151.1 - 0.039 13.8 2.8 0.32 10.9 0.4 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Helicase_C_2 PF13307.1 EIW70152.1 - 2.5e-53 180.4 0.0 1.7e-52 177.7 0.0 2.4 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EIW70152.1 - 1.6e-46 157.9 0.0 3.1e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 EIW70152.1 - 7.3e-05 22.6 2.3 0.035 13.9 0.6 3.4 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 EIW70152.1 - 0.00069 19.1 0.0 0.62 9.5 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.1 EIW70152.1 - 0.0021 18.1 0.2 2.1 8.4 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIW70152.1 - 0.022 14.5 0.1 0.45 10.3 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain SelR PF01641.13 EIW70153.1 - 3.2e-51 172.1 0.1 3.7e-51 171.9 0.0 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 EIW70153.1 - 0.00074 19.2 1.3 0.026 14.2 0.0 2.3 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) Yippee-Mis18 PF03226.9 EIW70153.1 - 0.048 13.7 2.5 0.23 11.5 1.7 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EIW70153.1 - 0.076 12.8 0.5 0.98 9.2 0.0 2.2 2 1 0 2 2 2 0 C-terminal domain of RIG-I Zn_Tnp_IS1595 PF12760.2 EIW70153.1 - 0.11 12.2 1.5 4.8 7.0 0.1 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 EIW70153.1 - 0.12 12.1 4.6 0.91 9.3 3.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon NOB1_Zn_bind PF08772.6 EIW70153.1 - 1.5 8.6 5.1 2.3 8.1 1.0 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DEAD PF00270.24 EIW70155.1 - 2.7e-11 43.2 0.0 6.8e-11 41.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW70155.1 - 1.8e-08 34.1 0.0 3.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MbeD_MobD PF04899.7 EIW70155.1 - 0.066 13.1 3.5 0.2 11.5 0.2 2.4 2 0 0 2 2 2 0 MbeD/MobD like Reo_sigmaC PF04582.7 EIW70155.1 - 0.13 11.3 0.6 3.2 6.8 0.2 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein FlxA PF14282.1 EIW70155.1 - 0.39 10.6 9.8 4 7.4 1.5 2.4 2 0 0 2 2 2 0 FlxA-like protein SlyX PF04102.7 EIW70155.1 - 3.7 7.9 6.3 2.3 8.6 0.7 2.4 2 0 0 2 2 2 0 SlyX KOW PF00467.24 EIW70156.1 - 4.3e-10 38.9 4.4 8.4e-10 37.9 2.6 1.9 1 1 1 2 2 2 1 KOW motif Methyltrans_RNA PF04452.9 EIW70156.1 - 0.02 14.0 0.3 0.024 13.7 0.2 1.2 1 0 0 1 1 1 0 RNA methyltransferase Cut12 PF11500.3 EIW70156.1 - 0.041 13.5 0.2 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Spindle pole body formation-associated protein DUF1021 PF06257.6 EIW70156.1 - 0.24 11.1 1.4 0.87 9.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1021) EB1 PF03271.12 EIW70157.1 - 1.2e-11 44.4 0.1 2.7e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EIW70157.1 - 3.1e-08 33.5 0.3 6.4e-08 32.5 0.1 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF812 PF05667.6 EIW70157.1 - 0.026 13.0 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Herpes_UL6 PF01763.11 EIW70157.1 - 0.11 10.6 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like LSM PF01423.17 EIW70160.1 - 1.1e-13 50.4 0.4 1.5e-13 50.0 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIW70160.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.4 1 1 0 1 1 1 1 Ataxin 2 SM domain TPR_11 PF13414.1 EIW70161.1 - 8.7e-12 44.5 5.2 1.6e-06 27.6 0.2 3.0 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EIW70161.1 - 5.8e-07 28.8 5.2 0.01 15.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW70161.1 - 3.4e-05 23.6 2.4 0.27 11.5 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW70161.1 - 0.0002 21.0 5.5 0.0065 16.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIW70161.1 - 0.01 15.7 0.5 0.029 14.2 0.0 1.9 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EIW70161.1 - 0.06 13.1 2.1 0.097 12.5 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIW70161.1 - 0.08 13.6 1.8 0.2 12.3 1.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW70161.1 - 0.089 12.6 2.0 5.1 7.1 0.6 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Actin PF00022.14 EIW70162.1 - 2.4e-126 421.3 0.0 2.7e-126 421.1 0.0 1.0 1 0 0 1 1 1 1 Actin U3_assoc_6 PF08640.6 EIW70164.1 - 3.8e-27 93.8 1.6 2.6e-26 91.1 1.1 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EIW70164.1 - 0.11 13.2 1.0 11 6.9 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat FUN14 PF04930.10 EIW70165.1 - 4.6e-22 78.1 0.7 5.2e-22 78.0 0.5 1.0 1 0 0 1 1 1 1 FUN14 family Glyco_hydro_31 PF01055.21 EIW70166.1 - 3.5e-144 480.8 0.8 5.9e-144 480.1 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW70166.1 - 1.3e-17 63.3 0.0 3.8e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Peptidase_M41 PF01434.13 EIW70170.1 - 2.6e-70 236.1 0.0 3.7e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EIW70170.1 - 8.4e-43 145.7 0.0 2e-42 144.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EIW70170.1 - 2.7e-08 33.9 0.1 6.2e-08 32.7 0.0 1.7 2 0 0 2 2 1 1 FtsH Extracellular AAA_17 PF13207.1 EIW70170.1 - 0.00093 20.0 0.0 0.0036 18.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EIW70170.1 - 0.0018 18.3 0.0 0.18 11.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EIW70170.1 - 0.0031 16.2 0.0 0.0051 15.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EIW70170.1 - 0.0041 16.8 0.6 0.013 15.2 0.4 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIW70170.1 - 0.01 15.8 0.3 0.075 13.0 0.1 2.5 2 1 1 3 3 3 0 AAA ATPase domain RuvB_N PF05496.7 EIW70170.1 - 0.011 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EIW70170.1 - 0.021 14.7 0.3 0.36 10.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIW70170.1 - 0.025 14.3 0.2 0.09 12.4 0.0 2.0 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EIW70170.1 - 0.035 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIW70170.1 - 0.035 13.1 0.0 0.072 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EIW70170.1 - 0.039 13.3 0.0 0.086 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW70170.1 - 0.082 13.2 0.1 0.51 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIW70170.1 - 0.11 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EIW70170.1 - 1.4 8.0 2.9 1.3 8.2 0.4 1.9 2 0 0 2 2 2 0 PhoH-like protein Oxidored_q2 PF00420.19 EIW70171.1 - 0.12 11.9 1.3 0.64 9.6 0.0 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L gag-asp_proteas PF13975.1 EIW70172.1 - 2.1e-07 30.6 0.0 4.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIW70172.1 - 2.6e-05 24.6 0.0 4.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIW70172.1 - 5.6e-05 23.1 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 EIW70172.1 - 0.0001 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A2B PF12384.3 EIW70172.1 - 0.00048 19.5 0.0 0.00072 18.9 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP PF00077.15 EIW70172.1 - 0.00079 19.3 0.0 0.003 17.4 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIW70172.1 - 0.0045 16.5 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 EIW70175.1 - 0.00061 19.5 1.5 0.0012 18.6 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle B56 PF01603.15 EIW70175.1 - 0.061 11.9 2.0 0.081 11.5 1.4 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) BRF1 PF07741.8 EIW70175.1 - 0.83 9.9 6.3 0.24 11.6 2.3 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain GTP_EFTU PF00009.22 EIW70178.1 - 1.7e-20 73.2 0.0 3.6e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIW70178.1 - 5.1e-13 49.0 0.1 1.5e-12 47.5 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIW70178.1 - 2e-07 31.0 1.7 7.3e-07 29.2 1.2 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIW70178.1 - 0.016 14.8 0.6 0.076 12.6 0.4 2.2 1 1 0 1 1 1 0 Elongation factor Tu domain 4 DUF2838 PF10998.3 EIW70179.1 - 7.7e-20 70.8 8.0 1.1e-17 63.9 5.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) DGF-1_C PF11040.3 EIW70179.1 - 0.24 11.2 3.9 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus RRM_6 PF14259.1 EIW70180.1 - 4.7e-31 106.5 0.2 1.5e-07 31.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW70180.1 - 4.7e-26 90.2 2.3 1.2e-09 37.6 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW70180.1 - 3.4e-21 74.8 0.4 5.6e-05 22.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW70180.1 - 1.1e-06 28.3 0.2 0.08 12.7 0.0 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Nab6_mRNP_bdg PF10567.4 EIW70180.1 - 0.0012 17.9 0.0 0.29 10.0 0.0 3.4 2 1 0 2 2 2 1 RNA-recognition motif RNA_bind PF08675.6 EIW70180.1 - 0.14 12.1 0.0 1.5 8.8 0.0 2.6 4 0 0 4 4 4 0 RNA binding domain Ribosomal_S3Ae PF01015.13 EIW70181.1 - 8.9e-81 269.8 4.1 1.1e-80 269.6 2.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EIW70181.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF3888 PF13027.1 EIW70181.1 - 0.17 11.7 0.8 5.5 6.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3888) PUF PF00806.14 EIW70182.1 - 5.1e-53 173.6 4.1 3.4e-09 35.6 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat BAR PF03114.13 EIW70183.1 - 1.1e-40 139.5 1.3 1.4e-40 139.2 0.9 1.1 1 0 0 1 1 1 1 BAR domain AAA_13 PF13166.1 EIW70183.1 - 7.8e-05 21.3 0.3 9.8e-05 21.0 0.2 1.1 1 0 0 1 1 1 1 AAA domain Arfaptin PF06456.8 EIW70183.1 - 0.00017 21.0 3.9 0.0023 17.3 2.7 2.1 1 1 0 1 1 1 1 Arfaptin-like domain Vps5 PF09325.5 EIW70183.1 - 0.059 12.6 1.3 0.58 9.3 0.1 2.1 2 0 0 2 2 2 0 Vps5 C terminal like AAA_27 PF13514.1 EIW70183.1 - 0.17 9.5 4.6 0.14 9.8 1.5 1.8 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EIW70184.1 - 3.9e-44 150.3 0.0 6.2e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EIW70184.1 - 3.6e-12 46.2 0.1 7.3e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 EIW70184.1 - 1.9e-10 40.7 0.0 5.3e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 EIW70184.1 - 6.2e-07 29.3 0.0 6e-06 26.1 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EIW70184.1 - 3.8e-06 26.9 0.2 1e-05 25.5 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIW70184.1 - 8.6e-05 22.1 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 G-alpha PF00503.15 EIW70184.1 - 0.0045 15.7 0.4 0.0097 14.6 0.3 1.5 1 0 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 EIW70184.1 - 0.04 14.3 0.2 2.6 8.5 0.0 3.2 2 1 0 2 2 2 0 Miro-like protein Ras PF00071.17 EIW70184.1 - 0.19 11.0 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Ras family S4 PF01479.20 EIW70185.1 - 4e-12 45.3 0.0 6.2e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EIW70185.1 - 0.023 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 S4 domain Glutaredoxin PF00462.19 EIW70186.1 - 2.6e-17 62.5 0.1 9e-17 60.8 0.1 1.8 2 0 0 2 2 2 1 Glutaredoxin Rhodanese PF00581.15 EIW70187.1 - 2.5e-05 24.5 0.0 3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain ATP_bind_1 PF03029.12 EIW70188.1 - 1.2e-77 260.6 0.0 1.4e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EIW70188.1 - 5.5e-07 30.4 0.0 1e-06 29.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EIW70188.1 - 5.2e-05 22.7 0.1 0.00023 20.6 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EIW70188.1 - 6e-05 21.9 0.0 0.0001 21.2 0.0 1.3 1 0 0 1 1 1 1 ArgK protein MobB PF03205.9 EIW70188.1 - 0.00023 20.8 0.0 0.0013 18.4 0.0 2.1 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EIW70188.1 - 0.00087 18.9 0.0 0.0028 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIW70188.1 - 0.0015 17.9 0.1 0.027 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW70188.1 - 0.0045 16.9 0.1 0.0098 15.8 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.1 EIW70188.1 - 0.0049 17.1 0.3 0.021 15.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW70188.1 - 0.0053 16.2 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EIW70188.1 - 0.0057 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EIW70188.1 - 0.0061 16.7 0.1 0.01 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW70188.1 - 0.0072 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain GTP_EFTU PF00009.22 EIW70188.1 - 0.0086 15.5 1.7 4.1 6.7 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.12 EIW70188.1 - 0.0089 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EIW70188.1 - 0.01 15.2 0.0 0.029 13.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 EIW70188.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 EIW70188.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EIW70188.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EIW70188.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.6 2 0 0 2 2 1 0 ABC transporter RNA_helicase PF00910.17 EIW70188.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EIW70188.1 - 0.021 14.7 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIW70188.1 - 0.026 14.2 0.8 0.057 13.1 0.1 1.8 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 EIW70188.1 - 0.028 14.0 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EIW70188.1 - 0.028 13.3 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 EIW70188.1 - 0.028 13.8 0.1 0.062 12.7 0.0 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain PPV_E1_C PF00519.12 EIW70188.1 - 0.029 13.0 0.0 0.045 12.3 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase Gtr1_RagA PF04670.7 EIW70188.1 - 0.044 12.9 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region cobW PF02492.14 EIW70188.1 - 0.05 13.0 0.1 0.72 9.2 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EIW70188.1 - 0.054 13.6 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.10 EIW70188.1 - 0.058 12.4 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Anion-transporting ATPase MipZ PF09140.6 EIW70188.1 - 0.059 12.4 0.0 6 5.8 0.0 2.4 2 0 0 2 2 2 0 ATPase MipZ NACHT PF05729.7 EIW70188.1 - 0.087 12.4 0.1 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 EIW70188.1 - 0.21 11.9 0.9 0.4 10.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EIW70189.1 - 7.9e-25 87.4 0.0 2.9e-08 33.0 0.0 3.2 3 1 0 3 3 3 3 Septin MMR_HSR1 PF01926.18 EIW70189.1 - 0.0011 18.8 0.0 0.0028 17.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EIW70189.1 - 0.0018 18.3 0.2 0.0037 17.2 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 EIW70189.1 - 0.0075 16.7 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EIW70189.1 - 0.017 14.3 0.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIW70189.1 - 0.054 12.9 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EIW70189.1 - 0.087 13.6 0.4 0.42 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EIW70189.1 - 0.088 11.7 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.1 EIW70189.1 - 0.14 12.3 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW70189.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase GDA1_CD39 PF01150.12 EIW70190.1 - 1.8e-80 270.6 0.0 6.1e-80 268.8 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Cellulase PF00150.13 EIW70191.1 - 5.6e-25 88.0 0.0 1.2e-24 87.0 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 EIW70191.1 - 0.0001 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_1 PF00232.13 EIW70191.1 - 0.00063 18.0 0.0 0.001 17.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 LRR_8 PF13855.1 EIW70192.1 - 3e-14 52.5 15.0 7.8e-10 38.3 1.8 3.8 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EIW70192.1 - 3.8e-14 51.9 19.6 4e-08 32.6 1.3 5.5 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIW70192.1 - 6.9e-10 37.5 22.2 0.062 13.3 0.0 7.4 6 1 0 6 6 6 3 Leucine Rich Repeat Abhydrolase_3 PF07859.8 EIW70192.1 - 3.5e-09 36.5 0.0 2.5e-08 33.7 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold LRR_7 PF13504.1 EIW70192.1 - 1e-07 30.9 11.7 0.11 12.7 0.0 7.0 7 0 0 7 7 6 2 Leucine rich repeat LRR_6 PF13516.1 EIW70192.1 - 9.2e-06 25.2 23.8 0.099 12.7 0.1 6.9 5 2 2 7 7 7 2 Leucine Rich repeat Peptidase_S9 PF00326.16 EIW70192.1 - 2e-05 23.9 0.0 0.0073 15.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW70192.1 - 0.00036 20.2 0.0 0.00076 19.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIW70192.1 - 0.019 14.3 0.3 0.5 9.7 0.1 2.6 2 1 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.11 EIW70192.1 - 0.02 14.3 0.2 0.43 9.9 0.1 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 EIW70192.1 - 0.02 13.3 0.0 0.33 9.3 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) COesterase PF00135.23 EIW70192.1 - 0.077 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family SRF-TF PF00319.13 EIW70194.1 - 1.3e-18 65.9 0.1 3.9e-18 64.4 0.0 1.8 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CtaG_Cox11 PF04442.9 EIW70195.1 - 8.7e-56 187.9 0.0 1.1e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Proteasome PF00227.21 EIW70196.1 - 7e-48 162.4 0.1 9.1e-48 162.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW70196.1 - 2.6e-15 55.4 1.3 6.1e-15 54.2 0.3 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2423 PF10338.4 EIW70197.1 - 3.9e-13 49.1 6.5 7.7e-13 48.1 4.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Radial_spoke PF04712.7 EIW70197.1 - 0.013 14.2 0.4 0.016 14.0 0.3 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein TMEM51 PF15345.1 EIW70197.1 - 0.96 9.0 4.1 1 8.9 2.8 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 MFS_1 PF07690.11 EIW70198.1 - 2.3e-33 115.4 29.8 3.6e-33 114.7 20.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW70198.1 - 0.0025 16.0 0.5 0.0037 15.5 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-DHHC PF01529.15 EIW70199.1 - 2e-30 105.4 4.1 3.7e-30 104.5 2.8 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Peptidase_M20 PF01546.23 EIW70200.1 - 1.1e-19 70.6 0.0 1.7e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIW70200.1 - 1.2e-13 50.7 0.0 2.1e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain COPI_assoc PF08507.5 EIW70201.1 - 3.5e-38 130.3 1.2 3.8e-38 130.2 0.9 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 EIW70201.1 - 2.1e-05 24.4 5.4 3e-05 23.9 3.7 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF308 PF03729.8 EIW70201.1 - 5.2 7.1 18.9 4 7.5 4.3 3.2 1 1 2 3 3 3 0 Short repeat of unknown function (DUF308) DUF4538 PF15061.1 EIW70201.1 - 6.1 6.2 7.3 0.34 10.2 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) BAH PF01426.13 EIW70202.1 - 1.5e-13 50.4 0.0 2.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 BAH domain Bromodomain PF00439.20 EIW70202.1 - 0.0011 18.8 0.0 0.0039 17.0 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Syja_N PF02383.13 EIW70203.1 - 1.9e-85 286.4 0.0 2.8e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EIW70203.1 - 8.7e-23 79.9 0.0 2.5e-22 78.4 0.0 1.8 2 0 0 2 2 2 1 Inositol phosphatase CN_hydrolase PF00795.17 EIW70204.1 - 2.3e-20 72.7 0.0 4.2e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase DUF402 PF04167.8 EIW70204.1 - 0.055 13.3 0.5 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF402) Myb_DNA-bind_4 PF13837.1 EIW70205.1 - 0.0014 18.7 0.2 0.0042 17.1 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Methyltransf_31 PF13847.1 EIW70206.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PIG-F PF06699.6 EIW70207.1 - 1.2e-31 110.0 2.5 2.3e-31 109.2 1.7 1.5 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF4310 PF14187.1 EIW70207.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) Sugar_tr PF00083.19 EIW70207.1 - 0.98 7.9 3.7 1.8 7.0 0.1 2.5 3 0 0 3 3 3 0 Sugar (and other) transporter DUF4131 PF13567.1 EIW70207.1 - 5.8 6.2 10.3 0.31 10.4 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) NST1 PF13945.1 EIW70218.1 - 0.0021 18.1 1.5 0.0021 18.1 1.0 1.9 2 0 0 2 2 2 1 Salt tolerance down-regulator RNA_pol_N PF01194.12 EIW70219.1 - 5.6e-29 99.9 0.2 6.5e-29 99.7 0.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Peptidase_C50 PF03568.12 EIW70220.1 - 6.4e-98 327.9 0.0 8e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 EIW70220.1 - 0.0037 16.4 0.0 0.047 12.8 0.0 2.4 3 0 0 3 3 3 1 CHAT domain PDEase_I PF00233.14 EIW70221.1 - 6.8e-43 147.1 0.0 1.2e-38 133.1 0.0 2.5 2 1 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase ADH_zinc_N PF00107.21 EIW70223.1 - 5.7e-26 90.5 0.0 8.5e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW70223.1 - 4.4e-08 34.0 0.0 7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW70223.1 - 0.00075 19.2 0.0 0.016 14.9 0.0 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EIW70223.1 - 0.025 14.4 0.3 0.042 13.7 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase FCH PF00611.18 EIW70224.1 - 1.1e-17 64.0 0.5 2.9e-17 62.6 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EIW70224.1 - 1e-10 40.8 0.0 2.2e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW70224.1 - 2.1e-09 36.7 0.0 5.3e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW70224.1 - 1.9e-07 30.4 0.0 4.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain HAMP PF00672.20 EIW70224.1 - 0.084 13.0 0.1 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 HAMP domain DUF4200 PF13863.1 EIW70224.1 - 0.78 9.6 6.3 4.6 7.2 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) RRF PF01765.14 EIW70224.1 - 2.3 7.6 5.9 3 7.2 0.1 2.7 1 1 2 3 3 3 0 Ribosome recycling factor Aminotran_3 PF00202.16 EIW70225.1 - 2.7e-38 131.7 0.0 7.5e-20 71.0 0.0 3.2 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EIW70225.1 - 6.3e-24 84.6 0.0 1.2e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Vps16_C PF04840.7 EIW70226.1 - 5e-83 278.6 0.0 6.7e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 EIW70226.1 - 5.2e-72 242.6 0.0 7.6e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region TPR_7 PF13176.1 EIW70226.1 - 0.19 11.6 6.9 0.12 12.2 0.4 3.5 2 2 0 2 2 2 0 Tetratricopeptide repeat Nucleoside_tran PF01733.13 EIW70227.1 - 2.3e-31 109.1 11.1 1.3e-28 100.0 1.3 2.2 1 1 1 2 2 2 2 Nucleoside transporter FUSC-like PF12805.2 EIW70227.1 - 5.3 5.8 7.1 11 4.8 4.9 1.5 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS RNA_pol_Rpb4 PF03874.11 EIW70229.1 - 6e-13 48.8 0.3 9.7e-13 48.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ank_2 PF12796.2 EIW70230.1 - 1.2e-19 70.4 0.1 1.6e-08 34.7 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIW70230.1 - 1.6e-17 62.2 0.2 5.2e-08 32.3 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIW70230.1 - 6.9e-14 51.5 0.6 2.9e-06 27.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW70230.1 - 1.2e-13 51.1 2.0 2.3e-06 27.9 0.1 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW70230.1 - 9.3e-12 43.9 0.6 0.0014 18.6 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 EIW70230.1 - 0.00023 20.7 0.1 0.0028 17.2 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain Spc7 PF08317.6 EIW70230.1 - 0.019 13.6 2.7 0.036 12.7 1.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein MamL-1 PF09596.5 EIW70230.1 - 0.085 12.6 2.3 0.15 11.9 0.8 2.1 2 0 0 2 2 2 0 MamL-1 domain IncA PF04156.9 EIW70230.1 - 2.5 7.6 5.8 5.1 6.6 4.0 1.5 1 0 0 1 1 1 0 IncA protein DNA_pol_E_B PF04042.11 EIW70231.1 - 8.6e-40 136.2 0.0 1.2e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CybS PF05328.7 EIW70232.1 - 1.1e-46 157.8 0.0 1.3e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 CybS Kinesin PF00225.18 EIW70234.1 - 2.6e-111 371.5 0.2 2.6e-111 371.5 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain Peptidase_C78 PF07910.8 EIW70235.1 - 0.12 11.4 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C78 ATG_C PF09333.6 EIW70236.1 - 1.2e-33 115.2 0.1 2.8e-33 113.9 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EIW70236.1 - 2.3e-10 40.0 0.0 6e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 EIW70236.1 - 2e-09 37.2 1.1 8.2e-09 35.2 0.7 2.1 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif Pkinase PF00069.20 EIW70237.1 - 1.4e-59 201.3 0.0 1.7e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW70237.1 - 2.3e-24 85.8 0.0 3.2e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW70237.1 - 5.4e-06 25.5 0.0 1.2e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIW70237.1 - 0.0056 16.4 0.0 0.024 14.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW70237.1 - 0.006 16.1 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3692 PF12469.3 EIW70238.1 - 0.02 15.1 0.0 0.027 14.6 0.0 1.3 1 1 0 1 1 1 0 CRISPR-associated protein MIF4G_like PF09088.6 EIW70239.1 - 1.2e-64 217.3 0.0 1.9e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EIW70239.1 - 2.8e-46 157.8 0.0 3.8e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 MIF4G like SlyX PF04102.7 EIW70239.1 - 0.11 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 SlyX DUF3741 PF12552.3 EIW70239.1 - 0.12 12.1 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) RRM_6 PF14259.1 EIW70240.1 - 1.3e-06 28.2 0.0 5.9e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW70240.1 - 0.0028 17.2 0.0 0.047 13.3 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rota_NS26 PF01525.11 EIW70240.1 - 0.018 14.8 0.6 0.032 14.0 0.4 1.4 1 0 0 1 1 1 0 Rotavirus NS26 Sel1 PF08238.7 EIW70242.1 - 3.9e-14 52.7 11.7 3.2e-06 27.6 0.2 5.7 5 0 0 5 5 5 3 Sel1 repeat TPR_2 PF07719.12 EIW70242.1 - 0.0028 17.4 3.4 0.037 13.9 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW70242.1 - 0.052 14.2 1.0 11 6.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_2b PF00587.20 EIW70244.1 - 2.1e-43 147.8 0.0 3.3e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIW70244.1 - 1.2e-19 70.0 0.6 2.6e-19 68.9 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EIW70244.1 - 2.4e-14 52.8 0.0 5.4e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 EIW70244.1 - 4.2e-10 39.3 0.0 7.5e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TPR_11 PF13414.1 EIW70245.1 - 2.9e-29 100.5 32.8 7.2e-09 35.1 0.0 11.2 10 4 4 14 14 14 7 TPR repeat TPR_1 PF00515.23 EIW70245.1 - 8e-25 85.3 7.5 0.0045 16.5 0.2 10.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.12 EIW70245.1 - 2.1e-22 77.1 26.1 0.00082 19.1 0.0 14.4 15 1 1 16 16 16 6 Tetratricopeptide repeat TPR_12 PF13424.1 EIW70245.1 - 6.3e-15 54.8 43.2 2.4e-08 33.7 1.9 11.9 9 3 3 12 12 12 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW70245.1 - 1.3e-13 51.0 54.6 0.00026 21.2 0.0 10.8 10 1 2 12 12 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 EIW70245.1 - 1.4e-13 49.5 6.3 0.44 10.4 0.0 10.0 10 1 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIW70245.1 - 1.5e-12 46.9 63.6 0.00057 20.2 0.0 15.1 11 4 5 16 16 15 5 Tetratricopeptide repeat TPR_7 PF13176.1 EIW70245.1 - 6.7e-12 44.2 21.9 0.0092 15.7 0.3 11.3 12 1 0 12 12 11 3 Tetratricopeptide repeat TPR_6 PF13174.1 EIW70245.1 - 1e-11 44.4 33.7 0.00028 21.1 0.0 12.2 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIW70245.1 - 4.6e-10 38.9 10.8 4.8 7.6 0.0 12.4 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIW70245.1 - 9.6e-09 35.6 13.7 5e-05 23.8 1.1 13.0 9 6 5 15 15 12 4 Tetratricopeptide repeat TPR_4 PF07721.9 EIW70245.1 - 0.64 10.6 0.0 0.64 10.6 0.0 9.4 11 0 0 11 11 7 0 Tetratricopeptide repeat TPR_3 PF07720.7 EIW70245.1 - 4.9 7.0 5.8 3.6 7.5 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3753 PF12575.3 EIW70246.1 - 0.07 12.9 0.3 0.29 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Arm_2 PF04826.8 EIW70248.1 - 0.14 11.2 0.8 0.26 10.3 0.3 1.6 2 0 0 2 2 2 0 Armadillo-like Histone PF00125.19 EIW70249.1 - 3.1e-30 104.1 0.6 4.9e-30 103.4 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW70249.1 - 2.7e-05 24.2 0.1 4.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIW70249.1 - 0.0083 16.1 1.0 0.0092 16.0 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIW70249.1 - 0.011 15.0 1.8 0.014 14.6 1.3 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EIW70249.1 - 0.081 12.6 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated BING4CT PF08149.6 EIW70250.1 - 7.9e-32 108.6 0.0 3.6e-31 106.5 0.0 2.2 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 EIW70250.1 - 8.5e-09 34.9 1.8 4.1e-07 29.6 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EIW70250.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Histone PF00125.19 EIW70251.1 - 2.7e-26 91.4 0.0 3.5e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW70251.1 - 0.00031 20.7 0.0 0.00041 20.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIW70252.1 - 2.7e-21 75.4 0.3 4e-21 74.9 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW70252.1 - 6.2e-07 29.3 0.1 1.2e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIW70252.1 - 0.00046 20.4 0.0 0.00072 19.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.6 EIW70252.1 - 0.019 14.3 0.1 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein eIF-4B PF06273.6 EIW70252.1 - 2.4 6.7 5.5 1.4 7.5 2.6 1.4 1 1 1 2 2 2 0 Plant specific eukaryotic initiation factor 4B Histone PF00125.19 EIW70253.1 - 1.1e-18 67.0 0.0 1.5e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW70253.1 - 0.06 13.4 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone F_bP_aldolase PF01116.15 EIW70254.1 - 2.1e-91 306.0 0.0 2.3e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.6 EIW70254.1 - 0.083 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Torsin WD40 PF00400.27 EIW70255.1 - 1.4e-26 91.3 9.9 1.3e-08 34.3 0.3 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Sec23_trunk PF04811.10 EIW70256.1 - 3.3e-71 239.5 0.0 1.3e-70 237.5 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIW70256.1 - 2.9e-24 84.4 0.3 1.4e-23 82.2 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EIW70256.1 - 1.2e-17 63.2 4.9 2.1e-17 62.3 3.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EIW70256.1 - 2.4e-14 53.5 0.0 6.6e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EIW70256.1 - 4.1e-08 32.8 0.0 7.9e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 EIW70256.1 - 2.3e-06 27.3 0.1 4.5e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 WW domain VWA_2 PF13519.1 EIW70256.1 - 0.01 15.9 1.1 0.016 15.2 0.1 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain HLH PF00010.21 EIW70258.1 - 2.3e-09 36.7 0.0 9.1e-09 34.8 0.0 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DDE_1 PF03184.14 EIW70259.1 - 1.6e-36 125.4 0.0 2.1e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW70259.1 - 1.7e-06 27.8 0.0 1.1e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW70259.1 - 8.3e-06 25.5 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF2296 PF10058.4 EIW70260.1 - 7.7e-15 54.3 0.1 1.2e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DNA_pol_A PF00476.15 EIW70261.1 - 3.5e-82 276.0 0.0 1.1e-81 274.4 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family A UPF0220 PF05255.6 EIW70263.1 - 2.6e-47 160.1 0.0 3.2e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Utp14 PF04615.8 EIW70264.1 - 3.5e-149 498.2 53.2 3.8e-87 293.1 23.1 3.1 2 1 1 3 3 3 2 Utp14 protein ArsB PF02040.10 EIW70265.1 - 8.8e-15 54.5 22.1 2.2e-11 43.4 4.8 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein Methyltransf_4 PF02390.12 EIW70266.1 - 4.2e-51 172.7 0.0 1.1e-38 132.2 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_26 PF13659.1 EIW70266.1 - 0.0011 18.9 0.0 0.0026 17.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW70266.1 - 0.006 17.0 0.0 0.03 14.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIW70266.1 - 0.0086 15.4 0.0 0.55 9.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EIW70266.1 - 0.0088 16.6 0.0 0.045 14.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW70266.1 - 0.021 15.1 0.0 0.073 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIW70266.1 - 0.11 12.9 0.0 12 6.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain DUF1713 PF08213.6 EIW70267.1 - 2e-07 30.5 17.2 3.8e-07 29.5 12.0 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) ATP-synt_DE_N PF02823.11 EIW70268.1 - 8.8e-19 67.0 0.1 1.4e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain WD40 PF00400.27 EIW70270.1 - 1.3e-11 43.8 2.8 0.017 15.0 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat GATA PF00320.22 EIW70270.1 - 6.1e-10 38.2 2.1 1.2e-09 37.2 1.4 1.6 1 0 0 1 1 1 1 GATA zinc finger Nop14 PF04147.7 EIW70270.1 - 1.9 6.3 35.0 2.8 5.7 24.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF3292 PF11696.3 EIW70271.1 - 2.1 6.0 6.2 0.55 8.0 2.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) tRNA-synt_2b PF00587.20 EIW70272.1 - 6.4e-24 84.4 0.0 8.9e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EIW70272.1 - 3e-07 30.4 6.4 3.2e-07 30.3 1.1 2.3 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EIW70272.1 - 0.81 9.2 4.9 0.18 11.4 1.2 1.5 2 0 0 2 2 2 0 IncA protein tRNA_anti-codon PF01336.20 EIW70273.1 - 0.0033 17.2 0.1 0.008 16.0 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SURF1 PF02104.10 EIW70274.1 - 2.3e-41 141.9 0.0 2.8e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 SURF1 family GPI-anchored PF10342.4 EIW70275.1 - 1.9e-09 37.8 3.2 1.9e-09 37.8 2.2 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Herpes_UL32 PF06070.6 EIW70275.1 - 0.26 9.6 3.2 0.33 9.3 2.2 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF3605 PF12239.3 EIW70276.1 - 7e-18 64.9 2.8 1.1e-06 28.5 0.3 3.6 4 0 0 4 4 4 3 Protein of unknown function (DUF3605) JmjC PF02373.17 EIW70278.1 - 6.4e-13 48.9 0.0 1.3e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARF7EP_C PF14949.1 EIW70278.1 - 0.23 11.8 3.5 0.31 11.4 0.1 2.6 2 0 0 2 2 2 0 ARF7 effector protein C-terminus zf-C5HC2 PF02928.11 EIW70278.1 - 0.44 10.6 4.8 0.86 9.7 3.3 1.5 1 0 0 1 1 1 0 C5HC2 zinc finger zf-AN1 PF01428.11 EIW70278.1 - 1.6 8.6 8.7 4.1 7.3 6.0 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger IBR PF01485.16 EIW70278.1 - 2.9 7.8 7.3 8.5 6.3 4.9 1.9 1 1 0 1 1 1 0 IBR domain DUF3915 PF13054.1 EIW70279.1 - 0.017 15.0 0.9 0.017 15.0 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) XPG_I PF00867.13 EIW70280.1 - 4.1e-25 87.6 0.0 8e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EIW70280.1 - 8.1e-23 80.6 0.0 2.1e-22 79.2 0.0 1.7 2 0 0 2 2 1 1 XPG N-terminal domain TPR_2 PF07719.12 EIW70280.1 - 4.2e-05 23.1 0.0 9.9e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat 5_3_exonuc PF01367.15 EIW70280.1 - 6.2e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 EIW70280.1 - 0.00027 20.5 0.0 0.00049 19.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_8 PF13181.1 EIW70280.1 - 0.0035 17.0 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIW70280.1 - 0.0035 16.9 0.1 0.0067 16.0 0.1 1.4 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 EIW70280.1 - 0.01 16.4 0.1 0.03 14.9 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF99 PF01949.11 EIW70280.1 - 0.027 13.5 0.1 0.84 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF99 TPR_12 PF13424.1 EIW70280.1 - 0.038 13.9 0.1 0.069 13.1 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW70280.1 - 0.038 14.4 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW70280.1 - 0.041 13.5 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EIW70280.1 - 0.043 13.9 0.2 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIW70280.1 - 0.056 13.2 0.1 0.16 11.8 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.13 EIW70280.1 - 0.06 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Peptidase_C14 PF00656.17 EIW70281.1 - 1.4e-65 221.4 0.0 1.8e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain zf-CCHC PF00098.18 EIW70282.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW70282.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW70282.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.18 EIW70283.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW70283.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW70283.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) PepSY_2 PF13670.1 EIW70284.1 - 0.093 12.6 0.6 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain BUD22 PF09073.5 EIW70284.1 - 0.85 8.6 3.1 1.3 8.0 2.1 1.2 1 0 0 1 1 1 0 BUD22 adh_short PF00106.20 EIW70287.1 - 1.4e-28 99.9 0.9 1.8e-28 99.5 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW70287.1 - 1.2e-25 90.6 0.0 1.6e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW70287.1 - 1.4e-09 37.8 0.1 1.4e-09 37.8 0.1 1.5 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.13 EIW70287.1 - 0.018 14.7 0.2 0.04 13.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dus PF01207.12 EIW70288.1 - 2.5e-51 174.3 0.0 4.2e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EIW70288.1 - 5e-08 32.4 9.7 0.00023 20.7 0.1 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ShK PF01549.19 EIW70288.1 - 0.12 12.7 1.9 17 5.8 0.0 2.6 2 0 0 2 2 2 0 ShK domain-like LRR_6 PF13516.1 EIW70289.1 - 4.9e-09 35.3 14.1 0.035 14.1 0.1 7.4 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 EIW70289.1 - 1.9e-07 30.5 13.9 0.00015 21.3 1.7 5.2 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIW70289.1 - 0.0018 18.0 10.7 14 6.2 0.0 7.5 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_7 PF13504.1 EIW70289.1 - 0.94 9.9 14.2 56 4.6 0.1 7.3 8 0 0 8 8 8 0 Leucine rich repeat HSF_DNA-bind PF00447.12 EIW70290.1 - 1.3e-33 115.2 0.5 2.5e-33 114.3 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Rab5-bind PF09311.6 EIW70290.1 - 0.034 14.0 0.5 0.06 13.2 0.3 1.3 1 0 0 1 1 1 0 Rabaptin-like protein HpcH_HpaI PF03328.9 EIW70291.1 - 6.6e-31 106.9 0.0 8.3e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TauD PF02668.11 EIW70292.1 - 2.4e-50 171.6 0.1 3e-50 171.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EIW70293.1 - 2.3e-27 95.6 24.7 3.9e-27 94.8 17.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF485 PF04341.7 EIW70293.1 - 4.9 6.9 8.9 3.8 7.2 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function, DUF485 TauD PF02668.11 EIW70294.1 - 6.5e-51 173.4 0.0 8.4e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EamA PF00892.15 EIW70296.1 - 4.4e-25 88.1 79.5 1.2e-07 31.8 7.5 4.5 4 0 0 4 4 4 4 EamA-like transporter family EmrE PF13536.1 EIW70296.1 - 0.00035 20.7 8.2 0.00035 20.7 5.7 4.9 4 1 0 4 4 4 2 Multidrug resistance efflux transporter MRP-L27 PF09809.4 EIW70297.1 - 4e-06 26.4 0.2 5.2e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 TylF PF05711.6 EIW70297.1 - 0.031 13.3 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Nefa_Nip30_N PF10187.4 EIW70297.1 - 0.1 12.8 0.8 0.16 12.1 0.6 1.3 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 SNN_linker PF09050.5 EIW70297.1 - 0.13 11.7 2.1 0.32 10.5 1.4 1.7 1 0 0 1 1 1 0 Stannin unstructured linker Sec23_trunk PF04811.10 EIW70298.1 - 2.7e-70 236.4 0.0 4e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIW70298.1 - 2.2e-34 116.9 1.2 3.4e-34 116.3 0.2 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EIW70298.1 - 4.9e-31 107.0 0.2 9.1e-31 106.2 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EIW70298.1 - 5.4e-18 64.2 5.2 1.1e-17 63.3 3.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EIW70298.1 - 6.2e-14 51.4 0.0 1.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat SecY PF00344.15 EIW70299.1 - 1.7e-99 333.0 12.6 2.2e-99 332.6 8.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EIW70299.1 - 3.5e-19 67.9 0.2 1.5e-18 66.0 0.1 2.2 1 0 0 1 1 1 1 Plug domain of Sec61p URO-D PF01208.12 EIW70300.1 - 4.5e-117 390.7 0.0 5.2e-117 390.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF2638 PF10937.3 EIW70301.1 - 7.5e-20 72.0 1.2 9.2e-20 71.7 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Pex14_N PF04695.8 EIW70301.1 - 0.011 15.8 3.6 0.017 15.1 2.5 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.4 EIW70301.1 - 0.028 13.8 6.2 0.031 13.7 4.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pap_E4 PF02711.9 EIW70301.1 - 0.36 11.6 4.2 0.52 11.1 2.9 1.5 1 1 0 1 1 1 0 E4 protein PWI PF01480.12 EIW70303.1 - 1.4e-23 82.7 0.0 2e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 PWI domain Vfa1 PF08432.5 EIW70304.1 - 6.3e-21 75.2 10.7 6.1e-20 72.0 7.4 1.9 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CSTF2_hinge PF14327.1 EIW70305.1 - 4.1e-26 90.8 1.7 4.1e-26 90.8 1.2 2.4 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EIW70305.1 - 1.6e-20 72.5 0.1 2.3e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW70305.1 - 3.5e-18 65.3 0.0 6.7e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW70305.1 - 2.7e-09 36.7 0.0 4.3e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EIW70305.1 - 1.8e-05 23.8 2.0 6.1e-05 22.2 1.4 1.9 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal Sigma70_r4_2 PF08281.7 EIW70305.1 - 0.14 11.6 0.1 0.42 10.1 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 WD40 PF00400.27 EIW70306.1 - 5.7e-31 105.2 12.9 1.2e-10 40.8 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat LSM PF01423.17 EIW70307.1 - 3.9e-12 45.5 0.0 5e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain Arylsulfotran_2 PF14269.1 EIW70308.1 - 2.4e-56 191.0 5.4 3.5e-56 190.5 3.8 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Ribophorin_II PF05817.9 EIW70309.1 - 9e-06 24.1 0.1 9.1e-06 24.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II zf-CCHC PF00098.18 EIW70311.1 - 0.0023 17.8 1.9 0.0039 17.0 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW70311.1 - 0.051 13.3 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIW70313.1 - 0.0022 17.8 1.9 0.0041 16.9 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW70313.1 - 0.055 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle polyprenyl_synt PF00348.12 EIW70314.1 - 6.5e-48 162.8 0.0 8.2e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase 2-Hacid_dh_C PF02826.14 EIW70315.1 - 1.9e-36 124.8 0.1 1.6e-35 121.8 0.1 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EIW70315.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EIW70315.1 - 0.081 13.4 0.0 0.4 11.2 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold AdoHcyase_NAD PF00670.16 EIW70315.1 - 0.09 12.6 0.0 20 4.9 0.0 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 EIW70315.1 - 0.12 11.9 0.1 0.34 10.4 0.0 1.8 1 0 0 1 1 1 0 ACT domain RPAP2_Rtr1 PF04181.8 EIW70316.1 - 3.9e-14 52.4 0.0 7.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF4654 PF15547.1 EIW70316.1 - 2.3 8.5 7.1 0.23 11.7 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4654) CAF-1_p150 PF11600.3 EIW70319.1 - 0.0033 16.8 18.0 0.0049 16.2 12.5 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal eIF3_subunit PF08597.5 EIW70319.1 - 0.32 10.5 14.1 0.46 9.9 9.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RR_TM4-6 PF06459.7 EIW70319.1 - 0.78 9.5 9.5 0.98 9.2 6.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Striatin PF08232.7 EIW70319.1 - 1.5 9.1 15.7 5.3 7.3 10.8 1.8 1 1 0 1 1 1 0 Striatin family Borrelia_P83 PF05262.6 EIW70319.1 - 2.4 6.3 13.1 2.7 6.1 9.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1764 PF08576.5 EIW70319.1 - 5.6 7.7 13.4 13 6.6 9.3 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF2072 PF09845.4 EIW70319.1 - 8 6.3 7.5 16 5.4 5.2 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF2587 PF10759.4 EIW70320.1 - 0.048 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW70321.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW70321.1 - 0.33 11.1 7.9 0.089 13.0 3.3 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW70321.1 - 0.64 8.5 2.7 0.85 8.1 1.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) GST_N_3 PF13417.1 EIW70322.1 - 3.3e-09 36.8 0.0 6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW70322.1 - 0.00041 20.1 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW70322.1 - 0.0011 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW70322.1 - 0.0028 18.0 0.0 0.007 16.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RNA_pol_Rpb2_6 PF00562.23 EIW70323.1 - 1.6e-117 392.5 0.0 2.3e-117 392.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIW70323.1 - 4.9e-52 175.8 0.2 8.6e-52 175.0 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EIW70323.1 - 4.6e-27 94.0 0.1 1.2e-26 92.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EIW70323.1 - 1.7e-26 92.8 0.0 4.4e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EIW70323.1 - 7.8e-22 76.8 0.1 1.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EIW70323.1 - 2.8e-20 71.8 0.0 6e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EIW70323.1 - 3.9e-12 45.9 1.3 7.8e-12 44.9 0.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Pkinase PF00069.20 EIW70324.1 - 2.6e-68 229.9 0.0 3.2e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW70324.1 - 1.4e-27 96.4 0.0 1.9e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW70324.1 - 0.011 15.4 0.1 0.032 13.9 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EIW70324.1 - 0.047 12.7 0.0 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Patched PF02460.13 EIW70325.1 - 0.33 8.7 2.1 0.44 8.3 1.5 1.0 1 0 0 1 1 1 0 Patched family IGPS PF00218.16 EIW70326.1 - 1.6e-87 292.7 0.1 1.1e-86 289.9 0.0 2.3 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EIW70326.1 - 3.5e-49 167.0 0.0 2.5e-46 157.7 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EIW70326.1 - 5.8e-42 143.3 0.0 1.1e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIW70326.1 - 8.9e-07 28.5 0.2 4.1e-06 26.3 0.2 2.0 1 1 0 1 1 1 1 Peptidase C26 His_biosynth PF00977.16 EIW70326.1 - 0.0015 17.8 0.3 0.21 10.8 0.0 2.8 3 0 0 3 3 3 1 Histidine biosynthesis protein FMN_dh PF01070.13 EIW70326.1 - 0.0018 17.1 0.2 0.98 8.1 0.0 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase QRPTase_C PF01729.14 EIW70326.1 - 0.012 15.1 0.8 0.072 12.6 0.0 2.5 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain TMP-TENI PF02581.12 EIW70326.1 - 0.035 13.2 0.1 2.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI zf-ribbon_3 PF13248.1 EIW70328.1 - 0.27 10.4 2.9 0.28 10.4 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain AhpC-TSA PF00578.16 EIW70329.1 - 2e-25 88.8 0.0 2.3e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW70329.1 - 2.6e-14 52.9 0.0 2.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EIW70329.1 - 0.0056 16.6 0.0 0.0071 16.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme RNase_T PF00929.19 EIW70330.1 - 2.4e-16 60.4 0.0 2.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EIW70330.1 - 0.0027 17.2 0.0 0.0057 16.1 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease RNase_T PF00929.19 EIW70331.1 - 4.9e-13 49.6 0.0 6e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 Exonuclease UPF0223 PF05256.7 EIW70331.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) RNase_T PF00929.19 EIW70332.1 - 2.2e-16 60.5 0.0 2.9e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Clathrin_lg_ch PF01086.12 EIW70333.1 - 1.6e-35 123.0 5.6 7.9e-31 107.7 3.7 2.7 2 1 0 2 2 2 2 Clathrin light chain DUF3347 PF11827.3 EIW70333.1 - 0.093 12.7 1.1 0.13 12.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Peptidase_M24 PF00557.19 EIW70336.1 - 1.6e-38 132.3 0.0 1.9e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3684 PF12449.3 EIW70337.1 - 0 1099.2 0.0 0 1098.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c PF02518.21 EIW70337.1 - 0.00086 19.0 0.0 0.0032 17.1 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIW70337.1 - 0.042 13.4 0.0 0.16 11.6 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ECH PF00378.15 EIW70338.1 - 4.9e-26 91.3 0.0 1.4e-25 89.8 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EIW70338.1 - 1.6e-23 83.0 0.4 7e-23 81.0 0.1 2.1 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ORC5_C PF14630.1 EIW70339.1 - 3e-40 138.3 0.0 8.6e-40 136.9 0.0 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus DnaJ-X PF14308.1 EIW70340.1 - 1.7e-51 174.4 0.1 3.4e-51 173.4 0.0 1.5 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 EIW70340.1 - 5.4e-23 80.5 0.9 5.4e-23 80.5 0.6 2.6 3 0 0 3 3 3 1 DnaJ domain PIN_4 PF13638.1 EIW70341.1 - 5.9e-20 71.7 0.9 1e-19 70.9 0.1 1.9 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.4 EIW70341.1 - 1.3e-13 50.7 0.0 3.4e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain U79_P34 PF03064.11 EIW70345.1 - 0.5 9.8 4.4 0.65 9.4 3.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Spore_GerAC PF05504.6 EIW70346.1 - 0.025 14.3 1.1 0.2 11.3 0.1 2.0 1 1 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal Sorting_nexin PF03700.8 EIW70347.1 - 0.006 16.6 0.4 0.011 15.7 0.2 1.5 1 1 0 1 1 1 1 Sorting nexin, N-terminal domain Myb_DNA-binding PF00249.26 EIW70347.1 - 0.028 14.4 0.3 0.05 13.6 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rap1_C PF11626.3 EIW70347.1 - 0.034 14.0 0.1 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ndc1_Nup PF09531.5 EIW70347.1 - 0.15 10.4 1.3 0.14 10.5 0.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MAGE_N PF12440.3 EIW70347.1 - 0.39 11.0 9.1 0.56 10.5 6.3 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal V-SNARE_C PF12352.3 EIW70348.1 - 2.3e-16 59.6 0.2 4.7e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EIW70348.1 - 0.0004 20.0 0.0 0.0016 18.1 0.0 1.8 2 0 0 2 2 2 1 Sec20 Sigma70_r4 PF04545.11 EIW70348.1 - 0.047 13.0 0.1 0.11 11.7 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3317 PF11779.3 EIW70349.1 - 1e-14 53.6 2.4 1.4e-14 53.2 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Rer1 PF03248.8 EIW70350.1 - 1.1e-75 253.0 0.0 1.4e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Rer1 family DUF937 PF06078.6 EIW70350.1 - 0.031 14.5 0.0 7.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) P16-Arc PF04699.9 EIW70351.1 - 2e-46 157.7 0.0 2.2e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Ham1p_like PF01725.11 EIW70352.1 - 9.3e-49 165.3 0.1 2.2e-48 164.1 0.0 1.6 2 0 0 2 2 2 1 Ham1 family Wbp11 PF09429.5 EIW70352.1 - 4e-18 65.1 15.8 7.7e-18 64.2 11.0 1.5 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.2 EIW70352.1 - 5.2e-09 36.4 19.3 5.2e-09 36.4 13.4 3.8 3 1 0 3 3 3 1 mRNA biogenesis factor CMS1 PF14617.1 EIW70352.1 - 2.4 7.1 8.2 3.8 6.5 5.7 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit USP8_interact PF08941.5 EIW70353.1 - 0.0011 18.3 1.0 0.29 10.4 0.4 2.4 2 1 0 2 2 2 2 USP8 interacting DUF2587 PF10759.4 EIW70354.1 - 0.044 13.1 0.1 0.12 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Pex24p PF06398.6 EIW70357.1 - 0.016 14.0 4.3 0.035 12.8 2.9 1.6 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin UPF0183 PF03676.9 EIW70358.1 - 2.3e-18 65.9 0.0 1e-11 44.0 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0183) Spermine_synth PF01564.12 EIW70359.1 - 1.8e-06 27.1 0.0 3.7e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Spermine/spermidine synthase TPR_2 PF07719.12 EIW70360.1 - 2.1e-34 114.6 3.2 2.7e-07 30.0 0.0 8.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 EIW70360.1 - 2.2e-34 116.8 1.2 4.5e-12 45.4 0.3 6.5 4 2 5 9 9 9 6 TPR repeat TPR_1 PF00515.23 EIW70360.1 - 6.3e-31 104.6 1.8 1.8e-08 33.6 0.0 7.1 8 0 0 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EIW70360.1 - 1.8e-29 101.6 2.0 2.2e-14 53.3 0.0 5.4 3 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIW70360.1 - 1.6e-25 89.1 4.3 4.1e-07 30.4 0.1 6.7 6 1 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIW70360.1 - 2.2e-22 77.4 1.0 0.0019 18.6 0.0 8.3 6 1 4 10 10 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 EIW70360.1 - 1.2e-21 76.3 1.0 9.5e-06 25.4 0.0 6.0 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 EIW70360.1 - 5.7e-19 68.2 0.0 3e-05 24.2 0.0 6.5 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EIW70360.1 - 1.1e-17 62.3 0.0 0.0027 17.3 0.0 6.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIW70360.1 - 1.9e-14 52.5 0.0 0.038 14.1 0.0 6.3 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 EIW70360.1 - 5e-11 42.3 1.3 2.5 8.7 0.1 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIW70360.1 - 2.9e-07 30.2 7.6 0.049 13.4 0.0 5.1 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 EIW70360.1 - 1.7e-06 27.3 2.4 0.00016 20.8 0.3 3.4 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW70360.1 - 3.5e-05 23.2 1.3 29 4.7 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Sel1 PF08238.7 EIW70360.1 - 0.00039 20.9 3.0 0.68 10.6 0.0 4.4 4 0 0 4 4 3 1 Sel1 repeat SNAP PF14938.1 EIW70360.1 - 0.0023 17.1 1.3 0.68 9.0 0.5 3.2 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP BTAD PF03704.12 EIW70360.1 - 0.11 12.7 0.0 0.11 12.7 0.0 3.6 2 2 1 3 3 3 0 Bacterial transcriptional activator domain NARP1 PF12569.3 EIW70360.1 - 0.23 10.1 0.2 6.4 5.3 0.0 2.8 2 1 0 3 3 3 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 EIW70360.1 - 2.2 8.3 10.0 22 5.1 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat DASH_Dad2 PF08654.5 EIW70361.1 - 1.7e-19 69.7 0.0 2.2e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 XPG_N PF00752.12 EIW70362.1 - 1e-30 105.9 0.0 2.2e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EIW70362.1 - 3.8e-24 84.5 0.0 9.4e-24 83.2 0.0 1.7 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 EIW70362.1 - 0.0057 16.1 2.4 0.0057 16.1 1.7 3.7 3 0 0 3 3 3 1 Ubiquitin interaction motif Senescence PF06911.7 EIW70363.1 - 1.5e-32 112.7 4.3 3.4e-18 65.9 0.1 2.3 2 0 0 2 2 2 2 Senescence-associated protein tRNA_Me_trans PF03054.11 EIW70365.1 - 2.9e-93 312.2 0.0 4.9e-92 308.2 0.0 2.0 1 1 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 EIW70365.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.12 EIW70365.1 - 0.047 12.5 0.1 4.3 6.1 0.0 2.4 2 0 0 2 2 2 0 NAD synthase DUF3653 PF12375.3 EIW70365.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Phage protein Nro1 PF12753.2 EIW70366.1 - 0.0011 18.0 0.2 0.0017 17.4 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 DUF3841 PF12952.2 EIW70366.1 - 0.0011 18.4 0.1 0.0019 17.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3841) RXT2_N PF08595.6 EIW70366.1 - 0.021 14.6 0.0 0.85 9.4 0.0 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Spt5_N PF11942.3 EIW70366.1 - 0.051 14.1 5.3 0.12 13.0 3.6 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 EIW70366.1 - 0.065 12.7 0.9 0.082 12.4 0.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Bromodomain PF00439.20 EIW70367.1 - 2.5e-27 94.6 0.2 5.3e-27 93.5 0.2 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EIW70367.1 - 5e-10 39.3 0.4 1.1e-09 38.3 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW70367.1 - 7.8e-10 38.6 0.1 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIW70367.1 - 0.00091 18.9 0.0 0.0021 17.7 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIW70367.1 - 0.021 14.9 0.0 0.071 13.2 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pneumo_att_G PF05539.6 EIW70368.1 - 1.9 7.7 7.6 2.3 7.4 5.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SUZ PF12752.2 EIW70369.1 - 3.4e-11 43.4 1.1 3.4e-11 43.4 0.8 2.6 3 0 0 3 3 3 1 SUZ domain SIR2 PF02146.12 EIW70370.1 - 9.9e-35 119.8 0.0 1.6e-34 119.1 0.0 1.3 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.5 EIW70370.1 - 0.24 11.3 2.8 0.49 10.4 1.9 1.5 1 0 0 1 1 1 0 Zinc ribbon domain NDUF_B8 PF05821.6 EIW70373.1 - 2.6e-08 33.7 0.0 3.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) CRC_subunit PF08624.5 EIW70374.1 - 1.7e-39 134.9 0.0 2.8e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Cellulase PF00150.13 EIW70375.1 - 6.9e-09 35.3 6.3 7.6e-09 35.1 3.6 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF515 PF04415.7 EIW70375.1 - 2 6.5 13.2 3.1 5.9 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) zf-CCHC PF00098.18 EIW70378.1 - 7.9e-05 22.4 1.3 0.00016 21.4 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW70378.1 - 0.049 13.3 1.1 0.084 12.6 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EIW70378.1 - 0.084 12.5 0.6 0.084 12.5 0.4 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIW70378.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIW70378.1 - 0.12 11.8 1.3 0.22 11.0 0.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.3 EIW70378.1 - 0.13 12.1 5.4 0.11 12.4 1.8 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Fungal_trans PF04082.13 EIW70383.1 - 7.8e-20 70.8 1.4 1.9e-19 69.6 1.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW70383.1 - 0.00012 21.8 8.3 0.00026 20.8 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPG48 PF14764.1 EIW70383.1 - 0.028 12.9 0.0 0.043 12.3 0.0 1.2 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking IPPT PF01715.12 EIW70385.1 - 3e-33 114.9 0.0 1.8e-20 73.0 0.1 2.6 3 0 0 3 3 3 2 IPP transferase AAA_16 PF13191.1 EIW70385.1 - 0.00094 19.2 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EIW70385.1 - 0.0013 19.5 0.0 0.0027 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 EIW70385.1 - 0.0053 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EIW70385.1 - 0.017 15.4 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW70385.1 - 0.027 14.7 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 EIW70385.1 - 0.032 14.3 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIW70385.1 - 0.038 13.8 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EIW70385.1 - 0.042 13.0 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CobU PF02283.11 EIW70385.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase MobB PF03205.9 EIW70385.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_PrkA PF08298.6 EIW70385.1 - 0.1 11.2 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain UPF0079 PF02367.12 EIW70385.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EIW70385.1 - 0.12 12.0 0.0 0.78 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PWWP PF00855.12 EIW70387.1 - 7.4e-05 22.8 0.0 0.00018 21.6 0.0 1.7 1 1 0 1 1 1 1 PWWP domain PPI_Ypi1 PF07491.6 EIW70388.1 - 9.3e-24 82.8 0.8 9.3e-24 82.8 0.6 1.8 2 0 0 2 2 2 1 Protein phosphatase inhibitor CDC45 PF02724.9 EIW70388.1 - 0.038 12.0 1.1 0.045 11.7 0.7 1.0 1 0 0 1 1 1 0 CDC45-like protein MTBP_C PF14920.1 EIW70388.1 - 0.078 12.4 4.5 0.085 12.3 3.1 1.1 1 0 0 1 1 1 0 MDM2-binding AT_hook PF02178.14 EIW70389.1 - 1.4 8.8 27.0 4.1 7.3 2.1 3.6 3 0 0 3 3 3 0 AT hook motif Ferritin_2 PF13668.1 EIW70390.1 - 1.5e-23 83.2 0.7 2.1e-23 82.7 0.5 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF515 PF04415.7 EIW70390.1 - 8.2 4.5 26.0 0.13 10.4 5.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF515) ATP-synt_C PF00137.16 EIW70391.1 - 1.5e-26 92.0 31.1 5.4e-15 55.0 6.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C KRTAP PF11759.3 EIW70391.1 - 6.2 7.1 7.4 2.8 8.2 1.3 2.3 2 0 0 2 2 2 0 Keratin-associated matrix Cpn60_TCP1 PF00118.19 EIW70392.1 - 1.7e-142 475.4 2.5 2e-142 475.2 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HATPase_c PF02518.21 EIW70394.1 - 3.1e-16 59.0 0.1 5.9e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIW70394.1 - 9.2e-15 54.6 0.1 3.2e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EIW70394.1 - 1.4e-11 44.2 0.1 4.2e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EIW70394.1 - 6.5e-05 23.1 0.0 0.0085 16.2 0.0 3.0 2 1 0 2 2 2 1 GAF domain GAF_3 PF13492.1 EIW70394.1 - 0.00083 19.4 0.0 1.6 8.8 0.0 3.2 2 1 0 2 2 2 2 GAF domain Peptidase_M22 PF00814.20 EIW70395.1 - 1.9e-81 273.5 0.0 3.9e-81 272.4 0.0 1.5 1 1 0 1 1 1 1 Glycoprotease family AflR PF08493.5 EIW70395.1 - 0.14 11.1 2.6 0.2 10.6 1.8 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein Hexapep PF00132.19 EIW70396.1 - 7.5e-12 44.1 11.0 5e-07 28.9 2.2 4.9 3 1 2 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIW70396.1 - 0.00045 19.7 15.6 0.0087 15.6 4.3 3.9 3 1 2 5 5 5 5 Hexapeptide repeat of succinyl-transferase DUF4200 PF13863.1 EIW70397.1 - 0.21 11.5 35.1 0.052 13.5 2.9 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 EIW70397.1 - 0.27 11.6 14.7 3.7 7.9 0.7 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF972) CCDC92 PF14916.1 EIW70397.1 - 1.8 8.2 9.3 9.3 5.9 2.2 3.5 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DivIC PF04977.10 EIW70397.1 - 6.4 6.3 15.5 6.5 6.3 0.1 4.2 4 1 0 4 4 4 0 Septum formation initiator zf-CCCH_2 PF14608.1 EIW70398.1 - 5.3e-11 42.0 26.1 0.0004 20.2 0.6 4.7 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EIW70398.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) CcdA PF07362.7 EIW70398.1 - 0.11 12.4 0.4 0.2 11.5 0.3 1.3 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA Arm PF00514.18 EIW70399.1 - 4.5e-68 222.9 34.1 3.7e-13 48.7 0.1 12.0 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIW70399.1 - 6.2e-25 87.3 16.5 9.9e-07 28.9 0.2 7.4 2 2 5 7 7 7 7 HEAT repeats HEAT PF02985.17 EIW70399.1 - 2.6e-19 67.5 19.0 0.043 13.9 0.0 9.7 9 0 0 9 9 9 6 HEAT repeat HEAT_EZ PF13513.1 EIW70399.1 - 5.7e-16 58.4 10.2 0.0065 16.9 0.4 8.3 5 2 3 8 8 8 5 HEAT-like repeat Arm_2 PF04826.8 EIW70399.1 - 4.3e-13 48.9 6.5 2.9e-08 33.1 1.4 3.7 2 1 0 3 3 3 2 Armadillo-like KAP PF05804.7 EIW70399.1 - 3.1e-10 38.6 0.4 5.4e-10 37.8 0.2 1.3 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EIW70399.1 - 6.2e-09 35.3 3.1 0.00053 19.1 0.1 3.6 1 1 2 3 3 3 2 V-ATPase subunit H Adaptin_N PF01602.15 EIW70399.1 - 1.5e-08 33.4 13.2 2.1e-07 29.6 0.3 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.2 EIW70399.1 - 0.00059 19.7 1.5 0.89 9.3 0.1 3.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EIW70399.1 - 0.0022 18.3 0.1 2 8.8 0.0 3.4 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 EIW70399.1 - 0.0063 16.4 3.9 3.7 7.5 0.0 4.7 1 1 2 5 5 5 1 V-ATPase subunit H DUF383 PF04063.9 EIW70399.1 - 0.024 14.1 0.8 0.15 11.6 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF383) HEAT_PBS PF03130.11 EIW70399.1 - 0.027 14.9 10.0 67 4.3 0.0 7.3 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EIW70399.1 - 0.03 12.5 5.4 0.13 10.4 2.2 2.3 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit MFS_1 PF07690.11 EIW70400.1 - 2.2e-22 79.2 53.4 5.7e-22 77.9 34.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1673 PF07895.6 EIW70400.1 - 1.4 8.4 7.3 10 5.5 2.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) COPI_assoc PF08507.5 EIW70400.1 - 2.5 7.7 32.9 0.017 14.7 4.5 4.6 3 2 1 5 5 5 0 COPI associated protein Spc7 PF08317.6 EIW70401.1 - 0.0019 16.9 14.7 0.0019 16.9 10.2 3.1 2 1 2 4 4 4 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EIW70401.1 - 2.1 7.4 6.9 0.74 8.9 1.2 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 EIW70401.1 - 7.1 6.6 19.9 7 6.6 0.1 5.0 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) BAR PF03114.13 EIW70402.1 - 2e-43 148.5 0.9 2.9e-43 148.0 0.6 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EIW70402.1 - 3e-15 55.3 0.1 5.1e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW70402.1 - 9.6e-14 50.7 0.0 1.7e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW70402.1 - 7.6e-11 41.3 0.0 1.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4463 PF14703.1 EIW70402.1 - 0.016 15.6 1.0 0.048 14.1 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) MBOAT PF03062.14 EIW70403.1 - 1.3e-39 136.2 0.4 1.3e-39 136.2 0.3 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family UPF0093 PF03653.8 EIW70403.1 - 0.033 14.1 0.6 0.081 12.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) Vps53_N PF04100.7 EIW70404.1 - 5.7e-73 245.8 0.3 1e-72 245.0 0.2 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.8 EIW70404.1 - 1.4e-06 26.7 4.5 5.8e-06 24.6 0.0 2.7 3 0 0 3 3 3 2 Exocyst complex component Sec6 tRNA_lig_kinase PF08303.6 EIW70404.1 - 0.024 14.4 0.0 0.076 12.8 0.0 1.8 1 0 0 1 1 1 0 tRNA ligase kinase domain DUF1193 PF06702.7 EIW70404.1 - 0.32 10.3 3.6 8.6 5.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1193) DAO PF01266.19 EIW70405.1 - 2e-41 142.1 0.0 2.6e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW70405.1 - 2e-06 27.7 0.0 6e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW70405.1 - 0.00011 22.1 0.0 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW70405.1 - 0.00033 20.7 0.0 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW70405.1 - 0.00074 19.3 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIW70405.1 - 0.0013 19.0 0.0 0.004 17.5 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIW70405.1 - 0.0022 18.1 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EIW70405.1 - 0.0024 16.8 0.0 0.005 15.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.16 EIW70405.1 - 0.0029 17.4 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 EIW70405.1 - 0.0031 16.9 0.1 0.0078 15.6 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EIW70405.1 - 0.0039 16.3 0.0 0.0075 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EIW70405.1 - 0.01 15.2 0.0 0.041 13.2 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EIW70405.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EIW70405.1 - 0.019 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EIW70405.1 - 0.038 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 EIW70405.1 - 0.041 12.7 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A F420_oxidored PF03807.12 EIW70405.1 - 0.08 13.3 0.0 0.5 10.8 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EIW70405.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 EIW70405.1 - 0.15 10.4 0.0 0.53 8.6 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Med6 PF04934.9 EIW70406.1 - 3.2e-32 111.0 0.0 4.5e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component ubiquitin PF00240.18 EIW70407.1 - 8.2e-34 114.8 0.6 1.1e-33 114.4 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIW70407.1 - 4.2e-17 61.6 0.2 5.5e-17 61.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIW70407.1 - 3.6e-06 27.1 0.2 1.4e-05 25.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIW70407.1 - 0.0042 16.7 0.0 0.0052 16.4 0.0 1.1 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIW70407.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIW70407.1 - 0.012 15.8 0.1 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ribosomal_L40e PF01020.12 EIW70407.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L40e family DUF2870 PF11069.3 EIW70407.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Sigma70_ner PF04546.8 EIW70408.1 - 4.5 6.8 6.8 3.3 7.2 2.9 2.1 1 1 1 2 2 2 0 Sigma-70, non-essential region Svf1 PF08622.5 EIW70409.1 - 2e-76 257.0 0.0 2.3e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Svf1-like Steroid_dh PF02544.11 EIW70411.1 - 2.7e-23 82.4 1.7 6.8e-12 45.3 0.1 3.0 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EIW70411.1 - 5.6e-05 22.5 0.0 7.3e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) AAR2 PF05282.6 EIW70412.1 - 1.2e-51 175.7 0.0 1.9e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 AAR2 protein Cupin_8 PF13621.1 EIW70413.1 - 2.2e-23 83.0 0.0 2.6e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EIW70413.1 - 0.0026 17.9 0.0 0.039 14.1 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EIW70413.1 - 0.025 14.0 0.0 0.061 12.8 0.0 1.6 2 0 0 2 2 2 0 Cupin domain Sdh_cyt PF01127.17 EIW70414.1 - 5.1e-23 81.2 2.1 6.3e-23 80.9 1.4 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CBS PF00571.23 EIW70415.1 - 3.2e-25 87.6 4.9 1.3e-10 40.8 0.0 4.5 4 1 0 4 4 4 4 CBS domain SR-25 PF10500.4 EIW70418.1 - 0.0028 17.1 13.9 0.0028 17.1 9.6 2.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF2587 PF10759.4 EIW70418.1 - 0.017 14.4 0.1 0.054 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) BUD22 PF09073.5 EIW70418.1 - 0.81 8.6 9.4 1.7 7.6 6.5 1.4 1 0 0 1 1 1 0 BUD22 RNase_T PF00929.19 EIW70419.1 - 8.8e-29 100.8 0.0 1e-28 100.6 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Acetyltransf_1 PF00583.19 EIW70420.1 - 2e-07 30.9 0.0 3.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIW70420.1 - 1.1e-05 25.0 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EIW70420.1 - 4.1e-05 23.5 0.0 6.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW70420.1 - 0.00031 20.8 0.0 0.00039 20.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW70420.1 - 0.00072 19.7 0.0 0.00085 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW70420.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIW70420.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EIW70420.1 - 0.0027 17.6 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Inositol_P PF00459.20 EIW70421.1 - 3.7e-48 164.1 0.0 1.6e-47 162.0 0.0 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family HSP70 PF00012.15 EIW70422.1 - 8.3e-240 796.8 4.5 9.3e-240 796.6 3.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIW70422.1 - 4.7e-16 58.2 0.7 3.6e-15 55.3 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EIW70422.1 - 0.0022 16.8 0.8 0.014 14.2 0.2 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EIW70422.1 - 0.0033 17.0 0.0 0.0074 15.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 EIW70422.1 - 0.0036 16.3 0.0 0.0075 15.2 0.0 1.5 1 0 0 1 1 1 1 StbA protein BcrAD_BadFG PF01869.15 EIW70422.1 - 0.032 13.5 3.1 1.7 7.9 0.1 2.8 3 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family NAD_binding_6 PF08030.7 EIW70423.1 - 2.4e-25 89.2 0.0 3.7e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIW70423.1 - 1.2e-21 76.5 0.0 2.4e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIW70423.1 - 5.6e-16 58.7 10.4 5.6e-16 58.7 7.2 1.9 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EIW70423.1 - 0.00054 20.0 0.0 0.0015 18.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIW70423.1 - 0.0014 19.1 0.0 0.049 14.2 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain ARID PF01388.16 EIW70424.1 - 0.031 14.1 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain ALAD PF00490.16 EIW70425.1 - 1.2e-112 376.0 0.0 1.5e-112 375.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase AAA_25 PF13481.1 EIW70426.1 - 0.00032 20.1 0.0 0.062 12.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_35 PF14516.1 EIW70426.1 - 0.19 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Zn_clus PF00172.13 EIW70427.1 - 5.1e-06 26.2 5.2 9.2e-06 25.4 3.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIW70427.1 - 0.017 14.0 0.1 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Chromo PF00385.19 EIW70428.1 - 1.1e-11 44.1 0.0 2.1e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Proteasome PF00227.21 EIW70429.1 - 2.9e-36 124.5 0.0 3.4e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit AAA_25 PF13481.1 EIW70430.1 - 2.8e-11 43.2 0.2 5.9e-11 42.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 EIW70430.1 - 4e-08 32.4 0.0 5.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_22 PF13401.1 EIW70430.1 - 0.018 15.2 0.0 0.056 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EIW70430.1 - 0.04 13.6 0.5 0.13 12.0 0.3 1.9 1 1 0 1 1 1 0 Part of AAA domain RecA PF00154.16 EIW70430.1 - 0.051 12.6 0.6 2.7 6.9 0.1 2.1 2 0 0 2 2 2 0 recA bacterial DNA recombination protein KaiC PF06745.8 EIW70430.1 - 0.056 12.5 0.3 0.62 9.1 0.0 2.2 2 1 0 2 2 2 0 KaiC IstB_IS21 PF01695.12 EIW70430.1 - 0.1 12.0 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Lact_bio_phlase PF09508.5 EIW70430.1 - 0.18 9.3 0.0 0.27 8.8 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase HAD PF12710.2 EIW70431.1 - 2.6e-19 70.1 0.0 4.8e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIW70431.1 - 1.2e-18 66.9 0.0 2.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIW70431.1 - 6.8e-15 56.0 3.7 5.8e-13 49.7 2.6 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW70431.1 - 1.7e-12 47.1 0.0 7.5e-12 45.0 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIW70431.1 - 0.00021 20.9 0.1 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIW70431.1 - 0.0084 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DNA_topoisoIV PF00521.15 EIW70432.1 - 1.3e-129 432.7 0.3 2.9e-129 431.6 0.0 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EIW70432.1 - 1.6e-36 125.0 0.5 4.7e-36 123.6 0.4 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EIW70432.1 - 3.3e-14 52.6 0.0 1.5e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EIW70432.1 - 5.8e-09 35.6 0.0 1.9e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIW70432.1 - 2e-06 27.4 0.7 5e-06 26.2 0.5 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MIF4G PF02854.14 EIW70435.1 - 3.7e-48 163.7 0.0 4.9e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EIW70435.1 - 0.0057 16.3 0.0 0.05 13.3 0.0 2.4 3 0 0 3 3 3 1 MA3 domain RRM_1 PF00076.17 EIW70436.1 - 7.1e-08 31.9 0.0 2e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW70436.1 - 4.6e-06 26.5 0.0 7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW70436.1 - 0.0048 16.7 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MutS_V PF00488.16 EIW70437.1 - 1.9e-25 89.6 0.0 3.9e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V DUF4158 PF13700.1 EIW70437.1 - 0.025 14.0 0.4 0.052 13.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Phos_pyr_kin PF08543.7 EIW70438.1 - 6.1e-12 45.2 0.0 5.1e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase PfkB PF00294.19 EIW70438.1 - 2.1e-07 30.3 0.0 2.8e-05 23.4 0.0 2.5 2 1 1 3 3 3 2 pfkB family carbohydrate kinase COPIIcoated_ERV PF07970.7 EIW70439.1 - 2e-35 122.4 0.2 2.9e-35 121.9 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EIW70439.1 - 9e-21 73.6 0.4 2e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3285 PF11688.3 EIW70439.1 - 0.027 14.0 1.3 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) PIG-U PF06728.8 EIW70440.1 - 1.1e-92 310.8 22.1 1.3e-92 310.5 15.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Ufd2P_core PF10408.4 EIW70441.1 - 2.7e-179 597.4 0.1 3.2e-179 597.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EIW70441.1 - 9.1e-25 86.4 2.7 5.9e-24 83.8 0.4 2.8 2 0 0 2 2 2 1 U-box domain DUF3753 PF12575.3 EIW70441.1 - 0.56 10.0 3.2 0.37 10.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Helitron_like_N PF14214.1 EIW70442.1 - 0.074 12.7 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Bactofilin PF04519.8 EIW70443.1 - 0.0023 17.8 8.3 1.3 9.0 3.2 4.0 2 1 0 2 2 2 2 Polymer-forming cytoskeletal Yae1_N PF09811.4 EIW70443.1 - 0.092 12.2 4.3 1.3 8.6 0.1 2.9 2 1 0 2 2 2 0 Essential protein Yae1, N terminal zf-CCHC PF00098.18 EIW70445.1 - 0.0027 17.5 1.9 0.0047 16.7 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle UBN2_3 PF14244.1 EIW70446.1 - 0.00037 20.0 0.1 0.00044 19.8 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1043 PF06295.7 EIW70446.1 - 0.025 14.2 0.3 0.046 13.3 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF3716 PF12511.3 EIW70447.1 - 0.035 13.7 0.1 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Pkinase PF00069.20 EIW70448.1 - 6.5e-62 209.0 0.0 8.7e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW70448.1 - 2.9e-32 111.7 0.0 4.5e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW70448.1 - 0.024 13.6 0.1 0.048 12.6 0.1 1.5 1 1 0 1 1 1 0 Kinase-like FANCL_C PF11793.3 EIW70449.1 - 0.059 13.3 2.0 0.13 12.2 1.1 1.7 2 0 0 2 2 2 0 FANCL C-terminal domain zf-CSL PF05207.8 EIW70450.1 - 1.7e-24 85.0 0.5 2.8e-24 84.3 0.4 1.4 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 EIW70450.1 - 0.0024 17.4 0.5 0.0039 16.7 0.3 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIW70450.1 - 0.0081 15.8 0.7 0.014 15.1 0.5 1.4 1 0 0 1 1 1 1 zinc-ribbon domain Alpha-amylase_C PF02806.13 EIW70451.1 - 2.4e-23 82.0 0.0 5.1e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EIW70451.1 - 8.7e-18 64.7 0.0 7.8e-15 55.0 0.0 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EIW70451.1 - 2.1e-15 56.5 0.0 4.6e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.1 EIW70451.1 - 0.098 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Transket_pyr PF02779.19 EIW70453.1 - 1.5e-35 122.2 0.0 2.2e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIW70453.1 - 6e-21 74.6 0.0 5.5e-20 71.5 0.0 2.2 1 1 0 1 1 1 1 Transketolase, C-terminal domain HSP70 PF00012.15 EIW70454.1 - 1.9e-259 861.6 8.2 2.2e-259 861.4 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIW70454.1 - 5.6e-15 54.7 3.5 3.2e-12 45.6 1.2 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EIW70454.1 - 2.4e-06 27.3 0.5 0.2 11.5 0.0 3.7 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.11 EIW70454.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1748 PF08520.5 EIW70454.1 - 0.063 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Peptidase_M48 PF01435.13 EIW70455.1 - 1.6e-14 54.0 0.0 3.2e-14 53.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M48 adh_short PF00106.20 EIW70456.1 - 7.6e-14 51.9 0.1 4.6e-06 26.6 0.4 3.1 4 0 0 4 4 4 2 short chain dehydrogenase KR PF08659.5 EIW70456.1 - 4e-06 26.6 0.1 2.5e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW70456.1 - 0.00047 19.9 0.0 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIW70456.1 - 0.011 15.1 0.0 0.09 12.1 0.0 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW70456.1 - 0.027 14.4 0.2 0.063 13.2 0.2 1.6 1 0 0 1 1 1 0 NADH(P)-binding Lipase_GDSL_2 PF13472.1 EIW70457.1 - 1.9e-12 47.6 0.4 8e-12 45.6 0.3 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Methyltransf_23 PF13489.1 EIW70458.1 - 6.4e-21 74.7 0.0 1.4e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW70458.1 - 2.8e-13 50.1 0.0 6.1e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW70458.1 - 5.5e-12 45.5 0.0 4.2e-11 42.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW70458.1 - 4.9e-09 36.5 0.0 1.3e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW70458.1 - 7.9e-07 29.6 0.1 3.2e-05 24.4 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIW70458.1 - 2.9e-06 26.4 0.0 6.5e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EIW70458.1 - 4.2e-05 23.5 0.0 0.00032 20.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW70458.1 - 9.1e-05 22.7 0.0 0.00035 20.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW70458.1 - 0.00061 18.9 0.0 0.0043 16.2 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EIW70458.1 - 0.0027 17.0 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 EIW70458.1 - 0.033 13.2 0.0 0.071 12.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 EIW70458.1 - 0.034 13.5 0.0 0.065 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 EIW70458.1 - 0.039 14.7 0.0 0.093 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EIW70458.1 - 0.05 12.2 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.13 EIW70458.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_29 PF03141.11 EIW70458.1 - 0.15 10.4 0.0 0.46 8.7 0.0 1.6 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase LRR_6 PF13516.1 EIW70459.1 - 1.2e-07 30.9 14.7 0.042 13.9 0.1 7.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.2 EIW70459.1 - 2.6e-07 30.1 12.3 0.0013 18.2 0.4 4.5 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW70459.1 - 0.00012 21.7 11.4 0.86 9.4 0.0 4.7 3 1 2 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 EIW70459.1 - 0.1 12.6 14.7 2 8.7 0.1 6.0 7 1 0 7 7 7 0 Leucine Rich Repeat DUF3268 PF11672.3 EIW70459.1 - 0.23 11.5 2.3 0.26 11.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) LRR_7 PF13504.1 EIW70459.1 - 1.6 9.2 20.0 7.4 7.2 0.0 6.8 7 0 0 7 7 7 0 Leucine rich repeat rve PF00665.21 EIW70460.1 - 0.094 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Thymidylate_kin PF02223.12 EIW70462.1 - 2.1e-44 151.1 0.0 2.4e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 EIW70462.1 - 0.0066 15.6 0.3 0.017 14.3 0.0 1.7 2 1 0 2 2 2 1 Chromatin associated protein KTI12 ArgK PF03308.11 EIW70462.1 - 0.067 11.9 0.0 0.097 11.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.1 EIW70462.1 - 0.1 12.4 0.2 0.26 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain HhH-GPD PF00730.20 EIW70463.1 - 4.6e-16 59.0 0.0 1e-15 57.9 0.0 1.5 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein TetR_C PF02909.12 EIW70463.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain ABA_GPCR PF12430.3 EIW70464.1 - 2.7e-48 163.7 0.3 5.5e-48 162.7 0.2 1.5 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EIW70464.1 - 2.1e-12 46.8 0.0 5.5e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) ADH_zinc_N PF00107.21 EIW70465.1 - 8e-15 54.5 0.5 2.5e-14 52.9 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW70465.1 - 5.6e-08 32.5 0.0 3.7e-06 26.6 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain PAS_9 PF13426.1 EIW70466.1 - 4.9e-27 94.3 0.0 2e-15 57.0 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 EIW70466.1 - 7.3e-16 57.9 0.0 3.3e-09 36.5 0.0 3.5 3 1 0 3 3 3 3 PAS fold PAS_3 PF08447.6 EIW70466.1 - 2.6e-13 49.8 0.0 5.8e-11 42.3 0.0 3.2 4 0 0 4 4 4 1 PAS fold PAS_11 PF14598.1 EIW70466.1 - 5.1e-13 48.9 0.0 6.3e-09 35.7 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.5 EIW70466.1 - 0.00026 20.9 0.0 0.036 14.0 0.0 3.3 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.1 EIW70466.1 - 0.053 13.4 0.0 4.7 7.2 0.0 2.7 2 0 0 2 2 2 0 PAS domain GAS2 PF02187.12 EIW70467.1 - 1.6e-06 27.7 0.1 3.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Pepsin-I3 PF06394.8 EIW70467.1 - 0.11 12.1 0.1 0.38 10.4 0.0 1.8 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain SH3_9 PF14604.1 EIW70468.1 - 3.1e-11 42.6 0.1 5.4e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW70468.1 - 2e-09 36.7 0.2 3.6e-09 35.8 0.1 1.5 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIW70468.1 - 3.6e-05 23.1 0.0 5.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.4 EIW70468.1 - 0.065 13.2 6.1 0.097 12.7 4.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) zf-GRF PF06839.7 EIW70470.1 - 6.6e-08 32.3 1.1 1.1e-07 31.5 0.7 1.3 1 0 0 1 1 1 1 GRF zinc finger DivIC PF04977.10 EIW70470.1 - 0.0059 16.0 2.7 0.012 15.1 1.9 1.6 1 0 0 1 1 1 1 Septum formation initiator CAGE1 PF15066.1 EIW70470.1 - 0.01 14.3 1.1 0.014 13.8 0.8 1.2 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family ADIP PF11559.3 EIW70470.1 - 0.031 14.1 3.6 0.052 13.4 2.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.4 EIW70470.1 - 0.037 14.0 3.7 0.088 12.8 2.6 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 IncA PF04156.9 EIW70470.1 - 0.037 13.6 2.9 0.057 13.0 2.0 1.3 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EIW70470.1 - 0.1 12.8 6.1 0.13 12.5 3.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 EIW70470.1 - 0.83 9.4 13.4 0.15 11.9 5.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_2 PF07716.10 EIW70470.1 - 2 8.2 11.6 0.14 11.9 2.8 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 EIW70470.1 - 5 7.5 7.0 1.5 9.2 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Cauli_AT PF03233.8 EIW70470.1 - 6.7 6.4 7.2 16 5.1 0.6 2.2 1 1 1 2 2 2 0 Aphid transmission protein Peptidase_M16 PF00675.15 EIW70471.1 - 5.6e-16 58.6 0.1 9.6e-16 57.8 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIW70471.1 - 2.1e-09 37.2 0.0 5.3e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain K-cyclin_vir_C PF09080.5 EIW70471.1 - 0.013 15.7 2.8 0.015 15.5 0.6 2.2 2 0 0 2 2 2 0 K cyclin, C terminal Mito_carr PF00153.22 EIW70472.1 - 8.6e-34 115.1 0.1 4.1e-12 45.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein IMS PF00817.15 EIW70473.1 - 1.2e-34 119.2 0.2 1.6e-32 112.3 0.2 2.7 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EIW70473.1 - 1.4e-16 60.6 0.2 2.7e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EIW70473.1 - 1.1e-05 25.2 0.0 3e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif RNA_polI_A34 PF08208.6 EIW70475.1 - 0.012 15.2 0.1 0.012 15.2 0.1 4.0 3 1 1 4 4 4 0 DNA-directed RNA polymerase I subunit RPA34.5 Radical_SAM PF04055.16 EIW70476.1 - 1.6e-09 38.1 0.0 3.4e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Kinesin PF00225.18 EIW70477.1 - 8.2e-96 320.6 0.0 1.8e-95 319.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain TMF_DNA_bd PF12329.3 EIW70477.1 - 0.024 14.4 0.0 0.024 14.4 0.0 11.2 8 3 4 13 13 13 0 TATA element modulatory factor 1 DNA binding AAA_29 PF13555.1 EIW70478.1 - 0.032 13.7 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RHD3 PF05879.7 EIW70479.1 - 1.1e-238 793.9 0.0 2.1e-238 793.0 0.0 1.4 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EIW70479.1 - 5e-06 25.7 0.0 9.3e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EIW70479.1 - 3.1e-05 23.8 0.0 6.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EIW70479.1 - 4.8e-05 23.3 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW70479.1 - 0.00059 20.3 0.0 0.0015 19.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EIW70479.1 - 0.0021 18.0 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Abhydrolase_1 PF00561.15 EIW70480.1 - 1.2e-34 119.9 0.0 2.3e-34 118.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIW70480.1 - 3e-08 33.8 0.2 0.0062 16.4 0.0 2.3 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW70480.1 - 0.011 15.4 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family CDK2AP PF09806.4 EIW70481.1 - 8.2 6.6 14.9 1.5 9.0 7.6 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Homeobox PF00046.24 EIW70482.1 - 1.8e-11 43.4 1.1 4.4e-11 42.2 0.8 1.7 1 0 0 1 1 1 1 Homeobox domain SNF2_N PF00176.18 EIW70483.1 - 5.1e-62 209.3 0.0 9.2e-62 208.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EIW70483.1 - 2.1e-15 56.5 0.0 4.2e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EIW70483.1 - 1.2e-14 53.8 0.0 3.2e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EIW70483.1 - 7.2e-08 32.3 3.6 1.4e-07 31.3 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW70483.1 - 4.9e-07 29.2 4.4 4.9e-07 29.2 3.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW70483.1 - 1.8e-06 27.6 5.8 3.7e-06 26.6 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EIW70483.1 - 5.8e-06 26.0 3.1 5.8e-06 26.0 2.1 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIW70483.1 - 0.00013 21.6 2.5 0.00033 20.3 0.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EIW70483.1 - 0.00026 21.0 3.3 0.00056 19.9 2.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIW70483.1 - 0.00077 19.1 5.4 0.00077 19.1 3.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW70483.1 - 0.0021 17.7 3.9 0.0021 17.7 2.7 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EIW70483.1 - 0.0028 17.5 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-Apc11 PF12861.2 EIW70483.1 - 0.0036 17.1 0.7 0.0092 15.8 0.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 EIW70483.1 - 0.098 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.1 EIW70483.1 - 0.68 9.5 4.5 2 8.0 3.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain ubiquitin PF00240.18 EIW70484.1 - 2.5e-06 26.8 0.7 1.4e-05 24.4 0.5 1.9 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EIW70484.1 - 0.00023 21.3 0.3 0.00086 19.5 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EIW70484.1 - 0.0081 15.8 0.2 0.015 14.9 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Carb_kinase PF01256.12 EIW70485.1 - 1.3e-45 155.5 0.0 2.2e-45 154.8 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EIW70485.1 - 0.0029 16.8 0.0 0.0043 16.2 0.0 1.3 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase zf-CCHC PF00098.18 EIW70487.1 - 0.0029 17.4 2.2 0.0047 16.7 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW70487.1 - 0.019 14.6 1.0 0.054 13.1 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW70487.1 - 0.35 11.1 8.0 0.092 12.9 3.4 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW70487.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Paf67 PF10255.4 EIW70489.1 - 3.4e-136 454.3 0.0 7e-136 453.2 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase I-associated factor PAF67 TPR_1 PF00515.23 EIW70489.1 - 0.00096 18.6 0.0 0.0026 17.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIW70489.1 - 0.0026 17.5 0.0 0.0096 15.7 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIW70489.1 - 0.025 15.0 0.1 0.48 10.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW70489.1 - 0.066 13.0 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIW70489.1 - 0.068 13.1 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RF-1 PF00472.15 EIW70490.1 - 2.5e-22 78.8 0.4 2.5e-22 78.8 0.3 2.1 1 1 1 2 2 2 1 RF-1 domain TIP_N PF12457.3 EIW70490.1 - 0.022 14.8 4.5 0.022 14.8 3.1 1.8 3 0 0 3 3 3 0 Tuftelin interacting protein N terminal DUF1117 PF06547.7 EIW70490.1 - 0.39 10.8 3.1 0.22 11.6 0.4 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1117) FLO_LFY PF01698.11 EIW70490.1 - 6.3 5.5 9.6 7.4 5.3 6.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Prefoldin_2 PF01920.15 EIW70491.1 - 1.4e-19 69.8 6.0 1.6e-19 69.6 4.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit FTA4 PF13093.1 EIW70491.1 - 0.00059 19.3 4.7 0.00076 18.9 3.3 1.3 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Tox-URI2 PF15653.1 EIW70491.1 - 0.017 15.3 0.3 0.056 13.6 0.0 1.8 1 1 1 2 2 2 0 URI fold toxin 2 Latarcin PF10279.4 EIW70491.1 - 0.25 11.5 3.9 3.6 7.8 0.5 2.2 1 1 1 2 2 2 0 Latarcin precursor IncA PF04156.9 EIW70491.1 - 1.1 8.8 7.0 2 7.9 4.9 1.4 1 1 0 1 1 1 0 IncA protein UPF0449 PF15136.1 EIW70491.1 - 1.3 9.2 4.7 0.59 10.3 0.5 2.0 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 bZIP_1 PF00170.16 EIW70491.1 - 1.5 8.8 7.2 4.6 7.2 0.8 2.4 2 0 0 2 2 2 0 bZIP transcription factor TMF_DNA_bd PF12329.3 EIW70491.1 - 1.8 8.4 9.4 0.47 10.2 1.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Rho_Binding PF08912.6 EIW70491.1 - 5.1 7.4 7.9 0.74 10.1 1.1 2.3 2 1 0 2 2 2 0 Rho Binding CBS PF00571.23 EIW70492.1 - 1.4e-37 127.1 6.0 1.1e-08 34.7 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EIW70492.1 - 1.6e-05 24.4 0.2 5.9e-05 22.6 0.0 2.1 2 1 0 2 2 2 1 PB1 domain Ribosomal_S13 PF00416.17 EIW70493.1 - 1.5e-23 83.2 0.0 4e-23 81.8 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EIW70493.1 - 0.0034 16.0 0.0 0.0035 15.9 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DAO PF01266.19 EIW70496.1 - 1.9e-54 184.9 0.0 2.4e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW70496.1 - 2.7e-08 33.9 0.0 0.043 13.6 0.0 3.6 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW70496.1 - 2.9e-05 24.0 0.0 0.0002 21.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIW70496.1 - 0.00023 19.7 0.0 0.12 10.7 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EIW70496.1 - 0.00039 20.5 0.0 0.13 12.2 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW70496.1 - 0.0015 17.4 0.5 0.0089 14.9 0.1 2.1 2 1 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EIW70496.1 - 0.0053 16.5 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIW70496.1 - 0.011 14.8 0.0 0.91 8.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EIW70496.1 - 0.013 14.3 0.0 0.12 11.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EIW70496.1 - 0.025 14.9 0.1 0.24 11.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIW70496.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EIW70496.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 EIW70497.1 - 4.8e-11 42.5 0.0 1.1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EIW70497.1 - 1.4e-07 30.9 0.0 0.00011 21.3 0.0 2.7 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EIW70497.1 - 1.8e-05 24.9 0.0 0.09 12.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW70497.1 - 1.8e-05 24.5 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EIW70497.1 - 0.00047 19.1 0.0 0.0017 17.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIW70497.1 - 0.0042 16.2 0.0 0.007 15.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EIW70497.1 - 0.15 12.5 0.3 0.83 10.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cellulase PF00150.13 EIW70498.1 - 4.4e-08 32.6 0.0 9.7e-08 31.5 0.0 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LCAT PF02450.10 EIW70499.1 - 4.2e-74 249.8 0.1 2.5e-73 247.2 0.1 1.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EIW70499.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW70499.1 - 0.018 14.9 0.0 0.075 12.8 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EIW70499.1 - 0.025 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EIW70499.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein zf-CCHC PF00098.18 EIW70500.1 - 0.00072 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW70500.1 - 0.31 11.2 7.3 0.09 13.0 3.0 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW70500.1 - 0.63 8.5 2.3 0.84 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Mei5 PF10376.4 EIW70502.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein L31 PF09784.4 EIW70503.1 - 0.0036 17.3 0.0 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L31 DUF1133 PF06576.6 EIW70503.1 - 0.052 12.7 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) Med15_fungi PF05397.7 EIW70503.1 - 0.057 13.3 2.0 1.2 9.1 0.1 2.3 2 1 0 2 2 2 0 Mediator complex subunit 15 Baculo_PEP_C PF04513.7 EIW70503.1 - 0.2 11.4 2.5 1 9.1 1.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3610 PF12272.3 EIW70504.1 - 0.0045 16.6 0.2 0.0059 16.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3610) DUF4318 PF14201.1 EIW70504.1 - 0.06 13.1 0.2 0.7 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4318) Apelin PF15360.1 EIW70505.1 - 1.4 9.1 6.2 0.17 12.0 0.4 2.2 2 0 0 2 2 2 0 APJ endogenous ligand E1-E2_ATPase PF00122.15 EIW70506.1 - 1.2e-72 243.6 0.1 2.5e-72 242.6 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIW70506.1 - 8e-39 133.0 0.6 2.3e-38 131.5 0.4 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIW70506.1 - 1.5e-32 113.7 0.0 4.3e-32 112.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW70506.1 - 4.8e-18 66.0 0.0 9.2e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW70506.1 - 1.1e-14 54.0 0.0 2.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIW70506.1 - 1.6e-13 49.8 0.0 3.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIW70506.1 - 4e-06 26.5 0.6 0.00073 19.1 0.5 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.7 EIW70506.1 - 0.01 15.3 2.7 0.018 14.6 0.0 2.6 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC HMG_box PF00505.14 EIW70507.1 - 4.5e-18 65.2 5.4 7.8e-10 38.8 0.3 2.7 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW70507.1 - 4.2e-11 43.0 5.4 3.1e-06 27.4 0.3 2.5 2 0 0 2 2 2 2 HMG-box domain MFS_1 PF07690.11 EIW70508.1 - 2.4e-35 121.8 11.7 2.4e-35 121.8 8.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW70508.1 - 4.4e-05 22.2 13.4 0.00061 18.4 1.5 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.15 EIW70508.1 - 0.056 11.4 4.6 0.51 8.3 0.5 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Rtf2 PF04641.7 EIW70509.1 - 1.4e-61 208.0 0.0 1.5e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EIW70509.1 - 0.0003 20.2 0.7 0.14 11.6 0.0 2.9 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-ribbon_3 PF13248.1 EIW70509.1 - 0.0077 15.4 0.6 0.0077 15.4 0.4 1.8 2 0 0 2 2 2 1 zinc-ribbon domain zf-RING_UBOX PF13445.1 EIW70509.1 - 0.023 14.4 1.5 0.099 12.3 0.8 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zinc_ribbon_2 PF13240.1 EIW70509.1 - 0.03 13.8 0.7 0.18 11.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EIW70509.1 - 0.04 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIW70509.1 - 0.052 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 EIW70509.1 - 0.062 12.9 0.3 0.19 11.4 0.2 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type CpXC PF14353.1 EIW70509.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 CpXC protein ADK_lid PF05191.9 EIW70509.1 - 0.099 12.3 0.4 0.24 11.0 0.1 1.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid FYDLN_acid PF09538.5 EIW70509.1 - 0.16 12.5 0.1 0.46 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TFIID-18kDa PF02269.11 EIW70511.1 - 2.4e-06 27.2 0.1 2.4e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit COX5B PF01215.14 EIW70513.1 - 6.4e-37 126.2 0.0 7.4e-37 126.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb TF_Zn_Ribbon PF08271.7 EIW70513.1 - 0.01 15.1 0.2 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Aminotran_3 PF00202.16 EIW70515.1 - 2.1e-107 358.9 0.0 2.5e-107 358.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EIW70515.1 - 0.014 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW70515.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF3770 PF12603.3 EIW70516.1 - 0.08 12.0 1.3 2.4 7.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3770) Brevenin PF03032.10 EIW70516.1 - 0.7 9.7 4.3 1.1 9.1 3.0 1.2 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family GATA PF00320.22 EIW70517.1 - 3.8e-09 35.7 4.1 7.3e-09 34.8 2.9 1.5 1 0 0 1 1 1 1 GATA zinc finger ER_lumen_recept PF00810.13 EIW70518.1 - 1.2e-56 191.2 5.0 1.6e-56 190.9 3.5 1.1 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EIW70518.1 - 0.00019 20.9 2.1 1.9 8.1 0.0 4.2 3 1 1 4 4 4 3 PQ loop repeat DUF373 PF04123.8 EIW70518.1 - 0.19 10.6 2.7 3.4 6.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) E1-E2_ATPase PF00122.15 EIW70519.1 - 2.2e-22 79.2 0.0 7.9e-22 77.4 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EIW70519.1 - 1.3e-21 77.6 0.0 2.5e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW70519.1 - 1.8e-21 77.5 0.0 2e-20 74.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW70519.1 - 0.00054 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIW70519.1 - 0.014 15.0 0.0 0.035 13.6 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pro_CA PF00484.14 EIW70520.1 - 3.7e-37 127.6 0.0 4.6e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Daxx PF03344.10 EIW70522.1 - 5.4e-06 25.2 9.7 5.4e-06 25.2 6.7 2.4 2 1 1 3 3 3 1 Daxx Family DUF2587 PF10759.4 EIW70522.1 - 0.14 11.5 0.1 0.14 11.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2587) Nop14 PF04147.7 EIW70522.1 - 1.7 6.4 19.4 2.5 5.9 13.5 1.1 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.18 EIW70523.1 - 0.00015 21.5 1.1 0.00024 20.8 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIW70523.1 - 0.039 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW70523.1 - 0.041 14.0 5.5 0.076 13.2 3.8 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain zf-CCHC_5 PF14787.1 EIW70523.1 - 1.6 8.2 7.8 0.32 10.5 1.8 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 EIW70524.1 - 0.00015 21.5 2.0 0.00024 20.8 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIW70524.1 - 0.008 15.6 0.1 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW70524.1 - 0.51 10.6 8.7 0.087 13.0 3.5 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain GBP_C PF02841.9 EIW70524.1 - 2.6 7.1 7.2 0.37 9.9 2.3 1.5 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain zf-CCHC_5 PF14787.1 EIW70524.1 - 7.7 6.0 8.5 0.82 9.2 2.2 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DDE_1 PF03184.14 EIW70525.1 - 1.7e-13 50.2 1.1 2.4e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease DUF2587 PF10759.4 EIW70527.1 - 0.052 12.9 0.1 0.14 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW70528.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW70528.1 - 0.34 11.1 8.0 0.092 12.9 3.4 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW70528.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF3287 PF11690.3 EIW70529.1 - 0.034 14.2 0.7 1.4 9.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Cep57_CLD_2 PF14197.1 EIW70529.1 - 0.037 13.9 1.6 0.042 13.7 0.4 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF3175 PF11373.3 EIW70529.1 - 0.093 12.7 0.3 5.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3175) Osmo_CC PF08946.5 EIW70529.1 - 0.13 12.2 0.2 0.35 10.9 0.0 1.8 2 1 0 2 2 2 0 Osmosensory transporter coiled coil MTHFR PF02219.12 EIW70532.1 - 4.3e-104 347.6 0.0 5.7e-104 347.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Nuc_sug_transp PF04142.10 EIW70534.1 - 8.3e-72 241.2 3.1 1.1e-71 240.7 2.2 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EIW70534.1 - 4.4e-08 32.4 7.0 7.4e-08 31.6 4.9 1.4 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EIW70534.1 - 1.8e-07 31.3 0.4 1.8e-07 31.3 0.3 2.7 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EIW70534.1 - 6.9e-05 22.8 2.0 6.9e-05 22.8 1.4 3.1 2 2 1 3 3 3 1 EamA-like transporter family TPT PF03151.11 EIW70534.1 - 0.00013 21.6 14.4 0.00083 19.0 0.1 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family Spidroin_MaSp PF11260.3 EIW70534.1 - 0.14 12.2 1.2 0.37 10.9 0.0 2.3 3 0 0 3 3 3 0 Major ampullate spidroin 1 and 2 Neur PF00064.13 EIW70535.1 - 0.13 10.3 0.0 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 Neuraminidase Mg_trans_NIPA PF05653.9 EIW70537.1 - 8e-20 70.9 10.8 1e-09 37.8 1.7 2.3 2 1 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EIW70537.1 - 0.0012 19.0 21.7 0.0029 17.7 3.8 2.9 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 EIW70537.1 - 0.07 13.1 19.7 0.018 15.0 3.0 2.6 2 0 0 2 2 2 0 EamA-like transporter family ALG3 PF05208.8 EIW70538.1 - 6.2e-108 361.3 25.2 2.3e-107 359.4 17.5 1.8 1 1 0 1 1 1 1 ALG3 protein zf-CCHC PF00098.18 EIW70539.1 - 0.00023 20.9 1.3 0.00035 20.3 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW70539.1 - 0.06 13.0 0.5 0.2 11.3 0.4 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIW70539.1 - 0.12 12.1 1.3 0.25 11.0 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF2587 PF10759.4 EIW70540.1 - 0.035 13.5 0.1 0.097 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Nop14 PF04147.7 EIW70540.1 - 3.4 5.4 4.3 5 4.9 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.18 EIW70541.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW70541.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW70541.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW70542.1 - 0.045 13.1 0.1 0.12 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PepSY_2 PF13670.1 EIW70542.1 - 0.43 10.5 3.7 0.91 9.4 2.6 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain PsbQ PF05757.6 EIW70542.1 - 8.1 5.7 7.5 4.4 6.6 3.4 1.8 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) UBN2 PF14223.1 EIW70543.1 - 3.8e-05 23.4 0.0 7.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW70543.1 - 0.00012 21.7 0.0 0.02 14.4 0.0 2.5 3 0 0 3 3 3 2 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIW70543.1 - 0.008 15.7 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2385 PF09539.5 EIW70544.1 - 0.22 11.9 0.9 2.2 8.7 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2385) zf-PHD-like PF15446.1 EIW70547.1 - 0.15 11.3 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Utp11 PF03998.8 EIW70548.1 - 1.5e-61 208.3 11.1 1.7e-61 208.1 7.7 1.1 1 0 0 1 1 1 1 Utp11 protein DUF932 PF06067.6 EIW70548.1 - 0.051 12.8 2.2 0.33 10.2 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF932) ABC_membrane PF00664.18 EIW70549.1 - 3.7e-47 161.0 1.7 5.1e-47 160.5 1.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EIW70549.1 - 6.2e-31 107.5 0.0 1.6e-30 106.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EIW70549.1 - 0.0033 16.6 3.3 0.016 14.4 0.1 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EIW70549.1 - 0.0044 15.6 0.3 0.015 13.8 0.2 1.7 1 1 0 1 1 1 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 EIW70549.1 - 0.0069 15.8 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EIW70549.1 - 0.0097 15.3 0.1 0.6 9.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EIW70549.1 - 0.048 13.6 0.2 1 9.2 0.0 2.2 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EIW70549.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Y_phosphatase PF00102.22 EIW70551.1 - 1.2e-59 201.5 0.0 2.3e-52 177.6 0.0 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 EIW70551.1 - 4.7e-08 33.3 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EIW70551.1 - 0.0036 17.5 0.0 0.24 11.6 0.0 2.9 3 0 0 3 3 3 1 Tyrosine phosphatase family DSPc PF00782.15 EIW70551.1 - 0.007 15.9 0.2 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EIW70551.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate FMN_dh PF01070.13 EIW70553.1 - 3.4e-118 394.5 0.1 4.1e-118 394.2 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EIW70553.1 - 8.6e-06 24.9 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EIW70553.1 - 0.00028 19.8 0.0 0.00058 18.8 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Cyt-b5 PF00173.23 EIW70553.1 - 0.00089 19.0 0.3 0.0054 16.5 0.0 2.5 3 1 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.10 EIW70553.1 - 0.078 12.1 0.1 0.13 11.3 0.1 1.4 1 1 0 1 1 1 0 Nitronate monooxygenase FIVAR PF07554.8 EIW70554.1 - 0.0062 16.7 0.3 0.015 15.5 0.2 1.7 1 1 0 1 1 1 1 Uncharacterised Sugar-binding Domain Ferritin-like PF12902.2 EIW70554.1 - 0.066 12.8 0.3 0.076 12.5 0.2 1.0 1 0 0 1 1 1 0 Ferritin-like E3_binding PF02817.12 EIW70554.1 - 0.11 12.1 0.2 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 e3 binding domain DUF2457 PF10446.4 EIW70555.1 - 0.0069 15.1 1.4 0.011 14.4 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) F-box PF00646.28 EIW70555.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 F-box domain CENP-B_dimeris PF09026.5 EIW70555.1 - 6.9 6.9 10.5 16 5.8 7.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SNF2_N PF00176.18 EIW70556.1 - 1.2e-70 237.6 0.2 2e-70 236.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW70556.1 - 2.9e-14 52.6 0.0 6.6e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW70556.1 - 1.9e-08 34.3 0.0 1.9e-08 34.3 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIW70556.1 - 1.8e-06 27.5 0.0 3.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EIW70556.1 - 0.026 13.3 0.1 0.24 10.1 0.1 2.3 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 EIW70556.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 CAP_N PF01213.14 EIW70556.1 - 4 6.6 7.1 6.1 6.0 4.5 1.6 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Use1 PF09753.4 EIW70557.1 - 2.3e-06 27.2 0.9 2.9e-06 26.9 0.6 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF607 PF04678.8 EIW70557.1 - 0.025 14.5 0.2 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Prefoldin_2 PF01920.15 EIW70557.1 - 0.1 12.3 2.2 12 5.7 0.3 2.5 2 0 0 2 2 2 0 Prefoldin subunit RRM_1 PF00076.17 EIW70558.1 - 1.2e-30 104.9 0.1 6.6e-20 70.5 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW70558.1 - 1.2e-14 53.8 0.0 1.8e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW70558.1 - 2.2e-13 49.9 0.0 2.4e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EIW70558.1 - 0.0068 15.8 1.1 0.46 10.0 0.2 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 EIW70558.1 - 0.11 12.2 0.0 21 4.9 0.0 2.4 2 1 0 2 2 2 0 Limkain b1 CFEM PF05730.6 EIW70560.1 - 1.1e-06 28.3 9.6 1.7e-06 27.7 6.7 1.3 1 0 0 1 1 1 1 CFEM domain CFEM PF05730.6 EIW70561.1 - 2.2e-07 30.6 6.7 4e-07 29.7 4.6 1.4 1 0 0 1 1 1 1 CFEM domain Hamartin PF04388.7 EIW70561.1 - 2.8 6.4 20.6 3.7 6.1 14.3 1.1 1 0 0 1 1 1 0 Hamartin protein Glyco_transf_90 PF05686.7 EIW70562.1 - 4.1e-13 48.8 2.0 4e-12 45.5 0.2 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 Peptidase_C50 PF03568.12 EIW70562.1 - 0.0065 15.1 0.1 0.0098 14.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C50 TFIIS_C PF01096.13 EIW70563.1 - 1.9e-12 46.5 9.5 7.8e-12 44.6 1.0 2.8 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EIW70563.1 - 1.2e-09 37.7 3.9 1.2e-09 37.7 2.7 2.6 4 0 0 4 4 3 1 RNA polymerases M/15 Kd subunit DUF3268 PF11672.3 EIW70563.1 - 0.0014 18.6 4.5 0.2 11.7 0.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3268) GFA PF04828.9 EIW70563.1 - 0.0053 16.6 3.7 0.21 11.5 0.1 2.7 1 1 2 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EIW70563.1 - 0.013 15.2 9.5 0.13 12.1 0.7 2.7 2 1 0 2 2 2 0 Double zinc ribbon Terminase_GpA PF05876.7 EIW70563.1 - 0.014 13.8 0.0 0.019 13.3 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) C1_4 PF07975.7 EIW70563.1 - 0.036 14.0 10.2 1.2 9.1 0.5 3.1 2 1 1 3 3 3 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.1 EIW70563.1 - 0.051 13.8 0.8 0.051 13.8 0.5 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.2 EIW70563.1 - 0.094 12.5 9.3 0.18 11.6 1.7 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF2387 PF09526.5 EIW70563.1 - 0.1 12.5 3.3 0.6 10.0 0.3 2.4 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Crust_neurohorm PF01147.12 EIW70563.1 - 0.31 10.3 7.1 0.51 9.6 0.1 2.5 2 1 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family zf-H2C2_2 PF13465.1 EIW70563.1 - 0.31 11.3 5.2 17 5.9 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-FPG_IleRS PF06827.9 EIW70563.1 - 0.41 10.3 7.0 1.9 8.2 0.6 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DUF2296 PF10058.4 EIW70563.1 - 0.52 10.1 12.3 1 9.1 2.3 2.9 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-RING_3 PF14369.1 EIW70563.1 - 0.55 10.2 8.1 5 7.2 0.1 3.2 3 0 0 3 3 3 0 zinc-finger HypA PF01155.14 EIW70563.1 - 0.65 9.7 5.7 1 9.0 1.6 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1 PF03811.8 EIW70563.1 - 0.71 9.4 0.1 0.71 9.4 0.1 3.2 3 0 0 3 3 3 0 InsA N-terminal domain Lar_restr_allev PF14354.1 EIW70563.1 - 0.9 9.8 5.7 0.54 10.5 0.2 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar DUF2082 PF09855.4 EIW70563.1 - 1.8 8.4 6.0 1.8 8.4 0.1 2.8 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc_ribbon_6 PF14599.1 EIW70563.1 - 2 8.3 9.4 1.5 8.6 0.6 2.6 2 1 0 2 2 2 0 Zinc-ribbon Zn-ribbon_8 PF09723.5 EIW70563.1 - 2.1 8.3 9.7 4.7 7.2 0.1 3.7 4 0 0 4 4 4 0 Zinc ribbon domain PADR1 PF08063.7 EIW70563.1 - 2.6 7.5 8.3 2.7 7.4 0.3 3.0 2 1 0 2 2 2 0 PADR1 (NUC008) domain DnaJ_CXXCXGXG PF00684.14 EIW70563.1 - 3.5 7.7 6.7 0.52 10.4 0.2 2.4 2 1 0 2 2 2 0 DnaJ central domain C1_1 PF00130.17 EIW70563.1 - 4 7.2 9.2 2.7 7.7 0.1 3.1 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_RNApol_7kD PF03604.8 EIW70563.1 - 5 6.6 10.3 32 4.0 0.1 4.1 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Mut7-C PF01927.11 EIW70563.1 - 6.5 6.7 6.7 9.6 6.1 0.9 2.4 1 1 1 2 2 2 0 Mut7-C RNAse domain DUF3716 PF12511.3 EIW70563.1 - 7.2 6.2 9.9 6.1 6.5 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3716) VIT1 PF01988.14 EIW70564.1 - 6e-71 238.3 2.5 7.5e-71 237.9 1.7 1.1 1 0 0 1 1 1 1 VIT family RNB PF00773.14 EIW70565.1 - 2.7e-55 187.9 0.0 4.7e-55 187.1 0.0 1.4 1 0 0 1 1 1 1 RNB domain Ricin_B_lectin PF00652.17 EIW70566.1 - 8.1e-10 38.8 12.1 8.7e-06 25.7 0.3 3.5 1 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain AMP-binding PF00501.23 EIW70567.1 - 1.3e-86 290.6 0.0 1.6e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AAA PF00004.24 EIW70569.1 - 1.8e-42 144.6 0.0 3.8e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EIW70569.1 - 2.2e-25 88.2 0.0 6.5e-25 86.8 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EIW70569.1 - 2e-18 65.9 4.8 2e-18 65.9 3.3 2.2 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 EIW70569.1 - 1.1e-06 28.7 0.7 0.00028 21.0 0.1 2.9 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EIW70569.1 - 5.8e-06 26.0 0.0 3.3e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EIW70569.1 - 9.6e-06 25.1 0.0 4e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 EIW70569.1 - 1.1e-05 25.3 0.2 3.8e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIW70569.1 - 1.9e-05 23.8 0.0 3.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIW70569.1 - 2.5e-05 24.3 0.1 0.002 18.1 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EIW70569.1 - 2.7e-05 24.9 0.5 0.00011 22.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 EIW70569.1 - 7e-05 21.7 0.0 0.00013 20.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 EIW70569.1 - 0.00023 21.1 0.1 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EIW70569.1 - 0.00036 19.5 0.0 0.0012 17.7 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EIW70569.1 - 0.00037 20.3 0.0 0.001 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW70569.1 - 0.00066 19.8 0.4 0.01 16.0 0.0 2.7 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.1 EIW70569.1 - 0.00082 18.8 0.4 0.25 10.7 0.1 2.9 2 1 0 3 3 3 1 AAA domain NACHT PF05729.7 EIW70569.1 - 0.0034 17.0 0.1 0.26 10.9 0.0 2.8 2 1 1 3 3 3 1 NACHT domain AAA_24 PF13479.1 EIW70569.1 - 0.0054 16.3 0.2 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIW70569.1 - 0.0097 16.2 0.7 0.029 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EIW70569.1 - 0.017 14.9 0.3 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIW70569.1 - 0.02 14.6 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EIW70569.1 - 0.025 13.8 0.5 0.087 12.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein KAP_NTPase PF07693.9 EIW70569.1 - 0.025 13.5 0.6 3 6.7 0.0 2.8 2 1 1 3 3 3 0 KAP family P-loop domain Mg_chelatase PF01078.16 EIW70569.1 - 0.027 13.6 0.0 0.064 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EIW70569.1 - 0.027 13.5 0.1 0.27 10.2 0.1 2.4 1 1 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EIW70569.1 - 0.035 14.1 0.1 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain OGFr_N PF04664.8 EIW70569.1 - 0.038 13.3 0.4 0.07 12.4 0.2 1.4 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region Parvo_NS1 PF01057.12 EIW70569.1 - 0.049 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EIW70569.1 - 0.05 13.2 3.3 0.32 10.6 0.0 2.8 2 1 0 3 3 3 0 Archaeal ATPase KaiC PF06745.8 EIW70569.1 - 0.052 12.6 0.1 4.9 6.2 0.0 2.3 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.21 EIW70569.1 - 0.06 12.8 0.0 0.24 10.8 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.7 EIW70569.1 - 0.079 12.5 0.0 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.1 EIW70569.1 - 0.084 13.1 2.1 4.2 7.6 0.7 2.5 2 1 0 2 2 2 0 AAA domain Pet20 PF08692.5 EIW70569.1 - 0.1 12.5 0.2 0.28 11.1 0.1 1.7 2 0 0 2 2 1 0 Mitochondrial protein Pet20 Torsin PF06309.6 EIW70569.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Torsin Guanylate_kin PF00625.16 EIW70569.1 - 0.13 11.6 1.3 0.3 10.5 0.0 2.2 2 1 0 2 2 2 0 Guanylate kinase YliH PF10799.3 EIW70569.1 - 0.14 11.8 0.5 0.47 10.1 0.2 1.9 2 0 0 2 2 1 0 Biofilm formation protein (YliH/bssR) AAA_21 PF13304.1 EIW70569.1 - 0.41 10.5 2.9 3.5 7.5 0.0 2.8 2 1 0 3 3 3 0 AAA domain Methyltransf_23 PF13489.1 EIW70570.1 - 2.5e-05 24.0 0.0 5.2e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EIW70570.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Spt20 PF12090.3 EIW70571.1 - 7.5e-29 100.3 0.0 7.5e-29 100.3 0.0 3.0 2 2 0 2 2 2 1 Spt20 family Ndc1_Nup PF09531.5 EIW70571.1 - 1.2 7.4 2.6 1.5 7.1 1.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TctB PF07331.6 EIW70572.1 - 0.0093 15.6 0.2 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DUF2207 PF09972.4 EIW70572.1 - 0.081 11.5 0.8 0.11 11.0 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF872 PF05915.7 EIW70572.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) NICE-3 PF07406.6 EIW70572.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.6 1 1 0 1 1 1 0 NICE-3 protein DUF1469 PF07332.6 EIW70572.1 - 0.94 9.2 3.4 1.7 8.3 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Aminotran_3 PF00202.16 EIW70573.1 - 8.6e-103 343.7 0.0 1e-102 343.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EIW70573.1 - 0.0036 16.3 0.0 0.0057 15.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Citrus_P18 PF05520.6 EIW70574.1 - 0.087 12.3 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Citrus tristeza virus P18 protein TPR_2 PF07719.12 EIW70575.1 - 8.1e-12 44.1 1.9 0.0044 16.8 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIW70575.1 - 7.3e-10 38.3 3.7 8.3e-07 28.5 0.1 3.8 4 0 0 4 4 4 1 TPR repeat PB1 PF00564.19 EIW70575.1 - 1.5e-07 30.9 0.0 2.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.23 EIW70575.1 - 2.6e-06 26.8 4.1 0.51 10.0 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW70575.1 - 5.2e-06 26.2 0.9 0.00065 19.5 0.1 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIW70575.1 - 0.0025 17.4 0.7 4.4 7.3 0.0 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIW70575.1 - 0.0041 16.7 1.2 1.5 8.7 0.0 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIW70575.1 - 0.02 14.7 0.6 1.6 8.5 0.0 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Paf67 PF10255.4 EIW70575.1 - 0.03 13.2 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_19 PF14559.1 EIW70575.1 - 0.039 14.2 0.0 3.4 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIW70575.1 - 0.068 13.8 3.4 27 5.6 0.2 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIW70575.1 - 0.071 13.5 0.6 3.8 8.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW70575.1 - 0.23 12.1 1.6 45 5.0 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW70575.1 - 0.34 11.4 2.2 94 3.8 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Phage_holin_1 PF04531.8 EIW70577.1 - 0.15 12.1 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage holin Amidohydro_3 PF07969.6 EIW70580.1 - 8.4e-24 84.5 0.0 3.1e-23 82.6 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family D-aminoacyl_C PF07908.7 EIW70580.1 - 1.4e-14 53.0 0.0 2.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 D-aminoacylase, C-terminal region Amidohydro_5 PF13594.1 EIW70580.1 - 3.1e-10 39.7 0.0 7.9e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EIW70580.1 - 1.7e-09 38.1 0.1 0.00058 19.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EIW70580.1 - 6.2e-05 22.8 0.0 0.035 13.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family D-ser_dehydrat PF14031.1 EIW70581.1 - 7e-22 77.4 0.0 1.4e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EIW70581.1 - 5e-15 55.6 0.0 7.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Kp4 PF09044.5 EIW70581.1 - 0.0089 15.8 0.0 0.096 12.4 0.0 2.4 3 0 0 3 3 3 1 Kp4 FlaC_arch PF05377.6 EIW70582.1 - 0.0043 16.9 1.5 0.68 9.8 0.9 2.5 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) Snf7 PF03357.16 EIW70582.1 - 0.0065 15.8 0.4 0.0089 15.4 0.3 1.1 1 0 0 1 1 1 1 Snf7 Baculo_PEP_C PF04513.7 EIW70582.1 - 0.015 15.0 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF904 PF06005.7 EIW70582.1 - 0.019 15.2 0.3 0.033 14.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) YgaB PF14182.1 EIW70582.1 - 0.021 15.0 0.4 0.043 14.0 0.2 1.6 1 1 0 1 1 1 0 YgaB-like protein GCR PF02155.10 EIW70582.1 - 0.024 13.3 0.0 0.03 13.0 0.0 1.1 1 0 0 1 1 1 0 Glucocorticoid receptor S_layer_N PF05123.7 EIW70582.1 - 0.029 14.0 0.3 0.033 13.8 0.2 1.1 1 0 0 1 1 1 0 S-layer like family, N-terminal region Syntaxin-6_N PF09177.6 EIW70582.1 - 0.051 13.9 0.4 0.086 13.2 0.2 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Syntaxin PF00804.20 EIW70582.1 - 0.059 13.5 0.1 0.088 12.9 0.1 1.2 1 0 0 1 1 1 0 Syntaxin Malate_synthase PF01274.17 EIW70582.1 - 0.068 11.1 0.1 0.084 10.8 0.1 1.0 1 0 0 1 1 1 0 Malate synthase Ead_Ea22 PF13935.1 EIW70582.1 - 0.075 13.3 0.2 0.09 13.1 0.1 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein NEP PF10167.4 EIW70582.1 - 0.078 12.6 0.1 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein Filo_VP35 PF02097.10 EIW70582.1 - 0.12 11.5 0.5 0.24 10.5 0.1 1.6 2 0 0 2 2 2 0 Filoviridae VP35 COG2 PF06148.6 EIW70582.1 - 0.2 11.5 1.6 0.45 10.3 0.8 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1479 PF07350.7 EIW70583.1 - 1.6e-17 63.1 0.2 1.4e-07 30.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) G-alpha PF00503.15 EIW70584.1 - 5.1e-129 430.3 0.0 5.7e-129 430.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW70584.1 - 1.2e-15 57.1 0.6 1.9e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW70584.1 - 9.8e-05 21.5 0.1 0.34 10.0 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EIW70584.1 - 0.004 17.6 0.0 0.79 10.2 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EIW70584.1 - 0.036 13.5 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EIW70584.1 - 0.11 11.9 0.1 5.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1180 PF06679.7 EIW70584.1 - 2 8.2 5.4 3 7.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Fungal_trans PF04082.13 EIW70585.1 - 6.7e-15 54.6 0.2 1.1e-14 53.9 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EIW70585.1 - 8.9e-09 35.1 10.3 0.00024 21.2 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW70585.1 - 8.5e-07 28.8 6.7 0.00059 19.9 1.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW70585.1 - 0.0099 16.1 6.6 1.4 9.3 0.6 2.7 2 0 0 2 2 2 2 Zinc-finger double domain LIM PF00412.17 EIW70585.1 - 0.016 15.2 2.9 0.032 14.2 2.0 1.6 1 0 0 1 1 1 0 LIM domain DUF4551 PF15087.1 EIW70587.1 - 0.33 9.2 4.5 0.37 9.1 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Med15 PF09606.5 EIW70587.1 - 3.8 5.5 15.8 4.7 5.2 11.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF605 PF04652.11 EIW70587.1 - 4.7 6.5 14.1 5.6 6.2 9.8 1.1 1 0 0 1 1 1 0 Vta1 like CoA_trans PF01144.18 EIW70589.1 - 6.4e-103 342.5 2.7 4e-62 209.2 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EIW70589.1 - 0.079 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF2139 PF09910.4 EIW70590.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) DAO PF01266.19 EIW70593.1 - 6e-27 94.4 0.0 7.3e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_4 PF07993.7 EIW70594.1 - 0.0028 16.6 0.0 0.0096 14.8 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EIW70594.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EIW70594.1 - 0.021 14.2 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF500 PF04366.7 EIW70595.1 - 2.6e-36 123.8 0.1 5.1e-36 122.8 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) NAD_binding_2 PF03446.10 EIW70596.1 - 2.1e-23 82.9 0.0 3e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIW70596.1 - 0.00014 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EIW70596.1 - 0.00027 21.0 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EIW70596.1 - 0.0038 16.9 0.0 0.0079 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EIW70596.1 - 0.009 16.4 0.0 0.03 14.7 0.0 1.9 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EIW70596.1 - 0.0096 15.0 0.0 0.074 12.1 0.0 2.0 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MAM33 PF02330.11 EIW70597.1 - 2.6e-28 99.2 0.0 4.6e-28 98.3 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial glycoprotein UQ_con PF00179.21 EIW70598.1 - 3.9e-14 52.2 0.1 5e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Kelch_6 PF13964.1 EIW70598.1 - 0.11 12.7 0.2 0.31 11.2 0.1 1.9 1 0 0 1 1 1 0 Kelch motif Tet_JBP PF12851.2 EIW70601.1 - 1.9e-05 24.0 0.1 2.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Alpha_kinase PF02816.13 EIW70602.1 - 4.5e-07 29.7 0.1 3.9e-06 26.6 0.0 2.5 2 1 0 2 2 2 1 Alpha-kinase family CLTH PF10607.4 EIW70604.1 - 1.8e-34 118.5 0.0 3.9e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EIW70604.1 - 0.049 13.3 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Peptidase_C12 PF01088.16 EIW70605.1 - 1.1e-56 191.4 0.0 1.2e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CTD_bind PF04818.8 EIW70606.1 - 0.0027 17.8 0.0 0.0063 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-C2H2_4 PF13894.1 EIW70606.1 - 0.41 11.1 2.2 24 5.5 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW70606.1 - 1 9.3 2.4 15 5.6 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M20 PF01546.23 EIW70607.1 - 1.7e-25 89.6 0.0 2.5e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIW70607.1 - 7.5e-12 44.9 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Hydrolase_6 PF13344.1 EIW70608.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.16 EIW70609.1 - 2.4e-52 177.5 0.0 2.8e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ClpB_D2-small PF10431.4 EIW70609.1 - 0.13 12.1 0.0 0.43 10.5 0.0 1.8 1 1 1 2 2 2 0 C-terminal, D2-small domain, of ClpB protein AOX PF01786.12 EIW70611.1 - 2.9e-81 271.8 0.0 3.4e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.8 EIW70611.1 - 0.033 13.6 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 TFIIIC_delta PF12657.2 EIW70612.1 - 1.1e-15 57.7 0.1 7.8e-15 55.0 0.1 2.4 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EIW70612.1 - 4.9e-13 48.8 0.2 9.3e-13 47.9 0.2 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex RRN7 PF11781.3 EIW70612.1 - 0.3 10.6 6.2 0.15 11.6 0.8 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Ras PF00071.17 EIW70615.1 - 4e-58 195.3 0.1 4.7e-58 195.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW70615.1 - 2.7e-19 69.8 0.0 3.8e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW70615.1 - 1.5e-08 34.0 0.0 1.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW70615.1 - 3.6e-05 23.2 0.0 6.6e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW70615.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 EIW70615.1 - 0.14 11.5 0.3 1 8.7 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein FeoB_N PF02421.13 EIW70615.1 - 0.14 11.3 0.1 0.34 10.1 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Abhydrolase_5 PF12695.2 EIW70616.1 - 4.6e-14 52.4 0.2 9.6e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW70616.1 - 9.8e-11 41.2 0.0 1.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIW70616.1 - 5.6e-10 39.4 1.6 5.4e-09 36.2 1.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW70616.1 - 6.2e-07 29.1 0.4 0.00066 19.2 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EIW70616.1 - 4.2e-05 23.0 0.1 0.49 9.7 0.0 3.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.15 EIW70616.1 - 0.00083 18.8 0.1 0.0026 17.2 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Tannase PF07519.6 EIW70616.1 - 0.016 13.9 0.0 1.2 7.8 0.0 2.1 1 1 1 2 2 2 0 Tannase and feruloyl esterase Chlorophyllase PF07224.6 EIW70616.1 - 0.022 13.5 0.0 0.038 12.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Lactamase_B PF00753.22 EIW70616.1 - 0.028 14.0 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF2974 PF11187.3 EIW70616.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FSH1 PF03959.8 EIW70616.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1057 PF06342.7 EIW70616.1 - 0.28 9.9 0.0 0.44 9.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF2587 PF10759.4 EIW70617.1 - 0.049 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Sensor PF13796.1 EIW70617.1 - 7.4 6.1 9.8 1.1 8.8 3.1 2.2 2 0 0 2 2 2 0 Putative sensor zf-CCHC PF00098.18 EIW70618.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW70618.1 - 0.44 10.7 7.2 0.12 12.6 2.8 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Radial_spoke_3 PF06098.6 EIW70618.1 - 0.45 9.4 7.7 0.97 8.3 2.4 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 B56 PF01603.15 EIW70618.1 - 0.84 8.1 2.8 1.1 7.7 1.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) SET PF00856.23 EIW70619.1 - 0.01 16.1 0.0 1.3 9.3 0.0 2.3 1 1 0 1 1 1 0 SET domain Dabb PF07876.7 EIW70621.1 - 1.3e-14 54.3 0.0 1.5e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Pex2_Pex12 PF04757.9 EIW70622.1 - 2.6e-30 105.5 0.7 3.5e-30 105.1 0.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region VCBS PF13517.1 EIW70623.1 - 5.3e-28 97.1 12.4 1.2e-11 44.8 0.1 6.0 3 2 3 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EIW70623.1 - 1.7e-13 49.8 11.4 0.079 12.6 0.5 6.6 6 0 0 6 6 6 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 EIW70623.1 - 0.00049 19.5 0.8 0.18 11.2 0.0 4.1 4 1 1 5 5 5 1 Insecticide toxin TcdB middle/N-terminal region SARA PF11409.3 EIW70624.1 - 0.038 13.9 0.1 0.098 12.5 0.1 1.7 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) Pex24p PF06398.6 EIW70625.1 - 4.2e-26 91.6 10.3 6.9e-18 64.5 5.0 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin DEAD PF00270.24 EIW70626.1 - 6.7e-38 129.8 0.0 1.2e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW70626.1 - 1.3e-23 82.6 0.0 2.6e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW70626.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit G-alpha PF00503.15 EIW70628.1 - 1.1e-120 402.8 0.0 1.3e-120 402.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW70628.1 - 1.4e-15 56.9 0.1 5e-11 42.1 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW70628.1 - 0.00037 19.7 0.2 0.078 12.1 0.0 2.7 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EIW70628.1 - 0.038 13.5 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EIW70628.1 - 0.052 14.0 0.0 5.7 7.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 EIW70628.1 - 0.064 12.6 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW70628.1 - 0.064 13.2 0.0 1.7 8.5 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase RabGAP-TBC PF00566.13 EIW70629.1 - 2.2e-12 46.8 1.1 3.5e-09 36.4 0.3 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain zf-ZPR1 PF03367.8 EIW70630.1 - 2.8e-99 328.9 0.0 3.6e-50 169.2 0.0 3.2 3 0 0 3 3 3 3 ZPR1 zinc-finger domain HypA PF01155.14 EIW70630.1 - 0.00054 19.6 1.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EIW70630.1 - 0.003 16.7 0.4 0.011 14.8 0.0 2.2 2 1 0 2 2 2 1 zinc-ribbon domain UPF0547 PF10571.4 EIW70630.1 - 0.066 12.9 1.3 21 4.8 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Cys_rich_CPCC PF14206.1 EIW70630.1 - 0.19 11.3 2.5 11 5.7 0.0 2.8 3 0 0 3 3 3 0 Cysteine-rich CPCC DZR PF12773.2 EIW70630.1 - 1.3 8.9 7.0 0.44 10.4 0.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EIW70630.1 - 6.3 6.8 7.3 24 4.9 0.1 3.7 4 0 0 4 4 4 0 Zinc ribbon domain Peptidase_M28 PF04389.12 EIW70631.1 - 2e-27 96.1 0.0 3.1e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 DUF3844 PF12955.2 EIW70632.1 - 5.7e-21 74.5 11.3 2e-20 72.7 7.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 EIW70632.1 - 0.0024 18.0 9.2 0.0066 16.5 6.4 1.8 1 1 0 1 1 1 1 EGF-like domain Glyco_hydro_3_C PF01915.17 EIW70632.1 - 0.064 12.7 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain MULE PF10551.4 EIW70633.1 - 2e-13 50.3 1.4 9.7e-11 41.7 0.2 3.5 2 1 0 2 2 2 1 MULE transposase domain UCH PF00443.24 EIW70633.1 - 1e-08 34.6 0.0 2.8e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase rve PF00665.21 EIW70633.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain UCH_1 PF13423.1 EIW70633.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DDE_1 PF03184.14 EIW70637.1 - 1e-39 135.9 0.0 9.9e-39 132.7 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW70637.1 - 0.00052 19.7 0.0 0.0015 18.3 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CP12 PF02672.10 EIW70637.1 - 2.2 8.8 5.7 0.22 12.0 0.7 1.7 2 0 0 2 2 2 0 CP12 domain HAD_2 PF13419.1 EIW70638.1 - 1.2e-12 48.3 0.0 1.8e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW70638.1 - 1e-06 29.3 0.1 6.8e-06 26.6 0.0 1.9 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW70638.1 - 0.0036 16.9 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EIW70638.1 - 0.04 14.0 0.0 0.062 13.4 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EIW70638.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ox_reductase_C PF08635.5 EIW70639.1 - 1.1e-43 148.1 0.0 1.5e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EIW70639.1 - 1.6e-12 47.9 0.0 3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIW70639.1 - 0.0025 17.6 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Flavoprotein PF02441.14 EIW70641.1 - 2e-41 140.7 0.0 3.1e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein AAA_2 PF07724.9 EIW70642.1 - 8.3e-49 165.7 0.0 8.5e-46 155.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EIW70642.1 - 1.6e-25 88.8 2.8 1.1e-24 86.1 0.1 3.3 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EIW70642.1 - 5.9e-25 87.9 0.1 7e-13 48.9 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW70642.1 - 2.1e-16 59.9 0.1 2.8e-10 40.0 0.0 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIW70642.1 - 3.8e-14 52.9 0.2 2.8e-05 24.2 0.0 3.7 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EIW70642.1 - 3.4e-12 46.7 8.3 1.3e-05 25.2 0.0 5.2 3 2 1 6 6 5 2 AAA ATPase domain Sigma54_activat PF00158.21 EIW70642.1 - 3.4e-10 39.6 0.0 6.3e-08 32.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Clp_N PF02861.15 EIW70642.1 - 3.5e-08 33.2 3.6 1.6e-05 24.7 0.2 3.3 2 1 0 2 2 2 2 Clp amino terminal domain IstB_IS21 PF01695.12 EIW70642.1 - 1.3e-07 31.2 0.0 0.016 14.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EIW70642.1 - 1.5e-06 27.8 0.1 0.057 13.1 0.1 2.9 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 EIW70642.1 - 6.6e-06 25.3 1.7 0.0004 19.5 0.0 3.8 4 0 0 4 4 4 1 Zeta toxin AAA_14 PF13173.1 EIW70642.1 - 9.5e-06 25.5 0.0 0.026 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EIW70642.1 - 1.5e-05 24.7 0.2 0.23 11.0 0.0 3.3 2 1 0 2 2 2 2 NACHT domain Mg_chelatase PF01078.16 EIW70642.1 - 2.1e-05 23.7 0.0 0.0025 17.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EIW70642.1 - 4.5e-05 23.1 0.0 0.0037 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIW70642.1 - 6.4e-05 22.9 0.1 1 9.2 0.0 4.0 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.17 EIW70642.1 - 0.00011 22.3 0.1 0.38 10.9 0.0 2.9 3 0 0 3 3 2 1 RNA helicase DUF2075 PF09848.4 EIW70642.1 - 0.00016 20.7 0.0 0.078 11.9 0.0 2.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EIW70642.1 - 0.00019 22.2 11.7 0.13 13.0 0.0 4.3 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EIW70642.1 - 0.0003 20.6 1.5 0.052 13.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EIW70642.1 - 0.00042 20.6 0.5 0.088 13.1 0.0 3.4 3 0 0 3 3 3 1 ABC transporter ResIII PF04851.10 EIW70642.1 - 0.00043 20.1 0.0 0.74 9.6 0.0 3.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EIW70642.1 - 0.00083 18.8 1.7 0.47 9.8 0.0 4.2 3 1 1 4 4 4 1 AAA-like domain AAA_18 PF13238.1 EIW70642.1 - 0.0018 18.5 8.8 0.072 13.4 0.0 3.7 4 0 0 4 4 2 2 AAA domain AAA_29 PF13555.1 EIW70642.1 - 0.0028 17.1 0.1 1.3 8.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 EIW70642.1 - 0.0036 16.2 0.0 0.054 12.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_3 PF07726.6 EIW70642.1 - 0.0038 16.8 0.2 6.6 6.3 0.1 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EIW70642.1 - 0.0043 16.2 0.1 2.3 7.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EIW70642.1 - 0.0045 16.7 0.0 1.9 8.1 0.0 3.8 3 0 0 3 3 3 1 NTPase Laminin_II PF06009.7 EIW70642.1 - 0.0045 16.7 0.8 0.014 15.1 0.6 1.9 1 0 0 1 1 1 1 Laminin Domain II UPF0079 PF02367.12 EIW70642.1 - 0.0055 16.3 0.0 2.7 7.6 0.0 2.8 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EIW70642.1 - 0.0056 16.3 0.0 2.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 EIW70642.1 - 0.006 15.8 0.0 0.091 11.9 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein RuvB_N PF05496.7 EIW70642.1 - 0.0092 15.0 3.6 0.27 10.2 0.0 3.5 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EIW70642.1 - 0.013 14.4 0.1 4.9 5.9 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF815) Torsin PF06309.6 EIW70642.1 - 0.014 15.2 0.0 0.079 12.8 0.0 2.2 2 0 0 2 2 1 0 Torsin AAA_25 PF13481.1 EIW70642.1 - 0.015 14.7 5.7 0.59 9.5 0.2 3.6 3 1 0 3 3 2 0 AAA domain Phage_GP20 PF06810.6 EIW70642.1 - 0.018 14.5 3.1 0.064 12.6 2.1 1.9 1 0 0 1 1 1 0 Phage minor structural protein GP20 Arch_ATPase PF01637.13 EIW70642.1 - 0.018 14.7 11.7 0.22 11.1 0.1 4.6 3 2 1 4 4 3 0 Archaeal ATPase PilJ PF13675.1 EIW70642.1 - 0.025 14.8 8.1 1 9.6 2.5 3.9 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sigma54_activ_2 PF14532.1 EIW70642.1 - 0.038 14.0 0.0 2.8 7.9 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain Miro PF08477.8 EIW70642.1 - 0.041 14.3 0.0 2.7 8.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein SRP54 PF00448.17 EIW70642.1 - 0.062 12.7 0.2 4.5 6.6 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain GSP_synth PF03738.9 EIW70642.1 - 0.098 12.9 0.0 1.1 9.5 0.0 2.7 3 0 0 3 3 1 0 Glutathionylspermidine synthase preATP-grasp NB-ARC PF00931.17 EIW70642.1 - 0.11 11.2 0.3 21 3.8 0.0 3.1 2 1 1 3 3 3 0 NB-ARC domain AAA_21 PF13304.1 EIW70642.1 - 0.11 12.3 0.0 15 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain KaiC PF06745.8 EIW70642.1 - 0.17 10.9 7.6 5.6 6.0 0.1 4.4 4 1 1 5 5 4 0 KaiC AAA_13 PF13166.1 EIW70642.1 - 0.45 8.9 6.5 1.3 7.4 4.4 1.7 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.4 EIW70642.1 - 0.81 7.8 7.8 1.3 7.1 5.4 1.3 1 0 0 1 1 1 0 Transmembrane protein AAA_23 PF13476.1 EIW70642.1 - 1.3 9.3 0.0 1.3 9.3 0.0 4.0 3 1 0 3 3 2 0 AAA domain TPR_MLP1_2 PF07926.7 EIW70642.1 - 3.1 7.5 14.6 10 5.8 1.9 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ADH_N PF08240.7 EIW70643.1 - 8e-25 86.7 1.5 1.8e-24 85.5 1.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW70643.1 - 3.9e-17 62.0 0.0 7.4e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW70643.1 - 0.0004 21.2 0.0 0.0011 19.8 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TRAP_alpha PF03896.11 EIW70644.1 - 1.3e-09 37.4 0.0 1.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit GAS PF13851.1 EIW70646.1 - 0.13 11.4 11.5 0.22 10.6 7.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Lge1 PF11488.3 EIW70646.1 - 1.1 9.4 12.2 3.8 7.7 5.7 3.0 1 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 Vac_Fusion PF02346.11 EIW70646.1 - 2.9 7.3 5.4 0.61 9.5 0.7 2.1 2 0 0 2 2 2 0 Chordopoxvirus fusion protein MULE PF10551.4 EIW70647.1 - 3.2e-05 24.0 0.0 7.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Cyclin_N PF00134.18 EIW70648.1 - 4.1e-08 32.8 0.0 6.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIW70648.1 - 7e-08 33.0 0.0 1.4e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin Metallophos_2 PF12850.2 EIW70649.1 - 9.3e-19 67.7 0.0 1.2e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIW70649.1 - 0.11 11.8 0.1 1.2 8.4 0.0 2.1 1 1 0 2 2 2 0 Calcineurin-like phosphoesterase zf-DHHC PF01529.15 EIW70650.1 - 1e-30 106.3 0.0 2.4e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Peptidase_M28 PF04389.12 EIW70651.1 - 9e-16 58.1 0.0 2.2e-15 56.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EIW70651.1 - 2e-13 50.0 0.0 1.2e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EIW70651.1 - 3.3e-06 26.7 0.1 6e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 PA domain PNP_UDP_1 PF01048.15 EIW70652.1 - 1.6e-34 118.8 0.0 1.9e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Alginate_lyase PF05426.7 EIW70653.1 - 3.8e-51 174.0 0.3 7.1e-51 173.1 0.2 1.4 1 0 0 1 1 1 1 Alginate lyase MOZART1 PF12554.3 EIW70654.1 - 2.1e-19 68.6 0.1 2.4e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated UCH PF00443.24 EIW70655.1 - 4.3e-29 101.4 0.0 6.7e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW70655.1 - 2.5e-09 36.9 0.0 1.3e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1077 PF06417.7 EIW70656.1 - 2.9e-44 149.4 0.1 3.4e-44 149.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) IMS PF00817.15 EIW70659.1 - 1.8e-38 131.6 0.2 3.9e-38 130.5 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EIW70659.1 - 1.3e-17 63.9 0.0 4.8e-17 62.0 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EIW70659.1 - 1.2e-10 41.2 0.3 3.4e-05 23.7 0.0 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EIW70659.1 - 1.9e-05 24.7 0.0 5.8e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EIW70659.1 - 0.0021 18.0 0.0 0.0057 16.6 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Kinesin PF00225.18 EIW70660.1 - 7e-103 343.8 0.0 9.6e-103 343.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain zf-C2H2 PF00096.21 EIW70661.1 - 2.6e-07 30.5 15.7 0.00091 19.4 0.2 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW70661.1 - 3.8e-07 30.0 14.9 0.00014 21.9 0.7 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW70661.1 - 8.9e-07 28.8 15.9 0.0041 17.3 0.4 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW70661.1 - 3.3 7.7 9.7 0.45 10.4 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_M20 PF01546.23 EIW70662.1 - 1.6e-35 122.3 0.0 2.5e-35 121.6 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIW70662.1 - 6.5e-09 35.5 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EIW70662.1 - 0.052 13.2 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Y_phosphatase2 PF03162.8 EIW70663.1 - 3.4e-29 101.3 0.0 7.3e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family ADH_zinc_N PF00107.21 EIW70664.1 - 2.5e-05 23.8 0.0 4.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NST1 PF13945.1 EIW70664.1 - 0.29 11.1 2.0 0.64 10.0 1.4 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator zf-C3HC4_3 PF13920.1 EIW70667.1 - 2.8e-06 26.9 5.3 5.6e-06 25.9 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW70667.1 - 0.00022 20.8 6.1 0.00048 19.7 4.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW70667.1 - 0.0003 20.7 7.2 0.00087 19.2 5.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW70667.1 - 0.00032 20.2 7.0 0.00069 19.2 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 EIW70667.1 - 0.00099 19.0 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EIW70667.1 - 0.0011 18.7 6.7 0.0023 17.7 4.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 EIW70667.1 - 0.091 12.3 5.1 0.24 11.0 3.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EIW70667.1 - 0.25 10.9 4.1 0.091 12.3 0.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF4428 PF14471.1 EIW70667.1 - 0.46 10.2 2.2 87 2.9 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) DZR PF12773.2 EIW70667.1 - 2.1 8.2 5.6 11 5.9 3.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF2422 PF10337.4 EIW70668.1 - 3e-88 296.6 0.5 3e-88 296.6 0.4 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EIW70668.1 - 5e-38 130.9 0.0 8.5e-37 126.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EIW70668.1 - 6.9e-08 32.4 16.0 6.9e-08 32.4 11.1 3.4 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 EIW70668.1 - 0.047 12.3 0.0 0.086 11.4 0.0 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter SOBP PF15279.1 EIW70669.1 - 0.34 11.2 11.7 0.69 10.2 8.1 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Oxidored_FMN PF00724.15 EIW70671.1 - 3.6e-65 220.2 0.0 7.4e-65 219.1 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Synaptobrevin PF00957.16 EIW70673.1 - 1.2e-30 104.9 0.0 1.7e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EIW70673.1 - 7.8e-24 83.0 0.0 1.4e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain tRNA-synt_1g PF09334.6 EIW70673.1 - 0.11 11.1 0.1 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) JAB PF01398.16 EIW70674.1 - 2.2e-35 120.8 0.2 4.3e-35 119.9 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EIW70674.1 - 5.3e-28 97.4 1.7 7.1e-28 96.9 0.6 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EIW70674.1 - 1.7e-07 30.7 0.0 3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain SPT2 PF08243.6 EIW70675.1 - 2.3e-15 56.9 12.4 2.3e-15 56.9 8.6 3.0 3 0 0 3 3 3 1 SPT2 chromatin protein Lactamase_B_2 PF12706.2 EIW70676.1 - 9.8e-27 93.7 0.1 2e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIW70676.1 - 0.0085 15.8 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Seipin PF06775.9 EIW70677.1 - 4.9e-06 26.2 0.0 9.3e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF1748 PF08520.5 EIW70678.1 - 2.1e-17 62.5 0.0 2.3e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DUF2269 PF10027.4 EIW70684.1 - 0.67 9.7 3.3 1.4 8.7 2.2 1.7 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Mucin PF01456.12 EIW70688.1 - 7.8 6.2 10.6 7.5 6.3 0.2 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein PepSY_2 PF13670.1 EIW70689.1 - 0.14 12.0 1.3 0.28 11.0 0.9 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain zf-CCHC PF00098.18 EIW70690.1 - 0.0017 18.2 1.5 0.003 17.4 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle PEX11 PF05648.9 EIW70692.1 - 3.7e-47 160.4 4.4 4.5e-47 160.1 3.1 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF155 PF02582.9 EIW70693.1 - 8.2e-42 143.0 0.0 1.2e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Aconitase PF00330.15 EIW70694.1 - 1.7e-175 583.9 0.0 2e-175 583.7 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIW70694.1 - 1.2e-40 138.6 0.0 2.1e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Dus PF01207.12 EIW70695.1 - 3.2e-48 164.1 0.0 6.5e-48 163.1 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Prolactin_RP PF15172.1 EIW70695.1 - 0.058 12.6 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Prolactin-releasing peptide DnaJ PF00226.26 EIW70696.1 - 8e-07 28.7 0.0 9.3e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EIW70696.1 - 0.011 15.4 0.0 0.012 15.4 0.0 1.0 1 0 0 1 1 1 0 Pam16 Ribosomal_L7Ae PF01248.21 EIW70697.1 - 7.2e-25 86.3 0.1 8.3e-25 86.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family APP_Cu_bd PF12924.2 EIW70697.1 - 0.077 13.5 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD Methyltransf_16 PF10294.4 EIW70698.1 - 2.7e-10 39.9 0.0 4.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EIW70698.1 - 1.8e-05 24.2 0.0 2.6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EIW70698.1 - 4.7e-05 23.9 0.0 0.00011 22.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EIW70698.1 - 0.00076 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 EIW70698.1 - 0.0066 15.6 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EIW70698.1 - 0.0067 15.4 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EIW70698.1 - 0.0095 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW70698.1 - 0.02 15.3 0.0 0.052 14.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EIW70698.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIW70698.1 - 0.086 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Saccharop_dh PF03435.13 EIW70700.1 - 5.7e-75 252.6 0.0 7.9e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_N PF05222.10 EIW70700.1 - 9.8e-18 64.4 0.0 1.7e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EIW70700.1 - 1.4e-15 57.2 0.0 6.6e-14 51.8 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EIW70700.1 - 5.9 7.0 5.4 0.85 9.7 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase PIN_4 PF13638.1 EIW70702.1 - 1.6e-15 57.4 0.6 4.6e-14 52.6 0.4 2.0 1 1 0 1 1 1 1 PIN domain TPP_enzyme_N PF02776.13 EIW70703.1 - 2e-55 186.9 0.0 5.7e-55 185.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EIW70703.1 - 6.8e-47 158.8 0.4 3e-45 153.5 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIW70703.1 - 8.3e-38 129.2 0.4 2.1e-37 127.9 0.3 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF3518 PF12031.3 EIW70704.1 - 0.00011 21.1 0.6 0.093 11.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3518) DUF70 PF01901.11 EIW70704.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF70 ARID PF01388.16 EIW70704.1 - 0.088 12.6 0.0 0.24 11.2 0.0 1.7 1 1 0 1 1 1 0 ARID/BRIGHT DNA binding domain EAP30 PF04157.11 EIW70705.1 - 4.9e-25 87.9 0.0 6.8e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family DZR PF12773.2 EIW70705.1 - 0.00091 19.0 4.7 0.011 15.5 0.4 2.3 2 0 0 2 2 2 1 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 EIW70705.1 - 0.03 13.8 5.0 2.3 7.8 0.0 2.7 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EIW70705.1 - 0.073 12.1 7.7 1.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.1 EIW70705.1 - 2.1 7.6 11.0 2.6 7.3 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.1 EIW70705.1 - 3.9 7.4 4.5 3.2 7.6 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 GCC2_GCC3 PF07699.8 EIW70705.1 - 8.7 6.0 7.9 1.2 8.7 1.2 2.3 2 0 0 2 2 2 0 GCC2 and GCC3 G-patch PF01585.18 EIW70706.1 - 0.00046 19.9 0.0 0.00097 18.8 0.0 1.5 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EIW70706.1 - 0.0032 17.2 0.0 0.012 15.4 0.0 2.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtt102p PF09510.5 EIW70707.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein Spc97_Spc98 PF04130.8 EIW70708.1 - 1.1e-135 453.0 0.0 1.3e-135 452.8 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF2587 PF10759.4 EIW70710.1 - 0.049 13.0 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PepSY_2 PF13670.1 EIW70710.1 - 0.11 12.4 0.7 0.21 11.5 0.5 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain SR-25 PF10500.4 EIW70710.1 - 3.1 7.2 27.6 0.048 13.1 8.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GPI-anchored PF10342.4 EIW70712.1 - 0.016 15.6 0.6 0.024 15.1 0.4 1.3 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Casein_kappa PF00997.13 EIW70712.1 - 0.079 12.6 1.2 2 8.0 0.1 2.0 1 1 1 2 2 2 0 Kappa casein tRNA-synt_1 PF00133.17 EIW70713.1 - 2.7e-216 719.2 0.0 5.8e-216 718.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIW70713.1 - 6.3e-26 90.9 0.0 1.9e-24 86.1 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIW70713.1 - 3.9e-18 65.2 0.7 2.6e-06 26.3 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EIW70713.1 - 0.0063 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain zf-CCHC PF00098.18 EIW70714.1 - 2.4e-12 46.1 34.8 0.00012 21.8 0.6 6.1 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.1 EIW70714.1 - 0.53 10.0 22.2 7.8 6.3 0.7 4.9 3 1 1 4 4 4 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIW70714.1 - 2.2 7.9 29.0 2.3 7.9 0.9 4.9 4 1 1 5 5 5 0 Zinc knuckle DUF2072 PF09845.4 EIW70714.1 - 2.9 7.8 6.3 0.25 11.2 0.4 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) zf-CCHC_2 PF13696.1 EIW70714.1 - 3.2 7.3 15.3 0.83 9.2 0.4 3.6 3 0 0 3 3 3 0 Zinc knuckle RasGEF PF00617.14 EIW70717.1 - 5.9e-35 120.6 0.0 4.9e-34 117.7 0.0 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EIW70717.1 - 1.5e-08 34.6 0.2 3.7e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EIW70717.1 - 8.6e-08 32.6 0.0 1.8e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EIW70717.1 - 8.6e-06 25.2 0.0 9.3e-05 21.8 0.0 2.3 1 1 0 1 1 1 1 Ras family AAA_30 PF13604.1 EIW70717.1 - 0.0095 15.5 0.1 0.064 12.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EIW70717.1 - 0.095 12.3 0.0 0.44 10.1 0.0 2.1 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.1 EIW70717.1 - 0.1 12.7 0.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIW70717.1 - 0.15 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Aha1_N PF09229.6 EIW70718.1 - 1.8e-27 95.8 0.0 2.7e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EIW70718.1 - 3.8e-13 49.6 0.0 7.2e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EIW70718.1 - 0.00029 21.0 0.1 0.00083 19.5 0.0 1.8 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport ANF_receptor PF01094.23 EIW70718.1 - 0.094 11.4 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Spc97_Spc98 PF04130.8 EIW70720.1 - 8.9e-57 192.6 0.0 1.6e-56 191.7 0.0 1.3 1 1 0 1 1 1 1 Spc97 / Spc98 family Kinesin PF00225.18 EIW70721.1 - 1.1e-91 307.0 1.5 7.2e-49 166.2 0.0 3.3 3 1 1 4 4 4 2 Kinesin motor domain S1-P1_nuclease PF02265.11 EIW70722.1 - 1.3e-51 175.6 0.0 7.7e-45 153.4 0.0 2.0 2 0 0 2 2 2 2 S1/P1 Nuclease NUDIX PF00293.23 EIW70723.1 - 7.2e-25 87.1 0.0 1e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain YL1_C PF08265.6 EIW70725.1 - 8.8e-14 50.7 0.1 2.5e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Daxx PF03344.10 EIW70725.1 - 4.3 5.7 6.6 5.6 5.3 4.6 1.1 1 0 0 1 1 1 0 Daxx Family MPC PF03650.8 EIW70726.1 - 1.3e-32 112.2 0.1 1.6e-32 111.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) bZIP_1 PF00170.16 EIW70727.1 - 1.2e-08 34.8 11.9 1.2e-08 34.8 8.2 2.0 2 0 0 2 2 2 1 bZIP transcription factor FliD_N PF02465.13 EIW70727.1 - 0.093 13.1 8.8 0.14 12.5 1.6 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF972 PF06156.8 EIW70727.1 - 0.41 11.0 3.7 0.29 11.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 EIW70727.1 - 1.2 9.4 20.1 0.071 13.4 5.5 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF812 PF05667.6 EIW70727.1 - 1.7 7.0 11.8 0.27 9.6 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) SNF2_N PF00176.18 EIW70729.1 - 1.6e-62 211.0 0.0 2.2e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EIW70729.1 - 3.5e-22 78.3 0.0 8.1e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EIW70729.1 - 1.1e-14 54.0 0.0 2.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW70729.1 - 1.5e-09 37.9 0.0 6.3e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EIW70729.1 - 0.049 13.2 9.2 1.8 8.2 2.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW70729.1 - 0.56 9.9 8.6 0.73 9.5 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW70729.1 - 0.94 9.3 8.8 5.5 6.9 6.1 2.1 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EIW70729.1 - 1.2 9.1 10.3 4.8 7.3 0.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2305 PF10230.4 EIW70730.1 - 2.6e-42 145.0 0.0 4.6e-41 140.9 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 EIW70730.1 - 0.00037 19.9 0.0 0.00054 19.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EIW70730.1 - 0.0014 18.4 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW70730.1 - 0.0027 17.6 0.5 0.0031 17.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 EIW70730.1 - 0.11 11.2 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family OpcA_G6PD_assem PF10128.4 EIW70731.1 - 0.0029 16.5 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase subunit VPEP PF07589.6 EIW70732.1 - 3.8 7.5 12.8 1.3 9.0 1.2 2.8 3 0 0 3 3 3 0 PEP-CTERM motif V_ATPase_I PF01496.14 EIW70733.1 - 8.3 4.1 5.2 12 3.6 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NAD_binding_10 PF13460.1 EIW70734.1 - 6.2e-15 55.6 0.0 8.7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW70734.1 - 8.7e-12 44.3 0.0 8.1e-05 21.4 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIW70734.1 - 3.1e-10 39.8 0.0 1.7e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW70734.1 - 2.9e-05 23.4 0.0 3.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EIW70734.1 - 8.1e-05 21.6 0.0 0.0017 17.3 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 EIW70734.1 - 9.7e-05 22.3 0.1 0.00021 21.2 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EIW70734.1 - 0.0016 17.3 0.0 0.021 13.7 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EIW70734.1 - 0.0023 16.8 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PAC2 PF09754.4 EIW70734.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 PAC2 family Glyco_hydro_cc PF11790.3 EIW70737.1 - 2.2e-45 154.9 0.7 3.1e-45 154.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core CytochromB561_N PF09786.4 EIW70737.1 - 3.8 5.8 10.7 5.2 5.3 7.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DSPc PF00782.15 EIW70741.1 - 1.8e-20 72.9 0.0 2.2e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RRM_1 PF00076.17 EIW70743.1 - 3.3e-17 61.8 0.0 4.2e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW70743.1 - 4.8e-16 58.5 0.0 6.9e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW70743.1 - 2e-13 49.9 0.0 2.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WBS_methylT PF12589.3 EIW70744.1 - 8.7e-16 58.1 12.5 1.5e-15 57.4 8.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EIW70744.1 - 2.2e-10 40.9 0.0 3.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW70744.1 - 4.9e-08 32.8 0.0 7.8e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW70744.1 - 6.3e-06 26.5 0.0 1.6e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW70744.1 - 9.3e-06 25.9 0.0 2.4e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW70744.1 - 4.5e-05 23.9 0.0 6.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW70744.1 - 9.7e-05 22.0 0.0 0.00013 21.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW70744.1 - 0.014 15.3 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.8 EIW70744.1 - 0.078 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Sec15 PF04091.7 EIW70745.1 - 1.2e-91 307.2 1.3 1.3e-91 307.1 0.2 1.5 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 EIW70745.1 - 0.00011 22.0 0.0 0.0009 19.0 0.0 2.5 3 1 1 4 4 4 1 Exocyst complex component Sec5 COG2 PF06148.6 EIW70745.1 - 0.0095 15.8 3.0 0.031 14.1 0.2 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.9 EIW70745.1 - 0.01 15.4 1.0 0.022 14.4 0.0 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Vps51 PF08700.6 EIW70745.1 - 0.019 14.8 1.2 0.058 13.2 0.0 2.5 3 0 0 3 3 3 0 Vps51/Vps67 COG5 PF10392.4 EIW70745.1 - 0.031 14.2 2.5 0.034 14.1 0.1 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 ATP_synt_H PF05493.8 EIW70746.1 - 8.7e-25 86.5 1.0 9.6e-25 86.4 0.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.1 EIW70746.1 - 0.011 15.6 0.3 0.016 15.1 0.2 1.4 1 1 0 1 1 1 0 Haemopoietic lineage transmembrane helix Cation_ATPase_C PF00689.16 EIW70746.1 - 0.084 12.3 0.2 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Intg_mem_TP0381 PF09529.5 EIW70746.1 - 0.19 10.9 2.6 0.22 10.7 1.8 1.0 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) DUF4117 PF13491.1 EIW70746.1 - 0.31 10.4 2.1 0.33 10.3 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) DUF4131 PF13567.1 EIW70746.1 - 0.56 9.5 2.9 0.59 9.5 2.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Amastin PF07344.6 EIW70747.1 - 0.026 14.1 1.2 0.57 9.7 0.2 2.7 2 1 0 2 2 2 0 Amastin surface glycoprotein Methyltransf_6 PF03737.10 EIW70750.1 - 6.2e-24 84.6 0.0 7.4e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Skp1_POZ PF03931.10 EIW70751.1 - 7.9e-10 38.6 0.1 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Sas10_Utp3 PF04000.10 EIW70752.1 - 3.4e-18 65.6 0.0 6.3e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Hid1 PF12722.2 EIW70753.1 - 1.2 6.7 3.3 1.5 6.3 2.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EI24 PF07264.6 EIW70754.1 - 2.1e-15 56.7 14.2 3.5e-15 56.0 9.8 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Adaptin_N PF01602.15 EIW70755.1 - 1.1e-141 472.7 7.4 1.3e-141 472.5 5.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EIW70755.1 - 3e-21 75.8 1.1 6.9e-21 74.7 0.7 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EIW70755.1 - 1.3e-05 25.3 1.1 0.42 10.9 0.0 4.9 4 2 1 5 5 4 2 HEAT repeats HEAT PF02985.17 EIW70755.1 - 0.0015 18.4 1.0 15 5.9 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EIW70755.1 - 0.0015 18.3 3.4 0.037 13.8 0.5 3.5 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 EIW70755.1 - 0.018 14.6 1.0 0.12 11.8 0.2 2.6 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) Exo_endo_phos PF03372.18 EIW70756.1 - 4.1e-16 59.6 0.3 6.6e-16 58.9 0.0 1.4 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Mito_fiss_reg PF05308.6 EIW70756.1 - 0.91 8.8 5.2 1.5 8.1 3.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Zn_clus PF00172.13 EIW70758.1 - 0.14 12.1 3.7 0.29 11.0 2.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.22 EIW70759.1 - 2.6e-18 65.0 2.3 2.6e-18 65.0 1.6 1.8 2 0 0 2 2 2 1 GATA zinc finger DUF1752 PF08550.5 EIW70759.1 - 4.9e-11 42.0 1.8 1.1e-10 40.9 1.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) BTD PF09270.5 EIW70760.1 - 8.3e-26 90.6 0.0 1.5e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 EIW70760.1 - 9.9e-11 42.2 0.0 3.8e-09 37.1 0.0 2.8 2 0 0 2 2 2 1 LAG1, DNA binding Rad60-SLD PF11976.3 EIW70761.1 - 6.9e-13 48.0 0.0 4.1e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like AAA PF00004.24 EIW70761.1 - 0.001 19.2 1.2 0.018 15.2 0.8 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW70761.1 - 0.0019 18.9 0.0 0.0063 17.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIW70761.1 - 0.0041 16.6 0.0 0.0097 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.10 EIW70761.1 - 0.0043 15.8 0.0 0.0097 14.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EIW70761.1 - 0.009 16.0 0.0 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 EIW70761.1 - 0.076 11.8 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 EIW70761.1 - 0.08 12.6 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EIW70761.1 - 0.084 12.6 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 EIW70761.1 - 0.088 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EIW70761.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain FF PF01846.14 EIW70763.1 - 5.2e-37 125.5 29.1 6.1e-10 38.9 0.0 7.1 7 0 0 7 7 7 5 FF domain WW PF00397.21 EIW70763.1 - 2.3e-07 30.5 10.4 2.8e-05 23.8 0.7 2.9 2 0 0 2 2 2 2 WW domain Fe-ADH PF00465.14 EIW70764.1 - 2.5e-79 266.5 0.0 3.4e-79 266.1 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EIW70764.1 - 4.5e-08 32.6 0.0 2.2e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase ESSS PF10183.4 EIW70767.1 - 9.2e-25 87.0 0.1 1.1e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HupE_UreJ_2 PF13795.1 EIW70767.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 HupE / UreJ protein PgaD PF13994.1 EIW70768.1 - 0.014 14.8 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 PgaD-like protein MLANA PF14991.1 EIW70768.1 - 0.048 13.6 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A Cactin_mid PF10312.4 EIW70769.1 - 4.5e-61 205.4 0.7 1.4e-60 203.8 0.5 1.9 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EIW70769.1 - 3.3e-53 178.5 2.9 5.8e-53 177.7 2.0 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein FAD_binding_6 PF00970.19 EIW70770.1 - 1.7e-11 44.0 0.0 5.9e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EIW70770.1 - 0.00047 20.0 0.0 0.00089 19.1 0.0 1.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EIW70770.1 - 0.074 13.6 0.0 0.46 11.0 0.0 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain LGFP PF08310.6 EIW70771.1 - 5.7e-06 25.8 0.6 0.89 9.2 0.0 3.4 3 0 0 3 3 3 3 LGFP repeat DUF4431 PF14485.1 EIW70771.1 - 0.023 14.2 0.1 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) PROCN PF08083.6 EIW70772.1 - 7.9e-218 722.8 5.8 1.2e-217 722.2 4.0 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EIW70772.1 - 1.8e-127 423.3 0.8 3e-127 422.6 0.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EIW70772.1 - 2.3e-88 293.5 0.4 4.7e-88 292.5 0.2 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EIW70772.1 - 2.1e-80 267.7 2.1 5e-80 266.4 1.4 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EIW70772.1 - 5.1e-67 223.6 0.0 9.4e-67 222.7 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EIW70772.1 - 1.6e-44 149.6 0.1 3.8e-44 148.4 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EIW70772.1 - 1.9e-37 127.7 0.0 6e-37 126.1 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 EIW70772.1 - 1.7e-06 27.7 0.0 4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Lactococcin_972 PF09683.5 EIW70772.1 - 0.04 14.2 0.7 0.13 12.6 0.5 1.9 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) SurE PF01975.12 EIW70773.1 - 5.6e-37 126.9 0.0 9.2e-36 122.9 0.0 2.0 1 1 0 1 1 1 1 Survival protein SurE PQ-loop PF04193.9 EIW70774.1 - 4.8e-18 64.4 13.6 3.3e-09 36.1 1.6 2.6 2 0 0 2 2 2 2 PQ loop repeat Ferric_reduct PF01794.14 EIW70775.1 - 2.4e-16 59.9 5.5 2.4e-16 59.9 3.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIW70775.1 - 1.6e-11 43.9 0.0 2.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EIW70775.1 - 3.1e-11 43.4 0.0 2.7e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EIW70775.1 - 0.18 12.3 0.1 2.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2306 PF10067.4 EIW70775.1 - 2.4 8.3 9.0 0.48 10.5 0.6 2.9 3 1 0 3 3 3 0 Predicted membrane protein (DUF2306) UCH PF00443.24 EIW70776.1 - 1.4e-41 142.3 0.0 4.8e-41 140.6 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EIW70776.1 - 2.3e-18 65.3 0.3 3.4e-12 45.5 0.0 3.5 3 0 0 3 3 3 3 A repeated domain in UCH-protein UCH_1 PF13423.1 EIW70776.1 - 2.7e-11 43.4 0.0 0.00021 20.8 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3184 PF11380.3 EIW70776.1 - 0.078 10.9 0.0 0.15 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) zf-C2H2_4 PF13894.1 EIW70777.1 - 0.0085 16.3 7.0 0.41 11.0 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW70777.1 - 0.058 13.7 10.4 0.42 11.0 0.4 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type CHORD PF04968.7 EIW70777.1 - 0.53 10.5 4.1 3.5 7.9 0.1 2.7 3 0 0 3 3 3 0 CHORD CNH PF00780.17 EIW70778.1 - 2.9e-09 36.7 0.0 5.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 EIW70778.1 - 3.2e-07 30.5 0.0 3.7e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 TPR_4 PF07721.9 EIW70778.1 - 0.025 14.9 0.5 8.8 7.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.15 EIW70778.1 - 0.033 13.8 0.0 0.93 9.0 0.0 2.6 3 0 0 3 3 3 0 Region in Clathrin and VPS F-box PF00646.28 EIW70779.1 - 1.7e-07 30.7 0.0 4.3e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW70779.1 - 0.0029 17.2 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like Glutaredoxin2_C PF04399.8 EIW70780.1 - 0.0029 17.1 3.7 0.0062 16.1 2.6 1.5 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain Tweety PF04906.8 EIW70780.1 - 0.74 8.1 1.4 1.1 7.6 1.0 1.1 1 0 0 1 1 1 0 Tweety GAS PF13851.1 EIW70780.1 - 1.3 8.1 20.0 2.1 7.4 13.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EIW70780.1 - 2.1 7.8 8.0 5 6.6 5.5 1.6 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EIW70780.1 - 2.2 8.7 5.3 9.5 6.7 3.7 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.17 EIW70780.1 - 4.2 7.4 15.8 9.1 6.3 11.0 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HAD_2 PF13419.1 EIW70781.1 - 6.6e-07 29.7 0.1 2.6e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase NT5C PF06941.7 EIW70781.1 - 4.5e-06 26.2 0.9 0.00017 21.1 0.0 2.7 3 0 0 3 3 3 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) NIF PF03031.13 EIW70781.1 - 0.0029 17.3 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.2 EIW70781.1 - 0.0069 16.5 0.0 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase 5-nucleotidase PF06189.7 EIW70781.1 - 0.031 13.0 0.0 0.43 9.3 0.0 2.0 2 0 0 2 2 2 0 5'-nucleotidase TRP PF06011.7 EIW70782.1 - 8.1e-54 182.8 9.5 1.3e-53 182.1 6.6 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EIW70782.1 - 7.4e-06 26.0 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 ML-like domain GST_N_3 PF13417.1 EIW70783.1 - 4.6e-12 45.9 0.0 8.7e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW70783.1 - 5.2e-07 29.5 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW70783.1 - 5.8e-07 29.6 0.0 3.5e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain IRK PF01007.15 EIW70783.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Inward rectifier potassium channel SAICAR_synt PF01259.13 EIW70785.1 - 2.9e-81 272.2 0.0 4.4e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 SAICAR synthetase tRNA-synt_1b PF00579.20 EIW70785.1 - 2.9e-55 187.4 0.0 6e-55 186.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) B12D PF06522.6 EIW70786.1 - 5e-18 64.5 0.1 6.2e-18 64.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF1838 PF08894.6 EIW70786.1 - 0.031 13.4 0.9 0.039 13.1 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1838) Peptidase_S8 PF00082.17 EIW70787.1 - 2.1e-41 141.9 2.3 3.5e-41 141.2 1.6 1.4 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EIW70787.1 - 1.2e-13 50.6 0.0 4.7e-13 48.6 0.0 2.0 1 1 0 1 1 1 1 PA domain DUF1034 PF06280.7 EIW70787.1 - 1.2e-06 28.8 0.1 2.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Inhibitor_I9 PF05922.11 EIW70787.1 - 0.0014 19.1 0.1 0.0028 18.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sec16_C PF12931.2 EIW70788.1 - 5.3e-44 151.0 0.0 9.1e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EIW70788.1 - 1.9e-18 66.5 0.0 3.7e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region TEA PF01285.13 EIW70789.1 - 2e-06 27.2 0.8 1.3e-05 24.5 0.0 2.1 2 1 0 2 2 2 1 TEA/ATTS domain family NUC153 PF08159.7 EIW70790.1 - 3.4e-10 39.3 1.2 3.4e-10 39.3 0.8 3.5 3 0 0 3 3 3 1 NUC153 domain RRM_5 PF13893.1 EIW70790.1 - 0.024 14.4 0.1 0.055 13.3 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myc_N PF01056.13 EIW70790.1 - 2.9 6.9 20.6 0.049 12.7 2.5 3.0 2 0 0 2 2 2 0 Myc amino-terminal region FAD_binding_3 PF01494.14 EIW70791.1 - 1e-16 60.9 0.0 6.9e-15 54.9 0.0 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW70791.1 - 0.00024 21.0 0.0 0.0006 19.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EIW70791.1 - 0.00092 18.1 0.0 0.011 14.6 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EIW70791.1 - 0.016 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW70791.1 - 0.067 12.0 0.0 0.12 11.2 0.0 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EIW70791.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EIW70791.1 - 0.22 9.9 0.0 0.32 9.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein RRM_1 PF00076.17 EIW70793.1 - 5.9e-16 57.8 0.0 1.2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 EIW70793.1 - 2e-14 53.6 0.2 2e-14 53.6 0.1 2.5 1 1 1 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_6 PF14259.1 EIW70793.1 - 9.4e-13 47.9 0.0 1.9e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW70793.1 - 2.1e-06 27.5 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cmyb_C PF09316.5 EIW70793.1 - 0.13 11.8 0.9 0.26 10.9 0.6 1.6 1 1 0 1 1 1 0 C-myb, C-terminal Actin PF00022.14 EIW70794.1 - 2.5e-132 441.0 0.0 2.9e-132 440.8 0.0 1.0 1 0 0 1 1 1 1 Actin RRM_1 PF00076.17 EIW70795.1 - 8.3e-17 60.5 0.0 1.2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW70795.1 - 3.5e-14 52.5 0.0 5.2e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW70795.1 - 2.2e-06 27.4 0.0 3.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW70795.1 - 0.0024 17.5 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EIW70795.1 - 0.05 13.3 0.1 0.21 11.3 0.0 1.9 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ThiF PF00899.16 EIW70796.1 - 1.3e-50 170.7 0.1 2.3e-28 98.7 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EIW70796.1 - 3.6e-47 159.6 0.1 7.4e-47 158.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EIW70796.1 - 2.2e-38 129.6 0.4 4.1e-27 93.5 0.0 2.9 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EIW70796.1 - 6.9e-25 86.1 0.7 2.6e-20 71.5 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site 2-Hacid_dh_C PF02826.14 EIW70796.1 - 0.14 11.3 1.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ubie_methyltran PF01209.13 EIW70798.1 - 2.3e-74 249.4 0.0 3e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIW70798.1 - 2e-12 46.9 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW70798.1 - 1.9e-10 41.0 0.0 3.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW70798.1 - 5.3e-10 39.6 0.0 7.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW70798.1 - 8.4e-10 38.6 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW70798.1 - 1.3e-09 38.3 0.0 2.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW70798.1 - 4.4e-07 30.4 0.0 7.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW70798.1 - 0.00016 21.7 0.0 0.00073 19.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_5 PF01795.14 EIW70798.1 - 0.2 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family Use1 PF09753.4 EIW70799.1 - 0.034 13.5 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 PI31_Prot_N PF11566.3 EIW70801.1 - 1.9e-23 82.7 0.0 2.4e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EIW70801.1 - 1.6e-12 47.8 13.4 1.6e-12 47.8 9.3 3.6 2 1 0 2 2 2 1 PI31 proteasome regulator Tash_PEST PF07708.6 EIW70803.1 - 0.025 14.4 2.1 0.076 12.9 0.0 2.5 2 0 0 2 2 2 0 Tash protein PEST motif Sulfate_transp PF00916.15 EIW70806.1 - 1.5e-74 250.5 5.2 2.2e-74 249.9 3.6 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EIW70806.1 - 1.5e-32 111.0 1.4 7.3e-32 108.8 1.0 2.3 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EIW70806.1 - 3.4e-12 45.8 0.0 6.5e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EIW70806.1 - 0.074 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 STAS domain SecE PF00584.15 EIW70807.1 - 1.9e-11 43.3 0.1 2.1e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CbtB PF09489.5 EIW70807.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Chromo PF00385.19 EIW70809.1 - 2.1 8.1 4.8 3.4 7.4 0.5 2.2 1 1 1 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain PC4 PF02229.11 EIW70810.1 - 9.5e-21 72.7 0.2 1.6e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CobT PF06213.7 EIW70811.1 - 1.2 8.1 5.8 1.7 7.7 4.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 EIW70811.1 - 2.2 6.8 6.3 3.1 6.4 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 EIW70811.1 - 3.1 5.5 4.6 3.9 5.2 3.2 1.0 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 EIW70814.1 - 6.7e-70 235.1 0.0 8.6e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW70814.1 - 5e-32 110.9 0.0 2.5e-30 105.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW70814.1 - 0.00011 21.2 2.6 0.62 8.9 0.0 3.6 3 1 0 3 3 3 2 Kinase-like RIO1 PF01163.17 EIW70814.1 - 0.00021 20.7 0.5 0.0003 20.2 0.4 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIW70814.1 - 0.0078 15.9 1.0 0.31 10.7 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family 2OG-FeII_Oxy_2 PF13532.1 EIW70818.1 - 7.6e-13 48.7 0.1 7.9e-06 25.8 0.0 2.3 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily VirK PF06903.7 EIW70818.1 - 0.0052 16.5 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 VirK protein DUF4013 PF13197.1 EIW70819.1 - 0.017 14.4 5.8 0.02 14.2 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF1469 PF07332.6 EIW70819.1 - 0.086 12.5 0.3 0.1 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF4212 PF13937.1 EIW70819.1 - 0.61 10.1 4.6 0.78 9.7 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) Glycoprotein_B PF00606.13 EIW70819.1 - 0.79 7.6 4.9 0.93 7.4 3.4 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Myb_DNA-binding PF00249.26 EIW70820.1 - 1.5e-07 31.3 0.0 0.001 19.0 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW70820.1 - 0.0035 17.4 0.0 3.6 7.7 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain NUDIX_4 PF14815.1 EIW70821.1 - 7.5e-06 25.3 0.0 5.2e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.20 EIW70821.1 - 0.0014 18.8 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.4 EIW70821.1 - 0.015 15.4 6.4 0.042 14.0 4.5 1.9 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III HHH PF00633.18 EIW70821.1 - 0.018 14.7 0.1 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Dicty_REP PF05086.7 EIW70821.1 - 9.1 3.8 7.1 13 3.4 4.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Gly_transf_sug PF04488.10 EIW70822.1 - 2.4e-10 40.6 0.0 6.5e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIW70822.1 - 4.4e-05 22.7 0.0 7.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EIW70822.1 - 0.00017 20.2 0.2 0.00038 19.0 0.0 1.6 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain NAD_Gly3P_dh_C PF07479.9 EIW70823.1 - 5e-46 156.1 0.0 7.5e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EIW70823.1 - 5.3e-46 156.2 0.1 3.1e-45 153.7 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EIW70823.1 - 0.00041 20.7 0.7 0.0084 16.5 0.5 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CS PF04969.11 EIW70824.1 - 0.00063 20.2 0.0 0.0019 18.7 0.0 1.9 1 1 0 1 1 1 1 CS domain bZIP_1 PF00170.16 EIW70827.1 - 3.5e-05 23.6 10.0 3.5e-05 23.6 7.0 2.1 2 0 0 2 2 2 1 bZIP transcription factor Effector_1 PF04518.7 EIW70827.1 - 0.00056 19.0 0.7 0.00075 18.5 0.5 1.1 1 0 0 1 1 1 1 Effector from type III secretion system KaiC PF06745.8 EIW70827.1 - 0.0077 15.3 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 KaiC Prefoldin_3 PF13758.1 EIW70827.1 - 0.029 14.1 0.5 0.085 12.6 0.4 1.8 1 0 0 1 1 1 0 Prefoldin subunit DUF4200 PF13863.1 EIW70827.1 - 0.14 12.1 7.5 0.3 11.0 5.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4407 PF14362.1 EIW70827.1 - 0.14 11.0 5.0 0.19 10.6 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-met PF12874.2 EIW70831.1 - 0.042 14.0 0.3 9.3 6.6 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ribosomal_L41 PF05162.8 EIW70834.1 - 0.018 14.6 0.6 0.03 13.9 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein L41 PSI_PsaE PF02427.12 EIW70835.1 - 0.049 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE zf-CCHC PF00098.18 EIW70836.1 - 0.00012 21.8 1.8 0.00019 21.1 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIW70836.1 - 0.029 13.8 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIW70836.1 - 1.1 8.8 9.7 0.11 11.9 2.9 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger SR-25 PF10500.4 EIW70837.1 - 4.6 6.6 10.6 2.7 7.3 4.8 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DDE_1 PF03184.14 EIW70838.1 - 1.7e-33 115.5 0.0 3e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW70838.1 - 1.3e-05 24.9 0.0 3.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EIW70838.1 - 0.00015 21.5 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease PRP1_N PF06424.7 EIW70840.1 - 2.5e-44 150.8 3.5 2.5e-44 150.8 2.5 2.9 3 0 0 3 3 3 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EIW70840.1 - 4.4e-32 107.6 16.8 0.079 13.6 0.0 14.2 5 4 9 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.1 EIW70840.1 - 6e-20 71.3 9.0 2.8e-05 24.3 2.6 8.2 6 3 3 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EIW70840.1 - 1.6e-14 54.0 16.5 0.00022 21.7 0.0 7.1 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIW70840.1 - 7.1e-10 38.3 7.3 0.00067 19.2 0.1 7.3 6 1 1 7 7 7 1 TPR repeat TPR_2 PF07719.12 EIW70840.1 - 3e-09 36.0 4.2 0.076 12.9 0.0 7.5 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW70840.1 - 2.8e-08 33.6 12.0 0.16 12.4 0.0 8.3 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_21 PF09976.4 EIW70840.1 - 4.7e-07 29.8 5.4 4.7e-07 29.8 3.7 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat Suf PF05843.9 EIW70840.1 - 9.9e-07 28.7 0.0 4 7.0 0.0 4.9 3 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_17 PF13431.1 EIW70840.1 - 1.2e-06 28.2 0.1 1.4e+02 3.0 0.0 9.3 10 1 0 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW70840.1 - 1.1e-05 24.7 1.3 0.92 9.4 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW70840.1 - 0.00047 19.6 0.3 2.2 8.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW70840.1 - 0.04 14.0 1.4 0.2 11.8 0.4 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.3 EIW70840.1 - 0.17 10.6 14.4 0.077 11.7 0.5 4.6 4 2 1 5 5 5 0 NMDA receptor-regulated protein 1 ParA PF10609.4 EIW70841.1 - 1.2e-30 105.1 0.0 2e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIW70841.1 - 6.7e-10 38.6 0.0 1.3e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIW70841.1 - 1e-05 25.5 0.1 0.00039 20.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EIW70841.1 - 1.9e-05 23.9 0.0 0.00028 20.0 0.0 2.0 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EIW70841.1 - 0.0002 20.5 0.3 0.0019 17.3 0.1 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EIW70841.1 - 0.053 12.9 0.4 0.083 12.2 0.2 1.4 1 1 0 1 1 1 0 AAA domain TRM PF02005.11 EIW70842.1 - 1.3e-120 402.8 0.0 2.4e-90 303.1 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 EIW70842.1 - 0.0091 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EIW70842.1 - 0.012 15.2 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 Met-10+ like-protein ASF1_hist_chap PF04729.8 EIW70843.1 - 2.7e-61 205.7 0.1 3.7e-61 205.2 0.1 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone tRNA-synt_1c PF00749.16 EIW70844.1 - 1.2e-102 342.7 0.0 1.7e-102 342.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EIW70844.1 - 1.2e-34 119.4 0.0 2.2e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 EIW70844.1 - 1e-20 73.9 0.0 1.6e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 EIW70844.1 - 3.5e-06 27.6 0.0 3.5e-06 27.6 0.0 2.4 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Chromo PF00385.19 EIW70845.1 - 0.00017 21.1 2.6 0.00036 20.1 1.8 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIW70845.1 - 0.024 14.3 0.2 0.059 13.0 0.2 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.21 EIW70847.1 - 3e-10 39.8 5.9 9.2e-05 22.5 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW70847.1 - 1.4e-06 28.2 6.4 1.9e-05 24.6 0.1 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW70847.1 - 8.4e-05 22.6 7.1 0.057 13.7 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIW70847.1 - 0.11 12.1 1.7 2.8 7.7 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-CCHC PF00098.18 EIW70848.1 - 0.002 17.9 1.8 0.0032 17.3 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIW70848.1 - 0.024 14.1 0.1 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW70848.1 - 0.85 9.8 8.1 0.15 12.2 2.5 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain CsbD PF05532.7 EIW70850.1 - 0.002 17.7 6.9 0.075 12.7 1.8 2.2 2 0 0 2 2 2 2 CsbD-like DUF4243 PF14027.1 EIW70851.1 - 5.6e-61 206.8 0.0 7.1e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Sulfate_transp PF00916.15 EIW70854.1 - 4.2e-43 147.3 8.5 4.2e-43 147.3 5.9 1.6 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EIW70854.1 - 1.5e-14 53.5 0.0 2.8e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EIW70854.1 - 3.3e-08 32.9 0.0 7.9e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 STAS domain Alpha-amylase PF00128.19 EIW70855.1 - 2.2e-60 204.7 0.0 2.8e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EIW70855.1 - 6.9e-19 67.7 0.0 1.3e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) EMP24_GP25L PF01105.19 EIW70856.1 - 8.5e-44 149.4 0.1 9.6e-44 149.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2213 PF09979.4 EIW70856.1 - 0.061 12.9 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) CarboxypepD_reg PF13620.1 EIW70856.1 - 0.12 12.4 0.3 0.29 11.2 0.1 1.6 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Ran_BP1 PF00638.13 EIW70857.1 - 8e-51 171.1 2.1 1.3e-50 170.5 1.5 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EIW70857.1 - 0.00029 20.5 0.4 0.0016 18.1 0.3 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 EIW70857.1 - 0.062 12.8 0.1 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1681) Thioredoxin PF00085.15 EIW70859.1 - 6.5e-58 192.8 0.0 5.2e-28 96.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EIW70859.1 - 2e-19 69.9 0.0 2e-19 69.9 0.0 2.1 3 0 0 3 3 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EIW70859.1 - 4.1e-17 62.4 0.1 4.7e-08 33.2 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EIW70859.1 - 4.8e-12 45.7 0.0 1.1e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EIW70859.1 - 2.7e-10 40.2 0.0 0.0039 17.2 0.0 3.7 2 2 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EIW70859.1 - 1.1e-08 34.7 0.0 0.0011 18.6 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.8 EIW70859.1 - 1.8e-08 34.3 0.0 0.0028 17.5 0.0 2.6 2 1 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_6 PF13848.1 EIW70859.1 - 2.1e-06 27.6 0.0 0.00071 19.4 0.0 3.6 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EIW70859.1 - 6.7e-06 25.8 0.0 0.0069 16.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_9 PF14595.1 EIW70859.1 - 7.3e-05 22.3 0.0 0.087 12.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 EIW70859.1 - 8e-05 22.2 0.1 0.17 11.4 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 EIW70859.1 - 0.0013 18.7 0.5 1.7 8.6 0.0 2.8 2 1 1 3 3 3 2 Thioredoxin Glutaredoxin PF00462.19 EIW70859.1 - 0.01 15.7 0.5 0.79 9.7 0.2 2.9 2 1 0 2 2 2 0 Glutaredoxin HyaE PF07449.6 EIW70859.1 - 0.015 15.2 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE TraF PF13728.1 EIW70859.1 - 0.072 12.5 0.0 10 5.5 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein zf-C2H2 PF00096.21 EIW70860.1 - 1.2e-09 37.9 10.2 0.00014 22.0 0.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW70860.1 - 3.3e-08 33.4 4.8 3.1e-05 24.0 0.5 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW70860.1 - 7e-08 32.2 5.6 0.00014 21.9 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW70860.1 - 0.0073 16.1 2.9 0.23 11.4 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIW70860.1 - 0.2 11.3 1.4 0.45 10.2 1.0 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type GTP_EFTU PF00009.22 EIW70862.1 - 4.1e-51 173.0 0.0 8.3e-51 172.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EIW70862.1 - 2.8e-16 59.1 0.0 6.6e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EIW70862.1 - 1.2e-08 34.6 0.0 3.3e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EIW70862.1 - 6.1e-05 22.5 0.0 0.0002 20.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 EIW70862.1 - 0.047 13.7 0.1 0.43 10.7 0.1 2.5 1 1 0 1 1 1 0 Elongation factor Tu domain 2 DnaJ PF00226.26 EIW70863.1 - 1.1e-24 85.9 1.5 1.6e-24 85.4 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIW70863.1 - 1.2e-19 69.9 0.0 6.9e-16 57.9 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIW70863.1 - 8.5e-12 44.9 15.8 1.3e-11 44.3 10.9 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EIW70863.1 - 1.1 9.0 7.0 0.7 9.6 1.6 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Alba PF01918.16 EIW70864.1 - 0.00079 18.9 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Alba Cpn60_TCP1 PF00118.19 EIW70865.1 - 2.2e-146 488.2 0.9 2.6e-146 488.0 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FBPase PF00316.15 EIW70866.1 - 4.4e-127 423.3 0.0 5e-127 423.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EIW70866.1 - 0.00023 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Glyco_hydro_16 PF00722.16 EIW70867.1 - 1.6e-09 37.3 0.0 3.3e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Podoplanin PF05808.6 EIW70867.1 - 0.003 17.1 0.2 0.0048 16.4 0.2 1.3 1 0 0 1 1 1 1 Podoplanin Adeno_E3_CR2 PF02439.10 EIW70867.1 - 0.0065 15.9 7.4 0.011 15.2 5.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF2273 PF10031.4 EIW70867.1 - 0.69 9.5 5.9 1.1 8.8 4.1 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Rpn3_C PF08375.6 EIW70868.1 - 6.3e-21 74.5 2.6 1.1e-20 73.7 1.8 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EIW70868.1 - 1.6e-16 60.4 0.0 3.8e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 EIW70868.1 - 0.096 12.6 8.0 0.28 11.1 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW70868.1 - 1.1 10.0 7.6 4.9 8.0 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIW70868.1 - 3.2 7.7 7.9 0.59 10.1 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat p450 PF00067.17 EIW70869.1 - 1.4e-69 234.8 0.0 1.8e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ECR1_N PF14382.1 EIW70870.1 - 6.8e-16 57.2 0.1 1.2e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Abhydrolase_5 PF12695.2 EIW70871.1 - 1.8e-07 30.9 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EIW70871.1 - 1.5e-06 27.6 0.0 2.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EIW70871.1 - 0.00016 21.6 2.3 0.00031 20.7 1.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EIW70871.1 - 0.00043 19.9 0.0 0.00087 18.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EIW70871.1 - 0.005 16.4 0.0 0.0098 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 EIW70871.1 - 0.032 13.3 0.0 0.43 9.6 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.8 EIW70871.1 - 0.046 13.2 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 EIW70871.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) 3Beta_HSD PF01073.14 EIW70872.1 - 1.1e-11 43.9 0.0 1.7e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW70872.1 - 2.4e-11 43.9 0.5 3.1e-10 40.3 0.3 2.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW70872.1 - 8.1e-11 41.7 0.2 9.2e-10 38.3 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIW70872.1 - 5.6e-10 38.5 0.0 1.2e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EIW70872.1 - 4.2e-06 26.7 0.9 2.8e-05 24.1 0.6 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EIW70872.1 - 1.5e-05 24.3 0.1 3.9e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EIW70872.1 - 0.00017 20.5 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EIW70872.1 - 0.00064 19.4 2.0 0.0046 16.6 0.0 2.5 3 0 0 3 3 3 1 KR domain F420_oxidored PF03807.12 EIW70872.1 - 0.042 14.2 0.0 0.12 12.7 0.0 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IF3_C PF00707.17 EIW70872.1 - 0.056 13.1 0.1 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain Dynamin_M PF01031.15 EIW70872.1 - 0.19 10.4 0.0 0.43 9.3 0.0 1.5 1 0 0 1 1 1 0 Dynamin central region Band_7 PF01145.20 EIW70873.1 - 1.6e-23 83.5 2.4 2.3e-23 83.0 1.2 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7 PF01145.20 EIW70874.1 - 2.1e-21 76.6 1.1 3e-21 76.1 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family RGS PF00615.14 EIW70875.1 - 5e-41 139.5 0.4 1.6e-40 137.9 0.2 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 EIW70875.1 - 1.1e-11 44.2 0.0 2.9e-05 23.7 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Zn_clus PF00172.13 EIW70876.1 - 1.3e-10 40.9 11.0 2.3e-10 40.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_decarbox PF01536.11 EIW70877.1 - 4.3e-78 262.3 0.0 6.1e-62 209.2 0.0 4.0 2 2 0 2 2 2 2 Adenosylmethionine decarboxylase Histone PF00125.19 EIW70878.1 - 1.8e-30 104.8 0.3 2.8e-30 104.2 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW70878.1 - 0.001 19.1 0.2 0.0017 18.4 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIW70878.1 - 0.015 15.3 0.6 0.03 14.3 0.4 1.6 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ABC_tran PF00005.22 EIW70879.1 - 3.2e-46 157.0 0.0 1.2e-26 93.6 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW70879.1 - 2.3e-13 50.7 0.8 0.026 14.5 0.1 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EIW70879.1 - 2.1e-11 43.4 0.2 2.3e-06 27.0 0.0 3.3 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EIW70879.1 - 2e-06 27.3 0.0 4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.1 EIW70879.1 - 2.3e-06 28.1 0.4 0.1 12.8 0.2 2.6 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW70879.1 - 5.9e-06 25.7 0.9 0.052 13.0 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain HEAT PF02985.17 EIW70879.1 - 1.4e-05 24.8 1.4 1.1 9.5 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EIW70879.1 - 6.6e-05 23.1 4.1 0.19 12.0 0.2 4.5 2 1 2 4 4 4 2 HEAT repeats DUF87 PF01935.12 EIW70879.1 - 9.6e-05 22.3 0.9 0.078 12.7 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 EIW70879.1 - 0.00017 21.4 0.0 0.065 13.1 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EIW70879.1 - 0.00026 20.2 0.0 0.021 14.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EIW70879.1 - 0.00087 18.8 0.2 0.85 8.9 0.1 3.1 3 0 0 3 3 3 1 AAA-like domain MMR_HSR1 PF01926.18 EIW70879.1 - 0.0016 18.3 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIW70879.1 - 0.0019 18.6 0.0 0.14 12.6 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EIW70879.1 - 0.0022 16.8 2.0 0.079 11.7 0.0 3.0 3 0 0 3 3 3 1 ArgK protein Arm PF00514.18 EIW70879.1 - 0.0026 17.4 0.2 0.017 14.9 0.1 2.5 3 0 0 3 3 1 1 Armadillo/beta-catenin-like repeat NACHT PF05729.7 EIW70879.1 - 0.003 17.2 0.0 1.1 8.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EIW70879.1 - 0.0042 17.2 0.0 3.9 7.6 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.1 EIW70879.1 - 0.0069 15.4 0.1 3.3 6.6 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EIW70879.1 - 0.018 15.8 0.2 6.4 7.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF2880 PF11082.3 EIW70879.1 - 0.026 14.4 0.1 0.077 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) MobB PF03205.9 EIW70879.1 - 0.028 14.1 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B HEAT_EZ PF13513.1 EIW70879.1 - 0.048 14.1 0.1 23 5.6 0.0 3.5 2 0 0 2 2 2 0 HEAT-like repeat AAA_33 PF13671.1 EIW70879.1 - 0.085 12.7 0.1 2 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EIW70879.1 - 0.16 12.1 0.0 6.1 7.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Aldo_ket_red PF00248.16 EIW70880.1 - 1.4e-51 175.0 0.0 1.5e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bravo_FIGEY PF13882.1 EIW70882.1 - 0.016 16.1 0.2 0.024 15.5 0.2 1.3 1 0 0 1 1 1 0 Bravo-like intracellular region DUF605 PF04652.11 EIW70884.1 - 0.44 9.8 6.8 0.46 9.8 4.7 1.0 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 EIW70885.1 - 7.6e-40 133.3 10.3 4e-08 32.8 0.0 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.7 EIW70885.1 - 3e-36 124.6 4.1 3e-36 124.6 2.9 3.3 1 1 1 2 2 2 1 Striatin family Nucleoporin_N PF08801.6 EIW70885.1 - 0.00026 19.8 0.1 1.2 7.7 0.0 3.5 1 1 3 4 4 4 2 Nup133 N terminal like Choline_transpo PF04515.7 EIW70886.1 - 1.6e-77 260.5 18.3 1.6e-77 260.5 12.7 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter tRNA-synt_1g PF09334.6 EIW70887.1 - 5.5e-101 338.0 0.0 6.2e-100 334.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EIW70887.1 - 8.6e-21 73.5 0.4 4.1e-10 38.2 0.2 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EIW70887.1 - 1.4e-11 44.0 0.0 1.3e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EIW70887.1 - 0.0053 16.5 0.1 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.13 EIW70887.1 - 0.017 13.8 0.0 0.049 12.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (K) LSM PF01423.17 EIW70888.1 - 2.8e-19 68.4 0.1 3.2e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIW70888.1 - 0.053 13.4 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain AhpC-TSA_2 PF13911.1 EIW70889.1 - 4.7e-17 61.9 0.0 6.7e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EIW70889.1 - 1.8e-07 30.8 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW70889.1 - 1.3e-06 28.0 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.7 EIW70889.1 - 0.06 12.7 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) DUF3402 PF11882.3 EIW70890.1 - 8.3e-115 384.0 0.7 5.5e-62 210.1 0.2 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.8 EIW70890.1 - 3.4e-36 124.6 0.0 6.2e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein Pex2_Pex12 PF04757.9 EIW70890.1 - 0.093 12.1 0.9 0.36 10.2 0.0 2.2 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region Cyto_heme_lyase PF01265.12 EIW70891.1 - 2.8e-54 184.4 0.1 3e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Fmp27_SW PF10305.4 EIW70893.1 - 0.013 15.9 0.4 0.018 15.4 0.3 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4099 PF13351.1 EIW70893.1 - 0.029 14.2 0.1 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4099) Binary_toxB PF03495.9 EIW70894.1 - 1.7 7.1 8.8 1.9 6.9 6.1 1.1 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA TP6A_N PF04406.9 EIW70895.1 - 3.7e-19 68.1 0.0 1e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Aminotran_1_2 PF00155.16 EIW70896.1 - 9.7e-56 189.2 0.0 2.1e-55 188.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EIW70896.1 - 8.2e-06 24.7 0.0 0.0022 16.8 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EIW70896.1 - 8.4e-05 21.0 0.0 0.0009 17.6 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EIW70896.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EIW70896.1 - 0.00034 19.7 0.0 0.46 9.4 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Epimerase PF01370.16 EIW70897.1 - 0.00046 19.6 0.0 0.00085 18.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW70897.1 - 0.0015 18.5 0.1 0.037 14.0 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW70897.1 - 0.098 11.3 0.0 0.36 9.4 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BAF1_ABF1 PF04684.8 EIW70898.1 - 0.97 8.2 5.9 1.5 7.5 4.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GATA PF00320.22 EIW70899.1 - 7.5e-08 31.5 3.6 1.6e-07 30.5 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger Ribosomal_L6 PF00347.18 EIW70900.1 - 4.5e-25 87.9 1.7 1.5e-13 51.0 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 SH3_9 PF14604.1 EIW70901.1 - 4e-07 29.5 0.0 6.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW70901.1 - 9.7e-05 21.6 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIW70901.1 - 0.00044 19.6 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Shisa PF13908.1 EIW70901.1 - 0.0078 16.4 5.4 0.0078 16.4 3.7 3.7 3 2 0 3 3 3 1 Wnt and FGF inhibitory regulator P12 PF12669.2 EIW70901.1 - 0.047 13.9 1.1 0.087 13.0 0.8 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family Mitofilin PF09731.4 EIW70901.1 - 1.5 7.3 4.9 1.8 7.1 3.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hid1 PF12722.2 EIW70902.1 - 8.5e-143 477.0 0.0 2.2e-142 475.7 0.0 1.5 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EIW70902.1 - 5.7e-59 199.9 0.0 8.4e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Methyltransf_16 PF10294.4 EIW70903.1 - 1.7e-22 79.6 0.0 3.1e-22 78.8 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EIW70903.1 - 0.00084 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW70903.1 - 0.062 13.8 0.0 0.14 12.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain TFIIA PF03153.8 EIW70903.1 - 1.5 8.6 6.9 1.9 8.3 4.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EIW70903.1 - 2.8 6.0 11.4 3.7 5.6 7.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TIP49 PF06068.8 EIW70904.1 - 1e-181 604.0 0.1 1.2e-181 603.8 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EIW70904.1 - 1.5e-10 41.4 0.1 2.2e-07 31.1 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIW70904.1 - 3e-09 36.2 0.2 4.9e-06 25.7 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIW70904.1 - 2.7e-08 34.0 0.1 2e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW70904.1 - 1.7e-06 28.2 0.9 0.021 14.9 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIW70904.1 - 1.9e-06 27.6 0.2 0.00081 19.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EIW70904.1 - 0.00018 20.7 0.4 0.0049 16.0 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EIW70904.1 - 0.00021 20.9 0.1 0.00065 19.3 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EIW70904.1 - 0.00036 19.9 0.2 0.00069 19.0 0.2 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EIW70904.1 - 0.0004 19.8 0.1 0.00075 18.9 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EIW70904.1 - 0.0015 18.5 0.1 0.0068 16.3 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIW70904.1 - 0.0027 18.4 0.1 0.0073 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EIW70904.1 - 0.0041 16.6 0.4 3 7.3 0.0 2.6 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EIW70904.1 - 0.0046 16.8 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW70904.1 - 0.0061 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW70904.1 - 0.009 16.3 0.1 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW70904.1 - 0.016 14.3 0.1 0.031 13.3 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 EIW70904.1 - 0.026 13.6 1.5 0.12 11.5 0.0 2.2 2 1 0 2 2 2 0 KaiC NACHT PF05729.7 EIW70904.1 - 0.029 14.0 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 EIW70904.1 - 0.047 13.7 0.1 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EIW70904.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.10 EIW70904.1 - 0.053 13.3 0.0 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 EIW70904.1 - 0.067 12.1 0.0 5.2 5.9 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_11 PF13086.1 EIW70904.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EIW70904.1 - 0.18 10.4 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PhoH PF02562.11 EIW70904.1 - 0.19 10.9 0.1 0.19 10.9 0.1 2.0 3 0 0 3 3 2 0 PhoH-like protein ArdA PF07275.6 EIW70905.1 - 0.0031 17.7 0.1 0.0094 16.2 0.1 1.8 1 0 0 1 1 1 1 Antirestriction protein (ArdA) E1-E2_ATPase PF00122.15 EIW70907.1 - 1.2e-58 197.8 1.4 1.2e-58 197.8 0.9 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIW70907.1 - 1.1e-43 148.8 6.8 1.1e-43 148.8 4.7 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIW70907.1 - 2.1e-25 90.4 0.0 5.2e-25 89.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW70907.1 - 2.3e-18 65.9 0.0 4.9e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIW70907.1 - 2.7e-12 47.2 0.0 3.2e-11 43.7 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIW70907.1 - 4.3e-12 45.3 0.5 4.9e-11 41.9 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIW70907.1 - 3.2e-05 23.6 0.4 0.0053 16.3 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase EF-hand_7 PF13499.1 EIW70908.1 - 1.7e-17 63.3 0.4 7.1e-08 32.4 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EIW70908.1 - 1.8e-16 58.0 5.8 4.4e-05 22.4 0.1 4.6 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EIW70908.1 - 1.7e-14 52.3 6.4 0.00021 20.8 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EIW70908.1 - 1.1e-10 40.3 3.9 0.0018 17.5 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EIW70908.1 - 6.2e-10 38.5 7.1 0.00068 19.1 0.2 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.1 EIW70908.1 - 0.033 14.0 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.4 EIW70908.1 - 0.15 12.1 0.0 0.15 12.1 0.0 2.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Peptidase_S30 PF01577.11 EIW70908.1 - 0.77 9.1 5.5 0.52 9.6 2.1 1.8 2 0 0 2 2 2 0 Potyvirus P1 protease CRAL_TRIO PF00650.15 EIW70909.1 - 1.5e-14 53.8 0.0 2.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIW70909.1 - 1.6e-09 37.7 0.4 1.6e-09 37.7 0.2 2.1 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain Ribosomal_L34 PF00468.12 EIW70911.1 - 8.5e-18 63.7 13.0 1.4e-17 63.0 9.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Drf_GBD PF06371.8 EIW70912.1 - 4.7e-12 45.6 0.0 2.7e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain EPTP PF03736.12 EIW70912.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 EPTP domain PRP21_like_P PF12230.3 EIW70913.1 - 3.9e-61 206.4 11.3 3.9e-61 206.4 7.8 2.9 3 0 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EIW70913.1 - 2.7e-24 84.5 0.5 3.3e-13 49.0 0.1 2.8 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 EIW70913.1 - 5e-05 22.6 2.7 5.9e-05 22.3 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin family zinc_ribbon_2 PF13240.1 EIW70913.1 - 0.02 14.3 0.5 0.032 13.7 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EIW70913.1 - 0.2 10.8 0.1 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF2407 PF10302.4 EIW70913.1 - 0.29 11.3 0.0 0.29 11.3 0.0 3.8 3 1 0 3 3 3 0 DUF2407 ubiquitin-like domain Sugar_tr PF00083.19 EIW70914.1 - 1.8e-104 349.8 21.4 2e-104 349.6 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW70914.1 - 1.7e-23 82.9 23.2 1.7e-23 82.9 16.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SPRY PF00622.23 EIW70915.1 - 3.1e-12 46.6 1.8 1.5e-10 41.2 0.5 3.0 3 0 0 3 3 3 1 SPRY domain HATPase_c PF02518.21 EIW70916.1 - 9.1e-20 70.4 0.4 2.4e-19 69.1 0.3 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EIW70916.1 - 2.7e-08 33.6 0.0 5.7e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Mating_C PF12737.2 EIW70917.1 - 0.0049 15.8 28.6 0.01 14.7 19.8 1.5 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 MFS_1 PF07690.11 EIW70918.1 - 1.6e-40 138.9 52.5 1.6e-40 138.9 36.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily B12D PF06522.6 EIW70918.1 - 0.088 12.5 2.4 0.48 10.1 0.1 3.2 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Ricin_B_lectin PF00652.17 EIW70919.1 - 2.4e-08 34.0 0.2 6.2e-08 32.7 0.1 1.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIW70919.1 - 0.00066 20.0 0.2 0.0044 17.3 0.0 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIW70920.1 - 2e-10 40.7 1.4 2.4e-10 40.5 1.0 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIW70920.1 - 0.006 16.9 0.5 0.14 12.5 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 EIW70920.1 - 0.1 12.0 0.0 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 Cytolethal distending toxin A/C family NPV_P10 PF05531.7 EIW70921.1 - 0.019 15.1 0.3 0.035 14.3 0.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Rrp15p PF07890.7 EIW70923.1 - 1.4e-19 70.4 5.1 3.4e-19 69.1 3.3 1.9 1 1 0 1 1 1 1 Rrp15p RXT2_N PF08595.6 EIW70923.1 - 0.013 15.2 1.0 0.027 14.2 0.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal FMN_dh PF01070.13 EIW70925.1 - 8.3e-97 324.2 0.0 1.2e-96 323.7 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EIW70925.1 - 1.6e-21 75.8 0.0 2.9e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EIW70925.1 - 1.1e-07 31.1 0.0 1.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EIW70925.1 - 2.8e-05 23.1 2.0 6.9e-05 21.8 1.0 1.8 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EIW70925.1 - 0.00013 21.2 0.0 0.00088 18.5 0.0 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 EIW70925.1 - 0.00017 20.9 0.2 0.035 13.3 0.0 2.6 3 0 0 3 3 3 2 Histidine biosynthesis protein DHO_dh PF01180.16 EIW70925.1 - 0.0095 14.9 0.1 0.018 13.9 0.1 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.9 EIW70925.1 - 0.021 13.8 0.1 0.19 10.7 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG LON PF02190.11 EIW70926.1 - 2.3e-25 89.4 0.0 3.1e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EIW70926.1 - 2.4e-09 37.0 10.3 4.7e-09 36.1 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW70926.1 - 7.8e-09 35.2 10.9 1.5e-08 34.3 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW70926.1 - 4.3e-08 32.7 7.2 7.7e-08 31.8 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW70926.1 - 9.3e-08 31.6 9.5 1.7e-07 30.7 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EIW70926.1 - 1.4e-06 27.9 2.0 2.5e-06 27.1 1.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EIW70926.1 - 1.6e-06 27.7 8.6 2.8e-06 26.9 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIW70926.1 - 2.2e-05 24.2 10.9 6.2e-05 22.7 7.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EIW70926.1 - 0.0021 18.1 3.9 0.0053 16.8 2.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EIW70926.1 - 0.004 16.8 3.2 0.004 16.8 2.2 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EIW70926.1 - 0.011 15.2 6.2 0.021 14.4 4.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EIW70926.1 - 0.023 14.1 8.2 0.048 13.1 5.7 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-Apc11 PF12861.2 EIW70926.1 - 0.054 13.3 1.8 0.12 12.2 1.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ADH_N PF08240.7 EIW70927.1 - 6.6e-26 90.2 0.8 1.3e-25 89.2 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW70927.1 - 1.6e-23 82.6 0.0 2.4e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EIW70927.1 - 0.00014 21.4 0.1 0.00033 20.2 0.0 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EIW70927.1 - 0.0087 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EIW70927.1 - 0.009 16.9 0.0 0.03 15.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PrmA PF06325.8 EIW70927.1 - 0.019 14.0 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIW70927.1 - 0.029 14.9 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIW70927.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EIW70927.1 - 0.055 12.8 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain UDPG_MGDP_dh_N PF03721.9 EIW70927.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MCM PF00493.18 EIW70928.1 - 7e-127 422.7 0.0 9.6e-127 422.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIW70928.1 - 1.1e-21 77.5 0.0 2.6e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIW70928.1 - 6.8e-08 31.9 0.0 1e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIW70928.1 - 0.0026 17.3 0.0 0.0055 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW70928.1 - 0.0033 16.9 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EIW70928.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ricin_B_lectin PF00652.17 EIW70931.1 - 2.8e-05 24.1 0.0 3.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.17 EIW70933.1 - 0.00024 21.1 0.1 0.00058 19.8 0.1 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.17 EIW70934.1 - 0.0027 17.7 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Palm_thioest PF02089.10 EIW70935.1 - 7.4e-46 156.3 0.0 1.1e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 EIW70935.1 - 0.0026 17.6 0.0 0.0045 16.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family MPC PF03650.8 EIW70936.1 - 6.1e-37 126.2 0.3 6.8e-37 126.0 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF3292 PF11696.3 EIW70937.1 - 3.6e-60 203.5 1.7 5.5e-41 140.1 0.1 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) Zn_clus PF00172.13 EIW70938.1 - 0.0063 16.4 12.5 0.0094 15.8 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PepSY_2 PF13670.1 EIW70939.1 - 0.027 14.3 3.7 0.081 12.8 0.2 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Aldo_ket_red PF00248.16 EIW70943.1 - 6.4e-47 159.7 0.0 7.2e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EIW70943.1 - 0.54 10.2 2.5 17 5.5 0.0 3.1 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family zf-CCHC PF00098.18 EIW70944.1 - 0.00022 21.0 1.3 0.00034 20.4 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW70944.1 - 0.06 13.0 0.5 0.19 11.4 0.4 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIW70944.1 - 0.13 12.0 1.3 0.24 11.1 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 EIW70944.1 - 0.97 9.3 6.5 2.6 7.9 4.5 1.8 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF2587 PF10759.4 EIW70945.1 - 0.045 13.1 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Na_Ca_ex PF01699.19 EIW70946.1 - 1.9e-34 118.2 35.6 1.2e-18 67.0 7.4 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF1180 PF06679.7 EIW70946.1 - 7.9 6.3 9.3 52 3.6 2.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Aldo_ket_red PF00248.16 EIW70947.1 - 3.4e-66 222.9 0.0 3.9e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RyR PF02026.11 EIW70947.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 RyR domain Fork_head PF00250.13 EIW70948.1 - 2e-13 50.1 0.0 4.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Fork head domain Aldo_ket_red PF00248.16 EIW70949.1 - 8e-48 162.6 0.0 1e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EIW70949.1 - 0.077 12.9 0.7 5.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Amidase PF01425.16 EIW70951.1 - 4.1e-35 121.5 4.2 2.5e-33 115.6 1.2 2.1 2 0 0 2 2 2 2 Amidase XFP_N PF09364.5 EIW70952.1 - 4e-179 595.0 0.0 5.5e-179 594.6 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EIW70952.1 - 3.6e-89 297.5 0.0 5.4e-89 297.0 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EIW70952.1 - 8.6e-83 276.2 0.0 1.8e-82 275.2 0.0 1.6 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Cyclase PF04199.8 EIW70955.1 - 2.3e-12 46.9 0.3 4e-12 46.1 0.2 1.3 1 1 0 1 1 1 1 Putative cyclase DUF4387 PF14330.1 EIW70957.1 - 9.7e-35 118.8 0.0 4.1e-34 116.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 EIW70957.1 - 8.1e-23 80.4 0.0 2.1e-21 75.8 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) Fungal_trans PF04082.13 EIW70958.1 - 1.5e-09 37.0 0.3 9.2e-09 34.5 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EIW70959.1 - 5.9e-70 236.0 16.5 6.9e-70 235.8 11.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW70959.1 - 1.7e-17 63.1 21.3 4.9e-16 58.3 5.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EIW70959.1 - 0.016 15.2 0.5 0.13 12.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Acetate_kinase PF00871.12 EIW70960.1 - 6.2e-83 278.4 0.0 7.3e-83 278.2 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family RTA1 PF04479.8 EIW70961.1 - 4.7e-36 124.3 0.4 1e-35 123.2 0.0 1.6 1 1 1 2 2 2 1 RTA1 like protein DUF4173 PF13777.1 EIW70961.1 - 0.21 10.8 8.8 1.1 8.5 3.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4173) DUF4131 PF13567.1 EIW70961.1 - 4.9 6.5 11.7 4.7 6.5 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Aldo_ket_red PF00248.16 EIW70962.1 - 3.1e-65 219.8 0.0 3.8e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.23 EIW70964.1 - 5.3e-96 321.5 0.0 6.9e-96 321.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW70964.1 - 1.4e-05 25.8 0.0 0.0001 23.1 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BTB PF00651.26 EIW70965.1 - 5.4e-07 29.5 0.2 1.7e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Collagen PF01391.13 EIW70965.1 - 0.035 13.6 12.1 0.077 12.5 8.4 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Pkinase PF00069.20 EIW70966.1 - 4.7e-41 140.6 0.0 5.2e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW70966.1 - 2e-16 59.8 0.0 2.5e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW70966.1 - 0.04 12.8 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EIW70966.1 - 0.068 12.8 0.7 0.42 10.2 0.4 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sugar_tr PF00083.19 EIW70967.1 - 6.7e-62 209.5 26.6 8.1e-62 209.2 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW70967.1 - 6.7e-19 67.8 24.2 1e-18 67.1 16.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PIRT PF15099.1 EIW70967.1 - 0.2 10.8 1.5 0.44 9.7 1.0 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3605 PF12239.3 EIW70968.1 - 4.6e-27 94.8 0.6 1.4e-10 41.2 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3605) ox_reductase_C PF08635.5 EIW70969.1 - 1.4e-44 150.9 0.0 2.3e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EIW70969.1 - 5.6e-12 46.2 0.0 8.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Homeobox PF00046.24 EIW70970.1 - 5.1e-15 54.8 0.1 1.3e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox domain Syntaxin PF00804.20 EIW70971.1 - 1e-16 60.9 3.6 4.1e-16 59.0 0.1 2.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 EIW70971.1 - 2.8e-14 52.5 1.0 1.2e-13 50.4 0.1 2.5 3 0 0 3 3 3 1 SNARE domain Atg14 PF10186.4 EIW70971.1 - 0.0061 15.5 0.4 2.2 7.1 0.1 2.2 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 zf-C4H2 PF10146.4 EIW70971.1 - 0.013 15.5 0.2 3.1 7.7 0.0 2.4 3 0 0 3 3 3 0 Zinc finger-containing protein NPV_P10 PF05531.7 EIW70971.1 - 0.031 14.5 2.0 0.49 10.6 0.1 3.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.1 EIW70971.1 - 0.032 14.1 0.2 0.032 14.1 0.2 2.7 3 0 0 3 3 3 0 FlxA-like protein Syntaxin-6_N PF09177.6 EIW70971.1 - 0.043 14.2 3.2 0.68 10.3 0.1 2.8 3 1 0 3 3 2 0 Syntaxin 6, N-terminal SF-assemblin PF06705.6 EIW70971.1 - 0.051 12.7 1.9 2.2 7.3 0.1 2.2 2 0 0 2 2 2 0 SF-assemblin/beta giardin FlaC_arch PF05377.6 EIW70971.1 - 0.14 12.0 0.1 1.4 8.9 0.0 2.6 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.4 EIW70971.1 - 0.19 11.8 3.0 7 6.8 0.3 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EIW70971.1 - 0.19 10.8 3.0 4.3 6.4 0.1 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EIW70971.1 - 0.21 11.3 3.4 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EIW70971.1 - 0.28 10.9 2.7 2.8 7.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cluap1 PF10234.4 EIW70971.1 - 0.9 8.6 4.7 1.7 7.7 0.2 2.2 2 0 0 2 2 2 0 Clusterin-associated protein-1 Fib_alpha PF08702.5 EIW70971.1 - 1.7 8.7 4.7 8.1 6.5 0.4 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FliD_N PF02465.13 EIW70971.1 - 4.1 7.8 8.2 2.9 8.2 0.4 3.3 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus LSM PF01423.17 EIW70972.1 - 3.7e-16 58.4 0.0 4.1e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain Serglycin PF04360.7 EIW70973.1 - 0.3 10.7 6.3 0.86 9.3 4.4 1.7 1 0 0 1 1 1 0 Serglycin AAA PF00004.24 EIW70974.1 - 1.3e-43 148.3 0.0 2.3e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW70974.1 - 2.4e-07 30.9 0.0 3e-05 24.0 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EIW70974.1 - 7.9e-07 28.8 0.0 7.3e-06 25.7 0.0 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIW70974.1 - 1.7e-06 28.2 0.0 0.00052 20.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIW70974.1 - 4.4e-06 26.7 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EIW70974.1 - 8.9e-06 24.9 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIW70974.1 - 4.8e-05 23.0 0.0 0.00016 21.3 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_17 PF13207.1 EIW70974.1 - 0.00049 20.9 0.1 0.0015 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EIW70974.1 - 0.0011 18.0 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EIW70974.1 - 0.0023 17.8 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW70974.1 - 0.003 17.4 0.0 0.0066 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EIW70974.1 - 0.0031 16.9 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EIW70974.1 - 0.0035 16.1 0.0 0.0061 15.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EIW70974.1 - 0.0038 16.4 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EIW70974.1 - 0.0046 17.2 0.0 0.016 15.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EIW70974.1 - 0.0049 15.9 0.2 0.016 14.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 EIW70974.1 - 0.0056 16.0 0.3 0.053 12.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 EIW70974.1 - 0.0068 16.3 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EIW70974.1 - 0.0077 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.6 EIW70974.1 - 0.008 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EIW70974.1 - 0.013 15.0 0.1 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EIW70974.1 - 0.016 14.4 0.1 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 EIW70974.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 EIW70974.1 - 0.027 13.9 0.0 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EIW70974.1 - 0.042 13.4 0.0 0.21 11.2 0.0 2.0 1 1 1 2 2 2 0 NACHT domain UPF0079 PF02367.12 EIW70974.1 - 0.048 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EIW70974.1 - 0.05 12.7 0.1 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 EIW70974.1 - 0.053 13.2 0.1 0.2 11.3 0.0 2.1 2 1 0 2 2 1 0 Archaeal ATPase Parvo_NS1 PF01057.12 EIW70974.1 - 0.059 12.2 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 EIW70974.1 - 0.064 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EIW70974.1 - 0.073 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 EIW70974.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_pol_3_Rpc31 PF11705.3 EIW70975.1 - 6.1e-08 32.8 0.6 0.0081 16.1 0.3 2.2 2 0 0 2 2 2 2 DNA-directed RNA polymerase III subunit Rpc31 R3H PF01424.17 EIW70976.1 - 0.0001 21.8 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EIW70976.1 - 0.0096 15.8 11.0 0.0096 15.8 7.6 14.9 15 2 0 15 15 15 9 NF-X1 type zinc finger zf-CCHC PF00098.18 EIW70978.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW70978.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW70978.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Dysbindin PF04440.11 EIW70979.1 - 0.042 13.5 3.9 0.13 12.0 2.7 1.8 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) RVT_2 PF07727.9 EIW70982.1 - 1.1e-72 243.9 0.0 1.7e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Snf7 PF03357.16 EIW70984.1 - 4.6e-15 55.4 16.9 8e-15 54.6 11.7 1.3 1 0 0 1 1 1 1 Snf7 HK97-gp10_like PF04883.7 EIW70984.1 - 0.015 16.1 0.5 0.068 14.1 0.3 2.1 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component DUF445 PF04286.7 EIW70984.1 - 0.022 14.2 7.1 0.033 13.7 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Syntaxin-6_N PF09177.6 EIW70984.1 - 5.2 7.5 9.0 0.98 9.8 0.8 3.0 1 1 1 3 3 3 0 Syntaxin 6, N-terminal TPX2 PF06886.6 EIW70985.1 - 7.7e-05 22.6 9.3 7.7e-05 22.6 6.4 2.8 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) ADH_N PF08240.7 EIW70986.1 - 1.7e-25 88.8 0.6 3.2e-25 88.0 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW70986.1 - 6.6e-14 51.5 0.0 1.1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EIW70986.1 - 0.00048 19.7 0.0 0.00077 19.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EIW70986.1 - 0.0053 16.7 0.0 0.0077 16.2 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain Bro-N PF02498.12 EIW70988.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 BRO family, N-terminal domain Spectrin PF00435.16 EIW70988.1 - 0.22 11.8 1.7 3.4 8.0 1.0 2.6 2 1 1 3 3 3 0 Spectrin repeat DDE_1 PF03184.14 EIW70990.1 - 6e-30 103.9 0.0 9e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW70990.1 - 3.9e-06 26.5 0.3 1.2e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EIW70990.1 - 1.2e-05 24.7 2.7 2e-05 24.0 0.0 2.7 4 0 0 4 4 4 1 helix-turn-helix, Psq domain Tet_JBP PF12851.2 EIW70992.1 - 1.7e-05 24.1 0.0 4.5e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EIW70992.1 - 0.0044 17.5 0.2 0.016 15.7 0.1 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily G-gamma PF00631.17 EIW70992.1 - 0.053 13.2 0.1 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 GGL domain Golgin_A5 PF09787.4 EIW70994.1 - 0.016 13.7 0.3 0.018 13.6 0.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF480 PF04337.7 EIW70994.1 - 0.027 14.3 0.3 0.042 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF480 BioW PF03744.8 EIW70994.1 - 0.084 12.2 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase Ldh_1_C PF02866.13 EIW70994.1 - 0.099 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sel1 PF08238.7 EIW70996.1 - 6.1e-25 87.0 43.0 9.4e-06 26.1 1.8 9.5 9 0 0 9 9 9 5 Sel1 repeat TPR_11 PF13414.1 EIW70996.1 - 3.6e-07 29.7 14.9 0.0019 17.8 0.2 4.9 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.1 EIW70996.1 - 6.2e-06 26.7 20.4 0.00056 20.5 1.8 6.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW70996.1 - 0.00055 19.5 12.5 0.0069 16.1 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIW70996.1 - 0.013 15.3 0.5 0.013 15.3 0.3 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIW70996.1 - 0.013 15.3 1.2 0.013 15.3 0.8 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIW70996.1 - 0.033 14.1 0.7 0.033 14.1 0.5 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW70996.1 - 0.037 13.6 0.1 0.037 13.6 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW70996.1 - 0.069 13.8 0.3 0.069 13.8 0.2 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIW70996.1 - 0.52 10.8 7.8 0.22 12.0 0.2 4.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIW70996.1 - 0.66 10.3 10.2 0.33 11.3 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW70996.1 - 3.3 8.3 11.0 13 6.5 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat bZIP_1 PF00170.16 EIW70997.1 - 1.5e-06 28.0 12.1 3.8e-06 26.7 8.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EIW70997.1 - 0.0041 17.3 7.1 0.0041 17.3 4.9 2.5 2 0 0 2 2 2 1 bZIP Maf transcription factor V_ATPase_I PF01496.14 EIW70997.1 - 4.4 5.0 3.3 7.2 4.3 2.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family His_Phos_1 PF00300.17 EIW70999.1 - 0.17 11.9 0.9 15 5.6 0.0 2.5 1 1 2 3 3 3 0 Histidine phosphatase superfamily (branch 1) Ycf1 PF05758.7 EIW71001.1 - 0.5 8.0 5.7 0.78 7.3 4.0 1.2 1 0 0 1 1 1 0 Ycf1 Ribosomal_L5_C PF00673.16 EIW71002.1 - 3.5e-23 81.1 0.0 5.2e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EIW71002.1 - 1.8e-20 72.4 0.0 3.6e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Zn_clus PF00172.13 EIW71003.1 - 0.0012 18.6 16.2 0.0018 18.1 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TOH_N PF12549.3 EIW71006.1 - 1.3 8.6 6.3 3.6 7.2 4.4 1.8 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal PepSY_2 PF13670.1 EIW71007.1 - 0.083 12.7 0.6 0.14 12.0 0.4 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Ashwin PF15323.1 EIW71007.1 - 0.084 12.8 2.7 0.13 12.2 1.8 1.2 1 0 0 1 1 1 0 Developmental protein SR-25 PF10500.4 EIW71007.1 - 0.35 10.3 17.1 0.69 9.3 11.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.5 EIW71007.1 - 1.1 8.1 3.6 1.6 7.7 2.5 1.1 1 0 0 1 1 1 0 BUD22 zf-CCHC PF00098.18 EIW71008.1 - 0.0027 17.5 1.5 0.0049 16.7 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle B56 PF01603.15 EIW71008.1 - 3.1 6.3 2.3 4.2 5.8 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) RVT_1 PF00078.22 EIW71009.1 - 1.2e-19 70.5 0.0 2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3600 PF12207.3 EIW71009.1 - 0.012 15.2 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) TraC_F_IV PF11130.3 EIW71011.1 - 0.032 13.6 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Oxysterol_BP PF01237.13 EIW71012.1 - 2.7e-48 164.2 0.0 4.7e-38 130.5 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein tRNA_U5-meth_tr PF05958.6 EIW71013.1 - 2.6e-15 55.9 0.0 4.2e-14 52.0 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 EIW71013.1 - 1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EIW71013.1 - 5.8e-07 29.5 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EIW71013.1 - 1e-06 28.2 0.0 2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EIW71013.1 - 5.1e-06 26.1 0.0 1.5e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIW71013.1 - 0.00013 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EIW71013.1 - 0.00025 20.2 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIW71013.1 - 0.00038 21.0 0.0 0.00083 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EIW71013.1 - 0.0006 19.4 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EIW71013.1 - 0.032 13.8 0.0 0.09 12.3 0.0 1.7 2 0 0 2 2 2 0 Met-10+ like-protein Ubie_methyltran PF01209.13 EIW71013.1 - 0.061 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EIW71013.1 - 0.07 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Synaptobrevin PF00957.16 EIW71014.1 - 5.6e-28 96.3 3.8 6.3e-28 96.2 2.6 1.0 1 0 0 1 1 1 1 Synaptobrevin Scaffolding_pro PF11418.3 EIW71014.1 - 0.00079 19.6 0.1 0.00092 19.4 0.0 1.1 1 0 0 1 1 1 1 Phi29 scaffolding protein CCDC144C PF14915.1 EIW71014.1 - 0.035 13.0 2.1 0.04 12.8 1.5 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region NPV_P10 PF05531.7 EIW71014.1 - 0.047 13.9 0.3 0.053 13.7 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2207 PF09972.4 EIW71014.1 - 0.061 11.8 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SecD-TM1 PF13721.1 EIW71014.1 - 0.83 9.9 6.0 4.9 7.4 0.2 2.1 2 0 0 2 2 2 0 SecD export protein N-terminal TM region OmpH PF03938.9 EIW71014.1 - 0.88 9.4 5.8 1.1 9.1 4.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.8 EIW71014.1 - 1.5 8.2 9.2 0.13 11.5 1.1 2.0 1 1 1 2 2 2 0 fzo-like conserved region Clathrin PF00637.15 EIW71015.1 - 2.7e-195 639.7 27.4 4.5e-31 107.3 0.5 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 EIW71015.1 - 9.2e-29 97.7 2.2 0.012 15.8 0.1 7.8 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 EIW71015.1 - 2.6e-27 94.4 0.1 6.6e-27 93.1 0.1 1.8 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 EIW71015.1 - 1.8e-11 42.8 0.3 5.2e-11 41.3 0.2 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Vps39_1 PF10366.4 EIW71015.1 - 5.6e-05 23.1 3.1 1.1 9.3 0.0 5.3 4 1 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Coatomer_WDAD PF04053.9 EIW71015.1 - 0.0028 16.5 5.0 1.2 7.7 0.0 4.1 4 0 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.23 EIW71015.1 - 0.0062 16.0 3.4 20 5.0 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIW71015.1 - 0.066 13.1 3.4 47 4.2 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Sigma70_ner PF04546.8 EIW71018.1 - 0.36 10.4 7.2 0.57 9.7 1.4 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Homoserine_dh PF00742.14 EIW71019.1 - 6.8e-51 172.4 0.0 8.9e-51 172.0 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EIW71019.1 - 1.1e-10 41.9 0.0 3e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Mtc PF03820.12 EIW71020.1 - 4.6e-83 278.3 0.0 5.7e-83 278.1 0.0 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier Rad60-SLD_2 PF13881.1 EIW71022.1 - 1.3e-14 53.9 0.0 1.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIW71022.1 - 7.5e-05 22.0 0.0 0.015 14.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family DUF2407 PF10302.4 EIW71022.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.6 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Metallophos PF00149.23 EIW71023.1 - 1.2e-09 37.8 0.1 3.1e-09 36.5 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW71023.1 - 3.8e-07 30.0 0.1 7.4e-07 29.1 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Scytalone_dh PF02982.9 EIW71023.1 - 0.037 13.6 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 Scytalone dehydratase Ion_trans_2 PF07885.11 EIW71024.1 - 3.2e-32 110.0 30.9 1.9e-19 69.1 9.1 3.0 3 0 0 3 3 3 2 Ion channel CCER1 PF15482.1 EIW71024.1 - 0.047 13.3 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 adh_short_C2 PF13561.1 EIW71025.1 - 4.2e-25 88.9 0.1 4.6e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW71025.1 - 4e-18 65.8 0.0 4.9e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW71025.1 - 0.00015 21.4 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 KR domain LSM PF01423.17 EIW71026.1 - 8.3e-17 60.5 0.1 9.9e-17 60.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF2442 PF10387.4 EIW71026.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) Fungal_trans PF04082.13 EIW71028.1 - 4.1e-14 52.0 0.0 8.7e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EIW71030.1 - 2.2e-08 33.3 0.1 4.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW71030.1 - 5.8e-05 22.9 11.5 0.00011 22.0 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tht1 PF04163.7 EIW71032.1 - 0.019 13.4 3.5 0.081 11.3 2.4 2.1 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein Shufflon_N PF04917.7 EIW71032.1 - 0.039 13.0 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region Reo_sigmaC PF04582.7 EIW71032.1 - 2.1 7.4 14.1 1.7 7.7 0.6 3.4 3 0 0 3 3 3 0 Reovirus sigma C capsid protein zf-DHHC PF01529.15 EIW71033.1 - 5.7e-39 133.2 0.2 1.9e-38 131.6 0.1 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF4199 PF13858.1 EIW71033.1 - 0.0037 17.2 1.2 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) DUF1282 PF06930.7 EIW71033.1 - 0.41 10.2 4.8 0.39 10.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) GATA PF00320.22 EIW71034.1 - 3.1e-16 58.3 4.6 4.1e-16 58.0 3.2 1.2 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.5 EIW71034.1 - 0.0078 16.1 0.4 0.01 15.7 0.3 1.2 1 0 0 1 1 1 1 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 EIW71034.1 - 0.032 13.8 0.6 0.046 13.3 0.4 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 zf-Sec23_Sec24 PF04810.10 EIW71034.1 - 0.057 12.9 0.9 0.076 12.5 0.6 1.2 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger TF_Zn_Ribbon PF08271.7 EIW71034.1 - 0.096 12.0 1.0 0.15 11.3 0.7 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Nudix_N_2 PF14803.1 EIW71034.1 - 0.099 12.3 2.9 0.25 11.0 2.0 1.7 1 1 0 1 1 1 0 Nudix N-terminal Zn_Tnp_IS1595 PF12760.2 EIW71034.1 - 0.11 12.3 1.4 0.16 11.8 1.0 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.2 EIW71034.1 - 0.18 11.6 2.7 0.37 10.6 1.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 EIW71034.1 - 0.25 11.0 1.3 0.33 10.6 0.9 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EIW71034.1 - 0.27 10.5 4.0 0.99 8.6 2.8 1.8 1 1 0 1 1 1 0 zinc-ribbon domain RhoGAP PF00620.22 EIW71035.1 - 1.6e-39 134.9 0.0 3.2e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EIW71035.1 - 1e-10 41.7 0.0 4.1e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EIW71035.1 - 4.6e-07 30.0 0.0 1.3e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PX PF00787.19 EIW71035.1 - 9e-07 28.6 0.0 2.6e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 PX domain DUF1418 PF07214.7 EIW71035.1 - 0.065 12.8 0.0 0.22 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) ESCRT-II PF05871.7 EIW71036.1 - 3.1e-43 147.0 0.2 4.7e-43 146.4 0.1 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit Tetraspannin PF00335.15 EIW71037.1 - 0.00013 21.3 12.7 0.00017 20.9 8.8 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF4336 PF14234.1 EIW71039.1 - 0.00026 20.2 0.0 0.0045 16.1 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4336) DUF374 PF04028.8 EIW71039.1 - 0.096 11.9 0.0 0.23 10.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF374) Rxt3 PF08642.5 EIW71040.1 - 1.3e-22 80.1 0.7 5.8e-21 74.8 0.5 2.8 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EIW71040.1 - 2.4e-05 24.2 0.0 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 LCCL domain Zip PF02535.17 EIW71040.1 - 3.1 6.7 7.5 6 5.7 5.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter She9_MDM33 PF05546.6 EIW71043.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family DER1 PF04511.10 EIW71044.1 - 1.1e-33 116.4 4.7 1.3e-33 116.1 3.2 1.0 1 0 0 1 1 1 1 Der1-like family NUDIX PF00293.23 EIW71045.1 - 1e-10 41.3 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.24 EIW71046.1 - 1.9e-96 319.2 0.0 7.6e-47 158.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EIW71046.1 - 2.9e-18 65.5 0.6 3.7e-17 62.0 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EIW71046.1 - 4.1e-14 52.1 0.1 2.4e-05 23.4 0.0 3.7 3 2 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EIW71046.1 - 1.5e-13 50.8 0.0 7e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EIW71046.1 - 2.9e-13 50.0 0.0 3.4e-07 30.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIW71046.1 - 1.3e-12 47.5 0.4 3.7e-06 26.7 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIW71046.1 - 6.9e-12 46.2 0.1 0.0005 20.8 0.0 3.6 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.1 EIW71046.1 - 2.2e-11 43.9 0.1 0.0013 18.8 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIW71046.1 - 2.3e-09 37.4 0.0 0.0054 16.7 0.0 3.2 2 2 1 3 3 2 2 AAA ATPase domain TIP49 PF06068.8 EIW71046.1 - 3.1e-09 36.0 0.0 0.0014 17.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 EIW71046.1 - 1.1e-08 34.4 0.0 0.0048 16.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 EIW71046.1 - 3.3e-08 33.1 0.0 0.0031 16.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 EIW71046.1 - 6.1e-08 32.3 2.2 0.0056 16.1 0.0 3.6 2 2 1 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EIW71046.1 - 6.7e-08 31.9 0.4 0.0042 16.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIW71046.1 - 1.1e-07 31.7 0.0 0.0063 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EIW71046.1 - 1.2e-07 31.2 0.0 2.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.1 EIW71046.1 - 2e-07 30.6 0.9 0.018 14.7 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain Vps4_C PF09336.5 EIW71046.1 - 6.3e-07 29.1 0.1 5.2e-06 26.2 0.0 2.6 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 EIW71046.1 - 1.3e-06 28.5 0.0 0.014 15.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EIW71046.1 - 3.6e-06 27.2 0.0 0.042 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 EIW71046.1 - 4.1e-06 25.8 0.1 0.0042 15.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EIW71046.1 - 4.4e-06 26.7 0.0 0.056 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EIW71046.1 - 5.9e-06 26.2 0.0 0.0079 16.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit KaiC PF06745.8 EIW71046.1 - 7.7e-06 25.1 1.3 0.88 8.6 0.1 3.8 3 1 1 4 4 3 2 KaiC Sigma54_activat PF00158.21 EIW71046.1 - 1e-05 25.0 0.0 0.3 10.5 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 EIW71046.1 - 1.3e-05 24.9 0.1 0.066 12.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain Sigma54_activ_2 PF14532.1 EIW71046.1 - 1.8e-05 24.7 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EIW71046.1 - 2.1e-05 24.8 0.0 0.068 13.4 0.0 3.3 2 1 0 2 2 2 1 ABC transporter DUF815 PF05673.8 EIW71046.1 - 2.4e-05 23.3 0.0 0.011 14.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EIW71046.1 - 4.1e-05 22.9 0.2 0.28 10.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.7 EIW71046.1 - 4.4e-05 23.1 0.1 0.068 12.8 0.0 3.5 4 0 0 4 4 3 1 NACHT domain Bac_DnaA PF00308.13 EIW71046.1 - 0.0001 22.0 0.0 0.56 9.8 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein Arch_ATPase PF01637.13 EIW71046.1 - 0.00012 21.9 0.0 1.7 8.2 0.0 3.4 2 1 1 3 3 3 1 Archaeal ATPase AAA_11 PF13086.1 EIW71046.1 - 0.00012 21.7 0.0 0.34 10.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EIW71046.1 - 0.00013 21.5 0.0 0.41 10.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EIW71046.1 - 0.00039 20.0 0.0 0.61 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EIW71046.1 - 0.0017 17.9 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EIW71046.1 - 0.0019 17.1 0.1 0.16 10.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 EIW71046.1 - 0.0029 17.3 0.2 0.73 9.5 0.0 3.4 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 EIW71046.1 - 0.0031 16.5 1.1 0.88 8.4 0.0 2.6 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EIW71046.1 - 0.0045 16.4 1.3 1.1 8.5 0.0 3.8 3 1 1 4 4 4 1 AAA-like domain T2SE PF00437.15 EIW71046.1 - 0.0059 15.5 0.0 0.22 10.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein IPT PF01745.11 EIW71046.1 - 0.019 14.1 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 EIW71046.1 - 0.023 14.3 0.1 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EIW71046.1 - 0.036 13.2 0.0 4.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SKI PF01202.17 EIW71046.1 - 0.042 13.7 0.3 6.8 6.5 0.0 3.1 4 0 0 4 4 2 0 Shikimate kinase KAP_NTPase PF07693.9 EIW71046.1 - 0.051 12.5 0.0 1 8.3 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain MobB PF03205.9 EIW71046.1 - 0.075 12.7 0.5 5.1 6.7 0.0 3.4 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EIW71046.1 - 0.079 12.4 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AFG1_ATPase PF03969.11 EIW71046.1 - 0.08 11.7 0.0 8.3 5.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_23 PF13476.1 EIW71046.1 - 0.11 12.8 0.1 0.94 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain CENP-B_dimeris PF09026.5 EIW71046.1 - 0.76 10.0 5.8 2.1 8.6 3.7 1.9 2 0 0 2 2 1 0 Centromere protein B dimerisation domain DSPc PF00782.15 EIW71047.1 - 4e-05 23.2 0.0 7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EIW71047.1 - 0.023 14.9 0.0 0.061 13.5 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 EIW71047.1 - 0.06 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.7 EIW71047.1 - 0.2 11.0 0.0 0.5 9.8 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) FHA PF00498.21 EIW71048.1 - 6.7e-17 61.3 0.0 1.1e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF4404 PF14357.1 EIW71048.1 - 0.19 12.1 2.0 32 5.0 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) RNase_PH PF01138.16 EIW71049.1 - 2.8e-26 92.3 0.0 5e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Tom22 PF04281.8 EIW71050.1 - 2.4e-36 124.3 0.1 2.5e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 ABC1 PF03109.11 EIW71051.1 - 3.5e-30 104.4 0.0 6.5e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EIW71051.1 - 1.1e-05 24.8 0.1 7e-05 22.2 0.1 2.1 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 EIW71051.1 - 0.068 12.8 0.4 2.5 7.7 0.3 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EIW71051.1 - 0.069 12.2 0.2 0.21 10.7 0.1 1.7 1 1 0 1 1 1 0 Protein kinase domain PQ-loop PF04193.9 EIW71052.1 - 2.9e-23 81.1 3.2 1e-10 40.9 0.9 2.6 2 0 0 2 2 2 2 PQ loop repeat Mem_trans PF03547.13 EIW71054.1 - 4.4e-36 124.0 6.2 6.6e-36 123.4 4.3 1.2 1 0 0 1 1 1 1 Membrane transport protein RRM_1 PF00076.17 EIW71056.1 - 2.6e-21 75.0 0.0 2.9e-15 55.6 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW71056.1 - 1.2e-15 57.2 0.0 2.2e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW71056.1 - 6.8e-10 38.6 0.0 0.0001 22.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIW71056.1 - 0.11 12.2 0.0 15 5.4 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 DbpA PF03880.10 EIW71056.1 - 0.16 11.6 0.0 17 5.1 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain LRR_4 PF12799.2 EIW71057.1 - 6e-13 48.0 8.4 5.7e-10 38.5 1.7 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW71057.1 - 5.7e-09 35.6 0.9 2e-08 33.8 0.6 2.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_7 PF13504.1 EIW71057.1 - 2.3e-05 23.8 5.1 0.04 14.0 1.0 4.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EIW71057.1 - 4.7e-05 22.8 7.3 0.086 12.9 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 EIW71057.1 - 0.0018 18.1 0.6 2 8.7 0.0 3.1 2 0 0 2 2 2 2 Leucine Rich repeat PyrBI_leader PF08052.6 EIW71057.1 - 0.0043 16.8 0.9 0.43 10.4 0.0 3.0 3 0 0 3 3 3 1 PyrBI operon leader peptide Ras PF00071.17 EIW71059.1 - 3.3e-52 176.1 0.0 4e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW71059.1 - 2.5e-18 66.6 0.0 3.3e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW71059.1 - 4.2e-10 39.1 0.0 6e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW71059.1 - 1.7e-06 27.3 0.0 2.1e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIW71059.1 - 9.5e-05 21.6 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EIW71059.1 - 0.00036 20.0 0.1 0.0015 17.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW71059.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase IL8 PF00048.15 EIW71059.1 - 0.073 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like DUF2205 PF10224.4 EIW71062.1 - 7.4e-15 54.2 0.1 1.8e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF563 PF04577.9 EIW71062.1 - 2.8e-09 37.1 0.0 4.9e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FH2 PF02181.18 EIW71063.1 - 5.7e-65 219.6 6.7 5.7e-65 219.6 4.7 2.1 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EIW71063.1 - 3.8e-35 120.9 0.0 1e-34 119.5 0.0 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EIW71063.1 - 4.9e-27 94.6 0.2 6.4e-26 90.9 0.0 2.6 2 0 0 2 2 2 1 Diaphanous FH3 Domain WD40 PF00400.27 EIW71064.1 - 4e-10 39.1 6.8 0.0065 16.3 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat SRA1 PF07304.6 EIW71064.1 - 1.4e-05 24.8 0.0 1.4e-05 24.8 0.0 3.1 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 EIW71064.1 - 0.011 15.5 0.6 0.02 14.7 0.0 1.6 2 0 0 2 2 2 0 Prp18 domain Apc4_WD40 PF12894.2 EIW71064.1 - 0.18 11.3 0.1 2 8.0 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.2 EIW71064.1 - 0.2 11.3 0.1 0.67 9.6 0.0 1.8 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 Arrestin_C PF02752.17 EIW71065.1 - 4.1e-05 23.7 0.0 0.29 11.2 0.0 2.8 4 0 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 EIW71066.1 - 2.8e-39 134.8 0.0 8.6e-39 133.2 0.0 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HemY_N PF07219.8 EIW71066.1 - 0.0012 18.4 1.1 0.0012 18.4 0.8 2.6 2 1 0 2 2 2 1 HemY protein N-terminus GPP34 PF05719.6 EIW71067.1 - 4.8e-67 226.0 1.3 5.6e-67 225.7 0.9 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Zn_clus PF00172.13 EIW71068.1 - 4.2e-09 36.1 8.1 6.6e-09 35.5 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MKT1_C PF12246.3 EIW71069.1 - 3.5e-63 212.8 0.0 1.1e-62 211.1 0.0 1.8 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EIW71069.1 - 1.3e-22 79.9 0.0 2.7e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 EIW71069.1 - 3e-09 37.0 0.0 7.6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EIW71069.1 - 3.4e-07 30.2 0.0 6.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region JAB PF01398.16 EIW71070.1 - 6.6e-25 87.0 0.1 1.2e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EIW71070.1 - 1.8e-06 27.4 0.0 3.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain HLH PF00010.21 EIW71071.1 - 0.00039 20.0 0.0 0.0013 18.4 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SLT PF01464.15 EIW71072.1 - 3.3e-13 49.1 0.6 8.4e-13 47.8 0.4 1.7 1 0 0 1 1 1 1 Transglycosylase SLT domain Herpes_capsid PF06112.6 EIW71072.1 - 0.93 9.5 11.8 2 8.4 8.2 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3184 PF11380.3 EIW71073.1 - 0.036 12.0 0.7 0.44 8.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3184) tRNA-synt_2d PF01409.15 EIW71074.1 - 6.5e-89 297.3 0.0 9.7e-89 296.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EIW71074.1 - 2.4e-05 23.9 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EIW71074.1 - 0.0001 21.1 0.0 0.0017 17.2 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Rio2_N PF09202.6 EIW71074.1 - 0.029 14.4 0.1 0.41 10.7 0.0 2.4 2 0 0 2 2 2 0 Rio2, N-terminal Glyco_hydro_16 PF00722.16 EIW71075.1 - 2.7e-09 36.5 0.5 6e-09 35.4 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Thiol-ester_cl PF10569.4 EIW71075.1 - 0.085 12.0 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region CDC27 PF09507.5 EIW71076.1 - 0.17 11.0 46.7 0.14 11.3 29.1 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 hDGE_amylase PF14701.1 EIW71077.1 - 3.9e-149 497.1 0.0 5.4e-149 496.6 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EIW71077.1 - 5.6e-113 377.4 0.0 7.8e-113 376.9 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EIW71077.1 - 1.1e-82 277.1 0.0 1.7e-82 276.5 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EIW71077.1 - 6.2e-17 61.2 0.0 1.1e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EIW71077.1 - 0.14 11.4 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase, catalytic domain BSP PF04450.7 EIW71078.1 - 1.4e-31 109.5 0.0 1e-28 100.2 0.0 2.1 2 0 0 2 2 2 2 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EIW71078.1 - 4.8e-08 33.0 0.0 8.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Ribosomal_L44 PF00935.14 EIW71079.1 - 4.6e-36 122.6 12.7 6.5e-36 122.1 8.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 DUF2652 PF10851.3 EIW71079.1 - 0.14 12.1 0.4 0.14 12.1 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2652) Ribosomal_S13 PF00416.17 EIW71080.1 - 2.7e-38 130.6 1.8 3.2e-38 130.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EIW71080.1 - 0.01 14.3 0.0 0.017 13.6 0.0 1.2 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EIW71080.1 - 0.017 15.1 0.1 0.056 13.4 0.0 1.9 2 1 0 2 2 2 0 Helix-hairpin-helix motif tRNA-synt_1b PF00579.20 EIW71081.1 - 4.4e-70 236.1 0.0 5.6e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Sedlin_N PF04628.8 EIW71082.1 - 7.7e-41 139.0 0.0 1.6e-40 138.0 0.0 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EIW71082.1 - 6.9e-06 25.8 0.0 9.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family ATP-synt_C PF00137.16 EIW71083.1 - 6.1e-31 106.1 24.9 8.7e-18 63.9 5.8 2.4 2 0 0 2 2 2 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 EIW71083.1 - 0.8 9.9 2.3 1 9.6 0.4 2.0 2 0 0 2 2 2 0 G0/G1 switch protein 2 Ran_BP1 PF00638.13 EIW71084.1 - 1.3e-17 63.9 0.0 2.4e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Fungal_trans PF04082.13 EIW71088.1 - 2.1e-15 56.3 0.4 4.1e-15 55.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW71088.1 - 3.7e-07 29.9 11.0 8.4e-07 28.8 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain cobW PF02492.14 EIW71089.1 - 1.5e-32 112.4 0.0 2.1e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EIW71089.1 - 0.0014 18.3 0.1 0.0054 16.4 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.9 EIW71089.1 - 0.0078 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_11 PF13086.1 EIW71089.1 - 0.12 11.9 0.0 0.41 10.1 0.0 1.5 1 1 1 2 2 2 0 AAA domain Oxidored-like PF09791.4 EIW71090.1 - 2.9e-15 55.4 1.2 7.7e-15 54.0 0.8 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal adh_short PF00106.20 EIW71090.1 - 6.5e-07 29.4 0.1 2.2e-05 24.4 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase Iso_dh PF00180.15 EIW71091.1 - 3.2e-76 256.5 0.0 3.9e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SIR2 PF02146.12 EIW71092.1 - 7.7e-57 191.8 0.0 1.2e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EIW71092.1 - 0.00087 19.0 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.8 EIW71092.1 - 0.0055 16.2 0.1 0.028 13.9 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF592) Zn_Tnp_IS91 PF14319.1 EIW71092.1 - 0.038 13.5 1.3 0.066 12.7 0.9 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain Herpes_LMP1 PF05297.6 EIW71093.1 - 0.53 9.1 5.3 0.96 8.3 3.7 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FYVE PF01363.16 EIW71094.1 - 7.9e-21 73.7 1.4 1.5e-20 72.8 1.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger HypA PF01155.14 EIW71094.1 - 0.0092 15.6 0.3 0.0092 15.6 0.2 1.9 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-DHHC PF01529.15 EIW71094.1 - 0.034 13.5 0.2 0.08 12.3 0.0 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase Methyltransf_23 PF13489.1 EIW71095.1 - 1.2e-14 54.3 0.0 2.1e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW71095.1 - 1.2e-11 44.9 0.0 1.1e-10 41.7 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW71095.1 - 8.6e-09 35.9 0.0 2.1e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW71095.1 - 1.3e-08 35.2 0.0 0.0013 19.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EIW71095.1 - 5.3e-07 29.9 0.0 4.5e-06 26.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW71095.1 - 2.6e-06 27.0 0.0 0.0027 17.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EIW71095.1 - 6.4e-05 22.0 0.0 0.27 10.1 0.0 2.1 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 EIW71095.1 - 9.7e-05 22.3 0.0 0.00027 20.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIW71095.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EIW71095.1 - 0.016 14.3 0.0 0.76 8.8 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CheR PF01739.13 EIW71095.1 - 0.021 14.1 0.0 0.33 10.1 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Glu_synthase PF01645.12 EIW71096.1 - 2.6e-155 516.9 0.2 7.8e-155 515.3 0.0 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EIW71096.1 - 1.6e-135 451.4 0.0 2.2e-135 451.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EIW71096.1 - 4.3e-113 377.3 0.0 8.8e-113 376.3 0.0 1.5 2 0 0 2 2 1 1 Glutamate synthase central domain GXGXG PF01493.14 EIW71096.1 - 4.1e-67 225.0 0.6 7.6e-67 224.2 0.4 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EIW71096.1 - 9.1e-22 76.7 0.1 9.1e-22 76.7 0.1 2.0 2 0 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EIW71096.1 - 2.6e-19 69.8 0.2 1.1e-18 67.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW71096.1 - 4.6e-11 43.1 0.7 2.2e-05 24.6 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW71096.1 - 2.5e-08 33.8 0.0 1e-07 31.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW71096.1 - 3.6e-07 30.5 3.3 4.7e-05 23.7 0.2 3.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIW71096.1 - 3.6e-07 29.6 0.1 5.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EIW71096.1 - 4.6e-05 22.0 0.1 4.6e-05 22.0 0.1 2.0 3 0 0 3 3 3 1 HI0933-like protein DJ-1_PfpI PF01965.19 EIW71096.1 - 6.8e-05 22.3 0.1 0.0052 16.2 0.0 2.4 1 1 1 2 2 2 2 DJ-1/PfpI family DAO PF01266.19 EIW71096.1 - 0.00025 20.0 0.2 0.00025 20.0 0.1 3.1 3 1 0 4 4 4 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EIW71096.1 - 0.00053 19.1 0.1 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EIW71096.1 - 0.00056 20.1 0.6 0.21 11.8 0.1 3.1 3 0 0 3 3 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EIW71096.1 - 0.00057 19.4 0.1 0.0023 17.5 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EIW71096.1 - 0.00062 18.7 0.1 0.00062 18.7 0.1 3.1 3 1 0 4 4 3 1 FAD binding domain FAD_binding_3 PF01494.14 EIW71096.1 - 0.0013 17.8 0.0 0.0029 16.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW71096.1 - 0.0066 15.5 0.3 0.0066 15.5 0.2 1.9 2 0 0 2 2 2 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 EIW71096.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.1 EIW71096.1 - 0.02 14.8 0.1 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain FMO-like PF00743.14 EIW71096.1 - 0.031 12.4 0.0 0.14 10.3 0.0 2.0 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.14 EIW71096.1 - 0.065 12.3 0.3 0.34 10.0 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EIW71096.1 - 0.071 11.9 3.2 0.23 10.2 0.2 2.7 2 1 1 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EIW71096.1 - 0.083 12.9 0.2 18 5.4 0.0 2.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EIW71096.1 - 0.12 12.0 1.3 0.34 10.6 0.1 2.5 2 1 1 3 3 2 0 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.16 EIW71096.1 - 0.23 11.2 2.6 10 5.9 0.0 2.9 3 0 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMN_dh PF01070.13 EIW71096.1 - 1 8.1 12.0 0.021 13.7 0.6 3.2 4 0 0 4 4 4 0 FMN-dependent dehydrogenase BolA PF01722.13 EIW71097.1 - 4.6e-29 100.1 0.3 5.4e-29 99.9 0.2 1.1 1 0 0 1 1 1 1 BolA-like protein LRR_6 PF13516.1 EIW71098.1 - 0.00061 19.5 20.8 0.91 9.7 0.1 5.9 5 1 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.2 EIW71098.1 - 0.0011 18.5 20.2 0.021 14.4 0.8 4.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) F-box-like_2 PF13013.1 EIW71098.1 - 0.0027 17.4 0.1 0.01 15.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like domain LRR_1 PF00560.28 EIW71098.1 - 0.23 11.6 0.2 0.23 11.6 0.1 6.3 6 2 0 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 EIW71098.1 - 2.3 8.8 15.4 1.9 9.0 0.0 5.8 6 0 0 6 6 6 0 Leucine rich repeat Amidase PF01425.16 EIW71099.1 - 3.8e-64 217.1 0.0 5.6e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Amidase COesterase PF00135.23 EIW71100.1 - 1.4e-104 350.7 0.0 2.2e-104 350.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW71100.1 - 0.00029 20.4 0.1 0.00054 19.5 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIW71101.1 - 4.4e-102 342.5 0.0 5.7e-102 342.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW71101.1 - 4e-07 29.8 0.1 1.3e-06 28.1 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW71101.1 - 0.019 14.7 0.4 0.031 14.0 0.3 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW71101.1 - 0.065 12.4 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DnaJ PF00226.26 EIW71102.1 - 1.9e-12 46.7 0.0 3.7e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 DnaJ domain COesterase PF00135.23 EIW71103.1 - 1.9e-100 337.1 0.0 2.4e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW71103.1 - 3.1e-06 26.9 0.1 5.6e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW71103.1 - 0.055 12.6 0.1 0.092 11.9 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DnaJ PF00226.26 EIW71104.1 - 4.2e-16 58.4 0.3 4.2e-16 58.4 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain Pkinase PF00069.20 EIW71105.1 - 6.7e-09 35.2 0.0 1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71105.1 - 0.00078 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DS PF01916.12 EIW71106.1 - 7e-126 419.3 0.0 5.4e-123 409.8 0.0 2.0 1 1 1 2 2 2 2 Deoxyhypusine synthase MAD PF05557.8 EIW71107.1 - 2.1e-31 108.7 4.9 2.1e-31 108.7 3.4 3.5 2 1 1 3 3 3 1 Mitotic checkpoint protein Baculo_PEP_C PF04513.7 EIW71107.1 - 5.2e-05 23.0 14.9 0.02 14.7 0.1 5.0 3 1 0 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EIW71107.1 - 0.0027 16.9 14.5 0.036 13.2 0.5 3.0 2 1 1 3 3 3 2 Reovirus sigma C capsid protein GAS PF13851.1 EIW71107.1 - 0.0067 15.6 4.1 0.0067 15.6 2.8 5.3 2 2 3 5 5 5 2 Growth-arrest specific micro-tubule binding DUF3416 PF11896.3 EIW71107.1 - 0.01 15.8 3.9 0.01 15.8 2.7 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF3416) LPP PF04728.8 EIW71107.1 - 0.011 15.5 1.5 0.38 10.5 0.1 3.8 3 1 1 4 4 4 0 Lipoprotein leucine-zipper IKKbetaNEMObind PF12179.3 EIW71107.1 - 0.028 14.2 0.1 0.1 12.4 0.1 2.0 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DUF972 PF06156.8 EIW71107.1 - 0.031 14.6 0.7 0.031 14.6 0.5 7.7 3 2 5 8 8 8 0 Protein of unknown function (DUF972) DivIC PF04977.10 EIW71107.1 - 0.035 13.5 0.6 0.035 13.5 0.4 9.1 8 2 2 10 10 10 0 Septum formation initiator HALZ PF02183.13 EIW71107.1 - 1.3 8.8 25.2 2.9 7.6 0.0 6.7 6 0 0 6 6 6 0 Homeobox associated leucine zipper NPV_P10 PF05531.7 EIW71107.1 - 8.3 6.7 13.5 19 5.6 0.7 4.8 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Pro_isomerase PF00160.16 EIW71108.1 - 3.1e-41 141.1 0.1 3.4e-41 141.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L33 PF00471.15 EIW71109.1 - 1.3e-12 47.7 0.0 1.5e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 zf-AN1 PF01428.11 EIW71110.1 - 1.1e-13 50.8 14.3 1.1e-06 28.3 3.0 2.8 2 1 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EIW71110.1 - 0.0069 16.2 4.0 0.0069 16.2 2.7 2.9 1 1 1 2 2 2 1 IBR domain Ribosomal_S27 PF01599.14 EIW71110.1 - 0.013 15.2 1.5 0.47 10.3 0.3 3.0 2 0 0 2 2 2 0 Ribosomal protein S27a DUF3446 PF11928.3 EIW71110.1 - 0.029 14.5 4.4 0.48 10.6 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) P21-Arc PF04062.9 EIW71111.1 - 5e-76 254.3 0.0 6.3e-76 254.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DHFR_1 PF00186.14 EIW71112.1 - 3.5e-35 120.9 0.0 1.1e-24 86.8 0.0 2.2 2 0 0 2 2 2 2 Dihydrofolate reductase PMT PF02366.13 EIW71113.1 - 1.3e-73 247.3 16.3 1.3e-73 247.3 11.3 2.0 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIW71113.1 - 9.6e-29 100.2 0.9 1.3e-28 99.8 0.6 1.2 1 0 0 1 1 1 1 MIR domain Histone PF00125.19 EIW71114.1 - 3.2e-30 104.0 0.3 4.8e-30 103.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW71114.1 - 1.2e-05 25.4 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EIW71114.1 - 0.017 14.3 0.8 0.018 14.2 0.5 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EIW71114.1 - 0.027 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EIW71114.1 - 0.038 13.7 0.1 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Med11 PF10280.4 EIW71115.1 - 0.0036 17.3 0.0 0.0098 15.9 0.0 1.7 1 0 0 1 1 1 1 Mediator complex protein FAM110_N PF14161.1 EIW71115.1 - 0.0091 16.2 1.3 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 Centrosome-associated N terminus PLAC9 PF15205.1 EIW71115.1 - 0.32 11.3 1.6 9.9 6.5 0.5 2.7 2 0 0 2 2 2 0 Placenta-specific protein 9 PS_Dcarbxylase PF02666.10 EIW71117.1 - 2.8e-52 176.9 0.0 4.4e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EIW71117.1 - 2.9e-30 103.9 0.0 3.4e-16 58.8 0.1 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EIW71117.1 - 0.0023 18.0 0.0 0.0063 16.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EIW71117.1 - 0.0061 15.7 0.0 0.02 14.1 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EIW71117.1 - 0.019 14.8 0.1 0.15 12.0 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain CEP76-C2 PF15627.1 EIW71117.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 CEP76 C2 domain Mito_carr PF00153.22 EIW71118.1 - 4e-50 167.4 0.5 1.7e-16 59.6 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Metallophos PF00149.23 EIW71119.1 - 5.6e-42 143.4 0.4 8.4e-42 142.8 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SRP19 PF01922.12 EIW71120.1 - 3.2e-23 82.1 0.0 8e-23 80.8 0.0 1.7 2 0 0 2 2 2 1 SRP19 protein SF3b10 PF07189.6 EIW71121.1 - 5.4e-34 115.8 0.0 6.8e-34 115.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) TIP41 PF04176.8 EIW71122.1 - 3e-44 150.4 0.0 4.2e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family Ribosomal_L4 PF00573.17 EIW71123.1 - 1.6e-45 154.8 1.0 2.4e-45 154.2 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EIW71123.1 - 8e-28 96.1 1.0 1e-26 92.5 0.1 2.5 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain EMG1 PF03587.9 EIW71124.1 - 1.5e-74 249.7 0.0 1.9e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase CRCB PF02537.10 EIW71125.1 - 1.7e-28 98.8 15.7 8.1e-19 67.6 0.3 2.7 3 1 0 3 3 3 2 CrcB-like protein Totivirus_coat PF05518.6 EIW71125.1 - 0.24 9.2 0.8 0.31 8.8 0.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein Fungal_trans PF04082.13 EIW71126.1 - 1.8e-09 36.8 0.3 3.1e-09 36.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW71126.1 - 2e-09 37.1 10.3 4.2e-09 36.1 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_I_2 PF12813.2 EIW71127.1 - 7.1e-10 38.7 0.0 1.9e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.12 EIW71127.1 - 0.017 15.3 0.0 0.11 12.8 0.0 2.4 2 1 0 2 2 2 0 XPG N-terminal domain XPG_I PF00867.13 EIW71127.1 - 0.086 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 XPG I-region Tetraspannin PF00335.15 EIW71128.1 - 0.0026 17.0 6.4 0.0088 15.3 4.5 1.8 1 1 0 1 1 1 1 Tetraspanin family Intg_mem_TP0381 PF09529.5 EIW71128.1 - 0.067 12.4 2.3 0.11 11.6 1.6 1.3 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) DUF3816 PF12822.2 EIW71128.1 - 0.07 13.0 4.6 0.032 14.1 1.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) Transket_pyr PF02779.19 EIW71128.1 - 0.45 9.9 2.2 0.3 10.5 0.2 1.5 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain RRM_5 PF13893.1 EIW71129.1 - 5e-09 35.8 0.0 9.4e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW71129.1 - 1.2e-07 31.2 0.0 4.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW71129.1 - 0.0001 22.1 0.0 0.017 15.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Adeno_E1A PF02703.9 EIW71130.1 - 0.027 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Early E1A protein Ras PF00071.17 EIW71131.1 - 1.5e-54 183.7 0.0 1.8e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW71131.1 - 6.6e-18 65.3 0.0 9.8e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW71131.1 - 3.5e-11 42.6 0.0 3.9e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIW71131.1 - 2.5e-05 24.1 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EIW71131.1 - 6.8e-05 22.1 0.0 8.8e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW71131.1 - 0.00036 20.0 0.0 0.00065 19.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EIW71131.1 - 0.036 13.2 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIW71131.1 - 0.037 13.9 0.4 0.1 12.5 0.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EIW71131.1 - 0.059 13.0 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase SRPRB PF09439.5 EIW71131.1 - 0.092 11.9 0.0 0.12 11.6 0.0 1.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Peptidase_M36 PF02128.10 EIW71132.1 - 1.6e-133 445.2 5.2 5.1e-132 440.2 3.6 2.2 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EIW71132.1 - 1.5e-10 40.3 0.1 2.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EIW71132.1 - 0.00064 19.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain PepSY PF03413.14 EIW71132.1 - 0.0092 16.6 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PTS_IIA PF02255.11 EIW71133.1 - 0.46 10.3 4.4 1.5 8.7 1.0 2.2 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit HDAC4_Gln PF12203.3 EIW71133.1 - 4.6 7.2 12.4 1.3 9.0 6.1 1.9 2 1 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 bZIP_2 PF07716.10 EIW71134.1 - 5.9e-08 32.4 17.2 2.6e-07 30.3 12.0 1.9 1 1 0 1 1 1 1 Basic region leucine zipper TSC22 PF01166.13 EIW71134.1 - 0.0012 18.7 0.9 0.0024 17.8 0.6 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_1 PF00170.16 EIW71134.1 - 0.002 18.0 15.8 0.0061 16.5 11.0 1.8 1 1 0 1 1 1 1 bZIP transcription factor DivIC PF04977.10 EIW71134.1 - 0.11 11.9 4.3 0.23 10.9 3.0 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.12 EIW71134.1 - 0.47 10.7 9.6 0.91 9.8 6.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Ribosomal_L14e PF01929.12 EIW71135.1 - 6.8e-27 93.6 0.0 1e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EIW71135.1 - 3.1e-06 26.6 0.2 5e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 KOW motif rRNA_proc-arch PF13234.1 EIW71135.1 - 0.078 12.1 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 rRNA-processing arch domain CH PF00307.26 EIW71136.1 - 1.7e-68 227.5 0.0 4.4e-19 68.5 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EIW71136.1 - 3.8e-08 32.8 0.0 2.4 7.8 0.0 4.4 4 0 0 4 4 4 4 CAMSAP CH domain EF-hand_7 PF13499.1 EIW71136.1 - 0.011 15.7 0.2 0.04 14.0 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain pair Pkinase PF00069.20 EIW71137.1 - 1.5e-64 217.6 0.0 2.5e-64 216.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71137.1 - 1.6e-46 158.5 0.0 2.6e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW71137.1 - 2.7e-10 39.7 0.0 5.4e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PRKCSH PF07915.8 EIW71138.1 - 6e-15 55.8 1.2 2.8e-14 53.6 0.8 2.1 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EIW71138.1 - 1.7e-05 24.3 0.2 0.0014 18.0 0.1 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein GLE1 PF07817.8 EIW71139.1 - 1.7e-44 151.6 3.5 3e-44 150.9 0.0 2.2 2 0 0 2 2 2 1 GLE1-like protein Borrelia_P83 PF05262.6 EIW71139.1 - 0.0022 16.3 18.6 0.0034 15.7 12.9 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein AAA_13 PF13166.1 EIW71139.1 - 3.8 5.8 18.0 11 4.3 12.5 1.7 2 0 0 2 2 2 0 AAA domain Adeno_E3_14_5 PF04834.7 EIW71140.1 - 1.4 9.4 4.3 2.6 8.5 0.1 3.0 3 0 0 3 3 3 0 Early E3 14.5 kDa protein 4HBT PF03061.17 EIW71141.1 - 3.7e-08 33.3 0.1 5.8e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DENN PF02141.16 EIW71142.1 - 1.5e-21 76.9 0.0 3.3e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain GAS PF13851.1 EIW71142.1 - 0.0014 17.8 12.8 0.0024 17.0 8.9 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 EIW71142.1 - 0.0032 15.2 13.3 0.0044 14.8 9.2 1.1 1 0 0 1 1 1 1 Myosin tail AAA_13 PF13166.1 EIW71142.1 - 0.018 13.5 2.4 0.026 13.0 1.6 1.1 1 0 0 1 1 1 0 AAA domain OmpH PF03938.9 EIW71142.1 - 0.026 14.4 8.0 0.042 13.7 5.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CAF-1_p150 PF11600.3 EIW71142.1 - 0.14 11.4 9.2 0.38 10.1 6.4 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4600 PF15372.1 EIW71142.1 - 0.2 11.8 10.8 0.46 10.7 7.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DUF342 PF03961.8 EIW71142.1 - 0.32 9.3 2.2 0.52 8.6 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EIW71142.1 - 0.37 10.3 7.9 0.66 9.5 5.5 1.3 1 0 0 1 1 1 0 IncA protein SGL PF08450.7 EIW71143.1 - 5.9e-19 68.4 0.2 1.3e-18 67.3 0.2 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EIW71143.1 - 2.1e-06 27.6 0.0 9.6e-06 25.5 0.0 2.0 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 EIW71143.1 - 3.4e-05 23.7 0.1 0.00037 20.4 0.0 2.4 1 1 1 2 2 2 1 Arylesterase RPEL PF02755.10 EIW71144.1 - 0.14 11.4 0.1 0.14 11.4 0.1 2.1 3 0 0 3 3 3 0 RPEL repeat Ras PF00071.17 EIW71145.1 - 1.3e-48 164.4 0.0 1.8e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW71145.1 - 1.6e-16 60.8 0.1 4.1e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW71145.1 - 0.00048 19.4 0.0 0.00087 18.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIW71145.1 - 0.0047 16.8 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW71145.1 - 0.045 13.0 0.0 0.59 9.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF3602 PF12223.3 EIW71146.1 - 5.3e-23 81.1 32.2 1.1e-05 25.7 0.4 5.3 2 1 3 5 5 5 5 Protein of unknown function (DUF3602) Ammonium_transp PF00909.16 EIW71147.1 - 4.3e-112 374.4 34.1 4.9e-112 374.3 23.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Corona_M PF01635.13 EIW71147.1 - 0.095 11.6 0.2 0.095 11.6 0.1 2.0 3 0 0 3 3 3 0 Coronavirus M matrix/glycoprotein Mito_carr PF00153.22 EIW71149.1 - 6.4e-58 192.4 0.7 1.3e-22 79.2 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18ae PF01775.12 EIW71150.1 - 3.8e-57 191.5 1.2 4.9e-57 191.2 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain WEMBL PF05701.6 EIW71151.1 - 0.024 13.1 29.4 0.039 12.4 20.4 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF724 PF05266.9 EIW71151.1 - 0.76 9.3 29.2 0.38 10.3 7.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) AAA_13 PF13166.1 EIW71151.1 - 0.87 7.9 21.8 1.3 7.4 15.1 1.1 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 EIW71151.1 - 1.2 8.2 34.3 0.38 9.9 7.4 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EIW71151.1 - 1.4 8.7 37.8 12 5.7 16.2 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 EIW71151.1 - 2.1 8.2 6.6 14 5.6 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 EIW71151.1 - 2.2 6.0 22.6 0.076 10.8 6.6 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 EIW71151.1 - 4 6.0 31.9 0.3 9.7 10.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 EIW71151.1 - 8.6 5.9 39.0 4.5 6.8 10.5 2.4 1 1 1 2 2 2 0 IncA protein 7tm_1 PF00001.16 EIW71152.1 - 3.2e-05 23.2 0.5 0.00021 20.5 0.0 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 EIW71152.1 - 0.00026 20.6 8.9 0.00026 20.6 6.2 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 NUDIX PF00293.23 EIW71154.1 - 1.3e-14 54.0 0.0 1.8e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain SNF2_N PF00176.18 EIW71155.1 - 1.2e-66 224.5 0.1 2.8e-65 220.0 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW71155.1 - 7.1e-13 48.2 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EIW71155.1 - 0.0052 16.4 5.9 0.016 14.8 4.3 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW71155.1 - 0.21 11.2 2.8 0.49 10.0 1.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DCA16 PF15349.1 EIW71156.1 - 0.031 13.6 0.3 0.1 11.9 0.1 1.8 2 0 0 2 2 2 0 DDB1- and CUL4-associated factor 16 Pyridox_oxase_2 PF12766.2 EIW71157.1 - 2.4e-20 72.7 0.0 3.6e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EIW71157.1 - 0.0041 17.0 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Thymidylat_synt PF00303.14 EIW71159.1 - 1.6e-106 355.2 0.0 1.8e-106 355.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase SIN1 PF05422.7 EIW71160.1 - 3.7e-30 104.9 0.0 3.3e-26 91.8 0.0 2.2 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) Herpes_ICP4_N PF03584.10 EIW71160.1 - 0.1 12.1 0.2 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region WD40 PF00400.27 EIW71161.1 - 9.8e-26 88.6 4.7 3.4e-07 29.9 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat SDA1 PF05285.7 EIW71161.1 - 1.9 7.7 13.1 2.8 7.1 9.1 1.2 1 0 0 1 1 1 0 SDA1 ArfGap PF01412.13 EIW71162.1 - 1.4e-28 99.0 0.0 2.7e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 EIW71162.1 - 1.8e-13 50.5 0.0 3.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EIW71162.1 - 0.00011 22.2 0.1 0.00054 20.1 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Polysacc_synt_4 PF04669.8 EIW71163.1 - 2.4e-22 79.2 0.7 1.6e-21 76.5 0.5 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Prp19_bind PF06991.6 EIW71164.1 - 2.3e-55 187.8 36.0 7.4e-55 186.1 25.0 1.8 1 1 0 1 1 1 1 Splicing factor, Prp19-binding domain PPR_2 PF13041.1 EIW71165.1 - 7.9e-22 76.9 2.3 3.5e-08 33.2 0.0 6.5 3 1 3 6 6 6 5 PPR repeat family PPR_3 PF13812.1 EIW71165.1 - 2.6e-17 61.5 2.0 2.3e-06 27.4 0.0 7.1 7 0 0 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.15 EIW71165.1 - 9.4e-12 44.0 2.3 0.0065 16.3 0.0 6.3 6 1 0 6 6 6 3 PPR repeat PPR_1 PF12854.2 EIW71165.1 - 1.1e-08 34.4 2.7 9.7e-06 24.9 0.0 4.7 5 1 0 5 5 5 1 PPR repeat AMP-binding PF00501.23 EIW71166.1 - 1.7e-79 267.2 0.0 2.2e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SIR2_2 PF13289.1 EIW71166.1 - 0.11 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 SIR2-like domain DUF4315 PF14193.1 EIW71167.1 - 0.031 14.1 0.0 0.097 12.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) SPRY PF00622.23 EIW71170.1 - 1.9e-16 60.2 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Gemini_mov PF01708.11 EIW71170.1 - 0.035 13.6 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 Geminivirus putative movement protein TMEM154 PF15102.1 EIW71170.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.11 EIW71170.1 - 0.19 9.9 0.1 0.59 8.3 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E NCA2 PF08637.5 EIW71171.1 - 2.1e-79 266.4 0.0 2.8e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 DNA_primase_lrg PF04104.9 EIW71172.1 - 1.5e-87 293.1 0.0 2e-87 292.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Methyltransf_33 PF10017.4 EIW71173.1 - 8e-24 83.9 0.0 1.7e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EIW71173.1 - 3.3e-22 79.0 0.1 7.3e-21 74.6 0.0 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EIW71173.1 - 2.4e-08 34.3 3.9 6.1e-08 33.0 2.7 1.7 1 0 0 1 1 1 1 DinB superfamily Erp_C PF06780.6 EIW71173.1 - 0.21 11.4 0.0 0.47 10.2 0.0 1.5 1 0 0 1 1 1 0 Erp protein C-terminus Cauli_VI PF01693.11 EIW71174.1 - 5.9e-11 42.2 0.1 1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF1996 PF09362.5 EIW71175.1 - 6.7e-50 169.9 1.2 8.9e-50 169.5 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AAA_16 PF13191.1 EIW71176.1 - 3.8e-11 43.3 0.0 8.1e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EIW71176.1 - 2.3e-09 37.5 0.0 4.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW71176.1 - 1.6e-07 31.5 0.0 4.7e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIW71176.1 - 3.2e-05 23.5 0.0 6.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW71176.1 - 6.9e-05 22.5 0.0 0.00017 21.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EIW71176.1 - 0.00025 20.5 0.0 0.00051 19.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EIW71176.1 - 0.00083 20.1 0.0 0.0015 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIW71176.1 - 0.00085 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EIW71176.1 - 0.0013 18.4 0.5 0.013 15.1 0.3 2.3 1 1 0 1 1 1 1 NACHT domain TIP49 PF06068.8 EIW71176.1 - 0.0025 16.5 0.0 0.024 13.3 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus NTPase_1 PF03266.10 EIW71176.1 - 0.006 16.2 0.1 0.015 14.9 0.1 1.7 1 1 0 1 1 1 1 NTPase PIF1 PF05970.9 EIW71176.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_28 PF13521.1 EIW71176.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIW71176.1 - 0.032 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase ArgK PF03308.11 EIW71176.1 - 0.033 12.9 0.1 0.085 11.6 0.0 1.6 2 0 0 2 2 2 0 ArgK protein TrwB_AAD_bind PF10412.4 EIW71176.1 - 0.035 12.7 0.0 0.061 11.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 EIW71176.1 - 0.038 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EIW71176.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIW71176.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EIW71176.1 - 0.091 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MobB PF03205.9 EIW71176.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EIW71176.1 - 0.096 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cdc6_C PF09079.6 EIW71176.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 CDC6, C terminal RNA_helicase PF00910.17 EIW71176.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AFG1_ATPase PF03969.11 EIW71176.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Rad17 PF03215.10 EIW71176.1 - 0.2 10.3 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DEAD PF00270.24 EIW71177.1 - 3.1e-35 121.1 0.0 6.2e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EIW71177.1 - 1.6e-17 62.8 0.3 3.1e-17 61.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EIW71177.1 - 3.3e-16 58.9 0.0 7.4e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW71177.1 - 0.0026 17.6 1.2 0.053 13.3 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Mito_carr PF00153.22 EIW71178.1 - 3.6e-67 222.1 0.1 7.5e-22 76.8 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2715 PF10895.3 EIW71179.1 - 0.00046 19.7 19.2 0.15 11.5 1.1 3.6 1 1 2 3 3 3 3 Protein of unknown function (DUF2715) Corona_NS4 PF03905.8 EIW71179.1 - 0.12 12.1 33.7 0.31 10.8 0.5 6.4 4 2 2 6 6 6 0 Coronavirus non-structural protein NS4 DUF3996 PF13161.1 EIW71179.1 - 0.49 10.0 16.4 12 5.5 11.4 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3996) FAA_hydrolase PF01557.13 EIW71181.1 - 4.5e-55 186.4 0.0 5.8e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.12 EIW71181.1 - 0.046 13.2 0.8 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 KH domain CHCH PF06747.8 EIW71182.1 - 1.7e-05 24.6 5.3 2.3e-05 24.2 3.6 1.2 1 0 0 1 1 1 1 CHCH domain Arteri_env PF01606.11 EIW71182.1 - 0.078 12.6 0.0 0.095 12.3 0.0 1.0 1 0 0 1 1 1 0 Arterivirus envelope protein RNA_pol_Rbc25 PF08292.7 EIW71184.1 - 7.3e-30 103.6 0.2 1.5e-29 102.6 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EIW71184.1 - 7.8e-12 45.1 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUDIX PF00293.23 EIW71185.1 - 1.7e-12 47.0 0.0 2.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Phosphonate-bd PF12974.2 EIW71187.1 - 2.9e-09 36.6 0.0 3.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 EIW71187.1 - 0.00051 19.6 0.0 0.00084 18.9 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SPDY PF03771.11 EIW71187.1 - 0.015 14.7 0.1 0.041 13.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF317) DUF4026 PF13218.1 EIW71187.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) SBP_bac_3 PF00497.15 EIW71187.1 - 0.034 13.4 0.0 0.075 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 CFEM PF05730.6 EIW71188.1 - 1.5e-09 37.5 16.1 2.5e-09 36.8 11.2 1.4 1 0 0 1 1 1 1 CFEM domain DUF4006 PF13179.1 EIW71188.1 - 0.16 11.5 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Glycophorin_A PF01102.13 EIW71188.1 - 3.1 7.5 6.7 0.73 9.6 1.7 2.2 2 1 0 2 2 2 0 Glycophorin A Ribosomal_L23 PF00276.15 EIW71189.1 - 4.7e-11 42.4 0.0 5.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 BIR PF00653.16 EIW71190.1 - 2e-33 114.6 3.2 2.4e-17 63.1 0.7 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Mg_trans_NIPA PF05653.9 EIW71191.1 - 8.8e-105 349.9 16.8 1.6e-104 349.0 11.7 1.4 1 1 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EIW71191.1 - 5.7e-07 29.7 1.3 5.7e-07 29.7 0.9 3.7 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EIW71191.1 - 0.00031 20.7 5.9 0.00031 20.7 4.1 3.6 3 1 1 4 4 4 1 EamA-like transporter family DUF2937 PF11157.3 EIW71191.1 - 0.024 13.9 0.2 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Rax2 PF12768.2 EIW71191.1 - 0.035 13.3 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4131 PF13567.1 EIW71191.1 - 0.86 8.9 5.3 6.1 6.2 0.1 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) zf-CCHC PF00098.18 EIW71194.1 - 0.0015 18.3 1.9 0.0026 17.6 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW71194.1 - 0.034 13.8 0.1 0.081 12.6 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIW71195.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW71195.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW71195.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Pap_E4 PF02711.9 EIW71196.1 - 0.73 10.6 11.2 0.096 13.5 2.5 2.4 2 0 0 2 2 2 0 E4 protein SR-25 PF10500.4 EIW71196.1 - 2 7.8 23.7 3 7.2 16.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SOG2 PF10428.4 EIW71196.1 - 2.3 6.7 6.3 2.6 6.5 4.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DTHCT PF08070.6 EIW71196.1 - 2.6 8.7 9.6 11 6.7 0.0 2.1 2 0 0 2 2 2 0 DTHCT (NUC029) region Peptidase_S21 PF00716.12 EIW71196.1 - 3.1 7.0 11.1 3.8 6.7 7.7 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) DUF566 PF04484.7 EIW71196.1 - 3.7 6.9 13.0 4.3 6.7 9.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) FAM117 PF15388.1 EIW71196.1 - 7.2 5.7 17.2 8.8 5.4 12.0 1.1 1 0 0 1 1 1 0 Protein Family FAM117 RVT_1 PF00078.22 EIW71197.1 - 5.4e-22 78.2 0.1 2e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIW71197.1 - 1.3e-18 67.2 0.0 4.1e-18 65.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIW71197.1 - 3.3e-08 33.0 0.1 1e-07 31.5 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3818 PF12825.2 EIW71197.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Med12 PF09497.5 EIW71199.1 - 1.9e-22 78.9 0.0 4.5e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 AAA_5 PF07728.9 EIW71201.1 - 6.2e-103 340.2 0.1 2.5e-20 72.6 0.0 10.1 9 1 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIW71201.1 - 2.1e-25 88.8 0.0 4.5e-09 36.0 0.0 6.6 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EIW71201.1 - 1e-18 67.8 0.1 0.0015 18.7 0.0 6.0 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW71201.1 - 1.6e-16 60.6 5.6 0.047 13.8 0.0 9.2 9 0 0 9 9 8 4 AAA domain Sigma54_activat PF00158.21 EIW71201.1 - 8.1e-16 57.9 0.0 0.0092 15.4 0.0 5.3 5 0 0 5 5 5 4 Sigma-54 interaction domain AAA_16 PF13191.1 EIW71201.1 - 2.3e-15 57.0 15.0 0.00091 19.2 0.0 8.5 8 0 0 8 8 7 3 AAA ATPase domain AAA_18 PF13238.1 EIW71201.1 - 7.6e-15 55.3 0.5 0.1 12.8 0.0 6.6 6 0 0 6 6 5 4 AAA domain Sigma54_activ_2 PF14532.1 EIW71201.1 - 3.1e-14 53.1 6.1 0.00041 20.3 0.0 7.3 7 0 0 7 7 6 3 Sigma-54 interaction domain AAA_17 PF13207.1 EIW71201.1 - 1.1e-13 52.1 4.6 0.057 14.2 0.0 7.0 7 0 0 7 7 5 3 AAA domain UPF0079 PF02367.12 EIW71201.1 - 2.6e-10 39.9 1.9 0.32 10.6 0.0 5.7 5 0 0 5 5 5 2 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 EIW71201.1 - 4.1e-10 39.6 0.0 0.0059 16.4 0.0 5.5 6 0 0 6 6 5 2 AAA domain AAA_33 PF13671.1 EIW71201.1 - 1.5e-09 37.8 0.3 0.33 10.8 0.0 6.7 6 1 0 6 6 6 2 AAA domain T2SE PF00437.15 EIW71201.1 - 2.1e-09 36.6 1.5 0.09 11.6 0.2 4.8 5 0 0 5 5 5 3 Type II/IV secretion system protein Zeta_toxin PF06414.7 EIW71201.1 - 5.6e-09 35.3 0.5 0.28 10.2 0.0 5.3 6 0 0 6 6 4 2 Zeta toxin AAA_19 PF13245.1 EIW71201.1 - 6.3e-09 35.4 1.8 0.13 11.9 0.0 4.9 4 0 0 4 4 4 2 Part of AAA domain Miro PF08477.8 EIW71201.1 - 4.9e-08 33.4 0.3 2.2 8.7 0.0 5.9 5 0 0 5 5 5 1 Miro-like protein AAA_29 PF13555.1 EIW71201.1 - 1.2e-07 31.0 0.4 0.45 10.0 0.0 5.0 5 0 0 5 5 5 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 EIW71201.1 - 5.1e-07 29.8 0.1 3.9 7.6 0.0 5.2 4 0 0 4 4 4 1 RNA helicase ABC_tran PF00005.22 EIW71201.1 - 9.5e-07 29.1 12.5 0.06 13.6 0.0 6.6 6 1 0 6 6 5 2 ABC transporter NACHT PF05729.7 EIW71201.1 - 1.1e-06 28.4 1.0 1.7 8.2 0.0 5.9 5 0 0 5 5 5 1 NACHT domain Mg_chelatase PF01078.16 EIW71201.1 - 1.1e-06 27.9 0.1 8.2 5.5 0.0 6.6 8 0 0 8 8 7 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EIW71201.1 - 7.5e-06 25.0 0.1 1.7 7.5 0.0 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF815) MobB PF03205.9 EIW71201.1 - 9.6e-06 25.3 0.4 1.8 8.3 0.0 4.5 4 0 0 4 4 4 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EIW71201.1 - 3.4e-05 23.3 0.1 1.2 8.5 0.0 4.5 4 0 0 4 4 4 1 IstB-like ATP binding protein RuvB_N PF05496.7 EIW71201.1 - 5.5e-05 22.3 0.1 5.3 6.0 0.0 5.0 6 0 0 6 6 5 0 Holliday junction DNA helicase ruvB N-terminus PduV-EutP PF10662.4 EIW71201.1 - 5.7e-05 22.6 0.4 3.8 6.9 0.0 4.3 5 0 0 5 5 3 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EIW71201.1 - 0.00011 22.2 4.3 1.9 8.4 0.0 5.6 6 0 0 6 6 5 1 AAA domain DUF258 PF03193.11 EIW71201.1 - 0.00013 21.2 0.3 1.1 8.4 0.0 4.4 5 0 0 5 5 5 1 Protein of unknown function, DUF258 SRP54 PF00448.17 EIW71201.1 - 0.00035 20.0 1.2 5.1 6.4 0.1 3.9 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EIW71201.1 - 0.00058 20.2 16.3 0.024 14.9 0.0 5.9 5 0 0 5 5 4 1 AAA domain AAA_6 PF12774.2 EIW71201.1 - 0.00091 18.8 0.0 8.4 5.8 0.0 4.9 5 0 0 5 5 5 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_25 PF13481.1 EIW71201.1 - 0.0011 18.4 1.3 10 5.4 0.0 4.5 4 0 0 4 4 3 0 AAA domain IPT PF01745.11 EIW71201.1 - 0.014 14.5 0.5 8.3 5.5 0.0 3.1 3 0 0 3 3 3 0 Isopentenyl transferase NTPase_1 PF03266.10 EIW71201.1 - 0.032 13.9 1.8 26 4.4 0.2 4.0 3 0 0 3 3 3 0 NTPase AAA_7 PF12775.2 EIW71201.1 - 0.21 10.6 0.0 6.7 5.7 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region D3 ATP_bind_1 PF03029.12 EIW71201.1 - 0.22 11.0 4.9 19 4.6 0.0 4.1 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Bunya_G2 PF03563.8 EIW71201.1 - 3.2 6.5 0.1 5.7 5.7 0.1 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 RVT_1 PF00078.22 EIW71203.1 - 7.1e-22 77.8 0.0 1.9e-21 76.4 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIW71203.1 - 1.1e-18 67.5 0.1 4.1e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EIW71203.1 - 1e-07 31.5 0.1 1e-07 31.5 0.1 2.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3818 PF12825.2 EIW71203.1 - 0.1 11.2 0.0 0.19 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) zf-CCHC PF00098.18 EIW71204.1 - 0.0009 19.0 1.9 0.0015 18.3 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW71204.1 - 0.025 14.3 0.2 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle MULE PF10551.4 EIW71205.1 - 1.5e-14 53.8 1.6 4.4e-11 42.8 0.2 3.7 2 1 0 2 2 2 1 MULE transposase domain rve PF00665.21 EIW71205.1 - 0.072 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Ribophorin_I PF04597.9 EIW71206.1 - 1.6e-118 395.9 0.0 1.9e-118 395.7 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Sld5 PF05916.6 EIW71207.1 - 9.9e-07 29.0 0.0 1.3e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sugar_tr PF00083.19 EIW71208.1 - 2.5e-33 115.3 25.6 4.5e-33 114.5 17.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW71208.1 - 2.6e-30 105.3 35.5 2.6e-30 105.3 24.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily NAD_binding_10 PF13460.1 EIW71209.1 - 1.8e-10 41.1 0.0 2.3e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW71209.1 - 3.1e-05 23.5 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW71209.1 - 0.00082 18.6 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EIW71209.1 - 0.022 13.6 0.0 3 6.6 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIW71209.1 - 0.061 12.0 0.0 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 EIW71209.1 - 0.089 12.5 0.4 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KH_1 PF00013.24 EIW71210.1 - 3.8e-07 29.6 0.0 3.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EIW71210.1 - 3.2e-05 23.4 0.5 0.0051 16.4 0.0 2.4 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.14 EIW71210.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Trp repressor protein Helitron_like_N PF14214.1 EIW71217.1 - 4e-61 205.9 0.0 6.1e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Macin PF14865.1 EIW71217.1 - 0.019 15.0 0.7 0.036 14.1 0.5 1.3 1 0 0 1 1 1 0 Macin DUF2587 PF10759.4 EIW71218.1 - 0.043 13.2 0.1 0.11 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Mito_carr PF00153.22 EIW71219.1 - 2.5e-35 120.0 0.1 6.9e-14 51.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.20 EIW71221.1 - 2.2e-19 70.0 2.4 1e-18 67.8 1.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW71221.1 - 6.1e-09 36.0 0.2 3e-08 33.7 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW71221.1 - 8.1e-06 25.6 0.8 0.001 18.8 0.1 2.1 2 0 0 2 2 2 2 KR domain Acyl-CoA_dh_1 PF00441.19 EIW71222.1 - 5.2e-31 107.7 1.3 7.3e-31 107.3 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EIW71222.1 - 3.8e-15 56.3 0.5 3.8e-15 56.3 0.4 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIW71222.1 - 2.4e-10 40.9 0.0 5.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EIW71222.1 - 7.2e-08 31.8 0.1 1.7e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain UPF0489 PF12640.2 EIW71222.1 - 0.095 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Cyt-b5 PF00173.23 EIW71223.1 - 9.3e-17 60.6 0.0 2.2e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EIW71223.1 - 1e-13 51.3 22.0 1e-13 51.3 15.2 1.8 1 1 1 2 2 2 1 Fatty acid desaturase UQ_con PF00179.21 EIW71224.1 - 3e-38 130.4 0.0 3.7e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW71224.1 - 0.0016 18.1 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIW71224.1 - 0.029 14.2 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Pcc1 PF09341.5 EIW71225.1 - 1.2e-21 76.4 1.3 1.7e-21 76.0 0.9 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 AAA PF00004.24 EIW71226.1 - 2.4e-44 150.7 0.0 4.5e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIW71226.1 - 7.5e-07 29.2 0.0 2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIW71226.1 - 9e-07 28.7 0.0 5.2e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIW71226.1 - 2e-06 27.9 0.3 0.00019 21.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW71226.1 - 2.9e-06 27.3 0.1 9.2e-06 25.7 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_19 PF13245.1 EIW71226.1 - 6.1e-05 22.7 0.1 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EIW71226.1 - 0.0001 23.1 0.0 0.00024 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIW71226.1 - 0.00012 21.2 0.0 0.00025 20.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EIW71226.1 - 0.00031 20.2 0.0 0.00073 18.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EIW71226.1 - 0.001 17.8 0.0 0.0021 16.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EIW71226.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EIW71226.1 - 0.0013 18.0 0.0 0.069 12.3 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.1 EIW71226.1 - 0.002 18.0 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW71226.1 - 0.0021 18.3 0.0 0.0096 16.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EIW71226.1 - 0.003 16.6 0.0 0.0057 15.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EIW71226.1 - 0.0034 17.3 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EIW71226.1 - 0.0048 16.4 0.0 0.0089 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EIW71226.1 - 0.0065 15.6 0.1 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EIW71226.1 - 0.0074 15.4 0.0 0.033 13.2 0.0 1.9 2 0 0 2 2 2 1 KaiC DUF2072 PF09845.4 EIW71226.1 - 0.0079 16.1 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_25 PF13481.1 EIW71226.1 - 0.0091 15.4 0.1 0.099 12.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 EIW71226.1 - 0.017 14.7 0.0 0.54 9.8 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 EIW71226.1 - 0.019 14.4 0.1 0.097 12.1 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EIW71226.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW71226.1 - 0.023 13.6 0.0 0.041 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EIW71226.1 - 0.038 14.1 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EIW71226.1 - 0.04 13.9 0.0 0.18 11.8 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EIW71226.1 - 0.047 12.5 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EIW71226.1 - 0.091 11.5 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DivIC PF04977.10 EIW71226.1 - 1.4 8.4 4.8 3.5 7.1 3.3 1.6 1 0 0 1 1 1 0 Septum formation initiator JTB PF05439.7 EIW71227.1 - 0.00053 19.7 0.9 0.0018 18.0 0.6 1.8 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) WD40 PF00400.27 EIW71228.1 - 2.7e-26 90.4 20.7 1.2e-05 24.9 0.4 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat IKI3 PF04762.7 EIW71228.1 - 0.0013 16.6 0.1 0.003 15.4 0.0 1.6 2 0 0 2 2 2 1 IKI3 family PD40 PF07676.7 EIW71228.1 - 0.12 12.0 4.5 5.4 6.7 0.1 4.3 4 1 0 4 4 4 0 WD40-like Beta Propeller Repeat Glyco_tran_WbsX PF14307.1 EIW71228.1 - 0.13 11.4 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase WbsX DUF3639 PF12341.3 EIW71228.1 - 9.2 6.3 12.2 5.2 7.1 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3639) MgtE PF01769.11 EIW71229.1 - 7.6e-24 84.5 10.4 2.1e-07 31.2 0.1 3.7 4 0 0 4 4 4 3 Divalent cation transporter HECT PF00632.20 EIW71232.1 - 1.9e-93 313.1 0.0 2.5e-93 312.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EIW71232.1 - 0.0031 17.0 0.2 0.012 15.1 0.2 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif DCP1 PF06058.8 EIW71233.1 - 2e-17 63.3 0.0 2.5e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family NUDIX PF00293.23 EIW71234.1 - 4.1e-10 39.4 0.0 5.1e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Adeno_E3_CR2 PF02439.10 EIW71237.1 - 0.18 11.3 0.0 0.45 10.0 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase PF00069.20 EIW71239.1 - 1.3e-72 244.0 0.0 1.6e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71239.1 - 9.6e-34 116.6 0.0 1.3e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIW71239.1 - 2.9e-10 40.5 0.8 8.9e-10 38.9 0.5 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EIW71239.1 - 0.0005 19.1 0.0 0.00081 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW71239.1 - 0.017 14.1 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW71239.1 - 0.035 13.8 0.1 0.096 12.4 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW71239.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SAP18 PF06487.7 EIW71240.1 - 4.2e-20 71.7 0.0 6.1e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Mmp37 PF09139.6 EIW71241.1 - 1.8e-99 332.8 0.0 2.5e-99 332.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 UNC-50 PF05216.8 EIW71242.1 - 1.1e-76 257.0 13.5 1.3e-76 256.8 9.3 1.0 1 0 0 1 1 1 1 UNC-50 family UPF0233 PF06781.7 EIW71242.1 - 0.32 10.6 7.2 0.67 9.6 0.1 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0233) RRM_1 PF00076.17 EIW71243.1 - 9.3e-09 34.8 0.0 0.0039 16.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW71243.1 - 0.00019 21.3 0.0 0.89 9.5 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW71243.1 - 0.16 11.8 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim17 PF02466.14 EIW71244.1 - 1.7e-12 47.5 10.3 2.4e-12 47.0 7.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 EIW71244.1 - 0.59 10.2 12.2 0.046 13.8 4.7 1.9 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 EIW71244.1 - 4.8 6.9 16.4 2.6 7.7 3.5 3.1 3 0 0 3 3 3 0 Glycine zipper UQ_con PF00179.21 EIW71245.1 - 1.1e-35 122.0 0.1 1.5e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ras PF00071.17 EIW71246.1 - 2.5e-42 143.9 0.0 2.8e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW71246.1 - 1.5e-20 73.8 0.0 1.7e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW71246.1 - 6.1e-14 51.6 0.0 6.9e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW71246.1 - 2.8e-07 29.9 0.0 3.3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIW71246.1 - 1.1e-05 25.3 0.0 1.4e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EIW71246.1 - 1.3e-05 24.4 0.0 2e-05 23.9 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EIW71246.1 - 0.002 18.1 0.2 0.0079 16.1 0.1 1.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EIW71246.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIW71246.1 - 0.018 14.7 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.9 EIW71246.1 - 0.021 14.5 0.1 0.025 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EIW71246.1 - 0.025 14.8 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EIW71246.1 - 0.038 13.1 0.4 0.062 12.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EIW71246.1 - 0.067 12.7 0.2 0.074 12.6 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIW71246.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW71246.1 - 0.14 12.3 0.2 2.2 8.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase PFK PF00365.15 EIW71247.1 - 6.6e-158 524.0 0.1 4.1e-90 301.5 0.0 3.5 3 1 0 3 3 3 3 Phosphofructokinase FAM216B PF15107.1 EIW71247.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 FAM216B protein family Ada3 PF10198.4 EIW71248.1 - 3e-30 104.6 0.9 9.6e-30 103.0 0.6 1.8 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 EXS PF03124.9 EIW71249.1 - 1.7e-93 313.3 0.0 2.2e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 EXS family Nup54 PF13874.1 EIW71250.1 - 6.2e-25 87.4 1.8 1.5e-24 86.2 1.2 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EIW71250.1 - 1.1 9.5 98.9 0.91 9.7 22.4 3.4 1 1 1 2 2 2 0 Nucleoporin FG repeat region TPR_12 PF13424.1 EIW71251.1 - 0.0028 17.5 2.3 0.079 12.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIW71251.1 - 0.015 14.9 0.2 0.31 10.7 0.1 2.6 2 0 0 2 2 2 0 TPR repeat Ubiq_cyt_C_chap PF03981.7 EIW71251.1 - 0.11 12.2 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone MIT PF04212.13 EIW71251.1 - 0.35 10.7 2.5 0.86 9.5 0.3 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 EIW71252.1 - 3.4e-28 97.0 8.8 2.2e-06 27.1 0.0 6.6 5 1 1 6 6 6 5 TPR repeat TPR_1 PF00515.23 EIW71252.1 - 1.2e-17 62.6 13.2 0.019 14.5 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 EIW71252.1 - 3.7e-17 60.8 16.8 0.026 14.4 0.0 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 EIW71252.1 - 4.9e-17 61.6 9.6 5.4e-05 23.0 0.3 6.7 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW71252.1 - 7.6e-17 61.5 12.0 1.3e-06 28.9 0.7 5.4 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIW71252.1 - 2.4e-15 56.5 9.5 0.00088 19.5 1.2 6.4 5 1 2 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 EIW71252.1 - 2.8e-13 48.5 2.4 0.085 12.6 0.0 8.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW71252.1 - 9.8e-13 47.2 0.5 0.0049 16.9 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIW71252.1 - 1.2e-11 44.1 17.9 0.074 13.7 0.0 8.0 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 EIW71252.1 - 3.2e-09 36.6 6.6 0.7 10.4 0.8 7.2 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW71252.1 - 5.2e-09 36.1 2.1 0.0015 18.6 0.1 5.1 4 2 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIW71252.1 - 7.6e-08 32.0 10.3 0.00021 21.0 0.5 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW71252.1 - 5.5e-07 28.9 9.2 0.9 9.4 0.4 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 EIW71252.1 - 5.9e-06 26.3 3.8 0.13 12.3 0.0 4.9 4 1 2 6 6 5 1 Tetratricopeptide repeat Clathrin PF00637.15 EIW71252.1 - 0.016 14.7 0.2 5.1 6.6 0.1 3.1 3 0 0 3 3 3 0 Region in Clathrin and VPS PPR PF01535.15 EIW71252.1 - 0.044 13.7 0.2 15 5.8 0.1 4.1 4 0 0 4 4 4 0 PPR repeat RabGAP-TBC PF00566.13 EIW71253.1 - 1e-31 110.1 0.1 8.6e-30 103.8 0.1 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EIW71253.1 - 1.1e-05 25.4 0.7 4.7e-05 23.4 0.5 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EIW71253.1 - 6.4e-05 22.5 0.4 0.00044 19.9 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EIW71253.1 - 0.00022 20.3 0.1 0.00085 18.4 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EIW71253.1 - 0.003 17.1 0.2 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EIW71253.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region ATE_C PF04377.10 EIW71254.1 - 2.4e-44 150.4 0.0 3.7e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EIW71254.1 - 5.4e-05 22.9 0.7 0.00011 21.9 0.5 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus adh_short PF00106.20 EIW71255.1 - 3.9e-06 26.8 0.0 5.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase TPP_enzyme_N PF02776.13 EIW71256.1 - 1.7e-32 112.2 0.0 3e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIW71256.1 - 3.3e-25 88.4 0.0 5.6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EIW71256.1 - 6.7e-14 51.7 0.0 1.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain WW PF00397.21 EIW71257.1 - 1.1e-07 31.6 1.5 2.6e-07 30.3 1.1 1.7 1 0 0 1 1 1 1 WW domain Gag_p12 PF01141.13 EIW71257.1 - 0.016 15.3 1.4 0.016 15.3 1.0 2.0 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Tetraspannin PF00335.15 EIW71258.1 - 7.9e-13 48.2 10.4 1.1e-12 47.7 7.2 1.2 1 0 0 1 1 1 1 Tetraspanin family Sec2p PF06428.6 EIW71259.1 - 2.2e-17 62.7 5.1 2.2e-17 62.7 3.5 2.3 1 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p V-SNARE PF05008.10 EIW71259.1 - 0.046 13.8 0.2 0.046 13.8 0.1 2.6 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Peptidase_S46 PF10459.4 EIW71259.1 - 7.6 4.8 11.0 11 4.2 7.6 1.1 1 0 0 1 1 1 0 Peptidase S46 Citrate_synt PF00285.16 EIW71260.1 - 2e-17 62.9 0.1 1.1e-15 57.2 0.0 2.6 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EIW71260.1 - 1.3e-15 57.2 0.0 3.1e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 EIW71260.1 - 5.5e-13 49.2 0.0 1.7e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 EIW71260.1 - 3.6e-07 29.8 0.0 1.3e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 EIW71260.1 - 1e-05 25.0 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain SURF4 PF02077.10 EIW71261.1 - 2.4e-95 318.9 7.6 2.8e-95 318.7 5.3 1.0 1 0 0 1 1 1 1 SURF4 family IBB PF01749.15 EIW71262.1 - 2.8 8.1 15.8 10 6.3 10.9 1.9 1 1 0 1 1 1 0 Importin beta binding domain FYDLN_acid PF09538.5 EIW71262.1 - 3.4 8.2 8.9 6 7.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) HEAT_2 PF13646.1 EIW71263.1 - 1e-05 25.7 1.2 1e-05 25.7 0.8 4.5 3 2 2 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EIW71263.1 - 0.027 14.9 10.8 0.38 11.3 0.2 5.3 4 1 1 5 5 5 0 HEAT-like repeat HEAT PF02985.17 EIW71263.1 - 0.28 11.3 11.8 2.3 8.5 0.1 5.7 7 0 0 7 7 7 0 HEAT repeat Piwi PF02171.12 EIW71265.1 - 5e-78 262.1 0.6 7.9e-78 261.4 0.4 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EIW71265.1 - 3.5e-14 52.2 0.1 1e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EIW71265.1 - 2.1e-11 42.9 0.1 4.7e-11 41.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Peptidase_S8 PF00082.17 EIW71266.1 - 3.7e-52 177.2 10.3 5.8e-52 176.5 7.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EIW71266.1 - 4.4e-12 46.4 0.0 8.1e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 BMC PF00936.14 EIW71266.1 - 3.6 7.3 7.6 4.6 6.9 2.3 2.5 2 0 0 2 2 2 0 BMC domain PCI PF01399.22 EIW71268.1 - 1.7e-14 54.0 0.1 5.2e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 PCI domain eIF-6 PF01912.13 EIW71269.1 - 2.3e-84 281.4 0.1 3.2e-84 280.9 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family FGGY_C PF02782.11 EIW71270.1 - 1e-42 146.0 0.2 2.7e-42 144.6 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EIW71270.1 - 1.4e-22 80.2 0.2 9.5e-19 67.6 0.0 3.1 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EIW71270.1 - 0.00015 21.1 0.6 0.45 9.7 0.1 2.5 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family UPF0075 PF03702.9 EIW71270.1 - 0.022 13.6 0.2 0.15 10.9 0.0 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0075) Asp PF00026.18 EIW71271.1 - 5.2e-72 242.7 9.2 7.3e-72 242.2 6.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW71271.1 - 1.2e-06 28.5 3.3 1.2e-06 28.5 2.3 2.5 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal bZIP_1 PF00170.16 EIW71272.1 - 2e-05 24.4 11.2 0.00071 19.4 7.7 2.4 1 1 0 1 1 1 1 bZIP transcription factor F-box-like PF12937.2 EIW71274.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like SHMT PF00464.14 EIW71275.1 - 7.4e-178 590.9 0.0 8.5e-178 590.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EIW71275.1 - 0.00042 19.5 0.0 0.00079 18.6 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EIW71275.1 - 0.046 12.6 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Topoisom_bac PF01131.15 EIW71276.1 - 1.8e-96 323.4 0.0 2.2e-96 323.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 EIW71276.1 - 9.5e-29 99.0 14.4 2.3e-14 53.0 2.2 2.7 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.17 EIW71276.1 - 1.5e-19 69.7 0.0 2.9e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-CCHC PF00098.18 EIW71276.1 - 7.1e-19 66.7 27.1 3.6e-07 29.7 3.3 3.7 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 EIW71276.1 - 6.6e-10 38.5 9.9 0.021 14.5 0.9 3.5 3 0 0 3 3 3 3 Zinc knuckle eIF3g PF12353.3 EIW71276.1 - 2e-05 24.4 3.5 1.3 8.9 0.1 3.5 3 0 0 3 3 3 3 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.1 EIW71276.1 - 0.0012 18.2 19.6 0.032 13.7 1.1 3.7 3 0 0 3 3 3 3 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.1 EIW71276.1 - 0.0049 16.3 9.3 0.07 12.6 0.1 3.7 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.1 EIW71276.1 - 0.2 11.3 14.2 3.8 7.2 0.6 3.6 3 0 0 3 3 3 0 Zinc knuckle Pantoate_transf PF02548.10 EIW71277.1 - 1.6e-91 306.0 0.0 2.4e-91 305.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Rsm22 PF09243.5 EIW71277.1 - 1.1e-42 146.0 0.0 8.6e-34 116.8 0.0 2.9 1 1 1 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 PEP_mutase PF13714.1 EIW71277.1 - 0.00012 21.3 0.0 0.00021 20.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Peptidase_S24 PF00717.18 EIW71279.1 - 6.2e-09 35.3 0.0 9.9e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like tRNA-synt_1b PF00579.20 EIW71280.1 - 4.9e-22 78.4 0.0 3.6e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) PC_rep PF01851.17 EIW71281.1 - 9.6e-27 91.6 14.0 0.00025 21.0 0.2 9.2 9 0 0 9 9 9 6 Proteasome/cyclosome repeat TPR_12 PF13424.1 EIW71281.1 - 0.02 14.8 2.3 1.5 8.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat BC10 PF06726.7 EIW71282.1 - 0.042 13.8 0.5 0.092 12.7 0.3 1.5 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 Macoilin PF09726.4 EIW71282.1 - 0.92 7.7 6.6 0.98 7.6 4.6 1.2 1 0 0 1 1 1 0 Transmembrane protein CytochromB561_N PF09786.4 EIW71282.1 - 2.1 6.7 11.7 4.1 5.7 8.1 1.5 1 0 0 1 1 1 0 Cytochrome B561, N terminal SSP160 PF06933.6 EIW71282.1 - 2.6 5.9 17.3 3.3 5.5 12.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 La PF05383.12 EIW71283.1 - 8.9e-20 70.2 0.0 1.7e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 La domain Ribosomal_S4 PF00163.14 EIW71284.1 - 5.3e-14 52.3 0.8 8e-14 51.7 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EIW71284.1 - 5.4e-11 41.7 0.0 1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 S4 domain ATG13 PF10033.4 EIW71284.1 - 0.053 12.9 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 13 AKNA PF12443.3 EIW71284.1 - 0.13 12.2 1.0 0.21 11.6 0.7 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor CopD PF05425.8 EIW71285.1 - 0.02 15.1 2.2 0.54 10.4 0.3 2.8 3 0 0 3 3 3 0 Copper resistance protein D Glycogen_syn PF05693.8 EIW71286.1 - 0 1074.9 0.0 0 1074.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EIW71286.1 - 2.8e-08 33.3 0.0 9e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EIW71286.1 - 1.1e-05 25.0 0.1 2.9e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EIW71286.1 - 0.00016 21.8 0.0 0.0005 20.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain DUF3533 PF12051.3 EIW71287.1 - 1.2e-96 323.8 18.9 1.4e-96 323.5 13.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF3671 PF12420.3 EIW71287.1 - 1.8 8.5 0.0 1.8 8.5 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function RrnaAD PF00398.15 EIW71288.1 - 1.3e-51 175.1 0.0 1.7e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EIW71288.1 - 6.4e-09 35.8 0.0 1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW71288.1 - 9.6e-05 22.9 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW71288.1 - 0.00053 19.4 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EIW71288.1 - 0.00069 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EIW71288.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW71288.1 - 0.0019 18.6 0.0 0.0035 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW71288.1 - 0.0037 17.0 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EIW71288.1 - 0.0038 16.1 0.0 0.0059 15.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_25 PF13649.1 EIW71288.1 - 0.0092 16.3 0.0 0.023 15.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Zn_ribbon_2 PF12674.2 EIW71288.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative zinc ribbon domain Methyltransf_2 PF00891.13 EIW71288.1 - 0.031 13.4 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Ubie_methyltran PF01209.13 EIW71288.1 - 0.036 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.6 EIW71288.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Glycos_transf_1 PF00534.15 EIW71289.1 - 3.7e-19 68.7 0.0 1.4e-18 66.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIW71289.1 - 3.9e-08 33.5 0.0 8.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2834 PF11196.3 EIW71289.1 - 0.00066 19.7 18.4 0.1 12.7 0.2 3.8 2 1 0 2 2 2 2 Protein of unknown function (DUF2834) DUF2975 PF11188.3 EIW71289.1 - 1.4 8.6 16.2 0.49 10.1 3.3 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) Potex_coat PF06184.6 EIW71290.1 - 0.16 11.3 0.1 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Potexvirus coat protein Yae1_N PF09811.4 EIW71291.1 - 6.1e-11 41.6 0.1 1.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Mob1_phocein PF03637.12 EIW71292.1 - 1.1e-26 93.5 0.0 1.4e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family TFIIA_gamma_N PF02268.11 EIW71293.1 - 5.3e-23 80.3 0.0 7.3e-23 79.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EIW71293.1 - 1.7e-21 75.7 0.0 2.4e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit MFS_1 PF07690.11 EIW71294.1 - 8.4e-32 110.2 29.1 8.4e-32 110.2 20.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PepSY_TM_2 PF13703.1 EIW71294.1 - 0.18 12.0 0.1 0.18 12.0 0.0 4.6 5 1 1 6 6 6 0 PepSY-associated TM helix DUF3759 PF12585.3 EIW71295.1 - 0.0045 16.8 0.2 0.013 15.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Cyclin_N PF00134.18 EIW71296.1 - 4.5e-45 152.3 0.6 8.4e-43 144.9 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIW71296.1 - 3.1e-33 114.2 0.2 6.7e-33 113.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DPM2 PF07297.7 EIW71297.1 - 1.5e-26 92.4 0.2 2.3e-26 91.8 0.2 1.2 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EIW71297.1 - 0.00095 18.7 0.4 0.0014 18.2 0.3 1.2 1 0 0 1 1 1 1 PIG-P UCR_6-4kD PF08997.5 EIW71297.1 - 0.023 14.4 0.2 0.05 13.3 0.1 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein DUF1469 PF07332.6 EIW71297.1 - 0.11 12.2 0.4 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) FAD_binding_2 PF00890.19 EIW71298.1 - 6.2e-85 285.5 0.6 8e-85 285.1 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EIW71298.1 - 1.2e-24 85.8 0.0 3.8e-24 84.2 0.0 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EIW71298.1 - 7.3e-13 48.1 0.5 1.8e-11 43.5 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW71298.1 - 3.7e-08 33.2 0.8 4.5e-07 29.7 0.3 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EIW71298.1 - 7.9e-08 31.7 1.3 1.9e-07 30.5 0.9 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW71298.1 - 5.3e-07 29.7 5.7 6.7e-05 22.8 3.9 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW71298.1 - 1.2e-06 27.2 7.4 0.00025 19.6 0.4 3.2 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 EIW71298.1 - 8.9e-06 24.8 2.1 0.002 17.0 0.8 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EIW71298.1 - 9.8e-06 25.7 0.6 6.4e-05 23.1 0.4 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW71298.1 - 0.00017 20.7 2.2 0.0069 15.5 0.6 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EIW71298.1 - 0.00097 18.2 1.5 0.0016 17.5 1.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIW71298.1 - 0.016 15.6 0.3 0.063 13.6 0.2 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIW71298.1 - 0.022 15.0 0.1 0.064 13.5 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EIW71298.1 - 0.11 12.2 0.4 1.1 9.0 0.2 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIW71298.1 - 0.14 11.0 0.2 0.21 10.4 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DEAD PF00270.24 EIW71300.1 - 7.5e-38 129.6 0.1 1.3e-36 125.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW71300.1 - 2.4e-19 68.9 0.2 3.9e-18 65.0 0.2 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW71300.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EIW71300.1 - 0.00028 19.7 0.0 0.00041 19.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 EIW71300.1 - 0.013 15.2 0.1 0.05 13.3 0.1 2.1 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EIW71300.1 - 0.069 13.2 0.7 1.9 8.6 1.0 2.8 2 1 0 2 2 2 0 AAA domain Ribosomal_S26e PF01283.14 EIW71301.1 - 1.6e-48 163.6 7.6 1.9e-48 163.4 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Serglycin PF04360.7 EIW71302.1 - 0.22 11.2 4.3 0.44 10.2 3.0 1.5 1 0 0 1 1 1 0 Serglycin zf-Tim10_DDP PF02953.10 EIW71303.1 - 4.5e-19 67.4 3.1 5.6e-19 67.1 2.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EIW71303.1 - 0.031 13.7 3.0 0.11 11.9 2.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Phasin_2 PF09361.5 EIW71303.1 - 0.031 14.2 0.1 0.099 12.6 0.0 1.7 1 1 1 2 2 2 0 Phasin protein Mmp37 PF09139.6 EIW71303.1 - 0.077 12.0 0.0 0.079 11.9 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 DUF4349 PF14257.1 EIW71304.1 - 0.029 13.5 0.1 0.041 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1957 PF09210.6 EIW71304.1 - 0.18 11.8 1.2 10 6.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1957) APG5 PF04106.7 EIW71306.1 - 3.4e-42 144.1 0.0 4.1e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 GCP5-Mod21 PF14609.1 EIW71306.1 - 0.035 12.2 0.1 0.046 11.8 0.0 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 MFS_1 PF07690.11 EIW71307.1 - 1.3e-11 43.8 38.0 8.5e-10 37.8 14.8 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily KH_1 PF00013.24 EIW71308.1 - 2.1e-40 136.1 6.6 5.3e-15 54.8 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EIW71308.1 - 9.2e-32 108.1 9.8 1.1e-10 40.9 0.4 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EIW71308.1 - 3e-17 61.9 2.1 4.6e-06 26.0 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EIW71308.1 - 5.7e-05 22.6 3.7 0.024 14.2 0.0 3.3 3 0 0 3 3 3 1 KH domain KH_5 PF13184.1 EIW71308.1 - 0.87 9.4 6.1 9.2 6.1 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain WAC_Acf1_DNA_bd PF10537.4 EIW71309.1 - 3.7e-33 113.7 0.4 9.7e-33 112.3 0.3 1.7 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EIW71309.1 - 4.8e-19 67.8 0.0 8.4e-19 67.0 0.0 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EIW71309.1 - 0.0002 21.1 0.0 0.00053 19.8 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EIW71309.1 - 0.0061 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 GAGA_bind PF06217.7 EIW71309.1 - 1.1 9.1 8.5 0.78 9.6 2.0 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family NDK PF00334.14 EIW71310.1 - 6.8e-51 171.6 0.0 8.8e-51 171.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase 2OG-FeII_Oxy_2 PF13532.1 EIW71311.1 - 4.9e-10 39.5 0.0 1.5e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Resolvase PF00239.16 EIW71312.1 - 0.0084 15.9 3.9 0.017 14.9 2.7 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC PF00098.18 EIW71312.1 - 0.023 14.6 4.3 0.044 13.7 3.0 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIW71312.1 - 0.038 13.4 0.2 0.073 12.5 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 EIW71313.1 - 2.3e-22 79.3 0.0 4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIW71313.1 - 8.3e-10 38.1 0.4 1.8e-09 37.1 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIW71313.1 - 0.0068 15.8 0.5 0.28 10.6 0.0 2.7 3 0 0 3 3 3 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 EIW71313.1 - 0.057 12.9 0.3 0.057 12.9 0.2 2.6 4 0 0 4 4 4 0 Integrase core domain 3Beta_HSD PF01073.14 EIW71316.1 - 2.3e-66 223.3 0.2 3.9e-58 196.3 0.2 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIW71316.1 - 1.8e-33 115.9 0.3 2.5e-33 115.5 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW71316.1 - 3.9e-16 59.5 0.0 5.8e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW71316.1 - 4.8e-14 51.8 1.0 3.2e-10 39.3 0.1 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EIW71316.1 - 3.1e-11 42.6 0.1 7.6e-11 41.4 0.1 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIW71316.1 - 1.8e-09 36.9 2.1 1.4e-07 30.7 1.3 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EIW71316.1 - 0.001 18.8 0.5 0.0068 16.0 0.3 2.3 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EIW71316.1 - 0.0012 18.8 0.6 0.01 15.7 0.4 2.4 1 1 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EIW71316.1 - 0.0057 16.6 0.2 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.8 EIW71316.1 - 0.0079 15.4 0.7 0.015 14.5 0.5 1.4 1 0 0 1 1 1 1 NmrA-like family Nup35_RRM PF05172.8 EIW71317.1 - 4.7e-08 32.7 0.0 7.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EIW71317.1 - 0.092 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 EIW71318.1 - 2.1e-14 53.2 0.0 2.1e-05 24.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW71318.1 - 9.8e-14 50.7 0.0 4.2e-05 23.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW71318.1 - 1.5e-13 50.3 0.0 3.1e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alginate_lyase PF05426.7 EIW71319.1 - 3.5e-15 56.1 0.7 4.7e-15 55.6 0.1 1.5 2 0 0 2 2 2 1 Alginate lyase SNARE PF05739.14 EIW71320.1 - 4.4e-15 55.1 2.2 9.5e-15 54.0 0.1 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EIW71320.1 - 2.1e-09 37.4 7.8 5.9e-09 36.0 0.2 2.6 2 1 0 2 2 2 1 Syntaxin AlaDh_PNT_C PF01262.16 EIW71320.1 - 0.087 12.3 0.6 0.23 10.9 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Syntaxin_2 PF14523.1 EIW71320.1 - 0.3 11.1 6.6 1.7 8.6 1.7 2.7 2 1 0 2 2 2 0 Syntaxin-like protein UFD1 PF03152.9 EIW71321.1 - 8.6e-62 207.3 0.0 2e-61 206.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EIW71321.1 - 0.00022 20.7 0.1 0.0027 17.3 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 OMPdecase PF00215.19 EIW71322.1 - 3.5e-64 216.2 0.1 5.6e-62 209.0 0.0 2.1 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Lon_C PF05362.8 EIW71323.1 - 5.7e-66 221.7 1.4 9.7e-66 220.9 1.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EIW71323.1 - 1.1e-21 77.3 0.0 3e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EIW71323.1 - 6.2e-09 35.4 0.4 3.1e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EIW71323.1 - 8.7e-09 35.2 0.0 2.7e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW71323.1 - 8.3e-07 29.1 4.2 2.7e-06 27.4 0.2 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EIW71323.1 - 9.8e-06 26.3 1.5 4.5e-05 24.2 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EIW71323.1 - 4.9e-05 23.4 1.2 0.0042 17.2 0.0 3.2 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EIW71323.1 - 0.00049 19.5 0.0 0.0014 18.0 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EIW71323.1 - 0.00097 18.2 0.0 0.0046 16.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EIW71323.1 - 0.0013 19.0 0.1 0.0038 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EIW71323.1 - 0.0015 18.1 0.0 0.0035 16.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIW71323.1 - 0.0025 17.7 0.0 0.0087 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EIW71323.1 - 0.0043 16.4 0.0 0.0099 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIW71323.1 - 0.0044 16.9 0.0 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW71323.1 - 0.0046 16.8 0.7 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW71323.1 - 0.014 15.5 0.0 0.047 13.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Rad17 PF03215.10 EIW71323.1 - 0.015 13.9 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 EIW71323.1 - 0.023 13.4 0.0 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_19 PF13245.1 EIW71323.1 - 0.026 14.2 0.1 0.078 12.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 EIW71323.1 - 0.026 14.0 0.2 0.11 12.0 0.1 2.1 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.16 EIW71323.1 - 0.027 13.6 0.4 0.095 11.8 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EIW71323.1 - 0.029 14.7 1.5 0.22 11.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EIW71323.1 - 0.034 13.2 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 EIW71323.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EIW71323.1 - 0.066 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 EIW71323.1 - 0.097 12.3 0.0 6 6.5 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase KTI12 PF08433.5 EIW71323.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Arch_ATPase PF01637.13 EIW71323.1 - 0.12 12.0 0.7 3.2 7.4 0.0 2.9 1 1 1 3 3 3 0 Archaeal ATPase NACHT PF05729.7 EIW71323.1 - 0.12 11.9 0.1 0.35 10.4 0.0 1.8 2 0 0 2 2 1 0 NACHT domain Aldo_ket_red PF00248.16 EIW71324.1 - 3e-47 160.8 0.0 3.6e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.22 EIW71325.1 - 4.3e-21 74.4 2.8 6.7e-08 32.1 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Mem_trans PF03547.13 EIW71325.1 - 0.0013 17.1 2.4 0.005 15.1 1.7 2.0 1 1 0 1 1 1 1 Membrane transport protein Zn_clus PF00172.13 EIW71326.1 - 7.7e-05 22.5 9.5 0.00014 21.6 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EIW71326.1 - 0.00015 21.4 0.0 0.00042 20.0 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EIW71326.1 - 0.055 13.5 0.1 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 PAS fold PAS_8 PF13188.1 EIW71326.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain RAM PF15320.1 EIW71326.1 - 0.15 12.3 5.3 0.16 12.2 0.2 2.6 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Tub_2 PF04525.7 EIW71327.1 - 1.2e-22 80.2 0.0 1.5e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 HpcH_HpaI PF03328.9 EIW71328.1 - 1.8e-31 108.7 0.0 2.1e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Phostensin_N PF13916.1 EIW71329.1 - 0.026 14.5 0.1 0.069 13.1 0.1 1.7 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Swi3 PF07962.7 EIW71330.1 - 2.7e-23 81.3 0.0 4.8e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Tub_2 PF04525.7 EIW71330.1 - 2.8e-12 46.4 0.0 4.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Tubby C 2 Methyltransf_11 PF08241.7 EIW71333.1 - 1.6e-09 38.1 0.0 2.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW71333.1 - 1.2e-08 34.6 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW71333.1 - 4.5e-08 33.6 0.0 5.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW71333.1 - 3.3e-06 27.4 0.0 4.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW71333.1 - 1.7e-05 25.1 0.0 2.7e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EIW71333.1 - 0.00015 21.3 0.0 0.0004 19.8 0.0 1.7 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 EIW71333.1 - 0.0011 18.7 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EIW71333.1 - 0.0091 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EIW71333.1 - 0.024 14.6 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EIW71333.1 - 0.031 13.9 0.0 0.04 13.5 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 EIW71333.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Bac_surface_Ag PF01103.18 EIW71334.1 - 1.6e-33 116.5 0.7 2.1e-33 116.1 0.5 1.1 1 0 0 1 1 1 1 Surface antigen adh_short PF00106.20 EIW71335.1 - 2.4e-16 60.1 5.9 1.5e-15 57.4 4.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW71335.1 - 1.1e-13 51.5 0.2 3.6e-13 49.8 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW71335.1 - 3.1e-08 33.4 2.8 3.7e-08 33.2 0.4 1.9 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.13 EIW71335.1 - 0.005 16.5 2.0 0.009 15.6 1.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EIW71335.1 - 0.033 13.2 0.1 0.062 12.3 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EIW71335.1 - 0.059 13.3 0.4 0.12 12.4 0.2 1.5 1 1 0 1 1 1 0 NADH(P)-binding Abhydrolase_2 PF02230.11 EIW71336.1 - 0.073 12.4 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase ICAP-1_inte_bdg PF10480.4 EIW71336.1 - 0.18 11.5 0.5 0.37 10.5 0.3 1.4 1 0 0 1 1 1 0 Beta-1 integrin binding protein SR-25 PF10500.4 EIW71337.1 - 3.4 7.0 15.5 0.41 10.0 7.7 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DnaJ PF00226.26 EIW71338.1 - 6.4e-18 64.2 0.1 6.4e-18 64.2 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain SpoVR PF04293.8 EIW71338.1 - 0.054 11.8 3.4 0.08 11.2 2.4 1.2 1 0 0 1 1 1 0 SpoVR like protein DUF2413 PF10310.4 EIW71338.1 - 1.2 7.9 17.4 1.9 7.2 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RRM_1 PF00076.17 EIW71339.1 - 6e-18 64.2 0.0 7.9e-18 63.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW71339.1 - 2.7e-14 52.9 0.0 3.8e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW71339.1 - 3.3e-09 36.4 0.0 4.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIW71339.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.5 1 1 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.1 EIW71339.1 - 0.051 13.3 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MMR_HSR1 PF01926.18 EIW71340.1 - 3e-19 69.0 0.0 3.5e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW71340.1 - 9.5e-07 28.2 0.0 1.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP1_OBG PF01018.17 EIW71340.1 - 0.00017 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 GTP1/OBG Miro PF08477.8 EIW71340.1 - 0.0012 19.3 0.0 0.0016 18.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIW71340.1 - 0.024 14.4 0.0 0.81 9.4 0.1 2.0 1 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.22 EIW71340.1 - 0.039 14.2 0.1 0.052 13.8 0.1 1.3 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 EIW71340.1 - 0.12 11.7 0.1 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Glyco_transf_18 PF15024.1 EIW71341.1 - 3.1e-08 32.4 0.0 4.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 18 TP_methylase PF00590.15 EIW71342.1 - 6.7e-41 140.3 0.1 2.9e-40 138.2 0.0 2.0 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EIW71342.1 - 1.7e-12 47.4 0.0 3.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EIW71342.1 - 1.3e-07 30.8 3.7 7.5e-05 21.9 0.3 2.9 3 0 0 3 3 3 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EIW71342.1 - 0.00014 20.7 0.8 0.00025 19.9 0.5 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central LSM PF01423.17 EIW71343.1 - 5.1e-15 54.7 0.5 5.1e-15 54.7 0.3 1.5 2 0 0 2 2 2 1 LSM domain Glyco_hydro_cc PF11790.3 EIW71345.1 - 3.2e-32 111.8 0.0 3.6e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Aldo_ket_red PF00248.16 EIW71346.1 - 1.9e-41 141.7 0.0 2.4e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SicP-binding PF09119.5 EIW71346.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 SicP binding CRAL_TRIO PF00650.15 EIW71347.1 - 3e-40 137.3 0.0 4.3e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EIW71347.1 - 5.5e-09 36.0 0.0 8.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIW71347.1 - 0.0031 17.6 1.9 0.007 16.4 1.3 1.7 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain NAC PF01849.13 EIW71348.1 - 8.2e-22 76.5 0.0 1.5e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EIW71348.1 - 0.00061 19.5 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EIW71348.1 - 0.0038 16.7 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain PASTA PF03793.14 EIW71348.1 - 0.029 14.0 1.0 1.3 8.6 0.0 3.4 4 1 0 4 4 4 0 PASTA domain Prefoldin_2 PF01920.15 EIW71349.1 - 1.3e-15 57.0 6.6 1.6e-15 56.7 4.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF3818 PF12825.2 EIW71349.1 - 0.0032 16.1 0.4 0.0042 15.7 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) Tropomyosin_1 PF12718.2 EIW71349.1 - 0.0056 16.5 2.8 0.0056 16.5 1.9 2.1 2 0 0 2 2 2 1 Tropomyosin like Coat_F PF07875.7 EIW71349.1 - 0.16 12.1 2.2 0.34 11.0 0.1 2.2 2 0 0 2 2 2 0 Coat F domain CENP-Q PF13094.1 EIW71349.1 - 1.5 8.8 10.9 0.23 11.4 2.0 2.4 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit 2OG-FeII_Oxy PF03171.15 EIW71350.1 - 7.2e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIW71350.1 - 0.086 13.3 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Eaf7 PF07904.8 EIW71352.1 - 9e-11 41.6 0.4 2.7e-10 40.0 0.0 2.0 3 0 0 3 3 3 1 Chromatin modification-related protein EAF7 UDPG_MGDP_dh_N PF03721.9 EIW71353.1 - 1.5e-60 203.7 0.0 2.7e-60 202.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EIW71353.1 - 4.1e-37 126.5 0.0 4e-35 120.1 0.0 2.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EIW71353.1 - 2.5e-31 107.7 0.0 5.1e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_7 PF13241.1 EIW71353.1 - 0.0017 18.6 0.0 0.57 10.4 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EIW71353.1 - 0.0018 18.0 0.1 0.0096 15.6 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4608 PF15381.1 EIW71353.1 - 0.035 14.2 0.4 0.23 11.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4608) 3HCDH_N PF02737.13 EIW71353.1 - 0.075 12.6 0.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EIW71353.1 - 0.089 11.7 0.0 0.21 10.5 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Mpv17_PMP22 PF04117.7 EIW71354.1 - 7.2e-25 86.4 0.4 1.1e-24 85.8 0.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Filament PF00038.16 EIW71355.1 - 6e-08 32.5 113.5 0.00064 19.2 16.2 4.8 1 1 2 4 4 4 4 Intermediate filament protein AIP3 PF03915.8 EIW71355.1 - 0.00061 18.8 19.9 0.00061 18.8 13.8 5.0 1 1 4 5 5 5 3 Actin interacting protein 3 IncA PF04156.9 EIW71355.1 - 3 7.3 128.1 0.074 12.6 12.5 7.1 1 1 5 6 6 6 0 IncA protein DUF1777 PF08648.7 EIW71356.1 - 1.4e-24 86.7 42.1 2e-24 86.3 29.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 EIW71356.1 - 0.66 8.3 21.6 0.73 8.2 15.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EIW71356.1 - 6.2 5.1 17.5 7.4 4.9 12.1 1.2 1 0 0 1 1 1 0 Daxx Family Fungal_trans PF04082.13 EIW71357.1 - 1.5e-12 46.9 0.0 3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW71357.1 - 9e-05 22.3 13.7 0.00016 21.4 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MULE PF10551.4 EIW71359.1 - 2.2e-13 50.1 1.4 1e-10 41.6 0.2 3.6 2 1 0 2 2 2 1 MULE transposase domain UCH_1 PF13423.1 EIW71359.1 - 0.037 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase rve PF00665.21 EIW71359.1 - 0.17 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain CPSF_A PF03178.10 EIW71360.1 - 8.8e-41 140.0 0.0 2.8e-40 138.3 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EIW71360.1 - 8.6e-28 96.7 0.0 1.6e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term ACPS PF01648.15 EIW71361.1 - 1.8e-14 53.5 0.0 3.9e-14 52.4 0.0 1.6 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily PAH PF02671.16 EIW71362.1 - 0.097 12.3 0.5 6.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Paired amphipathic helix repeat HALZ PF02183.13 EIW71362.1 - 0.47 10.2 9.6 15 5.4 0.0 4.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper ImmE5 PF11480.3 EIW71363.1 - 0.0026 17.5 0.4 0.0053 16.5 0.3 1.5 1 0 0 1 1 1 1 Colicin-E5 Imm protein DUF1757 PF08560.5 EIW71364.1 - 4.8e-08 32.8 0.0 6.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) Romo1 PF10247.4 EIW71364.1 - 0.15 12.2 4.6 0.91 9.7 0.2 2.7 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 MRP-S33 PF08293.6 EIW71365.1 - 8.2e-14 51.3 2.5 2.1e-09 37.2 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial ribosomal subunit S27 CAP59_mtransfer PF11735.3 EIW71366.1 - 1.3e-50 171.9 0.0 1.7e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 FAD_binding_1 PF00667.15 EIW71367.1 - 1.3e-49 168.6 0.0 2.2e-49 167.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EIW71367.1 - 6.1e-08 33.2 0.0 1.3e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIW71367.1 - 0.035 14.2 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain NAD_binding_8 PF13450.1 EIW71368.1 - 1.6e-11 44.0 0.0 4.7e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIW71368.1 - 1.1e-07 31.7 0.0 0.01 15.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EIW71368.1 - 3.6e-06 26.1 0.0 0.00039 19.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EIW71368.1 - 3.3e-05 23.1 0.0 0.00022 20.4 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EIW71368.1 - 9.9e-05 22.4 0.0 0.047 13.7 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW71368.1 - 0.068 13.0 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.2 EIW71369.1 - 4.2e-05 23.1 1.8 4.2e-05 23.1 1.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW71369.1 - 0.00014 21.4 4.5 0.0003 20.3 3.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EIW71369.1 - 0.034 13.8 0.3 0.073 12.8 0.2 1.6 1 0 0 1 1 1 0 F-box-like domain Pkinase PF00069.20 EIW71370.1 - 1e-53 182.1 0.0 1.5e-53 181.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71370.1 - 3.1e-20 72.3 0.0 5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW71370.1 - 0.00017 20.6 0.0 0.00034 19.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Arv1 PF04161.8 EIW71372.1 - 7.4e-21 75.0 0.0 1e-20 74.5 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family FtsX PF02687.16 EIW71372.1 - 0.24 11.1 5.1 0.37 10.5 0.7 2.3 2 0 0 2 2 2 0 FtsX-like permease family zf-CCHC PF00098.18 EIW71373.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW71373.1 - 0.27 11.5 9.2 0.069 13.3 4.2 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW71373.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW71374.1 - 0.12 11.7 0.1 0.3 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) SR-25 PF10500.4 EIW71374.1 - 0.94 8.9 28.4 0.08 12.3 9.1 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Usp PF00582.21 EIW71375.1 - 2e-13 50.7 0.9 3e-13 50.1 0.6 1.2 1 0 0 1 1 1 1 Universal stress protein family Homeobox PF00046.24 EIW71376.1 - 1.5e-16 59.7 0.4 3e-16 58.7 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIW71376.1 - 0.0001 21.9 0.2 0.0003 20.4 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Yippee-Mis18 PF03226.9 EIW71377.1 - 7e-19 67.6 0.4 8.6e-19 67.3 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 EIW71377.1 - 0.0035 17.2 1.9 0.13 12.1 0.1 2.1 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HNH_5 PF14279.1 EIW71377.1 - 0.0084 16.0 0.1 3.5 7.7 0.0 2.3 2 0 0 2 2 2 2 HNH endonuclease DUF2039 PF10217.4 EIW71377.1 - 0.014 15.3 0.5 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DZR PF12773.2 EIW71377.1 - 0.07 12.9 0.3 0.17 11.7 0.2 1.6 1 1 0 1 1 1 0 Double zinc ribbon DUF4451 PF14616.1 EIW71377.1 - 0.08 12.6 1.1 0.11 12.1 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) RNA_POL_M_15KD PF02150.11 EIW71377.1 - 0.1 12.2 2.2 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DUF4428 PF14471.1 EIW71377.1 - 0.13 12.0 0.8 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) RecR PF02132.10 EIW71377.1 - 1.6 8.2 3.6 9.3 5.7 0.1 2.2 2 0 0 2 2 2 0 RecR protein zinc_ribbon_2 PF13240.1 EIW71377.1 - 3.5 7.2 5.7 1.1 8.8 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Acetyltransf_3 PF13302.1 EIW71380.1 - 1.1e-12 48.3 0.0 5.2e-12 46.1 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain zf-MYND PF01753.13 EIW71380.1 - 1.3e-05 24.9 9.8 2.7e-05 23.9 6.8 1.5 1 0 0 1 1 1 1 MYND finger Acetyltransf_8 PF13523.1 EIW71380.1 - 6.7e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW71380.1 - 0.00045 20.2 0.0 0.00088 19.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DHHA2 PF02833.9 EIW71381.1 - 9.7e-15 54.8 0.0 1.7e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EIW71381.1 - 8.1e-07 28.7 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 DHH family Gal4_dimer PF03902.8 EIW71383.1 - 0.06 13.2 0.0 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 Gal4-like dimerisation domain SNARE_assoc PF09335.6 EIW71385.1 - 2.5e-10 40.6 9.2 3.8e-10 40.0 4.3 2.8 2 1 0 2 2 2 1 SNARE associated Golgi protein Ecl1 PF12855.2 EIW71386.1 - 4.2e-08 32.3 0.8 0.00014 21.0 0.0 2.4 2 0 0 2 2 2 2 Life-span regulatory factor PHD PF00628.24 EIW71387.1 - 0.014 15.1 5.1 0.014 15.1 3.6 3.3 3 1 0 3 3 3 0 PHD-finger DUF3459 PF11941.3 EIW71387.1 - 0.048 13.7 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) WD40 PF00400.27 EIW71388.1 - 1.6e-08 34.0 8.2 0.0073 16.1 0.0 4.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Kri1_C PF12936.2 EIW71389.1 - 6.2e-22 77.3 0.1 6.2e-22 77.3 0.1 3.5 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 EIW71389.1 - 1.9e-10 40.9 20.8 1.9e-10 40.9 14.4 4.8 3 2 0 3 3 3 1 KRI1-like family OAD_gamma PF04277.8 EIW71389.1 - 5.3 7.4 4.7 34 4.9 0.0 3.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain polyprenyl_synt PF00348.12 EIW71390.1 - 4.5e-46 156.7 0.0 1.1e-43 149.0 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EIW71390.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 RabGAP-TBC PF00566.13 EIW71392.1 - 4.2e-18 65.6 0.0 5.2e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL13 PF03487.8 EIW71393.1 - 0.18 11.5 0.0 0.51 10.0 0.0 1.7 1 0 0 1 1 1 0 Interleukin-13 Fer4 PF00037.22 EIW71394.1 - 5.6e-14 51.0 17.4 1.7e-08 33.7 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EIW71394.1 - 2.1e-12 47.1 10.6 3.3e-12 46.5 7.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EIW71394.1 - 7.8e-10 38.4 4.8 0.00011 21.9 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EIW71394.1 - 9.2e-10 38.1 22.5 5.6e-08 32.4 8.7 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EIW71394.1 - 1.8e-09 37.7 9.9 3.4e-09 36.8 6.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EIW71394.1 - 1.9e-09 38.1 7.8 9.6e-05 23.0 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.2 EIW71394.1 - 1.1e-08 34.4 13.9 9.2e-05 22.1 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EIW71394.1 - 1.5e-08 34.5 19.3 1.2e-05 25.2 7.9 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 EIW71394.1 - 7.6e-08 31.8 18.0 0.00072 19.3 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EIW71394.1 - 1.2e-06 28.7 8.8 0.00047 20.4 7.6 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 EIW71394.1 - 2.5e-06 27.3 12.1 0.00063 19.8 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 EIW71394.1 - 4e-05 23.9 9.7 0.025 14.9 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 EIW71394.1 - 5.2e-05 23.5 10.5 0.023 15.0 0.8 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 EIW71394.1 - 0.00014 22.3 8.2 0.052 14.1 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EIW71394.1 - 0.041 14.4 18.1 0.077 13.6 3.2 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EIW71394.1 - 0.054 13.6 4.1 0.26 11.4 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Peptidase_M16 PF00675.15 EIW71395.1 - 7e-39 132.9 0.0 2.6e-37 127.8 0.0 3.3 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIW71395.1 - 1.7e-35 122.4 0.0 2.6e-19 69.5 0.0 3.6 3 0 0 3 3 3 2 Peptidase M16 inactive domain Gp-FAR-1 PF05823.7 EIW71395.1 - 0.0014 18.5 0.5 0.0039 17.1 0.1 1.8 2 0 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PRONE PF03759.8 EIW71395.1 - 0.069 11.6 0.3 0.14 10.6 0.0 1.5 2 0 0 2 2 2 0 PRONE (Plant-specific Rop nucleotide exchanger) RRM_1 PF00076.17 EIW71396.1 - 3.5e-43 145.0 0.0 9.6e-13 47.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW71396.1 - 1.7e-30 104.7 0.0 4.4e-10 39.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW71396.1 - 5.3e-18 64.6 0.0 3.5e-05 23.5 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIW71396.1 - 0.00038 20.1 0.0 0.19 11.5 0.0 3.4 3 0 0 3 3 3 1 Limkain b1 Transformer PF06495.6 EIW71396.1 - 0.0071 16.2 29.2 0.015 15.1 20.2 1.5 1 0 0 1 1 1 1 Fruit fly transformer protein DUF566 PF04484.7 EIW71396.1 - 6.2 6.2 12.4 9.6 5.6 8.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) MIP-T3 PF10243.4 EIW71396.1 - 7.8 4.8 14.4 10 4.4 10.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Abhydrolase_6 PF12697.2 EIW71397.1 - 4.3e-33 115.1 0.0 5.2e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW71397.1 - 5.8e-16 58.7 0.0 1.4e-14 54.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW71397.1 - 7.1e-10 38.8 0.0 5e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EIW71397.1 - 0.0071 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein CBF PF03914.12 EIW71398.1 - 6.8e-46 155.7 0.0 6.8e-46 155.7 0.0 3.2 6 0 0 6 6 6 1 CBF/Mak21 family Adaptin_N PF01602.15 EIW71398.1 - 0.0026 16.1 0.0 1 7.5 0.1 2.4 2 0 0 2 2 2 2 Adaptin N terminal region DUF2428 PF10350.4 EIW71398.1 - 0.073 12.0 0.0 0.66 8.9 0.0 2.5 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) GRIM-19 PF06212.7 EIW71399.1 - 5.8e-33 113.3 0.0 6.7e-33 113.1 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein DUF865 PF05906.6 EIW71399.1 - 0.12 11.9 0.2 0.34 10.5 0.2 1.7 1 1 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) Histone PF00125.19 EIW71400.1 - 4e-14 52.4 0.1 4.9e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW71400.1 - 3.7e-05 23.8 0.0 4.9e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIW71400.1 - 0.00011 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIW71400.1 - 0.0012 18.8 0.1 0.0025 17.8 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIW71400.1 - 0.046 12.9 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PXA PF02194.10 EIW71402.1 - 4.9e-15 55.5 0.0 1.2e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 PXA domain ArfGap PF01412.13 EIW71403.1 - 2.5e-36 124.0 0.0 4.2e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Fungal_trans PF04082.13 EIW71404.1 - 1.5e-12 46.9 0.2 2.6e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW71404.1 - 2.1e-06 27.5 11.0 4.7e-06 26.4 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-ISL3 PF14690.1 EIW71404.1 - 1.2 9.2 9.5 0.26 11.3 1.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 RNA_pol_Rpb6 PF01192.17 EIW71405.1 - 4.6e-23 80.7 0.1 8.6e-23 79.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 WD40 PF00400.27 EIW71406.1 - 0.011 15.5 0.3 11 6.0 0.1 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Proteasome_A_N PF10584.4 EIW71406.1 - 0.011 15.0 0.3 0.024 13.9 0.2 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature hemP PF10636.4 EIW71406.1 - 0.13 11.9 0.4 0.42 10.2 0.1 2.0 2 0 0 2 2 2 0 Hemin uptake protein hemP BP28CT PF08146.7 EIW71407.1 - 4.4e-33 114.1 4.7 1.9e-32 112.0 0.4 3.6 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EIW71407.1 - 1.7e-07 31.2 5.9 5.5e-05 23.1 0.0 5.2 3 1 0 3 3 3 2 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EIW71407.1 - 8.5e-06 25.9 18.1 0.022 15.0 0.0 7.6 6 2 0 6 6 6 2 HEAT repeats HEAT PF02985.17 EIW71407.1 - 0.00035 20.4 9.3 0.62 10.2 0.1 7.0 6 0 0 6 6 6 1 HEAT repeat DRIM PF07539.7 EIW71407.1 - 0.00054 19.4 4.1 2.5 7.5 0.0 4.7 4 0 0 4 4 4 1 Down-regulated in metastasis HEAT_EZ PF13513.1 EIW71407.1 - 0.23 11.9 10.6 10 6.7 0.2 6.3 5 2 1 6 6 6 0 HEAT-like repeat Pkr1 PF08636.5 EIW71408.1 - 1.9e-07 31.0 10.1 2.3e-07 30.7 7.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4131 PF13567.1 EIW71408.1 - 0.054 12.8 0.2 0.055 12.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Viral_Beta_CD PF04530.7 EIW71408.1 - 0.13 12.4 0.1 0.18 12.0 0.0 1.2 1 1 0 1 1 1 0 Viral Beta C/D like family NKAIN PF05640.9 EIW71408.1 - 0.61 9.0 6.3 0.69 8.8 4.4 1.1 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein DUF4229 PF14012.1 EIW71408.1 - 7.7 6.4 9.2 9.8 6.1 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Fer2_4 PF13510.1 EIW71409.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MULE PF10551.4 EIW71410.1 - 4.7e-13 49.1 1.3 1e-10 41.5 0.2 3.5 2 1 0 2 2 2 1 MULE transposase domain UCH PF00443.24 EIW71410.1 - 2.3e-09 36.7 0.0 4.8e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW71410.1 - 0.034 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Romo1 PF10247.4 EIW71412.1 - 4.8e-26 90.7 11.0 6.1e-26 90.4 7.6 1.0 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 EIW71412.1 - 0.35 10.8 5.1 0.48 10.4 3.5 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family HUN PF08729.5 EIW71413.1 - 1.4e-10 40.8 0.1 5e-10 39.0 0.0 2.1 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 EIW71413.1 - 0.00086 19.0 0.4 0.0028 17.3 0.3 1.8 1 0 0 1 1 1 1 Ubinuclein conserved middle domain Nop14 PF04147.7 EIW71413.1 - 0.43 8.4 21.5 0.047 11.6 10.5 2.0 2 0 0 2 2 2 0 Nop14-like family Relaxase PF03432.9 EIW71413.1 - 0.89 8.8 7.2 0.13 11.6 1.0 2.4 2 1 0 2 2 2 0 Relaxase/Mobilisation nuclease domain TFIIA PF03153.8 EIW71413.1 - 7.4 6.3 15.3 0.64 9.8 6.5 2.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit TMEM51 PF15345.1 EIW71414.1 - 7.9e-05 22.4 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 MLANA PF14991.1 EIW71414.1 - 0.035 14.1 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A EB PF01683.13 EIW71414.1 - 0.99 9.5 28.4 0.11 12.6 2.0 4.1 2 1 1 3 3 3 0 EB module Pyr_redox_2 PF07992.9 EIW71415.1 - 0.00043 20.2 0.0 0.85 9.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW71415.1 - 0.00071 19.3 0.0 0.0037 17.0 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EIW71415.1 - 0.0058 16.7 0.0 2.3 8.2 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW71415.1 - 0.019 13.8 0.3 0.045 12.6 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 EIW71415.1 - 0.022 14.7 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW71415.1 - 0.031 14.6 0.0 7.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EIW71415.1 - 0.079 12.5 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EIW71415.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain zf-C2H2 PF00096.21 EIW71416.1 - 8e-06 25.8 7.8 0.00057 20.0 2.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW71416.1 - 1.3e-05 25.2 6.3 0.021 15.1 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger UQ_con PF00179.21 EIW71417.1 - 9.9e-22 76.8 0.0 1.7e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 EIW71417.1 - 2.9e-05 23.7 0.0 0.00016 21.4 0.1 2.3 2 0 0 2 2 2 1 UBA/TS-N domain IBR PF01485.16 EIW71417.1 - 2.2 8.2 7.9 51 3.8 5.8 2.3 1 1 1 2 2 2 0 IBR domain Carn_acyltransf PF00755.15 EIW71418.1 - 3.3e-130 434.9 0.0 1.6e-129 432.7 0.0 1.8 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Cytochrom_B558a PF05038.8 EIW71420.1 - 0.0033 17.0 0.1 0.0056 16.3 0.1 1.3 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit Tmemb_170 PF10190.4 EIW71421.1 - 0.00075 19.5 1.6 0.00075 19.5 1.1 1.9 2 0 0 2 2 2 1 Putative transmembrane protein 170 DUF4282 PF14110.1 EIW71421.1 - 4.7 7.4 9.4 16 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) zf-DBF PF07535.7 EIW71422.1 - 0.11 12.2 0.7 0.29 10.8 0.1 1.9 2 0 0 2 2 2 0 DBF zinc finger FYDLN_acid PF09538.5 EIW71422.1 - 2.2 8.9 10.6 6.3 7.4 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2011 PF09428.5 EIW71422.1 - 4 7.3 15.7 0.81 9.5 4.5 2.3 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) SAS4 PF15460.1 EIW71424.1 - 0.024 14.5 1.2 0.04 13.7 0.8 1.4 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 EIW71424.1 - 0.024 15.0 6.5 0.024 15.0 4.5 2.7 2 1 0 2 2 2 0 PEHE domain ORC6 PF05460.8 EIW71424.1 - 2.1 7.3 17.4 1.1 8.2 4.5 2.5 2 1 1 3 3 3 0 Origin recognition complex subunit 6 (ORC6) DUF953 PF06110.6 EIW71425.1 - 4.4e-16 58.3 0.0 4.7e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.1 EIW71425.1 - 3.6e-05 23.9 0.1 9e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 EIW71425.1 - 0.0007 19.2 0.1 0.0014 18.2 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin tRNA-synt_1c_C PF03950.13 EIW71425.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.3 1 1 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Thioredoxin_3 PF13192.1 EIW71425.1 - 0.087 12.6 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin domain BetaGal_dom2 PF10435.4 EIW71425.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 YcgR_2 PF12945.2 EIW71427.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Flagellar protein YcgR Myc_target_1 PF15179.1 EIW71428.1 - 0.78 9.2 3.9 0.56 9.7 0.1 2.4 3 0 0 3 3 3 0 Myc target protein 1 PAP2_3 PF14378.1 EIW71429.1 - 1.7e-35 122.3 9.7 1.7e-35 122.3 6.7 1.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.16 EIW71429.1 - 0.00041 20.0 7.2 0.00041 20.0 5.0 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EIW71429.1 - 0.00041 20.5 1.3 0.00041 20.5 0.9 2.1 3 0 0 3 3 3 1 PAP2 superfamily C-terminal zf-H2C2_2 PF13465.1 EIW71430.1 - 0.00086 19.4 0.8 0.00086 19.4 0.6 3.6 3 0 0 3 3 3 1 Zinc-finger double domain Aft1_HRR PF11787.3 EIW71430.1 - 0.24 12.4 7.2 0.063 14.3 2.0 2.3 2 0 0 2 2 2 0 Aft1 HRR domain zf-met2 PF12907.2 EIW71430.1 - 1.3 9.0 10.1 1.4 8.9 0.8 2.4 1 1 1 2 2 2 0 Zinc-binding zf-C2H2 PF00096.21 EIW71430.1 - 4.9 7.6 14.4 0.47 10.8 1.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Frataxin_Cyay PF01491.11 EIW71431.1 - 2.5e-25 88.3 0.0 3.1e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Aldedh PF00171.17 EIW71432.1 - 4.5e-114 381.3 0.0 5.4e-114 381.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family efThoc1 PF11957.3 EIW71433.1 - 8.7e-109 364.2 0.3 1.1e-108 363.9 0.2 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor CDC14 PF08045.6 EIW71434.1 - 3.2e-26 92.0 0.0 1.9e-22 79.6 0.0 2.2 2 0 0 2 2 2 2 Cell division control protein 14, SIN component Pex2_Pex12 PF04757.9 EIW71438.1 - 1.4e-40 139.1 9.0 5.6e-40 137.1 6.3 1.7 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EIW71438.1 - 9.9e-05 22.2 0.3 0.00025 20.9 0.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW71438.1 - 0.0024 17.6 0.1 0.0041 16.9 0.1 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EIW71438.1 - 0.0044 16.6 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW71438.1 - 0.037 13.8 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 Ring finger domain Vps39_2 PF10367.4 EIW71438.1 - 0.074 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 SRP14 PF02290.10 EIW71439.1 - 1e-13 50.9 0.1 1e-13 50.9 0.0 2.1 2 2 0 2 2 2 1 Signal recognition particle 14kD protein Pkinase PF00069.20 EIW71440.1 - 3.6e-59 200.0 0.0 2.9e-58 197.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.3 EIW71440.1 - 3.1e-47 160.7 0.0 5.8e-47 159.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 EIW71440.1 - 2.6e-42 144.6 0.0 5.7e-42 143.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EIW71440.1 - 0.00098 18.9 0.1 0.004 16.9 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-RING_2 PF13639.1 EIW71441.1 - 7e-14 51.3 4.7 1.1e-13 50.7 3.3 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EIW71441.1 - 2.1e-09 36.9 0.0 4.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-C3HC4_3 PF13920.1 EIW71441.1 - 4.9e-09 35.7 2.2 7.3e-09 35.1 1.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW71441.1 - 5.3e-08 32.7 4.9 8.9e-08 32.0 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW71441.1 - 2.2e-06 27.2 2.6 3.5e-06 26.6 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIW71441.1 - 9.6e-05 22.4 6.4 0.00019 21.4 4.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIW71441.1 - 0.00034 20.1 3.5 0.00056 19.5 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EIW71441.1 - 0.042 13.5 0.9 0.042 13.5 0.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EIW71441.1 - 0.075 12.7 1.8 0.17 11.6 1.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Aldo_ket_red PF00248.16 EIW71442.1 - 4e-50 170.2 0.0 5.3e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TTL PF03133.10 EIW71443.1 - 4e-37 127.7 0.0 6.1e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EIW71443.1 - 0.0041 16.8 0.0 0.032 13.9 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain FRG1 PF06229.7 EIW71444.1 - 5.5e-19 68.3 0.0 1.1e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EIW71444.1 - 0.0027 17.7 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 2 Fascin domain DUF569 PF04601.8 EIW71444.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF569) Aldedh PF00171.17 EIW71445.1 - 1.3e-11 43.5 8.2 9e-07 27.5 4.2 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Kin17_mid PF10357.4 EIW71446.1 - 7.7e-46 154.8 0.2 1.1e-45 154.3 0.1 1.2 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EIW71446.1 - 1.2e-06 28.4 2.7 2.4e-06 27.4 1.9 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW71446.1 - 6.9e-06 26.0 2.5 1.3e-05 25.2 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIW71446.1 - 0.018 15.1 0.8 0.044 13.9 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Menin PF05053.8 EIW71446.1 - 0.13 10.3 1.8 0.17 9.9 1.3 1.1 1 0 0 1 1 1 0 Menin DUF629 PF04780.7 EIW71446.1 - 0.33 9.4 1.5 0.72 8.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 EIW71446.1 - 0.49 10.8 2.7 1.1 9.7 1.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DAD PF02109.11 EIW71447.1 - 1.3e-39 134.7 1.0 1.4e-39 134.6 0.7 1.0 1 0 0 1 1 1 1 DAD family Mg_trans_NIPA PF05653.9 EIW71448.1 - 1.7e-59 201.2 9.0 1.1e-57 195.3 2.9 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EIW71448.1 - 6.3e-07 29.5 0.4 6.3e-07 29.5 0.3 3.4 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EIW71448.1 - 0.00014 21.9 2.7 0.00014 21.9 1.9 3.9 3 1 1 4 4 4 1 EamA-like transporter family Transket_pyr PF02779.19 EIW71449.1 - 2.7e-47 160.5 0.0 4.4e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIW71449.1 - 8.8e-38 129.0 0.6 1.8e-37 128.0 0.1 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Sen15 PF09631.5 EIW71450.1 - 3.6e-16 59.2 0.4 6.8e-13 48.7 0.3 2.1 1 1 0 1 1 1 1 Sen15 protein PsbP PF01789.11 EIW71450.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 PsbP IBN_N PF03810.14 EIW71451.1 - 1.7e-07 31.0 0.1 6.4e-06 25.9 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EIW71451.1 - 5.3e-07 29.8 0.1 0.0025 18.0 0.0 4.7 4 1 0 4 4 4 1 HEAT repeats Xpo1 PF08389.7 EIW71451.1 - 2.2e-05 24.4 0.3 0.0013 18.6 0.0 3.4 3 1 0 3 3 3 1 Exportin 1-like protein Cse1 PF08506.5 EIW71451.1 - 0.0014 17.2 0.0 0.0028 16.2 0.0 1.5 1 0 0 1 1 1 1 Cse1 HEAT PF02985.17 EIW71451.1 - 0.017 15.1 5.2 12 6.3 0.1 5.8 7 0 0 7 7 7 0 HEAT repeat Adaptin_N PF01602.15 EIW71451.1 - 0.029 12.7 2.6 0.11 10.8 0.0 2.6 2 1 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.1 EIW71451.1 - 0.31 11.5 5.9 33 5.1 0.0 4.8 4 0 0 4 4 4 0 HEAT-like repeat CAF-1_p150 PF11600.3 EIW71452.1 - 0.24 10.7 6.9 0.42 9.9 4.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sec1 PF00995.18 EIW71453.1 - 7.3e-134 447.4 0.0 9.3e-134 447.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PALP PF00291.20 EIW71454.1 - 3.6e-60 203.7 0.0 4.4e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GTP_EFTU PF00009.22 EIW71455.1 - 9.9e-48 162.0 0.0 1.5e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EIW71455.1 - 2.8e-39 133.3 0.0 5.6e-39 132.3 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EIW71455.1 - 1.2e-17 63.5 0.0 2.4e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIW71455.1 - 4.8e-09 36.2 0.2 9e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW71455.1 - 6.1e-05 22.9 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PPR_2 PF13041.1 EIW71455.1 - 0.00027 20.8 0.0 0.00074 19.4 0.0 1.8 1 0 0 1 1 1 1 PPR repeat family EFG_II PF14492.1 EIW71455.1 - 0.00077 19.2 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 EIW71455.1 - 0.021 15.2 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein PPR PF01535.15 EIW71455.1 - 0.065 13.2 0.3 0.71 9.9 0.0 3.0 2 0 0 2 2 2 0 PPR repeat IF-2B PF01008.12 EIW71456.1 - 5.7e-51 173.1 0.0 1.1e-50 172.1 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family Fungal_trans PF04082.13 EIW71458.1 - 2e-20 72.7 2.5 3.2e-20 72.1 1.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW71458.1 - 0.00021 21.0 7.4 0.00039 20.2 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Met_10 PF02475.11 EIW71459.1 - 5e-60 202.5 0.0 6.3e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EIW71459.1 - 0.00011 22.7 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW71459.1 - 0.00025 21.0 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIW71459.1 - 0.0024 17.0 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EIW71459.1 - 0.0074 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EIW71459.1 - 0.027 14.9 0.0 0.08 13.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 EIW71459.1 - 0.042 13.4 0.0 0.14 11.6 0.0 1.9 3 0 0 3 3 3 0 RNA cap guanine-N2 methyltransferase TRM PF02005.11 EIW71459.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.1 EIW71459.1 - 0.15 11.6 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain ABC_membrane PF00664.18 EIW71461.1 - 7.8e-34 117.3 11.8 1e-33 116.9 8.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EIW71461.1 - 5.3e-33 114.2 0.0 1e-32 113.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW71461.1 - 5.7e-07 29.7 0.0 0.015 15.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EIW71461.1 - 4.5e-06 26.0 0.9 0.0017 17.6 0.0 2.6 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain BpuJI_N PF11564.3 EIW71461.1 - 0.0019 17.2 0.6 0.5 9.2 0.2 2.2 2 0 0 2 2 2 2 Restriction endonuclease BpuJI - N terminal AAA_22 PF13401.1 EIW71461.1 - 0.0019 18.3 0.0 0.014 15.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW71461.1 - 0.002 18.1 0.1 0.0081 16.1 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EIW71461.1 - 0.003 18.3 0.0 0.007 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EIW71461.1 - 0.0037 17.4 0.0 0.018 15.2 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EIW71461.1 - 0.0053 16.2 0.2 0.026 14.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.1 EIW71461.1 - 0.011 15.6 0.0 0.064 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIW71461.1 - 0.017 15.4 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EIW71461.1 - 0.026 14.4 0.1 0.19 11.6 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 EIW71461.1 - 0.03 13.5 0.0 0.067 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EIW71461.1 - 0.047 13.6 0.1 0.82 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EIW71461.1 - 0.056 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 EIW71461.1 - 0.073 12.5 0.0 1.7 8.0 0.0 2.5 3 0 0 3 3 3 0 Guanylate kinase AAA_5 PF07728.9 EIW71461.1 - 0.09 12.4 0.0 0.37 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 EIW71461.1 - 0.11 11.0 0.2 0.36 9.3 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Rad17 PF03215.10 EIW71461.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Ank_4 PF13637.1 EIW71462.1 - 1.3e-12 47.8 0.1 7.8e-08 32.6 0.0 2.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW71462.1 - 7.4e-11 41.2 0.2 3.3e-05 23.7 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EIW71462.1 - 3.1e-10 40.2 0.1 0.00023 21.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIW71462.1 - 1.1e-09 38.2 0.2 1.8e-05 24.7 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EIW71462.1 - 1.8e-09 36.8 0.7 0.00042 19.9 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeat DRMBL PF07522.9 EIW71463.1 - 4.1e-28 97.6 0.0 8e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EIW71463.1 - 2.7e-10 40.0 0.1 6.3e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIW71463.1 - 0.0031 17.2 0.4 0.0071 16.0 0.3 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Drf_FH1 PF06346.7 EIW71464.1 - 2 7.9 14.2 6.8 6.1 9.9 1.8 1 1 0 1 1 1 0 Formin Homology Region 1 ERO1 PF04137.10 EIW71465.1 - 8.1e-123 409.9 0.0 1.1e-122 409.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Gly_transf_sug PF04488.10 EIW71466.1 - 1.3e-07 31.9 0.0 3.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EIW71466.1 - 0.002 16.6 0.0 0.0033 15.9 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain TPR_11 PF13414.1 EIW71467.1 - 0.0084 15.7 0.8 1.5 8.5 0.0 2.9 3 0 0 3 3 3 2 TPR repeat DUF4027 PF13219.1 EIW71467.1 - 0.096 12.1 0.5 0.19 11.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) TPR_7 PF13176.1 EIW71467.1 - 0.14 12.0 0.2 1.1e+02 2.9 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW71467.1 - 0.59 9.8 4.1 4.3 7.0 0.5 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIW71467.1 - 2.2 8.3 8.4 21 5.3 0.3 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4114 PF13448.1 EIW71468.1 - 0.069 13.9 0.1 0.32 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4114) DUF3094 PF11293.3 EIW71469.1 - 0.016 14.6 0.2 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Fer2_3 PF13085.1 EIW71470.1 - 1.5e-31 108.4 0.1 2.3e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EIW71470.1 - 1.6e-10 41.1 7.9 1.6e-10 41.1 5.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EIW71470.1 - 2.5e-08 33.8 6.5 2.5e-08 33.8 4.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EIW71470.1 - 7e-05 22.5 5.9 7e-05 22.5 4.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EIW71470.1 - 0.00012 22.2 6.1 0.018 15.2 0.2 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 EIW71470.1 - 0.0013 19.1 4.3 0.0013 19.1 3.0 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EIW71470.1 - 0.0044 17.3 6.8 0.0044 17.3 4.7 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EIW71470.1 - 0.014 15.1 0.8 0.014 15.1 0.6 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EIW71470.1 - 0.2 12.2 6.8 0.93 10.1 0.1 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain Pam17 PF08566.5 EIW71471.1 - 2.4e-61 206.4 0.0 2.9e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 F-box PF00646.28 EIW71472.1 - 0.026 14.1 2.9 0.045 13.4 1.0 2.1 2 0 0 2 2 2 0 F-box domain Elongin_A PF06881.6 EIW71472.1 - 0.084 13.2 0.8 0.17 12.2 0.6 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-C3HC4_2 PF13923.1 EIW71473.1 - 5.5 7.1 8.6 5.5 7.0 0.1 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ARF7EP_C PF14949.1 EIW71475.1 - 0.078 13.4 0.1 0.078 13.4 0.1 1.7 2 0 0 2 2 2 0 ARF7 effector protein C-terminus UvdE PF03851.9 EIW71476.1 - 1.1e-88 296.8 0.0 1.3e-88 296.6 0.0 1.0 1 0 0 1 1 1 1 UV-endonuclease UvdE Peptidase_M24 PF00557.19 EIW71477.1 - 6.5e-58 195.7 0.0 8.9e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EIW71477.1 - 3e-17 62.2 0.0 1.2e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Ldh_1_N PF00056.18 EIW71478.1 - 1.3e-45 154.7 0.0 2.1e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EIW71478.1 - 2.5e-44 151.0 0.0 3.8e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EIW71478.1 - 5.7e-05 21.9 0.0 9.4e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EIW71478.1 - 0.032 13.3 0.3 0.12 11.3 0.0 2.1 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.15 EIW71478.1 - 0.035 14.0 0.4 0.074 12.9 0.0 1.8 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 EIW71478.1 - 0.039 13.9 0.1 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 EIW71478.1 - 0.044 14.0 0.4 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DDE_3 PF13358.1 EIW71480.1 - 1.1e-13 51.1 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EIW71480.1 - 0.00021 21.3 0.0 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DUF3136 PF11334.3 EIW71480.1 - 0.015 14.6 0.3 0.03 13.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) DDE_3 PF13358.1 EIW71488.1 - 3.8e-20 72.1 0.0 6.4e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIW71488.1 - 6e-07 29.4 0.2 1.1e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Transposase Resolvase PF00239.16 EIW71490.1 - 0.028 14.2 1.8 0.028 14.2 1.2 1.7 2 0 0 2 2 2 0 Resolvase, N terminal domain zf-CCHC_2 PF13696.1 EIW71490.1 - 0.031 13.7 0.2 0.064 12.7 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EIW71490.1 - 0.038 13.9 4.3 0.038 13.9 3.0 1.6 2 0 0 2 2 2 0 Zinc knuckle GPI-anchored PF10342.4 EIW71492.1 - 8.5e-12 45.3 9.7 8.5e-12 45.3 6.7 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AdoMet_MTase PF07757.8 EIW71493.1 - 1.9e-26 92.3 0.1 1.3e-25 89.7 0.1 2.2 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EIW71493.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S27e PF01667.12 EIW71494.1 - 1.8e-27 94.6 6.6 2.2e-27 94.3 4.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EIW71494.1 - 0.0014 18.5 1.0 0.0014 18.4 0.7 1.2 1 0 0 1 1 1 1 IBR domain zinc_ribbon_5 PF13719.1 EIW71494.1 - 0.028 13.9 1.9 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIW71494.1 - 0.036 13.7 2.6 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 EIW71494.1 - 0.15 11.8 3.4 0.3 10.8 2.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 EIW71494.1 - 0.32 10.2 4.4 2.1 7.6 0.8 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF2752 PF10825.3 EIW71494.1 - 0.41 10.7 2.8 2.4 8.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2752) Prok-RING_1 PF14446.1 EIW71494.1 - 0.43 10.3 3.1 0.61 9.8 2.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2HC5 PF06221.8 EIW71494.1 - 0.67 9.7 5.4 0.56 9.9 1.4 2.2 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Scramblase PF03803.10 EIW71495.1 - 6.4e-61 205.2 0.0 7.9e-61 204.9 0.0 1.0 1 0 0 1 1 1 1 Scramblase WD40 PF00400.27 EIW71496.1 - 1.8e-22 78.3 23.6 5.9e-09 35.4 0.6 6.3 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EIW71496.1 - 0.0008 17.6 0.4 0.0012 17.0 0.3 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PD40 PF07676.7 EIW71496.1 - 0.099 12.3 0.4 1.1 9.0 0.0 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 EIW71497.1 - 1.4e-05 24.8 0.5 0.0048 16.7 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EIW71497.1 - 0.0031 16.9 0.0 1.9 8.0 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.10 EIW71497.1 - 0.048 12.7 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region CNH PF00780.17 EIW71497.1 - 0.058 12.8 0.1 0.76 9.1 0.1 2.6 2 1 0 2 2 2 0 CNH domain Abhydrolase_1 PF00561.15 EIW71498.1 - 9.8e-19 67.8 0.0 7.3e-15 55.1 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIW71498.1 - 2.1e-13 50.6 0.9 2.6e-12 47.1 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIW71498.1 - 0.0011 18.4 0.2 0.0017 17.8 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_4 PF08386.5 EIW71498.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Pkinase PF00069.20 EIW71499.1 - 1.2e-33 116.4 0.0 1.4e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71499.1 - 1.3e-13 50.5 0.0 1.8e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW71499.1 - 0.012 14.5 0.0 0.025 13.5 0.0 1.4 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EIW71499.1 - 0.27 10.9 3.9 2.9 7.5 1.4 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family BRCT PF00533.21 EIW71500.1 - 0.00079 19.5 0.0 0.0023 18.0 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EIW71501.1 - 2e-42 144.5 0.0 5.4e-42 143.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW71501.1 - 2.8e-06 27.5 0.0 0.00042 20.4 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW71501.1 - 3.9e-06 26.6 0.0 2.7e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIW71501.1 - 0.00021 21.2 0.0 0.00064 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EIW71501.1 - 0.00022 21.2 0.0 0.00088 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EIW71501.1 - 0.00042 21.1 0.1 0.0013 19.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EIW71501.1 - 0.00067 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EIW71501.1 - 0.0037 16.9 0.1 0.0082 15.8 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EIW71501.1 - 0.0045 16.0 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EIW71501.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIW71501.1 - 0.012 15.5 0.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIW71501.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIW71501.1 - 0.019 15.0 0.0 0.042 13.8 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EIW71501.1 - 0.019 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 EIW71501.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EIW71501.1 - 0.029 14.0 0.5 7 6.2 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase IstB_IS21 PF01695.12 EIW71501.1 - 0.03 13.7 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EIW71501.1 - 0.035 14.4 0.1 0.1 12.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.8 EIW71501.1 - 0.044 12.4 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EIW71501.1 - 0.051 12.7 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EIW71501.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW71501.1 - 0.065 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 EIW71501.1 - 0.12 11.8 0.0 0.36 10.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 EIW71502.1 - 1.9e-110 367.4 0.0 2.8e-110 366.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIW71502.1 - 4.1e-25 88.4 2.1 8.3e-25 87.4 1.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIW71502.1 - 1.7e-14 53.7 2.9 5.1e-14 52.2 2.0 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Nop52 PF05997.7 EIW71503.1 - 1.1e-59 201.4 0.0 1.4e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.1 EIW71503.1 - 0.064 12.5 0.0 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II 3HCDH PF00725.17 EIW71503.1 - 0.089 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain zf-Tim10_DDP PF02953.10 EIW71504.1 - 2.1e-20 71.7 3.8 2.6e-20 71.4 2.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PMEI PF04043.10 EIW71504.1 - 0.00018 21.4 0.6 0.0002 21.2 0.4 1.1 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor MAR_sialic_bdg PF10564.4 EIW71504.1 - 0.05 13.3 0.7 0.059 13.1 0.5 1.1 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat XAP5 PF04921.9 EIW71505.1 - 4.6e-88 294.8 7.2 4.6e-88 294.8 5.0 1.9 1 1 1 2 2 2 1 XAP5, circadian clock regulator p450 PF00067.17 EIW71506.1 - 5.1e-59 200.0 0.0 1.3e-58 198.6 0.0 1.6 1 1 1 2 2 2 1 Cytochrome P450 p450 PF00067.17 EIW71507.1 - 7.4e-49 166.5 0.0 1.1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NADH_dh_m_C1 PF15088.1 EIW71507.1 - 0.0019 17.6 1.3 0.013 15.0 0.2 2.4 2 0 0 2 2 2 1 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial LTV PF04180.9 EIW71508.1 - 6.5e-60 203.8 13.6 6.6e-57 193.9 2.1 3.3 2 1 0 2 2 2 2 Low temperature viability protein Ras PF00071.17 EIW71509.1 - 1.4e-47 161.1 0.0 1.6e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW71509.1 - 6.2e-14 52.5 0.0 1e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW71509.1 - 5.1e-08 32.3 0.0 7.3e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW71509.1 - 0.0093 15.1 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EIW71509.1 - 0.023 13.3 0.9 2.5 6.6 0.0 2.8 2 1 1 3 3 3 0 G-protein alpha subunit STAS PF01740.16 EIW71509.1 - 0.067 12.6 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 STAS domain DUF3767 PF12597.3 EIW71510.1 - 1.4e-26 92.4 0.0 2.8e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Med15 PF09606.5 EIW71510.1 - 0.037 12.2 2.9 0.044 11.9 2.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pkinase PF00069.20 EIW71511.1 - 1.5e-39 135.7 0.0 2.7e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71511.1 - 3.1e-18 65.7 0.0 8.7e-17 61.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW71511.1 - 2.1e-05 23.6 0.0 0.023 13.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EIW71511.1 - 0.053 13.2 0.0 0.55 9.9 0.0 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Rho_N PF07498.7 EIW71512.1 - 1.2e-06 28.1 0.1 2.3e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.22 EIW71512.1 - 0.00022 20.6 0.3 0.00055 19.3 0.2 1.7 1 1 0 1 1 1 1 SAP domain APP_Cu_bd PF12924.2 EIW71512.1 - 0.041 14.3 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD Ribosomal_L6 PF00347.18 EIW71513.1 - 8.3e-22 77.4 0.2 3e-14 53.2 0.0 3.5 4 0 0 4 4 4 3 Ribosomal protein L6 Bromodomain PF00439.20 EIW71514.1 - 5.7e-52 173.5 0.0 5.9e-20 70.9 0.0 3.8 3 0 0 3 3 3 3 Bromodomain zf-C2H2_jaz PF12171.3 EIW71514.1 - 0.00027 20.9 0.7 0.023 14.8 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Peptidase_M1 PF01433.15 EIW71514.1 - 0.0019 17.3 0.0 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 zf-C2H2 PF00096.21 EIW71514.1 - 0.091 13.1 3.3 8.6 6.9 0.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type adh_short PF00106.20 EIW71515.1 - 1.4e-14 54.4 0.3 7e-14 52.0 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW71515.1 - 8.1e-14 51.9 0.1 1.3e-13 51.3 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW71515.1 - 3.5e-06 26.8 0.0 6.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EIW71515.1 - 0.032 13.8 1.3 0.065 12.8 0.7 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EIW71515.1 - 0.035 13.9 0.6 0.076 12.8 0.4 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 EIW71515.1 - 0.052 12.6 0.1 0.097 11.7 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EIW71515.1 - 0.17 12.1 0.6 0.4 10.9 0.4 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding WD40 PF00400.27 EIW71516.1 - 2.1e-55 182.7 19.8 2.1e-08 33.7 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW71516.1 - 6.4e-05 21.2 2.6 1.2 7.1 0.0 4.0 1 1 3 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW71516.1 - 0.0011 17.7 0.1 0.63 8.7 0.1 2.6 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 EIW71516.1 - 0.025 14.0 0.2 1.7 8.0 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain Lyase_1 PF00206.15 EIW71517.1 - 3.2e-22 79.1 0.0 4.8e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EIW71517.1 - 2.2e-15 56.4 0.0 5.2e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.6 EIW71517.1 - 0.05 13.0 0.1 0.099 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Ldh_1_N PF00056.18 EIW71518.1 - 1.3e-41 141.7 0.0 1.8e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EIW71518.1 - 1e-36 126.2 0.0 1.4e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EIW71518.1 - 0.052 12.2 0.0 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Thioredoxin PF00085.15 EIW71519.1 - 1.2e-26 92.4 0.1 1.4e-26 92.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIW71519.1 - 2.1e-06 27.7 0.0 4.9e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EIW71519.1 - 2.3e-06 27.7 0.1 1.3e-05 25.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EIW71519.1 - 8.1e-05 22.3 0.1 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EIW71519.1 - 0.00031 20.2 0.0 0.00037 20.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EIW71519.1 - 0.00077 19.0 0.3 0.0083 15.6 0.1 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 EIW71519.1 - 0.0099 15.8 0.1 0.016 15.2 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 EIW71519.1 - 0.027 14.4 0.5 0.054 13.4 0.3 1.7 1 1 0 1 1 1 0 Glutaredoxin Ricin_B_lectin PF00652.17 EIW71520.1 - 2.4e-07 30.8 1.5 3.9e-07 30.1 1.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIW71520.1 - 0.057 13.7 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like RFX_DNA_binding PF02257.10 EIW71521.1 - 1.4e-26 92.3 0.1 3.8e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 EIW71521.1 - 0.0099 16.1 0.0 0.034 14.3 0.0 1.8 2 0 0 2 2 2 1 Poxvirus D5 protein-like APOBEC_N PF08210.6 EIW71521.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain GCIP PF13324.1 EIW71522.1 - 1e-05 24.9 0.7 1e-05 24.9 0.5 1.8 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting CPT PF07931.7 EIW71522.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MAAL_C PF07476.6 EIW71522.1 - 0.033 13.1 0.4 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Rogdi_lz PF10259.4 EIW71522.1 - 0.18 10.9 3.0 0.27 10.2 2.1 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein GTP_EFTU PF00009.22 EIW71523.1 - 5.9e-59 198.6 0.2 8.7e-59 198.1 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIW71523.1 - 2.8e-27 94.7 0.3 7.1e-27 93.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIW71523.1 - 2.7e-15 56.2 4.7 2.7e-15 56.2 3.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW71523.1 - 5.4e-06 26.3 0.1 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EIW71523.1 - 6.9e-05 22.4 0.7 0.00015 21.3 0.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EIW71523.1 - 0.00061 20.2 0.1 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EIW71523.1 - 0.015 14.7 0.7 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EIW71523.1 - 0.026 13.9 1.2 0.037 13.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EIW71523.1 - 0.029 13.7 1.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cornifin PF02389.10 EIW71524.1 - 0.043 13.5 1.8 0.066 12.9 1.2 1.2 1 0 0 1 1 1 0 Cornifin (SPRR) family Myosin_tail_1 PF01576.14 EIW71525.1 - 0.0064 14.2 0.6 0.0075 14.0 0.4 1.0 1 0 0 1 1 1 1 Myosin tail Fmp27_WPPW PF10359.4 EIW71525.1 - 0.017 13.5 0.1 0.02 13.3 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CorC_HlyC PF03471.12 EIW71525.1 - 0.03 14.0 0.0 4.6 7.0 0.0 2.1 1 1 1 2 2 2 0 Transporter associated domain AATF-Che1 PF13339.1 EIW71525.1 - 0.034 14.3 2.0 0.062 13.4 1.4 1.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TMF_TATA_bd PF12325.3 EIW71525.1 - 0.036 13.7 0.6 0.054 13.2 0.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TylF PF05711.6 EIW71525.1 - 0.048 12.7 0.1 0.074 12.1 0.0 1.3 1 1 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Nup54 PF13874.1 EIW71525.1 - 0.074 12.7 0.5 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 IncA PF04156.9 EIW71525.1 - 1.4 8.4 5.4 1.8 8.1 3.3 1.4 1 1 0 1 1 1 0 IncA protein Acyl-CoA_dh_1 PF00441.19 EIW71526.1 - 5.1e-27 94.8 0.1 7.7e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIW71526.1 - 9.2e-27 93.8 0.0 2.1e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EIW71526.1 - 1e-21 76.1 0.1 2.7e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIW71526.1 - 5.6e-08 33.1 0.0 9.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EIW71526.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Smg4_UPF3 PF03467.10 EIW71527.1 - 7.1e-24 84.7 0.0 3.7e-23 82.4 0.0 2.1 1 1 0 1 1 1 1 Smg-4/UPF3 family Totivirus_coat PF05518.6 EIW71527.1 - 1.3 6.7 9.9 2.1 6.0 6.9 1.3 1 0 0 1 1 1 0 Totivirus coat protein Hanta_nucleocap PF00846.13 EIW71528.1 - 0.15 10.7 1.0 0.22 10.1 0.7 1.2 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein 60KD_IMP PF02096.15 EIW71530.1 - 1.6e-40 138.8 1.8 2.1e-40 138.5 1.3 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Vitellogenin_N PF01347.17 EIW71530.1 - 0.17 10.0 0.0 0.24 9.5 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region Oxidored_q6 PF01058.17 EIW71531.1 - 2.2e-22 79.0 0.1 3.3e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit BiPBP_C PF06832.7 EIW71531.1 - 0.12 12.3 0.1 4.5 7.2 0.0 2.4 1 1 1 2 2 2 0 Penicillin-Binding Protein C-terminus Family Xpo1 PF08389.7 EIW71532.1 - 3.2e-21 75.8 0.0 6.3e-20 71.5 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein AFG1_ATPase PF03969.11 EIW71533.1 - 2.7e-47 161.3 0.0 6.4e-24 84.4 0.0 3.7 3 1 1 4 4 4 3 AFG1-like ATPase AAA_16 PF13191.1 EIW71533.1 - 2.2e-05 24.5 0.6 0.00014 21.9 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EIW71533.1 - 0.00014 21.3 0.0 0.069 12.5 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein KAP_NTPase PF07693.9 EIW71533.1 - 0.0013 17.8 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_5 PF07728.9 EIW71533.1 - 0.0017 18.0 0.0 0.005 16.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIW71533.1 - 0.0028 17.7 0.0 0.023 14.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EIW71533.1 - 0.0033 16.6 0.0 0.0081 15.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EIW71533.1 - 0.0035 17.0 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EIW71533.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EIW71533.1 - 0.015 15.5 0.0 0.092 12.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EIW71533.1 - 0.029 13.4 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EIW71533.1 - 0.03 14.2 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EIW71533.1 - 0.033 13.8 0.3 1.2 8.8 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_17 PF13207.1 EIW71533.1 - 0.035 14.9 0.2 0.19 12.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EIW71533.1 - 0.045 12.6 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 EIW71533.1 - 0.068 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EIW71533.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIW71533.1 - 0.15 11.4 0.0 0.61 9.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain GST_N_3 PF13417.1 EIW71534.1 - 2.8e-12 46.6 0.1 3.5e-11 43.1 0.0 2.5 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW71534.1 - 4.5e-07 29.7 0.0 2.5e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW71534.1 - 0.00035 20.3 0.0 0.00088 19.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW71534.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW71534.1 - 0.0014 18.7 0.0 0.0072 16.4 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain ABC_tran PF00005.22 EIW71535.1 - 2.5e-46 157.3 0.0 6.2e-26 91.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW71535.1 - 1.9e-36 125.9 25.1 4.2e-18 65.7 6.4 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EIW71535.1 - 1e-09 37.9 0.0 0.00099 18.4 1.2 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW71535.1 - 6.9e-07 29.5 0.1 0.0037 17.2 0.1 3.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIW71535.1 - 0.00017 21.0 0.0 0.46 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW71535.1 - 0.0012 19.0 0.3 1.9 8.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIW71535.1 - 0.0025 17.3 1.0 1.5 8.1 0.0 3.0 2 1 0 3 3 3 1 AAA-like domain AAA_16 PF13191.1 EIW71535.1 - 0.0029 17.6 0.7 0.27 11.1 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EIW71535.1 - 0.0038 17.1 0.2 0.65 9.9 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EIW71535.1 - 0.0044 15.9 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 EIW71535.1 - 0.0089 15.5 1.5 1.9 8.0 0.0 3.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain KaiC PF06745.8 EIW71535.1 - 0.015 14.3 0.2 3.7 6.6 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.1 EIW71535.1 - 0.075 13.3 2.1 11 6.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EIW71535.1 - 0.1 13.1 1.4 6.5 7.2 0.1 2.9 3 0 0 3 3 2 0 Miro-like protein AAA_17 PF13207.1 EIW71535.1 - 0.13 13.0 0.0 1.1 10.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EIW71535.1 - 0.15 11.7 1.0 15 5.2 0.1 2.6 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 EIW71535.1 - 0.15 11.2 0.0 12 5.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 EIW71535.1 - 0.16 11.6 0.1 2.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EIW71535.1 - 0.66 9.3 2.4 2.1 7.7 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mo25 PF08569.6 EIW71536.1 - 4.5e-113 377.6 12.5 3.6e-112 374.7 8.6 1.9 1 1 0 1 1 1 1 Mo25-like RepA_N PF06970.6 EIW71536.1 - 0.25 11.1 2.5 0.47 10.2 0.8 2.2 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus V-SNARE PF05008.10 EIW71537.1 - 1.2e-19 70.2 6.3 2.7e-19 69.1 2.4 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EIW71537.1 - 4.3e-14 52.3 7.6 5.8e-12 45.5 1.5 3.3 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.6 EIW71537.1 - 0.00014 19.6 3.3 0.048 11.2 0.1 2.0 2 0 0 2 2 2 2 Prominin Baculo_PEP_C PF04513.7 EIW71537.1 - 0.00041 20.1 0.2 1.3 8.8 0.1 2.5 2 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 EIW71537.1 - 0.0025 17.5 5.4 0.39 10.4 0.2 2.2 2 0 0 2 2 2 2 Laminin Domain II EzrA PF06160.7 EIW71537.1 - 0.0096 14.1 0.3 0.0096 14.1 0.2 2.3 3 0 0 3 3 2 1 Septation ring formation regulator, EzrA YukC PF10140.4 EIW71537.1 - 0.013 14.0 2.6 0.062 11.8 0.1 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Tektin PF03148.9 EIW71537.1 - 0.026 13.0 0.4 0.026 13.0 0.3 2.1 2 0 0 2 2 2 0 Tektin family Laminin_I PF06008.9 EIW71537.1 - 0.031 13.5 7.9 0.053 12.8 0.4 2.3 2 0 0 2 2 2 0 Laminin Domain I WEMBL PF05701.6 EIW71537.1 - 0.064 11.7 8.7 0.43 8.9 3.0 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF793 PF05633.6 EIW71537.1 - 0.066 11.9 1.4 0.12 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF793) CDC37_N PF03234.9 EIW71537.1 - 0.07 13.4 3.5 1.6 9.0 0.5 2.2 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding PhoU_div PF01865.11 EIW71537.1 - 0.075 12.1 1.7 1.8 7.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF47 Flagellin_N PF00669.15 EIW71537.1 - 0.11 12.2 6.8 3.5 7.4 0.9 2.8 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region DegS PF05384.6 EIW71537.1 - 0.12 11.6 4.8 0.62 9.2 0.1 2.7 2 1 0 2 2 2 0 Sensor protein DegS PilJ PF13675.1 EIW71537.1 - 0.22 11.8 5.0 0.5 10.7 0.7 2.5 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fusion_gly PF00523.13 EIW71537.1 - 0.26 9.3 2.5 0.48 8.4 0.2 2.1 2 1 0 2 2 2 0 Fusion glycoprotein F0 Synaptobrevin PF00957.16 EIW71537.1 - 0.27 10.8 6.9 0.068 12.7 0.8 2.5 3 0 0 3 3 3 0 Synaptobrevin FliJ PF02050.11 EIW71537.1 - 0.33 11.0 9.1 2.5 8.1 1.8 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein DUF883 PF05957.8 EIW71537.1 - 0.33 11.3 9.4 3.6 8.0 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) GvpL_GvpF PF06386.6 EIW71537.1 - 0.37 10.3 7.3 0.055 13.0 2.0 1.7 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Exonuc_VII_L PF02601.10 EIW71537.1 - 0.69 9.0 6.3 0.48 9.5 1.2 1.9 1 1 0 2 2 2 0 Exonuclease VII, large subunit DUF1640 PF07798.6 EIW71537.1 - 0.77 9.7 7.0 4.4 7.3 4.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Prefoldin PF02996.12 EIW71537.1 - 0.94 9.1 8.1 4.6 6.9 0.1 3.3 2 1 1 3 3 3 0 Prefoldin subunit Spc7 PF08317.6 EIW71537.1 - 1 7.9 7.1 0.38 9.3 2.2 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein HisKA_3 PF07730.8 EIW71537.1 - 1.3 9.4 8.5 5 7.5 0.1 3.4 2 2 1 3 3 3 0 Histidine kinase DUF106 PF01956.11 EIW71537.1 - 1.5 8.2 5.6 17 4.9 3.9 2.4 1 1 0 1 1 1 0 Integral membrane protein DUF106 YlqD PF11068.3 EIW71537.1 - 1.8 8.6 9.6 1.7 8.6 2.7 2.3 2 0 0 2 2 2 0 YlqD protein Tropomyosin_1 PF12718.2 EIW71537.1 - 1.8 8.3 7.9 5.3 6.8 2.2 2.3 2 0 0 2 2 2 0 Tropomyosin like Snapin_Pallidin PF14712.1 EIW71537.1 - 1.9 8.8 7.9 0.52 10.6 2.6 2.2 2 2 0 2 2 2 0 Snapin/Pallidin DUF2317 PF10079.4 EIW71537.1 - 5 5.6 7.4 1.4 7.3 0.4 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF1664 PF07889.7 EIW71537.1 - 5.6 6.7 7.4 25 4.6 1.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SNARE PF05739.14 EIW71537.1 - 8.6 6.1 9.6 4.2 7.1 0.3 3.7 3 1 1 4 4 4 0 SNARE domain G_glu_transpept PF01019.16 EIW71538.1 - 5.2e-137 457.4 0.0 6.2e-137 457.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase He_PIG PF05345.7 EIW71539.1 - 1.2e-15 57.1 26.9 8.6e-05 22.4 4.9 6.4 5 1 1 6 6 6 4 Putative Ig domain SKG6 PF08693.5 EIW71539.1 - 0.0021 17.3 0.2 0.006 15.8 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sarcoglycan_2 PF05510.8 EIW71539.1 - 0.0037 15.6 1.3 4.8 5.3 0.0 3.8 4 0 0 4 4 4 2 Sarcoglycan alpha/epsilon Adeno_E3_CR2 PF02439.10 EIW71539.1 - 0.0041 16.6 0.2 0.01 15.3 0.2 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EIW71539.1 - 0.0069 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.7 EIW71539.1 - 0.025 13.9 0.0 0.025 13.9 0.0 2.5 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor TMEM154 PF15102.1 EIW71539.1 - 0.036 13.7 0.0 0.14 11.8 0.0 2.0 1 0 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.11 EIW71539.1 - 0.12 10.5 0.0 0.22 9.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E IncA PF04156.9 EIW71542.1 - 0.6 9.6 2.2 11 5.6 0.1 2.1 1 1 1 2 2 2 0 IncA protein Daxx PF03344.10 EIW71542.1 - 1.2 7.5 12.3 1.3 7.4 8.5 1.1 1 0 0 1 1 1 0 Daxx Family DNA_pol_phi PF04931.8 EIW71542.1 - 3 5.5 8.9 4 5.0 6.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Dus PF01207.12 EIW71544.1 - 6.3e-48 163.1 0.0 1.2e-47 162.3 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PspA_IM30 PF04012.7 EIW71544.1 - 0.059 12.7 0.5 0.1 11.9 0.3 1.3 1 0 0 1 1 1 0 PspA/IM30 family Mak10 PF04112.8 EIW71545.1 - 7.9e-20 70.7 0.0 1.4e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase LEA_2 PF03168.8 EIW71546.1 - 3.3e-05 24.1 0.0 6.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.7 EIW71546.1 - 0.032 13.4 0.6 0.035 13.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) RRM_1 PF00076.17 EIW71547.1 - 2.3e-23 81.6 0.0 3.1e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW71547.1 - 1e-16 60.6 0.0 1.3e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW71547.1 - 4e-12 45.7 0.0 5.5e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2263 PF10021.4 EIW71547.1 - 0.36 10.8 0.1 0.36 10.8 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2263) Ribosomal_L24e PF01246.15 EIW71548.1 - 6.8e-30 102.7 0.8 2.3e-29 101.0 0.5 2.0 1 0 0 1 1 1 1 Ribosomal protein L24e DUF4078 PF13300.1 EIW71548.1 - 2.7e-15 56.2 9.6 2.7e-15 56.2 6.6 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF4078) DUF947 PF06102.7 EIW71549.1 - 3.8e-43 147.2 16.7 3.8e-43 147.2 11.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF947) Myb_DNA-bind_5 PF13873.1 EIW71549.1 - 0.019 14.8 2.4 0.019 14.8 1.6 3.3 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain SWIB PF02201.13 EIW71550.1 - 0.00075 19.1 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain EMP24_GP25L PF01105.19 EIW71551.1 - 3.9e-46 157.0 0.2 4.3e-46 156.9 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD V-SNARE_C PF12352.3 EIW71552.1 - 1.5e-15 56.9 0.7 1.5e-15 56.9 0.5 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EIW71552.1 - 0.062 13.0 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Sec20 Peptidase_M24 PF00557.19 EIW71553.1 - 3e-43 147.8 0.0 4.3e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2034 PF10356.4 EIW71554.1 - 8.3e-35 119.6 0.0 1.1e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EIW71554.1 - 1.1e-07 31.6 0.0 4.1e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Restriction endonuclease Methyltransf_15 PF09445.5 EIW71555.1 - 9.6e-33 113.0 0.0 2.8e-32 111.5 0.0 1.7 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EIW71555.1 - 2.4e-08 34.0 0.0 4.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EIW71555.1 - 1.9e-07 30.8 0.0 4.4e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 EIW71555.1 - 6.4e-07 29.9 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW71555.1 - 7.8e-07 28.7 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EIW71555.1 - 1.7e-05 24.3 0.0 2.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.11 EIW71555.1 - 1.7e-05 24.5 0.0 3.6e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_25 PF13649.1 EIW71555.1 - 0.00055 20.2 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EIW71555.1 - 0.025 13.6 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pkinase PF00069.20 EIW71556.1 - 1.1e-72 244.3 0.0 1.2e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71556.1 - 1.5e-52 178.2 0.0 1.8e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW71556.1 - 5.6e-05 22.2 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Serinc PF03348.10 EIW71557.1 - 5.9e-153 509.5 0.9 7.6e-153 509.2 0.6 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) DEAD PF00270.24 EIW71559.1 - 8.8e-45 152.2 0.0 9.7e-44 148.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW71559.1 - 8.7e-26 89.5 0.0 2.6e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EIW71559.1 - 0.00089 17.7 0.0 1.3 7.3 0.0 3.5 2 1 1 3 3 3 2 Protein of unknown function (DUF1253) ResIII PF04851.10 EIW71559.1 - 0.0024 17.7 6.6 0.0046 16.8 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Daxx PF03344.10 EIW71559.1 - 0.0024 16.4 20.6 0.0024 16.4 14.3 2.1 2 0 0 2 2 2 1 Daxx Family AAA_22 PF13401.1 EIW71559.1 - 0.0092 16.1 0.1 0.054 13.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain Polyketide_cyc PF03364.15 EIW71560.1 - 6.7e-17 61.7 0.0 8.8e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport UCH PF00443.24 EIW71561.1 - 4.7e-63 212.8 0.0 1.2e-62 211.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW71561.1 - 9.3e-37 127.0 0.3 2.5e-27 96.1 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EIW71561.1 - 0.009 15.3 4.7 0.76 9.0 2.2 2.9 3 1 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF972 PF06156.8 EIW71562.1 - 0.005 17.1 1.2 0.039 14.3 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.7 EIW71562.1 - 0.15 11.8 1.0 0.73 9.6 0.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PRCC PF10253.4 EIW71563.1 - 0.23 12.1 2.7 0.27 11.8 1.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting WD40 PF00400.27 EIW71564.1 - 1e-35 120.3 11.9 1.4e-08 34.3 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EIW71564.1 - 2.6e-30 104.1 0.5 6e-30 102.9 0.3 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 EIW71564.1 - 0.11 11.2 0.0 0.27 9.9 0.0 1.5 1 1 0 1 1 1 0 Nup133 N terminal like Y_phosphatase2 PF03162.8 EIW71565.1 - 4.4e-58 195.2 0.0 5.6e-58 194.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EIW71565.1 - 1.3e-06 28.7 0.0 2.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EIW71565.1 - 4.9e-05 22.9 0.0 7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW71565.1 - 0.00064 19.1 0.0 0.0008 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3074 PF11274.3 EIW71566.1 - 2.6e-42 144.5 0.0 1.2e-41 142.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) FKBP_C PF00254.23 EIW71567.1 - 1.7e-33 114.4 0.0 2.1e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase VWA_2 PF13519.1 EIW71568.1 - 0.00025 21.1 0.0 0.00042 20.4 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EIW71568.1 - 0.0026 17.5 0.0 0.006 16.3 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Sushi PF00084.15 EIW71570.1 - 0.082 13.2 1.0 0.4 11.0 0.2 2.3 2 0 0 2 2 2 0 Sushi domain (SCR repeat) DEC-1_N PF04625.8 EIW71570.1 - 0.26 9.9 10.0 0.34 9.5 6.9 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PrmA PF06325.8 EIW71571.1 - 9.5e-11 41.3 0.3 1.9e-10 40.3 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EIW71571.1 - 1.1e-09 38.0 0.0 2.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW71571.1 - 1.6e-09 38.3 0.0 3.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW71571.1 - 9.6e-09 35.2 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW71571.1 - 1.5e-06 27.6 0.0 2.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EIW71571.1 - 3.2e-06 27.5 0.0 9.2e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EIW71571.1 - 1.1e-05 24.6 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 EIW71571.1 - 2.2e-05 24.2 0.0 5.9e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EIW71571.1 - 4.4e-05 22.6 0.0 7.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EIW71571.1 - 6.2e-05 23.3 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW71571.1 - 0.00039 20.0 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 EIW71571.1 - 0.00096 18.7 0.1 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_9 PF08003.6 EIW71571.1 - 0.0067 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 EIW71571.1 - 0.011 16.1 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EIW71571.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EIW71571.1 - 0.022 14.1 0.0 0.047 13.0 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 EIW71571.1 - 0.096 13.5 0.0 0.23 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Acetyltransf_7 PF13508.1 EIW71572.1 - 0.0017 18.4 0.0 0.06 13.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW71572.1 - 0.038 14.0 0.1 0.15 12.1 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family G-patch PF01585.18 EIW71573.1 - 5.6e-16 58.0 0.6 1.1e-15 57.0 0.4 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIW71573.1 - 1.9e-07 30.7 1.1 1.9e-07 30.7 0.8 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site FHA PF00498.21 EIW71573.1 - 5e-05 23.3 0.0 0.00012 22.1 0.0 1.7 1 1 0 1 1 1 1 FHA domain Mito_carr PF00153.22 EIW71574.1 - 2.8e-68 225.6 1.3 2.4e-22 78.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.17 EIW71575.1 - 1.6e-53 180.4 0.0 1.9e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW71575.1 - 1.9e-18 67.1 0.0 2.7e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW71575.1 - 3.4e-12 45.9 0.0 4.2e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW71575.1 - 1.1e-05 24.6 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW71575.1 - 4.5e-05 22.9 0.0 0.0005 19.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW71575.1 - 0.00087 19.2 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIW71575.1 - 0.0043 17.1 0.0 0.014 15.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EIW71575.1 - 0.0044 16.5 0.0 0.09 12.2 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EIW71575.1 - 0.012 15.6 0.1 0.021 14.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.4 EIW71575.1 - 0.024 13.5 0.0 0.049 12.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.5 EIW71575.1 - 0.033 13.3 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2075 PF09848.4 EIW71575.1 - 0.04 12.8 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EIW71575.1 - 0.077 11.8 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Methyltransf_25 PF13649.1 EIW71575.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain NACHT PF05729.7 EIW71575.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DNA_primase_S PF01896.14 EIW71576.1 - 4.8e-53 178.8 0.2 7.1e-53 178.3 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit ATP-synt_E PF05680.7 EIW71577.1 - 1.5e-18 66.4 0.4 1.6e-18 66.3 0.3 1.1 1 0 0 1 1 1 1 ATP synthase E chain Adaptin_N PF01602.15 EIW71578.1 - 7.8e-92 308.2 3.0 7.8e-92 308.2 2.1 1.6 2 0 0 2 2 2 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 EIW71578.1 - 9.1e-61 203.6 0.4 5.1e-60 201.2 0.2 2.3 2 0 0 2 2 2 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 EIW71578.1 - 7.1e-55 184.2 0.1 2.9e-54 182.2 0.0 2.1 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 EIW71578.1 - 3.2e-10 40.1 1.7 0.016 15.4 0.0 4.2 2 1 1 3 3 3 3 HEAT repeats Cnd1 PF12717.2 EIW71578.1 - 2.3e-09 37.3 1.5 0.016 15.0 0.0 4.7 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EIW71578.1 - 4.4e-06 26.3 0.3 0.59 10.3 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EIW71578.1 - 0.015 15.7 0.0 40 4.8 0.0 4.4 3 1 1 4 4 4 0 HEAT-like repeat ParcG PF10274.4 EIW71578.1 - 0.015 15.2 1.6 1.9 8.3 0.0 2.9 2 0 0 2 2 2 0 Parkin co-regulated protein BCS1_N PF08740.6 EIW71579.1 - 1.6e-54 184.4 0.5 2.2e-54 183.9 0.4 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIW71579.1 - 1.2e-18 67.6 0.0 1.9e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW71579.1 - 5.5e-05 23.9 0.0 0.00011 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW71579.1 - 0.00045 20.1 0.0 0.00088 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW71579.1 - 0.003 17.2 0.0 0.01 15.5 0.0 1.9 1 1 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EIW71579.1 - 0.0034 16.7 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW71579.1 - 0.0056 16.6 0.1 0.017 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EIW71579.1 - 0.0099 15.6 0.0 0.022 14.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EIW71579.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW71579.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIW71579.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW71579.1 - 0.027 13.9 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 EIW71579.1 - 0.031 13.2 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.7 EIW71579.1 - 0.043 12.8 0.1 0.096 11.7 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.1 EIW71579.1 - 0.053 13.0 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW71579.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EIW71579.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain P33MONOX PF15302.1 EIW71579.1 - 0.097 12.2 0.5 0.15 11.6 0.4 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase AAA_21 PF13304.1 EIW71579.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EIW71579.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 EIW71579.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 EIW71579.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Polyoma_lg_T_C PF06431.6 EIW71579.1 - 0.18 10.3 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Glyco_trans_1_2 PF13524.1 EIW71580.1 - 0.015 15.5 0.6 0.073 13.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 Brix PF04427.13 EIW71581.1 - 2.6e-35 121.8 0.0 3.2e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF3584 PF12128.3 EIW71582.1 - 0.28 8.4 46.2 0.41 7.9 32.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2404 PF10296.4 EIW71583.1 - 0.041 14.0 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) GRASP55_65 PF04495.9 EIW71584.1 - 1.4e-53 180.5 0.0 4.5e-44 149.8 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.1 EIW71584.1 - 0.0059 16.3 0.0 0.053 13.3 0.0 2.2 2 0 0 2 2 2 1 Tricorn protease PDZ domain PDZ_2 PF13180.1 EIW71584.1 - 0.0059 16.4 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 PDZ domain DUF3419 PF11899.3 EIW71585.1 - 3.7e-142 473.5 0.0 5.8e-142 472.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_18 PF12847.2 EIW71585.1 - 0.00059 20.3 0.0 0.0017 18.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW71585.1 - 0.0011 19.4 0.0 0.15 12.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW71585.1 - 0.0016 17.5 0.0 0.073 12.1 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIW71585.1 - 0.0028 17.2 0.0 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW71585.1 - 0.03 14.0 0.0 0.12 12.0 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIW71585.1 - 0.097 13.1 0.0 0.89 10.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EIW71585.1 - 0.15 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EIW71585.1 - 0.15 12.0 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Ras PF00071.17 EIW71586.1 - 7.7e-63 210.7 0.3 9e-63 210.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW71586.1 - 2.2e-21 76.5 0.0 3.1e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW71586.1 - 4.2e-13 48.9 0.1 5.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIW71586.1 - 4.6e-08 33.0 0.1 7.9e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW71586.1 - 9.8e-06 25.1 0.2 2.7e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EIW71586.1 - 2.8e-05 24.2 0.2 0.00012 22.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 EIW71586.1 - 0.00043 19.4 0.1 0.00076 18.6 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EIW71586.1 - 0.0019 17.3 0.0 0.0026 16.8 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EIW71586.1 - 0.0028 16.8 0.0 0.007 15.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EIW71586.1 - 0.0049 16.0 0.0 0.01 15.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EIW71586.1 - 0.0064 16.3 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EIW71586.1 - 0.015 14.7 0.0 0.057 12.8 0.0 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EIW71586.1 - 0.023 15.0 0.1 0.033 14.4 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EIW71586.1 - 0.027 14.4 0.2 0.064 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EIW71586.1 - 0.036 13.3 0.4 0.14 11.4 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF1128 PF06569.6 EIW71586.1 - 0.075 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) AAA_5 PF07728.9 EIW71586.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_32 PF13654.1 EIW71586.1 - 0.11 11.0 0.1 1.4 7.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 EIW71586.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF572 PF04502.8 EIW71587.1 - 1e-53 182.7 0.0 1.1e-53 182.5 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Steroid_dh PF02544.11 EIW71588.1 - 4.6e-17 62.1 1.7 7.5e-17 61.4 1.2 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 EIW71588.1 - 0.13 11.6 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family Ribosomal_L2_C PF03947.13 EIW71589.1 - 1.8e-44 150.6 4.1 4e-44 149.5 2.9 1.6 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EIW71589.1 - 3.9e-21 74.8 0.4 8.2e-21 73.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain UAA PF08449.6 EIW71590.1 - 8.3e-68 228.5 3.6 1.1e-67 228.1 2.5 1.1 1 0 0 1 1 1 1 UAA transporter family HMA PF00403.21 EIW71591.1 - 5e-11 42.5 0.1 1.4e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Heavy-metal-associated domain FlxA PF14282.1 EIW71592.1 - 0.0054 16.6 4.5 0.0054 16.6 3.1 3.6 2 1 1 3 3 3 1 FlxA-like protein UCH PF00443.24 EIW71593.1 - 0.00011 21.3 0.0 0.00055 19.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW71593.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TPP1 PF10341.4 EIW71594.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD AIRC PF00731.15 EIW71595.1 - 2.5e-64 215.1 2.4 2.5e-64 215.0 0.8 1.7 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.17 EIW71595.1 - 3.6e-52 176.1 0.0 7.1e-52 175.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EIW71595.1 - 1.3e-09 38.1 0.2 1.2e-08 34.8 0.1 2.2 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIW71595.1 - 4e-05 23.1 0.0 0.014 14.7 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EIW71595.1 - 0.0057 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIW71595.1 - 0.0061 15.3 0.0 1.2 7.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EIW71595.1 - 0.013 14.8 0.0 0.086 12.1 0.0 2.1 2 1 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PrpR_N PF06506.6 EIW71595.1 - 0.031 13.6 0.3 0.24 10.7 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator CoA_binding_2 PF13380.1 EIW71595.1 - 0.11 12.6 0.7 59 3.8 0.1 3.8 3 1 1 4 4 4 0 CoA binding domain Sel1 PF08238.7 EIW71596.1 - 1.3e-46 155.9 20.4 2.9e-09 37.2 0.3 7.7 8 0 0 8 8 8 7 Sel1 repeat Glyco_trans_1_4 PF13692.1 EIW71596.1 - 0.013 15.6 0.2 0.044 13.9 0.1 1.9 1 1 1 2 2 2 0 Glycosyl transferases group 1 TPR_5 PF12688.2 EIW71596.1 - 0.056 13.4 1.0 0.92 9.5 0.0 2.9 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_16 PF13432.1 EIW71596.1 - 0.25 12.0 16.9 1 10.1 0.7 5.0 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW71596.1 - 1.2 9.6 12.3 21 5.8 0.1 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat ABC_tran PF00005.22 EIW71597.1 - 4.9e-51 172.6 0.3 2.2e-28 99.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EIW71597.1 - 1.1e-39 136.4 14.4 4.2e-26 91.9 2.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EIW71597.1 - 4e-09 36.8 0.4 0.0071 16.3 0.0 4.2 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW71597.1 - 8.1e-09 35.7 2.8 0.002 18.1 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EIW71597.1 - 6.7e-07 29.2 0.1 0.029 14.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EIW71597.1 - 3.6e-06 26.5 0.0 0.073 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW71597.1 - 5.6e-06 26.5 0.2 0.029 14.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 EIW71597.1 - 4.1e-05 23.1 0.2 0.26 10.7 0.0 3.1 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain SMC_N PF02463.14 EIW71597.1 - 4.6e-05 22.7 1.5 0.28 10.3 0.0 3.7 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EIW71597.1 - 7.7e-05 23.5 0.0 0.081 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIW71597.1 - 0.00012 21.2 0.0 0.51 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIW71597.1 - 0.0002 20.8 0.3 0.31 10.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EIW71597.1 - 0.00037 20.9 0.9 0.58 10.6 0.2 2.7 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 EIW71597.1 - 0.0004 20.0 0.3 0.094 12.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 EIW71597.1 - 0.0021 17.2 0.7 0.096 11.7 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 EIW71597.1 - 0.0022 17.7 1.4 0.42 10.3 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EIW71597.1 - 0.0028 17.5 0.1 0.58 10.1 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EIW71597.1 - 0.003 17.1 1.6 1.7 8.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EIW71597.1 - 0.0033 16.8 0.0 1.3 8.3 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EIW71597.1 - 0.0041 17.2 0.0 2.8 8.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 EIW71597.1 - 0.0068 15.8 0.0 3.7 6.9 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EIW71597.1 - 0.007 16.7 0.0 0.73 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 EIW71597.1 - 0.0094 14.6 0.4 0.26 9.8 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EIW71597.1 - 0.0097 16.2 0.0 1.8 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EIW71597.1 - 0.0097 14.7 0.9 1.3 7.8 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.8 EIW71597.1 - 0.017 14.0 0.1 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.24 EIW71597.1 - 0.021 15.0 0.0 14 5.8 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EIW71597.1 - 0.029 14.0 1.3 2 8.0 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EIW71597.1 - 0.037 13.7 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase DUF87 PF01935.12 EIW71597.1 - 0.037 13.8 4.9 0.4 10.4 0.4 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 ArgK PF03308.11 EIW71597.1 - 0.04 12.6 1.2 1.2 7.8 0.1 2.3 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EIW71597.1 - 0.058 13.2 0.2 4.9 6.9 0.1 2.6 2 0 0 2 2 2 0 Dynamin family ABC_ATPase PF09818.4 EIW71597.1 - 0.06 11.9 0.5 15 3.9 0.0 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Sigma54_activat PF00158.21 EIW71597.1 - 0.064 12.7 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_10 PF12846.2 EIW71597.1 - 0.13 11.6 1.0 3.7 6.9 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 EIW71597.1 - 0.18 11.2 1.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain La PF05383.12 EIW71598.1 - 1.2e-16 60.2 0.0 2.1e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EIW71598.1 - 0.0038 16.8 1.8 0.019 14.5 0.4 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kelch_5 PF13854.1 EIW71599.1 - 2.1e-14 53.1 1.9 0.00025 20.8 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 EIW71599.1 - 2.8e-12 46.1 19.2 0.00023 20.8 0.1 6.3 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EIW71599.1 - 3.1e-05 23.9 7.8 0.3 11.3 0.0 5.2 4 1 1 5 5 5 2 Kelch motif SKG6 PF08693.5 EIW71599.1 - 0.0014 17.8 0.0 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_2 PF07646.10 EIW71599.1 - 0.18 11.6 6.5 6.6 6.6 0.1 4.6 5 0 0 5 5 5 0 Kelch motif Kelch_1 PF01344.20 EIW71599.1 - 0.27 10.8 5.1 25 4.5 0.0 4.6 5 0 0 5 5 5 0 Kelch motif MFS_1 PF07690.11 EIW71600.1 - 4.3e-33 114.4 38.8 2.5e-26 92.2 8.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.18 EIW71601.1 - 3.8e-32 111.9 0.0 7e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EIW71601.1 - 2.8e-05 23.4 0.0 4.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EIW71601.1 - 0.028 13.0 0.3 0.17 10.4 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EIW71601.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L3 PF00297.17 EIW71602.1 - 1.5e-36 126.1 0.0 2.7e-34 118.7 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 PIF1 PF05970.9 EIW71604.1 - 7.9e-06 25.0 0.0 1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 EIW71604.1 - 0.0025 17.5 0.0 0.0072 16.0 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EIW71604.1 - 0.17 11.4 0.1 0.54 9.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain Tet_JBP PF12851.2 EIW71605.1 - 6.5e-05 22.2 0.0 0.00016 21.0 0.0 1.6 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EIW71605.1 - 0.0041 17.6 1.2 0.015 15.8 0.1 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF498 PF04430.9 EIW71606.1 - 1.8e-16 59.6 0.0 2.4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) ABC_membrane PF00664.18 EIW71607.1 - 9.4e-47 159.7 24.6 1.6e-29 103.1 2.9 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW71607.1 - 6.9e-44 149.4 0.0 2.6e-26 92.5 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW71607.1 - 6.1e-07 29.6 0.1 0.006 16.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EIW71607.1 - 1.8e-06 28.0 0.2 0.053 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EIW71607.1 - 2.6e-05 23.5 0.0 0.063 12.4 0.0 3.4 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW71607.1 - 3.6e-05 23.2 0.0 0.033 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW71607.1 - 0.00013 22.0 0.8 1.2 9.3 0.2 3.4 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EIW71607.1 - 0.00019 21.3 0.6 0.16 11.9 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIW71607.1 - 0.00072 20.0 0.6 1.6 9.2 0.1 2.8 2 0 0 2 2 2 2 Miro-like protein ATP-synt_ab PF00006.20 EIW71607.1 - 0.00096 18.7 0.4 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 EIW71607.1 - 0.0012 19.6 0.4 0.062 14.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EIW71607.1 - 0.0015 18.7 0.5 4.9 7.3 0.0 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EIW71607.1 - 0.0038 16.8 0.2 0.18 11.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 EIW71607.1 - 0.0053 15.8 0.8 0.88 8.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.1 EIW71607.1 - 0.007 16.2 0.9 0.34 10.8 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EIW71607.1 - 0.0082 15.9 0.2 0.27 11.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 EIW71607.1 - 0.0092 15.6 0.2 1.1 8.9 0.1 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EIW71607.1 - 0.01 15.3 0.1 0.51 9.9 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 EIW71607.1 - 0.019 14.1 0.2 6.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Pox_A32 PF04665.7 EIW71607.1 - 0.023 13.9 0.1 0.33 10.2 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_30 PF13604.1 EIW71607.1 - 0.026 14.1 0.7 4.8 6.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 EIW71607.1 - 0.032 12.8 1.4 0.37 9.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 EIW71607.1 - 0.038 12.9 0.2 0.71 8.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 EIW71607.1 - 0.047 12.6 0.3 0.82 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EIW71607.1 - 0.051 12.4 1.2 5.7 5.7 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.21 EIW71607.1 - 0.06 12.8 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EIW71607.1 - 0.078 12.3 0.0 4 6.8 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SE PF00437.15 EIW71607.1 - 0.08 11.8 0.0 2.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.1 EIW71607.1 - 0.11 12.7 0.3 2.6 8.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EIW71607.1 - 0.12 12.0 0.0 0.36 10.4 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EIW71607.1 - 0.14 11.6 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 EIW71607.1 - 0.16 11.6 1.8 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EIW71607.1 - 0.2 11.0 0.4 0.56 9.6 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EIW71607.1 - 0.32 11.2 2.9 0.71 10.1 0.1 2.5 3 0 0 3 3 2 0 AAA domain Abhydrolase_3 PF07859.8 EIW71609.1 - 8e-09 35.3 0.6 2.2e-07 30.6 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold CbiX PF01903.12 EIW71609.1 - 0.0031 17.5 0.1 0.49 10.5 0.0 2.2 2 0 0 2 2 2 2 CbiX COesterase PF00135.23 EIW71609.1 - 0.025 13.3 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family PfkB PF00294.19 EIW71611.1 - 9.4e-21 74.2 0.0 1.1e-12 47.7 0.0 2.0 2 0 0 2 2 2 2 pfkB family carbohydrate kinase PI-PLC-X PF00388.14 EIW71612.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain UPF0542 PF15086.1 EIW71612.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF676 PF05057.9 EIW71613.1 - 3.2e-05 23.3 0.0 8.8e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EIW71613.1 - 0.016 14.8 0.1 0.045 13.3 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein DUF2428 PF10350.4 EIW71615.1 - 1.5e-45 155.2 0.0 3.1e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EIW71615.1 - 7.5e-07 28.7 0.1 4.5 7.6 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EIW71615.1 - 0.0026 17.9 7.4 19 5.5 0.0 6.2 6 2 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 EIW71615.1 - 0.019 15.4 5.9 2 9.0 0.0 5.8 8 0 0 8 8 8 0 HEAT-like repeat HA2 PF04408.18 EIW71616.1 - 4.5e-26 90.8 0.0 1.5e-25 89.1 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIW71616.1 - 4.4e-13 48.8 0.0 1.1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EIW71616.1 - 5.4e-12 45.5 0.0 1.3e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EIW71616.1 - 5.8e-08 32.4 0.0 1.9e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIW71616.1 - 6.6e-06 26.2 0.1 1.6e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EIW71616.1 - 0.0021 17.9 0.3 1.4 8.6 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_14 PF13173.1 EIW71616.1 - 0.0038 17.1 0.1 0.022 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EIW71616.1 - 0.0038 16.1 0.0 0.0076 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EIW71616.1 - 0.0042 16.6 0.2 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EIW71616.1 - 0.0079 15.2 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EIW71616.1 - 0.015 14.1 0.1 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 EIW71616.1 - 0.018 14.4 0.1 5.6 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EIW71616.1 - 0.028 13.8 0.0 8.7 5.7 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.22 EIW71616.1 - 0.038 14.3 0.0 0.25 11.6 0.0 2.1 1 1 0 2 2 2 0 ABC transporter NACHT PF05729.7 EIW71616.1 - 0.064 12.9 0.2 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.17 EIW71616.1 - 0.095 12.1 0.2 0.28 10.5 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain KaiC PF06745.8 EIW71616.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 KaiC MFS_1 PF07690.11 EIW71617.1 - 1.7e-39 135.5 33.6 1.6e-27 96.1 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW71617.1 - 6.2e-07 28.1 12.3 0.00066 18.1 1.9 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EIW71617.1 - 0.017 14.9 8.0 0.035 13.9 0.0 3.9 4 0 0 4 4 4 0 MFS_1 like family Patched PF02460.13 EIW71618.1 - 3.2e-76 256.8 2.6 2.6e-39 134.8 0.1 3.3 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.3 EIW71618.1 - 2.7e-46 156.8 11.2 8.2e-24 83.8 0.2 3.6 3 0 0 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EIW71618.1 - 2.9e-08 31.6 1.6 5.5e-08 30.7 1.1 1.4 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF1700 PF08006.6 EIW71618.1 - 7.3 5.8 16.5 0.5 9.6 1.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) zf-CCHC PF00098.18 EIW71620.1 - 0.0025 17.6 1.9 0.0044 16.8 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW71620.1 - 0.06 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 EIW71621.1 - 5.3e-22 78.2 0.1 1.9e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIW71621.1 - 1.3e-18 67.2 0.0 4e-18 65.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIW71621.1 - 3.3e-08 33.0 0.1 1e-07 31.5 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3818 PF12825.2 EIW71621.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Cpn10 PF00166.16 EIW71623.1 - 0.1 12.5 0.0 0.67 9.9 0.0 2.3 3 0 0 3 3 3 0 Chaperonin 10 Kd subunit E1_dh PF00676.15 EIW71626.1 - 2.9e-86 288.9 0.0 3.4e-86 288.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_15 PF00723.16 EIW71627.1 - 3.2e-52 177.5 0.0 4.1e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Peptidase_M14 PF00246.19 EIW71628.1 - 1.2e-61 208.8 0.0 1.6e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase RAP1 PF07218.6 EIW71630.1 - 6.1 4.7 6.6 6.7 4.6 4.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CAP PF00188.21 EIW71631.1 - 3.5e-23 82.4 0.9 6.2e-23 81.6 0.6 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF1381 PF07129.6 EIW71631.1 - 0.079 12.3 1.5 3.5 7.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1381) ICAP-1_inte_bdg PF10480.4 EIW71631.1 - 0.27 11.0 3.9 0.42 10.3 2.7 1.3 1 0 0 1 1 1 0 Beta-1 integrin binding protein SH3_1 PF00018.23 EIW71632.1 - 1.7e-05 24.1 0.0 3.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SDA1 PF05285.7 EIW71632.1 - 8e-05 22.0 9.3 0.00012 21.4 6.4 1.3 1 0 0 1 1 1 1 SDA1 SH3_9 PF14604.1 EIW71632.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SynMuv_product PF06047.6 EIW71634.1 - 5.1e-44 148.3 2.7 6.5e-44 147.9 1.9 1.1 1 0 0 1 1 1 1 Ras-induced vulval development antagonist FliX PF10768.4 EIW71635.1 - 0.4 10.8 4.7 0.17 12.1 0.4 2.0 2 0 0 2 2 2 0 Class II flagellar assembly regulator CAP PF00188.21 EIW71636.1 - 4e-21 75.7 2.2 8e-21 74.8 1.5 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Zn_clus PF00172.13 EIW71637.1 - 0.015 15.1 5.2 0.027 14.3 3.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1168 PF06658.7 EIW71638.1 - 7.6e-38 129.2 15.7 1.3e-37 128.5 10.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) Orthopox_C10L PF07020.6 EIW71638.1 - 0.018 15.5 1.5 0.053 14.0 0.3 2.0 2 0 0 2 2 2 0 Orthopoxvirus C10L protein MelC1 PF06236.6 EIW71638.1 - 0.14 12.1 2.0 0.26 11.2 1.4 1.4 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 NARP1 PF12569.3 EIW71638.1 - 2.5 6.7 10.2 3.9 6.0 7.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DLH PF01738.13 EIW71639.1 - 4.7e-14 52.1 0.0 6.3e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW71639.1 - 1.9e-06 27.6 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Proteasom_Rpn13 PF04683.8 EIW71640.1 - 2.5e-22 78.7 0.0 3.6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor UPRTase PF14681.1 EIW71641.1 - 1.4e-61 207.2 0.0 3.8e-46 156.9 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EIW71641.1 - 7.2e-06 25.7 0.0 9.6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MFS_1 PF07690.11 EIW71642.1 - 8.5e-42 143.1 35.3 1.4e-41 142.4 24.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW71642.1 - 1.1e-07 30.8 9.4 1.1e-07 30.8 6.5 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter DUF872 PF05915.7 EIW71642.1 - 1.8 8.4 4.2 0.88 9.4 0.7 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF89 PF01937.14 EIW71643.1 - 6.3e-109 364.0 0.1 7.2e-109 363.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Ribosomal_S4 PF00163.14 EIW71646.1 - 1.1e-26 93.0 3.1 2.1e-26 92.1 2.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EIW71646.1 - 6.6e-12 44.6 1.8 6.6e-12 44.6 1.2 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EIW71647.1 - 5.5e-36 122.3 4.4 9e-36 121.6 2.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.4 EIW71647.1 - 0.052 12.9 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Pyr_redox_2 PF07992.9 EIW71648.1 - 2.2e-41 141.9 0.2 3.7e-41 141.2 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EIW71648.1 - 1.3e-34 118.5 0.1 7e-34 116.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EIW71648.1 - 6.6e-21 74.5 2.3 1.2e-17 64.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW71648.1 - 2.5e-13 50.5 0.3 8.4e-10 39.0 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW71648.1 - 2.7e-08 33.3 0.1 5e-08 32.4 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW71648.1 - 8.3e-06 24.5 1.6 0.0048 15.4 0.4 2.9 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 EIW71648.1 - 8.9e-06 24.8 0.8 0.00063 18.7 1.0 3.1 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EIW71648.1 - 1.1e-05 24.5 6.6 0.0027 16.5 2.1 2.4 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 EIW71648.1 - 0.00021 20.3 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIW71648.1 - 0.00028 20.8 2.3 0.00073 19.5 1.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW71648.1 - 0.001 18.0 1.4 0.001 18.0 1.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIW71648.1 - 0.0032 16.6 1.2 0.0049 15.9 0.2 1.7 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 EIW71648.1 - 0.013 15.1 0.1 0.95 9.0 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EIW71648.1 - 0.015 14.4 0.4 1.4 8.0 0.0 3.1 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIW71648.1 - 0.033 13.8 0.0 0.033 13.8 0.0 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EIW71648.1 - 0.087 13.0 0.4 1.4 9.2 0.1 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EIW71648.1 - 0.13 11.2 1.3 3.5 6.5 0.3 2.5 2 0 0 2 2 2 0 FAD binding domain RhoGEF PF00621.15 EIW71649.1 - 1.2e-05 25.3 0.0 0.0001 22.2 0.0 2.3 2 0 0 2 2 2 1 RhoGEF domain TraG-D_C PF12696.2 EIW71649.1 - 0.19 11.6 1.3 1.4 8.8 0.0 2.6 2 1 0 2 2 2 0 TraM recognition site of TraD and TraG DASH_Dam1 PF08653.5 EIW71650.1 - 4.9e-23 80.6 0.6 6.2e-23 80.3 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 HpcH_HpaI PF03328.9 EIW71650.1 - 0.083 11.7 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family CDC73 PF05179.9 EIW71651.1 - 1e-53 182.5 1.8 1.4e-53 182.0 1.3 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family DNA_ligase_A_M PF01068.16 EIW71652.1 - 3.7e-19 68.8 0.0 8.5e-19 67.7 0.0 1.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIW71652.1 - 3.7e-06 26.8 0.0 6.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DUF2587 PF10759.4 EIW71655.1 - 0.041 13.2 0.1 0.11 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) SR-25 PF10500.4 EIW71655.1 - 0.93 8.9 33.4 0.11 11.9 13.1 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_L7Ae PF01248.21 EIW71656.1 - 2.2e-19 68.7 0.6 2.5e-19 68.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EIW71656.1 - 0.03 14.1 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 Aldedh PF00171.17 EIW71657.1 - 4.1e-118 394.6 0.2 2.4e-113 378.9 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 EIW71657.1 - 1.4e-05 23.9 0.0 2.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Syja_N PF02383.13 EIW71658.1 - 6.8e-87 291.1 0.0 1.1e-86 290.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain NUC173 PF08161.7 EIW71658.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 NUC173 domain Arrestin_C PF02752.17 EIW71659.1 - 3e-16 59.7 0.0 1.3e-14 54.4 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIW71659.1 - 6.7e-10 38.9 0.6 2.3e-09 37.2 0.0 2.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EIW71659.1 - 0.0034 16.8 0.0 0.008 15.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like UCH PF00443.24 EIW71661.1 - 0.00043 19.4 0.0 0.014 14.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Tet_JBP PF12851.2 EIW71662.1 - 0.021 14.1 0.0 0.046 13.0 0.0 1.8 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Helicase_C PF00271.26 EIW71664.1 - 6e-10 38.8 0.0 3.1e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW71664.1 - 8.4e-10 38.3 0.0 2.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 EIW71664.1 - 3.7e-05 23.3 0.0 0.0001 22.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Helicase_RecD PF05127.9 EIW71664.1 - 0.0029 17.2 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.1 EIW71664.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIW71664.1 - 0.005 16.2 0.0 0.017 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Yeast-kill-tox PF09207.6 EIW71664.1 - 0.12 12.8 0.1 0.4 11.1 0.0 1.9 2 0 0 2 2 2 0 Yeast killer toxin T2SE PF00437.15 EIW71664.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UPRTase PF14681.1 EIW71665.1 - 2.6e-63 212.9 0.0 3e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EIW71665.1 - 0.068 12.9 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain CK_II_beta PF01214.13 EIW71666.1 - 9.1e-74 246.9 0.0 1.1e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Sec1 PF00995.18 EIW71667.1 - 1.2e-122 410.4 0.0 2.1e-122 409.6 0.0 1.4 2 0 0 2 2 2 1 Sec1 family Spc97_Spc98 PF04130.8 EIW71668.1 - 3.1e-70 237.0 1.7 3.5e-70 236.8 0.4 1.6 2 0 0 2 2 2 1 Spc97 / Spc98 family Nup88 PF10168.4 EIW71669.1 - 1.5e-19 69.3 0.7 4.9e-11 41.2 0.0 2.3 2 0 0 2 2 2 2 Nuclear pore component L27_1 PF09058.5 EIW71669.1 - 0.091 12.6 1.8 0.37 10.6 1.2 2.1 1 0 0 1 1 1 0 L27_1 Syntaxin_2 PF14523.1 EIW71669.1 - 0.51 10.4 5.0 0.21 11.6 1.4 2.0 2 0 0 2 2 2 0 Syntaxin-like protein Noelin-1 PF12308.3 EIW71669.1 - 4.7 7.0 7.6 0.38 10.5 0.2 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein MoCF_biosynth PF00994.19 EIW71670.1 - 1.6e-31 108.6 0.0 2.9e-31 107.8 0.0 1.5 1 1 0 1 1 1 1 Probable molybdopterin binding domain Aminotran_1_2 PF00155.16 EIW71671.1 - 2e-23 82.9 0.0 2.2e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II UDPGT PF00201.13 EIW71673.1 - 2.9e-16 59.1 0.1 4.1e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase F-box-like PF12937.2 EIW71674.1 - 6e-07 29.0 0.0 1.4e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EIW71674.1 - 4.5e-05 23.1 0.7 0.00023 20.9 0.1 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Ribosomal_S25 PF03297.10 EIW71675.1 - 8.7e-45 151.0 1.8 9.6e-45 150.9 1.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 EIW71675.1 - 0.0098 15.5 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 MarR family Ftsk_gamma PF09397.5 EIW71675.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Ftsk gamma domain HTH_DeoR PF08220.7 EIW71675.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.7 EIW71675.1 - 0.059 13.0 0.1 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 HTH domain GntR PF00392.16 EIW71675.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_24 PF13412.1 EIW71675.1 - 0.1 11.9 0.2 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ParA PF10609.4 EIW71676.1 - 1.2e-31 108.3 0.1 2.2e-31 107.5 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIW71676.1 - 9.6e-16 57.7 0.0 1.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIW71676.1 - 3.3e-07 30.3 0.1 3.2e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EIW71676.1 - 1.6e-05 24.1 0.3 3.2e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.1 EIW71676.1 - 0.00011 21.6 0.1 0.00021 20.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EIW71676.1 - 0.00087 18.4 2.7 0.0011 18.0 0.7 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.13 EIW71676.1 - 0.058 12.5 0.0 0.15 11.2 0.1 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 EIW71676.1 - 0.087 12.5 2.5 2.3 8.0 0.3 2.5 2 0 0 2 2 2 0 Part of AAA domain PhoH PF02562.11 EIW71676.1 - 0.14 11.3 0.1 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Pkinase PF00069.20 EIW71677.1 - 7e-59 199.0 0.0 8.6e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71677.1 - 2.7e-37 128.2 0.0 3.9e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW71677.1 - 7.2e-08 31.7 0.0 1.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW71677.1 - 0.0055 16.4 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW71677.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIW71677.1 - 0.18 10.5 0.0 0.34 9.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ribonucleas_3_3 PF14622.1 EIW71678.1 - 1.4e-12 47.7 0.0 1.3e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like UCR_TM PF02921.9 EIW71679.1 - 1.7e-18 66.5 0.2 1.7e-18 66.5 0.2 1.6 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EIW71679.1 - 1.1e-16 60.1 0.0 1.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MBOAT_2 PF13813.1 EIW71680.1 - 4.6e-09 36.2 5.0 0.0022 18.0 2.4 2.9 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family Mod_r PF07200.8 EIW71681.1 - 9e-19 67.8 2.8 9e-15 54.8 0.7 2.1 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein BNIP3 PF06553.7 EIW71681.1 - 0.0032 16.8 0.1 0.0046 16.3 0.1 1.1 1 0 0 1 1 1 1 BNIP3 bZIP_1 PF00170.16 EIW71681.1 - 0.017 15.1 1.9 0.024 14.6 0.1 2.0 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EIW71681.1 - 0.023 14.5 2.1 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 EIW71681.1 - 0.096 13.0 0.9 0.19 12.0 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Herpes_UL6 PF01763.11 EIW71681.1 - 0.11 10.6 0.8 0.14 10.3 0.3 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like DUF3545 PF12065.3 EIW71681.1 - 0.13 11.9 1.0 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) DUF904 PF06005.7 EIW71681.1 - 0.32 11.3 2.9 0.93 9.8 2.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF3336 PF11815.3 EIW71682.1 - 2.4e-37 127.6 1.8 3.8e-37 127.0 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EIW71682.1 - 3.7e-22 79.2 0.1 9.3e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Trs65 PF12735.2 EIW71683.1 - 3.2e-28 98.9 2.7 3.2e-28 98.9 1.9 2.4 2 1 0 2 2 2 1 TRAPP trafficking subunit Trs65 DUF605 PF04652.11 EIW71683.1 - 6.1 6.1 16.3 2 7.7 0.9 2.2 2 0 0 2 2 2 0 Vta1 like tRNA-synt_2 PF00152.15 EIW71684.1 - 1.7e-67 227.5 0.0 2.3e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIW71684.1 - 7.4e-12 44.9 0.7 1.4e-11 44.0 0.5 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1682 PF07946.9 EIW71684.1 - 0.011 14.6 0.2 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) tRNA_anti-like PF12869.2 EIW71684.1 - 0.018 14.5 0.4 0.031 13.7 0.3 1.4 1 0 0 1 1 1 0 tRNA_anti-like Rep_fac-A_3 PF08661.6 EIW71684.1 - 0.047 13.5 0.1 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Replication factor A protein 3 TPP1 PF10341.4 EIW71684.1 - 0.09 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD WW PF00397.21 EIW71685.1 - 0.034 14.0 0.1 0.034 14.0 0.1 3.0 3 0 0 3 3 3 0 WW domain Mito_fiss_reg PF05308.6 EIW71685.1 - 1.3 8.2 8.1 2 7.6 5.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator EamA PF00892.15 EIW71686.1 - 3.5e-07 30.2 39.7 0.00021 21.3 12.2 3.4 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EIW71686.1 - 3.9e-06 27.0 13.4 3.9e-06 27.0 9.3 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EIW71686.1 - 3e-05 23.7 0.8 3e-05 23.7 0.5 2.8 3 1 0 3 3 3 1 Triose-phosphate Transporter family Cgr1 PF03879.9 EIW71688.1 - 6.1e-20 71.4 24.5 7.7e-20 71.0 17.0 1.0 1 0 0 1 1 1 1 Cgr1 family CAF-1_p150 PF11600.3 EIW71688.1 - 0.15 11.4 21.5 0.17 11.2 14.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDHD PF02862.12 EIW71688.1 - 0.16 11.7 7.6 0.17 11.6 5.3 1.0 1 0 0 1 1 1 0 DDHD domain DOR PF14839.1 EIW71688.1 - 0.3 10.8 6.2 0.34 10.6 4.3 1.3 1 0 0 1 1 1 0 DOR family HXXSHH PF07586.6 EIW71688.1 - 1.4 7.8 4.7 1.6 7.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Atrophin-1 PF03154.10 EIW71688.1 - 2.4 6.1 13.2 2.6 6.0 9.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family Tom37_C PF11801.3 EIW71688.1 - 2.5 7.9 6.1 3.2 7.5 4.2 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain APG6 PF04111.7 EIW71688.1 - 2.6 7.0 7.9 3 6.7 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2058 PF09831.4 EIW71688.1 - 5.1 6.9 12.4 6.7 6.5 8.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Atg14 PF10186.4 EIW71688.1 - 6.6 5.5 10.9 7.9 5.3 7.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_S49_N PF08496.5 EIW71688.1 - 6.9 6.4 8.5 9.2 6.0 5.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Tim54 PF11711.3 EIW71689.1 - 0.09 11.3 0.6 0.64 8.5 0.1 2.5 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 PLDc_2 PF13091.1 EIW71690.1 - 3.5e-15 55.8 0.1 2.6e-08 33.6 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EIW71690.1 - 6.9e-12 44.7 1.8 2.1e-06 27.3 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif CDC45 PF02724.9 EIW71691.1 - 6.9e-195 648.6 0.0 8.3e-195 648.4 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Glyco_hydro_18 PF00704.23 EIW71692.1 - 4.4e-11 42.8 5.1 4.4e-11 42.8 3.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DUF605 PF04652.11 EIW71692.1 - 2.8 7.2 9.0 4.1 6.7 6.2 1.2 1 0 0 1 1 1 0 Vta1 like RSN1_TM PF13967.1 EIW71693.1 - 0.00053 19.5 0.2 0.00053 19.5 0.1 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIW71693.1 - 0.0032 17.9 0.0 0.0071 16.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Sgf11 PF08209.6 EIW71694.1 - 2.9e-10 39.2 0.3 2.9e-10 39.2 0.2 1.6 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) S1 PF00575.18 EIW71695.1 - 5.3e-59 196.2 17.5 1.2e-12 47.6 0.4 9.7 10 0 0 10 10 10 7 S1 RNA binding domain Suf PF05843.9 EIW71695.1 - 2.1e-09 37.5 11.6 2.1e-08 34.2 0.1 3.4 2 1 2 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EIW71695.1 - 5.8e-06 26.5 0.9 3.3 8.1 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW71695.1 - 9e-05 23.0 1.0 0.0033 18.0 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat EXOSC1 PF10447.4 EIW71695.1 - 9.2e-05 22.3 1.7 0.044 13.7 0.1 4.1 4 0 0 4 4 4 1 Exosome component EXOSC1/CSL4 TPR_14 PF13428.1 EIW71695.1 - 0.00015 22.1 0.3 20 6.1 0.0 5.3 4 2 1 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EIW71695.1 - 0.0098 14.8 3.7 1.5 7.6 0.1 2.8 2 1 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_6 PF13174.1 EIW71695.1 - 0.021 15.2 0.3 0.39 11.2 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.4 EIW71695.1 - 0.094 12.0 1.4 4.1 6.7 0.2 2.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_12 PF13424.1 EIW71695.1 - 0.31 10.9 2.1 3.6 7.5 0.0 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat Actin PF00022.14 EIW71696.1 - 2.3e-33 115.1 0.0 4e-32 111.1 0.0 2.6 1 1 0 1 1 1 1 Actin CBM_21 PF03370.8 EIW71697.1 - 1.5e-27 95.8 0.0 2.4e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit TB2_DP1_HVA22 PF03134.14 EIW71698.1 - 3.9e-21 74.6 0.8 7.7e-21 73.6 0.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family HMA PF00403.21 EIW71699.1 - 0.00027 21.0 0.3 0.00053 20.0 0.2 1.5 1 1 0 1 1 1 1 Heavy-metal-associated domain DUF460 PF04312.8 EIW71699.1 - 0.074 12.5 0.0 0.091 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Evr1_Alr PF04777.8 EIW71700.1 - 1e-28 99.0 0.0 1.3e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family zf-CSL PF05207.8 EIW71700.1 - 0.28 10.7 2.5 8.3 6.0 0.0 2.2 2 0 0 2 2 2 0 CSL zinc finger DDE_1 PF03184.14 EIW71701.1 - 3.6e-31 108.0 0.0 5.7e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW71701.1 - 2.3e-10 40.3 0.0 6.8e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW71701.1 - 0.00047 19.9 0.0 0.0016 18.1 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EIW71701.1 - 0.003 17.0 0.0 0.0079 15.7 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain MSA_2 PF00985.12 EIW71705.1 - 1.4 8.9 6.2 1.5 8.9 4.3 1.0 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family DUF4661 PF15576.1 EIW71705.1 - 2.4 7.7 6.0 2.6 7.6 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) rve PF00665.21 EIW71706.1 - 7.9e-22 77.6 0.0 1.8e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EIW71706.1 - 1.1e-18 67.4 0.0 2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EIW71706.1 - 5.8e-09 35.4 0.5 1.2e-08 34.4 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EIW71706.1 - 2.3e-06 27.5 0.2 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EIW71706.1 - 2.8e-06 27.0 0.0 6.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIW71706.1 - 2.8e-06 27.7 0.0 7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIW71706.1 - 0.0039 17.1 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EIW71706.1 - 0.0041 16.9 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.1 EIW71706.1 - 0.044 13.3 0.3 0.2 11.2 0.2 2.2 1 0 0 1 1 1 0 Integrase core domain zf-H2C2 PF09337.5 EIW71706.1 - 0.19 11.1 0.0 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger Asp_protease PF09668.5 EIW71706.1 - 0.28 10.7 0.0 0.57 9.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF2587 PF10759.4 EIW71707.1 - 0.042 13.2 0.1 0.12 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) TatD_DNase PF01026.16 EIW71710.1 - 4.2e-50 170.3 0.0 5.1e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase PTE PF02126.13 EIW71710.1 - 0.013 14.4 0.0 0.031 13.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotriesterase family Amidohydro_2 PF04909.9 EIW71710.1 - 0.034 13.6 0.0 0.92 9.0 0.0 2.9 2 1 0 2 2 2 0 Amidohydrolase TPR_14 PF13428.1 EIW71711.1 - 3.3e-09 36.5 7.5 2.7 8.8 0.0 9.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIW71711.1 - 5.3e-07 29.1 8.3 0.26 10.9 0.0 6.7 6 2 2 8 8 8 1 TPR repeat TPR_16 PF13432.1 EIW71711.1 - 6.5e-06 26.6 11.0 0.56 10.9 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW71711.1 - 3.6e-05 23.6 7.7 1.5 8.7 0.0 6.3 6 2 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW71711.1 - 0.00013 21.5 1.3 38 4.4 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.1 EIW71711.1 - 0.00029 19.9 3.8 0.00094 18.3 0.1 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW71711.1 - 0.0059 16.1 2.3 38 4.1 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EIW71711.1 - 0.0064 16.2 9.3 0.36 10.6 1.5 5.3 5 1 0 5 5 5 1 Mad3/BUB1 homology region 1 TPR_2 PF07719.12 EIW71711.1 - 0.0085 15.9 17.9 0.074 13.0 0.0 7.1 9 0 0 9 9 9 2 Tetratricopeptide repeat Suf PF05843.9 EIW71711.1 - 0.02 14.6 10.3 0.043 13.5 0.2 4.5 4 1 0 5 5 5 0 Suppressor of forked protein (Suf) PPR_3 PF13812.1 EIW71711.1 - 0.096 13.0 0.2 1.7 9.1 0.0 3.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain HSP90 PF00183.13 EIW71712.1 - 7.6e-97 324.9 1.2 3.1e-95 319.5 0.8 2.4 1 1 0 1 1 1 1 Hsp90 protein WD40 PF00400.27 EIW71713.1 - 1.2e-08 34.5 2.0 0.0011 18.7 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Complex1_LYR PF05347.10 EIW71714.1 - 2.1e-09 37.0 2.8 3.4e-09 36.3 1.9 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIW71714.1 - 8e-07 29.1 2.0 1.2e-06 28.6 1.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Histone PF00125.19 EIW71716.1 - 3.1e-30 104.1 0.6 4.7e-30 103.5 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW71716.1 - 2.8e-05 24.2 0.1 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIW71716.1 - 0.0045 17.0 0.1 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIW71716.1 - 0.012 14.8 1.6 0.02 14.1 1.1 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EIW71716.1 - 0.08 12.6 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated S_tail_recep_bd PF14928.1 EIW71718.1 - 0.12 12.6 2.3 0.32 11.2 1.4 1.9 1 1 1 2 2 2 0 Short tail fibre protein receptor-binding domain NTR2 PF15458.1 EIW71719.1 - 1.8e-48 165.0 12.8 1.8e-48 165.0 8.9 2.4 3 0 0 3 3 3 1 Nineteen complex-related protein 2 GCFC PF07842.7 EIW71719.1 - 0.00048 19.5 0.0 0.034 13.5 0.0 2.7 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein ABC_tran PF00005.22 EIW71721.1 - 7.1e-50 168.8 0.1 1.1e-28 100.2 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW71721.1 - 8.4e-21 74.5 22.3 3.9e-11 42.8 4.1 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EIW71721.1 - 1.2e-08 34.4 7.9 0.0026 17.0 2.9 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW71721.1 - 1.3e-06 27.9 0.2 0.00043 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW71721.1 - 0.00011 21.6 2.9 0.25 10.9 0.2 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EIW71721.1 - 0.00014 21.4 0.1 0.38 10.2 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 EIW71721.1 - 0.00015 21.9 2.9 4 7.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EIW71721.1 - 0.00017 21.6 0.8 0.51 10.3 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EIW71721.1 - 0.00032 20.7 3.7 0.44 10.4 0.5 4.1 2 2 1 3 3 3 1 AAA domain AAA_23 PF13476.1 EIW71721.1 - 0.00051 20.4 0.9 0.7 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EIW71721.1 - 0.00092 18.1 0.2 0.37 9.6 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein SbcCD_C PF13558.1 EIW71721.1 - 0.03 14.2 0.2 2 8.4 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EIW71721.1 - 0.053 12.9 2.7 7.6 5.8 0.2 2.9 3 0 0 3 3 3 0 AAA-like domain KaiC PF06745.8 EIW71721.1 - 0.062 12.4 0.5 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 EIW71721.1 - 0.065 12.8 3.3 3.3 7.3 0.3 2.9 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 EIW71721.1 - 0.076 12.2 0.3 5.7 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EIW71721.1 - 0.078 13.8 0.3 0.44 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EIW71721.1 - 0.081 12.3 0.0 0.081 12.3 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EIW71721.1 - 0.18 12.1 2.3 2.7 8.3 0.3 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EIW71721.1 - 0.19 11.9 4.0 14 5.8 0.1 3.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EIW71721.1 - 0.83 8.4 6.6 5.4 5.7 0.3 3.3 4 0 0 4 4 4 0 NB-ARC domain AAA_19 PF13245.1 EIW71721.1 - 1.1 9.0 3.9 7.3 6.4 0.1 3.7 4 0 0 4 4 4 0 Part of AAA domain DUF1604 PF07713.8 EIW71722.1 - 8.8e-36 121.5 3.0 8.8e-36 121.5 2.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EIW71722.1 - 7.9e-06 25.5 0.3 7.9e-06 25.5 0.2 2.6 3 0 0 3 3 3 1 G-patch domain Sod_Fe_C PF02777.13 EIW71723.1 - 2.1e-06 27.5 0.5 0.0012 18.6 0.2 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Abhydrolase_2 PF02230.11 EIW71723.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PNRC PF15365.1 EIW71725.1 - 0.032 14.2 4.2 0.1 12.6 0.4 3.7 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator Gar1 PF04410.9 EIW71726.1 - 1.3e-32 112.4 0.0 1.3e-32 112.4 0.0 2.9 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region PTPlike_phytase PF14566.1 EIW71727.1 - 1.7e-115 381.8 0.0 1.5e-39 135.4 0.1 3.5 3 0 0 3 3 3 3 Inositol hexakisphosphate L27 PF02828.11 EIW71729.1 - 0.1 12.3 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 L27 domain Prominin PF05478.6 EIW71729.1 - 0.28 8.6 2.4 0.44 8.0 1.7 1.3 1 0 0 1 1 1 0 Prominin DUF948 PF06103.6 EIW71729.1 - 0.39 10.6 4.5 3.1 7.7 0.0 3.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TPD52 PF04201.10 EIW71729.1 - 2.8 7.6 15.1 0.031 14.0 3.6 2.6 1 1 1 3 3 3 0 Tumour protein D52 family Metallophos PF00149.23 EIW71731.1 - 1.9e-06 27.4 3.8 9.7e-06 25.1 2.6 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Brix PF04427.13 EIW71732.1 - 5.7e-48 163.1 0.7 7.9e-48 162.6 0.5 1.2 1 0 0 1 1 1 1 Brix domain PUF PF00806.14 EIW71733.1 - 0.00096 18.5 0.0 0.068 12.6 0.0 3.5 3 0 0 3 3 3 1 Pumilio-family RNA binding repeat SlyX PF04102.7 EIW71733.1 - 0.0038 17.5 2.0 0.019 15.3 0.0 2.7 2 0 0 2 2 2 1 SlyX Excalibur PF05901.6 EIW71734.1 - 0.028 14.7 0.1 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Excalibur calcium-binding domain DUF4167 PF13763.1 EIW71734.1 - 0.038 14.0 0.1 0.046 13.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4167) NDUFB10 PF10249.4 EIW71734.1 - 0.081 13.0 0.2 0.087 12.9 0.2 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 FdsD PF11390.3 EIW71734.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Memo PF01875.12 EIW71735.1 - 1.6e-60 204.2 0.0 2.1e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein PGM_PMM_I PF02878.11 EIW71736.1 - 6.5e-17 61.3 0.0 1.7e-08 34.0 0.0 2.6 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EIW71736.1 - 2.2e-12 47.1 0.0 6.4e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EIW71736.1 - 4.2e-10 39.5 0.0 1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EIW71736.1 - 0.00036 20.5 0.2 0.0012 18.8 0.2 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III MA3 PF02847.12 EIW71737.1 - 1.2e-26 92.6 0.0 2.7e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 EIW71737.1 - 1.8e-26 92.8 2.3 3.7e-26 91.8 0.1 2.3 2 1 0 2 2 2 1 MIF4G domain SSP160 PF06933.6 EIW71737.1 - 0.78 7.6 4.0 1.2 7.0 2.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 S-antigen PF05756.6 EIW71737.1 - 2.2 8.3 8.2 7.4 6.6 5.7 1.8 1 0 0 1 1 1 0 S-antigen protein HALZ PF02183.13 EIW71738.1 - 0.0023 17.5 1.2 0.0058 16.3 0.8 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper AAA_13 PF13166.1 EIW71738.1 - 0.029 12.8 3.8 0.04 12.3 2.7 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.3 EIW71738.1 - 0.039 13.2 2.3 0.048 12.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATP-synt_D PF01813.12 EIW71738.1 - 0.047 13.2 1.8 0.14 11.6 0.9 1.8 2 0 0 2 2 2 0 ATP synthase subunit D APG6 PF04111.7 EIW71738.1 - 0.078 12.0 4.9 0.11 11.5 3.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 EIW71738.1 - 0.16 11.7 9.3 0.24 11.1 6.5 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EIW71738.1 - 0.17 9.7 1.0 0.16 9.7 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EIW71738.1 - 0.27 10.7 4.0 0.27 10.7 1.7 1.8 1 1 1 2 2 2 0 Septum formation initiator PA26 PF04636.8 EIW71738.1 - 0.31 9.6 3.4 0.39 9.3 2.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) bZIP_2 PF07716.10 EIW71738.1 - 0.39 10.5 3.7 0.62 9.9 2.0 1.8 1 1 0 1 1 1 0 Basic region leucine zipper Seryl_tRNA_N PF02403.17 EIW71738.1 - 0.87 9.6 6.5 0.93 9.5 2.0 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain OPA3 PF07047.7 EIW71738.1 - 1.2 8.8 8.2 0.31 10.7 2.1 2.4 1 1 1 2 2 2 0 Optic atrophy 3 protein (OPA3) Transposase_22 PF02994.9 EIW71738.1 - 1.6 7.1 7.1 2.1 6.7 4.6 1.5 1 1 1 2 2 2 0 L1 transposable element MMS19_N PF14500.1 EIW71740.1 - 3.9e-86 288.5 0.5 1.4e-85 286.7 0.1 2.2 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EIW71740.1 - 7.7e-67 225.8 1.7 1.2e-66 225.1 0.0 2.1 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 EIW71740.1 - 1.7e-07 31.3 3.0 2.5 8.4 0.0 6.4 5 2 1 6 6 6 2 HEAT repeats HEAT PF02985.17 EIW71740.1 - 0.014 15.4 4.7 17 5.8 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 EIW71740.1 - 0.027 14.9 3.6 17 6.0 0.1 5.5 4 2 1 5 5 5 0 HEAT-like repeat Xpo1 PF08389.7 EIW71740.1 - 0.044 13.7 0.3 15 5.5 0.0 3.4 3 1 0 3 3 3 0 Exportin 1-like protein Adaptin_N PF01602.15 EIW71741.1 - 3e-72 243.6 0.0 4.7e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EIW71741.1 - 1.4e-05 24.7 1.1 0.09 12.8 0.1 4.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EIW71741.1 - 7.3e-05 22.9 2.6 0.38 11.0 0.0 3.5 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EIW71741.1 - 0.00039 20.3 0.0 0.83 9.4 0.0 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EIW71741.1 - 0.0024 17.7 0.2 0.056 13.3 0.1 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EIW71741.1 - 0.23 12.0 6.5 14 6.3 0.1 5.2 6 0 0 6 6 6 0 HEAT-like repeat RhoGAP PF00620.22 EIW71743.1 - 8.7e-13 48.1 0.1 4.3e-10 39.4 0.0 2.6 2 0 0 2 2 2 2 RhoGAP domain FCH PF00611.18 EIW71743.1 - 4.6e-07 29.9 0.3 1.1e-06 28.7 0.2 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EIW71743.1 - 1e-05 25.1 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Secretin_N_2 PF07655.8 EIW71744.1 - 0.0043 17.4 6.8 0.007 16.7 4.7 1.2 1 0 0 1 1 1 1 Secretin N-terminal domain Rad9 PF04139.8 EIW71745.1 - 3.5e-45 154.0 0.0 4.3e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Rad9 MRVI1 PF05781.7 EIW71745.1 - 0.22 9.8 4.6 0.33 9.2 3.2 1.2 1 0 0 1 1 1 0 MRVI1 protein MAP65_ASE1 PF03999.7 EIW71745.1 - 0.54 8.7 2.8 0.77 8.2 2.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SET PF00856.23 EIW71746.1 - 3.3e-08 34.0 0.2 2.2e-07 31.3 0.1 2.3 1 1 0 1 1 1 1 SET domain HEAT_EZ PF13513.1 EIW71747.1 - 1.7e-21 76.0 16.3 7.2e-09 35.8 0.0 10.5 9 3 4 13 13 13 4 HEAT-like repeat HEAT PF02985.17 EIW71747.1 - 2.3e-15 55.2 11.5 0.036 14.1 0.0 9.6 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 EIW71747.1 - 2.1e-14 53.5 1.4 0.00066 19.9 0.1 5.7 3 2 2 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EIW71747.1 - 2.3e-10 40.7 0.0 0.0061 16.9 0.0 5.3 4 1 1 5 5 5 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EIW71747.1 - 2.4e-05 24.2 0.1 0.18 11.6 0.1 3.6 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EIW71747.1 - 0.00021 19.7 0.0 0.04 12.2 0.0 2.7 1 1 1 2 2 2 2 Adaptin N terminal region Arm PF00514.18 EIW71747.1 - 0.0033 17.2 7.1 5.7 6.9 0.1 5.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 EIW71747.1 - 0.028 13.1 0.4 2 7.0 0.0 3.1 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Proteasom_PSMB PF10508.4 EIW71747.1 - 0.18 10.0 0.0 6.9 4.8 0.0 2.3 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit TFIIA PF03153.8 EIW71747.1 - 2.4 7.9 5.3 3.4 7.4 3.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SMC_N PF02463.14 EIW71748.1 - 5.2e-77 258.0 0.7 1.2e-76 256.7 0.5 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIW71748.1 - 7.8e-26 90.4 0.0 2.6e-25 88.7 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EIW71748.1 - 4e-10 40.1 21.3 5.3e-06 26.6 0.1 4.0 3 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EIW71748.1 - 1.1e-06 28.0 0.0 2.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mnd1 PF03962.10 EIW71748.1 - 4.2e-05 23.2 0.3 4.2e-05 23.2 0.2 8.6 3 2 4 8 8 8 2 Mnd1 family TPR_MLP1_2 PF07926.7 EIW71748.1 - 0.0015 18.2 10.7 0.0015 18.2 7.4 7.3 3 2 0 6 6 6 2 TPR/MLP1/MLP2-like protein ABC_tran PF00005.22 EIW71748.1 - 0.27 11.5 0.0 0.27 11.5 0.0 6.2 3 2 1 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 EIW71748.1 - 3.2 6.8 39.3 0.075 12.1 2.2 4.9 3 2 1 5 5 5 0 Reovirus sigma C capsid protein SlyX PF04102.7 EIW71748.1 - 5.6 7.4 40.1 0.034 14.5 0.8 7.8 5 3 2 7 7 7 0 SlyX Coprogen_oxidas PF01218.13 EIW71749.1 - 6e-123 409.1 0.0 8e-123 408.7 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase ABC1 PF03109.11 EIW71750.1 - 1.6e-30 105.5 0.0 2.5e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 ABC1 family eIF-3c_N PF05470.7 EIW71751.1 - 7.4e-138 460.2 10.8 7.4e-138 460.2 7.5 3.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EIW71751.1 - 1.2e-12 48.0 0.7 3.9e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 PCI domain Daxx PF03344.10 EIW71751.1 - 0.005 15.3 15.4 0.008 14.7 10.7 1.2 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 EIW71751.1 - 0.02 12.9 9.4 0.036 12.1 6.5 1.5 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 EIW71751.1 - 1 9.2 6.2 0.96 9.2 2.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TPR_6 PF13174.1 EIW71751.1 - 8.8 7.0 7.2 42 4.8 0.1 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Cwf_Cwc_15 PF04889.7 EIW71751.1 - 9 5.9 27.9 1.9 8.1 16.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Lgl_C PF08596.5 EIW71752.1 - 2.5e-82 276.4 0.0 3.3e-82 276.0 0.0 1.1 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal Dpy-30 PF05186.8 EIW71753.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Dpy-30 motif BRF1 PF07741.8 EIW71754.1 - 0.0039 17.3 4.2 0.44 10.7 0.2 2.8 2 0 0 2 2 2 2 Brf1-like TBP-binding domain zf-CCHC PF00098.18 EIW71754.1 - 0.031 14.2 4.3 0.064 13.2 3.0 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIW71754.1 - 0.055 12.9 0.2 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Resolvase PF00239.16 EIW71754.1 - 0.12 12.2 10.6 0.027 14.3 2.1 2.6 2 0 0 2 2 2 0 Resolvase, N terminal domain MSP1_C PF07462.6 EIW71755.1 - 7.7 4.7 5.8 14 3.8 4.0 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus WD40 PF00400.27 EIW71757.1 - 2.4e-24 84.2 3.7 8.9e-07 28.5 0.0 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat Nup160 PF11715.3 EIW71757.1 - 0.026 12.6 1.4 2.1 6.3 1.0 2.1 1 1 0 1 1 1 0 Nucleoporin Nup120/160 DUF1611 PF07755.6 EIW71757.1 - 0.051 12.2 0.0 0.084 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1611) NAD_binding_10 PF13460.1 EIW71758.1 - 2.5e-11 43.9 0.0 3.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 EIW71758.1 - 2.4e-06 26.2 0.0 3.6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 HIM1 DUF1471 PF07338.8 EIW71758.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Semialdhyde_dh PF01118.19 EIW71758.1 - 0.087 13.1 0.0 0.28 11.5 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain EMP70 PF02990.11 EIW71759.1 - 1.9e-184 613.9 0.8 1.9e-184 613.9 0.5 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 GSHPx PF00255.14 EIW71760.1 - 1.6e-38 130.4 0.1 2e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EIW71760.1 - 1.8e-06 27.6 0.1 3.1e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW71760.1 - 9.3e-06 25.2 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin CoaE PF01121.15 EIW71761.1 - 1.2e-55 187.7 0.0 1.6e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EIW71761.1 - 2.8e-05 24.9 0.0 5.5e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW71761.1 - 0.0031 17.8 0.0 0.0071 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Erf4 PF10256.4 EIW71762.1 - 1.7e-26 92.4 0.1 2.1e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Abhydrolase_6 PF12697.2 EIW71763.1 - 2e-30 106.3 3.4 2e-30 106.3 2.3 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW71763.1 - 1.7e-20 73.5 0.0 5.3e-20 71.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW71763.1 - 7e-17 61.5 0.3 1.6e-14 53.8 0.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EIW71763.1 - 2.3e-06 27.3 0.0 0.00051 19.6 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 EIW71763.1 - 0.00015 20.3 0.0 0.00049 18.6 0.0 1.8 2 0 0 2 2 2 1 Ndr family BAAT_C PF08840.6 EIW71763.1 - 0.00022 21.0 0.0 0.091 12.4 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EIW71763.1 - 0.00026 20.2 0.0 0.25 10.5 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 EIW71763.1 - 0.00037 20.1 0.0 0.00081 19.0 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Esterase PF00756.15 EIW71763.1 - 0.00071 19.0 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EIW71763.1 - 0.0053 16.2 0.0 0.61 9.4 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EIW71763.1 - 0.0076 15.8 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EIW71763.1 - 0.008 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein UPF0227 PF05728.7 EIW71763.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DLH PF01738.13 EIW71763.1 - 0.011 15.0 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2305 PF10230.4 EIW71763.1 - 0.025 14.0 0.0 0.071 12.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 EIW71763.1 - 0.088 13.0 0.0 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain DHBP_synthase PF00926.14 EIW71764.1 - 3.5e-71 238.4 0.0 4e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase zf-CCHC PF00098.18 EIW71767.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW71767.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW71767.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Chromo PF00385.19 EIW71768.1 - 2.9e-10 39.6 0.5 4e-10 39.2 0.3 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EIW71768.1 - 0.038 13.8 0.3 0.076 12.9 0.2 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DDE_3 PF13358.1 EIW71769.1 - 6.7e-11 42.1 0.5 9.1e-11 41.6 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_2 PF07727.9 EIW71771.1 - 9.7e-71 237.5 0.0 1.4e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIW71771.1 - 1.2e-19 70.5 0.0 2.5e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 EIW71771.1 - 0.0015 18.3 0.0 0.0055 16.4 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease rve_3 PF13683.1 EIW71771.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 EIW71771.1 - 0.09 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glypican PF01153.14 EIW71772.1 - 0.17 10.4 1.7 0.26 9.8 1.2 1.3 1 0 0 1 1 1 0 Glypican Upf2 PF04050.9 EIW71773.1 - 0.67 9.6 5.0 0.96 9.1 3.4 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Nop14 PF04147.7 EIW71773.1 - 3.8 5.2 6.0 5 4.9 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EIW71773.1 - 4.5 6.4 8.2 6.4 5.9 5.7 1.1 1 0 0 1 1 1 0 SDA1 DUF35_N PF12172.3 EIW71774.1 - 0.02 14.7 0.5 0.046 13.6 0.4 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Gemini_C4 PF01492.12 EIW71774.1 - 0.11 12.2 0.1 0.59 9.9 0.0 2.0 2 0 0 2 2 2 0 Geminivirus C4 protein FAD_binding_2 PF00890.19 EIW71776.1 - 2.7e-125 418.5 2.7 3.3e-125 418.2 1.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EIW71776.1 - 1.9e-47 160.3 0.4 2.7e-47 159.8 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EIW71776.1 - 2e-07 31.1 0.0 3e-05 24.0 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW71776.1 - 7.7e-07 28.4 0.7 0.0016 17.6 0.1 2.6 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EIW71776.1 - 1.5e-05 24.1 1.3 0.029 13.2 2.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EIW71776.1 - 0.0011 17.9 0.1 0.0067 15.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW71776.1 - 0.022 13.8 0.4 0.039 13.0 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain DUF600 PF04634.7 EIW71776.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF600 HI0933_like PF03486.9 EIW71776.1 - 0.27 9.6 3.0 0.51 8.7 0.8 2.3 3 0 0 3 3 3 0 HI0933-like protein Topoisom_I_N PF02919.10 EIW71777.1 - 7.7e-95 316.2 1.0 7.7e-95 316.2 0.7 3.8 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EIW71777.1 - 4.4e-84 281.2 1.6 1.2e-83 279.8 1.1 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EIW71777.1 - 3.5e-29 100.2 0.3 3.5e-29 100.2 0.2 2.2 2 0 0 2 2 2 1 C-terminal topoisomerase domain Arf PF00025.16 EIW71778.1 - 1.2e-54 184.1 0.0 1.4e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIW71778.1 - 3.5e-10 39.5 0.0 4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EIW71778.1 - 2.7e-09 36.2 0.2 3.8e-06 25.8 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EIW71778.1 - 1.7e-08 33.9 0.0 2.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EIW71778.1 - 2.9e-06 27.7 0.0 3.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EIW71778.1 - 8.6e-06 25.3 0.0 0.0003 20.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW71778.1 - 1.3e-05 25.1 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EIW71778.1 - 1.3e-05 24.4 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ArgK PF03308.11 EIW71778.1 - 0.063 12.0 0.0 0.72 8.5 0.0 2.1 2 0 0 2 2 2 0 ArgK protein FeoB_N PF02421.13 EIW71778.1 - 0.16 11.2 0.4 0.41 9.9 0.3 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B TOM13 PF08219.6 EIW71779.1 - 8e-13 47.9 0.7 1.8e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Outer membrane protein TOM13 APG6 PF04111.7 EIW71779.1 - 0.2 10.6 8.2 0.32 9.9 5.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 EIW71779.1 - 1.1 7.5 6.9 1.5 7.2 4.8 1.1 1 0 0 1 1 1 0 AAA domain HAUS6_N PF14661.1 EIW71779.1 - 1.7 7.9 6.9 2.3 7.4 4.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Rotamase PF00639.16 EIW71779.1 - 3 8.6 6.3 14 6.4 4.3 2.2 1 1 0 1 1 1 0 PPIC-type PPIASE domain DUF1675 PF07897.6 EIW71779.1 - 3.6 7.3 10.0 5.2 6.8 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4407 PF14362.1 EIW71779.1 - 6.6 5.6 8.9 10 5.0 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_C78 PF07910.8 EIW71780.1 - 1.7e-36 125.3 0.0 3.2e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 Bromodomain PF00439.20 EIW71781.1 - 5e-25 87.2 0.0 9.6e-25 86.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Myb_DNA-binding PF00249.26 EIW71781.1 - 0.00092 19.2 0.1 0.0023 17.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain PCI PF01399.22 EIW71782.1 - 1.7e-09 37.8 0.1 3.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 PCI domain LPAM_1 PF08139.7 EIW71783.1 - 0.049 13.8 0.1 0.079 13.2 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site FixP_N PF14715.1 EIW71783.1 - 0.07 12.5 0.2 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP HTH_Tnp_Tc3_2 PF01498.13 EIW71785.1 - 1.2e-07 31.7 0.2 1.6e-07 31.2 0.2 1.2 1 0 0 1 1 1 1 Transposase RAP PF08373.5 EIW71786.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 RAP domain CwfJ_C_2 PF04676.9 EIW71786.1 - 0.069 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 RVT_1 PF00078.22 EIW71788.1 - 7e-09 35.3 0.0 1.4e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EIW71788.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.14 EIW71789.1 - 1.5e-44 151.7 0.0 1.7e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA PF00004.24 EIW71793.1 - 4.9e-55 185.3 0.0 5.2e-45 152.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW71793.1 - 4e-09 36.7 1.4 0.0018 18.2 0.1 3.7 2 1 1 3 3 3 2 AAA ATPase domain UPF0079 PF02367.12 EIW71793.1 - 2.8e-07 30.1 0.5 0.016 14.8 0.0 2.9 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EIW71793.1 - 8.7e-07 29.7 0.0 0.0009 20.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EIW71793.1 - 1.3e-06 28.5 0.1 0.0019 18.3 0.0 3.5 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIW71793.1 - 1.8e-05 24.4 0.0 0.0068 16.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EIW71793.1 - 7.8e-05 22.3 0.0 0.004 16.8 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EIW71793.1 - 8.3e-05 22.4 0.0 0.081 12.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIW71793.1 - 9.6e-05 21.5 0.0 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EIW71793.1 - 0.0001 21.3 0.0 0.41 9.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) TIP49 PF06068.8 EIW71793.1 - 0.00012 20.9 0.0 0.0049 15.6 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 EIW71793.1 - 0.00024 20.5 0.0 0.0027 17.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EIW71793.1 - 0.00045 19.6 0.0 0.0033 16.8 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 EIW71793.1 - 0.00058 20.1 0.0 0.064 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EIW71793.1 - 0.0012 18.0 0.0 0.0079 15.3 0.0 2.0 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.17 EIW71793.1 - 0.0026 17.9 0.0 0.024 14.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Sigma54_activat PF00158.21 EIW71793.1 - 0.0027 17.1 0.0 1.5 8.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_2 PF07724.9 EIW71793.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 EIW71793.1 - 0.0039 16.8 0.2 0.039 13.5 0.2 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIW71793.1 - 0.0065 15.6 0.1 0.02 14.0 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EIW71793.1 - 0.0074 15.4 0.0 0.17 10.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.1 EIW71793.1 - 0.011 15.2 0.3 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.12 EIW71793.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 EIW71793.1 - 0.014 15.0 0.1 1.4 8.5 0.0 2.8 3 0 0 3 3 2 0 NACHT domain AAA_28 PF13521.1 EIW71793.1 - 0.019 14.9 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EIW71793.1 - 0.021 14.9 0.0 2.8 8.0 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 EIW71793.1 - 0.024 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 EIW71793.1 - 0.025 14.5 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EIW71793.1 - 0.027 14.0 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EIW71793.1 - 0.17 12.1 0.0 8.7 6.6 0.0 2.5 2 0 0 2 2 2 0 ABC transporter PPV_E1_C PF00519.12 EIW71793.1 - 0.44 9.1 0.0 0.8 8.2 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase FAT PF02259.18 EIW71794.1 - 8.4e-41 140.1 0.2 2.1e-40 138.7 0.1 1.7 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EIW71794.1 - 1.5e-40 139.1 0.0 3.8e-40 137.8 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EIW71794.1 - 9.7e-17 60.9 0.0 2.7e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 Rapamycin binding domain FATC PF02260.15 EIW71794.1 - 1.7e-12 46.5 0.1 5.4e-12 44.9 0.1 1.9 1 0 0 1 1 1 1 FATC domain APH PF01636.18 EIW71796.1 - 0.00076 19.2 0.1 0.00076 19.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Rot1 PF10681.4 EIW71798.1 - 4.6e-66 222.1 0.1 5.5e-66 221.9 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Lipocalin_4 PF13648.1 EIW71798.1 - 0.014 16.0 1.4 0.021 15.4 0.8 1.4 1 1 0 1 1 1 0 Lipocalin-like domain IF-2B PF01008.12 EIW71799.1 - 4e-59 199.9 0.0 4.8e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Myco_arth_vir_N PF09610.5 EIW71799.1 - 0.0061 16.4 0.3 0.0061 16.4 0.2 2.0 2 0 0 2 2 2 1 Mycoplasma virulence signal region (Myco_arth_vir_N) Fcf1 PF04900.7 EIW71799.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Fcf1 WD40 PF00400.27 EIW71800.1 - 0.079 12.8 7.2 9.4 6.3 0.1 5.1 6 0 0 6 6 6 0 WD domain, G-beta repeat RCC1 PF00415.13 EIW71801.1 - 2.9e-19 68.9 4.6 0.00022 21.3 0.0 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIW71801.1 - 5.1e-08 32.3 0.3 5.1e-08 32.3 0.2 5.3 8 0 0 8 8 8 1 Regulator of chromosome condensation (RCC1) repeat DUF1295 PF06966.7 EIW71803.1 - 5.8e-19 68.3 1.0 1.3e-09 37.7 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1295) Pox_A9 PF04835.7 EIW71803.1 - 0.098 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 A9 protein conserved region Arrestin_N PF00339.24 EIW71804.1 - 0.0015 18.3 0.1 0.0078 16.0 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EIW71804.1 - 0.005 16.3 0.2 0.03 13.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin_N terminal like Zn_clus PF00172.13 EIW71807.1 - 0.01 15.6 12.7 0.017 14.9 5.4 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGT PF00201.13 EIW71808.1 - 7.6e-14 51.1 0.1 1.1e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Aldo_ket_red PF00248.16 EIW71809.1 - 1.2e-26 93.2 0.0 4.5e-25 88.0 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Methyltransf_7 PF03492.10 EIW71809.1 - 0.018 13.8 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase Lectin_leg-like PF03388.8 EIW71811.1 - 1.5e-67 227.1 0.1 1.7e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EIW71811.1 - 0.00024 20.5 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain DUF1708 PF08101.6 EIW71811.1 - 0.077 11.8 0.1 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) zf-CCCH PF00642.19 EIW71812.1 - 1.2e-08 34.4 3.1 2.1e-08 33.6 2.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EIW71812.1 - 2.4e-07 30.6 10.6 3.9e-07 29.9 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW71812.1 - 3.3e-07 29.8 5.8 5.1e-07 29.2 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW71812.1 - 7.4e-06 25.5 8.5 1.2e-05 24.8 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EIW71812.1 - 1.2e-05 25.0 7.5 1.9e-05 24.3 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EIW71812.1 - 8.1e-05 22.4 8.4 0.00014 21.6 5.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EIW71812.1 - 9.6e-05 21.9 9.6 0.00016 21.2 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW71812.1 - 0.00049 19.7 4.4 0.0012 18.4 3.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EIW71812.1 - 0.0016 17.9 1.9 0.003 17.0 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Cytochrom_C552 PF02335.10 EIW71812.1 - 0.0079 14.9 1.0 0.01 14.5 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c552 zf-rbx1 PF12678.2 EIW71812.1 - 0.074 13.1 4.1 0.24 11.5 2.8 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 EIW71812.1 - 0.28 10.9 2.8 0.52 10.1 1.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4633 PF15464.1 EIW71812.1 - 0.41 10.4 3.4 0.88 9.4 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) zf-P11 PF03854.9 EIW71812.1 - 0.88 9.1 5.3 3.1 7.3 3.7 1.9 1 1 0 1 1 1 0 P-11 zinc finger Zn_clus PF00172.13 EIW71813.1 - 3.5e-07 29.9 10.5 3.5e-07 29.9 7.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tify PF06200.9 EIW71813.1 - 0.06 12.6 1.2 0.088 12.0 0.1 1.8 2 0 0 2 2 2 0 tify domain DUF1510 PF07423.6 EIW71814.1 - 0.0061 15.9 6.2 0.0061 15.9 4.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) DUF2681 PF10883.3 EIW71814.1 - 0.0084 16.2 2.6 0.0084 16.2 1.8 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2681) Plasmodium_Vir PF05795.6 EIW71814.1 - 0.31 10.1 4.2 0.61 9.2 2.9 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDC45 PF02724.9 EIW71814.1 - 0.46 8.4 19.4 0.0052 14.8 8.2 1.4 2 0 0 2 2 2 0 CDC45-like protein Peptidase_S49_N PF08496.5 EIW71814.1 - 7.3 6.3 11.1 0.33 10.7 2.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Thioredoxin PF00085.15 EIW71815.1 - 5.2e-06 26.0 0.0 8.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EIW71815.1 - 0.00017 20.3 0.0 0.0002 20.1 0.0 1.1 1 0 0 1 1 1 1 Phosducin UL97 PF06734.7 EIW71815.1 - 0.089 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 UL97 EIN3 PF04873.8 EIW71819.1 - 0.035 13.3 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Ethylene insensitive 3 OSCP PF00213.13 EIW71819.1 - 0.12 12.2 0.1 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit Mg_chelatase PF01078.16 EIW71821.1 - 0.04 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF1649 PF07855.7 EIW71825.1 - 1.3e-21 76.9 0.0 2.1e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Arrestin_C PF02752.17 EIW71825.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain CNH PF00780.17 EIW71826.1 - 1.3e-81 274.0 0.1 2.7e-81 273.0 0.0 1.5 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EIW71826.1 - 5.3e-46 155.9 0.0 9.6e-46 155.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EIW71826.1 - 2.1e-38 132.0 0.0 3.8e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EIW71826.1 - 5.7e-11 42.0 0.0 1.7e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 EIW71826.1 - 0.00075 19.6 0.2 0.098 12.8 0.0 3.3 3 1 0 3 3 3 1 PH domain Pkinase PF00069.20 EIW71827.1 - 2.3e-72 243.2 0.0 2.6e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71827.1 - 2.9e-34 118.3 0.0 3.5e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW71827.1 - 3.9e-05 22.7 0.0 0.00012 21.1 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIW71827.1 - 0.0044 16.0 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW71827.1 - 0.08 12.6 0.0 0.3 10.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family SPO22 PF08631.5 EIW71828.1 - 5.7e-13 48.5 0.3 5.7e-13 48.5 0.2 4.1 5 1 1 6 6 6 2 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 EIW71828.1 - 0.085 13.2 4.5 0.32 11.3 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIW71828.1 - 0.092 12.4 2.2 3 7.5 0.2 4.0 3 1 0 3 3 3 0 TPR repeat Kinocilin PF15033.1 EIW71828.1 - 0.18 11.3 0.3 0.45 10.0 0.2 1.6 1 0 0 1 1 1 0 Kinocilin protein TPR_12 PF13424.1 EIW71828.1 - 0.86 9.5 11.0 0.45 10.4 0.3 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 EIW71829.1 - 2.6e-32 109.4 13.6 9.9e-08 31.5 0.1 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EIW71829.1 - 8.5e-07 28.8 0.0 0.066 12.9 0.0 3.2 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EIW71829.1 - 0.0032 16.9 0.0 5.9 6.4 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.1 EIW71829.1 - 0.022 13.8 0.0 0.76 8.8 0.0 2.2 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 EIW71829.1 - 0.07 11.3 0.0 0.46 8.6 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) Mcm10 PF09332.6 EIW71829.1 - 0.4 9.9 1.2 0.62 9.3 0.8 1.2 1 0 0 1 1 1 0 Mcm10 replication factor WD40 PF00400.27 EIW71830.1 - 5.2e-20 70.5 10.1 1e-09 37.9 0.9 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40 PF00400.27 EIW71831.1 - 1.1e-11 44.1 2.2 0.00071 19.3 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1250 PF06855.7 EIW71831.1 - 0.13 11.8 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1250) DSHCT PF08148.7 EIW71834.1 - 6.4e-55 185.1 1.2 1.9e-54 183.6 0.3 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EIW71834.1 - 1.8e-20 73.1 0.0 3.6e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW71834.1 - 1.7e-05 24.6 0.0 4.7e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EIW71834.1 - 0.00069 18.8 0.0 0.0015 17.7 0.0 1.6 1 1 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.10 EIW71834.1 - 0.019 14.8 0.0 0.087 12.6 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RRM_1 PF00076.17 EIW71835.1 - 6.3e-08 32.1 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW71835.1 - 1.5e-05 24.7 0.0 2.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW71835.1 - 0.00013 21.8 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW71835.1 - 0.032 14.0 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 EIW71835.1 - 0.065 12.8 0.0 0.18 11.3 0.0 1.7 1 1 1 2 2 2 0 Calcipressin NIF PF03031.13 EIW71836.1 - 1.4e-22 80.0 0.0 2.2e-19 69.6 0.0 2.5 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EIW71836.1 - 2.2e-08 33.8 0.3 4.6e-08 32.8 0.2 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EIW71836.1 - 2.4e-07 30.7 0.0 7.8e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.1 EIW71836.1 - 0.015 14.9 0.0 0.043 13.4 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like UvrC_HhH_N PF08459.6 EIW71836.1 - 0.034 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal RGS-like PF09128.6 EIW71837.1 - 0.087 12.3 1.6 0.12 11.8 0.2 1.8 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain APG12 PF04110.8 EIW71838.1 - 2.4e-29 101.3 0.0 3.1e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Ufm1 PF03671.9 EIW71838.1 - 0.086 12.5 0.2 0.15 11.8 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin fold modifier 1 protein DUF2862 PF11061.3 EIW71838.1 - 0.13 11.9 0.2 12 5.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2862) DSPc PF00782.15 EIW71839.1 - 0.073 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Ribosomal_S2 PF00318.15 EIW71840.1 - 1.2e-43 148.8 0.1 6.6e-22 77.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 GST_N_3 PF13417.1 EIW71841.1 - 1.6e-08 34.6 0.0 3.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW71841.1 - 4.9e-08 33.0 0.0 9.6e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW71841.1 - 2.2e-06 27.5 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW71841.1 - 5.5e-05 23.0 0.0 0.00028 20.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW71841.1 - 0.085 12.7 0.1 0.4 10.5 0.1 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW71841.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_L11_N PF03946.9 EIW71842.1 - 4.8e-25 86.7 0.1 6.9e-25 86.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EIW71842.1 - 7.1e-21 74.1 0.0 9.7e-21 73.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Vezatin PF12632.2 EIW71844.1 - 4e-06 26.0 0.0 0.00085 18.4 0.0 3.3 2 1 0 2 2 2 1 Mysoin-binding motif of peroxisomes FixQ PF05545.6 EIW71844.1 - 0.68 9.6 0.2 1.3 8.7 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Ten1 PF12658.2 EIW71845.1 - 0.0014 18.3 0.0 0.006 16.3 0.0 1.9 1 1 0 1 1 1 1 Telomere capping, CST complex subunit DUF575 PF04746.7 EIW71845.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF575) Abhydrolase_6 PF12697.2 EIW71846.1 - 2.3e-22 79.9 0.0 3.2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW71846.1 - 3.2e-07 30.2 0.0 5.4e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW71846.1 - 3.2e-05 23.5 0.0 0.00016 21.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIW71846.1 - 4.3e-05 23.2 0.0 8.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EIW71846.1 - 0.0062 16.7 0.0 0.016 15.4 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 EIW71846.1 - 0.099 12.0 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thiolase_C PF02803.13 EIW71846.1 - 0.15 11.4 0.3 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Thiolase, C-terminal domain Pkinase PF00069.20 EIW71847.1 - 2.6e-59 200.5 0.0 5.7e-57 192.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71847.1 - 2.7e-25 88.8 0.0 1.7e-24 86.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW71847.1 - 8.3e-07 28.2 0.0 9.9e-07 27.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PIF1 PF05970.9 EIW71848.1 - 7.1e-113 377.2 0.0 9.8e-113 376.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIW71848.1 - 1.3e-05 24.8 0.0 4.7e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EIW71848.1 - 0.0001 20.2 0.0 0.00018 19.4 0.0 1.3 1 0 0 1 1 1 1 Helicase AAA_19 PF13245.1 EIW71848.1 - 0.00047 19.8 0.5 0.018 14.7 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 EIW71848.1 - 0.0024 18.0 0.0 0.0079 16.3 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DAP3 PF10236.4 EIW71848.1 - 0.065 12.1 0.0 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Viral_helicase1 PF01443.13 EIW71848.1 - 0.067 12.6 0.3 1.8 8.0 0.0 2.5 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Helitron_like_N PF14214.1 EIW71849.1 - 3.5e-19 69.2 0.0 7.3e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus FHA PF00498.21 EIW71850.1 - 6.6e-08 32.5 0.1 1.7e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 FHA domain Mis12 PF05859.7 EIW71852.1 - 3.5e-18 65.8 0.0 6.6e-18 64.9 0.0 1.4 1 1 0 1 1 1 1 Mis12 protein DUF1664 PF07889.7 EIW71852.1 - 0.02 14.6 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Exonuc_VII_S PF02609.11 EIW71852.1 - 0.059 13.1 0.2 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Exonuclease VII small subunit WD40 PF00400.27 EIW71853.1 - 1e-42 142.5 19.2 1.4e-08 34.3 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Hira PF07569.6 EIW71853.1 - 1.1e-24 86.9 0.0 4e-24 85.0 0.0 1.9 1 1 0 1 1 1 1 TUP1-like enhancer of split Nbas_N PF15492.1 EIW71853.1 - 0.049 12.7 0.1 6.8 5.6 0.0 3.2 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DDE_Tnp_4 PF13359.1 EIW71855.1 - 8.2e-14 51.4 0.1 1e-13 51.2 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EIW71855.1 - 0.002 17.7 0.1 0.042 13.3 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 EIW71855.1 - 0.0026 17.1 0.1 0.0032 16.8 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Myb_DNA-bind_4 PF13837.1 EIW71855.1 - 0.061 13.4 0.2 0.097 12.8 0.1 1.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Lipase_GDSL_2 PF13472.1 EIW71857.1 - 8.7e-18 65.0 0.1 1.5e-17 64.3 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DDE_3 PF13358.1 EIW71861.1 - 1.3e-18 67.1 0.0 2.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIW71861.1 - 2.5e-09 37.0 0.6 5.9e-09 35.8 0.4 1.6 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 EIW71861.1 - 1.5e-06 28.3 1.7 1.5e-05 25.1 0.2 2.4 1 1 1 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 EIW71861.1 - 1.7e-06 27.4 2.8 0.00039 19.9 0.1 2.8 2 0 0 2 2 2 2 Homeodomain-like domain MarR_2 PF12802.2 EIW71861.1 - 6.2e-06 25.7 0.0 0.0052 16.4 0.0 2.7 2 0 0 2 2 2 2 MarR family HTH_28 PF13518.1 EIW71861.1 - 8.6e-06 25.6 2.8 0.0047 16.8 0.2 3.1 2 1 1 3 3 3 2 Helix-turn-helix domain HTH_38 PF13936.1 EIW71861.1 - 0.00019 20.9 0.3 0.0036 16.8 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.5 EIW71861.1 - 0.00032 20.2 0.0 0.0042 16.6 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.11 EIW71861.1 - 0.00094 18.4 0.1 0.87 8.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_20 PF12840.2 EIW71861.1 - 0.0034 17.1 0.0 0.076 12.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.1 EIW71861.1 - 0.0036 16.6 0.0 0.92 8.9 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 EIW71861.1 - 0.0055 16.2 0.0 1.6 8.2 0.0 2.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Terminase_5 PF06056.7 EIW71861.1 - 0.012 15.1 0.1 0.074 12.6 0.0 2.2 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_32 PF13565.1 EIW71861.1 - 0.015 16.1 6.9 0.03 15.0 3.2 2.5 1 1 1 2 2 2 0 Homeodomain-like domain HTH_31 PF13560.1 EIW71861.1 - 0.071 13.3 0.3 0.26 11.5 0.0 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.2 EIW71861.1 - 0.12 12.6 0.2 23 5.3 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EIW71861.1 - 0.13 11.7 0.0 0.58 9.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.17 EIW71861.1 - 0.15 11.9 0.1 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix AAA PF00004.24 EIW71865.1 - 7e-20 71.5 0.0 1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW71865.1 - 0.0024 17.9 0.2 0.078 13.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EIW71865.1 - 0.016 14.9 0.1 0.066 12.9 0.0 1.9 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EIW71865.1 - 0.058 13.2 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW71865.1 - 0.064 14.0 0.0 0.22 12.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EIW71865.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain YHS PF04945.8 EIW71866.1 - 0.064 13.1 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 YHS domain Cytochrome_CBB3 PF13442.1 EIW71869.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF678 PF05077.7 EIW71870.1 - 0.11 12.4 0.1 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DCR PF14047.1 EIW71870.1 - 1.6 9.0 4.4 7.3 6.9 0.7 2.4 2 0 0 2 2 2 0 Dppa2/4 conserved region Sex_peptide PF08138.6 EIW71872.1 - 0.067 13.0 0.0 0.49 10.2 0.0 2.6 2 0 0 2 2 2 0 Sex peptide (SP) family Peptidase_A22B PF04258.8 EIW71872.1 - 0.19 11.1 5.7 0.17 11.3 0.1 2.8 2 2 0 2 2 2 0 Signal peptide peptidase Nrap PF03813.9 EIW71873.1 - 9.3e-235 781.4 0.0 1.1e-234 781.2 0.0 1.0 1 0 0 1 1 1 1 Nrap protein DNA_pol_B_palm PF14792.1 EIW71873.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm Octopine_DH PF02317.12 EIW71873.1 - 0.17 11.5 0.0 0.52 9.9 0.0 1.7 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F-box-like PF12937.2 EIW71876.1 - 4.9e-05 22.9 1.0 4.9e-05 22.9 0.7 2.1 3 0 0 3 3 3 1 F-box-like MitMem_reg PF13012.1 EIW71877.1 - 5e-29 100.7 0.0 8.3e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EIW71877.1 - 9.9e-23 80.0 0.0 1.6e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease EspA PF03433.8 EIW71877.1 - 0.11 11.8 0.7 0.21 11.0 0.5 1.4 1 0 0 1 1 1 0 EspA-like secreted protein BCDHK_Adom3 PF10436.4 EIW71878.1 - 2.5e-65 218.9 0.0 3.5e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIW71878.1 - 7.6e-18 64.2 0.0 1.7e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIW71878.1 - 0.0012 18.4 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Alg14 PF08660.6 EIW71879.1 - 8.9e-52 175.5 0.0 1.1e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like ARPC4 PF05856.7 EIW71880.1 - 7e-75 250.0 2.1 7.8e-75 249.9 1.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FKBP_C PF00254.23 EIW71881.1 - 3.9e-29 100.5 0.0 1.5e-28 98.6 0.0 2.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Chromo PF00385.19 EIW71884.1 - 3.3e-14 52.3 0.1 7.5e-14 51.1 0.0 1.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Cu-oxidase_2 PF07731.9 EIW71885.1 - 1e-35 122.2 1.1 1e-35 122.2 0.8 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIW71885.1 - 5.7e-35 119.6 1.9 2e-29 101.6 0.7 3.5 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EIW71885.1 - 2.6e-33 115.1 2.9 6.2e-31 107.4 0.6 3.3 3 0 0 3 3 3 1 Multicopper oxidase DUF165 PF02592.10 EIW71886.1 - 0.11 12.7 11.2 0.4 10.8 7.8 1.9 1 1 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 CcmE PF03100.10 EIW71886.1 - 0.12 11.9 0.1 23 4.5 0.0 2.7 1 1 3 4 4 4 0 CcmE OpcA PF07239.6 EIW71886.1 - 0.13 11.1 1.6 2.7 6.8 0.2 2.5 1 1 2 3 3 3 0 Outer membrane protein OpcA Ldr_toxin PF13940.1 EIW71886.1 - 0.17 11.6 11.5 2.2 8.1 0.5 4.3 1 1 3 4 4 4 0 Toxin Ldr, type I toxin-antitoxin system DUF92 PF01940.11 EIW71886.1 - 1.7 7.7 18.9 35 3.4 13.2 2.1 1 1 0 1 1 1 0 Integral membrane protein DUF92 Yip1 PF04893.12 EIW71886.1 - 2.7 7.4 21.6 4.3 6.7 15.0 1.3 1 0 0 1 1 1 0 Yip1 domain Doppel PF11466.3 EIW71886.1 - 6.8 6.3 36.5 1.8 8.2 1.5 5.9 1 1 5 6 6 6 0 Prion-like protein Doppel YqhR PF11085.3 EIW71886.1 - 7.8 5.9 11.2 33 3.9 7.8 1.9 1 1 0 1 1 1 0 Conserved membrane protein YqhR ANTH PF07651.11 EIW71887.1 - 1.4e-44 151.9 0.0 1.7e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.6 EIW71887.1 - 4.3e-06 26.6 32.0 4.3e-06 26.6 22.2 7.0 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) Retrotrans_gag PF03732.12 EIW71891.1 - 8.4e-06 25.7 0.1 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIW71893.1 - 0.003 17.4 1.9 0.0056 16.5 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.9 EIW71894.1 - 1.8e-25 89.3 0.0 1.9e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) KSHV_K8 PF07188.6 EIW71903.1 - 0.0092 15.2 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 1 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein Ribosomal_60s PF00428.14 EIW71903.1 - 0.69 10.3 6.6 1.7 9.1 4.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein NST1 PF13945.1 EIW71905.1 - 3.9 7.5 8.7 1.5 8.8 2.0 2.4 1 1 1 2 2 2 0 Salt tolerance down-regulator Ribosomal_S10 PF00338.17 EIW71906.1 - 4.4e-17 61.7 0.0 4.6e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e OB_RNB PF08206.6 EIW71906.1 - 0.02 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease B OB domain eIF-1a PF01176.14 EIW71906.1 - 0.021 14.2 0.3 0.03 13.7 0.2 1.2 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 SNAP PF14938.1 EIW71907.1 - 4.2e-98 327.9 15.3 4.8e-98 327.7 10.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 EIW71907.1 - 0.0028 17.9 3.9 2.7 8.6 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW71907.1 - 0.005 16.7 6.9 0.042 13.7 0.2 3.2 1 1 0 2 2 2 1 Tetratricopeptide repeat Clathrin PF00637.15 EIW71907.1 - 0.41 10.2 6.7 0.61 9.6 0.3 3.0 3 1 0 3 3 3 0 Region in Clathrin and VPS NSF PF02071.15 EIW71907.1 - 3.2 8.7 11.4 29 5.8 0.2 5.6 6 1 1 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat zf-CCCH PF00642.19 EIW71908.1 - 1.7e-12 46.7 13.1 1.4e-07 30.9 0.8 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EIW71908.1 - 0.024 14.4 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flu_NS1 PF00600.14 EIW71909.1 - 0.066 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) Rad21_Rec8_N PF04825.8 EIW71910.1 - 3.2e-18 65.6 0.0 6.7e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EIW71910.1 - 5.3e-05 22.3 0.0 0.00011 21.3 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Cyclin_N PF00134.18 EIW71913.1 - 5.7e-09 35.6 0.0 1.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 EIW71913.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Transcription factor TFIIB repeat ATG27 PF09451.5 EIW71914.1 - 5.5e-55 186.4 0.0 6.7e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 EIW71914.1 - 0.14 11.1 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor WD40 PF00400.27 EIW71915.1 - 4.6e-13 48.4 18.4 4.3e-05 23.2 0.5 6.3 5 1 0 5 5 5 4 WD domain, G-beta repeat DivIC PF04977.10 EIW71915.1 - 9.8 5.7 10.6 5.8 6.4 0.7 2.5 2 0 0 2 2 2 0 Septum formation initiator DNA_pol_B_palm PF14792.1 EIW71916.1 - 1.1e-28 99.4 0.0 2.7e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EIW71916.1 - 1.5e-20 72.6 0.1 3.7e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 EIW71916.1 - 4.8e-17 61.9 0.3 3.3e-15 56.0 0.0 3.0 2 1 1 3 3 3 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EIW71916.1 - 3.1e-15 55.4 0.0 1.1e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda BRCT PF00533.21 EIW71916.1 - 7.6e-05 22.7 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 EIW71916.1 - 0.016 15.5 0.1 0.039 14.2 0.1 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Cdd1 PF11731.3 EIW71916.1 - 0.074 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus Pyridox_oxidase PF01243.15 EIW71917.1 - 1.6e-08 34.4 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Multi_ubiq PF14452.1 EIW71917.1 - 0.0061 16.5 0.0 0.59 10.1 0.0 2.4 2 0 0 2 2 2 1 Multiubiquitin DUF4309 PF14172.1 EIW71917.1 - 0.025 14.5 0.0 5.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4309) Alpha-E PF04168.7 EIW71920.1 - 0.031 13.6 0.1 0.08 12.3 0.0 1.6 2 0 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. Med27 PF11571.3 EIW71920.1 - 0.15 12.2 0.7 0.43 10.7 0.2 1.9 1 1 1 2 2 2 0 Mediator complex subunit 27 HTH_Tnp_Tc3_2 PF01498.13 EIW71922.1 - 4.9e-10 39.3 0.5 6.4e-10 38.9 0.4 1.2 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.1 EIW71922.1 - 0.015 14.4 0.1 0.042 13.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.1 EIW71922.1 - 0.041 13.8 0.4 1.3 9.0 0.1 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.1 EIW71922.1 - 0.05 13.1 0.0 0.18 11.3 0.0 2.0 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_23 PF13384.1 EIW71922.1 - 0.11 12.1 0.2 0.31 10.7 0.1 1.9 1 1 0 1 1 1 0 Homeodomain-like domain RVT_1 PF00078.22 EIW71926.1 - 1.3e-11 44.2 0.0 2.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 EIW71926.1 - 2e-07 31.3 0.0 4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIW71926.1 - 5e-07 29.4 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EIW71926.1 - 7.8e-05 22.6 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EIW71926.1 - 0.00089 19.1 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EIW71926.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease DUF2587 PF10759.4 EIW71927.1 - 0.044 13.1 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Sod_Fe_C PF02777.13 EIW71928.1 - 3.4e-35 120.0 0.1 5.6e-35 119.3 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EIW71928.1 - 1.8e-32 111.4 0.8 3.6e-32 110.4 0.3 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DIM1 PF02966.11 EIW71929.1 - 3.1e-67 224.1 0.5 3.5e-67 223.9 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EIW71929.1 - 0.0084 15.7 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Ssl1 PF04056.9 EIW71930.1 - 4.8e-58 195.9 0.0 6.8e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EIW71930.1 - 1.4e-15 57.0 9.0 1.4e-15 57.0 6.2 2.3 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EIW71930.1 - 8e-10 39.0 0.0 1.2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain HNH_5 PF14279.1 EIW71930.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.1 3 0 0 3 3 3 0 HNH endonuclease DZR PF12773.2 EIW71930.1 - 3.3 7.6 20.3 0.45 10.3 2.7 3.3 2 1 0 2 2 2 0 Double zinc ribbon IBR PF01485.16 EIW71930.1 - 9.9 6.1 16.0 0.07 13.0 3.1 2.6 2 0 0 2 2 2 0 IBR domain Pkinase PF00069.20 EIW71932.1 - 6.2e-57 192.7 0.0 8.7e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71932.1 - 2.8e-21 75.7 0.1 5.9e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW71932.1 - 0.022 14.5 0.0 0.071 12.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW71932.1 - 0.11 12.0 0.1 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EIW71932.1 - 0.24 10.7 0.0 0.46 9.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2051 PF09738.4 EIW71932.1 - 8.4 5.5 8.8 0.17 11.1 0.3 2.4 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) AAA_17 PF13207.1 EIW71934.1 - 1.9e-05 25.4 0.1 8.7e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW71934.1 - 0.00019 21.7 0.1 0.0011 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW71934.1 - 0.14 11.9 0.0 0.71 9.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF1319 PF07028.6 EIW71935.1 - 0.00014 22.0 1.2 0.00019 21.5 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) Erp_C PF06780.6 EIW71935.1 - 0.00018 21.4 2.4 0.00036 20.3 1.6 1.5 1 1 0 1 1 1 1 Erp protein C-terminus Reo_sigmaC PF04582.7 EIW71935.1 - 0.0032 16.6 1.4 0.0037 16.5 1.0 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF1664 PF07889.7 EIW71935.1 - 0.0072 16.1 3.2 0.012 15.3 2.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Spc7 PF08317.6 EIW71935.1 - 0.008 14.8 2.6 0.0086 14.7 1.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein V-SNARE PF05008.10 EIW71935.1 - 0.0089 16.1 2.3 0.25 11.5 1.6 2.2 1 1 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus MscS_porin PF12795.2 EIW71935.1 - 0.012 14.9 2.9 0.014 14.7 2.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.7 EIW71935.1 - 0.02 14.7 2.5 0.028 14.2 1.7 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EIW71935.1 - 0.021 15.0 4.3 0.025 14.7 1.9 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 EIW71935.1 - 0.021 14.6 2.5 0.026 14.3 1.7 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EIW71935.1 - 0.028 12.9 5.0 0.035 12.5 3.5 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Laminin_II PF06009.7 EIW71935.1 - 0.039 13.7 2.5 0.057 13.1 1.7 1.3 1 0 0 1 1 1 0 Laminin Domain II Sec8_exocyst PF04048.9 EIW71935.1 - 0.051 13.1 4.4 0.032 13.8 1.9 1.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF2730 PF10805.3 EIW71935.1 - 0.07 12.8 3.0 0.29 10.8 2.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) Fmp27_WPPW PF10359.4 EIW71935.1 - 0.073 11.4 1.6 0.085 11.2 1.1 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cob_adeno_trans PF01923.13 EIW71935.1 - 0.091 12.5 0.3 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IncA PF04156.9 EIW71935.1 - 0.21 11.1 4.8 0.25 10.9 3.3 1.1 1 0 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 EIW71935.1 - 1.6 8.6 5.9 2.3 8.1 1.7 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Peptidase_S13 PF02113.10 EIW71936.1 - 0.033 12.6 0.0 0.054 12.0 0.0 1.2 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family HEAT_2 PF13646.1 EIW71936.1 - 0.035 14.3 1.5 5.1 7.4 0.1 3.9 2 1 1 3 3 3 0 HEAT repeats Arm PF00514.18 EIW71936.1 - 0.061 13.1 14.1 0.26 11.1 0.1 5.4 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat HECT PF00632.20 EIW71937.1 - 4.3e-96 321.8 0.0 6.7e-96 321.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EIW71937.1 - 2.2e-54 184.9 1.6 4.2e-54 184.0 1.1 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 EIW71937.1 - 4e-52 177.2 0.9 9.6e-45 152.9 0.0 3.8 3 1 1 4 4 4 2 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 EIW71937.1 - 7.4e-19 67.6 5.3 2.3e-18 66.0 3.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) UBA PF00627.26 EIW71937.1 - 2e-06 27.4 0.1 1e-05 25.2 0.0 2.4 1 0 0 1 1 1 1 UBA/TS-N domain Stc1 PF12898.2 EIW71938.1 - 0.044 13.8 0.3 0.068 13.2 0.2 1.3 1 0 0 1 1 1 0 Stc1 domain DUF591 PF04569.9 EIW71940.1 - 2.3 8.3 6.7 0.59 10.2 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function WD40 PF00400.27 EIW71941.1 - 1.1e-46 155.0 16.9 1.4e-09 37.4 0.6 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EIW71941.1 - 0.003 17.2 6.6 3.1 7.4 0.0 4.2 3 1 1 4 4 4 2 Transcription factor IIIC subunit delta N-term Kelch_2 PF07646.10 EIW71941.1 - 5.8 6.8 6.6 2.5 8.0 0.0 3.2 4 0 0 4 4 4 0 Kelch motif Racemase_4 PF13615.1 EIW71942.1 - 5.3e-12 45.8 0.3 1.1e-11 44.8 0.2 1.6 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 EIW71942.1 - 2.5e-06 27.0 0.0 8.3e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor ATP-synt_ab PF00006.20 EIW71943.1 - 4e-62 209.5 0.0 5.3e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIW71943.1 - 2.6e-16 60.0 0.0 5.1e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIW71943.1 - 1.2e-09 38.1 0.4 2.4e-09 37.2 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EIW71943.1 - 0.0087 15.9 0.1 0.023 14.5 0.1 1.7 1 0 0 1 1 1 1 HAS barrel domain Ala_racemase_N PF01168.15 EIW71944.1 - 2.8e-42 144.7 0.0 3.3e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Flg_hook PF02120.11 EIW71944.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Lipoprotein_8 PF02030.10 EIW71944.1 - 0.15 10.5 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) SF3b1 PF08920.5 EIW71945.1 - 1.9e-19 70.1 9.8 1.3e-18 67.4 6.8 2.9 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EIW71945.1 - 1.1e-16 60.8 6.3 2.1e-05 24.7 0.0 7.8 7 2 1 9 9 9 4 HEAT repeats HEAT_EZ PF13513.1 EIW71945.1 - 1.6e-14 53.8 10.0 0.029 14.8 0.0 9.5 8 2 2 10 10 10 3 HEAT-like repeat HEAT PF02985.17 EIW71945.1 - 5.1e-09 35.4 15.5 0.1 12.7 0.1 10.7 13 0 0 13 13 13 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EIW71945.1 - 1.4e-08 34.9 0.6 0.31 11.4 0.0 5.3 6 0 0 6 6 6 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EIW71945.1 - 5e-06 25.1 0.0 0.0068 14.7 0.0 3.2 1 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 EIW71945.1 - 0.0041 16.5 0.3 0.39 10.0 0.0 2.8 2 0 0 2 2 2 1 CLASP N terminal RIX1 PF08167.7 EIW71945.1 - 0.067 12.8 0.0 6.2 6.4 0.0 3.6 3 1 0 4 4 4 0 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EIW71945.1 - 0.098 11.3 0.0 3.5 6.2 0.0 3.4 3 2 0 3 3 3 0 RNAPII transcription regulator C-terminal Choline_kinase PF01633.15 EIW71946.1 - 1.7e-49 168.2 0.0 2.4e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EIW71946.1 - 6.1e-12 45.7 1.0 1.1e-11 44.9 0.7 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_cc PF11790.3 EIW71947.1 - 4.1e-56 190.0 0.4 5.3e-56 189.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Sec10 PF07393.6 EIW71948.1 - 3.5e-145 485.0 0.0 4.2e-145 484.7 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EIW71948.1 - 0.00031 20.4 0.0 0.0011 18.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW71948.1 - 0.00048 19.6 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.11 EIW71949.1 - 1.9e-20 72.9 31.3 1.6e-17 63.2 6.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW71949.1 - 3.6e-07 29.1 3.6 3.6e-07 29.1 2.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EIW71949.1 - 0.24 11.2 5.5 0.22 11.3 0.1 2.9 3 0 0 3 3 3 0 MFS_1 like family Put_Phosphatase PF06888.7 EIW71950.1 - 2.7e-46 157.6 0.0 3.1e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 EIW71950.1 - 0.00014 22.1 0.0 0.0011 19.2 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW71950.1 - 0.1 12.7 0.2 0.15 12.2 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase L51_S25_CI-B8 PF05047.11 EIW71951.1 - 6.6e-11 41.7 0.0 9.3e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Arrestin_N PF00339.24 EIW71952.1 - 1.1e-13 51.2 0.4 5.8e-13 48.8 0.0 2.4 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIW71952.1 - 3.9e-11 43.1 8.6 5.1e-10 39.5 5.9 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EIW71952.1 - 3.4e-05 23.4 0.0 6.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like GDPD PF03009.12 EIW71953.1 - 7.1e-32 110.9 0.0 1.5e-31 109.8 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EIW71953.1 - 0.0096 16.0 0.5 0.19 11.9 0.0 2.7 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Acyltransferase PF01553.16 EIW71954.1 - 2.3e-16 59.4 0.0 3.7e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Nterm_IS4 PF13006.2 EIW71954.1 - 0.048 13.6 0.1 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal TSNR_N PF04705.7 EIW71954.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus SRP40_C PF05022.7 EIW71955.1 - 2.5e-28 98.3 1.9 3.6e-28 97.8 1.3 1.2 1 0 0 1 1 1 1 SRP40, C-terminal domain RSF PF14876.1 EIW71955.1 - 0.017 13.9 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator PRCC PF10253.4 EIW71955.1 - 0.46 11.1 4.1 0.5 11.0 2.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MDM1 PF15501.1 EIW71955.1 - 0.63 8.9 9.8 0.59 9.0 6.8 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Chorion_2 PF03964.10 EIW71955.1 - 1.3 9.6 10.3 0.42 11.1 4.9 1.8 2 0 0 2 2 2 0 Chorion family 2 FAM117 PF15388.1 EIW71955.1 - 1.3 8.1 14.2 1.7 7.8 9.8 1.1 1 0 0 1 1 1 0 Protein Family FAM117 AA_kinase PF00696.23 EIW71956.1 - 1.2e-30 106.8 0.0 2.2e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 EIW71956.1 - 6.1e-12 44.8 1.6 6.2e-07 28.8 0.1 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EIW71956.1 - 1.8e-11 43.2 0.4 0.00016 21.1 0.0 2.6 2 0 0 2 2 2 2 ACT domain FimP PF09766.4 EIW71957.1 - 8.1e-12 44.8 0.5 9.4e-12 44.6 0.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein DUF4201 PF13870.1 EIW71957.1 - 0.035 13.5 3.7 0.46 9.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.7 EIW71957.1 - 0.11 12.2 2.1 0.17 11.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Med21 PF11221.3 EIW71957.1 - 0.29 11.1 5.5 1 9.2 0.2 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DUF3006 PF11213.3 EIW71957.1 - 0.44 10.3 4.1 1.1 9.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) BicD PF09730.4 EIW71957.1 - 0.45 8.8 4.3 0.21 9.8 0.1 1.8 1 1 0 2 2 2 0 Microtubule-associated protein Bicaudal-D LysM PF01476.15 EIW71958.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 LysM domain Apc4 PF12896.2 EIW71959.1 - 2.3e-18 66.2 0.0 5.9e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 PhyH PF05721.8 EIW71960.1 - 0.13 12.3 0.1 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) zf-H2C2_2 PF13465.1 EIW71961.1 - 6.9e-06 26.0 0.9 6.9e-06 26.0 0.6 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 EIW71961.1 - 3.6e-05 23.8 7.4 0.00011 22.2 1.2 3.5 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW71961.1 - 8.5e-05 22.6 11.8 0.0004 20.5 0.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW71961.1 - 0.00064 19.7 5.2 0.13 12.4 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EIW71961.1 - 0.015 15.6 4.9 0.017 15.5 1.6 2.1 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_6 PF13912.1 EIW71961.1 - 0.027 14.3 8.0 0.085 12.7 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Ogr_Delta PF04606.7 EIW71961.1 - 0.17 11.6 0.2 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger zf-C2H2_2 PF12756.2 EIW71961.1 - 4.9 7.3 5.1 10 6.3 0.2 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Aldedh PF00171.17 EIW71962.1 - 3e-127 424.7 0.1 3.5e-127 424.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW71962.1 - 2.7e-05 23.0 0.0 4.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF4325 PF14213.1 EIW71962.1 - 0.17 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) Clathrin PF00637.15 EIW71963.1 - 8.9e-28 96.6 0.3 1.8e-27 95.6 0.2 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_1 PF10366.4 EIW71963.1 - 1.4e-05 25.0 0.2 0.021 14.8 0.0 2.7 1 1 1 2 2 2 2 Vacuolar sorting protein 39 domain 1 WD40 PF00400.27 EIW71963.1 - 0.0078 16.0 0.0 0.23 11.3 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF1499 PF07386.6 EIW71963.1 - 0.015 15.4 0.2 0.35 11.0 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1499) Methyltransf_23 PF13489.1 EIW71965.1 - 0.0052 16.5 0.0 0.029 14.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain DUF1664 PF07889.7 EIW71968.1 - 0.021 14.6 0.9 1.7 8.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tet_JBP PF12851.2 EIW71972.1 - 1.9e-08 33.7 0.0 3.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EIW71972.1 - 5.9e-05 23.5 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW71972.1 - 0.053 13.8 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily UFC1 PF08694.6 EIW71973.1 - 0.1 12.0 0.1 0.83 9.1 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 DDE_3 PF13358.1 EIW71974.1 - 1.5e-18 66.9 0.0 2.7e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIW71974.1 - 2.6e-09 37.0 0.6 6.2e-09 35.8 0.4 1.7 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.1 EIW71974.1 - 1.7e-07 30.6 0.7 0.00014 21.3 0.0 2.8 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 EIW71974.1 - 2.5e-07 30.8 1.1 3.3e-06 27.2 0.1 2.3 1 1 1 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 EIW71974.1 - 1e-06 28.5 1.4 0.0012 18.7 0.1 3.0 2 1 1 3 3 3 2 Helix-turn-helix domain MarR_2 PF12802.2 EIW71974.1 - 7.4e-06 25.5 0.0 0.0057 16.2 0.0 2.7 2 0 0 2 2 2 2 MarR family HTH_IclR PF09339.5 EIW71974.1 - 9.2e-05 21.9 0.0 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_38 PF13936.1 EIW71974.1 - 0.0002 20.8 0.2 0.0037 16.7 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 EIW71974.1 - 0.00049 19.3 0.0 0.43 9.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_24 PF13412.1 EIW71974.1 - 0.00054 19.2 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 EIW71974.1 - 0.0015 18.0 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_20 PF12840.2 EIW71974.1 - 0.0018 18.0 0.0 0.039 13.7 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EIW71974.1 - 0.0026 18.4 5.3 0.011 16.5 2.8 2.4 1 1 1 2 2 2 1 Homeodomain-like domain Terminase_5 PF06056.7 EIW71974.1 - 0.011 15.2 0.1 0.069 12.7 0.0 2.2 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) DUF3489 PF11994.3 EIW71974.1 - 0.032 14.1 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Sigma70_r4_2 PF08281.7 EIW71974.1 - 0.036 13.5 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 DUF2587 PF10759.4 EIW71975.1 - 0.049 13.0 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) BUD22 PF09073.5 EIW71976.1 - 7.1 5.5 11.3 13 4.6 7.8 1.3 1 0 0 1 1 1 0 BUD22 DUF2353 PF09789.4 EIW71980.1 - 0.00062 19.1 10.6 0.044 13.0 0.9 2.1 1 1 1 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) Cep57_MT_bd PF06657.8 EIW71980.1 - 0.0012 18.7 3.5 0.0072 16.2 0.1 2.7 1 1 2 3 3 3 1 Centrosome microtubule-binding domain of Cep57 IncA PF04156.9 EIW71980.1 - 0.0057 16.2 13.6 0.066 12.7 9.4 2.0 1 1 0 1 1 1 1 IncA protein bZIP_1 PF00170.16 EIW71980.1 - 0.0072 16.2 4.3 0.31 11.0 0.1 3.5 2 1 2 4 4 4 1 bZIP transcription factor DUF904 PF06005.7 EIW71980.1 - 0.0096 16.1 8.3 0.33 11.2 1.4 2.9 1 1 1 2 2 2 1 Protein of unknown function (DUF904) BLOC1_2 PF10046.4 EIW71980.1 - 0.0096 16.0 1.3 0.12 12.4 0.2 2.3 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 EIW71980.1 - 0.017 15.4 4.1 0.39 11.0 0.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Sec34 PF04136.10 EIW71980.1 - 0.019 14.6 3.9 1.1 8.9 0.8 2.2 2 0 0 2 2 2 0 Sec34-like family Herpes_UL6 PF01763.11 EIW71980.1 - 0.054 11.6 3.7 0.064 11.4 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Taxilin PF09728.4 EIW71980.1 - 0.062 12.3 6.2 0.055 12.5 3.1 1.7 1 1 1 2 2 2 0 Myosin-like coiled-coil protein HALZ PF02183.13 EIW71980.1 - 0.063 13.0 7.3 0.64 9.7 0.3 3.4 2 1 2 4 4 3 0 Homeobox associated leucine zipper Uso1_p115_C PF04871.8 EIW71980.1 - 0.073 13.0 5.6 0.058 13.3 1.9 1.9 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CCDC155 PF14662.1 EIW71980.1 - 0.082 12.4 8.8 0.16 11.5 6.1 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Spc7 PF08317.6 EIW71980.1 - 0.15 10.7 7.2 0.31 9.6 5.0 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 EIW71980.1 - 0.16 11.4 4.8 6.1 6.3 2.2 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EIW71980.1 - 0.17 11.6 7.8 2.3 7.9 1.4 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EIW71980.1 - 0.17 10.8 7.9 0.41 9.6 5.5 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 Mod_r PF07200.8 EIW71980.1 - 0.18 11.7 5.5 0.31 10.9 3.3 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein WEMBL PF05701.6 EIW71980.1 - 0.2 10.0 6.2 0.26 9.7 4.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CorA PF01544.13 EIW71980.1 - 0.31 10.0 7.0 3.8 6.4 6.3 1.8 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Hemerythrin PF01814.18 EIW71980.1 - 0.33 11.1 4.6 22 5.1 0.0 2.8 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain CENP-F_leu_zip PF10473.4 EIW71980.1 - 0.33 10.7 10.4 0.99 9.2 1.9 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 EIW71980.1 - 0.5 10.2 1.9 18 5.3 0.0 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 EIW71980.1 - 0.54 10.1 5.8 0.91 9.3 1.3 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4613 PF15390.1 EIW71980.1 - 0.56 8.3 2.4 3.1 5.8 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4613) DivIC PF04977.10 EIW71980.1 - 0.66 9.4 6.0 4.2 6.9 0.4 3.1 2 1 1 3 3 3 0 Septum formation initiator Syntaxin-6_N PF09177.6 EIW71980.1 - 0.73 10.2 8.4 18 5.8 0.1 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal H-kinase_dim PF02895.9 EIW71980.1 - 1.1 9.6 8.9 0.046 14.0 1.3 2.1 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain GAS PF13851.1 EIW71980.1 - 1.3 8.1 6.6 3.7 6.6 4.3 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 EIW71980.1 - 1.5 8.6 12.9 1.4 8.6 5.5 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Syntaxin PF00804.20 EIW71980.1 - 2.3 8.4 6.2 20 5.3 4.3 2.2 1 1 0 1 1 1 0 Syntaxin TSC22 PF01166.13 EIW71980.1 - 2.3 8.2 5.0 6.7 6.7 0.8 3.4 1 1 3 4 4 4 0 TSC-22/dip/bun family Nnf1 PF03980.9 EIW71980.1 - 2.6 8.0 8.1 14 5.7 1.6 2.3 1 1 1 2 2 2 0 Nnf1 DUF2205 PF10224.4 EIW71980.1 - 2.7 7.6 8.6 0.84 9.2 2.3 2.6 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) Atg14 PF10186.4 EIW71980.1 - 3.9 6.3 7.3 6.7 5.5 4.8 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 EIW71980.1 - 5.7 4.6 4.8 9.8 3.8 3.4 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 EIW71980.1 - 7.1 6.5 6.7 7.1 6.5 0.3 3.3 3 1 2 5 5 4 0 Basic region leucine zipper Glyco_hydro_18 PF00704.23 EIW71982.1 - 8.3e-56 189.8 2.6 9.4e-56 189.7 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RNase_HII PF01351.13 EIW71984.1 - 4.1e-43 147.3 0.0 9e-43 146.2 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease HII CBF PF03914.12 EIW71985.1 - 6.3e-24 84.2 2.7 1e-23 83.5 0.0 2.5 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 EIW71985.1 - 3e-16 59.4 0.0 3e-16 59.4 0.0 2.9 2 2 1 3 3 3 1 Nucleolar complex-associated protein RP-C_C PF11800.3 EIW71985.1 - 0.0016 18.1 1.7 0.0016 18.1 1.2 2.4 3 0 0 3 3 3 1 Replication protein C C-terminal region Neur_chan_memb PF02932.11 EIW71985.1 - 0.3 10.9 2.0 0.84 9.4 1.4 1.8 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.5 EIW71985.1 - 0.56 9.9 8.1 2.1 8.1 5.6 2.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SAE2 PF08573.5 EIW71988.1 - 1.1e-20 74.1 2.1 1.1e-20 74.1 1.4 1.8 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Macoilin PF09726.4 EIW71989.1 - 0.00076 17.9 18.7 0.00076 17.9 13.0 2.8 2 1 0 2 2 1 1 Transmembrane protein NUDE_C PF04880.8 EIW71989.1 - 0.002 18.5 30.7 0.002 18.5 21.3 5.9 3 2 0 4 4 2 1 NUDE protein, C-terminal conserved region BicD PF09730.4 EIW71989.1 - 0.0039 15.6 10.2 0.0039 15.6 7.1 2.3 1 1 1 2 2 2 2 Microtubule-associated protein Bicaudal-D DUF904 PF06005.7 EIW71989.1 - 0.016 15.5 6.7 0.016 15.5 4.6 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF904) ERM PF00769.14 EIW71989.1 - 0.03 13.8 27.8 0.22 11.0 10.3 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Syntaxin-6_N PF09177.6 EIW71989.1 - 0.082 13.3 11.4 0.88 10.0 3.1 3.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF3584 PF12128.3 EIW71989.1 - 0.16 9.2 22.4 0.24 8.6 15.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DivIC PF04977.10 EIW71989.1 - 5.1 6.6 22.2 2.3 7.7 4.5 3.7 2 1 2 4 4 4 0 Septum formation initiator DUF342 PF03961.8 EIW71989.1 - 5.2 5.3 17.6 1.5 7.1 6.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Spc24 PF08286.6 EIW71989.1 - 6.6 6.4 21.3 0.44 10.2 5.2 3.3 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 TBPIP PF07106.8 EIW71989.1 - 9.1 5.7 26.7 0.79 9.2 8.4 2.7 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EIW71989.1 - 9.7 5.1 29.2 2.9 6.8 8.1 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 BRE1 PF08647.6 EIW71990.1 - 5.6e-19 67.9 6.5 5.6e-19 67.9 4.5 5.5 4 2 1 5 5 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.20 EIW71990.1 - 7.1e-05 22.3 14.3 0.00012 21.6 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW71990.1 - 9e-05 22.4 13.5 0.00016 21.5 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW71990.1 - 0.00031 20.3 11.3 0.00053 19.5 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EIW71990.1 - 0.00044 19.9 4.3 0.00086 19.0 3.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Macoilin PF09726.4 EIW71990.1 - 0.0036 15.6 2.6 0.0036 15.6 1.8 3.7 2 1 0 3 3 2 1 Transmembrane protein APG6 PF04111.7 EIW71990.1 - 0.0037 16.3 4.2 0.0037 16.3 2.9 5.1 3 3 2 5 5 4 2 Autophagy protein Apg6 zf-RING_2 PF13639.1 EIW71990.1 - 0.0074 16.1 11.0 0.015 15.1 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain DUF2893 PF11459.3 EIW71990.1 - 0.0087 15.8 0.0 0.032 14.0 0.0 2.0 1 0 0 1 1 1 1 Protein of unknwon function (DUF2893) zf-RING_5 PF14634.1 EIW71990.1 - 0.0095 15.6 13.4 0.017 14.8 9.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Rootletin PF15035.1 EIW71990.1 - 0.011 15.6 4.6 0.011 15.6 3.2 5.9 4 2 2 6 6 4 0 Ciliary rootlet component, centrosome cohesion Met_synt_B12 PF02965.12 EIW71990.1 - 0.027 13.6 0.1 0.067 12.3 0.1 1.6 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain Prok-RING_4 PF14447.1 EIW71990.1 - 0.2 11.2 4.3 0.39 10.2 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FlaC_arch PF05377.6 EIW71990.1 - 0.81 9.6 5.0 19 5.2 0.2 4.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) zf-RING_4 PF14570.1 EIW71990.1 - 2.2 7.9 10.0 4.8 6.8 6.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EIW71990.1 - 5.3 7.0 11.3 9.8 6.1 7.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Glyco_tranf_2_3 PF13641.1 EIW71992.1 - 1.7e-22 80.3 0.0 2.7e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIW71992.1 - 1.6e-08 34.4 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIW71992.1 - 7e-08 31.9 0.0 1.7e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 EIW71992.1 - 0.012 13.9 2.6 0.066 11.5 1.8 1.8 1 1 0 1 1 1 0 Chitin synthase DUF4240 PF14024.1 EIW71992.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) Uricase PF01014.13 EIW71993.1 - 3.6e-62 208.5 0.1 4.2e-34 117.5 0.4 2.0 2 0 0 2 2 2 2 Uricase 3HCDH_N PF02737.13 EIW71994.1 - 4.2e-59 199.2 0.2 5.8e-59 198.7 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EIW71994.1 - 3.6e-32 110.6 0.0 6.7e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EIW71994.1 - 2.5e-05 24.0 0.1 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EIW71994.1 - 0.0019 18.0 1.0 0.0077 16.0 0.4 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIW71994.1 - 0.0027 17.1 0.2 0.0055 16.1 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.1 EIW71994.1 - 0.06 13.1 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 EIW71994.1 - 1 9.8 3.5 15 6.1 2.4 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RNA_pol_Rpb8 PF03870.10 EIW71996.1 - 1.4e-32 112.7 1.0 3.2e-31 108.3 0.7 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb8 ATP-synt_S1 PF05827.7 EIW71997.1 - 0.017 14.4 0.0 1.1 8.4 0.0 2.1 1 1 1 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF3143 PF11341.3 EIW71997.1 - 0.097 12.5 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3143) PWWP PF00855.12 EIW71998.1 - 4.6e-18 65.2 0.0 1.7e-17 63.4 0.0 2.0 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.6 EIW71998.1 - 0.00031 20.1 0.2 0.00059 19.2 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.20 EIW71999.1 - 1.2e-66 224.5 0.0 1.4e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW71999.1 - 2e-29 102.4 0.0 2.8e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW71999.1 - 0.00055 18.9 0.0 0.011 14.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIW71999.1 - 0.014 15.1 0.1 0.078 12.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EIW71999.1 - 0.12 11.3 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pmp3 PF01679.12 EIW72000.1 - 2.1e-14 52.9 4.8 2.9e-14 52.4 3.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MARVEL PF01284.18 EIW72001.1 - 3.2 7.5 23.9 0.32 10.8 2.2 3.4 2 1 1 3 3 3 0 Membrane-associating domain MRP-L47 PF06984.8 EIW72002.1 - 3.6e-20 71.6 1.1 8.2e-20 70.5 0.8 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 EIW72002.1 - 0.18 11.5 1.1 1.4 8.6 0.6 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein DUF566 PF04484.7 EIW72002.1 - 1.7 8.0 9.7 3 7.2 6.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) bZIP_C PF12498.3 EIW72002.1 - 5.2 8.3 13.3 20 6.4 0.0 2.7 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Got1 PF04178.7 EIW72003.1 - 4.8e-11 42.7 10.0 5.2e-11 42.6 7.0 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2632 PF10943.3 EIW72003.1 - 0.88 9.0 8.8 26 4.2 6.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2632) SID-1_RNA_chan PF13965.1 EIW72003.1 - 1.5 6.8 5.9 1.7 6.7 4.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2614 PF11023.3 EIW72003.1 - 1.5 8.6 4.9 1.8 8.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) Adeno_E3B PF03376.9 EIW72003.1 - 2.2 8.2 8.1 2.8 7.9 5.6 1.3 1 0 0 1 1 1 0 Adenovirus E3B protein MIP-T3 PF10243.4 EIW72004.1 - 0.00069 18.2 19.2 0.00069 18.2 13.3 1.6 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 EIW72004.1 - 0.16 11.3 13.5 0.24 10.7 9.3 1.2 1 0 0 1 1 1 0 Vta1 like NLE PF08154.7 EIW72004.1 - 0.17 11.9 0.0 0.45 10.5 0.0 1.7 1 1 1 2 2 2 0 NLE (NUC135) domain NDUF_B12 PF08122.7 EIW72005.1 - 8.8e-20 70.1 0.3 1e-19 69.9 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Cation_ATPase_C PF00689.16 EIW72005.1 - 0.12 11.9 0.0 0.13 11.7 0.0 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus SDH_alpha PF03313.10 EIW72006.1 - 2 7.3 4.9 3.1 6.7 3.4 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain FUSC PF04632.7 EIW72006.1 - 2.6 6.3 2.8 2.4 6.4 1.3 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF4337 PF14235.1 EIW72006.1 - 4.3 7.1 17.4 0.023 14.5 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF972 PF06156.8 EIW72006.1 - 4.6 7.6 16.3 2.4 8.5 4.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TMCO5 PF14992.1 EIW72006.1 - 4.7 6.2 15.9 7.7 5.5 11.0 1.2 1 0 0 1 1 1 0 TMCO5 family Macoilin PF09726.4 EIW72006.1 - 6.6 4.8 24.6 0.0073 14.6 8.8 1.8 2 0 0 2 2 2 0 Transmembrane protein HSCB_C PF07743.8 EIW72007.1 - 1.4e-11 44.6 0.0 2.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EIW72007.1 - 1.4e-08 34.3 0.0 4.2e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain DZR PF12773.2 EIW72007.1 - 0.036 13.8 0.2 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.4 EIW72007.1 - 1.3 8.8 4.3 8.8 6.1 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 Tim17 PF02466.14 EIW72008.1 - 1.2e-34 119.0 4.4 1.4e-34 118.9 3.0 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cpn60_TCP1 PF00118.19 EIW72009.1 - 2.5e-146 488.0 0.1 2.9e-146 487.9 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PI3_PI4_kinase PF00454.22 EIW72010.1 - 1.8e-34 119.2 0.1 1.2e-33 116.5 0.0 2.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EIW72010.1 - 1.3e-22 79.8 0.0 3.7e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) RRM_1 PF00076.17 EIW72010.1 - 4.6e-15 54.9 0.0 1.1e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW72010.1 - 2.2e-13 49.9 0.0 7.9e-13 48.1 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW72010.1 - 1.7e-08 34.2 0.0 3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 EIW72011.1 - 8e-24 84.4 0.0 1.7e-14 54.2 0.0 3.1 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EIW72011.1 - 2.9e-09 37.3 2.7 0.0027 17.7 0.0 3.1 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EIW72011.1 - 0.0034 16.6 0.0 2 7.6 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIW72011.1 - 0.0054 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EIW72011.1 - 0.0092 16.3 6.5 0.22 11.8 0.2 2.8 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 EIW72011.1 - 0.066 12.8 0.8 0.25 10.9 0.3 2.2 1 1 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EIW72011.1 - 0.14 11.9 0.0 0.45 10.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 EIW72011.1 - 0.68 8.7 2.5 1.8 7.3 0.1 2.2 1 1 0 2 2 2 0 Type II/IV secretion system protein DUF667 PF05018.8 EIW72012.1 - 8.6e-10 38.1 0.0 9.8e-06 24.9 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF667) DUF4217 PF13959.1 EIW72012.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) Bud13 PF09736.4 EIW72014.1 - 0.096 12.9 0.8 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex NTR2 PF15458.1 EIW72016.1 - 0.11 11.7 4.2 0.15 11.2 2.9 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 DUF3848 PF12959.2 EIW72017.1 - 0.058 13.3 0.0 0.24 11.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3848) DUF3215 PF11503.3 EIW72018.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) DDE_1 PF03184.14 EIW72019.1 - 1.2e-31 109.5 0.0 2.6e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW72019.1 - 0.00012 21.8 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EIW72019.1 - 0.00015 21.5 0.7 0.0058 16.3 0.0 3.3 3 2 1 4 4 4 1 DDE superfamily endonuclease DUF1423 PF07227.6 EIW72019.1 - 0.083 11.5 11.1 0.12 10.9 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) CAF-1_p150 PF11600.3 EIW72019.1 - 0.5 9.7 29.1 0.85 8.9 20.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PcfK PF14058.1 EIW72019.1 - 0.52 10.4 10.2 0.94 9.6 7.1 1.4 1 0 0 1 1 1 0 PcfK-like protein Ycf1 PF05758.7 EIW72019.1 - 5 4.7 11.0 6.9 4.2 7.6 1.1 1 0 0 1 1 1 0 Ycf1 RNase_H2-Ydr279 PF09468.5 EIW72019.1 - 5.8 6.0 9.5 11 5.1 6.6 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3818 PF12825.2 EIW72019.1 - 7.2 5.1 5.9 11 4.6 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) PsbH PF00737.15 EIW72021.1 - 0.13 11.8 0.0 2.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Cullin PF00888.17 EIW72022.1 - 6.4e-140 467.4 0.0 9.3e-140 466.9 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EIW72022.1 - 5.7e-28 96.5 6.5 7e-28 96.2 0.2 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain RPAP3_C PF13877.1 EIW72022.1 - 0.058 13.3 0.0 0.35 10.8 0.0 2.4 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 PPR_3 PF13812.1 EIW72023.1 - 1.5e-05 24.9 0.0 0.019 15.1 0.0 3.6 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 EIW72023.1 - 0.015 15.1 0.0 0.13 12.2 0.0 2.6 3 0 0 3 3 3 0 PPR repeat TPR_16 PF13432.1 EIW72023.1 - 0.029 15.0 0.5 0.24 12.1 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_1 PF12854.2 EIW72023.1 - 0.045 13.2 0.0 0.3 10.6 0.0 2.4 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.1 EIW72023.1 - 0.073 13.0 0.0 3 7.8 0.0 3.3 3 1 0 3 3 3 0 PPR repeat family TPR_14 PF13428.1 EIW72023.1 - 0.087 13.5 0.4 4.9 8.0 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Rep_fac_C PF08542.6 EIW72023.1 - 0.099 12.6 0.0 3.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Replication factor C C-terminal domain zf-CCHC PF00098.18 EIW72024.1 - 0.0023 17.7 1.9 0.0042 16.9 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Med3 PF11593.3 EIW72026.1 - 0.052 12.7 2.0 0.05 12.8 1.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_transf_28 PF03033.15 EIW72027.1 - 5e-17 61.9 0.0 2e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EIW72027.1 - 5.5e-07 28.5 0.0 7.9e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EIW72027.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Ras PF00071.17 EIW72028.1 - 2.7e-46 156.9 0.0 3.1e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW72028.1 - 1.3e-14 54.7 0.0 1.9e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW72028.1 - 7.6e-08 31.7 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW72028.1 - 1.6e-05 24.4 0.0 5.3e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIW72028.1 - 0.0013 17.9 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EIW72028.1 - 0.0052 16.2 0.0 3.1 7.2 0.0 2.7 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EIW72028.1 - 0.057 13.5 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain GH114_assoc PF14741.1 EIW72028.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain DUF2875 PF11394.3 EIW72028.1 - 0.18 10.3 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) SIR2 PF02146.12 EIW72029.1 - 1.5e-53 181.1 0.0 1.8e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Avl9 PF09794.4 EIW72030.1 - 1.7e-124 415.1 0.0 2.2e-124 414.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EIW72030.1 - 5.1e-11 42.2 0.0 5.9e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EIW72030.1 - 9.5e-07 28.3 0.2 0.0016 17.7 1.3 3.1 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) TFIID_30kDa PF03540.8 EIW72030.1 - 0.097 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit DENN PF02141.16 EIW72030.1 - 0.54 9.9 2.2 3.7 7.2 0.2 2.9 3 1 1 4 4 4 0 DENN (AEX-3) domain UBN2_2 PF14227.1 EIW72032.1 - 1.8e-06 27.5 0.1 6.4e-06 25.7 0.0 2.0 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW72032.1 - 7.6e-06 25.7 0.0 2e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW72032.1 - 0.0064 16.0 3.1 0.14 11.6 0.1 2.3 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type Trypan_PARP PF05887.6 EIW72032.1 - 1.1 9.0 3.4 1.8 8.3 2.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3628 PF12300.3 EIW72032.1 - 7.9 6.4 10.7 0.77 9.7 4.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) Pam16 PF03656.8 EIW72035.1 - 8.4e-15 54.6 0.2 1.7e-08 34.3 0.0 2.0 2 0 0 2 2 2 2 Pam16 zf-C2H2 PF00096.21 EIW72036.1 - 9.5e-25 85.4 74.0 0.00012 22.2 0.5 10.6 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW72036.1 - 1.6e-17 62.4 75.2 0.0047 17.1 0.3 10.5 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW72036.1 - 1.4e-08 34.5 72.6 5.6e-05 23.2 0.3 11.8 13 0 0 13 13 13 5 Zinc-finger double domain Mut7-C PF01927.11 EIW72036.1 - 0.026 14.4 1.4 0.026 14.4 1.0 3.7 2 1 1 3 3 3 0 Mut7-C RNAse domain Pkinase PF00069.20 EIW72037.1 - 2.3e-12 46.6 0.0 4.5e-12 45.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72037.1 - 7.1e-05 22.0 0.0 0.00016 20.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW72037.1 - 0.039 13.6 0.8 0.039 13.6 0.6 1.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family PNRC PF15365.1 EIW72038.1 - 1.3 9.1 6.7 0.23 11.5 1.7 2.0 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator FMN_red PF03358.10 EIW72039.1 - 7e-20 71.0 0.0 9e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EIW72039.1 - 0.052 13.0 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold DHDPS PF00701.17 EIW72039.1 - 0.1 11.2 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Mad3_BUB1_I PF08311.7 EIW72040.1 - 2.4e-26 91.9 0.3 4.8e-26 91.0 0.2 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EIW72040.1 - 3e-14 52.7 0.0 4.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72040.1 - 7.7e-05 21.8 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RNF111_N PF15303.1 EIW72040.1 - 3.3 7.1 9.4 0.23 10.9 1.3 2.3 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus Macoilin PF09726.4 EIW72041.1 - 0.4 8.8 3.6 0.39 8.9 2.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 EIW72041.1 - 0.41 9.6 1.7 0.63 8.9 1.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter MFS_1 PF07690.11 EIW72043.1 - 7.9e-28 97.1 24.2 9.8e-28 96.8 16.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HpcH_HpaI PF03328.9 EIW72044.1 - 1e-36 125.9 1.8 1.2e-36 125.6 0.9 1.5 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Fungal_trans PF04082.13 EIW72045.1 - 1.4e-28 99.4 0.0 1.4e-27 96.2 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW72045.1 - 4.8e-09 35.9 10.3 8.4e-09 35.2 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1656 PF07869.7 EIW72045.1 - 0.091 12.5 0.7 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) 2-Hacid_dh_C PF02826.14 EIW72046.1 - 1.1e-45 154.9 0.0 1.8e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW72046.1 - 2.9e-16 59.1 0.0 3.5e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Cyclase PF04199.8 EIW72047.1 - 1.6e-16 60.4 0.0 2.2e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase MFS_1 PF07690.11 EIW72048.1 - 3.3e-34 118.1 30.6 3.8e-34 117.9 21.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Mem_trans PF03547.13 EIW72048.1 - 7 4.8 14.3 0.012 13.9 1.8 2.2 3 0 0 3 3 3 0 Membrane transport protein Raffinose_syn PF05691.7 EIW72049.1 - 8.8e-12 43.3 0.5 1.3e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Aldo_ket_red PF00248.16 EIW72050.1 - 4.9e-66 222.4 0.0 5.6e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UDG PF03167.14 EIW72050.1 - 0.056 12.9 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily YhfH PF14149.1 EIW72050.1 - 0.13 12.0 0.3 14 5.5 0.0 2.4 2 0 0 2 2 2 0 YhfH-like protein Toxin_11 PF07473.6 EIW72053.1 - 0.25 11.2 1.3 0.51 10.2 0.9 1.5 1 0 0 1 1 1 0 Spasmodic peptide gm9a DEAD PF00270.24 EIW72056.1 - 3.5e-49 166.5 0.0 5.6e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW72056.1 - 3.9e-27 93.9 0.0 1e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW72056.1 - 0.0024 17.7 0.0 0.014 15.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PAC2 PF09754.4 EIW72056.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 PAC2 family LigB PF02900.13 EIW72057.1 - 2.3e-41 141.5 0.0 2.8e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Resolvase PF00239.16 EIW72059.1 - 0.005 16.7 2.6 0.0098 15.7 1.8 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain zf-CCHC PF00098.18 EIW72059.1 - 0.031 14.2 4.3 0.062 13.2 3.0 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 EIW72059.1 - 0.055 12.9 0.2 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle UQ_con PF00179.21 EIW72062.1 - 1.1e-41 141.5 0.0 1.3e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW72062.1 - 3.5e-05 23.5 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Pkinase PF00069.20 EIW72063.1 - 1.6e-62 210.9 0.0 2.5e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72063.1 - 1.2e-40 139.1 0.0 2.7e-23 82.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW72063.1 - 5.1e-07 28.9 0.0 9.2e-06 24.8 0.0 2.5 2 1 0 2 2 2 1 Kinase-like DUF3552 PF12072.3 EIW72063.1 - 6.1e-06 25.5 7.3 1.3e-05 24.4 5.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) APH PF01636.18 EIW72063.1 - 0.016 14.9 0.1 0.47 10.1 0.0 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family GAGA_bind PF06217.7 EIW72063.1 - 0.045 13.7 1.2 0.1 12.5 0.8 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family Atg14 PF10186.4 EIW72063.1 - 0.077 11.9 4.8 0.14 11.0 3.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 EIW72063.1 - 3.8 5.8 10.2 0.7 8.2 3.6 1.8 2 0 0 2 2 2 0 AAA domain APG6 PF04111.7 EIW72063.1 - 6.4 5.7 14.3 0.9 8.5 6.8 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 FAD_binding_3 PF01494.14 EIW72064.1 - 5e-19 68.5 0.0 2.8e-16 59.5 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 EIW72064.1 - 9.5e-06 24.6 0.0 1.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 EIW72064.1 - 0.001 18.0 0.0 1.3 7.9 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein DUF4147 PF13660.1 EIW72064.1 - 0.12 11.4 0.0 0.39 9.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) VHS PF00790.14 EIW72065.1 - 1.4e-19 70.1 0.0 4.1e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EIW72065.1 - 6.2e-06 26.1 0.2 1.5e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 GAT domain CAF-1_p150 PF11600.3 EIW72065.1 - 7.7 5.8 37.6 0.25 10.6 3.5 2.8 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal IBR PF01485.16 EIW72066.1 - 8.6e-19 67.1 46.1 9.8e-11 41.3 2.3 4.8 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EIW72066.1 - 0.0001 22.0 6.6 0.0001 22.0 4.5 3.5 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 EIW72066.1 - 0.00023 21.1 7.2 0.00023 21.1 5.0 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW72066.1 - 0.00052 19.6 4.3 0.00052 19.6 3.0 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Nup84_Nup100 PF04121.8 EIW72067.1 - 2.3e-95 319.7 0.0 2.4e-94 316.4 0.0 1.9 2 0 0 2 2 2 1 Nuclear pore protein 84 / 107 TPR_19 PF14559.1 EIW72067.1 - 0.00018 21.7 1.4 0.0052 17.0 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW72067.1 - 0.48 11.2 6.1 13 6.7 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PAS_3 PF08447.6 EIW72068.1 - 0.0018 18.3 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 EIW72068.1 - 0.0029 17.4 10.0 0.0044 16.8 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EIW72069.1 - 1.4e-65 221.0 0.0 1.7e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72069.1 - 2.1e-28 99.1 0.0 3.1e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW72069.1 - 1e-05 24.6 0.0 1.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW72069.1 - 6.5e-05 22.0 0.3 0.00038 19.5 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Exo_endo_phos PF03372.18 EIW72070.1 - 3.6e-13 50.0 0.2 1.5e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIW72070.1 - 1.3e-12 47.3 0.0 3.2e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EIW72070.1 - 2.1e-06 27.5 1.2 6.1e-05 22.8 0.1 2.6 2 0 0 2 2 2 1 GRF zinc finger RNase_H2-Ydr279 PF09468.5 EIW72070.1 - 0.013 14.7 3.7 0.024 13.8 2.6 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF605 PF04652.11 EIW72070.1 - 0.77 9.0 24.0 1.1 8.5 16.6 1.3 1 0 0 1 1 1 0 Vta1 like Mitofilin PF09731.4 EIW72070.1 - 0.82 8.2 10.2 1.2 7.7 7.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CytochromB561_N PF09786.4 EIW72070.1 - 0.96 7.8 16.3 1.4 7.3 11.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Mgm101p PF06420.7 EIW72071.1 - 1.4e-90 301.1 0.0 1.8e-90 300.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 YEATS PF03366.11 EIW72072.1 - 1.3e-32 111.3 0.0 2.1e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 YEATS family FHA PF00498.21 EIW72073.1 - 1.6e-17 63.4 0.0 2.6e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain DUF4382 PF14321.1 EIW72073.1 - 0.028 14.5 0.0 0.063 13.3 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4382) SNARE PF05739.14 EIW72074.1 - 1.3e-07 31.2 1.2 1.3e-07 31.2 0.8 2.1 1 1 1 2 2 2 1 SNARE domain Gly_transf_sug PF04488.10 EIW72075.1 - 6.2e-07 29.7 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EIW72075.1 - 0.045 12.2 0.0 0.08 11.4 0.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Peptidase_M28 PF04389.12 EIW72076.1 - 2.2e-27 95.9 0.0 3.5e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIW72076.1 - 1.2e-06 28.2 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 GCV_T PF01571.16 EIW72077.1 - 1.9e-62 210.3 0.0 3.4e-62 209.5 0.0 1.4 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EIW72077.1 - 1.2e-20 73.3 0.3 3.7e-20 71.7 0.1 1.9 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EIW72077.1 - 0.015 15.1 0.3 0.92 9.3 0.0 2.6 2 1 1 3 3 3 0 Sarcosine oxidase, gamma subunit family TrmE_N PF10396.4 EIW72077.1 - 0.14 12.1 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus ThuA PF06283.6 EIW72078.1 - 2.4e-52 177.8 0.0 2.8e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Trehalose utilisation NAGLU_C PF12972.2 EIW72078.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain DUF4159 PF13709.1 EIW72078.1 - 0.034 13.2 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) SSP160 PF06933.6 EIW72078.1 - 0.94 7.3 12.1 1.3 6.9 8.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ATP-sulfurylase PF01747.12 EIW72080.1 - 3.3e-86 288.0 0.1 4.7e-86 287.5 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EIW72080.1 - 5.1e-49 165.7 0.0 7.6e-49 165.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 EIW72080.1 - 1.8e-47 160.9 0.0 2.8e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 EIW72080.1 - 0.00048 19.4 0.0 0.00072 18.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EIW72080.1 - 0.0017 18.2 0.1 0.004 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIW72080.1 - 0.042 14.1 0.0 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIW72080.1 - 0.12 13.1 0.2 0.62 10.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain SDA1 PF05285.7 EIW72081.1 - 2e-84 283.6 38.1 4.2e-84 282.5 19.4 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EIW72081.1 - 3.5e-20 72.0 0.1 1.1e-18 67.2 0.0 2.9 2 0 0 2 2 2 1 NUC130/3NT domain NIF PF03031.13 EIW72082.1 - 4.2e-52 176.0 0.1 4.8e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PEPCK_ATP PF01293.15 EIW72083.1 - 8.3e-216 716.9 0.0 1e-215 716.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 EIW72083.1 - 0.025 14.1 0.1 0.067 12.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EIW72083.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.13 EIW72084.1 - 7.3e-70 234.5 0.0 9.8e-70 234.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIW72084.1 - 2.1e-32 112.3 0.0 5.5e-32 111.0 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIW72084.1 - 2.9e-09 36.9 0.1 5.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW72084.1 - 0.00027 21.7 0.1 0.0012 19.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIW72084.1 - 0.0099 14.9 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin GBP PF02263.14 EIW72084.1 - 0.032 13.2 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain KTI12 PF08433.5 EIW72084.1 - 0.037 13.2 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Methyltransf_32 PF13679.1 EIW72084.1 - 0.093 12.4 0.6 0.37 10.4 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Ku PF02735.11 EIW72085.1 - 1.7e-27 96.1 0.2 1.4e-23 83.3 0.0 2.4 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EIW72085.1 - 1.9e-18 66.7 0.0 2.6e-16 59.7 0.0 2.5 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EIW72085.1 - 1.2e-06 28.9 0.6 1.7e-05 25.2 0.0 2.8 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EIW72085.1 - 2e-05 23.9 1.9 0.00058 19.3 0.7 2.6 2 0 0 2 2 2 1 SAP domain VWA_2 PF13519.1 EIW72085.1 - 7.9e-05 22.8 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Rho_N PF07498.7 EIW72085.1 - 0.003 17.2 3.0 0.0068 16.1 2.1 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Glyoxalase PF00903.20 EIW72086.1 - 5.8e-19 68.3 0.0 6.7e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EIW72086.1 - 3.8e-15 56.4 0.0 5.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EIW72086.1 - 1.4e-06 28.2 0.0 9.1e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EIW72086.1 - 0.0075 16.1 0.0 0.027 14.3 0.0 1.8 2 1 0 2 2 2 1 Glyoxalase-like domain Cation_efflux PF01545.16 EIW72087.1 - 5.2e-30 104.4 1.9 6.4e-30 104.2 1.3 1.1 1 0 0 1 1 1 1 Cation efflux family DUF59 PF01883.14 EIW72087.1 - 0.079 12.9 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF59 L31 PF09784.4 EIW72089.1 - 2.1e-40 136.9 0.4 2.4e-40 136.7 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 zf-RING_2 PF13639.1 EIW72090.1 - 3.7e-12 45.8 6.2 9.3e-12 44.5 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIW72090.1 - 3.6e-10 39.8 6.9 6.8e-10 38.9 4.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIW72090.1 - 8.4e-09 34.9 3.7 8.4e-09 34.9 2.6 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW72090.1 - 4.4e-08 33.0 5.9 3e-07 30.3 4.1 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW72090.1 - 2.7e-07 30.1 3.2 5.2e-07 29.2 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW72090.1 - 1.6e-06 27.7 4.9 4e-06 26.4 3.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EIW72090.1 - 3.8e-06 26.6 6.3 7.6e-06 25.6 4.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EIW72090.1 - 0.0056 16.6 4.5 0.02 14.9 3.1 2.0 1 1 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 EIW72090.1 - 0.01 15.5 5.0 0.015 15.0 1.3 2.7 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EIW72090.1 - 0.015 14.8 0.4 0.044 13.3 0.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.6 EIW72090.1 - 0.085 12.8 5.2 0.23 11.4 3.6 1.8 1 1 0 1 1 1 0 RING-like domain Baculo_RING PF05883.6 EIW72090.1 - 0.089 12.6 0.8 0.16 11.8 0.6 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 EIW72090.1 - 0.34 10.9 7.5 5.9 6.9 5.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EIW72090.1 - 7.3 6.5 10.8 0.054 13.3 1.1 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TRP PF06011.7 EIW72091.1 - 1.1e-82 278.0 19.0 1.4e-82 277.6 13.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EIW72091.1 - 9.5e-27 93.7 0.1 1.6e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 ML-like domain DUF912 PF06024.7 EIW72091.1 - 0.01 15.8 0.1 1.5 8.8 0.0 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) KH_1 PF00013.24 EIW72092.1 - 1.4e-71 235.9 44.9 7.5e-14 51.1 1.0 13.4 13 1 0 13 13 13 10 KH domain KH_3 PF13014.1 EIW72092.1 - 1.2e-55 184.3 27.6 1.4e-08 34.1 0.1 13.6 14 0 0 14 14 14 10 KH domain SLS PF14611.1 EIW72092.1 - 4.3e-06 26.3 9.2 0.057 12.8 0.0 7.1 5 2 3 8 8 8 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EIW72092.1 - 6.4e-06 25.6 30.5 0.61 9.6 0.0 8.6 8 1 1 9 9 9 4 KH domain KH_4 PF13083.1 EIW72092.1 - 0.00039 19.9 11.2 1.1 8.9 0.0 6.5 7 0 0 7 7 7 2 KH domain Aldo_ket_red PF00248.16 EIW72092.1 - 0.028 13.2 0.1 1.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Aldo/keto reductase family BMC PF00936.14 EIW72092.1 - 0.72 9.5 12.9 1.8 8.3 0.2 5.5 6 0 0 6 6 6 0 BMC domain Solute_trans_a PF03619.11 EIW72093.1 - 2.6e-46 158.1 18.7 4e-46 157.5 13.0 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Solute_trans_a PF03619.11 EIW72094.1 - 6.4e-34 117.5 14.0 4.4e-33 114.7 9.7 1.9 1 1 0 1 1 1 1 Organic solute transporter Ostalpha BT1 PF03092.11 EIW72094.1 - 0.0016 17.2 1.7 0.0021 16.8 1.2 1.3 1 0 0 1 1 1 1 BT1 family Ribosomal_S11 PF00411.14 EIW72096.1 - 0.0029 17.7 0.3 0.093 12.9 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S11 ORC6 PF05460.8 EIW72096.1 - 0.52 9.3 11.6 0.76 8.8 8.0 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF605 PF04652.11 EIW72096.1 - 2.2 7.5 21.5 2.7 7.3 14.9 1.1 1 0 0 1 1 1 0 Vta1 like Malic_M PF03949.10 EIW72097.1 - 1.3e-75 254.2 0.0 2e-75 253.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIW72097.1 - 1.6e-59 200.5 0.0 2.4e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Pyr_redox_2 PF07992.9 EIW72097.1 - 0.029 14.2 0.0 0.097 12.5 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SNARE_assoc PF09335.6 EIW72098.1 - 5.4e-11 42.7 7.3 5.4e-11 42.7 5.1 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2910 PF11139.3 EIW72098.1 - 6.8e-06 25.3 0.7 1.9e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2910) BTB PF00651.26 EIW72099.1 - 2.7e-14 53.0 0.0 1.2e-08 34.8 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain DUF3804 PF12707.2 EIW72099.1 - 0.025 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) Secretin_N_2 PF07655.8 EIW72100.1 - 1.2 9.5 9.9 0.074 13.4 2.5 2.1 2 1 0 2 2 2 0 Secretin N-terminal domain zf-CCHC PF00098.18 EIW72102.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW72102.1 - 0.26 11.5 9.2 0.069 13.3 4.2 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW72102.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW72103.1 - 0.026 13.9 0.1 0.073 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Dysbindin PF04440.11 EIW72103.1 - 0.08 12.6 4.8 0.25 11.0 3.3 1.8 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) PhyH PF05721.8 EIW72106.1 - 8.6e-50 169.6 0.0 1e-49 169.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EIW72106.1 - 0.04 14.2 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 EIW72106.1 - 0.066 13.7 0.0 0.14 12.6 0.0 1.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SPA PF08616.5 EIW72107.1 - 4.1e-09 36.1 0.0 6.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.16 EIW72107.1 - 0.0098 15.6 0.7 0.029 14.0 0.1 2.2 2 1 0 2 2 2 1 DENN (AEX-3) domain DUF2981 PF11200.3 EIW72107.1 - 0.038 13.0 0.4 0.061 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Avl9 PF09794.4 EIW72107.1 - 0.25 9.8 0.0 1.3 7.4 0.0 2.0 3 0 0 3 3 3 0 Transport protein Avl9 EXS PF03124.9 EIW72108.1 - 4.5e-82 275.8 23.1 5.6e-82 275.5 16.0 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EIW72108.1 - 9.1e-40 137.1 0.0 3.7e-39 135.1 0.0 1.9 1 1 0 1 1 1 1 SPX domain DUF3452 PF11934.3 EIW72108.1 - 0.0027 17.0 0.7 0.006 15.9 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) DNA_ligase_A_M PF01068.16 EIW72109.1 - 1.1e-63 214.2 0.2 2e-63 213.4 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIW72109.1 - 5.6e-56 189.1 0.5 9.4e-56 188.4 0.4 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EIW72109.1 - 1.6e-24 86.1 0.0 3.4e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EIW72109.1 - 0.093 12.4 0.2 14 5.4 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain zf-RanBP PF00641.13 EIW72110.1 - 1.1e-09 37.2 11.2 4.5e-05 22.4 1.6 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 EIW72110.1 - 0.0073 15.8 4.5 1.3 8.6 0.0 2.9 3 0 0 3 3 3 2 Sec23/Sec24 zinc finger Prok-RING_2 PF14445.1 EIW72110.1 - 0.3 11.0 2.2 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 PHD_2 PF13831.1 EIW72110.1 - 0.7 9.2 2.3 11 5.4 0.1 2.4 2 0 0 2 2 2 0 PHD-finger zf-P11 PF03854.9 EIW72110.1 - 1.2 8.6 8.0 1.8 8.0 0.4 2.5 2 0 0 2 2 2 0 P-11 zinc finger RCC1 PF00415.13 EIW72111.1 - 4.8e-30 103.5 9.1 8.3e-07 29.1 0.1 6.1 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIW72111.1 - 5.6e-17 60.8 7.4 6.7e-05 22.3 0.0 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 EIW72111.1 - 1.6e-10 40.4 6.7 3e-10 39.6 4.6 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EIW72111.1 - 0.0008 19.0 2.8 0.0023 17.6 1.9 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.17 EIW72111.1 - 0.043 13.5 0.6 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EIW72111.1 - 0.08 12.2 0.8 0.21 10.9 0.5 1.7 1 0 0 1 1 1 0 PHD-finger NAD_kinase PF01513.16 EIW72112.1 - 6.4e-67 225.3 0.0 1.3e-66 224.2 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase Sporozoite_P67 PF05642.6 EIW72112.1 - 0.047 11.5 4.3 0.08 10.8 3.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleo_P87 PF07267.6 EIW72112.1 - 0.29 9.7 5.3 0.43 9.1 3.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.7 EIW72112.1 - 2.6 7.2 5.6 5.5 6.1 3.9 1.5 1 0 0 1 1 1 0 NOA36 protein VID27 PF08553.5 EIW72112.1 - 3.3 5.8 5.7 4.7 5.3 3.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Telomere_reg-2 PF10193.4 EIW72113.1 - 1.5e-27 96.1 0.1 6.4e-27 94.0 0.0 2.2 3 0 0 3 3 3 1 Telomere length regulation protein Asp PF00026.18 EIW72117.1 - 1e-75 254.9 8.2 1.1e-75 254.7 5.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW72117.1 - 1.2e-06 28.5 6.7 2.4e-05 24.3 3.0 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Bax1-I PF01027.15 EIW72118.1 - 5.8e-52 176.2 22.5 6.8e-52 176.0 15.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Amastin PF07344.6 EIW72118.1 - 0.13 11.8 2.4 0.44 10.1 1.7 2.1 1 1 0 1 1 1 0 Amastin surface glycoprotein Tet_JBP PF12851.2 EIW72122.1 - 1.2e-08 34.4 0.0 2.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EIW72122.1 - 3.8e-06 27.3 0.0 1.2e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tannase PF07519.6 EIW72122.1 - 0.029 13.0 0.2 0.041 12.6 0.1 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase TnpV PF14198.1 EIW72122.1 - 0.071 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpV PBP PF01161.15 EIW72124.1 - 1.3e-15 57.5 0.1 2.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4187 PF13821.1 EIW72125.1 - 2.3e-14 52.7 0.6 5.2e-14 51.5 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EIW72125.1 - 2.9e-05 23.7 4.1 3.5e-05 23.4 1.1 2.3 2 0 0 2 2 2 1 G-patch domain Use1 PF09753.4 EIW72125.1 - 0.27 10.6 2.3 1.2 8.4 0.0 2.4 2 1 0 3 3 3 0 Membrane fusion protein Use1 MRP-S26 PF14943.1 EIW72126.1 - 0.015 14.8 3.6 0.021 14.3 2.5 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 IFT57 PF10498.4 EIW72126.1 - 0.07 11.8 2.0 0.12 11.1 1.4 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 V_ATPase_I PF01496.14 EIW72126.1 - 0.31 8.8 1.8 0.44 8.3 1.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EIW72126.1 - 0.79 9.2 4.5 1.6 8.2 3.2 1.3 1 1 0 1 1 1 0 IncA protein Med21 PF11221.3 EIW72126.1 - 4.2 7.3 6.5 0.29 11.1 0.8 1.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex TFIID_20kDa PF03847.8 EIW72127.1 - 8.1e-11 42.0 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EIW72127.1 - 0.051 13.6 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone A_deamin PF02137.13 EIW72128.1 - 6e-74 249.4 0.0 7.8e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain SCA7 PF08313.7 EIW72129.1 - 1.7e-25 88.4 0.0 1.9e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain Tachystatin_A PF11406.3 EIW72129.1 - 0.012 15.4 0.1 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A GPI-anchored PF10342.4 EIW72130.1 - 3.4e-06 27.4 5.5 3.4e-06 27.4 3.8 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIA PF03153.8 EIW72130.1 - 0.13 12.0 1.5 0.17 11.7 1.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S8e PF01201.17 EIW72131.1 - 4.1e-49 166.1 0.5 4.8e-49 165.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e G_glu_transpept PF01019.16 EIW72132.1 - 1.3e-136 456.0 0.0 1.5e-136 455.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Med13_C PF06333.7 EIW72133.1 - 2.4e-07 29.6 0.0 5.7e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Alpha-amylase PF00128.19 EIW72134.1 - 3.6e-24 85.7 0.5 7.5e-21 74.8 0.2 3.4 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EIW72134.1 - 5.9e-18 65.2 0.1 9.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EIW72134.1 - 4.8e-08 32.5 0.0 9.8e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIW72134.1 - 6.3e-07 29.6 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 RRM_1 PF00076.17 EIW72135.1 - 9.1e-10 38.0 0.0 1.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW72135.1 - 3e-09 36.7 0.0 4.6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EIW72135.1 - 1.2e-06 28.8 0.7 1.2e-06 28.8 0.5 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EIW72135.1 - 4.4e-06 26.4 0.0 6.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC4_C PF14629.1 EIW72136.1 - 1.1e-22 80.4 0.0 1.6e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EIW72136.1 - 6.7e-18 65.3 0.4 3.7e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW72136.1 - 0.00019 21.5 0.0 0.00054 20.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EIW72136.1 - 0.0026 17.9 0.1 0.031 14.4 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EIW72136.1 - 0.0061 16.2 0.1 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 EIW72136.1 - 0.06 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EIW72136.1 - 0.088 12.5 0.8 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain Pribosyltran PF00156.22 EIW72137.1 - 4.8e-11 42.4 0.0 7.8e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 EIW72137.1 - 0.0034 16.7 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase PEPcase_2 PF14010.1 EIW72137.1 - 0.084 11.1 0.1 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Ribosom_S12_S23 PF00164.20 EIW72138.1 - 7e-39 132.0 0.4 8.1e-39 131.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Amino_oxidase PF01593.19 EIW72139.1 - 7.3e-19 68.1 0.0 4.4e-10 39.2 0.0 2.8 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIW72139.1 - 4.5e-10 39.4 0.0 8.7e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW72139.1 - 2.2e-07 30.1 0.0 8.6e-05 21.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW72139.1 - 0.00057 20.2 0.0 0.15 12.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW72139.1 - 0.0053 16.6 0.0 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIW72139.1 - 0.0061 15.2 0.0 0.0086 14.7 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EIW72139.1 - 0.04 12.7 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EIW72139.1 - 0.055 12.5 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EIW72139.1 - 0.099 12.6 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW72139.1 - 0.12 10.8 0.0 0.36 9.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Mqo PF06039.10 EIW72139.1 - 0.17 10.0 0.0 1.8 6.6 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) SET PF00856.23 EIW72140.1 - 4.2e-23 82.4 0.1 4.2e-23 82.4 0.1 3.0 2 2 0 2 2 2 1 SET domain SRI PF08236.6 EIW72140.1 - 4.7e-17 61.7 10.9 4.7e-17 61.7 7.6 2.6 3 0 0 3 3 3 1 SRI (Set2 Rpb1 interacting) domain SelP_N PF04592.9 EIW72140.1 - 0.054 12.8 13.9 0.15 11.3 9.7 1.9 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EIW72140.1 - 1.5 7.7 9.1 2.9 6.7 6.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DIL PF01843.14 EIW72141.1 - 1.6e-27 95.4 0.7 3.7e-27 94.2 0.5 1.7 1 0 0 1 1 1 1 DIL domain Ank_5 PF13857.1 EIW72141.1 - 5.2e-05 23.3 0.0 0.00017 21.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EIW72141.1 - 0.00016 21.3 0.1 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EIW72141.1 - 0.0078 16.5 0.0 0.05 13.9 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIW72141.1 - 0.017 15.2 2.3 0.67 10.3 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.1 EIW72141.1 - 0.035 14.6 0.1 62 4.2 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) UCH PF00443.24 EIW72145.1 - 1.2e-77 260.6 0.0 2.3e-77 259.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW72145.1 - 1.1e-21 77.5 0.0 2.3e-13 50.2 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EIW72145.1 - 1.4e-06 28.6 0.0 4e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 DUSP domain PhnA_Zn_Ribbon PF08274.7 EIW72145.1 - 0.072 12.8 2.4 5.1 6.9 0.3 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon CpXC PF14353.1 EIW72145.1 - 0.16 11.9 0.4 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.5 EIW72145.1 - 0.23 11.4 2.6 11 6.0 0.3 2.7 2 0 0 2 2 2 0 Zinc ribbon domain MFS_1 PF07690.11 EIW72146.1 - 4.2e-23 81.6 28.7 8.6e-19 67.4 11.8 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily ATG22 PF11700.3 EIW72146.1 - 0.59 8.5 17.4 0.0061 15.0 3.3 2.6 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like PPP4R2 PF09184.6 EIW72146.1 - 2.2 7.7 15.8 4.7 6.6 11.0 1.5 1 0 0 1 1 1 0 PPP4R2 Zn_clus PF00172.13 EIW72147.1 - 3.1e-08 33.3 8.5 4.7e-08 32.8 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EIW72150.1 - 1.3e-31 107.3 7.7 1e-07 31.5 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EIW72150.1 - 4.7e-06 26.4 0.2 0.00034 20.3 0.1 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF605 PF04652.11 EIW72150.1 - 6.4 6.0 15.9 9.3 5.5 11.0 1.1 1 0 0 1 1 1 0 Vta1 like Exo_endo_phos PF03372.18 EIW72152.1 - 3.6e-18 66.4 0.3 5.2e-18 65.8 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EIW72152.1 - 4.5e-13 48.4 4.3 1.7e-06 27.4 0.4 2.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW72152.1 - 3.3e-08 33.1 5.9 4.1e-07 29.6 0.7 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EIW72152.1 - 4e-06 26.1 4.3 2.2 8.6 0.0 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EIW72152.1 - 0.0099 15.9 8.1 5.2 7.7 0.5 5.0 5 0 0 5 5 5 2 Leucine rich repeat DUF605 PF04652.11 EIW72153.1 - 0.0053 16.1 2.8 0.0053 16.1 1.9 2.2 2 0 0 2 2 2 1 Vta1 like LRR_4 PF12799.2 EIW72154.1 - 3.5e-54 179.6 54.6 6.4e-09 35.2 4.0 13.8 7 3 8 15 15 15 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW72154.1 - 2.1e-52 174.7 89.4 1.4e-14 53.5 2.7 9.7 5 3 7 13 13 13 12 Leucine rich repeat PP2C PF00481.16 EIW72154.1 - 1.1e-36 126.5 0.0 3.1e-36 125.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 EIW72154.1 - 5.5e-31 101.8 53.1 0.0021 17.8 0.1 19.5 19 1 1 20 20 20 11 Leucine Rich Repeat Guanylate_cyc PF00211.15 EIW72154.1 - 7.2e-26 90.6 0.0 1.3e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_7 PF13504.1 EIW72154.1 - 3.3e-14 50.5 52.0 0.033 14.3 0.1 18.3 20 0 0 20 20 20 4 Leucine rich repeat LRR_6 PF13516.1 EIW72154.1 - 8.7e-07 28.3 61.3 4 7.7 0.1 16.9 17 3 1 18 18 18 5 Leucine Rich repeat LRR_5 PF13306.1 EIW72154.1 - 8.8e-07 28.6 1.0 0.083 12.5 0.0 3.9 3 1 0 3 3 3 2 Leucine rich repeats (6 copies) PP2C_2 PF13672.1 EIW72154.1 - 0.26 10.6 0.0 0.52 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C Mg_trans_NIPA PF05653.9 EIW72155.1 - 1.8e-64 217.5 11.9 2.1e-64 217.3 8.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EIW72155.1 - 2.2e-07 30.9 10.2 2.2e-07 30.9 7.0 2.9 3 0 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EIW72155.1 - 5.4e-05 23.3 10.8 5.4e-05 23.3 7.5 2.7 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EIW72155.1 - 0.0025 16.9 1.4 0.0048 16.0 1.0 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter P5-ATPase PF12409.3 EIW72155.1 - 0.12 12.2 1.4 0.28 11.0 0.6 2.0 1 1 1 2 2 2 0 P5-type ATPase cation transporter DUF2937 PF11157.3 EIW72155.1 - 0.2 10.9 1.4 0.43 9.8 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) TPT PF03151.11 EIW72155.1 - 4 7.0 16.3 0.1 12.2 5.9 2.3 2 2 1 3 3 3 0 Triose-phosphate Transporter family PIRT PF15099.1 EIW72155.1 - 7.6 5.7 6.8 12 5.1 1.1 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Saccharop_dh PF03435.13 EIW72157.1 - 4.4e-22 78.5 0.0 6.2e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EIW72157.1 - 5.4e-06 26.5 0.0 8.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EIW72157.1 - 0.02 15.2 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Bestrophin PF01062.16 EIW72158.1 - 1.4e-45 155.5 4.1 2.1e-29 102.3 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel GFO_IDH_MocA PF01408.17 EIW72159.1 - 4.8e-31 107.7 0.5 8.4e-31 106.9 0.4 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EIW72159.1 - 0.0017 18.7 0.2 0.0029 17.9 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Phage_GP20 PF06810.6 EIW72160.1 - 0.001 18.5 10.2 0.001 18.5 7.0 5.0 3 2 1 5 5 5 1 Phage minor structural protein GP20 V_ATPase_I PF01496.14 EIW72160.1 - 8 4.1 27.4 0.14 10.0 3.3 2.5 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 EIW72161.1 - 1.4e-51 170.5 30.2 2.1e-11 43.2 0.1 12.3 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 EIW72161.1 - 1.4e-18 66.7 0.0 4.1e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family PD40 PF07676.7 EIW72161.1 - 0.0049 16.4 0.3 14 5.4 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 EIW72161.1 - 0.01 15.5 0.0 2.7 7.6 0.0 3.3 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term DUF1513 PF07433.6 EIW72161.1 - 0.029 13.2 0.1 6.5 5.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 EIW72161.1 - 0.031 12.5 0.2 2.1 6.5 0.0 3.4 4 1 0 4 4 4 0 Cytochrome D1 heme domain LRR_8 PF13855.1 EIW72162.1 - 1.3e-11 44.0 15.5 3.3e-06 26.7 2.0 3.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EIW72162.1 - 2e-08 33.6 22.6 1.8e-05 24.2 2.1 5.0 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIW72162.1 - 5.2e-05 22.7 10.7 0.38 10.9 0.1 6.9 6 1 0 6 6 6 1 Leucine Rich Repeat LRRNT_2 PF08263.7 EIW72162.1 - 0.00044 20.1 0.6 0.0022 17.9 0.4 2.3 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Zn_peptidase PF04228.8 EIW72162.1 - 0.022 13.9 0.1 0.037 13.2 0.1 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase LRR_6 PF13516.1 EIW72162.1 - 0.051 13.6 7.5 0.62 10.3 0.2 4.8 4 1 1 5 5 5 0 Leucine Rich repeat STT3 PF02516.9 EIW72164.1 - 4.4e-125 418.3 42.6 1.6e-123 413.2 29.5 2.1 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF1811 PF08838.5 EIW72166.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) DEAD PF00270.24 EIW72168.1 - 1.1e-33 116.1 0.0 2e-31 108.7 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW72168.1 - 2.2e-26 91.4 0.2 4.2e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EIW72168.1 - 0.00024 21.0 0.2 0.0011 18.9 0.0 2.1 3 0 0 3 3 3 1 Helicase C-terminal domain AAA_22 PF13401.1 EIW72168.1 - 0.015 15.4 0.1 0.087 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1253 PF06862.7 EIW72168.1 - 0.082 11.2 0.0 0.8 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DUF1811 PF08838.5 EIW72168.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) tRNA-synt_1b PF00579.20 EIW72168.1 - 0.13 11.3 0.2 0.48 9.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Arf PF00025.16 EIW72169.1 - 7.3e-78 259.7 0.0 8.2e-78 259.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIW72169.1 - 2.3e-13 49.8 0.0 2.5e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EIW72169.1 - 1.2e-11 44.2 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIW72169.1 - 6.2e-11 41.6 0.9 8e-07 28.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EIW72169.1 - 6.6e-10 38.5 0.0 7.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIW72169.1 - 9.9e-08 32.5 0.0 1.3e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW72169.1 - 8.5e-05 22.4 0.0 0.00022 21.1 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EIW72169.1 - 0.0019 17.3 0.1 0.003 16.6 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase R3H PF01424.17 EIW72170.1 - 0.0026 17.4 0.0 0.0065 16.1 0.0 1.6 1 0 0 1 1 1 1 R3H domain DUF2015 PF09435.5 EIW72171.1 - 1.3e-33 115.4 0.0 1.5e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) ESX-1_EspG PF14011.1 EIW72171.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 EspG family TRAUB PF08164.7 EIW72172.1 - 3.7e-22 78.2 0.2 1.4e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EIW72172.1 - 2.9e-16 59.8 0.0 2.9e-16 59.8 0.0 2.7 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor CDC45 PF02724.9 EIW72172.1 - 0.00032 18.8 19.6 0.00032 18.8 13.6 1.6 2 0 0 2 2 2 1 CDC45-like protein Daxx PF03344.10 EIW72172.1 - 0.0038 15.8 25.6 0.0071 14.8 17.8 1.5 1 0 0 1 1 1 1 Daxx Family SDA1 PF05285.7 EIW72172.1 - 0.0059 15.9 30.1 0.0059 15.9 20.9 1.8 2 0 0 2 2 2 1 SDA1 Nop14 PF04147.7 EIW72172.1 - 0.0068 14.3 40.4 0.011 13.7 28.0 1.2 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.10 EIW72172.1 - 0.21 10.1 8.0 0.27 9.8 5.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CENP-T PF15511.1 EIW72172.1 - 0.75 8.9 25.2 1.3 8.1 17.5 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T eIF-3c_N PF05470.7 EIW72172.1 - 1.9 6.4 12.6 2.8 5.9 8.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.5 EIW72172.1 - 2.5 7.0 34.0 0.11 11.5 19.4 1.7 2 0 0 2 2 2 0 BUD22 Mpp10 PF04006.7 EIW72172.1 - 3.8 5.7 34.5 6.3 5.0 23.9 1.4 1 0 0 1 1 1 0 Mpp10 protein Sec63 PF02889.11 EIW72173.1 - 1.3e-77 261.1 0.1 2e-77 260.5 0.1 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EIW72173.1 - 3.2e-43 147.1 0.7 6.6e-27 94.0 0.1 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EIW72173.1 - 6.4e-13 48.9 0.0 1.2e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIW72173.1 - 8.8e-08 31.9 0.0 2.6e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IstB_IS21 PF01695.12 EIW72173.1 - 1.1e-05 24.8 0.0 0.21 10.9 0.0 3.4 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_19 PF13245.1 EIW72173.1 - 1.5e-05 24.6 0.0 0.012 15.3 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 EIW72173.1 - 0.00077 19.6 0.1 0.14 12.2 0.1 3.3 2 1 0 2 2 2 1 AAA domain PhoH PF02562.11 EIW72173.1 - 0.00091 18.5 0.0 1.1 8.4 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_10 PF12846.2 EIW72173.1 - 0.0029 17.0 0.0 0.5 9.7 0.0 3.6 4 0 0 4 4 4 1 AAA-like domain SNF2_N PF00176.18 EIW72173.1 - 0.026 13.3 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain UvrD-helicase PF00580.16 EIW72173.1 - 0.043 13.0 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ThylakoidFormat PF11264.3 EIW72173.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Thylakoid formation protein SCP2 PF02036.12 EIW72174.1 - 5.4e-27 94.0 1.4 6.6e-27 93.7 1.0 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EIW72174.1 - 0.0001 22.2 0.4 0.00015 21.7 0.3 1.5 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Frataxin_Cyay PF01491.11 EIW72174.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Frataxin-like domain PAP1 PF08601.5 EIW72175.1 - 1.4 8.4 7.6 0.78 9.3 4.1 1.4 1 1 0 1 1 1 0 Transcription factor PAP1 Tubulin PF00091.20 EIW72177.1 - 7e-71 238.4 0.0 1.2e-70 237.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIW72177.1 - 5.1e-39 133.1 0.1 8.4e-39 132.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIW72177.1 - 2.9e-06 27.3 0.0 6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EIW72177.1 - 0.0098 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain GlnD_UR_UTase PF08335.6 EIW72177.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase Glyco_hydro_88 PF07470.8 EIW72178.1 - 2.9e-14 52.8 1.6 2.9e-14 52.8 1.1 1.4 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 SUR7 PF06687.7 EIW72179.1 - 3.5e-14 52.8 16.2 6.3e-14 52.0 11.2 1.4 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EIW72179.1 - 0.17 11.5 23.6 0.46 10.1 14.7 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2422 PF10337.4 EIW72179.1 - 1 8.0 5.1 1.7 7.3 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF3487 PF11990.3 EIW72179.1 - 4.4 6.7 14.8 0.51 9.7 2.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) Lysis_S PF04971.7 EIW72179.1 - 6.7 6.4 6.4 9.6 5.9 1.3 3.0 2 1 0 2 2 2 0 Lysis protein S DUF2884 PF11101.3 EIW72180.1 - 0.053 12.9 0.9 0.15 11.3 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Apolipoprotein PF01442.13 EIW72180.1 - 0.9 9.0 5.0 5.8 6.3 3.5 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Vps55 PF04133.9 EIW72181.1 - 2.4e-43 146.6 1.4 2.7e-43 146.5 1.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF1469 PF07332.6 EIW72181.1 - 0.52 10.0 12.1 2.8 7.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DAHP_synth_1 PF00793.15 EIW72182.1 - 4.4e-90 301.0 0.0 5.6e-90 300.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Asp PF00026.18 EIW72183.1 - 1.5e-35 122.9 0.0 4.2e-20 72.2 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic aspartyl protease DUF4112 PF13430.1 EIW72184.1 - 1.2e-26 92.6 0.2 1.7e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) PTH2 PF01981.11 EIW72185.1 - 1.5e-43 147.1 0.0 1.9e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Cwf_Cwc_15 PF04889.7 EIW72185.1 - 0.096 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Acetyltransf_1 PF00583.19 EIW72186.1 - 3.3e-12 46.2 0.0 2.4e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW72186.1 - 3.8e-07 30.1 0.0 9.3e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW72186.1 - 0.00018 21.2 0.1 0.00093 18.9 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EIW72186.1 - 0.0032 17.5 0.0 0.4 10.8 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Myb_DNA-bind_3 PF12776.2 EIW72187.1 - 9.6e-13 48.5 0.7 1.8e-12 47.6 0.5 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EIW72187.1 - 3.3e-08 33.5 0.3 6.5e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EIW72187.1 - 0.00021 21.1 0.1 0.00056 19.7 0.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW72187.1 - 0.019 15.0 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF605 PF04652.11 EIW72187.1 - 1.4 8.2 19.1 1.7 7.9 13.2 1.2 1 0 0 1 1 1 0 Vta1 like RVT_2 PF07727.9 EIW72190.1 - 4.9e-78 261.4 0.0 7.4e-78 260.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SET PF00856.23 EIW72193.1 - 2.8e-10 40.7 0.0 1e-08 35.6 0.0 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EIW72193.1 - 5.6e-06 26.1 4.7 5.6e-06 26.1 3.2 2.6 2 1 0 2 2 2 1 MYND finger Glycos_transf_1 PF00534.15 EIW72195.1 - 1.3e-12 47.4 0.0 2.9e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIW72195.1 - 0.0013 18.8 0.1 0.015 15.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Rhomboid PF01694.17 EIW72196.1 - 1.6e-12 47.6 14.3 6.7e-12 45.6 9.9 2.0 1 1 0 1 1 1 1 Rhomboid family TPR_11 PF13414.1 EIW72197.1 - 5.9e-20 70.6 10.2 2.6e-11 42.9 0.2 3.8 2 2 3 5 5 5 3 TPR repeat TPR_1 PF00515.23 EIW72197.1 - 4.4e-18 64.0 8.8 5.8e-05 22.5 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIW72197.1 - 4.2e-16 57.7 9.0 0.0045 17.0 0.0 5.9 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIW72197.1 - 2.4e-13 49.4 5.8 0.011 16.3 0.0 6.4 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIW72197.1 - 9.1e-13 47.0 12.5 0.00056 19.6 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIW72197.1 - 5.1e-11 42.3 7.1 5.9e-06 26.1 0.1 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIW72197.1 - 1e-09 38.5 7.6 0.00028 21.1 1.1 4.7 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW72197.1 - 2.3e-09 37.6 6.0 6.9e-05 23.4 0.1 4.6 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW72197.1 - 3.9e-07 29.3 2.5 0.37 10.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW72197.1 - 2.2e-06 27.0 6.9 0.4 10.5 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 EIW72197.1 - 4.2e-05 23.5 8.0 0.00058 19.9 0.4 4.3 2 1 3 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EIW72197.1 - 0.00049 20.1 5.2 0.0042 17.2 0.4 3.0 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIW72197.1 - 0.00084 19.6 4.2 13 6.4 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIW72197.1 - 0.044 13.7 4.0 5.3 7.1 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIW72197.1 - 0.048 13.5 0.8 7.5 6.4 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EIW72197.1 - 0.054 13.2 2.2 7.2 6.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PMSR PF01625.16 EIW72200.1 - 3.6e-53 179.6 1.9 4.3e-53 179.3 1.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PEMT PF04191.8 EIW72203.1 - 1.7e-52 175.9 11.2 7.9e-33 112.7 0.6 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase Cullin PF00888.17 EIW72204.1 - 2.2e-68 231.2 4.4 2.9e-68 230.8 0.1 2.0 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 EIW72204.1 - 1.4e-18 66.4 2.5 4.2e-18 64.9 1.7 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain SMC_N PF02463.14 EIW72205.1 - 3.8e-64 215.9 4.0 2.1e-63 213.5 2.7 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIW72205.1 - 4.4e-20 71.8 7.6 7.2e-20 71.1 0.2 4.0 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EIW72205.1 - 1.2e-13 51.6 6.0 4.9e-06 26.7 0.2 3.7 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EIW72205.1 - 3e-10 40.7 30.7 3e-10 40.7 21.3 6.1 2 2 0 2 2 1 1 AAA domain AAA_29 PF13555.1 EIW72205.1 - 1.6e-05 24.3 0.1 5.3e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EIW72205.1 - 0.00077 18.6 4.3 0.00077 18.6 3.0 3.3 3 2 0 3 3 2 1 AAA ATPase domain MscS_porin PF12795.2 EIW72205.1 - 0.00094 18.5 31.1 0.00094 18.5 21.5 6.1 3 3 2 6 6 6 2 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EIW72205.1 - 0.011 14.9 22.9 0.078 12.1 1.9 4.8 3 2 2 5 5 5 0 Reovirus sigma C capsid protein gpW PF02831.10 EIW72205.1 - 0.058 12.9 1.5 1.4 8.5 0.1 3.5 2 0 0 2 2 2 0 gpW ABC_tran PF00005.22 EIW72205.1 - 0.11 12.8 18.0 0.47 10.7 0.0 5.4 3 2 0 3 3 3 0 ABC transporter YojJ PF10372.4 EIW72205.1 - 6.1 6.7 8.1 1.5 8.7 1.2 3.5 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus zf-UBP PF02148.14 EIW72206.1 - 1.6e-21 76.1 4.6 2.3e-20 72.4 2.5 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 EIW72206.1 - 1.1e-10 41.1 0.0 1.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.1 EIW72206.1 - 7.6e-09 35.2 8.3 7.6e-09 35.2 5.8 2.3 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 EIW72206.1 - 0.00012 21.7 4.8 0.00012 21.7 3.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW72206.1 - 0.00015 21.3 5.4 0.00015 21.3 3.7 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW72206.1 - 0.00017 21.1 17.2 0.00024 20.7 3.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW72206.1 - 0.00021 20.9 2.1 0.00033 20.3 0.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EIW72206.1 - 0.00036 20.5 7.2 0.00036 20.5 5.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) CENP-F_leu_zip PF10473.4 EIW72206.1 - 0.0052 16.6 13.8 0.0052 16.6 9.6 1.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RRM_6 PF14259.1 EIW72206.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-rbx1 PF12678.2 EIW72206.1 - 0.024 14.7 2.8 0.024 14.7 1.9 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EIW72206.1 - 0.066 12.8 5.4 0.14 11.7 3.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Exonuc_VII_L PF02601.10 EIW72206.1 - 0.34 10.0 6.9 0.47 9.5 4.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-Q PF13094.1 EIW72206.1 - 0.42 10.6 13.4 1.1 9.2 9.3 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ERM PF00769.14 EIW72206.1 - 1.1 8.6 16.7 2 7.9 11.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4404 PF14357.1 EIW72206.1 - 1.4 9.3 12.5 0.19 12.1 1.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Macoilin PF09726.4 EIW72206.1 - 2 6.6 11.0 2.7 6.1 7.6 1.1 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 EIW72206.1 - 9.4 5.7 14.9 29 4.2 9.4 2.0 1 1 0 1 1 1 0 IncA protein Alpha-amylase PF00128.19 EIW72207.1 - 6.6e-33 114.4 1.1 1.3e-32 113.4 0.7 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EIW72207.1 - 8.7e-06 25.7 0.0 2.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_70 PF02324.11 EIW72207.1 - 2.2e-05 22.4 0.1 0.073 10.8 0.0 3.0 2 1 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.5 EIW72207.1 - 0.0001 22.0 0.3 0.00041 20.1 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Retrotrans_gag PF03732.12 EIW72210.1 - 0.00025 21.0 0.0 0.00025 21.0 0.0 2.4 2 1 0 2 2 2 1 Retrotransposon gag protein TPR_MLP1_2 PF07926.7 EIW72210.1 - 0.00097 18.8 5.1 0.0016 18.1 3.5 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 EIW72210.1 - 0.0074 15.9 6.3 0.013 15.1 4.4 1.3 1 0 0 1 1 1 1 IncA protein MalF_P2 PF14785.1 EIW72210.1 - 0.11 12.3 4.4 0.26 11.1 3.1 1.6 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Spc7 PF08317.6 EIW72210.1 - 0.21 10.1 6.6 0.35 9.4 4.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Herpes_LMP2 PF07415.6 EIW72210.1 - 0.93 8.0 2.6 1.6 7.2 1.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Atg14 PF10186.4 EIW72210.1 - 2.2 7.1 12.2 0.61 8.9 6.3 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BBP1_C PF15272.1 EIW72210.1 - 4.8 6.6 12.3 0.33 10.4 4.1 1.9 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal FUSC PF04632.7 EIW72210.1 - 5.9 5.1 11.0 8.3 4.6 7.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 EIW72210.1 - 9.4 6.6 8.3 25 5.2 5.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) zf-CCHC_3 PF13917.1 EIW72211.1 - 0.11 12.2 0.1 0.44 10.3 0.0 1.9 1 1 0 1 1 1 0 Zinc knuckle RVP PF00077.15 EIW72211.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.18 EIW72212.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW72212.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW72212.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.20 EIW72215.1 - 5e-42 143.8 0.0 7.5e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72215.1 - 3.7e-25 88.4 0.0 4.8e-24 84.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW72215.1 - 0.038 13.7 0.5 0.63 9.7 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EIW72215.1 - 0.057 12.4 0.1 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIW72215.1 - 0.3 9.8 0.0 0.44 9.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Josephin PF02099.12 EIW72216.1 - 2.5e-53 179.9 0.1 3.8e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Josephin UIM PF02809.15 EIW72216.1 - 0.025 14.0 4.8 0.025 14.0 3.3 2.7 3 0 0 3 3 3 0 Ubiquitin interaction motif CASP_C PF08172.7 EIW72217.1 - 9.5e-67 224.6 0.0 9.5e-67 224.6 0.0 4.7 2 1 1 3 3 3 1 CASP C terminal CtIP_N PF10482.4 EIW72217.1 - 0.0046 16.7 0.8 0.0046 16.7 0.6 6.2 4 1 3 7 7 7 1 Tumour-suppressor protein CtIP N-terminal domain XhlA PF10779.4 EIW72217.1 - 0.4 10.6 0.1 0.4 10.6 0.0 6.8 6 2 2 8 8 8 0 Haemolysin XhlA Flu_NS2 PF00601.14 EIW72217.1 - 0.48 10.6 10.2 1.3 9.2 0.1 3.7 3 1 1 4 4 4 0 Influenza non-structural protein (NS2) IncA PF04156.9 EIW72217.1 - 1 8.9 76.7 0.52 9.8 1.7 5.7 3 1 3 6 6 6 0 IncA protein Sfi1 PF08457.5 EIW72218.1 - 1.6e-44 152.2 99.7 6.8e-31 107.3 37.5 4.1 1 1 3 4 4 4 4 Sfi1 spindle body protein Peptidase_C65 PF10275.4 EIW72219.1 - 2.2e-60 204.0 0.0 3e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EIW72219.1 - 0.00083 19.9 0.0 1.3 9.6 0.0 2.3 1 1 1 2 2 2 2 OTU-like cysteine protease DUF3361 PF11841.3 EIW72219.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Vma12 PF11712.3 EIW72220.1 - 4.4e-17 62.1 0.6 7.7e-16 58.0 0.2 2.1 1 1 1 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4267 PF14087.1 EIW72220.1 - 0.021 14.3 0.3 0.039 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) Pro_isomerase PF00160.16 EIW72221.1 - 1.8e-43 148.4 0.1 2.9e-43 147.7 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRAP_alpha PF03896.11 EIW72221.1 - 9.1 5.1 6.7 14 4.5 4.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit adh_short_C2 PF13561.1 EIW72222.1 - 7e-32 111.1 0.0 9.7e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW72222.1 - 2.8e-23 82.6 0.5 3.8e-23 82.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW72222.1 - 4.3e-12 46.0 0.1 6e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 KR domain PA PF02225.17 EIW72222.1 - 0.029 14.0 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 PA domain His_biosynth PF00977.16 EIW72222.1 - 0.035 13.3 0.0 0.076 12.2 0.0 1.5 2 0 0 2 2 2 0 Histidine biosynthesis protein Rifin_STEVOR PF02009.11 EIW72224.1 - 0.0031 17.1 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family DUF4328 PF14219.1 EIW72224.1 - 0.058 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) SAP PF02037.22 EIW72225.1 - 4.7e-09 35.5 2.8 4.7e-09 35.5 2.0 1.9 2 0 0 2 2 2 1 SAP domain Sigma70_r1_1 PF03979.9 EIW72225.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 DUF4415 PF14384.1 EIW72225.1 - 0.49 10.6 2.4 24 5.1 1.5 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4415) HeH PF12949.2 EIW72225.1 - 0.83 9.2 7.6 0.59 9.7 2.3 2.7 2 1 0 2 2 2 0 HeH/LEM domain GATA PF00320.22 EIW72226.1 - 5.1e-07 28.9 0.8 9.8e-07 28.0 0.5 1.5 1 0 0 1 1 1 1 GATA zinc finger Peptidase_M48 PF01435.13 EIW72227.1 - 4.8e-27 94.9 0.0 7.2e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.1 EIW72227.1 - 0.019 14.1 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain ABM PF03992.11 EIW72228.1 - 6.7e-07 29.2 0.0 8.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SelP_N PF04592.9 EIW72228.1 - 0.0045 16.3 0.2 0.0048 16.3 0.1 1.0 1 0 0 1 1 1 1 Selenoprotein P, N terminal region ComX PF05952.7 EIW72228.1 - 0.039 13.4 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Bacillus competence pheromone ComX RhoGEF PF00621.15 EIW72229.1 - 4.4e-36 124.4 0.0 8.7e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 EIW72229.1 - 1.2e-22 80.3 0.1 3.6e-22 78.7 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EIW72229.1 - 0.0036 17.3 0.1 0.084 12.9 0.0 2.8 2 1 0 2 2 2 1 CDC24 Calponin She9_MDM33 PF05546.6 EIW72229.1 - 0.046 13.2 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 She9 / Mdm33 family RhoGAP PF00620.22 EIW72231.1 - 1.7e-43 147.8 0.0 4.3e-43 146.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain C1_1 PF00130.17 EIW72231.1 - 2.9e-08 33.2 9.7 4.6e-08 32.6 6.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2130 PF09903.4 EIW72231.1 - 0.023 13.4 3.9 0.034 12.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) NPV_P10 PF05531.7 EIW72231.1 - 0.023 14.9 1.4 8.1 6.7 0.2 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EIW72231.1 - 0.03 14.0 21.8 13 5.5 15.1 2.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2443 PF10398.4 EIW72231.1 - 0.055 13.2 0.5 1.3 8.8 0.1 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF2443) Sec34 PF04136.10 EIW72231.1 - 0.11 12.1 1.6 1.2 8.8 0.0 2.6 2 1 0 2 2 2 0 Sec34-like family TMF_TATA_bd PF12325.3 EIW72231.1 - 0.11 12.1 22.0 0.25 11.0 4.1 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Prok-RING_1 PF14446.1 EIW72231.1 - 0.13 11.9 6.5 0.22 11.2 4.5 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF972 PF06156.8 EIW72231.1 - 0.17 12.2 14.9 0.14 12.5 1.8 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 EIW72231.1 - 0.53 10.3 17.9 3.1 7.8 2.7 3.8 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Nup88 PF10168.4 EIW72231.1 - 0.53 8.0 9.8 0.078 10.8 2.9 1.9 1 1 1 2 2 2 0 Nuclear pore component IncA PF04156.9 EIW72231.1 - 0.63 9.5 26.4 0.45 10.0 3.0 2.3 1 1 1 2 2 2 0 IncA protein DUF904 PF06005.7 EIW72231.1 - 1.2 9.4 22.3 2.5 8.4 3.8 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF904) DUF4200 PF13863.1 EIW72231.1 - 1.3 9.0 20.3 0.067 13.1 0.9 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) APG6 PF04111.7 EIW72231.1 - 2.4 7.1 21.1 0.99 8.3 4.4 2.2 1 1 0 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EIW72231.1 - 2.7 7.8 22.0 0.38 10.5 4.7 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 EIW72231.1 - 2.9 7.9 15.3 5 7.1 4.0 3.0 2 2 0 2 2 2 0 DivIVA protein BLOC1_2 PF10046.4 EIW72231.1 - 3.2 7.9 7.0 21 5.2 0.1 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.1 EIW72231.1 - 3.9 6.3 16.9 0.64 8.9 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Prominin PF05478.6 EIW72231.1 - 4.3 4.7 6.0 2.8 5.3 2.5 1.8 1 1 0 1 1 1 0 Prominin Fib_alpha PF08702.5 EIW72231.1 - 5.3 7.1 6.7 6.3 6.9 0.8 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF605 PF04652.11 EIW72232.1 - 0.14 11.5 14.7 0.2 11.0 10.2 1.3 1 0 0 1 1 1 0 Vta1 like Daxx PF03344.10 EIW72232.1 - 0.32 9.4 39.6 0.099 11.1 25.5 1.4 1 1 0 1 1 1 0 Daxx Family DUF2624 PF11116.3 EIW72234.1 - 0.087 13.3 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) Spt4 PF06093.8 EIW72235.1 - 4.3e-32 109.8 0.1 5.1e-32 109.5 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger SART-1 PF03343.8 EIW72236.1 - 1.1e-125 420.3 61.9 1.3e-125 420.1 42.9 1.0 1 0 0 1 1 1 1 SART-1 family Yip1 PF04893.12 EIW72237.1 - 0.052 13.0 0.1 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain zf-RING_2 PF13639.1 EIW72238.1 - 1.9e-09 37.2 5.0 1.9e-09 37.2 3.5 2.9 3 0 0 3 3 2 1 Ring finger domain zf-TRAF PF02176.13 EIW72238.1 - 5.1e-09 36.3 11.4 0.00076 19.8 2.4 3.5 2 1 1 3 3 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EIW72238.1 - 6.2e-09 35.7 5.1 6.2e-09 35.7 3.5 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW72238.1 - 1.1e-08 34.5 6.4 1.1e-08 34.5 4.4 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EIW72238.1 - 2.1e-06 27.1 3.1 5.6e-06 25.7 2.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EIW72238.1 - 2.8e-06 26.9 4.4 2.8e-06 26.9 3.0 2.4 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW72238.1 - 3.9e-06 26.4 4.0 3.9e-06 26.4 2.7 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 EIW72238.1 - 6.7e-05 22.7 0.3 0.00063 19.6 0.1 2.7 3 0 0 3 3 3 1 U-box domain zf-RING_6 PF14835.1 EIW72238.1 - 0.00011 21.9 0.8 0.00011 21.9 0.6 2.0 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EIW72238.1 - 0.00011 22.2 0.9 0.00011 22.2 0.6 3.0 3 0 0 3 3 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EIW72238.1 - 0.0003 20.6 4.8 0.0003 20.6 3.3 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIW72238.1 - 0.0024 17.5 5.0 0.0067 16.1 3.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Sina PF03145.11 EIW72238.1 - 0.0058 16.3 0.3 0.0058 16.3 0.2 2.3 2 0 0 2 2 2 1 Seven in absentia protein family DUF1272 PF06906.6 EIW72238.1 - 0.12 12.2 10.7 0.87 9.4 3.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF2757 PF10955.3 EIW72238.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.9 3 1 0 3 3 2 0 Protein of unknown function (DUF2757) zf-Apc11 PF12861.2 EIW72238.1 - 1.4 8.8 10.3 0.11 12.3 0.2 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EIW72238.1 - 2.6 7.7 7.3 0.5 9.9 2.4 1.9 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EIW72238.1 - 5.2 6.6 12.8 0.37 10.3 3.3 2.9 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-CCHC PF00098.18 EIW72239.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW72239.1 - 0.33 11.1 8.4 0.087 13.0 3.7 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW72239.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) HSF_DNA-bind PF00447.12 EIW72241.1 - 2.6e-29 101.4 0.0 4e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Glyoxalase_5 PF14696.1 EIW72242.1 - 0.13 12.1 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF1690 PF07956.6 EIW72243.1 - 6.2e-17 61.8 0.9 8e-17 61.5 0.6 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Borrelia_P83 PF05262.6 EIW72243.1 - 0.014 13.6 1.2 0.016 13.5 0.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3826 PF12875.2 EIW72243.1 - 0.037 13.7 0.1 0.056 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) HSCB_C PF07743.8 EIW72243.1 - 0.05 14.0 7.5 1.5 9.3 0.6 2.4 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF883 PF05957.8 EIW72243.1 - 0.34 11.3 3.0 0.25 11.7 0.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Syntaxin PF00804.20 EIW72243.1 - 0.76 9.9 6.0 6.1 7.0 0.1 2.4 2 1 1 3 3 3 0 Syntaxin DUF455 PF04305.9 EIW72244.1 - 1.7e-99 332.2 0.0 2.1e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 EIW72244.1 - 5.9e-09 35.3 0.1 1.2e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EIW72244.1 - 5.8e-05 22.7 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DOCK-C2 PF14429.1 EIW72245.1 - 4.2e-35 121.0 0.0 7.7e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EIW72245.1 - 1.4e-16 60.3 0.0 2.9e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis Cript PF10235.4 EIW72246.1 - 6.8e-09 35.9 4.8 4.4e-07 30.1 3.3 2.1 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT zf-dskA_traR PF01258.12 EIW72246.1 - 0.016 14.9 0.5 0.76 9.5 0.0 2.3 2 1 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Actin PF00022.14 EIW72247.1 - 2e-117 391.9 0.0 2.6e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Actin Pkinase PF00069.20 EIW72248.1 - 3.1e-54 183.8 0.1 7.7e-54 182.5 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72248.1 - 5.3e-21 74.8 0.0 7.9e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW72248.1 - 0.00032 20.4 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family 6PF2K PF01591.13 EIW72248.1 - 0.004 16.2 0.2 0.011 14.8 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase RIO1 PF01163.17 EIW72248.1 - 0.0074 15.6 0.1 0.014 14.7 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EIW72248.1 - 0.24 10.9 2.5 0.12 11.9 0.3 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Glyco_transf_8 PF01501.15 EIW72249.1 - 1.6e-11 44.0 0.0 3.2e-11 43.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EIW72249.1 - 3.9e-05 23.5 0.3 5.5e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF382 PF04037.8 EIW72250.1 - 7.4e-59 197.1 0.1 2e-58 195.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EIW72250.1 - 1.2e-19 69.3 5.4 1.2e-19 69.3 3.7 2.0 2 0 0 2 2 2 1 PSP Nucleoplasmin PF03066.10 EIW72250.1 - 8.8 5.8 11.7 4.1 6.9 3.8 2.5 2 0 0 2 2 2 0 Nucleoplasmin TAP_C PF03943.8 EIW72251.1 - 9.7e-12 44.1 0.0 2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain MDMPI_N PF11716.3 EIW72251.1 - 0.008 16.6 1.1 0.13 12.7 0.3 2.3 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain UBA_4 PF14555.1 EIW72251.1 - 0.04 13.4 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain Oxysterol_BP PF01237.13 EIW72252.1 - 8.5e-113 376.4 0.0 1.2e-112 375.8 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.1 EIW72252.1 - 3.7e-16 58.7 0.2 6.2e-08 32.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EIW72252.1 - 1.4e-10 40.4 1.2 0.0021 17.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EIW72252.1 - 2.4e-10 40.5 0.1 5.5e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIW72252.1 - 1.1e-09 38.5 0.1 0.0062 17.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.24 EIW72252.1 - 2.3e-09 37.3 0.0 5.2e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EIW72252.1 - 6.3e-09 36.0 0.1 1.7e-08 34.6 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_3 PF13606.1 EIW72252.1 - 5.8e-07 29.1 0.1 0.059 13.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.1 EIW72252.1 - 0.00075 19.5 0.6 0.002 18.1 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain zf-DHHC PF01529.15 EIW72253.1 - 1.4e-17 63.6 0.4 3.6e-17 62.2 0.1 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase QLQ PF08880.6 EIW72253.1 - 0.03 13.7 1.0 0.066 12.6 0.7 1.6 1 0 0 1 1 1 0 QLQ GWT1 PF06423.7 EIW72255.1 - 2.9e-35 121.3 1.6 2.9e-35 121.3 1.1 2.7 2 1 0 2 2 2 1 GWT1 DUF1129 PF06570.6 EIW72255.1 - 0.079 12.2 0.1 0.65 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RNase_H2-Ydr279 PF09468.5 EIW72256.1 - 3.1e-40 138.2 0.0 3.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) GFA PF04828.9 EIW72257.1 - 0.00067 19.5 0.5 0.0073 16.2 0.6 1.9 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 EIW72257.1 - 0.036 13.7 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Rpr2 PF04032.11 EIW72257.1 - 0.11 12.3 0.3 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain SET PF00856.23 EIW72258.1 - 0.0015 18.8 0.0 0.0074 16.6 0.0 1.9 1 1 1 2 2 2 1 SET domain PI31_Prot_C PF08577.6 EIW72258.1 - 0.03 14.9 0.0 0.055 14.1 0.0 1.4 1 0 0 1 1 1 0 PI31 proteasome regulator FANCI_S1-cap PF14674.1 EIW72258.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 FANCI solenoid 1 cap MFS_1 PF07690.11 EIW72259.1 - 1.9e-25 89.3 59.6 3.7e-23 81.7 20.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW72259.1 - 1.6e-09 36.9 3.1 1.6e-09 36.9 2.1 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EIW72259.1 - 0.00029 20.5 2.7 0.076 12.8 0.3 2.8 2 0 0 2 2 2 2 MFS_1 like family TerC PF03741.11 EIW72259.1 - 0.044 13.2 1.7 0.12 11.8 1.2 1.6 1 0 0 1 1 1 0 Integral membrane protein TerC family MFS_1 PF07690.11 EIW72260.1 - 5.9e-21 74.5 26.3 5.9e-21 74.5 18.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW72260.1 - 1.1e-06 27.5 22.0 9.6e-05 21.1 12.4 3.3 1 1 1 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.13 EIW72261.1 - 3.3e-28 98.2 0.0 6e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW72261.1 - 0.00011 22.0 4.7 0.00029 20.6 3.3 1.7 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ndc1_Nup PF09531.5 EIW72261.1 - 1.4 7.2 9.7 3.1 6.0 6.7 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC27 PF09507.5 EIW72261.1 - 6.4 5.8 15.1 9.6 5.2 10.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HEAT PF02985.17 EIW72262.1 - 2.3e-11 42.7 1.1 0.029 14.4 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EIW72262.1 - 1.3e-05 25.3 0.2 0.1 12.8 0.0 3.1 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EIW72262.1 - 0.00078 19.8 2.7 0.22 12.0 0.1 4.4 4 1 1 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIW72262.1 - 0.0029 17.9 0.1 0.49 10.8 0.0 2.4 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EIW72262.1 - 0.015 15.1 0.1 0.81 9.5 0.0 2.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Tic20 PF09685.5 EIW72262.1 - 0.1 12.5 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Tic20-like protein Pkinase PF00069.20 EIW72262.1 - 0.24 10.5 0.0 0.62 9.1 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain GATase_5 PF13507.1 EIW72263.1 - 6.3e-88 294.0 0.1 2e-52 177.6 0.0 2.4 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EIW72263.1 - 4.3e-46 156.7 0.2 6e-26 91.2 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EIW72263.1 - 4.1e-24 84.6 2.1 4.6e-24 84.4 0.0 2.3 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain MRP-L20 PF12824.2 EIW72265.1 - 0.00074 19.5 4.1 0.00074 19.5 2.9 2.9 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 RRM_1 PF00076.17 EIW72267.1 - 2.4e-19 68.7 0.0 3.2e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW72267.1 - 2.4e-11 43.4 0.0 3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW72267.1 - 4.8e-09 35.9 0.0 7.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW72267.1 - 0.042 13.6 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 EIW72267.1 - 0.098 12.1 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease B OB domain Ribosomal_L18e PF00828.14 EIW72268.1 - 7.2e-17 61.9 0.0 1.1e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Polyoma_lg_T_C PF06431.6 EIW72268.1 - 0.086 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus tRNA-synt_2 PF00152.15 EIW72269.1 - 5.8e-88 294.8 0.1 8.4e-88 294.3 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIW72269.1 - 1.2e-12 47.5 0.0 2.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EIW72269.1 - 5e-10 38.9 0.5 4.2e-06 26.1 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EIW72269.1 - 0.064 12.8 0.1 6.9 6.2 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) FAR1 PF03101.10 EIW72270.1 - 0.0011 19.4 1.1 0.0011 19.4 0.8 1.8 2 0 0 2 2 2 1 FAR1 DNA-binding domain Fe_hyd_lg_C PF02906.9 EIW72271.1 - 4.4e-62 209.9 0.0 1.4e-61 208.3 0.0 1.9 2 1 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain CDK2AP PF09806.4 EIW72272.1 - 0.066 13.4 1.5 0.11 12.6 1.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Ashwin PF15323.1 EIW72272.1 - 0.45 10.4 9.2 0.029 14.3 2.7 1.6 2 0 0 2 2 2 0 Developmental protein Nop14 PF04147.7 EIW72272.1 - 0.96 7.2 4.2 1.2 6.9 2.9 1.0 1 0 0 1 1 1 0 Nop14-like family Pap_E4 PF02711.9 EIW72272.1 - 7.8 7.3 14.9 0.3 11.9 1.1 3.2 3 0 0 3 3 3 0 E4 protein BUD22 PF09073.5 EIW72272.1 - 10 5.0 12.7 14 4.5 8.8 1.1 1 0 0 1 1 1 0 BUD22 Internalin_N PF12354.3 EIW72274.1 - 0.2 11.3 1.5 0.24 11.0 0.1 1.9 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal C2 PF00168.25 EIW72275.1 - 2.9e-26 91.1 0.0 9.9e-18 63.7 0.0 2.6 2 0 0 2 2 2 2 C2 domain Gar1 PF04410.9 EIW72277.1 - 1.4e-38 131.7 0.0 2.2e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF3716 PF12511.3 EIW72279.1 - 0.12 12.0 6.0 0.21 11.2 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Pkinase PF00069.20 EIW72280.1 - 9.5e-73 244.5 0.0 1.2e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72280.1 - 6e-31 107.4 0.0 8.1e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIW72280.1 - 0.0012 17.9 0.2 0.0019 17.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIW72280.1 - 0.002 17.1 0.0 0.004 16.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW72280.1 - 0.017 14.8 0.1 0.32 10.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family RelB PF04221.7 EIW72280.1 - 0.062 13.0 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 RelB antitoxin SNF2_N PF00176.18 EIW72281.1 - 1.8e-65 220.7 0.0 2.7e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW72281.1 - 3.1e-13 49.3 0.0 7.7e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EIW72281.1 - 1.7e-06 27.7 4.8 1.7e-06 27.7 3.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EIW72281.1 - 3.5e-06 26.5 3.0 3.5e-06 26.5 2.1 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW72281.1 - 5.2e-06 26.3 3.5 5.2e-06 26.3 2.5 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EIW72281.1 - 1.6e-05 24.7 0.0 4.6e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 EIW72281.1 - 5.3e-05 22.8 3.4 5.3e-05 22.8 2.4 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EIW72281.1 - 5.4e-05 22.7 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-rbx1 PF12678.2 EIW72281.1 - 0.00017 21.5 2.3 0.00049 20.1 1.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 EIW72281.1 - 0.00045 19.6 2.0 0.0012 18.2 1.4 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EIW72281.1 - 0.0014 18.4 1.1 0.0044 16.8 0.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EIW72281.1 - 0.0088 15.7 4.0 0.0088 15.7 2.8 2.5 2 1 0 2 2 1 1 zinc-RING finger domain Zn_Tnp_IS91 PF14319.1 EIW72281.1 - 0.9 9.0 10.6 0.1 12.1 2.1 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Phage_head_fibr PF11133.3 EIW72282.1 - 0.11 11.6 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Head fiber protein DEAD PF00270.24 EIW72283.1 - 1.4e-47 161.2 0.0 1.9e-45 154.3 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW72283.1 - 1.9e-23 82.1 0.0 4.4e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW72283.1 - 0.0019 18.0 0.1 0.0083 15.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIW72283.1 - 0.085 11.9 0.0 0.085 11.9 0.0 3.0 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF1675 PF07897.6 EIW72283.1 - 3.8 7.2 12.5 6.1 6.6 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF481 PF04338.7 EIW72284.1 - 0.2 11.3 10.9 0.4 10.3 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF481 Calreticulin PF00262.13 EIW72285.1 - 3.2e-155 516.3 9.0 4e-155 515.9 6.3 1.1 1 0 0 1 1 1 1 Calreticulin family IPP-2 PF04979.9 EIW72286.1 - 1.6e-11 44.6 2.0 3.2e-05 24.1 0.2 2.3 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DUF1708 PF08101.6 EIW72287.1 - 2e-20 73.0 0.2 1.1e-19 70.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 EIW72287.1 - 1.3e-05 24.8 0.0 6.5e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 RhoGAP domain DUF2985 PF11204.3 EIW72288.1 - 4.6e-27 93.5 3.7 8.3e-27 92.7 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF1469 PF07332.6 EIW72288.1 - 1.4 8.6 4.8 0.79 9.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Transgly_assoc PF04226.8 EIW72288.1 - 3 7.9 7.9 2.1 8.5 2.4 2.2 2 0 0 2 2 2 0 Transglycosylase associated protein PTPLA PF04387.9 EIW72289.1 - 1.8e-43 147.8 11.8 1.8e-43 147.8 8.2 2.6 2 1 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA DUF3189 PF11385.3 EIW72292.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3189) eIF-5_eIF-2B PF01873.12 EIW72295.1 - 2.3e-46 156.5 0.3 3.4e-46 155.9 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EIW72295.1 - 0.0028 16.9 0.1 0.005 16.1 0.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding ATP-synt PF00231.14 EIW72296.1 - 2.6e-69 233.7 3.2 3e-69 233.5 2.2 1.0 1 0 0 1 1 1 1 ATP synthase DUF3921 PF13060.1 EIW72296.1 - 0.038 13.8 0.0 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3921) Formyl_trans_N PF00551.14 EIW72297.1 - 4.8e-08 32.7 0.0 2.4e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Formyl transferase ECH PF00378.15 EIW72297.1 - 8.4e-06 25.0 0.1 0.00046 19.3 0.1 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Mre11_DNA_bind PF04152.9 EIW72298.1 - 1.2e-47 162.0 0.8 1.2e-47 162.0 0.6 2.3 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EIW72298.1 - 8.8e-22 77.4 1.1 2.7e-21 75.8 0.7 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW72298.1 - 1.5e-06 28.1 0.2 9e-06 25.6 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Nse4_C PF08743.5 EIW72299.1 - 6.2e-29 99.8 0.3 1.4e-28 98.7 0.2 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EIW72299.1 - 2.8e-12 46.3 2.5 7.8e-12 44.8 1.7 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE RRM_5 PF13893.1 EIW72299.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 EIW72300.1 - 2.4e-44 151.2 0.0 2.7e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PhoD PF09423.5 EIW72301.1 - 0.00054 18.6 0.1 0.013 14.0 0.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase DSBA PF01323.15 EIW72303.1 - 5.9e-12 45.5 0.0 2.1e-11 43.7 0.0 1.8 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EIW72303.1 - 0.1 12.8 0.0 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like domain DUF3115 PF11312.3 EIW72304.1 - 4.9e-12 45.3 2.2 7.3e-12 44.7 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) DUF3115 PF11312.3 EIW72305.1 - 6.9e-18 64.5 0.0 8.1e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Peptidase_S10 PF00450.17 EIW72306.1 - 7.1e-90 302.1 0.0 9.1e-90 301.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIW72306.1 - 0.0026 17.6 0.3 0.061 13.1 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family RNA_pol_Rpc4 PF05132.9 EIW72308.1 - 1.4e-20 73.6 0.2 1.4e-20 73.6 0.1 2.6 2 2 0 2 2 2 1 RNA polymerase III RPC4 Shadoo PF14999.1 EIW72308.1 - 0.046 13.5 3.1 0.098 12.5 2.2 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective TFIIF_alpha PF05793.7 EIW72308.1 - 4.8 5.4 13.9 6.6 4.9 9.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAGA_bind PF06217.7 EIW72309.1 - 0.017 15.1 2.1 0.021 14.8 1.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 EIW72309.1 - 1.3 8.1 9.5 2 7.5 6.6 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) zf-RING_5 PF14634.1 EIW72310.1 - 0.93 9.2 10.9 1.4 8.7 7.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Ist1 PF03398.9 EIW72311.1 - 4.1e-56 188.9 0.1 5.1e-56 188.6 0.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TAF PF02969.12 EIW72312.1 - 4.2e-20 71.4 0.0 2.5e-19 68.9 0.0 2.2 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 EIW72312.1 - 6.5e-17 61.4 0.0 1.4e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 EIW72312.1 - 8.1e-05 22.6 0.0 0.00033 20.7 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW72312.1 - 0.0022 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EIW72312.1 - 0.053 13.2 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 Bromodomain associated Delta_lysin PF05372.6 EIW72312.1 - 0.063 12.6 0.1 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Delta lysin family CENP-S PF15630.1 EIW72312.1 - 0.074 13.2 0.1 0.28 11.4 0.1 1.8 2 0 0 2 2 2 0 Kinetochore component CENP-S Fis1_TPR_C PF14853.1 EIW72313.1 - 4.5e-24 84.0 0.7 6.7e-24 83.5 0.5 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EIW72313.1 - 8.4e-14 50.5 0.0 1.4e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat COPI_C PF06957.6 EIW72313.1 - 0.026 13.0 0.0 0.037 12.5 0.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus PG_binding_3 PF09374.5 EIW72313.1 - 0.051 13.5 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Predicted Peptidoglycan domain DUF3074 PF11274.3 EIW72313.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) NST1 PF13945.1 EIW72313.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Mito_carr PF00153.22 EIW72314.1 - 1.2e-64 214.0 0.8 1.2e-21 76.2 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Pyrophosphatase PF00719.14 EIW72315.1 - 1.4e-53 180.5 0.1 1.7e-53 180.2 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase TSA PF03249.8 EIW72315.1 - 0.18 10.3 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Type specific antigen TatD_DNase PF01026.16 EIW72316.1 - 1.2e-15 57.3 0.1 5.8e-15 55.1 0.1 2.0 1 1 0 1 1 1 1 TatD related DNase Ank_2 PF12796.2 EIW72317.1 - 4.4e-52 174.3 0.7 6.1e-17 61.7 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EIW72317.1 - 1.5e-40 135.0 3.7 1.6e-05 24.4 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 EIW72317.1 - 8.2e-37 124.9 1.0 2.9e-13 49.9 0.0 4.9 4 1 2 6 6 6 5 Ankyrin repeats (many copies) SPX PF03105.14 EIW72317.1 - 2.3e-33 116.1 0.0 4e-31 108.8 0.0 2.4 1 1 0 1 1 1 1 SPX domain Ank_3 PF13606.1 EIW72317.1 - 4.1e-29 97.7 2.6 0.0022 18.0 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EIW72317.1 - 6.8e-23 80.1 8.7 0.00075 19.6 0.0 7.7 3 2 5 8 8 8 7 Ankyrin repeats (many copies) GDPD PF03009.12 EIW72317.1 - 8.1e-18 64.8 0.0 3.6e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Fructosamin_kin PF03881.9 EIW72318.1 - 4.8e-40 137.3 0.1 9.5e-39 133.0 0.1 2.0 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EIW72318.1 - 1.3e-07 31.6 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EIW72318.1 - 0.1 11.1 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RPN7 PF10602.4 EIW72319.1 - 3.8e-23 81.7 0.0 5.5e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EIW72319.1 - 4.5e-13 49.4 0.0 9.8e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EIW72319.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Fip1 PF05182.8 EIW72320.1 - 3e-16 58.4 0.4 5e-16 57.6 0.3 1.4 1 0 0 1 1 1 1 Fip1 motif Pribosyltran PF00156.22 EIW72321.1 - 1.4e-06 28.0 0.1 5e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF2205 PF10224.4 EIW72321.1 - 0.37 10.3 2.3 5.7 6.5 0.2 2.3 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Complex1_LYR_2 PF13233.1 EIW72322.1 - 5.2e-11 42.9 2.8 3.1e-10 40.4 2.0 1.9 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EIW72322.1 - 0.009 15.7 6.3 0.01 15.6 2.8 2.1 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Ribonuc_red_lgC PF02867.10 EIW72322.1 - 0.027 13.0 0.0 0.031 12.8 0.0 1.0 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain Complex1_LYR_1 PF13232.1 EIW72322.1 - 0.03 14.5 6.9 0.082 13.1 4.8 2.1 1 1 0 1 1 1 0 Complex1_LYR-like HTH_40 PF14493.1 EIW72322.1 - 0.13 12.5 0.1 0.81 9.9 0.1 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.11 EIW72326.1 - 3.2e-27 95.1 17.1 1.6e-26 92.9 12.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.13 EIW72326.1 - 0.0056 15.2 0.0 0.52 8.7 0.0 2.3 2 0 0 2 2 2 2 Reduced folate carrier UCH PF00443.24 EIW72327.1 - 3.8e-15 55.7 0.0 7.1e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW72327.1 - 1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MULE PF10551.4 EIW72327.1 - 2e-08 34.2 0.4 4.8e-07 29.8 0.3 2.5 1 1 0 1 1 1 1 MULE transposase domain Bystin PF05291.6 EIW72327.1 - 0.85 8.4 0.0 1.7 7.5 0.0 1.4 1 0 0 1 1 1 0 Bystin GAS PF13851.1 EIW72328.1 - 0.59 9.2 16.5 1.8 7.7 7.2 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EIW72328.1 - 0.86 9.4 23.7 2.2 8.1 12.5 2.7 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAGA_bind PF06217.7 EIW72328.1 - 1.1 9.1 6.7 1.5 8.7 4.0 1.5 1 1 0 1 1 1 0 GAGA binding protein-like family ATG16 PF08614.6 EIW72328.1 - 2 8.2 24.6 0.071 12.9 6.0 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Uds1 PF15456.1 EIW72328.1 - 4.1 7.4 18.0 1.2 9.1 9.9 2.0 1 1 0 2 2 2 0 Up-regulated During Septation DUF1664 PF07889.7 EIW72328.1 - 5.5 6.8 7.8 1 9.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.6 EIW72328.1 - 9.2 5.9 8.7 3.7 7.2 1.4 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.3 EIW72328.1 - 9.9 6.0 19.2 5.4 6.9 2.6 2.5 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fungal_trans PF04082.13 EIW72329.1 - 2e-20 72.7 1.0 1.7e-19 69.7 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW72329.1 - 1.1e-05 25.2 10.6 2.2e-05 24.2 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1445 PF07286.7 EIW72330.1 - 1.2e-51 174.1 0.0 1.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Hydantoinase_B PF02538.9 EIW72331.1 - 7.5e-189 628.3 0.0 1e-188 627.8 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EIW72331.1 - 6.1e-87 291.4 0.1 1e-86 290.6 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIW72331.1 - 9e-50 168.6 0.6 1.8e-47 161.0 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.6 EIW72331.1 - 0.34 9.7 0.1 0.64 8.8 0.1 1.3 1 0 0 1 1 1 0 StbA protein Shisa PF13908.1 EIW72332.1 - 0.00031 20.9 0.0 0.00031 20.9 0.0 4.8 2 2 2 4 4 4 1 Wnt and FGF inhibitory regulator SKG6 PF08693.5 EIW72332.1 - 0.0078 15.5 4.2 0.026 13.8 2.9 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2029 PF09594.5 EIW72332.1 - 0.075 12.5 0.1 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) VD10_N PF08476.5 EIW72332.1 - 0.084 12.3 0.3 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Viral D10 N-terminal IncA PF04156.9 EIW72332.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 IncA protein EphA2_TM PF14575.1 EIW72332.1 - 0.19 12.1 0.1 0.4 11.0 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OppC_N PF12911.2 EIW72332.1 - 0.29 10.5 2.5 0.91 8.9 1.8 1.8 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DNA_ligase_A_M PF01068.16 EIW72333.1 - 5e-09 35.8 0.0 1.2e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 EIW72333.1 - 2.7e-05 23.7 0.0 6.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4248 PF14053.1 EIW72333.1 - 0.12 12.0 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) TauD PF02668.11 EIW72335.1 - 8.3e-51 173.1 0.0 1.1e-50 172.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.19 EIW72337.1 - 8.4e-102 341.0 19.7 9.4e-102 340.8 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW72337.1 - 4.6e-24 84.7 23.8 1e-18 67.1 2.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW72337.1 - 2.3e-07 29.3 3.2 2.3e-07 29.3 2.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Epimerase PF01370.16 EIW72338.1 - 1.5e-14 54.0 0.0 1.9e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW72338.1 - 1.2e-06 27.4 0.0 1.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW72338.1 - 8.9e-05 21.5 0.0 0.092 11.6 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EIW72338.1 - 0.00058 19.8 0.0 0.0025 17.7 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIW72338.1 - 0.029 13.2 0.0 0.057 12.3 0.0 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain Enterotoxin_a PF01375.12 EIW72338.1 - 0.038 13.2 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain Sirohm_synth_M PF14824.1 EIW72338.1 - 0.13 11.2 0.1 2 7.4 0.1 2.3 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central DAO PF01266.19 EIW72339.1 - 9.5e-26 90.5 0.4 1.8e-25 89.6 0.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW72339.1 - 2.8e-05 23.1 0.0 3.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW72339.1 - 6.9e-05 22.8 0.2 0.0002 21.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW72339.1 - 0.00022 20.4 0.2 0.00031 19.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW72339.1 - 0.00048 19.3 0.1 0.00082 18.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EIW72339.1 - 0.002 18.1 0.5 0.0041 17.1 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW72339.1 - 0.0097 16.2 0.7 0.029 14.7 0.5 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIW72339.1 - 0.013 14.3 0.2 0.022 13.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EIW72339.1 - 0.022 14.1 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 EIW72339.1 - 0.027 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain GIDA PF01134.17 EIW72339.1 - 0.05 12.4 0.1 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EIW72339.1 - 0.059 13.0 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EIW72339.1 - 0.083 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EIW72339.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Exo_endo_phos PF03372.18 EIW72340.1 - 4.7e-20 72.5 0.0 6.5e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sugar_tr PF00083.19 EIW72341.1 - 1.5e-87 294.0 26.0 1.8e-87 293.8 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW72341.1 - 4.6e-20 71.6 39.9 1.7e-11 43.4 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyridoxal_deC PF00282.14 EIW72342.1 - 1.4e-80 270.5 0.0 4e-80 269.0 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EIW72342.1 - 0.00019 20.6 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EIW72342.1 - 0.0066 15.2 0.0 0.024 13.3 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Transp_cyt_pur PF02133.10 EIW72344.1 - 2.8e-92 309.5 42.0 3.5e-92 309.2 29.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF952 PF06108.7 EIW72345.1 - 9.4e-11 41.4 0.0 1.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Glycos_transf_1 PF00534.15 EIW72346.1 - 3.1e-23 82.0 0.0 5.6e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIW72346.1 - 2.4e-10 40.7 1.3 7.9e-10 39.1 0.4 2.4 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EIW72346.1 - 3.2e-08 33.8 0.0 6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EIW72346.1 - 2e-07 30.9 0.0 4.2e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EIW72346.1 - 0.00032 20.8 0.0 0.0019 18.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 CLU PF13236.1 EIW72347.1 - 9e-61 205.1 0.0 1.5e-60 204.3 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EIW72347.1 - 1.4e-39 135.7 0.0 2.4e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EIW72347.1 - 2.2e-18 65.9 2.8 1.6e-11 43.9 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIW72347.1 - 1.5e-08 34.2 5.4 0.0016 18.2 0.1 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIW72347.1 - 0.0011 18.6 0.1 0.015 14.9 0.0 2.6 2 0 0 2 2 2 1 TPR repeat CLU_N PF15044.1 EIW72347.1 - 0.08 13.1 0.0 0.37 10.9 0.0 2.1 1 1 0 1 1 1 0 Mitochondrial function, CLU-N-term DUF727 PF05303.7 EIW72347.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF727) L27 PF02828.11 EIW72348.1 - 0.057 13.1 0.4 0.3 10.8 0.3 2.1 1 1 0 1 1 1 0 L27 domain FtsK_SpoIIIE PF01580.13 EIW72348.1 - 0.092 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Methyltransf_PK PF05891.7 EIW72350.1 - 1.9e-50 171.1 0.0 4.2e-20 71.9 0.0 3.3 3 1 0 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EIW72350.1 - 0.00072 20.1 0.0 0.0017 18.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW72350.1 - 0.0021 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW72350.1 - 0.0024 18.2 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EIW72350.1 - 0.028 14.8 0.0 8.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L32e PF01655.13 EIW72351.1 - 3.7e-49 165.3 1.2 4.4e-49 165.1 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Thioredoxin PF00085.15 EIW72352.1 - 1e-43 147.2 0.0 3.2e-23 81.4 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EIW72352.1 - 1.3e-33 116.3 0.0 1.1e-24 87.2 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EIW72352.1 - 2.2e-07 31.0 0.0 0.015 15.5 0.0 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIW72352.1 - 3.2e-06 27.1 0.0 0.0027 17.8 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EIW72352.1 - 0.00043 20.2 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like RVT_2 PF07727.9 EIW72356.1 - 6.5e-77 257.8 0.0 8.8e-77 257.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rick_17kDa_Anti PF05433.10 EIW72358.1 - 0.0056 16.3 6.3 0.0056 16.3 4.3 2.0 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EIW72358.1 - 3.8 7.2 16.6 0.024 14.2 5.1 2.1 2 0 0 2 2 2 0 Glycine zipper PET PF06297.9 EIW72359.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 PET Domain Ribosomal_L13 PF00572.13 EIW72360.1 - 6.9e-26 90.7 0.0 1.2e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 TPT PF03151.11 EIW72361.1 - 1.1e-24 86.8 14.7 9.2e-23 80.5 2.4 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EIW72361.1 - 2.9e-11 42.8 13.2 1.1e-10 40.8 9.2 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIW72361.1 - 5e-08 33.0 24.7 2e-05 24.6 7.3 2.8 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EIW72361.1 - 0.00017 21.7 15.4 0.0015 18.7 2.9 2.6 2 1 0 2 2 2 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EIW72361.1 - 0.021 13.9 5.5 0.082 11.9 1.4 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter DUF2648 PF10855.3 EIW72361.1 - 0.15 11.4 0.0 0.59 9.6 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) SGS PF05002.10 EIW72363.1 - 9.8e-25 86.1 0.0 1.7e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EIW72363.1 - 4.5e-11 43.1 0.0 7.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 CS domain DUF1170 PF06663.8 EIW72363.1 - 0.074 12.9 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) Diphthamide_syn PF01866.12 EIW72364.1 - 1.1e-50 172.7 0.0 1.6e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DDE_3 PF13358.1 EIW72365.1 - 2.8e-14 53.0 0.2 5.4e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EIW72365.1 - 4.8e-06 26.5 0.1 2.7e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EIW72365.1 - 0.00018 21.6 0.2 0.00093 19.3 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 EIW72365.1 - 0.00073 20.2 0.3 0.00073 20.2 0.2 3.0 3 1 0 3 3 3 1 Homeodomain-like domain MULE PF10551.4 EIW72365.1 - 0.071 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 MULE transposase domain VRR_NUC PF08774.6 EIW72366.1 - 2.1e-19 69.4 0.0 4.3e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain 2-ph_phosp PF04029.9 EIW72366.1 - 0.19 10.6 0.0 0.38 9.6 0.0 1.5 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase ETC_C1_NDUFA5 PF04716.9 EIW72367.1 - 7.6e-17 60.5 0.0 1.5e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Tropomyosin PF00261.15 EIW72367.1 - 0.028 13.5 0.5 0.035 13.1 0.4 1.0 1 0 0 1 1 1 0 Tropomyosin MIF4G PF02854.14 EIW72369.1 - 2.7e-22 79.2 0.0 4.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EIW72369.1 - 6.8e-13 48.3 0.1 2.5e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 MA3 domain XkdW PF09636.5 EIW72370.1 - 0.74 9.7 3.9 2.8 7.8 0.7 2.6 3 0 0 3 3 3 0 XkdW protein Mito_carr PF00153.22 EIW72371.1 - 1.8e-67 223.0 4.3 6.8e-25 86.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CS PF04969.11 EIW72372.1 - 3e-18 66.1 0.0 5.5e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 CS domain DUF1604 PF07713.8 EIW72375.1 - 0.1 12.4 0.1 0.36 10.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Ribosomal_L13e PF01294.13 EIW72376.1 - 4.7e-60 202.1 1.6 7.2e-60 201.5 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e WSK PF03832.8 EIW72376.1 - 4.9 6.5 17.6 0.57 9.5 1.6 3.8 3 0 0 3 3 3 0 WSK motif Mito_carr PF00153.22 EIW72377.1 - 1.7e-31 107.8 8.5 3.3e-14 52.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SAM_2 PF07647.12 EIW72378.1 - 2.8e-06 27.0 0.0 5.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIW72378.1 - 9.5e-06 25.6 0.1 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RRM_1 PF00076.17 EIW72379.1 - 1.6e-05 24.4 0.0 4.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW72379.1 - 5.8e-05 22.9 0.0 0.00068 19.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIW72379.1 - 0.025 14.3 0.1 0.06 13.2 0.0 1.7 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.1 EIW72379.1 - 0.026 14.3 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med7 PF05983.6 EIW72380.1 - 3.6e-17 62.6 0.0 4.7e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 MED7 protein SNF2_N PF00176.18 EIW72382.1 - 4.5e-50 170.1 0.1 1.1e-47 162.2 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW72382.1 - 2.6e-14 52.8 0.0 4.9e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain tRNA-synt_1 PF00133.17 EIW72383.1 - 2e-43 148.3 0.0 1.5e-33 115.7 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EIW72383.1 - 2.3e-20 72.6 1.0 5.6e-11 41.7 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EIW72383.1 - 2.2e-14 53.5 0.0 5.1e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EIW72383.1 - 8.8e-10 38.1 0.1 1.6e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EIW72383.1 - 0.068 11.8 0.0 0.15 10.6 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (K) HAD_2 PF13419.1 EIW72384.1 - 8.1e-21 75.0 0.0 9.8e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW72384.1 - 2e-12 47.9 0.0 5.1e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW72384.1 - 8.5e-10 38.2 0.0 1.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EIW72384.1 - 0.00076 19.6 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EIW72384.1 - 0.005 16.7 0.0 0.044 13.6 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DnaJ PF00226.26 EIW72385.1 - 1.2e-20 72.9 0.2 2e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EIW72385.1 - 0.011 15.7 0.9 0.016 15.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) SMN PF06003.7 EIW72386.1 - 4.1 6.4 11.4 4.1 6.4 3.2 2.7 2 1 1 3 3 3 0 Survival motor neuron protein (SMN) DUF846 PF05832.7 EIW72387.1 - 8.6e-56 187.5 5.9 1.1e-55 187.2 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) FA_desaturase PF00487.19 EIW72387.1 - 7.4 5.9 8.0 1.9 7.8 3.4 1.5 1 1 1 2 2 2 0 Fatty acid desaturase NRDE-2 PF08424.5 EIW72388.1 - 1.6e-72 244.1 8.5 4.9e-71 239.2 0.0 4.2 4 1 0 4 4 4 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EIW72388.1 - 0.022 15.3 1.9 21 6.1 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat RhoGEF PF00621.15 EIW72389.1 - 1.5e-61 207.4 0.7 6.7e-33 114.0 0.1 2.2 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.17 EIW72389.1 - 2e-38 132.4 0.0 2.6e-25 89.3 0.0 2.3 1 1 1 2 2 2 2 CNH domain PH_5 PF15405.1 EIW72389.1 - 3.2e-14 53.0 0.0 8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIW72389.1 - 0.05 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF3295 PF11702.3 EIW72389.1 - 0.26 10.2 6.5 0.42 9.5 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) UBN2_3 PF14244.1 EIW72390.1 - 8.8e-05 22.1 0.0 0.013 15.0 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW72390.1 - 0.00037 20.2 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIW72390.1 - 0.041 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Dapper PF15268.1 EIW72390.1 - 0.11 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Dapper Nop14 PF04147.7 EIW72391.1 - 6.3 4.5 5.9 8.9 4.0 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2587 PF10759.4 EIW72392.1 - 0.048 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) rve PF00665.21 EIW72393.1 - 2.9e-22 79.0 0.0 5.1e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIW72393.1 - 1.8e-09 37.1 0.5 3.7e-09 36.1 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIW72393.1 - 0.013 14.8 0.1 0.28 10.6 0.0 2.5 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger rve_3 PF13683.1 EIW72393.1 - 0.019 14.4 0.4 0.019 14.4 0.3 2.5 3 0 0 3 3 3 0 Integrase core domain CPSase_L_D2 PF02786.12 EIW72394.1 - 2e-106 353.9 0.0 1.5e-83 279.2 0.0 2.5 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EIW72394.1 - 8e-38 128.9 0.4 1.8e-37 127.8 0.3 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EIW72394.1 - 1.7e-36 125.7 0.2 4.7e-19 68.8 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 EIW72394.1 - 2.5e-36 124.1 0.0 1.3e-17 63.8 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EIW72394.1 - 2.8e-21 75.6 0.0 1.3e-09 37.2 0.0 4.8 4 1 0 4 4 4 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EIW72394.1 - 4.4e-15 55.4 0.0 2.7e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIW72394.1 - 5.7e-10 38.9 0.0 0.00083 18.7 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EIW72394.1 - 1e-05 25.1 0.0 0.0034 16.8 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain MGS PF02142.17 EIW72394.1 - 2.9e-05 23.9 0.1 0.00013 21.7 0.0 2.2 1 1 0 1 1 1 1 MGS-like domain ATP-grasp_5 PF13549.1 EIW72394.1 - 0.0012 18.0 0.0 1.3 8.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_M17_N PF02789.12 EIW72394.1 - 0.044 13.5 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Amidase PF01425.16 EIW72395.1 - 1.7e-91 307.3 0.0 1.9e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Pox_P35 PF03213.9 EIW72396.1 - 0.19 10.7 5.1 0.29 10.0 3.5 1.3 1 0 0 1 1 1 0 Poxvirus P35 protein HMG_box PF00505.14 EIW72397.1 - 0.018 15.2 0.3 0.68 10.2 0.0 2.6 2 0 0 2 2 2 0 HMG (high mobility group) box GILT PF03227.11 EIW72398.1 - 3.9e-11 42.7 0.2 7e-11 41.9 0.2 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) BORG_CEP PF14957.1 EIW72399.1 - 1.1 10.1 10.0 2.5 9.0 3.1 2.8 1 1 2 3 3 3 0 Cdc42 effector WD40 PF00400.27 EIW72401.1 - 1.1e-47 158.2 18.4 4.6e-12 45.3 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIW72401.1 - 0.00012 20.3 6.2 0.71 7.9 0.1 4.6 2 1 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW72401.1 - 0.00057 18.7 1.4 0.82 8.3 0.0 3.7 1 1 2 3 3 3 2 Nup133 N terminal like Gtr1_RagA PF04670.7 EIW72401.1 - 0.0097 15.0 0.0 2.2 7.3 0.0 2.4 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region DUF3312 PF11768.3 EIW72401.1 - 0.031 12.5 0.0 0.051 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DnaJ PF00226.26 EIW72402.1 - 1.4e-25 88.7 3.1 2.2e-25 88.1 2.1 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIW72402.1 - 2.2e-19 69.1 1.1 2.5e-17 62.5 0.1 2.7 2 1 0 2 2 2 2 DnaJ C terminal domain DUF3837 PF12939.2 EIW72402.1 - 0.017 15.1 0.2 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) CBFD_NFYB_HMF PF00808.18 EIW72403.1 - 0.019 14.9 0.1 0.43 10.6 0.0 2.6 2 1 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cyt-b5 PF00173.23 EIW72404.1 - 2.7e-13 49.5 0.0 3.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S8e PF01201.17 EIW72405.1 - 8.9e-35 119.7 8.3 3.8e-34 117.6 5.8 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 EIW72405.1 - 0.024 14.5 0.2 0.024 14.5 0.1 1.7 1 1 0 2 2 2 0 Mer2 G-patch PF01585.18 EIW72406.1 - 3.1e-06 26.8 0.0 7.2e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIW72406.1 - 0.11 12.3 0.1 0.11 12.3 0.0 2.6 3 0 0 3 3 3 0 DExH-box splicing factor binding site GTP_EFTU PF00009.22 EIW72407.1 - 3.4e-56 189.6 0.0 5.2e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIW72407.1 - 1.7e-36 124.3 0.3 4.9e-36 122.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIW72407.1 - 2e-16 59.8 0.5 2e-16 59.8 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIW72407.1 - 5.5e-05 22.7 0.6 0.00016 21.2 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EIW72407.1 - 0.0016 18.3 0.2 0.006 16.5 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase CRAL_TRIO PF00650.15 EIW72408.1 - 7.1e-19 67.8 0.0 9.2e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIW72408.1 - 0.0014 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SNARE_assoc PF09335.6 EIW72409.1 - 8.9e-11 42.0 15.2 9.1e-11 42.0 5.8 2.6 3 0 0 3 3 3 2 SNARE associated Golgi protein eIF-5_eIF-2B PF01873.12 EIW72410.1 - 1.4e-40 137.8 0.0 2.2e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EIW72410.1 - 2.7e-24 84.9 0.7 5.5e-24 83.9 0.5 1.5 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Cys_rich_CPXG PF14255.1 EIW72410.1 - 0.041 13.7 0.2 0.079 12.7 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG ox_reductase_C PF08635.5 EIW72411.1 - 1.3e-59 199.7 0.0 1.9e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EIW72411.1 - 8e-19 68.3 0.0 1.6e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TPP_enzyme_M PF00205.17 EIW72411.1 - 0.04 13.6 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DDE_1 PF03184.14 EIW72412.1 - 8.2e-30 103.5 0.0 1.2e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Na_H_Exchanger PF00999.16 EIW72414.1 - 2.8e-45 154.4 29.1 3.8e-45 154.0 20.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EIW72414.1 - 0.093 12.6 0.1 0.093 12.6 0.1 3.0 3 0 0 3 3 3 0 YrhC-like protein DUF3169 PF11368.3 EIW72414.1 - 0.54 9.4 5.0 0.2 10.8 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) GATA PF00320.22 EIW72416.1 - 4.7e-06 25.8 4.0 1e-05 24.7 2.8 1.6 1 0 0 1 1 1 1 GATA zinc finger Tubulin PF00091.20 EIW72417.1 - 3.9e-72 242.5 0.0 6.1e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIW72417.1 - 5e-48 162.3 0.1 8.3e-48 161.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIW72417.1 - 3.5e-06 27.0 0.0 7.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EIW72417.1 - 0.0036 16.8 0.0 0.0068 15.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Vps35 PF03635.12 EIW72419.1 - 0 1083.2 0.0 0 1082.9 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Daxx PF03344.10 EIW72419.1 - 3 6.2 7.5 5 5.4 5.2 1.2 1 0 0 1 1 1 0 Daxx Family EF_TS PF00889.14 EIW72420.1 - 1.7e-12 47.1 0.0 4.7e-08 32.6 0.0 2.4 2 1 0 2 2 2 2 Elongation factor TS MFS_1 PF07690.11 EIW72421.1 - 1.1e-50 172.3 41.1 7e-50 169.7 27.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW72421.1 - 2.9e-16 58.8 18.7 3.9e-16 58.3 13.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW72421.1 - 1.7e-09 36.7 15.3 1.7e-09 36.7 10.6 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter DUF983 PF06170.7 EIW72421.1 - 3.4 7.8 15.1 0.38 10.8 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF983) PLDc_2 PF13091.1 EIW72422.1 - 8.2e-19 67.6 0.0 8.7e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EIW72422.1 - 0.0033 17.1 0.3 0.41 10.5 0.0 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif PPR_2 PF13041.1 EIW72424.1 - 3.5e-16 58.9 0.0 5.1e-12 45.5 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 EIW72424.1 - 1e-05 25.3 0.1 0.0097 16.1 0.0 3.5 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 EIW72424.1 - 3.6e-05 23.4 0.4 0.0095 15.8 0.0 3.2 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.2 EIW72424.1 - 0.011 15.2 1.4 0.24 10.9 0.0 3.0 4 0 0 4 4 4 0 PPR repeat Chromo PF00385.19 EIW72425.1 - 4.5e-10 39.0 0.5 7.7e-10 38.2 0.3 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EIW72425.1 - 0.055 13.3 0.3 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DUF2587 PF10759.4 EIW72426.1 - 0.11 11.9 0.1 0.28 10.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) SR-25 PF10500.4 EIW72426.1 - 4.5 6.6 31.5 0.016 14.6 7.8 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_L6e PF01159.14 EIW72429.1 - 0.083 13.1 0.8 0.16 12.2 0.2 1.7 2 0 0 2 2 2 0 Ribosomal protein L6e ABM PF03992.11 EIW72432.1 - 0.055 13.5 0.4 0.088 12.8 0.3 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Peroxin-13_N PF04088.8 EIW72433.1 - 2.4e-44 151.0 0.0 4.2e-44 150.2 0.0 1.4 1 1 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 EIW72433.1 - 5.7e-11 41.8 0.4 5.7e-11 41.8 0.3 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EIW72433.1 - 1.3e-09 37.4 0.5 1.3e-09 37.4 0.4 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EIW72433.1 - 4.4e-08 32.3 5.2 4.5e-08 32.3 0.6 2.4 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.6 EIW72433.1 - 0.013 15.7 2.6 0.1 12.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain Na_Ca_ex PF01699.19 EIW72433.1 - 0.02 14.4 0.3 0.034 13.7 0.2 1.3 1 0 0 1 1 1 0 Sodium/calcium exchanger protein Pex24p PF06398.6 EIW72433.1 - 0.29 9.9 1.0 0.42 9.3 0.7 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Ank_2 PF12796.2 EIW72434.1 - 1.1e-20 73.7 0.0 2.3e-14 53.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIW72434.1 - 8.1e-18 64.0 5.6 3.3e-08 33.4 0.2 3.9 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW72434.1 - 1.6e-17 63.4 2.4 2.1e-12 47.2 0.1 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EIW72434.1 - 2.8e-17 61.5 2.9 5.3e-07 29.1 0.2 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EIW72434.1 - 1.2e-12 46.7 1.1 5.5e-05 23.0 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat eIF-1a PF01176.14 EIW72436.1 - 0.0031 16.8 0.1 0.013 14.8 0.0 1.8 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 Calici_coat PF00915.15 EIW72436.1 - 0.12 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Calicivirus coat protein Glyco_hydro_3 PF00933.16 EIW72437.1 - 2.7e-91 305.6 0.0 3.7e-91 305.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW72437.1 - 7.2e-62 208.8 0.2 2e-60 204.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW72437.1 - 2.5e-22 78.5 0.2 5e-22 77.6 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain APG6 PF04111.7 EIW72438.1 - 8.5e-62 208.9 0.0 1.2e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 NPL4 PF05021.10 EIW72439.1 - 7.8e-97 324.1 0.0 9.9e-97 323.7 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EIW72439.1 - 2.2e-61 205.8 0.1 3.3e-61 205.2 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region zf-RanBP PF00641.13 EIW72439.1 - 0.0052 15.8 0.3 0.0052 15.8 0.2 2.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others UN_NPL4 PF11543.3 EIW72439.1 - 0.041 14.1 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 GCC2_GCC3 PF07699.8 EIW72439.1 - 5.8 6.5 8.6 6.8 6.3 1.0 3.4 3 0 0 3 3 3 0 GCC2 and GCC3 Cir_N PF10197.4 EIW72440.1 - 0.012 15.6 1.3 0.012 15.6 0.9 4.1 4 0 0 4 4 4 0 N-terminal domain of CBF1 interacting co-repressor CIR AA_permease_N PF08403.5 EIW72440.1 - 0.036 13.3 0.1 0.13 11.6 0.0 2.0 1 0 0 1 1 1 0 Amino acid permease N-terminal MIP PF00230.15 EIW72441.1 - 8.3e-46 156.2 18.8 1e-45 155.9 13.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2628 PF10947.3 EIW72441.1 - 1.7 8.4 9.8 1.8 8.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) UBN2_2 PF14227.1 EIW72444.1 - 1.8e-06 27.5 0.1 3e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW72444.1 - 1.1e-05 25.1 0.1 0.00016 21.4 0.0 2.1 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF664 PF04978.7 EIW72444.1 - 0.072 13.3 0.1 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF664) DDE_1 PF03184.14 EIW72445.1 - 1.4e-07 30.9 0.0 3e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease CAF-1_p150 PF11600.3 EIW72445.1 - 0.2 10.9 30.7 0.52 9.6 21.3 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GAGA_bind PF06217.7 EIW72445.1 - 0.59 10.0 7.1 1 9.2 4.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3818 PF12825.2 EIW72445.1 - 6.3 5.3 6.2 9.7 4.7 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) rve PF00665.21 EIW72448.1 - 6.9e-19 68.1 0.0 1.3e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIW72448.1 - 2e-08 33.7 0.4 4.1e-08 32.7 0.1 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIW72448.1 - 0.04 13.3 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger rve_3 PF13683.1 EIW72448.1 - 0.14 11.6 1.0 0.45 10.0 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain Glyco_transf_22 PF03901.12 EIW72451.1 - 1.9e-32 112.8 17.7 2.6e-32 112.3 12.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PQ-loop PF04193.9 EIW72452.1 - 7.5e-36 121.4 7.1 1.6e-17 62.8 0.3 2.8 2 0 0 2 2 2 2 PQ loop repeat PX PF00787.19 EIW72453.1 - 1e-20 73.5 0.0 2.3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 PX domain FAM92 PF06730.6 EIW72453.1 - 0.011 15.0 0.1 0.026 13.8 0.1 1.5 1 0 0 1 1 1 0 FAM92 protein DUF2924 PF11149.3 EIW72453.1 - 0.094 12.7 1.2 0.35 10.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) Cep57_MT_bd PF06657.8 EIW72454.1 - 2.8e-20 72.0 0.0 2.8e-20 72.0 0.0 4.2 4 1 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Reo_sigmaC PF04582.7 EIW72454.1 - 0.0018 17.5 1.2 0.0042 16.3 0.8 1.5 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Surfac_D-trimer PF09006.6 EIW72454.1 - 0.061 13.0 0.4 0.36 10.5 0.0 2.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation AAA_13 PF13166.1 EIW72454.1 - 0.14 10.6 12.5 0.066 11.6 7.1 1.6 2 0 0 2 2 2 0 AAA domain LPP PF04728.8 EIW72454.1 - 0.2 11.5 2.6 4.6 7.1 0.1 3.5 3 1 1 4 4 4 0 Lipoprotein leucine-zipper DUF4279 PF14106.1 EIW72454.1 - 0.21 11.4 1.6 3.4 7.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) Prominin PF05478.6 EIW72454.1 - 0.33 8.4 1.4 0.48 7.8 1.0 1.2 1 0 0 1 1 1 0 Prominin Atg14 PF10186.4 EIW72454.1 - 0.77 8.6 24.4 0.77 8.6 4.3 2.9 2 1 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 EIW72454.1 - 1.4 8.8 15.4 3.1 7.7 0.1 5.2 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EIW72454.1 - 3.5 7.7 9.7 0.24 11.5 1.7 2.7 2 1 2 4 4 3 0 Fibrinogen alpha/beta chain family HeLo PF14479.1 EIW72454.1 - 6.9 6.3 13.4 0.053 13.2 1.5 2.9 2 1 1 3 3 3 0 Prion-inhibition and propagation DUF4404 PF14357.1 EIW72454.1 - 7.7 7.0 24.8 1.3 9.5 0.5 5.1 4 1 1 5 5 5 0 Domain of unknown function (DUF4404) Glucosamine_iso PF01182.15 EIW72455.1 - 9.2e-23 81.0 0.0 1.7e-22 80.1 0.0 1.4 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.8 EIW72455.1 - 0.043 12.7 0.2 0.086 11.7 0.0 1.5 2 0 0 2 2 2 0 Putative sugar-binding domain CTDII PF01556.13 EIW72456.1 - 5.4e-26 90.3 0.1 4.1e-17 61.8 0.0 3.8 4 0 0 4 4 4 2 DnaJ C terminal domain DnaJ PF00226.26 EIW72456.1 - 1.4e-23 82.4 1.1 2.1e-23 81.8 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EIW72456.1 - 1.6e-09 37.7 21.2 1.6e-09 37.7 14.7 2.1 3 0 0 3 3 3 1 DnaJ central domain Cytochrome_C7 PF14522.1 EIW72456.1 - 0.017 14.7 12.3 0.021 14.4 3.4 2.4 1 1 1 2 2 2 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 EIW72456.1 - 0.081 13.2 9.7 0.22 11.8 6.7 1.8 1 1 0 1 1 1 0 Cytochrome c3 Cytochrom_CIII PF02085.11 EIW72456.1 - 0.1 12.7 4.4 0.23 11.5 3.1 1.6 1 0 0 1 1 1 0 Class III cytochrome C family HypA PF01155.14 EIW72456.1 - 0.85 9.3 9.4 1.9 8.1 0.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Amidohydro_4 PF13147.1 EIW72457.1 - 4.7e-10 39.9 0.1 1.7e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EIW72457.1 - 0.00024 20.9 0.0 0.68 9.5 0.0 2.5 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EIW72457.1 - 0.0012 18.6 0.0 0.0029 17.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase PCI PF01399.22 EIW72458.1 - 0.0083 16.4 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 PCI domain HA2 PF04408.18 EIW72461.1 - 4.8e-20 71.4 0.1 5.6e-19 68.0 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIW72461.1 - 4.1e-18 65.2 0.0 9.5e-18 64.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIW72461.1 - 6.9e-13 48.2 0.0 2.2e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW72461.1 - 1.4e-09 37.7 0.1 3.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EIW72461.1 - 0.00078 18.4 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 EIW72461.1 - 0.00089 18.7 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIW72461.1 - 0.0012 18.9 0.0 0.0058 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW72461.1 - 0.017 14.8 0.1 0.054 13.2 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain FAD_binding_3 PF01494.14 EIW72462.1 - 5.1e-18 65.2 0.0 2.8e-17 62.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW72462.1 - 1.2e-05 25.2 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW72462.1 - 0.00018 20.5 0.0 0.00042 19.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 EIW72462.1 - 0.0018 17.1 0.0 0.19 10.5 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_3 PF13738.1 EIW72462.1 - 0.0027 17.8 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW72462.1 - 0.0081 16.5 0.0 0.12 12.8 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIW72462.1 - 0.016 13.8 0.0 1 7.8 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.11 EIW72462.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EIW72462.1 - 0.08 11.4 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein EF1_GNE PF00736.14 EIW72463.1 - 4.2e-31 106.4 3.0 7.5e-31 105.6 2.1 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EIW72463.1 - 6.2e-11 42.2 7.3 6.2e-11 42.2 5.1 3.1 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EIW72463.1 - 8.6e-05 22.9 0.4 0.00029 21.2 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW72463.1 - 0.0046 16.9 2.5 0.0076 16.2 0.0 2.6 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW72463.1 - 0.006 16.4 0.4 0.036 13.9 0.3 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.7 EIW72463.1 - 0.089 12.4 5.8 0.14 11.8 4.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3752 PF12572.3 EIW72463.1 - 0.19 11.8 6.5 0.32 11.1 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) FlaC_arch PF05377.6 EIW72463.1 - 0.23 11.3 3.1 0.27 11.1 0.5 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) eIF3_subunit PF08597.5 EIW72463.1 - 0.32 10.5 14.1 0.48 9.9 9.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Fungal_trans PF04082.13 EIW72477.1 - 2.9e-21 75.5 0.4 1.2e-20 73.4 0.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW72477.1 - 4e-08 33.0 8.5 8.4e-08 32.0 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ApbA PF02558.11 EIW72478.1 - 2.4e-19 69.2 0.0 3.4e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EIW72478.1 - 3.7e-19 68.9 0.0 5.4e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ox_reductase_C PF08635.5 EIW72480.1 - 1.3e-57 193.1 0.0 2.2e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EIW72480.1 - 5.3e-13 49.5 0.2 1.4e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GN3L_Grn1 PF08701.6 EIW72481.1 - 1.5e-20 72.8 15.8 3.5e-20 71.6 10.9 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EIW72481.1 - 8.9e-11 41.7 0.1 2.7e-07 30.5 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW72481.1 - 1.8e-06 27.3 0.4 0.11 11.7 0.0 3.4 3 1 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 EIW72481.1 - 1.3e-05 24.6 0.0 0.017 14.5 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EIW72481.1 - 0.0016 17.5 0.0 0.0034 16.5 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EIW72481.1 - 0.0025 18.2 0.0 0.016 15.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EIW72481.1 - 0.037 13.8 7.8 2.2 8.0 0.3 3.7 3 1 0 3 3 3 0 Dynamin family SRPRB PF09439.5 EIW72481.1 - 0.038 13.2 0.0 0.078 12.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EIW72481.1 - 0.048 12.8 0.0 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 EIW72481.1 - 0.07 12.1 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Septin cobW PF02492.14 EIW72481.1 - 0.08 12.3 0.3 6 6.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NOA36 PF06524.7 EIW72481.1 - 7.6 5.6 18.0 0.37 10.0 7.6 2.2 2 0 0 2 2 2 0 NOA36 protein LRR_4 PF12799.2 EIW72482.1 - 2.2e-35 119.7 42.6 4.9e-08 32.4 0.6 8.8 6 1 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW72482.1 - 2.9e-22 78.1 41.0 3.2e-05 23.5 1.4 7.7 5 1 5 10 10 10 7 Leucine rich repeat LRR_1 PF00560.28 EIW72482.1 - 7e-11 40.6 44.2 2.7 8.3 0.2 12.5 11 1 1 12 12 12 7 Leucine Rich Repeat LRR_7 PF13504.1 EIW72482.1 - 7.7e-10 37.3 33.0 5.9 7.5 0.0 11.9 11 0 0 11 11 11 3 Leucine rich repeat LRR_6 PF13516.1 EIW72482.1 - 3.4e-06 26.5 40.6 2.6 8.3 0.1 11.9 9 2 3 12 12 12 3 Leucine Rich repeat LRR_9 PF14580.1 EIW72482.1 - 2.6e-05 23.8 8.8 0.12 11.9 1.7 4.5 2 1 3 5 5 5 2 Leucine-rich repeat PXA PF02194.10 EIW72483.1 - 3.5e-35 121.2 0.1 3.5e-35 121.2 0.1 2.5 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EIW72483.1 - 3.3e-25 88.3 0.1 2.4e-24 85.5 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EIW72483.1 - 5.2e-16 58.4 0.0 1.6e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EIW72483.1 - 1.1e-11 44.8 0.0 2.7e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_M50B PF13398.1 EIW72483.1 - 1.7e-07 30.8 15.9 4e-05 23.0 0.5 3.2 3 0 0 3 3 3 2 Peptidase M50B-like ResB PF05140.9 EIW72483.1 - 0.044 12.3 0.1 0.083 11.4 0.1 1.3 1 0 0 1 1 1 0 ResB-like family GATA PF00320.22 EIW72484.1 - 0.00011 21.4 2.3 0.00025 20.3 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger RTA1 PF04479.8 EIW72485.1 - 4.7e-33 114.5 7.1 6.1e-33 114.2 4.9 1.1 1 0 0 1 1 1 1 RTA1 like protein AAA PF00004.24 EIW72487.1 - 5.4e-41 139.8 0.0 1.9e-40 138.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW72487.1 - 1.9e-05 24.7 0.1 0.0017 18.3 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EIW72487.1 - 0.00013 21.1 0.0 0.00084 18.4 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIW72487.1 - 0.00035 20.7 0.5 0.022 14.9 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW72487.1 - 0.00065 19.4 0.1 0.0038 16.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIW72487.1 - 0.0021 18.0 0.0 0.021 14.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EIW72487.1 - 0.004 16.4 0.1 0.036 13.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EIW72487.1 - 0.0059 15.7 0.1 0.029 13.5 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EIW72487.1 - 0.007 15.7 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EIW72487.1 - 0.0094 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW72487.1 - 0.011 15.5 0.3 0.026 14.2 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EIW72487.1 - 0.012 16.4 0.2 0.036 14.8 0.1 2.0 2 1 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EIW72487.1 - 0.027 14.3 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW72487.1 - 0.028 13.3 0.0 0.058 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EIW72487.1 - 0.047 13.8 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 EIW72487.1 - 0.057 12.8 4.3 0.32 10.3 0.1 2.8 2 1 0 3 3 3 0 AAA domain SAS4 PF15460.1 EIW72487.1 - 0.14 12.0 2.4 0.36 10.7 1.7 1.7 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 AAA_24 PF13479.1 EIW72487.1 - 0.18 11.3 1.7 0.25 10.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain MS_channel PF00924.13 EIW72488.1 - 3.7e-22 78.6 1.8 3.7e-22 78.6 1.2 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel ERbeta_N PF12497.3 EIW72488.1 - 0.013 15.3 1.8 0.034 13.9 1.3 1.6 1 0 0 1 1 1 0 Estrogen receptor beta EF-hand_1 PF00036.27 EIW72488.1 - 0.029 13.6 0.2 0.068 12.5 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EIW72488.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain RasGEF PF00617.14 EIW72489.1 - 3.8e-51 173.4 0.0 6.8e-51 172.6 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIW72489.1 - 8.4e-21 74.0 0.0 2.4e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.12 EIW72489.1 - 8.6e-07 28.3 0.0 1.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIW72489.1 - 2.5e-06 26.9 0.0 5.8e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW72489.1 - 0.00021 20.6 0.1 0.0005 19.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain Fungal_trans PF04082.13 EIW72490.1 - 1.6e-08 33.7 0.2 3e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW72490.1 - 1.6e-06 27.8 12.2 3.6e-06 26.7 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP90 PF00183.13 EIW72491.1 - 2.2e-243 808.5 26.4 2.6e-243 808.2 18.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EIW72491.1 - 9.5e-12 44.6 0.0 1.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIW72491.1 - 2.7e-11 43.2 0.2 2.7e-11 43.2 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UDPGT PF00201.13 EIW72491.1 - 0.34 9.3 2.9 0.29 9.6 0.3 1.9 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase DUF221 PF02714.10 EIW72492.1 - 1.6e-38 132.3 16.4 1.6e-38 132.3 11.3 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIW72492.1 - 1.5e-16 60.3 1.8 1.5e-16 60.3 1.2 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.17 EIW72492.1 - 0.018 14.6 0.0 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW72492.1 - 0.031 14.2 0.0 4 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4463 PF14703.1 EIW72492.1 - 0.046 14.2 0.0 0.15 12.6 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) Pet127 PF08634.5 EIW72493.1 - 7.3e-102 340.1 0.2 1.1e-101 339.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 DUF605 PF04652.11 EIW72493.1 - 6.2 6.1 20.2 11 5.3 14.0 1.3 1 0 0 1 1 1 0 Vta1 like TCTP PF00838.12 EIW72494.1 - 1.8e-67 226.4 1.6 2.1e-67 226.2 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein GerPC PF10737.4 EIW72494.1 - 0.052 13.3 0.2 0.079 12.7 0.1 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC V-SNARE PF05008.10 EIW72494.1 - 0.11 12.6 0.4 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus 2OG-FeII_Oxy_2 PF13532.1 EIW72495.1 - 2.7e-37 128.5 0.0 1.2e-35 123.1 0.0 2.1 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Mito_carr PF00153.22 EIW72497.1 - 1.7e-66 219.9 2.0 4.9e-23 80.6 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EIW72497.1 - 1.1e-17 61.8 7.0 6.1e-06 25.1 0.2 5.5 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EIW72497.1 - 1.2e-15 57.4 5.6 3.7e-08 33.3 0.8 4.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 EIW72497.1 - 1.4e-15 55.6 6.5 7.3e-06 25.4 0.1 5.4 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.1 EIW72497.1 - 1.6e-11 43.6 6.7 0.0021 17.6 0.3 4.7 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EIW72497.1 - 1.1e-09 37.1 6.6 0.00029 20.0 0.3 4.3 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 EIW72497.1 - 0.004 16.8 0.8 14 5.5 0.0 3.5 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Bac_rhodopsin PF01036.13 EIW72498.1 - 4.6e-51 173.2 18.7 5.9e-51 172.9 13.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Fungal_trans PF04082.13 EIW72499.1 - 2.4e-11 43.0 1.2 4.2e-11 42.2 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TIM-br_sig_trns PF09370.5 EIW72499.1 - 0.15 11.0 0.0 4.4 6.2 0.0 2.1 2 0 0 2 2 2 0 TIM-barrel signal transduction protein MR_MLE_C PF13378.1 EIW72500.1 - 6.3e-15 55.1 0.0 1.6e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EIW72500.1 - 2.5e-12 47.1 0.1 9e-12 45.3 0.0 2.0 3 0 0 3 3 3 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EIW72500.1 - 6.8e-09 35.7 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EIW72500.1 - 0.0075 15.2 0.0 0.018 14.0 0.0 1.6 1 1 1 2 2 2 1 Methylaspartate ammonia-lyase C-terminus TauD PF02668.11 EIW72501.1 - 2.5e-52 178.1 0.1 2.9e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RE_AlwI PF09491.5 EIW72501.1 - 0.04 12.3 0.0 0.055 11.9 0.0 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease Sugar_tr PF00083.19 EIW72502.1 - 9.9e-80 268.2 18.2 1.2e-79 268.0 12.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW72502.1 - 8.8e-20 70.7 33.2 3.9e-16 58.6 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EIW72502.1 - 7.5e-05 21.0 0.1 0.00013 20.3 0.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector ABC2_membrane_2 PF12679.2 EIW72502.1 - 0.0032 16.3 7.5 0.0081 15.0 5.2 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein Pkinase PF00069.20 EIW72503.1 - 5.7e-65 219.0 0.0 6.6e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72503.1 - 1.8e-43 148.4 0.0 2.1e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW72503.1 - 4.7e-09 35.6 0.0 1.6e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIW72503.1 - 6.4e-05 22.1 0.0 0.0001 21.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW72503.1 - 0.0094 15.7 0.1 0.24 11.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family SR-25 PF10500.4 EIW72504.1 - 0.12 11.8 5.3 0.17 11.3 3.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TGS PF02824.16 EIW72505.1 - 4e-24 84.1 0.0 8.6e-24 83.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EIW72505.1 - 5.3e-17 61.8 0.1 1.1e-16 60.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW72505.1 - 5e-10 38.8 0.1 1.6e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 EIW72505.1 - 0.0044 15.8 0.2 0.0097 14.7 0.2 1.6 1 0 0 1 1 1 1 ArgK protein GTP_EFTU PF00009.22 EIW72505.1 - 0.017 14.5 0.1 4.1 6.7 0.0 3.1 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EIW72505.1 - 0.024 14.4 0.4 3 7.6 0.0 2.6 1 1 1 2 2 2 0 Dynamin family RF-1 PF00472.15 EIW72506.1 - 1.1e-15 57.4 0.3 1.7e-15 56.7 0.2 1.2 1 0 0 1 1 1 1 RF-1 domain dUTPase PF00692.14 EIW72507.1 - 6.3e-38 129.1 0.0 7.5e-38 128.8 0.0 1.1 1 0 0 1 1 1 1 dUTPase Pol_alpha_B_N PF08418.5 EIW72508.1 - 7.2e-54 182.9 0.2 2.9e-53 181.0 0.1 1.8 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EIW72508.1 - 3.5e-33 114.6 0.1 6e-33 113.8 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Mito_carr PF00153.22 EIW72509.1 - 2e-14 53.0 0.0 1.1e-07 31.4 0.0 3.0 2 1 0 2 2 2 2 Mitochondrial carrier protein 2-Hacid_dh_C PF02826.14 EIW72510.1 - 2.8e-38 130.8 0.0 4.3e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW72510.1 - 1.2e-23 82.9 0.0 1.4e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 EIW72510.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Zn_clus PF00172.13 EIW72511.1 - 0.00038 20.3 7.1 0.0006 19.6 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 EIW72512.1 - 6.2e-10 39.6 0.1 4.1e-09 36.9 0.0 2.4 2 1 0 2 2 2 1 SET domain TFIIA PF03153.8 EIW72512.1 - 0.0019 18.1 4.7 0.0028 17.6 3.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EBV-NA3 PF05009.7 EIW72512.1 - 0.25 10.5 5.5 0.51 9.5 3.8 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Nucleoplasmin PF03066.10 EIW72512.1 - 0.52 9.8 10.3 1.2 8.6 6.9 1.8 2 0 0 2 2 2 0 Nucleoplasmin Mak16 PF04874.9 EIW72512.1 - 4.9 7.2 15.6 1.2 9.3 8.2 1.9 2 0 0 2 2 2 0 Mak16 protein C-terminal region RXT2_N PF08595.6 EIW72512.1 - 9.5 6.0 7.3 21 4.9 5.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal TPR_11 PF13414.1 EIW72513.1 - 6.5e-06 25.7 0.3 1.5e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 TPR repeat Rhomboid_SP PF12595.3 EIW72513.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 Rhomboid serine protease SET PF00856.23 EIW72513.1 - 0.042 14.1 0.0 4.3 7.6 0.0 3.0 3 0 0 3 3 3 0 SET domain SLAC1 PF03595.12 EIW72514.1 - 2.9e-77 259.5 48.1 3.2e-77 259.3 33.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3154 PF11351.3 EIW72514.1 - 0.074 12.7 1.2 0.23 11.2 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) DUF4227 PF14004.1 EIW72515.1 - 0.16 11.8 1.8 0.17 11.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4227) 6PGD PF00393.14 EIW72516.1 - 7.7e-55 186.1 0.0 1.7e-54 185.0 0.0 1.5 2 0 0 2 2 2 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EIW72516.1 - 1.7e-36 125.5 0.0 3.3e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EIW72516.1 - 3e-06 27.0 0.0 7.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EIW72516.1 - 0.00019 21.7 4.1 0.00029 21.1 0.2 3.1 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EIW72516.1 - 0.00047 19.9 0.0 0.0013 18.4 0.0 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EIW72516.1 - 0.0013 18.1 0.1 0.0049 16.2 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EIW72516.1 - 0.016 14.6 0.1 0.05 13.0 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.1 EIW72516.1 - 0.073 13.1 0.1 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Alpha-amylase PF00128.19 EIW72517.1 - 1.1e-93 314.1 0.0 1.8e-93 313.3 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EIW72517.1 - 0.00067 18.6 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Tetraspannin PF00335.15 EIW72518.1 - 1e-05 24.9 0.8 1.7e-05 24.2 0.6 1.3 1 0 0 1 1 1 1 Tetraspanin family BIV_Env PF05858.7 EIW72518.1 - 1.5 6.7 5.4 0.32 8.9 1.5 1.4 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) His_Phos_2 PF00328.17 EIW72519.1 - 2e-34 119.4 0.0 1e-33 117.1 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ras PF00071.17 EIW72520.1 - 2.7e-57 192.6 0.1 3.1e-57 192.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EIW72520.1 - 1.1e-16 60.5 0.1 1.5e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EIW72520.1 - 3.5e-16 59.7 0.0 4.6e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW72520.1 - 1.2e-06 28.4 0.0 1.4e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EIW72520.1 - 4.6e-05 22.6 0.0 6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIW72520.1 - 4.7e-05 22.6 0.1 7.6e-05 22.0 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EIW72520.1 - 7.8e-05 22.1 0.0 0.00038 19.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EIW72520.1 - 0.0012 18.1 0.0 0.24 10.6 0.0 2.3 2 1 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 EIW72520.1 - 0.0089 15.8 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Dynamin family Septin PF00735.13 EIW72520.1 - 0.023 13.7 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.1 EIW72520.1 - 0.031 14.2 0.1 0.13 12.1 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EIW72520.1 - 0.048 12.8 0.2 0.21 10.7 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 G-alpha PF00503.15 EIW72520.1 - 0.059 12.0 1.6 2.6 6.6 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 EIW72520.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sulf_transp PF04143.9 EIW72521.1 - 2e-16 59.7 16.1 3.5e-11 42.9 5.0 4.1 5 0 0 5 5 5 2 Sulphur transport DUF4341 PF14241.1 EIW72521.1 - 2.1e-15 56.1 7.9 2.1e-15 56.1 5.5 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4341) Glyco_hydro_92 PF07971.7 EIW72522.1 - 3.3e-150 501.0 0.1 4.3e-150 500.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 MFS_1 PF07690.11 EIW72523.1 - 2e-25 89.2 78.3 1.7e-23 82.8 39.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 EIW72524.1 - 2.8e-12 47.1 0.0 4.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW72524.1 - 1.8e-08 33.6 0.0 1.8e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EIW72524.1 - 2.5e-06 25.9 0.0 4.9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIW72524.1 - 0.0028 17.5 0.0 2.6 7.8 0.0 3.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EIW72524.1 - 0.0063 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EIW72524.1 - 0.036 14.3 0.1 0.74 10.1 0.0 2.3 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EIW72524.1 - 0.068 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EIW72524.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ILVD_EDD PF00920.16 EIW72525.1 - 3.2e-150 501.0 0.0 3.7e-150 500.8 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family DIOX_N PF14226.1 EIW72526.1 - 7.4e-23 81.3 0.1 1.5e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW72526.1 - 5.2e-21 74.7 0.0 8.2e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LETM1 PF07766.8 EIW72527.1 - 5e-98 327.3 0.7 5e-98 327.3 0.5 2.0 3 0 0 3 3 3 1 LETM1-like protein SAP PF02037.22 EIW72527.1 - 0.00057 19.3 0.0 0.3 10.6 0.0 2.8 2 0 0 2 2 2 2 SAP domain EF-hand_7 PF13499.1 EIW72527.1 - 0.044 13.9 0.0 0.7 10.0 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.27 EIW72527.1 - 0.26 10.6 1.1 7.8 6.0 0.1 3.4 4 0 0 4 4 4 0 EF hand Cyt-b5 PF00173.23 EIW72528.1 - 4e-06 26.5 0.0 2.4e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF948 PF06103.6 EIW72529.1 - 0.028 14.2 2.8 0.038 13.8 1.6 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Parvo_coat PF00740.13 EIW72529.1 - 0.03 13.2 2.5 0.038 12.9 1.7 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF3584 PF12128.3 EIW72529.1 - 0.88 6.8 16.5 1.1 6.4 11.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spond_N PF06468.8 EIW72529.1 - 1.4 8.5 5.9 1.6 8.3 3.7 1.4 1 1 0 1 1 1 0 Spondin_N APG6 PF04111.7 EIW72529.1 - 1.5 7.7 14.7 2.1 7.3 10.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2894 PF11445.3 EIW72529.1 - 6.2 7.0 13.1 8.5 6.5 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) HSP70 PF00012.15 EIW72529.1 - 6.9 4.4 13.8 8.5 4.1 9.6 1.0 1 0 0 1 1 1 0 Hsp70 protein TIL PF01826.12 EIW72530.1 - 0.0058 16.7 1.6 0.017 15.2 1.1 1.8 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain SLR1-BP PF07333.7 EIW72530.1 - 0.02 15.1 1.5 0.041 14.1 1.0 1.5 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Mito_carr PF00153.22 EIW72531.1 - 3.3e-57 190.1 3.5 1.1e-19 69.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1604 PF07713.8 EIW72531.1 - 0.11 12.2 0.3 0.33 10.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) HTH_24 PF13412.1 EIW72533.1 - 0.063 12.6 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MFS_1 PF07690.11 EIW72535.1 - 8e-37 126.7 45.5 2.3e-36 125.2 30.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2140 PF09911.4 EIW72535.1 - 0.021 13.9 0.1 0.062 12.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Ferritin_2 PF13668.1 EIW72536.1 - 2.6e-18 66.3 0.1 2.3e-17 63.2 0.1 2.3 2 1 0 2 2 2 1 Ferritin-like domain Cas_Cas1 PF01867.11 EIW72538.1 - 0.04 12.9 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas1 SNARE PF05739.14 EIW72540.1 - 3.3e-05 23.4 2.2 3.3e-05 23.4 1.5 2.4 3 0 0 3 3 3 1 SNARE domain V-SNARE_C PF12352.3 EIW72540.1 - 0.64 10.1 7.0 6.5 6.9 0.3 3.0 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DRY_EERY PF09750.4 EIW72540.1 - 1 9.4 6.2 0.14 12.3 1.1 2.0 2 1 0 2 2 2 0 Alternative splicing regulator DUF506 PF04720.7 EIW72540.1 - 1.6 8.3 10.3 0.16 11.5 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF506) DUF3035 PF11233.3 EIW72540.1 - 7.1 6.6 11.2 14 5.6 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3035) DUF2414 PF10309.4 EIW72541.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) RTA1 PF04479.8 EIW72542.1 - 7.1e-17 61.6 9.4 1.1e-16 61.0 6.5 1.2 1 0 0 1 1 1 1 RTA1 like protein 7TM_GPCR_Srh PF10318.4 EIW72542.1 - 2.8 6.6 10.8 0.016 14.0 0.7 2.1 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srh PAS_3 PF08447.6 EIW72543.1 - 2.6e-12 46.6 0.0 3e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 EIW72543.1 - 1.4e-06 28.0 0.0 4.5e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EIW72543.1 - 5.8e-05 23.4 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.1 EIW72543.1 - 0.00014 21.8 0.0 0.00077 19.3 0.0 2.1 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.5 EIW72543.1 - 0.0071 16.3 0.0 0.27 11.2 0.0 2.5 2 1 0 2 2 2 1 PAS fold Flavodoxin_5 PF12724.2 EIW72543.1 - 0.15 12.0 0.0 0.65 9.9 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain HA2 PF04408.18 EIW72544.1 - 8.6e-18 64.2 0.4 4e-16 58.8 0.0 3.2 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIW72544.1 - 3.1e-13 49.3 0.0 6.3e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 EIW72544.1 - 1.3e-09 38.4 0.1 0.0017 18.8 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.24 EIW72544.1 - 5.7e-08 32.4 0.2 1.3e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EIW72544.1 - 2.8e-06 27.1 0.0 8.5e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.1 EIW72544.1 - 0.016 14.9 0.0 0.067 12.9 0.0 2.2 1 1 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EIW72544.1 - 0.067 13.0 0.0 0.42 10.4 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW72544.1 - 0.078 13.1 0.1 0.3 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain zf-CHCC PF10276.4 EIW72545.1 - 9.2e-18 63.8 1.6 1.3e-17 63.2 1.1 1.3 1 0 0 1 1 1 1 Zinc-finger domain B12D PF06522.6 EIW72546.1 - 0.00031 20.3 0.2 0.00058 19.5 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Phage_Gp23 PF10669.4 EIW72547.1 - 0.18 11.9 1.9 1.5 8.9 0.1 2.5 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Sec62 PF03839.11 EIW72548.1 - 9.8e-44 149.4 10.3 1.4e-42 145.6 7.1 2.0 1 1 0 1 1 1 1 Translocation protein Sec62 Esterase PF00756.15 EIW72549.1 - 8.6e-47 159.6 0.0 1.1e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EIW72549.1 - 1.8e-06 27.7 0.0 3.4e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW72549.1 - 0.00096 19.0 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIW72549.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 EIW72549.1 - 0.014 14.3 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EIW72549.1 - 0.05 12.8 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family OTU PF02338.14 EIW72551.1 - 4.6e-16 59.4 0.0 1.1e-15 58.2 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EIW72551.1 - 0.0018 17.6 0.0 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase C65 Otubain ACBP PF00887.14 EIW72552.1 - 5.6e-29 99.6 0.1 7.3e-29 99.2 0.1 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Ribosomal_L12 PF00542.14 EIW72552.1 - 0.19 11.7 2.7 0.3 11.1 1.9 1.3 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain HEAT PF02985.17 EIW72553.1 - 3e-41 135.7 29.7 0.00048 19.9 0.0 13.9 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EIW72553.1 - 5.9e-33 113.0 16.5 2.2e-07 31.0 0.0 7.4 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 EIW72553.1 - 2.3e-17 62.9 21.9 0.0056 17.1 0.1 9.1 8 2 2 10 10 10 6 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIW72553.1 - 7.7e-11 42.2 2.8 0.0025 18.1 0.0 6.9 3 1 7 10 10 10 3 Vacuolar 14 Fab1-binding region Arm PF00514.18 EIW72553.1 - 1.2e-09 37.5 5.2 0.91 9.4 0.0 8.1 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EIW72553.1 - 7.8e-06 24.4 2.8 0.0074 14.6 1.7 3.9 2 1 0 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.3 EIW72553.1 - 0.0028 17.0 0.3 16 4.7 0.0 4.6 4 1 0 4 4 4 1 CLASP N terminal HEAT_PBS PF03130.11 EIW72553.1 - 0.0056 17.0 3.4 1.1 9.9 0.0 5.6 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Cohesin_HEAT PF12765.2 EIW72553.1 - 1.6 8.7 12.3 3.1 7.8 0.1 5.1 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion HSP70 PF00012.15 EIW72554.1 - 6.4e-163 542.8 0.3 6.4e-163 542.8 0.2 2.1 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EIW72554.1 - 1.4e-10 40.3 0.0 3.3e-10 39.0 0.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.17 EIW72554.1 - 0.042 13.6 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain AbiH PF14253.1 EIW72554.1 - 0.14 11.7 3.1 0.3 10.6 2.2 1.5 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DPBB_1 PF03330.13 EIW72556.1 - 2.8e-08 33.6 0.0 4.3e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW72556.1 - 0.016 14.8 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Barwin family PIG-L PF02585.12 EIW72557.1 - 3.3e-23 82.5 0.0 5.8e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase EI24 PF07264.6 EIW72559.1 - 0.006 16.0 5.9 0.012 15.0 4.1 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Nucleoporin_FG PF13634.1 EIW72561.1 - 2.8 8.1 6.8 0.89 9.8 2.3 1.9 2 1 0 2 2 2 0 Nucleoporin FG repeat region AT_hook PF02178.14 EIW72562.1 - 0.11 12.2 7.0 0.2 11.4 4.9 1.5 1 0 0 1 1 1 0 AT hook motif MFS_1 PF07690.11 EIW72563.1 - 1.4e-12 47.0 42.0 1.4e-12 47.0 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EIW72563.1 - 1.5e-11 44.0 5.7 1.5e-11 44.0 4.0 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MliC PF09864.4 EIW72564.1 - 0.032 13.9 0.6 0.041 13.6 0.4 1.3 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Pkinase PF00069.20 EIW72565.1 - 3e-41 141.2 0.0 3.5e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72565.1 - 6.4e-20 71.2 0.0 7.5e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EIW72565.1 - 0.025 13.3 0.2 0.037 12.8 0.2 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EIW72565.1 - 0.033 13.1 0.0 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like BcrAD_BadFG PF01869.15 EIW72566.1 - 0.00074 18.8 0.0 0.11 11.7 0.0 2.8 3 1 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family Zn_clus PF00172.13 EIW72567.1 - 0.00014 21.6 9.4 0.00024 20.9 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 EIW72569.1 - 1.9e-34 118.5 0.4 5.5e-34 117.0 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW72569.1 - 2.9e-22 78.3 0.0 6.3e-12 45.1 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EIW72569.1 - 0.00023 21.0 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW72569.1 - 0.03 14.4 0.1 0.11 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain Zn_clus PF00172.13 EIW72570.1 - 1.2e-06 28.3 10.2 2.7e-06 27.1 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIW72570.1 - 0.0011 17.8 0.0 0.0046 15.8 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW72571.1 - 0.00024 20.9 7.8 0.00079 19.2 5.4 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF260 PF03195.9 EIW72571.1 - 0.22 11.7 1.5 2 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF260 ThiF PF00899.16 EIW72572.1 - 7.9e-07 28.9 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EIW72572.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 MoeZ/MoeB domain Suc_Fer-like PF06999.7 EIW72573.1 - 7.2e-27 94.8 0.0 1e-26 94.3 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like E3_binding PF02817.12 EIW72573.1 - 0.14 11.7 1.4 20 4.9 0.0 3.2 3 0 0 3 3 3 0 e3 binding domain DUF3636 PF12331.3 EIW72574.1 - 0.0065 16.0 0.1 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Ras PF00071.17 EIW72575.1 - 1.8e-57 193.2 0.0 2.2e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW72575.1 - 4.3e-19 69.1 0.0 7.2e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW72575.1 - 1.8e-15 56.6 0.0 2.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW72575.1 - 1.5e-07 30.7 0.0 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW72575.1 - 4.7e-05 22.9 0.0 0.00011 21.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW72575.1 - 7.9e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EIW72575.1 - 0.03 14.3 0.0 0.048 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain API5 PF05918.6 EIW72576.1 - 0.76 8.2 11.3 1.2 7.4 7.9 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-Sec23_Sec24 PF04810.10 EIW72577.1 - 0.1 12.1 0.6 0.18 11.3 0.4 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Asp PF00026.18 EIW72578.1 - 4.7e-18 65.4 0.1 1.3e-17 64.0 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW72578.1 - 0.0025 17.7 0.3 0.0048 16.8 0.2 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Phage_T4_Gp30_7 PF06919.6 EIW72578.1 - 0.24 11.4 0.0 0.47 10.4 0.0 1.4 1 0 0 1 1 1 0 Phage Gp30.7 protein YqzH PF14164.1 EIW72580.1 - 0.084 12.7 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 YqzH-like protein DUF2587 PF10759.4 EIW72582.1 - 0.021 14.2 0.1 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW72583.1 - 0.0029 17.4 2.2 0.0047 16.7 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW72583.1 - 0.019 14.6 1.0 0.054 13.1 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW72583.1 - 0.35 11.1 8.0 0.092 12.9 3.4 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW72583.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Hpt PF01627.18 EIW72586.1 - 9.1e-12 44.8 0.3 1.2e-11 44.4 0.2 1.2 1 0 0 1 1 1 1 Hpt domain COG4 PF08318.7 EIW72587.1 - 3.4e-54 183.8 0.0 2.4e-52 177.7 0.0 2.1 1 1 0 1 1 1 1 COG4 transport protein HSCB_C PF07743.8 EIW72587.1 - 2 8.9 11.8 0.21 12.0 0.2 3.8 4 0 0 4 4 4 0 HSCB C-terminal oligomerisation domain DUF2347 PF09804.4 EIW72588.1 - 1.1e-45 156.1 0.0 1.5e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EIW72588.1 - 0.00012 21.7 0.2 0.00045 19.9 0.0 2.0 2 0 0 2 2 2 1 Stabilization of polarity axis Rootletin PF15035.1 EIW72589.1 - 0.0065 16.4 0.1 0.0065 16.4 0.1 2.2 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion CI-B14_5a PF07347.7 EIW72591.1 - 0.096 12.4 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) PIP5K PF01504.13 EIW72592.1 - 6.7e-55 185.9 0.0 1.1e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Spc7 PF08317.6 EIW72592.1 - 0.16 10.6 3.1 0.3 9.7 2.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CAP_N PF01213.14 EIW72592.1 - 0.59 9.3 0.0 0.59 9.3 0.0 3.2 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal MUG113 PF13455.1 EIW72593.1 - 4.3e-16 59.1 0.0 9.7e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EIW72593.1 - 5.9e-09 36.2 0.1 4.9e-08 33.2 0.1 2.4 1 1 0 1 1 1 1 T5orf172 domain Cse1 PF08506.5 EIW72594.1 - 1.3e-133 445.1 0.0 1.7e-133 444.7 0.0 1.2 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EIW72594.1 - 2.2e-123 411.8 0.5 7.5e-123 410.0 0.0 1.8 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EIW72594.1 - 5.6e-16 58.2 0.0 3.4e-15 55.7 0.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain HHV6-IE PF03753.8 EIW72594.1 - 0.0016 16.0 0.2 0.0023 15.5 0.1 1.1 1 0 0 1 1 1 1 Human herpesvirus 6 immediate early protein SRI PF08236.6 EIW72594.1 - 0.26 11.2 0.0 0.61 10.0 0.0 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Myc_N PF01056.13 EIW72598.1 - 3.8 6.5 9.4 0.24 10.5 3.1 1.4 2 0 0 2 2 2 0 Myc amino-terminal region UL73_N PF12522.3 EIW72599.1 - 4.4 6.9 6.9 9 5.9 4.8 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Proteasome PF00227.21 EIW72600.1 - 1.8e-42 144.7 0.2 2.6e-42 144.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EIW72600.1 - 7.1e-13 47.5 0.1 1.4e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal BAR_2 PF10455.4 EIW72601.1 - 7.5e-50 169.4 0.0 1.2e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EIW72601.1 - 8.4e-14 51.6 0.0 3.2e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 BAR domain Piwi PF02171.12 EIW72602.1 - 3e-72 243.1 0.0 5.3e-72 242.3 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EIW72602.1 - 1e-12 47.4 0.0 2.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EIW72602.1 - 7.4e-05 22.0 0.2 0.00015 21.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Rotamase PF00639.16 EIW72603.1 - 8e-20 71.3 0.0 1.1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EIW72603.1 - 5.6e-16 58.8 0.0 1.6e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EIW72603.1 - 1.4e-06 28.0 0.1 3e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EIW72603.1 - 0.022 15.3 0.0 0.035 14.7 0.0 1.5 1 1 0 1 1 1 0 PPIC-type PPIASE domain UQ_con PF00179.21 EIW72604.1 - 1e-42 144.8 0.0 1.3e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIW72604.1 - 8.2e-05 22.4 0.0 9.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EIW72604.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UPF0121 PF03661.8 EIW72605.1 - 3.1e-13 49.4 1.1 7.2e-13 48.3 0.8 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) SGL PF08450.7 EIW72607.1 - 3.7e-37 128.0 0.0 5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EIW72607.1 - 3e-08 33.1 0.1 0.11 12.4 0.0 5.0 5 0 0 5 5 5 2 NHL repeat SBBP PF06739.6 EIW72607.1 - 0.00037 20.2 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 1 Beta-propeller repeat Str_synth PF03088.11 EIW72607.1 - 0.001 19.0 0.0 0.17 11.9 0.0 2.8 2 1 0 2 2 2 1 Strictosidine synthase Lactonase PF10282.4 EIW72607.1 - 0.0064 15.6 0.0 0.2 10.6 0.0 2.3 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.15 EIW72607.1 - 0.029 14.3 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 Arylesterase Kelch_6 PF13964.1 EIW72607.1 - 0.1 12.7 0.2 12 6.2 0.0 3.9 5 0 0 5 5 5 0 Kelch motif MFS_1 PF07690.11 EIW72608.1 - 2.5e-21 75.8 31.4 2.5e-21 75.8 21.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4534 PF15049.1 EIW72608.1 - 0.039 13.6 3.2 0.13 11.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4534) SUR7 PF06687.7 EIW72609.1 - 1.3e-05 24.8 19.6 0.0007 19.2 13.6 2.0 1 1 0 1 1 1 1 SUR7/PalI family MFS_1 PF07690.11 EIW72609.1 - 0.019 13.7 12.1 0.026 13.2 8.4 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Band_7_1 PF13421.1 EIW72609.1 - 0.094 12.2 0.1 0.19 11.2 0.0 1.4 2 0 0 2 2 2 0 SPFH domain-Band 7 family PgaD PF13994.1 EIW72609.1 - 0.25 10.8 6.2 0.089 12.2 1.2 2.2 2 1 0 2 2 2 0 PgaD-like protein DUF973 PF06157.6 EIW72609.1 - 0.32 9.9 2.0 0.39 9.6 1.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF973) ABC2_membrane_4 PF12730.2 EIW72609.1 - 0.54 9.3 21.4 0.028 13.5 5.6 2.4 1 1 1 2 2 2 0 ABC-2 family transporter protein 5TM-5TMR_LYT PF07694.7 EIW72609.1 - 2 7.7 9.1 0.17 11.2 2.2 2.0 2 1 0 2 2 2 0 5TMR of 5TMR-LYT PrgI PF12666.2 EIW72609.1 - 7 6.8 18.4 3.2 7.9 0.8 3.3 2 1 1 3 3 3 0 PrgI family protein Rhodanese PF00581.15 EIW72610.1 - 2.7e-17 63.1 0.0 3.5e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Ribonucleas_3_3 PF14622.1 EIW72611.1 - 1.2e-11 44.6 0.0 8.1e-10 38.7 0.0 2.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIW72611.1 - 5.4e-05 23.6 0.0 0.00015 22.2 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 EIW72611.1 - 0.0087 16.6 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif DnaJ PF00226.26 EIW72612.1 - 6.2e-18 64.2 0.2 8e-18 63.9 0.1 1.1 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 EIW72612.1 - 0.14 11.5 0.0 0.3 10.5 0.0 1.6 1 1 0 1 1 1 0 A repeated domain in UCH-protein Ribonuclease_3 PF00636.21 EIW72613.1 - 1.9e-24 86.2 0.0 6e-13 49.2 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIW72613.1 - 2e-09 37.4 0.0 3.8e-06 26.8 0.1 3.8 3 1 0 3 3 3 1 Ribonuclease-III-like Dicer_dimer PF03368.9 EIW72613.1 - 0.0022 17.7 0.0 0.0077 15.9 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain MULE PF10551.4 EIW72614.1 - 1.6e-09 37.8 0.3 1.6e-07 31.3 0.2 2.9 1 1 0 1 1 1 1 MULE transposase domain UCH PF00443.24 EIW72614.1 - 2.7e-09 36.5 0.0 4.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW72614.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase MAD PF05557.8 EIW72615.1 - 1e-05 23.9 24.5 1.4e-05 23.4 17.0 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Baculo_PEP_C PF04513.7 EIW72615.1 - 0.01 15.6 3.1 0.01 15.6 2.1 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.1 EIW72615.1 - 0.059 12.3 28.5 0.17 10.8 5.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Pox_A_type_inc PF04508.7 EIW72615.1 - 0.11 12.3 2.6 7.8 6.5 0.6 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 EIW72615.1 - 0.81 8.8 7.8 0.44 9.6 2.5 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein TSC22 PF01166.13 EIW72615.1 - 2 8.4 15.1 0.56 10.2 0.1 3.6 1 1 2 3 3 3 0 TSC-22/dip/bun family GAS PF13851.1 EIW72615.1 - 2.2 7.4 30.2 0.15 11.2 6.0 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.6 EIW72615.1 - 3.4 7.7 25.7 1 9.4 6.1 2.8 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.7 EIW72615.1 - 6.6 6.4 38.3 2.8 7.6 0.2 3.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.15 EIW72615.1 - 7.6 5.5 34.9 3.9 6.4 1.8 3.1 1 1 1 2 2 2 0 Tropomyosin M PF02370.11 EIW72615.1 - 9.8 6.9 12.8 34 5.2 0.1 4.4 3 1 0 3 3 3 0 M protein repeat DUF869 PF05911.6 EIW72615.1 - 9.8 4.2 31.6 0.092 10.9 16.4 1.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) NAD_binding_6 PF08030.7 EIW72616.1 - 4.2e-23 81.9 0.0 6.3e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EIW72616.1 - 1e-18 67.6 18.5 1e-18 67.6 12.8 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIW72616.1 - 5.5e-17 61.5 0.0 1.1e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EIW72616.1 - 5.9e-06 26.8 0.2 0.055 14.0 0.0 2.6 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain BCS1_N PF08740.6 EIW72616.1 - 0.025 14.2 0.1 0.048 13.2 0.1 1.5 1 0 0 1 1 1 0 BCS1 N terminal Hexapep PF00132.19 EIW72617.1 - 5.6e-14 50.9 6.3 9.8e-10 37.4 0.8 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIW72617.1 - 7e-13 47.9 7.6 1.6e-09 37.1 1.8 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EIW72617.1 - 0.00048 20.0 0.0 0.00069 19.5 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase DUF1071 PF06378.6 EIW72618.1 - 0.034 13.2 0.0 0.063 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Ins_beta PF03488.9 EIW72620.1 - 0.018 14.8 0.1 0.018 14.8 0.1 1.9 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Ras PF00071.17 EIW72625.1 - 8.4e-54 181.3 0.0 9.5e-54 181.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW72625.1 - 9.6e-17 61.5 0.0 1.3e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW72625.1 - 5.8e-07 28.9 0.0 7.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW72625.1 - 0.0015 17.9 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Glyco_hydro_72 PF03198.9 EIW72625.1 - 0.096 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Glucanosyltransferase Sld5 PF05916.6 EIW72626.1 - 1.5e-16 60.6 0.0 2.5e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Lipase_GDSL_2 PF13472.1 EIW72627.1 - 1.4e-06 28.5 0.1 2.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Proteasome PF00227.21 EIW72628.1 - 6.1e-34 116.9 0.0 8.2e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Sec7 PF01369.15 EIW72629.1 - 3.1e-59 199.8 0.0 4.8e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EIW72629.1 - 3.7e-20 72.0 0.0 9.6e-12 44.6 0.0 3.8 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EIW72629.1 - 0.1 12.1 0.9 4.3 6.9 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) DUF3198 PF11433.3 EIW72629.1 - 0.18 11.6 0.1 18 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) Rad51 PF08423.6 EIW72631.1 - 2.2e-09 36.5 0.0 4.1e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Rad51 RecA PF00154.16 EIW72631.1 - 0.00011 21.3 0.0 0.00021 20.4 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EIW72631.1 - 0.00024 20.5 0.3 0.0019 17.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIW72631.1 - 0.0014 18.1 0.0 0.0024 17.3 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain KaiC PF06745.8 EIW72631.1 - 0.017 14.2 0.1 0.069 12.2 0.1 1.8 1 1 0 1 1 1 0 KaiC Nop14 PF04147.7 EIW72632.1 - 0.00044 18.3 34.7 0.00052 18.1 24.1 1.1 1 0 0 1 1 1 1 Nop14-like family AAA_23 PF13476.1 EIW72632.1 - 0.15 12.3 14.8 0.24 11.7 10.2 1.4 1 0 0 1 1 1 0 AAA domain CENP-T PF15511.1 EIW72632.1 - 2.1 7.5 31.9 0.038 13.2 16.2 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Paf1 PF03985.8 EIW72632.1 - 3 6.4 39.2 4.6 5.8 27.1 1.2 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 EIW72632.1 - 5 5.0 28.3 7.8 4.4 19.6 1.3 1 0 0 1 1 1 0 CDC45-like protein SNF2_N PF00176.18 EIW72633.1 - 2.8e-50 170.8 0.0 2.5e-48 164.4 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW72633.1 - 5.4e-14 51.8 0.0 1.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EIW72633.1 - 9.6e-05 22.5 0.0 0.00038 20.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain HDA2-3 PF11496.3 EIW72633.1 - 0.00011 21.1 0.0 0.00026 19.8 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EIW72633.1 - 0.0003 20.6 0.0 0.022 14.5 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMAS PF02353.15 EIW72634.1 - 4.5e-67 226.0 0.0 1.2e-66 224.5 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EIW72634.1 - 1.9e-08 34.2 0.0 3.9e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW72634.1 - 2.3e-08 34.6 0.0 4.9e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW72634.1 - 2.8e-06 27.7 0.0 6.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW72634.1 - 2.6e-05 23.8 0.0 4.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW72634.1 - 0.00013 22.4 0.0 0.00055 20.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EIW72634.1 - 0.001 18.6 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EIW72634.1 - 0.0011 18.9 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EIW72634.1 - 0.0034 16.9 0.0 0.043 13.3 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_24 PF13578.1 EIW72634.1 - 0.0086 16.8 0.0 0.017 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW72634.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EIW72634.1 - 0.047 13.1 0.1 0.086 12.2 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EIW72634.1 - 0.052 12.5 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EIW72634.1 - 0.086 11.9 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EIW72634.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.5 EIW72634.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF4479 PF14794.1 EIW72634.1 - 0.28 10.7 0.9 2.4 7.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4479) TAFII28 PF04719.9 EIW72635.1 - 1.2e-10 41.0 0.1 2.4e-08 33.6 0.0 2.3 1 1 1 2 2 2 2 hTAFII28-like protein conserved region PBP1_TM PF14812.1 EIW72635.1 - 5.4 7.4 13.1 22 5.4 9.1 1.9 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med22 PF06179.7 EIW72636.1 - 1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Nop53 PF07767.6 EIW72636.1 - 0.38 9.6 4.8 0.71 8.7 2.2 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Nop25 PF09805.4 EIW72636.1 - 2.7 8.0 13.3 1.1 9.3 7.3 1.8 2 1 0 2 2 2 0 Nucleolar protein 12 (25kDa) CobT PF06213.7 EIW72636.1 - 4.4 6.3 21.7 13 4.8 15.0 1.7 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1765 PF08578.5 EIW72637.1 - 1.8e-24 86.2 0.1 2.7e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Dynamin_N PF00350.18 EIW72638.1 - 7.7e-40 136.4 0.0 1.5e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EIW72638.1 - 9.6e-08 31.1 0.0 1e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EIW72638.1 - 0.00024 21.0 0.0 0.00082 19.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW72638.1 - 0.0032 17.9 0.0 0.0083 16.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EIW72638.1 - 0.0048 16.9 0.4 1 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain FeoB_N PF02421.13 EIW72638.1 - 0.075 12.3 0.0 7.1 5.8 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_21 PF13304.1 EIW72638.1 - 0.1 12.5 0.3 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNase_P_Rpp14 PF01900.14 EIW72639.1 - 2.2e-24 85.3 0.0 3.1e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Hormone_1 PF00103.15 EIW72640.1 - 0.058 12.7 1.4 0.11 11.8 0.1 2.0 2 1 0 2 2 2 0 Somatotropin hormone family NAD_binding_10 PF13460.1 EIW72641.1 - 1.6e-08 34.7 0.2 2.6e-08 34.1 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW72641.1 - 2.5e-08 33.6 0.0 0.0033 16.9 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW72641.1 - 3e-07 29.9 0.0 7.6e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family DapB_N PF01113.15 EIW72641.1 - 0.0038 17.1 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EIW72641.1 - 0.016 13.9 0.0 0.3 9.7 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.17 EIW72641.1 - 0.027 14.9 0.1 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_4 PF07993.7 EIW72641.1 - 0.03 13.2 0.0 0.086 11.7 0.0 1.8 2 1 1 3 3 3 0 Male sterility protein Semialdhyde_dh PF01118.19 EIW72641.1 - 0.042 14.1 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 EIW72642.1 - 2.2e-16 59.5 45.4 7e-11 41.4 20.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW72642.1 - 1.8e-10 39.6 21.7 2.9e-10 38.9 15.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW72642.1 - 3e-08 32.7 30.0 1e-07 30.9 7.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Helicase_C PF00271.26 EIW72643.1 - 8.8e-19 67.1 0.0 5.5e-16 58.1 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EIW72643.1 - 3.9e-15 55.7 0.0 7.5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW72643.1 - 0.0096 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Oxidored_FMN PF00724.15 EIW72644.1 - 9e-15 54.4 0.0 1.4e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_7 PF03441.9 EIW72644.1 - 0.063 12.4 0.1 0.094 11.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase HTH_28 PF13518.1 EIW72645.1 - 0.11 12.4 0.1 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain FeoC PF09012.5 EIW72645.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator ER-remodelling PF14755.1 EIW72645.1 - 0.44 10.6 7.1 0.55 10.3 4.9 1.3 1 1 0 1 1 1 0 Intracellular membrane remodeller HTH_20 PF12840.2 EIW72646.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.7 EIW72646.1 - 0.017 14.6 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain Phage_CP76 PF06892.6 EIW72646.1 - 0.018 14.3 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) ANT PF03374.9 EIW72646.1 - 0.022 14.7 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain DDRGK PF09756.4 EIW72646.1 - 0.05 13.0 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain CENP-B_N PF04218.8 EIW72646.1 - 0.099 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain ORC6 PF05460.8 EIW72647.1 - 0.34 9.9 4.0 0.36 9.8 2.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pyr_redox_2 PF07992.9 EIW72648.1 - 1.1e-11 45.0 0.0 7.5e-05 22.6 0.0 3.4 2 2 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW72648.1 - 1.5e-09 38.0 0.1 1.3e-05 25.4 0.1 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW72648.1 - 0.00018 21.6 0.4 0.01 15.9 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIW72648.1 - 0.0013 17.7 0.0 0.042 12.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein TrkA_N PF02254.13 EIW72648.1 - 0.0024 17.8 0.3 0.17 11.8 0.0 2.5 2 1 0 2 2 2 1 TrkA-N domain K_oxygenase PF13434.1 EIW72648.1 - 0.0039 16.1 0.2 0.015 14.2 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EIW72648.1 - 0.0079 15.9 1.1 15 5.3 0.2 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EIW72648.1 - 0.12 10.9 0.1 12 4.4 0.1 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EIW72649.1 - 4e-11 43.1 0.0 7.8e-10 38.9 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW72649.1 - 2.9e-08 33.9 0.0 3.2e-05 24.2 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW72649.1 - 0.00039 20.5 0.0 0.0025 17.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIW72649.1 - 0.00095 18.1 0.2 0.02 13.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.1 EIW72649.1 - 0.002 17.1 0.0 0.0037 16.2 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EIW72649.1 - 0.21 10.1 2.4 7 5.1 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_3 PF01494.14 EIW72649.1 - 0.83 8.6 2.4 3.2 6.6 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain Ribosomal_S17 PF00366.15 EIW72651.1 - 1.5e-18 66.5 1.1 2.1e-18 66.1 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 PGP_phosphatase PF09419.5 EIW72653.1 - 3.2e-40 137.2 0.0 1.5e-36 125.3 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Voldacs PF03517.8 EIW72654.1 - 5.3e-19 68.4 0.9 1.1e-18 67.4 0.6 1.5 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling YchF-GTPase_C PF06071.8 EIW72655.1 - 8.3e-36 121.6 0.0 1.9e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EIW72655.1 - 1.3e-14 54.1 0.0 3.9e-14 52.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW72655.1 - 8.9e-06 25.0 0.0 1.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 EIW72655.1 - 0.07 13.9 0.1 0.32 11.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EIW72655.1 - 0.081 12.7 0.1 5.8 6.7 0.1 2.7 1 1 2 3 3 3 0 Dynamin family dCMP_cyt_deam_1 PF00383.17 EIW72656.1 - 5.5e-15 54.8 0.0 7.3e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EIW72656.1 - 4.3e-09 36.4 0.3 7.7e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EIW72656.1 - 0.025 13.9 1.5 1 8.6 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases UDPGP PF01704.13 EIW72657.1 - 2.7e-180 599.3 0.3 3.3e-180 599.1 0.2 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NAD_kinase PF01513.16 EIW72658.1 - 1.1e-45 155.6 0.0 1.5e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EIW72658.1 - 0.0076 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain HTH_Tnp_Tc5 PF03221.11 EIW72659.1 - 3.2e-08 33.2 0.0 6.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SecM PF06558.7 EIW72659.1 - 0.018 14.7 0.4 0.027 14.1 0.3 1.3 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) DDE_1 PF03184.14 EIW72659.1 - 0.079 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_28 PF13518.1 EIW72659.1 - 0.097 12.6 0.0 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain zf-CCHC PF00098.18 EIW72660.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW72660.1 - 0.33 11.1 8.4 0.087 13.0 3.7 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW72660.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.18 EIW72661.1 - 0.00046 19.9 1.5 0.00076 19.2 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW72661.1 - 0.027 14.6 5.3 0.046 13.9 3.7 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain zf-CCHC_6 PF15288.1 EIW72661.1 - 0.053 13.2 0.6 0.15 11.7 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle B56 PF01603.15 EIW72661.1 - 0.36 9.3 2.3 0.47 8.9 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW72662.1 - 0.047 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Beta_elim_lyase PF01212.16 EIW72663.1 - 5e-68 229.3 0.0 6.7e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EIW72663.1 - 2.6e-05 23.3 0.0 9e-05 21.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIW72663.1 - 0.00014 20.2 0.0 0.00026 19.3 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EIW72663.1 - 0.0096 14.9 0.1 0.04 12.9 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aconitase PF00330.15 EIW72663.1 - 0.025 13.0 0.1 0.059 11.8 0.1 1.6 2 0 0 2 2 2 0 Aconitase family (aconitate hydratase) SET PF00856.23 EIW72664.1 - 5.5e-06 26.7 0.0 5.5e-06 26.7 0.0 2.7 2 1 0 2 2 2 1 SET domain Tet_JBP PF12851.2 EIW72665.1 - 1.2e-05 24.7 0.0 1.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Alpha_kinase PF02816.13 EIW72666.1 - 1.8e-13 50.5 0.1 1.3e-12 47.7 0.0 2.5 2 1 0 2 2 2 1 Alpha-kinase family PseudoU_synth_1 PF01416.15 EIW72666.1 - 0.12 12.7 0.4 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 tRNA pseudouridine synthase BRF1 PF07741.8 EIW72668.1 - 0.21 11.8 7.3 0.095 12.9 3.4 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW72668.1 - 0.58 8.6 1.9 0.76 8.3 1.3 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.18 EIW72669.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW72669.1 - 0.33 11.1 8.4 0.087 13.0 3.7 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW72669.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW72670.1 - 0.05 12.9 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Dapper PF15268.1 EIW72671.1 - 0.045 12.5 2.2 0.047 12.4 1.5 1.0 1 0 0 1 1 1 0 Dapper Matrilin_ccoil PF10393.4 EIW72671.1 - 0.15 11.4 0.9 0.25 10.7 0.6 1.5 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin bZIP_1 PF00170.16 EIW72671.1 - 0.28 11.1 3.5 0.39 10.6 2.4 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF3591 PF12157.3 EIW72672.1 - 3.2e-155 516.9 0.0 3.2e-155 516.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EIW72672.1 - 2e-06 27.3 1.7 4.5e-06 26.2 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle BCA_ABC_TP_C PF12399.3 EIW72672.1 - 0.0061 16.2 0.2 0.013 15.1 0.2 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter Glyco_transf_28 PF03033.15 EIW72673.1 - 4.5e-25 88.0 0.0 8.7e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 EIW72673.1 - 1.9e-23 81.7 1.4 3.5e-11 42.4 0.1 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.24 EIW72673.1 - 1e-13 51.3 0.2 5.5e-11 42.6 0.1 3.5 2 1 1 3 3 3 1 PH domain UDPGT PF00201.13 EIW72673.1 - 7.3e-09 34.6 0.0 1.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_6 PF15406.1 EIW72673.1 - 0.00011 22.2 0.0 0.00039 20.4 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EIW72673.1 - 0.0003 20.6 0.1 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EIW72673.1 - 0.0073 16.5 0.4 0.17 12.1 0.3 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain DUF2621 PF11084.3 EIW72673.1 - 0.16 11.6 0.3 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) NDUF_B7 PF05676.8 EIW72674.1 - 1e-31 108.1 2.9 1.2e-31 107.9 2.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EIW72674.1 - 0.035 13.8 2.4 0.051 13.3 1.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Asp PF00026.18 EIW72675.1 - 1.5e-60 205.1 4.5 2e-59 201.4 3.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW72675.1 - 1e-06 28.7 4.3 2e-06 27.8 1.6 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW72675.1 - 9.3e-05 22.8 1.1 0.02 15.4 0.1 2.8 2 0 0 2 2 2 2 Aspartyl protease DEAD PF00270.24 EIW72677.1 - 9.3e-22 77.3 0.0 4.2e-20 71.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 EIW72677.1 - 7e-17 61.0 0.0 1.6e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EIW72677.1 - 1.4e-09 37.4 0.0 3.3e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Helicase_C PF00271.26 EIW72677.1 - 4.9e-06 26.3 0.0 0.0025 17.6 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DUF1672 PF07901.6 EIW72677.1 - 0.047 12.6 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) ResIII PF04851.10 EIW72677.1 - 0.055 13.3 0.2 0.27 11.0 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Methyltransf_28 PF02636.12 EIW72678.1 - 4.9e-33 114.5 0.0 8e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 EIW72678.1 - 0.0012 19.4 0.0 0.0024 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EIW72678.1 - 0.005 15.8 0.0 0.0072 15.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 EIW72678.1 - 0.047 13.2 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIW72678.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Lyase_1 PF00206.15 EIW72680.1 - 8.1e-97 324.1 0.0 1e-96 323.8 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EIW72680.1 - 1.3e-26 92.4 0.0 2.7e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF619 PF04768.8 EIW72681.1 - 1.2e-34 119.1 0.0 3.4e-21 75.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF619) ubiquitin PF00240.18 EIW72681.1 - 6.2e-15 54.3 0.0 1.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIW72681.1 - 1.6e-10 40.5 0.0 2.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIW72681.1 - 0.016 15.4 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain PRMT5 PF05185.11 EIW72683.1 - 4.4e-150 500.5 0.0 7.3e-150 499.7 0.0 1.3 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase MTS PF05175.9 EIW72683.1 - 0.079 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.11 EIW72683.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.7 EIW72683.1 - 0.19 12.2 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cation_efflux PF01545.16 EIW72684.1 - 2.9e-80 269.3 5.6 9.8e-80 267.6 3.9 1.7 1 1 0 1 1 1 1 Cation efflux family Anoctamin PF04547.7 EIW72684.1 - 0.048 12.3 0.1 0.081 11.5 0.1 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel Zip PF02535.17 EIW72684.1 - 0.2 10.6 16.2 1.1 8.1 11.2 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter Ribosomal_S14 PF00253.16 EIW72685.1 - 8.6e-13 47.4 3.7 1.1e-12 47.1 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PUF PF00806.14 EIW72686.1 - 2.9e-61 199.6 3.8 7e-09 34.6 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 EIW72686.1 - 0.02 15.1 0.2 2.7 8.3 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function DUF260 DAO PF01266.19 EIW72687.1 - 1.2e-46 159.3 0.0 1.8e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.1 EIW72687.1 - 1.5e-08 34.6 0.8 3.8e-08 33.3 0.6 1.7 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.19 EIW72687.1 - 1.5e-07 30.6 4.2 0.00011 21.2 0.2 2.7 3 0 0 3 3 3 2 FAD binding domain EF-hand_8 PF13833.1 EIW72687.1 - 5.3e-07 29.1 1.1 5.3e-06 25.9 0.1 3.1 3 1 1 4 4 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EIW72687.1 - 9.1e-06 24.6 0.3 0.015 14.6 0.0 2.7 2 0 0 2 2 2 2 EF hand FAD_oxidored PF12831.2 EIW72687.1 - 1.1e-05 24.7 0.7 2.4e-05 23.6 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase EF-hand_6 PF13405.1 EIW72687.1 - 0.00013 21.5 0.7 0.0016 18.1 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain Pyr_redox_2 PF07992.9 EIW72687.1 - 0.00026 20.9 0.0 0.00074 19.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW72687.1 - 0.0017 17.4 0.3 0.14 11.2 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 EIW72687.1 - 0.0023 17.8 0.8 0.0096 15.9 0.6 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIW72687.1 - 0.014 14.2 0.5 0.71 8.7 0.3 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EIW72687.1 - 0.042 13.5 1.1 0.054 13.1 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EIW72687.1 - 0.06 12.2 0.1 0.27 10.0 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EIW72687.1 - 0.069 13.5 0.3 0.23 11.8 0.1 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW72687.1 - 0.086 11.2 0.2 0.15 10.5 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Nic96 PF04097.9 EIW72690.1 - 2.2e-171 571.1 0.3 2.8e-171 570.7 0.2 1.1 1 0 0 1 1 1 1 Nup93/Nic96 TPR_4 PF07721.9 EIW72690.1 - 0.64 10.6 11.6 3.4 8.3 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Ras PF00071.17 EIW72691.1 - 2.8e-64 215.3 0.0 3.3e-64 215.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW72691.1 - 2.3e-19 70.0 0.0 3.1e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW72691.1 - 4.8e-13 48.7 0.0 6.3e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW72691.1 - 3.9e-05 22.8 0.0 4.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW72691.1 - 5.9e-05 22.5 0.0 0.00015 21.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW72691.1 - 0.00044 20.1 0.0 0.00076 19.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW72691.1 - 0.0032 16.6 0.0 0.041 13.0 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EIW72691.1 - 0.019 14.2 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 EIW72691.1 - 0.03 14.3 0.0 0.08 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EIW72691.1 - 0.035 13.6 0.0 0.097 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EIW72691.1 - 0.06 12.3 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_22 PF13401.1 EIW72691.1 - 0.067 13.3 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EIW72691.1 - 0.068 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 EIW72691.1 - 0.069 12.3 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 EIW72691.1 - 0.098 12.8 0.0 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.18 EIW72691.1 - 0.14 10.9 0.0 0.33 9.6 0.0 1.5 2 0 0 2 2 2 0 MCM2/3/5 family Hydantoinase_B PF02538.9 EIW72692.1 - 3.4e-177 589.8 0.0 4.4e-177 589.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EIW72692.1 - 2.2e-89 299.4 0.1 7.6e-89 297.6 0.0 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIW72692.1 - 9.1e-55 184.8 0.1 5.4e-52 175.8 0.0 2.8 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region ActA PF05058.7 EIW72693.1 - 0.0015 16.6 1.8 0.0027 15.7 1.3 1.3 1 0 0 1 1 1 1 ActA Protein DUF2205 PF10224.4 EIW72694.1 - 0.025 14.1 1.4 0.025 14.1 1.0 1.9 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) BRCT PF00533.21 EIW72694.1 - 0.036 14.2 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain ATG16 PF08614.6 EIW72694.1 - 0.11 12.3 4.5 0.14 11.9 0.7 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF677 PF05055.7 EIW72694.1 - 0.21 10.2 5.9 0.2 10.2 0.7 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF677) HR1 PF02185.11 EIW72694.1 - 0.22 11.2 4.3 1.5 8.6 0.3 2.2 2 0 0 2 2 2 0 Hr1 repeat Prefoldin PF02996.12 EIW72694.1 - 0.43 10.2 4.1 0.3 10.7 0.4 2.2 3 0 0 3 3 3 0 Prefoldin subunit Phage_GP20 PF06810.6 EIW72694.1 - 0.74 9.2 5.0 1.2 8.5 0.6 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Ax_dynein_light PF10211.4 EIW72694.1 - 2.2 8.1 8.7 0.56 10.0 1.3 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain IncA PF04156.9 EIW72694.1 - 3.1 7.3 5.4 10 5.6 0.4 2.2 2 0 0 2 2 2 0 IncA protein SET PF00856.23 EIW72695.1 - 2.8e-11 43.9 0.5 3.6e-09 37.1 0.3 2.5 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.17 EIW72695.1 - 2.5e-05 23.8 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Methyltransf_28 PF02636.12 EIW72696.1 - 1.1e-66 224.7 0.0 1.4e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Dynamitin PF04912.9 EIW72697.1 - 1.5e-18 66.7 7.9 2.6e-13 49.5 0.4 3.2 2 2 0 2 2 2 2 Dynamitin BLOC1_2 PF10046.4 EIW72697.1 - 0.2 11.7 2.0 0.78 9.9 0.2 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.8 EIW72697.1 - 0.59 10.8 3.0 6.7 7.5 0.1 3.3 3 1 0 3 3 3 0 Occludin homology domain DUF883 PF05957.8 EIW72697.1 - 0.87 10.0 6.4 12 6.4 0.9 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TBPIP PF07106.8 EIW72697.1 - 1.8 8.1 4.9 1.2 8.6 0.7 2.3 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 EIW72697.1 - 1.9 8.3 5.8 7.1 6.4 0.9 3.5 4 1 0 4 4 4 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 EIW72697.1 - 3.5 7.3 7.3 1.6 8.4 1.9 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.1 EIW72697.1 - 3.5 8.1 7.1 4.4 7.8 0.2 3.7 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF572 PF04502.8 EIW72698.1 - 0.98 8.5 12.9 1.8 7.7 8.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Fra10Ac1 PF09725.4 EIW72699.1 - 2.9e-47 159.5 0.1 5e-47 158.8 0.1 1.4 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 zf-C4_Topoisom PF01396.14 EIW72699.1 - 0.065 12.7 0.2 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger OTCace_N PF02729.16 EIW72700.1 - 5.6e-42 142.7 0.0 8.2e-42 142.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EIW72700.1 - 6.7e-41 139.7 0.0 1.2e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Glyco_hydro_4 PF02056.11 EIW72700.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase TrkH PF02386.11 EIW72701.1 - 2e-69 233.8 13.2 5.4e-69 232.4 2.2 2.1 2 0 0 2 2 2 2 Cation transport protein Ribosomal_L30 PF00327.15 EIW72702.1 - 1.7e-11 43.5 0.0 2.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e zf-C2H2_jaz PF12171.3 EIW72703.1 - 9.5e-10 38.3 4.8 1.5e-09 37.7 3.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW72703.1 - 0.0014 18.7 3.5 0.0021 18.1 2.5 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIW72703.1 - 0.014 15.5 2.2 0.018 15.1 1.2 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) HIRA_B PF09453.5 EIW72706.1 - 0.026 14.0 0.3 0.064 12.8 0.2 1.7 1 0 0 1 1 1 0 HIRA B motif CsbD PF05532.7 EIW72710.1 - 1.1e-09 37.8 10.9 6.1e-05 22.6 1.3 3.1 2 1 1 3 3 3 3 CsbD-like MFS_1 PF07690.11 EIW72711.1 - 3.4e-35 121.4 49.7 7.5e-35 120.2 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PAGK PF15284.1 EIW72711.1 - 3.5 7.4 5.7 0.65 9.7 0.1 2.7 3 0 0 3 3 3 0 Phage-encoded virulence factor WD40 PF00400.27 EIW72712.1 - 3.2e-17 61.6 12.1 2e-08 33.8 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat COX6A PF02046.10 EIW72713.1 - 1.6e-34 118.2 2.0 1.8e-34 118.1 1.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Peroxin-3 PF04882.7 EIW72714.1 - 2.7e-93 313.0 0.0 3.9e-93 312.5 0.0 1.2 1 0 0 1 1 1 1 Peroxin-3 Acetyltransf_1 PF00583.19 EIW72715.1 - 8.8e-14 51.3 0.0 1.4e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW72715.1 - 0.0002 21.4 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW72715.1 - 0.00029 20.5 0.0 0.0006 19.5 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EIW72715.1 - 0.011 15.9 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW72715.1 - 0.063 13.1 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain tRNA-synt_1b PF00579.20 EIW72716.1 - 7.2e-68 228.8 0.0 9.2e-68 228.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RNase_T PF00929.19 EIW72717.1 - 1.8e-14 54.3 0.0 9.9e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Exonuclease RRM_1 PF00076.17 EIW72718.1 - 3.6e-11 42.5 0.0 8.4e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EIW72718.1 - 8.5e-07 28.9 0.1 5.9e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 PWI domain RRM_6 PF14259.1 EIW72718.1 - 2.4e-05 24.2 0.0 5.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1323 PF07037.6 EIW72718.1 - 0.0091 16.1 0.2 2.3 8.3 0.0 2.8 2 0 0 2 2 2 1 Putative transcription regulator (DUF1323) Sec63 PF02889.11 EIW72719.1 - 1.5e-37 129.4 0.0 1.4e-36 126.3 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EIW72719.1 - 1e-17 63.6 1.1 2.2e-17 62.5 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain Fungal_trans_2 PF11951.3 EIW72719.1 - 0.018 13.6 1.0 1.6 7.2 0.2 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain Atg14 PF10186.4 EIW72719.1 - 0.19 10.6 3.0 1.9 7.3 2.6 2.0 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Pkinase PF00069.20 EIW72720.1 - 1.9e-27 96.0 0.0 2.9e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72720.1 - 9.2e-17 60.9 0.0 1.5e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CBM_2 PF00553.14 EIW72720.1 - 1.7 8.7 9.2 1.1 9.2 0.8 2.6 2 0 0 2 2 2 0 Cellulose binding domain NUFIP1 PF10453.4 EIW72721.1 - 1.1e-16 60.1 5.5 1.1e-16 60.1 3.8 2.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EIW72721.1 - 3e-09 36.3 4.9 6e-09 35.3 3.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) APC_CDC26 PF10471.4 EIW72721.1 - 0.12 13.1 0.0 0.12 13.1 0.0 3.3 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 zf-CCCH_2 PF14608.1 EIW72721.1 - 0.75 9.8 17.9 3 7.9 0.7 2.7 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type AF-4 PF05110.8 EIW72721.1 - 1.5 6.6 19.5 2.3 5.9 13.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MULE PF10551.4 EIW72723.1 - 5.4e-13 48.9 0.2 7.4e-11 42.0 0.2 2.8 1 1 0 1 1 1 1 MULE transposase domain UCH PF00443.24 EIW72723.1 - 1.9e-06 27.1 0.0 5.4e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW72723.1 - 0.024 14.1 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Cmc1 PF08583.5 EIW72724.1 - 3.2e-17 62.0 0.9 4.5e-17 61.5 0.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EIW72724.1 - 0.064 13.1 0.9 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 CHCH domain COX17 PF05051.8 EIW72724.1 - 0.18 11.8 1.7 4.5 7.3 0.1 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF1635 PF07795.6 EIW72725.1 - 0.086 12.1 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) NUDIX PF00293.23 EIW72726.1 - 2.6e-13 49.7 0.1 1.7e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain NUDIX PF00293.23 EIW72727.1 - 5.1e-05 22.9 0.0 7.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF572 PF04502.8 EIW72728.1 - 1.7e-77 260.8 8.3 2e-77 260.6 5.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.7 EIW72728.1 - 0.018 14.3 4.4 0.023 14.0 0.6 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF866 PF05907.8 EIW72728.1 - 0.022 14.2 0.3 0.04 13.4 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Benyvirus_14KDa PF07255.6 EIW72728.1 - 0.032 14.0 0.2 0.14 12.0 0.1 1.9 1 1 1 2 2 2 0 Benyvirus 14KDa protein PhnA_Zn_Ribbon PF08274.7 EIW72728.1 - 1.3 8.8 3.5 0.41 10.4 0.3 1.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon eRF1_2 PF03464.10 EIW72730.1 - 5.2e-42 143.3 0.0 9.7e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EIW72730.1 - 9.3e-38 128.9 0.0 1.7e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EIW72730.1 - 5.2e-24 84.3 0.0 9.2e-24 83.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Glutaredoxin PF00462.19 EIW72731.1 - 8.4e-18 64.1 0.0 2e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.15 EIW72731.1 - 3.9e-07 29.6 0.0 9.2e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIW72731.1 - 0.033 14.2 0.0 0.4 10.8 0.0 2.4 2 1 1 3 3 3 0 Thioredoxin-like GST_N_3 PF13417.1 EIW72731.1 - 0.089 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ArsC PF03960.10 EIW72731.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 ArsC family Not1 PF04054.10 EIW72732.1 - 9.3e-92 307.7 0.0 1.6e-91 307.0 0.0 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EIW72732.1 - 2.3e-48 163.6 0.0 6.5e-48 162.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Glyco_hydro_31 PF01055.21 EIW72732.1 - 0.5 9.1 0.0 0.81 8.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Peptidase_M19 PF01244.16 EIW72733.1 - 5.1e-103 344.3 0.0 6.4e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF1467 PF07330.7 EIW72733.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) Peptidase_M24 PF00557.19 EIW72734.1 - 2.2e-56 190.7 0.0 3e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EIW72734.1 - 6.7e-27 93.5 0.0 3.1e-26 91.3 0.0 2.0 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain IPPT PF01715.12 EIW72734.1 - 0.046 12.7 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 IPP transferase Pkinase PF00069.20 EIW72735.1 - 4.3e-51 173.5 0.1 5.5e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72735.1 - 3.1e-24 85.4 0.6 2.2e-23 82.6 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EIW72735.1 - 0.00053 19.3 1.0 0.012 14.9 0.2 2.2 1 1 1 2 2 2 1 RIO1 family Pox_ser-thr_kin PF05445.6 EIW72735.1 - 0.00077 18.3 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EIW72735.1 - 0.08 12.6 0.8 0.19 11.4 0.1 1.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family GBP_repeat PF02526.9 EIW72735.1 - 0.12 11.8 0.5 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Glycophorin-binding protein TPR_1 PF00515.23 EIW72736.1 - 4e-29 98.9 8.3 2.7e-07 29.8 0.4 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat APC8 PF04049.8 EIW72736.1 - 3.7e-28 98.0 0.0 9e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 EIW72736.1 - 2.3e-23 81.6 15.4 1.1e-07 31.4 0.6 6.0 5 1 2 7 7 7 5 TPR repeat TPR_2 PF07719.12 EIW72736.1 - 4.2e-23 79.3 11.9 0.0021 17.8 0.4 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 EIW72736.1 - 9.5e-17 59.4 6.8 0.003 17.2 0.0 7.5 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIW72736.1 - 6.6e-15 54.2 11.5 0.046 14.3 0.2 8.7 6 1 2 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EIW72736.1 - 1.3e-11 44.7 9.5 0.00036 21.1 0.5 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIW72736.1 - 1.5e-11 44.0 23.7 0.00087 19.1 0.2 7.2 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EIW72736.1 - 1.2e-10 41.0 9.5 0.059 13.2 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EIW72736.1 - 3.5e-08 32.6 13.0 0.11 12.3 0.0 8.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW72736.1 - 1.6e-06 28.1 5.0 1.2 9.7 0.3 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIW72736.1 - 2.2e-06 27.4 6.3 0.66 10.3 0.2 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW72736.1 - 2.1e-05 24.7 6.4 0.29 11.5 0.5 6.0 4 1 1 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.5 EIW72736.1 - 0.017 13.9 2.1 3.1 6.4 0.0 3.3 1 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_18 PF13512.1 EIW72736.1 - 0.62 10.0 4.8 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PITH PF06201.8 EIW72737.1 - 4.3e-26 91.5 0.0 5.5e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain Rap_GAP PF02145.10 EIW72738.1 - 1e-41 142.4 0.0 1.6e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EIW72738.1 - 3.7e-06 26.2 0.3 7.4e-06 25.2 0.2 1.5 1 1 0 1 1 1 1 Tuberin DUF4405 PF14358.1 EIW72739.1 - 0.098 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) DUF4234 PF14018.1 EIW72740.1 - 0.35 10.6 6.6 0.34 10.6 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Med26 PF08711.6 EIW72741.1 - 1.1e-07 31.1 0.0 2.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SQS_PSY PF00494.14 EIW72742.1 - 2.7e-41 141.6 0.1 5.2e-41 140.7 0.0 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase RNase_T PF00929.19 EIW72743.1 - 5e-24 85.4 0.0 6.4e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EIW72743.1 - 0.00075 19.0 0.0 0.0018 17.8 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease AntA PF08346.7 EIW72743.1 - 0.012 15.7 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 AntA/AntB antirepressor CIA30 PF08547.7 EIW72745.1 - 4.5e-12 46.0 0.0 7.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) PI-PLC-X PF00388.14 EIW72746.1 - 6.4e-07 28.8 0.0 2.2e-06 27.1 0.0 1.8 2 1 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain Pkinase PF00069.20 EIW72748.1 - 5.6e-71 238.7 0.0 6.3e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72748.1 - 1.5e-51 174.9 0.0 1.8e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW72748.1 - 2.5e-05 23.4 0.0 0.0001 21.3 0.0 1.9 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIW72748.1 - 0.00057 19.2 0.0 0.00097 18.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIW72748.1 - 0.0013 17.8 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIW72748.1 - 0.0019 17.1 0.0 0.0048 15.7 0.0 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.18 EIW72748.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family NAD_binding_11 PF14833.1 EIW72749.1 - 2.9e-31 108.0 0.0 5.4e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EIW72749.1 - 2.1e-25 89.4 0.7 1.9e-24 86.3 0.5 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TFIIE_alpha PF02002.12 EIW72751.1 - 1.5e-06 27.6 0.4 3.7e-06 26.3 0.3 1.7 1 1 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EIW72751.1 - 0.019 14.2 1.4 0.045 13.0 1.0 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding ADK_lid PF05191.9 EIW72751.1 - 0.03 13.9 0.7 0.079 12.6 0.5 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid TFIIE-A_C-term PF11521.3 EIW72751.1 - 8.8 6.3 7.9 44 4.1 4.3 2.8 2 1 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Alpha_kinase PF02816.13 EIW72752.1 - 1e-13 51.3 0.1 3.2e-13 49.7 0.0 1.9 1 1 0 1 1 1 1 Alpha-kinase family 60KD_IMP PF02096.15 EIW72758.1 - 4.7e-24 85.1 0.0 3.9e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 60Kd inner membrane protein SAM_2 PF07647.12 EIW72759.1 - 9.3e-14 51.0 0.0 1.5e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EIW72759.1 - 5e-13 48.2 2.8 5.1e-07 28.9 0.0 3.3 3 1 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EIW72759.1 - 3.7e-11 42.4 2.1 2.7e-05 23.6 0.3 2.9 3 0 0 3 3 3 2 Variant SH3 domain SAM_1 PF00536.25 EIW72759.1 - 7.2e-10 38.9 0.1 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EIW72759.1 - 1.3e-08 35.1 0.0 2.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_2 PF07653.12 EIW72759.1 - 1.6e-06 27.5 0.8 1.1e-05 24.8 0.2 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 EIW72759.1 - 7.8e-05 22.7 2.5 0.11 12.6 0.4 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain Staphopain_pro PF14731.1 EIW72759.1 - 0.16 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Staphopain proregion 4HBT PF03061.17 EIW72760.1 - 0.00092 19.2 1.3 0.22 11.6 0.0 3.1 2 1 0 2 2 2 2 Thioesterase superfamily p450 PF00067.17 EIW72761.1 - 1.7e-39 135.6 0.1 1.1e-20 73.6 0.0 3.6 3 1 0 3 3 3 3 Cytochrome P450 Pyr_redox_2 PF07992.9 EIW72762.1 - 1.6e-32 113.0 0.7 1.7e-30 106.4 0.5 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EIW72762.1 - 1.9e-17 62.5 0.1 6.3e-17 60.9 0.0 1.9 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 EIW72762.1 - 1.5e-13 50.9 3.2 3.7e-11 43.2 0.1 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW72762.1 - 8.4e-11 42.3 0.0 8e-07 29.3 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EIW72762.1 - 3.6e-08 33.0 0.0 1.7e-07 30.8 0.0 2.2 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.1 EIW72762.1 - 1.7e-05 23.9 0.0 0.12 11.2 0.0 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EIW72762.1 - 0.00042 19.3 3.9 0.18 10.6 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIW72762.1 - 0.005 16.6 0.0 14 5.4 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Reductase_C PF14759.1 EIW72762.1 - 0.011 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Reductase C-terminal Lycopene_cycl PF05834.7 EIW72762.1 - 0.013 14.3 0.0 0.41 9.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DUF563 PF04577.9 EIW72763.1 - 1.3e-19 70.9 0.1 5.1e-19 68.9 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF563) TPM PF04536.9 EIW72763.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase IBR PF01485.16 EIW72764.1 - 9.9e-16 57.3 15.1 1.7e-10 40.6 0.5 4.5 4 1 1 5 5 5 2 IBR domain RWD PF05773.17 EIW72764.1 - 9.6e-12 44.8 0.0 2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 EIW72764.1 - 0.014 15.2 13.4 0.014 15.2 9.3 3.7 3 0 0 3 3 3 0 Ring finger domain Porphobil_deam PF01379.15 EIW72767.1 - 1.1e-61 207.5 0.0 1.4e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EIW72767.1 - 4.2e-15 55.5 0.1 1.8e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain Septin PF00735.13 EIW72768.1 - 2.1e-112 374.7 0.1 2.9e-112 374.2 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIW72768.1 - 3.3e-08 33.4 0.0 6.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW72768.1 - 4.3e-07 29.2 0.0 9.3e-07 28.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIW72768.1 - 2e-05 24.1 0.7 0.00062 19.2 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EIW72768.1 - 0.00095 19.3 2.1 0.015 15.4 0.1 3.1 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW72768.1 - 0.0016 18.4 0.3 0.0079 16.1 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.11 EIW72768.1 - 0.0033 16.5 0.0 0.0071 15.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.22 EIW72768.1 - 0.0036 17.6 0.0 0.011 16.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 EIW72768.1 - 0.0045 17.4 0.0 0.015 15.7 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EIW72768.1 - 0.006 16.0 2.5 0.082 12.3 0.2 2.9 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EIW72768.1 - 0.0062 16.1 0.1 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain DegS PF05384.6 EIW72768.1 - 0.0099 15.1 4.9 0.17 11.0 3.0 2.5 2 1 0 2 2 2 1 Sensor protein DegS Ras PF00071.17 EIW72768.1 - 0.012 15.0 0.2 0.031 13.6 0.1 1.7 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.18 EIW72768.1 - 0.013 15.3 4.0 0.86 9.3 0.0 2.8 2 1 1 3 3 3 0 Dynamin family MobB PF03205.9 EIW72768.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 EIW72768.1 - 0.018 14.1 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_10 PF12846.2 EIW72768.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EIW72768.1 - 0.022 14.6 0.1 0.076 12.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 EIW72768.1 - 0.04 12.7 0.2 0.089 11.6 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 EIW72768.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EIW72768.1 - 0.07 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3552 PF12072.3 EIW72768.1 - 0.074 12.2 5.5 0.13 11.4 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Sigma54_activat PF00158.21 EIW72768.1 - 0.08 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EIW72768.1 - 0.11 12.0 0.9 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family SF3b10 PF07189.6 EIW72769.1 - 4.3e-34 116.1 0.0 5.4e-34 115.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) NOT2_3_5 PF04153.13 EIW72770.1 - 1.7e-20 73.2 0.3 1.7e-20 73.2 0.2 1.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family SUR7 PF06687.7 EIW72771.1 - 0.0021 17.6 6.8 0.0087 15.6 4.7 2.0 1 1 0 1 1 1 1 SUR7/PalI family A_deaminase PF00962.17 EIW72774.1 - 1e-108 363.1 0.6 1.3e-108 362.8 0.4 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Rick_17kDa_Anti PF05433.10 EIW72775.1 - 0.012 15.2 3.2 0.013 15.1 0.4 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain DUF1510 PF07423.6 EIW72775.1 - 0.12 11.7 0.6 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Glyco_transf_90 PF05686.7 EIW72778.1 - 1.4e-20 73.3 1.4 1.1e-19 70.4 0.2 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 Cpn60_TCP1 PF00118.19 EIW72779.1 - 2.3e-133 445.3 0.2 2.6e-133 445.1 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PUF PF00806.14 EIW72780.1 - 1.4e-09 36.9 0.0 0.061 12.8 0.0 4.9 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat DUF663 PF04950.7 EIW72781.1 - 4.8e-91 304.7 0.0 8.4e-91 304.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EIW72781.1 - 1.3e-24 85.5 0.0 3.5e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.1 EIW72781.1 - 2.9e-05 24.1 0.5 9.1e-05 22.5 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 EIW72781.1 - 6.6e-05 23.7 0.0 6.6e-05 23.7 0.0 3.5 4 1 0 4 4 2 1 AAA domain MMR_HSR1 PF01926.18 EIW72781.1 - 8.6e-05 22.4 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EIW72781.1 - 0.00025 20.5 0.5 0.00058 19.3 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 EIW72781.1 - 0.00058 20.0 0.1 0.003 17.7 0.0 2.2 3 0 0 3 3 1 1 AAA domain ABC_tran PF00005.22 EIW72781.1 - 0.0025 18.0 0.0 0.0025 18.0 0.0 2.1 2 0 0 2 2 1 1 ABC transporter MobB PF03205.9 EIW72781.1 - 0.0026 17.4 0.1 0.006 16.2 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EIW72781.1 - 0.0032 17.6 0.0 0.0092 16.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EIW72781.1 - 0.0034 17.6 0.1 0.0034 17.6 0.0 3.1 5 0 0 5 5 2 1 AAA domain AAA_33 PF13671.1 EIW72781.1 - 0.0084 15.9 1.7 0.016 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EIW72781.1 - 0.011 14.5 0.1 0.011 14.5 0.1 1.9 2 0 0 2 2 1 0 ArgK protein NB-ARC PF00931.17 EIW72781.1 - 0.013 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EIW72781.1 - 0.014 15.0 0.8 0.022 14.4 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_14 PF13173.1 EIW72781.1 - 0.021 14.7 0.0 0.062 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIW72781.1 - 0.029 13.7 0.0 0.1 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EIW72781.1 - 0.036 14.2 0.0 0.093 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EIW72781.1 - 0.043 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 EIW72781.1 - 0.043 13.2 0.1 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EIW72781.1 - 0.045 12.9 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 EIW72781.1 - 0.058 12.3 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.9 EIW72781.1 - 0.075 12.7 0.1 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF1508 PF07411.7 EIW72782.1 - 0.031 13.7 0.2 0.072 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) Pkinase PF00069.20 EIW72783.1 - 3.5e-59 200.0 0.0 5.9e-59 199.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72783.1 - 1.2e-33 116.3 0.0 9.9e-33 113.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW72783.1 - 0.0007 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EIW72783.1 - 0.032 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EIW72783.1 - 0.047 13.0 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family LVIVD PF08309.6 EIW72785.1 - 0.18 10.8 0.2 0.4 9.7 0.1 1.5 1 0 0 1 1 1 0 LVIVD repeat Bromodomain PF00439.20 EIW72786.1 - 3.6e-13 49.2 0.0 6.5e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.20 EIW72787.1 - 5.1e-64 215.9 0.0 9.5e-64 215.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72787.1 - 2.2e-35 121.9 0.0 3.6e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EIW72787.1 - 2.8e-21 74.9 29.4 4.4e-12 45.5 6.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.11 EIW72787.1 - 7.6e-20 70.4 15.4 3.6e-11 42.6 5.5 2.4 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.19 EIW72787.1 - 3.9e-10 40.0 2.0 5.4e-10 39.6 0.1 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EIW72787.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C2 PF00168.25 EIW72787.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 C2 domain FYVE_2 PF02318.11 EIW72787.1 - 1.6 8.6 16.9 2.4 8.0 3.1 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger WLM PF08325.5 EIW72788.1 - 1.4e-53 181.5 10.3 2.5e-53 180.6 5.4 2.6 2 1 0 2 2 2 1 WLM domain zf-RanBP PF00641.13 EIW72788.1 - 7.6e-05 21.7 0.7 0.00014 20.9 0.5 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others MMTV_SAg PF01054.12 EIW72788.1 - 0.046 12.6 0.6 0.079 11.8 0.4 1.3 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen UEV PF05743.8 EIW72790.1 - 6.5e-32 109.7 0.1 1.1e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EIW72790.1 - 2e-27 94.5 0.8 3.9e-27 93.6 0.5 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 EIW72790.1 - 0.026 13.9 0.1 0.056 12.8 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme COG5 PF10392.4 EIW72791.1 - 1.5e-34 118.8 2.0 1.2e-33 115.8 0.5 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 LRR_8 PF13855.1 EIW72792.1 - 0.0011 18.6 5.1 0.66 9.7 0.1 3.3 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EIW72792.1 - 0.0052 16.6 8.8 7.7 6.9 0.1 6.1 7 0 0 7 7 7 2 Leucine Rich Repeat F-box PF00646.28 EIW72792.1 - 0.051 13.2 1.7 2.6 7.8 0.8 2.6 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.2 EIW72792.1 - 0.071 12.7 9.3 1.6 8.4 1.8 4.7 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIW72792.1 - 0.15 11.7 2.6 0.72 9.6 1.8 2.3 1 1 0 1 1 1 0 F-box-like LRR_7 PF13504.1 EIW72792.1 - 0.61 10.5 9.1 22 5.8 0.1 5.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EIW72792.1 - 0.87 9.8 6.9 0.63 10.2 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat SH3_1 PF00018.23 EIW72793.1 - 1.1e-14 53.5 0.1 1.8e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW72793.1 - 3.1e-13 49.0 0.3 5.1e-13 48.3 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW72793.1 - 3.7e-13 48.7 0.0 6.8e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EIW72793.1 - 0.012 15.8 0.4 0.028 14.5 0.3 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain AIRS PF00586.19 EIW72793.1 - 0.026 14.7 0.8 0.053 13.7 0.5 1.5 1 1 0 1 1 1 0 AIR synthase related protein, N-terminal domain PROL5-SMR PF15621.1 EIW72793.1 - 3.1 8.2 14.6 7.3 7.0 6.8 2.3 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Tim17 PF02466.14 EIW72794.1 - 1.6e-34 118.7 7.4 2.3e-34 118.1 5.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Acyltransferase PF01553.16 EIW72795.1 - 4.6e-10 39.0 0.0 0.00027 20.3 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase WD40 PF00400.27 EIW72796.1 - 9.3e-32 107.7 11.9 1e-08 34.7 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Prp19 PF08606.6 EIW72796.1 - 1.1e-29 101.8 1.7 2.2e-29 101.0 1.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 EIW72796.1 - 0.00014 21.7 0.0 0.00051 19.9 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 EIW72796.1 - 0.0083 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF1631 PF07793.6 EIW72796.1 - 0.04 12.0 0.5 0.055 11.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) OB_NTP_bind PF07717.11 EIW72797.1 - 1.3e-26 92.6 0.0 2.9e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EIW72797.1 - 3.4e-25 88.0 0.2 2e-24 85.5 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIW72797.1 - 3.7e-14 52.3 0.0 9.9e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW72797.1 - 4.6e-07 29.4 0.0 1.6e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIW72797.1 - 0.00035 20.7 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EIW72797.1 - 0.0087 14.9 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EIW72797.1 - 0.011 15.4 0.1 0.048 13.4 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 EIW72797.1 - 0.044 13.6 2.3 3.9 7.2 0.0 3.5 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Herpes_ori_bp PF02399.10 EIW72797.1 - 0.064 11.1 0.0 0.099 10.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein MutL_C PF08676.6 EIW72799.1 - 1.1e-24 86.6 0.0 2.4e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EIW72799.1 - 1.2e-19 69.9 0.0 2.4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EIW72799.1 - 1.4e-10 40.9 0.0 3.4e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIW72799.1 - 5.2e-10 39.1 0.1 2e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dicty_REP PF05086.7 EIW72799.1 - 9.4 3.8 5.9 14 3.3 4.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Kelch_3 PF13415.1 EIW72802.1 - 6.1e-28 96.3 6.8 1.4e-07 31.5 0.0 7.3 7 1 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.1 EIW72802.1 - 2.5e-22 78.5 0.3 2.5e-22 78.5 0.2 3.6 4 1 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 EIW72802.1 - 1.1e-16 60.2 11.9 5e-05 22.9 0.0 7.0 6 3 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EIW72802.1 - 1.4e-13 50.3 6.2 9.3e-05 22.4 0.0 6.2 5 2 1 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EIW72802.1 - 2.5e-11 42.8 1.5 2e-05 24.1 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 EIW72802.1 - 3e-10 39.4 4.5 1.4e-05 24.5 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 EIW72802.1 - 1.2e-09 37.9 8.5 0.0002 21.2 0.0 5.3 6 0 0 6 6 6 3 Kelch motif SPT16 PF08644.6 EIW72803.1 - 7.4e-54 181.7 0.3 2.3e-53 180.1 0.2 1.9 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.7 EIW72803.1 - 5.3e-24 84.0 0.2 2.2e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like TFIIH_BTF_p62_N PF08567.6 EIW72803.1 - 0.00092 18.8 0.4 0.0026 17.3 0.0 2.0 3 0 0 3 3 3 1 TFIIH p62 subunit, N-terminal domain Levi_coat PF01819.12 EIW72803.1 - 0.033 13.7 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 Levivirus coat protein DUF1162 PF06650.7 EIW72804.1 - 1e-63 215.1 0.0 2.4e-59 200.8 0.0 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EIW72804.1 - 2.1e-32 111.0 0.0 5.1e-32 109.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EIW72804.1 - 4.9e-08 33.0 0.0 3.4e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 ATG C terminal domain DUF3040 PF11239.3 EIW72804.1 - 0.18 11.8 0.8 0.54 10.3 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) FA_hydroxylase PF04116.8 EIW72805.1 - 1.4e-14 54.4 17.2 1.4e-14 54.4 11.9 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DASH_Dad4 PF08650.5 EIW72806.1 - 4.6e-21 74.5 1.4 5.1e-21 74.3 1.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Cmc1 PF08583.5 EIW72806.1 - 0.051 13.3 0.1 0.068 12.9 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Zn_clus PF00172.13 EIW72807.1 - 1.6e-08 34.3 11.8 2.8e-08 33.5 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_6 PF08030.7 EIW72808.1 - 5.1e-18 65.4 0.0 1.3e-17 64.1 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIW72808.1 - 1.1e-15 57.3 0.0 4.5e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EIW72808.1 - 1.4e-13 51.0 12.8 4.1e-13 49.5 8.1 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EIW72808.1 - 0.00057 20.4 0.0 0.29 11.7 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain R3H PF01424.17 EIW72809.1 - 1.2e-11 44.0 0.0 1.2e-11 44.0 0.0 2.8 4 0 0 4 4 4 1 R3H domain G-patch PF01585.18 EIW72809.1 - 3e-08 33.3 0.0 1e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EIW72809.1 - 4.5e-07 29.6 0.4 2.1e-06 27.4 0.3 2.2 1 0 0 1 1 1 1 DExH-box splicing factor binding site CBM_10 PF02013.11 EIW72809.1 - 1.1 9.5 3.0 2.3 8.5 2.1 1.5 1 0 0 1 1 1 0 Cellulose or protein binding domain HSP70 PF00012.15 EIW72810.1 - 1.9e-269 894.6 7.7 2.2e-269 894.4 5.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIW72810.1 - 8e-17 60.8 0.3 2.7e-15 55.7 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EIW72810.1 - 0.0013 18.6 0.9 0.61 9.9 0.0 3.1 2 2 0 2 2 2 2 Cell division protein FtsA DDR PF08841.5 EIW72810.1 - 0.0018 17.1 0.6 0.035 12.9 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EIW72810.1 - 0.0019 17.8 0.0 0.0053 16.4 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EIW72810.1 - 0.0021 17.2 0.3 0.045 12.8 0.0 2.6 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase Transgly PF00912.17 EIW72810.1 - 0.051 12.8 0.2 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Transglycosylase HAMP PF00672.20 EIW72811.1 - 2.2e-52 175.1 20.5 8.4e-09 35.4 0.1 7.9 7 1 0 7 7 7 7 HAMP domain HATPase_c PF02518.21 EIW72811.1 - 6e-28 96.7 1.4 1.4e-27 95.6 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIW72811.1 - 2.5e-25 88.6 0.3 8.8e-24 83.6 0.1 3.1 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EIW72811.1 - 3.6e-14 52.4 0.4 2.3e-13 49.9 0.3 2.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EIW72811.1 - 0.0022 17.6 0.0 0.0054 16.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Syntaxin PF00804.20 EIW72811.1 - 0.027 14.6 6.0 1.4 9.1 0.7 4.7 4 1 1 5 5 5 0 Syntaxin PilJ PF13675.1 EIW72811.1 - 0.03 14.6 0.2 35 4.7 0.0 3.9 3 1 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term SpoIIID PF12116.3 EIW72811.1 - 0.084 12.8 1.3 14 5.7 0.0 4.4 5 0 0 5 5 5 0 Stage III sporulation protein D CENP-F_leu_zip PF10473.4 EIW72811.1 - 0.15 11.8 11.9 2 8.2 1.1 5.0 5 1 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2365 PF10157.4 EIW72811.1 - 0.49 10.2 17.1 13 5.6 0.0 6.8 7 2 1 9 9 9 0 Uncharacterized conserved protein (DUF2365) Aminotran_5 PF00266.14 EIW72812.1 - 1.8e-13 49.9 0.0 8.1e-13 47.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EIW72812.1 - 0.05 11.8 0.0 0.077 11.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme FAM124 PF15067.1 EIW72813.1 - 0.029 13.7 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 FAM124 family CFEM PF05730.6 EIW72813.1 - 0.06 13.1 0.5 0.12 12.1 0.4 1.5 1 1 0 1 1 1 0 CFEM domain F-box-like PF12937.2 EIW72815.1 - 1.2e-06 28.1 0.1 2.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW72815.1 - 8.2e-05 22.1 0.2 0.0037 16.8 0.0 3.6 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIW72815.1 - 0.00018 21.2 0.2 0.26 11.4 0.0 3.9 3 0 0 3 3 3 1 Leucine Rich repeat LRR_8 PF13855.1 EIW72815.1 - 0.00041 20.0 0.6 0.025 14.3 0.0 3.1 3 0 0 3 3 3 1 Leucine rich repeat TPR_8 PF13181.1 EIW72815.1 - 0.0026 17.4 0.1 3 7.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW72815.1 - 0.0035 16.9 0.3 3.1 7.5 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW72815.1 - 0.0047 16.7 2.0 1.3 9.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat BRE1 PF08647.6 EIW72815.1 - 0.0078 16.1 2.5 0.021 14.7 1.7 1.7 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase LRR_7 PF13504.1 EIW72815.1 - 0.011 15.7 0.1 9.6 6.9 0.0 4.7 4 0 0 4 4 4 0 Leucine rich repeat TPR_11 PF13414.1 EIW72815.1 - 0.013 15.1 2.9 0.044 13.4 0.5 2.5 1 1 1 2 2 2 0 TPR repeat DNA_pol_A_exo1 PF01612.15 EIW72816.1 - 2.6e-42 144.2 0.0 3.9e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EIW72816.1 - 2.2e-13 50.2 0.0 8.9e-13 48.3 0.0 2.1 1 1 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 EIW72816.1 - 7.1e-13 48.0 0.0 2.1e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 HRDC domain CbiC PF02570.10 EIW72817.1 - 0.059 12.7 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 Precorrin-8X methylmutase DUF2615 PF11027.3 EIW72817.1 - 0.086 12.7 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) MRP-L46 PF11788.3 EIW72818.1 - 2.4e-12 47.4 0.1 4.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EIW72818.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain Gtr1_RagA PF04670.7 EIW72819.1 - 2.6e-49 167.4 0.3 3.3e-49 167.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIW72819.1 - 4.2e-06 27.2 0.1 2.2e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIW72819.1 - 0.00021 20.6 0.1 0.00041 19.6 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIW72819.1 - 0.0071 15.7 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EIW72819.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EIW72819.1 - 0.041 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain MRC1 PF09444.5 EIW72820.1 - 3.8e-12 46.7 20.4 3.8e-12 46.7 14.2 4.8 4 2 1 5 5 5 1 MRC1-like domain DUF1320 PF07030.7 EIW72822.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) Pkinase PF00069.20 EIW72823.1 - 1.3e-61 208.0 0.0 5.9e-41 140.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72823.1 - 3.1e-27 95.2 0.0 4.5e-22 78.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EIW72823.1 - 1.7e-15 57.0 0.1 4.7e-15 55.5 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.19 EIW72823.1 - 3.1e-08 33.4 0.4 9e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EIW72823.1 - 3e-06 27.5 0.0 8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain Kinase-like PF14531.1 EIW72823.1 - 0.00038 19.5 0.1 0.009 15.0 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EIW72823.1 - 0.0093 15.7 0.0 0.12 12.0 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIW72823.1 - 0.035 12.9 0.0 0.06 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_3 PF08447.6 EIW72823.1 - 0.055 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 PAS fold CLASP_N PF12348.3 EIW72825.1 - 1.6e-62 210.8 1.1 1e-44 152.6 0.1 4.7 3 1 1 4 4 4 4 CLASP N terminal HEAT PF02985.17 EIW72825.1 - 2.5e-06 27.0 2.4 0.021 14.8 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EIW72825.1 - 0.00018 21.7 1.9 0.0043 17.2 0.6 3.0 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EIW72825.1 - 0.086 13.3 4.8 0.92 10.0 0.3 3.5 3 0 0 3 3 3 0 HEAT-like repeat Pkinase PF00069.20 EIW72826.1 - 1.7e-55 188.0 0.0 3.8e-51 173.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72826.1 - 6e-32 110.7 0.0 7.5e-30 103.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PH_3 PF14593.1 EIW72826.1 - 0.00013 21.7 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 2 PH domain Kinase-like PF14531.1 EIW72826.1 - 0.00024 20.1 0.0 0.00039 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 EIW72826.1 - 0.0004 20.5 0.0 0.00096 19.3 0.0 1.6 1 0 0 1 1 1 1 PH domain APH PF01636.18 EIW72826.1 - 0.0022 17.8 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW72826.1 - 0.0033 16.5 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Barstar PF01337.13 EIW72826.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Barstar (barnase inhibitor) RIO1 PF01163.17 EIW72826.1 - 0.17 11.2 0.1 0.33 10.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 EIW72826.1 - 0.26 10.6 0.0 0.53 9.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EIW72826.1 - 0.3 9.8 0.1 0.45 9.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Flavokinase PF01687.12 EIW72827.1 - 1.4e-40 138.0 0.0 1.6e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Gly_transf_sug PF04488.10 EIW72828.1 - 3.4e-07 30.5 0.0 5.9e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIW72828.1 - 0.12 11.4 1.0 0.22 10.6 0.7 1.5 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein Porin_3 PF01459.17 EIW72829.1 - 3.9e-67 226.4 0.4 4.4e-67 226.2 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin RRM_6 PF14259.1 EIW72830.1 - 7.9e-12 44.9 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW72830.1 - 1e-11 44.2 0.0 1.6e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW72830.1 - 1.5e-06 27.9 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIW72830.1 - 0.014 15.1 0.0 0.045 13.5 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 SSB PF00436.20 EIW72831.1 - 1.1e-14 54.0 0.0 1.5e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family SNF5 PF04855.7 EIW72832.1 - 2.8e-53 180.8 1.6 4.3e-53 180.2 1.1 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 TRAP_alpha PF03896.11 EIW72832.1 - 5.7 5.8 9.3 1.5 7.7 1.7 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit OPT PF03169.10 EIW72833.1 - 1.4e-177 591.8 54.7 1.7e-177 591.6 37.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3040 PF11239.3 EIW72833.1 - 0.058 13.4 0.3 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Erg28 PF03694.8 EIW72834.1 - 3.1e-37 126.9 0.4 3.8e-37 126.6 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein ECH PF00378.15 EIW72835.1 - 3.2e-23 82.1 0.0 2.2e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Fungal_trans PF04082.13 EIW72836.1 - 6.2e-13 48.2 0.0 9.6e-13 47.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW72836.1 - 0.00022 21.0 7.9 0.00038 20.3 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CwfJ_C_1 PF04677.10 EIW72838.1 - 1.1e-31 109.0 0.0 2.4e-31 107.9 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EIW72838.1 - 2.8e-21 75.8 0.0 5.5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 EIW72838.1 - 4.9e-10 38.7 16.4 0.00012 21.4 2.1 3.9 3 0 0 3 3 3 3 Zinc knuckle Tmemb_14 PF03647.8 EIW72840.1 - 8.6e-13 48.5 5.8 9.7e-13 48.3 4.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C 2OG-FeII_Oxy_2 PF13532.1 EIW72841.1 - 6.5e-09 35.8 0.0 1.9e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp_Arg_Hydrox PF05118.10 EIW72841.1 - 0.048 13.4 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase tRNA_int_endo PF01974.12 EIW72842.1 - 1.1e-17 63.5 0.1 1.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EIW72842.1 - 3.4e-06 26.5 0.3 0.0004 19.8 0.2 2.6 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain RRM_1 PF00076.17 EIW72843.1 - 2.5e-61 203.2 0.0 1.5e-16 59.7 0.0 5.8 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW72843.1 - 5.6e-52 173.6 0.0 3e-16 59.1 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW72843.1 - 3.5e-33 113.2 0.0 1.2e-07 31.4 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIW72843.1 - 0.00011 21.8 0.3 1.8 8.3 0.0 5.3 5 2 0 5 5 5 2 Limkain b1 Smg4_UPF3 PF03467.10 EIW72843.1 - 0.086 12.8 0.4 13 5.7 0.0 2.9 3 0 0 3 3 3 0 Smg-4/UPF3 family Ribosomal_S19e PF01090.14 EIW72844.1 - 1.4e-53 180.0 0.0 1.7e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_60s PF00428.14 EIW72844.1 - 0.015 15.6 8.8 0.026 14.8 6.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 EIW72844.1 - 0.12 11.8 7.3 0.14 11.6 5.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EIW72844.1 - 1.3 8.1 5.7 1.5 7.8 4.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Flavin_Reduct PF01613.13 EIW72845.1 - 1.1e-24 87.0 0.0 1.6e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DcpS_C PF11969.3 EIW72846.1 - 2e-10 40.9 5.1 3.7e-10 40.0 3.5 1.4 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EIW72846.1 - 0.012 16.0 9.0 0.073 13.6 6.2 1.9 1 1 0 1 1 1 0 HIT domain DnaJ PF00226.26 EIW72847.1 - 7e-18 64.1 1.5 1.6e-17 62.9 1.1 1.7 1 0 0 1 1 1 1 DnaJ domain YjeF_N PF03853.10 EIW72847.1 - 0.023 14.2 1.4 0.03 13.9 0.0 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus DNA_pol3_a_NII PF11490.3 EIW72847.1 - 0.37 10.4 6.5 0.45 10.1 3.6 1.7 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II TFIIF_alpha PF05793.7 EIW72848.1 - 8.8 4.5 57.4 1.9e+03 -3.2 39.5 3.1 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L37e PF01907.14 EIW72849.1 - 2.5e-21 75.2 11.6 4.3e-21 74.4 8.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EIW72849.1 - 0.0012 18.6 2.4 0.0016 18.2 1.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 EIW72849.1 - 0.06 13.0 1.9 0.094 12.4 1.3 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EIW72849.1 - 0.17 11.8 1.9 12 5.8 0.0 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Ribosomal_S14 PF00253.16 EIW72849.1 - 0.2 11.0 0.3 0.2 11.0 0.2 2.8 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e zinc_ribbon_6 PF14599.1 EIW72849.1 - 0.26 11.0 3.3 0.38 10.5 2.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon zf-ribbon_3 PF13248.1 EIW72849.1 - 0.26 10.5 3.2 0.68 9.2 2.3 1.7 1 1 1 2 2 2 0 zinc-ribbon domain DUF35_N PF12172.3 EIW72849.1 - 0.5 10.3 3.0 0.85 9.6 2.1 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) GFA PF04828.9 EIW72849.1 - 0.52 10.2 4.5 18 5.3 2.6 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-Mss51 PF13824.1 EIW72849.1 - 0.71 9.7 4.3 1.2 9.0 3.0 1.6 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_5 PF14634.1 EIW72849.1 - 0.75 9.5 6.4 1.1 9.0 4.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_2 PF13240.1 EIW72849.1 - 1.2 8.6 5.0 22 4.6 0.2 2.3 1 1 1 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EIW72849.1 - 1.3 8.5 5.1 3.3 7.2 0.7 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C3HC4_2 PF13923.1 EIW72849.1 - 1.3 9.0 6.7 2.2 8.3 4.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_POL_M_15KD PF02150.11 EIW72849.1 - 5.4 6.7 5.6 2.4 7.9 0.3 2.1 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit PAP2 PF01569.16 EIW72850.1 - 7e-13 48.3 1.2 9.3e-13 47.9 0.4 1.4 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 EIW72850.1 - 0.1 12.3 0.3 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Divergent PAP2 family DUF3759 PF12585.3 EIW72851.1 - 3.6e-34 116.5 2.6 4.3e-34 116.3 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) CH PF00307.26 EIW72853.1 - 2.2e-42 143.4 0.0 2.8e-24 85.2 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EIW72853.1 - 5e-16 58.4 0.0 1.4e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EIW72853.1 - 8.7e-16 57.3 0.1 3e-11 42.7 0.0 3.2 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 EIW72853.1 - 0.00037 20.1 0.4 0.0025 17.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain DUF1042 PF06294.6 EIW72853.1 - 0.013 15.1 0.1 1.5 8.3 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1042) EF-hand_7 PF13499.1 EIW72853.1 - 0.072 13.2 0.2 0.33 11.1 0.1 2.2 1 1 0 1 1 1 0 EF-hand domain pair Cofilin_ADF PF00241.15 EIW72854.1 - 1.2e-36 125.3 0.0 1.3e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-AN1 PF01428.11 EIW72856.1 - 4.2e-09 36.1 6.4 8.8e-09 35.1 4.4 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger Involucrin_N PF10583.4 EIW72856.1 - 0.47 10.7 5.4 0.86 9.9 0.3 2.5 1 1 1 2 2 2 0 Involucrin of squamous epithelia N-terminus DUF3818 PF12825.2 EIW72857.1 - 9.2e-112 373.0 0.3 1.4e-111 372.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EIW72857.1 - 2.1e-25 88.9 0.2 2.1e-25 88.9 0.1 2.0 2 0 0 2 2 2 1 PX-associated PX PF00787.19 EIW72857.1 - 6.5e-14 51.6 0.1 3.8e-13 49.2 0.0 2.3 3 0 0 3 3 3 1 PX domain Clr2 PF10383.4 EIW72858.1 - 2e-06 27.8 0.0 1.3e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 F1F0-ATPsyn_F PF10791.4 EIW72859.1 - 3.6e-32 110.4 0.0 4e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi DUF3759 PF12585.3 EIW72861.1 - 1.2e-16 60.3 2.0 1.3e-16 60.2 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) GRAB PF10375.4 EIW72862.1 - 5e-07 29.0 1.3 5e-07 29.0 0.9 2.6 2 0 0 2 2 2 1 GRIP-related Arf-binding domain GRIP PF01465.15 EIW72862.1 - 0.00083 18.8 0.0 0.0021 17.5 0.0 1.7 1 0 0 1 1 1 1 GRIP domain Reo_sigmaC PF04582.7 EIW72862.1 - 0.0034 16.6 4.8 0.0034 16.6 3.3 2.2 2 0 0 2 2 2 1 Reovirus sigma C capsid protein IncA PF04156.9 EIW72862.1 - 0.0056 16.2 21.2 0.0056 16.2 14.7 4.1 1 1 3 4 4 4 2 IncA protein TPR_MLP1_2 PF07926.7 EIW72862.1 - 0.34 10.6 40.8 3.4 7.4 10.9 3.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein WEMBL PF05701.6 EIW72862.1 - 0.36 9.2 47.1 0.014 13.8 23.0 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light HrpA_pilin PF09589.5 EIW72862.1 - 1.6 9.1 7.4 7 7.1 0.7 3.1 2 1 1 3 3 3 0 HrpA pilus formation protein DUF3584 PF12128.3 EIW72862.1 - 3.4 4.8 40.2 0.71 7.1 24.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 EIW72862.1 - 3.6 7.3 9.6 0.39 10.5 2.3 2.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) ERM PF00769.14 EIW72862.1 - 4.2 6.8 46.4 1.2 8.6 26.4 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HALZ PF02183.13 EIW72862.1 - 5 6.9 19.1 6.7 6.5 0.3 5.1 3 1 1 5 5 4 0 Homeobox associated leucine zipper AAA_13 PF13166.1 EIW72862.1 - 6.8 5.0 27.0 0.31 9.4 6.4 2.2 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.6 EIW72862.1 - 7.1 5.1 35.8 0.2 10.2 12.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2730 PF10805.3 EIW72862.1 - 7.6 6.3 14.8 1.3 8.7 2.5 3.5 3 2 2 5 5 5 0 Protein of unknown function (DUF2730) ADIP PF11559.3 EIW72862.1 - 8.7 6.2 49.3 0.27 11.1 8.7 4.2 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Pho88 PF10032.4 EIW72863.1 - 5e-69 231.3 0.0 5.9e-69 231.1 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) ATP-synt_G PF04718.10 EIW72864.1 - 1.5e-15 57.7 0.0 4.1e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit B3_4 PF03483.12 EIW72865.1 - 1.7e-21 76.4 0.1 3.5e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EIW72865.1 - 8.8e-16 57.4 0.0 2.9e-13 49.4 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF3531 PF12049.3 EIW72865.1 - 0.23 11.1 0.0 0.48 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) ABC_membrane_2 PF06472.10 EIW72866.1 - 3.5e-91 305.2 0.2 5e-91 304.7 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EIW72866.1 - 7.7e-19 68.3 0.0 1.6e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW72866.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EIW72866.1 - 0.017 15.4 0.7 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EIW72866.1 - 0.027 13.6 0.0 0.18 10.9 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIW72866.1 - 0.036 13.5 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW72866.1 - 0.091 12.7 0.6 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain PH PF00169.24 EIW72867.1 - 5.1e-05 23.4 0.0 9.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 PH domain FCH PF00611.18 EIW72867.1 - 0.052 13.7 0.0 0.78 9.9 0.0 2.6 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Orthopox_A5L PF06193.6 EIW72867.1 - 0.075 12.9 1.2 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like Frag1 PF10277.4 EIW72868.1 - 1.4e-40 139.1 12.2 1.6e-40 138.8 8.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family ABC2_membrane_5 PF13346.1 EIW72868.1 - 0.065 12.5 6.6 0.041 13.1 2.1 2.3 2 1 1 3 3 3 0 ABC-2 family transporter protein Na_Ca_ex PF01699.19 EIW72868.1 - 0.13 11.8 6.8 0.033 13.7 0.7 2.3 2 1 0 2 2 2 0 Sodium/calcium exchanger protein MscS_TM PF12794.2 EIW72868.1 - 0.13 10.7 4.9 2.5 6.6 0.1 3.0 3 0 0 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 DUF1282 PF06930.7 EIW72868.1 - 0.32 10.6 4.1 0.48 10.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Na_Ca_ex PF01699.19 EIW72870.1 - 1.7e-25 89.2 29.6 1.1e-13 51.0 4.7 3.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EIW72870.1 - 8.7e-09 35.6 11.0 8.7e-09 35.6 7.7 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF307) DUF2106 PF09879.4 EIW72870.1 - 0.062 12.6 1.2 3.5 6.9 0.3 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2106) zf-PARP PF00645.13 EIW72871.1 - 2.8e-23 81.9 0.0 7.4e-23 80.6 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ABC_membrane PF00664.18 EIW72872.1 - 4.7e-67 226.3 36.9 3.6e-39 134.8 6.2 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW72872.1 - 2.5e-50 170.3 0.0 1.2e-29 103.4 0.0 3.0 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIW72872.1 - 1.2e-07 31.2 0.1 0.0052 16.0 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIW72872.1 - 2.2e-06 27.8 2.9 0.24 11.3 0.1 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 EIW72872.1 - 7e-06 26.2 0.0 0.39 10.6 0.0 4.4 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 EIW72872.1 - 0.00019 21.3 0.1 0.6 10.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EIW72872.1 - 0.0032 16.6 0.1 0.42 9.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIW72872.1 - 0.0033 16.9 2.0 2.5 7.6 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain Miro PF08477.8 EIW72872.1 - 0.0036 17.7 0.5 2.4 8.6 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 EIW72872.1 - 0.0037 16.6 0.0 1.9 7.8 0.0 2.6 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 EIW72872.1 - 0.0043 16.8 3.2 0.028 14.2 0.1 2.6 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 EIW72872.1 - 0.02 14.5 0.3 4.9 6.8 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EIW72872.1 - 0.051 12.4 0.3 1.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 EIW72872.1 - 0.19 10.4 2.0 9.5 4.9 0.1 2.5 3 0 0 3 3 3 0 ArgK protein DUF87 PF01935.12 EIW72872.1 - 0.21 11.3 9.5 0.34 10.6 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EIW72872.1 - 9 5.6 6.9 20 4.4 0.3 3.0 3 1 1 4 4 4 0 AAA-like domain DUF3253 PF11625.3 EIW72874.1 - 3.9e-19 68.3 0.0 5e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) Ribosomal_L18p PF00861.17 EIW72875.1 - 1.7e-41 141.1 0.4 3.7e-41 140.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EIW72875.1 - 1.3e-32 112.1 4.3 1.3e-32 112.1 3.0 2.1 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region Thioredoxin PF00085.15 EIW72876.1 - 1.2e-23 82.7 0.0 2.9e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EIW72876.1 - 0.00023 21.3 0.7 0.00076 19.6 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIW72876.1 - 0.0022 18.0 0.0 1.4 9.0 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Herpes_UL49_1 PF03117.9 EIW72876.1 - 0.0054 15.8 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 UL49 family Thioredoxin_7 PF13899.1 EIW72876.1 - 0.03 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Oligomerisation PF02410.10 EIW72877.1 - 0.0096 15.9 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Oligomerisation domain Thiolase_N PF00108.18 EIW72878.1 - 2.1e-91 305.6 1.1 2.7e-91 305.2 0.7 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIW72878.1 - 3.8e-43 145.8 3.8 1e-42 144.4 0.3 2.7 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIW72878.1 - 2.4e-07 30.4 3.1 6.1e-05 22.6 0.5 3.0 2 1 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 EIW72878.1 - 0.069 13.1 0.1 7 6.7 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CMD PF02627.15 EIW72878.1 - 0.091 12.6 0.2 0.95 9.3 0.0 2.5 3 0 0 3 3 3 0 Carboxymuconolactone decarboxylase family Mito_carr PF00153.22 EIW72879.1 - 9.7e-33 111.7 4.5 6.6e-15 54.5 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L14 PF00238.14 EIW72880.1 - 2.9e-40 136.8 0.9 3.3e-40 136.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e LSM PF01423.17 EIW72883.1 - 2.3e-14 52.6 0.1 3.6e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIW72883.1 - 0.04 13.8 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain S-AdoMet_synt_N PF00438.15 EIW72883.1 - 0.091 13.0 0.1 0.42 10.8 0.0 1.8 1 1 1 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain ADH_N PF08240.7 EIW72885.1 - 2.2e-24 85.2 8.3 2.2e-24 85.2 5.8 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW72885.1 - 9.6e-13 47.8 0.1 2.1e-12 46.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW72885.1 - 0.0019 19.0 0.0 0.0042 17.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIW72885.1 - 0.0039 16.3 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EIW72885.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EIW72885.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EIW72885.1 - 0.017 14.7 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EIW72885.1 - 0.072 12.7 0.5 0.77 9.3 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EIW72885.1 - 0.093 12.7 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding COX6B PF02297.12 EIW72886.1 - 4.2e-23 81.1 1.6 5.2e-23 80.8 1.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UQ_con PF00179.21 EIW72887.1 - 3.1e-41 140.0 0.0 4.1e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EIW72887.1 - 1.3e-12 47.0 0.0 2.1e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EIW72887.1 - 0.0025 17.5 0.0 0.0046 16.7 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B DUF1421 PF07223.6 EIW72887.1 - 0.035 13.9 0.1 0.049 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Calsarcin PF05556.6 EIW72887.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) tRNA_m1G_MT PF01746.16 EIW72888.1 - 9.2e-32 110.1 0.1 4.3e-27 94.9 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase zf-HC2 PF13490.1 EIW72888.1 - 0.063 13.2 0.0 0.27 11.2 0.0 2.1 1 0 0 1 1 1 0 Putative zinc-finger DUF3847 PF12958.2 EIW72888.1 - 2.6 7.8 8.2 2.4 7.9 3.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3847) Sin3_corepress PF08295.7 EIW72890.1 - 1.2e-37 127.7 0.2 4.5e-37 125.8 0.2 2.1 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 EIW72890.1 - 1e-33 114.6 0.7 9.4e-16 57.1 0.9 2.6 2 0 0 2 2 2 2 Paired amphipathic helix repeat HMGL-like PF00682.14 EIW72891.1 - 3.7e-30 105.3 0.0 9.7e-30 103.9 0.0 1.6 1 1 0 1 1 1 1 HMGL-like WD40 PF00400.27 EIW72892.1 - 1.6e-83 271.8 22.8 9.2e-09 34.8 0.0 11.7 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 EIW72892.1 - 7.3e-40 135.8 0.1 1.4e-39 134.9 0.1 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain VID27 PF08553.5 EIW72892.1 - 0.0012 17.2 0.0 0.013 13.7 0.0 2.1 2 0 0 2 2 2 1 VID27 cytoplasmic protein Arena_nucleocap PF00843.12 EIW72892.1 - 0.0058 14.5 0.8 0.55 8.0 0.1 2.3 2 0 0 2 2 2 2 Arenavirus nucleocapsid protein FH2 PF02181.18 EIW72893.1 - 0.0078 15.1 1.8 0.0078 15.1 1.3 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Spc24 PF08286.6 EIW72893.1 - 0.31 10.7 7.7 0.22 11.2 0.3 2.9 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 IncA PF04156.9 EIW72893.1 - 2.3 7.7 16.5 2.2 7.8 3.3 2.4 2 0 0 2 2 2 0 IncA protein Uds1 PF15456.1 EIW72893.1 - 4 7.4 10.9 20 5.2 0.1 2.6 2 0 0 2 2 2 0 Up-regulated During Septation RRM_1 PF00076.17 EIW72894.1 - 9.8e-18 63.5 0.0 1.2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW72894.1 - 3e-12 46.3 0.0 3.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW72894.1 - 1.8e-05 24.5 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIW72894.1 - 0.0015 18.3 0.0 0.0018 18.0 0.0 1.3 1 1 0 1 1 1 1 RNA binding motif PHD PF00628.24 EIW72895.1 - 4.7e-08 32.5 13.0 7.9e-08 31.8 9.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EIW72895.1 - 0.028 14.5 3.2 0.065 13.3 2.2 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 EIW72895.1 - 0.21 11.3 7.8 0.51 10.1 5.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 EIW72895.1 - 1.3 8.7 9.9 0.17 11.6 3.7 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rad60-SLD PF11976.3 EIW72896.1 - 1.1e-17 63.4 0.0 1.3e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIW72896.1 - 1.9e-06 27.1 0.0 2.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Glyco_hydro_65C PF03633.10 EIW72896.1 - 0.047 13.7 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, C-terminal domain Bac_luciferase PF00296.15 EIW72896.1 - 0.086 11.9 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase FAP PF07174.6 EIW72896.1 - 0.13 11.5 1.8 10 5.2 1.9 2.0 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) CTP_synth_N PF06418.9 EIW72898.1 - 5.6e-115 383.1 0.1 7.5e-115 382.7 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EIW72898.1 - 2e-52 177.4 0.0 3.1e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.18 EIW72898.1 - 0.0013 18.2 0.0 0.0033 16.8 0.0 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.8 EIW72898.1 - 0.0013 18.2 0.0 0.003 17.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 HTH_20 PF12840.2 EIW72899.1 - 0.063 13.0 0.0 0.17 11.6 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain B-block_TFIIIC PF04182.7 EIW72900.1 - 3.5e-09 36.3 0.3 4.4e-08 32.8 0.0 2.7 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_24 PF13412.1 EIW72900.1 - 0.0035 16.6 0.0 0.97 8.8 0.0 2.6 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding DUF2077 PF09850.4 EIW72900.1 - 0.093 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) HEAT_EZ PF13513.1 EIW72902.1 - 6.3e-06 26.5 1.7 0.1 13.1 0.0 4.9 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 EIW72902.1 - 5.1e-05 23.4 3.3 0.34 11.2 0.1 4.7 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.17 EIW72902.1 - 0.0033 17.3 10.4 2.6 8.3 0.1 6.9 7 0 0 7 7 7 2 HEAT repeat adh_short_C2 PF13561.1 EIW72903.1 - 5.8e-31 108.1 0.0 7.2e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW72903.1 - 2.7e-27 95.7 0.1 4.2e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW72903.1 - 9.3e-13 48.2 0.0 1.5e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIW72903.1 - 0.089 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pex14_N PF04695.8 EIW72904.1 - 0.65 10.0 3.0 1.2 9.1 2.1 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CN_hydrolase PF00795.17 EIW72905.1 - 1.5e-27 96.1 0.0 1.8e-26 92.6 0.0 2.0 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase CRA PF06589.6 EIW72906.1 - 0.15 11.3 0.2 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Zip PF02535.17 EIW72907.1 - 6.1e-57 193.0 15.3 4.9e-56 190.0 10.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter FtsX PF02687.16 EIW72907.1 - 7.1 6.4 8.6 0.44 10.3 1.2 2.4 2 2 0 2 2 2 0 FtsX-like permease family MULE PF10551.4 EIW72909.1 - 2.6e-13 49.9 1.4 1.1e-10 41.5 0.2 3.6 2 1 0 2 2 2 1 MULE transposase domain UCH PF00443.24 EIW72909.1 - 2.1e-09 36.9 0.0 5.1e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW72909.1 - 0.036 13.5 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.17 EIW72912.1 - 2.8e-13 49.2 0.0 9.7e-13 47.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW72912.1 - 1.7e-10 40.7 0.0 4.4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW72912.1 - 6.3e-09 35.5 0.1 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2-Hacid_dh PF00389.25 EIW72912.1 - 0.0081 15.6 1.5 0.075 12.4 0.3 2.6 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF883 PF05957.8 EIW72912.1 - 0.49 10.8 59.2 1.7 9.0 0.8 7.9 2 1 6 8 8 8 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.5 EIW72912.1 - 0.54 10.1 18.3 18 5.3 0.0 7.0 5 2 1 7 7 7 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) zf-DHHC PF01529.15 EIW72914.1 - 1.9e-33 115.2 1.5 4.2e-33 114.1 1.0 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase PgaD PF13994.1 EIW72914.1 - 0.074 12.5 1.3 0.14 11.6 0.9 1.4 1 0 0 1 1 1 0 PgaD-like protein NTF2 PF02136.15 EIW72915.1 - 7e-07 29.6 0.0 1.4e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EIW72915.1 - 0.00041 20.1 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 AMP-binding PF00501.23 EIW72916.1 - 1.5e-73 247.6 0.4 2.3e-73 246.9 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme COMP PF11598.3 EIW72917.1 - 0.00092 19.2 2.9 0.0014 18.6 2.0 1.2 1 0 0 1 1 1 1 Cartilage oligomeric matrix protein DUF106 PF01956.11 EIW72917.1 - 0.043 13.3 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 HABP4_PAI-RBP1 PF04774.10 EIW72919.1 - 2e-05 25.0 2.8 4.1e-05 24.0 2.0 1.7 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Pkinase PF00069.20 EIW72920.1 - 7.2e-64 215.4 0.0 8.3e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW72920.1 - 1.5e-24 86.4 0.0 2e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW72920.1 - 7.3e-05 21.8 0.0 0.00018 20.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIW72920.1 - 0.07 12.8 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 EIW72921.1 - 5.4e-33 111.6 23.4 6.6e-06 25.8 0.0 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EIW72921.1 - 1.2e-10 40.9 0.9 3.9e-10 39.3 0.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW72921.1 - 4.1e-08 32.6 2.3 4.1e-08 32.6 1.6 1.9 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EIW72921.1 - 7.7e-06 24.3 0.1 0.044 11.9 0.0 2.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Docking PF08990.6 EIW72922.1 - 1.1 8.5 0.0 1.1 8.5 0.0 3.6 4 0 0 4 4 4 0 Erythronolide synthase docking PRCC PF10253.4 EIW72923.1 - 4.2e-23 82.9 2.7 3.8e-22 79.8 1.9 2.4 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting GerE PF00196.14 EIW72924.1 - 0.018 14.3 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family ETF_QO PF05187.8 EIW72925.1 - 2.6e-37 127.1 0.0 4.3e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EIW72925.1 - 1.6e-07 30.5 0.7 0.00024 20.1 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW72925.1 - 2.7e-06 27.4 0.0 5.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW72925.1 - 5.7e-06 25.4 0.7 0.0013 17.6 1.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIW72925.1 - 4.6e-05 23.3 0.5 0.00021 21.2 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW72925.1 - 0.00015 20.9 0.1 0.0013 17.9 0.2 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EIW72925.1 - 0.00018 20.7 0.5 0.00038 19.6 0.3 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EIW72925.1 - 0.0014 18.4 0.4 0.0032 17.2 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIW72925.1 - 0.0016 17.4 0.3 0.0023 16.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EIW72925.1 - 0.0029 16.1 0.3 0.0042 15.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Fer4_7 PF12838.2 EIW72925.1 - 0.011 16.1 1.3 0.028 14.8 0.9 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 EIW72925.1 - 0.011 15.5 1.1 0.019 14.7 0.7 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain FAD_oxidored PF12831.2 EIW72925.1 - 0.013 14.5 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW72925.1 - 0.031 14.3 0.2 0.061 13.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.2 EIW72925.1 - 0.036 13.9 0.8 0.097 12.6 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Trp_halogenase PF04820.9 EIW72925.1 - 0.037 12.6 0.5 0.065 11.8 0.2 1.5 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EIW72925.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_6 PF12837.2 EIW72925.1 - 6.6 6.7 6.2 0.98 9.4 0.9 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Coiled-coil_56 PF09813.4 EIW72926.1 - 0.0016 18.4 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Snf7 PF03357.16 EIW72927.1 - 1.7e-21 76.3 11.0 1.9e-21 76.1 7.6 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EIW72927.1 - 0.00074 18.9 1.6 0.0011 18.4 1.1 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway GGDN PF05165.7 EIW72927.1 - 0.0067 15.4 1.4 0.011 14.7 0.6 1.5 1 1 0 1 1 1 1 GGDN family FAM117 PF15388.1 EIW72927.1 - 0.008 15.4 0.3 0.011 15.0 0.2 1.2 1 0 0 1 1 1 1 Protein Family FAM117 SYCE1 PF15233.1 EIW72927.1 - 0.096 12.6 5.5 0.12 12.2 2.9 1.9 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DASH_Spc34 PF08657.5 EIW72927.1 - 0.1 12.2 2.8 0.13 11.9 1.9 1.3 1 1 0 1 1 1 0 DASH complex subunit Spc34 Prominin PF05478.6 EIW72927.1 - 0.49 7.8 5.3 0.18 9.3 1.6 1.5 1 1 1 2 2 2 0 Prominin T2SM PF04612.7 EIW72927.1 - 1.9 8.2 6.4 1.5 8.6 0.0 2.5 2 2 0 2 2 2 0 Type II secretion system (T2SS), protein M MULE PF10551.4 EIW72929.1 - 2.3e-13 50.1 1.4 1e-10 41.5 0.2 3.6 2 1 0 2 2 2 1 MULE transposase domain UCH PF00443.24 EIW72929.1 - 2.4e-09 36.6 0.0 4.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW72929.1 - 0.034 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Erv26 PF04148.8 EIW72930.1 - 5.9e-68 228.4 8.6 6.8e-68 228.1 5.9 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2909 PF11137.3 EIW72930.1 - 0.0034 17.0 2.3 0.0045 16.6 0.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2909) Acetyltransf_1 PF00583.19 EIW72931.1 - 1e-14 54.3 0.0 1.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIW72931.1 - 7.7e-09 35.2 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIW72931.1 - 5e-08 33.0 0.0 6.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW72931.1 - 2.5e-07 30.6 0.0 2.6e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW72931.1 - 6.1e-06 26.3 0.0 9.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW72931.1 - 0.00019 21.5 0.0 0.00022 21.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW72931.1 - 0.00071 19.4 0.0 0.00088 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 EIW72931.1 - 0.028 13.2 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_CG PF14542.1 EIW72931.1 - 0.048 13.5 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 EIW72931.1 - 0.073 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF1681 PF07933.9 EIW72933.1 - 8e-57 191.2 0.0 9.4e-57 191.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Gln-synt_C PF00120.19 EIW72935.1 - 8e-59 198.8 0.0 9.5e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EIW72935.1 - 2.6e-20 71.8 0.0 4.3e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4098 PF13345.1 EIW72936.1 - 1.5e-06 28.0 0.7 0.0018 18.2 0.1 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4098) Lipase_GDSL PF00657.17 EIW72937.1 - 1.6e-11 44.4 0.0 6e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIW72937.1 - 1.2e-09 38.6 0.5 4.2e-09 36.7 0.3 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF2772 PF10970.3 EIW72940.1 - 0.034 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2772) Propeptide_C1 PF08127.8 EIW72940.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C1 propeptide Metallophos PF00149.23 EIW72941.1 - 4.2e-43 147.0 0.5 5.4e-43 146.7 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rootletin PF15035.1 EIW72942.1 - 0.023 14.6 2.4 0.18 11.7 0.1 2.7 2 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Dehydratase_MU PF02288.10 EIW72942.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Dehydratase medium subunit CorA PF01544.13 EIW72942.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TBPIP PF07106.8 EIW72942.1 - 0.23 11.0 1.5 3.3 7.2 0.0 2.5 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SUR7 PF06687.7 EIW72943.1 - 0.00033 20.2 4.2 0.00061 19.4 0.0 2.1 1 1 0 2 2 2 1 SUR7/PalI family CRAL_TRIO PF00650.15 EIW72945.1 - 3.4e-14 52.6 0.0 5.5e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain MFS_2 PF13347.1 EIW72946.1 - 2.9e-08 32.5 1.9 2.9e-08 32.5 1.3 2.7 3 0 0 3 3 3 1 MFS/sugar transport protein DUF898 PF05987.8 EIW72946.1 - 0.0049 15.8 0.0 0.0049 15.8 0.0 3.4 4 0 0 4 4 4 1 Bacterial protein of unknown function (DUF898) Corona_nucleoca PF00937.13 EIW72946.1 - 0.099 11.5 3.1 0.17 10.7 2.2 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DnaJ PF00226.26 EIW72947.1 - 9.9e-26 89.2 1.8 1.6e-25 88.6 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIW72947.1 - 6.1e-20 70.9 0.1 5.2e-18 64.7 0.0 2.9 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIW72947.1 - 1e-15 57.5 17.6 1.9e-15 56.6 12.2 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EIW72947.1 - 0.00076 19.1 4.6 0.013 15.1 0.1 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EIW72947.1 - 0.045 13.5 9.6 0.12 12.2 6.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon Cytochrom_c3_2 PF14537.1 EIW72947.1 - 0.089 13.1 8.6 0.22 11.8 6.0 1.7 1 1 0 1 1 1 0 Cytochrome c3 DegS PF05384.6 EIW72947.1 - 0.15 11.2 0.4 0.43 9.7 0.2 1.7 1 1 1 2 2 2 0 Sensor protein DegS A2L_zn_ribbon PF08792.5 EIW72947.1 - 0.24 10.8 13.1 0.56 9.7 0.3 3.8 3 1 1 4 4 4 0 A2L zinc ribbon domain PAAR_motif PF05488.8 EIW72947.1 - 5.1 7.1 9.9 1.2 9.1 0.5 3.2 1 1 1 2 2 2 0 PAAR motif Lar_restr_allev PF14354.1 EIW72947.1 - 6 7.2 7.9 1.2e+02 3.1 5.5 2.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar Ofd1_CTDD PF10637.4 EIW72950.1 - 2.4e-77 259.6 0.0 4.2e-74 249.0 0.0 2.6 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EIW72950.1 - 2.3e-11 44.1 0.4 5e-10 39.7 0.3 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 23S_rRNA_IVP PF05635.6 EIW72951.1 - 0.017 15.0 0.2 0.032 14.1 0.2 1.4 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein Hid1 PF12722.2 EIW72951.1 - 1.5 6.3 6.2 2.1 5.9 4.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRM_1 PF00076.17 EIW72953.1 - 2.4e-45 152.0 0.0 8.1e-23 79.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW72953.1 - 1.3e-33 114.8 0.0 8.3e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW72953.1 - 4.5e-21 74.4 0.0 1.1e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW72953.1 - 0.00022 20.9 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EIW72953.1 - 4.9 5.4 43.5 6.5 5.1 30.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Iso_dh PF00180.15 EIW72954.1 - 1.1e-93 314.0 0.0 1.3e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FAD_binding_3 PF01494.14 EIW72956.1 - 8.1e-12 44.8 0.0 6.2e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIW72956.1 - 0.015 15.3 0.4 0.042 13.8 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SE PF08491.5 EIW72956.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyridoxal_deC PF00282.14 EIW72957.1 - 2.6e-64 217.0 0.0 3.3e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EIW72957.1 - 0.00029 19.6 0.0 0.00045 19.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF1996 PF09362.5 EIW72958.1 - 5.9e-75 251.9 1.4 9e-75 251.3 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EIW72958.1 - 3.4e-34 116.6 37.3 2.7e-17 62.4 7.5 2.9 3 0 0 3 3 3 2 WSC domain Kelch_6 PF13964.1 EIW72958.1 - 2 8.7 6.9 8.6 6.7 0.2 3.2 2 1 0 2 2 2 0 Kelch motif WSC PF01822.14 EIW72959.1 - 7.4e-29 99.5 31.2 1.2e-16 60.4 9.0 3.2 3 1 0 3 3 3 2 WSC domain GP4 PF03010.9 EIW72960.1 - 0.21 11.1 1.8 0.36 10.4 1.2 1.3 1 0 0 1 1 1 0 GP4 Pro_isomerase PF00160.16 EIW72961.1 - 2.4e-38 131.7 0.0 3.9e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EIW72961.1 - 2.5e-16 59.0 0.0 5.4e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW72961.1 - 1.7e-12 47.1 0.0 4.1e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW72961.1 - 1.3e-08 34.5 0.0 3.4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EIW72961.1 - 4.9 5.4 18.5 7.3 4.9 12.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3072 PF11272.3 EIW72962.1 - 1.4e-19 69.4 0.0 1.1e-10 40.9 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3072) DUF605 PF04652.11 EIW72962.1 - 0.21 10.9 16.6 0.35 10.2 11.5 1.4 1 0 0 1 1 1 0 Vta1 like Anoctamin PF04547.7 EIW72964.1 - 9.9e-90 301.3 0.0 1.3e-89 300.9 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel RVT_1 PF00078.22 EIW72965.1 - 1e-21 77.3 0.2 3.2e-21 75.6 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIW72965.1 - 2.2e-18 66.4 0.0 6.4e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIW72965.1 - 5e-08 32.4 0.1 1.5e-07 30.9 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 EIW72965.1 - 2.2e-06 28.0 0.2 7.1e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease Retrotrans_gag PF03732.12 EIW72965.1 - 2.6e-06 27.3 0.0 1.2e-05 25.2 0.0 2.2 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 EIW72965.1 - 2.9e-06 26.9 0.0 6.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EIW72965.1 - 0.002 18.0 0.0 0.0074 16.2 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP PF00077.15 EIW72965.1 - 0.0032 17.3 0.0 0.0082 16.0 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3818 PF12825.2 EIW72965.1 - 0.19 10.4 0.0 0.34 9.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Asp_protease PF09668.5 EIW72965.1 - 0.23 11.0 0.0 0.58 9.7 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease PP2C PF00481.16 EIW72968.1 - 5.4e-65 219.2 0.3 5.6e-50 170.1 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Fe-S_biosyn PF01521.15 EIW72969.1 - 2.2e-09 37.2 0.0 2.8e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Histone PF00125.19 EIW72970.1 - 4e-14 52.4 0.1 4.9e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW72970.1 - 3.7e-05 23.8 0.0 4.9e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIW72970.1 - 0.00011 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIW72970.1 - 0.0012 18.8 0.1 0.0025 17.8 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIW72970.1 - 0.046 12.9 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T VWA_2 PF13519.1 EIW72971.1 - 1.6e-15 57.5 2.0 3.3e-15 56.6 0.0 2.0 2 1 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.9 EIW72971.1 - 2.9e-10 40.0 0.0 5.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EIW72971.1 - 1.4e-06 27.3 22.3 0.035 13.6 0.7 4.1 3 1 0 3 3 3 3 Ubiquitin interaction motif VWA PF00092.23 EIW72971.1 - 1.4e-06 28.1 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain FAA_hydrolase PF01557.13 EIW72971.1 - 0.0054 16.2 0.2 0.018 14.5 0.1 1.8 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Actin PF00022.14 EIW72972.1 - 2.8e-159 529.7 0.0 3.2e-159 529.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EIW72972.1 - 0.078 13.3 0.1 0.22 11.9 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Methyltransf_29 PF03141.11 EIW72972.1 - 0.14 10.4 0.0 0.21 9.8 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase WD40 PF00400.27 EIW72973.1 - 4.5e-18 64.3 9.3 3.7e-08 32.9 0.7 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIW72973.1 - 0.018 14.8 0.0 4.1 7.2 0.0 3.6 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Mito_carr PF00153.22 EIW72975.1 - 2.8e-66 219.2 2.9 1.1e-21 76.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Toxin_52 PF15605.1 EIW72976.1 - 0.0059 16.4 1.9 0.0072 16.1 1.3 1.1 1 0 0 1 1 1 1 Putative toxin 52 CRF PF00473.12 EIW72976.1 - 0.06 13.4 1.1 0.06 13.4 0.7 2.2 2 0 0 2 2 2 0 Corticotropin-releasing factor family AATF-Che1 PF13339.1 EIW72976.1 - 0.11 12.6 6.7 0.17 12.0 4.6 1.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF883 PF05957.8 EIW72976.1 - 0.11 12.8 6.4 0.053 13.9 1.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Adaptin_binding PF10199.4 EIW72976.1 - 0.13 12.5 8.9 0.16 12.2 6.2 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF2514 PF10721.4 EIW72976.1 - 1.6 8.4 11.4 2 8.1 7.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Nefa_Nip30_N PF10187.4 EIW72976.1 - 6.6 6.9 14.3 1.1 9.4 6.7 1.8 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Cgr1 PF03879.9 EIW72976.1 - 6.6 6.9 17.1 7.3 6.8 11.0 1.6 1 1 1 2 2 2 0 Cgr1 family RRM_1 PF00076.17 EIW72977.1 - 2.8e-08 33.2 0.0 4.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW72977.1 - 1.5e-06 28.1 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW72977.1 - 1.8e-06 27.6 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW72977.1 - 0.04 13.6 0.3 0.082 12.6 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Thiolase_N PF00108.18 EIW72979.1 - 6.9e-88 294.0 1.9 6.9e-88 294.0 1.3 1.9 2 1 1 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIW72979.1 - 2.8e-44 149.4 0.7 6.6e-44 148.2 0.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIW72979.1 - 0.0027 17.2 0.2 0.0027 17.2 0.1 3.5 4 1 1 5 5 5 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 EIW72979.1 - 0.012 15.5 0.1 0.065 13.2 0.1 2.3 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EIW72979.1 - 0.098 12.3 0.7 19 5.0 0.1 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Med17 PF10156.4 EIW72980.1 - 1.7e-46 158.5 0.0 2.2e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ECM11 PF15463.1 EIW72980.1 - 0.05 13.8 0.2 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Extracellular mutant protein 11 XAP5 PF04921.9 EIW72981.1 - 0.022 14.3 0.0 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 XAP5, circadian clock regulator Ribosomal_L16 PF00252.13 EIW72983.1 - 2.1e-38 131.0 0.3 2.6e-38 130.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF2611 PF11022.3 EIW72984.1 - 0.00018 21.4 1.8 0.0014 18.6 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2611) Claudin_2 PF13903.1 EIW72984.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3481 PF11980.3 EIW72984.1 - 0.17 11.7 0.5 0.3 10.9 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3481) NIF PF03031.13 EIW72985.1 - 1.6e-37 128.5 0.0 2.7e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Trichoplein PF13868.1 EIW72985.1 - 0.00053 18.4 3.9 0.00099 17.5 2.7 1.3 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin Remorin_C PF03763.8 EIW72985.1 - 0.028 13.9 2.3 0.092 12.2 0.3 2.1 2 0 0 2 2 2 0 Remorin, C-terminal region DnaJ PF00226.26 EIW72986.1 - 8e-18 63.9 1.5 9.5e-18 63.7 0.3 1.7 2 1 0 2 2 2 1 DnaJ domain zf-CSL PF05207.8 EIW72986.1 - 2.8e-15 55.5 1.2 4.2e-15 54.9 0.8 1.2 1 0 0 1 1 1 1 CSL zinc finger DLIC PF05783.6 EIW72988.1 - 1.4e-40 139.4 0.1 7.2e-28 97.4 0.0 3.6 3 1 1 4 4 4 3 Dynein light intermediate chain (DLIC) MFS_1 PF07690.11 EIW72989.1 - 3.8e-10 39.0 45.3 1.5e-06 27.1 14.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily KLRAQ PF10205.4 EIW72990.1 - 0.0083 16.1 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein FlgN PF05130.7 EIW72990.1 - 0.027 14.7 0.0 0.029 14.6 0.0 1.1 1 0 0 1 1 1 0 FlgN protein C2 PF00168.25 EIW72992.1 - 3.6e-19 68.4 0.0 7.8e-14 51.2 0.0 2.6 2 0 0 2 2 2 2 C2 domain Trp_repressor PF01371.14 EIW72993.1 - 0.019 14.8 0.2 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein Mss4 PF04421.8 EIW72994.1 - 1.7e-09 37.4 0.1 4.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Mss4 protein SHR3_chaperone PF08229.6 EIW72996.1 - 7.3e-29 100.1 0.1 8.8e-29 99.8 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 Vps5 PF09325.5 EIW72997.1 - 2e-18 66.5 2.2 3e-18 65.9 1.5 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EIW72997.1 - 4e-06 26.6 0.1 7.2e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 PX domain MHCassoc_trimer PF08831.5 EIW72997.1 - 0.14 12.0 0.1 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Thiolase_N PF00108.18 EIW72998.1 - 7.2e-76 254.6 0.0 1e-75 254.1 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIW72998.1 - 2.1e-45 153.1 0.2 5.2e-45 151.8 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIW72998.1 - 1.7e-05 24.4 0.3 3.2e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Myb_DNA-binding PF00249.26 EIW72999.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW72999.1 - 0.00016 21.6 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cul7 PF11515.3 EIW72999.1 - 0.021 14.7 0.2 0.034 14.0 0.2 1.2 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 MADF_DNA_bdg PF10545.4 EIW72999.1 - 0.15 12.2 0.6 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Ribosomal_L4 PF00573.17 EIW72999.1 - 0.23 10.8 1.4 0.3 10.4 1.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Prefoldin_2 PF01920.15 EIW73000.1 - 2.5e-20 72.2 0.1 3.1e-20 71.9 0.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit MtrB PF05440.7 EIW73000.1 - 0.0097 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase subunit B Prefoldin PF02996.12 EIW73000.1 - 0.04 13.5 1.6 1.9 8.1 0.2 2.0 1 1 1 2 2 2 0 Prefoldin subunit STAT_alpha PF01017.15 EIW73000.1 - 0.051 13.2 0.1 0.066 12.9 0.1 1.3 1 1 0 1 1 1 0 STAT protein, all-alpha domain DASH_Dad3 PF08656.5 EIW73000.1 - 0.063 12.9 0.3 0.52 10.0 0.1 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 DASH_Dad2 PF08654.5 EIW73000.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 FlxA PF14282.1 EIW73000.1 - 0.15 12.0 0.4 6.3 6.7 0.1 2.0 2 0 0 2 2 2 0 FlxA-like protein PCI PF01399.22 EIW73001.1 - 3.3e-10 40.2 0.1 1.1e-09 38.5 0.1 2.1 1 1 0 1 1 1 1 PCI domain DPBB_1 PF03330.13 EIW73002.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF2587 PF10759.4 EIW73008.1 - 0.042 13.2 0.1 0.12 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) zf-CCHC PF00098.18 EIW73009.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW73009.1 - 0.33 11.1 8.4 0.087 13.0 3.7 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW73009.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2587 PF10759.4 EIW73012.1 - 0.043 13.2 0.1 0.12 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PepSY_2 PF13670.1 EIW73012.1 - 0.14 12.0 0.1 0.14 12.0 0.0 2.6 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain Nop14 PF04147.7 EIW73012.1 - 0.14 10.0 0.7 0.21 9.4 0.5 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.22 EIW73013.1 - 1.4e-12 47.4 0.0 2.2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1275 PF06912.6 EIW73015.1 - 6e-17 61.5 12.4 7.7e-17 61.1 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Acyl_transf_3 PF01757.17 EIW73015.1 - 0.075 11.8 7.6 0.27 10.0 4.5 2.0 1 1 0 1 1 1 0 Acyltransferase family AAA_11 PF13086.1 EIW73016.1 - 7.2e-27 94.4 0.1 1.2e-14 54.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.1 EIW73016.1 - 5.2e-23 81.4 0.0 1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW73016.1 - 4.8e-09 35.8 0.0 1.4e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIW73016.1 - 6.7e-08 32.3 0.0 1.6e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EIW73016.1 - 0.00014 21.0 0.1 0.003 16.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 EIW73016.1 - 0.00088 19.3 0.0 0.0025 17.9 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EIW73016.1 - 0.00092 18.7 0.0 0.29 10.6 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EIW73016.1 - 0.012 15.4 0.1 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EIW73016.1 - 0.047 12.7 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA PF00004.24 EIW73016.1 - 0.11 12.6 0.3 3.9 7.6 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DSPn PF14671.1 EIW73017.1 - 1.3e-25 89.9 0.0 4.1e-24 85.1 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EIW73017.1 - 2e-15 56.5 0.0 3.3e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW73017.1 - 1e-06 28.2 0.1 2.2e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIW73017.1 - 4e-05 23.6 0.1 6.3e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EIW73017.1 - 0.0045 17.2 0.0 0.007 16.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 EIW73017.1 - 0.01 15.2 0.0 0.022 14.2 0.0 1.5 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.8 EIW73017.1 - 0.088 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Nop53 PF07767.6 EIW73019.1 - 6.6e-83 278.8 9.4 8.5e-83 278.4 6.5 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4391 PF14335.1 EIW73019.1 - 0.11 11.8 6.0 0.2 10.9 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DAP3 PF10236.4 EIW73020.1 - 6e-51 173.2 0.0 1.3e-50 172.0 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EIW73020.1 - 2.5e-06 27.5 0.2 4.2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW73020.1 - 0.0021 18.1 0.0 0.0054 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EIW73020.1 - 0.12 12.4 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Malate_synthase PF01274.17 EIW73021.1 - 9.8e-200 663.9 0.0 1.2e-199 663.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase T2SM PF04612.7 EIW73022.1 - 0.0015 18.3 0.0 0.0015 18.3 0.0 2.3 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein M ATG22 PF11700.3 EIW73022.1 - 0.39 9.1 0.0 0.6 8.5 0.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF202 PF02656.10 EIW73023.1 - 8.2e-13 48.3 3.2 8.3e-13 48.3 1.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1467 PF07330.7 EIW73023.1 - 0.26 11.0 2.5 6.9 6.5 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1467) DUF4234 PF14018.1 EIW73023.1 - 0.38 10.5 2.6 0.14 11.8 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Abhydrolase_3 PF07859.8 EIW73025.1 - 7.1e-24 84.5 0.0 2.5e-20 72.9 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW73025.1 - 2.6e-10 39.8 0.0 0.00019 20.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW73025.1 - 3.9e-10 39.6 0.0 6.7e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EIW73025.1 - 5.8e-07 28.6 1.9 1.2e-06 27.5 1.3 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EIW73025.1 - 9.2e-07 28.9 0.1 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3034 PF11231.3 EIW73025.1 - 0.0078 15.6 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3034) Esterase_phd PF10503.4 EIW73025.1 - 0.0089 15.2 0.1 1.2 8.3 0.1 2.3 2 1 0 2 2 2 2 Esterase PHB depolymerase DUF2424 PF10340.4 EIW73025.1 - 0.0093 14.6 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Sugar_tr PF00083.19 EIW73027.1 - 1.9e-66 224.5 26.1 2.2e-66 224.3 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW73027.1 - 1.8e-29 102.5 42.5 4.6e-25 88.0 15.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW73027.1 - 0.00024 19.4 0.1 0.00024 19.4 0.1 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Profilin PF00235.14 EIW73028.1 - 1.5e-36 125.1 0.1 1.6e-36 125.0 0.1 1.0 1 0 0 1 1 1 1 Profilin WD40 PF00400.27 EIW73029.1 - 8e-35 117.4 13.1 4.3e-07 29.5 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Spc7_N PF15402.1 EIW73030.1 - 1 7.2 39.2 0.02 12.9 17.8 2.1 2 0 0 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 SUR7 PF06687.7 EIW73033.1 - 8.4e-21 74.5 17.7 1.2e-20 73.9 12.3 1.3 1 0 0 1 1 1 1 SUR7/PalI family Phage_tail PF04630.7 EIW73033.1 - 0.092 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Phage major tail protein Trp_oprn_chp PF09534.5 EIW73033.1 - 0.44 10.1 3.8 0.29 10.7 0.5 2.2 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PsaL PF02605.10 EIW73033.1 - 0.47 9.9 3.3 0.67 9.4 0.7 2.1 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI Claudin_2 PF13903.1 EIW73033.1 - 4.7 6.8 23.5 4.3 7.0 13.2 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Tmemb_18A PF09771.4 EIW73033.1 - 7.1 6.6 6.6 0.43 10.5 0.9 1.7 2 0 0 2 2 2 0 Transmembrane protein 188 VIT1 PF01988.14 EIW73033.1 - 9 5.7 18.0 0.065 12.7 6.5 1.7 2 1 0 2 2 2 0 VIT family Chitin_synth_2 PF03142.10 EIW73034.1 - 3.6e-232 771.4 0.5 5.2e-232 770.9 0.4 1.2 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.23 EIW73034.1 - 1.6e-19 69.5 0.0 2.3e-12 46.5 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EIW73034.1 - 2.3e-15 56.8 2.0 2.3e-15 56.8 1.4 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW73034.1 - 4.1e-15 56.2 0.0 3.3e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 EIW73034.1 - 1.3e-11 44.1 0.0 4.4e-10 39.1 0.0 2.7 3 0 0 3 3 3 1 DEK C terminal domain Glycos_transf_2 PF00535.21 EIW73034.1 - 2.2e-06 27.4 0.0 0.0032 17.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIW73034.1 - 0.0035 16.6 0.0 0.066 12.4 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Nipped-B_C PF12830.2 EIW73035.1 - 2.4e-32 112.1 2.0 8.9e-26 90.6 0.1 2.8 1 1 1 2 2 2 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EIW73035.1 - 4.9e-12 45.5 5.7 2.6e-11 43.2 0.3 3.9 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EIW73035.1 - 0.00036 20.3 0.1 1.1 9.4 0.0 4.5 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 EIW73035.1 - 0.0011 19.2 3.5 0.13 12.6 0.2 4.9 3 1 2 5 5 5 1 HEAT repeats Cnd1 PF12717.2 EIW73035.1 - 0.0021 17.9 0.1 0.0099 15.7 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DUF883 PF05957.8 EIW73035.1 - 0.054 13.9 4.1 0.2 12.0 0.1 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Hexapep PF00132.19 EIW73036.1 - 1.5e-13 49.5 0.7 3.3e-05 23.1 0.1 4.1 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) W2 PF02020.13 EIW73036.1 - 6.9e-09 35.5 1.2 6.9e-09 35.5 0.8 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transf_3 PF12804.2 EIW73036.1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EIW73036.1 - 0.00023 20.6 2.7 0.12 11.9 0.1 3.0 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EIW73036.1 - 0.00083 18.0 0.0 0.0014 17.2 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.18 EIW73036.1 - 0.0036 16.6 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Nucleoplasmin PF03066.10 EIW73036.1 - 3.1 7.3 12.9 14 5.1 0.3 3.2 3 0 0 3 3 3 0 Nucleoplasmin Glyco_hydro_16 PF00722.16 EIW73038.1 - 2.8e-40 137.5 7.6 3.7e-40 137.1 5.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EIW73038.1 - 0.061 13.3 15.8 0.14 12.1 11.0 1.6 1 0 0 1 1 1 0 Chitin recognition protein YrhK PF14145.1 EIW73039.1 - 4.6e-05 23.0 16.7 0.054 13.1 1.4 4.6 4 1 0 4 4 4 4 YrhK-like protein RhoGEF PF00621.15 EIW73040.1 - 1e-25 90.6 0.0 1.8e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Collagen PF01391.13 EIW73040.1 - 0.51 9.9 8.7 0.12 11.9 3.2 2.0 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Carn_acyltransf PF00755.15 EIW73044.1 - 6.4e-152 506.6 0.0 7.5e-152 506.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Abhydro_lipase PF04083.11 EIW73046.1 - 6.3e-16 57.4 0.0 1.2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EIW73046.1 - 1.7e-06 28.0 0.1 1.7e-06 28.0 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW73046.1 - 0.0014 18.4 0.0 0.0022 17.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW73046.1 - 0.021 14.3 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF605 PF04652.11 EIW73047.1 - 7 5.9 10.3 10 5.3 7.1 1.1 1 0 0 1 1 1 0 Vta1 like Acetyltransf_3 PF13302.1 EIW73048.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW73049.1 - 3.3e-13 49.9 0.0 5.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW73049.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EIW73049.1 - 0.0019 18.1 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW73049.1 - 0.0022 17.6 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIW73049.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1749 PF08538.5 EIW73056.1 - 1.6e-77 260.4 0.0 2e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EIW73056.1 - 1.3e-10 41.5 0.2 1.9e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW73056.1 - 1.6e-07 31.2 0.0 1.2e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EIW73056.1 - 0.0036 16.6 0.0 0.005 16.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.16 EIW73056.1 - 0.1 11.8 0.0 7.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.13 EIW73056.1 - 0.1 11.8 0.0 0.38 9.9 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family BING4CT PF08149.6 EIW73056.1 - 0.14 11.6 0.1 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 BING4CT (NUC141) domain DUF1754 PF08555.5 EIW73057.1 - 1.3 9.6 13.5 0.045 14.3 3.8 2.2 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) NST1 PF13945.1 EIW73057.1 - 3.6 7.6 9.9 4.1 7.4 3.6 2.0 1 1 1 2 2 2 0 Salt tolerance down-regulator EF-hand_1 PF00036.27 EIW73059.1 - 5.7e-23 78.4 14.4 2e-08 32.9 1.7 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EIW73059.1 - 3.7e-21 75.0 8.5 9.1e-14 51.3 2.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIW73059.1 - 5.3e-21 72.5 12.2 1.5e-07 30.6 0.2 4.0 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EIW73059.1 - 2.9e-19 68.4 10.8 6.4e-14 51.3 1.1 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EIW73059.1 - 6.8e-14 50.4 11.0 4e-05 22.7 0.9 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EIW73059.1 - 1.8e-11 43.8 0.2 1.4e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EIW73059.1 - 1.6e-07 31.0 1.6 0.01 15.5 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF4373 PF14297.1 EIW73059.1 - 0.021 15.0 0.0 0.85 9.9 0.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4373) SPARC_Ca_bdg PF10591.4 EIW73059.1 - 0.029 14.4 0.4 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SSrecog PF03531.9 EIW73062.1 - 8.1e-68 228.0 0.0 1.9e-67 226.8 0.0 1.6 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EIW73062.1 - 2.4e-23 81.9 0.0 1.3e-20 73.1 0.0 2.5 2 0 0 2 2 2 2 Histone chaperone Rttp106-like Glyco_hydro_31 PF01055.21 EIW73063.1 - 1.9e-159 531.2 0.0 2.3e-159 530.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW73063.1 - 1.5e-09 37.5 0.7 3.6e-09 36.3 0.1 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like Chorismate_bind PF00425.13 EIW73064.1 - 2.8e-86 289.0 0.0 1.7e-85 286.4 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.23 EIW73064.1 - 8.9e-36 123.1 0.0 1.4e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIW73064.1 - 2.2e-09 37.0 0.0 4.4e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase C26 Anth_synt_I_N PF04715.8 EIW73064.1 - 0.00019 21.4 0.1 0.001 19.0 0.0 2.2 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Tet_JBP PF12851.2 EIW73065.1 - 7.1e-06 25.4 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Alpha_kinase PF02816.13 EIW73066.1 - 1.1e-13 51.2 0.0 3.2e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 Alpha-kinase family 5-FTHF_cyc-lig PF01812.15 EIW73068.1 - 9.7e-34 116.7 0.0 1.4e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Ricin_B_lectin PF00652.17 EIW73069.1 - 2.2e-10 40.6 2.6 0.00011 22.1 0.5 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIW73069.1 - 0.00086 19.6 1.7 0.16 12.3 0.1 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIW73070.1 - 4.8e-14 52.4 6.9 8.1e-14 51.7 4.8 1.4 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EIW73070.1 - 3e-06 27.5 0.9 0.00021 21.6 0.1 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like MA-Mit PF09245.5 EIW73070.1 - 0.092 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen Sugar_tr PF00083.19 EIW73071.1 - 7.3e-73 245.6 14.1 8.6e-73 245.4 9.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW73071.1 - 2.7e-19 69.0 8.5 2.7e-19 69.0 5.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW73071.1 - 0.00011 20.5 2.0 0.00011 20.5 1.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TauD PF02668.11 EIW73072.1 - 2.2e-26 93.0 0.0 2.7e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-Fe_Oxy_2 PF10014.4 EIW73072.1 - 0.33 10.3 1.2 1.9 7.7 0.0 2.5 2 1 1 3 3 3 0 2OG-Fe dioxygenase GFA PF04828.9 EIW73073.1 - 1.5e-16 60.0 1.3 2.1e-16 59.6 0.9 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2154 PF09922.4 EIW73073.1 - 0.11 12.1 0.1 1.8 8.2 0.0 2.1 1 1 1 2 2 2 0 Cell wall-active antibiotics response protein (DUF2154) MutS_V PF00488.16 EIW73074.1 - 2.2e-56 190.9 0.0 3.7e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIW73074.1 - 1.3e-21 77.3 0.1 3.1e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 MutS domain III AAA_29 PF13555.1 EIW73074.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MutS_IV PF05190.13 EIW73074.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 MutS family domain IV AAA_22 PF13401.1 EIW73074.1 - 0.11 12.6 0.0 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain PAP_central PF04928.12 EIW73075.1 - 2.6e-97 324.5 0.0 3.4e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EIW73075.1 - 5.3e-35 120.2 0.0 9.3e-35 119.4 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EIW73075.1 - 1.5e-06 28.4 0.0 2.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EIW73075.1 - 0.3 8.5 0.0 0.45 7.9 0.0 1.1 1 0 0 1 1 1 0 Nrap protein Lysis_col PF02402.11 EIW73076.1 - 5.8 6.5 5.5 26 4.4 0.0 2.7 3 0 0 3 3 3 0 Lysis protein Acetyltransf_1 PF00583.19 EIW73077.1 - 5.6e-10 39.1 0.0 8.1e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW73077.1 - 1.9e-08 34.3 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW73077.1 - 5.3e-08 32.9 0.0 7.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIW73077.1 - 6e-05 22.8 0.0 9.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EIW73077.1 - 0.00013 21.6 0.0 0.00029 20.5 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_5 PF13444.1 EIW73077.1 - 0.00088 19.8 0.0 0.046 14.2 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW73077.1 - 0.0045 16.8 0.0 0.009 15.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW73077.1 - 0.034 14.3 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TonB_C PF03544.9 EIW73077.1 - 0.075 13.2 0.0 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 Gram-negative bacterial TonB protein C-terminal CorA PF01544.13 EIW73078.1 - 1.5e-31 109.5 6.8 1.4e-19 70.2 0.1 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein RRM_1 PF00076.17 EIW73079.1 - 2.5e-11 43.0 0.0 2.1e-06 27.2 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW73079.1 - 5.2e-05 23.0 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW73079.1 - 0.005 16.8 0.0 0.31 11.0 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Aminotran_4 PF01063.14 EIW73080.1 - 9.2e-16 57.9 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV RRS1 PF04939.7 EIW73083.1 - 4.7e-56 188.7 1.2 7.3e-56 188.1 0.9 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) SUI1 PF01253.17 EIW73084.1 - 2.5e-21 75.2 0.5 8.4e-21 73.5 0.8 1.5 2 0 0 2 2 2 1 Translation initiation factor SUI1 NARP1 PF12569.3 EIW73084.1 - 0.13 10.9 6.1 0.17 10.6 4.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 UIM PF02809.15 EIW73085.1 - 0.00034 19.9 0.5 0.00034 19.9 0.3 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif DUF342 PF03961.8 EIW73085.1 - 0.24 9.7 4.3 0.38 9.1 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Matrilin_ccoil PF10393.4 EIW73085.1 - 0.63 9.4 5.1 5.8 6.3 0.3 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Syntaxin PF00804.20 EIW73085.1 - 2 8.6 8.4 2.4 8.3 3.7 2.3 2 0 0 2 2 2 0 Syntaxin Phosphodiest PF01663.17 EIW73088.1 - 1.5e-72 244.9 0.0 1.9e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIW73088.1 - 0.0055 15.9 0.0 0.037 13.2 0.0 2.1 2 0 0 2 2 2 1 Sulfatase Peptidase_C74 PF12387.3 EIW73089.1 - 0.2 10.8 0.4 0.81 8.8 0.2 1.9 2 0 0 2 2 2 0 Pestivirus NS2 peptidase zf-AN1 PF01428.11 EIW73089.1 - 0.23 11.3 4.0 0.46 10.4 2.8 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger zf-MYND PF01753.13 EIW73089.1 - 0.25 11.2 4.6 0.46 10.4 3.2 1.4 1 0 0 1 1 1 0 MYND finger HABP4_PAI-RBP1 PF04774.10 EIW73090.1 - 0.87 10.1 11.7 1.1 9.7 8.1 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Macoilin PF09726.4 EIW73091.1 - 0.17 10.1 17.5 0.25 9.6 12.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Chitin_synth_1 PF01644.12 EIW73092.1 - 1.4e-80 268.7 0.0 2.2e-80 268.1 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIW73092.1 - 4.4e-31 106.3 0.1 9.9e-31 105.2 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIW73092.1 - 3.6e-27 94.9 0.5 1.3e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EIW73092.1 - 9.1e-06 25.5 7.4 9.1e-06 25.5 5.1 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW73092.1 - 5e-05 23.2 0.0 0.00019 21.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Per1 PF04080.8 EIW73093.1 - 4.2e-83 278.8 1.4 5.3e-83 278.5 1.0 1.0 1 0 0 1 1 1 1 Per1-like ELO PF01151.13 EIW73094.1 - 1.5e-61 207.8 17.7 1.8e-61 207.6 12.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2714 PF10896.3 EIW73094.1 - 0.012 15.4 0.1 0.074 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2714) Enolase_C PF00113.17 EIW73095.1 - 2.4e-145 483.0 0.0 3.2e-145 482.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EIW73095.1 - 6.7e-54 181.3 0.0 1.1e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EIW73095.1 - 2.7e-05 24.1 0.0 6.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EIW73095.1 - 0.00087 18.2 0.1 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus CDC27 PF09507.5 EIW73096.1 - 9.2e-34 117.3 40.2 4.2e-29 102.0 27.8 2.1 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 SKI PF01202.17 EIW73098.1 - 2.5e-06 27.4 0.0 7.5e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EIW73098.1 - 0.00084 20.1 0.0 0.0019 19.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW73098.1 - 0.0044 16.9 0.0 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain CNF1 PF05785.7 EIW73098.1 - 0.063 12.1 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor Cytidylate_kin2 PF13189.1 EIW73098.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family CLTH PF10607.4 EIW73102.1 - 1.3e-39 135.1 0.0 2.1e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EIW73102.1 - 1.5e-10 40.4 0.3 7.4e-10 38.2 0.1 2.1 2 0 0 2 2 2 1 LisH DUF2342 PF10103.4 EIW73102.1 - 0.033 13.1 0.0 0.07 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2342) WD40 PF00400.27 EIW73103.1 - 2.2e-10 40.0 10.3 0.087 12.7 0.2 7.9 8 0 0 8 8 8 3 WD domain, G-beta repeat eIF2A PF08662.6 EIW73103.1 - 9.4e-07 28.7 0.0 0.0013 18.4 0.0 4.5 6 0 0 6 6 6 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW73103.1 - 0.00077 19.0 1.2 4.9 6.9 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EIW73103.1 - 0.0023 15.8 0.0 0.45 8.2 0.0 3.1 4 0 0 4 4 4 2 IKI3 family DPPIV_N PF00930.16 EIW73103.1 - 0.052 12.1 0.6 9 4.7 0.0 3.9 3 2 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Methyltransf_31 PF13847.1 EIW73104.1 - 4.2e-21 75.1 0.0 7.4e-21 74.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW73104.1 - 5.3e-19 68.4 0.0 1.1e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW73104.1 - 5.1e-17 62.4 0.0 8.2e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW73104.1 - 6e-17 61.9 0.0 9.8e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW73104.1 - 1.3e-13 50.9 0.0 1.8e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW73104.1 - 1e-12 47.6 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIW73104.1 - 4.9e-12 46.0 0.0 8.9e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW73104.1 - 2e-08 34.0 0.0 3.7e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EIW73104.1 - 2.1e-08 33.9 0.0 3.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW73104.1 - 1.2e-07 31.2 0.0 1.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIW73104.1 - 6.3e-07 29.4 0.0 1.5e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EIW73104.1 - 0.00029 19.9 0.0 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 EIW73104.1 - 0.00032 20.1 0.0 0.0005 19.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.14 EIW73104.1 - 0.00051 20.0 0.0 0.00074 19.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_5 PF01795.14 EIW73104.1 - 0.0011 18.2 0.0 0.0024 17.1 0.0 1.5 2 0 0 2 2 2 1 MraW methylase family CMAS PF02353.15 EIW73104.1 - 0.0026 16.9 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.8 EIW73104.1 - 0.0028 16.9 0.0 0.0057 15.9 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 DREV PF05219.7 EIW73104.1 - 0.0078 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.8 EIW73104.1 - 0.036 13.1 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Talin_middle PF09141.5 EIW73106.1 - 0.0021 17.7 2.4 0.0034 17.0 1.7 1.3 1 0 0 1 1 1 1 Talin, middle domain Antigen_Bd37 PF11641.3 EIW73106.1 - 0.015 14.5 0.2 0.021 14.1 0.1 1.1 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Pox_P4A PF03395.9 EIW73106.1 - 0.022 12.3 1.1 0.026 12.0 0.8 1.0 1 0 0 1 1 1 0 Poxvirus P4A protein DUF2877 PF11392.3 EIW73106.1 - 0.025 14.7 0.2 0.044 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) PP2C PF00481.16 EIW73107.1 - 3.1e-68 229.9 0.0 3.6e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIW73107.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Ribosomal_L23eN PF03939.8 EIW73108.1 - 4.5e-22 77.8 12.2 4.5e-22 77.8 8.4 2.5 2 2 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EIW73108.1 - 6.9e-19 67.5 1.2 6.9e-19 67.5 0.8 2.1 2 1 0 2 2 2 1 Ribosomal protein L23 ASL_C PF08328.6 EIW73108.1 - 0.08 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal NRDE PF05742.7 EIW73109.1 - 5.7e-50 170.1 0.0 1.4e-17 63.9 0.0 3.1 3 0 0 3 3 3 3 NRDE protein HIT PF01230.18 EIW73110.1 - 1e-23 83.6 0.0 1.3e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EIW73110.1 - 3.6e-14 52.9 0.0 4.7e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EIW73110.1 - 3.6e-07 29.8 0.0 5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.1 EIW73110.1 - 0.066 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 FH2 PF02181.18 EIW73111.1 - 2e-82 277.0 1.1 1.5e-81 274.1 0.0 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EIW73111.1 - 5.9e-15 55.1 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EIW73111.1 - 1.6e-06 27.6 0.1 3.5e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Diaphanous FH3 Domain FUSC PF04632.7 EIW73111.1 - 0.14 10.5 2.9 0.24 9.7 2.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF904 PF06005.7 EIW73111.1 - 1.5 9.1 11.8 55 4.1 0.1 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) TSC22 PF01166.13 EIW73111.1 - 6.3 6.8 6.8 29 4.7 0.2 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family 4HBT_2 PF13279.1 EIW73112.1 - 3e-13 50.2 0.1 1.3e-12 48.2 0.0 1.8 1 1 1 2 2 2 1 Thioesterase-like superfamily 4HBT PF03061.17 EIW73112.1 - 1.2e-07 31.6 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EIW73112.1 - 1.6e-07 30.5 0.0 4.8e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Acyl-ACP thioesterase Beta-lactamase PF00144.19 EIW73114.1 - 1.4e-41 142.5 0.0 3.3e-41 141.3 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase Choline_kin_N PF04428.9 EIW73115.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 Choline kinase N terminus zf-CCHC PF00098.18 EIW73116.1 - 0.00073 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW73116.1 - 0.34 11.1 7.3 0.091 12.9 2.9 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW73116.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Proteasome PF00227.21 EIW73118.1 - 1.5e-45 154.8 1.0 1.6e-45 154.7 0.0 1.5 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW73118.1 - 4.5e-13 48.2 0.1 7.1e-13 47.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TFIID-18kDa PF02269.11 EIW73119.1 - 3.7e-10 39.4 0.8 9.8e-10 38.1 0.6 1.8 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit zf-CCHC PF00098.18 EIW73120.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW73120.1 - 0.44 10.8 7.2 0.12 12.6 2.8 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Radial_spoke_3 PF06098.6 EIW73120.1 - 0.45 9.4 7.7 0.97 8.3 2.4 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 B56 PF01603.15 EIW73120.1 - 0.84 8.1 2.8 1.1 7.7 1.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) PRKCSH-like PF12999.2 EIW73121.1 - 3.3e-45 153.7 4.2 3.3e-45 153.7 2.9 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EIW73121.1 - 1.3e-29 102.6 0.2 3.9e-29 101.1 0.1 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EIW73121.1 - 1.7e-07 31.9 2.2 1.7e-07 31.9 1.5 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein HAUS-augmin3 PF14932.1 EIW73121.1 - 0.053 12.6 6.2 0.2 10.7 2.6 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1049 PF06305.6 EIW73121.1 - 2.4 7.6 9.0 0.064 12.7 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Cyt-b5 PF00173.23 EIW73122.1 - 2.6e-09 36.7 0.1 4.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ABC_tran PF00005.22 EIW73125.1 - 7e-22 78.2 0.0 9.3e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW73125.1 - 1.3e-09 38.5 0.0 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIW73125.1 - 1.8e-06 27.3 0.0 7.6e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EIW73125.1 - 0.00029 20.0 0.0 0.22 10.5 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain cobW PF02492.14 EIW73125.1 - 0.014 14.8 0.1 0.08 12.3 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.4 EIW73125.1 - 0.025 13.1 0.3 0.038 12.5 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class MobB PF03205.9 EIW73125.1 - 0.032 13.9 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EIW73125.1 - 0.04 13.0 0.1 0.072 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIW73125.1 - 0.05 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EIW73125.1 - 0.061 13.4 0.1 0.28 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIW73125.1 - 0.065 13.5 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EIW73125.1 - 0.12 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_17 PF13207.1 EIW73125.1 - 0.14 13.0 0.2 0.24 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EIW73126.1 - 1.9e-55 187.2 0.0 3e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIW73126.1 - 1.8e-34 117.8 0.0 5.5e-34 116.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 EIW73126.1 - 3.3e-29 100.5 0.1 1.4e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 EIW73126.1 - 2.2e-18 65.8 0.0 5.9e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIW73126.1 - 7.4e-14 51.6 0.1 5.4e-13 48.8 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Sdh5 PF03937.11 EIW73127.1 - 1.2e-18 66.6 0.4 1.6e-18 66.1 0.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Myb_DNA-binding PF00249.26 EIW73128.1 - 3.7e-12 46.1 1.0 7.6e-12 45.0 0.7 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW73128.1 - 2.7e-08 33.8 0.1 7.3e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.16 EIW73129.1 - 1.3e-07 31.0 0.0 2.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EIW73129.1 - 0.24 9.5 3.8 9.8 4.1 0.0 2.6 2 1 1 3 3 3 0 Beta-glucan synthesis-associated protein (SKN1) Pkinase PF00069.20 EIW73130.1 - 4.6e-46 157.0 0.0 6.2e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73130.1 - 4.6e-45 153.7 0.0 5.7e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW73130.1 - 1.2e-05 24.4 0.0 1.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW73130.1 - 0.00063 19.5 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW73130.1 - 0.0039 16.2 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Adaptin_N PF01602.15 EIW73131.1 - 7.6e-146 486.5 0.3 1.2e-145 485.8 0.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EIW73131.1 - 3.4e-19 69.3 1.9 1.1e-15 57.9 0.0 4.6 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EIW73131.1 - 4e-18 65.4 9.1 3e-05 24.2 0.1 6.3 2 1 3 7 7 7 5 HEAT repeats HEAT PF02985.17 EIW73131.1 - 3e-09 36.1 8.0 0.005 16.7 0.0 7.0 8 0 0 8 8 8 3 HEAT repeat Arm PF00514.18 EIW73131.1 - 5.6e-06 25.9 1.4 0.02 14.6 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EIW73131.1 - 4.6e-05 23.7 6.5 0.086 13.3 0.1 6.7 7 2 2 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 EIW73131.1 - 0.00046 19.6 0.2 0.36 10.1 0.0 4.0 4 1 1 5 5 5 1 CLASP N terminal Acyltransferase PF01553.16 EIW73132.1 - 1.3e-18 66.7 0.0 2.7e-18 65.6 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase Cofilin_ADF PF00241.15 EIW73133.1 - 2e-06 27.7 0.0 2.9e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Med14 PF08638.6 EIW73135.1 - 2e-21 76.1 0.4 3.9e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 Mediator complex subunit MED14 PAPS_reduct PF01507.14 EIW73136.1 - 7.9e-19 68.1 0.1 2e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.17 EIW73137.1 - 2.2e-17 62.4 0.0 3.8e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW73137.1 - 1e-13 51.0 0.0 1.7e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW73137.1 - 0.00015 21.5 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L2_C PF03947.13 EIW73139.1 - 2.4e-43 147.0 2.2 4.2e-43 146.2 1.5 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EIW73139.1 - 4.9e-15 55.2 0.4 9.8e-15 54.2 0.3 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF2340 PF10209.4 EIW73140.1 - 2.2e-42 144.0 0.2 2.9e-42 143.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Band_7 PF01145.20 EIW73141.1 - 4.6e-25 88.5 2.4 7.4e-25 87.8 1.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EIW73141.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DivIVA PF05103.8 EIW73141.1 - 0.22 11.5 2.7 0.38 10.8 1.9 1.3 1 0 0 1 1 1 0 DivIVA protein DUF3716 PF12511.3 EIW73143.1 - 0.17 11.5 5.5 0.31 10.6 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) GCR1_C PF12550.3 EIW73144.1 - 1.3e-16 60.2 1.5 1.6e-16 59.9 1.0 1.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Peptidase_C48 PF02902.14 EIW73147.1 - 8.4e-36 123.6 0.2 1e-35 123.3 0.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SMK-1 PF04802.10 EIW73149.1 - 1.3e-61 207.4 0.1 2.4e-61 206.6 0.1 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 GTSE1_N PF15259.1 EIW73149.1 - 0.064 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 14-3-3 PF00244.15 EIW73150.1 - 4.1e-115 382.8 5.8 4.6e-115 382.6 4.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF2408 PF10303.4 EIW73151.1 - 1.7e-52 177.1 0.3 5.3e-30 104.2 0.0 4.8 4 1 1 5 5 5 4 Protein of unknown function (DUF2408) DUF4446 PF14584.1 EIW73151.1 - 0.13 12.0 1.0 2.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Mod_r PF07200.8 EIW73151.1 - 1.7 8.5 9.2 0.64 9.9 1.5 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Prenyltrans PF00432.16 EIW73156.1 - 2.3e-26 91.0 15.4 3e-07 29.8 0.0 6.3 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIW73156.1 - 5.9e-19 68.5 0.0 5.7e-08 33.1 0.0 3.3 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIW73156.1 - 0.00013 21.9 0.0 0.6 10.1 0.0 3.2 2 1 1 3 3 3 3 Prenyltransferase-like NYAP_N PF15439.1 EIW73156.1 - 0.12 11.5 0.2 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter PBP1_TM PF14812.1 EIW73157.1 - 0.4 11.0 3.5 3 8.2 2.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF106 PF01956.11 EIW73157.1 - 0.8 9.2 3.6 0.9 9.0 0.2 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF106 Ribosomal_L7Ae PF01248.21 EIW73158.1 - 1.6e-26 91.6 2.2 2e-26 91.3 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_transf_22 PF03901.12 EIW73159.1 - 3.1e-57 194.4 18.5 1.8e-56 191.9 12.8 2.0 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family E_Pc_C PF06752.7 EIW73159.1 - 0.058 12.8 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus CAP_N PF01213.14 EIW73160.1 - 2.7e-74 250.2 2.6 2.7e-74 250.2 1.8 2.1 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EIW73160.1 - 7.8e-60 200.8 8.1 1.1e-59 200.2 5.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Myotub-related PF06602.9 EIW73161.1 - 6.5e-127 423.1 0.0 9.5e-127 422.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain APOC4 PF15119.1 EIW73161.1 - 0.00058 19.7 0.0 0.0067 16.3 0.0 2.6 2 0 0 2 2 2 1 Apolipoprotein C4 GRAM PF02893.15 EIW73161.1 - 0.0098 15.3 0.0 0.05 13.1 0.0 2.0 2 0 0 2 2 2 1 GRAM domain DSPc PF00782.15 EIW73161.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EIW73161.1 - 0.06 13.6 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family HTH_20 PF12840.2 EIW73161.1 - 0.099 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2413 PF10310.4 EIW73161.1 - 0.14 10.9 2.3 0.21 10.3 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) LSM PF01423.17 EIW73162.1 - 7.4e-18 63.8 0.1 8.5e-18 63.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Tim54 PF11711.3 EIW73165.1 - 3e-63 213.7 0.1 1.7e-62 211.2 0.1 2.0 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 GCV_T PF01571.16 EIW73166.1 - 1.4e-12 47.4 0.0 2.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EIW73166.1 - 0.14 12.1 0.0 0.6 10.1 0.0 1.9 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain WD40 PF00400.27 EIW73167.1 - 3.3e-15 55.2 0.6 0.01 15.6 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW73167.1 - 0.0084 15.5 0.0 0.021 14.3 0.0 1.6 2 0 0 2 2 2 1 PQQ-like domain Nop14 PF04147.7 EIW73167.1 - 0.53 8.1 30.2 0.7 7.7 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family RNase_H2-Ydr279 PF09468.5 EIW73167.1 - 0.94 8.6 6.8 1.4 8.0 4.7 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CDC45 PF02724.9 EIW73167.1 - 2.1 6.2 21.1 2.9 5.8 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EIW73167.1 - 2.6 7.2 26.6 3.8 6.6 18.4 1.2 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 EIW73167.1 - 2.7 7.2 26.5 4.2 6.6 18.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 EIW73167.1 - 3.8 7.3 13.2 5.8 6.7 9.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 EIW73167.1 - 5.3 6.7 6.1 8.7 6.0 4.3 1.3 1 0 0 1 1 1 0 DDHD domain Sas10_Utp3 PF04000.10 EIW73168.1 - 3.8e-12 46.2 0.9 7e-12 45.3 0.6 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Chromo PF00385.19 EIW73169.1 - 8.7e-05 22.1 0.5 0.00024 20.6 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ycf1 PF05758.7 EIW73169.1 - 0.002 15.9 0.8 0.0028 15.4 0.5 1.3 1 0 0 1 1 1 1 Ycf1 MDM1 PF15501.1 EIW73169.1 - 0.0031 16.5 11.3 0.0051 15.8 7.8 1.3 1 0 0 1 1 1 1 Nuclear protein MDM1 eIF_4EBP PF05456.6 EIW73169.1 - 0.015 14.9 3.0 4.3 7.0 0.0 3.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF788 PF05620.6 EIW73169.1 - 1.6 8.5 3.1 2.6 7.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Mito_carr PF00153.22 EIW73170.1 - 5.2e-06 26.0 0.0 0.0001 21.9 0.0 2.7 3 0 0 3 3 3 1 Mitochondrial carrier protein ATP_transf PF09830.4 EIW73171.1 - 1.2e-15 57.0 0.0 3.7e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 ATP adenylyltransferase G10 PF01125.12 EIW73173.1 - 2.2e-58 195.9 5.6 2.4e-58 195.7 3.9 1.0 1 0 0 1 1 1 1 G10 protein Terminase_GpA PF05876.7 EIW73173.1 - 2.8 6.1 8.4 4.1 5.6 5.8 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Mannosyl_trans2 PF04188.8 EIW73174.1 - 9.1e-58 196.2 26.1 1.4e-55 188.9 18.1 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) zf-C2H2 PF00096.21 EIW73175.1 - 2.5e-10 40.0 10.2 6.2e-05 23.0 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW73175.1 - 2.9e-09 36.7 10.1 1.1e-05 25.4 1.4 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW73175.1 - 1.3e-08 34.5 10.0 0.00021 21.4 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EIW73175.1 - 0.00047 20.2 4.1 0.12 12.5 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW73175.1 - 0.0079 16.3 2.2 0.24 11.6 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EIW73175.1 - 0.25 11.4 6.0 2.6 8.2 0.1 2.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EIW73175.1 - 3.4 7.7 10.6 12 5.9 4.6 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger DUF3414 PF11894.3 EIW73176.1 - 6.3e-247 822.3 0.0 7.8e-247 822.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Proteasom_PSMB PF10508.4 EIW73176.1 - 0.063 11.5 0.8 0.16 10.1 0.5 1.7 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Histone PF00125.19 EIW73177.1 - 6.6e-23 80.6 0.1 8.8e-23 80.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW73177.1 - 0.00027 20.9 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PfkB PF00294.19 EIW73178.1 - 1.9e-09 37.1 0.0 2.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Methyltransf_26 PF13659.1 EIW73179.1 - 8.5e-08 32.2 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW73179.1 - 3.1e-05 23.4 0.0 4.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Pkinase PF00069.20 EIW73180.1 - 2.9e-71 239.6 0.0 3.8e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73180.1 - 2.6e-36 125.0 0.0 3.4e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW73180.1 - 1.6e-16 60.1 1.2 2.2e-16 59.7 0.1 1.8 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EIW73180.1 - 9.5e-11 41.1 0.0 5.4e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIW73180.1 - 0.0016 17.5 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EIW73180.1 - 0.27 9.9 0.0 0.39 9.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BSD PF03909.12 EIW73181.1 - 8.6e-08 31.8 0.0 2.7e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 BSD domain DUF262 PF03235.9 EIW73182.1 - 1.7e-14 54.3 0.1 7.6e-14 52.2 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function DUF262 Coq4 PF05019.8 EIW73183.1 - 1.5e-86 288.9 0.0 1.7e-86 288.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TauD PF02668.11 EIW73184.1 - 2.9e-50 171.3 0.0 4.4e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EIW73184.1 - 0.0025 18.2 0.1 0.012 16.0 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF971) Tet_JBP PF12851.2 EIW73184.1 - 0.021 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily PIP5K PF01504.13 EIW73185.1 - 5.1e-87 291.1 0.1 7.1e-87 290.6 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Rubis-subs-bind PF09273.6 EIW73186.1 - 1.2e-08 34.9 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EIW73186.1 - 8.6e-07 29.3 0.0 7e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 SET domain TPK_catalytic PF04263.11 EIW73187.1 - 1.1e-21 76.6 0.0 1.6e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EIW73187.1 - 1e-12 47.5 0.0 1.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain HHH_2 PF12826.2 EIW73187.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif MULE PF10551.4 EIW73188.1 - 9.1e-14 51.4 1.3 9.4e-11 41.7 0.2 3.6 2 1 0 2 2 2 1 MULE transposase domain UCH PF00443.24 EIW73188.1 - 8.1e-10 38.2 0.0 2.2e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW73188.1 - 0.096 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase rve PF00665.21 EIW73188.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain UAF_Rrn10 PF05234.6 EIW73189.1 - 0.0046 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 UAF complex subunit Rrn10 DUF1510 PF07423.6 EIW73189.1 - 0.01 15.2 27.6 0.017 14.5 19.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 EIW73189.1 - 0.92 7.3 50.1 1.3 6.8 34.7 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 EIW73189.1 - 1.9 7.0 15.8 2.6 6.5 11.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.7 EIW73189.1 - 2.8 7.1 37.5 4.8 6.3 26.0 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EIW73189.1 - 4.4 5.6 45.1 7 4.9 31.3 1.2 1 0 0 1 1 1 0 Daxx Family SET PF00856.23 EIW73190.1 - 3.1e-11 43.8 0.0 3.4e-10 40.4 0.0 2.6 2 1 0 2 2 2 1 SET domain Zip PF02535.17 EIW73190.1 - 0.16 10.9 31.3 0.37 9.7 21.7 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Ank_2 PF12796.2 EIW73191.1 - 1.8e-16 60.2 0.0 3.8e-08 33.5 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIW73191.1 - 2.7e-08 34.0 0.1 7.9e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EIW73191.1 - 7.2e-08 31.8 0.1 5.2e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EIW73191.1 - 8e-07 29.1 0.8 0.0002 21.4 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW73191.1 - 2.8e-05 23.9 0.1 0.0085 16.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat MFS_1 PF07690.11 EIW73192.1 - 6.8e-26 90.8 57.2 1.7e-21 76.3 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM223 PF14640.1 EIW73192.1 - 0.017 15.0 1.5 0.017 15.0 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 223 Fumble PF03630.9 EIW73192.1 - 0.076 11.8 0.1 0.15 10.8 0.1 1.4 1 0 0 1 1 1 0 Fumble Tcp10_C PF07202.8 EIW73192.1 - 0.25 10.8 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 T-complex protein 10 C-terminus ABC1 PF03109.11 EIW73193.1 - 2.5e-22 79.0 0.0 2.7e-21 75.7 0.0 2.4 1 1 0 1 1 1 1 ABC1 family DUF1992 PF09350.5 EIW73193.1 - 1e-16 60.5 0.1 4.4e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) APH PF01636.18 EIW73193.1 - 0.004 16.9 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Bunya_RdRp PF04196.7 EIW73193.1 - 0.21 9.5 0.0 0.3 9.0 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase MRP-L20 PF12824.2 EIW73194.1 - 1.4e-06 28.3 0.0 1.5e-06 28.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EIW73194.1 - 2.4e-06 27.5 0.0 2.7e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 Neugrin HTH_36 PF13730.1 EIW73194.1 - 0.026 14.6 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF134 PF02001.11 EIW73194.1 - 0.036 13.9 0.0 0.038 13.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_Tnp_4 PF13613.1 EIW73194.1 - 0.063 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease ThiF PF00899.16 EIW73194.1 - 0.08 12.7 0.0 0.082 12.7 0.0 1.0 1 0 0 1 1 1 0 ThiF family Sigma70_r4 PF04545.11 EIW73194.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 Sigma-70, region 4 vATP-synt_AC39 PF01992.11 EIW73195.1 - 4.9e-103 344.7 0.0 5.5e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit zf-RING_2 PF13639.1 EIW73196.1 - 2.4e-12 46.4 7.0 3.5e-12 45.9 4.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW73196.1 - 3.4e-08 33.3 6.3 5e-08 32.8 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW73196.1 - 6.6e-08 32.1 4.9 9.7e-08 31.6 3.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIW73196.1 - 6.9e-08 32.4 5.2 1.7e-07 31.2 3.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EIW73196.1 - 1.1e-07 31.4 2.8 1.5e-07 30.9 1.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW73196.1 - 7.4e-07 28.9 1.0 1.4e-06 28.0 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EIW73196.1 - 9.5e-07 28.3 6.4 1.4e-06 27.8 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EIW73196.1 - 5.4e-05 23.1 4.3 8.6e-05 22.5 3.0 1.3 1 0 0 1 1 1 1 RING-variant domain PHD PF00628.24 EIW73196.1 - 0.00073 19.1 5.5 0.0011 18.5 3.8 1.3 1 0 0 1 1 1 1 PHD-finger Serglycin PF04360.7 EIW73196.1 - 0.051 13.2 0.1 0.073 12.8 0.1 1.3 1 0 0 1 1 1 0 Serglycin zf-RING_UBOX PF13445.1 EIW73196.1 - 0.076 12.7 2.0 0.18 11.5 1.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 EIW73196.1 - 0.081 12.9 4.8 0.15 12.0 3.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-PHD-like PF15446.1 EIW73196.1 - 0.16 11.2 1.6 0.3 10.3 1.1 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-Nse PF11789.3 EIW73196.1 - 0.23 10.9 2.3 0.56 9.7 1.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EIW73196.1 - 0.26 11.2 5.7 1.5 8.8 3.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EIW73196.1 - 0.35 10.6 7.2 0.2 11.4 2.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Kelch_4 PF13418.1 EIW73197.1 - 7.9e-35 118.3 29.6 5.8e-08 32.3 0.1 6.2 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EIW73197.1 - 1.6e-33 114.0 19.8 1e-08 35.0 0.1 6.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EIW73197.1 - 1.5e-32 111.0 15.3 2.9e-08 33.4 0.1 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EIW73197.1 - 1e-27 95.1 15.5 3.8e-05 23.6 0.0 6.2 3 2 3 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EIW73197.1 - 3.1e-26 90.6 10.6 1.6e-05 24.3 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EIW73197.1 - 6.3e-25 85.9 12.7 3.1e-05 23.5 0.1 6.3 6 0 0 6 6 6 6 Kelch motif LVIVD PF08309.6 EIW73197.1 - 0.038 12.9 0.0 6.9 5.7 0.0 2.5 2 0 0 2 2 2 0 LVIVD repeat PQQ_3 PF13570.1 EIW73197.1 - 0.56 10.5 16.8 7.2 7.0 0.1 5.7 6 1 0 6 6 6 0 PQQ-like domain DUF4477 PF14780.1 EIW73199.1 - 0.011 15.1 3.4 0.69 9.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) Pkinase PF00069.20 EIW73200.1 - 1.1e-26 93.5 0.0 3.7e-24 85.2 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73200.1 - 2.7e-17 62.7 0.0 2.6e-16 59.4 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase DUF3661 PF12400.3 EIW73201.1 - 3.7e-34 117.5 3.5 5.9e-34 116.9 2.4 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein AAA PF00004.24 EIW73202.1 - 8.8e-55 184.4 0.0 1.4e-40 138.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 EIW73202.1 - 9e-10 38.0 0.6 1.2e-07 31.2 0.0 2.8 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EIW73202.1 - 1.3e-09 38.2 0.4 0.0028 17.8 0.1 3.7 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.7 EIW73202.1 - 1.6e-07 30.6 0.1 0.017 14.1 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIW73202.1 - 1.9e-07 31.9 0.0 0.011 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EIW73202.1 - 2.1e-07 31.0 0.1 7e-06 26.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EIW73202.1 - 4.3e-07 28.9 0.0 0.011 14.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 EIW73202.1 - 4.7e-07 29.9 0.0 0.037 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 EIW73202.1 - 6.8e-07 28.9 1.0 0.032 13.9 0.0 2.8 3 0 0 3 3 2 2 Part of AAA domain AAA_33 PF13671.1 EIW73202.1 - 1.7e-06 28.0 0.0 0.04 13.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIW73202.1 - 1.7e-06 27.5 1.9 0.023 14.1 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 EIW73202.1 - 1.8e-06 27.7 0.0 0.0014 18.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EIW73202.1 - 5.9e-06 25.5 0.3 0.0045 16.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIW73202.1 - 6.4e-06 26.0 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIW73202.1 - 1.1e-05 24.9 3.3 0.5 9.7 0.1 4.1 2 2 2 4 4 4 2 AAA domain AAA_24 PF13479.1 EIW73202.1 - 1.8e-05 24.4 1.3 0.26 10.8 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EIW73202.1 - 2.3e-05 24.7 0.6 0.014 15.6 0.0 2.8 3 1 0 3 3 2 1 AAA domain ABC_tran PF00005.22 EIW73202.1 - 2.6e-05 24.5 0.1 0.065 13.5 0.1 2.5 2 0 0 2 2 2 2 ABC transporter RNA_helicase PF00910.17 EIW73202.1 - 2.8e-05 24.2 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 EIW73202.1 - 6.8e-05 22.0 0.1 0.24 10.4 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin KaiC PF06745.8 EIW73202.1 - 8.5e-05 21.7 0.6 0.012 14.7 0.1 2.8 3 0 0 3 3 3 1 KaiC AAA_11 PF13086.1 EIW73202.1 - 8.9e-05 22.1 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EIW73202.1 - 0.0001 21.9 0.2 0.17 11.5 0.0 3.2 2 1 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 EIW73202.1 - 0.00018 21.5 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EIW73202.1 - 0.00022 20.5 0.0 0.75 8.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.4 EIW73202.1 - 0.00037 19.5 0.2 0.48 9.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EIW73202.1 - 0.00048 19.7 0.0 0.31 10.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EIW73202.1 - 0.00055 19.5 0.0 0.48 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EIW73202.1 - 0.00068 19.1 0.0 0.81 9.1 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EIW73202.1 - 0.0017 18.1 0.5 8 6.0 0.2 3.4 2 1 1 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 EIW73202.1 - 0.0034 17.0 0.1 0.76 9.4 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 EIW73202.1 - 0.013 14.4 0.0 2.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 KTI12 PF08433.5 EIW73202.1 - 0.014 14.6 0.1 0.2 10.8 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NB-ARC PF00931.17 EIW73202.1 - 0.014 14.2 0.1 3.3 6.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 EIW73202.1 - 0.014 14.8 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain ResIII PF04851.10 EIW73202.1 - 0.029 14.2 0.1 11 5.7 0.1 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.20 EIW73202.1 - 0.033 13.7 0.0 4.2 6.8 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EIW73202.1 - 0.043 13.2 0.0 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IPT PF01745.11 EIW73202.1 - 0.083 12.0 0.1 2.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Viral_helicase1 PF01443.13 EIW73202.1 - 0.12 11.9 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FA_desaturase PF00487.19 EIW73203.1 - 1e-38 133.2 22.0 1.6e-38 132.6 15.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIW73203.1 - 4.6e-12 45.5 0.0 8.5e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Abi PF02517.11 EIW73203.1 - 0.11 12.5 2.8 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 CAAX protease self-immunity zf-CCHC PF00098.18 EIW73205.1 - 0.00023 20.9 1.3 0.00035 20.3 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EIW73205.1 - 0.057 13.0 0.5 0.2 11.3 0.4 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EIW73205.1 - 0.12 12.1 1.3 0.25 11.0 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 EIW73206.1 - 1.6e-12 47.2 0.0 2.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.7 EIW73207.1 - 4.2 5.1 5.7 5.7 4.7 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family zf-CCHC PF00098.18 EIW73208.1 - 0.019 14.8 4.3 0.041 13.8 3.0 1.6 1 0 0 1 1 1 0 Zinc knuckle Resolvase PF00239.16 EIW73208.1 - 0.021 14.6 1.6 0.044 13.6 1.1 1.5 1 0 0 1 1 1 0 Resolvase, N terminal domain zf-CCHC_2 PF13696.1 EIW73208.1 - 0.041 13.3 0.2 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4509 PF14970.1 EIW73211.1 - 0.068 12.8 0.3 0.15 11.6 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4509) Z1 PF10593.4 EIW73211.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Z1 domain FUSC PF04632.7 EIW73211.1 - 0.14 10.5 1.3 0.15 10.4 0.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Laminin_I PF06008.9 EIW73212.1 - 0.0042 16.4 0.1 0.011 15.0 0.1 1.6 1 1 0 1 1 1 1 Laminin Domain I Cyclin_N PF00134.18 EIW73215.1 - 4e-09 36.1 0.1 6.7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIW73215.1 - 9.1e-08 32.6 1.6 9.5e-08 32.5 0.3 1.8 2 1 0 2 2 2 1 Cyclin IMPDH PF00478.20 EIW73216.1 - 5.5e-137 456.3 1.3 6.9e-137 456.0 0.9 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EIW73216.1 - 2.4e-13 49.6 0.0 2.9e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EIW73216.1 - 1.9e-10 40.4 6.9 7.2e-08 31.9 3.0 2.4 3 0 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.13 EIW73216.1 - 2.5e-08 33.1 3.7 8.7e-08 31.3 2.6 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EIW73216.1 - 2.8e-08 33.3 0.2 7.3e-08 31.9 0.1 1.7 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EIW73216.1 - 0.0011 18.1 1.9 0.0024 16.9 1.3 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.9 EIW73216.1 - 0.0059 15.5 0.1 0.011 14.6 0.1 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 EIW73216.1 - 0.14 11.2 0.1 2 7.4 0.0 2.3 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase IBN_N PF03810.14 EIW73217.1 - 0.0019 18.0 0.1 0.0055 16.5 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EIW73217.1 - 0.0071 16.2 0.0 0.084 12.7 0.0 2.9 4 0 0 4 4 4 1 Exportin 1-like protein Cyclin_N PF00134.18 EIW73218.1 - 4.4e-12 45.6 0.1 9e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cpn60_TCP1 PF00118.19 EIW73219.1 - 3.6e-131 438.1 13.9 4.1e-131 437.9 9.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.20 EIW73220.1 - 6.6e-65 218.8 0.0 8.6e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73220.1 - 1.6e-39 135.5 0.0 2.3e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW73220.1 - 5.6e-05 22.9 0.0 0.28 10.8 0.0 2.9 1 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW73220.1 - 0.0027 16.7 0.0 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW73220.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dus PF01207.12 EIW73221.1 - 9.2e-67 225.0 0.0 1.9e-66 223.9 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 EIW73221.1 - 0.00012 21.2 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.12 EIW73221.1 - 0.0091 15.6 0.1 0.23 11.0 0.0 2.3 1 1 1 2 2 2 1 SOR/SNZ family His_biosynth PF00977.16 EIW73221.1 - 0.055 12.7 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF4376 PF14301.1 EIW73221.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) DHO_dh PF01180.16 EIW73221.1 - 0.15 10.9 0.0 0.41 9.5 0.0 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase ICE2 PF08426.5 EIW73222.1 - 8.7e-21 74.0 13.5 8.7e-21 74.0 9.4 2.1 1 1 1 2 2 2 1 ICE2 PP2C PF00481.16 EIW73223.1 - 1.4e-28 99.9 0.0 6.7e-27 94.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EIW73223.1 - 2.2e-06 27.2 0.0 9.6e-06 25.1 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C TPR_11 PF13414.1 EIW73224.1 - 5.4e-12 45.1 0.1 3.4e-10 39.4 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EIW73224.1 - 1.2e-05 24.6 0.3 0.0017 17.8 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat UBA PF00627.26 EIW73224.1 - 2.3e-05 24.0 0.0 5.9e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 EIW73224.1 - 0.00055 19.6 2.6 0.0088 15.8 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW73224.1 - 0.0027 17.5 0.0 0.0093 15.8 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat DnaJ PF00226.26 EIW73224.1 - 0.003 17.2 0.0 0.0088 15.7 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain S-AdoMet_synt_C PF02773.11 EIW73226.1 - 3.2e-76 253.6 0.1 5.6e-76 252.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EIW73226.1 - 7.7e-49 164.6 0.0 1.3e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EIW73226.1 - 5.4e-44 148.5 1.2 6.1e-44 148.3 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DDE_1 PF03184.14 EIW73228.1 - 1.9e-22 79.4 0.0 3e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW73228.1 - 1.1e-05 25.1 0.1 3.4e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW73228.1 - 0.0013 18.5 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EIW73228.1 - 0.0021 17.5 0.1 0.0048 16.4 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SR-25 PF10500.4 EIW73229.1 - 0.007 15.8 9.7 0.007 15.8 6.8 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.18 EIW73230.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW73230.1 - 0.27 11.5 9.2 0.069 13.3 4.2 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain B56 PF01603.15 EIW73230.1 - 0.64 8.5 2.3 0.85 8.1 1.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Mpp10 PF04006.7 EIW73234.1 - 0.056 11.8 25.2 0.07 11.4 17.4 1.0 1 0 0 1 1 1 0 Mpp10 protein CENP-T PF15511.1 EIW73234.1 - 0.36 10.0 15.7 0.44 9.7 10.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EIW73234.1 - 0.62 7.9 21.9 0.7 7.7 15.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EIW73234.1 - 0.76 7.7 14.5 0.92 7.4 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2146 PF10220.4 EIW73234.1 - 0.79 7.6 14.6 0.98 7.3 10.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) PLRV_ORF5 PF01690.12 EIW73234.1 - 0.85 8.7 10.2 0.95 8.5 7.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein GAGA_bind PF06217.7 EIW73234.1 - 1.1 9.2 4.3 1.1 9.1 3.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Plasmodium_Vir PF05795.6 EIW73234.1 - 1.1 8.4 6.2 1.3 8.1 4.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein BTV_NS2 PF04514.7 EIW73234.1 - 1.7 7.4 11.6 2 7.2 8.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RRN3 PF05327.6 EIW73234.1 - 2.9 5.8 8.7 3.9 5.4 6.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 OmpH PF03938.9 EIW73234.1 - 3.3 7.6 19.2 4.7 7.1 13.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spore_coat_CotO PF14153.1 EIW73234.1 - 3.4 7.0 21.1 5.1 6.4 14.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Hid1 PF12722.2 EIW73234.1 - 3.6 5.1 13.6 4 5.0 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 EIW73234.1 - 5.3 4.6 14.7 6.2 4.4 10.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF4175 PF13779.1 EIW73234.1 - 5.4 4.5 18.8 6.1 4.4 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RR_TM4-6 PF06459.7 EIW73234.1 - 6.7 6.5 21.4 8.8 6.1 14.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.5 EIW73234.1 - 8.9 4.5 7.2 9.3 4.5 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Daxx PF03344.10 EIW73234.1 - 9 4.6 21.2 9.4 4.5 14.7 1.0 1 0 0 1 1 1 0 Daxx Family zf-DNA_Pol PF08996.5 EIW73235.1 - 0.041 13.2 0.0 0.041 13.2 0.0 1.6 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DNA_pol_B_palm PF14792.1 EIW73236.1 - 8.1e-19 67.7 0.0 1.2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 EIW73236.1 - 3.7e-10 39.1 0.0 7.3e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 EIW73236.1 - 5.1e-05 23.5 0.0 9.9e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_thumb PF14791.1 EIW73236.1 - 0.0013 18.3 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb Rad9_Rad53_bind PF08605.5 EIW73236.1 - 0.052 13.3 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding DPM3 PF08285.6 EIW73237.1 - 1.4e-27 95.3 0.0 1.6e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Snf7 PF03357.16 EIW73238.1 - 1.4e-34 118.9 21.9 1.4e-34 118.9 15.2 1.6 1 1 1 2 2 2 1 Snf7 LUC7 PF03194.10 EIW73238.1 - 0.0086 15.6 3.3 0.0086 15.6 2.3 2.0 1 1 1 2 2 2 1 LUC7 N_terminus Lectin_N PF03954.9 EIW73238.1 - 0.01 15.2 2.3 0.014 14.8 0.0 2.1 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain PRA-PH PF01503.12 EIW73238.1 - 0.07 13.4 1.1 0.22 11.8 0.7 1.9 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4279 PF14106.1 EIW73238.1 - 0.09 12.6 0.2 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) Erp_C PF06780.6 EIW73238.1 - 0.3 10.9 8.0 0.4 10.5 0.9 2.2 2 0 0 2 2 2 0 Erp protein C-terminus DUF342 PF03961.8 EIW73238.1 - 0.96 7.7 10.1 0.91 7.8 4.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF342) VGLL4 PF15245.1 EIW73238.1 - 1.1 9.1 6.6 3.7 7.3 4.1 2.1 1 1 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 DUF826 PF05696.6 EIW73238.1 - 1.6 8.8 6.5 0.34 11.0 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF826) V_ATPase_I PF01496.14 EIW73238.1 - 2.3 5.9 9.8 2.4 5.8 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Soyouz_module PF14313.1 EIW73239.1 - 0.054 13.0 1.0 2.8 7.5 0.0 2.9 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) EF1G PF00647.14 EIW73240.1 - 1.6e-44 149.9 0.2 7e-44 147.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 EIW73240.1 - 3.8e-12 46.2 0.7 1e-11 44.8 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW73240.1 - 2.4e-09 37.0 0.5 5e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW73240.1 - 4.6e-07 29.9 0.0 1.4e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW73240.1 - 1e-06 28.6 0.0 1.5e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW73240.1 - 3.7e-06 27.3 0.1 1.6e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ribosomal_60s PF00428.14 EIW73240.1 - 0.0012 19.2 10.5 0.0033 17.7 7.3 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein GST_C_2 PF13410.1 EIW73240.1 - 0.0016 18.3 0.0 0.0057 16.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Sigma70_ner PF04546.8 EIW73240.1 - 0.018 14.6 1.4 0.035 13.7 1.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region YqzE PF14038.1 EIW73241.1 - 0.033 13.9 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 YqzE-like protein HLH PF00010.21 EIW73242.1 - 7.4e-15 54.3 0.6 7.4e-15 54.3 0.4 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FlgN PF05130.7 EIW73242.1 - 0.049 13.8 0.1 0.097 12.9 0.1 1.4 1 0 0 1 1 1 0 FlgN protein CPSF_A PF03178.10 EIW73243.1 - 6.6e-85 285.0 0.0 1.4e-84 283.9 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 EIW73243.1 - 1.9e-65 220.9 0.0 2.6e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PDEase_II PF02112.10 EIW73243.1 - 0.37 9.6 0.0 0.62 8.9 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II HIG_1_N PF04588.8 EIW73244.1 - 3.7e-06 26.5 1.0 7.2e-06 25.6 0.7 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region TctB PF07331.6 EIW73244.1 - 0.023 14.3 2.0 0.042 13.5 0.4 1.8 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family TrbI_Ftype PF09677.5 EIW73244.1 - 0.1 12.4 0.3 4.4 7.1 0.1 2.2 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) AAA_18 PF13238.1 EIW73245.1 - 1.3e-05 25.4 0.2 8.7e-05 22.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIW73245.1 - 0.00028 21.6 0.0 0.00063 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EIW73245.1 - 0.00044 19.5 0.3 0.0011 18.3 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EIW73245.1 - 0.00046 20.0 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EIW73245.1 - 0.0044 16.6 0.0 0.056 13.0 0.0 2.4 3 0 0 3 3 3 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.1 EIW73245.1 - 0.0098 15.8 0.0 0.037 14.0 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EIW73245.1 - 0.039 13.1 0.0 0.086 11.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 EIW73245.1 - 0.056 13.3 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EIW73245.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 EIW73245.1 - 0.11 11.5 0.1 0.22 10.5 0.0 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase APS_kinase PF01583.15 EIW73245.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase UCH PF00443.24 EIW73246.1 - 1.8e-48 165.0 0.0 2.8e-48 164.3 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW73246.1 - 1.3e-28 100.2 0.0 1.7e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EIW73246.1 - 0.0083 15.4 0.2 1.6 7.9 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase DZR PF12773.2 EIW73246.1 - 0.27 11.0 4.1 37 4.2 3.9 2.5 1 1 1 2 2 2 0 Double zinc ribbon Spc24 PF08286.6 EIW73247.1 - 2.5e-18 65.8 1.4 2.5e-18 65.8 0.9 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Enkurin PF13864.1 EIW73247.1 - 0.023 14.9 2.5 0.026 14.6 0.5 1.9 1 1 0 1 1 1 0 Calmodulin-binding DUF4407 PF14362.1 EIW73247.1 - 0.19 10.6 8.9 0.25 10.2 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.3 EIW73247.1 - 9.5 6.1 11.0 10 6.0 3.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MULE PF10551.4 EIW73248.1 - 1.1e-13 51.1 1.3 1e-10 41.5 0.2 3.6 2 1 0 2 2 2 1 MULE transposase domain UCH PF00443.24 EIW73248.1 - 1.9e-09 37.0 0.0 4.8e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW73248.1 - 0.034 13.5 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase rve PF00665.21 EIW73248.1 - 0.17 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Lum_binding PF00677.12 EIW73250.1 - 2.1e-40 136.4 0.2 1.3e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain Acyl-CoA_dh_1 PF00441.19 EIW73251.1 - 1.2e-42 145.5 0.3 2.3e-42 144.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIW73251.1 - 8.2e-36 123.0 0.1 1.5e-35 122.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EIW73251.1 - 3.4e-19 68.1 0.0 6.2e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIW73251.1 - 1.1e-14 54.7 0.2 2.2e-14 53.8 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain tRNA-synt_2c PF01411.14 EIW73252.1 - 0.0022 16.3 0.0 0.0031 15.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EIW73252.1 - 0.014 15.3 0.2 0.031 14.1 0.1 1.6 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain MmgE_PrpD PF03972.9 EIW73253.1 - 9.4e-45 152.5 0.0 3.3e-38 131.0 0.0 2.0 2 0 0 2 2 2 2 MmgE/PrpD family RabGAP-TBC PF00566.13 EIW73254.1 - 5.6e-34 117.4 0.0 9.9e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rav1p_C PF12234.3 EIW73255.1 - 8.7e-163 542.8 0.0 1.4e-162 542.1 0.0 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal MAPEG PF01124.13 EIW73256.1 - 1e-20 73.6 0.7 2e-20 72.7 0.2 1.6 1 1 1 2 2 2 1 MAPEG family DUF368 PF04018.8 EIW73256.1 - 0.22 10.6 4.4 1.9 7.5 2.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF368) MadM PF03818.8 EIW73256.1 - 0.39 10.3 4.3 0.6 9.7 0.4 2.7 3 0 0 3 3 3 0 Malonate/sodium symporter MadM subunit PAP_assoc PF03828.14 EIW73257.1 - 6e-23 80.5 0.2 1.1e-22 79.7 0.2 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EIW73257.1 - 7.1e-08 32.6 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 EIW73257.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm SOG2 PF10428.4 EIW73258.1 - 0.21 10.1 8.1 0.26 9.9 5.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_L3 PF00297.17 EIW73259.1 - 6.9e-112 373.1 4.8 8.5e-112 372.8 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 APH PF01636.18 EIW73260.1 - 7.7e-10 38.8 0.0 8e-05 22.4 0.0 2.5 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EIW73260.1 - 3.2e-09 36.1 0.0 2.7e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EIW73260.1 - 0.00016 20.9 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EIW73260.1 - 0.0012 18.2 0.0 0.47 9.7 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.20 EIW73260.1 - 0.0072 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF962 PF06127.6 EIW73261.1 - 1.1e-25 89.2 0.9 2.4e-25 88.2 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) BAG PF02179.11 EIW73262.1 - 0.00032 20.7 1.2 0.00032 20.7 0.8 2.8 2 0 0 2 2 2 1 BAG domain Voltage_CLC PF00654.15 EIW73263.1 - 7.7e-91 304.7 25.5 7.7e-91 304.7 17.7 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EIW73263.1 - 6.8e-10 38.5 0.4 4.9e-06 26.2 0.2 2.6 2 0 0 2 2 2 2 CBS domain Antimicrobial_2 PF08023.7 EIW73265.1 - 0.0073 16.5 1.7 0.12 12.7 0.1 2.5 2 0 0 2 2 2 1 Frog antimicrobial peptide DUF948 PF06103.6 EIW73265.1 - 0.09 12.6 0.2 2 8.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YtxH PF12732.2 EIW73265.1 - 0.14 12.4 0.2 0.14 12.4 0.1 2.5 2 0 0 2 2 2 0 YtxH-like protein Cpn60_TCP1 PF00118.19 EIW73266.1 - 1.5e-152 508.6 2.5 1.7e-152 508.4 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_S19 PF00203.16 EIW73267.1 - 4.1e-24 83.9 0.1 5.2e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Prenylcys_lyase PF07156.9 EIW73268.1 - 3e-29 102.0 0.0 4.3e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EIW73268.1 - 3.7e-11 42.8 0.1 9.2e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW73268.1 - 0.0012 18.8 0.0 0.047 13.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW73268.1 - 0.0032 16.4 0.0 0.22 10.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EIW73268.1 - 0.023 13.7 0.0 0.069 12.2 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EIW73268.1 - 0.15 11.1 0.3 0.23 10.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain SNF2_N PF00176.18 EIW73270.1 - 4.1e-83 278.6 0.7 9.2e-83 277.4 0.5 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EIW73270.1 - 1e-18 66.9 1.8 1e-18 66.9 1.3 2.0 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EIW73270.1 - 6.6e-17 61.1 0.0 9.6e-16 57.4 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EIW73270.1 - 4.2e-16 58.8 1.7 4.2e-16 58.8 1.2 3.2 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EIW73270.1 - 5.5e-15 54.9 4.5 5.5e-15 54.9 3.1 3.4 4 0 0 4 4 4 1 HSA QLQ PF08880.6 EIW73270.1 - 7.9e-08 31.5 4.6 1.9e-07 30.3 3.2 1.7 1 0 0 1 1 1 1 QLQ Aminotran_1_2 PF00155.16 EIW73272.1 - 1.3e-44 152.6 0.0 1.7e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW73272.1 - 0.15 11.2 0.0 0.45 9.6 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase NUDIX PF00293.23 EIW73273.1 - 1.7e-14 53.6 0.0 3.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SAM_PNT PF02198.11 EIW73275.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Fasciclin PF02469.17 EIW73276.1 - 8.9e-26 90.3 0.0 1e-13 51.4 0.0 3.2 2 1 0 2 2 2 2 Fasciclin domain KTI12 PF08433.5 EIW73277.1 - 2.8e-69 233.3 0.0 3.2e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EIW73277.1 - 1.9e-07 31.0 0.0 3.4e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW73277.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW73277.1 - 0.0022 18.8 0.0 0.0034 18.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EIW73277.1 - 0.036 14.0 0.0 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.15 EIW73277.1 - 0.14 11.8 0.2 0.98 9.0 0.2 2.0 1 1 0 1 1 1 0 Adenylylsulphate kinase WD40 PF00400.27 EIW73278.1 - 6.7e-49 162.1 3.1 8.9e-10 38.0 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIW73278.1 - 5.9e-06 24.6 0.1 0.0052 14.9 0.0 3.4 3 1 1 4 4 4 3 Nucleoporin Nup120/160 DUF2450 PF10475.4 EIW73278.1 - 0.16 10.8 0.8 0.26 10.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) zf-4CXXC_R1 PF10497.4 EIW73280.1 - 3.2e-08 33.6 14.1 6e-08 32.7 9.7 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-met PF12874.2 EIW73281.1 - 2e-07 30.9 18.7 0.2 11.8 0.1 6.8 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW73281.1 - 4e-07 29.9 24.0 0.04 14.0 1.2 6.7 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIW73281.1 - 3.2e-05 23.9 26.7 0.5 10.8 0.4 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW73281.1 - 5.4e-05 22.9 24.6 0.012 15.5 0.2 5.5 6 0 0 6 6 6 3 C2H2-type zinc finger Acetyltransf_3 PF13302.1 EIW73281.1 - 0.00058 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C2H2_2 PF12756.2 EIW73281.1 - 0.0016 18.4 18.9 0.16 12.1 2.6 4.9 3 2 1 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EIW73281.1 - 0.0035 16.9 0.3 0.0035 16.9 0.2 2.6 3 0 0 3 3 3 1 DBF zinc finger Acetyltransf_4 PF13420.1 EIW73281.1 - 0.037 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C2H2 PF00096.21 EIW73281.1 - 0.075 13.4 37.8 0.093 13.1 1.0 6.7 7 0 0 7 7 6 0 Zinc finger, C2H2 type OSTMP1 PF09777.4 EIW73281.1 - 0.11 11.6 2.1 3.2 6.8 0.1 3.0 3 0 0 3 3 3 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-AD PF07776.10 EIW73281.1 - 0.11 12.5 5.4 4.7 7.2 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) zf-H2C2_2 PF13465.1 EIW73281.1 - 0.79 10.1 15.3 1.1 9.7 0.1 5.4 5 0 0 5 5 5 0 Zinc-finger double domain DUF629 PF04780.7 EIW73281.1 - 4.2 5.7 15.2 1 7.7 0.1 4.6 3 2 2 5 5 5 0 Protein of unknown function (DUF629) Ank PF00023.25 EIW73282.1 - 4e-19 67.3 0.6 9.5e-07 28.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EIW73282.1 - 5.4e-18 65.1 0.1 5.5e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIW73282.1 - 2.1e-15 56.3 0.2 2.6e-06 27.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW73282.1 - 9.8e-15 53.2 0.2 5.3e-05 23.0 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EIW73282.1 - 1.3e-14 54.2 0.2 2.8e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Epimerase PF01370.16 EIW73283.1 - 1.3e-08 34.5 0.0 0.00016 21.1 0.0 2.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIW73283.1 - 0.00013 20.9 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EIW73283.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIW73283.1 - 0.0052 16.0 0.0 0.0097 15.1 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EIW73283.1 - 0.0096 16.2 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EIW73283.1 - 0.041 12.5 0.0 0.15 10.6 0.0 1.8 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIW73283.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EIW73284.1 - 1.7e-23 83.3 0.0 1.3e-22 80.4 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW73284.1 - 8.1e-11 41.1 0.0 1.1e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW73284.1 - 6.5e-09 36.0 0.0 2.4e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EIW73284.1 - 8.2e-08 32.3 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIW73284.1 - 0.00053 18.9 0.0 0.00085 18.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EIW73284.1 - 0.0043 16.0 0.1 0.35 9.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EIW73284.1 - 0.0055 15.6 0.0 0.012 14.5 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EIW73284.1 - 0.013 15.1 0.0 0.034 13.8 0.0 1.7 1 1 0 1 1 1 0 KR domain NmrA PF05368.8 EIW73284.1 - 0.05 12.8 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Ribonuclease_3 PF00636.21 EIW73285.1 - 1.1e-12 48.3 0.1 3.8e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIW73285.1 - 4.8e-11 42.7 0.0 7.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EIW73285.1 - 0.012 16.2 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif PX PF00787.19 EIW73286.1 - 9.8e-17 60.7 0.1 1.7e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EIW73286.1 - 3.2e-10 39.5 8.3 6.8e-10 38.4 5.8 1.6 1 0 0 1 1 1 1 SNARE domain FlaC_arch PF05377.6 EIW73286.1 - 1.3 8.9 4.2 2.5 8.0 0.8 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) zf-CCCH PF00642.19 EIW73287.1 - 3.4 7.4 13.6 0.13 12.0 2.8 3.0 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TBPIP PF07106.8 EIW73288.1 - 1.9e-34 118.6 6.8 3.5e-34 117.8 4.7 1.4 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Macoilin PF09726.4 EIW73288.1 - 0.0026 16.1 2.9 0.0039 15.5 2.0 1.2 1 0 0 1 1 1 1 Transmembrane protein Pox_A_type_inc PF04508.7 EIW73288.1 - 0.045 13.5 1.4 0.15 11.9 1.0 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF848 PF05852.6 EIW73288.1 - 0.072 12.9 1.2 0.15 11.8 0.8 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Img2 PF05046.9 EIW73288.1 - 0.076 13.2 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Nitroreductase PF00881.19 EIW73289.1 - 3.8e-12 46.3 0.0 5.2e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family DUF1673 PF07895.6 EIW73290.1 - 0.032 13.7 0.8 0.032 13.7 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) DUF2910 PF11139.3 EIW73290.1 - 0.12 11.4 0.2 0.12 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) DUF2976 PF11190.3 EIW73290.1 - 1.1 8.8 0.0 1.1 8.8 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) Ctr PF04145.10 EIW73291.1 - 4.1e-32 111.2 6.0 5.1e-32 110.8 4.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF962 PF06127.6 EIW73291.1 - 0.025 14.4 0.9 0.085 12.7 0.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Multi_Drug_Res PF00893.14 EIW73291.1 - 0.19 12.2 0.1 0.19 12.2 0.1 2.4 2 1 0 2 2 2 0 Small Multidrug Resistance protein DUF4534 PF15049.1 EIW73291.1 - 1.2 8.7 6.4 0.26 10.8 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) DUF2648 PF10855.3 EIW73291.1 - 3.9 6.9 5.1 4.2 6.8 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2648) WD40 PF00400.27 EIW73292.1 - 1.4e-12 46.9 0.3 2.6e-06 27.0 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat MULE PF10551.4 EIW73293.1 - 1.2e-11 44.5 0.4 3.2e-09 36.8 0.2 2.9 1 1 0 1 1 1 1 MULE transposase domain UCH PF00443.24 EIW73293.1 - 9.9e-10 37.9 0.0 1.8e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW73293.1 - 0.054 12.9 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase ETF PF01012.16 EIW73294.1 - 4.9e-35 120.6 0.0 6.2e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain EFG_C PF00679.19 EIW73294.1 - 0.074 12.9 0.0 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor G C-terminus ORC3_N PF07034.6 EIW73295.1 - 0.099 11.5 0.4 0.18 10.7 0.3 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Actin PF00022.14 EIW73296.1 - 4.6e-32 110.8 0.0 7.5e-30 103.6 0.0 2.3 1 1 0 1 1 1 1 Actin DUF3040 PF11239.3 EIW73296.1 - 0.092 12.8 0.1 0.29 11.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MutS_V PF00488.16 EIW73297.1 - 4e-80 268.5 0.0 6.3e-80 267.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIW73297.1 - 3.7e-31 108.4 1.5 6.5e-31 107.7 1.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EIW73297.1 - 1.5e-15 57.2 0.0 2.7e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EIW73297.1 - 7.1e-07 29.3 0.0 1.9e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.1 EIW73297.1 - 0.0075 16.1 0.1 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW73297.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EIW73297.1 - 0.38 11.0 0.1 0.38 11.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain His_Phos_2 PF00328.17 EIW73298.1 - 1.5e-32 113.3 0.0 1.8e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) LSM PF01423.17 EIW73299.1 - 6.9e-09 35.1 0.0 1.1e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.1 EIW73299.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain CAP_N PF01213.14 EIW73300.1 - 0.43 9.8 17.4 0.12 11.6 1.7 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal OGFr_N PF04664.8 EIW73301.1 - 1.7e-58 197.4 0.0 2e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region NMD3 PF04981.8 EIW73303.1 - 6.7e-73 244.6 0.3 9.5e-73 244.1 0.2 1.2 1 0 0 1 1 1 1 NMD3 family DUF1289 PF06945.8 EIW73303.1 - 0.0029 17.0 1.4 0.48 9.9 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1289) zf-dskA_traR PF01258.12 EIW73303.1 - 0.025 14.2 0.1 0.025 14.2 0.1 2.0 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.2 EIW73303.1 - 0.067 13.0 4.1 1.2 9.0 1.8 2.8 2 1 1 3 3 3 0 Double zinc ribbon Cys_Met_Meta_PP PF01053.15 EIW73304.1 - 7.4e-121 403.0 0.0 1e-120 402.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 EIW73304.1 - 6.2e-18 64.6 0.2 4.7e-17 61.8 0.2 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain Aminotran_1_2 PF00155.16 EIW73304.1 - 0.00011 21.2 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GHMP_kinases_C PF08544.8 EIW73304.1 - 0.00097 19.2 0.0 0.0031 17.6 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Met_gamma_lyase PF06838.6 EIW73304.1 - 0.0049 15.2 0.0 0.0075 14.6 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GalKase_gal_bdg PF10509.4 EIW73304.1 - 0.01 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Methyltransf_29 PF03141.11 EIW73304.1 - 0.43 8.8 0.0 0.66 8.2 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ecl1 PF12855.2 EIW73306.1 - 0.00011 21.4 2.1 0.00011 21.4 1.4 1.6 2 0 0 2 2 2 1 Life-span regulatory factor Fis1_TPR_N PF14852.1 EIW73306.1 - 0.077 12.3 0.1 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat YpzI PF14140.1 EIW73310.1 - 0.077 12.5 0.2 0.17 11.4 0.2 1.5 1 0 0 1 1 1 0 YpzI-like protein Autophagy_N PF03986.8 EIW73313.1 - 5.2e-47 159.2 2.1 5.3e-47 159.2 0.2 2.0 2 1 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EIW73313.1 - 4.8e-24 84.3 0.2 1e-23 83.2 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EIW73313.1 - 1.5e-12 46.4 3.6 2.7e-12 45.5 2.5 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal AhpC-TSA PF00578.16 EIW73318.1 - 3.4e-32 110.7 0.0 4.7e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW73318.1 - 1.8e-11 43.7 0.0 2.2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EIW73318.1 - 1.7e-05 24.3 0.0 3.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin RDD PF06271.7 EIW73319.1 - 9.1 6.1 13.4 1.4e+02 2.3 9.3 2.3 1 1 0 1 1 1 0 RDD family Fibrillarin PF01269.12 EIW73320.1 - 2.1e-111 370.3 0.1 2.4e-111 370.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EIW73320.1 - 1.8e-06 27.6 0.0 2.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EIW73320.1 - 0.0058 16.2 0.0 0.008 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW73320.1 - 0.0093 15.5 0.2 0.016 14.7 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EIW73320.1 - 0.049 13.6 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase UCH PF00443.24 EIW73321.1 - 3.5e-47 160.7 0.0 4.5e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW73321.1 - 1.4e-14 54.2 0.0 2.5e-10 40.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Methyltransf_31 PF13847.1 EIW73322.1 - 2.1e-10 40.4 0.0 4.3e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW73322.1 - 5.1e-10 39.9 0.0 8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW73322.1 - 4.7e-06 26.6 0.0 8.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW73322.1 - 7.1e-05 23.2 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW73322.1 - 0.00052 19.7 0.0 0.0016 18.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW73322.1 - 0.0057 17.1 0.0 0.022 15.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW73322.1 - 0.036 14.4 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Anillin PF08174.6 EIW73323.1 - 1.4e-08 34.9 0.6 5.7e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 EIW73323.1 - 2.2e-05 24.5 0.0 8.9e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 PH domain Galactosyl_T PF01762.16 EIW73324.1 - 0.032 13.8 0.0 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 Galactosyltransferase Tubulin PF00091.20 EIW73325.1 - 1.4e-61 208.0 0.0 2.6e-61 207.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIW73325.1 - 2.5e-40 137.4 0.5 4.6e-40 136.5 0.4 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EIW73325.1 - 0.0022 17.4 0.0 0.0066 15.9 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain SOR_SNZ PF01680.12 EIW73326.1 - 1.1e-110 368.2 6.1 1.6e-110 367.5 4.3 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EIW73326.1 - 1.8e-09 37.0 6.5 6.3e-07 28.7 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EIW73326.1 - 9.5e-05 21.3 0.9 0.079 11.7 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EIW73326.1 - 0.0016 17.4 0.3 0.16 10.9 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 EIW73326.1 - 0.005 15.7 0.1 0.055 12.3 0.0 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IGPS PF00218.16 EIW73326.1 - 0.0062 15.6 0.0 0.075 12.0 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 EIW73326.1 - 0.0087 15.2 5.7 0.01 14.9 0.1 2.5 2 1 0 2 2 2 1 Nitronate monooxygenase PEP_mutase PF13714.1 EIW73326.1 - 0.016 14.4 0.8 0.065 12.4 0.1 2.2 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase His_biosynth PF00977.16 EIW73326.1 - 0.033 13.4 1.4 0.58 9.3 0.0 2.6 2 1 0 2 2 2 0 Histidine biosynthesis protein BSP_II PF05432.6 EIW73327.1 - 0.003 16.8 7.6 0.015 14.5 5.8 1.7 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 EIW73327.1 - 0.13 11.7 7.7 0.2 11.1 5.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin Dicty_REP PF05086.7 EIW73327.1 - 1.4 6.5 5.0 1.9 6.1 3.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NOA36 PF06524.7 EIW73327.1 - 2.4 7.3 4.8 3.5 6.8 3.4 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 EIW73327.1 - 4.3 7.6 11.4 7.8 6.7 7.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Prp19_bind PF06991.6 EIW73327.1 - 6.1 6.0 9.8 9.3 5.4 6.8 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain RabGAP-TBC PF00566.13 EIW73335.1 - 6.6e-52 176.0 0.3 9.5e-52 175.5 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_6 PF14259.1 EIW73336.1 - 7.3e-07 29.0 0.0 3.2e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW73336.1 - 7.4e-07 28.9 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EIW73336.1 - 2.7e-06 27.4 0.2 2.7e-06 27.4 0.1 1.8 2 0 0 2 2 2 1 PWI domain Nup35_RRM_2 PF14605.1 EIW73336.1 - 9.7e-06 25.2 0.0 0.00015 21.4 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 EIW73336.1 - 0.00072 19.1 0.0 0.11 12.1 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIW73336.1 - 0.00074 19.2 0.0 0.056 13.1 0.0 2.5 2 0 0 2 2 2 1 Limkain b1 zf-CCCH PF00642.19 EIW73336.1 - 0.003 17.1 2.6 0.0052 16.4 1.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EIW73336.1 - 0.009 15.8 1.4 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif DUF45 PF01863.12 EIW73336.1 - 0.45 10.2 3.0 1.7 8.3 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF45 DUF3584 PF12128.3 EIW73336.1 - 1.1 6.4 12.1 1.6 5.9 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 EIW73336.1 - 2 7.4 11.7 3.2 6.7 8.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA PF00004.24 EIW73338.1 - 1.1e-29 103.2 0.0 2.1e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW73338.1 - 1.7e-08 34.7 0.0 3.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW73338.1 - 6.7e-07 29.4 1.7 6.1e-06 26.3 0.3 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EIW73338.1 - 1.9e-06 28.7 0.0 4.7e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIW73338.1 - 2.7e-06 26.9 0.1 0.011 15.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.1 EIW73338.1 - 5.5e-06 26.7 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW73338.1 - 1.2e-05 25.2 0.0 3.3e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW73338.1 - 2.1e-05 24.3 0.3 0.026 14.1 0.1 2.3 1 1 1 2 2 2 2 Archaeal ATPase AAA_2 PF07724.9 EIW73338.1 - 9e-05 22.4 0.0 0.00027 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EIW73338.1 - 0.0001 21.9 0.2 0.00032 20.3 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_14 PF13173.1 EIW73338.1 - 0.00056 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EIW73338.1 - 0.00075 19.1 0.0 0.002 17.7 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EIW73338.1 - 0.00076 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EIW73338.1 - 0.001 18.3 0.0 0.0024 17.1 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 RuvB_N PF05496.7 EIW73338.1 - 0.0016 17.5 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad51 PF08423.6 EIW73338.1 - 0.0019 17.1 0.1 0.074 11.9 0.1 2.1 1 1 1 2 2 2 1 Rad51 NACHT PF05729.7 EIW73338.1 - 0.0021 17.7 0.2 0.0076 15.9 0.1 2.0 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EIW73338.1 - 0.0024 18.0 0.0 0.0059 16.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 EIW73338.1 - 0.0027 17.3 0.0 0.0058 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW73338.1 - 0.0027 17.9 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.9 EIW73338.1 - 0.0031 17.2 0.1 0.0082 15.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EIW73338.1 - 0.0037 17.2 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIW73338.1 - 0.0041 16.6 0.0 0.0095 15.4 0.0 1.6 2 0 0 2 2 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EIW73338.1 - 0.0042 16.0 0.2 0.023 13.5 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 EIW73338.1 - 0.0049 15.6 0.0 0.0079 14.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EIW73338.1 - 0.0096 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIW73338.1 - 0.012 14.6 0.0 0.031 13.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EIW73338.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EIW73338.1 - 0.035 13.6 0.0 0.087 12.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain SKI PF01202.17 EIW73338.1 - 0.045 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase Mg_chelatase PF01078.16 EIW73338.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 EIW73338.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EIW73338.1 - 0.089 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.7 EIW73338.1 - 0.093 12.3 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.4 EIW73338.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 EIW73338.1 - 0.12 10.8 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EIW73338.1 - 0.15 11.2 0.0 0.36 10.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein VMA21 PF09446.5 EIW73340.1 - 5.6e-13 48.6 8.0 8e-13 48.1 5.6 1.3 1 0 0 1 1 1 1 VMA21-like domain zf-CCHC PF00098.18 EIW73341.1 - 0.0055 16.5 1.9 0.0094 15.8 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle FANCI_HD2 PF14680.1 EIW73341.1 - 0.087 11.9 1.7 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 FANCI helical domain 2 CENP-F_leu_zip PF10473.4 EIW73341.1 - 1.5 8.7 12.8 0.074 12.9 1.8 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 EIW73341.1 - 2.6 8.4 6.8 24 5.3 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EIW73341.1 - 3.6 7.1 11.8 2.4 7.7 1.6 2.2 2 0 0 2 2 2 0 IncA protein rve PF00665.21 EIW73342.1 - 9.8e-19 67.6 0.0 1.8e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIW73342.1 - 2.3e-08 33.5 0.8 5.2e-08 32.4 0.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Transposase_21 PF02992.9 EIW73345.1 - 4.3e-09 35.8 0.0 8.6e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 ArabFuran-catal PF09206.6 EIW73345.1 - 0.21 10.4 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B, catalytic DUF4218 PF13960.1 EIW73345.1 - 0.22 10.9 0.0 0.62 9.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) FtsJ PF01728.14 EIW73346.1 - 4.9e-58 196.1 0.0 7.5e-58 195.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.20 EIW73346.1 - 2.2e-54 184.3 0.0 3.1e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73346.1 - 1.8e-30 105.8 0.0 2.6e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CbiA PF01656.18 EIW73346.1 - 0.23 10.8 0.1 0.64 9.3 0.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Kinase-like PF14531.1 EIW73346.1 - 0.42 9.5 0.0 0.9 8.4 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Daxx PF03344.10 EIW73354.1 - 0.00065 18.3 11.0 0.00071 18.2 7.6 1.0 1 0 0 1 1 1 1 Daxx Family Paf1 PF03985.8 EIW73354.1 - 0.56 8.8 6.2 0.64 8.7 4.3 1.0 1 0 0 1 1 1 0 Paf1 DUF2722 PF10846.3 EIW73354.1 - 1.5 7.7 5.5 1.7 7.5 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF1501 PF07394.7 EIW73355.1 - 0.052 12.3 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) UPF0020 PF01170.13 EIW73356.1 - 5.9e-13 48.7 0.0 9.4e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EIW73356.1 - 8.8e-12 45.0 0.0 3e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EIW73356.1 - 0.06 12.8 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 DNA methylase PTPA PF03095.10 EIW73357.1 - 1.7e-75 254.0 0.0 2e-75 253.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TFCD_C PF12612.3 EIW73358.1 - 4.8e-18 65.2 0.5 1e-15 57.6 0.0 3.6 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 EIW73358.1 - 4.6e-06 26.8 3.7 0.039 14.2 0.0 4.9 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EIW73358.1 - 8.7e-05 22.8 14.2 0.003 18.0 0.0 6.6 7 1 0 7 7 7 2 HEAT-like repeat HEAT PF02985.17 EIW73358.1 - 0.0026 17.6 9.7 0.07 13.2 0.0 7.1 8 0 0 8 8 8 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EIW73358.1 - 0.0044 17.3 0.1 3.9 7.9 0.0 3.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region FliD_C PF07195.7 EIW73358.1 - 0.017 14.4 0.0 0.042 13.1 0.0 1.7 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Ras PF00071.17 EIW73359.1 - 1.9e-56 189.9 0.1 2.2e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW73359.1 - 2.5e-18 66.6 0.0 4.6e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW73359.1 - 1.5e-13 50.4 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW73359.1 - 2.1e-07 30.3 0.0 2.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW73359.1 - 3.7e-07 29.7 0.0 6.2e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW73359.1 - 7.5e-07 29.1 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIW73359.1 - 0.00039 20.5 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EIW73359.1 - 0.00081 18.9 0.2 0.056 12.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EIW73359.1 - 0.0011 18.5 0.1 0.1 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EIW73359.1 - 0.0013 17.9 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIW73359.1 - 0.0037 17.2 0.0 0.0094 15.9 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 EIW73359.1 - 0.0047 16.5 0.2 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain Septin PF00735.13 EIW73359.1 - 0.0053 15.8 0.1 0.043 12.8 0.0 2.2 2 1 0 2 2 2 1 Septin Arch_ATPase PF01637.13 EIW73359.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 EIW73359.1 - 0.0088 15.5 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_5 PF07728.9 EIW73359.1 - 0.011 15.4 0.0 0.065 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRPRB PF09439.5 EIW73359.1 - 0.012 14.8 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MobB PF03205.9 EIW73359.1 - 0.017 14.7 0.1 0.049 13.3 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EIW73359.1 - 0.018 14.4 0.0 0.062 12.7 0.0 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EIW73359.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 EIW73359.1 - 0.12 11.6 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B ATG16 PF08614.6 EIW73360.1 - 7.8e-29 100.8 16.6 9.5e-29 100.6 11.5 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC155 PF14662.1 EIW73360.1 - 0.004 16.7 10.1 0.0053 16.3 7.0 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 PH_7 PF15408.1 EIW73360.1 - 0.007 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Cytochrom_B562 PF07361.6 EIW73360.1 - 0.074 13.4 7.2 0.068 13.5 1.2 2.7 2 2 0 2 2 2 0 Cytochrome b562 TMF_TATA_bd PF12325.3 EIW73360.1 - 0.092 12.4 10.7 0.25 11.0 2.2 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 EIW73360.1 - 0.098 13.0 8.9 0.61 10.4 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4546 PF15079.1 EIW73360.1 - 0.14 11.3 2.2 0.17 11.0 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) RsbRD_N PF14361.1 EIW73360.1 - 0.17 12.3 3.6 0.29 11.5 0.1 2.3 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Lebercilin PF15619.1 EIW73360.1 - 0.17 11.2 10.7 0.74 9.1 7.4 2.2 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.3 EIW73360.1 - 0.23 11.3 11.7 1.7 8.5 3.2 2.1 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding HAUS-augmin3 PF14932.1 EIW73360.1 - 0.25 10.5 8.2 0.35 10.0 5.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.3 EIW73360.1 - 0.28 10.4 9.8 0.034 13.4 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Toxin_39 PF15500.1 EIW73360.1 - 0.58 10.3 3.3 10 6.3 0.7 2.4 1 1 0 2 2 2 0 Putative RNase-like toxin TMF_DNA_bd PF12329.3 EIW73360.1 - 0.6 9.9 9.9 0.067 13.0 2.1 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Tup_N PF08581.5 EIW73360.1 - 0.69 10.1 6.0 2.2 8.5 1.5 2.5 1 1 2 3 3 3 0 Tup N-terminal TBPIP PF07106.8 EIW73360.1 - 0.73 9.3 7.9 0.43 10.1 1.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FUSC PF04632.7 EIW73360.1 - 3.2 6.0 8.3 2.5 6.4 0.0 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF1470 PF07336.6 EIW73360.1 - 3.5 7.9 9.3 2.9 8.2 4.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1470) IncA PF04156.9 EIW73360.1 - 5.9 6.4 13.8 7.9 6.0 7.6 2.2 1 1 1 2 2 2 0 IncA protein DUF1311 PF07007.7 EIW73360.1 - 7.3 6.7 9.3 8.7 6.5 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1311) DNA_ligase_A_M PF01068.16 EIW73365.1 - 3.7e-44 150.5 0.0 7.8e-44 149.4 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIW73365.1 - 3.1e-35 121.5 0.0 6.5e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus BRCT PF00533.21 EIW73365.1 - 6.4e-20 71.0 0.2 4.1e-11 42.8 0.0 2.9 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.10 EIW73365.1 - 1.4e-11 44.6 0.0 7.9e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region PTCB-BRCT PF12738.2 EIW73365.1 - 0.00019 21.2 0.0 0.47 10.3 0.0 2.7 2 0 0 2 2 2 2 twin BRCT domain RNA_ligase PF09414.5 EIW73365.1 - 0.0019 18.0 0.0 0.0042 16.9 0.0 1.6 2 0 0 2 2 2 1 RNA ligase Prominin PF05478.6 EIW73366.1 - 0.28 8.6 0.1 0.38 8.2 0.0 1.1 1 0 0 1 1 1 0 Prominin bZIP_1 PF00170.16 EIW73367.1 - 0.0026 17.6 10.1 0.0045 16.9 7.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIW73367.1 - 0.21 11.4 10.9 0.4 10.5 7.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.12 EIW73367.1 - 0.36 11.1 9.3 0.65 10.3 6.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Med28 PF11594.3 EIW73367.1 - 0.37 11.0 5.2 0.55 10.4 3.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 DUF4094 PF13334.1 EIW73367.1 - 0.4 11.0 3.5 0.27 11.6 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) RRM_1 PF00076.17 EIW73371.1 - 1.1e-08 34.5 0.0 2.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.17 EIW73371.1 - 1.7e-07 30.8 0.0 3.9e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EIW73371.1 - 1.3e-06 28.2 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW73371.1 - 0.004 16.9 0.1 0.0084 15.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) vWA-TerF-like PF10138.4 EIW73372.1 - 3.7e-08 33.4 0.1 5.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EIW73372.1 - 0.011 15.8 0.2 0.046 13.8 0.1 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain Vac_Fusion PF02346.11 EIW73373.1 - 0.016 14.6 0.2 0.21 11.0 0.0 2.7 3 0 0 3 3 3 0 Chordopoxvirus fusion protein FANCI_S2 PF14676.1 EIW73373.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 2 DivIC PF04977.10 EIW73374.1 - 0.1 12.1 0.7 0.21 11.1 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator RsbRD_N PF14361.1 EIW73375.1 - 0.38 11.2 2.1 1.8 9.0 0.1 2.5 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Latarcin PF10279.4 EIW73376.1 - 0.24 11.6 5.2 0.7 10.1 3.6 1.8 1 0 0 1 1 1 0 Latarcin precursor DUF2587 PF10759.4 EIW73378.1 - 0.031 13.6 0.1 0.12 11.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Nop14 PF04147.7 EIW73378.1 - 5.6 4.7 5.8 8.1 4.2 4.0 1.1 1 0 0 1 1 1 0 Nop14-like family UCH PF00443.24 EIW73379.1 - 1.5e-10 40.6 0.0 4.3e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MULE PF10551.4 EIW73379.1 - 1.1e-05 25.4 0.8 0.00067 19.7 0.1 2.9 2 1 0 2 2 2 1 MULE transposase domain Peptidase_C1_2 PF03051.10 EIW73380.1 - 5.4e-149 496.4 0.0 6.1e-149 496.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EIW73380.1 - 0.00017 21.5 0.0 0.021 14.7 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.8 EIW73380.1 - 0.054 12.0 0.0 0.079 11.4 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein, lambda family adh_short PF00106.20 EIW73381.1 - 5.1e-16 59.0 0.0 6.9e-15 55.3 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW73381.1 - 8.2e-07 29.0 0.0 0.00011 22.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW73381.1 - 1.6e-06 27.9 0.2 5.9e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EIW73381.1 - 0.0038 17.2 0.0 0.1 12.5 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding PNTB PF02233.11 EIW73382.1 - 1.6e-172 574.4 19.8 1.6e-172 574.4 13.7 1.9 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EIW73382.1 - 7.2e-54 181.8 0.3 1.3e-53 181.0 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EIW73382.1 - 7e-39 132.9 0.0 1.3e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EIW73382.1 - 5.8e-30 103.3 2.6 5.8e-30 103.3 1.8 4.6 5 1 0 5 5 5 1 Domain of unknown function (DUF3814) TPP_enzyme_M PF00205.17 EIW73382.1 - 0.00081 19.1 0.1 0.0043 16.8 0.0 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain 2-Hacid_dh_C PF02826.14 EIW73382.1 - 0.00085 18.5 0.1 0.15 11.2 0.0 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EIW73382.1 - 0.0075 15.8 0.1 0.03 13.8 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CPSase_L_chain PF00289.17 EIW73382.1 - 0.015 15.4 0.5 4 7.5 0.1 3.0 2 1 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Pyr_redox_2 PF07992.9 EIW73382.1 - 0.036 13.9 0.3 0.09 12.6 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW73382.1 - 0.043 12.6 0.6 0.067 12.0 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_10 PF13460.1 EIW73382.1 - 0.17 11.8 1.5 17 5.3 0.0 3.0 3 0 0 3 3 3 0 NADH(P)-binding Shikimate_DH PF01488.15 EIW73382.1 - 0.46 10.5 4.5 5.1 7.2 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EIW73384.1 - 4.9e-12 45.7 0.0 6.6e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW73384.1 - 3.1e-11 42.5 0.0 5.3e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW73384.1 - 1.8e-09 36.9 0.0 1.2e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EIW73384.1 - 8.8e-07 29.1 0.1 1e-05 25.6 0.1 2.4 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIW73384.1 - 0.012 14.4 0.0 0.59 8.9 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EIW73384.1 - 0.07 12.0 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain WD40 PF00400.27 EIW73385.1 - 4.6e-53 175.3 24.1 3.1e-11 42.7 0.4 8.1 8 1 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EIW73385.1 - 6e-10 37.8 10.5 0.026 12.6 0.0 5.2 3 1 2 5 5 5 4 Nucleoporin Nup120/160 F-box-like PF12937.2 EIW73385.1 - 1.6e-08 34.1 0.9 1.6e-08 34.1 0.6 2.2 3 0 0 3 3 3 1 F-box-like PQQ_3 PF13570.1 EIW73385.1 - 7.7e-06 26.0 9.7 0.61 10.4 0.1 5.7 6 0 0 6 6 6 2 PQQ-like domain PQQ_2 PF13360.1 EIW73385.1 - 0.00017 21.1 2.4 0.0083 15.6 1.4 3.0 1 1 0 1 1 1 1 PQQ-like domain BBS2_Mid PF14783.1 EIW73385.1 - 0.00052 19.7 0.1 0.61 9.8 0.0 3.7 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region F-box PF00646.28 EIW73385.1 - 0.0048 16.5 0.0 0.015 14.9 0.0 1.9 1 0 0 1 1 1 1 F-box domain Kelch_6 PF13964.1 EIW73385.1 - 0.055 13.6 4.0 25 5.2 0.0 4.7 5 0 0 5 5 5 0 Kelch motif Cytochrom_D1 PF02239.11 EIW73385.1 - 0.082 11.1 0.1 0.53 8.5 0.0 2.2 2 1 0 2 2 2 0 Cytochrome D1 heme domain AAA PF00004.24 EIW73387.1 - 2.6e-48 163.5 0.0 1.2e-41 141.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW73387.1 - 1.3e-07 31.8 0.3 4.7e-06 26.7 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EIW73387.1 - 1.1e-06 28.1 0.0 3.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EIW73387.1 - 1.2e-05 25.2 0.0 3.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EIW73387.1 - 5.1e-05 23.4 0.0 0.0029 17.7 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW73387.1 - 0.00011 21.9 0.0 0.00042 20.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EIW73387.1 - 0.00019 20.8 0.3 0.0011 18.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain Bromodomain PF00439.20 EIW73387.1 - 0.00075 19.3 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_33 PF13671.1 EIW73387.1 - 0.001 18.9 0.0 0.0052 16.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EIW73387.1 - 0.0025 18.6 0.0 0.016 16.0 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EIW73387.1 - 0.0031 17.2 0.8 0.011 15.4 0.1 2.3 2 0 0 2 2 1 1 Part of AAA domain TIP49 PF06068.8 EIW73387.1 - 0.0038 15.9 0.1 0.0099 14.6 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EIW73387.1 - 0.0058 16.6 0.0 0.21 11.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EIW73387.1 - 0.0067 16.4 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EIW73387.1 - 0.007 15.8 0.0 1.8 8.0 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_14 PF13173.1 EIW73387.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW73387.1 - 0.027 14.7 0.0 0.077 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EIW73387.1 - 0.034 13.2 0.1 0.078 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EIW73387.1 - 0.036 14.3 0.0 0.097 12.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 EIW73387.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 1 0 RNA helicase NACHT PF05729.7 EIW73387.1 - 0.072 12.7 0.1 0.22 11.1 0.1 1.9 1 1 0 1 1 1 0 NACHT domain RuvB_N PF05496.7 EIW73387.1 - 0.08 11.9 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EIW73387.1 - 0.085 12.0 0.1 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 EIW73387.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EIW73387.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 EIW73387.1 - 0.13 11.1 0.0 0.43 9.4 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EIW73387.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EIW73387.1 - 0.36 9.6 0.0 25 3.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Cupin_2 PF07883.6 EIW73389.1 - 1.2e-15 56.6 0.4 1.2e-15 56.6 0.3 1.5 2 0 0 2 2 2 1 Cupin domain MannoseP_isomer PF01050.13 EIW73389.1 - 1.1e-05 25.1 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase AraC_binding PF02311.14 EIW73389.1 - 1.2e-05 24.9 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.2 EIW73389.1 - 5.3e-05 22.9 0.1 6e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EIW73389.1 - 0.00028 20.2 0.3 0.00042 19.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 EIW73389.1 - 0.00036 19.9 0.0 0.00039 19.8 0.0 1.1 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EIW73389.1 - 0.0028 17.6 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 ARD/ARD' family GPI PF06560.6 EIW73389.1 - 0.02 13.9 0.1 0.041 12.9 0.0 1.5 1 1 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) DUF22 PF01629.11 EIW73389.1 - 0.052 13.0 0.1 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF22 ArfGap PF01412.13 EIW73390.1 - 1.5e-32 111.8 0.5 7.9e-32 109.4 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf RVP_2 PF08284.6 EIW73391.1 - 0.011 15.6 0.0 0.068 13.1 0.0 2.2 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIW73391.1 - 0.063 13.7 0.0 0.2 12.1 0.0 1.9 1 1 0 1 1 1 0 Aspartyl protease DUF3546 PF12066.3 EIW73393.1 - 3.2e-15 56.0 2.9 5.4e-15 55.3 1.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EIW73393.1 - 3.3e-11 43.7 5.1 1.2e-10 41.9 3.2 2.3 1 1 0 1 1 1 1 Arsenite-resistance protein 2 RRM_1 PF00076.17 EIW73393.1 - 6.7e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.1 EIW73393.1 - 0.0004 19.9 0.0 0.0013 18.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2 PF00096.21 EIW73393.1 - 0.0059 16.8 1.0 0.018 15.3 0.7 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type RRM_6 PF14259.1 EIW73393.1 - 0.03 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.2 EIW73393.1 - 0.033 14.3 0.5 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) NIPSNAP PF07978.8 EIW73394.1 - 1.7e-26 92.1 0.1 1.7e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 NIPSNAP NAD_binding_8 PF13450.1 EIW73400.1 - 1.2e-11 44.4 0.0 4.8e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIW73400.1 - 6e-10 39.1 0.4 2.1e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EIW73400.1 - 6.1e-07 28.6 0.0 0.00037 19.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW73400.1 - 1.1e-05 25.4 0.0 0.00091 19.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW73400.1 - 0.0012 18.9 0.0 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIW73400.1 - 0.0017 17.5 0.0 0.21 10.5 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EIW73400.1 - 0.0077 15.1 0.0 0.037 12.8 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 EIW73400.1 - 0.089 13.2 0.1 1.5 9.3 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF1900 PF08954.6 EIW73401.1 - 2.5e-47 159.8 0.0 2.1e-46 156.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) dUTPase PF00692.14 EIW73401.1 - 1.1e-38 131.6 0.0 2e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 dUTPase WD40 PF00400.27 EIW73401.1 - 1.3e-23 81.9 3.4 5.7e-07 29.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 EIW73401.1 - 1.6e-23 82.0 0.1 2.9e-23 81.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) AAA_2 PF07724.9 EIW73402.1 - 3.5e-36 124.6 0.0 5.3e-27 94.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIW73402.1 - 3.3e-13 49.9 0.0 6.8e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EIW73402.1 - 6.9e-10 38.6 0.0 1.7e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.16 EIW73402.1 - 5.6e-05 22.3 0.0 0.00034 19.8 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIW73402.1 - 0.00018 21.2 0.1 0.00041 20.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIW73402.1 - 0.00028 21.0 0.3 0.0036 17.4 0.2 2.4 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EIW73402.1 - 0.00084 18.8 0.0 0.0041 16.6 0.0 2.2 2 1 0 2 2 1 1 DEAD/DEAH box helicase AAA_17 PF13207.1 EIW73402.1 - 0.00094 19.9 0.0 0.0021 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW73402.1 - 0.0025 17.6 0.0 0.0059 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EIW73402.1 - 0.0027 17.1 0.0 0.01 15.2 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EIW73402.1 - 0.0031 16.9 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.10 EIW73402.1 - 0.0035 17.1 0.0 0.071 12.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EIW73402.1 - 0.0081 15.4 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 EIW73402.1 - 0.011 15.7 0.0 0.04 13.8 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain RuvB_N PF05496.7 EIW73402.1 - 0.02 13.9 0.0 0.068 12.2 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EIW73402.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIW73402.1 - 0.022 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 EIW73402.1 - 0.024 13.5 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EIW73402.1 - 0.025 14.6 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.4 EIW73402.1 - 0.23 10.0 0.0 0.39 9.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MULE PF10551.4 EIW73403.1 - 1.4e-14 54.0 0.1 1.5e-12 47.5 0.1 2.6 1 1 0 1 1 1 1 MULE transposase domain Muted PF14942.1 EIW73404.1 - 0.11 12.4 13.0 0.16 11.8 8.2 1.9 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF1423 PF07227.6 EIW73404.1 - 0.41 9.2 18.2 0.69 8.5 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Hist_deacetyl PF00850.14 EIW73405.1 - 4e-72 243.1 0.1 4.8e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.20 EIW73407.1 - 2.9e-72 242.9 0.0 3.9e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73407.1 - 1e-50 172.2 0.0 1.5e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW73407.1 - 8.1e-05 21.7 0.0 0.00051 19.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like PP2C_2 PF13672.1 EIW73408.1 - 8.5e-11 41.6 0.1 2.1e-10 40.3 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EIW73408.1 - 1.7e-07 31.1 0.0 5.9e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EIW73408.1 - 2.2e-07 30.5 0.0 0.00028 20.3 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C ICL PF00463.16 EIW73409.1 - 3e-236 784.6 0.0 3.4e-236 784.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EIW73409.1 - 1.6e-10 40.5 0.0 2.6e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase RecX PF02631.11 EIW73409.1 - 0.025 14.7 0.1 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 RecX family PT-TG PF14449.1 EIW73409.1 - 0.064 13.0 0.1 0.22 11.3 0.1 1.9 1 0 0 1 1 1 0 Pre-toxin TG Myb_DNA-bind_6 PF13921.1 EIW73411.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Trypan_PARP PF05887.6 EIW73411.1 - 0.37 10.5 11.1 0.56 10.0 7.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mito_carr PF00153.22 EIW73412.1 - 4.2e-62 205.8 0.3 4.1e-23 80.9 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.15 EIW73413.1 - 7.7e-24 84.0 0.0 7.7e-24 84.0 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIW73413.1 - 8.4e-16 59.0 0.0 4e-15 56.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW73413.1 - 3.5e-10 40.3 0.7 8.4e-10 39.1 0.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW73413.1 - 1.2e-06 28.3 0.0 4.7e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIW73413.1 - 9.6e-05 22.0 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase F-box-like PF12937.2 EIW73414.1 - 3.2e-11 42.7 1.6 4.4e-11 42.3 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EIW73414.1 - 6.2e-07 28.8 12.0 0.96 9.7 0.0 7.3 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EIW73414.1 - 2.9e-05 23.5 6.1 2.7 7.6 0.0 5.3 7 0 0 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW73414.1 - 3.5e-05 23.4 11.3 0.17 11.6 0.9 6.5 5 1 3 8 8 8 4 Leucine rich repeat F-box PF00646.28 EIW73414.1 - 0.00035 20.1 2.9 0.0011 18.5 0.0 3.1 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.28 EIW73414.1 - 0.001 18.8 18.9 2.5 8.4 0.1 8.2 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_7 PF13504.1 EIW73414.1 - 0.39 11.1 9.8 18 6.0 0.1 6.2 6 0 0 6 6 6 0 Leucine rich repeat Synaptobrevin PF00957.16 EIW73415.1 - 4.7e-34 115.8 4.1 5.3e-34 115.6 2.9 1.0 1 0 0 1 1 1 1 Synaptobrevin Sec20 PF03908.8 EIW73415.1 - 0.052 13.2 0.1 0.069 12.8 0.1 1.2 1 0 0 1 1 1 0 Sec20 DUF515 PF04415.7 EIW73415.1 - 0.053 11.7 0.3 0.057 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF1705 PF08019.7 EIW73415.1 - 0.073 12.5 0.8 0.1 12.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) NPV_P10 PF05531.7 EIW73415.1 - 0.1 12.8 0.6 0.19 12.0 0.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.19 EIW73415.1 - 2.7 7.6 4.3 7.5 6.2 3.0 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Hus1 PF04005.7 EIW73416.1 - 4.4e-69 232.6 0.0 6.1e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Hus1-like protein Rad1 PF02144.11 EIW73416.1 - 0.0073 15.1 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_C PF02747.10 EIW73416.1 - 0.0095 15.8 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Pet191_N PF10203.4 EIW73417.1 - 1.7e-24 85.6 2.5 2e-24 85.4 1.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EIW73417.1 - 0.21 11.3 2.4 1.2 8.9 0.1 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EIW73417.1 - 0.27 11.2 1.2 4.9 7.1 0.1 2.4 2 0 0 2 2 2 0 CHCH domain DUF3093 PF11292.3 EIW73418.1 - 0.065 13.0 0.1 0.065 13.0 0.1 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) 2CSK_N PF08521.5 EIW73419.1 - 0.064 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal TB2_DP1_HVA22 PF03134.14 EIW73420.1 - 8.5e-09 35.0 0.0 1.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Pantoate_ligase PF02569.10 EIW73420.1 - 0.074 11.8 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase LSM14 PF12701.2 EIW73421.1 - 2.7e-14 52.7 0.0 1.2e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 Scd6-like Sm domain PAT1 PF09770.4 EIW73421.1 - 0.011 14.0 15.5 0.014 13.7 10.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FDF PF09532.5 EIW73421.1 - 0.09 13.3 0.4 0.22 12.0 0.3 1.7 1 1 0 1 1 1 0 FDF domain PAP2 PF01569.16 EIW73422.1 - 2.9e-11 43.1 5.5 2.9e-11 43.1 3.8 1.6 1 1 1 2 2 2 1 PAP2 superfamily Glyco_transf_8 PF01501.15 EIW73425.1 - 3.2e-28 98.7 0.0 4.7e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EIW73425.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative TFIIF_alpha PF05793.7 EIW73425.1 - 2.9 6.1 4.7 4 5.7 3.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glyco_transf_20 PF00982.16 EIW73426.1 - 5.5e-185 615.3 0.0 7.9e-136 453.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 zf-CCCH PF00642.19 EIW73427.1 - 4.7e-05 22.9 2.4 8.7e-05 22.0 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIW73427.1 - 0.43 10.6 2.3 0.86 9.7 1.6 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Pex24p PF06398.6 EIW73427.1 - 0.84 8.3 3.7 1.3 7.7 2.5 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin ARD PF03079.9 EIW73428.1 - 4.5e-45 153.4 0.0 5.3e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EIW73428.1 - 3.9e-09 35.8 0.1 6.8e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EIW73428.1 - 5.8e-07 29.2 0.1 9.2e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EIW73428.1 - 6.7e-06 25.5 0.0 8.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EIW73428.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_8 PF13621.1 EIW73428.1 - 0.032 13.7 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Cupin-like domain Mito_carr PF00153.22 EIW73429.1 - 4e-50 167.4 1.8 1.6e-16 59.8 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein Zw10 PF06248.8 EIW73431.1 - 1.2e-18 66.5 1.1 6.2e-12 44.4 0.0 2.4 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EIW73431.1 - 9.9e-09 34.7 2.1 1.2e-08 34.4 0.2 2.0 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal CTNNBL PF08216.6 EIW73432.1 - 1.7e-25 88.7 0.0 1.7e-24 85.4 0.0 2.6 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Neurochondrin PF05536.6 EIW73432.1 - 0.00055 18.3 0.1 0.0011 17.4 0.0 1.4 1 0 0 1 1 1 1 Neurochondrin Arm PF00514.18 EIW73432.1 - 0.014 15.1 0.1 0.25 11.2 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Rrn6 PF10214.4 EIW73433.1 - 7.4e-22 77.2 0.0 5.3e-13 47.9 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor MFS_1 PF07690.11 EIW73434.1 - 3.2e-26 91.8 19.8 3.2e-26 91.8 13.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1049 PF06305.6 EIW73434.1 - 0.26 10.7 1.4 0.94 8.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Amidase PF01425.16 EIW73435.1 - 1.9e-99 333.5 0.0 2.4e-99 333.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Alpha-amylase PF00128.19 EIW73436.1 - 6.5e-49 167.0 0.0 9.8e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EIW73436.1 - 1.8e-16 60.0 0.1 6e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Gin PF10764.4 EIW73437.1 - 3 7.6 5.2 16 5.3 0.1 2.7 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin zf-CCHC PF00098.18 EIW73438.1 - 0.0037 17.1 1.9 0.0081 16.0 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Herpes_US9 PF06072.6 EIW73443.1 - 0.2 11.5 2.8 0.5 10.2 0.4 2.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 AlphaC_N PF08829.5 EIW73444.1 - 0.038 13.3 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal DUF1877 PF08974.5 EIW73444.1 - 0.13 11.9 0.9 0.26 10.9 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) DUF2076 PF09849.4 EIW73447.1 - 0.052 13.5 0.5 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ins_P5_2-kin PF06090.7 EIW73448.1 - 8.2e-51 172.8 0.0 2e-50 171.6 0.0 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Glyco_transf_90 PF05686.7 EIW73449.1 - 6.2e-16 58.0 0.0 1.5e-14 53.5 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 90 AAA PF00004.24 EIW73450.1 - 2.1e-38 131.5 0.0 3.3e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIW73450.1 - 1e-05 24.6 0.0 2.4e-05 23.5 0.0 1.5 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIW73450.1 - 1.8e-05 24.8 0.2 0.0012 18.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW73450.1 - 3.3e-05 24.0 0.2 0.0021 18.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW73450.1 - 4.8e-05 23.1 0.2 0.00065 19.4 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIW73450.1 - 5.9e-05 22.9 0.0 0.00016 21.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EIW73450.1 - 7.8e-05 22.5 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW73450.1 - 0.00029 20.0 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EIW73450.1 - 0.00048 20.9 0.0 0.00085 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EIW73450.1 - 0.0012 18.3 0.0 0.014 14.8 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EIW73450.1 - 0.0014 18.0 0.5 0.086 12.2 0.1 2.3 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIW73450.1 - 0.0017 17.5 0.1 0.0088 15.2 0.1 2.0 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EIW73450.1 - 0.0029 17.6 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_2 PF07724.9 EIW73450.1 - 0.0037 17.2 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EIW73450.1 - 0.0037 16.7 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 EIW73450.1 - 0.0038 16.8 0.2 0.018 14.7 0.1 2.0 2 0 0 2 2 2 1 NACHT domain KaiC PF06745.8 EIW73450.1 - 0.0038 16.3 0.0 0.16 11.0 0.0 2.2 1 1 1 2 2 2 1 KaiC RNA_helicase PF00910.17 EIW73450.1 - 0.0044 17.1 0.0 0.0095 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.8 EIW73450.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 EIW73450.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EIW73450.1 - 0.015 15.5 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EIW73450.1 - 0.017 13.8 0.1 0.034 12.8 0.0 1.4 1 1 0 1 1 1 0 TIP49 C-terminus UPF0079 PF02367.12 EIW73450.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EIW73450.1 - 0.026 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW73450.1 - 0.029 14.6 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EIW73450.1 - 0.032 14.1 0.1 0.082 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EIW73450.1 - 0.045 13.3 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.17 EIW73450.1 - 0.061 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain SKI PF01202.17 EIW73450.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase Rad17 PF03215.10 EIW73450.1 - 0.084 11.5 0.1 0.17 10.5 0.1 1.5 1 1 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 EIW73450.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 EIW73450.1 - 0.12 11.8 0.1 0.74 9.2 0.1 1.9 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Parvo_NS1 PF01057.12 EIW73450.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Pkinase PF00069.20 EIW73451.1 - 1.6e-69 233.9 0.0 2e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73451.1 - 7.1e-44 149.8 0.0 9.1e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW73451.1 - 1.3e-08 34.1 0.0 5.6e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 EIW73451.1 - 0.003 16.9 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EIW73451.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW73451.1 - 0.08 12.6 0.1 0.68 9.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nucleoplasmin PF03066.10 EIW73452.1 - 0.0026 17.2 8.8 0.0051 16.3 2.3 2.3 2 0 0 2 2 2 1 Nucleoplasmin CENP-B_dimeris PF09026.5 EIW73452.1 - 0.74 10.0 12.9 6.1 7.1 6.6 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 EIW73452.1 - 4.1 7.1 12.2 4.1 7.1 2.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Gag_spuma PF03276.9 EIW73452.1 - 5 5.3 8.0 7.6 4.7 5.6 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Sporozoite_P67 PF05642.6 EIW73452.1 - 6.6 4.4 16.1 17 3.1 11.1 1.6 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DUF1700 PF08006.6 EIW73453.1 - 0.027 13.7 4.7 0.04 13.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Las1 PF04031.8 EIW73454.1 - 1.9e-35 121.7 0.0 4.3e-35 120.6 0.0 1.6 1 0 0 1 1 1 1 Las1-like DUF4048 PF13257.1 EIW73454.1 - 0.0011 18.6 0.2 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4048) Moulting_cycle PF04870.11 EIW73454.1 - 0.72 8.8 6.6 0.55 9.2 1.0 2.1 2 0 0 2 2 2 0 Moulting cycle Y_phosphatase2 PF03162.8 EIW73459.1 - 2.3e-38 131.1 0.0 3.1e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family zf-Tim10_DDP PF02953.10 EIW73460.1 - 2.1e-21 74.9 0.4 2.4e-21 74.7 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Rhodanese PF00581.15 EIW73461.1 - 2.6e-15 56.7 0.0 1.7e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Adaptin_N PF01602.15 EIW73462.1 - 1.1e-109 367.2 7.3 1.5e-109 366.7 5.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EIW73462.1 - 4.8e-58 195.2 0.0 1.1e-57 194.0 0.0 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EIW73462.1 - 4.3e-16 58.9 3.9 0.00013 22.2 0.0 6.1 3 2 2 6 6 6 4 HEAT repeats Cnd1 PF12717.2 EIW73462.1 - 0.0073 16.1 10.5 9.4 6.0 0.2 4.7 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EIW73462.1 - 0.0095 15.9 11.7 2.8 8.2 0.1 6.9 8 1 1 9 9 9 1 HEAT repeat HEAT_PBS PF03130.11 EIW73462.1 - 0.055 13.9 1.1 53 4.7 0.0 5.0 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EIW73462.1 - 0.069 13.6 2.5 44 4.7 0.0 4.6 5 1 0 5 5 5 0 HEAT-like repeat Beta_helix PF13229.1 EIW73463.1 - 4.3e-09 36.3 27.8 8e-06 25.6 19.0 2.6 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 EIW73463.1 - 7.6e-07 28.5 11.8 0.00018 20.7 2.7 2.4 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) SMC_N PF02463.14 EIW73465.1 - 1.9e-29 102.4 0.0 4.7e-29 101.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EIW73465.1 - 6.7e-10 39.6 13.2 6.7e-10 39.6 9.2 6.7 6 1 0 6 6 6 1 AAA domain AAA_29 PF13555.1 EIW73465.1 - 0.00034 20.0 0.0 0.00094 18.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EIW73465.1 - 0.00064 19.7 0.1 0.0029 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain FHIPEP PF00771.15 EIW73465.1 - 0.0028 16.0 0.1 0.0028 16.0 0.0 3.9 4 0 0 4 4 4 1 FHIPEP family TerC PF03741.11 EIW73465.1 - 0.035 13.5 0.1 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Integral membrane protein TerC family DUF1616 PF07760.6 EIW73465.1 - 0.24 10.4 0.1 0.58 9.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) FliP PF00813.15 EIW73465.1 - 4.7 6.8 8.8 1.6 8.3 0.0 3.3 3 0 0 3 3 3 0 FliP family Lon_C PF05362.8 EIW73466.1 - 5.1e-67 225.1 0.1 8.5e-67 224.4 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EIW73466.1 - 2.8e-35 121.8 2.2 2.8e-35 121.8 1.5 2.6 2 1 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EIW73466.1 - 9e-22 77.6 0.0 3.7e-21 75.7 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EIW73466.1 - 4.9e-08 32.5 0.1 1.9e-07 30.6 0.1 2.0 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EIW73466.1 - 2.7e-07 30.3 0.0 5.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIW73466.1 - 1e-06 28.7 0.1 1.2e-05 25.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EIW73466.1 - 9.2e-06 26.4 0.4 6.6e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW73466.1 - 3.4e-05 23.9 0.1 0.00025 21.0 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain AAA_PrkA PF08298.6 EIW73466.1 - 3.6e-05 22.6 0.0 7.8e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.7 EIW73466.1 - 0.00038 19.5 0.0 0.0015 17.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EIW73466.1 - 0.00065 20.0 2.2 0.0031 17.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIW73466.1 - 0.0014 18.8 0.2 0.025 14.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIW73466.1 - 0.0031 17.3 0.0 0.013 15.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EIW73466.1 - 0.019 14.4 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.17 EIW73466.1 - 0.021 14.7 0.1 0.061 13.1 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase AAA_3 PF07726.6 EIW73466.1 - 0.027 14.0 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EIW73466.1 - 0.03 14.5 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 1 0 RNA helicase UPF0079 PF02367.12 EIW73466.1 - 0.031 13.9 0.1 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EIW73466.1 - 0.04 13.3 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW73466.1 - 0.043 13.0 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EIW73466.1 - 0.056 12.8 0.4 5.4 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain APS_kinase PF01583.15 EIW73466.1 - 0.071 12.7 0.4 20 4.7 0.0 3.4 4 0 0 4 4 3 0 Adenylylsulphate kinase AAA_24 PF13479.1 EIW73466.1 - 0.072 12.6 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIW73466.1 - 0.098 12.3 3.6 28 4.3 0.0 3.5 2 1 1 3 3 3 0 Archaeal ATPase Pex14_N PF04695.8 EIW73466.1 - 0.13 12.3 10.0 0.022 14.8 3.8 1.9 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_33 PF13671.1 EIW73466.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIW73466.1 - 0.28 11.4 0.0 0.28 11.4 0.0 3.0 2 1 0 2 2 1 0 AAA domain TIP49 PF06068.8 EIW73466.1 - 0.77 8.4 5.7 0.089 11.4 0.1 2.2 3 0 0 3 3 3 0 TIP49 C-terminus GRIP PF01465.15 EIW73468.1 - 3.6e-17 61.5 0.8 7.9e-17 60.5 0.5 1.6 1 0 0 1 1 1 1 GRIP domain Snf7 PF03357.16 EIW73469.1 - 3.1e-31 108.0 13.7 3.6e-31 107.8 9.5 1.0 1 0 0 1 1 1 1 Snf7 Acetyltransf_1 PF00583.19 EIW73470.1 - 1.4e-08 34.6 0.0 2.7e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW73470.1 - 0.00076 19.6 0.0 0.0021 18.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW73470.1 - 0.043 13.9 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Macoilin PF09726.4 EIW73471.1 - 0.025 12.8 16.1 0.03 12.6 11.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Gly-zipper_OmpA PF13436.1 EIW73471.1 - 0.07 12.8 4.5 0.14 11.8 0.4 2.7 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain SLD3 PF08639.5 EIW73471.1 - 0.94 8.0 15.2 1.2 7.7 10.5 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 zf-CCHC PF00098.18 EIW73474.1 - 0.00074 19.3 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle BRF1 PF07741.8 EIW73474.1 - 0.44 10.8 7.2 0.12 12.6 2.8 1.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Radial_spoke_3 PF06098.6 EIW73474.1 - 0.45 9.4 7.7 0.97 8.3 2.4 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 B56 PF01603.15 EIW73474.1 - 0.84 8.1 2.8 1.1 7.7 1.9 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) zf-CCHC PF00098.18 EIW73475.1 - 0.00097 18.9 1.8 0.0015 18.3 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIW73475.1 - 0.011 15.2 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle BRF1 PF07741.8 EIW73475.1 - 0.013 15.6 4.5 0.023 14.8 3.1 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Atrophin-1 PF03154.10 EIW73475.1 - 3.5 5.6 9.2 5.6 4.9 2.9 2.0 2 0 0 2 2 2 0 Atrophin-1 family zf-CCHC_5 PF14787.1 EIW73475.1 - 6.7 6.2 7.8 0.81 9.2 1.7 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger TPR_15 PF13429.1 EIW73477.1 - 0.15 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat RVT_1 PF00078.22 EIW73479.1 - 2.7e-22 79.2 0.2 2.1e-21 76.2 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EIW73479.1 - 1.3e-18 67.1 0.0 4.1e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIW73479.1 - 3.3e-08 33.0 0.1 1e-07 31.5 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3818 PF12825.2 EIW73479.1 - 0.14 10.8 0.0 0.24 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) zf-CCHC PF00098.18 EIW73480.1 - 0.002 17.9 1.9 0.0039 17.0 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW73480.1 - 0.051 13.3 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Acetyltransf_3 PF13302.1 EIW73481.1 - 1.8e-06 28.1 0.0 4.3e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW73482.1 - 4.7e-07 30.0 0.0 9e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW73482.1 - 0.026 14.4 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RNA_lig_T4_1 PF09511.5 EIW73483.1 - 9.2e-81 270.5 0.0 2.6e-80 269.0 0.0 1.7 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 EIW73483.1 - 8e-25 87.6 0.0 1.6e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 EIW73483.1 - 1.5e-11 43.9 0.0 3.6e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_17 PF13207.1 EIW73483.1 - 0.087 13.6 0.0 0.27 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain MSP1_C PF07462.6 EIW73484.1 - 1 7.6 3.1 1.8 6.8 2.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Vac14_Fig4_bd PF11916.3 EIW73485.1 - 2.4e-78 261.4 5.2 4.4e-78 260.5 3.6 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EIW73485.1 - 1.5e-45 153.4 0.0 3.2e-41 139.6 0.0 4.2 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EIW73485.1 - 6.1e-12 44.5 2.1 1e-05 25.1 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EIW73485.1 - 1.6e-09 37.8 2.5 0.0012 19.0 0.0 4.4 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EIW73485.1 - 9.9e-08 32.2 1.0 0.00093 19.6 0.0 5.3 4 1 1 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 EIW73485.1 - 0.00028 20.8 0.7 0.57 10.0 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EIW73485.1 - 0.012 15.4 0.0 8.9 6.3 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat FTR1 PF03239.9 EIW73487.1 - 3.9e-66 223.0 7.2 4.4e-66 222.9 5.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Herpes_glycop PF01528.11 EIW73487.1 - 0.016 13.8 0.1 0.016 13.8 0.1 2.4 3 0 0 3 3 3 0 Herpesvirus glycoprotein M DUF3592 PF12158.3 EIW73487.1 - 0.34 10.6 0.0 0.34 10.6 0.0 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3592) Yip1 PF04893.12 EIW73487.1 - 0.45 10.0 27.5 1 8.8 2.7 3.3 3 0 0 3 3 3 0 Yip1 domain BPD_transp_2 PF02653.11 EIW73487.1 - 6.9 5.5 28.1 0.1 11.5 0.3 2.7 3 1 0 3 3 3 0 Branched-chain amino acid transport system / permease component bZIP_1 PF00170.16 EIW73488.1 - 8.8e-06 25.5 12.2 0.00019 21.3 2.5 3.0 3 0 0 3 3 3 2 bZIP transcription factor Hap4_Hap_bind PF10297.4 EIW73488.1 - 1.3e-05 24.9 2.7 1.3e-05 24.9 1.9 2.2 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 HALZ PF02183.13 EIW73488.1 - 0.01 15.5 2.6 0.036 13.7 1.0 2.2 2 0 0 2 2 2 1 Homeobox associated leucine zipper TSC22 PF01166.13 EIW73488.1 - 0.035 14.0 0.2 5.1 7.1 0.0 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.7 EIW73488.1 - 0.084 12.6 6.9 0.17 11.6 4.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein RmuC PF02646.11 EIW73488.1 - 0.12 11.1 2.6 0.19 10.5 1.8 1.3 1 0 0 1 1 1 0 RmuC family LRR_4 PF12799.2 EIW73489.1 - 5.6e-37 124.7 36.4 3.9e-11 42.3 2.6 7.0 4 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW73489.1 - 4.2e-27 93.6 21.9 5.3e-10 38.8 0.1 5.5 2 2 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.1 EIW73489.1 - 8.4e-17 61.2 6.6 3.7e-08 33.1 0.2 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 EIW73489.1 - 9.9e-16 55.3 31.4 0.29 11.3 0.0 11.4 12 0 0 12 12 12 7 Leucine Rich Repeat LRR_6 PF13516.1 EIW73489.1 - 1.1e-10 40.4 29.3 0.076 13.1 0.1 10.8 10 2 1 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 EIW73489.1 - 5.7e-08 31.7 20.6 3.5 8.2 0.0 10.2 10 1 0 10 10 10 3 Leucine rich repeat LRR_2 PF07723.8 EIW73489.1 - 0.05 14.1 2.5 3.4 8.3 0.0 4.3 4 1 1 5 5 5 0 Leucine Rich Repeat Gly_transf_sug PF04488.10 EIW73490.1 - 3.3e-11 43.4 0.0 6.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif cobW PF02492.14 EIW73491.1 - 2.5e-40 137.8 0.0 3.2e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EIW73491.1 - 0.0012 18.3 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EIW73491.1 - 0.0015 18.0 0.1 0.073 12.4 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain CobW_C PF07683.9 EIW73491.1 - 0.002 17.8 0.0 0.0046 16.6 0.0 1.6 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_10 PF12846.2 EIW73491.1 - 0.0047 16.4 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain ArgK PF03308.11 EIW73491.1 - 0.041 12.6 0.0 0.77 8.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_23 PF13476.1 EIW73491.1 - 0.042 14.1 0.0 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EIW73491.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Zip PF02535.17 EIW73491.1 - 1.6 7.6 4.2 2.1 7.2 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter W2 PF02020.13 EIW73492.1 - 3e-18 65.5 1.0 1.2e-17 63.6 0.0 2.4 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon FAD_binding_4 PF01565.18 EIW73493.1 - 6.8e-20 70.9 2.4 5.1e-09 35.7 0.1 2.8 3 0 0 3 3 3 2 FAD binding domain BBE PF08031.7 EIW73493.1 - 7.8e-07 28.9 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF605 PF04652.11 EIW73493.1 - 1.4 8.2 6.3 1.9 7.7 4.3 1.1 1 0 0 1 1 1 0 Vta1 like Isy1 PF06246.7 EIW73494.1 - 9.3e-78 261.1 0.0 1.1e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 Isy1-like splicing family CCDC-167 PF15188.1 EIW73494.1 - 0.12 12.3 0.1 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 HECT PF00632.20 EIW73497.1 - 1.9e-76 257.2 0.0 2.9e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EIW73497.1 - 0.0013 18.5 2.4 4 7.4 0.0 4.4 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat His_Phos_1 PF00300.17 EIW73498.1 - 1.3e-15 57.8 0.0 1.7e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) VTC PF09359.5 EIW73499.1 - 5.6e-95 317.5 0.1 1e-94 316.7 0.0 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EIW73499.1 - 2e-27 96.6 10.8 5.9e-20 72.1 0.1 3.2 2 2 2 4 4 4 2 SPX domain DUF202 PF02656.10 EIW73499.1 - 1.2e-07 31.7 1.2 1.2e-07 31.7 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1154 PF06631.6 EIW73499.1 - 0.029 14.0 3.3 1.2 8.8 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) HALZ PF02183.13 EIW73499.1 - 0.049 13.3 0.6 0.22 11.2 0.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Iso_dh PF00180.15 EIW73500.1 - 1.4e-89 300.4 0.0 2.5e-89 299.6 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Med4 PF10018.4 EIW73501.1 - 1.8e-24 86.2 1.9 1.8e-24 86.2 1.3 1.4 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Sec8_exocyst PF04048.9 EIW73501.1 - 0.034 13.7 0.1 0.071 12.7 0.1 1.6 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain Syntaxin_2 PF14523.1 EIW73501.1 - 0.041 13.9 5.3 0.22 11.5 2.8 2.2 1 1 1 2 2 2 0 Syntaxin-like protein CCDC-167 PF15188.1 EIW73501.1 - 0.05 13.5 1.1 0.097 12.6 0.8 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 GAS PF13851.1 EIW73501.1 - 0.068 12.3 3.1 0.73 8.9 2.0 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Taxilin PF09728.4 EIW73501.1 - 0.1 11.6 2.7 0.13 11.3 1.9 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF3563 PF12086.3 EIW73501.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) HAD PF12710.2 EIW73502.1 - 2.8e-14 53.7 0.0 4e-13 49.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW73502.1 - 6.1e-12 46.4 0.2 2e-09 38.2 0.1 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW73502.1 - 1.2e-11 44.4 0.0 3.1e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EIW73502.1 - 4.9e-10 38.8 0.0 4.9e-10 38.8 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.7 EIW73502.1 - 0.00052 19.6 0.1 0.012 15.1 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIW73502.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TPR_19 PF14559.1 EIW73503.1 - 0.0074 16.6 0.0 0.029 14.7 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat PPR_2 PF13041.1 EIW73503.1 - 0.022 14.7 0.0 0.12 12.3 0.0 2.3 1 1 1 2 2 2 0 PPR repeat family SET PF00856.23 EIW73505.1 - 3.9e-23 82.5 0.2 1.8e-22 80.3 0.1 1.9 1 1 0 1 1 1 1 SET domain Response_reg PF00072.19 EIW73506.1 - 2.8e-21 75.6 0.6 8.3e-20 70.8 0.1 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EIW73506.1 - 4.3e-12 45.7 0.0 7.9e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EIW73506.1 - 7.2e-06 25.9 0.1 2e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Ribosomal_S17 PF00366.15 EIW73506.1 - 2.9 7.9 4.8 98 3.1 0.0 5.1 4 1 3 7 7 7 0 Ribosomal protein S17 WD40 PF00400.27 EIW73507.1 - 4.6e-54 178.4 21.0 3.4e-09 36.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIW73507.1 - 0.0021 17.7 0.0 1.7 8.2 0.0 2.6 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW73507.1 - 0.13 10.3 0.4 3 5.8 0.1 2.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Polysacc_deac_1 PF01522.16 EIW73508.1 - 1.7e-22 79.3 0.0 3.2e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glucosamine_iso PF01182.15 EIW73509.1 - 4.1e-54 183.3 0.2 9.8e-54 182.0 0.0 1.6 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase tRNA-synt_2 PF00152.15 EIW73510.1 - 1.6e-58 198.1 0.0 2e-45 155.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIW73510.1 - 7e-12 45.0 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EIW73510.1 - 0.074 12.6 0.0 9.6 5.7 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) PHD PF00628.24 EIW73511.1 - 8.5e-11 41.3 9.2 1.5e-10 40.6 6.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EIW73511.1 - 0.016 14.5 2.9 0.028 13.7 2.0 1.4 1 0 0 1 1 1 0 PHD-finger UPF0160 PF03690.8 EIW73512.1 - 2.8e-127 424.5 0.0 3.2e-127 424.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) GTP_CH_N PF12471.3 EIW73512.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.6 2 0 0 2 2 2 0 GTP cyclohydrolase N terminal Smr PF01713.16 EIW73515.1 - 1.8e-10 40.8 0.0 4e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 EIW73515.1 - 0.0028 17.1 0.5 0.058 12.8 0.0 2.7 2 0 0 2 2 2 1 CUE domain CotH PF08757.6 EIW73515.1 - 0.05 12.8 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 CotH protein Bystin PF05291.6 EIW73516.1 - 5.9e-126 419.4 0.0 8.4e-126 418.9 0.0 1.2 1 0 0 1 1 1 1 Bystin HMG_box_2 PF09011.5 EIW73517.1 - 0.022 15.1 5.2 0.03 14.7 3.6 1.3 1 0 0 1 1 1 0 HMG-box domain DUF1014 PF06244.7 EIW73517.1 - 0.028 14.6 5.1 0.032 14.4 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) YABBY PF04690.8 EIW73517.1 - 0.036 14.3 0.7 0.037 14.2 0.5 1.1 1 0 0 1 1 1 0 YABBY protein DUF2852 PF11014.3 EIW73517.1 - 0.059 13.3 0.6 0.065 13.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF2913 PF11140.3 EIW73517.1 - 0.2 10.9 2.4 0.23 10.7 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) MatE PF01554.13 EIW73518.1 - 3.3e-49 166.6 24.2 8.8e-26 90.4 5.6 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EIW73518.1 - 1.2e-09 38.1 6.9 1.2e-09 38.1 4.8 3.5 3 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain RhoGEF PF00621.15 EIW73519.1 - 2e-48 164.6 0.0 3.6e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 EIW73519.1 - 1.9e-10 40.1 0.1 6.6e-05 22.4 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW73519.1 - 4.4e-07 29.5 0.2 0.0027 17.4 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EIW73519.1 - 4.8e-05 22.8 1.2 0.096 12.7 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 EIW73519.1 - 0.006 16.5 2.1 12 6.6 0.0 4.3 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 EIW73519.1 - 0.01 15.8 0.2 0.97 9.7 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat QRPTase_C PF01729.14 EIW73520.1 - 5.8e-49 165.8 0.1 7.1e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EIW73520.1 - 1.2e-19 69.8 0.0 3.9e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF4449 PF14613.1 EIW73522.1 - 3.3e-07 30.3 11.2 1.3e-05 25.1 0.0 4.4 3 1 1 4 4 4 2 Protein of unknown function (DUF4449) S_100 PF01023.14 EIW73522.1 - 0.036 13.3 0.0 0.1 11.9 0.0 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Ribonuc_L-PSP PF01042.16 EIW73522.1 - 0.043 13.5 0.1 1.4 8.7 0.0 3.1 3 0 0 3 3 3 0 Endoribonuclease L-PSP HD_4 PF13328.1 EIW73523.1 - 6.8e-30 103.8 0.0 9e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 EIW73523.1 - 0.00023 21.1 0.1 0.00062 19.7 0.0 1.7 1 1 0 1 1 1 1 HD domain Ham1p_like PF01725.11 EIW73523.1 - 0.095 12.0 0.0 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Ham1 family Coatomer_E PF04733.9 EIW73525.1 - 5.7e-34 117.6 0.0 7.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit LRV PF01816.12 EIW73525.1 - 6.6 7.1 6.9 0.37 11.0 0.7 2.2 2 0 0 2 2 2 0 Leucine rich repeat variant Abhydrolase_6 PF12697.2 EIW73526.1 - 1.1e-16 61.4 1.5 1.1e-16 61.4 1.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW73526.1 - 7.6e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW73526.1 - 9.2e-05 22.2 0.1 0.00035 20.3 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW73526.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family PH_4 PF15404.1 EIW73527.1 - 1.5e-24 86.5 1.6 1.5e-21 76.7 1.1 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIW73527.1 - 6.9e-08 32.6 0.3 0.07 13.3 0.0 3.8 3 1 0 3 3 3 2 PH domain Phosducin PF02114.11 EIW73527.1 - 0.049 12.3 0.0 0.49 9.0 0.0 2.1 2 0 0 2 2 2 0 Phosducin PH_6 PF15406.1 EIW73527.1 - 0.21 11.6 0.4 26 4.9 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain Glyco_hydro_2 PF00703.16 EIW73529.1 - 1.7e-09 38.0 0.3 3.7e-09 37.0 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EIW73529.1 - 0.00047 19.7 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EIW73529.1 - 0.00077 18.4 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4210 PF13915.1 EIW73530.1 - 2.2e-07 31.0 0.0 2.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Kelch_4 PF13418.1 EIW73531.1 - 2.4e-14 52.7 4.7 4.3e-08 32.7 0.1 4.5 3 2 1 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EIW73531.1 - 2.1e-09 37.1 1.5 0.014 15.3 0.0 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 EIW73531.1 - 8.1e-07 28.9 7.2 9.7e-05 22.3 0.1 4.0 3 2 2 5 5 5 2 Kelch motif Kelch_1 PF01344.20 EIW73531.1 - 1e-06 28.1 0.0 0.00036 20.0 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 EIW73531.1 - 2.1e-06 27.7 12.2 0.0022 18.0 0.1 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EIW73531.1 - 0.031 14.0 0.2 1.9 8.4 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Ribosomal_L18e PF00828.14 EIW73532.1 - 5.2e-23 81.8 0.5 6.7e-23 81.4 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 SAP PF02037.22 EIW73533.1 - 8.1e-10 37.9 0.4 2.2e-09 36.6 0.3 1.7 1 0 0 1 1 1 1 SAP domain DDA1 PF10172.4 EIW73533.1 - 0.09 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase Prenyltransf PF01255.14 EIW73534.1 - 3.2e-62 209.5 0.0 1.7e-40 138.5 0.0 2.1 1 1 1 2 2 2 2 Putative undecaprenyl diphosphate synthase AP_endonuc_2 PF01261.19 EIW73534.1 - 0.049 12.9 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HypD PF01924.11 EIW73534.1 - 0.18 10.4 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family Evr1_Alr PF04777.8 EIW73535.1 - 6.5e-28 96.4 0.5 1.2e-27 95.5 0.0 1.6 2 0 0 2 2 2 1 Erv1 / Alr family DUF2798 PF11391.3 EIW73537.1 - 0.15 11.7 2.1 15 5.4 2.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2798) RVT_2 PF07727.9 EIW73540.1 - 2e-10 40.0 0.0 3.1e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Alpha_kinase PF02816.13 EIW73541.1 - 6.2e-11 42.3 0.5 9.3e-11 41.7 0.4 1.3 1 0 0 1 1 1 1 Alpha-kinase family Extensin-like_C PF06904.7 EIW73543.1 - 0.095 12.4 0.2 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Extensin-like protein C-terminus CesA PF11439.3 EIW73544.1 - 0.022 14.6 0.1 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA DUF1323 PF07037.6 EIW73544.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative transcription regulator (DUF1323) DUF4041 PF13250.1 EIW73544.1 - 0.14 11.7 0.6 0.22 11.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) DWNN PF08783.6 EIW73545.1 - 4.2e-28 97.0 0.0 7.1e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EIW73545.1 - 1.7e-05 24.2 2.0 3.3e-05 23.2 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EIW73545.1 - 0.00018 21.2 2.5 0.00018 21.2 1.7 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EIW73545.1 - 0.00049 20.0 13.5 0.00049 20.0 9.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 EIW73545.1 - 0.0015 18.2 0.4 0.0044 16.7 0.3 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_3 PF13920.1 EIW73545.1 - 0.004 16.7 9.2 0.004 16.7 6.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW73545.1 - 0.42 10.3 13.2 0.87 9.3 9.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW73545.1 - 2 8.3 19.8 0.034 13.9 8.8 1.8 2 0 0 2 2 2 0 Ring finger domain ArgJ PF01960.13 EIW73546.1 - 1.1e-145 484.9 0.0 1.3e-145 484.7 0.0 1.0 1 0 0 1 1 1 1 ArgJ family PCRF PF03462.13 EIW73546.1 - 0.1 12.2 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 PCRF domain Ebp2 PF05890.7 EIW73548.1 - 2.4e-66 223.8 5.2 2.4e-66 223.8 3.6 1.6 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Sorb PF02208.11 EIW73548.1 - 0.18 11.1 0.7 8.7 5.8 0.1 2.6 2 0 0 2 2 2 0 Sorbin homologous domain DCA16 PF15349.1 EIW73548.1 - 0.55 9.5 3.2 0.81 9.0 2.2 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 RNA_pol_Rpb2_6 PF00562.23 EIW73549.1 - 2.1e-127 425.0 0.6 3.4e-127 424.3 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIW73549.1 - 7.2e-62 207.9 0.0 1.2e-61 207.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EIW73549.1 - 5.9e-41 139.9 0.0 1.1e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EIW73549.1 - 3.2e-30 104.1 0.1 7.4e-30 103.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EIW73549.1 - 2.1e-23 81.8 0.0 5.4e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EIW73549.1 - 1.2e-21 76.2 0.3 2.9e-21 75.0 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EIW73549.1 - 4.8e-15 55.2 0.1 1e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF1886 PF09171.5 EIW73549.1 - 0.096 11.6 0.1 0.18 10.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) NAD_binding_10 PF13460.1 EIW73550.1 - 9.7e-10 38.7 0.0 1e-08 35.3 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW73550.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CcoS PF03597.10 EIW73554.1 - 7.1 6.1 10.0 0.04 13.3 0.9 1.7 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Rax2 PF12768.2 EIW73555.1 - 8.5e-78 261.4 31.3 1.5e-61 208.0 1.1 6.5 5 2 1 6 6 6 5 Cortical protein marker for cell polarity SH3_1 PF00018.23 EIW73555.1 - 4.1e-10 38.8 0.1 8.9e-10 37.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW73555.1 - 1.9e-07 30.5 0.1 6.3e-07 28.8 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW73555.1 - 0.00031 20.1 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pex19 PF04614.7 EIW73556.1 - 4.8e-43 147.5 2.5 6.2e-43 147.2 1.7 1.1 1 0 0 1 1 1 1 Pex19 protein family RNA_pol_Rpb1_5 PF04998.12 EIW73557.1 - 3.4e-89 298.8 0.0 1.3e-88 296.9 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EIW73557.1 - 2.3e-63 213.1 0.2 4.7e-63 212.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIW73557.1 - 1.3e-35 122.4 0.0 4.6e-35 120.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EIW73557.1 - 5.6e-24 85.0 4.7 1.4e-19 70.5 0.0 4.3 4 1 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EIW73557.1 - 1.6e-22 79.2 0.0 6.4e-22 77.3 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 BAR PF03114.13 EIW73558.1 - 8e-42 143.3 1.3 1.1e-41 142.9 0.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EIW73558.1 - 2.6e-12 46.1 0.0 4.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW73558.1 - 6.2e-12 44.7 0.0 1.4e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIW73558.1 - 1.1e-10 40.8 0.0 2.2e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_2 PF10455.4 EIW73558.1 - 5e-05 22.3 3.8 8.8e-05 21.5 2.6 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF2408 PF10303.4 EIW73558.1 - 0.016 15.3 1.1 0.044 13.8 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ABC2_membrane PF01061.19 EIW73559.1 - 3.2e-33 114.6 15.7 3.2e-33 114.6 10.9 3.4 4 0 0 4 4 4 1 ABC-2 type transporter ABC_tran PF00005.22 EIW73559.1 - 6.1e-26 91.3 0.0 1.2e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW73559.1 - 1.6e-08 34.8 1.8 5.8e-06 26.4 1.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIW73559.1 - 5.2e-05 22.7 0.0 9.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIW73559.1 - 7.1e-05 22.0 0.1 0.00017 20.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIW73559.1 - 0.00036 20.6 0.0 0.00086 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EIW73559.1 - 0.00051 19.2 0.0 0.61 9.0 0.0 2.3 1 1 1 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EIW73559.1 - 0.00098 18.6 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW73559.1 - 0.0017 18.3 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EIW73559.1 - 0.025 13.8 0.2 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EIW73559.1 - 0.025 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EIW73559.1 - 0.026 14.8 0.1 0.048 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.7 EIW73559.1 - 0.061 13.0 0.4 0.16 11.6 0.3 1.7 1 0 0 1 1 1 0 CDR ABC transporter AAA_17 PF13207.1 EIW73559.1 - 0.15 12.8 0.0 0.3 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EIW73559.1 - 0.16 11.0 0.2 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EIW73559.1 - 0.17 11.8 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EIW73559.1 - 0.18 11.7 0.0 0.63 9.9 0.0 2.0 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Fes1 PF08609.5 EIW73560.1 - 4.4e-11 43.1 3.4 2.3e-05 24.7 0.7 2.6 2 0 0 2 2 2 2 Nucleotide exchange factor Fes1 Arm PF00514.18 EIW73560.1 - 0.0033 17.2 0.6 0.64 9.9 0.2 3.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIW73560.1 - 0.034 14.4 0.0 0.09 13.0 0.0 1.8 1 0 0 1 1 1 0 HEAT repeats HEAT_EZ PF13513.1 EIW73560.1 - 0.037 14.5 0.4 0.35 11.4 0.0 2.5 1 1 1 2 2 2 0 HEAT-like repeat HAD PF12710.2 EIW73562.1 - 4.7e-26 92.1 0.0 7.9e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EIW73562.1 - 3.6e-25 88.3 0.0 8.1e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EIW73562.1 - 1.2e-22 81.3 0.0 1.1e-21 78.2 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EIW73562.1 - 3.2e-21 75.3 0.0 6.9e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_C PF00689.16 EIW73562.1 - 8.8e-05 22.1 5.7 8.8e-05 22.1 4.0 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EIW73562.1 - 0.00041 20.2 0.0 0.00094 19.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIW73562.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIW73562.1 - 0.045 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus LSM PF01423.17 EIW73565.1 - 1.3e-19 69.4 0.1 1.5e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIW73565.1 - 0.039 13.8 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LRR_6 PF13516.1 EIW73566.1 - 9e-11 40.6 12.0 0.056 13.5 0.1 7.8 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 EIW73566.1 - 2e-07 30.4 23.0 0.00027 20.4 0.6 6.5 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIW73566.1 - 2.5e-06 26.7 5.4 2.7 8.3 0.0 7.3 7 2 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.1 EIW73566.1 - 0.00031 20.4 16.1 0.043 13.5 0.7 5.3 2 2 4 6 6 6 4 Leucine rich repeat Prothymosin PF03247.9 EIW73566.1 - 0.019 15.1 13.5 0.034 14.2 9.3 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family LRR_2 PF07723.8 EIW73566.1 - 0.029 14.8 0.4 1.9 9.1 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_7 PF13504.1 EIW73566.1 - 0.04 14.0 5.4 61 4.4 0.0 5.7 6 0 0 6 6 6 0 Leucine rich repeat CENP-B_dimeris PF09026.5 EIW73566.1 - 3.8 7.8 15.7 7.1 6.9 10.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EIW73566.1 - 9.6 5.7 10.6 20 4.6 7.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Tyr-DNA_phospho PF06087.7 EIW73567.1 - 2.9e-51 174.5 0.0 4.1e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 EIW73567.1 - 4.9e-07 28.7 7.2 0.0079 15.6 0.2 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif PLDc_2 PF13091.1 EIW73567.1 - 0.0012 18.5 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain SIS PF01380.17 EIW73568.1 - 2.4e-58 195.4 0.0 5.3e-29 100.4 0.0 2.7 3 0 0 3 3 3 2 SIS domain GATase_2 PF00310.16 EIW73568.1 - 9.7e-24 83.7 0.1 2.6e-16 59.2 0.0 2.7 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIW73568.1 - 2.6e-18 66.2 0.0 5.4e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EIW73568.1 - 3.7e-14 52.5 0.0 7.4e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EIW73568.1 - 2.6e-07 29.6 0.0 5e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II COMPASS-Shg1 PF05205.7 EIW73568.1 - 0.032 14.5 0.1 0.14 12.4 0.0 2.1 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 CBFB_NFYA PF02045.10 EIW73569.1 - 3.5e-29 101.1 6.1 6.6e-29 100.2 4.3 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DNA_pol_phi PF04931.8 EIW73569.1 - 7.7 4.1 8.2 9.1 3.9 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi OSCP PF00213.13 EIW73570.1 - 6.9e-39 133.4 0.4 8.6e-39 133.1 0.3 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit KaiB PF07689.7 EIW73570.1 - 0.016 14.6 0.0 0.062 12.7 0.0 1.9 1 1 1 2 2 2 0 KaiB domain Val_tRNA-synt_C PF10458.4 EIW73570.1 - 0.61 10.2 3.5 0.84 9.7 0.2 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DSPc PF00782.15 EIW73571.1 - 4.2e-21 74.9 0.0 2e-18 66.2 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW73571.1 - 0.00024 20.5 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EIW73571.1 - 0.15 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Prenyltrans PF00432.16 EIW73572.1 - 5.3e-43 144.2 11.6 2.7e-11 42.8 0.0 6.4 6 1 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIW73572.1 - 5e-27 94.5 0.0 2.2e-09 37.7 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Proteasome PF00227.21 EIW73573.1 - 2.2e-59 199.9 0.0 3.2e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW73573.1 - 4.1e-15 54.7 0.2 1.4e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature IFRD PF05004.8 EIW73573.1 - 0.06 12.4 0.2 0.089 11.8 0.2 1.2 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Hint PF01079.15 EIW73573.1 - 0.07 12.3 0.3 0.31 10.1 0.0 1.9 2 0 0 2 2 2 0 Hint module DUF1631 PF07793.6 EIW73573.1 - 0.13 10.4 0.5 0.17 10.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF1212 PF06738.7 EIW73575.1 - 7e-34 116.9 1.0 7e-34 116.9 0.7 2.8 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIW73575.1 - 1.4e-17 63.8 11.6 1.4e-17 63.8 8.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) EcsB PF05975.7 EIW73575.1 - 0.0028 16.2 0.4 0.0028 16.2 0.3 1.9 2 1 0 2 2 2 1 Bacterial ABC transporter protein EcsB AAA PF00004.24 EIW73576.1 - 1.3e-54 183.9 0.0 1.9e-43 147.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EIW73576.1 - 1.2e-24 86.1 0.4 3.1e-24 84.7 0.1 1.9 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EIW73576.1 - 2e-15 57.2 2.5 2.1e-06 27.8 0.0 5.0 3 2 2 5 5 5 2 AAA ATPase domain NACHT PF05729.7 EIW73576.1 - 2.8e-08 33.5 1.5 0.00021 20.9 0.1 4.3 3 1 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EIW73576.1 - 5.4e-08 33.6 0.0 0.0053 17.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW73576.1 - 2.7e-07 30.7 1.4 0.06 13.4 0.2 4.1 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EIW73576.1 - 3.8e-07 30.0 0.0 0.022 14.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIW73576.1 - 2.8e-06 27.1 0.2 0.042 13.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EIW73576.1 - 5.9e-06 25.4 0.0 0.0027 16.8 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIW73576.1 - 1.3e-05 24.8 0.0 0.13 12.0 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain TIP49 PF06068.8 EIW73576.1 - 1.3e-05 24.1 0.6 0.04 12.6 0.0 3.1 3 0 0 3 3 3 2 TIP49 C-terminus AAA_25 PF13481.1 EIW73576.1 - 1.6e-05 24.3 3.7 1.1 8.6 0.0 4.2 2 2 1 4 4 4 2 AAA domain AAA_18 PF13238.1 EIW73576.1 - 6.4e-05 23.2 0.0 0.61 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EIW73576.1 - 0.00019 21.4 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW73576.1 - 0.00031 20.6 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW73576.1 - 0.00034 20.7 0.0 0.79 9.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 EIW73576.1 - 0.00044 20.0 0.0 0.33 10.6 0.0 3.2 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 EIW73576.1 - 0.0011 18.4 0.1 0.57 9.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.10 EIW73576.1 - 0.0012 18.5 0.3 0.078 12.6 0.1 2.5 2 0 0 2 2 2 1 NTPase ABC_tran PF00005.22 EIW73576.1 - 0.0015 18.8 0.0 0.49 10.6 0.0 3.1 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.1 EIW73576.1 - 0.0019 17.8 0.1 2.1 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EIW73576.1 - 0.0026 17.8 0.0 2.4 8.2 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain DUF815 PF05673.8 EIW73576.1 - 0.0044 15.9 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 EIW73576.1 - 0.0081 15.0 0.0 1.3 7.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Bac_DnaA PF00308.13 EIW73576.1 - 0.01 15.4 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Zeta_toxin PF06414.7 EIW73576.1 - 0.012 14.7 0.0 0.63 9.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_3 PF07726.6 EIW73576.1 - 0.015 14.8 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIW73576.1 - 0.017 15.0 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EIW73576.1 - 0.023 13.8 0.1 0.58 9.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 EIW73576.1 - 0.03 13.8 0.0 0.37 10.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EIW73576.1 - 0.033 13.8 0.1 7.2 6.2 0.0 2.7 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EIW73576.1 - 0.035 13.0 0.0 0.47 9.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EIW73576.1 - 0.065 12.7 0.1 1.3 8.5 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EIW73576.1 - 0.068 12.1 0.0 2.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Miro PF08477.8 EIW73576.1 - 0.07 13.6 0.0 0.57 10.6 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein KaiC PF06745.8 EIW73576.1 - 0.08 12.0 0.4 7.4 5.6 0.0 3.0 3 1 1 4 4 4 0 KaiC cobW PF02492.14 EIW73576.1 - 0.081 12.3 0.1 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin2 PF13189.1 EIW73576.1 - 0.095 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family MobB PF03205.9 EIW73576.1 - 0.12 12.1 0.1 0.63 9.7 0.0 2.3 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B DAP3 PF10236.4 EIW73576.1 - 0.12 11.2 0.4 3 6.6 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Rad17 PF03215.10 EIW73576.1 - 0.26 9.9 0.0 1 7.9 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 EIW73576.1 - 0.28 10.0 0.0 6.4 5.5 0.0 2.6 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 Aa_trans PF01490.13 EIW73577.1 - 8.5e-89 297.8 33.5 1e-88 297.6 23.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein WLM PF08325.5 EIW73578.1 - 5.7e-49 166.5 0.0 9.2e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EIW73578.1 - 5.5e-07 28.5 4.5 5.5e-07 28.5 3.2 3.1 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 EIW73578.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 DZR PF12773.2 EIW73578.1 - 0.18 11.6 9.1 0.33 10.8 6.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon ABC_tran PF00005.22 EIW73579.1 - 1.4e-44 151.7 0.0 6.3e-22 78.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW73579.1 - 1.1e-13 51.8 10.4 3.4e-05 23.9 0.7 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EIW73579.1 - 4.4e-13 48.9 1.2 0.00046 19.4 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIW73579.1 - 1.5e-09 37.2 0.1 0.0023 17.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT_2 PF13646.1 EIW73579.1 - 2.1e-09 37.5 3.9 0.0029 17.8 0.0 3.8 4 0 0 4 4 3 2 HEAT repeats HEAT PF02985.17 EIW73579.1 - 9e-09 34.6 2.6 0.0045 16.9 0.0 4.4 4 0 0 4 4 3 2 HEAT repeat MMR_HSR1 PF01926.18 EIW73579.1 - 4.4e-07 29.8 0.0 0.01 15.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.1 EIW73579.1 - 7.5e-07 28.9 0.0 0.014 15.3 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EIW73579.1 - 3e-06 26.9 0.1 0.086 12.2 0.0 2.8 3 0 0 3 3 2 2 AAA-like domain AAA_23 PF13476.1 EIW73579.1 - 3.4e-06 27.5 1.7 0.086 13.1 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EIW73579.1 - 4.5e-06 25.9 1.2 0.05 12.6 0.0 3.5 3 1 1 4 4 3 1 AAA ATPase domain DUF258 PF03193.11 EIW73579.1 - 4.5e-06 25.9 0.0 0.065 12.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 EIW73579.1 - 7.3e-06 25.9 1.3 0.005 16.6 0.0 3.0 3 0 0 3 3 2 1 Domain of unknown function DUF87 Miro PF08477.8 EIW73579.1 - 2e-05 25.0 0.0 0.027 14.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 EIW73579.1 - 3.2e-05 24.7 0.2 0.034 14.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIW73579.1 - 4.2e-05 23.5 0.0 0.05 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW73579.1 - 5.9e-05 23.1 0.1 0.16 11.9 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain HEAT_EZ PF13513.1 EIW73579.1 - 6.2e-05 23.3 9.6 0.036 14.5 0.2 5.8 4 2 2 6 6 5 1 HEAT-like repeat NACHT PF05729.7 EIW73579.1 - 0.00011 21.8 0.1 0.67 9.5 0.0 2.7 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 EIW73579.1 - 0.00012 21.8 0.0 0.14 11.8 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Chromo PF00385.19 EIW73579.1 - 0.00013 21.5 0.0 0.00032 20.2 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.1 EIW73579.1 - 0.00018 21.6 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EIW73579.1 - 0.00019 20.3 0.2 0.24 10.1 0.0 3.1 3 0 0 3 3 3 1 ArgK protein Adaptin_N PF01602.15 EIW73579.1 - 0.00023 19.6 0.5 0.00043 18.7 0.4 1.5 1 0 0 1 1 1 1 Adaptin N terminal region Arch_ATPase PF01637.13 EIW73579.1 - 0.00025 20.8 0.0 0.22 11.1 0.0 2.9 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 EIW73579.1 - 0.00041 20.4 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 EIW73579.1 - 0.0005 20.2 0.0 2.7 8.1 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIW73579.1 - 0.00064 19.1 0.0 0.68 9.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_13 PF13166.1 EIW73579.1 - 0.001 17.6 0.0 0.88 7.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EIW73579.1 - 0.0012 18.4 1.8 2.6 7.4 0.0 3.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EIW73579.1 - 0.0014 18.5 0.8 3.2 7.6 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EIW73579.1 - 0.0014 18.9 0.1 0.098 12.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 EIW73579.1 - 0.0021 17.9 0.0 2.9 7.7 0.0 2.6 2 0 0 2 2 2 2 Dynamin family AAA_5 PF07728.9 EIW73579.1 - 0.0075 16.0 0.3 6.1 6.5 0.1 4.2 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EIW73579.1 - 0.0095 15.6 0.1 6 6.6 0.0 3.4 3 0 0 3 3 3 0 Part of AAA domain AAA_30 PF13604.1 EIW73579.1 - 0.011 15.3 0.1 3.3 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIW73579.1 - 0.013 14.3 0.3 1.2 7.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.1 EIW73579.1 - 0.015 15.1 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EIW73579.1 - 0.021 13.7 0.2 6 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 EIW73579.1 - 0.037 13.5 0.0 6.6 6.2 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.1 EIW73579.1 - 0.051 13.6 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 1 0 Sigma-54 interaction domain Ras PF00071.17 EIW73579.1 - 0.062 12.6 0.1 5.9 6.2 0.0 3.1 3 0 0 3 3 3 0 Ras family Arm PF00514.18 EIW73579.1 - 0.062 13.1 0.1 0.53 10.1 0.0 2.8 2 0 0 2 2 1 0 Armadillo/beta-catenin-like repeat ATP-synt_ab PF00006.20 EIW73579.1 - 0.073 12.5 0.0 1.5 8.2 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.15 EIW73579.1 - 0.17 10.5 0.1 3.3 6.2 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit cobW PF02492.14 EIW73579.1 - 0.21 10.9 2.7 15 5.0 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Fmp27_WPPW PF10359.4 EIW73580.1 - 1.4e-64 218.2 0.2 2e-64 217.7 0.1 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 EIW73580.1 - 4.8e-60 203.7 0.8 6.8e-44 150.4 0.0 3.0 2 1 1 3 3 3 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 EIW73580.1 - 1.8e-45 154.6 0.0 4.2e-45 153.4 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EIW73580.1 - 7.4e-27 94.0 0.0 2e-26 92.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EIW73580.1 - 0.00016 22.0 0.0 0.00047 20.5 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain adh_short PF00106.20 EIW73581.1 - 6.6e-25 87.9 0.0 8.4e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW73581.1 - 8.4e-20 71.5 0.0 1.1e-19 71.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW73581.1 - 3.7e-06 26.7 0.0 5.3e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_7 PF13241.1 EIW73581.1 - 0.068 13.4 0.0 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding PEMT PF04191.8 EIW73582.1 - 4.3e-29 100.7 3.2 4.3e-29 100.7 2.2 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase SUV3_C PF12513.3 EIW73583.1 - 1.7e-13 49.7 0.1 3.4e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EIW73583.1 - 1.5e-11 44.0 0.0 3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PH PF00169.24 EIW73584.1 - 2.8e-32 110.9 1.7 8.3e-18 64.5 0.3 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EIW73584.1 - 5.8e-12 45.8 13.6 4.6e-08 33.3 2.6 4.2 3 2 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 EIW73584.1 - 2.5e-11 43.3 2.1 5.6e-06 26.1 0.3 3.4 3 0 0 3 3 3 3 PH domain PH_8 PF15409.1 EIW73584.1 - 5e-07 29.7 2.5 3.9e-05 23.6 0.6 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.1 EIW73584.1 - 3.6e-05 23.8 3.7 0.0015 18.7 0.6 3.6 2 2 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.1 EIW73584.1 - 0.00017 21.1 5.8 0.0086 15.6 0.1 3.1 3 0 0 3 3 3 2 Pleckstrin homology domain PH_6 PF15406.1 EIW73584.1 - 0.06 13.4 0.1 0.23 11.5 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain SE PF08491.5 EIW73585.1 - 8.5e-88 293.7 0.0 1.2e-87 293.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EIW73585.1 - 1.4e-06 27.5 0.3 7.1e-06 25.1 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW73585.1 - 4.5e-05 22.6 0.8 0.0011 18.0 0.6 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW73585.1 - 8.7e-05 22.4 0.6 0.00044 20.2 0.5 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW73585.1 - 0.00036 19.7 0.0 0.0092 15.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EIW73585.1 - 0.00055 18.9 0.9 0.0039 16.1 0.7 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EIW73585.1 - 0.0028 16.6 0.2 0.19 10.6 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIW73585.1 - 0.0041 16.0 1.1 0.017 13.9 0.8 1.8 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 EIW73585.1 - 0.007 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EIW73585.1 - 0.033 14.0 0.1 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIW73585.1 - 0.042 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EIW73585.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EIW73585.1 - 0.13 11.6 0.2 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EIW73585.1 - 0.19 10.1 0.1 0.27 9.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 EIW73585.1 - 0.24 10.4 0.7 0.34 9.9 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GTP_EFTU PF00009.22 EIW73586.1 - 1.9e-61 206.7 0.0 2.8e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIW73586.1 - 8.9e-38 128.5 0.0 2.7e-37 126.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EIW73586.1 - 2.5e-19 68.9 0.0 5.7e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EIW73586.1 - 1.6e-13 50.3 0.0 3.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EIW73586.1 - 1.8e-10 40.7 0.0 5.3e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW73586.1 - 3.7e-05 23.6 0.1 8.1e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EIW73586.1 - 0.041 13.3 0.2 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation YL1 PF05764.8 EIW73587.1 - 8.6e-24 84.4 30.4 8.6e-24 84.4 21.0 1.7 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EIW73587.1 - 3.8e-10 39.1 0.5 6.7e-10 38.3 0.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain V_ATPase_I PF01496.14 EIW73588.1 - 7.8e-269 893.6 0.0 8.9e-269 893.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Cortex-I_coil PF09304.5 EIW73588.1 - 0.41 10.7 3.1 2.2 8.3 0.3 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil PIGA PF08288.7 EIW73589.1 - 6.4e-38 129.0 0.1 6.4e-38 129.0 0.1 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Acyltransferase PF01553.16 EIW73589.1 - 2.7e-28 98.0 0.0 7e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase Glycos_transf_1 PF00534.15 EIW73589.1 - 1e-24 86.8 0.0 1.6e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EIW73589.1 - 1.1e-19 70.8 0.1 1.8e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EIW73589.1 - 3.5e-17 63.0 0.4 6.7e-17 62.0 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EIW73589.1 - 7e-11 42.4 0.0 1.8e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EIW73589.1 - 1.4e-05 25.2 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EIW73589.1 - 0.00021 21.1 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_28 PF03033.15 EIW73589.1 - 0.032 13.9 0.1 0.088 12.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain DUF2317 PF10079.4 EIW73590.1 - 1.9 6.9 10.5 0.06 11.9 1.7 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2317) UDPGT PF00201.13 EIW73591.1 - 1.4e-17 63.4 0.0 2e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EIW73591.1 - 0.079 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Allantoicase PF03561.10 EIW73593.1 - 4.9e-78 259.8 0.0 7.9e-40 135.7 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 EIW73593.1 - 6.1e-53 178.5 0.0 4.4e-25 87.9 0.0 2.9 2 1 0 2 2 2 2 Ureidoglycolate hydrolase AA_permease PF00324.16 EIW73594.1 - 8.8e-121 403.5 33.3 1.1e-120 403.2 23.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW73594.1 - 3.4e-34 118.1 38.7 4.2e-34 117.8 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease IlvB_leader PF08049.6 EIW73594.1 - 0.26 11.0 1.0 0.73 9.6 0.7 1.8 1 0 0 1 1 1 0 IlvB leader peptide GPI-anchored PF10342.4 EIW73595.1 - 2.2e-16 60.1 6.0 2.2e-16 60.1 4.2 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 EIW73596.1 - 5.1e-06 26.8 0.0 1.4e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family InvH PF04741.7 EIW73597.1 - 0.0087 15.9 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 1 InvH outer membrane lipoprotein PseudoU_synth_2 PF00849.17 EIW73598.1 - 6.9e-29 100.7 0.0 1.1e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase rve PF00665.21 EIW73601.1 - 2.7e-18 66.2 0.0 6.3e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EIW73601.1 - 1.9e-09 37.0 0.5 3.7e-09 36.1 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EIW73601.1 - 0.011 15.1 0.1 0.27 10.6 0.0 2.6 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger zf-CCHC PF00098.18 EIW73602.1 - 0.0013 18.5 1.8 0.002 17.9 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EIW73602.1 - 0.015 14.8 0.1 0.029 13.8 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 EIW73602.1 - 0.069 13.0 3.5 0.13 12.1 2.4 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G BRF1 PF07741.8 EIW73602.1 - 0.083 13.1 8.8 0.047 13.9 3.9 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain GBP_C PF02841.9 EIW73602.1 - 9.9 5.2 9.9 3.3 6.8 3.7 1.9 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DUF2587 PF10759.4 EIW73603.1 - 0.04 13.2 0.1 0.1 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Nop14 PF04147.7 EIW73603.1 - 2.4 5.9 4.2 3.7 5.3 2.9 1.2 1 0 0 1 1 1 0 Nop14-like family Nop10p PF04135.7 EIW73605.1 - 1.7e-20 72.5 0.1 2e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Galactosyl_T PF01762.16 EIW73606.1 - 1.7e-08 34.3 0.1 0.00077 19.1 0.1 2.3 1 1 1 2 2 2 2 Galactosyltransferase TBCA PF02970.11 EIW73607.1 - 4e-16 58.8 1.2 5.1e-16 58.5 0.8 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A TMV_coat PF00721.16 EIW73607.1 - 0.03 14.2 0.1 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 Virus coat protein (TMV like) MARVEL PF01284.18 EIW73608.1 - 4.2e-13 49.3 18.6 5.5e-13 48.9 12.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4079 PF13301.1 EIW73608.1 - 0.55 10.2 8.4 6 6.8 5.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF2975 PF11188.3 EIW73608.1 - 7.6 6.2 13.7 3.9 7.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Sec7 PF01369.15 EIW73609.1 - 1.9e-65 220.1 0.6 1.9e-65 220.1 0.4 2.5 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 EIW73609.1 - 1.4e-54 184.0 12.9 1.5e-54 183.9 5.3 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EIW73609.1 - 8.6e-32 108.5 8.8 5e-29 99.6 0.3 5.3 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) RRM_1 PF00076.17 EIW73610.1 - 4.2e-06 26.2 0.0 5.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW73610.1 - 0.0074 16.2 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW73610.1 - 0.0082 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIW73610.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Limkain b1 DUF1445 PF07286.7 EIW73611.1 - 0.12 12.0 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) DUF2962 PF11176.3 EIW73612.1 - 1.1e-30 106.2 0.0 1.3e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) TRAPPC9-Trs120 PF08626.6 EIW73613.1 - 3.1e-54 183.8 0.0 3.5e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit AAA_23 PF13476.1 EIW73614.1 - 4.5e-15 56.5 0.0 5.2e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EIW73614.1 - 3.5e-14 52.5 0.0 3.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIW73614.1 - 0.00099 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EIW73614.1 - 0.0097 16.1 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EIW73614.1 - 0.01 15.8 0.1 0.014 15.3 0.1 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW73614.1 - 0.01 16.1 0.4 0.014 15.6 0.3 1.6 1 1 0 1 1 1 0 ABC transporter AAA_13 PF13166.1 EIW73614.1 - 0.014 13.9 0.0 0.024 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EIW73614.1 - 0.077 12.0 0.0 0.084 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.11 EIW73614.1 - 0.092 11.9 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.12 EIW73614.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein SAGA-Tad1 PF12767.2 EIW73615.1 - 2.3e-25 89.7 0.3 1.4e-24 87.1 0.0 2.2 2 1 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Ribosomal_S28e PF01200.13 EIW73616.1 - 7.7e-30 102.4 0.5 9e-30 102.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e AlaDh_PNT_N PF05222.10 EIW73617.1 - 4.9e-25 88.1 0.0 8.4e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EIW73617.1 - 7.6e-14 51.6 0.1 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain tRNA-synt_2 PF00152.15 EIW73618.1 - 1.7e-78 263.7 0.0 2.7e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIW73618.1 - 0.00021 21.0 0.1 0.00046 19.9 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Peptidase_M64 PF09471.5 EIW73619.1 - 3.7e-20 72.6 0.0 6.2e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 IgA Peptidase M64 MFS_1 PF07690.11 EIW73620.1 - 5e-48 163.5 49.4 8.6e-48 162.8 34.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW73620.1 - 7.2e-23 80.6 28.8 9.1e-23 80.2 20.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW73620.1 - 2.5e-16 59.3 36.6 5.1e-16 58.2 12.0 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.3 EIW73620.1 - 6.1e-06 24.9 10.9 6.1e-06 24.9 7.5 2.3 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_2 PF13347.1 EIW73620.1 - 5.7e-05 21.6 5.1 5.7e-05 21.6 3.5 2.9 2 2 0 2 2 2 2 MFS/sugar transport protein Ndc1_Nup PF09531.5 EIW73621.1 - 5.7e-45 153.8 6.4 7.1e-45 153.5 4.4 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup GHMP_kinases_N PF00288.21 EIW73622.1 - 1.9e-07 31.0 3.9 8e-07 29.0 2.7 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain NAPRTase PF04095.11 EIW73623.1 - 1.6e-46 158.5 0.0 2.3e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family PPR_2 PF13041.1 EIW73624.1 - 6.6e-07 29.2 2.0 0.26 11.3 0.0 5.8 6 0 0 6 6 6 2 PPR repeat family PPR_3 PF13812.1 EIW73624.1 - 0.00096 19.2 1.1 1.5 9.2 0.0 5.3 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EIW73624.1 - 0.0053 16.6 11.2 6 7.0 0.0 7.1 8 0 0 8 8 8 1 PPR repeat PPR_1 PF12854.2 EIW73624.1 - 0.0095 15.3 0.4 12 5.5 0.0 4.2 5 0 0 5 5 5 1 PPR repeat Pkinase PF00069.20 EIW73625.1 - 4.7e-67 225.8 0.0 7.5e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73625.1 - 6.3e-51 172.9 0.0 1.9e-50 171.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW73625.1 - 0.00012 21.1 0.0 0.00022 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like zf-C3HC4_2 PF13923.1 EIW73626.1 - 6e-08 32.5 22.6 8e-05 22.5 1.2 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW73626.1 - 1.7e-06 27.6 21.3 8.5e-05 22.1 4.1 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW73626.1 - 4.9e-05 23.0 16.8 0.0023 17.7 2.5 3.3 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 EIW73626.1 - 0.011 15.3 7.9 0.011 15.3 5.4 3.7 3 1 0 3 3 3 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW73626.1 - 0.016 14.8 23.0 0.17 11.5 1.3 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW73626.1 - 0.25 11.0 7.3 1.4 8.7 1.6 3.2 3 0 0 3 3 3 0 RING-type zinc-finger Rtf2 PF04641.7 EIW73626.1 - 1.3 8.1 11.1 3.5 6.7 0.0 3.2 3 1 1 4 4 4 0 Rtf2 RING-finger ATP-synt_B PF00430.13 EIW73626.1 - 7.8 6.3 9.0 0.56 10.0 0.8 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Sugar_tr PF00083.19 EIW73627.1 - 5.9e-65 219.6 2.9 7.6e-65 219.2 2.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW73627.1 - 6.8e-15 54.6 25.3 9.8e-15 54.1 17.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.20 EIW73628.1 - 2.8e-31 108.6 0.0 4.9e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73628.1 - 1.3e-05 24.4 0.0 2.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW73628.1 - 1.6e-05 24.8 0.0 5.1e-05 23.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW73628.1 - 0.031 13.8 0.0 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Raptor_N PF14538.1 EIW73629.1 - 3.1e-61 205.7 0.1 8.1e-61 204.3 0.0 1.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EIW73629.1 - 8.9e-08 31.7 6.4 0.013 15.3 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT PF02985.17 EIW73629.1 - 0.00044 20.0 0.9 0.049 13.7 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EIW73629.1 - 0.03 14.7 0.1 0.36 11.3 0.0 3.1 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.1 EIW73629.1 - 0.075 13.3 0.9 0.4 10.9 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats PCI PF01399.22 EIW73630.1 - 8.6e-21 74.2 1.4 2.8e-20 72.5 0.1 2.5 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EIW73630.1 - 3.8e-11 42.9 0.6 8.2e-11 41.8 0.1 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EIW73630.1 - 0.022 14.6 0.7 0.2 11.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat APC8 PF04049.8 EIW73630.1 - 0.023 14.4 0.2 0.053 13.2 0.1 1.6 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 TPR_16 PF13432.1 EIW73630.1 - 0.1 13.2 2.2 4.5 8.0 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW73630.1 - 0.24 11.9 4.0 11 6.7 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW73630.1 - 0.27 11.9 2.3 8.5 7.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIW73630.1 - 0.54 10.2 3.7 2.7 8.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Con-6 PF10346.4 EIW73631.1 - 1.6e-22 78.6 5.8 3.4e-11 42.3 0.5 2.3 2 0 0 2 2 2 2 Conidiation protein 6 Ceramidase PF05875.7 EIW73632.1 - 4.6e-75 252.1 5.1 5.9e-75 251.7 3.5 1.0 1 0 0 1 1 1 1 Ceramidase Sugar_tr PF00083.19 EIW73633.1 - 1.7e-117 392.7 34.2 2e-117 392.5 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW73633.1 - 2e-13 49.8 60.0 8e-09 34.6 19.1 2.7 1 1 1 3 3 3 2 Major Facilitator Superfamily RRM_1 PF00076.17 EIW73634.1 - 6.2e-16 57.7 0.0 8.6e-16 57.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW73634.1 - 6.1e-15 54.9 0.0 8.7e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW73634.1 - 9.9e-08 31.7 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.22 EIW73637.1 - 6.7e-43 146.3 0.0 1e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIW73637.1 - 4e-28 97.3 0.0 9e-28 96.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EIW73637.1 - 2.8e-21 75.1 0.0 1e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIW73637.1 - 1.6e-09 37.7 0.1 4.2e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EIW73637.1 - 1.2e-06 28.2 0.0 2.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EIW73637.1 - 1.3e-05 25.1 0.1 2.3e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW73637.1 - 0.00024 21.5 0.1 0.00059 20.3 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EIW73637.1 - 0.025 13.8 0.1 0.078 12.1 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EIW73637.1 - 0.14 11.9 0.6 26 4.6 0.0 2.6 1 1 0 2 2 2 0 Dynamin family Ipi1_N PF12333.3 EIW73638.1 - 1e-11 44.6 0.3 2e-10 40.5 0.0 3.0 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 EIW73638.1 - 0.0084 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Serglycin PF04360.7 EIW73639.1 - 0.0044 16.7 1.4 0.0081 15.9 1.0 1.5 1 0 0 1 1 1 1 Serglycin P12 PF12669.2 EIW73639.1 - 0.0058 16.8 1.5 0.0062 16.7 0.1 1.6 2 0 0 2 2 2 1 Virus attachment protein p12 family TGF_beta_GS PF08515.7 EIW73639.1 - 1.9 7.8 11.8 0.8 9.0 1.0 2.9 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif DUF2593 PF10767.4 EIW73640.1 - 0.11 12.1 0.3 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) CPSF100_C PF13299.1 EIW73641.1 - 1.1e-30 106.9 0.4 3.8e-30 105.2 0.0 2.1 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EIW73641.1 - 2.6e-14 53.2 0.0 7e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Sec7 PF01369.15 EIW73642.1 - 4.8e-25 88.3 0.7 9.2e-25 87.4 0.5 1.4 1 0 0 1 1 1 1 Sec7 domain Ssu72 PF04722.8 EIW73643.1 - 2.7e-65 219.3 0.0 3e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Nup160 PF11715.3 EIW73644.1 - 1.1e-65 221.8 0.1 1.8e-65 221.1 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 CN_hydrolase PF00795.17 EIW73645.1 - 0.00011 21.5 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Sugar_tr PF00083.19 EIW73646.1 - 2.8e-35 121.7 34.0 2.1e-22 79.3 6.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIW73646.1 - 4e-15 55.3 45.3 3.6e-11 42.3 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_11 PF13414.1 EIW73648.1 - 5.4e-47 157.3 24.1 1e-12 47.4 0.2 12.1 9 4 6 15 15 15 12 TPR repeat TPR_1 PF00515.23 EIW73648.1 - 8.4e-43 142.2 16.5 3.9e-07 29.4 0.0 12.0 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_2 PF07719.12 EIW73648.1 - 2e-39 130.3 18.0 0.00018 21.1 0.0 14.4 15 0 0 15 15 14 7 Tetratricopeptide repeat TPR_16 PF13432.1 EIW73648.1 - 2.4e-32 110.8 34.0 1e-10 41.9 0.2 11.2 11 1 3 14 14 12 7 Tetratricopeptide repeat TPR_12 PF13424.1 EIW73648.1 - 2.9e-28 97.6 30.4 5.9e-07 29.3 0.7 12.4 10 3 3 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.1 EIW73648.1 - 3.5e-28 95.2 12.6 6.2e-06 25.6 0.0 12.3 11 2 2 13 13 12 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIW73648.1 - 5.1e-27 91.7 13.2 0.0065 16.5 0.0 13.4 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 EIW73648.1 - 6.2e-25 87.3 28.2 7.5e-07 29.3 0.0 10.5 9 2 1 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIW73648.1 - 1.9e-22 77.7 37.1 0.006 17.1 0.0 15.5 12 4 7 19 19 15 7 Tetratricopeptide repeat TPR_6 PF13174.1 EIW73648.1 - 1.8e-13 49.9 10.6 0.00092 19.5 0.0 12.2 15 0 0 15 15 12 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW73648.1 - 6.5e-13 47.4 16.8 0.00029 20.3 0.0 10.8 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIW73648.1 - 1.1e-12 47.6 18.2 0.00019 21.1 0.1 8.9 9 1 1 10 10 10 3 Tetratricopeptide repeat Apc3 PF12895.2 EIW73648.1 - 4.1e-11 42.8 14.0 1.8e-05 24.7 0.7 7.5 6 2 2 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EIW73648.1 - 1.6e-07 30.6 12.5 0.33 9.9 0.0 6.7 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_20 PF14561.1 EIW73648.1 - 2.9e-07 30.5 10.0 0.28 11.3 0.0 7.2 7 1 1 8 8 7 2 Tetratricopeptide repeat RPN7 PF10602.4 EIW73648.1 - 0.0057 16.0 0.5 20 4.5 0.0 5.0 4 1 2 6 6 6 0 26S proteasome subunit RPN7 ChAPs PF09295.5 EIW73648.1 - 0.05 12.3 0.4 0.32 9.7 0.0 2.5 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) NatB_MDM20 PF09797.4 EIW73648.1 - 0.058 12.1 4.1 0.69 8.5 0.0 3.0 3 0 0 3 3 3 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF3856 PF12968.2 EIW73648.1 - 0.085 12.6 3.0 1.4 8.7 0.0 4.0 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) SPO22 PF08631.5 EIW73648.1 - 0.5 9.4 3.8 2.5 7.1 0.0 3.8 3 1 1 4 4 4 0 Meiosis protein SPO22/ZIP4 like Fis1_TPR_C PF14853.1 EIW73648.1 - 0.53 10.2 7.2 9.5 6.1 0.1 5.3 6 1 1 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 EIW73648.1 - 1 9.9 25.9 2.9 8.5 0.4 9.0 10 0 0 10 10 8 0 Tetratricopeptide repeat Pkinase PF00069.20 EIW73649.1 - 4.1e-49 167.0 0.0 3e-46 157.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73649.1 - 6.1e-18 64.8 0.0 1.1e-15 57.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW73649.1 - 0.0004 19.4 0.0 0.0007 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW73649.1 - 0.00043 20.0 2.2 0.00046 19.9 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW73649.1 - 0.00055 19.0 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIW73649.1 - 0.46 9.8 0.0 1.7 7.9 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Complex1_LYR PF05347.10 EIW73650.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Cytochrom_B561 PF03188.11 EIW73651.1 - 2e-06 27.6 3.6 2e-06 27.6 2.5 2.0 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EIW73651.1 - 1.1e-05 25.3 0.2 3.6e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 DOMON domain DUF2427 PF10348.4 EIW73651.1 - 0.045 13.3 3.2 0.051 13.1 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DOMON PF03351.12 EIW73652.1 - 4.8e-08 32.9 0.0 8.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 EIW73652.1 - 2.1e-05 24.3 9.3 5.1e-05 23.1 5.3 2.4 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EIW73652.1 - 0.041 13.4 2.9 0.15 11.6 2.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) adh_short_C2 PF13561.1 EIW73653.1 - 4.5e-32 111.7 0.0 5.7e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW73653.1 - 1.1e-31 109.9 0.1 1.4e-31 109.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW73653.1 - 4.1e-12 46.1 0.0 5.5e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW73653.1 - 9.8e-05 21.8 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.1 EIW73653.1 - 0.0034 17.5 0.0 2.2 8.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain THF_DHG_CYH_C PF02882.14 EIW73653.1 - 0.016 14.2 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 EIW73653.1 - 0.025 13.7 0.1 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EIW73653.1 - 0.049 13.4 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_deac_1 PF01522.16 EIW73655.1 - 4e-25 87.8 0.0 7.5e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Herpes_capsid PF06112.6 EIW73655.1 - 8.9 6.3 10.3 12 5.9 6.3 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Nbl1_Borealin_N PF10444.4 EIW73656.1 - 3.1e-18 64.8 0.2 5.1e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Rep_fac-A_C PF08646.5 EIW73657.1 - 7.5e-50 168.4 2.3 4.6e-47 159.4 0.1 3.2 4 0 0 4 4 4 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EIW73657.1 - 3.4e-25 87.7 0.1 6.7e-25 86.8 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EIW73657.1 - 2.4e-14 52.9 1.8 1.5e-12 47.1 0.1 3.5 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 EIW73657.1 - 0.0053 16.7 0.2 0.021 14.9 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function DUF223 DUF3785 PF12653.2 EIW73657.1 - 0.019 14.8 0.7 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) DUF3999 PF13163.1 EIW73657.1 - 0.031 13.2 0.1 0.07 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3999) zf-Nse PF11789.3 EIW73658.1 - 2.7e-17 62.0 0.1 4.7e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EIW73658.1 - 6e-05 22.6 0.1 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger OTU PF02338.14 EIW73658.1 - 0.012 16.2 0.0 0.027 15.0 0.0 1.7 1 1 0 1 1 1 0 OTU-like cysteine protease DUF3829 PF12889.2 EIW73658.1 - 0.019 14.1 0.2 0.049 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Snapin_Pallidin PF14712.1 EIW73658.1 - 0.031 14.5 0.4 0.031 14.5 0.3 2.1 2 1 0 2 2 2 0 Snapin/Pallidin APG6 PF04111.7 EIW73658.1 - 8 5.4 9.1 0.46 9.4 1.5 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2404 PF10296.4 EIW73660.1 - 7.8e-27 93.2 0.0 1.5e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Abhydrolase_5 PF12695.2 EIW73661.1 - 1.8e-18 66.6 0.0 2.8e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW73661.1 - 3.8e-17 62.9 0.1 1e-15 58.2 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW73661.1 - 3.4e-09 36.6 0.0 2.7e-08 33.6 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW73661.1 - 1.5e-06 27.5 0.0 4.9e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.7 EIW73661.1 - 8.1e-05 21.3 0.0 0.00013 20.6 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 AXE1 PF05448.7 EIW73661.1 - 9.7e-05 21.0 0.0 0.00024 19.7 0.0 1.6 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EIW73661.1 - 0.00021 21.0 0.0 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EIW73661.1 - 0.006 16.0 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 EIW73661.1 - 0.0091 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EIW73661.1 - 0.085 12.2 0.0 0.43 9.9 0.0 2.0 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Glycos_transf_N PF04413.11 EIW73662.1 - 0.037 13.1 0.0 0.081 12.0 0.0 1.5 1 1 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) CWC25 PF12542.3 EIW73663.1 - 1.4e-21 76.7 0.0 1.4e-21 76.7 0.0 4.1 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EIW73663.1 - 6e-12 45.3 10.5 6e-12 45.3 7.3 4.7 3 2 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR SPT16 PF08644.6 EIW73663.1 - 2.2 8.1 12.5 0.44 10.3 0.1 3.4 3 1 1 4 4 4 0 FACT complex subunit (SPT16/CDC68) DUF59 PF01883.14 EIW73664.1 - 4.5e-12 45.7 0.1 1.2e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF59 adh_short PF00106.20 EIW73665.1 - 3.7e-23 82.2 0.8 4.8e-23 81.8 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW73665.1 - 9.5e-11 41.9 0.0 1.3e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW73665.1 - 2.6e-08 33.7 0.2 3.7e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EIW73665.1 - 0.0026 17.4 0.8 0.0047 16.5 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UPF0731 PF14982.1 EIW73665.1 - 0.038 13.9 0.6 0.08 12.8 0.1 1.7 2 0 0 2 2 2 0 UPF0731 family UDPG_MGDP_dh_N PF03721.9 EIW73665.1 - 0.085 12.2 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4598 PF15370.1 EIW73666.1 - 0.056 13.7 0.3 0.056 13.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) Microtub_assoc PF07989.6 EIW73667.1 - 8.3e-19 67.1 8.9 8.3e-19 67.1 6.2 8.1 9 1 1 10 10 10 1 Microtubule associated FAD-SLDH PF12318.3 EIW73667.1 - 0.043 13.5 0.2 0.043 13.5 0.1 3.3 3 0 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Reo_sigmaC PF04582.7 EIW73667.1 - 1.4 8.0 26.4 3.1 6.8 2.0 5.4 2 2 3 5 5 5 0 Reovirus sigma C capsid protein RRM_6 PF14259.1 EIW73668.1 - 1.1e-09 38.1 0.0 2.5e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW73668.1 - 4.3e-07 29.4 0.0 1.9e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kelch_3 PF13415.1 EIW73669.1 - 7.3e-31 105.6 12.6 9.3e-10 38.4 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EIW73669.1 - 3.2e-27 93.9 0.2 0.00011 22.0 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EIW73669.1 - 1.9e-25 88.1 0.0 7.8e-06 25.3 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 EIW73669.1 - 5.6e-25 86.8 13.2 3.7e-06 26.6 0.0 7.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EIW73669.1 - 3.6e-22 77.5 0.4 6.2e-06 26.1 0.2 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EIW73669.1 - 1.4e-17 62.7 5.8 0.0039 16.8 0.0 6.7 6 1 0 6 6 6 4 Kelch motif Fib_alpha PF08702.5 EIW73669.1 - 5.9 7.0 40.2 0.88 9.6 3.0 6.2 4 2 0 5 5 5 0 Fibrinogen alpha/beta chain family Prenyltrans PF00432.16 EIW73670.1 - 8.3e-38 127.6 1.7 6.8e-12 44.7 0.1 5.8 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIW73670.1 - 1.4e-29 102.8 3.2 2.9e-17 63.0 0.3 5.0 2 2 2 5 5 5 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIW73670.1 - 2.9e-28 98.0 1.8 2.9e-12 46.5 0.1 5.9 2 2 4 6 6 6 5 Prenyltransferase-like Pec_lyase PF09492.5 EIW73670.1 - 2.2e-05 23.7 0.5 0.69 9.0 0.0 4.3 1 1 2 3 3 3 2 Pectic acid lyase A2M_comp PF07678.9 EIW73670.1 - 0.00052 19.3 2.6 0.0068 15.6 0.2 3.2 2 1 1 3 3 3 1 A-macroglobulin complement component Lactamase_B PF00753.22 EIW73671.1 - 7e-26 91.0 0.5 8.9e-26 90.7 0.4 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EIW73671.1 - 1.5e-05 24.7 0.1 2.4e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EIW73671.1 - 0.0032 17.0 0.3 0.0079 15.7 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain zf-C3HC4_3 PF13920.1 EIW73672.1 - 1.7e-11 43.6 5.3 7.1e-10 38.4 0.7 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW73672.1 - 1.1e-05 25.3 3.0 1.1e-05 25.3 2.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW73672.1 - 0.0023 17.7 7.9 0.024 14.4 5.7 2.1 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EIW73672.1 - 0.0059 16.3 2.5 0.077 12.7 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EIW73672.1 - 1.8 8.1 6.8 0.35 10.4 1.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 EAF PF09816.4 EIW73673.1 - 4.3e-14 52.3 0.0 7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor UQ_con PF00179.21 EIW73674.1 - 1.9e-42 143.9 0.0 2.4e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW73674.1 - 5.2e-05 23.0 0.0 7.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EIW73674.1 - 0.0056 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EIW73674.1 - 0.13 12.1 0.2 0.21 11.4 0.1 1.4 1 1 0 1 1 1 0 RWD domain Methyltransf_8 PF05148.10 EIW73675.1 - 7.7e-50 169.5 0.0 1.7e-25 89.9 0.0 2.3 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_23 PF13489.1 EIW73675.1 - 6.5e-05 22.7 0.0 0.00052 19.7 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW73675.1 - 0.001 19.5 0.0 0.56 10.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EIW73675.1 - 0.011 15.3 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain zf-met PF12874.2 EIW73676.1 - 9.1e-06 25.7 0.6 1.7e-05 24.8 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EIW73676.1 - 0.032 13.5 1.0 0.075 12.3 0.7 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Dynactin PF12455.3 EIW73677.1 - 7.1e-69 231.7 0.0 7.1e-69 231.7 0.0 3.7 5 1 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.20 EIW73677.1 - 2.8e-24 84.5 0.4 5.3e-24 83.7 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain TSC22 PF01166.13 EIW73677.1 - 0.14 12.1 0.0 0.14 12.1 0.0 7.4 8 1 1 9 9 9 0 TSC-22/dip/bun family SAC3_GANP PF03399.11 EIW73678.1 - 4.9e-14 52.3 0.0 6.2e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EIW73678.1 - 1.5e-11 44.2 0.0 2.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Dynamin_N PF00350.18 EIW73679.1 - 5.5e-10 39.3 0.0 1.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EIW73679.1 - 0.014 15.3 0.0 0.14 12.1 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF883 PF05957.8 EIW73680.1 - 0.02 15.3 14.1 3 8.2 0.1 4.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Methyltrans_RNA PF04452.9 EIW73680.1 - 0.07 12.2 2.6 0.1 11.6 1.8 1.2 1 0 0 1 1 1 0 RNA methyltransferase FliG_C PF01706.11 EIW73680.1 - 0.08 12.9 2.6 0.32 10.9 1.7 2.2 1 1 0 1 1 1 0 FliG C-terminal domain DUF4229 PF14012.1 EIW73680.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Baculo_PEP_C PF04513.7 EIW73680.1 - 0.15 11.8 0.4 50 3.7 0.0 3.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.8 EIW73680.1 - 0.24 10.4 3.1 3.3 6.6 0.7 2.3 1 1 1 2 2 2 0 TMPIT-like protein HTH_40 PF14493.1 EIW73680.1 - 0.28 11.4 3.3 39 4.5 0.0 3.4 2 1 0 3 3 3 0 Helix-turn-helix domain ATP-cone PF03477.11 EIW73680.1 - 0.37 11.2 6.1 4.2 7.8 0.2 3.3 3 0 0 3 3 3 0 ATP cone domain Peptidase_S46 PF10459.4 EIW73680.1 - 0.45 8.8 5.8 0.24 9.7 1.7 1.8 1 1 1 2 2 2 0 Peptidase S46 TipAS PF07739.8 EIW73680.1 - 8.4 6.7 11.1 5.5 7.3 0.2 3.5 2 1 0 3 3 3 0 TipAS antibiotic-recognition domain Ank_2 PF12796.2 EIW73681.1 - 1.7e-06 28.2 0.0 3.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIW73681.1 - 2.2e-05 24.0 0.5 0.00013 21.6 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EIW73681.1 - 2.9e-05 23.9 0.7 0.0025 17.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat zf-CCCH PF00642.19 EIW73681.1 - 0.0032 17.1 17.6 0.0039 16.8 1.8 2.9 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_5 PF13857.1 EIW73681.1 - 0.0055 16.9 0.0 0.39 11.0 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) zf-CCCH_2 PF14608.1 EIW73681.1 - 0.007 16.3 7.1 0.007 16.3 4.9 2.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type Ank_4 PF13637.1 EIW73681.1 - 0.02 15.4 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DDE_Tnp_1_2 PF13586.1 EIW73682.1 - 0.66 10.1 3.0 3.5 7.8 0.2 2.3 2 0 0 2 2 2 0 Transposase DDE domain Glyco_hydro_71 PF03659.9 EIW73683.1 - 1.1e-82 277.6 0.0 1.3e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_tran_WbsX PF14307.1 EIW73683.1 - 0.044 12.9 0.0 0.24 10.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase WbsX HLH PF00010.21 EIW73684.1 - 3.8e-09 36.0 0.7 7.2e-09 35.2 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PhoQ_Sensor PF08918.5 EIW73684.1 - 0.029 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoQ Sensor DivIVA PF05103.8 EIW73684.1 - 0.064 13.3 0.2 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 DivIVA protein E1_DerP2_DerF2 PF02221.10 EIW73685.1 - 6.1e-23 81.5 0.1 7.8e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EIW73685.1 - 0.0004 20.4 0.1 0.0008 19.4 0.0 1.5 2 0 0 2 2 2 1 ML-like domain Rieske PF00355.21 EIW73685.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Pterin_4a PF01329.14 EIW73686.1 - 4.7e-08 32.6 0.4 7.1e-07 28.8 0.2 2.5 1 1 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase PCI PF01399.22 EIW73687.1 - 2.1e-16 60.1 0.0 6.4e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 PCI domain Tet_res_leader PF08050.7 EIW73687.1 - 0.15 11.6 0.3 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Tetracycline resistance leader peptide MRP-S25 PF13741.1 EIW73688.1 - 1.6e-43 148.8 0.0 2.3e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 ECH PF00378.15 EIW73689.1 - 7.9e-37 126.6 0.2 9.9e-37 126.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EIW73689.1 - 0.062 13.4 0.2 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region WD40 PF00400.27 EIW73690.1 - 2.1e-84 274.6 19.7 6.3e-15 54.3 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW73690.1 - 3.2e-13 48.6 8.0 0.0025 16.0 0.2 4.5 2 2 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW73690.1 - 8.5e-08 31.3 0.7 0.14 10.8 0.1 4.6 2 2 3 5 5 5 4 Nup133 N terminal like eIF2A PF08662.6 EIW73690.1 - 0.00011 21.9 0.8 0.64 9.6 0.3 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EIW73690.1 - 0.0013 17.0 0.0 0.38 9.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain NYD-SP28_assoc PF14775.1 EIW73690.1 - 1.2 8.8 5.2 28 4.4 0.0 4.3 5 0 0 5 5 5 0 Sperm tail C-terminal domain RAI16-like PF10257.4 EIW73691.1 - 8.1e-81 271.6 0.0 2.1e-80 270.2 0.0 1.7 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein DcpS_C PF11969.3 EIW73692.1 - 1e-07 32.1 0.1 3.1e-07 30.6 0.1 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EIW73692.1 - 2.8e-06 27.7 0.1 1.9e-05 25.1 0.1 2.1 1 1 0 1 1 1 1 HIT domain PHP PF02811.14 EIW73693.1 - 9.8e-12 44.9 0.0 1.3e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 PHP domain Got1 PF04178.7 EIW73696.1 - 4.8e-19 68.6 12.5 5.4e-19 68.4 8.6 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 EIW73696.1 - 0.061 12.2 5.8 0.077 11.9 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF1212 PF06738.7 EIW73697.1 - 1.7e-40 138.5 4.1 1.7e-40 138.5 2.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIW73697.1 - 7.8e-18 64.6 2.7 7.8e-18 64.6 1.9 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) LAG1-DNAbind PF09271.6 EIW73698.1 - 1.2e-36 126.2 0.0 2.3e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 EIW73698.1 - 1.2e-17 64.1 0.0 4.3e-15 55.7 0.0 2.4 2 0 0 2 2 2 2 Beta-trefoil DNA-binding domain Beta_helix PF13229.1 EIW73699.1 - 5.2e-09 36.0 0.0 1.1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Right handed beta helix region Lectin_N PF03954.9 EIW73699.1 - 0.062 12.7 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain UQ_con PF00179.21 EIW73700.1 - 2.4e-44 150.1 0.1 2.7e-44 150.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW73700.1 - 0.00051 19.8 0.0 0.00061 19.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIW73700.1 - 0.0031 17.3 0.1 0.0089 15.9 0.1 1.8 1 1 1 2 2 2 1 RWD domain UreD PF01774.12 EIW73703.1 - 1.9e-49 168.0 0.0 2.3e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DAGK_cat PF00781.19 EIW73704.1 - 4.1e-21 74.7 0.0 6.9e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 EIW73704.1 - 0.074 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase Aa_trans PF01490.13 EIW73705.1 - 1.4e-67 227.9 28.6 1.7e-67 227.7 19.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EIW73705.1 - 0.00059 18.7 16.4 0.00059 18.7 11.4 2.2 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family YrhK PF14145.1 EIW73705.1 - 0.42 10.3 6.7 0.94 9.1 2.5 2.7 2 0 0 2 2 2 0 YrhK-like protein FGGY_C PF02782.11 EIW73706.1 - 3e-64 216.3 1.0 4.7e-64 215.6 0.7 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EIW73706.1 - 1.2e-62 211.4 0.0 1.5e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Aminotran_1_2 PF00155.16 EIW73711.1 - 1.4e-30 106.5 0.0 1.7e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II