# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- CBM_1 PF00734.18 CDO68064.1 - 3.4 7.7 8.1 1.4e+02 2.6 8.1 2.9 1 1 0 1 1 1 0 Fungal cellulose binding domain Aconitase PF00330.20 CDO68065.1 - 4.7e-112 375.3 0.0 6.8e-111 371.5 0.0 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDO68065.1 - 9.2e-20 71.3 0.0 1.7e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 CDO68065.1 - 0.012 14.4 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MIB_HERC2 PF06701.13 CDO68065.1 - 0.13 12.5 1.3 0.3 11.4 1.3 1.5 1 0 0 1 1 1 0 Mib_herc2 MCM PF00493.23 CDO68065.1 - 0.22 10.6 0.1 0.38 9.8 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain AMP-binding PF00501.28 CDO68066.1 - 1.7e-92 310.3 0.0 2.2e-92 309.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDO68066.1 - 0.00012 23.0 0.1 0.00049 21.0 0.0 2.1 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2104 PF09877.9 CDO68066.1 - 0.032 14.5 0.1 0.088 13.1 0.1 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) p450 PF00067.22 CDO68067.1 - 1.5e-58 198.6 0.0 1.9e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Biliv-reduc_cat PF09166.10 CDO68068.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Biliverdin reductase, catalytic RVT_1 PF00078.27 CDO68069.1 - 9e-24 84.2 0.0 1.7e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO68069.1 - 1.7e-08 34.8 0.0 3.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.6 CDO68069.1 - 2.2e-05 24.3 0.1 5e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDO68069.1 - 0.0004 20.0 1.2 0.0011 18.5 0.7 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family FlgN PF05130.12 CDO68071.1 - 0.19 12.3 0.4 0.61 10.6 0.1 2.0 2 0 0 2 2 2 0 FlgN protein EAP30 PF04157.16 CDO68073.1 - 5.6e-34 117.5 0.0 8.7e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 CDO68073.1 - 1.3e-20 73.3 0.0 2.4e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 CDO68073.1 - 0.00017 20.8 11.5 0.026 13.9 1.5 2.6 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 CDO68073.1 - 0.78 9.8 5.0 0.67 10.0 0.9 2.2 2 0 0 2 2 2 0 Double zinc ribbon Vps36-NZF-N PF16988.5 CDO68073.1 - 3.9 6.9 12.8 0.04 13.3 2.5 2.7 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 CDO68073.1 - 5.9 7.0 10.6 4 7.6 0.6 3.1 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger VCBS PF13517.6 CDO68076.1 - 0.00046 20.7 4.0 0.0028 18.2 0.1 3.6 3 1 2 5 5 5 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF1687 PF07955.11 CDO68077.1 - 1.9e-18 67.1 0.0 2.4e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Prefoldin PF02996.17 CDO68078.1 - 6.9e-27 93.7 0.4 8.5e-26 90.2 0.4 2.1 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 CDO68078.1 - 0.087 12.8 1.5 0.23 11.5 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.11 CDO68078.1 - 0.1 13.2 2.9 0.51 10.9 1.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RRM_1 PF00076.22 CDO68079.1 - 1.2e-65 217.3 0.0 1.7e-19 69.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDO68079.1 - 9.7e-06 25.4 0.0 0.053 13.4 0.0 3.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 CDO68079.1 - 0.0027 17.5 0.0 2 8.2 0.0 4.3 5 0 0 5 5 5 1 Rrp7 RRM-like N-terminal domain PHM7_cyt PF14703.6 CDO68079.1 - 0.0035 17.6 2.1 45 4.2 0.1 5.9 5 2 0 6 6 6 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 CDO68079.1 - 0.016 15.2 0.0 22 5.1 0.0 3.8 4 0 0 4 4 4 0 RNA binding motif Nup35_RRM_2 PF14605.6 CDO68079.1 - 0.05 13.6 0.0 11 6.1 0.0 3.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif STE3 PF02076.15 CDO68081.1 - 6.9e-102 340.5 18.2 8.2e-102 340.3 18.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor MFS_1 PF07690.16 CDO68082.1 - 8.8e-06 24.9 2.5 9e-06 24.8 2.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO68082.1 - 0.011 14.6 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter DUF3325 PF11804.8 CDO68082.1 - 0.027 14.6 0.3 0.038 14.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) Sugar_tr PF00083.24 CDO68083.1 - 2.8e-13 49.5 4.4 2.8e-13 49.5 4.4 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO68083.1 - 4.7e-13 48.8 29.4 8e-13 48.0 29.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 CDO68084.1 - 1.6e-17 63.4 0.1 5.5e-09 36.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDO68084.1 - 3.3e-12 46.5 0.0 2.6e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 CDO68084.1 - 1.6e-06 28.1 0.0 0.024 14.7 0.0 2.3 2 0 0 2 2 2 2 SLIDE PCI PF01399.27 CDO68085.1 - 1.3e-08 35.2 0.1 4.4e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 PCI domain EF-hand_14 PF17959.1 CDO68085.1 - 0.064 13.6 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain DUF3562 PF12085.8 CDO68085.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) MFS_1 PF07690.16 CDO68086.1 - 4.1e-08 32.5 14.1 4.8e-08 32.3 14.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO68086.1 - 0.042 12.7 9.4 0.052 12.4 9.4 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.16 CDO68087.1 - 3.7e-07 29.4 15.3 8e-06 25.0 16.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 CDO68087.1 - 0.096 11.0 7.4 0.11 10.8 7.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Abhydrolase_6 PF12697.7 CDO68088.1 - 2.6e-11 44.6 1.9 3.5e-11 44.1 1.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family YkyA PF10368.9 CDO68090.1 - 0.045 13.4 1.3 0.078 12.6 1.3 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein FH2 PF02181.23 CDO68090.1 - 0.12 11.5 1.2 0.24 10.5 1.2 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain MnmE_helical PF12631.7 CDO68090.1 - 0.12 12.5 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 MnmE helical domain FlgN PF05130.12 CDO68090.1 - 0.13 12.7 6.7 0.28 11.7 6.7 1.6 1 0 0 1 1 1 0 FlgN protein Spc7 PF08317.11 CDO68090.1 - 0.14 11.0 4.4 0.21 10.4 4.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CorA PF01544.18 CDO68090.1 - 0.45 9.8 1.8 0.72 9.1 1.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_MLP1_2 PF07926.12 CDO68090.1 - 0.6 10.2 6.4 1.3 9.1 6.4 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1515 PF07439.11 CDO68090.1 - 1.6 8.8 3.4 59 3.7 3.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4200 PF13863.6 CDO68090.1 - 1.9 8.9 4.7 4.4 7.7 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) HSCB_C PF07743.13 CDO68090.1 - 7.8 7.1 9.9 3 8.4 3.0 2.5 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain STE3 PF02076.15 CDO68091.1 - 1.2e-05 24.7 3.6 1.5e-05 24.4 3.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF1391 PF07151.12 CDO68091.1 - 0.17 11.7 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1391) Mucin15 PF15672.5 CDO68093.1 - 0.26 10.7 2.8 0.57 9.6 2.5 1.7 1 1 1 2 2 2 0 Cell-membrane associated Mucin15 zf-C2H2 PF00096.26 CDO68094.1 - 3.7e-06 27.1 15.9 0.00024 21.4 1.6 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO68094.1 - 0.00033 21.3 9.9 0.08 13.8 2.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDO68094.1 - 0.0012 19.2 3.4 0.0012 19.2 3.4 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 CDO68094.1 - 2.6 7.9 5.2 5.4 6.9 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DBR1 PF05011.13 CDO68096.1 - 0.0002 21.8 0.0 0.00031 21.2 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos_2 PF12850.7 CDO68096.1 - 0.01 16.1 0.0 0.021 15.0 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Brix PF04427.18 CDO68097.1 - 4.3e-29 102.0 0.0 1.5e-25 90.5 0.0 2.2 1 1 0 1 1 1 1 Brix domain IMUP PF15761.5 CDO68097.1 - 3.1 8.5 7.2 14 6.5 0.2 2.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein BTB PF00651.31 CDO68099.1 - 0.057 13.7 0.0 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain BTB PF00651.31 CDO68100.1 - 0.00021 21.5 0.0 0.00033 20.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF746 PF05344.11 CDO68101.1 - 0.16 11.8 0.2 0.4 10.5 0.1 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) 2OG-FeII_Oxy_3 PF13640.6 CDO68102.1 - 6.2e-11 43.1 0.1 1.7e-10 41.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CDO68103.1 - 1e-08 35.9 2.1 1.3e-08 35.6 0.2 2.1 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 CDO68103.1 - 0.00094 19.8 0.0 0.0018 18.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 CDO68104.1 - 7.5e-41 140.2 0.0 3.9e-17 62.5 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDO68104.1 - 6.4e-13 48.6 0.3 8.2e-05 22.0 0.1 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase RIO1 PF01163.22 CDO68104.1 - 0.24 11.0 0.1 0.47 10.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 CDO68104.1 - 0.33 9.9 0.0 0.48 9.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Asp PF00026.23 CDO68106.1 - 3.6e-18 66.1 0.2 4.5e-15 55.9 0.2 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CDO68106.1 - 2.6e-05 24.8 5.7 0.0057 17.3 1.3 3.5 3 2 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 CDO68106.1 - 0.00018 22.0 0.8 0.081 13.5 0.3 3.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 CDO68106.1 - 0.022 15.0 0.3 0.92 9.7 0.1 2.3 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal WD40 PF00400.32 CDO68107.1 - 1.2e-36 124.0 13.0 3e-11 43.7 0.6 7.0 5 1 1 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO68107.1 - 8e-14 51.7 0.1 1.2e-06 28.7 0.0 4.2 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDO68107.1 - 8.5e-09 34.6 1.1 0.0041 15.8 0.0 3.8 3 1 1 4 4 4 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CDO68107.1 - 0.0014 17.6 0.0 2.6 6.9 0.0 3.1 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 CDO68107.1 - 0.0058 15.2 0.1 0.016 13.7 0.0 1.7 2 0 0 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 CDO68107.1 - 0.0097 14.9 0.2 6.8 5.6 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDO68107.1 - 0.02 14.8 0.0 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 CDO68107.1 - 0.065 13.2 1.1 0.13 12.3 1.1 1.5 1 0 0 1 1 1 0 LisH DUF2390 PF09523.10 CDO68108.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Sad1_UNC PF07738.13 CDO68111.1 - 2.4e-10 40.6 0.0 8.6e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Plavaka PF18759.1 CDO68115.1 - 5.5e-113 377.5 0.0 8.1e-113 376.9 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 CDO68115.1 - 0.52 9.7 10.5 0.84 9.0 10.5 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CDO68115.1 - 4.1 6.6 12.5 6.7 5.9 12.5 1.2 1 0 0 1 1 1 0 BUD22 F-box-like PF12937.7 CDO68118.1 - 0.003 17.4 0.1 0.0089 15.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO68118.1 - 1.9 8.5 8.3 13 5.8 0.3 3.7 2 2 1 3 3 3 0 F-box domain DNA_primase_S PF01896.19 CDO68119.1 - 2.9e-55 187.1 0.0 4.4e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 DNA primase small subunit Transposase_21 PF02992.14 CDO68121.1 - 5.2e-16 58.5 0.0 9.6e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Myc_N PF01056.18 CDO68123.1 - 0.0026 17.7 1.2 0.0035 17.3 1.2 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Tub_N PF16322.5 CDO68123.1 - 0.0029 18.0 1.3 0.0045 17.4 1.3 1.3 1 0 0 1 1 1 1 Tubby N-terminal TAP42 PF04177.12 CDO68123.1 - 0.027 13.6 0.9 0.04 13.0 0.9 1.3 1 0 0 1 1 1 0 TAP42-like family TAL_effector PF03377.13 CDO68123.1 - 0.047 14.0 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 TAL effector repeat RRN3 PF05327.11 CDO68123.1 - 0.11 11.0 3.0 0.13 10.8 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CDO68123.1 - 0.47 8.5 5.1 0.63 8.1 5.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 CDO68123.1 - 0.66 10.4 4.2 2.9 8.3 3.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 CDO68123.1 - 1.6 9.2 11.8 3.5 8.1 11.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LAT PF15234.6 CDO68123.1 - 3 7.5 9.5 5.8 6.6 9.4 1.6 1 1 0 1 1 1 0 Linker for activation of T-cells NOA36 PF06524.12 CDO68123.1 - 6.5 6.0 8.5 9.5 5.4 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein CM_2 PF01817.21 CDO68124.1 - 0.00026 21.3 1.2 0.00047 20.5 1.2 1.4 1 1 0 1 1 1 1 Chorismate mutase type II Integrase_H2C2 PF17921.1 CDO68125.1 - 1.4e-17 63.6 3.0 2.6e-17 62.7 3.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO68125.1 - 5.5e-09 36.2 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CDO68125.1 - 0.08 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 DDE domain CM_2 PF01817.21 CDO68126.1 - 0.00068 19.9 0.6 0.0013 19.1 0.6 1.4 1 0 0 1 1 1 1 Chorismate mutase type II RT_RNaseH_2 PF17919.1 CDO68127.1 - 4.9e-12 45.8 0.0 1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDO68127.1 - 1.8e-10 40.8 0.0 4.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CDO68127.1 - 9e-10 38.8 0.0 1.9e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Nop10p PF04135.12 CDO68127.1 - 0.0077 16.3 3.0 2.5 8.2 0.1 2.9 3 0 0 3 3 3 2 Nucleolar RNA-binding protein, Nop10p family gag-asp_proteas PF13975.6 CDO68127.1 - 0.096 13.3 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO68127.1 - 0.17 12.6 0.0 0.38 11.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 CDO68128.1 - 0.028 15.1 0.0 0.085 13.5 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 CDO68128.1 - 0.16 12.6 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotran_gag_2 PF14223.6 CDO68129.1 - 5.5e-05 22.8 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type U79_P34 PF03064.16 CDO68129.1 - 0.077 12.3 0.4 0.1 11.9 0.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Retrotran_gag_2 PF14223.6 CDO68130.1 - 0.066 12.9 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DEP PF00610.21 CDO68130.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) p450 PF00067.22 CDO68134.1 - 1.9e-70 237.9 0.0 2.6e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CDO68135.1 - 1.6e-72 244.8 0.0 2.2e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tubulin PF00091.25 CDO68136.1 - 3.2e-66 223.3 0.0 4.2e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDO68136.1 - 2.2e-46 157.1 0.0 3.3e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDO68136.1 - 0.00043 20.0 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CDO68136.1 - 0.057 13.7 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Lipase_3 PF01764.25 CDO68136.1 - 0.14 12.0 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Tubulin PF00091.25 CDO68137.1 - 6.4e-65 219.1 0.0 8.9e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDO68137.1 - 3.2e-47 159.8 0.0 5e-47 159.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDO68137.1 - 7.4e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CDO68137.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Abhydrolase_3 PF07859.13 CDO68138.1 - 3.8e-28 98.8 0.1 4.3e-20 72.5 0.0 2.9 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDO68138.1 - 8.8e-05 21.5 0.1 0.00046 19.1 0.1 2.2 1 1 0 1 1 1 1 Steryl acetyl hydrolase Protoglobin PF11563.8 CDO68139.1 - 1.6e-40 138.6 0.0 1.9e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protoglobin NOP19 PF10863.8 CDO68140.1 - 0.021 14.6 0.0 0.021 14.6 0.0 4.0 4 0 0 4 4 4 0 Nucleolar protein 19 G-patch_2 PF12656.7 CDO68140.1 - 0.073 13.2 0.0 0.073 13.2 0.0 3.6 4 0 0 4 4 4 0 G-patch domain SIP1 PF04938.12 CDO68141.1 - 2.4e-26 92.8 0.1 3e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) GPI-anchored PF10342.9 CDO68142.1 - 7.4e-12 45.9 0.6 7.4e-12 45.9 0.6 2.0 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family BetaGal_dom2 PF10435.9 CDO68142.1 - 0.021 14.6 1.7 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 Beta-galactosidase, domain 2 QRPTase_C PF01729.19 CDO68143.1 - 7.6e-50 169.0 0.0 9.4e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 CDO68143.1 - 6.5e-20 71.0 0.1 2e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Amidohydro_2 PF04909.14 CDO68144.1 - 5.9e-23 82.1 0.3 1.2e-16 61.3 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase TatD_DNase PF01026.21 CDO68144.1 - 0.21 10.9 0.0 0.81 9.0 0.0 1.9 3 0 0 3 3 3 0 TatD related DNase ECH_1 PF00378.20 CDO68145.1 - 2.6e-56 190.8 0.0 2.6e-56 190.8 0.0 2.1 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDO68145.1 - 4.4e-28 98.8 3.8 6.6e-27 94.9 0.1 3.6 3 1 0 3 3 3 1 Enoyl-CoA hydratase/isomerase NRBF2 PF08961.10 CDO68145.1 - 0.0078 15.8 2.4 0.0078 15.8 2.4 2.0 2 0 0 2 2 1 1 Nuclear receptor-binding factor 2, autophagy regulator Cep57_CLD_2 PF14197.6 CDO68145.1 - 0.026 14.6 12.2 1 9.5 5.9 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF1515 PF07439.11 CDO68145.1 - 0.32 11.0 4.4 0.23 11.5 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) YabA PF06156.13 CDO68145.1 - 0.34 11.6 3.2 0.59 10.8 2.2 1.9 1 1 1 2 2 2 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 CDO68145.1 - 0.37 10.3 5.0 0.67 9.5 5.0 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FUSC PF04632.12 CDO68145.1 - 0.46 9.0 9.5 0.83 8.1 9.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 CDO68145.1 - 0.48 10.9 7.6 0.2 12.1 3.9 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Spc7 PF08317.11 CDO68145.1 - 1.6 7.6 5.7 2.6 6.9 5.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 CDO68145.1 - 5 7.2 5.9 2.2 8.4 1.8 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec10 PF07393.11 CDO68146.1 - 1.1e-208 695.2 0.1 4.3e-173 577.5 0.0 2.9 2 1 0 2 2 2 2 Exocyst complex component Sec10 Peptidase_S46 PF10459.9 CDO68146.1 - 0.0062 15.2 2.0 0.014 14.1 2.0 1.6 1 0 0 1 1 1 1 Peptidase S46 DUF1664 PF07889.12 CDO68146.1 - 0.0072 16.4 1.2 0.028 14.4 1.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) I_LWEQ PF01608.17 CDO68146.1 - 0.016 15.4 1.8 0.09 13.0 0.2 2.5 2 0 0 2 2 2 0 I/LWEQ domain DUF812 PF05667.11 CDO68146.1 - 0.049 12.5 1.3 0.058 12.3 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Filament PF00038.21 CDO68146.1 - 0.27 10.8 3.5 0.55 9.8 3.5 1.5 1 0 0 1 1 1 0 Intermediate filament protein OmpH PF03938.14 CDO68146.1 - 4.2 7.7 7.5 6.3 7.1 3.7 2.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ytp1 PF10355.9 CDO68147.1 - 7.5e-108 359.9 6.9 1e-107 359.5 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CDO68147.1 - 4.6e-15 55.3 0.6 4.6e-15 55.3 0.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Dimer_Tnp_hAT PF05699.14 CDO68148.1 - 4e-08 32.9 0.0 7.2e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Myb_DNA-bind_3 PF12776.7 CDO68149.1 - 7.3e-09 36.5 0.0 1.7e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Thiol_cytolys_C PF17440.2 CDO68149.1 - 0.12 12.6 0.8 3 8.1 0.3 2.3 1 1 1 2 2 2 0 Thiol-activated cytolysin beta sandwich domain AIP3 PF03915.13 CDO68150.1 - 1.7e-138 462.2 13.6 1.3e-136 455.9 13.6 2.3 1 1 0 1 1 1 1 Actin interacting protein 3 Syntaxin-6_N PF09177.11 CDO68150.1 - 0.012 16.2 14.2 0.17 12.4 1.7 4.6 3 1 1 4 4 4 0 Syntaxin 6, N-terminal DIRP PF06584.13 CDO68150.1 - 0.065 13.4 2.8 0.17 12.1 0.1 2.8 2 0 0 2 2 2 0 DIRP WXG100 PF06013.12 CDO68150.1 - 0.072 13.3 8.3 6.5 7.1 0.8 3.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG ISG65-75 PF11727.8 CDO68150.1 - 0.3 10.3 1.3 0.61 9.3 0.9 1.7 1 1 0 1 1 1 0 Invariant surface glycoprotein FlaC_arch PF05377.11 CDO68150.1 - 0.48 10.9 13.5 0.75 10.2 0.4 4.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 CDO68150.1 - 2.3 8.3 11.9 1.6 8.7 5.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ApoO PF09769.9 CDO68150.1 - 2.8 7.9 5.3 1.8 8.5 0.3 3.1 3 1 1 4 4 4 0 Apolipoprotein O CdvA PF18822.1 CDO68150.1 - 3.5 7.5 11.9 1.5 8.7 0.1 4.0 3 1 1 4 4 4 0 CdvA-like coiled-coil domain KfrA_N PF11740.8 CDO68150.1 - 3.7 8.3 11.1 4.7 7.9 0.1 4.5 5 0 0 5 5 5 0 Plasmid replication region DNA-binding N-term DUF5082 PF16888.5 CDO68150.1 - 4.3 7.6 11.3 2.2 8.6 0.5 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) EMP24_GP25L PF01105.24 CDO68150.1 - 6.6 6.6 7.7 1.7 8.6 2.4 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD End3 PF12761.7 CDO68150.1 - 7 6.8 9.5 1.5 8.9 3.7 2.9 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Lectin_N PF03954.14 CDO68150.1 - 7.8 6.3 6.5 5.2 6.8 2.6 2.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain NAGLU PF05089.12 CDO68151.1 - 0.11 11.4 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Ustilago_mating PF05722.12 CDO68152.1 - 0.025 14.1 3.2 0.032 13.8 3.2 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein GREB1 PF15782.5 CDO68152.1 - 2.3 5.2 3.8 2.7 5.0 3.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MAP65_ASE1 PF03999.12 CDO68152.1 - 4.9 5.7 5.8 6.3 5.4 5.8 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) He_PIG PF05345.12 CDO68153.1 - 5.1e-10 39.4 19.3 9.5e-07 28.9 5.2 5.0 4 0 0 4 4 4 3 Putative Ig domain Sarcoglycan_2 PF05510.13 CDO68153.1 - 0.081 11.7 0.0 5.3 5.7 0.0 2.7 3 0 0 3 3 3 0 Sarcoglycan alpha/epsilon Rib PF08428.10 CDO68153.1 - 0.081 12.9 0.3 0.17 11.9 0.3 1.5 1 0 0 1 1 1 0 Rib/alpha-like repeat DDE_1 PF03184.19 CDO68154.1 - 6.4e-35 120.4 0.0 1.1e-34 119.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease MFS_1 PF07690.16 CDO68154.1 - 1.1e-10 41.1 25.7 7.3e-09 35.0 21.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_Tnp_Tc5 PF03221.16 CDO68154.1 - 1.1e-10 41.4 0.0 2.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF4817 PF16087.5 CDO68154.1 - 0.02 14.7 0.0 0.055 13.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) OPT PF03169.15 CDO68155.1 - 1.9e-146 489.2 40.4 2.2e-146 489.1 40.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Dynein_light PF01221.18 CDO68156.1 - 2.6e-40 136.6 1.4 3e-40 136.4 1.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4320 PF14208.6 CDO68156.1 - 0.13 12.3 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) Macoilin PF09726.9 CDO68159.1 - 9.8 4.6 6.4 13 4.2 6.4 1.1 1 0 0 1 1 1 0 Macoilin family DHBP_synthase PF00926.19 CDO68160.1 - 4.4e-16 59.0 0.0 6.4e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Mito_carr PF00153.27 CDO68161.1 - 5.8e-32 109.5 5.4 2.8e-17 62.4 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein COesterase PF00135.28 CDO68162.1 - 2.1e-84 284.3 0.0 7.8e-83 279.1 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CDO68162.1 - 0.00072 19.1 0.7 0.0012 18.4 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CDO68162.1 - 0.0051 16.7 2.0 0.0087 15.9 0.1 2.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold DUF1749 PF08538.10 CDO68162.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) COesterase PF00135.28 CDO68163.1 - 1.4e-23 83.6 0.0 1.7e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 CDO68164.1 - 1.8e-08 33.7 0.0 0.00093 18.2 0.0 2.7 2 1 0 2 2 2 2 Carboxylesterase family zf-RING_11 PF17123.5 CDO68165.1 - 2.4e-05 24.0 2.2 0.0067 16.2 0.2 2.4 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_2 PF13639.6 CDO68165.1 - 4.8e-05 23.6 0.7 0.0025 18.1 0.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CDO68165.1 - 0.0011 19.1 2.7 0.0034 17.6 2.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDO68165.1 - 0.006 16.4 0.2 0.018 14.9 0.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDO68165.1 - 0.011 15.5 4.3 0.042 13.7 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO68165.1 - 0.021 14.8 0.9 0.098 12.7 0.2 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 CDO68165.1 - 0.062 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CDO68165.1 - 0.092 12.4 0.2 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CDO68165.1 - 0.4 10.9 1.7 1.5 9.0 0.2 2.4 3 0 0 3 3 3 0 FANCL C-terminal domain DUF5585 PF17823.1 CDO68166.1 - 0.22 10.4 40.4 0.31 9.9 40.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Macoilin PF09726.9 CDO68166.1 - 2.1 6.8 8.0 2.4 6.6 8.0 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_32N PF00251.20 CDO68168.1 - 8.4e-80 268.6 1.6 1e-79 268.3 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CDO68168.1 - 3.5e-09 36.9 0.0 7.3e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal LRR_8 PF13855.6 CDO68169.1 - 1.7e-09 37.3 1.8 4.5e-09 35.9 1.8 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 CDO68169.1 - 7.1e-07 29.5 1.7 2.2e-06 27.9 0.4 2.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDO68169.1 - 0.027 14.5 3.2 36 4.8 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CDO68169.1 - 0.18 12.5 0.9 79 4.4 0.0 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat Glyco_hydro_16 PF00722.21 CDO68170.1 - 1.5e-32 112.5 0.0 2e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Egh16-like PF11327.8 CDO68171.1 - 2.5e-06 28.1 2.8 2.5e-06 28.1 2.8 2.2 1 1 1 2 2 2 1 Egh16-like virulence factor SWI-SNF_Ssr4 PF08549.10 CDO68171.1 - 1.2 7.6 5.5 1.4 7.5 5.5 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Fungal_trans PF04082.18 CDO68172.1 - 1.7e-25 89.5 0.0 3.8e-25 88.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain PPP4R2 PF09184.11 CDO68173.1 - 4 7.0 7.7 7.3 6.1 7.7 1.5 1 0 0 1 1 1 0 PPP4R2 Methyltransf_10 PF05971.12 CDO68174.1 - 2.2e-30 106.0 0.0 3.2e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase BTB PF00651.31 CDO68176.1 - 6.4e-06 26.4 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Thiolase_N PF00108.23 CDO68177.1 - 1e-81 274.2 2.4 1e-81 274.2 2.4 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDO68177.1 - 9.1e-43 144.8 0.5 1.9e-42 143.8 0.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CDO68177.1 - 0.00056 19.6 2.3 0.072 12.7 0.3 3.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain WES_acyltransf PF03007.16 CDO68178.1 - 1.4e-21 77.5 0.3 3.1e-21 76.3 0.2 1.4 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 CDO68178.1 - 1e-08 35.3 0.0 1.9e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1298) HEAT PF02985.22 CDO68179.1 - 1.3e-14 53.0 14.0 0.024 14.9 0.0 9.9 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 CDO68179.1 - 9.9e-14 51.5 15.2 0.0011 19.4 0.1 11.3 12 1 1 13 13 13 2 HEAT-like repeat HEAT_2 PF13646.6 CDO68179.1 - 1.2e-12 48.1 6.8 0.025 14.9 0.7 7.2 6 2 2 8 8 8 5 HEAT repeats IBN_N PF03810.19 CDO68179.1 - 8.4e-10 38.4 0.9 3.1e-07 30.2 0.2 3.5 2 1 1 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.7 CDO68179.1 - 2.7e-08 34.0 0.1 0.0026 17.8 0.0 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 CDO68179.1 - 1.1e-06 28.0 1.6 0.0043 16.2 0.0 4.4 2 2 3 5 5 5 1 Interferon-related developmental regulator (IFRD) RIX1 PF08167.12 CDO68179.1 - 0.00096 18.9 0.5 0.17 11.6 0.0 4.3 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 CDO68179.1 - 0.0011 19.5 0.1 0.33 11.6 0.0 4.5 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region XPC-binding PF09280.11 CDO68179.1 - 0.14 11.9 3.4 4.1 7.2 0.0 4.0 3 0 0 3 3 3 0 XPC-binding domain Arm PF00514.23 CDO68179.1 - 8.7 6.5 9.4 1.2e+02 3.0 0.0 6.0 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat ASL_C PF08328.11 CDO68180.1 - 0.025 14.7 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Phosducin PF02114.16 CDO68181.1 - 1.1e-14 54.0 0.0 1.2e-05 24.4 0.0 3.1 3 0 0 3 3 3 3 Phosducin ERp29 PF07749.12 CDO68181.1 - 0.039 14.9 0.3 0.08 13.9 0.3 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Ribosomal_L30 PF00327.20 CDO68182.1 - 0.027 14.4 0.4 0.096 12.6 0.0 2.1 3 0 0 3 3 3 0 Ribosomal protein L30p/L7e MF_alpha_N PF05436.11 CDO68183.1 - 0.043 13.7 0.3 0.062 13.2 0.3 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUF4407 PF14362.6 CDO68184.1 - 0.0039 16.6 1.3 0.038 13.3 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) FlxA PF14282.6 CDO68184.1 - 0.0086 16.1 1.2 0.33 11.0 0.1 2.9 3 0 0 3 3 3 1 FlxA-like protein CENP-Q PF13094.6 CDO68184.1 - 0.015 15.5 7.4 0.42 10.8 5.2 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6_N PF17675.1 CDO68184.1 - 0.023 15.2 3.6 0.023 15.2 3.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region FUSC PF04632.12 CDO68184.1 - 0.082 11.4 2.0 0.13 10.8 2.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GPO PF05929.11 CDO68184.1 - 0.13 11.9 0.7 0.21 11.2 0.7 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1192 PF06698.11 CDO68184.1 - 3.3 7.8 8.1 3.1 7.9 1.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) CdvA PF18822.1 CDO68184.1 - 3.4 7.5 6.2 0.33 10.8 0.8 2.0 3 0 0 3 3 3 0 CdvA-like coiled-coil domain zf-C2HC5 PF06221.13 CDO68185.1 - 1e-16 60.6 5.3 1.8e-16 59.8 5.3 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.6 CDO68185.1 - 0.021 14.2 1.6 0.71 9.4 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Macoilin PF09726.9 CDO68186.1 - 0.31 9.6 2.5 0.36 9.3 2.5 1.2 1 0 0 1 1 1 0 Macoilin family GATA PF00320.27 CDO68187.1 - 1.4e-08 34.2 5.7 2.3e-08 33.5 5.7 1.4 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 CDO68187.1 - 0.015 15.3 1.6 0.042 13.9 1.6 1.7 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf Lipase_GDSL PF00657.22 CDO68188.1 - 4.2e-06 26.9 0.0 9.7e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CDO68188.1 - 0.00017 22.1 0.1 0.00067 20.1 0.0 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family GST_N PF02798.20 CDO68190.1 - 4.7e-21 74.9 0.0 8.4e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CDO68190.1 - 4.1e-16 59.2 0.0 7.2e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO68190.1 - 5.2e-12 45.9 0.0 9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDO68190.1 - 3.5e-11 43.2 0.0 4.7e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO68190.1 - 2.1e-05 24.5 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO68190.1 - 2.2e-05 24.5 0.0 3.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Frigida PF07899.11 CDO68191.1 - 0.017 14.4 0.4 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Frigida-like protein Mistic PF11458.8 CDO68191.1 - 0.02 14.9 0.0 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Membrane-integrating protein Mistic OSK PF17182.4 CDO68191.1 - 0.031 13.5 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 OSK domain GAGBD PF16828.5 CDO68191.1 - 0.19 11.8 0.0 14 5.7 0.0 2.1 2 0 0 2 2 2 0 GAG-binding domain on surface antigen DHO_dh PF01180.21 CDO68192.1 - 2.3e-92 309.4 0.0 2.8e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CDO68192.1 - 0.015 14.4 2.6 0.73 8.8 4.4 2.5 2 1 0 2 2 2 0 FMN-dependent dehydrogenase NMO PF03060.15 CDO68192.1 - 0.049 13.0 0.2 0.22 10.9 0.1 2.0 2 0 0 2 2 2 0 Nitronate monooxygenase DUF3911 PF13050.6 CDO68193.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3911) Velvet PF11754.8 CDO68197.1 - 7.3e-33 114.6 0.0 1.5e-32 113.5 0.0 1.5 1 1 0 1 1 1 1 Velvet factor NOA36 PF06524.12 CDO68197.1 - 0.2 10.9 0.7 0.39 10.0 0.7 1.4 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 CDO68197.1 - 0.68 10.3 4.7 1.5 9.2 4.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 CDO68197.1 - 0.69 7.9 2.5 0.97 7.4 2.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ion_trans PF00520.31 CDO68198.1 - 0.01 15.1 1.4 0.017 14.3 1.4 1.4 1 0 0 1 1 1 1 Ion transport protein ComA PF02679.15 CDO68198.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) ERG4_ERG24 PF01222.17 CDO68200.1 - 3.5e-131 437.9 26.3 4e-131 437.7 26.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CDO68200.1 - 3.8e-06 26.6 2.4 7.7e-06 25.6 2.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CDO68200.1 - 0.011 16.1 0.3 0.011 16.1 0.3 3.9 3 2 2 5 5 5 0 Phospholipid methyltransferase ICMT PF04140.14 CDO68200.1 - 0.018 15.4 1.7 0.045 14.2 0.0 2.5 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Lamprin PF06403.11 CDO68200.1 - 0.025 14.6 0.1 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 Lamprin Sulfate_transp PF00916.20 CDO68200.1 - 0.15 10.8 4.5 0.17 10.6 3.4 1.5 1 1 0 1 1 1 0 Sulfate permease family DWNN PF08783.11 CDO68201.1 - 1.1e-29 102.5 0.7 3.2e-29 101.0 0.5 1.9 2 0 0 2 2 2 1 DWNN domain zf-C3HC4_3 PF13920.6 CDO68201.1 - 0.0035 17.2 4.8 0.0065 16.3 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_2 PF13696.6 CDO68201.1 - 0.0044 16.8 0.9 0.0093 15.8 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 CDO68201.1 - 0.039 13.8 7.3 0.074 12.9 7.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trm112p PF03966.16 CDO68201.1 - 0.068 13.7 0.1 0.2 12.2 0.1 1.8 1 0 0 1 1 1 0 Trm112p-like protein DUF5320 PF17253.2 CDO68201.1 - 0.15 13.1 10.9 0.97 10.5 2.8 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5320) Borrelia_P83 PF05262.11 CDO68201.1 - 0.4 9.1 5.4 0.65 8.4 5.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-RING_5 PF14634.6 CDO68201.1 - 0.51 10.3 6.2 0.97 9.5 6.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 CDO68201.1 - 0.72 10.2 11.8 0.047 14.0 6.0 1.9 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 CDO68201.1 - 1.2 9.2 5.6 2.3 8.3 5.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CDO68201.1 - 1.4 8.9 6.9 3.3 7.7 6.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Efg1 PF10153.9 CDO68201.1 - 3.6 8.0 8.3 1 9.7 1.5 2.4 2 0 0 2 2 2 0 rRNA-processing protein Efg1 Atg14 PF10186.9 CDO68201.1 - 4.3 6.3 6.9 12 4.8 6.9 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CDO68201.1 - 8.6 5.6 17.2 17 4.7 17.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vps5 PF09325.10 CDO68202.1 - 6.6e-67 225.5 4.2 9.5e-67 225.0 4.2 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CDO68202.1 - 1.4e-27 95.9 0.3 4.4e-26 91.1 0.0 2.3 2 0 0 2 2 2 1 PX domain BAR PF03114.18 CDO68202.1 - 2.1e-05 24.3 3.1 2.8e-05 23.9 3.1 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 CDO68202.1 - 0.0027 17.5 3.3 0.024 14.4 3.3 2.1 1 1 0 1 1 1 1 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 CDO68202.1 - 0.023 14.1 0.9 0.22 11.0 0.9 2.1 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Arfaptin PF06456.13 CDO68202.1 - 0.053 13.1 2.4 0.32 10.5 2.4 1.9 1 1 0 1 1 1 0 Arfaptin-like domain CLZ PF16526.5 CDO68202.1 - 0.074 13.4 1.7 1.5 9.2 0.1 3.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels p450 PF00067.22 CDO68203.1 - 1.3e-62 212.1 0.0 1.7e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3837 PF12939.7 CDO68203.1 - 0.15 12.5 0.0 7.7 7.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) PMT PF02366.18 CDO68204.1 - 6.3e-80 268.3 18.3 6.3e-80 268.3 18.3 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CDO68204.1 - 8.6e-52 175.6 3.6 8.6e-52 175.6 3.6 3.9 2 2 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CDO68204.1 - 4e-16 59.4 0.1 6.2e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 CDO68204.1 - 1.1e-06 29.0 14.2 1.1e-06 29.0 14.2 2.5 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TMEM135_C_rich PF15982.5 CDO68204.1 - 0.052 14.1 0.1 0.13 12.9 0.1 1.6 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 WD40 PF00400.32 CDO68205.1 - 1.8e-39 133.0 4.3 2.1e-07 31.5 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO68205.1 - 1.5e-14 54.0 0.0 0.042 14.1 0.0 6.1 4 2 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 CDO68205.1 - 3.3e-13 48.9 2.4 3.3e-13 48.9 2.4 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 CDO68205.1 - 0.0005 19.1 0.0 2.6 6.9 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CDO68205.1 - 0.0033 16.8 0.0 0.74 9.1 0.0 3.3 3 1 1 4 4 4 1 WD40-like domain Nbas_N PF15492.6 CDO68205.1 - 0.033 13.5 0.0 14 4.9 0.0 3.2 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CDO68205.1 - 0.045 12.4 1.4 8 5.0 0.0 3.6 4 1 1 5 5 5 0 Nucleoporin Nup120/160 F-box-like PF12937.7 CDO68206.1 - 0.021 14.7 0.3 0.057 13.3 0.3 1.8 1 0 0 1 1 1 0 F-box-like Ank_4 PF13637.6 CDO68207.1 - 1.7e-12 47.6 1.0 1.7e-06 28.5 0.2 4.5 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDO68207.1 - 1.7e-10 41.3 2.0 0.00012 22.6 0.2 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDO68207.1 - 3.9e-09 36.0 2.4 0.076 13.6 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CDO68207.1 - 6.4e-08 32.7 4.8 0.0096 16.2 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CDO68207.1 - 4.6e-06 26.8 8.2 0.0086 16.5 0.3 3.7 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 CDO68207.1 - 0.00016 21.5 0.1 0.0043 16.9 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain MAD PF05557.13 CDO68207.1 - 0.0045 15.4 0.7 0.0066 14.9 0.7 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Filament PF00038.21 CDO68207.1 - 0.03 13.9 1.6 0.05 13.2 1.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein Exonuc_VII_L PF02601.15 CDO68207.1 - 0.067 12.7 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.11 CDO68207.1 - 0.15 11.6 0.9 0.26 10.9 0.9 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ATG16 PF08614.11 CDO68207.1 - 0.25 11.5 5.4 0.68 10.1 5.4 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) OmpH PF03938.14 CDO68207.1 - 2 8.8 6.6 3.6 7.9 6.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1043 PF06295.12 CDO68207.1 - 5.1 7.1 6.4 1.3 9.0 2.4 2.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1043) DUF3450 PF11932.8 CDO68207.1 - 6.9 5.9 9.2 8 5.7 6.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PX PF00787.24 CDO68208.1 - 3.2e-15 56.1 0.0 5.6e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 PX domain Retrotran_gag_2 PF14223.6 CDO68210.1 - 5.9e-23 81.1 0.0 7.6e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Med15 PF09606.10 CDO68210.1 - 0.25 10.0 2.0 0.31 9.7 2.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sacchrp_dh_C PF16653.5 CDO68211.1 - 4.4e-85 286.0 0.0 1.1e-84 284.6 0.0 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 CDO68211.1 - 6.2e-71 237.7 0.0 1.2e-70 236.8 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CDO68211.1 - 4e-24 84.2 0.1 8.9e-24 83.1 0.1 1.6 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Sacchrp_dh_NADP PF03435.18 CDO68211.1 - 6.2e-23 81.5 2.2 2e-22 79.8 0.3 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CDO68211.1 - 1.6e-06 28.2 0.1 2.4e-05 24.4 0.1 2.6 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 CDO68211.1 - 2.3e-05 25.0 0.0 0.00016 22.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO68211.1 - 0.00054 20.7 0.1 0.0041 17.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO68211.1 - 0.0061 17.2 0.0 0.9 10.2 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain F420_oxidored PF03807.17 CDO68211.1 - 0.055 14.1 0.1 0.15 12.7 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 CDO68211.1 - 0.082 12.8 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H-binding Methyltransf_18 PF12847.7 CDO68211.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CDO68211.1 - 0.17 11.5 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 CDO68211.1 - 0.18 10.9 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Hydrophobin PF01185.18 CDO68212.1 - 2.8e-23 82.3 10.6 3.5e-23 82.0 10.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Torus PF16131.5 CDO68213.1 - 0.16 12.7 0.1 0.37 11.5 0.1 1.5 1 0 0 1 1 1 0 Torus domain Hydrophobin PF01185.18 CDO68215.1 - 9.4e-23 80.7 8.0 1.2e-22 80.4 8.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Transposase_21 PF02992.14 CDO68218.1 - 1.7e-05 24.2 0.1 5.1e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 G-alpha PF00503.20 CDO68221.1 - 3.3e-94 316.0 0.0 4.1e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDO68221.1 - 7.6e-13 48.3 0.0 2.9e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDO68221.1 - 0.03 13.8 0.1 0.7 9.4 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 CDO68221.1 - 0.034 14.4 0.0 4.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GMC_oxred_C PF05199.13 CDO68223.1 - 4.3e-09 37.0 0.1 1.4e-08 35.4 0.1 1.9 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CDO68223.1 - 0.0099 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 CDO68223.1 - 0.022 14.0 0.1 5.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDO68223.1 - 0.12 11.6 0.2 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain UreE_C PF05194.12 CDO68223.1 - 0.22 12.0 7.0 0.58 10.7 7.0 1.7 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain SelP_N PF04592.14 CDO68223.1 - 1 8.7 3.7 1.8 7.9 3.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region AUDH_Cupin PF18637.1 CDO68224.1 - 1.5e-60 203.8 0.5 2.5e-60 203.1 0.5 1.4 1 0 0 1 1 1 1 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain PBP3 PF18056.1 CDO68224.1 - 4.3e-27 94.4 0.1 9.2e-27 93.3 0.1 1.6 2 0 0 2 2 2 1 Penicillin Binding Protein 3 Domain VCBS PF13517.6 CDO68224.1 - 5.9e-05 23.6 8.7 0.00036 21.0 0.1 4.5 4 0 0 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CDO68224.1 - 0.014 15.5 0.0 0.078 13.1 0.0 2.4 1 0 0 1 1 1 0 FG-GAP repeat GMC_oxred_C PF05199.13 CDO68225.1 - 1.2e-06 29.1 0.2 8.9e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CDO68225.1 - 1.6e-06 27.7 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_3 PF01494.19 CDO68225.1 - 0.025 13.8 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DUF659 PF04937.15 CDO68226.1 - 2.3e-08 34.0 0.0 4.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CDO68226.1 - 3e-05 23.7 0.0 6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pho88 PF10032.9 CDO68227.1 - 1.1e-27 96.5 2.7 1.1e-27 96.4 2.7 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DDE_1 PF03184.19 CDO68229.1 - 2.8e-15 56.4 0.0 5.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CDO68229.1 - 1.4e-06 28.2 0.2 3.1e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Bot1p PF12298.8 CDO68229.1 - 0.07 13.3 0.4 0.07 13.3 0.4 2.3 2 1 1 3 3 3 0 Eukaryotic mitochondrial regulator protein zf-CCCH PF00642.24 CDO68230.1 - 3.4e-15 55.5 14.7 2.5e-06 27.2 0.3 4.1 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDO68230.1 - 5.4e-11 43.2 15.4 7.2e-05 23.5 0.1 4.1 2 1 2 4 4 4 3 Torus domain zf-CCCH_4 PF18044.1 CDO68230.1 - 1e-06 28.4 24.8 0.00038 20.2 2.6 4.8 5 0 0 5 5 5 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDO68230.1 - 3.8e-06 26.7 30.3 3.8e-05 23.6 1.6 5.6 6 1 0 6 6 6 3 Zinc finger domain zf-CCCH_2 PF14608.6 CDO68230.1 - 1.6e-05 25.2 28.7 0.01 16.3 5.0 4.2 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger TPD52 PF04201.15 CDO68231.1 - 0.044 13.4 0.3 0.46 10.1 0.0 2.6 2 0 0 2 2 2 0 Tumour protein D52 family Bd3614_N PF14442.6 CDO68233.1 - 0.063 13.6 1.3 0.16 12.3 1.3 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal HTH_10 PF04967.12 CDO68233.1 - 0.098 12.5 0.0 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 HTH DNA binding domain Pro_CA PF00484.19 CDO68234.1 - 0.037 14.3 0.0 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Carbonic anhydrase PI_PP_I PF18363.1 CDO68235.1 - 0.00035 20.7 0.1 0.0045 17.1 0.0 2.3 2 1 0 2 2 2 1 Phosphoinositide phosphatase insertion domain DUF1664 PF07889.12 CDO68235.1 - 0.00083 19.4 0.2 0.036 14.1 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Spc7 PF08317.11 CDO68235.1 - 0.0028 16.6 2.0 0.0028 16.6 0.7 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein MIP-T3_C PF17749.1 CDO68235.1 - 0.0049 16.8 1.8 0.015 15.3 0.4 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Leu_zip PF15294.6 CDO68235.1 - 0.0097 15.5 2.0 0.013 15.0 1.6 1.4 2 0 0 2 2 2 1 Leucine zipper IFT57 PF10498.9 CDO68235.1 - 0.019 13.9 1.0 0.019 13.9 1.0 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 VPS11_C PF12451.8 CDO68235.1 - 0.058 13.6 11.0 1.6 9.0 0.0 3.6 3 1 1 4 4 4 0 Vacuolar protein sorting protein 11 C terminal UPF0242 PF06785.11 CDO68235.1 - 0.13 12.4 3.6 0.052 13.7 1.1 1.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4164 PF13747.6 CDO68235.1 - 0.56 10.5 4.8 0.22 11.8 1.5 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Chromo PF00385.24 CDO68236.1 - 4.4e-08 32.9 0.0 6.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Exo_endo_phos_2 PF14529.6 CDO68238.1 - 5e-06 26.3 0.2 9.9e-06 25.4 0.2 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDO68238.1 - 0.00021 20.9 1.5 0.00046 19.8 1.5 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thiamine_BP PF01910.17 CDO68238.1 - 0.033 14.1 0.1 0.081 12.9 0.1 1.6 1 0 0 1 1 1 0 Thiamine-binding protein Prenyltrans PF00432.21 CDO68238.1 - 0.042 13.6 1.3 0.11 12.3 1.3 1.8 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat zf-CCHC PF00098.23 CDO68238.1 - 0.36 11.0 4.7 2.3 8.4 1.9 2.7 2 0 0 2 2 2 0 Zinc knuckle MscS_porin PF12795.7 CDO68238.1 - 0.53 9.8 3.1 0.97 8.9 3.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain RL10P_insert PF17777.1 CDO68241.1 - 9.4e-23 80.0 0.0 1.6e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CDO68241.1 - 1.1e-22 80.0 0.0 1.6e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DinI PF06183.13 CDO68241.1 - 0.086 13.2 0.3 0.16 12.3 0.3 1.5 1 0 0 1 1 1 0 DinI-like family HEAT_2 PF13646.6 CDO68242.1 - 3.5e-32 110.6 1.8 1.3e-14 54.3 0.1 4.2 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 CDO68242.1 - 3.7e-24 82.9 1.4 0.0007 20.0 0.1 7.3 8 0 0 8 8 8 4 PBS lyase HEAT-like repeat HEAT PF02985.22 CDO68242.1 - 5.5e-11 41.8 1.7 0.046 14.0 0.0 5.2 6 0 0 6 6 6 3 HEAT repeat Arm PF00514.23 CDO68242.1 - 2.7e-05 24.0 0.1 0.11 12.6 0.1 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CDO68242.1 - 5.9e-05 23.5 2.2 0.58 10.7 0.4 4.2 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 CDO68242.1 - 0.0042 17.2 0.0 1.9 8.5 0.0 3.4 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 zf-CCCH_6 PF18585.1 CDO68242.1 - 0.082 12.8 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Plavaka PF18759.1 CDO68243.1 - 8.1e-26 91.0 0.1 7.6e-25 87.8 0.1 2.2 1 1 0 1 1 1 1 Plavaka transposase Adaptin_binding PF10199.9 CDO68244.1 - 7.8e-11 42.6 0.5 1.8e-09 38.2 0.5 2.3 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Terpene_synth_C PF03936.16 CDO68244.1 - 0.069 12.5 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain TMEM154 PF15102.6 CDO68244.1 - 1.7 8.5 3.9 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family APG6_N PF17675.1 CDO68246.1 - 0.056 14.0 1.2 0.093 13.3 1.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Sporozoite_P67 PF05642.11 CDO68247.1 - 2 6.4 7.8 2.4 6.2 7.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Methyltransf_25 PF13649.6 CDO68248.1 - 3.7e-12 46.8 0.0 3.3e-11 43.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO68248.1 - 9e-07 28.8 0.0 2.4e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO68248.1 - 1.7e-06 28.0 0.0 3.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO68248.1 - 3.1e-05 24.6 0.0 8.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO68248.1 - 0.0043 17.8 0.0 0.012 16.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CDO68248.1 - 0.025 14.7 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 CDO68248.1 - 0.042 13.3 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CDC37_N PF03234.14 CDO68249.1 - 2.8e-43 147.9 1.5 2.8e-43 147.9 1.5 2.7 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 CDO68249.1 - 1.8e-30 105.3 0.0 3.5e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 CDO68249.1 - 4.7e-22 78.0 1.8 4.7e-22 78.0 1.8 2.4 2 0 0 2 2 2 1 Cdc37 C terminal domain DPBB_1 PF03330.18 CDO68250.1 - 8.5e-08 32.4 0.1 1.8e-07 31.4 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CDO68250.1 - 0.011 15.6 0.2 0.018 14.9 0.1 1.4 1 1 0 1 1 1 0 Barwin family FANCL_C PF11793.8 CDO68250.1 - 0.13 12.4 0.8 6.7 7.0 0.0 2.7 1 1 2 3 3 3 0 FANCL C-terminal domain zf-ribbon_3 PF13248.6 CDO68250.1 - 0.17 11.3 0.4 0.17 11.3 0.4 2.2 3 0 0 3 3 3 0 zinc-ribbon domain His_Phos_1 PF00300.22 CDO68251.1 - 6e-16 58.7 0.4 4.8e-15 55.8 0.4 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4448 PF14610.6 CDO68253.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) CtnDOT_TraJ PF07863.11 CDO68253.1 - 6.6 7.5 13.7 0.4 11.4 3.0 3.0 1 1 2 3 3 3 0 Homologues of TraJ from Bacteroides conjugative transposon GPI-anchored PF10342.9 CDO68254.1 - 0.00025 21.7 0.0 0.00057 20.6 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GST_C PF00043.25 CDO68256.1 - 7.1e-11 42.2 0.0 1.6e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO68256.1 - 1.1e-10 41.7 0.0 4.5e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CDO68256.1 - 4.6e-10 39.8 0.0 1.2e-09 38.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO68256.1 - 2.6e-08 34.1 0.0 5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO68256.1 - 1.9e-07 31.0 0.1 4.8e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO68256.1 - 2.9e-07 30.6 0.0 5.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MRP-L20 PF12824.7 CDO68258.1 - 5.7e-25 88.4 9.0 2.7e-24 86.2 9.0 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 CDO68258.1 - 0.0013 19.3 0.1 0.0013 19.3 0.1 2.4 3 0 0 3 3 3 1 Homeodomain-like domain Sas10 PF09368.10 CDO68259.1 - 4.9e-26 91.0 7.6 4.9e-26 91.0 7.6 4.3 4 1 1 5 5 5 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CDO68259.1 - 2.1e-05 25.1 0.9 2.1e-05 25.1 0.9 2.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family FUSC PF04632.12 CDO68259.1 - 1.2 7.5 4.4 2 6.8 4.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Zn_clus PF00172.18 CDO68260.1 - 2.7e-06 27.4 5.6 4.9e-06 26.6 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CDO68260.1 - 0.0027 16.8 0.0 0.026 13.5 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tom22 PF04281.13 CDO68261.1 - 8.6e-39 132.5 0.4 9.9e-39 132.3 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 NAD_binding_10 PF13460.6 CDO68262.1 - 6.3e-13 49.0 0.0 8.9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CDO68262.1 - 1.2e-12 47.9 0.0 1.6e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CDO68262.1 - 9.5e-11 41.6 0.4 1.5e-09 37.7 0.4 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO68262.1 - 6.1e-10 38.6 0.1 4.3e-09 35.8 0.1 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDO68262.1 - 1e-09 37.9 0.0 2.6e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CDO68262.1 - 4.1e-06 26.2 0.1 0.044 13.0 0.0 3.1 1 1 1 3 3 3 2 Male sterility protein adh_short PF00106.25 CDO68262.1 - 0.0018 17.8 0.1 0.019 14.4 0.1 2.2 1 1 1 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 CDO68262.1 - 0.0054 16.2 0.0 0.0094 15.4 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 CDO68262.1 - 0.015 14.9 0.0 0.037 13.6 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 CDO68262.1 - 0.086 11.9 0.1 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 CDO68262.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2462 PF09495.10 CDO68263.1 - 1.1e-21 77.3 12.1 1.1e-21 77.3 12.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) HTH_Tnp_Tc5 PF03221.16 CDO68264.1 - 5.4e-13 48.8 0.0 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 CDO68264.1 - 0.00053 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_4 PF13613.6 CDO68264.1 - 0.00063 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_IclR PF09339.10 CDO68264.1 - 0.0016 18.2 0.0 0.074 12.9 0.0 2.7 3 0 0 3 3 3 1 IclR helix-turn-helix domain CENP-B_N PF04218.13 CDO68264.1 - 0.0028 17.2 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Crp_2 PF13545.6 CDO68264.1 - 0.0041 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 CDO68264.1 - 0.0043 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 CDO68264.1 - 0.0055 16.6 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_37 PF13744.6 CDO68264.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 CDO68264.1 - 0.02 15.2 0.0 0.057 13.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 CDO68264.1 - 0.036 13.8 0.1 0.067 13.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 CDO68264.1 - 0.045 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding LacI PF00356.21 CDO68264.1 - 0.063 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_36 PF13730.6 CDO68264.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 CDO68264.1 - 0.18 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 CAF1 PF04857.20 CDO68265.1 - 3.6e-12 46.1 0.1 1.6e-07 30.8 0.1 2.8 1 1 1 2 2 2 2 CAF1 family ribonuclease SH3_9 PF14604.6 CDO68266.1 - 7.5e-21 73.7 1.6 7.6e-10 38.5 0.3 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CDO68266.1 - 1.6e-18 66.1 0.2 2.5e-08 33.5 0.3 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CDO68266.1 - 5.4e-16 57.9 1.0 1.5e-07 30.9 0.0 2.7 2 1 0 2 2 2 2 SH3 domain FCH PF00611.23 CDO68266.1 - 4e-11 43.0 0.6 4e-11 43.0 0.6 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.11 CDO68266.1 - 0.0075 16.5 0.1 0.015 15.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain DPBB_1 PF03330.18 CDO68267.1 - 4.4e-06 26.9 0.1 1.4e-05 25.3 0.1 1.9 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CDO68267.1 - 0.04 13.8 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Barwin family Mannitol_dh_C PF08125.13 CDO68268.1 - 5.1e-53 180.1 0.1 2.7e-52 177.7 0.0 2.0 2 1 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 CDO68268.1 - 2.1e-25 89.7 0.0 3.6e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 CDO68268.1 - 0.013 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cullin PF00888.22 CDO68271.1 - 1.1e-191 638.6 16.9 1.6e-191 638.1 16.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDO68271.1 - 2.2e-27 94.9 3.4 7.6e-27 93.1 3.4 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF1727 PF08353.10 CDO68271.1 - 0.055 13.4 0.1 0.23 11.4 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) Rrf2 PF02082.20 CDO68271.1 - 0.058 13.7 0.3 0.35 11.2 0.1 2.4 3 0 0 3 3 3 0 Transcriptional regulator Penicillinase_R PF03965.16 CDO68271.1 - 0.12 12.7 6.2 1.4 9.3 0.1 3.9 4 0 0 4 4 4 0 Penicillinase repressor Phage_rep_O PF04492.13 CDO68271.1 - 0.24 12.0 2.0 0.39 11.3 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage replication protein O NCE101 PF11654.8 CDO68272.1 - 0.24 11.1 2.6 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 Non-classical export protein 1 DUF308 PF03729.13 CDO68272.1 - 7.1 7.0 17.7 0.24 11.7 3.2 3.2 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) HAT_KAT11 PF08214.11 CDO68273.1 - 1e-40 140.1 0.0 1.4e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Totivirus_coat PF05518.11 CDO68273.1 - 1.2 7.0 5.5 1.9 6.5 5.5 1.2 1 0 0 1 1 1 0 Totivirus coat protein DUF659 PF04937.15 CDO68274.1 - 1.3e-13 51.1 0.1 2.2e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) K_oxygenase PF13434.6 CDO68275.1 - 3.3e-48 164.6 0.0 4.4e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CDO68275.1 - 0.00012 21.5 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDO68275.1 - 0.00096 18.8 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDO68275.1 - 0.041 13.0 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain gp12-short_mid PF09089.10 CDO68275.1 - 0.065 13.4 0.1 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Phage short tail fibre protein gp12, middle domain Mqo PF06039.15 CDO68275.1 - 0.072 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 CDO68275.1 - 0.082 13.5 0.0 2.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L24e PF01246.20 CDO68277.1 - 3e-32 110.6 6.3 3e-32 110.6 6.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 CDO68277.1 - 0.0061 16.5 4.0 0.011 15.6 4.0 1.4 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif HAGH_C PF16123.5 CDO68277.1 - 0.025 15.1 1.1 0.025 15.1 1.1 1.9 1 1 2 3 3 3 0 Hydroxyacylglutathione hydrolase C-terminus zf-FLZ PF04570.14 CDO68277.1 - 0.17 11.3 2.1 0.42 10.1 2.1 1.6 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2116 PF09889.9 CDO68277.1 - 0.35 10.9 3.3 0.38 10.8 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ATG_C PF09333.11 CDO68278.1 - 6.6e-39 132.2 0.2 1.7e-38 130.9 0.2 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 CDO68278.1 - 1.5e-12 47.7 0.0 3.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 CDO68278.1 - 2.9e-12 46.6 0.0 1.9e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 CDO68278.1 - 8.2e-05 22.5 0.8 0.00032 20.5 0.0 2.4 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal Apt1 PF10351.9 CDO68278.1 - 0.053 12.4 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain NatB_MDM20 PF09797.9 CDO68279.1 - 1.6e-74 251.1 0.3 1.6e-74 251.1 0.3 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit RPA_C PF08784.11 CDO68279.1 - 1.8e-10 41.4 0.0 4.5e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal TPR_19 PF14559.6 CDO68279.1 - 1.3e-08 35.2 6.6 0.0096 16.4 1.2 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDO68279.1 - 6.7e-06 26.5 1.3 0.81 10.7 0.0 6.7 4 1 3 7 7 7 1 Tetratricopeptide repeat tRNA_anti-codon PF01336.25 CDO68279.1 - 0.00019 21.3 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TPR_16 PF13432.6 CDO68279.1 - 0.0016 19.1 0.6 15 6.3 0.4 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDO68279.1 - 0.028 14.2 0.3 45 4.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 CDO68279.1 - 0.062 13.7 2.4 0.14 12.6 0.3 2.7 2 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_15 PF13429.6 CDO68279.1 - 0.072 12.3 4.8 0.42 9.8 1.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat RMI2 PF16100.5 CDO68279.1 - 0.14 12.0 0.2 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 ANAPC3 PF12895.7 CDO68279.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 CDO68279.1 - 0.85 9.0 3.4 0.71 9.2 0.3 2.4 2 1 1 3 3 3 0 Coatomer epsilon subunit NCE101 PF11654.8 CDO68280.1 - 5.6e-20 70.8 0.6 9e-20 70.1 0.6 1.3 1 0 0 1 1 1 1 Non-classical export protein 1 Ribosomal_L30_N PF08079.12 CDO68281.1 - 2e-28 98.4 16.6 2e-28 98.4 16.6 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CDO68281.1 - 2.6e-18 65.7 2.6 2.6e-18 65.7 2.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Tipalpha PF16753.5 CDO68281.1 - 0.12 12.2 1.1 0.88 9.4 0.1 2.3 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter LRR_6 PF13516.6 CDO68282.1 - 0.094 12.8 0.0 3.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeat CLTH PF10607.9 CDO68283.1 - 3.3e-09 36.8 0.0 5.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CDO68283.1 - 0.00075 19.4 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 LisH PQ-loop PF04193.14 CDO68284.1 - 1.6e-38 130.3 8.8 4.6e-19 67.9 0.2 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 CDO68284.1 - 0.028 14.4 0.3 0.087 12.9 0.3 1.7 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange AAA_12 PF13087.6 CDO68285.1 - 1.1e-47 162.3 0.0 1.8e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDO68285.1 - 6.4e-42 144.1 0.6 5.7e-37 127.9 0.2 2.5 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CDO68285.1 - 0.00062 19.6 0.0 0.047 13.4 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CDO68285.1 - 0.0012 18.6 0.2 0.09 12.5 0.3 2.4 2 0 0 2 2 2 1 AAA domain ICMT PF04140.14 CDO68286.1 - 1.9e-16 60.3 0.4 8.2e-14 51.8 0.1 2.5 1 1 1 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO68286.1 - 2.3e-09 37.6 2.2 7.6e-09 35.9 0.2 2.4 2 1 1 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO68286.1 - 5.2e-08 32.1 0.1 7.1e-08 31.6 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 CDO68287.1 - 5.6e-14 52.3 0.1 1.5e-12 47.8 0.0 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO68287.1 - 4.9e-09 36.5 0.4 2.8e-08 34.1 0.2 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO68287.1 - 0.00011 21.2 0.0 0.00048 19.0 0.0 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family GYF PF02213.16 CDO68288.1 - 4.5e-07 29.4 0.8 9.3e-07 28.4 0.8 1.6 1 0 0 1 1 1 1 GYF domain SNF2_N PF00176.23 CDO68289.1 - 5.1e-48 163.6 0.2 5.6e-31 107.5 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Rad54_N PF08658.10 CDO68289.1 - 3.1e-46 157.8 8.6 5.8e-46 156.9 8.6 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 CDO68289.1 - 6.9e-18 65.0 0.0 2.2e-17 63.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CDO68289.1 - 2.2e-07 30.4 1.1 5.4e-07 29.1 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 CDO68289.1 - 4.1e-06 26.2 0.0 8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CDO68289.1 - 0.00048 20.2 0.0 0.19 11.7 0.0 2.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDO68289.1 - 0.005 17.1 0.0 0.04 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain U1snRNP70_N PF12220.8 CDO68289.1 - 0.011 16.4 3.5 0.012 16.3 0.2 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4598 PF15370.6 CDO68289.1 - 9.2 6.8 8.2 22 5.5 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) Chromo PF00385.24 CDO68290.1 - 3.1e-09 36.6 0.7 5.5e-09 35.8 0.7 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor_3 PF18115.1 CDO68291.1 - 4.1e-14 52.1 0.0 8.2e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 CDO68291.1 - 5.1e-09 36.2 0.3 1.4e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) BRCT PF00533.26 CDO68291.1 - 6.8e-06 26.4 0.1 0.00046 20.5 0.0 2.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain 53-BP1_Tudor PF09038.10 CDO68291.1 - 1.4e-05 25.0 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor TUDOR_5 PF18359.1 CDO68291.1 - 0.00019 21.0 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 BRCT_2 PF16589.5 CDO68291.1 - 0.0043 17.4 0.0 1.6 9.2 0.0 2.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DUF1325 PF07039.11 CDO68291.1 - 0.025 14.7 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 SGF29 tudor-like domain BRCT_3 PF18428.1 CDO68291.1 - 0.028 14.5 0.1 8.5 6.5 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDO68291.1 - 0.16 11.9 0.0 19 5.3 0.0 2.5 2 0 0 2 2 2 0 twin BRCT domain DUF4536 PF15055.6 CDO68292.1 - 0.043 14.1 0.0 0.77 10.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) TMEM51 PF15345.6 CDO68292.1 - 0.054 13.3 2.2 0.38 10.6 0.0 2.6 3 0 0 3 3 3 0 Transmembrane protein 51 LapA_dom PF06305.11 CDO68292.1 - 0.17 11.7 0.2 0.45 10.4 0.2 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Snf7 PF03357.21 CDO68293.1 - 9e-18 64.5 11.4 1.4e-17 63.8 11.4 1.2 1 0 0 1 1 1 1 Snf7 AKNA PF12443.8 CDO68293.1 - 0.016 15.9 2.6 0.042 14.5 0.4 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor Phage_GP20 PF06810.11 CDO68293.1 - 0.33 10.7 9.0 0.7 9.7 0.8 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 CdvA PF18822.1 CDO68293.1 - 1.4 8.7 9.2 6.9 6.5 9.2 2.2 1 1 0 1 1 1 0 CdvA-like coiled-coil domain NPV_P10 PF05531.12 CDO68293.1 - 1.9 9.0 4.6 0.81 10.2 0.5 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 CDO68293.1 - 6 7.1 12.6 1.1 9.5 3.6 2.5 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TruB_N PF01509.18 CDO68295.1 - 5.9e-34 117.6 0.0 2.3e-33 115.7 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Aldo_ket_red PF00248.21 CDO68295.1 - 1.5e-31 109.7 0.0 8.2e-31 107.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TruB_C_2 PF16198.5 CDO68295.1 - 0.0014 18.7 0.1 0.0065 16.6 0.0 2.1 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain DHDPS PF00701.22 CDO68296.1 - 4.4e-27 94.5 0.0 1.9e-26 92.4 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family AlaDh_PNT_N PF05222.15 CDO68297.1 - 3.8e-44 150.3 0.2 4.9e-44 149.9 0.2 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB PF02233.16 CDO68298.1 - 4.2e-169 563.3 25.0 4.2e-169 563.3 25.0 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CDO68298.1 - 1.1e-54 184.9 0.2 3.5e-54 183.3 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain PNTB_4TM PF12769.7 CDO68298.1 - 9.2e-32 109.4 4.4 9.2e-32 109.4 4.4 4.6 2 1 1 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch PRIMA1 PF16101.5 CDO68298.1 - 0.32 11.0 1.3 0.82 9.7 1.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Nuc_sug_transp PF04142.15 CDO68299.1 - 3.4e-98 328.7 17.3 1e-97 327.1 17.3 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 CDO68299.1 - 4.7e-07 29.3 9.3 8.6e-07 28.4 9.3 1.4 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 CDO68299.1 - 9.7e-05 21.5 1.0 9.7e-05 21.5 1.0 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CDO68299.1 - 0.00014 22.1 0.7 0.00014 22.1 0.7 2.6 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 CDO68299.1 - 0.049 13.0 0.2 0.049 13.0 0.2 2.4 3 0 0 3 3 3 0 Triose-phosphate Transporter family Exo_endo_phos PF03372.23 CDO68300.1 - 4.1e-09 36.3 0.0 1.5e-08 34.4 0.1 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family OTU PF02338.19 CDO68300.1 - 0.00016 22.2 0.0 0.00038 21.0 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Tom37 PF10568.9 CDO68301.1 - 3.8e-30 104.8 0.0 6.3e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 CDO68301.1 - 2.1e-10 40.2 0.2 6.1e-10 38.8 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CDO68301.1 - 5.6e-08 33.4 0.0 1.6e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 CDO68301.1 - 0.0021 18.0 0.1 0.005 16.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TAFII55_N PF04658.13 CDO68302.1 - 4.6e-59 198.7 1.9 4.6e-59 198.7 1.9 2.0 2 0 0 2 2 2 1 TAFII55 protein conserved region HEPN_RnaseLS PF18869.1 CDO68302.1 - 0.14 12.3 0.1 0.62 10.2 0.0 1.9 2 0 0 2 2 2 0 RnaseLS-like HEPN Trep_dent_lipo PF09710.10 CDO68302.1 - 0.87 8.5 4.7 1.5 7.7 4.7 1.3 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Glucan_synthase PF02364.15 CDO68303.1 - 0 1319.3 0.0 0 1318.7 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Gaa1 PF04114.14 CDO68303.1 - 2.1e-94 317.3 4.9 2.1e-94 317.3 4.9 3.9 4 1 0 4 4 4 1 Gaa1-like, GPI transamidase component FKS1_dom1 PF14288.6 CDO68303.1 - 1.4e-42 145.1 0.0 3.6e-42 143.7 0.0 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SpoIIE PF07228.12 CDO68304.1 - 5e-13 49.4 0.0 1.1e-12 48.2 0.0 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CDO68304.1 - 0.00018 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CDO68304.1 - 0.0068 16.1 0.0 0.034 13.8 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C DNA_pol3_gamma3 PF12169.8 CDO68304.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III Ras PF00071.22 CDO68305.1 - 3.8e-50 169.6 0.0 4.5e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO68305.1 - 2.9e-30 105.0 0.0 5e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO68305.1 - 5e-10 39.1 0.0 6.9e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDO68305.1 - 0.00048 19.6 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDO68305.1 - 0.0014 18.7 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CDO68305.1 - 0.0014 17.8 1.1 0.73 8.9 0.2 2.5 2 1 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 CDO68305.1 - 0.0094 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CDO68305.1 - 0.017 15.5 0.1 0.15 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 CDO68305.1 - 0.022 14.2 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 CDO68305.1 - 0.041 13.6 0.3 0.069 12.9 0.2 1.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CDO68305.1 - 0.083 12.8 0.1 8.1 6.3 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 CDO68305.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 CDO68305.1 - 0.11 12.9 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 CDO68305.1 - 0.13 12.5 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain STAS PF01740.21 CDO68305.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 STAS domain MFS_1 PF07690.16 CDO68306.1 - 8.9e-46 156.4 43.4 1.5e-45 155.7 41.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO68306.1 - 4.2e-16 58.5 17.1 7.4e-16 57.7 17.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CDO68306.1 - 9.8e-12 44.5 13.4 9.8e-12 44.5 13.4 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3522 PF12036.8 CDO68306.1 - 0.02 15.2 0.3 0.02 15.2 0.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3522) Neurensin PF14927.6 CDO68306.1 - 0.11 12.3 0.2 0.73 9.5 0.2 2.4 2 0 0 2 2 2 0 Neurensin HlyIII PF03006.20 CDO68306.1 - 0.48 10.1 12.9 4.6 6.9 12.5 2.7 1 1 0 1 1 1 0 Haemolysin-III related Vac_ImportDeg PF09783.9 CDO68307.1 - 4e-43 147.0 0.0 5e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Pkinase PF00069.25 CDO68308.1 - 8.8e-28 97.4 0.0 1e-27 97.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO68308.1 - 1.1e-13 51.1 0.0 1.4e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO68308.1 - 2.3e-08 33.2 0.0 2.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO68308.1 - 0.013 15.4 0.0 6.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Not3 PF04065.15 CDO68309.1 - 0.0049 16.3 3.9 0.011 15.1 3.9 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Mt_ATP-synt_D PF05873.12 CDO68309.1 - 0.012 15.5 1.4 0.024 14.5 1.4 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Phage_GP20 PF06810.11 CDO68309.1 - 0.017 15.0 3.2 0.031 14.1 3.2 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 GrpE PF01025.19 CDO68309.1 - 0.43 10.2 6.3 0.93 9.1 6.3 1.5 1 0 0 1 1 1 0 GrpE Fib_alpha PF08702.10 CDO68309.1 - 0.93 9.7 5.4 2 8.6 5.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FapA PF03961.13 CDO68309.1 - 1.5 7.4 4.4 2.2 6.8 4.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CCDC-167 PF15188.6 CDO68309.1 - 3.2 8.1 6.8 1.2 9.5 3.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 OmpH PF03938.14 CDO68309.1 - 4 7.8 9.0 9 6.6 9.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) JmjC PF02373.22 CDO68310.1 - 1.3e-08 35.2 0.1 6.4e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase C1_2 PF03107.16 CDO68310.1 - 0.00095 19.4 0.6 0.0023 18.2 0.6 1.6 1 0 0 1 1 1 1 C1 domain DTW PF03942.15 CDO68310.1 - 0.017 14.8 1.1 3.5 7.3 0.7 2.3 2 0 0 2 2 2 0 DTW domain DUF1465 PF07323.12 CDO68310.1 - 0.033 14.0 0.2 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) AraC_binding PF02311.19 CDO68310.1 - 0.12 12.2 0.0 0.78 9.6 0.0 2.1 2 0 0 2 2 2 0 AraC-like ligand binding domain zf-C5HC2 PF02928.16 CDO68310.1 - 4.1 7.9 9.1 0.43 11.0 3.8 2.2 2 0 0 2 2 2 0 C5HC2 zinc finger LEA_2 PF03168.13 CDO68311.1 - 8e-07 29.5 0.1 1.6e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.12 CDO68311.1 - 0.00022 20.6 0.2 0.00035 19.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Vac7 PF12751.7 CDO68311.1 - 0.022 14.2 0.7 0.11 11.9 0.7 1.9 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 DUF726 PF05277.12 CDO68312.1 - 3.2e-41 141.4 0.0 4.1e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_8 PF06259.12 CDO68312.1 - 0.0029 17.2 0.1 0.0056 16.3 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase Cutinase PF01083.22 CDO68312.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 1 1 2 2 2 0 Cutinase Abhydrolase_6 PF12697.7 CDO68312.1 - 0.098 13.2 0.0 0.1 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDO68312.1 - 0.19 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF726 PF05277.12 CDO68313.1 - 2.6e-36 125.3 4.8 3.9e-36 124.7 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Spore_III_AB PF09548.10 CDO68313.1 - 0.011 15.8 0.4 0.092 12.8 0.1 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Barstar PF01337.18 CDO68313.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Peptidase_M41 PF01434.18 CDO68314.1 - 2.9e-53 180.5 0.5 2.9e-28 99.0 0.0 2.5 2 0 0 2 2 2 2 Peptidase family M41 AAA PF00004.29 CDO68314.1 - 4.6e-37 127.4 0.0 1.2e-36 126.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDO68314.1 - 6.8e-10 38.6 0.1 1.7e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDO68314.1 - 6.2e-05 23.4 4.6 0.0013 19.2 0.2 3.3 3 1 1 4 4 3 1 AAA ATPase domain RuvB_N PF05496.12 CDO68314.1 - 0.00014 21.7 0.1 0.00043 20.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CDO68314.1 - 0.00019 20.8 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CDO68314.1 - 0.00036 20.5 0.1 0.0015 18.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDO68314.1 - 0.00054 20.2 1.0 0.0045 17.3 0.2 2.7 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.14 CDO68314.1 - 0.0035 17.5 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CDO68314.1 - 0.0043 17.2 0.0 0.0096 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDO68314.1 - 0.0052 16.2 0.2 0.012 14.9 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CDO68314.1 - 0.0076 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CDO68314.1 - 0.0092 16.5 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CDO68314.1 - 0.014 15.0 2.8 0.38 10.3 0.4 2.8 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.6 CDO68314.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CDO68314.1 - 0.037 14.0 0.1 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 CDO68314.1 - 0.044 12.9 0.0 0.098 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 CDO68314.1 - 0.068 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PAP1 PF08601.10 CDO68314.1 - 0.075 12.7 6.5 0.13 11.9 6.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 AAA_17 PF13207.6 CDO68314.1 - 0.098 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain T7SS_ESX_EspC PF10824.8 CDO68314.1 - 0.2 12.2 7.2 0.84 10.1 7.2 2.1 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm AAA_7 PF12775.7 CDO68314.1 - 0.6 9.6 4.1 0.43 10.1 0.2 2.5 2 1 0 2 2 2 0 P-loop containing dynein motor region DEAD_2 PF06733.15 CDO68315.1 - 2.3e-47 160.9 0.0 4.3e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 CDO68315.1 - 1.5e-45 155.2 2.1 5.2e-40 137.2 0.3 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 CDO68315.1 - 3.7e-38 131.4 0.4 1.8e-37 129.1 0.0 2.3 3 0 0 3 3 3 1 Helicase C-terminal domain ResIII PF04851.15 CDO68315.1 - 5.7e-05 23.2 0.7 0.0057 16.7 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDO68315.1 - 0.0023 17.7 0.1 0.3 10.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CDO68315.1 - 0.026 13.8 0.5 3.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 CDO68315.1 - 0.18 12.2 0.1 4.5 7.7 0.1 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TPR_12 PF13424.6 CDO68316.1 - 4.7e-06 26.8 8.5 0.022 15.0 0.6 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDO68316.1 - 0.0014 18.4 1.1 2.7 8.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDO68316.1 - 0.0026 17.7 3.4 1.6 9.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.9 CDO68316.1 - 0.0037 17.0 0.0 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_8 PF13181.6 CDO68316.1 - 0.083 13.2 2.4 99 3.5 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDO68316.1 - 0.097 12.7 0.0 42 4.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDO68316.1 - 0.11 12.3 4.1 1.7 8.6 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Shikimate_dh_N PF08501.11 CDO68318.1 - 0.13 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate dehydrogenase substrate binding domain LUC7 PF03194.15 CDO68319.1 - 6.9e-70 235.6 4.6 8.6e-70 235.3 4.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF3418 PF11898.8 CDO68319.1 - 0.084 11.5 0.5 0.11 11.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) tRNA-synt_2 PF00152.20 CDO68321.1 - 2e-74 250.5 0.0 1.1e-40 139.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDO68321.1 - 4.8e-10 39.3 0.0 7.1e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DnaJ PF00226.31 CDO68322.1 - 3.2e-17 62.4 0.1 1.1e-16 60.7 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain Ank_2 PF12796.7 CDO68322.1 - 3.3e-11 43.6 0.1 5.9e-06 26.8 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDO68322.1 - 1.2e-06 29.0 0.0 3.6e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDO68322.1 - 6.4e-06 26.1 0.0 0.00088 19.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CDO68322.1 - 9.9e-06 25.7 0.0 2.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CDO68322.1 - 0.0084 16.5 0.2 0.045 14.2 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeat TFIIA PF03153.13 CDO68322.1 - 0.32 11.0 23.1 0.94 9.4 5.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Borrelia_P83 PF05262.11 CDO68322.1 - 0.47 8.9 11.9 0.67 8.4 11.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein LMBR1 PF04791.16 CDO68322.1 - 1.1 8.0 1.6 1.6 7.6 1.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein EVC2_like PF12297.8 CDO68322.1 - 1.2 7.8 15.6 2 7.0 15.6 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein BCS1_N PF08740.11 CDO68323.1 - 1.1e-45 155.9 0.2 1.5e-45 155.5 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CDO68323.1 - 2e-18 67.1 0.0 4.4e-18 66.0 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDO68323.1 - 0.00023 21.6 0.0 0.00095 19.6 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CDO68323.1 - 0.0015 18.7 0.0 0.0041 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CDO68323.1 - 0.0024 17.1 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 CDO68323.1 - 0.0075 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CDO68323.1 - 0.0092 16.5 0.0 0.03 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CDO68323.1 - 0.0092 15.6 0.0 0.03 13.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDO68323.1 - 0.023 15.0 0.0 0.11 12.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDO68323.1 - 0.03 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 CDO68323.1 - 0.033 14.1 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 CDO68323.1 - 0.036 14.0 0.0 0.077 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CDO68323.1 - 0.037 14.5 0.0 0.073 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 CDO68323.1 - 0.039 14.3 0.0 0.095 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 CDO68323.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CDO68323.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 CDO68323.1 - 0.13 11.6 0.0 0.6 9.4 0.0 1.9 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.18 CDO68323.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase WBS_methylT PF12589.8 CDO68324.1 - 6.9e-10 39.5 1.7 1.2e-09 38.8 1.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 CDO68324.1 - 8e-10 39.2 0.0 1.9e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO68324.1 - 5.9e-09 36.5 0.0 1.5e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO68324.1 - 4.5e-06 27.3 0.2 1.5e-05 25.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO68324.1 - 4.2e-05 23.4 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO68324.1 - 0.0017 18.2 0.0 0.003 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 CDO68324.1 - 0.0047 17.2 0.0 0.0089 16.4 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase TRAPP PF04051.16 CDO68326.1 - 3.5e-37 127.4 0.0 4.5e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_S13 PF00416.22 CDO68327.1 - 1.6e-20 73.7 0.0 7.8e-11 42.5 0.2 2.0 2 0 0 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 CDO68327.1 - 0.0033 16.2 0.1 0.0085 14.9 0.0 1.6 1 1 1 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) XAP5 PF04921.14 CDO68328.1 - 8e-88 294.5 2.6 8e-88 294.5 2.6 2.7 1 1 1 2 2 2 1 XAP5, circadian clock regulator RuBisCO_small PF00101.20 CDO68328.1 - 0.07 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain DUF1043 PF06295.12 CDO68328.1 - 4.2 7.4 10.1 12 5.9 10.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) ATP-synt_D PF01813.17 CDO68329.1 - 4.9e-73 245.2 2.6 6.3e-73 244.8 2.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Ribosomal_L26 PF16906.5 CDO68330.1 - 6e-38 129.2 5.4 9.1e-38 128.6 5.4 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CDO68330.1 - 4.1e-09 36.1 6.9 5.5e-09 35.7 4.2 2.3 2 0 0 2 2 2 1 KOW motif FRG1 PF06229.12 CDO68331.1 - 3.3e-28 98.7 0.2 6.1e-28 97.8 0.2 1.4 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 CDO68331.1 - 0.0044 17.2 0.0 0.008 16.4 0.0 1.5 1 0 0 1 1 1 1 Fascin domain UCH PF00443.29 CDO68332.1 - 1.2e-27 97.0 2.0 3.2e-27 95.7 2.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDO68332.1 - 8.2e-17 61.8 1.9 1.4e-16 61.0 1.9 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CDO68332.1 - 6.9e-07 29.8 0.0 0.00027 21.5 0.0 2.9 2 0 0 2 2 2 1 DUSP domain ubiquitin PF00240.23 CDO68332.1 - 6.4e-06 25.8 0.1 1.4e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Auto_anti-p27 PF06677.12 CDO68332.1 - 3.9 7.7 4.8 42 4.4 0.1 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2757 PF10955.8 CDO68332.1 - 9 6.6 8.3 0.34 11.2 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) DUF4037 PF13228.6 CDO68334.1 - 0.09 13.6 0.2 0.23 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) HBB PF06777.11 CDO68334.1 - 0.11 12.2 0.3 0.18 11.5 0.3 1.3 1 0 0 1 1 1 0 Helical and beta-bridge domain DUF1515 PF07439.11 CDO68334.1 - 0.17 11.9 1.9 6 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) HIP1_clath_bdg PF16515.5 CDO68334.1 - 3.9 8.1 9.1 6.4 7.4 3.4 2.4 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RAI16-like PF10257.9 CDO68335.1 - 7.3e-70 235.6 0.0 1.2e-69 235.0 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein F-box PF00646.33 CDO68336.1 - 0.0005 19.9 0.1 0.0019 18.1 0.1 2.0 1 0 0 1 1 1 1 F-box domain LisH_2 PF16045.5 CDO68336.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 LisH DnaJ PF00226.31 CDO68337.1 - 2.1e-22 79.0 1.8 2.1e-22 79.0 1.8 2.4 2 1 0 2 2 2 1 DnaJ domain DUF2362 PF10154.9 CDO68337.1 - 0.14 11.1 0.6 0.2 10.6 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Seryl_tRNA_N PF02403.22 CDO68337.1 - 0.23 11.7 0.1 0.23 11.7 0.1 3.3 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain TonB_2 PF13103.6 CDO68338.1 - 0.14 12.4 0.1 0.38 11.0 0.0 1.7 2 0 0 2 2 2 0 TonB C terminal DUF575 PF04746.12 CDO68339.1 - 0.094 13.0 2.0 15 5.9 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF575) adh_short PF00106.25 CDO68341.1 - 2.5e-54 183.7 0.8 3.3e-54 183.3 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO68341.1 - 1.9e-35 122.5 0.6 2.6e-35 122.1 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO68341.1 - 4.9e-12 46.1 0.4 6.1e-12 45.8 0.4 1.1 1 0 0 1 1 1 1 KR domain Helicase_RecD PF05127.14 CDO68341.1 - 0.0025 17.7 0.1 0.0041 17.0 0.1 1.3 1 0 0 1 1 1 1 Helicase THF_DHG_CYH_C PF02882.19 CDO68341.1 - 0.021 14.1 0.1 0.06 12.7 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 CDO68341.1 - 0.025 14.7 1.3 0.094 12.8 0.4 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.8 CDO68341.1 - 0.035 13.8 0.9 0.078 12.8 0.9 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4392 PF14336.6 CDO68341.1 - 0.047 13.1 0.1 0.074 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Epimerase PF01370.21 CDO68341.1 - 0.061 12.8 0.3 0.12 11.8 0.3 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CDO68341.1 - 0.12 12.2 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 CDO68341.1 - 0.18 11.2 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Zn_clus PF00172.18 CDO68343.1 - 0.00043 20.4 0.9 0.00043 20.4 0.9 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_rhodopsin PF01036.18 CDO68344.1 - 4.6e-43 147.4 19.6 6.3e-43 146.9 19.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Aldo_ket_red PF00248.21 CDO68345.1 - 9.6e-48 162.9 0.0 1.1e-47 162.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OTU PF02338.19 CDO68346.1 - 6.1e-24 84.9 0.0 1.2e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDO68346.1 - 0.033 13.6 0.0 1.8 7.9 0.0 2.5 2 1 1 3 3 3 0 Peptidase C65 Otubain Adaptin_N PF01602.20 CDO68347.1 - 1.3e-114 383.6 5.9 4.1e-113 378.7 5.9 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDO68347.1 - 1.4e-43 148.7 5.3 3.3e-34 118.3 0.1 3.6 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDO68347.1 - 2.6e-14 53.4 14.0 2.3e-06 27.9 2.4 5.3 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 CDO68347.1 - 7.2e-08 32.0 11.1 0.023 14.9 0.0 6.2 8 0 0 8 8 6 3 HEAT repeat Arm PF00514.23 CDO68347.1 - 2.2e-05 24.3 6.4 0.13 12.3 0.0 5.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 CDO68347.1 - 3.9e-05 23.8 3.3 0.46 10.7 0.7 3.8 2 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CDO68347.1 - 9.9e-05 22.8 6.0 9.1 6.9 0.0 6.1 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 CDO68347.1 - 0.00042 19.9 0.2 0.0083 15.7 0.0 2.8 3 0 0 3 3 3 1 CLASP N terminal HEAT_PBS PF03130.16 CDO68347.1 - 0.11 13.3 1.8 43 5.2 0.2 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RIX1 PF08167.12 CDO68347.1 - 0.13 12.0 0.0 6.1 6.5 0.0 2.9 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis RasGEF_N_2 PF14663.6 CDO68347.1 - 0.16 12.3 2.0 39 4.7 0.0 3.9 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Goodbye PF17109.5 CDO68347.1 - 0.19 12.2 0.8 28 5.2 0.1 2.8 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Pyr_redox_2 PF07992.14 CDO68349.1 - 1.5e-14 54.0 0.0 2.8e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDO68349.1 - 0.0025 17.5 0.2 1.9 8.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CDO68349.1 - 0.023 14.7 0.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Malic_M PF03949.15 CDO68349.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Pyr_redox_3 PF13738.6 CDO68349.1 - 0.15 11.3 0.1 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO68349.1 - 0.19 10.9 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Flg_bb_rod PF00460.20 CDO68350.1 - 0.15 12.0 0.2 0.47 10.5 0.2 1.8 1 0 0 1 1 1 0 Flagella basal body rod protein Cu_bind_like PF02298.17 CDO68351.1 - 2.4e-05 24.2 0.1 5.8e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 CDO68351.1 - 0.024 15.1 0.4 0.076 13.5 0.4 1.8 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Methyltransf_3 PF01596.17 CDO68352.1 - 2.5e-29 102.0 0.0 2.3e-20 72.7 0.0 3.1 3 0 0 3 3 3 3 O-methyltransferase Methyltransf_24 PF13578.6 CDO68352.1 - 4.7e-12 46.9 0.0 1.1e-11 45.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TylF PF05711.11 CDO68352.1 - 0.0031 16.8 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Cons_hypoth95 PF03602.15 CDO68352.1 - 0.043 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MSC PF09402.10 CDO68353.1 - 4.3e-94 315.7 0.0 6e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 CDO68353.1 - 1.3e-10 40.7 0.0 2.8e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain UEV PF05743.13 CDO68354.1 - 3.4e-33 114.1 0.0 5.2e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 CDO68354.1 - 3.5e-18 65.3 0.4 7.7e-18 64.2 0.1 1.7 2 0 0 2 2 2 1 Vps23 core domain TelA PF05816.11 CDO68354.1 - 0.16 11.0 0.1 0.21 10.6 0.1 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) RNA_pol_Rpc34 PF05158.12 CDO68355.1 - 1.7e-76 257.8 1.0 1.5e-67 228.4 0.9 2.1 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit Nucleo_P87 PF07267.11 CDO68355.1 - 4.1 6.1 13.5 6.5 5.5 13.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 CDO68355.1 - 8 5.1 10.1 11 4.6 10.1 1.2 1 0 0 1 1 1 0 Presenilin p450 PF00067.22 CDO68357.1 - 1e-51 176.1 0.0 1.3e-51 175.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MKT1_C PF12246.8 CDO68358.1 - 3.4e-64 216.4 0.0 5.1e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CDO68358.1 - 1.2e-29 102.4 0.0 2.9e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 CDO68358.1 - 1.2e-07 32.2 0.0 2.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CDO68358.1 - 0.019 15.3 0.0 0.082 13.3 0.0 2.0 1 1 0 1 1 1 0 XPG I-region DNA_ligase_A_M PF01068.21 CDO68359.1 - 1.9e-24 86.5 0.0 4.5e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CDO68359.1 - 4.9e-17 62.8 0.0 1.1e-16 61.7 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 CDO68359.1 - 7.4e-06 26.4 0.0 4.2e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 RNA ligase Pirin PF02678.16 CDO68360.1 - 3.4e-25 88.1 3.7 3.6e-24 84.8 3.7 2.1 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 CDO68360.1 - 5.3e-09 35.7 2.4 5.5e-07 29.2 1.3 2.4 2 0 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 CDO68360.1 - 0.0026 17.9 0.0 0.018 15.2 0.0 2.3 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain WD40 PF00400.32 CDO68361.1 - 3.4e-31 106.8 19.9 5.5e-09 36.5 0.3 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO68361.1 - 7.1e-13 48.7 0.1 0.0011 19.2 0.1 3.9 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CDO68361.1 - 1.1e-09 38.6 0.0 2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 CDO68361.1 - 3.6e-05 22.6 0.1 0.07 11.8 0.0 3.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CDO68361.1 - 0.015 14.3 0.0 0.2 10.6 0.0 2.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3169 PF11368.8 CDO68362.1 - 0.039 13.5 3.3 0.063 12.8 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) HAUS6_N PF14661.6 CDO68363.1 - 3.6e-14 52.9 4.9 3.8e-09 36.5 0.1 3.2 4 0 0 4 4 4 2 HAUS augmin-like complex subunit 6 N-terminus Adeno_E1A PF02703.14 CDO68363.1 - 0.048 13.2 1.7 0.086 12.4 1.7 1.4 1 0 0 1 1 1 0 Early E1A protein SPESP1 PF15754.5 CDO68363.1 - 0.087 12.0 0.8 0.23 10.6 0.8 1.8 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Ribosomal_L37e PF01907.19 CDO68364.1 - 1.5e-08 34.6 1.2 3.6e-08 33.5 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L37e RRN3 PF05327.11 CDO68365.1 - 3.7 6.0 5.4 4.3 5.8 5.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1764 PF08576.10 CDO68365.1 - 7.7 7.5 14.8 0.55 11.2 3.2 2.3 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Opi1 PF08618.10 CDO68366.1 - 3.2e-47 161.7 15.7 1.2e-45 156.5 15.7 2.1 1 1 0 1 1 1 1 Transcription factor Opi1 Perilipin PF03036.16 CDO68366.1 - 2.9e-05 23.3 0.1 6.6e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Perilipin family REF PF05755.12 CDO68366.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Herpes_capsid PF06112.11 CDO68368.1 - 8.1 6.5 7.8 2.9 7.9 1.4 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein AATase PF07247.12 CDO68369.1 - 4e-09 35.6 0.0 0.00065 18.4 0.0 2.5 2 1 0 2 2 2 2 Alcohol acetyltransferase DPBB_1 PF03330.18 CDO68369.1 - 0.029 14.6 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Lytic transglycolase Aminotran_3 PF00202.21 CDO68370.1 - 2.6e-82 276.6 0.0 3.2e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CDO68370.1 - 0.05 12.8 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II HAD_2 PF13419.6 CDO68371.1 - 1.2e-09 38.5 0.0 2.6e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDO68371.1 - 7.5e-09 36.2 0.0 1.2e-08 35.6 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDO68371.1 - 0.0027 17.8 0.0 0.0076 16.3 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like AAA PF00004.29 CDO68372.1 - 3.3e-42 144.0 0.1 9.2e-42 142.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DRMBL PF07522.14 CDO68372.1 - 2.7e-28 98.3 0.0 6.5e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Prot_ATP_ID_OB PF16450.5 CDO68372.1 - 2.2e-09 37.1 0.6 4.9e-09 36.0 0.1 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CDO68372.1 - 2.1e-07 30.6 0.1 5.2e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Lactamase_B_2 PF12706.7 CDO68372.1 - 4.5e-07 29.6 0.0 1.8e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain AAA_5 PF07728.14 CDO68372.1 - 1.1e-06 28.6 0.2 7.2e-06 26.0 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDO68372.1 - 2.1e-06 28.2 0.0 0.00067 20.1 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CDO68372.1 - 2.3e-05 24.2 0.0 9.1e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDO68372.1 - 3.1e-05 24.2 0.0 0.00011 22.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDO68372.1 - 0.0016 18.7 0.1 0.022 15.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF3450 PF11932.8 CDO68372.1 - 0.0043 16.4 1.6 0.0082 15.5 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TIP49 PF06068.13 CDO68372.1 - 0.0043 16.3 0.2 0.023 13.9 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain DUF815 PF05673.13 CDO68372.1 - 0.0054 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TsaE PF02367.17 CDO68372.1 - 0.0061 16.6 0.1 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CDO68372.1 - 0.0072 16.7 0.0 0.043 14.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 CDO68372.1 - 0.0072 16.9 0.0 0.023 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 CDO68372.1 - 0.0084 15.7 0.0 0.027 14.1 0.0 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 CDO68372.1 - 0.011 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CDO68372.1 - 0.014 14.9 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CDO68372.1 - 0.021 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CDO68372.1 - 0.026 14.2 0.1 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CDO68372.1 - 0.031 14.4 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CDO68372.1 - 0.04 13.8 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CDO68372.1 - 0.041 14.4 0.1 5.1 7.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CDO68372.1 - 0.045 13.4 0.1 0.27 10.9 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 CDO68372.1 - 0.053 13.6 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CDO68372.1 - 0.06 13.1 1.7 1.1 9.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 CDO68372.1 - 0.063 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Lactamase_B PF00753.27 CDO68372.1 - 0.072 13.1 0.4 0.25 11.3 0.3 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily HBM PF16591.5 CDO68372.1 - 0.077 12.4 1.7 0.13 11.6 1.7 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain PhoH PF02562.16 CDO68372.1 - 0.078 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 CDO68372.1 - 0.12 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.6 CDO68372.1 - 0.14 12.6 2.6 0.31 11.4 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Parvo_NS1 PF01057.17 CDO68372.1 - 0.15 11.2 0.1 0.5 9.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CDO68372.1 - 0.19 11.3 0.5 0.51 9.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain DUF659 PF04937.15 CDO68373.1 - 4e-16 59.2 0.2 7.9e-16 58.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CDO68373.1 - 5.9e-05 22.8 0.9 0.0014 18.4 0.0 2.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Ribosomal_S4e PF00900.20 CDO68374.1 - 4.1e-36 122.7 0.2 9.3e-36 121.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 CDO68374.1 - 3.1e-26 90.8 0.2 6.8e-26 89.7 0.2 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CDO68374.1 - 3.1e-21 75.2 5.8 7.9e-21 73.9 5.8 1.7 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CDO68374.1 - 5.4e-08 32.4 0.3 1.5e-07 31.0 0.0 1.9 3 0 0 3 3 3 1 S4 domain KOW PF00467.29 CDO68374.1 - 0.00033 20.5 2.5 0.0011 18.9 2.5 2.0 1 0 0 1 1 1 1 KOW motif ComC PF03047.14 CDO68374.1 - 0.071 12.9 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 COMC family Sipho_tail PF05709.11 CDO68374.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Phage tail protein GCFC PF07842.12 CDO68375.1 - 3.9e-81 272.7 6.2 6.4e-81 272.0 6.2 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 CDO68375.1 - 2e-14 53.8 9.3 2e-14 53.8 9.3 3.2 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.23 CDO68375.1 - 2.5e-12 46.5 2.9 2.5e-12 46.5 2.9 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CDO68375.1 - 3.8e-09 36.5 5.2 4.7e-07 29.8 1.2 2.9 2 0 0 2 2 2 2 G-patch domain HECT PF00632.25 CDO68376.1 - 3.9e-78 263.0 0.0 5.4e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UIM PF02809.20 CDO68376.1 - 0.094 12.7 2.0 0.62 10.1 2.0 2.5 1 0 0 1 1 1 0 Ubiquitin interaction motif Arm PF00514.23 CDO68376.1 - 0.13 12.4 3.3 2 8.6 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat FAD_binding_3 PF01494.19 CDO68377.1 - 9.3e-88 294.8 0.0 1.4e-87 294.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 CDO68377.1 - 2.7e-35 121.9 0.1 4.4e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 CDO68377.1 - 4.4e-06 25.7 1.2 6.5e-06 25.1 1.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 CDO68377.1 - 2e-05 24.0 0.6 0.00016 21.0 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO68377.1 - 5.3e-05 23.4 0.1 0.00015 21.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDO68377.1 - 0.00012 21.3 2.9 0.0002 20.6 2.3 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 CDO68377.1 - 0.00013 22.4 0.3 0.012 16.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO68377.1 - 0.00025 20.4 0.2 0.0005 19.4 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 CDO68377.1 - 0.00067 19.0 1.0 0.001 18.4 1.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDO68377.1 - 0.0012 18.3 0.7 0.0019 17.6 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 CDO68377.1 - 0.0022 17.7 0.1 0.0042 16.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 CDO68377.1 - 0.0022 17.2 0.8 0.0037 16.4 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CDO68377.1 - 0.0023 17.3 0.3 0.0039 16.5 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 CDO68377.1 - 0.0029 16.7 1.0 0.02 14.0 1.6 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 CDO68377.1 - 0.0043 16.0 0.1 0.0072 15.2 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase TrkA_N PF02254.18 CDO68377.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 CDO68377.1 - 0.033 14.1 0.2 0.057 13.3 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 CDO68377.1 - 0.037 13.7 0.1 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 CDO68377.1 - 0.043 14.3 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.21 CDO68377.1 - 0.067 12.5 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.14 CDO68377.1 - 0.082 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 CDO68377.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 CDO68377.1 - 0.16 11.9 0.2 0.33 10.9 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding UCH PF00443.29 CDO68378.1 - 5.8e-66 222.6 0.0 1.4e-65 221.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDO68378.1 - 1.9e-19 70.5 0.0 3.9e-18 66.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CDO68378.1 - 0.0016 18.9 0.0 0.0039 17.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 CDO68378.1 - 0.0057 16.4 0.3 0.013 15.2 0.3 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger USP8_dimer PF08969.11 CDO68378.1 - 0.029 14.5 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 USP8 dimerisation domain zf-HC5HC2H_2 PF13832.6 CDO68379.1 - 6.5e-20 71.3 2.4 6.5e-20 71.3 2.4 4.3 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CDO68379.1 - 1.2e-15 57.6 1.3 1.2e-15 57.6 1.3 4.6 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 CDO68379.1 - 1.2e-13 50.7 58.0 7.4e-09 35.4 9.3 6.0 6 1 0 6 6 6 3 PHD-finger BAH PF01426.18 CDO68379.1 - 1.7e-12 47.3 0.0 4.4e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.6 CDO68379.1 - 0.00052 19.5 2.8 0.00052 19.5 2.8 6.7 7 0 0 7 7 7 3 PHD-finger GATA PF00320.27 CDO68379.1 - 0.0011 18.5 3.1 0.0011 18.5 3.1 3.7 3 1 0 3 3 3 1 GATA zinc finger Myb_DNA-binding PF00249.31 CDO68379.1 - 0.0013 18.9 0.1 0.0044 17.2 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ELM2 PF01448.24 CDO68379.1 - 0.0073 17.0 0.0 0.022 15.5 0.0 1.9 1 0 0 1 1 1 1 ELM2 domain C1_2 PF03107.16 CDO68379.1 - 0.1 13.0 36.0 0.11 12.9 0.8 6.1 6 1 1 7 7 7 0 C1 domain AT_hook PF02178.19 CDO68379.1 - 0.96 9.5 5.4 2.9 8.1 5.4 1.8 1 0 0 1 1 1 0 AT hook motif FYVE_2 PF02318.16 CDO68379.1 - 0.99 9.6 25.9 0.095 12.9 2.4 4.7 4 0 0 4 4 4 0 FYVE-type zinc finger Aldo_ket_red PF00248.21 CDO68380.1 - 3.3e-08 33.1 0.0 8e-08 31.8 0.0 1.5 2 0 0 2 2 2 1 Aldo/keto reductase family Epimerase PF01370.21 CDO68381.1 - 5.1e-19 68.7 0.2 4.6e-18 65.6 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO68381.1 - 1.9e-12 46.8 0.0 1.6e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CDO68381.1 - 5.8e-10 39.3 0.1 8.3e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CDO68381.1 - 1.7e-09 37.5 0.0 2.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CDO68381.1 - 1.5e-05 24.3 0.3 3.1e-05 23.2 0.3 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CDO68381.1 - 0.0018 17.9 0.3 0.0034 17.0 0.3 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 CDO68381.1 - 0.008 15.4 0.8 0.33 10.1 0.8 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CDO68381.1 - 0.03 13.8 0.3 0.065 12.7 0.3 1.7 1 1 0 1 1 1 0 short chain dehydrogenase p450 PF00067.22 CDO68382.1 - 1.1e-59 202.4 0.0 1.2e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PHF5 PF03660.14 CDO68383.1 - 1.9e-52 175.9 7.9 2.1e-52 175.7 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 CDO68383.1 - 0.038 11.9 4.8 0.042 11.7 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 CDO68383.1 - 0.42 10.7 15.0 1.6 8.8 1.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 CDO68383.1 - 2 8.8 17.7 0.37 11.1 2.7 2.6 1 1 1 2 2 2 0 C1 domain ADH_N PF08240.12 CDO68384.1 - 3.1e-16 59.2 3.4 3.1e-15 56.0 0.8 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO68384.1 - 2.1e-07 31.0 0.7 4.1e-07 30.0 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 CDO68384.1 - 0.011 16.5 0.0 0.019 15.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.21 CDO68384.1 - 0.013 14.8 0.5 0.029 13.7 0.5 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ubie_methyltran PF01209.18 CDO68384.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FAD_binding_3 PF01494.19 CDO68385.1 - 5.4e-79 266.0 0.2 6.7e-79 265.7 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 CDO68385.1 - 1.8e-31 109.4 0.0 8.2e-31 107.3 0.0 2.0 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 CDO68385.1 - 4.8e-05 22.3 0.9 7.6e-05 21.6 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 CDO68385.1 - 0.00018 21.6 0.1 0.00058 20.0 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDO68385.1 - 0.00025 20.4 0.7 0.00048 19.5 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDO68385.1 - 0.0014 18.0 0.7 0.0021 17.4 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDO68385.1 - 0.0021 17.2 9.1 0.0032 16.6 2.7 2.1 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.17 CDO68385.1 - 0.0026 17.0 0.2 0.0047 16.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CDO68385.1 - 0.0061 16.2 0.6 0.013 15.1 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDO68385.1 - 0.0063 17.1 0.9 0.038 14.5 0.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDO68385.1 - 0.01 15.2 3.2 0.016 14.6 3.2 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CDO68385.1 - 0.022 13.6 0.1 0.033 13.0 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 CDO68385.1 - 0.033 13.2 2.7 0.17 10.9 0.9 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CDO68385.1 - 0.062 12.6 0.5 0.1 11.9 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CDO68385.1 - 0.064 12.3 1.7 0.1 11.7 1.7 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 CDO68385.1 - 0.066 13.2 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 CDO68385.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADIP PF11559.8 CDO68386.1 - 2.3e-20 73.2 9.7 2.3e-20 73.2 9.7 3.2 2 1 1 3 3 3 2 Afadin- and alpha -actinin-Binding CCDC144C PF14915.6 CDO68386.1 - 0.0017 17.5 11.3 0.0017 17.5 11.3 2.3 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region DUF2533 PF10752.9 CDO68386.1 - 1.7 9.1 5.5 1.6 9.2 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Erp_C PF06780.11 CDO68386.1 - 2 8.4 4.6 1.1 9.2 0.2 2.7 2 2 1 3 3 3 0 Erp protein C-terminus DUF812 PF05667.11 CDO68386.1 - 3.3 6.5 33.5 0.22 10.4 13.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF3138 PF11336.8 CDO68386.1 - 5.4 5.5 5.8 11 4.4 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Oxidored_molyb PF00174.19 CDO68387.1 - 1.5e-44 151.7 0.0 4.4e-42 143.6 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CDO68387.1 - 2.9e-28 98.6 0.2 5.9e-28 97.6 0.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 CDO68387.1 - 2.1e-20 72.9 0.0 3.9e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CDO68387.1 - 6.2e-13 49.4 0.0 1.6e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 CDO68387.1 - 6.9e-07 29.3 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 2C_adapt PF08793.10 CDO68387.1 - 0.12 12.5 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 2-cysteine adaptor domain HATPase_c PF02518.26 CDO68388.1 - 5.8e-23 81.5 0.0 2.3e-22 79.6 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CDO68388.1 - 1e-17 64.3 0.0 3.4e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 CDO68388.1 - 0.0033 17.4 0.0 0.0096 15.9 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain FAD_binding_3 PF01494.19 CDO68389.1 - 6.3e-45 153.9 0.3 4e-16 59.2 0.0 3.2 1 1 2 3 3 3 3 FAD binding domain Phe_hydrox_dim PF07976.12 CDO68389.1 - 1.2e-27 96.9 0.0 2.6e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 CDO68389.1 - 3.7e-07 29.2 0.5 5.3e-07 28.7 0.5 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 CDO68389.1 - 1.3e-06 27.7 0.2 2.1e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CDO68389.1 - 3e-05 24.2 0.1 9.9e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CDO68389.1 - 8.5e-05 22.0 0.3 0.00012 21.4 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDO68389.1 - 8.6e-05 21.9 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO68389.1 - 0.0004 19.7 0.1 0.00071 18.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CDO68389.1 - 0.0006 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CDO68389.1 - 0.00093 18.3 0.7 0.0015 17.7 0.7 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 CDO68389.1 - 0.0028 16.8 0.1 0.0039 16.3 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CDO68389.1 - 0.0034 17.9 0.1 0.01 16.4 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDO68389.1 - 0.022 14.1 0.4 0.034 13.5 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CDO68389.1 - 0.032 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 CDO68389.1 - 0.043 13.8 0.2 0.096 12.7 0.1 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 CDO68389.1 - 0.059 13.6 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 CDO68389.1 - 0.073 11.9 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 CDO68389.1 - 0.087 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 CDO68389.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 CDO68389.1 - 0.13 12.7 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Paf1 PF03985.13 CDO68390.1 - 9.9e-71 239.0 0.0 1.2e-70 238.7 0.0 1.0 1 0 0 1 1 1 1 Paf1 APH PF01636.23 CDO68393.1 - 8.3e-12 45.5 0.1 8.3e-12 45.5 0.1 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family F-box-like PF12937.7 CDO68393.1 - 3e-10 39.8 1.7 7.8e-10 38.5 1.7 1.8 1 0 0 1 1 1 1 F-box-like RIO1 PF01163.22 CDO68393.1 - 0.0006 19.5 0.0 1.3 8.6 0.0 3.3 3 0 0 3 3 3 2 RIO1 family LRR_4 PF12799.7 CDO68393.1 - 0.0025 18.2 2.1 1.1 9.8 0.0 4.5 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) Choline_kinase PF01633.20 CDO68393.1 - 0.0033 17.0 0.1 0.013 15.1 0.0 2.0 3 0 0 3 3 3 1 Choline/ethanolamine kinase F-box PF00646.33 CDO68393.1 - 0.019 14.9 4.2 0.25 11.2 0.8 3.1 2 0 0 2 2 2 0 F-box domain Pkinase_Tyr PF07714.17 CDO68393.1 - 0.067 12.5 0.1 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase Evr1_Alr PF04777.13 CDO68394.1 - 3.4e-30 104.5 1.2 6.8e-30 103.5 0.2 1.9 2 0 0 2 2 2 1 Erv1 / Alr family DUF3498 PF12004.8 CDO68394.1 - 1.9 7.6 7.3 2.7 7.1 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Glyco_hydro_47 PF01532.20 CDO68395.1 - 3.7e-134 448.1 0.0 4.3e-134 447.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_S28 PF05577.12 CDO68396.1 - 5.3e-57 193.5 0.8 4.2e-56 190.6 0.8 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase S28 WD40 PF00400.32 CDO68396.1 - 9.8e-06 26.2 1.0 0.2 12.6 0.0 4.1 3 1 0 3 3 3 2 WD domain, G-beta repeat CRAL_TRIO PF00650.20 CDO68397.1 - 4.9e-28 97.8 0.0 7.6e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDO68397.1 - 0.0047 17.1 0.0 0.0098 16.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SDA1 PF05285.12 CDO68397.1 - 0.12 11.8 1.4 0.3 10.5 1.1 1.7 2 0 0 2 2 2 0 SDA1 CRAL_TRIO_2 PF13716.6 CDO68397.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Histone PF00125.24 CDO68398.1 - 6e-50 169.0 4.1 6.7e-50 168.8 4.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDO68398.1 - 2.1e-05 24.6 0.1 3.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CDO68398.1 - 4.5e-05 23.8 0.0 7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CDO68398.1 - 0.00012 22.6 1.7 0.00016 22.3 1.7 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CDO68398.1 - 0.0028 17.9 0.1 0.0055 17.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CDO68399.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CDO68399.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CDO68399.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CDO68399.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDO68399.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CDO68399.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit F-box-like PF12937.7 CDO68400.1 - 5.3e-08 32.6 0.1 1.2e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO68400.1 - 0.00027 20.7 0.2 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 CDO68400.1 - 0.095 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 F-box RhoGAP PF00620.27 CDO68401.1 - 5.2e-48 162.7 0.0 1.1e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 CDO68401.1 - 1.1e-14 54.5 2.2 3.1e-14 53.0 0.1 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SKA2 PF16740.5 CDO68401.1 - 0.28 11.0 7.6 0.044 13.6 1.6 2.5 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 CDO68401.1 - 0.29 11.2 1.1 8.9 6.4 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CDO68401.1 - 1.9 8.7 5.9 1.8 8.7 2.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 CDO68401.1 - 3.9 7.3 9.6 0.21 11.4 2.8 2.3 3 0 0 3 3 3 0 Septum formation initiator Zip PF02535.22 CDO68402.1 - 2.2e-64 217.8 6.4 2.5e-64 217.6 6.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter CHRD PF07452.12 CDO68403.1 - 0.02 15.9 0.1 0.025 15.5 0.1 1.4 1 1 0 1 1 1 0 CHRD domain DEAD PF00270.29 CDO68404.1 - 1.9e-40 138.5 0.1 3.5e-40 137.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO68404.1 - 5.2e-29 100.8 0.0 3.9e-28 98.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO68404.1 - 5.7e-06 26.4 0.0 2.2e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 CDO68404.1 - 0.069 11.4 0.6 0.088 11.1 0.6 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_19 PF13245.6 CDO68404.1 - 0.094 13.1 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 CDO68405.1 - 3e-10 39.9 0.0 4.2e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Dynactin_p22 PF07426.11 CDO68407.1 - 3.2e-17 62.9 2.8 1e-16 61.2 2.8 1.7 1 1 0 1 1 1 1 Dynactin subunit p22 Lebercilin PF15619.6 CDO68407.1 - 0.0023 17.7 9.4 0.0066 16.1 2.0 2.2 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease REV1_C PF16727.5 CDO68407.1 - 0.0058 17.0 0.4 0.016 15.6 0.4 1.7 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain MscS_porin PF12795.7 CDO68407.1 - 0.0073 15.9 2.3 0.015 14.9 2.3 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Cortex-I_coil PF09304.10 CDO68407.1 - 0.051 13.8 8.3 0.08 13.2 0.5 3.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil Laminin_I PF06008.14 CDO68407.1 - 0.065 12.9 4.1 0.11 12.1 4.2 1.3 1 1 0 1 1 1 0 Laminin Domain I APG6_N PF17675.1 CDO68407.1 - 0.68 10.5 6.5 7.8 7.0 6.5 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region SHNi-TPR PF10516.9 CDO68408.1 - 1.6e-15 56.3 0.1 2.4e-13 49.3 0.0 2.9 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 CDO68408.1 - 5.3e-11 42.6 13.9 1e-05 25.8 0.2 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDO68408.1 - 4.9e-06 26.1 0.1 0.44 10.5 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO68408.1 - 0.0028 17.3 5.2 2 8.2 0.3 4.5 4 1 0 4 4 4 2 TPR repeat TPR_2 PF07719.17 CDO68408.1 - 0.0035 17.4 12.4 0.94 9.8 0.0 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDO68408.1 - 0.021 15.0 8.4 1.8 9.0 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDO68408.1 - 0.086 13.4 12.9 0.46 11.0 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDO68408.1 - 0.52 10.5 3.8 35 4.7 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDO68408.1 - 0.81 10.7 12.2 2.5 9.2 0.5 5.4 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDO68408.1 - 1.1 9.9 13.1 7.3 7.3 1.3 4.6 3 2 2 5 5 5 0 Tetratricopeptide repeat Aldedh PF00171.22 CDO68409.1 - 4.6e-17 61.7 8.0 1.5e-12 46.8 6.9 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family FGGY_N PF00370.21 CDO68410.1 - 2.5e-62 210.6 0.1 1.5e-60 204.9 0.1 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CDO68410.1 - 7.2e-60 202.1 1.1 1.2e-59 201.4 1.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain SANT_DAMP1_like PF16282.5 CDO68410.1 - 0.19 12.0 0.6 0.5 10.6 0.1 2.0 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Glyco_hydro_47 PF01532.20 CDO68411.1 - 1.7e-120 403.0 0.0 2.1e-120 402.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ANTH PF07651.16 CDO68412.1 - 1.5e-55 188.1 0.1 2.3e-55 187.5 0.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 CDO68412.1 - 0.00014 21.9 0.0 0.00034 20.7 0.0 1.7 1 0 0 1 1 1 1 ENTH domain FerA PF08165.11 CDO68412.1 - 0.11 12.4 1.2 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 FerA (NUC095) domain ABC_transp_aux PF09822.9 CDO68412.1 - 0.14 11.6 1.9 10 5.5 0.0 3.0 2 1 0 2 2 2 0 ABC-type uncharacterized transport system F-box PF00646.33 CDO68412.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 F-box domain E1-E2_ATPase PF00122.20 CDO68415.1 - 3.8e-48 163.4 2.4 3.8e-48 163.4 2.4 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CDO68415.1 - 1.6e-30 107.0 0.2 3.6e-30 105.8 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CDO68415.1 - 7.4e-28 96.8 0.0 1.6e-13 50.9 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CDO68415.1 - 0.0004 20.2 0.4 0.028 14.2 0.2 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase 7TM_GPCR_Srh PF10318.9 CDO68415.1 - 0.14 11.2 1.9 2.2 7.2 0.3 2.4 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh DGF-1_4 PF11024.8 CDO68415.1 - 1.5 9.7 4.4 1.6 9.6 0.4 3.0 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Myb_DNA-bind_3 PF12776.7 CDO68417.1 - 7e-09 36.6 0.0 1.3e-08 35.8 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO68417.1 - 1.7e-08 34.7 0.1 3.5e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO68417.1 - 0.00094 19.2 0.3 0.0045 17.0 0.1 2.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CDO68417.1 - 0.055 13.7 0.7 0.14 12.4 0.7 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain TAL_effector PF03377.13 CDO68417.1 - 0.067 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 TAL effector repeat Reprolysin_4 PF13583.6 CDO68417.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SNARE_assoc PF09335.11 CDO68418.1 - 0.37 11.3 6.9 0.17 12.4 4.8 1.5 1 1 0 1 1 1 0 SNARE associated Golgi protein RVT_2 PF07727.14 CDO68419.1 - 3e-68 230.1 0.0 4.3e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CDO68419.1 - 3.5e-22 78.6 0.0 5.6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO68419.1 - 6.9e-06 25.8 0.0 2.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 CDO68419.1 - 0.00038 20.6 0.1 0.01 16.0 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 CDO68419.1 - 0.0055 16.7 1.8 0.0055 16.7 1.8 1.8 2 0 0 2 2 2 1 Zinc knuckle CCDC53 PF10152.9 CDO68419.1 - 0.64 10.4 8.9 1 9.8 4.5 2.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Pkinase_fungal PF17667.1 CDO68421.1 - 1.5e-27 96.5 0.2 2.7e-18 66.0 0.0 2.2 1 1 1 2 2 2 2 Fungal protein kinase SecY PF00344.20 CDO68422.1 - 6.4e-74 249.0 8.6 8e-74 248.6 8.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CDO68422.1 - 7.5e-19 67.3 0.2 4.4e-18 64.8 0.2 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p DUF4235 PF14019.6 CDO68422.1 - 0.084 13.0 0.3 2.6 8.2 0.6 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4235) Claudin_3 PF06653.11 CDO68422.1 - 2.3 8.1 0.0 2.3 8.1 0.0 3.3 4 0 0 4 4 4 0 Tight junction protein, Claudin-like ATG7_N PF16420.5 CDO68423.1 - 1.5e-89 300.6 0.0 1.8e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CDO68423.1 - 8.9e-06 25.2 0.0 0.0015 17.9 0.1 2.2 1 1 1 2 2 2 2 ThiF family Adeno_PIX PF03955.14 CDO68424.1 - 0.13 12.4 0.8 0.32 11.2 0.3 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) EspF PF04806.12 CDO68424.1 - 0.82 10.1 2.8 9.8 6.7 0.5 2.5 2 0 0 2 2 2 0 EspF protein repeat p450 PF00067.22 CDO68425.1 - 4.3e-67 226.9 0.0 2.4e-66 224.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_60s PF00428.19 CDO68426.1 - 2.5e-28 98.5 9.2 3.1e-28 98.2 9.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Etmic-2 PF06670.11 CDO68426.1 - 0.0047 15.9 0.8 0.0051 15.8 0.8 1.0 1 0 0 1 1 1 1 Microneme protein Etmic-2 BTB PF00651.31 CDO68427.1 - 0.057 13.6 0.1 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain EthD PF07110.11 CDO68428.1 - 0.00012 23.2 0.1 0.029 15.5 0.0 2.8 2 1 0 2 2 2 2 EthD domain EthD PF07110.11 CDO68429.1 - 1.5e-09 38.8 0.0 0.00083 20.5 0.0 2.3 2 0 0 2 2 2 2 EthD domain ABM PF03992.16 CDO68429.1 - 0.015 15.4 0.2 0.044 13.9 0.1 1.8 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase BTB PF00651.31 CDO68431.1 - 0.091 13.0 0.0 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Stevor PF17410.2 CDO68432.1 - 0.15 11.6 2.1 0.27 10.7 1.7 1.5 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4381 PF14316.6 CDO68432.1 - 0.16 12.2 0.2 0.27 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Sod_Fe_C PF02777.18 CDO68435.1 - 5.7e-37 126.0 0.3 1.1e-36 125.1 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CDO68435.1 - 1e-31 109.2 3.9 1.5e-31 108.7 2.5 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pkinase_fungal PF17667.1 CDO68436.1 - 1.1e-25 90.2 0.0 5.1e-20 71.6 0.0 2.3 1 1 1 2 2 2 2 Fungal protein kinase RVT_2 PF07727.14 CDO68437.1 - 1.3e-78 264.0 0.1 2e-78 263.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO68437.1 - 5.6e-21 74.9 0.0 1.3e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO68437.1 - 6.6e-09 35.5 0.1 1.5e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO68437.1 - 0.00018 21.2 0.1 0.00043 20.0 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain RNA_polI_A34 PF08208.11 CDO68437.1 - 1.6 8.8 4.7 3.6 7.6 4.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 LPD39 PF18858.1 CDO68439.1 - 0.039 14.1 0.4 0.083 13.0 0.4 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 Gemini_AC4_5_2 PF08464.10 CDO68439.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Glyco_transf_24 PF18404.1 CDO68442.1 - 1.3e-102 342.8 3.7 1.7e-101 339.2 3.7 2.1 1 1 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CDO68442.1 - 5.2e-67 226.5 0.0 1.3e-63 215.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 CDO68442.1 - 6.7e-44 150.0 0.0 1.1e-43 149.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CDO68442.1 - 2.1e-41 140.5 0.0 4.8e-41 139.3 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 CDO68442.1 - 4.9e-40 136.6 0.0 6.9e-39 132.9 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 CDO68442.1 - 2e-30 106.3 0.0 7.3e-30 104.5 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 CDO68442.1 - 4.5e-06 26.4 0.0 9.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Pkinase PF00069.25 CDO68443.1 - 4.5e-73 245.9 0.0 6.9e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO68443.1 - 1.9e-44 151.9 0.0 3.3e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CDO68443.1 - 1.1e-37 128.0 1.3 2.6e-19 69.2 0.2 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CDO68443.1 - 3.8e-08 33.0 0.0 1.5e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDO68443.1 - 0.0011 18.0 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDO68443.1 - 0.0043 16.4 0.1 0.024 14.0 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2076 PF09849.9 CDO68443.1 - 0.015 15.4 13.2 0.023 14.7 1.6 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4520 PF15016.6 CDO68443.1 - 0.04 14.0 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) DUF1156 PF06634.12 CDO68443.1 - 0.15 12.2 0.1 2.5 8.2 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1156) CENP-Q PF13094.6 CDO68444.1 - 0.02 15.1 1.1 0.02 15.1 1.1 2.2 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3713 PF12506.8 CDO68444.1 - 0.025 14.9 0.3 0.051 13.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) Nsp1_C PF05064.13 CDO68444.1 - 0.028 14.2 0.6 0.19 11.5 0.0 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region V_ATPase_I PF01496.19 CDO68444.1 - 0.053 11.4 1.0 0.066 11.1 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2934 PF11154.8 CDO68444.1 - 0.069 12.8 0.3 0.2 11.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) NPV_P10 PF05531.12 CDO68444.1 - 0.097 13.1 1.8 2.3 8.8 0.4 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FOXP-CC PF16159.5 CDO68444.1 - 0.097 13.3 2.5 0.2 12.3 1.5 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain SlyX PF04102.12 CDO68444.1 - 0.17 12.5 5.0 28 5.4 1.4 3.6 3 1 0 3 3 3 0 SlyX TBCA PF02970.16 CDO68444.1 - 0.5 10.7 5.5 0.44 10.9 0.6 2.8 3 1 0 3 3 3 0 Tubulin binding cofactor A TPR_MLP1_2 PF07926.12 CDO68444.1 - 0.55 10.3 11.0 0.22 11.6 2.4 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein MutS_III PF05192.18 CDO68444.1 - 0.61 10.3 3.2 0.88 9.8 3.2 1.3 1 0 0 1 1 1 0 MutS domain III Baculo_PEP_C PF04513.12 CDO68444.1 - 0.77 9.8 3.7 5.4 7.0 3.7 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.6 CDO68444.1 - 1.7 9.1 9.6 6.5 7.2 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FUSC PF04632.12 CDO68444.1 - 2.5 6.6 5.9 3 6.3 5.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fzo_mitofusin PF04799.13 CDO68444.1 - 3.9 7.0 6.3 26 4.3 0.2 2.5 1 1 0 2 2 2 0 fzo-like conserved region DivIC PF04977.15 CDO68444.1 - 6.3 6.7 7.8 0.41 10.4 1.4 2.4 3 0 0 3 3 3 0 Septum formation initiator Retrotrans_gag PF03732.17 CDO68445.1 - 1.4e-05 25.3 0.6 3.1e-05 24.2 0.6 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein tRNA_m1G_MT PF01746.21 CDO68447.1 - 2.4e-24 86.1 0.5 3e-21 76.0 0.2 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase SR-25 PF10500.9 CDO68447.1 - 4.7 6.7 20.0 0.9 9.1 13.8 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Methyltransf_23 PF13489.6 CDO68448.1 - 4.9e-08 33.0 0.0 3.8e-06 26.8 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO68448.1 - 7.1e-05 23.4 0.0 0.00015 22.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO68448.1 - 0.00037 21.2 0.0 0.00087 20.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO68448.1 - 0.047 14.4 0.0 0.13 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CDO68448.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FOXP-CC PF16159.5 CDO68449.1 - 0.0025 18.4 8.1 1.1 10.0 1.1 3.5 3 0 0 3 3 3 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CDO68449.1 - 0.011 16.0 4.9 0.03 14.6 3.6 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CDO68449.1 - 0.032 14.7 14.3 3.5 8.2 3.4 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO68449.1 - 0.059 14.2 13.0 7.3 7.7 2.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger RNA_pol_Rpb2_6 PF00562.28 CDO68451.1 - 5.6e-113 377.9 0.0 1.2e-112 376.9 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDO68451.1 - 4.4e-36 124.3 0.0 7.2e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CDO68451.1 - 1.2e-28 99.1 0.0 3.2e-28 97.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CDO68451.1 - 3.5e-24 84.6 0.0 9.4e-24 83.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 CDO68451.1 - 3.4e-22 79.0 0.0 8.1e-22 77.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CDO68451.1 - 4.1e-19 68.8 0.2 3.6e-15 56.1 0.1 2.7 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 Nucleoporin2 PF04096.14 CDO68452.1 - 1.5e-46 158.2 0.0 2.2e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 CDO68452.1 - 1.9e-15 57.5 299.9 2.9e-07 31.2 40.7 11.4 5 3 5 10 10 10 5 Nucleoporin FG repeat region Yae1_N PF09811.9 CDO68453.1 - 0.0099 15.6 4.7 0.017 14.8 4.7 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF4404 PF14357.6 CDO68453.1 - 5.3 7.8 5.9 9 7.0 5.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) YkpC PF17447.2 CDO68454.1 - 0.6 11.0 0.6 0.6 11.0 0.6 3.2 3 0 0 3 3 3 0 Uncharacterized YkpC-like ABC_tran PF00005.27 CDO68455.1 - 6.6e-16 59.1 0.2 2.6e-15 57.1 0.2 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDO68455.1 - 4e-12 46.6 1.8 3e-05 24.0 0.3 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CDO68455.1 - 0.00021 20.9 0.3 0.00041 20.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDO68455.1 - 0.00039 20.1 0.3 0.0012 18.6 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CDO68455.1 - 0.002 17.9 0.1 0.0028 17.4 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDO68455.1 - 0.0027 17.6 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 CDO68455.1 - 0.0031 18.1 0.2 0.0045 17.5 0.2 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 CDO68455.1 - 0.0084 15.6 0.8 0.43 10.0 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CDO68455.1 - 0.035 14.4 0.1 0.12 12.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CDO68455.1 - 0.041 14.0 0.1 0.076 13.1 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.22 CDO68455.1 - 0.05 13.2 0.1 0.078 12.6 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 CDO68455.1 - 0.053 13.4 0.3 0.32 10.9 0.2 2.0 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 CDO68455.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 CDO68455.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_33 PF13671.6 CDO68455.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Opy2 PF09463.10 CDO68456.1 - 3.2e-06 27.3 15.5 5.1e-06 26.7 15.5 1.3 1 0 0 1 1 1 1 Opy2 protein VSP PF03302.13 CDO68456.1 - 0.0053 15.7 4.9 0.0094 14.9 4.9 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein OppC_N PF12911.7 CDO68456.1 - 0.024 14.6 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C SKG6 PF08693.10 CDO68456.1 - 0.053 12.9 6.0 0.13 11.7 6.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SKG6 PF08693.10 CDO68457.1 - 2e-06 27.1 3.7 3.9e-06 26.2 3.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Opy2 PF09463.10 CDO68457.1 - 0.0075 16.6 6.1 0.011 16.0 6.1 1.2 1 0 0 1 1 1 1 Opy2 protein DUF4448 PF14610.6 CDO68457.1 - 0.012 15.4 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.16 CDO68457.1 - 0.05 12.3 0.2 0.059 12.1 0.2 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E zf-CCHC PF00098.23 CDO68458.1 - 0.51 10.5 32.9 2 8.6 9.5 4.5 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.6 CDO68458.1 - 1.6 8.8 19.6 0.7 9.9 4.1 3.9 2 1 1 3 3 3 0 Zinc knuckle UQ_con PF00179.26 CDO68460.1 - 1.2e-10 41.2 0.1 2.7e-10 40.0 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Mito_carr PF00153.27 CDO68461.1 - 3.1e-46 155.3 0.7 2.5e-17 62.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Retrotran_gag_2 PF14223.6 CDO68465.1 - 8.8e-23 80.5 0.0 1.1e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Med15 PF09606.10 CDO68465.1 - 0.28 9.8 1.9 0.35 9.5 1.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Tfb5 PF06331.12 CDO68466.1 - 2.6e-20 72.2 1.2 3.5e-20 71.7 0.4 1.6 2 0 0 2 2 2 1 Transcription factor TFIIH complex subunit Tfb5 DUF2554 PF10829.8 CDO68466.1 - 0.096 13.1 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) Nucleoporin_FG PF13634.6 CDO68467.1 - 4.9e-14 52.9 107.5 1e-06 29.5 25.9 4.5 1 1 2 3 3 3 2 Nucleoporin FG repeat region G3P_antiterm PF04309.12 CDO68467.1 - 0.022 14.2 0.1 0.034 13.6 0.1 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Glyco_transf_17 PF04724.13 CDO68468.1 - 1.1e-137 458.8 0.0 1.2e-137 458.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Actin PF00022.19 CDO68469.1 - 1.6e-26 92.9 0.0 1.7e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 Actin Transposase_21 PF02992.14 CDO68471.1 - 2e-23 82.8 1.9 3.9e-23 81.8 0.0 2.4 4 0 0 4 4 4 1 Transposase family tnp2 DUF4218 PF13960.6 CDO68471.1 - 4e-06 26.4 0.2 1.6e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Ribonuc_2-5A PF06479.12 CDO68471.1 - 0.099 12.8 0.4 0.25 11.5 0.4 1.6 1 0 0 1 1 1 0 Ribonuclease 2-5A PX PF00787.24 CDO68472.1 - 0.004 17.1 0.0 0.017 15.1 0.0 2.0 1 1 0 1 1 1 1 PX domain Aldo_ket_red PF00248.21 CDO68473.1 - 3.1e-66 223.6 0.0 3.6e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GIIM PF08388.11 CDO68473.1 - 0.034 14.2 0.1 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Group II intron, maturase-specific domain GATA PF00320.27 CDO68474.1 - 5.3e-15 54.7 3.8 5.3e-15 54.7 3.8 1.8 2 0 0 2 2 2 1 GATA zinc finger TauD PF02668.16 CDO68475.1 - 1.3e-54 185.8 1.7 2.7e-54 184.8 1.7 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UCH PF00443.29 CDO68477.1 - 3.1e-42 144.9 0.0 4e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDO68477.1 - 9.5e-22 78.0 0.0 1.1e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CDO68477.1 - 0.012 15.0 1.7 0.18 11.3 0.8 2.3 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3292 PF11696.8 CDO68478.1 - 3.8e-216 719.4 0.0 2.8e-215 716.6 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) CPSase_L_D2 PF02786.17 CDO68478.1 - 8.6e-69 231.2 0.0 5.5e-68 228.6 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 CDO68478.1 - 1.3e-31 108.9 0.0 4.8e-30 103.8 0.0 2.9 2 1 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 CDO68478.1 - 4.8e-18 65.7 0.0 2.2e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Dala_Dala_lig_C PF07478.13 CDO68478.1 - 4.4e-09 36.2 0.0 8.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CDO68478.1 - 4.6e-08 32.8 0.0 2.8e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain PRT_C PF08372.10 CDO68478.1 - 0.0032 17.2 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal ATP-grasp_4 PF13535.6 CDO68478.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain F-box-like PF12937.7 CDO68480.1 - 3.8e-10 39.5 0.1 1.2e-09 37.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO68480.1 - 0.00082 19.2 3.6 0.0011 18.8 0.0 2.8 3 0 0 3 3 3 1 F-box domain ELYS PF13934.6 CDO68480.1 - 0.093 12.7 0.9 0.34 10.9 0.1 2.2 2 1 0 2 2 2 0 Nuclear pore complex assembly DUF3176 PF11374.8 CDO68480.1 - 0.11 12.7 0.9 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) DUF3292 PF11696.8 CDO68481.1 - 8.1e-154 513.5 0.0 1.4e-87 294.6 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.10 CDO68481.1 - 0.00057 19.7 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal UCH PF00443.29 CDO68482.1 - 6.1e-41 140.6 0.0 2.8e-39 135.1 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 CDO68482.1 - 1.7e-26 91.9 2.6 2.2e-17 62.7 0.0 3.0 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.6 CDO68482.1 - 2.4e-08 34.0 0.2 0.003 17.2 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase NnrU PF07298.11 CDO68482.1 - 0.014 14.9 0.8 0.035 13.6 0.8 1.6 1 0 0 1 1 1 0 NnrU protein DUF4633 PF15464.6 CDO68482.1 - 0.1 12.8 1.8 0.19 11.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) LapA_dom PF06305.11 CDO68482.1 - 0.19 11.6 1.2 0.68 9.8 1.2 2.0 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Fes1 PF08609.10 CDO68482.1 - 0.2 12.6 2.1 1.5 9.7 0.1 3.0 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Tmemb_cc2 PF10267.9 CDO68482.1 - 0.25 10.5 1.0 0.47 9.5 1.0 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein ABC_ATPase PF09818.9 CDO68483.1 - 2.6e-133 445.1 0.0 1e-128 430.0 0.0 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 CDO68483.1 - 0.0066 17.0 0.0 0.011 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDO68483.1 - 0.0077 15.9 0.2 0.017 14.9 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CDO68483.1 - 0.018 14.6 0.0 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain TraV PF09676.10 CDO68483.1 - 0.17 12.8 0.0 0.39 11.7 0.0 1.5 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) HET PF06985.11 CDO68484.1 - 1.8e-16 60.8 5.1 1.8e-16 60.8 5.1 2.4 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 CDO68484.1 - 7.4e-08 32.9 0.3 0.0082 17.0 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO68484.1 - 0.0049 17.1 0.1 1.8 8.9 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain HET PF06985.11 CDO68485.1 - 5.8e-11 42.9 6.7 8.7e-10 39.1 1.4 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 CDO68485.1 - 1.9e-08 34.5 0.0 0.00078 19.7 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDO68485.1 - 3e-08 34.2 1.7 0.048 14.5 0.1 5.4 4 1 0 4 4 4 2 WD domain, G-beta repeat NAD_binding_1 PF00175.21 CDO68486.1 - 6.7e-29 100.7 0.0 9.7e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CDO68486.1 - 2.1e-18 66.5 0.0 4.7e-18 65.4 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CDO68486.1 - 9.5e-06 25.8 0.0 8.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CDO68486.1 - 0.21 11.8 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Pkinase PF00069.25 CDO68487.1 - 5.2e-59 199.8 0.0 4.2e-58 196.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO68487.1 - 5.4e-25 88.1 0.0 6.9e-24 84.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PHP PF02811.19 CDO68488.1 - 5.7e-11 43.0 0.0 6.2e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 PHP domain Sel1 PF08238.12 CDO68490.1 - 1.5e-47 158.9 31.8 2.5e-10 40.7 0.1 8.4 9 0 0 9 9 9 7 Sel1 repeat TPR_5 PF12688.7 CDO68490.1 - 0.11 12.7 0.5 0.64 10.3 0.0 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_16 PF13432.6 CDO68490.1 - 0.69 10.6 25.0 1.7 9.3 0.5 5.1 3 2 2 5 5 5 0 Tetratricopeptide repeat Plavaka PF18759.1 CDO68492.1 - 4.7e-22 78.6 0.0 8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Nop14 PF04147.12 CDO68492.1 - 0.11 10.8 0.4 1.3 7.2 0.0 2.0 2 0 0 2 2 2 0 Nop14-like family Pkinase_fungal PF17667.1 CDO68493.1 - 3.8e-29 101.7 0.0 8.7e-19 67.6 0.0 2.3 1 1 1 2 2 2 2 Fungal protein kinase F-box PF00646.33 CDO68494.1 - 0.052 13.5 0.3 0.29 11.1 0.0 2.4 3 0 0 3 3 3 0 F-box domain C2 PF00168.30 CDO68495.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 C2 domain ubiquitin PF00240.23 CDO68496.1 - 1.9e-21 75.6 0.1 3.1e-21 74.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CDO68496.1 - 7.2e-12 45.0 0.1 1.8e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 CDO68496.1 - 4.7e-11 42.4 0.1 7.9e-11 41.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDO68496.1 - 2.3e-06 28.1 0.0 4.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDO68496.1 - 0.0011 19.0 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CDO68496.1 - 0.002 18.0 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDO68496.1 - 0.01 15.8 0.4 1.1 9.4 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain Phage_tail_X PF05489.12 CDO68496.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X Ubiquitin_5 PF18037.1 CDO68496.1 - 0.034 14.5 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CDO68496.1 - 0.036 14.5 0.2 0.11 13.0 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain RPN13_C PF16550.5 CDO68496.1 - 0.037 14.2 1.9 0.71 10.1 0.8 2.6 1 1 1 2 2 2 0 UCH-binding domain HOIP-UBA PF16678.5 CDO68496.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair STI1 PF17830.1 CDO68496.1 - 0.18 11.8 9.5 4.7 7.2 0.2 2.7 2 0 0 2 2 2 0 STI1 domain GerD PF17898.1 CDO68496.1 - 0.2 11.6 3.4 0.86 9.6 3.4 2.0 1 1 0 1 1 1 0 Spore germination GerD central core domain CUE PF02845.16 CDO68496.1 - 6.8 6.5 5.7 2.7 7.8 0.0 2.7 3 0 0 3 3 3 0 CUE domain Dus PF01207.17 CDO68497.1 - 7.8e-71 238.7 0.0 1e-70 238.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 CDO68497.1 - 0.00021 21.1 0.1 0.036 13.8 0.1 2.3 1 1 1 2 2 2 2 SOR/SNZ family NMO PF03060.15 CDO68497.1 - 0.00043 19.8 0.0 0.00078 18.9 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 CDO68497.1 - 0.0035 16.7 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 CDO68497.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 CDO68497.1 - 0.018 14.2 0.0 0.04 13.1 0.0 1.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 CDO68497.1 - 0.098 12.1 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein HATPase_c PF02518.26 CDO68498.1 - 6.3e-25 87.9 0.0 1.4e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CDO68498.1 - 1.7e-24 86.1 0.0 3.8e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain MHYT PF03707.16 CDO68498.1 - 1.8e-24 85.7 23.0 1.8e-12 47.2 2.3 4.4 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat HisKA PF00512.25 CDO68498.1 - 1e-14 54.3 0.0 3.8e-14 52.5 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 CDO68498.1 - 0.00042 20.2 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 GHKL domain MFS_1_like PF12832.7 CDO68498.1 - 0.013 14.4 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 MFS_1 like family YbhQ PF11076.8 CDO68498.1 - 0.17 11.9 1.6 0.39 10.7 1.6 1.6 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ BofA PF07441.11 CDO68498.1 - 0.25 11.6 3.7 0.25 11.6 1.7 2.0 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA SPX PF03105.19 CDO68498.1 - 1.5 8.7 12.7 2.5 7.9 12.7 1.2 1 0 0 1 1 1 0 SPX domain Tetraspanin PF00335.20 CDO68499.1 - 1e-10 41.7 6.7 1.3e-10 41.4 6.7 1.1 1 0 0 1 1 1 1 Tetraspanin family FTR1 PF03239.14 CDO68499.1 - 0.012 14.9 0.2 0.022 14.0 0.2 1.4 1 0 0 1 1 1 0 Iron permease FTR1 family iPGM_N PF06415.13 CDO68500.1 - 6.9e-80 267.5 0.1 1e-79 267.0 0.1 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 CDO68500.1 - 6.9e-72 241.8 1.4 8e-72 241.6 1.4 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CDO68500.1 - 0.00014 21.4 0.0 0.00095 18.7 0.0 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CDO68500.1 - 0.00063 19.4 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 CDO68500.1 - 0.0037 17.4 0.1 0.0089 16.1 0.1 1.6 1 0 0 1 1 1 1 PglZ domain DLH PF01738.18 CDO68501.1 - 1.4e-08 34.6 0.1 2.4e-07 30.6 0.1 2.5 1 1 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 CDO68502.1 - 2.6e-18 66.4 0.0 3.1e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Hus1 PF04005.12 CDO68503.1 - 8.5e-49 166.2 0.0 1e-34 120.0 0.0 2.1 1 1 1 2 2 2 2 Hus1-like protein PCNA_C PF02747.15 CDO68503.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain Kdo PF06293.14 CDO68506.1 - 4.4e-09 36.0 0.0 3.3e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO68506.1 - 2.5e-05 24.3 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDO68506.1 - 4.3e-05 23.0 0.0 6.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 CDO68506.1 - 9.5e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDO68506.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CDO68506.1 - 0.024 14.2 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 RIO1 family PfkB PF00294.24 CDO68506.1 - 0.13 11.5 0.0 1.9 7.7 0.0 2.1 2 0 0 2 2 2 0 pfkB family carbohydrate kinase NIF PF03031.18 CDO68507.1 - 2.2e-15 56.7 0.0 1.2e-14 54.4 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase EamA PF00892.20 CDO68508.1 - 2.5e-16 60.1 31.6 5.2e-14 52.6 10.7 3.1 2 1 1 3 3 3 3 EamA-like transporter family Na_Ca_ex PF01699.24 CDO68508.1 - 0.00086 19.3 2.9 0.00086 19.3 2.9 3.3 3 1 0 4 4 4 1 Sodium/calcium exchanger protein E1-N PF14463.6 CDO68508.1 - 0.026 14.3 0.1 0.051 13.4 0.1 1.4 1 0 0 1 1 1 0 E1 N-terminal domain RseC_MucC PF04246.12 CDO68508.1 - 7 6.6 11.6 1.1 9.2 0.8 3.2 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Ion_trans PF00520.31 CDO68509.1 - 8.4e-104 346.1 84.6 3.6e-31 108.3 15.2 5.1 5 0 0 5 5 5 5 Ion transport protein PKD_channel PF08016.12 CDO68509.1 - 0.16 10.6 56.1 0.011 14.4 7.1 6.5 4 2 1 6 6 6 0 Polycystin cation channel Tubulin PF00091.25 CDO68510.1 - 8.3e-70 235.0 0.0 2e-69 233.7 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDO68510.1 - 7.9e-42 142.4 0.1 1.3e-41 141.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDO68510.1 - 1.7e-06 28.3 0.8 4e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CDO68510.1 - 0.0035 16.6 0.0 0.026 13.7 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Hydantoinase_A PF01968.18 CDO68511.1 - 7.5e-97 324.1 0.0 1.3e-96 323.3 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CDO68511.1 - 6.8e-59 198.5 0.1 3.5e-55 186.5 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region ENTH PF01417.20 CDO68512.1 - 6e-51 171.7 0.1 1.3e-50 170.7 0.1 1.6 1 0 0 1 1 1 1 ENTH domain AGH PF17558.2 CDO68512.1 - 0.13 12.5 0.5 0.26 11.5 0.5 1.5 1 0 0 1 1 1 0 Androgenic gland hormone PCI PF01399.27 CDO68513.1 - 2.5e-09 37.6 3.1 2.7e-07 31.0 0.0 3.4 3 0 0 3 3 3 2 PCI domain Cys_Met_Meta_PP PF01053.20 CDO68515.1 - 1.5e-120 402.3 0.0 8.9e-66 222.0 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CDO68515.1 - 1.1e-06 28.1 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CDO68515.1 - 1.1e-05 24.9 0.6 2.7e-05 23.7 0.2 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CDO68515.1 - 0.096 11.6 0.3 0.41 9.6 0.0 2.1 2 1 1 3 3 3 0 Aminotransferase class-V BRK PF07533.16 CDO68515.1 - 0.28 10.8 0.6 0.62 9.7 0.1 1.9 2 0 0 2 2 2 0 BRK domain zf-C2H2 PF00096.26 CDO68516.1 - 0.043 14.3 1.3 0.043 14.3 1.3 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 CDO68516.1 - 0.1 12.7 7.6 1.3 9.1 0.5 2.5 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 CDO68516.1 - 0.75 10.8 12.9 1.9 9.6 0.7 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDO68517.1 - 7e-10 38.8 12.9 8.8e-07 29.0 0.3 3.9 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO68517.1 - 3.6e-09 36.6 10.3 5.3e-09 36.1 0.4 4.2 4 0 0 4 4 4 1 Zinc-finger double domain FOXP-CC PF16159.5 CDO68517.1 - 1.2e-06 29.0 6.8 0.027 15.1 3.5 3.3 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CDO68517.1 - 0.00065 20.3 6.4 0.0098 16.7 0.3 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDO68517.1 - 0.0019 18.2 0.4 0.022 14.7 0.0 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 CDO68517.1 - 0.024 15.0 1.4 3.4 8.2 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CDO68517.1 - 0.16 11.8 0.2 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_ZIC PF18366.1 CDO68517.1 - 1.6 8.9 10.7 12 6.1 3.2 3.4 3 1 0 3 3 3 0 Zic proteins zinc finger domain Zap1_zf2 PF18217.1 CDO68517.1 - 2 8.5 10.2 0.19 11.7 2.5 2.8 3 0 0 3 3 3 0 Zap1 zinc finger 2 DUF3294 PF07957.11 CDO68519.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3294) Peptidase_M36 PF02128.15 CDO68520.1 - 5.9e-159 529.2 1.8 7.8e-159 528.8 1.8 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 CDO68520.1 - 3.9e-16 58.6 3.1 7.4e-16 57.7 3.1 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 CDO68520.1 - 0.081 12.8 0.3 0.2 11.5 0.1 1.7 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain LPAM_1 PF08139.12 CDO68520.1 - 0.95 10.1 2.1 1.9 9.2 2.1 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Cys_Met_Meta_PP PF01053.20 CDO68521.1 - 3.8e-137 456.9 0.0 4.3e-137 456.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CDO68521.1 - 2.1e-09 37.1 0.0 3.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CDO68521.1 - 2.4e-09 36.6 0.9 4.4e-08 32.5 0.1 2.6 3 0 0 3 3 3 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CDO68521.1 - 9.9e-09 35.0 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CDO68521.1 - 0.0089 15.3 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 CDO68521.1 - 0.0096 14.5 0.4 0.018 13.6 0.4 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase AP_endonuc_2 PF01261.24 CDO68521.1 - 0.13 11.6 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Cys_Met_Meta_PP PF01053.20 CDO68522.1 - 7e-142 472.5 0.0 8.1e-142 472.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CDO68522.1 - 1.6e-10 40.8 0.1 5.3e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CDO68522.1 - 1.1e-09 38.0 0.0 2.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CDO68522.1 - 2.4e-09 36.7 0.5 8.1e-09 34.9 0.1 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CDO68522.1 - 0.00011 21.6 0.0 0.00021 20.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 CDO68522.1 - 0.00026 19.7 0.0 0.00036 19.2 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 CDO68522.1 - 0.058 12.1 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDC-P PF02347.16 CDO68522.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein dsrm PF00035.26 CDO68523.1 - 0.028 15.1 0.1 23 5.8 0.0 3.6 3 0 0 3 3 3 0 Double-stranded RNA binding motif PhyH PF05721.13 CDO68524.1 - 1.9e-13 51.2 0.1 2.6e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ras PF00071.22 CDO68525.1 - 3.8e-50 169.7 0.0 4.4e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO68525.1 - 5.9e-30 103.9 0.0 8.8e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO68525.1 - 2.3e-12 46.7 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDO68525.1 - 9.2e-07 28.4 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDO68525.1 - 4.5e-06 26.7 0.0 8.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDO68525.1 - 0.0073 15.9 0.1 0.021 14.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CDO68525.1 - 0.026 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 CDO68525.1 - 0.027 13.6 0.6 1.6 7.8 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Septin PF00735.18 CDO68525.1 - 0.028 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 CDO68525.1 - 0.029 14.8 0.0 0.048 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 CDO68525.1 - 0.029 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CDO68525.1 - 0.14 12.1 0.1 0.48 10.3 0.1 1.8 1 1 1 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 CDO68525.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Na_Ca_ex PF01699.24 CDO68526.1 - 3.4e-15 56.3 15.5 9.4e-06 25.6 0.1 3.6 4 0 0 4 4 4 3 Sodium/calcium exchanger protein TMEM251 PF15190.6 CDO68526.1 - 0.02 14.8 0.3 0.081 12.9 0.3 2.0 1 0 0 1 1 1 0 Transmembrane protein 251 Na_Ca_ex PF01699.24 CDO68527.1 - 2.8e-15 56.6 23.2 6.1e-09 36.0 11.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Methyltransf_23 PF13489.6 CDO68528.1 - 8.7e-12 45.2 0.0 1.1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO68528.1 - 6.9e-07 29.8 0.0 1.9e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO68528.1 - 9.5e-06 26.2 0.0 2.1e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO68528.1 - 6e-05 23.7 0.0 0.00024 21.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO68528.1 - 0.00071 19.4 0.0 0.0037 17.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FBPase PF00316.20 CDO68528.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Acyltransferase PF01553.21 CDO68529.1 - 9.3e-12 44.7 0.0 1.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PAP2_3 PF14378.6 CDO68530.1 - 2.8e-23 82.6 18.5 2.8e-23 82.6 18.5 2.2 1 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CDO68530.1 - 8.7e-09 35.3 8.8 8.7e-09 35.3 8.8 2.2 3 0 0 3 3 3 1 PAP2 superfamily Questin_oxidase PF14027.6 CDO68531.1 - 1.5e-93 314.0 0.0 1.8e-93 313.8 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like Questin_oxidase PF14027.6 CDO68532.1 - 1.7e-91 307.3 0.0 2.1e-91 307.0 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like Mannosyl_trans2 PF04188.13 CDO68533.1 - 7.4e-46 157.4 17.1 2.8e-45 155.5 17.1 1.8 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) FA_hydroxylase PF04116.13 CDO68534.1 - 9.1e-23 81.1 20.0 9.1e-23 81.1 20.0 2.4 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily GST_N_3 PF13417.6 CDO68535.1 - 4.9e-12 46.1 0.0 1.1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO68535.1 - 1.2e-10 41.6 0.1 2.1e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO68535.1 - 0.00019 21.4 0.3 0.00019 21.4 0.3 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDO68535.1 - 0.004 17.4 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CMAS PF02353.20 CDO68537.1 - 2.4e-45 154.9 0.0 5.2e-24 85.0 0.0 2.2 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CDO68537.1 - 0.00042 21.0 0.0 0.0013 19.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO68537.1 - 0.001 19.6 0.0 0.0026 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Xan_ur_permease PF00860.20 CDO68538.1 - 6.3e-30 104.1 30.3 1.5e-17 63.4 13.6 2.5 3 0 0 3 3 3 2 Permease family MFS_MOT1 PF16983.5 CDO68538.1 - 0.011 16.1 5.4 0.011 16.1 5.4 2.9 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily RNA_pol_Rpc34 PF05158.12 CDO68539.1 - 4.9e-38 131.4 0.2 5.7e-38 131.1 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit CPSase_L_D2 PF02786.17 CDO68540.1 - 7e-116 385.1 0.1 1.1e-84 283.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CDO68540.1 - 2.2e-50 169.8 0.0 5.6e-50 168.5 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 CDO68540.1 - 1.9e-44 151.2 0.0 6.6e-44 149.5 0.0 2.0 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 CDO68540.1 - 5.3e-43 147.0 0.0 3.5e-42 144.3 0.0 2.3 3 0 0 3 3 3 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CDO68540.1 - 2.3e-42 144.2 0.1 4.9e-42 143.1 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CDO68540.1 - 1.5e-30 106.3 0.0 4.9e-30 104.7 0.0 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 CDO68540.1 - 8e-20 71.2 0.2 1.2e-09 38.0 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 CDO68540.1 - 3.1e-18 65.8 0.0 1.3e-17 63.8 0.0 2.2 2 0 0 2 2 1 1 MGS-like domain ATP-grasp PF02222.22 CDO68540.1 - 2.6e-17 62.9 0.0 3.1e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CDO68540.1 - 2.4e-09 37.0 0.1 0.0014 18.4 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 CDO68540.1 - 2.1e-06 27.9 0.2 0.029 14.4 0.0 2.7 3 0 0 3 3 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 CDO68540.1 - 2.3e-05 24.3 0.2 0.0033 17.2 0.0 3.0 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 CDO68540.1 - 0.0017 18.2 0.0 0.53 10.1 0.0 4.2 5 0 0 5 5 5 1 DJ-1/PfpI family GARS_A PF01071.19 CDO68540.1 - 0.031 14.0 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 CDO68540.1 - 0.063 12.7 0.0 1.5 8.2 0.1 2.3 2 0 0 2 2 2 0 ATP-grasp domain SLATT_fungal PF18142.1 CDO68541.1 - 5.5e-38 129.6 0.4 8.9e-38 129.0 0.4 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain MFS_1 PF07690.16 CDO68542.1 - 2.9e-40 138.3 55.9 4.3e-37 127.9 58.0 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 CDO68542.1 - 9.5 6.0 14.9 0.12 12.2 2.1 3.2 3 2 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) zf-MYND PF01753.18 CDO68543.1 - 1.6e-09 37.7 12.2 2.6e-09 37.0 12.2 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CDO68543.1 - 0.1 12.9 10.8 0.19 12.1 10.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DnaJ-X PF14308.6 CDO68544.1 - 1.4e-56 191.3 2.9 1.4e-56 191.3 2.9 1.7 2 0 0 2 2 2 1 X-domain of DnaJ-containing tRNA-synt_1b PF00579.25 CDO68544.1 - 2.2e-42 145.4 0.1 6.2e-36 124.2 0.0 3.6 3 1 0 3 3 3 2 tRNA synthetases class I (W and Y) DnaJ PF00226.31 CDO68544.1 - 4.5e-13 49.1 0.5 4.5e-13 49.1 0.5 3.1 3 0 0 3 3 3 1 DnaJ domain FtsJ PF01728.19 CDO68545.1 - 5.1e-28 98.4 0.0 8.8e-28 97.6 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase CENP-T_C PF15511.6 CDO68546.1 - 7.3e-07 29.3 0.0 1.1e-06 28.7 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CDO68546.1 - 8.1e-05 22.7 0.2 0.00017 21.7 0.1 1.6 1 1 1 2 2 2 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CDO68546.1 - 0.00022 21.6 0.0 0.00033 21.0 0.0 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CDO68546.1 - 0.0016 18.7 0.1 0.0033 17.7 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDO68546.1 - 0.0032 17.8 0.1 0.0039 17.6 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CDO68546.1 - 0.06 13.4 0.5 0.83 9.7 0.0 2.1 2 0 0 2 2 2 0 Bromodomain associated TFIID-31kDa PF02291.15 CDO68546.1 - 0.098 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIIIC_sub6 PF10419.9 CDO68547.1 - 1.9e-16 59.7 0.0 4.1e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Pns11_12 PF17464.2 CDO68547.1 - 0.026 14.2 2.2 0.036 13.8 2.2 1.2 1 0 0 1 1 1 0 Non-structural protein 11 and 12 MFS_1 PF07690.16 CDO68548.1 - 1.6e-31 109.6 45.4 1.6e-31 109.6 45.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 CDO68548.1 - 1.6e-07 31.0 5.3 1.6e-07 31.0 5.3 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 CDO68548.1 - 1.8e-07 30.4 11.6 1.8e-07 30.4 11.6 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter S10_plectin PF03501.15 CDO68548.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain Hydrophobin PF01185.18 CDO68549.1 - 0.49 11.0 5.6 1.3 9.7 5.7 1.6 1 1 1 2 2 2 0 Fungal hydrophobin PT PF04886.12 CDO68549.1 - 0.85 9.2 12.6 1.6 8.4 1.4 3.3 2 1 1 3 3 3 0 PT repeat PT PF04886.12 CDO68550.1 - 0.18 11.4 18.6 0.039 13.5 3.0 4.3 2 1 2 4 4 4 0 PT repeat p450 PF00067.22 CDO68551.1 - 1.4e-52 179.0 0.0 2.5e-45 155.1 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 adh_short PF00106.25 CDO68552.1 - 4.6e-21 75.2 0.0 6.4e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO68552.1 - 4.9e-16 59.0 0.0 6.4e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO68552.1 - 0.00059 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO68552.1 - 0.0023 17.4 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CDO68552.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H-binding Hydrophobin PF01185.18 CDO68554.1 - 1.3e-23 83.4 9.0 2.1e-23 82.8 9.0 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 CDO68555.1 - 4.3e-09 36.9 0.8 6.9e-09 36.2 0.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 CDO68556.1 - 1e-17 64.5 8.1 1.3e-17 64.2 8.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Septin PF00735.18 CDO68557.1 - 3.8e-112 374.2 0.3 5.1e-112 373.7 0.3 1.2 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 CDO68557.1 - 1.4e-07 31.6 0.1 2.9e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CDO68557.1 - 3.4e-07 30.3 0.0 7.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDO68557.1 - 1.1e-06 28.3 0.5 0.00042 19.9 0.0 2.6 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CDO68557.1 - 0.00028 20.3 0.0 0.00053 19.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 CDO68557.1 - 0.00044 20.4 0.0 0.00096 19.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CDO68557.1 - 0.00091 19.7 0.4 0.0032 17.8 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDO68557.1 - 0.0014 18.9 1.3 0.0062 16.8 0.1 2.5 2 2 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CDO68557.1 - 0.0018 18.8 0.2 0.013 16.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.9 CDO68557.1 - 0.0025 17.6 0.2 0.15 11.8 0.1 2.5 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CDO68557.1 - 0.008 15.7 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Ras PF00071.22 CDO68557.1 - 0.011 15.4 0.1 0.032 13.8 0.1 1.8 1 1 0 1 1 1 0 Ras family AAA_24 PF13479.6 CDO68557.1 - 0.063 13.0 1.9 0.067 12.9 0.3 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 CDO68557.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.23 CDO68557.1 - 0.072 13.1 6.7 1.4 8.9 0.1 2.9 2 1 1 3 3 3 0 Dynamin family NB-ARC PF00931.22 CDO68557.1 - 0.073 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 CDO68557.1 - 0.11 12.1 0.6 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CDO68557.1 - 0.13 12.3 0.4 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CDO68557.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CDO68557.1 - 0.19 11.3 0.3 1.1 8.8 0.3 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Frankia_peptide PF14407.6 CDO68559.1 - 0.032 14.2 0.0 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. HA2 PF04408.23 CDO68562.1 - 1.2e-24 86.7 0.0 2.5e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDO68562.1 - 4.7e-22 78.1 0.0 2.9e-21 75.6 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CDO68562.1 - 5.4e-07 29.5 0.3 3.2e-06 27.0 0.3 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 CDO68562.1 - 0.00039 20.1 0.2 0.0027 17.4 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CDO68562.1 - 0.0013 19.0 0.4 0.32 11.3 0.0 2.9 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 CDO68562.1 - 0.0047 17.3 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDO68562.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 CDO68562.1 - 0.048 13.7 0.0 6.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CDO68562.1 - 0.12 11.8 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 CDO68562.1 - 0.16 12.5 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 CDO68562.1 - 0.17 11.3 0.1 0.67 9.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Proteasome PF00227.26 CDO68563.1 - 6.8e-20 71.4 0.1 6e-19 68.3 0.1 2.0 1 1 0 1 1 1 1 Proteasome subunit RVT_2 PF07727.14 CDO68565.1 - 5.2e-80 268.6 0.1 7.2e-80 268.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4939 PF16297.5 CDO68565.1 - 6.4e-07 29.2 0.1 2.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) RNA_polI_A34 PF08208.11 CDO68565.1 - 1.1 9.3 5.4 3.1 7.9 5.4 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDE_3 PF13358.6 CDO68568.1 - 2.1e-25 89.2 0.1 5.8e-25 87.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDO68568.1 - 1.7e-06 28.5 1.2 3.2e-06 27.7 0.4 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDO68568.1 - 4.3e-05 23.7 0.0 9.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.6 CDO68568.1 - 0.0002 20.9 0.2 0.0006 19.4 0.2 1.8 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.26 CDO68568.1 - 0.0064 16.7 0.0 0.029 14.5 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain PLU-1 PF08429.11 CDO68568.1 - 0.14 11.3 0.0 7.7 5.6 0.0 2.1 2 0 0 2 2 2 0 PLU-1-like protein AP3D1 PF06375.11 CDO68569.1 - 0.0062 16.8 2.5 0.015 15.5 2.5 1.7 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 zf-CCHC_6 PF15288.6 CDO68570.1 - 0.00063 19.5 1.7 0.0016 18.3 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle RP-C_C PF11800.8 CDO68577.1 - 0.079 13.1 12.4 0.52 10.4 7.2 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Coilin_N PF15862.5 CDO68577.1 - 0.1 12.4 8.3 0.22 11.3 8.3 1.5 1 0 0 1 1 1 0 Coilin N-terminus MRNIP PF15749.5 CDO68577.1 - 0.44 11.3 5.7 0.35 11.6 1.7 2.0 2 0 0 2 2 2 0 MRN-interacting protein Presenilin PF01080.17 CDO68577.1 - 1.2 7.8 6.2 1.2 7.8 6.2 1.2 1 0 0 1 1 1 0 Presenilin GRP PF07172.11 CDO68577.1 - 3.9 8.2 19.2 0.56 10.9 2.8 2.7 2 1 0 2 2 2 0 Glycine rich protein family CDC45 PF02724.14 CDO68577.1 - 7 4.8 12.6 8.1 4.6 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Integrase_H2C2 PF17921.1 CDO68578.1 - 5e-17 61.8 0.3 1.4e-16 60.3 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO68578.1 - 4.4e-15 55.9 0.0 8.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDO68578.1 - 5.3e-07 29.7 0.1 1e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 CDO68578.1 - 1.3e-05 25.0 0.2 2.5e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2550 PF10739.9 CDO68579.1 - 0.17 11.9 0.8 0.34 10.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) RVT_1 PF00078.27 CDO68580.1 - 1.2e-58 198.3 0.1 6e-32 110.9 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDO68580.1 - 6.9e-37 125.9 0.0 1.3e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO68580.1 - 5.3e-33 113.0 0.0 1.2e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_2 PF07727.14 CDO68580.1 - 0.0035 17.0 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF503 PF04456.12 CDO68580.1 - 0.0085 15.9 2.7 2.7 7.9 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF503) DDE_Tnp_4 PF13359.6 CDO68580.1 - 0.051 13.2 0.3 8.6 6.0 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease DUF1474 PF07342.11 CDO68580.1 - 0.09 13.3 0.0 10 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Retrotrans_gag PF03732.17 CDO68581.1 - 1.8e-10 40.9 0.0 3.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO68581.1 - 5.8e-09 35.8 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 CDO68582.1 - 9.3e-13 48.3 0.1 2.9e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO68582.1 - 5e-09 36.0 0.0 9.1e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Smg4_UPF3 PF03467.15 CDO68583.1 - 3.7e-54 183.4 0.8 3.7e-54 183.4 0.8 3.0 4 0 0 4 4 4 1 Smg-4/UPF3 family DUF4121 PF13497.6 CDO68583.1 - 0.14 11.3 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) COesterase PF00135.28 CDO68585.1 - 5.5e-90 302.7 0.1 3.5e-89 300.0 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDO68585.1 - 2.5e-12 47.1 1.6 7.6e-12 45.5 1.4 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDO68585.1 - 0.0022 17.5 0.1 0.0042 16.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 CDO68585.1 - 0.0051 16.5 0.8 0.014 15.1 0.8 1.5 1 1 0 1 1 1 1 Putative esterase Say1_Mug180 PF10340.9 CDO68585.1 - 0.094 11.6 0.1 1.1 8.1 0.1 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase tRNA-synt_2b PF00587.25 CDO68587.1 - 3.4e-35 121.6 0.0 6.4e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CDO68587.1 - 8.9e-18 64.2 0.2 2.2e-17 63.0 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.21 CDO68587.1 - 2.1e-16 59.7 0.0 4.1e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 CDO68587.1 - 4.8e-12 45.8 0.0 8.9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MBOAT_2 PF13813.6 CDO68588.1 - 6.2e-16 58.4 1.5 6.2e-16 58.4 1.5 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family YiaAB PF05360.14 CDO68588.1 - 0.74 10.1 5.0 0.96 9.7 0.2 2.7 2 1 0 2 2 2 0 yiaA/B two helix domain MBOAT_2 PF13813.6 CDO68589.1 - 2.4e-20 72.6 7.6 5.9e-20 71.3 7.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.6 CDO68590.1 - 2.7e-18 66.0 8.2 3.8e-18 65.5 5.8 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Pyridoxal_deC PF00282.19 CDO68591.1 - 5.5e-86 288.6 0.0 2.7e-85 286.4 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CDO68591.1 - 0.0054 15.7 0.0 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CDO68591.1 - 0.01 15.1 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II OKR_DC_1 PF01276.20 CDO68591.1 - 0.012 14.4 0.0 0.024 13.4 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain MFS_1 PF07690.16 CDO68592.1 - 1.1e-24 87.0 35.9 1.1e-24 87.0 35.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 CDO68593.1 - 2.2e-33 115.8 0.0 4.9e-33 114.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDO68593.1 - 9.8e-07 29.2 0.1 0.048 14.2 0.0 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDO68593.1 - 0.085 12.1 0.1 2.2 7.4 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase WH1 PF00568.23 CDO68594.1 - 4.4e-11 42.7 0.0 8.1e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 WH1 domain PBD PF00786.28 CDO68594.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 P21-Rho-binding domain Methyltr_RsmB-F PF01189.17 CDO68595.1 - 7.4e-33 113.9 0.0 1.2e-16 61.0 0.0 3.6 2 2 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CDO68595.1 - 0.031 14.4 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase SNF5 PF04855.12 CDO68596.1 - 1.8e-68 230.8 0.9 1.8e-68 230.8 0.9 2.4 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 CDO68596.1 - 3.8 7.2 6.0 8.1 6.2 6.0 1.6 1 0 0 1 1 1 0 GATA zinc finger NAD_binding_6 PF08030.12 CDO68597.1 - 7.8e-38 130.0 0.0 1.5e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CDO68597.1 - 7e-23 80.8 0.0 1.5e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CDO68597.1 - 1.8e-19 70.1 9.2 1.8e-19 70.1 9.2 2.7 2 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 CDO68597.1 - 0.04 14.3 0.0 0.082 13.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Pam17 PF08566.10 CDO68597.1 - 0.083 12.7 0.3 0.24 11.2 0.3 1.7 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Glyco_hydro_28 PF00295.17 CDO68598.1 - 7.4e-36 123.8 0.0 9.7e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CDO68598.1 - 0.25 11.2 2.6 0.44 10.4 0.7 2.4 2 1 0 2 2 2 0 Right handed beta helix region HTH_23 PF13384.6 CDO68599.1 - 0.0044 16.8 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain ABC_tran PF00005.27 CDO68600.1 - 6.2e-51 172.5 0.0 1.9e-30 106.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CDO68600.1 - 1.3e-48 166.0 24.0 2e-28 99.8 4.0 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 CDO68600.1 - 4.2e-07 29.6 0.0 0.0075 15.7 0.3 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 CDO68600.1 - 1.1e-06 28.0 6.0 0.00036 19.7 0.1 3.2 2 1 1 3 3 3 2 Type II/IV secretion system protein AAA_21 PF13304.6 CDO68600.1 - 9.8e-06 25.6 2.0 0.83 9.4 0.2 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDO68600.1 - 1.1e-05 25.1 0.5 0.21 11.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CDO68600.1 - 1.4e-05 25.6 2.3 0.099 13.0 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CDO68600.1 - 7.1e-05 22.5 0.8 0.13 11.9 0.2 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CDO68600.1 - 0.00014 22.4 0.1 0.029 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDO68600.1 - 0.0011 19.2 1.9 6.2 7.1 0.1 3.4 2 1 1 3 3 3 1 AAA domain DUF87 PF01935.17 CDO68600.1 - 0.005 17.0 0.2 0.017 15.2 0.2 1.9 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_7 PF12775.7 CDO68600.1 - 0.021 14.4 0.3 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CDO68600.1 - 0.029 14.5 0.3 0.66 10.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDO68600.1 - 0.042 13.9 0.0 4.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family DUF809 PF05663.11 CDO68600.1 - 0.042 14.0 0.3 0.16 12.1 0.1 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF809) RseC_MucC PF04246.12 CDO68600.1 - 0.051 13.5 0.2 0.19 11.7 0.2 1.9 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC AAA_33 PF13671.6 CDO68600.1 - 0.076 13.2 0.1 11 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CDO68600.1 - 0.57 9.7 1.8 6.7 6.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 CDO68601.1 - 1.5e-50 171.3 0.0 9.5e-30 103.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CDO68601.1 - 9.5e-50 169.8 21.3 1.9e-28 99.9 3.2 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region T2SSE PF00437.20 CDO68601.1 - 4.4e-08 32.5 0.6 0.00025 20.2 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.19 CDO68601.1 - 1.4e-06 27.9 0.9 0.047 13.1 0.1 4.5 3 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 CDO68601.1 - 4.5e-06 26.4 0.4 0.047 13.3 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CDO68601.1 - 6.4e-06 25.8 0.5 0.16 11.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CDO68601.1 - 1.5e-05 25.5 0.8 0.17 12.3 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CDO68601.1 - 2.6e-05 24.2 4.1 0.81 9.4 0.2 4.3 2 2 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDO68601.1 - 0.00012 22.7 0.2 0.031 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDO68601.1 - 0.0013 19.1 0.5 5.8 7.2 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 CDO68601.1 - 0.0058 16.2 0.4 1.6 8.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 CDO68601.1 - 0.013 15.6 0.3 0.039 14.1 0.3 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 CDO68601.1 - 0.018 14.0 1.1 0.11 11.4 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 CDO68601.1 - 0.022 14.8 1.5 0.36 10.9 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CDO68601.1 - 0.023 14.9 0.2 4.9 7.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 CDO68601.1 - 0.042 13.8 0.8 1.2 9.1 0.1 3.0 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 CDO68601.1 - 0.059 13.4 0.8 3.7 7.6 0.0 2.6 3 0 0 3 3 2 0 Dynamin family Zeta_toxin PF06414.12 CDO68601.1 - 0.061 12.6 0.1 9.4 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 CDO68601.1 - 0.11 12.3 0.0 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CDO68601.1 - 0.15 11.9 0.2 8.9 6.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase bZIP_2 PF07716.15 CDO68602.1 - 0.00024 21.1 15.8 0.00098 19.2 2.1 2.7 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 CDO68602.1 - 0.00028 20.9 12.1 0.0018 18.3 2.6 2.3 2 0 0 2 2 2 2 bZIP transcription factor NAM-associated PF14303.6 CDO68602.1 - 0.0009 20.0 3.9 0.0009 20.0 3.9 2.1 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain CSTF_C PF14304.6 CDO68602.1 - 0.0068 16.0 1.7 0.022 14.3 1.7 1.9 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal TMCO5 PF14992.6 CDO68602.1 - 0.031 13.8 0.5 0.047 13.3 0.5 1.2 1 0 0 1 1 1 0 TMCO5 family MerR_2 PF13591.6 CDO68602.1 - 0.06 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein Cnn_1N PF07989.11 CDO68602.1 - 0.27 11.4 4.2 0.49 10.6 4.0 1.5 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 SIKE PF05769.11 CDO68602.1 - 0.34 10.8 4.7 0.77 9.7 4.7 1.5 1 1 0 1 1 1 0 SIKE family Fungal_TACC PF12709.7 CDO68602.1 - 0.83 10.1 5.0 0.35 11.3 2.2 1.8 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins PKcGMP_CC PF16808.5 CDO68602.1 - 2 8.3 10.5 4 7.4 10.5 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Phage_Nu1 PF07471.12 CDO68602.1 - 4 7.2 6.0 18 5.0 1.1 2.1 1 1 1 2 2 2 0 Phage DNA packaging protein Nu1 TAL_FSA PF00923.19 CDO68603.1 - 1.1e-19 70.8 0.1 2.4e-19 69.7 0.0 1.5 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Hydrolase_like PF13242.6 CDO68604.1 - 3.2e-19 68.8 0.0 6.3e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 CDO68604.1 - 4.7e-15 55.5 0.6 1.6e-08 34.5 0.1 2.7 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDO68604.1 - 2.2e-10 41.2 0.0 6.3e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDO68604.1 - 2.5e-05 24.5 0.0 0.00062 19.9 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CDO68604.1 - 0.071 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Ribosomal_L34e PF01199.18 CDO68605.1 - 2.7e-44 149.4 2.5 3.7e-44 148.9 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 CDO68605.1 - 0.062 13.2 4.1 2.3 8.2 0.4 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Nop53 PF07767.11 CDO68606.1 - 1.3e-76 258.5 30.5 3.1e-74 250.8 24.7 2.5 2 1 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) BOP1NT PF08145.12 CDO68606.1 - 9.6e-07 29.0 0.8 9.6e-07 29.0 0.8 1.8 2 0 0 2 2 2 1 BOP1NT (NUC169) domain Usp PF00582.26 CDO68607.1 - 1.4e-14 54.8 0.0 2e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family RCC1 PF00415.18 CDO68609.1 - 1.1e-27 96.4 4.1 7.9e-07 29.6 0.0 4.4 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDO68609.1 - 5.5e-17 61.1 21.7 1.4e-08 34.3 0.5 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat MFS_1 PF07690.16 CDO68611.1 - 7.9e-33 113.8 35.1 8.9e-33 113.7 33.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FHA PF00498.26 CDO68612.1 - 9.5e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDO68612.1 - 0.0011 19.2 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF5631 PF18645.1 CDO68613.1 - 0.1 13.0 0.0 0.33 11.4 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5631) Alginate_lyase PF05426.12 CDO68614.1 - 2.1e-68 230.8 5.1 2e-67 227.6 4.0 2.0 2 0 0 2 2 2 2 Alginate lyase Glyco_hydro_28 PF00295.17 CDO68615.1 - 4.8e-59 200.0 11.4 6.1e-59 199.7 11.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Fungal_trans PF04082.18 CDO68616.1 - 2e-11 43.4 0.0 3.8e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CDO68616.1 - 2e-06 27.8 9.4 3.6e-06 27.0 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 CDO68617.1 - 8.8e-20 70.6 0.0 2.3e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CDO68617.1 - 1.3e-17 64.1 0.0 6.3e-14 51.9 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDO68617.1 - 1.3e-12 47.6 0.0 2.3e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDO68617.1 - 9.8e-10 38.1 0.0 4.9e-08 32.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 CDO68617.1 - 0.0027 17.8 0.3 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 CDO68617.1 - 0.019 15.5 0.1 0.36 11.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO68617.1 - 0.035 14.3 0.2 0.55 10.5 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 CDO68617.1 - 0.088 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 CDO68617.1 - 0.09 11.8 1.1 1.1 8.2 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 CDO68617.1 - 0.13 12.2 0.0 18 5.3 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Transp_cyt_pur PF02133.15 CDO68618.1 - 4.8e-18 65.2 32.2 1.2e-09 37.5 28.0 2.8 2 1 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Pyr_redox_3 PF13738.6 CDO68618.1 - 0.025 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S24 PF00717.23 CDO68619.1 - 1.2e-07 31.5 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HLH PF00010.26 CDO68620.1 - 1e-07 31.8 0.5 1.9e-07 30.9 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PBP1_TM PF14812.6 CDO68620.1 - 6.4 7.2 10.0 1.5 9.2 1.2 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gpi1 PF05024.15 CDO68621.1 - 6.4e-66 222.0 6.1 9.7e-66 221.4 6.1 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) AMP-binding PF00501.28 CDO68622.1 - 2.8e-76 256.8 0.2 8.6e-55 186.0 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CDO68622.1 - 3e-15 57.0 0.2 8.3e-15 55.5 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CCDC92 PF14916.6 CDO68624.1 - 0.023 14.4 0.2 0.1 12.4 0.2 2.1 1 0 0 1 1 1 0 Coiled-coil domain of unknown function DUF1664 PF07889.12 CDO68624.1 - 0.028 14.4 9.4 2.4 8.2 0.0 4.8 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) ApoB100_C PF12491.8 CDO68624.1 - 0.044 13.7 0.3 2.2 8.3 0.0 3.4 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal Lectin_N PF03954.14 CDO68624.1 - 0.046 13.5 3.2 0.18 11.5 0.2 3.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF4618 PF15397.6 CDO68624.1 - 1.9 7.9 18.0 0.067 12.6 2.3 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) HALZ PF02183.18 CDO68624.1 - 5.1 7.4 8.1 12 6.2 0.1 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.11 CDO68624.1 - 6.3 7.4 14.5 18 6.0 1.0 5.0 4 2 1 5 5 5 0 Syntaxin 6, N-terminal UCH PF00443.29 CDO68625.1 - 2.2e-45 155.2 0.0 3.1e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDO68625.1 - 1.4e-09 38.1 0.0 1.6e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Fibrillarin PF01269.17 CDO68626.1 - 2.1e-104 347.6 0.0 3.1e-104 347.0 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin PMT PF02366.18 CDO68626.1 - 5.6e-81 271.7 18.8 1.1e-80 270.8 18.8 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CDO68626.1 - 3.1e-59 199.9 8.2 3.1e-59 199.9 8.2 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CDO68626.1 - 1e-27 97.2 0.0 1.7e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 MIR domain GCD14 PF08704.10 CDO68626.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 CDO68626.1 - 0.066 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MFS_1 PF07690.16 CDO68627.1 - 3.1e-16 59.3 44.2 3.1e-16 59.3 44.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 CDO68627.1 - 1.8 8.6 0.0 1.8 8.6 0.0 3.7 4 1 1 5 5 5 0 Bacteriophage P21 holin S F-box-like PF12937.7 CDO68628.1 - 0.00033 20.5 2.2 0.00082 19.2 2.2 1.7 1 0 0 1 1 1 1 F-box-like MitMem_reg PF13012.6 CDO68630.1 - 1.6e-34 118.7 1.4 2.8e-34 117.9 1.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CDO68630.1 - 1.9e-24 85.9 0.0 4.5e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Imm3 PF14425.6 CDO68630.1 - 0.025 14.6 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Immunity protein Imm3 COX4 PF02936.14 CDO68631.1 - 8e-37 126.3 0.0 1e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV zf-CCHC PF00098.23 CDO68632.1 - 1.2e-51 170.5 63.4 8.3e-09 35.1 2.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CDO68632.1 - 1.9e-11 43.5 44.6 0.0084 15.8 1.1 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 CDO68632.1 - 7.8e-09 35.4 42.0 0.016 15.2 1.7 7.2 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.6 CDO68632.1 - 0.0037 17.1 53.6 0.034 14.0 1.8 7.3 6 1 1 7 7 7 5 Zinc knuckle zf-CCHC_5 PF14787.6 CDO68632.1 - 0.055 13.2 0.6 0.055 13.2 0.6 6.1 5 2 2 7 7 7 0 GAG-polyprotein viral zinc-finger ATP-synt_Eps PF04627.13 CDO68633.1 - 6.5e-22 77.3 2.8 8.7e-22 76.9 2.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PikAIV_N PF18605.1 CDO68633.1 - 0.072 12.7 3.6 0.11 12.0 3.6 1.3 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Ras PF00071.22 CDO68634.1 - 8.3e-29 100.3 0.0 2.9e-18 66.0 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 CDO68634.1 - 6.1e-12 45.8 0.0 3.7e-07 30.4 0.0 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CDO68634.1 - 0.055 13.5 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDO68634.1 - 0.12 12.3 0.0 4 7.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Adeno_IVa2 PF02456.15 CDO68634.1 - 0.15 10.8 0.0 2.2 7.0 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein DEAD PF00270.29 CDO68635.1 - 1e-45 155.6 0.5 1e-45 155.6 0.5 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO68635.1 - 1.1e-32 112.7 0.4 1.7e-31 108.8 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO68635.1 - 5.6e-06 26.5 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CDO68635.1 - 0.00032 21.0 1.3 0.0084 16.5 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDO68635.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CDO68635.1 - 0.014 14.9 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain CMS1 PF14617.6 CDO68635.1 - 0.043 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.25 CDO68635.1 - 0.045 13.1 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.14 CDO68635.1 - 0.064 13.2 0.1 0.33 10.9 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 CDO68635.1 - 0.16 12.2 0.3 0.64 10.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain DUF382 PF04037.13 CDO68636.1 - 3.7e-60 201.7 0.5 3.7e-60 201.7 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 CDO68636.1 - 1.8e-17 62.9 4.9 3.8e-17 61.9 4.9 1.6 1 0 0 1 1 1 1 PSP HMGL-like PF00682.19 CDO68637.1 - 1.6e-71 241.0 0.0 2.3e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 CDO68637.1 - 5.8e-47 158.9 0.1 2.5e-22 79.2 0.0 2.5 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain Metallophos PF00149.28 CDO68638.1 - 1.3e-08 35.6 0.0 3e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDO68638.1 - 0.047 13.9 0.0 0.19 11.9 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain tRNA-synt_1c PF00749.21 CDO68639.1 - 7.6e-106 353.5 0.0 1.5e-105 352.6 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CDO68639.1 - 2.3e-33 115.5 0.9 4.3e-33 114.6 0.9 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 CDO68639.1 - 3.3e-07 30.4 0.0 8.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO68639.1 - 1.5e-05 24.9 0.3 3.7e-05 23.6 0.3 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO68639.1 - 0.00044 20.4 0.0 0.003 17.7 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DNA_pol_D_N PF18018.1 CDO68639.1 - 0.076 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Retrotran_gag_2 PF14223.6 CDO68640.1 - 2.1e-05 24.2 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 CDO68640.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type ADH_zinc_N PF00107.26 CDO68641.1 - 1.8e-10 40.9 0.1 5.5e-10 39.3 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO68641.1 - 3.3e-05 23.7 0.1 0.0002 21.2 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDO68641.1 - 7.4e-05 23.8 0.0 0.00015 22.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2496 PF10689.9 CDO68641.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2496) F-box-like PF12937.7 CDO68642.1 - 0.005 16.7 0.1 0.032 14.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like Sec10 PF07393.11 CDO68647.1 - 5.8e-133 444.8 0.0 1.5e-132 443.4 0.0 1.5 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 CDO68647.1 - 3.8e-05 23.4 0.1 0.00011 22.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO68647.1 - 0.0002 21.2 0.5 0.00057 19.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like EBP50_C PF09007.11 CDO68647.1 - 1.5 9.8 5.4 0.25 12.4 0.9 1.9 2 0 0 2 2 2 0 EBP50, C-terminal ABC1 PF03109.16 CDO68648.1 - 1e-26 93.4 0.1 1.8e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 CDO68648.1 - 0.0018 18.3 1.5 0.049 13.5 1.4 2.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family PhoLip_ATPase_C PF16212.5 CDO68649.1 - 3e-80 269.6 24.5 3e-80 269.6 24.5 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDO68649.1 - 1e-25 89.2 5.3 3.2e-25 87.6 5.3 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal GIT_SHD PF08518.11 CDO68649.1 - 3.3e-25 87.4 6.0 4.2e-13 48.7 2.5 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Cation_ATPase PF13246.6 CDO68649.1 - 1.8e-11 44.0 0.0 1.5e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CDO68649.1 - 1.4e-07 31.2 0.0 4.1e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CDO68649.1 - 3.7e-06 27.4 1.2 0.17 12.1 0.0 4.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDO68649.1 - 0.0058 16.4 0.1 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase V_ATPase_I PF01496.19 CDO68649.1 - 0.21 9.5 4.6 0.32 8.9 3.7 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3037 PF11236.8 CDO68649.1 - 1.1 9.7 5.9 7.1 7.1 2.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Golgin_A5 PF09787.9 CDO68649.1 - 1.2 8.6 28.0 0.24 10.9 21.5 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 FAM76 PF16046.5 CDO68649.1 - 5.9 6.2 12.4 2.8 7.2 9.0 2.1 1 1 1 2 2 2 0 FAM76 protein Aldo_ket_red PF00248.21 CDO68650.1 - 2.8e-53 181.0 0.0 1e-52 179.2 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family COesterase PF00135.28 CDO68651.1 - 6.8e-05 21.9 0.0 9.1e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family MFS_1 PF07690.16 CDO68655.1 - 1.4e-14 53.8 11.5 1.9e-14 53.3 11.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CDO68655.1 - 0.15 10.9 8.5 0.28 10.0 8.5 1.4 1 1 0 1 1 1 0 MFS_1 like family NOA36 PF06524.12 CDO68655.1 - 2.4 7.4 5.3 3.4 6.9 5.3 1.1 1 0 0 1 1 1 0 NOA36 protein zf-C2H2_4 PF13894.6 CDO68656.1 - 0.0039 17.9 0.6 0.0086 16.8 0.6 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CDO68656.1 - 0.015 15.7 0.5 0.033 14.6 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Sugar_tr PF00083.24 CDO68657.1 - 2.3e-77 260.8 20.9 4e-77 260.0 17.6 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDO68657.1 - 6.1e-15 55.0 47.5 1.1e-13 50.8 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG11 PF10377.9 CDO68658.1 - 1.2e-31 109.4 0.6 3.4e-31 108.0 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein 11 GAS PF13851.6 CDO68658.1 - 0.0013 18.1 12.3 0.0013 18.1 12.3 5.3 2 2 4 6 6 6 2 Growth-arrest specific micro-tubule binding THP2 PF09432.10 CDO68658.1 - 0.65 10.0 3.8 7.6 6.6 1.4 3.5 3 0 0 3 3 3 0 Tho complex subunit THP2 adh_short PF00106.25 CDO68658.1 - 3.9 6.9 5.4 2.4 7.6 0.1 2.5 2 0 0 2 2 2 0 short chain dehydrogenase DUF4419 PF14388.6 CDO68660.1 - 1.4e-109 366.2 0.0 1.6e-109 366.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) PapB PF03333.13 CDO68660.1 - 0.22 11.6 0.3 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Adhesin biosynthesis transcription regulatory protein FlaC_arch PF05377.11 CDO68661.1 - 3.8e-06 27.2 6.8 0.00034 20.9 1.6 3.2 2 1 0 3 3 2 1 Flagella accessory protein C (FlaC) XhlA PF10779.9 CDO68661.1 - 4.4e-06 26.8 1.9 4.4e-06 26.8 1.9 2.8 3 0 0 3 3 2 1 Haemolysin XhlA MscS_porin PF12795.7 CDO68661.1 - 2.3e-05 24.1 0.5 2.3e-05 24.1 0.5 2.2 2 0 0 2 2 1 1 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.12 CDO68661.1 - 0.00011 22.2 8.4 0.0007 19.7 8.4 2.1 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 CDO68661.1 - 0.00015 22.2 13.7 0.034 14.6 0.4 3.1 2 1 1 3 3 3 2 Protein of unknown function DUF16 CREPT PF16566.5 CDO68661.1 - 0.002 18.3 1.3 0.002 18.3 1.3 2.5 2 1 1 3 3 3 1 Cell-cycle alteration and expression-elevated protein in tumour EzrA PF06160.12 CDO68661.1 - 0.0023 16.2 1.4 0.0046 15.2 0.4 1.9 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Prefoldin_2 PF01920.20 CDO68661.1 - 0.0032 17.4 0.8 0.0032 17.4 0.8 3.2 2 1 0 3 3 2 1 Prefoldin subunit Med4 PF10018.9 CDO68661.1 - 0.0038 16.9 8.4 0.2 11.3 0.0 3.1 3 0 0 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 Snapin_Pallidin PF14712.6 CDO68661.1 - 0.0053 17.2 2.6 0.0053 17.2 2.6 2.7 2 1 1 3 3 2 1 Snapin/Pallidin ABC_tran_CTD PF16326.5 CDO68661.1 - 0.0064 16.7 0.1 0.0064 16.7 0.1 3.1 3 0 0 3 3 2 1 ABC transporter C-terminal domain ING PF12998.7 CDO68661.1 - 0.0077 16.8 2.8 0.035 14.7 0.2 2.4 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding FAM76 PF16046.5 CDO68661.1 - 0.0077 15.6 5.2 0.0093 15.3 0.5 2.0 2 0 0 2 2 2 1 FAM76 protein DUF4407 PF14362.6 CDO68661.1 - 0.018 14.4 4.1 0.09 12.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 CDO68661.1 - 0.019 15.3 1.8 0.019 15.3 1.8 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF5082) DUF2730 PF10805.8 CDO68661.1 - 0.022 14.9 9.6 0.068 13.3 2.5 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) Roughex PF06020.11 CDO68661.1 - 0.022 13.9 3.5 0.034 13.2 3.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4988 PF16378.5 CDO68661.1 - 0.028 14.1 0.2 0.48 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function TRPM_tetra PF16519.5 CDO68661.1 - 0.033 14.3 5.5 0.37 10.9 1.6 2.4 2 0 0 2 2 2 0 Tetramerisation domain of TRPM bZIP_1 PF00170.21 CDO68661.1 - 0.038 14.1 4.4 1.4 9.1 0.7 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF4164 PF13747.6 CDO68661.1 - 0.038 14.3 3.8 0.15 12.3 3.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) BLOC1_2 PF10046.9 CDO68661.1 - 0.049 13.9 5.8 2.7 8.4 0.2 2.6 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CdvA PF18822.1 CDO68661.1 - 0.059 13.2 3.5 0.43 10.4 2.3 2.6 1 1 1 2 2 2 0 CdvA-like coiled-coil domain IFT57 PF10498.9 CDO68661.1 - 0.062 12.3 7.4 0.13 11.2 2.1 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 AAA_13 PF13166.6 CDO68661.1 - 0.065 11.9 4.6 0.02 13.5 0.9 1.8 2 0 0 2 2 2 0 AAA domain CLZ PF16526.5 CDO68661.1 - 0.09 13.1 16.8 0.2 12.0 1.8 3.4 4 0 0 4 4 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 CDO68661.1 - 0.1 12.8 10.4 0.3 11.3 5.5 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 CDO68661.1 - 0.15 10.6 4.3 0.16 10.4 3.8 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family LPP PF04728.13 CDO68661.1 - 0.15 12.5 8.2 1.2 9.6 0.1 3.0 3 1 0 3 3 2 0 Lipoprotein leucine-zipper PuR_N PF09182.10 CDO68661.1 - 0.21 11.6 0.4 0.49 10.4 0.4 1.7 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal NPV_P10 PF05531.12 CDO68661.1 - 0.21 12.1 11.1 0.37 11.3 0.2 3.0 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF4795 PF16043.5 CDO68661.1 - 0.22 11.1 13.9 0.22 11.1 6.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) Tropomyosin PF00261.20 CDO68661.1 - 0.24 10.8 13.2 0.084 12.2 4.3 2.9 2 1 0 2 2 2 0 Tropomyosin Tropomyosin_1 PF12718.7 CDO68661.1 - 0.36 11.0 15.4 0.77 9.9 0.4 3.1 2 1 1 3 3 3 0 Tropomyosin like DUF948 PF06103.11 CDO68661.1 - 0.39 11.0 14.2 0.47 10.7 1.7 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Lectin_N PF03954.14 CDO68661.1 - 0.43 10.3 10.0 1.4 8.7 2.8 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DegS PF05384.11 CDO68661.1 - 0.62 9.5 7.5 0.024 14.1 1.3 1.8 2 0 0 2 2 1 0 Sensor protein DegS V_ATPase_I PF01496.19 CDO68661.1 - 0.68 7.8 10.5 0.082 10.8 2.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 CDO68661.1 - 0.89 9.6 7.5 1.2 9.2 3.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Mer2 PF09074.10 CDO68661.1 - 1.2 9.0 10.1 0.055 13.3 3.7 2.0 2 1 0 2 2 1 0 Mer2 DASH_Dam1 PF08653.10 CDO68661.1 - 1.3 8.9 3.2 18 5.2 0.6 2.7 2 1 0 2 2 2 0 DASH complex subunit Dam1 CCDC53 PF10152.9 CDO68661.1 - 1.4 9.4 16.1 1.1 9.6 12.9 2.3 2 1 0 2 2 1 0 Subunit CCDC53 of WASH complex OmpH PF03938.14 CDO68661.1 - 1.4 9.2 13.3 14 6.1 5.5 2.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Siah-Interact_N PF09032.11 CDO68661.1 - 1.6 9.1 10.6 13 6.1 0.1 2.8 2 0 0 2 2 2 0 Siah interacting protein, N terminal Suf PF05843.14 CDO68661.1 - 1.6 8.6 7.1 0.8 9.6 4.8 1.6 2 0 0 2 2 1 0 Suppressor of forked protein (Suf) DLP_helical PF18709.1 CDO68661.1 - 2 7.5 8.9 0.12 11.5 2.2 2.2 2 1 0 2 2 2 0 Dynamin-like helical domain Ax_dynein_light PF10211.9 CDO68661.1 - 2.1 8.2 14.0 7.1 6.5 1.0 3.1 2 1 1 3 3 3 0 Axonemal dynein light chain Hemagglutinin PF00509.18 CDO68661.1 - 2.2 6.6 4.7 13 4.0 4.2 1.9 1 1 1 2 2 2 0 Haemagglutinin DUF1664 PF07889.12 CDO68661.1 - 2.6 8.1 14.9 0.18 11.8 1.9 2.9 2 2 1 3 3 2 0 Protein of unknown function (DUF1664) Spt20 PF12090.8 CDO68661.1 - 3.4 7.2 11.0 6.5 6.3 11.0 1.4 1 0 0 1 1 1 0 Spt20 family Seryl_tRNA_N PF02403.22 CDO68661.1 - 4.2 7.7 8.7 0.35 11.1 1.2 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2802 PF10975.8 CDO68661.1 - 4.4 7.5 13.1 2.8 8.1 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) YabA PF06156.13 CDO68661.1 - 4.8 7.9 11.2 7.3 7.3 1.1 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Prominin PF05478.11 CDO68661.1 - 4.8 5.0 8.2 0.23 9.4 2.4 1.6 2 0 0 2 2 2 0 Prominin TMPIT PF07851.13 CDO68661.1 - 5.7 6.1 5.9 0.83 8.8 1.2 1.8 2 0 0 2 2 2 0 TMPIT-like protein DASH_Dad2 PF08654.10 CDO68661.1 - 6.6 7.2 17.6 0.35 11.3 0.2 3.5 3 1 0 3 3 2 0 DASH complex subunit Dad2 CPSF100_C PF13299.6 CDO68661.1 - 6.9 6.8 8.7 5.5 7.1 1.2 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4419 PF14388.6 CDO68662.1 - 1.5e-72 244.5 0.5 1.7e-60 205.0 0.3 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) DUF4419 PF14388.6 CDO68663.1 - 1.3e-99 333.5 0.0 2e-99 332.8 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) DUF16 PF01519.16 CDO68664.1 - 3.8e-05 24.1 1.3 6.2e-05 23.4 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF16 Tropomyosin PF00261.20 CDO68664.1 - 0.00021 20.7 3.6 0.00032 20.2 3.6 1.2 1 0 0 1 1 1 1 Tropomyosin DUF4763 PF15960.5 CDO68664.1 - 0.00038 19.8 1.0 0.00059 19.2 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) PspA_IM30 PF04012.12 CDO68664.1 - 0.00043 19.9 2.1 0.00056 19.6 1.5 1.4 1 1 0 1 1 1 1 PspA/IM30 family Fez1 PF06818.15 CDO68664.1 - 0.00051 20.6 0.3 0.0015 19.0 0.5 1.5 2 0 0 2 2 1 1 Fez1 DUF2730 PF10805.8 CDO68664.1 - 0.0006 19.9 5.6 0.0016 18.5 5.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2730) ATG16 PF08614.11 CDO68664.1 - 0.0009 19.5 3.7 0.0013 19.0 3.7 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SlyX PF04102.12 CDO68664.1 - 0.00098 19.7 1.0 0.00098 19.7 1.0 2.2 2 0 0 2 2 2 1 SlyX Tropomyosin_1 PF12718.7 CDO68664.1 - 0.0015 18.7 4.3 0.0037 17.4 4.3 1.6 1 1 0 1 1 1 1 Tropomyosin like CLZ PF16526.5 CDO68664.1 - 0.0021 18.4 6.8 0.15 12.4 1.4 2.4 1 1 1 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PEARLI-4 PF05278.12 CDO68664.1 - 0.0026 17.4 1.9 0.0037 16.9 1.9 1.2 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) DUF2046 PF09755.9 CDO68664.1 - 0.0036 16.6 0.3 0.0089 15.3 0.6 1.5 2 0 0 2 2 1 1 Uncharacterized conserved protein H4 (DUF2046) BLOC1_2 PF10046.9 CDO68664.1 - 0.0079 16.5 4.2 0.021 15.1 4.2 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 CDO68664.1 - 0.014 15.4 3.5 0.024 14.6 3.5 1.3 1 0 0 1 1 1 0 Laminin Domain II NPV_P10 PF05531.12 CDO68664.1 - 0.017 15.6 6.6 0.18 12.3 6.6 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 CDO68664.1 - 0.018 15.0 5.1 0.073 13.1 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 CDO68664.1 - 0.022 14.8 2.5 0.12 12.5 1.4 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 CDO68664.1 - 0.031 13.6 1.6 0.042 13.2 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 CDO68664.1 - 0.032 14.5 3.4 0.13 12.5 3.4 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CDO68664.1 - 0.033 14.2 2.5 0.072 13.1 1.9 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.12 CDO68664.1 - 0.035 14.1 0.1 0.076 13.0 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 CDO68664.1 - 0.035 14.3 7.0 7.4 6.9 1.1 2.4 1 1 0 1 1 1 0 Haemolysin XhlA DUF4686 PF15742.5 CDO68664.1 - 0.039 13.1 4.5 0.054 12.6 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) HrpB7 PF09486.10 CDO68664.1 - 0.05 14.0 1.5 0.05 14.0 1.5 1.6 2 0 0 2 2 1 0 Bacterial type III secretion protein (HrpB7) FlaC_arch PF05377.11 CDO68664.1 - 0.052 13.9 3.9 0.052 13.9 3.9 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) LPP PF04728.13 CDO68664.1 - 0.066 13.6 2.3 1.6 9.2 0.6 2.9 1 1 3 4 4 4 0 Lipoprotein leucine-zipper FH2 PF02181.23 CDO68664.1 - 0.068 12.3 0.7 0.1 11.7 0.6 1.3 1 1 0 1 1 1 0 Formin Homology 2 Domain Spc7 PF08317.11 CDO68664.1 - 0.082 11.8 2.3 0.12 11.3 2.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 CDO68664.1 - 0.095 12.9 0.5 0.16 12.2 0.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.15 CDO68664.1 - 0.11 12.6 6.2 0.36 11.0 1.1 2.8 1 1 2 3 3 3 0 Basic region leucine zipper BRI3BP PF14965.6 CDO68664.1 - 0.11 12.0 3.9 1.9 7.9 0.3 2.3 1 1 1 2 2 2 0 Negative regulator of p53/TP53 MbeD_MobD PF04899.12 CDO68664.1 - 0.12 12.5 0.6 0.31 11.2 0.2 1.9 1 1 1 2 2 1 0 MbeD/MobD like bZIP_1 PF00170.21 CDO68664.1 - 0.13 12.4 2.4 0.43 10.7 1.0 2.1 1 1 1 2 2 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 CDO68664.1 - 0.13 12.2 6.0 0.24 11.4 6.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 CDO68664.1 - 0.14 10.8 0.4 0.18 10.4 0.4 1.1 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.14 CDO68664.1 - 0.17 11.7 1.3 0.27 11.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BST2 PF16716.5 CDO68664.1 - 0.23 12.1 1.9 0.37 11.4 1.9 1.3 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 TSC22 PF01166.18 CDO68664.1 - 0.36 11.2 4.0 0.47 10.8 1.1 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family Rota_NSP3 PF01665.16 CDO68664.1 - 0.39 9.8 2.0 0.89 8.6 2.0 1.5 1 1 0 1 1 1 0 Rotavirus non-structural protein NSP3 DUF5082 PF16888.5 CDO68664.1 - 0.4 11.0 2.4 3.7 7.8 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4795 PF16043.5 CDO68664.1 - 0.41 10.2 3.9 0.89 9.1 3.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ZapB PF06005.12 CDO68664.1 - 0.46 11.0 5.2 1 9.9 4.8 1.7 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CDO68664.1 - 0.46 10.3 3.6 1.7 8.4 1.6 2.2 1 1 1 2 2 2 0 Septum formation initiator CCDC53 PF10152.9 CDO68664.1 - 0.59 10.5 4.9 2 8.8 3.2 2.6 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Fes1 PF08609.10 CDO68664.1 - 0.62 11.0 4.0 8.1 7.4 4.0 2.3 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 KLRAQ PF10205.9 CDO68664.1 - 0.73 10.1 5.1 1.2 9.4 5.1 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF4988 PF16378.5 CDO68664.1 - 0.82 9.3 3.0 7.8 6.1 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function CCDC-167 PF15188.6 CDO68664.1 - 0.89 9.9 4.8 16 5.9 0.6 3.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3552 PF12072.8 CDO68664.1 - 1 8.8 7.3 0.31 10.4 4.7 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF3552) Lge1 PF11488.8 CDO68664.1 - 1.6 9.0 4.2 57 4.0 4.2 2.3 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Uds1 PF15456.6 CDO68664.1 - 5.7 7.1 8.1 14 5.9 4.1 2.5 2 1 0 2 2 1 0 Up-regulated During Septation Clusterin PF01093.17 CDO68665.1 - 6.1e-05 22.3 0.0 7.7e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Clusterin Tropomyosin PF00261.20 CDO68665.1 - 0.00036 20.0 2.8 0.00069 19.1 2.8 1.4 1 0 0 1 1 1 1 Tropomyosin DUF4795 PF16043.5 CDO68665.1 - 0.00088 18.9 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DegS PF05384.11 CDO68665.1 - 0.0015 18.1 1.0 0.0027 17.2 1.0 1.4 1 0 0 1 1 1 1 Sensor protein DegS XhlA PF10779.9 CDO68665.1 - 0.0019 18.4 1.5 0.0036 17.5 1.5 1.5 1 0 0 1 1 1 1 Haemolysin XhlA TMF_TATA_bd PF12325.8 CDO68665.1 - 0.0019 18.4 1.0 0.0036 17.5 1.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Filament PF00038.21 CDO68665.1 - 0.0019 17.8 0.9 0.003 17.2 0.9 1.2 1 0 0 1 1 1 1 Intermediate filament protein BLOC1_2 PF10046.9 CDO68665.1 - 0.0021 18.3 1.3 0.0043 17.3 1.3 1.5 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 CDO68665.1 - 0.0022 18.1 1.6 0.0045 17.0 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF2730 PF10805.8 CDO68665.1 - 0.0024 17.9 1.5 0.0053 16.8 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Prefoldin_2 PF01920.20 CDO68665.1 - 0.0028 17.6 1.3 0.0052 16.7 1.3 1.5 1 0 0 1 1 1 1 Prefoldin subunit ATG16 PF08614.11 CDO68665.1 - 0.0029 17.9 0.4 0.0051 17.1 0.4 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 CDO68665.1 - 0.0033 17.5 1.3 0.006 16.6 1.3 1.3 1 0 0 1 1 1 1 Laminin Domain II DUF16 PF01519.16 CDO68665.1 - 0.0039 17.7 0.4 0.0068 16.9 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF16 Spc29 PF17082.5 CDO68665.1 - 0.0048 16.8 0.2 0.0066 16.3 0.2 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 FlaC_arch PF05377.11 CDO68665.1 - 0.005 17.2 2.9 0.29 11.5 0.4 2.5 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) PEARLI-4 PF05278.12 CDO68665.1 - 0.0052 16.4 2.4 0.008 15.8 2.4 1.2 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) NPV_P10 PF05531.12 CDO68665.1 - 0.0064 16.9 1.0 0.029 14.8 1.0 2.1 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 CDO68665.1 - 0.0066 15.8 0.4 0.0089 15.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) ADIP PF11559.8 CDO68665.1 - 0.0097 16.0 1.1 0.017 15.2 1.1 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.12 CDO68665.1 - 0.0099 15.9 0.8 0.017 15.1 0.1 1.8 2 0 0 2 2 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ZapB PF06005.12 CDO68665.1 - 0.0099 16.3 1.5 0.029 14.8 1.5 1.8 1 0 0 1 1 1 1 Cell division protein ZapB bZIP_2 PF07716.15 CDO68665.1 - 0.011 15.8 1.7 0.02 15.0 1.4 1.7 1 1 0 1 1 1 0 Basic region leucine zipper CLZ PF16526.5 CDO68665.1 - 0.012 16.0 3.0 0.09 13.1 3.0 2.3 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FliD_C PF07195.12 CDO68665.1 - 0.013 15.0 0.5 0.022 14.2 0.5 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus HsbA PF12296.8 CDO68665.1 - 0.016 15.6 0.0 0.51 10.8 0.0 2.2 1 1 1 2 2 2 0 Hydrophobic surface binding protein A GAS PF13851.6 CDO68665.1 - 0.018 14.4 1.9 0.029 13.7 1.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 CDO68665.1 - 0.019 13.9 1.0 0.019 13.9 1.0 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein FPP PF05911.11 CDO68665.1 - 0.02 13.1 0.1 0.028 12.6 0.1 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil ABC_tran_CTD PF16326.5 CDO68665.1 - 0.021 15.1 1.1 0.14 12.4 1.2 2.2 1 1 0 1 1 1 0 ABC transporter C-terminal domain RmuC PF02646.16 CDO68665.1 - 0.023 13.8 0.3 0.035 13.2 0.3 1.2 1 0 0 1 1 1 0 RmuC family Laminin_I PF06008.14 CDO68665.1 - 0.024 14.3 1.0 0.04 13.6 1.0 1.3 1 0 0 1 1 1 0 Laminin Domain I TMF_DNA_bd PF12329.8 CDO68665.1 - 0.026 14.5 1.1 0.054 13.5 1.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PspA_IM30 PF04012.12 CDO68665.1 - 0.026 14.1 0.4 0.048 13.2 0.4 1.4 1 0 0 1 1 1 0 PspA/IM30 family Tropomyosin_1 PF12718.7 CDO68665.1 - 0.032 14.4 1.9 0.032 14.4 1.9 1.5 2 0 0 2 2 1 0 Tropomyosin like BRE1 PF08647.11 CDO68665.1 - 0.033 14.2 2.4 0.066 13.3 2.4 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF1640 PF07798.11 CDO68665.1 - 0.034 14.2 2.7 0.066 13.3 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Cluap1 PF10234.9 CDO68665.1 - 0.038 13.4 1.3 0.061 12.7 1.3 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 GPS2_interact PF15784.5 CDO68665.1 - 0.039 14.4 2.1 0.22 12.0 2.1 2.2 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Snapin_Pallidin PF14712.6 CDO68665.1 - 0.05 14.0 1.9 0.13 12.7 1.9 1.7 1 0 0 1 1 1 0 Snapin/Pallidin MscS_porin PF12795.7 CDO68665.1 - 0.055 13.0 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Ax_dynein_light PF10211.9 CDO68665.1 - 0.06 13.3 0.6 0.06 13.3 0.6 1.6 2 0 0 2 2 1 0 Axonemal dynein light chain Fib_alpha PF08702.10 CDO68665.1 - 0.061 13.5 0.4 0.13 12.5 0.4 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 CDO68665.1 - 0.063 12.6 0.2 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 CDO68665.1 - 0.067 13.3 1.9 0.14 12.3 1.8 1.6 1 1 0 1 1 1 0 bZIP transcription factor Macoilin PF09726.9 CDO68665.1 - 0.068 11.7 0.3 0.082 11.5 0.3 1.1 1 0 0 1 1 1 0 Macoilin family AAA_13 PF13166.6 CDO68665.1 - 0.077 11.6 0.1 0.1 11.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain Spectrin PF00435.21 CDO68665.1 - 0.088 13.3 0.6 0.17 12.4 0.6 1.4 1 0 0 1 1 1 0 Spectrin repeat DUF3086 PF11285.8 CDO68665.1 - 0.095 11.8 0.2 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) STAT_alpha PF01017.20 CDO68665.1 - 0.096 12.6 0.5 0.15 12.0 0.5 1.5 1 1 0 1 1 1 0 STAT protein, all-alpha domain CEP209_CC5 PF16574.5 CDO68665.1 - 0.12 12.5 4.0 2.4 8.3 2.5 2.1 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 BRI3BP PF14965.6 CDO68665.1 - 0.13 11.8 0.5 0.2 11.2 0.5 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 TRAF_BIRC3_bd PF16673.5 CDO68665.1 - 0.14 12.0 2.7 1.3 8.9 2.7 2.2 1 1 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Nsp1_C PF05064.13 CDO68665.1 - 0.14 12.0 2.4 0.17 11.7 0.9 1.9 2 0 0 2 2 2 0 Nsp1-like C-terminal region EMP24_GP25L PF01105.24 CDO68665.1 - 0.14 12.1 1.2 0.25 11.2 1.2 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Bacillus_HBL PF05791.11 CDO68665.1 - 0.15 11.9 0.3 0.26 11.1 0.3 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TolA_bind_tri PF16331.5 CDO68665.1 - 0.17 12.0 1.2 0.55 10.4 0.6 1.9 1 1 0 1 1 1 0 TolA binding protein trimerisation FAM76 PF16046.5 CDO68665.1 - 0.22 10.9 0.2 0.28 10.5 0.2 1.1 1 0 0 1 1 1 0 FAM76 protein Prominin PF05478.11 CDO68665.1 - 0.25 9.3 0.4 0.33 8.9 0.4 1.1 1 0 0 1 1 1 0 Prominin HSBP1 PF06825.12 CDO68665.1 - 0.27 11.1 3.2 0.86 9.5 3.0 2.0 1 1 0 1 1 1 0 Heat shock factor binding protein 1 CENP-F_leu_zip PF10473.9 CDO68665.1 - 0.41 10.7 5.6 0.14 12.2 2.5 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 CDO68665.1 - 0.6 10.8 5.7 0.61 10.7 0.4 2.6 2 1 1 3 3 2 0 SlyX LPP PF04728.13 CDO68665.1 - 0.61 10.5 2.3 5.4 7.5 0.4 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF948 PF06103.11 CDO68665.1 - 1.4 9.2 3.7 1.6 9.0 0.9 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Csm1_N PF18504.1 CDO68665.1 - 4 7.9 8.3 0.45 10.9 1.7 2.5 2 1 1 3 3 2 0 Csm1 N-terminal domain Spc24 PF08286.11 CDO68665.1 - 4.7 7.5 5.7 4.1 7.7 2.9 2.2 2 1 0 2 2 1 0 Spc24 subunit of Ndc80 G-patch_2 PF12656.7 CDO68666.1 - 2e-24 85.4 0.2 7.3e-24 83.6 0.2 2.1 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 CDO68666.1 - 0.0034 17.3 0.7 0.0084 16.0 0.7 1.8 1 0 0 1 1 1 1 G-patch domain Sec2p PF06428.11 CDO68667.1 - 6e-15 55.0 9.4 6e-15 55.0 9.4 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF5597 PF18120.1 CDO68667.1 - 0.027 14.6 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5597) Spc7 PF08317.11 CDO68667.1 - 0.032 13.1 18.9 0.011 14.6 10.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 CDO68667.1 - 0.14 11.9 6.6 1.7 8.5 0.8 3.2 2 1 0 2 2 2 0 Septum formation initiator KxDL PF10241.9 CDO68667.1 - 0.55 10.5 4.2 14 6.1 0.1 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein Herpes_UL6 PF01763.16 CDO68667.1 - 0.74 8.3 7.1 2.2 6.7 7.1 1.7 1 1 0 1 1 1 0 Herpesvirus UL6 like DUF4200 PF13863.6 CDO68667.1 - 0.86 10.0 9.9 0.37 11.2 5.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CTU2 PF10288.9 CDO68667.1 - 0.96 9.7 0.0 0.96 9.7 0.0 3.2 4 1 0 4 4 4 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF1664 PF07889.12 CDO68667.1 - 1 9.4 10.5 3.2 7.8 1.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Noelin-1 PF12308.8 CDO68667.1 - 1.1 9.3 6.5 0.51 10.3 2.1 2.3 2 0 0 2 2 2 0 Neurogenesis glycoprotein HALZ PF02183.18 CDO68667.1 - 1.7 8.9 4.1 10 6.5 0.1 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper Rab5-bind PF09311.11 CDO68667.1 - 3.7 6.9 18.8 1.7 7.9 8.0 2.1 1 1 1 2 2 2 0 Rabaptin-like protein AAA_13 PF13166.6 CDO68667.1 - 7.5 5.1 11.7 16 4.0 11.7 1.5 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 CDO68667.1 - 8.9 5.3 12.3 3.7 6.5 5.1 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SIS PF01380.22 CDO68668.1 - 8.7e-65 216.5 0.2 4.5e-33 113.9 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CDO68668.1 - 9.3e-16 58.2 0.0 2.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CDO68668.1 - 1.8e-11 44.0 0.0 4.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CDO68668.1 - 0.00015 20.8 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 CDO68668.1 - 0.026 14.5 0.0 0.77 9.8 0.0 2.6 2 1 1 3 3 3 0 SIS domain TENA_THI-4 PF03070.16 CDO68669.1 - 0.095 12.5 0.0 0.26 11.1 0.0 1.7 1 1 0 1 1 1 0 TENA/THI-4/PQQC family Sec23_trunk PF04811.15 CDO68670.1 - 2.7e-76 256.4 0.0 5.3e-76 255.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CDO68670.1 - 6.6e-24 83.7 0.2 1.8e-23 82.3 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CDO68670.1 - 1.5e-17 64.1 0.0 3.9e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CDO68670.1 - 6.9e-16 58.0 6.5 1.3e-15 57.1 6.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CDO68670.1 - 1.3e-09 37.8 0.0 2.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CDO68670.1 - 0.0025 17.2 0.4 0.0052 16.2 0.4 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain WW PF00397.26 CDO68670.1 - 0.069 13.2 6.3 3.4 7.8 0.3 2.7 2 0 0 2 2 2 0 WW domain MFS_1 PF07690.16 CDO68671.1 - 2.5e-20 72.7 44.3 2.4e-15 56.3 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RHS_repeat PF05593.14 CDO68672.1 - 0.078 13.5 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 RHS Repeat RVT_1 PF00078.27 CDO68673.1 - 9.9e-36 123.3 0.0 1.4e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO68673.1 - 1.8e-09 37.9 0.0 3.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO68673.1 - 0.0027 18.4 0.5 0.0071 17.0 0.5 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_2 PF07727.14 CDO68674.1 - 1.3e-05 25.0 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Proteasome PF00227.26 CDO68676.1 - 1.4e-40 138.8 0.3 1.3e-19 70.4 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit CSN8_PSD8_EIF3K PF10075.9 CDO68677.1 - 1.7e-29 102.6 0.1 2.8e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CDO68677.1 - 6.8e-05 22.4 0.0 9.3e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family AvrPphF-ORF-2 PF09143.10 CDO68677.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 AvrPphF-ORF-2 Proteasome PF00227.26 CDO68678.1 - 1.8e-35 122.2 0.1 2.5e-20 72.8 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 CDO68678.1 - 1.9e-13 49.8 0.1 3e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PfaD_N PF18328.1 CDO68678.1 - 0.11 12.5 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Fatty acid synthase subunit PfaD N-terminal domain Nup88 PF10168.9 CDO68679.1 - 1.2e-18 66.3 1.5 2.1e-11 42.4 0.0 3.2 3 0 0 3 3 3 2 Nuclear pore component ANAPC4_WD40 PF12894.7 CDO68679.1 - 0.16 12.3 0.0 15 6.0 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup54 PF13874.6 CDO68679.1 - 0.88 9.7 13.3 0.091 12.9 6.6 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 4HBT PF03061.22 CDO68680.1 - 6e-06 26.5 0.1 1.3e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily Adenine_deam_C PF13382.6 CDO68680.1 - 0.017 14.4 0.1 0.033 13.5 0.0 1.5 2 0 0 2 2 2 0 Adenine deaminase C-terminal domain RSN1_7TM PF02714.15 CDO68681.1 - 2.1e-77 260.1 25.3 3.1e-77 259.6 25.3 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CDO68681.1 - 1.8e-37 129.2 0.0 2.7e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CDO68681.1 - 3e-21 75.8 0.0 1.8e-20 73.3 0.0 2.4 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport Halogen_Hydrol PF10112.9 CDO68681.1 - 0.068 13.2 0.0 0.068 13.2 0.0 2.5 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Nsp1_C PF05064.13 CDO68682.1 - 7.3e-34 116.1 0.2 2.6e-33 114.3 0.3 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 CDO68682.1 - 2.1e-19 70.2 115.8 1.4e-08 35.5 28.0 7.3 1 1 4 5 5 5 4 Nucleoporin FG repeat region CENP-Q PF13094.6 CDO68682.1 - 0.0011 19.1 4.5 0.12 12.5 2.2 2.3 1 1 1 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin-6_N PF09177.11 CDO68682.1 - 0.94 10.1 3.0 21 5.8 3.0 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 CDO68682.1 - 3.6 8.1 4.3 91 3.6 0.0 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.16 CDO68683.1 - 2e-42 145.4 41.0 2e-42 145.4 41.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO68683.1 - 4.5e-08 32.4 9.8 4.5e-08 32.4 9.8 3.3 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 CDO68683.1 - 0.0055 15.2 2.6 0.01 14.3 2.6 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector FPN1 PF06963.12 CDO68683.1 - 0.012 14.2 0.0 0.025 13.2 0.0 1.5 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Sensor_TM1 PF13755.6 CDO68683.1 - 0.036 13.8 0.8 0.1 12.4 0.8 1.7 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain DUF21 PF01595.20 CDO68683.1 - 0.28 10.9 3.4 0.96 9.1 0.7 2.9 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain DEAD PF00270.29 CDO68684.1 - 3.7e-52 176.6 0.0 6.6e-51 172.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO68684.1 - 9.1e-27 93.6 0.0 3.3e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO68684.1 - 0.0025 17.9 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NuDC PF16273.5 CDO68684.1 - 0.008 16.7 0.1 0.008 16.7 0.1 5.3 6 0 0 6 6 6 1 Nuclear distribution C domain GHMP_kinases_C PF08544.13 CDO68684.1 - 0.03 14.7 0.3 4.3 7.8 0.0 4.2 4 0 0 4 4 4 0 GHMP kinases C terminal AviRa PF11599.8 CDO68684.1 - 0.19 11.2 0.9 0.56 9.6 0.9 1.7 1 0 0 1 1 1 0 RRNA methyltransferase AviRa PI31_Prot_N PF11566.8 CDO68685.1 - 1.1e-44 152.1 0.0 1.1e-44 152.1 0.0 1.6 2 0 0 2 2 2 1 PI31 proteasome regulator N-terminal Ank_4 PF13637.6 CDO68686.1 - 6.7e-31 106.3 7.5 1.7e-13 50.8 0.2 4.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDO68686.1 - 1.3e-28 98.6 0.8 7.8e-10 38.8 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDO68686.1 - 2.7e-27 95.2 0.1 1.6e-15 57.4 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDO68686.1 - 3.1e-21 73.2 0.7 2.9e-05 24.1 0.0 5.5 4 1 1 5 5 5 3 Ankyrin repeat Ank PF00023.30 CDO68686.1 - 5.7e-17 61.3 1.8 0.0017 18.7 0.1 5.0 4 1 1 5 5 5 3 Ankyrin repeat FYVE PF01363.21 CDO68686.1 - 2.7e-16 59.4 9.9 2.7e-16 59.4 9.9 2.3 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_11 PF17123.5 CDO68686.1 - 0.0086 15.8 2.0 0.0086 15.8 2.0 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_9 PF13901.6 CDO68686.1 - 0.016 15.2 0.6 0.035 14.1 0.6 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_2 PF13639.6 CDO68686.1 - 0.029 14.7 14.9 0.056 13.8 1.5 3.6 3 0 0 3 3 3 0 Ring finger domain FYVE_2 PF02318.16 CDO68686.1 - 3.4 7.9 10.1 0.35 11.1 3.2 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger NAD_binding_6 PF08030.12 CDO68687.1 - 3.1e-16 59.9 0.0 4.7e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 CDO68687.1 - 1.1e-14 54.6 13.8 1.2e-14 54.5 10.9 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CDO68687.1 - 7.2e-14 51.8 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CDO68687.1 - 0.021 15.5 0.0 0.044 14.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Aminotran_1_2 PF00155.21 CDO68688.1 - 1.3e-66 225.2 0.0 1.5e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CDO68688.1 - 2.2e-06 27.2 0.0 4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CDO68688.1 - 1.9e-05 23.4 0.0 5e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CDO68688.1 - 0.00019 20.9 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CDO68688.1 - 0.00047 19.2 0.0 0.011 14.7 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Sec63 PF02889.16 CDO68689.1 - 6.5e-75 251.6 0.0 9.5e-75 251.1 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 CDO68689.1 - 8.1e-34 116.9 0.4 6e-26 91.3 0.2 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 CDO68689.1 - 9.2e-14 51.8 0.0 1.1e-10 41.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDO68689.1 - 2.6e-06 27.8 0.1 0.00016 22.0 0.0 3.6 3 2 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDO68689.1 - 4.6e-05 23.7 0.3 0.0021 18.3 0.2 3.0 2 1 0 2 2 2 1 AAA domain SNF2_N PF00176.23 CDO68689.1 - 0.021 13.5 0.2 0.036 12.8 0.2 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Glyco_transf_4 PF13439.6 CDO68689.1 - 0.065 13.2 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 AAA_11 PF13086.6 CDO68689.1 - 0.088 12.6 0.2 0.58 9.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 CDO68689.1 - 0.12 12.7 0.9 0.33 11.3 0.2 2.1 2 0 0 2 2 2 0 AAA domain Xan_ur_permease PF00860.20 CDO68690.1 - 1.4e-31 109.6 26.4 4.4e-21 75.0 7.7 3.3 3 1 1 4 4 4 3 Permease family SLATT_5 PF18160.1 CDO68690.1 - 0.13 11.5 0.1 0.13 11.5 0.1 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4870 PF09685.10 CDO68691.1 - 0.13 12.4 1.9 0.22 11.7 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) DUF2512 PF10710.9 CDO68691.1 - 0.21 11.3 2.9 0.36 10.5 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) EMC3_TMCO1 PF01956.16 CDO68692.1 - 5.9e-37 127.0 0.0 7.3e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like EF-hand_7 PF13499.6 CDO68693.1 - 5.8e-27 94.0 3.9 4.1e-18 65.6 1.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CDO68693.1 - 4.7e-24 82.1 11.0 2.5e-08 32.9 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CDO68693.1 - 2.2e-20 70.8 6.8 1.5e-06 27.7 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CDO68693.1 - 1.7e-13 50.2 10.2 5.2e-06 26.2 0.8 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CDO68693.1 - 4.7e-13 48.0 9.4 0.00037 19.8 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 CDO68693.1 - 1.2e-05 25.2 4.9 0.083 12.8 0.1 3.6 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDO68693.1 - 0.00027 21.2 1.9 0.24 11.7 0.3 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CDO68693.1 - 0.0033 17.7 1.6 0.1 12.9 0.1 2.8 2 1 1 3 3 3 1 EF-hand domain EF-hand_3 PF09069.11 CDO68693.1 - 0.013 15.9 0.0 0.053 14.0 0.0 1.9 2 0 0 2 2 2 0 EF-hand Pan3_PK PF18101.1 CDO68693.1 - 0.051 13.6 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 Pan3 Pseudokinase domain Caleosin PF05042.13 CDO68693.1 - 0.075 13.0 2.0 8.5 6.3 0.0 3.1 2 1 1 3 3 3 0 Caleosin related protein DUF1298 PF06974.13 CDO68693.1 - 0.22 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) WD40 PF00400.32 CDO68695.1 - 0.00013 22.7 0.1 0.067 14.1 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO68695.1 - 0.00027 21.2 0.0 1 9.7 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 CDO68695.1 - 0.01 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) DUF839 PF05787.13 CDO68695.1 - 0.049 12.8 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) Plavaka PF18759.1 CDO68696.1 - 9.7e-29 100.6 0.2 2e-28 99.6 0.2 1.5 1 0 0 1 1 1 1 Plavaka transposase ATE_C PF04377.15 CDO68698.1 - 2.8e-41 141.3 1.0 2.5e-25 89.6 0.1 2.4 2 0 0 2 2 2 2 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CDO68698.1 - 4.2e-19 68.7 1.6 7.5e-19 67.9 1.6 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Peptidase_S24 PF00717.23 CDO68698.1 - 1.8e-07 31.0 0.0 5.2e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like KCH PF16944.5 CDO68699.1 - 2.5e-84 283.0 13.5 3.4e-84 282.6 13.5 1.1 1 0 0 1 1 1 1 Fungal potassium channel TFIIA PF03153.13 CDO68699.1 - 0.086 12.8 10.3 0.11 12.5 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Abhydrolase_1 PF00561.20 CDO68700.1 - 2.7e-18 66.6 0.0 7.5e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO68700.1 - 2.4e-14 53.2 0.0 6.7e-13 48.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO68700.1 - 7.4e-12 46.3 0.1 1.1e-11 45.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CDO68700.1 - 0.00032 20.4 0.0 0.00079 19.1 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 CDO68700.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 CDO68701.1 - 6e-21 75.2 0.0 8.2e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO68701.1 - 2.1e-13 50.1 0.0 7.7e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO68701.1 - 5.1e-12 46.9 0.2 7.6e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CDO68701.1 - 0.012 15.2 0.0 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1057 PF06342.12 CDO68701.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) MMR_HSR1_Xtn PF16897.5 CDO68702.1 - 3.2e-42 142.8 0.8 2.8e-41 139.8 0.4 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CDO68702.1 - 1.1e-25 89.4 0.1 2e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CDO68702.1 - 3.5e-20 72.2 0.0 7.7e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDO68702.1 - 3.8e-08 33.0 0.1 1.1e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CDO68702.1 - 0.0026 16.8 0.5 0.021 13.8 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CDO68702.1 - 0.045 13.8 0.4 12 5.9 0.3 2.3 1 1 1 2 2 2 0 Dynamin family GTP_EFTU PF00009.27 CDO68702.1 - 0.11 12.0 0.4 16 4.9 0.1 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Glyco_hydro_66 PF13199.6 CDO68702.1 - 0.17 10.5 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 RsgA_GTPase PF03193.16 CDO68702.1 - 0.34 10.8 2.1 2.8 7.8 0.1 2.9 3 1 0 3 3 3 0 RsgA GTPase Ribonuc_red_sm PF00268.21 CDO68703.1 - 1e-106 356.5 0.1 1.9e-106 355.6 0.1 1.4 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 CDO68703.1 - 0.17 12.7 0.0 0.31 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Ribonuc_red_sm PF00268.21 CDO68704.1 - 2.6e-124 414.2 2.2 3.2e-124 413.9 2.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 CDO68704.1 - 0.15 12.9 0.0 0.34 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Acetyltransf_4 PF13420.7 CDO68705.1 - 2.9e-22 79.5 0.1 3.7e-22 79.1 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CDO68705.1 - 5.7e-15 56.2 0.2 6.7e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO68705.1 - 3e-13 50.0 0.0 3.7e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO68705.1 - 7.5e-11 42.3 0.0 1.1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDO68705.1 - 3.8e-08 33.3 0.1 7.6e-08 32.4 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDO68705.1 - 9.7e-06 25.5 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 CDO68705.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 CDO68705.1 - 0.0056 16.8 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain UTP15_C PF09384.10 CDO68705.1 - 0.086 12.5 0.1 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 UTP15 C terminal Alg6_Alg8 PF03155.15 CDO68706.1 - 2.1e-119 399.7 34.8 3.1e-43 148.5 4.0 3.0 1 1 2 3 3 3 3 ALG6, ALG8 glycosyltransferase family COX14 PF14880.6 CDO68706.1 - 1.6 8.6 6.5 1.7 8.5 0.7 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Brix PF04427.18 CDO68707.1 - 4.3e-32 111.8 0.5 6e-32 111.3 0.5 1.2 1 0 0 1 1 1 1 Brix domain Acetyltransf_7 PF13508.7 CDO68708.1 - 2.9e-18 66.1 0.1 2.6e-08 34.2 0.0 2.5 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO68708.1 - 4.4e-15 56.0 0.1 1.6e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDO68708.1 - 5.1e-14 52.3 0.1 1.4e-05 25.0 0.0 2.7 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDO68708.1 - 1.8e-11 44.2 0.1 7.9e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDO68708.1 - 1.2e-10 41.2 0.2 1.2e-06 28.4 0.0 2.7 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.6 CDO68708.1 - 9.2e-07 28.9 0.1 0.0016 18.5 0.0 2.5 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase Ntox46 PF15538.6 CDO68708.1 - 0.15 12.0 0.2 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial toxin 46 Acetyltransf_3 PF13302.7 CDO68708.1 - 0.17 12.6 3.7 0.21 12.2 0.5 2.6 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 CDO68708.1 - 0.22 11.2 0.0 4.5 6.9 0.0 2.2 2 0 0 2 2 2 0 MOZ/SAS family Peptidase_M18 PF02127.15 CDO68709.1 - 5.1e-152 506.6 0.0 5.3e-147 490.1 0.0 2.0 2 0 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CDO68709.1 - 0.00031 19.9 0.0 0.03 13.4 0.1 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Acyl-CoA_dh_M PF02770.19 CDO68709.1 - 0.13 12.5 0.0 5.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain WD40 PF00400.32 CDO68710.1 - 1.3e-52 174.6 20.7 1.1e-07 32.4 0.3 11.8 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO68710.1 - 2.2e-24 85.6 2.3 8.1e-05 22.8 0.0 9.7 4 3 4 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CDO68710.1 - 1.6e-15 57.3 0.3 3.3e-15 56.3 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 CDO68710.1 - 7.8e-09 34.7 2.3 0.026 13.2 0.0 4.5 5 0 0 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CDO68710.1 - 4.4e-07 29.2 1.6 0.17 10.8 0.0 5.6 4 2 3 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CDO68710.1 - 0.0028 17.0 0.0 1.8 7.8 0.0 3.5 4 0 0 4 4 4 1 WD40-like domain PPL5 PF18168.1 CDO68710.1 - 0.015 14.6 1.7 0.038 13.3 0.4 2.0 2 0 0 2 2 2 0 Prim-pol family 5 RAB3GAP2_N PF14655.6 CDO68710.1 - 0.016 14.5 0.2 1.3 8.2 0.0 3.2 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PALB2_WD40 PF16756.5 CDO68710.1 - 0.037 12.9 3.1 1.2 8.0 0.0 4.0 4 1 1 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 CDO68710.1 - 0.093 11.5 0.0 31 3.1 0.0 4.0 3 1 2 5 5 5 0 Nup133 N terminal like Coatomer_WDAD PF04053.14 CDO68710.1 - 0.11 11.6 0.0 9.4 5.1 0.0 2.8 3 0 0 3 3 3 0 Coatomer WD associated region DPBB_1 PF03330.18 CDO68711.1 - 1.6e-05 25.1 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase YL1 PF05764.13 CDO68711.1 - 0.0004 20.6 0.1 0.00046 20.4 0.1 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Cys_Met_Meta_PP PF01053.20 CDO68712.1 - 6e-58 196.2 0.0 2.5e-57 194.2 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Acyltransferase PF01553.21 CDO68713.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.5 1 1 0 1 1 1 0 Acyltransferase SNARE_assoc PF09335.11 CDO68714.1 - 2e-15 57.4 8.4 2e-15 57.4 8.4 2.0 1 1 1 2 2 2 1 SNARE associated Golgi protein Syntaxin-18_N PF10496.9 CDO68715.1 - 3.1e-13 49.8 2.0 3.1e-13 49.8 2.0 2.7 2 2 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 CDO68715.1 - 1.4e-06 28.2 0.6 5.4e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 SNARE domain ComR_TPR PF18710.1 CDO68715.1 - 0.042 13.4 1.2 0.098 12.2 0.6 1.8 2 0 0 2 2 2 0 ComR tetratricopeptide DUF3450 PF11932.8 CDO68715.1 - 2.8 7.2 15.5 0.1 11.9 4.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) LSM PF01423.22 CDO68716.1 - 2.4e-19 68.8 0.0 2.6e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDO68716.1 - 0.03 13.9 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Hfq protein MDM10 PF12519.8 CDO68718.1 - 1.7e-96 323.9 0.1 4.2e-85 286.4 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 CDO68718.1 - 0.0011 18.4 0.1 1.1 8.6 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic porin DEAD PF00270.29 CDO68719.1 - 1.1e-16 61.2 0.0 2e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDO68719.1 - 1.5e-12 47.9 0.0 1.2e-11 44.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDO68719.1 - 1.6e-05 25.2 0.0 3.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pex2_Pex12 PF04757.14 CDO68720.1 - 4e-48 163.9 3.8 4.8e-48 163.7 3.8 1.0 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 CDO68720.1 - 5.2e-07 29.4 1.0 7.9e-07 28.8 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDO68720.1 - 1.5e-06 28.0 0.6 2.2e-06 27.4 0.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO68720.1 - 0.00032 21.0 0.8 0.00051 20.3 0.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDO68720.1 - 0.013 15.4 0.7 0.019 14.8 0.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDO68720.1 - 0.044 13.9 1.8 0.075 13.2 1.8 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CDO68720.1 - 0.13 12.3 2.1 0.22 11.6 2.1 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Ank_2 PF12796.7 CDO68721.1 - 1e-38 131.8 0.1 2.3e-11 44.1 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDO68721.1 - 1.2e-32 111.8 1.5 4.4e-09 36.7 0.0 5.0 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDO68721.1 - 2.3e-25 85.8 7.0 0.00061 20.1 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat SPX PF03105.19 CDO68721.1 - 4.1e-24 86.2 7.2 6.3e-08 32.9 0.0 3.3 1 1 2 3 3 3 3 SPX domain Ank_5 PF13857.6 CDO68721.1 - 4.3e-23 81.1 8.7 1.7e-05 25.0 0.0 6.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 CDO68721.1 - 4.5e-21 74.3 6.2 0.1 13.1 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat GDPD PF03009.17 CDO68721.1 - 3.3e-13 50.0 0.0 5.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ABC_tran PF00005.27 CDO68722.1 - 3.3e-22 79.5 0.0 6.7e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDO68722.1 - 1.7e-08 34.7 0.0 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDO68722.1 - 4.6e-05 23.0 0.2 0.12 11.8 0.0 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDO68722.1 - 0.00089 19.1 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CDO68722.1 - 0.00091 19.5 0.7 0.63 10.3 0.1 3.5 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.6 CDO68722.1 - 0.0024 16.6 0.0 0.17 10.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 CDO68722.1 - 0.025 14.8 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 CDO68722.1 - 0.03 14.5 0.3 0.55 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDO68722.1 - 0.031 14.8 0.0 0.096 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDO68722.1 - 0.034 13.4 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin E3_UbLigase_EDD PF11547.8 CDO68722.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD AAA_29 PF13555.6 CDO68722.1 - 0.11 12.3 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 CDO68722.1 - 0.11 12.7 0.2 0.46 10.7 0.2 2.0 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDO68722.1 - 0.13 11.9 0.0 0.62 9.7 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 CDO68722.1 - 0.17 12.0 0.0 7.1 6.7 0.0 3.0 4 0 0 4 4 4 0 AAA domain GTP_cyclohydroI PF01227.22 CDO68723.1 - 4.7e-75 250.9 0.2 5.8e-75 250.6 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CDO68723.1 - 0.0084 16.2 0.0 0.025 14.8 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 CDO68723.1 - 0.078 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain THOC2_N PF16134.5 CDO68724.1 - 9e-154 513.5 0.0 1.8e-153 512.5 0.0 1.5 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 CDO68724.1 - 2.3e-88 296.3 0.0 3.9e-88 295.6 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 CDO68724.1 - 5.9e-30 103.2 0.1 2e-29 101.5 0.1 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit TipAS PF07739.13 CDO68724.1 - 0.021 15.4 0.1 0.094 13.3 0.1 2.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Glyco_hydro_88 PF07470.13 CDO68725.1 - 2.5e-18 66.3 0.2 3.4e-18 65.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 CDO68725.1 - 0.0019 17.8 2.0 0.002 17.7 0.9 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 DUF3417 PF11897.8 CDO68725.1 - 0.07 13.6 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) MRC1 PF09444.10 CDO68726.1 - 1.1e-28 100.5 28.2 1.1e-28 100.5 28.2 5.2 5 1 0 5 5 5 1 MRC1-like domain AAA_18 PF13238.6 CDO68726.1 - 0.81 10.2 6.0 0.52 10.9 2.5 2.4 2 0 0 2 2 2 0 AAA domain Ribosomal_L3 PF00297.22 CDO68727.1 - 2e-188 625.9 9.9 2.3e-188 625.8 9.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PPR_2 PF13041.6 CDO68728.1 - 9.6e-09 35.3 4.2 2.1 8.6 0.0 6.6 5 1 2 7 7 7 3 PPR repeat family PPR_3 PF13812.6 CDO68728.1 - 2.9e-08 33.6 0.0 0.015 15.3 0.0 3.5 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.20 CDO68728.1 - 1.3e-05 25.1 6.7 4.3 7.8 0.0 6.8 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.7 CDO68728.1 - 0.00011 21.8 5.5 0.16 11.7 1.9 4.2 5 0 0 5 5 5 2 PPR repeat TPPII_N PF12583.8 CDO68728.1 - 0.04 14.5 0.3 0.1 13.2 0.3 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal AMMECR1 PF01871.17 CDO68729.1 - 1.2e-45 155.1 0.0 1.7e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Ras PF00071.22 CDO68730.1 - 4.9e-44 149.8 0.0 1.4e-43 148.3 0.0 1.6 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CDO68730.1 - 6.9e-33 113.4 0.0 9.5e-33 113.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO68730.1 - 1.4e-12 47.4 0.0 2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDO68730.1 - 1.9e-07 31.1 0.0 3.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDO68730.1 - 0.00029 20.3 0.1 0.00045 19.7 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDO68730.1 - 0.0008 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CDO68730.1 - 0.0055 17.0 0.2 0.015 15.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDO68730.1 - 0.014 15.3 0.0 0.052 13.5 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CDO68730.1 - 0.05 14.0 0.0 0.072 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Flg_new PF09479.10 CDO68730.1 - 0.084 13.1 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) NTPase_1 PF03266.15 CDO68730.1 - 0.087 12.7 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.9 CDO68730.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CDO68730.1 - 0.12 12.1 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDO68730.1 - 0.18 11.3 0.4 0.29 10.6 0.4 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribosomal_S7e PF01251.18 CDO68731.1 - 1.9e-87 291.8 2.5 2.1e-87 291.6 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_1 PF00515.28 CDO68732.1 - 5e-13 48.3 5.9 5.5e-07 29.1 1.4 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDO68732.1 - 1.1e-08 34.5 8.5 3e-05 23.8 1.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDO68732.1 - 9.5e-07 28.6 2.4 0.00055 20.0 0.7 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO68732.1 - 4.6e-06 27.0 1.9 0.001 19.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDO68732.1 - 2.4e-05 24.6 3.8 0.017 15.4 0.2 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDO68732.1 - 0.00024 21.6 0.8 0.042 14.7 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDO68732.1 - 0.00033 20.6 1.6 0.0046 17.0 0.4 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CDO68732.1 - 0.0017 19.0 2.3 1.1 10.0 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO68732.1 - 0.0026 18.0 1.1 0.012 15.8 0.3 2.1 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDO68732.1 - 0.0038 17.1 3.9 0.57 10.3 1.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO68732.1 - 0.025 14.3 1.9 4.1 7.2 0.1 3.1 2 1 1 3 3 3 0 TPR repeat MIT PF04212.18 CDO68732.1 - 0.048 13.7 0.2 16 5.6 0.0 2.7 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain RPT PF13446.6 CDO68732.1 - 0.1 12.6 0.1 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 A repeated domain in UCH-protein TPR_17 PF13431.6 CDO68732.1 - 0.12 12.8 2.8 0.56 10.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDO68732.1 - 0.35 11.6 6.9 1.5 9.6 0.6 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CCHC PF00098.23 CDO68733.1 - 0.00099 19.1 4.1 0.00099 19.1 4.1 3.1 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_6 PF15288.6 CDO68733.1 - 0.013 15.3 1.3 0.013 15.3 1.3 3.6 3 0 0 3 3 3 0 Zinc knuckle RVT_1 PF00078.27 CDO68734.1 - 3.1e-36 125.0 0.0 4.9e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO68734.1 - 1.6e-23 82.8 0.0 3.8e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDO68734.1 - 1.4e-11 44.4 1.5 3.1e-11 43.2 1.5 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.24 CDO68734.1 - 8.8e-09 35.7 0.0 2.6e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 CDO68734.1 - 0.0062 17.2 0.1 0.017 15.9 0.1 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PEMT PF04191.13 CDO68736.1 - 1.2e-53 180.0 9.4 4.6e-30 104.1 1.0 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase ApoLp-III PF07464.11 CDO68736.1 - 0.00097 19.3 0.1 0.0017 18.5 0.1 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) PP-binding PF00550.25 CDO68736.1 - 0.017 15.5 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Phosphopantetheine attachment site SKICH PF17751.1 CDO68736.1 - 0.019 15.5 0.0 0.058 14.0 0.0 1.8 1 1 0 1 1 1 0 SKICH domain RT_RNaseH PF17917.1 CDO68738.1 - 3.4e-30 104.4 0.0 7.9e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO68738.1 - 6.9e-21 74.2 0.0 1.4e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO68738.1 - 1.1e-15 57.8 0.0 2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDO68738.1 - 9.9e-15 54.4 0.1 2.5e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO68738.1 - 1.8e-12 47.5 0.0 6.7e-12 45.7 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 CDO68738.1 - 1.9e-09 37.4 0.0 3.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDO68738.1 - 5.6e-08 33.3 0.1 2.3e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO68738.1 - 4.2e-07 30.5 0.1 2.2e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 CDO68738.1 - 0.00051 19.8 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 CDO68738.1 - 0.012 15.8 0.2 0.041 14.2 0.2 2.0 1 0 0 1 1 1 0 Retrotransposon gag protein FAM199X PF15814.5 CDO68738.1 - 2.1 7.3 11.9 5.2 6.0 11.9 1.6 1 0 0 1 1 1 0 Protein family FAM199X Herpes_capsid PF06112.11 CDO68738.1 - 3.3 7.7 12.6 9.3 6.3 12.6 1.8 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein zf-CCHC PF00098.23 CDO68738.1 - 8.1 6.7 10.5 0.1 12.7 2.7 2.0 2 0 0 2 2 2 0 Zinc knuckle Zip PF02535.22 CDO68738.1 - 8.4 5.5 9.7 6.2 5.9 0.0 2.7 3 0 0 3 3 3 0 ZIP Zinc transporter UCH PF00443.29 CDO68739.1 - 5.6e-40 137.5 0.0 9.6e-40 136.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDO68739.1 - 4e-12 46.4 0.5 1.4e-09 38.0 0.5 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CDO68739.1 - 6.5e-08 32.2 0.0 1.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CDO68739.1 - 0.07 13.6 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF3886 PF13025.6 CDO68739.1 - 0.61 10.3 5.5 1.3 9.3 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Bap31 PF05529.12 CDO68740.1 - 6.9e-18 64.8 0.1 6.9e-18 64.8 0.1 1.5 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CDO68740.1 - 2.9e-12 46.4 8.4 2.9e-12 46.4 8.4 2.0 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Rab5-bind PF09311.11 CDO68740.1 - 0.028 13.8 5.8 0.033 13.6 5.8 1.1 1 0 0 1 1 1 0 Rabaptin-like protein RIC3 PF15361.6 CDO68740.1 - 0.055 13.9 3.8 0.032 14.6 2.3 1.6 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 CLN3 PF02487.17 CDO68740.1 - 0.11 11.5 0.4 0.12 11.4 0.4 1.0 1 0 0 1 1 1 0 CLN3 protein DUF2681 PF10883.8 CDO68740.1 - 0.37 11.2 7.7 1.5 9.3 7.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4337 PF14235.6 CDO68740.1 - 4.8 7.3 10.7 1.2 9.3 7.8 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) p450 PF00067.22 CDO68741.1 - 1e-62 212.4 0.0 1.2e-47 162.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 CDO68742.1 - 5.1e-66 223.3 0.0 8.2e-66 222.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_115 PF15979.5 CDO68743.1 - 8e-128 426.6 3.3 1.1e-127 426.2 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 CDO68743.1 - 3e-55 186.7 0.0 5.6e-55 185.8 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Aminotran_3 PF00202.21 CDO68744.1 - 3.1e-115 385.1 0.0 3.9e-115 384.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CDO68744.1 - 0.0011 18.3 0.0 0.0026 17.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CDO68744.1 - 0.077 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Fes1 PF08609.10 CDO68747.1 - 3.7e-24 85.4 0.5 1.3e-23 83.7 0.5 2.0 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 CDO68747.1 - 0.0027 18.1 0.6 0.026 14.9 0.1 2.8 1 1 1 2 2 2 1 HEAT repeats HEAT PF02985.22 CDO68747.1 - 0.083 13.2 0.6 3.6 8.1 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.6 CDO68747.1 - 0.12 12.9 0.8 21 5.8 0.0 3.7 2 1 1 3 3 3 0 HEAT-like repeat Arm PF00514.23 CDO68747.1 - 0.14 12.2 0.4 14 5.9 0.0 3.7 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 CDO68747.1 - 0.23 10.0 0.1 1.2 7.6 0.1 1.8 1 1 0 1 1 1 0 Adaptin N terminal region DHHC PF01529.20 CDO68748.1 - 1e-33 116.3 6.1 1.5e-33 115.7 6.1 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase TRP PF06011.12 CDO68748.1 - 0.29 9.8 3.7 0.42 9.3 3.7 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel FYVE PF01363.21 CDO68748.1 - 6.4 7.0 11.4 15 5.8 10.8 1.8 1 1 0 1 1 1 0 FYVE zinc finger Cullin_binding PF03556.15 CDO68750.1 - 8.1e-31 107.0 0.0 1.2e-21 77.4 0.0 2.3 1 1 1 2 2 2 2 Cullin binding UBA_4 PF14555.6 CDO68750.1 - 6.7e-09 35.4 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Retrotran_gag_2 PF14223.6 CDO68752.1 - 3.8e-27 94.6 0.0 4.8e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO68752.1 - 1.6e-07 31.1 2.7 2.7e-07 30.4 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDO68752.1 - 0.0062 16.5 0.3 0.016 15.1 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CDO68752.1 - 0.033 14.5 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_6 PF15288.6 CDO68752.1 - 0.12 12.2 1.1 0.23 11.4 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle MPP6 PF10175.9 CDO68753.1 - 3.1e-10 40.6 0.9 3.1e-10 40.6 0.9 1.9 2 1 0 2 2 2 1 M-phase phosphoprotein 6 Glyco_hydro_115 PF15979.5 CDO68754.1 - 1.8e-131 438.6 5.8 2.7e-131 438.0 5.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 ClpS PF02617.17 CDO68754.1 - 0.12 12.2 0.0 0.79 9.6 0.1 2.2 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS ASF1_hist_chap PF04729.13 CDO68755.1 - 4.6e-62 208.5 0.0 5.8e-62 208.2 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF3123 PF11321.8 CDO68755.1 - 0.036 14.7 0.0 0.051 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF1664 PF07889.12 CDO68756.1 - 0.017 15.1 0.3 0.042 13.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 CDO68756.1 - 0.11 12.8 19.4 0.077 13.2 9.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4201 PF13870.6 CDO68756.1 - 0.51 10.1 11.4 0.71 9.6 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4140 PF13600.6 CDO68756.1 - 0.68 10.4 12.1 2.2 8.7 0.1 3.1 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Golgin_A5 PF09787.9 CDO68756.1 - 0.99 8.8 14.2 0.28 10.6 8.7 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 FinO_N PF12602.8 CDO68756.1 - 1 9.7 9.1 0.24 11.7 1.2 3.0 3 1 0 3 3 3 0 Fertility inhibition protein N terminal Spc7 PF08317.11 CDO68756.1 - 1 8.2 15.0 0.51 9.2 2.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 CDO68756.1 - 1.2 8.5 14.1 0.77 9.1 3.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 CDO68756.1 - 2.3 8.4 15.3 0.19 11.8 1.1 2.7 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 ADIP PF11559.8 CDO68756.1 - 2.3 8.3 10.8 0.19 11.8 2.2 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding YlqD PF11068.8 CDO68756.1 - 2.4 8.6 7.8 1.8 8.9 0.8 2.5 1 1 1 2 2 2 0 YlqD protein TMPIT PF07851.13 CDO68756.1 - 2.4 7.3 4.2 1.3 8.1 0.3 1.9 1 1 1 2 2 2 0 TMPIT-like protein FapA PF03961.13 CDO68756.1 - 2.9 6.4 5.5 2.3 6.7 0.2 1.9 1 1 0 2 2 2 0 Flagellar Assembly Protein A DUF812 PF05667.11 CDO68756.1 - 2.9 6.6 11.9 6.2 5.6 11.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 CDO68756.1 - 3.5 6.1 7.4 15 4.1 7.4 1.8 1 1 0 1 1 1 0 AAA domain SHE3 PF17078.5 CDO68756.1 - 4.6 6.9 8.8 2.1 8.0 3.6 2.0 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 ZapB PF06005.12 CDO68756.1 - 5.9 7.4 21.1 0.71 10.4 1.2 3.2 2 1 0 2 2 2 0 Cell division protein ZapB DUF4407 PF14362.6 CDO68756.1 - 8.2 5.7 12.6 20 4.4 12.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 CDO68756.1 - 8.5 5.4 11.5 27 3.7 11.5 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NUDIX PF00293.28 CDO68758.1 - 5.2e-11 42.7 0.0 9.1e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain ANAPC4_WD40 PF12894.7 CDO68760.1 - 3.4e-12 46.5 0.6 0.00028 21.1 0.1 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDO68760.1 - 1.6e-05 25.6 5.9 0.0021 18.8 0.2 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 CDO68760.1 - 0.033 14.1 0.0 2.5 7.9 0.0 2.3 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.7 CDO68760.1 - 0.25 11.2 2.1 5.3 6.9 0.0 2.5 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term Glyco_hydro_16 PF00722.21 CDO68761.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3678 PF12435.8 CDO68761.1 - 4 6.9 5.9 1.7 8.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) RVT_2 PF07727.14 CDO68762.1 - 8.2e-55 186.1 0.0 1.2e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO68762.1 - 5.9e-12 45.8 0.0 1.5e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO68762.1 - 6.2e-09 35.6 0.0 1.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 CDO68762.1 - 0.00016 21.3 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 CDO68762.1 - 0.00031 20.5 0.1 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 CDO68762.1 - 0.045 13.8 0.6 0.11 12.6 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle ADH_zinc_N PF00107.26 CDO68763.1 - 1.3e-29 102.8 0.6 2e-29 102.2 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO68763.1 - 1.1e-21 78.2 0.1 1.9e-21 77.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO68763.1 - 1.8e-12 47.1 0.1 1.2e-11 44.4 0.1 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DAGK_cat PF00781.24 CDO68763.1 - 0.011 15.3 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain ADH_N_2 PF16884.5 CDO68763.1 - 0.028 14.3 0.0 0.078 12.9 0.0 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase NAD_kinase PF01513.21 CDO68763.1 - 0.045 13.0 0.1 0.069 12.3 0.1 1.2 1 0 0 1 1 1 0 ATP-NAD kinase DUF2117 PF09890.9 CDO68763.1 - 0.056 12.9 0.1 0.085 12.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) MFS_1 PF07690.16 CDO68764.1 - 2.9e-21 75.8 54.0 2.5e-14 53.0 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CDO68765.1 - 2.6e-11 43.1 45.5 2.5e-10 39.8 45.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Na_H_Exchanger PF00999.21 CDO68766.1 - 6.7e-75 252.3 36.3 8.4e-75 251.9 36.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2304 PF10066.9 CDO68766.1 - 3.3 8.0 7.3 5.6 7.2 0.5 3.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) 60KD_IMP PF02096.20 CDO68767.1 - 6e-22 78.3 5.6 7.1e-22 78.1 5.6 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein TPR_1 PF00515.28 CDO68768.1 - 2.1e-30 103.2 0.0 1.3e-06 28.0 0.1 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 CDO68768.1 - 9.2e-25 84.7 7.1 1.4e-05 24.8 0.1 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat DnaJ PF00226.31 CDO68768.1 - 7.8e-23 80.4 0.1 2e-22 79.1 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 CDO68768.1 - 8.2e-17 60.6 6.3 2.1e-09 36.9 0.1 6.7 7 0 0 7 7 7 2 TPR repeat TPR_12 PF13424.6 CDO68768.1 - 1e-16 61.0 6.1 0.00011 22.5 0.1 6.3 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDO68768.1 - 3.4e-15 55.9 8.8 1.9e-08 34.3 0.1 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDO68768.1 - 7.5e-12 45.7 19.2 2.1e-07 31.5 0.5 6.4 5 3 1 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDO68768.1 - 3.7e-11 42.3 0.2 0.011 15.9 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDO68768.1 - 4e-11 42.7 17.5 0.0018 18.9 0.0 7.9 4 3 5 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDO68768.1 - 5.8e-11 42.7 10.0 0.005 17.3 0.3 6.0 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDO68768.1 - 1e-06 28.4 4.5 0.35 11.0 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CDO68768.1 - 1.4e-06 27.6 2.9 0.85 9.1 0.0 4.6 4 0 0 4 4 4 2 SHNi-TPR TPR_17 PF13431.6 CDO68768.1 - 2.7e-05 24.2 1.7 0.95 10.0 0.1 6.0 7 0 0 7 7 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO68768.1 - 2.8e-05 24.3 3.2 0.79 10.0 0.0 4.9 3 3 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CDO68768.1 - 0.0018 17.5 5.9 0.11 11.6 0.1 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDO68768.1 - 0.0054 16.6 8.1 12 6.0 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 CDO68768.1 - 0.006 16.6 0.5 6.7 6.9 0.1 3.9 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 CDO68768.1 - 0.014 16.0 8.8 0.79 10.5 0.0 5.2 6 0 0 6 6 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDO68768.1 - 0.076 13.1 2.7 14 5.9 0.2 4.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CDO68768.1 - 0.4 11.1 5.9 8.6 6.8 0.0 3.0 2 1 1 3 3 2 0 Alkyl sulfatase dimerisation DUF202 PF02656.15 CDO68769.1 - 0.01 16.3 3.3 0.11 12.9 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) MtrG PF04210.13 CDO68769.1 - 0.094 12.6 0.7 0.28 11.1 0.7 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G SdpI PF13630.6 CDO68769.1 - 2.5 8.3 5.8 1.6 8.9 2.0 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family AA_permease_2 PF13520.6 CDO68771.1 - 2.7e-46 158.3 42.7 4.1e-46 157.7 42.7 1.2 1 0 0 1 1 1 1 Amino acid permease Trp_oprn_chp PF09534.10 CDO68771.1 - 0.3 10.8 3.7 0.92 9.3 2.8 2.4 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF962 PF06127.11 CDO68772.1 - 0.014 15.5 1.6 1.8 8.7 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF962) RTA1 PF04479.13 CDO68773.1 - 2.4e-50 171.0 0.5 2.5e-33 115.5 0.4 2.3 1 1 1 2 2 2 2 RTA1 like protein DUF4131 PF13567.6 CDO68773.1 - 0.73 9.5 5.5 1.5 8.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MARVEL PF01284.23 CDO68776.1 - 7.4e-06 26.1 11.3 1e-05 25.6 11.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain TssN PF17555.2 CDO68776.1 - 0.048 13.0 3.1 0.059 12.8 3.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Peptidase_U4 PF03419.13 CDO68776.1 - 0.16 11.2 3.4 0.18 11.0 3.4 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Profilin PF00235.19 CDO68778.1 - 1.1e-24 87.1 0.0 1.2e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Profilin DUF1365 PF07103.11 CDO68779.1 - 1.5e-51 175.4 0.0 3.5e-35 121.8 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1365) Membr_traf_MHD PF10540.9 CDO68780.1 - 4e-24 85.5 0.2 3e-21 76.2 0.2 2.8 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 CDO68780.1 - 1.4e-10 41.4 0.0 5.4e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 C2 domain Mem_trans PF03547.18 CDO68782.1 - 1.2e-26 93.1 1.3 2e-26 92.3 1.3 1.3 1 1 0 1 1 1 1 Membrane transport protein Trp_oprn_chp PF09534.10 CDO68782.1 - 0.22 11.3 1.5 0.49 10.2 1.5 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Polyketide_cyc2 PF10604.9 CDO68783.1 - 5.3e-08 33.2 0.0 7.6e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 CDO68783.1 - 0.0001 22.5 0.1 0.00013 22.2 0.1 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ECSIT PF06239.11 CDO68783.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway BAG PF02179.16 CDO68784.1 - 8.2e-05 23.0 0.0 8.2e-05 23.0 0.0 2.9 2 1 1 3 3 3 1 BAG domain NifQ PF04891.12 CDO68784.1 - 3.4 8.0 7.4 9.5 6.5 6.4 2.2 1 1 1 2 2 2 0 NifQ RNA_pol_I_A49 PF06870.12 CDO68785.1 - 2.2e-113 379.1 0.6 2.5e-113 378.9 0.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF2490 PF10677.9 CDO68785.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2490) SRI PF08236.11 CDO68786.1 - 1.7e-19 69.8 10.9 5.7e-19 68.1 10.9 2.0 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 CDO68786.1 - 7.4e-18 65.5 0.2 7.4e-18 65.5 0.2 3.5 2 2 0 2 2 2 1 SET domain Med26 PF08711.11 CDO68786.1 - 0.032 14.2 0.1 0.19 11.8 0.1 2.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Peptidase_S15 PF02129.18 CDO68786.1 - 0.051 13.2 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) ACC_epsilon PF13822.6 CDO68786.1 - 0.42 11.3 5.5 2.3 9.0 5.5 2.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Pkinase PF00069.25 CDO68787.1 - 0.00019 20.9 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDO68787.1 - 0.025 13.9 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDO68787.1 - 0.035 13.7 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 CDO68787.1 - 0.046 13.0 0.0 0.086 12.1 0.0 1.4 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO68787.1 - 0.075 11.8 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase GMC_oxred_N PF00732.19 CDO68788.1 - 6.3e-46 157.1 0.0 8e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO68788.1 - 1.9e-36 125.7 0.1 4.5e-36 124.5 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase BP28CT PF08146.12 CDO68790.1 - 1.2e-24 86.9 3.9 4.2e-24 85.2 2.4 2.7 2 0 0 2 2 2 1 BP28CT (NUC211) domain HEAT PF02985.22 CDO68790.1 - 0.00099 19.2 3.5 0.0054 16.9 0.3 4.1 3 0 0 3 3 3 1 HEAT repeat IFRD PF05004.13 CDO68790.1 - 0.0092 15.1 2.3 0.038 13.1 0.4 2.8 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Arm PF00514.23 CDO68790.1 - 0.13 12.4 2.6 15 5.8 0.1 4.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat U3snoRNP10 PF12397.8 CDO68791.1 - 3e-10 40.5 4.1 3e-10 40.5 4.1 3.2 3 1 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 TetR_C_31 PF17940.1 CDO68791.1 - 0.2 11.9 8.1 25 5.1 0.4 3.9 2 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 CDO68792.1 - 6.2e-37 127.4 0.0 8.9e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO68792.1 - 4e-28 98.4 0.0 5.9e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO68792.1 - 1.3e-06 27.9 0.0 2.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PBD PF00786.28 CDO68792.1 - 1.4e-05 25.3 0.0 3.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain HMG_box_2 PF09011.10 CDO68793.1 - 1.2e-06 29.0 1.4 3.1e-06 27.7 1.4 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CDO68793.1 - 0.00013 22.3 1.3 0.00079 19.8 1.0 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box Ku_PK_bind PF08785.11 CDO68793.1 - 0.12 12.5 0.5 0.52 10.5 0.1 2.1 2 0 0 2 2 2 0 Ku C terminal domain like DUF2299 PF10061.9 CDO68793.1 - 0.15 11.8 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) APG6_N PF17675.1 CDO68793.1 - 0.39 11.2 8.5 0.058 13.9 3.9 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region WD40 PF00400.32 CDO68795.1 - 4.6e-11 43.1 0.4 4e-05 24.3 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1604 PF07713.13 CDO68796.1 - 1.5e-21 76.0 0.0 1.5e-21 76.0 0.0 3.9 5 0 0 5 5 5 1 Protein of unknown function (DUF1604) G-patch PF01585.23 CDO68796.1 - 6.3e-07 29.2 0.2 6.3e-07 29.2 0.2 2.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CDO68796.1 - 0.032 14.3 0.0 0.032 14.3 0.0 3.2 4 0 0 4 4 4 0 G-patch domain AA_permease PF00324.21 CDO68798.1 - 1.4e-127 426.2 31.9 1.6e-127 426.0 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CDO68798.1 - 5.9e-35 120.9 38.3 7.3e-35 120.6 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_23 PF13489.6 CDO68799.1 - 4e-11 43.0 0.0 5.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO68799.1 - 9.2e-11 42.3 0.0 1.7e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO68799.1 - 1.5e-10 41.7 0.0 4.2e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO68799.1 - 2.3e-07 31.4 0.0 4.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO68799.1 - 6.7e-05 22.7 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CDO68799.1 - 0.0044 18.0 0.0 0.0085 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDO68799.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RhoGEF PF00621.20 CDO68800.1 - 7.6e-71 238.1 1.0 1.8e-35 122.9 0.1 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 CDO68800.1 - 3.8e-62 210.4 0.0 5.7e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 CDO68800.1 - 2.4e-18 66.6 0.0 7e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 CDO68800.1 - 4.7e-05 23.4 0.0 0.00023 21.2 0.0 2.2 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 CDO68800.1 - 0.0014 19.1 0.0 0.0045 17.5 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 CDO68800.1 - 0.018 14.8 0.1 0.19 11.5 0.1 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain PH_16 PF17838.1 CDO68800.1 - 0.036 13.9 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 PH domain DRTGG PF07085.12 CDO68802.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 DRTGG domain Acetyltransf_6 PF13480.7 CDO68803.1 - 0.053 13.7 0.1 13 5.9 0.0 2.3 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain FAM199X PF15814.5 CDO68803.1 - 4.4 6.3 10.2 24 3.8 11.0 1.7 2 0 0 2 2 2 0 Protein family FAM199X SQHop_cyclase_N PF13249.6 CDO68805.1 - 1.6e-11 43.8 0.0 2.3e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Squalene-hopene cyclase N-terminal domain Acetyltransf_6 PF13480.7 CDO68806.1 - 0.1 12.7 0.2 15 5.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FlxA PF14282.6 CDO68808.1 - 0.01 15.8 0.9 0.013 15.4 0.9 1.2 1 0 0 1 1 1 0 FlxA-like protein Spectrin PF00435.21 CDO68808.1 - 0.01 16.3 2.4 0.015 15.8 2.4 1.2 1 0 0 1 1 1 0 Spectrin repeat RasGAP_C PF03836.15 CDO68808.1 - 0.027 14.6 0.8 0.035 14.3 0.8 1.1 1 0 0 1 1 1 0 RasGAP C-terminus She9_MDM33 PF05546.11 CDO68808.1 - 0.055 13.3 4.1 0.071 12.9 4.1 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family DUF4407 PF14362.6 CDO68808.1 - 0.062 12.7 0.5 0.064 12.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIN_2 PF10130.9 CDO68808.1 - 0.089 13.0 0.5 0.12 12.6 0.5 1.1 1 0 0 1 1 1 0 PIN domain CENP-Q PF13094.6 CDO68808.1 - 0.16 12.2 10.6 0.24 11.6 10.6 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SLATT_5 PF18160.1 CDO68808.1 - 0.23 10.8 1.4 0.27 10.5 1.4 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Integrase_H2C2 PF17921.1 CDO68809.1 - 1.2e-17 63.7 0.3 3.7e-17 62.2 0.3 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CDO68809.1 - 2.1e-06 27.8 0.1 6e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 CDO68809.1 - 3.9e-05 23.5 0.0 3.9e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 CDO68809.1 - 0.041 14.1 0.0 0.21 11.8 0.0 2.2 1 1 1 2 2 2 0 Integrase core domain zf-RVT PF13966.6 CDO68810.1 - 7.5e-07 29.8 0.0 1.2e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RT_RNaseH PF17917.1 CDO68811.1 - 7.8e-30 103.3 0.0 1.5e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO68811.1 - 1.5e-29 102.0 0.1 4.1e-29 100.6 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO68811.1 - 1.5e-19 70.4 0.0 2.3e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO68811.1 - 4.8e-06 26.8 0.2 1.9e-05 24.9 0.2 2.1 1 1 0 1 1 1 1 RNase H Retrotrans_gag PF03732.17 CDO68812.1 - 7.1e-12 45.5 0.1 2e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO68812.1 - 3.1e-08 33.5 0.0 6.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) FAM199X PF15814.5 CDO68812.1 - 0.84 8.6 7.9 1.7 7.6 7.9 1.4 1 0 0 1 1 1 0 Protein family FAM199X DDE_Tnp_4 PF13359.6 CDO68813.1 - 4.6e-07 29.6 0.0 5.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO68813.1 - 0.0057 16.3 0.0 0.0071 16.0 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Acetyltransf_6 PF13480.7 CDO68814.1 - 0.05 13.7 0.2 9.1 6.4 0.0 2.2 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain SQHop_cyclase_N PF13249.6 CDO68815.1 - 1.3e-33 116.4 0.1 3.2e-33 115.1 0.1 1.5 1 1 0 1 1 1 1 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 CDO68815.1 - 3.2e-10 39.6 0.7 4.5e-08 32.7 0.0 2.7 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CDO68815.1 - 0.0066 15.6 0.0 0.029 13.5 0.0 1.8 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain AurF PF11583.8 CDO68815.1 - 1.7 7.9 2.8 2.4 7.3 2.8 1.2 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF SQHop_cyclase_C PF13243.6 CDO68816.1 - 0.00039 19.6 0.0 0.00048 19.3 0.0 1.1 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain DUF3060 PF11259.8 CDO68817.1 - 0.00024 20.7 11.6 0.25 11.1 0.0 5.0 3 1 1 4 4 4 3 Protein of unknown function (DUF3060) Cellulase PF00150.18 CDO68818.1 - 0.00017 21.1 0.1 0.08 12.4 0.0 2.7 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Lipase_3 PF01764.25 CDO68819.1 - 3.8e-24 85.2 0.0 5.5e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDO68819.1 - 0.0019 18.8 0.1 0.0023 18.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CDO68819.1 - 0.047 13.3 0.1 0.074 12.7 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 CDO68819.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DAGAT PF03982.13 CDO68822.1 - 4.4e-89 298.3 0.0 8.4e-89 297.4 0.0 1.3 1 1 0 1 1 1 1 Diacylglycerol acyltransferase AAA PF00004.29 CDO68823.1 - 4.3e-97 321.6 0.0 1.9e-47 161.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDO68823.1 - 7.2e-26 89.7 7.3 1.3e-12 47.3 0.9 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CDO68823.1 - 6.5e-22 77.5 0.4 3.6e-21 75.1 0.3 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CDO68823.1 - 2.8e-14 53.2 0.0 6e-06 26.1 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDO68823.1 - 6.8e-14 52.3 0.0 1.6e-07 31.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CDO68823.1 - 7.7e-12 45.6 0.0 6.1e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 CDO68823.1 - 1.2e-11 44.2 0.0 2.9e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 CDO68823.1 - 1.4e-11 44.5 0.6 2.4e-05 24.3 0.1 3.9 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDO68823.1 - 7.3e-11 42.7 0.1 0.0017 18.8 0.0 4.4 3 2 0 3 3 2 2 AAA ATPase domain TIP49 PF06068.13 CDO68823.1 - 1.6e-09 37.4 0.1 0.0014 17.9 0.0 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 CDO68823.1 - 3.5e-09 37.0 0.3 0.021 15.1 0.0 4.1 3 2 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 CDO68823.1 - 3.7e-07 29.8 0.3 0.03 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CDO68823.1 - 5.3e-07 30.0 0.0 0.022 15.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 CDO68823.1 - 7.1e-07 29.3 0.0 0.014 15.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 CDO68823.1 - 8e-07 29.7 0.0 0.04 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CDO68823.1 - 8.3e-07 28.9 0.0 0.023 14.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 CDO68823.1 - 1.7e-06 27.5 0.6 0.56 9.5 0.0 3.4 3 0 0 3 3 3 2 KaiC Vps4_C PF09336.10 CDO68823.1 - 2.7e-06 27.3 1.0 7.6e-05 22.6 0.1 3.1 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.17 CDO68823.1 - 4.1e-06 26.1 0.2 0.013 14.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 CDO68823.1 - 4.2e-06 26.6 0.1 0.081 12.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 CDO68823.1 - 5.3e-06 26.1 0.1 0.023 14.2 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 CDO68823.1 - 6.6e-06 25.8 1.3 0.75 9.3 0.0 3.6 2 2 0 3 3 3 2 AAA domain DUF815 PF05673.13 CDO68823.1 - 7.7e-06 25.3 0.0 0.0038 16.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 CDO68823.1 - 8.7e-06 25.5 0.0 0.22 11.2 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 CDO68823.1 - 1.5e-05 25.5 0.0 0.054 14.0 0.0 3.7 2 1 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 CDO68823.1 - 1.9e-05 24.9 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 CDO68823.1 - 2e-05 24.5 0.0 0.099 12.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_17 PF13207.6 CDO68823.1 - 0.00011 22.6 0.0 0.5 10.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 CDO68823.1 - 0.00013 22.0 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 CDO68823.1 - 0.00017 21.1 0.4 0.44 10.0 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 CDO68823.1 - 0.00019 21.3 0.0 0.79 9.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CDO68823.1 - 0.00028 21.0 0.0 0.086 12.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CDO68823.1 - 0.00034 20.5 0.9 1 9.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.9 CDO68823.1 - 0.00057 19.2 0.0 1.1 8.4 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 CDO68823.1 - 0.00059 19.8 0.2 2 8.3 0.0 3.1 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea Molydop_binding PF01568.21 CDO68823.1 - 0.0012 18.8 0.1 0.0029 17.6 0.1 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain AAA_30 PF13604.6 CDO68823.1 - 0.0018 18.0 0.8 2 8.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 CDO68823.1 - 0.0019 18.0 0.0 0.8 9.4 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 CDO68823.1 - 0.0025 17.7 0.3 1.2 9.0 0.0 2.9 3 0 0 3 3 2 1 NACHT domain Zeta_toxin PF06414.12 CDO68823.1 - 0.0027 17.0 0.0 1.6 8.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin UFD1 PF03152.14 CDO68823.1 - 0.0029 17.1 0.0 0.0075 15.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Sigma54_activ_2 PF14532.6 CDO68823.1 - 0.0043 17.2 0.0 4.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 CDO68823.1 - 0.0043 16.3 0.0 0.63 9.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.6 CDO68823.1 - 0.0051 17.2 2.0 3.9 7.8 0.0 3.5 3 1 0 4 4 3 0 AAA domain IPT PF01745.16 CDO68823.1 - 0.0087 15.5 0.1 2.4 7.5 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase T2SSE PF00437.20 CDO68823.1 - 0.03 13.4 0.0 1.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 CDO68823.1 - 0.043 13.5 0.0 8.3 6.1 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 CDO68823.1 - 0.057 13.1 0.0 1.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) NTPase_1 PF03266.15 CDO68823.1 - 0.077 12.9 0.5 15 5.5 0.0 3.4 3 0 0 3 3 3 0 NTPase PIF1 PF05970.14 CDO68823.1 - 0.22 10.7 0.3 18 4.4 0.0 3.0 3 0 0 3 3 3 0 PIF1-like helicase CAP_GLY PF01302.25 CDO68824.1 - 1.7e-28 98.4 1.2 2.8e-28 97.7 1.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 CDO68824.1 - 7.3e-20 71.2 0.0 8.1e-13 48.6 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-like domain 4HBT_2 PF13279.6 CDO68825.1 - 9.5e-14 51.9 0.0 1.5e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 CDO68825.1 - 8.4e-06 26.1 0.1 2.2e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 CDO68825.1 - 0.00066 19.0 0.1 0.026 13.8 0.0 2.2 2 0 0 2 2 2 2 Acyl-ACP thioesterase zf-C3HC4_3 PF13920.6 CDO68826.1 - 9.1e-09 35.0 7.7 9.1e-09 35.0 7.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO68826.1 - 2.1e-08 33.9 8.4 2.1e-08 33.9 8.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDO68826.1 - 5.5e-08 32.8 9.0 5.5e-08 32.8 9.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CDO68826.1 - 1.5e-07 31.3 4.2 1.5e-07 31.3 4.2 3.5 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDO68826.1 - 4.9e-07 30.0 9.6 4.9e-07 30.0 9.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDO68826.1 - 9.3e-07 28.6 9.6 9.3e-07 28.6 9.6 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO68826.1 - 2.8e-05 24.0 9.2 2.8e-05 24.0 9.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDO68826.1 - 0.00039 20.2 7.1 0.00039 20.2 7.1 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CDO68826.1 - 0.0062 16.3 3.5 0.0062 16.3 3.5 2.6 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain Phage_DsbA PF11126.8 CDO68826.1 - 0.0077 16.4 0.5 0.013 15.7 0.5 1.3 1 0 0 1 1 1 1 Transcriptional regulator DsbA zf-RING_11 PF17123.5 CDO68826.1 - 0.79 9.5 12.3 0.072 12.9 5.2 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_6 PF14835.6 CDO68826.1 - 1 9.3 14.2 0.08 12.8 6.2 2.8 3 1 0 3 3 3 0 zf-RING of BARD1-type protein FYVE PF01363.21 CDO68826.1 - 2.2 8.5 7.1 1.9 8.7 2.8 2.8 2 1 1 3 3 3 0 FYVE zinc finger zf-RING_10 PF16685.5 CDO68826.1 - 8.3 6.6 11.9 0.96 9.6 5.9 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 Ribosomal_L19e PF01280.20 CDO68827.1 - 4.3 7.4 16.7 0.55 10.3 0.4 4.0 4 1 0 4 4 4 0 Ribosomal protein L19e Filaggrin PF03516.13 CDO68828.1 - 0.59 10.9 0.1 0.59 10.9 0.1 3.7 4 0 0 4 4 4 0 Filaggrin Ran_BP1 PF00638.18 CDO68829.1 - 2.4e-11 43.9 0.0 2.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 RanBP1 domain Tape_meas_lam_C PF09718.10 CDO68829.1 - 0.18 11.9 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Thioredoxin PF00085.20 CDO68830.1 - 0.0015 18.5 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin DUF4485 PF14846.6 CDO68831.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) STT3 PF02516.14 CDO68832.1 - 1.5e-145 485.8 36.4 6.5e-138 460.7 34.1 2.1 1 1 1 2 2 2 2 Oligosaccharyl transferase STT3 subunit UBX PF00789.20 CDO68833.1 - 9.6e-12 44.9 0.4 3.7e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 UBX domain zf-C2H2_2 PF12756.7 CDO68833.1 - 0.016 15.5 0.3 0.016 15.5 0.3 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF572 PF04502.13 CDO68833.1 - 0.096 12.3 15.8 0.13 11.8 15.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-C2H2 PF00096.26 CDO68833.1 - 0.13 12.7 0.2 0.26 11.8 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO68833.1 - 0.2 12.2 0.5 0.45 11.0 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger double domain Asp-B-Hydro_N PF05279.11 CDO68833.1 - 2.1 8.4 21.4 3 7.9 21.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DivIC PF04977.15 CDO68834.1 - 1.3 8.9 7.2 0.085 12.6 0.8 2.4 3 0 0 3 3 3 0 Septum formation initiator APG6_N PF17675.1 CDO68834.1 - 1.3 9.6 12.5 0.11 13.0 6.8 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region APH PF01636.23 CDO68835.1 - 2.7e-33 115.9 0.0 3.6e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO68835.1 - 0.00089 18.9 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 CDO68835.1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase GMC_oxred_N PF00732.19 CDO68836.1 - 9.3e-34 117.1 0.0 8e-26 91.1 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO68836.1 - 3.6e-25 89.2 0.1 1.3e-24 87.3 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CDO68836.1 - 2.4e-05 23.6 0.4 4e-05 22.8 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CDO68836.1 - 0.0011 18.1 0.1 0.025 13.7 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CDO68836.1 - 0.067 12.8 1.8 0.15 11.6 0.8 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CDO68836.1 - 0.095 11.5 0.8 0.15 10.8 0.8 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 CDO68836.1 - 0.15 12.3 0.4 0.48 10.7 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Aminotran_1_2 PF00155.21 CDO68837.1 - 5.6e-65 219.9 0.0 6.6e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CDO68837.1 - 7.4e-09 35.4 0.0 3.2e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CDO68837.1 - 9.8e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CDO68837.1 - 0.00015 20.4 0.1 0.00029 19.5 0.1 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CDO68837.1 - 0.00047 19.2 0.0 0.17 10.8 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V OKR_DC_1 PF01276.20 CDO68837.1 - 0.24 10.1 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain GPI-anchored PF10342.9 CDO68838.1 - 6.2e-05 23.7 0.9 6.2e-05 23.7 0.9 2.4 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 CDO68838.1 - 5.8 6.0 14.5 7.3 5.7 14.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Aldo_ket_red PF00248.21 CDO68839.1 - 2.4e-28 99.2 0.0 1.3e-17 63.9 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Ish1 PF10281.9 CDO68839.1 - 0.14 12.5 0.1 40 4.6 0.0 2.9 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein GPI-anchored PF10342.9 CDO68841.1 - 4.3e-06 27.4 0.0 6.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RNase_H2_suC PF08615.11 CDO68842.1 - 5.3e-19 68.8 0.0 6.7e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Pkinase_fungal PF17667.1 CDO68843.1 - 3.3e-20 72.2 0.6 1.3e-16 60.4 0.1 2.4 1 1 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 CDO68843.1 - 0.00053 19.4 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CDO68843.1 - 0.011 15.6 0.2 0.025 14.5 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_6 PF12697.7 CDO68845.1 - 1.8e-06 28.8 4.2 2.7e-06 28.2 4.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDO68845.1 - 7.8e-05 22.4 0.0 0.0002 21.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Vsr PF03852.15 CDO68845.1 - 0.12 12.2 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Ytp1 PF10355.9 CDO68846.1 - 9e-60 202.2 14.8 5.8e-58 196.3 14.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) SdpI PF13630.6 CDO68846.1 - 0.44 10.7 20.2 1.3 9.2 0.7 4.6 5 0 0 5 5 5 0 SdpI/YhfL protein family zf-C3HC4_3 PF13920.6 CDO68847.1 - 6.6e-09 35.5 6.6 1.1e-08 34.8 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO68847.1 - 4.9e-08 32.7 10.0 7.8e-08 32.1 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDO68847.1 - 3.3e-07 30.3 11.2 5.5e-07 29.6 11.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CDO68847.1 - 5e-07 29.9 8.8 7.9e-07 29.3 8.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CDO68847.1 - 8.9e-07 28.8 8.3 1.4e-06 28.1 8.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDO68847.1 - 1.1e-06 28.5 6.8 4.1e-06 26.7 7.2 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDO68847.1 - 2.3e-06 27.3 9.9 4.2e-06 26.5 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDO68847.1 - 0.00021 21.1 9.0 0.00021 21.1 9.0 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Syntaxin_2 PF14523.6 CDO68847.1 - 0.011 16.1 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 Syntaxin-like protein zf-MIZ PF02891.20 CDO68847.1 - 0.037 13.8 6.2 0.067 13.0 6.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger HALZ PF02183.18 CDO68847.1 - 0.093 13.0 3.2 1.6 9.0 0.5 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-RING_4 PF14570.6 CDO68847.1 - 0.18 11.6 6.0 0.35 10.7 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 CDO68847.1 - 0.85 9.8 5.8 1.7 8.8 5.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 HypA PF01155.19 CDO68847.1 - 1.1 9.3 4.6 2.4 8.2 4.6 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Steroid_dh PF02544.16 CDO68848.1 - 8.3e-25 87.5 5.3 5.7e-15 55.6 5.8 3.2 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CDO68848.1 - 1.5e-06 28.0 1.9 2.3e-05 24.0 1.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Pkinase_fungal PF17667.1 CDO68849.1 - 1.7e-15 56.8 0.0 4.4e-15 55.4 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO68850.1 - 3.5e-19 68.9 0.0 5.1e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CDO68850.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Zeta_toxin PF06414.12 CDO68851.1 - 0.097 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KAP_NTPase PF07693.14 CDO68851.1 - 0.21 10.8 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ubiquitin PF00240.23 CDO68852.1 - 1.5e-06 27.8 0.2 8.3e-06 25.5 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 CDO68852.1 - 2.2e-05 24.8 0.1 9.1e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 CDO68852.1 - 0.0085 15.9 0.1 0.059 13.2 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.18 CDO68852.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain RAWUL PF16207.5 CDO68852.1 - 0.013 16.1 0.0 0.015 15.9 0.0 1.1 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like DUF4431 PF14485.6 CDO68852.1 - 0.046 13.5 0.0 3.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) Amidohydro_1 PF01979.20 CDO68853.1 - 1.5e-29 103.4 1.8 4.9e-28 98.4 1.8 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDO68853.1 - 1.2e-07 31.6 1.5 0.00041 19.9 0.0 2.6 2 1 0 3 3 3 2 Amidohydrolase family Molybdopterin_N PF18364.1 CDO68853.1 - 0.3 11.2 1.2 3.4 7.7 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin oxidoreductase N-terminal domain HSP70 PF00012.20 CDO68854.1 - 3.6e-264 877.5 15.2 4.1e-264 877.3 15.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDO68854.1 - 2.7e-14 52.7 11.0 1.6e-13 50.2 1.9 3.2 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 CDO68854.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CDO68854.1 - 0.0015 18.9 6.7 0.31 11.5 0.2 3.9 3 1 0 3 3 3 2 Cell division protein FtsA DMRL_synthase PF00885.19 CDO68854.1 - 0.019 14.8 0.4 0.12 12.2 0.1 2.2 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase GLE1 PF07817.13 CDO68854.1 - 0.13 11.4 1.0 3.7 6.7 0.8 2.2 2 0 0 2 2 2 0 GLE1-like protein SMBP PF16785.5 CDO68854.1 - 5.2 7.3 9.5 1.5 9.0 5.8 2.1 2 0 0 2 2 2 0 Small metal-binding protein MIF4G PF02854.19 CDO68855.1 - 1.4e-56 191.5 0.1 1.4e-56 191.5 0.1 1.8 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 CDO68855.1 - 2.3e-20 72.5 0.0 6.6e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 CDO68855.1 - 2.5e-10 40.4 0.5 6.5e-10 39.0 0.2 1.9 2 0 0 2 2 2 1 MA3 domain Pkinase_fungal PF17667.1 CDO68857.1 - 3.3e-53 180.9 0.0 2.4e-51 174.8 0.0 2.9 2 1 0 2 2 2 1 Fungal protein kinase AF-4 PF05110.13 CDO68857.1 - 0.61 8.1 17.3 0.85 7.6 17.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pkinase_fungal PF17667.1 CDO68858.1 - 6e-12 45.1 0.0 7.2e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase SAP PF02037.27 CDO68859.1 - 0.009 15.7 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 2 SAP domain DUF3632 PF12311.8 CDO68860.1 - 2.2e-25 90.1 0.0 3e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Cu_bind_like PF02298.17 CDO68861.1 - 0.00079 19.4 4.1 0.29 11.2 0.1 3.6 2 2 0 2 2 2 2 Plastocyanin-like domain Copper-bind PF00127.20 CDO68861.1 - 0.008 16.6 6.7 3.8 8.0 0.2 3.8 2 2 1 3 3 3 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 CDO68861.1 - 0.021 14.9 0.4 0.43 10.7 0.1 2.7 2 1 0 2 2 2 0 Cupredoxin-like domain MUG113 PF13455.6 CDO68862.1 - 1.9e-13 50.8 0.0 6.3e-13 49.2 0.0 2.0 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 CDO68862.1 - 4.7e-09 36.7 0.2 6.8e-08 33.0 0.0 2.8 3 0 0 3 3 3 1 T5orf172 domain AAA_32 PF13654.6 CDO68862.1 - 0.23 10.2 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain dsDNA_bind PF01984.20 CDO68863.1 - 2.1e-15 56.9 4.9 2.6e-09 37.3 2.1 2.0 1 1 1 2 2 2 2 Double-stranded DNA-binding domain zf-RING_4 PF14570.6 CDO68864.1 - 5e-21 74.2 11.7 8.4e-21 73.5 11.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CDO68864.1 - 5.1e-06 26.2 9.2 8.6e-06 25.5 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CDO68864.1 - 0.00033 20.4 0.0 0.001 18.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 CDO68864.1 - 0.0053 17.1 12.7 0.0096 16.2 12.7 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CDO68864.1 - 0.0095 15.8 10.5 0.6 10.0 11.2 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 CDO68864.1 - 0.092 12.7 4.3 0.17 11.8 4.3 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.6 CDO68864.1 - 0.38 10.6 12.8 0.72 9.7 12.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO68864.1 - 0.49 10.3 13.2 0.83 9.6 13.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MYND PF01753.18 CDO68868.1 - 3.1e-11 43.2 6.8 5e-11 42.5 6.8 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CDO68868.1 - 0.032 14.5 4.7 0.06 13.7 4.7 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Sas10_Utp3 PF04000.15 CDO68869.1 - 1.7e-12 47.8 0.0 3.3e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Med2 PF11214.8 CDO68869.1 - 0.18 12.0 1.8 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 2 GEN1_C PF18380.1 CDO68869.1 - 0.3 12.0 7.9 1.3 9.9 0.3 2.8 3 0 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain UCH_1 PF13423.6 CDO68870.1 - 1.1e-77 261.8 0.0 7e-76 255.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 CDO68870.1 - 2.3e-21 77.0 0.0 3.9e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 CDO68870.1 - 0.00027 20.5 0.0 0.00059 19.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 CDO68870.1 - 0.07 13.4 0.0 39 4.7 0.0 3.9 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDO68870.1 - 0.09 13.7 1.4 69 4.6 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Arginase PF00491.21 CDO68871.1 - 1.8e-73 247.5 0.0 3.3e-44 151.5 0.0 2.1 2 0 0 2 2 2 2 Arginase family DUF3535 PF12054.8 CDO68873.1 - 8.8e-101 338.3 0.0 2.5e-100 336.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 CDO68873.1 - 6.8e-67 225.6 0.2 1.2e-66 224.8 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDO68873.1 - 3e-17 63.0 0.0 6.9e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 CDO68873.1 - 6.1e-10 38.5 17.4 0.14 12.4 0.0 8.9 11 0 0 11 11 9 4 HEAT repeat ResIII PF04851.15 CDO68873.1 - 4.3e-05 23.6 0.0 0.00011 22.3 0.0 1.7 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit HEAT_EZ PF13513.6 CDO68873.1 - 0.00022 21.6 8.5 18 6.0 0.0 7.6 8 0 0 8 8 7 0 HEAT-like repeat DUF3385 PF11865.8 CDO68873.1 - 0.0009 19.2 0.1 0.0034 17.3 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 CDO68873.1 - 0.0024 18.2 5.0 3 8.3 0.0 6.0 6 0 0 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.7 CDO68873.1 - 0.0037 17.8 0.0 1.7 9.3 0.0 2.9 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 CDO68873.1 - 0.041 13.0 0.0 0.084 12.0 0.0 1.5 1 0 0 1 1 1 0 Dopey, N-terminal CLASP_N PF12348.8 CDO68873.1 - 0.075 12.6 0.2 1.1 8.7 0.1 2.9 2 1 0 2 2 2 0 CLASP N terminal Cnd1 PF12717.7 CDO68873.1 - 0.19 11.7 1.3 40 4.2 0.0 3.9 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Cupin_8 PF13621.6 CDO68874.1 - 2.8e-36 125.6 0.0 4.9e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CDO68874.1 - 4.7e-06 26.3 0.0 7.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 CDO68874.1 - 6.3e-05 22.6 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 CDO68874.1 - 0.018 15.4 0.1 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_1 PF00190.22 CDO68874.1 - 0.02 14.5 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 CDO68874.1 - 0.027 14.4 0.2 0.058 13.3 0.2 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain FAD_binding_2 PF00890.24 CDO68875.1 - 7.2e-103 344.9 7.3 2.1e-94 316.9 1.1 2.1 1 1 1 2 2 2 2 FAD binding domain Succ_DH_flav_C PF02910.20 CDO68875.1 - 1e-44 151.6 1.2 1.5e-44 151.0 1.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 CDO68875.1 - 6.2e-06 25.5 1.1 0.0084 15.2 2.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 CDO68875.1 - 2.3e-05 23.7 0.2 0.023 13.9 0.0 2.7 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.14 CDO68875.1 - 0.00054 19.3 1.5 0.0016 17.7 0.6 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDO68875.1 - 0.0024 17.2 0.1 0.0042 16.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CDO68875.1 - 0.025 13.7 0.1 0.051 12.6 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein TAL_FSA PF00923.19 CDO68875.1 - 0.031 13.6 0.1 0.054 12.8 0.1 1.3 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase DAO PF01266.24 CDO68875.1 - 0.035 13.7 1.4 0.13 11.8 1.4 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CDO68875.1 - 0.087 11.5 1.8 0.37 9.4 0.6 2.5 3 1 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 CDO68875.1 - 0.98 8.6 2.4 2.4 7.3 1.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RabGAP-TBC PF00566.18 CDO68876.1 - 1.1e-28 100.4 0.0 1.1e-14 54.7 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain LCE6A PF15858.5 CDO68876.1 - 3.8 8.3 5.5 16 6.3 5.5 2.1 1 0 0 1 1 1 0 Late cornified envelope protein 6A family Cullin_binding PF03556.15 CDO68877.1 - 3.4e-28 98.5 0.6 4.1e-28 98.2 0.6 1.1 1 0 0 1 1 1 1 Cullin binding MSV199 PF10553.9 CDO68877.1 - 0.036 14.3 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 MSV199 domain DUF659 PF04937.15 CDO68878.1 - 5e-14 52.4 0.0 9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CDO68878.1 - 4.4e-10 39.2 0.0 9.5e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2603 PF10788.9 CDO68878.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) FeS_assembly_P PF01883.19 CDO68879.1 - 4.1e-09 36.5 0.0 6.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Dynamin_M PF01031.20 CDO68881.1 - 6.1e-104 347.2 0.0 1.4e-103 346.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CDO68881.1 - 2.9e-55 186.9 0.0 6e-55 185.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CDO68881.1 - 4.9e-28 97.1 5.3 4.9e-28 97.1 5.3 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CDO68881.1 - 2.9e-05 24.1 0.1 0.00021 21.3 0.1 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 CDO68881.1 - 0.37 10.4 3.2 8.6 6.0 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain CAF1A PF12253.8 CDO68882.1 - 0.051 13.7 0.3 0.073 13.3 0.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A GHL13 PF14883.6 CDO68883.1 - 0.022 13.9 0.1 0.025 13.6 0.1 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 Med1 PF10744.9 CDO68884.1 - 0.021 13.9 0.0 1.2 8.1 0.0 2.7 2 1 0 2 2 2 0 Mediator of RNA polymerase II transcription subunit 1 Glyco_hydro_88 PF07470.13 CDO68886.1 - 1.3e-09 37.6 0.5 2e-09 37.0 0.5 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 tRNA-synt_1b PF00579.25 CDO68887.1 - 3.1e-17 62.8 0.0 9.5e-17 61.2 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TBP PF00352.21 CDO68888.1 - 3.4e-66 219.2 0.2 3e-32 110.4 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CDO68888.1 - 0.03 14.4 8.8 0.39 10.9 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3378) Spt20 PF12090.8 CDO68888.1 - 0.09 12.4 16.1 0.13 11.8 16.1 1.2 1 0 0 1 1 1 0 Spt20 family DUF4295 PF14128.6 CDO68888.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) SOG2 PF10428.9 CDO68888.1 - 1.5 7.9 14.8 1.9 7.6 14.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 CDO68888.1 - 2 8.3 13.9 2.7 7.9 13.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SLT_L PF14718.6 CDO68889.1 - 0.042 14.0 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain NTF2 PF02136.20 CDO68890.1 - 1.1e-28 100.2 0.0 2.2e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Lysine_decarbox PF03641.14 CDO68890.1 - 2.7e-22 79.3 0.0 5.2e-22 78.3 0.0 1.5 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CDO68890.1 - 1.4e-06 28.0 1.3 4.4e-06 26.4 1.9 1.6 2 0 0 2 2 2 1 SLOG cluster4 family Sterol-sensing PF12349.8 CDO68892.1 - 1.5e-34 119.0 9.4 1.5e-34 119.0 9.4 2.3 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CDO68892.1 - 7e-15 54.2 1.7 1.1e-14 53.6 1.7 1.1 1 0 0 1 1 1 1 Patched family Biotin_lipoyl PF00364.22 CDO68893.1 - 7.4e-20 70.6 0.2 1.4e-19 69.7 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CDO68893.1 - 2.3e-07 31.0 0.0 6.4e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain PID PF00640.23 CDO68893.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) CCDC53 PF10152.9 CDO68893.1 - 3.4 8.1 6.6 0.31 11.5 1.0 2.0 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Rad1 PF02144.16 CDO68894.1 - 1.1e-73 247.7 0.0 1.3e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hat1_N PF10394.9 CDO68895.1 - 8.9e-58 195.1 1.8 9.3e-58 195.0 0.3 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 CDO68895.1 - 0.00097 19.4 0.0 0.0027 17.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 CDO68895.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family F-box-like PF12937.7 CDO68896.1 - 1.7e-06 27.8 0.5 6.7e-06 25.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like Acetyltransf_1 PF00583.25 CDO68898.1 - 0.0051 17.0 0.0 0.029 14.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO68898.1 - 0.032 14.6 0.0 2.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDO68898.1 - 0.11 12.4 0.0 6.6 6.7 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain MIF PF01187.18 CDO68899.1 - 8.2e-18 64.8 0.0 9e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Amidohydro_1 PF01979.20 CDO68900.1 - 5.6e-12 45.6 0.0 3.8e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CDO68900.1 - 8.9e-11 41.9 0.3 0.00035 20.2 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.12 CDO68900.1 - 0.0014 18.5 0.9 15 5.7 0.1 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat zf-MYND PF01753.18 CDO68901.1 - 9.4e-10 38.4 14.8 2.1e-09 37.3 14.8 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 CDO68901.1 - 0.011 15.8 7.6 0.027 14.5 7.6 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Pyr_redox_2 PF07992.14 CDO68905.1 - 2.7e-44 151.6 1.2 5.1e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDO68905.1 - 7.2e-29 100.3 0.4 1.2e-27 96.3 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain FAD_oxidored PF12831.7 CDO68905.1 - 5.5e-08 32.6 0.2 7.4e-08 32.2 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CDO68905.1 - 8e-06 24.8 4.7 0.015 14.0 1.6 2.7 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 CDO68905.1 - 0.0005 19.4 2.0 0.31 10.3 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDO68905.1 - 0.0019 17.3 4.2 0.0044 16.2 4.2 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CDO68905.1 - 0.0066 16.6 1.2 0.018 15.3 1.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CDO68905.1 - 0.016 14.3 0.0 0.053 12.6 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 CDO68905.1 - 0.034 13.4 0.5 0.07 12.4 0.5 1.4 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 CDO68905.1 - 0.036 13.2 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 CDO68905.1 - 0.21 12.2 4.0 7.1 7.3 1.2 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO68905.1 - 0.85 9.6 5.1 6.5 6.7 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CDO68905.1 - 3.3 6.7 9.9 0.29 10.2 4.0 2.1 3 0 0 3 3 3 0 FAD binding domain DUF2514 PF10721.9 CDO68906.1 - 0.064 13.3 6.7 0.22 11.5 6.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Histone_HNS PF00816.21 CDO68906.1 - 3.4 8.5 12.8 0.27 12.1 2.4 2.7 3 0 0 3 3 3 0 H-NS histone family Rpp20 PF12328.8 CDO68909.1 - 4.7e-08 33.1 0.0 6.3e-07 29.4 0.0 2.4 2 1 1 3 3 3 1 Rpp20 subunit of nuclear RNase MRP and P Prok-E2_B PF14461.6 CDO68909.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B eRF1_2 PF03464.15 CDO68910.1 - 6.6e-48 162.4 0.1 1.4e-47 161.3 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CDO68910.1 - 2e-39 134.6 0.3 4e-39 133.6 0.3 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CDO68910.1 - 1.9e-20 73.2 0.0 3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CDO68910.1 - 7.7e-11 42.4 0.1 1.3e-10 41.7 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CDO68910.1 - 3.6e-09 37.0 0.1 6.4e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Ribonuclease_3 PF00636.26 CDO68911.1 - 9.3e-38 129.1 0.0 3.3e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CDO68911.1 - 3.3e-22 79.0 0.1 4.3e-13 49.5 0.0 3.5 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 CDO68911.1 - 1.7e-16 60.1 0.0 3.9e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 CDO68911.1 - 1.9e-14 53.8 0.0 3.5e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDO68911.1 - 1.2e-13 51.5 0.0 2.4e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDO68911.1 - 1.3e-06 28.7 0.0 3.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 CDO68911.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Phosducin PF02114.16 CDO68912.1 - 5.1e-08 32.2 0.0 9.2e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Phosducin PNP_phzG_C PF10590.9 CDO68912.1 - 0.13 12.4 1.8 0.32 11.1 1.8 1.7 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region DUF3140 PF11338.8 CDO68912.1 - 1.1 9.7 3.3 56 4.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3140) Ras PF00071.22 CDO68913.1 - 7.1e-49 165.5 0.2 9e-49 165.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO68913.1 - 4.2e-22 78.6 0.1 7e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO68913.1 - 9.8e-08 31.6 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDO68913.1 - 0.0017 17.9 0.1 0.0026 17.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain rhaM PF05336.13 CDO68914.1 - 3.6e-32 110.6 0.1 4.1e-32 110.5 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Ras PF00071.22 CDO68915.1 - 8.3e-37 126.3 0.0 9.8e-37 126.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO68915.1 - 8.1e-10 39.0 0.0 1.2e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Rnk_N PF14760.6 CDO68915.1 - 0.026 15.0 0.9 0.25 11.8 0.1 2.4 2 0 0 2 2 2 0 Rnk N-terminus PET117 PF15786.5 CDO68915.1 - 0.04 14.2 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial DUF1077 PF06417.12 CDO68916.1 - 1e-46 157.7 0.1 1.3e-46 157.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Senescence PF06911.12 CDO68917.1 - 6.7e-41 140.6 6.3 2.5e-40 138.8 6.3 2.0 1 1 0 1 1 1 1 Senescence-associated protein MA3 PF02847.17 CDO68917.1 - 1.4e-28 99.2 0.4 2.4e-28 98.4 0.4 1.4 1 0 0 1 1 1 1 MA3 domain MFMR_assoc PF16596.5 CDO68917.1 - 0.079 13.4 11.7 0.08 13.4 6.0 2.5 2 0 0 2 2 2 0 Disordered region downstream of MFMR DUF4636 PF15468.6 CDO68917.1 - 7.3 6.2 13.1 17 5.0 13.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) BLACT_WH PF17778.1 CDO68918.1 - 4.7e-16 58.5 0.4 7.9e-16 57.8 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain VCBS PF13517.6 CDO68919.1 - 1.2e-20 73.8 16.4 5.8e-09 36.4 0.6 5.4 3 2 2 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CDO68919.1 - 3.7e-08 33.3 14.5 0.013 15.7 0.0 6.1 6 0 0 6 6 6 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 CDO68919.1 - 0.0017 17.7 3.8 1.1 8.6 0.0 5.0 5 1 1 6 6 6 1 Insecticide toxin TcdB middle/N-terminal region Dockerin_1 PF00404.18 CDO68919.1 - 0.003 17.7 3.5 35 4.7 0.0 5.1 5 1 0 5 5 5 1 Dockerin type I domain GTP1_OBG PF01018.22 CDO68919.1 - 0.051 13.2 0.1 0.081 12.5 0.1 1.2 1 0 0 1 1 1 0 GTP1/OBG CRF-BP PF05428.11 CDO68922.1 - 0.2 10.4 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Cellulase PF00150.18 CDO68923.1 - 1.9e-12 47.2 0.3 2.4e-12 46.9 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 CDO68925.1 - 7.1e-37 125.1 0.0 4.6e-20 71.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDO68925.1 - 0.015 14.9 0.0 2.6 7.6 0.0 2.2 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CDO68925.1 - 0.016 14.9 0.2 0.61 9.8 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_7 PF16367.5 CDO68925.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif Peptidase_M50B PF13398.6 CDO68927.1 - 2.2e-37 128.6 17.7 3.1e-37 128.2 17.2 1.5 1 1 0 1 1 1 1 Peptidase M50B-like ABC_tran PF00005.27 CDO68928.1 - 2.3e-43 148.0 0.1 1.4e-20 74.2 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CDO68928.1 - 1.2e-18 68.0 0.7 2.9e-07 30.6 0.3 4.7 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDO68928.1 - 5.4e-14 52.1 1.0 0.00057 19.4 0.1 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDO68928.1 - 1.2e-07 31.4 0.1 0.015 15.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CDO68928.1 - 2.1e-06 28.0 0.0 0.2 12.0 0.0 3.8 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 CDO68928.1 - 5.3e-06 26.7 0.1 0.0036 17.4 0.0 3.3 3 1 1 4 4 2 1 Helicase HerA, central domain AAA_16 PF13191.6 CDO68928.1 - 1.6e-05 25.3 1.3 0.014 15.7 0.0 3.7 5 0 0 5 5 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 CDO68928.1 - 2.1e-05 24.6 0.0 0.12 12.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CDO68928.1 - 2.4e-05 24.9 0.1 0.021 15.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 CDO68928.1 - 2.4e-05 24.9 9.9 0.012 16.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain HEAT_2 PF13646.6 CDO68928.1 - 5.5e-05 23.5 16.1 0.019 15.4 0.3 4.4 4 1 1 5 5 3 2 HEAT repeats Chromo PF00385.24 CDO68928.1 - 8e-05 22.5 0.2 0.00018 21.3 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RsgA_GTPase PF03193.16 CDO68928.1 - 0.0001 22.3 0.0 0.23 11.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 CDO68928.1 - 0.00014 21.7 0.2 0.48 10.1 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 CDO68928.1 - 0.00015 22.1 0.0 0.36 11.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 CDO68928.1 - 0.00018 21.9 0.0 3.3 8.2 0.0 4.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDO68928.1 - 0.00025 21.4 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CDO68928.1 - 0.00041 20.3 0.1 5.2 6.9 0.0 3.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CDO68928.1 - 0.00048 20.1 0.1 0.5 10.3 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 CDO68928.1 - 0.00071 19.8 0.0 1.3 9.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain HEAT PF02985.22 CDO68928.1 - 0.00082 19.4 8.3 0.11 12.8 0.0 5.1 5 0 0 5 5 4 1 HEAT repeat MeaB PF03308.16 CDO68928.1 - 0.00086 18.4 0.2 0.31 10.0 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 CDO68928.1 - 0.0025 18.0 0.1 0.86 9.9 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CDO68928.1 - 0.0035 17.1 0.2 3.4 7.3 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 CDO68928.1 - 0.0042 16.6 0.1 2.8 7.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region 4HB PF17947.1 CDO68928.1 - 0.0077 16.3 2.2 0.019 15.0 0.0 2.8 3 0 0 3 3 2 1 Four helical bundle domain AAA_13 PF13166.6 CDO68928.1 - 0.014 14.1 0.0 1.4 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CDO68928.1 - 0.02 14.1 0.0 2.5 7.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 CDO68928.1 - 0.021 14.0 0.1 3.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) HEAT_EZ PF13513.6 CDO68928.1 - 0.028 14.9 10.2 8.4 7.0 1.0 5.7 5 1 1 6 6 5 0 HEAT-like repeat AAA_24 PF13479.6 CDO68928.1 - 0.028 14.1 2.2 2.5 7.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CDO68928.1 - 0.041 13.8 0.1 5.6 6.9 0.0 2.7 2 0 0 2 2 2 0 NTPase Roc PF08477.13 CDO68928.1 - 0.058 13.6 0.0 19 5.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 CDO68928.1 - 0.072 12.4 0.0 2.7 7.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family U3snoRNP10 PF12397.8 CDO68928.1 - 0.072 13.4 0.8 0.21 12.0 0.8 1.9 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 TsaE PF02367.17 CDO68928.1 - 0.11 12.5 1.7 16 5.5 0.1 3.0 3 1 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CDO68928.1 - 0.12 12.4 0.0 8.6 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDO68928.1 - 0.19 11.8 5.1 18 5.3 0.1 4.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) CLP1_P PF16575.5 CDO68928.1 - 0.24 11.2 2.2 19 4.9 0.0 3.0 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop V_ATPase_I PF01496.19 CDO68929.1 - 0 1062.6 0.0 0 1062.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.12 CDO68929.1 - 0.024 15.2 2.0 0.079 13.6 0.7 2.5 3 0 0 3 3 3 0 SlyX adh_short_C2 PF13561.6 CDO68929.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Topo-VIb_trans PF09239.11 CDO68930.1 - 0.013 15.3 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer DUF1631 PF07793.11 CDO68933.1 - 8.8 4.6 10.0 12 4.2 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DDE_Tnp_4 PF13359.6 CDO68934.1 - 2.6e-10 40.2 0.0 3.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 CDO68935.1 - 5.6e-30 104.3 0.0 8.6e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_dimeris PF09026.10 CDO68935.1 - 0.034 14.5 1.0 0.066 13.6 1.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2786 PF10979.8 CDO68935.1 - 0.096 12.6 1.2 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) HTH_Tnp_Tc5 PF03221.16 CDO68936.1 - 1.7e-10 40.8 0.0 5.7e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain JmjC PF02373.22 CDO68938.1 - 6.7e-39 132.9 0.0 1.3e-38 131.9 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CDO68938.1 - 3.7e-15 55.6 0.6 8.9e-15 54.4 0.6 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 CDO68938.1 - 1.1e-12 48.1 0.3 3.1e-12 46.6 0.3 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDO68938.1 - 8.8e-12 45.2 0.6 2.8e-11 43.6 0.6 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 CDO68938.1 - 0.0073 16.2 2.5 0.02 14.8 2.5 1.8 1 0 0 1 1 1 1 PHD-finger NIBRIN_BRCT_II PF16508.5 CDO68939.1 - 0.0048 17.2 0.0 0.0099 16.2 0.0 1.5 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein CAP59_mtransfer PF11735.8 CDO68940.1 - 3.3e-36 125.2 0.0 6.9e-36 124.1 0.0 1.5 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 Nup84_Nup100 PF04121.13 CDO68941.1 - 3.1e-164 547.9 0.0 3.7e-164 547.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Nic96 PF04097.14 CDO68941.1 - 0.02 13.4 1.1 0.02 13.4 0.1 1.4 2 0 0 2 2 2 0 Nup93/Nic96 tRNA-synt_1 PF00133.22 CDO68942.1 - 9.9e-210 697.8 0.0 1.8e-208 693.6 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDO68942.1 - 2.1e-31 109.0 0.3 4.7e-31 107.8 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDO68942.1 - 4.1e-16 58.7 0.0 5.8e-09 35.2 0.0 4.0 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CDO68942.1 - 1.1e-11 44.6 0.1 2e-07 30.7 0.1 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 CDO68942.1 - 0.0058 16.9 0.8 0.0058 16.9 0.8 3.8 4 0 0 4 4 4 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 CDO68942.1 - 0.0093 15.3 0.0 0.3 10.4 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 CDO68942.1 - 0.061 12.6 0.1 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 CDO68942.1 - 0.11 11.3 0.0 0.3 10.0 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (K) RVT_2 PF07727.14 CDO68943.1 - 3e-18 66.3 0.0 1.1e-14 54.7 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3799 PF12684.7 CDO68943.1 - 0.07 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) rve PF00665.26 CDO68944.1 - 3e-21 75.8 0.0 1.6e-20 73.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain DDE_1 PF03184.19 CDO68944.1 - 8.7e-18 64.6 0.0 1.5e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotran_gag_2 PF14223.6 CDO68944.1 - 4.8e-11 42.5 0.1 3.7e-10 39.6 0.0 2.3 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO68944.1 - 4.7e-09 36.0 0.7 1.6e-08 34.3 0.1 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO68944.1 - 0.00018 21.2 1.0 0.00083 19.1 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain DDE_3 PF13358.6 CDO68944.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease BRO1 PF03097.18 CDO68946.1 - 2.3e-96 323.0 0.0 5.4e-96 321.8 0.0 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CDO68946.1 - 9.2e-57 192.6 8.1 2.4e-56 191.2 8.1 1.8 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF3421 PF11901.8 CDO68947.1 - 2e-32 111.5 0.0 2.9e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) IMUP PF15761.5 CDO68947.1 - 0.39 11.4 9.8 0.68 10.7 9.8 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CDO68947.1 - 3.6 7.1 16.2 4.7 6.7 16.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WLM PF08325.10 CDO68948.1 - 3.7e-12 46.7 15.2 1.5e-05 25.2 8.7 4.0 2 1 1 3 3 3 2 WLM domain DUF45 PF01863.17 CDO68948.1 - 0.00041 20.5 0.3 0.00085 19.4 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 2_5_RNA_ligase2 PF13563.6 CDO68948.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily PFK PF00365.20 CDO68949.1 - 3.3e-157 522.1 0.1 4.1e-80 269.2 0.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase DUF1932 PF09130.11 CDO68949.1 - 0.024 14.6 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) PapJ PF14855.6 CDO68949.1 - 0.093 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone KilA-N PF04383.13 CDO68950.1 - 0.05 13.5 1.7 0.59 10.0 0.0 2.6 2 1 0 2 2 2 0 KilA-N domain DUF4407 PF14362.6 CDO68950.1 - 0.92 8.8 7.1 1.7 8.0 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SKA1 PF07160.12 CDO68950.1 - 4.5 7.0 9.8 8.1 6.2 9.8 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 MAD PF05557.13 CDO68952.1 - 0.00086 17.8 38.3 0.0014 17.1 38.3 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein EzrA PF06160.12 CDO68952.1 - 0.0017 16.6 16.8 0.0017 16.6 16.8 2.5 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA TMF_DNA_bd PF12329.8 CDO68952.1 - 0.0099 15.9 9.8 0.0099 15.9 9.8 5.3 4 1 2 6 6 6 2 TATA element modulatory factor 1 DNA binding LMBR1 PF04791.16 CDO68952.1 - 1.5 7.7 16.1 2.5 6.9 16.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SpecificRecomb PF10136.9 CDO68952.1 - 1.5 7.1 19.0 2.2 6.5 19.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase Fez1 PF06818.15 CDO68952.1 - 1.9 8.9 40.5 0.38 11.2 19.8 2.8 1 1 1 2 2 2 0 Fez1 Baculo_PEP_C PF04513.12 CDO68952.1 - 2.8 8.0 14.7 1.2 9.1 1.0 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cob_adeno_trans PF01923.18 CDO68952.1 - 5.6 7.1 16.1 3.4 7.8 10.6 2.9 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Lebercilin PF15619.6 CDO68952.1 - 8.4 6.0 43.5 14 5.3 36.0 2.9 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease FliD_N PF02465.18 CDO68952.1 - 9.8 7.0 16.9 33 5.3 0.1 3.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Proteasome PF00227.26 CDO68953.1 - 2.2e-53 180.6 0.1 3.8e-53 179.8 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDO68953.1 - 1.4e-13 50.2 0.1 3e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CHZ PF09649.10 CDO68954.1 - 2.9e-11 42.6 1.4 2.9e-11 42.6 1.4 3.3 2 1 1 3 3 3 1 Histone chaperone domain CHZ DNA_pol_phi PF04931.13 CDO68954.1 - 0.094 10.8 26.0 0.11 10.6 26.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi VID27_N PF17748.1 CDO68954.1 - 0.58 10.0 11.4 0.73 9.7 11.4 1.2 1 0 0 1 1 1 0 VID27 N-terminal region Nop14 PF04147.12 CDO68954.1 - 0.7 8.0 17.0 0.78 7.9 17.0 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 CDO68954.1 - 2.1 6.4 6.0 1.9 6.5 6.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 CDO68954.1 - 2.4 7.4 17.2 2.6 7.3 17.2 1.0 1 0 0 1 1 1 0 BUD22 Cytomega_UL84 PF06284.11 CDO68954.1 - 5 5.5 6.3 4.4 5.7 6.3 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein PI3K_1B_p101 PF10486.9 CDO68954.1 - 5 4.8 7.4 5.1 4.8 7.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM176 PF14851.6 CDO68954.1 - 7.5 6.2 17.4 0.14 11.8 9.5 1.9 1 1 1 2 2 2 0 FAM176 family 3-PAP PF12578.8 CDO68955.1 - 3.2 7.5 4.7 1.6 8.5 0.2 2.5 2 1 0 2 2 2 0 Myotubularin-associated protein AAA_18 PF13238.6 CDO68956.1 - 8.3e-09 36.1 0.0 4.3e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDO68956.1 - 2.5e-08 34.2 0.0 0.00017 21.7 0.0 2.8 2 1 1 3 3 3 2 AAA domain SKI PF01202.22 CDO68956.1 - 1.4e-05 25.2 0.0 0.00041 20.5 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_16 PF13191.6 CDO68956.1 - 0.0001 22.8 0.0 0.00018 21.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 CDO68956.1 - 0.00059 19.6 0.0 0.00097 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CDO68956.1 - 0.0015 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CDO68956.1 - 0.0017 18.7 0.0 0.0054 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 CDO68956.1 - 0.0031 17.3 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 CDO68956.1 - 0.0033 17.7 0.0 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 CDO68956.1 - 0.0037 17.1 0.0 0.41 10.5 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase APS_kinase PF01583.20 CDO68956.1 - 0.0094 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.6 CDO68956.1 - 0.01 16.2 0.0 0.028 14.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDO68956.1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 CDO68956.1 - 0.039 13.2 0.0 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 CDO68956.1 - 0.049 13.4 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Thymidylate_kin PF02223.17 CDO68956.1 - 0.052 13.2 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA PF00004.29 CDO68956.1 - 0.059 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PEPCK_ATP PF01293.20 CDO68956.1 - 0.092 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase TsaE PF02367.17 CDO68956.1 - 0.12 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 CDO68956.1 - 0.21 10.7 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain bZIP_2 PF07716.15 CDO68957.1 - 1.1e-10 41.4 9.2 1.1e-10 41.4 9.2 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CDO68957.1 - 1.9e-10 40.7 13.0 2.3e-10 40.4 6.4 2.3 2 0 0 2 2 2 1 bZIP transcription factor Fmp27_WPPW PF10359.9 CDO68957.1 - 0.082 11.8 0.0 0.099 11.5 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TSC22 PF01166.18 CDO68957.1 - 0.11 12.8 1.0 0.25 11.7 0.1 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF724 PF05266.14 CDO68957.1 - 0.13 12.0 4.3 0.2 11.5 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DDE_Tnp_4 PF13359.6 CDO68957.1 - 0.24 11.1 0.1 0.4 10.3 0.1 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease bZIP_Maf PF03131.17 CDO68957.1 - 0.48 11.0 14.6 0.19 12.3 10.9 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF5384 PF17358.2 CDO68957.1 - 9.7 6.2 15.8 0.38 10.8 7.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5384) AAA_lid_2 PF17863.1 CDO68959.1 - 0.022 14.6 0.1 0.022 14.6 0.1 2.1 2 0 0 2 2 2 0 AAA lid domain Rax2 PF12768.7 CDO68960.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 CDO68960.1 - 0.63 9.5 2.8 1.4 8.4 2.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain BRO1 PF03097.18 CDO68961.1 - 1.1e-20 73.9 0.0 1.4e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain RIBIOP_C PF04950.12 CDO68962.1 - 9.6e-120 399.4 0.0 1.4e-119 398.8 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CDO68962.1 - 6e-18 64.7 0.0 4.5e-17 61.9 0.0 2.4 1 1 0 1 1 1 1 AARP2CN (NUC121) domain EF-hand_8 PF13833.6 CDO68962.1 - 0.064 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Vps53_N PF04100.12 CDO68963.1 - 1.3e-91 307.5 0.3 2e-91 306.8 0.3 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 CDO68963.1 - 1.2e-06 28.0 3.7 3.2e-06 26.6 3.7 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex VPS53_C PF16854.5 CDO68963.1 - 3.7e-05 23.7 0.0 3.7e-05 23.7 0.0 3.4 4 1 1 5 5 5 1 Vacuolar protein sorting-associated protein 53 C-terminus DUF2451 PF10474.9 CDO68963.1 - 0.00049 19.9 0.8 0.005 16.7 0.1 2.8 2 1 1 3 3 3 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 CDO68963.1 - 0.0019 17.2 0.1 0.0019 17.2 0.1 3.2 4 0 0 4 4 4 1 RINT-1 / TIP-1 family DUF1664 PF07889.12 CDO68963.1 - 0.012 15.6 3.2 0.012 15.6 3.2 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 CDO68963.1 - 0.07 13.4 5.2 0.32 11.3 0.0 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Sec5 PF15469.6 CDO68963.1 - 0.23 11.3 4.7 0.58 9.9 3.8 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec5 Occludin_ELL PF07303.13 CDO68963.1 - 0.42 11.3 2.9 3 8.6 0.2 3.0 1 1 1 2 2 2 0 Occludin homology domain RRP36 PF06102.12 CDO68963.1 - 0.74 9.8 7.6 0.13 12.3 3.1 2.0 2 1 0 2 2 2 0 rRNA biogenesis protein RRP36 DUF885 PF05960.11 CDO68963.1 - 8.2 5.9 7.8 1.8 8.1 2.5 2.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF885) GIT_CC PF16559.5 CDO68963.1 - 8.5 6.3 10.1 2.8 7.9 0.1 3.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Autophagy_N PF03986.13 CDO68964.1 - 1.1e-41 141.9 1.7 2.1e-41 141.1 0.0 2.4 3 0 0 3 3 3 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CDO68964.1 - 1.1e-17 64.3 0.1 2.5e-17 63.2 0.1 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CDO68964.1 - 4.6e-12 45.2 1.8 9.1e-12 44.3 1.8 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-LYAR PF08790.11 CDO68965.1 - 3e-13 49.4 2.3 6.6e-13 48.3 2.3 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 CDO68965.1 - 0.029 14.0 0.7 2.7 7.6 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 CDO68965.1 - 0.16 12.1 0.4 0.31 11.2 0.4 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain Nkap_C PF06047.11 CDO68966.1 - 3.3e-42 142.7 5.2 3.3e-42 142.7 5.2 3.5 4 1 0 4 4 4 1 NF-kappa-B-activating protein C-terminal domain OsmC PF02566.19 CDO68967.1 - 1.4e-13 51.1 0.0 2.1e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Retrotrans_gag PF03732.17 CDO68969.1 - 3.5e-09 36.8 0.3 5.6e-09 36.1 0.3 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Ndc1_Nup PF09531.10 CDO68971.1 - 2.9e-85 287.2 12.3 3.8e-85 286.8 12.3 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Redoxin PF08534.10 CDO68973.1 - 5.7e-33 113.7 0.0 6.5e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CDO68973.1 - 1.4e-07 31.5 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDO68974.1 - 1.7e-35 121.9 0.0 2.2e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CDO68974.1 - 1.6e-11 44.2 0.0 2.3e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Pex19 PF04614.12 CDO68975.1 - 6e-64 216.2 0.6 6e-64 216.2 0.6 2.0 2 0 0 2 2 2 1 Pex19 protein family DUF937 PF06078.11 CDO68975.1 - 0.23 12.0 2.9 14 6.3 2.9 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF937) MAGI_u5 PF16666.5 CDO68975.1 - 1.2 9.3 7.8 2.5 8.2 7.8 1.5 1 0 0 1 1 1 0 Unstructured region on MAGI Solute_trans_a PF03619.16 CDO68976.1 - 3.9e-97 324.9 10.4 4.6e-97 324.7 10.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Porphobil_deam PF01379.20 CDO68976.1 - 0.25 10.8 0.0 0.39 10.2 0.0 1.2 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain APH PF01636.23 CDO68977.1 - 3.2e-09 37.1 0.1 4.4e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HMG_box PF00505.19 CDO68979.1 - 6.5e-14 52.1 13.3 2.2e-10 40.8 0.2 4.3 3 2 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO68979.1 - 1.1e-13 51.5 7.8 1.2e-10 41.8 0.2 3.9 3 2 0 3 3 3 2 HMG-box domain ApoO PF09769.9 CDO68979.1 - 0.0061 16.5 2.1 0.41 10.6 0.0 2.6 2 0 0 2 2 2 1 Apolipoprotein O DUF4407 PF14362.6 CDO68979.1 - 0.0069 15.8 12.7 0.0069 15.8 12.7 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4407) Arg_decarbox_C PF17944.1 CDO68979.1 - 0.27 11.8 3.7 12 6.6 0.1 3.1 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension DUF1289 PF06945.13 CDO68979.1 - 0.82 9.5 3.6 15 5.5 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) RGS PF00615.19 CDO68980.1 - 6.8e-09 36.0 2.0 0.00067 19.9 0.3 3.0 2 1 0 2 2 2 2 Regulator of G protein signaling domain L51_S25_CI-B8 PF05047.16 CDO68981.1 - 2.5e-15 56.1 0.0 3.4e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_2 PF00891.18 CDO68981.1 - 0.061 12.6 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain adh_short PF00106.25 CDO68982.1 - 6.7e-31 107.3 0.0 7.7e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO68982.1 - 2e-19 70.1 0.0 2.4e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CDO68982.1 - 2.4e-06 27.2 0.0 2.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CDO68982.1 - 3.6e-06 27.0 0.1 5.7e-06 26.4 0.1 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDO68982.1 - 4e-05 23.6 0.2 5e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 NAD(P)H-binding EPSP_synthase PF00275.20 CDO68983.1 - 3.8e-121 404.7 0.0 5.8e-121 404.1 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CDO68983.1 - 2.1e-102 341.8 0.1 9.6e-102 339.6 0.0 2.1 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CDO68983.1 - 3.4e-56 191.0 0.0 6.6e-56 190.1 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CDO68983.1 - 3.9e-33 114.8 0.0 2.6e-32 112.2 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 CDO68983.1 - 8.8e-27 93.2 0.0 3e-26 91.5 0.0 2.0 2 0 0 2 2 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 CDO68983.1 - 3.2e-09 36.9 0.1 1.2e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 CDO68983.1 - 2.1e-06 27.4 0.4 7.2e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 CDO68983.1 - 3.5e-06 27.1 0.0 9.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 CDO68983.1 - 0.014 15.6 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDO68983.1 - 0.047 14.0 0.0 0.22 11.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDO68983.1 - 0.12 12.8 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_8 PF12780.7 CDO68983.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 6PF2K PF01591.18 CDO68983.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase zf-C2H2 PF00096.26 CDO68985.1 - 2e-08 34.2 17.0 8.5e-06 26.0 1.3 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO68985.1 - 1.8e-05 25.2 14.5 0.012 16.4 0.6 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDO68985.1 - 3.5e-05 24.0 16.0 0.0076 16.6 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDO68985.1 - 0.013 15.4 2.7 1.3 9.1 0.1 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 CDO68985.1 - 0.035 14.4 1.2 0.035 14.4 1.2 2.3 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 CDO68985.1 - 0.098 12.5 9.4 1.3 8.9 0.1 4.1 3 1 1 4 4 4 0 GAGA factor Zn-C2H2_12 PF18112.1 CDO68985.1 - 0.2 12.1 0.8 1.6 9.2 0.2 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain FOXP-CC PF16159.5 CDO68985.1 - 1 10.1 3.4 11 6.7 0.2 2.9 3 1 0 3 3 3 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 CDO68985.1 - 1.4 8.8 7.5 11 5.9 1.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Rrn6 PF10214.9 CDO68985.1 - 2.2 6.7 6.5 2.7 6.4 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Got1 PF04178.12 CDO68986.1 - 5.5e-19 68.7 9.4 6.9e-19 68.3 9.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Pkinase PF00069.25 CDO68987.1 - 4.4e-56 190.2 0.0 5.4e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO68987.1 - 6.8e-38 130.4 0.0 9.1e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO68987.1 - 5.3e-07 29.2 0.0 8.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDO68987.1 - 0.0065 15.3 0.0 0.0095 14.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO68987.1 - 0.012 15.6 0.2 0.41 10.5 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO68987.1 - 0.037 13.0 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain BAG PF02179.16 CDO68988.1 - 2.9e-22 78.9 0.0 6.9e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 CDO68988.1 - 7.5e-09 35.2 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 CDO68988.1 - 0.11 12.6 0.0 0.4 10.7 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain DUF5527 PF17665.1 CDO68989.1 - 0.061 12.9 1.8 0.075 12.6 1.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Retrotran_gag_2 PF14223.6 CDO68990.1 - 1.9e-09 37.3 0.0 2.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVT_1 PF00078.27 CDO68991.1 - 7.4e-15 55.1 0.0 1.5e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDO68991.1 - 9.3e-13 48.1 0.0 2.3e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO68991.1 - 0.04 14.2 0.1 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 CDO68992.1 - 6.4e-06 26.4 1.9 1.2e-05 25.5 0.2 2.4 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 CDO68992.1 - 0.00028 21.5 0.0 0.00077 20.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDO68992.1 - 0.016 14.9 0.3 0.038 13.8 0.2 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 CDO68992.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4939 PF16297.5 CDO68992.1 - 0.073 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) gag-asp_proteas PF13975.6 CDO68992.1 - 0.11 13.1 0.0 0.32 11.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 CDO68992.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Ty3 transposon peptidase MAP65_ASE1 PF03999.12 CDO68992.1 - 3.3 6.3 10.9 4.9 5.7 10.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) NPR3 PF03666.13 CDO68992.1 - 4.6 5.9 8.4 8.6 5.0 8.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 CDO68992.1 - 7 4.6 7.2 9.8 4.2 7.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apt1 PF10351.9 CDO68992.1 - 9.9 4.9 10.3 15 4.2 10.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain CBF PF03914.17 CDO68995.1 - 5.7e-30 104.6 1.3 5.7e-30 104.6 1.3 2.6 3 1 0 3 3 3 1 CBF/Mak21 family Myb_Cef PF11831.8 CDO68996.1 - 3.5e-63 213.4 0.1 3.5e-63 213.4 0.1 3.6 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 CDO68996.1 - 3.2e-22 78.4 6.0 9.5e-11 41.7 1.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDO68996.1 - 2e-19 69.6 6.9 1.3e-12 47.8 3.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain RTX PF02382.15 CDO68996.1 - 0.0029 17.4 1.2 0.0049 16.6 1.2 1.3 1 0 0 1 1 1 1 N-terminal domain in RTX protein DUF3499 PF12005.8 CDO68996.1 - 0.57 10.8 3.9 0.65 10.6 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) TPR_21 PF09976.9 CDO68997.1 - 0.071 12.8 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF1690 PF07956.11 CDO68998.1 - 4.3e-37 127.6 3.6 5.5e-37 127.3 3.6 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF3220 PF11516.8 CDO68998.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Metal_resist PF13801.6 CDO68998.1 - 0.035 14.3 4.9 2.3 8.4 1.8 2.2 2 0 0 2 2 2 0 Heavy-metal resistance Histone_HNS PF00816.21 CDO68998.1 - 1.4 9.8 5.0 24 5.8 0.2 2.4 2 0 0 2 2 2 0 H-NS histone family APG6_N PF17675.1 CDO68998.1 - 2.8 8.5 12.5 9.9 6.7 11.5 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region HA2 PF04408.23 CDO68999.1 - 8.5e-17 61.4 0.0 1.9e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDO68999.1 - 2.7e-11 43.8 0.0 5.8e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDO68999.1 - 2.3e-09 37.5 0.0 6e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CDO68999.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF572 PF04502.13 CDO69000.1 - 3.3e-81 273.5 6.3 3.7e-81 273.3 6.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 CDO69000.1 - 0.018 15.0 0.8 0.69 9.9 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif UQ_con PF00179.26 CDO69002.1 - 1.1e-44 151.5 0.0 1.3e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDO69002.1 - 0.00056 19.6 0.0 0.00068 19.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CDO69002.1 - 0.0011 19.2 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain DUF3684 PF12449.8 CDO69003.1 - 1e-74 252.1 0.0 1.2e-74 251.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) DUF3684 PF12449.8 CDO69004.1 - 4.2e-252 839.5 0.0 2.5e-251 836.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3684) TGT PF01702.18 CDO69005.1 - 1.3e-32 113.3 0.0 1.8e-22 80.0 0.0 2.2 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase DUF2156 PF09924.9 CDO69005.1 - 0.0085 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) EF-hand_4 PF12763.7 CDO69006.1 - 1.4e-38 131.1 0.0 3.3e-15 55.9 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CDO69006.1 - 1.5e-11 44.6 0.1 9.7e-05 22.8 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 CDO69006.1 - 8.4e-09 34.4 0.8 1.1 9.0 0.0 5.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 CDO69006.1 - 2.1e-06 27.2 0.4 5.6 7.2 0.0 5.3 5 0 0 5 5 5 1 EF-hand domain UBA PF00627.31 CDO69006.1 - 4e-06 26.6 0.0 8.6e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_8 PF13833.6 CDO69006.1 - 0.00022 21.0 0.0 5.8 6.8 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair Takusan PF04822.13 CDO69006.1 - 0.0079 16.1 0.8 0.034 14.0 0.8 2.1 1 0 0 1 1 1 1 Takusan TPR_MLP1_2 PF07926.12 CDO69006.1 - 0.03 14.4 45.3 0.13 12.3 14.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein UBA_4 PF14555.6 CDO69006.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Fez1 PF06818.15 CDO69006.1 - 0.12 12.8 35.1 0.035 14.6 19.3 2.3 1 1 1 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 CDO69006.1 - 1.3 9.0 37.6 0.21 11.6 11.2 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 CDO69006.1 - 1.3 8.6 35.8 2.4 7.7 35.8 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Bcr-Abl_Oligo PF09036.10 CDO69006.1 - 4.9 7.2 8.3 0.75 9.8 0.1 3.5 3 1 1 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain Spc7 PF08317.11 CDO69006.1 - 6.6 5.5 39.6 1.9 7.3 8.6 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 CDO69006.1 - 9.1 6.4 50.5 0.86 9.8 28.1 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) PDEase_II PF02112.15 CDO69007.1 - 1.2e-39 136.4 0.0 1.8e-38 132.5 0.0 2.5 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 CDO69007.1 - 3.9e-06 26.5 0.0 6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Packaging_FI PF14000.6 CDO69007.1 - 0.012 16.1 0.8 0.022 15.2 0.8 1.4 1 0 0 1 1 1 0 DNA packaging protein FI WD40 PF00400.32 CDO69008.1 - 1.6e-36 123.7 2.5 1.1e-06 29.3 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.12 CDO69008.1 - 1.1e-34 120.3 6.5 1.1e-34 120.3 6.5 3.8 3 2 0 3 3 3 1 Striatin family ANAPC4_WD40 PF12894.7 CDO69008.1 - 1.6e-11 44.3 0.6 0.15 12.3 0.0 5.5 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CDO69008.1 - 0.00043 19.1 0.0 0.013 14.3 0.0 2.8 2 1 1 3 3 3 1 Nup133 N terminal like EF-hand_4 PF12763.7 CDO69009.1 - 2.2e-41 140.0 0.0 2.1e-10 40.5 0.0 4.3 4 0 0 4 4 4 4 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CDO69009.1 - 6.3e-12 45.8 0.0 0.0012 19.3 0.3 4.9 4 2 1 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.32 CDO69009.1 - 2.6e-10 39.1 0.0 0.071 12.7 0.0 5.3 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 CDO69009.1 - 9e-07 28.3 1.3 1.6 8.8 0.0 5.8 6 0 0 6 6 6 2 EF-hand domain GAT PF03127.14 CDO69009.1 - 4.5e-06 26.9 2.6 5.3e-05 23.4 2.6 2.4 1 1 0 1 1 1 1 GAT domain End3 PF12761.7 CDO69009.1 - 2.9e-05 24.3 2.0 0.031 14.4 0.0 2.8 3 0 0 3 3 3 2 Actin cytoskeleton-regulatory complex protein END3 EF-hand_8 PF13833.6 CDO69009.1 - 0.00057 19.7 0.0 2.2 8.2 0.0 4.8 5 0 0 5 5 5 1 EF-hand domain pair R3H PF01424.22 CDO69010.1 - 1.4e-10 41.0 0.1 3.3e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 CDO69010.1 - 1.7e-07 30.9 0.0 3.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Endonuclease_NS PF01223.23 CDO69011.1 - 8.3e-55 186.1 0.0 1.1e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease MRP-L46 PF11788.8 CDO69012.1 - 2.5e-18 67.0 0.0 3.7e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 CDO69012.1 - 1.2e-09 38.3 0.1 2e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain V-ATPase_H_N PF03224.14 CDO69013.1 - 2.3e-63 214.4 0.2 7.9e-52 176.5 0.0 2.6 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 CDO69013.1 - 8.8e-43 145.1 0.1 4.2e-42 143.0 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 CDO69013.1 - 7.3e-07 29.0 0.3 0.77 9.9 0.0 5.0 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CDO69013.1 - 1.7e-06 27.8 0.1 0.031 14.5 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat Arm_2 PF04826.13 CDO69013.1 - 0.00012 21.7 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 Armadillo-like HEAT_2 PF13646.6 CDO69013.1 - 0.0036 17.6 0.0 0.14 12.6 0.0 3.1 2 2 1 3 3 3 1 HEAT repeats LemA PF04011.12 CDO69013.1 - 0.0037 17.1 0.1 0.0068 16.3 0.1 1.4 1 0 0 1 1 1 1 LemA family DUF2019 PF09450.10 CDO69013.1 - 0.011 15.6 0.0 0.091 12.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) Sec7_N PF12783.7 CDO69013.1 - 0.062 13.2 0.0 0.86 9.5 0.0 2.5 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RTP1_C1 PF10363.9 CDO69013.1 - 0.13 12.4 0.1 9.3 6.5 0.0 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 p450 PF00067.22 CDO69014.1 - 6.4e-36 124.1 0.0 8e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M9 PF01752.17 CDO69014.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Collagenase Tubulin PF00091.25 CDO69017.1 - 6e-70 235.4 0.0 1.1e-69 234.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDO69017.1 - 5.2e-47 159.1 0.6 1e-46 158.2 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CDO69017.1 - 0.001 19.3 0.0 0.0041 17.4 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CDO69017.1 - 0.0024 17.6 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CDO69017.1 - 0.099 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like HTH_3 PF01381.22 CDO69018.1 - 1.2e-12 47.7 0.2 1.8e-12 47.1 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 CDO69018.1 - 1e-10 41.9 1.5 3.5e-05 24.2 0.1 2.8 2 1 1 3 3 3 2 Multiprotein bridging factor 1 HTH_31 PF13560.6 CDO69018.1 - 6.8e-07 29.5 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CDO69018.1 - 0.00014 21.8 0.0 0.00034 20.6 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 CDO69018.1 - 0.022 14.6 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 CDO69018.1 - 0.068 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Peptidase_M17 PF00883.21 CDO69019.1 - 3.6e-105 351.7 0.0 5.3e-105 351.1 0.0 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 CDO69019.1 - 0.00038 20.3 0.7 0.00078 19.3 0.7 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Pdase_M17_N2 PF18295.1 CDO69019.1 - 0.084 13.1 1.1 0.17 12.1 1.1 1.5 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 NAD_binding_7 PF13241.6 CDO69020.1 - 4.2e-31 107.5 0.0 2.3e-30 105.1 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CDO69020.1 - 1.2e-22 79.3 1.0 1.9e-22 78.7 1.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 CDO69020.1 - 6.3e-14 51.1 0.5 1.2e-13 50.3 0.5 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.21 CDO69020.1 - 0.0012 18.3 0.1 0.016 14.6 0.0 2.4 2 1 0 2 2 2 1 ThiF family DUF4191 PF13829.6 CDO69021.1 - 0.06 12.7 5.7 0.38 10.1 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) AMO PF02461.16 CDO69021.1 - 0.076 12.8 5.8 0.09 12.5 5.8 1.1 1 0 0 1 1 1 0 Ammonia monooxygenase DUF4149 PF13664.6 CDO69021.1 - 0.75 10.2 6.7 6.8 7.1 3.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) RNA12 PF10443.9 CDO69022.1 - 8.4e-108 360.9 1.7 4e-53 180.7 1.4 2.6 1 1 1 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 CDO69022.1 - 1.6e-06 28.3 0.1 0.0018 18.2 0.0 2.5 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CDO69022.1 - 7.3e-05 23.2 1.4 0.00056 20.3 1.3 2.5 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 CDO69022.1 - 0.0017 18.0 0.0 0.0062 16.1 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CDO69022.1 - 0.0048 17.1 0.1 0.018 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDO69022.1 - 0.0076 16.5 0.7 0.047 14.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_6 PF12774.7 CDO69022.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 CDO69022.1 - 0.02 15.3 0.3 0.23 11.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NYD-SP28_assoc PF14775.6 CDO69022.1 - 0.21 11.7 1.3 0.81 9.8 0.1 2.6 3 0 0 3 3 3 0 Sperm tail C-terminal domain AAA_11 PF13086.6 CDO69022.1 - 0.33 10.7 6.2 0.29 10.9 2.9 2.3 2 1 0 2 2 2 0 AAA domain DUF974 PF06159.13 CDO69023.1 - 4.6e-79 265.7 0.0 6.2e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) p450 PF00067.22 CDO69024.1 - 1.2e-56 192.5 0.0 1.8e-56 191.8 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Bmt2 PF11968.8 CDO69025.1 - 4.1e-61 206.6 0.0 5.2e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 CDO69025.1 - 0.0087 15.9 0.0 0.032 14.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO69025.1 - 0.018 15.7 0.0 0.036 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDO69025.1 - 0.02 15.6 0.0 0.044 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FAD-oxidase_C PF02913.19 CDO69026.1 - 8.3e-55 186.1 0.1 1.2e-54 185.6 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDO69026.1 - 2.8e-21 75.7 0.6 8.8e-20 70.9 0.6 2.4 1 1 0 1 1 1 1 FAD binding domain Vta1_C PF18097.1 CDO69026.1 - 0.013 15.2 0.1 0.57 9.9 0.0 2.5 2 0 0 2 2 2 0 Vta1 C-terminal domain Ribosomal_L27A PF00828.19 CDO69027.1 - 1.1e-35 123.1 0.1 1.6e-35 122.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 5_nucleotid_C PF02872.18 CDO69028.1 - 2.8e-19 69.9 0.0 1.9e-15 57.4 0.0 2.5 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CDO69028.1 - 8.3e-09 36.2 0.4 1.2e-08 35.7 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Telomere_reg-2 PF10193.9 CDO69030.1 - 3.4e-29 101.5 0.0 1.1e-28 99.8 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein MFS_1 PF07690.16 CDO69031.1 - 1.5e-21 76.7 32.8 3.4e-21 75.6 23.7 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5392 PF17370.2 CDO69031.1 - 0.34 11.0 0.8 0.96 9.5 0.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5392) Vma12 PF11712.8 CDO69031.1 - 1.7 8.7 4.6 23 5.0 1.4 2.7 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sugar_tr PF00083.24 CDO69032.1 - 1.7e-78 264.5 6.8 2.3e-78 264.1 6.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO69032.1 - 2.7e-22 79.2 20.9 2.7e-22 79.2 20.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CDO69032.1 - 0.00037 19.1 10.7 0.00054 18.5 4.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) CDC50 PF03381.15 CDO69033.1 - 1.2e-94 317.0 0.0 1.9e-94 316.3 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family HOOK PF05622.12 CDO69034.1 - 5.2e-64 216.6 50.2 5.2e-64 216.6 50.2 3.0 1 1 1 2 2 2 2 HOOK protein Filament PF00038.21 CDO69034.1 - 0.00053 19.7 12.7 0.00053 19.7 12.7 5.2 1 1 3 4 4 4 1 Intermediate filament protein TPR_MLP1_2 PF07926.12 CDO69034.1 - 0.0095 16.0 92.7 0.034 14.2 12.5 8.4 5 3 2 7 7 7 5 TPR/MLP1/MLP2-like protein TSC22 PF01166.18 CDO69034.1 - 0.4 11.0 36.8 0.068 13.5 2.7 7.5 7 1 1 8 8 8 0 TSC-22/dip/bun family NYD-SP28_assoc PF14775.6 CDO69034.1 - 1.4 9.0 28.8 0.04 14.0 2.1 6.1 5 1 0 5 5 5 0 Sperm tail C-terminal domain Imm7 PF15585.6 CDO69034.1 - 2.2 8.6 10.7 0.096 13.0 0.4 3.5 3 1 0 3 3 3 0 Immunity protein 7 RTC PF01137.21 CDO69035.1 - 2.1e-81 272.4 0.0 2.4e-81 272.2 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CDO69035.1 - 6.6e-20 71.6 0.1 1.1e-19 70.8 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF4111 PF13427.6 CDO69035.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Alpha-amylase PF00128.24 CDO69036.1 - 7.6e-47 160.5 0.1 1.2e-46 159.8 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 CDO69036.1 - 4.4e-16 58.9 0.1 8e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) G-patch PF01585.23 CDO69037.1 - 8.1e-14 51.2 1.7 2.1e-13 49.9 1.7 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDO69037.1 - 2.7e-07 30.5 1.3 1.3e-06 28.4 1.3 2.2 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CDO69037.1 - 0.00048 19.9 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.13 CDO69037.1 - 0.0055 16.3 2.5 0.013 15.1 2.5 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region zf-C2H2_jaz PF12171.8 CDO69037.1 - 0.0072 16.6 0.5 0.014 15.7 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDO69037.1 - 0.067 13.5 0.3 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CDO69037.1 - 0.27 11.0 0.5 0.48 10.2 0.5 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type NDUF_B4 PF07225.12 CDO69038.1 - 0.002 18.0 0.0 0.0023 17.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF2545 PF10810.8 CDO69038.1 - 0.049 13.8 0.1 0.067 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) COQ7 PF03232.13 CDO69039.1 - 1.4e-68 230.1 0.1 1.7e-68 229.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 NUT PF12881.7 CDO69039.1 - 0.028 12.9 0.4 0.037 12.5 0.4 1.1 1 0 0 1 1 1 0 NUT protein Ferritin_2 PF13668.6 CDO69039.1 - 0.028 14.6 0.1 4.1 7.6 0.0 2.4 1 1 1 2 2 2 0 Ferritin-like domain WD40 PF00400.32 CDO69041.1 - 1.8e-36 123.5 23.4 2.7e-08 34.3 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 CDO69041.1 - 5.2e-12 45.5 0.2 1.1e-11 44.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO69041.1 - 6e-10 38.8 0.1 1.2e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 CDO69041.1 - 3.5e-05 22.7 10.2 0.12 11.0 0.1 4.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 F-box_4 PF15966.5 CDO69041.1 - 0.00079 19.3 0.2 0.0037 17.1 0.0 2.2 2 0 0 2 2 2 1 F-box Pkinase PF00069.25 CDO69042.1 - 9.6e-64 215.3 0.0 1.1e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69042.1 - 7.3e-25 87.7 0.0 1e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO69042.1 - 0.0011 18.9 0.3 0.037 13.9 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDO69042.1 - 0.0037 16.6 0.0 0.0086 15.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 CDO69042.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 CDO69042.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 COG4 PF08318.12 CDO69043.1 - 2.8e-79 266.6 0.0 4.1e-79 266.1 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 CDO69043.1 - 0.016 14.1 0.0 0.035 13.0 0.0 1.5 1 0 0 1 1 1 0 RINT-1 / TIP-1 family DUF948 PF06103.11 CDO69043.1 - 1.1 9.6 3.1 1.7 9.0 0.2 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Snf7 PF03357.21 CDO69044.1 - 3.5e-34 117.9 17.5 1.6e-33 115.7 15.1 2.6 2 1 0 2 2 2 1 Snf7 KfrA_N PF11740.8 CDO69044.1 - 0.2 12.3 6.9 0.54 10.9 0.8 2.9 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term DUF4208 PF13907.6 CDO69044.1 - 0.66 10.5 4.5 18 5.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) YlqD PF11068.8 CDO69044.1 - 1.1 9.6 13.1 4.4 7.7 4.3 2.3 1 1 0 2 2 2 0 YlqD protein Resolvase PF00239.21 CDO69044.1 - 1.3 9.1 9.4 5.5 7.1 3.1 3.0 2 1 0 2 2 2 0 Resolvase, N terminal domain TPR_MLP1_2 PF07926.12 CDO69044.1 - 6 7.0 12.9 6.1 6.9 0.1 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein zf-AN1 PF01428.16 CDO69045.1 - 7.6e-17 61.2 16.3 1.7e-09 37.7 2.6 2.7 2 1 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 CDO69045.1 - 0.015 15.5 3.1 0.015 15.5 3.1 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Myosin_head PF00063.21 CDO69046.1 - 4.7e-259 861.2 0.6 9.5e-259 860.2 0.0 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 CDO69046.1 - 3.3e-27 94.8 1.2 3.3e-27 94.8 1.2 3.2 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 CDO69046.1 - 1.5e-13 49.2 41.8 0.0011 18.6 0.9 7.5 7 0 0 7 7 7 5 IQ calmodulin-binding motif Myosin_N PF02736.19 CDO69046.1 - 0.0013 18.6 0.2 0.0027 17.5 0.2 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain TPR_MLP1_2 PF07926.12 CDO69046.1 - 0.0071 16.4 11.2 0.0071 16.4 11.2 2.8 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein AAA_22 PF13401.6 CDO69046.1 - 0.0077 16.5 1.2 0.029 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain BET PF17035.5 CDO69046.1 - 0.016 15.4 3.2 5.8 7.2 0.0 4.0 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation AAA_16 PF13191.6 CDO69046.1 - 0.094 13.1 0.0 0.094 13.1 0.0 3.5 2 1 0 2 2 2 0 AAA ATPase domain Golgin_A5 PF09787.9 CDO69046.1 - 0.11 12.0 25.7 0.22 10.9 25.7 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 CDO69046.1 - 0.88 9.8 12.9 4.4 7.5 12.2 2.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Bestrophin PF01062.21 CDO69047.1 - 4.2e-29 101.9 0.0 3.1e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel 2Fe-2S_thioredx PF01257.19 CDO69048.1 - 8.5e-58 194.3 0.0 1.1e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DDE_3 PF13358.6 CDO69049.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 CDO69050.1 - 1.3e-09 38.0 0.1 1.2e-08 34.8 0.0 2.5 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CDO69050.1 - 2.5e-09 37.0 0.2 2.4e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain TFIIA PF03153.13 CDO69050.1 - 0.025 14.6 13.8 0.036 14.1 13.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plavaka PF18759.1 CDO69052.1 - 3.5e-46 157.9 0.1 4e-46 157.7 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase Cas_Cas1 PF01867.16 CDO69052.1 - 0.038 13.1 0.0 0.047 12.8 0.0 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas1 TPP_enzyme_N PF02776.18 CDO69055.1 - 3.8e-36 124.3 0.1 6.6e-36 123.5 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CDO69055.1 - 1.5e-18 66.9 0.0 2.8e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CDO69055.1 - 1.1e-13 51.3 0.0 2.9e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF362 PF04015.12 CDO69055.1 - 0.1 12.8 0.2 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF362) Ras PF00071.22 CDO69058.1 - 7.9e-34 116.6 0.2 9.4e-34 116.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO69058.1 - 4.6e-25 88.2 0.2 8.5e-25 87.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO69058.1 - 4.3e-08 32.8 0.1 6.7e-08 32.2 0.1 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDO69058.1 - 2.4e-07 30.4 0.2 3e-07 30.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 CDO69058.1 - 0.015 14.7 0.0 1.5 8.2 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein DLIC PF05783.11 CDO69058.1 - 0.017 14.0 0.4 1.8 7.3 0.0 2.1 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 CDO69058.1 - 0.058 12.6 2.2 0.14 11.3 0.1 2.2 2 1 1 3 3 3 0 G-protein alpha subunit Glyco_hydro_18 PF00704.28 CDO69059.1 - 1.8e-69 234.8 10.3 5.1e-68 230.1 10.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 CDO69059.1 - 0.001 19.5 6.0 0.001 19.5 6.0 2.8 2 0 0 2 2 2 1 Carbohydrate binding domain PknH_C PF14032.6 CDO69059.1 - 0.14 12.0 4.0 0.28 11.0 2.5 2.1 1 1 1 2 2 2 0 PknH-like extracellular domain Glyco_hydro_18 PF00704.28 CDO69060.1 - 5.4e-77 259.6 8.3 5.4e-77 259.6 8.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 CDO69060.1 - 0.031 14.9 8.5 0.14 12.8 8.5 2.3 1 0 0 1 1 1 0 Carbohydrate binding domain DUF572 PF04502.13 CDO69060.1 - 1.8 8.1 19.7 2.8 7.5 19.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF936 PF06075.12 CDO69060.1 - 2.3 7.1 27.8 3.1 6.6 27.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) rRNA_proc-arch PF13234.6 CDO69061.1 - 1.8e-91 306.9 0.0 3.7e-91 305.8 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 CDO69061.1 - 1.3e-54 184.2 0.6 3.3e-54 183.0 0.6 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CDO69061.1 - 3.8e-14 52.8 0.4 2e-10 40.7 0.1 3.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO69061.1 - 1.4e-07 31.8 0.0 1e-06 29.1 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO69061.1 - 0.022 14.8 0.1 5 7.1 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 CDO69061.1 - 0.03 13.4 0.0 0.074 12.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AroM PF07302.11 CDO69061.1 - 0.095 12.1 0.1 1.9 7.8 0.0 2.7 2 0 0 2 2 2 0 AroM protein MutS_III PF05192.18 CDO69061.1 - 0.13 12.5 0.0 3.5 7.8 0.1 2.5 2 1 0 2 2 2 0 MutS domain III CBM_20 PF00686.19 CDO69062.1 - 4.4e-32 109.8 0.1 7.9e-32 109.0 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.24 CDO69062.1 - 3.9e-14 53.0 0.1 2.7e-13 50.2 0.1 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 CDO69062.1 - 2.4e-13 50.3 0.0 8.3e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain FAD_binding_3 PF01494.19 CDO69064.1 - 2.4e-74 250.7 0.0 3.3e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CDO69064.1 - 1.6e-08 34.1 4.1 4.4e-05 22.9 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDO69064.1 - 4.3e-07 29.0 1.4 6.1e-06 25.2 0.3 2.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 CDO69064.1 - 1.2e-06 28.4 3.6 1.8e-05 24.5 0.4 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDO69064.1 - 1.3e-06 27.8 1.1 1.3e-06 27.8 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CDO69064.1 - 1e-05 25.7 0.3 2.5e-05 24.4 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CDO69064.1 - 1.4e-05 24.4 0.1 2.5e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CDO69064.1 - 1.8e-05 25.2 2.6 0.23 12.0 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDO69064.1 - 2e-05 24.0 0.3 0.00035 19.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CDO69064.1 - 3.8e-05 22.7 0.1 7.8e-05 21.7 0.1 1.5 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.7 CDO69064.1 - 0.00026 20.5 0.8 0.00026 20.5 0.8 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CDO69064.1 - 0.00082 18.6 0.8 0.0014 17.8 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 CDO69064.1 - 0.0073 16.3 1.3 0.8 9.7 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CDO69064.1 - 0.018 14.1 0.3 0.052 12.6 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 CDO69064.1 - 0.053 12.8 1.3 6.2 6.0 0.1 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 CDO69064.1 - 0.074 13.5 0.1 0.16 12.5 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 CDO69064.1 - 0.1 12.2 1.1 0.68 9.6 0.3 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Tocopherol_cycl PF14249.6 CDO69066.1 - 1.6e-07 30.8 0.1 1.5e-06 27.6 0.1 2.1 2 0 0 2 2 2 2 Tocopherol cyclase Cys_Met_Meta_PP PF01053.20 CDO69068.1 - 1.6e-47 161.9 0.2 2.9e-32 111.6 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CDO69068.1 - 0.03 13.6 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FMN_red PF03358.15 CDO69069.1 - 1.1e-06 28.4 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CDO69069.1 - 0.00046 20.0 0.0 0.00063 19.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 CDO69069.1 - 0.12 12.6 0.0 0.86 9.8 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin COG7 PF10191.9 CDO69070.1 - 6.7e-70 236.3 1.2 1.1e-45 156.2 0.3 4.0 4 0 0 4 4 4 4 Golgi complex component 7 (COG7) ETC_C1_NDUFA5 PF04716.14 CDO69070.1 - 0.11 12.3 0.0 0.42 10.5 0.0 2.0 1 0 0 1 1 1 0 ETC complex I subunit conserved region Vps53_N PF04100.12 CDO69070.1 - 0.14 11.1 1.5 0.27 10.1 1.5 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal eIF3g PF12353.8 CDO69071.1 - 8.5e-29 100.5 2.6 2.8e-27 95.6 0.4 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CDO69071.1 - 9.7e-19 67.0 0.1 1.6e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDO69071.1 - 0.00073 19.5 0.3 0.12 12.4 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 CDO69071.1 - 0.034 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CDO69071.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OAM_alpha PF16552.5 CDO69071.1 - 0.1 12.4 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 D-ornithine 4,5-aminomutase alpha-subunit PHM7_cyt PF14703.6 CDO69071.1 - 0.22 11.7 0.3 5.1 7.3 0.2 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter TraE PF05309.11 CDO69073.1 - 0.24 10.7 0.1 0.24 10.7 0.1 2.0 2 0 0 2 2 2 0 TraE protein Rad60-SLD_2 PF13881.6 CDO69074.1 - 2.1e-12 47.1 0.0 2.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDO69074.1 - 0.0024 17.6 0.0 0.016 14.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family PGI PF00342.19 CDO69075.1 - 2.4e-235 781.7 0.3 3e-235 781.4 0.3 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Cu_amine_oxid PF01179.20 CDO69076.1 - 4e-128 427.8 0.0 5.7e-128 427.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 CDO69076.1 - 6.8e-09 35.4 0.1 2.2e-08 33.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 CDO69076.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Pro-kuma_activ PF09286.11 CDO69077.1 - 1.7e-34 119.2 0.0 3e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO69077.1 - 3.5e-06 26.5 0.0 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Epimerase PF01370.21 CDO69078.1 - 9.6e-11 41.6 0.0 2.6e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CDO69078.1 - 2.3e-10 40.1 0.0 4.9e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 CDO69078.1 - 5.6e-07 29.3 0.2 1e-05 25.1 0.2 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDO69078.1 - 1.3e-05 24.3 0.0 0.0003 19.9 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CDO69078.1 - 2.5e-05 24.2 0.1 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 CDO69078.1 - 0.0034 17.0 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 CDO69078.1 - 0.044 13.2 0.1 0.092 12.2 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 CDO69078.1 - 0.12 12.3 0.3 1.4 8.8 0.3 2.1 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 CDO69079.1 - 6.5e-14 52.0 0.0 4.1e-13 49.4 0.0 2.1 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO69079.1 - 8.7e-12 44.6 0.0 1.9e-11 43.5 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CDO69079.1 - 3e-09 36.7 1.5 3.8e-09 36.4 0.1 1.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CDO69079.1 - 4.5e-08 33.2 0.1 8e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CDO69079.1 - 3.7e-07 29.6 0.1 2e-05 23.9 0.1 2.8 3 1 0 3 3 3 1 Male sterility protein NmrA PF05368.13 CDO69079.1 - 0.00071 19.2 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 CDO69079.1 - 0.0014 18.1 0.5 0.0024 17.3 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CDO69079.1 - 0.06 13.3 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 CDO69079.1 - 0.088 11.9 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 CDO69079.1 - 0.1 12.9 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Citrate_bind PF16114.5 CDO69080.1 - 4.4e-91 303.2 0.0 6.9e-91 302.6 0.0 1.3 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 CDO69080.1 - 2.4e-19 69.7 0.0 9.1e-17 61.2 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 CDO69080.1 - 3.2e-08 34.1 0.0 7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 CDO69080.1 - 2.9e-07 30.3 0.0 5.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain DUF1275 PF06912.11 CDO69081.1 - 7e-30 104.4 19.7 8.9e-30 104.0 19.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Epimerase PF01370.21 CDO69082.1 - 9.1e-11 41.7 0.0 1.5e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CDO69082.1 - 7.8e-07 29.2 0.1 1.5e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CDO69082.1 - 1.2e-05 24.5 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CDO69082.1 - 0.00023 20.7 0.0 0.009 15.4 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CDO69082.1 - 0.0012 18.1 0.0 0.045 12.9 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 CDO69082.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CDO69083.1 - 6.5e-17 61.8 0.0 9.7e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO69083.1 - 1.3e-12 47.3 0.0 1.8e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CDO69083.1 - 2.1e-10 40.8 0.9 3.5e-10 40.1 0.9 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CDO69083.1 - 5.1e-09 35.7 0.2 8.5e-08 31.7 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 CDO69083.1 - 6.1e-09 35.7 0.0 1.7e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CDO69083.1 - 9.6e-07 28.6 0.2 1.8e-06 27.7 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 CDO69083.1 - 0.00017 20.8 0.1 0.00026 20.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 CDO69083.1 - 0.0072 16.3 0.2 0.14 12.1 0.2 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 CDO69083.1 - 0.015 14.7 1.7 0.015 14.7 0.1 1.8 2 1 0 2 2 2 0 short chain dehydrogenase Epimerase PF01370.21 CDO69084.1 - 1e-16 61.2 0.0 1.5e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO69084.1 - 2.4e-13 49.8 0.0 3.5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CDO69084.1 - 4.1e-10 39.3 0.1 4.6e-09 35.8 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CDO69084.1 - 1.7e-09 37.8 0.6 2.6e-09 37.2 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CDO69084.1 - 1.3e-08 34.6 0.1 2.7e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CDO69084.1 - 3.6e-06 26.7 0.2 5.2e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 CDO69084.1 - 0.00016 20.9 0.2 0.00022 20.4 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 CDO69084.1 - 0.0011 18.5 0.2 0.0022 17.5 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO69084.1 - 0.0046 16.9 0.2 0.033 14.1 0.2 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 CDO69084.1 - 0.12 11.9 0.6 0.26 10.8 0.2 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.25 CDO69085.1 - 2.3e-50 171.4 0.0 3.5e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69085.1 - 6.6e-25 87.9 0.0 3.3e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO69085.1 - 4.6e-05 22.4 0.0 0.00019 20.4 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 CDO69085.1 - 0.001 19.1 0.2 0.0045 16.9 0.2 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CDO69085.1 - 0.0015 18.2 0.0 0.29 10.7 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CDO69085.1 - 0.0093 15.3 0.0 0.052 12.9 0.0 2.0 1 1 0 1 1 1 1 Kinase-like SH3_16 PF18348.1 CDO69085.1 - 0.1 12.4 0.7 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 Bacterial dipeptidyl-peptidase Sh3 domain Kdo PF06293.14 CDO69085.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pro-kuma_activ PF09286.11 CDO69086.1 - 6.7e-34 117.2 0.0 1.5e-33 116.1 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO69086.1 - 1.6e-07 30.9 0.3 2.6e-07 30.2 0.3 1.2 1 0 0 1 1 1 1 Subtilase family F-box-like PF12937.7 CDO69087.1 - 1.5e-09 37.6 3.1 4.2e-09 36.2 3.1 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 CDO69089.1 - 1.4e-17 63.7 24.4 2.4e-17 62.9 23.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO69089.1 - 1.6e-16 59.9 4.6 1.6e-16 59.9 4.6 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Hydrolase_4 PF12146.8 CDO69090.1 - 8.9e-49 165.9 0.0 1e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO69090.1 - 4.5e-15 56.9 0.2 5.5e-15 56.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDO69090.1 - 4.3e-10 39.7 0.1 6.6e-10 39.1 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 CDO69090.1 - 4.7e-05 23.0 0.0 0.00015 21.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF1749 PF08538.10 CDO69090.1 - 0.00028 20.1 0.0 0.00044 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) PGAP1 PF07819.13 CDO69090.1 - 0.0012 18.7 0.0 0.082 12.6 0.0 2.4 3 0 0 3 3 3 1 PGAP1-like protein Lipase_3 PF01764.25 CDO69090.1 - 0.002 18.0 0.1 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_2 PF02230.16 CDO69090.1 - 0.0045 16.8 0.0 7.8 6.2 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CDO69090.1 - 0.051 13.0 0.0 5.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3089 PF11288.8 CDO69090.1 - 0.051 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Thioesterase PF00975.20 CDO69090.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain DUF368 PF04018.13 CDO69091.1 - 0.079 12.5 0.1 0.09 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF368) BCS1_N PF08740.11 CDO69092.1 - 3.1e-25 89.2 2.8 8.6e-17 61.7 0.5 2.6 2 1 1 3 3 3 2 BCS1 N terminal AAA PF00004.29 CDO69092.1 - 1.3e-11 45.0 0.0 1.8e-10 41.4 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) YlbE PF14003.6 CDO69092.1 - 6.3e-05 23.3 0.1 0.00014 22.2 0.1 1.5 1 0 0 1 1 1 1 YlbE-like protein RuvB_N PF05496.12 CDO69092.1 - 0.00065 19.5 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDO69092.1 - 0.0083 16.5 1.4 0.013 15.9 0.2 2.2 3 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CDO69092.1 - 0.013 14.7 0.0 0.05 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 CDO69092.1 - 0.016 15.4 0.0 0.06 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CDO69092.1 - 0.016 15.2 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CDO69092.1 - 0.022 14.0 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 CDO69092.1 - 0.06 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 CDO69092.1 - 0.1 12.1 0.6 0.36 10.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 CDO69092.1 - 0.16 12.2 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDO69092.1 - 0.17 12.3 0.0 5.8 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Pantoate_ligase PF02569.15 CDO69093.1 - 1.7e-41 142.2 0.0 2.3e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase UCR_Fe-S_N PF10399.9 CDO69093.1 - 0.011 15.0 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Glyco_hydro_71 PF03659.14 CDO69094.1 - 6.5e-82 275.3 13.9 1.6e-78 264.2 13.9 3.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 NUDE_C PF04880.13 CDO69094.1 - 1 9.8 4.7 1.8 9.0 4.7 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region LANC_like PF05147.13 CDO69095.1 - 9.9e-11 40.8 0.0 2.6e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Glyoxal_oxid_N PF07250.11 CDO69096.1 - 2.2e-29 102.4 0.3 4.6e-12 45.6 0.0 4.1 3 1 1 4 4 4 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CDO69096.1 - 2.1e-22 79.2 0.1 3.7e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 CDO69096.1 - 0.0017 18.3 0.1 0.15 12.1 0.1 3.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Big_11 PF18200.1 CDO69096.1 - 0.026 14.4 0.1 0.093 12.7 0.1 1.9 1 0 0 1 1 1 0 Bacterial Ig-like domain Herpes_gE PF02480.16 CDO69096.1 - 0.19 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Peptidase_S9 PF00326.21 CDO69097.1 - 0.0023 17.4 0.0 0.0053 16.3 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CDO69097.1 - 0.031 13.6 0.2 5.8 6.1 0.1 3.1 2 1 0 3 3 3 0 Serine aminopeptidase, S33 PhoPQ_related PF10142.9 CDO69097.1 - 0.1 11.2 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Peptidase_S37 PF05576.11 CDO69097.1 - 0.12 11.0 0.1 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 Plavaka PF18759.1 CDO69098.1 - 3.1e-126 421.0 0.0 4.6e-126 420.4 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase MFS_1 PF07690.16 CDO69098.1 - 1.5e-16 60.3 34.0 3.9e-12 45.8 34.0 3.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO69098.1 - 4.1e-10 38.7 5.0 4.1e-10 38.7 5.0 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PIP5K PF01504.18 CDO69100.1 - 1.3e-102 342.7 0.0 2.4e-102 341.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cnd1 PF12717.7 CDO69101.1 - 1.1e-52 178.3 6.0 6e-50 169.4 0.4 3.7 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CDO69101.1 - 3.2e-49 167.0 0.4 3.2e-49 167.0 0.4 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 CDO69101.1 - 9.9e-08 32.3 1.7 0.018 15.4 0.0 4.6 4 0 0 4 4 4 2 HEAT repeats Adaptin_N PF01602.20 CDO69101.1 - 8.5e-06 24.6 5.4 0.0047 15.6 0.2 4.0 3 2 1 4 4 4 2 Adaptin N terminal region HEAT PF02985.22 CDO69101.1 - 1e-05 25.3 9.0 0.65 10.4 0.2 6.7 7 0 0 7 7 7 2 HEAT repeat RTP1_C1 PF10363.9 CDO69101.1 - 2.7e-05 24.3 1.5 0.59 10.3 0.0 4.0 2 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 ENTH PF01417.20 CDO69101.1 - 0.0011 19.1 1.1 4 7.5 0.1 3.9 4 0 0 4 4 4 2 ENTH domain Cnd3 PF12719.7 CDO69101.1 - 0.017 14.3 6.5 0.026 13.7 0.3 3.5 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain YtzH PF14165.6 CDO69101.1 - 0.019 15.4 1.4 0.82 10.1 0.0 4.1 3 1 1 4 4 4 0 YtzH-like protein FKS1_dom1 PF14288.6 CDO69101.1 - 0.028 14.7 0.2 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 PqqD PF05402.12 CDO69101.1 - 0.15 12.4 0.4 3.9 7.9 0.0 3.3 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) HEAT_EZ PF13513.6 CDO69101.1 - 4.2 8.0 8.3 83 3.8 0.1 4.9 6 0 0 6 6 4 0 HEAT-like repeat RNA_pol_N PF01194.17 CDO69102.1 - 2.2e-31 107.9 0.3 2.6e-31 107.7 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Oxidored_FMN PF00724.20 CDO69103.1 - 1.4e-21 77.2 0.0 1e-14 54.6 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 CDO69103.1 - 0.0023 17.1 0.0 0.0034 16.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Nitro_FeMo-Co PF02579.17 CDO69103.1 - 0.024 15.0 0.2 2.8 8.3 0.0 2.8 2 1 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor FMN_dh PF01070.18 CDO69103.1 - 0.12 11.4 0.6 0.17 10.9 0.6 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase adh_short PF00106.25 CDO69104.1 - 8.9e-12 44.9 0.0 1.3e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69104.1 - 5.5e-08 32.7 0.0 8.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2706 PF10913.8 CDO69104.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) adh_short PF00106.25 CDO69105.1 - 2.6e-23 82.5 0.1 4.8e-23 81.6 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69105.1 - 1.6e-15 57.3 0.0 3.8e-14 52.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO69105.1 - 6.6e-05 22.9 0.2 0.00028 20.9 0.1 1.9 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.6 CDO69105.1 - 0.00024 21.0 0.1 0.00073 19.5 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 CDO69106.1 - 1.6e-31 109.3 0.0 1.9e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69106.1 - 9.2e-21 74.5 0.0 1.1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO69106.1 - 4.2e-09 36.6 0.0 5.2e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDO69106.1 - 1.2e-05 25.3 0.1 3.2e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 CDO69106.1 - 0.00031 20.3 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CDO69106.1 - 0.0057 15.9 0.0 0.031 13.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CDO69107.1 - 2.8e-24 85.7 0.1 1.3e-15 57.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69107.1 - 4.7e-14 52.5 0.1 5.5e-13 49.0 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CDO69107.1 - 3e-07 30.5 0.1 5.2e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 CDO69107.1 - 4.7e-07 29.9 0.0 8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO69107.1 - 0.00096 18.7 0.0 0.0022 17.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CDO69107.1 - 0.0027 16.9 0.0 0.047 12.9 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 CDO69107.1 - 0.053 12.6 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CDO69107.1 - 0.063 12.3 0.0 0.082 11.9 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F-box-like PF12937.7 CDO69108.1 - 0.00017 21.4 0.3 0.00057 19.7 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO69108.1 - 0.001 18.9 0.3 0.0023 17.8 0.3 1.6 1 0 0 1 1 1 1 F-box domain AAA_12 PF13087.6 CDO69109.1 - 1.4e-35 122.8 0.1 2.6e-35 121.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDO69109.1 - 2.1e-27 96.5 0.0 1.8e-26 93.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDO69109.1 - 3.3e-11 43.7 0.0 5.2e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CDO69109.1 - 7.6e-10 38.8 0.0 2.5e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain zf-CCCH_4 PF18044.1 CDO69109.1 - 4e-06 26.5 7.5 4e-06 26.5 7.5 2.4 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 CDO69109.1 - 1.6e-05 24.7 6.9 1.6e-05 24.7 6.9 2.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDO69109.1 - 0.00034 20.5 7.9 0.00034 20.5 7.9 2.7 2 0 0 2 2 2 1 Zinc finger domain DUF2075 PF09848.9 CDO69109.1 - 0.0018 17.6 0.0 0.46 9.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 CDO69109.1 - 0.005 16.4 0.1 0.035 13.6 0.1 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain ATPase PF06745.13 CDO69109.1 - 0.011 15.2 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 KaiC UvrD_C_2 PF13538.6 CDO69109.1 - 0.034 14.0 0.0 0.13 12.2 0.0 2.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 CDO69109.1 - 0.036 14.5 0.0 0.092 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDO69109.1 - 0.039 14.5 0.0 0.23 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDO69109.1 - 0.061 13.7 0.1 0.47 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 CDO69109.1 - 0.09 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 CDO69109.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Torus PF16131.5 CDO69109.1 - 0.15 12.8 0.5 8.2 7.2 0.0 2.7 2 0 0 2 2 2 0 Torus domain AAA_5 PF07728.14 CDO69109.1 - 0.15 12.1 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_10 PF00331.20 CDO69110.1 - 3.8e-93 312.1 0.0 4.7e-93 311.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 adh_short PF00106.25 CDO69111.1 - 2.3e-27 95.7 0.0 2.8e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69111.1 - 5.6e-19 68.6 0.1 7.2e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO69111.1 - 2.5e-09 37.3 0.1 3.2e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDO69111.1 - 0.00013 21.9 0.1 0.0004 20.3 0.0 1.7 1 1 1 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CDO69111.1 - 0.16 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 CDO69112.1 - 2.8e-31 108.5 0.1 3.5e-31 108.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69112.1 - 7.5e-23 81.3 0.0 9.2e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO69112.1 - 1.6e-08 34.7 0.1 3.3e-08 33.6 0.1 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDO69112.1 - 8.6e-07 29.0 0.1 2e-06 27.8 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 CDO69112.1 - 0.00023 20.7 0.4 0.00053 19.5 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDO69112.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 CDO69112.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 CDO69112.1 - 0.18 12.0 0.7 1.5 9.1 0.7 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain APH PF01636.23 CDO69113.1 - 0.0012 18.8 0.1 0.0037 17.2 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family NMD3 PF04981.13 CDO69114.1 - 1.5e-80 270.2 0.4 1.9e-80 269.9 0.4 1.1 1 0 0 1 1 1 1 NMD3 family NinF PF05810.12 CDO69114.1 - 0.038 13.8 1.9 0.18 11.7 0.7 2.6 3 0 0 3 3 3 0 NinF protein Rpr2 PF04032.16 CDO69114.1 - 0.048 13.9 2.4 6.6 7.1 0.1 2.8 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 CDO69114.1 - 0.066 13.2 6.0 0.21 11.6 2.9 2.7 1 1 1 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 CDO69114.1 - 1.3 9.0 9.0 1.4 8.9 0.5 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) CLN3 PF02487.17 CDO69115.1 - 2e-64 218.1 0.0 3.5e-64 217.3 0.0 1.3 1 1 0 1 1 1 1 CLN3 protein DUF3755 PF12579.8 CDO69117.1 - 0.022 14.4 2.6 0.22 11.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3755) DUF4363 PF14276.6 CDO69117.1 - 0.036 14.2 0.1 0.72 10.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) DUF722 PF05263.11 CDO69117.1 - 0.04 14.1 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF722) PI_PP_I PF18363.1 CDO69117.1 - 0.15 12.3 0.1 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Bim_N PF06773.11 CDO69118.1 - 0.024 14.3 0.3 0.068 12.9 0.3 1.7 1 0 0 1 1 1 0 Bim protein N-terminus Retrotran_gag_2 PF14223.6 CDO69119.1 - 8.4e-27 93.5 0.0 1.4e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 CDO69119.1 - 4.1e-13 49.6 0.0 9.4e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO69119.1 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 CDO69119.1 - 3.6e-07 29.7 0.6 1e-06 28.2 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 CDO69119.1 - 1.7e-05 24.5 0.1 3.5e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO69119.1 - 0.0092 16.0 3.0 0.024 14.7 3.0 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDO69119.1 - 0.011 15.4 1.2 0.025 14.3 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle ING PF12998.7 CDO69121.1 - 5e-14 52.7 0.7 9.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.6 CDO69121.1 - 0.0025 17.3 1.8 0.0052 16.3 1.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 CDO69121.1 - 0.014 15.3 7.8 0.027 14.3 0.8 2.4 2 0 0 2 2 2 0 PHD-finger Nuf2 PF03800.14 CDO69122.1 - 1.4e-34 119.2 0.0 4e-34 117.7 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 CDO69122.1 - 9.6e-29 99.8 17.9 9.6e-29 99.8 17.9 4.1 3 2 2 5 5 5 1 Designed helical repeat protein 10 domain DUF3584 PF12128.8 CDO69122.1 - 0.0019 15.8 35.0 0.0026 15.4 35.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Spc7 PF08317.11 CDO69122.1 - 0.097 11.5 36.3 0.046 12.6 9.5 3.3 1 1 1 3 3 3 0 Spc7 kinetochore protein APG6_N PF17675.1 CDO69122.1 - 0.11 13.0 40.8 0.13 12.8 8.6 4.2 1 1 2 3 3 3 0 Apg6 coiled-coil region HALZ PF02183.18 CDO69122.1 - 0.3 11.3 7.6 6.4 7.1 0.0 4.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF3450 PF11932.8 CDO69122.1 - 0.31 10.3 35.1 0.64 9.3 10.0 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) Lipoprotein_6 PF01441.19 CDO69122.1 - 0.42 10.6 6.5 3.6 7.6 0.2 3.2 1 1 1 3 3 3 0 Lipoprotein DASH_Duo1 PF08651.10 CDO69122.1 - 0.49 10.2 4.4 1.4 8.8 0.7 3.2 2 1 0 2 2 2 0 DASH complex subunit Duo1 Filament PF00038.21 CDO69122.1 - 0.62 9.6 38.5 0.53 9.8 16.4 3.1 1 1 2 3 3 3 0 Intermediate filament protein DUF1664 PF07889.12 CDO69122.1 - 2 8.4 25.1 0.11 12.6 1.9 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 CDO69122.1 - 2.4 8.9 24.0 3.5 8.3 2.2 3.9 2 2 2 4 4 4 0 Initiation control protein YabA Scaffolding_pro PF11418.8 CDO69122.1 - 5.4 7.6 10.6 2.8 8.6 0.6 2.9 2 2 1 3 3 3 0 Phi29 scaffolding protein Helicase_C PF00271.31 CDO69123.1 - 1.1e-18 67.5 0.0 4.5e-18 65.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDO69123.1 - 1.5e-15 57.4 0.0 3.8e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 CDO69123.1 - 1.8e-12 47.1 0.0 4.4e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 RQC domain RecQ_Zn_bind PF16124.5 CDO69123.1 - 3.2e-08 34.2 5.1 7.8e-08 32.9 5.1 1.7 1 0 0 1 1 1 1 RecQ zinc-binding DUF1156 PF06634.12 CDO69126.1 - 0.0013 18.8 0.3 0.0026 17.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1156) Retrotrans_gag PF03732.17 CDO69127.1 - 2.5e-08 34.1 0.0 5.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein LSM PF01423.22 CDO69129.1 - 4.5e-15 55.1 1.2 5e-15 55.0 0.3 1.5 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 CDO69129.1 - 0.034 14.3 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Voltage_CLC PF00654.20 CDO69130.1 - 1.4e-71 241.6 24.8 4.8e-70 236.6 22.1 2.6 2 1 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 CDO69130.1 - 0.0066 16.9 0.0 3.7 8.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain E1-E2_ATPase PF00122.20 CDO69130.1 - 0.8 9.2 0.0 0.8 9.2 0.0 2.8 4 0 0 4 4 4 0 E1-E2 ATPase DUF3506 PF12014.8 CDO69131.1 - 1.3e-10 41.4 0.0 5.4e-09 36.2 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.33 CDO69131.1 - 0.0082 16.0 0.3 0.016 15.1 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO69131.1 - 0.036 14.0 0.2 0.092 12.7 0.2 1.7 1 0 0 1 1 1 0 F-box-like Retrotran_gag_2 PF14223.6 CDO69132.1 - 2.1e-16 59.8 0.1 5.7e-15 55.2 0.0 2.2 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 CDO69132.1 - 0.0042 16.8 1.5 0.0073 16.0 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CDO69132.1 - 0.0079 16.2 3.0 0.0079 16.2 3.0 1.8 2 0 0 2 2 2 1 Zinc knuckle Abhydrolase_1 PF00561.20 CDO69133.1 - 7.2e-09 35.7 0.1 1.1e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO69133.1 - 0.015 15.9 0.1 0.018 15.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribosom_S12_S23 PF00164.25 CDO69134.1 - 2.4e-49 165.7 1.1 3e-49 165.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CTP_transf_1 PF01148.20 CDO69135.1 - 7.6e-73 245.5 20.7 1e-72 245.1 20.7 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Topoisom_I_N PF02919.15 CDO69136.1 - 4.2e-98 327.1 0.7 4.2e-98 327.1 0.7 3.7 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 CDO69136.1 - 3.7e-80 268.5 10.7 9.9e-56 188.6 0.9 3.3 2 2 1 3 3 3 2 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 CDO69136.1 - 4.6e-38 129.0 2.4 1.4e-37 127.4 0.6 2.7 2 0 0 2 2 2 1 C-terminal topoisomerase domain STIL_N PF15253.6 CDO69136.1 - 0.3 10.0 3.2 0.64 8.9 2.5 1.8 2 0 0 2 2 2 0 SCL-interrupting locus protein N-terminus DUF2115 PF09888.9 CDO69136.1 - 6.3 7.3 10.9 2.7 8.5 6.9 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) NDUF_B12 PF08122.12 CDO69137.1 - 4.3e-20 71.5 0.4 5.8e-20 71.1 0.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ESSS PF10183.9 CDO69137.1 - 5.5 7.3 5.5 52 4.1 5.4 2.3 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PALP PF00291.25 CDO69138.1 - 1.3e-80 271.0 0.1 2.5e-80 270.0 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CDO69138.1 - 4e-44 148.3 0.0 2.3e-25 88.2 0.0 2.6 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase PHD PF00628.29 CDO69138.1 - 8.5e-09 35.2 10.3 1.5e-08 34.4 10.3 1.4 1 0 0 1 1 1 1 PHD-finger DUF4559 PF15112.6 CDO69138.1 - 0.3 10.7 1.8 0.53 9.9 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) zf-CW PF07496.15 CDO69138.1 - 0.87 9.7 3.5 1.8 8.7 3.5 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger Vps8 PF12816.7 CDO69139.1 - 1.2e-67 227.3 0.0 1.6e-66 223.6 0.0 2.5 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 CDO69139.1 - 0.00015 21.6 0.0 0.039 13.8 0.0 3.3 3 0 0 3 3 3 1 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 CDO69139.1 - 0.026 14.8 0.0 1.2 9.5 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3510 PF12022.8 CDO69140.1 - 1.4e-30 106.3 1.3 3.3e-30 105.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 CDO69140.1 - 7.1e-27 94.1 1.7 2.7e-26 92.2 1.7 2.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 PEPcase PF00311.17 CDO69140.1 - 0.0017 16.6 1.2 0.0039 15.3 1.2 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Spc7 PF08317.11 CDO69140.1 - 0.006 15.5 1.9 0.012 14.5 1.9 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Vps51 PF08700.11 CDO69140.1 - 0.0076 16.3 0.4 0.03 14.4 0.4 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Zw10 PF06248.13 CDO69140.1 - 0.026 13.1 2.9 0.053 12.1 0.7 2.0 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Baculo_PEP_C PF04513.12 CDO69140.1 - 0.092 12.8 0.3 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glutaredoxin PF00462.24 CDO69141.1 - 1.6e-13 50.7 0.0 3.5e-13 49.6 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 CDO69141.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO69141.1 - 0.028 14.7 0.0 0.12 12.6 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Cupin_2 PF07883.11 CDO69142.1 - 5.4e-14 51.6 0.2 8.4e-14 51.0 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 CDO69142.1 - 2e-05 24.2 0.0 5.4e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 CDO69142.1 - 0.0007 19.2 0.1 0.00091 18.9 0.1 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 CDO69142.1 - 0.0058 16.8 0.0 0.008 16.4 0.0 1.4 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 CDO69142.1 - 0.0069 16.1 0.0 0.0076 16.0 0.0 1.1 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 CDO69142.1 - 0.028 14.3 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase AraC_binding PF02311.19 CDO69142.1 - 0.028 14.3 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain JmjC PF02373.22 CDO69142.1 - 0.057 13.8 0.0 0.09 13.2 0.0 1.3 1 0 0 1 1 1 0 JmjC domain, hydroxylase HERV-K_REC PF15695.5 CDO69142.1 - 0.18 11.9 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Rec (regulator of expression encoded by corf) of HERV-K-113 Peptidase_S8 PF00082.22 CDO69143.1 - 5.7e-37 127.6 0.1 8.8e-37 127.0 0.1 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CDO69143.1 - 1.3e-10 42.0 0.1 2.5e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 CDO69143.1 - 0.0076 16.2 0.0 0.024 14.7 0.0 1.9 1 0 0 1 1 1 1 PA domain Exo_endo_phos PF03372.23 CDO69144.1 - 5.1e-21 75.2 0.1 5.6e-20 71.9 0.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 CDO69144.1 - 1.3e-14 54.0 4.5 1.1e-06 28.9 0.4 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDO69144.1 - 2.7e-13 49.5 3.2 5.4e-11 42.1 2.5 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 CDO69144.1 - 6.5e-05 22.9 2.8 13 6.8 0.1 5.5 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 CDO69144.1 - 0.028 14.5 5.8 5.8 7.2 0.3 4.3 4 0 0 4 4 4 0 Leucine Rich repeat MDD_C PF18376.1 CDO69145.1 - 3.6e-71 238.8 0.0 4.6e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CDO69145.1 - 1.7e-08 34.5 3.6 3.4e-08 33.6 3.6 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Voltage_CLC PF00654.20 CDO69146.1 - 1e-89 301.2 31.5 1.4e-89 300.8 31.5 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 CDO69146.1 - 3.7e-12 46.5 1.8 6.3e-06 26.5 0.0 2.9 3 0 0 3 3 3 2 CBS domain Phage_Coat_Gp8 PF05371.12 CDO69146.1 - 0.12 12.2 0.7 18 5.2 0.1 3.4 3 0 0 3 3 3 0 Phage major coat protein, Gp8 Retrotran_gag_2 PF14223.6 CDO69147.1 - 0.0046 16.6 0.0 0.0089 15.7 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO69147.1 - 0.13 12.4 3.4 0.22 11.6 3.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDO69147.1 - 0.15 11.9 3.0 0.26 11.1 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 CDO69148.1 - 2.1e-05 24.0 0.0 2.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69148.1 - 0.078 12.2 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Arf PF00025.21 CDO69149.1 - 1.2e-36 125.8 0.0 2.9e-36 124.6 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDO69149.1 - 1.3e-09 38.3 0.0 2.6e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CDO69149.1 - 5.2e-09 35.7 0.2 0.00031 20.0 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CDO69149.1 - 1.1e-06 28.4 0.0 1.9e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 CDO69149.1 - 1e-05 25.2 0.0 0.0029 17.2 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CDO69149.1 - 3e-05 23.5 0.0 5.5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDO69149.1 - 3.5e-05 23.3 0.0 4.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDO69149.1 - 0.00011 22.2 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CDO69149.1 - 0.00013 22.5 0.0 0.0007 20.1 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 CDO69149.1 - 0.0019 18.5 0.0 0.0048 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CDO69149.1 - 0.0024 18.4 0.2 0.0043 17.6 0.1 1.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDO69149.1 - 0.0042 16.8 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CDO69149.1 - 0.005 16.4 0.0 0.32 10.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CDO69149.1 - 0.013 15.4 0.0 0.94 9.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Thymidylate_kin PF02223.17 CDO69149.1 - 0.023 14.4 0.1 0.041 13.5 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_29 PF13555.6 CDO69149.1 - 0.034 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 CDO69149.1 - 0.036 14.0 0.1 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CDO69149.1 - 0.037 14.4 0.3 0.072 13.5 0.0 1.6 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 CDO69149.1 - 0.038 13.2 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 CDO69149.1 - 0.045 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TniB PF05621.11 CDO69149.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_33 PF13671.6 CDO69149.1 - 0.08 13.1 0.1 0.21 11.7 0.0 1.7 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CDO69149.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 CDO69149.1 - 0.13 12.9 0.2 0.19 12.3 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDO69149.1 - 0.18 11.7 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 CDO69149.1 - 0.22 11.4 0.1 0.57 10.1 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_C PF00137.21 CDO69150.1 - 1.1e-25 89.7 33.9 1.3e-15 57.4 11.6 2.6 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 CDO69150.1 - 0.22 12.0 2.2 3.5 8.1 1.1 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Oxidored_q2 PF00420.24 CDO69150.1 - 3.3 7.4 8.6 0.69 9.6 2.5 2.9 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L GPI-anchored PF10342.9 CDO69151.1 - 6.3e-06 26.9 0.0 9.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 CDO69151.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Asp PF00026.23 CDO69152.1 - 1.7e-72 244.5 9.0 6.7e-63 213.0 7.4 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO69152.1 - 3e-14 53.7 5.0 4.2e-13 49.9 5.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO69152.1 - 0.00028 21.5 0.2 0.081 13.6 0.1 3.3 2 1 0 2 2 2 1 Aspartyl protease CUE PF02845.16 CDO69153.1 - 2.6e-09 36.6 0.1 4.5e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 CUE domain FliW PF02623.15 CDO69153.1 - 0.059 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 FliW protein p47_phox_C PF08944.11 CDO69153.1 - 1.4 8.4 7.7 5.5 6.5 2.3 2.9 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain DUF3844 PF12955.7 CDO69154.1 - 7.5e-31 106.4 4.8 1.1e-30 105.9 4.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) LZ_Tnp_IS66 PF13007.7 CDO69154.1 - 0.022 15.5 0.3 0.051 14.4 0.3 1.5 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain EGF_2 PF07974.13 CDO69154.1 - 7.5 7.0 10.5 14 6.2 10.5 1.5 1 0 0 1 1 1 0 EGF-like domain Nucleoporin_FG PF13634.6 CDO69155.1 - 0.0017 19.2 5.1 0.003 18.4 5.1 1.4 1 0 0 1 1 1 1 Nucleoporin FG repeat region DUF4472 PF14739.6 CDO69155.1 - 0.009 16.7 3.8 0.012 16.3 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) DinB PF05163.12 CDO69155.1 - 0.14 12.1 1.1 0.18 11.7 1.1 1.2 1 0 0 1 1 1 0 DinB family DUF2229 PF09989.9 CDO69155.1 - 0.45 10.1 3.0 0.58 9.8 3.0 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) TFIIA PF03153.13 CDO69156.1 - 1e-56 193.8 0.0 8.4e-36 124.8 0.0 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit LapA_dom PF06305.11 CDO69157.1 - 0.054 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Gti1_Pac2 PF09729.9 CDO69158.1 - 7.2e-25 88.1 0.5 5.7e-24 85.2 0.2 1.9 1 1 1 2 2 2 1 Gti1/Pac2 family Gti1_Pac2 PF09729.9 CDO69159.1 - 8.8e-14 52.0 0.8 2.9e-13 50.3 0.0 2.1 3 0 0 3 3 3 1 Gti1/Pac2 family F-box-like PF12937.7 CDO69160.1 - 5.7e-05 22.9 2.4 6.5e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 F-box-like Rubis-subs-bind PF09273.11 CDO69162.1 - 2.9e-13 50.6 0.7 6.3e-13 49.5 0.1 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 CDO69162.1 - 1.9e-10 41.4 0.1 6.6e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 SET domain NOA36 PF06524.12 CDO69162.1 - 3.9 6.7 8.1 6.2 6.0 8.1 1.2 1 0 0 1 1 1 0 NOA36 protein TPR_19 PF14559.6 CDO69163.1 - 1.2e-29 102.6 27.5 6.4e-05 23.4 0.1 10.3 8 2 3 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 CDO69163.1 - 4.3e-26 89.6 26.0 8.8e-05 22.2 0.0 12.9 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_2 PF07719.17 CDO69163.1 - 2.2e-23 80.4 44.8 0.00051 19.9 1.9 14.5 16 1 1 17 17 15 6 Tetratricopeptide repeat TPR_14 PF13428.6 CDO69163.1 - 1.1e-16 60.1 46.0 0.013 16.2 0.3 15.1 11 4 5 16 16 15 5 Tetratricopeptide repeat TPR_16 PF13432.6 CDO69163.1 - 1.1e-14 54.8 33.3 0.011 16.4 0.0 10.5 8 2 1 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 CDO69163.1 - 8e-14 51.3 25.2 6.8e-05 23.2 0.4 11.9 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDO69163.1 - 8.5e-13 48.4 40.1 3.3e-05 24.1 2.7 10.9 8 3 4 12 12 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 CDO69163.1 - 1.2e-12 46.9 20.4 0.0032 17.6 1.0 10.7 11 1 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO69163.1 - 9.1e-10 37.9 19.0 0.16 12.0 0.1 9.4 10 1 0 10 10 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO69163.1 - 1.2e-08 35.0 13.0 0.012 15.8 0.4 6.4 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CDO69163.1 - 1.5e-08 34.5 20.8 9.2 6.9 0.0 11.9 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_4 PF07721.14 CDO69163.1 - 7.9e-06 26.0 8.1 6.6 7.7 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDO69163.1 - 0.00072 19.2 20.6 0.65 9.7 0.1 8.5 9 1 2 11 11 9 2 TPR repeat TPR_10 PF13374.6 CDO69163.1 - 0.007 16.2 34.7 0.86 9.6 0.3 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat HemY_N PF07219.13 CDO69163.1 - 0.64 10.2 0.0 0.64 10.2 0.0 5.8 5 0 0 5 5 4 0 HemY protein N-terminus Dec-1 PF04624.14 CDO69163.1 - 5 7.1 8.6 15 5.5 8.6 1.9 1 0 0 1 1 1 0 Dec-1 repeat SWIRM PF04433.17 CDO69164.1 - 1.4e-10 41.3 0.0 3.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain PALP PF00291.25 CDO69165.1 - 2.7e-49 168.2 0.1 9.8e-47 159.8 0.1 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_7 PF13241.6 CDO69165.1 - 0.026 15.0 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GHMP_kinases_C PF08544.13 CDO69165.1 - 0.13 12.6 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal CoA_binding_2 PF13380.6 CDO69166.1 - 2.3e-17 63.5 0.0 2.7e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain FBP_C PF16571.5 CDO69167.1 - 0.051 13.1 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 FBP C-terminal treble-clef zinc-finger Asp PF00026.23 CDO69168.1 - 2.8e-67 227.4 0.1 3.7e-67 227.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO69168.1 - 1.5e-14 54.6 2.7 1.2e-12 48.5 2.7 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO69168.1 - 0.071 13.8 4.6 0.13 12.9 0.7 3.3 3 2 0 3 3 3 0 Aspartyl protease EIF_2_alpha PF07541.12 CDO69169.1 - 1.1e-32 112.5 0.0 2.2e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CDO69169.1 - 2.9e-13 50.0 1.0 5.6e-13 49.0 1.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain BUD22 PF09073.10 CDO69169.1 - 0.0085 15.5 1.0 0.0085 15.5 1.0 1.9 2 0 0 2 2 2 1 BUD22 Mito_carr PF00153.27 CDO69170.1 - 1.3e-61 204.6 2.8 4.5e-20 71.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NUDIX PF00293.28 CDO69171.1 - 4.2e-16 59.2 0.1 8e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 CDO69171.1 - 4.2e-12 46.6 0.1 8.5e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 CDO69173.1 - 1.4e-18 67.2 0.1 2.5e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 CDO69173.1 - 6e-08 33.3 0.1 1.4e-07 32.1 0.1 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 CDO69173.1 - 0.00017 21.2 0.1 0.00063 19.3 0.2 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 CDO69173.1 - 0.06 13.1 0.4 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.6 CDO69173.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Nudix N-terminal DNA_ligase_ZBD PF03119.16 CDO69173.1 - 0.23 11.5 0.5 0.55 10.3 0.5 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Crr6 PF08847.11 CDO69173.1 - 0.26 10.9 0.2 0.44 10.2 0.2 1.3 1 0 0 1 1 1 0 Chlororespiratory reduction 6 AA_permease PF00324.21 CDO69174.1 - 0.21 10.2 1.9 5.5 5.5 0.6 2.0 2 0 0 2 2 2 0 Amino acid permease CRAL_TRIO PF00650.20 CDO69175.1 - 3.3e-14 52.9 0.0 4.7e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain MSC PF09402.10 CDO69175.1 - 0.28 10.6 0.7 0.4 10.1 0.7 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Metallophos PF00149.28 CDO69176.1 - 5.9e-25 89.0 0.3 1.8e-24 87.4 0.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDO69176.1 - 0.084 13.3 0.4 0.17 12.4 0.4 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain zf-C2H2 PF00096.26 CDO69177.1 - 0.01 16.3 17.8 0.015 15.7 6.1 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO69177.1 - 0.22 12.0 0.3 0.22 12.0 0.3 3.3 4 0 0 4 4 4 0 Zinc-finger double domain Lin-8 PF03353.15 CDO69177.1 - 0.48 9.9 6.1 0.74 9.3 6.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-CCCH PF00642.24 CDO69178.1 - 2e-09 37.1 2.7 4.9e-09 35.9 2.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 CDO69178.1 - 1.4e-07 31.3 5.7 2.4e-07 30.5 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO69178.1 - 1.2e-06 28.4 7.8 2.1e-06 27.6 7.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDO69178.1 - 3e-06 27.0 8.6 5.8e-06 26.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDO69178.1 - 7.2e-06 25.7 7.5 1.3e-05 24.9 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO69178.1 - 7.6e-06 25.9 6.1 1.5e-05 24.9 6.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 CDO69178.1 - 1.6e-05 24.8 4.4 3.1e-05 23.9 4.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 CDO69178.1 - 0.00011 22.3 2.6 0.00011 22.3 2.6 1.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 CDO69178.1 - 0.00018 21.8 7.1 0.00035 20.9 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 CDO69178.1 - 0.0016 18.2 2.9 0.0031 17.3 2.9 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Rtf2 PF04641.12 CDO69178.1 - 0.0067 15.8 0.4 0.0067 15.8 0.4 2.0 2 1 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 CDO69178.1 - 0.0084 16.2 7.6 0.02 15.0 7.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDO69178.1 - 0.054 13.4 6.7 0.098 12.5 6.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_L34e PF01199.18 CDO69178.1 - 0.37 11.1 2.7 0.27 11.6 0.5 1.9 2 0 0 2 2 2 0 Ribosomal protein L34e C1_2 PF03107.16 CDO69178.1 - 0.44 10.9 6.1 1.1 9.7 4.3 2.3 1 1 1 2 2 2 0 C1 domain bZIP_2 PF07716.15 CDO69179.1 - 2.3e-09 37.2 14.4 4.7e-09 36.2 14.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CDO69179.1 - 3.2e-05 23.9 8.4 6.6e-05 22.9 8.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.11 CDO69179.1 - 0.0051 16.7 0.1 0.0096 15.8 0.1 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF3552 PF12072.8 CDO69179.1 - 0.024 14.1 2.8 0.043 13.2 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) bZIP_Maf PF03131.17 CDO69179.1 - 0.11 13.0 4.4 0.39 11.3 4.2 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor XhlA PF10779.9 CDO69179.1 - 0.13 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Hamartin PF04388.12 CDO69179.1 - 0.6 8.7 6.6 0.79 8.3 6.6 1.3 1 0 0 1 1 1 0 Hamartin protein Nucleo_P87 PF07267.11 CDO69179.1 - 2.3 7.0 5.2 3.8 6.2 5.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NTP_transferase PF00483.23 CDO69180.1 - 2e-42 145.5 0.0 3.6e-42 144.7 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CDO69180.1 - 3e-06 27.7 0.3 7.6e-06 26.4 0.3 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 CDO69180.1 - 0.00024 21.0 0.1 0.00045 20.1 0.1 1.5 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase CK2S PF15011.6 CDO69180.1 - 0.0019 18.1 0.0 0.0047 16.8 0.0 1.6 2 0 0 2 2 2 1 Casein Kinase 2 substrate IspD PF01128.19 CDO69180.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ZapB PF06005.12 CDO69180.1 - 0.15 12.5 0.6 0.3 11.5 0.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Gti1_Pac2 PF09729.9 CDO69181.1 - 2.6e-20 73.3 0.1 2.6e-18 66.8 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family GLTP PF08718.11 CDO69182.1 - 5.5e-35 120.8 0.2 7.5e-35 120.4 0.2 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Streptin-Immun PF11083.8 CDO69182.1 - 0.13 12.7 0.1 1.1 9.8 0.0 2.1 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein GAF_2 PF13185.6 CDO69183.1 - 0.00017 21.9 0.0 0.00026 21.3 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CDO69183.1 - 0.0053 17.4 0.0 0.0064 17.1 0.0 1.3 1 1 0 1 1 1 1 GAF domain tRNA-synt_1e PF01406.19 CDO69184.1 - 3.4e-127 424.0 0.1 3.4e-127 424.0 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CDO69184.1 - 7.7e-07 28.2 0.5 0.00014 20.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 CDO69184.1 - 6.5e-06 26.5 0.5 1.9e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 DALR domain tRNA-synt_1 PF00133.22 CDO69184.1 - 5.3e-05 21.7 0.0 0.00052 18.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) 2H-phosphodiest PF08975.10 CDO69184.1 - 0.084 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) ATG16 PF08614.11 CDO69186.1 - 0.00098 19.4 114.0 0.5 10.6 20.9 6.5 1 1 5 6 6 6 5 Autophagy protein 16 (ATG16) SHE3 PF17078.5 CDO69186.1 - 0.0039 16.9 14.1 0.0039 16.9 14.1 5.5 3 2 2 5 5 5 2 SWI5-dependent HO expression protein 3 Pox_A_type_inc PF04508.12 CDO69186.1 - 0.15 12.0 16.2 1.9 8.5 0.0 6.9 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat zf-CCHC_4 PF14392.6 CDO69186.1 - 0.33 10.7 4.5 6.7 6.5 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle Shugoshin_N PF07558.11 CDO69186.1 - 1.3 9.0 9.1 0.47 10.4 2.8 3.7 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region CLIP1_ZNF PF16641.5 CDO69186.1 - 1.5 8.8 15.3 1.6 8.7 4.9 2.3 2 0 0 2 2 2 0 CLIP1 zinc knuckle Fez1 PF06818.15 CDO69186.1 - 5.9 7.3 97.0 0.061 13.8 9.4 6.9 1 1 3 5 5 5 0 Fez1 Spc7 PF08317.11 CDO69186.1 - 9.1 5.1 109.9 0.13 11.1 10.4 6.2 1 1 6 7 7 7 0 Spc7 kinetochore protein CAP_GLY PF01302.25 CDO69187.1 - 2.3e-08 33.9 0.9 3.3e-08 33.4 0.9 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ribosomal_L34 PF00468.17 CDO69188.1 - 9.7e-19 67.1 9.5 1.5e-18 66.5 9.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 U1snRNP70_N PF12220.8 CDO69188.1 - 0.093 13.4 2.9 0.31 11.7 2.9 1.8 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CLASP_N PF12348.8 CDO69189.1 - 1e-27 97.2 0.0 1.5e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal Pro_racemase PF05544.11 CDO69190.1 - 6.9e-28 97.6 0.0 1.2e-27 96.9 0.0 1.4 1 1 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.16 CDO69190.1 - 0.1 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein RVT_1 PF00078.27 CDO69191.1 - 1.6e-08 34.4 0.0 5.3e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDO69191.1 - 6.8e-08 32.3 0.5 2.3e-07 30.6 0.5 1.9 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Globin PF00042.22 CDO69191.1 - 0.13 12.9 0.0 0.41 11.2 0.0 1.8 1 0 0 1 1 1 0 Globin eIF-3c_N PF05470.12 CDO69193.1 - 1.4e-182 608.2 24.6 1.4e-182 608.2 24.6 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CDO69193.1 - 1.1e-15 58.1 0.1 4.2e-14 52.9 0.0 2.9 2 0 0 2 2 2 1 PCI domain Inhibitor_I10 PF12559.8 CDO69193.1 - 0.0014 18.9 3.1 0.54 10.5 0.2 3.5 2 1 1 3 3 3 2 Serine endopeptidase inhibitors DUF2408 PF10303.9 CDO69193.1 - 0.97 10.0 11.9 2.4 8.8 4.0 4.0 3 2 0 3 3 3 0 Protein of unknown function (DUF2408) AAA_11 PF13086.6 CDO69193.1 - 8.6 6.1 15.6 0.12 12.1 5.7 2.7 3 0 0 3 3 3 0 AAA domain Hexapep PF00132.24 CDO69194.1 - 1.9e-07 30.5 0.2 0.02 14.6 1.6 3.5 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 CDO69194.1 - 0.026 12.7 0.0 0.036 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 CDO69194.1 - 0.084 12.6 2.1 0.16 11.8 1.3 1.9 1 1 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 CDO69195.1 - 5.6e-68 229.2 0.0 7.7e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69195.1 - 6.8e-50 169.8 0.0 9.6e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO69195.1 - 1e-05 25.0 0.0 2.2e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDO69195.1 - 8.9e-05 21.4 0.0 0.00017 20.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO69195.1 - 0.0007 19.6 0.0 0.24 11.3 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO69195.1 - 0.0081 15.1 0.0 0.033 13.2 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 CDO69195.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CDO69195.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APS_kinase PF01583.20 CDO69196.1 - 9.8e-63 210.8 0.5 3.3e-27 95.3 0.0 3.1 2 1 1 3 3 3 3 Adenylylsulphate kinase AAA_33 PF13671.6 CDO69196.1 - 4.8e-05 23.6 0.0 0.00012 22.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CDO69196.1 - 0.0022 18.5 0.0 0.0035 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDO69196.1 - 0.035 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 CDO69196.1 - 0.037 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Peptidase_C15 PF01470.17 CDO69197.1 - 8.8e-08 32.6 0.1 0.048 13.8 0.0 3.5 3 1 1 4 4 4 3 Pyroglutamyl peptidase MgsA_C PF12002.8 CDO69198.1 - 7.6e-54 182.1 0.0 1.3e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CDO69198.1 - 1.3e-15 57.4 0.0 3.7e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 CDO69198.1 - 2.2e-15 57.2 0.0 6.7e-15 55.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDO69198.1 - 2.3e-15 56.7 0.0 4e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CDO69198.1 - 3.7e-08 33.5 0.1 3.7e-07 30.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDO69198.1 - 5.9e-08 33.3 2.4 0.00038 20.9 0.1 3.1 2 1 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 CDO69198.1 - 1.5e-05 24.7 0.0 0.0018 18.0 0.0 2.3 1 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CDO69198.1 - 1.7e-05 24.3 0.1 0.026 13.9 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CDO69198.1 - 3.3e-05 24.2 0.2 0.0017 18.7 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 CDO69198.1 - 4.4e-05 24.0 0.0 9.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDO69198.1 - 5.7e-05 23.2 0.0 0.00015 21.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 CDO69198.1 - 0.00015 22.1 0.0 0.00068 19.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDO69198.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 CDO69198.1 - 0.0032 17.6 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.22 CDO69198.1 - 0.0035 17.7 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 CDO69198.1 - 0.0048 16.8 0.1 1.1 9.1 0.0 2.3 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 CDO69198.1 - 0.007 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain ResIII PF04851.15 CDO69198.1 - 0.012 15.6 0.0 1.6 8.7 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_2 PF07724.14 CDO69198.1 - 0.016 15.3 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.17 CDO69198.1 - 0.021 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 CDO69198.1 - 0.021 15.3 0.0 0.066 13.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 CDO69198.1 - 0.025 13.8 0.0 0.96 8.6 0.0 2.2 1 1 1 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 CDO69198.1 - 0.043 13.5 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CDO69198.1 - 0.061 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 CDO69198.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CDO69198.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 CDO69198.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase DNA_pol3_delta2 PF13177.6 CDO69198.1 - 0.14 11.9 0.0 4.5 7.0 0.0 2.2 1 1 1 2 2 2 0 DNA polymerase III, delta subunit AAA_3 PF07726.11 CDO69198.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pex14_N PF04695.13 CDO69198.1 - 2.2 8.9 10.2 4 8.1 2.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pre-SET PF05033.16 CDO69199.1 - 1.3e-19 70.8 3.0 1.3e-19 70.8 3.0 1.9 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.28 CDO69199.1 - 4.2e-15 56.5 1.2 4.2e-15 56.5 1.2 2.2 2 1 0 2 2 2 1 SET domain Glyco_hydro_61 PF03443.14 CDO69200.1 - 4.7e-54 183.5 1.0 5.5e-54 183.2 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1168 PF06658.12 CDO69201.1 - 1.2e-38 132.0 21.4 2e-38 131.3 21.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) CMS1 PF14617.6 CDO69201.1 - 0.37 10.1 9.8 0.54 9.5 9.8 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Peptidase_S49_N PF08496.10 CDO69201.1 - 2.8 8.0 7.5 4.4 7.3 7.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SAPS PF04499.15 CDO69201.1 - 6.9 5.3 6.3 9 5.0 6.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 CDO69201.1 - 8.5 6.4 5.4 10 6.1 5.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_S8e PF01201.22 CDO69202.1 - 5.9e-49 165.8 0.6 1.1e-48 164.9 0.6 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e Neur_chan_memb PF02932.16 CDO69202.1 - 0.16 12.0 1.2 0.23 11.5 1.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Yip1 PF04893.17 CDO69203.1 - 1.7e-08 34.3 12.1 2.7e-08 33.7 12.1 1.3 1 0 0 1 1 1 1 Yip1 domain FSA_C PF10479.9 CDO69204.1 - 0.19 9.8 1.3 0.36 8.9 1.3 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF1746 PF08508.10 CDO69205.1 - 0.00056 20.2 0.6 0.00095 19.5 0.6 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) COG4 PF08318.12 CDO69206.1 - 0.45 9.5 2.1 0.36 9.9 0.3 1.7 2 0 0 2 2 2 0 COG4 transport protein Peptidase_C14 PF00656.22 CDO69207.1 - 8.6e-16 58.6 0.0 1.2e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain APG6 PF04111.12 CDO69208.1 - 1.5e-71 240.0 0.0 2.2e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CDO69208.1 - 4.7e-30 104.8 23.1 4.7e-30 104.8 23.1 1.5 2 0 0 2 2 2 1 Apg6 coiled-coil region Talin_middle PF09141.10 CDO69208.1 - 0.14 12.2 2.1 0.32 11.0 2.1 1.6 1 0 0 1 1 1 0 Talin, middle domain V_ATPase_I PF01496.19 CDO69208.1 - 0.87 7.4 5.0 1.2 7.0 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 CDO69208.1 - 0.88 8.0 3.9 1.4 7.3 3.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 CDO69208.1 - 0.99 9.5 12.8 1.8 8.7 12.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 CDO69208.1 - 6.3 5.3 7.7 8.4 4.9 7.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GCS PF03074.16 CDO69209.1 - 4.2e-133 444.2 0.0 1.9e-121 405.9 0.0 2.1 1 1 1 2 2 2 2 Glutamate-cysteine ligase DUF1793 PF08760.11 CDO69210.1 - 1.2e-40 139.7 0.8 2.6e-40 138.6 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 CDO69210.1 - 3.4e-39 135.0 0.4 3.4e-39 135.0 0.4 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 CDO69210.1 - 7.2e-21 74.6 0.2 6.4e-16 58.5 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4965) Herpes_gE PF02480.16 CDO69210.1 - 0.17 10.6 0.1 0.79 8.4 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.10 CDO69210.1 - 0.17 11.3 1.6 0.42 10.1 1.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PEP-CTERM PF07589.11 CDO69210.1 - 7.6 6.8 6.8 22 5.3 6.8 1.9 1 0 0 1 1 1 0 PEP-CTERM motif VanZ PF04892.12 CDO69211.1 - 9.3e-05 23.1 2.3 0.00018 22.2 2.3 1.5 1 1 0 1 1 1 1 VanZ like family Phage_holin_3_3 PF16083.5 CDO69211.1 - 0.072 13.2 0.4 0.072 13.2 0.4 1.5 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III Acyl_transf_3 PF01757.22 CDO69211.1 - 0.094 11.8 6.4 0.13 11.3 6.4 1.2 1 0 0 1 1 1 0 Acyltransferase family AA_permease_2 PF13520.6 CDO69211.1 - 0.12 11.2 4.4 0.15 10.9 4.4 1.1 1 0 0 1 1 1 0 Amino acid permease LapA_dom PF06305.11 CDO69211.1 - 0.97 9.3 7.8 1.4 8.8 0.5 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SBD_N PF07005.11 CDO69212.1 - 0.012 15.4 1.0 0.028 14.2 0.4 1.9 1 1 0 1 1 1 0 Sugar-binding N-terminal domain TolA_bind_tri PF16331.5 CDO69212.1 - 0.075 13.1 0.3 4.7 7.3 0.2 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation Pox_A_type_inc PF04508.12 CDO69212.1 - 0.18 11.7 0.8 3.3 7.7 0.1 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Cob_adeno_trans PF01923.18 CDO69212.1 - 3.2 7.9 5.1 23 5.1 0.2 3.0 2 1 2 4 4 4 0 Cobalamin adenosyltransferase PALP PF00291.25 CDO69213.1 - 1.7e-71 241.0 0.1 2.1e-71 240.7 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.21 CDO69214.1 - 9.4e-64 214.1 0.5 9.4e-61 204.3 0.5 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDO69214.1 - 1.5e-11 44.6 0.1 2.8e-11 43.7 0.1 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CDO69214.1 - 3.9e-09 36.3 0.0 4.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CDO69214.1 - 5e-08 32.5 0.3 1.8e-07 30.6 0.2 1.9 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 CDO69214.1 - 4e-07 29.6 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDO69214.1 - 2e-06 27.3 0.0 2.8e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDO69214.1 - 0.0013 18.8 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Macro_2 PF14519.6 CDO69215.1 - 0.07 12.4 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Macro-like domain LRR_8 PF13855.6 CDO69216.1 - 1.1e-11 44.4 17.3 5.1e-09 35.8 7.3 3.7 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 CDO69216.1 - 3.3e-11 43.2 16.4 1.4e-05 25.4 2.2 4.7 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDO69216.1 - 0.033 13.7 0.2 0.094 12.2 0.1 1.7 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 CDO69216.1 - 0.24 11.5 14.5 3.8 7.8 1.1 5.3 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CDO69216.1 - 0.61 10.8 14.6 9.9 7.2 0.1 6.0 5 1 0 5 5 5 0 Leucine Rich Repeat UBA PF00627.31 CDO69217.1 - 1.8e-29 101.2 5.8 2.6e-14 52.8 0.8 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 CDO69217.1 - 5.9e-22 77.2 1.5 9.6e-22 76.5 1.5 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 CDO69217.1 - 5.3e-19 67.7 10.5 5.3e-19 67.7 10.5 2.2 2 0 0 2 2 1 1 XPC-binding domain Rad60-SLD PF11976.8 CDO69217.1 - 1.7e-08 34.1 1.7 3.4e-08 33.2 1.5 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CDO69217.1 - 0.00069 19.7 0.1 0.0017 18.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDO69217.1 - 0.0017 18.9 0.0 0.0036 17.9 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UBA_3 PF09288.10 CDO69217.1 - 0.0027 17.5 0.0 0.53 10.1 0.0 2.4 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Ubiquitin_2 PF14560.6 CDO69217.1 - 0.0038 17.7 0.3 0.007 16.8 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain WIYLD PF10440.9 CDO69217.1 - 0.0063 16.3 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-binding WIYLD domain CUE PF02845.16 CDO69217.1 - 0.015 15.0 0.0 0.13 12.0 0.0 2.5 3 0 0 3 3 3 0 CUE domain Ubiquitin_4 PF18036.1 CDO69217.1 - 0.024 14.6 0.7 0.066 13.3 0.5 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CDO69217.1 - 0.038 14.3 0.2 0.072 13.4 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Pex14_N PF04695.13 CDO69217.1 - 0.69 10.5 23.5 0.4 11.3 9.3 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HNH_2 PF13391.6 CDO69218.1 - 1.8e-09 37.6 0.0 4.2e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease IGF2_C PF08365.11 CDO69219.1 - 0.0068 16.4 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Insulin-like growth factor II E-peptide TfoX_N PF04993.13 CDO69219.1 - 0.083 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 TfoX N-terminal domain IMS PF00817.20 CDO69221.1 - 4.7e-46 156.5 0.0 1.3e-45 155.1 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CDO69221.1 - 6.2e-11 43.0 1.4 1.4e-10 41.9 0.1 2.3 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CDO69221.1 - 5e-07 29.7 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif RNF220 PF15926.5 CDO69221.1 - 0.012 15.3 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 RelB_transactiv PF16181.5 CDO69221.1 - 0.022 15.0 0.4 0.047 13.9 0.4 1.5 1 0 0 1 1 1 0 RelB transactivation domain zf-U1 PF06220.12 CDO69222.1 - 4.1e-12 45.6 2.0 6.4e-12 45.0 2.0 1.3 1 0 0 1 1 1 1 U1 zinc finger DUF1877 PF08974.10 CDO69223.1 - 0.027 14.6 0.0 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) UPF0020 PF01170.18 CDO69224.1 - 0.007 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CDO69224.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 1 0 1 1 1 0 DNA methylase 2OG-FeII_Oxy_2 PF13532.6 CDO69225.1 - 3.2e-17 63.4 0.0 5.8e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_79C PF16862.5 CDO69226.1 - 1.1e-13 51.9 0.6 2.6e-13 50.7 0.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Sdh_cyt PF01127.22 CDO69227.1 - 1.9e-25 89.2 1.0 2.4e-25 88.9 1.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ATP-synt_DE_N PF02823.16 CDO69228.1 - 3.5e-17 62.1 0.1 9e-17 60.8 0.1 1.7 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cob_adeno_trans PF01923.18 CDO69228.1 - 0.0014 18.8 0.4 0.0014 18.8 0.4 2.7 2 1 0 2 2 2 1 Cobalamin adenosyltransferase PhaP_Bmeg PF09602.10 CDO69228.1 - 1.1 9.1 8.0 1.1 9.1 0.2 3.4 3 1 1 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Pyrid_ox_like PF16242.5 CDO69229.1 - 6e-31 107.1 0.1 8.4e-31 106.6 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 CDO69229.1 - 7.8e-11 42.0 0.0 2.5e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase HSP9_HSP12 PF04119.12 CDO69230.1 - 9.1e-22 77.2 11.9 1.5e-21 76.6 9.5 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 Lipase_3 PF01764.25 CDO69232.1 - 1.1e-24 86.9 0.1 1.5e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 CDO69232.1 - 0.008 15.7 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 CDO69232.1 - 0.013 16.1 0.1 0.023 15.3 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Aminotran_3 PF00202.21 CDO69233.1 - 6.8e-119 397.1 0.0 8.4e-119 396.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CDO69233.1 - 4.9e-07 29.2 0.0 6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CDO69233.1 - 0.0041 16.4 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase zf-ANAPC11 PF12861.7 CDO69233.1 - 0.1 12.7 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Reprolysin_4 PF13583.6 CDO69234.1 - 0.1 12.2 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like zf-RING_2 PF13639.6 CDO69235.1 - 7.9e-13 48.5 5.8 1.3e-12 47.8 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDO69235.1 - 1.9e-07 30.7 5.7 3e-07 30.1 2.5 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDO69235.1 - 8.5e-07 28.7 4.4 1.4e-06 28.0 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDO69235.1 - 2.3e-06 27.6 1.7 4.4e-06 26.7 1.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CDO69235.1 - 2.7e-06 27.1 3.4 4.6e-06 26.3 3.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 CDO69235.1 - 3.1e-05 23.7 2.5 5.3e-05 23.0 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDO69235.1 - 3.6e-05 24.0 6.2 0.00011 22.4 6.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDO69235.1 - 0.00013 21.8 1.5 0.00022 21.0 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO69235.1 - 0.00034 20.6 2.6 0.037 14.1 1.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDO69235.1 - 0.00034 20.5 2.2 0.00055 19.8 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDO69235.1 - 0.0013 18.5 6.6 0.013 15.4 7.3 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CDO69235.1 - 0.0069 16.5 2.5 0.017 15.3 2.5 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 CDO69235.1 - 0.013 15.6 3.4 0.024 14.7 3.4 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 CDO69235.1 - 0.023 14.6 4.9 0.24 11.4 1.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 CDO69235.1 - 0.65 9.7 2.5 1.3 8.7 2.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type UBZ_FAAP20 PF15750.5 CDO69235.1 - 4.5 7.3 6.8 7.3 6.6 0.5 2.8 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Aminotran_3 PF00202.21 CDO69237.1 - 4e-39 134.4 0.0 4.2e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CDO69237.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase HSP9_HSP12 PF04119.12 CDO69238.1 - 1.3e-24 86.3 5.4 1.3e-24 86.3 5.4 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 F-box-like PF12937.7 CDO69240.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like Aa_trans PF01490.18 CDO69241.1 - 2.3e-64 217.6 24.1 1.2e-63 215.3 24.1 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CDO69241.1 - 0.0016 17.6 10.0 0.0016 17.6 10.0 2.6 2 2 0 2 2 2 1 Tryptophan/tyrosine permease family GHMP_kinases_N PF00288.26 CDO69242.1 - 1.7e-14 53.8 2.1 7.6e-14 51.7 2.1 2.2 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CDO69242.1 - 0.00062 20.1 0.0 0.0018 18.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DUF1727 PF08353.10 CDO69242.1 - 0.06 13.3 0.1 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) ABC_membrane PF00664.23 CDO69243.1 - 3.4e-104 348.4 20.8 2.5e-54 184.8 8.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDO69243.1 - 7.5e-71 237.0 0.0 4.2e-34 118.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDO69243.1 - 2.5e-15 56.5 0.6 6.5e-05 22.5 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDO69243.1 - 4.2e-07 30.5 2.2 0.002 18.6 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CDO69243.1 - 4.7e-07 29.0 0.6 0.002 17.0 0.1 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 CDO69243.1 - 8.1e-07 28.7 0.7 0.0096 15.7 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CDO69243.1 - 1.7e-06 28.3 1.0 0.045 14.0 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 CDO69243.1 - 2.6e-06 27.5 0.1 0.21 11.3 0.1 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDO69243.1 - 2e-05 24.5 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CDO69243.1 - 2.5e-05 24.2 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 CDO69243.1 - 4.7e-05 22.8 0.0 0.056 12.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 CDO69243.1 - 7.7e-05 22.5 0.9 0.7 9.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CDO69243.1 - 0.00086 18.9 1.7 0.41 10.2 0.2 3.0 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 CDO69243.1 - 0.001 18.3 0.0 0.77 8.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA PF00004.29 CDO69243.1 - 0.0017 18.8 1.2 0.58 10.6 0.1 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CDO69243.1 - 0.0017 18.9 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CDO69243.1 - 0.0019 18.2 0.2 1.7 8.6 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDO69243.1 - 0.0027 18.3 0.0 3 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDO69243.1 - 0.0028 17.8 0.0 4.7 7.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 CDO69243.1 - 0.0033 17.0 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 CDO69243.1 - 0.0048 17.1 3.1 4.4 7.6 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit PRK PF00485.18 CDO69243.1 - 0.0065 16.2 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 CDO69243.1 - 0.0089 16.3 1.1 2.7 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 CDO69243.1 - 0.039 14.4 0.1 19 5.7 0.0 3.2 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 CDO69243.1 - 0.041 13.5 0.1 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 CDO69243.1 - 0.042 13.9 0.1 14 5.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 CDO69243.1 - 0.051 13.3 0.1 7.2 6.3 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 CDO69243.1 - 0.063 13.2 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 CDO69243.1 - 0.068 12.3 0.1 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 CDO69243.1 - 0.078 13.4 0.0 7.2 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 CDO69243.1 - 0.11 11.7 0.0 4.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CDO69243.1 - 0.13 12.0 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CDO69243.1 - 0.16 11.9 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain DUF87 PF01935.17 CDO69243.1 - 1.1 9.3 3.2 9.6 6.2 0.1 3.0 4 0 0 4 4 2 0 Helicase HerA, central domain Rsd_AlgQ PF04353.13 CDO69244.1 - 0.047 13.7 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Phage_capsid PF05065.13 CDO69244.1 - 0.1 11.9 0.1 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Phage capsid family UDPGT PF00201.18 CDO69247.1 - 7.9e-16 57.9 0.0 1.1e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO69247.1 - 0.00047 20.2 0.0 0.00083 19.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF1080 PF06439.11 CDO69248.1 - 0.051 13.7 0.0 0.077 13.1 0.0 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) Pro-kuma_activ PF09286.11 CDO69249.1 - 5.7e-37 127.2 0.0 2.4e-36 125.1 0.0 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO69249.1 - 1.1e-07 31.4 1.7 1.6e-07 30.9 1.7 1.3 1 0 0 1 1 1 1 Subtilase family Lipase_3 PF01764.25 CDO69250.1 - 1e-26 93.5 0.1 1.4e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 CDO69250.1 - 0.003 17.1 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.8 CDO69250.1 - 0.0034 17.0 0.0 0.037 13.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CDO69250.1 - 0.012 16.2 0.2 0.029 15.0 0.1 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Cutinase PF01083.22 CDO69250.1 - 0.02 14.8 0.0 0.029 14.3 0.0 1.4 1 1 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.13 CDO69250.1 - 0.042 13.7 0.0 0.13 12.1 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF21 PF01595.20 CDO69251.1 - 1.6e-24 86.5 0.8 2.3e-24 86.1 0.8 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain DUF4106 PF13388.6 CDO69252.1 - 2.4 7.3 6.4 3.1 6.9 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Pkinase PF00069.25 CDO69253.1 - 1.1e-62 211.9 0.0 1.3e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69253.1 - 9.4e-30 103.7 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO69253.1 - 2.9e-07 30.1 0.0 5.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CDO69253.1 - 0.0058 16.3 0.0 0.56 9.8 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDO69253.1 - 0.037 13.4 0.1 0.08 12.3 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO69253.1 - 0.053 13.4 0.2 0.24 11.3 0.1 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family ACT PF01842.25 CDO69254.1 - 3.7e-13 49.0 0.1 6e-13 48.3 0.1 1.3 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 CDO69254.1 - 6.1e-07 29.2 0.1 9.2e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 ACT domain COG5 PF10392.9 CDO69255.1 - 2.8e-23 82.5 0.0 2.1e-22 79.7 0.0 2.4 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF4106 PF13388.6 CDO69257.1 - 5.1 6.2 5.6 7.2 5.7 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Zn_clus PF00172.18 CDO69258.1 - 1.5e-05 25.0 9.1 2.9e-05 24.1 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GshA PF08886.11 CDO69258.1 - 0.24 9.9 0.0 0.33 9.5 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase TPT PF03151.16 CDO69259.1 - 2.9e-16 59.7 19.3 1.1e-15 57.8 11.6 2.0 1 1 1 2 2 2 2 Triose-phosphate Transporter family PUNUT PF16913.5 CDO69259.1 - 0.0053 16.0 18.0 0.016 14.4 17.9 1.8 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 CDO69259.1 - 0.0095 16.1 39.8 0.022 14.9 13.2 3.0 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CDO69259.1 - 0.019 14.2 18.0 0.034 13.3 18.0 1.5 1 1 0 1 1 1 0 UAA transporter family Peptidase_C12 PF01088.21 CDO69260.1 - 5.1e-56 189.7 0.0 8.1e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CDO69260.1 - 1e-16 60.5 0.4 2.7e-16 59.2 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases AA_permease PF00324.21 CDO69261.1 - 3.4e-112 375.5 44.7 4.1e-112 375.2 44.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CDO69261.1 - 5.1e-32 111.2 51.4 6.6e-32 110.9 51.4 1.1 1 0 0 1 1 1 1 Amino acid permease IFP_35_N PF07334.13 CDO69262.1 - 0.17 12.0 1.2 0.34 11.0 1.2 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FAD_binding_2 PF00890.24 CDO69263.1 - 7e-91 305.4 0.1 9.2e-91 305.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 CDO69263.1 - 2.6e-24 85.2 0.0 9.7e-24 83.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 CDO69263.1 - 9.4e-13 48.5 0.3 4.5e-12 46.2 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDO69263.1 - 1.2e-10 41.1 0.1 1.6e-08 34.2 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO69263.1 - 2.7e-10 40.3 0.3 2e-09 37.5 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CDO69263.1 - 3.4e-09 36.6 0.1 5.5e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDO69263.1 - 1.1e-06 28.2 0.1 1.9e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CDO69263.1 - 2.6e-06 26.8 1.3 8.1e-05 21.9 0.5 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 CDO69263.1 - 4.5e-06 25.6 3.0 8.3e-05 21.5 0.3 2.9 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 CDO69263.1 - 2e-05 24.1 0.2 0.0027 17.1 0.2 3.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 CDO69263.1 - 9e-05 21.8 1.2 0.024 13.9 0.6 2.4 2 0 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.21 CDO69263.1 - 0.00014 21.2 0.5 0.00025 20.4 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 CDO69263.1 - 0.00038 19.8 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CDO69263.1 - 0.0021 17.2 0.1 0.013 14.5 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 CDO69263.1 - 0.0023 17.9 0.2 0.87 9.6 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CDO69263.1 - 0.0073 16.9 0.4 0.039 14.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CDO69263.1 - 0.027 14.9 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 CDO69263.1 - 0.15 11.9 0.3 0.5 10.2 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 CDO69263.1 - 0.19 10.4 0.1 0.35 9.6 0.1 1.4 2 0 0 2 2 2 0 MCRA family Pro-kuma_activ PF09286.11 CDO69264.1 - 2.2e-37 128.5 0.1 2.6e-36 125.0 0.0 2.4 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO69264.1 - 0.00012 21.4 1.6 0.00023 20.6 1.6 1.4 1 0 0 1 1 1 1 Subtilase family Ish1 PF10281.9 CDO69264.1 - 0.089 13.1 0.0 0.35 11.2 0.0 2.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Mitofilin PF09731.9 CDO69265.1 - 3.7e-06 26.1 10.0 3.9e-06 26.0 10.0 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein AIF-MLS PF14962.6 CDO69265.1 - 0.0028 17.6 5.2 0.0028 17.6 5.2 1.9 2 0 0 2 2 2 1 Mitochondria Localisation Sequence Remorin_C PF03763.13 CDO69265.1 - 0.0066 16.3 10.7 0.0066 16.3 10.7 2.8 1 1 1 2 2 2 1 Remorin, C-terminal region Apolipoprotein PF01442.18 CDO69265.1 - 0.014 15.3 14.5 0.014 15.3 14.5 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain HemX PF04375.14 CDO69265.1 - 0.035 13.4 8.2 0.049 12.9 7.7 1.5 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase KELK PF15796.5 CDO69265.1 - 0.43 11.1 6.8 0.51 10.8 4.2 2.2 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF883 PF05957.13 CDO69265.1 - 5.6 7.6 22.3 4.7 7.9 16.0 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 CDO69265.1 - 6.1 6.9 14.5 0.29 11.1 6.6 2.4 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MRP_L53 PF10780.9 CDO69268.1 - 0.034 14.3 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 His_Phos_2 PF00328.22 CDO69269.1 - 0.0034 16.8 0.5 0.68 9.2 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) adh_short PF00106.25 CDO69271.1 - 2e-37 128.6 0.0 2.5e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69271.1 - 1.2e-28 100.3 0.0 1.8e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO69271.1 - 1.4e-06 28.3 0.0 2.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CDO69271.1 - 0.00015 21.2 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 CDO69271.1 - 0.00026 20.9 0.1 0.00045 20.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CDO69271.1 - 0.0039 16.7 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 CDO69271.1 - 0.075 12.8 1.6 0.15 11.8 1.6 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Iwr1 PF08574.10 CDO69272.1 - 4.5e-14 53.2 10.4 4.5e-14 53.2 10.4 2.3 3 0 0 3 3 3 1 Transcription factor Iwr1 TFIIA PF03153.13 CDO69272.1 - 0.0059 16.7 9.2 0.0091 16.0 9.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Flexi_CP PF00286.20 CDO69272.1 - 0.017 15.1 0.1 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 Viral coat protein DUF5009 PF16401.5 CDO69273.1 - 0.036 13.5 0.0 0.055 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5009) F-box-like PF12937.7 CDO69274.1 - 4.4e-14 52.1 1.1 2.3e-13 49.8 1.0 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 CDO69274.1 - 0.053 13.4 4.4 0.68 9.9 2.1 3.6 2 1 0 2 2 2 0 F-box domain MFS_1 PF07690.16 CDO69278.1 - 1.3e-30 106.6 15.5 8.7e-19 67.6 2.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO69278.1 - 9.4e-05 21.4 30.0 0.00012 21.1 6.2 3.7 3 1 1 4 4 4 3 Sugar (and other) transporter Retinal PF15449.6 CDO69278.1 - 1.9 6.2 12.7 3 5.5 12.7 1.3 1 0 0 1 1 1 0 Retinal protein PHY PF00360.20 CDO69279.1 - 1.1e-24 86.7 0.0 2e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 CDO69279.1 - 5.9e-21 75.1 0.0 1.3e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CDO69279.1 - 3.6e-19 69.0 0.1 1.4e-18 67.0 0.1 2.0 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 CDO69279.1 - 1.1e-11 44.6 1.2 3.3e-11 43.0 1.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 CDO69279.1 - 1.2e-09 38.9 1.6 2.8e-08 34.5 0.1 3.8 3 1 0 3 3 3 1 GAF domain PAS_2 PF08446.11 CDO69279.1 - 1.4e-07 32.2 0.1 7.7e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold OKR_DC_1_N PF03709.15 CDO69279.1 - 2.1e-05 24.7 0.0 6.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain BTB PF00651.31 CDO69282.1 - 0.00024 21.3 0.0 0.0015 18.8 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain TF_Zn_Ribbon PF08271.12 CDO69282.1 - 0.13 11.8 1.5 0.34 10.4 0.0 2.4 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 CDO69282.1 - 0.26 11.1 1.6 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CDO69282.1 - 0.56 9.7 3.0 0.48 9.9 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain adh_short PF00106.25 CDO69284.1 - 3.5e-35 121.2 1.4 5.2e-35 120.7 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69284.1 - 7.8e-35 120.5 3.6 1.3e-34 119.7 3.6 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO69284.1 - 1.9e-05 24.6 4.1 0.00082 19.3 0.7 2.8 3 0 0 3 3 3 2 KR domain Epimerase PF01370.21 CDO69284.1 - 0.00022 20.7 0.6 0.0027 17.2 0.6 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDO69284.1 - 0.042 13.0 0.1 0.077 12.1 0.1 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 CDO69284.1 - 0.087 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Spt20 PF12090.8 CDO69285.1 - 0.22 11.1 7.0 0.29 10.7 7.0 1.2 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 CDO69285.1 - 8.8 4.5 10.7 9.2 4.4 10.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ODC_AZ PF02100.17 CDO69286.1 - 5.8e-14 52.0 0.0 7.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme PIF1 PF05970.14 CDO69287.1 - 8.8e-73 245.6 0.0 1.1e-72 245.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CDO69287.1 - 6e-12 45.7 0.0 9.6e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDO69287.1 - 1e-06 28.3 0.0 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CDO69287.1 - 0.00046 20.5 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDO69287.1 - 0.0015 18.9 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF2791 PF10923.8 CDO69287.1 - 0.022 13.6 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Viral_helicase1 PF01443.18 CDO69287.1 - 0.029 14.1 0.6 5.4 6.7 0.1 2.9 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CDO69287.1 - 0.031 14.1 0.1 0.066 13.1 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain NACHT PF05729.12 CDO69287.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Herpes_Helicase PF02689.14 CDO69287.1 - 0.092 10.7 0.1 0.98 7.3 0.0 2.0 2 0 0 2 2 2 0 Helicase SNase PF00565.17 CDO69288.1 - 1.4e-57 192.8 0.1 1.2e-20 74.0 0.2 6.1 6 0 0 6 6 6 6 Staphylococcal nuclease homologue TUDOR PF00567.24 CDO69288.1 - 5.1e-21 75.0 0.0 1.3e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 CDO69288.1 - 0.047 14.2 0.1 0.26 11.8 0.0 2.4 2 0 0 2 2 2 0 Agenet domain Ribosomal_S6 PF01250.17 CDO69289.1 - 7.2e-23 80.7 0.0 9e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Hydrolase_like PF13242.6 CDO69290.1 - 1.2e-10 41.3 0.0 2.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 CDO69290.1 - 1.2e-09 38.5 0.0 5.4e-09 36.4 0.0 2.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDO69290.1 - 2e-07 31.6 0.0 5.1e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRM_2 PF04059.12 CDO69291.1 - 3.3e-31 107.3 1.1 6.1e-31 106.5 1.1 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 CDO69291.1 - 1e-12 47.7 0.0 0.00075 19.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 CDO69291.1 - 1.2e-06 28.6 0.0 0.0065 16.7 0.1 2.7 2 0 0 2 2 2 2 BRCA1-associated protein 2 RRM_5 PF13893.6 CDO69291.1 - 0.14 11.8 0.0 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNF2_N PF00176.23 CDO69292.1 - 9.1e-67 225.2 0.0 1.5e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 CDO69292.1 - 1.6e-21 76.0 0.0 3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.18 CDO69292.1 - 3.8e-16 59.7 0.0 1.3e-15 58.0 0.0 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.31 CDO69292.1 - 1.1e-11 45.0 0.0 2.9e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 CDO69292.1 - 1.4e-08 34.4 5.4 2.9e-08 33.4 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 CDO69292.1 - 3.9e-08 33.5 0.0 8.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CDO69292.1 - 2.3e-07 30.5 4.7 4.5e-07 29.6 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO69292.1 - 3.7e-07 30.4 4.9 7e-07 29.5 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDO69292.1 - 1.1e-06 28.3 6.2 2e-06 27.5 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO69292.1 - 2.5e-06 27.3 3.1 4.6e-06 26.5 3.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDO69292.1 - 3.1e-06 27.1 7.6 6.5e-06 26.1 7.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDO69292.1 - 6.2e-05 23.1 6.7 0.00012 22.1 6.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CDO69292.1 - 0.00041 20.6 3.2 0.0011 19.2 3.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain DEAD PF00270.29 CDO69292.1 - 0.0014 18.5 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 CDO69292.1 - 0.0087 15.9 5.5 0.012 15.5 4.4 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 WW PF00397.26 CDO69292.1 - 0.085 13.0 0.6 0.2 11.8 0.6 1.7 1 0 0 1 1 1 0 WW domain zf-RING_11 PF17123.5 CDO69292.1 - 5.1 6.9 6.4 13 5.6 6.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger Metallophos PF00149.28 CDO69293.1 - 2.5e-06 28.2 0.0 3.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ten1_2 PF15490.6 CDO69294.1 - 5.4e-07 29.3 0.0 7.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit UDPGP PF01704.18 CDO69295.1 - 5.1e-198 657.8 0.9 5.9e-198 657.6 0.9 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Thioredoxin_15 PF18403.1 CDO69295.1 - 0.11 12.4 0.2 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain U3_assoc_6 PF08640.11 CDO69297.1 - 3.6e-31 107.1 1.1 2.3e-28 98.1 0.5 2.4 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 CDO69297.1 - 5.3e-05 23.7 15.6 0.095 13.6 1.2 5.6 4 2 2 6 6 6 3 Tetratricopeptide repeat NRDE-2 PF08424.10 CDO69297.1 - 0.0014 17.8 1.7 0.0072 15.5 0.1 2.3 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 CDO69297.1 - 0.24 10.6 3.8 0.44 9.7 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 CDO69298.1 - 8.8e-34 117.1 0.0 8.4e-21 74.5 0.0 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69298.1 - 1.2e-18 67.3 0.0 2.8e-18 66.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Cyclin PF08613.11 CDO69299.1 - 9.6e-29 100.8 0.3 1.8e-28 99.9 0.0 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CDO69299.1 - 0.00035 20.3 0.0 0.00035 20.3 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Med3 PF11593.8 CDO69299.1 - 0.21 10.7 8.9 0.29 10.3 8.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 CDO69299.1 - 1.2 8.7 9.5 1.5 8.3 9.5 1.2 1 0 0 1 1 1 0 Spt20 family Ribosomal_L11_N PF03946.14 CDO69300.1 - 6.5e-24 83.6 0.1 1e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CDO69300.1 - 5.8e-13 49.1 0.1 1.4e-12 47.9 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein L11, RNA binding domain tRNA-synt_1 PF00133.22 CDO69301.1 - 3.5e-224 745.5 0.5 1.3e-223 743.7 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CDO69301.1 - 6.6e-27 94.3 0.0 1.4e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CDO69301.1 - 2.1e-12 46.5 0.9 3.4e-05 22.8 0.3 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CDO69301.1 - 0.021 14.2 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-C2H2_jaz PF12171.8 CDO69302.1 - 2.1e-07 31.0 0.0 3.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDO69302.1 - 7.4e-07 29.4 0.1 1.2e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 CDO69302.1 - 6.9e-05 22.8 3.0 0.00022 21.2 3.0 1.9 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 CDO69302.1 - 0.00075 19.6 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_4 PF13894.6 CDO69302.1 - 0.018 15.8 0.1 0.036 14.9 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDO69302.1 - 0.019 15.4 0.2 0.034 14.6 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Apolipoprotein PF01442.18 CDO69303.1 - 0.00046 20.1 12.3 0.00046 20.1 12.3 3.0 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain Peptidase_M41 PF01434.18 CDO69303.1 - 0.0044 16.9 8.5 1.3 8.8 0.2 4.1 4 0 0 4 4 4 2 Peptidase family M41 Gp-FAR-1 PF05823.12 CDO69303.1 - 0.0044 17.4 3.0 0.0044 17.4 3.0 4.1 2 1 2 4 4 4 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HATPase_c_3 PF13589.6 CDO69303.1 - 0.012 15.4 0.2 0.034 14.0 0.2 1.8 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5398 PF17376.2 CDO69303.1 - 0.021 15.5 0.3 0.021 15.5 0.3 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5398) MIEAP PF16026.5 CDO69303.1 - 0.03 14.5 4.6 0.091 13.0 1.6 2.4 2 0 0 2 2 2 0 Mitochondria-eating protein HATPase_c PF02518.26 CDO69303.1 - 0.065 13.7 0.2 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sep15_SelM PF08806.11 CDO69303.1 - 0.089 13.0 2.2 20 5.4 0.2 3.2 3 0 0 3 3 3 0 Sep15/SelM redox domain DUF883 PF05957.13 CDO69303.1 - 0.093 13.3 0.5 0.093 13.3 0.5 5.6 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF883) QIL1 PF15884.5 CDO69303.1 - 0.95 10.1 3.8 2.5 8.8 0.0 3.3 3 1 1 4 4 4 0 MICOS complex subunit MIC13, QIL1 Fox-1_C PF12414.8 CDO69303.1 - 0.96 9.9 4.6 2.6 8.5 4.6 1.7 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Cbl_N PF02262.16 CDO69303.1 - 1.4 9.0 4.7 7.1 6.7 0.6 3.3 2 1 1 3 3 3 0 CBL proto-oncogene N-terminal domain 1 Syntaxin-18_N PF10496.9 CDO69303.1 - 9.3 6.6 7.6 0.59 10.4 0.3 2.8 2 1 1 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus LRR_4 PF12799.7 CDO69304.1 - 5.5 7.6 8.6 2.3 8.8 0.3 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) BTB PF00651.31 CDO69305.1 - 0.018 15.3 0.0 4.7 7.5 0.0 2.8 2 1 0 2 2 2 0 BTB/POZ domain CAF1A PF12253.8 CDO69307.1 - 1.1 9.5 8.4 0.043 14.0 2.5 1.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A AAA PF00004.29 CDO69309.1 - 2.7e-06 27.8 0.1 7.6e-05 23.2 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CDO69309.1 - 0.0029 17.6 0.2 0.073 13.0 0.0 2.7 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 CDO69309.1 - 0.0032 17.9 0.0 0.013 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Metallophos PF00149.28 CDO69310.1 - 0.00011 22.7 0.1 0.00018 22.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2407_C PF13373.6 CDO69311.1 - 0.031 14.5 0.4 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 DUF2407 C-terminal domain Cid2 PF09774.9 CDO69311.1 - 0.064 13.7 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF2207 PF09972.9 CDO69311.1 - 0.13 11.0 3.3 14 4.3 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MFS_2 PF13347.6 CDO69311.1 - 0.24 9.9 9.0 1.5 7.3 0.5 2.3 2 1 0 2 2 2 0 MFS/sugar transport protein CPSase_sm_chain PF00988.22 CDO69312.1 - 1.9e-45 153.8 0.0 3e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CDO69312.1 - 4.6e-37 127.6 0.0 6.4e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDO69312.1 - 6.2e-08 32.7 0.1 2.1e-06 27.6 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 CDO69312.1 - 0.0068 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family bMG10 PF17973.1 CDO69312.1 - 0.068 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain BSD PF03909.17 CDO69313.1 - 9.1e-10 38.4 0.3 3.6e-09 36.5 0.1 2.1 2 0 0 2 2 2 1 BSD domain DUF883 PF05957.13 CDO69313.1 - 0.018 15.6 5.7 3 8.5 0.0 3.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF2267 PF10025.9 CDO69313.1 - 0.097 13.0 5.5 0.061 13.6 2.1 2.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2267) Apo-CII PF05355.11 CDO69313.1 - 0.12 12.6 0.2 0.93 9.7 0.0 2.5 3 0 0 3 3 3 0 Apolipoprotein C-II Apolipoprotein PF01442.18 CDO69313.1 - 0.43 10.4 9.8 0.53 10.1 8.0 2.2 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain V-ATPase_G_2 PF16999.5 CDO69313.1 - 7.4 7.0 13.6 8.1 6.9 10.0 2.8 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit RT_RNaseH PF17917.1 CDO69315.1 - 1.1e-36 125.3 0.0 2.1e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO69315.1 - 7.5e-32 110.6 0.0 1.2e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDO69315.1 - 2.4e-31 107.7 0.0 5.8e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDO69315.1 - 2.1e-16 59.7 0.2 5.8e-16 58.4 0.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO69315.1 - 2.3e-15 56.8 0.0 1.4e-14 54.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 CDO69315.1 - 8.4e-06 25.9 0.1 1.9e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 CDO69315.1 - 0.0012 18.7 0.1 0.0027 17.6 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CENP-Q PF13094.6 CDO69316.1 - 0.47 10.6 20.7 0.78 9.9 8.2 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RP-C_C PF11800.8 CDO69316.1 - 4.1 7.4 12.5 1.8 8.6 1.6 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region RT_RNaseH_2 PF17919.1 CDO69317.1 - 1.2e-17 63.8 0.0 1.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO69317.1 - 9.5e-08 32.3 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 CDO69318.1 - 9.3e-10 38.7 0.1 1.9e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO69318.1 - 4.4e-05 23.3 0.0 8.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 CDO69318.1 - 0.015 15.3 1.4 0.029 14.4 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle FAM199X PF15814.5 CDO69318.1 - 4.1 6.4 7.3 5.9 5.8 7.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X Pirin_C PF05726.13 CDO69319.1 - 6.7e-16 58.5 0.0 9.8e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Transposase_21 PF02992.14 CDO69320.1 - 3.5e-08 33.0 0.0 7.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4214 PF13946.6 CDO69320.1 - 0.16 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) Velvet PF11754.8 CDO69321.1 - 1.9e-27 96.8 0.0 4.1e-27 95.7 0.0 1.5 1 1 0 1 1 1 1 Velvet factor F-box-like PF12937.7 CDO69322.1 - 0.00021 21.1 0.2 0.00044 20.1 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO69322.1 - 0.069 13.1 0.5 0.16 11.9 0.5 1.6 1 0 0 1 1 1 0 F-box domain Metallophos PF00149.28 CDO69323.1 - 1.3e-15 58.5 0.0 3.4e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDO69323.1 - 3e-05 24.3 0.0 0.0079 16.4 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain AKNA PF12443.8 CDO69324.1 - 0.008 16.8 0.8 0.032 14.9 0.8 2.0 1 0 0 1 1 1 1 AT-hook-containing transcription factor ABC_tran_CTD PF16326.5 CDO69324.1 - 1.2 9.5 5.2 0.66 10.3 0.7 2.6 1 1 2 3 3 3 0 ABC transporter C-terminal domain Nnf1 PF03980.14 CDO69325.1 - 4.6e-16 59.2 3.5 7e-16 58.6 3.5 1.3 1 0 0 1 1 1 1 Nnf1 ZapB PF06005.12 CDO69325.1 - 0.44 11.0 9.0 0.098 13.1 5.5 1.7 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CDO69325.1 - 0.78 9.6 6.7 0.51 10.1 3.7 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF789 PF05623.12 CDO69326.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF789) zf-C3HC4_2 PF13923.6 CDO69327.1 - 6.6e-07 29.1 2.4 6.6e-07 29.1 2.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO69327.1 - 1.4e-06 28.2 2.6 1.4e-06 28.2 2.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDO69327.1 - 1.5e-06 28.0 2.3 3.2e-06 26.9 2.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO69327.1 - 2.5e-05 24.1 4.8 5.4e-05 23.1 4.8 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDO69327.1 - 3.2e-05 23.7 8.9 0.00024 20.9 8.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDO69327.1 - 7.7e-05 22.8 3.2 7.7e-05 22.8 3.2 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CDO69327.1 - 0.0008 19.7 12.4 0.0083 16.4 12.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 CDO69327.1 - 0.0012 18.7 0.6 0.0028 17.5 0.6 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CDO69327.1 - 0.0099 16.0 2.9 0.02 15.0 2.9 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 CDO69327.1 - 0.011 15.6 1.5 0.011 15.6 1.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CDO69327.1 - 0.56 10.5 5.2 2 8.8 5.2 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CDO69327.1 - 2.2 8.0 5.4 0.15 11.7 0.3 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Nucleopor_Nup85 PF07575.13 CDO69328.1 - 1.7e-51 175.5 0.0 3.8e-32 111.6 0.0 2.0 2 0 0 2 2 2 2 Nup85 Nucleoporin GGDEF PF00990.21 CDO69328.1 - 0.19 11.4 0.0 0.48 10.2 0.0 1.6 2 0 0 2 2 2 0 Diguanylate cyclase, GGDEF domain CENP-T_C PF15511.6 CDO69329.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CDO69329.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CDO69329.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CDO69329.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDO69329.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CDO69329.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 CDO69330.1 - 9.7e-50 168.3 3.9 1.1e-49 168.2 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CDO69330.1 - 1.9e-05 24.7 0.1 3.7e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CDO69330.1 - 4.3e-05 23.8 0.0 7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CDO69330.1 - 0.00021 21.9 1.8 0.00027 21.5 1.8 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CDO69330.1 - 0.0026 18.0 0.1 0.0055 17.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Carb_kinase PF01256.17 CDO69331.1 - 1.6e-45 155.5 0.0 5.9e-44 150.4 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase GMC_oxred_N PF00732.19 CDO69332.1 - 2.8e-66 223.9 0.0 3.4e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CDO69332.1 - 1.9e-05 23.9 0.2 0.0079 15.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CDO69332.1 - 0.0018 18.5 0.0 0.0089 16.2 0.0 2.3 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CDO69332.1 - 0.0038 16.5 0.1 0.86 8.8 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDO69332.1 - 0.006 16.2 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDO69332.1 - 0.0081 15.4 0.0 0.092 12.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CDO69332.1 - 0.021 13.9 0.1 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 CDO69332.1 - 0.031 13.5 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Oxidored_molyb PF00174.19 CDO69334.1 - 5e-26 91.4 0.0 8.7e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CDO69334.1 - 2.6e-23 82.5 3.6 1.6e-20 73.5 0.1 2.4 1 1 1 2 2 2 2 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 CDO69334.1 - 2.6e-22 79.5 0.0 1.8e-21 76.8 0.0 2.4 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 CDO69334.1 - 1.9e-14 53.6 0.0 4.6e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 CDO69334.1 - 0.0044 17.2 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain TPR_19 PF14559.6 CDO69335.1 - 2.8e-14 53.4 25.1 0.00013 22.4 0.1 9.1 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDO69335.1 - 2.5e-10 39.7 16.2 0.79 10.1 0.0 10.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDO69335.1 - 1.5e-09 38.3 28.4 0.0055 17.3 0.0 8.4 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDO69335.1 - 1.5e-08 34.8 29.3 0.00012 22.2 0.6 9.3 8 2 1 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDO69335.1 - 3e-07 30.0 31.2 0.63 10.3 0.0 10.7 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDO69335.1 - 4.2e-07 29.9 2.5 4.1 8.0 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO69335.1 - 2e-06 27.4 15.2 1.3 9.2 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CDO69335.1 - 2.4e-06 28.0 1.8 0.0057 17.1 0.0 4.2 3 1 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_1 PF00515.28 CDO69335.1 - 4.9e-06 26.1 16.9 5.4 7.0 0.1 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDO69335.1 - 4e-05 24.1 37.3 0.16 12.8 0.1 11.5 11 2 1 13 13 10 2 Tetratricopeptide repeat TPR_20 PF14561.6 CDO69335.1 - 0.0091 16.3 8.1 0.25 11.7 0.2 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat SNAP PF14938.6 CDO69335.1 - 0.032 13.7 0.4 0.032 13.7 0.4 2.5 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 CDO69335.1 - 0.038 14.2 17.5 3.4 8.0 0.1 7.0 6 3 2 9 9 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CDO69335.1 - 0.1 12.8 0.0 0.1 12.8 0.0 5.9 6 1 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDO69335.1 - 0.2 12.3 17.0 0.75 10.6 0.0 8.3 12 0 0 12 12 9 0 Tetratricopeptide repeat NARP1 PF12569.8 CDO69335.1 - 0.26 10.1 0.0 0.26 10.1 0.0 3.7 4 2 1 5 5 5 0 NMDA receptor-regulated protein 1 TPR_11 PF13414.6 CDO69335.1 - 0.4 10.4 15.0 2.4 7.9 0.1 6.4 8 0 0 8 8 8 0 TPR repeat DUF4680 PF15730.5 CDO69335.1 - 1.9 8.8 5.1 0.43 10.9 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) TPPII_N PF12583.8 CDO69335.1 - 6.3 7.4 6.2 0.33 11.5 0.2 1.9 2 0 0 2 2 1 0 Tripeptidyl peptidase II N terminal PAP2 PF01569.21 CDO69337.1 - 8.7e-09 35.3 9.4 1.2e-08 34.8 9.4 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF2070 PF09843.9 CDO69337.1 - 0.15 10.3 0.8 0.16 10.2 0.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 CDO69338.1 - 3.9e-33 114.9 29.5 3.9e-33 114.9 29.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 CDO69338.1 - 0.00015 21.7 1.5 0.023 14.5 0.1 2.8 2 1 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Vpu PF00558.19 CDO69338.1 - 0.11 12.2 0.7 0.43 10.4 0.1 2.2 2 0 0 2 2 2 0 Vpu protein Antistasin PF02822.14 CDO69338.1 - 0.21 12.2 0.2 0.37 11.5 0.2 1.3 1 0 0 1 1 1 0 Antistasin family BCS1_N PF08740.11 CDO69340.1 - 7.7e-26 91.2 3.5 2.8e-24 86.2 2.4 2.6 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 CDO69340.1 - 4.4e-15 56.3 0.0 2.3e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDO69340.1 - 5.5e-05 23.0 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDO69340.1 - 0.0075 16.7 0.4 0.085 13.2 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CDO69340.1 - 0.012 14.8 0.0 0.034 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 CDO69340.1 - 0.098 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CDO69340.1 - 0.15 11.4 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin BCS1_N PF08740.11 CDO69341.1 - 6.5e-36 124.1 0.2 1.2e-35 123.2 0.2 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CDO69341.1 - 2.2e-15 57.3 0.0 1.6e-14 54.4 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDO69341.1 - 0.00051 20.5 0.0 0.0014 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CDO69341.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CDO69341.1 - 0.0022 17.2 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 CDO69341.1 - 0.011 15.6 0.1 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 CDO69341.1 - 0.047 14.1 0.1 1.2 9.6 0.0 2.8 3 0 0 3 3 3 0 RNA helicase ATPase PF06745.13 CDO69341.1 - 0.057 12.8 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 CDO69341.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CDO69341.1 - 0.11 12.7 0.0 0.69 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDO69341.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CDO69341.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CDO69341.1 - 0.15 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 CDO69341.1 - 0.22 11.4 0.0 0.47 10.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea zf-C2H2 PF00096.26 CDO69342.1 - 2.2e-09 37.2 4.0 0.00043 20.6 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CDO69342.1 - 5.5e-08 32.4 4.2 3.1e-05 23.6 0.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CDO69342.1 - 3.5e-07 30.5 3.0 0.007 17.1 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDO69342.1 - 0.0029 18.0 10.3 2.3 8.8 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDO69342.1 - 0.13 12.3 2.2 0.17 11.9 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger CsbD PF05532.12 CDO69343.1 - 2.1e-15 56.3 10.2 5.3e-09 35.8 0.9 2.1 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.12 CDO69344.1 - 5.3e-16 58.3 13.0 1.5e-08 34.4 2.9 2.0 1 1 1 2 2 2 2 CsbD-like Plavaka PF18759.1 CDO69347.1 - 2.7e-26 92.6 0.1 8.8e-25 87.6 0.0 2.5 2 0 0 2 2 2 1 Plavaka transposase zf-C2H2_6 PF13912.6 CDO69347.1 - 0.093 12.8 1.0 0.34 11.0 1.0 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Glyco_hydro_16 PF00722.21 CDO69351.1 - 5.1e-07 29.3 0.0 8.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WD40 PF00400.32 CDO69352.1 - 5.9e-18 64.9 8.8 0.024 15.5 1.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CDO69352.1 - 0.03 13.3 0.1 0.3 10.0 0.0 2.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Rav1p_C PF12234.8 CDO69352.1 - 0.22 9.9 0.1 0.29 9.5 0.1 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal SIR2 PF02146.17 CDO69353.1 - 4.7e-30 104.8 0.0 6.5e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF1768 PF08719.11 CDO69354.1 - 0.081 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) DUF4451 PF14616.6 CDO69355.1 - 0.00014 22.0 1.3 0.8 9.9 0.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4451) zf-ribbon_3 PF13248.6 CDO69355.1 - 0.048 13.1 1.2 9.6 5.8 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 CDO69355.1 - 0.057 13.4 4.0 4.3 7.4 1.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-dskA_traR PF01258.17 CDO69355.1 - 0.12 12.3 0.9 2.5 8.1 0.1 2.6 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger C1_1 PF00130.22 CDO69355.1 - 0.44 10.5 4.0 5.7 6.9 0.1 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.6 CDO69355.1 - 2.2 8.1 4.6 9.9 6.0 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-CW PF07496.15 CDO69355.1 - 5 7.2 6.2 3.7 7.6 1.2 2.6 2 0 0 2 2 2 0 CW-type Zinc Finger Methyltransf_16 PF10294.9 CDO69356.1 - 1.5e-15 57.4 0.0 2e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 CDO69356.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.12 CDO69356.1 - 0.038 14.7 0.0 0.084 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 CDO69356.1 - 0.041 13.6 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.6 CDO69356.1 - 0.055 14.2 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CDO69356.1 - 0.057 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 CDO69356.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pkinase PF00069.25 CDO69357.1 - 5.7e-42 143.9 0.0 2.6e-37 128.6 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69357.1 - 2.3e-17 63.2 0.0 3.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO69357.1 - 1.4e-06 28.5 0.1 3e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO69357.1 - 0.00024 20.1 0.0 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDO69357.1 - 0.00026 20.4 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDO69357.1 - 0.00068 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDO69357.1 - 0.021 13.6 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CDO69357.1 - 0.22 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 CDO69357.1 - 0.23 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cript PF10235.9 CDO69358.1 - 9.9e-29 99.8 4.4 9.9e-29 99.8 4.4 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 CDO69358.1 - 0.21 12.0 18.7 2.6 8.5 18.7 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zinc_ribbon_2 PF13240.6 CDO69358.1 - 1.6 8.6 16.4 3.6 7.4 5.9 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DUF1272 PF06906.11 CDO69358.1 - 1.7 8.8 7.3 0.6 10.2 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf_UBZ PF18439.1 CDO69358.1 - 2.8 7.6 8.1 6.1 6.5 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger NOB1_Zn_bind PF08772.11 CDO69358.1 - 4.5 7.5 12.7 1.5 9.0 4.7 2.9 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like IgaA PF07095.11 CDO69359.1 - 0.021 12.9 0.2 0.027 12.5 0.2 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Tat PF00539.18 CDO69359.1 - 0.095 12.9 1.5 0.27 11.4 1.5 1.7 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) DUF3086 PF11285.8 CDO69359.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Sec7 PF01369.20 CDO69361.1 - 1.8e-30 106.0 0.0 3.1e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain GATA PF00320.27 CDO69361.1 - 3.3e-14 52.2 2.9 6.3e-14 51.3 2.9 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 CDO69361.1 - 1.4e-11 44.0 0.7 3e-11 42.9 0.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Asp PF00026.23 CDO69362.1 - 4.4e-80 269.4 10.7 5.2e-80 269.2 10.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO69362.1 - 1.3e-11 45.1 8.3 6.2e-10 39.6 6.3 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 CDO69362.1 - 0.0039 17.7 0.0 1.2 9.7 0.0 2.9 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO69362.1 - 0.0051 17.4 0.1 0.085 13.5 0.1 2.6 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 CDO69362.1 - 0.035 13.9 0.4 0.31 10.8 0.4 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Peptidase_A22B PF04258.13 CDO69363.1 - 1.8e-71 241.0 4.5 2.1e-71 240.7 4.5 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 CDO69363.1 - 1.3e-06 28.1 2.4 3.1e-06 26.9 2.4 1.6 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease SLAC1 PF03595.17 CDO69364.1 - 2.4e-70 237.3 38.1 3.1e-70 237.0 38.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.17 CDO69365.1 - 4e-71 239.9 51.4 4.6e-71 239.7 51.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PI3_PI4_kinase PF00454.27 CDO69366.1 - 8.5e-37 127.3 0.0 1.8e-36 126.2 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RRM_1 PF00076.22 CDO69368.1 - 4.3e-13 48.9 0.0 2e-05 24.3 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDO69368.1 - 0.00038 20.5 0.0 0.00073 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif CI-B14_5a PF07347.12 CDO69369.1 - 0.045 13.6 0.9 0.1 12.5 0.3 1.9 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Peptidase_S10 PF00450.22 CDO69371.1 - 3.3e-72 244.2 3.5 4.1e-72 243.9 3.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PP2C PF00481.21 CDO69373.1 - 3.4e-63 213.7 0.1 2.2e-49 168.4 0.0 2.0 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 CDO69373.1 - 0.0034 17.3 0.3 0.049 13.6 0.3 2.5 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) G_glu_transpept PF01019.21 CDO69374.1 - 2.9e-156 521.3 0.0 6.3e-155 516.8 0.0 2.1 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Cellulase PF00150.18 CDO69374.1 - 1.3e-27 97.0 7.2 1.9e-27 96.5 7.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 CDO69374.1 - 3.4e-13 49.3 11.2 3.4e-13 49.3 11.2 1.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 CDO69374.1 - 0.00023 20.4 0.0 0.00048 19.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 CDO69374.1 - 0.00077 19.2 0.5 0.0012 18.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Asp PF00026.23 CDO69375.1 - 7.5e-12 45.3 0.0 8.3e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 CDO69375.1 - 0.0097 15.7 0.0 0.0097 15.7 0.0 1.1 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Kisspeptin PF15152.6 CDO69376.1 - 0.44 11.3 3.9 0.32 11.8 0.3 2.7 2 0 0 2 2 2 0 Kisspeptin RsfS PF02410.15 CDO69378.1 - 1.1e-06 28.9 0.0 1.9e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation SHR3_chaperone PF08229.11 CDO69379.1 - 2.9e-38 130.7 0.0 5.1e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein SH3 Linker_histone PF00538.19 CDO69380.1 - 1.2e-10 41.6 0.0 1.2e-10 41.6 0.0 3.1 4 0 0 4 4 4 1 linker histone H1 and H5 family CAP_N PF01213.19 CDO69382.1 - 1.9e-114 382.4 0.5 2.6e-114 382.0 0.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CDO69382.1 - 1.2e-54 184.2 6.5 6.8e-54 181.7 6.5 2.0 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DEC-1_N PF04625.13 CDO69382.1 - 0.83 8.6 29.4 1.7 7.6 5.6 2.2 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region TBCC PF07986.12 CDO69382.1 - 1 9.1 8.3 0.56 9.9 4.1 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor C UQ_con PF00179.26 CDO69385.1 - 9.9e-45 151.6 0.2 1.2e-44 151.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDO69385.1 - 4.5e-05 23.2 0.0 5.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CDO69385.1 - 0.0066 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain RVT_1 PF00078.27 CDO69391.1 - 8e-17 61.5 0.0 3e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO69391.1 - 3.5e-09 36.5 0.8 8.8e-09 35.2 0.1 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 CDO69391.1 - 2.9e-05 24.7 0.0 8.9e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase IL28A PF15177.6 CDO69391.1 - 0.01 15.7 3.4 4.8 7.0 0.1 3.3 3 0 0 3 3 3 0 Interleukin-28A Exo_endo_phos PF03372.23 CDO69391.1 - 0.018 14.6 0.1 0.052 13.0 0.1 1.8 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family FPP PF05911.11 CDO69391.1 - 0.097 10.8 0.1 0.15 10.2 0.1 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil CLZ PF16526.5 CDO69391.1 - 0.21 12.0 0.6 4.3 7.8 0.9 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels OmdA PF13376.6 CDO69391.1 - 0.33 11.0 6.0 5.6 7.1 0.2 3.4 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Apolipoprotein PF01442.18 CDO69391.1 - 1.1 9.1 9.6 0.45 10.4 4.2 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Plavaka PF18759.1 CDO69394.1 - 4.4e-125 417.2 0.0 6.1e-125 416.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF4219 PF13961.6 CDO69395.1 - 0.033 13.8 0.6 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) KDZ PF18758.1 CDO69396.1 - 4.8e-29 101.6 1.0 5.8e-29 101.3 0.1 1.5 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase TMEM247 PF15444.6 CDO69397.1 - 2 8.4 5.7 2.8 7.9 5.5 1.3 1 1 0 1 1 1 0 Transmembrane protein 247 gag-asp_proteas PF13975.6 CDO69398.1 - 5.5e-07 30.1 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO69398.1 - 1.2e-05 25.8 0.0 2.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CDO69398.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 CDO69398.1 - 0.004 17.2 4.3 0.0087 16.1 4.3 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 CDO69398.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease CDC45 PF02724.14 CDO69398.1 - 3.9 5.7 11.0 5.5 5.2 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NADH_B2 PF14813.6 CDO69401.1 - 0.00047 19.9 0.3 0.00054 19.7 0.3 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 G-alpha PF00503.20 CDO69402.1 - 1.7e-93 313.6 0.0 2e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDO69402.1 - 1e-14 54.4 0.0 5.1e-11 42.3 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CDO69402.1 - 1.6e-05 25.1 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CDO69402.1 - 0.00012 21.6 0.1 0.24 10.7 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 CDO69402.1 - 0.0028 17.4 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 CDO69402.1 - 0.0038 17.1 0.1 0.32 10.7 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein TniB PF05621.11 CDO69402.1 - 0.023 14.1 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 CDO69402.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CDO69402.1 - 0.11 12.0 0.0 17 5.0 0.0 2.5 2 1 0 2 2 2 0 Ras family DUF755 PF05501.11 CDO69405.1 - 0.0026 18.0 7.5 0.0032 17.8 7.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF755) U79_P34 PF03064.16 CDO69405.1 - 0.025 14.0 11.9 0.03 13.7 11.9 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3619 PF12279.8 CDO69405.1 - 0.059 13.7 4.7 0.062 13.6 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) UPF0565 PF10561.9 CDO69405.1 - 0.13 11.5 1.5 0.13 11.4 1.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF1664 PF07889.12 CDO69405.1 - 0.13 12.3 2.2 0.12 12.4 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 CDO69405.1 - 0.58 10.8 8.2 0.63 10.7 8.2 1.0 1 0 0 1 1 1 0 Initiation control protein YabA PIEZO PF15917.5 CDO69405.1 - 0.61 9.5 10.7 0.67 9.4 10.7 1.1 1 0 0 1 1 1 0 Piezo HemX PF04375.14 CDO69405.1 - 0.67 9.2 11.0 0.7 9.1 11.0 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DDRGK PF09756.9 CDO69405.1 - 0.88 9.1 17.8 0.97 9.0 17.8 1.1 1 0 0 1 1 1 0 DDRGK domain Ax_dynein_light PF10211.9 CDO69405.1 - 0.96 9.4 13.6 1.1 9.2 13.6 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain YlqD PF11068.8 CDO69405.1 - 0.96 9.8 11.9 1.1 9.6 11.9 1.1 1 0 0 1 1 1 0 YlqD protein RF-1 PF00472.20 CDO69405.1 - 1 9.3 10.5 1.4 8.8 10.5 1.3 1 0 0 1 1 1 0 RF-1 domain Baculo_PP31 PF05311.11 CDO69405.1 - 1.2 8.6 8.5 1.2 8.5 8.5 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF1764 PF08576.10 CDO69405.1 - 1.4 9.9 9.1 1.7 9.6 9.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Herpes_UL6 PF01763.16 CDO69405.1 - 2 6.9 5.8 2.1 6.8 5.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Vfa1 PF08432.10 CDO69405.1 - 2.2 8.6 14.8 2.4 8.5 14.8 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TSA PF03249.13 CDO69405.1 - 2.3 6.9 5.7 2.5 6.8 5.7 1.0 1 0 0 1 1 1 0 Type specific antigen betaPIX_CC PF16523.5 CDO69405.1 - 2.5 8.0 14.4 4.7 7.1 14.2 1.5 1 1 0 1 1 1 0 betaPIX coiled coil ATP11 PF06644.11 CDO69405.1 - 2.9 7.6 11.8 3.1 7.5 11.8 1.0 1 0 0 1 1 1 0 ATP11 protein ALMT PF11744.8 CDO69405.1 - 3 6.6 6.6 3.2 6.5 6.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Ku_C PF03730.14 CDO69405.1 - 3 8.6 10.9 4.2 8.1 10.9 1.2 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm DUF4407 PF14362.6 CDO69405.1 - 3.1 7.1 11.6 3.4 6.9 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PV-1 PF06637.11 CDO69405.1 - 3.2 6.5 13.6 3.4 6.4 13.6 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) OmpH PF03938.14 CDO69405.1 - 3.6 7.9 18.2 3.7 7.9 18.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GrpE PF01025.19 CDO69405.1 - 3.9 7.1 15.0 4.4 6.9 15.0 1.1 1 0 0 1 1 1 0 GrpE XRN_M PF17846.1 CDO69405.1 - 3.9 6.3 6.6 4.4 6.2 6.6 1.0 1 0 0 1 1 1 0 Xrn1 helical domain EMP24_GP25L PF01105.24 CDO69405.1 - 4.3 7.3 6.5 5.1 7.0 6.5 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Herpes_UL25 PF01499.16 CDO69405.1 - 5.4 5.4 6.8 6 5.3 6.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family COG2 PF06148.11 CDO69405.1 - 6.1 6.9 8.8 7 6.7 8.8 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Folliculin PF11704.8 CDO69405.1 - 6.4 6.6 7.4 7.2 6.4 7.4 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport TMEM119 PF15724.5 CDO69405.1 - 7.2 6.6 11.4 7.9 6.5 11.4 1.0 1 0 0 1 1 1 0 TMEM119 family Peptidase_S49_N PF08496.10 CDO69405.1 - 7.5 6.6 11.1 8.2 6.5 11.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LPP PF04728.13 CDO69405.1 - 8.6 6.8 12.7 41 4.7 12.7 2.0 1 1 0 1 1 1 0 Lipoprotein leucine-zipper Integrase_H2C2 PF17921.1 CDO69406.1 - 1.5e-14 53.8 0.3 3.5e-14 52.6 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO69406.1 - 2.1e-12 47.3 0.0 3.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDO69406.1 - 2.1e-07 31.0 0.1 4.3e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDO69406.1 - 0.039 13.7 0.2 0.095 12.5 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain Plavaka PF18759.1 CDO69407.1 - 1.2e-26 93.7 0.0 2e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF3847 PF12958.7 CDO69408.1 - 0.074 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) DLH PF01738.18 CDO69409.1 - 5.6e-23 81.6 0.0 6.6e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family NmrA PF05368.13 CDO69410.1 - 4e-21 75.6 0.0 5.3e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CDO69410.1 - 1.1e-17 64.6 0.0 1.6e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CDO69410.1 - 0.00012 21.2 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CDO69410.1 - 0.00055 19.5 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CDO69410.1 - 0.00086 19.3 0.1 0.063 13.2 0.0 2.3 2 0 0 2 2 2 1 KR domain ETF PF01012.21 CDO69410.1 - 0.088 12.7 0.2 1.7 8.5 0.3 2.1 2 0 0 2 2 2 0 Electron transfer flavoprotein domain EI24 PF07264.11 CDO69411.1 - 0.007 16.6 9.9 0.011 16.0 9.9 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) CPBP PF02517.16 CDO69411.1 - 0.051 14.0 0.2 0.051 14.0 0.2 1.7 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease Phage_holin_2_4 PF16082.5 CDO69411.1 - 0.82 9.4 4.1 1.6 8.5 2.9 2.0 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Mito_carr PF00153.27 CDO69412.1 - 8.9e-44 147.4 3.2 1.2e-16 60.3 0.0 3.7 3 1 1 4 4 4 3 Mitochondrial carrier protein MFS_1 PF07690.16 CDO69413.1 - 6.7e-23 81.2 41.2 1.6e-21 76.6 41.2 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 CDO69413.1 - 0.13 12.3 0.2 0.13 12.3 0.2 4.5 4 2 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III MFS_1 PF07690.16 CDO69415.1 - 2.3e-30 105.7 40.4 2.9e-30 105.4 40.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HMGL-like PF00682.19 CDO69416.1 - 9.5e-55 186.0 1.5 1.7e-29 103.2 0.0 2.9 2 1 1 3 3 3 2 HMGL-like LeuA_dimer PF08502.10 CDO69416.1 - 9e-11 41.8 0.5 1.2e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain Ribosomal_S5 PF00333.20 CDO69416.1 - 0.0043 17.0 0.3 0.018 15.0 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Aminotran_1_2 PF00155.21 CDO69417.1 - 5.6e-34 117.9 0.0 7.4e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CDO69417.1 - 0.00011 20.8 0.0 0.00026 19.7 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CDO69417.1 - 0.00021 20.7 0.0 0.00047 19.6 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CDO69417.1 - 0.0027 17.0 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CDO69417.1 - 0.0099 14.9 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CDO69418.1 - 0.18 10.9 0.0 0.19 10.9 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class I and II Dynamin_N PF00350.23 CDO69419.1 - 2.4e-16 60.2 5.7 2.6e-16 60.2 0.0 3.3 3 2 1 4 4 3 1 Dynamin family MMR_HSR1 PF01926.23 CDO69419.1 - 1.5e-06 28.3 0.0 0.00054 20.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CDO69419.1 - 0.00039 20.9 2.6 0.00056 20.4 0.0 2.6 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 CDO69419.1 - 0.00042 20.3 0.3 0.0016 18.3 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CDO69419.1 - 0.0026 18.1 0.1 0.027 14.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 CDO69419.1 - 0.021 14.0 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SSE PF00437.20 CDO69419.1 - 0.024 13.7 0.1 0.059 12.4 0.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ADIP PF11559.8 CDO69419.1 - 0.033 14.3 11.9 0.044 13.9 2.3 2.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding AIG1 PF04548.16 CDO69419.1 - 0.034 13.5 0.1 0.12 11.7 0.1 1.9 1 0 0 1 1 1 0 AIG1 family Zeta_toxin PF06414.12 CDO69419.1 - 0.046 13.0 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 CDO69419.1 - 0.069 12.5 0.2 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family IIGP PF05049.13 CDO69419.1 - 0.082 11.9 0.1 0.96 8.4 0.1 2.7 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 CDO69419.1 - 0.083 13.3 3.2 0.18 12.2 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 CDO69419.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CDO69419.1 - 0.11 12.9 0.1 0.11 12.9 0.1 3.4 2 1 0 3 3 2 0 AAA domain Spc24 PF08286.11 CDO69419.1 - 0.52 10.6 7.7 5.3 7.3 0.9 3.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PI3K_P85_iSH2 PF16454.5 CDO69419.1 - 0.97 9.0 9.2 5.2 6.6 1.3 2.6 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APG6_N PF17675.1 CDO69419.1 - 1.4 9.5 19.1 0.61 10.6 1.5 3.0 3 0 0 3 3 2 0 Apg6 coiled-coil region Atg14 PF10186.9 CDO69419.1 - 1.5 7.8 15.8 3.7 6.6 1.5 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 CDO69419.1 - 7.7 7.0 13.5 5.9 7.4 4.5 3.5 3 0 0 3 3 3 0 Cell division protein ZapB Aminotran_1_2 PF00155.21 CDO69420.1 - 1.5e-12 47.4 0.0 1.7e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CARD PF00619.21 CDO69421.1 - 0.021 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Caspase recruitment domain Fzo_mitofusin PF04799.13 CDO69421.1 - 0.08 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region Aminotran_1_2 PF00155.21 CDO69423.1 - 1.4e-16 60.6 0.0 1.4e-14 54.1 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II Pkinase PF00069.25 CDO69424.1 - 7.7e-12 45.1 0.0 2.2e-10 40.3 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69424.1 - 6.2e-06 25.7 0.1 3.4e-05 23.3 0.1 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CDO69424.1 - 0.041 13.8 0.9 0.15 11.9 0.1 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3410 PF11890.8 CDO69425.1 - 0.0006 19.6 0.2 0.0015 18.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3410) Pheromone PF08015.11 CDO69425.1 - 0.061 14.4 3.2 0.098 13.7 3.2 1.4 1 0 0 1 1 1 0 Fungal mating-type pheromone DUF4349 PF14257.6 CDO69425.1 - 0.066 12.7 0.2 0.16 11.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) TssO PF17561.2 CDO69425.1 - 0.13 12.4 2.6 0.48 10.5 0.4 2.2 2 1 0 2 2 2 0 Type VI secretion system, TssO Pkinase PF00069.25 CDO69426.1 - 7.8e-13 48.4 0.1 9.1e-10 38.3 0.0 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69426.1 - 1.7e-06 27.6 0.0 1.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3425 PF11905.8 CDO69426.1 - 0.057 13.4 1.5 0.46 10.5 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3425) CPDase PF07823.11 CDO69426.1 - 0.085 12.6 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Pkinase_fungal PF17667.1 CDO69426.1 - 0.1 11.4 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF2187 PF09953.9 CDO69426.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) Melittin PF01372.17 CDO69427.1 - 0.12 12.4 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Melittin DUF3416 PF11896.8 CDO69428.1 - 0.026 14.8 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) Pkinase PF00069.25 CDO69429.1 - 1.3e-13 51.0 0.0 2.4e-12 46.8 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69429.1 - 8.9e-05 21.9 0.0 0.00017 21.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDO69430.1 - 1.5e-16 60.6 0.0 2.8e-14 53.1 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69430.1 - 1e-06 28.3 0.8 3e-06 26.7 0.3 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO69430.1 - 0.018 13.8 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DAHP_snth_FXD PF18152.1 CDO69430.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain WD40 PF00400.32 CDO69431.1 - 2.9e-16 59.6 19.0 0.00045 21.0 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO69431.1 - 4.6e-14 52.5 1.5 0.0022 18.2 0.1 4.2 4 0 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDO69431.1 - 0.0013 18.7 0.1 0.041 13.8 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ORC6 PF05460.13 CDO69431.1 - 6.1 6.0 9.3 10 5.3 9.3 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Bromodomain PF00439.25 CDO69432.1 - 1.5e-23 82.7 0.5 3.8e-23 81.4 0.4 1.8 1 1 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 CDO69432.1 - 4.3e-06 26.6 0.0 8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated UbiA PF01040.18 CDO69434.1 - 3.6e-29 101.8 12.3 5.6e-29 101.2 12.3 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.18 CDO69436.1 - 3e-28 98.8 14.6 4.3e-28 98.3 14.6 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family RhodobacterPufX PF11511.8 CDO69436.1 - 2.4 7.8 5.5 0.49 10.0 0.8 2.3 3 0 0 3 3 3 0 Intrinsic membrane protein PufX Methyltransf_12 PF08242.12 CDO69438.1 - 9e-09 36.0 0.0 1.5e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO69438.1 - 9.5e-09 35.9 0.0 1.8e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO69438.1 - 2.3e-07 31.4 0.0 4.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO69438.1 - 2.5e-06 27.4 0.0 4.7e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO69438.1 - 0.00012 21.9 0.0 0.0003 20.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 CDO69438.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase p450 PF00067.22 CDO69439.1 - 1.4e-58 198.8 0.0 4.6e-58 197.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 CDO69440.1 - 2e-22 79.4 0.0 7.7e-20 70.9 0.4 2.7 2 1 1 3 3 3 3 AMP-binding enzyme Aldose_epim PF01263.20 CDO69442.1 - 2.3e-46 158.5 0.4 3.4e-46 157.9 0.4 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase FAD_binding_3 PF01494.19 CDO69443.1 - 2.4e-12 46.8 2.6 1.2e-06 28.1 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain Trp_halogenase PF04820.14 CDO69443.1 - 9.4e-06 24.7 0.3 5.5e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 CDO69443.1 - 0.0012 19.1 0.2 0.0039 17.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDO69443.1 - 0.0018 17.6 0.5 0.011 14.9 0.1 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO69443.1 - 0.015 15.3 1.8 0.26 11.3 0.3 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 CDO69443.1 - 0.024 14.2 3.1 0.087 12.4 3.1 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 CDO69444.1 - 7.9e-57 192.9 0.0 1.2e-56 192.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO69444.1 - 9.6e-32 110.5 0.0 1.8e-31 109.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CDO69444.1 - 5.1e-05 23.4 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CDO69444.1 - 0.00052 19.2 0.0 0.00094 18.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CDO69444.1 - 0.0012 18.5 1.1 0.0012 18.5 1.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CDO69444.1 - 0.0014 18.0 0.4 0.0036 16.6 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDO69444.1 - 0.0073 15.6 1.3 0.018 14.2 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDO69444.1 - 0.0097 15.0 3.0 0.028 13.5 1.2 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CDO69444.1 - 0.02 14.1 0.1 0.04 13.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 CDO69444.1 - 0.03 13.0 1.6 0.092 11.4 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein TmoB PF06234.12 CDO69444.1 - 0.15 12.2 0.0 7.4 6.7 0.0 2.7 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) Pyr_redox PF00070.27 CDO69444.1 - 0.97 10.0 3.2 4.9 7.8 0.4 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Helicase_C PF00271.31 CDO69447.1 - 7e-18 65.0 0.0 1.5e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDO69447.1 - 1.2e-05 25.2 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase E7 PF00527.18 CDO69447.1 - 0.31 11.3 2.9 2.6 8.3 0.5 2.5 2 0 0 2 2 2 0 E7 protein, Early protein Abhydrolase_6 PF12697.7 CDO69448.1 - 9.1e-11 42.8 0.5 6.7e-06 26.9 0.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family WD40 PF00400.32 CDO69449.1 - 9.4e-38 127.5 32.3 1.6e-09 38.2 0.0 11.8 13 0 0 13 13 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO69449.1 - 5.4e-26 90.7 0.7 0.0035 17.6 0.0 9.5 4 3 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 CDO69449.1 - 1.9e-07 31.2 0.1 4e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CDO69449.1 - 0.00015 22.1 0.0 0.0004 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cytochrom_D1 PF02239.16 CDO69449.1 - 0.0007 18.2 0.0 2.5 6.5 0.0 4.1 3 1 1 4 4 4 1 Cytochrome D1 heme domain WD40_like PF17005.5 CDO69449.1 - 0.00081 18.8 0.0 0.23 10.7 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 CDO69449.1 - 0.00084 18.4 0.6 4.5 6.1 0.0 4.8 3 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 CDO69449.1 - 0.0052 17.2 0.4 0.028 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain PALB2_WD40 PF16756.5 CDO69449.1 - 0.016 14.2 3.4 0.049 12.6 1.1 2.9 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 CDO69449.1 - 0.026 13.2 0.4 2.4 6.7 0.2 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 KAP_NTPase PF07693.14 CDO69449.1 - 0.11 11.7 1.2 0.2 10.9 0.6 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.6 CDO69449.1 - 0.14 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.7 CDO69450.1 - 8.9e-15 55.9 3.2 1.4e-14 55.2 3.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CDO69450.1 - 0.0034 16.4 0.1 0.0055 15.6 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Glyco_hydro_92 PF07971.12 CDO69451.1 - 2.7e-144 481.5 0.7 3.4e-144 481.2 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 CDO69451.1 - 1.2e-55 189.0 3.2 2e-55 188.3 3.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain GMC_oxred_N PF00732.19 CDO69452.1 - 8.9e-55 186.1 0.0 1.3e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO69452.1 - 2.5e-34 118.8 0.0 4.1e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CDO69452.1 - 0.0043 17.3 0.1 0.011 16.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CDO69452.1 - 0.022 13.8 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CDO69452.1 - 0.15 11.2 0.1 17 4.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDO69452.1 - 0.21 10.6 1.2 0.54 9.3 0.5 1.8 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_92 PF07971.12 CDO69453.1 - 1.6e-141 472.4 3.1 1.9e-141 472.2 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 CDO69453.1 - 1.2e-54 185.8 5.2 2e-54 185.0 5.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Prenyltrans PF00432.21 CDO69453.1 - 0.54 10.0 3.2 0.54 10.0 1.2 2.1 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Glyco_hydro_3 PF00933.21 CDO69454.1 - 9.7e-55 186.2 0.0 1.3e-54 185.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CDO69454.1 - 1.6e-43 149.0 0.0 2.7e-42 145.0 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CDO69454.1 - 2.2e-23 82.1 1.8 4.3e-23 81.2 1.8 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain SH3_9 PF14604.6 CDO69455.1 - 3.5e-05 23.6 0.1 7.3e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDO69455.1 - 0.00075 19.1 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDO69455.1 - 0.04 13.6 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain TFIIA PF03153.13 CDO69455.1 - 0.97 9.4 3.8 1.2 9.0 3.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4698 PF15769.5 CDO69455.1 - 1.3 8.0 3.7 2.6 7.0 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) MFS_1 PF07690.16 CDO69456.1 - 1.8e-21 76.4 30.2 2e-21 76.3 19.3 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_10 PF00331.20 CDO69458.1 - 6.8e-91 304.7 0.0 8.7e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 CDO69458.1 - 6.1e-08 32.5 3.7 6.1e-08 32.5 3.7 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain IMPDH PF00478.25 CDO69459.1 - 2.7e-133 444.3 0.0 7.1e-133 442.9 0.0 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CDO69459.1 - 9.5e-18 64.4 1.1 3.4e-09 37.0 0.0 3.1 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 CDO69459.1 - 3.1e-09 36.3 7.8 8.4e-09 34.9 7.8 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 CDO69459.1 - 8.9e-05 22.0 13.5 0.0048 16.3 10.7 2.6 2 1 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 CDO69459.1 - 0.00016 21.1 1.1 0.00044 19.6 1.1 1.7 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 CDO69459.1 - 0.0003 20.3 5.3 0.00073 19.1 1.0 2.6 2 1 1 3 3 3 1 Histidine biosynthesis protein HK PF02110.15 CDO69459.1 - 0.03 13.7 3.3 0.076 12.4 0.2 2.6 2 1 0 3 3 3 0 Hydroxyethylthiazole kinase family Aldolase PF01081.19 CDO69459.1 - 0.03 13.7 0.5 0.59 9.5 0.1 2.8 3 0 0 3 3 3 0 KDPG and KHG aldolase YpsA PF06908.11 CDO69459.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Dus PF01207.17 CDO69459.1 - 0.22 10.6 2.3 2.2 7.3 0.2 2.2 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) Glu_synthase PF01645.17 CDO69459.1 - 0.23 10.5 4.5 0.68 9.0 3.2 2.0 2 0 0 2 2 2 0 Conserved region in glutamate synthase G3P_antiterm PF04309.12 CDO69459.1 - 0.26 10.7 1.5 3.3 7.1 0.3 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Fez1 PF06818.15 CDO69460.1 - 0.84 10.0 11.4 3.2 8.2 11.4 2.0 1 0 0 1 1 1 0 Fez1 DUF4200 PF13863.6 CDO69460.1 - 3.9 7.9 12.4 5.2 7.5 3.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Glyco_hydro_61 PF03443.14 CDO69461.1 - 2.8e-65 220.1 0.3 5.6e-65 219.1 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DnaJ PF00226.31 CDO69461.1 - 1.2e-19 70.2 0.4 1.2e-19 70.2 0.4 2.6 3 0 0 3 3 2 1 DnaJ domain TPR_2 PF07719.17 CDO69461.1 - 4.8e-14 51.3 13.7 0.0034 17.4 0.1 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 CDO69461.1 - 5.1e-13 49.0 7.8 5.3e-05 23.3 0.1 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO69461.1 - 6.7e-13 49.0 16.8 0.0002 21.8 3.3 7.1 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 CDO69461.1 - 4.5e-11 42.6 12.4 0.13 13.1 0.4 6.4 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 CDO69461.1 - 5.8e-11 41.7 11.3 0.00017 21.3 0.2 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDO69461.1 - 1.7e-10 41.4 11.5 3.9e-06 27.4 1.9 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO69461.1 - 3e-10 39.6 7.1 5.9e-06 25.9 1.9 5.9 5 1 1 6 6 6 3 TPR repeat TPR_12 PF13424.6 CDO69461.1 - 8e-06 26.1 9.3 0.0086 16.3 0.5 4.5 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO69461.1 - 0.00089 19.1 3.7 3.3 8.0 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDO69461.1 - 0.0012 18.6 7.7 0.11 12.4 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDO69461.1 - 0.0012 19.0 3.0 0.011 16.1 0.4 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDO69461.1 - 0.0021 18.6 19.9 0.66 10.7 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat BTAD PF03704.17 CDO69461.1 - 0.0043 17.5 7.3 0.015 15.7 0.2 3.7 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 CDO69461.1 - 0.023 15.0 7.1 0.27 11.6 0.2 3.9 3 2 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDO69461.1 - 0.095 12.8 2.0 0.83 9.8 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Acetyltransf_9 PF13527.7 CDO69461.1 - 0.12 12.5 0.5 5.6 7.0 0.1 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TPR_8 PF13181.6 CDO69461.1 - 0.12 12.6 18.0 0.36 11.2 0.1 6.3 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDO69461.1 - 3 8.7 11.3 22 6.0 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TLP1_add_C PF18313.1 CDO69464.1 - 0.0047 16.9 0.0 0.042 13.8 0.0 2.2 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain TLP1_add_C PF18313.1 CDO69465.1 - 0.00055 19.8 0.0 0.0047 16.8 0.0 2.2 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain TIP49 PF06068.13 CDO69466.1 - 6.1e-160 532.2 0.0 7.2e-160 531.9 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDO69466.1 - 3.2e-19 68.8 0.0 6.7e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CDO69466.1 - 5e-11 43.2 0.0 1.1e-07 32.4 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDO69466.1 - 5.2e-10 39.3 0.0 2.8e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDO69466.1 - 2.3e-07 31.1 0.1 0.01 16.1 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CDO69466.1 - 2e-06 28.3 0.0 2.2e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CDO69466.1 - 3.8e-06 26.9 0.1 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CDO69466.1 - 0.0015 18.8 0.1 0.0035 17.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDO69466.1 - 0.0018 18.7 0.8 0.019 15.3 0.8 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CDO69466.1 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDO69466.1 - 0.0055 16.1 0.0 0.026 13.9 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CDO69466.1 - 0.0068 16.0 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDO69466.1 - 0.0073 16.5 0.0 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDO69466.1 - 0.013 16.1 0.0 0.094 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CDO69466.1 - 0.015 15.0 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CDO69466.1 - 0.018 14.5 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 CDO69466.1 - 0.051 13.3 0.1 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDO69466.1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 CDO69466.1 - 0.098 12.7 0.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CDO69466.1 - 0.1 12.1 0.1 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 CDO69466.1 - 0.11 12.5 0.0 23 5.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CDO69466.1 - 0.12 11.6 0.1 0.6 9.4 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 CDO69466.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 CDO69466.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDO69466.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CDO69466.1 - 0.17 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CBFD_NFYB_HMF PF00808.23 CDO69467.1 - 9.4e-20 70.7 1.6 1.6e-19 69.9 1.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDO69467.1 - 8.4e-13 48.8 0.5 1.7e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 CDO69467.1 - 0.037 14.4 1.1 0.094 13.0 0.1 2.0 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Phage_holin_7_1 PF16081.5 CDO69467.1 - 0.06 13.5 0.5 0.091 12.9 0.5 1.3 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family TAF PF02969.17 CDO69467.1 - 0.13 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Cu-oxidase PF00394.22 CDO69469.1 - 2.7e-51 173.9 0.4 3.3e-47 160.6 0.1 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CDO69469.1 - 7.4e-39 132.4 2.3 2.8e-37 127.3 0.2 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CDO69469.1 - 5.8e-34 116.8 5.6 8.7e-32 109.7 0.3 3.8 3 1 0 3 3 3 2 Multicopper oxidase 2OG-FeII_Oxy PF03171.20 CDO69471.1 - 0.00049 20.5 0.0 0.00079 19.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CDO69472.1 - 3e-17 63.5 0.0 5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO69472.1 - 1.4e-13 51.2 0.0 3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CDO69473.1 - 1.5e-13 51.1 0.0 3.2e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CDO69473.1 - 2.6e-13 50.8 0.0 4.8e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Meth_synt_2 PF01717.18 CDO69475.1 - 1e-14 54.6 0.0 2.6e-10 40.1 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CDO69475.1 - 0.0034 16.9 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain zf-C2H2 PF00096.26 CDO69477.1 - 6.2e-06 26.4 20.0 0.0044 17.4 1.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO69477.1 - 0.0033 17.8 13.2 0.087 13.3 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDO69477.1 - 0.021 15.6 18.7 0.038 14.8 5.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CDO69477.1 - 0.093 13.2 8.4 0.22 12.0 3.6 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CDO69477.1 - 0.81 9.7 9.8 3.3 7.7 4.0 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 CDO69477.1 - 1.1 9.6 10.0 0.67 10.3 3.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding WD40 PF00400.32 CDO69478.1 - 2.9e-23 81.7 10.2 5.6e-05 23.8 1.3 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO69478.1 - 6.4e-07 29.6 0.7 1.8 8.9 0.4 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDO69478.1 - 0.014 15.3 0.1 0.4 10.5 0.0 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PNP_UDP_1 PF01048.20 CDO69479.1 - 1.1e-36 126.3 0.0 1.3e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF659 PF04937.15 CDO69480.1 - 1.2e-13 51.3 0.1 2.1e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Velvet PF11754.8 CDO69481.1 - 0.003 17.6 0.2 0.003 17.6 0.2 1.0 1 0 0 1 1 1 1 Velvet factor AIP3 PF03915.13 CDO69483.1 - 3.1e-22 79.3 7.9 3.5e-22 79.1 7.9 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 tRNA_bind_3 PF17176.4 CDO69483.1 - 0.03 14.6 0.0 0.033 14.5 0.0 1.1 1 0 0 1 1 1 0 tRNA-binding domain APG6_N PF17675.1 CDO69483.1 - 0.064 13.8 7.1 0.071 13.6 7.1 1.0 1 0 0 1 1 1 0 Apg6 coiled-coil region OmpH PF03938.14 CDO69483.1 - 0.07 13.5 3.2 0.082 13.2 3.2 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) KfrA_N PF11740.8 CDO69483.1 - 0.11 13.2 1.0 0.15 12.8 1.0 1.2 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term KDZ PF18758.1 CDO69485.1 - 2.7e-78 262.6 1.0 4.1e-78 262.0 0.1 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase SAM_KSR1 PF13543.6 CDO69485.1 - 0.076 13.2 0.6 0.18 11.9 0.6 1.6 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 CxC1 PF18802.1 CDO69485.1 - 0.085 13.0 0.1 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 CxC1 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 CDO69486.1 - 0.022 15.1 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Caulimovirus viroplasmin HMG_box PF00505.19 CDO69487.1 - 0.084 13.3 0.6 0.38 11.2 0.3 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box DEC-1_N PF04625.13 CDO69487.1 - 1.5 7.8 10.3 3.2 6.7 9.9 1.8 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region RT_RNaseH_2 PF17919.1 CDO69490.1 - 3.7e-10 39.7 0.0 7.6e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO69490.1 - 1.4e-09 38.2 0.0 3.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDO69490.1 - 1.8e-09 37.6 0.3 3.6e-09 36.6 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DUF4939 PF16297.5 CDO69492.1 - 1e-05 25.4 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 CDO69492.1 - 0.0022 18.2 0.0 0.013 15.7 0.0 2.2 1 1 2 3 3 3 1 Retrotransposon gag protein RVT_1 PF00078.27 CDO69493.1 - 5.2e-30 104.6 0.1 8.5e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDO69493.1 - 1.1e-16 60.7 0.0 2.4e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO69493.1 - 3.7e-07 30.4 0.0 6.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4407 PF14362.6 CDO69494.1 - 0.19 11.0 5.2 0.32 10.3 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 CDO69494.1 - 0.87 8.3 2.5 1.3 7.7 2.5 1.4 1 0 0 1 1 1 0 Presenilin ATP11 PF06644.11 CDO69494.1 - 1.6 8.5 7.4 2.7 7.7 7.4 1.3 1 0 0 1 1 1 0 ATP11 protein U79_P34 PF03064.16 CDO69494.1 - 2.1 7.7 10.6 4.1 6.7 10.6 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF755 PF05501.11 CDO69494.1 - 2.8 8.2 8.8 4.2 7.7 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MEF2_binding PF09047.10 CDO69495.1 - 0.032 14.1 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 MEF2 binding DUF659 PF04937.15 CDO69496.1 - 1.5e-13 50.9 0.1 2.5e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF1645 PF07816.11 CDO69496.1 - 0.74 10.4 4.2 0.39 11.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) K_oxygenase PF13434.6 CDO69497.1 - 2.2e-37 129.0 0.0 2.4e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AMP-binding PF00501.28 CDO69498.1 - 1.7e-86 290.5 0.0 2e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 CDO69499.1 - 4.7e-94 315.6 0.0 9.1e-35 120.2 0.0 3.2 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 CDO69499.1 - 1.3e-34 118.3 0.7 6.3e-10 39.3 0.1 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site Polyoma_coat2 PF00761.20 CDO69499.1 - 0.12 12.1 0.2 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Polyomavirus coat protein Transferase PF02458.15 CDO69499.1 - 0.13 10.9 0.0 26 3.3 0.0 3.3 4 0 0 4 4 4 0 Transferase family Inv-AAD PF18785.1 CDO69500.1 - 1.6e-27 95.9 0.0 4e-27 94.6 0.0 1.6 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 CDO69500.1 - 5.8e-15 55.0 0.0 9.6e-15 54.3 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDO69500.1 - 2.8e-06 27.1 0.1 0.0018 18.0 0.1 2.3 2 0 0 2 2 2 2 MafB19-like deaminase APOBEC_N PF08210.11 CDO69500.1 - 0.07 13.0 0.0 0.41 10.5 0.0 1.9 1 1 0 1 1 1 0 APOBEC-like N-terminal domain LpxK PF02606.14 CDO69500.1 - 0.21 10.6 0.0 1.5 7.8 0.0 1.9 1 1 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase SH2_2 PF14633.6 CDO69501.1 - 2.3e-78 262.5 0.2 2.3e-78 262.5 0.2 2.5 2 0 0 2 2 1 1 SH2 domain HHH_7 PF14635.6 CDO69501.1 - 1.7e-31 108.6 0.1 3.4e-31 107.7 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 CDO69501.1 - 3.1e-30 105.0 0.0 7.2e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 CDO69501.1 - 6.2e-28 97.5 0.0 1.7e-27 96.1 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 CDO69501.1 - 4.9e-20 71.9 25.3 4.9e-20 71.9 25.3 6.4 6 1 3 9 9 5 1 Acidic N-terminal SPT6 SH2 PF00017.24 CDO69501.1 - 3.7e-08 33.4 0.0 1.1e-06 28.6 0.0 3.1 3 0 0 3 3 3 1 SH2 domain HHH_9 PF17674.1 CDO69501.1 - 4.5e-06 27.5 0.4 1.7e-05 25.7 0.4 2.1 1 0 0 1 1 1 1 HHH domain HHH_3 PF12836.7 CDO69501.1 - 2.6e-05 24.4 0.1 6e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_N PF09371.10 CDO69501.1 - 0.038 13.7 1.6 0.093 12.4 0.0 2.4 3 0 0 3 3 3 0 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 CDO69501.1 - 0.18 12.3 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Tex protein YqgF-like domain Peptidase_A21 PF03566.13 CDO69501.1 - 0.6 8.3 2.6 1 7.6 2.6 1.2 1 0 0 1 1 1 0 Peptidase family A21 JmjC PF02373.22 CDO69502.1 - 8.7e-20 71.3 0.1 1.6e-19 70.4 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDO69502.1 - 1e-18 68.0 0.5 1.5e-18 67.5 0.5 1.2 1 0 0 1 1 1 1 Cupin-like domain Peptidase_M19 PF01244.21 CDO69503.1 - 9e-109 363.5 0.0 1.1e-108 363.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Arv1 PF04161.13 CDO69504.1 - 0.11 12.6 1.7 0.64 10.1 1.7 2.0 1 1 0 1 1 1 0 Arv1-like family DUF3742 PF12553.8 CDO69504.1 - 0.23 11.6 1.5 0.49 10.5 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) WD40 PF00400.32 CDO69505.1 - 2.1e-08 34.7 16.0 0.29 12.1 0.2 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO69505.1 - 2.5e-06 27.7 0.2 0.17 12.2 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 CDO69505.1 - 5.8 6.2 9.8 7.7 5.8 9.8 1.1 1 0 0 1 1 1 0 SDA1 SRP54 PF00448.22 CDO69506.1 - 5.7e-74 248.0 1.9 9.2e-74 247.3 1.9 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CDO69506.1 - 5.3e-32 110.4 2.4 5.2e-31 107.2 0.1 2.5 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 CDO69506.1 - 1.1e-18 67.1 3.0 2.4e-18 66.1 3.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 CDO69506.1 - 2.9e-05 24.3 0.1 6.9e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CDO69506.1 - 3.4e-05 23.5 0.3 9.2e-05 22.1 0.3 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CDO69506.1 - 0.00052 19.1 2.0 0.001 18.2 0.3 2.2 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 CDO69506.1 - 0.0015 19.0 1.3 0.0097 16.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 CDO69506.1 - 0.0019 18.3 0.1 0.0089 16.1 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fe-ADH PF00465.19 CDO69506.1 - 0.0073 15.2 0.4 0.016 14.1 0.0 1.7 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Zeta_toxin PF06414.12 CDO69506.1 - 0.01 15.1 0.1 0.024 13.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 CDO69506.1 - 0.014 15.2 2.3 0.027 14.2 0.4 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CDO69506.1 - 0.051 13.6 0.8 2.9 7.9 0.1 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit MipZ PF09140.11 CDO69506.1 - 0.061 12.6 0.1 1.9 7.7 0.1 2.3 1 1 0 1 1 1 0 ATPase MipZ AAA_31 PF13614.6 CDO69506.1 - 0.089 12.7 0.2 0.67 9.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain HTH_ParB PF17762.1 CDO69506.1 - 0.14 12.0 1.1 3.4 7.6 0.2 2.7 2 0 0 2 2 2 0 HTH domain found in ParB protein 6PF2K PF01591.18 CDO69506.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NTPase_1 PF03266.15 CDO69506.1 - 0.22 11.4 2.0 10 6.0 2.0 2.6 1 1 0 1 1 1 0 NTPase ArsA_ATPase PF02374.15 CDO69506.1 - 1.1 8.4 6.4 26 3.8 0.1 3.8 3 1 1 4 4 4 0 Anion-transporting ATPase DUF2884 PF11101.8 CDO69507.1 - 8.4 5.8 8.3 11 5.4 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) RRM_1 PF00076.22 CDO69508.1 - 7.5e-47 157.0 0.1 1.1e-19 70.0 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CDO69508.1 - 6.9e-27 93.4 3.5 7.1e-27 93.4 1.7 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain DEC-1_N PF04625.13 CDO69508.1 - 0.0027 16.8 17.3 0.011 14.8 0.5 2.2 2 0 0 2 2 2 2 DEC-1 protein, N-terminal region RRM_7 PF16367.5 CDO69508.1 - 0.004 17.3 0.0 1.9 8.6 0.0 3.5 3 1 0 3 3 3 1 RNA recognition motif DUF1494 PF07379.11 CDO69508.1 - 0.21 11.4 0.0 0.8 9.5 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1494) SCAMP PF04144.13 CDO69509.1 - 4.3e-54 183.5 7.7 5e-54 183.2 7.7 1.0 1 0 0 1 1 1 1 SCAMP family Nup54 PF13874.6 CDO69509.1 - 0.0098 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 DPBB_1 PF03330.18 CDO69510.1 - 1.8e-11 44.2 0.1 4.6e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CDO69510.1 - 6e-05 22.9 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Barwin family NOA36 PF06524.12 CDO69510.1 - 0.65 9.3 19.8 0.074 12.4 15.3 1.6 2 0 0 2 2 2 0 NOA36 protein Nop14 PF04147.12 CDO69510.1 - 0.67 8.1 11.3 0.86 7.7 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family NAD_binding_4 PF07993.12 CDO69511.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein ADK PF00406.22 CDO69512.1 - 4.2e-43 147.0 0.0 5.8e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDO69512.1 - 6e-19 68.8 0.0 1.3e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CDO69512.1 - 2.3e-14 53.1 0.0 3.7e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CDO69512.1 - 6.1e-06 26.8 0.0 1.7e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDO69512.1 - 0.0011 19.1 0.3 0.0049 17.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 CDO69512.1 - 0.028 14.3 0.2 0.059 13.3 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 CDO69512.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Methyltransf_PK PF05891.12 CDO69513.1 - 6.8e-51 172.9 0.0 4.6e-32 111.3 0.0 2.8 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CDO69513.1 - 1.4e-06 28.9 0.0 0.037 14.7 0.0 2.6 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CDO69513.1 - 0.00015 21.6 0.0 0.0003 20.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO69513.1 - 0.0004 21.0 0.1 0.28 11.8 0.0 2.5 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDO69513.1 - 0.00053 20.7 0.0 0.03 15.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Swi3 PF07962.12 CDO69514.1 - 8.6e-17 60.9 0.4 1.9e-15 56.6 0.4 2.3 1 1 0 1 1 1 1 Replication Fork Protection Component Swi3 TYA PF01021.19 CDO69516.1 - 0.16 12.3 0.5 0.16 12.3 0.5 2.0 2 0 0 2 2 2 0 TYA transposon protein zf-C2HE PF16278.5 CDO69517.1 - 1.1e-08 35.3 0.0 2.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 CDO69517.1 - 6.4e-08 33.1 3.7 2e-07 31.4 3.7 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2H2_4 PF13894.6 CDO69517.1 - 0.0048 17.6 0.3 0.0048 17.6 0.3 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 CDO69517.1 - 0.059 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon HIT PF01230.23 CDO69517.1 - 0.09 13.5 6.8 0.31 11.8 3.9 2.8 2 1 0 2 2 2 0 HIT domain ox_reductase_C PF08635.10 CDO69518.1 - 1e-74 248.8 0.3 1.5e-74 248.3 0.3 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 CDO69518.1 - 3.3e-22 79.6 0.0 6.3e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CDO69518.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain SKA2 PF16740.5 CDO69519.1 - 0.0029 17.4 2.1 0.0045 16.8 2.1 1.4 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Rx_N PF18052.1 CDO69519.1 - 0.017 15.4 4.2 0.027 14.8 4.2 1.2 1 0 0 1 1 1 0 Rx N-terminal domain DUF4472 PF14739.6 CDO69519.1 - 0.088 13.5 6.6 0.13 13.0 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) UPF0242 PF06785.11 CDO69519.1 - 0.15 12.2 6.4 0.2 11.8 6.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 CDO69519.1 - 0.29 11.1 6.7 0.38 10.7 6.7 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain V_ATPase_I PF01496.19 CDO69519.1 - 0.4 8.5 1.3 0.46 8.3 1.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 CDO69519.1 - 0.46 11.1 4.7 0.77 10.4 4.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA MCU PF04678.13 CDO69519.1 - 0.59 10.2 2.6 0.74 9.9 2.6 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF484 PF04340.12 CDO69519.1 - 0.63 9.7 6.2 0.85 9.3 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF484 RRP36 PF06102.12 CDO69519.1 - 6.4 6.7 11.4 9.5 6.2 11.4 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 PRIMA1 PF16101.5 CDO69520.1 - 0.6 10.2 7.8 0.86 9.6 6.7 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SAP PF02037.27 CDO69521.1 - 8.5e-10 38.2 0.2 3e-09 36.4 0.2 1.9 2 0 0 2 2 2 1 SAP domain DUF2315 PF10231.9 CDO69522.1 - 2e-31 108.6 0.0 3e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Apoptogenic protein 1 Nucleoporin_C PF03177.14 CDO69523.1 - 3.2e-76 257.3 0.5 2.4e-75 254.4 0.5 1.9 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 CDO69523.1 - 5.7e-15 55.0 0.0 8.1e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like DUF445 PF04286.12 CDO69523.1 - 0.48 10.2 3.7 4.3 7.1 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF445) PRCC PF10253.9 CDO69524.1 - 2.4e-37 129.8 2.4 2.4e-37 129.8 2.4 2.8 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Histone PF00125.24 CDO69525.1 - 3.1e-22 79.3 2.7 3.9e-22 79.0 2.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDO69525.1 - 1.2e-05 25.4 0.0 1.2e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CDO69525.1 - 0.0026 18.2 0.0 0.0049 17.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.11 CDO69525.1 - 0.019 14.6 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein YscO-like PF16789.5 CDO69525.1 - 0.035 14.1 0.2 0.044 13.8 0.2 1.2 1 0 0 1 1 1 0 YscO-like protein CENP-W PF15510.6 CDO69525.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein MaoC_dehydratas PF01575.19 CDO69526.1 - 0.00041 19.9 0.0 0.00072 19.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain Transglut_core PF01841.19 CDO69526.1 - 0.054 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily Aminotran_5 PF00266.19 CDO69528.1 - 1.3e-34 119.7 0.0 2.1e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V RabGAP-TBC PF00566.18 CDO69529.1 - 4.2e-44 150.8 6.2 2.8e-41 141.5 0.9 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 CDO69529.1 - 7e-10 38.6 0.0 5.9e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Rab-binding domain (RBD) Ribosomal_S21e PF01249.18 CDO69530.1 - 7.2e-39 131.8 0.0 8e-39 131.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF917 PF06032.12 CDO69530.1 - 0.0081 15.0 0.0 0.0081 15.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF917) PAP2 PF01569.21 CDO69531.1 - 5.5e-22 78.0 4.9 8.3e-22 77.4 4.9 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF5510 PF17629.2 CDO69531.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5510) PSDC PF12588.8 CDO69532.1 - 5.2e-51 172.3 0.0 8.4e-51 171.6 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 CDO69532.1 - 1.5e-36 125.8 0.0 2.1e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PPP4R2 PF09184.11 CDO69533.1 - 5.4e-27 95.1 0.2 1.3e-26 93.9 0.2 1.8 1 1 0 1 1 1 1 PPP4R2 SURF2 PF05477.11 CDO69534.1 - 1.7 8.3 12.4 2.6 7.7 12.4 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) MRI PF15325.6 CDO69534.1 - 4.9 8.3 9.4 9.8 7.3 9.4 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection CCDC106 PF15794.5 CDO69534.1 - 7.6 6.2 9.9 12 5.6 9.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SUI1 PF01253.22 CDO69535.1 - 2.1e-28 98.7 0.4 2.7e-28 98.3 0.4 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 SNRNP27 PF08648.12 CDO69536.1 - 1.6e-31 108.1 2.5 6.1e-31 106.3 1.8 2.0 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins GSH_synth_ATP PF03917.17 CDO69537.1 - 4.5e-132 440.4 0.0 5.2e-132 440.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CDO69537.1 - 1.8e-32 111.9 0.0 3e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Bac_rhodopsin PF01036.18 CDO69538.1 - 6.5e-35 120.7 17.6 7.9e-35 120.4 17.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein AAA PF00004.29 CDO69539.1 - 1.7e-44 151.5 0.1 5.6e-44 149.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CDO69539.1 - 1.4e-09 37.8 0.2 9.4e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CDO69539.1 - 1.2e-08 35.0 0.1 4.9e-08 33.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDO69539.1 - 5.6e-08 33.1 0.2 3e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CDO69539.1 - 6e-08 33.3 0.8 2.8e-05 24.5 0.0 3.1 3 1 0 4 4 3 1 AAA ATPase domain DUF815 PF05673.13 CDO69539.1 - 1.3e-06 27.8 0.1 3.1e-06 26.6 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CDO69539.1 - 1.3e-05 25.7 0.0 0.0012 19.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CDO69539.1 - 0.00012 22.0 0.9 0.0092 15.9 0.0 3.4 4 0 0 4 4 4 1 NTPase AAA_28 PF13521.6 CDO69539.1 - 0.0003 21.1 0.2 0.0011 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CDO69539.1 - 0.00037 20.5 0.0 0.0016 18.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CDO69539.1 - 0.00045 20.0 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CDO69539.1 - 0.00059 19.8 0.0 0.014 15.4 0.0 2.4 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_3 PF17862.1 CDO69539.1 - 0.00061 19.5 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CDO69539.1 - 0.00082 19.7 5.2 0.012 15.8 0.1 3.1 3 1 1 4 4 2 1 AAA domain RNA_helicase PF00910.22 CDO69539.1 - 0.002 18.5 0.0 0.0059 17.0 0.0 1.8 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.13 CDO69539.1 - 0.002 17.4 0.0 0.0044 16.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_30 PF13604.6 CDO69539.1 - 0.003 17.3 0.3 0.0082 15.9 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CDO69539.1 - 0.0032 17.0 0.1 0.021 14.3 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 CDO69539.1 - 0.0035 17.5 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDO69539.1 - 0.0076 16.0 0.2 0.022 14.5 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDO69539.1 - 0.008 15.6 0.1 0.019 14.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 CDO69539.1 - 0.0092 15.4 0.0 0.58 9.5 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein NACHT PF05729.12 CDO69539.1 - 0.0096 15.9 0.1 0.078 12.9 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_3 PF07726.11 CDO69539.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CDO69539.1 - 0.011 15.3 0.4 0.054 13.1 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 CDO69539.1 - 0.023 14.5 0.2 0.09 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CDO69539.1 - 0.023 14.4 0.5 0.055 13.2 0.1 1.9 2 1 0 2 2 1 0 AAA domain AAA_19 PF13245.6 CDO69539.1 - 0.04 14.2 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 CDO69539.1 - 0.064 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Bac_DnaA PF00308.18 CDO69539.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein T2SSE PF00437.20 CDO69539.1 - 0.076 12.1 0.0 0.17 10.9 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 CDO69539.1 - 0.089 12.5 0.2 1.1 9.0 0.0 2.7 3 1 0 3 3 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 CDO69539.1 - 0.097 12.6 1.4 0.65 9.9 0.0 2.7 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CDO69539.1 - 0.12 12.9 0.4 0.62 10.6 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.17 CDO69539.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 cobW PF02492.19 CDO69539.1 - 0.15 11.6 0.1 0.37 10.4 0.0 1.7 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 CDO69539.1 - 0.2 11.0 1.9 0.46 9.8 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.6 CDO69539.1 - 5.3 7.5 0.0 5.3 7.5 0.0 2.4 2 0 0 2 2 1 0 AAA domain P5CR_dimer PF14748.6 CDO69540.1 - 1.2e-38 131.5 3.3 1.2e-38 131.5 3.3 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CDO69540.1 - 0.0019 18.7 0.0 0.0074 16.9 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Glyco_tran_28_C PF04101.16 CDO69541.1 - 3.3e-27 95.5 0.0 3.9e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain NAC PF01849.18 CDO69543.1 - 2e-22 78.9 0.0 5.3e-22 77.6 0.0 1.7 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.6 CDO69543.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain SelP_N PF04592.14 CDO69543.1 - 5.1 6.4 11.6 9.8 5.5 11.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1264 PF06884.11 CDO69544.1 - 5.2e-51 172.6 2.9 4.8e-28 97.9 1.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1264) Abhydrolase_3 PF07859.13 CDO69545.1 - 1.3e-32 113.3 0.0 1.8e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDO69545.1 - 1.8e-13 50.1 0.0 2.4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 CDO69545.1 - 0.0014 18.2 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CDO69545.1 - 0.047 14.3 1.2 0.081 13.5 1.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 CDO69545.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 CDO69546.1 - 8.3e-32 110.8 0.0 1.2e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDO69546.1 - 3.7e-11 42.5 0.0 5.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 CDO69546.1 - 5.8e-05 22.1 0.0 8.9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CDO69546.1 - 0.0028 17.2 0.0 0.57 9.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hamartin PF04388.12 CDO69547.1 - 0.00041 19.2 1.7 0.00041 19.2 1.7 3.1 2 1 0 3 3 3 2 Hamartin protein HALZ PF02183.18 CDO69547.1 - 1.1 9.6 6.3 0.38 11.0 1.1 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper KELK PF15796.5 CDO69547.1 - 1.5 9.4 27.5 0.3 11.6 4.1 3.9 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase THOC7 PF05615.13 CDO69547.1 - 3.9 7.8 24.5 8.1 6.7 2.1 3.5 3 0 0 3 3 3 0 Tho complex subunit 7 HSP90 PF00183.18 CDO69548.1 - 1.2e-232 773.5 30.4 1.5e-232 773.1 30.4 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CDO69548.1 - 1e-15 58.2 0.0 2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDO69548.1 - 3e-10 40.0 0.1 3e-10 40.0 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 CDO69548.1 - 0.034 14.1 0.3 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN DUF2052 PF09747.9 CDO69548.1 - 4.5 7.4 17.4 4.3 7.4 11.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Methyltransf_11 PF08241.12 CDO69549.1 - 2.1e-14 53.9 0.0 3.9e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO69549.1 - 1.2e-11 45.1 0.0 3.3e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO69549.1 - 6e-07 30.1 0.0 2e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO69549.1 - 1.3e-05 25.1 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 CDO69549.1 - 0.022 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_28 PF02636.17 CDO69549.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RVP_2 PF08284.11 CDO69550.1 - 2.7e-07 30.4 0.0 5.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDO69550.1 - 1.6e-06 28.7 0.0 2.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDO69550.1 - 0.0024 18.4 0.0 0.0039 17.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 CDO69550.1 - 0.0052 16.3 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase Retrotrans_gag PF03732.17 CDO69551.1 - 3e-14 53.0 0.0 6.5e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO69551.1 - 4.6e-09 36.1 0.0 1.3e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) Retrotran_gag_2 PF14223.6 CDO69551.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RAP1 PF07218.11 CDO69551.1 - 1.7 6.9 5.4 2.2 6.5 5.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RT_RNaseH PF17917.1 CDO69552.1 - 1.3e-33 115.4 1.2 3.6e-33 114.0 0.1 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO69552.1 - 1.4e-27 95.7 0.3 3.9e-27 94.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO69552.1 - 2.8e-13 49.9 0.2 4.7e-13 49.2 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3425 PF11905.8 CDO69552.1 - 0.013 15.4 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) Get5_C PF18514.1 CDO69552.1 - 0.2 11.4 0.5 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Get5 C-terminal domain rve PF00665.26 CDO69553.1 - 8.7e-12 45.3 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDO69553.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF5089 PF17002.5 CDO69554.1 - 0.0086 16.0 1.2 0.0086 16.0 1.2 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF5089) RasGAP_C PF03836.15 CDO69554.1 - 0.012 15.8 0.5 0.012 15.8 0.5 1.1 1 0 0 1 1 1 0 RasGAP C-terminus COG2 PF06148.11 CDO69554.1 - 0.022 14.8 0.4 0.025 14.7 0.4 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Methyltransf_1N PF02870.15 CDO69554.1 - 0.04 14.7 0.4 0.052 14.4 0.4 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain FlxA PF14282.6 CDO69554.1 - 0.049 13.6 0.1 0.054 13.5 0.1 1.1 1 0 0 1 1 1 0 FlxA-like protein CENP-Q PF13094.6 CDO69554.1 - 0.16 12.2 6.7 0.19 11.9 6.7 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Coilin_N PF15862.5 CDO69555.1 - 0.14 12.0 7.3 0.22 11.3 7.3 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF4019 PF13211.6 CDO69555.1 - 0.29 11.6 4.2 0.39 11.1 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) Eapp_C PF10238.9 CDO69555.1 - 1.2 9.2 7.3 2.6 8.1 7.3 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein Zn_clus PF00172.18 CDO69555.1 - 2.6 8.3 8.6 3.6 7.8 6.6 2.1 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Presenilin PF01080.17 CDO69555.1 - 7.5 5.2 6.4 8.3 5.1 6.4 1.0 1 0 0 1 1 1 0 Presenilin 2Fe-2S_thioredx PF01257.19 CDO69556.1 - 0.22 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin RT_RNaseH_2 PF17919.1 CDO69557.1 - 4.7e-09 36.2 0.0 8.9e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO69557.1 - 0.00017 21.8 0.0 0.00037 20.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDO69557.1 - 0.0086 16.6 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO69557.1 - 0.015 15.9 0.0 0.03 15.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 CDO69557.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.26 CDO69558.1 - 2.4e-09 37.4 0.0 4.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 CDO69558.1 - 1.8e-08 34.3 0.0 2.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO69558.1 - 8.4e-08 32.5 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDO69558.1 - 0.0025 17.9 0.3 0.0051 16.9 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain LRR_4 PF12799.7 CDO69562.1 - 0.15 12.5 2.2 5.9 7.5 0.1 3.8 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 CDO69563.1 - 0.0018 18.1 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 CDO69563.1 - 0.0071 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like domain DUF2009 PF09418.10 CDO69564.1 - 1.4e-211 703.5 0.0 1.6e-211 703.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) PCI PF01399.27 CDO69565.1 - 7e-07 29.7 0.0 6.1e-06 26.7 0.0 2.4 2 1 0 2 2 2 1 PCI domain HTH_28 PF13518.6 CDO69565.1 - 0.0036 17.4 0.0 0.94 9.7 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 CDO69565.1 - 0.0065 16.2 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 2 Homeodomain-like domain YdaS_antitoxin PF15943.5 CDO69565.1 - 0.12 12.3 0.1 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SelP_N PF04592.14 CDO69567.1 - 0.22 10.9 8.8 0.22 10.9 8.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SPX PF03105.19 CDO69567.1 - 0.82 9.5 6.2 0.91 9.4 6.2 1.0 1 0 0 1 1 1 0 SPX domain ORMDL PF04061.14 CDO69569.1 - 3.6e-45 153.1 1.9 4.7e-45 152.7 1.9 1.1 1 0 0 1 1 1 1 ORMDL family Staygreen PF12638.7 CDO69569.1 - 0.053 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Staygreen protein THF_DHG_CYH PF00763.23 CDO69570.1 - 2.7e-21 76.0 0.0 4.1e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CDO69570.1 - 6.1e-11 41.9 0.1 1.4e-10 40.8 0.1 1.5 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain WD40 PF00400.32 CDO69571.1 - 2.9e-20 72.2 10.1 0.0006 20.6 0.0 6.5 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO69571.1 - 7.9e-12 45.3 0.0 0.0012 19.1 0.0 3.7 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Arb1 PF09692.10 CDO69572.1 - 8e-12 45.0 0.0 3.8e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Pinin_SDK_N PF04697.13 CDO69572.1 - 0.022 15.4 0.2 0.19 12.3 0.1 2.2 2 0 0 2 2 2 0 pinin/SDK conserved region AAA_16 PF13191.6 CDO69574.1 - 2.4e-17 63.9 0.0 5.1e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ORC4_C PF14629.6 CDO69574.1 - 1.9e-16 60.1 0.0 1.8e-10 40.6 0.0 2.4 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 4 C-terminus AAA_5 PF07728.14 CDO69574.1 - 0.0006 19.8 0.0 0.004 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 CDO69574.1 - 0.0016 18.4 0.0 0.74 9.7 0.0 2.3 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 CDO69574.1 - 0.0022 18.4 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDO69574.1 - 0.003 17.1 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 CDO69574.1 - 0.0036 17.5 0.0 0.0089 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDO69574.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CDO69574.1 - 0.02 15.2 0.0 0.066 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CDO69574.1 - 0.068 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_19 PF13245.6 CDO69574.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDO69574.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AT_hook PF02178.19 CDO69574.1 - 1.9 8.6 8.5 0.11 12.4 1.9 2.6 2 0 0 2 2 2 0 AT hook motif TSC22 PF01166.18 CDO69575.1 - 1.1 9.6 8.4 0.2 12.0 0.4 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family adh_short PF00106.25 CDO69576.1 - 1.1e-42 145.7 0.4 1.9e-42 145.0 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69576.1 - 1.3e-40 139.4 0.2 3.5e-40 138.0 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO69576.1 - 6.1e-11 42.6 0.6 1.8e-10 41.0 0.1 1.9 1 1 1 2 2 2 1 KR domain Pyr_redox PF00070.27 CDO69576.1 - 7.5e-05 23.2 0.6 0.0019 18.8 0.1 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CDO69576.1 - 0.0022 17.9 0.1 0.0045 16.9 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 CDO69576.1 - 0.012 14.9 0.1 0.023 14.0 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_tran_WecB PF03808.13 CDO69576.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family YjeF_N PF03853.15 CDO69576.1 - 0.024 14.5 0.1 0.06 13.2 0.1 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus ApbA PF02558.16 CDO69576.1 - 0.031 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 CDO69576.1 - 0.035 13.6 0.2 0.091 12.2 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 CDO69576.1 - 0.036 13.4 0.3 0.06 12.6 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1776 PF08643.10 CDO69576.1 - 0.038 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 CDO69576.1 - 0.038 14.0 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 CDO69576.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase eIF2A PF08662.11 CDO69577.1 - 3.2e-40 138.1 0.4 9.2e-37 126.8 0.0 4.5 3 3 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CDO69577.1 - 6e-09 35.6 0.0 1.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CDO69577.1 - 0.0047 17.8 1.6 51 5.0 0.0 5.8 6 0 0 6 6 6 0 WD domain, G-beta repeat DUF4998 PF16389.5 CDO69577.1 - 0.12 12.0 0.0 1.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DBINO PF13892.6 CDO69577.1 - 0.58 10.5 10.0 3.9 7.9 7.7 2.3 2 0 0 2 2 2 0 DNA-binding domain RRM_1 PF00076.22 CDO69578.1 - 6e-33 112.5 0.0 7.2e-16 57.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDO69578.1 - 1.7e-05 24.8 0.0 5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 CDO69578.1 - 0.00048 20.1 0.0 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CDO69578.1 - 0.0014 18.7 0.0 0.8 9.9 0.1 3.4 3 0 0 3 3 3 1 RNA recognition motif Red1 PF07964.11 CDO69578.1 - 7.8 4.6 4.9 12 4.0 4.9 1.1 1 0 0 1 1 1 0 Rec10 / Red1 RasGAP PF00616.19 CDO69579.1 - 6.2e-23 81.6 0.0 1.3e-18 67.5 0.0 3.0 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 CDO69579.1 - 6.7e-06 26.3 0.1 1.8e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 CDO69579.1 - 0.0002 21.3 0.1 0.0013 18.7 0.1 2.5 1 0 0 1 1 1 1 Cell morphogenesis C-terminal Band_7 PF01145.25 CDO69580.1 - 9.5e-23 81.1 4.0 1.4e-22 80.6 4.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.25 CDO69581.1 - 1.9e-21 76.7 0.0 6.5e-19 68.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69581.1 - 2.3e-07 30.3 0.0 1.4e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO69581.1 - 0.0035 17.3 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CDO69581.1 - 0.035 13.7 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 P2 PF07194.11 CDO69581.1 - 0.12 12.4 2.1 0.27 11.3 2.1 1.5 1 0 0 1 1 1 0 P2 response regulator binding domain NOA36 PF06524.12 CDO69581.1 - 2.5 7.4 4.3 4.2 6.6 4.3 1.3 1 0 0 1 1 1 0 NOA36 protein UCH PF00443.29 CDO69582.1 - 1.2e-24 87.2 0.0 3.1e-24 85.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDO69582.1 - 0.0011 18.7 0.4 0.0042 16.7 0.4 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CREPT PF16566.5 CDO69582.1 - 0.46 10.6 3.0 0.33 11.1 0.8 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour BTB PF00651.31 CDO69583.1 - 7.9e-12 45.4 0.0 1.2e-05 25.5 0.0 2.8 3 0 0 3 3 3 2 BTB/POZ domain BRD4_CDT PF17105.5 CDO69584.1 - 0.36 10.4 4.1 1 9.0 4.1 1.8 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Aldedh PF00171.22 CDO69585.1 - 3.2e-106 355.6 0.0 3.9e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_isomerase PF00160.21 CDO69586.1 - 3.9e-39 134.4 0.0 5.8e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CDO69586.1 - 6.6e-16 57.9 0.0 1.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.31 CDO69586.1 - 2.8e-09 37.2 0.0 4.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RRP7 PF12923.7 CDO69588.1 - 4e-18 65.7 3.2 4e-18 65.7 3.2 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 CDO69588.1 - 1.6e-09 37.8 0.0 4.7e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 CDO69588.1 - 4.9e-06 26.3 0.0 0.00016 21.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribonuc_red_sm PF00268.21 CDO69589.1 - 0.064 12.7 1.0 0.089 12.2 1.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain Pro-kuma_activ PF09286.11 CDO69591.1 - 5.7e-37 127.2 0.0 1.2e-36 126.1 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Abhydrolase_1 PF00561.20 CDO69593.1 - 4.9e-22 78.8 0.3 2.9e-19 69.7 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO69593.1 - 1.3e-18 68.5 0.8 1.8e-18 67.9 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO69593.1 - 1.8e-16 60.2 0.0 4.3e-16 58.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 CDO69593.1 - 7e-06 25.9 0.1 0.047 13.5 0.0 2.9 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 CDO69593.1 - 6.1e-05 23.1 0.0 9.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 CDO69593.1 - 8.1e-05 22.3 0.2 0.012 15.2 0.5 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family Lipase_2 PF01674.18 CDO69593.1 - 0.0015 18.1 0.0 0.0034 16.9 0.0 1.5 2 0 0 2 2 2 1 Lipase (class 2) DUF2048 PF09752.9 CDO69593.1 - 0.0026 16.9 0.2 1.7 7.7 0.0 2.1 2 0 0 2 2 2 2 Abhydrolase domain containing 18 Abhydrolase_3 PF07859.13 CDO69593.1 - 0.0046 16.8 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 CDO69593.1 - 0.049 12.3 0.0 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 Ndr family BAAT_C PF08840.11 CDO69593.1 - 0.053 13.4 0.0 0.62 10.0 0.1 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.12 CDO69593.1 - 0.086 11.6 0.2 0.13 11.0 0.2 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 UPF0227 PF05728.12 CDO69593.1 - 0.2 11.6 0.0 8.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) ATG22 PF11700.8 CDO69596.1 - 1.1e-110 370.6 16.7 1.5e-110 370.1 16.7 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 CDO69596.1 - 1.8e-12 46.9 32.9 2.6e-08 33.2 12.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SHOCT PF09851.9 CDO69596.1 - 0.002 17.8 2.5 0.0032 17.1 2.5 1.3 1 0 0 1 1 1 1 Short C-terminal domain VbhA PF18495.1 CDO69596.1 - 0.092 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Antitoxin VbhA MCPVI PF02993.14 CDO69598.1 - 0.089 12.6 0.5 0.11 12.3 0.5 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Pkinase_fungal PF17667.1 CDO69599.1 - 2.1e-58 198.0 0.0 5.9e-58 196.6 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO69600.1 - 1.6e-54 185.3 0.0 3.3e-53 180.9 0.0 2.1 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CDO69600.1 - 0.021 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain RFC1 PF08519.12 CDO69600.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Foie-gras_1 PF11817.8 CDO69602.1 - 4.2e-30 105.2 1.8 1e-27 97.3 0.4 2.9 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 CDO69602.1 - 1.5e-17 63.6 0.0 1.1e-14 54.1 0.0 2.1 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi TPR_12 PF13424.6 CDO69602.1 - 0.00031 21.0 0.5 0.013 15.8 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat Gryzun-like PF12742.7 CDO69602.1 - 0.0045 17.0 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TPR_10 PF13374.6 CDO69602.1 - 0.0081 16.0 0.2 0.081 12.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDO69602.1 - 0.012 15.4 0.0 0.05 13.4 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDO69602.1 - 0.054 13.6 3.0 0.12 12.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Trs65 PF12735.7 CDO69602.1 - 0.068 12.6 0.0 5.9 6.2 0.0 2.5 2 0 0 2 2 2 0 TRAPP trafficking subunit Trs65 TPR_7 PF13176.6 CDO69602.1 - 0.086 12.9 0.1 0.6 10.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDO69602.1 - 0.16 12.3 0.0 0.58 10.5 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Amidase PF01425.21 CDO69603.1 - 3.6e-31 108.6 0.1 5.4e-31 108.0 0.1 1.1 1 0 0 1 1 1 1 Amidase Acetyltransf_1 PF00583.25 CDO69606.1 - 8.8e-07 29.2 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO69606.1 - 0.00032 21.1 0.0 0.00054 20.3 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDO69606.1 - 0.0055 16.6 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CDO69606.1 - 0.02 15.5 0.0 0.025 15.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDO69606.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cyclin_N PF00134.23 CDO69607.1 - 4.4e-07 29.7 0.0 5.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CDO69607.1 - 1.7e-06 28.5 0.0 2.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin Pkinase_fungal PF17667.1 CDO69611.1 - 0.0028 16.5 0.0 0.003 16.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Ribonucleas_3_3 PF14622.6 CDO69612.1 - 0.00017 21.7 0.1 0.0016 18.6 0.1 2.0 1 1 0 1 1 1 1 Ribonuclease-III-like RT_RNaseH_2 PF17919.1 CDO69613.1 - 3.8e-32 110.3 0.0 9.9e-32 109.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO69613.1 - 2e-31 108.4 0.2 5.2e-31 107.0 0.2 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO69613.1 - 2.1e-27 96.1 0.1 3.6e-27 95.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDO69613.1 - 2.7e-19 69.0 2.8 7.1e-19 67.7 0.5 2.6 2 0 0 2 2 2 1 Integrase zinc binding domain Chromo PF00385.24 CDO69613.1 - 1e-14 54.1 0.2 2.4e-14 52.9 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 CDO69613.1 - 2.7e-10 40.7 0.0 6.6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO69613.1 - 2.5e-08 34.4 0.1 5.9e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDO69613.1 - 4.2e-08 33.1 0.0 7.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 CDO69613.1 - 9.5e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease SF3a60_bindingd PF12108.8 CDO69613.1 - 5.9 6.9 7.1 5.1 7.1 0.3 3.1 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Retrotran_gag_2 PF14223.6 CDO69614.1 - 7.5e-21 74.3 0.0 1.1e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO69614.1 - 0.01 15.9 2.2 0.01 15.9 2.2 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDO69614.1 - 0.15 11.8 0.4 0.6 9.9 0.4 1.9 2 0 0 2 2 2 0 Zinc knuckle rve PF00665.26 CDO69615.1 - 0.0033 17.6 0.0 0.0055 16.9 0.0 1.4 2 0 0 2 2 2 1 Integrase core domain RVT_2 PF07727.14 CDO69616.1 - 2e-65 220.8 0.0 2.9e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CCDC53 PF10152.9 CDO69616.1 - 0.97 9.8 5.3 2 8.9 5.3 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DDE_3 PF13358.6 CDO69617.1 - 1.6e-10 40.9 0.0 5e-10 39.3 0.0 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CDO69617.1 - 1.1e-06 28.8 0.0 5.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Transposase Methyltransf_11 PF08241.12 CDO69617.1 - 0.11 13.1 0.2 2.2 9.0 0.1 3.0 3 1 1 4 4 4 0 Methyltransferase domain zinc_ribbon_6 PF14599.6 CDO69618.1 - 0.025 14.6 0.1 0.057 13.4 0.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon Ribosomal_S27e PF01667.17 CDO69618.1 - 0.035 13.8 0.6 0.091 12.5 0.3 1.7 2 0 0 2 2 2 0 Ribosomal protein S27 DUF2015 PF09435.10 CDO69619.1 - 1.2e-31 108.8 0.0 1.3e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Epimerase PF01370.21 CDO69620.1 - 5.4e-17 62.1 0.0 9.4e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO69620.1 - 1.9e-12 46.8 0.0 2.8e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CDO69620.1 - 2.5e-12 46.5 0.0 6.2e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 CDO69620.1 - 2.7e-09 37.2 0.1 4.4e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CDO69620.1 - 3.9e-09 36.4 0.0 5.6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CDO69620.1 - 3.5e-05 23.5 0.1 5.4e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 CDO69620.1 - 0.00043 19.8 0.1 0.00097 18.6 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO69620.1 - 0.0047 16.9 0.1 0.035 14.0 0.1 2.1 1 1 0 1 1 1 1 KR domain F-box PF00646.33 CDO69621.1 - 1.5e-05 24.8 0.1 3.1e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 CDO69621.1 - 5e-05 23.3 0.0 9.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain F-box-like PF12937.7 CDO69621.1 - 0.00016 21.5 0.1 0.00039 20.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.6 CDO69621.1 - 0.00079 19.1 1.2 0.026 14.2 0.0 2.7 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.17 CDO69621.1 - 0.01 15.9 0.2 0.036 14.2 0.2 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDO69621.1 - 0.03 14.1 0.1 0.077 12.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box_4 PF15966.5 CDO69621.1 - 0.046 13.6 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 F-box TPR_14 PF13428.6 CDO69621.1 - 0.1 13.4 2.8 0.11 13.4 0.4 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDO69621.1 - 0.2 11.7 3.4 0.85 9.8 0.2 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDO69621.1 - 0.23 11.4 1.1 4 7.4 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1977 PF09320.11 CDO69622.1 - 3.1e-27 94.9 0.1 6.7e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 CDO69622.1 - 2.5e-25 88.4 0.5 7.2e-25 86.9 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 CDO69622.1 - 0.073 13.2 0.1 0.34 11.1 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 CDO69623.1 - 3.3e-09 37.2 6.0 0.81 10.7 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Plavaka PF18759.1 CDO69624.1 - 2.7e-26 92.6 0.0 5e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase DUF3487 PF11990.8 CDO69626.1 - 1.4 8.8 5.2 0.84 9.5 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) RED_N PF07808.13 CDO69627.1 - 5.2e-19 68.8 4.3 5.2e-19 68.8 4.3 2.3 3 0 0 3 3 3 1 RED-like protein N-terminal region IF4E PF01652.18 CDO69629.1 - 7.8e-55 185.0 0.0 1e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Kei1 PF08552.11 CDO69630.1 - 4.3e-52 176.8 6.6 6e-52 176.3 6.6 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 ALF PF03752.13 CDO69630.1 - 0.033 14.2 0.3 0.11 12.5 0.3 1.9 1 0 0 1 1 1 0 Short repeats of unknown function ACPS PF01648.20 CDO69631.1 - 0.0016 18.5 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PQ-loop PF04193.14 CDO69633.1 - 4.9e-33 112.7 4.4 2.1e-17 62.6 0.3 3.0 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 CDO69633.1 - 1.5e-06 29.1 4.0 3.8e-05 24.5 0.5 2.5 2 1 1 3 3 3 1 ER lumen protein retaining receptor MtN3_slv PF03083.16 CDO69633.1 - 0.011 15.7 6.9 0.72 9.9 0.5 2.9 2 2 1 3 3 3 0 Sugar efflux transporter for intercellular exchange TMEM100 PF16311.5 CDO69633.1 - 0.13 11.8 0.8 0.59 9.7 0.1 2.4 3 0 0 3 3 3 0 Transmembrane protein 100 PgaD PF13994.6 CDO69633.1 - 0.39 10.8 3.8 0.51 10.4 0.0 2.5 1 1 2 3 3 3 0 PgaD-like protein DUF3087 PF11286.8 CDO69633.1 - 2.7 7.4 4.6 0.4 10.1 0.2 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3087) Clr2_transil PF16761.5 CDO69634.1 - 2.5e-26 92.3 0.9 4.7e-26 91.4 0.9 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 CDO69634.1 - 4.4e-08 34.0 0.0 2.8e-05 24.9 0.0 3.5 3 0 0 3 3 3 2 Transcription-silencing protein Clr2 KAR9 PF08580.10 CDO69635.1 - 1e-18 67.3 46.2 1e-18 67.3 46.2 4.5 3 1 1 4 4 4 2 Yeast cortical protein KAR9 COG2 PF06148.11 CDO69635.1 - 0.17 12.0 0.4 0.51 10.4 0.4 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Allexi_40kDa PF05549.11 CDO69635.1 - 0.31 10.5 1.3 0.96 8.9 1.3 1.9 1 0 0 1 1 1 0 Allexivirus 40kDa protein GARP PF16731.5 CDO69635.1 - 0.35 10.5 3.4 1.3 8.7 3.5 1.9 1 1 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma FUSC PF04632.12 CDO69635.1 - 0.39 9.2 2.0 0.59 8.6 2.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Myb_DNA-bind_6 PF13921.6 CDO69635.1 - 0.52 10.6 3.2 2.5 8.4 0.3 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Muted PF14942.6 CDO69635.1 - 0.53 10.6 1.9 1.3 9.4 0.4 2.3 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein TPR_19 PF14559.6 CDO69636.1 - 5.6e-08 33.2 0.5 5.6e-08 33.2 0.5 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDO69636.1 - 5.2e-07 30.2 1.5 5.2e-07 30.2 1.5 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDO69636.1 - 3.3e-06 26.8 1.6 0.0027 17.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDO69636.1 - 3.6e-06 27.0 0.9 1.2e-05 25.4 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDO69636.1 - 0.0002 21.9 19.1 0.0096 16.7 0.0 5.1 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDO69636.1 - 0.00024 20.9 0.3 0.00024 20.9 0.3 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDO69636.1 - 0.001 19.1 0.4 0.001 19.1 0.4 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDO69636.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDO69636.1 - 0.0035 17.3 1.4 0.033 14.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDO69636.1 - 0.0048 17.0 0.1 0.031 14.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDO69636.1 - 0.0072 16.0 0.2 0.64 9.7 0.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_20 PF14561.6 CDO69636.1 - 0.017 15.5 1.1 0.017 15.5 1.1 2.7 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDO69636.1 - 0.018 15.3 0.9 0.069 13.4 0.2 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat BTAD PF03704.17 CDO69636.1 - 0.018 15.5 2.6 0.023 15.1 0.2 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain HemY_N PF07219.13 CDO69636.1 - 0.043 14.0 1.4 0.11 12.7 0.6 2.0 1 1 0 1 1 1 0 HemY protein N-terminus HrpB1_HrpK PF09613.10 CDO69636.1 - 0.05 13.2 0.8 3.7 7.2 0.2 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 CDO69636.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CDO69636.1 - 0.3 11.8 0.1 0.3 11.8 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Lactamase_B_2 PF12706.7 CDO69637.1 - 4.6e-19 68.7 1.5 8.8e-19 67.8 0.9 1.7 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDO69637.1 - 1.9e-14 53.9 1.2 3.6e-14 53.0 1.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDO69637.1 - 0.14 12.1 7.6 0.043 13.8 3.8 2.1 2 1 1 3 3 3 0 Metallo-beta-lactamase superfamily TPT PF03151.16 CDO69638.1 - 1.5e-55 188.6 19.3 1.8e-55 188.3 19.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CDO69638.1 - 5.6e-10 38.9 18.6 7.5e-10 38.5 18.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDO69638.1 - 8.4e-09 35.7 32.0 8.9e-06 25.9 12.9 2.6 2 1 0 2 2 2 2 EamA-like transporter family DUF4126 PF13548.6 CDO69638.1 - 1 9.0 12.3 0.14 11.8 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4126) UDPGT PF00201.18 CDO69639.1 - 4.6e-18 65.3 0.1 7.5e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO69639.1 - 0.00037 20.5 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PQ-loop PF04193.14 CDO69640.1 - 1.5e-12 47.1 2.0 2.2e-12 46.6 0.5 2.0 2 1 0 2 2 2 1 PQ loop repeat ER_lumen_recept PF00810.18 CDO69640.1 - 0.0019 19.0 0.5 0.0049 17.7 0.2 1.7 1 1 1 2 2 2 1 ER lumen protein retaining receptor OSTbeta PF15048.6 CDO69640.1 - 0.066 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Peptidase_U4 PF03419.13 CDO69640.1 - 0.15 11.3 3.1 0.23 10.7 3.1 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA CitMHS PF03600.16 CDO69640.1 - 0.51 9.5 3.9 8 5.6 0.2 2.1 2 0 0 2 2 2 0 Citrate transporter DUF1771 PF08590.10 CDO69641.1 - 1e-06 29.0 9.2 2.7e-06 27.7 9.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 CDO69641.1 - 0.0022 17.7 0.4 0.14 11.9 0.0 3.3 4 0 0 4 4 4 1 CUE domain RLL PF10036.9 CDO69641.1 - 0.026 14.4 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein UBA PF00627.31 CDO69641.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Aldedh PF00171.22 CDO69642.1 - 3.1e-97 326.0 1.1 3.8e-97 325.7 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PBP_like PF12727.7 CDO69642.1 - 0.11 11.6 0.2 0.21 10.7 0.2 1.5 1 0 0 1 1 1 0 PBP superfamily domain Aldedh PF00171.22 CDO69643.1 - 2.6e-92 309.8 5.4 1.8e-78 264.1 2.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 CDO69643.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) T7SS_ESX_EspC PF10824.8 CDO69643.1 - 1.2 9.7 5.7 0.35 11.4 0.4 2.5 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Acetyltransf_1 PF00583.25 CDO69644.1 - 0.00012 22.3 0.0 0.00034 20.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDO69644.1 - 0.00028 20.8 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDO69644.1 - 0.0011 19.3 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SIR2 PF02146.17 CDO69645.1 - 7.7e-46 156.2 0.0 5.8e-45 153.4 0.0 2.3 1 1 0 1 1 1 1 Sir2 family DUF592 PF04574.13 CDO69645.1 - 2.7e-07 30.5 0.1 3.8e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 CDO69645.1 - 0.0066 16.2 0.4 4 7.2 0.2 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain CutC PF03932.14 CDO69645.1 - 0.013 15.0 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 CutC family Sigma70_ner PF04546.13 CDO69645.1 - 2.7 7.9 7.4 5.5 6.8 7.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF357 PF04010.13 CDO69647.1 - 0.22 11.6 4.0 0.88 9.7 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF357) UPF0242 PF06785.11 CDO69647.1 - 0.49 10.5 6.0 1.3 9.1 6.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus U1snRNP70_N PF12220.8 CDO69647.1 - 2.7 8.7 8.8 0.52 11.0 0.1 3.7 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Apolipoprotein PF01442.18 CDO69647.1 - 4.1 7.2 32.7 0.37 10.7 1.0 4.6 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain Chromo_shadow PF01393.19 CDO69648.1 - 6.8e-16 58.1 0.8 1e-13 51.2 0.2 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 CDO69648.1 - 5.2e-12 45.5 1.1 1e-11 44.6 0.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Hamartin PF04388.12 CDO69648.1 - 2.1 6.9 11.2 0.06 12.0 3.4 1.9 2 0 0 2 2 2 0 Hamartin protein AT_hook PF02178.19 CDO69648.1 - 4.1 7.6 11.7 0.52 10.4 3.8 3.6 3 0 0 3 3 3 0 AT hook motif RRM_1 PF00076.22 CDO69649.1 - 1.2e-14 53.9 0.0 1.8e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDO69649.1 - 0.0018 18.3 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 CDO69649.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDO69649.1 - 0.17 11.9 0.2 0.3 11.1 0.2 1.5 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-MYND PF01753.18 CDO69650.1 - 1.6e-05 24.9 9.9 0.0016 18.5 1.1 2.5 2 0 0 2 2 2 2 MYND finger DUF3846 PF12957.7 CDO69650.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) CAP_N PF01213.19 CDO69651.1 - 0.04 13.4 3.8 0.073 12.5 3.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PAG PF15347.6 CDO69651.1 - 0.065 12.2 6.3 0.084 11.9 6.3 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Pox_Ag35 PF03286.14 CDO69651.1 - 3.3 7.4 5.8 4.5 7.0 5.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pro-kuma_activ PF09286.11 CDO69652.1 - 4.9e-37 127.4 0.0 1.8e-36 125.6 0.0 2.0 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO69652.1 - 0.006 15.9 1.3 0.023 14.0 0.7 2.3 1 1 1 2 2 2 1 Subtilase family Glyco_hydro_127 PF07944.12 CDO69653.1 - 1.1e-17 63.8 0.0 6.9e-16 57.8 0.0 2.4 2 1 1 3 3 3 2 Beta-L-arabinofuranosidase, GH127 Sds3 PF08598.11 CDO69654.1 - 3.3e-07 30.5 0.3 5.9e-07 29.7 0.3 1.4 1 1 0 1 1 1 1 Sds3-like DLH PF01738.18 CDO69655.1 - 3.7e-23 82.2 0.0 4.2e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Acyl_transf_2 PF02273.15 CDO69655.1 - 0.0062 15.8 0.0 0.0077 15.5 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase TPR_2 PF07719.17 CDO69657.1 - 1.2e-08 34.4 0.0 4.1e-05 23.4 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDO69657.1 - 5.7e-06 25.9 0.1 0.002 17.9 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO69657.1 - 0.00016 22.1 0.0 0.00027 21.4 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDO69657.1 - 0.00077 19.5 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDO69657.1 - 0.0008 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CDO69657.1 - 0.005 17.6 0.1 0.026 15.3 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO69657.1 - 0.0098 16.1 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CDO69657.1 - 0.069 13.1 0.2 5.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.29 CDO69658.1 - 1.5e-47 161.6 0.0 3e-47 160.6 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO69658.1 - 6.9e-31 106.9 0.0 2.6e-30 105.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO69658.1 - 0.075 13.0 0.0 0.28 11.1 0.0 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit GT87 PF09594.10 CDO69659.1 - 0.0021 17.8 0.4 0.0034 17.2 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 87 TFIIA PF03153.13 CDO69659.1 - 0.15 12.0 38.3 0.21 11.6 38.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF383 PF04063.14 CDO69660.1 - 1.5e-61 207.4 0.0 5.1e-61 205.7 0.0 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CDO69660.1 - 1e-21 76.5 1.1 2.5e-21 75.3 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT PF02985.22 CDO69660.1 - 0.13 12.6 0.0 0.69 10.3 0.0 2.4 1 0 0 1 1 1 0 HEAT repeat RTC4 PF14474.6 CDO69661.1 - 7.5e-25 87.4 0.0 1.7e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 RTC4-like domain SPATIAL PF15256.6 CDO69661.1 - 5.3 7.3 10.2 2 8.7 5.4 2.9 2 0 0 2 2 2 0 SPATIAL DLH PF01738.18 CDO69663.1 - 1.5e-25 90.0 0.0 1.8e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CDO69663.1 - 0.085 12.5 0.1 7.7 6.1 0.1 2.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Ferrochelatase PF00762.19 CDO69663.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Ferrochelatase PTS_2-RNA PF01885.16 CDO69664.1 - 7.8e-21 74.9 0.2 1e-20 74.5 0.2 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ribosomal_L23 PF00276.20 CDO69665.1 - 2e-09 37.6 0.0 3.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 DLH PF01738.18 CDO69666.1 - 3.6e-23 82.3 0.0 4.1e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Zn_clus PF00172.18 CDO69667.1 - 4.6e-09 36.3 10.2 8.3e-09 35.4 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 CDO69669.1 - 1.3e-66 225.2 3.6 1.6e-66 224.9 3.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO69669.1 - 1.8e-13 51.1 0.9 4e-06 27.2 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDO69669.1 - 0.024 14.4 0.0 0.35 10.6 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Pkinase PF00069.25 CDO69670.1 - 1.2e-22 80.5 0.0 7.8e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69670.1 - 1e-06 28.3 0.0 0.03 13.6 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 CDO69670.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_16 PF10294.9 CDO69672.1 - 2.9e-28 98.8 0.0 4e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CDO69672.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO69672.1 - 0.044 14.5 0.0 0.13 13.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDO69672.1 - 0.14 12.9 0.0 0.28 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rhomboid PF01694.22 CDO69673.1 - 3.8e-18 65.9 16.0 3e-17 63.0 13.0 2.9 2 1 0 2 2 2 1 Rhomboid family SHS2_Rpb7-N PF03876.17 CDO69674.1 - 2.2e-15 56.8 0.0 3.6e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CDO69674.1 - 1.9e-11 44.1 0.1 3.4e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 CDO69674.1 - 0.088 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 adh_short_C2 PF13561.6 CDO69675.1 - 4.7e-59 199.8 0.1 5.9e-59 199.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO69675.1 - 2.2e-47 161.1 0.6 2.6e-47 160.8 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO69675.1 - 2.5e-12 47.1 0.4 4.4e-12 46.3 0.4 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO69675.1 - 0.00015 21.4 0.2 0.00031 20.3 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CDO69675.1 - 0.00025 20.5 0.0 0.00037 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Flavodoxin_1 PF00258.25 CDO69675.1 - 0.0033 17.6 0.0 0.45 10.7 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin Polysacc_synt_2 PF02719.15 CDO69675.1 - 0.0056 15.9 0.3 0.0067 15.6 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AdoHcyase_NAD PF00670.21 CDO69675.1 - 0.0063 16.6 0.1 0.0093 16.1 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 CDO69675.1 - 0.053 12.8 1.3 0.081 12.2 0.9 1.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HEM4 PF02602.15 CDO69675.1 - 0.073 12.4 0.2 0.22 10.8 0.2 1.8 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD ADH_zinc_N PF00107.26 CDO69675.1 - 0.077 13.0 0.1 2.8 8.0 0.1 2.5 1 1 0 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CDO69675.1 - 0.11 11.9 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Flavodoxin_5 PF12724.7 CDO69675.1 - 0.15 12.3 0.4 22 5.3 0.0 2.9 3 0 0 3 3 3 0 Flavodoxin domain Sortilin-Vps10 PF15902.5 CDO69676.1 - 1.6e-292 969.9 0.0 3.8e-149 497.3 0.0 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CDO69676.1 - 3e-95 317.3 13.0 7.1e-49 166.4 3.9 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CDO69676.1 - 1.8e-10 39.2 39.0 1 9.7 0.4 12.2 11 0 0 11 11 11 6 BNR/Asp-box repeat BNR_2 PF13088.6 CDO69676.1 - 2.6e-05 23.6 2.5 0.42 9.9 0.0 5.7 7 1 0 7 7 7 2 BNR repeat-like domain CHB_HEX_C PF03174.13 CDO69676.1 - 8.8e-05 22.4 1.7 0.23 11.4 0.0 6.0 8 0 0 8 8 8 1 Chitobiase/beta-hexosaminidase C-terminal domain PSII_BNR PF14870.6 CDO69676.1 - 0.0094 15.2 0.6 7.1 5.8 0.0 3.9 3 1 0 3 3 3 2 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.16 CDO69676.1 - 0.018 15.1 0.6 23 5.0 0.0 5.3 6 1 1 7 7 7 0 Mo-co oxidoreductase dimerisation domain Pro-kuma_activ PF09286.11 CDO69677.1 - 1.6e-32 112.7 0.0 2.5e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO69677.1 - 6.2e-07 29.0 0.0 1.3e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Subtilase family Ran_BP1 PF00638.18 CDO69678.1 - 2.4e-17 63.3 0.0 4.3e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain YjbR PF04237.13 CDO69678.1 - 0.14 12.7 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 YjbR TPX2 PF06886.11 CDO69678.1 - 4.1 7.7 9.5 0.093 13.0 1.7 2.3 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Rxt3 PF08642.10 CDO69680.1 - 0.00018 22.3 0.0 0.00018 22.3 0.0 3.4 3 1 0 3 3 3 1 Histone deacetylation protein Rxt3 PI_PP_I PF18363.1 CDO69681.1 - 0.0002 21.5 1.9 0.17 12.0 0.0 3.8 3 2 1 4 4 4 1 Phosphoinositide phosphatase insertion domain DUF2730 PF10805.8 CDO69681.1 - 0.0002 21.4 3.2 0.012 15.7 0.4 3.0 3 0 0 3 3 2 1 Protein of unknown function (DUF2730) DUF3450 PF11932.8 CDO69681.1 - 0.0025 17.1 3.6 0.0039 16.5 0.1 2.7 2 1 0 3 3 3 1 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 CDO69681.1 - 0.0029 17.6 9.8 0.022 14.8 3.0 2.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 CDO69681.1 - 0.0031 17.7 16.0 2 8.7 0.1 4.6 3 2 1 4 4 4 1 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 CDO69681.1 - 0.0055 17.2 10.5 0.27 11.8 2.7 2.9 3 0 0 3 3 3 2 Apg6 coiled-coil region NPV_P10 PF05531.12 CDO69681.1 - 0.0077 16.7 11.8 3.2 8.3 1.7 4.7 3 3 1 4 4 4 1 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 CDO69681.1 - 0.01 15.4 5.0 0.041 13.4 0.0 2.8 3 1 0 3 3 3 0 Golgin subfamily A member 5 USP8_interact PF08941.10 CDO69681.1 - 0.036 13.9 1.0 0.085 12.7 0.2 2.0 2 0 0 2 2 2 0 USP8 interacting DUF2383 PF09537.10 CDO69681.1 - 0.038 14.3 0.5 0.99 9.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) Snapin_Pallidin PF14712.6 CDO69681.1 - 0.053 13.9 9.8 0.16 12.4 0.9 3.3 3 1 0 3 3 3 0 Snapin/Pallidin Filament PF00038.21 CDO69681.1 - 0.073 12.6 10.1 0.23 11.0 0.2 3.0 3 0 0 3 3 3 0 Intermediate filament protein ZapB PF06005.12 CDO69681.1 - 0.074 13.5 10.6 0.099 13.1 1.8 3.6 3 1 0 3 3 3 0 Cell division protein ZapB TRPM_tetra PF16519.5 CDO69681.1 - 0.076 13.1 7.3 1.8 8.7 0.9 3.7 3 0 0 3 3 3 0 Tetramerisation domain of TRPM DUF4618 PF15397.6 CDO69681.1 - 0.11 11.9 5.2 0.31 10.4 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Laminin_II PF06009.12 CDO69681.1 - 0.12 12.4 14.3 1.4 9.0 0.1 3.9 3 2 1 4 4 4 0 Laminin Domain II DUF1664 PF07889.12 CDO69681.1 - 0.14 12.2 11.7 13 5.8 0.2 4.0 3 2 0 3 3 3 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 CDO69681.1 - 0.14 12.4 6.5 5.8 7.2 0.7 3.5 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 PqqD PF05402.12 CDO69681.1 - 0.14 12.5 1.0 5.7 7.3 0.0 3.3 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) Baculo_PEP_C PF04513.12 CDO69681.1 - 0.15 12.1 9.1 0.15 12.1 1.5 3.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4140 PF13600.6 CDO69681.1 - 0.15 12.5 12.0 0.36 11.3 0.2 4.0 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) BLOC1_2 PF10046.9 CDO69681.1 - 0.21 11.9 11.9 0.73 10.2 2.6 3.9 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PI3K_P85_iSH2 PF16454.5 CDO69681.1 - 0.4 10.3 7.4 1.3 8.6 4.8 3.2 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FlaC_arch PF05377.11 CDO69681.1 - 0.47 10.9 7.9 7 7.1 0.1 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) PRKG1_interact PF15898.5 CDO69681.1 - 0.48 11.3 11.1 1.2 10.1 0.3 3.8 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain GAS PF13851.6 CDO69681.1 - 0.56 9.5 11.8 1.5 8.2 1.4 3.3 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Leu_zip PF15294.6 CDO69681.1 - 0.59 9.6 11.3 0.044 13.3 1.4 2.8 3 0 0 3 3 3 0 Leucine zipper FlxA PF14282.6 CDO69681.1 - 0.76 9.8 8.3 1.1 9.2 0.7 3.5 4 0 0 4 4 4 0 FlxA-like protein COG2 PF06148.11 CDO69681.1 - 1.3 9.1 9.4 1.7 8.7 0.1 4.1 4 1 1 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Fez1 PF06818.15 CDO69681.1 - 1.5 9.2 8.7 4 7.8 4.9 2.6 1 1 1 2 2 2 0 Fez1 JIP_LZII PF16471.5 CDO69681.1 - 1.5 9.0 11.5 0.15 12.2 2.1 3.6 4 0 0 4 4 4 0 JNK-interacting protein leucine zipper II Retrotrans_gag PF03732.17 CDO69681.1 - 1.7 9.0 5.3 21 5.5 0.1 3.6 2 2 1 3 3 3 0 Retrotransposon gag protein Rootletin PF15035.6 CDO69681.1 - 1.9 8.5 11.7 16 5.4 3.0 3.6 2 2 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SesA PF17107.5 CDO69681.1 - 2.7 8.2 8.3 0.45 10.7 0.3 2.9 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sec34 PF04136.15 CDO69681.1 - 2.8 7.8 12.7 5.9 6.8 0.1 3.9 3 3 0 3 3 3 0 Sec34-like family Phage_GPO PF05929.11 CDO69681.1 - 2.8 7.5 8.1 6.8 6.2 0.4 3.0 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase LPP PF04728.13 CDO69681.1 - 2.9 8.3 13.8 31 5.1 0.0 5.1 5 0 0 5 5 5 0 Lipoprotein leucine-zipper Sec2p PF06428.11 CDO69681.1 - 3.6 7.6 13.0 0.18 11.8 0.4 3.4 3 2 0 3 3 3 0 GDP/GTP exchange factor Sec2p CRR7 PF12095.8 CDO69681.1 - 4.1 7.9 6.5 34 5.0 0.1 4.0 3 1 1 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 Uso1_p115_C PF04871.13 CDO69681.1 - 4.6 7.6 10.1 0.4 11.0 2.4 3.0 3 1 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Mod_r PF07200.13 CDO69681.1 - 5.3 7.2 14.1 2.7 8.1 0.4 3.8 2 2 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SSFA2_C PF14723.6 CDO69681.1 - 7.7 6.4 7.0 2 8.3 0.7 2.6 3 0 0 3 3 2 0 Sperm-specific antigen 2 C-terminus KASH_CCD PF14662.6 CDO69681.1 - 8 6.2 15.5 0.064 13.1 4.0 2.9 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH Epsilon_antitox PF08998.11 CDO69682.1 - 0.0059 16.8 1.1 2.4 8.5 0.3 2.8 1 1 1 2 2 2 2 Bacterial epsilon antitoxin NEMO PF11577.8 CDO69682.1 - 0.018 15.0 1.8 0.092 12.8 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO PI_PP_I PF18363.1 CDO69682.1 - 0.023 14.9 0.0 0.2 11.9 0.0 2.4 1 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Rootletin PF15035.6 CDO69682.1 - 0.053 13.5 1.8 0.098 12.7 1.8 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ApoLp-III PF07464.11 CDO69682.1 - 0.065 13.3 5.1 0.18 11.9 1.1 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) GP41 PF00517.17 CDO69682.1 - 0.086 12.7 0.1 2.4 8.0 0.0 2.4 2 1 0 2 2 2 0 Retroviral envelope protein GldM_N PF12081.8 CDO69682.1 - 0.38 10.8 4.1 0.48 10.5 0.2 2.4 2 1 0 2 2 2 0 GldM N-terminal domain BLOC1_2 PF10046.9 CDO69682.1 - 1.1 9.6 7.9 12 6.2 0.0 3.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4692 PF15763.5 CDO69683.1 - 3.7 8.0 6.6 9.1 6.7 6.6 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) HSF_DNA-bind PF00447.17 CDO69686.1 - 1.6e-32 111.9 2.7 3.1e-32 111.1 2.7 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Vezatin PF12632.7 CDO69688.1 - 0.032 13.6 1.1 0.45 9.8 0.3 2.2 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes PAXIP1_C PF15364.6 CDO69688.1 - 0.073 13.4 0.9 0.17 12.2 0.9 1.6 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein LisH PF08513.11 CDO69689.1 - 0.00016 21.5 0.1 0.00027 20.8 0.1 1.4 1 0 0 1 1 1 1 LisH FAM91_C PF14648.6 CDO69689.1 - 0.1 11.4 0.5 0.18 10.6 0.5 1.3 1 0 0 1 1 1 0 FAM91 C-terminus CDC45 PF02724.14 CDO69689.1 - 2.6 6.3 10.4 15 3.7 8.8 2.0 2 0 0 2 2 2 0 CDC45-like protein NARP1 PF12569.8 CDO69689.1 - 5.3 5.8 11.5 13 4.6 11.5 1.6 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 START PF01852.19 CDO69690.1 - 3.1e-24 85.5 0.4 3.3e-11 43.0 0.0 3.8 4 0 0 4 4 4 3 START domain SHD1 PF03983.12 CDO69690.1 - 0.09 12.6 0.3 0.29 11.0 0.3 1.8 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 Phos_pyr_kin PF08543.12 CDO69691.1 - 3.9e-12 46.1 0.0 7.7e-12 45.1 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CDO69691.1 - 5.8e-05 22.5 0.4 0.00017 21.0 0.0 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Gram_pos_anchor PF00746.21 CDO69692.1 - 0.23 11.4 2.3 0.67 10.0 2.3 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Adeno_E3_CR2 PF02439.15 CDO69693.1 - 0.082 12.7 1.6 0.13 12.0 1.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 VSP PF03302.13 CDO69693.1 - 0.22 10.3 0.4 0.3 9.9 0.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein FUSC_2 PF13515.6 CDO69695.1 - 6.1e-18 65.2 9.1 6.1e-18 65.2 9.1 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CDO69695.1 - 1.5e-09 38.1 0.3 9.8e-09 35.4 0.1 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 CDO69695.1 - 5e-07 28.7 13.6 3.9e-05 22.4 7.6 2.7 2 1 0 2 2 2 2 Fusaric acid resistance protein family ALMT PF11744.8 CDO69695.1 - 1.1e-05 24.5 9.1 0.00037 19.5 5.6 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter SAB PF04382.13 CDO69695.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 SAB domain FUSC-like PF12805.7 CDO69695.1 - 0.31 10.1 14.4 0.097 11.7 1.3 3.4 3 1 1 4 4 4 0 FUSC-like inner membrane protein yccS Cu-oxidase PF00394.22 CDO69696.1 - 8.6e-50 168.9 0.1 1.3e-45 155.4 0.1 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CDO69696.1 - 1e-39 135.2 1.0 5.2e-36 123.3 0.1 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 CDO69696.1 - 1.5e-37 128.4 7.1 2.2e-34 118.1 0.1 4.0 3 1 0 3 3 3 3 Multicopper oxidase GlgX_C PF18390.1 CDO69696.1 - 0.11 12.3 0.0 0.85 9.5 0.0 2.4 2 0 0 2 2 2 0 Glycogen debranching enzyme C-terminal domain RNA_pol_Rbc25 PF08292.12 CDO69697.1 - 3.9e-31 108.0 0.0 6e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Mito_carr PF00153.27 CDO69698.1 - 2.1e-50 168.6 1.0 1.3e-23 82.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Actin PF00022.19 CDO69699.1 - 8.2e-116 387.0 0.0 3.7e-115 384.8 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CDO69699.1 - 0.0065 15.3 0.0 0.018 13.9 0.0 1.6 1 1 0 1 1 1 1 MreB/Mbl protein zf-HC5HC2H_2 PF13832.6 CDO69700.1 - 1e-29 102.9 9.8 1.2e-28 99.5 5.0 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 CDO69700.1 - 1.5e-24 87.2 0.2 1.5e-24 87.2 0.2 3.6 4 0 0 4 4 4 1 Enhancer of polycomb-like Bromodomain PF00439.25 CDO69700.1 - 1.7e-20 72.9 0.2 3.3e-20 72.0 0.2 1.5 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.6 CDO69700.1 - 3.1e-20 72.2 11.6 3.7e-20 72.0 2.6 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CDO69700.1 - 1.8e-16 59.4 8.1 3.9e-15 55.1 2.6 2.5 2 0 0 2 2 2 2 PHD-finger PWWP PF00855.17 CDO69700.1 - 1.4e-13 51.1 0.3 1.4e-13 51.1 0.3 2.1 2 0 0 2 2 1 1 PWWP domain PHD PF00628.29 CDO69700.1 - 2.5e-10 40.1 5.7 2.5e-10 40.1 5.7 2.8 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 CDO69700.1 - 0.0031 17.2 0.8 0.0031 17.2 0.8 2.3 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.16 CDO69700.1 - 0.0081 16.4 0.6 0.0081 16.4 0.6 2.7 3 0 0 3 3 2 1 FYVE-type zinc finger C1_1 PF00130.22 CDO69700.1 - 0.014 15.2 0.4 0.014 15.2 0.4 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4611 PF15387.6 CDO69700.1 - 0.015 15.5 1.0 0.42 10.9 0.1 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Prok-RING_1 PF14446.6 CDO69700.1 - 7.9 6.5 15.7 0.29 11.1 3.5 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 DNA_pol_delta_4 PF04081.13 CDO69701.1 - 1.3e-31 109.7 0.8 2.4e-31 108.8 0.8 1.6 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Gp_dh_C PF02800.20 CDO69701.1 - 0.16 11.5 0.6 0.25 10.9 0.3 1.6 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Mt_ATP-synt_B PF05405.14 CDO69702.1 - 2.4e-44 150.8 10.7 3e-44 150.5 10.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Cortex-I_coil PF09304.10 CDO69702.1 - 0.17 12.1 6.1 0.23 11.7 5.7 1.5 1 1 0 1 1 1 0 Cortexillin I, coiled coil Peptidase_C10 PF01640.17 CDO69702.1 - 0.21 11.9 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase C10 family SLATT_1 PF18181.1 CDO69702.1 - 2 8.3 6.6 1.3 8.9 4.7 1.7 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Methyltransf_16 PF10294.9 CDO69703.1 - 7.5e-14 51.8 0.0 1.6e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 CDO69703.1 - 0.0014 19.3 0.0 0.0041 17.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDO69703.1 - 0.037 13.6 0.0 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.12 CDO69703.1 - 0.042 14.6 0.0 0.2 12.4 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 CDO69703.1 - 0.16 11.7 0.0 0.37 10.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CDO69703.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1658 PF07871.11 CDO69703.1 - 0.32 11.0 2.1 2.2 8.4 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Lipase_GDSL_2 PF13472.6 CDO69704.1 - 1.3e-06 29.0 0.0 1.7e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CDO69704.1 - 0.056 13.4 0.0 0.075 13.0 0.0 1.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Methyltransf_25 PF13649.6 CDO69705.1 - 0.0024 18.6 0.0 0.13 12.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO69705.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DPPIV_N PF00930.21 CDO69707.1 - 3.9e-72 243.0 0.1 6.1e-72 242.3 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CDO69707.1 - 7.3e-49 166.1 0.8 1.1e-48 165.5 0.8 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CDO69707.1 - 6.5e-06 25.9 3.0 2.4e-05 24.1 1.8 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 CDO69707.1 - 0.00051 19.8 0.2 0.00089 19.0 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO69707.1 - 0.0015 19.2 1.4 0.0015 19.2 1.4 2.8 2 2 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDO69707.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 CDO69707.1 - 0.1 11.2 0.0 0.19 10.3 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Dynamin_M PF01031.20 CDO69709.1 - 1.7e-94 316.2 0.1 6.5e-94 314.3 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CDO69709.1 - 2.6e-54 183.8 0.0 4.9e-54 182.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CDO69709.1 - 7.7e-30 102.9 1.1 7e-29 99.8 0.7 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CDO69709.1 - 0.0009 19.3 0.0 0.0072 16.4 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase SPX PF03105.19 CDO69709.1 - 8.3 6.2 6.6 16 5.3 6.6 1.4 1 0 0 1 1 1 0 SPX domain BCS1_N PF08740.11 CDO69710.1 - 3.8e-18 66.1 6.2 4.9e-18 65.8 0.2 3.3 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 CDO69710.1 - 1.1e-14 55.0 0.0 3e-13 50.4 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDO69710.1 - 0.0023 18.4 0.1 0.0023 18.4 0.1 3.3 3 2 0 3 3 2 1 AAA ATPase domain AAA_11 PF13086.6 CDO69710.1 - 0.0038 17.0 8.4 2.9 7.6 9.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CDO69710.1 - 0.0055 16.9 0.0 0.0055 16.9 0.0 2.4 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 CDO69710.1 - 0.011 15.5 1.8 0.012 15.4 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DDRGK PF09756.9 CDO69710.1 - 0.03 13.9 15.9 3.7 7.1 19.9 2.3 2 0 0 2 2 2 0 DDRGK domain YlbE PF14003.6 CDO69710.1 - 0.054 14.0 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 YlbE-like protein RuvB_N PF05496.12 CDO69710.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain XRN_M PF17846.1 CDO69710.1 - 0.083 11.8 7.6 0.13 11.2 7.6 1.3 1 0 0 1 1 1 0 Xrn1 helical domain NACHT PF05729.12 CDO69710.1 - 0.099 12.6 0.1 0.31 10.9 0.1 1.9 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CDO69710.1 - 0.16 12.2 0.0 0.52 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CDO69710.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDO69710.1 - 0.22 11.0 0.0 0.49 9.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region CAF1 PF04857.20 CDO69710.1 - 0.29 10.2 3.9 19 4.3 0.0 2.3 2 0 0 2 2 2 0 CAF1 family ribonuclease CAF-1_p150 PF11600.8 CDO69710.1 - 0.3 10.8 31.6 0.76 9.5 31.6 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_18 PF13238.6 CDO69710.1 - 0.49 10.9 0.0 0.49 10.9 0.0 3.0 3 1 0 3 3 2 0 AAA domain TMEM214 PF10151.9 CDO69710.1 - 4 5.8 10.4 5.7 5.3 10.4 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator AAA_23 PF13476.6 CDO69710.1 - 4.8 7.6 17.7 12 6.3 12.3 2.8 3 0 0 3 3 3 0 AAA domain Presenilin PF01080.17 CDO69710.1 - 9.4 4.9 14.8 28 3.3 14.8 1.9 1 0 0 1 1 1 0 Presenilin SYS1 PF09801.9 CDO69711.1 - 7e-20 71.7 2.0 6.5e-18 65.3 1.8 2.0 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network zf-MYND PF01753.18 CDO69713.1 - 0.00033 20.7 11.2 0.00066 19.7 11.2 1.5 1 0 0 1 1 1 1 MYND finger AAA_2 PF07724.14 CDO69714.1 - 3.6e-46 157.4 0.0 8.1e-44 149.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDO69714.1 - 2.3e-33 114.2 0.5 2.3e-33 114.2 0.5 2.9 3 0 0 3 3 2 1 AAA lid domain AAA PF00004.29 CDO69714.1 - 4.6e-20 72.4 1.1 1.3e-10 41.8 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDO69714.1 - 1.2e-18 67.0 0.2 1.2e-18 67.0 0.2 2.5 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CDO69714.1 - 1.3e-16 60.9 0.0 8.8e-11 42.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDO69714.1 - 1.7e-09 38.3 11.0 5.4e-05 23.6 0.0 5.0 4 2 1 6 6 4 2 AAA ATPase domain AAA_22 PF13401.6 CDO69714.1 - 3.8e-09 36.9 1.3 0.0018 18.6 0.0 3.8 3 1 0 3 3 2 2 AAA domain DnaJ PF00226.31 CDO69714.1 - 1.5e-08 34.6 0.0 4.1e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Sigma54_activat PF00158.26 CDO69714.1 - 7.7e-08 32.2 0.0 5.4e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 CDO69714.1 - 3.4e-06 26.9 0.4 0.11 12.2 0.0 3.4 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.6 CDO69714.1 - 4.2e-06 27.3 0.4 0.12 12.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 CDO69714.1 - 6.6e-06 25.7 0.2 0.18 11.2 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CDO69714.1 - 9.6e-06 25.9 3.6 0.3 11.3 0.0 5.2 4 1 1 5 5 5 1 AAA domain AAA_14 PF13173.6 CDO69714.1 - 1.7e-05 24.9 0.0 0.056 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CDO69714.1 - 1.8e-05 24.4 0.0 0.05 13.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 CDO69714.1 - 2.2e-05 24.3 0.3 0.046 13.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain RuvB_N PF05496.12 CDO69714.1 - 0.00011 21.9 2.5 0.92 9.2 0.0 3.9 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 CDO69714.1 - 0.00013 22.5 5.0 0.19 12.3 0.0 3.9 3 1 0 3 3 3 1 ABC transporter RNA_helicase PF00910.22 CDO69714.1 - 0.00047 20.5 0.0 1.7 9.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Roc PF08477.13 CDO69714.1 - 0.00054 20.2 0.0 0.94 9.7 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CDO69714.1 - 0.0012 18.7 1.5 1.9 8.3 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase ATPase_2 PF01637.18 CDO69714.1 - 0.0016 18.4 10.3 0.17 11.8 0.0 4.6 3 2 1 5 5 5 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 CDO69714.1 - 0.0038 16.9 0.0 2.7 7.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain TsaE PF02367.17 CDO69714.1 - 0.0067 16.4 0.0 6.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDO69714.1 - 0.0069 16.3 0.1 0.9 9.4 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.6 CDO69714.1 - 0.0097 16.3 0.1 0.32 11.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 CDO69714.1 - 0.011 15.6 0.0 4.9 6.9 0.0 2.7 2 0 0 2 2 2 0 Bacterial dnaA protein NTPase_1 PF03266.15 CDO69714.1 - 0.013 15.5 0.2 6 6.7 0.0 3.6 4 0 0 4 4 2 0 NTPase SRP54 PF00448.22 CDO69714.1 - 0.017 14.8 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 CDO69714.1 - 0.017 14.9 7.4 2.8 7.7 0.0 3.9 4 0 0 4 4 4 0 AAA domain ResIII PF04851.15 CDO69714.1 - 0.035 14.1 0.2 18 5.3 0.0 3.3 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.17 CDO69714.1 - 0.039 13.7 0.3 2.5 7.8 0.0 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 CDO69714.1 - 0.065 12.8 1.4 3.7 7.1 0.0 3.5 3 1 0 3 3 2 0 AAA domain AAA_30 PF13604.6 CDO69714.1 - 0.066 12.9 3.8 0.75 9.5 0.0 3.4 3 1 0 3 3 2 0 AAA domain DNA_pol3_delta2 PF13177.6 CDO69714.1 - 0.066 13.0 0.2 0.7 9.7 0.0 2.6 2 1 0 2 2 1 0 DNA polymerase III, delta subunit AAA_21 PF13304.6 CDO69714.1 - 0.072 12.9 3.2 5.9 6.6 0.0 3.7 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDO69714.1 - 0.081 12.6 1.1 37 3.8 0.3 3.1 3 0 0 3 3 3 0 AAA ATPase domain Pox_A_type_inc PF04508.12 CDO69714.1 - 0.087 12.7 1.2 1.9 8.5 0.6 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat AAA_3 PF07726.11 CDO69714.1 - 0.089 12.7 0.0 31 4.5 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 CDO69714.1 - 0.14 11.9 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CDO69714.1 - 0.21 11.7 1.0 28 4.8 0.0 3.5 3 1 0 3 3 3 0 50S ribosome-binding GTPase AAA_23 PF13476.6 CDO69714.1 - 0.22 12.0 0.0 0.22 12.0 0.0 4.3 4 1 0 4 4 2 0 AAA domain UPF0242 PF06785.11 CDO69714.1 - 1.5 8.9 11.6 6.9 6.7 10.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_33 PF13671.6 CDO69714.1 - 2.9 8.0 0.0 2.9 8.0 0.0 3.8 5 0 0 5 5 2 0 AAA domain Atg14 PF10186.9 CDO69714.1 - 5.7 5.9 7.9 12 4.9 7.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_17 PF13207.6 CDO69714.1 - 5.9 7.3 8.5 17 5.8 0.0 3.7 4 0 0 4 4 2 0 AAA domain Hydrophobin PF01185.18 CDO69715.1 - 6.4e-20 71.6 9.6 7.5e-20 71.3 9.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CoatB PF10389.9 CDO69715.1 - 3.4 7.6 9.1 0.32 10.9 2.8 2.3 2 1 1 3 3 3 0 Bacteriophage coat protein B zf-C2H2 PF00096.26 CDO69718.1 - 2.1e-07 31.0 20.4 0.0022 18.3 0.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO69718.1 - 4.5e-06 26.8 12.9 0.0036 17.7 0.2 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDO69718.1 - 0.00015 22.3 18.2 0.064 14.1 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDO69718.1 - 0.28 11.2 5.9 8.4 6.5 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 CDO69718.1 - 4.8 7.9 9.0 5 7.8 3.3 2.8 1 1 2 3 3 3 0 FOXP coiled-coil domain DUF2415 PF10313.9 CDO69719.1 - 4e-08 33.0 0.1 1.1e-07 31.6 0.1 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) PD40 PF07676.12 CDO69719.1 - 0.038 13.9 0.1 0.96 9.5 0.1 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CDO69719.1 - 0.13 11.2 0.0 0.47 9.4 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 CDO69719.1 - 0.17 12.8 3.3 16 6.5 0.0 4.2 6 0 0 6 6 6 0 WD domain, G-beta repeat Lon_C PF05362.13 CDO69721.1 - 3.3e-68 229.3 0.2 5.8e-68 228.5 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CDO69721.1 - 3.3e-37 128.4 0.1 8.8e-37 127.0 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CDO69721.1 - 1.2e-21 77.5 0.0 3.3e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDO69721.1 - 6e-08 32.8 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDO69721.1 - 1.3e-05 25.4 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 CDO69721.1 - 3.2e-05 23.8 0.6 0.00018 21.3 0.0 2.3 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 CDO69721.1 - 5.1e-05 22.3 0.0 9.8e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 CDO69721.1 - 0.00018 21.9 0.1 0.0011 19.4 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDO69721.1 - 0.00019 21.7 0.0 0.0025 18.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDO69721.1 - 0.00038 20.2 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CDO69721.1 - 0.0012 19.4 0.9 0.0039 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CDO69721.1 - 0.0031 17.5 0.0 0.015 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDO69721.1 - 0.0049 16.6 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CDO69721.1 - 0.012 16.0 0.0 0.073 13.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DNTTIP1_dimer PF18192.1 CDO69721.1 - 0.028 14.8 0.2 1 9.8 0.4 2.8 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain SKI PF01202.22 CDO69721.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase AAA_30 PF13604.6 CDO69721.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CDO69721.1 - 0.056 13.3 0.2 0.54 10.2 0.1 2.6 2 1 1 3 3 2 0 NTPase NACHT PF05729.12 CDO69721.1 - 0.062 13.2 0.1 1.9 8.4 0.0 2.8 3 0 0 3 3 3 0 NACHT domain RsgA_GTPase PF03193.16 CDO69721.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase TIP49 PF06068.13 CDO69721.1 - 0.069 12.3 0.1 0.27 10.4 0.1 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_28 PF13521.6 CDO69721.1 - 0.11 12.8 0.0 6.6 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CDO69721.1 - 0.12 12.9 0.6 0.39 11.2 0.1 2.1 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 CDO69721.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDO69721.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SPX PF03105.19 CDO69721.1 - 0.67 9.8 18.7 0.92 9.4 0.7 2.3 2 1 0 2 2 2 0 SPX domain AAA_23 PF13476.6 CDO69721.1 - 7.7 7.0 5.7 5.4 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cyt-b5 PF00173.28 CDO69724.1 - 4.4e-15 55.6 0.0 8.2e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4620 PF15399.6 CDO69724.1 - 0.072 13.5 0.3 0.072 13.5 0.3 3.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4620) ECH_1 PF00378.20 CDO69725.1 - 4.8e-13 49.0 0.0 1.9e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDO69725.1 - 6.4e-05 22.6 0.0 0.00045 19.8 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase TED PF08341.11 CDO69725.1 - 0.069 13.5 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioester domain DFRP_C PF16543.5 CDO69726.1 - 1.2e-30 105.8 3.9 1.2e-30 105.8 3.9 4.0 3 2 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 CDO69726.1 - 2e-06 27.5 9.9 2.5e-06 27.2 0.8 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDO69726.1 - 2.2e-05 24.3 5.7 2.2e-05 24.3 5.7 3.1 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 CDO69726.1 - 4.8e-05 24.0 18.3 8.9e-05 23.2 5.0 3.3 2 2 1 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 CDO69726.1 - 7.1e-05 22.5 10.5 0.00021 21.0 1.2 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CDO69726.1 - 0.0017 18.5 4.3 0.04 14.1 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDO69726.1 - 0.0025 18.2 7.5 0.38 11.3 2.8 2.6 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Oxysterol_BP PF01237.18 CDO69726.1 - 0.71 8.6 15.4 0.38 9.5 4.3 2.3 2 0 0 2 2 2 0 Oxysterol-binding protein Torus PF16131.5 CDO69727.1 - 3.8e-41 140.2 2.8 7.2e-41 139.3 2.8 1.4 1 0 0 1 1 1 1 Torus domain Nup35_RRM_2 PF14605.6 CDO69727.1 - 4.7e-05 23.3 0.0 8.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CDO69727.1 - 0.00011 21.9 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CDO69727.1 - 0.075 13.1 5.3 0.14 12.2 5.3 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 CDO69727.1 - 0.73 9.7 9.3 1.4 8.8 9.3 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 CDO69727.1 - 1.2 9.1 7.5 2.3 8.2 7.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RVT_2 PF07727.14 CDO69729.1 - 2.4e-72 243.5 0.0 3.1e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Thioredoxin PF00085.20 CDO69731.1 - 1.3e-23 82.9 0.0 1.2e-15 57.4 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CDO69731.1 - 0.17 12.4 0.0 1 9.9 0.0 2.2 2 1 0 2 2 2 0 Thioredoxin-like domain DUF455 PF04305.14 CDO69732.1 - 4.4e-92 308.1 0.0 5.7e-92 307.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 CDO69732.1 - 4.1e-06 26.6 0.0 7.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CDO69732.1 - 0.0037 17.2 0.0 0.0098 15.8 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain ATG22 PF11700.8 CDO69733.1 - 6.5e-116 387.8 7.8 7.4e-116 387.6 7.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 CDO69733.1 - 6.9e-08 31.8 40.2 9.4e-05 21.5 23.6 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.25 CDO69736.1 - 3.9e-65 219.8 0.0 3.9e-64 216.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69736.1 - 3.4e-37 128.2 0.0 1.1e-36 126.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CDO69736.1 - 3.8e-06 26.4 0.4 6.1e-06 25.7 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDO69736.1 - 1.1e-05 24.9 0.1 2.9e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDO69736.1 - 8e-05 22.7 0.3 0.013 15.5 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO69736.1 - 9.1e-05 21.6 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain WaaY PF06176.11 CDO69736.1 - 0.018 14.7 0.4 0.029 14.0 0.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.9 CDO69736.1 - 0.15 11.6 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 CDO69736.1 - 0.16 11.5 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 CDO69736.1 - 0.17 11.5 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Fungal_trans PF04082.18 CDO69738.1 - 6.6e-13 48.3 0.5 1.5e-12 47.1 0.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rad60-SLD PF11976.8 CDO69739.1 - 1.8e-10 40.5 0.0 2.6e-10 40.0 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDO69739.1 - 3.9e-08 32.9 0.0 5.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 CDO69739.1 - 0.07 13.4 0.0 0.092 13.0 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain RicinB_lectin_2 PF14200.6 CDO69740.1 - 1.5e-08 35.3 0.0 1.9e-05 25.3 0.0 2.7 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CDO69740.1 - 0.0031 17.8 0.0 3.4 7.9 0.0 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CDO69741.1 - 5.8e-21 75.0 1.3 1e-12 48.6 0.1 2.9 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CDO69741.1 - 9.7e-08 32.3 0.0 0.026 14.8 0.0 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 CDO69742.1 - 3.6e-11 43.6 0.9 5.3e-06 27.1 0.1 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Mito_carr PF00153.27 CDO69743.1 - 2.9e-20 72.0 9.2 2e-09 37.2 0.4 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Wzz PF02706.15 CDO69743.1 - 2 8.7 4.5 34 4.8 0.6 2.8 2 0 0 2 2 2 0 Chain length determinant protein TFIIS_M PF07500.14 CDO69744.1 - 3.2e-32 111.3 0.4 1e-31 109.7 0.0 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CDO69744.1 - 8.1e-17 60.8 10.9 1.4e-16 60.0 10.9 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CDO69744.1 - 4.4e-09 36.2 1.4 9.6e-09 35.1 1.4 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WD40 PF00400.32 CDO69745.1 - 1.6e-41 139.5 19.9 4.3e-08 33.7 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO69745.1 - 0.00017 21.8 1.0 0.4 11.0 0.1 4.3 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDO69745.1 - 0.01 14.5 0.8 8.3 4.9 0.0 3.6 1 1 2 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 CDO69745.1 - 0.049 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 WD40-like domain DUF3328 PF11807.8 CDO69746.1 - 3.5e-17 62.9 0.7 4.5e-17 62.6 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 CDO69748.1 - 2e-10 40.8 3.4 2.8e-10 40.3 3.3 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.9 CDO69750.1 - 4.8e-06 27.0 0.0 7.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Acetyltransf_1 PF00583.25 CDO69751.1 - 1.7e-10 41.1 0.0 3.3e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDO69751.1 - 1.8e-10 40.8 0.0 4e-10 39.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDO69751.1 - 2.7e-09 37.3 0.0 9.5e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDO69751.1 - 2.3e-05 24.4 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDO69751.1 - 0.00046 20.1 0.0 0.0009 19.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 CDO69751.1 - 0.0009 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 CDO69751.1 - 0.11 13.2 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 CDO69751.1 - 0.12 12.0 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Peptidase_M48_N PF16491.5 CDO69752.1 - 1.6e-62 210.7 8.7 1.6e-62 210.6 5.7 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CDO69752.1 - 3.6e-36 124.8 0.0 7.4e-36 123.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 CDO69752.1 - 0.05 12.8 0.1 0.095 11.9 0.1 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 ABC2_membrane PF01061.24 CDO69752.1 - 1.2 8.5 14.2 0.061 12.7 8.5 1.7 2 0 0 2 2 2 0 ABC-2 type transporter adh_short PF00106.25 CDO69753.1 - 9.2e-32 110.1 0.0 3.1e-17 62.7 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69753.1 - 1.9e-21 76.7 0.0 1.8e-11 44.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CDO69753.1 - 5e-08 33.1 0.1 8.7e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CDO69753.1 - 7.2e-07 29.3 0.0 4.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CDO69753.1 - 0.013 15.0 0.0 0.075 12.5 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF4232 PF14016.6 CDO69753.1 - 0.06 13.5 0.5 3.6 7.7 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4232) MFS_1 PF07690.16 CDO69754.1 - 1e-16 60.9 28.6 1.9e-16 60.0 24.9 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO69754.1 - 0.00014 20.9 16.5 0.0046 15.9 6.6 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter 7tm_6 PF02949.20 CDO69755.1 - 0.0029 16.7 1.6 0.0029 16.7 1.6 1.8 2 1 0 2 2 2 1 7tm Odorant receptor DUF1772 PF08592.11 CDO69755.1 - 1.1 9.5 13.9 11 6.4 7.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Dsl1_C PF11989.8 CDO69756.1 - 3.8e-11 43.1 0.2 2.2e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Zw10 PF06248.13 CDO69756.1 - 1.8e-09 36.7 0.1 0.011 14.3 0.2 3.2 3 0 0 3 3 3 3 Centromere/kinetochore Zw10 Activator-TraM PF11657.8 CDO69756.1 - 0.0027 17.5 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional activator TraM RIG-I_C PF18119.1 CDO69756.1 - 0.032 14.2 0.4 0.47 10.5 0.3 2.6 2 1 0 2 2 2 0 RIG-I receptor C-terminal domain Rep_fac_C PF08542.11 CDO69757.1 - 1.2e-19 70.4 0.0 4.1e-19 68.8 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 CDO69757.1 - 1.4e-17 64.4 0.0 2.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CDO69757.1 - 2.9e-15 56.4 0.0 3.3e-12 46.5 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CDO69757.1 - 2.1e-09 37.6 0.0 6e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 CDO69757.1 - 6.3e-07 29.3 0.0 3.2e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CDO69757.1 - 1.1e-06 28.6 0.3 0.00054 19.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 CDO69757.1 - 6.5e-06 25.5 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 CDO69757.1 - 1.2e-05 25.3 0.2 5e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CDO69757.1 - 2.4e-05 24.6 0.1 7.6e-05 23.0 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 CDO69757.1 - 5.2e-05 23.1 0.0 9.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 CDO69757.1 - 0.00016 21.5 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDO69757.1 - 0.00016 22.1 0.0 0.00072 20.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 CDO69757.1 - 0.00024 21.4 0.4 0.065 13.6 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_24 PF13479.6 CDO69757.1 - 0.00041 20.1 0.0 0.0008 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDO69757.1 - 0.00061 20.1 0.1 0.055 13.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDO69757.1 - 0.00076 19.5 0.1 0.009 16.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.29 CDO69757.1 - 0.00079 19.2 0.3 0.0024 17.7 0.3 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDO69757.1 - 0.001 19.1 0.0 0.012 15.6 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 CDO69757.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDO69757.1 - 0.0051 16.3 0.0 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 CDO69757.1 - 0.006 16.0 0.1 0.24 10.8 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein Methyltransf_31 PF13847.6 CDO69757.1 - 0.0066 16.2 0.1 0.018 14.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Viral_helicase1 PF01443.18 CDO69757.1 - 0.0089 15.8 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CDO69757.1 - 0.026 14.4 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 CDO69757.1 - 0.036 13.1 0.0 0.087 11.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein MCM PF00493.23 CDO69757.1 - 0.05 12.7 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain IstB_IS21 PF01695.17 CDO69757.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SNF2_N PF00176.23 CDO69757.1 - 0.095 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Mg_chelatase PF01078.21 CDO69757.1 - 0.098 12.0 0.0 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FliH PF02108.16 CDO69757.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Flagellar assembly protein FliH AAA_28 PF13521.6 CDO69757.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain ubiquitin PF00240.23 CDO69758.1 - 3.4e-34 116.4 0.5 3.4e-34 116.4 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 CDO69758.1 - 3.4e-26 91.1 1.9 3.4e-26 91.1 1.9 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CDO69758.1 - 3.4e-16 58.8 0.6 7.9e-16 57.7 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDO69758.1 - 2.7e-05 24.5 0.3 0.00014 22.2 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDO69758.1 - 0.00031 20.8 0.6 0.0007 19.7 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CDO69758.1 - 0.0073 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDO69758.1 - 0.0074 16.6 1.1 0.012 15.9 0.1 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 CDO69758.1 - 0.008 16.7 0.8 0.011 16.3 0.8 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CDO69758.1 - 0.019 15.0 1.1 5.9 7.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4925 PF16272.5 CDO69758.1 - 0.025 14.1 0.2 0.034 13.6 0.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4925) IBR PF01485.21 CDO69758.1 - 0.029 14.6 0.6 0.05 13.8 0.6 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF971 PF06155.12 CDO69758.1 - 0.13 12.9 0.2 0.27 11.9 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF971) LRR_4 PF12799.7 CDO69759.1 - 0.042 14.3 0.2 8.7 6.9 0.0 4.3 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) MMS19_C PF12460.8 CDO69761.1 - 3.6e-112 375.6 5.9 3.6e-112 375.6 5.9 2.1 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 CDO69761.1 - 1.3e-54 185.6 10.6 7e-49 166.7 0.1 5.0 4 2 1 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 CDO69761.1 - 2.9e-07 30.8 11.8 0.19 12.2 0.1 6.5 5 1 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 CDO69761.1 - 3.9e-07 30.4 10.0 0.00025 21.5 0.1 5.9 6 1 1 7 7 7 2 HEAT-like repeat HEAT PF02985.22 CDO69761.1 - 0.0019 18.3 6.2 16 6.1 0.1 6.2 6 0 0 6 6 6 1 HEAT repeat Ipi1_N PF12333.8 CDO69761.1 - 0.013 16.1 0.2 5.1 7.8 0.0 4.0 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation DUF4704 PF15787.5 CDO69761.1 - 0.025 13.8 0.1 0.15 11.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) Erf4 PF10256.9 CDO69761.1 - 0.15 12.2 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Methyltransf_28 PF02636.17 CDO69763.1 - 1.9e-37 129.3 0.0 3e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 CDO69763.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 CDO69763.1 - 0.024 15.3 0.0 0.097 13.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 CDO69763.1 - 0.079 13.7 0.0 0.41 11.4 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Tmemb_14 PF03647.13 CDO69764.1 - 2.9e-20 72.8 6.6 3.3e-20 72.6 6.6 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 CDO69764.1 - 0.042 14.2 1.3 0.16 12.3 1.3 2.0 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 DUF3188 PF11384.8 CDO69764.1 - 0.26 11.0 0.4 0.26 11.0 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3188) Methyltransf_25 PF13649.6 CDO69765.1 - 7.6e-13 49.0 0.0 1.2e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO69765.1 - 2.4e-11 44.1 0.0 3.8e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO69765.1 - 5.8e-09 35.9 0.0 7.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO69765.1 - 0.00012 22.8 0.0 0.00017 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CDO69765.1 - 0.0021 17.7 0.1 0.005 16.5 0.1 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CDO69765.1 - 0.035 14.1 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CDO69765.1 - 0.052 13.1 0.0 0.07 12.7 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 CDO69765.1 - 0.09 12.1 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Voltage_CLC PF00654.20 CDO69766.1 - 1.1e-85 288.1 26.7 1.1e-85 288.1 26.7 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CDO69766.1 - 4.1e-06 27.1 0.3 0.081 13.4 0.0 3.0 3 0 0 3 3 3 2 CBS domain DSPc PF00782.20 CDO69767.1 - 7.9e-32 109.9 0.0 1.1e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDO69767.1 - 0.0014 18.2 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 CDO69767.1 - 0.0035 16.9 0.1 0.0054 16.3 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 CDO69767.1 - 0.0037 16.9 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CDO69767.1 - 0.068 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 CDO69767.1 - 0.11 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Peptidase_S10 PF00450.22 CDO69768.1 - 4.3e-54 184.5 0.0 9.4e-46 157.0 0.0 2.4 2 1 0 2 2 2 2 Serine carboxypeptidase Mucin PF01456.17 CDO69768.1 - 0.42 10.6 11.2 0.8 9.7 11.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein RVT_1 PF00078.27 CDO69769.1 - 0.069 12.7 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ZZ PF00569.17 CDO69770.1 - 4.8e-18 64.7 62.7 2e-06 27.5 8.1 6.2 6 0 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.24 CDO69770.1 - 0.00056 19.8 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 PB1 domain TTSSLRR PF12468.8 CDO69770.1 - 0.057 13.7 0.3 0.26 11.5 0.0 2.3 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein C1_2 PF03107.16 CDO69770.1 - 0.35 11.2 60.2 0.04 14.2 8.3 6.6 7 0 0 7 7 7 0 C1 domain Yippee-Mis18 PF03226.14 CDO69770.1 - 0.46 10.7 0.0 0.46 10.7 0.0 4.6 4 1 0 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Med4 PF10018.9 CDO69771.1 - 5.1e-23 81.8 0.0 7.6e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Cas_GSU0053 PF09617.10 CDO69771.1 - 0.14 12.1 0.1 0.21 11.6 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Muted PF14942.6 CDO69771.1 - 0.15 12.4 0.4 0.25 11.7 0.4 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Trimer_CC PF08954.11 CDO69771.1 - 0.2 11.3 7.7 1 8.9 0.3 2.5 2 0 0 2 2 2 0 Trimerisation motif Peptidase_S10 PF00450.22 CDO69772.1 - 1.3e-45 156.6 0.3 2.2e-29 103.1 0.5 2.9 3 0 0 3 3 3 2 Serine carboxypeptidase Carn_acyltransf PF00755.20 CDO69773.1 - 1.5e-182 608.3 0.0 1.8e-182 608.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF5519 PF17648.1 CDO69773.1 - 0.017 15.0 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5519) Polysacc_deac_1 PF01522.21 CDO69774.1 - 2.2e-26 92.2 0.0 4.6e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Sec1 PF00995.23 CDO69775.1 - 6.7e-123 411.9 0.0 7.8e-123 411.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CNH PF00780.22 CDO69776.1 - 2.1e-77 260.5 0.0 3.7e-77 259.6 0.0 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 CDO69776.1 - 1.2e-41 141.9 0.1 2.3e-41 141.1 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 CDO69776.1 - 3.5e-37 128.4 0.0 5.6e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 CDO69776.1 - 4e-15 55.6 0.1 8.5e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 CDO69776.1 - 0.00049 19.9 2.2 0.0025 17.6 1.0 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CDO69776.1 - 0.0048 17.4 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 PH domain EI24 PF07264.11 CDO69778.1 - 6.8e-13 49.2 10.4 1.9e-12 47.8 10.4 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DnaJ-X PF14308.6 CDO69779.1 - 2.8e-67 226.2 0.1 2.8e-67 226.2 0.1 2.4 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 CDO69779.1 - 4.8e-14 52.2 0.1 3.4e-08 33.5 0.0 2.9 2 0 0 2 2 2 2 DnaJ domain MSA-2c PF12238.8 CDO69779.1 - 0.08 12.9 2.7 0.19 11.7 2.7 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c PspB PF06667.12 CDO69779.1 - 0.47 10.5 5.5 0.27 11.3 1.8 2.3 2 0 0 2 2 2 0 Phage shock protein B dbPDZ_assoc PF16610.5 CDO69780.1 - 4 7.7 13.8 0.34 11.2 6.7 2.1 1 1 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 WLM PF08325.10 CDO69781.1 - 2.5e-44 151.7 0.9 3e-44 151.4 0.2 1.5 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.23 CDO69781.1 - 2.3e-08 33.6 0.0 4.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 CDO69781.1 - 0.0027 17.6 0.0 0.016 15.1 0.0 2.2 3 0 0 3 3 3 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 CDO69781.1 - 0.0087 15.9 0.0 0.027 14.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SVIP PF15811.5 CDO69781.1 - 0.03 14.8 0.2 0.03 14.8 0.2 1.9 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Ubiquitin_2 PF14560.6 CDO69781.1 - 0.045 14.2 0.0 0.094 13.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain BTB PF00651.31 CDO69783.1 - 8.6e-15 54.9 0.0 7.2e-06 26.2 0.0 3.2 3 1 0 3 3 3 2 BTB/POZ domain RCC1 PF00415.18 CDO69783.1 - 1.3e-11 44.9 0.0 0.019 15.6 0.0 4.7 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 CDO69783.1 - 2.2e-10 40.9 4.2 8.7e-07 29.4 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDO69783.1 - 1.2e-09 38.7 0.1 4.3e-09 36.8 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDO69783.1 - 3.4e-09 36.8 1.4 7.5e-05 22.9 0.2 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDO69783.1 - 7.7e-08 32.0 0.4 0.015 15.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CDO69783.1 - 0.0057 17.1 6.4 0.28 11.7 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Plavaka PF18759.1 CDO69785.1 - 9.7e-14 51.3 0.0 1.8e-08 34.0 0.0 3.5 4 0 0 4 4 4 2 Plavaka transposase E1-E2_ATPase PF00122.20 CDO69787.1 - 1.8e-42 144.9 1.6 5.7e-42 143.3 1.6 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CDO69787.1 - 8.4e-29 101.4 0.3 1.7e-28 100.4 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CDO69787.1 - 3.4e-05 24.2 0.1 8.1e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain HAD PF12710.7 CDO69787.1 - 0.0018 18.7 0.1 0.004 17.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4006 PF13179.6 CDO69787.1 - 0.14 12.1 0.2 0.39 10.7 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF4006) p450 PF00067.22 CDO69788.1 - 5.7e-61 206.7 0.0 2.4e-60 204.6 0.0 2.0 2 1 0 2 2 2 1 Cytochrome P450 UvrD-helicase PF00580.21 CDO69790.1 - 0.22 11.0 0.0 0.26 10.7 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain VPS9 PF02204.18 CDO69791.1 - 6.3e-18 64.9 0.0 2.8e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain BUD22 PF09073.10 CDO69791.1 - 0.098 12.0 16.0 0.14 11.5 0.6 2.2 2 0 0 2 2 2 0 BUD22 BSP_II PF05432.11 CDO69791.1 - 0.63 9.7 18.0 0.12 12.0 4.5 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.10 CDO69791.1 - 2.5 8.6 14.2 0.24 11.8 6.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 CDO69791.1 - 4.1 7.1 20.7 2.9 7.5 7.7 2.3 2 0 0 2 2 2 0 FAM176 family ZinT PF09223.11 CDO69792.1 - 0.089 12.7 0.5 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment Pro_isomerase PF00160.21 CDO69793.1 - 1e-28 100.6 0.6 2.2e-28 99.5 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thymidylate_kin PF02223.17 CDO69794.1 - 6.6e-47 159.6 0.0 7.7e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 CDO69794.1 - 0.035 14.7 0.1 0.11 13.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain dNK PF01712.19 CDO69794.1 - 0.15 11.9 0.0 0.77 9.6 0.0 2.2 1 1 0 1 1 1 0 Deoxynucleoside kinase Zds_C PF08632.10 CDO69796.1 - 1.3e-28 98.5 1.0 2.6e-28 97.5 1.0 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2076 PF09849.9 CDO69796.1 - 0.00044 20.4 1.4 0.00044 20.4 1.4 3.3 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) Plavaka PF18759.1 CDO69799.1 - 6.2e-118 393.7 0.0 8.2e-118 393.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 CDO69802.1 - 5.9e-52 176.9 0.1 7.4e-52 176.6 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase TonB_C PF03544.14 CDO69803.1 - 0.15 12.6 0.0 0.55 10.7 0.0 2.0 2 0 0 2 2 2 0 Gram-negative bacterial TonB protein C-terminal DUF3094 PF11293.8 CDO69804.1 - 0.11 12.3 0.0 4.6 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) ABC_tran_CTD PF16326.5 CDO69805.1 - 0.0068 16.6 1.3 0.031 14.5 1.0 2.4 1 1 0 1 1 1 1 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 CDO69805.1 - 0.024 14.7 3.0 0.037 14.1 1.3 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation EF-hand_1 PF00036.32 CDO69805.1 - 0.03 13.9 0.0 0.14 11.8 0.0 2.2 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 CDO69805.1 - 0.14 12.2 0.4 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain HalX PF08663.10 CDO69805.1 - 0.14 12.5 3.0 0.66 10.3 0.2 2.8 1 1 1 2 2 2 0 HalX domain Plasmid_RAQPRD PF09686.10 CDO69806.1 - 0.17 12.1 0.3 13 6.0 0.0 2.8 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) LSM PF01423.22 CDO69807.1 - 6.2e-12 45.0 0.1 7.1e-12 44.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain ArAE_2 PF10334.9 CDO69808.1 - 2.2e-57 194.5 0.1 5.2e-57 193.3 0.1 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 CDO69808.1 - 5.1e-34 118.1 18.2 1e-31 110.6 14.2 3.9 2 1 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CDO69808.1 - 1.8e-07 31.3 17.3 1.8e-07 31.3 17.3 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like WD40 PF00400.32 CDO69809.1 - 7.3e-34 115.3 16.3 3.4e-05 24.5 0.0 10.9 11 0 0 11 11 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO69809.1 - 5.5e-13 49.0 0.0 0.017 15.4 0.0 6.6 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 CDO69809.1 - 1.5e-06 28.3 0.5 4.9e-06 26.6 0.5 1.9 1 1 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 CDO69809.1 - 6.8e-06 25.3 0.3 0.32 9.9 0.0 5.2 4 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDO69809.1 - 0.00018 21.4 0.0 0.094 12.6 0.0 3.9 3 1 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CDO69809.1 - 0.00041 19.0 0.1 0.29 9.6 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 CDO69809.1 - 0.0012 18.3 0.0 0.4 10.0 0.0 3.3 2 1 2 4 4 4 1 WD40-like domain AAA_16 PF13191.6 CDO69809.1 - 0.0015 19.0 0.1 0.006 17.0 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 CDO69809.1 - 0.0047 16.2 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 CDO69809.1 - 0.0091 16.3 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain PD40 PF07676.12 CDO69809.1 - 0.27 11.2 5.7 14 5.8 0.1 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat HAD_2 PF13419.6 CDO69811.1 - 1.2e-08 35.2 0.0 1.5e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDO69811.1 - 3.2e-08 34.1 0.0 4.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDO69811.1 - 8.6e-08 32.1 0.1 1.4e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HSP70 PF00012.20 CDO69812.1 - 3.5e-58 197.2 1.0 5e-43 147.2 0.2 3.5 2 2 1 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.13 CDO69812.1 - 2.4e-09 36.5 0.0 7.8e-09 34.8 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein Radial_spoke PF04712.12 CDO69812.1 - 0.85 8.5 10.2 1.6 7.6 10.2 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Myc_N PF01056.18 CDO69812.1 - 2.5 7.9 6.9 4.7 7.0 6.9 1.4 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.6 CDO69812.1 - 4.8 6.8 7.5 11 5.7 7.5 1.5 1 0 0 1 1 1 0 FAM176 family DUF4637 PF15470.6 CDO69812.1 - 5.7 6.6 9.3 11 5.7 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Hamartin PF04388.12 CDO69812.1 - 7.9 5.0 7.3 0.55 8.8 0.4 2.0 2 0 0 2 2 2 0 Hamartin protein UCH PF00443.29 CDO69813.1 - 5.2e-44 150.7 0.0 8.4e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CDO69813.1 - 1.6e-25 88.6 2.5 3.4e-12 46.0 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 CDO69813.1 - 3.2e-24 84.4 0.3 5.9e-24 83.6 0.3 1.5 1 0 0 1 1 1 1 Variant UBP zinc finger UCH_1 PF13423.6 CDO69813.1 - 7.4e-17 61.9 0.0 3.3e-15 56.5 0.0 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDO69813.1 - 4.6e-06 26.9 1.9 1.9e-05 24.9 1.9 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-C2HE PF16278.5 CDO69813.1 - 0.0045 17.4 0.5 2.4 8.7 0.1 2.9 2 0 0 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger UBA_4 PF14555.6 CDO69813.1 - 0.068 13.0 0.6 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 UBA-like domain NAP PF00956.18 CDO69814.1 - 2.5e-87 292.5 2.9 2.5e-87 292.5 2.9 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Tom5 PF10642.9 CDO69814.1 - 0.12 12.4 4.1 5 7.2 1.0 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Cwf_Cwc_15 PF04889.12 CDO69814.1 - 0.44 10.3 13.3 0.98 9.1 13.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Treacle PF03546.14 CDO69814.1 - 0.48 9.2 10.1 1.3 7.8 5.3 2.1 2 0 0 2 2 2 0 Treacher Collins syndrome protein Treacle BUD22 PF09073.10 CDO69814.1 - 1.9 7.7 13.1 3.4 6.9 13.1 1.4 1 0 0 1 1 1 0 BUD22 zf-4CXXC_R1 PF10497.9 CDO69815.1 - 2.2e-13 50.3 11.3 4.4e-13 49.3 11.3 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Pkinase PF00069.25 CDO69817.1 - 1.9e-23 83.2 0.0 4e-22 78.8 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69817.1 - 3.1e-10 39.8 0.2 1.8e-05 24.2 0.0 3.6 2 1 0 2 2 2 2 Protein tyrosine kinase GMC_oxred_N PF00732.19 CDO69819.1 - 8.6e-55 186.2 0.0 1.2e-54 185.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO69819.1 - 8e-32 110.7 0.0 1.4e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 CDO69819.1 - 0.0007 18.9 0.1 0.021 14.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO69819.1 - 0.0027 17.9 0.0 0.0067 16.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDO69819.1 - 0.0031 17.2 0.3 0.0072 16.0 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CDO69819.1 - 0.0047 16.0 0.1 0.0089 15.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CDO69819.1 - 0.0049 16.0 0.1 0.18 10.8 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CDO69819.1 - 0.046 13.0 0.1 0.077 12.2 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 CDO69819.1 - 0.053 13.5 0.3 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CDO69820.1 - 9.4e-19 67.8 0.0 2.3e-16 60.0 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 CDO69820.1 - 1.6e-17 63.1 0.0 3.1e-16 58.9 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CDO69820.1 - 1.6e-13 50.5 0.1 1.9e-10 40.4 0.1 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDO69820.1 - 4.9e-12 45.6 0.0 1.6e-08 34.1 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 CDO69820.1 - 1.5e-06 28.7 0.2 0.0057 17.2 0.1 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO69820.1 - 0.00018 21.7 0.0 0.0033 17.6 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CDO69820.1 - 0.00047 19.5 0.0 0.0042 16.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CDO69820.1 - 0.00058 19.6 0.5 0.16 11.5 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 CDO69820.1 - 0.0028 16.4 0.0 0.066 11.9 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 CDO69820.1 - 0.0055 16.1 0.0 0.052 12.9 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 CDO69820.1 - 0.019 14.0 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 CDO69820.1 - 0.056 12.7 0.0 9.7 5.3 0.0 3.1 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase GIDA PF01134.22 CDO69820.1 - 0.057 12.5 0.1 0.24 10.4 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A SnoaL_2 PF12680.7 CDO69820.1 - 0.065 13.9 0.1 0.54 10.9 0.0 2.3 2 0 0 2 2 2 0 SnoaL-like domain Gti1_Pac2 PF09729.9 CDO69822.1 - 2.1e-43 148.5 1.9 1.4e-33 116.5 0.2 2.3 1 1 0 2 2 2 2 Gti1/Pac2 family Oxysterol_BP PF01237.18 CDO69823.1 - 2.5e-136 454.4 0.0 4e-136 453.7 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.7 CDO69823.1 - 7e-16 58.6 0.0 9e-08 32.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDO69823.1 - 5.5e-14 52.0 0.5 8.4e-09 35.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 CDO69823.1 - 6.1e-12 46.0 0.0 1.7e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 CDO69823.1 - 2.7e-11 42.6 0.4 0.094 13.3 0.2 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 CDO69823.1 - 9.1e-11 42.1 0.4 0.00011 22.7 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDO69823.1 - 1.1e-10 41.4 1.3 0.018 15.5 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat PH_8 PF15409.6 CDO69823.1 - 8.2e-06 26.0 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CDO69823.1 - 6.9e-05 23.2 0.1 0.00024 21.5 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Pyr_redox_2 PF07992.14 CDO69824.1 - 6.5e-41 140.5 0.1 1e-39 136.5 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 CDO69824.1 - 7.9e-19 67.5 0.0 2.4e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.27 CDO69824.1 - 2e-15 57.1 0.8 3e-13 50.1 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 CDO69824.1 - 3.3e-14 53.0 4.3 1.6e-12 47.6 4.2 2.7 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 CDO69824.1 - 6.4e-13 48.4 0.0 1.5e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 CDO69824.1 - 2.8e-11 43.2 1.0 1e-10 41.4 0.0 2.4 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain NIR_SIR PF01077.22 CDO69824.1 - 4.6e-11 42.5 0.0 1.5e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rubredoxin_C PF18267.1 CDO69824.1 - 0.0077 16.1 0.1 2.7 8.0 0.0 2.9 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 CDO69824.1 - 0.025 14.6 3.6 7.4 6.5 0.1 3.7 2 2 2 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CDO69824.1 - 0.036 13.2 2.9 2.3 7.2 0.0 2.9 2 1 1 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.21 CDO69824.1 - 2.9 7.1 6.0 0.16 11.3 0.3 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ECH_1 PF00378.20 CDO69825.1 - 7.3e-38 130.3 0.0 9.6e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDO69825.1 - 1.1e-22 81.0 0.2 5.3e-17 62.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_C54 PF03416.19 CDO69826.1 - 2.5e-101 338.7 0.0 3.4e-101 338.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Ras PF00071.22 CDO69827.1 - 1e-38 132.5 0.0 1.4e-36 125.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CDO69827.1 - 2.5e-28 98.7 0.0 3.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO69827.1 - 2.5e-08 33.6 0.0 7.6e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDO69827.1 - 2e-05 24.6 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDO69827.1 - 0.00044 19.7 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDO69827.1 - 0.0017 17.9 0.0 0.006 16.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDO69827.1 - 0.0068 16.3 0.1 0.038 13.9 0.2 2.0 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 CDO69827.1 - 0.044 13.1 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 AIG1 family DEAD PF00270.29 CDO69828.1 - 3.2e-21 75.9 0.0 5.8e-19 68.5 0.0 2.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO69828.1 - 5.9e-10 39.5 0.0 3.5e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO69828.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit adh_short PF00106.25 CDO69829.1 - 4.5e-47 160.0 0.6 5.6e-47 159.7 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69829.1 - 4.5e-34 118.0 0.2 5.8e-34 117.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO69829.1 - 5.6e-09 36.2 0.0 9.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CDO69829.1 - 1.4e-06 27.9 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 CDO69829.1 - 0.002 18.0 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CDO69829.1 - 0.0045 16.1 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.15 CDO69829.1 - 0.046 13.6 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DPBB_1 PF03330.18 CDO69829.1 - 0.063 13.6 0.1 0.39 11.0 0.0 2.2 2 1 1 3 3 3 0 Lytic transglycolase F-box-like PF12937.7 CDO69830.1 - 2.3e-11 43.4 2.3 4.5e-11 42.5 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDO69830.1 - 3.5 7.6 5.9 3 7.8 0.3 3.4 3 1 0 3 3 3 0 F-box domain Aldedh PF00171.22 CDO69831.1 - 8.7e-187 621.2 0.0 9.8e-187 621.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Acetyltransf_3 PF13302.7 CDO69832.1 - 1.5e-14 54.8 0.0 1.9e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO69832.1 - 0.00011 22.4 0.0 0.001 19.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CDO69832.1 - 0.0013 18.7 0.0 0.0075 16.2 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 CDO69832.1 - 0.0029 17.3 0.0 0.0072 16.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDO69832.1 - 0.0064 16.9 0.0 0.0087 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 CDO69832.1 - 0.041 13.5 0.0 0.36 10.4 0.0 2.0 1 1 0 1 1 1 0 GNAT acetyltransferase Gpr1_Fun34_YaaH PF01184.19 CDO69833.1 - 5.1e-75 251.6 18.4 6.3e-75 251.3 18.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ABC_tran PF00005.27 CDO69834.1 - 4.8e-24 85.4 0.0 1.1e-23 84.3 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDO69834.1 - 4.7e-09 36.5 0.0 0.00074 19.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDO69834.1 - 4.4e-07 29.6 0.0 0.01 15.3 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDO69834.1 - 2.6e-05 24.1 0.0 0.0015 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 CDO69834.1 - 0.0021 18.5 0.0 0.004 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 CDO69834.1 - 0.0021 17.4 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 CDO69834.1 - 0.0024 17.6 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CDO69834.1 - 0.0055 17.2 0.0 0.0096 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDO69834.1 - 0.0073 16.6 0.0 0.032 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDO69834.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CDO69834.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dimer_Tnp_hAT PF05699.14 CDO69834.1 - 0.047 13.5 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region AAA_27 PF13514.6 CDO69834.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 CDO69834.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Y_phosphatase PF00102.27 CDO69835.1 - 5e-54 183.3 2.7 4.4e-46 157.4 0.2 3.8 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 CDO69835.1 - 8.4e-08 32.7 0.0 2.6e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 CDO69835.1 - 0.0026 17.8 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CDO69835.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain F-box-like PF12937.7 CDO69836.1 - 2.1e-05 24.3 1.3 9e-05 22.3 0.1 2.7 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 CDO69836.1 - 0.0027 18.1 3.0 1.4 9.4 0.1 4.7 3 1 3 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDO69836.1 - 0.068 12.9 0.6 0.49 10.2 0.1 2.8 3 0 0 3 3 3 0 Leucine rich repeat V-ATPase_C PF03223.15 CDO69836.1 - 0.095 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit C ABC_tran PF00005.27 CDO69837.1 - 2e-24 86.7 0.0 6.2e-24 85.1 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDO69837.1 - 1.9e-09 37.8 0.0 0.00017 21.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDO69837.1 - 5.5e-06 26.0 0.0 0.086 12.3 0.2 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDO69837.1 - 3e-05 23.9 0.0 0.00072 19.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 CDO69837.1 - 0.00089 19.8 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CDO69837.1 - 0.001 18.7 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CDO69837.1 - 0.0055 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDO69837.1 - 0.0083 16.4 0.0 0.029 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 CDO69837.1 - 0.0091 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CDO69837.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 CDO69837.1 - 0.017 15.5 0.0 0.051 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 CDO69837.1 - 0.078 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.6 CDO69837.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CDO69837.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 CDO69837.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDO69837.1 - 0.21 11.2 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UMP1 PF05348.11 CDO69838.1 - 2.5e-36 124.5 2.3 2.9e-36 124.3 2.3 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 MHC2-interact PF09307.10 CDO69838.1 - 0.3 11.1 3.0 1.5 8.8 0.3 2.1 1 1 1 2 2 2 0 CLIP, MHC2 interacting PARP_reg PF02877.14 CDO69839.1 - 1.3e-54 183.9 0.0 1.4e-38 132.1 0.0 2.4 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CDO69839.1 - 2e-39 133.5 10.5 5.8e-21 74.3 0.3 2.9 3 0 0 3 3 3 2 WGR domain PARP PF00644.20 CDO69839.1 - 7.5e-29 100.7 10.5 5.5e-13 49.0 0.0 4.5 4 2 2 6 6 6 3 Poly(ADP-ribose) polymerase catalytic domain DAAD PF18752.1 CDO69839.1 - 0.24 11.2 2.0 0.29 10.9 0.4 1.9 2 0 0 2 2 2 0 Dictyosteliid AID/APOBEC-like Deaminase DUF659 PF04937.15 CDO69842.1 - 1.6e-13 50.8 0.1 2.6e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) GPI-anchored PF10342.9 CDO69843.1 - 4.7e-07 30.5 0.1 9e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MFS_1 PF07690.16 CDO69845.1 - 5.3e-25 88.1 52.6 3e-16 59.3 13.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO69845.1 - 1.6e-21 76.8 18.3 2.9e-18 66.0 3.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter CMAS PF02353.20 CDO69847.1 - 1.2e-44 152.7 0.0 9.1e-29 100.6 0.0 4.7 5 0 0 5 5 5 4 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CDO69847.1 - 3.6e-07 30.8 0.0 7.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDO69847.1 - 0.00044 19.8 0.0 0.00078 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CDO69847.1 - 0.0036 17.1 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO69847.1 - 0.0079 16.9 0.0 0.019 15.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 CDO69847.1 - 0.0094 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.20 CDO69847.1 - 0.057 12.5 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 CDO69847.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 CDO69847.1 - 0.094 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PCMT PF01135.19 CDO69847.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rif1_N PF12231.8 CDO69848.1 - 0.0051 15.9 0.5 0.0087 15.1 0.5 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Dcc1 PF09724.9 CDO69848.1 - 0.092 12.0 0.2 0.94 8.7 0.1 2.3 2 0 0 2 2 2 0 Sister chromatid cohesion protein Dcc1 ICMT PF04140.14 CDO69849.1 - 1.9e-17 63.5 0.2 2e-15 56.9 0.1 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO69849.1 - 1.1e-10 41.8 0.3 4.8e-10 39.8 0.1 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO69849.1 - 3.7e-09 35.8 0.0 5.2e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 CDO69850.1 - 4.8e-15 55.8 0.0 1e-14 54.7 0.0 1.5 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO69850.1 - 2.4e-12 47.2 0.0 3.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO69850.1 - 1.1e-07 31.0 0.0 1.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.11 CDO69850.1 - 0.0011 18.5 0.3 0.0014 18.2 0.3 1.2 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.12 CDO69850.1 - 0.018 14.6 0.2 0.022 14.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ALIX_LYPXL_bnd PF13949.6 CDO69850.1 - 0.36 10.1 1.1 0.5 9.6 1.1 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV CENP-X PF09415.10 CDO69851.1 - 0.037 14.4 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 CENP-S associating Centromere protein X ICMT PF04140.14 CDO69852.1 - 1.2e-13 51.3 2.3 2.4e-13 50.3 0.0 2.5 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO69852.1 - 1.4e-12 47.9 0.5 7.7e-12 45.5 0.5 2.1 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO69852.1 - 3.4e-05 22.8 0.0 5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CDO69852.1 - 0.025 14.1 0.4 0.036 13.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ICMT PF04140.14 CDO69853.1 - 1.4e-13 51.1 0.1 5e-12 46.1 0.1 2.5 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO69853.1 - 5.7e-12 46.0 0.2 5.5e-10 39.6 0.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO69853.1 - 7.2e-05 21.7 0.0 0.00012 20.9 0.0 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1656 PF07869.12 CDO69853.1 - 0.42 10.7 0.2 0.42 10.7 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1656) DUF3188 PF11384.8 CDO69853.1 - 1.1 9.1 6.1 2.4 7.9 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) PRP1_N PF06424.12 CDO69855.1 - 1.3e-50 171.7 3.7 1.3e-50 171.7 3.7 2.5 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CDO69855.1 - 6.4e-28 95.1 37.2 0.00025 21.6 0.2 14.7 5 4 10 15 15 15 10 Tetratricopeptide repeat TPR_19 PF14559.6 CDO69855.1 - 1.7e-15 57.2 17.9 0.0064 17.0 1.2 8.0 4 3 5 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 CDO69855.1 - 7.7e-14 52.1 18.3 2.7e-06 27.9 0.1 6.7 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 CDO69855.1 - 4.2e-08 33.3 6.6 0.15 12.7 0.0 8.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDO69855.1 - 1e-07 31.8 3.6 1.9 9.0 0.1 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDO69855.1 - 1.4e-06 28.3 8.5 0.09 12.9 0.1 6.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO69855.1 - 3.5e-06 26.6 1.8 0.008 15.8 0.1 4.9 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.17 CDO69855.1 - 8.1e-06 25.6 18.7 0.019 15.1 0.3 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat NARP1 PF12569.8 CDO69855.1 - 0.0022 17.0 10.6 0.0032 16.5 0.1 4.4 4 1 0 5 5 5 1 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 CDO69855.1 - 0.0023 17.7 19.1 0.0041 16.8 3.1 5.2 4 2 2 6 6 6 2 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 CDO69855.1 - 0.0028 17.8 12.1 0.029 14.6 0.2 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat Suf PF05843.14 CDO69855.1 - 0.003 17.6 0.5 8.7 6.2 0.0 4.4 4 2 1 5 5 5 1 Suppressor of forked protein (Suf) DUF3808 PF10300.9 CDO69855.1 - 0.005 15.6 0.8 2.3 6.8 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3808) TPR_1 PF00515.28 CDO69855.1 - 0.013 15.3 3.6 1.8 8.5 0.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat LemA PF04011.12 CDO69855.1 - 0.02 14.7 2.5 0.32 10.8 0.1 3.1 4 0 0 4 4 4 0 LemA family TPR_12 PF13424.6 CDO69855.1 - 4.8 7.6 16.1 2.6 8.4 1.0 6.4 6 1 3 9 9 8 0 Tetratricopeptide repeat Asp PF00026.23 CDO69856.1 - 5.4e-43 147.6 0.0 8.7e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO69856.1 - 1.3e-06 28.8 11.1 9.2e-06 26.0 5.5 3.5 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO69856.1 - 0.13 12.9 4.1 3 8.5 1.9 3.1 2 1 0 2 2 2 0 Aspartyl protease DUF515 PF04415.12 CDO69856.1 - 6.7 5.0 10.2 11 4.3 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Mito_carr PF00153.27 CDO69857.1 - 1.5e-33 114.5 4.1 2.2e-12 46.8 0.1 3.9 4 1 0 4 4 4 3 Mitochondrial carrier protein zf-rbx1 PF12678.7 CDO69859.1 - 1.6e-07 31.5 2.4 4.4e-07 30.1 2.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDO69859.1 - 3.1e-06 27.4 2.5 3.1e-06 27.4 2.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDO69859.1 - 0.00081 19.2 2.3 0.00081 19.2 2.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO69859.1 - 0.0084 16.0 1.6 0.015 15.1 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDO69859.1 - 0.015 15.1 1.0 0.094 12.6 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CDO69859.1 - 0.016 14.8 0.5 0.035 13.7 0.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CDO69859.1 - 0.028 14.5 0.1 0.064 13.3 0.1 1.7 1 1 0 1 1 1 0 RING-type zinc-finger CsbD PF05532.12 CDO69859.1 - 0.038 13.9 0.3 0.088 12.7 0.3 1.5 1 0 0 1 1 1 0 CsbD-like zf-ANAPC11 PF12861.7 CDO69859.1 - 0.074 13.1 0.3 0.074 13.1 0.3 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 CDO69859.1 - 0.08 13.0 1.7 0.21 11.6 1.7 1.7 1 0 0 1 1 1 0 Zinc-finger TBCA PF02970.16 CDO69859.1 - 0.088 13.1 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Tubulin binding cofactor A zf-RING_5 PF14634.6 CDO69859.1 - 0.093 12.7 3.0 0.22 11.5 3.0 1.6 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 CDO69859.1 - 0.13 12.2 4.1 0.18 11.7 1.9 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FliJ PF02050.16 CDO69859.1 - 0.14 12.3 0.3 3.8 7.8 0.0 3.0 3 0 0 3 3 3 0 Flagellar FliJ protein RINGv PF12906.7 CDO69859.1 - 0.41 10.8 3.6 0.11 12.6 0.3 1.8 2 0 0 2 2 1 0 RING-variant domain Hist_deacetyl PF00850.19 CDO69860.1 - 6.8e-54 183.4 0.4 8.6e-54 183.1 0.4 1.2 1 0 0 1 1 1 1 Histone deacetylase domain NUDE_C PF04880.13 CDO69861.1 - 3.6 8.0 5.2 5.7 7.4 5.2 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DAO PF01266.24 CDO69862.1 - 1.8e-53 182.4 0.1 2.5e-53 181.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CDO69862.1 - 5.4e-46 155.6 0.0 9e-46 154.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CDO69862.1 - 4.3e-07 29.4 5.7 4e-06 26.2 5.7 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CDO69862.1 - 5.5e-06 26.0 2.0 8.2e-05 22.1 1.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDO69862.1 - 0.00032 20.0 0.3 0.0013 18.1 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDO69862.1 - 0.0013 18.1 0.8 0.011 15.0 0.8 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CDO69862.1 - 0.0021 18.2 0.5 0.01 16.1 0.5 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CDO69862.1 - 0.0032 16.6 0.5 0.076 12.1 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CDO69862.1 - 0.012 14.7 0.2 1.1 8.3 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 CDO69862.1 - 0.029 13.1 0.3 0.045 12.5 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 CDO69862.1 - 0.029 14.9 0.2 0.076 13.6 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CDO69862.1 - 0.041 13.8 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 CDO69862.1 - 0.073 12.3 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO69862.1 - 0.097 11.9 0.2 0.18 11.0 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Histone PF00125.24 CDO69863.1 - 4.4e-50 169.4 3.1 4.9e-50 169.3 3.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CDO69863.1 - 2.6e-05 24.5 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CDO69863.1 - 9.9e-05 22.4 0.1 9.9e-05 22.4 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CDO69863.1 - 0.0012 19.1 1.3 0.0014 18.9 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 CDO69863.1 - 0.002 18.7 2.1 0.0026 18.4 2.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 CDO69863.1 - 0.088 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 CDO69863.1 - 0.1 12.7 0.2 0.19 11.8 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit SPRY PF00622.28 CDO69865.1 - 6.1e-09 36.0 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 SPRY domain GDA1_CD39 PF01150.17 CDO69866.1 - 4.6e-92 308.9 0.0 6e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family bZIP_1 PF00170.21 CDO69866.1 - 0.0051 16.9 6.8 0.011 15.9 6.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDO69866.1 - 0.1 12.7 7.7 0.22 11.6 7.7 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Ppx-GppA PF02541.16 CDO69866.1 - 0.19 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RhoGAP PF00620.27 CDO69867.1 - 1.1e-30 106.5 0.0 1.8e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 CDO69867.1 - 2e-28 99.2 0.7 2.3e-27 95.8 0.3 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CDO69867.1 - 8.6e-05 22.3 0.1 0.00016 21.4 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Methyltransf_31 PF13847.6 CDO69868.1 - 4.7e-25 88.1 0.0 6.1e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO69868.1 - 3.8e-24 85.2 0.0 9.4e-24 83.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO69868.1 - 5.8e-24 84.6 0.0 1.1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDO69868.1 - 1.1e-16 60.9 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CDO69868.1 - 5.2e-16 59.2 0.0 7.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO69868.1 - 1.7e-10 41.0 0.0 2.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CDO69868.1 - 3.4e-08 33.3 0.0 4.7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 CDO69868.1 - 8.9e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.16 CDO69868.1 - 1.8e-06 26.9 0.0 2.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 CDO69868.1 - 3.7e-05 23.3 0.0 5.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CDO69868.1 - 0.00029 20.7 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 CDO69868.1 - 0.0014 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_2 PF00891.18 CDO69868.1 - 0.0018 17.6 0.1 0.0024 17.2 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 CDO69868.1 - 0.0055 15.8 0.0 0.0071 15.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Catalase_C PF18011.1 CDO69868.1 - 0.018 14.6 0.0 0.057 13.1 0.0 1.8 2 0 0 2 2 2 0 C-terminal domain found in long catalases CMAS PF02353.20 CDO69868.1 - 0.026 13.8 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltr_RsmB-F PF01189.17 CDO69868.1 - 0.033 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F NodS PF05401.11 CDO69868.1 - 0.041 13.5 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Na_H_Exchanger PF00999.21 CDO69869.1 - 1.1e-44 152.9 31.4 1.1e-44 152.9 31.4 2.1 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Nop PF01798.18 CDO69870.1 - 1.3e-85 286.6 0.0 1.3e-85 286.6 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDO69870.1 - 2.8e-19 69.3 0.2 2.8e-19 69.3 0.2 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain SRP-alpha_N PF04086.13 CDO69870.1 - 0.2 11.6 27.7 0.26 11.2 27.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Clp_N PF02861.20 CDO69870.1 - 5.9 7.1 6.3 24 5.1 0.2 3.6 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component Cytochrome-c551 PF10643.9 CDO69871.1 - 0.23 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 zf-RING_2 PF13639.6 CDO69872.1 - 1.6e-10 41.1 11.3 2.3e-07 31.1 1.9 3.4 3 0 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.7 CDO69872.1 - 1.3e-07 31.8 9.6 9.6e-07 29.0 0.3 3.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CDO69872.1 - 3.6e-06 26.6 7.7 0.0004 20.1 0.5 3.3 3 0 0 3 3 3 2 RING-like zinc finger zf-RING_UBOX PF13445.6 CDO69872.1 - 6.7e-05 22.8 0.8 6.7e-05 22.8 0.8 3.0 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDO69872.1 - 0.00014 21.7 5.4 0.002 18.0 0.3 3.1 3 0 0 3 3 3 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CDO69872.1 - 0.00017 21.2 0.4 0.00017 21.2 0.4 2.7 3 0 0 3 3 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CDO69872.1 - 0.00035 20.4 2.2 0.00035 20.4 2.2 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO69872.1 - 0.00037 20.3 0.4 0.00037 20.3 0.4 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDO69872.1 - 0.0014 18.6 4.7 0.0022 18.0 0.1 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CDO69872.1 - 0.0047 16.8 4.2 0.02 14.7 0.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDO69872.1 - 0.012 15.4 0.6 0.012 15.4 0.6 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Zf_RING PF16744.5 CDO69872.1 - 0.19 11.9 0.7 11 6.2 0.3 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger RINGv PF12906.7 CDO69872.1 - 0.77 9.9 3.6 0.26 11.4 0.4 1.8 2 0 0 2 2 1 0 RING-variant domain FANCL_C PF11793.8 CDO69872.1 - 1.4 9.1 5.9 2.7 8.2 0.2 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain PSS PF03034.15 CDO69873.1 - 7.9e-86 288.2 10.1 1.2e-85 287.6 10.1 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase TctB PF07331.11 CDO69873.1 - 0.11 12.7 2.6 0.13 12.5 0.4 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family zf-LYAR PF08790.11 CDO69874.1 - 1.2 9.2 5.5 0.38 10.7 0.6 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger TANGO2 PF05742.12 CDO69875.1 - 7.2e-51 173.7 0.0 9e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Actin PF00022.19 CDO69876.1 - 1e-36 126.5 0.0 2.2e-35 122.1 0.0 1.9 1 1 0 1 1 1 1 Actin Usg PF06233.12 CDO69876.1 - 0.1 12.8 1.1 4.2 7.6 0.5 2.5 2 0 0 2 2 2 0 Usg-like family CCDC85 PF10226.9 CDO69876.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 CCDC85 family Kin17_mid PF10357.9 CDO69878.1 - 6.6e-51 171.5 1.3 6.6e-51 171.5 1.3 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 CDO69878.1 - 0.00032 21.0 5.8 0.00071 19.9 5.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDO69878.1 - 0.003 17.8 5.0 0.0059 16.9 5.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDO69878.1 - 0.26 11.6 3.8 0.13 12.6 1.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DASH_Ask1 PF08655.10 CDO69879.1 - 9.8e-25 86.2 0.3 1.6e-24 85.5 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 DUF2407 PF10302.9 CDO69880.1 - 1.6e-20 73.6 0.0 2.9e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.6 CDO69880.1 - 9e-18 64.8 8.2 1.9e-15 57.3 8.2 3.1 1 1 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 CDO69880.1 - 4.3e-07 29.6 0.0 7.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CDO69880.1 - 0.021 14.9 0.0 0.22 11.7 0.0 2.5 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like VIT1 PF01988.19 CDO69880.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 VIT family IBN_N PF03810.19 CDO69881.1 - 6.9e-11 41.9 0.0 5.7e-09 35.8 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.12 CDO69881.1 - 6.1e-06 26.1 0.5 0.0031 17.3 0.1 3.1 2 1 0 2 2 2 2 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 CDO69881.1 - 0.00022 21.5 0.4 0.04 14.3 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats RTP1_C1 PF10363.9 CDO69881.1 - 0.0017 18.5 0.1 0.02 15.1 0.1 2.9 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 CDO69881.1 - 0.023 15.3 0.0 7.4 7.2 0.0 3.1 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Xpo1 PF08389.12 CDO69881.1 - 0.03 14.4 1.4 0.71 9.9 0.0 3.8 4 1 0 4 4 4 0 Exportin 1-like protein MIF4G_like PF09088.11 CDO69881.1 - 0.036 13.8 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 MIF4G like HEAT_EZ PF13513.6 CDO69881.1 - 0.038 14.5 0.3 0.68 10.5 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 CDO69881.1 - 0.093 13.0 0.2 62 4.3 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat BUD22 PF09073.10 CDO69881.1 - 0.8 9.0 6.4 1.6 8.0 6.4 1.4 1 0 0 1 1 1 0 BUD22 Oxidored_molyb PF00174.19 CDO69882.1 - 2.9e-35 121.4 0.1 2.6e-33 115.1 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CDO69882.1 - 1.3e-10 41.4 0.1 2.5e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain TAF PF02969.17 CDO69883.1 - 3.9e-24 84.6 0.2 7.6e-24 83.7 0.2 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 CDO69883.1 - 2.5e-15 56.6 0.1 5.2e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 CDO69883.1 - 2.6e-06 27.8 0.3 5.4e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CDO69883.1 - 0.04 13.9 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 CDO69883.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CDO69883.1 - 0.091 12.8 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 CDO69883.1 - 0.16 12.4 0.1 0.33 11.3 0.1 1.5 1 0 0 1 1 1 0 CENP-S protein Nup192 PF11894.8 CDO69883.1 - 0.28 8.2 0.0 0.33 8.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 F-box-like PF12937.7 CDO69884.1 - 4.4e-06 26.5 0.3 8.6e-06 25.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO69884.1 - 1.1e-05 25.1 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CDO69884.1 - 0.00031 20.6 0.1 0.00073 19.4 0.1 1.6 1 0 0 1 1 1 1 F-box zf-C2H2_4 PF13894.6 CDO69886.1 - 5.6e-05 23.6 0.4 0.85 10.6 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CDO69886.1 - 0.0019 18.6 4.1 0.11 13.0 0.0 3.2 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO69886.1 - 0.014 15.8 5.0 0.25 11.8 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 CDO69886.1 - 0.051 13.3 1.4 0.051 13.3 1.4 2.3 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Ebp2 PF05890.12 CDO69887.1 - 1.3e-87 293.8 9.9 1.3e-87 293.8 9.9 1.7 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DRMBL PF07522.14 CDO69889.1 - 5.8e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CDO69889.1 - 0.00075 19.1 0.5 0.0079 15.7 0.5 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Mus7 PF09462.10 CDO69890.1 - 3.8e-58 197.8 0.0 1.6e-57 195.7 0.0 1.8 1 1 0 1 1 1 1 Mus7/MMS22 family Sugar_tr PF00083.24 CDO69891.1 - 2.4e-18 66.2 12.2 1.2e-15 57.3 4.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDO69891.1 - 1.8e-16 60.0 47.5 1.3e-11 44.0 30.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO69892.1 - 1.9e-17 63.3 12.9 3.1e-17 62.6 12.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO69892.1 - 5.9e-16 58.3 37.9 1.5e-15 57.0 37.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO69893.1 - 6.7e-20 71.4 14.5 1.1e-16 60.8 4.1 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 CDO69893.1 - 2.2e-17 63.1 65.3 9.2e-16 57.7 40.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Avl9 PF09794.9 CDO69895.1 - 4.2e-130 433.8 0.0 5.5e-130 433.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 CDO69895.1 - 4.6e-09 36.3 0.9 9.5e-06 25.4 0.9 3.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 CDO69895.1 - 1.9e-08 34.2 0.0 0.0035 17.3 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis Glyco_hydro_43 PF04616.14 CDO69896.1 - 1.2e-35 123.2 1.1 2.2e-35 122.4 1.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.14 CDO69897.1 - 5.4e-25 88.3 0.2 6.8e-25 87.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ApbA_C PF08546.11 CDO69898.1 - 6.3e-27 94.2 0.0 9.2e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CDO69898.1 - 0.0002 21.0 0.0 0.00041 20.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Drf_DAD PF06345.11 CDO69898.1 - 0.17 12.0 0.1 0.52 10.4 0.1 1.8 1 0 0 1 1 1 0 DRF Autoregulatory Domain DUF3421 PF11901.8 CDO69899.1 - 7.9e-24 83.9 0.4 6.9e-21 74.4 0.1 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) ABA_WDS PF02496.16 CDO69899.1 - 0.011 16.1 0.7 0.034 14.6 0.7 1.8 1 0 0 1 1 1 0 ABA/WDS induced protein DUF2076 PF09849.9 CDO69899.1 - 0.03 14.4 3.1 0.044 13.8 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF1974 PF09317.11 CDO69899.1 - 0.15 11.6 0.1 0.22 11.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) SARAF PF06682.12 CDO69899.1 - 1.8 8.1 6.1 2.5 7.7 6.1 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PIF1 PF05970.14 CDO69901.1 - 9.9e-53 179.6 0.0 2.8e-50 171.5 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.6 CDO69901.1 - 5.2e-36 124.7 0.1 1e-35 123.7 0.1 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 CDO69901.1 - 0.041 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CDO69902.1 - 6e-119 392.3 0.0 6.6e-20 71.5 0.0 9.9 9 1 1 10 10 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CDO69902.1 - 1.2e-50 170.1 10.8 2.2e-19 69.6 0.0 7.5 7 0 0 7 7 6 3 Midasin AAA lid domain AAA_3 PF07726.11 CDO69902.1 - 8.2e-26 90.4 0.0 1.4e-07 31.4 0.0 8.1 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 CDO69902.1 - 9e-26 90.0 0.0 3.8e-25 88.0 0.0 2.2 2 0 0 2 2 1 1 Midasin AAA lid domain AAA PF00004.29 CDO69902.1 - 2.3e-25 89.6 0.1 0.00016 22.1 0.0 7.3 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDO69902.1 - 2.5e-20 73.6 15.8 0.00024 21.5 0.2 9.0 7 1 0 7 7 7 5 AAA ATPase domain AAA_7 PF12775.7 CDO69902.1 - 3.4e-20 72.3 0.2 0.00055 19.5 0.0 6.7 6 0 0 6 6 6 3 P-loop containing dynein motor region AAA_22 PF13401.6 CDO69902.1 - 2.9e-17 63.2 0.2 0.0034 17.7 0.0 6.9 6 0 0 6 6 6 2 AAA domain Dynein_heavy PF03028.15 CDO69902.1 - 9.4e-17 61.2 0.0 0.011 15.9 0.0 6.9 7 0 0 7 7 6 4 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 CDO69902.1 - 2.2e-16 59.7 0.0 0.053 12.5 0.1 7.5 9 0 0 9 9 7 5 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 CDO69902.1 - 1.7e-15 57.1 0.0 0.052 13.3 0.0 6.4 7 0 0 7 7 6 4 Sigma-54 interaction domain AAA_18 PF13238.6 CDO69902.1 - 1.1e-13 51.8 5.1 0.048 14.2 0.0 7.7 8 0 0 8 8 7 3 AAA domain AAA_14 PF13173.6 CDO69902.1 - 8.1e-13 48.6 0.0 0.049 13.7 0.0 6.9 8 0 0 8 8 6 3 AAA domain TsaE PF02367.17 CDO69902.1 - 1.8e-11 44.1 1.3 0.9 9.6 0.0 6.7 7 0 0 7 7 7 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CDO69902.1 - 2.4e-10 40.4 0.4 0.035 13.8 0.1 6.2 5 1 0 5 5 5 1 AAA domain Mg_chelatase PF01078.21 CDO69902.1 - 2.8e-10 39.9 1.0 0.64 9.4 0.0 8.0 9 0 0 9 9 8 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CDO69902.1 - 5.4e-10 39.9 0.1 0.37 11.3 0.1 6.2 6 0 0 6 6 5 2 ABC transporter RNA_helicase PF00910.22 CDO69902.1 - 6.1e-09 36.2 0.2 3.7 8.0 0.0 6.2 7 0 0 7 7 5 0 RNA helicase T2SSE PF00437.20 CDO69902.1 - 1.8e-08 33.8 0.9 0.11 11.6 0.0 5.7 6 0 0 6 6 6 2 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 CDO69902.1 - 2.9e-08 33.9 0.3 0.069 13.3 0.0 5.4 6 0 0 6 6 4 2 Sigma-54 interaction domain Rad17 PF03215.15 CDO69902.1 - 3e-08 33.8 1.9 0.15 11.9 0.0 5.7 6 0 0 6 6 5 1 Rad17 P-loop domain AAA_28 PF13521.6 CDO69902.1 - 5.4e-08 33.3 9.1 1 9.6 0.0 7.1 8 0 0 8 8 5 2 AAA domain AAA_33 PF13671.6 CDO69902.1 - 2.7e-07 30.8 0.1 2.7 8.1 0.0 6.1 5 0 0 5 5 5 1 AAA domain RuvB_N PF05496.12 CDO69902.1 - 3.4e-07 30.1 0.8 1.3 8.8 0.0 5.5 5 0 0 5 5 5 2 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CDO69902.1 - 4e-07 30.1 1.3 1.9 8.4 0.0 5.2 4 0 0 4 4 4 2 NACHT domain AAA_8 PF12780.7 CDO69902.1 - 1.3e-06 27.9 0.1 0.012 14.9 0.0 4.7 5 0 0 5 5 5 1 P-loop containing dynein motor region D4 AAA_29 PF13555.6 CDO69902.1 - 1.5e-06 27.9 1.3 5 6.9 0.1 6.1 6 0 0 6 6 6 0 P-loop containing region of AAA domain DUF815 PF05673.13 CDO69902.1 - 1.7e-05 24.1 0.0 3.2 6.9 0.0 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF815) AAA_19 PF13245.6 CDO69902.1 - 1.7e-05 25.2 7.7 0.99 9.7 0.1 6.1 7 0 0 7 7 6 1 AAA domain ATPase_2 PF01637.18 CDO69902.1 - 1.9e-05 24.7 0.0 0.087 12.7 0.0 4.5 5 0 0 5 5 4 1 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 CDO69902.1 - 4.4e-05 23.3 0.9 1.2 8.9 0.0 4.6 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 CDO69902.1 - 0.00013 21.6 7.6 5 6.7 0.2 6.1 6 0 0 6 6 6 0 AAA domain Zeta_toxin PF06414.12 CDO69902.1 - 0.00016 21.0 0.0 6.9 5.9 0.0 5.8 6 0 0 6 6 6 0 Zeta toxin RsgA_GTPase PF03193.16 CDO69902.1 - 0.00016 21.6 0.4 4.9 7.0 0.0 4.7 4 0 0 4 4 4 0 RsgA GTPase SRP54 PF00448.22 CDO69902.1 - 0.00044 19.9 1.4 7.7 6.1 0.0 4.6 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 CDO69902.1 - 0.00055 20.0 0.4 5.5 7.1 0.1 5.3 6 0 0 6 6 6 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 CDO69902.1 - 0.0013 18.5 0.0 5.3 6.7 0.0 4.2 4 0 0 4 4 3 0 IstB-like ATP binding protein CbiA PF01656.23 CDO69902.1 - 0.0016 18.5 0.2 1.4 8.9 0.0 4.0 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 CDO69902.1 - 0.0017 18.1 0.0 9 6.0 0.0 4.8 5 0 0 5 5 4 0 AAA domain TniB PF05621.11 CDO69902.1 - 0.0045 16.4 0.0 13 5.1 0.0 4.5 4 0 0 4 4 4 0 Bacterial TniB protein MeaB PF03308.16 CDO69902.1 - 0.0065 15.5 0.2 13 4.7 0.0 3.4 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 CDO69902.1 - 0.0076 16.2 6.5 11 5.9 0.1 5.3 7 0 0 7 7 4 0 NTPase Roc PF08477.13 CDO69902.1 - 0.0079 16.4 1.1 50 4.2 0.0 4.5 5 0 0 5 5 4 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 CDO69902.1 - 0.011 15.4 0.5 36 4.0 0.0 4.4 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family dNK PF01712.19 CDO69902.1 - 0.012 15.4 2.9 21 4.9 0.0 4.3 5 0 0 5 5 4 0 Deoxynucleoside kinase Viral_helicase1 PF01443.18 CDO69902.1 - 0.013 15.2 0.1 11 5.6 0.0 3.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CDO69902.1 - 0.036 14.1 0.0 6.9 6.6 0.0 3.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CDO69902.1 - 0.2 11.4 12.4 34 4.1 0.0 5.8 6 0 0 6 6 4 0 AAA domain CLP1_P PF16575.5 CDO69902.1 - 2.1 8.1 4.3 2.5 7.8 0.1 3.2 4 0 0 4 4 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Flavoprotein PF02441.19 CDO69903.1 - 5.9e-49 165.8 0.0 6.6e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein LRR_6 PF13516.6 CDO69904.1 - 3.4e-15 54.7 7.4 0.1 12.7 0.0 7.1 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 CDO69904.1 - 0.00014 21.9 0.1 1e+02 4.1 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 CDO69904.1 - 0.0038 17.6 9.1 6 7.4 0.4 5.6 4 2 3 7 7 7 2 Leucine Rich repeats (2 copies) BSP_II PF05432.11 CDO69904.1 - 0.16 11.7 3.4 0.24 11.1 3.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4713 PF15831.5 CDO69904.1 - 0.22 12.0 0.0 0.42 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) DUF3605 PF12239.8 CDO69905.1 - 2.2e-29 102.7 0.0 1.3e-19 71.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) HIT PF01230.23 CDO69905.1 - 0.17 12.6 0.0 0.29 11.9 0.0 1.4 1 0 0 1 1 1 0 HIT domain Tyrosinase PF00264.20 CDO69906.1 - 2e-57 195.0 0.4 2e-57 195.0 0.4 2.3 2 1 1 3 3 3 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 CDO69906.1 - 2.5e-29 102.4 0.0 4.6e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Rad60-SLD PF11976.8 CDO69907.1 - 5.4e-10 39.0 0.0 1.5e-05 24.7 0.1 3.0 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like TmoB PF06234.12 CDO69907.1 - 0.54 10.4 1.7 12 6.0 0.2 3.0 2 1 1 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) EMP24_GP25L PF01105.24 CDO69908.1 - 0.0075 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Bombesin PF02044.17 CDO69910.1 - 4.5 7.6 5.4 9 6.6 5.4 1.5 1 0 0 1 1 1 0 Bombesin-like peptide p450 PF00067.22 CDO69911.1 - 3.9e-52 177.6 0.0 4.4e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pex24p PF06398.11 CDO69912.1 - 1.3e-14 54.0 0.4 1.7e-14 53.6 0.4 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DDE_Tnp_4 PF13359.6 CDO69913.1 - 9.1e-23 80.7 0.0 1.6e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO69913.1 - 7.3e-06 25.8 0.0 3.9e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO69913.1 - 3.8e-05 23.4 0.0 0.00022 20.9 0.1 2.0 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO69913.1 - 0.00027 21.2 0.0 0.00058 20.2 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain UVR PF02151.19 CDO69913.1 - 0.53 10.1 2.3 1.1 9.1 2.3 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif Myb_DNA-bind_4 PF13837.6 CDO69914.1 - 6.1e-09 36.1 0.2 1.2e-08 35.3 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CDO69914.1 - 1.1e-08 35.9 0.1 1.8e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO69914.1 - 0.0009 19.3 0.0 0.0035 17.4 0.0 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Tub_N PF16322.5 CDO69914.1 - 0.0042 17.5 1.4 0.0078 16.6 1.4 1.4 1 0 0 1 1 1 1 Tubby N-terminal Myc_N PF01056.18 CDO69914.1 - 0.0043 17.0 1.3 0.0071 16.3 1.3 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Myb_DNA-binding PF00249.31 CDO69914.1 - 0.0093 16.1 0.3 0.021 15.0 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TAP42 PF04177.12 CDO69914.1 - 0.04 13.0 0.9 0.063 12.4 0.9 1.3 1 0 0 1 1 1 0 TAP42-like family TAL_effector PF03377.13 CDO69914.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 TAL effector repeat Myb_DNA-bind_6 PF13921.6 CDO69914.1 - 0.1 12.8 0.2 0.27 11.5 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain RRN3 PF05327.11 CDO69914.1 - 0.19 10.3 2.9 0.24 9.9 2.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CDO69914.1 - 0.23 9.5 3.5 0.34 9.0 3.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 CDO69914.1 - 2.6 8.5 11.8 5.2 7.5 11.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LAT PF15234.6 CDO69914.1 - 3.7 7.2 9.0 3.7 7.2 7.9 1.5 1 1 0 1 1 1 0 Linker for activation of T-cells RhoGEF PF00621.20 CDO69915.1 - 1.8e-35 122.8 0.1 4.3e-35 121.6 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain Laminin_II PF06009.12 CDO69915.1 - 0.056 13.5 3.4 2.8 8.0 1.2 3.1 2 0 0 2 2 2 0 Laminin Domain II ArfA PF03889.13 CDO69915.1 - 0.24 10.9 1.4 0.49 9.9 1.4 1.5 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A KxDL PF10241.9 CDO69915.1 - 9.4 6.6 9.2 20 5.5 5.3 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein Myb_DNA-binding PF00249.31 CDO69916.1 - 5.9e-22 77.6 4.0 5.3e-11 42.5 0.1 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDO69916.1 - 1e-18 67.3 0.9 3.7e-13 49.5 0.3 4.2 3 1 2 5 5 5 2 Myb-like DNA-binding domain Rap1_C PF11626.8 CDO69916.1 - 0.0085 16.2 0.1 0.37 10.9 0.1 2.6 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 CDO69916.1 - 0.065 13.6 4.9 0.34 11.3 0.5 3.4 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 CDO69916.1 - 0.24 11.6 0.9 11 6.3 0.1 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Amidohydro_3 PF07969.11 CDO69917.1 - 5.8e-10 39.2 6.4 7.6e-07 28.9 0.0 3.2 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_1 PF01979.20 CDO69917.1 - 2.4e-08 33.7 0.0 1.3e-05 24.7 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Syntaxin PF00804.25 CDO69918.1 - 0.00012 21.9 0.8 0.0011 18.6 0.6 2.2 2 0 0 2 2 2 1 Syntaxin KASH_CCD PF14662.6 CDO69918.1 - 0.00072 19.4 1.7 0.62 9.9 0.0 2.2 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH Cnn_1N PF07989.11 CDO69918.1 - 0.0016 18.5 2.1 0.0028 17.8 1.3 1.8 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 Uso1_p115_C PF04871.13 CDO69918.1 - 0.017 15.5 2.5 0.017 15.5 2.5 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4351 PF14261.6 CDO69918.1 - 0.02 15.0 0.8 0.051 13.7 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) DivIC PF04977.15 CDO69918.1 - 0.064 13.0 6.6 4.9 7.0 3.0 2.5 2 0 0 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 CDO69918.1 - 0.067 13.3 9.6 0.087 12.9 0.0 3.1 2 1 1 3 3 3 0 Basic region leucine zipper TMF_DNA_bd PF12329.8 CDO69918.1 - 0.12 12.4 6.3 6.3 6.9 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Herpes_UL6 PF01763.16 CDO69918.1 - 0.2 10.1 3.5 1.3 7.4 0.1 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF4446 PF14584.6 CDO69918.1 - 0.27 11.2 1.0 9.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Fungal_TACC PF12709.7 CDO69918.1 - 0.31 11.5 2.8 23 5.5 0.0 2.3 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TSC22 PF01166.18 CDO69918.1 - 0.5 10.7 5.5 11 6.4 2.6 2.5 2 1 0 2 2 2 0 TSC-22/dip/bun family End3 PF12761.7 CDO69918.1 - 0.57 10.3 5.4 0.1 12.8 1.6 1.6 2 0 0 2 2 1 0 Actin cytoskeleton-regulatory complex protein END3 Atg14 PF10186.9 CDO69918.1 - 0.59 9.2 3.2 0.88 8.6 3.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 CDO69918.1 - 0.73 10.3 7.5 19 5.8 0.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 CDO69918.1 - 0.77 9.9 12.2 3.2 7.9 0.0 2.8 3 1 0 3 3 2 0 bZIP transcription factor HALZ PF02183.18 CDO69918.1 - 1.6 9.0 5.7 0.59 10.4 0.4 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper BRE1 PF08647.11 CDO69918.1 - 1.9 8.6 8.6 22 5.2 8.6 2.2 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 CDO69918.1 - 5.1 6.4 6.9 0.25 10.6 1.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 CDO69918.1 - 7.4 7.1 14.6 2.7 8.5 0.1 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region Lactamase_B_4 PF13691.6 CDO69919.1 - 1.5e-07 31.0 0.0 2.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CDO69919.1 - 0.00039 20.0 0.1 0.36 10.3 0.0 3.3 2 1 0 2 2 2 2 Beta-lactamase superfamily domain THOC7 PF05615.13 CDO69920.1 - 3.3e-32 111.6 5.8 3.3e-32 111.6 5.8 2.3 1 1 1 2 2 2 2 Tho complex subunit 7 PAM2 PF07145.15 CDO69920.1 - 0.0086 15.7 0.1 0.023 14.4 0.1 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region PIN_8 PF18476.1 CDO69920.1 - 0.027 14.3 6.6 0.05 13.5 6.6 1.4 1 0 0 1 1 1 0 PIN like domain FapA PF03961.13 CDO69920.1 - 0.038 12.6 7.1 0.057 12.0 7.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 CDO69920.1 - 0.044 11.7 1.5 0.054 11.4 1.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ran-binding PF05508.11 CDO69920.1 - 0.061 12.3 5.8 0.094 11.7 5.8 1.2 1 0 0 1 1 1 0 RanGTP-binding protein DUF842 PF05811.13 CDO69920.1 - 0.069 12.8 1.3 0.17 11.6 1.2 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Biopterin_H PF00351.21 CDO69920.1 - 0.13 11.3 1.1 0.65 9.0 1.0 1.8 1 1 1 2 2 2 0 Biopterin-dependent aromatic amino acid hydroxylase DUF4407 PF14362.6 CDO69920.1 - 0.44 9.8 6.5 0.73 9.1 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CDO69920.1 - 0.6 10.2 5.8 0.84 9.7 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fungal_TACC PF12709.7 CDO69920.1 - 1 9.8 7.9 0.72 10.3 3.7 2.3 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins zf-C4H2 PF10146.9 CDO69920.1 - 1.8 8.8 13.4 5.9 7.1 13.4 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein TMPIT PF07851.13 CDO69920.1 - 2.9 7.1 4.7 4.1 6.6 4.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 CDO69920.1 - 3.2 7.8 19.1 0.64 10.0 9.8 2.5 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlqD PF11068.8 CDO69920.1 - 6.8 7.1 14.0 2.8 8.3 7.2 2.3 1 1 1 2 2 2 0 YlqD protein DUF202 PF02656.15 CDO69921.1 - 9.7e-14 51.6 5.6 1.3e-13 51.1 3.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CX9C PF16860.5 CDO69922.1 - 0.002 18.1 10.6 0.33 11.0 4.3 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CDO69922.1 - 0.0042 17.2 10.1 0.011 15.8 3.5 2.5 2 0 0 2 2 2 1 CHCH domain DB PF01682.19 CDO69922.1 - 0.16 12.3 6.3 12 6.3 0.3 2.1 1 1 1 2 2 2 0 DB module DUF2655 PF10848.8 CDO69922.1 - 0.91 9.9 4.4 4.2 7.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2655) Pet191_N PF10203.9 CDO69922.1 - 2.2 8.7 9.7 33 4.9 0.5 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 CDO69922.1 - 7.5 6.9 10.6 0.83 9.9 4.1 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF498 PF04430.14 CDO69924.1 - 3.8e-15 55.9 0.2 1.5e-14 54.0 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) SANT_DAMP1_like PF16282.5 CDO69925.1 - 8e-27 93.3 2.7 2e-26 92.0 2.7 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Lip_prot_lig_C PF10437.9 CDO69925.1 - 0.00012 22.0 0.0 0.0006 19.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 CDO69925.1 - 0.01 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CP_ATPgrasp_2 PF14403.6 CDO69925.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 MWFE PF15879.5 CDO69926.1 - 2.7e-17 62.7 1.0 3.3e-17 62.4 1.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit DUF4218 PF13960.6 CDO69927.1 - 0.0022 17.6 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) COG6 PF06419.11 CDO69928.1 - 0.24 9.6 0.3 0.34 9.1 0.3 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 WD40 PF00400.32 CDO69929.1 - 1.5e-36 123.7 34.5 8.9e-07 29.5 2.1 12.0 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO69929.1 - 3e-19 69.1 2.6 0.004 17.4 0.1 7.7 4 2 3 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 CDO69929.1 - 3.2e-08 33.7 0.1 8.9e-08 32.2 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CDO69929.1 - 0.00045 20.7 1.8 0.0025 18.2 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain Coatomer_WDAD PF04053.14 CDO69929.1 - 0.00067 18.8 0.0 2.9 6.8 0.0 3.3 2 1 0 3 3 3 2 Coatomer WD associated region Ge1_WD40 PF16529.5 CDO69929.1 - 0.0019 17.2 0.4 4 6.3 0.0 4.3 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CDO69929.1 - 0.014 14.8 3.4 0.46 9.8 0.2 3.8 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 CDO69929.1 - 0.019 14.3 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Goodbye PF17109.5 CDO69929.1 - 0.039 14.4 0.2 0.17 12.4 0.0 2.0 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 CDO69929.1 - 0.077 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.13 CDO69929.1 - 0.16 12.7 0.9 0.63 10.8 0.7 2.1 3 0 0 3 3 2 0 Occludin homology domain CENP-K PF11802.8 CDO69929.1 - 0.3 10.6 1.9 0.55 9.8 1.1 1.7 2 0 0 2 2 2 0 Centromere-associated protein K Bombesin PF02044.17 CDO69930.1 - 0.42 10.8 2.7 1.6 9.0 2.7 2.1 1 0 0 1 1 1 0 Bombesin-like peptide P16-Arc PF04699.14 CDO69932.1 - 6.9e-48 162.9 0.0 8.1e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 CDO69932.1 - 0.096 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family WD40 PF00400.32 CDO69933.1 - 3.8e-08 33.9 7.3 0.007 17.2 0.5 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.7 CDO69933.1 - 1.8e-07 30.9 0.1 3.6e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO69933.1 - 1.4e-06 28.0 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 CDO69933.1 - 0.00055 20.2 0.1 3.2 8.1 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain UIM PF02809.20 CDO69933.1 - 2.2 8.4 8.9 0.045 13.7 1.4 2.2 3 0 0 3 3 3 0 Ubiquitin interaction motif Terpene_synth_C PF03936.16 CDO69934.1 - 0.001 18.5 0.0 0.022 14.1 0.0 2.3 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain CrgA PF06781.12 CDO69936.1 - 0.041 13.9 0.4 0.16 12.0 0.1 2.0 1 1 1 2 2 2 0 Cell division protein CrgA PEN-2 PF10251.9 CDO69936.1 - 0.17 12.3 0.2 0.49 10.8 0.0 1.7 1 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Tetraspanin PF00335.20 CDO69936.1 - 0.18 11.5 0.1 0.26 11.0 0.1 1.1 1 0 0 1 1 1 0 Tetraspanin family Sporozoite_P67 PF05642.11 CDO69936.1 - 2.9 5.8 4.9 3.7 5.5 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen p450 PF00067.22 CDO69938.1 - 3.1e-54 184.5 0.0 2.1e-30 105.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF3671 PF12420.8 CDO69939.1 - 0.003 17.6 0.4 3.2 7.9 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function RTA1 PF04479.13 CDO69939.1 - 0.0093 15.6 0.7 0.0093 15.6 0.7 1.8 1 1 1 2 2 2 1 RTA1 like protein DUF3397 PF11877.8 CDO69939.1 - 0.47 10.7 11.1 0.18 12.0 2.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3397) DUF2070 PF09843.9 CDO69939.1 - 6.2 5.0 8.1 0.29 9.4 2.4 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) BPD_transp_1 PF00528.22 CDO69939.1 - 7.8 6.2 13.5 4.6 6.9 0.0 3.0 3 1 0 3 3 3 0 Binding-protein-dependent transport system inner membrane component SNase PF00565.17 CDO69941.1 - 1.8e-16 60.5 0.0 2.9e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue HTH_Tnp_Tc5 PF03221.16 CDO69941.1 - 0.039 14.0 0.0 0.32 11.1 0.0 2.4 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain Flavodoxin_1 PF00258.25 CDO69942.1 - 2.1e-28 99.3 0.0 4.5e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 CDO69942.1 - 8.6e-19 68.0 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CDO69942.1 - 1.4e-14 54.6 0.0 3.3e-14 53.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 CDO69942.1 - 0.077 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Beta-lactamase PF00144.24 CDO69943.1 - 5.6e-41 140.9 0.5 9.7e-41 140.1 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 CDO69943.1 - 1.8e-05 25.1 0.1 6.3e-05 23.4 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) AvrPto PF11592.8 CDO69943.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto SNF2_N PF00176.23 CDO69944.1 - 4.7e-50 170.3 1.1 2.6e-49 167.8 1.1 1.9 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDO69944.1 - 6.2e-18 65.2 0.0 1.5e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO69944.1 - 5.5e-05 23.2 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CDO69944.1 - 0.00036 20.3 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase FYVE PF01363.21 CDO69944.1 - 0.064 13.4 1.1 0.16 12.1 1.1 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.25 CDO69944.1 - 0.069 13.0 2.0 0.1 12.5 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO69944.1 - 0.16 11.9 2.0 0.48 10.4 2.0 1.8 1 1 0 1 1 1 0 zinc-RING finger domain TFIIF_alpha PF05793.12 CDO69944.1 - 0.25 9.9 11.8 0.38 9.3 11.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C3HC4_4 PF15227.6 CDO69944.1 - 0.48 10.6 4.1 0.16 12.1 0.9 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CDO69944.1 - 1.2 9.5 3.6 0.61 10.5 0.7 2.0 2 0 0 2 2 2 0 Ring finger domain adh_short PF00106.25 CDO69945.1 - 1e-25 90.4 0.3 1.5e-25 89.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69945.1 - 6.7e-20 71.7 0.9 8.4e-20 71.3 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO69945.1 - 1.7e-07 31.3 0.3 5.9e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 CDO69945.1 - 3.4e-07 30.3 3.1 1.2e-06 28.6 0.2 2.2 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 CDO69945.1 - 8.5e-05 22.2 0.1 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 CDO69945.1 - 0.00055 20.2 1.7 0.002 18.4 0.1 2.3 2 1 0 2 2 2 1 TrkA-N domain ADH_zinc_N PF00107.26 CDO69947.1 - 1.9e-16 60.2 0.0 3.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO69947.1 - 2.4e-11 43.5 0.0 5.2e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDO69947.1 - 7.5e-06 27.0 0.0 1.2e-05 26.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CDO69947.1 - 0.16 11.9 0.1 0.37 10.7 0.1 1.6 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 CDO69948.1 - 6.4e-16 58.5 0.1 1.4e-15 57.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO69948.1 - 6.1e-11 42.2 0.1 7.2e-10 38.7 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDO69948.1 - 6e-08 33.8 0.0 1.2e-07 32.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CDO69948.1 - 0.0045 16.5 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 CDO69949.1 - 4.3e-15 55.8 0.0 7.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO69949.1 - 2.6e-09 36.9 0.0 5.4e-09 35.9 0.0 1.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDO69949.1 - 1.4e-06 29.4 0.0 2.5e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CDO69949.1 - 0.11 12.4 0.3 0.77 9.7 0.3 2.0 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Adaptin_N PF01602.20 CDO69950.1 - 1.3e-138 462.9 5.7 1.6e-138 462.5 5.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDO69950.1 - 3.3e-60 202.8 5.4 2.7e-59 199.8 0.7 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDO69950.1 - 2e-16 60.1 6.3 3.9e-08 33.6 0.1 6.4 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 CDO69950.1 - 2e-06 27.6 16.7 0.00025 21.0 0.1 6.3 8 0 0 8 8 8 3 HEAT repeat Arm PF00514.23 CDO69950.1 - 2.8e-05 24.0 5.1 0.092 12.8 0.0 5.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 CDO69950.1 - 0.00036 20.2 0.1 0.16 11.5 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 CDO69950.1 - 0.00044 20.7 9.4 0.33 11.5 0.1 6.5 6 2 2 8 8 8 1 HEAT-like repeat RTP1_C1 PF10363.9 CDO69950.1 - 0.00059 20.0 0.9 0.35 11.1 0.0 3.9 3 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 CDO69950.1 - 0.026 14.3 1.3 0.39 10.5 0.1 3.1 3 1 0 3 3 3 0 TATA-binding protein interacting (TIP20) GlutR_dimer PF00745.20 CDO69950.1 - 0.086 13.3 0.1 0.8 10.2 0.1 2.7 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain 2OG-FeII_Oxy_3 PF13640.6 CDO69951.1 - 6.9e-10 39.7 0.0 1.6e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNA_pol PF00940.19 CDO69952.1 - 1.2e-181 604.0 0.0 1.7e-181 603.6 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CDO69952.1 - 2e-97 326.6 0.4 2e-97 326.6 0.4 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 CDO69952.1 - 0.00014 22.0 0.2 0.00034 20.8 0.2 1.7 1 0 0 1 1 1 1 PPR repeat family SUR7 PF06687.12 CDO69953.1 - 3.5e-13 49.7 16.0 1.3e-12 47.8 16.1 1.9 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 CDO69953.1 - 0.0069 16.2 4.0 0.02 14.7 3.7 1.9 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction UPF0182 PF03699.13 CDO69953.1 - 0.29 9.2 1.7 0.37 8.9 1.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Tetraspanin PF00335.20 CDO69953.1 - 3.4 7.3 7.0 0.49 10.1 1.9 1.9 2 0 0 2 2 2 0 Tetraspanin family Histone PF00125.24 CDO69954.1 - 2.3e-18 66.8 0.0 3.1e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDO69954.1 - 1.9e-11 43.5 0.1 1.9e-11 43.5 0.1 2.1 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CDO69954.1 - 0.0063 16.8 0.0 0.0092 16.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aldo_ket_red PF00248.21 CDO69955.1 - 1.4e-52 178.7 0.0 1.8e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CDO69956.1 - 3.9e-40 137.9 0.0 6.7e-21 74.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family IATP PF04568.12 CDO69957.1 - 2.5e-08 34.2 13.8 2.5e-08 34.2 13.8 1.4 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP DUF3573 PF12097.8 CDO69957.1 - 0.0019 17.1 0.8 0.0022 16.9 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) Spc7 PF08317.11 CDO69957.1 - 0.0061 15.5 6.5 0.0061 15.5 6.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein HemX PF04375.14 CDO69957.1 - 0.023 14.0 5.3 0.023 14.0 5.3 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4140 PF13600.6 CDO69957.1 - 0.035 14.5 2.4 0.042 14.3 2.4 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4349 PF14257.6 CDO69957.1 - 0.043 13.3 2.2 0.052 13.0 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) EAP30 PF04157.16 CDO69957.1 - 0.085 12.1 6.0 0.1 11.9 6.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family CRA PF06589.11 CDO69957.1 - 0.11 12.6 3.2 0.15 12.2 3.2 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF4407 PF14362.6 CDO69957.1 - 0.14 11.5 5.5 0.15 11.4 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IFT20 PF14931.6 CDO69957.1 - 0.22 11.7 9.6 0.27 11.4 9.6 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DivIC PF04977.15 CDO69957.1 - 0.3 10.9 9.9 0.38 10.5 9.5 1.4 1 1 0 1 1 1 0 Septum formation initiator Atg14 PF10186.9 CDO69957.1 - 0.33 10.0 6.6 0.33 10.0 6.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP_sub_h PF10775.9 CDO69958.1 - 4.3e-25 87.5 3.1 7.4e-25 86.7 3.1 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h HEM4 PF02602.15 CDO69959.1 - 1e-35 123.2 0.6 1.3e-35 122.8 0.6 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF1708 PF08101.11 CDO69960.1 - 3.1e-19 69.4 0.0 8.6e-16 58.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) Ribosomal_60s PF00428.19 CDO69960.1 - 0.01 16.4 1.2 0.01 16.4 1.2 10.7 5 3 5 10 10 10 0 60s Acidic ribosomal protein RhoGAP PF00620.27 CDO69960.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 RhoGAP domain Pilin_N PF07790.11 CDO69961.1 - 0.0023 18.8 0.1 0.0043 17.9 0.1 1.5 1 1 0 1 1 1 1 Archaeal Type IV pilin, N-terminal p450 PF00067.22 CDO69964.1 - 2.2e-32 112.4 0.0 3.2e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Lyase_1 PF00206.20 CDO69964.1 - 7e-23 81.5 0.0 9.5e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CDO69964.1 - 3.2e-06 27.6 0.1 3.4e-05 24.3 0.0 2.8 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus PigN PF04987.14 CDO69965.1 - 1.3e-117 393.5 21.4 1.6e-117 393.2 21.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CDO69965.1 - 1.7e-11 44.3 2.4 3.3e-09 36.8 1.4 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDO69965.1 - 6.1e-07 29.1 0.1 9e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CDO69965.1 - 5.8e-06 25.9 0.1 1.1e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DAO PF01266.24 CDO69966.1 - 1.3e-63 215.7 3.2 1.5e-63 215.5 3.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CDO69966.1 - 2.6e-06 26.6 0.2 1.1e-05 24.6 0.2 1.8 1 1 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 CDO69966.1 - 2.9e-06 26.7 0.0 0.001 18.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO69966.1 - 6.7e-05 23.0 0.1 0.00015 21.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CDO69966.1 - 0.0027 17.7 0.1 0.028 14.4 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CDO69966.1 - 0.0029 17.9 0.1 0.049 13.9 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 CDO69966.1 - 0.019 14.2 0.1 0.036 13.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 CDO69966.1 - 0.034 14.7 0.1 0.034 14.7 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 CDO69966.1 - 0.11 11.9 0.1 7.9 5.7 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase PS_Dcarbxylase PF02666.15 CDO69967.1 - 2.7e-44 151.1 0.0 3.9e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 CDO69967.1 - 1e-36 126.0 0.0 1.8e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase SRP9-21 PF05486.12 CDO69968.1 - 2.3e-12 47.2 1.7 2.3e-12 47.2 1.7 2.8 1 1 1 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) MSA-2c PF12238.8 CDO69968.1 - 0.0058 16.7 3.0 0.0074 16.3 3.0 1.2 1 0 0 1 1 1 1 Merozoite surface antigen 2c Fe-S_assembly PF04384.13 CDO69968.1 - 0.053 14.1 0.1 0.098 13.3 0.1 1.3 1 0 0 1 1 1 0 Iron-sulphur cluster assembly Mito_carr PF00153.27 CDO69969.1 - 1.2e-46 156.6 0.5 1.8e-15 56.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Glug PF07581.12 CDO69969.1 - 0.15 12.5 0.9 1.7 9.2 0.2 2.6 2 0 0 2 2 2 0 The GLUG motif adh_short PF00106.25 CDO69970.1 - 2.1e-13 50.2 0.7 6.8e-12 45.2 0.7 2.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69970.1 - 4.5e-07 29.7 0.6 0.00015 21.4 0.6 2.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UQ_con PF00179.26 CDO69971.1 - 1.6e-39 134.7 0.0 2.4e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme OTU PF02338.19 CDO69973.1 - 2.2e-14 54.0 0.0 5.6e-14 52.7 0.0 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CDO69973.1 - 0.0075 15.8 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain adh_short PF00106.25 CDO69974.1 - 1.1e-17 64.1 0.0 1.2e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO69974.1 - 5e-14 52.4 0.0 5.6e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO69974.1 - 4.8e-07 29.9 0.1 1.1e-06 28.7 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO69974.1 - 0.00044 19.8 0.0 0.00051 19.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CDO69974.1 - 0.0038 17.1 0.2 0.0053 16.7 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CDO69974.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.5 1 1 1 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CDO69974.1 - 0.021 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 CDO69974.1 - 0.11 13.0 0.0 0.15 12.6 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.8 CDO69974.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.6 CDO69975.1 - 9e-37 126.9 0.2 1.1e-36 126.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO69975.1 - 2.6e-33 115.2 0.1 5e-33 114.2 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CDO69975.1 - 1.3e-09 38.2 0.6 3.7e-09 36.7 0.6 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO69975.1 - 0.0018 17.8 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CDO69975.1 - 0.0034 16.8 0.0 0.0047 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 CDO69975.1 - 0.013 15.4 0.2 0.026 14.4 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CDO69975.1 - 0.021 14.2 0.1 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CDO69975.1 - 0.076 12.1 0.0 0.17 11.0 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.25 CDO69976.1 - 1.9e-69 234.0 0.0 2.6e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO69976.1 - 4e-38 131.2 0.0 6.4e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO69976.1 - 1.1e-06 28.2 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDO69976.1 - 0.004 16.1 0.4 0.0066 15.4 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CDO69976.1 - 0.025 14.2 0.1 0.048 13.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CDO69976.1 - 0.044 13.7 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family KA1 PF02149.19 CDO69977.1 - 2.8e-05 23.8 0.0 5.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 CNH PF00780.22 CDO69978.1 - 2.9e-47 161.6 0.0 4e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 CNH domain PH PF00169.29 CDO69978.1 - 0.064 13.8 0.7 0.68 10.5 0.7 2.5 1 1 0 1 1 1 0 PH domain Integrase_H2C2 PF17921.1 CDO69979.1 - 1.1e-06 28.7 0.4 2.4e-06 27.6 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Mito_carr PF00153.27 CDO69980.1 - 2e-62 207.1 2.6 8.8e-21 73.6 0.3 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_28 PF00295.17 CDO69980.1 - 1.6e-29 103.0 0.1 1.1e-28 100.2 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Ribosomal_S19 PF00203.21 CDO69981.1 - 7.3e-28 96.3 0.0 8.9e-28 96.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DUF3584 PF12128.8 CDO69984.1 - 3.3 5.1 18.3 4.6 4.6 18.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GspH PF12019.8 CDO69984.1 - 3.6 8.1 8.6 62 4.1 0.1 3.8 2 2 1 3 3 3 0 Type II transport protein GspH Ribosomal_S19 PF00203.21 CDO69985.1 - 7.3e-28 96.3 0.0 8.9e-28 96.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 TPPII_N PF12583.8 CDO69986.1 - 5.3 7.6 8.8 9.4 6.8 8.8 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal STE3 PF02076.15 CDO69987.1 - 5e-108 360.7 20.5 5.9e-108 360.5 20.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor SKG6 PF08693.10 CDO69987.1 - 0.2 11.1 5.9 0.51 9.8 0.9 2.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain STE3 PF02076.15 CDO69988.1 - 3.5e-78 262.7 24.3 1.8e-55 188.2 7.3 2.0 1 1 1 2 2 2 2 Pheromone A receptor Pro_CA PF00484.19 CDO69989.1 - 1.9e-12 47.8 0.0 2.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase AidB_N PF18158.1 CDO69990.1 - 0.07 13.1 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Adaptive response protein AidB N-terminal domain MIP PF00230.20 CDO69991.1 - 2.1e-51 174.8 7.1 2.7e-51 174.5 7.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein ZapB PF06005.12 CDO69992.1 - 0.035 14.6 5.0 0.035 14.6 5.0 2.3 2 0 0 2 2 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 CDO69992.1 - 0.13 12.3 2.6 0.51 10.4 2.6 2.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding She9_MDM33 PF05546.11 CDO69992.1 - 0.15 11.8 11.9 1.8 8.3 4.5 2.9 1 1 1 2 2 2 0 She9 / Mdm33 family Golgin_A5 PF09787.9 CDO69992.1 - 0.21 11.0 9.9 0.046 13.2 4.8 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 BMFP PF04380.13 CDO69992.1 - 1.6 9.3 9.2 6.4 7.3 1.4 2.6 2 0 0 2 2 2 0 Membrane fusogenic activity Spc24 PF08286.11 CDO69992.1 - 1.8 8.8 6.2 1.3 9.3 2.5 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YlqD PF11068.8 CDO69992.1 - 2.3 8.6 9.6 2.1 8.7 4.1 2.4 2 0 0 2 2 2 0 YlqD protein OGFr_N PF04664.13 CDO69993.1 - 2.9e-59 200.1 3.3 3.3e-59 199.9 3.3 1.0 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region DUF727 PF05303.12 CDO69995.1 - 2.9e-07 30.5 0.1 2.4e-06 27.6 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF727) Sec1 PF00995.23 CDO69996.1 - 7.3e-124 415.1 0.0 8.4e-124 414.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.12 CDO69997.1 - 5.1e-84 281.5 0.1 8.2e-84 280.9 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CDO69997.1 - 1.9e-25 89.1 0.2 1.9e-25 89.1 0.2 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PhoLip_ATPase_C PF16212.5 CDO69999.1 - 9.5e-75 251.6 27.0 9.5e-75 251.6 27.0 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDO69999.1 - 1.6e-22 79.0 1.1 3.8e-22 77.8 1.1 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CDO69999.1 - 3.3e-12 47.2 3.2 3.4e-07 30.8 0.8 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDO69999.1 - 2e-10 40.6 0.0 2e-09 37.4 0.0 2.6 2 1 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CDO69999.1 - 0.00014 21.4 0.0 0.00014 21.4 0.0 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDO69999.1 - 0.00022 21.0 0.9 0.0049 16.7 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HTH_21 PF13276.6 CDO70000.1 - 0.0022 18.1 0.1 0.0049 17.0 0.0 1.6 2 0 0 2 2 2 1 HTH-like domain DDE_Tnp_ISAZ013 PF07592.11 CDO70000.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Pkinase PF00069.25 CDO70001.1 - 8.7e-08 31.8 0.0 2.3e-07 30.5 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70001.1 - 0.0077 15.5 0.0 0.0096 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3506 PF12014.8 CDO70002.1 - 1.9e-07 31.2 0.0 3.2e-05 24.0 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.33 CDO70002.1 - 3.2e-06 26.9 0.8 9e-06 25.4 0.8 1.8 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO70002.1 - 0.00019 21.3 0.7 0.00019 21.3 0.7 2.0 2 0 0 2 2 2 1 F-box-like zf-RING_11 PF17123.5 CDO70003.1 - 0.00014 21.5 1.9 0.073 12.8 0.0 2.4 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_2 PF13639.6 CDO70003.1 - 0.014 15.7 0.5 2.9 8.3 0.2 2.4 2 0 0 2 2 2 0 Ring finger domain Pam17 PF08566.10 CDO70004.1 - 1.8e-66 223.1 0.0 2.3e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 F-box-like PF12937.7 CDO70005.1 - 0.083 12.8 2.0 0.2 11.6 2.0 1.7 1 0 0 1 1 1 0 F-box-like ATP-synt_ab PF00006.25 CDO70006.1 - 2.5e-63 213.6 0.0 3.9e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDO70006.1 - 5.4e-22 78.1 1.9 1.6e-21 76.6 1.9 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 CDO70006.1 - 0.0051 16.0 0.9 0.012 14.8 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 CDO70006.1 - 0.03 14.2 0.1 0.063 13.2 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 CDO70006.1 - 0.034 14.6 0.0 0.35 11.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CDO70006.1 - 0.037 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 CDO70006.1 - 0.043 14.2 0.1 0.14 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CDO70006.1 - 0.059 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 CDO70006.1 - 0.067 12.5 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 CDO70006.1 - 0.083 13.2 0.7 0.31 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.23 CDO70007.1 - 1.1e-26 93.3 0.0 1.3e-21 76.8 0.0 2.8 1 1 1 2 2 2 2 SNF2 family N-terminal domain GATase_6 PF13522.6 CDO70007.1 - 6e-12 45.9 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CDO70007.1 - 1.5e-09 37.8 0.0 3.3e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Helicase_C PF00271.31 CDO70007.1 - 1.9e-09 37.9 0.0 6e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pribosyltran PF00156.27 CDO70007.1 - 2.7e-09 36.7 0.1 5.2e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 CDO70007.1 - 0.00027 19.9 0.0 0.00064 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AP_endonuc_2 PF01261.24 CDO70007.1 - 0.14 11.6 0.0 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Septin PF00735.18 CDO70008.1 - 7.2e-116 386.4 0.8 8.8e-116 386.1 0.8 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CDO70008.1 - 1.8e-08 34.5 0.2 7.7e-08 32.4 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CDO70008.1 - 2.9e-06 26.8 0.0 5.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 CDO70008.1 - 3.8e-06 26.9 0.1 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CDO70008.1 - 2.8e-05 23.7 0.7 0.0023 17.5 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CDO70008.1 - 6.8e-05 23.0 0.6 0.11 12.5 0.2 2.4 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 CDO70008.1 - 0.00064 19.0 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 CDO70008.1 - 0.0017 18.7 0.0 0.0036 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CDO70008.1 - 0.0023 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SSE PF00437.20 CDO70008.1 - 0.0034 16.5 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 CDO70008.1 - 0.0047 16.5 0.1 0.097 12.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 CDO70008.1 - 0.0088 16.6 2.0 0.014 15.9 2.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 CDO70008.1 - 0.01 16.1 0.0 0.029 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain IIGP PF05049.13 CDO70008.1 - 0.014 14.5 0.2 0.042 12.9 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.12 CDO70008.1 - 0.021 14.2 0.2 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 CDO70008.1 - 0.039 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CDO70008.1 - 0.048 13.7 0.4 0.56 10.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 CDO70008.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 CDO70008.1 - 0.12 12.4 0.4 0.41 10.7 0.1 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 CDO70008.1 - 0.29 11.6 1.8 0.66 10.4 1.7 1.9 1 1 0 1 1 1 0 AAA domain F-box-like PF12937.7 CDO70009.1 - 0.00068 19.5 1.3 0.00068 19.5 1.3 2.0 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.25 CDO70010.1 - 1.3e-30 106.7 0.0 1.3e-29 103.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70010.1 - 4.9e-05 22.8 0.0 0.15 11.4 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CDO70010.1 - 0.14 12.0 0.8 1.2 9.0 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.32 CDO70011.1 - 6.1e-19 68.0 13.1 0.003 18.3 0.4 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 CDO70011.1 - 3e-16 59.1 1.8 3e-16 59.1 1.8 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 CDO70011.1 - 1.6e-11 43.8 0.6 1.6e-11 43.8 0.6 2.7 3 0 0 3 3 3 1 F-box domain Nup160 PF11715.8 CDO70011.1 - 1.5e-05 23.9 1.6 0.61 8.7 0.0 3.6 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Capsid_VP7 PF17071.5 CDO70012.1 - 0.044 13.1 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Outer capsid protein VP7 SH3_9 PF14604.6 CDO70013.1 - 3.7e-11 42.7 0.0 6.4e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDO70013.1 - 2.8e-06 26.8 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDO70013.1 - 9.3e-05 22.0 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain AAA_5 PF07728.14 CDO70014.1 - 2.5e-07 30.8 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDO70014.1 - 0.00025 21.2 0.0 0.00056 20.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDO70014.1 - 0.0013 19.0 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDO70014.1 - 0.0019 18.6 0.0 0.0092 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 CDO70014.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 CDO70014.1 - 0.064 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 CDO70014.1 - 0.075 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CDO70014.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 CDO70014.1 - 0.11 12.6 0.0 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Aha1_N PF09229.11 CDO70015.1 - 2.3e-22 79.7 0.0 4.7e-22 78.7 0.0 1.5 1 1 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CDO70015.1 - 6.7e-14 52.2 0.0 1.8e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 CDO70015.1 - 0.0022 18.3 6.2 0.0045 17.3 0.3 2.3 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport DUF3429 PF11911.8 CDO70016.1 - 1e-38 132.9 13.7 1.4e-38 132.4 13.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) SKG6 PF08693.10 CDO70017.1 - 0.0075 15.7 0.4 0.022 14.1 0.4 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain HET PF06985.11 CDO70018.1 - 4.4e-08 33.6 1.4 8.5e-05 22.9 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF836 PF05768.14 CDO70019.1 - 9.9e-11 41.9 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) PSP PF04046.16 CDO70019.1 - 9.9e-07 28.5 0.3 2.8e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 PSP Thioredoxin_3 PF13192.6 CDO70019.1 - 0.00065 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain zf-CCHC PF00098.23 CDO70019.1 - 0.0071 16.4 0.5 0.013 15.5 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle NPA PF16469.5 CDO70020.1 - 0.019 15.5 0.1 0.028 15.0 0.1 1.3 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 IF-2B PF01008.17 CDO70021.1 - 8.1e-68 228.7 0.0 9.7e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyt_c_ox_IV PF12270.8 CDO70021.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV G-gamma PF00631.22 CDO70022.1 - 3.9e-14 52.4 0.0 5e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF4200 PF13863.6 CDO70023.1 - 0.076 13.4 0.3 0.076 13.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HSCB_C PF07743.13 CDO70023.1 - 0.9 10.1 7.3 1.2 9.7 2.6 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DDE_3 PF13358.6 CDO70024.1 - 1.2e-11 44.6 0.8 1.5e-11 44.2 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease GST_N_3 PF13417.6 CDO70025.1 - 9.1e-11 42.0 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO70025.1 - 4.9e-08 33.2 0.0 9.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO70025.1 - 2e-07 31.2 0.1 5.3e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO70025.1 - 0.00022 21.2 0.2 0.00045 20.2 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ATP_bind_1 PF03029.17 CDO70026.1 - 1.7e-73 247.4 0.0 2.1e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CDO70026.1 - 0.14 12.3 0.2 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DDE_3 PF13358.6 CDO70027.1 - 3.1e-12 46.5 0.5 3.6e-12 46.3 0.5 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HMG_box_2 PF09011.10 CDO70030.1 - 9.5e-06 26.1 0.6 1.9e-05 25.1 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 CDO70030.1 - 0.00024 21.4 0.8 0.0012 19.2 0.4 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box DUF4255 PF14065.6 CDO70030.1 - 0.022 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) DrsE_2 PF13686.6 CDO70030.1 - 0.031 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family Cas9_PI PF16595.5 CDO70030.1 - 0.033 14.1 0.2 0.033 14.1 0.2 1.5 2 0 0 2 2 2 0 PAM-interacting domain of CRISPR-associated endonuclease Cas9 Arg_decarbox_C PF17944.1 CDO70030.1 - 0.067 13.8 0.7 4 8.1 0.0 2.9 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension DUF2299 PF10061.9 CDO70030.1 - 0.12 12.1 0.2 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) PBP1_TM PF14812.6 CDO70032.1 - 0.0028 18.0 0.3 0.0051 17.1 0.3 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2428 PF10350.9 CDO70032.1 - 0.021 14.1 0.1 0.029 13.6 0.1 1.1 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Velvet PF11754.8 CDO70033.1 - 4.1e-20 72.8 0.0 6.9e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Velvet factor zf-RVT PF13966.6 CDO70034.1 - 0.00018 22.2 0.0 0.00035 21.2 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Retrotran_gag_2 PF14223.6 CDO70035.1 - 2.2e-10 40.3 0.0 1.5e-08 34.4 0.0 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type U79_P34 PF03064.16 CDO70035.1 - 0.03 13.7 1.2 0.053 12.9 1.2 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ribosomal_S25 PF03297.15 CDO70035.1 - 0.18 12.0 1.5 0.44 10.8 1.5 1.6 1 0 0 1 1 1 0 S25 ribosomal protein BUD22 PF09073.10 CDO70036.1 - 2.2e-07 30.6 3.9 3.3e-07 30.0 3.9 1.3 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 CDO70036.1 - 0.00089 18.8 9.5 0.0014 18.2 9.5 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 CDO70036.1 - 0.0056 15.0 6.5 0.0076 14.6 6.5 1.1 1 0 0 1 1 1 1 CDC45-like protein TFIIA PF03153.13 CDO70036.1 - 0.0075 16.3 9.5 0.0075 16.3 9.5 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CNDH2_C PF16858.5 CDO70036.1 - 0.028 14.3 4.2 0.049 13.5 4.2 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term PPP4R2 PF09184.11 CDO70036.1 - 0.1 12.2 12.8 0.21 11.2 12.8 1.5 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 CDO70036.1 - 0.39 8.9 18.8 0.54 8.4 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 CDO70036.1 - 2.1 8.0 17.3 5.5 6.7 17.3 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cauli_VI PF01693.16 CDO70038.1 - 9.3e-11 41.9 0.1 1.7e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin CxC2 PF18803.1 CDO70041.1 - 3.6e-24 85.0 0.1 4.9e-24 84.5 0.1 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 CDO70041.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 CDO70041.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases U79_P34 PF03064.16 CDO70042.1 - 0.003 17.0 14.7 0.0035 16.7 14.7 1.0 1 0 0 1 1 1 1 HSV U79 / HCMV P34 DUF755 PF05501.11 CDO70042.1 - 0.021 15.1 7.7 0.025 14.8 7.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SKA1 PF07160.12 CDO70042.1 - 0.073 12.9 7.3 0.088 12.6 7.3 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 UPF0565 PF10561.9 CDO70042.1 - 0.084 12.1 1.7 0.09 12.0 1.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF3619 PF12279.8 CDO70042.1 - 0.088 13.1 5.2 0.091 13.1 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Vfa1 PF08432.10 CDO70042.1 - 0.45 10.8 15.1 0.51 10.7 15.1 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1664 PF07889.12 CDO70042.1 - 0.61 10.1 5.3 0.67 10.0 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PP31 PF05311.11 CDO70042.1 - 0.92 8.9 10.3 1 8.8 10.3 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) LCD1 PF09798.9 CDO70042.1 - 1.3 7.4 10.5 1.4 7.4 10.5 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein HemX PF04375.14 CDO70042.1 - 1.4 8.1 12.5 1.5 8.1 12.5 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase ALMT PF11744.8 CDO70042.1 - 1.6 7.5 6.2 1.7 7.4 6.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.6 CDO70042.1 - 1.8 7.8 12.5 2.2 7.6 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 CDO70042.1 - 1.9 8.9 13.8 2.2 8.6 13.8 1.1 1 0 0 1 1 1 0 YlqD protein YabA PF06156.13 CDO70042.1 - 1.9 9.2 10.2 2.1 9.0 10.2 1.1 1 0 0 1 1 1 0 Initiation control protein YabA PPL5 PF18168.1 CDO70042.1 - 2.4 7.4 8.7 2.4 7.4 8.7 1.0 1 0 0 1 1 1 0 Prim-pol family 5 CENP-Q PF13094.6 CDO70042.1 - 3.2 7.9 18.9 4.2 7.5 18.9 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Herpes_UL6 PF01763.16 CDO70042.1 - 3.5 6.0 7.1 3.9 5.9 7.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4746 PF15928.5 CDO70042.1 - 3.8 6.9 15.5 4.4 6.6 15.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ATP11 PF06644.11 CDO70042.1 - 4.1 7.1 13.7 4.6 7.0 13.7 1.0 1 0 0 1 1 1 0 ATP11 protein PIEZO PF15917.5 CDO70042.1 - 4.1 6.8 11.2 5 6.5 11.2 1.2 1 0 0 1 1 1 0 Piezo Spore_coat_CotO PF14153.6 CDO70042.1 - 4.1 7.3 18.6 5 7.0 18.6 1.0 1 0 0 1 1 1 0 Spore coat protein CotO XRN_M PF17846.1 CDO70042.1 - 4.2 6.2 7.7 4.7 6.0 7.7 1.0 1 0 0 1 1 1 0 Xrn1 helical domain GrpE PF01025.19 CDO70042.1 - 4.4 6.9 15.5 5.2 6.7 15.5 1.2 1 0 0 1 1 1 0 GrpE TSA PF03249.13 CDO70042.1 - 4.8 5.9 7.5 5.2 5.8 7.5 1.0 1 0 0 1 1 1 0 Type specific antigen EMP24_GP25L PF01105.24 CDO70042.1 - 4.9 7.1 6.5 6.3 6.7 6.5 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD OmpH PF03938.14 CDO70042.1 - 5.1 7.4 21.0 5.7 7.3 21.0 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Folliculin PF11704.8 CDO70042.1 - 6.5 6.6 7.9 7.5 6.4 7.9 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Rrn6 PF10214.9 CDO70042.1 - 6.6 5.1 12.2 7.3 4.9 12.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RNA_pol_Rpc4 PF05132.14 CDO70042.1 - 6.7 7.1 10.8 8 6.9 10.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 NARP1 PF12569.8 CDO70042.1 - 7 5.4 17.1 8.2 5.2 17.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.17 CDO70042.1 - 7.1 6.7 7.1 7.5 6.7 7.1 1.1 1 0 0 1 1 1 0 DDHD domain betaPIX_CC PF16523.5 CDO70042.1 - 7.3 6.5 16.0 7.5 6.5 14.6 1.7 1 1 1 2 2 2 0 betaPIX coiled coil TMEM119 PF15724.5 CDO70042.1 - 7.9 6.5 11.1 8.6 6.3 11.1 1.1 1 0 0 1 1 1 0 TMEM119 family Herpes_UL25 PF01499.16 CDO70042.1 - 8.4 4.8 7.8 9.3 4.6 7.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family EFG_IV PF03764.18 CDO70044.1 - 1.2e-35 122.0 0.1 8.1e-35 119.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 CDO70044.1 - 2.2e-30 104.6 0.0 4.7e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CDO70044.1 - 5e-23 80.9 0.1 1.1e-22 79.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDO70044.1 - 1.2e-12 48.0 0.0 2.7e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 CDO70044.1 - 1.7e-09 37.5 0.0 3.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 CDO70044.1 - 1e-06 28.6 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SBDS_C PF09377.10 CDO70044.1 - 0.0018 18.3 0.0 0.045 13.8 0.0 2.3 2 0 0 2 2 2 1 SBDS protein C-terminal domain SFTA2 PF15210.6 CDO70044.1 - 0.07 13.1 0.0 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Surfactant-associated protein 2 DUF1367 PF07105.11 CDO70044.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) GTP_EFTU PF00009.27 CDO70045.1 - 2.9e-25 89.0 0.1 3.5e-25 88.7 0.1 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain S1-P1_nuclease PF02265.16 CDO70046.1 - 2.7e-45 155.1 0.0 7.6e-43 147.1 0.0 2.7 1 1 0 1 1 1 1 S1/P1 Nuclease WD40 PF00400.32 CDO70048.1 - 3.4e-23 81.5 11.2 4.4e-05 24.2 0.6 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO70048.1 - 7.2e-07 29.4 4.3 0.13 12.6 0.1 4.4 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO70048.1 - 2.5e-05 23.4 0.0 0.41 9.6 0.0 3.6 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3567 PF12091.8 CDO70048.1 - 0.019 15.1 0.0 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) PIF1 PF05970.14 CDO70049.1 - 6.8e-51 173.5 0.2 6.9e-42 143.9 0.0 2.7 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CDO70049.1 - 7.9e-25 87.7 0.0 1.2e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDO70049.1 - 2.1e-12 47.6 0.0 4.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDO70049.1 - 1.1e-06 29.0 0.0 2.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDO70049.1 - 3.1e-05 23.8 0.3 0.0052 16.6 0.2 3.3 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CDO70049.1 - 0.00036 20.9 0.1 0.0013 19.1 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CDO70049.1 - 0.00044 20.3 0.0 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 CDO70049.1 - 0.00071 18.7 0.1 0.0017 17.5 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 CDO70049.1 - 0.00077 19.0 0.1 0.0019 17.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 CDO70049.1 - 0.0017 18.2 0.1 0.28 10.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 CDO70049.1 - 0.0019 18.1 0.3 0.0094 15.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 CDO70049.1 - 0.0029 17.3 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Herpes_Helicase PF02689.14 CDO70049.1 - 0.0051 14.8 0.2 0.1 10.5 0.0 2.4 3 0 0 3 3 3 1 Helicase PhoH PF02562.16 CDO70049.1 - 0.0055 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Mg_chelatase PF01078.21 CDO70049.1 - 0.0068 15.8 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CDO70049.1 - 0.014 15.9 0.0 0.037 14.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter UvrD_C_2 PF13538.6 CDO70049.1 - 0.015 15.1 0.3 0.068 13.0 0.3 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain RsgA_GTPase PF03193.16 CDO70049.1 - 0.022 14.6 0.1 0.052 13.5 0.1 1.6 1 1 0 1 1 1 0 RsgA GTPase Sigma54_activat PF00158.26 CDO70049.1 - 0.024 14.4 0.1 0.052 13.3 0.1 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CDO70049.1 - 0.041 13.6 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CDO70049.1 - 0.046 13.0 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 CDO70049.1 - 0.054 13.9 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 CDO70049.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 CDO70049.1 - 0.064 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 CDO70049.1 - 0.068 13.0 0.2 0.23 11.3 0.2 1.8 1 1 0 1 1 1 0 Helicase AAA_14 PF13173.6 CDO70049.1 - 0.072 13.1 0.0 0.29 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CDO70049.1 - 0.08 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 CDO70049.1 - 0.082 11.9 0.2 0.14 11.1 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 CDO70049.1 - 0.11 12.4 0.0 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CDO70049.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CDO70049.1 - 0.12 12.3 0.0 0.69 9.9 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2157 PF09925.9 CDO70050.1 - 0.077 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) NeA_P2 PF12312.8 CDO70050.1 - 0.15 11.5 0.6 0.27 10.7 0.6 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein zf-NOSIP PF15906.5 CDO70051.1 - 6.9e-12 45.3 0.3 1.3e-11 44.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 CDO70051.1 - 0.00047 20.0 5.0 0.0015 18.3 2.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO70051.1 - 0.00079 19.4 0.7 0.00079 19.4 0.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-TFIIIC PF12660.7 CDO70051.1 - 0.002 18.0 0.3 0.006 16.5 0.2 2.0 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex zf-C3HC4_2 PF13923.6 CDO70051.1 - 0.0074 16.1 2.6 0.0074 16.1 2.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO70051.1 - 0.029 14.2 2.0 0.029 14.2 2.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO70051.1 - 0.062 13.6 1.4 0.062 13.6 1.4 2.2 2 0 0 2 2 2 0 Ring finger domain Bindin PF02084.15 CDO70051.1 - 0.086 13.1 0.5 0.15 12.3 0.5 1.4 1 0 0 1 1 1 0 Bindin zinc-ribbons_6 PF07191.12 CDO70051.1 - 0.091 12.8 2.3 7.7 6.6 1.3 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-C3HC4_4 PF15227.6 CDO70051.1 - 0.59 10.3 5.1 0.16 12.1 1.1 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDO70051.1 - 0.93 9.4 8.7 1.1 9.2 3.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDO70051.1 - 7.4 6.6 7.2 21 5.2 3.7 2.6 2 1 0 2 2 2 0 zinc-RING finger domain DUF302 PF03625.14 CDO70052.1 - 6.3e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF302 Spt5-NGN PF03439.13 CDO70054.1 - 3.1e-22 78.3 0.0 7.1e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CDO70054.1 - 2.7e-19 68.4 35.2 1.2e-07 31.4 0.2 8.6 9 0 0 9 9 9 6 KOW motif Spt5_N PF11942.8 CDO70054.1 - 2.3e-17 63.8 15.1 2.3e-17 63.8 15.1 3.3 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 CDO70054.1 - 2.6e-05 24.7 33.1 0.00062 20.3 32.9 2.7 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 UvdE PF03851.14 CDO70055.1 - 9.7e-89 297.3 0.0 1.3e-88 296.9 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF543 PF04418.12 CDO70056.1 - 5.1e-29 100.1 0.2 5.8e-29 99.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Ndc1_Nup PF09531.10 CDO70056.1 - 0.25 10.0 0.0 0.25 10.0 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HET PF06985.11 CDO70057.1 - 0.00014 22.2 0.1 0.00027 21.3 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UL45 PF05473.12 CDO70057.1 - 0.21 11.2 0.3 0.4 10.3 0.3 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like RVT_1 PF00078.27 CDO70062.1 - 2.9e-15 56.4 0.0 4.3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO70062.1 - 5.3e-07 29.9 0.0 1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO70062.1 - 0.001 19.7 0.0 0.0022 18.6 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Velvet PF11754.8 CDO70068.1 - 2e-31 109.9 0.8 4.7e-31 108.6 0.8 1.6 1 1 0 1 1 1 1 Velvet factor MoCF_biosynth PF00994.24 CDO70069.1 - 3.6e-29 101.3 0.0 5.5e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 CDO70069.1 - 0.025 14.7 0.0 0.09 12.9 0.0 1.9 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain GPI-anchored PF10342.9 CDO70070.1 - 1.9e-11 44.5 1.1 1.9e-11 44.5 1.1 1.9 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pkinase PF00069.25 CDO70071.1 - 5.4e-06 26.0 0.0 2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain SYF2 PF08231.12 CDO70072.1 - 6.1e-62 208.7 10.8 6.1e-62 208.7 10.8 2.2 2 0 0 2 2 2 1 SYF2 splicing factor SAE2 PF08573.10 CDO70073.1 - 1.3e-20 74.6 3.2 1.3e-20 74.6 3.2 3.7 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus HR1 PF02185.16 CDO70073.1 - 2.3 8.4 7.9 3.2 7.9 3.2 2.9 1 1 1 2 2 2 0 Hr1 repeat BicD PF09730.9 CDO70073.1 - 3.3 6.0 18.9 1.1 7.6 5.3 2.2 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D FUSC PF04632.12 CDO70073.1 - 4.7 5.6 8.2 7.8 4.9 8.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2680 PF10925.8 CDO70073.1 - 6.5 6.8 10.3 16 5.6 0.5 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2680) PRKG1_interact PF15898.5 CDO70073.1 - 8.2 7.4 20.5 14 6.6 3.0 4.2 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain AAA_23 PF13476.6 CDO70076.1 - 0.0039 17.7 2.8 0.0039 17.7 2.8 1.6 2 0 0 2 2 2 1 AAA domain DUF1840 PF08895.11 CDO70076.1 - 0.082 13.2 0.0 0.082 13.2 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) DUF641 PF04859.12 CDO70076.1 - 1.1 9.6 10.6 1.8 8.9 9.2 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 CDO70076.1 - 1.2 8.4 10.2 2.7 7.3 10.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 CDO70076.1 - 1.5 7.3 5.6 2.2 6.8 5.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mst1_SARAH PF11629.8 CDO70076.1 - 1.7 8.8 6.7 8.1 6.6 3.5 2.7 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 HSCB_C PF07743.13 CDO70076.1 - 1.9 9.0 8.2 0.46 11.0 4.5 1.9 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain IFT46_B_C PF12317.8 CDO70076.1 - 2.3 7.9 4.9 1.6 8.4 0.0 2.5 2 1 1 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal GrpE PF01025.19 CDO70076.1 - 2.8 7.6 12.8 0.6 9.8 7.0 2.4 3 0 0 3 3 3 0 GrpE Prefoldin PF02996.17 CDO70076.1 - 3 7.8 8.2 0.36 10.7 3.9 1.6 2 0 0 2 2 2 0 Prefoldin subunit PRP1_N PF06424.12 CDO70076.1 - 3.8 7.9 8.4 3.3 8.1 4.3 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Fib_alpha PF08702.10 CDO70076.1 - 5.4 7.2 8.6 15 5.8 8.6 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CCDC-167 PF15188.6 CDO70076.1 - 7.3 7.0 9.6 1.7 9.1 5.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 GCN5L1 PF06320.13 CDO70076.1 - 7.9 6.7 17.9 0.048 13.8 3.5 2.8 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) DnaJ PF00226.31 CDO70078.1 - 2.7e-19 69.1 0.1 8.3e-19 67.5 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain Tho2 PF11262.8 CDO70078.1 - 0.094 11.9 4.6 0.15 11.2 4.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 RRM_1 PF00076.22 CDO70078.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Synaptobrevin PF00957.21 CDO70079.1 - 1.6e-34 117.6 4.4 1.8e-34 117.4 4.4 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.6 CDO70079.1 - 0.036 13.0 0.5 0.042 12.8 0.5 1.0 1 0 0 1 1 1 0 TMEM117 protein family Shisa PF13908.6 CDO70079.1 - 0.067 13.4 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF515 PF04415.12 CDO70079.1 - 1.7 7.0 6.9 1.8 6.8 6.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF515) Pkinase PF00069.25 CDO70081.1 - 2.4e-73 246.8 0.0 3.3e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70081.1 - 1.7e-41 142.2 0.0 2.4e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO70081.1 - 1.2e-11 44.5 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDO70081.1 - 0.00086 18.7 0.2 0.0018 17.7 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDO70081.1 - 0.024 13.6 0.1 0.046 12.6 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Ntox14 PF15522.6 CDO70081.1 - 0.052 13.0 0.3 0.1 12.0 0.3 1.4 1 0 0 1 1 1 0 Novel toxin 14 WBP-1 PF11669.8 CDO70081.1 - 0.21 12.3 0.7 0.89 10.2 0.7 2.1 1 0 0 1 1 1 0 WW domain-binding protein 1 APH PF01636.23 CDO70081.1 - 8.6 6.2 8.0 0.71 9.7 0.1 2.8 3 1 1 4 4 4 0 Phosphotransferase enzyme family GLE1 PF07817.13 CDO70082.1 - 8.9e-51 172.5 0.0 1.7e-50 171.6 0.0 1.5 1 0 0 1 1 1 1 GLE1-like protein Staygreen PF12638.7 CDO70082.1 - 0.021 14.6 2.1 0.53 10.1 0.8 2.4 1 1 1 2 2 2 0 Staygreen protein HTH_3 PF01381.22 CDO70084.1 - 1.6e-07 31.2 0.0 1.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CDO70084.1 - 5.2e-07 29.9 0.0 6.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CDO70084.1 - 0.00069 19.6 0.0 0.00091 19.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CDO70084.1 - 0.0047 16.7 0.1 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 CDO70084.1 - 0.093 12.4 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 Ribosomal_S11 PF00411.19 CDO70085.1 - 6.7e-47 158.5 1.5 8.4e-47 158.1 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 CDO70085.1 - 0.096 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Acyltransferase PF01553.21 CDO70086.1 - 4.4e-05 23.1 0.0 7.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF4904 PF16247.5 CDO70087.1 - 0.16 11.7 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) ERM PF00769.19 CDO70088.1 - 0.0089 15.9 2.8 0.015 15.1 2.8 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Spc42p PF11544.8 CDO70088.1 - 0.12 12.4 0.5 0.6 10.1 0.1 2.1 2 0 0 2 2 2 0 Spindle pole body component Spc42p DivIC PF04977.15 CDO70088.1 - 0.37 10.6 3.2 3 7.7 0.7 2.5 2 0 0 2 2 2 0 Septum formation initiator Synaptobrevin PF00957.21 CDO70089.1 - 3.9e-27 93.9 0.4 5.5e-27 93.4 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CDO70089.1 - 6.7e-23 80.5 0.0 1e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain ClpB_D2-small PF10431.9 CDO70089.1 - 0.13 12.3 0.3 0.27 11.3 0.3 1.4 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein Cep57_CLD PF14073.6 CDO70090.1 - 0.023 14.7 10.3 0.18 11.8 9.9 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 GAS PF13851.6 CDO70090.1 - 0.051 12.9 14.0 0.017 14.5 11.3 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding OmpH PF03938.14 CDO70090.1 - 0.27 11.6 9.6 0.6 10.5 9.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Prefoldin_3 PF13758.6 CDO70090.1 - 0.42 10.7 4.8 1.3 9.2 0.4 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF4407 PF14362.6 CDO70090.1 - 3.9 6.7 10.1 9.7 5.4 10.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 CDO70090.1 - 6.1 7.6 8.9 34 5.2 2.1 3.2 2 1 1 3 3 3 0 Occludin homology domain Mo25 PF08569.11 CDO70091.1 - 7.2e-130 433.1 5.3 3e-128 427.8 1.9 2.0 2 0 0 2 2 2 2 Mo25-like Glycos_transf_2 PF00535.26 CDO70093.1 - 1.2e-30 106.6 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CDO70093.1 - 3.2e-10 40.3 0.0 4.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CDO70093.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CDO70093.1 - 0.018 14.5 0.0 0.047 13.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 F-box-like PF12937.7 CDO70094.1 - 2.2e-05 24.3 0.1 0.00016 21.5 0.0 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 CDO70094.1 - 0.2 11.6 1.4 11 6.0 0.1 3.2 3 0 0 3 3 3 0 F-box domain Lactonase PF10282.9 CDO70095.1 - 3e-12 46.5 0.0 5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Lactonase PF10282.9 CDO70096.1 - 1.3e-33 116.7 0.0 9.7e-22 77.7 0.0 2.0 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Ribosomal_L24e PF01246.20 CDO70097.1 - 3.8e-30 103.9 0.4 3.8e-30 103.9 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e DUF680 PF05079.12 CDO70097.1 - 0.41 11.4 2.2 0.97 10.2 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF680) Ribosomal_60s PF00428.19 CDO70097.1 - 5.3 7.7 12.9 7.9 7.1 12.9 1.4 1 1 0 1 1 1 0 60s Acidic ribosomal protein MAP65_ASE1 PF03999.12 CDO70098.1 - 1e-68 232.6 0.4 1.5e-61 208.9 0.0 2.6 2 1 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Exonuc_VII_L PF02601.15 CDO70098.1 - 0.13 11.9 5.0 0.3 10.6 0.2 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 CDO70098.1 - 1.1 9.2 5.1 2.3 8.2 0.9 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 CDO70098.1 - 5 6.9 12.3 0.26 11.1 0.6 3.4 2 2 2 4 4 4 0 Apolipoprotein A1/A4/E domain Acetyltransf_1 PF00583.25 CDO70099.1 - 1e-11 45.1 0.0 1.3e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO70099.1 - 7.7e-09 35.9 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDO70099.1 - 8.1e-09 35.5 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDO70099.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein adh_short_C2 PF13561.6 CDO70100.1 - 3.6e-55 187.1 0.3 4.3e-55 186.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO70100.1 - 4.2e-47 160.1 0.3 5.3e-47 159.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO70100.1 - 4.1e-13 49.6 0.2 7.6e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO70100.1 - 0.0021 17.6 0.1 0.0072 15.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 CDO70100.1 - 0.12 12.5 0.1 0.33 11.0 0.1 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DUF1744 PF08490.12 CDO70101.1 - 7.7e-136 452.8 0.0 1.4e-135 452.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CDO70101.1 - 1.3e-77 261.3 0.0 2.2e-77 260.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CDO70101.1 - 2.7e-11 42.9 0.3 8.9e-09 34.6 0.1 3.9 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CDO70101.1 - 1.9e-07 31.0 0.2 5.7e-07 29.4 0.2 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CDO70101.1 - 0.0031 17.5 0.0 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily TF_Zn_Ribbon PF08271.12 CDO70101.1 - 0.025 14.1 0.3 0.084 12.4 0.1 2.1 2 1 0 2 2 2 0 TFIIB zinc-binding zf-C4pol PF14260.6 CDO70101.1 - 0.24 11.9 2.0 0.77 10.3 2.0 1.9 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta FoP_duplication PF13865.6 CDO70101.1 - 1.8 9.1 8.5 4.4 7.9 8.5 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PHD PF00628.29 CDO70102.1 - 5.9e-07 29.3 1.0 5.9e-07 29.3 1.0 3.9 4 0 0 4 4 4 1 PHD-finger Hydantoinase_B PF02538.14 CDO70103.1 - 1.9e-211 703.0 0.1 2.1e-211 702.8 0.1 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Tetraspanin PF00335.20 CDO70105.1 - 9.1e-12 45.2 0.2 1e-11 45.0 0.2 1.1 1 0 0 1 1 1 1 Tetraspanin family ABC2_membrane_3 PF12698.7 CDO70105.1 - 0.00076 18.7 8.3 0.0011 18.2 8.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4064 PF13273.6 CDO70105.1 - 0.0094 16.2 10.0 0.023 15.0 8.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF4064) TssN PF17555.2 CDO70105.1 - 0.021 14.2 0.5 0.039 13.3 0.5 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN 7TM_GPCR_Srh PF10318.9 CDO70105.1 - 0.027 13.5 2.8 0.035 13.2 2.8 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF1129 PF06570.11 CDO70105.1 - 0.032 13.7 0.5 0.043 13.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Cellulose_synt PF03552.14 CDO70105.1 - 0.053 12.0 0.7 0.065 11.7 0.7 1.1 1 0 0 1 1 1 0 Cellulose synthase TctB PF07331.11 CDO70105.1 - 0.071 13.4 5.1 0.14 12.4 5.1 1.5 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family TMEM43 PF07787.12 CDO70105.1 - 0.096 12.1 7.4 0.25 10.7 0.5 2.2 2 0 0 2 2 2 0 Transmembrane protein 43 TatC PF00902.18 CDO70105.1 - 0.11 12.4 7.0 0.21 11.4 7.0 1.4 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF1146 PF06612.11 CDO70105.1 - 0.4 10.8 12.7 0.061 13.4 7.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1146) DUF2207 PF09972.9 CDO70105.1 - 2 7.1 5.0 0.55 8.9 2.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.6 CDO70105.1 - 3 7.6 7.8 6.8 6.4 7.3 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2721 PF11026.8 CDO70105.1 - 5.8 6.8 11.2 29 4.6 11.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) Herpes_US9 PF06072.11 CDO70105.1 - 9.5 6.2 8.2 0.96 9.4 0.6 2.7 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 SUR7 PF06687.12 CDO70105.1 - 9.7 5.8 15.3 2.2 7.8 5.4 2.2 1 1 1 2 2 2 0 SUR7/PalI family Glyco_hydro_12 PF01670.16 CDO70106.1 - 2.4e-36 125.7 9.4 2.8e-36 125.5 9.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Hydrophobin PF01185.18 CDO70107.1 - 5.2e-23 81.5 11.1 6.1e-23 81.3 11.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 CDO70108.1 - 1e-22 80.5 7.2 1.3e-22 80.2 7.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 CDO70109.1 - 5.5e-24 84.6 9.5 6.6e-24 84.3 9.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 CDO70110.1 - 1.5e-24 86.4 12.4 1.9e-24 86.1 12.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Lamprin PF06403.11 CDO70110.1 - 0.5 10.3 4.4 2.2 8.3 4.4 1.9 1 1 0 1 1 1 0 Lamprin Toxin_12 PF07740.12 CDO70110.1 - 6.8 7.5 9.1 7.5 7.3 0.6 2.4 2 0 0 2 2 2 0 Ion channel inhibitory toxin Hydrophobin PF01185.18 CDO70111.1 - 3.2e-24 85.4 8.9 3.8e-24 85.1 8.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 CDO70112.1 - 3e-24 85.5 11.8 3.6e-24 85.2 11.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 CDO70113.1 - 2.2e-17 63.4 2.0 2.8e-17 63.1 2.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin SOG2 PF10428.9 CDO70114.1 - 0.092 11.9 20.5 0.1 11.8 20.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Smg8_Smg9 PF10220.9 CDO70114.1 - 2.7 6.2 9.2 3.3 5.9 9.2 1.0 1 0 0 1 1 1 0 Smg8_Smg9 DUF572 PF04502.13 CDO70114.1 - 8 6.0 7.8 9.7 5.7 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RRM_1 PF00076.22 CDO70119.1 - 0.016 15.0 0.0 0.071 12.9 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_assoc3 PF16637.5 CDO70120.1 - 0.035 14.3 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz Shisa PF13908.6 CDO70120.1 - 0.075 13.3 1.1 0.12 12.7 0.1 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Peptidase_M28 PF04389.17 CDO70121.1 - 7.2e-18 65.0 0.0 1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CDO70121.1 - 0.0039 16.9 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Asp PF00026.23 CDO70123.1 - 1.9e-15 57.1 0.4 7e-15 55.2 0.4 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 CDO70123.1 - 0.04 13.7 0.2 0.17 11.7 0.2 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal FAD_binding_3 PF01494.19 CDO70124.1 - 4.1e-16 59.2 0.3 4.3e-15 55.8 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Proteasom_PSMB PF10508.9 CDO70126.1 - 0.084 11.4 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit DUF2353 PF09789.9 CDO70126.1 - 0.086 12.2 0.5 0.13 11.6 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) SRF-TF PF00319.18 CDO70127.1 - 2.4e-13 49.3 0.0 4.6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) His_Phos_2 PF00328.22 CDO70128.1 - 6.3e-27 94.9 0.0 8.9e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) VPS28 PF03997.12 CDO70129.1 - 8.7e-73 244.0 0.0 1e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein DUF4451 PF14616.6 CDO70133.1 - 3.2e-06 27.4 6.7 0.033 14.4 0.3 4.0 3 1 1 4 4 4 3 Domain of unknown function (DUF4451) Tmemb_55A PF09788.9 CDO70133.1 - 0.016 14.3 5.3 3.8 6.5 0.3 3.5 3 1 0 3 3 3 0 Transmembrane protein 55A S8_pro-domain PF16470.5 CDO70133.1 - 0.047 14.5 0.0 18 6.2 0.0 3.1 3 0 0 3 3 3 0 Peptidase S8 pro-domain Zn_ribbon_recom PF13408.6 CDO70133.1 - 0.077 13.5 0.8 11 6.6 0.0 2.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Prim_Zn_Ribbon PF08273.12 CDO70133.1 - 0.17 12.2 1.2 9.6 6.6 0.1 3.1 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase PHD PF00628.29 CDO70133.1 - 0.29 11.0 6.8 17 5.4 0.4 4.2 4 0 0 4 4 4 0 PHD-finger Pkinase PF00069.25 CDO70134.1 - 2e-60 204.4 0.0 2.3e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70134.1 - 5.1e-18 65.3 0.0 6.9e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO70134.1 - 7.3e-10 39.2 0.1 4.5e-06 26.8 0.0 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 CDO70134.1 - 9.7e-05 22.0 0.1 0.0002 21.0 0.1 1.5 1 1 0 1 1 1 1 RIO1 family DUF1679 PF07914.11 CDO70134.1 - 0.0034 16.3 0.1 1.2 8.0 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 CDO70134.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CDO70134.1 - 0.021 13.6 0.0 0.073 11.8 0.0 1.7 1 1 0 2 2 2 0 Fungal protein kinase Fungal_trans PF04082.18 CDO70135.1 - 0.0015 17.6 0.1 0.45 9.5 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fungal_trans PF04082.18 CDO70136.1 - 8.7e-22 77.4 2.3 1.9e-21 76.3 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain DLIC PF05783.11 CDO70136.1 - 6 5.6 6.0 10 4.8 6.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) NUDE_C PF04880.13 CDO70136.1 - 6.8 7.1 8.1 15 6.0 8.1 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region SQS_PSY PF00494.19 CDO70138.1 - 2.8e-27 95.9 0.2 5.3e-27 95.0 0.2 1.5 1 1 0 1 1 1 1 Squalene/phytoene synthase RCC1 PF00415.18 CDO70139.1 - 1.6e-45 153.5 12.2 6e-12 46.0 0.0 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDO70139.1 - 1.4e-23 82.1 16.4 2.5e-09 36.7 0.4 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Reg_prop PF07494.11 CDO70139.1 - 0.19 12.1 0.5 88 3.9 0.0 4.0 4 0 0 4 4 4 0 Two component regulator propeller FAT PF02259.23 CDO70140.1 - 6.1e-120 400.6 5.8 6.1e-120 400.6 5.8 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 CDO70140.1 - 5.2e-67 226.3 0.1 1.5e-66 224.8 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CDO70140.1 - 1.1e-58 197.7 12.7 5.4e-56 189.0 2.1 5.7 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CDO70140.1 - 1.2e-40 137.9 0.1 1.2e-40 137.9 0.1 4.0 4 0 0 4 4 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 CDO70140.1 - 2e-16 60.1 15.0 0.003 17.9 0.1 10.7 7 2 4 11 11 11 3 HEAT repeats FATC PF02260.20 CDO70140.1 - 8.4e-16 57.5 0.8 2.6e-15 55.9 0.8 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CDO70140.1 - 6.7e-11 41.5 23.8 0.046 14.0 0.1 11.2 12 0 0 12 12 11 3 HEAT repeat Cnd1 PF12717.7 CDO70140.1 - 9.7e-06 25.7 7.7 0.13 12.3 0.1 6.1 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 CDO70140.1 - 1.4e-05 25.5 0.4 0.13 12.8 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat HEAT_EZ PF13513.6 CDO70140.1 - 1.7e-05 25.2 27.5 0.002 18.6 0.2 11.5 14 2 2 16 16 12 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CDO70140.1 - 2.3e-05 24.9 3.3 16 6.2 0.1 8.2 8 2 2 10 10 10 0 Vacuolar 14 Fab1-binding region TPR_7 PF13176.6 CDO70140.1 - 9.1e-05 22.2 3.1 0.03 14.3 0.2 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat CLASP_N PF12348.8 CDO70140.1 - 0.00054 19.6 3.5 6.5 6.2 0.1 5.6 5 1 1 6 6 6 2 CLASP N terminal IFRD PF05004.13 CDO70140.1 - 0.00067 18.9 5.1 0.32 10.0 0.5 5.9 4 1 2 6 6 6 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 CDO70140.1 - 0.0032 17.6 6.4 7.6 6.8 0.1 6.7 7 2 0 7 7 6 1 Required for nuclear transport of RNA pol II C-terminus 1 TPR_1 PF00515.28 CDO70140.1 - 0.043 13.7 0.6 13 5.8 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Cohesin_HEAT PF12765.7 CDO70140.1 - 0.14 12.4 9.7 0.18 12.2 0.2 4.7 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion TPR_2 PF07719.17 CDO70140.1 - 0.18 12.0 8.5 2.9 8.2 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4042 PF13251.6 CDO70140.1 - 0.76 9.5 7.5 17 5.1 1.5 4.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4042) ParcG PF10274.9 CDO70140.1 - 3.1 7.9 9.7 3.5 7.7 0.1 4.6 3 1 1 4 4 4 0 Parkin co-regulated protein RCC1 PF00415.18 CDO70141.1 - 1.2e-16 61.0 1.0 0.0001 22.9 0.0 5.3 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDO70141.1 - 6.2e-08 32.2 14.9 0.00038 20.2 0.3 5.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 CDO70141.1 - 0.0097 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like Alpha_kinase PF02816.18 CDO70145.1 - 6.2e-07 29.7 0.0 3.6e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Alpha-kinase family T4SS_TraI PF16932.5 CDO70145.1 - 0.047 12.8 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer GREB1 PF15782.5 CDO70145.1 - 2.8 4.9 6.6 3.8 4.5 6.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3818 PF12825.7 CDO70146.1 - 0.18 10.8 2.6 0.35 9.8 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Pkinase_fungal PF17667.1 CDO70148.1 - 3.4e-50 171.0 0.0 1.4e-49 169.0 0.0 1.9 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO70148.1 - 0.0052 16.7 0.1 3.9 7.3 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family HpcH_HpaI PF03328.14 CDO70149.1 - 9.4e-21 74.0 0.0 9.7e-20 70.6 0.0 1.9 1 1 1 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family DUF751 PF05421.11 CDO70150.1 - 0.15 12.8 3.3 2.3 9.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF751) Inositol_P PF00459.25 CDO70151.1 - 4e-49 167.6 0.0 2.4e-48 165.0 0.0 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family MMR_HSR1 PF01926.23 CDO70153.1 - 5.4e-18 65.1 0.1 1e-14 54.5 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CDO70153.1 - 4.7e-08 32.7 0.0 2.1e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDO70153.1 - 7.1e-08 32.5 0.0 2.4e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CDO70153.1 - 0.0003 20.4 0.0 0.024 14.2 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CDO70153.1 - 0.00053 20.1 0.0 0.03 14.4 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 CDO70153.1 - 0.0038 17.6 0.1 0.36 11.2 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 CDO70153.1 - 0.014 14.7 0.0 0.055 12.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 CDO70153.1 - 0.028 14.6 0.0 4.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CDO70153.1 - 0.04 13.5 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CDO70153.1 - 0.044 12.8 0.0 0.11 11.4 0.0 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Septin PF00735.18 CDO70153.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_18 PF13238.6 CDO70153.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.2 3 0 0 3 3 3 0 AAA domain Glyco_trans_2_3 PF13632.6 CDO70154.1 - 3.3e-59 200.1 0.4 3.3e-59 200.1 0.4 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CDO70154.1 - 3.9e-05 23.7 0.0 8.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CDO70154.1 - 0.0016 18.2 0.0 0.0064 16.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CDO70154.1 - 0.013 14.9 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 CDO70155.1 - 1.2e-18 67.2 0.1 4.5e-18 65.3 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 YniB PF14002.6 CDO70155.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 YniB-like protein Glyco_trans_2_3 PF13632.6 CDO70156.1 - 9.5e-60 201.9 0.6 3.2e-59 200.1 0.6 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CDO70156.1 - 2.2e-06 27.7 0.0 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CDO70156.1 - 0.0011 18.9 0.0 0.0036 17.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CDO70156.1 - 0.011 15.3 0.0 0.099 12.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 CDO70157.1 - 5.1e-18 65.2 0.0 9.6e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 CDO70158.1 - 4e-16 59.0 0.3 1.6e-15 57.1 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 CDO70159.1 - 7.3e-53 179.4 1.0 7.3e-53 179.4 1.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CDO70159.1 - 5.5e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CDO70159.1 - 0.013 15.3 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CDO70159.1 - 0.033 13.7 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 FHA PF00498.26 CDO70160.1 - 0.00056 20.2 0.0 0.0018 18.6 0.0 2.0 2 0 0 2 2 2 1 FHA domain MscS_porin PF12795.7 CDO70160.1 - 0.015 14.9 2.3 0.022 14.3 2.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Borrelia_REV PF03978.13 CDO70160.1 - 0.07 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Macoilin PF09726.9 CDO70160.1 - 0.075 11.6 0.0 0.085 11.4 0.0 1.1 1 0 0 1 1 1 0 Macoilin family ATP_bind_1 PF03029.17 CDO70161.1 - 7.4e-74 248.6 0.0 1.1e-73 248.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CDO70161.1 - 2.7e-05 23.8 0.0 0.00036 20.1 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CDO70161.1 - 8.6e-05 22.4 2.0 0.0016 18.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 CDO70161.1 - 0.00018 20.6 0.0 0.075 12.0 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CDO70161.1 - 0.00026 21.1 0.0 0.0037 17.3 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CDO70161.1 - 0.0028 16.9 0.3 0.11 11.6 0.0 2.5 3 0 0 3 3 3 1 G-protein alpha subunit RsgA_GTPase PF03193.16 CDO70161.1 - 0.0032 17.4 0.2 0.88 9.5 0.1 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_33 PF13671.6 CDO70161.1 - 0.004 17.3 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CDO70161.1 - 0.0055 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.18 CDO70161.1 - 0.0066 16.0 0.1 0.035 13.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 CDO70161.1 - 0.0095 16.5 0.0 0.096 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CDO70161.1 - 0.034 13.3 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 CDO70161.1 - 0.053 13.2 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDO70161.1 - 0.055 12.8 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 CDO70161.1 - 0.056 13.3 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_PrkA PF08298.11 CDO70161.1 - 0.061 12.2 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_16 PF13191.6 CDO70161.1 - 0.067 13.6 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain GrpE PF01025.19 CDO70161.1 - 0.068 12.8 1.6 1.5 8.5 0.0 2.3 1 1 1 2 2 2 0 GrpE DUF87 PF01935.17 CDO70161.1 - 0.07 13.2 0.1 6.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain TsaE PF02367.17 CDO70161.1 - 0.072 13.1 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 CDO70161.1 - 0.095 11.9 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Arf PF00025.21 CDO70161.1 - 0.16 11.4 0.0 1.2 8.5 0.0 2.3 3 0 0 3 3 3 0 ADP-ribosylation factor family SRP54 PF00448.22 CDO70161.1 - 0.16 11.6 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 CDO70161.1 - 0.16 11.5 0.2 1.2 8.7 0.2 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.25 CDO70162.1 - 6.3e-72 242.1 0.0 7.3e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70162.1 - 1.9e-32 112.6 0.0 2.6e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO70162.1 - 0.00019 21.4 0.3 0.0044 17.0 0.2 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO70162.1 - 0.00038 19.5 0.3 0.0043 16.0 0.3 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDO70162.1 - 0.019 14.3 0.0 0.096 12.0 0.0 2.0 1 1 1 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 CDO70162.1 - 0.027 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 CDO70162.1 - 0.082 12.3 0.6 0.22 10.8 0.6 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDO70162.1 - 0.082 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 RIO1 family WSC PF01822.19 CDO70163.1 - 6e-69 228.3 51.9 7.1e-20 71.0 9.9 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 CDO70163.1 - 2.2e-28 99.1 0.0 5.3e-27 94.5 0.0 2.7 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CDO70163.1 - 7.7e-15 55.0 2.3 2.4e-14 53.4 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1929) DUF5122 PF17164.4 CDO70163.1 - 0.02 15.2 0.9 6.4 7.2 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Kelch_2 PF07646.15 CDO70163.1 - 0.046 13.7 1.1 3.7 7.7 0.0 4.1 5 0 0 5 5 5 0 Kelch motif SAC3_GANP PF03399.16 CDO70164.1 - 5.3e-67 226.3 3.9 8e-67 225.7 3.9 1.2 1 0 0 1 1 1 1 SAC3/GANP family Fer4_17 PF13534.6 CDO70164.1 - 0.066 13.8 0.3 0.24 12.0 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF2347 PF09804.9 CDO70165.1 - 5.7e-44 150.8 0.0 9.6e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 CDO70165.1 - 0.00012 20.9 0.0 0.94 8.1 0.1 3.1 2 1 0 2 2 2 2 Transport protein Avl9 SPA PF08616.10 CDO70165.1 - 0.052 13.5 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Stabilization of polarity axis SMYLE_N PF18615.1 CDO70167.1 - 6.5 6.2 7.3 17 4.9 7.3 1.6 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Gti1_Pac2 PF09729.9 CDO70168.1 - 1.1e-55 188.5 0.5 5.3e-55 186.3 0.0 2.2 2 1 0 2 2 2 1 Gti1/Pac2 family LAL_C2 PF18603.1 CDO70168.1 - 0.047 13.9 0.1 0.099 12.8 0.1 1.5 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 Transposase_21 PF02992.14 CDO70170.1 - 2.6e-10 39.9 0.0 5.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 TSC22 PF01166.18 CDO70172.1 - 0.029 14.7 0.0 0.093 13.1 0.0 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family HsbA PF12296.8 CDO70173.1 - 0.027 14.9 0.6 0.088 13.2 0.3 2.1 1 1 0 1 1 1 0 Hydrophobic surface binding protein A zf-RING_2 PF13639.6 CDO70174.1 - 2.7e-07 30.8 7.4 5.6e-07 29.8 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 CDO70174.1 - 1.5e-05 25.1 4.3 3.4e-05 23.9 4.3 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CDO70174.1 - 0.00044 20.2 1.9 0.0011 18.9 1.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CDO70174.1 - 0.0035 17.6 6.7 0.0035 17.6 6.7 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain RINGv PF12906.7 CDO70174.1 - 0.019 15.1 6.0 0.038 14.1 6.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CDO70174.1 - 0.055 13.8 7.4 0.13 12.5 7.4 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 CDO70174.1 - 0.06 13.2 8.0 0.11 12.4 8.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDO70174.1 - 0.1 12.4 7.2 0.25 11.2 7.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CDO70174.1 - 0.34 10.7 5.5 0.64 9.9 5.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 CDO70174.1 - 0.43 10.2 9.7 0.033 13.8 4.4 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 CDO70174.1 - 0.79 9.7 4.7 0.36 10.8 1.9 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_11 PF17123.5 CDO70174.1 - 1.7 8.4 3.8 6.4 6.6 1.0 2.5 2 0 0 2 2 2 0 RING-like zinc finger Cnd1 PF12717.7 CDO70174.1 - 2.1 8.4 6.8 5.8 6.9 0.1 3.7 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Prok-RING_4 PF14447.6 CDO70174.1 - 2.4 8.1 4.9 5.4 6.9 4.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 CDO70174.1 - 4.6 7.2 6.4 8.7 6.3 6.4 1.5 1 0 0 1 1 1 0 PHD-finger p450 PF00067.22 CDO70175.1 - 2.4e-74 250.8 0.0 5.4e-74 249.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 HSP20 PF00011.21 CDO70176.1 - 1.4e-10 41.2 0.0 4.7e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Presenilin PF01080.17 CDO70176.1 - 1.3 7.7 9.1 1.7 7.4 9.1 1.1 1 0 0 1 1 1 0 Presenilin SMN PF06003.12 CDO70176.1 - 1.8 7.8 4.8 2.6 7.2 4.8 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Peptidase_S46 PF10459.9 CDO70176.1 - 2 7.0 5.6 2.5 6.6 5.6 1.0 1 0 0 1 1 1 0 Peptidase S46 SLC12 PF03522.15 CDO70176.1 - 4.6 6.2 8.3 7.1 5.5 8.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 CDO70176.1 - 5.6 5.1 30.3 6.9 4.8 30.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2046 PF09755.9 CDO70177.1 - 9.7e-13 48.0 10.4 1.8e-12 47.1 8.3 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) ChAPs PF09295.10 CDO70179.1 - 1.1e-149 498.8 0.0 1.3e-148 495.3 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 CDO70179.1 - 1.9e-08 34.7 2.3 5.6e-05 23.6 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDO70179.1 - 5.8e-06 26.0 7.8 2.4 8.5 0.1 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDO70179.1 - 0.0001 22.3 1.1 0.95 9.8 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDO70179.1 - 0.0012 19.3 1.1 18 6.2 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDO70179.1 - 0.0046 16.2 3.4 0.73 9.0 0.2 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO70179.1 - 0.0069 16.6 8.3 0.19 12.0 2.0 4.2 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CDO70179.1 - 0.046 14.4 0.6 0.79 10.4 0.1 3.3 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDO70179.1 - 0.057 13.3 4.3 29 4.7 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 CDO70179.1 - 2.1 7.2 11.8 0.19 10.6 0.1 2.9 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 AA_kinase PF00696.28 CDO70180.1 - 1.1e-32 113.5 0.0 5e-32 111.4 0.0 2.1 2 1 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 CDO70180.1 - 7e-11 41.7 0.3 0.00015 21.5 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 CDO70180.1 - 1.8e-07 30.9 0.8 0.00016 21.4 0.1 2.6 2 0 0 2 2 2 2 ACT domain Rrf2 PF02082.20 CDO70180.1 - 0.15 12.4 0.1 2.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator G-alpha PF00503.20 CDO70181.1 - 4.4e-105 351.7 0.0 9.5e-69 232.2 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit TniB PF05621.11 CDO70181.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 CDO70181.1 - 0.012 15.3 0.0 0.032 14.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arf PF00025.21 CDO70181.1 - 0.016 14.7 0.1 0.55 9.7 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DAP3 PF10236.9 CDO70181.1 - 0.016 14.4 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CDO70181.1 - 0.022 15.2 0.1 0.049 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 CDO70181.1 - 0.046 13.0 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 CDO70181.1 - 0.13 12.0 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CDO70181.1 - 0.17 12.4 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter HMG-CoA_red PF00368.18 CDO70182.1 - 6.2e-137 456.5 7.6 5.5e-136 453.4 7.6 2.1 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 CDO70182.1 - 6.9e-19 68.2 0.5 1.8e-18 66.9 0.5 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CDO70182.1 - 4.9e-06 24.9 0.7 7.2e-06 24.4 0.7 1.1 1 0 0 1 1 1 1 Patched family HPIH PF13323.6 CDO70182.1 - 0.061 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain with HPIH motif VIT1 PF01988.19 CDO70183.1 - 0.4 10.5 2.4 22 4.8 1.1 2.4 2 0 0 2 2 2 0 VIT family 2-Hacid_dh_C PF02826.19 CDO70184.1 - 1e-41 142.2 0.0 1.5e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CDO70184.1 - 3.9e-11 42.8 0.0 1.3e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CDO70184.1 - 4.7e-05 23.6 0.0 0.00012 22.2 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CDO70184.1 - 0.00076 20.0 0.0 0.0015 19.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 CDO70184.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ion_trans_2 PF07885.16 CDO70185.1 - 3.4e-25 87.8 32.2 5.7e-14 51.8 7.0 3.2 3 0 0 3 3 3 2 Ion channel DUF2207 PF09972.9 CDO70185.1 - 0.045 12.5 2.5 1.6 7.4 1.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TOM13 PF08219.11 CDO70185.1 - 0.17 11.9 0.1 0.51 10.3 0.1 1.8 1 0 0 1 1 1 0 Outer membrane protein TOM13 7tm_1 PF00001.21 CDO70185.1 - 0.59 9.4 7.1 0.42 9.9 2.0 2.5 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Ctr PF04145.15 CDO70185.1 - 0.87 10.2 8.6 16 6.1 0.0 4.4 5 1 1 6 6 6 0 Ctr copper transporter family Transposase_21 PF02992.14 CDO70186.1 - 4.9e-12 45.5 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 TSC22 PF01166.18 CDO70188.1 - 0.029 14.7 0.0 0.093 13.1 0.0 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Med17 PF10156.9 CDO70189.1 - 0.14 10.9 2.2 0.14 10.8 2.2 1.0 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Aldo_ket_red PF00248.21 CDO70195.1 - 1.9e-46 158.6 0.0 3.3e-44 151.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CDO70196.1 - 5.9e-45 153.7 0.0 5.4e-34 117.7 0.0 2.3 1 1 1 2 2 2 2 Aldo/keto reductase family WD40 PF00400.32 CDO70196.1 - 2.4e-23 82.0 5.2 7.1e-06 26.7 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO70196.1 - 1.7e-06 28.2 0.0 1.5 9.1 0.0 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDO70196.1 - 0.01 15.2 0.0 0.05 12.9 0.0 2.0 2 1 0 3 3 3 0 WD40-like domain DUF5046 PF16465.5 CDO70196.1 - 0.01 15.3 0.2 0.25 10.7 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) PQQ_2 PF13360.6 CDO70196.1 - 0.056 13.0 0.4 0.2 11.2 0.4 1.9 1 1 0 1 1 1 0 PQQ-like domain Nup160 PF11715.8 CDO70196.1 - 0.2 10.3 0.4 1.1 7.8 0.1 2.3 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Hydrolase PF00702.26 CDO70197.1 - 8e-09 36.1 0.0 1.4e-08 35.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDO70197.1 - 5.1e-08 33.2 0.0 7.2e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDO70197.1 - 3.4e-05 23.8 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like TFA2_Winged_2 PF18121.1 CDO70197.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 HTH_47 PF16221.5 CDO70197.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 winged helix-turn-helix DUF3446 PF11928.8 CDO70199.1 - 5.4 7.4 16.9 30 5.0 16.9 2.3 1 0 0 1 1 1 0 Early growth response N-terminal domain MFS_1 PF07690.16 CDO70201.1 - 1.9e-09 36.9 45.0 1.5e-07 30.7 23.3 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Ribosomal_L7Ae PF01248.26 CDO70202.1 - 1.4e-22 79.2 0.8 2.5e-22 78.4 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 CDO70202.1 - 0.054 12.5 0.3 0.068 12.2 0.3 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) DHR10 PF18595.1 CDO70205.1 - 0.0047 17.0 1.8 0.0068 16.5 1.8 1.1 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain ADIP PF11559.8 CDO70205.1 - 0.044 13.9 1.0 0.067 13.3 1.0 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.6 CDO70205.1 - 0.081 13.4 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Ino80_Iec3 PF14612.6 CDO70205.1 - 0.096 13.3 1.3 0.2 12.3 1.3 1.4 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Sigma70_ner PF04546.13 CDO70205.1 - 0.11 12.4 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region SHE3 PF17078.5 CDO70205.1 - 0.13 12.0 0.1 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 AAA_13 PF13166.6 CDO70205.1 - 0.23 10.1 0.3 0.3 9.7 0.3 1.0 1 0 0 1 1 1 0 AAA domain PBP PF01161.20 CDO70206.1 - 4.7e-16 59.3 0.2 5.5e-16 59.1 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein APH PF01636.23 CDO70207.1 - 0.00051 20.0 0.1 0.0013 18.7 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO70207.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SAPS PF04499.15 CDO70210.1 - 0.29 9.9 4.3 0.7 8.6 4.3 1.6 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRM13 PF05206.14 CDO70210.1 - 2.4 7.6 6.2 9.5 5.6 6.2 2.0 1 0 0 1 1 1 0 Methyltransferase TRM13 Pkinase_fungal PF17667.1 CDO70211.1 - 2.3e-18 66.2 0.0 3e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LysM PF01476.20 CDO70211.1 - 1.9e-13 50.2 0.1 7.8e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 LysM domain Pkinase PF00069.25 CDO70211.1 - 0.039 13.3 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Dimer_Tnp_hAT PF05699.14 CDO70213.1 - 1.7e-14 53.4 0.1 3.9e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ABC_membrane_2 PF06472.15 CDO70214.1 - 1.8e-81 273.5 0.5 2.9e-81 272.8 0.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CDO70214.1 - 5.3e-17 62.6 0.0 1.2e-16 61.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CDO70214.1 - 9.3e-05 22.4 0.0 0.0004 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDO70214.1 - 0.0038 17.8 0.1 0.012 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CDO70214.1 - 0.046 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain SMC_N PF02463.19 CDO70214.1 - 0.058 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDO70214.1 - 0.081 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CDO70214.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_15 PF13175.6 CDO70214.1 - 0.28 10.9 0.0 0.49 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PRELI PF04707.14 CDO70215.1 - 1.1e-33 116.3 0.0 1.3e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family DUF4129 PF13559.6 CDO70215.1 - 0.046 14.0 0.1 0.15 12.4 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) B-block_TFIIIC PF04182.12 CDO70216.1 - 1.8e-09 37.6 0.1 2.2e-06 27.7 0.0 3.8 4 0 0 4 4 4 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 CDO70216.1 - 0.0004 19.9 2.7 0.14 11.8 0.0 5.0 5 0 0 5 5 5 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 CDO70216.1 - 0.00052 20.0 0.0 16 5.7 0.0 5.7 6 0 0 6 6 6 1 Helix-turn-helix domain MarR_2 PF12802.7 CDO70216.1 - 0.0039 17.0 0.1 0.53 10.2 0.0 4.3 5 0 0 5 5 5 1 MarR family RPA_C PF08784.11 CDO70216.1 - 0.025 15.2 0.0 28 5.4 0.0 4.6 5 0 0 5 5 5 0 Replication protein A C terminal MarR PF01047.22 CDO70216.1 - 0.05 13.5 0.0 0.54 10.2 0.0 2.7 2 0 0 2 2 2 0 MarR family Cwf_Cwc_15 PF04889.12 CDO70217.1 - 0.0042 16.9 6.2 0.0068 16.2 6.2 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein ORC_WH_C PF18137.1 CDO70217.1 - 0.0087 16.1 1.4 0.017 15.2 1.4 1.4 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal FAM176 PF14851.6 CDO70217.1 - 0.0088 15.7 1.9 0.1 12.2 2.4 2.2 2 0 0 2 2 2 1 FAM176 family PPP4R2 PF09184.11 CDO70217.1 - 0.013 15.1 8.1 0.019 14.6 8.1 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 CDO70217.1 - 0.014 14.7 7.6 0.021 14.1 7.6 1.2 1 0 0 1 1 1 0 NOA36 protein MAM33 PF02330.16 CDO70217.1 - 0.014 15.3 0.6 0.022 14.7 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial glycoprotein Na_trans_assoc PF06512.13 CDO70217.1 - 0.027 14.8 2.0 0.045 14.0 2.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated CDC27 PF09507.10 CDO70217.1 - 0.058 12.8 6.4 0.081 12.3 6.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RXT2_N PF08595.11 CDO70217.1 - 0.062 13.3 2.9 0.11 12.6 2.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Myc_N PF01056.18 CDO70217.1 - 0.084 12.8 7.9 0.13 12.2 7.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CNDH2_M PF16869.5 CDO70217.1 - 0.17 12.6 7.7 0.31 11.7 7.7 1.5 1 0 0 1 1 1 0 PF16858 ANAPC15 PF15243.6 CDO70217.1 - 0.18 12.2 9.4 0.37 11.2 9.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 TFIIA PF03153.13 CDO70217.1 - 0.19 11.7 6.3 0.27 11.2 6.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 CDO70217.1 - 0.34 9.1 4.6 0.48 8.6 4.6 1.2 1 0 0 1 1 1 0 Nop14-like family Imm5 PF14423.6 CDO70217.1 - 2.3 8.4 4.0 5.7 7.1 4.0 1.7 1 0 0 1 1 1 0 Immunity protein Imm5 DUF4611 PF15387.6 CDO70217.1 - 3 8.1 9.2 7.1 6.9 9.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleo_P87 PF07267.11 CDO70217.1 - 3.4 6.4 4.7 4.7 5.9 4.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DNA_pol_phi PF04931.13 CDO70217.1 - 6.8 4.7 14.4 11 4.0 14.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi PRELI PF04707.14 CDO70218.1 - 2.7e-34 118.3 0.0 3.4e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Lactamase_B_2 PF12706.7 CDO70220.1 - 5.7e-12 45.6 0.0 0.0022 17.6 0.0 3.4 3 0 0 3 3 3 3 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDO70220.1 - 0.00016 21.7 0.1 0.00049 20.2 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily MMR_HSR1_Xtn PF16897.5 CDO70221.1 - 1.5e-33 115.0 0.2 2.4e-33 114.3 0.2 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CDO70221.1 - 0.00015 21.8 0.2 0.012 15.7 0.2 2.4 1 1 1 2 2 2 2 TGS domain Pkinase PF00069.25 CDO70222.1 - 2.5e-63 213.9 0.0 4.3e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70222.1 - 4e-34 118.1 0.0 1.8e-24 86.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDO70222.1 - 0.0077 15.6 0.1 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like MCM PF00493.23 CDO70223.1 - 2.1e-97 324.6 0.2 3.1e-97 324.1 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDO70223.1 - 6.7e-35 119.7 0.0 1.1e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDO70223.1 - 6e-22 77.9 0.3 1.2e-21 76.9 0.3 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CDO70223.1 - 3.2e-15 56.6 0.7 1.2e-14 54.8 0.2 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDO70223.1 - 9.6e-08 31.7 0.0 1.3e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDO70223.1 - 0.002 18.0 0.0 0.0079 16.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDO70223.1 - 0.0066 16.2 0.1 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain WD40 PF00400.32 CDO70225.1 - 6.5e-30 102.7 13.6 1.3e-07 32.1 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO70225.1 - 3e-08 33.9 0.1 1.8 8.9 0.0 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CDO70225.1 - 0.0071 15.9 0.1 0.39 10.3 0.0 2.7 2 1 1 3 3 3 2 PQQ-like domain Mito_carr PF00153.27 CDO70226.1 - 1.2e-16 60.3 0.0 8e-07 28.9 0.0 2.5 2 1 0 2 2 2 2 Mitochondrial carrier protein RINT1_TIP1 PF04437.13 CDO70227.1 - 2e-88 297.5 0.0 6.6e-88 295.8 0.0 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family DUF745 PF05335.13 CDO70227.1 - 0.048 13.4 6.7 0.29 10.8 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) SesA PF17107.5 CDO70227.1 - 0.076 13.2 6.5 1.7 8.8 0.4 3.3 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF5304 PF17230.2 CDO70227.1 - 0.19 12.0 5.8 7.2 6.8 0.1 4.0 3 1 1 4 4 4 0 Family of unknown function (DUF5304) NT5C PF06941.12 CDO70228.1 - 1.1e-05 25.4 2.3 0.00094 19.1 0.0 3.5 2 1 2 4 4 4 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 CDO70228.1 - 8.8e-05 22.7 0.0 0.00024 21.3 0.0 1.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 CDO70228.1 - 0.00037 20.3 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 CDO70228.1 - 0.0023 18.3 0.0 0.0052 17.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 CDO70228.1 - 0.0039 16.8 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.6 CDO70228.1 - 0.0075 16.4 0.0 0.015 15.4 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 CDO70228.1 - 0.017 15.5 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDO70228.1 - 0.088 12.5 0.0 0.19 11.5 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase p450 PF00067.22 CDO70229.1 - 2.4e-56 191.4 0.0 4.5e-40 137.8 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Pro_CA PF00484.19 CDO70230.1 - 4.6e-15 56.2 0.1 1.5e-14 54.6 0.0 1.8 2 0 0 2 2 2 1 Carbonic anhydrase ThiI PF02568.14 CDO70230.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) RIC1 PF07064.13 CDO70231.1 - 9.8e-99 329.8 0.1 1.4e-98 329.4 0.1 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 CDO70231.1 - 0.0014 18.9 0.1 2.9 8.2 0.1 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CDO70231.1 - 0.0039 17.1 1.8 1.6 8.7 0.0 3.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat SMP PF04927.12 CDO70231.1 - 0.17 12.3 0.1 0.4 11.2 0.1 1.5 1 0 0 1 1 1 0 Seed maturation protein DIOX_N PF14226.6 CDO70232.1 - 9e-05 23.2 0.2 0.00093 19.9 0.0 2.4 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO70232.1 - 0.0081 16.6 0.0 0.051 14.1 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_28 PF03033.20 CDO70233.1 - 1.4e-27 96.4 0.0 4.2e-27 94.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 CDO70233.1 - 3.9e-24 84.7 0.2 4e-17 62.1 0.0 3.4 3 1 0 3 3 3 2 GRAM domain PH PF00169.29 CDO70233.1 - 6.7e-13 49.1 0.1 2.7e-11 43.9 0.2 2.8 2 0 0 2 2 2 1 PH domain UDPGT PF00201.18 CDO70233.1 - 2.1e-06 26.9 0.0 3.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 CDO70233.1 - 0.00029 21.2 1.8 0.016 15.6 1.8 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CDO70233.1 - 0.012 15.9 0.1 0.027 14.8 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Glyco_tran_28_C PF04101.16 CDO70233.1 - 0.038 14.0 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PH_6 PF15406.6 CDO70233.1 - 0.044 14.1 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 CDO70233.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region SUR7 PF06687.12 CDO70234.1 - 1.1e-14 54.5 5.6 1.5e-14 54.2 5.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF1435 PF07256.12 CDO70234.1 - 0.11 12.6 0.4 0.11 12.6 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) Glyco_hydro_72 PF03198.14 CDO70235.1 - 7.8e-88 294.7 0.0 1.2e-87 294.1 0.0 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CDO70235.1 - 1.9e-19 70.1 0.8 5.2e-19 68.7 0.8 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 CDO70235.1 - 0.011 15.2 0.1 0.022 14.2 0.1 1.4 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Polysacc_deac_1 PF01522.21 CDO70236.1 - 3.8e-30 104.3 0.0 6.8e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CDO70236.1 - 0.0085 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 NAP PF00956.18 CDO70237.1 - 3.2e-26 92.1 2.3 3.2e-26 92.1 2.3 3.2 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) GOLD_2 PF13897.6 CDO70237.1 - 0.028 14.9 2.9 0.19 12.2 0.8 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DicB PF05358.11 CDO70237.1 - 0.071 13.3 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 DicB protein YL1 PF05764.13 CDO70237.1 - 0.84 9.7 10.0 0.065 13.3 5.7 1.5 2 0 0 2 2 2 0 YL1 nuclear protein Syja_N PF02383.18 CDO70238.1 - 1.7e-89 300.3 0.1 2.3e-89 299.9 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain LRR_9 PF14580.6 CDO70239.1 - 2.7e-61 206.1 0.4 4.1e-61 205.5 0.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CDO70239.1 - 2.9e-08 33.8 16.1 2.1e-05 24.8 5.3 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDO70239.1 - 1.7e-07 30.9 5.5 1.7e-07 30.9 5.5 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 CDO70239.1 - 5.5 7.9 7.8 56 4.9 0.2 4.3 5 1 0 5 5 5 0 Leucine Rich Repeat DUF4149 PF13664.6 CDO70240.1 - 2.8e-21 75.7 2.5 2.8e-21 75.7 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 CDO70240.1 - 0.00093 19.5 1.0 0.0012 19.2 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) PY_rept_46 PF09689.10 CDO70240.1 - 0.038 14.5 0.2 0.064 13.8 0.2 1.2 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) MitMem_reg PF13012.6 CDO70241.1 - 4.7e-25 88.2 0.2 7.2e-25 87.6 0.2 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CDO70241.1 - 1.4e-11 44.4 0.0 2.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HAUS4 PF14735.6 CDO70241.1 - 0.11 12.2 0.3 0.16 11.6 0.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 MCM PF00493.23 CDO70242.1 - 1.2e-103 345.1 0.1 5.4e-103 342.9 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 CDO70242.1 - 1e-33 115.8 0.0 2.6e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CDO70242.1 - 6.3e-29 100.2 1.0 1.5e-28 99.0 1.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CDO70242.1 - 5.5e-16 59.0 0.2 2.5e-15 56.9 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDO70242.1 - 7.4e-07 28.8 0.0 0.00024 20.6 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDO70242.1 - 8e-05 22.7 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDO70242.1 - 0.00033 20.5 0.1 0.0021 17.9 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 CDO70242.1 - 0.0063 17.1 1.1 0.049 14.3 0.2 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 CDO70242.1 - 0.061 13.7 0.0 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3128 PF11326.8 CDO70243.1 - 8.4e-20 70.9 0.4 1.1e-19 70.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Catalase PF00199.19 CDO70245.1 - 2.1e-152 507.7 0.1 3.3e-151 503.7 0.1 2.0 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CDO70245.1 - 9e-18 64.3 0.1 1.8e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 CDO70245.1 - 1.5e-16 60.4 0.2 5.1e-16 58.7 0.2 2.0 1 1 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 CDO70245.1 - 5.6e-10 39.3 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family zf-C2H2 PF00096.26 CDO70246.1 - 9.7e-07 28.9 0.4 9.7e-07 28.9 0.4 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO70246.1 - 6.9e-05 23.1 6.7 0.038 14.4 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDO70246.1 - 0.00031 21.3 8.6 0.003 18.2 0.2 3.8 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDO70246.1 - 0.094 13.0 0.1 0.094 13.0 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3889 PF13028.6 CDO70246.1 - 0.22 11.5 1.0 0.6 10.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) Peptidase_S10 PF00450.22 CDO70247.1 - 3.8e-88 296.7 2.2 4.6e-88 296.4 2.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Nramp PF01566.18 CDO70248.1 - 1.7e-73 247.6 26.3 3.4e-39 134.8 6.8 2.5 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein Med6 PF04934.14 CDO70249.1 - 1.1e-38 132.1 0.0 1.6e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Clat_adaptor_s PF01217.20 CDO70250.1 - 2.7e-40 137.6 0.2 1.1e-39 135.6 0.2 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain EHN PF06441.12 CDO70251.1 - 5.3e-28 97.5 2.1 6.1e-28 97.3 0.1 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CDO70251.1 - 3.8e-06 26.7 0.2 6.9e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO70251.1 - 0.11 11.7 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO70251.1 - 0.42 11.2 4.8 1.7 9.2 4.8 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family CBM_5_12 PF02839.14 CDO70253.1 - 2.7e-05 24.5 16.9 0.0035 17.8 6.6 3.2 2 0 0 2 2 2 2 Carbohydrate binding domain CBM_5_12_2 PF14600.6 CDO70253.1 - 0.0072 16.2 12.0 0.013 15.4 3.4 2.4 2 0 0 2 2 2 2 Cellulose-binding domain Glyco_hydro_18 PF00704.28 CDO70254.1 - 4.2e-05 23.4 0.1 4.2e-05 23.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 CDO70255.1 - 2e-62 211.0 0.0 2.4e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70255.1 - 1.4e-19 70.4 0.0 2e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO70255.1 - 1.1e-05 25.4 1.0 0.00014 21.8 0.2 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO70255.1 - 0.0063 15.3 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDO70255.1 - 0.027 13.8 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDO70255.1 - 0.046 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DnaJ_C PF01556.18 CDO70256.1 - 8.7e-39 133.0 0.0 1.2e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDO70256.1 - 8.4e-24 83.5 3.5 1.3e-23 82.9 3.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDO70256.1 - 5.6e-11 42.7 15.4 5.6e-11 42.7 15.4 1.9 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 CDO70256.1 - 0.13 12.3 18.2 0.69 9.9 4.0 3.0 1 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein MFS_1 PF07690.16 CDO70257.1 - 6e-39 134.0 46.1 2e-37 128.9 46.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO70257.1 - 8.4e-09 34.8 9.1 8.4e-09 34.8 9.1 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter CclA_1 PF16942.5 CDO70257.1 - 0.15 12.4 5.5 0.067 13.5 2.1 2.3 2 0 0 2 2 2 0 Putative cyclic bacteriocin Choline_kinase PF01633.20 CDO70258.1 - 1.4e-51 175.1 0.0 1.9e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CDO70258.1 - 1.8e-13 51.0 2.7 2e-13 50.8 1.6 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-CCCH PF00642.24 CDO70259.1 - 9.3e-11 41.4 2.6 9.3e-11 41.4 2.6 2.9 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDO70259.1 - 1.4e-06 28.1 3.8 2.6e-06 27.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CDO70259.1 - 6.2e-06 25.9 0.9 6.2e-06 25.9 0.9 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CDO70259.1 - 0.09 13.3 0.2 0.09 13.3 0.2 1.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger BLM10_mid PF16507.5 CDO70260.1 - 1.6e-176 588.1 0.0 2.8e-176 587.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 CDO70260.1 - 2.1e-26 91.6 0.1 5.6e-25 87.1 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 CDO70260.1 - 8.1e-05 22.6 6.6 0.02 15.1 0.1 6.1 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 CDO70260.1 - 0.00034 20.9 0.0 0.1 13.0 0.0 3.9 3 1 1 4 4 4 1 HEAT repeats TAF6_C PF07571.13 CDO70260.1 - 0.0093 16.3 0.0 0.073 13.4 0.0 2.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain BLM10_N PF16547.5 CDO70260.1 - 0.018 15.4 0.0 0.046 14.0 0.0 1.7 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Cnd1 PF12717.7 CDO70260.1 - 0.14 12.1 0.3 0.88 9.6 0.1 2.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Chalcone_2 PF16035.5 CDO70261.1 - 1.7e-27 96.6 0.2 7e-16 58.6 0.0 2.3 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 CDO70261.1 - 0.032 14.3 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Chalcone isomerase-like TIM21 PF08294.11 CDO70262.1 - 5.2e-22 78.3 0.0 3.8e-18 65.7 0.0 2.2 2 0 0 2 2 2 2 TIM21 ATP-synt_F PF01990.17 CDO70263.1 - 5.5e-33 113.2 0.1 6.4e-33 113.0 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit AhpC-TSA PF00578.21 CDO70263.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family DXP_synthase_N PF13292.6 CDO70263.1 - 0.018 14.3 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase SGT1 PF07093.11 CDO70264.1 - 1.3e-95 321.1 15.0 2.2e-95 320.3 9.0 3.1 2 1 0 2 2 2 1 SGT1 protein zf-C3HC4_3 PF13920.6 CDO70266.1 - 5.5e-09 35.8 7.0 7.6e-09 35.3 7.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDO70266.1 - 1.4e-08 34.5 10.5 2.2e-08 33.8 10.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO70266.1 - 2.5e-08 33.6 8.8 3.9e-08 33.0 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO70266.1 - 1.2e-07 31.9 9.0 1.8e-07 31.3 9.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CDO70266.1 - 9.8e-06 25.5 7.4 1.1e-05 25.4 6.1 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDO70266.1 - 1.6e-05 24.8 10.0 0.00017 21.5 11.0 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDO70266.1 - 8.8e-05 22.6 10.5 0.00016 21.8 10.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDO70266.1 - 0.0019 18.0 8.8 0.1 12.4 9.9 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDO70266.1 - 0.043 13.9 1.8 0.078 13.0 1.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 CDO70266.1 - 0.16 11.9 6.1 0.27 11.1 6.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein GAGA PF09237.11 CDO70266.1 - 0.18 11.6 6.6 1.4 8.8 0.6 2.7 3 0 0 3 3 3 0 GAGA factor zf-MIZ PF02891.20 CDO70266.1 - 0.27 11.0 6.0 0.47 10.2 6.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CDO70266.1 - 0.38 10.6 3.1 0.69 9.8 3.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 CDO70266.1 - 0.83 10.0 8.6 8 6.8 8.7 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CDO70266.1 - 1.2 9.0 8.2 7.4 6.4 8.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Translin PF01997.16 CDO70268.1 - 2.2e-73 246.6 0.0 2.6e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Translin family SesA PF17107.5 CDO70268.1 - 0.022 14.9 0.1 5.7 7.1 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DcpS_C PF11969.8 CDO70269.1 - 7.1e-05 23.3 0.4 0.00019 21.9 0.4 1.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3875 PF12991.7 CDO70269.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3875) BLM10_mid PF16507.5 CDO70270.1 - 1.2e-153 512.5 0.0 5.5e-137 457.6 0.0 3.0 2 1 1 3 3 3 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 CDO70270.1 - 3.6e-31 106.9 0.8 1.6e-30 104.9 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 CDO70270.1 - 4.7e-06 26.4 1.8 0.029 14.6 0.1 4.9 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 CDO70270.1 - 0.012 16.0 1.5 1.8 9.0 0.0 4.6 5 0 0 5 5 5 0 HEAT repeats HD_assoc PF13286.6 CDO70270.1 - 0.017 15.6 0.0 0.22 12.1 0.0 2.5 2 0 0 2 2 2 0 Phosphohydrolase-associated domain Arm PF00514.23 CDO70270.1 - 0.067 13.3 0.1 0.72 10.0 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF2524 PF10732.9 CDO70271.1 - 0.12 12.7 0.1 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) ERM PF00769.19 CDO70272.1 - 0.054 13.3 16.6 0.13 12.1 16.6 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HAUS6_N PF14661.6 CDO70272.1 - 0.78 9.3 6.5 1.3 8.6 6.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus GBP_C PF02841.14 CDO70272.1 - 8.3 5.7 14.1 15 4.9 14.1 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain ATP-grasp_2 PF08442.10 CDO70273.1 - 4.2e-70 235.4 0.2 8.5e-70 234.4 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 CDO70273.1 - 3.3e-26 91.9 0.0 5.7e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CDO70273.1 - 2.5e-12 46.8 0.0 1.1e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 CDO70273.1 - 6.1e-06 26.1 0.1 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 CDO70273.1 - 0.081 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Hist_deacetyl PF00850.19 CDO70274.1 - 9.8e-83 278.1 0.0 1.5e-82 277.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain XPA_N PF01286.18 CDO70275.1 - 0.00053 20.0 5.9 0.00053 20.0 5.9 2.9 3 0 0 3 3 3 2 XPA protein N-terminal 4HBT_3 PF13622.6 CDO70276.1 - 6.3e-24 85.6 0.3 7.7e-11 42.7 0.2 2.0 1 1 1 2 2 2 2 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CDO70276.1 - 1.1e-05 25.3 0.0 0.019 14.8 0.0 2.5 2 1 0 2 2 2 2 Acyl-CoA thioesterase Ribosomal_S27e PF01667.17 CDO70277.1 - 2.5e-29 100.7 1.7 3e-29 100.5 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 CDO70277.1 - 0.0073 15.8 1.6 0.011 15.2 1.6 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.21 CDO70277.1 - 0.058 13.6 0.5 0.079 13.2 0.5 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zinc_ribbon_4 PF13717.6 CDO70277.1 - 0.12 12.4 1.4 1.8 8.5 1.4 2.3 1 1 0 1 1 1 0 zinc-ribbon domain DUF678 PF05077.12 CDO70277.1 - 0.12 12.6 4.9 0.18 11.9 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF678) Prok-RING_1 PF14446.6 CDO70277.1 - 0.18 11.8 2.3 0.3 11.1 2.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2HC5 PF06221.13 CDO70277.1 - 0.19 11.7 5.0 0.18 11.8 3.5 1.8 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type BTG PF07742.12 CDO70278.1 - 5.7e-17 61.6 0.0 2.9e-16 59.3 0.0 2.1 2 1 0 2 2 2 1 BTG family BATS PF06968.13 CDO70279.1 - 2.7e-21 75.5 0.2 1.2e-20 73.4 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 CDO70279.1 - 3.9e-17 63.1 0.0 7.3e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily BCAS2 PF05700.11 CDO70280.1 - 2.5e-50 171.1 14.1 1.6e-49 168.5 9.2 1.9 1 1 1 2 2 2 2 Breast carcinoma amplified sequence 2 (BCAS2) Complex1_30kDa PF00329.19 CDO70281.1 - 1.2e-44 151.8 0.0 1.7e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF2087 PF09860.9 CDO70281.1 - 0.078 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF5427 PF10310.9 CDO70282.1 - 1.3e-60 205.7 6.2 6e-58 196.9 0.2 2.3 1 1 1 2 2 2 2 Family of unknown function (DUF5427) Chromo PF00385.24 CDO70283.1 - 4.8e-10 39.2 1.8 9.1e-10 38.3 1.8 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tim17 PF02466.19 CDO70284.1 - 2.6e-14 53.5 0.4 5.4e-14 52.5 0.2 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 CDO70284.1 - 0.09 12.9 2.0 7.8 6.7 0.1 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5518) Ras PF00071.22 CDO70285.1 - 1.9e-38 131.6 0.3 2.3e-38 131.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO70285.1 - 1.1e-08 35.4 0.1 1.8e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CDO70285.1 - 0.00036 20.1 0.0 0.00068 19.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CDO70285.1 - 0.0026 17.3 0.1 0.003 17.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDO70285.1 - 0.013 15.4 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase ACOX PF01756.19 CDO70286.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA oxidase AbiEii PF08843.11 CDO70287.1 - 0.043 13.8 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system UBM PF14377.6 CDO70288.1 - 0.0081 15.6 0.3 0.021 14.2 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin binding region RVT_1 PF00078.27 CDO70290.1 - 3e-21 75.9 0.0 1.7e-18 66.9 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO70290.1 - 1.7e-09 38.0 0.0 3.3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO70290.1 - 0.0025 18.5 0.5 0.0067 17.1 0.5 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase UPF0016 PF01169.19 CDO70291.1 - 3.1e-44 149.2 14.3 1.4e-23 83.0 3.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 OFeT_1 PF16955.5 CDO70291.1 - 8.3e-06 25.6 2.0 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron uptake permease, iron-lead transporter TauE PF01925.19 CDO70291.1 - 0.0015 18.2 4.7 0.028 14.1 0.0 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE Mntp PF02659.15 CDO70291.1 - 0.0033 17.2 0.6 0.049 13.4 0.0 2.2 2 0 0 2 2 2 1 Putative manganese efflux pump TerC PF03741.16 CDO70291.1 - 0.0063 16.2 5.5 0.014 15.0 0.1 2.6 2 1 0 2 2 2 1 Integral membrane protein TerC family LysE PF01810.18 CDO70291.1 - 1.1 8.6 12.9 1.8 8.0 2.1 2.8 2 1 0 2 2 2 0 LysE type translocator PNP_UDP_1 PF01048.20 CDO70292.1 - 1.4e-24 86.7 0.0 2.4e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_tran_WecB PF03808.13 CDO70292.1 - 0.017 15.1 0.1 0.35 10.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family HMG_box PF00505.19 CDO70293.1 - 1.6e-13 50.8 4.2 3.4e-13 49.8 4.2 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO70293.1 - 9.1e-12 45.4 2.1 1.9e-11 44.4 2.1 1.5 1 0 0 1 1 1 1 HMG-box domain adh_short_C2 PF13561.6 CDO70294.1 - 2.7e-51 174.4 1.1 3.3e-51 174.1 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO70294.1 - 2.2e-35 121.9 0.9 2.8e-35 121.6 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO70294.1 - 8.5e-10 38.8 0.3 1.2e-09 38.3 0.3 1.1 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.21 CDO70294.1 - 0.014 14.9 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Glyco_hydro_31 PF01055.26 CDO70295.1 - 2.6e-146 488.3 1.0 3e-146 488.1 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 RVT_1 PF00078.27 CDO70296.1 - 1.9e-30 106.0 0.3 2.9e-30 105.5 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDO70296.1 - 3.9e-22 78.2 0.1 1.1e-21 76.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO70296.1 - 3.6e-16 59.4 0.0 8.6e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Retrotrans_gag PF03732.17 CDO70297.1 - 9.6e-12 45.0 0.0 2.4e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO70297.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Apt1 PF10351.9 CDO70297.1 - 8.1 5.2 8.3 11 4.7 8.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Retrotrans_gag PF03732.17 CDO70298.1 - 0.00025 21.3 0.1 0.00038 20.7 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO70298.1 - 0.0011 18.9 0.1 0.0025 17.7 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) Ric8 PF10165.9 CDO70301.1 - 2.7e-94 316.8 0.0 1.2e-77 262.0 0.0 2.0 2 0 0 2 2 2 2 Guanine nucleotide exchange factor synembryn His_Phos_1 PF00300.22 CDO70302.1 - 6e-12 45.7 0.2 7.4e-12 45.4 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Nop14 PF04147.12 CDO70305.1 - 0.13 10.4 6.8 0.14 10.3 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CDO70305.1 - 0.29 10.5 8.7 0.32 10.4 8.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CDO70305.1 - 0.34 9.1 8.6 0.38 9.0 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 CDO70305.1 - 2.9 7.6 6.5 4.6 6.9 6.5 1.3 1 0 0 1 1 1 0 FAM176 family SAPS PF04499.15 CDO70305.1 - 3 6.5 7.4 3.2 6.4 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macoilin PF09726.9 CDO70305.1 - 3 6.3 17.6 3.3 6.1 17.6 1.0 1 0 0 1 1 1 0 Macoilin family SURF2 PF05477.11 CDO70305.1 - 5 6.7 9.0 6.7 6.3 9.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PNISR PF15996.5 CDO70305.1 - 7 6.9 9.3 8.6 6.6 9.3 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Menin PF05053.13 CDO70305.1 - 8.8 4.5 10.8 11 4.3 10.8 1.2 1 0 0 1 1 1 0 Menin CobT PF06213.12 CDO70305.1 - 9.4 5.5 11.7 12 5.2 11.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DnaJ PF00226.31 CDO70306.1 - 4.2e-16 58.8 0.2 8.8e-16 57.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 CDO70306.1 - 2.2e-14 53.3 0.0 6.4e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 Sec63 Brl domain p450 PF00067.22 CDO70307.1 - 2.4e-07 29.9 0.0 7.2e-07 28.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 YbjM PF11045.8 CDO70307.1 - 0.11 12.7 0.5 0.18 12.0 0.5 1.3 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae RA PF00788.23 CDO70308.1 - 2.8e-11 43.9 0.0 7.9e-09 36.0 0.0 3.5 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 CDO70308.1 - 1.1e-06 28.1 0.4 2.9e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CDO70308.1 - 0.00073 19.3 0.1 0.0023 17.8 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain DUF2798 PF11391.8 CDO70309.1 - 0.099 12.7 1.1 0.17 11.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) CLP1_P PF16575.5 CDO70310.1 - 4.1e-36 124.5 0.0 1.1e-35 123.2 0.0 1.7 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 CDO70310.1 - 0.02 14.9 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDO70310.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DNA_pol3_delta2 PF13177.6 CDO70310.1 - 0.17 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Nucleo_P87 PF07267.11 CDO70310.1 - 0.72 8.6 11.2 3.9 6.2 11.7 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 ORC6 PF05460.13 CDO70310.1 - 4 6.6 13.8 6.3 6.0 13.8 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) WGG PF10273.9 CDO70311.1 - 7.3e-27 93.8 0.1 1.4e-26 92.9 0.1 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Ldh_1_C PF02866.18 CDO70312.1 - 3.2e-51 173.6 0.0 1.2e-50 171.7 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CDO70312.1 - 1.9e-36 125.2 0.4 6.8e-23 81.3 0.1 2.3 1 1 1 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CDO70312.1 - 0.013 15.9 1.3 0.088 13.2 0.1 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CDO70312.1 - 0.043 13.1 0.4 4.6 6.6 0.0 2.7 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Cyclin_N PF00134.23 CDO70314.1 - 3.7e-06 26.7 0.0 5.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-C4H2 PF10146.9 CDO70315.1 - 8.4e-10 39.3 6.2 1.1e-09 38.9 6.2 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein DUF3450 PF11932.8 CDO70315.1 - 0.0027 17.1 8.8 0.0037 16.6 8.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TMPIT PF07851.13 CDO70315.1 - 0.083 12.1 4.6 0.11 11.7 4.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Laminin_II PF06009.12 CDO70315.1 - 0.27 11.3 8.6 0.95 9.5 7.8 1.9 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 CDO70315.1 - 0.42 10.6 3.8 0.64 10.1 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4972 PF16342.5 CDO70315.1 - 0.6 9.8 5.7 1.5 8.5 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) FAM76 PF16046.5 CDO70315.1 - 1 8.6 8.4 1.5 8.1 8.4 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1690 PF07956.11 CDO70315.1 - 1.4 9.3 15.0 1.7 9.0 1.6 2.9 2 1 1 3 3 3 0 Protein of Unknown function (DUF1690) BshC PF10079.9 CDO70315.1 - 2.3 6.9 9.1 2.8 6.6 9.1 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Peptidase_S46 PF10459.9 CDO70315.1 - 2.4 6.7 8.1 3 6.4 8.1 1.0 1 0 0 1 1 1 0 Peptidase S46 DivIC PF04977.15 CDO70315.1 - 2.4 8.0 12.6 8.1 6.3 6.6 2.7 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.9 CDO70315.1 - 2.6 7.0 14.0 3.5 6.6 14.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 CDO70315.1 - 2.9 5.7 4.5 3.1 5.6 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 CDO70315.1 - 3.7 7.3 10.1 12 5.7 10.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 CDO70315.1 - 8.7 7.0 10.2 30 5.3 0.8 2.2 1 1 1 2 2 2 0 Initiation control protein YabA GPI-anchored PF10342.9 CDO70316.1 - 0.0053 17.5 0.0 0.014 16.2 0.0 1.6 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 CDO70317.1 - 1.7e-05 25.5 0.0 2.2e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-C3HC4_3 PF13920.6 CDO70318.1 - 5e-09 35.9 16.3 1.1e-08 34.7 16.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDO70318.1 - 0.01 15.6 14.9 0.02 14.7 14.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TFIIA PF03153.13 CDO70318.1 - 0.23 11.4 1.7 0.37 10.7 1.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HSF_DNA-bind PF00447.17 CDO70320.1 - 1.2e-32 112.4 3.3 3.2e-32 111.0 3.3 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding DUF812 PF05667.11 CDO70320.1 - 0.00046 19.2 1.6 0.00061 18.8 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CENP-Q PF13094.6 CDO70320.1 - 0.0046 17.2 0.3 0.0046 17.2 0.3 2.4 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Use1 PF09753.9 CDO70320.1 - 0.006 16.3 1.3 0.006 16.3 1.3 2.1 2 0 0 2 2 2 1 Membrane fusion protein Use1 ATG16 PF08614.11 CDO70320.1 - 0.018 15.3 1.0 0.018 15.3 1.0 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CDO70320.1 - 0.018 15.6 1.9 0.018 15.6 1.9 1.8 2 1 0 2 2 2 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 CDO70320.1 - 0.022 14.8 0.4 0.042 13.9 0.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 CDO70320.1 - 0.027 13.8 1.7 0.044 13.1 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2293 PF10056.9 CDO70320.1 - 0.037 14.3 0.4 0.082 13.2 0.4 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) Goodbye PF17109.5 CDO70320.1 - 0.037 14.5 1.1 0.068 13.6 0.2 1.8 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain FliD_C PF07195.12 CDO70320.1 - 0.047 13.1 1.3 0.35 10.2 0.5 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Snapin_Pallidin PF14712.6 CDO70320.1 - 0.24 11.8 3.9 0.24 11.8 2.0 2.0 2 0 0 2 2 2 0 Snapin/Pallidin DivIC PF04977.15 CDO70320.1 - 0.29 10.9 1.5 0.54 10.1 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator Fib_alpha PF08702.10 CDO70320.1 - 0.92 9.7 4.5 0.29 11.3 0.9 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CPSF73-100_C PF11718.8 CDO70320.1 - 7.3 6.1 7.5 13 5.2 7.5 1.6 1 1 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Pkinase_fungal PF17667.1 CDO70322.1 - 3.3e-22 78.9 0.0 4.8e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RVT_1 PF00078.27 CDO70323.1 - 6e-29 101.1 0.0 9.6e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO70323.1 - 1.1e-10 41.3 0.0 2.6e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 CDO70323.1 - 4.8e-07 30.0 0.0 1.5e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 RNase H Exo_endo_phos PF03372.23 CDO70323.1 - 0.018 14.6 0.3 0.08 12.5 0.3 2.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Pkinase_fungal PF17667.1 CDO70324.1 - 3.9e-46 157.7 0.0 8.4e-46 156.5 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase zf-C2H2 PF00096.26 CDO70325.1 - 8.5e-06 26.0 1.2 0.014 15.8 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO70325.1 - 6.8e-05 23.4 1.4 0.09 13.7 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDO70325.1 - 0.0096 16.2 0.8 0.096 13.0 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CDO70325.1 - 0.1 12.9 1.8 0.57 10.5 1.9 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CDO70325.1 - 0.23 11.8 1.4 3.3 8.1 1.3 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Abhydrolase_6 PF12697.7 CDO70326.1 - 1.3e-06 29.2 10.1 1.5e-06 29.0 5.2 2.6 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDO70326.1 - 0.00069 19.3 0.0 0.00093 18.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CDO70326.1 - 0.0013 18.7 0.4 0.0046 16.8 0.1 1.9 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.12 CDO70326.1 - 0.021 14.3 0.0 0.045 13.3 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.7 CDO70326.1 - 0.22 10.4 0.1 0.48 9.3 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme NAD_binding_10 PF13460.6 CDO70327.1 - 0.002 18.0 0.0 1.1 9.2 0.0 2.1 1 1 1 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 CDO70327.1 - 0.0084 15.6 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.16 CDO70327.1 - 0.014 15.0 0.0 0.036 13.7 0.0 1.6 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 CDO70327.1 - 0.082 12.3 0.1 0.096 12.1 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ATP-synt_J PF04911.12 CDO70328.1 - 4.5e-22 77.4 0.2 4.5e-22 77.4 0.2 1.7 2 0 0 2 2 2 1 ATP synthase j chain Clathrin PF00637.20 CDO70329.1 - 7.3e-17 61.6 0.0 7.5e-12 45.3 0.4 2.9 3 0 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.8 CDO70329.1 - 3.8e-09 36.6 0.2 7e-09 35.8 0.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 CDO70329.1 - 1.7e-08 34.3 8.0 2.8e-08 33.6 8.0 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 CDO70329.1 - 0.003 17.4 8.4 0.0051 16.6 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO70329.1 - 0.019 15.3 7.4 0.035 14.4 7.4 1.5 1 0 0 1 1 1 0 Ring finger domain TPR_11 PF13414.6 CDO70329.1 - 0.06 13.0 0.2 0.2 11.4 0.2 1.9 1 0 0 1 1 1 0 TPR repeat ADK_lid PF05191.14 CDO70329.1 - 0.3 11.1 1.0 3.3 7.8 2.2 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-RING_5 PF14634.6 CDO70329.1 - 0.62 10.1 7.3 1.1 9.3 7.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDO70329.1 - 1.4 9.0 7.0 2.8 8.1 7.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger TPR_16 PF13432.6 CDO70329.1 - 2.2 9.0 8.9 12 6.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDO70329.1 - 2.3 8.5 4.2 5.5 7.4 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 CDO70329.1 - 2.9 8.2 7.6 5.6 7.3 7.6 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain NmrA PF05368.13 CDO70330.1 - 1e-44 152.9 0.0 1.2e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CDO70330.1 - 2.1e-17 63.6 0.0 2.9e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CDO70330.1 - 8.2e-05 21.7 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CDO70330.1 - 8.9e-05 22.1 0.0 0.0026 17.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CDO70330.1 - 0.0046 17.2 0.0 0.0096 16.2 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CDO70330.1 - 0.0058 16.9 0.0 0.014 15.7 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain KR PF08659.10 CDO70330.1 - 0.0089 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 CDO70330.1 - 0.043 13.9 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 CDO70330.1 - 0.048 14.1 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 CDO70330.1 - 0.063 14.0 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase BTB PF00651.31 CDO70331.1 - 3.3e-12 46.6 0.0 4e-05 23.8 0.0 3.5 3 0 0 3 3 3 2 BTB/POZ domain BTB PF00651.31 CDO70332.1 - 5e-05 23.5 0.0 0.00011 22.4 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain SMC_N PF02463.19 CDO70333.1 - 1.3e-53 181.7 0.0 3.7e-30 105.0 0.0 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDO70333.1 - 3.1e-30 104.9 0.1 2e-29 102.3 0.1 2.6 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CDO70333.1 - 4.6e-16 59.5 0.0 1.2e-10 41.7 0.0 4.0 2 2 1 3 3 2 1 AAA ATPase domain AAA_21 PF13304.6 CDO70333.1 - 1.1e-14 55.0 3.0 2.6e-06 27.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system NAD_binding_1 PF00175.21 CDO70333.1 - 9.1e-13 48.8 0.0 9.1e-13 48.8 0.0 3.9 4 0 0 4 4 3 1 Oxidoreductase NAD-binding domain Globin PF00042.22 CDO70333.1 - 5.3e-07 30.2 2.1 1.6e-06 28.6 0.1 2.7 2 0 0 2 2 2 1 Globin AAA_29 PF13555.6 CDO70333.1 - 6.2e-07 29.1 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 CDO70333.1 - 0.012 15.8 0.0 0.035 14.3 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NAD_binding_6 PF08030.12 CDO70333.1 - 0.028 14.5 0.0 0.37 10.9 0.0 3.0 2 0 0 2 2 2 0 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 CDO70333.1 - 0.082 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain AAA_22 PF13401.6 CDO70333.1 - 0.12 12.7 4.1 73 3.6 0.0 4.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CDO70333.1 - 0.35 11.4 0.0 0.35 11.4 0.0 5.6 4 1 1 5 5 5 0 ABC transporter ApoC-I PF04691.12 CDO70333.1 - 0.7 9.9 18.1 3.3 7.7 0.0 4.7 4 0 0 4 4 4 0 Apolipoprotein C-I (ApoC-1) CbiG_C PF01890.16 CDO70333.1 - 1.2 9.7 4.2 1.7 9.2 0.2 2.9 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus Coprogen_oxidas PF01218.18 CDO70333.1 - 1.7 7.2 5.5 0.32 9.7 0.0 2.6 3 0 0 3 3 3 0 Coproporphyrinogen III oxidase 4HBT PF03061.22 CDO70334.1 - 4.1e-07 30.2 0.4 6.7e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 CDO70334.1 - 0.017 15.4 1.3 0.024 14.9 1.3 1.3 1 1 0 1 1 1 0 Thioesterase-like superfamily MFS_1 PF07690.16 CDO70336.1 - 4e-38 131.3 34.0 5.4e-38 130.8 34.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO70336.1 - 1.8e-12 46.9 14.3 7e-12 44.9 14.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CDO70336.1 - 1.2e-07 30.6 0.9 1.7e-07 30.1 0.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Y_phosphatase3 PF13350.6 CDO70337.1 - 2.8e-59 200.9 0.1 3.2e-59 200.7 0.1 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CDO70337.1 - 3.2e-05 23.6 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 CDO70337.1 - 0.00022 20.8 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CDO70337.1 - 0.0062 16.7 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 CDO70337.1 - 0.011 15.5 0.1 0.034 14.0 0.1 2.0 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain KNOX2 PF03791.13 CDO70337.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 KNOX2 domain Peptidase_C14 PF00656.22 CDO70340.1 - 2.3e-36 126.0 0.1 3.5e-36 125.4 0.1 1.1 1 0 0 1 1 1 1 Caspase domain DUF5554 PF17709.1 CDO70340.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5554) Pkinase PF00069.25 CDO70341.1 - 3e-52 177.6 0.0 2.9e-51 174.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70341.1 - 2.4e-22 79.5 0.0 3.2e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO70341.1 - 0.0016 17.8 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDO70341.1 - 0.0073 16.3 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDO70341.1 - 0.043 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDO70341.1 - 0.05 12.5 0.0 0.13 11.2 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CDO70341.1 - 0.19 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FOXP-CC PF16159.5 CDO70345.1 - 0.063 13.9 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain DSPc PF00782.20 CDO70346.1 - 5.3e-05 23.0 0.0 5.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDO70346.1 - 0.0097 15.5 0.1 0.01 15.4 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CDO70346.1 - 0.073 12.7 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 CDO70346.1 - 0.19 11.7 1.2 0.23 11.4 0.8 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family RVT_3 PF13456.6 CDO70350.1 - 0.12 12.2 0.2 0.68 9.7 0.2 1.9 1 1 0 1 1 1 0 Reverse transcriptase-like PPR_2 PF13041.6 CDO70351.1 - 2.7e-40 136.3 0.0 3.3e-13 49.6 0.1 11.1 9 3 3 12 12 12 9 PPR repeat family PPR PF01535.20 CDO70351.1 - 1.4e-39 131.5 0.2 9e-05 22.5 0.0 12.6 13 0 0 13 13 13 6 PPR repeat PPR_1 PF12854.7 CDO70351.1 - 2.2e-29 100.9 0.0 7.3e-06 25.6 0.0 10.4 11 0 0 11 11 11 5 PPR repeat PPR_3 PF13812.6 CDO70351.1 - 1.6e-21 76.1 0.1 1.2e-09 38.1 0.0 8.0 6 2 2 8 8 8 3 Pentatricopeptide repeat domain PPR_long PF17177.4 CDO70351.1 - 5.9e-13 48.7 3.3 2e-09 37.2 0.4 4.2 4 1 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 CDO70351.1 - 1.2e-06 28.8 19.9 4.5 8.3 0.0 10.6 12 1 1 13 13 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO70351.1 - 0.00076 19.3 0.9 13 6.1 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDO70351.1 - 0.014 15.2 2.3 7.7 6.5 0.4 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDO70351.1 - 0.18 12.5 14.2 23 6.0 0.6 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat BTAD PF03704.17 CDO70351.1 - 1.2 9.6 7.5 1.8 9.0 0.0 4.5 4 0 0 4 4 4 0 Bacterial transcriptional activator domain Wzy_C_2 PF11846.8 CDO70351.1 - 1.8 8.5 5.4 8.7 6.2 0.1 4.0 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal Thioredoxin PF00085.20 CDO70352.1 - 1.7e-48 162.8 0.0 4.7e-24 84.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 CDO70352.1 - 3.5e-05 24.1 0.0 0.11 12.8 0.0 3.0 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CDO70352.1 - 0.00014 22.2 0.5 0.015 15.8 0.1 3.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 CDO70352.1 - 0.0085 16.1 0.0 0.58 10.2 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain OST3_OST6 PF04756.13 CDO70352.1 - 0.025 14.0 0.0 5.7 6.2 0.0 2.7 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CDO70352.1 - 0.026 14.7 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 CDO70352.1 - 0.089 12.7 0.1 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family SCO1-SenC PF02630.14 CDO70353.1 - 1.4e-47 161.0 0.0 2.7e-47 160.1 0.0 1.5 1 0 0 1 1 1 1 SCO1/SenC CGI-121 PF08617.10 CDO70353.1 - 9.5e-25 87.6 0.1 7.6e-24 84.7 0.1 2.0 1 1 1 2 2 2 1 Kinase binding protein CGI-121 AhpC-TSA PF00578.21 CDO70353.1 - 2.2e-05 24.4 0.0 6.8e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CDO70353.1 - 0.015 15.6 0.0 0.028 14.8 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Gram_pos_anchor PF00746.21 CDO70353.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif NDUF_B7 PF05676.13 CDO70354.1 - 3.9e-21 74.6 7.8 1.4e-19 69.6 7.8 2.0 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) VWA_2 PF13519.6 CDO70355.1 - 1e-23 84.0 1.3 1.4e-23 83.5 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 CDO70355.1 - 7e-12 44.4 14.1 0.00024 20.8 0.1 3.6 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 CDO70355.1 - 4.6e-05 23.3 0.1 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 Ssl1-like DUF4698 PF15769.5 CDO70355.1 - 1.5 7.8 7.4 1.9 7.4 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) DUF4719 PF15843.5 CDO70355.1 - 1.8 8.7 4.9 1.5 8.9 3.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4719) HNF-1_N PF04814.13 CDO70355.1 - 7.5 7.1 9.5 14 6.2 9.5 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Actin PF00022.19 CDO70356.1 - 1e-141 472.2 0.0 6.4e-141 469.7 0.0 1.8 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 CDO70356.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CBM_1 PF00734.18 CDO70358.1 - 1.8e-15 56.5 10.3 4.6e-15 55.3 10.3 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Amidohydro_2 PF04909.14 CDO70359.1 - 0.031 14.0 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase Nop14 PF04147.12 CDO70360.1 - 0.26 9.5 11.3 0.28 9.4 11.3 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 CDO70360.1 - 4.7 6.3 5.8 5.5 6.1 5.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 CDO70360.1 - 9.9 5.4 14.4 13 5.0 14.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4939 PF16297.5 CDO70361.1 - 8.3e-07 28.9 0.0 9.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) HSBP1 PF06825.12 CDO70362.1 - 0.00059 19.6 1.1 1.6 8.6 0.2 2.9 3 0 0 3 3 3 2 Heat shock factor binding protein 1 DUF5446 PF17522.2 CDO70362.1 - 0.0025 17.9 1.4 0.0097 16.1 1.1 2.0 1 1 1 2 2 2 1 Family of unknown function (DUF5446) ABC_tran_CTD PF16326.5 CDO70362.1 - 0.0025 18.0 1.3 0.062 13.6 0.2 2.6 2 0 0 2 2 2 1 ABC transporter C-terminal domain AKNA PF12443.8 CDO70362.1 - 0.044 14.4 0.5 0.65 10.7 0.0 2.4 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF16 PF01519.16 CDO70362.1 - 0.072 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 PIN_8 PF18476.1 CDO70362.1 - 0.078 12.8 0.8 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 PIN like domain IL4 PF00727.18 CDO70362.1 - 0.1 12.9 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Interleukin 4 DUF3450 PF11932.8 CDO70362.1 - 0.14 11.4 2.5 0.22 10.8 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) XhlA PF10779.9 CDO70362.1 - 1.1 9.5 4.2 5.7 7.2 0.1 2.6 3 0 0 3 3 3 0 Haemolysin XhlA F-box-like PF12937.7 CDO70364.1 - 0.0018 18.1 0.0 0.0081 16.0 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO70364.1 - 0.0091 15.9 0.6 0.027 14.4 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 CDO70364.1 - 0.047 13.6 0.1 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 F-box DIMCO_N PF16844.5 CDO70364.1 - 0.17 12.2 0.5 0.4 11.0 0.5 1.6 1 1 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor, N-terminal DUF155 PF02582.14 CDO70365.1 - 6.8e-43 146.8 0.0 1e-42 146.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DEAD PF00270.29 CDO70366.1 - 1.2e-37 129.4 0.2 4.1e-18 65.8 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO70366.1 - 7.9e-27 93.8 0.0 1.1e-25 90.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO70366.1 - 0.0017 18.4 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C2H2 PF00096.26 CDO70371.1 - 2.5e-05 24.5 7.3 0.005 17.2 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO70371.1 - 0.0012 19.5 7.1 0.027 15.3 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 CDO70371.1 - 0.012 16.2 2.7 0.051 14.2 0.5 2.6 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 CDO70371.1 - 0.016 15.7 8.7 0.019 15.4 2.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 CDO70371.1 - 0.019 14.7 0.7 0.031 14.0 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CDO70371.1 - 4.4 7.7 5.3 28 5.1 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.22 CDO70372.1 - 1.9e-40 136.5 0.0 2.3e-19 69.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CDO70372.1 - 2.5e-09 37.2 2.0 7e-05 22.9 0.0 3.3 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain CCDC24 PF15669.5 CDO70372.1 - 0.022 14.6 2.5 0.056 13.3 2.5 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family PAM2 PF07145.15 CDO70372.1 - 0.075 12.8 5.2 0.04 13.6 1.4 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Nup35_RRM_2 PF14605.6 CDO70372.1 - 0.1 12.6 0.1 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 CDO70372.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MFS_1 PF07690.16 CDO70373.1 - 2.1e-18 66.4 23.4 2.1e-18 66.4 23.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 CDO70374.1 - 1.7e-11 44.0 0.0 6e-11 42.2 0.0 1.9 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CDO70374.1 - 8e-06 26.0 3.1 2.2e-05 24.6 3.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDO70374.1 - 5.9e-05 22.8 7.0 6.9e-05 22.6 4.4 2.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDO70374.1 - 0.0001 21.7 0.7 0.0002 20.7 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDO70374.1 - 0.00023 21.7 1.0 0.00044 20.8 1.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDO70374.1 - 0.00055 18.7 0.7 0.00082 18.2 0.7 1.3 1 1 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 CDO70374.1 - 0.0013 18.1 0.8 0.0025 17.1 0.8 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 CDO70374.1 - 0.01 15.2 0.5 0.25 10.6 0.1 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 CDO70374.1 - 0.026 13.8 2.4 0.044 13.0 2.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDO70374.1 - 0.068 12.2 5.2 0.11 11.6 5.2 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 CDO70374.1 - 0.071 12.4 1.0 0.37 10.0 0.7 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 CDO70374.1 - 0.1 11.4 2.5 0.14 11.0 2.5 1.1 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.16 CDO70374.1 - 0.12 12.0 1.1 0.21 11.2 1.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CDO70374.1 - 0.19 11.6 2.2 0.33 10.8 2.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CDO70374.1 - 0.23 10.5 3.2 0.32 10.0 3.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 CDO70374.1 - 0.82 9.7 2.7 11 6.0 1.4 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sterol_MT_C PF08498.10 CDO70375.1 - 2e-28 98.5 0.1 3.9e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 CDO70375.1 - 3.5e-17 62.6 0.0 5.6e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO70375.1 - 4.4e-17 62.5 0.0 7.9e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO70375.1 - 1.8e-15 57.4 0.0 3.4e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CDO70375.1 - 4e-14 52.6 0.0 5.5e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CDO70375.1 - 1.2e-10 41.5 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO70375.1 - 2.1e-10 41.2 0.0 5.9e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDO70375.1 - 1.4e-07 31.1 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CDO70375.1 - 0.00021 21.1 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 CDO70375.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 CDO70375.1 - 0.0011 18.1 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.12 CDO70375.1 - 0.0086 15.7 0.0 0.018 14.6 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 CDO70375.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.6 CDO70375.1 - 0.02 15.9 0.0 0.14 13.2 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_4 PF02390.17 CDO70375.1 - 0.029 13.8 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.18 CDO70375.1 - 0.053 13.2 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 CDO70375.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CDO70375.1 - 0.17 11.9 0.0 0.94 9.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.22 CDO70376.1 - 3.6e-07 29.3 0.0 6.1e-07 28.5 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 p450 PF00067.22 CDO70377.1 - 2.1e-42 145.5 0.0 2.6e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 CDO70377.1 - 1e-15 58.2 0.0 1.6e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CDO70378.1 - 1.1e-10 42.1 0.0 2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 CDO70378.1 - 1.1e-09 38.1 0.0 2.1e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.12 CDO70378.1 - 0.15 12.2 0.0 12 6.0 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Het-C PF07217.11 CDO70379.1 - 4.6e-190 632.9 0.1 2.5e-185 617.3 0.0 3.8 2 1 0 2 2 2 2 Heterokaryon incompatibility protein Het-C NTF2 PF02136.20 CDO70380.1 - 6.9e-29 100.9 0.1 1.1e-28 100.2 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 CDO70380.1 - 4e-10 39.4 0.0 6.8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDO70380.1 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif WD40 PF00400.32 CDO70381.1 - 1.3e-49 165.1 16.0 8.4e-10 39.1 0.1 11.8 12 0 0 12 12 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO70381.1 - 5.1e-28 97.2 0.0 0.0099 16.2 0.0 10.5 4 2 5 11 11 9 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CDO70381.1 - 2.1e-26 92.3 0.0 3.2e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CDO70381.1 - 1.7e-13 50.3 1.6 0.0044 16.0 0.0 6.5 5 2 2 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CDO70381.1 - 8.9e-07 28.5 0.0 0.37 10.1 0.0 4.6 5 1 1 6 6 6 2 WD40-like domain eIF2A PF08662.11 CDO70381.1 - 1e-05 25.5 1.6 0.44 10.4 0.1 5.0 4 2 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CDO70381.1 - 1.9e-05 24.4 0.2 5.3 7.1 0.0 6.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 CDO70381.1 - 0.00014 21.7 0.0 0.14 11.9 0.0 3.7 3 1 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 CDO70381.1 - 0.0007 18.4 0.2 2.5 6.7 0.1 3.5 2 2 0 2 2 2 2 Nucleoporin Nup120/160 ELYS-bb PF16687.5 CDO70381.1 - 0.0024 16.6 0.0 0.031 12.9 0.0 2.5 3 0 0 3 3 3 1 beta-propeller of ELYS nucleoporin DUF1513 PF07433.11 CDO70381.1 - 0.0083 15.2 0.2 3.5 6.6 0.0 3.6 4 1 0 4 4 4 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 CDO70381.1 - 0.014 13.9 0.2 20 3.6 0.0 3.5 3 0 0 3 3 3 0 Cytochrome D1 heme domain RRM_1 PF00076.22 CDO70381.1 - 0.096 12.5 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 CDO70381.1 - 0.23 9.4 0.0 29 2.4 0.0 3.2 3 0 0 3 3 3 0 IKI3 family Sugar_tr PF00083.24 CDO70382.1 - 5.7e-103 345.2 16.6 6.6e-103 345.0 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO70382.1 - 9.7e-32 110.2 32.2 5.9e-23 81.4 13.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CHASE8 PF17152.4 CDO70382.1 - 0.0075 16.5 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 Periplasmic sensor domain MFS_5 PF05631.14 CDO70382.1 - 0.038 12.9 6.2 0.031 13.2 1.3 2.3 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM DUF2838 PF10998.8 CDO70382.1 - 0.1 12.8 5.0 0.16 12.2 0.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2838) Wzy_C_2 PF11846.8 CDO70382.1 - 0.34 10.8 0.0 0.34 10.8 0.0 2.5 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal DUF3792 PF12670.7 CDO70382.1 - 9.3 6.5 20.9 3.7 7.7 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) Alpha-L-AF_C PF06964.12 CDO70383.1 - 2.6e-28 99.2 0.0 3.8e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 CDO70383.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase family 44 zf-H2C2_5 PF13909.6 CDO70384.1 - 0.32 10.8 1.3 23 4.8 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 CDO70384.1 - 1.8 9.2 9.8 0.22 12.0 0.5 2.9 2 1 0 2 2 2 0 Zinc finger, C2H2 type Rad52_Rad22 PF04098.15 CDO70385.1 - 8.6e-57 191.4 0.0 1.5e-56 190.6 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein TFIIA PF03153.13 CDO70385.1 - 0.075 13.0 5.3 0.13 12.3 5.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRIMA1 PF16101.5 CDO70387.1 - 0.098 12.7 1.0 18 5.4 0.1 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 zf-H2C2_2 PF13465.6 CDO70388.1 - 0.00027 21.2 5.6 0.019 15.4 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 CDO70388.1 - 0.0042 17.5 11.7 0.1 13.1 1.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO70388.1 - 5.5 8.1 9.9 3.5 8.7 1.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger AA_permease_2 PF13520.6 CDO70392.1 - 3.8e-42 144.6 40.6 3.4e-36 125.0 20.2 2.5 1 1 1 2 2 2 2 Amino acid permease COX7B PF05392.11 CDO70392.1 - 0.22 11.2 1.1 0.48 10.1 0.2 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB Pkinase PF00069.25 CDO70393.1 - 9.9e-46 156.2 0.0 1.4e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70393.1 - 6e-44 150.3 0.0 1.2e-43 149.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CDO70393.1 - 1.1e-07 31.6 1.0 2.4e-07 30.5 1.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.14 CDO70393.1 - 0.0061 15.9 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.29 CDO70393.1 - 0.012 15.5 2.2 0.023 14.6 2.2 1.5 1 0 0 1 1 1 0 PHD-finger APH PF01636.23 CDO70393.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO70393.1 - 0.047 12.5 0.0 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase C1_2 PF03107.16 CDO70393.1 - 0.049 13.9 0.9 0.098 13.0 0.9 1.5 1 0 0 1 1 1 0 C1 domain Haspin_kinase PF12330.8 CDO70393.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Arginosuc_synth PF00764.19 CDO70394.1 - 6.4e-155 516.2 0.0 7.7e-155 516.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CDO70394.1 - 0.00014 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CDO70394.1 - 0.016 14.0 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase Noc2 PF03715.13 CDO70395.1 - 3.9e-118 394.0 0.0 8e-118 393.0 0.0 1.5 1 0 0 1 1 1 1 Noc2p family TNRC6-PABC_bdg PF16608.5 CDO70396.1 - 0.056 13.1 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 TNRC6-PABC binding domain Ald_Xan_dh_C2 PF02738.18 CDO70396.1 - 0.16 10.4 0.0 0.19 10.1 0.0 1.0 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase HSP70 PF00012.20 CDO70397.1 - 0.062 11.5 0.0 0.24 9.5 0.0 1.8 2 0 0 2 2 2 0 Hsp70 protein ALO PF04030.14 CDO70398.1 - 3.8e-77 259.6 0.0 5.5e-77 259.1 0.0 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CDO70398.1 - 1.1e-26 93.2 0.1 4.5e-26 91.2 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain UQ_con PF00179.26 CDO70399.1 - 4.6e-39 133.3 0.0 3.3e-28 98.1 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UQ_con PF00179.26 CDO70401.1 - 7.5e-45 152.0 0.0 8.7e-45 151.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDO70401.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UPF0261 PF06792.11 CDO70402.1 - 1.2e-152 508.6 0.0 1.4e-152 508.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PEP_hydrolase PF09370.10 CDO70403.1 - 5.1e-89 298.0 1.4 5.8e-89 297.8 1.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like Lactococcin_972 PF09683.10 CDO70403.1 - 0.094 13.3 0.3 0.17 12.4 0.3 1.4 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) Got1 PF04178.12 CDO70404.1 - 3e-33 114.6 11.2 4e-33 114.2 11.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2157 PF09925.9 CDO70404.1 - 0.0011 18.7 10.1 0.0099 15.7 3.8 2.2 1 1 1 2 2 2 2 Predicted membrane protein (DUF2157) DUF2070 PF09843.9 CDO70404.1 - 0.0037 15.6 3.5 0.0044 15.4 3.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) AgrB PF04647.15 CDO70404.1 - 0.036 13.4 4.3 0.048 13.0 4.3 1.1 1 0 0 1 1 1 0 Accessory gene regulator B DUF2207 PF09972.9 CDO70404.1 - 0.65 8.7 4.9 1.8 7.2 4.9 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Nup192 PF11894.8 CDO70405.1 - 2.8e-249 830.4 0.0 3.7e-249 830.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Acetyltransf_1 PF00583.25 CDO70406.1 - 2.7e-16 59.8 0.0 3.6e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDO70406.1 - 4.9e-10 39.4 0.0 6.4e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDO70406.1 - 5.6e-10 39.1 0.1 7.9e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CDO70406.1 - 1.2e-09 38.4 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CDO70406.1 - 2.1e-06 28.4 0.0 2.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDO70406.1 - 4.9e-06 26.6 0.1 6.9e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CDO70406.1 - 4.3e-05 23.2 0.0 6.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CDO70406.1 - 7.6e-05 22.9 0.0 9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDO70406.1 - 0.014 15.5 0.1 0.024 14.7 0.1 1.4 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 CDO70406.1 - 0.077 12.7 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ NMT PF01233.19 CDO70406.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain HSP70 PF00012.20 CDO70407.1 - 9.5e-264 876.1 7.2 1.1e-263 875.9 7.2 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDO70407.1 - 1.5e-19 70.0 0.5 8.4e-19 67.5 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 CDO70407.1 - 0.0036 16.4 0.7 0.12 11.3 0.5 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain 4HBT PF03061.22 CDO70407.1 - 0.0073 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily FGGY_C PF02782.16 CDO70407.1 - 0.029 14.1 0.0 0.09 12.5 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FIVAR PF07554.13 CDO70407.1 - 0.11 13.3 0.3 6 7.7 0.1 3.0 2 1 0 2 2 2 0 FIVAR domain Spectrin PF00435.21 CDO70407.1 - 0.16 12.5 7.3 6 7.4 0.1 3.4 3 0 0 3 3 3 0 Spectrin repeat DUF4290 PF14123.6 CDO70409.1 - 0.18 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4290) RAP1 PF07218.11 CDO70411.1 - 1.1 7.4 8.7 1.4 7.1 8.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MT-A70 PF05063.14 CDO70412.1 - 3.9e-38 131.1 0.0 8.2e-38 130.0 0.0 1.5 1 1 0 1 1 1 1 MT-A70 N6-adenineMlase PF10237.9 CDO70412.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase tRNA-synt_1 PF00133.22 CDO70413.1 - 1.5e-37 129.2 0.0 9.1e-28 96.9 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) SNF2_N PF00176.23 CDO70413.1 - 1.3e-35 122.8 0.0 1.9e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDO70413.1 - 3.9e-20 72.3 0.0 2.3e-18 66.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain tRNA-synt_1g PF09334.11 CDO70413.1 - 1.5e-15 56.8 0.0 4.9e-08 32.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CDO70413.1 - 1.3e-13 51.2 2.0 1.3e-13 51.2 0.2 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CDO70413.1 - 1e-07 31.6 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain ERCC3_RAD25_C PF16203.5 CDO70413.1 - 0.00012 21.4 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase MFS_1 PF07690.16 CDO70414.1 - 9.4e-12 44.5 43.0 1.2e-11 44.2 40.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Oxysterol_BP PF01237.18 CDO70415.1 - 2e-59 201.3 1.3 1.2e-50 172.4 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein SurE PF01975.17 CDO70417.1 - 5.4e-22 78.5 1.0 7.7e-22 78.0 1.0 1.2 1 0 0 1 1 1 1 Survival protein SurE SurE PF01975.17 CDO70418.1 - 2.9e-23 82.7 1.2 4.4e-23 82.1 1.2 1.3 1 0 0 1 1 1 1 Survival protein SurE KRTAP7 PF15034.6 CDO70418.1 - 0.019 15.9 0.2 0.04 14.9 0.2 1.5 1 0 0 1 1 1 0 KRTAP type 7 family Kelch_4 PF13418.6 CDO70419.1 - 4.1e-39 132.3 12.0 1.3e-06 28.3 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 CDO70419.1 - 4.5e-37 125.4 9.4 8e-08 31.7 0.2 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 CDO70419.1 - 8.1e-33 111.9 8.1 1.2e-08 34.7 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CDO70419.1 - 4.2e-31 106.6 13.7 2.9e-07 30.6 0.1 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 CDO70419.1 - 4.6e-26 90.2 10.0 6.1e-06 26.3 0.0 5.9 5 2 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CDO70419.1 - 6.8e-24 82.9 14.9 9.3e-07 28.6 0.1 5.9 6 1 0 6 6 6 5 Kelch motif Fer4_14 PF13394.6 CDO70419.1 - 0.026 14.6 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain FAM27 PF15832.5 CDO70419.1 - 0.045 14.3 4.9 0.11 13.0 4.9 1.7 1 0 0 1 1 1 0 FAM27 D and E protein family Hamartin PF04388.12 CDO70419.1 - 1.1 7.8 2.4 1.5 7.4 2.4 1.1 1 0 0 1 1 1 0 Hamartin protein SMP PF04927.12 CDO70420.1 - 0.00091 19.7 27.0 0.049 14.1 1.3 5.5 4 2 0 4 4 4 3 Seed maturation protein Ifi-6-16 PF06140.13 CDO70420.1 - 0.12 12.3 3.5 20 5.2 0.0 3.3 3 0 0 3 3 3 0 Interferon-induced 6-16 family HMG_box PF00505.19 CDO70421.1 - 3.2e-24 85.1 1.0 5e-24 84.5 1.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO70421.1 - 2.8e-18 66.3 1.4 5e-18 65.5 1.4 1.4 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 CDO70421.1 - 0.00075 19.4 0.0 0.0015 18.4 0.0 1.5 1 1 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.13 CDO70421.1 - 0.0016 19.0 0.6 0.0022 18.6 0.5 1.3 1 1 0 1 1 1 1 YABBY protein HMG_box_5 PF14887.6 CDO70421.1 - 0.023 14.6 2.0 0.023 14.6 2.0 1.8 1 1 1 2 2 2 0 HMG (high mobility group) box 5 Peptidase_C65 PF10275.9 CDO70422.1 - 1.7e-69 234.0 0.0 2.1e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 CDO70422.1 - 0.00017 22.1 0.0 0.0099 16.4 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease Mst1_SARAH PF11629.8 CDO70423.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Aminotran_4 PF01063.19 CDO70424.1 - 5.3e-19 69.0 0.0 7.7e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV SurE PF01975.17 CDO70425.1 - 1.9e-31 109.4 0.2 2.9e-31 108.8 0.2 1.3 1 0 0 1 1 1 1 Survival protein SurE DUF1412 PF07203.11 CDO70425.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) SMP PF04927.12 CDO70427.1 - 0.00026 21.4 9.4 0.011 16.1 0.1 4.4 4 0 0 4 4 4 2 Seed maturation protein Peptidase_M28 PF04389.17 CDO70428.1 - 0.034 13.8 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Amino_oxidase PF01593.24 CDO70430.1 - 2.5e-57 195.1 0.8 5.1e-57 194.1 0.8 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDO70430.1 - 8.2e-09 35.6 0.2 8.2e-09 35.6 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDO70430.1 - 0.00028 20.2 0.2 0.0045 16.3 0.2 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDO70430.1 - 0.0013 18.2 1.1 0.0017 17.8 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDO70430.1 - 0.0031 16.8 0.8 0.005 16.1 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CDO70430.1 - 0.0041 17.7 1.2 0.036 14.6 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDO70430.1 - 0.0044 16.6 4.9 0.0063 16.1 2.3 2.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDO70430.1 - 0.037 13.1 1.4 0.06 12.4 1.4 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 CDO70430.1 - 0.071 12.4 0.4 0.12 11.6 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 CDO70430.1 - 0.089 12.9 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 CDO70430.1 - 0.22 10.8 0.5 0.44 9.7 0.4 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amidohydro_2 PF04909.14 CDO70431.1 - 4.7e-20 72.5 0.0 9.3e-20 71.6 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase TatD_DNase PF01026.21 CDO70431.1 - 0.006 16.0 0.0 0.013 14.8 0.0 1.5 2 0 0 2 2 2 1 TatD related DNase BolA PF01722.18 CDO70433.1 - 1.3e-12 47.8 0.2 4.3e-06 26.9 0.0 2.5 2 1 0 2 2 2 2 BolA-like protein Pkinase PF00069.25 CDO70434.1 - 9.1e-57 192.4 0.0 1.7e-56 191.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70434.1 - 2.8e-30 105.5 0.0 2.2e-19 69.8 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CDO70434.1 - 0.00011 22.2 0.0 0.00041 20.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDO70434.1 - 0.00019 20.9 0.0 0.14 11.5 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 CDO70434.1 - 0.00072 19.0 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDO70434.1 - 0.025 13.4 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CDO70434.1 - 0.076 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CDO70434.1 - 0.11 12.2 0.0 16 5.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SMP PF04927.12 CDO70435.1 - 3.8e-08 33.7 29.3 0.014 15.9 0.1 6.6 5 3 0 5 5 5 5 Seed maturation protein DUF2384 PF09722.10 CDO70435.1 - 0.00011 22.1 0.2 9.4 6.4 0.0 4.1 4 0 0 4 4 4 3 Protein of unknown function (DUF2384) NUMOD3 PF07460.11 CDO70435.1 - 0.038 14.2 0.0 96 3.3 0.0 4.1 4 0 0 4 4 4 0 NUMOD3 motif (2 copies) RrnaAD PF00398.20 CDO70436.1 - 2.9e-62 210.1 0.1 3.9e-62 209.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CDO70436.1 - 1.8e-07 31.8 0.0 4.2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO70436.1 - 2.4e-05 24.9 0.0 5.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDO70436.1 - 0.00013 21.8 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 CDO70436.1 - 0.00038 20.3 0.0 0.0008 19.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CDO70436.1 - 0.00042 19.9 0.1 0.0013 18.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CDO70436.1 - 0.00056 20.6 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CDO70436.1 - 0.0018 17.6 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 CDO70436.1 - 0.0033 16.8 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 CDO70436.1 - 0.0092 15.8 0.0 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 CDO70436.1 - 0.021 13.9 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.17 CDO70436.1 - 0.024 14.3 0.1 0.078 12.6 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cons_hypoth95 PF03602.15 CDO70436.1 - 0.041 13.5 0.1 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 UPF0146 PF03686.13 CDO70436.1 - 0.041 13.7 0.2 9.4 6.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Ubie_methyltran PF01209.18 CDO70436.1 - 0.042 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 CDO70436.1 - 0.051 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Met_10 PF02475.16 CDO70436.1 - 0.085 12.6 0.1 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Met-10+ like-protein SPX PF03105.19 CDO70437.1 - 0.85 9.5 12.4 0.12 12.3 7.9 1.7 2 0 0 2 2 2 0 SPX domain Pan3_PK PF18101.1 CDO70439.1 - 3.3e-65 218.2 0.0 6.2e-65 217.3 0.0 1.5 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CDO70439.1 - 0.00013 21.4 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TFA2_Winged_2 PF18121.1 CDO70440.1 - 1.2e-21 76.2 0.1 3.5e-21 74.7 0.1 1.9 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 CDO70440.1 - 3.2e-14 53.0 0.8 1.9e-13 50.5 0.2 2.3 2 0 0 2 2 2 1 TFIIE beta subunit core domain HSP20 PF00011.21 CDO70441.1 - 6.4e-24 84.1 0.0 8.2e-24 83.7 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDO70441.1 - 7.6e-11 41.4 0.0 1.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 CDO70441.1 - 0.012 16.7 0.0 0.015 16.3 0.0 1.2 1 0 0 1 1 1 0 CS domain Amidohydro_3 PF07969.11 CDO70442.1 - 5.8e-45 154.6 0.1 6.4e-45 154.5 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CDO70442.1 - 7e-08 32.2 0.0 6.1e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDO70443.1 - 5.8e-24 85.4 0.3 7.7e-24 85.0 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family PPR_2 PF13041.6 CDO70444.1 - 2.9e-09 37.0 0.0 0.042 14.0 0.0 4.9 5 1 0 5 5 5 2 PPR repeat family PPR_long PF17177.4 CDO70444.1 - 5e-05 22.8 0.1 0.42 9.9 0.0 3.1 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CDO70444.1 - 8.2e-05 22.6 2.5 15 6.1 0.3 6.2 5 1 0 5 5 5 2 PPR repeat Striatin PF08232.12 CDO70444.1 - 0.023 15.3 0.0 0.07 13.7 0.0 1.8 1 0 0 1 1 1 0 Striatin family PPR_3 PF13812.6 CDO70444.1 - 0.029 14.4 0.0 50 4.1 0.0 3.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 CDO70444.1 - 0.18 11.6 0.0 7.8 6.3 0.0 3.1 3 0 0 3 3 3 0 PPR repeat DUF3729 PF12526.8 CDO70444.1 - 5.5 8.6 10.5 4.2 9.0 3.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Bromo_TP PF07524.13 CDO70445.1 - 1.3e-07 31.5 0.4 1.1e-06 28.6 0.1 2.1 2 0 0 2 2 2 1 Bromodomain associated Bromo_TP_like PF17027.5 CDO70445.1 - 0.23 11.6 0.0 0.31 11.2 0.0 1.2 1 0 0 1 1 1 0 Histone-fold protein CTP_transf_like PF01467.26 CDO70446.1 - 7.5e-15 55.4 0.0 1.2e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like SRAP PF02586.14 CDO70447.1 - 2.7e-64 216.7 0.0 3.4e-63 213.1 0.0 2.1 1 1 0 1 1 1 1 SOS response associated peptidase (SRAP) CUE PF02845.16 CDO70448.1 - 7.2e-08 32.0 0.0 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain DSPc PF00782.20 CDO70449.1 - 4.1e-26 91.4 0.0 6.7e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 CDO70449.1 - 5.6e-05 23.6 0.0 0.00028 21.4 0.0 2.2 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 CDO70449.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDO70449.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family LSM PF01423.22 CDO70450.1 - 8.8e-19 67.0 0.0 1.1e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CDO70450.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain PheRS_DBD2 PF18554.1 CDO70450.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 PheRS DNA binding domain 2 HEAT PF02985.22 CDO70451.1 - 1.4e-18 65.3 14.4 0.0014 18.7 0.1 10.8 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.6 CDO70451.1 - 1.3e-13 51.1 21.7 3e-08 34.0 0.0 9.0 9 2 2 11 11 11 2 HEAT-like repeat HEAT_2 PF13646.6 CDO70451.1 - 1.3e-12 47.9 12.0 0.0033 17.8 0.4 7.6 4 2 2 7 7 7 4 HEAT repeats Arm PF00514.23 CDO70451.1 - 7.5e-10 38.5 10.7 0.0018 18.3 0.1 7.3 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 CDO70451.1 - 3.8e-09 36.3 0.1 1.5e-07 31.2 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.12 CDO70451.1 - 0.00021 21.1 1.7 6.8 6.4 0.0 4.3 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis DRIM PF07539.12 CDO70451.1 - 0.00025 19.5 1.2 8.1 4.6 0.0 4.9 4 1 1 5 5 5 1 Down-regulated in metastasis Adaptin_N PF01602.20 CDO70451.1 - 0.00073 18.2 3.5 0.42 9.1 1.5 3.2 2 2 0 2 2 2 2 Adaptin N terminal region MMS19_C PF12460.8 CDO70451.1 - 0.011 14.9 3.9 0.29 10.2 0.1 3.6 3 2 0 3 3 3 0 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 CDO70451.1 - 0.015 15.4 2.9 4.7 7.2 0.0 4.1 4 2 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.10 CDO70451.1 - 0.029 14.2 0.1 0.53 10.0 0.0 2.9 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) FPL PF09758.9 CDO70451.1 - 0.073 13.1 0.0 0.31 11.0 0.0 2.1 1 0 0 1 1 1 0 Uncharacterised conserved protein DUF3385 PF11865.8 CDO70451.1 - 0.11 12.3 3.6 8.6 6.2 0.1 4.5 4 2 1 5 5 5 0 Domain of unknown function (DUF3385) MU117 PF15474.6 CDO70454.1 - 1.2e-13 51.7 10.0 1.5e-13 51.4 10.0 1.1 1 0 0 1 1 1 1 Meiotically up-regulated gene family MIF4G PF02854.19 CDO70455.1 - 5.2e-48 163.5 1.2 9.7e-30 103.8 0.0 3.6 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 CDO70455.1 - 2.6e-29 102.7 4.9 2.6e-29 102.7 4.9 3.4 2 1 0 2 2 2 1 Up-frameshift suppressor 2 AATF-Che1 PF13339.6 CDO70455.1 - 0.39 11.4 3.0 1 10.0 0.6 2.9 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor DUF4360 PF14273.6 CDO70456.1 - 0.015 15.2 0.3 0.025 14.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4360) Spc7 PF08317.11 CDO70456.1 - 0.97 8.3 6.3 0.23 10.3 3.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.12 CDO70456.1 - 2.8 8.4 7.9 9.7 6.6 5.9 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Retrotran_gag_2 PF14223.6 CDO70457.1 - 5.3e-17 61.8 0.0 1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CDO70457.1 - 3.9e-08 32.8 0.4 8.6e-08 31.7 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) DUF4687 PF15747.5 CDO70457.1 - 0.024 15.1 1.4 0.055 14.0 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) CPSF100_C PF13299.6 CDO70457.1 - 0.72 10.0 5.2 0.2 11.8 1.3 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal HSBP1 PF06825.12 CDO70459.1 - 0.00059 19.6 1.1 1.6 8.6 0.2 2.9 3 0 0 3 3 3 2 Heat shock factor binding protein 1 DUF5446 PF17522.2 CDO70459.1 - 0.0024 18.0 1.4 0.0097 16.1 1.1 2.1 1 1 1 2 2 2 1 Family of unknown function (DUF5446) ABC_tran_CTD PF16326.5 CDO70459.1 - 0.0025 18.0 1.3 0.062 13.6 0.2 2.6 2 0 0 2 2 2 1 ABC transporter C-terminal domain AKNA PF12443.8 CDO70459.1 - 0.043 14.5 0.5 0.65 10.7 0.0 2.4 1 1 1 2 2 2 0 AT-hook-containing transcription factor PIN_8 PF18476.1 CDO70459.1 - 0.061 13.2 0.7 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 PIN like domain DUF16 PF01519.16 CDO70459.1 - 0.071 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 IL4 PF00727.18 CDO70459.1 - 0.099 12.9 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Interleukin 4 DUF3450 PF11932.8 CDO70459.1 - 0.13 11.5 2.5 0.22 10.8 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) XhlA PF10779.9 CDO70459.1 - 1.3 9.3 4.7 5.7 7.2 0.1 2.7 3 0 0 3 3 3 0 Haemolysin XhlA Pkinase PF00069.25 CDO70461.1 - 2.4e-64 217.3 0.0 2.9e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70461.1 - 2.1e-27 96.0 0.0 3.2e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO70461.1 - 4.6e-05 22.9 0.0 6.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDO70461.1 - 0.00024 20.5 0.1 0.00041 19.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDO70461.1 - 0.00069 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CDO70461.1 - 0.0026 17.7 0.3 0.26 11.2 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO70461.1 - 0.018 14.0 0.3 0.039 12.9 0.3 1.4 1 1 0 1 1 1 0 Haspin like kinase domain HET PF06985.11 CDO70462.1 - 3.1e-10 40.6 3.4 2.2e-07 31.3 0.1 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Acetyltransf_1 PF00583.25 CDO70463.1 - 7.6e-18 64.9 0.0 8.8e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO70463.1 - 2.2e-08 34.4 0.0 3.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDO70463.1 - 3.8e-07 30.1 0.0 5.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDO70463.1 - 0.0023 18.0 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 CDO70463.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 CDO70463.1 - 0.067 13.9 0.0 0.088 13.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAC PF01849.18 CDO70464.1 - 2.3e-23 81.9 0.1 4.4e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 NAC domain WD40 PF00400.32 CDO70465.1 - 7.1e-22 77.3 17.1 0.0011 19.7 2.5 9.3 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO70465.1 - 4.4e-15 55.7 0.2 1.1e-06 28.8 0.0 6.0 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain GspH PF12019.8 CDO70465.1 - 0.003 18.0 0.1 3.9 7.9 0.0 3.0 3 0 0 3 3 3 2 Type II transport protein GspH CPSF_A PF03178.15 CDO70465.1 - 0.0033 16.8 0.0 2.6 7.3 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region RAB3GAP2_N PF14655.6 CDO70465.1 - 0.015 14.6 0.0 0.26 10.5 0.0 2.7 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 CDO70465.1 - 0.12 11.3 0.3 2.3 7.1 0.0 2.9 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mad3_BUB1_I PF08311.12 CDO70466.1 - 6.2e-36 123.1 0.1 8.9e-36 122.6 0.1 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 ECH_1 PF00378.20 CDO70466.1 - 0.056 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Pro-kuma_activ PF09286.11 CDO70467.1 - 5.2e-39 133.8 0.1 2.2e-38 131.7 0.2 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO70467.1 - 1e-06 28.2 2.1 1.6e-05 24.4 0.1 2.4 1 1 1 2 2 2 2 Subtilase family Pro-kuma_activ PF09286.11 CDO70468.1 - 6.3e-32 110.8 0.1 3.8e-31 108.3 0.1 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Glyco_hydro_47 PF01532.20 CDO70470.1 - 2.4e-105 353.1 0.0 3.2e-105 352.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 zf-CSL PF05207.13 CDO70471.1 - 0.015 15.0 0.7 2 8.2 0.1 2.9 2 0 0 2 2 2 0 CSL zinc finger FtsL PF04999.13 CDO70471.1 - 0.21 11.6 2.5 0.21 11.6 0.9 1.7 2 0 0 2 2 2 0 Cell division protein FtsL Ribophorin_II PF05817.14 CDO70472.1 - 3.7e-34 118.3 0.0 4.4e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF3778 PF12620.8 CDO70472.1 - 0.14 11.8 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) BRCA-2_OB3 PF09104.10 CDO70474.1 - 0.14 11.8 0.1 1.1 8.9 0.0 2.2 1 1 1 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 PCI PF01399.27 CDO70475.1 - 9.2e-22 77.5 0.0 2.8e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.11 CDO70475.1 - 2.5e-12 47.0 10.2 5.5e-08 33.1 0.1 3.6 4 0 0 4 4 4 2 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 CDO70475.1 - 0.016 15.3 3.5 0.14 12.3 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat OKR_DC_1_C PF03711.15 CDO70475.1 - 0.13 12.6 0.2 3.1 8.1 0.1 2.6 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain TPR_12 PF13424.6 CDO70475.1 - 3.1 8.1 9.7 13 6.1 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat WW PF00397.26 CDO70476.1 - 0.00022 21.2 3.0 0.0035 17.4 0.1 2.6 2 0 0 2 2 2 1 WW domain Cation_efflux PF01545.21 CDO70476.1 - 0.0039 17.0 0.3 0.062 13.0 0.3 2.2 1 1 0 1 1 1 1 Cation efflux family PgaD PF13994.6 CDO70476.1 - 0.076 13.1 0.1 0.076 13.1 0.1 2.0 2 1 0 2 2 2 0 PgaD-like protein Peptidase_C14 PF00656.22 CDO70477.1 - 1.3e-36 126.8 0.0 1.5e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain SPA PF08616.10 CDO70479.1 - 1.8e-32 111.6 0.0 3e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 CDO70479.1 - 4.7e-19 69.2 0.0 1.7e-16 60.9 0.0 2.3 1 1 1 2 2 2 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 CDO70479.1 - 3.2e-05 22.8 0.0 0.00097 17.9 0.0 2.8 4 0 0 4 4 4 1 Transport protein Avl9 Cas_Csy2 PF09614.10 CDO70480.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) Coatomer_WDAD PF04053.14 CDO70481.1 - 1.8e-139 465.6 0.0 5.4e-139 464.1 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 CDO70481.1 - 1.4e-113 379.7 0.0 2e-113 379.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CDO70481.1 - 4.6e-41 138.0 12.3 6e-08 33.2 0.2 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO70481.1 - 8.7e-09 35.6 0.3 0.00066 19.9 0.0 5.3 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 CDO70481.1 - 0.0049 17.6 2.8 2.9 8.9 0.3 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Nup160 PF11715.8 CDO70481.1 - 0.022 13.4 3.0 1.3 7.5 0.0 3.2 1 1 2 3 3 3 0 Nucleoporin Nup120/160 TPR_2 PF07719.17 CDO70481.1 - 0.074 13.2 0.4 23 5.4 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.20 CDO70481.1 - 0.082 12.8 0.2 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS XPG_I PF00867.18 CDO70482.1 - 2.6e-13 50.1 0.0 4.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CDO70482.1 - 0.0084 16.7 0.0 0.021 15.4 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold LIM PF00412.22 CDO70483.1 - 5.5e-15 55.3 15.1 8.6e-11 41.9 8.0 3.1 3 0 0 3 3 3 2 LIM domain zf_UBZ PF18439.1 CDO70483.1 - 1.1 9.0 9.7 8 6.1 0.1 3.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger p450 PF00067.22 CDO70484.1 - 6.5e-50 170.2 0.0 1.4e-49 169.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 TetR_C_28 PF17937.1 CDO70484.1 - 0.061 13.8 2.1 35 4.9 0.1 3.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain COesterase PF00135.28 CDO70485.1 - 1e-83 282.0 2.3 1.3e-82 278.3 2.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDO70485.1 - 7e-10 39.1 0.4 4.1e-09 36.6 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDO70485.1 - 0.00034 20.1 0.3 0.00063 19.3 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2235 PF09994.9 CDO70485.1 - 0.14 11.5 0.1 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) FoP_duplication PF13865.6 CDO70486.1 - 1.4e-06 28.7 0.3 2.8e-06 27.8 0.3 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 CDO70486.1 - 0.00024 20.8 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HlyIII PF03006.20 CDO70488.1 - 3e-45 154.7 12.2 3.9e-45 154.3 12.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related NADH-u_ox-rdase PF10785.9 CDO70488.1 - 0.27 11.9 2.6 1.6 9.5 0.3 2.4 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit p450 PF00067.22 CDO70489.1 - 2.1e-22 79.5 0.0 5.4e-14 51.8 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 RVT_1 PF00078.27 CDO70490.1 - 2.8e-09 36.8 0.0 7.3e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDO70490.1 - 0.0019 17.8 0.8 0.0057 16.2 0.1 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Cofilin_ADF PF00241.20 CDO70491.1 - 2e-28 98.6 0.3 2.2e-28 98.5 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Sec20 PF03908.13 CDO70492.1 - 9.2e-16 57.5 1.5 9.2e-16 57.5 1.5 2.3 3 1 1 4 4 4 1 Sec20 AAA_13 PF13166.6 CDO70492.1 - 0.035 12.8 4.5 0.046 12.4 4.5 1.3 1 0 0 1 1 1 0 AAA domain Baculo_11_kDa PF06143.11 CDO70492.1 - 0.054 13.1 0.1 0.16 11.5 0.1 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family HBS1_N PF08938.10 CDO70492.1 - 0.13 12.6 0.5 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 HBS1 N-terminus Neugrin PF06413.11 CDO70493.1 - 9.2e-12 45.4 2.3 1.6e-11 44.7 2.3 1.4 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 CDO70493.1 - 2.3e-06 27.8 10.7 5.1e-06 26.7 10.7 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 MarR_2 PF12802.7 CDO70493.1 - 0.0043 16.9 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 MarR family HTH_Tnp_ISL3 PF13542.6 CDO70493.1 - 0.017 14.5 1.2 2.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 BTB PF00651.31 CDO70494.1 - 8.5e-06 26.0 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain FYVE PF01363.21 CDO70495.1 - 3.3e-08 33.6 5.3 7.9e-08 32.3 5.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CDO70495.1 - 0.00011 22.4 3.2 0.00011 22.4 3.2 2.3 3 0 0 3 3 3 1 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 CDO70495.1 - 0.00027 20.7 8.8 0.0025 17.6 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Armet PF10208.9 CDO70495.1 - 0.0032 17.4 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding DUF4518 PF15008.6 CDO70495.1 - 0.011 14.9 3.0 0.92 8.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) SAP PF02037.27 CDO70495.1 - 0.024 14.4 0.2 0.17 11.7 0.0 2.4 2 1 0 2 2 2 0 SAP domain Rho_N PF07498.12 CDO70495.1 - 0.039 13.9 0.2 0.082 12.9 0.2 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain DUF2254 PF10011.9 CDO70495.1 - 0.26 10.1 0.4 1.7 7.4 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) C1_1 PF00130.22 CDO70495.1 - 0.54 10.2 8.1 0.16 11.9 4.5 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.6 CDO70495.1 - 2.6 8.2 8.1 1.4 9.0 1.9 2.9 2 1 1 3 3 3 0 RING-type zinc-finger Zn-ribbon_8 PF09723.10 CDO70495.1 - 7.9 6.7 9.2 1.3 9.2 2.3 2.6 1 1 1 2 2 2 0 Zinc ribbon domain Chromo PF00385.24 CDO70496.1 - 1.4e-08 34.5 0.5 2.4e-08 33.8 0.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 CDO70496.1 - 0.00015 21.6 0.1 0.00031 20.6 0.1 1.5 1 0 0 1 1 1 1 PHD-finger ABC_tran_CTD PF16326.5 CDO70496.1 - 0.037 14.3 0.1 0.34 11.2 0.0 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain RHH_5 PF07878.11 CDO70496.1 - 0.071 13.0 0.1 0.46 10.4 0.0 2.3 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Apolipoprotein PF01442.18 CDO70496.1 - 0.085 12.7 4.1 0.15 11.9 4.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MbeD_MobD PF04899.12 CDO70496.1 - 0.11 12.6 0.1 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 MbeD/MobD like FliT PF05400.13 CDO70496.1 - 0.14 13.0 1.6 3.4 8.5 0.1 2.6 1 1 1 2 2 2 0 Flagellar protein FliT Spc7 PF08317.11 CDO70496.1 - 0.22 10.3 1.0 0.32 9.8 1.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Cytochrom_NNT PF03264.14 CDO70496.1 - 0.25 11.0 0.0 0.48 10.1 0.0 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region BLOC1_2 PF10046.9 CDO70496.1 - 0.32 11.3 1.2 0.78 10.1 0.5 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FMO-like PF00743.19 CDO70497.1 - 1.3e-44 152.6 0.0 3.7e-33 114.7 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CDO70497.1 - 8.2e-14 51.6 0.0 3.7e-09 36.3 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDO70497.1 - 1.6e-11 44.0 0.0 5.3e-09 35.7 0.0 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDO70497.1 - 1.7e-06 27.4 0.0 0.00091 18.5 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CDO70497.1 - 5.3e-06 26.5 0.5 0.02 14.9 0.0 3.6 3 1 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 CDO70497.1 - 6.2e-06 26.0 0.1 2.7 7.5 0.0 4.2 4 0 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDO70497.1 - 1.7e-05 25.3 0.4 0.0033 18.0 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO70497.1 - 6.4e-05 23.1 0.0 0.004 17.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CDO70497.1 - 0.058 12.6 0.1 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 CDO70497.1 - 0.06 12.6 0.2 2.4 7.4 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Tannase PF07519.11 CDO70498.1 - 3.3e-74 250.5 0.2 3.3e-73 247.2 0.2 2.1 1 1 0 1 1 1 1 Tannase and feruloyl esterase p450 PF00067.22 CDO70499.1 - 1.3e-43 149.5 0.0 2.6e-24 85.8 0.0 3.1 3 0 0 3 3 3 3 Cytochrome P450 p450 PF00067.22 CDO70501.1 - 1.5e-47 162.4 1.5 3.9e-22 78.7 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 FMO-like PF00743.19 CDO70501.1 - 7.4e-39 133.6 0.0 4.3e-28 98.0 0.0 2.7 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CDO70501.1 - 1.5e-13 50.7 0.1 1.7e-10 40.6 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDO70501.1 - 9e-08 31.6 0.0 5.3e-06 25.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CDO70501.1 - 4.5e-07 29.4 0.0 2.5e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO70501.1 - 0.0001 22.3 1.2 0.79 9.7 0.0 4.7 4 1 0 5 5 5 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CDO70501.1 - 0.00017 21.8 0.1 0.0014 18.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CDO70501.1 - 0.052 12.8 0.0 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 CDO70501.1 - 0.28 10.4 1.2 11 5.2 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain RSN1_7TM PF02714.15 CDO70502.1 - 2.2e-82 276.4 25.5 3.7e-82 275.7 25.5 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CDO70502.1 - 1.2e-37 129.0 5.0 6.4e-37 126.7 5.0 2.3 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CDO70502.1 - 6.2e-32 111.2 0.0 1.1e-30 107.2 0.0 2.2 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CDO70502.1 - 6.7e-13 48.6 1.0 1.5e-12 47.5 0.2 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter Anoctamin PF04547.12 CDO70502.1 - 0.0056 15.6 0.4 0.0056 15.6 0.4 3.0 3 0 0 3 3 3 2 Calcium-activated chloride channel TarH PF02203.15 CDO70502.1 - 0.27 11.1 1.7 11 5.9 0.1 2.6 2 0 0 2 2 2 0 Tar ligand binding domain homologue F-box-like PF12937.7 CDO70503.1 - 1e-08 34.9 0.1 3.3e-08 33.3 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO70503.1 - 0.00094 19.0 0.1 0.0039 17.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO70504.1 - 5.4e-08 32.6 0.2 8.7e-08 31.9 0.2 1.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 CDO70504.1 - 0.0024 17.7 0.8 0.005 16.7 0.8 1.6 1 1 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 CDO70504.1 - 0.037 14.0 0.0 0.083 12.9 0.0 1.7 1 1 0 1 1 1 0 F-box-like domain TPR_9 PF13371.6 CDO70504.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat ADH_N PF08240.12 CDO70505.1 - 8.3e-28 96.4 1.0 1.5e-27 95.6 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO70505.1 - 8.6e-28 96.9 2.2 1.5e-27 96.2 2.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO70505.1 - 2.5e-05 25.4 0.3 4.3e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 CDO70505.1 - 0.06 12.8 1.8 0.12 11.8 1.2 2.0 1 1 1 2 2 2 0 short chain dehydrogenase p450 PF00067.22 CDO70506.1 - 1.4e-53 182.3 0.0 1.7e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Spindle_Spc25 PF08234.12 CDO70507.1 - 1.5e-09 37.9 0.1 4.4e-09 36.4 0.1 1.9 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 CENP-K PF11802.8 CDO70507.1 - 0.0045 16.6 6.6 0.0056 16.3 6.6 1.1 1 0 0 1 1 1 1 Centromere-associated protein K DUF812 PF05667.11 CDO70507.1 - 0.033 13.1 13.1 0.041 12.8 13.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TPP_enzyme_M_2 PF16582.5 CDO70507.1 - 0.062 13.0 0.9 0.11 12.2 0.9 1.3 1 0 0 1 1 1 0 Middle domain of thiamine pyrophosphate MecA_N PF05223.11 CDO70507.1 - 0.19 12.0 3.3 0.29 11.4 3.3 1.3 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain Spc7 PF08317.11 CDO70507.1 - 0.26 10.2 15.3 0.48 9.3 15.2 1.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.6 CDO70507.1 - 0.38 11.2 17.4 0.21 12.0 15.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 CDO70507.1 - 0.47 11.0 14.2 0.26 11.8 12.3 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 CDO70507.1 - 1.2 8.5 12.7 1.5 8.1 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CDO70507.1 - 1.3 9.1 5.5 3.9 7.5 5.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 CDO70507.1 - 2.2 7.4 5.6 2.9 7.1 5.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 CDO70507.1 - 2.5 7.3 11.9 4.4 6.5 11.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Spc24 PF08286.11 CDO70507.1 - 3 8.2 9.4 1.6e+02 2.6 9.4 2.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 AATase PF07247.12 CDO70508.1 - 1.2e-19 70.3 0.0 7.2e-10 38.0 0.0 3.0 3 0 0 3 3 3 3 Alcohol acetyltransferase Condensation PF00668.20 CDO70508.1 - 0.00014 20.7 0.0 0.0011 17.7 0.0 2.2 3 0 0 3 3 3 1 Condensation domain WES_acyltransf PF03007.16 CDO70508.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain PAS_5 PF07310.13 CDO70508.1 - 0.018 14.8 0.1 0.34 10.7 0.1 2.3 2 0 0 2 2 2 0 PAS domain p450 PF00067.22 CDO70510.1 - 1.4e-12 47.2 0.0 1.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CDO70511.1 - 3e-30 105.4 0.0 5.9e-30 104.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF1770 PF08589.10 CDO70512.1 - 6.1e-07 30.3 0.5 6.1e-07 30.3 0.5 1.8 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) PIG-L PF02585.17 CDO70513.1 - 5.4e-13 49.7 0.0 7.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF3455 PF11937.8 CDO70514.1 - 1.7e-21 77.3 0.0 2.5e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) peroxidase PF00141.23 CDO70515.1 - 6.7e-30 104.5 0.0 1.1e-29 103.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 CDO70515.1 - 2e-29 101.4 1.4 5.2e-29 100.0 1.4 1.8 1 0 0 1 1 1 1 Fungal peroxidase extension region HET PF06985.11 CDO70517.1 - 1.3e-12 48.2 2.4 0.00011 22.6 0.0 4.5 2 2 2 4 4 4 4 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.13 CDO70519.1 - 8.8e-14 51.9 1.2 6.7e-08 32.6 0.8 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1295 PF06966.12 CDO70520.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) F-box-like PF12937.7 CDO70521.1 - 7.6e-09 35.3 0.3 3e-08 33.4 0.3 2.1 1 0 0 1 1 1 1 F-box-like ParBc_2 PF08857.11 CDO70521.1 - 0.014 15.5 0.1 0.024 14.7 0.1 1.3 1 0 0 1 1 1 0 Putative ParB-like nuclease EzrA PF06160.12 CDO70521.1 - 0.028 12.6 0.0 0.038 12.2 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Laminin_II PF06009.12 CDO70521.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Laminin Domain II F-box PF00646.33 CDO70521.1 - 6 6.9 8.6 2.4 8.1 1.7 3.4 2 1 0 2 2 2 0 F-box domain p450 PF00067.22 CDO70522.1 - 9.3e-52 176.3 0.0 3.3e-50 171.2 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 SWIRM PF04433.17 CDO70524.1 - 8.1e-33 112.6 0.0 4.1e-32 110.4 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 CDO70524.1 - 1.9e-12 47.1 0.0 3.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDO70524.1 - 9.1e-10 38.7 0.0 1.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 CDO70524.1 - 3.3e-08 33.2 2.6 6.2e-08 32.3 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Glyco_hydro_61 PF03443.14 CDO70526.1 - 7e-35 120.8 0.0 8.3e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 CDO70527.1 - 1e-09 38.6 0.0 1.2e-09 38.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.25 CDO70528.1 - 1.9e-64 217.6 0.0 2.8e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70528.1 - 4.8e-32 111.3 0.0 7.7e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO70528.1 - 0.0008 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Syntaxin-6_N PF09177.11 CDO70529.1 - 1.1e-25 90.1 5.6 5.3e-25 87.9 0.6 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal PspA_IM30 PF04012.12 CDO70529.1 - 0.0028 17.2 6.8 0.0037 16.9 0.7 2.6 3 0 0 3 3 3 1 PspA/IM30 family JAKMIP_CC3 PF16034.5 CDO70529.1 - 0.0035 17.3 0.4 0.008 16.2 0.4 1.6 1 1 0 1 1 1 1 JAKMIP CC3 domain DUF3584 PF12128.8 CDO70529.1 - 0.0058 14.2 2.8 0.0098 13.5 2.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) SNARE PF05739.19 CDO70529.1 - 0.01 15.8 1.2 0.012 15.6 0.1 1.7 2 0 0 2 2 1 0 SNARE domain Use1 PF09753.9 CDO70529.1 - 0.013 15.2 2.0 0.025 14.3 2.0 1.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 Spc7 PF08317.11 CDO70529.1 - 0.02 13.8 7.2 0.24 10.3 0.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein CorA PF01544.18 CDO70529.1 - 0.027 13.8 2.8 0.33 10.2 0.2 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Spectrin PF00435.21 CDO70529.1 - 0.033 14.7 4.5 0.064 13.8 0.1 2.5 2 2 0 2 2 2 0 Spectrin repeat DUF1664 PF07889.12 CDO70529.1 - 0.065 13.3 1.7 6.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5446 PF17522.2 CDO70529.1 - 0.086 13.0 4.6 0.32 11.2 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5446) DUF948 PF06103.11 CDO70529.1 - 0.1 12.9 2.6 1.3 9.3 0.1 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 CDO70529.1 - 0.11 12.7 1.8 12 6.1 0.1 2.7 2 1 1 3 3 3 0 Haemolysin XhlA FlaC_arch PF05377.11 CDO70529.1 - 0.17 12.3 4.4 11 6.5 0.1 3.8 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Laminin_I PF06008.14 CDO70529.1 - 0.19 11.4 8.2 2 8.0 1.9 2.2 2 0 0 2 2 2 0 Laminin Domain I HMMR_N PF15905.5 CDO70529.1 - 0.9 8.9 6.3 1.8 8.0 1.1 2.2 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Jnk-SapK_ap_N PF09744.9 CDO70529.1 - 1.3 9.3 9.4 0.32 11.2 1.3 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 CDO70529.1 - 1.7 9.2 8.7 1.8 9.1 1.3 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4140 PF13600.6 CDO70529.1 - 2 8.9 6.9 0.25 11.8 0.3 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.12 CDO70529.1 - 4.1 7.5 11.9 8.6 6.4 0.6 2.8 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 CDO70529.1 - 6.1 6.1 10.8 4.2 6.6 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) zf-C3HC4_3 PF13920.6 CDO70530.1 - 5.6e-11 42.1 5.1 4.4e-09 36.1 1.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO70530.1 - 0.0003 20.6 1.8 0.0011 18.8 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDO70530.1 - 0.00068 19.4 4.4 0.00068 19.4 4.4 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CDO70530.1 - 0.0014 18.9 5.6 0.0043 17.4 1.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CDO70530.1 - 0.016 15.1 2.2 0.18 11.8 0.5 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDO70530.1 - 0.85 9.7 6.0 11 6.2 0.9 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Ribosomal_L27A PF00828.19 CDO70531.1 - 4.5e-22 79.1 0.0 6.9e-22 78.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_pol_L_2 PF13656.6 CDO70532.1 - 1.1e-26 92.4 0.0 1.4e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CDO70532.1 - 2.2e-12 46.2 0.0 3.4e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.11 CDO70532.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Rio2, N-terminal RVT_1 PF00078.27 CDO70533.1 - 3.2e-22 79.1 0.0 1.5e-21 77.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO70533.1 - 2.7e-08 33.6 0.0 6.3e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 CDO70533.1 - 3.6e-07 30.5 0.0 8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO70533.1 - 8.2e-06 26.5 0.1 0.00028 21.6 0.0 2.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CDO70533.1 - 0.041 13.4 0.1 0.12 11.8 0.1 1.9 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family zf-CCHC_6 PF15288.6 CDO70533.1 - 0.093 12.6 2.1 0.3 10.9 1.9 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDO70533.1 - 0.37 10.5 2.9 0.9 9.3 2.9 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger HIP1_clath_bdg PF16515.5 CDO70533.1 - 2.8 8.6 8.6 0.48 11.1 3.4 2.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 THOC7 PF05615.13 CDO70533.1 - 3 8.1 5.2 0.64 10.3 1.3 1.8 2 0 0 2 2 2 0 Tho complex subunit 7 DUF3328 PF11807.8 CDO70535.1 - 4.5e-12 46.2 0.8 5.8e-12 45.9 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.9 CDO70536.1 - 2.4e-08 34.5 0.0 3.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.8 CDO70537.1 - 1e-12 48.4 0.3 1e-12 48.4 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) DUF1917 PF08939.10 CDO70538.1 - 2.3e-22 80.2 0.0 2.3e-22 80.2 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) DUF3852 PF12963.7 CDO70542.1 - 0.016 15.6 1.7 0.017 15.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) p450 PF00067.22 CDO70543.1 - 1.1e-32 113.4 0.4 5.9e-17 61.6 0.0 3.9 3 1 0 3 3 3 3 Cytochrome P450 TMEM141 PF15110.6 CDO70543.1 - 0.073 13.7 0.0 0.23 12.1 0.0 1.8 2 0 0 2 2 2 0 TMEM141 protein family MotB_plug PF13677.6 CDO70543.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB Plavaka PF18759.1 CDO70545.1 - 4.3e-125 417.2 0.0 5.7e-125 416.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase p450 PF00067.22 CDO70546.1 - 2.7e-59 201.2 0.0 2.9e-58 197.8 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 DUF1796 PF08795.10 CDO70546.1 - 0.079 12.9 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) Internalin_N PF12354.8 CDO70547.1 - 0.18 11.9 3.1 0.23 11.6 0.1 2.7 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal MFS_1 PF07690.16 CDO70548.1 - 1.2e-07 31.0 25.2 4.2e-07 29.2 22.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_CII PF05269.11 CDO70548.1 - 0.15 12.3 0.0 6 7.1 0.0 2.3 1 1 1 2 2 2 0 Bacteriophage CII protein MFS_1 PF07690.16 CDO70549.1 - 7.2e-25 87.7 36.7 9.5e-25 87.3 36.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Importin_rep_2 PF18786.1 CDO70549.1 - 0.24 11.3 0.2 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Importin 13 repeat ELYS PF13934.6 CDO70550.1 - 7.5e-45 153.6 0.6 1.2e-44 152.9 0.6 1.3 1 0 0 1 1 1 1 Nuclear pore complex assembly HMG_box PF00505.19 CDO70551.1 - 0.059 13.8 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box p450 PF00067.22 CDO70552.1 - 8.4e-48 163.2 0.0 1.6e-38 132.6 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Ribosomal_S5_C PF03719.15 CDO70553.1 - 1.7e-17 62.6 0.1 5.2e-17 61.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CDO70553.1 - 9.5e-17 60.7 0.4 2.9e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain PITH PF06201.13 CDO70554.1 - 2.1e-16 60.5 0.0 2.7e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain Pkinase PF00069.25 CDO70555.1 - 2.1e-47 161.7 0.0 3e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70555.1 - 1e-28 100.4 0.0 1.4e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO70555.1 - 3.5e-05 23.3 0.0 0.0033 16.8 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.11 CDO70555.1 - 0.00036 19.6 1.8 0.00053 19.1 0.1 1.8 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.23 CDO70555.1 - 0.018 15.0 0.1 0.082 12.8 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family Asp PF00026.23 CDO70556.1 - 5.6e-39 134.4 0.3 1.4e-38 133.1 0.3 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO70556.1 - 2e-05 24.9 0.6 0.00025 21.3 0.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDO70556.1 - 0.15 11.8 0.1 3 7.6 0.0 2.7 3 1 0 3 3 3 0 Xylanase inhibitor C-terminal ATP-synt_10 PF05176.14 CDO70557.1 - 7.2e-64 215.5 0.0 8.7e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein TPT PF03151.16 CDO70559.1 - 1.1e-24 87.3 17.5 1.3e-24 87.1 17.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CDO70559.1 - 0.0024 18.0 34.2 0.019 15.2 9.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family LSM PF01423.22 CDO70562.1 - 3.3e-10 39.5 0.1 4.6e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Glyco_hydro_28 PF00295.17 CDO70563.1 - 1.9e-48 165.2 13.7 2.7e-48 164.7 13.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RmlD_sub_bind PF04321.17 CDO70566.1 - 1.1e-39 136.3 0.0 1.7e-31 109.4 0.0 2.0 1 1 1 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 CDO70566.1 - 9.2e-15 54.7 0.0 7.6e-07 28.8 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CDO70566.1 - 0.021 14.0 0.2 0.24 10.5 0.0 2.4 2 1 0 2 2 2 0 Male sterility protein DapB_N PF01113.20 CDO70566.1 - 0.04 14.0 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 CDO70566.1 - 0.044 13.2 0.9 2.3 7.5 0.0 2.5 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase RTC4 PF14474.6 CDO70567.1 - 1.4e-13 51.1 0.0 3.1e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain SDA1 PF05285.12 CDO70567.1 - 0.00061 19.3 8.0 0.022 14.2 2.6 2.3 2 0 0 2 2 2 2 SDA1 Transposase_21 PF02992.14 CDO70568.1 - 4.4e-15 55.5 0.0 2.3e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 NUDIX PF00293.28 CDO70571.1 - 2.6e-13 50.1 0.1 3.3e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Ldh_1_N PF00056.23 CDO70572.1 - 2e-46 157.6 0.1 3e-46 157.0 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CDO70572.1 - 5.5e-42 143.5 0.0 7.5e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CDO70572.1 - 7.1e-05 21.9 0.0 0.00016 20.8 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 CDO70572.1 - 0.0057 16.2 0.0 0.38 10.3 0.1 2.4 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase NAD_binding_10 PF13460.6 CDO70572.1 - 0.096 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 CDO70572.1 - 0.37 10.1 3.6 2.5 7.4 0.2 3.2 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DEAD PF00270.29 CDO70573.1 - 3.4e-43 147.5 0.0 1e-42 145.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO70573.1 - 4.5e-27 94.6 0.1 4.1e-26 91.5 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO70573.1 - 3.8e-05 23.7 0.1 0.0004 20.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CDO70573.1 - 0.011 15.1 5.1 0.37 10.1 0.0 2.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.6 CDO70573.1 - 0.13 12.4 1.5 0.29 11.3 0.0 2.3 2 0 0 2 2 2 0 Helicase C-terminal domain SAM_DrpA PF18255.1 CDO70573.1 - 0.16 12.2 0.0 0.5 10.7 0.0 1.9 2 0 0 2 2 2 0 DNA processing protein A sterile alpha motif domain PTPRCAP PF15713.5 CDO70573.1 - 7.2 6.9 16.0 13 6.0 16.0 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated VSG_B PF13206.6 CDO70573.1 - 8 5.6 12.5 12 5.0 12.5 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain GalP_UDP_transf PF01087.22 CDO70574.1 - 1.3e-65 221.3 0.0 2.4e-65 220.4 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 CDO70574.1 - 4.3e-50 169.7 0.0 8.7e-50 168.7 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 CDO70574.1 - 0.011 14.6 0.3 0.98 8.2 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4921) HIT PF01230.23 CDO70574.1 - 0.22 12.3 0.9 3 8.6 0.0 2.8 3 0 0 3 3 3 0 HIT domain DcpS_C PF11969.8 CDO70574.1 - 0.6 10.6 2.0 3.6 8.1 2.0 2.2 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding SDA1 PF05285.12 CDO70575.1 - 6.1e-95 318.6 26.8 6.1e-95 318.6 26.8 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 CDO70575.1 - 1.3e-25 89.4 0.0 7.7e-25 87.0 0.0 2.3 2 0 0 2 2 2 1 NUC130/3NT domain RhoGAP PF00620.27 CDO70575.1 - 0.084 12.7 0.6 6 6.7 0.0 2.6 2 0 0 2 2 2 0 RhoGAP domain OATP PF03137.20 CDO70575.1 - 2.5 6.3 4.8 0.39 8.9 0.1 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4061 PF13270.6 CDO70576.1 - 0.15 12.4 7.1 0.32 11.3 7.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) DUF4538 PF15061.6 CDO70576.1 - 0.16 11.7 0.9 0.37 10.6 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Atg14 PF10186.9 CDO70576.1 - 4.5 6.3 11.7 5.7 5.9 11.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TIP120 PF08623.10 CDO70576.1 - 6.3 6.5 7.3 9.4 6.0 7.3 1.2 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) TMPIT PF07851.13 CDO70576.1 - 9.2 5.4 8.4 12 5.0 8.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein PGK PF00162.19 CDO70577.1 - 3.4e-148 493.6 0.1 4.9e-148 493.1 0.1 1.2 1 0 0 1 1 1 1 Phosphoglycerate kinase Sel1 PF08238.12 CDO70577.1 - 1.9e-50 168.2 24.1 5.1e-09 36.5 0.0 8.1 7 0 0 7 7 7 7 Sel1 repeat PITH PF06201.13 CDO70577.1 - 1.4e-30 106.6 0.2 2.4e-30 105.8 0.2 1.3 1 0 0 1 1 1 1 PITH domain JHD PF17811.1 CDO70577.1 - 1.2e-11 45.1 0.0 2.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 CDO70577.1 - 5.3e-07 30.1 0.6 4.1e-06 27.2 0.6 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CDO70577.1 - 0.0019 17.9 0.3 0.0071 16.1 0.3 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CDO70577.1 - 0.022 14.2 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein TPR_14 PF13428.6 CDO70577.1 - 0.072 13.9 6.0 1.6 9.8 0.8 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat CN_hydrolase PF00795.22 CDO70578.1 - 2e-55 188.0 0.0 2.7e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DnaJ_C PF01556.18 CDO70578.1 - 9.9e-39 132.8 0.2 1.6e-38 132.1 0.2 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDO70578.1 - 1.1e-21 76.7 1.0 2.2e-21 75.7 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDO70578.1 - 2.2e-16 60.0 17.2 3.8e-16 59.2 17.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CDO70578.1 - 8.1e-07 28.9 10.7 0.00014 21.7 1.4 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Ras PF00071.22 CDO70579.1 - 2.1e-52 177.0 0.0 2.4e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO70579.1 - 3.2e-21 75.8 0.0 4.4e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO70579.1 - 1.5e-06 27.8 0.0 3.5e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDO70579.1 - 0.00046 20.1 0.0 0.023 14.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 CDO70579.1 - 0.086 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PIG-X PF08320.12 CDO70580.1 - 3.8e-33 115.2 0.1 5.4e-33 114.7 0.1 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 6PF2K PF01591.18 CDO70581.1 - 3.7e-59 199.7 0.1 4.2e-31 108.0 0.0 2.0 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CDO70581.1 - 2.4e-21 76.3 0.0 5.5e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 CDO70581.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 CDO70581.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rsa3 PF14615.6 CDO70581.1 - 0.087 12.4 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Ribosome-assembly protein 3 AAA_17 PF13207.6 CDO70581.1 - 0.093 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PNK3P PF08645.11 CDO70582.1 - 1.7e-44 151.4 0.0 5.2e-44 149.8 0.0 1.8 2 1 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CDO70582.1 - 5.4e-14 52.6 0.0 2.7e-11 43.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain Hydrolase_6 PF13344.6 CDO70582.1 - 0.0012 18.9 0.1 0.031 14.4 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase KTI12 PF08433.10 CDO70582.1 - 0.0063 16.0 0.6 0.076 12.4 0.6 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CDO70582.1 - 0.024 13.9 0.0 0.57 9.4 0.0 2.5 2 1 1 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.23 CDO70582.1 - 0.041 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DAGK_cat PF00781.24 CDO70583.1 - 2.3e-17 62.8 0.0 3.6e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ADK PF00406.22 CDO70584.1 - 1e-45 155.5 0.1 2.1e-45 154.5 0.1 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDO70584.1 - 2.1e-33 115.6 0.4 4.2e-33 114.6 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDO70584.1 - 5.4e-08 33.4 0.0 8.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CDO70584.1 - 2.4e-07 30.6 1.0 0.0023 17.6 0.4 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 CDO70584.1 - 5.7e-05 23.3 0.1 0.00071 19.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain SPK PF04435.18 CDO70584.1 - 0.026 14.9 0.4 0.65 10.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF545) WD40 PF00400.32 CDO70585.1 - 0.014 16.3 2.4 0.16 12.9 0.2 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Fungal_trans PF04082.18 CDO70586.1 - 2.1e-09 36.8 1.4 5e-09 35.6 1.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Uricase PF01014.18 CDO70587.1 - 2e-17 63.7 0.1 2.4e-17 63.4 0.1 1.0 1 0 0 1 1 1 1 Uricase Aldo_ket_red PF00248.21 CDO70589.1 - 5.9e-42 143.9 0.0 9.1e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_1 PF00515.28 CDO70590.1 - 8.6e-21 72.8 2.5 2.3e-05 24.0 0.5 5.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 CDO70590.1 - 2.2e-16 58.6 12.5 0.0018 18.3 0.6 6.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CDO70590.1 - 2.5e-13 49.1 1.1 0.017 15.3 0.1 5.7 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CDO70590.1 - 9.5e-12 44.4 6.5 0.0015 18.2 0.6 5.5 5 1 1 6 6 6 3 TPR repeat TPR_16 PF13432.6 CDO70590.1 - 3.4e-11 43.6 11.8 2.4e-05 24.9 0.3 5.3 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDO70590.1 - 3.9e-11 42.8 21.1 0.0028 18.4 0.1 7.0 4 2 2 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDO70590.1 - 6.9e-11 42.5 9.3 8.5e-06 26.2 0.4 4.7 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 CDO70590.1 - 1.4e-10 40.8 10.4 0.052 13.9 0.0 6.0 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 CDO70590.1 - 7.2e-08 32.6 13.1 5.9e-05 23.3 0.6 4.8 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 CDO70590.1 - 1.2e-07 31.8 4.2 0.001 19.2 0.4 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.6 CDO70590.1 - 2.4e-05 24.6 5.7 0.65 10.4 0.1 4.9 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO70590.1 - 3.2e-05 23.6 8.1 2.4 8.4 0.1 5.9 5 1 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO70590.1 - 0.00018 21.6 2.5 0.023 14.9 0.5 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CDO70590.1 - 0.024 15.2 1.5 35 5.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 CDO70590.1 - 0.12 12.4 2.1 13 6.0 0.1 4.2 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CDO70590.1 - 0.25 11.3 15.5 1 9.3 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat F-box-like PF12937.7 CDO70591.1 - 2e-05 24.4 0.2 4.4e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO70591.1 - 0.0012 18.7 0.4 0.0053 16.6 0.4 2.1 1 1 0 1 1 1 1 F-box domain PRA1 PF03208.19 CDO70592.1 - 8.6e-21 74.1 7.1 2e-16 59.9 3.1 2.1 2 0 0 2 2 2 2 PRA1 family protein PAS PF00989.25 CDO70593.1 - 8.3e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 1 0 1 1 1 1 PAS fold PAS_3 PF08447.12 CDO70593.1 - 0.095 13.0 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold Zn_clus PF00172.18 CDO70594.1 - 2.8e-05 24.1 11.2 4.5e-05 23.5 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrmC_N PF17827.1 CDO70595.1 - 2.7e-05 24.7 0.2 5.6e-05 23.6 0.2 1.7 1 1 0 1 1 1 1 PrmC N-terminal domain WD40 PF00400.32 CDO70596.1 - 3.9e-40 135.1 22.6 1.5e-08 35.1 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO70596.1 - 4.8e-08 33.2 0.6 0.096 13.0 0.0 4.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDO70596.1 - 0.00037 19.3 3.0 0.17 10.5 0.2 3.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 CDO70596.1 - 0.0011 18.1 0.0 0.12 11.5 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1513) PD40 PF07676.12 CDO70596.1 - 0.0019 18.1 1.2 5.7 7.0 0.0 4.5 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 CDO70596.1 - 0.019 13.5 0.1 0.81 8.1 0.1 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF1416 PF07210.12 CDO70596.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) IU_nuc_hydro PF01156.19 CDO70597.1 - 4.4e-48 164.4 0.0 5.8e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MFS_1 PF07690.16 CDO70598.1 - 1.8e-09 37.0 31.3 1.8e-09 37.0 31.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily bZIP_1 PF00170.21 CDO70600.1 - 0.00014 21.8 3.9 0.00024 21.1 3.9 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDO70600.1 - 0.0011 18.9 3.3 0.0018 18.3 3.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper ZapB PF06005.12 CDO70600.1 - 0.025 15.0 0.5 0.039 14.4 0.5 1.2 1 0 0 1 1 1 0 Cell division protein ZapB Methyltransf_25 PF13649.6 CDO70605.1 - 1.9e-06 28.5 0.0 3.9e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO70605.1 - 3e-06 27.1 0.0 3.3e-06 27.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO70605.1 - 0.017 15.7 0.0 0.03 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CDO70605.1 - 0.027 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 CDO70606.1 - 6.1e-25 87.2 1.6 9.9e-25 86.5 1.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO70606.1 - 5.6e-16 58.7 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO70606.1 - 4.7e-09 37.4 0.0 7.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase VHS PF00790.19 CDO70608.1 - 1.2e-38 132.1 0.0 2.5e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 CDO70608.1 - 5.7e-14 52.2 2.5 1.3e-12 47.9 0.3 3.5 3 1 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 CDO70608.1 - 0.022 14.4 0.1 0.054 13.1 0.1 1.6 1 0 0 1 1 1 0 GGA N-GAT domain vATP-synt_E PF01991.18 CDO70609.1 - 1.8e-57 194.0 9.7 2.1e-57 193.8 9.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Fibrillarin_2 PF10113.9 CDO70609.1 - 0.075 11.7 0.2 0.09 11.4 0.2 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein DUF883 PF05957.13 CDO70609.1 - 7.2 7.3 10.4 0.83 10.3 4.0 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) PP-binding PF00550.25 CDO70610.1 - 0.016 15.6 0.0 0.039 14.3 0.0 1.6 2 0 0 2 2 2 0 Phosphopantetheine attachment site O-FucT PF10250.9 CDO70611.1 - 2.6e-08 33.9 0.0 3.3e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Pyridoxal_deC PF00282.19 CDO70613.1 - 3.3e-66 223.5 0.0 4.4e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CDO70613.1 - 1.7e-05 24.0 0.0 3.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Con-6 PF10346.9 CDO70614.1 - 2.7e-32 110.5 7.0 1.8e-16 59.8 1.4 2.3 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 CDO70614.1 - 0.0029 17.5 5.4 0.0044 16.9 0.8 2.0 1 1 1 2 2 2 1 SpoIIIAH-like protein ATP-synt_DE PF00401.20 CDO70614.1 - 0.024 14.9 4.4 0.031 14.6 2.1 2.1 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Glyco_transf_8C PF08437.10 CDO70614.1 - 0.28 11.3 0.6 18 5.5 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal MFS_1 PF07690.16 CDO70615.1 - 9.9e-22 77.3 74.7 1.5e-17 63.5 43.7 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Pil1 PF13805.6 CDO70616.1 - 3.4e-20 72.7 0.1 6.7e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3510 PF12022.8 CDO70616.1 - 0.065 13.6 0.4 0.14 12.5 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Pkinase PF00069.25 CDO70618.1 - 4.4e-40 137.7 0.0 1.3e-27 96.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70618.1 - 1.9e-20 73.3 0.0 2.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO70618.1 - 6.6e-05 21.9 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO70618.1 - 0.048 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDO70620.1 - 2.6e-42 145.0 0.0 3.1e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70620.1 - 1.2e-28 100.1 0.0 1.5e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO70620.1 - 0.00044 19.7 0.0 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDO70620.1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO70620.1 - 0.086 12.7 0.6 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family FA_desaturase PF00487.24 CDO70622.1 - 8.2e-15 55.3 27.3 3.9e-14 53.1 27.3 2.0 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 CDO70622.1 - 3.3e-07 30.6 0.0 5.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Alpha-L-AF_C PF06964.12 CDO70623.1 - 5.9e-28 98.1 0.0 2.8e-27 95.9 0.0 2.2 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_6 PF03422.15 CDO70623.1 - 0.0089 16.3 4.5 0.081 13.2 1.2 2.5 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) Lactamase_B_2 PF12706.7 CDO70624.1 - 6.2e-13 48.7 0.2 9.2e-12 44.9 0.2 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 CDO70624.1 - 1.3e-07 31.2 0.0 3.7e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 CDO70624.1 - 0.015 15.3 0.3 0.071 13.1 0.3 2.2 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF11 PF01345.18 CDO70625.1 - 0.013 15.8 0.0 0.043 14.1 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF11 Pkinase PF00069.25 CDO70626.1 - 2.2e-47 161.6 0.0 3e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70626.1 - 7e-27 94.3 0.0 9e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO70626.1 - 1.5e-05 25.0 0.2 0.00094 19.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDO70626.1 - 0.00029 20.2 0.0 0.00046 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDO70626.1 - 0.0036 16.6 0.0 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 CDO70626.1 - 0.0084 15.1 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 CDO70626.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 CDO70627.1 - 5e-51 173.6 0.0 8e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70627.1 - 8.1e-33 113.8 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO70627.1 - 4.7e-05 22.8 0.0 0.001 18.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF5575 PF17738.1 CDO70627.1 - 0.021 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5575) Kdo PF06293.14 CDO70627.1 - 0.079 12.3 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO70627.1 - 0.15 12.0 0.1 0.41 10.5 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CDO70627.1 - 0.19 11.3 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 BIR PF00653.21 CDO70628.1 - 1.4e-36 125.0 2.2 7.5e-18 65.0 0.6 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 CDO70628.1 - 0.00028 20.9 0.1 0.12 12.4 0.1 2.6 2 0 0 2 2 2 2 C3HC zinc finger-like AT_hook PF02178.19 CDO70628.1 - 0.0031 17.2 5.0 0.035 13.9 5.0 3.0 1 0 0 1 1 1 1 AT hook motif WAPL PF07814.13 CDO70629.1 - 1.1e-17 63.9 1.5 5.3e-17 61.7 1.5 2.0 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Importin_rep_4 PF18808.1 CDO70629.1 - 0.13 12.5 0.5 0.39 11.0 0.5 1.7 1 0 0 1 1 1 0 Importin repeat zf-C3HC4_3 PF13920.6 CDO70630.1 - 5.2e-05 23.0 4.4 9e-05 22.3 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CDO70630.1 - 0.00011 22.0 0.0 0.0003 20.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 CDO70630.1 - 0.00059 19.6 5.7 0.0012 18.7 5.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CDO70630.1 - 0.0026 17.6 5.7 0.0048 16.7 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO70630.1 - 0.0075 16.2 5.9 0.014 15.3 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDO70630.1 - 0.15 12.4 6.2 0.3 11.5 6.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CDO70630.1 - 1.1 9.1 6.3 2.3 8.1 6.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MRJP PF03022.16 CDO70631.1 - 4.8e-23 81.9 0.0 1.2e-22 80.6 0.0 1.6 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 CDO70631.1 - 0.0023 17.6 0.0 0.14 11.8 0.0 2.6 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region SGS PF05002.15 CDO70632.1 - 0.046 13.8 0.3 0.1 12.7 0.3 1.6 1 0 0 1 1 1 0 SGS domain Mlh1_C PF16413.5 CDO70633.1 - 2.2e-90 302.7 0.0 8.2e-90 300.8 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CDO70633.1 - 7.3e-29 99.9 0.1 1.5e-28 98.9 0.1 1.6 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Ribosomal_L4 PF00573.22 CDO70635.1 - 4.8e-40 137.3 1.5 7.9e-40 136.6 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CDO70635.1 - 3.3e-29 100.8 1.6 3.3e-29 100.8 1.6 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Pkinase PF00069.25 CDO70636.1 - 1.3e-52 178.8 0.0 8.6e-52 176.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70636.1 - 3.3e-30 105.2 0.0 3.4e-22 79.0 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 CDO70636.1 - 0.00017 21.6 1.3 0.033 14.1 0.0 2.9 2 2 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO70636.1 - 0.0017 17.2 0.1 0.0017 17.2 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CDO70636.1 - 0.078 12.3 0.2 20 4.3 0.0 3.0 3 0 0 3 3 3 0 Kinase-like Peptidase_S10 PF00450.22 CDO70637.1 - 2.3e-73 248.0 0.8 3.2e-73 247.6 0.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4783 PF16022.5 CDO70637.1 - 0.069 13.3 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) Coq4 PF05019.13 CDO70639.1 - 6.7e-99 329.7 0.0 8e-99 329.4 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Aminotran_1_2 PF00155.21 CDO70640.1 - 1.6e-29 103.2 0.0 2e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CDO70640.1 - 6.8e-10 38.3 0.0 1e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase UPF0014 PF03649.13 CDO70641.1 - 2.3e-67 226.9 13.2 2.8e-67 226.6 13.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Tubulin_2 PF13809.6 CDO70641.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Tubulin like GHMP_kinases_N PF00288.26 CDO70641.1 - 0.52 10.6 2.9 1 9.7 0.9 2.6 3 1 0 3 3 3 0 GHMP kinases N terminal domain BPD_transp_1 PF00528.22 CDO70641.1 - 2.2 8.0 13.6 0.66 9.7 8.9 2.2 1 1 1 2 2 2 0 Binding-protein-dependent transport system inner membrane component ABC2_membrane PF01061.24 CDO70642.1 - 4.2e-35 121.1 21.4 4.2e-35 121.1 21.4 1.6 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 CDO70642.1 - 2.4e-26 92.9 0.0 4.6e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter EGF_2 PF07974.13 CDO70642.1 - 2.1e-05 24.8 10.3 2.1e-05 24.8 10.3 4.0 4 0 0 4 4 3 2 EGF-like domain ABC2_membrane_3 PF12698.7 CDO70642.1 - 3.1e-05 23.3 25.7 3.1e-05 23.3 24.1 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 CDO70642.1 - 0.00074 19.4 0.3 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 CDO70642.1 - 0.005 16.8 0.0 0.0088 16.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 CDO70642.1 - 0.0074 16.0 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDO70642.1 - 0.019 14.9 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 CDO70642.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CDO70642.1 - 0.21 11.7 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 CDO70642.1 - 0.21 12.1 0.1 0.45 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Ala_racemase_N PF01168.20 CDO70643.1 - 4.7e-19 68.9 0.2 1.1e-17 64.5 0.2 2.6 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain NUC130_3NT PF08158.12 CDO70643.1 - 0.037 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 NUC130/3NT domain ADH_N_2 PF16884.5 CDO70644.1 - 5.7e-30 103.4 0.0 1e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 CDO70644.1 - 5.7e-17 61.9 0.0 9.6e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO70644.1 - 7.8e-10 39.9 0.0 1.7e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DFP PF04127.15 CDO70644.1 - 0.08 12.8 0.0 6.3 6.6 0.0 2.3 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Citrate_synt PF00285.21 CDO70645.1 - 6.9e-108 360.9 0.3 2e-97 326.5 0.0 2.0 2 0 0 2 2 2 2 Citrate synthase, C-terminal domain XPG_I PF00867.18 CDO70647.1 - 4.7e-27 94.2 0.0 1.5e-26 92.6 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDO70647.1 - 9.9e-22 77.3 0.0 2.5e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CDO70647.1 - 0.01 15.3 0.0 0.025 14.0 0.0 1.7 1 0 0 1 1 1 0 XPG domain containing 5_3_exonuc PF01367.20 CDO70647.1 - 0.039 14.6 0.4 0.31 11.7 0.0 2.7 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Methyltransf_25 PF13649.6 CDO70648.1 - 4.6e-15 56.1 0.0 1.6e-14 54.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO70648.1 - 2e-11 44.4 0.0 5.1e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO70648.1 - 2e-08 34.1 0.0 3.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO70648.1 - 4.5e-08 33.1 0.0 9.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDO70648.1 - 2.5e-07 30.3 0.0 4.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CDO70648.1 - 2.7e-06 26.8 0.0 4.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 CDO70648.1 - 1.9e-05 24.3 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CDO70648.1 - 5.9e-05 23.7 0.0 0.00014 22.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CDO70648.1 - 0.0032 17.4 0.0 0.037 13.9 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 CDO70648.1 - 0.0052 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 CDO70648.1 - 0.0068 15.8 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 CDO70648.1 - 0.044 13.2 0.0 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.9 CDO70648.1 - 0.058 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase TTSSLRR PF12468.8 CDO70648.1 - 0.49 10.7 5.6 0.23 11.7 0.3 2.6 2 1 0 2 2 2 0 Type III secretion system leucine rich repeat protein Peptidase_M24 PF00557.24 CDO70649.1 - 2.6e-18 66.5 0.1 3.7e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 ThrE PF06738.12 CDO70649.1 - 0.11 11.8 0.1 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 Putative threonine/serine exporter Coatomer_g_Cpla PF16381.5 CDO70649.1 - 0.14 12.3 0.9 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Coatomer subunit gamma-1 C-terminal appendage platform Aminotran_1_2 PF00155.21 CDO70650.1 - 7.4e-19 68.1 0.0 9.4e-09 34.9 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Aminotran_MocR PF12897.7 CDO70650.1 - 1.9e-09 36.8 0.0 2.6e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase RasGAP PF00616.19 CDO70651.1 - 2.4e-58 197.3 0.2 7e-58 195.8 0.0 1.9 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 CDO70651.1 - 1.3e-38 132.2 0.3 3.3e-38 130.9 0.3 1.8 1 0 0 1 1 1 1 RasGAP C-terminus IL2 PF00715.17 CDO70651.1 - 0.069 13.1 1.8 0.3 11.0 0.2 2.7 2 1 0 2 2 2 0 Interleukin 2 YabA PF06156.13 CDO70651.1 - 0.26 11.9 3.7 19 6.0 0.1 3.0 2 0 0 2 2 2 0 Initiation control protein YabA Telomerase_RBD PF12009.8 CDO70652.1 - 3.1e-43 147.1 0.4 1e-42 145.4 0.4 2.0 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CDO70652.1 - 3.6e-12 46.3 0.5 1.4e-06 28.0 0.0 3.4 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_2 PF07719.17 CDO70653.1 - 3.3e-09 36.2 7.7 5.8e-05 22.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDO70653.1 - 1e-06 29.0 0.7 0.0024 18.5 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO70653.1 - 5.4e-06 26.8 8.1 5.4e-06 26.8 0.8 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO70653.1 - 1.5e-05 25.1 1.3 2.2e-05 24.6 0.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CDO70653.1 - 4e-05 23.3 9.2 0.0069 16.2 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO70653.1 - 5.6e-05 22.9 0.5 2.1 8.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO70653.1 - 0.00015 21.4 0.4 0.37 10.5 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 CDO70653.1 - 0.00018 21.5 7.8 0.15 12.3 0.5 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDO70653.1 - 0.00032 21.2 1.6 2.1 9.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDO70653.1 - 0.0021 18.2 0.1 0.0051 16.9 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDO70653.1 - 0.011 16.3 0.3 0.21 12.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDO70653.1 - 0.013 15.8 1.9 0.18 12.1 0.3 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4919 PF16266.5 CDO70653.1 - 0.045 13.7 0.4 0.089 12.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_21 PF09976.9 CDO70653.1 - 0.18 11.5 7.0 1.4 8.5 2.2 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain COG2 PF06148.11 CDO70656.1 - 0.033 14.3 2.3 0.39 10.8 0.4 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Phosphonate-bd PF12974.7 CDO70657.1 - 0.00022 20.9 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 CDO70657.1 - 0.00059 19.8 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 CDO70657.1 - 0.026 13.9 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 NMT1-like family SBP_bac_3 PF00497.20 CDO70657.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Yip1 PF04893.17 CDO70659.1 - 9.5e-16 58.0 16.0 1.3e-15 57.6 16.0 1.2 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 CDO70659.1 - 0.98 9.2 12.7 1.4 8.6 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF4199 PF13858.6 CDO70659.1 - 6.5 7.1 11.8 0.066 13.6 3.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) AAA PF00004.29 CDO70660.1 - 2.4e-41 141.2 0.0 4.2e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDO70660.1 - 2.5e-10 40.0 1.0 4.8e-10 39.1 1.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CDO70660.1 - 8.7e-10 38.4 0.0 1.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CDO70660.1 - 5.4e-06 26.6 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CDO70660.1 - 3e-05 23.3 0.0 5.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CDO70660.1 - 4.7e-05 23.7 0.2 0.015 15.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDO70660.1 - 0.00029 21.3 0.2 0.0096 16.3 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CDO70660.1 - 0.00029 20.8 0.2 0.0017 18.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDO70660.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDO70660.1 - 0.0068 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CDO70660.1 - 0.0072 15.7 0.2 0.24 10.7 0.1 2.3 1 1 1 2 2 2 1 KaiC AAA_3 PF07726.11 CDO70660.1 - 0.0083 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDO70660.1 - 0.0096 16.5 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 CDO70660.1 - 0.011 15.3 0.3 0.054 13.1 0.0 2.3 3 0 0 3 3 2 0 Proteasomal ATPase OB N-terminal domain AAA_14 PF13173.6 CDO70660.1 - 0.014 15.4 0.1 0.059 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDO70660.1 - 0.023 14.9 0.2 0.098 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CDO70660.1 - 0.026 14.3 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 CDO70660.1 - 0.079 12.9 0.1 0.81 9.6 0.1 2.2 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 CDO70660.1 - 0.086 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 CDO70660.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CDO70660.1 - 0.1 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 CDO70660.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CDO70660.1 - 0.13 11.9 0.3 0.35 10.6 0.3 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CDO70660.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CDO70660.1 - 0.17 11.4 0.8 5.3 6.6 0.3 2.5 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 CDO70660.1 - 0.19 11.4 0.4 0.42 10.3 0.4 1.6 1 1 0 1 1 1 0 AAA domain PEP-utilisers_N PF05524.13 CDO70661.1 - 0.0044 17.2 1.8 0.014 15.6 1.0 2.2 1 1 0 1 1 1 1 PEP-utilising enzyme, N-terminal DP PF08781.10 CDO70661.1 - 0.0078 16.1 0.3 0.015 15.2 0.3 1.4 1 0 0 1 1 1 1 Transcription factor DP DUF5082 PF16888.5 CDO70661.1 - 0.039 14.2 3.9 14 6.0 1.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) FAM76 PF16046.5 CDO70661.1 - 0.045 13.1 0.1 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 FAM76 protein YabA PF06156.13 CDO70661.1 - 0.071 13.7 1.7 0.53 10.9 0.3 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Med9 PF07544.13 CDO70661.1 - 0.13 12.3 1.6 0.42 10.7 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.19 CDO70661.1 - 0.24 9.3 1.4 4 5.2 0.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SKA2 PF16740.5 CDO70661.1 - 0.31 10.9 6.3 0.18 11.6 1.9 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 FlaC_arch PF05377.11 CDO70661.1 - 0.36 11.3 3.1 0.6 10.5 0.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 CDO70661.1 - 1.1 9.3 4.8 0.86 9.6 1.0 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 CDO70661.1 - 6 7.6 10.1 26 5.5 3.0 2.8 2 1 0 2 2 2 0 SlyX PH PF00169.29 CDO70664.1 - 1.8e-07 31.6 0.1 3.4e-06 27.5 0.0 2.7 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 CDO70664.1 - 0.0011 19.4 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain BSP_II PF05432.11 CDO70664.1 - 0.03 14.0 1.8 0.078 12.7 1.8 1.6 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.6 CDO70664.1 - 0.97 9.9 4.1 5.2 7.5 4.1 2.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 CDO70664.1 - 3.5 7.4 7.8 13 5.5 7.8 2.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Plavaka PF18759.1 CDO70665.1 - 4.8e-125 417.1 0.0 6.3e-125 416.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase CCDC92 PF14916.6 CDO70666.1 - 0.026 14.3 0.1 0.049 13.4 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function FlxA PF14282.6 CDO70666.1 - 0.12 12.4 2.5 0.25 11.3 2.5 1.5 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.15 CDO70666.1 - 0.37 10.6 2.3 0.95 9.3 2.3 1.7 1 0 0 1 1 1 0 Septum formation initiator Abhydrolase_2 PF02230.16 CDO70668.1 - 1.7e-21 77.0 0.0 4.3e-20 72.5 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CDO70668.1 - 0.00023 21.8 1.6 0.0075 16.9 0.4 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CDO70668.1 - 0.00043 19.8 0.0 0.0016 18.0 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.14 CDO70668.1 - 0.046 13.0 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase DLH PF01738.18 CDO70668.1 - 0.11 12.1 0.0 0.22 11.0 0.0 1.6 2 1 0 2 2 2 0 Dienelactone hydrolase family SpoIIE PF07228.12 CDO70670.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CDO70670.1 - 0.0088 15.7 0.3 0.65 9.6 0.0 2.7 3 0 0 3 3 3 1 Protein phosphatase 2C MSG PF02349.15 CDO70670.1 - 0.1 12.8 0.5 0.16 12.2 0.5 1.2 1 0 0 1 1 1 0 Major surface glycoprotein CCDC53 PF10152.9 CDO70670.1 - 3.4 8.1 4.4 6.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF4451 PF14616.6 CDO70671.1 - 1.1e-25 90.2 0.0 2.3e-25 89.2 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) AAA PF00004.29 CDO70672.1 - 1.5e-54 184.0 0.0 1.1e-43 148.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CDO70672.1 - 3.5e-24 85.0 0.9 8.7e-24 83.7 0.9 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 CDO70672.1 - 3e-16 59.0 0.4 4e-10 39.3 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CDO70672.1 - 2.1e-10 41.2 2.5 0.0058 17.0 0.1 4.2 2 2 2 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 CDO70672.1 - 1.2e-06 28.8 2.8 0.23 11.7 0.1 4.9 4 2 0 4 4 3 2 AAA domain Bac_DnaA PF00308.18 CDO70672.1 - 5.1e-06 26.5 0.0 0.00088 19.2 0.0 2.6 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_14 PF13173.6 CDO70672.1 - 7.4e-06 26.0 0.0 0.088 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 CDO70672.1 - 3e-05 23.8 0.0 0.0047 16.7 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CDO70672.1 - 4.3e-05 23.5 0.1 0.19 11.7 0.0 3.7 3 1 0 3 3 3 1 NACHT domain TIP49 PF06068.13 CDO70672.1 - 6.6e-05 22.3 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 CDO70672.1 - 0.00013 21.7 0.0 0.57 9.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 CDO70672.1 - 0.00016 21.7 0.1 0.59 10.1 0.0 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDO70672.1 - 0.00024 21.7 0.0 0.17 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CDO70672.1 - 0.00033 20.0 0.0 0.73 9.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.27 CDO70672.1 - 0.00047 20.7 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 2 1 ABC transporter TsaE PF02367.17 CDO70672.1 - 0.00061 19.8 0.0 0.65 10.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 CDO70672.1 - 0.00062 19.7 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 CDO70672.1 - 0.0007 19.3 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 CDO70672.1 - 0.00077 19.6 0.0 0.024 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CDO70672.1 - 0.00088 19.4 0.0 0.038 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CDO70672.1 - 0.0015 18.9 0.0 0.96 9.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 CDO70672.1 - 0.0049 16.5 2.3 1 8.9 0.1 3.6 2 2 2 4 4 4 1 AAA domain DUF2075 PF09848.9 CDO70672.1 - 0.0057 15.9 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 CDO70672.1 - 0.011 15.2 0.2 0.65 9.3 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CDO70672.1 - 0.013 15.3 0.0 0.31 10.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CDO70672.1 - 0.018 14.7 1.5 0.18 11.5 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 CDO70672.1 - 0.02 14.4 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 CDO70672.1 - 0.022 14.6 0.0 0.73 9.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CDO70672.1 - 0.025 14.3 0.1 9.3 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CDO70672.1 - 0.043 13.7 0.1 1 9.3 0.0 2.4 2 0 0 2 2 2 0 NTPase HD PF01966.22 CDO70672.1 - 0.053 13.7 1.5 1.1 9.5 0.1 2.9 3 0 0 3 3 3 0 HD domain AAA_17 PF13207.6 CDO70672.1 - 0.054 13.9 0.1 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CDO70672.1 - 0.094 11.9 0.0 3.2 6.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 CDO70672.1 - 0.13 12.1 0.1 3.2 7.6 0.0 2.9 3 0 0 3 3 3 0 Adenylylsulphate kinase ATPase PF06745.13 CDO70672.1 - 0.25 10.6 0.5 8 5.7 0.0 2.8 3 0 0 3 3 3 0 KaiC F-box-like PF12937.7 CDO70673.1 - 0.00011 22.1 1.5 0.00055 19.8 1.5 2.2 1 1 0 1 1 1 1 F-box-like Sacchrp_dh_C PF16653.5 CDO70674.1 - 1.7e-78 264.4 0.0 2.4e-78 263.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CDO70674.1 - 7.5e-19 68.3 0.0 1.4e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 CDO70674.1 - 3e-11 43.8 0.0 5e-10 39.8 0.0 2.8 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 CDO70674.1 - 1.2e-05 24.7 0.0 0.02 14.2 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 CDO70674.1 - 0.0012 18.9 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 CDO70674.1 - 0.0069 16.3 0.1 0.016 15.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding MFS_1 PF07690.16 CDO70676.1 - 2e-16 59.9 51.5 9.2e-11 41.3 35.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S10 PF00338.22 CDO70677.1 - 8.9e-30 102.8 0.0 1.6e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Plavaka PF18759.1 CDO70679.1 - 8.7e-16 58.0 0.0 9.9e-16 57.9 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Transposase_21 PF02992.14 CDO70680.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Transposase family tnp2 PCNP PF15473.6 CDO70680.1 - 0.57 10.9 9.1 0.81 10.4 9.1 1.2 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family DivIC PF04977.15 CDO70680.1 - 1.1 9.1 3.4 1.9 8.3 3.4 1.3 1 0 0 1 1 1 0 Septum formation initiator TFIIF_alpha PF05793.12 CDO70680.1 - 3.3 6.2 16.6 4.3 5.8 16.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Intg_mem_TP0381 PF09529.10 CDO70682.1 - 0.086 12.3 0.7 0.13 11.7 0.5 1.4 1 1 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) NOB1_Zn_bind PF08772.11 CDO70684.1 - 0.03 14.5 0.1 0.086 13.0 0.1 1.8 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF3150 PF11348.8 CDO70684.1 - 0.075 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Methyltransf_25 PF13649.6 CDO70685.1 - 0.0057 17.3 0.0 0.022 15.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO70685.1 - 0.012 16.2 0.0 0.036 14.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CDO70685.1 - 0.039 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDO70685.1 - 0.058 14.1 0.0 0.16 12.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PALP PF00291.25 CDO70686.1 - 1.8e-57 195.0 0.1 2.4e-57 194.6 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_hydro_31 PF01055.26 CDO70687.1 - 9.2e-87 292.0 0.0 6.3e-63 213.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CDO70687.1 - 2.6e-17 62.9 0.1 5.7e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like DUF4968 PF16338.5 CDO70687.1 - 0.035 14.4 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4968) Myb_DNA-bind_3 PF12776.7 CDO70688.1 - 1.9e-09 38.3 0.1 3e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO70688.1 - 4.9e-09 36.4 0.2 7.8e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO70688.1 - 0.00097 19.2 0.2 0.0025 17.9 0.2 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CDO70688.1 - 0.0077 16.4 0.3 0.014 15.6 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain TAP42 PF04177.12 CDO70688.1 - 0.034 13.3 0.4 0.048 12.8 0.4 1.2 1 0 0 1 1 1 0 TAP42-like family Myb_DNA-bind_6 PF13921.6 CDO70688.1 - 0.092 13.0 0.2 0.18 12.1 0.2 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain CENP-B_dimeris PF09026.10 CDO70688.1 - 0.39 11.1 6.6 0.68 10.3 6.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 CDO70688.1 - 1.9 6.5 4.7 2.7 6.0 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi PALP PF00291.25 CDO70689.1 - 7.1e-60 202.9 0.2 8.6e-60 202.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pet100 PF09803.9 CDO70690.1 - 1.2e-25 89.8 0.1 1.7e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 Pet100 Copper-bind PF00127.20 CDO70691.1 - 3.4e-05 24.2 0.1 7.3e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Phage_holin_2_4 PF16082.5 CDO70691.1 - 5.3 6.9 7.5 17 5.2 7.5 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF3446 PF11928.8 CDO70691.1 - 8.1 6.8 23.0 3.6 8.0 9.6 2.7 3 0 0 3 3 3 0 Early growth response N-terminal domain DNA_pol_E_B PF04042.16 CDO70693.1 - 2.4e-35 121.8 0.1 1.1e-34 119.6 0.1 1.9 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CDO70693.1 - 5.8e-18 65.2 0.0 1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Pyridoxal_deC PF00282.19 CDO70694.1 - 1.5e-66 224.6 0.0 2e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CDO70694.1 - 6.7e-07 28.6 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Hid1 PF12722.7 CDO70695.1 - 1.3e-173 579.3 0.0 1.6e-173 579.0 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CDO70695.1 - 1.7e-91 307.6 0.0 2.3e-91 307.2 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Rad51 PF08423.11 CDO70696.1 - 0.0027 17.0 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 AvrRpt-cleavage PF05627.11 CDO70696.1 - 0.089 12.2 0.9 0.32 10.4 0.3 2.2 3 0 0 3 3 3 0 Cleavage site for pathogenic type III effector avirulence factor Avr SOG2 PF10428.9 CDO70696.1 - 4.3 6.4 11.8 5.6 6.0 11.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAP2_3 PF14378.6 CDO70697.1 - 0.44 10.2 7.7 0.83 9.3 4.5 2.3 1 1 1 2 2 2 0 PAP2 superfamily DUF4199 PF13858.6 CDO70697.1 - 4.1 7.8 9.0 0.41 11.0 4.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Atg8 PF02991.16 CDO70698.1 - 3.3e-52 175.0 0.1 3.9e-52 174.8 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CDO70698.1 - 6.7e-07 29.6 0.0 9.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF4658 PF15555.6 CDO70699.1 - 0.023 14.8 0.2 0.042 14.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Vps36-NZF-N PF16988.5 CDO70699.1 - 0.086 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PRP21_like_P PF12230.8 CDO70700.1 - 2.6e-50 171.3 14.5 2.6e-50 171.3 14.5 2.5 3 0 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CDO70700.1 - 8.5e-36 121.7 3.1 1.2e-17 63.6 0.1 2.9 3 0 0 3 3 3 2 Surp module ubiquitin PF00240.23 CDO70700.1 - 2.8e-06 27.0 0.0 6.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 CDO70700.1 - 0.00052 19.5 0.2 0.0011 18.5 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger DUF2407 PF10302.9 CDO70700.1 - 0.017 15.7 0.1 0.017 15.7 0.1 3.1 4 0 0 4 4 4 0 DUF2407 ubiquitin-like domain TMEM174 PF15029.6 CDO70700.1 - 0.53 10.0 2.7 0.34 10.6 0.3 1.8 2 0 0 2 2 2 0 Transmembrane protein 174 DUF3915 PF13054.6 CDO70700.1 - 8.2 6.4 17.5 1.7 8.7 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) L31 PF09784.9 CDO70701.1 - 1e-42 144.7 0.2 1.2e-42 144.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 CMS1 PF14617.6 CDO70702.1 - 1.5e-82 276.7 0.3 1.8e-82 276.5 0.3 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RNase_T PF00929.24 CDO70703.1 - 2.2e-12 47.8 0.0 9.4e-05 23.0 0.0 3.8 4 0 0 4 4 4 3 Exonuclease Ndc80_HEC PF03801.13 CDO70705.1 - 1.5e-30 105.9 0.0 3.6e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 CDO70705.1 - 8.1e-05 22.6 3.7 8.1e-05 22.6 3.7 4.1 3 2 2 5 5 5 1 Domain of unknown function (DUF5595) DUF2710 PF10921.8 CDO70705.1 - 0.0099 16.3 3.0 1.7 9.1 0.7 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2710) Fib_alpha PF08702.10 CDO70705.1 - 0.26 11.4 22.4 0.17 12.0 3.7 4.0 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family YabA PF06156.13 CDO70705.1 - 0.55 10.9 24.7 0.51 11.0 4.3 4.3 3 1 1 4 4 4 0 Initiation control protein YabA FapA PF03961.13 CDO70705.1 - 0.77 8.3 19.4 0.91 8.1 10.5 2.7 2 1 0 2 2 2 0 Flagellar Assembly Protein A YojJ PF10372.9 CDO70705.1 - 1 9.5 3.3 11 6.2 0.0 3.5 3 1 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus DUF2935 PF11155.8 CDO70705.1 - 2.3 8.5 10.2 18 5.7 2.6 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) Effector_1 PF04518.12 CDO70705.1 - 3.1 6.8 17.8 1.6 7.8 3.4 3.2 3 0 0 3 3 3 0 Effector from type III secretion system NPV_P10 PF05531.12 CDO70705.1 - 7.2 7.1 13.6 43 4.7 0.0 5.0 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Mog1 PF04603.12 CDO70706.1 - 8.4e-41 139.6 0.1 9.8e-41 139.3 0.1 1.0 1 0 0 1 1 1 1 Ran-interacting Mog1 protein CENP-Q PF13094.6 CDO70707.1 - 0.009 16.2 0.1 0.009 16.2 0.1 2.7 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit HIP1_clath_bdg PF16515.5 CDO70707.1 - 0.029 15.0 1.6 0.029 15.0 1.6 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIVA PF05103.13 CDO70707.1 - 0.066 13.3 17.4 0.05 13.7 3.9 2.3 2 0 0 2 2 2 0 DivIVA protein bZIP_1 PF00170.21 CDO70707.1 - 0.069 13.3 11.9 0.33 11.1 1.6 2.5 2 0 0 2 2 2 0 bZIP transcription factor JIP_LZII PF16471.5 CDO70707.1 - 0.16 12.2 12.5 0.31 11.3 2.0 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF16 PF01519.16 CDO70707.1 - 0.17 12.4 5.2 3.8 8.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Cnn_1N PF07989.11 CDO70707.1 - 0.32 11.2 15.4 1.3 9.3 3.7 2.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 MOSC_N PF03476.16 CDO70707.1 - 0.37 10.7 3.5 1.5 8.7 0.3 2.2 2 0 0 2 2 2 0 MOSC N-terminal beta barrel domain TolA_bind_tri PF16331.5 CDO70707.1 - 0.4 10.8 8.0 4.6 7.4 0.4 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation APC_N_CC PF16689.5 CDO70707.1 - 0.55 10.3 6.8 0.21 11.6 0.9 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain SHE3 PF17078.5 CDO70707.1 - 0.73 9.5 12.2 2.1 8.0 2.2 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ERM PF00769.19 CDO70707.1 - 0.76 9.6 22.6 1.9 8.2 9.1 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family YabA PF06156.13 CDO70707.1 - 0.87 10.3 10.0 5.7 7.6 1.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA WD40_alt PF14077.6 CDO70707.1 - 1.1 9.2 3.9 1.1 9.2 2.1 1.9 2 0 0 2 2 1 0 Alternative WD40 repeat motif GAS PF13851.6 CDO70707.1 - 1.2 8.4 17.4 0.47 9.8 4.5 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DASH_Spc34 PF08657.10 CDO70707.1 - 1.2 8.8 11.7 0.74 9.6 1.9 2.2 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF3450 PF11932.8 CDO70707.1 - 1.4 8.2 12.9 0.71 9.1 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CCDC-167 PF15188.6 CDO70707.1 - 2.5 8.5 8.8 7.6 6.9 0.7 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 eIF3_subunit PF08597.10 CDO70707.1 - 3.4 7.5 17.0 0.12 12.3 1.2 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Peptidase_S46 PF10459.9 CDO70707.1 - 3.7 6.1 8.8 4.4 5.8 3.1 2.0 2 0 0 2 2 2 0 Peptidase S46 GrpE PF01025.19 CDO70707.1 - 4.2 7.0 15.6 2 8.0 3.3 2.2 2 0 0 2 2 2 0 GrpE Cep57_MT_bd PF06657.13 CDO70707.1 - 4.5 7.8 11.5 2.4 8.7 0.6 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.8 CDO70707.1 - 6.3 6.9 14.9 1.3 9.1 3.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mto2_bdg PF12808.7 CDO70707.1 - 6.5 7.1 14.9 0.14 12.5 2.0 3.5 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Cpn60_TCP1 PF00118.24 CDO70709.1 - 3.5e-143 477.8 11.6 4e-143 477.6 11.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 CDO70709.1 - 0.0017 17.9 0.2 0.0046 16.5 0.0 1.8 2 1 0 2 2 2 1 Telomere recombination SCAB_CC PF16712.5 CDO70709.1 - 0.18 11.6 2.8 0.38 10.6 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein ATP-synt_Eps PF04627.13 CDO70709.1 - 3.6 7.6 5.0 1.3 9.0 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial ATP synthase epsilon chain TPR_1 PF00515.28 CDO70710.1 - 1.3e-22 78.6 12.8 2.6e-05 23.8 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 CDO70710.1 - 2.1e-22 77.4 10.3 0.0003 20.7 0.0 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDO70710.1 - 2.9e-19 69.3 9.8 5.6e-06 26.8 0.4 5.8 5 2 1 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CDO70710.1 - 1.7e-13 50.0 6.2 0.00044 19.9 0.1 6.6 5 2 2 7 7 7 3 TPR repeat TPR_17 PF13431.6 CDO70710.1 - 2.4e-13 49.5 1.3 0.043 14.2 0.1 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 CDO70710.1 - 5.7e-13 48.5 5.4 0.0085 16.8 0.0 7.2 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDO70710.1 - 7.6e-13 48.9 12.9 0.0065 17.1 0.1 6.0 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 CDO70710.1 - 7.4e-11 41.4 6.7 0.34 11.2 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDO70710.1 - 1.9e-10 40.9 12.7 0.047 14.0 0.2 6.0 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 CDO70710.1 - 2.2e-09 37.4 6.3 2.5 8.9 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO70710.1 - 1.3e-08 34.9 12.9 0.055 13.7 0.5 5.2 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CDO70710.1 - 5.5e-08 32.9 6.9 0.0014 18.7 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 CDO70710.1 - 0.00014 21.2 11.2 0.056 12.7 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat PPTA PF01239.22 CDO70710.1 - 0.0054 16.4 0.1 4.2 7.2 0.0 2.7 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat TPR_10 PF13374.6 CDO70710.1 - 0.026 14.4 4.0 4.6 7.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 CDO70710.1 - 0.035 14.2 2.5 0.57 10.3 1.1 3.3 3 1 1 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 CDO70710.1 - 0.14 12.5 0.8 0.41 11.0 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDO70710.1 - 0.18 11.9 4.2 1.6 8.9 0.2 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat SRR1 PF07985.12 CDO70712.1 - 5.1e-17 61.6 0.8 8.5e-17 60.9 0.8 1.4 1 0 0 1 1 1 1 SRR1 Pre-PUA PF17832.1 CDO70713.1 - 4.7e-22 78.5 0.2 7.3e-22 77.9 0.2 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CDO70713.1 - 5.4e-16 58.3 0.0 7.9e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CDO70713.1 - 0.034 14.5 0.2 0.066 13.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) CRM1_C PF08767.11 CDO70714.1 - 5.2e-134 446.4 0.2 5.2e-134 446.4 0.2 3.5 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 CDO70714.1 - 2.4e-42 144.5 8.7 2.2e-41 141.4 6.4 3.5 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CDO70714.1 - 9.5e-34 114.9 4.7 2.6e-33 113.5 4.7 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CDO70714.1 - 7.1e-32 109.3 2.8 2.6e-31 107.5 1.3 2.9 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CDO70714.1 - 3.7e-19 67.9 2.6 3.7e-19 67.9 2.6 2.4 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CDO70714.1 - 2.9e-13 49.5 0.0 1.3e-12 47.4 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 CDO70714.1 - 0.011 15.7 0.1 0.17 11.8 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 CDO70714.1 - 0.075 13.6 1.3 7.6 7.2 0.0 3.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region UME PF08064.13 CDO70714.1 - 0.11 12.4 0.2 16 5.5 0.0 3.7 2 1 0 2 2 2 0 UME (NUC010) domain DUF2935 PF11155.8 CDO70714.1 - 1.6 9.1 4.8 18 5.7 0.2 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) Spc24 PF08286.11 CDO70715.1 - 4.8e-19 68.5 0.1 1.1e-18 67.4 0.0 1.6 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 YscO-like PF16789.5 CDO70715.1 - 0.011 15.7 0.7 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 YscO-like protein FAM76 PF16046.5 CDO70715.1 - 0.054 12.8 0.8 0.072 12.4 0.8 1.1 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 CDO70715.1 - 0.33 11.5 6.8 0.69 10.4 6.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4200 PF13863.6 CDO70715.1 - 0.37 11.2 2.7 0.98 9.8 2.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CAF1A PF12253.8 CDO70716.1 - 2.8e-21 75.4 2.3 2.8e-21 75.4 2.3 2.4 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A PCRF PF03462.18 CDO70716.1 - 8.8 6.1 7.7 1 9.2 1.3 2.4 2 0 0 2 2 2 0 PCRF domain OmpH PF03938.14 CDO70716.1 - 9.7 6.5 13.7 11 6.4 3.4 2.9 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) AAA PF00004.29 CDO70717.1 - 4.3e-15 56.3 0.0 7.7e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CDO70717.1 - 2.3e-11 43.8 0.0 1.3e-09 38.0 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CDO70717.1 - 1.2e-09 38.4 0.0 4.1e-09 36.7 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 CDO70717.1 - 3.8e-07 30.5 0.0 8e-06 26.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 CDO70717.1 - 5e-07 29.8 0.0 1.1e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CDO70717.1 - 1.2e-05 25.8 0.1 9.6e-05 22.8 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 CDO70717.1 - 1.5e-05 25.3 0.0 3.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 CDO70717.1 - 6.4e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDO70717.1 - 0.0004 20.2 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 CDO70717.1 - 0.00055 19.7 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDO70717.1 - 0.00073 19.5 0.0 0.0021 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CDO70717.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CDO70717.1 - 0.0024 17.4 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 CDO70717.1 - 0.0039 17.2 0.0 0.02 14.9 0.0 2.1 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CDO70717.1 - 0.0067 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDO70717.1 - 0.0074 16.6 0.0 0.056 13.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CDO70717.1 - 0.0095 15.3 0.0 0.094 12.1 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CDO70717.1 - 0.014 15.7 0.0 0.058 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CDO70717.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 CDO70717.1 - 0.035 13.9 0.1 0.53 10.0 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase DUF815 PF05673.13 CDO70717.1 - 0.044 12.9 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_2 PF07724.14 CDO70717.1 - 0.047 13.8 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF881 PF05949.12 CDO70717.1 - 0.055 13.3 0.1 2.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF881) DNA_pol3_delta PF06144.13 CDO70717.1 - 0.066 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PhoH PF02562.16 CDO70717.1 - 0.075 12.5 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 CDO70717.1 - 0.098 11.7 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 CDO70717.1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDO70717.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDO70717.1 - 0.2 12.1 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase HSP70 PF00012.20 CDO70718.1 - 2.3e-237 789.0 4.9 2.6e-237 788.8 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDO70718.1 - 1.7e-17 63.3 0.2 1.4e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 CDO70718.1 - 0.01 15.3 1.2 4.5 6.7 0.0 2.9 3 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 CDO70718.1 - 0.022 13.7 1.5 0.16 11.0 0.1 2.6 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 CDO70718.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 CDO70718.1 - 0.052 12.8 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 StbA protein Ribosomal_S2 PF00318.20 CDO70719.1 - 3e-55 186.8 0.1 1.2e-32 112.9 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Chorismate_bind PF00425.18 CDO70720.1 - 6e-88 294.7 0.0 1.2e-87 293.8 0.0 1.5 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 CDO70720.1 - 1.1e-27 97.0 0.0 3.7e-27 95.3 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region SHQ1 PF04925.15 CDO70721.1 - 1e-58 197.8 0.0 1.7e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 SHQ1 protein CS PF04969.16 CDO70721.1 - 1.2e-05 26.2 0.0 2.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 CS domain PIH1_CS PF18201.1 CDO70721.1 - 5.4e-05 23.5 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain WSD PF15613.6 CDO70721.1 - 0.025 15.1 0.7 0.064 13.7 0.6 1.7 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif UAA PF08449.11 CDO70723.1 - 0.03 13.5 0.4 0.059 12.6 0.4 1.4 1 0 0 1 1 1 0 UAA transporter family EamA PF00892.20 CDO70723.1 - 0.22 11.7 22.0 0.23 11.6 8.3 2.9 3 0 0 3 3 3 0 EamA-like transporter family E1-E2_ATPase PF00122.20 CDO70724.1 - 4.9e-53 179.3 1.5 4.9e-53 179.3 1.5 3.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDO70724.1 - 6.7e-46 156.3 9.2 6.7e-46 156.3 9.2 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDO70724.1 - 9.8e-22 78.3 0.6 2.2e-20 73.9 0.6 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDO70724.1 - 1.4e-21 75.9 0.3 2.6e-20 71.9 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CDO70724.1 - 9.1e-18 64.1 0.0 1.9e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDO70724.1 - 1.7e-07 31.2 1.1 2.1e-06 27.7 1.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1772 PF08592.11 CDO70724.1 - 2.3e-05 24.7 0.0 2.3e-05 24.7 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1772) HAD PF12710.7 CDO70724.1 - 0.0015 19.0 0.0 0.0039 17.6 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DPBB_1 PF03330.18 CDO70726.1 - 4.7e-09 36.4 0.5 1.6e-08 34.7 0.2 2.1 1 1 1 2 2 2 1 Lytic transglycolase DPBB_1 PF03330.18 CDO70727.1 - 0.0041 17.4 0.0 0.016 15.5 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase SOG2 PF10428.9 CDO70727.1 - 0.16 11.1 16.2 0.22 10.7 16.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Podoplanin PF05808.11 CDO70727.1 - 3.1 7.9 15.2 5.9 7.0 14.7 1.6 2 0 0 2 2 2 0 Podoplanin Hamartin PF04388.12 CDO70727.1 - 3.6 6.1 9.8 4.2 5.9 9.8 1.1 1 0 0 1 1 1 0 Hamartin protein Apt1 PF10351.9 CDO70727.1 - 5.3 5.8 6.7 7.1 5.4 6.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DPBB_1 PF03330.18 CDO70728.1 - 0.019 15.2 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Lytic transglycolase Miga PF10265.9 CDO70728.1 - 1.5 7.7 2.4 1.8 7.4 2.4 1.1 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 CDO70728.1 - 4.1 6.1 7.4 5.8 5.6 7.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CDO70728.1 - 5.6 6.8 16.5 8 6.3 16.5 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 CDO70728.1 - 8.8 5.4 19.5 12 4.9 19.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Med3 PF11593.8 CDO70729.1 - 0.032 13.4 13.9 0.047 12.9 13.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SOBP PF15279.6 CDO70729.1 - 0.45 11.1 8.8 0.67 10.5 8.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.9 CDO70729.1 - 1.8 7.0 5.8 2.6 6.5 5.8 1.3 1 0 0 1 1 1 0 Macoilin family DUF3827 PF12877.7 CDO70729.1 - 2.1 6.6 9.0 3.4 5.9 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) RCC1 PF00415.18 CDO70730.1 - 5e-24 84.7 8.4 1.6e-08 35.0 0.0 8.2 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDO70730.1 - 4.6e-12 45.4 7.5 9.1e-05 22.2 0.1 5.7 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat DSBA PF01323.20 CDO70732.1 - 0.04 13.7 0.1 0.057 13.2 0.1 1.4 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Hist_deacetyl PF00850.19 CDO70733.1 - 5.1e-83 279.1 0.0 6.6e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RRM_1 PF00076.22 CDO70734.1 - 8.9e-25 86.3 0.0 1.4e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 CDO70734.1 - 5e-22 76.3 0.0 3.1e-05 23.4 0.0 5.7 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 CDO70734.1 - 0.00053 19.8 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 CDO70734.1 - 0.22 11.0 0.0 1.5 8.2 0.0 2.0 2 0 0 2 2 2 0 RNA-recognition motif Linker_histone PF00538.19 CDO70736.1 - 1.2e-08 35.2 0.1 1.2e-08 35.2 0.1 3.3 2 2 1 3 3 3 1 linker histone H1 and H5 family RNA_pol_Rpc82 PF05645.13 CDO70737.1 - 1.6e-16 60.9 0.3 5.9e-14 52.4 0.1 3.2 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 CDO70737.1 - 1.4e-14 53.9 0.1 1.1e-11 44.6 0.1 3.4 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 CDO70737.1 - 1.9e-11 43.8 0.1 4.7e-06 26.4 0.0 4.1 4 0 0 4 4 4 2 TFIIE alpha subunit AMP-binding PF00501.28 CDO70739.1 - 3.2e-18 65.6 0.0 7.1e-18 64.4 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme SPT16 PF08644.11 CDO70740.1 - 4.2e-58 195.8 1.6 5.3e-58 195.5 0.2 2.0 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 CDO70740.1 - 3e-40 137.6 0.6 1.8e-39 135.1 0.0 2.7 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 CDO70740.1 - 1.5e-26 93.4 0.0 2.3e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CDO70740.1 - 6.7e-15 55.3 0.0 2.6e-14 53.4 0.0 2.1 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 CDO70740.1 - 0.088 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) PriA_C PF18074.1 CDO70742.1 - 0.005 17.6 0.3 1.6 9.6 0.0 2.9 2 1 1 3 3 3 2 Primosomal protein N C-terminal domain EzrA PF06160.12 CDO70742.1 - 0.0096 14.1 0.1 0.27 9.4 0.1 2.0 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA Abhydrolase_1 PF00561.20 CDO70743.1 - 1.3e-20 74.1 0.0 5.2e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO70743.1 - 1.1e-14 54.3 0.0 2.2e-14 53.3 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO70743.1 - 2.2e-14 54.6 0.0 2.7e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CDO70743.1 - 0.0016 18.3 0.0 0.012 15.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 CDO70743.1 - 0.0076 16.1 0.0 0.029 14.2 0.0 1.8 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_4 PF08386.10 CDO70743.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Thioesterase PF00975.20 CDO70743.1 - 0.033 14.3 0.0 0.082 13.0 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Ndr PF03096.14 CDO70743.1 - 0.039 12.7 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family Peptidase_S9 PF00326.21 CDO70743.1 - 0.052 13.0 0.0 2 7.9 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family UPF0227 PF05728.12 CDO70743.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DLH PF01738.18 CDO70743.1 - 0.14 11.7 0.0 12 5.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Helicase_C PF00271.31 CDO70744.1 - 2.1e-12 47.3 0.1 1.6e-11 44.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 CDO70744.1 - 8.2e-08 32.9 0.8 5.3e-07 30.3 0.8 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.11 CDO70744.1 - 3.6e-06 27.4 0.0 7.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like DEAD PF00270.29 CDO70744.1 - 4.4e-05 23.3 0.0 9.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pkinase PF00069.25 CDO70745.1 - 4.4e-17 62.3 0.0 6.9e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70745.1 - 1.5e-09 37.5 0.0 3.5e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase MBOAT_2 PF13813.6 CDO70746.1 - 1.2e-26 92.8 20.8 2.6e-14 53.2 5.2 3.7 4 0 0 4 4 4 2 Membrane bound O-acyl transferase family Cytochrom_B561 PF03188.16 CDO70748.1 - 4.5e-05 23.6 3.6 0.00051 20.2 3.6 2.4 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 NAD_binding_2 PF03446.15 CDO70749.1 - 4.9e-36 124.3 0.1 8.8e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CDO70749.1 - 1.7e-30 105.8 0.0 3.6e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sec7 PF01369.20 CDO70750.1 - 2.3e-68 229.5 0.3 4e-68 228.7 0.3 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDO70750.1 - 9.8e-19 67.8 0.9 1.6e-17 63.8 0.0 3.0 2 2 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CDO70750.1 - 0.00013 21.8 0.7 0.74 9.7 0.0 4.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) RIX1 PF08167.12 CDO70750.1 - 0.35 10.6 5.0 5.3 6.7 0.3 2.9 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Proteasome PF00227.26 CDO70751.1 - 2.3e-59 200.1 0.0 3.3e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDO70751.1 - 2.5e-14 52.6 0.3 1.1e-13 50.6 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_C78 PF07910.13 CDO70753.1 - 3.7e-39 134.4 0.0 5.4e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 dbPDZ_assoc PF16610.5 CDO70753.1 - 0.15 12.3 0.2 0.15 12.3 0.2 2.6 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 MAT1 PF06391.13 CDO70754.1 - 5.4e-60 202.7 11.9 6.3e-60 202.5 11.9 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 UPF0242 PF06785.11 CDO70754.1 - 0.39 10.8 13.1 0.56 10.3 13.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1682 PF07946.14 CDO70754.1 - 9.9 5.3 17.6 4.1 6.5 15.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) LigB PF02900.18 CDO70755.1 - 2.2e-34 118.8 0.0 2.8e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Pkinase PF00069.25 CDO70756.1 - 2.2e-65 220.6 0.0 2.8e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70756.1 - 1.1e-30 106.8 0.0 1.5e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO70756.1 - 0.0004 19.8 0.0 0.00069 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Brix PF04427.18 CDO70757.1 - 9.8e-45 153.0 0.0 1.4e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain COPI_C PF06957.11 CDO70757.1 - 2.5 6.8 18.4 4.8 5.8 18.4 1.5 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus eIF-3c_N PF05470.12 CDO70757.1 - 2.6 6.3 14.7 0.91 7.8 12.4 1.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.10 CDO70757.1 - 3.7 6.8 38.7 0.035 13.5 30.2 1.8 3 0 0 3 3 3 0 BUD22 TFIIA PF03153.13 CDO70757.1 - 8.2 6.3 20.7 12 5.8 20.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CSRNP_N PF16019.5 CDO70757.1 - 9.9 6.0 10.1 7.8 6.3 8.7 1.5 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Cyto_heme_lyase PF01265.17 CDO70758.1 - 2.5e-45 155.3 7.7 2.5e-43 148.8 7.7 2.7 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase NMO PF03060.15 CDO70759.1 - 3.3e-56 191.1 0.8 5.3e-56 190.4 0.8 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CDO70759.1 - 6.3e-10 38.6 0.1 1.2e-07 31.1 0.1 2.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CDO70759.1 - 0.00037 19.6 3.1 0.00066 18.8 3.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 CDO70759.1 - 0.11 11.7 0.4 0.16 11.1 0.4 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase WD40 PF00400.32 CDO70760.1 - 1.9e-14 53.8 8.0 7.5e-06 26.6 0.0 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CDO70760.1 - 0.0002 20.3 1.1 0.77 8.4 0.0 4.0 2 2 3 5 5 5 3 Nup133 N terminal like ANAPC4_WD40 PF12894.7 CDO70760.1 - 0.0013 19.0 0.1 0.33 11.3 0.0 3.0 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDO70760.1 - 0.036 12.7 0.3 0.48 9.0 1.1 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 CAP_N PF01213.19 CDO70760.1 - 0.52 9.7 7.2 0.83 9.1 1.5 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Med4 PF10018.9 CDO70761.1 - 0.041 13.6 3.6 3.7 7.2 1.1 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Lsm_C PF14894.6 CDO70761.1 - 0.57 10.0 1.7 1.2 9.0 0.4 2.2 3 0 0 3 3 3 0 Lsm C-terminal TPR_14 PF13428.6 CDO70762.1 - 2.7e-08 34.0 22.6 0.31 12.0 0.1 12.6 9 3 5 14 14 13 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDO70762.1 - 4.3e-07 30.4 4.3 1.1 9.8 0.1 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat Suf PF05843.14 CDO70762.1 - 1.9e-06 28.1 8.6 5.2e-05 23.4 3.0 4.6 3 1 0 4 4 4 1 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 CDO70762.1 - 3.5e-05 23.8 7.7 3 7.8 0.3 6.4 5 1 2 7 7 7 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 CDO70762.1 - 7.5e-05 22.9 10.3 0.018 15.3 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDO70762.1 - 0.00018 21.5 11.5 3.3 8.1 0.2 7.8 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDO70762.1 - 0.0011 18.7 1.7 2.5 8.1 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDO70762.1 - 0.0016 18.4 17.6 0.076 13.2 0.1 7.8 10 0 0 10 10 9 2 Tetratricopeptide repeat NRDE-2 PF08424.10 CDO70762.1 - 0.051 12.7 15.2 1.3 8.1 0.1 5.7 2 2 3 6 6 6 0 NRDE-2, necessary for RNA interference DUF627 PF04781.12 CDO70762.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF627) MIT PF04212.18 CDO70762.1 - 0.09 12.9 1.2 2.6 8.2 0.0 3.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 CDO70762.1 - 0.19 11.8 4.8 17 5.7 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDO70762.1 - 0.3 11.5 6.5 2.2e+02 2.6 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat PPTA PF01239.22 CDO70763.1 - 3e-25 87.1 15.1 2.3e-09 36.7 2.7 5.0 4 1 1 5 5 5 4 Protein prenyltransferase alpha subunit repeat Vps8 PF12816.7 CDO70763.1 - 0.029 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 Ge1_WD40 PF16529.5 CDO70764.1 - 0.17 10.8 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Dioxygenase_C PF00775.21 CDO70765.1 - 9.4e-46 155.5 0.0 1.3e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 CDO70765.1 - 9.1e-29 99.1 0.0 1.8e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 CDO70765.1 - 0.0094 16.2 0.0 0.074 13.3 0.0 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain ACOX PF01756.19 CDO70765.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA oxidase Got1 PF04178.12 CDO70766.1 - 9.6e-18 64.6 21.9 3.9e-17 62.7 21.9 1.9 1 1 0 1 1 1 1 Got1/Sft2-like family HAGH_C PF16123.5 CDO70767.1 - 3.4e-20 72.3 0.0 7.7e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CDO70767.1 - 4.3e-06 26.9 5.4 0.00017 21.7 5.4 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDO70767.1 - 0.02 14.4 1.2 0.1 12.1 1.2 2.1 1 1 0 1 1 1 0 Beta-lactamase superfamily domain TMEM51 PF15345.6 CDO70768.1 - 0.012 15.5 0.3 0.035 13.9 0.3 1.9 1 1 0 1 1 1 0 Transmembrane protein 51 Herpes_gE PF02480.16 CDO70768.1 - 0.096 11.4 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 CDO70768.1 - 0.14 13.1 0.0 0.28 12.1 0.0 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 CDO70770.1 - 0.078 12.8 0.1 0.19 11.5 0.0 1.7 1 1 1 2 2 2 0 Transmembrane protein 51 TSP9 PF11493.8 CDO70770.1 - 1.1 10.0 3.6 8.9 7.1 0.0 2.9 3 1 0 3 3 3 0 Thylakoid soluble phosphoprotein TSP9 FAM199X PF15814.5 CDO70770.1 - 3.1 6.8 9.8 4.9 6.1 9.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X IATP PF04568.12 CDO70770.1 - 3.8 8.0 7.2 1.7 9.1 0.1 2.7 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP Piwi PF02171.17 CDO70771.1 - 3.7e-72 243.1 0.0 9.2e-72 241.8 0.0 1.7 2 0 0 2 2 2 1 Piwi domain ArgoL1 PF08699.10 CDO70771.1 - 5.9e-16 57.9 0.1 1.4e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 CDO70771.1 - 7e-10 39.7 0.0 1.6e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 CDO70771.1 - 7.6e-06 26.1 0.1 2.5e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 CDO70771.1 - 8e-05 22.5 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 CDO70771.1 - 0.00044 20.5 0.0 0.0018 18.6 0.0 2.2 1 0 0 1 1 1 1 Argonaute linker 2 domain SRP-alpha_N PF04086.13 CDO70772.1 - 5.4e-48 164.4 8.6 4.4e-46 158.1 8.6 2.2 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 CDO70772.1 - 1.5e-45 155.3 0.2 7.1e-45 153.1 0.2 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 CDO70772.1 - 5.8e-09 36.0 0.0 2.4e-08 34.0 0.0 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 CDO70772.1 - 4.3e-05 22.6 0.1 0.00011 21.3 0.1 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CDO70772.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CDO70772.1 - 0.0085 16.2 0.1 0.025 14.6 0.1 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 CDO70772.1 - 0.011 15.7 0.0 0.034 14.1 0.0 1.8 1 1 0 1 1 1 0 NTPase AAA_24 PF13479.6 CDO70772.1 - 0.021 14.6 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 CDO70772.1 - 0.053 13.0 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 CDO70772.1 - 0.057 12.6 0.6 2.7 7.1 0.1 2.3 1 1 1 2 2 2 0 Anion-transporting ATPase AAA_31 PF13614.6 CDO70772.1 - 0.071 13.0 0.1 1.7 8.5 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDO70772.1 - 0.081 13.3 1.3 0.46 10.9 0.0 2.6 2 2 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CDO70772.1 - 0.14 12.4 0.0 1.1 9.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CDO70772.1 - 0.19 11.8 0.4 1.4 9.0 0.4 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Img2 PF05046.14 CDO70774.1 - 1.1e-11 44.9 0.2 1.7e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial large subunit ribosomal protein (Img2) INT_SG_DDX_CT_C PF15300.6 CDO70774.1 - 0.067 13.0 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus DUF1905 PF08922.11 CDO70774.1 - 0.17 12.0 0.0 12 6.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) ASD2 PF08687.11 CDO70774.1 - 0.25 10.9 0.0 0.46 10.0 0.0 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Glyco_hydro_43 PF04616.14 CDO70775.1 - 2.2e-16 60.0 3.2 3.3e-16 59.5 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SOR_SNZ PF01680.17 CDO70776.1 - 4.1e-111 369.7 5.3 5.9e-111 369.2 5.3 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 CDO70776.1 - 8.9e-11 41.6 3.4 1.4e-07 31.1 0.1 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 CDO70776.1 - 1.2e-05 24.6 0.2 0.099 11.7 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 CDO70776.1 - 0.00019 21.5 0.0 0.00051 20.1 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 CDO70776.1 - 0.0043 16.3 0.2 0.1 11.8 0.0 2.3 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 CDO70776.1 - 0.0051 16.2 4.4 0.14 11.5 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 CDO70776.1 - 0.0093 15.5 0.2 0.2 11.1 0.0 2.6 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 CDO70776.1 - 0.016 14.4 0.0 0.53 9.4 0.0 2.6 2 1 1 3 3 3 0 Indole-3-glycerol phosphate synthase RNA_pol_Rpc4 PF05132.14 CDO70776.1 - 0.12 12.8 0.1 0.2 12.1 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Cyclin_N PF00134.23 CDO70779.1 - 2.8e-09 36.8 0.0 9e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Ras PF00071.22 CDO70780.1 - 3.1e-65 218.7 1.5 3.9e-65 218.4 1.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO70780.1 - 1.6e-36 125.1 1.3 2.2e-36 124.7 0.1 1.8 2 1 1 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO70780.1 - 3.3e-17 62.5 0.2 4.1e-17 62.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDO70780.1 - 6.6e-08 32.6 2.4 0.00045 20.2 0.9 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDO70780.1 - 9.5e-06 25.7 0.2 5.5e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDO70780.1 - 1.1e-05 24.9 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDO70780.1 - 1.2e-05 24.8 0.1 1.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDO70780.1 - 1.7e-05 24.4 0.5 3.8e-05 23.3 0.4 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CDO70780.1 - 0.0019 18.6 0.3 0.012 16.0 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CDO70780.1 - 0.0035 17.8 0.7 0.52 10.7 0.0 2.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 CDO70780.1 - 0.01 15.4 0.1 0.057 13.0 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 CDO70780.1 - 0.015 14.8 1.3 0.18 11.3 0.0 2.6 2 1 1 3 3 3 0 P-loop containing dynein motor region AAA_29 PF13555.6 CDO70780.1 - 0.023 14.4 0.9 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CDO70780.1 - 0.028 14.7 0.6 0.067 13.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 CDO70780.1 - 0.035 14.1 0.0 0.066 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CDO70780.1 - 0.064 13.8 0.5 0.15 12.5 0.5 1.9 1 1 0 1 1 1 0 ABC transporter Septin PF00735.18 CDO70780.1 - 0.073 12.3 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin TniB PF05621.11 CDO70780.1 - 0.1 12.0 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Asp PF00026.23 CDO70781.1 - 2.1e-47 162.1 0.1 2.8e-47 161.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO70781.1 - 7.3e-07 29.6 3.3 0.00018 21.8 3.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO70781.1 - 0.0019 18.8 1.9 0.042 14.5 0.5 3.2 2 2 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDO70781.1 - 0.12 12.9 0.5 1.4 9.6 0.1 2.9 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease zinc_ribbon_15 PF17032.5 CDO70782.1 - 0.0064 17.2 0.0 0.0092 16.7 0.0 1.2 1 0 0 1 1 1 1 zinc-ribbon family Zn_clus PF00172.18 CDO70783.1 - 1e-06 28.7 4.5 1.9e-06 27.8 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.10 CDO70784.1 - 7.1e-41 140.6 0.0 8.3e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Peripla_BP_1 PF00532.21 CDO70784.1 - 0.076 12.4 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family HAD_2 PF13419.6 CDO70785.1 - 9.8e-07 29.0 0.0 3.8e-06 27.1 0.0 2.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDO70785.1 - 0.00081 19.4 0.0 0.0024 17.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 CDO70785.1 - 0.013 15.8 0.0 0.21 11.8 0.0 2.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDO70785.1 - 0.04 14.0 0.0 0.22 11.7 0.0 2.1 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase EF-hand_6 PF13405.6 CDO70786.1 - 5.1e-13 47.8 0.0 4.6e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CDO70786.1 - 6.1e-12 44.2 0.0 9.8e-06 24.8 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 CDO70786.1 - 2.2e-10 39.6 0.0 1.7e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDO70786.1 - 5.4e-09 36.4 0.0 0.0005 20.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDO70786.1 - 6e-06 26.0 0.0 0.22 11.4 0.0 3.2 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 CDO70786.1 - 0.0011 19.2 0.0 0.61 10.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 CDO70786.1 - 0.054 13.4 0.0 0.31 10.9 0.0 1.9 1 1 1 2 2 2 0 Caleosin related protein AMP-binding PF00501.28 CDO70787.1 - 2.2e-43 148.5 0.0 2.7e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 CDO70788.1 - 3e-28 98.6 0.1 4.2e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDO70788.1 - 8e-06 26.7 1.0 2.4e-05 25.2 1.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 CDO70789.1 - 1.2e-28 100.1 30.0 1.2e-28 100.1 30.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO70789.1 - 5.8e-06 25.4 0.5 5.8e-06 25.4 0.5 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter PIG-Y PF15159.6 CDO70791.1 - 1.9e-23 83.2 1.5 2.7e-23 82.7 1.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y CLTH PF10607.9 CDO70792.1 - 7.7e-19 68.0 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CDO70792.1 - 1.7e-07 31.1 0.2 2.9e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 CDO70792.1 - 0.00075 18.9 1.4 0.00082 18.8 0.0 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_5 PF14634.6 CDO70792.1 - 0.0045 16.9 0.2 0.008 16.1 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CDO70792.1 - 0.0076 16.6 0.3 0.013 15.8 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 CDO70792.1 - 0.059 13.2 1.4 0.12 12.2 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 CDO70792.1 - 0.14 12.1 0.8 0.25 11.3 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDO70792.1 - 0.21 11.5 0.2 0.4 10.6 0.2 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Pirin PF02678.16 CDO70794.1 - 6.5e-29 100.1 0.1 1.2e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 CDO70794.1 - 7.8e-28 96.9 0.0 2.3e-27 95.4 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 CDO70794.1 - 0.00025 20.7 0.6 0.075 12.8 0.6 2.7 2 0 0 2 2 2 2 Cupin domain AA_permease PF00324.21 CDO70795.1 - 2.4e-126 422.1 40.7 3e-126 421.8 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CDO70795.1 - 9e-33 113.7 42.3 1.5e-32 113.0 42.3 1.3 1 1 0 1 1 1 1 Amino acid permease ECH_1 PF00378.20 CDO70796.1 - 3.3e-24 85.6 0.0 3.8e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDO70796.1 - 7.9e-17 61.7 0.0 9e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Prenyltrans PF00432.21 CDO70797.1 - 7.4e-54 179.2 4.6 2.5e-12 46.3 0.0 7.1 7 0 0 7 7 7 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CDO70797.1 - 0.00047 19.4 0.0 0.62 9.1 0.0 3.0 1 1 2 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CDO70797.1 - 0.037 13.1 0.0 0.11 11.6 0.0 1.6 1 1 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Herpes_IR6 PF06307.12 CDO70797.1 - 0.18 11.3 0.0 1 8.9 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus IR6 protein HEAT_2 PF13646.6 CDO70798.1 - 0.024 15.0 0.5 0.71 10.3 0.2 3.7 3 1 0 3 3 3 0 HEAT repeats NUC130_3NT PF08158.12 CDO70798.1 - 0.043 14.1 0.3 28 5.1 0.0 3.7 4 0 0 4 4 4 0 NUC130/3NT domain Nexin_C PF08628.12 CDO70798.1 - 0.21 12.2 1.5 1.3 9.6 0.1 2.9 3 0 0 3 3 3 0 Sorting nexin C terminal RWD PF05773.22 CDO70799.1 - 6e-20 71.7 1.6 6.8e-20 71.5 0.1 1.9 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 CDO70799.1 - 3.4e-08 33.9 11.5 3.4e-08 33.9 11.5 2.5 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 FinO_N PF12602.8 CDO70799.1 - 0.22 11.9 3.3 0.48 10.8 3.3 1.6 1 0 0 1 1 1 0 Fertility inhibition protein N terminal Ribosomal_S21 PF01165.20 CDO70800.1 - 1.9e-08 33.9 3.6 3.1e-08 33.2 3.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Cyclin_N PF00134.23 CDO70802.1 - 5.4e-09 35.9 0.9 9.1e-09 35.1 0.4 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDO70802.1 - 9e-05 22.5 0.2 0.055 13.6 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.19 CDO70802.1 - 0.00015 21.7 0.5 0.0054 16.8 0.2 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 CDO70802.1 - 0.014 15.7 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 Cyclin C-terminal domain IF-2B PF01008.17 CDO70803.1 - 4.9e-59 199.9 0.0 6.3e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family CLASP_N PF12348.8 CDO70805.1 - 1.9e-26 93.0 0.0 2.3e-06 27.3 0.0 5.2 5 0 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 CDO70805.1 - 1.6e-11 43.4 18.0 0.83 10.1 0.0 12.3 13 0 0 13 13 13 3 HEAT repeat HEAT_2 PF13646.6 CDO70805.1 - 4.2e-08 33.5 17.3 5.4 7.5 0.0 9.7 7 2 2 10 10 10 4 HEAT repeats Cnd1 PF12717.7 CDO70805.1 - 1.7e-06 28.2 0.2 14 5.7 0.0 7.2 7 1 0 8 8 8 2 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 CDO70805.1 - 0.00011 21.9 1.2 11 5.5 0.0 6.0 5 2 2 7 7 7 2 Dos2-interacting transcription regulator of RNA-Pol-II Adaptin_N PF01602.20 CDO70805.1 - 0.00017 20.3 0.8 3 6.3 0.2 4.8 6 0 0 6 6 6 2 Adaptin N terminal region TAN PF11640.8 CDO70805.1 - 0.00051 20.2 7.2 0.024 14.8 0.1 4.9 5 0 0 5 5 5 2 Telomere-length maintenance and DNA damage repair RTP1_C1 PF10363.9 CDO70805.1 - 0.11 12.7 0.3 12 6.1 0.0 4.5 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Acyltransferase PF01553.21 CDO70806.1 - 4.9e-10 39.2 0.0 9.1e-09 35.0 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Peptidase_M24 PF00557.24 CDO70807.1 - 6e-46 156.8 0.0 7.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 FAA_hydrolase PF01557.18 CDO70807.1 - 0.058 13.1 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.19 CDO70808.1 - 8.4e-22 77.9 0.5 2e-13 50.3 0.1 3.1 2 1 1 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.12 CDO70808.1 - 0.00098 18.3 0.0 0.62 9.0 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein SE PF08491.10 CDO70808.1 - 0.055 12.5 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase ANAPC5 PF12862.7 CDO70809.1 - 3.8e-08 33.3 0.1 7.1e-07 29.2 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 5 HNH_2 PF13391.6 CDO70811.1 - 3e-05 24.1 0.2 9.9e-05 22.4 0.0 2.0 2 1 0 2 2 2 1 HNH endonuclease FAD-oxidase_C PF02913.19 CDO70812.1 - 5e-58 196.7 0.0 7.3e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDO70812.1 - 1e-24 86.9 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain RRM_1 PF00076.22 CDO70812.1 - 0.034 14.0 0.1 2.2 8.1 0.0 3.4 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PQ-loop PF04193.14 CDO70813.1 - 1.6e-11 43.8 0.8 3.2e-11 42.8 0.8 1.5 1 0 0 1 1 1 1 PQ loop repeat eIF3_N PF09440.10 CDO70814.1 - 2e-48 164.2 6.4 3.5e-48 163.4 3.1 2.5 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 CDO70814.1 - 1.5e-09 38.3 0.0 3.7e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain PARP_reg PF02877.14 CDO70814.1 - 0.13 12.3 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain MSP1b PF03429.13 CDO70814.1 - 0.17 10.0 0.0 0.31 9.1 0.0 1.3 1 0 0 1 1 1 0 Major surface protein 1B RIH_assoc PF08454.11 CDO70814.1 - 0.18 11.6 0.5 0.41 10.5 0.5 1.6 1 0 0 1 1 1 0 RyR and IP3R Homology associated HECT PF00632.25 CDO70815.1 - 6.6e-96 321.4 0.0 9.4e-96 320.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) V-ATPase_H_N PF03224.14 CDO70815.1 - 0.096 12.0 0.1 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 V-ATPase subunit H IQ PF00612.27 CDO70815.1 - 0.11 12.3 1.0 0.48 10.3 1.0 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif HRI1 PF16815.5 CDO70817.1 - 1.2e-20 74.2 0.2 9.6e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 Protein HRI1 Asp PF00026.23 CDO70820.1 - 0.026 14.0 0.0 0.18 11.2 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic aspartyl protease Mit_KHE1 PF10173.9 CDO70821.1 - 5.7e-31 108.1 0.0 8.2e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Pro-kuma_activ PF09286.11 CDO70822.1 - 1.1e-31 110.0 0.0 4.9e-31 107.9 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain mRNA_triPase PF02940.15 CDO70823.1 - 7.4e-51 173.0 0.0 9.6e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Fic PF02661.18 CDO70824.1 - 1.3e-14 54.8 0.1 4.1e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Fic/DOC family E1_dh PF00676.20 CDO70825.1 - 1.1e-85 287.3 0.0 1.3e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Spuma_A9PTase PF03539.14 CDO70825.1 - 0.22 11.7 1.0 0.42 10.7 1.0 1.4 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Myb_DNA-binding PF00249.31 CDO70825.1 - 1.5 9.1 6.7 7.7 6.8 1.5 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Syndecan PF01034.20 CDO70826.1 - 0.012 15.5 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Syndecan domain PRIMA1 PF16101.5 CDO70826.1 - 0.61 10.1 12.3 0.22 11.6 0.4 3.4 2 1 1 3 3 3 0 Proline-rich membrane anchor 1 Fe-ADH PF00465.19 CDO70828.1 - 5.9e-58 196.4 0.2 7.4e-58 196.1 0.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CDO70828.1 - 4.9e-33 114.9 0.0 5.9e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 CDO70828.1 - 2.9e-07 29.9 0.7 5.7e-06 25.7 0.7 2.5 1 1 0 1 1 1 1 3-dehydroquinate synthase MatE PF01554.18 CDO70829.1 - 6e-49 165.8 18.1 4.1e-25 88.3 3.8 2.3 2 0 0 2 2 2 2 MatE UPF0242 PF06785.11 CDO70829.1 - 0.017 15.2 0.1 0.039 14.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Arginase PF00491.21 CDO70830.1 - 3.4e-81 272.8 0.1 4.5e-81 272.4 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 CDO70830.1 - 0.081 13.1 0.3 0.16 12.2 0.0 1.5 2 0 0 2 2 2 0 UPF0489 domain SKG6 PF08693.10 CDO70831.1 - 0.00068 19.0 0.8 0.0032 16.8 0.8 2.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gly-zipper_Omp PF13488.6 CDO70831.1 - 0.0026 17.7 4.8 0.0051 16.8 4.8 1.5 1 0 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.15 CDO70831.1 - 0.0032 17.3 5.5 0.0058 16.5 5.5 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Yip1 PF04893.17 CDO70831.1 - 0.011 15.5 0.1 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 Yip1 domain Gram_pos_anchor PF00746.21 CDO70831.1 - 0.015 15.2 0.3 0.037 14.0 0.3 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Gly-zipper_YMGG PF13441.6 CDO70831.1 - 0.021 14.6 5.3 0.04 13.7 5.3 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Adeno_E3_CR2 PF02439.15 CDO70831.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Mid2 PF04478.12 CDO70833.1 - 0.0014 18.5 0.2 0.005 16.7 0.2 2.0 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor MMS1_N PF10433.9 CDO70836.1 - 1.5e-45 155.8 0.0 2.6e-44 151.7 0.0 1.9 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_S4e PF00900.20 CDO70836.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal family S4e DUF5031 PF16434.5 CDO70836.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5031) C2 PF00168.30 CDO70837.1 - 7.1e-08 32.7 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain SR-25 PF10500.9 CDO70837.1 - 0.06 12.9 14.3 0.13 11.9 14.3 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF778 PF05608.12 CDO70837.1 - 0.093 13.1 1.1 0.17 12.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) CBM32 PF18344.1 CDO70838.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding module family 32 Zip PF02535.22 CDO70839.1 - 3.5e-24 85.7 16.3 5.8e-23 81.6 16.3 2.5 1 1 0 1 1 1 1 ZIP Zinc transporter SKN1 PF03935.15 CDO70840.1 - 7.6e-202 671.2 5.2 9.4e-202 670.9 5.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Peptidase_C48 PF02902.19 CDO70841.1 - 8.2e-35 120.6 0.1 7.4e-23 81.5 0.0 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Glyco_trans_2_3 PF13632.6 CDO70842.1 - 1.6e-11 44.5 16.2 2.5e-10 40.6 12.7 3.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CDO70842.1 - 5.9e-11 42.7 0.5 1.6e-08 34.7 0.5 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 CDO70842.1 - 2.2e-07 29.9 0.0 1.2e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Chitin synthase Glyco_transf_21 PF13506.6 CDO70842.1 - 0.00021 20.8 0.6 0.036 13.5 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CDO70842.1 - 0.078 12.8 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 F-box PF00646.33 CDO70843.1 - 3.9e-08 33.0 0.3 8.9e-08 31.8 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO70843.1 - 0.00021 21.1 0.3 0.00053 19.8 0.3 1.6 1 0 0 1 1 1 1 F-box-like FAD_binding_2 PF00890.24 CDO70844.1 - 1.9e-44 152.4 1.5 1.8e-37 129.4 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 CDO70844.1 - 4.9e-07 29.5 0.0 1.2e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDO70844.1 - 7.2e-05 22.2 0.1 0.059 12.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDO70844.1 - 0.0007 18.8 3.1 0.00096 18.3 0.3 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.24 CDO70844.1 - 0.0025 17.4 3.4 0.0025 17.4 3.4 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDO70844.1 - 0.0038 17.4 0.8 0.015 15.5 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CDO70844.1 - 0.0074 15.0 0.0 0.25 10.0 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 CDO70844.1 - 0.19 10.9 0.0 1 8.6 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 CDO70845.1 - 5.5e-43 147.2 0.5 1.6e-41 142.4 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO70845.1 - 2.5e-36 125.0 0.1 5.9e-36 123.8 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO70845.1 - 1.2e-07 31.8 1.9 1.5e-07 31.5 0.5 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CDO70845.1 - 0.027 13.9 0.1 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CDO70845.1 - 0.045 13.6 1.3 0.14 12.0 0.4 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 CDO70845.1 - 0.16 11.1 0.2 0.28 10.3 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F-box-like PF12937.7 CDO70846.1 - 6.2e-11 42.0 0.1 1.7e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.7 CDO70847.1 - 0.055 14.1 1.1 0.068 13.8 1.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2785 PF10978.8 CDO70847.1 - 0.076 12.8 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) CobU PF02283.16 CDO70847.1 - 0.1 12.2 0.5 0.15 11.6 0.5 1.2 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Abhydrolase_6 PF12697.7 CDO70848.1 - 1.8e-12 48.3 3.7 2.2e-12 48.1 3.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDO70848.1 - 0.0062 16.2 0.1 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO70848.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MATH PF00917.26 CDO70849.1 - 0.0001 22.4 0.1 0.00018 21.6 0.1 1.3 1 0 0 1 1 1 1 MATH domain GRASP55_65 PF04495.14 CDO70850.1 - 1.2e-58 197.4 0.0 7.5e-42 142.9 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 CDO70850.1 - 0.00038 20.7 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CDO70850.1 - 0.0049 16.7 0.2 0.045 13.6 0.0 2.5 3 0 0 3 3 3 1 PDZ domain PPR_3 PF13812.6 CDO70851.1 - 0.022 14.8 0.0 0.11 12.6 0.0 2.2 2 1 0 2 2 2 0 Pentatricopeptide repeat domain PPR_2 PF13041.6 CDO70851.1 - 0.075 13.2 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 PPR repeat family Fungal_trans PF04082.18 CDO70852.1 - 0.017 14.2 0.1 0.048 12.7 0.1 1.8 1 1 0 1 1 1 0 Fungal specific transcription factor domain HSCB_C PF07743.13 CDO70852.1 - 0.13 12.7 0.1 0.67 10.5 0.0 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain ThiF PF00899.21 CDO70853.1 - 8.3e-23 81.0 0.1 5.4e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 ThiF family Mur_ligase_M PF08245.12 CDO70854.1 - 7.3e-07 29.4 0.0 3.5e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CDO70854.1 - 0.0072 16.6 0.0 0.033 14.4 0.0 2.2 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain RRM_1 PF00076.22 CDO70855.1 - 8.2e-51 169.7 2.6 5.5e-18 64.5 0.2 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDO70855.1 - 6.3e-13 48.4 0.1 9.1e-05 22.2 0.0 4.6 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CDO70855.1 - 2.9e-06 27.3 0.1 1.7 8.8 0.0 5.1 4 1 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDO70855.1 - 0.00013 21.9 0.0 1.7 8.7 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Suf PF05843.14 CDO70855.1 - 0.00056 20.0 2.4 0.0014 18.6 0.0 2.7 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) PHM7_cyt PF14703.6 CDO70855.1 - 0.0062 16.8 1.4 0.68 10.1 0.0 3.6 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 CDO70855.1 - 0.045 13.8 4.7 0.46 10.5 0.1 4.1 4 0 0 4 4 4 0 RNA binding motif RBFA PF02033.18 CDO70855.1 - 0.055 13.9 0.0 3.4 8.2 0.0 3.0 2 0 0 2 2 2 0 Ribosome-binding factor A Lsm_interact PF05391.11 CDO70855.1 - 0.11 12.0 1.4 0.23 11.0 1.4 1.6 1 0 0 1 1 1 0 Lsm interaction motif TPR_14 PF13428.6 CDO70855.1 - 1.2 10.2 0.0 1.2 10.2 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDO70855.1 - 3.8 8.1 11.8 4.1 8.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat UBA2_C PF16195.5 CDO70855.1 - 8.9 7.1 10.3 0.3 11.8 2.9 2.4 3 0 0 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus AAA_15 PF13175.6 CDO70857.1 - 2.6e-12 47.1 6.0 5.6e-11 42.8 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 CDO70857.1 - 2.5e-11 43.4 8.4 2.5e-11 43.4 8.4 3.7 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDO70857.1 - 2.6e-11 44.4 29.5 2.6e-11 44.4 29.5 5.2 3 2 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CDO70857.1 - 0.0003 20.5 0.1 0.0013 18.4 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CDO70857.1 - 0.00064 19.6 2.3 0.0011 18.8 0.2 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Seryl_tRNA_N PF02403.22 CDO70857.1 - 0.0051 17.0 1.9 0.0051 17.0 1.9 7.5 3 2 3 6 6 6 1 Seryl-tRNA synthetase N-terminal domain UPF0242 PF06785.11 CDO70857.1 - 0.0079 16.3 8.7 0.0079 16.3 8.7 6.5 2 2 4 6 6 6 1 Uncharacterised protein family (UPF0242) N-terminus DUF3145 PF11343.8 CDO70857.1 - 0.015 14.8 0.2 0.071 12.7 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) ABC_tran PF00005.27 CDO70857.1 - 0.11 13.0 0.0 0.11 13.0 0.0 4.0 3 2 0 3 3 3 0 ABC transporter Filament PF00038.21 CDO70857.1 - 6.9 6.2 79.4 0.0076 15.9 16.8 4.7 2 2 1 3 3 3 0 Intermediate filament protein ICL PF00463.21 CDO70858.1 - 4.6e-262 870.2 0.3 5.2e-262 870.0 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CDO70858.1 - 3.2e-09 36.6 0.0 6.6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Glycos_transf_4 PF00953.21 CDO70859.1 - 2e-18 66.9 1.9 3.5e-18 66.1 1.9 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 4 F-actin_cap_A PF01267.17 CDO70860.1 - 3.1e-100 335.0 0.0 3.5e-100 334.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit PBP_N PF17093.5 CDO70860.1 - 0.092 13.0 0.4 0.16 12.2 0.4 1.3 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus AMP-binding PF00501.28 CDO70861.1 - 6.3e-49 166.7 0.0 7.8e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDO70861.1 - 0.0017 19.3 0.8 0.004 18.1 0.8 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Eno-Rase_FAD_bd PF07055.12 CDO70861.1 - 0.14 12.6 0.1 0.35 11.3 0.1 1.6 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain AMP-binding PF00501.28 CDO70862.1 - 7.5e-06 24.8 0.0 1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme SET PF00856.28 CDO70863.1 - 1e-09 39.0 0.0 2.7e-08 34.4 0.0 2.4 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.23 CDO70863.1 - 8.8e-06 25.5 0.3 7.5e-05 22.6 0.3 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region TilS PF09179.11 CDO70863.1 - 0.00051 20.5 0.1 0.0012 19.3 0.1 1.6 1 0 0 1 1 1 1 TilS substrate binding domain MafB19-deam PF14437.6 CDO70863.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase DUF2145 PF09916.9 CDO70863.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) PLDc_2 PF13091.6 CDO70864.1 - 2.7e-13 49.9 0.0 3.7e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CDO70864.1 - 1.6e-10 40.7 1.2 0.0002 21.4 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 CDO70864.1 - 3.4e-09 36.7 0.6 1.3e-07 31.6 0.0 3.2 3 0 0 3 3 3 1 PX domain PH PF00169.29 CDO70864.1 - 0.054 14.0 0.2 0.3 11.6 0.0 2.2 2 0 0 2 2 2 0 PH domain PROCN PF08083.11 CDO70865.1 - 2e-232 771.1 9.8 4.1e-232 770.1 9.3 1.8 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CDO70865.1 - 9.9e-128 424.5 0.4 2.5e-127 423.2 0.4 1.7 2 0 0 2 2 2 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CDO70865.1 - 1.2e-87 291.9 2.3 1.2e-87 291.9 2.3 2.4 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CDO70865.1 - 2.5e-85 284.0 2.3 2.5e-85 284.0 2.3 2.8 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CDO70865.1 - 2e-73 244.8 0.1 4e-73 243.8 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 CDO70865.1 - 9.4e-47 157.3 0.5 2.2e-46 156.1 0.5 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 CDO70865.1 - 3.3e-42 143.3 0.0 7.6e-42 142.1 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 CDO70865.1 - 0.0092 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Corona_5a PF06336.11 CDO70865.1 - 0.11 12.5 0.2 0.42 10.6 0.2 2.0 1 0 0 1 1 1 0 Coronavirus 5a protein Ubie_methyltran PF01209.18 CDO70868.1 - 5.4e-78 261.5 0.0 6.7e-78 261.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CDO70868.1 - 8.9e-15 55.2 0.0 2.8e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO70868.1 - 2.3e-11 44.2 0.0 4.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO70868.1 - 2.5e-11 43.6 0.0 4.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO70868.1 - 3.6e-10 40.5 0.0 9.7e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO70868.1 - 4.4e-10 39.6 0.0 7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 CDO70868.1 - 0.035 14.1 0.0 0.14 12.2 0.0 2.1 2 1 1 3 3 3 0 Zinc-binding dehydrogenase Methyltransf_8 PF05148.15 CDO70868.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Hypothetical methyltransferase ECH_1 PF00378.20 CDO70869.1 - 2.1e-22 79.7 0.0 2.8e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDO70869.1 - 7.2e-08 32.3 0.0 8.8e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CDO70869.1 - 0.0062 16.5 0.0 3.1 7.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 Asp PF00026.23 CDO70870.1 - 1.3e-69 235.0 1.4 1.6e-69 234.8 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO70870.1 - 6.6e-09 36.2 1.4 1.1e-07 32.2 0.3 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Pkinase PF00069.25 CDO70871.1 - 1.2e-50 172.4 0.0 3.3e-50 170.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70871.1 - 2.8e-18 66.1 0.0 1.2e-17 64.0 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 CDO70871.1 - 0.007 16.0 0.6 0.035 13.7 0.1 2.2 2 1 1 3 3 3 1 RIO1 family Kinase-like PF14531.6 CDO70871.1 - 0.067 12.5 0.4 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Kinase-like MOZ_SAS PF01853.18 CDO70872.1 - 5.2e-73 244.5 0.0 7.3e-73 244.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CDO70872.1 - 5.7e-21 73.9 0.6 2.5e-20 71.8 0.1 2.3 2 0 0 2 2 2 1 MYST family zinc finger domain PHD PF00628.29 CDO70872.1 - 1.9e-17 62.9 22.1 1.9e-09 37.3 5.8 3.3 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.6 CDO70872.1 - 0.00056 19.4 12.7 0.021 14.4 1.5 3.6 3 0 0 3 3 3 2 PHD-finger zf-Sec23_Sec24 PF04810.15 CDO70872.1 - 5.5 7.1 14.3 1.6 8.8 0.0 4.1 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger Prok-RING_1 PF14446.6 CDO70872.1 - 8.5 6.4 13.2 18 5.4 1.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.6 CDO70873.1 - 0.1 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain GFA PF04828.14 CDO70874.1 - 4.2e-11 43.0 0.8 8.5e-11 42.1 0.8 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Antimicrobial_4 PF08024.11 CDO70875.1 - 0.18 11.9 0.3 0.38 10.9 0.3 1.6 1 0 0 1 1 1 0 Ant antimicrobial peptide ART PF01129.18 CDO70876.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.5 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase Urease_alpha PF00449.20 CDO70878.1 - 2.5e-55 186.0 2.5 5.5e-55 184.9 2.5 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_1 PF01979.20 CDO70878.1 - 1e-51 176.3 1.2 2.9e-49 168.2 0.1 2.3 1 1 1 2 2 2 2 Amidohydrolase family Urease_beta PF00699.20 CDO70878.1 - 1.7e-42 143.4 0.1 4.7e-42 142.0 0.1 1.8 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 CDO70878.1 - 3e-40 136.5 0.2 8.2e-40 135.1 0.2 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 CDO70878.1 - 0.00078 19.0 1.1 0.0064 16.0 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Thaumatin PF00314.17 CDO70879.1 - 1.2e-62 211.4 8.2 2.3e-61 207.2 8.2 2.5 1 1 0 1 1 1 1 Thaumatin family MFS_1 PF07690.16 CDO70881.1 - 1.5e-40 139.2 52.2 1.9e-32 112.6 25.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO70881.1 - 6e-08 32.0 17.3 8e-07 28.3 1.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 CDO70881.1 - 0.29 9.5 8.7 0.068 11.6 0.4 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 CDO70881.1 - 0.63 8.5 22.1 0.028 13.0 10.2 3.4 3 1 0 3 3 3 0 MFS/sugar transport protein BBE PF08031.12 CDO70883.1 - 7e-07 29.3 0.0 9.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 CDO70884.1 - 1.1e-07 31.7 2.7 3.8e-06 26.7 0.0 2.8 2 1 1 3 3 3 2 FAD binding domain SPT2 PF08243.11 CDO70885.1 - 4.1e-22 78.8 8.3 4.1e-22 78.8 8.3 4.4 4 1 0 4 4 4 1 SPT2 chromatin protein RRM_1 PF00076.22 CDO70886.1 - 0.00039 20.2 0.0 0.00088 19.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acyl-CoA_dh_1 PF00441.24 CDO70887.1 - 3.7e-33 114.8 0.6 5.4e-33 114.3 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDO70887.1 - 2.8e-16 59.5 1.4 3.9e-16 59.0 0.4 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CDO70887.1 - 9.3e-13 48.8 0.0 1.9e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 CDO70887.1 - 6.9e-12 45.3 0.0 1.8e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 CDO70887.1 - 2.9e-07 30.8 0.1 5.4e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SPA PF08616.10 CDO70888.1 - 4.2e-05 23.5 0.0 8.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis TOM13 PF08219.11 CDO70889.1 - 2.2e-13 50.0 0.0 5.6e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Outer membrane protein TOM13 DUF3106 PF11304.8 CDO70889.1 - 0.025 15.1 4.0 0.025 15.1 4.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) MSP1_C PF07462.11 CDO70889.1 - 0.18 10.5 1.0 0.3 9.7 1.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DEC-1_N PF04625.13 CDO70889.1 - 0.76 8.7 6.3 1.6 7.6 6.3 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Vps39_1 PF10366.9 CDO70890.1 - 1.8e-25 89.3 0.0 4.5e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 CDO70890.1 - 1.2e-12 47.9 1.0 2.5e-07 30.6 0.3 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.9 CDO70890.1 - 1.3e-09 38.4 0.3 2.9e-09 37.3 0.3 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 CDO70890.1 - 0.00015 21.5 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 CNH domain TPR_14 PF13428.6 CDO70890.1 - 0.0041 17.8 1.0 7.9 7.6 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat Cas_Csm6 PF09659.10 CDO70890.1 - 0.071 11.9 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) TPR_1 PF00515.28 CDO70890.1 - 6.1 6.8 10.3 17 5.5 1.2 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDO70890.1 - 8.8 6.7 11.7 16 5.9 1.3 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 CDO70892.1 - 5.2e-20 71.8 1.3 2e-06 28.3 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDO70892.1 - 7.4e-19 67.9 7.4 4.7e-05 23.9 0.1 6.1 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDO70892.1 - 2.6e-18 65.8 10.2 2.4e-07 30.9 0.0 5.7 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CDO70892.1 - 3.3e-12 46.3 14.2 0.45 11.1 0.0 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 CDO70892.1 - 1.1e-10 40.7 4.4 0.57 10.9 0.0 6.9 6 0 0 6 6 6 3 Ankyrin repeat Zip PF02535.22 CDO70893.1 - 0.53 9.4 6.3 0.54 9.4 6.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Methyltransf_25 PF13649.6 CDO70894.1 - 8.3e-07 29.6 0.0 0.00052 20.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CDO70894.1 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO70894.1 - 0.039 14.6 0.0 0.43 11.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain AMP_N PF05195.16 CDO70894.1 - 0.048 13.4 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Methyltransf_25 PF13649.6 CDO70895.1 - 0.00027 21.6 0.0 0.0072 17.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain CS PF04969.16 CDO70896.1 - 6.3e-06 27.1 0.1 1.2e-05 26.2 0.0 1.5 2 0 0 2 2 2 1 CS domain BC10 PF06726.12 CDO70897.1 - 3.6e-05 23.9 12.4 5.8e-05 23.2 12.4 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 WD40 PF00400.32 CDO70898.1 - 4.4e-32 109.6 3.3 3.3e-06 27.7 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.8 CDO70898.1 - 1e-07 31.0 0.8 0.004 15.9 0.0 3.9 4 0 0 4 4 4 2 Nucleoporin Nup120/160 YabA PF06156.13 CDO70898.1 - 0.18 12.4 0.8 0.39 11.4 0.8 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DUF1664 PF07889.12 CDO70898.1 - 1.4 9.0 3.1 2.7 8.1 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CDO70898.1 - 1.9 9.0 8.7 3.9 8.0 8.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Glyco_transf_49 PF13896.6 CDO70899.1 - 8.1e-65 219.3 0.1 2e-63 214.7 0.1 2.2 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_transf_18 PF15024.6 CDO70899.1 - 0.098 11.2 0.1 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 ATP11 PF06644.11 CDO70900.1 - 4e-82 276.0 0.1 4.6e-82 275.9 0.1 1.0 1 0 0 1 1 1 1 ATP11 protein DUF5333 PF17267.2 CDO70900.1 - 0.26 11.5 1.7 0.43 10.8 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5333) RHH_1 PF01402.21 CDO70900.1 - 1.1 9.3 3.8 0.49 10.4 0.2 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family DUF4551 PF15087.6 CDO70900.1 - 1.6 7.4 5.4 2.3 6.9 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NAD_binding_10 PF13460.6 CDO70901.1 - 4.2e-31 108.3 0.0 4.9e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CDO70901.1 - 1.3e-09 38.0 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CDO70901.1 - 3.5e-05 23.4 0.0 5.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO70901.1 - 0.00019 20.5 0.0 0.01 14.8 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PAC2 PF09754.9 CDO70901.1 - 0.036 14.1 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 PAC2 family LpxI_N PF17930.1 CDO70901.1 - 0.11 12.4 0.3 7.7 6.4 0.1 2.8 2 1 1 3 3 3 0 LpxI N-terminal domain GCS PF03074.16 CDO70901.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase Glyco_hydro_16 PF00722.21 CDO70902.1 - 5.7e-06 25.9 0.0 1.4e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Band_7_1 PF13421.6 CDO70902.1 - 0.094 12.4 0.1 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 SPFH domain-Band 7 family DUF296 PF03479.15 CDO70902.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.6 1 1 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain BPL_LplA_LipB PF03099.19 CDO70903.1 - 8.3e-06 25.7 0.0 1.8e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Thiolase_N PF00108.23 CDO70904.1 - 8.9e-10 38.4 0.5 1.8e-08 34.1 0.5 2.3 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDO70904.1 - 1.2e-06 28.2 0.1 4e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 CDO70904.1 - 0.00026 20.8 0.0 0.0022 17.8 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SMYLE_N PF18615.1 CDO70905.1 - 0.065 12.8 0.9 0.076 12.6 0.9 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CD34_antigen PF06365.12 CDO70906.1 - 0.023 14.3 0.2 0.17 11.4 0.1 2.1 3 0 0 3 3 3 0 CD34/Podocalyxin family TMEM154 PF15102.6 CDO70906.1 - 0.18 11.7 0.1 0.56 10.1 0.1 1.8 1 0 0 1 1 1 0 TMEM154 protein family Chlorosome_CsmC PF11098.8 CDO70907.1 - 0.048 13.7 5.2 0.056 13.4 5.2 1.1 1 0 0 1 1 1 0 Chlorosome envelope protein C Muted PF14942.6 CDO70907.1 - 0.049 14.0 0.5 0.054 13.8 0.5 1.0 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein T7SS_ESX_EspC PF10824.8 CDO70907.1 - 0.091 13.2 3.9 0.16 12.5 3.9 1.3 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm PRTP PF01366.18 CDO70907.1 - 0.1 10.6 2.8 0.11 10.5 2.8 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein YtxH PF12732.7 CDO70907.1 - 0.16 12.5 12.3 7.5 7.2 12.3 2.2 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 CDO70907.1 - 0.21 12.2 7.1 1.5 9.4 3.5 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Mobilization_B PF17511.2 CDO70907.1 - 0.23 11.9 4.7 0.26 11.6 4.4 1.3 1 1 0 1 1 1 0 Mobilization protein B LEA_4 PF02987.16 CDO70907.1 - 0.51 10.5 13.1 0.72 10.0 5.6 2.3 1 1 1 2 2 2 0 Late embryogenesis abundant protein DUF809 PF05663.11 CDO70907.1 - 3.4 7.8 5.7 5.1 7.2 5.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF809) LapA_dom PF06305.11 CDO70908.1 - 0.038 13.8 0.2 0.083 12.7 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain ORC6 PF05460.13 CDO70909.1 - 0.31 10.3 8.6 0.44 9.8 8.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) p450 PF00067.22 CDO70910.1 - 2.5e-59 201.2 0.0 3e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Utp12 PF04003.12 CDO70912.1 - 9e-26 90.3 0.2 1.6e-25 89.5 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 CDO70912.1 - 2.1e-07 31.5 2.1 0.0016 19.2 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat UTP15_C PF09384.10 CDO70912.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 UTP15 C terminal PD40 PF07676.12 CDO70912.1 - 0.2 11.7 0.4 0.86 9.6 0.2 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Pkinase PF00069.25 CDO70913.1 - 5.8e-77 258.6 0.0 8.8e-77 258.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO70913.1 - 4.6e-36 124.4 0.0 8.8e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDO70913.1 - 0.00088 18.3 0.0 0.034 13.1 0.0 2.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDO70913.1 - 0.013 14.9 0.0 0.027 13.8 0.0 1.7 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CDO70913.1 - 0.015 15.2 6.9 0.17 11.8 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family TFIIA PF03153.13 CDO70913.1 - 4.6 7.1 23.9 5.6 6.9 23.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit H2TH PF06831.14 CDO70914.1 - 1.1e-21 76.5 0.0 8.6e-21 73.7 0.0 2.0 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 CDO70914.1 - 1.1e-18 68.0 0.0 2.8e-18 66.6 0.0 1.8 1 1 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.11 CDO70914.1 - 0.00047 19.0 0.0 0.0014 17.5 0.0 1.6 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Glyco_hydro_16 PF00722.21 CDO70915.1 - 1.9e-08 34.0 0.1 0.0002 20.9 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 RIP PF00161.19 CDO70915.1 - 0.18 11.3 0.1 15 5.1 0.0 2.2 2 0 0 2 2 2 0 Ribosome inactivating protein SOG2 PF10428.9 CDO70915.1 - 9.5 5.3 23.2 1.6 7.8 5.3 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein SprT-like PF10263.9 CDO70916.1 - 8.2e-34 115.9 0.5 1.6e-33 114.9 0.5 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 CDO70916.1 - 0.0095 15.8 2.1 0.64 10.0 0.6 2.8 2 0 0 2 2 2 2 SprT-like zinc ribbon domain Glyco_hydro_16 PF00722.21 CDO70917.1 - 4.3e-06 26.3 0.0 9.6e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Arm PF00514.23 CDO70918.1 - 3e-72 236.6 28.7 5.1e-13 48.6 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CDO70918.1 - 9.4e-21 73.9 11.5 0.0023 18.4 0.3 8.1 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 CDO70918.1 - 3.4e-16 59.4 7.3 0.00025 21.4 0.3 7.6 3 2 4 8 8 8 5 HEAT repeats HEAT PF02985.22 CDO70918.1 - 4.7e-16 57.5 12.8 0.19 12.1 0.0 9.5 9 0 0 9 9 9 5 HEAT repeat Adaptin_N PF01602.20 CDO70918.1 - 2.5e-09 36.3 12.2 1.6e-05 23.7 0.1 3.0 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.13 CDO70918.1 - 4e-09 36.3 10.5 0.0029 17.1 1.9 3.7 3 1 1 4 4 4 3 Armadillo-like V-ATPase_H_N PF03224.14 CDO70918.1 - 1.2e-08 34.6 5.6 0.002 17.5 6.5 4.4 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.12 CDO70918.1 - 1.4e-08 33.4 1.1 3.5e-08 32.1 0.7 1.7 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) Cnd1 PF12717.7 CDO70918.1 - 1.2e-07 31.9 4.9 0.025 14.6 0.7 5.1 2 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 CDO70918.1 - 0.00011 22.3 1.2 28 4.9 0.1 5.2 3 1 3 6 6 6 0 V-ATPase subunit H DUF3361 PF11841.8 CDO70918.1 - 0.00012 22.0 8.3 2.1 8.3 0.0 4.0 2 1 0 3 3 3 3 Domain of unknown function (DUF3361) UNC45-central PF11701.8 CDO70918.1 - 0.016 15.1 5.4 12 5.9 0.0 3.8 3 1 1 4 4 4 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 CDO70918.1 - 0.021 15.4 0.0 1.9 9.1 0.0 3.1 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 CDO70918.1 - 0.077 13.7 11.4 59 4.8 0.2 7.2 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 CDO70918.1 - 0.27 11.3 6.1 0.31 11.1 0.2 3.7 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 CDO70918.1 - 4 7.9 5.5 31 5.0 0.6 4.0 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Abhydrolase_2 PF02230.16 CDO70919.1 - 1e-39 136.6 0.0 2e-34 119.3 0.0 2.0 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CDO70919.1 - 9.5e-06 26.4 0.9 1.1e-05 26.1 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 CDO70919.1 - 0.0017 17.9 0.0 0.03 13.9 0.0 2.4 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Esterase_phd PF10503.9 CDO70919.1 - 0.0074 15.8 0.0 0.015 14.8 0.0 1.4 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 CDO70919.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PolyA_pol PF01743.20 CDO70920.1 - 1.3e-25 90.3 0.1 2.1e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CDO70920.1 - 0.00038 20.1 0.3 0.0012 18.6 0.1 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 CDO70920.1 - 0.04 13.9 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative HMG_box PF00505.19 CDO70921.1 - 8.9e-15 54.9 0.9 1.6e-14 54.1 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO70921.1 - 0.00012 22.6 0.3 0.00021 21.8 0.3 1.4 1 0 0 1 1 1 1 HMG-box domain 5_3_exonuc_N PF02739.16 CDO70921.1 - 0.095 12.6 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF2582 PF10771.9 CDO70921.1 - 0.17 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) DEAD PF00270.29 CDO70922.1 - 3.6e-36 124.6 0.1 6.1e-36 123.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO70922.1 - 2.1e-24 86.0 0.0 5.9e-24 84.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO70922.1 - 2.2e-05 24.5 0.0 3.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.19 CDO70922.1 - 0.049 14.2 0.4 0.049 14.2 0.4 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein AAA_22 PF13401.6 CDO70922.1 - 0.11 12.7 0.1 0.33 11.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF3802 PF12290.8 CDO70922.1 - 0.17 12.4 0.1 0.39 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) CMS1 PF14617.6 CDO70922.1 - 2.9 7.2 5.7 1.3 8.3 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Mito_carr PF00153.27 CDO70923.1 - 4.3e-31 106.7 0.0 1.7e-18 66.3 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DEAD PF00270.29 CDO70924.1 - 1.6e-29 102.9 0.0 2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDO70924.1 - 6.2e-07 29.6 0.0 8.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDO70925.1 - 1.5e-25 89.7 0.0 2.3e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HATPase_c PF02518.26 CDO70926.1 - 8.8e-28 97.1 0.1 1.7e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CDO70926.1 - 4.1e-19 68.8 0.0 1.1e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 CDO70926.1 - 3.6e-14 52.6 0.0 1.7e-13 50.4 0.0 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 CDO70926.1 - 1.3e-13 51.7 1.4 2.4e-11 44.3 0.4 3.6 3 0 0 3 3 3 1 AAA ATPase domain GAF_2 PF13185.6 CDO70926.1 - 5.2e-12 46.2 0.0 1.4e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CDO70926.1 - 5.8e-08 33.4 0.0 1.5e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.17 CDO70926.1 - 1.2e-07 31.3 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDO70926.1 - 2.2e-07 30.5 0.0 5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.6 CDO70926.1 - 2.5e-06 27.9 0.0 1.4e-05 25.4 0.0 2.4 2 0 0 2 2 1 1 GAF domain NACHT PF05729.12 CDO70926.1 - 0.0013 18.7 7.3 0.0073 16.2 7.3 2.3 1 1 0 1 1 1 1 NACHT domain HATPase_c_3 PF13589.6 CDO70926.1 - 0.0047 16.7 0.0 0.023 14.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3369 PF11849.8 CDO70926.1 - 0.012 15.8 0.0 0.078 13.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3369) AAA_29 PF13555.6 CDO70926.1 - 0.068 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_12 PF13424.6 CDO70926.1 - 0.13 12.6 0.6 0.88 9.9 0.2 2.8 2 0 0 2 2 1 0 Tetratricopeptide repeat AAA_30 PF13604.6 CDO70926.1 - 0.16 11.7 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 CDO70927.1 - 4.7e-55 186.9 55.6 2.6e-43 148.3 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDO70927.1 - 3.3e-09 36.1 20.9 0.00019 20.5 0.7 3.4 2 2 1 3 3 3 3 MFS_1 like family OATP PF03137.20 CDO70927.1 - 6.1e-07 28.1 4.6 0.0021 16.4 0.0 2.6 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Acatn PF13000.7 CDO70928.1 - 2.1e-145 485.4 23.2 1.5e-68 231.7 16.5 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 GYF PF02213.16 CDO70929.1 - 8.5e-16 57.4 0.6 2.1e-15 56.1 0.6 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CDO70929.1 - 0.004 16.9 0.1 0.013 15.3 0.1 2.0 1 0 0 1 1 1 1 GYF domain 2 Mod_r PF07200.13 CDO70930.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.9 CDO70931.1 - 9.4e-13 47.9 0.2 2.8e-12 46.4 0.2 1.9 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 SPX PF03105.19 CDO70931.1 - 0.94 9.3 7.7 3.7 7.4 0.6 2.3 2 0 0 2 2 2 0 SPX domain PUF PF00806.19 CDO70932.1 - 6.6e-54 176.7 9.9 1.1e-07 31.1 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat SET PF00856.28 CDO70933.1 - 3.1e-18 66.7 0.0 2.4e-17 63.8 0.0 2.2 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 CDO70933.1 - 0.011 16.4 3.5 0.32 11.7 1.1 2.6 2 1 0 2 2 2 0 Pre-SET motif HMG_box PF00505.19 CDO70934.1 - 6.3e-13 48.9 0.6 1e-12 48.3 0.6 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO70934.1 - 0.0002 21.9 0.1 0.00037 21.0 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain DHO_dh PF01180.21 CDO70935.1 - 0.0013 18.0 0.0 0.78 8.9 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase TRAPP PF04051.16 CDO70936.1 - 7.4e-44 149.0 0.0 8.8e-44 148.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component BCNT PF07572.12 CDO70938.1 - 8.9e-17 60.9 0.1 1.3e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 Bucentaur or craniofacial development NAM-associated PF14303.6 CDO70938.1 - 0.59 10.8 5.0 0.85 10.3 5.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Cullin PF00888.22 CDO70939.1 - 9.4e-05 21.2 0.0 0.00011 21.0 0.0 1.1 1 0 0 1 1 1 1 Cullin family Med9 PF07544.13 CDO70940.1 - 5.7e-07 29.5 0.2 7.2e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 dbPDZ_assoc PF16610.5 CDO70940.1 - 0.072 13.3 0.4 0.61 10.3 0.0 2.2 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 YtxH PF12732.7 CDO70940.1 - 0.29 11.7 3.6 5.8 7.5 0.5 2.2 1 1 0 2 2 2 0 YtxH-like protein Herpes_TAF50 PF03326.13 CDO70941.1 - 0.013 14.2 7.4 0.013 14.1 7.4 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) CbiG_C PF01890.16 CDO70942.1 - 0.27 11.8 0.7 0.45 11.1 0.7 1.3 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus PSP1 PF04468.12 CDO70944.1 - 1e-30 105.8 2.7 1.7e-30 105.1 2.7 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rgp1 PF08737.10 CDO70945.1 - 2.3e-48 165.4 0.0 1.5e-47 162.7 0.0 2.1 2 1 0 2 2 2 1 Rgp1 Arrestin_C PF02752.22 CDO70945.1 - 0.00087 19.8 0.0 2.6 8.5 0.0 3.3 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CDO70945.1 - 0.1 12.7 0.0 2.8 8.0 0.0 2.5 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain TrkH PF02386.16 CDO70946.1 - 1.1e-83 281.5 4.6 2.2e-67 227.6 0.1 2.0 2 0 0 2 2 2 2 Cation transport protein PCI PF01399.27 CDO70947.1 - 4e-06 27.3 3.1 5.2e-06 26.9 0.5 2.1 2 0 0 2 2 2 1 PCI domain DSBA PF01323.20 CDO70947.1 - 0.023 14.4 2.4 0.039 13.7 2.4 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain DUF3452 PF11934.8 CDO70947.1 - 0.026 14.1 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Peptidase_S10 PF00450.22 CDO70948.1 - 3.3e-50 171.7 0.3 1.2e-49 169.8 0.3 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase PRK PF00485.18 CDO70949.1 - 0.00015 21.6 0.1 0.0087 15.8 0.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CDO70949.1 - 0.0015 19.1 0.0 0.0037 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CDO70949.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CDO70949.1 - 0.022 15.1 0.1 0.034 14.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CDO70949.1 - 0.035 14.2 0.1 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase KTI12 PF08433.10 CDO70949.1 - 0.039 13.4 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 CDO70949.1 - 0.043 13.0 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Phage_CI_C PF16452.5 CDO70949.1 - 0.048 14.0 0.0 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage CI repressor C-terminal domain AAA_33 PF13671.6 CDO70949.1 - 0.058 13.6 0.3 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CDO70949.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin zf-C2H2 PF00096.26 CDO70951.1 - 1.3e-07 31.7 10.0 0.0037 17.7 6.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO70951.1 - 5.2e-06 26.7 11.8 2.7e-05 24.4 0.2 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDO70951.1 - 0.0076 17.0 11.6 0.13 13.1 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CDO70951.1 - 0.025 14.5 1.4 0.025 14.5 1.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 CDO70951.1 - 0.25 11.1 6.9 0.27 11.0 0.1 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HE PF16278.5 CDO70951.1 - 0.7 10.4 7.6 0.41 11.1 2.9 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger BAH PF01426.18 CDO70952.1 - 2.8e-11 43.3 0.0 6.7e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 BAH domain Bromodomain PF00439.25 CDO70952.1 - 3.2e-10 39.9 0.5 3.5e-05 23.8 0.2 3.5 2 1 0 2 2 2 2 Bromodomain SOG2 PF10428.9 CDO70952.1 - 8.8 5.4 10.8 1.6 7.8 3.1 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein A_deaminase PF00962.22 CDO70953.1 - 4.3e-13 49.3 0.2 4.9e-12 45.8 0.2 2.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF3752 PF12572.8 CDO70954.1 - 1.5e-31 110.0 6.0 1.5e-31 110.0 6.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3752) adh_short_C2 PF13561.6 CDO70955.1 - 9.7e-50 169.3 2.9 1.2e-47 162.5 2.9 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO70955.1 - 8.4e-45 152.6 0.8 1e-44 152.3 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO70955.1 - 9e-15 55.0 0.1 1.3e-14 54.6 0.1 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 CDO70955.1 - 0.011 15.8 0.3 0.02 15.0 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 CDO70955.1 - 0.013 15.4 0.2 0.02 14.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain G-alpha PF00503.20 CDO70956.1 - 4.7e-88 295.7 0.8 5.5e-67 226.4 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.21 CDO70956.1 - 7.5e-11 41.8 0.7 1.5e-05 24.6 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_15 PF13175.6 CDO70956.1 - 0.0055 16.5 0.1 0.0093 15.7 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 CDO70956.1 - 0.014 15.4 0.1 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CDO70956.1 - 0.04 14.4 0.5 0.12 12.9 0.3 1.8 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 CDO70956.1 - 0.059 13.6 0.1 1.3 9.2 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CDO70956.1 - 0.065 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain COOH-NH2_lig PF14395.6 CDO70956.1 - 0.11 11.6 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 GTP_EFTU PF00009.27 CDO70956.1 - 0.13 11.7 0.7 17 4.9 0.0 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CDO70956.1 - 0.15 11.4 0.7 6 6.1 0.0 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Cullin PF00888.22 CDO70959.1 - 1.8e-106 357.2 0.0 2.5e-60 204.8 0.0 2.3 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 CDO70959.1 - 1.2e-23 82.9 0.7 3.1e-23 81.6 0.7 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF515 PF04415.12 CDO70959.1 - 0.0062 15.0 0.5 0.013 13.9 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF515) MSA-2c PF12238.8 CDO70959.1 - 0.021 14.8 0.4 0.059 13.4 0.4 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c WAC_Acf1_DNA_bd PF10537.9 CDO70959.1 - 0.18 12.4 1.2 38 4.9 0.4 2.9 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal SPO22 PF08631.10 CDO70960.1 - 3.3e-44 151.4 15.3 1.8e-41 142.5 2.7 4.7 4 1 1 5 5 5 3 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 CDO70960.1 - 0.0019 18.5 4.5 0.075 13.3 0.1 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDO70960.1 - 4.8 7.8 7.7 2.2 8.8 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyclin PF08613.11 CDO70961.1 - 8.1e-15 55.5 0.1 2.1e-14 54.2 0.1 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CDO70961.1 - 9.9e-10 38.3 0.0 2.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain SUIM_assoc PF16619.5 CDO70961.1 - 0.0064 16.5 0.0 0.087 12.9 0.0 3.0 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Chs7 PF12271.8 CDO70962.1 - 3.6e-115 384.3 20.8 4.1e-115 384.1 20.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone His_Phos_2 PF00328.22 CDO70963.1 - 2.8e-46 158.6 0.0 3.5e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) tRNA-synt_1c PF00749.21 CDO70964.1 - 3e-85 285.9 0.0 4.4e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain zf-UBR PF02207.20 CDO70965.1 - 3.6e-17 62.3 16.4 3.6e-17 62.3 16.4 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CDO70965.1 - 2.7e-10 39.9 0.0 6.7e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DinB_2 PF12867.7 CDO70965.1 - 0.11 13.0 0.3 0.83 10.2 0.0 2.6 2 1 0 2 2 2 0 DinB superfamily TRAPP PF04051.16 CDO70966.1 - 2.4e-26 92.2 0.0 4.1e-26 91.4 0.0 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component ANAPC4_WD40 PF12894.7 CDO70967.1 - 5.5e-06 26.6 0.0 0.073 13.4 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDO70967.1 - 0.0058 17.5 6.0 20 6.2 0.0 5.5 4 2 1 5 5 5 2 WD domain, G-beta repeat Glyco_transf_25 PF01755.17 CDO70968.1 - 2.9e-05 24.0 0.0 0.00041 20.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) zf-CCHC PF00098.23 CDO70969.1 - 0.0014 18.6 2.1 0.0032 17.5 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CDO70969.1 - 0.041 13.6 3.4 0.085 12.6 3.4 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Gly_transf_sug PF04488.15 CDO70970.1 - 4.1e-06 27.3 0.0 6.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CDO70970.1 - 0.011 15.1 0.2 0.014 14.8 0.2 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DFP PF04127.15 CDO70972.1 - 3.1e-15 56.5 0.0 9.5e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein HAD PF12710.7 CDO70972.1 - 0.15 12.4 0.0 3.6 7.9 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Abhydrolase_1 PF00561.20 CDO70974.1 - 6.5e-21 75.1 0.0 1e-19 71.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO70974.1 - 4.1e-16 60.3 13.1 3e-15 57.4 13.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO70974.1 - 4.7e-09 35.9 0.0 1.5e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 CDO70974.1 - 0.025 13.6 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase XPG_I PF00867.18 CDO70975.1 - 2.8e-24 85.3 0.0 5.6e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDO70975.1 - 5.2e-07 30.1 0.0 9.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 CDO70975.1 - 7.9e-05 23.2 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 CDO70975.1 - 0.00051 19.6 2.0 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing TPR_1 PF00515.28 CDO70975.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDO70975.1 - 0.024 14.7 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDO70975.1 - 0.1 12.5 0.1 0.32 10.9 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDO70975.1 - 0.18 12.1 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Gly-zipper_OmpA PF13436.6 CDO70975.1 - 1 9.2 5.1 2.3 8.1 5.1 1.6 1 0 0 1 1 1 0 Glycine-zipper domain zf-C2H2 PF00096.26 CDO70976.1 - 0.00011 22.4 0.8 0.00028 21.2 0.8 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO70976.1 - 0.037 14.9 0.4 0.12 13.3 0.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger PIG-P PF08510.12 CDO70977.1 - 3.4e-27 94.7 2.6 4.1e-27 94.5 2.6 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 CDO70977.1 - 0.033 14.5 8.9 0.077 13.3 8.9 1.6 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Serine_protease PF18405.1 CDO70978.1 - 0.042 13.0 0.1 0.055 12.6 0.1 1.1 1 0 0 1 1 1 0 Gammaproteobacterial serine protease 5-FTHF_cyc-lig PF01812.20 CDO70978.1 - 0.045 13.6 0.0 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family Rad51 PF08423.11 CDO70979.1 - 7.4e-07 28.7 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CDO70979.1 - 1.1e-05 25.0 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CDO70979.1 - 2e-05 24.1 0.1 0.00031 20.2 0.0 2.4 1 1 1 3 3 3 1 KaiC DnaB_C PF03796.15 CDO70979.1 - 0.0029 17.0 0.0 0.0064 15.8 0.0 1.5 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 CDO70979.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CDO70979.1 - 0.032 13.8 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 CDO70979.1 - 0.071 12.2 0.3 7.7 5.5 0.0 2.1 1 1 1 2 2 2 0 PAXNEB protein RRM_1 PF00076.22 CDO70980.1 - 1.4e-27 95.3 0.0 2.1e-11 43.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDO70980.1 - 9.9e-07 28.5 0.0 0.084 12.8 0.0 3.8 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CDO70980.1 - 0.00038 20.0 0.0 0.66 9.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDO70980.1 - 0.036 14.1 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CDO70980.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif ABC_tran PF00005.27 CDO70981.1 - 4.6e-31 108.2 0.1 1.6e-16 61.1 0.0 3.2 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 CDO70981.1 - 2.4e-14 52.8 5.4 5.9e-14 51.6 5.4 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 CDO70981.1 - 6.7e-11 42.5 3.5 0.37 10.6 1.4 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDO70981.1 - 9.4e-11 41.6 2.4 0.0053 16.2 0.1 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 CDO70981.1 - 6.9e-07 28.8 3.2 6.9e-07 28.8 3.2 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 CDO70981.1 - 1.1e-05 25.4 0.1 0.088 12.7 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA PF00004.29 CDO70981.1 - 1.3e-05 25.7 0.1 0.12 12.9 0.1 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDO70981.1 - 2.4e-05 24.8 0.0 0.24 11.7 0.0 2.6 2 2 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 CDO70981.1 - 7.8e-05 22.6 0.9 0.023 14.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 CDO70981.1 - 0.00011 22.1 0.1 0.29 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CDO70981.1 - 0.00016 21.9 0.0 0.067 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDO70981.1 - 0.0002 21.7 0.1 0.22 11.9 0.0 2.8 3 0 0 3 3 2 1 RNA helicase Fer4_6 PF12837.7 CDO70981.1 - 0.00055 19.9 2.2 0.00055 19.9 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.15 CDO70981.1 - 0.00066 19.7 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 CDO70981.1 - 0.00069 19.2 0.4 0.016 14.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region SRP54 PF00448.22 CDO70981.1 - 0.0011 18.7 1.8 0.2 11.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CDO70981.1 - 0.0016 18.6 0.0 0.85 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CDO70981.1 - 0.0019 17.9 0.1 0.48 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDO70981.1 - 0.0022 17.7 1.4 1.5 8.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fer4_7 PF12838.7 CDO70981.1 - 0.0024 18.4 0.5 0.0024 18.4 0.5 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDO70981.1 - 0.0029 17.7 14.8 0.0042 17.2 1.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 CDO70981.1 - 0.004 17.2 0.6 0.004 17.2 0.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 CDO70981.1 - 0.006 16.7 11.8 0.011 15.8 11.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NB-ARC PF00931.22 CDO70981.1 - 0.006 15.8 0.0 0.3 10.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Fer4_9 PF13187.6 CDO70981.1 - 0.0066 16.6 11.5 0.014 15.5 11.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 CDO70981.1 - 0.0071 16.3 0.1 0.26 11.3 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 CDO70981.1 - 0.012 15.3 0.1 4.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase AAA_18 PF13238.6 CDO70981.1 - 0.012 16.1 0.1 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDO70981.1 - 0.014 15.7 0.2 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDO70981.1 - 0.023 14.7 1.8 0.73 9.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Fer4_16 PF13484.6 CDO70981.1 - 0.025 15.5 0.3 0.025 15.5 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain SbcCD_C PF13558.6 CDO70981.1 - 0.03 14.6 0.0 5.2 7.4 0.0 2.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CDO70981.1 - 0.031 14.0 0.2 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CDO70981.1 - 0.031 13.5 0.0 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Roc PF08477.13 CDO70981.1 - 0.037 14.3 0.7 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 CDO70981.1 - 0.044 12.4 0.1 0.79 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CDO70981.1 - 0.049 13.7 0.2 11 6.1 0.0 3.1 3 1 0 3 3 2 0 AAA domain VirE PF05272.11 CDO70981.1 - 0.057 13.1 0.0 5.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_8 PF13183.6 CDO70981.1 - 0.12 12.9 0.1 0.12 12.9 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain CLP1_P PF16575.5 CDO70981.1 - 0.13 12.1 0.2 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 CDO70981.1 - 0.15 11.3 0.1 3.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 CDO70981.1 - 0.21 12.0 6.9 0.39 11.2 0.2 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CDO70981.1 - 0.24 11.5 0.5 29 4.8 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CDO70981.1 - 0.24 11.3 2.7 19 5.1 0.0 3.5 4 0 0 4 4 3 0 NTPase Fer4_4 PF12800.7 CDO70981.1 - 0.39 11.3 12.3 0.12 13.0 1.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 CDO70981.1 - 8.2 7.1 12.4 0.097 13.2 1.2 2.4 1 1 3 4 4 2 0 4Fe-4S dicluster domain UQ_con PF00179.26 CDO70982.1 - 2.9e-53 179.3 0.0 3.2e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDO70982.1 - 0.0044 17.3 0.0 0.0051 17.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CDO70982.1 - 0.005 16.5 0.0 0.006 16.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CDO70982.1 - 0.035 14.0 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain PIG-S PF10510.9 CDO70983.1 - 2.8e-108 363.0 0.5 3.3e-108 362.8 0.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Myb_DNA-binding PF00249.31 CDO70984.1 - 4.8e-17 61.9 0.0 5.6e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDO70984.1 - 3.5e-10 40.0 0.0 0.00075 19.7 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CDO70984.1 - 2.3e-08 33.8 0.1 0.0002 21.2 0.0 2.6 2 0 0 2 2 2 2 Myb DNA-binding like Nop16 PF09420.10 CDO70984.1 - 0.054 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Rotamase_3 PF13616.6 CDO70985.1 - 2.6e-05 24.8 1.7 3.4e-05 24.4 0.6 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 CDO70985.1 - 0.017 16.1 0.7 0.017 16.1 0.7 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain AMP-binding PF00501.28 CDO70986.1 - 2.9e-24 85.5 0.0 3.6e-23 81.8 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 CDO70986.1 - 0.0045 15.9 0.0 0.0085 15.0 0.0 1.4 1 0 0 1 1 1 1 GH3 auxin-responsive promoter PCMT PF01135.19 CDO70988.1 - 1.2e-70 237.5 0.0 1.5e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CDO70988.1 - 1.5e-05 24.9 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO70988.1 - 0.00022 21.1 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDO70988.1 - 0.00026 21.0 0.0 0.00039 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO70988.1 - 0.00039 21.1 0.0 0.00083 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO70988.1 - 0.0044 17.6 0.0 0.009 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CDO70988.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 CDO70988.1 - 0.03 15.3 0.0 0.21 12.6 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain MTS PF05175.14 CDO70988.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PPTA PF01239.22 CDO70989.1 - 5.1e-43 143.6 13.2 3.8e-09 36.0 1.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat RRM_1 PF00076.22 CDO70990.1 - 2.2e-14 53.0 0.0 3.3e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CDO70990.1 - 2.3e-08 34.5 0.1 2.3e-08 34.5 0.1 2.6 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 CDO70990.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RNA_pol_3_Rpc31 PF11705.8 CDO70991.1 - 7.2e-27 95.1 6.1 1.1e-26 94.6 6.1 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 AF-4 PF05110.13 CDO70992.1 - 0.24 9.4 1.4 0.3 9.1 1.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein p450 PF00067.22 CDO70993.1 - 1.5e-65 221.8 0.0 3.1e-65 220.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 CDO70994.1 - 1.5e-19 70.2 0.0 4.7e-13 49.0 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO70994.1 - 2.4e-14 53.4 0.0 4.7e-10 39.4 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO70995.1 - 6.2e-31 107.4 0.0 3.4e-30 105.0 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO70995.1 - 1.9e-18 66.9 0.0 3.6e-18 66.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CDO70995.1 - 0.00036 20.5 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CDO70995.1 - 0.0053 16.7 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 KR domain GMC_oxred_C PF05199.13 CDO70997.1 - 2e-37 128.9 0.0 2.9e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CDO70997.1 - 7.9e-09 35.3 0.0 0.0017 17.8 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase TMEM213 PF15192.6 CDO70997.1 - 0.022 14.7 0.8 0.035 14.0 0.2 1.6 2 0 0 2 2 2 0 TMEM213 family TFIIB PF00382.19 CDO70998.1 - 4.5e-38 129.1 1.1 5.6e-19 68.0 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CDO70998.1 - 2.3e-29 101.7 14.2 1.1e-28 99.5 4.9 2.6 2 0 0 2 2 2 2 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CDO70998.1 - 2e-08 33.6 5.1 4.5e-08 32.5 5.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 CDO70998.1 - 2.7e-06 27.1 1.2 0.016 15.0 0.4 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain DZR PF12773.7 CDO70998.1 - 0.025 14.6 0.3 0.051 13.6 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon RVT_1 PF00078.27 CDO70999.1 - 1.5e-24 86.8 0.0 2.1e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO70999.1 - 1.1e-09 38.1 0.0 4.7e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDO70999.1 - 1e-06 28.4 1.5 1.7e-05 24.4 1.4 2.8 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.24 CDO70999.1 - 0.0038 17.4 0.0 0.0061 16.7 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_2 PF07727.14 CDO71000.1 - 6.2e-62 209.4 0.0 9.1e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO71000.1 - 4.9e-19 68.7 0.4 1.1e-18 67.6 0.4 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO71000.1 - 1.7e-11 43.9 0.0 3.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO71000.1 - 5.1e-06 26.2 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 CDO71000.1 - 0.0038 17.2 3.0 0.0074 16.3 3.0 1.4 1 0 0 1 1 1 1 Zinc knuckle rhaM PF05336.13 CDO71000.1 - 0.035 14.2 0.2 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 L-rhamnose mutarotase rve_3 PF13683.6 CDO71000.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain SHIPPO-rpt PF07004.12 CDO71001.1 - 0.19 12.7 2.2 0.83 10.7 2.2 2.2 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat Pox_Ag35 PF03286.14 CDO71001.1 - 0.24 11.1 4.9 0.46 10.2 4.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 CDO71001.1 - 0.53 9.5 11.9 0.83 8.9 11.9 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 CDO71001.1 - 9.2 6.3 10.2 17 5.4 10.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal E1-E2_ATPase PF00122.20 CDO71002.1 - 1.6e-49 167.8 0.0 1.6e-49 167.8 0.0 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 CDO71002.1 - 4.6e-17 63.0 1.7 4.6e-17 63.0 1.7 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDO71002.1 - 5.6e-14 51.6 0.1 1.4e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDO71002.1 - 4e-05 23.5 0.0 0.00015 21.6 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDO71002.1 - 0.0077 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) PGA2 PF07543.12 CDO71003.1 - 3 7.8 5.2 1.9 8.5 3.5 1.5 1 1 1 2 2 2 0 Protein trafficking PGA2 DUF1996 PF09362.10 CDO71004.1 - 4.4e-65 219.9 1.1 2.3e-64 217.6 1.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 CDO71004.1 - 0.00037 20.6 3.4 0.00085 19.5 3.4 1.6 1 0 0 1 1 1 1 WSC domain Transket_pyr PF02779.24 CDO71005.1 - 2.6e-45 154.3 0.0 7.3e-45 152.8 0.0 1.7 2 1 0 2 2 2 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CDO71005.1 - 5.5e-45 152.8 0.0 8.7e-45 152.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 CDO71005.1 - 1.1e-24 86.9 0.0 2.5e-24 85.8 0.0 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component Aldo_ket_red PF00248.21 CDO71006.1 - 4.7e-44 150.7 0.0 2.2e-42 145.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Phage_P2_GpU PF06995.11 CDO71006.1 - 0.19 11.3 0.0 23 4.6 0.0 2.2 2 0 0 2 2 2 0 Phage P2 GpU HAD PF12710.7 CDO71007.1 - 1.9e-17 64.3 0.0 3.1e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CDO71007.1 - 5.9e-06 26.0 0.0 8.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 CDO71007.1 - 0.013 15.8 0.0 0.032 14.5 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.12 CDO71007.1 - 0.047 14.0 0.1 12 6.3 0.0 2.9 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Put_Phosphatase PF06888.12 CDO71007.1 - 0.065 12.6 0.0 0.35 10.2 0.0 2.1 3 0 0 3 3 3 0 Putative Phosphatase DUF3148 PF11347.8 CDO71007.1 - 0.091 12.5 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) DUF1996 PF09362.10 CDO71008.1 - 1.2e-71 241.5 0.1 2.6e-71 240.3 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 CDO71008.1 - 1.4e-11 44.4 7.4 3.4e-11 43.2 7.4 1.6 1 0 0 1 1 1 1 WSC domain Ribosomal_S6e PF01092.19 CDO71009.1 - 7.9e-60 200.3 0.1 1.9e-59 199.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e MKLP1_Arf_bdg PF16540.5 CDO71009.1 - 0.6 10.2 4.3 0.66 10.1 1.5 2.1 2 0 0 2 2 2 0 Arf6-interacting domain of mitotic kinesin-like protein 1 Ribosomal_S13_N PF08069.12 CDO71010.1 - 1.3e-31 108.4 0.1 2.5e-31 107.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CDO71010.1 - 1.9e-14 53.6 0.5 2.5e-14 53.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 UPF0220 PF05255.11 CDO71011.1 - 8.3e-52 175.1 0.0 1e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4448 PF14610.6 CDO71012.1 - 0.0012 18.6 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 CDO71012.1 - 0.0022 18.7 0.1 0.0032 18.2 0.1 1.3 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Kelch_6 PF13964.6 CDO71013.1 - 6.9e-18 64.2 8.2 0.001 19.3 0.0 6.9 4 2 2 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CDO71013.1 - 4.2e-15 55.5 8.1 0.011 15.8 0.1 6.7 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDO71013.1 - 2.3e-14 53.0 11.0 0.006 16.6 0.1 6.2 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 CDO71013.1 - 3.7e-13 48.8 5.2 9.9e-05 21.8 0.0 6.1 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 CDO71013.1 - 4.8e-09 36.3 10.6 0.29 11.5 0.0 6.6 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.15 CDO71013.1 - 1.3e-06 28.2 3.9 1.2 9.3 0.2 6.1 5 1 0 5 5 5 1 Kelch motif zf-MYND PF01753.18 CDO71013.1 - 0.00049 20.1 13.7 0.0018 18.3 13.7 2.1 1 0 0 1 1 1 1 MYND finger RepA_N PF06970.11 CDO71013.1 - 0.042 13.8 0.2 7.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus DUF1572 PF07609.11 CDO71013.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) zf-C6H2 PF15801.5 CDO71013.1 - 0.66 10.3 10.5 2.2 8.6 10.5 2.0 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding HMG_box PF00505.19 CDO71015.1 - 2.4e-08 34.2 10.3 1.1e-07 32.2 10.3 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO71015.1 - 3.5e-08 33.9 6.4 8.2e-08 32.7 6.4 1.6 1 0 0 1 1 1 1 HMG-box domain HhH-GPD PF00730.25 CDO71016.1 - 1.3e-10 41.6 0.0 3.3e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CDO71016.1 - 0.025 14.4 0.0 0.096 12.6 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif HMG_box PF00505.19 CDO71018.1 - 2.1e-11 44.0 0.1 4.7e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO71018.1 - 0.027 15.0 0.0 0.062 13.9 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain Thioredoxin PF00085.20 CDO71019.1 - 7.3e-57 189.7 0.0 4.7e-28 97.2 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 CDO71019.1 - 2.3e-25 89.3 1.2 5e-25 88.2 1.2 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 CDO71019.1 - 3.5e-18 66.0 0.0 2.1e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CDO71019.1 - 3.1e-16 59.6 0.0 6.8e-07 28.9 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 CDO71019.1 - 1.2e-10 41.6 0.0 0.00053 19.9 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDO71019.1 - 5.7e-10 39.3 0.0 0.00043 20.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CDO71019.1 - 1.1e-09 38.5 0.0 0.01 16.2 0.0 3.7 2 2 2 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 CDO71019.1 - 1.9e-08 34.3 0.0 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 CDO71019.1 - 3.2e-06 26.9 0.2 0.027 14.2 0.0 2.3 2 0 0 2 2 2 2 Redoxin TraF PF13728.6 CDO71019.1 - 4.2e-05 23.5 0.0 0.21 11.4 0.0 2.5 3 0 0 3 3 3 2 F plasmid transfer operon protein Glutaredoxin PF00462.24 CDO71019.1 - 0.00035 20.7 0.1 0.027 14.7 0.0 2.8 2 0 0 2 2 2 1 Glutaredoxin HyaE PF07449.11 CDO71019.1 - 0.00072 19.5 0.0 0.42 10.6 0.0 2.4 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 CDO71019.1 - 0.00097 18.9 0.1 0.57 10.0 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 CDO71019.1 - 0.0045 17.0 0.0 0.42 10.7 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain Jnk-SapK_ap_N PF09744.9 CDO71019.1 - 0.0088 16.3 1.2 0.016 15.4 1.2 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Thioredoxin_4 PF13462.6 CDO71019.1 - 0.039 14.1 0.5 14 5.8 0.1 3.1 2 1 1 3 3 3 0 Thioredoxin GAS PF13851.6 CDO71019.1 - 0.055 12.8 0.6 0.084 12.2 0.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DDE_Tnp_1_2 PF13586.6 CDO71019.1 - 0.061 13.7 0.0 6.7 7.2 0.0 3.2 3 0 0 3 3 3 0 Transposase DDE domain DUF953 PF06110.11 CDO71019.1 - 0.094 12.3 0.2 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_5 PF13743.6 CDO71019.1 - 0.17 11.5 0.1 11 5.6 0.0 3.4 3 1 1 4 4 4 0 Thioredoxin adh_short_C2 PF13561.6 CDO71020.1 - 3.2e-51 174.2 0.0 4e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO71020.1 - 2.4e-47 160.9 0.0 3e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO71020.1 - 5e-06 26.5 0.0 6.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 KR domain MM_CoA_mutase PF01642.22 CDO71020.1 - 0.0015 17.1 0.1 0.0022 16.7 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase THF_DHG_CYH_C PF02882.19 CDO71020.1 - 0.0017 17.7 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 CDO71020.1 - 0.015 15.1 0.4 1 9.1 0.1 2.8 2 1 1 3 3 3 0 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.10 CDO71020.1 - 0.024 14.0 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) OTCace PF00185.24 CDO71020.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain tRNA-synt_1d PF00750.19 CDO71021.1 - 6.2e-103 344.4 5.0 8.3e-103 344.0 5.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CDO71021.1 - 4.2e-22 78.6 0.0 9.5e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain HemN_C PF06969.16 CDO71021.1 - 0.0011 19.0 0.1 0.0055 16.8 0.0 2.2 2 0 0 2 2 2 1 HemN C-terminal domain DUF4880 PF16220.5 CDO71021.1 - 0.17 11.8 3.7 0.4 10.6 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) MIOX PF05153.15 CDO71022.1 - 2.7e-128 426.8 2.1 4.2e-128 426.2 2.1 1.3 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 CDO71022.1 - 0.00031 21.0 0.0 0.014 15.7 0.0 2.5 2 0 0 2 2 2 1 HD domain Metallophos PF00149.28 CDO71023.1 - 1.3e-11 45.4 0.5 1.8e-11 44.9 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDO71023.1 - 5.9e-06 26.6 0.0 3.8e-05 23.9 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain HMG_box PF00505.19 CDO71024.1 - 1.3e-12 47.9 0.2 2.7e-12 46.9 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO71024.1 - 0.0005 20.6 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain AA_permease_2 PF13520.6 CDO71025.1 - 1.3e-78 264.7 37.5 1.7e-78 264.4 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CDO71026.1 - 7.7e-74 249.0 38.0 9.2e-74 248.8 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.32 CDO71027.1 - 4.1e-18 65.4 9.6 2e-07 31.5 0.2 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO71027.1 - 8.1e-07 29.3 0.0 0.02 15.1 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDO71027.1 - 0.11 12.4 0.0 2.9 7.7 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Peptidase_C14 PF00656.22 CDO71029.1 - 3e-22 79.8 0.0 5.8e-22 78.8 0.0 1.5 1 1 0 1 1 1 1 Caspase domain DUF5129 PF17173.4 CDO71031.1 - 0.034 13.3 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Herpes_ORF11 PF04797.13 CDO71032.1 - 0.22 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein Cellulase PF00150.18 CDO71033.1 - 2.7e-15 56.5 0.0 2.2e-13 50.3 0.0 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.7 CDO71034.1 - 6.2e-09 35.6 0.6 2e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like SlyX PF04102.12 CDO71034.1 - 0.17 12.5 0.3 0.56 10.9 0.3 1.8 1 0 0 1 1 1 0 SlyX DNApol_Exo PF18136.1 CDO71037.1 - 1.3e-103 346.1 0.1 2.6e-103 345.1 0.1 1.5 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CDO71037.1 - 3.7e-49 167.8 0.0 7.3e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A Vpu PF00558.19 CDO71037.1 - 0.026 14.3 2.0 0.064 13.0 2.0 1.6 1 0 0 1 1 1 0 Vpu protein DUF2026 PF09641.10 CDO71037.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) PilJ PF13675.6 CDO71037.1 - 5.3 7.1 8.0 1.2 9.2 0.2 3.6 5 0 0 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term COesterase PF00135.28 CDO71038.1 - 2.6e-45 155.3 0.0 4.7e-45 154.4 0.0 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDO71038.1 - 0.0015 18.4 0.1 0.0031 17.4 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Perilipin PF03036.16 CDO71039.1 - 4.6e-13 48.9 10.4 7.4e-11 41.7 0.0 3.0 2 1 0 2 2 2 2 Perilipin family Apolipoprotein PF01442.18 CDO71039.1 - 1.6e-06 28.2 10.9 0.0017 18.3 3.7 3.2 2 2 1 3 3 3 2 Apolipoprotein A1/A4/E domain Prominin PF05478.11 CDO71039.1 - 0.002 16.2 4.6 0.0033 15.5 4.6 1.2 1 0 0 1 1 1 1 Prominin Gp-FAR-1 PF05823.12 CDO71039.1 - 0.0071 16.7 1.2 0.1 13.0 0.0 2.6 2 1 1 3 3 3 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GAS PF13851.6 CDO71039.1 - 0.046 13.1 1.4 0.074 12.4 0.8 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ArsR PF09824.9 CDO71039.1 - 0.049 13.2 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 ArsR transcriptional regulator PI_PP_I PF18363.1 CDO71039.1 - 0.14 12.3 1.0 28 5.0 0.4 2.9 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF4088 PF13317.6 CDO71039.1 - 0.22 11.1 2.6 0.49 9.9 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4088) Phasin PF05597.11 CDO71039.1 - 0.24 11.4 3.8 5 7.1 0.3 3.1 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Syntaxin_2 PF14523.6 CDO71039.1 - 2 8.8 5.6 4.1 7.8 1.5 2.6 1 1 1 2 2 2 0 Syntaxin-like protein ApoA-II PF04711.13 CDO71039.1 - 4.3 7.6 6.1 55 4.0 0.2 4.0 4 0 0 4 4 4 0 Apolipoprotein A-II (ApoA-II) Baculo_PEP_C PF04513.12 CDO71039.1 - 4.6 7.3 11.8 3.6 7.6 4.8 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CBS PF00571.28 CDO71040.1 - 5.2e-15 55.6 2.5 1.2e-05 25.7 0.2 4.6 4 1 0 4 4 4 4 CBS domain CNH PF00780.22 CDO71042.1 - 2.8e-11 43.6 0.0 5.9e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 CNH domain LVIVD PF08309.11 CDO71042.1 - 0.12 11.7 0.2 1 8.8 0.0 2.4 2 0 0 2 2 2 0 LVIVD repeat NiFeSe_Hases PF00374.19 CDO71042.1 - 0.28 10.0 0.0 0.39 9.6 0.0 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Vps39_2 PF10367.9 CDO71043.1 - 1.7e-10 41.3 0.0 6.7e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 CDO71043.1 - 2.1e-07 31.2 2.3 2.9e-06 27.5 0.1 3.2 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 Cys_Met_Meta_PP PF01053.20 CDO71044.1 - 1.3e-20 73.3 0.0 1.8e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CDO71044.1 - 1.7e-05 24.2 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RabGAP-TBC PF00566.18 CDO71045.1 - 4e-21 75.7 0.0 5.5e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribonuc_L-PSP PF01042.21 CDO71047.1 - 9e-18 64.4 0.0 1.1e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribonuc_L-PSP PF01042.21 CDO71048.1 - 1.9e-11 44.0 0.1 2.2e-11 43.8 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HMG_box PF00505.19 CDO71049.1 - 5.2e-10 39.6 0.2 8.9e-10 38.9 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO71049.1 - 0.00093 19.7 0.1 0.0019 18.8 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain AMP-binding PF00501.28 CDO71051.1 - 6.3e-21 74.5 0.0 9e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 CDO71051.1 - 0.017 14.0 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter EAP30 PF04157.16 CDO71052.1 - 1.3e-70 237.4 0.1 2.4e-70 236.5 0.1 1.5 1 0 0 1 1 1 1 EAP30/Vps36 family AP_endonuc_2 PF01261.24 CDO71054.1 - 1.2e-30 106.5 0.0 1.7e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PaREP1 PF05942.11 CDO71054.1 - 0.011 15.6 0.0 0.071 13.0 0.1 2.3 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family TPR_9 PF13371.6 CDO71054.1 - 0.053 13.7 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Meth_synt_2 PF01717.18 CDO71055.1 - 9.5e-08 31.7 0.0 1.8e-06 27.5 0.0 2.5 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CDO71055.1 - 0.0006 19.4 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain DUF755 PF05501.11 CDO71056.1 - 0.86 9.9 8.8 1.9 8.8 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Kelch_4 PF13418.6 CDO71059.1 - 3.5e-32 110.2 7.5 1.2e-06 28.4 0.1 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CDO71059.1 - 3.9e-31 106.7 7.7 1e-07 32.1 0.1 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CDO71059.1 - 1.2e-21 76.2 7.5 5.2e-07 29.7 0.0 5.0 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 CDO71059.1 - 2.5e-21 75.0 9.1 5.4e-06 25.9 0.0 5.6 5 1 0 5 5 5 4 Kelch motif DUF4110 PF13422.6 CDO71059.1 - 5.6e-18 64.8 0.1 5.6e-18 64.8 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.6 CDO71059.1 - 2.6e-17 62.4 13.3 7.3e-05 22.7 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 CDO71059.1 - 8.7e-16 57.2 10.8 3.6e-05 23.6 0.1 5.6 4 1 0 4 4 4 4 Kelch motif BUD22 PF09073.10 CDO71059.1 - 0.82 8.9 26.6 0.27 10.5 14.3 2.3 2 0 0 2 2 2 0 BUD22 Lipase_3 PF01764.25 CDO71060.1 - 6.3e-23 81.2 0.0 8.5e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrophobin PF01185.18 CDO71061.1 - 5.9e-26 90.9 8.1 7e-26 90.7 8.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CPBP PF02517.16 CDO71063.1 - 5.2e-05 23.5 1.5 9.5e-05 22.7 0.4 1.9 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease FUSC-like PF12805.7 CDO71063.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS zf-MYND PF01753.18 CDO71065.1 - 4.7e-11 42.6 17.8 5.4e-10 39.2 17.4 2.4 2 1 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 CDO71065.1 - 0.23 11.8 12.5 0.59 10.5 12.5 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 CDO71065.1 - 0.26 11.4 10.3 8.3 6.6 9.4 2.5 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Viral_Beta_CD PF04530.12 CDO71065.1 - 0.26 11.6 2.0 14 6.0 0.0 2.8 2 1 1 3 3 3 0 Viral Beta C/D like family Sugar_tr PF00083.24 CDO71066.1 - 1.4e-86 291.1 19.5 8.3e-78 262.3 11.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDO71066.1 - 4e-15 55.6 39.5 1.3e-06 27.6 26.1 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily zinc_ribbon_10 PF10058.9 CDO71067.1 - 6.2e-19 67.5 0.3 9.7e-19 66.8 0.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein CCDC-167 PF15188.6 CDO71067.1 - 0.027 14.8 0.7 0.3 11.5 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ANAPC15 PF15243.6 CDO71067.1 - 0.15 12.5 0.5 5.5 7.5 0.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 zf-ACC PF17848.1 CDO71067.1 - 0.31 11.1 1.1 0.72 10.0 1.1 1.7 1 1 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf_C2H2_10 PF18414.1 CDO71067.1 - 0.35 10.4 0.1 0.35 10.4 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-RanBP PF00641.18 CDO71067.1 - 0.41 10.0 1.8 0.47 9.8 0.1 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others NMD3 PF04981.13 CDO71067.1 - 0.45 9.9 2.6 1.4 8.3 0.1 2.1 2 0 0 2 2 2 0 NMD3 family A2L_zn_ribbon PF08792.10 CDO71067.1 - 0.83 9.4 4.9 3.1 7.6 4.9 1.9 1 1 0 1 1 1 0 A2L zinc ribbon domain Band_7 PF01145.25 CDO71068.1 - 0.00011 22.3 11.2 0.034 14.2 8.8 3.2 2 1 0 2 2 2 2 SPFH domain / Band 7 family DivIVA PF05103.13 CDO71068.1 - 0.61 10.2 12.9 1.1 9.4 12.9 1.3 1 0 0 1 1 1 0 DivIVA protein Glyco_transf_20 PF00982.21 CDO71069.1 - 3.1e-154 514.2 0.0 5.7e-154 513.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CDO71069.1 - 1e-70 237.5 0.0 3.3e-70 235.9 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase FAD-SLDH PF12318.8 CDO71069.1 - 0.052 13.6 0.3 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase RRM_1 PF00076.22 CDO71070.1 - 6.9e-50 166.8 0.0 1.7e-15 56.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CDO71070.1 - 0.00047 20.2 0.0 0.43 10.7 0.0 3.5 3 1 0 3 3 3 1 Limkain b1 DUF3343 PF11823.8 CDO71070.1 - 0.00048 19.5 0.0 0.0034 16.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3343) Phage_TAC_13 PF16459.5 CDO71070.1 - 0.026 14.9 0.0 0.46 11.0 0.0 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone, TAC Rax2 PF12768.7 CDO71071.1 - 0.001 18.6 0.2 0.0047 16.4 0.0 1.9 2 0 0 2 2 2 1 Cortical protein marker for cell polarity SKG6 PF08693.10 CDO71071.1 - 0.0042 16.5 7.2 0.0042 16.5 7.2 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain VSP PF03302.13 CDO71071.1 - 0.0096 14.8 3.1 0.015 14.2 3.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF3290 PF11694.8 CDO71071.1 - 0.094 12.7 0.3 1.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) EphA2_TM PF14575.6 CDO71071.1 - 0.098 13.6 0.3 0.21 12.5 0.3 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 CDO71071.1 - 0.19 10.5 0.1 0.26 10.1 0.1 1.1 1 0 0 1 1 1 0 Amnionless MFS_5 PF05631.14 CDO71072.1 - 1.1e-55 189.0 5.9 1.7e-55 188.4 5.9 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CDO71072.1 - 8.9e-18 64.3 27.4 8.9e-18 64.3 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDO71072.1 - 2.4e-05 23.4 0.0 0.00014 20.8 0.0 2.2 1 1 0 1 1 1 1 MFS_1 like family DUF981 PF06168.11 CDO71072.1 - 0.48 10.3 11.5 0.15 12.0 1.0 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF981) DUF4083 PF13314.6 CDO71072.1 - 2.6 8.1 4.5 21 5.2 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Sec23_trunk PF04811.15 CDO71073.1 - 1.1e-56 192.2 0.0 1.6e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CDO71073.1 - 1.8e-26 92.7 0.0 3.8e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CDO71073.1 - 3.2e-26 91.2 0.2 6.3e-26 90.2 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 CDO71073.1 - 1.1e-15 57.3 0.0 3.1e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat MFS_1 PF07690.16 CDO71074.1 - 3.3e-08 32.8 22.9 2.5e-06 26.6 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CDO71075.1 - 4.5e-07 29.1 1.7 4.5e-07 29.1 1.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 CDO71075.1 - 0.0018 16.9 1.1 0.0018 16.9 1.1 1.6 2 0 0 2 2 2 1 MFS/sugar transport protein CitMHS PF03600.16 CDO71075.1 - 0.058 12.6 2.4 0.1 11.8 1.1 1.7 1 1 0 2 2 2 0 Citrate transporter Plavaka PF18759.1 CDO71076.1 - 6.2e-124 413.4 0.0 8.7e-124 413.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase MFS_1 PF07690.16 CDO71078.1 - 0.00061 18.8 13.4 0.034 13.1 8.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4993 PF16384.5 CDO71078.1 - 0.069 12.1 0.6 0.088 11.8 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF3084 PF11283.8 CDO71078.1 - 0.081 12.9 0.2 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) ApoO PF09769.9 CDO71079.1 - 1e-29 103.1 0.9 1.6e-27 96.0 0.0 2.3 2 0 0 2 2 2 2 Apolipoprotein O Apolipoprotein PF01442.18 CDO71079.1 - 1.9e-05 24.7 10.4 0.0015 18.5 8.8 2.3 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 CDO71079.1 - 0.045 13.8 17.0 0.14 12.3 16.0 2.2 1 1 1 2 2 2 0 Late embryogenesis abundant protein DUF883 PF05957.13 CDO71079.1 - 0.25 12.0 8.9 1.4 9.5 3.3 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 CDO71079.1 - 0.44 10.5 13.1 1.2 9.1 0.1 2.7 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Mem_trans PF03547.18 CDO71081.1 - 8.3e-40 136.4 0.0 1.3e-33 116.0 0.0 2.3 2 1 0 2 2 2 2 Membrane transport protein YhhN PF07947.14 CDO71081.1 - 0.57 9.8 7.9 0.21 11.2 4.3 2.1 2 0 0 2 2 2 0 YhhN family PhoLip_ATPase_C PF16212.5 CDO71081.1 - 1 9.0 12.1 0.044 13.5 3.7 2.3 2 1 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal PI3K_P85_iSH2 PF16454.5 CDO71082.1 - 0.013 15.1 3.4 0.034 13.7 3.4 1.6 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc42p PF11544.8 CDO71082.1 - 0.024 14.6 0.1 0.068 13.2 0.1 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p Myb_DNA-bind_5 PF13873.6 CDO71082.1 - 0.035 14.2 0.7 0.093 12.8 0.7 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain ZapB PF06005.12 CDO71082.1 - 0.045 14.2 5.3 0.18 12.2 5.3 2.1 1 0 0 1 1 1 0 Cell division protein ZapB Csm1_N PF18504.1 CDO71082.1 - 0.56 10.6 3.7 1.5 9.2 3.7 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain DDE_Tnp_4 PF13359.6 CDO71083.1 - 8.5e-12 45.0 0.0 1.3e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease KcnmB2_inactiv PF09303.10 CDO71083.1 - 0.092 12.6 0.0 7.3 6.5 0.0 2.5 2 0 0 2 2 2 0 KCNMB2, ball and chain domain Zn_clus PF00172.18 CDO71084.1 - 0.0043 17.2 12.8 0.0064 16.6 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAM33 PF02330.16 CDO71085.1 - 4.9e-65 219.4 0.8 2.8e-64 216.9 0.8 1.8 1 1 0 1 1 1 1 Mitochondrial glycoprotein HTH_23 PF13384.6 CDO71087.1 - 4.5e-06 26.3 0.5 0.00019 21.1 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDO71087.1 - 1.6e-05 25.0 0.5 3.3e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.6 CDO71087.1 - 0.0052 17.4 0.1 0.0082 16.7 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Plavaka PF18759.1 CDO71088.1 - 2.5e-31 109.1 0.0 3e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase PRCC PF10253.9 CDO71088.1 - 3.6 8.3 6.3 5 7.9 6.3 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MFS_1 PF07690.16 CDO71091.1 - 5.6e-09 35.4 18.9 7.5e-09 35.0 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CDO71091.1 - 0.0028 16.6 3.3 0.25 10.2 0.0 2.2 2 0 0 2 2 2 2 MFS_1 like family HRG PF16954.5 CDO71091.1 - 6.4 7.3 10.1 0.095 13.1 1.7 2.4 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene RNase_PH PF01138.21 CDO71092.1 - 1.2e-14 54.9 0.1 1.9e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDO71092.1 - 0.16 12.0 0.0 15 5.7 0.0 2.3 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 LRR_6 PF13516.6 CDO71093.1 - 1.5e-09 37.1 12.7 0.005 16.8 0.1 6.1 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 CDO71093.1 - 0.017 15.5 6.4 0.95 10.0 0.3 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) PsbI PF02532.14 CDO71093.1 - 0.02 14.8 0.3 0.056 13.4 0.3 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) F-box PF00646.33 CDO71093.1 - 0.046 13.6 0.8 0.12 12.3 0.2 2.0 2 0 0 2 2 2 0 F-box domain TFIIE_alpha PF02002.17 CDO71094.1 - 5.2e-18 64.8 0.1 9.1e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 CDO71094.1 - 3.1e-06 27.4 1.9 4.1e-06 27.0 0.4 1.9 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha zf_UBZ PF18439.1 CDO71094.1 - 0.0034 16.9 1.1 1.4 8.6 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger PDZ PF00595.24 CDO71094.1 - 0.011 16.1 0.0 0.039 14.3 0.0 1.9 1 0 0 1 1 1 0 PDZ domain zf-C2H2_6 PF13912.6 CDO71094.1 - 0.015 15.3 1.4 2.1 8.4 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.12 CDO71094.1 - 0.022 14.3 0.3 0.022 14.3 0.3 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding TRAF6_Z2 PF18048.1 CDO71094.1 - 0.033 14.3 1.4 0.08 13.1 1.4 1.6 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 DiS_P_DiS PF06750.13 CDO71094.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zf-C2H2_4 PF13894.6 CDO71094.1 - 0.57 11.2 1.3 8.7 7.5 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.25 CDO71095.1 - 8.5e-18 64.5 0.0 1.1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO71095.1 - 3.4e-09 36.6 0.0 1.1e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF953 PF06110.11 CDO71095.1 - 0.2 11.3 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) adh_short_C2 PF13561.6 CDO71096.1 - 2.2e-12 47.0 0.0 3.8e-12 46.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO71096.1 - 7.4e-07 28.8 0.0 1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NOA36 PF06524.12 CDO71097.1 - 3.7 6.8 7.3 5.5 6.2 7.3 1.2 1 0 0 1 1 1 0 NOA36 protein Aldo_ket_red PF00248.21 CDO71098.1 - 1.3e-44 152.6 0.1 6.6e-43 147.0 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PX PF00787.24 CDO71099.1 - 4.4e-15 55.6 0.0 1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 CDO71099.1 - 1.4e-12 47.6 0.5 1.7e-11 44.1 0.5 2.1 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein PGDH_C PF16896.5 CDO71099.1 - 0.029 14.3 0.1 0.063 13.2 0.1 1.5 1 0 0 1 1 1 0 Phosphogluconate dehydrogenase (decarboxylating) C-term DNA_alkylation PF08713.11 CDO71099.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 DNA alkylation repair enzyme WD40 PF00400.32 CDO71101.1 - 3.1e-76 249.3 59.6 1.1e-07 32.4 0.3 12.8 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO71101.1 - 1.1e-22 80.1 15.6 4.3e-05 23.7 0.1 10.4 4 2 7 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDO71101.1 - 2.7e-09 37.2 1.4 0.054 13.4 0.1 3.5 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDO71101.1 - 3.5e-09 36.1 4.3 0.15 11.0 0.0 7.1 3 2 4 9 9 9 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 CDO71101.1 - 1.5e-07 32.0 0.0 6.6e-07 29.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 CDO71101.1 - 3.7e-06 27.0 0.0 7.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.16 CDO71101.1 - 0.0023 16.5 1.3 0.029 12.9 0.1 3.0 3 0 0 3 3 3 1 Cytochrome D1 heme domain AAA_22 PF13401.6 CDO71101.1 - 0.0029 17.9 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Frtz PF11768.8 CDO71101.1 - 0.0036 15.7 0.3 0.9 7.8 0.1 3.8 3 1 1 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz Coatomer_WDAD PF04053.14 CDO71101.1 - 0.0068 15.5 0.1 0.32 10.0 0.0 2.3 2 0 0 2 2 2 1 Coatomer WD associated region LPP PF04728.13 CDO71101.1 - 0.0074 16.6 0.6 4.5 7.7 0.0 3.6 3 0 0 3 3 3 1 Lipoprotein leucine-zipper ALIX_LYPXL_bnd PF13949.6 CDO71101.1 - 0.0086 15.4 0.3 0.038 13.3 0.2 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Parvo_NS1 PF01057.17 CDO71101.1 - 0.0096 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 WD40_like PF17005.5 CDO71101.1 - 0.031 13.6 0.0 10 5.4 0.0 3.4 2 2 2 4 4 4 0 WD40-like domain PD40 PF07676.12 CDO71101.1 - 0.033 14.2 0.4 36 4.4 0.0 4.8 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 CDO71101.1 - 0.12 11.0 14.1 0.34 9.5 0.1 4.5 4 1 0 5 5 5 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 CDO71101.1 - 0.37 10.1 5.1 1.7 7.9 0.0 3.9 4 1 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Malic_M PF03949.15 CDO71102.1 - 1e-89 300.2 0.0 1.4e-89 299.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDO71102.1 - 7.9e-64 214.8 0.0 1.2e-63 214.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF2070 PF09843.9 CDO71104.1 - 2.9 6.1 4.5 3.7 5.7 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Med15 PF09606.10 CDO71105.1 - 0.016 14.0 2.4 0.77 8.4 0.4 2.7 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Apt1 PF10351.9 CDO71105.1 - 0.065 12.1 0.3 0.099 11.5 0.3 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S41 PF03572.18 CDO71106.1 - 3.6e-05 23.4 0.0 6.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 FixP_N PF14715.6 CDO71107.1 - 0.063 13.0 0.6 28 4.5 0.0 3.2 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP 7tm_7 PF08395.12 CDO71107.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Amino_oxidase PF01593.24 CDO71108.1 - 3e-24 86.1 0.0 7.9e-21 74.9 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDO71108.1 - 2.7e-11 43.5 0.0 6.9e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDO71108.1 - 1.4e-07 31.5 0.1 6.9e-06 25.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CDO71108.1 - 9.4e-06 25.7 0.5 0.00041 20.4 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CDO71108.1 - 0.0002 20.7 0.2 0.05 12.8 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 CDO71108.1 - 0.0012 17.7 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 MCRA family HI0933_like PF03486.14 CDO71108.1 - 0.007 15.1 0.0 0.49 9.0 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 CDO71108.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 CDO71108.1 - 0.02 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDO71108.1 - 0.024 15.2 0.0 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDO71108.1 - 0.041 13.0 0.1 2.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 CDO71108.1 - 0.076 12.2 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 CDO71108.1 - 0.099 11.9 0.0 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DNA_primase_S PF01896.19 CDO71109.1 - 1.9e-45 155.1 0.0 2.8e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 DNA primase small subunit DUF2448 PF10476.9 CDO71109.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) ABC_tran PF00005.27 CDO71111.1 - 3e-41 141.1 0.0 3.1e-27 95.7 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CDO71111.1 - 1.9e-30 106.5 25.7 3.6e-17 62.9 4.1 4.1 4 1 0 4 4 4 2 ABC transporter transmembrane region AAA_29 PF13555.6 CDO71111.1 - 0.00033 20.3 0.9 0.57 10.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CDO71111.1 - 0.0028 17.1 0.1 1.2 8.5 0.0 3.5 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CDO71111.1 - 0.013 15.8 0.1 11 6.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CDO71111.1 - 0.021 14.4 0.1 7.9 6.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CDO71111.1 - 0.034 14.3 0.4 0.15 12.1 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 CDO71111.1 - 0.093 13.1 0.7 1.4 9.3 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 CDO71111.1 - 0.15 12.5 0.4 15 6.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain SieB PF14163.6 CDO71111.1 - 0.3 10.5 1.0 0.75 9.3 1.0 1.6 1 0 0 1 1 1 0 Super-infection exclusion protein B adh_short_C2 PF13561.6 CDO71112.1 - 2.3e-56 191.0 0.0 2.6e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO71112.1 - 3e-52 176.9 0.0 4.4e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO71112.1 - 4.5e-17 62.5 0.1 6.2e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO71112.1 - 8.9e-05 22.1 0.0 0.00017 21.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CDO71112.1 - 0.011 14.9 0.1 0.072 12.2 0.1 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CDO71112.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 CDO71112.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 CDO71112.1 - 0.15 11.9 0.2 0.27 11.0 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_N PF08240.12 CDO71113.1 - 1.2e-29 102.4 1.5 2e-29 101.7 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO71113.1 - 7.5e-22 77.7 0.1 1.2e-21 77.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CDO71113.1 - 2.5e-10 40.2 0.1 1.4e-07 31.2 0.1 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CDO71113.1 - 1.3e-06 29.5 0.0 2.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CDO71113.1 - 0.00051 19.4 0.4 0.0015 17.9 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.12 CDO71113.1 - 0.015 15.9 0.0 0.042 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 CDO71113.1 - 0.019 14.6 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 CDO71113.1 - 0.019 15.6 0.0 0.045 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 CDO71113.1 - 0.039 13.3 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GST_N_2 PF13409.6 CDO71114.1 - 8.3e-43 144.6 0.0 3.7e-20 72.0 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO71114.1 - 5.7e-32 109.6 0.1 2e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDO71114.1 - 2.6e-16 59.6 0.2 4.9e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO71114.1 - 7.4e-11 42.1 0.1 0.00022 21.4 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDO71114.1 - 9.2e-10 38.8 0.0 0.0073 16.7 0.0 4.2 2 2 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CDO71114.1 - 0.00022 20.9 0.3 0.84 9.5 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain DUF4973 PF16343.5 CDO71114.1 - 0.026 14.6 0.0 7.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4973) CBM_35 PF16990.5 CDO71114.1 - 0.064 13.5 0.3 29 4.9 0.0 3.4 4 0 0 4 4 4 0 Carbohydrate binding module (family 35) DNMT1-RFD PF12047.8 CDO71114.1 - 0.066 13.3 0.1 6 6.9 0.0 2.3 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain p450 PF00067.22 CDO71115.1 - 2e-58 198.3 0.0 4.7e-58 197.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SARS_X4 PF08779.10 CDO71115.1 - 0.17 12.1 0.1 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 SARS coronavirus X4 like p450 PF00067.22 CDO71116.1 - 9e-47 159.9 0.0 3.5e-29 101.9 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 Ytca PF17090.5 CDO71116.1 - 0.38 11.3 4.1 0.53 10.8 2.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family p450 PF00067.22 CDO71117.1 - 4.1e-55 187.3 0.0 7.5e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CDO71118.1 - 1.4e-52 179.0 0.0 1.8e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CDO71119.1 - 3.8e-47 161.1 0.0 3.8e-45 154.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Ndufs5 PF10200.9 CDO71120.1 - 5e-05 23.5 0.7 5.6e-05 23.3 0.7 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 CDO71120.1 - 0.00026 20.9 3.6 0.00038 20.4 3.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like PADR1 PF08063.12 CDO71120.1 - 0.0053 16.5 3.4 1 9.2 0.0 2.6 2 1 1 3 3 3 2 PADR1 (NUC008) domain DUF3128 PF11326.8 CDO71120.1 - 0.023 15.1 5.5 0.18 12.2 5.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Rib_hydrolayse PF02267.17 CDO71120.1 - 0.04 13.3 0.0 0.045 13.2 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosyl cyclase Pet191_N PF10203.9 CDO71120.1 - 0.047 14.0 1.3 0.073 13.4 1.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 FAT PF02259.23 CDO71120.1 - 0.076 12.2 0.1 0.09 12.0 0.1 1.0 1 0 0 1 1 1 0 FAT domain CHCH PF06747.13 CDO71120.1 - 0.11 12.7 5.2 2.6 8.3 0.6 2.2 1 1 1 2 2 2 0 CHCH domain NDUF_B7 PF05676.13 CDO71120.1 - 1 9.1 5.7 0.38 10.5 3.2 1.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) ubiquitin PF00240.23 CDO71121.1 - 1.3e-15 56.9 0.0 2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CDO71121.1 - 1.4e-06 28.1 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Blt1 PF12754.7 CDO71121.1 - 0.0012 19.2 0.3 0.0024 18.2 0.3 1.6 1 0 0 1 1 1 1 Blt1 N-terminal domain Imm49 PF15575.6 CDO71121.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 49 OPT PF03169.15 CDO71122.1 - 2e-94 317.4 40.1 2.3e-94 317.2 40.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_61 PF03443.14 CDO71125.1 - 4.1e-63 213.0 0.1 5.4e-63 212.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PWI PF01480.17 CDO71127.1 - 2.8e-28 98.0 0.0 4.1e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 PWI domain SET PF00856.28 CDO71128.1 - 1.3e-16 61.5 0.0 5.2e-16 59.5 0.0 2.0 1 1 0 1 1 1 1 SET domain MR_MLE_C PF13378.6 CDO71129.1 - 1.6e-48 165.2 0.7 9.4e-40 136.5 0.1 2.1 1 1 1 2 2 2 2 Enolase C-terminal domain-like MR_MLE_N PF02746.16 CDO71129.1 - 1.4e-22 80.1 0.0 3.5e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SET PF00856.28 CDO71130.1 - 3.3e-14 53.6 0.0 4.1e-13 50.1 0.0 2.2 1 1 0 1 1 1 1 SET domain GST_N_3 PF13417.6 CDO71131.1 - 9.1e-11 42.0 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO71131.1 - 4.9e-08 33.2 0.0 9.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO71131.1 - 2e-07 31.2 0.1 5.3e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO71131.1 - 0.00022 21.2 0.2 0.00045 20.2 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ATP_bind_1 PF03029.17 CDO71132.1 - 1.7e-73 247.4 0.0 2.1e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CDO71132.1 - 0.14 12.3 0.2 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 CDO71133.1 - 2.4e-14 53.5 0.0 5.4e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CDO71133.1 - 7.2e-10 39.5 1.1 7.2e-10 39.5 1.1 2.4 2 1 0 2 2 2 1 RecQ zinc-binding Helicase_C PF00271.31 CDO71133.1 - 1.1e-07 32.2 0.0 1.4e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO71133.1 - 0.0044 17.1 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DivIC PF04977.15 CDO71133.1 - 1.3 8.9 3.6 3 7.7 3.6 1.5 1 0 0 1 1 1 0 Septum formation initiator CPSF_A PF03178.15 CDO71135.1 - 6.5e-76 255.7 0.0 1.5e-75 254.5 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 CDO71135.1 - 7.9e-14 51.2 0.0 1.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GST_N_3 PF13417.6 CDO71136.1 - 8.6e-07 29.3 0.2 1.7e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO71136.1 - 0.00019 21.7 0.1 0.00048 20.4 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO71136.1 - 0.00063 19.7 0.1 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO71136.1 - 0.0008 19.7 0.0 0.0025 18.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CDO71136.1 - 0.0089 16.2 0.3 0.077 13.2 0.1 2.5 2 1 1 3 3 3 1 Glutaredoxin GST_C_5 PF16865.5 CDO71136.1 - 0.0096 16.5 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDO71136.1 - 0.039 14.2 0.1 0.16 12.2 0.0 2.0 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 CDO71136.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_1 PF00170.21 CDO71137.1 - 5.7e-07 29.5 6.1 3e-06 27.2 6.1 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDO71137.1 - 3.4e-06 27.0 9.8 3.8e-05 23.7 4.3 2.4 1 1 1 2 2 2 2 Basic region leucine zipper RAC_head PF16717.5 CDO71137.1 - 0.16 12.9 0.7 0.35 11.9 0.7 1.5 1 0 0 1 1 1 0 Ribosome-associated complex head domain Catalase-rel PF06628.12 CDO71137.1 - 0.17 12.2 0.4 0.73 10.1 0.1 2.1 2 0 0 2 2 2 0 Catalase-related immune-responsive TMF_DNA_bd PF12329.8 CDO71137.1 - 4.6 7.3 6.5 0.27 11.2 0.8 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PAP2 PF01569.21 CDO71138.1 - 2.4e-16 59.7 4.0 9.6e-16 57.8 4.0 2.0 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CDO71138.1 - 0.066 12.9 18.9 2.6 7.7 18.9 3.3 1 1 0 1 1 1 0 PAP2 superfamily BNIP3 PF06553.12 CDO71138.1 - 0.18 11.5 0.1 0.38 10.4 0.1 1.5 1 0 0 1 1 1 0 BNIP3 DUF4646 PF15496.6 CDO71139.1 - 7.5e-38 130.0 0.0 1.5e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Metallophos PF00149.28 CDO71141.1 - 7.8e-34 118.0 0.0 1.2e-33 117.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 CDO71141.1 - 0.11 12.2 0.5 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) UNC-50 PF05216.13 CDO71142.1 - 1.3e-77 260.3 16.7 1.7e-77 259.9 16.7 1.1 1 0 0 1 1 1 1 UNC-50 family CTP_transf_1 PF01148.20 CDO71142.1 - 0.053 13.3 5.9 0.08 12.7 5.9 1.3 1 0 0 1 1 1 0 Cytidylyltransferase family DUF1772 PF08592.11 CDO71142.1 - 0.43 10.9 9.0 3.3 8.0 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) WW PF00397.26 CDO71143.1 - 5.4e-05 23.2 1.1 0.00013 22.0 1.1 1.7 1 0 0 1 1 1 1 WW domain PGM_PMM_I PF02878.16 CDO71145.1 - 6e-37 126.4 0.2 1.1e-36 125.6 0.2 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CDO71145.1 - 8.7e-26 90.4 0.0 1.6e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CDO71145.1 - 2.5e-14 53.7 0.0 6.8e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CDO71145.1 - 0.00013 22.0 0.0 0.00034 20.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2236 PF09995.9 CDO71146.1 - 6e-28 98.6 6.6 7.1e-28 98.3 0.9 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) SPR1 PF15356.6 CDO71146.1 - 0.65 10.5 6.2 0.11 13.0 1.9 1.9 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 TPR_11 PF13414.6 CDO71147.1 - 1.5e-13 50.2 7.8 4.6e-08 32.6 0.3 4.3 2 2 2 4 4 4 3 TPR repeat TPR_2 PF07719.17 CDO71147.1 - 8.6e-11 41.1 13.7 3.4e-07 29.9 0.0 5.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDO71147.1 - 4.3e-09 36.1 0.1 0.033 14.6 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDO71147.1 - 7.5e-09 36.1 1.4 2.7e-05 24.7 0.1 3.7 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDO71147.1 - 1.4e-08 34.2 12.3 2.6e-07 30.2 0.0 4.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CDO71147.1 - 1.6e-08 34.9 3.1 0.00083 19.8 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDO71147.1 - 2.7e-08 34.0 7.7 0.00025 21.6 0.0 5.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDO71147.1 - 1.1e-07 32.0 9.7 0.00051 20.3 0.2 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDO71147.1 - 1.6e-05 24.6 3.3 0.0055 16.5 0.0 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDO71147.1 - 0.00027 21.4 0.2 0.038 14.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDO71147.1 - 0.00037 20.5 12.3 0.023 14.9 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDO71147.1 - 0.00038 19.8 0.5 0.00066 19.0 0.5 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDO71147.1 - 0.0018 18.1 5.0 0.072 13.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 CDO71147.1 - 0.0034 17.4 0.1 0.0084 16.1 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 ANAPC3 PF12895.7 CDO71147.1 - 0.016 15.4 3.6 0.066 13.5 0.2 2.7 1 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 CDO71147.1 - 0.021 15.2 1.7 0.29 11.5 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 CDO71147.1 - 0.028 14.5 1.7 2.6 8.1 1.1 3.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) DUF1771 PF08590.10 CDO71147.1 - 0.69 10.3 7.0 12 6.4 2.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) Exonuc_VII_S PF02609.16 CDO71147.1 - 0.99 9.5 7.8 4.7 7.4 0.1 3.7 4 0 0 4 4 3 0 Exonuclease VII small subunit MIT PF04212.18 CDO71147.1 - 3.4 7.8 9.6 15 5.7 0.2 3.8 2 2 2 4 4 4 0 MIT (microtubule interacting and transport) domain MCPVI PF02993.14 CDO71148.1 - 0.86 9.4 5.2 2 8.2 5.2 1.5 1 0 0 1 1 1 0 Minor capsid protein VI MGC-24 PF05283.11 CDO71149.1 - 0.015 15.8 0.7 0.015 15.8 0.7 3.0 4 0 0 4 4 4 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CorA PF01544.18 CDO71150.1 - 9.4e-12 44.8 2.5 1.4e-11 44.3 2.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 CDO71150.1 - 0.02 13.8 0.1 0.029 13.3 0.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily YiaAB PF05360.14 CDO71150.1 - 0.19 12.0 2.0 0.44 10.8 2.0 1.6 1 0 0 1 1 1 0 yiaA/B two helix domain AAA PF00004.29 CDO71152.1 - 2.3e-44 151.0 0.0 3.9e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CDO71152.1 - 2.9e-08 34.0 0.0 6.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CDO71152.1 - 1.9e-06 27.9 0.0 7.7e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDO71152.1 - 6.7e-06 26.6 0.0 7.8e-05 23.1 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDO71152.1 - 9.7e-06 25.9 0.2 0.0051 17.1 0.2 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CDO71152.1 - 4.8e-05 23.1 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_ID_OB PF16450.5 CDO71152.1 - 0.00026 20.9 0.8 0.0032 17.4 0.8 2.5 1 1 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain TIP49 PF06068.13 CDO71152.1 - 0.00083 18.7 0.0 0.0022 17.3 0.0 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CDO71152.1 - 0.0012 19.0 0.0 0.0032 17.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 CDO71152.1 - 0.002 17.9 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 CDO71152.1 - 0.0048 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CDO71152.1 - 0.0052 17.3 0.0 0.021 15.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain PhoH PF02562.16 CDO71152.1 - 0.0064 16.0 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 CDO71152.1 - 0.007 15.8 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CDO71152.1 - 0.0098 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CDO71152.1 - 0.012 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CDO71152.1 - 0.012 15.3 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain TMF_TATA_bd PF12325.8 CDO71152.1 - 0.014 15.6 0.9 0.024 14.9 0.1 1.9 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding ATPase PF06745.13 CDO71152.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 CDO71152.1 - 0.019 14.7 0.1 0.096 12.4 0.0 2.2 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.13 CDO71152.1 - 0.024 13.8 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 CDO71152.1 - 0.028 14.4 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDO71152.1 - 0.03 13.8 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CDO71152.1 - 0.04 14.3 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_13 PF13166.6 CDO71152.1 - 0.052 12.2 0.5 2.2 6.8 0.3 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CDO71152.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CDO71152.1 - 0.062 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDO71152.1 - 0.074 13.4 0.1 0.41 11.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain GvpK PF05121.12 CDO71152.1 - 0.094 12.8 1.9 18 5.4 0.9 2.7 2 0 0 2 2 2 0 Gas vesicle protein K Zeta_toxin PF06414.12 CDO71152.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 CDO71152.1 - 0.1 12.4 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDO71152.1 - 0.16 11.9 0.0 0.7 9.8 0.0 1.9 1 1 1 2 2 2 0 NACHT domain APG6_N PF17675.1 CDO71152.1 - 0.27 11.7 3.6 0.54 10.8 3.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 CDO71152.1 - 0.41 10.4 5.0 0.96 9.3 5.0 1.6 1 0 0 1 1 1 0 Septum formation initiator AAA_12 PF13087.6 CDO71155.1 - 1.2e-48 165.4 0.0 1.6e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDO71155.1 - 7.5e-25 88.2 0.0 2.3e-12 47.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CDO71155.1 - 8.9e-13 48.4 0.0 5.6e-12 45.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDO71155.1 - 7.2e-10 39.4 0.0 5.8e-09 36.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 CDO71155.1 - 3.5e-05 23.9 0.0 7.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CDO71155.1 - 0.00027 20.6 0.0 0.0081 15.7 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 CDO71155.1 - 0.00041 19.9 0.0 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein UvrD_C PF13361.6 CDO71155.1 - 0.013 15.0 0.4 0.22 10.9 0.1 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.21 CDO71155.1 - 0.014 14.8 0.0 0.051 13.0 0.0 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.6 CDO71155.1 - 0.039 13.8 0.4 0.2 11.5 0.4 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain T2SSE PF00437.20 CDO71155.1 - 0.044 12.8 0.0 0.11 11.5 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 CDO71155.1 - 0.049 14.0 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CDO71155.1 - 0.055 13.7 0.0 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 CDO71155.1 - 0.074 12.2 0.0 11 5.1 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_5 PF07728.14 CDO71155.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 CDO71155.1 - 0.22 10.6 0.0 2.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_12 PF13087.6 CDO71156.1 - 9.7e-46 155.9 0.0 1.3e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDO71156.1 - 3.7e-11 43.3 0.0 6.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDO71156.1 - 1.6e-06 27.9 0.0 4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 CDO71156.1 - 0.0052 16.2 0.1 0.31 10.4 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CDO71156.1 - 0.0079 16.0 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CDO71156.1 - 0.016 15.6 0.0 0.093 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 CDO71156.1 - 0.061 13.2 0.4 0.31 10.9 0.4 2.2 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Pkinase_fungal PF17667.1 CDO71157.1 - 8.8e-09 34.6 0.3 1.4e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Creatinase_N_2 PF16189.5 CDO71158.1 - 1.1e-53 181.6 0.1 2e-53 180.8 0.1 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CDO71158.1 - 3.3e-36 125.0 0.0 5.1e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CDO71158.1 - 2.6e-24 85.0 0.4 7.9e-24 83.5 0.1 2.0 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CDO71158.1 - 4.7e-07 30.5 0.2 0.033 14.8 0.1 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Mg_trans_NIPA PF05653.14 CDO71159.1 - 3e-96 322.0 10.7 4.7e-96 321.4 10.7 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CDO71159.1 - 0.0034 17.6 3.3 0.0034 17.6 3.3 3.9 3 1 1 4 4 4 2 EamA-like transporter family Ribosomal_S7 PF00177.21 CDO71160.1 - 7.2e-26 90.6 0.1 1.1e-25 90.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Aldedh PF00171.22 CDO71161.1 - 4.4e-83 279.3 0.0 5.3e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF647 PF04884.14 CDO71162.1 - 5.4e-60 203.0 4.4 8.6e-60 202.3 4.4 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis p450 PF00067.22 CDO71162.1 - 1.7e-51 175.4 0.0 2.4e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 BBE PF08031.12 CDO71163.1 - 3.9e-07 30.1 0.0 6.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like HTH_OrfB_IS605 PF12323.8 CDO71163.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain FAD_binding_4 PF01565.23 CDO71164.1 - 9.5e-11 41.6 0.3 2e-10 40.5 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CDO71164.1 - 4.8e-09 36.2 0.2 9.3e-09 35.3 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_16 PF10294.9 CDO71165.1 - 0.0047 16.7 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CDO71165.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Aldo_ket_red PF00248.21 CDO71166.1 - 8.2e-23 81.0 0.0 6.9e-21 74.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Thioredox_DsbH PF03190.15 CDO71167.1 - 1.7e-70 236.2 0.0 2.8e-70 235.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 CDO71167.1 - 4.7e-08 33.1 0.0 1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like APH PF01636.23 CDO71168.1 - 1.7e-12 47.8 0.1 7e-12 45.8 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDO71168.1 - 0.0011 18.7 0.1 0.3 10.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Pkinase_Tyr PF07714.17 CDO71168.1 - 0.0022 17.3 0.1 0.039 13.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Fructosamin_kin PF03881.14 CDO71168.1 - 0.018 14.3 0.0 3.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Choline_kinase PF01633.20 CDO71168.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 CDO71168.1 - 0.19 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase HLH PF00010.26 CDO71171.1 - 1.4e-18 66.6 0.0 9.4e-18 63.9 0.0 2.4 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain NAD_binding_10 PF13460.6 CDO71173.1 - 2.7e-05 24.2 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF3070 PF11270.8 CDO71173.1 - 0.0089 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3070) LBR_tudor PF09465.10 CDO71173.1 - 0.041 13.7 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain NmrA PF05368.13 CDO71173.1 - 0.17 11.4 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Sin3a_C PF16879.5 CDO71174.1 - 1.7e-73 247.9 1.7 3.3e-73 246.9 0.0 2.4 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 CDO71174.1 - 1.7e-39 133.8 0.7 9.5e-39 131.4 0.2 2.5 3 0 0 3 3 3 1 Sin3 family co-repressor PAH PF02671.21 CDO71174.1 - 2.9e-32 110.5 1.1 2.3e-18 66.0 0.0 4.0 4 0 0 4 4 4 3 Paired amphipathic helix repeat IF4E PF01652.18 CDO71175.1 - 5e-54 182.4 0.0 6.9e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1102 PF06510.11 CDO71175.1 - 0.039 14.1 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) Glyco_hydro_18 PF00704.28 CDO71176.1 - 5.9e-64 216.7 1.7 7.8e-64 216.4 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF390 PF04094.14 CDO71176.1 - 0.16 10.2 2.3 0.25 9.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) AF-4 PF05110.13 CDO71176.1 - 6 4.8 6.2 7.6 4.5 6.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Med22 PF06179.12 CDO71177.1 - 1.1e-15 57.7 5.3 1.5e-15 57.3 5.3 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex UCH PF00443.29 CDO71178.1 - 2.7e-42 145.0 0.0 3.7e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDO71178.1 - 3.8e-10 39.9 0.4 0.00032 20.4 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Macoilin PF09726.9 CDO71179.1 - 2.4 6.6 5.5 2.7 6.5 5.5 1.1 1 0 0 1 1 1 0 Macoilin family CDC27 PF09507.10 CDO71179.1 - 7.3 5.9 10.8 9.3 5.5 10.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 F1F0-ATPsyn_F PF10791.9 CDO71180.1 - 4e-30 104.1 0.0 4.6e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 CDO71180.1 - 0.064 13.6 0.0 0.085 13.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f SHMT PF00464.19 CDO71181.1 - 2e-170 566.7 0.0 2.3e-170 566.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CDO71181.1 - 0.00065 19.1 0.0 0.0033 16.8 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CDO71181.1 - 0.024 13.8 0.0 0.056 12.6 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CDO71181.1 - 0.045 13.0 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family COesterase PF00135.28 CDO71182.1 - 1.2e-51 176.2 0.1 5.3e-26 91.6 0.0 3.1 3 0 0 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 CDO71182.1 - 0.00084 19.3 0.0 0.085 12.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1749 PF08538.10 CDO71182.1 - 0.0012 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) SRP19 PF01922.17 CDO71183.1 - 1e-28 100.1 0.0 1.5e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Aldo_ket_red PF00248.21 CDO71184.1 - 3.1e-73 246.5 0.0 3.5e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4449 PF14613.6 CDO71185.1 - 5.5e-38 130.6 4.7 1.9e-37 128.9 0.3 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4449) Aminotran_1_2 PF00155.21 CDO71186.1 - 4.5e-58 197.2 0.0 5.1e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CDO71186.1 - 0.11 11.0 0.0 0.25 9.8 0.0 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 CDO71186.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase zf-MYND PF01753.18 CDO71187.1 - 6.3e-10 39.0 13.4 1.7e-09 37.6 13.4 1.8 1 0 0 1 1 1 1 MYND finger TPR_17 PF13431.6 CDO71187.1 - 0.16 12.4 0.2 1.5 9.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 CDO71189.1 - 1.1e-44 149.5 24.2 1.3e-12 48.0 0.5 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO71189.1 - 8.6e-14 51.6 1.3 0.0011 19.2 0.0 5.2 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO71189.1 - 8.3e-05 21.7 2.0 0.32 9.9 0.0 4.3 3 3 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CDO71189.1 - 0.0046 16.9 2.2 2.6 8.1 0.2 2.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat PAH PF02671.21 CDO71190.1 - 9e-05 22.5 0.4 0.00014 21.9 0.4 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat MqsA_antitoxin PF15731.5 CDO71190.1 - 0.072 13.2 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HEAT PF02985.22 CDO71190.1 - 0.099 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 HEAT repeat DUF4336 PF14234.6 CDO71191.1 - 4.6e-11 42.5 0.1 0.0035 16.6 0.0 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) MAF_flag10 PF01973.18 CDO71191.1 - 0.05 13.3 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 PIF1 PF05970.14 CDO71194.1 - 4.4e-59 200.5 0.0 1.9e-32 112.9 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.6 CDO71194.1 - 3.1e-36 125.4 0.1 6.5e-36 124.3 0.1 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus zf-C2H2 PF00096.26 CDO71194.1 - 1.4e-08 34.7 14.5 0.048 14.1 0.3 6.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO71194.1 - 3.4e-07 30.5 24.5 0.23 12.4 0.1 7.9 7 0 0 7 7 7 3 C2H2-type zinc finger AAA_30 PF13604.6 CDO71194.1 - 7.3e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain zf-met PF12874.7 CDO71194.1 - 1.8e-05 25.0 11.4 4.7 7.7 0.1 6.2 6 0 0 6 6 6 2 Zinc-finger of C2H2 type zf-RING_5 PF14634.6 CDO71194.1 - 7.8e-05 22.6 11.7 7.8e-05 22.6 11.7 4.1 5 1 0 5 5 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDO71194.1 - 0.00082 19.2 12.8 0.00082 19.2 12.8 3.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO71194.1 - 0.0014 19.0 11.9 0.0014 19.0 11.9 4.0 3 1 1 5 5 3 1 Ring finger domain AAA_16 PF13191.6 CDO71194.1 - 0.0028 18.1 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF2791 PF10923.8 CDO71194.1 - 0.003 16.4 0.1 0.0049 15.8 0.1 1.2 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) zf-RING_UBOX PF13445.6 CDO71194.1 - 0.004 17.1 9.6 0.015 15.3 8.4 2.7 2 0 0 2 2 2 1 RING-type zinc-finger AAA_19 PF13245.6 CDO71194.1 - 0.023 15.0 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-C2H2_jaz PF12171.8 CDO71194.1 - 0.035 14.4 19.6 1.4 9.3 0.0 6.0 6 0 0 6 6 5 0 Zinc-finger double-stranded RNA-binding TrwB_AAD_bind PF10412.9 CDO71194.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 CDO71194.1 - 0.083 12.8 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain zf-C2H2_11 PF16622.5 CDO71194.1 - 0.69 9.7 4.9 2.9 7.8 0.0 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF2175 PF09943.9 CDO71194.1 - 0.7 10.2 2.8 4.4 7.7 0.3 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf_UBZ PF18439.1 CDO71194.1 - 1 9.0 11.3 15 5.3 0.2 5.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 CDO71194.1 - 2.6 8.1 12.2 19 5.4 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C3HC4_4 PF15227.6 CDO71194.1 - 4.9 7.4 14.3 3 8.1 10.9 2.6 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Cu-oxidase PF00394.22 CDO71195.1 - 3.4e-41 141.0 0.1 8e-36 123.5 0.1 3.4 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 CDO71195.1 - 4.1e-27 94.6 2.2 2.2e-24 85.7 0.3 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CDO71195.1 - 1.4e-17 63.8 0.4 1.4e-17 63.8 0.4 3.8 4 1 0 5 5 5 1 Multicopper oxidase EGF_2 PF07974.13 CDO71196.1 - 3.8 8.0 10.4 3.2 8.2 5.3 2.6 3 0 0 3 3 3 0 EGF-like domain Hira PF07569.11 CDO71197.1 - 1.3e-58 198.4 0.1 4e-58 196.7 0.0 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 CDO71197.1 - 3e-27 94.3 10.7 5.9e-07 30.1 0.1 6.3 6 0 0 6 6 5 4 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 CDO71197.1 - 1.2e-08 34.6 5.5 1.2e-08 34.6 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO71197.1 - 2e-08 34.1 7.9 4.7e-08 32.9 7.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger ANAPC4_WD40 PF12894.7 CDO71197.1 - 4.6e-08 33.3 0.7 0.17 12.2 0.0 5.6 2 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4 PF00097.25 CDO71197.1 - 7.4e-07 28.9 5.8 7.4e-07 28.9 5.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO71197.1 - 8.9e-06 25.9 6.0 8.9e-06 25.9 6.0 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 CDO71197.1 - 2.2e-05 24.3 6.1 2.2e-05 24.3 6.1 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDO71197.1 - 2.8e-05 24.2 7.1 0.0001 22.4 7.1 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CDO71197.1 - 0.00016 21.5 4.9 0.00016 21.5 4.9 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDO71197.1 - 0.0093 15.8 4.3 0.024 14.5 4.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CDO71197.1 - 0.012 15.9 3.0 0.036 14.4 3.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C2H2_jaz PF12171.8 CDO71197.1 - 0.015 15.6 7.4 0.022 15.1 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Mcl1_mid PF12341.8 CDO71197.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region zf-RING_6 PF14835.6 CDO71197.1 - 0.045 13.6 1.1 0.11 12.4 1.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.26 CDO71197.1 - 0.046 14.2 1.8 3.7 8.2 0.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 CDO71197.1 - 0.066 13.6 0.2 0.066 13.6 0.2 3.2 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-RING_10 PF16685.5 CDO71197.1 - 0.19 11.9 6.2 0.1 12.8 3.5 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 NOA36 PF06524.12 CDO71197.1 - 0.22 10.8 6.5 0.38 10.0 6.5 1.3 1 0 0 1 1 1 0 NOA36 protein zf-Nse PF11789.8 CDO71197.1 - 0.43 10.4 1.9 0.88 9.4 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-PARP PF00645.18 CDO71198.1 - 4.3e-43 146.1 12.3 1.5e-21 77.1 1.1 2.9 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF2175 PF09943.9 CDO71198.1 - 0.12 12.6 0.3 3 8.2 0.2 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF3280 PF11684.8 CDO71198.1 - 1.8 9.0 5.4 8 6.9 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2380) Ribosomal_S26e PF01283.19 CDO71199.1 - 4e-54 181.6 11.0 4.9e-54 181.3 11.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 CDO71199.1 - 0.021 15.4 0.7 0.82 10.3 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf_CopZ PF18423.1 CDO71199.1 - 0.03 14.3 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 Zinc binding domain YL1 PF05764.13 CDO71201.1 - 0.00065 19.9 1.0 0.00065 19.9 1.0 2.1 3 0 0 3 3 3 1 YL1 nuclear protein HLH PF00010.26 CDO71201.1 - 0.006 16.5 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4611 PF15387.6 CDO71201.1 - 0.0086 16.3 3.3 0.0086 16.3 3.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) F-box-like PF12937.7 CDO71201.1 - 0.084 12.8 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 F-box-like Sigma70_ner PF04546.13 CDO71201.1 - 6.1 6.7 8.5 1.1 9.1 4.3 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Ysc84 PF04366.12 CDO71202.1 - 2.8e-36 124.1 0.2 5e-36 123.3 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CDO71202.1 - 8.1e-16 57.4 0.1 1.8e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDO71202.1 - 1.1e-15 57.0 0.2 6.8e-15 54.5 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 CDO71202.1 - 3.7e-12 45.9 0.0 9.1e-12 44.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain PHF5 PF03660.14 CDO71203.1 - 2.4e-52 175.5 7.9 2.7e-52 175.3 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 CDO71203.1 - 0.039 11.8 4.8 0.043 11.7 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 CDO71203.1 - 0.36 10.9 15.0 1.3 9.2 1.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 CDO71203.1 - 1.4 9.2 17.1 0.29 11.5 2.2 2.6 1 1 1 2 2 2 0 C1 domain DDE_Tnp_4 PF13359.6 CDO71204.1 - 8.7e-18 64.5 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO71204.1 - 2.6e-05 23.9 0.0 6.4e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO71204.1 - 0.0042 16.7 0.1 0.0072 16.0 0.1 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO71204.1 - 0.031 14.6 0.1 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain DDE_Tnp_4 PF13359.6 CDO71206.1 - 8.7e-18 64.5 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO71206.1 - 2.6e-05 23.9 0.0 6.4e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO71206.1 - 0.0042 16.7 0.1 0.0072 16.0 0.1 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO71206.1 - 0.031 14.6 0.1 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 CDO71207.1 - 0.00013 22.8 0.1 0.00035 21.5 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO71207.1 - 0.001 19.4 0.4 0.0027 18.0 0.2 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain AA_permease_2 PF13520.6 CDO71208.1 - 1.4e-29 103.2 28.0 1.4e-16 60.3 16.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 CDO71208.1 - 4.6e-09 35.4 25.0 2.6e-05 23.0 3.3 2.2 1 1 1 2 2 2 2 Amino acid permease DUF2040 PF09745.9 CDO71209.1 - 6.2e-39 132.8 26.8 6.2e-39 132.8 26.8 3.6 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) RRM_1 PF00076.22 CDO71210.1 - 1.2e-10 41.0 0.1 5.4e-09 35.8 0.1 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PG_isomerase_N PF18353.1 CDO71210.1 - 0.11 12.8 0.1 0.3 11.5 0.0 1.7 1 1 1 2 2 2 0 Phosphoglucose isomerase N-terminal domain TFIID-18kDa PF02269.16 CDO71211.1 - 1.5e-20 73.0 0.1 2.1e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 CDO71211.1 - 0.0034 17.7 0.0 0.0054 17.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Nucleo_P87 PF07267.11 CDO71211.1 - 2.7 6.7 6.7 3.7 6.3 6.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF908 PF06012.12 CDO71211.1 - 5 6.4 6.6 7.2 5.9 6.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) ECR1_N PF14382.6 CDO71212.1 - 1e-14 54.0 0.2 1.9e-14 53.1 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CDO71212.1 - 1.4e-14 54.2 0.1 2.9e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 KH domain DUF4211 PF13926.6 CDO71213.1 - 5.8e-33 114.0 1.3 1.7e-32 112.5 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) DUF86 PF01934.17 CDO71213.1 - 0.14 12.1 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF86 DNA_pol_phi PF04931.13 CDO71213.1 - 2.5 6.1 8.0 4.3 5.3 8.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi CHZ PF09649.10 CDO71213.1 - 9.4 5.8 9.7 0.32 10.5 0.2 2.8 2 0 0 2 2 2 0 Histone chaperone domain CHZ DNA_methylase PF00145.17 CDO71215.1 - 2.4e-40 138.9 0.0 3.8e-38 131.7 0.0 3.0 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 CDO71215.1 - 7.5e-14 51.6 0.0 5e-06 26.4 0.2 2.7 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 CDO71215.1 - 1e-08 35.4 0.0 1.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain DDE_3 PF13358.6 CDO71216.1 - 0.064 13.0 0.3 11 5.8 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease Dimer_Tnp_hAT PF05699.14 CDO71217.1 - 6.2e-15 54.8 0.0 1.6e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-TAZ PF02135.16 CDO71217.1 - 0.11 13.0 0.8 0.28 11.7 0.8 1.7 1 0 0 1 1 1 0 TAZ zinc finger OST3_OST6 PF04756.13 CDO71218.1 - 3e-91 305.8 0.0 3.4e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 CDO71218.1 - 0.0033 17.4 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DMT_YdcZ PF04657.13 CDO71218.1 - 0.028 14.7 0.2 0.028 14.7 0.2 2.4 2 1 0 2 2 2 0 Putative inner membrane exporter, YdcZ Sec16_C PF12931.7 CDO71219.1 - 1.1e-99 333.9 0.0 1.5e-99 333.5 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CDO71219.1 - 3.1e-27 95.5 0.1 2e-26 92.9 0.0 2.6 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region PUF PF00806.19 CDO71220.1 - 8.7e-66 214.1 1.4 5.7e-08 32.0 0.1 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat DUF2141 PF09912.9 CDO71220.1 - 0.08 12.9 0.0 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) Elf1 PF05129.13 CDO71221.1 - 2.3e-28 98.0 0.6 2.9e-28 97.7 0.6 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DpnI PF06044.12 CDO71221.1 - 0.0078 15.9 0.1 0.0081 15.8 0.1 1.1 1 0 0 1 1 1 1 Dam-replacing family zf-CHY PF05495.12 CDO71221.1 - 0.038 14.5 1.0 0.055 14.0 1.0 1.3 1 0 0 1 1 1 0 CHY zinc finger Kinesin PF00225.23 CDO71222.1 - 4.2e-110 367.8 0.0 3.1e-109 364.9 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CDO71222.1 - 2.5e-25 89.2 0.0 1.1e-24 87.1 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 CDO71222.1 - 4.4e-05 23.9 0.3 4.4e-05 23.9 0.3 3.5 5 0 0 5 5 5 1 Kinesin-associated microtubule-binding Vps55 PF04133.14 CDO71223.1 - 1.4e-43 147.6 3.4 1.6e-43 147.4 3.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2933 PF11666.8 CDO71223.1 - 9.7 6.3 7.4 20 5.3 7.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) TRAPPC9-Trs120 PF08626.11 CDO71224.1 - 8.8e-184 613.0 0.0 1.2e-140 470.1 0.0 3.8 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit GMC_oxred_N PF00732.19 CDO71225.1 - 3e-57 194.3 0.0 4.5e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase PI3_PI4_kinase PF00454.27 CDO71225.1 - 9.2e-37 127.2 0.0 6.6e-36 124.4 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GMC_oxred_C PF05199.13 CDO71225.1 - 5.7e-34 117.7 0.0 1.4e-33 116.5 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 CDO71225.1 - 1.9e-05 24.0 0.0 4.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 CDO71225.1 - 6.6e-05 23.1 0.1 0.00022 21.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDO71225.1 - 0.0012 18.5 0.9 0.0027 17.3 0.5 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CDO71225.1 - 0.0016 17.5 0.1 0.0027 16.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CDO71225.1 - 0.011 14.9 0.2 0.017 14.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 CDO71225.1 - 0.027 13.7 0.1 0.077 12.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO71225.1 - 0.1 12.6 0.2 0.26 11.3 0.2 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Glyco_transf_15 PF01793.16 CDO71226.1 - 1.7e-122 408.7 8.2 2.1e-109 365.7 6.5 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase TFIIA PF03153.13 CDO71227.1 - 0.012 15.7 14.5 0.013 15.5 14.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit USP7_ICP0_bdg PF12436.8 CDO71229.1 - 3.9e-88 294.8 1.4 3.1e-87 291.9 0.6 2.6 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 CDO71229.1 - 1e-68 231.1 7.0 9.8e-66 221.4 1.1 3.6 3 1 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 CDO71229.1 - 1e-49 169.3 0.1 2e-49 168.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDO71229.1 - 1.1e-21 77.8 0.0 3.3e-21 76.2 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 CDO71229.1 - 2e-07 31.1 0.1 3.5e-06 27.1 0.0 2.9 3 0 0 3 3 3 1 MATH domain ubiquitin PF00240.23 CDO71229.1 - 0.017 14.9 0.5 7.4 6.4 0.0 4.5 5 0 0 5 5 5 0 Ubiquitin family HSDR_N_2 PF13588.6 CDO71229.1 - 0.036 14.1 0.2 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Sec66 PF09802.9 CDO71230.1 - 2.9e-59 199.7 0.0 3.6e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3216 PF11505.8 CDO71230.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) SieB PF14163.6 CDO71230.1 - 0.16 11.5 0.1 0.6 9.6 0.0 1.8 2 0 0 2 2 2 0 Super-infection exclusion protein B Citrate_synt PF00285.21 CDO71231.1 - 2.8e-100 335.9 0.0 3.6e-100 335.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain B56 PF01603.20 CDO71233.1 - 1.6e-192 640.0 9.4 1.9e-192 639.8 9.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DNA_primase_lrg PF04104.14 CDO71234.1 - 2.8e-86 289.2 0.0 4.3e-86 288.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CDP-OH_P_transf PF01066.21 CDO71234.1 - 2.8e-12 47.2 0.1 1.2e-11 45.1 0.3 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SMC_Nse1 PF07574.13 CDO71235.1 - 8.4e-33 113.9 2.3 9.4e-32 110.5 2.3 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CDO71235.1 - 8.8e-11 41.9 11.7 1.5e-10 41.2 11.7 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 CDO71235.1 - 1.7e-06 28.3 10.5 3.2e-06 27.4 10.5 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 CDO71235.1 - 0.0013 18.1 3.5 0.0028 17.1 3.5 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 CDO71235.1 - 0.0074 16.1 10.5 0.015 15.1 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CDO71235.1 - 0.012 15.7 4.4 0.022 14.9 4.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-HC5HC2H PF13771.6 CDO71235.1 - 0.014 15.6 8.6 0.046 14.0 8.7 1.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-C3HC4_3 PF13920.6 CDO71235.1 - 0.041 13.7 9.0 0.067 13.1 9.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDO71235.1 - 0.041 13.6 5.2 0.11 12.3 5.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 CDO71235.1 - 0.099 12.9 6.5 0.25 11.6 6.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-HC5HC2H_2 PF13832.6 CDO71235.1 - 0.18 11.9 7.0 0.15 12.3 5.3 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.6 CDO71235.1 - 0.32 11.0 13.0 0.57 10.2 13.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain FYDLN_acid PF09538.10 CDO71235.1 - 0.4 11.4 11.8 1.2 9.8 11.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_4 PF14570.6 CDO71235.1 - 2.1 8.2 12.8 0.57 10.0 9.7 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CDO71235.1 - 3.4 7.9 8.7 11 6.3 8.7 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 CDO71235.1 - 5.5 7.0 10.5 26 4.8 10.7 2.0 1 1 1 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 CDO71235.1 - 5.8 6.9 10.3 47 4.0 9.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 AAA PF00004.29 CDO71236.1 - 1e-36 126.3 0.0 3e-36 124.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDO71236.1 - 2.2e-11 43.4 0.0 5.1e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDO71236.1 - 1.2e-05 25.7 0.0 0.0048 17.3 0.0 3.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDO71236.1 - 0.00026 21.3 0.2 0.034 14.4 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDO71236.1 - 0.00037 20.7 0.0 0.0034 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CDO71236.1 - 0.0011 19.6 0.1 0.04 14.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 CDO71236.1 - 0.0016 18.5 0.1 0.0078 16.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 CDO71236.1 - 0.0028 16.7 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 CDO71236.1 - 0.0052 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CDO71236.1 - 0.014 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CDO71236.1 - 0.016 15.4 0.0 0.2 11.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CDO71236.1 - 0.045 13.5 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CDO71236.1 - 0.063 13.1 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CDO71236.1 - 0.071 12.7 1.7 4.3 6.9 0.0 3.8 4 0 0 4 4 4 0 AAA domain DUF815 PF05673.13 CDO71236.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.15 CDO71236.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 CDO71236.1 - 0.092 12.5 0.0 0.44 10.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CDO71236.1 - 0.1 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 CDO71236.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain TniB PF05621.11 CDO71236.1 - 0.18 11.2 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_17 PF13207.6 CDO71236.1 - 0.2 12.1 2.7 1.6 9.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain CDP-OH_P_transf PF01066.21 CDO71237.1 - 7.4e-14 52.3 0.4 7.4e-14 52.3 0.4 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FAD_binding_3 PF01494.19 CDO71238.1 - 6.1e-16 58.6 0.0 9.8e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 CDO71238.1 - 0.036 13.1 0.1 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase AT_hook PF02178.19 CDO71239.1 - 6.1e-05 22.4 55.9 0.022 14.6 5.8 4.6 4 0 0 4 4 4 4 AT hook motif PRKCSH PF07915.13 CDO71240.1 - 1.4e-11 45.2 0.0 2.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 CDO71240.1 - 0.034 13.8 0.0 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Pkinase PF00069.25 CDO71241.1 - 1.1e-46 159.3 0.0 1.6e-45 155.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71241.1 - 9.8e-28 97.1 0.0 1.6e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO71241.1 - 0.0076 16.2 0.1 0.022 14.7 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO71241.1 - 0.086 11.8 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DEAD PF00270.29 CDO71243.1 - 7.1e-48 162.7 0.0 1.5e-46 158.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO71243.1 - 2.6e-29 101.8 0.0 2.2e-28 98.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO71243.1 - 0.00035 20.6 0.1 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DivIC PF04977.15 CDO71243.1 - 3.5 7.5 15.3 11 5.8 15.3 1.9 1 0 0 1 1 1 0 Septum formation initiator DNA_ligase_IV PF11411.8 CDO71245.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA ligase IV Pkinase PF00069.25 CDO71246.1 - 9.2e-49 166.2 0.1 1.2e-48 165.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71246.1 - 6.4e-27 94.5 0.0 8.7e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO71246.1 - 9.2e-05 21.4 0.4 0.00014 20.8 0.4 1.3 1 1 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CDO71246.1 - 0.00038 20.0 0.0 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 CDO71246.1 - 0.00059 19.3 0.1 0.00085 18.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO71246.1 - 0.03 14.2 0.0 0.039 13.9 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Histone PF00125.24 CDO71248.1 - 3.6e-27 95.3 0.0 5.4e-27 94.7 0.0 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TRAM_LAG1_CLN8 PF03798.16 CDO71250.1 - 9.4e-34 116.9 25.2 9.4e-34 116.9 25.2 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CDO71250.1 - 7.1e-20 70.4 0.0 1.7e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein DUF639 PF04842.12 CDO71250.1 - 0.11 11.8 2.5 0.19 11.1 2.5 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) TRAM_LAG1_CLN8 PF03798.16 CDO71251.1 - 1.9e-33 115.9 24.2 1.9e-33 115.9 24.2 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CDO71251.1 - 3.8e-21 74.5 0.4 3.8e-21 74.5 0.4 2.2 2 0 0 2 2 2 1 TRAM1-like protein EloA-BP1 PF15870.5 CDO71252.1 - 1.4e-05 25.4 0.4 0.00099 19.4 0.4 2.3 1 1 0 1 1 1 1 ElonginA binding-protein 1 CHORD PF04968.12 CDO71252.1 - 0.0075 17.0 6.6 0.14 12.9 7.1 2.6 2 1 0 2 2 2 1 CHORD Clat_adaptor_s PF01217.20 CDO71253.1 - 3.8e-57 192.2 4.7 4.4e-57 192.0 4.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.11 CDO71253.1 - 0.14 11.6 0.7 1.1 8.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1204) Iso_dh PF00180.20 CDO71255.1 - 7.4e-79 265.4 0.0 9.4e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Amidohydro_2 PF04909.14 CDO71257.1 - 6.3e-39 134.5 8.2 5.3e-24 85.5 0.5 3.0 2 1 0 2 2 2 2 Amidohydrolase adh_short PF00106.25 CDO71258.1 - 2.9e-36 124.8 0.0 3.8e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO71258.1 - 9.9e-30 103.8 0.0 1.3e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO71258.1 - 1.1e-12 48.2 0.0 2.2e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDO71258.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 CDO71258.1 - 0.18 11.2 0.0 1.4 8.3 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Transket_pyr PF02779.24 CDO71259.1 - 3.2e-47 160.5 0.1 6.3e-47 159.5 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDO71259.1 - 4.2e-41 139.7 0.3 1e-40 138.5 0.3 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CDO71259.1 - 0.0014 18.9 0.1 0.0034 17.7 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Histidinol_dh PF00815.20 CDO71260.1 - 4.4e-117 391.5 8.6 6.3e-54 183.5 3.0 3.2 1 1 2 3 3 3 3 Histidinol dehydrogenase PRA-CH PF01502.18 CDO71260.1 - 9.5e-25 86.2 0.1 2.2e-24 85.1 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 CDO71260.1 - 2.7e-11 43.8 0.7 4.2e-11 43.1 0.1 1.7 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 CDO71260.1 - 0.0062 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Piwi PF02171.17 CDO71261.1 - 5.4e-73 245.9 0.0 8.2e-57 192.7 0.0 2.2 1 1 1 2 2 2 2 Piwi domain ArgoN PF16486.5 CDO71261.1 - 1e-18 68.2 0.0 1.9e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CDO71261.1 - 1.5e-15 56.6 0.1 6.6e-15 54.5 0.1 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoMid PF16487.5 CDO71261.1 - 1.3e-14 54.2 0.0 3.3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 CDO71261.1 - 1.1e-09 38.4 0.1 2.6e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 CDO71261.1 - 3.7e-09 36.5 0.0 6.5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 PAZ domain Piwi PF02171.17 CDO71262.1 - 2.1e-78 263.6 0.0 6.1e-78 262.1 0.0 1.7 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CDO71262.1 - 1.9e-30 106.2 0.0 3.3e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CDO71262.1 - 6.7e-17 60.9 0.1 3.4e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoMid PF16487.5 CDO71262.1 - 8.2e-16 58.0 0.0 2.4e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 CDO71262.1 - 3.7e-10 40.0 0.1 8.9e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 CDO71262.1 - 3.4e-09 36.6 0.0 6.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 PAZ domain Mito_carr PF00153.27 CDO71264.1 - 2.8e-64 213.1 3.3 4.5e-23 81.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 CDO71264.1 - 0.00042 19.7 0.1 0.017 14.6 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CDO71264.1 - 0.00079 19.2 0.1 0.01 15.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CDO71264.1 - 0.012 16.1 0.1 0.06 13.8 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 CDO71264.1 - 0.017 14.6 1.2 0.047 13.2 0.3 2.2 2 0 0 2 2 2 0 EF hand JIP_LZII PF16471.5 CDO71265.1 - 0.012 15.7 0.9 0.012 15.7 0.9 4.2 3 1 2 5 5 5 0 JNK-interacting protein leucine zipper II Borrelia_orfA PF02414.15 CDO71265.1 - 0.054 13.2 2.4 0.064 12.9 1.2 1.7 1 1 1 2 2 2 0 Borrelia ORF-A Holin_BhlA PF10960.8 CDO71265.1 - 0.54 10.3 5.6 3.3 7.7 0.6 2.8 1 1 1 2 2 2 0 BhlA holin family ING PF12998.7 CDO71265.1 - 1.8 9.2 13.5 1.4 9.6 0.8 3.4 2 2 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding HMMR_N PF15905.5 CDO71265.1 - 1.8 7.9 26.7 0.1 12.0 16.1 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Occludin_ELL PF07303.13 CDO71265.1 - 2 9.2 13.9 1.9 9.3 2.4 3.7 3 1 1 4 4 4 0 Occludin homology domain DUF4407 PF14362.6 CDO71265.1 - 3.4 7.0 25.3 0.25 10.7 19.1 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CDO71266.1 - 2.1e-06 26.9 17.1 0.0018 17.3 1.6 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein Filament PF00038.21 CDO71266.1 - 0.00033 20.3 2.1 0.00033 20.3 2.1 3.1 1 1 0 2 2 2 1 Intermediate filament protein ADIP PF11559.8 CDO71266.1 - 0.0065 16.6 16.2 0.014 15.5 4.6 2.6 2 1 0 2 2 2 2 Afadin- and alpha -actinin-Binding DUF2959 PF11172.8 CDO71266.1 - 0.014 15.6 7.8 0.17 12.0 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) PKcGMP_CC PF16808.5 CDO71266.1 - 0.019 14.8 12.9 2.5 8.0 0.2 4.8 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF724 PF05266.14 CDO71266.1 - 0.028 14.3 15.7 0.052 13.4 2.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Streptin-Immun PF11083.8 CDO71266.1 - 0.036 14.5 2.4 0.91 10.0 0.1 2.9 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein DUF573 PF04504.14 CDO71266.1 - 0.11 13.2 2.1 0.6 10.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF573 ATG16 PF08614.11 CDO71266.1 - 0.11 12.7 21.8 0.36 11.0 6.4 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 CDO71266.1 - 0.21 12.5 14.3 0.24 12.3 2.9 3.1 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4200 PF13863.6 CDO71266.1 - 0.24 11.8 11.6 1.7 9.0 0.4 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Fungal_TACC PF12709.7 CDO71266.1 - 0.36 11.3 0.2 0.36 11.3 0.2 2.8 4 1 0 4 4 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins MscS_porin PF12795.7 CDO71266.1 - 0.42 10.1 22.2 1 8.9 1.5 4.0 2 2 2 4 4 4 0 Mechanosensitive ion channel porin domain Plasmid_RAQPRD PF09686.10 CDO71266.1 - 0.95 9.7 14.0 1 9.6 0.1 4.2 3 1 1 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) RasGAP_C PF03836.15 CDO71266.1 - 1.3 9.1 6.2 2.4 8.3 1.0 2.5 2 1 0 2 2 2 0 RasGAP C-terminus Rho_Binding PF08912.11 CDO71266.1 - 1.5 9.6 9.9 1.5 9.7 1.2 3.3 3 1 1 4 4 3 0 Rho Binding UPF0242 PF06785.11 CDO71266.1 - 2.3 8.3 14.9 0.55 10.3 1.3 2.8 3 1 0 3 3 2 0 Uncharacterised protein family (UPF0242) N-terminus UPF0184 PF03670.13 CDO71266.1 - 2.6 8.5 5.5 25 5.4 0.2 3.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) Pox_A_type_inc PF04508.12 CDO71266.1 - 2.6 8.0 6.0 9.2 6.3 0.1 4.3 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat T2SSF PF00482.23 CDO71266.1 - 3.2 7.7 5.2 3 7.8 2.6 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F HIP1_clath_bdg PF16515.5 CDO71266.1 - 3.5 8.3 18.6 0.32 11.6 4.1 3.7 2 2 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 CDO71266.1 - 3.8 6.5 20.4 5.7 5.9 5.2 3.1 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliJ PF02050.16 CDO71266.1 - 6.7 7.0 20.3 5 7.4 3.4 3.3 1 1 3 4 4 4 0 Flagellar FliJ protein SlyX PF04102.12 CDO71266.1 - 6.8 7.4 19.3 30 5.3 0.5 5.1 3 1 2 5 5 5 0 SlyX Fib_alpha PF08702.10 CDO71266.1 - 6.9 6.9 12.5 14 5.8 3.9 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 CDO71266.1 - 8.9 6.4 12.0 12 6.0 0.3 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) CK_II_beta PF01214.18 CDO71267.1 - 2.2e-74 249.2 0.0 3.1e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ribosomal_L36e PF01158.18 CDO71267.1 - 5.3e-26 90.7 1.3 5.2e-25 87.5 1.3 2.2 1 1 0 1 1 1 1 Ribosomal protein L36e YL1 PF05764.13 CDO71267.1 - 0.00042 20.5 0.9 0.00042 20.5 0.9 2.1 2 0 0 2 2 2 1 YL1 nuclear protein SNARE_assoc PF09335.11 CDO71268.1 - 3.9e-17 62.8 3.7 3.9e-17 62.8 3.7 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein Cep57_MT_bd PF06657.13 CDO71268.1 - 0.12 12.8 2.0 0.27 11.7 0.6 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PSI_PsaJ PF01701.18 CDO71268.1 - 4.6 7.9 0.0 4.6 7.9 0.0 3.7 4 0 0 4 4 4 0 Photosystem I reaction centre subunit IX / PsaJ CRCB PF02537.15 CDO71269.1 - 1.7e-30 105.1 15.7 3e-18 65.9 4.2 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) adh_short PF00106.25 CDO71270.1 - 6.9e-15 55.0 0.0 9.5e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO71270.1 - 6.2e-08 32.5 0.0 7.9e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Rap1_C PF11626.8 CDO71270.1 - 0.069 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain 60KD_IMP PF02096.20 CDO71272.1 - 1.5e-11 44.5 2.1 2.7e-10 40.4 2.1 2.0 1 1 0 1 1 1 1 60Kd inner membrane protein Bac_rhodopsin PF01036.18 CDO71272.1 - 0.026 14.1 0.3 0.063 12.8 0.3 1.7 1 1 0 1 1 1 0 Bacteriorhodopsin-like protein Seryl_tRNA_N PF02403.22 CDO71272.1 - 0.091 13.0 0.4 0.17 12.1 0.4 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_L6e PF01159.19 CDO71273.1 - 2e-39 134.6 0.1 3e-39 134.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 CDO71273.1 - 0.00013 22.2 0.1 0.00013 22.2 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain Hydrolase PF00702.26 CDO71274.1 - 5.2e-05 23.6 0.0 5.2e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CDO71274.1 - 0.0011 19.1 0.0 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UPF0183 PF03676.14 CDO71275.1 - 2e-12 47.2 0.0 2.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Apt1 PF10351.9 CDO71276.1 - 2.2e-87 293.9 2.5 2.2e-87 293.9 2.5 2.5 3 0 0 3 3 3 1 Golgi-body localisation protein domain DNA_pol_E_B PF04042.16 CDO71276.1 - 6.1e-43 146.6 0.1 1.2e-42 145.7 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Fmp27_WPPW PF10359.9 CDO71276.1 - 9e-41 140.2 0.0 2.1e-30 106.1 0.0 2.5 1 1 1 2 2 2 2 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 CDO71276.1 - 1.1e-39 136.0 0.0 2e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CDO71276.1 - 3e-24 85.7 0.0 1.6e-23 83.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CDO71276.1 - 6.3e-21 75.0 0.0 4.3e-20 72.3 0.0 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DNA_pol_D_N PF18018.1 CDO71276.1 - 0.036 14.2 0.7 0.43 10.7 0.1 2.5 2 0 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain SMP PF04927.12 CDO71276.1 - 5.3 7.6 5.1 13 6.4 5.1 1.6 1 0 0 1 1 1 0 Seed maturation protein Lactonase PF10282.9 CDO71277.1 - 6e-06 25.7 0.0 0.00089 18.6 0.0 2.9 3 0 0 3 3 3 2 Lactonase, 7-bladed beta-propeller DUF2985 PF11204.8 CDO71279.1 - 5.4e-25 87.3 1.3 1.1e-24 86.4 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) OATP PF03137.20 CDO71279.1 - 0.00098 17.5 0.0 0.0015 16.9 0.0 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Clostridium_P47 PF06597.11 CDO71279.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Clostridium P-47 protein SRP72 PF08492.12 CDO71279.1 - 0.043 14.2 1.9 0.52 10.8 0.2 2.7 3 0 0 3 3 3 0 SRP72 RNA-binding domain Phage_holin_3_6 PF07332.11 CDO71279.1 - 0.15 12.1 0.2 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Meth_synt_2 PF01717.18 CDO71280.1 - 2.6e-152 506.8 0.0 2.2e-148 493.8 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CDO71280.1 - 8e-117 390.2 0.0 3.2e-109 365.2 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 CDO71280.1 - 0.026 14.3 6.9 0.04 13.7 1.2 2.8 2 0 0 2 2 2 0 Short C-terminal domain ADH_N PF08240.12 CDO71281.1 - 7.8e-31 106.2 0.3 1.2e-30 105.6 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO71281.1 - 5e-21 75.0 0.0 7.1e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO71281.1 - 1.1e-05 26.4 0.0 1.9e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TmoB PF06234.12 CDO71281.1 - 0.087 12.9 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) Gly_transf_sug PF04488.15 CDO71282.1 - 5.2e-22 78.3 0.1 1e-21 77.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 CDO71282.1 - 0.042 13.2 1.1 0.25 10.6 0.0 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 CDO71282.1 - 0.12 11.7 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein CLLAC PF15675.5 CDO71282.1 - 0.67 9.6 4.5 1.6 8.4 4.5 1.6 1 0 0 1 1 1 0 CLLAC-motif containing domain PIN_4 PF13638.6 CDO71283.1 - 1.3e-19 70.8 0.0 2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 PIN domain CTD_bind PF04818.13 CDO71284.1 - 8.4e-05 23.3 0.0 0.00022 22.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 CDO71284.1 - 0.0028 18.1 0.5 0.018 15.5 0.0 2.5 2 1 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 Zn-C2H2_12 PF18112.1 CDO71284.1 - 0.0037 17.7 5.6 0.024 15.1 0.9 2.5 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 CDO71284.1 - 0.6 11.1 3.9 1.7 9.7 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_L6 PF00347.23 CDO71285.1 - 6.6e-29 100.4 4.8 6.3e-16 58.8 1.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 ICMT PF04140.14 CDO71286.1 - 2.2e-27 95.3 1.0 4.6e-27 94.3 1.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO71286.1 - 5.9e-12 45.9 1.2 1.4e-11 44.7 1.2 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.11 CDO71286.1 - 3.8e-06 26.6 2.3 6.6e-06 25.8 2.3 1.4 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.12 CDO71286.1 - 0.0038 16.8 1.0 0.0061 16.1 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GTP_EFTU PF00009.27 CDO71287.1 - 1.5e-50 171.5 0.0 2.3e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CDO71287.1 - 1.8e-15 56.7 0.0 4.5e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CDO71287.1 - 8.2e-15 54.6 0.0 5.5e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDO71287.1 - 3.9e-06 27.2 0.0 7.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDO71287.1 - 8.4e-05 22.6 0.0 0.00023 21.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 CDO71287.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain AIG1 PF04548.16 CDO71287.1 - 0.16 11.3 0.0 0.54 9.5 0.0 1.8 1 1 0 1 1 1 0 AIG1 family MFS_1 PF07690.16 CDO71289.1 - 9.5e-33 113.6 17.0 9.6e-30 103.7 15.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 CDO71289.1 - 0.00048 19.2 0.5 0.00097 18.2 0.5 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 CDO71289.1 - 0.0074 14.8 2.3 0.012 14.1 2.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Stevor PF17410.2 CDO71289.1 - 0.26 10.8 0.4 1.2 8.6 0.1 2.0 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame TruD PF01142.18 CDO71290.1 - 2e-75 254.2 0.0 1.1e-67 228.7 0.1 3.3 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) FoP_duplication PF13865.6 CDO71290.1 - 1.6 9.3 9.0 8.8 7.0 5.6 2.8 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 OMPdecase PF00215.24 CDO71291.1 - 2.2e-73 246.6 0.0 2.8e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family eRF1_1 PF03463.15 CDO71292.1 - 4e-43 146.5 0.0 6.2e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 CDO71292.1 - 2.3e-22 79.6 0.0 4.7e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 CDO71292.1 - 6e-19 68.7 0.0 9.2e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 tRNA_anti-codon PF01336.25 CDO71292.1 - 0.14 12.2 0.0 0.75 9.8 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Thioredoxin PF00085.20 CDO71293.1 - 0.0023 17.9 0.1 0.0044 17.0 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Calc_CGRP_IAPP PF00214.19 CDO71293.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family FAD_binding_7 PF03441.14 CDO71294.1 - 8.7e-70 234.3 2.2 2.6e-69 232.8 1.5 1.9 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CDO71294.1 - 6.9e-27 94.5 0.4 5e-13 49.4 0.0 2.4 1 1 1 2 2 2 2 DNA photolyase DUF5127 PF17168.4 CDO71295.1 - 7.1e-83 277.8 5.4 7.1e-83 277.8 5.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 CDO71295.1 - 1.3e-73 246.4 0.1 4.7e-73 244.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 CDO71295.1 - 1.5e-66 224.0 2.0 1.5e-66 224.0 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 CDO71296.1 - 3.2e-66 222.3 0.3 3.2e-66 222.3 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 CDO71296.1 - 1.2e-47 162.4 4.3 4.2e-47 160.7 4.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1793) Invasin_D3 PF09134.10 CDO71296.1 - 0.011 16.0 3.7 0.029 14.7 3.7 1.7 1 0 0 1 1 1 0 Invasin, domain 3 DUF4851 PF16143.5 CDO71296.1 - 0.57 9.6 5.4 4.5 6.7 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4851) Wtap PF17098.5 CDO71297.1 - 2e-20 73.3 8.0 2.2e-15 56.9 3.1 2.2 1 1 1 2 2 2 2 WTAP/Mum2p family PRP38_assoc PF12871.7 CDO71297.1 - 0.023 15.3 21.8 0.064 13.9 21.8 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SKA1 PF07160.12 CDO71297.1 - 0.055 13.3 0.7 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 MOZART2 PF12926.7 CDO71297.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated PKcGMP_CC PF16808.5 CDO71297.1 - 0.2 11.5 3.0 5.4 7.0 0.6 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3915 PF13054.6 CDO71297.1 - 0.26 11.3 2.3 0.44 10.5 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) TMF_DNA_bd PF12329.8 CDO71297.1 - 0.39 10.7 7.3 3.3 7.8 0.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 CDO71297.1 - 0.67 10.5 4.2 2.1 8.9 4.2 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region FliJ PF02050.16 CDO71297.1 - 2.2 8.5 7.8 0.13 12.5 2.2 1.7 2 0 0 2 2 2 0 Flagellar FliJ protein Glyco_hydro_18 PF00704.28 CDO71299.1 - 0.0091 15.8 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Myb_DNA-bind_2 PF08914.11 CDO71301.1 - 0.0054 16.9 0.7 0.062 13.5 0.4 2.4 2 0 0 2 2 2 1 Rap1 Myb domain PBP_N PF17093.5 CDO71301.1 - 0.055 13.7 3.8 0.06 13.6 1.8 2.0 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus ThiF PF00899.21 CDO71302.1 - 2.1e-113 377.7 0.0 1.5e-72 243.9 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CDO71302.1 - 4.6e-93 311.8 0.2 7e-93 311.2 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 CDO71302.1 - 2.7e-37 126.8 0.8 5.9e-37 125.7 0.8 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CDO71302.1 - 3.2e-28 97.7 3.3 4.1e-28 97.4 1.2 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 CDO71302.1 - 1.7e-18 67.1 0.6 5.5e-11 43.0 0.2 2.7 1 1 1 2 2 2 2 Ubiquitin fold domain End_beta_barrel PF12195.8 CDO71302.1 - 0.2 11.6 0.1 3.1 7.8 0.0 2.4 1 1 1 2 2 2 0 Beta barrel domain of bacteriophage endosialidase Diphthami_syn_2 PF01902.17 CDO71303.1 - 1.9e-32 112.5 0.0 3.3e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CDO71303.1 - 2.7e-21 75.8 0.0 3.2e-10 40.1 0.0 2.8 2 1 0 2 2 2 2 Endoribonuclease L-PSP MFS_1 PF07690.16 CDO71304.1 - 2.5e-11 43.1 25.3 1.8e-10 40.3 23.7 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CDO71304.1 - 0.0013 17.7 0.0 0.96 8.2 0.3 3.1 2 2 1 3 3 3 2 MFS_1 like family Spore_YhaL PF14147.6 CDO71304.1 - 0.16 11.7 1.2 7.2 6.4 0.0 2.8 2 0 0 2 2 2 0 Sporulation protein YhaL Ank_4 PF13637.6 CDO71305.1 - 3.8e-23 81.5 1.0 5.4e-12 46.0 0.1 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDO71305.1 - 7.2e-22 77.8 0.1 8.1e-15 55.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDO71305.1 - 2.4e-17 62.8 0.5 1.2e-08 35.1 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDO71305.1 - 1.1e-13 50.0 0.1 0.00018 21.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CDO71305.1 - 3.1e-12 46.3 0.1 7.2e-05 23.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat zf-Mss51 PF13824.6 CDO71306.1 - 0.033 14.3 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Cyclin PF08613.11 CDO71307.1 - 0.00012 22.5 0.0 0.00019 21.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin DUF3402 PF11882.8 CDO71308.1 - 5.9e-114 381.7 0.0 1.8e-66 225.2 0.0 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 CDO71308.1 - 1.9e-60 204.5 3.6 1.2e-38 132.9 2.9 2.3 1 1 1 2 2 2 2 N1221-like protein Diphthamide_syn PF01866.17 CDO71309.1 - 1.6e-92 310.2 0.0 4.9e-53 180.5 0.0 2.9 1 1 0 2 2 2 2 Putative diphthamide synthesis protein NPC1_N PF16414.5 CDO71310.1 - 4.5e-81 272.0 6.0 6.5e-81 271.5 6.0 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 CDO71310.1 - 2.4e-63 214.5 9.7 7.5e-35 120.3 0.3 3.7 3 1 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 CDO71310.1 - 3.4e-45 153.6 15.9 1.9e-24 86.2 0.2 3.5 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 CDO71310.1 - 6.1e-05 20.9 4.7 6.1e-05 20.9 4.7 1.7 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Folate_rec PF03024.14 CDO71310.1 - 0.00038 20.4 0.6 0.00077 19.4 0.6 1.4 1 0 0 1 1 1 1 Folate receptor family RNR_inhib PF08591.10 CDO71311.1 - 1.3e-07 32.9 0.7 1.6e-06 29.4 0.2 2.2 1 1 1 2 2 2 1 Ribonucleotide reductase inhibitor zf-C2H2 PF00096.26 CDO71312.1 - 0.007 16.8 1.1 0.007 16.8 1.1 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO71312.1 - 0.043 14.7 15.6 1.4 10.0 2.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDO71312.1 - 0.2 12.1 17.0 4 8.0 3.9 3.8 3 0 0 3 3 3 0 Zinc-finger double domain CIAPIN1 PF05093.13 CDO71313.1 - 1.8e-31 108.6 4.1 2.9e-31 107.9 4.1 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 CDO71313.1 - 8.5e-07 29.3 0.0 1.4e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus FoP_duplication PF13865.6 CDO71314.1 - 0.022 15.3 3.3 0.054 14.1 3.3 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Forkhead PF00250.18 CDO71316.1 - 9.3e-31 105.9 0.0 1.4e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Forkhead domain Tim17 PF02466.19 CDO71317.1 - 0.044 14.2 3.6 0.083 13.3 2.7 1.9 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family SCF PF02404.15 CDO71317.1 - 0.19 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Stem cell factor Pkinase PF00069.25 CDO71318.1 - 7e-63 212.5 0.2 1.3e-62 211.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71318.1 - 1.3e-28 100.0 0.0 2.2e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CDO71318.1 - 1.5e-16 60.8 0.5 1.5e-16 60.8 0.5 3.2 3 1 0 3 3 3 1 Protein kinase C terminal domain C2 PF00168.30 CDO71318.1 - 2.4e-12 47.1 0.1 1.7e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 CDO71318.1 - 8.5e-07 28.2 0.0 1.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDO71318.1 - 2.9e-06 26.8 0.1 1.9e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDO71318.1 - 0.025 14.5 1.7 0.032 14.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CDO71318.1 - 0.032 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDO71318.1 - 0.073 12.6 0.0 0.073 12.6 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase FTA2 PF13095.6 CDO71318.1 - 0.091 12.4 7.0 0.32 10.6 0.1 3.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CDO71318.1 - 0.099 11.4 3.3 0.21 10.3 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase Presenilin PF01080.17 CDO71318.1 - 9.9 4.8 9.8 16 4.1 9.8 1.3 1 0 0 1 1 1 0 Presenilin Suc_Fer-like PF06999.12 CDO71319.1 - 1.5e-25 90.2 0.0 2.2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF2271 PF10029.9 CDO71319.1 - 0.066 12.9 0.1 0.58 9.8 0.0 2.1 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2271) APH PF01636.23 CDO71320.1 - 0.009 16.0 0.1 0.009 16.0 0.1 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 CDO71321.1 - 5.7e-61 206.2 0.0 1.5e-40 139.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71321.1 - 1.4e-28 99.9 0.0 4.5e-23 81.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 CDO71321.1 - 8.8e-14 51.6 0.0 1.7e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 CDO71321.1 - 1.5e-08 34.3 0.1 0.001 18.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDO71321.1 - 0.00071 19.6 0.0 0.0026 17.7 0.0 2.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDO71321.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CDO71321.1 - 0.0096 15.6 0.0 0.83 9.2 0.0 2.4 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CDO71321.1 - 0.012 14.5 0.0 0.029 13.3 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain PAS_9 PF13426.7 CDO71321.1 - 0.089 13.1 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 PAS domain RIO1 PF01163.22 CDO71321.1 - 0.13 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 CDO71321.1 - 0.18 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UIM PF02809.20 CDO71321.1 - 0.6 10.2 3.8 3.5 7.8 3.8 2.5 1 0 0 1 1 1 0 Ubiquitin interaction motif Ribosomal_S18 PF01084.20 CDO71322.1 - 2.1e-13 50.3 0.2 3.7e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 JAB PF01398.21 CDO71323.1 - 1.4e-32 112.2 0.4 2.2e-32 111.5 0.4 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDO71323.1 - 1.5e-14 54.4 0.8 2.9e-14 53.5 0.8 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CDO71323.1 - 2.1e-07 30.7 0.0 3.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 CDO71323.1 - 0.027 14.6 0.1 0.066 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) FMO-like PF00743.19 CDO71325.1 - 2.8e-23 82.2 0.0 9.7e-23 80.4 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CDO71325.1 - 1.2e-18 67.5 0.0 6.3e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDO71325.1 - 2e-14 53.6 0.0 2.2e-10 40.3 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDO71325.1 - 1.9e-10 40.4 0.0 1.7e-09 37.3 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 CDO71325.1 - 2e-06 28.3 0.3 0.28 11.8 0.1 3.4 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO71325.1 - 0.00089 19.3 0.0 0.13 12.3 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 CDO71325.1 - 0.0018 18.3 0.0 0.034 14.2 0.0 2.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 CDO71325.1 - 0.0043 16.3 0.0 0.26 10.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 CDO71325.1 - 0.018 15.3 0.1 0.75 10.1 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.6 CDO71325.1 - 0.061 13.6 0.1 0.3 11.3 0.0 2.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CDO71325.1 - 0.075 12.1 0.1 24 3.8 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 CDO71325.1 - 0.14 11.2 0.0 7.7 5.5 0.0 2.9 3 1 0 3 3 3 0 Glucose inhibited division protein A FMO-like PF00743.19 CDO71326.1 - 1e-23 83.6 0.0 5.1e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CDO71326.1 - 2.4e-12 46.7 0.0 3.2e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDO71326.1 - 1.9e-10 40.5 0.0 3e-06 26.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDO71326.1 - 5.5e-08 32.3 0.0 7.2e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 CDO71326.1 - 0.0029 17.7 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Vps52 PF04129.12 CDO71327.1 - 1.7e-40 139.3 0.1 1.6e-14 53.5 0.0 3.0 3 0 0 3 3 3 3 Vps52 / Sac2 family BRCT_2 PF16589.5 CDO71329.1 - 4.5e-09 36.6 0.0 8.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CDO71329.1 - 5.7e-07 29.8 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 CDO71329.1 - 6.2e-05 22.8 0.1 0.00014 21.7 0.0 1.7 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 CDO71329.1 - 0.0003 21.0 0.1 0.00051 20.3 0.1 1.4 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 CDO71329.1 - 0.014 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Ribophorin_I PF04597.14 CDO71331.1 - 1.2e-103 347.7 0.1 1e-94 318.2 0.0 2.2 1 1 1 2 2 2 2 Ribophorin I Ribosomal_L22 PF00237.19 CDO71331.1 - 6.7e-22 77.7 0.8 1.2e-21 76.9 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e GILT PF03227.16 CDO71332.1 - 7.7e-18 64.7 1.7 9.2e-18 64.5 0.1 1.8 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_5 PF13743.6 CDO71332.1 - 0.18 11.5 0.0 0.75 9.5 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin Cid2 PF09774.9 CDO71333.1 - 6.2e-20 72.2 0.7 7e-20 72.1 0.7 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Ntox35 PF15534.6 CDO71333.1 - 0.075 13.5 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 35 ERM PF00769.19 CDO71334.1 - 0.064 13.1 0.0 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Kelch_4 PF13418.6 CDO71335.1 - 6.7e-16 58.0 10.0 0.0002 21.3 0.1 6.7 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CDO71335.1 - 8.1e-12 45.1 13.1 0.00065 19.9 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CDO71335.1 - 6.5e-09 35.8 0.4 0.11 12.8 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CDO71335.1 - 1.8e-05 24.2 1.8 3 7.5 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 CDO71335.1 - 1.9e-05 24.5 2.0 0.22 11.6 0.1 4.6 4 0 0 4 4 4 2 Kelch motif Cytochrom_B561 PF03188.16 CDO71335.1 - 2.9 8.0 6.2 3.2 7.9 0.5 2.3 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 RAP1 PF07218.11 CDO71335.1 - 7.3 4.7 8.2 10 4.3 8.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SPESP1 PF15754.5 CDO71336.1 - 0.11 11.6 0.6 0.28 10.3 0.6 1.6 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 HSP90 PF00183.18 CDO71337.1 - 1.4e-131 439.9 2.5 1.8e-131 439.6 2.5 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 CDO71337.1 - 8.7e-11 41.8 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CDO71337.1 - 6.4e-09 36.3 0.0 1.4e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5347 PF17282.2 CDO71337.1 - 0.032 14.5 0.2 2.2 8.6 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5347) COMPASS-Shg1 PF05205.12 CDO71337.1 - 0.049 14.4 0.0 1 10.1 0.0 2.6 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 SSF PF00474.17 CDO71338.1 - 3.1e-24 85.6 17.3 5.8e-24 84.7 17.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family FF PF01846.19 CDO71339.1 - 3.6e-40 135.9 20.8 5.8e-11 42.4 0.0 6.4 6 0 0 6 6 6 5 FF domain WW PF00397.26 CDO71339.1 - 3.5e-09 36.6 21.0 1.2e-08 34.9 3.4 3.5 3 0 0 3 3 3 2 WW domain RhoGAP-FF1 PF16512.5 CDO71339.1 - 9.6e-05 23.0 9.9 0.68 10.6 2.4 5.3 4 2 1 5 5 5 2 p190-A and -B Rho GAPs FF domain GREB1 PF15782.5 CDO71339.1 - 5.8 3.9 11.2 8.7 3.3 11.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Peroxidase_2 PF01328.17 CDO71340.1 - 3e-53 181.2 0.0 3.6e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 MFS_1 PF07690.16 CDO71341.1 - 7e-28 97.6 24.0 7.2e-27 94.2 24.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily RasGAP_C PF03836.15 CDO71342.1 - 1.5e-45 154.7 2.9 1.5e-45 154.7 2.9 2.5 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 CDO71342.1 - 6.6e-42 143.6 0.0 1.5e-41 142.4 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 CDO71342.1 - 8.8e-19 65.5 67.2 0.0024 17.5 0.3 13.9 13 0 0 13 13 13 10 IQ calmodulin-binding motif CH PF00307.31 CDO71342.1 - 2.4e-13 50.2 0.0 6.4e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain Sipho_Gp157 PF05565.11 CDO71342.1 - 0.95 9.5 6.9 0.14 12.2 0.9 2.6 2 0 0 2 2 2 0 Siphovirus Gp157 Hamartin PF04388.12 CDO71342.1 - 3.6 6.1 17.2 8.1 5.0 17.2 1.5 1 0 0 1 1 1 0 Hamartin protein GCP_C_terminal PF04130.13 CDO71343.1 - 1.7e-91 306.9 0.9 3.4e-91 305.9 0.9 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CDO71343.1 - 2.1e-68 231.2 0.0 2.1e-62 211.5 0.0 3.4 1 1 1 2 2 2 2 Gamma tubulin complex component N-terminal E1-E2_ATPase PF00122.20 CDO71344.1 - 4.3e-47 160.0 2.2 2.6e-46 157.4 0.8 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CDO71344.1 - 4.6e-32 112.0 0.4 1.2e-31 110.7 0.4 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CDO71344.1 - 1.2e-12 48.1 0.2 1.2e-09 38.5 0.0 3.2 3 1 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CDO71344.1 - 0.00041 20.2 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E7 PF00527.18 CDO71344.1 - 0.37 11.0 1.5 1.1 9.5 1.2 1.9 1 1 0 1 1 1 0 E7 protein, Early protein DUF485 PF04341.12 CDO71344.1 - 6.2 6.8 11.3 1.2 9.1 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF485 DUF4149 PF13664.6 CDO71344.1 - 6.8 7.1 7.1 0.6 10.5 0.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) E1-E2_ATPase PF00122.20 CDO71345.1 - 3e-46 157.2 0.2 3e-46 157.2 0.2 3.7 5 0 0 5 5 5 1 E1-E2 ATPase HMA PF00403.26 CDO71345.1 - 1.1e-43 147.5 1.9 1.1e-12 48.2 0.1 5.2 4 1 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 CDO71345.1 - 2.5e-35 122.7 0.2 5.1e-35 121.7 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CDO71345.1 - 0.00038 20.3 0.1 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SNAD4 PF18750.1 CDO71345.1 - 0.012 15.8 0.1 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 4 HAD PF12710.7 CDO71345.1 - 0.076 13.4 0.0 0.29 11.5 0.0 2.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase APOBEC1 PF18769.1 CDO71345.1 - 0.1 12.8 0.1 47 4.3 0.0 3.3 3 0 0 3 3 3 0 APOBEC1 HscB_4_cys PF18256.1 CDO71345.1 - 1.2 9.0 3.5 16 5.4 0.2 2.7 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Fer2_BFD PF04324.15 CDO71345.1 - 3.8 8.0 8.0 30 5.1 0.0 4.3 5 0 0 5 5 5 0 BFD-like [2Fe-2S] binding domain His_Phos_2 PF00328.22 CDO71346.1 - 2e-89 300.6 0.1 3.1e-89 300.0 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CDO71346.1 - 1.6e-33 114.7 0.0 3.5e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CDO71346.1 - 1.8e-06 27.7 0.0 3.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain FSIP1 PF15554.6 CDO71346.1 - 0.027 13.6 0.2 0.041 13.0 0.2 1.2 1 0 0 1 1 1 0 FSIP1 family UQ_con PF00179.26 CDO71347.1 - 3e-14 52.9 0.1 4.6e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AAA_14 PF13173.6 CDO71347.1 - 0.0031 17.5 0.2 1.4 8.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain RWD PF05773.22 CDO71347.1 - 0.042 14.1 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain HIG_1_N PF04588.13 CDO71348.1 - 6.6e-06 26.2 3.1 1.6e-05 25.0 3.1 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2162 PF09930.9 CDO71348.1 - 0.021 14.3 0.3 0.032 13.6 0.3 1.2 1 0 0 1 1 1 0 Predicted transporter (DUF2162) DUF1944 PF09175.10 CDO71348.1 - 0.084 12.7 1.2 0.13 12.1 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) Ferric_reduct PF01794.19 CDO71349.1 - 1.3e-21 77.0 2.6 1.3e-21 77.0 2.6 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CDO71349.1 - 7.4e-11 42.4 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CDO71349.1 - 1.2e-09 38.2 0.0 2.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CDO71349.1 - 0.0016 19.1 0.0 0.0031 18.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PgaD PF13994.6 CDO71349.1 - 0.056 13.5 0.7 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 PgaD-like protein NAD_binding_6 PF08030.12 CDO71350.1 - 1.2e-17 64.4 0.0 1.8e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 CDO71350.1 - 2.1e-16 60.2 8.5 6.2e-16 58.7 8.5 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CDO71350.1 - 1.6e-09 37.8 0.0 3.9e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CDO71350.1 - 2.2e-05 25.0 0.0 5.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MIG-14_Wnt-bd PF06664.12 CDO71350.1 - 0.0043 16.3 1.9 0.01 15.1 1.9 1.6 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion RRM_1 PF00076.22 CDO71351.1 - 1.7e-20 72.6 0.0 1.2e-09 37.8 0.0 3.7 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDO71351.1 - 0.019 15.0 0.2 0.088 12.8 0.1 2.1 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif Hid1 PF12722.7 CDO71351.1 - 4.8 5.2 9.3 8 4.5 9.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ofd1_CTDD PF10637.9 CDO71352.1 - 5.9e-45 153.6 0.0 3.5e-37 128.1 0.0 3.2 2 1 1 3 3 3 3 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CDO71352.1 - 9.3e-31 106.4 0.0 3.4e-30 104.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CDO71352.1 - 5.6e-15 56.0 0.1 2.4e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily UL42 PF17638.2 CDO71353.1 - 0.028 14.4 0.0 0.028 14.4 0.0 2.7 2 1 1 3 3 3 0 HCMV UL42 SelP_N PF04592.14 CDO71353.1 - 0.55 9.6 7.9 0.95 8.8 7.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HIG_1_N PF04588.13 CDO71354.1 - 5.8e-05 23.2 0.1 0.00013 22.2 0.1 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3561 PF12084.8 CDO71354.1 - 0.095 12.7 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) Abhydrolase_1 PF00561.20 CDO71355.1 - 2.1e-20 73.5 0.3 6e-19 68.7 0.4 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO71355.1 - 4.9e-18 66.5 0.4 6.9e-18 66.1 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO71355.1 - 7e-10 38.6 0.1 3.8e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 CDO71355.1 - 0.097 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 CDO71355.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme AAA_13 PF13166.6 CDO71356.1 - 0.034 12.8 5.6 0.056 12.1 5.6 1.2 1 0 0 1 1 1 0 AAA domain DUF1690 PF07956.11 CDO71356.1 - 0.096 13.1 11.1 1.2 9.5 7.7 3.0 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) Fmp27_WPPW PF10359.9 CDO71356.1 - 0.12 11.2 5.5 0.042 12.7 3.0 1.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.11 CDO71356.1 - 0.15 10.9 16.9 0.017 14.0 11.3 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein ZapB PF06005.12 CDO71356.1 - 0.22 12.0 27.7 0.035 14.6 8.8 3.6 2 1 1 3 3 3 0 Cell division protein ZapB Uso1_p115_C PF04871.13 CDO71356.1 - 0.39 11.1 18.7 0.32 11.4 13.8 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MCU PF04678.13 CDO71356.1 - 1.2 9.3 5.6 0.21 11.7 1.6 1.8 2 0 0 2 2 2 0 Mitochondrial calcium uniporter FapA PF03961.13 CDO71356.1 - 1.3 7.5 5.1 2.3 6.7 5.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 CDO71356.1 - 1.5 6.7 4.2 2.6 5.9 4.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.6 CDO71356.1 - 6.3 6.9 16.8 0.047 13.7 7.5 2.1 2 0 0 2 2 2 0 FlxA-like protein Cyt-b5 PF00173.28 CDO71358.1 - 6.2e-24 83.9 0.1 8.3e-24 83.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sedlin_N PF04628.13 CDO71359.1 - 2.6e-19 69.6 0.1 3.6e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RTP1_C1 PF10363.9 CDO71360.1 - 3.3e-35 120.6 0.1 2.9e-34 117.6 0.0 2.7 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 CDO71360.1 - 0.00099 18.7 0.3 0.0027 17.3 0.3 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 zf-RING_2 PF13639.6 CDO71361.1 - 1.1e-06 28.9 10.6 2.1e-06 27.9 10.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CDO71361.1 - 5.8e-05 23.0 10.2 0.00011 22.0 10.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDO71361.1 - 0.00014 21.8 6.7 0.00037 20.5 6.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDO71361.1 - 0.00041 20.2 11.1 0.00084 19.2 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDO71361.1 - 0.0047 16.7 9.4 0.0098 15.7 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDO71361.1 - 0.009 15.9 9.0 0.019 14.8 9.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CDO71361.1 - 0.021 14.6 8.3 0.049 13.4 8.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger Striatin PF08232.12 CDO71361.1 - 0.021 15.4 7.0 0.045 14.3 7.0 1.6 1 0 0 1 1 1 0 Striatin family zf-C3HC4_2 PF13923.6 CDO71361.1 - 0.061 13.2 10.5 0.18 11.7 10.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDO71361.1 - 0.085 13.0 10.8 0.22 11.7 10.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ERM PF00769.19 CDO71361.1 - 1.9 8.2 14.5 4.9 6.9 14.4 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family GTP_EFTU PF00009.27 CDO71362.1 - 1.9e-46 158.1 0.0 3.3e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDO71362.1 - 5.8e-35 120.0 0.1 3.3e-34 117.5 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDO71362.1 - 9.7e-12 45.1 0.3 2.4e-11 43.9 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDO71362.1 - 0.0019 18.3 0.1 0.016 15.3 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.15 CDO71362.1 - 0.0041 16.7 0.4 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Ataxin-2 C-terminal region Ndc1_Nup PF09531.10 CDO71362.1 - 0.2 10.3 2.0 0.27 9.9 2.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SH3_9 PF14604.6 CDO71363.1 - 1.2e-37 127.5 8.5 4.3e-14 52.1 0.4 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 CDO71363.1 - 1.8e-37 126.7 4.9 4.2e-15 55.1 0.1 4.2 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.17 CDO71363.1 - 9.5e-28 95.7 0.2 1.4e-09 37.4 0.0 4.5 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.11 CDO71363.1 - 4.1e-07 30.2 5.1 0.016 15.5 0.5 3.6 3 0 0 3 3 3 2 Bacterial SH3 domain hSH3 PF14603.6 CDO71363.1 - 1.9e-06 28.2 0.0 0.02 15.3 0.0 2.6 2 0 0 2 2 2 2 Helically-extended SH3 domain SH3_10 PF17902.1 CDO71363.1 - 2.9e-05 24.1 0.2 0.13 12.4 0.0 3.6 2 1 1 3 3 3 1 SH3 domain SHD1 PF03983.12 CDO71363.1 - 0.00011 21.9 0.1 0.00033 20.4 0.1 1.8 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SAM_4 PF18017.1 CDO71363.1 - 0.00022 21.1 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Macoilin PF09726.9 CDO71363.1 - 3.1 6.2 15.9 5.5 5.4 15.9 1.3 1 0 0 1 1 1 0 Macoilin family Sec7 PF01369.20 CDO71364.1 - 7.4e-72 240.9 0.1 1.6e-71 239.8 0.1 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CDO71364.1 - 3.7e-45 153.7 4.3 3.7e-45 153.7 4.3 3.7 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CDO71364.1 - 1.5e-34 117.7 10.7 5.3e-34 115.9 0.1 5.6 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 CDO71364.1 - 1.6e-21 76.8 6.7 2.5e-20 72.9 0.1 3.7 4 0 0 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 HEAT PF02985.22 CDO71364.1 - 0.0094 16.1 0.7 1.2 9.6 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat DUF1539 PF07560.11 CDO71364.1 - 0.071 13.2 1.1 5.8 7.0 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) DS PF01916.17 CDO71365.1 - 1.5e-138 460.9 0.0 1.7e-138 460.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase 14-3-3 PF00244.20 CDO71366.1 - 5.7e-74 248.4 1.7 6.4e-74 248.2 1.7 1.0 1 0 0 1 1 1 1 14-3-3 protein Glyco_hydro_61 PF03443.14 CDO71367.1 - 4.4e-53 180.3 0.2 5.2e-53 180.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aldo_ket_red PF00248.21 CDO71368.1 - 2e-44 152.0 0.0 3.3e-42 144.7 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Imm12 PF15560.6 CDO71368.1 - 0.17 11.8 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 12 DUF2052 PF09747.9 CDO71369.1 - 0.00014 22.1 22.0 0.0019 18.4 22.0 2.2 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Nucleo_P87 PF07267.11 CDO71369.1 - 0.028 13.3 0.5 0.034 13.0 0.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Abhydrolase_6 PF12697.7 CDO71370.1 - 2.7e-06 28.1 1.6 3.7e-06 27.7 1.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CDO71370.1 - 0.0017 18.2 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 CDO71370.1 - 0.0023 17.6 0.0 0.0087 15.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO71370.1 - 0.0024 17.2 0.0 0.005 16.1 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 CDO71370.1 - 0.0068 15.9 0.0 0.093 12.2 0.0 2.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CDO71370.1 - 0.012 15.4 0.0 0.033 13.9 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_3 PF07859.13 CDO71370.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.11 CDO71370.1 - 0.032 13.6 0.1 0.26 10.6 0.1 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 CDO71370.1 - 0.15 11.6 0.1 1 8.8 0.1 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) F-box-like PF12937.7 CDO71371.1 - 1.9e-12 46.9 2.5 6.4e-12 45.2 2.5 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CDO71371.1 - 2.4e-10 40.5 13.5 0.087 13.3 0.0 7.5 6 2 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDO71371.1 - 6e-07 29.0 13.4 1.8 8.8 0.1 9.3 10 0 0 10 10 10 3 Leucine Rich repeat F-box PF00646.33 CDO71371.1 - 5.5e-05 22.9 0.3 0.00073 19.3 0.5 2.8 2 0 0 2 2 2 1 F-box domain YL1 PF05764.13 CDO71371.1 - 0.038 14.1 0.2 0.06 13.5 0.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF4050 PF13259.6 CDO71372.1 - 0.00085 19.7 0.1 0.0071 16.7 0.0 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF4050) LSM PF01423.22 CDO71373.1 - 1.6e-19 69.3 0.4 1.9e-19 69.1 0.4 1.1 1 0 0 1 1 1 1 LSM domain zf-U1 PF06220.12 CDO71374.1 - 1.8e-20 72.4 4.1 2.5e-20 71.9 4.1 1.2 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 CDO71374.1 - 0.12 12.3 1.5 0.19 11.7 1.5 1.3 1 0 0 1 1 1 0 CLIP1 zinc knuckle Sua5_yciO_yrdC PF01300.18 CDO71375.1 - 1.8e-51 174.2 0.0 4.1e-51 173.0 0.0 1.6 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 CDO71375.1 - 5.9e-29 101.3 0.0 9e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding HMG_box PF00505.19 CDO71376.1 - 1.4e-11 44.7 1.9 3.9e-11 43.2 1.9 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO71376.1 - 0.002 18.7 0.0 0.0042 17.7 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 CDO71376.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box DEAD PF00270.29 CDO71377.1 - 2.1e-25 89.5 0.0 2.2e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO71377.1 - 3.9e-25 88.3 0.0 1.8e-23 83.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Nop14 PF04147.12 CDO71377.1 - 0.012 13.9 6.5 0.021 13.1 6.5 1.4 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 CDO71377.1 - 0.75 10.1 7.9 2.4 8.5 3.1 2.9 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Mob1_phocein PF03637.17 CDO71379.1 - 1.4e-57 194.4 0.0 1.1e-50 172.0 0.0 2.0 1 1 1 2 2 2 2 Mob1/phocein family DJ-1_PfpI PF01965.24 CDO71380.1 - 5.9e-14 52.2 0.0 1.2e-13 51.3 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CDO71380.1 - 0.00042 20.1 0.0 0.017 14.8 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like RRM_1 PF00076.22 CDO71381.1 - 5.4e-19 67.8 0.0 5.1e-08 32.6 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDO71381.1 - 0.00024 20.7 0.0 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDO71381.1 - 0.0012 18.6 0.0 0.045 13.6 0.0 2.4 2 1 0 2 2 2 1 Occluded RNA-recognition motif Rib_recp_KP_reg PF05104.12 CDO71381.1 - 0.029 15.4 1.6 0.043 14.9 1.6 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region MCM_bind PF09739.9 CDO71381.1 - 0.12 10.8 0.6 0.15 10.5 0.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4666 PF15697.5 CDO71381.1 - 0.5 11.1 2.9 0.89 10.3 2.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4666) DNA_pol_phi PF04931.13 CDO71381.1 - 0.51 8.4 7.8 0.67 8.0 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 CDO71381.1 - 0.52 9.5 2.9 0.72 9.0 2.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TRAM_LAG1_CLN8 PF03798.16 CDO71382.1 - 8.6e-49 166.0 26.0 1.1e-48 165.6 26.0 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 CDO71382.1 - 5.4e-09 35.6 0.0 5.4e-09 35.6 0.0 3.3 4 0 0 4 4 4 1 TRAM1-like protein Snf7 PF03357.21 CDO71383.1 - 2.5e-26 92.3 29.8 2.4e-14 53.3 13.6 2.4 3 0 0 3 3 3 2 Snf7 DUF3138 PF11336.8 CDO71383.1 - 0.092 11.3 0.5 0.15 10.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SOGA PF11365.8 CDO71383.1 - 6.2 8.0 14.6 1.1 10.5 0.1 3.1 3 1 0 3 3 3 0 Protein SOGA NIF PF03031.18 CDO71384.1 - 1.2e-52 177.8 0.0 1.8e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MFS_1 PF07690.16 CDO71384.1 - 7.4e-38 130.4 33.1 7.5e-33 113.9 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_UBOX PF13445.6 CDO71385.1 - 1.4e-05 25.0 2.7 3.1e-05 23.9 0.0 2.5 3 1 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDO71385.1 - 0.00079 19.3 0.3 0.029 14.2 0.3 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO71385.1 - 0.0058 16.9 10.9 3.4 8.1 0.1 3.3 2 1 1 3 3 3 3 Ring finger domain Prok-RING_4 PF14447.6 CDO71385.1 - 0.0067 16.3 5.3 0.37 10.7 0.1 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CDO71385.1 - 0.018 15.0 5.8 0.59 10.1 6.1 2.9 1 1 0 1 1 1 0 zinc-RING finger domain NOA36 PF06524.12 CDO71385.1 - 0.032 13.6 3.6 0.044 13.1 3.6 1.2 1 0 0 1 1 1 0 NOA36 protein zf-rbx1 PF12678.7 CDO71385.1 - 0.39 11.0 4.6 49 4.3 4.6 2.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDO71385.1 - 0.67 9.9 11.1 0.4 10.6 1.0 3.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDO71385.1 - 0.93 9.7 5.0 6.1 7.1 0.1 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CDO71385.1 - 1.5 8.6 4.6 16 5.3 0.2 3.1 3 0 0 3 3 3 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 CDO71385.1 - 1.5 8.7 7.5 19 5.2 0.0 3.3 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) tRNA-synt_2c PF01411.19 CDO71386.1 - 2.5e-05 23.0 0.0 3.6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CDO71386.1 - 0.009 16.1 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CDO71386.1 - 9.8 6.6 6.3 89 3.5 6.3 2.3 1 1 0 1 1 1 0 DHHA1 domain MFS_1 PF07690.16 CDO71387.1 - 5.8e-39 134.0 29.8 2.5e-37 128.6 29.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2 PF00703.21 CDO71388.1 - 9.7e-09 35.9 0.0 2.9e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 CDO71388.1 - 2e-05 25.1 0.3 0.12 13.0 0.1 3.0 3 0 0 3 3 3 2 Mannosidase Ig/CBM-like domain Glyco_hydro_2_N PF02837.18 CDO71388.1 - 0.001 19.0 0.1 0.0024 17.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 CDO71388.1 - 0.057 12.5 0.2 0.27 10.3 0.2 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 CDO71388.1 - 0.067 13.0 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 Ig-fold domain Ras PF00071.22 CDO71389.1 - 2.7e-44 150.6 1.1 5e-44 149.8 0.2 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CDO71389.1 - 1.1e-13 51.4 0.0 3.2e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO71389.1 - 1.2e-05 24.8 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDO71389.1 - 0.00014 21.8 0.0 0.0099 15.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CDO71389.1 - 0.00016 21.3 0.5 0.00034 20.2 0.5 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CDO71389.1 - 0.0044 16.6 0.1 0.093 12.3 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CDO71389.1 - 0.011 15.7 0.1 0.031 14.4 0.0 1.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 CDO71389.1 - 0.045 13.7 0.1 0.16 11.9 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1_Xtn PF16897.5 CDO71389.1 - 0.065 13.3 0.1 0.16 12.0 0.0 1.7 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain Spo12 PF05032.12 CDO71390.1 - 7.3e-16 57.8 4.7 7.3e-16 57.8 4.7 1.9 2 0 0 2 2 2 1 Spo12 family Chitin_synth_1 PF01644.17 CDO71391.1 - 2.7e-66 222.6 0.0 4.2e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CDO71391.1 - 9.6e-30 102.4 0.1 3.4e-29 100.6 0.1 2.0 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CDO71391.1 - 2e-25 89.4 1.2 4.6e-20 71.7 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CDO71391.1 - 3.9e-09 36.7 0.1 3.9e-09 36.7 0.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 GST_C PF00043.25 CDO71392.1 - 0.00014 22.0 0.1 0.00022 21.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO71392.1 - 0.00045 20.2 0.2 0.00099 19.1 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Molydop_binding PF01568.21 CDO71392.1 - 0.0091 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain GST_C_3 PF14497.6 CDO71392.1 - 0.0093 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CLPTM1 PF05602.12 CDO71393.1 - 5.5e-138 460.6 0.0 6.6e-138 460.3 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 CDO71393.1 - 0.00046 19.9 0.2 0.0013 18.5 0.2 1.8 1 0 0 1 1 1 1 PQ loop repeat GnsAB_toxin PF08178.11 CDO71394.1 - 0.0061 16.5 0.3 0.013 15.5 0.3 1.4 1 0 0 1 1 1 1 GnsA/GnsB toxin of bacterial toxin-antitoxin system MAS20 PF02064.15 CDO71395.1 - 2.5e-37 127.8 2.0 2.5e-37 127.8 2.0 2.3 3 0 0 3 3 3 1 MAS20 protein import receptor SET PF00856.28 CDO71395.1 - 1.2e-13 51.8 0.0 1.1e-12 48.6 0.0 2.2 2 0 0 2 2 2 1 SET domain PBAN PF05874.11 CDO71395.1 - 0.0037 17.2 1.8 2.6 7.9 0.1 2.9 3 0 0 3 3 3 2 Pheromone biosynthesis activating neuropeptide (PBAN) DUF2256 PF10013.9 CDO71395.1 - 0.018 15.1 0.0 0.053 13.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) CbtB PF09489.10 CDO71395.1 - 0.15 12.2 0.2 0.46 10.6 0.2 1.8 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) zf-MYND PF01753.18 CDO71395.1 - 3.3 7.9 6.5 0.18 11.9 0.4 1.9 2 0 0 2 2 2 0 MYND finger AAA PF00004.29 CDO71396.1 - 1.3e-16 61.2 0.0 2.6e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sporozoite_P67 PF05642.11 CDO71397.1 - 0.089 10.9 4.6 0.11 10.6 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PGPGW PF09656.10 CDO71397.1 - 0.18 11.4 0.4 0.34 10.4 0.4 1.4 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) p450 PF00067.22 CDO71398.1 - 2e-56 191.7 0.2 2.4e-55 188.1 0.2 2.3 1 1 0 1 1 1 1 Cytochrome P450 tRNA-synt_1c PF00749.21 CDO71399.1 - 3.6e-108 361.2 0.0 5e-108 360.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 CDO71399.1 - 2.5e-40 138.1 0.0 4.1e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 CDO71399.1 - 1.4e-29 103.2 0.0 3.8e-29 101.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 CDO71399.1 - 3.8e-05 24.5 0.8 3.8e-05 24.5 0.8 2.5 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 p450 PF00067.22 CDO71400.1 - 5e-48 164.0 0.0 1.1e-35 123.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 TPR_14 PF13428.6 CDO71400.1 - 0.18 12.7 1.0 0.58 11.1 1.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Bin3 PF06859.12 CDO71401.1 - 5.7e-34 117.0 0.0 7.3e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 CDO71401.1 - 9.2e-06 26.3 0.0 1.6e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO71401.1 - 1.3e-05 25.7 0.0 2.8e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO71401.1 - 1.9e-05 24.5 0.0 2.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO71401.1 - 2e-05 24.5 0.0 2.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO71401.1 - 2.8e-05 24.8 0.0 4.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CDO71401.1 - 0.056 12.7 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HAD_2 PF13419.6 CDO71402.1 - 1.7e-14 54.3 0.0 3.6e-12 46.7 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDO71402.1 - 1.6e-08 35.1 0.0 2.4e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDO71402.1 - 1.8e-08 34.3 0.0 5.4e-08 32.8 0.0 1.8 1 1 1 2 2 2 1 HAD-hyrolase-like Sec15 PF04091.12 CDO71403.1 - 3.9e-92 309.0 0.1 8e-92 308.0 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 CDO71403.1 - 3.1e-07 30.4 3.1 3.5e-07 30.2 0.2 2.7 3 1 0 3 3 3 1 Vps51/Vps67 COG5 PF10392.9 CDO71403.1 - 2e-06 28.0 0.4 2e-06 28.0 0.4 3.3 3 1 1 4 4 4 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 CDO71403.1 - 3.1e-05 23.9 0.3 3.1e-05 23.9 0.3 3.2 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 CDO71403.1 - 0.0029 17.7 3.9 0.013 15.6 0.7 3.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.13 CDO71403.1 - 0.0098 14.5 1.7 0.038 12.6 0.3 2.1 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Dor1 PF04124.12 CDO71403.1 - 0.078 11.6 3.4 0.81 8.3 0.1 2.6 2 0 0 2 2 2 0 Dor1-like family RAC_head PF16717.5 CDO71403.1 - 0.76 10.8 5.0 4.9 8.2 0.2 3.5 3 1 1 4 4 4 0 Ribosome-associated complex head domain FAP206 PF12018.8 CDO71403.1 - 1.2 8.6 4.1 1.1 8.7 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function Arf PF00025.21 CDO71404.1 - 1.3e-79 265.7 0.1 1.5e-79 265.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CDO71404.1 - 1.9e-14 53.9 0.0 2.6e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CDO71404.1 - 4.2e-14 52.4 0.0 5.2e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDO71404.1 - 4e-13 49.2 1.3 2.7e-09 36.7 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CDO71404.1 - 1.1e-12 47.9 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDO71404.1 - 1.4e-10 41.0 0.0 1.7e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDO71404.1 - 1.9e-06 27.9 0.0 2.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CDO71404.1 - 0.0068 15.7 0.7 0.02 14.2 0.7 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase CPSF100_C PF13299.6 CDO71405.1 - 5.2e-22 78.8 8.2 3e-19 69.9 0.0 4.1 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 CDO71405.1 - 4.9e-12 46.1 0.0 6.4e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 CDO71405.1 - 1.7e-06 27.9 0.0 4.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CAP_N PF01213.19 CDO71407.1 - 1.4 8.3 4.8 1.5 8.2 3.3 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ILVD_EDD PF00920.21 CDO71408.1 - 2.9e-209 696.0 0.0 3.3e-209 695.8 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Septin PF00735.18 CDO71409.1 - 3.1e-30 105.4 0.0 1.9e-09 37.2 0.0 3.1 3 0 0 3 3 3 3 Septin Zn_clus PF00172.18 CDO71409.1 - 2.3e-12 46.8 28.4 3.5e-08 33.4 11.4 2.9 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Septin PF00735.18 CDO71410.1 - 4.7e-50 170.4 0.2 2.7e-19 69.5 0.0 4.0 4 0 0 4 4 4 3 Septin GTP_EFTU PF00009.27 CDO71410.1 - 7.4e-07 28.9 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDO71410.1 - 8.4e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDO71410.1 - 0.0014 19.1 0.0 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDO71410.1 - 0.0085 16.4 0.1 0.03 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CDO71410.1 - 0.073 13.1 0.1 13 5.8 0.0 2.5 1 1 1 2 2 2 0 Dynamin family AAA_28 PF13521.6 CDO71410.1 - 0.076 13.3 0.2 0.22 11.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 CDO71410.1 - 0.1 12.0 0.1 0.29 10.6 0.1 1.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.18 CDO71410.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.6 CDO71410.1 - 0.19 12.3 1.8 0.21 12.1 0.1 2.0 2 1 0 2 2 2 0 AAA domain CM_2 PF01817.21 CDO71411.1 - 1.2e-06 28.7 0.1 0.0024 18.2 0.0 2.5 2 0 0 2 2 2 2 Chorismate mutase type II RPAP1_N PF08621.10 CDO71411.1 - 0.069 12.9 1.3 8.5 6.2 0.0 3.0 3 0 0 3 3 3 0 RPAP1-like, N-terminal Thi4 PF01946.17 CDO71412.1 - 6.1e-16 58.4 0.2 1.2e-15 57.4 0.2 1.4 1 1 0 1 1 1 1 Thi4 family NDK PF00334.19 CDO71413.1 - 8.6e-16 58.2 0.0 2.5e-15 56.7 0.0 1.7 1 1 0 1 1 1 1 Nucleoside diphosphate kinase Tam41_Mmp37 PF09139.11 CDO71414.1 - 6.3e-113 377.5 0.0 7.6e-113 377.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial CAP_N PF01213.19 CDO71414.1 - 8.6 5.7 8.3 14 5.1 8.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aldo_ket_red PF00248.21 CDO71415.1 - 1.2e-18 67.4 0.3 4.1e-10 39.4 0.1 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Eaf7 PF07904.13 CDO71416.1 - 1.2e-16 61.0 0.0 1.9e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Alg6_Alg8 PF03155.15 CDO71417.1 - 7e-113 378.2 13.8 8.2e-103 344.9 6.2 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Ribosomal_L22 PF00237.19 CDO71417.1 - 5.6e-35 119.7 0.2 8.8e-35 119.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RE_Eco29kI PF09517.10 CDO71417.1 - 0.026 14.2 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Eco29kI restriction endonuclease Nas2_N PF18265.1 CDO71418.1 - 1.9e-29 101.4 0.3 2.7e-29 100.9 0.3 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain GRASP55_65 PF04495.14 CDO71418.1 - 1.6e-09 38.2 0.0 2.4e-09 37.6 0.0 1.3 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 CDO71418.1 - 2.6e-06 27.2 1.0 1.9e-05 24.4 1.0 2.1 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CDO71418.1 - 1.9e-05 24.9 0.0 4.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Hjc PF01870.18 CDO71418.1 - 0.039 13.9 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) AidB_N PF18158.1 CDO71419.1 - 9.1e-26 90.7 0.0 1.4e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 CDO71419.1 - 2e-16 60.5 0.2 3.9e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDO71419.1 - 7.2e-10 38.9 0.0 1.6e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CDO71419.1 - 0.0031 17.8 0.0 0.0078 16.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CDO71419.1 - 0.14 12.9 0.0 0.35 11.6 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain PhoLip_ATPase_C PF16212.5 CDO71420.1 - 0.00082 19.2 4.2 0.00082 19.2 4.2 1.6 1 1 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase_C PF00689.21 CDO71420.1 - 0.027 14.2 8.8 0.076 12.7 8.7 1.9 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus SdpI PF13630.6 CDO71420.1 - 0.035 14.2 0.7 0.035 14.2 0.7 3.2 3 1 0 3 3 3 0 SdpI/YhfL protein family DUF4079 PF13301.6 CDO71420.1 - 0.044 13.9 0.7 0.13 12.4 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) 4HBT PF03061.22 CDO71421.1 - 2.6e-14 53.3 0.3 3.5e-14 52.9 0.3 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DER1 PF04511.15 CDO71422.1 - 2.8e-47 161.1 4.9 5.8e-47 160.1 4.9 1.5 1 0 0 1 1 1 1 Der1-like family Jiraiya PF15038.6 CDO71422.1 - 0.035 13.5 1.1 0.092 12.2 0.1 2.1 2 0 0 2 2 2 0 Jiraiya SET PF00856.28 CDO71423.1 - 1e-07 32.5 0.0 1.6e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 SET domain Pro_isomerase PF00160.21 CDO71424.1 - 7.1e-51 172.6 0.0 1.4e-50 171.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CDO71424.1 - 1.3e-07 32.2 0.0 0.053 14.4 0.0 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO71424.1 - 0.061 13.6 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-AN1 PF01428.16 CDO71425.1 - 7.5e-20 70.8 29.7 1.2e-10 41.3 7.6 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CDO71425.1 - 3.4e-05 24.1 16.0 0.0022 18.3 1.9 2.3 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain His_Phos_1 PF00300.22 CDO71426.1 - 9.8e-24 84.1 0.0 1.7e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ufd2P_core PF10408.9 CDO71427.1 - 3.7e-223 742.7 1.6 4.5e-223 742.4 1.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CDO71427.1 - 3.9e-30 103.8 0.5 2.3e-29 101.4 0.6 2.4 2 0 0 2 2 2 1 U-box domain Mon1 PF03164.14 CDO71428.1 - 3.8e-49 167.8 0.0 4.2e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 BTB PF00651.31 CDO71429.1 - 3e-05 24.2 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CelTOS PF18659.1 CDO71429.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites Amidohydro_1 PF01979.20 CDO71430.1 - 1.8e-24 86.7 0.0 7.7e-23 81.3 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDO71430.1 - 5.2e-08 32.8 0.1 6.6e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family tRNA_int_endo_N PF02778.14 CDO71430.1 - 0.074 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain A_deaminase PF00962.22 CDO71430.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Adenosine/AMP deaminase EBP PF05241.12 CDO71431.1 - 3.3e-68 228.6 10.1 3.9e-68 228.4 10.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein ORC6 PF05460.13 CDO71432.1 - 0.003 16.9 0.0 0.003 16.9 0.0 4.0 2 1 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) YjeF_N PF03853.15 CDO71433.1 - 1.6e-18 67.2 0.0 1.8e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus zf-MYND PF01753.18 CDO71434.1 - 9.9e-11 41.6 5.3 4.5e-10 39.5 5.3 2.3 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 CDO71434.1 - 0.0032 17.5 1.2 0.0032 17.5 1.2 2.1 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 vATP-synt_AC39 PF01992.16 CDO71435.1 - 1.8e-51 175.7 0.0 2e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CRAL_TRIO PF00650.20 CDO71436.1 - 4e-28 98.1 0.0 6.2e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDO71436.1 - 2.9e-06 27.4 0.1 7.2e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Herpes_BLLF1 PF05109.13 CDO71436.1 - 0.72 7.8 8.7 0.97 7.3 8.7 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Glyco_hydro_71 PF03659.14 CDO71437.1 - 5e-110 367.8 0.4 5.8e-110 367.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_71 PF03659.14 CDO71438.1 - 1.9e-114 382.4 4.1 2.4e-114 382.1 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Ribosomal_L6 PF00347.23 CDO71439.1 - 3.1e-24 85.4 0.0 1.6e-13 51.1 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 tRNA_bind PF01588.20 CDO71440.1 - 5.1e-29 100.2 0.0 9.5e-29 99.4 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 CDO71440.1 - 8.1e-05 22.8 0.0 8.1e-05 22.8 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO71440.1 - 0.00032 20.8 0.0 0.00032 20.8 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO71440.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Presenilin PF01080.17 CDO71440.1 - 0.1 11.3 4.9 0.13 11.0 4.9 1.1 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 CDO71440.1 - 0.12 12.3 13.1 0.19 11.7 13.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Zip PF02535.22 CDO71440.1 - 0.57 9.3 2.7 0.67 9.1 2.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 CDO71440.1 - 1.4 7.6 3.9 1.7 7.3 3.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.6 CDO71440.1 - 1.7 8.5 18.4 2.9 7.8 18.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO NARP1 PF12569.8 CDO71440.1 - 1.8 7.4 19.2 2.7 6.8 19.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DIOX_N PF14226.6 CDO71441.1 - 1.2e-25 90.5 0.0 1.8e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO71441.1 - 2.5e-08 34.3 0.0 7.8e-08 32.7 0.0 1.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CBFD_NFYB_HMF PF00808.23 CDO71442.1 - 6.1e-08 32.8 0.0 8.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1849 PF08904.11 CDO71442.1 - 0.04 13.5 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) Pes-10 PF07149.11 CDO71442.1 - 0.16 11.0 2.1 0.24 10.4 2.1 1.2 1 0 0 1 1 1 0 Pes-10 HSP20 PF00011.21 CDO71443.1 - 8.6e-16 57.9 0.2 1.2e-09 38.3 0.0 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDO71443.1 - 2.3e-12 46.2 0.0 3.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 CDO71443.1 - 0.0014 18.7 1.9 0.014 15.4 0.0 2.0 1 1 0 2 2 2 1 GvpH FKBP26_C PF18046.1 CDO71443.1 - 0.0092 16.1 0.2 6.1 7.0 0.1 2.2 2 0 0 2 2 2 2 FKBP26_C-terminal PilZ PF07238.14 CDO71443.1 - 0.017 15.4 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 PilZ domain DUF1325 PF07039.11 CDO71444.1 - 4.3e-33 114.2 0.0 6.3e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain SEN1_N PF12726.7 CDO71445.1 - 3.5e-150 501.7 5.2 5.7e-150 501.0 5.2 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 CDO71445.1 - 1.2e-71 241.6 1.0 5.7e-71 239.4 0.8 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 CDO71445.1 - 1.1e-60 204.7 0.0 3.2e-60 203.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDO71445.1 - 2.5e-10 40.4 0.0 3.2e-06 27.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDO71445.1 - 3e-09 37.4 0.7 2.3e-08 34.5 0.7 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDO71445.1 - 2.1e-05 24.4 0.2 0.011 15.5 0.1 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF3552 PF12072.8 CDO71445.1 - 0.00073 19.0 7.8 0.0021 17.5 7.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ResIII PF04851.15 CDO71445.1 - 0.033 14.2 0.0 0.18 11.8 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CDO71445.1 - 0.18 12.1 1.3 1.2 9.4 0.5 2.8 1 1 1 2 2 2 0 AAA domain Glyco_hydro_71 PF03659.14 CDO71446.1 - 4e-122 407.7 4.7 4.6e-122 407.5 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 HMG-CoA_red PF00368.18 CDO71446.1 - 0.0025 16.9 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase CS PF04969.16 CDO71447.1 - 7.1e-11 43.0 0.0 1.7e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 CS domain SAD_SRA PF02182.17 CDO71448.1 - 7.4e-42 142.7 0.2 1.6e-41 141.6 0.1 1.6 2 0 0 2 2 2 1 SAD/SRA domain PP2C PF00481.21 CDO71449.1 - 8.7e-71 238.6 0.0 1.4e-70 237.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C BUD22 PF09073.10 CDO71449.1 - 0.021 14.2 3.0 0.033 13.5 1.6 1.8 2 0 0 2 2 2 0 BUD22 TetR_C_7 PF14246.6 CDO71449.1 - 0.083 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain DNA_pol_phi PF04931.13 CDO71449.1 - 0.97 7.5 6.8 1.3 7.0 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Scm3 PF10384.9 CDO71451.1 - 6.1e-06 25.9 0.1 3.5e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Centromere protein Scm3 DUF2967 PF11179.8 CDO71451.1 - 0.0028 15.8 0.2 0.0036 15.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2967) BUD22 PF09073.10 CDO71453.1 - 6.5e-41 141.1 29.4 3.5e-30 105.7 18.7 2.1 1 1 1 2 2 2 2 BUD22 ESM4 PF15952.5 CDO71453.1 - 0.13 12.6 0.6 0.29 11.6 0.5 1.4 1 1 0 1 1 1 0 Enhancer of split M4 family F-box-like PF12937.7 CDO71455.1 - 8.4e-09 35.2 0.0 2.1e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 F-box-like Pes-10 PF07149.11 CDO71455.1 - 0.14 11.2 0.7 0.21 10.6 0.7 1.3 1 0 0 1 1 1 0 Pes-10 DUF2892 PF11127.8 CDO71456.1 - 0.26 11.3 2.2 0.62 10.1 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) APH PF01636.23 CDO71457.1 - 4e-13 49.8 0.2 9.6e-13 48.6 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO71457.1 - 2.6e-08 33.7 0.0 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 CDO71457.1 - 0.11 11.8 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 CDO71457.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO71458.1 - 0.0021 18.0 0.1 0.011 15.7 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO71458.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATP-synt_ab PF00006.25 CDO71459.1 - 2.3e-54 184.3 0.0 6e-52 176.4 0.0 2.2 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CDO71459.1 - 6.1e-13 49.1 0.9 1.2e-12 48.2 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain TFCD_C PF12612.8 CDO71460.1 - 1.7e-40 138.9 0.1 1e-39 136.4 0.0 2.4 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 CDO71460.1 - 0.24 11.8 11.2 2.7 8.5 1.1 5.1 3 2 2 5 5 5 0 HEAT repeats PH_4 PF15404.6 CDO71462.1 - 1.2e-20 74.1 2.1 1.9e-11 44.1 0.0 3.5 3 1 1 4 4 4 2 Pleckstrin homology domain PH_6 PF15406.6 CDO71462.1 - 0.15 12.3 0.2 3.3 8.0 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain DUF755 PF05501.11 CDO71462.1 - 9.9 6.5 8.2 24 5.2 8.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosom_S12_S23 PF00164.25 CDO71463.1 - 1e-28 99.3 0.1 1.4e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 zf-Nse PF11789.8 CDO71464.1 - 1.1e-15 57.2 0.0 1.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CDO71464.1 - 0.0016 18.5 0.1 0.003 17.6 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDO71464.1 - 0.0053 16.6 0.0 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 CDO71464.1 - 0.0065 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain CNDH2_M PF16869.5 CDO71464.1 - 0.8 10.4 13.4 7.2 7.3 7.0 2.6 2 0 0 2 2 2 0 PF16858 DDE_1 PF03184.19 CDO71465.1 - 3.6e-37 127.7 0.0 6.7e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CDO71465.1 - 7.1e-10 38.8 0.1 1.9e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF4817 PF16087.5 CDO71465.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) MRP-L47 PF06984.13 CDO71466.1 - 5e-20 71.4 1.0 1.1e-19 70.3 1.0 1.6 1 1 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 CDO71466.1 - 0.014 15.4 2.9 0.056 13.4 2.9 2.1 1 1 0 1 1 1 0 Ribosomal L29 protein SQS_PSY PF00494.19 CDO71467.1 - 1.3e-45 156.0 0.0 1.6e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase DAZAP2 PF11029.8 CDO71468.1 - 0.012 16.5 1.4 0.029 15.3 0.0 2.2 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) baeRF_family5 PF18846.1 CDO71468.1 - 0.17 12.1 3.9 1.1 9.5 0.2 2.4 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 Amidohydro_1 PF01979.20 CDO71469.1 - 0.018 14.4 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family DIOX_N PF14226.6 CDO71470.1 - 2.6e-25 89.4 0.0 4e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO71470.1 - 9.5e-17 61.4 0.0 1.8e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CDO71471.1 - 8.7e-25 87.8 0.0 1.3e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO71471.1 - 1.4e-19 70.5 0.0 2.1e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.7 CDO71472.1 - 7.6e-10 39.8 0.1 9.7e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AOX PF01786.17 CDO71473.1 - 5.3e-96 320.3 0.4 6.5e-96 320.0 0.4 1.1 1 0 0 1 1 1 1 Alternative oxidase Peptidase_S66C PF17676.1 CDO71473.1 - 0.12 12.9 0.1 0.62 10.6 0.0 2.1 2 0 0 2 2 2 0 LD-carboxypeptidase C-terminal domain Fungal_trans PF04082.18 CDO71474.1 - 2.2e-09 36.7 0.1 3.9e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CDO71474.1 - 0.018 15.2 16.0 0.034 14.3 16.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Putative_PNPOx PF01243.20 CDO71475.1 - 4.4e-23 81.3 0.2 7.2e-23 80.6 0.2 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 CDO71475.1 - 3.3e-13 49.5 0.4 7.6e-13 48.3 0.4 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 CDO71475.1 - 3.6e-05 24.3 0.1 6.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 CDO71475.1 - 0.042 13.4 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Kelch_6 PF13964.6 CDO71476.1 - 1e-16 60.5 3.0 0.0019 18.4 0.0 5.5 5 1 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 CDO71476.1 - 2.2e-15 56.2 1.4 0.00082 19.3 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CDO71476.1 - 8.9e-15 54.0 0.2 0.00013 21.4 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 CDO71476.1 - 2e-14 52.9 0.1 0.0073 16.2 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 CDO71476.1 - 3e-13 49.7 4.0 3.3e-07 30.4 0.0 6.9 7 0 0 7 7 7 1 Galactose oxidase, central domain Kelch_4 PF13418.6 CDO71476.1 - 2.4e-12 46.7 3.9 0.0026 17.7 0.1 4.9 4 1 0 4 4 4 3 Galactose oxidase, central domain SRP-alpha_N PF04086.13 CDO71476.1 - 6.3 6.6 11.1 11 5.9 11.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-CCHH PF10283.9 CDO71477.1 - 0.00047 20.1 1.2 0.00078 19.4 1.2 1.4 1 0 0 1 1 1 1 PBZ domain zf-CRD PF17979.1 CDO71477.1 - 0.027 14.6 0.0 0.091 12.9 0.0 1.9 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Lustrin_cystein PF14625.6 CDO71477.1 - 0.38 11.1 5.3 6 7.3 1.4 2.3 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Lipase_3 PF01764.25 CDO71479.1 - 5.2e-24 84.7 0.0 7.7e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) FHA PF00498.26 CDO71479.1 - 8e-07 29.3 0.0 1.8e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Abhydrolase_6 PF12697.7 CDO71479.1 - 0.0082 16.8 0.1 0.0082 16.8 0.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CDO71479.1 - 0.0095 15.7 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 CDO71479.1 - 0.056 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 CDO71479.1 - 0.098 12.6 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) zf-C2H2 PF00096.26 CDO71480.1 - 0.00056 20.2 5.6 0.36 11.4 2.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO71480.1 - 0.0017 19.0 4.4 1.9 9.5 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDO71480.1 - 0.023 15.1 2.9 0.58 10.7 0.5 2.9 2 0 0 2 2 2 0 Zinc-finger double domain PBP1_TM PF14812.6 CDO71480.1 - 8.7 6.8 6.3 3.3 8.1 0.9 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 CDO71481.1 - 1.7e-68 230.8 0.0 2.3e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71481.1 - 1.3e-35 123.0 0.0 6.5e-35 120.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO71481.1 - 0.00054 19.4 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDO71481.1 - 0.005 15.7 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CDO71481.1 - 0.081 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CDO71481.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M3 PF01432.20 CDO71482.1 - 4.7e-133 444.8 0.0 6.5e-133 444.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CDO71482.1 - 0.061 13.0 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like RIO1 PF01163.22 CDO71483.1 - 5.7e-37 127.1 4.5 4.9e-23 81.7 0.0 2.8 3 0 0 3 3 3 2 RIO1 family MFMR_assoc PF16596.5 CDO71483.1 - 5.5 7.4 11.8 2.4 8.6 8.1 2.3 2 0 0 2 2 2 0 Disordered region downstream of MFMR Peptidase_M3 PF01432.20 CDO71484.1 - 3.3e-105 353.0 0.5 5.9e-63 213.7 0.2 2.1 1 1 1 2 2 2 2 Peptidase family M3 UDPGT PF00201.18 CDO71485.1 - 2.1e-16 59.8 0.1 5e-16 58.6 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO71485.1 - 0.00013 22.0 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain HU-CCDC81_bac_2 PF18175.1 CDO71485.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Usp PF00582.26 CDO71486.1 - 3.9e-05 24.2 0.1 0.00013 22.5 0.1 1.9 1 0 0 1 1 1 1 Universal stress protein family Pet127 PF08634.10 CDO71487.1 - 2.9e-97 325.4 0.4 3.9e-97 324.9 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Proteasom_Rpn13 PF04683.13 CDO71488.1 - 1.4e-29 102.5 0.0 1.9e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 CDO71488.1 - 3.3e-28 98.1 0.0 4.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 UCH-binding domain Frankia_peptide PF14407.6 CDO71488.1 - 0.035 14.1 0.0 0.42 10.6 0.0 2.5 3 0 0 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. L27_2 PF09045.10 CDO71489.1 - 0.3 11.1 0.2 0.3 11.1 0.2 2.0 2 0 0 2 2 2 0 L27_2 LRR_4 PF12799.7 CDO71489.1 - 1.5 9.3 6.3 6.3 7.4 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF2205 PF10224.9 CDO71490.1 - 2.6e-09 36.9 0.8 3.1e-09 36.7 0.8 1.1 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 CDO71490.1 - 0.0036 17.9 1.1 0.0039 17.8 1.1 1.1 1 0 0 1 1 1 1 Initiation control protein YabA Endotoxin_C2 PF18449.1 CDO71490.1 - 0.077 13.3 2.4 0.91 9.9 0.2 2.2 2 0 0 2 2 2 0 Delta endotoxin AAA_23 PF13476.6 CDO71491.1 - 3.8e-32 112.4 0.0 3.8e-32 112.4 0.0 8.9 1 1 5 6 6 3 1 AAA domain SMC_N PF02463.19 CDO71491.1 - 1.1e-16 61.0 14.6 7.6e-09 35.3 0.0 3.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDO71491.1 - 9.2e-14 51.9 2.3 3.5e-06 27.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDO71491.1 - 1.1e-09 38.6 2.2 1.1e-09 38.6 2.2 5.4 2 1 2 4 4 3 1 AAA ATPase domain SbcCD_C PF13558.6 CDO71491.1 - 2.2e-06 27.8 0.0 8.8e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CDO71491.1 - 0.0014 18.3 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Roc PF08477.13 CDO71491.1 - 0.0019 18.4 0.5 0.0067 16.6 0.0 2.2 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 CDO71491.1 - 0.0037 16.0 0.0 0.0037 16.0 0.0 8.2 3 1 5 8 8 7 3 AAA domain ABC_tran PF00005.27 CDO71491.1 - 0.0069 16.9 0.0 0.0069 16.9 0.0 7.3 5 2 2 7 7 5 2 ABC transporter Rad50_zn_hook PF04423.14 CDO71491.1 - 0.01 15.6 0.3 0.01 15.6 0.3 5.1 4 0 0 4 4 4 0 Rad50 zinc hook motif AAA_16 PF13191.6 CDO71491.1 - 0.21 12.0 0.0 0.21 12.0 0.0 5.6 3 2 1 4 4 1 0 AAA ATPase domain GTP_EFTU PF00009.27 CDO71491.1 - 0.35 10.4 0.0 0.35 10.4 0.0 3.7 3 1 0 3 3 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CDO71491.1 - 1.1 9.5 4.6 1.2 9.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain AMP-binding PF00501.28 CDO71492.1 - 2.2e-78 263.7 0.3 3.2e-78 263.2 0.3 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Cytochrom_B561 PF03188.16 CDO71492.1 - 0.0039 17.3 4.0 0.01 16.0 4.0 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4396 PF14342.6 CDO71492.1 - 0.0047 17.3 1.1 0.015 15.6 1.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Pkinase PF00069.25 CDO71494.1 - 5.2e-55 186.6 0.0 7.5e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71494.1 - 4.3e-25 88.5 0.2 4.6e-23 81.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDO71494.1 - 0.00015 21.2 0.7 0.0059 16.0 0.0 2.7 2 1 1 3 3 3 1 Kinase-like RIO1 PF01163.22 CDO71494.1 - 0.0017 17.9 0.1 0.0054 16.3 0.1 1.8 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CDO71494.1 - 0.0026 17.2 0.4 0.0044 16.4 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CDO71494.1 - 0.0052 16.4 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CDO71494.1 - 0.19 10.5 0.1 0.33 9.7 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase cobW PF02492.19 CDO71495.1 - 9.9e-21 74.1 0.0 1.4e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 CDO71495.1 - 0.002 18.2 0.0 0.004 17.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase TIP49 PF06068.13 CDO71495.1 - 0.024 13.8 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 CDO71495.1 - 0.039 14.4 0.0 0.057 13.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.23 CDO71495.1 - 0.054 13.6 0.1 0.08 13.0 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 CDO71495.1 - 0.071 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 CDO71495.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CDO71495.1 - 0.09 13.3 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDO71495.1 - 0.093 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 CDO71495.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Roc PF08477.13 CDO71495.1 - 0.11 12.7 0.0 0.9 9.8 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CDO71495.1 - 0.19 12.1 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.12 CDO71495.1 - 0.24 10.8 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Abhydrolase_1 PF00561.20 CDO71496.1 - 9.8e-22 77.8 0.0 5.6e-20 72.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO71496.1 - 1e-13 52.4 0.1 1.3e-13 52.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO71496.1 - 0.0019 17.5 0.0 0.018 14.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 CDO71496.1 - 0.14 11.0 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme HA2 PF04408.23 CDO71497.1 - 4.9e-22 78.3 0.0 4.9e-22 78.3 0.0 4.4 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDO71497.1 - 3.1e-20 72.3 0.4 7.2e-20 71.1 0.4 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDO71497.1 - 1.2e-15 57.8 0.0 4.1e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDO71497.1 - 1.7e-07 31.2 0.1 2.7e-06 27.3 0.0 2.8 2 1 1 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CDO71497.1 - 7.8e-05 22.5 1.0 0.00018 21.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDO71497.1 - 8.9e-05 22.8 0.1 0.00057 20.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDO71497.1 - 0.0015 18.9 0.6 0.0053 17.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CDO71497.1 - 0.013 14.6 0.0 0.034 13.2 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 CDO71497.1 - 0.074 13.0 0.0 4 7.4 0.0 3.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Questin_oxidase PF14027.6 CDO71498.1 - 1.4e-74 251.7 0.0 4.6e-72 243.4 0.0 2.0 1 1 0 1 1 1 1 Questin oxidase-like Pkinase_fungal PF17667.1 CDO71499.1 - 4.5e-48 164.0 0.0 1.9e-47 162.0 0.0 1.9 1 1 0 1 1 1 1 Fungal protein kinase Plavaka PF18759.1 CDO71501.1 - 3.3e-125 417.6 0.0 4.4e-125 417.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase TSC22 PF01166.18 CDO71502.1 - 0.023 15.0 0.2 3 8.2 0.2 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF1664 PF07889.12 CDO71502.1 - 0.027 14.5 0.1 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 CDO71503.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 CDO71504.1 - 0.051 12.9 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 CDO71505.1 - 0.00021 20.8 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDO71505.1 - 0.00085 18.2 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDO71505.1 - 0.0014 18.0 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO71505.1 - 0.0041 17.1 0.5 0.15 11.9 0.3 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family UvrD_C PF13361.6 CDO71505.1 - 0.024 14.0 0.1 0.035 13.5 0.1 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain EcKinase PF02958.20 CDO71505.1 - 0.053 12.8 0.0 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 Ecdysteroid kinase Pam16 PF03656.13 CDO71505.1 - 0.15 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Pam16 RIO1 PF01163.22 CDO71505.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Peptidase_M20 PF01546.28 CDO71506.1 - 5.9e-35 120.9 0.0 8.2e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDO71506.1 - 7.9e-12 45.1 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CDO71506.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 p450 PF00067.22 CDO71507.1 - 4.6e-66 223.5 0.0 8.4e-66 222.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 UDPG_MGDP_dh_N PF03721.14 CDO71509.1 - 5.1e-50 169.7 0.0 8.6e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 CDO71509.1 - 4.6e-31 106.9 0.0 8.3e-31 106.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 CDO71509.1 - 4.2e-27 94.6 0.2 7.6e-26 90.6 0.1 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.17 CDO71509.1 - 0.091 13.4 0.3 1.7 9.3 0.1 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UCH PF00443.29 CDO71510.1 - 2.1e-08 34.0 0.4 7.9e-08 32.1 0.9 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CUE PF02845.16 CDO71510.1 - 0.02 14.6 0.0 0.17 11.6 0.0 2.6 2 0 0 2 2 2 0 CUE domain UCH_1 PF13423.6 CDO71510.1 - 0.063 12.9 0.1 0.61 9.6 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 CDO71510.1 - 0.17 11.9 10.9 0.42 10.7 1.4 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Syntaxin-6_N PF09177.11 CDO71510.1 - 0.5 10.9 3.6 0.4 11.3 0.9 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Aminotran_1_2 PF00155.21 CDO71511.1 - 1.2e-55 189.1 0.0 5.8e-45 154.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.20 CDO71511.1 - 0.00013 20.9 0.0 0.00023 20.0 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 CDO71511.1 - 0.013 14.4 0.0 0.027 13.4 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Dus PF01207.17 CDO71512.1 - 6.6e-47 160.1 0.0 1.1e-46 159.4 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 CDO71512.1 - 1.2e-06 28.3 4.0 0.0028 17.5 0.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CDO71512.1 - 0.00012 21.8 9.0 0.03 14.1 2.3 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CDO71512.1 - 0.0023 18.6 2.2 0.16 12.7 0.6 2.4 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 CDO71512.1 - 0.44 10.7 8.7 1.6 8.9 1.4 2.5 2 0 0 2 2 2 0 Zinc finger domain p450 PF00067.22 CDO71513.1 - 3.8e-66 223.7 0.0 1.1e-65 222.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.23 CDO71514.1 - 8.7e-47 160.1 5.3 1.8e-46 159.0 5.3 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO71514.1 - 1.9e-06 28.3 7.2 0.0054 17.0 0.3 3.4 2 1 2 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO71514.1 - 0.0029 18.2 5.6 0.31 11.7 2.4 2.8 2 0 0 2 2 2 2 Aspartyl protease Ribosomal_L35p PF01632.19 CDO71514.1 - 0.021 15.3 0.1 0.042 14.4 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L35 gag-asp_proteas PF13975.6 CDO71514.1 - 0.1 13.2 2.8 5.6 7.6 0.3 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease C2 PF00168.30 CDO71515.1 - 8.5e-26 90.2 0.0 7.3e-13 48.7 0.0 3.1 3 0 0 3 3 3 2 C2 domain Plasmodium_Vir PF05795.11 CDO71515.1 - 0.14 11.5 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein RNA_pol_Rpc34 PF05158.12 CDO71516.1 - 2.7e-75 253.8 3.1 2.7e-53 181.5 0.3 3.6 1 1 2 3 3 3 3 RNA polymerase Rpc34 subunit EST1 PF10374.9 CDO71517.1 - 2.3e-18 67.1 0.1 5.4e-18 65.9 0.0 1.6 2 0 0 2 2 2 1 Telomerase activating protein Est1 Activator_LAG-3 PF11498.8 CDO71517.1 - 0.25 10.3 7.9 0.36 9.7 7.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EST1_DNA_bind PF10373.9 CDO71518.1 - 4.9e-29 101.7 0.0 1.4e-23 83.8 0.0 2.1 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain SNF2_N PF00176.23 CDO71519.1 - 3.4e-70 236.5 0.1 1.6e-69 234.3 0.0 1.9 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDO71519.1 - 8.7e-21 74.3 0.1 2.5e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO71519.1 - 2.3e-06 27.7 0.0 9.8e-06 25.7 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDO71519.1 - 0.0012 18.7 0.0 0.059 13.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Chorion_2 PF03964.15 CDO71519.1 - 0.0088 16.9 0.1 0.02 15.7 0.1 1.6 1 0 0 1 1 1 1 Chorion family 2 DTHCT PF08070.11 CDO71519.1 - 0.16 12.7 5.1 0.081 13.7 1.4 2.3 2 0 0 2 2 2 0 DTHCT (NUC029) region Fungal_trans PF04082.18 CDO71521.1 - 2.4e-14 53.0 0.0 3.8e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transposase_21 PF02992.14 CDO71523.1 - 1.6e-10 40.6 0.2 9.4e-10 38.1 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 zf-RING_2 PF13639.6 CDO71527.1 - 8.7e-07 29.2 6.2 4.9e-05 23.6 0.7 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 CDO71527.1 - 8e-06 26.0 2.5 3.2e-05 24.1 0.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDO71527.1 - 0.00045 20.0 3.9 0.016 15.1 0.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDO71527.1 - 0.00046 19.9 2.4 0.5 10.2 0.1 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDO71527.1 - 0.0036 17.1 2.0 0.0036 17.1 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDO71527.1 - 0.017 15.0 8.2 0.018 14.9 1.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDO71527.1 - 0.035 14.0 1.5 0.035 14.0 1.5 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CDO71527.1 - 3.1 8.0 8.0 14 6.0 3.3 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain NicO PF03824.16 CDO71528.1 - 0.00015 21.2 0.1 0.0002 20.8 0.1 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF5134 PF17197.4 CDO71528.1 - 0.042 13.8 3.6 0.059 13.3 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) NICE-3 PF07406.11 CDO71528.1 - 0.093 12.7 1.3 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 NICE-3 protein DUF3357 PF11837.8 CDO71528.1 - 0.89 10.0 4.2 0.83 10.1 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Peptidase_S64 PF08192.11 CDO71530.1 - 0.00021 19.9 0.1 0.00034 19.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family S64 AIP3 PF03915.13 CDO71530.1 - 0.055 12.6 0.3 0.084 12.0 0.3 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Fez1 PF06818.15 CDO71530.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 Fez1 CENP-B_dimeris PF09026.10 CDO71530.1 - 0.2 12.0 13.0 0.5 10.8 13.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain D123 PF07065.14 CDO71530.1 - 0.39 9.8 0.0 0.39 9.8 0.0 2.6 4 0 0 4 4 4 0 D123 RXT2_N PF08595.11 CDO71530.1 - 0.87 9.6 4.6 1.5 8.8 4.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 CDO71530.1 - 1.3 8.9 7.4 3 7.7 7.4 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 CDO71530.1 - 1.4 8.2 11.2 2.2 7.5 11.2 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 CDO71530.1 - 1.8 8.2 3.9 3.3 7.4 3.9 1.3 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 CDO71530.1 - 6.8 4.8 7.0 11 4.1 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDO71530.1 - 7.9 4.6 5.3 11 4.1 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CDO71530.1 - 8.4 5.7 7.4 13 5.1 7.4 1.1 1 0 0 1 1 1 0 SDA1 INCENP_ARK-bind PF03941.15 CDO71531.1 - 1.8e-20 72.6 1.7 1.8e-20 72.6 1.7 2.6 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Sigma70_r1_2 PF00140.20 CDO71531.1 - 0.092 12.8 1.6 0.22 11.5 1.6 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 V-SNARE_C PF12352.8 CDO71532.1 - 0.0011 19.2 3.3 0.33 11.3 0.3 2.8 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus DUF5320 PF17253.2 CDO71532.1 - 0.064 14.3 0.4 0.81 10.8 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) APG6_N PF17675.1 CDO71532.1 - 9.3 6.8 13.5 1.3 9.6 0.1 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region Mpp10 PF04006.12 CDO71533.1 - 2.4e-115 386.4 69.0 3.3e-114 382.6 69.0 2.0 1 1 0 1 1 1 1 Mpp10 protein Amidase PF01425.21 CDO71533.1 - 4.3e-103 345.7 0.0 1.1e-102 344.4 0.0 1.6 2 0 0 2 2 2 1 Amidase Lyase_8 PF02278.18 CDO71535.1 - 3.1e-68 230.1 3.3 4.8e-68 229.4 3.3 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 CDO71535.1 - 1.4e-21 76.8 0.0 2e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 CDO71535.1 - 1.4e-09 38.2 0.1 3.1e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Lyase_8 PF02278.18 CDO71536.1 - 2.6e-67 227.0 1.7 4.2e-67 226.3 1.7 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 CDO71536.1 - 8.1e-20 71.0 0.1 1.2e-19 70.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 CDO71536.1 - 4.6e-10 39.8 0.1 1.2e-09 38.5 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Ribosomal_S3_C PF00189.20 CDO71537.1 - 3.5e-24 85.1 0.3 1.2e-23 83.5 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CDO71537.1 - 1.2e-11 44.3 0.0 2.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 CDO71537.1 - 0.074 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Thiolase_C PF02803.18 CDO71538.1 - 2.8e-41 140.0 0.1 5.5e-41 139.1 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 CDO71538.1 - 1.6e-21 76.9 0.4 3.9e-18 65.8 0.1 2.5 2 1 1 3 3 3 2 Thiolase, N-terminal domain CBM-like PF14683.6 CDO71539.1 - 8.1e-25 87.6 0.1 1.4e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 CDO71539.1 - 9e-19 67.0 0.2 1.8e-18 66.1 0.2 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 CDO71539.1 - 0.0042 17.3 0.4 0.0042 17.3 0.4 1.9 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain SAD_SRA PF02182.17 CDO71540.1 - 4e-52 176.1 0.0 6.8e-52 175.3 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain zf-CCCH_4 PF18044.1 CDO71541.1 - 0.00068 19.4 4.8 0.00068 19.4 4.8 3.9 4 0 0 4 4 4 1 CCCH-type zinc finger zf-CCCH PF00642.24 CDO71541.1 - 0.011 15.6 3.8 0.011 15.6 3.8 3.9 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CDO71541.1 - 0.011 15.9 5.9 0.021 15.0 0.2 2.7 2 1 0 2 2 2 0 Zinc-finger containing family Torus PF16131.5 CDO71541.1 - 2.4 8.9 10.2 0.22 12.2 0.6 2.9 1 1 1 2 2 2 0 Torus domain UPF0160 PF03690.13 CDO71544.1 - 3.3e-138 460.6 0.0 4.2e-138 460.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SurE PF01975.17 CDO71544.1 - 3.7e-25 88.8 0.0 9e-24 84.3 0.0 2.2 1 1 0 1 1 1 1 Survival protein SurE DUF3494 PF11999.8 CDO71545.1 - 0.1 12.2 0.6 0.16 11.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) Ribosomal_L15e PF00827.17 CDO71546.1 - 1.9e-92 308.3 11.7 2.1e-92 308.1 11.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 RVT_1 PF00078.27 CDO71547.1 - 3e-42 144.6 0.0 5.2e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 CDO71547.1 - 1.7e-05 24.5 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Golgin_A5 PF09787.9 CDO71547.1 - 0.067 12.6 9.0 0.14 11.6 9.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 YwqJ-deaminase PF14431.6 CDO71547.1 - 0.12 12.5 0.6 0.38 11.0 0.6 1.8 1 0 0 1 1 1 0 YwqJ-like deaminase DUF445 PF04286.12 CDO71547.1 - 0.19 11.5 3.9 1.4 8.7 1.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF445) MFS_1 PF07690.16 CDO71549.1 - 4.6e-08 32.4 20.5 3.4e-07 29.5 7.4 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2157 PF09925.9 CDO71549.1 - 1.2 8.9 7.5 11 5.8 0.0 3.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Rad17 PF03215.15 CDO71550.1 - 0.0031 17.5 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CDO71550.1 - 0.0085 16.5 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.22 CDO71550.1 - 0.042 13.4 0.1 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Ras family AAA_22 PF13401.6 CDO71550.1 - 0.063 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDO71550.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 CDO71550.1 - 0.13 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDO71550.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CDO71550.1 - 0.21 11.1 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RasGEF PF00617.19 CDO71551.1 - 1.3e-30 106.9 0.0 2.2e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain DEAD PF00270.29 CDO71552.1 - 3.7e-48 163.6 0.0 3.2e-47 160.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO71552.1 - 9.4e-31 106.4 0.1 7.6e-29 100.3 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 CDO71552.1 - 0.066 12.0 0.2 1 8.1 0.1 2.6 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ANAPC4 PF12896.7 CDO71553.1 - 1.4e-43 148.8 0.1 2.5e-43 148.0 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 CDO71553.1 - 0.00059 20.1 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain BTAD PF03704.17 CDO71553.1 - 0.26 11.7 3.5 2.7 8.4 0.5 2.6 2 1 0 2 2 2 0 Bacterial transcriptional activator domain CHAD PF05235.14 CDO71553.1 - 1.8 8.5 4.8 0.65 9.9 1.2 1.9 2 0 0 2 2 2 0 CHAD domain Actin PF00022.19 CDO71556.1 - 1.9e-130 435.2 0.0 9.4e-130 432.9 0.0 1.8 1 1 0 1 1 1 1 Actin Ribosomal_S24e PF01282.19 CDO71557.1 - 5.2e-33 112.8 0.0 1e-32 111.9 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e DUF4870 PF09685.10 CDO71558.1 - 0.11 12.6 1.9 0.16 12.1 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) HEAT PF02985.22 CDO71561.1 - 4.9e-41 135.2 18.3 0.0019 18.3 0.0 12.7 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 CDO71561.1 - 1.5e-35 121.4 13.7 2.5e-12 47.0 0.0 6.9 3 2 3 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.7 CDO71561.1 - 4.1e-14 53.0 1.5 3.3e-05 24.4 0.1 6.7 2 1 7 9 9 9 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CDO71561.1 - 2.9e-13 50.2 4.2 0.00085 19.4 0.1 5.2 2 2 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDO71561.1 - 2.6e-12 47.0 6.8 0.021 15.3 0.0 8.6 7 2 3 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.20 CDO71561.1 - 7.2e-11 41.3 2.5 6.1e-07 28.4 0.8 3.9 2 1 1 3 3 3 2 Adaptin N terminal region TAF6_C PF07571.13 CDO71561.1 - 5.8e-07 29.8 0.1 0.018 15.4 0.0 4.2 4 0 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 CDO71561.1 - 3.7e-05 23.4 1.0 0.32 10.5 0.1 4.6 2 1 3 5 5 5 1 CLASP N terminal Arm PF00514.23 CDO71561.1 - 5.3e-05 23.1 6.9 3.5 7.8 0.0 6.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Peripla_BP_2 PF01497.18 CDO71561.1 - 0.003 17.1 0.1 0.0069 16.0 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein IFRD PF05004.13 CDO71561.1 - 0.014 14.6 4.2 0.32 10.1 0.1 3.9 4 2 1 5 5 5 0 Interferon-related developmental regulator (IFRD) Ecm29 PF13001.7 CDO71561.1 - 0.036 12.8 7.6 1.9 7.0 0.0 4.4 4 2 0 4 4 4 0 Proteasome stabiliser HEAT_PBS PF03130.16 CDO71561.1 - 0.045 14.4 5.1 11 7.0 0.3 5.6 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat DUF1357 PF07094.11 CDO71561.1 - 0.12 12.4 0.4 0.88 9.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1357) Cohesin_HEAT PF12765.7 CDO71561.1 - 0.32 11.3 2.3 1.7e+02 2.7 0.2 4.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Aldose_epim PF01263.20 CDO71562.1 - 3.8e-29 101.9 0.5 4.5e-29 101.7 0.5 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DNA_pol_B PF00136.21 CDO71563.1 - 4.3e-104 348.8 0.0 6e-104 348.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CDO71563.1 - 8.8e-20 71.1 0.0 8e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CDO71563.1 - 2.6e-15 56.6 5.1 5.5e-15 55.6 5.1 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CDO71563.1 - 0.14 11.0 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral RecR PF02132.15 CDO71563.1 - 0.18 11.4 1.7 0.47 10.1 1.7 1.7 1 0 0 1 1 1 0 RecR protein AGTRAP PF06396.11 CDO71564.1 - 0.0059 16.4 1.5 0.028 14.2 1.5 2.0 1 1 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Peptidase_A22B PF04258.13 CDO71564.1 - 0.03 13.8 0.4 0.042 13.4 0.4 1.2 1 0 0 1 1 1 0 Signal peptide peptidase Glyco_transf_41 PF13844.6 CDO71565.1 - 1.2e-68 231.7 0.1 5.4e-38 130.6 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 41 TPR_17 PF13431.6 CDO71565.1 - 3.5e-10 39.5 1.0 0.36 11.3 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDO71565.1 - 1.1e-09 37.6 0.2 0.02 14.7 0.0 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO71565.1 - 4.6e-07 29.4 4.9 0.44 10.3 0.0 6.1 5 1 1 6 6 6 2 TPR repeat TPR_2 PF07719.17 CDO71565.1 - 1.8e-06 27.6 0.4 0.56 10.5 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDO71565.1 - 9.7e-06 25.4 0.2 6.7 7.2 0.2 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDO71565.1 - 0.0012 19.1 8.8 0.3 11.4 0.2 4.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDO71565.1 - 0.0068 17.1 0.2 52 5.0 0.0 4.9 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDO71565.1 - 0.015 15.2 5.5 9.4 6.3 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDO71565.1 - 0.022 15.3 1.6 7 7.2 0.1 4.0 3 2 2 5 5 5 0 Tetratricopeptide repeat TAL_FSA PF00923.19 CDO71567.1 - 2.5e-32 112.4 0.0 1.7e-31 109.6 0.0 2.0 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Med20 PF08612.11 CDO71568.1 - 0.00093 18.6 0.0 0.00093 18.6 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex WD40 PF00400.32 CDO71569.1 - 0.022 15.6 13.3 1.2 10.2 0.5 5.1 5 2 0 5 5 5 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO71569.1 - 0.066 13.5 0.0 15 6.0 0.0 2.7 2 2 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TMEM135_C_rich PF15982.5 CDO71570.1 - 5.4e-06 27.1 0.2 1.4e-05 25.7 0.1 1.7 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 ATP-synt_C PF00137.21 CDO71570.1 - 2.9 8.3 9.5 1.6 9.2 1.1 2.9 3 0 0 3 3 3 0 ATP synthase subunit C Pex24p PF06398.11 CDO71571.1 - 2.3e-08 33.4 0.9 2.9e-08 33.1 0.9 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HA2 PF04408.23 CDO71572.1 - 3.2e-18 66.0 0.0 8.8e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDO71572.1 - 4e-13 49.7 0.0 1e-12 48.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 CDO71572.1 - 6.3e-13 49.2 0.0 2e-05 25.2 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 CDO71572.1 - 2.1e-07 30.9 0.1 4.6e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CDO71572.1 - 1.8e-05 25.1 0.0 4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 CDO71572.1 - 1.9e-05 24.9 0.0 4.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 CDO71572.1 - 0.017 15.4 0.1 0.063 13.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 CDO71572.1 - 0.062 13.3 0.1 0.57 10.2 0.1 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Adaptin_N PF01602.20 CDO71573.1 - 9.5e-128 427.0 5.4 1.3e-127 426.6 5.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CDO71573.1 - 7e-39 132.5 0.0 1.5e-38 131.5 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 CDO71573.1 - 4.1e-13 49.6 0.1 9.2e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CDO71573.1 - 3.6e-06 27.1 2.0 0.00074 19.6 0.1 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDO71573.1 - 0.016 15.4 2.5 1.7 9.2 0.0 4.2 5 0 0 5 5 5 0 HEAT repeat Vitellogenin_N PF01347.22 CDO71573.1 - 0.029 12.8 0.2 0.047 12.1 0.2 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region RTP1_C1 PF10363.9 CDO71573.1 - 0.11 12.7 2.0 0.45 10.7 0.3 2.6 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGAP PF00616.19 CDO71574.1 - 2.6e-28 99.1 0.0 6.2e-25 88.1 0.0 2.3 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 CDO71574.1 - 2.8e-12 46.8 0.0 4.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain PH PF00169.29 CDO71574.1 - 0.018 15.5 0.0 0.057 13.9 0.0 1.8 2 0 0 2 2 2 0 PH domain ELO PF01151.18 CDO71575.1 - 1.2e-60 205.1 19.8 1.4e-60 205.0 19.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family HemY_N PF07219.13 CDO71576.1 - 0.061 13.5 2.4 0.16 12.2 2.4 1.7 1 0 0 1 1 1 0 HemY protein N-terminus Spc7 PF08317.11 CDO71576.1 - 0.18 10.6 1.5 0.27 10.1 1.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein VPS13_mid_rpt PF16910.5 CDO71578.1 - 4e-97 324.3 7.6 1.7e-92 309.2 0.3 5.1 3 1 1 4 4 4 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 CDO71578.1 - 4.5e-67 226.3 0.0 3.1e-64 217.0 0.0 2.7 2 1 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 CDO71578.1 - 1.8e-62 210.3 10.5 1.3e-46 158.7 0.1 4.1 4 0 0 4 4 4 3 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CDO71578.1 - 5e-50 170.5 12.5 2.4e-45 155.2 5.6 5.3 3 1 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CDO71578.1 - 3.9e-30 104.3 0.1 1.6e-29 102.4 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 CDO71578.1 - 1.3e-09 38.3 0.0 1.4e-08 34.9 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain SR-25 PF10500.9 CDO71578.1 - 0.12 11.9 2.0 0.3 10.7 2.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3040 PF11239.8 CDO71578.1 - 0.85 9.9 2.5 1.5 9.1 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DENN PF02141.21 CDO71579.1 - 7.1e-18 65.2 0.0 1.8e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain ATG16 PF08614.11 CDO71579.1 - 0.0013 19.0 11.6 0.0013 19.0 11.6 2.6 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) TMCO5 PF14992.6 CDO71579.1 - 0.094 12.3 9.1 0.19 11.3 9.1 1.4 1 0 0 1 1 1 0 TMCO5 family EspB_PE PF18625.1 CDO71579.1 - 0.14 12.6 2.6 0.27 11.7 0.2 2.9 2 1 1 3 3 3 0 ESX-1 secreted protein B PE domain SLATT_1 PF18181.1 CDO71579.1 - 0.49 10.3 4.1 1.1 9.2 4.1 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 IFT20 PF14931.6 CDO71579.1 - 0.52 10.5 13.3 1.3 9.3 13.3 1.7 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 PhosphMutase PF10143.9 CDO71579.1 - 0.71 9.7 2.7 1.5 8.6 2.7 1.5 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Zw10 PF06248.13 CDO71579.1 - 1.6 7.2 9.2 2.5 6.5 9.2 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 APG6_N PF17675.1 CDO71579.1 - 2.6 8.6 22.7 0.062 13.8 14.0 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF724 PF05266.14 CDO71579.1 - 3 7.6 20.0 0.077 12.8 9.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.15 CDO71579.1 - 9.9 5.6 13.5 1.1 8.8 7.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Mg_trans_NIPA PF05653.14 CDO71580.1 - 8.4e-12 44.8 14.9 4.8e-09 35.7 4.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 CDO71580.1 - 0.016 15.4 6.5 0.016 15.4 6.5 3.5 3 0 0 3 3 3 0 EamA-like transporter family AAA_2 PF07724.14 CDO71582.1 - 6e-51 173.0 0.0 2.1e-47 161.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CDO71582.1 - 3.6e-33 113.6 2.0 3.6e-33 113.6 2.0 3.8 4 1 0 4 4 3 1 AAA lid domain ClpB_D2-small PF10431.9 CDO71582.1 - 1.3e-26 92.4 2.9 1.4e-26 92.3 0.6 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CDO71582.1 - 1.6e-23 83.6 0.0 1.3e-12 48.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDO71582.1 - 8.8e-14 51.7 0.0 2.1e-06 27.8 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CDO71582.1 - 1.2e-13 51.0 3.9 1.6e-09 37.8 0.1 4.1 3 1 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 CDO71582.1 - 9.4e-12 45.6 2.4 5.1e-06 27.0 0.0 4.8 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 CDO71582.1 - 2e-08 34.6 0.0 0.036 14.3 0.0 4.2 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 CDO71582.1 - 6e-08 32.6 0.0 0.00012 21.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 CDO71582.1 - 4.5e-06 26.5 0.0 0.0022 17.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CDO71582.1 - 4.1e-05 23.0 0.0 0.037 13.4 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CDO71582.1 - 4.2e-05 22.9 0.2 0.32 10.2 0.0 3.0 2 1 1 3 3 3 2 TIP49 P-loop domain RNA_helicase PF00910.22 CDO71582.1 - 9.7e-05 22.7 0.0 1 9.8 0.0 2.8 3 0 0 3 3 2 2 RNA helicase TniB PF05621.11 CDO71582.1 - 0.00014 21.4 0.0 0.084 12.3 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_24 PF13479.6 CDO71582.1 - 0.00036 20.3 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDO71582.1 - 0.00056 19.5 0.0 0.66 9.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 CDO71582.1 - 0.00069 20.2 0.2 0.69 10.5 0.0 3.5 4 0 0 4 4 2 1 AAA domain RuvB_N PF05496.12 CDO71582.1 - 0.0008 19.2 0.2 1.9 8.2 0.0 4.4 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CDO71582.1 - 0.0012 19.0 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CDO71582.1 - 0.0086 16.0 0.3 5.4 6.9 0.1 3.5 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CDO71582.1 - 0.018 14.3 0.0 2.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Torsin PF06309.11 CDO71582.1 - 0.022 14.9 0.0 0.45 10.6 0.0 2.5 3 0 0 3 3 2 0 Torsin NACHT PF05729.12 CDO71582.1 - 0.042 13.8 0.0 0.97 9.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 CDO71582.1 - 0.043 13.6 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.15 CDO71582.1 - 0.048 13.7 0.0 0.48 10.4 0.0 2.4 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 CDO71582.1 - 0.051 13.5 0.0 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase PhoH PF02562.16 CDO71582.1 - 0.08 12.4 0.0 3.8 6.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 CDO71582.1 - 0.083 12.9 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CDO71582.1 - 0.097 13.2 0.1 20 5.7 0.0 2.9 3 0 0 3 3 2 0 ABC transporter CRS1_YhbY PF01985.21 CDO71582.1 - 0.11 12.7 0.0 1.5 9.0 0.0 2.9 3 0 0 3 3 2 0 CRS1 / YhbY (CRM) domain AAA_28 PF13521.6 CDO71582.1 - 0.17 12.1 2.9 8.8 6.5 0.0 3.5 3 1 0 3 3 3 0 AAA domain Roc PF08477.13 CDO71582.1 - 0.21 11.8 0.0 4.9 7.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CDO71582.1 - 0.42 11.1 11.2 12 6.3 0.0 3.6 3 2 0 3 3 3 0 AAA domain DUF4407 PF14362.6 CDO71582.1 - 0.9 8.8 8.3 1.7 7.9 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PV-1 PF06637.11 CDO71582.1 - 1 8.1 7.6 1.8 7.3 7.6 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) zf-CHCC PF10276.9 CDO71583.1 - 1.4e-08 34.6 0.1 2.3e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger domain Pkinase PF00069.25 CDO71584.1 - 1.4e-51 175.4 0.0 2.3e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71584.1 - 7.5e-22 77.9 0.0 1.5e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pannexin_like PF12534.8 CDO71584.1 - 0.31 10.1 0.5 0.49 9.4 0.5 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Pribosyl_synth PF14572.6 CDO71585.1 - 2.3e-40 138.6 4.1 4.5e-35 121.3 0.6 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CDO71585.1 - 4.6e-39 133.0 0.5 2.9e-38 130.4 0.2 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CDO71585.1 - 4.3e-15 55.6 0.1 8.7e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CDO71585.1 - 0.0024 17.3 0.1 0.004 16.6 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase FAD_binding_4 PF01565.23 CDO71586.1 - 2.2e-19 69.6 2.3 4.5e-19 68.6 2.3 1.5 1 0 0 1 1 1 1 FAD binding domain DCP2 PF05026.13 CDO71587.1 - 4.9e-32 110.1 1.5 7.9e-32 109.4 1.5 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 CDO71587.1 - 7.4e-13 48.7 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SLAC1 PF03595.17 CDO71588.1 - 0.046 13.0 3.2 0.24 10.6 0.0 2.1 2 0 0 2 2 2 0 Voltage-dependent anion channel DUF3292 PF11696.8 CDO71588.1 - 0.07 11.5 2.4 16 3.7 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3292) PH_TFIIH PF08567.11 CDO71588.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Reticulon PF02453.17 CDO71588.1 - 0.15 12.1 0.6 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 Reticulon Rad21_Rec8_N PF04825.13 CDO71589.1 - 5.1e-16 58.8 0.0 8.5e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CDO71589.1 - 2.8e-11 42.5 0.0 5.4e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein NUDIX PF00293.28 CDO71590.1 - 1.2e-25 90.1 0.0 1.8e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MPC PF03650.13 CDO71594.1 - 9.1e-35 119.1 0.3 1.1e-34 118.8 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DNA_ligase_A_M PF01068.21 CDO71595.1 - 1.1e-65 221.1 0.1 1.9e-65 220.3 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CDO71595.1 - 2.8e-46 158.0 0.9 6.6e-46 156.8 0.9 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CDO71595.1 - 8e-27 93.8 0.0 2e-26 92.4 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CDO71595.1 - 0.00045 20.6 0.1 0.00085 19.7 0.1 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 CDO71595.1 - 0.0057 16.6 0.1 1.4 9.0 0.0 2.6 2 0 0 2 2 2 2 DNA ligase OB-like domain eIF-3c_N PF05470.12 CDO71595.1 - 0.032 12.5 0.0 0.072 11.4 0.0 1.6 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Salp15 PF12115.8 CDO71595.1 - 0.11 12.9 0.0 0.67 10.4 0.0 2.2 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF3377 PF11857.8 CDO71597.1 - 0.054 13.4 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Ribosomal_S17 PF00366.20 CDO71598.1 - 3.9e-28 97.3 0.5 6.9e-28 96.5 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 CDO71598.1 - 1.2e-24 86.5 0.1 2.2e-24 85.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal OmdA PF13376.6 CDO71598.1 - 0.029 14.4 0.6 5.9 7.0 0.1 2.3 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Metallophos PF00149.28 CDO71599.1 - 2.3e-38 132.8 0.0 1.4e-37 130.2 0.0 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDO71599.1 - 3.9e-18 65.6 0.1 8.4e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Peptidase_S8 PF00082.22 CDO71600.1 - 4.2e-29 101.7 17.6 1e-28 100.5 17.5 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CDO71600.1 - 1e-06 29.3 0.1 1.7e-05 25.4 0.0 2.7 2 1 0 2 2 2 1 Peptidase inhibitor I9 EamA PF00892.20 CDO71601.1 - 0.03 14.5 2.9 0.03 14.5 2.9 3.1 3 0 0 3 3 3 0 EamA-like transporter family RTA1 PF04479.13 CDO71602.1 - 1e-26 93.8 2.6 2.1e-18 66.7 0.2 2.1 2 0 0 2 2 2 2 RTA1 like protein RTA1 PF04479.13 CDO71603.1 - 2e-58 197.4 4.9 3e-58 196.8 4.9 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3149 PF11346.8 CDO71603.1 - 0.42 10.3 6.4 0.074 12.7 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) SGS PF05002.15 CDO71604.1 - 1.9e-35 120.8 3.6 2.9e-35 120.2 3.6 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.16 CDO71604.1 - 5.1e-09 37.0 0.5 7.2e-09 36.6 0.0 1.5 2 0 0 2 2 2 1 CS domain GST_N_3 PF13417.6 CDO71605.1 - 2.7e-13 50.1 0.1 1.5e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO71605.1 - 2.2e-08 34.2 0.0 4.4e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO71605.1 - 7.1e-05 23.1 0.0 0.00023 21.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDO71605.1 - 0.00011 22.4 0.1 0.0039 17.3 0.0 3.2 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO71605.1 - 0.00032 20.7 0.2 0.0019 18.2 0.1 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDO71605.1 - 0.002 18.3 0.1 0.0074 16.5 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Galactosyl_T PF01762.21 CDO71606.1 - 8.2e-06 25.8 0.0 0.00068 19.5 0.0 2.6 3 0 0 3 3 3 2 Galactosyltransferase CsbD PF05532.12 CDO71609.1 - 0.13 12.2 1.0 0.29 11.1 1.0 1.6 1 0 0 1 1 1 0 CsbD-like OppC_N PF12911.7 CDO71611.1 - 0.0064 16.5 0.5 0.014 15.3 0.5 1.5 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C PMP1_2 PF08114.11 CDO71611.1 - 0.14 11.9 0.8 0.25 11.1 0.8 1.3 1 0 0 1 1 1 0 ATPase proteolipid family ADH_zinc_N_2 PF13602.6 CDO71612.1 - 2e-21 77.4 0.0 2.6e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Isochorismatase PF00857.20 CDO71613.1 - 2.4e-23 83.2 0.0 5.3e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family SKG6 PF08693.10 CDO71614.1 - 0.3 10.5 2.8 0.69 9.4 2.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ras PF00071.22 CDO71615.1 - 2.3e-14 53.3 0.2 2.9e-14 53.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO71615.1 - 1.1e-10 41.8 0.1 1.3e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 CDO71615.1 - 0.00016 21.3 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 CDO71615.1 - 0.00028 20.3 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 CDO71615.1 - 0.00095 19.5 0.1 0.0011 19.2 0.1 1.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CDO71615.1 - 0.0014 18.5 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain DAP3 PF10236.9 CDO71615.1 - 0.0078 15.4 0.0 0.009 15.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CDO71615.1 - 0.01 16.2 0.0 0.01 16.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 CDO71615.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_30 PF13604.6 CDO71615.1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CDO71615.1 - 0.013 14.8 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Septin Sigma54_activat PF00158.26 CDO71615.1 - 0.018 14.7 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.9 CDO71615.1 - 0.023 13.9 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CDO71615.1 - 0.029 14.7 0.0 0.036 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDO71615.1 - 0.034 13.6 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 CDO71615.1 - 0.037 14.6 0.1 0.042 14.4 0.1 1.1 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 CDO71615.1 - 0.052 13.0 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 CDO71615.1 - 0.061 13.0 0.0 0.065 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 CDO71615.1 - 0.073 13.1 0.0 0.077 13.0 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 CDO71615.1 - 0.081 12.7 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 CDO71615.1 - 0.098 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 CDO71615.1 - 0.16 11.6 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_S8 PF00082.22 CDO71616.1 - 3e-12 46.4 0.2 3.1e-12 46.4 0.2 1.0 1 0 0 1 1 1 1 Subtilase family D-ser_dehydrat PF14031.6 CDO71617.1 - 1e-25 90.2 0.0 1.5e-24 86.5 0.0 2.7 3 1 0 3 3 3 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CDO71617.1 - 2.1e-15 57.0 0.1 3e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Abhydrolase_3 PF07859.13 CDO71618.1 - 1.2e-42 146.2 0.0 1.7e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO71618.1 - 0.00035 21.3 0.3 0.00046 20.9 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CDO71618.1 - 0.00043 19.8 0.0 0.0037 16.8 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 CDO71618.1 - 0.016 14.1 2.0 0.55 9.0 0.2 2.1 1 1 1 2 2 2 0 Carboxylesterase family IlvN PF07991.12 CDO71619.1 - 1.3e-51 174.4 0.1 2e-51 173.9 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain RRM_1 PF00076.22 CDO71619.1 - 2.2e-43 146.0 0.1 6.3e-21 74.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CDO71619.1 - 3.9e-13 50.3 2.8 1.2e-11 45.6 2.8 2.6 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein IlvC PF01450.19 CDO71619.1 - 2.5e-11 44.0 0.9 3.2e-09 37.2 0.1 2.3 1 1 1 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 CDO71619.1 - 5.2e-11 43.0 0.1 1.1e-10 41.9 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CDO71619.1 - 2.8e-06 27.6 0.0 5.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RRM_3 PF08777.11 CDO71619.1 - 1.6e-05 24.9 0.2 0.0061 16.6 0.0 2.7 2 0 0 2 2 2 1 RNA binding motif 2-Hacid_dh_C PF02826.19 CDO71619.1 - 4.9e-05 22.8 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_occluded PF16842.5 CDO71619.1 - 9.6e-05 22.2 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CDO71619.1 - 0.027 14.0 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Shikimate_DH PF01488.20 CDO71619.1 - 0.033 14.3 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 CDO71619.1 - 0.039 13.9 0.1 0.16 11.9 0.1 1.9 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Nup35_RRM_2 PF14605.6 CDO71619.1 - 0.058 13.4 0.1 3.5 7.7 0.0 2.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PDH PF02153.17 CDO71619.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase adh_short_C2 PF13561.6 CDO71620.1 - 4.8e-48 163.8 0.0 5.4e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO71620.1 - 4.2e-31 107.9 0.1 5.5e-31 107.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO71620.1 - 8e-05 22.6 0.0 0.00036 20.5 0.0 1.9 1 1 0 1 1 1 1 KR domain Cupin_2 PF07883.11 CDO71621.1 - 0.0003 20.4 0.0 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Pex16 PF08610.10 CDO71622.1 - 1.3e-114 382.8 1.0 1.4e-114 382.6 1.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) OmpH PF03938.14 CDO71623.1 - 0.14 12.5 8.7 0.24 11.7 8.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RRP36 PF06102.12 CDO71624.1 - 6.2e-41 140.1 22.9 6.2e-41 140.1 22.9 3.5 4 0 0 4 4 4 1 rRNA biogenesis protein RRP36 CorA PF01544.18 CDO71624.1 - 1.8e-18 66.9 7.3 3e-12 46.5 0.2 3.4 2 1 1 3 3 3 2 CorA-like Mg2+ transporter protein Ninjurin PF04923.12 CDO71624.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Ninjurin FAM177 PF14774.6 CDO71624.1 - 0.13 12.7 1.7 0.36 11.2 0.1 2.4 2 0 0 2 2 2 0 FAM177 family Zip PF02535.22 CDO71624.1 - 2.8 7.1 5.0 0.81 8.8 0.1 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter FMN_red PF03358.15 CDO71625.1 - 5.2e-23 81.5 0.0 8.5e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CDO71625.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold DUF2235 PF09994.9 CDO71627.1 - 3.6e-31 108.6 0.1 6.1e-31 107.8 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SNAP PF14938.6 CDO71628.1 - 5.9e-108 360.6 17.3 6.7e-108 360.4 17.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 CDO71628.1 - 3.2e-06 26.8 5.7 0.017 15.1 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDO71628.1 - 0.0002 21.6 18.0 0.00026 21.2 6.9 3.6 1 1 3 4 4 4 1 Tetratricopeptide repeat Spatacsin_C PF14649.6 CDO71628.1 - 0.0051 16.0 9.0 0.015 14.5 7.6 2.2 1 1 1 2 2 2 1 Spatacsin C-terminus TPR_6 PF13174.6 CDO71628.1 - 0.0059 17.2 11.2 3.1 8.6 0.1 6.0 4 2 0 5 5 5 1 Tetratricopeptide repeat TC1 PF15063.6 CDO71628.1 - 0.017 14.9 0.4 0.058 13.3 0.4 2.0 1 0 0 1 1 1 0 Thyroid cancer protein 1 TPR_8 PF13181.6 CDO71628.1 - 0.045 14.0 0.1 0.045 14.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDO71628.1 - 0.069 12.8 8.4 5.7 6.7 0.2 4.9 5 0 0 5 5 5 0 TPR repeat DUF4351 PF14261.6 CDO71628.1 - 0.089 12.9 0.2 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) THDPS_N_2 PF14805.6 CDO71628.1 - 0.19 11.9 2.7 1.1 9.5 0.0 2.9 2 1 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal PerC PF06069.11 CDO71628.1 - 0.43 10.9 2.7 6.9 7.0 0.1 2.7 1 1 1 2 2 2 0 PerC transcriptional activator TPR_2 PF07719.17 CDO71628.1 - 0.77 10.0 19.9 2.4 8.5 1.0 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat Rotamase PF00639.21 CDO71628.1 - 3.4 8.7 5.1 1.1 10.2 0.2 2.5 2 1 0 2 2 2 0 PPIC-type PPIASE domain PGM_PMM_I PF02878.16 CDO71629.1 - 2.3e-11 43.6 0.1 2.3e-07 30.6 0.0 2.8 3 0 0 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CDO71629.1 - 3.5e-10 39.9 0.7 8.1e-10 38.7 0.3 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 CDO71629.1 - 0.0036 17.9 0.1 0.018 15.7 0.1 2.3 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II GATase_4 PF13230.6 CDO71630.1 - 7.2e-16 57.9 0.0 1.9e-15 56.5 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 CDO71630.1 - 6e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DS PF01916.17 CDO71631.1 - 3.8e-46 157.6 0.1 4.4e-46 157.4 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Lectin_like PF18560.1 CDO71631.1 - 0.023 14.9 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 Lectin like domain APH PF01636.23 CDO71632.1 - 2.6e-17 63.6 0.0 1.2e-16 61.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CDO71632.1 - 0.0018 17.3 0.0 0.0074 15.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) RIO1 PF01163.22 CDO71632.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.6 1 1 0 1 1 1 0 RIO1 family GATase_4 PF13230.6 CDO71633.1 - 3.1e-07 29.6 0.1 8.7e-07 28.1 0.1 1.6 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 CDO71633.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain ICE2 PF08426.10 CDO71634.1 - 8.1e-31 107.5 25.6 5.9e-17 61.9 13.8 2.9 2 1 0 2 2 2 2 ICE2 MoaE PF02391.17 CDO71635.1 - 3.2e-37 127.3 1.6 2.7e-36 124.3 1.6 2.0 1 1 0 1 1 1 1 MoaE protein RIF5_SNase_1 PF18187.1 CDO71635.1 - 0.017 14.9 0.2 0.052 13.3 0.2 1.8 1 1 0 1 1 1 0 TbRIF5 SNase domain 1 RmuC PF02646.16 CDO71635.1 - 0.051 12.7 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 RmuC family Indigoidine_A PF04227.12 CDO71636.1 - 6.1e-127 423.0 0.1 9.9e-127 422.3 0.1 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 CDO71636.1 - 2.8e-21 76.1 0.8 4.4e-11 42.6 0.1 2.5 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Helicase_C PF00271.31 CDO71637.1 - 1.1e-13 51.5 0.0 2.9e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO71637.1 - 7.8e-05 22.7 0.1 0.001 19.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDO71637.1 - 0.0086 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CDO71637.1 - 0.043 13.0 0.3 0.098 11.9 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Cgr1 PF03879.14 CDO71637.1 - 0.7 10.3 9.3 1.3 9.4 9.3 1.3 1 0 0 1 1 1 0 Cgr1 family Mito_carr PF00153.27 CDO71638.1 - 2.5e-66 219.6 5.8 2.1e-23 82.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CS PF04969.16 CDO71639.1 - 4e-18 66.2 0.4 1.2e-17 64.7 0.4 1.9 1 1 0 1 1 1 1 CS domain DUF2187 PF09953.9 CDO71640.1 - 0.00041 20.3 0.2 4.7 7.3 0.0 3.2 3 0 0 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2187) DUF4720 PF15846.5 CDO71640.1 - 0.0051 16.6 0.1 0.14 12.0 0.0 2.5 1 1 0 2 2 2 1 Domain of unknown function (DUF4720) NUC153 PF08159.12 CDO71641.1 - 7.2e-13 48.1 15.5 3.8e-12 45.8 0.9 3.8 3 0 0 3 3 3 3 NUC153 domain Tim17 PF02466.19 CDO71643.1 - 7.7e-06 26.3 10.1 1.4e-05 25.4 10.0 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_S9 PF00380.19 CDO71644.1 - 1e-27 97.1 0.5 1e-27 97.1 0.5 1.9 2 0 0 2 2 1 1 Ribosomal protein S9/S16 BRCT_2 PF16589.5 CDO71644.1 - 3.5e-20 72.2 0.0 7.8e-16 58.3 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CDO71644.1 - 1.2e-05 25.6 0.0 4.1e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain CDC45 PF02724.14 CDO71644.1 - 0.0032 15.9 5.2 0.0046 15.3 5.2 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 CDO71644.1 - 0.038 12.2 10.1 0.058 11.6 10.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2052 PF09747.9 CDO71644.1 - 0.23 11.6 9.3 0.49 10.5 7.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Nop53 PF07767.11 CDO71644.1 - 1.1 8.6 18.3 0.41 10.0 14.5 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Hid1 PF12722.7 CDO71644.1 - 2.2 6.3 3.5 3.5 5.6 3.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apt1 PF10351.9 CDO71644.1 - 2.8 6.7 10.8 0.018 13.9 2.1 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain TFIIF_alpha PF05793.12 CDO71644.1 - 3.1 6.3 19.8 5.1 5.6 19.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SWIRM-assoc_2 PF16496.5 CDO71644.1 - 3.5 6.4 12.7 40 2.9 0.0 2.3 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal NOA36 PF06524.12 CDO71644.1 - 7.9 5.7 7.7 16 4.7 7.7 1.4 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L4 PF00573.22 CDO71645.1 - 2.1e-64 216.7 0.0 2.4e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF697 PF05128.12 CDO71645.1 - 0.074 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF697) Rad51 PF08423.11 CDO71646.1 - 2.6e-123 410.3 0.0 3.2e-123 410.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CDO71646.1 - 2.8e-10 40.1 0.0 3.7e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CDO71646.1 - 2.6e-09 37.0 0.1 3.6e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 CDO71646.1 - 5.5e-08 33.3 1.1 2.7e-07 31.1 0.7 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 CDO71646.1 - 6.1e-05 22.5 0.0 0.00019 20.9 0.0 1.8 1 1 0 1 1 1 1 KaiC HHH PF00633.23 CDO71646.1 - 0.048 13.5 0.1 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif 2-Hacid_dh_C PF02826.19 CDO71647.1 - 8.5e-54 181.6 0.0 1.7e-53 180.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CDO71647.1 - 9.8e-35 119.1 0.0 1.4e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CDO71647.1 - 0.00085 19.5 0.2 0.0067 16.6 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 CDO71647.1 - 0.0058 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATase PF00117.28 CDO71648.1 - 2.4e-19 69.8 0.0 3.6e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I His_biosynth PF00977.21 CDO71648.1 - 1.9e-15 56.9 0.3 4.8e-15 55.7 0.3 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein SNO PF01174.19 CDO71648.1 - 1.7e-08 34.5 0.0 1.9e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 CDO71648.1 - 5.4e-06 26.1 0.0 8.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 CDO71648.1 - 0.016 14.9 0.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 Pal1 PF08316.11 CDO71649.1 - 1e-14 55.5 0.1 2.8e-14 54.0 0.1 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein Meth_synt_2 PF01717.18 CDO71650.1 - 3.1e-05 23.4 0.0 0.15 11.3 0.0 2.7 2 1 1 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CDO71650.1 - 0.003 17.1 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Ribosomal_L13e PF01294.18 CDO71651.1 - 2.6e-76 255.5 4.8 3.8e-76 255.0 4.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e FA_desaturase PF00487.24 CDO71652.1 - 3.4e-25 89.3 26.2 4.9e-25 88.8 26.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CDO71652.1 - 9e-08 32.2 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF5485 PF17586.2 CDO71652.1 - 0.063 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5485) Sugar_tr PF00083.24 CDO71653.1 - 0.0056 15.6 1.0 0.012 14.5 0.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Podoplanin PF05808.11 CDO71653.1 - 0.043 13.9 0.7 0.07 13.2 0.7 1.3 1 0 0 1 1 1 0 Podoplanin CD34_antigen PF06365.12 CDO71653.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF3123 PF11321.8 CDO71653.1 - 3.7 8.3 8.1 0.67 10.6 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) MGC-24 PF05283.11 CDO71653.1 - 6.9 7.1 8.9 0.82 10.1 2.6 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin WD40 PF00400.32 CDO71656.1 - 1.9e-43 145.6 12.8 2.3e-07 31.4 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CDO71656.1 - 2.8e-32 111.7 0.0 5.7e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CDO71656.1 - 4.1e-12 46.2 0.0 0.00023 21.4 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDO71656.1 - 2.2e-05 23.3 3.5 0.58 8.7 0.0 4.9 2 1 3 5 5 5 2 Nucleoporin Nup120/160 LisH PF08513.11 CDO71656.1 - 0.0023 17.8 0.1 0.0093 15.9 0.1 2.0 2 0 0 2 2 2 1 LisH eIF2A PF08662.11 CDO71656.1 - 0.0036 17.2 0.0 0.029 14.2 0.0 2.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A ELYS-bb PF16687.5 CDO71656.1 - 0.0046 15.6 0.0 0.0094 14.6 0.0 1.4 1 0 0 1 1 1 1 beta-propeller of ELYS nucleoporin Ge1_WD40 PF16529.5 CDO71656.1 - 0.0049 15.9 0.0 0.79 8.6 0.0 3.5 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CDO71656.1 - 0.028 13.0 0.0 0.046 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain GOLD_2 PF13897.6 CDO71657.1 - 0.53 10.8 2.1 1.9 9.0 0.1 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Plavaka PF18759.1 CDO71658.1 - 1.1e-120 402.8 0.0 1.5e-120 402.4 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase MSA_2 PF00985.17 CDO71658.1 - 0.13 12.6 0.2 0.22 11.9 0.2 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family FRG2 PF15315.6 CDO71659.1 - 0.02 15.1 5.4 0.027 14.7 5.4 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 SH3_1 PF00018.28 CDO71661.1 - 1.4e-07 31.0 0.0 2.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDO71661.1 - 2.5e-06 27.2 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDO71661.1 - 0.0015 18.2 0.0 0.0045 16.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Amnionless PF14828.6 CDO71661.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 CDO71661.1 - 0.36 10.6 3.9 0.62 9.9 3.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Nop PF01798.18 CDO71662.1 - 0.028 13.9 0.0 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin FYRN PF05964.14 CDO71663.1 - 2.9e-18 65.4 0.3 5.2e-18 64.6 0.3 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 CDO71663.1 - 6.4e-16 58.3 0.0 1.2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus DUF573 PF04504.14 CDO71663.1 - 0.15 12.7 0.3 0.31 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF573 CN_hydrolase PF00795.22 CDO71664.1 - 6.9e-14 51.8 0.0 9.1e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AMPK1_CBM PF16561.5 CDO71665.1 - 1.3e-18 67.0 0.0 2.3e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase TetR_C_12 PF16914.5 CDO71666.1 - 0.075 13.2 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial transcriptional repressor C-terminal Nop PF01798.18 CDO71666.1 - 0.081 12.4 0.0 1 8.8 0.0 2.0 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin BHD_3 PF10405.9 CDO71667.1 - 5.7e-27 93.9 0.1 1.2e-26 93.0 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 CDO71667.1 - 5.1e-25 87.9 0.0 1.6e-24 86.2 0.0 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 CDO71667.1 - 1.3e-19 70.9 0.4 1.3e-19 70.9 0.4 4.1 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 CDO71667.1 - 5.2e-19 67.8 0.0 1.1e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 CDO71667.1 - 4.7e-08 33.5 0.0 4.4e-06 27.1 0.0 2.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily TPR_14 PF13428.6 CDO71667.1 - 3.8 8.6 6.1 8.7 7.5 0.8 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GCD14 PF08704.10 CDO71668.1 - 2.5e-70 237.0 0.3 1.5e-64 218.1 0.0 2.6 2 1 1 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CDO71668.1 - 6.7e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDO71668.1 - 5.2e-05 23.1 0.0 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 CDO71668.1 - 0.0014 19.6 0.1 0.0032 18.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO71668.1 - 0.0021 18.7 0.0 0.0051 17.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 CDO71668.1 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Fibrillarin PF01269.17 CDO71668.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_4 PF02390.17 CDO71668.1 - 0.026 14.0 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 CDO71668.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CDO71668.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PAS_3 PF08447.12 CDO71669.1 - 1.3e-09 38.3 0.0 2.5e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 CDO71669.1 - 8.4e-06 25.8 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 CDO71669.1 - 0.00034 20.7 0.0 0.003 17.7 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 CDO71669.1 - 0.0022 18.2 0.0 0.033 14.4 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 CDO71669.1 - 0.097 12.9 0.0 0.77 10.0 0.0 2.1 2 0 0 2 2 2 0 PAS fold Helicase_C PF00271.31 CDO71670.1 - 2.2e-10 40.9 0.0 4.6e-09 36.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CDO71670.1 - 0.0087 16.8 1.2 0.016 15.9 0.2 2.1 2 0 0 2 2 2 1 RecQ zinc-binding HAD_2 PF13419.6 CDO71671.1 - 1.8e-16 60.8 0.0 1.9e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDO71671.1 - 1.3e-13 51.7 0.0 3.9e-13 50.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDO71671.1 - 3.7e-07 30.1 0.0 9.6e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like ADH_zinc_N PF00107.26 CDO71671.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Linker_histone PF00538.19 CDO71672.1 - 1.8e-07 31.4 0.0 3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 linker histone H1 and H5 family Ribonuc_L-PSP PF01042.21 CDO71673.1 - 2.4e-35 121.2 0.0 2.6e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP p450 PF00067.22 CDO71675.1 - 6.6e-78 262.5 0.0 8.2e-78 262.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 THOC7 PF05615.13 CDO71676.1 - 0.0038 17.5 0.0 0.005 17.1 0.0 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 CALCOCO1 PF07888.11 CDO71676.1 - 0.0054 15.7 0.8 0.0067 15.4 0.8 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CHASE3 PF05227.13 CDO71676.1 - 0.016 15.2 0.4 0.026 14.5 0.4 1.4 1 0 0 1 1 1 0 CHASE3 domain Spc7 PF08317.11 CDO71676.1 - 0.02 13.8 0.8 0.027 13.3 0.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Transcrip_act PF04949.13 CDO71676.1 - 0.024 14.5 0.4 0.093 12.6 0.4 1.7 1 1 1 2 2 2 0 Transcriptional activator Seryl_tRNA_N PF02403.22 CDO71676.1 - 0.039 14.2 0.7 0.064 13.5 0.7 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 CDO71676.1 - 0.048 14.1 1.1 0.14 12.6 0.7 1.9 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Filo_VP35 PF02097.15 CDO71676.1 - 0.073 12.1 0.2 0.1 11.6 0.2 1.1 1 0 0 1 1 1 0 Filoviridae VP35 DUF3349 PF11829.8 CDO71676.1 - 0.083 13.7 0.4 0.15 12.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) DUF3736 PF12540.8 CDO71676.1 - 0.095 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) DASH_Dam1 PF08653.10 CDO71676.1 - 0.11 12.3 0.1 0.35 10.7 0.1 1.9 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF1664 PF07889.12 CDO71676.1 - 0.14 12.2 0.9 0.23 11.5 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Carn_acyltransf PF00755.20 CDO71679.1 - 1.3e-194 648.1 0.1 1.5e-194 647.9 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PUL PF08324.11 CDO71680.1 - 3.7e-39 134.6 1.8 6.3e-39 133.9 1.8 1.3 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 CDO71680.1 - 6.9e-24 84.4 0.0 1.1e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 CDO71680.1 - 3.7e-15 55.8 0.0 8.6e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDO71680.1 - 1.3e-07 32.1 0.0 5.5e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CDO71680.1 - 0.0021 17.5 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 CDO71680.1 - 0.031 14.5 0.0 0.54 10.4 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.6 CDO71680.1 - 0.038 13.8 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 CDO71680.1 - 0.054 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin Redoxin PF08534.10 CDO71680.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Redoxin SSP160 PF06933.11 CDO71680.1 - 0.59 8.3 10.0 0.93 7.6 10.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 YqfQ PF14181.6 CDO71680.1 - 4.8 7.4 12.3 1.3 9.2 6.3 2.3 1 1 1 2 2 2 0 YqfQ-like protein p450 PF00067.22 CDO71681.1 - 1.7e-50 172.1 0.0 2.1e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 POP1 PF06978.11 CDO71682.1 - 1.9e-48 165.2 22.7 1.1e-27 97.3 4.7 2.8 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CDO71682.1 - 1.5e-34 118.2 0.3 1.5e-34 118.2 0.3 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 CDO71682.1 - 6e-05 22.5 0.0 0.11 11.9 0.0 2.6 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CDO71682.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DUF1761 PF08570.10 CDO71683.1 - 1.1 9.5 8.3 0.066 13.5 3.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) D123 PF07065.14 CDO71684.1 - 1.1e-92 310.4 0.0 1.5e-92 310.1 0.0 1.1 1 0 0 1 1 1 1 D123 Exo_endo_phos PF03372.23 CDO71685.1 - 0.00017 21.2 0.0 0.00047 19.8 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAD_binding_5 PF00941.21 CDO71685.1 - 0.071 12.8 0.1 0.35 10.6 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase Mito_carr PF00153.27 CDO71688.1 - 5e-74 244.3 0.1 1.2e-25 89.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NTP_transf_9 PF04248.12 CDO71689.1 - 4.5e-24 84.2 0.8 2.9e-21 75.2 0.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF427) 3Beta_HSD PF01073.19 CDO71693.1 - 2.5e-61 207.2 0.0 1.5e-57 194.8 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CDO71693.1 - 2.8e-34 118.7 0.0 3.8e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDO71693.1 - 1.1e-18 67.8 0.0 2.4e-14 53.5 0.0 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CDO71693.1 - 5.7e-13 48.6 0.0 4.1e-08 32.7 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 CDO71693.1 - 7e-11 41.8 0.0 1.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CDO71693.1 - 2.2e-10 40.8 0.0 3.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CDO71693.1 - 3.3e-05 23.2 0.1 0.00012 21.3 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CDO71693.1 - 0.0008 19.0 0.1 0.0072 15.9 0.1 2.0 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 CDO71693.1 - 0.022 14.6 0.2 0.06 13.3 0.2 1.8 1 1 0 1 1 1 0 KR domain AlkA_N PF06029.11 CDO71694.1 - 0.17 12.2 0.0 0.41 10.9 0.0 1.7 1 1 0 1 1 1 0 AlkA N-terminal domain EF_assoc_2 PF08356.12 CDO71695.1 - 1.8e-38 130.4 0.0 4e-38 129.3 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 CDO71695.1 - 2.7e-32 110.2 0.4 5.7e-32 109.1 0.4 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 CDO71695.1 - 8.9e-32 109.9 0.0 7.1e-20 71.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CDO71695.1 - 2.7e-18 66.3 0.0 9.8e-10 38.7 0.0 2.8 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 CDO71695.1 - 4.9e-11 42.9 0.1 0.00024 21.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CDO71695.1 - 5.2e-11 41.6 0.1 5.5e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain Arf PF00025.21 CDO71695.1 - 1.8e-10 40.5 0.0 0.00025 20.6 0.0 3.3 2 2 0 2 2 2 2 ADP-ribosylation factor family EF-hand_1 PF00036.32 CDO71695.1 - 4.5e-10 38.3 0.5 0.00037 19.8 0.0 2.8 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 CDO71695.1 - 7.2e-08 32.5 0.0 0.0051 16.9 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_5 PF13202.6 CDO71695.1 - 1e-07 31.1 2.0 0.0061 16.0 0.1 2.7 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.6 CDO71695.1 - 3.8e-06 27.4 0.1 0.14 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CDO71695.1 - 5.4e-06 26.7 0.2 0.039 14.2 0.0 3.0 2 2 0 2 2 2 2 AAA domain EF-hand_10 PF14788.6 CDO71695.1 - 7.6e-06 25.7 1.2 0.0075 16.1 0.1 2.5 2 0 0 2 2 2 2 EF hand Dynamin_N PF00350.23 CDO71695.1 - 9.6e-06 25.8 1.6 0.26 11.3 0.0 3.3 2 1 1 3 3 3 1 Dynamin family AAA_18 PF13238.6 CDO71695.1 - 3.4e-05 24.4 0.0 0.07 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CDO71695.1 - 5.5e-05 23.7 0.0 0.35 11.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 CDO71695.1 - 7e-05 22.8 0.1 0.26 11.2 0.0 3.4 4 0 0 4 4 3 1 RsgA GTPase AAA_33 PF13671.6 CDO71695.1 - 8.4e-05 22.8 0.0 0.54 10.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CDO71695.1 - 0.00013 21.6 0.1 0.085 12.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 CDO71695.1 - 0.00018 22.0 0.0 0.31 11.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CDO71695.1 - 0.00021 21.2 0.0 0.51 10.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain VirE PF05272.11 CDO71695.1 - 0.00028 20.7 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E Septin PF00735.18 CDO71695.1 - 0.00034 20.0 0.0 0.057 12.7 0.0 2.3 2 0 0 2 2 2 1 Septin ATP_bind_1 PF03029.17 CDO71695.1 - 0.00051 19.9 1.8 4.1 7.1 0.1 4.1 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 CDO71695.1 - 0.00055 20.2 0.0 0.54 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 CDO71695.1 - 0.00056 19.7 0.0 0.097 12.4 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CDO71695.1 - 0.00076 19.3 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 CDO71695.1 - 0.0011 18.3 0.0 1.6 7.8 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.22 CDO71695.1 - 0.0011 19.3 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SRPRB PF09439.10 CDO71695.1 - 0.0012 18.3 0.0 1 8.8 0.0 2.5 3 0 0 3 3 2 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CDO71695.1 - 0.0016 18.0 0.0 0.069 12.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region SPARC_Ca_bdg PF10591.9 CDO71695.1 - 0.0039 17.5 1.9 0.73 10.2 0.0 3.0 3 0 0 3 3 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF815 PF05673.13 CDO71695.1 - 0.0046 16.2 0.1 0.58 9.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MCM PF00493.23 CDO71695.1 - 0.0049 16.0 0.0 0.084 12.0 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_25 PF13481.6 CDO71695.1 - 0.0054 16.3 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_8 PF13833.6 CDO71695.1 - 0.0078 16.0 0.2 4.6 7.2 0.0 2.9 3 0 0 3 3 2 0 EF-hand domain pair Ploopntkinase3 PF18751.1 CDO71695.1 - 0.0092 15.9 0.0 3.2 7.6 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NOG1 PF06858.14 CDO71695.1 - 0.0094 15.7 0.2 2.1 8.2 0.1 3.2 3 0 0 3 3 3 1 Nucleolar GTP-binding protein 1 (NOG1) NB-ARC PF00931.22 CDO71695.1 - 0.012 14.8 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 CDO71695.1 - 0.016 15.0 0.0 0.5 10.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 CDO71695.1 - 0.021 15.4 0.1 3.8 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDO71695.1 - 0.022 14.7 0.0 0.79 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 CDO71695.1 - 0.023 14.0 0.1 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 CDO71695.1 - 0.027 14.1 0.4 3.5 7.2 0.0 3.0 2 2 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 CDO71695.1 - 0.032 14.2 0.0 6.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CDO71695.1 - 0.045 13.0 0.0 9.1 5.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin TniB PF05621.11 CDO71695.1 - 0.062 12.7 0.0 6.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 CDO71695.1 - 0.075 13.1 0.0 4.4 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 CDO71695.1 - 0.081 12.2 0.0 0.34 10.2 0.0 2.0 2 0 0 2 2 2 0 AIG1 family ATPase_2 PF01637.18 CDO71695.1 - 0.095 12.6 0.2 5.8 6.8 0.0 3.1 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 CDO71695.1 - 0.095 12.4 0.0 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CDO71695.1 - 0.2 11.4 0.0 3.8 7.2 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_15 PF13175.6 CDO71695.1 - 0.24 11.1 0.0 17 5.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain VWA PF00092.28 CDO71696.1 - 1.8e-10 41.3 0.0 3.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDO71696.1 - 5.4e-06 27.0 0.0 1.3e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 CDO71696.1 - 6.6e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A TRI5 PF06330.11 CDO71697.1 - 1e-09 37.8 0.0 1.5e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) XylR_N PF06505.11 CDO71697.1 - 0.017 14.8 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Activator of aromatic catabolism NAGLU_C PF12972.7 CDO71697.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain TFIIA PF03153.13 CDO71698.1 - 0.04 13.9 16.7 0.05 13.6 16.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 CDO71698.1 - 0.048 13.8 36.5 0.082 13.1 36.5 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated cIII PF08134.11 CDO71698.1 - 1.2 9.0 3.9 2.8 7.8 3.9 1.7 1 0 0 1 1 1 0 cIII protein family Nbl1_Borealin_N PF10444.9 CDO71699.1 - 1.5e-14 53.3 0.6 2.9e-14 52.4 0.6 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Borealin PF10512.9 CDO71699.1 - 0.0064 16.5 0.9 0.0064 16.5 0.9 2.9 3 1 1 4 4 4 2 Cell division cycle-associated protein 8 RasGEF PF00617.19 CDO71700.1 - 2.7e-47 161.3 0.0 4.7e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CDO71700.1 - 1.7e-19 70.0 0.0 4.7e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF2239 PF09998.9 CDO71700.1 - 0.034 13.9 0.3 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) SH3_2 PF07653.17 CDO71701.1 - 1.2e-13 50.5 0.0 1.9e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CDO71701.1 - 2.1e-13 49.9 0.0 3.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDO71701.1 - 1e-12 47.4 0.0 1.7e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain NicO PF03824.16 CDO71702.1 - 2.5e-21 76.3 2.2 7.2e-20 71.5 0.0 2.7 2 1 0 2 2 2 1 High-affinity nickel-transport protein PMP1_2 PF08114.11 CDO71702.1 - 0.21 11.4 3.0 1.3 8.9 0.2 2.9 2 0 0 2 2 2 0 ATPase proteolipid family Phage_holin_2_4 PF16082.5 CDO71702.1 - 0.31 10.8 10.7 0.35 10.6 1.8 2.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like TRI5 PF06330.11 CDO71703.1 - 2.6e-09 36.4 0.0 3.3e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Cyclin_N PF00134.23 CDO71704.1 - 3.4e-10 39.7 0.0 1.2e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ribosomal_S7 PF00177.21 CDO71704.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e PIG-U PF06728.13 CDO71705.1 - 2e-99 333.2 20.9 2.3e-99 333.1 20.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U p450 PF00067.22 CDO71706.1 - 1.6e-61 208.5 0.0 3.9e-47 161.0 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 TRI5 PF06330.11 CDO71707.1 - 1.6e-09 37.1 0.2 2.4e-06 26.7 0.0 3.1 3 0 0 3 3 3 3 Trichodiene synthase (TRI5) EspB PF05802.11 CDO71707.1 - 0.0042 17.1 0.0 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 Enterobacterial EspB protein TRI5 PF06330.11 CDO71708.1 - 9.4e-05 21.4 0.6 0.0016 17.4 0.2 2.6 2 1 0 2 2 2 1 Trichodiene synthase (TRI5) TRI5 PF06330.11 CDO71709.1 - 0.00047 19.1 0.0 0.00056 18.9 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) SeqA_N PF17206.3 CDO71709.1 - 0.14 11.5 0.0 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 SeqA protein N-terminal domain Mito_carr PF00153.27 CDO71710.1 - 3.9e-35 119.7 6.4 2.5e-13 49.7 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein NCA2 PF08637.10 CDO71712.1 - 4.6e-87 291.9 0.0 7.7e-87 291.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Glyco_hydro_61 PF03443.14 CDO71712.1 - 3.8e-46 157.6 0.0 6.5e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 CDO71713.1 - 6.7e-64 215.6 0.1 9.2e-64 215.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 CDO71713.1 - 1.1e-12 47.7 7.6 2.6e-12 46.5 7.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Mod_r PF07200.13 CDO71714.1 - 2.4e-44 151.0 1.1 2.9e-44 150.7 1.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.6 CDO71714.1 - 0.0055 16.8 3.7 0.012 15.6 3.7 1.5 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF349 PF03993.12 CDO71714.1 - 0.0091 16.3 0.3 0.14 12.5 0.3 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF349) DUF4337 PF14235.6 CDO71714.1 - 0.099 12.8 0.6 0.15 12.2 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Tropomyosin_1 PF12718.7 CDO71714.1 - 0.12 12.6 2.7 0.71 10.0 1.2 2.1 1 1 1 2 2 2 0 Tropomyosin like NuA4 PF09340.10 CDO71715.1 - 1.3e-25 89.1 0.1 1.3e-25 89.1 0.1 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 AAA PF00004.29 CDO71716.1 - 3e-40 137.7 0.0 5.5e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CDO71716.1 - 4.9e-20 71.2 0.2 9.2e-20 70.4 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CDO71716.1 - 2.2e-11 43.4 0.1 5.1e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDO71716.1 - 0.00047 20.6 0.2 0.063 13.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CDO71716.1 - 0.0016 18.6 0.1 0.015 15.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CDO71716.1 - 0.002 18.1 0.2 0.016 15.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDO71716.1 - 0.0026 17.5 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDO71716.1 - 0.0071 16.6 0.5 0.42 10.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 CDO71716.1 - 0.0096 15.4 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 CDO71716.1 - 0.0096 15.7 0.2 0.57 9.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CDO71716.1 - 0.021 14.2 0.1 0.065 12.6 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CDO71716.1 - 0.034 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDO71716.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CDO71716.1 - 0.18 11.5 0.2 0.51 10.0 0.1 1.9 2 1 0 2 2 2 0 AAA domain XhlA PF10779.9 CDO71716.1 - 2.6 8.3 6.1 26 5.1 4.5 2.3 2 0 0 2 2 2 0 Haemolysin XhlA 2-oxoacid_dh PF00198.23 CDO71717.1 - 1.3e-50 172.1 0.0 3.8e-50 170.5 0.0 1.7 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDO71717.1 - 8.1e-18 64.0 0.0 1.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CDO71717.1 - 1.8e-14 53.8 0.1 4.2e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CDO71717.1 - 3e-06 27.0 0.5 6.3e-06 25.9 0.5 1.5 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_3 PF13437.6 CDO71717.1 - 0.00046 20.9 0.0 0.0012 19.5 0.0 1.7 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_D23 PF16576.5 CDO71717.1 - 0.0029 16.9 0.0 0.0052 16.0 0.0 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Fucokinase PF07959.12 CDO71717.1 - 0.053 12.5 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase DUF21 PF01595.20 CDO71718.1 - 3.6e-25 88.7 1.1 2.4e-24 86.0 1.1 2.0 1 1 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CDO71718.1 - 0.0031 17.9 0.3 0.82 10.2 0.0 2.7 2 1 0 2 2 2 2 CBS domain tRNA_U5-meth_tr PF05958.11 CDO71719.1 - 1.8e-14 53.5 0.0 6.3e-14 51.7 0.0 1.9 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 CDO71719.1 - 6e-08 32.4 0.0 9.7e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 CDO71719.1 - 3.9e-07 30.7 0.0 8.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO71719.1 - 2e-05 24.4 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO71719.1 - 0.00012 22.7 0.0 0.00026 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDO71719.1 - 0.00047 19.8 0.0 0.00098 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 CDO71719.1 - 0.0017 18.0 0.0 0.028 14.1 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 CDO71719.1 - 0.0034 18.1 0.0 0.0089 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDO71719.1 - 0.0042 16.5 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 CDO71719.1 - 0.024 14.3 0.0 0.26 11.0 0.0 2.3 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 CDO71719.1 - 0.025 14.4 0.0 0.077 12.8 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 CDO71719.1 - 0.05 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RsmJ PF04378.13 CDO71719.1 - 0.064 12.5 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal RNA large subunit methyltransferase D, RlmJ PS_Dcarbxylase PF02666.15 CDO71720.1 - 2.1e-73 246.2 0.0 2.5e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DHC_N1 PF08385.12 CDO71721.1 - 5.3e-113 378.6 7.2 4.8e-67 226.9 0.9 3.3 2 1 1 3 3 3 3 Dynein heavy chain, N-terminal region 1 Pro_3_hydrox_C PF05373.11 CDO71721.1 - 0.04 14.0 0.1 1.5 8.9 0.1 2.8 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal FAA_hydro_N_2 PF18288.1 CDO71721.1 - 0.056 13.9 0.4 21 5.6 0.0 3.5 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Gly_radical PF01228.21 CDO71721.1 - 0.069 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 Glycine radical Pkinase PF00069.25 CDO71722.1 - 2e-58 197.8 0.0 6.6e-58 196.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71722.1 - 6.2e-27 94.5 0.1 4.4e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDO71722.1 - 0.00032 20.1 0.1 0.0063 15.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDO71722.1 - 0.00074 19.5 0.3 0.089 12.7 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDO71722.1 - 0.0024 17.3 0.6 0.0092 15.3 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDO71722.1 - 0.096 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CDO71722.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Med21 PF11221.8 CDO71723.1 - 6.2e-18 65.4 2.0 8e-18 65.1 2.0 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex PEP-utilisers_N PF05524.13 CDO71723.1 - 0.0028 17.8 0.7 0.0042 17.2 0.7 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal GAT PF03127.14 CDO71723.1 - 0.0062 16.8 0.4 0.013 15.8 0.1 1.6 2 0 0 2 2 2 1 GAT domain Com_YlbF PF06133.11 CDO71723.1 - 0.039 14.5 2.5 0.069 13.8 2.5 1.4 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DUF2203 PF09969.9 CDO71723.1 - 0.11 13.2 0.3 0.14 12.9 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Rtf2 PF04641.12 CDO71724.1 - 2.5e-76 256.5 0.2 3e-76 256.2 0.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 CDO71724.1 - 0.0017 18.5 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 CDO71724.1 - 0.0026 17.5 0.1 0.043 13.6 0.0 2.5 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Thrombin_light PF09396.10 CDO71724.1 - 0.086 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Thrombin light chain RsmJ PF04378.13 CDO71724.1 - 0.094 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ MRP-S31 PF15433.6 CDO71724.1 - 0.4 10.3 4.8 0.072 12.8 1.3 1.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 HNH_2 PF13391.6 CDO71725.1 - 0.00041 20.4 0.1 0.0011 19.0 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.16 CDO71726.1 - 5.2e-11 42.1 27.4 2.3e-10 39.9 27.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 CDO71726.1 - 1.1e-05 25.2 2.0 3.6e-05 23.5 2.0 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 gag_pre-integrs PF13976.6 CDO71726.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 GAG-pre-integrase domain TB2_DP1_HVA22 PF03134.19 CDO71727.1 - 3.1e-28 97.5 5.2 4.9e-28 96.9 5.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ost5 PF05251.12 CDO71728.1 - 6.2e-21 74.4 10.0 7.4e-21 74.2 10.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 TFIIS_C PF01096.18 CDO71729.1 - 2.5e-17 62.4 9.8 2.8e-17 62.3 1.6 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CDO71729.1 - 2.1e-08 33.9 5.5 1e-06 28.5 0.3 3.1 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 CDO71729.1 - 3.8e-05 23.8 2.5 0.058 13.6 0.0 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain DZR PF12773.7 CDO71729.1 - 5.6e-05 23.1 7.8 0.0021 18.1 0.2 2.7 2 1 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.6 CDO71729.1 - 0.00067 19.0 10.8 0.88 9.1 0.2 4.1 4 0 0 4 4 4 2 zinc-ribbon domain zf-NADH-PPase PF09297.11 CDO71729.1 - 0.0007 19.2 8.8 0.0043 16.7 2.8 2.8 2 1 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Baculo_LEF5_C PF11792.8 CDO71729.1 - 0.0021 17.7 0.8 0.0021 17.7 0.8 2.5 2 2 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.7 CDO71729.1 - 0.0025 17.8 7.1 0.022 14.8 0.5 2.9 2 1 1 3 3 3 1 Transposase zinc-ribbon domain UPF0547 PF10571.9 CDO71729.1 - 0.004 17.2 9.4 0.81 9.8 0.6 3.5 3 0 0 3 3 3 2 Uncharacterised protein family UPF0547 zf-RING_7 PF02591.15 CDO71729.1 - 0.0043 17.2 6.6 1.8 8.8 0.0 3.7 4 0 0 4 4 3 1 C4-type zinc ribbon domain Mu-like_Com PF10122.9 CDO71729.1 - 0.0079 15.6 4.2 0.42 10.1 0.0 2.9 2 1 1 3 3 3 1 Mu-like prophage protein Com TF_Zn_Ribbon PF08271.12 CDO71729.1 - 0.0094 15.4 3.2 0.0094 15.4 3.2 3.3 2 2 0 2 2 2 1 TFIIB zinc-binding DUF523 PF04463.12 CDO71729.1 - 0.02 14.9 0.2 0.024 14.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF523) Nudix_N_2 PF14803.6 CDO71729.1 - 0.026 14.4 3.1 0.026 14.4 3.1 3.2 2 2 0 2 2 2 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.11 CDO71729.1 - 0.03 14.2 6.1 0.99 9.4 0.1 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 CDO71729.1 - 0.039 13.6 10.1 6.7 6.4 0.0 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_2 PF13240.6 CDO71729.1 - 0.04 13.6 13.6 1.4 8.8 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain PHD PF00628.29 CDO71729.1 - 0.042 13.7 8.1 0.47 10.4 0.5 2.8 2 1 1 3 3 3 0 PHD-finger zf-FPG_IleRS PF06827.14 CDO71729.1 - 0.051 13.4 3.3 5.5 6.9 0.3 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DUF3268 PF11672.8 CDO71729.1 - 0.076 13.3 0.8 0.076 13.3 0.8 2.6 2 1 1 3 3 3 0 zinc-finger-containing domain Rubredoxin_2 PF18073.1 CDO71729.1 - 0.08 12.7 12.3 2 8.2 0.1 4.0 4 0 0 4 4 4 0 Rubredoxin metal binding domain DUF2387 PF09526.10 CDO71729.1 - 0.083 13.1 7.4 3.6 7.8 1.0 2.8 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) DNA_ligase_ZBD PF03119.16 CDO71729.1 - 0.087 12.9 4.9 3.1 7.9 0.4 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Lar_restr_allev PF14354.6 CDO71729.1 - 0.095 13.1 7.5 1.7 9.1 0.8 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar HypA PF01155.19 CDO71729.1 - 0.096 12.7 6.9 0.44 10.6 0.3 2.3 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 CDO71729.1 - 0.1 12.8 13.3 2.4 8.4 0.1 4.0 3 1 0 4 4 4 0 Zinc ribbon domain zf-tcix PF14952.6 CDO71729.1 - 0.16 11.6 3.9 5.2 6.8 0.0 3.0 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding DNA_RNApol_7kD PF03604.13 CDO71729.1 - 0.22 11.3 7.6 7.5 6.3 1.2 3.5 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_9 PF14369.6 CDO71729.1 - 0.22 11.8 5.7 22 5.4 0.0 3.7 3 1 1 4 4 4 0 zinc-ribbon Zn_ribbon_SprT PF17283.2 CDO71729.1 - 0.3 11.0 3.3 23 5.0 0.1 3.3 3 1 0 3 3 3 0 SprT-like zinc ribbon domain Terminase_GpA PF05876.12 CDO71729.1 - 0.34 9.4 4.6 2.9 6.3 0.9 2.3 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) Zn_ribbon_recom PF13408.6 CDO71729.1 - 0.39 11.3 5.4 17 6.0 0.1 3.3 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain CpXC PF14353.6 CDO71729.1 - 0.52 10.4 10.0 10 6.2 1.7 3.5 1 1 1 3 3 3 0 CpXC protein Ogr_Delta PF04606.12 CDO71729.1 - 0.64 10.0 6.5 1.6 8.8 0.5 3.1 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger DUF3797 PF12677.7 CDO71729.1 - 0.79 9.7 0.1 0.79 9.7 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) zinc_ribbon_4 PF13717.6 CDO71729.1 - 0.88 9.5 10.3 5.8 6.9 1.0 3.9 3 1 0 3 3 3 0 zinc-ribbon domain Methyltransf_13 PF08421.11 CDO71729.1 - 0.98 9.7 6.5 14 6.0 0.1 3.4 3 1 0 3 3 3 0 Putative zinc binding domain A2L_zn_ribbon PF08792.10 CDO71729.1 - 1 9.2 13.2 1.6 8.6 0.1 3.8 4 0 0 4 4 4 0 A2L zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 CDO71729.1 - 2.1 8.4 12.9 13 5.9 0.0 3.6 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Auto_anti-p27 PF06677.12 CDO71729.1 - 2.1 8.6 6.9 3.9 7.7 0.5 3.2 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_13 PF09855.9 CDO71729.1 - 2.5 8.3 11.9 1.6 9.0 0.1 3.3 3 1 1 4 4 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF35_N PF12172.8 CDO71729.1 - 3.3 7.7 8.0 19 5.3 0.1 3.7 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Rpr2 PF04032.16 CDO71729.1 - 4.5 7.6 7.6 88 3.5 7.6 2.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_S27e PF01667.17 CDO71729.1 - 5.9 6.7 10.3 18 5.2 2.2 3.3 3 1 1 4 4 4 0 Ribosomal protein S27 XAF1_C PF18608.1 CDO71729.1 - 7.7 6.2 9.3 3.4 7.3 1.6 3.2 3 1 1 4 4 4 0 XIAP-associated factor 1 C-terminal domain zf-IS66 PF13005.7 CDO71729.1 - 9.5 6.7 16.1 4.3 7.8 0.2 3.6 3 1 1 4 4 3 0 zinc-finger binding domain of transposase IS66 Peptidase_M1 PF01433.20 CDO71730.1 - 1e-37 129.8 0.0 1.4e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M61 PF05299.12 CDO71730.1 - 0.061 13.7 3.1 2 8.8 3.1 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Het-C PF07217.11 CDO71731.1 - 0.027 13.0 0.3 0.034 12.7 0.3 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Effector_1 PF04518.12 CDO71731.1 - 0.036 13.2 0.3 0.049 12.7 0.3 1.3 1 0 0 1 1 1 0 Effector from type III secretion system DUF4559 PF15112.6 CDO71731.1 - 0.14 11.8 2.6 0.16 11.6 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Hrs_helical PF12210.8 CDO71731.1 - 0.67 10.5 6.7 0.23 12.0 2.2 2.3 1 1 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Seryl_tRNA_N PF02403.22 CDO71731.1 - 1.1 9.5 7.0 0.26 11.5 2.0 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ERM PF00769.19 CDO71731.1 - 1.2 8.9 12.7 0.32 10.8 5.7 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ZapB PF06005.12 CDO71731.1 - 1.2 9.6 11.3 0.48 10.9 0.3 3.3 4 0 0 4 4 4 0 Cell division protein ZapB FUSC PF04632.12 CDO71731.1 - 2.8 6.3 7.0 4 5.8 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family GET2 PF08690.10 CDO71732.1 - 1.1e-10 41.8 0.0 3.9e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 GET complex subunit GET2 L51_S25_CI-B8 PF05047.16 CDO71733.1 - 3.2e-10 39.8 0.1 6.2e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain YL1 PF05764.13 CDO71734.1 - 3.7e-31 109.1 20.2 4.6e-31 108.8 20.2 1.1 1 0 0 1 1 1 1 YL1 nuclear protein RAP80_UIM PF18282.1 CDO71734.1 - 2.1 8.2 11.1 2.4 8.0 1.6 2.4 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif APH PF01636.23 CDO71735.1 - 1.2e-11 45.0 0.1 1.4e-10 41.6 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF282 PF03380.14 CDO71735.1 - 0.017 15.1 1.1 0.042 13.8 0.1 2.1 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 MutS_V PF00488.21 CDO71736.1 - 7.5e-54 182.6 0.5 5.3e-51 173.3 0.4 2.3 1 1 0 2 2 2 2 MutS domain V MutS_III PF05192.18 CDO71736.1 - 2.8e-23 83.1 4.8 2.9e-23 83.1 0.7 2.8 2 2 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CDO71736.1 - 6.5e-05 23.2 0.1 0.00019 21.7 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV AAA_14 PF13173.6 CDO71736.1 - 0.08 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DAO PF01266.24 CDO71737.1 - 9.6e-15 55.0 0.7 3.1e-14 53.3 0.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDO71737.1 - 0.00042 19.6 0.1 0.00085 18.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 CDO71737.1 - 0.0017 17.7 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO71737.1 - 0.0095 16.1 0.1 0.019 15.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDO71737.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 CDO71737.1 - 0.049 13.6 0.3 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 CDO71737.1 - 0.18 10.9 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) BCIP PF13862.6 CDO71738.1 - 6.3e-64 215.5 0.0 7.9e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Vps35 PF03635.17 CDO71739.1 - 0 1016.1 0.0 0 1015.9 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Tsi6 PF18660.1 CDO71739.1 - 7.7 6.6 6.1 62 3.7 0.1 3.9 4 0 0 4 4 4 0 Tsi6 RNA_pol_Rpb1_1 PF04997.12 CDO71740.1 - 1.8e-106 356.0 0.0 2.8e-106 355.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CDO71740.1 - 2.7e-103 345.0 0.0 4.4e-103 344.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CDO71740.1 - 1.9e-74 249.4 0.0 3.6e-74 248.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CDO71740.1 - 2.6e-67 226.4 0.0 4.6e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 CDO71740.1 - 1.1e-48 165.2 0.0 3.6e-48 163.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 CDO71740.1 - 2.3e-48 163.6 0.7 5e-48 162.5 0.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 CDO71740.1 - 1.1e-35 121.9 0.0 2.2e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CDO71740.1 - 1.9e-06 27.9 112.6 0.028 14.8 2.7 9.7 7 2 1 8 8 8 5 RNA polymerase Rpb1 C-terminal repeat Herpes_BLLF1 PF05109.13 CDO71740.1 - 1.7 6.5 24.5 2.7 5.9 24.5 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) VHS PF00790.19 CDO71741.1 - 6.9e-46 155.6 0.5 1.3e-44 151.4 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 CDO71741.1 - 1.1e-18 67.1 6.9 1.8e-18 66.5 6.9 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CDO71741.1 - 6.9e-06 26.3 4.8 1.3e-05 25.3 4.8 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger UIM PF02809.20 CDO71741.1 - 5.8e-05 22.7 15.3 0.0028 17.5 2.8 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 CDO71741.1 - 0.00029 21.1 0.5 0.0011 19.3 0.1 2.2 2 0 0 2 2 2 1 GAT domain zf-RING_2 PF13639.6 CDO71741.1 - 0.64 10.4 9.7 0.23 11.8 6.9 1.7 2 0 0 2 2 2 0 Ring finger domain zf-B_box PF00643.24 CDO71741.1 - 4.4 7.6 9.5 0.77 10.0 5.2 1.9 2 0 0 2 2 2 0 B-box zinc finger Amidase PF01425.21 CDO71742.1 - 1.3e-96 324.3 0.0 1.5e-96 324.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 CDO71744.1 - 3e-104 349.5 0.0 4.1e-102 342.4 0.0 2.0 1 1 0 1 1 1 1 Amidase PDZ_5 PF17817.1 CDO71745.1 - 0.087 13.1 0.1 0.83 10.0 0.0 2.6 2 0 0 2 2 2 0 PDZ domain Sirohm_synth_M PF14824.6 CDO71745.1 - 0.73 9.3 5.8 8.6 5.9 0.0 2.8 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Pro_dh PF01619.18 CDO71746.1 - 1.9e-48 165.5 0.0 4.1e-27 95.5 0.0 2.2 2 0 0 2 2 2 2 Proline dehydrogenase Resolvase PF00239.21 CDO71746.1 - 0.0078 16.3 1.0 0.2 11.8 0.0 2.7 3 0 0 3 3 3 1 Resolvase, N terminal domain Pro_dh PF01619.18 CDO71747.1 - 5.6e-37 127.9 0.0 3.2e-21 76.1 0.0 2.4 2 1 0 2 2 2 2 Proline dehydrogenase TIP120 PF08623.10 CDO71748.1 - 4.7e-60 202.2 1.7 9.4e-57 191.4 0.0 3.8 4 0 0 4 4 4 2 TATA-binding protein interacting (TIP20) HEAT PF02985.22 CDO71748.1 - 1.6e-21 74.5 20.7 0.11 12.8 0.0 14.8 15 1 0 15 15 15 5 HEAT repeat HEAT_2 PF13646.6 CDO71748.1 - 9.2e-15 54.8 14.3 0.021 15.2 0.0 8.8 9 1 1 10 10 8 5 HEAT repeats Adaptin_N PF01602.20 CDO71748.1 - 5.8e-13 48.3 5.4 0.0012 17.5 0.0 4.8 3 2 1 4 4 4 3 Adaptin N terminal region Cnd1 PF12717.7 CDO71748.1 - 5.5e-11 42.8 3.5 0.0068 16.5 0.0 7.1 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDO71748.1 - 9.7e-11 41.9 18.2 0.76 10.4 0.0 11.4 13 0 0 13 13 12 3 HEAT-like repeat CLASP_N PF12348.8 CDO71748.1 - 3.7e-10 39.8 6.8 1.5e-06 28.0 0.0 6.0 5 1 0 6 6 6 1 CLASP N terminal UME PF08064.13 CDO71748.1 - 1.4e-07 31.3 1.2 1.1 9.2 0.0 5.9 5 1 0 5 5 5 2 UME (NUC010) domain MMS19_N PF14500.6 CDO71748.1 - 2.7e-07 30.4 2.7 0.031 13.9 0.0 5.5 5 2 0 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II Vac14_Fab1_bd PF12755.7 CDO71748.1 - 3.5e-05 24.3 1.7 3 8.5 0.2 6.6 7 2 2 9 9 8 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 CDO71748.1 - 0.00019 21.6 6.9 0.18 12.0 0.1 5.6 4 2 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Telomere_reg-2 PF10193.9 CDO71748.1 - 0.00048 20.6 5.0 0.32 11.4 0.0 4.0 3 1 1 4 4 4 2 Telomere length regulation protein V-ATPase_H_C PF11698.8 CDO71748.1 - 0.012 15.7 2.9 4.4 7.4 0.1 5.4 6 0 0 6 6 6 0 V-ATPase subunit H MMS19_C PF12460.8 CDO71748.1 - 0.04 13.0 30.9 0.75 8.8 2.5 6.0 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal RNA_pol_3_Rpc31 PF11705.8 CDO71748.1 - 0.041 14.1 2.8 0.079 13.2 2.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 API5 PF05918.11 CDO71748.1 - 0.054 12.3 1.8 7.1 5.3 0.3 3.3 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) ParcG PF10274.9 CDO71748.1 - 0.06 13.5 5.9 62 3.6 0.0 5.7 6 0 0 6 6 6 0 Parkin co-regulated protein Tti2 PF10521.9 CDO71748.1 - 0.15 11.5 9.1 5.5 6.4 0.0 5.1 4 2 1 5 5 5 0 Tti2 family Sec5 PF15469.6 CDO71748.1 - 0.29 10.9 3.3 0.4 10.5 0.2 2.5 3 0 0 3 3 3 0 Exocyst complex component Sec5 NOA36 PF06524.12 CDO71748.1 - 4.5 6.5 9.6 7.3 5.8 9.6 1.2 1 0 0 1 1 1 0 NOA36 protein AAA PF00004.29 CDO71750.1 - 1.2e-36 126.1 0.0 1.9e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CDO71750.1 - 1e-27 95.9 0.2 4.5e-27 93.8 0.3 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CDO71750.1 - 2.8e-24 85.0 8.3 2.8e-24 85.0 8.3 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CDO71750.1 - 7.5e-08 32.1 0.0 3.3e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_14 PF13173.6 CDO71750.1 - 0.0066 16.5 0.6 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Use1 PF09753.9 CDO71750.1 - 0.056 13.2 2.9 0.099 12.4 2.9 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 AAA_22 PF13401.6 CDO71750.1 - 0.063 13.6 2.5 2.1 8.6 0.6 2.8 2 1 0 2 2 2 0 AAA domain TPR_2 PF07719.17 CDO71750.1 - 1.1 9.5 5.2 5.9 7.3 2.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 CDO71751.1 - 3.5e-53 180.6 0.0 4.6e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71751.1 - 1e-22 80.7 0.0 1.4e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO71751.1 - 3.6e-05 23.2 0.2 0.00015 21.2 0.2 1.9 1 1 0 1 1 1 1 Kinase-like Ribosomal_L19e PF01280.20 CDO71752.1 - 3.5e-62 208.7 10.3 3.5e-62 208.7 10.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.25 CDO71752.1 - 0.012 15.3 0.0 0.065 13.0 0.0 2.3 2 0 0 2 2 2 0 S4 domain FAF PF11250.8 CDO71752.1 - 0.11 12.7 1.6 0.16 12.2 0.1 2.0 2 0 0 2 2 2 0 Fantastic Four meristem regulator MOZ_SAS PF01853.18 CDO71753.1 - 1.8e-63 213.5 0.0 8.8e-63 211.2 0.0 1.9 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 CDO71753.1 - 7.1e-18 64.0 3.5 7.2e-09 35.1 0.2 2.7 2 0 0 2 2 2 2 MYST family zinc finger domain Tudor-knot PF11717.8 CDO71753.1 - 4.4e-07 29.7 0.4 1.1e-06 28.4 0.4 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CDO71753.1 - 0.0016 18.8 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Agenet PF05641.12 CDO71753.1 - 0.0031 18.0 0.1 0.008 16.6 0.1 1.7 1 0 0 1 1 1 1 Agenet domain Acetyltransf_1 PF00583.25 CDO71753.1 - 0.0036 17.5 0.0 0.0075 16.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pkinase PF00069.25 CDO71755.1 - 3.9e-31 108.4 0.0 5e-23 81.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71755.1 - 1.2e-15 57.5 0.0 6.4e-15 55.1 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO71755.1 - 0.00063 19.1 0.0 0.00097 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YjhX_toxin PF09857.9 CDO71755.1 - 0.19 11.7 0.1 0.59 10.1 0.1 1.8 1 1 0 1 1 1 0 Putative toxin of bacterial toxin-antitoxin pair F-box-like PF12937.7 CDO71756.1 - 4e-08 33.0 0.3 7.4e-08 32.2 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO71756.1 - 1.2e-06 28.3 0.1 1.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 F-box domain DUF1631 PF07793.11 CDO71756.1 - 4.4 5.6 5.3 1.3 7.3 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) SAP30_Sin3_bdg PF13867.6 CDO71757.1 - 1.3e-07 31.8 0.3 8.2e-05 22.9 0.3 2.3 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Sel1 PF08238.12 CDO71758.1 - 2.5e-16 59.8 7.4 6.7e-05 23.4 0.2 3.8 4 0 0 4 4 4 3 Sel1 repeat TPR_2 PF07719.17 CDO71758.1 - 0.89 9.8 5.5 0.67 10.2 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PBP PF01161.20 CDO71759.1 - 2.3e-14 53.8 0.2 5.7e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein NAM-associated PF14303.6 CDO71759.1 - 0.037 14.8 1.1 0.08 13.7 1.1 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DDE_3 PF13358.6 CDO71760.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Peptidase_S28 PF05577.12 CDO71761.1 - 1.8e-49 168.7 0.0 4.8e-49 167.3 0.0 1.6 1 1 1 2 2 2 1 Serine carboxypeptidase S28 DNA_topoisoIV PF00521.20 CDO71762.1 - 5.4e-131 437.4 0.2 1.3e-130 436.2 0.2 1.7 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CDO71762.1 - 1.2e-50 171.1 0.7 1.2e-50 171.1 0.7 2.5 2 1 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CDO71762.1 - 7.5e-29 100.4 0.4 1.8e-28 99.2 0.4 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CDO71762.1 - 2.6e-13 50.5 0.4 7.2e-13 49.0 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CDO71762.1 - 4.3e-08 33.3 0.0 1.4e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 Toprim domain EF-G-binding_N PF07299.11 CDO71762.1 - 0.05 14.1 0.1 8.5 7.0 0.1 3.2 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal CTU2 PF10288.9 CDO71763.1 - 0.016 15.4 0.1 0.019 15.2 0.1 1.1 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 LSM PF01423.22 CDO71764.1 - 1.7e-07 30.8 0.0 2.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDO71764.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain UPF0052 PF01933.18 CDO71765.1 - 2.8e-29 102.3 0.0 3.5e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Chorismate_synt PF01264.21 CDO71766.1 - 8.7e-70 235.0 0.0 1e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF3817 PF12823.7 CDO71767.1 - 0.029 15.2 0.5 0.068 14.0 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) bZIP_1 PF00170.21 CDO71768.1 - 1.4e-12 47.5 14.4 2.5e-12 46.7 14.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 CDO71768.1 - 0.0012 18.5 2.3 0.0029 17.3 2.3 1.6 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.15 CDO71768.1 - 0.0052 16.8 14.2 0.0052 16.8 14.2 2.4 1 1 1 2 2 2 1 Basic region leucine zipper SHE3 PF17078.5 CDO71768.1 - 0.0063 16.3 8.1 0.0099 15.6 8.1 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 GvpL_GvpF PF06386.11 CDO71768.1 - 0.2 11.6 3.1 0.3 11.0 3.1 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TSC22 PF01166.18 CDO71768.1 - 0.25 11.7 4.8 2 8.8 3.9 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family DBR1 PF05011.13 CDO71768.1 - 0.27 11.6 4.3 0.87 10.0 4.3 1.9 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Glutaredoxin2_C PF04399.13 CDO71768.1 - 0.29 11.0 2.2 0.96 9.3 1.8 2.0 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain Pox_G5 PF04599.12 CDO71768.1 - 1.6 7.6 4.1 2.2 7.2 4.1 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein rRNA_processing PF08524.11 CDO71768.1 - 2 8.4 16.0 4.2 7.4 16.0 1.5 1 0 0 1 1 1 0 rRNA processing bZIP_Maf PF03131.17 CDO71768.1 - 2.4 8.7 15.1 0.52 10.9 11.2 1.9 2 0 0 2 2 1 0 bZIP Maf transcription factor YabA PF06156.13 CDO71768.1 - 2.7 8.7 6.3 0.44 11.2 2.1 1.8 2 0 0 2 2 2 0 Initiation control protein YabA Tmemb_cc2 PF10267.9 CDO71768.1 - 6.3 5.8 17.3 0.026 13.7 8.1 1.5 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein HeH PF12949.7 CDO71770.1 - 0.031 14.0 0.0 0.089 12.5 0.0 1.8 1 0 0 1 1 1 0 HeH/LEM domain Glyco_hydro_88 PF07470.13 CDO71771.1 - 1.1e-05 24.7 1.3 0.00023 20.4 1.0 2.2 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 CAP_N PF01213.19 CDO71771.1 - 0.97 8.9 4.2 0.39 10.2 1.1 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TetR_C_28 PF17937.1 CDO71771.1 - 6 7.4 7.3 19 5.8 0.3 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF1708 PF08101.11 CDO71773.1 - 1.3e-21 77.3 0.0 1.3e-17 64.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 CDO71773.1 - 0.05 13.4 0.0 0.33 10.8 0.0 2.2 3 0 0 3 3 3 0 RhoGAP domain Pro_isomerase PF00160.21 CDO71775.1 - 1.2e-40 139.4 0.1 1.4e-40 139.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD OPT PF03169.15 CDO71776.1 - 3e-193 643.8 63.9 3.5e-193 643.6 63.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PS_Dcarbxylase PF02666.15 CDO71777.1 - 1.6e-58 197.6 0.0 2.5e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 CDO71777.1 - 1e-38 131.7 0.1 1.2e-19 70.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_6 PF13405.6 CDO71777.1 - 0.024 14.6 0.0 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain TBPIP PF07106.13 CDO71778.1 - 1.1e-11 44.4 0.0 1.9e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain DUF812 PF05667.11 CDO71778.1 - 0.52 9.1 4.6 0.69 8.7 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Mito_carr PF00153.27 CDO71779.1 - 3.2e-52 174.4 5.9 2.1e-20 72.4 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CDO71779.1 - 0.0024 17.1 0.0 0.031 13.4 0.0 2.3 2 0 0 2 2 2 1 Gammaproteobacterial serine protease F-box-like PF12937.7 CDO71781.1 - 0.00052 19.8 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO71781.1 - 0.0072 16.2 0.0 0.11 12.4 0.0 2.8 3 0 0 3 3 3 1 F-box domain DDE_1 PF03184.19 CDO71784.1 - 7.2e-23 81.1 0.0 1.3e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CDO71784.1 - 3.1e-09 36.7 0.7 2.6e-08 33.8 0.1 2.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 CDO71784.1 - 0.0039 17.0 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1752 PF08550.10 CDO71785.1 - 4.5e-12 45.6 0.5 8.2e-12 44.7 0.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) F-box PF00646.33 CDO71786.1 - 1.3e-07 31.3 2.4 7.4e-05 22.5 0.1 3.1 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 CDO71786.1 - 5.6e-06 26.2 1.0 0.0032 17.3 0.0 3.3 2 0 0 2 2 2 2 F-box-like Fungal_trans PF04082.18 CDO71787.1 - 5e-30 104.4 0.0 7.9e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 CDO71787.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Zn_clus PF00172.18 CDO71787.1 - 0.03 14.4 9.4 0.059 13.5 0.7 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mon1 PF03164.14 CDO71787.1 - 0.16 11.0 0.1 0.3 10.1 0.0 1.4 2 0 0 2 2 2 0 Trafficking protein Mon1 AAA PF00004.29 CDO71789.1 - 7.6e-15 55.5 0.0 1.4e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 CDO71789.1 - 1e-10 41.5 0.0 2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_16 PF13191.6 CDO71789.1 - 4.6e-10 40.1 0.0 1.7e-09 38.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDO71789.1 - 1.5e-06 28.5 0.0 2.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain YL1 PF05764.13 CDO71789.1 - 0.00066 19.9 4.8 0.0012 19.1 4.8 1.3 1 0 0 1 1 1 1 YL1 nuclear protein AAA_19 PF13245.6 CDO71789.1 - 0.0012 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDO71789.1 - 0.0085 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 CDO71789.1 - 0.019 14.7 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CDO71789.1 - 0.021 14.7 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CDO71789.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 CDO71789.1 - 0.049 13.3 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NHase_beta PF02211.15 CDO71789.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Nitrile hydratase beta subunit NTPase_1 PF03266.15 CDO71789.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 CDO71789.1 - 0.14 12.7 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 CDO71789.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain T2SSE PF00437.20 CDO71789.1 - 0.15 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.14 CDO71789.1 - 0.27 10.4 0.0 0.41 9.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase F-box-like PF12937.7 CDO71790.1 - 0.00021 21.1 0.1 0.00052 19.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO71790.1 - 0.033 14.1 0.1 0.09 12.7 0.1 1.8 1 0 0 1 1 1 0 F-box domain CENP-B_dimeris PF09026.10 CDO71791.1 - 0.8 10.1 7.6 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 CDO71791.1 - 1 9.0 3.7 1.4 8.6 0.6 2.3 2 0 0 2 2 2 0 FAM176 family Hairy_orange PF07527.13 CDO71793.1 - 0.082 13.1 0.2 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 Hairy Orange Med3 PF11593.8 CDO71794.1 - 0.014 14.6 2.6 0.014 14.6 2.6 2.0 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal Tir_receptor_N PF07490.11 CDO71794.1 - 0.084 12.7 0.3 0.084 12.7 0.3 1.9 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus DUF423 PF04241.15 CDO71795.1 - 0.91 9.8 5.6 0.23 11.7 0.3 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF423) S10_plectin PF03501.15 CDO71797.1 - 1.4e-37 127.7 0.2 4.1e-34 116.5 0.0 2.1 2 0 0 2 2 2 2 Plectin/S10 domain TrmB PF01978.19 CDO71797.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB LRR_4 PF12799.7 CDO71798.1 - 3.8e-27 93.9 18.6 2.3e-09 37.4 0.8 8.7 8 2 1 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDO71798.1 - 7.5e-23 80.1 15.2 1.3e-13 50.5 3.6 7.2 7 1 0 7 7 7 5 Leucine rich repeat LRR_1 PF00560.33 CDO71798.1 - 1.4e-13 49.4 13.8 4.1 8.3 0.0 10.9 11 0 0 11 11 11 3 Leucine Rich Repeat LRR_6 PF13516.6 CDO71798.1 - 3.4e-13 48.5 23.2 0.48 10.6 0.2 10.9 11 0 0 11 11 11 5 Leucine Rich repeat LRR_9 PF14580.6 CDO71798.1 - 0.062 12.8 1.5 1.1 8.8 0.1 3.1 4 1 0 4 4 4 0 Leucine-rich repeat Glyco_hydro_18 PF00704.28 CDO71799.1 - 2.8e-22 79.8 2.7 9.7e-22 78.1 2.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 CDO71799.1 - 0.0036 17.8 5.3 0.0036 17.8 5.3 3.0 3 0 0 3 3 3 1 Carbohydrate binding domain MSA-2c PF12238.8 CDO71799.1 - 0.32 11.0 2.5 0.52 10.3 2.5 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Glyco_hydro_18 PF00704.28 CDO71800.1 - 5.9e-23 82.1 4.7 1.7e-22 80.6 4.7 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Oxidored_molyb PF00174.19 CDO71801.1 - 3.3e-58 196.1 0.0 5.2e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CDO71801.1 - 4.3e-16 59.2 1.2 8.8e-16 58.2 1.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Serinc PF03348.15 CDO71802.1 - 7.9e-163 542.4 13.2 9e-163 542.2 13.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) OppC_N PF12911.7 CDO71802.1 - 0.31 11.0 14.5 0.86 9.6 0.1 4.3 3 1 1 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C DUF2214 PF09980.9 CDO71802.1 - 0.39 10.5 6.4 0.093 12.5 0.3 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2214) Rad51 PF08423.11 CDO71803.1 - 1.4e-11 44.2 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CDO71803.1 - 1.2e-07 31.5 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CDO71803.1 - 2.2e-07 30.5 0.0 3.6e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 KaiC RecA PF00154.21 CDO71803.1 - 0.0018 17.8 0.0 0.0073 15.8 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA PF00004.29 CDO71803.1 - 0.0021 18.5 0.0 0.0076 16.7 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDO71803.1 - 0.027 14.9 0.3 0.066 13.6 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain DnaB_C PF03796.15 CDO71803.1 - 0.038 13.3 0.0 0.13 11.5 0.0 1.8 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain NACHT PF05729.12 CDO71803.1 - 0.057 13.3 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 CDO71803.1 - 0.059 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain CobU PF02283.16 CDO71803.1 - 0.079 12.5 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_22 PF13401.6 CDO71803.1 - 0.087 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDO71803.1 - 0.095 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin GerPB PF10803.8 CDO71803.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Spore germination GerPB Terminase_6 PF03237.15 CDO71803.1 - 0.16 11.6 0.0 0.46 10.1 0.0 1.7 2 0 0 2 2 2 0 Terminase-like family AAA_24 PF13479.6 CDO71803.1 - 0.19 11.4 0.0 0.58 9.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Glyco_transf_22 PF03901.17 CDO71804.1 - 3.5e-34 118.7 15.2 4.3e-34 118.5 15.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CoxIIa PF08113.11 CDO71804.1 - 0.043 13.6 1.3 0.043 13.6 1.3 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family Phage_holin_2_1 PF04971.12 CDO71804.1 - 0.6 10.2 2.4 1.2 9.2 0.1 2.6 3 0 0 3 3 3 0 Bacteriophage P21 holin S MFS_1 PF07690.16 CDO71805.1 - 1.2e-27 96.8 19.4 1.2e-27 96.8 19.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CDO71805.1 - 0.00018 21.0 1.0 0.00018 21.0 1.0 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TMEM61 PF15105.6 CDO71805.1 - 0.14 11.9 0.4 0.24 11.2 0.4 1.3 1 0 0 1 1 1 0 TMEM61 protein family DIOX_N PF14226.6 CDO71806.1 - 5.7e-20 72.2 0.0 4.3e-19 69.4 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO71806.1 - 1.2e-11 45.0 0.0 2.2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.18 CDO71807.1 - 7.1e-11 42.0 10.7 1.8e-10 40.7 10.7 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CDO71807.1 - 0.0095 16.2 5.1 0.022 15.1 5.1 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf_C2H2_13 PF18508.1 CDO71807.1 - 3.1 7.5 7.9 0.39 10.3 0.8 2.8 2 1 1 3 3 3 0 Zinc finger domain IDO PF01231.18 CDO71808.1 - 4.3e-134 447.6 0.0 2.6e-133 445.0 0.0 1.8 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase TFIIF_beta PF02270.15 CDO71809.1 - 6.4e-26 90.3 0.4 1.1e-25 89.5 0.4 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 CDO71809.1 - 2.5e-17 63.8 0.1 1.3e-15 58.2 0.0 2.5 2 1 0 2 2 2 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 CDO71809.1 - 8.6e-05 23.4 0.4 0.00017 22.4 0.3 1.6 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Glyco_hydro_18 PF00704.28 CDO71811.1 - 1.2e-22 81.1 2.5 5.1e-22 79.0 2.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Cytochrom_C PF00034.21 CDO71812.1 - 2e-11 44.9 0.2 2.9e-11 44.3 0.2 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CDO71812.1 - 4.8e-08 33.2 2.6 5.5e-07 29.8 2.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CDO71812.1 - 0.0081 15.9 0.0 0.075 12.7 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.14 CDO71812.1 - 0.042 14.5 0.0 0.045 14.4 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase MIS13 PF08202.11 CDO71813.1 - 5e-23 81.8 4.7 5e-23 81.8 4.7 2.4 2 1 0 2 2 2 1 Mis12-Mtw1 protein family Uso1_p115_C PF04871.13 CDO71813.1 - 2 8.8 9.3 8 6.9 6.8 2.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region GMC_oxred_N PF00732.19 CDO71815.1 - 5.7e-57 193.3 0.0 1.3e-56 192.1 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO71815.1 - 1.9e-36 125.7 0.0 3.3e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CDO71815.1 - 8.3e-06 25.1 0.2 1.3e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 CDO71815.1 - 4.1e-05 23.7 0.2 0.0001 22.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDO71815.1 - 0.00013 21.2 0.0 0.00032 19.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CDO71815.1 - 0.00035 20.3 0.3 0.00065 19.4 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDO71815.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO71815.1 - 0.016 14.4 0.0 0.038 13.2 0.0 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 CDO71815.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Acetyltransf_1 PF00583.25 CDO71816.1 - 5.2e-14 52.5 0.8 6.3e-14 52.2 0.1 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO71816.1 - 4.4e-08 33.4 3.1 4.5e-08 33.4 0.1 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDO71816.1 - 9.1e-08 32.1 0.1 1.6e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDO71816.1 - 2.1e-07 30.8 0.0 3.8e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 CDO71816.1 - 0.00012 22.3 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDO71816.1 - 0.00024 21.2 0.5 0.00037 20.6 0.5 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Aldose_epim PF01263.20 CDO71819.1 - 1.1e-14 54.4 0.0 1.2e-07 31.4 0.0 2.7 2 1 0 2 2 2 2 Aldose 1-epimerase ADH_zinc_N PF00107.26 CDO71820.1 - 1.3e-16 60.8 0.0 2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO71820.1 - 4.5e-05 24.5 0.0 6.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO71820.1 - 0.0005 19.9 0.0 0.00077 19.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CDO71820.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 CDO71821.1 - 6.3e-15 55.3 0.1 1.9e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO71821.1 - 2.9e-09 36.8 0.0 4.8e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDO71821.1 - 1.2e-05 26.4 0.0 2.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CDO71822.1 - 8.8e-13 48.4 0.1 2.2e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO71822.1 - 4.2e-09 36.2 0.0 7.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDO71822.1 - 2.9e-05 25.1 0.0 5.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 CDO71823.1 - 9.6e-12 45.2 0.1 1.6e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CDO71823.1 - 2.6e-08 33.7 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CDO71823.1 - 2.6e-07 30.3 0.1 0.0084 15.6 0.0 3.4 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CDO71823.1 - 1.7e-05 25.2 0.0 3.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CDO71823.1 - 0.00043 20.4 0.0 0.00087 19.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CDO71823.1 - 0.00054 20.5 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 CDO71823.1 - 0.0007 18.8 0.0 0.0014 17.8 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 CDO71823.1 - 0.047 12.7 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family XFP_N PF09364.10 CDO71824.1 - 2.1e-151 503.9 0.0 2.7e-151 503.5 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 CDO71824.1 - 1.9e-78 262.6 0.0 3.4e-78 261.8 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 CDO71824.1 - 9.7e-77 256.6 0.0 1.4e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 CDO71824.1 - 0.014 15.2 0.1 0.041 13.7 0.1 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain IcmF-related PF06761.12 CDO71824.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing Acetate_kinase PF00871.17 CDO71825.1 - 3.4e-91 305.9 0.1 7.8e-91 304.7 0.1 1.6 1 1 0 1 1 1 1 Acetokinase family Abhydrolase_1 PF00561.20 CDO71826.1 - 1.6e-14 54.1 0.4 5.1e-14 52.5 0.2 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO71826.1 - 4.2e-10 40.6 1.5 1.4e-09 38.9 1.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO71826.1 - 1.8e-09 37.2 0.0 4.3e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CDO71826.1 - 0.0085 15.9 0.0 0.55 10.0 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Cpn60_TCP1 PF00118.24 CDO71827.1 - 4.6e-158 526.9 1.2 5.2e-158 526.7 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fra10Ac1 PF09725.9 CDO71828.1 - 2.2e-49 166.7 0.3 3.1e-49 166.2 0.3 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Glyco_hydro_11 PF00457.17 CDO71828.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 zf-C4_Topoisom PF01396.19 CDO71828.1 - 0.21 11.4 1.5 0.47 10.3 1.5 1.5 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger FAM176 PF14851.6 CDO71828.1 - 3.2 7.4 6.4 2.3 7.9 4.0 2.1 2 1 0 2 2 2 0 FAM176 family Methyltransf_28 PF02636.17 CDO71829.1 - 2.7e-48 164.9 0.0 3.5e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase eIF-6 PF01912.18 CDO71830.1 - 4.1e-83 277.6 0.1 5.7e-83 277.2 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family PTPlike_phytase PF14566.6 CDO71831.1 - 9.3e-111 366.9 0.0 1.4e-47 161.7 0.0 3.7 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 CDO71831.1 - 0.00059 19.6 0.0 0.083 12.7 0.0 3.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Translin PF01997.16 CDO71831.1 - 0.0061 16.6 1.8 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 Translin family Y_phosphatase PF00102.27 CDO71831.1 - 0.015 14.9 0.0 0.67 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein-tyrosine phosphatase CDKN3 PF05706.12 CDO71831.1 - 0.028 14.1 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Mid2 PF04478.12 CDO71832.1 - 0.081 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF647 PF04884.14 CDO71835.1 - 4.5e-43 147.6 1.7 5.8e-43 147.3 1.7 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF1729 PF08354.10 CDO71836.1 - 5.9e-150 499.0 0.0 1e-149 498.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_I_H PF18314.1 CDO71836.1 - 7.5e-76 254.3 0.3 1.9e-75 253.0 0.3 1.8 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Acyl_transf_1 PF00698.21 CDO71836.1 - 7.2e-73 245.9 1.8 2.2e-71 241.0 0.0 3.7 5 0 0 5 5 5 1 Acyl transferase domain Fas_alpha_ACP PF18325.1 CDO71836.1 - 1.7e-72 243.0 0.0 3.4e-72 242.1 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_meander PF17951.1 CDO71836.1 - 2.2e-47 160.6 0.0 4.7e-47 159.5 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 CDO71836.1 - 2.4e-36 125.7 0.1 1.6e-35 123.0 0.0 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 CDO71836.1 - 2e-28 98.4 0.2 9.9e-28 96.2 0.0 2.3 2 0 0 2 2 2 1 MaoC like domain ketoacyl-synt PF00109.26 CDO71836.1 - 1.4e-26 93.6 0.3 3.1e-26 92.5 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_N PF17828.1 CDO71836.1 - 2.2e-25 89.2 1.7 4.6e-25 88.1 1.7 1.6 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Ketoacyl-synt_C PF02801.22 CDO71836.1 - 2.5e-15 56.5 0.0 6.5e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 CDO71836.1 - 3e-14 53.1 0.0 7.8e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.6 CDO71836.1 - 1.3e-12 47.9 0.0 6.7e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 CDO71836.1 - 2.2e-07 30.5 0.0 6.1e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO71836.1 - 0.00028 20.5 0.0 0.0038 16.8 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO71836.1 - 0.051 13.5 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 KR domain Thiolase_N PF00108.23 CDO71836.1 - 0.087 12.2 0.0 0.25 10.7 0.0 1.7 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF3597 PF12200.8 CDO71836.1 - 0.6 10.6 3.1 2.1 8.9 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) CTP_transf_like PF01467.26 CDO71837.1 - 0.0067 16.6 0.1 2.9 8.1 0.0 3.2 3 1 0 3 3 3 2 Cytidylyltransferase-like DEC-1_N PF04625.13 CDO71838.1 - 0.047 12.7 2.7 0.053 12.5 2.7 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DEAD PF00270.29 CDO71839.1 - 3.3e-28 98.6 0.2 7.1e-28 97.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO71839.1 - 1.1e-23 83.7 0.1 4e-23 81.9 0.1 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDO71839.1 - 0.035 14.4 0.2 0.22 11.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.6 CDO71839.1 - 0.05 12.9 0.1 0.099 12.0 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF202 PF02656.15 CDO71841.1 - 0.0023 18.3 4.1 0.08 13.4 0.9 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF202) DnaJ_C PF01556.18 CDO71842.1 - 3.4e-41 140.8 0.4 4.6e-41 140.4 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDO71842.1 - 1.8e-28 98.4 1.7 2.8e-28 97.8 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 CDO71842.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein Kelch_4 PF13418.6 CDO71843.1 - 1.4e-23 82.6 7.0 1.5e-08 34.5 0.1 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CDO71843.1 - 1.3e-19 70.0 15.8 0.0001 22.5 0.2 7.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CDO71843.1 - 7.1e-19 67.4 2.2 0.0014 18.6 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 CDO71843.1 - 4.6e-13 48.5 0.2 0.00016 21.2 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CDO71843.1 - 5.2e-13 48.4 0.6 0.0068 16.3 0.1 5.1 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 CDO71843.1 - 1.8e-12 47.1 8.0 4.9e-06 26.6 0.2 4.9 3 1 1 4 4 4 2 Kelch motif Transposase_21 PF02992.14 CDO71844.1 - 1e-23 83.7 0.0 2.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 CDO71844.1 - 3.1e-05 23.6 0.0 7.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) HBS1_N PF08938.10 CDO71844.1 - 7.1 7.0 7.8 24 5.3 7.8 1.9 1 1 0 1 1 1 0 HBS1 N-terminus DivIC PF04977.15 CDO71845.1 - 0.024 14.4 3.4 0.024 14.4 3.4 2.4 3 0 0 3 3 3 0 Septum formation initiator ACBP PF00887.19 CDO71846.1 - 3.2e-31 107.4 0.4 3.2e-31 107.4 0.4 1.3 2 0 0 2 2 2 1 Acyl CoA binding protein DUF4886 PF16227.5 CDO71846.1 - 0.0028 16.9 0.4 0.0036 16.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4886) PH PF00169.29 CDO71847.1 - 6.5e-26 90.9 0.2 2.5e-19 69.7 0.3 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 CDO71847.1 - 4.2e-11 43.2 4.4 2.1e-06 28.1 5.7 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 CDO71847.1 - 5.4e-09 36.1 0.2 2.3e-06 27.6 0.4 2.8 2 1 0 2 2 2 1 PH domain PH_8 PF15409.6 CDO71847.1 - 2.6e-06 27.6 0.4 5.5e-06 26.6 0.3 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 CDO71847.1 - 5.6e-05 23.0 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 CDO71847.1 - 0.00023 21.5 0.5 0.049 14.0 0.9 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.7 CDO71847.1 - 0.0042 17.2 1.7 4.1 7.5 1.7 2.8 2 1 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_2 PF08458.10 CDO71847.1 - 0.012 15.9 0.0 5.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_17 PF18012.1 CDO71847.1 - 0.036 13.8 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 PH domain PH_4 PF15404.6 CDO71847.1 - 0.14 11.9 0.0 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Zn_clus PF00172.18 CDO71848.1 - 2.1e-05 24.6 7.2 3.5e-05 23.8 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CDO71849.1 - 2.2e-47 161.7 0.0 3.2e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 CDO71850.1 - 2.7e-34 118.6 0.0 4.9e-34 117.8 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DnaJ_C PF01556.18 CDO71851.1 - 3.4e-22 79.1 0.0 9.3e-19 68.0 0.0 2.2 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.31 CDO71851.1 - 6.2e-14 51.9 0.8 6.2e-14 51.9 0.8 1.8 2 0 0 2 2 2 1 DnaJ domain Herpes_UL25 PF01499.16 CDO71851.1 - 0.012 14.2 1.9 0.022 13.3 1.9 1.5 1 0 0 1 1 1 0 Herpesvirus UL25 family Zip PF02535.22 CDO71851.1 - 0.85 8.8 5.4 1.3 8.2 5.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CDO71851.1 - 9.1 4.9 6.7 14 4.4 6.7 1.2 1 0 0 1 1 1 0 Presenilin NAD_binding_10 PF13460.6 CDO71852.1 - 6.1e-07 29.5 0.2 1e-06 28.8 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CDO71852.1 - 0.00019 21.0 0.2 0.011 15.2 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CDO71852.1 - 0.00067 19.3 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Rnk_N PF14760.6 CDO71852.1 - 0.11 13.0 1.3 0.27 11.7 1.3 1.7 1 0 0 1 1 1 0 Rnk N-terminus NAD_binding_10 PF13460.6 CDO71853.1 - 0.019 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding AP3D1 PF06375.11 CDO71853.1 - 0.48 10.6 7.2 1 9.6 7.2 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DDE_3 PF13358.6 CDO71854.1 - 3.2e-34 117.8 0.0 4.2e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 CDO71854.1 - 0.012 15.8 0.0 0.05 13.8 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain Fungal_trans PF04082.18 CDO71855.1 - 3.2e-13 49.3 0.0 6.8e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CDO71855.1 - 1.9e-07 31.1 16.4 3.3e-07 30.3 16.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlxA PF14282.6 CDO71855.1 - 0.015 15.2 0.1 0.015 15.2 0.1 1.8 2 0 0 2 2 2 0 FlxA-like protein HTH_47 PF16221.5 CDO71855.1 - 0.12 11.9 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 winged helix-turn-helix ADK PF00406.22 CDO71856.1 - 9.3e-58 194.6 0.0 1.2e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CDO71856.1 - 4.2e-21 75.8 0.1 9.1e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CDO71856.1 - 9.8e-18 63.8 0.0 1.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CDO71856.1 - 0.00079 20.0 0.0 0.0087 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDO71856.1 - 0.0097 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RILP PF11461.8 CDO71856.1 - 0.11 12.8 0.1 0.32 11.3 0.1 1.9 1 0 0 1 1 1 0 Rab interacting lysosomal protein RsgA_GTPase PF03193.16 CDO71856.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Cerato-platanin PF07249.12 CDO71857.1 - 4.8e-54 181.5 3.1 5.5e-54 181.3 3.1 1.0 1 0 0 1 1 1 1 Cerato-platanin DDOST_48kD PF03345.14 CDO71858.1 - 3.7e-134 447.7 0.0 4.4e-134 447.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DDE_1 PF03184.19 CDO71859.1 - 6e-17 61.8 0.0 9.4e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CDO71859.1 - 0.00044 20.2 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 CDO71859.1 - 0.0013 18.4 0.1 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.6 CDO71859.1 - 0.0015 18.3 0.4 0.0055 16.5 0.1 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease NmrA PF05368.13 CDO71860.1 - 1.5e-20 73.8 0.0 1.9e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CDO71860.1 - 1.7e-11 44.3 0.2 3.3e-11 43.4 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CDO71860.1 - 5.5e-08 33.3 0.0 1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CDO71860.1 - 4.8e-06 26.9 0.0 6.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 CDO71860.1 - 0.0003 20.9 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 CDO71860.1 - 0.00092 20.0 0.0 0.0017 19.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.21 CDO71860.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family OCD_Mu_crystall PF02423.15 CDO71860.1 - 0.02 13.8 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 CDO71860.1 - 0.055 14.1 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Terpene_synth_C PF03936.16 CDO71861.1 - 4.7e-06 26.2 0.0 6.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.22 CDO71862.1 - 7.2e-70 236.0 0.0 8.2e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 CDO71863.1 - 1.7e-19 70.3 0.6 2.7e-19 69.7 0.6 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CDO71863.1 - 2.7e-09 37.2 1.8 3.9e-09 36.7 1.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CDO71863.1 - 3.1e-06 27.6 0.5 1.6e-05 25.4 0.1 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CDO71863.1 - 0.00012 22.3 0.1 0.00029 21.1 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CDO71863.1 - 0.00048 19.7 0.1 0.0019 17.7 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 CDO71863.1 - 0.00088 19.4 0.5 0.002 18.2 0.1 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Glu_dehyd_C PF16912.5 CDO71863.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DXP_reductoisom PF02670.16 CDO71863.1 - 0.057 14.1 0.1 0.12 13.1 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.19 CDO71863.1 - 0.072 12.1 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family EutN_CcmL PF03319.13 CDO71863.1 - 0.086 13.4 0.1 0.23 12.1 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome ABC2_membrane PF01061.24 CDO71864.1 - 2.1e-38 131.9 15.8 2.1e-38 131.9 15.8 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CDO71864.1 - 1.8e-25 90.0 0.0 5.2e-25 88.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 CDO71864.1 - 3.4e-06 26.4 22.0 1.5e-05 24.3 22.3 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 CDO71864.1 - 0.00042 20.2 0.3 0.12 12.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CDO71864.1 - 0.0017 18.3 0.2 0.0032 17.4 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CDO71864.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CDO71864.1 - 0.012 15.5 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 CDO71864.1 - 0.013 15.2 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 CDO71864.1 - 0.017 15.7 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDO71864.1 - 0.019 15.3 0.2 0.05 13.9 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDO71864.1 - 0.02 14.5 0.1 0.16 11.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDO71864.1 - 0.024 14.9 0.1 0.053 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDO71864.1 - 0.026 14.2 0.2 0.051 13.3 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDO71864.1 - 0.03 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 CDO71864.1 - 0.032 14.4 0.3 0.065 13.4 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CDO71864.1 - 0.039 14.5 0.3 0.093 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CDO71864.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 CDO71864.1 - 0.078 13.4 0.1 0.28 11.6 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CDO71864.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 CDO71864.1 - 0.19 11.8 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 CDO71864.1 - 0.23 11.4 0.6 0.64 9.9 0.6 1.7 2 0 0 2 2 2 0 NTPase HsbA PF12296.8 CDO71865.1 - 1.3e-07 32.1 4.0 1.3e-07 32.1 4.0 2.3 2 1 0 2 2 2 1 Hydrophobic surface binding protein A C166 PF17615.2 CDO71865.1 - 5e-07 30.0 5.0 1.2e-06 28.7 5.0 1.7 1 1 0 1 1 1 1 Family of unknown function HsbA PF12296.8 CDO71866.1 - 1.6e-07 31.7 5.4 1.6e-07 31.7 5.4 2.0 2 1 0 2 2 2 1 Hydrophobic surface binding protein A C166 PF17615.2 CDO71866.1 - 1.5e-05 25.2 5.0 3e-05 24.2 5.0 1.7 1 1 0 1 1 1 1 Family of unknown function Baculo_PEP_C PF04513.12 CDO71866.1 - 0.0047 17.0 4.1 0.53 10.3 0.7 2.7 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus PSI_PsaJ PF01701.18 CDO71866.1 - 0.025 15.1 2.0 0.025 15.1 2.0 1.9 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IX / PsaJ Pkinase PF00069.25 CDO71868.1 - 3.4e-46 157.7 0.0 1.6e-44 152.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71868.1 - 6.8e-26 91.1 0.0 4.4e-25 88.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CDO71868.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDO71868.1 - 0.0021 17.4 0.0 0.022 14.1 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 CDO71868.1 - 0.05 13.5 2.6 0.19 11.6 0.3 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family DOPA_dioxygen PF08883.11 CDO71870.1 - 1.4e-20 73.5 0.0 2.2e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Pribosyltran_N PF13793.6 CDO71871.1 - 3.5e-49 165.6 0.3 1.1e-47 160.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CDO71871.1 - 1.8e-41 142.2 1.1 9.6e-37 126.8 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CDO71871.1 - 6.9e-18 64.7 0.1 4.1e-17 62.2 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CDO71871.1 - 9.2e-05 22.0 0.1 0.00016 21.2 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AA_kinase PF00696.28 CDO71872.1 - 5e-38 131.0 2.3 6.6e-38 130.7 2.3 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 CDO71872.1 - 7.7e-11 41.8 0.0 0.00024 21.0 0.1 2.6 2 0 0 2 2 2 2 PUA domain Pex14_N PF04695.13 CDO71872.1 - 1.5 9.5 5.5 23 5.6 1.8 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HIT PF01230.23 CDO71873.1 - 1.4e-09 38.5 0.3 1.8e-09 38.2 0.3 1.2 1 0 0 1 1 1 1 HIT domain Per1 PF04080.13 CDO71874.1 - 2.8e-90 302.5 11.0 3.2e-90 302.4 11.0 1.0 1 0 0 1 1 1 1 Per1-like family DUF2516 PF10724.9 CDO71874.1 - 1.1 9.6 5.0 0.68 10.3 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2516) Hist_deacetyl PF00850.19 CDO71875.1 - 3.5e-81 273.0 0.1 4.3e-81 272.7 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MgtE PF01769.16 CDO71876.1 - 8.1e-29 100.5 28.4 1.3e-20 74.0 10.2 3.9 3 1 1 4 4 4 3 Divalent cation transporter DUF1129 PF06570.11 CDO71876.1 - 0.022 14.3 0.1 0.022 14.3 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Phage_holin_3_3 PF16083.5 CDO71876.1 - 1.2 9.3 8.5 0.35 11.0 2.0 3.2 2 1 1 3 3 3 0 LydA holin phage, holin superfamily III Ada3 PF10198.9 CDO71877.1 - 3.1e-26 92.1 0.3 3.1e-26 92.1 0.3 2.2 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Mu-like_Pro PF10123.9 CDO71877.1 - 2.2 7.8 8.0 0.19 11.2 0.7 2.1 2 0 0 2 2 2 0 Mu-like prophage I protein Herpes_UL25 PF01499.16 CDO71877.1 - 2.5 6.5 4.1 0.87 8.0 0.3 1.9 2 0 0 2 2 2 0 Herpesvirus UL25 family RNA_polI_A34 PF08208.11 CDO71878.1 - 2.9e-26 92.8 3.6 2.9e-26 92.8 3.6 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 DUF1691 PF07950.11 CDO71879.1 - 2e-06 28.5 1.8 4.8e-06 27.2 1.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1691) UCR_6-4kD PF08997.10 CDO71879.1 - 8.2 6.4 8.1 14 5.7 0.0 3.1 3 1 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein HMG_box PF00505.19 CDO71880.1 - 3.4e-13 49.8 0.6 6.4e-13 48.9 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO71880.1 - 8.4e-05 23.1 0.4 0.00017 22.1 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain COX4 PF02936.14 CDO71880.1 - 0.082 12.9 0.4 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Trp_oprn_chp PF09534.10 CDO71881.1 - 0.07 12.9 0.1 0.13 12.0 0.1 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RSN1_TM PF13967.6 CDO71881.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport ADH_N PF08240.12 CDO71882.1 - 9e-29 99.5 2.9 1.7e-28 98.7 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO71882.1 - 6.2e-17 61.8 0.0 1.1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO71882.1 - 4.1e-07 31.1 0.0 7.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CDO71882.1 - 3e-05 23.4 0.0 4.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CDO71882.1 - 0.00012 21.5 0.4 0.00021 20.7 0.4 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CDO71882.1 - 0.011 15.9 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 CDO71882.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF983 PF06170.12 CDO71882.1 - 0.34 11.4 1.3 0.89 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) E1-E2_ATPase PF00122.20 CDO71883.1 - 2.3e-47 160.9 2.0 2.3e-47 160.9 2.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDO71883.1 - 5.1e-24 85.0 13.1 3.6e-18 65.9 1.2 3.8 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CDO71883.1 - 5.3e-20 71.3 0.0 1.4e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDO71883.1 - 9.2e-18 65.3 0.1 1.4e-15 58.2 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDO71883.1 - 3.9e-15 55.3 0.0 1.1e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDO71883.1 - 0.00034 20.4 0.5 0.033 13.9 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cerato-platanin PF07249.12 CDO71884.1 - 1.1e-15 57.8 0.1 1.6e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Cerato-platanin CBM_21 PF03370.13 CDO71885.1 - 5.1e-28 97.5 0.0 8.6e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CDO71885.1 - 4.7e-08 33.5 0.3 8.9e-08 32.6 0.3 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Glyoxalase_3 PF13468.6 CDO71886.1 - 2.2e-29 102.8 0.3 6.6e-29 101.3 0.2 1.7 1 1 1 2 2 2 2 Glyoxalase-like domain IBR PF01485.21 CDO71887.1 - 4.4e-16 58.8 17.6 1.8e-10 40.9 9.1 3.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 CDO71887.1 - 0.0022 17.8 6.5 0.0022 17.8 6.5 5.3 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO71887.1 - 0.0026 17.6 5.0 0.0026 17.6 5.0 4.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 CDO71888.1 - 7.1e-43 143.8 19.8 1.6e-07 31.9 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO71888.1 - 8.9e-22 77.2 0.1 5.6e-06 26.6 0.1 6.1 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO71888.1 - 1.2e-07 31.0 0.7 0.13 11.2 0.1 4.1 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDO71888.1 - 1.5e-07 31.5 0.2 0.0011 18.9 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 CDO71888.1 - 0.0003 20.0 0.0 0.00043 19.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Nucleoporin_N PF08801.11 CDO71888.1 - 0.0016 17.2 0.0 1.3 7.7 0.0 3.4 1 1 3 4 4 4 1 Nup133 N terminal like IKI3 PF04762.12 CDO71888.1 - 0.039 12.0 0.0 0.061 11.3 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Nbas_N PF15492.6 CDO71888.1 - 0.042 13.2 0.6 9.1 5.5 0.0 3.4 2 2 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Det1 PF09737.9 CDO71888.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Glycos_transf_1 PF00534.20 CDO71889.1 - 4.3e-21 75.2 0.0 3.5e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDO71889.1 - 1.1e-10 42.0 0.0 2.2e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CDO71889.1 - 6.4e-06 26.5 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 TerB PF05099.13 CDO71889.1 - 0.073 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TerB OPT PF03169.15 CDO71891.1 - 6.9e-140 467.6 41.8 3.8e-125 418.9 38.9 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Calcipressin PF04847.12 CDO71892.1 - 1.8e-32 112.6 0.0 2.6e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.22 CDO71892.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ccdc124 PF06244.12 CDO71893.1 - 2e-29 102.7 10.2 2e-29 102.7 10.2 2.0 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Sugarporin_N PF11471.8 CDO71894.1 - 0.034 14.1 0.8 0.097 12.6 0.0 2.2 2 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Cerato-platanin PF07249.12 CDO71896.1 - 3.5e-46 156.2 2.0 4.1e-46 156.0 2.0 1.0 1 0 0 1 1 1 1 Cerato-platanin PaaA_PaaC PF05138.12 CDO71898.1 - 0.2 10.8 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein VSP PF03302.13 CDO71899.1 - 2.7e-05 23.2 23.4 2.7e-05 23.2 23.4 4.6 2 1 3 5 5 5 2 Giardia variant-specific surface protein DUF4381 PF14316.6 CDO71899.1 - 0.038 14.2 3.8 0.071 13.4 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3382 PF11862.8 CDO71899.1 - 0.078 13.3 0.3 0.14 12.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Methyltransf_23 PF13489.6 CDO71901.1 - 4.8e-19 68.8 0.0 7e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO71901.1 - 6.7e-17 62.0 0.0 2e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO71901.1 - 1.3e-15 57.8 0.0 5.5e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO71901.1 - 4.6e-15 55.7 0.0 6.4e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO71901.1 - 1.4e-11 45.0 0.0 3e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDO71901.1 - 1.1e-09 37.9 0.0 2.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 CDO71901.1 - 6.9e-07 28.9 0.0 9.7e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CDO71901.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 CDO71901.1 - 0.0028 16.7 0.0 0.006 15.6 0.0 1.5 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase PCMT PF01135.19 CDO71901.1 - 0.016 14.9 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 CDO71901.1 - 0.021 14.5 0.0 0.048 13.3 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 CDO71901.1 - 0.045 13.8 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 CDO71901.1 - 0.052 14.6 0.0 0.14 13.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CDO71902.1 - 2e-16 60.3 0.0 2.5e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO71902.1 - 1.1e-15 58.1 0.0 2.2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO71902.1 - 2.8e-15 56.4 0.0 3.8e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO71902.1 - 6.7e-15 55.5 0.0 1.3e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO71902.1 - 3e-12 47.1 0.0 5.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDO71902.1 - 6e-06 25.9 0.0 9.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CDO71902.1 - 1.8e-05 24.3 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 CDO71902.1 - 3e-05 23.5 0.0 3.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.16 CDO71902.1 - 0.0047 16.1 0.0 0.019 14.1 0.0 1.7 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_8 PF05148.15 CDO71902.1 - 0.0077 16.1 0.0 0.0096 15.8 0.0 1.3 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 CDO71902.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 CDO71902.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW tRNA_U5-meth_tr PF05958.11 CDO71902.1 - 0.026 13.5 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NodS PF05401.11 CDO71902.1 - 0.034 13.8 0.0 0.085 12.5 0.0 1.6 1 1 0 1 1 1 0 Nodulation protein S (NodS) TPMT PF05724.11 CDO71902.1 - 0.087 12.5 0.2 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_24 PF13578.6 CDO71902.1 - 0.095 13.7 0.1 0.28 12.2 0.0 1.8 3 0 0 3 3 1 0 Methyltransferase domain CmcI PF04989.12 CDO71902.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase NNMT_PNMT_TEMT PF01234.17 CDO71902.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family BRCT_2 PF16589.5 CDO71903.1 - 0.00032 21.1 0.0 0.00072 19.9 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Nop14 PF04147.12 CDO71903.1 - 0.094 10.9 20.6 0.13 10.5 20.6 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 CDO71903.1 - 0.89 7.6 24.3 1.2 7.1 24.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 CDO71903.1 - 1.5 8.7 23.7 2.8 7.8 23.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4820 PF16091.5 CDO71903.1 - 1.9 7.8 7.1 4.4 6.6 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Zip PF02535.22 CDO71903.1 - 2.9 7.0 4.3 4.8 6.3 4.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 CDO71903.1 - 5.3 5.7 8.6 8.8 5.0 8.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.16 CDO71903.1 - 9.8 5.6 8.5 18 4.7 8.5 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Ras PF00071.22 CDO71904.1 - 3.4e-62 208.8 0.6 3.9e-62 208.6 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO71904.1 - 8.4e-35 119.6 1.0 8.9e-35 119.5 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO71904.1 - 3.5e-16 59.2 0.1 4.4e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDO71904.1 - 4.9e-05 22.8 0.1 6.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDO71904.1 - 9.3e-05 22.1 0.5 0.00028 20.5 0.5 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDO71904.1 - 0.0002 21.4 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDO71904.1 - 0.00041 20.3 0.4 0.17 11.7 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CDO71904.1 - 0.00067 19.1 0.1 0.0012 18.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 CDO71904.1 - 0.0014 19.1 0.1 0.073 13.5 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 CDO71904.1 - 0.0018 17.8 0.0 0.0085 15.6 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 CDO71904.1 - 0.0028 18.0 0.0 0.0062 16.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain SPATA19 PF15212.6 CDO71904.1 - 0.024 14.8 0.6 0.038 14.2 0.5 1.4 1 1 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial AAA_22 PF13401.6 CDO71904.1 - 0.063 13.6 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDO71904.1 - 0.064 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 CDO71904.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IMS PF00817.20 CDO71905.1 - 1.2e-41 142.2 0.1 2.5e-41 141.1 0.1 1.6 2 0 0 2 2 2 1 impB/mucB/samB family REV1_C PF16727.5 CDO71905.1 - 5.1e-28 97.3 1.7 5.1e-28 97.3 1.7 2.0 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 CDO71905.1 - 3.6e-13 50.3 0.0 1e-12 48.8 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 CDO71905.1 - 1.7e-08 34.8 0.0 3.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 CDO71905.1 - 8.7e-05 22.6 0.0 0.00032 20.9 0.0 2.1 2 0 0 2 2 2 1 IMS family HHH motif UBM PF14377.6 CDO71905.1 - 9.4e-05 21.7 5.5 0.0019 17.6 0.3 3.2 3 0 0 3 3 3 2 Ubiquitin binding region PTCB-BRCT PF12738.7 CDO71905.1 - 0.00047 20.0 0.1 0.0022 17.9 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 CDO71905.1 - 0.0038 17.6 0.1 0.025 15.0 0.1 2.4 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CDO71905.1 - 0.012 15.9 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain DUF1805 PF08827.11 CDO71905.1 - 0.013 15.8 0.0 0.08 13.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) HhH-GPD PF00730.25 CDO71906.1 - 1.5e-21 76.9 0.0 3.1e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CDO71906.1 - 1.2e-08 34.4 0.0 2.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CDO71906.1 - 0.0037 17.8 0.2 1.4 9.6 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 CDO71906.1 - 0.026 14.9 3.4 0.026 14.9 3.4 2.0 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Phos_pyr_kin PF08543.12 CDO71907.1 - 4.2e-52 177.0 0.3 8.2e-51 172.7 0.3 2.2 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CDO71907.1 - 1.9e-41 142.2 0.6 2.5e-41 141.8 0.6 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 CDO71907.1 - 6e-05 22.5 0.7 0.0034 16.7 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Miga PF10265.9 CDO71908.1 - 1.3 7.9 11.9 1.8 7.5 11.9 1.1 1 0 0 1 1 1 0 Mitoguardin DUF5349 PF17298.2 CDO71908.1 - 4.7 6.9 21.3 6.4 6.4 21.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Apt1 PF10351.9 CDO71908.1 - 5.7 5.7 7.0 6.9 5.4 7.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAF-AH_p_II PF03403.13 CDO71911.1 - 1.6e-27 96.0 0.0 2.8e-24 85.4 0.0 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 CDO71911.1 - 0.0026 18.4 0.9 0.0062 17.2 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CDO71911.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 CDO71911.1 - 0.015 14.8 0.0 0.087 12.3 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CDO71911.1 - 0.037 13.3 0.0 0.074 12.3 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CDO71911.1 - 0.076 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 CDO71911.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 CDO71911.1 - 0.18 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Mak10 PF04112.13 CDO71912.1 - 1.3e-50 171.2 0.0 2.9e-50 170.0 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-synt_1b PF00579.25 CDO71913.1 - 5.4e-69 232.7 0.0 1.2e-68 231.6 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) NCD1 PF04904.13 CDO71913.1 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) TFB6 PF17110.5 CDO71914.1 - 8.3e-05 22.4 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH SUV3_C PF12513.8 CDO71915.1 - 1.7e-13 50.3 1.9 1.7e-13 50.3 1.9 2.2 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CDO71915.1 - 8.2e-08 32.6 0.0 1.7e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MRP-S33 PF08293.11 CDO71916.1 - 3.4e-27 94.5 0.2 4.3e-27 94.2 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 EF-hand_4 PF12763.7 CDO71917.1 - 2.3e-17 62.9 0.0 4.2e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 CDO71917.1 - 1.8e-06 28.2 133.3 0.0011 19.3 51.6 4.7 2 1 3 5 5 5 3 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 CDO71917.1 - 8.5e-05 21.8 0.0 0.08 12.5 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDO71917.1 - 0.0031 17.9 0.6 0.013 16.0 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CDO71917.1 - 0.0089 15.9 0.0 2 8.6 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain FAD_binding_7 PF03441.14 CDO71917.1 - 0.032 13.7 0.8 0.36 10.3 0.6 2.3 1 1 1 2 2 2 0 FAD binding domain of DNA photolyase EzrA PF06160.12 CDO71917.1 - 0.054 11.7 5.3 0.087 11.0 5.3 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fez1 PF06818.15 CDO71917.1 - 1.1 9.7 16.7 2.2 8.7 16.7 1.4 1 0 0 1 1 1 0 Fez1 V_ATPase_I PF01496.19 CDO71917.1 - 9.2 4.0 5.5 13 3.5 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RhoGEF PF00621.20 CDO71918.1 - 3.7e-43 147.9 2.8 7.1e-43 147.0 2.8 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 CDO71918.1 - 3.3e-24 84.5 1.2 7.4e-12 44.9 0.2 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CDO71918.1 - 8.4e-24 82.9 0.4 6.2e-13 48.1 0.1 2.5 2 0 0 2 2 2 2 SH3 domain PH_13 PF16652.5 CDO71918.1 - 1.8e-16 60.4 0.0 3.5e-14 52.9 0.0 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.17 CDO71918.1 - 6.4e-13 48.2 0.0 1.4e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.20 CDO71918.1 - 3.6e-10 39.3 0.7 6.9e-10 38.4 0.7 1.5 1 0 0 1 1 1 1 WH2 motif PH PF00169.29 CDO71918.1 - 4.5e-08 33.6 0.0 1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 CDO71918.1 - 0.088 12.7 0.0 0.61 9.9 0.0 2.1 1 1 0 1 1 1 0 PH domain OPA3 PF07047.12 CDO71919.1 - 8.2e-46 154.8 1.3 1.3e-45 154.2 1.3 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) FliD_C PF07195.12 CDO71919.1 - 0.0092 15.4 0.5 0.014 14.8 0.1 1.4 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus COG5 PF10392.9 CDO71919.1 - 0.021 15.0 0.3 0.04 14.1 0.3 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Matrilin_ccoil PF10393.9 CDO71919.1 - 0.038 13.8 0.3 0.12 12.3 0.3 1.8 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin HR1 PF02185.16 CDO71919.1 - 0.038 14.1 0.6 0.11 12.7 0.6 1.8 1 0 0 1 1 1 0 Hr1 repeat Acyl-CoA_ox_N PF14749.6 CDO71919.1 - 0.053 14.1 0.3 0.098 13.2 0.3 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal GLTSCR1 PF15249.6 CDO71919.1 - 0.3 11.6 2.2 2.4 8.7 0.7 2.1 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein IPK PF03770.16 CDO71920.1 - 1.7e-34 119.4 0.0 5e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase CENP-B_dimeris PF09026.10 CDO71920.1 - 0.076 13.4 2.5 0.16 12.4 2.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 CDO71920.1 - 4.2 6.6 5.2 6.4 6.0 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_5_C PF18564.1 CDO71922.1 - 1e-07 32.4 0.1 1.8e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 CDO71922.1 - 2.6e-07 30.4 0.0 0.0012 18.3 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) p450 PF00067.22 CDO71924.1 - 1.6e-59 201.9 0.0 3.8e-59 200.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Apo-CII PF05355.11 CDO71924.1 - 0.05 13.8 0.1 3.3 7.9 0.1 2.6 2 0 0 2 2 2 0 Apolipoprotein C-II DUF655 PF04919.12 CDO71924.1 - 0.062 13.3 0.2 0.15 12.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF655) p450 PF00067.22 CDO71925.1 - 3.2e-47 161.4 0.0 2.7e-36 125.3 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 Lipase_3 PF01764.25 CDO71926.1 - 4.8e-07 29.7 0.0 8.8e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDO71926.1 - 0.022 15.4 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.12 CDO71926.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Rft-1 PF04506.13 CDO71927.1 - 7.8e-147 490.1 8.4 9.8e-147 489.8 8.4 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 CDO71927.1 - 2.1e-11 43.6 7.2 2.1e-11 43.6 7.2 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 CDO71927.1 - 1.8e-07 30.8 8.5 1.8e-07 30.8 8.5 2.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein MFS_1 PF07690.16 CDO71928.1 - 3.1e-25 88.9 17.4 3.1e-25 88.9 17.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily CitMHS PF03600.16 CDO71928.1 - 1.9 7.6 15.4 0.087 12.0 9.5 1.8 2 0 0 2 2 2 0 Citrate transporter DUF5579 PF17742.1 CDO71929.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5579) CDC73_C PF05179.14 CDO71930.1 - 2.6e-52 176.7 0.2 4.2e-52 176.0 0.2 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 CDO71930.1 - 0.11 11.8 0.0 2.4 7.4 0.0 2.4 3 0 0 3 3 3 0 Paf1 complex subunit CDC73 N-terminal eIF2A PF08662.11 CDO71931.1 - 1.3e-16 61.0 0.0 2.4e-13 50.4 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CDO71931.1 - 0.026 14.8 0.0 0.23 11.8 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Hydrophobin PF01185.18 CDO71933.1 - 4.1e-24 85.0 9.0 4.8e-24 84.8 9.0 1.0 1 0 0 1 1 1 1 Fungal hydrophobin CoatB PF10389.9 CDO71933.1 - 0.14 12.0 5.0 0.1 12.4 2.8 1.9 1 1 1 2 2 2 0 Bacteriophage coat protein B FtsX PF02687.21 CDO71934.1 - 0.86 10.1 4.4 0.61 10.6 0.3 2.2 2 1 0 2 2 2 0 FtsX-like permease family Myb_DNA-bind_2 PF08914.11 CDO71935.1 - 1.1e-16 60.7 9.1 6.1e-08 32.7 1.9 2.6 2 0 0 2 2 2 2 Rap1 Myb domain Rap1-DNA-bind PF09197.10 CDO71935.1 - 0.003 18.1 10.9 0.31 11.7 1.7 3.4 1 1 2 3 3 3 2 Rap1, DNA-binding Glyco_hydro_31 PF01055.26 CDO71936.1 - 4.6e-150 500.6 1.6 5.8e-150 500.3 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CDO71936.1 - 1.1e-34 119.1 0.0 2e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 CDO71936.1 - 2.2e-14 53.5 1.2 1e-13 51.4 1.2 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like Shugoshin_C PF07557.11 CDO71939.1 - 1.4e-08 34.4 3.5 1.4e-08 34.4 3.5 2.9 2 0 0 2 2 2 1 Shugoshin C terminus Shugoshin_N PF07558.11 CDO71939.1 - 3.2e-08 33.3 3.2 6.3e-08 32.4 3.2 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF4192 PF13830.6 CDO71939.1 - 0.011 15.8 3.6 0.022 14.8 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Pkinase PF00069.25 CDO71940.1 - 1.9e-49 168.4 0.0 3.7e-49 167.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71940.1 - 3.7e-24 85.4 0.0 9.9e-24 84.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO71940.1 - 0.011 14.6 0.1 0.016 14.0 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CDO71940.1 - 0.041 13.8 2.1 0.067 13.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CDO71940.1 - 0.067 12.2 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CDO71940.1 - 0.073 12.7 0.5 3.8 7.1 0.5 2.3 1 1 0 1 1 1 0 RIO1 family Cyclase PF04199.13 CDO71941.1 - 5.1e-14 52.7 0.0 7e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cyclase PF04199.13 CDO71942.1 - 2.3e-08 34.4 0.0 3.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase MFS_1 PF07690.16 CDO71943.1 - 1.2e-31 109.9 37.2 2.1e-18 66.4 25.4 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF4231 PF14015.6 CDO71943.1 - 0.31 11.5 0.1 0.31 11.5 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) Hydrophobin PF01185.18 CDO71944.1 - 5.2e-24 84.7 8.6 6.5e-24 84.4 8.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Nop14 PF04147.12 CDO71946.1 - 0.027 12.7 2.7 0.036 12.3 2.7 1.0 1 0 0 1 1 1 0 Nop14-like family RSB_motif PF16294.5 CDO71946.1 - 0.12 12.6 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif CDC45 PF02724.14 CDO71946.1 - 1.6 6.9 3.1 2.1 6.6 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CDO71946.1 - 3.3 5.7 12.6 4.1 5.4 12.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 CDO71946.1 - 3.7 7.5 5.2 5.7 6.9 5.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Hydrophobin PF01185.18 CDO71947.1 - 4.5e-21 75.3 8.7 5.5e-21 75.0 8.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Pantoate_transf PF02548.15 CDO71947.1 - 0.1 11.9 0.4 0.11 11.8 0.4 1.1 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Pkinase PF00069.25 CDO71948.1 - 1.2e-29 103.5 0.0 1.5e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO71948.1 - 2.2e-15 56.7 0.0 4.5e-15 55.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO71948.1 - 8.7e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDO71948.1 - 0.00021 21.3 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family AceK PF06315.11 CDO71948.1 - 0.15 10.5 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) RVT_2 PF07727.14 CDO71949.1 - 1.8e-72 243.9 0.0 2.4e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4218 PF13960.6 CDO71949.1 - 0.00054 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.6 CDO71950.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF4419 PF14388.6 CDO71951.1 - 6.6e-62 209.6 0.0 1.3e-47 162.7 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) COesterase PF00135.28 CDO71952.1 - 4.9e-78 263.2 0.1 2.2e-77 261.1 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDO71952.1 - 3.5e-11 43.4 0.1 9.4e-11 42.0 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDO71952.1 - 5.8e-05 22.7 0.5 0.0001 21.9 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_A4 PF01828.17 CDO71952.1 - 0.053 13.0 0.0 1.1 8.7 0.0 2.3 1 1 1 2 2 2 0 Peptidase A4 family p450 PF00067.22 CDO71953.1 - 1.8e-121 406.1 0.0 7e-61 206.4 0.0 2.7 2 2 0 2 2 2 2 Cytochrome P450 Prefoldin_2 PF01920.20 CDO71953.1 - 0.02 14.9 0.5 5.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit Imm39 PF15568.6 CDO71953.1 - 0.12 12.5 0.0 17 5.5 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 39 HTH_16 PF12645.7 CDO71953.1 - 0.16 12.0 0.6 24 5.1 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain WD40 PF00400.32 CDO71955.1 - 6e-06 26.9 0.5 7.3 7.6 0.1 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO71955.1 - 0.00037 20.7 0.0 1.1 9.7 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DDE_3 PF13358.6 CDO71956.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Nucleos_tra2_C PF07662.13 CDO71957.1 - 2.4e-69 233.3 3.4 2.4e-69 233.3 3.4 2.3 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CDO71957.1 - 3e-21 75.8 5.8 3e-21 75.8 5.8 3.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 CDO71957.1 - 0.0096 16.2 7.1 0.0096 16.2 7.1 3.4 3 2 0 3 3 3 1 Nucleoside recognition KCNQC3-Ank-G_bd PF11956.8 CDO71957.1 - 0.16 12.3 0.3 0.95 9.8 0.4 2.1 2 0 0 2 2 2 0 Ankyrin-G binding motif of KCNQ2-3 Ferritin_2 PF13668.6 CDO71959.1 - 2.1e-30 105.7 0.2 3.2e-30 105.1 0.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.24 CDO71960.1 - 1.2e-80 271.6 17.5 6.5e-79 265.9 15.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDO71960.1 - 3.4e-17 62.4 29.9 8.1e-17 61.2 29.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4293 PF14126.6 CDO71960.1 - 1 9.6 4.1 3.2 8.0 4.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF3446 PF11928.8 CDO71963.1 - 0.014 15.6 0.1 0.17 12.2 0.0 2.4 3 0 0 3 3 3 0 Early growth response N-terminal domain Apq12 PF12716.7 CDO71963.1 - 0.017 15.1 1.9 0.017 15.1 1.9 1.9 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis DUF2070 PF09843.9 CDO71963.1 - 0.35 9.1 3.3 0.51 8.6 3.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MPC PF03650.13 CDO71964.1 - 7.2e-41 138.8 0.2 8.6e-41 138.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Na_H_Exchanger PF00999.21 CDO71965.1 - 6.5e-50 170.0 23.4 9e-50 169.5 23.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Phage_holin_8 PF16931.5 CDO71965.1 - 2.1 8.3 5.6 0.39 10.7 0.3 2.4 2 1 0 2 2 2 0 Putative phage holin Acyl-CoA_dh_M PF02770.19 CDO71966.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CDO71966.1 - 0.027 14.7 1.8 0.061 13.5 0.5 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Plavaka PF18759.1 CDO71967.1 - 8.4e-74 248.7 0.0 9.5e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase DUF1382 PF07131.11 CDO71967.1 - 0.11 12.5 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1382) Plavaka PF18759.1 CDO71969.1 - 5.8e-102 341.2 0.1 7.6e-102 340.8 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase DEAD PF00270.29 CDO71971.1 - 2.9e-05 23.9 0.0 6.9e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SecA_DEAD PF07517.14 CDO71971.1 - 0.011 15.1 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain THOC7 PF05615.13 CDO71971.1 - 0.11 12.7 1.9 0.15 12.4 1.9 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 RVT_1 PF00078.27 CDO71973.1 - 2.3e-39 135.2 0.0 4.1e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlxA PF14282.6 CDO71973.1 - 0.075 13.0 1.1 0.17 11.9 1.1 1.5 1 0 0 1 1 1 0 FlxA-like protein UCH_C PF18031.1 CDO71973.1 - 0.087 12.7 0.5 0.22 11.4 0.5 1.7 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases Mitoc_mL59 PF18126.1 CDO71974.1 - 0.019 15.3 4.5 0.025 14.9 4.5 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 DUF5427 PF10310.9 CDO71974.1 - 0.12 11.4 8.5 0.14 11.1 8.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) eIF3_subunit PF08597.10 CDO71974.1 - 3.6 7.4 17.6 5.1 6.9 17.6 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4746 PF15928.5 CDO71974.1 - 3.8 6.9 11.2 4.8 6.5 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Usp PF00582.26 CDO71974.1 - 6.6 7.2 11.1 4.1 7.9 9.4 1.5 2 0 0 2 2 2 0 Universal stress protein family DDRGK PF09756.9 CDO71974.1 - 8.5 5.9 25.4 13 5.3 25.4 1.3 1 0 0 1 1 1 0 DDRGK domain Methyltransf_25 PF13649.6 CDO71976.1 - 2.3e-09 37.8 0.0 5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO71976.1 - 5.7e-08 33.3 0.0 1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO71976.1 - 2.2e-07 31.5 0.0 3.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO71976.1 - 6.9e-07 29.2 0.0 9.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO71976.1 - 0.00011 22.1 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDO71976.1 - 0.00045 19.8 0.0 0.00075 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 CDO71976.1 - 0.0078 17.2 0.0 0.015 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDO71976.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 CDO71976.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CDO71976.1 - 0.19 11.5 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 CDO71978.1 - 2.6e-09 37.7 0.0 5.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO71978.1 - 3.3e-08 34.1 0.0 5.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO71978.1 - 6e-08 33.3 0.0 9.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO71978.1 - 3.9e-06 26.7 0.0 4.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDO71978.1 - 6e-05 22.7 0.0 9.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CDO71978.1 - 0.0018 18.1 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CDO71978.1 - 0.0049 17.9 0.0 0.009 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDO71978.1 - 0.0084 15.5 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF43 PF01861.16 CDO71978.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 CDO71978.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CDO71978.1 - 0.16 11.7 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 CDO71978.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein NodS PF05401.11 CDO71978.1 - 0.21 11.2 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) TMEM239 PF15841.5 CDO71979.1 - 0.33 10.8 4.5 0.44 10.4 4.4 1.4 1 1 0 1 1 1 0 Transmembrane protein 239 family TMEM208_SND2 PF05620.11 CDO71979.1 - 0.79 9.5 3.6 0.68 9.7 2.1 1.6 1 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 TMEM208_SND2 PF05620.11 CDO71980.1 - 5.2 6.8 6.2 15 5.3 6.2 1.8 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Solute_trans_a PF03619.16 CDO71983.1 - 1.7e-63 214.6 13.7 2e-63 214.4 13.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glycos_transf_4 PF00953.21 CDO71983.1 - 0.5 10.3 6.1 0.15 12.0 2.0 1.9 2 1 1 3 3 3 0 Glycosyl transferase family 4 PFL-like PF02901.15 CDO71985.1 - 0.24 10.0 2.3 0.32 9.6 2.3 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like YabA PF06156.13 CDO71985.1 - 3 8.5 4.5 8.1 7.2 3.2 2.2 2 1 1 3 3 3 0 Initiation control protein YabA SET PF00856.28 CDO71986.1 - 1e-09 39.0 0.0 1.9e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 SET domain IBR PF01485.21 CDO71986.1 - 3.6 7.9 7.1 13 6.1 7.1 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF4777 PF16007.5 CDO71987.1 - 0.073 13.3 0.4 0.21 11.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Spc7 PF08317.11 CDO71987.1 - 0.079 11.8 13.2 0.15 10.9 13.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 CDO71987.1 - 0.14 11.5 5.8 0.25 10.7 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 CDO71987.1 - 0.38 10.6 13.3 0.097 12.4 1.5 2.5 2 0 0 2 2 2 0 Septum formation initiator MPS2 PF17060.5 CDO71987.1 - 0.62 9.3 4.8 1.1 8.5 4.8 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 SlyX PF04102.12 CDO71987.1 - 1.7 9.3 10.5 0.53 10.9 0.7 2.8 2 0 0 2 2 2 0 SlyX DUF737 PF05300.11 CDO71988.1 - 0.029 14.7 7.0 0.044 14.1 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF5082 PF16888.5 CDO71988.1 - 0.079 13.2 1.0 0.35 11.1 1.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) HSP70 PF00012.20 CDO71989.1 - 0.27 9.4 0.1 0.76 7.9 0.0 1.7 2 1 0 2 2 2 0 Hsp70 protein HAUS-augmin3 PF14932.6 CDO71990.1 - 0.04 13.5 17.1 0.059 12.9 17.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Jnk-SapK_ap_N PF09744.9 CDO71990.1 - 0.045 14.0 25.0 1.2 9.4 23.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Hemagglutinin PF00509.18 CDO71990.1 - 0.051 12.0 0.8 0.072 11.5 0.8 1.3 1 0 0 1 1 1 0 Haemagglutinin SOAR PF16533.5 CDO71990.1 - 0.057 13.4 8.5 0.13 12.2 8.5 1.7 1 0 0 1 1 1 0 STIM1 Orai1-activating region FPP PF05911.11 CDO71990.1 - 0.063 11.5 14.9 0.083 11.1 14.9 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF3584 PF12128.8 CDO71990.1 - 0.16 9.4 18.2 0.21 9.0 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.8 CDO71990.1 - 0.17 12.0 15.5 0.3 11.2 15.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF489 PF04356.12 CDO71990.1 - 0.27 11.2 4.4 0.48 10.4 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF489) ATP-synt_B PF00430.18 CDO71990.1 - 0.44 10.6 17.4 1.2 9.3 17.4 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Atg14 PF10186.9 CDO71990.1 - 0.59 9.2 10.9 0.87 8.6 10.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 CDO71990.1 - 0.7 10.1 25.5 22 5.2 25.5 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 CDO71990.1 - 1.1 7.1 8.6 1.4 6.7 8.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Perilipin PF03036.16 CDO71990.1 - 1.4 7.9 12.6 2.1 7.3 12.6 1.2 1 0 0 1 1 1 0 Perilipin family BST2 PF16716.5 CDO71990.1 - 1.7 9.3 16.8 1.7 9.3 9.3 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF3450 PF11932.8 CDO71990.1 - 1.7 7.9 18.9 3.7 6.8 18.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) FapA PF03961.13 CDO71990.1 - 1.8 7.1 7.6 2.8 6.5 7.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A ALMT PF11744.8 CDO71990.1 - 2.5 6.8 9.8 3.4 6.4 9.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Exonuc_VII_L PF02601.15 CDO71990.1 - 3.2 7.2 13.3 4.8 6.7 13.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit EF-G-binding_N PF07299.11 CDO71990.1 - 3.6 8.2 6.2 2 9.0 0.9 3.0 3 1 1 4 4 3 0 Elongation factor G-binding protein, N-terminal TINF2_N PF14973.6 CDO71990.1 - 4 7.8 8.2 2.6 8.4 0.2 2.4 1 1 1 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus Vfa1 PF08432.10 CDO71990.1 - 6.3 7.1 12.1 10 6.4 12.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Snapin_Pallidin PF14712.6 CDO71990.1 - 8.3 6.9 14.7 3.3 8.2 1.0 2.5 1 1 1 2 2 2 0 Snapin/Pallidin RT_RNaseH PF17917.1 CDO71992.1 - 6.9e-24 84.2 0.0 1.4e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDO71992.1 - 4.4e-16 58.7 0.7 9.5e-16 57.7 0.7 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CDO71992.1 - 2e-15 56.7 0.0 3.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO71992.1 - 3.9e-14 52.7 0.0 6.9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CDO71992.1 - 2.3e-07 30.6 0.0 4.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 CDO71992.1 - 2.1e-06 27.9 0.1 2.1e-06 27.9 0.1 2.1 2 0 0 2 2 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 CDO71992.1 - 5.6e-06 26.8 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO71992.1 - 0.00021 21.9 0.0 0.00054 20.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 CDO71992.1 - 0.00022 21.2 1.5 0.00044 20.2 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDO71992.1 - 0.0012 18.6 0.8 0.0023 17.7 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.10 CDO71992.1 - 0.012 15.8 0.5 0.025 14.8 0.5 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 CDO71992.1 - 0.028 14.2 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease EcoEI_R_C PF08463.10 CDO71994.1 - 0.11 12.6 0.2 0.52 10.4 0.1 2.0 2 0 0 2 2 2 0 EcoEI R protein C-terminal NOA36 PF06524.12 CDO71996.1 - 0.23 10.7 12.4 0.59 9.4 12.4 1.6 1 0 0 1 1 1 0 NOA36 protein PAT1 PF09770.9 CDO71996.1 - 3.3 5.8 11.4 0.39 8.9 4.7 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Plavaka PF18759.1 CDO71997.1 - 2.7e-118 394.9 0.0 3.9e-118 394.4 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF3450 PF11932.8 CDO71999.1 - 0.001 18.5 13.8 0.0016 17.8 13.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CALCOCO1 PF07888.11 CDO71999.1 - 0.011 14.7 21.9 0.015 14.2 21.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like APG6_N PF17675.1 CDO71999.1 - 0.013 16.0 15.6 0.026 15.1 15.6 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 CDO71999.1 - 0.017 15.3 14.8 0.017 15.3 14.8 1.6 2 0 0 2 2 2 0 Tropomyosin like Atg14 PF10186.9 CDO71999.1 - 0.032 13.3 10.0 0.049 12.7 10.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5082 PF16888.5 CDO71999.1 - 0.051 13.9 14.9 0.082 13.2 6.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4200 PF13863.6 CDO71999.1 - 0.075 13.4 14.6 0.23 11.9 10.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3584 PF12128.8 CDO71999.1 - 0.075 10.5 22.1 0.014 12.9 9.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Prominin PF05478.11 CDO71999.1 - 0.16 9.9 10.2 0.24 9.3 10.2 1.2 1 0 0 1 1 1 0 Prominin DUF2175 PF09943.9 CDO71999.1 - 0.16 12.3 7.1 0.68 10.3 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) LMBR1 PF04791.16 CDO71999.1 - 0.46 9.3 4.3 0.58 9.0 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 CDO71999.1 - 0.46 9.3 22.5 0.75 8.6 10.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TSNAXIP1_N PF15739.5 CDO71999.1 - 0.61 10.5 9.3 0.13 12.7 3.1 2.4 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus ERM PF00769.19 CDO71999.1 - 0.9 9.3 23.5 5.3 6.8 23.5 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 CDO71999.1 - 0.93 9.5 16.2 4.2 7.4 16.2 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nsp1_C PF05064.13 CDO71999.1 - 0.95 9.3 7.9 19 5.1 7.9 2.4 1 1 0 1 1 1 0 Nsp1-like C-terminal region ATG16 PF08614.11 CDO71999.1 - 0.96 9.6 26.2 0.23 11.7 14.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HemY_N PF07219.13 CDO71999.1 - 1.2 9.4 9.6 0.22 11.7 2.1 2.7 1 1 1 2 2 2 0 HemY protein N-terminus TMCO5 PF14992.6 CDO71999.1 - 1.8 8.1 13.6 6.1 6.3 13.6 1.7 1 1 0 1 1 1 0 TMCO5 family Lebercilin PF15619.6 CDO71999.1 - 2.1 8.0 23.5 4.2 7.0 12.2 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fmp27_WPPW PF10359.9 CDO71999.1 - 2.7 6.7 10.5 4.3 6.1 10.5 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cob_adeno_trans PF01923.18 CDO71999.1 - 3.2 7.9 9.2 4.8 7.3 4.8 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DDE_Tnp_1_6 PF13751.6 CDO71999.1 - 3.5 7.9 7.4 4.2 7.6 6.0 1.9 1 1 0 1 1 1 0 Transposase DDE domain Fib_alpha PF08702.10 CDO71999.1 - 3.6 7.8 14.3 2 8.6 5.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1043 PF06295.12 CDO71999.1 - 3.6 7.6 14.1 4.3 7.4 10.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF745 PF05335.13 CDO71999.1 - 3.9 7.2 18.7 2.3 7.9 12.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) BLOC1_2 PF10046.9 CDO71999.1 - 4.8 7.5 12.4 2.1 8.7 3.3 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 CDO71999.1 - 6.9 6.7 10.7 2.8 8.0 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 CDO71999.1 - 9.1 4.1 9.5 12 3.6 9.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GPI-anchored PF10342.9 CDO72000.1 - 3.6e-05 24.4 0.5 7.7e-05 23.4 0.5 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PARP PF00644.20 CDO72001.1 - 2.4e-13 50.1 0.0 5.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 CDO72001.1 - 0.023 14.3 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Opiods_neuropep PF01160.18 CDO72001.1 - 7.5 6.7 6.9 3.2 7.9 3.5 2.2 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide Pkinase PF00069.25 CDO72002.1 - 1.2e-10 41.3 0.0 2.3e-10 40.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Peptidase_A4 PF01828.17 CDO72003.1 - 3.5e-79 265.1 15.4 5.5e-79 264.5 15.4 1.3 1 0 0 1 1 1 1 Peptidase A4 family Bac_chlorC PF02043.17 CDO72004.1 - 1.1 9.3 6.5 0.54 10.3 0.9 2.0 1 1 1 2 2 2 0 Bacteriochlorophyll C binding protein Ank_2 PF12796.7 CDO72005.1 - 8.9e-26 90.3 0.1 6.9e-07 29.8 0.0 5.6 3 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDO72005.1 - 2.4e-18 66.2 0.2 0.00017 22.1 0.0 6.9 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDO72005.1 - 6.5e-18 63.0 0.1 0.0093 16.4 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 CDO72005.1 - 7.8e-15 54.8 0.9 0.0028 17.9 0.0 7.0 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 CDO72005.1 - 6.3e-14 51.7 2.2 0.036 14.5 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat DUF1843 PF08898.10 CDO72005.1 - 0.029 14.9 0.2 64 4.2 0.0 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Adipogenin PF15202.6 CDO72006.1 - 0.21 11.7 1.2 4.2 7.5 0.0 2.9 3 0 0 3 3 3 0 Adipogenin DUF3328 PF11807.8 CDO72009.1 - 2.2e-18 66.8 0.5 4e-18 66.0 0.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1265 PF06887.14 CDO72009.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) DUF3328 PF11807.8 CDO72010.1 - 7.5e-17 61.8 0.9 5.9e-16 58.9 0.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) DDE_3 PF13358.6 CDO72012.1 - 1.3e-06 28.3 0.1 0.012 15.4 0.0 3.1 3 0 0 3 3 3 3 DDE superfamily endonuclease MFS_1 PF07690.16 CDO72013.1 - 2.4e-37 128.7 52.8 5.4e-36 124.2 53.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO72013.1 - 8.1e-15 54.3 8.1 2.1e-13 49.6 11.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CDO72013.1 - 4.3e-13 48.9 12.0 4.3e-13 48.9 12.0 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 CDO72013.1 - 2.5 6.3 18.5 1.4 7.2 3.7 3.9 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Beta-lactamase PF00144.24 CDO72014.1 - 1.1e-43 149.7 0.2 1.5e-43 149.4 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase DDE_3 PF13358.6 CDO72015.1 - 3e-11 43.3 0.9 3.8e-11 42.9 0.9 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Beta-lactamase PF00144.24 CDO72016.1 - 1.3e-38 133.1 0.7 2.2e-38 132.3 0.7 1.3 1 0 0 1 1 1 1 Beta-lactamase ThrE PF06738.12 CDO72017.1 - 1.1e-54 185.4 16.2 2.3e-54 184.4 4.8 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CDO72017.1 - 2.3e-10 40.7 2.3 2.3e-10 40.7 2.3 2.3 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE DUF3552 PF12072.8 CDO72018.1 - 0.013 14.9 11.4 0.022 14.2 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2884 PF11101.8 CDO72018.1 - 0.11 11.9 4.7 0.15 11.5 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) MPS2 PF17060.5 CDO72018.1 - 0.19 11.0 0.5 0.3 10.3 0.5 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 FAM76 PF16046.5 CDO72018.1 - 0.38 10.1 4.8 0.98 8.7 4.5 1.6 1 1 0 1 1 1 0 FAM76 protein YabA PF06156.13 CDO72018.1 - 0.45 11.2 6.2 0.64 10.7 5.0 1.9 2 0 0 2 2 2 0 Initiation control protein YabA AAA_13 PF13166.6 CDO72018.1 - 0.68 8.5 7.5 0.89 8.1 7.5 1.1 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 CDO72018.1 - 9.2 5.3 7.5 15 4.6 7.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Elf1 PF05129.13 CDO72020.1 - 1.9 8.6 4.6 0.83 9.7 0.5 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like RT_RNaseH_2 PF17919.1 CDO72021.1 - 8.6e-11 41.8 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO72021.1 - 3e-07 30.7 0.0 4.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDO72022.1 - 0.00055 20.4 0.0 0.0015 19.1 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO72022.1 - 0.0067 17.0 0.0 0.014 16.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CDO72022.1 - 0.045 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease HAMP PF00672.25 CDO72025.1 - 5.8e-15 55.4 9.4 2.1e-07 31.2 0.2 4.5 6 0 0 6 6 6 2 HAMP domain Baculo_PEP_C PF04513.12 CDO72025.1 - 0.0012 18.9 5.3 0.37 10.8 0.1 3.0 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 CDO72025.1 - 0.037 14.2 0.2 13 6.0 0.1 3.5 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 CDO72025.1 - 0.6 10.4 14.2 16 5.8 0.9 5.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) HATPase_c PF02518.26 CDO72026.1 - 8.6e-30 103.5 0.5 2.4e-29 102.1 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 CDO72026.1 - 3.9e-29 100.8 10.3 1.3e-07 31.9 0.1 5.1 4 0 0 4 4 4 4 HAMP domain Response_reg PF00072.24 CDO72026.1 - 3.8e-26 91.4 0.5 4.4e-24 84.8 0.2 2.9 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 CDO72026.1 - 7e-16 58.0 2.1 1.8e-15 56.7 1.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 CDO72026.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CENP-F_leu_zip PF10473.9 CDO72026.1 - 2.2 8.3 4.9 12 5.9 1.0 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_C13 PF01650.18 CDO72027.1 - 2e-43 148.8 0.1 2.5e-43 148.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 CDO72027.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute Pyr_redox_2 PF07992.14 CDO72029.1 - 1.6e-24 86.6 0.0 1.5e-21 76.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDO72029.1 - 5.2e-09 36.5 0.0 1.6e-07 31.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDO72029.1 - 0.026 13.7 0.1 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CDO72029.1 - 0.096 12.9 0.8 8.3 6.7 0.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF2545 PF10810.8 CDO72030.1 - 0.019 15.1 0.5 0.019 15.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2545) Phage_holin_3_6 PF07332.11 CDO72030.1 - 0.44 10.6 17.3 1.8 8.6 0.4 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_M20 PF01546.28 CDO72031.1 - 8.9e-08 32.1 0.3 1.9e-07 31.0 0.3 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDO72031.1 - 1.9e-06 27.7 0.0 5.9e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain FSH1 PF03959.13 CDO72032.1 - 2.1e-45 155.0 0.0 1.5e-43 149.0 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Cyd_oper_YbgE PF09600.10 CDO72032.1 - 0.019 15.4 0.8 0.058 13.8 0.2 2.1 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) DUF2235 PF09994.9 CDO72032.1 - 0.047 13.0 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DLH PF01738.18 CDO72032.1 - 0.07 12.7 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CDO72032.1 - 0.093 12.4 0.0 3.7 7.1 0.0 2.5 2 1 0 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CDO72032.1 - 0.56 10.0 1.4 2 8.1 1.3 2.0 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Bromodomain PF00439.25 CDO72033.1 - 2e-23 82.2 0.0 3.7e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain FA_desaturase PF00487.24 CDO72035.1 - 2.6 7.8 5.1 0.61 9.9 0.3 2.2 1 1 1 2 2 2 0 Fatty acid desaturase NUP PF06516.11 CDO72036.1 - 3.2e-123 410.9 0.0 3.6e-123 410.8 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Glyco_transf_15 PF01793.16 CDO72037.1 - 4.9e-108 361.2 8.1 1.3e-74 251.4 6.2 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Acid_PPase PF12689.7 CDO72039.1 - 5.6e-32 110.9 0.0 5.1e-30 104.5 0.0 2.0 1 1 1 2 2 2 2 Acid Phosphatase F-box-like PF12937.7 CDO72040.1 - 1.1e-08 34.8 3.2 1.1e-08 34.8 3.2 2.7 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.7 CDO72040.1 - 0.0062 16.9 2.1 0.77 10.3 0.1 4.7 3 2 4 7 7 7 2 Leucine Rich repeats (2 copies) Hva1_TUDOR PF11160.8 CDO72041.1 - 1.8e-12 47.2 1.6 3.6e-12 46.3 1.6 1.4 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Dimer_Tnp_hAT PF05699.14 CDO72042.1 - 7e-16 57.8 0.0 1.4e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 CDO72042.1 - 0.0017 18.7 0.2 0.0043 17.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DUF659 PF04937.15 CDO72042.1 - 0.013 15.4 0.1 0.032 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) DUF2197 PF09963.9 CDO72042.1 - 0.13 12.6 0.1 0.4 11.0 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) HBS1_N PF08938.10 CDO72042.1 - 0.77 10.1 4.5 3 8.2 0.5 3.3 3 0 0 3 3 3 0 HBS1 N-terminus Dimer_Tnp_hAT PF05699.14 CDO72044.1 - 1.6e-13 50.2 0.0 4.8e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Abhydrolase_6 PF12697.7 CDO72045.1 - 6e-10 40.1 1.0 6e-10 40.1 1.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO72045.1 - 1.1e-09 37.9 0.0 3.8e-08 32.9 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CDO72045.1 - 6.3e-08 32.7 0.0 1.5e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CDO72045.1 - 1.2e-07 31.6 0.0 3e-06 27.1 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CDO72045.1 - 0.0014 18.8 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain DUF818 PF05677.12 CDO72045.1 - 0.021 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Peptidase_S15 PF02129.18 CDO72045.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ser_hydrolase PF06821.13 CDO72045.1 - 0.059 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.13 CDO72045.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 CDO72045.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family HCO3_cotransp PF00955.21 CDO72046.1 - 3.8e-70 237.2 5.2 4.1e-32 111.7 3.5 3.2 2 1 0 3 3 3 3 HCO3- transporter family FMO-like PF00743.19 CDO72046.1 - 5.7e-30 104.2 0.0 7.5e-19 67.5 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CDO72046.1 - 2.9e-06 26.7 0.2 0.012 14.9 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CDO72046.1 - 2.3e-05 23.8 0.0 0.00092 18.5 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sulfate_transp PF00916.20 CDO72046.1 - 0.00073 18.4 2.8 0.0011 17.8 0.7 2.0 2 0 0 2 2 2 1 Sulfate permease family NAD_binding_8 PF13450.6 CDO72046.1 - 0.00098 19.3 0.5 0.015 15.5 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CDO72046.1 - 0.0036 17.3 3.0 0.011 15.7 0.0 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 CDO72046.1 - 0.0073 15.6 0.1 0.38 10.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family EHN PF06441.12 CDO72047.1 - 3.4e-33 114.2 2.2 1.3e-32 112.4 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CDO72047.1 - 1.9e-13 50.6 0.1 3.3e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO72047.1 - 9.2e-05 23.1 5.0 0.00024 21.8 5.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family NTP_transf_5 PF14907.6 CDO72047.1 - 0.2 11.2 0.6 0.59 9.7 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase EHN PF06441.12 CDO72048.1 - 5.4e-33 113.6 1.1 1.9e-32 111.8 0.3 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CDO72048.1 - 6.9e-13 48.8 0.1 1.2e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO72048.1 - 0.0029 18.2 2.0 0.0029 18.2 2.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family EHN PF06441.12 CDO72049.1 - 4.7e-31 107.3 0.1 4.7e-31 107.3 0.1 2.8 3 0 0 3 3 3 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CDO72049.1 - 5e-05 23.1 0.1 9.4e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO72049.1 - 0.0038 17.8 4.0 0.018 15.7 4.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family V_ATPase_I PF01496.19 CDO72049.1 - 1.9 6.3 5.3 3.6 5.4 5.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family stn_TNFRSF12A PF12191.8 CDO72051.1 - 0.00049 20.3 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain CEND1 PF15677.5 CDO72051.1 - 0.041 14.4 0.2 0.041 14.4 0.2 1.9 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 RCR PF12273.8 CDO72051.1 - 0.067 13.9 1.7 0.38 11.4 1.7 2.3 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TrbC PF04956.13 CDO72051.1 - 0.087 13.0 0.4 0.19 12.0 0.4 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family Acetyltransf_2 PF00797.17 CDO72051.1 - 0.18 11.6 0.0 0.44 10.3 0.0 1.6 2 0 0 2 2 2 0 N-acetyltransferase Epimerase PF01370.21 CDO72054.1 - 1.5e-17 63.9 0.0 1.6e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDO72054.1 - 2.4e-13 50.2 0.0 3.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDO72054.1 - 3.3e-10 39.5 0.0 4.6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDO72054.1 - 7e-07 28.6 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CDO72054.1 - 2.8e-06 26.7 0.0 0.0041 16.3 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 CDO72054.1 - 0.00051 20.0 0.1 0.0011 19.0 0.0 1.5 1 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 CDO72054.1 - 0.00067 19.2 0.0 0.0012 18.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 CDO72054.1 - 0.017 14.3 0.0 1.2 8.2 0.0 2.6 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 CDO72054.1 - 0.063 12.8 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Enterotoxin_a PF01375.17 CDO72054.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain F_bP_aldolase PF01116.20 CDO72055.1 - 1.1e-75 254.8 0.0 1.2e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Aminotran_1_2 PF00155.21 CDO72056.1 - 1.5e-27 96.7 0.0 2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CDO72056.1 - 0.0028 16.2 0.0 0.0043 15.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CDO72056.1 - 0.037 13.0 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CDO72056.1 - 0.063 12.6 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CDO72056.1 - 0.074 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase MerR PF00376.23 CDO72056.1 - 0.17 11.7 0.0 0.67 9.8 0.0 2.0 1 0 0 1 1 1 0 MerR family regulatory protein RVT_1 PF00078.27 CDO72057.1 - 3.2e-36 124.9 0.0 5e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO72057.1 - 1.6e-20 73.1 0.0 3.9e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 CDO72057.1 - 5.5e-09 36.3 0.0 1.6e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 RNase H Exo_endo_phos PF03372.23 CDO72057.1 - 7.9e-09 35.4 1.2 1.8e-08 34.2 1.2 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 CDO72057.1 - 0.0057 17.3 0.1 0.017 15.8 0.1 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Plavaka PF18759.1 CDO72059.1 - 1.6e-13 50.6 0.0 2.1e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 CDO72062.1 - 1e-75 255.0 4.1 1.6e-54 185.3 3.9 3.0 1 1 1 2 2 2 2 Plavaka transposase rve PF00665.26 CDO72064.1 - 2.4e-17 63.2 0.0 4.8e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO72064.1 - 4.1e-11 42.7 0.1 4.6e-10 39.3 0.1 2.2 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO72064.1 - 0.00021 21.1 0.2 0.00059 19.7 0.2 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO72064.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RVT_2 PF07727.14 CDO72065.1 - 3.2e-48 164.5 0.1 4.7e-48 163.9 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_60s PF00428.19 CDO72066.1 - 0.00019 21.9 0.2 0.00025 21.6 0.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Na_Ca_ex_C PF16494.5 CDO72067.1 - 0.085 13.3 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Peptidase_M20 PF01546.28 CDO72068.1 - 1.4e-25 90.2 0.0 2.9e-25 89.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDO72068.1 - 2e-12 47.0 0.5 6.7e-12 45.3 0.3 2.0 2 1 0 2 2 2 1 Peptidase dimerisation domain UQ_con PF00179.26 CDO72069.1 - 6.5e-14 51.8 0.1 1.1e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ATP_sub_h PF10775.9 CDO72069.1 - 0.03 14.3 2.7 0.07 13.1 2.6 1.7 1 1 0 1 1 1 0 ATP synthase complex subunit h NUDE_C PF04880.13 CDO72069.1 - 2.6 8.5 5.7 3.7 8.0 5.7 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DAP3 PF10236.9 CDO72071.1 - 1.2e-68 231.5 0.0 1.5e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CDO72071.1 - 1.9e-06 28.4 0.0 3.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 CDO72071.1 - 0.0091 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 CDO72071.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CDO72071.1 - 0.04 14.2 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CDO72071.1 - 0.076 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CDO72071.1 - 0.083 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDO72071.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 CDO72071.1 - 0.1 12.9 0.0 0.33 11.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 CDO72071.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 CDO72071.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.7 CDO72071.1 - 0.16 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Kinesin PF00225.23 CDO72072.1 - 5.4e-103 344.4 0.3 9.2e-103 343.7 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDO72072.1 - 2.8e-52 176.6 0.0 4.7e-51 172.7 0.0 2.6 1 1 0 1 1 1 1 Microtubule binding HIP1_clath_bdg PF16515.5 CDO72072.1 - 0.0032 18.1 9.8 0.0032 18.1 9.8 3.8 3 1 2 5 5 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_DNA_bd PF12329.8 CDO72072.1 - 0.014 15.4 5.0 0.014 15.4 5.0 4.1 5 1 1 6 6 6 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 CDO72072.1 - 0.056 12.9 21.1 0.13 11.8 21.1 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 XLF PF09302.11 CDO72072.1 - 0.52 10.4 5.4 0.39 10.8 0.8 2.8 3 1 0 3 3 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component FAM76 PF16046.5 CDO72072.1 - 0.63 9.3 9.8 1.5 8.1 9.8 1.6 1 0 0 1 1 1 0 FAM76 protein SHE3 PF17078.5 CDO72072.1 - 1.1 8.9 17.3 0.67 9.6 10.9 2.6 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 CDO72072.1 - 1.1 9.3 25.6 0.19 11.8 14.3 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.9 CDO72072.1 - 2.2 6.7 23.3 1.2 7.6 8.9 2.2 1 1 1 2 2 2 0 Macoilin family KxDL PF10241.9 CDO72072.1 - 2.3 8.5 14.5 9.7 6.6 5.8 4.1 2 1 1 3 3 3 0 Uncharacterized conserved protein Spc7 PF08317.11 CDO72072.1 - 2.8 6.8 28.6 0.83 8.5 20.0 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Lebercilin PF15619.6 CDO72072.1 - 4.5 6.9 31.0 45 3.6 30.0 2.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease T2SSN PF01203.19 CDO72072.1 - 4.9 7.3 9.6 0.5 10.6 4.7 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein N DUF3584 PF12128.8 CDO72072.1 - 8.9 3.7 26.4 14 3.1 26.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 CDO72072.1 - 9.2 6.8 32.5 0.97 10.0 6.4 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region Exo_endo_phos PF03372.23 CDO72073.1 - 8.7e-11 41.8 0.1 2.1e-10 40.5 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 CDO72073.1 - 1.8e-08 34.3 3.9 9.2e-06 25.7 0.6 2.5 2 0 0 2 2 2 2 GRF zinc finger Exo_endo_phos_2 PF14529.6 CDO72073.1 - 0.014 15.2 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase zf-C2H2_jaz PF12171.8 CDO72074.1 - 3.6e-10 39.9 5.7 5.5e-10 39.3 5.7 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CDO72074.1 - 0.0032 17.8 0.2 0.0054 17.0 0.2 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CDO72074.1 - 0.059 14.2 1.3 0.059 14.2 1.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger UPAR_LY6_2 PF16975.5 CDO72074.1 - 0.073 13.3 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 zf-met PF12874.7 CDO72074.1 - 0.17 12.3 3.6 0.32 11.4 3.6 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Anoctamin PF04547.12 CDO72077.1 - 4.7e-105 352.0 2.8 6e-105 351.7 2.8 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel VHS PF00790.19 CDO72078.1 - 9.1e-34 116.3 0.1 1.4e-33 115.7 0.1 1.3 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 CDO72078.1 - 7.4e-15 54.3 0.0 1.3e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDO72078.1 - 2.4e-14 52.7 0.1 4.9e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CDO72078.1 - 3.7e-14 52.3 0.1 7.5e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 CDO72078.1 - 2.5e-13 50.1 0.8 5.4e-13 49.1 0.8 1.6 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 CDO72078.1 - 0.0078 16.1 5.2 0.018 14.9 5.2 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif IKBKB_SDD PF18397.1 CDO72078.1 - 0.11 11.7 0.2 0.19 11.0 0.2 1.2 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain UQ_con PF00179.26 CDO72079.1 - 5.2e-17 61.8 0.0 5.6e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDO72079.1 - 0.0035 17.6 0.0 0.0037 17.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 CDO72079.1 - 0.11 12.3 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 UEV domain Sugar_tr PF00083.24 CDO72080.1 - 1.7e-76 258.0 19.4 1.9e-76 257.8 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO72080.1 - 4.6e-32 111.3 31.4 2.2e-31 109.1 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CDO72080.1 - 4.7e-10 38.5 12.0 2e-08 33.1 1.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 CDO72080.1 - 1.6e-06 27.6 14.3 4.5e-06 26.2 3.6 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF3792 PF12670.7 CDO72080.1 - 0.018 15.2 16.0 0.047 13.9 3.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) OATP PF03137.20 CDO72080.1 - 0.29 9.4 13.0 0.06 11.6 0.8 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Sec6 PF06046.13 CDO72081.1 - 1.3e-155 519.0 6.1 1.3e-155 519.0 6.1 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.12 CDO72081.1 - 0.00088 18.3 1.1 0.0089 15.0 0.4 2.5 2 0 0 2 2 2 1 Vps53-like, N-terminal HECT PF00632.25 CDO72081.1 - 0.003 17.1 0.0 0.0068 15.9 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ACDC PF14733.6 CDO72081.1 - 0.0048 17.2 0.0 0.029 14.7 0.0 2.4 1 1 1 2 2 2 1 AP2-coincident C-terminal SKA2 PF16740.5 CDO72081.1 - 0.036 13.8 5.6 0.96 9.3 2.0 3.7 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Vps5 PF09325.10 CDO72081.1 - 0.045 13.3 6.3 0.11 12.1 0.5 2.9 3 0 0 3 3 3 0 Vps5 C terminal like Vps51 PF08700.11 CDO72081.1 - 0.36 11.0 6.3 0.78 9.9 0.0 4.4 4 1 0 4 4 4 0 Vps51/Vps67 DUF3348 PF11828.8 CDO72081.1 - 0.95 9.1 8.0 0.27 10.9 0.2 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3348) COG2 PF06148.11 CDO72081.1 - 3.9 7.6 15.0 7.8 6.6 0.0 5.9 6 1 1 7 7 7 0 COG (conserved oligomeric Golgi) complex component, COG2 MFS_1 PF07690.16 CDO72082.1 - 3e-33 115.2 28.4 3e-33 115.2 28.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO72082.1 - 4.7e-06 25.7 8.7 4.7e-06 25.7 8.7 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter DUF2101 PF09874.9 CDO72082.1 - 0.029 14.1 0.5 0.051 13.3 0.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) CN_hydrolase PF00795.22 CDO72083.1 - 2.1e-37 128.9 0.0 3.4e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 CDO72083.1 - 2.3e-23 82.6 0.0 7.1e-23 81.0 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Lycopene_cycl PF05834.12 CDO72085.1 - 2.6e-07 30.0 0.6 1.8e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 CDO72085.1 - 5.5e-06 25.8 0.0 2.4e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 CDO72085.1 - 1.2e-05 25.1 1.1 4.1e-05 23.3 1.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDO72085.1 - 1.5e-05 24.4 0.1 3.7e-05 23.1 0.1 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO72085.1 - 1.5e-05 25.0 0.2 0.00012 22.1 0.2 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 CDO72085.1 - 0.00015 21.2 2.5 0.00036 19.9 2.5 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CDO72085.1 - 0.00052 19.4 0.0 0.0045 16.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO72085.1 - 0.0015 18.7 0.1 0.0039 17.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CDO72085.1 - 0.003 16.5 0.4 0.0054 15.6 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 CDO72085.1 - 0.01 14.9 1.3 0.017 14.3 0.6 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 CDO72085.1 - 0.015 14.0 0.8 0.027 13.2 0.8 1.7 1 1 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 CDO72085.1 - 0.019 14.3 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDO72085.1 - 0.063 13.8 0.2 0.43 11.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lsm_C PF14894.6 CDO72085.1 - 0.066 13.0 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Lsm C-terminal DUF4147 PF13660.6 CDO72085.1 - 0.073 12.6 0.1 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) K_oxygenase PF13434.6 CDO72085.1 - 0.14 11.2 0.2 0.26 10.4 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UDPGT PF00201.18 CDO72086.1 - 1.7e-06 27.1 0.0 2.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO72086.1 - 0.0048 16.9 0.1 0.0068 16.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ACC_central PF08326.12 CDO72088.1 - 1.2e-253 843.7 0.0 1.5e-253 843.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CDO72088.1 - 2.6e-173 577.2 0.0 3.4e-173 576.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CDO72088.1 - 6.7e-53 179.3 0.0 1.6e-52 178.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CDO72088.1 - 3.9e-30 104.6 0.1 8.4e-30 103.6 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CDO72088.1 - 4.9e-21 74.8 0.0 3.1e-20 72.3 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CDO72088.1 - 2.2e-13 49.8 0.0 4.5e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 CDO72088.1 - 0.00019 21.5 0.0 0.00071 19.7 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CDO72088.1 - 0.00044 19.9 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CDO72088.1 - 0.034 13.7 0.1 0.076 12.6 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 CDO72088.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Fer2_4 PF13510.6 CDO72088.1 - 0.11 12.6 0.1 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Biotin_lipoyl_2 PF13533.6 CDO72088.1 - 0.14 12.0 0.0 0.64 9.9 0.0 2.1 1 0 0 1 1 1 0 Biotin-lipoyl like Ribosomal_L35Ae PF01247.18 CDO72089.1 - 2e-44 149.7 0.4 2.3e-44 149.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CDO72089.1 - 0.00046 20.4 0.0 0.089 13.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain ArgJ PF01960.18 CDO72090.1 - 2.3e-149 497.2 0.0 2.6e-149 497.0 0.0 1.0 1 0 0 1 1 1 1 ArgJ family PH_10 PF15411.6 CDO72091.1 - 1.3e-23 83.6 0.0 2.3e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 CDO72091.1 - 0.00011 22.5 0.0 0.00028 21.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CDO72091.1 - 0.0014 18.6 0.1 0.0061 16.5 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 CDO72092.1 - 0.0027 18.0 0.3 0.0053 17.1 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CDO72092.1 - 0.0051 16.8 1.8 0.01 15.8 1.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CDO72092.1 - 0.31 10.8 2.1 1.2 8.9 2.1 1.9 1 1 0 1 1 1 0 RING-like zinc finger Pkinase_fungal PF17667.1 CDO72093.1 - 1.2e-28 100.0 0.0 1.6e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF4129 PF13559.6 CDO72093.1 - 0.1 12.9 1.5 0.37 11.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Asp PF00026.23 CDO72095.1 - 4.2e-10 39.5 0.0 6.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Protocadherin PF08374.11 CDO72095.1 - 0.25 11.3 1.3 0.35 10.8 0.4 1.6 1 1 1 2 2 2 0 Protocadherin COX7C PF02935.16 CDO72096.1 - 0.0069 16.6 0.3 0.14 12.4 0.2 2.3 2 0 0 2 2 2 1 Cytochrome c oxidase subunit VIIc HIG_1_N PF04588.13 CDO72097.1 - 9.1e-13 48.2 0.2 1.4e-12 47.7 0.2 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2076 PF09849.9 CDO72097.1 - 0.018 15.1 0.5 0.025 14.6 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cgr1 PF03879.14 CDO72097.1 - 2.2 8.7 6.5 3.7 8.0 6.5 1.3 1 0 0 1 1 1 0 Cgr1 family Urm1 PF09138.11 CDO72098.1 - 1.8e-34 117.9 0.0 2.8e-28 98.1 0.0 2.1 2 0 0 2 2 2 2 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CDO72098.1 - 0.00017 22.1 0.0 0.00026 21.5 0.0 1.4 1 0 0 1 1 1 1 ThiS family RVT_2 PF07727.14 CDO72100.1 - 6.3e-09 35.8 0.0 8.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CDO72101.1 - 2.8e-16 59.4 3.7 3.4e-16 59.2 2.2 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 CDO72101.1 - 9.3e-06 25.4 0.1 2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.6 CDO72101.1 - 0.0024 17.6 2.6 0.0049 16.7 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4219 PF13961.6 CDO72101.1 - 0.0041 16.8 0.4 0.0041 16.8 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.23 CDO72101.1 - 0.0047 17.0 2.6 0.0047 17.0 2.6 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 CDO72101.1 - 0.032 14.1 3.4 0.07 13.0 3.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Peroxidase_2 PF01328.17 CDO72103.1 - 6.3e-43 147.5 0.0 2e-42 145.9 0.0 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 Sds3 PF08598.11 CDO72105.1 - 2.2e-23 83.4 2.6 7.7e-23 81.6 2.6 2.0 1 0 0 1 1 1 1 Sds3-like Peroxidase_2 PF01328.17 CDO72106.1 - 1.3e-49 169.2 0.0 1.9e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 NUDIX PF00293.28 CDO72107.1 - 3.4e-10 40.1 0.0 7.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 CDO72107.1 - 5.1e-07 29.7 0.0 0.00082 19.3 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4743) RNA_Me_trans PF04252.13 CDO72108.1 - 1.8e-74 249.6 0.0 1.1e-73 247.1 0.0 1.8 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Aldo_ket_red PF00248.21 CDO72109.1 - 2.7e-66 223.7 0.0 3.4e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNA_binding PF01877.17 CDO72109.1 - 0.13 12.6 0.0 0.38 11.0 0.0 1.7 2 0 0 2 2 2 0 RNA binding Aldo_ket_red PF00248.21 CDO72110.1 - 9.6e-67 225.2 0.1 1.3e-66 224.8 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNA_binding PF01877.17 CDO72110.1 - 0.17 12.2 0.1 0.61 10.4 0.0 1.9 2 0 0 2 2 2 0 RNA binding TPR_19 PF14559.6 CDO72111.1 - 3.3e-08 33.9 3.0 0.00079 19.9 0.0 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDO72111.1 - 3.7e-07 30.2 5.0 0.00041 20.4 0.4 3.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDO72111.1 - 7.2e-07 28.9 1.8 0.055 13.6 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDO72111.1 - 1.2e-06 28.1 0.3 0.085 12.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDO72111.1 - 1e-05 25.9 3.8 0.0008 20.0 0.2 4.6 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDO72111.1 - 4.7e-05 23.3 0.5 0.26 11.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO72111.1 - 5.8e-05 22.7 0.1 0.041 13.6 0.2 2.7 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 CDO72111.1 - 0.0021 18.7 2.6 0.5 11.1 0.0 4.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDO72111.1 - 0.0023 18.2 3.5 1.1 9.6 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF5601 PF18151.1 CDO72111.1 - 0.02 15.2 0.0 0.056 13.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) ChAPs PF09295.10 CDO72111.1 - 0.038 13.0 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.6 CDO72111.1 - 0.048 14.1 0.8 7.5 7.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 CDO72111.1 - 0.15 11.8 0.6 24 4.6 0.0 2.5 2 1 1 3 3 3 0 26S proteasome subunit RPN7 Pterin_bind PF00809.22 CDO72112.1 - 7.2e-56 189.6 0.0 1.7e-31 109.8 0.0 2.3 2 0 0 2 2 2 2 Pterin binding enzyme FolB PF02152.18 CDO72112.1 - 1.6e-37 128.5 0.0 1.7e-22 80.1 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 CDO72112.1 - 1.8e-34 118.6 0.0 3.8e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Pkinase PF00069.25 CDO72113.1 - 4.5e-61 206.5 0.0 1.1e-60 205.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO72113.1 - 2e-44 151.8 0.0 5.1e-44 150.5 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase DUF3543 PF12063.8 CDO72113.1 - 1.4e-39 136.0 0.4 3e-39 134.9 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.6 CDO72113.1 - 0.0026 17.1 0.0 0.032 13.6 0.0 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CDO72113.1 - 0.0073 16.2 0.7 0.066 13.1 0.0 2.7 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO72113.1 - 0.11 11.2 0.0 0.27 10.0 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase UNC-79 PF14776.6 CDO72113.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Plus-3 PF03126.18 CDO72114.1 - 1.7e-37 128.3 0.1 5.2e-37 126.7 0.1 1.9 1 0 0 1 1 1 1 Plus-3 domain Sof1 PF04158.14 CDO72115.1 - 1.3e-29 102.3 11.9 2.2e-29 101.6 11.9 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 CDO72115.1 - 4.5e-21 74.8 9.9 2.1e-07 31.5 0.2 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO72115.1 - 3.5e-07 30.4 0.0 0.046 14.0 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain peroxidase PF00141.23 CDO72117.1 - 3.6e-06 26.9 0.0 4.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase F-box-like PF12937.7 CDO72119.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like DEAD PF00270.29 CDO72120.1 - 5.6e-44 150.0 0.0 1.1e-43 149.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO72120.1 - 7.4e-24 84.2 0.0 4.3e-23 81.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDO72120.1 - 1.1e-18 67.2 0.0 2.4e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) CMS1 PF14617.6 CDO72120.1 - 0.009 15.4 3.7 2.6 7.3 2.3 2.9 2 0 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DUF913 PF06025.12 CDO72120.1 - 7.1 5.5 11.2 1.2 8.0 1.6 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) AAA_5 PF07728.14 CDO72121.1 - 2.3e-64 215.5 0.0 8.3e-27 93.9 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDO72121.1 - 0.003 18.0 0.2 5 7.5 0.0 4.1 3 1 1 4 4 4 1 AAA ATPase domain AAA_lid_7 PF17867.1 CDO72121.1 - 0.005 17.0 0.1 12 6.1 0.0 3.5 3 0 0 3 3 3 2 Midasin AAA lid domain CbbQ_C PF08406.10 CDO72121.1 - 0.018 15.3 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal AAA PF00004.29 CDO72121.1 - 0.03 14.8 0.0 0.11 12.9 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MCM_lid PF17855.1 CDO72121.1 - 0.079 13.4 0.1 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 MCM AAA-lid domain AAA_2 PF07724.14 CDO72121.1 - 0.22 11.6 0.1 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Aminotran_1_2 PF00155.21 CDO72122.1 - 3.3e-38 131.8 0.0 4.2e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CDO72122.1 - 0.0081 14.7 0.0 0.019 13.5 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Myb_DNA-binding PF00249.31 CDO72125.1 - 6.9e-08 32.6 0.6 1.2e-07 31.8 0.6 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cir_N PF10197.9 CDO72125.1 - 0.00014 22.0 0.0 0.00014 22.0 0.0 3.4 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-bind_6 PF13921.6 CDO72125.1 - 0.0027 17.9 0.4 0.0076 16.5 0.4 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Polysacc_synt_4 PF04669.13 CDO72126.1 - 3.7e-21 75.5 2.7 1.6e-19 70.2 2.3 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis adh_short PF00106.25 CDO72127.1 - 1.2e-34 119.5 0.9 4.9e-32 111.0 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO72127.1 - 2.1e-34 119.1 0.1 1.5e-21 77.0 0.1 2.4 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO72127.1 - 1e-06 28.8 0.1 1.6e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CDO72127.1 - 0.0032 16.7 0.1 0.0046 16.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox PF00070.27 CDO72127.1 - 0.021 15.4 0.3 0.058 14.0 0.3 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CDO72127.1 - 0.021 14.7 0.3 0.03 14.2 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CDO72127.1 - 0.029 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Dak1 PF02733.17 CDO72127.1 - 0.75 8.6 3.8 1.6 7.6 2.0 2.2 2 1 1 3 3 3 0 Dak1 domain Thaumatin PF00314.17 CDO72128.1 - 5.2e-68 228.9 11.9 6e-68 228.7 11.9 1.0 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.21 CDO72128.1 - 0.078 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat ThiF PF00899.21 CDO72129.1 - 3e-41 141.4 0.0 4.8e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CDO72129.1 - 0.00035 20.8 1.3 0.0037 17.5 1.3 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CDO72129.1 - 0.00039 20.8 0.1 0.00091 19.6 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 CDO72129.1 - 0.0034 17.3 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CDO72129.1 - 0.031 13.8 0.1 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 CDO72129.1 - 0.072 12.4 0.3 0.13 11.5 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MTS PF05175.14 CDO72129.1 - 0.1 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DAO PF01266.24 CDO72129.1 - 0.11 12.0 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDO72129.1 - 0.12 11.5 0.3 0.2 10.9 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Vps26 PF03643.15 CDO72131.1 - 9.6e-132 438.1 2.2 1.1e-131 437.9 2.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CDO72131.1 - 0.00079 19.5 1.7 0.37 10.9 0.0 3.3 3 1 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain zf-C2H2_4 PF13894.6 CDO72132.1 - 4.1 8.5 7.5 72 4.6 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger MatC_N PF07158.11 CDO72133.1 - 0.022 14.8 0.1 0.03 14.3 0.1 1.3 1 1 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus Abhydrolase_1 PF00561.20 CDO72134.1 - 4.6e-25 88.7 0.0 2.3e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 CDO72134.1 - 1.2e-19 70.3 0.0 2.5e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 CDO72135.1 - 3.1e-17 63.1 0.0 2.8e-16 59.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 CDO72135.1 - 3.2e-05 24.0 0.1 0.0012 19.0 0.0 2.5 1 1 1 2 2 2 2 TAP-like protein CENP-Q PF13094.6 CDO72136.1 - 0.0077 16.4 4.0 0.0085 16.3 4.0 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit WAK_assoc PF14380.6 CDO72136.1 - 0.034 14.9 3.1 0.049 14.4 3.1 1.3 1 0 0 1 1 1 0 Wall-associated receptor kinase C-terminal betaPIX_CC PF16523.5 CDO72136.1 - 0.13 12.1 7.6 0.21 11.5 7.6 1.3 1 0 0 1 1 1 0 betaPIX coiled coil HU-CCDC81_bac_2 PF18175.1 CDO72136.1 - 0.24 11.3 0.7 0.45 10.4 0.7 1.4 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 DUF3619 PF12279.8 CDO72136.1 - 0.28 11.5 3.8 0.33 11.3 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF4746 PF15928.5 CDO72136.1 - 0.3 10.5 4.1 0.31 10.4 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4398 PF14346.6 CDO72136.1 - 0.32 11.7 17.5 0.42 11.3 17.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) U79_P34 PF03064.16 CDO72136.1 - 0.55 9.5 9.5 0.77 9.1 9.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Vfa1 PF08432.10 CDO72136.1 - 1 9.6 9.0 1.3 9.3 9.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TSA PF03249.13 CDO72136.1 - 1.3 7.7 4.0 1.5 7.5 4.0 1.0 1 0 0 1 1 1 0 Type specific antigen DUF4407 PF14362.6 CDO72136.1 - 2.3 7.5 9.5 3 7.1 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zn_clus PF00172.18 CDO72136.1 - 4.3 7.5 10.5 8.3 6.6 10.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain rve PF00665.26 CDO72137.1 - 1.3e-13 51.2 0.0 2.8e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO72137.1 - 2.2e-07 30.7 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ferrochelatase PF00762.19 CDO72137.1 - 0.039 13.0 0.4 5.2 6.0 0.1 2.4 2 1 1 3 3 3 0 Ferrochelatase betaPIX_CC PF16523.5 CDO72138.1 - 9.6 6.1 15.6 1.6 8.6 6.6 2.6 3 0 0 3 3 3 0 betaPIX coiled coil Transposase_21 PF02992.14 CDO72139.1 - 1.2e-19 70.4 0.0 2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 CDO72139.1 - 0.0044 16.3 1.3 0.0062 15.8 0.0 1.8 2 0 0 2 2 2 1 Plavaka transposase DUF1258 PF06869.12 CDO72139.1 - 0.0051 16.3 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Fez1 PF06818.15 CDO72140.1 - 0.69 10.3 4.8 3.5 8.0 1.4 2.1 1 1 1 2 2 2 0 Fez1 TMF_TATA_bd PF12325.8 CDO72140.1 - 7.4 6.8 7.6 1.1 9.5 2.3 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Flg_hook PF02120.16 CDO72144.1 - 0.46 10.4 2.5 9.1 6.3 0.1 2.6 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK ANAPC4_WD40 PF12894.7 CDO72145.1 - 1.6e-05 25.1 0.1 0.17 12.2 0.0 3.4 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDO72145.1 - 2.8e-05 24.8 5.0 0.028 15.3 0.0 5.8 6 1 0 6 6 6 1 WD domain, G-beta repeat eIF2A PF08662.11 CDO72145.1 - 0.0054 16.6 0.0 0.16 11.8 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF3681 PF12442.8 CDO72145.1 - 0.057 13.9 2.0 0.069 13.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Sad1_UNC PF07738.13 CDO72147.1 - 8e-22 77.7 0.0 2.4e-20 72.9 0.0 2.1 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF3467 PF11950.8 CDO72149.1 - 0.041 14.1 1.9 0.22 11.7 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3467) Myb_DNA-bind_3 PF12776.7 CDO72150.1 - 0.00025 22.0 0.0 0.00051 21.0 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO72150.1 - 0.002 18.5 0.5 0.0052 17.1 0.2 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 CDO72151.1 - 7e-18 64.8 0.0 8.7e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO72151.1 - 1.4e-05 24.9 0.0 3.4e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO72151.1 - 0.0044 16.6 0.0 0.0077 15.9 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO72151.1 - 0.031 14.6 0.1 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain TAXi_N PF14543.6 CDO72153.1 - 0.007 16.6 0.0 0.023 15.0 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Retrotran_gag_2 PF14223.6 CDO72155.1 - 6.9e-24 84.1 0.0 1.1e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO72155.1 - 4.7e-05 23.3 2.2 9.5e-05 22.3 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDO72155.1 - 0.012 15.4 3.2 0.02 14.7 3.2 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4219 PF13961.6 CDO72155.1 - 0.031 14.0 0.0 0.096 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC_3 PF13917.6 CDO72155.1 - 0.15 12.0 0.5 0.35 10.9 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 CDO72156.1 - 4e-10 39.5 0.1 8.4e-09 35.2 0.0 2.1 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO72157.1 - 2e-05 24.4 2.2 3.1e-05 23.8 2.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDO72157.1 - 0.0039 17.0 3.2 0.0065 16.3 3.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDO72157.1 - 0.11 12.5 0.5 0.11 12.5 0.5 1.6 2 0 0 2 2 2 0 Zinc knuckle SAM_2 PF07647.17 CDO72159.1 - 5.6e-09 36.0 0.0 1.4e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CDO72159.1 - 0.00012 22.4 0.0 0.00027 21.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 CDO72159.1 - 0.096 13.0 0.8 0.17 12.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) HET PF06985.11 CDO72160.1 - 2.3e-09 37.8 0.1 2.5e-05 24.7 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DIOX_N PF14226.6 CDO72161.1 - 4.5e-32 111.3 0.0 6.6e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO72161.1 - 5.1e-15 55.8 0.0 2.1e-14 53.8 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 CDO72162.1 - 1e-33 116.4 0.0 2.2e-33 115.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO72162.1 - 1.1e-23 84.1 0.0 5.1e-23 81.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO72162.1 - 1e-06 28.8 0.3 2e-06 27.8 0.3 1.4 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.27 CDO72162.1 - 0.086 13.4 0.6 0.18 12.4 0.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Dynamin_N PF00350.23 CDO72164.1 - 2.1e-20 73.4 0.1 4.6e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CDO72164.1 - 1.3e-13 51.0 0.0 4.8e-13 49.2 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDO72164.1 - 1.5e-07 31.2 0.7 3.3e-06 26.8 0.7 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDO72164.1 - 2.7e-05 24.1 1.1 0.15 11.9 0.4 2.7 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 CDO72164.1 - 0.0012 18.5 0.6 0.023 14.3 0.6 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.13 CDO72164.1 - 0.004 16.3 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 CDO72164.1 - 0.0053 17.0 0.0 2.3 8.4 0.0 3.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CDO72164.1 - 0.04 13.7 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.21 CDO72164.1 - 0.079 12.4 0.2 2.9 7.3 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family FeoB_N PF02421.18 CDO72164.1 - 0.11 12.0 0.1 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B TsaE PF02367.17 CDO72164.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ribosomal_L5_C PF00673.21 CDO72165.1 - 9.3e-27 93.0 0.0 1.5e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Lactamase_B PF00753.27 CDO72165.1 - 3.2e-11 43.6 0.3 6.8e-11 42.5 0.3 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDO72165.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Peptidase_M64 PF09471.10 CDO72166.1 - 6.8e-22 78.3 0.0 1.4e-09 37.9 0.0 2.6 2 1 0 2 2 2 2 IgA Peptidase M64 Pkinase PF00069.25 CDO72167.1 - 7.5e-72 241.8 0.0 1.2e-71 241.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO72167.1 - 6.4e-50 169.8 0.0 1.5e-49 168.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4704 PF15787.5 CDO72167.1 - 0.00063 19.1 1.7 0.092 12.0 0.2 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4704) Pkinase_fungal PF17667.1 CDO72167.1 - 0.0019 17.1 0.0 0.0019 17.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CDO72167.1 - 0.013 14.8 0.1 0.28 10.4 0.0 2.6 3 0 0 3 3 3 0 Kinase-like RICTOR_N PF14664.6 CDO72167.1 - 2 7.3 14.9 0.16 10.9 0.5 3.0 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term Ribosomal_L1 PF00687.21 CDO72168.1 - 1.9e-58 197.6 0.4 5.1e-58 196.2 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3361 PF11841.8 CDO72168.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) ADH_zinc_N PF00107.26 CDO72169.1 - 3.4e-31 107.9 0.1 5.2e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO72169.1 - 4.5e-20 73.1 0.0 1e-19 71.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO72169.1 - 4.3e-13 49.1 0.3 8.5e-11 41.7 0.0 2.9 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain LRR_4 PF12799.7 CDO72170.1 - 0.00034 20.9 8.1 3.6 8.1 0.1 6.0 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDO72170.1 - 1 9.6 0.0 1 9.6 0.0 3.8 6 0 0 6 6 6 0 Leucine Rich repeat MIF4G PF02854.19 CDO72171.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain COesterase PF00135.28 CDO72172.1 - 6.6e-89 299.1 0.0 9.7e-89 298.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDO72172.1 - 1.5e-05 25.0 0.3 8.6e-05 22.5 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 CDO72173.1 - 6.6e-17 61.5 43.3 5.5e-09 35.4 22.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily LRR_4 PF12799.7 CDO72174.1 - 0.0097 16.3 2.5 3.1 8.3 0.9 4.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDO72174.1 - 0.25 11.2 4.0 2.9 7.7 0.1 3.8 2 2 1 3 3 3 0 Leucine rich repeat DUF676 PF05057.14 CDO72176.1 - 0.0013 18.2 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CDO72176.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.4 1 1 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 CDO72176.1 - 0.23 11.1 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein AA_permease_2 PF13520.6 CDO72177.1 - 1.9e-52 178.6 40.5 2.3e-52 178.3 40.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDO72177.1 - 6.6e-12 44.8 40.2 1.3e-07 30.6 23.8 2.1 2 0 0 2 2 2 2 Amino acid permease DDE_3 PF13358.6 CDO72178.1 - 1.1e-08 35.0 0.1 0.0002 21.1 0.1 2.7 2 0 0 2 2 2 2 DDE superfamily endonuclease adh_short PF00106.25 CDO72179.1 - 6.6e-44 149.7 0.2 8.3e-44 149.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO72179.1 - 3.6e-37 128.2 0.1 4.6e-37 127.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO72179.1 - 1.3e-07 31.7 0.1 2e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CDO72179.1 - 0.002 17.6 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF3012 PF11216.8 CDO72179.1 - 0.016 15.2 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) F-box-like PF12937.7 CDO72181.1 - 0.0034 17.2 4.0 0.004 17.0 1.0 2.7 2 1 0 2 2 2 1 F-box-like ELFV_dehydrog PF00208.21 CDO72182.1 - 9.6e-55 185.9 0.0 1.3e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CDO72182.1 - 4.4e-19 67.6 0.0 5.6e-14 50.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase HET PF06985.11 CDO72183.1 - 3.8e-09 37.1 0.3 1.9e-06 28.3 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_20 PF00728.22 CDO72185.1 - 2e-78 264.3 0.2 4.4e-76 256.6 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CDO72185.1 - 1.5e-17 64.5 0.0 2.8e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CDO72185.1 - 4.1e-07 30.8 0.1 1.2e-06 29.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 DUF3450 PF11932.8 CDO72186.1 - 0.002 17.5 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TPR_12 PF13424.6 CDO72186.1 - 0.043 14.1 0.6 0.19 12.1 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Cbl_N PF02262.16 CDO72186.1 - 0.095 12.7 0.1 0.31 11.0 0.0 2.0 2 1 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Glyco_hydro_20 PF00728.22 CDO72187.1 - 6e-90 302.2 0.0 7e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Cellulase PF00150.18 CDO72187.1 - 0.012 15.0 0.1 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) ENTH PF01417.20 CDO72188.1 - 1.2e-45 154.6 0.1 1.8e-45 154.0 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CDO72188.1 - 0.00014 20.9 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 CDO72188.1 - 0.036 13.9 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 VHS domain DUF4515 PF14988.6 CDO72189.1 - 0.00063 19.6 1.0 0.0007 19.5 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) BLOC1_2 PF10046.9 CDO72189.1 - 0.0011 19.2 0.2 0.0069 16.7 0.1 2.1 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CdvA PF18822.1 CDO72189.1 - 0.003 17.4 1.3 0.027 14.3 0.4 2.2 2 0 0 2 2 2 1 CdvA-like coiled-coil domain DUF1664 PF07889.12 CDO72189.1 - 0.0039 17.2 0.1 0.0069 16.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 CDO72189.1 - 0.0097 16.3 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein SKA1 PF07160.12 CDO72189.1 - 0.035 14.0 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Myosin_tail_1 PF01576.19 CDO72189.1 - 0.044 11.6 0.1 0.064 11.1 0.1 1.1 1 0 0 1 1 1 0 Myosin tail KxDL PF10241.9 CDO72189.1 - 0.055 13.7 1.0 2 8.8 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein CCDC53 PF10152.9 CDO72189.1 - 0.058 13.8 4.0 0.23 11.8 4.0 2.1 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF16 PF01519.16 CDO72189.1 - 0.061 13.8 0.1 0.13 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 RmuC PF02646.16 CDO72189.1 - 0.062 12.4 0.6 0.086 12.0 0.1 1.4 2 0 0 2 2 2 0 RmuC family Spectrin PF00435.21 CDO72189.1 - 0.071 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Spectrin repeat DUF1202 PF06717.11 CDO72189.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) DUF4164 PF13747.6 CDO72189.1 - 0.11 12.8 0.4 0.21 11.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) TMF_DNA_bd PF12329.8 CDO72189.1 - 0.12 12.4 0.7 0.22 11.5 0.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 CDO72189.1 - 0.15 10.9 0.2 0.24 10.2 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Ntox28 PF15605.6 CDO72189.1 - 0.23 11.7 0.9 0.29 11.4 0.1 1.6 2 0 0 2 2 1 0 Bacterial toxin 28 Baculo_PEP_C PF04513.12 CDO72189.1 - 0.24 11.4 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 CDO72189.1 - 0.28 11.6 3.1 0.2 12.1 0.5 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 CDO72189.1 - 0.36 10.9 1.1 0.77 9.8 0.1 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 CDO72189.1 - 0.39 11.1 3.1 1.4 9.4 0.7 2.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 CDO72189.1 - 0.4 10.6 2.3 0.48 10.4 0.4 1.9 2 1 0 2 2 2 0 Prefoldin subunit Mito_fiss_reg PF05308.11 CDO72189.1 - 2.3 8.3 8.8 0.11 12.5 3.2 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator PTCRA PF15028.6 CDO72190.1 - 0.48 10.1 5.9 1.2 8.8 0.2 3.3 3 0 0 3 3 3 0 Pre-T-cell antigen receptor RNA_pol_Rpb4 PF03874.16 CDO72191.1 - 2.9e-22 79.3 0.3 2.9e-22 79.3 0.3 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 p25-alpha PF05517.12 CDO72191.1 - 0.023 14.9 0.3 0.036 14.2 0.3 1.3 1 0 0 1 1 1 0 p25-alpha Miga PF10265.9 CDO72191.1 - 0.12 11.3 0.5 0.13 11.2 0.5 1.1 1 0 0 1 1 1 0 Mitoguardin Nnf1 PF03980.14 CDO72191.1 - 0.71 10.3 3.8 0.41 11.0 1.5 1.7 2 0 0 2 2 2 0 Nnf1 NOT2_3_5 PF04153.18 CDO72192.1 - 7.6e-32 110.2 0.6 7.6e-32 110.2 0.6 2.2 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family COesterase PF00135.28 CDO72193.1 - 8.5e-61 206.4 0.0 5.2e-37 127.9 0.0 3.0 2 1 0 2 2 2 2 Carboxylesterase family Hydantoinase_B PF02538.14 CDO72193.1 - 0.17 10.3 0.0 0.28 9.6 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase TrkH PF02386.16 CDO72194.1 - 6.7e-76 255.7 2.5 1.4e-56 192.0 0.1 2.0 2 0 0 2 2 2 2 Cation transport protein WD40 PF00400.32 CDO72195.1 - 0.00013 22.6 0.2 1.7 9.6 0.0 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_2 PF13360.6 CDO72195.1 - 0.096 12.2 0.6 8.4 5.9 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain ANAPC4_WD40 PF12894.7 CDO72195.1 - 0.15 12.4 0.1 7.4 7.0 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 CDO72197.1 - 2.4e-39 134.8 0.0 4.2e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDO72197.1 - 2e-10 40.3 0.0 5.2e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CDO72197.1 - 6.2e-07 29.3 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDO72197.1 - 2.8e-05 24.6 0.1 0.00096 19.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CDO72197.1 - 3.8e-05 23.9 0.0 6.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 CDO72197.1 - 4.9e-05 23.4 0.0 9.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CDO72197.1 - 8.9e-05 22.5 0.5 0.0013 18.7 0.5 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDO72197.1 - 0.0001 22.6 0.1 0.003 17.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 CDO72197.1 - 0.00018 22.1 0.0 0.00037 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CDO72197.1 - 0.00036 20.5 0.1 0.00097 19.1 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 CDO72197.1 - 0.00036 20.0 0.2 0.0019 17.6 0.2 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CDO72197.1 - 0.00045 20.4 0.0 0.00077 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CDO72197.1 - 0.00055 20.2 0.1 0.0038 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDO72197.1 - 0.00059 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 CDO72197.1 - 0.003 17.0 0.1 1.8 8.0 0.0 2.8 2 1 1 3 3 3 1 Bacterial TniB protein RNA_helicase PF00910.22 CDO72197.1 - 0.0035 17.7 0.0 0.0072 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 CDO72197.1 - 0.0043 16.3 0.1 0.0069 15.6 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 CDO72197.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 CDO72197.1 - 0.011 15.3 0.2 0.043 13.3 0.0 2.1 2 1 0 2 2 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CDO72197.1 - 0.012 14.9 0.1 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 CDO72197.1 - 0.012 15.2 0.2 0.16 11.5 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CDO72197.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CDO72197.1 - 0.017 14.9 0.1 0.028 14.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDO72197.1 - 0.02 15.4 0.0 0.066 13.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 CDO72197.1 - 0.021 14.8 0.1 0.046 13.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 CDO72197.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 CDO72197.1 - 0.032 14.2 0.0 0.087 12.8 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 CDO72197.1 - 0.044 13.1 0.0 1.6 8.0 0.0 2.8 2 1 1 3 3 3 0 KaiC Hydin_ADK PF17213.3 CDO72197.1 - 0.048 13.9 0.1 0.5 10.6 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Sigma54_activat PF00158.26 CDO72197.1 - 0.065 12.9 0.0 0.23 11.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 CDO72197.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 CDO72197.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 tRNA_lig_kinase PF08303.11 CDO72197.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain SKI PF01202.22 CDO72197.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase ATPase_2 PF01637.18 CDO72197.1 - 0.15 12.0 0.0 0.8 9.6 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 CDO72197.1 - 0.17 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 CDO72197.1 - 0.18 10.9 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 CDO72197.1 - 0.19 11.4 0.0 0.8 9.4 0.0 2.1 3 0 0 3 3 2 0 Guanylate kinase Transposase_21 PF02992.14 CDO72198.1 - 5.6e-12 45.4 0.0 4.1e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 DUF2457 PF10446.9 CDO72198.1 - 0.0016 17.7 8.5 0.0027 16.9 8.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) DUF1258 PF06869.12 CDO72198.1 - 0.03 13.8 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DUF4218 PF13960.6 CDO72198.1 - 0.083 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) RXT2_N PF08595.11 CDO72198.1 - 1 9.4 6.2 11 6.1 5.0 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal FYDLN_acid PF09538.10 CDO72198.1 - 1.1 10.0 13.3 0.32 11.7 9.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Astro_capsid_p PF12226.8 CDO72198.1 - 7.5 5.6 6.4 12 4.9 6.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein LEA_6 PF10714.9 CDO72199.1 - 0.06 13.4 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 RT_RNaseH PF17917.1 CDO72200.1 - 1.5e-38 131.2 0.1 2.7e-38 130.4 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO72200.1 - 5.4e-36 122.6 0.0 9.5e-36 121.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO72200.1 - 5.8e-29 101.2 0.1 9.3e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDO72200.1 - 3.7e-20 71.8 0.7 7.4e-20 70.8 0.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO72200.1 - 3.6e-14 53.0 0.0 1.2e-13 51.3 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 CDO72200.1 - 9.5e-05 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDO72200.1 - 0.0003 21.4 0.0 0.00058 20.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 CDO72200.1 - 0.00071 19.7 0.0 0.0019 18.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 CDO72200.1 - 0.0049 16.8 0.5 0.0049 16.8 0.5 2.3 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 CDO72200.1 - 0.011 16.3 0.0 0.023 15.3 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4726 PF15855.5 CDO72200.1 - 0.015 15.5 1.4 0.05 13.8 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) DUF4129 PF13559.6 CDO72200.1 - 0.35 11.2 4.7 0.45 10.8 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Retrotrans_gag PF03732.17 CDO72201.1 - 5e-07 29.9 3.5 8.1e-07 29.2 0.1 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 CDO72201.1 - 1.3e-06 28.2 2.3 2.5e-06 27.3 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle Apolipoprotein PF01442.18 CDO72201.1 - 0.004 17.1 4.0 0.0099 15.8 4.0 1.6 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2890 PF11081.8 CDO72201.1 - 0.016 15.4 0.9 0.038 14.1 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF1192 PF06698.11 CDO72201.1 - 0.043 13.9 4.1 0.06 13.4 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4407 PF14362.6 CDO72201.1 - 0.12 11.7 0.7 0.21 10.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TRCF PF03461.15 CDO72201.1 - 0.13 12.7 0.2 0.54 10.7 0.0 2.1 2 1 1 3 3 3 0 TRCF domain OmpH PF03938.14 CDO72201.1 - 0.17 12.2 1.8 0.3 11.4 1.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RecX PF02631.16 CDO72201.1 - 0.2 12.1 4.6 0.26 11.7 0.1 2.2 2 0 0 2 2 2 0 RecX family zf-CCHC_5 PF14787.6 CDO72201.1 - 0.22 11.3 2.8 0.43 10.3 2.8 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 CDO72201.1 - 0.24 11.2 1.1 0.42 10.4 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 CDO72201.1 - 0.44 10.4 2.6 0.7 9.8 2.6 1.3 1 0 0 1 1 1 0 Zinc knuckle GvpL_GvpF PF06386.11 CDO72201.1 - 0.67 9.8 5.2 0.14 12.1 1.3 1.7 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF5549 PF17703.1 CDO72201.1 - 1.9 8.1 8.4 0.14 11.8 3.5 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5549) DUF4404 PF14357.6 CDO72201.1 - 3.9 8.2 8.1 3.2 8.5 6.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Asp PF00026.23 CDO72202.1 - 4e-21 75.8 0.0 6.4e-21 75.1 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Metallophos PF00149.28 CDO72203.1 - 5e-10 40.2 0.0 7.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDO72203.1 - 1.5e-05 25.3 0.0 0.00079 19.7 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TetR_C_33 PF13305.6 CDO72203.1 - 0.038 14.7 0.2 0.096 13.4 0.1 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Trehalase PF01204.18 CDO72204.1 - 6.3e-96 322.2 0.1 8.7e-84 282.2 0.0 2.4 2 1 0 2 2 2 2 Trehalase GDE_C PF06202.14 CDO72204.1 - 0.0064 15.5 0.0 0.025 13.5 0.0 1.8 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase RRM_1 PF00076.22 CDO72205.1 - 1.7e-08 34.2 0.0 4.4e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 CDO72205.1 - 2.5e-08 34.1 0.1 5.4e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 PWI domain Hydin_ADK PF17213.3 CDO72205.1 - 9.8 6.4 6.0 0.71 10.1 0.8 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain ATP-synt_C PF00137.21 CDO72207.1 - 1.8e-32 111.4 34.5 1.1e-20 73.7 15.4 2.4 2 0 0 2 2 2 2 ATP synthase subunit C Sad1_UNC PF07738.13 CDO72207.1 - 3e-28 98.5 0.0 5.3e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal p450 PF00067.22 CDO72208.1 - 9.2e-78 262.0 0.0 1.3e-77 261.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 CDO72208.1 - 2.7e-30 105.6 0.0 4.3e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CDO72208.1 - 4.9e-25 88.4 0.0 9.6e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CDO72208.1 - 4.4e-10 40.2 0.0 9.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.11 CDO72208.1 - 0.0012 19.0 0.0 0.0034 17.5 0.0 1.8 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_5 PF12724.7 CDO72208.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_3 PF12641.7 CDO72208.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain p450 PF00067.22 CDO72209.1 - 2.7e-77 260.5 0.0 3.3e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ALG11_N PF15924.5 CDO72210.1 - 1.4e-90 303.0 0.2 1.9e-90 302.5 0.2 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CDO72210.1 - 1.4e-25 89.8 0.0 2.8e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDO72210.1 - 3.5e-12 46.9 0.0 1e-11 45.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CDO72210.1 - 0.0001 22.4 0.0 0.00021 21.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_20 PF00982.21 CDO72210.1 - 0.00061 18.6 0.0 0.00096 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_2 PF13524.6 CDO72210.1 - 0.0058 17.0 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ABC_transp_aux PF09822.9 CDO72210.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Tetraspanin PF00335.20 CDO72212.1 - 9.6e-10 38.6 5.2 1.4e-09 38.0 5.2 1.2 1 0 0 1 1 1 1 Tetraspanin family Pyr_redox_2 PF07992.14 CDO72213.1 - 1.2e-38 133.0 0.0 1.1e-18 67.5 0.0 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDO72213.1 - 9.1e-10 39.0 0.5 6.6e-07 29.8 0.0 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDO72213.1 - 7.1e-08 32.0 0.1 0.0039 16.5 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO72213.1 - 7.9e-06 25.3 0.0 5.7e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 CDO72213.1 - 1.6e-05 24.2 1.5 0.0026 16.9 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 CDO72213.1 - 3.5e-05 23.6 0.0 0.00011 21.9 0.0 1.6 1 1 1 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 CDO72213.1 - 3.9e-05 22.9 1.1 0.0047 16.1 0.1 3.1 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 CDO72213.1 - 0.0012 18.3 0.1 0.0074 15.7 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDO72213.1 - 0.0015 18.7 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CDO72213.1 - 0.018 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 CDO72213.1 - 0.019 13.7 0.4 0.043 12.5 0.4 1.6 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 CDO72213.1 - 0.024 13.5 0.0 0.052 12.4 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 CDO72213.1 - 0.084 12.5 0.3 18 4.9 0.1 3.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA FMN_dh PF01070.18 CDO72214.1 - 7.6e-110 367.2 0.0 9.3e-110 366.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CDO72214.1 - 0.00021 20.4 0.2 0.00066 18.8 0.2 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 CDO72214.1 - 0.002 17.5 0.0 1.9 7.7 0.0 2.5 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 CDO72214.1 - 0.032 13.4 0.2 0.047 12.8 0.2 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase FMN_dh PF01070.18 CDO72216.1 - 1.2e-91 307.4 0.0 1.5e-91 307.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CDO72216.1 - 0.0016 17.5 0.1 0.0033 16.5 0.1 1.4 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CDO72216.1 - 0.011 14.8 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase ThiG PF05690.14 CDO72216.1 - 0.13 11.6 2.2 12 5.1 0.0 3.1 3 1 1 4 4 4 0 Thiazole biosynthesis protein ThiG Dimer_Tnp_hAT PF05699.14 CDO72217.1 - 9.2e-15 54.2 0.0 1.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Plavaka PF18759.1 CDO72219.1 - 3.4e-112 374.9 0.0 4.6e-112 374.4 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase CHDCT2 PF08074.11 CDO72219.1 - 0.00023 21.4 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain Plavaka PF18759.1 CDO72220.1 - 3.9e-42 144.6 0.9 1.5e-20 73.7 0.0 2.3 1 1 1 2 2 2 2 Plavaka transposase Rhomboid_SP PF12595.8 CDO72220.1 - 0.028 13.8 1.0 0.34 10.2 0.2 2.2 2 0 0 2 2 2 0 Rhomboid serine protease PolyA_pol_arg_C PF12626.7 CDO72220.1 - 0.057 13.5 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus DNA_pol_phi PF04931.13 CDO72220.1 - 0.23 9.5 6.9 0.34 8.9 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mucin PF01456.17 CDO72223.1 - 2.7 8.0 16.1 3.3 7.7 16.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein NFACT-R_1 PF05670.13 CDO72224.1 - 3.2e-42 143.6 0.1 6.6e-42 142.6 0.0 1.5 2 0 0 2 2 2 1 NFACT protein RNA binding domain p450 PF00067.22 CDO72225.1 - 3.7e-60 204.0 0.0 1.6e-59 201.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.23 CDO72226.1 - 2.2e-81 273.7 6.2 2.6e-81 273.5 6.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO72226.1 - 5.3e-14 52.9 10.5 1.4e-11 45.0 5.9 3.4 2 2 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO72226.1 - 1.2e-05 25.8 0.1 0.33 11.6 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CDO72226.1 - 0.0041 17.6 0.0 0.89 10.2 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CDO72226.1 - 0.029 14.2 0.0 0.53 10.1 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DIOX_N PF14226.6 CDO72227.1 - 4.7e-29 101.5 0.0 7.6e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO72227.1 - 1.2e-05 25.7 0.2 0.0042 17.6 0.1 2.4 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily Methyltransf_25 PF13649.6 CDO72229.1 - 4.6e-11 43.3 0.1 1.8e-10 41.4 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 CDO72229.1 - 7.7e-11 41.9 0.1 1.6e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CDO72229.1 - 5.7e-09 36.5 0.4 3.3e-08 34.0 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO72229.1 - 5.8e-08 32.7 0.1 1.5e-07 31.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO72229.1 - 4.5e-07 29.9 0.0 6e-06 26.2 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CDO72229.1 - 3.6e-05 23.4 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CDO72229.1 - 9e-05 23.2 0.2 0.00026 21.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain TehB PF03848.14 CDO72229.1 - 0.00021 20.8 0.0 0.00036 20.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 CDO72229.1 - 0.00057 19.8 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CDO72229.1 - 0.0047 16.7 0.2 0.0076 16.0 0.2 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.6 CDO72229.1 - 0.013 16.5 0.0 0.033 15.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 CDO72229.1 - 0.017 14.1 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Vps51 PF08700.11 CDO72229.1 - 0.021 14.9 0.4 0.053 13.6 0.4 1.6 1 0 0 1 1 1 0 Vps51/Vps67 CMAS PF02353.20 CDO72229.1 - 0.034 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 CDO72229.1 - 0.065 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRMT5 PF05185.16 CDO72229.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_2 PF00891.18 CDO72229.1 - 0.14 11.5 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 CDO72229.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RPAP1_C PF08620.10 CDO72230.1 - 3.3e-20 72.0 0.2 6.6e-20 71.0 0.2 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CDO72230.1 - 7.6e-11 41.6 6.2 7.6e-11 41.6 6.2 2.0 3 0 0 3 3 3 1 RPAP1-like, N-terminal Remorin_C PF03763.13 CDO72230.1 - 0.067 13.1 2.3 0.14 12.0 2.3 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region DMAP_binding PF06464.11 CDO72230.1 - 0.14 13.0 0.0 0.38 11.6 0.0 1.7 1 0 0 1 1 1 0 DMAP1-binding Domain Metal_resist PF13801.6 CDO72230.1 - 1.9 8.7 7.5 12 6.1 0.2 2.7 2 0 0 2 2 2 0 Heavy-metal resistance GH131_N PF18271.1 CDO72232.1 - 4.4e-90 301.8 0.0 6.2e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Pro-kuma_activ PF09286.11 CDO72232.1 - 1.9e-44 151.4 0.0 4.1e-44 150.3 0.0 1.5 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO72232.1 - 0.00025 20.4 0.3 0.00049 19.5 0.3 1.4 1 0 0 1 1 1 1 Subtilase family SWI-SNF_Ssr4 PF08549.10 CDO72233.1 - 1.8e-17 63.3 1.5 3.1e-09 36.1 0.0 3.0 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1750) DUF1192 PF06698.11 CDO72233.1 - 0.0033 17.5 0.3 0.0065 16.5 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) CLZ PF16526.5 CDO72233.1 - 0.088 13.2 0.3 0.088 13.2 0.3 1.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HIT PF01230.23 CDO72234.1 - 8e-25 87.4 0.1 1.3e-24 86.8 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CDO72234.1 - 1.9e-10 41.2 0.5 3e-10 40.6 0.3 1.5 1 1 1 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CDO72234.1 - 6.5e-05 22.8 0.2 0.00011 22.0 0.2 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pkinase PF00069.25 CDO72235.1 - 1.1e-40 139.7 0.0 8.8e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO72235.1 - 3e-27 95.5 0.0 2.7e-23 82.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Seadorna_VP7 PF07387.11 CDO72235.1 - 0.017 14.2 0.1 0.025 13.6 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 CDO72235.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CDO72235.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CDO72235.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDO72235.1 - 0.14 11.1 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CDO72235.1 - 0.18 11.1 0.0 5.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like p450 PF00067.22 CDO72236.1 - 4.7e-35 121.2 0.0 1.5e-33 116.3 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 zf-H2C2_5 PF13909.6 CDO72237.1 - 3.1e-05 23.6 1.8 0.00062 19.5 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CDO72237.1 - 0.0012 19.5 3.4 1.1 10.3 0.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 CDO72237.1 - 0.0068 16.4 1.4 0.24 11.5 0.1 2.4 2 0 0 2 2 2 1 BED zinc finger zf-Di19 PF05605.12 CDO72237.1 - 0.038 14.3 0.8 1.3 9.3 0.6 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CDO72237.1 - 1.1 9.9 7.8 6.3 7.5 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Aldo_ket_red PF00248.21 CDO72238.1 - 2.5e-39 135.2 0.0 1.8e-38 132.5 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Pyr_redox_2 PF07992.14 CDO72240.1 - 7.7e-39 133.7 0.2 9.9e-39 133.3 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDO72240.1 - 3e-13 50.1 0.1 2.4e-10 40.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDO72240.1 - 3.7e-09 36.3 0.2 1.1e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO72240.1 - 8.7e-08 32.3 0.7 0.011 15.8 0.1 3.9 3 1 1 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 CDO72240.1 - 1.7e-07 30.4 0.7 0.0079 15.1 0.0 2.4 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 CDO72240.1 - 2.6e-07 30.5 5.8 0.033 13.8 0.2 4.0 2 2 2 4 4 4 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CDO72240.1 - 0.00059 19.0 0.1 0.72 8.8 0.0 3.0 3 1 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 CDO72240.1 - 0.00068 18.4 0.2 3.5 6.2 0.0 3.8 4 0 0 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.6 CDO72240.1 - 0.00085 19.7 0.0 0.11 12.9 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding GIDA PF01134.22 CDO72240.1 - 0.001 18.2 4.6 7.6 5.5 0.1 4.4 3 1 2 5 5 5 1 Glucose inhibited division protein A K_oxygenase PF13434.6 CDO72240.1 - 0.0024 17.1 0.0 0.68 9.0 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CDO72240.1 - 0.0027 17.9 0.1 0.49 10.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 CDO72240.1 - 0.0049 17.1 0.1 4.6 7.5 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain StbA PF06406.11 CDO72240.1 - 0.044 13.0 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 StbA protein DUF1188 PF06690.11 CDO72240.1 - 0.05 13.1 0.0 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) AlaDh_PNT_C PF01262.21 CDO72240.1 - 0.1 11.9 0.3 8.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CDO72240.1 - 0.12 11.6 0.0 9.8 5.3 0.0 2.2 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 CDO72240.1 - 0.16 11.2 0.6 6.1 6.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain RNase_H PF00075.24 CDO72241.1 - 1e-07 32.3 0.0 2.5e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO72241.1 - 5.2e-06 27.1 0.0 9.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Proteasome PF00227.26 CDO72242.1 - 2.3e-24 85.9 0.0 4.8e-24 84.9 0.0 1.7 1 1 0 1 1 1 1 Proteasome subunit adh_short PF00106.25 CDO72243.1 - 8.5e-14 51.5 0.2 4.9e-09 35.9 0.1 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 CDO72243.1 - 4.9e-11 42.6 0.0 5.2e-10 39.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Helicase_C PF00271.31 CDO72245.1 - 5.4e-12 46.0 0.0 1.2e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PuR_N PF09182.10 CDO72246.1 - 0.054 13.4 0.1 0.2 11.6 0.1 2.0 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal Sugar_tr PF00083.24 CDO72247.1 - 7.4e-103 344.8 22.4 9.2e-103 344.5 22.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO72247.1 - 2.3e-17 63.0 35.4 2.3e-17 63.0 35.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 CDO72247.1 - 0.025 15.1 0.5 0.044 14.3 0.5 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Con-6 PF10346.9 CDO72249.1 - 4.5e-33 113.0 4.6 6.1e-16 58.2 0.7 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Adeno_hexon_C PF03678.14 CDO72249.1 - 0.044 13.2 0.0 0.049 13.1 0.0 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, C-terminal domain LacI PF00356.21 CDO72249.1 - 0.079 12.8 0.8 2 8.2 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family ERCC4 PF02732.15 CDO72250.1 - 1.8e-21 77.0 0.0 3.4e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain zf-C2H2_4 PF13894.6 CDO72252.1 - 0.52 11.3 11.9 2.6 9.1 0.6 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger Rot1 PF10681.9 CDO72253.1 - 2.8e-51 174.0 0.1 3.2e-51 173.8 0.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Glycos_transf_3 PF00591.21 CDO72254.1 - 4.3e-09 36.3 1.0 6.5e-09 35.8 1.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 CDO72254.1 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Glycos_transf_3 PF00591.21 CDO72255.1 - 4.6e-14 52.6 2.7 6.5e-14 52.1 2.7 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 CDO72255.1 - 4.4e-06 26.4 0.0 6.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain adh_short PF00106.25 CDO72258.1 - 3.3e-27 95.2 0.0 1.4e-24 86.6 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO72258.1 - 2.8e-17 63.1 0.0 2.1e-16 60.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO72258.1 - 8.6e-09 35.5 0.0 1.3e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO72258.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CDO72258.1 - 0.0041 17.4 0.2 0.01 16.1 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CDO72258.1 - 0.1 13.1 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Clat_adaptor_s PF01217.20 CDO72259.1 - 7.4e-57 191.3 2.9 8.1e-57 191.1 2.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Gpi16 PF04113.14 CDO72260.1 - 1.8e-97 327.1 0.3 3.3e-52 177.7 0.2 2.9 1 1 1 2 2 2 2 Gpi16 subunit, GPI transamidase component AAA PF00004.29 CDO72261.1 - 3e-87 289.8 0.0 1.8e-42 144.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDO72261.1 - 4.4e-23 80.8 0.2 2.1e-12 46.7 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 CDO72261.1 - 8.2e-13 48.5 0.0 3.2e-07 30.4 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CDO72261.1 - 1.6e-12 48.2 2.0 4.1e-05 24.0 0.1 4.1 2 2 2 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 CDO72261.1 - 5.7e-12 45.7 0.0 0.00034 20.4 0.0 3.6 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CDO72261.1 - 8.9e-09 35.7 0.0 0.0015 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDO72261.1 - 1.4e-07 31.9 0.1 0.0034 17.6 0.0 4.1 2 2 2 4 4 4 1 AAA domain AAA_33 PF13671.6 CDO72261.1 - 1.7e-07 31.5 0.0 0.00036 20.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CDO72261.1 - 4.7e-06 26.5 0.0 0.001 18.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 CDO72261.1 - 1.2e-05 24.7 0.0 0.011 15.0 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain TsaE PF02367.17 CDO72261.1 - 1.7e-05 24.8 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CDO72261.1 - 2.9e-05 24.1 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CDO72261.1 - 0.0001 22.2 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDO72261.1 - 0.00027 21.3 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 CDO72261.1 - 0.00031 20.7 0.0 0.072 13.0 0.0 3.8 2 2 0 3 3 3 1 NACHT domain AAA_7 PF12775.7 CDO72261.1 - 0.00039 20.0 0.0 0.26 10.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 CDO72261.1 - 0.00081 18.8 0.2 0.31 10.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CDO72261.1 - 0.0011 19.2 0.0 0.091 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 CDO72261.1 - 0.0021 18.0 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CDO72261.1 - 0.0022 18.0 0.0 0.11 12.4 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 CDO72261.1 - 0.0024 18.4 0.0 0.0087 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CDO72261.1 - 0.0032 17.1 1.4 1.5 8.3 0.1 3.8 2 2 2 4 4 4 1 AAA domain Bac_DnaA PF00308.18 CDO72261.1 - 0.0036 17.2 0.0 0.69 9.7 0.0 3.4 4 0 0 4 4 4 1 Bacterial dnaA protein Zeta_toxin PF06414.12 CDO72261.1 - 0.0054 16.0 0.0 0.066 12.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 CDO72261.1 - 0.018 14.8 0.1 0.21 11.3 0.0 2.5 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.18 CDO72261.1 - 0.021 14.6 0.0 0.83 9.3 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CDO72261.1 - 0.022 13.9 0.0 3.7 6.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 CDO72261.1 - 0.023 14.4 0.0 0.67 9.6 0.0 2.9 2 1 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 CDO72261.1 - 0.024 15.1 0.0 0.44 11.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 CDO72261.1 - 0.043 13.6 0.0 0.33 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 CDO72261.1 - 0.043 13.0 0.0 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATPase PF06745.13 CDO72261.1 - 0.047 13.0 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 CDO72261.1 - 0.049 13.1 0.0 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 CDO72261.1 - 0.053 13.8 0.0 0.95 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 CDO72261.1 - 0.1 11.5 0.0 0.88 8.4 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Parvo_NS1 PF01057.17 CDO72261.1 - 0.12 11.5 0.0 0.29 10.2 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 CDO72261.1 - 0.13 12.4 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain adh_short_C2 PF13561.6 CDO72262.1 - 1.6e-43 148.9 0.0 2.2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO72262.1 - 1.2e-35 122.7 0.0 3e-35 121.5 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO72262.1 - 4e-07 30.1 0.0 8.6e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 KR domain Coprogen_oxidas PF01218.18 CDO72263.1 - 1.9e-132 440.5 0.0 2.1e-132 440.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase T6SS_VasE PF05936.12 CDO72263.1 - 0.1 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Antimicrobial_5 PF08026.11 CDO72264.1 - 0.087 12.9 0.6 0.21 11.7 0.6 1.6 1 0 0 1 1 1 0 Bee antimicrobial peptide Lactamase_B PF00753.27 CDO72265.1 - 1.2e-08 35.2 1.7 2.4e-08 34.2 1.7 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDO72265.1 - 0.021 14.4 0.2 0.04 13.4 0.1 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain ArfGap PF01412.18 CDO72266.1 - 4.8e-14 52.4 0.1 1e-13 51.4 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Glyco_hydro_12 PF01670.16 CDO72267.1 - 2.6e-38 132.2 13.5 6.2e-38 130.9 13.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 DUF5560 PF17715.1 CDO72267.1 - 0.39 10.1 2.5 9.1 5.7 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5560) Glyco_hydro_12 PF01670.16 CDO72268.1 - 2.3e-32 112.7 11.5 3.2e-32 112.2 11.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DEC-1_N PF04625.13 CDO72268.1 - 0.14 11.2 2.2 0.19 10.7 2.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DDE_3 PF13358.6 CDO72269.1 - 5.1e-14 52.3 0.0 8e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CDO72269.1 - 4.7e-07 30.0 0.5 5.5e-05 23.3 0.1 2.8 2 0 0 2 2 2 1 Transposase Sigma70_r4 PF04545.16 CDO72269.1 - 0.00048 19.6 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 CDO72269.1 - 0.00085 19.1 0.1 0.0062 16.3 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CDO72269.1 - 0.0012 18.9 0.0 0.0041 17.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 CDO72269.1 - 0.0018 18.0 0.2 0.0054 16.5 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 CDO72269.1 - 0.0094 15.9 0.0 0.045 13.7 0.0 2.2 2 0 0 2 2 2 1 HTH domain GntR PF00392.21 CDO72269.1 - 0.021 14.5 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_IclR PF09339.10 CDO72269.1 - 0.025 14.4 0.2 0.081 12.7 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain UPF0122 PF04297.14 CDO72269.1 - 0.079 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_Crp_2 PF13545.6 CDO72269.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_AraC PF00165.23 CDO72269.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Acetyltransf_1 PF00583.25 CDO72270.1 - 8.4e-13 48.6 0.0 9.4e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDO72270.1 - 4.7e-11 42.7 0.0 5.1e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDO72270.1 - 1.9e-08 34.6 0.0 2.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDO72270.1 - 0.0052 16.9 0.0 0.0085 16.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase UQ_con PF00179.26 CDO72271.1 - 1.9e-43 147.5 0.0 2.3e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 CDO72271.1 - 2.2e-20 72.2 0.4 3.8e-20 71.5 0.4 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 CDO72271.1 - 0.0015 18.2 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B FeoA PF04023.14 CDO72271.1 - 0.15 12.3 0.2 0.28 11.5 0.2 1.3 1 0 0 1 1 1 0 FeoA domain TPP_enzyme_N PF02776.18 CDO72272.1 - 1.8e-36 125.4 1.1 3.6e-33 114.6 0.4 2.7 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CDO72272.1 - 4.1e-16 59.1 1.3 8.4e-16 58.1 0.1 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CDO72272.1 - 1.8e-07 30.9 0.1 6e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 CDO72273.1 - 2.9e-23 82.4 3.5 1.1e-20 74.0 1.7 3.1 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CDO72273.1 - 1.1e-19 70.7 0.0 1.9e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CDO72273.1 - 1e-12 48.0 0.0 1.4e-11 44.2 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Rick_17kDa_Anti PF05433.15 CDO72273.1 - 0.0015 18.3 3.9 0.0027 17.5 0.9 2.5 2 0 0 2 2 2 1 Glycine zipper 2TM domain DXP_synthase_N PF13292.6 CDO72273.1 - 0.12 11.5 0.4 0.28 10.3 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Gly-zipper_Omp PF13488.6 CDO72273.1 - 0.21 11.6 9.2 0.44 10.6 3.9 2.6 2 0 0 2 2 2 0 Glycine zipper DNA_ligase_A_C PF04679.15 CDO72274.1 - 0.0058 17.2 0.0 1.7 9.3 0.0 3.3 2 1 0 2 2 2 1 ATP dependent DNA ligase C terminal region adh_short PF00106.25 CDO72275.1 - 6.9e-39 133.3 0.0 9.3e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO72275.1 - 1.7e-29 103.1 0.0 2.1e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO72275.1 - 5.9e-10 39.3 0.0 1.1e-09 38.5 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO72275.1 - 0.0011 18.5 0.1 0.0042 16.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CDO72275.1 - 0.0015 18.5 0.6 0.003 17.5 0.6 1.7 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CDO72275.1 - 0.0062 15.7 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 CDO72276.1 - 1.1e-32 113.1 0.0 1.5e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO72276.1 - 2.2e-26 92.9 0.0 2.8e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO72276.1 - 8.1e-10 38.9 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDO72276.1 - 3.9e-05 23.6 0.2 5.6e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF4232 PF14016.6 CDO72276.1 - 0.084 13.0 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) PriCT_1 PF08708.11 CDO72276.1 - 0.25 11.1 0.8 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) Glyco_hydro_35 PF01301.19 CDO72277.1 - 7.8e-61 206.4 0.0 1.9e-59 201.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 CDO72277.1 - 1.7e-57 193.0 1.8 1.6e-31 109.2 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 CDO72277.1 - 4.6e-36 124.3 0.9 7.8e-36 123.6 0.9 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 CDO72277.1 - 1.4e-18 66.2 0.0 4.7e-18 64.5 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 CDO72277.1 - 0.0039 16.6 0.0 0.033 13.5 0.0 2.1 1 1 0 1 1 1 1 Beta-galactosidase adh_short PF00106.25 CDO72279.1 - 0.0057 16.1 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_hydro_15 PF00723.21 CDO72280.1 - 2.3e-26 92.6 0.0 4.3e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 His_Phos_2 PF00328.22 CDO72281.1 - 2.7e-41 142.2 0.0 5.6e-34 118.1 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Gemini_mov PF01708.16 CDO72281.1 - 0.21 11.4 0.2 0.38 10.5 0.2 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein TF_Zn_Ribbon PF08271.12 CDO72282.1 - 0.061 12.9 1.4 0.12 12.0 1.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding EHN PF06441.12 CDO72283.1 - 2.6e-21 76.0 0.0 5e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus MFS_1 PF07690.16 CDO72284.1 - 1.8e-26 92.9 47.9 2.6e-26 92.4 47.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CDO72284.1 - 0.0029 16.2 28.4 0.0023 16.6 27.2 1.3 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 CDO72285.1 - 2e-10 40.1 37.4 5.1e-06 25.7 18.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Amnionless PF14828.6 CDO72286.1 - 0.029 13.2 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless Alpha_GJ PF03229.13 CDO72286.1 - 0.04 14.5 0.1 0.13 12.8 0.0 1.8 2 0 0 2 2 2 0 Alphavirus glycoprotein J VPDSG-CTERM PF18205.1 CDO72286.1 - 1.5 8.7 3.9 3.2 7.6 3.9 1.6 1 0 0 1 1 1 0 VPDSG-CTERM motif PTP_tm PF18861.1 CDO72287.1 - 0.0084 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J PDGLE PF13190.6 CDO72287.1 - 0.088 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 PDGLE domain SKG6 PF08693.10 CDO72287.1 - 0.44 10.0 4.1 1.1 8.7 4.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EB1 PF03271.17 CDO72288.1 - 3e-17 62.6 1.4 3e-17 62.6 1.4 1.7 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 CDO72288.1 - 1.1e-06 28.8 0.3 2e-06 27.9 0.3 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain F-box-like PF12937.7 CDO72289.1 - 4.6e-07 29.6 0.4 1.2e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 F-box-like ERbeta_N PF12497.8 CDO72290.1 - 1.5 8.7 9.7 2.3 8.0 0.0 2.3 1 1 1 2 2 2 0 Estrogen receptor beta Chitin_synth_1 PF01644.17 CDO72291.1 - 6.1e-81 270.2 0.0 9e-81 269.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CDO72291.1 - 6.3e-29 99.7 0.1 1.2e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CDO72291.1 - 6.1e-24 84.5 0.1 3.9e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CDO72291.1 - 0.017 15.1 16.6 0.36 10.7 16.6 2.6 1 1 0 1 1 1 0 Glycosyl transferase family group 2 AA_permease PF00324.21 CDO72292.1 - 4.2e-81 272.9 33.5 1.5e-76 257.9 15.3 3.0 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 CDO72292.1 - 1.2e-31 110.0 17.1 2.5e-31 109.0 17.1 1.5 1 1 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 CDO72292.1 - 0.16 11.7 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 DUF4231 PF14015.6 CDO72292.1 - 1.4 9.4 6.2 1.7 9.1 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Phage_holin_3_7 PF05449.11 CDO72293.1 - 3.1 7.9 8.1 8.2 6.5 0.6 3.2 3 0 0 3 3 3 0 Putative 3TM holin, Phage_holin_3 MFS_1 PF07690.16 CDO72294.1 - 8.9e-27 93.9 60.2 8.9e-21 74.2 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_35 PF01301.19 CDO72295.1 - 1.7e-62 211.9 1.4 2.5e-62 211.3 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 CDO72295.1 - 4.3e-50 169.0 0.1 1.6e-24 86.7 0.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 CDO72295.1 - 7.5e-34 117.1 0.1 1.3e-33 116.4 0.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 CDO72295.1 - 7.1e-20 70.4 0.1 3.1e-19 68.3 0.1 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 CDO72295.1 - 0.004 16.5 0.1 0.021 14.2 0.1 1.9 1 1 0 1 1 1 1 Beta-galactosidase adh_short PF00106.25 CDO72296.1 - 5.2e-53 179.4 0.2 6.3e-53 179.1 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO72296.1 - 3.9e-44 151.0 0.1 4.5e-44 150.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO72296.1 - 3e-15 56.6 0.5 4.4e-15 56.0 0.5 1.2 1 0 0 1 1 1 1 KR domain SASP PF00269.20 CDO72296.1 - 0.13 12.3 0.1 0.38 10.8 0.1 1.9 1 1 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type p450 PF00067.22 CDO72297.1 - 2.6e-64 217.7 0.0 5.4e-62 210.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF2499 PF10693.9 CDO72297.1 - 0.047 14.0 3.3 0.055 13.8 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) DUF4218 PF13960.6 CDO72299.1 - 0.0049 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF4407 PF14362.6 CDO72300.1 - 0.049 13.0 2.2 0.13 11.6 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLZ PF16526.5 CDO72300.1 - 0.062 13.7 0.8 0.17 12.3 0.8 1.7 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ceramidase_alk PF04734.13 CDO72300.1 - 0.13 10.9 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal Spc24 PF08286.11 CDO72300.1 - 0.45 10.8 1.9 0.49 10.7 0.4 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DSPc PF00782.20 CDO72301.1 - 7.2e-30 103.5 0.0 8.6e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CDO72301.1 - 4.6e-05 23.7 0.0 6.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 CDO72301.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDO72301.1 - 0.035 14.2 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Complex1_51K PF01512.17 CDO72302.1 - 1.9e-48 164.2 0.0 2.8e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CDO72302.1 - 8.5e-32 109.1 0.7 2.2e-31 107.8 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CDO72302.1 - 2.3e-08 33.8 0.0 5.7e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 CDO72302.1 - 0.064 13.3 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) DUF659 PF04937.15 CDO72303.1 - 3.4e-09 36.7 0.2 6.6e-09 35.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3306 PF11748.8 CDO72303.1 - 0.78 10.6 5.4 0.14 13.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Dimer_Tnp_hAT PF05699.14 CDO72304.1 - 2.4e-18 65.7 0.0 5.2e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AA_permease PF00324.21 CDO72305.1 - 3.6e-132 441.4 36.3 4.4e-132 441.1 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CDO72305.1 - 1.4e-35 123.0 39.4 1.6e-35 122.7 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease Sortilin-Vps10 PF15902.5 CDO72307.1 - 9.6e-16 57.6 8.3 0.00021 20.2 0.0 6.4 7 0 0 7 7 7 6 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 CDO72307.1 - 2.3e-13 49.9 10.4 2.3e-13 49.9 10.4 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain BNR PF02012.20 CDO72307.1 - 3.6e-10 38.3 32.4 0.35 11.0 0.0 10.2 9 0 0 9 9 9 7 BNR/Asp-box repeat BNR_6 PF15899.5 CDO72307.1 - 1.3e-08 34.1 5.0 0.035 14.1 0.0 6.4 8 0 0 8 8 8 3 BNR-Asp box repeat LRR_4 PF12799.7 CDO72308.1 - 1.8e-10 40.9 14.6 0.028 14.9 0.1 7.4 6 1 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CDO72308.1 - 0.00014 21.6 5.3 35 4.8 0.0 7.3 7 0 0 7 7 7 1 Leucine Rich repeat LRR_8 PF13855.6 CDO72308.1 - 0.00021 21.0 13.0 0.84 9.5 0.3 6.3 7 1 0 7 7 7 3 Leucine rich repeat LRR_1 PF00560.33 CDO72308.1 - 0.11 13.1 10.0 38 5.4 0.0 6.6 7 0 0 7 7 7 0 Leucine Rich Repeat DUF4224 PF13986.6 CDO72308.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) DUF846 PF05832.12 CDO72311.1 - 1e-23 83.9 23.5 4e-11 43.1 5.6 3.1 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF846) UbiA PF01040.18 CDO72311.1 - 0.0011 18.3 5.4 0.023 14.0 1.3 2.1 2 0 0 2 2 2 2 UbiA prenyltransferase family DSPc PF00782.20 CDO72312.1 - 7.8e-21 74.3 0.0 4.9e-19 68.5 0.0 2.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDO72312.1 - 0.0055 16.3 0.0 0.0083 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FAD_binding_6 PF00970.24 CDO72313.1 - 2.5e-34 117.6 0.0 4.1e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CDO72313.1 - 1.2e-32 112.8 0.0 1.7e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CDO72313.1 - 1.3e-06 28.6 0.0 0.00024 21.3 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CDO72313.1 - 0.0092 16.2 0.0 0.034 14.3 0.0 1.9 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain GST_N_3 PF13417.6 CDO72315.1 - 2.8e-08 34.1 0.0 5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO72315.1 - 0.0021 18.0 0.1 0.0047 16.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO72315.1 - 0.031 14.6 0.0 0.063 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO72315.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Jag_N PF14804.6 CDO72315.1 - 0.32 11.4 1.0 0.62 10.5 0.0 1.9 2 0 0 2 2 2 0 Jag N-terminus CAP PF00188.26 CDO72316.1 - 6.1e-23 82.0 0.4 6.1e-23 82.0 0.4 2.5 3 1 0 3 3 3 1 Cysteine-rich secretory protein family SPX PF03105.19 CDO72316.1 - 2.8 7.8 14.0 3.8 7.3 14.0 1.3 1 0 0 1 1 1 0 SPX domain DUF2012 PF09430.10 CDO72318.1 - 3.9e-11 43.1 0.0 5.9e-09 36.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2012) Fcf1 PF04900.12 CDO72319.1 - 1.9e-31 108.4 0.9 3.2e-31 107.6 0.9 1.3 1 0 0 1 1 1 1 Fcf1 WD40 PF00400.32 CDO72320.1 - 2.2e-58 192.8 14.6 1.5e-10 41.4 0.5 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO72320.1 - 6.6e-29 100.1 0.3 2e-06 28.0 0.0 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDO72320.1 - 3.8e-13 49.8 0.1 7.8e-05 22.6 0.0 4.1 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CDO72320.1 - 3.3e-10 39.2 7.1 0.0084 14.8 0.3 5.6 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CDO72320.1 - 3.8e-09 36.0 4.4 0.012 14.6 1.7 4.4 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CDO72320.1 - 1.2e-07 31.4 0.0 0.0013 18.1 0.0 3.4 2 1 1 3 3 3 2 WD40-like domain RAB3GAP2_N PF14655.6 CDO72320.1 - 0.00016 21.1 0.0 0.14 11.4 0.0 2.5 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Coatomer_WDAD PF04053.14 CDO72320.1 - 0.00093 18.3 0.0 0.027 13.5 0.0 2.6 1 1 2 3 3 3 1 Coatomer WD associated region Nbas_N PF15492.6 CDO72320.1 - 0.0045 16.4 0.3 9.7 5.4 0.0 3.4 1 1 3 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 CDO72320.1 - 0.016 14.1 0.1 0.39 9.6 0.0 2.8 1 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain IKI3 PF04762.12 CDO72320.1 - 0.039 12.0 0.0 0.3 9.0 0.1 2.2 2 1 0 2 2 2 0 IKI3 family CSN8_PSD8_EIF3K PF10075.9 CDO72321.1 - 2e-23 83.0 0.0 3.1e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Aa_trans PF01490.18 CDO72322.1 - 1.5e-56 191.9 13.0 1.9e-56 191.5 13.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CDO72322.1 - 0.0002 20.6 6.6 0.00034 19.8 6.6 1.4 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Abhydro_lipase PF04083.16 CDO72323.1 - 1e-22 79.5 0.3 1.9e-22 78.6 0.3 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CDO72323.1 - 2.3e-17 63.5 0.1 2.2e-15 57.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold WSD PF15613.6 CDO72324.1 - 7.1e-22 77.7 0.1 1.2e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WAC_Acf1_DNA_bd PF10537.9 CDO72325.1 - 2.4e-31 108.3 2.3 1.2e-25 90.0 0.6 2.9 1 1 1 2 2 2 2 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 CDO72325.1 - 1.2e-13 51.2 0.1 1.3e-12 47.9 0.0 2.5 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 CDO72325.1 - 1.3e-06 27.8 0.0 3.4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDHD PF02862.17 CDO72325.1 - 0.023 14.8 0.2 0.044 13.9 0.2 1.5 1 0 0 1 1 1 0 DDHD domain GFO_IDH_MocA PF01408.22 CDO72327.1 - 9.1e-10 39.4 0.1 1.7e-09 38.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CDO72327.1 - 0.03 14.3 0.6 0.13 12.3 0.5 2.1 1 1 1 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain Cyclin_N PF00134.23 CDO72328.1 - 2.2e-37 127.6 0.6 4.6e-37 126.6 0.6 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDO72328.1 - 1.7e-07 31.3 0.2 4.8e-07 29.9 0.2 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain Importin_rep_5 PF18816.1 CDO72329.1 - 0.1 12.9 0.2 0.21 11.9 0.2 1.4 1 0 0 1 1 1 0 Importin repeat RdRP PF05183.12 CDO72330.1 - 1.2e-179 598.8 0.0 1.6e-179 598.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase LSM PF01423.22 CDO72331.1 - 2.5e-11 43.1 0.1 3.6e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CDO72331.1 - 0.01 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Pescadillo_N PF06732.11 CDO72332.1 - 3.3e-122 407.3 0.0 3.3e-122 407.3 0.0 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 CDO72332.1 - 5e-08 33.3 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CDO72332.1 - 0.0014 19.0 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CDO72332.1 - 0.0015 18.8 0.0 0.0039 17.5 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain YL1 PF05764.13 CDO72332.1 - 0.11 12.6 26.7 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 YL1 nuclear protein Sec7 PF01369.20 CDO72333.1 - 6e-33 114.1 0.0 9.5e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 CDO72333.1 - 6.5e-13 49.1 0.0 1.2e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CDO72333.1 - 3.8e-09 37.0 0.0 8.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Con-6 PF10346.9 CDO72336.1 - 2.4e-27 94.6 9.2 1.2e-13 50.8 1.4 2.1 2 0 0 2 2 2 2 Conidiation protein 6 ATP-synt_DE PF00401.20 CDO72336.1 - 0.013 15.7 3.8 0.036 14.3 2.7 2.0 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Glyco_transf_8C PF08437.10 CDO72336.1 - 0.31 11.2 1.1 8.5 6.5 0.2 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal YhzD PF14120.6 CDO72336.1 - 0.73 10.0 3.0 5.6 7.1 0.7 2.1 2 0 0 2 2 2 0 YhzD-like protein SpoIIIAH PF12685.7 CDO72336.1 - 0.94 9.3 7.0 0.32 10.8 1.6 2.0 1 1 0 2 2 2 0 SpoIIIAH-like protein MARVEL PF01284.23 CDO72337.1 - 0.23 11.5 20.6 0.35 10.9 20.6 1.3 1 0 0 1 1 1 0 Membrane-associating domain Con-6 PF10346.9 CDO72338.1 - 5.6e-32 109.5 7.7 1.4e-15 57.0 1.6 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 CDO72338.1 - 0.0044 16.9 2.8 0.024 14.5 0.7 2.0 1 1 1 2 2 2 1 SpoIIIAH-like protein ATP-synt_DE PF00401.20 CDO72338.1 - 0.014 15.6 1.1 0.024 14.9 1.1 1.6 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain RNA_pol_Rpb8 PF03870.15 CDO72339.1 - 1e-45 155.3 0.0 1.6e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb8 TTL PF03133.15 CDO72339.1 - 6.9e-42 143.6 0.0 9.4e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family MMM1 PF10296.9 CDO72340.1 - 6.1e-22 78.1 0.0 1.1e-07 31.2 0.0 3.0 2 1 0 3 3 3 3 Maintenance of mitochondrial morphology protein 1 Nucleoporin_N PF08801.11 CDO72341.1 - 3.3e-66 223.8 0.0 5.8e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CDO72341.1 - 2.2e-33 115.9 0.0 4.9e-33 114.7 0.0 1.5 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Pkinase PF00069.25 CDO72342.1 - 5.3e-67 226.0 0.0 6.2e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO72342.1 - 6.5e-26 91.2 0.0 1.2e-25 90.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO72342.1 - 5.9e-07 29.1 0.1 7.5e-05 22.2 0.1 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 CDO72342.1 - 0.0062 16.2 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CDO72342.1 - 0.096 11.6 0.2 0.22 10.4 0.2 1.6 1 1 0 1 1 1 0 Haspin like kinase domain BRCT_2 PF16589.5 CDO72343.1 - 2.2e-11 44.0 0.0 2.5e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 CDO72343.1 - 1.8e-10 40.8 1.6 5.1e-10 39.4 1.6 1.8 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.10 CDO72343.1 - 0.28 11.8 3.5 2.3 8.8 3.5 2.4 1 1 0 1 1 1 0 Rap1, DNA-binding FAD-oxidase_C PF02913.19 CDO72344.1 - 1.7e-60 204.8 0.1 2.1e-60 204.4 0.1 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CDO72344.1 - 8.3e-34 116.3 0.4 1.7e-33 115.3 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Methyltransf_14 PF08484.11 CDO72344.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain WD40 PF00400.32 CDO72346.1 - 1.4e-07 32.1 11.7 0.14 13.1 0.2 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO72346.1 - 0.00011 22.4 0.0 0.18 12.1 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain KTSC PF13619.6 CDO72346.1 - 0.21 11.4 0.0 0.55 10.1 0.0 1.6 1 0 0 1 1 1 0 KTSC domain CSD2 PF17876.1 CDO72347.1 - 0.038 14.2 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 Cold shock domain BAF250_C PF12031.8 CDO72348.1 - 9.5e-05 21.8 0.1 0.00015 21.2 0.1 1.2 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa DUF1764 PF08576.10 CDO72349.1 - 5e-22 78.7 11.1 1.2e-20 74.2 1.3 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) Ras PF00071.22 CDO72351.1 - 2.4e-55 186.5 0.0 3e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO72351.1 - 1.2e-34 119.1 0.0 1.7e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO72351.1 - 7.8e-15 54.8 0.0 3.4e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDO72351.1 - 2e-06 27.3 0.0 2.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDO72351.1 - 3e-05 23.7 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDO72351.1 - 0.00019 21.5 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDO72351.1 - 0.00038 20.9 0.4 0.00062 20.2 0.4 1.4 1 1 0 1 1 1 1 AAA ATPase domain Usp PF00582.26 CDO72351.1 - 0.045 14.3 0.5 0.12 12.9 0.5 1.7 1 1 0 1 1 1 0 Universal stress protein family RsgA_GTPase PF03193.16 CDO72351.1 - 0.052 13.4 0.2 6.4 6.6 0.0 2.9 2 1 0 2 2 2 0 RsgA GTPase Alginate_lyase PF05426.12 CDO72352.1 - 1.2e-54 185.7 4.2 2.6e-52 178.0 2.0 2.3 2 0 0 2 2 2 2 Alginate lyase DUF5029 PF16432.5 CDO72352.1 - 0.035 13.7 0.2 0.073 12.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5029) AAA_18 PF13238.6 CDO72354.1 - 5e-32 111.2 0.0 7e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDO72354.1 - 1.8e-06 28.5 0.0 4.8e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CDO72354.1 - 1.8e-06 28.4 0.0 3.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CDO72354.1 - 6.3e-05 23.3 0.0 0.00025 21.3 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 CDO72354.1 - 6.6e-05 23.2 0.0 0.00015 22.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDO72354.1 - 0.00014 22.0 0.0 0.0018 18.4 0.0 2.1 1 1 0 2 2 2 1 AAA domain ADK PF00406.22 CDO72354.1 - 0.0003 20.9 0.0 0.006 16.7 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase dNK PF01712.19 CDO72354.1 - 0.003 17.4 0.0 0.66 9.8 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase KTI12 PF08433.10 CDO72354.1 - 0.0084 15.6 0.0 0.015 14.7 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ATPase PF06745.13 CDO72354.1 - 0.0098 15.3 0.3 0.34 10.2 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_16 PF13191.6 CDO72354.1 - 0.0099 16.3 0.1 0.015 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 CDO72354.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CDO72354.1 - 0.013 15.2 0.1 0.026 14.3 0.0 1.4 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 CDO72354.1 - 0.016 15.5 0.2 0.039 14.3 0.2 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CDO72354.1 - 0.03 14.2 0.7 0.18 11.7 0.2 2.1 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 CDO72354.1 - 0.03 14.0 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CDO72354.1 - 0.045 13.0 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 CDO72354.1 - 0.049 12.9 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CDO72354.1 - 0.062 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 CDO72354.1 - 0.076 13.1 0.1 0.35 11.0 0.1 2.0 1 1 0 1 1 1 0 Shikimate kinase T2SSE PF00437.20 CDO72354.1 - 0.098 11.7 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MeaB PF03308.16 CDO72354.1 - 0.098 11.6 0.7 0.15 11.0 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 CDO72354.1 - 0.099 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Arnt_C PF18583.1 CDO72354.1 - 0.1 12.3 0.1 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Aminoarabinose transferase C-terminal domain RNA_helicase PF00910.22 CDO72354.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RII_binding_1 PF10522.9 CDO72354.1 - 0.12 12.7 0.9 27 5.3 0.1 2.6 2 0 0 2 2 2 0 RII binding domain Viral_helicase1 PF01443.18 CDO72354.1 - 0.18 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PAPA-1 PF04795.12 CDO72357.1 - 2.7e-20 72.9 7.1 2.7e-20 72.9 7.1 2.6 3 0 0 3 3 3 1 PAPA-1-like conserved region PBP1_TM PF14812.6 CDO72357.1 - 0.038 14.4 1.2 0.038 14.4 1.2 4.7 3 2 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cyclin_C_2 PF16899.5 CDO72359.1 - 2.1e-20 73.1 0.1 2.8e-17 63.0 0.0 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 CDO72359.1 - 2.2e-09 37.1 0.4 4.8e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 CDO72359.1 - 0.0029 17.6 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Sec16_N PF12935.7 CDO72359.1 - 0.029 14.5 2.2 0.065 13.4 2.3 1.5 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 N-terminus POPLD PF08170.12 CDO72359.1 - 0.071 13.5 0.2 0.2 12.0 0.2 1.7 1 0 0 1 1 1 0 POPLD (NUC188) domain Sde2_N_Ubi PF13019.6 CDO72359.1 - 5.8 6.7 6.1 7.8 6.3 5.1 1.7 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain GYF PF02213.16 CDO72360.1 - 1.3e-15 56.7 0.0 3e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CDO72360.1 - 0.0028 17.4 0.1 0.0058 16.4 0.1 1.6 1 0 0 1 1 1 1 GYF domain 2 Amidohydro_3 PF07969.11 CDO72361.1 - 6.2e-16 58.9 0.4 2.9e-09 36.9 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 CDO72361.1 - 2.7e-14 53.2 0.0 1e-12 48.1 0.0 2.8 2 1 0 2 2 2 1 Amidohydrolase family zf-C2H2 PF00096.26 CDO72362.1 - 3.8e-14 52.2 17.4 0.0042 17.5 0.1 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO72362.1 - 7.9e-10 38.7 16.4 0.082 13.8 0.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CDO72362.1 - 0.0046 16.9 9.9 0.37 10.9 0.2 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf_ZIC PF18366.1 CDO72362.1 - 0.0062 16.6 3.9 0.68 10.1 0.0 3.7 4 0 0 4 4 4 1 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 CDO72362.1 - 0.027 14.6 5.8 0.79 9.8 0.1 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger BDHCT_assoc PF16204.5 CDO72362.1 - 0.059 13.1 1.7 0.11 12.1 0.9 1.7 1 1 0 2 2 2 0 BDHCT-box associated domain on Bloom syndrome protein zf-met PF12874.7 CDO72362.1 - 0.063 13.7 1.1 35 5.0 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 CDO72362.1 - 0.33 11.6 5.8 17 6.1 0.0 3.7 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 CDO72362.1 - 0.79 9.5 9.8 5.1 7.0 0.0 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CDO72362.1 - 3.6 8.0 7.5 22 5.5 0.8 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CDO72362.1 - 6.4 6.6 7.6 36 4.2 0.0 4.1 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Sin_N PF04801.13 CDO72363.1 - 7.2e-24 84.8 0.0 1e-23 84.3 0.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region LIM PF00412.22 CDO72364.1 - 2.4e-07 30.9 10.3 0.0042 17.3 3.0 3.8 3 1 0 3 3 3 2 LIM domain GH131_N PF18271.1 CDO72365.1 - 7.5e-59 199.5 0.0 8.5e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain DnaJ PF00226.31 CDO72368.1 - 9.9e-20 70.4 0.5 1.8e-19 69.6 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain DUF445 PF04286.12 CDO72368.1 - 0.17 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF456 PF04306.13 CDO72368.1 - 0.65 10.3 5.8 1.2 9.5 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF456) Rick_17kDa_Anti PF05433.15 CDO72368.1 - 3.6 7.5 7.2 1.9 8.4 0.1 3.0 3 0 0 3 3 3 0 Glycine zipper 2TM domain Formyl_trans_N PF00551.19 CDO72370.1 - 1.1e-38 132.8 0.0 1.8e-19 70.2 0.0 2.0 2 0 0 2 2 2 2 Formyl transferase MannoseP_isomer PF01050.18 CDO72370.1 - 0.096 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Cyt-b5 PF00173.28 CDO72371.1 - 2.1e-23 82.2 0.0 3.1e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SAP PF02037.27 CDO72372.1 - 0.024 14.4 0.2 0.063 13.0 0.2 1.7 1 0 0 1 1 1 0 SAP domain DivIC PF04977.15 CDO72372.1 - 0.11 12.3 1.2 0.23 11.3 1.2 1.5 1 0 0 1 1 1 0 Septum formation initiator Pkinase PF00069.25 CDO72373.1 - 1.6e-58 198.2 0.0 8.6e-56 189.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO72373.1 - 6.9e-26 91.1 0.0 9e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDO72373.1 - 0.0014 17.6 0.1 0.002 17.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDO72373.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDO72373.1 - 0.0032 16.8 0.1 0.0048 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO72373.1 - 0.055 13.4 0.8 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family CusF_Ec PF11604.8 CDO72374.1 - 0.045 13.7 0.0 3.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Copper binding periplasmic protein CusF Cupredoxin_1 PF13473.6 CDO72374.1 - 0.054 13.6 0.2 0.45 10.7 0.1 2.5 3 0 0 3 3 3 0 Cupredoxin-like domain NADH_dh_m_C1 PF15088.6 CDO72374.1 - 0.058 13.0 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DKCLD PF08068.12 CDO72375.1 - 3.8e-33 113.4 0.1 7e-32 109.3 0.1 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CDO72375.1 - 4.2e-24 84.5 1.0 7.5e-24 83.7 1.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 CDO72375.1 - 2e-21 75.7 1.0 3.9e-21 74.8 1.0 1.5 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 CDO72375.1 - 2.3e-21 76.7 0.2 9.5e-18 65.0 0.2 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 CDO72375.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain SOBP PF15279.6 CDO72375.1 - 4.7 7.7 7.7 7.2 7.1 7.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein APG6_N PF17675.1 CDO72375.1 - 9.5 6.8 14.9 19 5.8 14.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Ribosomal_L22e PF01776.17 CDO72376.1 - 8e-48 161.4 0.8 9.6e-48 161.1 0.8 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AdoMet_Synthase PF01941.19 CDO72376.1 - 0.014 14.2 0.1 0.015 14.1 0.1 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) HA2 PF04408.23 CDO72377.1 - 6.1e-17 61.9 0.0 1.5e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDO72377.1 - 2.8e-14 53.4 0.1 6e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDO72377.1 - 2.6e-08 34.1 0.0 6.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 CDO72377.1 - 4.7e-06 26.9 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CDO72377.1 - 0.098 13.2 0.0 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter SNF2_N PF00176.23 CDO72378.1 - 9.8e-67 225.1 1.1 1.8e-66 224.3 1.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 CDO72378.1 - 3.2e-48 163.5 17.8 3.2e-48 163.5 17.8 2.6 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 CDO72378.1 - 3.7e-16 59.4 0.0 1e-15 58.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO72378.1 - 2e-06 27.9 0.0 4.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CDO72378.1 - 3.4e-05 23.2 0.0 0.0009 18.5 0.0 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 HSA PF07529.13 CDO72378.1 - 0.31 11.4 13.3 2.4 8.6 13.3 2.7 1 1 0 1 1 1 0 HSA DNA_pol_B_thumb PF14791.6 CDO72378.1 - 0.37 11.0 1.5 0.71 10.1 0.2 2.2 2 0 0 2 2 2 0 DNA polymerase beta thumb Lyase_1 PF00206.20 CDO72379.1 - 5.5e-119 397.2 0.0 7.2e-119 396.8 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CDO72379.1 - 7.8e-20 71.0 0.1 1.8e-19 69.9 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.12 CDO72379.1 - 0.052 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain P22_Cro PF14549.6 CDO72379.1 - 0.082 12.8 0.2 8.1 6.4 0.0 2.5 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro G-alpha PF00503.20 CDO72379.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PEX11 PF05648.14 CDO72380.1 - 1.5e-50 171.7 1.4 1.7e-50 171.5 1.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4190 PF13828.6 CDO72380.1 - 0.03 14.1 0.1 5.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) LIAS_N PF16881.5 CDO72381.1 - 4.3e-26 91.5 0.0 1.2e-25 90.0 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CDO72381.1 - 3.4e-08 34.1 0.1 6.9e-08 33.0 0.1 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Glyco_transf_8 PF01501.20 CDO72382.1 - 5.4e-08 32.7 0.0 7.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Peptidase_M22 PF00814.25 CDO72383.1 - 9.6e-83 278.0 0.0 1.1e-82 277.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family HTH_13 PF11972.8 CDO72383.1 - 0.066 13.3 0.3 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain Carbam_trans_N PF02543.15 CDO72383.1 - 0.076 12.7 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus AlaDh_PNT_N PF05222.15 CDO72384.1 - 1.7e-11 44.6 0.0 2.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 CDO72384.1 - 0.00088 18.6 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Acyltransferase PF01553.21 CDO72387.1 - 1.6e-21 76.3 0.0 2.6e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CDO72387.1 - 3.7e-08 33.3 0.0 6.4e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase C-terminus Aa_trans PF01490.18 CDO72388.1 - 3.2e-32 111.7 37.7 4.1e-32 111.4 37.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Enoyl_reductase PF12241.8 CDO72388.1 - 0.071 12.5 1.3 0.089 12.1 0.1 1.7 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region GTA_holin_3TM PF11351.8 CDO72388.1 - 5 7.7 7.8 17 5.9 1.5 3.2 2 1 1 3 3 3 0 Holin of 3TMs, for gene-transfer release CoxIIa PF08113.11 CDO72388.1 - 5.3 6.9 8.2 0.21 11.4 0.6 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family LRR_4 PF12799.7 CDO72389.1 - 7e-05 23.1 3.8 2.4 8.7 0.5 4.9 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDO72389.1 - 0.0048 16.6 2.5 0.072 12.9 0.0 3.4 4 0 0 4 4 4 1 Leucine rich repeat Hydrolase_4 PF12146.8 CDO72390.1 - 8.8e-09 35.0 0.2 1.1e-05 24.8 0.0 2.7 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDO72390.1 - 1.6e-06 27.9 0.0 4.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 CDO72390.1 - 0.032 12.9 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family Erythro_esteras PF05139.14 CDO72391.1 - 3.8e-103 345.9 1.1 4.9e-103 345.5 1.1 1.2 1 0 0 1 1 1 1 Erythromycin esterase TMEM154 PF15102.6 CDO72391.1 - 0.0038 17.1 0.4 0.0038 17.1 0.4 3.0 1 1 1 2 2 2 1 TMEM154 protein family PRIMA1 PF16101.5 CDO72391.1 - 0.039 14.0 0.4 0.039 14.0 0.4 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF3377 PF11857.8 CDO72391.1 - 0.97 9.4 2.6 2 8.4 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Cas_Csd1 PF09709.10 CDO72392.1 - 0.047 12.4 0.0 0.053 12.2 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) MIT PF04212.18 CDO72393.1 - 0.0018 18.3 0.1 0.0055 16.7 0.1 1.9 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF3543 PF12063.8 CDO72393.1 - 0.0039 16.6 1.3 0.0068 15.8 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Septin PF00735.18 CDO72394.1 - 7.2e-110 366.7 0.0 1.2e-109 365.9 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CDO72394.1 - 1.8e-06 28.0 0.0 4.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDO72394.1 - 0.00063 19.8 3.5 0.077 13.0 0.0 3.0 2 1 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 CDO72394.1 - 0.0069 15.9 0.1 0.3 10.6 0.0 2.7 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CDO72394.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family FtsK_SpoIIIE PF01580.18 CDO72394.1 - 0.032 13.6 0.1 0.097 12.0 0.1 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 CDO72394.1 - 0.054 13.4 3.8 0.13 12.1 0.5 2.9 3 1 0 3 3 3 0 RsgA GTPase IIGP PF05049.13 CDO72394.1 - 0.11 11.6 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MutS_V PF00488.21 CDO72395.1 - 1.6e-68 230.4 0.0 3e-68 229.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CDO72395.1 - 3.1e-38 131.9 4.8 6e-38 131.0 4.8 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CDO72395.1 - 1.1e-23 83.6 0.0 4.3e-23 81.7 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 CDO72395.1 - 5.9e-10 39.6 0.4 1.3e-09 38.5 0.0 1.8 2 0 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 CDO72395.1 - 3.8e-05 23.4 0.0 0.00012 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CDO72395.1 - 0.00063 20.3 0.1 0.0082 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDO72395.1 - 0.0075 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 CDO72395.1 - 0.058 13.4 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain SASRP1 PF15160.6 CDO72395.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 DUF3126 PF11324.8 CDO72395.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) Aconitase PF00330.20 CDO72396.1 - 2.7e-139 465.2 0.1 1.8e-138 462.4 0.1 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDO72396.1 - 7.5e-35 120.1 0.0 1.5e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 CDO72396.1 - 0.00017 20.4 0.0 0.0011 17.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF521) ATG16 PF08614.11 CDO72398.1 - 7e-52 176.6 13.3 7e-52 176.6 13.3 1.4 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Flagellar_rod PF05149.12 CDO72398.1 - 0.0023 17.5 0.8 0.0023 17.5 0.8 2.3 2 1 0 2 2 2 1 Paraflagellar rod protein TMF_TATA_bd PF12325.8 CDO72398.1 - 0.0056 16.9 24.9 0.077 13.2 4.8 3.0 3 0 0 3 3 3 2 TATA element modulatory factor 1 TATA binding YabA PF06156.13 CDO72398.1 - 0.053 14.2 3.1 0.053 14.2 3.1 3.1 3 1 0 3 3 3 0 Initiation control protein YabA FlaC_arch PF05377.11 CDO72398.1 - 0.15 12.5 6.5 16 6.0 0.1 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 CDO72398.1 - 0.48 9.2 20.5 0.033 13.1 6.8 2.4 3 0 0 3 3 3 0 Spc7 kinetochore protein SOGA PF11365.8 CDO72398.1 - 0.71 11.0 14.8 0.33 12.1 3.6 2.8 2 1 0 2 2 2 0 Protein SOGA DASH_Dam1 PF08653.10 CDO72398.1 - 1.1 9.1 5.0 2.9 7.8 0.2 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 Cep57_MT_bd PF06657.13 CDO72398.1 - 1.4 9.5 10.2 0.27 11.7 0.5 3.2 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Atg14 PF10186.9 CDO72398.1 - 2.1 7.4 14.8 1.7 7.7 1.4 2.4 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 CDO72398.1 - 2.3 8.7 29.0 0.96 9.9 10.1 4.5 3 2 0 3 3 2 0 Cell division protein ZapB DUF1664 PF07889.12 CDO72398.1 - 3.1 7.9 6.3 1.9 8.5 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 CDO72398.1 - 4.2 7.8 20.6 0.56 10.6 4.7 3.0 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 CDO72398.1 - 8.3 6.6 12.2 9.7 6.4 2.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 CDO72398.1 - 9.2 6.8 9.6 4.3 7.9 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Ras PF00071.22 CDO72399.1 - 1.3e-57 194.0 0.2 1.5e-57 193.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO72399.1 - 2.7e-32 111.5 0.0 4.4e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO72399.1 - 3.8e-14 52.5 0.0 4.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CDO72399.1 - 2.1e-07 31.0 0.0 3.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDO72399.1 - 1.4e-06 27.8 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CDO72399.1 - 2.9e-06 27.0 0.0 6.3e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDO72399.1 - 9.4e-05 22.4 0.2 0.0056 16.6 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 CDO72399.1 - 0.00078 19.3 0.5 0.025 14.3 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CDO72399.1 - 0.00098 18.9 0.1 0.21 11.3 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CDO72399.1 - 0.0027 17.3 0.0 0.0083 15.7 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 CDO72399.1 - 0.0047 16.2 0.2 0.067 12.5 0.0 2.2 2 1 0 2 2 2 1 Septin SRPRB PF09439.10 CDO72399.1 - 0.0081 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CDO72399.1 - 0.0088 16.4 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDO72399.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CDO72399.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CDO72399.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CDO72399.1 - 0.038 14.0 0.0 0.066 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 CDO72399.1 - 0.058 13.3 0.5 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ribonuc_red_2_N PF08471.10 CDO72399.1 - 0.069 13.3 0.1 0.16 12.2 0.1 1.7 1 1 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase NTPase_1 PF03266.15 CDO72399.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 CDO72399.1 - 0.099 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Glyco_hydro_75 PF07335.11 CDO72399.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 AAA_18 PF13238.6 CDO72399.1 - 0.19 12.3 0.0 1.3 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Oxysterol_BP PF01237.18 CDO72400.1 - 2.8e-117 391.7 0.2 1e-116 389.8 0.2 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 CDO72400.1 - 5e-16 58.8 0.2 1.8e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CDO72400.1 - 1e-07 32.4 0.0 2.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Glyco_hydro_3_C PF01915.22 CDO72401.1 - 1.3e-49 168.9 0.2 3.4e-49 167.6 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CDO72401.1 - 3.1e-22 79.4 0.1 1.9e-15 57.1 0.1 3.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CDO72401.1 - 3.3e-18 65.6 0.0 8.3e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DARPP-32 PF05395.12 CDO72401.1 - 0.23 11.6 0.1 0.38 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF11 PF01345.18 CDO72401.1 - 2.6 8.4 6.6 1.2 9.5 2.7 2.6 2 1 0 2 2 2 0 Domain of unknown function DUF11 RRM_1 PF00076.22 CDO72404.1 - 1e-40 137.4 0.0 1.9e-13 50.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDO72404.1 - 2.6e-06 27.0 0.0 0.0018 17.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDO72404.1 - 6.9e-05 22.6 0.0 0.00069 19.4 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CDO72404.1 - 0.058 13.5 0.0 0.23 11.6 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CDO72404.1 - 0.087 12.8 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Band_7 PF01145.25 CDO72405.1 - 4.7e-24 85.4 3.3 1.2e-23 84.1 3.3 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CDO72405.1 - 6.5e-06 25.4 2.7 9.2e-06 24.9 2.7 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF4587 PF15248.6 CDO72405.1 - 0.17 12.7 0.1 0.3 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) PRODH PF18327.1 CDO72406.1 - 5.2 7.4 8.1 12 6.2 0.1 3.3 3 0 0 3 3 3 0 Proline utilization A proline dehydrogenase N-terminal domain Plavaka PF18759.1 CDO72407.1 - 8e-52 176.5 7.3 7.6e-26 91.1 4.9 3.3 1 1 1 2 2 2 2 Plavaka transposase Asn_synthase PF00733.21 CDO72408.1 - 2.8e-18 66.7 0.1 3.6e-09 36.7 0.0 2.8 1 1 1 2 2 2 2 Asparagine synthase QueC PF06508.13 CDO72408.1 - 0.085 12.3 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC HA2 PF04408.23 CDO72409.1 - 3.9e-25 88.2 0.0 3.9e-25 88.2 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDO72409.1 - 1.3e-20 73.5 0.0 3.2e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDO72409.1 - 7.4e-10 39.1 0.4 1.2e-08 35.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDO72409.1 - 8.7e-08 32.1 0.0 1.9e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDO72409.1 - 1.7e-06 28.4 0.8 5.3e-05 23.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 CDO72409.1 - 0.0041 17.1 0.0 0.057 13.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CDO72409.1 - 0.0074 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CDO72409.1 - 0.0078 16.6 0.0 0.028 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDO72409.1 - 0.0085 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CDO72409.1 - 0.013 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 CDO72409.1 - 0.27 11.7 14.1 0.73 10.3 1.2 2.8 2 1 0 2 2 2 0 AAA domain ORC_WH_C PF18137.1 CDO72410.1 - 3e-43 147.3 1.5 3.1e-43 147.2 0.1 1.7 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal 6PGD PF00393.19 CDO72411.1 - 1e-124 415.7 0.0 1.2e-124 415.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CDO72411.1 - 7.2e-48 162.7 0.0 1.1e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CoatB PF10389.9 CDO72411.1 - 1.6 8.6 5.7 2.9 7.8 0.3 2.4 2 0 0 2 2 2 0 Bacteriophage coat protein B Aminotran_4 PF01063.19 CDO72412.1 - 1.5e-26 93.6 0.0 2.8e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Amino-transferase class IV IBR PF01485.21 CDO72415.1 - 4.8e-10 39.5 26.8 8.7e-06 25.9 11.3 2.8 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain HIT PF01230.23 CDO72416.1 - 5.9e-18 65.4 0.8 4.6e-16 59.3 0.1 2.4 1 1 1 2 2 2 2 HIT domain DcpS_C PF11969.8 CDO72416.1 - 0.0011 19.5 0.3 0.003 18.0 0.3 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Glucosamine_iso PF01182.20 CDO72417.1 - 1.3e-74 250.8 0.0 1.5e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Lac_bphage_repr PF06543.12 CDO72417.1 - 0.031 14.3 0.1 0.073 13.1 0.1 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Evf PF18270.1 CDO72417.1 - 0.22 10.9 0.0 0.33 10.3 0.0 1.1 1 0 0 1 1 1 0 Virulence factor Evf PXA PF02194.15 CDO72418.1 - 1.7e-14 54.2 0.1 2.2e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 PXA domain TMEM132D_N PF15705.5 CDO72418.1 - 0.051 13.4 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term PWI PF01480.17 CDO72420.1 - 6.1e-11 42.5 0.0 1.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 CDO72420.1 - 0.0042 16.9 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDO72420.1 - 0.015 15.3 0.1 0.038 14.1 0.1 1.6 1 0 0 1 1 1 0 RNA binding motif TFIIA PF03153.13 CDO72420.1 - 0.22 11.5 6.2 0.36 10.8 6.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 CDO72420.1 - 1.3 8.7 10.1 2.9 7.6 10.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein IBR PF01485.21 CDO72421.1 - 3.4e-13 49.6 24.3 2.1e-07 31.1 3.4 2.7 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CDO72421.1 - 0.0013 19.0 3.0 0.0013 19.0 3.0 3.8 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 CDO72421.1 - 0.0027 17.5 0.7 0.0027 17.5 0.7 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO72421.1 - 0.0059 16.5 0.6 0.0059 16.5 0.6 3.9 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sld5 PF05916.11 CDO72423.1 - 0.0031 18.0 0.0 0.0042 17.5 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 CDO72423.1 - 0.14 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus LysM PF01476.20 CDO72424.1 - 1.7e-14 53.6 0.8 1.7e-07 31.2 0.2 2.2 2 0 0 2 2 2 2 LysM domain fn2 PF00040.19 CDO72424.1 - 0.43 10.9 0.0 0.43 10.9 0.0 2.6 3 0 0 3 3 3 0 Fibronectin type II domain Agro_virD5 PF04730.12 CDO72424.1 - 0.64 8.5 4.8 0.33 9.4 0.1 2.0 2 0 0 2 2 2 0 Agrobacterium VirD5 protein ParA PF10609.9 CDO72425.1 - 2e-79 266.5 0.0 2.5e-79 266.2 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CDO72425.1 - 6.8e-11 42.3 0.0 2.2e-10 40.7 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CDO72425.1 - 2.1e-09 37.5 0.1 2e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 CDO72425.1 - 0.00053 19.4 0.0 0.0012 18.2 0.0 1.6 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 CDO72425.1 - 0.0012 18.5 0.2 0.0022 17.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 CDO72425.1 - 0.0045 16.2 3.6 0.0052 16.0 0.6 2.2 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 CDO72425.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ResIII PF04851.15 CDO72426.1 - 3.1e-22 79.4 0.0 7.3e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDO72426.1 - 3.1e-20 72.6 0.0 1.2e-19 70.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDO72426.1 - 4.1e-17 62.5 0.0 1.2e-16 60.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CDO72426.1 - 0.003 17.3 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 CDO72426.1 - 0.019 15.3 0.0 0.15 12.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain PGA2 PF07543.12 CDO72426.1 - 0.19 11.7 1.7 0.46 10.5 1.7 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 G-patch PF01585.23 CDO72428.1 - 1.1e-11 44.4 0.1 2.6e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 CDO72428.1 - 3.5e-06 27.1 5.3 5.3e-06 26.6 5.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDO72428.1 - 4e-05 23.9 1.6 6.2e-05 23.2 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.7 CDO72428.1 - 0.00036 20.6 0.0 0.00036 20.6 0.0 2.5 3 0 0 3 3 3 1 G-patch domain zf-DBF PF07535.12 CDO72428.1 - 0.005 16.9 3.4 0.0082 16.2 3.4 1.3 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_2 PF12756.7 CDO72428.1 - 0.0059 16.9 0.6 0.0097 16.2 0.6 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 CDO72428.1 - 0.078 13.1 0.4 0.13 12.4 0.4 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger DUF393 PF04134.12 CDO72428.1 - 0.96 10.8 2.7 0.48 11.8 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF393 DUF4820 PF16091.5 CDO72428.1 - 4 6.7 11.1 5.6 6.3 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Bromodomain PF00439.25 CDO72429.1 - 2.3e-41 139.7 0.1 1.9e-22 79.1 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 CDO72429.1 - 6e-20 71.2 0.7 1.4e-19 70.0 0.7 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation SPT6_acidic PF14632.6 CDO72429.1 - 0.046 14.3 8.7 0.17 12.5 8.7 2.1 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF1664 PF07889.12 CDO72429.1 - 0.31 11.1 0.5 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3381 PF11861.8 CDO72429.1 - 0.67 9.7 8.8 2.5 7.9 8.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FlxA PF14282.6 CDO72429.1 - 3.4 7.7 5.8 1.1 9.3 1.8 2.3 2 0 0 2 2 2 0 FlxA-like protein WD40 PF00400.32 CDO72430.1 - 2.6e-19 69.2 10.3 0.00053 20.7 0.2 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO72430.1 - 1.4e-05 25.2 0.1 0.58 10.5 0.0 5.1 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDO72430.1 - 1.5e-05 24.9 0.1 0.28 11.0 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDO72430.1 - 8.7e-05 21.6 0.2 0.00029 19.9 0.0 1.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein LRV PF01816.17 CDO72430.1 - 0.3 11.6 1.6 0.57 10.7 0.1 2.3 2 0 0 2 2 2 0 Leucine rich repeat variant SRF-TF PF00319.18 CDO72431.1 - 0.0039 16.6 0.0 0.0081 15.6 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MAM33 PF02330.16 CDO72431.1 - 0.025 14.5 0.8 0.044 13.7 0.8 1.5 1 1 0 1 1 1 0 Mitochondrial glycoprotein LpxD PF04613.14 CDO72431.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Rhodanese PF00581.20 CDO72433.1 - 5e-16 59.2 0.0 8.4e-16 58.4 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Multi_ubiq PF14452.6 CDO72433.1 - 0.085 13.1 0.0 0.34 11.2 0.1 1.9 2 0 0 2 2 2 0 Multiubiquitin Ctr PF04145.15 CDO72434.1 - 2.3e-29 103.0 0.0 2.7e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family MGC-24 PF05283.11 CDO72435.1 - 0.14 12.6 5.6 0.24 11.8 5.6 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF515 PF04415.12 CDO72435.1 - 0.8 8.0 6.1 0.95 7.8 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Alpha-amylase_N PF02903.14 CDO72436.1 - 0.018 15.2 0.2 0.019 15.1 0.2 1.0 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain XRCC4 PF06632.12 CDO72436.1 - 0.032 13.1 0.3 0.037 12.9 0.3 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SSFA2_C PF14723.6 CDO72436.1 - 0.045 13.6 0.0 0.046 13.6 0.0 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus V-ATPase_C PF03223.15 CDO72437.1 - 1.5e-108 363.5 2.9 1.7e-60 205.4 0.2 2.0 1 1 1 2 2 2 2 V-ATPase subunit C Urb2 PF10441.9 CDO72438.1 - 3.9e-45 154.3 0.0 1.2e-44 152.7 0.0 1.9 1 0 0 1 1 1 1 Urb2/Npa2 family Beta_elim_lyase PF01212.21 CDO72439.1 - 3.5e-60 203.8 0.0 6.6e-38 130.7 0.0 2.2 1 1 1 2 2 2 2 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CDO72439.1 - 0.076 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-met2 PF12907.7 CDO72440.1 - 1e-16 60.8 1.7 1.4e-16 60.3 1.7 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 CDO72440.1 - 7.1e-09 36.4 10.0 7.1e-09 36.4 10.0 1.8 2 0 0 2 2 2 1 4F5 protein family zf-Tim10_DDP PF02953.15 CDO72441.1 - 3.5e-21 74.6 0.5 4e-21 74.4 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger WD40 PF00400.32 CDO72442.1 - 4.4e-06 27.3 15.6 0.01 16.7 0.1 7.0 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO72442.1 - 0.00015 22.0 0.1 0.12 12.7 0.0 4.5 5 2 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BAT PF15915.5 CDO72442.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 GAF and HTH_10 associated domain Mpv17_PMP22 PF04117.12 CDO72443.1 - 1.2e-24 86.3 0.3 2.4e-24 85.3 0.3 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family PTH2 PF01981.16 CDO72444.1 - 7.6e-07 29.4 0.2 4.3e-06 27.0 0.2 1.9 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 DEAD PF00270.29 CDO72445.1 - 2.5e-45 154.4 0.0 4.4e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO72445.1 - 2.9e-25 88.7 0.0 1.8e-24 86.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CDO72445.1 - 5.5e-17 61.7 0.4 1.1e-16 60.8 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CDO72445.1 - 0.00036 20.6 0.0 0.00077 19.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PBP1_TM PF14812.6 CDO72445.1 - 1.9 8.9 9.4 4.9 7.6 9.4 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0121 PF03661.13 CDO72446.1 - 8e-38 130.2 0.3 1e-37 129.8 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) NdhL PF10716.9 CDO72446.1 - 0.083 12.9 5.9 0.09 12.8 0.2 2.4 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit Oxidored_q4 PF00507.19 CDO72447.1 - 0.12 12.5 3.8 0.16 12.1 3.8 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF1700 PF08006.11 CDO72447.1 - 2.1 7.9 8.1 2.5 7.6 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) CBS PF00571.28 CDO72448.1 - 8.7e-34 115.8 3.8 1e-09 38.7 0.0 4.6 4 0 0 4 4 4 4 CBS domain Sgf11 PF08209.11 CDO72448.1 - 3e-14 52.3 0.7 6.6e-14 51.2 0.7 1.6 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) MFS_1 PF07690.16 CDO72449.1 - 6.8e-07 28.5 21.4 1.3e-05 24.3 21.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0242 PF06785.11 CDO72450.1 - 0.005 17.0 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Spo7 PF03907.13 CDO72450.1 - 5.9 6.3 6.1 1 8.8 1.9 1.8 2 0 0 2 2 2 0 Spo7-like protein Bac_rhamnosid6H PF17389.2 CDO72451.1 - 3e-13 49.7 0.3 1.5e-12 47.4 0.1 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 CDO72451.1 - 1.3e-09 37.7 0.3 1.6e-08 34.3 0.0 2.7 3 0 0 3 3 3 1 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 CDO72451.1 - 0.011 14.6 0.1 0.042 12.8 0.1 1.7 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.11 CDO72451.1 - 0.023 14.7 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain CarboxypepD_reg PF13620.6 CDO72451.1 - 0.038 14.2 0.3 3 8.2 0.0 2.8 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Use1 PF09753.9 CDO72452.1 - 0.04 13.6 0.1 0.053 13.2 0.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Synaptobrevin PF00957.21 CDO72452.1 - 0.15 11.9 1.0 0.3 10.9 1.0 1.4 1 0 0 1 1 1 0 Synaptobrevin Peptidase_C48 PF02902.19 CDO72453.1 - 6.8e-38 130.7 0.1 6.8e-38 130.7 0.1 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF3347 PF11827.8 CDO72453.1 - 0.68 10.1 7.1 1.5 9.0 7.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) HTH_32 PF13565.6 CDO72453.1 - 2.9 8.6 6.8 0.86 10.3 0.9 3.0 2 1 0 2 2 2 0 Homeodomain-like domain Neur_chan_memb PF02932.16 CDO72453.1 - 5.3 7.0 5.3 14 5.7 5.3 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.25 CDO72454.1 - 1.4e-47 162.3 0.0 1.9e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO72454.1 - 2.3e-26 92.6 0.0 3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO72454.1 - 0.0013 18.7 0.0 0.0045 17.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDO72454.1 - 0.0027 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDO72454.1 - 0.063 12.0 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Yippee-Mis18 PF03226.14 CDO72455.1 - 7.3e-11 42.2 0.0 7.5e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.9 CDO72455.1 - 0.042 14.2 0.1 0.049 14.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.8 CDO72455.1 - 0.048 13.9 0.0 0.06 13.6 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of RIG-I DUF1729 PF08354.10 CDO72456.1 - 1e-104 350.3 0.0 1.4e-104 349.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) TubC_N PF18563.1 CDO72456.1 - 0.18 11.8 1.2 0.38 10.8 0.3 2.1 2 1 0 2 2 2 0 TubC N-terminal docking domain Cornichon PF03311.14 CDO72459.1 - 4.3e-54 182.0 7.9 4.9e-54 181.8 7.9 1.0 1 0 0 1 1 1 1 Cornichon protein Coilin_N PF15862.5 CDO72460.1 - 0.34 10.7 6.1 0.49 10.2 6.1 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF4398 PF14346.6 CDO72460.1 - 0.42 11.3 21.5 0.59 10.8 21.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DBINO PF13892.6 CDO72460.1 - 0.85 10.0 15.2 1.4 9.3 15.2 1.4 1 0 0 1 1 1 0 DNA-binding domain Cerato-platanin PF07249.12 CDO72461.1 - 1.5e-38 131.6 4.6 2.7e-38 130.7 4.6 1.4 1 0 0 1 1 1 1 Cerato-platanin PRMT5_C PF17286.2 CDO72463.1 - 5.2e-60 202.3 0.0 7.4e-60 201.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 CDO72463.1 - 1.1e-58 198.4 0.1 1.3e-56 191.6 0.1 2.3 1 1 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 CDO72463.1 - 1.7e-56 190.8 0.0 4.3e-56 189.5 0.0 1.6 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Ank_5 PF13857.6 CDO72463.1 - 1.8e-12 47.2 0.2 7.6e-11 42.0 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDO72463.1 - 2.7e-12 46.9 0.0 6e-06 26.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDO72463.1 - 2e-09 37.9 0.0 5.2e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDO72463.1 - 5e-08 33.0 0.2 0.00069 20.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CDO72463.1 - 1.5e-06 28.1 0.0 0.00023 21.3 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Methyltransf_25 PF13649.6 CDO72463.1 - 8.8e-05 23.1 0.0 0.0002 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CDO72463.1 - 0.0066 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 CDO72463.1 - 0.017 15.8 0.0 0.036 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GATA PF00320.27 CDO72464.1 - 6e-14 51.4 2.8 1.3e-13 50.2 2.8 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 CDO72464.1 - 0.0021 18.3 0.1 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 CDO72464.1 - 0.0098 16.2 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 PAS fold DUF2318 PF10080.9 CDO72464.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) LRR_4 PF12799.7 CDO72465.1 - 9.6e-27 92.6 19.7 1.5e-09 38.0 1.4 4.4 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDO72465.1 - 3e-24 84.5 19.6 3e-10 39.7 2.4 4.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CDO72465.1 - 1.4e-15 57.3 6.3 1.1e-09 38.0 0.3 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 CDO72465.1 - 7.2e-05 22.8 21.4 2.6 8.9 0.2 7.0 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 CDO72465.1 - 8.3e-05 22.3 16.6 0.93 9.7 0.8 6.0 7 0 0 7 7 7 3 Leucine Rich repeat LRR_5 PF13306.6 CDO72465.1 - 0.049 13.6 0.2 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) DUF4078 PF13300.6 CDO72466.1 - 4e-16 59.1 28.3 9.3e-15 54.7 21.6 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4078) Acyl-thio_N PF12590.8 CDO72466.1 - 0.26 11.9 1.3 0.42 11.2 0.3 1.9 2 0 0 2 2 2 0 Acyl-ATP thioesterase Lactamase_B PF00753.27 CDO72467.1 - 2.1e-11 44.2 2.1 3.6e-10 40.2 2.1 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDO72467.1 - 0.0015 18.1 0.6 0.0031 17.1 0.6 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ThiS PF02597.20 CDO72468.1 - 8.4e-07 29.6 0.0 7.6e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 ThiS family TPK_catalytic PF04263.16 CDO72469.1 - 3.7e-26 91.5 0.0 6e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CDO72469.1 - 2.3e-22 78.5 0.2 3.5e-22 77.9 0.2 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CS PF04969.16 CDO72470.1 - 1e-07 32.9 0.0 3.2e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 CS domain Erg28 PF03694.13 CDO72472.1 - 1.4e-36 125.2 2.5 1.9e-36 124.8 2.5 1.2 1 0 0 1 1 1 1 Erg28 like protein LRR_6 PF13516.6 CDO72473.1 - 2.8e-06 26.9 0.3 0.0011 18.9 0.0 4.2 5 0 0 5 5 5 1 Leucine Rich repeat F-box-like PF12937.7 CDO72473.1 - 2e-05 24.4 0.1 7.5e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CDO72473.1 - 0.0047 17.3 0.2 0.44 11.0 0.1 3.7 3 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDO72473.1 - 0.18 11.6 0.1 17 5.3 0.1 3.0 2 1 0 2 2 2 0 Leucine rich repeat Na_Ca_ex PF01699.24 CDO72474.1 - 2.9e-32 111.7 33.0 5.4e-19 68.6 14.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein adh_short PF00106.25 CDO72475.1 - 1.2e-88 295.6 17.7 2.3e-44 151.2 5.7 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO72475.1 - 1.4e-69 234.2 16.8 1.5e-35 122.8 4.0 3.2 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO72475.1 - 1.6e-23 83.6 11.1 6.9e-15 55.4 2.9 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 CDO72475.1 - 9.1e-18 64.0 0.0 2.4e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CDO72475.1 - 2.1e-06 27.9 0.0 8.6e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.18 CDO72475.1 - 3.8e-05 23.6 10.0 0.0049 16.8 1.8 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CDO72475.1 - 0.00051 19.5 4.6 0.22 10.9 0.1 3.5 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CDO72475.1 - 0.081 12.2 8.8 0.15 11.4 0.8 2.9 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CoA_binding PF02629.19 CDO72475.1 - 0.13 12.9 1.9 0.53 11.0 0.1 2.9 2 0 0 2 2 2 0 CoA binding domain DUF543 PF04418.12 CDO72475.1 - 0.21 11.6 4.5 6.6 6.8 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Shikimate_DH PF01488.20 CDO72475.1 - 2.9 8.0 5.7 4.2 7.4 0.4 2.9 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase CoA_transf_3 PF02515.17 CDO72476.1 - 2.3e-40 138.8 0.0 1.2e-28 100.4 0.0 2.1 1 1 1 2 2 2 2 CoA-transferase family III Drf_GBD PF06371.13 CDO72477.1 - 5.3e-13 49.0 0.0 3.5e-12 46.3 0.0 2.1 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain CRAL_TRIO PF00650.20 CDO72479.1 - 1.7e-31 109.1 0.0 2.3e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDO72479.1 - 8.4e-14 51.5 1.8 1.2e-13 51.0 0.0 2.2 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CDO72479.1 - 0.0033 17.6 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Complex1_LYR PF05347.15 CDO72480.1 - 2.4e-12 46.7 0.2 5.1e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CDO72480.1 - 0.00049 20.8 1.5 0.0006 20.5 1.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Glyco_hydro_17 PF00332.18 CDO72482.1 - 3.9e-07 30.0 6.6 1.1e-05 25.2 6.6 2.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 RhoGAP PF00620.27 CDO72483.1 - 1.6e-38 132.0 0.0 2.8e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Spt20 PF12090.8 CDO72483.1 - 0.0093 15.6 0.6 12 5.4 0.0 2.3 1 1 1 2 2 2 1 Spt20 family DUF1899 PF08953.11 CDO72483.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) DUF1708 PF08101.11 CDO72483.1 - 0.1 11.7 0.0 0.1 11.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1708) Dor1 PF04124.12 CDO72485.1 - 0.15 10.7 6.9 0.45 9.1 0.0 2.1 2 0 0 2 2 2 0 Dor1-like family DUF4407 PF14362.6 CDO72485.1 - 0.26 10.6 5.1 0.47 9.8 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Spc19 PF08287.11 CDO72485.1 - 0.7 9.8 16.2 0.18 11.7 12.4 1.8 2 0 0 2 2 2 0 Spc19 Med9 PF07544.13 CDO72485.1 - 1.2 9.3 11.2 0.78 9.9 7.5 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Phlebovirus_NSM PF07246.11 CDO72485.1 - 1.5 8.1 8.2 3 7.1 8.2 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Cnn_1N PF07989.11 CDO72485.1 - 1.8 8.8 19.9 0.079 13.1 9.5 3.1 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF1764 PF08576.10 CDO72485.1 - 3 8.8 7.1 5.7 7.9 7.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF724 PF05266.14 CDO72485.1 - 4.5 7.1 12.7 0.85 9.4 8.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) COX16 PF14138.6 CDO72485.1 - 4.8 7.8 7.4 12 6.5 7.4 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 LCD1 PF09798.9 CDO72485.1 - 6 5.3 14.1 0.79 8.2 9.9 1.5 2 0 0 2 2 2 0 DNA damage checkpoint protein CSN7a_helixI PF18392.1 CDO72485.1 - 7.2 6.6 6.8 1.3 9.0 0.2 2.6 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Ferritin_2 PF13668.6 CDO72486.1 - 1.4e-10 41.5 0.1 2.1e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF5039 PF16442.5 CDO72486.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) Oxidored_FMN PF00724.20 CDO72487.1 - 1.5e-103 346.7 0.0 1.7e-103 346.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pectate_lyase_3 PF12708.7 CDO72488.1 - 5.1e-85 284.7 24.7 1.4e-73 247.3 11.8 3.0 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 CDO72488.1 - 1.3e-05 24.8 4.2 0.0038 16.9 0.6 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Ribosomal_L5_C PF00673.21 CDO72489.1 - 3.8e-19 68.7 0.0 6.9e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CDO72489.1 - 1.2e-11 44.8 0.0 3.2e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L5 Josephin PF02099.17 CDO72490.1 - 7.7e-09 35.9 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Josephin UIM PF02809.20 CDO72490.1 - 0.04 13.8 3.0 0.04 13.8 3.0 4.9 5 0 0 5 5 5 0 Ubiquitin interaction motif FUSC PF04632.12 CDO72490.1 - 1.8 7.0 12.2 2.9 6.3 12.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG27 PF09451.10 CDO72491.1 - 1.2e-65 222.0 0.0 1.5e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 CDO72491.1 - 0.00085 18.5 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor AIM24 PF01987.17 CDO72493.1 - 5.7e-50 169.9 0.1 6.7e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 stn_TNFRSF12A PF12191.8 CDO72494.1 - 0.067 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Phage_holin_2_4 PF16082.5 CDO72494.1 - 0.13 12.0 0.7 0.19 11.5 0.7 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like ILVD_EDD PF00920.21 CDO72495.1 - 2.9e-203 676.2 0.0 3.6e-203 675.9 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family TPR_1 PF00515.28 CDO72496.1 - 4e-19 67.6 0.0 2.1e-05 24.1 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDO72496.1 - 3.7e-17 61.0 1.9 0.00012 21.9 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDO72496.1 - 2.9e-12 45.8 0.2 0.011 15.9 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDO72496.1 - 8.3e-12 45.6 0.8 2.2e-06 28.2 0.1 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDO72496.1 - 1.2e-09 38.1 9.7 0.012 16.3 0.0 5.8 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDO72496.1 - 4.1e-09 36.6 7.2 0.0037 17.5 0.1 4.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CDO72496.1 - 1.7e-08 33.9 0.0 0.4 10.8 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDO72496.1 - 2.4e-08 33.5 2.2 0.00065 19.3 0.1 4.0 2 1 2 4 4 4 2 TPR repeat TPR_17 PF13431.6 CDO72496.1 - 2.8e-07 30.4 0.2 0.016 15.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO72496.1 - 1.9e-06 28.3 4.8 0.016 15.7 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CDO72496.1 - 4.7e-05 22.7 2.5 0.023 13.9 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDO72496.1 - 0.00097 18.9 2.7 2.3 8.2 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDO72496.1 - 0.0013 19.2 2.4 5.5 7.9 0.0 4.8 5 1 0 5 5 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO72496.1 - 0.0087 16.3 0.3 0.025 14.8 0.0 2.0 2 1 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 CDO72496.1 - 0.01 15.3 0.0 0.09 12.2 0.0 2.4 2 1 1 3 3 3 0 Coatomer epsilon subunit TPR_9 PF13371.6 CDO72496.1 - 0.013 15.6 2.0 1.3 9.2 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 CDO72496.1 - 0.024 15.0 0.2 1.5 9.2 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Dimer_Tnp_hAT PF05699.14 CDO72497.1 - 0.0014 18.4 0.0 0.0042 16.8 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region TetR_C_31 PF17940.1 CDO72497.1 - 0.62 10.3 3.1 3.1 8.0 0.1 3.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Fungal_TACC PF12709.7 CDO72498.1 - 0.49 10.9 6.0 0.16 12.4 2.5 2.0 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Takusan PF04822.13 CDO72498.1 - 1.6 8.6 7.2 0.4 10.6 2.2 2.3 2 0 0 2 2 2 0 Takusan DUF3106 PF11304.8 CDO72498.1 - 5.9 7.4 8.7 0.76 10.3 3.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Abhydrolase_4 PF08386.10 CDO72499.1 - 1.2e-12 47.8 0.0 3.6e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 CDO72499.1 - 0.0001 22.0 0.1 0.00056 19.6 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold O-FucT PF10250.9 CDO72500.1 - 5.3e-12 46.1 0.1 2e-05 24.5 0.0 3.4 3 1 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase Abhydrolase_1 PF00561.20 CDO72501.1 - 7.1e-44 150.4 1.2 7.1e-20 71.7 0.1 3.9 4 0 0 4 4 4 3 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 CDO72501.1 - 7.4e-42 141.7 0.0 2.6e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 TAP-like protein Hydrolase_4 PF12146.8 CDO72501.1 - 0.00079 18.8 0.0 29 3.8 0.0 5.2 6 0 0 6 6 6 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CDO72501.1 - 0.044 13.7 0.0 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase PC-Esterase PF13839.6 CDO72502.1 - 3.1e-05 23.9 0.0 0.035 13.8 0.0 2.7 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Esterase_phd PF10503.9 CDO72503.1 - 6.1e-23 81.5 0.7 1.2e-22 80.6 0.7 1.4 1 1 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 CDO72503.1 - 4.6e-14 52.1 8.2 1.9e-13 50.1 8.2 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 CDO72503.1 - 7.5e-10 38.6 0.5 1.5e-09 37.7 0.5 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 CDO72503.1 - 0.0032 16.4 0.0 0.0072 15.2 0.0 1.5 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDO72503.1 - 0.055 13.3 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 CDO72504.1 - 5.7e-20 71.8 0.0 9.4e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 CDO72504.1 - 3.1e-12 46.2 2.1 8.5e-12 44.8 2.1 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 CDO72504.1 - 4.3e-07 29.6 0.4 8.1e-07 28.7 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 CDO72504.1 - 0.028 13.3 0.3 0.028 13.3 0.3 1.9 3 0 0 3 3 3 0 Carboxylesterase family WD40 PF00400.32 CDO72505.1 - 0.047 14.6 2.4 14 6.8 0.1 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat AIRS_C PF02769.22 CDO72506.1 - 4.1e-40 137.5 0.1 2.4e-30 105.7 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CDO72506.1 - 2.5e-31 108.0 0.0 6e-31 106.8 0.0 1.7 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CDO72506.1 - 8.2e-22 77.5 0.0 1.8e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain GATase_5 PF13507.6 CDO72506.1 - 1.6e-14 53.6 0.0 2.7e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS PF00586.24 CDO72506.1 - 0.12 13.0 0.5 0.86 10.3 0.0 2.4 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain Glyco_tranf_2_3 PF13641.6 CDO72507.1 - 2.2e-30 106.3 0.0 3.4e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CDO72507.1 - 2e-09 37.5 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CDO72507.1 - 6.5e-08 32.2 0.0 3.8e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 CDO72507.1 - 0.0081 16.1 5.6 0.015 15.2 5.6 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Sugar_tr PF00083.24 CDO72508.1 - 8.1e-30 104.1 26.3 5.3e-15 55.2 5.5 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDO72508.1 - 4.6e-20 71.9 21.5 8.9e-11 41.3 1.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Carn_acyltransf PF00755.20 CDO72509.1 - 5.3e-207 689.1 0.0 6.1e-207 688.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Dymeclin PF09742.9 CDO72509.1 - 0.18 10.2 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein SKG6 PF08693.10 CDO72511.1 - 0.018 14.5 0.3 0.041 13.3 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 CDO72511.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Bowman-Birk_leg PF00228.20 CDO72511.1 - 0.98 9.9 5.8 1.3 9.4 1.0 2.9 2 0 0 2 2 2 0 Bowman-Birk serine protease inhibitor family Abhydrolase_1 PF00561.20 CDO72512.1 - 6.5e-21 75.1 0.1 8.8e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold ETF PF01012.21 CDO72513.1 - 3.1e-37 128.2 2.8 5.4e-37 127.4 2.8 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CDO72513.1 - 2.2e-33 114.1 0.5 4.5e-33 113.1 0.5 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain E_Pc_C PF06752.12 CDO72513.1 - 0.16 12.0 3.7 0.27 11.3 3.6 1.4 1 1 0 1 1 1 0 Enhancer of Polycomb C-terminus FAD_binding_3 PF01494.19 CDO72514.1 - 3.4e-13 49.6 0.0 2.3e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CDO72514.1 - 0.00012 22.3 0.2 0.00034 20.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDO72514.1 - 0.02 14.5 1.6 0.045 13.3 1.6 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 CDO72514.1 - 0.046 13.0 0.1 0.068 12.4 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 CDO72514.1 - 0.057 12.3 0.4 1.1 8.0 0.1 2.1 1 1 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 CDO72514.1 - 0.082 12.1 0.0 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NUC173 PF08161.12 CDO72515.1 - 4e-58 196.5 2.7 5.1e-55 186.3 0.5 3.5 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.22 CDO72515.1 - 6.5e-05 22.8 0.2 0.83 10.1 0.1 3.8 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 CDO72515.1 - 0.00042 19.0 0.1 2.3 6.7 0.1 3.8 3 1 0 3 3 3 2 Adaptin N terminal region MMS19_C PF12460.8 CDO72515.1 - 0.036 13.2 0.1 0.036 13.2 0.1 5.7 4 3 0 5 5 5 0 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 CDO72515.1 - 0.048 14.2 1.8 70 4.1 0.0 5.3 6 0 0 6 6 6 0 HEAT-like repeat Acyltransferase PF01553.21 CDO72516.1 - 8.4e-08 31.9 0.0 2.6e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Lip_A_acyltrans PF03279.13 CDO72516.1 - 0.075 12.2 0.8 0.19 10.8 0.0 2.0 2 1 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase pPIWI_RE_Z PF18155.1 CDO72516.1 - 0.14 12.0 0.8 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 pPIWI RE three-gene island domain Z Amastin PF07344.11 CDO72517.1 - 0.038 13.9 3.0 0.071 13.0 3.0 1.5 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF998 PF06197.13 CDO72517.1 - 0.05 13.2 9.4 0.07 12.7 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Wzy_C PF04932.15 CDO72517.1 - 0.15 11.7 2.0 0.24 11.0 2.0 1.4 1 1 0 1 1 1 0 O-Antigen ligase SUR7 PF06687.12 CDO72517.1 - 0.9 9.1 5.0 0.62 9.7 3.1 1.6 1 1 0 1 1 1 0 SUR7/PalI family Polysacc_synt_C PF14667.6 CDO72517.1 - 1.8 8.6 8.2 2.8 8.0 8.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain ICMT PF04140.14 CDO72520.1 - 1.1e-13 51.4 0.7 2.4e-12 47.1 0.1 2.7 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO72520.1 - 3.2e-11 43.5 2.7 4.1e-11 43.2 0.3 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO72520.1 - 2.5e-06 26.5 0.6 3.4e-06 26.1 0.6 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Abhydrolase_6 PF12697.7 CDO72522.1 - 3.5e-10 40.9 2.0 4.6e-10 40.5 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDO72522.1 - 0.00016 21.4 0.0 0.00038 20.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Aldo_ket_red PF00248.21 CDO72523.1 - 2.2e-71 240.5 0.0 2.5e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF659 PF04937.15 CDO72524.1 - 1.4e-13 50.9 0.1 2.6e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ADH_zinc_N PF00107.26 CDO72525.1 - 5.2e-20 71.8 0.2 7.5e-20 71.2 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO72525.1 - 3.7e-08 34.5 0.1 8.3e-08 33.4 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CDO72525.1 - 0.0014 18.0 0.2 0.0025 17.2 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 CDO72525.1 - 0.012 16.3 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_3 PF03447.16 CDO72525.1 - 0.013 16.1 0.4 0.036 14.7 0.2 1.8 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain zf-H2C2_2 PF13465.6 CDO72526.1 - 1.1e-07 31.9 6.0 3.1e-06 27.3 1.2 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CDO72526.1 - 0.00034 20.9 1.5 0.00034 20.9 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO72526.1 - 0.01 16.6 1.3 0.01 16.6 1.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger ABC_tran PF00005.27 CDO72527.1 - 3.1e-49 167.0 0.0 1.6e-29 103.2 0.0 4.2 3 2 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CDO72527.1 - 3.6e-14 53.3 0.5 0.00011 22.2 0.2 4.3 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDO72527.1 - 1.2e-13 51.0 0.0 4.1e-05 23.1 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 CDO72527.1 - 1.4e-09 37.7 0.1 2.8e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 CDO72527.1 - 8.8e-07 28.6 0.5 0.069 12.9 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CDO72527.1 - 9.2e-07 29.6 3.6 0.0013 19.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 CDO72527.1 - 5.5e-06 26.4 0.1 0.023 14.8 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 CDO72527.1 - 9.3e-06 25.9 0.0 0.27 11.3 0.1 3.0 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_28 PF13521.6 CDO72527.1 - 2.1e-05 24.8 0.0 0.53 10.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CDO72527.1 - 2.2e-05 24.9 0.2 0.65 10.4 0.0 3.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CDO72527.1 - 2.5e-05 24.6 0.4 0.56 10.5 0.0 3.9 4 1 0 4 4 3 2 AAA domain AAA_18 PF13238.6 CDO72527.1 - 2.7e-05 24.7 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CDO72527.1 - 9e-05 22.4 0.0 0.092 12.7 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 CDO72527.1 - 9.1e-05 22.4 0.1 0.081 12.8 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.6 CDO72527.1 - 0.00018 21.7 0.0 0.09 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CDO72527.1 - 0.00056 19.0 0.4 0.25 10.3 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CDO72527.1 - 0.0018 18.0 0.1 2.1 8.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_13 PF13166.6 CDO72527.1 - 0.0045 15.7 0.0 1.1 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CDO72527.1 - 0.0049 16.6 0.2 4.6 6.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CDO72527.1 - 0.0069 16.8 0.1 3.3 8.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Roc PF08477.13 CDO72527.1 - 0.007 16.6 0.0 6.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HEAT PF02985.22 CDO72527.1 - 0.0076 16.4 8.8 1.5 9.3 0.1 5.5 6 0 0 6 6 5 1 HEAT repeat AAA_14 PF13173.6 CDO72527.1 - 0.011 15.7 0.1 7.9 6.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain HEAT_2 PF13646.6 CDO72527.1 - 0.015 15.6 8.4 1 9.8 0.1 5.1 3 2 3 6 6 5 0 HEAT repeats HEAT_EZ PF13513.6 CDO72527.1 - 0.016 15.7 6.1 0.2 12.2 0.6 4.0 3 1 1 4 4 3 0 HEAT-like repeat IFRD PF05004.13 CDO72527.1 - 0.018 14.2 0.7 0.058 12.5 0.1 2.0 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 CDO72527.1 - 0.027 13.6 0.7 0.15 11.1 0.4 2.0 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal Tudor-knot PF11717.8 CDO72527.1 - 0.027 14.3 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain ATP_bind_1 PF03029.17 CDO72527.1 - 0.028 14.2 0.2 9.5 5.9 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.21 CDO72527.1 - 0.046 13.2 0.0 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Ploopntkinase3 PF18751.1 CDO72527.1 - 0.048 13.6 0.1 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 G-alpha PF00503.20 CDO72527.1 - 0.052 12.7 0.0 0.26 10.4 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_27 PF13514.6 CDO72527.1 - 0.053 13.1 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CDO72527.1 - 0.061 12.5 0.0 10 5.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 CDO72527.1 - 0.075 12.6 0.3 11 5.5 0.2 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 CDO72527.1 - 0.079 12.7 1.6 3.1 7.4 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF3584 PF12128.8 CDO72527.1 - 0.084 10.4 1.5 4.4 4.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_7 PF12775.7 CDO72527.1 - 0.1 12.1 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CDO72527.1 - 0.13 12.2 0.2 37 4.1 0.0 3.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CDO72527.1 - 0.13 11.8 1.0 14 5.2 0.1 3.5 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.9 CDO72527.1 - 0.17 11.7 0.0 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 CDO72527.1 - 0.18 11.9 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Adaptin_N PF01602.20 CDO72527.1 - 0.19 10.3 1.5 0.6 8.6 1.4 1.7 1 1 0 1 1 1 0 Adaptin N terminal region AAA_5 PF07728.14 CDO72527.1 - 0.38 10.8 1.4 20 5.2 0.1 3.4 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SCIMP PF15050.6 CDO72528.1 - 0.13 12.7 1.3 2.1 8.8 0.7 2.5 2 0 0 2 2 2 0 SCIMP protein Glyco_hydro_61 PF03443.14 CDO72529.1 - 7.8e-61 205.6 0.1 7.8e-61 205.6 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Mucin PF01456.17 CDO72529.1 - 0.0054 16.7 12.4 0.0097 15.9 12.4 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein Hamartin PF04388.12 CDO72529.1 - 2.1 6.9 9.6 2.7 6.6 9.6 1.0 1 0 0 1 1 1 0 Hamartin protein EVI2A PF05399.11 CDO72529.1 - 4.5 6.8 9.2 6.4 6.3 9.2 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Homeodomain PF00046.29 CDO72530.1 - 4.1e-17 61.8 4.0 7e-17 61.0 4.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDO72530.1 - 3.2e-05 23.7 0.7 0.00011 22.0 0.1 2.3 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 CDO72530.1 - 0.044 13.6 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Exo84_C PF16528.5 CDO72530.1 - 0.064 13.1 0.4 0.085 12.7 0.4 1.1 1 0 0 1 1 1 0 Exocyst component 84 C-terminal SPX PF03105.19 CDO72530.1 - 7.5 6.4 11.9 11 5.8 11.9 1.3 1 0 0 1 1 1 0 SPX domain Pkinase PF00069.25 CDO72531.1 - 2.8e-17 63.0 0.0 4.4e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO72531.1 - 9.6e-06 25.1 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAP1 PF08601.10 CDO72531.1 - 1.1 8.9 5.2 1.7 8.3 5.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Pkinase PF00069.25 CDO72532.1 - 1.5e-18 67.1 0.0 2.3e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO72532.1 - 1.3e-06 28.0 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CDO72532.1 - 0.11 13.2 0.0 0.28 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Glyco_hydro_18 PF00704.28 CDO72533.1 - 5.1e-84 282.7 0.1 8.2e-84 282.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 CDO72533.1 - 3.4e-13 49.3 13.0 7.4e-13 48.2 13.0 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Phage_CII PF05269.11 CDO72533.1 - 0.11 12.7 0.2 0.26 11.5 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage CII protein GTP_EFTU PF00009.27 CDO72535.1 - 5.2e-18 65.3 0.0 9.3e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CDO72535.1 - 3.4e-05 24.1 0.1 0.00019 21.7 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.17 CDO72535.1 - 0.12 12.1 0.2 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein zf-RING_2 PF13639.6 CDO72536.1 - 2.3e-09 37.4 1.3 3.6e-07 30.4 0.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CDO72536.1 - 3.3e-08 33.7 0.6 3.1e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CDO72536.1 - 1.5e-07 31.1 0.1 0.00019 21.1 0.0 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDO72536.1 - 2.6e-07 30.3 4.7 7.9e-07 28.8 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO72536.1 - 2.3e-06 27.3 0.2 2.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO72536.1 - 4.8e-05 23.3 1.7 0.0031 17.5 0.3 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDO72536.1 - 0.00018 21.4 0.6 0.00047 20.1 0.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDO72536.1 - 0.00035 20.4 0.5 0.0008 19.2 0.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDO72536.1 - 0.00066 19.7 0.3 0.0032 17.5 0.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 CDO72536.1 - 0.029 14.7 0.8 0.056 13.8 0.8 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 CDO72536.1 - 0.031 14.1 2.2 0.049 13.5 0.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CDO72536.1 - 0.1 12.4 0.1 0.1 12.4 0.1 1.6 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 CDO72536.1 - 0.17 11.9 1.5 0.59 10.2 1.3 2.0 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4_4 PF15227.6 CDO72536.1 - 0.21 11.8 1.6 0.56 10.4 0.5 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 CDO72536.1 - 0.22 11.2 3.8 0.1 12.2 1.1 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 CDO72536.1 - 0.38 10.7 1.5 0.95 9.4 1.5 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 CDO72536.1 - 0.54 10.5 4.7 0.85 9.8 1.8 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain Peroxidase_ext PF11895.8 CDO72537.1 - 6.6e-31 106.1 4.8 1.5e-30 104.9 1.6 2.4 2 0 0 2 2 2 1 Fungal peroxidase extension region peroxidase PF00141.23 CDO72537.1 - 2.9e-29 102.4 0.0 5e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 CDO72538.1 - 1.9e-27 95.0 1.2 4.1e-27 93.9 1.2 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 CDO72538.1 - 8.2e-24 84.6 0.0 1.6e-23 83.6 0.0 1.5 1 1 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 CDO72539.1 - 1.5e-26 92.1 1.2 3.9e-26 90.8 1.2 1.7 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 CDO72539.1 - 8.5e-21 74.7 0.1 2.1e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 Peroxidase Peroxidase_ext PF11895.8 CDO72540.1 - 2.5e-25 88.2 0.1 4.6e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 CDO72540.1 - 2.2e-21 76.6 0.0 3e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Peptidase_C1_2 PF03051.15 CDO72541.1 - 1.2e-158 528.6 0.0 1.4e-158 528.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 CDO72541.1 - 7.6e-07 29.4 0.0 0.018 15.1 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.13 CDO72541.1 - 0.0064 15.7 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Phage portal protein, lambda family DUF4218 PF13960.6 CDO72542.1 - 0.00042 19.9 0.0 0.00085 18.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) NiFe-hyd_HybE PF11939.8 CDO72542.1 - 0.023 14.6 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE Transposase_21 PF02992.14 CDO72543.1 - 4.1e-11 42.5 0.0 3.3e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.12 CDO72543.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) AvrLm4-7 PF18661.1 CDO72545.1 - 0.0058 17.6 2.5 0.22 12.6 0.1 2.5 2 0 0 2 2 2 2 Avirulence Effector AvrLm4-7 rve PF00665.26 CDO72546.1 - 8.8e-07 29.1 0.0 3.7e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CDO72546.1 - 0.061 13.6 0.1 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 DDE domain Integrase_H2C2 PF17921.1 CDO72546.1 - 0.1 12.7 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain zf-CCHC PF00098.23 CDO72547.1 - 1.4e-05 25.0 2.1 2.5e-05 24.2 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 CDO72547.1 - 0.0018 18.0 2.2 0.0033 17.1 2.2 1.4 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_6 PF15288.6 CDO72547.1 - 0.02 14.7 0.3 0.041 13.7 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDO72547.1 - 0.037 13.7 0.5 0.065 13.0 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle Pkinase_fungal PF17667.1 CDO72548.1 - 4.8e-55 187.0 0.0 8.2e-31 107.2 0.0 2.3 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 CDO72548.1 - 0.015 15.3 0.1 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CDO72548.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase ARD PF03079.14 CDO72549.1 - 2.3e-38 131.9 0.0 3.2e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CDO72549.1 - 2.7e-10 39.8 0.1 5.1e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CDO72549.1 - 1.1e-06 28.6 0.3 1.7e-06 28.0 0.3 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Sugar_tr PF00083.24 CDO72549.1 - 4.3e-05 22.6 0.1 5.6e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Lyx_isomer PF07385.12 CDO72549.1 - 0.024 13.9 0.1 1.3 8.2 0.0 2.1 1 1 1 2 2 2 0 D-lyxose isomerase Cupin_8 PF13621.6 CDO72549.1 - 0.03 14.0 0.1 0.055 13.2 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain Cupin_1 PF00190.22 CDO72549.1 - 0.058 13.0 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Cupin 3-HAO PF06052.12 CDO72549.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Pirin PF02678.16 CDO72549.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Pirin WD40 PF00400.32 CDO72551.1 - 1.2e-33 114.6 26.6 4.1e-07 30.6 0.0 10.9 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO72551.1 - 7.6e-14 51.8 0.2 0.033 14.5 0.0 7.2 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 CDO72551.1 - 1.6e-11 44.4 0.0 7.7e-11 42.2 0.0 2.2 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 CDO72551.1 - 4.5e-05 23.9 0.1 0.00019 21.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain WD40_like PF17005.5 CDO72551.1 - 0.0002 20.8 0.0 2.1 7.6 0.0 3.9 4 0 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 CDO72551.1 - 0.0005 19.1 0.1 5.7 5.8 0.0 3.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_22 PF13401.6 CDO72551.1 - 0.00075 19.8 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain PD40 PF07676.12 CDO72551.1 - 0.0016 18.3 2.4 4.2 7.4 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DUF296 PF03479.15 CDO72551.1 - 0.021 15.2 0.0 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 Plants and Prokaryotes Conserved (PCC) domain NB-ARC PF00931.22 CDO72551.1 - 0.031 13.5 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Cytochrom_D1 PF02239.16 CDO72551.1 - 0.14 10.7 0.1 1.8 7.0 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain KAP_NTPase PF07693.14 CDO72551.1 - 0.2 10.8 0.1 0.38 10.0 0.1 1.4 1 0 0 1 1 1 0 KAP family P-loop domain WD40 PF00400.32 CDO72552.1 - 7.5e-39 131.0 34.7 8.1e-08 32.8 0.1 11.5 13 0 0 13 13 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO72552.1 - 1.7e-18 66.7 5.0 0.0013 19.0 0.0 8.1 4 1 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 CDO72552.1 - 5.2e-10 39.5 0.1 1.2e-09 38.3 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CDO72552.1 - 2.8e-06 27.8 1.0 8.4e-05 23.0 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CDO72552.1 - 4.3e-05 23.8 0.0 0.00013 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Ge1_WD40 PF16529.5 CDO72552.1 - 0.0011 18.1 0.4 0.34 9.8 0.1 3.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CDO72552.1 - 0.0036 16.0 0.2 0.82 8.2 0.1 3.0 3 0 0 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 CDO72552.1 - 0.026 13.9 0.0 10 5.3 0.0 3.6 2 1 2 4 4 4 0 WD40-like domain NB-ARC PF00931.22 CDO72552.1 - 0.038 13.2 0.0 0.082 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Coatomer_WDAD PF04053.14 CDO72552.1 - 0.058 12.4 0.0 0.47 9.4 0.0 2.4 4 0 0 4 4 4 0 Coatomer WD associated region AAA_30 PF13604.6 CDO72552.1 - 0.06 13.1 0.0 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CDO72552.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Plavaka PF18759.1 CDO72553.1 - 5.1e-106 354.6 0.1 7.3e-106 354.0 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_6 PF13912.6 CDO72553.1 - 0.0024 17.8 0.8 0.0069 16.4 0.8 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 CDO72553.1 - 0.0045 17.3 0.4 0.017 15.5 0.4 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CDO72553.1 - 0.034 15.0 0.6 0.65 11.0 1.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDO72553.1 - 0.096 13.0 1.0 0.25 11.7 0.6 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CDO72553.1 - 2.9 8.5 6.3 0.81 10.3 1.5 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Cnd1_N PF12922.7 CDO72557.1 - 3.4e-51 173.4 0.5 7.1e-51 172.3 0.5 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term DehI PF10778.9 CDO72557.1 - 0.0078 16.4 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Halocarboxylic acid dehydrogenase DehI FKS1_dom1 PF14288.6 CDO72557.1 - 0.033 14.5 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Ald_Xan_dh_C2 PF02738.18 CDO72557.1 - 0.048 12.1 0.0 0.091 11.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase RELT PF12606.8 CDO72557.1 - 1.6 7.7 5.5 0.44 9.6 1.1 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Transposase_21 PF02992.14 CDO72558.1 - 3.2e-05 23.3 0.1 8.5e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 WD40 PF00400.32 CDO72559.1 - 3.9e-28 97.1 38.1 4.2e-06 27.4 0.2 11.6 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO72559.1 - 6e-14 52.1 4.2 0.069 13.4 0.1 8.2 5 2 6 11 11 10 5 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 CDO72559.1 - 1.7e-10 41.0 0.0 1e-09 38.5 0.0 2.3 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 CDO72559.1 - 6.6e-07 29.9 0.2 5e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDO72559.1 - 0.0075 16.5 0.0 0.027 14.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 CDO72559.1 - 0.0083 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain NB-ARC PF00931.22 CDO72559.1 - 0.0095 15.2 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Nup160 PF11715.8 CDO72559.1 - 0.011 14.5 0.3 3.4 6.2 0.2 3.3 4 0 0 4 4 4 0 Nucleoporin Nup120/160 PD40 PF07676.12 CDO72559.1 - 0.023 14.6 3.9 0.088 12.8 0.1 3.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 CDO72559.1 - 0.049 12.7 0.0 8.6 5.3 0.0 2.4 2 0 0 2 2 2 0 Coatomer WD associated region DUF5018 PF16410.5 CDO72559.1 - 0.15 10.7 0.0 0.47 9.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5018) AAA PF00004.29 CDO72559.1 - 0.2 12.1 0.0 3.3 8.1 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3337 PF11816.8 CDO72560.1 - 1e-47 162.2 0.0 1.6e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 CDO72560.1 - 1.1e-23 83.1 3.6 2.9e-06 27.9 0.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CDO72560.1 - 0.00057 18.9 0.0 0.0022 17.0 0.0 1.8 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 CDO72560.1 - 0.0057 16.9 0.1 0.17 12.2 0.0 3.1 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain RAWUL PF16207.5 CDO72560.1 - 0.043 14.5 0.0 0.083 13.6 0.0 1.4 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Nup160 PF11715.8 CDO72560.1 - 0.052 12.2 0.1 0.92 8.1 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Squash PF00299.18 CDO72561.1 - 0.046 13.8 0.2 0.086 12.9 0.2 1.5 1 0 0 1 1 1 0 Squash family serine protease inhibitor DX PF01666.17 CDO72562.1 - 0.091 13.2 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 DX module DX PF01666.17 CDO72563.1 - 0.061 13.8 0.0 0.091 13.2 0.0 1.2 1 0 0 1 1 1 0 DX module Pkinase_fungal PF17667.1 CDO72564.1 - 2e-09 36.7 0.2 4e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase NACHT PF05729.12 CDO72564.1 - 0.023 14.6 0.2 0.05 13.5 0.2 1.5 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 CDO72564.1 - 0.044 13.0 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain Phage_min_cap2 PF06152.11 CDO72564.1 - 0.09 11.7 1.3 0.23 10.3 1.1 1.6 2 0 0 2 2 2 0 Phage minor capsid protein 2 PRC2_HTH_1 PF18118.1 CDO72564.1 - 0.11 13.3 0.2 0.23 12.3 0.2 1.4 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Pkinase_fungal PF17667.1 CDO72565.1 - 1.4e-51 175.6 0.0 2.1e-28 99.2 0.0 2.4 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 CDO72565.1 - 0.0092 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CDO72565.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Sugar_tr PF00083.24 CDO72566.1 - 4.5e-27 95.0 8.0 8.7e-14 51.2 3.2 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 CDO72566.1 - 0.0037 16.2 6.9 0.56 9.1 5.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily LamB_YcsF PF03746.16 CDO72567.1 - 2.4e-75 253.3 0.0 2.7e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Pkinase_fungal PF17667.1 CDO72568.1 - 7.6e-52 176.5 0.0 6.6e-29 100.9 0.0 2.8 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 CDO72568.1 - 0.013 15.5 0.7 0.022 14.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CDO72568.1 - 0.019 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase PRC2_HTH_1 PF18118.1 CDO72568.1 - 0.04 14.7 0.6 0.092 13.6 0.6 1.5 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain LamB_YcsF PF03746.16 CDO72569.1 - 1.2e-09 38.2 0.0 1.4e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Pkinase_fungal PF17667.1 CDO72570.1 - 5.2e-51 173.7 0.0 3.8e-29 101.7 0.0 2.4 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 CDO72570.1 - 0.0084 16.1 0.3 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CDO72570.1 - 0.02 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Sugar_tr PF00083.24 CDO72571.1 - 8.7e-06 24.8 1.3 0.0016 17.4 0.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter TMEM100 PF16311.5 CDO72571.1 - 0.19 11.3 1.0 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 100 FAD_binding_3 PF01494.19 CDO72572.1 - 1.1e-20 74.2 0.0 2.6e-20 73.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CDO72572.1 - 7.5e-07 29.3 1.1 1.9e-06 28.0 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CDO72572.1 - 1.1e-06 27.8 1.2 0.0013 17.7 1.2 2.4 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 CDO72572.1 - 2.2e-06 27.1 0.3 6.2e-06 25.7 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CDO72572.1 - 0.00024 20.3 1.9 0.15 11.0 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 CDO72572.1 - 0.0013 17.9 3.5 0.0021 17.2 3.5 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CDO72572.1 - 0.0014 18.2 1.8 0.0031 17.1 1.8 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDO72572.1 - 0.0043 16.3 0.4 0.0084 15.4 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 CDO72572.1 - 0.0057 16.0 1.0 0.017 14.4 0.5 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase SE PF08491.10 CDO72572.1 - 0.0075 15.4 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_oxidored PF12831.7 CDO72572.1 - 0.0088 15.4 0.8 0.012 15.0 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CDO72572.1 - 0.011 14.5 2.0 0.022 13.5 2.0 1.4 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 CDO72572.1 - 0.011 16.3 0.5 0.031 14.8 0.3 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDO72572.1 - 0.069 12.2 3.3 0.11 11.6 3.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CDO72572.1 - 0.1 11.9 0.6 0.18 11.1 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 CDO72572.1 - 0.39 10.4 1.5 0.67 9.6 1.5 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3533 PF12051.8 CDO72573.1 - 7.3e-65 219.3 12.8 8.1e-65 219.2 12.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) MFS_1 PF07690.16 CDO72574.1 - 4.2e-28 98.3 24.5 6.2e-28 97.7 24.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 CDO72575.1 - 1.8e-29 102.8 31.1 2.5e-29 102.3 31.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.21 CDO72577.1 - 0.016 14.7 0.0 0.034 13.6 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 16 COX7C PF02935.16 CDO72578.1 - 3e-12 46.6 0.7 4e-12 46.2 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Mif2_N PF15624.6 CDO72579.1 - 0.019 15.7 1.3 0.019 15.7 1.3 2.4 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Epimerase PF01370.21 CDO72580.1 - 4.7e-17 62.2 0.0 9.2e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CDO72580.1 - 2.1e-14 53.4 0.0 2.6e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 CDO72580.1 - 5.7e-13 48.5 0.0 9.3e-12 44.5 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CDO72580.1 - 1.2e-10 41.4 0.2 5.9e-07 29.2 0.0 2.6 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CDO72580.1 - 8.5e-09 35.6 0.7 0.00024 21.0 0.0 2.3 2 0 0 2 2 2 2 NAD(P)H-binding KR PF08659.10 CDO72580.1 - 0.0003 20.8 2.2 0.0036 17.2 2.2 2.2 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 CDO72580.1 - 0.0032 17.0 0.0 0.012 15.2 0.1 1.9 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 CDO72580.1 - 0.0073 15.8 0.7 0.02 14.4 0.0 2.0 3 0 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 CDO72580.1 - 0.058 12.5 0.7 1.4 7.9 0.7 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 CDO72581.1 - 4e-43 147.6 0.0 2.9e-41 141.6 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 CDO72581.1 - 6.8e-15 55.4 0.0 1.4e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CDO72581.1 - 6.5e-05 22.5 0.0 0.00013 21.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO72581.1 - 0.0024 16.9 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CDO72581.1 - 0.041 14.0 0.0 0.092 12.9 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 CDO72581.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 CDO72581.1 - 0.14 11.6 0.2 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Glyco_hydro_28 PF00295.17 CDO72584.1 - 1.7e-48 165.4 15.1 1.9e-25 89.6 3.8 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 Cadherin_5 PF17892.1 CDO72584.1 - 0.0022 17.9 0.8 0.0081 16.1 0.1 2.3 2 0 0 2 2 2 1 Cadherin-like domain F-box-like PF12937.7 CDO72587.1 - 4.8e-07 29.6 0.8 1.4e-06 28.1 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDO72587.1 - 0.00012 21.9 0.3 0.0029 17.4 0.0 2.8 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 CDO72587.1 - 0.023 15.1 0.4 4.2 7.9 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Evr1_Alr PF04777.13 CDO72588.1 - 4.3e-21 75.3 0.1 1.5e-20 73.6 0.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family TP_methylase PF00590.20 CDO72588.1 - 1.8e-12 47.7 0.0 2.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases tRNA-synt_2 PF00152.20 CDO72589.1 - 4e-89 298.8 0.0 5.3e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDO72589.1 - 1.5e-12 47.3 0.2 6.1e-12 45.4 0.2 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 CDO72589.1 - 0.2 11.7 0.1 0.73 9.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) Pkinase PF00069.25 CDO72593.1 - 3.6e-36 124.9 0.0 1.4e-23 83.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO72593.1 - 1.6e-19 70.2 0.0 2e-11 43.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase DUF5521 PF17659.1 CDO72593.1 - 0.4 8.5 1.6 0.53 8.1 1.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DDE_3 PF13358.6 CDO72595.1 - 8.4e-17 61.3 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CDO72595.1 - 2.9e-09 37.0 4.9 5.6e-07 29.7 2.1 3.1 3 0 0 3 3 3 1 Transposase HTH_38 PF13936.6 CDO72595.1 - 1.1e-06 28.2 0.1 3.1e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CDO72595.1 - 7e-06 25.7 0.1 5.1e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CDO72595.1 - 5.2e-05 23.3 0.0 5.2e-05 23.3 0.0 3.0 4 0 0 4 4 3 1 Helix-turn-helix domain HTH_IclR PF09339.10 CDO72595.1 - 0.00035 20.3 0.0 0.00088 19.0 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.12 CDO72595.1 - 0.00066 19.6 0.1 0.007 16.3 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.6 CDO72595.1 - 0.0027 17.7 2.6 0.0034 17.4 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_r4 PF04545.16 CDO72595.1 - 0.003 17.1 1.0 0.0053 16.2 0.0 1.9 2 0 0 2 2 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 CDO72595.1 - 0.0046 16.3 0.7 0.023 14.1 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_Crp_2 PF13545.6 CDO72595.1 - 0.0059 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_AraC PF00165.23 CDO72595.1 - 0.0087 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family MarR_2 PF12802.7 CDO72595.1 - 0.0089 15.9 0.7 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 MarR family GntR PF00392.21 CDO72595.1 - 0.02 14.5 0.0 0.062 13.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.15 CDO72595.1 - 0.025 14.6 0.1 2.4 8.3 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MarR PF01047.22 CDO72595.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 CDO72595.1 - 0.13 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.6 CDO72595.1 - 0.15 12.0 2.3 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Phage_NinH PF06322.11 CDO72595.1 - 0.18 11.7 1.9 0.38 10.7 0.1 2.1 2 0 0 2 2 2 0 Phage NinH protein SNF2_N PF00176.23 CDO72596.1 - 4.7e-64 216.3 0.3 7.6e-64 215.6 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDO72596.1 - 1.6e-17 63.8 0.1 1.2e-15 57.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO72596.1 - 1.5e-10 41.4 0.0 4.2e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDO72596.1 - 5.7e-05 22.9 0.0 0.00028 20.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ArsB PF02040.15 CDO72597.1 - 2.1e-12 47.1 15.6 1.9e-07 30.8 1.9 3.2 2 1 0 2 2 2 2 Arsenical pump membrane protein DUF1003 PF06210.11 CDO72597.1 - 0.089 12.9 2.5 0.41 10.8 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Gate PF07670.14 CDO72597.1 - 0.29 11.4 5.2 1.7 9.0 1.6 3.5 3 0 0 3 3 3 0 Nucleoside recognition Mito_carr PF00153.27 CDO72599.1 - 4.2e-34 116.3 0.1 1e-17 63.8 0.0 2.4 2 1 0 2 2 2 2 Mitochondrial carrier protein Peptidase_S8 PF00082.22 CDO72604.1 - 1.1e-21 77.4 6.0 1.7e-21 76.8 6.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CDO72604.1 - 3e-16 59.8 0.1 5.6e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sulfate_transp PF00916.20 CDO72606.1 - 4.1e-43 147.6 1.5 5.8e-43 147.1 1.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDO72606.1 - 4.9e-10 39.1 0.0 3.2e-06 26.7 0.0 3.2 2 1 0 2 2 2 2 STAS domain FUSC-like PF12805.7 CDO72606.1 - 2.1 7.4 4.1 5.3 6.0 4.1 1.6 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Plavaka PF18759.1 CDO72608.1 - 3.8e-44 151.2 0.0 6e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF2490 PF10677.9 CDO72608.1 - 0.022 14.7 0.2 0.072 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2490) GPI-anchored PF10342.9 CDO72610.1 - 0.0019 18.9 0.0 0.0031 18.2 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 CDO72610.1 - 0.11 12.3 0.3 0.15 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Sld7_C PF18596.1 CDO72612.1 - 1e-07 32.0 0.1 1.8e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain SGS PF05002.15 CDO72612.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 SGS domain Cyclase PF04199.13 CDO72613.1 - 4.6e-62 208.3 1.4 1.1e-33 116.3 0.2 2.2 2 0 0 2 2 2 2 Putative cyclase Glyco_hydro_31 PF01055.26 CDO72614.1 - 1.1e-139 466.5 4.2 1.1e-139 466.5 4.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CDO72614.1 - 7e-20 71.1 0.3 2.2e-19 69.5 0.3 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 CDO72614.1 - 5.5e-06 26.6 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Helicase_C_2 PF13307.6 CDO72617.1 - 4.4e-53 179.9 0.0 8.9e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CDO72617.1 - 9.8e-40 136.0 0.1 9.2e-37 126.3 0.1 2.6 1 1 0 1 1 1 1 DEAD_2 DEAD PF00270.29 CDO72617.1 - 0.0059 16.4 0.1 0.041 13.6 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_25 PF13481.6 CDO72617.1 - 0.022 14.3 0.4 0.056 13.0 0.4 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDO72617.1 - 0.034 13.6 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 CDO72617.1 - 0.042 13.9 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ThrE PF06738.12 CDO72617.1 - 0.18 11.2 0.3 0.31 10.4 0.3 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter Mito_carr PF00153.27 CDO72618.1 - 2.4e-48 162.0 0.1 2.2e-16 59.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HTH_28 PF13518.6 CDO72618.1 - 0.053 13.7 0.5 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain 3HCDH_N PF02737.18 CDO72619.1 - 3.1e-50 170.5 3.7 2.5e-49 167.6 3.7 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CDO72619.1 - 8.1e-22 77.7 0.0 2.4e-21 76.1 0.0 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CDO72619.1 - 0.006 16.8 0.3 0.015 15.5 0.3 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase polyprenyl_synt PF00348.17 CDO72621.1 - 1.9e-16 59.9 0.0 2.3e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Gcn1_N PF12074.8 CDO72622.1 - 2.2e-84 283.8 0.2 2.2e-84 283.8 0.2 4.4 5 0 0 5 5 5 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 CDO72622.1 - 8.4e-35 115.8 33.0 0.077 13.3 0.0 22.2 25 0 0 25 25 22 8 HEAT repeat HEAT_EZ PF13513.6 CDO72622.1 - 1.4e-32 111.6 25.5 0.00038 20.9 0.1 16.7 16 2 3 19 19 16 6 HEAT-like repeat HEAT_2 PF13646.6 CDO72622.1 - 7.6e-25 87.1 32.4 4.7e-05 23.7 0.1 13.8 13 2 4 17 17 16 7 HEAT repeats Cnd1 PF12717.7 CDO72622.1 - 3.1e-13 50.1 0.0 0.55 10.3 0.0 9.7 6 3 4 10 10 10 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CDO72622.1 - 3.8e-10 39.7 0.0 0.0089 15.6 0.0 6.2 5 2 0 7 7 7 2 CLASP N terminal IFRD PF05004.13 CDO72622.1 - 2.1e-08 33.6 9.1 0.22 10.6 0.0 7.3 5 2 1 7 7 7 3 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 CDO72622.1 - 1.5e-06 27.1 2.3 0.23 10.0 0.1 7.0 7 3 0 7 7 7 2 Adaptin N terminal region Tti2 PF10521.9 CDO72622.1 - 4e-06 26.6 0.1 0.28 10.7 0.0 5.3 5 0 0 5 5 5 1 Tti2 family Ecm29 PF13001.7 CDO72622.1 - 2.8e-05 23.0 1.2 2.5 6.7 0.0 5.7 6 1 1 7 7 7 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 CDO72622.1 - 0.0001 22.8 0.0 20 5.9 0.0 6.5 5 2 3 8 8 7 0 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.7 CDO72622.1 - 0.00065 19.9 0.4 4 7.9 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion UNC45-central PF11701.8 CDO72622.1 - 0.0027 17.7 0.0 0.032 14.2 0.0 3.0 2 0 0 2 2 1 1 Myosin-binding striated muscle assembly central DUF3437 PF11919.8 CDO72622.1 - 0.0051 16.7 3.9 3.8 7.5 0.0 6.0 7 0 0 7 7 7 1 Domain of unknown function (DUF3437) NUC173 PF08161.12 CDO72622.1 - 0.014 15.1 0.3 24 4.5 0.1 4.6 3 1 1 4 4 4 0 NUC173 domain Ipi1_N PF12333.8 CDO72622.1 - 0.052 14.1 0.7 15 6.2 0.1 5.1 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.23 CDO72622.1 - 0.14 12.2 6.4 6.2 7.0 0.0 5.8 6 0 0 6 6 4 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 CDO72622.1 - 3.9 6.5 21.5 14 4.7 0.1 7.6 9 2 1 10 10 10 0 RNAPII transcription regulator C-terminal MFS_1 PF07690.16 CDO72623.1 - 6.9e-44 150.2 50.4 2.7e-40 138.4 53.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CDO72623.1 - 1.2e-07 30.6 12.5 1.2e-07 30.6 12.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CDO72623.1 - 7e-06 25.2 16.5 7e-06 25.2 16.5 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter HMG_box PF00505.19 CDO72624.1 - 0.00033 21.0 0.0 0.0011 19.4 0.0 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box GPI-anchored PF10342.9 CDO72625.1 - 0.0013 19.4 0.0 0.0018 19.0 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 CDO72625.1 - 0.081 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) YCII PF03795.14 CDO72626.1 - 3.4e-10 40.2 0.0 4.2e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Cu-oxidase_3 PF07732.15 CDO72627.1 - 0.0081 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase DNA_pol_B_thumb PF14791.6 CDO72628.1 - 5.8e-21 74.4 0.1 1.3e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 CDO72628.1 - 1e-17 64.4 0.0 2e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 CDO72628.1 - 9.6e-11 41.9 0.0 3.1e-10 40.3 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CDO72628.1 - 3e-09 36.6 0.0 1e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda BRCT_2 PF16589.5 CDO72628.1 - 2.1e-05 24.8 0.0 4.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 CDO72628.1 - 0.0048 17.5 0.0 0.017 15.7 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.8 CDO72628.1 - 0.006 16.8 0.0 0.049 13.9 0.0 2.3 2 0 0 2 2 2 1 Pathogenicity locus FAD-oxidase_C PF02913.19 CDO72629.1 - 0.35 10.5 2.9 0.57 9.8 2.9 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain FLILHELTA PF10306.9 CDO72630.1 - 1.4e-10 41.4 0.0 3.1e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA GPI-anchored PF10342.9 CDO72631.1 - 0.0023 18.6 0.0 0.0032 18.2 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 CDO72631.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DNA_pol_B_thumb PF14791.6 CDO72632.1 - 2.4e-21 75.7 0.1 5.8e-21 74.4 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 CDO72632.1 - 1.3e-10 41.4 0.0 6.4e-10 39.3 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CDO72632.1 - 3.9e-10 39.4 0.0 2.2e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 CDO72632.1 - 2.7e-08 34.0 0.0 4.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm Cdd1 PF11731.8 CDO72632.1 - 0.00099 19.3 0.0 0.009 16.2 0.0 2.3 2 0 0 2 2 2 1 Pathogenicity locus HHH_5 PF14520.6 CDO72632.1 - 0.0016 19.0 0.0 0.0062 17.1 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain IMS_HHH PF11798.8 CDO72632.1 - 0.088 13.2 0.0 2.3 8.7 0.0 2.7 2 0 0 2 2 2 0 IMS family HHH motif Plavaka PF18759.1 CDO72633.1 - 1.7e-125 418.6 0.0 3.1e-125 417.7 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase Glyco_hydro_cc PF11790.8 CDO72633.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core zf-C2H2_9 PF16293.5 CDO72633.1 - 0.99 9.3 3.4 0.34 10.8 0.1 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) PRKG1_interact PF15898.5 CDO72634.1 - 0.36 11.7 7.6 0.93 10.4 7.6 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4407 PF14362.6 CDO72634.1 - 0.59 9.4 6.6 1.2 8.4 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 CDO72634.1 - 0.64 7.9 4.6 0.92 7.3 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paramyxo_ncap PF00973.19 CDO72634.1 - 0.84 8.5 10.0 1.4 7.7 10.0 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein EMC3_TMCO1 PF01956.16 CDO72634.1 - 3.7 7.3 5.8 27 4.5 5.5 2.0 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like FAM60A PF15396.6 CDO72634.1 - 4 7.4 10.5 6.9 6.6 10.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A PIEZO PF15917.5 CDO72634.1 - 6.2 6.2 8.6 11 5.5 8.6 1.3 1 0 0 1 1 1 0 Piezo Macoilin PF09726.9 CDO72634.1 - 9.8 4.6 11.8 13 4.2 11.8 1.1 1 0 0 1 1 1 0 Macoilin family Retrotran_gag_2 PF14223.6 CDO72635.1 - 2.8e-18 65.9 0.0 3.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CDO72635.1 - 7e-05 22.4 1.3 0.00011 21.8 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) DDE_3 PF13358.6 CDO72637.1 - 9.3e-09 35.2 0.0 2.3e-05 24.2 0.0 3.4 3 0 0 3 3 3 2 DDE superfamily endonuclease Acyl-CoA_dh_1 PF00441.24 CDO72638.1 - 4.5e-26 91.8 0.2 6.3e-26 91.4 0.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDO72638.1 - 4.3e-21 74.9 0.0 8.8e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CDO72638.1 - 3.9e-06 27.5 0.0 7.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CDO72638.1 - 2.5e-05 24.6 0.3 0.00017 21.9 0.3 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fez1 PF06818.15 CDO72639.1 - 0.00018 22.0 4.7 0.00038 21.0 4.7 1.4 1 0 0 1 1 1 1 Fez1 Med9 PF07544.13 CDO72639.1 - 0.0026 17.8 2.2 0.027 14.6 2.2 2.2 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 ERM PF00769.19 CDO72639.1 - 0.0064 16.3 10.8 0.011 15.5 10.8 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Allexi_40kDa PF05549.11 CDO72639.1 - 0.0085 15.6 1.7 0.013 15.0 1.7 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein COG5 PF10392.9 CDO72639.1 - 0.013 15.6 1.2 0.024 14.8 1.2 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 SPESP1 PF15754.5 CDO72639.1 - 0.026 13.7 1.2 0.04 13.1 1.2 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF4449 PF14613.6 CDO72639.1 - 0.06 13.5 1.7 0.13 12.4 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Spc7 PF08317.11 CDO72639.1 - 0.067 12.1 8.1 0.1 11.5 8.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Cnn_1N PF07989.11 CDO72639.1 - 0.1 12.8 5.9 0.23 11.7 5.9 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 FapA PF03961.13 CDO72639.1 - 0.16 10.5 2.4 0.22 10.1 2.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prefoldin PF02996.17 CDO72639.1 - 1.3 9.0 8.6 0.44 10.5 2.7 2.2 2 0 0 2 2 2 0 Prefoldin subunit Swi5 PF07061.11 CDO72639.1 - 1.4 9.1 6.0 0.66 10.1 1.9 2.3 2 0 0 2 2 2 0 Swi5 DUF4140 PF13600.6 CDO72639.1 - 1.8 9.1 8.8 7 7.2 3.7 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 CDO72639.1 - 2.4 8.2 10.4 9.7 6.2 10.4 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Snapin_Pallidin PF14712.6 CDO72639.1 - 3.5 8.1 8.9 1.8 9.0 0.2 2.7 2 1 0 3 3 2 0 Snapin/Pallidin APG6_N PF17675.1 CDO72639.1 - 3.6 8.1 14.2 10 6.6 14.2 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region TSC22 PF01166.18 CDO72639.1 - 5.1 7.5 7.4 18 5.7 0.5 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 CDO72639.1 - 5.3 7.7 10.2 3.5 8.3 2.7 2.7 2 1 1 3 3 3 0 Initiation control protein YabA YCII PF03795.14 CDO72640.1 - 2.3e-08 34.3 0.0 2.8e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Fe-S_biosyn PF01521.20 CDO72641.1 - 9e-13 48.4 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis bZIP_1 PF00170.21 CDO72645.1 - 1.5e-08 34.6 11.4 1.5e-08 34.6 11.4 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CDO72645.1 - 3.8e-06 26.9 12.4 3.8e-06 26.9 12.4 2.6 2 1 0 2 2 2 1 Basic region leucine zipper KIAA1430 PF13879.6 CDO72645.1 - 0.49 11.2 6.6 1.1 10.1 6.6 1.6 1 0 0 1 1 1 0 KIAA1430 homologue TFIIA PF03153.13 CDO72645.1 - 2 8.4 17.3 2.5 8.0 17.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FapA PF03961.13 CDO72645.1 - 2.9 6.4 5.7 4.3 5.8 5.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ABC_membrane PF00664.23 CDO72646.1 - 1.3e-53 182.4 3.6 1.7e-53 182.0 3.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDO72646.1 - 2.8e-31 108.9 0.0 7.7e-31 107.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CDO72646.1 - 2.5e-06 27.1 0.1 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CDO72646.1 - 0.00031 20.1 0.0 0.00095 18.5 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 CDO72646.1 - 0.00064 20.1 1.3 0.0053 17.1 0.4 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CDO72646.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 CDO72646.1 - 0.048 13.7 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 CDO72646.1 - 0.059 13.3 0.4 0.25 11.3 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase AAA_21 PF13304.6 CDO72646.1 - 0.076 12.8 0.2 1.5 8.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CDO72646.1 - 0.17 12.1 0.4 1.4 9.2 0.4 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit YCII PF03795.14 CDO72647.1 - 3.7e-09 36.9 0.0 5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.14 CDO72648.1 - 8e-08 32.6 0.0 1.1e-07 32.2 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DUF4288 PF14119.6 CDO72648.1 - 0.11 12.9 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) ARGLU PF15346.6 CDO72649.1 - 0.1 12.5 3.8 0.15 11.9 3.8 1.4 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 LRV PF01816.17 CDO72649.1 - 0.64 10.5 2.8 30 5.3 2.8 2.3 1 1 0 1 1 1 0 Leucine rich repeat variant CTP_transf_like PF01467.26 CDO72652.1 - 9e-27 94.0 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Amidohydro_1 PF01979.20 CDO72653.1 - 2.4e-17 63.3 0.0 2.7e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDO72653.1 - 4.9e-11 42.8 0.0 5.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CDO72654.1 - 0.00045 19.6 0.0 0.00053 19.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Kri1_C PF12936.7 CDO72656.1 - 4.4e-27 94.1 0.1 4.4e-27 94.1 0.1 4.9 6 0 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.12 CDO72656.1 - 5e-25 88.0 8.2 5e-25 88.0 8.2 6.4 3 2 3 6 6 6 1 KRI1-like family F-box PF00646.33 CDO72657.1 - 0.0049 16.7 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain B5 PF03484.15 CDO72657.1 - 0.071 13.4 0.1 2.9 8.2 0.0 3.4 3 1 0 3 3 3 0 tRNA synthetase B5 domain UL42 PF17638.2 CDO72658.1 - 2.5 8.1 12.2 18 5.3 0.1 2.5 2 0 0 2 2 2 0 HCMV UL42 WES_acyltransf PF03007.16 CDO72659.1 - 0.038 13.8 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain TEA PF01285.18 CDO72661.1 - 2.1e-23 82.2 0.0 7.6e-23 80.4 0.0 2.0 2 0 0 2 2 2 1 TEA/ATTS domain DUF4246 PF14033.6 CDO72662.1 - 6.8e-117 391.3 0.0 4e-115 385.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) MAGE PF01454.19 CDO72663.1 - 7.2e-51 172.9 0.0 1.1e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 MAGE family Adeno_terminal PF02459.15 CDO72663.1 - 0.11 10.8 1.4 0.15 10.4 1.4 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Pantoate_transf PF02548.15 CDO72664.1 - 1.4e-105 352.4 1.6 1.6e-105 352.1 1.6 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 CDO72664.1 - 3.9e-10 39.6 0.9 6e-10 39.0 0.1 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Lac_bphage_repr PF06543.12 CDO72667.1 - 0.15 12.1 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor NmrA PF05368.13 CDO72668.1 - 1.4e-31 109.8 0.0 2e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CDO72668.1 - 4.5e-14 52.8 0.2 1.1e-13 51.5 0.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CDO72668.1 - 0.0032 16.5 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CDO72668.1 - 0.0071 16.8 0.1 0.013 15.9 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 CDO72668.1 - 0.025 14.1 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ceramidase_alk PF04734.13 CDO72669.1 - 8.5e-207 687.8 0.0 5.4e-206 685.1 0.0 1.8 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 CDO72669.1 - 4.2e-46 156.9 0.1 7.6e-46 156.0 0.1 1.5 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal His_Phos_2 PF00328.22 CDO72670.1 - 0.00057 19.4 0.0 0.00098 18.6 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SRP_TPR_like PF17004.5 CDO72671.1 - 1.6e-15 57.1 0.8 2.2e-15 56.7 0.8 1.2 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 CDO72671.1 - 3.3e-08 33.8 1.0 9.3e-08 32.4 1.0 1.8 1 0 0 1 1 1 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 CDO72671.1 - 2.3e-07 30.9 4.9 0.00019 21.6 0.4 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CDO72671.1 - 1.1e-06 28.3 7.5 0.0056 16.7 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO72671.1 - 0.0011 19.4 18.2 0.064 13.8 0.3 3.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDO72671.1 - 0.0012 18.6 2.8 0.45 10.4 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDO72671.1 - 0.0016 18.5 5.3 0.02 15.1 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDO72671.1 - 0.0022 18.1 4.4 3.9 7.9 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDO72671.1 - 0.0044 17.6 3.7 0.092 13.4 0.2 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDO72671.1 - 0.0064 15.7 5.8 0.14 11.4 3.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDO72671.1 - 0.0072 17.1 13.2 0.37 11.7 0.5 4.1 3 2 1 4 4 3 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CDO72671.1 - 0.0075 16.7 1.9 0.48 10.9 0.5 2.3 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 CDO72671.1 - 0.012 15.7 0.1 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Lant_dehydr_C PF14028.6 CDO72671.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term TPR_12 PF13424.6 CDO72671.1 - 0.02 15.2 6.1 0.02 15.2 6.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDO72671.1 - 0.023 14.7 4.6 0.18 11.9 0.4 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDO72671.1 - 0.044 14.4 5.6 0.044 14.4 5.6 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF2989 PF11207.8 CDO72671.1 - 0.05 13.4 0.7 0.077 12.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) DUF2225 PF09986.9 CDO72671.1 - 0.15 11.8 0.2 0.21 11.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) RTA1 PF04479.13 CDO72672.1 - 0.00039 20.1 0.0 0.00047 19.8 0.0 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF4381 PF14316.6 CDO72672.1 - 0.0044 17.3 0.1 0.0065 16.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Rax2 PF12768.7 CDO72672.1 - 0.037 13.5 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF5305 PF17231.2 CDO72672.1 - 0.16 11.3 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 CDO72672.1 - 0.18 12.7 0.0 0.5 11.3 0.0 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DRIM PF07539.12 CDO72673.1 - 3.5e-178 593.8 6.6 3.5e-178 593.8 6.6 4.8 5 0 0 5 5 5 1 Down-regulated in metastasis Dynamin_M PF01031.20 CDO72673.1 - 1.7e-26 93.1 0.0 1e-24 87.3 0.0 3.4 2 1 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CDO72673.1 - 1.7e-11 44.4 0.0 1.7e-10 41.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family HEAT_EZ PF13513.6 CDO72673.1 - 0.0011 19.4 5.0 0.3 11.6 0.0 6.5 6 0 0 6 6 6 1 HEAT-like repeat KIND PF16474.5 CDO72673.1 - 0.0025 17.8 0.1 0.01 15.8 0.0 2.0 2 0 0 2 2 2 1 Kinase non-catalytic C-lobe domain CLASP_N PF12348.8 CDO72673.1 - 0.0087 15.7 4.8 4.1 6.9 0.0 5.1 4 1 0 4 4 4 1 CLASP N terminal HEAT PF02985.22 CDO72673.1 - 0.0093 16.1 3.3 99 3.6 0.0 6.5 5 0 0 5 5 5 0 HEAT repeat MMS19_N PF14500.6 CDO72673.1 - 0.014 15.0 5.0 0.084 12.4 0.4 3.8 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II GED PF02212.18 CDO72673.1 - 0.02 15.1 0.1 0.13 12.4 0.0 2.6 2 0 0 2 2 2 0 Dynamin GTPase effector domain Bcl-2 PF00452.19 CDO72673.1 - 0.03 15.0 0.6 9.7 7.0 0.0 4.8 3 0 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family Condensin2nSMC PF12422.8 CDO72673.1 - 0.031 14.5 6.4 30 4.7 0.0 6.4 6 1 0 6 6 6 0 Condensin II non structural maintenance of chromosomes subunit DUF4404 PF14357.6 CDO72673.1 - 0.23 12.1 2.7 15 6.3 0.7 4.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Sugar_tr PF00083.24 CDO72674.1 - 3.1e-121 405.4 24.9 3.5e-121 405.2 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO72674.1 - 4.6e-18 65.3 42.3 7.1e-14 51.5 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO72675.1 - 1.1e-121 406.9 17.5 1.2e-121 406.7 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO72675.1 - 5.5e-20 71.6 41.1 3.2e-17 62.5 12.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_30 PF13604.6 CDO72676.1 - 7.7e-18 64.9 0.0 2.1e-17 63.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDO72676.1 - 2.1e-14 54.0 0.0 7.1e-07 29.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 CDO72676.1 - 1.3e-13 51.0 0.0 3.2e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDO72676.1 - 3.8e-12 46.8 0.0 1.3e-11 45.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CDO72676.1 - 4.4e-05 23.9 0.0 9.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 CDO72676.1 - 0.00075 19.3 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 CDO72676.1 - 0.00075 19.4 0.1 0.35 10.8 0.0 2.4 2 0 0 2 2 2 2 NACHT domain PhoH PF02562.16 CDO72676.1 - 0.0018 17.8 0.0 0.0043 16.5 0.0 1.6 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 CDO72676.1 - 0.0023 18.2 0.0 0.015 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CDO72676.1 - 0.0068 16.8 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 CDO72676.1 - 0.0092 15.8 0.0 0.048 13.5 0.0 2.0 1 1 0 1 1 1 1 Helicase T2SSE PF00437.20 CDO72676.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 CDO72676.1 - 0.03 14.5 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDO72676.1 - 0.044 13.4 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 CDO72676.1 - 0.05 13.1 0.0 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ResIII PF04851.15 CDO72676.1 - 0.08 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit EphA2_TM PF14575.6 CDO72677.1 - 0.02 15.8 1.0 0.028 15.3 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cadherin_C_2 PF16492.5 CDO72677.1 - 0.054 14.2 0.3 0.34 11.7 0.0 2.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal TMEM154 PF15102.6 CDO72677.1 - 0.054 13.4 0.0 0.054 13.4 0.0 2.9 2 1 1 3 3 3 0 TMEM154 protein family Rax2 PF12768.7 CDO72677.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity LRRC37AB_C PF14914.6 CDO72677.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain MLANA PF14991.6 CDO72677.1 - 0.27 11.5 0.0 0.27 11.5 0.0 2.5 4 0 0 4 4 4 0 Protein melan-A Adeno_E3_CR2 PF02439.15 CDO72677.1 - 2.5 7.9 5.5 4.7 7.1 5.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pinin_SDK_memA PF04696.13 CDO72680.1 - 1.8e-12 47.4 22.6 1.8e-12 47.4 22.6 4.1 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region RNA_pol_Rpb1_3 PF04983.18 CDO72680.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 DUF1640 PF07798.11 CDO72680.1 - 7.2 6.6 17.3 1.1 9.3 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) CTK3 PF12243.8 CDO72681.1 - 4.3e-36 123.6 0.0 5.9e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 CDO72681.1 - 2.7e-23 81.9 3.4 5.9e-23 80.8 3.4 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTD_bind PF04818.13 CDO72681.1 - 0.08 13.8 0.0 0.26 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Flavin_Reduct PF01613.18 CDO72682.1 - 1.9e-19 70.3 0.1 2.7e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain RNA_pol_A_bac PF01000.26 CDO72683.1 - 1.1e-23 83.7 0.0 2.1e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CDO72683.1 - 2.6e-19 68.4 0.0 3.8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain AAA_12 PF13087.6 CDO72684.1 - 3.9e-26 91.9 0.1 1e-25 90.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDO72684.1 - 5.5e-19 68.6 0.0 6.5e-18 65.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CDO72684.1 - 1.3e-17 64.5 0.0 1.2e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CDO72684.1 - 4.2e-13 49.9 0.0 1.6e-12 47.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 CDO72684.1 - 8.1e-05 22.5 0.3 1.2 8.9 0.2 3.2 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 CDO72684.1 - 0.00018 21.1 0.0 0.025 14.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.6 CDO72684.1 - 0.00032 21.1 0.0 0.00079 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDO72684.1 - 0.00044 20.5 0.0 0.039 14.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CDO72684.1 - 0.0016 17.6 0.0 0.025 13.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 CDO72684.1 - 0.0026 18.2 0.0 0.0062 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CDO72684.1 - 0.0031 16.8 0.0 2 7.6 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 CDO72684.1 - 0.0042 16.9 0.1 0.01 15.7 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 CDO72684.1 - 0.0099 15.7 0.0 0.44 10.4 0.0 2.9 2 1 0 2 2 2 1 Helicase AAA_33 PF13671.6 CDO72684.1 - 0.021 15.0 0.1 0.09 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDO72684.1 - 0.027 14.4 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DEAD PF00270.29 CDO72684.1 - 0.049 13.4 0.1 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 CDO72684.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 CDO72684.1 - 0.094 12.6 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 CDO72684.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 CDO72684.1 - 0.12 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 CDO72684.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Peptidase_S28 PF05577.12 CDO72685.1 - 5.3e-45 154.0 2.3 1.9e-44 152.2 2.3 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 CDO72685.1 - 0.0018 17.8 0.4 0.0035 16.9 0.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CDO72685.1 - 0.12 11.7 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CFEM PF05730.11 CDO72686.1 - 2.2e-06 27.7 10.7 4.4e-06 26.7 10.7 1.5 1 0 0 1 1 1 1 CFEM domain Dus PF01207.17 CDO72687.1 - 5.6e-25 88.1 0.0 6.4e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) G-alpha PF00503.20 CDO72689.1 - 1.2e-114 383.2 1.0 1.3e-114 383.1 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDO72689.1 - 6.1e-14 51.8 0.2 3e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDO72689.1 - 0.00012 21.5 0.0 0.52 9.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CDO72689.1 - 0.018 15.2 0.0 0.42 10.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CDO72689.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1236 PF06823.12 CDO72692.1 - 0.069 13.0 0.7 0.17 11.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1236) RIFIN PF02009.16 CDO72692.1 - 1 9.2 6.0 1.2 9.0 6.0 1.2 1 0 0 1 1 1 0 Rifin Nitroreductase PF00881.24 CDO72693.1 - 1.9e-18 67.1 0.0 2.2e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family DUF2194 PF09960.9 CDO72693.1 - 0.18 10.1 0.0 0.2 10.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) TM1586_NiRdase PF14512.6 CDO72693.1 - 0.2 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative TM nitroreductase FSIP2 PF15783.5 CDO72694.1 - 7.1 4.4 9.2 8.7 4.1 9.2 1.0 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 6PGD PF00393.19 CDO72694.1 - 7.2 5.9 7.9 9.8 5.5 7.9 1.1 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain RIFIN PF02009.16 CDO72694.1 - 7.3 6.4 12.1 8.5 6.2 12.1 1.2 1 0 0 1 1 1 0 Rifin Miga PF10265.9 CDO72694.1 - 8.3 5.3 6.7 10 5.0 6.7 1.0 1 0 0 1 1 1 0 Mitoguardin MOR2-PAG1_mid PF14228.6 CDO72695.1 - 0.11 10.1 3.2 0.12 9.9 3.2 1.0 1 0 0 1 1 1 0 Cell morphogenesis central region Methyltransf_2 PF00891.18 CDO72696.1 - 7.7e-18 64.6 0.0 1.3e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain 4HBT PF03061.22 CDO72697.1 - 1.6e-10 41.2 0.0 2.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Pyr_redox_2 PF07992.14 CDO72702.1 - 3.1e-08 33.2 0.0 4.3e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO72702.1 - 4.2e-08 33.3 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 CDO72702.1 - 8.3e-07 27.8 0.2 0.00072 18.1 0.1 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Thi4 PF01946.17 CDO72702.1 - 1e-05 24.9 0.0 2.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 CDO72702.1 - 0.00015 21.8 0.1 0.052 13.5 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CDO72702.1 - 0.0053 16.1 0.3 3.3 6.9 0.3 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDO72702.1 - 0.031 13.4 0.2 0.05 12.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 CDO72702.1 - 0.07 12.7 0.6 0.21 11.1 0.6 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase RVT_1 PF00078.27 CDO72703.1 - 2.3e-20 73.1 0.0 8.3e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO72703.1 - 1.8e-09 37.9 0.0 3.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.6 CDO72703.1 - 7.8e-05 22.5 0.6 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDO72703.1 - 0.0006 19.4 1.4 0.0027 17.3 1.4 2.1 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 CDO72703.1 - 0.01 16.5 0.3 0.043 14.5 0.0 2.2 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase HNH_2 PF13391.6 CDO72705.1 - 8.9e-05 22.6 0.0 0.00025 21.1 0.0 1.8 1 1 0 1 1 1 1 HNH endonuclease EF_assoc_2 PF08356.12 CDO72705.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 EF hand associated Apt1 PF10351.9 CDO72706.1 - 8.1 5.2 7.7 7.5 5.3 7.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lipocalin_8 PF16585.5 CDO72707.1 - 0.1 13.1 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipocalin-like domain Methyltransf_2 PF00891.18 CDO72708.1 - 6.1e-19 68.1 0.0 2.5e-17 62.9 0.0 2.4 2 0 0 2 2 2 2 O-methyltransferase domain MTS PF05175.14 CDO72708.1 - 0.019 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Aminotran_5 PF00266.19 CDO72710.1 - 1.1e-29 103.6 0.0 2.3e-27 95.9 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Plavaka PF18759.1 CDO72712.1 - 8.2e-13 48.3 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Importin_rep PF18773.1 CDO72712.1 - 0.26 11.0 1.7 1.1 9.1 0.1 2.5 3 0 0 3 3 3 0 Importin 13 repeat Plavaka PF18759.1 CDO72713.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase BRD4_CDT PF17105.5 CDO72714.1 - 1.3 8.7 3.4 3.2 7.4 3.4 1.7 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 MFS_1 PF07690.16 CDO72715.1 - 5.3e-27 94.7 40.1 8.8e-27 93.9 39.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily HCV_NS4b PF01001.19 CDO72715.1 - 0.048 13.3 5.1 0.11 12.1 1.1 2.8 2 1 1 3 3 3 0 Hepatitis C virus non-structural protein NS4b MFS_1_like PF12832.7 CDO72715.1 - 0.19 10.6 18.5 0.26 10.1 7.5 2.3 1 1 1 2 2 2 0 MFS_1 like family Methyltransf_2 PF00891.18 CDO72716.1 - 3.4e-10 39.6 0.0 4.4e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain MTS PF05175.14 CDO72716.1 - 0.033 13.7 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Importin_rep_4 PF18808.1 CDO72717.1 - 9.5e-20 70.7 0.1 1.8e-18 66.6 0.0 2.4 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 CDO72717.1 - 1.9e-07 31.5 6.6 0.058 13.9 0.1 6.1 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 CDO72717.1 - 0.0031 17.7 9.6 4.5 7.8 0.0 6.7 8 0 0 8 8 8 1 HEAT repeat MMS19_C PF12460.8 CDO72717.1 - 0.058 12.5 0.5 0.37 9.9 0.0 2.4 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Mito_fiss_reg PF05308.11 CDO72717.1 - 1.1 9.3 4.2 1.9 8.5 4.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Plavaka PF18759.1 CDO72719.1 - 2.5e-123 411.5 0.0 3.4e-123 411.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 CDO72719.1 - 0.79 10.3 4.6 0.2 12.2 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type COX4 PF02936.14 CDO72720.1 - 0.52 10.3 3.2 1.6 8.8 0.2 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV GHMP_kinases_N PF00288.26 CDO72723.1 - 1.4e-10 41.2 0.0 2.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CDO72723.1 - 0.0064 16.8 0.1 0.047 14.1 0.1 2.3 2 1 0 2 2 2 1 GHMP kinases C terminal AAA_6 PF12774.7 CDO72724.1 - 3.7e-128 427.1 0.0 3.1e-127 424.1 0.0 2.7 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CDO72724.1 - 8.1e-117 390.7 7.5 8.1e-117 390.7 7.5 3.4 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CDO72724.1 - 1.2e-74 250.1 0.4 1.2e-74 250.1 0.4 5.0 7 1 1 8 8 6 1 ATP-binding dynein motor region AAA_8 PF12780.7 CDO72724.1 - 1e-68 231.5 0.0 5.6e-68 229.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CDO72724.1 - 9.5e-51 172.8 0.0 3.2e-50 171.1 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CDO72724.1 - 4.3e-43 146.9 0.0 4.7e-37 127.2 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 CDO72724.1 - 7.7e-42 143.5 7.1 1.3e-41 142.8 7.1 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CDO72724.1 - 6.6e-37 126.9 0.0 1.4e-36 125.8 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CDO72724.1 - 3.3e-30 104.6 0.0 1e-28 99.8 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CDO72724.1 - 3.1e-27 95.3 0.0 2e-10 40.8 0.0 6.6 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CDO72724.1 - 1.6e-16 60.6 0.0 1e-15 58.0 0.0 2.6 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CDO72724.1 - 8.7e-13 48.8 0.2 0.0021 18.5 0.0 5.0 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDO72724.1 - 1.8e-12 47.7 0.0 0.006 16.9 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 CDO72724.1 - 6.8e-11 42.5 1.9 0.14 12.3 0.0 5.9 5 1 1 6 6 6 3 AAA domain AAA_16 PF13191.6 CDO72724.1 - 1.5e-08 35.2 0.0 0.61 10.5 0.0 6.3 5 0 0 5 5 5 1 AAA ATPase domain AAA_18 PF13238.6 CDO72724.1 - 4.5e-08 33.7 1.3 0.068 13.7 0.0 6.0 5 0 0 5 5 4 2 AAA domain FtsK_SpoIIIE PF01580.18 CDO72724.1 - 5.7e-07 29.1 0.0 0.26 10.6 0.0 4.6 4 0 0 4 4 4 2 FtsK/SpoIIIE family T2SSE PF00437.20 CDO72724.1 - 9.3e-06 24.9 0.0 0.018 14.1 0.0 3.7 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 CDO72724.1 - 1.7e-05 24.3 2.0 0.65 9.3 0.0 3.8 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 CDO72724.1 - 4e-05 23.3 0.1 0.74 9.6 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 CDO72724.1 - 0.00019 21.6 2.7 0.00051 20.2 0.0 3.0 3 0 0 3 3 2 1 AAA+ lid domain AAA_19 PF13245.6 CDO72724.1 - 0.00035 20.9 0.3 0.31 11.4 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 CDO72724.1 - 0.00048 19.9 0.2 26 4.5 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.6 CDO72724.1 - 0.00069 19.7 0.0 2.1 8.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CDO72724.1 - 0.00073 19.3 0.6 0.73 9.5 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CDO72724.1 - 0.0013 19.1 0.0 5.5 7.4 0.0 4.7 5 0 0 5 5 4 0 RNA helicase Rad17 PF03215.15 CDO72724.1 - 0.0015 18.5 0.1 24 4.8 0.0 4.9 5 0 0 5 5 5 0 Rad17 P-loop domain AAA_21 PF13304.6 CDO72724.1 - 0.009 15.9 0.0 4.6 7.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CDO72724.1 - 0.009 16.5 5.1 12 6.4 0.0 4.8 5 0 0 5 5 3 0 ABC transporter UPF0489 PF12640.7 CDO72724.1 - 0.01 16.0 0.9 0.03 14.6 0.9 1.8 1 0 0 1 1 1 0 UPF0489 domain AAA_24 PF13479.6 CDO72724.1 - 0.013 15.2 0.9 22 4.7 0.0 4.2 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 CDO72724.1 - 0.022 14.3 0.0 0.63 9.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CDO72724.1 - 0.052 13.5 0.7 39 4.1 0.1 4.7 4 0 0 4 4 3 0 NACHT domain Lipocalin_8 PF16585.5 CDO72724.1 - 0.11 12.9 0.1 0.95 9.9 0.0 2.3 2 0 0 2 2 2 0 Lipocalin-like domain RuvB_N PF05496.12 CDO72724.1 - 0.13 12.0 0.0 3.2 7.5 0.0 2.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain UPF0242 PF06785.11 CDO72724.1 - 0.5 10.4 23.1 0.73 9.9 2.6 3.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_11 PF13086.6 CDO72724.1 - 3.1 7.5 16.4 1.3 8.8 0.0 4.4 5 0 0 5 5 4 0 AAA domain LSM PF01423.22 CDO72725.1 - 2e-14 53.0 0.3 2.8e-14 52.5 0.3 1.3 1 1 0 1 1 1 1 LSM domain Hfq PF17209.3 CDO72725.1 - 0.0022 17.6 0.2 0.0038 16.8 0.2 1.5 1 0 0 1 1 1 1 Hfq protein Romo1 PF10247.9 CDO72726.1 - 2.4e-23 82.3 9.2 3.4e-23 81.8 9.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 TPR_1 PF00515.28 CDO72727.1 - 0.00047 19.8 0.6 0.11 12.4 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat 2_5_RNA_ligase2 PF13563.6 CDO72727.1 - 0.022 14.6 1.1 0.042 13.7 0.2 1.9 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily TPR_2 PF07719.17 CDO72727.1 - 0.34 11.1 4.0 2.7 8.3 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CDO72727.1 - 1.3 8.7 3.2 4.5 7.0 0.1 2.7 3 0 0 3 3 3 0 TPR repeat Ammonium_transp PF00909.21 CDO72728.1 - 2.9e-66 223.8 5.1 6.3e-47 160.1 2.7 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family DUF3512 PF12024.8 CDO72729.1 - 0.046 13.2 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) L51_S25_CI-B8 PF05047.16 CDO72730.1 - 1.2e-12 47.5 0.4 1.9e-12 46.9 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PBP1_TM PF14812.6 CDO72731.1 - 0.029 14.7 0.1 0.029 14.7 0.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med3 PF11593.8 CDO72731.1 - 0.79 8.8 3.6 1.4 8.0 3.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Aldo_ket_red PF00248.21 CDO72733.1 - 1.1e-39 136.4 0.0 1.3e-37 129.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family IGPS PF00218.21 CDO72734.1 - 7.8e-90 300.5 0.0 8.8e-90 300.3 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.19 CDO72734.1 - 0.0012 18.6 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.18 CDO72734.1 - 0.026 13.6 0.4 0.039 13.0 0.4 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 CDO72734.1 - 0.033 13.6 0.1 0.17 11.3 0.1 2.0 2 1 1 3 3 3 0 Histidine biosynthesis protein F-box-like PF12937.7 CDO72735.1 - 1.7e-05 24.6 0.2 4.6e-05 23.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO72735.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain G10 PF01125.17 CDO72735.1 - 0.022 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 G10 protein DLH PF01738.18 CDO72736.1 - 1.8e-14 53.8 0.0 2.1e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 CDO72737.1 - 4.2e-12 46.1 0.0 5e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Pkinase PF00069.25 CDO72738.1 - 1.7e-48 165.3 0.0 3.8e-48 164.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain RhoGAP PF00620.27 CDO72738.1 - 3.4e-40 137.4 0.1 7e-40 136.3 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain Pkinase_Tyr PF07714.17 CDO72738.1 - 4.2e-38 131.1 0.0 8.8e-21 74.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO72738.1 - 0.00023 20.1 0.0 0.00059 18.7 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase DUF1708 PF08101.11 CDO72738.1 - 0.031 13.4 0.0 0.098 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Kinase-like PF14531.6 CDO72738.1 - 0.091 12.1 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Histone PF00125.24 CDO72738.1 - 0.1 13.0 0.2 0.46 10.8 0.2 2.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 FAM92 PF06730.11 CDO72738.1 - 0.13 11.6 4.8 0.14 11.5 1.2 2.2 2 0 0 2 2 2 0 FAM92 protein RRM_1 PF00076.22 CDO72739.1 - 6.7e-14 51.5 0.1 9.6e-14 51.0 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 CDO72739.1 - 9e-09 35.0 2.7 1.5e-08 34.3 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDO72739.1 - 3.2e-05 23.8 0.0 6.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CDO72739.1 - 0.0011 18.6 1.9 0.0041 16.8 1.9 2.0 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 CDO72739.1 - 0.21 11.3 0.2 0.34 10.7 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle Rieske PF00355.26 CDO72740.1 - 3.2e-11 43.0 0.0 5.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CDO72740.1 - 2.3e-10 40.8 0.6 2.3e-10 40.8 0.6 2.1 2 1 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region SUKH-4 PF14435.6 CDO72740.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 SUKH-4 immunity protein GDPD PF03009.17 CDO72741.1 - 2.2e-35 122.6 0.0 3.4e-35 122.0 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 CDO72741.1 - 0.00015 22.1 0.6 0.0042 17.5 0.5 2.5 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CHCH PF06747.13 CDO72742.1 - 5.7e-07 29.5 1.9 9.4e-07 28.8 1.9 1.4 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 CDO72742.1 - 0.066 13.0 1.2 0.11 12.2 1.2 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 CDO72742.1 - 0.16 12.3 2.6 0.42 10.9 2.5 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NPL4 PF05021.15 CDO72743.1 - 2.8e-103 345.5 0.0 3.5e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CDO72743.1 - 9.1e-67 223.7 0.0 1.8e-66 222.8 0.0 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 CDO72743.1 - 0.00018 22.0 0.0 0.00034 21.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 DNA_pol_A_exo1 PF01612.20 CDO72744.1 - 3e-18 66.1 0.1 3.7e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 3'-5' exonuclease VSP PF03302.13 CDO72745.1 - 0.0096 14.8 0.1 0.015 14.2 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein SprB PF13573.6 CDO72745.1 - 0.033 14.0 2.0 0.034 13.9 0.0 2.1 2 0 0 2 2 2 0 SprB repeat Las1 PF04031.13 CDO72746.1 - 3.4e-46 157.2 0.6 8.8e-46 155.8 0.2 1.9 3 0 0 3 3 3 1 Las1-like p450 PF00067.22 CDO72747.1 - 4e-49 167.6 0.0 1.1e-48 166.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Integrase_H2C2 PF17921.1 CDO72748.1 - 3.8e-18 65.3 2.1 7.3e-18 64.4 2.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO72748.1 - 3.1e-09 37.1 0.1 1e-08 35.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CDO72748.1 - 0.073 13.3 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 DDE domain ATP_transf PF09830.9 CDO72749.1 - 4e-21 74.9 0.1 6.6e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase SKG6 PF08693.10 CDO72751.1 - 0.0004 19.7 3.8 0.00097 18.5 3.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 CDO72751.1 - 0.0095 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Amnionless Rax2 PF12768.7 CDO72751.1 - 0.1 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.6 CDO72751.1 - 0.12 13.2 0.0 0.22 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GT87 PF09594.10 CDO72751.1 - 0.21 11.3 1.6 0.23 11.2 0.4 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 87 HicA_toxin PF07927.12 CDO72752.1 - 3.4e-08 33.4 0.0 9.1e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, RabGAP-TBC PF00566.18 CDO72753.1 - 5.1e-53 179.9 0.0 7.3e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 CDO72753.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Interleukin 34 NUP50 PF08911.11 CDO72754.1 - 1.5e-17 64.0 0.6 1.5e-17 64.0 0.6 6.7 5 3 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 CDO72754.1 - 2e-12 47.4 0.4 3.8e-12 46.5 0.4 1.4 1 0 0 1 1 1 1 RanBP1 domain TIG PF01833.24 CDO72755.1 - 1.4e-11 44.3 0.5 4.6e-11 42.7 0.5 2.0 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.6 CDO72755.1 - 2.7e-08 33.4 0.1 0.0019 18.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CDO72755.1 - 3.7e-08 33.8 0.0 6.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDO72755.1 - 3.4e-06 27.2 1.3 0.0014 18.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDO72755.1 - 3.9e-06 27.3 0.2 4.5e-05 23.9 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CDO72755.1 - 6.9e-05 23.1 0.9 0.43 11.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat TIG_plexin PF17960.1 CDO72755.1 - 0.0031 17.5 0.3 0.1 12.6 0.0 2.8 2 1 0 2 2 2 1 TIG domain F-box-like PF12937.7 CDO72756.1 - 0.023 14.6 0.2 0.15 12.0 0.0 2.5 2 0 0 2 2 2 0 F-box-like UDPGT PF00201.18 CDO72757.1 - 1.2e-21 77.1 0.1 1.7e-21 76.6 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO72757.1 - 0.0024 17.9 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Fe_hyd_lg_C PF02906.14 CDO72759.1 - 4.2e-51 173.9 0.0 1e-50 172.7 0.0 1.6 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain SNARE PF05739.19 CDO72760.1 - 1e-14 54.2 0.7 2.5e-14 53.0 0.1 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CDO72760.1 - 4.7e-05 23.2 3.9 4.7e-05 23.2 3.9 2.5 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.6 CDO72760.1 - 0.00027 21.3 0.6 0.069 13.5 0.0 2.6 3 0 0 3 3 3 2 Syntaxin-like protein BLOC1_2 PF10046.9 CDO72760.1 - 0.051 13.9 4.7 0.066 13.5 2.1 2.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SKA1 PF07160.12 CDO72760.1 - 0.8 9.5 4.3 0.61 9.9 0.4 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 MS_channel PF00924.18 CDO72761.1 - 6e-24 84.7 0.2 1.1e-23 83.9 0.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 CDO72761.1 - 0.0081 15.6 0.6 0.018 14.6 0.6 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDO72761.1 - 0.0088 15.9 0.1 0.028 14.4 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CDO72761.1 - 0.13 11.8 0.5 0.33 10.5 0.2 1.9 2 0 0 2 2 2 0 EF hand RNA_pol_A_bac PF01000.26 CDO72762.1 - 5e-17 62.3 0.0 8.8e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CDO72762.1 - 1.8e-08 33.7 0.0 7.5e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pro-kuma_activ PF09286.11 CDO72763.1 - 3e-37 128.1 0.0 3.1e-36 124.8 0.0 2.3 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO72763.1 - 0.00016 21.0 0.2 0.00025 20.4 0.2 1.2 1 0 0 1 1 1 1 Subtilase family UDPGT PF00201.18 CDO72764.1 - 1.9e-21 76.4 0.0 3.3e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO72764.1 - 0.007 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain LETM1 PF07766.13 CDO72765.1 - 4.1e-30 105.0 0.1 4e-14 52.6 0.0 2.1 1 1 1 2 2 2 2 LETM1-like protein TPR_2 PF07719.17 CDO72766.1 - 4.4e-36 120.1 59.0 1.4e-05 24.9 0.5 19.2 19 0 0 19 19 19 8 Tetratricopeptide repeat TPR_1 PF00515.28 CDO72766.1 - 9.5e-36 120.2 22.4 1.2e-05 24.8 0.1 15.1 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_16 PF13432.6 CDO72766.1 - 1.1e-26 93.2 84.0 2.1e-08 34.7 3.8 14.7 10 4 5 16 16 16 11 Tetratricopeptide repeat TPR_14 PF13428.6 CDO72766.1 - 2.8e-26 90.0 86.2 3.9e-05 24.1 1.1 20.4 15 6 7 22 22 20 9 Tetratricopeptide repeat TPR_8 PF13181.6 CDO72766.1 - 4.1e-26 89.0 32.8 9.4e-05 22.3 0.1 16.1 17 0 0 17 17 17 4 Tetratricopeptide repeat TPR_11 PF13414.6 CDO72766.1 - 2.2e-22 78.4 27.5 0.0046 16.6 1.5 15.9 14 2 3 17 17 17 4 TPR repeat TPR_12 PF13424.6 CDO72766.1 - 6.7e-19 68.0 57.4 0.00027 21.2 0.7 13.2 11 3 2 14 14 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 CDO72766.1 - 7.2e-18 64.9 51.6 5.8e-05 23.5 0.0 13.7 10 4 5 15 15 15 5 Tetratricopeptide repeat TPR_17 PF13431.6 CDO72766.1 - 1.1e-13 50.5 27.6 0.043 14.2 0.1 15.1 16 1 1 17 17 17 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO72766.1 - 5.4e-13 48.0 29.6 0.6 10.3 0.2 13.7 15 0 0 15 15 15 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDO72766.1 - 7.2e-10 38.9 53.0 2.6e-05 24.3 0.2 11.0 10 3 3 13 13 13 4 Tetratricopeptide repeat TPR_6 PF13174.6 CDO72766.1 - 1.3e-09 38.0 39.9 0.11 13.2 0.3 14.8 17 1 1 18 18 15 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO72766.1 - 2.7e-09 37.1 13.8 0.0075 16.5 0.0 8.5 7 3 2 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 CDO72766.1 - 4.1e-05 23.4 6.4 1.5 8.5 0.1 6.0 6 1 0 6 6 6 1 26S proteasome subunit RPN7 TPR_22 PF18833.1 CDO72766.1 - 0.0098 16.0 0.1 0.04 14.1 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat PhnG PF06754.12 CDO72766.1 - 0.04 13.9 1.5 0.29 11.1 1.3 2.5 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG NARP1 PF12569.8 CDO72766.1 - 0.082 11.8 3.6 7.2 5.4 0.0 3.6 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 TOM20_plant PF06552.12 CDO72766.1 - 0.25 11.1 2.6 4.2 7.1 0.0 3.9 4 1 0 5 5 4 0 Plant specific mitochondrial import receptor subunit TOM20 FAT PF02259.23 CDO72766.1 - 1.1 8.4 8.4 17 4.5 0.0 5.0 6 0 0 6 6 6 0 FAT domain TPR_20 PF14561.6 CDO72766.1 - 1.8 9.0 22.8 2.8 8.3 0.0 8.1 9 4 3 12 12 10 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDO72766.1 - 2 8.4 36.0 0.3 11.0 0.3 9.5 11 0 0 11 11 9 0 Tetratricopeptide repeat Chitin_synth_2 PF03142.15 CDO72767.1 - 2.6e-252 838.1 0.1 3.3e-252 837.8 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CDO72767.1 - 7.5e-15 55.4 0.1 3.1e-13 50.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CDO72767.1 - 1.3e-12 48.1 7.9 1.3e-12 48.1 7.9 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 CDO72767.1 - 0.00077 19.0 0.1 0.048 13.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CDO72767.1 - 0.048 13.5 0.0 0.57 10.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 DSPc PF00782.20 CDO72768.1 - 4.9e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CDO72768.1 - 0.00026 21.2 0.0 0.00056 20.1 0.0 1.5 2 0 0 2 2 2 1 Inositol hexakisphosphate CDKN3 PF05706.12 CDO72768.1 - 0.0049 16.5 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 CDO72768.1 - 0.019 14.5 0.4 0.083 12.4 0.4 1.9 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CDO72768.1 - 0.057 13.4 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DOCK_N PF16172.5 CDO72772.1 - 1.8e-99 333.2 0.0 5.6e-98 328.3 0.0 2.4 1 1 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 CDO72772.1 - 2.1e-76 257.7 0.0 6.4e-76 256.1 0.0 1.7 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 CDO72772.1 - 2e-58 197.4 0.0 3.5e-56 190.1 0.0 2.7 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins M_domain PF12938.7 CDO72773.1 - 0.012 15.4 0.2 0.028 14.2 0.2 1.6 1 0 0 1 1 1 0 M domain of GW182 DUF4763 PF15960.5 CDO72773.1 - 0.055 12.8 5.4 0.098 12.0 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) SlyX PF04102.12 CDO72773.1 - 0.081 13.5 5.7 0.9 10.2 0.7 2.9 2 0 0 2 2 2 0 SlyX V_ATPase_I PF01496.19 CDO72773.1 - 0.4 8.6 1.1 0.58 8.0 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SKA2 PF16740.5 CDO72773.1 - 0.56 10.0 5.7 2.2 8.1 0.1 2.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 FapA PF03961.13 CDO72773.1 - 0.9 8.1 3.0 1.6 7.3 3.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlxA PF14282.6 CDO72773.1 - 0.95 9.5 7.0 2 8.5 7.0 1.5 1 0 0 1 1 1 0 FlxA-like protein OmpH PF03938.14 CDO72773.1 - 3.6 7.9 6.5 7.9 6.8 6.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 CDO72773.1 - 7.1 6.5 8.0 0.98 9.2 3.3 1.9 2 0 0 2 2 2 0 Septum formation initiator DHDPS PF00701.22 CDO72774.1 - 3.5e-27 94.9 0.0 1.3e-26 93.0 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family DSPc PF00782.20 CDO72775.1 - 6.5e-30 103.7 0.0 9.4e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Form_Nir_trans PF01226.17 CDO72776.1 - 8.5e-43 146.4 9.7 8.5e-43 146.4 9.7 1.6 2 0 0 2 2 2 1 Formate/nitrite transporter HutP PF09021.11 CDO72776.1 - 0.074 13.4 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 HutP TM_helix PF05552.12 CDO72776.1 - 0.2 11.6 1.4 0.43 10.6 1.4 1.5 1 0 0 1 1 1 0 Conserved TM helix CPBP PF02517.16 CDO72776.1 - 0.69 10.3 3.2 1.6 9.1 3.2 1.6 1 0 0 1 1 1 0 CPBP intramembrane metalloprotease MyTH4 PF00784.17 CDO72777.1 - 1.3e-30 106.1 0.0 3e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.27 CDO72777.1 - 4.2e-27 94.8 0.0 7e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain UDPGT PF00201.18 CDO72778.1 - 3.7e-16 59.0 0.1 5e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase G-alpha PF00503.20 CDO72779.1 - 2.2e-103 346.1 0.0 2.6e-103 345.9 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDO72779.1 - 5.5e-13 48.7 0.1 3e-09 36.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CDO72779.1 - 0.0031 17.7 0.0 3.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDO72779.1 - 0.005 16.3 0.0 0.0086 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 CDO72779.1 - 0.038 13.4 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 CDO72779.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CDO72779.1 - 0.15 11.8 0.0 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 CDO72779.1 - 0.21 11.1 0.0 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1932 PF09130.11 CDO72781.1 - 1.6e-16 60.1 0.1 7.6e-16 57.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 CDO72781.1 - 1.2e-07 32.1 0.0 2.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CDO72781.1 - 7.4e-06 25.6 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 CDO72781.1 - 0.011 16.3 0.0 0.026 15.1 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CDO72781.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CDO72781.1 - 0.024 14.3 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 CDO72781.1 - 0.051 13.5 0.7 0.051 13.5 0.7 1.7 2 0 0 2 2 2 0 Rossmann-like domain ComA PF02679.15 CDO72782.1 - 1.7e-70 237.2 0.0 3.3e-70 236.3 0.0 1.4 1 1 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) PEP_mutase PF13714.6 CDO72782.1 - 0.025 14.0 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Pox_A21 PF05323.12 CDO72782.1 - 0.2 12.2 0.0 0.34 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A21 Protein GST_N PF02798.20 CDO72783.1 - 7.9e-20 71.0 0.2 2.1e-19 69.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDO72783.1 - 8.9e-16 57.9 0.0 1.6e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDO72783.1 - 1.2e-12 48.1 0.0 2.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO72783.1 - 2.4e-12 46.9 0.0 5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDO72783.1 - 2.4e-11 43.7 0.1 4.7e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO72783.1 - 8.6e-07 28.9 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO72784.1 - 6.2e-19 68.1 0.1 1.7e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CDO72784.1 - 6.3e-13 48.9 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO72784.1 - 1.4e-12 47.7 0.0 2.8e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDO72784.1 - 8.3e-11 42.0 0.0 1.6e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO72784.1 - 7.2e-08 32.5 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO72784.1 - 8.6e-06 25.7 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CDO72784.1 - 0.038 13.8 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO72785.1 - 1.2e-19 70.4 0.1 3e-19 69.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDO72785.1 - 3.7e-15 55.9 0.0 6e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDO72785.1 - 4.5e-14 52.6 0.0 9.8e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO72785.1 - 2.6e-13 50.1 0.0 6.3e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDO72785.1 - 3e-12 46.6 0.0 5.5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO72785.1 - 1.8e-06 27.9 0.0 3.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CDO72785.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Plant_NMP1 PF06694.11 CDO72785.1 - 0.11 11.6 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Glyco_hydro_79C PF16862.5 CDO72787.1 - 8.1e-18 65.2 0.5 1e-17 64.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain zf-C2H2 PF00096.26 CDO72788.1 - 8.8e-08 32.2 12.6 0.00048 20.4 2.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO72788.1 - 6.1e-06 26.6 13.0 0.00047 20.8 1.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CDO72788.1 - 1.4e-05 25.3 17.7 2.3e-05 24.6 5.2 3.1 3 1 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 CDO72788.1 - 0.012 16.0 3.5 0.24 11.9 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CDO72788.1 - 0.021 14.8 13.7 0.11 12.6 3.4 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDO72788.1 - 0.029 14.1 5.3 0.25 11.1 0.3 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 CDO72788.1 - 0.056 13.3 0.6 0.17 11.7 0.8 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) XPA_N PF01286.18 CDO72788.1 - 0.074 13.1 2.8 0.074 13.1 2.8 1.5 2 0 0 2 2 2 0 XPA protein N-terminal zf-MYST PF17772.1 CDO72788.1 - 3.6 7.2 5.3 1.3 8.6 1.9 1.8 1 1 1 2 2 2 0 MYST family zinc finger domain Fungal_trans PF04082.18 CDO72789.1 - 6e-20 71.4 0.3 1.4e-19 70.2 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pro-kuma_activ PF09286.11 CDO72790.1 - 1.2e-35 122.9 0.1 2.1e-35 122.1 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO72790.1 - 9.1e-06 25.1 1.0 1.8e-05 24.1 0.7 1.6 1 1 1 2 2 2 1 Subtilase family O-FucT PF10250.9 CDO72791.1 - 2.8e-10 40.4 0.0 3.8e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Cellulase PF00150.18 CDO72792.1 - 3e-07 30.2 0.0 4.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF563 PF04577.14 CDO72793.1 - 1.1e-18 68.1 0.2 6.1e-17 62.4 0.0 2.9 2 1 0 3 3 3 1 Protein of unknown function (DUF563) MIP PF00230.20 CDO72794.1 - 3.4e-25 89.1 7.2 4.7e-25 88.6 7.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 CDO72795.1 - 4.1e-26 92.1 2.8 5.4e-26 91.7 2.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ferrochelatase PF00762.19 CDO72797.1 - 3.8e-103 344.9 0.0 4.3e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 CDO72797.1 - 0.00084 19.6 0.0 9.7 6.6 0.0 3.2 3 0 0 3 3 3 3 CbiX UNC-79 PF14776.6 CDO72797.1 - 0.29 9.8 0.0 0.39 9.4 0.0 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Q_salvage PF10343.9 CDO72798.1 - 1.1e-11 44.9 0.0 1.2e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family NAD_kinase PF01513.21 CDO72799.1 - 1.7e-72 244.1 0.0 4.6e-72 242.7 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase HMG_box PF00505.19 CDO72802.1 - 4.9e-13 49.3 3.3 4.9e-13 49.3 3.3 2.3 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO72802.1 - 5.7e-05 23.6 1.3 5.7e-05 23.6 1.3 2.3 1 1 1 2 2 2 1 HMG-box domain SLY PF12485.8 CDO72802.1 - 0.37 11.5 6.6 0.68 10.6 6.6 1.3 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein PHC2_SAM_assoc PF16616.5 CDO72802.1 - 3.2 8.6 11.3 8.4 7.2 11.3 1.7 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Rrn6 PF10214.9 CDO72802.1 - 4.4 5.7 10.3 6 5.2 10.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor HMG_box PF00505.19 CDO72803.1 - 2.2e-10 40.8 0.7 3.5e-10 40.2 0.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO72803.1 - 0.0012 19.3 0.3 0.0023 18.5 0.2 1.5 1 1 0 1 1 1 1 HMG-box domain Rrn6 PF10214.9 CDO72803.1 - 0.011 14.3 7.4 0.015 13.8 7.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BASP1 PF05466.12 CDO72803.1 - 0.88 9.5 8.7 1.6 8.7 8.7 1.4 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DUF829 PF05705.14 CDO72804.1 - 8.6e-45 153.5 0.0 9.8e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) ABA_GPCR PF12430.8 CDO72804.1 - 0.0071 16.1 0.3 0.01 15.6 0.3 1.2 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor Gsf2 PF11055.8 CDO72804.1 - 0.081 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Glucose signalling factor 2 TPR_19 PF14559.6 CDO72805.1 - 0.028 14.9 0.0 0.24 11.9 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat MCM PF00493.23 CDO72806.1 - 9.8e-101 335.5 0.0 1.5e-100 335.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM2_N PF12619.8 CDO72806.1 - 4.5e-32 111.4 35.1 4.5e-32 111.4 35.1 2.6 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 CDO72806.1 - 1.3e-24 86.4 0.6 4.9e-24 84.6 0.3 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_OB PF17207.3 CDO72806.1 - 6.3e-23 81.0 0.1 1.1e-15 57.6 0.0 2.4 1 1 1 2 2 2 2 MCM OB domain MCM_N PF14551.6 CDO72806.1 - 6.7e-12 45.9 0.0 2.4e-11 44.1 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CDO72806.1 - 1.2e-07 31.3 0.0 3.5e-06 26.6 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDO72806.1 - 3.3e-06 27.2 0.1 1.1e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CDO72806.1 - 0.00036 20.4 0.1 0.014 15.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDO72806.1 - 0.0021 17.8 0.1 0.017 14.8 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 CDO72806.1 - 0.11 13.0 0.1 1.3 9.4 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HMG_box PF00505.19 CDO72807.1 - 3.3e-14 53.0 0.4 3.3e-14 53.0 0.4 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO72807.1 - 2.9e-05 24.6 0.3 2.9e-05 24.6 0.3 1.9 2 0 0 2 2 2 1 HMG-box domain ABC_membrane PF00664.23 CDO72808.1 - 1.6e-35 123.1 9.0 2.5e-35 122.5 9.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDO72808.1 - 1.6e-33 116.1 0.0 3.2e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDO72808.1 - 3.8e-05 23.2 0.1 0.00064 19.2 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CDO72808.1 - 0.0062 16.3 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 CDO72808.1 - 0.0064 16.9 1.4 0.014 15.8 0.3 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CDO72808.1 - 0.0068 16.1 0.1 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CDO72808.1 - 0.011 16.0 0.0 0.077 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDO72808.1 - 0.015 15.2 0.1 0.038 13.9 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_21 PF13304.6 CDO72808.1 - 0.019 14.8 0.1 0.083 12.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 CDO72808.1 - 0.068 12.5 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 CDO72808.1 - 0.077 13.4 0.1 0.98 9.9 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 CDO72808.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF4713 PF15831.5 CDO72808.1 - 2.1 8.9 8.2 0.084 13.3 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) RRM_1 PF00076.22 CDO72809.1 - 3.5e-10 39.5 0.0 4.7e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Plavaka PF18759.1 CDO72812.1 - 5.4e-38 131.0 0.0 8.7e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Gelsolin PF00626.22 CDO72812.1 - 5e-15 55.2 0.0 6.8e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 Gelsolin repeat RVT_2 PF07727.14 CDO72813.1 - 5.9e-07 29.4 0.0 8.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MscS_TM PF12794.7 CDO72814.1 - 0.0079 15.1 0.5 0.015 14.2 0.5 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 UPF0242 PF06785.11 CDO72814.1 - 2.8 8.0 9.3 5.1 7.2 9.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4611 PF15387.6 CDO72814.1 - 9.8 6.5 15.0 5.2 7.3 7.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RVT_1 PF00078.27 CDO72815.1 - 4.4e-27 95.1 0.0 5.9e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 CDO72816.1 - 1.2e-08 35.4 7.7 0.072 14.0 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat SRA1 PF07304.11 CDO72816.1 - 7.5e-08 32.3 0.0 7.5e-08 32.3 0.0 3.1 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 CDO72816.1 - 0.0084 16.2 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Prp18 domain Sec16 PF12932.7 CDO72816.1 - 0.084 13.5 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Lipase_3 PF01764.25 CDO72817.1 - 1.7e-08 34.4 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDO72817.1 - 4.3 7.9 9.4 0.21 12.1 2.6 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family IstB_IS21_ATP PF08483.11 CDO72818.1 - 0.08 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal Tad PF13400.6 CDO72818.1 - 0.12 12.7 8.6 1.8 8.9 0.4 3.2 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like VATC PF18716.1 CDO72819.1 - 0.35 10.7 2.9 0.55 10.1 2.9 1.3 1 0 0 1 1 1 0 Vms1-associating treble clef domain Aldo_ket_red PF00248.21 CDO72820.1 - 6.2e-41 140.5 0.0 1.5e-40 139.2 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Transp_cyt_pur PF02133.15 CDO72821.1 - 1.5e-63 215.1 36.6 7.1e-46 156.9 16.3 3.0 1 1 2 3 3 3 3 Permease for cytosine/purines, uracil, thiamine, allantoin GRA6 PF05084.13 CDO72821.1 - 2.6 7.9 4.1 5.5 6.9 0.2 2.2 2 0 0 2 2 2 0 Granule antigen protein (GRA6) ICMT PF04140.14 CDO72822.1 - 9e-15 54.9 1.0 9e-15 54.9 1.0 2.7 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO72822.1 - 1.9e-11 44.3 0.4 3e-10 40.4 0.5 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO72822.1 - 1.4e-08 34.0 0.2 1.9e-08 33.5 0.2 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family HTH_28 PF13518.6 CDO72822.1 - 0.019 15.1 2.3 0.61 10.3 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain DUF1295 PF06966.12 CDO72822.1 - 0.023 14.2 0.4 0.035 13.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) GMC_oxred_C PF05199.13 CDO72823.1 - 1.5e-37 129.3 0.2 2.4e-37 128.6 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CDO72823.1 - 9.9e-34 117.1 0.0 1.3e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GST_N_3 PF13417.6 CDO72824.1 - 1.4e-10 41.5 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO72824.1 - 9.4e-10 38.7 0.0 1.8e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO72824.1 - 9.4e-09 35.5 0.0 2.5e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO72824.1 - 0.0054 16.7 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO72824.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sec63 PF02889.16 CDO72825.1 - 3.6e-163 540.8 0.0 1.6e-91 306.0 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CDO72825.1 - 2e-45 154.7 0.1 2.2e-25 89.4 0.1 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CDO72825.1 - 1.1e-36 125.3 0.2 3.6e-36 123.7 0.0 2.1 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 CDO72825.1 - 2e-23 83.2 0.2 4.1e-15 56.2 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDO72825.1 - 5e-15 55.8 0.0 2e-08 34.6 0.0 4.1 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDO72825.1 - 4e-06 27.1 0.2 0.23 11.7 0.1 3.3 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 CDO72825.1 - 0.00016 21.2 0.0 0.0029 17.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 CDO72825.1 - 0.012 14.7 0.0 0.24 10.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Jak1_Phl PF17887.1 CDO72825.1 - 0.094 12.7 0.2 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain DUF4246 PF14033.6 CDO72826.1 - 3.9e-123 411.9 0.0 4.6e-123 411.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) UDG PF03167.19 CDO72827.1 - 5.8e-15 55.6 0.0 1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily GST_N_3 PF13417.6 CDO72828.1 - 7.3e-06 26.3 0.0 1.9e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO72828.1 - 0.021 15.1 0.1 0.061 13.6 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO72828.1 - 0.095 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO72828.1 - 0.11 12.8 0.1 0.25 11.7 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain AMP-binding PF00501.28 CDO72829.1 - 5.4e-40 137.3 0.0 3.1e-24 85.3 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 CDO72829.1 - 1.1e-11 44.9 0.2 2.4e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 CDO72829.1 - 1.8e-07 30.6 10.5 5.9e-05 22.6 0.1 5.8 6 0 0 6 6 6 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CDO72829.1 - 1 9.2 7.3 1.1 9.1 0.6 3.8 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Mis12 PF05859.12 CDO72830.1 - 1.5e-38 131.9 0.2 2e-38 131.5 0.2 1.2 1 0 0 1 1 1 1 Mis12 protein PLN_propep PF16485.5 CDO72830.1 - 0.07 12.8 1.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 Protealysin propeptide Lzipper-MIP1 PF14389.6 CDO72830.1 - 0.14 12.5 1.0 0.45 10.9 1.0 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Cupin_2 PF07883.11 CDO72831.1 - 1.2e-07 31.3 0.1 0.0003 20.4 0.0 2.5 2 0 0 2 2 2 2 Cupin domain DUF4340 PF14238.6 CDO72831.1 - 0.18 11.8 0.1 0.79 9.7 0.0 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4340) CBFD_NFYB_HMF PF00808.23 CDO72832.1 - 8.4e-20 70.8 0.9 1.2e-19 70.3 0.9 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDO72832.1 - 0.0022 18.3 0.1 0.0033 17.8 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 CDO72832.1 - 0.0057 16.7 0.0 0.0099 15.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 CDO72832.1 - 0.21 11.7 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold eIF3_subunit PF08597.10 CDO72833.1 - 0.0034 17.3 2.3 0.0034 17.3 2.3 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit Peptidase_M36 PF02128.15 CDO72836.1 - 1.7e-143 478.3 7.9 2.2e-143 477.9 7.9 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 CDO72836.1 - 7.6e-09 35.3 0.3 2.2e-08 33.8 0.3 1.9 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 CDO72836.1 - 1.1e-05 25.9 1.1 5.1e-05 23.7 0.4 2.3 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain Peptidase_M4_C PF02868.15 CDO72836.1 - 0.00023 21.1 0.0 0.00081 19.3 0.0 1.9 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain DDE_3 PF13358.6 CDO72837.1 - 3e-11 43.3 1.7 5.7e-11 42.4 1.0 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease EF-hand_7 PF13499.6 CDO72837.1 - 0.11 12.9 0.0 0.33 11.4 0.0 1.9 1 1 0 1 1 1 0 EF-hand domain pair Methyltransf_16 PF10294.9 CDO72838.1 - 3.3e-07 30.2 0.0 0.021 14.6 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase RhoGEF PF00621.20 CDO72839.1 - 4.7e-19 69.3 0.3 1.4e-14 54.7 0.1 2.2 2 0 0 2 2 2 2 RhoGEF domain Asn_synthase PF00733.21 CDO72840.1 - 1.9e-96 323.9 0.0 7.9e-57 193.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CDO72840.1 - 1.2e-35 122.1 0.0 1.8e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CDO72840.1 - 8.1e-30 103.8 0.0 1.5e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CDO72840.1 - 0.0031 17.0 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 CDO72840.1 - 0.035 13.2 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 CDO72840.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Aldo_ket_red PF00248.21 CDO72841.1 - 2.6e-57 194.2 0.0 3.2e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PrpR_N PF06506.11 CDO72841.1 - 0.0054 16.3 0.0 0.0099 15.5 0.0 1.3 1 0 0 1 1 1 1 Propionate catabolism activator Aldo_ket_red PF00248.21 CDO72842.1 - 8e-60 202.5 0.0 9.1e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PrpR_N PF06506.11 CDO72842.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Propionate catabolism activator Syntaxin PF00804.25 CDO72843.1 - 2.6e-31 108.8 7.4 5.1e-31 107.9 7.4 1.5 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 CDO72843.1 - 5e-10 39.2 0.1 1.5e-09 37.7 0.1 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 CDO72843.1 - 8.1e-09 35.8 4.8 8.1e-09 35.8 4.8 2.6 3 0 0 3 3 2 1 Syntaxin-like protein FUSC PF04632.12 CDO72843.1 - 0.0013 17.4 3.1 0.0013 17.4 3.1 2.9 2 1 2 4 4 4 1 Fusaric acid resistance protein family Prominin PF05478.11 CDO72843.1 - 0.004 15.2 1.6 0.022 12.7 0.0 2.0 2 0 0 2 2 2 1 Prominin DUF2207 PF09972.9 CDO72843.1 - 0.019 13.8 0.5 0.2 10.4 0.5 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SF3a60_bindingd PF12108.8 CDO72843.1 - 0.033 14.1 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Synaptobrevin PF00957.21 CDO72843.1 - 0.037 13.8 2.1 0.12 12.2 0.2 2.6 2 1 0 2 2 2 0 Synaptobrevin MCPsignal PF00015.21 CDO72843.1 - 0.046 13.5 4.5 0.058 13.2 0.8 2.7 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NDK PF00334.19 CDO72843.1 - 0.094 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Nucleoside diphosphate kinase VitD-bind_III PF09164.10 CDO72843.1 - 0.13 12.3 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III ACC_epsilon PF13822.6 CDO72843.1 - 0.8 10.4 0.1 0.8 10.4 0.1 2.7 3 0 0 3 3 2 0 Acyl-CoA carboxylase epsilon subunit Mod_r PF07200.13 CDO72843.1 - 6.6 6.8 19.3 0.054 13.6 2.8 2.8 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Aminotran_5 PF00266.19 CDO72844.1 - 6.2e-12 45.2 0.0 2.7e-11 43.0 0.0 2.0 2 1 0 2 2 2 1 Aminotransferase class-V Abhydrolase_3 PF07859.13 CDO72846.1 - 0.00012 22.1 2.6 0.00024 21.1 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO72846.1 - 0.12 11.6 0.0 3.7 6.8 0.0 2.8 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Hexapep PF00132.24 CDO72848.1 - 4.8e-15 54.6 12.4 7.5e-07 28.6 2.3 4.5 2 1 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 CDO72848.1 - 8.5e-07 28.8 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 CDO72848.1 - 9.8e-06 25.2 12.3 0.011 15.5 0.7 4.8 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 CDO72848.1 - 5.4e-05 23.6 0.0 8.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 CDO72848.1 - 7.2e-05 21.9 0.1 0.00013 21.0 0.1 1.4 2 0 0 2 2 2 1 L-fucokinase DUF4954 PF16314.5 CDO72848.1 - 0.0008 17.7 1.5 0.0014 16.9 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) PI3K_1B_p101 PF10486.9 CDO72849.1 - 0.0066 14.3 1.8 0.0082 14.0 1.8 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SUR7 PF06687.12 CDO72850.1 - 1e-19 71.0 10.4 1.3e-19 70.7 10.4 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 CDO72850.1 - 8.2 6.3 9.5 0.33 10.9 2.6 2.0 1 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Methyltr_RsmB-F PF01189.17 CDO72851.1 - 7.8e-77 257.4 0.0 1.2e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CDO72851.1 - 2.5e-08 34.3 0.0 1.2e-07 32.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF PCMT PF01135.19 CDO72851.1 - 0.0031 17.3 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CDO72851.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 CDO72851.1 - 0.042 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FUN14 PF04930.15 CDO72852.1 - 4e-20 72.0 1.3 4e-20 72.0 1.3 1.6 2 0 0 2 2 2 1 FUN14 family Adeno_E3_14_5 PF04834.12 CDO72852.1 - 0.32 11.6 2.8 0.59 10.7 2.8 1.5 1 0 0 1 1 1 0 Early E3 14.5 kDa protein CAP_N PF01213.19 CDO72852.1 - 2.8 7.4 7.5 4.2 6.8 7.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Vac7 PF12751.7 CDO72856.1 - 2.5 7.5 6.5 0.23 10.9 0.8 1.8 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 Transposase_21 PF02992.14 CDO72857.1 - 7.8e-08 31.8 0.0 1.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 AAA_lid_8 PF17868.1 CDO72858.1 - 0.086 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA lid domain DUF4229 PF14012.6 CDO72862.1 - 1.1 9.4 0.0 1.1 9.4 0.0 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF4229) ALG3 PF05208.13 CDO72863.1 - 1.2e-109 367.0 13.0 2e-108 363.0 13.0 1.9 1 1 0 1 1 1 1 ALG3 protein Peptidase_M13_N PF05649.13 CDO72864.1 - 4.1e-101 339.4 0.1 6.1e-101 338.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CDO72864.1 - 1.2e-62 211.2 0.0 2.3e-62 210.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 SSP160 PF06933.11 CDO72864.1 - 1.1 7.4 11.6 1.7 6.8 11.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NAGLU PF05089.12 CDO72865.1 - 1.5e-135 451.4 1.5 2.5e-135 450.8 1.5 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 CDO72865.1 - 9.2e-73 245.0 3.1 1.3e-72 244.6 3.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 CDO72865.1 - 1e-19 70.1 0.0 2.3e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF3730 PF12530.8 CDO72865.1 - 0.048 13.2 0.1 0.083 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Scramblase PF03803.15 CDO72866.1 - 1e-56 191.7 0.0 3.4e-56 190.0 0.0 1.7 1 1 0 1 1 1 1 Scramblase zf-Mss51 PF13824.6 CDO72867.1 - 4e-25 87.7 12.5 7.5e-25 86.8 12.5 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.6 CDO72867.1 - 0.13 12.7 6.5 0.24 11.8 6.5 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar 2OG-FeII_Oxy_2 PF13532.6 CDO72868.1 - 3e-15 56.9 0.0 7.2e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HTH_8 PF02954.19 CDO72868.1 - 0.028 14.2 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family IGPD PF00475.18 CDO72869.1 - 4.5e-40 137.3 0.1 1.3e-39 135.8 0.1 1.7 1 1 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF4149 PF13664.6 CDO72869.1 - 0.059 13.7 0.0 0.089 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) SbcCD_C PF13558.6 CDO72869.1 - 0.1 12.8 0.1 0.41 10.9 0.0 1.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CDC45 PF02724.14 CDO72870.1 - 4.4e-228 758.7 0.0 5.2e-228 758.5 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Sec_GG PF07549.14 CDO72870.1 - 0.11 12.0 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif SURF2 PF05477.11 CDO72870.1 - 0.16 11.7 4.2 0.31 10.7 4.2 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop53 PF07767.11 CDO72870.1 - 0.22 10.9 11.2 0.35 10.2 11.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.12 CDO72870.1 - 1 8.7 11.7 2 7.8 11.7 1.3 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 CDO72870.1 - 1.9 8.9 13.7 5.6 7.4 13.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_M24 PF00557.24 CDO72871.1 - 1.2e-47 162.3 0.1 1.6e-47 162.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 CDO72871.1 - 0.0053 17.4 0.0 0.0086 16.7 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DEAD PF00270.29 CDO72872.1 - 8.2e-51 172.2 0.0 1.3e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO72872.1 - 1.7e-30 105.6 0.0 4e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO72872.1 - 4.3e-07 30.1 0.0 6.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDO72872.1 - 0.00012 21.9 0.1 0.00038 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain SP24 PF16504.5 CDO72872.1 - 0.11 12.6 0.5 0.17 11.9 0.5 1.2 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus WD40 PF00400.32 CDO72873.1 - 0.00017 22.3 2.6 3.5 8.6 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat TRAPPC10 PF12584.8 CDO72874.1 - 3.8e-37 127.4 0.0 1.6e-36 125.4 0.0 2.2 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Lyase_1 PF00206.20 CDO72875.1 - 3e-102 342.2 0.0 4.7e-102 341.6 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 CDO72875.1 - 2.5e-24 85.8 0.2 6.1e-24 84.6 0.2 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Syntaxin PF00804.25 CDO72876.1 - 3.2e-33 115.1 10.8 3.2e-33 115.1 10.8 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CDO72876.1 - 2.4e-11 43.5 1.7 2.4e-11 43.5 1.7 2.1 1 1 1 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 CDO72876.1 - 1.6e-06 28.4 10.1 1.6e-06 28.4 10.1 2.6 2 1 0 2 2 2 1 Syntaxin-like protein Use1 PF09753.9 CDO72876.1 - 0.00065 19.5 7.1 0.00072 19.4 6.0 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 Prominin PF05478.11 CDO72876.1 - 0.0017 16.4 2.3 0.0017 16.4 2.3 2.2 2 0 0 2 2 2 1 Prominin MCPsignal PF00015.21 CDO72876.1 - 0.0034 17.2 0.8 0.0034 17.2 0.8 2.4 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain VitD-bind_III PF09164.10 CDO72876.1 - 0.0054 16.7 0.2 0.015 15.3 0.2 1.7 1 0 0 1 1 1 1 Vitamin D binding protein, domain III SKA1 PF07160.12 CDO72876.1 - 0.0066 16.3 1.9 0.0066 16.3 1.9 2.5 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 DUF2207 PF09972.9 CDO72876.1 - 0.0095 14.7 4.0 0.018 13.8 1.2 2.2 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) DUF5383 PF17355.2 CDO72876.1 - 0.02 15.3 2.1 0.031 14.7 0.4 2.2 2 0 0 2 2 1 0 Family of unknown function (DUF5383) V-SNARE PF05008.15 CDO72876.1 - 0.022 15.1 1.3 0.022 15.1 1.3 3.8 2 2 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spectrin PF00435.21 CDO72876.1 - 0.034 14.7 8.9 0.12 12.8 0.1 3.2 3 1 0 3 3 3 0 Spectrin repeat DASH_Dam1 PF08653.10 CDO72876.1 - 0.041 13.7 1.0 0.86 9.5 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 Laminin_II PF06009.12 CDO72876.1 - 0.057 13.4 14.3 0.081 12.9 2.3 2.7 3 0 0 3 3 3 0 Laminin Domain II TPR_2 PF07719.17 CDO72876.1 - 0.12 12.5 1.7 0.19 11.9 0.1 2.2 3 0 0 3 3 1 0 Tetratricopeptide repeat Arc_PepC_II PF06847.11 CDO72876.1 - 0.14 12.7 3.8 0.2 12.2 0.3 2.7 3 1 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II LMBR1 PF04791.16 CDO72876.1 - 0.2 10.5 9.0 0.4 9.5 8.9 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4743 PF15916.5 CDO72876.1 - 0.28 11.2 2.5 0.71 9.8 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4743) ABC_tran_CTD PF16326.5 CDO72876.1 - 0.39 11.0 10.7 0.2 11.9 2.2 3.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain PBP_N PF17093.5 CDO72876.1 - 0.44 10.8 2.5 2.4 8.4 0.1 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus EMP24_GP25L PF01105.24 CDO72876.1 - 0.9 9.4 8.5 0.64 9.9 1.4 2.8 2 2 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.11 CDO72876.1 - 0.96 9.9 7.1 34 4.9 3.6 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.11 CDO72876.1 - 0.99 8.9 6.8 1.8 8.0 1.6 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Tweety PF04906.13 CDO72876.1 - 1.5 7.4 10.2 0.032 12.9 1.5 2.2 2 1 1 3 3 3 0 Tweety Baculo_PEP_C PF04513.12 CDO72876.1 - 1.7 8.7 15.8 0.46 10.5 1.6 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Orf78 PF06024.12 CDO72876.1 - 2.3 8.6 6.0 0.29 11.4 0.7 2.4 2 1 0 2 2 2 0 Orf78 (ac78) UL45 PF05473.12 CDO72876.1 - 2.5 7.7 5.1 0.94 9.1 1.3 2.1 2 1 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like MMPL PF03176.15 CDO72876.1 - 2.7 6.9 5.4 0.53 9.2 1.0 2.0 2 0 0 2 2 2 0 MMPL family DUF1664 PF07889.12 CDO72876.1 - 2.8 8.0 11.5 0.95 9.5 1.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) COG2 PF06148.11 CDO72876.1 - 3 7.9 8.6 3 7.9 0.2 3.3 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 PCRF PF03462.18 CDO72876.1 - 3.5 7.5 12.7 0.33 10.8 2.3 2.8 1 1 2 3 3 3 0 PCRF domain Lebercilin PF15619.6 CDO72876.1 - 4.1 7.0 15.6 0.59 9.8 1.5 2.7 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TMPIT PF07851.13 CDO72876.1 - 9.2 5.4 11.7 0.62 9.3 0.7 2.5 2 1 0 2 2 2 0 TMPIT-like protein zf-AN1 PF01428.16 CDO72877.1 - 5e-11 42.6 7.7 5e-11 42.6 7.7 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Rubredoxin_2 PF18073.1 CDO72877.1 - 0.09 12.5 0.4 0.09 12.5 0.4 2.3 4 0 0 4 4 4 0 Rubredoxin metal binding domain IBR PF01485.21 CDO72877.1 - 0.4 10.9 9.5 0.55 10.5 8.6 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 CDO72877.1 - 0.49 10.2 7.9 0.11 12.3 4.2 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Aminotran_1_2 PF00155.21 CDO72878.1 - 3.7e-82 276.4 0.0 4.3e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HEAT PF02985.22 CDO72879.1 - 7.6e-18 63.1 20.5 0.0004 20.4 0.1 8.8 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 CDO72879.1 - 4.1e-12 46.3 16.3 0.00023 21.5 0.0 6.3 5 1 1 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 CDO72879.1 - 7.7e-10 39.1 20.4 0.0016 18.9 3.5 6.1 5 1 1 6 6 6 4 HEAT-like repeat Cnd1 PF12717.7 CDO72879.1 - 0.00039 20.5 0.2 0.85 9.6 0.0 3.6 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Ist1 PF03398.14 CDO72881.1 - 1.1e-38 132.7 0.1 1.8e-38 132.1 0.1 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.18 CDO72881.1 - 6.4e-09 35.8 1.1 4.8e-08 32.9 0.0 2.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF1697 PF08002.11 CDO72881.1 - 0.0024 18.3 0.1 0.0073 16.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1697) Cellulase PF00150.18 CDO72882.1 - 9.8e-13 48.2 0.0 2.2e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GTP_EFTU PF00009.27 CDO72883.1 - 1.2e-36 126.1 2.3 4.8e-35 120.9 2.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDO72883.1 - 1.4e-30 105.5 1.1 3.7e-30 104.1 1.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CDO72883.1 - 5.9e-08 32.8 0.3 2.5e-07 30.8 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CDO72883.1 - 0.00032 20.5 0.5 0.14 11.9 0.1 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 CDO72883.1 - 0.00042 19.4 1.9 0.00072 18.6 0.3 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 CDO72883.1 - 0.0032 17.0 0.0 0.0093 15.4 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 CDO72883.1 - 0.014 15.0 0.8 0.082 12.4 0.8 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 CDO72883.1 - 0.018 14.5 0.0 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 CDO72883.1 - 0.053 13.7 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase CHORD PF04968.12 CDO72884.1 - 2.9e-47 159.2 23.1 2.3e-27 95.5 5.0 3.5 2 1 1 3 3 3 3 CHORD CS PF04969.16 CDO72884.1 - 1.6e-14 54.6 0.0 3e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 CS domain Rieske PF00355.26 CDO72884.1 - 0.21 11.5 6.4 1.3 9.0 0.6 2.4 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain Mito_carr PF00153.27 CDO72885.1 - 6.3e-05 22.8 0.0 0.036 14.0 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Helicase_C PF00271.31 CDO72886.1 - 1.4e-16 60.8 0.0 2.4e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CDO72886.1 - 0.016 15.9 2.2 0.04 14.6 2.2 1.7 1 0 0 1 1 1 0 RecQ zinc-binding DEAD PF00270.29 CDO72886.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Enterotoxin_ST PF02048.16 CDO72886.1 - 0.43 11.1 2.2 3.7 8.1 2.6 2.3 2 0 0 2 2 2 0 Heat-stable enterotoxin ST WD40 PF00400.32 CDO72889.1 - 1e-36 124.3 17.6 5.2e-12 46.1 0.2 8.4 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO72889.1 - 5.6e-10 39.4 0.1 0.0022 18.3 0.1 5.2 3 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CDO72889.1 - 2.3e-05 23.3 2.4 0.015 14.1 0.0 4.2 4 2 2 6 6 6 1 Nup133 N terminal like Nup160 PF11715.8 CDO72889.1 - 4.4e-05 22.3 1.2 3.9 6.0 0.1 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.11 CDO72889.1 - 7.5e-05 22.6 0.1 0.2 11.3 0.0 2.5 2 0 0 2 2 2 2 TUP1-like enhancer of split Ge1_WD40 PF16529.5 CDO72889.1 - 0.00054 19.0 0.1 2.7 6.9 0.0 3.5 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CDO72889.1 - 0.0085 15.1 0.1 0.027 13.4 0.1 1.8 1 1 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 CDO72889.1 - 0.21 9.9 0.0 0.31 9.3 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz GATase_2 PF00310.21 CDO72890.1 - 1.1e-175 584.4 0.0 1.5e-175 584.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CDO72890.1 - 3.7e-156 519.9 0.0 5.7e-156 519.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CDO72890.1 - 6.4e-116 386.7 0.0 1.1e-114 382.7 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CDO72890.1 - 3.9e-88 294.0 3.2 6.7e-88 293.3 3.2 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 CDO72890.1 - 8.1e-27 94.2 0.0 4.7e-26 91.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CDO72890.1 - 6.6e-22 77.4 0.1 1.3e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_3 PF13738.6 CDO72890.1 - 2.4e-08 33.6 0.6 0.2 10.9 0.0 3.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDO72890.1 - 4.4e-08 33.6 0.0 0.0013 19.2 0.0 4.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO72890.1 - 1.9e-07 31.2 0.0 7.3e-07 29.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDO72890.1 - 1.6e-05 24.7 0.2 0.0051 16.4 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CDO72890.1 - 4.6e-05 22.3 1.1 0.00013 20.8 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 CDO72890.1 - 0.00028 20.3 0.2 0.081 12.2 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 CDO72890.1 - 0.00044 19.7 0.0 0.0008 18.8 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 CDO72890.1 - 0.00082 18.6 1.2 0.0073 15.4 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 CDO72890.1 - 0.0031 16.9 0.1 0.0031 16.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CDO72890.1 - 0.0062 17.0 0.4 2.7 8.5 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CDO72890.1 - 0.0099 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMN_dh PF01070.18 CDO72890.1 - 0.012 14.6 0.6 0.095 11.7 1.3 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lycopene_cycl PF05834.12 CDO72890.1 - 0.038 13.0 0.0 2.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 CDO72890.1 - 0.048 12.9 0.4 0.19 10.9 0.0 2.0 2 0 0 2 2 2 0 Thi4 family GATase_6 PF13522.6 CDO72890.1 - 0.065 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain GIDA PF01134.22 CDO72890.1 - 0.091 11.8 1.4 0.59 9.1 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 CDO72890.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 CDO72890.1 - 0.13 11.6 0.2 0.77 9.1 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CDO72890.1 - 0.18 11.8 0.0 69 3.5 0.0 3.8 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Acetyltransf_13 PF13880.6 CDO72891.1 - 1.6e-15 56.8 0.0 3.1e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 CDO72891.1 - 2.7e-09 36.7 0.1 4.5e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 CDO72891.1 - 0.00061 20.2 0.0 0.0072 16.7 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO72891.1 - 0.022 15.0 0.0 0.047 13.9 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDO72891.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.29 CDO72892.1 - 7.9e-33 113.7 0.1 1.3e-15 57.6 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase DUF4217 PF13959.6 CDO72892.1 - 2.2e-24 85.4 1.3 3.6e-24 84.8 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 CDO72892.1 - 1.4e-19 70.5 0.0 7.1e-19 68.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CDO72892.1 - 0.034 14.4 0.5 2.9 8.2 0.4 3.1 2 1 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 CDO72892.1 - 0.041 13.1 0.4 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase SBF_like PF13593.6 CDO72892.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) SOG2 PF10428.9 CDO72893.1 - 4.7e-94 316.4 0.4 1.3e-91 308.4 0.0 3.0 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.6 CDO72893.1 - 7.9e-10 38.3 6.0 8e-06 25.5 0.4 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CDO72893.1 - 1.5e-09 38.0 0.6 3.2e-05 24.2 0.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDO72893.1 - 0.0055 16.2 1.4 0.0098 15.4 1.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeat Perilipin PF03036.16 CDO72893.1 - 0.051 12.6 0.5 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Perilipin family LRR_1 PF00560.33 CDO72893.1 - 1.2 9.9 6.4 17 6.4 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat FYVE PF01363.21 CDO72894.1 - 9.6e-18 64.1 1.1 1.6e-17 63.4 1.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 CDO72894.1 - 2.1e-16 59.3 1.7 5.8e-16 57.9 1.7 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.13 CDO72894.1 - 0.0043 17.0 7.9 0.0075 16.2 5.8 2.1 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type FYVE_2 PF02318.16 CDO72894.1 - 0.17 12.1 1.7 0.21 11.8 0.6 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_2 PF14445.6 CDO72894.1 - 0.36 11.0 1.3 0.71 10.1 1.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Cofilin_ADF PF00241.20 CDO72895.1 - 5.3e-35 119.9 0.0 3.7e-16 59.0 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein CoA_trans PF01144.23 CDO72896.1 - 4.8e-105 349.8 0.7 3e-63 213.1 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CDO72896.1 - 0.0017 18.3 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 CDO72896.1 - 0.0031 17.5 0.3 0.04 13.9 0.0 2.7 3 1 0 3 3 3 1 Acetyl-CoA hydrolase/transferase N-terminal domain CoA_trans PF01144.23 CDO72897.1 - 1.5e-95 318.7 3.7 1.3e-54 184.9 0.6 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CDO72897.1 - 0.045 13.7 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain SMI1_KNR4 PF09346.10 CDO72898.1 - 7.7e-18 65.2 0.0 1.4e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) HSA PF07529.13 CDO72899.1 - 7e-14 51.9 0.7 7e-14 51.9 0.7 2.8 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 CDO72899.1 - 1.8e-10 40.9 0.4 4.6e-10 39.6 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CDO72899.1 - 6.8e-09 35.8 0.6 1.7e-08 34.5 0.6 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cellulase PF00150.18 CDO72901.1 - 1e-12 48.1 0.0 2.1e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF515 PF04415.12 CDO72901.1 - 0.024 13.0 1.6 0.023 13.1 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF515) Pectate_lyase_3 PF12708.7 CDO72902.1 - 2.8e-90 301.9 14.5 3.5e-75 252.5 8.6 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 CDO72902.1 - 6.5e-07 28.9 0.6 0.0073 16.0 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase zf-CCCH_4 PF18044.1 CDO72903.1 - 0.0011 18.8 2.9 0.0018 18.0 2.9 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Fib_alpha PF08702.10 CDO72903.1 - 0.008 16.4 1.1 0.008 16.4 1.1 3.4 4 1 1 5 5 4 1 Fibrinogen alpha/beta chain family DctP PF03480.13 CDO72903.1 - 0.03 13.7 0.3 0.03 13.7 0.3 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 zf-CCCH_2 PF14608.6 CDO72903.1 - 0.051 14.1 0.8 0.089 13.3 0.8 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Ins_allergen_rp PF06757.13 CDO72903.1 - 0.052 13.5 0.3 0.13 12.2 0.3 1.6 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification DUF3095 PF11294.8 CDO72903.1 - 0.17 10.9 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) zf-CCCH PF00642.24 CDO72903.1 - 0.67 9.9 4.3 0.15 12.0 1.0 1.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FapA PF03961.13 CDO72903.1 - 0.73 8.4 6.5 0.23 10.0 1.5 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A Lectin_N PF03954.14 CDO72903.1 - 0.79 9.5 13.2 2.4 7.9 0.7 2.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain IFT57 PF10498.9 CDO72903.1 - 0.95 8.4 10.9 0.63 8.9 3.3 2.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 zf_CCCH_4 PF18345.1 CDO72903.1 - 0.97 9.6 2.7 1.6 8.9 2.7 1.3 1 0 0 1 1 1 0 Zinc finger domain Phage_GPO PF05929.11 CDO72903.1 - 0.98 9.0 9.1 0.29 10.7 2.0 2.5 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase OmpH PF03938.14 CDO72903.1 - 1.4 9.2 27.2 0.21 11.9 10.2 3.9 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) Vma12 PF11712.8 CDO72903.1 - 1.5 8.9 6.1 0.14 12.2 0.7 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ZnuA PF01297.17 CDO72903.1 - 1.7 8.0 4.1 4 6.8 3.2 2.1 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic YabA PF06156.13 CDO72903.1 - 4.4 8.0 13.7 0.6 10.8 5.8 3.2 4 0 0 4 4 3 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 CDO72903.1 - 8.3 6.5 9.1 14 5.8 0.2 4.0 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.27 CDO72904.1 - 6.6e-06 26.7 0.0 9.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CDO72904.1 - 0.0056 16.1 0.0 0.0064 16.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CDO72904.1 - 0.028 14.6 0.0 0.51 10.6 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Porin_3 PF01459.22 CDO72905.1 - 2.1e-81 273.4 2.4 2.4e-81 273.2 2.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin HSP70 PF00012.20 CDO72906.1 - 1.5e-264 878.8 2.3 1.7e-264 878.6 2.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CDO72906.1 - 2.3e-16 59.5 0.1 3.8e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CDO72906.1 - 0.0029 17.4 0.0 0.0077 16.0 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CDO72906.1 - 0.021 14.1 0.2 0.053 12.8 0.2 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase SWI-SNF_Ssr4 PF08549.10 CDO72906.1 - 3.2 6.3 5.2 20 3.6 3.0 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) PhoD PF09423.10 CDO72907.1 - 6.3e-88 295.1 1.6 1e-60 205.6 0.1 2.0 2 0 0 2 2 2 2 PhoD-like phosphatase PhoD_N PF16655.5 CDO72907.1 - 5.9e-22 78.0 0.0 1.3e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 CDO72907.1 - 0.0045 17.5 0.1 0.013 16.1 0.0 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain AAA_33 PF13671.6 CDO72907.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PNGaseA PF12222.8 CDO72908.1 - 7.1e-140 466.7 1.8 9.1e-140 466.3 1.8 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A HTH_45 PF14947.6 CDO72908.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix Pmp3 PF01679.17 CDO72909.1 - 2.6e-16 59.5 4.7 3.5e-16 59.1 4.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NPR3 PF03666.13 CDO72909.1 - 1.1 8.0 3.6 1.9 7.2 3.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Med19 PF10278.9 CDO72909.1 - 6.2 6.7 11.7 1.2 9.1 7.8 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 FBPase PF00316.20 CDO72911.1 - 6.5e-74 247.5 0.2 8.4e-74 247.1 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 CDO72911.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family DUF2418 PF10332.9 CDO72912.1 - 2.7e-13 50.2 0.0 4.5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF3552 PF12072.8 CDO72913.1 - 0.043 13.2 5.8 0.065 12.6 2.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Lzipper-MIP1 PF14389.6 CDO72913.1 - 3.2 8.1 6.6 2.9 8.3 0.0 3.4 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 Spc7 PF08317.11 CDO72914.1 - 0.0034 16.3 2.6 0.0034 16.3 2.6 3.2 3 0 0 3 3 3 1 Spc7 kinetochore protein DUF812 PF05667.11 CDO72914.1 - 0.0049 15.8 4.5 0.0049 15.8 4.5 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF812) Fib_alpha PF08702.10 CDO72914.1 - 0.043 14.0 0.4 0.043 14.0 0.4 2.8 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CDO72914.1 - 0.19 11.8 2.2 5.1 7.1 0.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 CDO72914.1 - 0.76 8.3 10.7 0.033 12.8 1.6 2.2 2 0 0 2 2 2 0 AAA domain NPV_P10 PF05531.12 CDO72914.1 - 1.4 9.4 8.1 0.65 10.5 0.4 3.7 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.21 CDO72914.1 - 1.8 9.1 25.7 0.07 13.6 5.8 4.0 3 1 0 3 3 3 0 Spectrin repeat Jnk-SapK_ap_N PF09744.9 CDO72914.1 - 2.8 8.2 27.4 0.06 13.6 4.4 3.4 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 CDO72914.1 - 8.7 6.4 25.5 0.025 14.6 5.2 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prenyltransf PF01255.19 CDO72915.1 - 1.2e-72 244.1 0.0 1.4e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase zf-RING_2 PF13639.6 CDO72916.1 - 3.4e-05 24.1 4.8 3.4e-05 24.1 4.8 2.0 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.17 CDO72916.1 - 0.00012 21.6 0.4 0.00022 20.8 0.4 1.5 1 0 0 1 1 1 1 SWIM zinc finger Prok-RING_1 PF14446.6 CDO72916.1 - 0.0039 17.1 1.3 0.0039 17.1 1.3 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.29 CDO72916.1 - 0.011 15.6 5.5 0.022 14.7 5.5 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 CDO72916.1 - 0.032 14.1 2.2 0.032 14.1 2.2 2.2 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.6 CDO72916.1 - 0.044 13.6 4.8 0.099 12.5 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EGF_alliinase PF04863.13 CDO72916.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.3 2 0 0 2 2 2 0 Alliinase EGF-like domain FANCL_C PF11793.8 CDO72916.1 - 0.2 11.9 6.2 0.27 11.5 4.6 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain Aldolase_II PF00596.21 CDO72917.1 - 1.1e-49 168.9 0.3 1.6e-49 168.4 0.3 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FTHFS PF01268.19 CDO72918.1 - 2e-261 868.0 0.1 3.5e-261 867.3 0.0 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CDO72918.1 - 5.1e-68 227.4 0.2 5.1e-68 227.4 0.2 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CDO72918.1 - 2.8e-39 134.0 0.8 8.6e-39 132.4 0.8 1.9 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Prefoldin PF02996.17 CDO72918.1 - 0.057 13.3 0.0 1.9 8.4 0.0 2.8 2 0 0 2 2 2 0 Prefoldin subunit ABATE PF07336.11 CDO72918.1 - 0.35 11.5 2.7 1.1 9.9 0.7 2.6 2 0 0 2 2 2 0 Putative stress-induced transcription regulator GrpE PF01025.19 CDO72919.1 - 1.1e-43 148.8 0.9 2.4e-43 147.7 0.9 1.6 1 1 0 1 1 1 1 GrpE tRNA-synt_2d PF01409.20 CDO72920.1 - 1.1e-45 156.1 0.0 5e-26 91.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CDO72920.1 - 7.1e-06 26.4 0.0 1.8e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain ThiF PF00899.21 CDO72921.1 - 3.1e-47 161.0 0.0 4.2e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 CDO72921.1 - 2.7e-29 101.1 0.0 4.2e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain HypA PF01155.19 CDO72921.1 - 0.11 12.6 0.2 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Shikimate_DH PF01488.20 CDO72921.1 - 0.14 12.2 0.3 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.8 CDO72921.1 - 0.15 12.2 2.8 0.34 11.1 2.8 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein RTC PF01137.21 CDO72922.1 - 1.1e-58 198.1 0.1 1.3e-58 197.9 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CDO72922.1 - 9.6e-13 48.5 1.7 1.4e-10 41.6 0.1 2.3 1 1 1 2 2 2 2 RNA 3'-terminal phosphate cyclase (RTC), insert domain NPR2 PF06218.11 CDO72923.1 - 3.1e-90 303.0 3.7 1.6e-48 165.5 1.1 3.4 2 1 2 4 4 4 3 Nitrogen permease regulator 2 ATG16 PF08614.11 CDO72923.1 - 0.44 10.8 2.3 0.32 11.2 0.1 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) GCIP PF13324.6 CDO72924.1 - 2.1e-37 129.2 0.0 3.7e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Torus PF16131.5 CDO72924.1 - 2.1e-06 28.4 0.1 4.3e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 CDO72924.1 - 1.5e-05 24.8 2.7 1.5e-05 24.8 2.7 2.3 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 CDO72924.1 - 0.00065 19.5 1.3 0.0015 18.4 1.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CDO72924.1 - 0.0015 18.8 0.1 0.0042 17.3 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 CDO72924.1 - 0.052 13.4 1.5 0.13 12.1 1.5 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CDO72924.1 - 0.091 13.3 1.5 0.23 12.0 1.5 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RRM_occluded PF16842.5 CDO72924.1 - 0.11 12.4 0.0 0.78 9.6 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif GMC_oxred_N PF00732.19 CDO72925.1 - 3.1e-42 145.0 0.0 7.9e-42 143.6 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO72925.1 - 8.6e-27 94.4 0.0 1.4e-20 74.3 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.24 CDO72925.1 - 3.4e-05 23.6 3.6 0.00051 19.7 2.3 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDO72925.1 - 0.0014 18.9 0.2 0.0037 17.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CDO72925.1 - 0.0027 16.8 0.1 0.0044 16.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CDO72925.1 - 0.0081 15.3 2.0 0.048 12.7 1.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CDO72925.1 - 0.044 13.0 0.2 0.13 11.4 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO72925.1 - 0.066 12.4 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 CDO72925.1 - 0.074 11.7 0.2 0.11 11.1 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pkinase PF00069.25 CDO72926.1 - 5.4e-05 22.7 0.0 7.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDO72926.1 - 0.00031 19.6 0.0 0.00045 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO72926.1 - 0.0011 18.9 0.2 0.0013 18.7 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDO72926.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDO72926.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 CDO72926.1 - 0.2 10.9 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PBP1_TM PF14812.6 CDO72927.1 - 1.1 9.7 27.3 0.11 12.9 5.3 3.9 2 2 2 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OGG_N PF07934.12 CDO72928.1 - 8.7e-29 100.1 0.0 1.3e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CDO72928.1 - 1.4e-14 54.5 0.0 2.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CDO72928.1 - 0.045 13.7 0.1 0.54 10.2 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif NMT_C PF02799.15 CDO72929.1 - 3.8e-80 268.3 0.0 5.8e-80 267.7 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CDO72929.1 - 8.3e-66 220.8 0.0 1.6e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 CDO72929.1 - 2.9e-05 24.2 0.0 0.00053 20.1 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain DUF3292 PF11696.8 CDO72929.1 - 0.13 10.6 4.7 0.19 10.1 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) GRA6 PF05084.13 CDO72929.1 - 1.8 8.5 5.6 3 7.7 5.6 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) UFD1 PF03152.14 CDO72930.1 - 4.3e-64 215.1 0.0 6e-64 214.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 CDO72930.1 - 0.028 14.2 0.1 0.09 12.6 0.0 1.8 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Cpn60_TCP1 PF00118.24 CDO72931.1 - 6.3e-149 496.7 13.5 7.2e-149 496.6 13.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Vps52 PF04129.12 CDO72931.1 - 0.043 12.6 0.2 0.2 10.4 0.2 1.8 2 0 0 2 2 2 0 Vps52 / Sac2 family HSL_N PF06350.12 CDO72931.1 - 0.11 11.4 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus DUF1491 PF07372.12 CDO72932.1 - 0.072 13.5 0.0 0.099 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) Adaptin_N PF01602.20 CDO72933.1 - 0.00087 18.0 0.0 0.001 17.7 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Arteri_nucleo PF01481.16 CDO72933.1 - 0.053 13.8 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein RabGAP-TBC PF00566.18 CDO72934.1 - 5e-40 137.5 0.0 6.6e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mito_carr PF00153.27 CDO72935.1 - 8.7e-45 150.6 1.4 2.2e-15 56.3 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Rrn6 PF10214.9 CDO72935.1 - 0.0019 16.8 2.3 0.0025 16.4 2.3 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Ribosomal_L3 PF00297.22 CDO72937.1 - 1.5e-23 83.4 2.5 4.4e-21 75.3 0.7 2.4 1 1 2 3 3 3 2 Ribosomal protein L3 DUF2981 PF11200.8 CDO72938.1 - 1.4 8.6 5.8 1.2 8.8 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) SOG2 PF10428.9 CDO72938.1 - 2.4 7.2 24.4 3.2 6.8 24.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TrkA_C PF02080.21 CDO72939.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain MFS_1 PF07690.16 CDO72941.1 - 3.8e-34 118.2 51.9 1.8e-20 73.2 7.6 3.9 3 1 0 3 3 3 3 Major Facilitator Superfamily DUF4611 PF15387.6 CDO72941.1 - 0.17 12.1 0.0 1.1 9.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SafA PF17073.5 CDO72941.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Two-component-system connector protein Cofilin_ADF PF00241.20 CDO72942.1 - 5.1e-18 65.0 0.0 5.7e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mannosyl_trans PF05007.13 CDO72943.1 - 1.5e-77 261.0 11.9 1.8e-77 260.7 11.9 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CDO72943.1 - 1.6e-08 34.0 2.5 1.6e-08 34.0 2.5 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Arf PF00025.21 CDO72944.1 - 2.4e-43 147.6 0.0 8.9e-36 123.0 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 CDO72944.1 - 0.00023 20.7 0.0 0.0049 16.3 0.0 2.0 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CDO72944.1 - 0.0064 15.7 0.1 0.067 12.3 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Retrotran_gag_2 PF14223.6 CDO72946.1 - 2.7e-29 101.6 0.0 4.4e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO72946.1 - 2.4e-05 24.2 4.8 6.8e-05 22.8 4.8 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF4219 PF13961.6 CDO72946.1 - 7.9e-05 22.2 0.3 0.00014 21.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC_5 PF14787.6 CDO72946.1 - 0.00023 20.8 3.9 0.00058 19.5 3.9 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Retrotran_gag_3 PF14244.6 CDO72946.1 - 0.0094 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 CDO72946.1 - 0.018 14.7 2.4 0.04 13.7 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 CDO72946.1 - 0.083 13.3 0.7 0.16 12.4 0.7 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G RVT_2 PF07727.14 CDO72947.1 - 9.1e-62 208.9 0.0 1.2e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO72947.1 - 1.6e-15 57.3 0.1 8.5e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDO72947.1 - 0.018 14.8 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF4123 PF13503.6 CDO72947.1 - 0.097 13.1 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) ABC1 PF03109.16 CDO72948.1 - 1e-22 80.5 0.0 4e-13 49.6 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 CDO72948.1 - 0.022 14.7 0.4 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Peptidase_C48 PF02902.19 CDO72949.1 - 0.0012 18.7 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_transf_8 PF01501.20 CDO72950.1 - 3.2e-24 85.9 0.0 7.2e-24 84.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Apolipoprotein PF01442.18 CDO72951.1 - 0.0011 18.9 4.9 0.0011 18.9 4.9 2.1 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.18 CDO72951.1 - 0.24 11.5 24.6 0.1 12.7 4.8 2.2 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) SCAB_CC PF16712.5 CDO72951.1 - 2.4 7.9 13.2 2.1 8.1 0.4 3.2 1 1 2 3 3 3 0 Coiled-coil regions of plant-specific actin-binding protein MFS_1 PF07690.16 CDO72952.1 - 3e-44 151.4 27.3 3e-44 151.4 27.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO72952.1 - 1e-13 51.0 5.2 2.3e-13 49.9 5.2 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter TrbL PF04610.14 CDO72953.1 - 0.28 10.9 1.5 0.51 10.1 1.5 1.4 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Mating_N PF12731.7 CDO72954.1 - 1.5e-06 28.2 3.1 3.3e-06 27.1 3.1 1.6 1 0 0 1 1 1 1 Mating-type protein beta 1 PPV_E2_N PF00508.17 CDO72954.1 - 0.24 10.7 0.1 0.36 10.1 0.1 1.2 1 0 0 1 1 1 0 E2 (early) protein, N terminal Peptidase_M3 PF01432.20 CDO72955.1 - 8.6e-124 414.3 0.0 1.1e-123 413.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 CUT PF02376.15 CDO72955.1 - 0.06 13.5 0.0 0.29 11.3 0.0 2.2 1 1 0 1 1 1 0 CUT domain Peptidase_M91 PF14891.6 CDO72955.1 - 0.19 12.0 0.1 0.42 10.9 0.1 1.5 1 0 0 1 1 1 0 Effector protein WSD PF15613.6 CDO72956.1 - 0.0058 17.1 0.7 0.014 15.9 0.8 1.8 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif NOA36 PF06524.12 CDO72956.1 - 4.5 6.5 6.8 7.5 5.8 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1754 PF08555.10 CDO72957.1 - 3.3e-14 53.5 8.2 5.9e-14 52.6 8.2 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF4191 PF13829.6 CDO72957.1 - 0.0016 17.8 0.2 0.0027 17.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) SR-25 PF10500.9 CDO72957.1 - 0.024 14.3 12.7 0.03 13.9 12.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1751 PF08551.10 CDO72958.1 - 2.4e-24 85.8 5.6 5e-24 84.8 5.6 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Vps51 PF08700.11 CDO72958.1 - 2.6e-14 53.1 0.5 6.9e-14 51.7 0.5 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Vps5 PF09325.10 CDO72958.1 - 0.12 11.9 0.7 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 Vps5 C terminal like KxDL PF10241.9 CDO72958.1 - 0.14 12.4 0.7 0.54 10.6 0.7 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein Rhomboid PF01694.22 CDO72958.1 - 0.44 10.6 9.2 1 9.3 9.2 1.6 1 0 0 1 1 1 0 Rhomboid family SecE PF00584.20 CDO72960.1 - 6.2e-16 58.1 0.0 7.2e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex PPR_2 PF13041.6 CDO72961.1 - 7.4e-19 67.7 0.2 0.00092 19.4 0.0 7.9 3 2 4 7 7 7 6 PPR repeat family PPR PF01535.20 CDO72961.1 - 8.8e-11 41.3 9.3 0.029 14.6 0.1 8.1 9 1 0 9 9 9 3 PPR repeat PPR_long PF17177.4 CDO72961.1 - 8.5e-07 28.5 0.0 0.00059 19.3 0.0 3.4 2 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CDO72961.1 - 0.00013 21.6 4.0 0.02 14.6 0.0 5.1 7 0 0 7 7 7 1 PPR repeat PPR_3 PF13812.6 CDO72961.1 - 0.00024 21.1 0.0 18 5.5 0.0 5.8 7 1 1 8 8 8 2 Pentatricopeptide repeat domain TPR_19 PF14559.6 CDO72961.1 - 0.019 15.4 0.2 0.52 10.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat GDC-P PF02347.16 CDO72962.1 - 1e-180 601.2 0.0 3.1e-171 570.0 0.0 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 CDO72962.1 - 7.7e-05 22.1 0.1 0.00014 21.2 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CDO72962.1 - 0.00011 21.3 0.1 0.00046 19.2 0.1 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DUF1741 PF08427.10 CDO72963.1 - 3.6e-23 82.4 0.5 6e-21 75.2 0.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1741) zf-C2H2_4 PF13894.6 CDO72964.1 - 3.7 8.6 6.1 26 6.0 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger F-box-like PF12937.7 CDO72965.1 - 7e-06 25.8 0.0 2.1e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO72965.1 - 0.028 14.3 0.0 0.095 12.6 0.0 2.0 1 0 0 1 1 1 0 F-box domain TPT PF03151.16 CDO72967.1 - 5.3e-09 35.8 17.7 1.1e-08 34.9 17.7 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF5381 PF17353.2 CDO72967.1 - 0.017 14.9 0.2 0.058 13.1 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5381) O-FucT PF10250.9 CDO72968.1 - 3.6e-10 40.1 0.0 5.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase YccV-like PF08755.11 CDO72969.1 - 0.075 13.6 0.2 0.32 11.5 0.0 2.1 2 0 0 2 2 2 0 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 CDO72970.1 - 3.4e-06 26.7 0.0 6.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 CDO72970.1 - 0.0053 16.6 0.1 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 F-box-like ApbA_C PF08546.11 CDO72971.1 - 2.1e-26 92.5 0.0 3e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CDO72971.1 - 3.3e-21 75.5 0.0 1.9e-20 73.1 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.21 CDO72972.1 - 6.2e-44 150.4 0.0 9.1e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family PB1 PF00564.24 CDO72973.1 - 9e-09 35.2 0.0 1.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Baculo_PEP_C PF04513.12 CDO72973.1 - 0.21 11.6 0.2 2 8.5 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 CDO72973.1 - 4.2 8.1 10.6 9.2 6.9 0.4 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) F-box-like PF12937.7 CDO72974.1 - 2.3e-09 37.0 0.9 7.3e-09 35.4 0.9 2.0 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 CDO72974.1 - 0.22 11.5 2.0 6.6 6.8 0.4 3.3 2 1 0 2 2 2 0 F-box-like domain Homeodomain PF00046.29 CDO72975.1 - 2e-12 46.8 0.3 3.4e-12 46.0 0.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDO72975.1 - 0.00079 19.3 0.1 0.0015 18.3 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF4962 PF16332.5 CDO72976.1 - 1.9e-05 23.4 1.0 3.6e-05 22.4 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4962) DUF4448 PF14610.6 CDO72976.1 - 0.0018 18.1 0.0 0.97 9.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) TPPK_C PF12555.8 CDO72976.1 - 0.45 10.6 4.3 0.43 10.7 0.2 2.9 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Homeodomain PF00046.29 CDO72977.1 - 6.2e-07 29.2 0.3 1.2e-06 28.2 0.3 1.5 1 0 0 1 1 1 1 Homeodomain Rrn6 PF10214.9 CDO72977.1 - 9 4.6 7.7 4.5 5.6 5.8 1.5 1 1 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor WD40 PF00400.32 CDO72978.1 - 2.9e-20 72.2 6.8 0.0065 17.3 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO72978.1 - 2.3e-08 34.2 0.0 0.085 13.2 0.0 5.3 3 3 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Zn_clus PF00172.18 CDO72979.1 - 7e-06 26.1 7.0 1.3e-05 25.2 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CDO72979.1 - 0.043 12.8 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF812 PF05667.11 CDO72980.1 - 0.0011 17.9 20.5 0.0011 17.9 20.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF812) BBP1_C PF15272.6 CDO72980.1 - 0.01 15.7 15.4 0.01 15.7 15.4 2.7 2 1 1 3 3 3 0 Spindle pole body component BBP1, C-terminal SHE3 PF17078.5 CDO72980.1 - 0.99 9.1 29.3 0.89 9.2 17.4 2.9 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 DUF4239 PF14023.6 CDO72980.1 - 1 9.0 10.7 0.17 11.6 6.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4239) DUF1515 PF07439.11 CDO72980.1 - 1.2 9.1 8.3 5.2 7.1 3.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF1664 PF07889.12 CDO72980.1 - 1.5 8.9 17.1 5.2 7.1 6.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3439 PF11921.8 CDO72980.1 - 1.7 8.6 7.9 2.7 8.0 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) UPF0242 PF06785.11 CDO72980.1 - 6.3 6.8 43.5 0.48 10.5 30.5 3.5 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus UPF0542 PF15086.6 CDO72980.1 - 8.9 6.3 7.8 27 4.8 7.8 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Sec3_C PF09763.9 CDO72981.1 - 1.1e-119 400.8 15.4 7.3e-100 335.4 0.4 3.0 1 1 2 3 3 3 3 Exocyst complex component Sec3 Glyco_transf_21 PF13506.6 CDO72982.1 - 2.3e-26 92.3 3.2 1.7e-20 73.2 0.1 2.9 3 1 0 3 3 3 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CDO72982.1 - 6e-15 55.8 0.0 7.7e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CDO72982.1 - 2.2e-07 30.8 0.0 4.6e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 F-box-like PF12937.7 CDO72983.1 - 9.2e-09 35.1 0.0 3.2e-08 33.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 CDO72983.1 - 0.01 16.2 2.0 2.5 9.0 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat F-box PF00646.33 CDO72983.1 - 0.036 14.0 0.0 0.17 11.8 0.0 2.2 1 0 0 1 1 1 0 F-box domain DUF5565 PF17720.1 CDO72983.1 - 0.1 11.4 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5565) HTH_15 PF12324.8 CDO72983.1 - 0.16 12.0 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase LRR_6 PF13516.6 CDO72983.1 - 1.1 9.5 3.1 7.4 6.9 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 CDO72983.1 - 4.5 7.8 8.4 12 6.4 0.0 4.7 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) TatD_DNase PF01026.21 CDO72984.1 - 4.6e-39 134.3 0.0 6.5e-38 130.6 0.0 2.0 1 1 0 1 1 1 1 TatD related DNase Hydrolase PF00702.26 CDO72984.1 - 0.02 15.2 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nif11 PF07862.11 CDO72984.1 - 0.029 14.7 0.2 2.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Nif11 domain Amidohydro_2 PF04909.14 CDO72984.1 - 0.052 13.3 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Amidohydrolase Radical_SAM PF04055.21 CDO72984.1 - 0.15 12.4 0.0 0.48 10.8 0.0 1.7 2 0 0 2 2 2 0 Radical SAM superfamily Thiolase_N PF00108.23 CDO72985.1 - 6e-71 238.9 0.2 8.2e-71 238.4 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDO72985.1 - 6e-08 32.4 0.0 1.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CDO72985.1 - 0.0024 17.5 0.8 0.022 14.4 0.0 2.8 2 1 2 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CDO72985.1 - 0.038 13.8 0.0 7.7 6.4 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Hepar_II_III PF07940.13 CDO72986.1 - 2.5e-08 33.8 0.6 4.4e-08 33.0 0.6 1.3 1 0 0 1 1 1 1 Heparinase II/III-like protein SOG2 PF10428.9 CDO72987.1 - 5.4 6.1 26.3 8.6 5.4 26.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein PAP1 PF08601.10 CDO72987.1 - 6.5 6.4 26.6 13 5.4 26.6 1.5 1 0 0 1 1 1 0 Transcription factor PAP1 RIFIN PF02009.16 CDO72987.1 - 7.1 6.4 9.6 10 5.9 9.6 1.1 1 0 0 1 1 1 0 Rifin SMYLE_N PF18615.1 CDO72987.1 - 7.4 6.0 9.3 10 5.5 9.3 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain RsgA_GTPase PF03193.16 CDO72988.1 - 0.21 11.5 0.0 0.28 11.1 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Methyltransf_23 PF13489.6 CDO72989.1 - 0.00081 19.3 0.0 0.0029 17.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO72989.1 - 0.033 14.9 0.0 0.31 11.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain NAD_binding_4 PF07993.12 CDO72989.1 - 0.19 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein ThrE PF06738.12 CDO72990.1 - 8.3e-50 169.4 7.8 8.3e-50 169.4 7.8 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CDO72990.1 - 5.8e-07 29.7 9.5 5.8e-07 29.7 9.5 2.5 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE SNF2_N PF00176.23 CDO72991.1 - 6.5e-70 235.6 0.0 9.6e-70 235.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDO72991.1 - 1.5e-14 54.3 0.0 1.8e-13 50.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 CDO72991.1 - 8.6e-05 22.4 3.1 0.0002 21.2 3.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 CDO72991.1 - 0.033 14.2 0.1 1.6 8.7 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CDO72991.1 - 0.083 12.8 3.9 0.22 11.4 3.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDO72991.1 - 0.14 12.0 1.3 0.43 10.5 1.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO72991.1 - 0.19 11.8 3.2 0.55 10.3 3.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 CDO72991.1 - 0.42 10.5 4.0 0.93 9.4 4.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CDO72991.1 - 4.5 7.7 7.0 2.5 8.5 0.3 2.6 2 0 0 2 2 2 0 Ring finger domain Glyco_hydro_20b PF02838.15 CDO72992.1 - 9.9e-11 42.5 0.2 3.3e-10 40.8 0.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 CDO72992.1 - 3.2e-09 36.6 0.0 9.9e-09 35.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain PDZ PF00595.24 CDO72992.1 - 0.083 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 PDZ domain dsrm PF00035.26 CDO72993.1 - 1e-08 35.7 0.1 2.3e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 CDO72993.1 - 0.0075 16.4 0.0 0.017 15.3 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like AcetDehyd-dimer PF09290.11 CDO72993.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation SNF2_N PF00176.23 CDO72994.1 - 2.2e-60 204.2 0.2 3.6e-60 203.5 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.8 CDO72994.1 - 2.4e-21 76.2 0.7 5.6e-21 75.0 0.7 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.31 CDO72994.1 - 2.4e-20 72.9 0.0 1.3e-19 70.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.6 CDO72994.1 - 5.7e-11 42.3 7.1 2.6e-08 33.6 0.4 3.5 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain ResIII PF04851.15 CDO72994.1 - 8.2e-09 35.7 0.2 2.2e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.24 CDO72994.1 - 0.00022 21.1 1.1 0.093 12.7 0.0 3.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ERCC3_RAD25_C PF16203.5 CDO72994.1 - 0.001 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Glycos_transf_2 PF00535.26 CDO72994.1 - 0.12 12.2 0.1 19 5.1 0.0 3.4 4 0 0 4 4 4 0 Glycosyl transferase family 2 PHD PF00628.29 CDO72994.1 - 1 9.3 8.4 6.8 6.7 0.1 3.8 4 0 0 4 4 4 0 PHD-finger Cytochrome_C7 PF14522.6 CDO72994.1 - 3.6 7.6 5.0 3.1 7.8 0.9 2.8 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Sec8_exocyst PF04048.14 CDO72995.1 - 1e-35 122.7 1.2 2.5e-35 121.4 1.2 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 CDO72995.1 - 7.2e-09 35.3 1.4 1.4e-08 34.4 1.4 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 CDO72995.1 - 0.00012 21.9 0.2 0.00064 19.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) FIVAR PF07554.13 CDO72995.1 - 0.021 15.6 0.1 0.049 14.4 0.1 1.6 1 0 0 1 1 1 0 FIVAR domain Atg14 PF10186.9 CDO72995.1 - 0.11 11.6 0.8 0.24 10.4 0.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IZUMO PF15005.6 CDO72995.1 - 0.18 12.3 0.9 5.8 7.4 0.7 3.2 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Complex1_LYR PF05347.15 CDO72996.1 - 0.017 15.1 0.7 0.033 14.2 0.7 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Cellulase PF00150.18 CDO72997.1 - 2.1e-40 138.9 0.0 2.8e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 CDO72997.1 - 3.9e-12 45.9 9.9 9.8e-12 44.6 9.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Kelch_4 PF13418.6 CDO72998.1 - 8.5e-26 89.7 26.4 5.7e-08 32.6 1.2 6.7 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 CDO72998.1 - 9.5e-25 85.9 20.6 7.9e-09 35.0 0.2 5.2 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 CDO72998.1 - 3.3e-24 84.4 12.6 6.9e-06 25.9 0.1 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 CDO72998.1 - 1.8e-23 82.0 17.8 3.1e-08 33.6 0.5 6.8 6 1 1 7 7 7 4 Kelch motif Kelch_3 PF13415.6 CDO72998.1 - 9.1e-20 70.5 24.6 0.00067 19.9 0.3 7.2 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 CDO72998.1 - 3.9e-14 52.0 17.8 0.0012 18.8 0.6 6.4 6 1 0 6 6 6 4 Kelch motif PQQ_3 PF13570.6 CDO72998.1 - 2.6 8.6 15.8 20 5.8 0.2 5.5 5 1 1 6 6 6 0 PQQ-like domain Esterase PF00756.20 CDO72999.1 - 8.4e-39 133.7 0.0 2.8e-37 128.7 0.0 2.1 2 0 0 2 2 2 1 Putative esterase PGAP1 PF07819.13 CDO72999.1 - 8.4e-09 35.5 0.1 7.4e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 CDO72999.1 - 5.2e-05 23.0 0.1 0.0049 16.5 0.1 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO72999.1 - 6.6e-05 22.3 0.0 0.027 13.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Palm_thioest PF02089.15 CDO72999.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 CDO72999.1 - 0.0018 17.6 0.0 0.054 12.8 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 CDO72999.1 - 0.0023 18.6 10.6 0.0032 18.1 0.2 3.0 3 1 0 3 3 2 2 Alpha/beta hydrolase family DUF676 PF05057.14 CDO72999.1 - 0.022 14.3 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CDO72999.1 - 0.044 13.7 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Lipase (class 3) Thioesterase PF00975.20 CDO72999.1 - 0.093 12.8 0.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain LCAT PF02450.15 CDO72999.1 - 0.17 11.0 0.0 0.93 8.6 0.0 1.9 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase MMR_HSR1 PF01926.23 CDO73000.1 - 9.8e-16 57.9 0.1 5.4e-15 55.5 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDO73000.1 - 2.3e-07 30.9 0.0 0.00092 19.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CDO73000.1 - 2e-05 24.2 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 CDO73000.1 - 0.006 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CDO73000.1 - 0.016 15.3 0.1 0.047 13.8 0.1 1.8 1 0 0 1 1 1 0 Dynamin family AIM3 PF17096.5 CDO73000.1 - 9.7 7.2 10.1 10 7.1 0.1 3.4 3 0 0 3 3 3 0 Altered inheritance of mitochondria protein 3 EF_TS PF00889.19 CDO73001.1 - 2.6e-14 53.3 0.0 5.8e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor TS UBA_4 PF14555.6 CDO73001.1 - 0.00041 20.1 0.1 0.00072 19.3 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.31 CDO73001.1 - 0.0051 16.7 0.3 0.011 15.6 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Taxilin PF09728.9 CDO73002.1 - 1.5e-16 60.5 36.7 1.9e-10 40.4 20.5 3.0 2 1 1 3 3 3 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.8 CDO73002.1 - 1e-07 31.6 0.5 0.007 16.2 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDO73002.1 - 0.00056 19.6 0.1 0.057 13.2 0.0 2.9 2 0 0 2 2 2 1 Ubiquitin family PriA_C PF18074.1 CDO73002.1 - 0.012 16.4 2.5 0.12 13.2 2.5 2.7 1 1 0 1 1 1 0 Primosomal protein N C-terminal domain YukD PF08817.10 CDO73002.1 - 0.033 14.9 0.0 0.082 13.6 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PARM PF17061.5 CDO73002.1 - 0.033 14.3 0.2 0.033 14.3 0.2 2.3 2 1 0 2 2 2 0 PARM DUF2935 PF11155.8 CDO73002.1 - 0.16 12.3 7.8 0.033 14.5 3.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF3450 PF11932.8 CDO73002.1 - 0.29 10.4 14.0 1.6 8.0 10.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TMEM237 PF15383.6 CDO73002.1 - 1.2 8.1 2.8 2.6 7.1 2.8 1.5 1 0 0 1 1 1 0 Transmembrane protein 237 DUF1664 PF07889.12 CDO73002.1 - 2.4 8.2 8.8 2.9 7.9 7.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Prominin PF05478.11 CDO73002.1 - 3.2 5.6 9.0 4.6 5.1 9.0 1.1 1 0 0 1 1 1 0 Prominin LMBR1 PF04791.16 CDO73002.1 - 9.7 5.0 11.7 16 4.2 11.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein UDPGP PF01704.18 CDO73003.1 - 2.1e-45 155.2 0.0 2.6e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CDO73003.1 - 0.025 14.9 0.0 0.075 13.4 0.0 1.9 2 0 0 2 2 2 0 MobA-like NTP transferase domain Lum_binding PF00677.17 CDO73005.1 - 3.1e-44 148.9 0.1 3.4e-21 75.0 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain SspH PF08141.12 CDO73005.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Small acid-soluble spore protein H family DUF148 PF02520.17 CDO73006.1 - 0.31 11.2 1.5 0.51 10.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 Myosin_head PF00063.21 CDO73007.1 - 9.1e-240 797.5 0.2 1.1e-239 797.2 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CDO73007.1 - 3.7e-56 189.8 0.0 7.4e-56 188.8 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 CDO73007.1 - 7.8e-11 41.7 0.3 2e-10 40.4 0.3 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDO73007.1 - 1.3e-09 37.5 0.9 2.7e-09 36.5 0.9 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDO73007.1 - 2.6e-09 36.6 0.0 9e-09 34.9 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CDO73007.1 - 4.9e-05 23.5 1.5 9.8e-05 22.6 0.6 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.13 CDO73007.1 - 0.0092 15.8 0.2 0.024 14.5 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_16 PF13191.6 CDO73007.1 - 0.038 14.4 0.0 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CDO73007.1 - 0.069 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 CDO73007.1 - 0.069 12.7 1.0 8.2 5.9 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 CDO73007.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain UNC45-central PF11701.8 CDO73008.1 - 5.5e-30 104.4 0.1 2e-29 102.5 0.1 2.0 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central U3snoRNP10 PF12397.8 CDO73008.1 - 0.00085 19.7 0.4 0.33 11.3 0.1 3.4 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 DUF2950 PF11453.8 CDO73008.1 - 0.21 10.8 0.2 0.52 9.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2950) HEAT PF02985.22 CDO73008.1 - 3.4 8.2 9.1 55 4.4 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat Gcd10p PF04189.13 CDO73009.1 - 3.1e-67 226.8 0.0 5.5e-67 226.0 0.0 1.3 1 1 0 1 1 1 1 Gcd10p family GIDA_assoc PF13932.6 CDO73009.1 - 0.089 13.0 1.3 0.15 12.2 1.3 1.3 1 0 0 1 1 1 0 GidA associated domain p450 PF00067.22 CDO73010.1 - 6.6e-54 183.4 0.0 1e-53 182.8 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Ceramidase PF05875.12 CDO73011.1 - 8.1e-76 254.9 10.7 9.1e-76 254.8 10.7 1.0 1 0 0 1 1 1 1 Ceramidase BRCA-2_OB1 PF09103.10 CDO73012.1 - 7.2e-36 122.8 0.0 1.4e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 CDO73012.1 - 6.6e-06 25.9 0.3 0.00012 21.8 0.2 2.2 2 0 0 2 2 2 1 BRCA2, helical Rb_C PF08934.10 CDO73012.1 - 0.032 14.0 0.3 0.07 12.9 0.3 1.5 1 0 0 1 1 1 0 Rb C-terminal domain TPR_14 PF13428.6 CDO73013.1 - 0.12 13.2 0.5 11 7.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M16 PF00675.20 CDO73014.1 - 2.6e-39 134.6 0.0 5.5e-39 133.5 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDO73014.1 - 7.6e-33 114.1 0.0 1.6e-32 113.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase M16 inactive domain Transposase_21 PF02992.14 CDO73015.1 - 1.8e-27 96.0 0.3 1.3e-26 93.1 0.0 2.3 2 1 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 CDO73015.1 - 4.7e-05 23.0 0.0 0.00013 21.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Fmp27_WPPW PF10359.9 CDO73016.1 - 0.018 13.9 0.1 0.023 13.5 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Herpes_UL25 PF01499.16 CDO73016.1 - 0.33 9.4 6.1 0.39 9.2 6.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Atg14 PF10186.9 CDO73016.1 - 0.42 9.7 4.6 0.58 9.2 4.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MscS_TM PF12794.7 CDO73016.1 - 0.87 8.4 9.1 1.2 8.0 9.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4407 PF14362.6 CDO73016.1 - 0.87 8.9 15.1 1.1 8.5 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CDO73016.1 - 2.3 7.0 10.1 3 6.7 10.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 CDO73016.1 - 7.9 3.8 16.1 9.5 3.6 16.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FPN1 PF06963.12 CDO73018.1 - 1.2e-76 258.1 3.1 1.3e-76 257.9 3.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) CreD PF06123.12 CDO73018.1 - 0.013 14.3 0.6 0.022 13.6 0.6 1.2 1 0 0 1 1 1 0 Inner membrane protein CreD Wzy_C_2 PF11846.8 CDO73018.1 - 0.071 13.0 1.4 0.28 11.1 0.1 2.2 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal PXA PF02194.15 CDO73019.1 - 3.5e-33 115.1 1.4 9.9e-32 110.4 0.1 3.4 1 1 1 2 2 2 1 PXA domain Nexin_C PF08628.12 CDO73019.1 - 8e-29 100.5 0.2 7.4e-28 97.4 0.0 2.8 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 CDO73019.1 - 1.6e-18 66.7 0.0 1.1e-17 64.0 0.0 2.4 2 0 0 2 2 2 1 PX domain RGS PF00615.19 CDO73019.1 - 2.3e-10 40.8 0.1 1.7e-09 38.0 0.1 2.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain Isy1 PF06246.12 CDO73019.1 - 0.012 15.2 0.1 0.012 15.2 0.1 2.3 2 1 0 2 2 2 0 Isy1-like splicing family ABC_tran_CTD PF16326.5 CDO73019.1 - 0.015 15.5 8.6 0.12 12.6 3.8 2.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain Peptidase_C54 PF03416.19 CDO73019.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C54 ParB PF08775.10 CDO73019.1 - 0.3 11.6 3.2 2.5 8.6 0.1 2.9 2 0 0 2 2 2 0 ParB family Mito_carr PF00153.27 CDO73020.1 - 1.5e-20 72.9 0.2 4.2e-10 39.4 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Glyco_hydro_7 PF00840.20 CDO73021.1 - 4.5e-215 714.4 16.8 5.1e-215 714.2 16.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Filament PF00038.21 CDO73022.1 - 0.0023 17.6 36.8 0.0023 17.6 36.8 10.9 1 1 8 10 10 10 4 Intermediate filament protein Laminin_II PF06009.12 CDO73022.1 - 0.011 15.7 1.3 0.011 15.7 1.3 12.6 4 3 8 14 14 14 0 Laminin Domain II BST2 PF16716.5 CDO73022.1 - 0.012 16.1 5.1 0.012 16.1 5.1 16.1 7 5 8 16 16 16 0 Bone marrow stromal antigen 2 Fez1 PF06818.15 CDO73022.1 - 0.2 12.1 203.4 0.22 11.9 16.1 11.4 2 2 8 10 10 10 0 Fez1 DAO PF01266.24 CDO73023.1 - 7.9e-29 101.3 0.0 8.8e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDO73023.1 - 0.0079 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CDO73023.1 - 0.015 15.8 0.0 0.04 14.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO73023.1 - 0.018 15.2 0.1 0.043 14.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 CDO73023.1 - 0.033 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 CDO73023.1 - 0.035 14.3 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CDO73023.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 CDO73023.1 - 0.11 11.7 0.0 1.9 7.6 0.1 2.3 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 CDO73023.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 CDO73023.1 - 0.16 11.4 0.0 0.47 9.9 0.0 1.7 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Transposase_21 PF02992.14 CDO73026.1 - 3.4e-13 49.3 0.0 5.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 CDO73026.1 - 0.011 14.9 0.3 0.022 14.0 0.3 1.5 1 0 0 1 1 1 0 Plavaka transposase DUF4218 PF13960.6 CDO73026.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) NUC130_3NT PF08158.12 CDO73026.1 - 3.3 8.1 4.4 2.9 8.3 0.3 2.6 3 0 0 3 3 3 0 NUC130/3NT domain Iwr1 PF08574.10 CDO73026.1 - 6.3 7.9 8.5 8.3 7.5 7.1 1.9 1 1 0 1 1 1 0 Transcription factor Iwr1 AF-4 PF05110.13 CDO73027.1 - 0.28 9.2 11.0 0.44 8.6 11.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein BTB PF00651.31 CDO73029.1 - 0.026 14.8 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain DNA_pol_viral_C PF00336.18 CDO73030.1 - 0.11 11.9 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain DUF1932 PF09130.11 CDO73031.1 - 0.046 13.7 0.1 0.41 10.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) UPF0242 PF06785.11 CDO73031.1 - 0.098 12.8 0.9 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 CDO73031.1 - 7 7.2 7.6 17 5.9 0.5 2.8 3 0 0 3 3 3 0 Cell division protein ZapB Transposase_21 PF02992.14 CDO73032.1 - 6.2e-08 32.1 0.0 1.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 CDO73032.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF1258 PF06869.12 CDO73032.1 - 0.036 13.6 0.5 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) Fumble PF03630.14 CDO73033.1 - 3.4e-124 414.3 0.0 4.8e-124 413.8 0.0 1.2 1 0 0 1 1 1 1 Fumble Homeodomain PF00046.29 CDO73034.1 - 2e-47 158.9 17.1 3.5e-16 58.8 1.0 3.5 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 CDO73034.1 - 1.6e-15 56.7 1.1 0.0014 18.5 0.0 3.9 3 0 0 3 3 3 3 Homeobox KN domain HOCHOB PF17943.1 CDO73034.1 - 2.6e-10 41.0 0.0 0.049 14.4 0.0 3.2 3 0 0 3 3 3 3 Homeobox-cysteine loop-homeobox YdaS_antitoxin PF15943.5 CDO73034.1 - 1e-05 25.3 0.1 0.058 13.3 0.0 3.3 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homez PF11569.8 CDO73034.1 - 0.00067 19.1 2.1 2.8 7.5 0.0 3.8 4 0 0 4 4 4 2 Homeodomain leucine-zipper encoding, Homez HTH_3 PF01381.22 CDO73034.1 - 0.0007 19.6 0.2 6.1 7.0 0.0 3.7 3 0 0 3 3 3 1 Helix-turn-helix HTH_36 PF13730.6 CDO73034.1 - 0.041 13.8 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1510 PF07423.11 CDO73034.1 - 0.66 10.2 2.3 6.6 6.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1510) ADH_N PF08240.12 CDO73035.1 - 6.6e-26 90.3 2.9 1.2e-25 89.5 2.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO73035.1 - 1.9e-17 63.4 0.1 4.7e-16 59.0 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO73035.1 - 2.2e-06 28.8 0.0 4.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CDO73035.1 - 1.6e-05 24.3 0.5 2.6e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CDO73035.1 - 0.0004 19.8 0.3 0.00065 19.1 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Chitin_synth_1 PF01644.17 CDO73036.1 - 4.1e-72 241.5 0.2 6.4e-72 240.8 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 CDO73036.1 - 9.2e-25 87.2 0.8 2.4e-20 72.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 CDO73036.1 - 1.1e-24 86.1 0.0 3.2e-24 84.7 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 CDO73036.1 - 9.3e-07 28.9 0.2 9.3e-07 28.9 0.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Pkinase PF00069.25 CDO73037.1 - 3.7e-26 92.1 0.0 4.7e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73037.1 - 1.2e-13 51.0 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO73037.1 - 1.1e-09 37.6 0.0 1.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO73037.1 - 0.0017 18.3 1.2 0.0079 16.1 0.1 2.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CDO73037.1 - 0.017 14.5 0.7 0.11 11.8 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CDO73037.1 - 0.025 13.6 0.1 0.036 13.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Adaptin_N PF01602.20 CDO73038.1 - 4.5e-118 395.1 0.0 8.1e-118 394.2 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CDO73038.1 - 1.3e-56 191.0 1.0 2.7e-56 189.9 1.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CDO73038.1 - 4.6e-33 113.8 0.0 9.8e-33 112.7 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform cNMP_binding PF00027.29 CDO73038.1 - 6.6e-28 96.6 0.0 2.4e-15 56.3 0.0 5.6 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Patatin PF01734.22 CDO73038.1 - 2.1e-18 67.2 2.3 8.7e-13 48.9 1.3 2.9 2 0 0 2 2 2 2 Patatin-like phospholipase HEAT_2 PF13646.6 CDO73038.1 - 1.9e-16 60.2 1.9 7.7e-09 35.8 0.0 6.4 4 1 4 8 8 8 4 HEAT repeats Cnd1 PF12717.7 CDO73038.1 - 7.1e-07 29.4 7.7 0.15 12.1 0.0 5.2 6 0 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CDO73038.1 - 0.15 12.2 0.3 3 8.1 0.0 3.1 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 CDO73038.1 - 0.16 12.3 6.6 54 4.4 0.2 5.6 5 0 0 5 5 5 0 HEAT repeat Sec1 PF00995.23 CDO73039.1 - 5e-99 333.1 0.0 8.4e-98 329.1 0.0 1.9 1 1 1 2 2 2 2 Sec1 family SpoIIIAH PF12685.7 CDO73039.1 - 2.2 8.1 6.6 4.8 7.0 0.0 3.3 4 0 0 4 4 4 0 SpoIIIAH-like protein YABBY PF04690.13 CDO73040.1 - 9.4e-08 32.8 0.5 1e-07 32.7 0.5 1.1 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 CDO73040.1 - 0.0076 16.8 1.5 0.01 16.4 1.5 1.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 CDO73040.1 - 0.015 15.7 0.4 0.023 15.1 0.4 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box LRR_6 PF13516.6 CDO73041.1 - 0.00078 19.3 1.0 1.9 8.7 0.0 5.4 6 0 0 6 6 6 1 Leucine Rich repeat F-box-like PF12937.7 CDO73041.1 - 0.00095 19.0 1.3 0.0018 18.1 0.1 2.1 2 0 0 2 2 2 1 F-box-like Sas10_Utp3 PF04000.15 CDO73042.1 - 1.3e-17 64.2 0.1 3.8e-17 62.7 0.1 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family UPF0184 PF03670.13 CDO73042.1 - 0.07 13.5 0.9 0.48 10.8 0.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) HSBP1 PF06825.12 CDO73042.1 - 0.18 11.7 0.6 0.29 11.0 0.6 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 BHD_2 PF10404.9 CDO73042.1 - 0.38 11.7 0.3 0.38 11.7 0.3 3.1 3 1 0 3 3 3 0 Rad4 beta-hairpin domain 2 SF3b10 PF07189.11 CDO73043.1 - 2.6e-35 120.4 0.0 3.1e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Methyltransf_25 PF13649.6 CDO73044.1 - 6e-16 58.9 0.0 1.3e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO73044.1 - 2.6e-13 50.4 0.0 6.5e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO73044.1 - 1.5e-10 41.1 0.0 2.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDO73044.1 - 7.1e-09 35.3 0.0 1.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CDO73044.1 - 1.4e-08 35.4 0.0 3.8e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO73044.1 - 2.5e-07 30.6 0.0 4.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDO73044.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CDO73044.1 - 0.024 14.2 0.0 0.072 12.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_8 PF05148.15 CDO73044.1 - 0.11 12.3 0.0 6.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 CDO73044.1 - 0.12 11.0 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 CDO73044.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Mg_trans_NIPA PF05653.14 CDO73045.1 - 3.4e-73 246.3 16.4 1.9e-41 142.1 5.4 2.0 1 1 1 2 2 2 2 Magnesium transporter NIPA Cu-oxidase PF00394.22 CDO73046.1 - 1e-49 168.7 0.2 6.5e-48 162.8 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CDO73046.1 - 1.4e-39 134.8 1.1 2.9e-38 130.6 0.4 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CDO73046.1 - 9.7e-34 116.0 10.4 1e-32 112.7 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase WLM PF08325.10 CDO73047.1 - 5.1e-50 170.2 0.1 8e-50 169.6 0.1 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 CDO73047.1 - 9.7e-05 21.6 0.8 9.7e-05 21.6 0.8 3.1 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 CDO73047.1 - 0.0022 18.1 3.2 0.0059 16.7 3.2 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF45 zf-Sec23_Sec24 PF04810.15 CDO73047.1 - 0.025 14.6 5.9 17 5.6 0.7 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger SVIP PF15811.5 CDO73047.1 - 0.049 14.1 8.4 0.99 9.9 0.0 2.5 2 0 0 2 2 2 0 Small VCP/p97-interacting protein DZR PF12773.7 CDO73047.1 - 0.083 12.9 2.0 0.18 11.9 2.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-MIZ PF02891.20 CDO73047.1 - 0.19 11.5 4.0 10 6.0 0.0 3.1 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger zf-4CXXC_R1 PF10497.9 CDO73047.1 - 0.22 11.8 9.9 0.8 10.0 2.4 2.8 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 OrfB_Zn_ribbon PF07282.11 CDO73047.1 - 0.63 10.0 3.6 15 5.6 1.7 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain HalOD2 PF18547.1 CDO73047.1 - 5.5 7.0 11.0 2.8 7.9 0.7 3.5 2 1 1 3 3 3 0 Halobacterial output domain 2 C1_2 PF03107.16 CDO73047.1 - 8.6 6.8 6.8 37 4.7 5.4 2.3 1 1 1 2 2 2 0 C1 domain Bot1p PF12298.8 CDO73048.1 - 2.5e-24 86.4 0.0 4.2e-24 85.7 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Cpn60_TCP1 PF00118.24 CDO73049.1 - 8.9e-155 516.0 1.6 1.1e-154 515.8 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MFS_1 PF07690.16 CDO73049.1 - 4e-18 65.5 21.4 4e-18 65.5 21.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CDO73049.1 - 0.051 12.4 5.4 0.085 11.7 5.4 1.3 1 0 0 1 1 1 0 MFS_1 like family SNF2_N PF00176.23 CDO73050.1 - 1.7e-67 227.7 0.0 2.2e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 CDO73050.1 - 9e-18 64.0 0.0 2.6e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 CDO73050.1 - 6.5e-15 55.4 0.0 1.3e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO73050.1 - 1.2e-06 28.6 0.0 4.9e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CDO73050.1 - 1.6e-06 27.9 13.8 2.9e-06 27.0 13.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CDO73050.1 - 4.7e-06 26.5 0.0 9.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 CDO73050.1 - 6e-05 22.8 14.4 0.0003 20.6 14.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDO73050.1 - 0.0001 22.1 11.0 0.00017 21.4 11.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO73050.1 - 0.0001 22.2 10.7 0.00026 20.9 10.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDO73050.1 - 0.0011 19.3 12.9 0.002 18.4 12.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-MIZ PF02891.20 CDO73050.1 - 0.0053 16.5 7.6 0.0094 15.7 7.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.6 CDO73050.1 - 0.0094 16.1 14.1 0.018 15.2 14.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD_2 PF06733.15 CDO73050.1 - 0.032 13.9 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 zf-RING_5 PF14634.6 CDO73050.1 - 0.052 13.5 12.5 0.093 12.7 12.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.6 CDO73050.1 - 0.15 12.0 5.3 0.41 10.5 5.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Patched PF02460.18 CDO73050.1 - 0.18 9.9 0.0 0.26 9.3 0.0 1.1 1 0 0 1 1 1 0 Patched family zf-Nse PF11789.8 CDO73050.1 - 0.68 9.8 6.6 1.7 8.5 6.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_clus PF00172.18 CDO73051.1 - 2.3e-07 30.8 5.8 3.3e-07 30.3 5.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HLH PF00010.26 CDO73052.1 - 2.3e-06 27.5 0.0 5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ndc1_Nup PF09531.10 CDO73052.1 - 2.3 6.8 6.6 2.6 6.6 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cu-oxidase PF00394.22 CDO73053.1 - 3.1e-46 157.4 0.2 9.9e-45 152.5 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CDO73053.1 - 1.3e-40 138.3 4.7 1.1e-35 122.4 0.1 3.7 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 CDO73053.1 - 2.1e-37 127.8 0.3 8.2e-36 122.6 0.2 2.6 2 0 0 2 2 2 1 Multicopper oxidase Glyco_hydro_3_C PF01915.22 CDO73054.1 - 7.7e-45 153.4 0.0 1.1e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CDO73054.1 - 1.5e-29 103.4 0.0 2.7e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CDO73054.1 - 4.5e-07 29.9 0.0 9.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain BSP PF04450.12 CDO73055.1 - 1.9e-35 122.5 0.0 4.2e-25 88.8 0.0 2.4 2 1 0 2 2 2 2 Peptidase of plants and bacteria SprT-like PF10263.9 CDO73055.1 - 0.072 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 SprT-like family NIF PF03031.18 CDO73056.1 - 5.2e-06 26.3 0.2 0.0091 15.8 0.0 2.7 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 CDO73056.1 - 0.0003 20.7 0.0 0.002 18.0 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 CDO73056.1 - 0.0014 19.0 0.0 0.003 17.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain KCT2 PF17818.1 CDO73056.1 - 2.7 8.1 11.7 0.21 11.7 1.7 2.4 2 0 0 2 2 2 0 Keratinocyte-associated gene product adh_short PF00106.25 CDO73057.1 - 6.1e-47 159.6 0.1 7.8e-47 159.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO73057.1 - 1.5e-31 109.8 0.0 1.9e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 CDO73057.1 - 5.9e-06 25.9 0.0 0.00017 21.1 0.0 2.3 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 CDO73057.1 - 9.4e-05 22.4 0.2 0.00026 21.0 0.2 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO73057.1 - 0.00026 20.5 0.2 0.00043 19.8 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CDO73057.1 - 0.00041 20.3 0.1 0.00065 19.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DFP PF04127.15 CDO73057.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Proho_convert PF12177.8 CDO73057.1 - 0.16 12.0 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Prohormone convertase enzyme RmlD_sub_bind PF04321.17 CDO73057.1 - 0.2 10.7 0.0 0.38 9.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain APH PF01636.23 CDO73059.1 - 5.1e-17 62.6 0.2 8.1e-17 61.9 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO73059.1 - 3.2e-05 23.6 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 CDO73059.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 CDO73059.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 CDO73059.1 - 0.18 11.4 0.0 1.1 8.8 0.0 1.9 2 0 0 2 2 2 0 RIO1 family adh_short PF00106.25 CDO73060.1 - 4.2e-50 169.9 1.7 5.7e-50 169.5 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO73060.1 - 3.2e-35 121.8 0.3 4.4e-35 121.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 CDO73060.1 - 1.7e-11 44.0 0.0 5.2e-11 42.5 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 CDO73060.1 - 8.6e-07 28.6 0.2 2.5e-06 27.1 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CDO73060.1 - 1.2e-05 25.3 0.5 3.7e-05 23.7 0.5 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDO73060.1 - 3.2e-05 23.9 0.1 7.7e-05 22.7 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CDO73060.1 - 0.0086 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CDO73060.1 - 0.025 14.0 0.0 0.068 12.6 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 CDO73060.1 - 0.056 13.3 0.2 0.099 12.5 0.2 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_3 PF03447.16 CDO73060.1 - 0.13 12.9 0.2 1.3 9.7 0.0 2.2 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain EF-hand_6 PF13405.6 CDO73061.1 - 5.6e-12 44.6 1.3 2.1e-06 27.2 0.2 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDO73061.1 - 5.2e-09 35.0 2.7 1.3e-05 24.4 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CDO73061.1 - 2.6e-07 31.0 1.3 0.00055 20.3 0.0 3.1 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CDO73061.1 - 0.001 18.5 1.1 0.0031 16.9 0.2 2.1 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CDO73061.1 - 0.037 14.3 0.0 5 7.5 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 CDO73061.1 - 0.18 11.7 0.9 1.7 8.6 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair SOBP PF15279.6 CDO73062.1 - 3.1 8.3 8.7 4.8 7.7 8.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein NPR3 PF03666.13 CDO73062.1 - 5.3 5.7 7.8 7.1 5.3 7.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-C2H2 PF00096.26 CDO73064.1 - 1.8e-08 34.4 19.0 9e-05 22.7 1.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO73064.1 - 0.0028 18.3 1.3 0.0028 18.3 1.3 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 CDO73064.1 - 0.0032 18.1 0.8 0.0032 18.1 0.8 3.5 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CDO73064.1 - 0.0034 17.6 0.3 0.0034 17.6 0.3 3.2 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CDO73064.1 - 0.0067 16.8 4.2 0.0067 16.8 4.2 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-met PF12874.7 CDO73064.1 - 0.017 15.5 0.3 0.017 15.5 0.3 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zap1_zf2 PF18217.1 CDO73064.1 - 1 9.4 13.9 0.71 9.9 3.2 2.4 2 0 0 2 2 2 0 Zap1 zinc finger 2 DUF3591 PF12157.8 CDO73065.1 - 6.5e-190 631.5 0.7 9.9e-190 630.9 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) TFIIF_beta PF02270.15 CDO73065.1 - 0.00089 19.3 0.2 0.0019 18.3 0.2 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain BCA_ABC_TP_C PF12399.8 CDO73065.1 - 0.15 12.0 0.2 0.38 10.7 0.2 1.7 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter NifT PF06988.11 CDO73065.1 - 0.32 10.8 1.8 1.2 9.0 0.1 2.6 2 0 0 2 2 2 0 NifT/FixU protein PA28_beta PF02252.18 CDO73066.1 - 2.5e-38 131.0 4.3 1.2e-36 125.6 4.3 2.2 1 1 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 CDO73066.1 - 2.9e-06 27.2 0.1 6.2e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit WD40 PF00400.32 CDO73067.1 - 6.9e-13 48.9 12.5 0.00058 20.6 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.11 CDO73067.1 - 8.5e-05 22.5 0.3 0.0011 18.8 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A CAF1C_H4-bd PF12265.8 CDO73067.1 - 0.00073 19.7 0.0 0.0023 18.2 0.0 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF1770 PF08589.10 CDO73067.1 - 3.7 8.6 9.0 12 6.9 1.5 2.8 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1770) MAPEG PF01124.18 CDO73068.1 - 3.8e-22 78.6 0.4 4.5e-22 78.3 0.4 1.1 1 0 0 1 1 1 1 MAPEG family CENP-U PF13097.6 CDO73069.1 - 0.52 10.3 6.7 0.42 10.6 5.4 1.5 1 1 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Transthyretin PF00576.21 CDO73070.1 - 5.8e-35 120.3 0.0 6.7e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family RabGAP-TBC PF00566.18 CDO73072.1 - 2.6e-28 99.2 0.0 3.5e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nop52 PF05997.12 CDO73074.1 - 7.8e-75 251.4 0.0 1.1e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 CDO73074.1 - 8.1e-06 25.6 0.0 2.2e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II TAN PF11640.8 CDO73074.1 - 0.035 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair GCP_N_terminal PF17681.1 CDO73075.1 - 9.4e-26 91.1 0.1 6.2e-24 85.2 0.1 2.5 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CDO73075.1 - 1.7e-25 90.2 0.0 3.6e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal HMGL-like PF00682.19 CDO73076.1 - 1.2e-80 270.8 0.2 1.9e-80 270.3 0.2 1.3 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 CDO73076.1 - 0.041 14.4 0.1 0.083 13.4 0.1 1.4 1 0 0 1 1 1 0 FliG N-terminal domain Pyrophosphatase PF00719.19 CDO73077.1 - 3.3e-60 202.5 0.2 4.3e-60 202.1 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase I-set PF07679.16 CDO73078.1 - 0.024 14.7 0.1 1.2 9.2 0.0 3.5 5 0 0 5 5 5 0 Immunoglobulin I-set domain GalKase_gal_bdg PF10509.9 CDO73078.1 - 0.025 14.1 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 Galactokinase galactose-binding signature PBP1_TM PF14812.6 CDO73078.1 - 2.4 8.6 4.3 4.8 7.6 4.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AMP-binding PF00501.28 CDO73079.1 - 8.2e-36 123.5 0.0 2e-29 102.5 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 CDO73079.1 - 2e-12 47.2 0.2 4.5e-12 46.1 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CDO73079.1 - 1.4e-07 32.4 0.3 0.013 16.4 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 CDO73079.1 - 4.3e-07 29.4 7.1 0.036 13.8 0.0 6.5 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CDO73079.1 - 0.13 12.1 2.4 2.4 8.0 0.2 3.6 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase DUF4618 PF15397.6 CDO73079.1 - 0.47 9.8 2.8 0.74 9.2 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Thioredoxin PF00085.20 CDO73080.1 - 2.7e-25 88.3 0.0 3.5e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CDO73080.1 - 1.3e-07 32.0 0.2 4.6e-07 30.3 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CDO73080.1 - 2.2e-05 24.2 0.0 2.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDO73080.1 - 0.00016 22.0 0.0 0.022 15.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CDO73080.1 - 0.00046 20.1 0.1 0.00073 19.5 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 CDO73080.1 - 0.00067 19.1 0.0 0.00083 18.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CDO73080.1 - 0.015 15.5 0.3 0.038 14.2 0.3 1.7 1 1 0 1 1 1 0 Thioredoxin-like DUF2847 PF11009.8 CDO73080.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) TraF PF13728.6 CDO73080.1 - 0.028 14.2 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein CENP-T_C PF15511.6 CDO73081.1 - 4.8e-07 29.9 0.0 6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 CDO73081.1 - 7e-05 22.9 0.1 9.9e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CDO73081.1 - 0.00015 22.0 0.0 0.0002 21.7 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 CDO73081.1 - 0.0011 19.2 0.1 0.002 18.4 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDO73081.1 - 0.0021 18.4 0.2 0.0025 18.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CDO73081.1 - 0.066 13.3 0.0 0.077 13.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Kelch_4 PF13418.6 CDO73082.1 - 7.8e-17 61.0 0.0 4.3e-08 33.0 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CDO73082.1 - 2.5e-09 37.2 9.8 0.013 15.8 0.0 6.2 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CDO73082.1 - 8.2e-09 35.3 5.3 0.031 14.3 0.0 5.0 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 CDO73082.1 - 6.1e-05 23.1 1.2 0.21 11.9 0.0 4.0 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CDO73082.1 - 0.00012 21.9 0.1 1.8 8.7 0.0 3.9 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CDO73082.1 - 0.0002 20.9 0.0 0.0009 18.8 0.0 2.2 2 0 0 2 2 2 1 Kelch motif COesterase PF00135.28 CDO73084.1 - 1.2e-65 222.4 0.0 7.1e-57 193.4 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CDO73084.1 - 0.00033 20.6 0.1 0.00063 19.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Exo_endo_phos PF03372.23 CDO73085.1 - 3.5e-19 69.3 0.1 4.9e-19 68.8 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2244 PF10003.9 CDO73085.1 - 3.6 7.3 7.9 3.4 7.3 6.3 1.7 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF3099 PF11298.8 CDO73085.1 - 3.9 7.7 6.9 2.5 8.3 4.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Abhydrolase_3 PF07859.13 CDO73086.1 - 1.9e-49 168.4 0.0 3.1e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDO73086.1 - 1.3e-14 53.9 0.0 1.2e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 CDO73086.1 - 0.042 13.1 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 CDO73086.1 - 0.13 11.1 0.0 2 7.2 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_M24 PF00557.24 CDO73087.1 - 6.3e-39 133.8 0.0 7.9e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24 PF00557.24 CDO73088.1 - 5.2e-36 124.3 0.0 7.1e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Cnd2 PF05786.14 CDO73088.1 - 0.43 9.2 5.1 0.79 8.3 5.1 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 IMD PF08397.11 CDO73088.1 - 0.96 8.8 3.6 1.8 7.9 3.6 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain Coilin_N PF15862.5 CDO73088.1 - 1 9.2 4.3 3.1 7.6 4.2 1.8 2 0 0 2 2 2 0 Coilin N-terminus RibD_C PF01872.17 CDO73089.1 - 3.6e-28 98.8 0.0 2.1e-27 96.3 0.0 2.1 1 1 0 1 1 1 1 RibD C-terminal domain RhoGEF PF00621.20 CDO73090.1 - 1.3e-07 32.0 0.0 6.1e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain ZZ PF00569.17 CDO73092.1 - 2e-57 190.8 82.1 3.6e-12 45.9 9.1 6.3 6 0 0 6 6 6 6 Zinc finger, ZZ type N_BRCA1_IG PF16158.5 CDO73092.1 - 1.3e-30 106.1 0.0 3.1e-30 104.9 0.0 1.7 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene C1_2 PF03107.16 CDO73092.1 - 5.3e-15 55.5 64.8 0.00036 20.8 2.3 6.6 6 0 0 6 6 6 6 C1 domain FAD_binding_3 PF01494.19 CDO73093.1 - 4.4e-26 92.0 0.2 1.4e-25 90.3 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CDO73093.1 - 6.4e-07 29.5 2.4 1.6e-06 28.2 2.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDO73093.1 - 2.6e-05 23.6 1.4 3.9e-05 23.0 0.7 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDO73093.1 - 0.00044 20.0 5.7 0.0008 19.1 5.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CDO73093.1 - 0.00068 18.5 3.2 0.00095 18.0 3.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 CDO73093.1 - 0.00069 18.9 1.0 0.0013 18.1 1.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CDO73093.1 - 0.001 19.6 1.8 0.0022 18.5 1.8 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDO73093.1 - 0.0014 17.8 4.6 0.0026 16.9 4.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CDO73093.1 - 0.0028 17.0 1.1 0.0042 16.4 1.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CDO73093.1 - 0.0046 15.9 1.3 0.0071 15.2 1.3 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Amino_oxidase PF01593.24 CDO73093.1 - 0.0056 16.0 0.6 0.093 12.0 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 CDO73093.1 - 0.011 14.9 2.3 0.015 14.4 2.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.10 CDO73093.1 - 0.015 14.4 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 CDO73093.1 - 0.029 14.3 1.2 2.3 8.2 0.5 3.2 3 1 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CDO73093.1 - 0.18 10.8 0.8 0.45 9.5 0.8 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 CDO73093.1 - 0.2 11.5 1.2 0.4 10.5 1.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 CDO73093.1 - 0.33 10.3 5.3 0.57 9.5 5.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CDO73093.1 - 1.6 8.0 3.4 3.8 6.8 3.1 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Clostridium_P47 PF06597.11 CDO73094.1 - 2.9 6.5 8.9 3.3 6.3 8.9 1.0 1 0 0 1 1 1 0 Clostridium P-47 protein TMEM154 PF15102.6 CDO73094.1 - 4 7.3 6.1 4.8 7.1 6.1 1.1 1 0 0 1 1 1 0 TMEM154 protein family SseC PF04888.12 CDO73094.1 - 4.8 6.7 12.8 5.6 6.5 12.8 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family V-SNARE_C PF12352.8 CDO73095.1 - 5.5e-16 58.6 0.9 5.5e-16 58.6 0.9 2.7 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus VP4_helical PF17478.2 CDO73095.1 - 0.0023 17.5 0.1 0.99 8.8 0.0 2.1 2 0 0 2 2 2 2 Rotavirus VP4 helical domain LXG PF04740.12 CDO73095.1 - 0.0067 16.2 1.5 9.2 5.9 0.0 3.3 2 1 1 3 3 3 1 LXG domain of WXG superfamily CK2S PF15011.6 CDO73095.1 - 0.018 14.9 1.1 0.041 13.8 0.8 1.9 1 1 0 1 1 1 0 Casein Kinase 2 substrate Laminin_I PF06008.14 CDO73095.1 - 0.031 14.0 4.6 0.064 13.0 2.8 2.0 1 1 0 2 2 2 0 Laminin Domain I APG6_N PF17675.1 CDO73095.1 - 0.043 14.4 8.6 1.5 9.3 1.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TipAS PF07739.13 CDO73095.1 - 0.047 14.2 1.5 0.12 12.9 0.2 2.1 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Med30 PF11315.8 CDO73095.1 - 0.062 13.5 0.3 0.2 11.9 0.1 2.0 1 1 0 2 2 2 0 Mediator complex subunit 30 DUF4040 PF13244.6 CDO73095.1 - 0.081 13.1 0.4 0.13 12.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) DUF1664 PF07889.12 CDO73095.1 - 0.089 12.8 0.4 8.8 6.4 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 CDO73095.1 - 0.13 12.3 3.6 0.28 11.2 0.5 2.6 1 1 1 3 3 3 0 Laminin Domain II Occludin_ELL PF07303.13 CDO73095.1 - 0.14 12.9 0.5 3.6 8.4 0.2 2.7 2 1 1 3 3 3 0 Occludin homology domain Sec34 PF04136.15 CDO73095.1 - 0.21 11.5 2.5 0.56 10.1 0.3 2.3 2 1 1 3 3 3 0 Sec34-like family WXG100 PF06013.12 CDO73095.1 - 0.27 11.5 4.1 4 7.7 0.1 3.3 2 2 1 3 3 3 0 Proteins of 100 residues with WXG Atg14 PF10186.9 CDO73095.1 - 0.32 10.0 3.3 11 4.9 4.5 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 CDO73095.1 - 0.33 11.0 4.9 5.6 7.0 1.4 2.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 CDO73095.1 - 1.7 7.9 6.2 2.7 7.2 5.9 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein TatD_DNase PF01026.21 CDO73096.1 - 4.7e-22 78.6 0.0 8.3e-22 77.8 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase Met_10 PF02475.16 CDO73097.1 - 1.6e-47 161.9 0.0 2.8e-29 102.3 0.0 2.2 1 1 1 2 2 2 2 Met-10+ like-protein MethyltransfD12 PF02086.15 CDO73097.1 - 0.00025 20.8 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase tRNA_U5-meth_tr PF05958.11 CDO73097.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TRM PF02005.16 CDO73097.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Mito_carr PF00153.27 CDO73098.1 - 4.8e-44 148.2 0.2 2.6e-17 62.5 0.0 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CDO73098.1 - 3.2e-18 65.9 1.6 1.9e-06 28.2 0.0 4.8 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 CDO73098.1 - 1.1e-16 59.0 4.6 3.9e-05 22.9 0.2 6.0 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 CDO73098.1 - 1.5e-15 55.8 4.4 0.00012 21.7 0.2 5.6 6 0 0 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 CDO73098.1 - 1.6e-11 43.9 2.4 0.0026 17.6 0.0 4.8 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CDO73098.1 - 1e-08 34.3 4.7 0.00051 19.4 0.2 4.2 4 0 0 4 4 4 2 EF hand EcpB_C PF18649.1 CDO73099.1 - 0.084 12.8 0.2 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 EcpB C-terminal domain Amidase PF01425.21 CDO73100.1 - 1.5e-98 330.7 0.0 2.3e-98 330.1 0.0 1.3 1 0 0 1 1 1 1 Amidase DUF953 PF06110.11 CDO73100.1 - 7.4e-18 64.3 0.1 1.6e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) FR47 PF08445.10 CDO73101.1 - 3.4e-08 33.4 0.0 6.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CDO73101.1 - 8.1e-08 32.3 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO73101.1 - 1.2e-06 28.7 0.0 2.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO73101.1 - 7.5e-05 23.1 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDO73101.1 - 0.024 14.7 0.0 0.058 13.5 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CDO73101.1 - 0.031 14.9 0.0 0.06 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 CDO73101.1 - 0.17 11.9 0.2 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase MoaC PF01967.21 CDO73102.1 - 2.3e-45 154.0 0.2 6.7e-45 152.5 0.2 1.8 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 CDO73102.1 - 2.4e-37 127.7 0.0 4.1e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 CDO73102.1 - 5.6e-07 30.1 0.1 0.0012 19.3 0.0 2.3 1 1 1 2 2 2 2 Radical SAM superfamily NIPSNAP PF07978.13 CDO73104.1 - 3.9e-30 104.1 2.0 2.4e-23 82.3 0.3 2.2 2 0 0 2 2 2 2 NIPSNAP TPR_1 PF00515.28 CDO73104.1 - 0.19 11.6 1.0 0.37 10.7 1.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat T3SSipB PF16535.5 CDO73105.1 - 0.23 12.0 10.1 0.37 11.3 10.1 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB Macoilin PF09726.9 CDO73105.1 - 0.42 9.1 19.3 0.99 7.9 19.3 1.6 1 1 0 1 1 1 0 Macoilin family DUF3138 PF11336.8 CDO73105.1 - 0.56 8.8 1.7 0.74 8.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) LPP PF04728.13 CDO73105.1 - 1.2 9.6 7.1 1.2 9.5 5.2 2.1 1 1 0 1 1 1 0 Lipoprotein leucine-zipper WD40 PF00400.32 CDO73106.1 - 6.4e-58 191.4 23.8 1.3e-07 32.1 0.1 11.9 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.11 CDO73106.1 - 2.9e-47 160.1 0.0 4.6e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 CDO73106.1 - 4.6e-10 39.7 3.5 0.57 10.5 0.0 7.7 5 2 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDO73106.1 - 0.00017 21.0 0.0 0.00066 19.1 0.0 1.9 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 CDO73106.1 - 0.0007 18.4 6.0 7.9 5.0 0.2 5.3 4 2 2 6 6 6 3 Nucleoporin Nup120/160 Mcl1_mid PF12341.8 CDO73106.1 - 0.0063 15.9 0.2 0.21 10.9 0.0 2.7 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region DUF89 PF01937.19 CDO73107.1 - 3.8e-110 368.2 0.0 4.8e-110 367.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Ribonuclease_T2 PF00445.18 CDO73108.1 - 1.4e-40 139.5 0.0 2.1e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Aldedh PF00171.22 CDO73109.1 - 7.4e-111 370.9 0.0 1e-110 370.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-RING_2 PF13639.6 CDO73110.1 - 1.2e-10 41.6 7.7 2.3e-10 40.7 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDO73110.1 - 2.4e-09 37.3 8.1 5.1e-09 36.3 8.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDO73110.1 - 9.7e-07 28.5 9.4 9.7e-07 28.5 9.4 1.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO73110.1 - 1.6e-06 27.9 7.2 1.6e-06 27.9 7.2 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO73110.1 - 1.6e-06 28.0 7.9 4e-06 26.8 7.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CDO73110.1 - 3.1e-06 27.2 1.1 6.1e-06 26.2 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CDO73110.1 - 4.7e-05 23.2 4.8 4.7e-05 23.2 4.8 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 CDO73110.1 - 0.00017 21.3 6.5 0.00044 19.9 6.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CDO73110.1 - 0.0017 18.1 3.6 0.0017 18.1 3.6 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDO73110.1 - 0.017 14.9 6.2 0.034 14.0 6.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 CDO73110.1 - 0.26 11.6 0.1 0.26 11.6 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon Zn_ribbon_17 PF17120.5 CDO73110.1 - 0.43 10.2 4.6 0.99 9.1 4.6 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 CDO73110.1 - 0.58 10.3 4.2 1.8 8.7 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) FANCL_C PF11793.8 CDO73110.1 - 0.93 9.7 6.8 4.9 7.4 6.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 CDO73110.1 - 1.8 8.8 5.3 5.8 7.2 5.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 CDO73110.1 - 4.7 7.2 11.4 0.72 9.8 5.4 2.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.29 CDO73110.1 - 8.3 6.4 10.8 0.37 10.7 5.3 1.7 2 0 0 2 2 1 0 PHD-finger SnoaL_2 PF12680.7 CDO73111.1 - 0.001 19.7 0.0 0.003 18.2 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain DUF2358 PF10184.9 CDO73111.1 - 0.0022 18.3 0.0 0.0048 17.2 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL PF07366.12 CDO73111.1 - 0.017 14.9 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Lgl_C PF08596.10 CDO73112.1 - 1e-31 110.0 0.0 2.4e-31 108.8 0.0 1.6 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 CDO73112.1 - 3.2e-05 24.6 0.6 1.2 10.1 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO73112.1 - 0.00036 20.8 0.0 0.13 12.6 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Malate_DH PF12434.8 CDO73112.1 - 2 8.5 4.6 0.48 10.5 0.4 2.2 2 0 0 2 2 2 0 Malate dehydrogenase enzyme ICL PF00463.21 CDO73113.1 - 3.7e-193 642.8 0.0 4.2e-193 642.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CDO73113.1 - 1.8e-09 37.4 0.0 3.3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Na_H_Exchanger PF00999.21 CDO73116.1 - 2.4e-53 181.3 43.8 3.2e-53 180.9 43.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ECH_1 PF00378.20 CDO73118.1 - 7.2e-57 192.6 0.0 9.2e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDO73118.1 - 1.8e-29 103.3 0.0 6.3e-29 101.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF2431 PF10354.9 CDO73119.1 - 1.6e-21 77.3 0.0 2.8e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) GHL6 PF14871.6 CDO73119.1 - 0.072 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 WD40 PF00400.32 CDO73120.1 - 2.9e-17 62.7 4.4 2.7e-06 28.0 0.3 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CDO73120.1 - 5.4e-09 36.2 0.0 1.5e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ATP-synt_E PF05680.12 CDO73121.1 - 1.5e-18 66.9 0.2 1.8e-18 66.7 0.2 1.1 1 0 0 1 1 1 1 ATP synthase E chain Caudo_TAP PF02413.17 CDO73121.1 - 0.0085 16.2 0.0 0.0097 16.0 0.0 1.1 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK INO80_Ies4 PF08193.11 CDO73122.1 - 8e-05 22.7 0.2 8e-05 22.7 0.2 3.6 3 1 1 4 4 4 1 INO80 complex subunit Ies4 PBP1_TM PF14812.6 CDO73122.1 - 0.012 15.9 5.0 0.036 14.4 5.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.8 CDO73122.1 - 0.019 15.9 5.3 0.038 15.0 5.3 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.10 CDO73122.1 - 0.025 14.9 12.0 0.048 14.1 12.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 CDO73122.1 - 0.12 12.0 0.4 0.2 11.3 0.4 1.3 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 CDO73122.1 - 0.41 10.7 3.1 1.8 8.6 2.5 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 CDO73122.1 - 3.2 5.7 7.3 4.3 5.3 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi FYDLN_acid PF09538.10 CDO73122.1 - 6.2 7.6 12.2 2.2 9.0 8.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Dopey_N PF04118.14 CDO73123.1 - 1.6e-65 221.3 0.8 2.2e-64 217.5 0.0 2.7 3 0 0 3 3 3 1 Dopey, N-terminal HEAT_EZ PF13513.6 CDO73123.1 - 0.036 14.6 0.2 14 6.3 0.1 3.6 2 0 0 2 2 2 0 HEAT-like repeat Cohesin_HEAT PF12765.7 CDO73123.1 - 0.11 12.8 0.3 0.35 11.2 0.3 1.9 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion EF-hand_6 PF13405.6 CDO73124.1 - 3.7e-10 38.9 0.0 0.0015 18.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDO73124.1 - 2e-08 33.4 0.2 1.5e-05 24.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDO73124.1 - 2e-07 31.4 1.6 2.5e-07 31.0 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CDO73124.1 - 8.1e-07 28.2 0.2 4.3e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 CDO73124.1 - 0.00032 21.0 1.2 0.0041 17.4 0.1 2.5 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 CDO73124.1 - 0.067 13.1 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Spt46 PF17734.1 CDO73126.1 - 0.0046 16.8 0.2 0.0083 16.0 0.2 1.4 1 0 0 1 1 1 1 Spermatogenesis-associated protein 46 KDZ PF18758.1 CDO73127.1 - 3.4e-26 92.3 0.0 6.5e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 CDO73127.1 - 1.5e-14 54.4 0.1 2.9e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 CDO73128.1 - 3.7e-10 39.9 0.2 6.4e-10 39.1 0.2 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 CDO73128.1 - 3.9e-07 30.2 0.1 7.3e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC4 PF18717.1 CDO73128.1 - 0.011 15.6 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases ABC2_membrane PF01061.24 CDO73129.1 - 1.1e-66 224.2 53.4 3.8e-35 121.2 23.6 2.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CDO73129.1 - 1.1e-34 119.9 0.0 4.5e-16 59.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CDO73129.1 - 5.2e-23 80.8 0.0 3.9e-17 61.9 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CDO73129.1 - 5.6e-10 39.7 0.2 1.6e-09 38.2 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 CDO73129.1 - 3.4e-05 24.4 0.0 0.031 14.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CDO73129.1 - 0.00015 22.1 0.5 0.24 11.7 0.2 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CDO73129.1 - 0.001 19.5 0.0 0.14 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CDO73129.1 - 0.0014 18.8 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 CDO73129.1 - 0.0031 17.1 0.4 0.53 9.8 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 CDO73129.1 - 0.0035 17.2 0.0 0.62 9.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 CDO73129.1 - 0.0073 16.6 0.2 0.64 10.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDO73129.1 - 0.0083 15.8 0.1 0.059 13.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 CDO73129.1 - 0.014 15.8 2.0 1.1 9.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 CDO73129.1 - 0.017 14.9 0.0 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CDO73129.1 - 0.017 15.1 0.0 0.077 12.9 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 CDO73129.1 - 0.038 14.4 0.0 6.1 7.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 CDO73129.1 - 0.053 12.6 34.1 0.0072 15.5 13.2 2.6 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_25 PF13481.6 CDO73129.1 - 0.063 12.9 0.0 0.44 10.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 CDO73129.1 - 0.11 11.9 0.1 3.1 7.2 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 CDO73129.1 - 0.14 12.5 0.8 10 6.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CDO73129.1 - 0.18 11.5 0.0 9.6 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Prefoldin_2 PF01920.20 CDO73130.1 - 5.4e-19 68.1 11.5 6.6e-19 67.8 11.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Mei5 PF10376.9 CDO73130.1 - 0.0013 18.6 5.7 0.0017 18.2 5.7 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein Tropomyosin_1 PF12718.7 CDO73130.1 - 0.0069 16.6 1.8 0.0069 16.6 1.8 2.1 2 1 0 2 2 2 1 Tropomyosin like DHR10 PF18595.1 CDO73130.1 - 0.01 15.9 11.9 0.063 13.3 1.3 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Seryl_tRNA_N PF02403.22 CDO73130.1 - 0.021 15.1 9.8 0.05 13.8 9.6 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BPS1 PF05633.11 CDO73130.1 - 0.025 13.6 2.1 0.029 13.4 2.1 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related DUF3584 PF12128.8 CDO73130.1 - 0.04 11.4 6.9 0.054 11.0 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FliD_C PF07195.12 CDO73130.1 - 0.11 11.9 4.8 0.2 11.0 1.4 2.0 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus APG6_N PF17675.1 CDO73130.1 - 0.14 12.7 14.7 1.5 9.3 14.7 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region NCA2 PF08637.10 CDO73130.1 - 0.25 10.5 6.1 2.7 7.1 1.0 2.0 1 1 1 2 2 2 0 ATP synthase regulation protein NCA2 Herpes_UL14 PF03580.14 CDO73130.1 - 0.34 11.2 5.3 0.47 10.7 5.3 1.3 1 1 0 1 1 1 0 Herpesvirus UL14-like protein Prefoldin PF02996.17 CDO73130.1 - 0.85 9.5 15.5 0.45 10.4 4.6 2.6 2 1 1 3 3 3 0 Prefoldin subunit DUF5320 PF17253.2 CDO73130.1 - 1.1 10.4 4.1 0.6 11.2 0.8 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF148 PF02520.17 CDO73130.1 - 1.1 9.3 10.2 0.78 9.9 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 Coat_F PF07875.12 CDO73130.1 - 1.5 9.1 5.1 2.3 8.5 0.2 2.7 3 0 0 3 3 3 0 Coat F domain LMBR1 PF04791.16 CDO73130.1 - 1.7 7.4 3.2 2.1 7.1 3.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PRP1_N PF06424.12 CDO73130.1 - 2.4 8.6 6.2 3.5 8.0 6.2 1.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal DivIC PF04977.15 CDO73130.1 - 2.9 7.7 14.2 0.63 9.9 3.6 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 CDO73130.1 - 4.7 6.4 12.6 5.3 6.3 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF5595 PF18077.1 CDO73130.1 - 6.3 6.9 9.6 12 6.1 2.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) DUF4407 PF14362.6 CDO73130.1 - 7.1 5.9 8.3 28 4.0 8.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GTP_EFTU PF00009.27 CDO73131.1 - 2e-43 148.2 0.0 3.3e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CDO73131.1 - 5.5e-38 130.3 5.8 9e-38 129.6 5.8 1.3 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CDO73131.1 - 3.5e-24 84.9 0.0 8.6e-24 83.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CDO73131.1 - 2.5e-22 78.7 0.0 7.8e-22 77.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDO73131.1 - 3.3e-09 37.0 0.1 7.2e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDO73131.1 - 5.4e-05 23.2 0.1 0.00011 22.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CDO73131.1 - 0.026 14.0 0.1 0.07 12.6 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit EFG_II PF14492.6 CDO73131.1 - 0.073 13.2 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II Septin PF00735.18 CDO73131.1 - 0.13 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin Calreticulin PF00262.18 CDO73132.1 - 1.1e-161 537.8 10.3 1.4e-161 537.4 10.3 1.1 1 0 0 1 1 1 1 Calreticulin family OAD_gamma PF04277.13 CDO73132.1 - 0.37 11.4 3.4 0.46 11.1 0.1 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DSHCT PF08148.12 CDO73133.1 - 8e-54 181.7 0.7 1.9e-53 180.5 0.7 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 CDO73133.1 - 2.5e-33 116.2 0.0 3.9e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain Ski2_N PF17911.1 CDO73133.1 - 7.4e-32 110.0 0.0 1.4e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 CDO73133.1 - 3e-19 69.4 0.1 6.7e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDO73133.1 - 1.1e-06 28.8 0.0 2.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDO73133.1 - 1.5e-05 25.3 0.0 5.8e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF3516 PF12029.8 CDO73133.1 - 0.084 11.9 0.5 0.16 11.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) HTH_Tnp_ISL3 PF13542.6 CDO73133.1 - 0.13 11.7 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Ist1 PF03398.14 CDO73134.1 - 9.5e-08 32.1 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RasGEF PF00617.19 CDO73135.1 - 6.4e-39 134.0 0.1 1.1e-38 133.2 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CDO73135.1 - 3.3e-18 65.8 0.3 6.9e-18 64.8 0.3 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 CDO73135.1 - 1.6e-13 50.0 0.2 3.5e-13 48.9 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDO73135.1 - 4.4e-10 39.1 0.0 9.2e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CDO73135.1 - 5.4e-06 26.2 0.1 1.2e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ras PF00071.22 CDO73136.1 - 1.5e-56 190.4 0.2 1.8e-56 190.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO73136.1 - 4.1e-33 114.2 0.0 5.7e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO73136.1 - 4.2e-12 45.9 0.1 4.9e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CDO73136.1 - 3.4e-06 27.0 0.7 0.041 13.8 0.1 2.7 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 CDO73136.1 - 7.8e-06 25.4 0.0 9.4e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDO73136.1 - 1.2e-05 25.3 0.0 2.2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDO73136.1 - 9.8e-05 22.0 0.0 0.00018 21.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CDO73136.1 - 0.01 16.2 0.1 0.02 15.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 CDO73136.1 - 0.07 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin TniB PF05621.11 CDO73136.1 - 0.17 11.3 0.0 0.38 10.1 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein RRM_1 PF00076.22 CDO73137.1 - 2.1e-14 53.1 0.0 1.1e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDO73137.1 - 0.00026 20.6 0.0 0.93 9.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 CDO73139.1 - 1.3e-10 42.1 0.0 1.6e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDO73139.1 - 8.8e-07 29.3 0.0 1.2e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lactamase_B_3 PF13483.6 CDO73139.1 - 0.045 13.6 0.0 0.32 10.9 0.0 2.1 2 1 1 3 3 3 0 Beta-lactamase superfamily domain polyprenyl_synt PF00348.17 CDO73141.1 - 4.9e-64 215.8 0.0 5e-59 199.4 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase SIKE PF05769.11 CDO73145.1 - 1.4e-09 38.1 1.7 1.7e-09 37.9 1.7 1.1 1 0 0 1 1 1 1 SIKE family Cnn_1N PF07989.11 CDO73145.1 - 0.052 13.7 4.6 0.12 12.5 4.6 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 CDO73145.1 - 0.18 12.3 6.1 0.11 13.0 2.0 2.0 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 CDO73145.1 - 0.24 11.5 5.9 0.88 9.7 1.9 2.3 2 0 0 2 2 2 0 bZIP transcription factor Hpt PF01627.23 CDO73145.1 - 0.25 11.6 0.3 0.25 11.6 0.3 2.0 2 1 0 2 2 2 0 Hpt domain NYD-SP28_assoc PF14775.6 CDO73145.1 - 1 9.5 5.0 0.78 9.9 2.3 2.1 2 1 0 2 2 2 0 Sperm tail C-terminal domain YabA PF06156.13 CDO73145.1 - 1.3 9.7 6.1 1.1 10.0 3.0 1.9 1 1 1 2 2 2 0 Initiation control protein YabA NCBP3 PF10309.9 CDO73146.1 - 2e-08 34.0 0.1 3.2e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 CDO73146.1 - 0.0061 16.6 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 RNA binding domain RRM_3 PF08777.11 CDO73146.1 - 0.042 13.9 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif TPR_1 PF00515.28 CDO73147.1 - 1e-11 44.1 16.6 0.00011 21.9 2.3 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDO73147.1 - 1.2e-09 37.6 21.8 0.00063 19.7 2.7 5.9 5 1 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDO73147.1 - 1.1e-07 31.5 13.1 7.4e-06 25.6 2.9 4.4 4 1 1 5 5 5 2 TPR repeat TPR_17 PF13431.6 CDO73147.1 - 0.00012 22.3 12.1 0.053 13.9 1.2 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDO73147.1 - 0.00037 21.1 16.8 0.0012 19.5 7.4 4.0 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDO73147.1 - 0.0036 17.4 11.9 2.1 8.8 0.7 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO73147.1 - 0.0066 16.9 18.1 0.0095 16.4 2.7 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDO73147.1 - 0.008 16.9 14.6 0.077 13.8 4.7 5.3 3 1 2 5 5 4 2 Tetratricopeptide repeat ChAPs PF09295.10 CDO73147.1 - 0.017 14.1 0.7 0.028 13.4 0.7 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4439 PF14530.6 CDO73147.1 - 0.025 15.3 2.0 0.058 14.1 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) TPR_9 PF13371.6 CDO73147.1 - 0.56 10.4 4.7 0.54 10.4 1.9 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDO73147.1 - 0.82 9.6 5.0 20 5.2 2.7 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MMM1 PF10296.9 CDO73150.1 - 2.5e-05 23.5 0.0 7.9e-05 21.9 0.0 1.7 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 CDO73150.1 - 0.014 15.9 0.0 0.13 12.8 0.0 2.5 1 1 0 1 1 1 0 PH domain DUF4795 PF16043.5 CDO73152.1 - 4.4e-05 23.2 17.4 4.4e-05 23.2 17.4 5.6 1 1 4 6 6 6 1 Domain of unknown function (DUF4795) Spc7 PF08317.11 CDO73152.1 - 0.0018 17.2 129.1 0.011 14.6 14.5 7.3 1 1 5 6 6 6 4 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 CDO73152.1 - 0.0085 16.3 23.5 0.0085 16.3 23.5 8.0 1 1 6 7 7 6 2 Tropomyosin like ATG16 PF08614.11 CDO73152.1 - 0.0092 16.2 166.0 0.0093 16.2 23.7 8.1 2 1 6 8 8 7 5 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 CDO73152.1 - 0.013 14.9 102.3 0.12 11.7 10.8 6.1 1 1 6 7 7 7 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CDO73152.1 - 0.018 15.7 1.3 0.018 15.7 1.3 11.6 4 3 5 11 11 11 0 SlyX YabA PF06156.13 CDO73152.1 - 0.031 14.9 2.0 0.031 14.9 2.0 10.1 3 1 6 10 10 10 0 Initiation control protein YabA AAA_13 PF13166.6 CDO73152.1 - 0.13 10.9 87.7 0.16 10.6 16.3 4.7 1 1 4 5 5 5 0 AAA domain Atg14 PF10186.9 CDO73152.1 - 0.4 9.7 107.4 0.13 11.3 18.6 5.9 1 1 4 5 5 5 0 Vacuolar sorting 38 and autophagy-related subunit 14 PKcGMP_CC PF16808.5 CDO73152.1 - 0.51 10.2 0.0 0.51 10.2 0.0 7.3 7 2 0 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Tropomyosin PF00261.20 CDO73152.1 - 2.1 7.7 129.7 0.096 12.0 45.4 8.0 1 1 6 8 8 8 0 Tropomyosin Fez1 PF06818.15 CDO73152.1 - 2.2 8.7 117.8 0.06 13.8 14.8 6.2 1 1 5 6 6 4 0 Fez1 CENP-F_leu_zip PF10473.9 CDO73152.1 - 2.6 8.1 136.9 2.1 8.3 18.4 8.5 2 1 6 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 CDO73152.1 - 2.9 6.0 89.2 0.0099 14.1 25.1 4.2 1 1 1 2 2 1 0 Septation ring formation regulator, EzrA KNOX2 PF03791.13 CDO73152.1 - 5.7 6.5 9.5 5.7 6.5 0.5 3.6 3 0 0 3 3 3 0 KNOX2 domain WD40 PF00400.32 CDO73153.1 - 2.6e-41 138.8 20.6 9.8e-08 32.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO73153.1 - 4.8e-17 62.0 0.1 0.0038 17.5 0.1 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO73153.1 - 4.5e-05 22.6 0.5 0.44 9.4 0.0 3.7 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CDO73153.1 - 0.00053 19.9 0.0 0.32 10.9 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CDO73153.1 - 0.0011 18.4 0.0 0.22 10.8 0.0 3.2 2 1 1 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 CDO73153.1 - 0.14 10.6 0.0 0.25 9.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain dsrm PF00035.26 CDO73154.1 - 2.1e-06 28.3 0.0 2.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 CDO73155.1 - 7e-06 26.7 0.1 8.8e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif UCH PF00443.29 CDO73156.1 - 8.9e-32 110.6 0.0 1.3e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CDO73156.1 - 3.9e-11 43.1 0.0 7.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CDO73156.1 - 0.002 17.8 0.0 0.0093 15.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rsm22 PF09243.10 CDO73157.1 - 9.7e-40 136.6 0.0 1.1e-24 87.2 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Ribosomal_L1 PF00687.21 CDO73158.1 - 1.8e-20 73.5 0.0 3e-20 72.8 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family MRP-L28 PF09812.9 CDO73159.1 - 2.2e-11 44.1 5.1 9.8e-09 35.5 1.8 2.3 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L28 PCI PF01399.27 CDO73160.1 - 3.1e-20 72.7 1.7 3.3e-20 72.5 0.3 1.9 2 0 0 2 2 2 1 PCI domain DUF5517 PF17639.2 CDO73160.1 - 0.37 11.1 9.4 0.15 12.4 3.5 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5517) PIP5K PF01504.18 CDO73161.1 - 4.6e-40 137.6 0.3 1.7e-35 122.6 0.4 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CDO73161.1 - 1.7e-28 99.5 0.0 2.8e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CDO73161.1 - 1e-16 60.8 11.5 1e-16 60.8 11.5 2.0 2 0 0 2 2 2 1 FYVE zinc finger LTV PF04180.14 CDO73162.1 - 2.7e-101 340.1 9.1 1.5e-93 314.6 4.5 2.1 1 1 1 2 2 2 2 Low temperature viability protein CaM_binding PF07839.11 CDO73162.1 - 0.32 11.7 12.8 1.1 10.1 12.8 1.9 1 0 0 1 1 1 0 Plant calmodulin-binding domain Syntaxin-18_N PF10496.9 CDO73162.1 - 9 6.6 8.1 7 7.0 5.9 2.1 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Bromodomain PF00439.25 CDO73163.1 - 3.7e-59 196.7 0.0 3.4e-20 71.9 0.1 3.7 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 CDO73163.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDO73163.1 - 0.00075 19.7 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 CDO73163.1 - 0.89 10.0 7.3 16 6.0 0.0 4.5 6 0 0 6 6 6 0 HEAT repeats Het-C PF07217.11 CDO73164.1 - 5e-217 721.9 0.0 6.6e-217 721.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cnd3 PF12719.7 CDO73164.1 - 0.25 10.5 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Med11 PF10280.9 CDO73166.1 - 0.0033 17.9 0.1 0.027 14.9 0.0 2.2 2 0 0 2 2 2 1 Mediator complex protein TBCA PF02970.16 CDO73167.1 - 4.3e-22 78.3 4.7 4.3e-22 78.3 4.7 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A HLH PF00010.26 CDO73168.1 - 2.6e-09 36.9 2.9 2.6e-09 36.9 2.9 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.19 CDO73168.1 - 0.15 12.7 5.1 1.1 10.0 2.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein UPF0242 PF06785.11 CDO73168.1 - 0.31 11.1 6.2 0.42 10.7 6.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MPC PF03650.13 CDO73169.1 - 0.026 14.7 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial pyruvate carriers Tenui_PVC2 PF06656.11 CDO73169.1 - 0.14 10.0 0.3 0.18 9.6 0.3 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Baculo_11_kDa PF06143.11 CDO73169.1 - 0.28 10.8 2.9 0.21 11.2 1.0 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family Syndecan PF01034.20 CDO73169.1 - 0.42 10.6 0.1 0.42 10.6 0.1 2.4 3 0 0 3 3 3 0 Syndecan domain HLH PF00010.26 CDO73170.1 - 1.2e-10 41.1 1.5 1.2e-10 41.1 1.5 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FTA4 PF13093.6 CDO73170.1 - 0.0026 17.7 0.1 0.0037 17.2 0.1 1.4 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Shugoshin_N PF07558.11 CDO73170.1 - 0.014 15.2 2.2 0.026 14.4 2.2 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF1192 PF06698.11 CDO73170.1 - 0.034 14.2 0.4 0.1 12.7 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) TolA_bind_tri PF16331.5 CDO73170.1 - 0.056 13.5 1.2 0.056 13.5 1.2 2.6 3 0 0 3 3 3 0 TolA binding protein trimerisation CENP-F_leu_zip PF10473.9 CDO73170.1 - 0.11 12.5 4.8 0.17 11.9 4.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 CDO73170.1 - 0.22 11.4 3.9 0.15 11.9 1.7 1.9 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor APG6_N PF17675.1 CDO73170.1 - 0.23 12.0 4.1 0.45 11.0 4.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 CDO73170.1 - 0.25 11.1 7.6 0.12 12.2 1.1 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 CDO73170.1 - 0.33 10.2 4.9 0.99 8.7 4.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Man-6-P_recep PF02157.15 CDO73171.1 - 5.2e-16 58.5 0.0 6.7e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 CDO73171.1 - 2e-09 37.7 0.0 5.6e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 CDO73171.1 - 2.5e-07 30.8 0.0 6.6e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 Complex1_49kDa PF00346.19 CDO73172.1 - 1.9e-109 365.0 0.0 2.6e-109 364.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CDO73172.1 - 0.006 15.5 0.0 0.013 14.5 0.0 1.6 2 0 0 2 2 2 1 Nickel-dependent hydrogenase SoxZ PF08770.11 CDO73172.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ NIF3 PF01784.18 CDO73173.1 - 1.5e-59 201.6 0.0 1.8e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Glutaredoxin PF00462.24 CDO73174.1 - 3e-19 69.0 0.0 4.2e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CDO73174.1 - 0.00023 21.1 0.0 0.00037 20.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 CDO73174.1 - 0.003 18.0 0.1 0.0061 17.0 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 CDO73174.1 - 0.0033 17.8 0.1 0.0051 17.2 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 CDO73174.1 - 0.047 14.1 0.0 0.063 13.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 CDO73174.1 - 0.084 13.0 0.1 2.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin CSTF_C PF14304.6 CDO73175.1 - 4.7e-10 38.9 1.5 5.3e-10 38.7 0.1 1.8 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal Metal_resist PF13801.6 CDO73175.1 - 2.6 8.3 10.9 0.3 11.3 0.9 2.2 1 1 1 2 2 2 0 Heavy-metal resistance Adaptin_N PF01602.20 CDO73176.1 - 6.7e-99 331.8 10.6 1e-98 331.2 10.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 CDO73176.1 - 7e-61 203.9 0.0 1.9e-60 202.5 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CDO73176.1 - 6.2e-54 181.7 0.1 2e-53 180.1 0.0 1.9 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 CDO73176.1 - 1.7e-08 34.8 2.1 0.029 14.8 0.0 5.3 2 1 2 6 6 5 3 HEAT repeats HEAT PF02985.22 CDO73176.1 - 8.8e-07 28.7 0.2 0.33 11.3 0.0 5.3 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 CDO73176.1 - 3.3e-06 27.2 10.3 0.0018 18.4 0.2 4.3 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 CDO73176.1 - 1.5e-05 24.5 7.8 0.0049 16.3 1.2 3.6 1 1 2 3 3 3 2 Family of unknown function (DUF5578) DUF5071 PF16804.5 CDO73176.1 - 0.00021 21.5 1.8 0.1 12.8 0.0 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF5071) Coatomer_g_Cpla PF16381.5 CDO73176.1 - 0.00098 19.2 0.0 0.0034 17.5 0.0 2.0 2 0 0 2 2 1 1 Coatomer subunit gamma-1 C-terminal appendage platform Gemini_V2 PF01524.17 CDO73176.1 - 0.0063 16.7 0.1 0.25 11.5 0.0 2.8 2 0 0 2 2 2 1 Geminivirus V2 protein MCRA PF06100.11 CDO73176.1 - 0.027 13.3 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 MCRA family ParcG PF10274.9 CDO73176.1 - 0.031 14.4 3.6 0.61 10.2 0.0 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein DNA_alkylation PF08713.11 CDO73176.1 - 0.051 13.3 0.1 4.9 6.8 0.0 3.2 3 0 0 3 3 3 0 DNA alkylation repair enzyme RTP1_C1 PF10363.9 CDO73176.1 - 0.058 13.6 3.1 0.32 11.2 0.0 3.3 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Meis_PKNOX_N PF16493.5 CDO73176.1 - 0.088 13.2 0.3 0.4 11.0 0.3 2.2 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 PAH PF02671.21 CDO73176.1 - 0.091 12.9 0.0 8.7 6.6 0.0 2.9 2 0 0 2 2 2 0 Paired amphipathic helix repeat RasGEF_N_2 PF14663.6 CDO73176.1 - 0.16 12.3 5.6 4 7.9 0.0 4.6 3 1 2 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Transp_cyt_pur PF02133.15 CDO73177.1 - 1.5e-22 80.0 19.8 1.1e-12 47.5 4.6 2.2 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_transf_22 PF03901.17 CDO73179.1 - 1.4e-90 304.5 16.1 1.7e-90 304.2 16.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family FtsX PF02687.21 CDO73180.1 - 0.16 12.4 0.1 0.16 12.4 0.1 3.1 2 1 1 3 3 3 0 FtsX-like permease family Sin3a_C PF16879.5 CDO73182.1 - 3.1e-67 227.3 0.0 7.1e-37 127.7 0.0 3.2 2 1 1 3 3 3 2 C-terminal domain of Sin3a protein PAH PF02671.21 CDO73182.1 - 1.6e-42 143.4 11.8 2.1e-18 66.2 0.0 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CDO73182.1 - 1.4e-38 130.9 0.1 3.1e-38 129.8 0.1 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor Zn-C2H2_12 PF18112.1 CDO73182.1 - 0.005 17.3 0.1 0.005 17.3 0.1 2.0 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain PWI PF01480.17 CDO73182.1 - 0.12 12.7 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 PWI domain Trypan_PARP PF05887.11 CDO73183.1 - 0.52 10.3 10.3 0.74 9.8 10.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SH3_1 PF00018.28 CDO73184.1 - 7.2e-12 44.7 0.1 1.3e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CDO73184.1 - 8.7e-10 38.1 0.0 1.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CDO73184.1 - 2.9e-09 36.7 0.0 5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CDO73184.1 - 0.072 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain zf-C3HC4 PF00097.25 CDO73185.1 - 3.6e-08 33.1 9.1 6.2e-08 32.4 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO73185.1 - 2.1e-06 27.9 10.2 3.6e-06 27.2 10.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CDO73185.1 - 3.9e-06 26.8 10.2 7.5e-06 25.9 7.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDO73185.1 - 7.7e-06 25.7 6.2 1.3e-05 25.0 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDO73185.1 - 3e-05 23.8 8.3 0.00032 20.5 9.2 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDO73185.1 - 5.8e-05 23.2 10.3 9.4e-05 22.5 10.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDO73185.1 - 0.00011 22.1 6.5 0.00019 21.3 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.20 CDO73185.1 - 0.0012 18.5 7.5 0.0025 17.5 7.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.6 CDO73185.1 - 0.018 14.9 6.9 0.039 13.8 6.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CDO73185.1 - 0.023 14.5 5.0 0.041 13.7 5.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 CDO73185.1 - 0.37 11.1 5.0 0.74 10.1 5.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CDO73185.1 - 0.76 9.6 8.1 3.7 7.4 4.3 2.6 2 1 0 2 2 2 0 RING-like zinc finger Wbp11 PF09429.10 CDO73186.1 - 3.1e-17 62.7 7.0 6.7e-17 61.7 7.0 1.6 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 CDO73186.1 - 1.2e-14 54.8 9.3 1.2e-14 54.8 9.3 9.0 6 1 0 6 6 6 1 mRNA biogenesis factor Cwf_Cwc_15 PF04889.12 CDO73186.1 - 0.099 12.4 9.3 0.017 14.9 5.6 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Latarcin PF10279.9 CDO73186.1 - 0.45 10.9 2.9 0.8 10.1 2.9 1.4 1 0 0 1 1 1 0 Latarcin precursor Spc7 PF08317.11 CDO73186.1 - 0.78 8.6 7.4 1.1 8.1 7.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PBP_sp32 PF07222.12 CDO73186.1 - 1.4 8.4 4.7 2.2 7.7 4.7 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 LCD1 PF09798.9 CDO73186.1 - 4.8 5.6 5.5 6.4 5.2 5.5 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein F-box-like PF12937.7 CDO73188.1 - 0.0073 16.2 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like Aspzincin_M35 PF14521.6 CDO73189.1 - 3.2e-45 154.3 9.4 3.5e-45 154.1 9.4 1.0 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 CDO73189.1 - 0.92 8.3 9.9 1.3 7.8 9.9 1.4 1 1 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 CDO73190.1 - 4.2e-47 160.3 6.7 8.3e-47 159.4 6.7 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 CDO73190.1 - 3.8e-09 35.9 10.6 1.9e-08 33.6 10.6 2.0 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.6 CDO73190.1 - 0.00076 19.1 2.0 0.29 10.7 0.2 2.1 1 1 0 2 2 2 2 Putative peptidase family Flocculin PF00624.18 CDO73190.1 - 7.7 6.8 13.8 0.22 11.8 6.2 2.3 2 0 0 2 2 2 0 Flocculin repeat Metallophos PF00149.28 CDO73191.1 - 8.1e-11 42.8 0.6 3.9e-10 40.6 0.1 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDO73191.1 - 0.00092 19.4 0.1 0.013 15.7 0.1 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain NAT PF04768.13 CDO73192.1 - 2.2e-34 118.5 0.0 5.5e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase CRF-BP PF05428.11 CDO73192.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Mito_carr PF00153.27 CDO73194.1 - 4.3e-52 174.0 6.6 1.3e-19 69.9 0.1 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Fasciclin PF02469.22 CDO73195.1 - 6.4e-62 207.5 0.0 1.8e-15 57.3 0.0 5.3 5 1 0 5 5 5 5 Fasciclin domain Rav1p_C PF12234.8 CDO73196.1 - 1.9e-202 674.1 0.0 2.4e-202 673.8 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal GDI PF00996.18 CDO73197.1 - 8.7e-223 739.6 0.0 1e-222 739.4 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor PK PF00224.21 CDO73198.1 - 4.8e-163 542.0 1.2 6.3e-163 541.6 1.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CDO73198.1 - 7.9e-38 129.3 0.1 3.3e-37 127.3 0.0 2.2 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CDO73198.1 - 5.6e-05 22.4 0.7 0.00022 20.5 0.6 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 CDO73198.1 - 0.0041 16.2 0.1 0.051 12.6 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Gly_transf_sug PF04488.15 CDO73199.1 - 3.4e-05 24.4 0.0 7.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CDO73199.1 - 0.12 11.7 0.2 0.19 11.1 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein LMWPc PF01451.21 CDO73200.1 - 3.4e-31 108.5 0.0 3e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase DraK_HK_N PF18092.1 CDO73200.1 - 0.097 13.1 0.0 0.79 10.2 0.0 2.2 2 1 0 2 2 2 0 DraK Histidine Kinase N-terminal domain Aldedh PF00171.22 CDO73201.1 - 1.3e-123 412.9 0.1 1.6e-123 412.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family T6SS_VasJ PF16989.5 CDO73201.1 - 0.1 12.1 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ SH3BGR PF04908.15 CDO73202.1 - 0.0001 22.4 0.3 0.077 13.2 0.3 3.4 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Seipin PF06775.14 CDO73203.1 - 2e-19 70.5 0.0 1.3e-18 67.8 0.0 1.9 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) G0-G1_switch_2 PF15103.6 CDO73203.1 - 0.029 14.8 0.1 0.074 13.5 0.1 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 MAP17 PF15807.5 CDO73203.1 - 0.084 13.1 0.4 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 NPR3 PF03666.13 CDO73203.1 - 0.21 10.3 0.6 0.29 9.9 0.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LCCL PF03815.19 CDO73206.1 - 7.1e-15 54.9 0.0 1.2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 LCCL domain WW PF00397.26 CDO73208.1 - 7.6e-05 22.7 2.4 0.00014 21.9 2.4 1.5 1 0 0 1 1 1 1 WW domain DUF4603 PF15376.6 CDO73208.1 - 0.14 9.5 1.1 0.18 9.2 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) TRAPPC-Trs85 PF12739.7 CDO73209.1 - 9.4e-25 87.4 0.0 1.6e-19 70.2 0.0 2.3 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Mpv17_PMP22 PF04117.12 CDO73210.1 - 5.9e-10 39.2 1.6 9.4e-10 38.6 1.6 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mito_carr PF00153.27 CDO73211.1 - 1e-33 115.1 4.4 6.7e-17 61.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 CDO73212.1 - 0.0077 16.1 0.2 0.024 14.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CDO73212.1 - 0.033 14.6 1.2 1.1 9.7 0.4 3.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDO73212.1 - 0.71 9.7 7.1 0.25 11.1 2.2 2.6 3 0 0 3 3 3 0 Leucine rich repeat Fez1 PF06818.15 CDO73213.1 - 0.00067 20.2 15.9 0.00067 20.2 15.9 6.1 1 1 3 5 5 5 1 Fez1 TMF_TATA_bd PF12325.8 CDO73213.1 - 0.0011 19.2 7.5 0.0011 19.2 7.5 10.2 1 1 8 10 10 10 3 TATA element modulatory factor 1 TATA binding DUF4349 PF14257.6 CDO73213.1 - 0.0027 17.2 1.1 0.0027 17.2 1.1 7.6 4 1 3 7 7 7 2 Domain of unknown function (DUF4349) DUF4200 PF13863.6 CDO73213.1 - 0.011 16.2 4.5 0.011 16.2 4.5 8.7 3 1 6 9 9 9 0 Domain of unknown function (DUF4200) Filament PF00038.21 CDO73213.1 - 0.21 11.2 120.8 0.75 9.3 25.9 6.0 1 1 3 5 5 5 0 Intermediate filament protein Ras PF00071.22 CDO73214.1 - 1.2e-38 132.3 0.0 1.5e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO73214.1 - 1.2e-12 48.1 0.0 1.7e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO73214.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Exo_endo_phos PF03372.23 CDO73215.1 - 3.9e-20 72.4 0.0 6.1e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGEF PF00621.20 CDO73216.1 - 2.2e-17 63.9 0.0 3.9e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Fungal_trans PF04082.18 CDO73218.1 - 1.3e-11 44.1 0.0 2.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FlxA PF14282.6 CDO73218.1 - 0.093 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 FlxA-like protein Zn_clus PF00172.18 CDO73218.1 - 0.15 12.2 1.8 0.39 10.9 1.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH PF00642.24 CDO73219.1 - 1.3e-13 50.5 21.1 2.1e-05 24.3 0.6 3.8 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDO73219.1 - 3.1e-10 39.8 26.2 8.7e-07 28.8 2.1 3.9 4 0 0 4 4 4 3 Zinc finger domain Torus PF16131.5 CDO73219.1 - 5.5e-07 30.2 16.4 0.00048 20.8 0.5 4.0 1 1 3 4 4 4 3 Torus domain zf-CCCH_4 PF18044.1 CDO73219.1 - 2.1e-05 24.2 0.4 2.1e-05 24.2 0.4 4.2 5 0 0 5 5 5 1 CCCH-type zinc finger zf-CCHC PF00098.23 CDO73219.1 - 0.00022 21.1 4.3 0.00022 21.1 4.3 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_2 PF14608.6 CDO73219.1 - 0.0018 18.7 22.5 0.0072 16.8 0.3 4.2 4 0 0 4 4 4 2 RNA-binding, Nab2-type zinc finger zf-CCHC_3 PF13917.6 CDO73219.1 - 0.016 15.2 1.9 0.032 14.2 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCCH_3 PF15663.5 CDO73219.1 - 0.94 9.7 12.6 2.3 8.5 0.4 3.3 1 1 2 3 3 3 0 Zinc-finger containing family zf-CCHC_2 PF13696.6 CDO73219.1 - 1.3 8.9 9.4 0.14 12.0 3.6 2.6 2 0 0 2 2 2 0 Zinc knuckle Herpes_UL37_1 PF03970.13 CDO73220.1 - 0.0062 15.8 0.2 0.0097 15.1 0.2 1.2 1 0 0 1 1 1 1 Herpesvirus UL37 tegument protein Peptidase_M16_C PF05193.21 CDO73221.1 - 5.5e-16 59.1 0.0 8.5e-12 45.5 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDO73221.1 - 1.5e-11 44.5 0.1 1.7e-09 37.8 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 CDO73221.1 - 0.00011 21.4 1.2 0.0018 17.4 1.2 2.2 1 1 0 1 1 1 1 Peptidase M16C associated DUF1949 PF09186.11 CDO73221.1 - 0.022 14.6 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) RQC PF09382.10 CDO73221.1 - 0.091 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 RQC domain NUFIP1 PF10453.9 CDO73222.1 - 2e-19 69.2 1.0 4.3e-19 68.1 1.0 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) MAP7 PF05672.11 CDO73222.1 - 0.014 15.1 0.9 0.029 14.1 0.9 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family API5 PF05918.11 CDO73222.1 - 2.5 6.8 4.6 3.9 6.2 4.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) KH_1 PF00013.29 CDO73223.1 - 1.2e-42 143.6 9.0 2.3e-16 59.4 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CDO73223.1 - 6.5e-11 42.0 0.1 0.0051 16.7 0.0 3.5 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 CDO73223.1 - 3.1e-10 39.7 3.2 0.018 14.8 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CDO73223.1 - 1.9e-05 24.6 3.3 0.021 14.9 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain Ribosomal_L13 PF00572.18 CDO73224.1 - 1.2e-11 44.9 0.0 6.9e-10 39.2 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 PP-binding PF00550.25 CDO73225.1 - 1.8e-14 53.8 0.4 2.7e-14 53.3 0.4 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CDO73225.1 - 7e-06 26.2 0.3 9.8e-06 25.7 0.3 1.2 1 0 0 1 1 1 1 Acyl-carrier AAA_lid_4 PF17864.1 CDO73225.1 - 0.22 11.3 1.8 0.61 9.9 1.9 1.9 1 1 1 2 2 2 0 RuvB AAA lid domain SGL PF08450.12 CDO73226.1 - 1e-54 185.7 0.0 1.3e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ PF01011.21 CDO73226.1 - 0.061 13.3 2.9 1.2 9.1 0.2 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat Phytase-like PF13449.6 CDO73226.1 - 0.12 12.3 0.0 2.1 8.2 0.0 2.0 1 1 1 2 2 2 0 Esterase-like activity of phytase Ribosomal_L17 PF01196.19 CDO73227.1 - 2.2e-32 111.8 0.3 1.1e-29 103.2 0.0 2.8 2 1 0 2 2 2 1 Ribosomal protein L17 GDPD PF03009.17 CDO73228.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family ADH_N PF08240.12 CDO73229.1 - 2e-31 108.1 0.3 4e-31 107.1 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO73229.1 - 5.7e-16 58.7 0.0 2.9e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CDO73229.1 - 2.5e-05 23.7 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 CDO73229.1 - 2.7e-05 24.0 0.0 9.1e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TrkA_N PF02254.18 CDO73229.1 - 0.032 14.5 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain FANCL_C PF11793.8 CDO73229.1 - 0.045 13.9 0.4 0.094 12.9 0.4 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Methyltransf_11 PF08241.12 CDO73229.1 - 0.056 14.1 0.0 0.16 12.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CDO73229.1 - 0.11 13.3 0.0 0.32 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain ADH_N_assoc PF13823.6 CDO73229.1 - 0.36 10.8 0.0 0.36 10.8 0.0 2.2 3 0 0 3 3 3 0 Alcohol dehydrogenase GroES-associated Peptidase_U4 PF03419.13 CDO73231.1 - 0.013 14.8 1.7 0.017 14.4 1.7 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA RNase_T PF00929.24 CDO73232.1 - 5.1e-25 88.9 0.0 1e-24 87.9 0.0 1.5 2 0 0 2 2 2 1 Exonuclease E1_DerP2_DerF2 PF02221.15 CDO73232.1 - 3.6e-22 79.2 0.4 5.4e-22 78.7 0.4 1.3 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 CDO73232.1 - 0.0014 19.0 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 ML-like domain Cellulase PF00150.18 CDO73233.1 - 9.2e-24 84.3 1.5 1.2e-23 84.0 1.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 CDO73233.1 - 7.6e-05 22.2 0.3 0.0025 17.2 0.0 3.0 2 2 0 2 2 2 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 CDO73233.1 - 0.0074 15.4 0.0 0.032 13.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ipi1_N PF12333.8 CDO73234.1 - 3.4e-08 34.0 0.0 1.6e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation DPBB_1 PF03330.18 CDO73236.1 - 9.6e-08 32.2 0.0 1.2e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 Lytic transglycolase JAB PF01398.21 CDO73237.1 - 7.7e-13 48.5 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 CDO73237.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Plavaka PF18759.1 CDO73238.1 - 1.4e-44 152.6 0.0 2e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase NPH3 PF03000.14 CDO73240.1 - 0.053 13.2 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 NPH3 family tRNA_synt_1c_R1 PF04558.15 CDO73240.1 - 0.078 13.0 1.4 0.42 10.6 0.1 2.1 1 1 1 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 T2SSK PF03934.13 CDO73240.1 - 0.079 12.3 2.1 0.19 11.1 2.1 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein K Sec34 PF04136.15 CDO73240.1 - 0.093 12.6 0.1 0.093 12.6 0.1 1.7 3 0 0 3 3 3 0 Sec34-like family Band_7 PF01145.25 CDO73240.1 - 0.12 12.4 1.0 0.17 11.9 1.0 1.3 1 0 0 1 1 1 0 SPFH domain / Band 7 family Fungal_trans PF04082.18 CDO73241.1 - 4.9e-16 58.6 0.2 9.4e-16 57.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SUIM_assoc PF16619.5 CDO73241.1 - 3 8.0 10.3 1.3 9.2 5.0 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AATF-Che1 PF13339.6 CDO73242.1 - 1.5e-13 51.6 0.0 1.5e-13 51.6 0.0 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 CDO73242.1 - 0.00066 20.1 0.5 0.0027 18.2 0.0 2.3 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal Nop14 PF04147.12 CDO73242.1 - 0.0048 15.2 8.8 0.0055 15.0 8.8 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 CDO73242.1 - 0.12 11.8 16.2 0.15 11.5 16.2 1.1 1 0 0 1 1 1 0 SDA1 LAP1C PF05609.12 CDO73242.1 - 0.93 8.5 11.0 1.2 8.2 11.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Roughex PF06020.11 CDO73242.1 - 1.4 8.0 8.8 1.7 7.6 8.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Zip PF02535.22 CDO73242.1 - 1.9 7.6 8.5 2.4 7.3 8.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ras PF00071.22 CDO73243.1 - 5.3e-36 123.7 0.0 1.2e-34 119.3 0.0 2.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CDO73243.1 - 9.5e-12 45.2 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Clathrin PF00637.20 CDO73244.1 - 1.6e-204 670.0 35.5 2.1e-33 115.2 0.2 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 CDO73244.1 - 4.7e-37 124.5 0.3 7.2e-07 29.2 0.1 6.8 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 CDO73244.1 - 9.1e-31 105.6 1.0 3.1e-30 103.9 0.1 2.6 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 CDO73244.1 - 4.8e-12 45.0 0.3 1.7e-11 43.2 0.1 2.2 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 CDO73244.1 - 3.9e-05 22.9 5.2 0.55 9.2 0.0 4.8 5 0 0 5 5 5 2 Coatomer WD associated region TPR_14 PF13428.6 CDO73244.1 - 0.0079 16.9 17.0 0.99 10.4 0.1 8.9 10 1 1 11 11 11 1 Tetratricopeptide repeat Acetyltransf_15 PF17013.5 CDO73244.1 - 0.053 13.0 0.1 0.31 10.5 0.0 2.3 2 0 0 2 2 2 0 Putative acetyl-transferase TPR_7 PF13176.6 CDO73244.1 - 0.27 11.4 5.9 21 5.4 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDO73244.1 - 0.48 10.3 8.0 48 4.0 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDO73244.1 - 1.8 8.9 8.8 69 3.9 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Fungal_trans PF04082.18 CDO73245.1 - 2.1e-20 72.9 0.7 4.1e-20 71.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CDO73245.1 - 2.1e-05 24.5 9.2 3.8e-05 23.7 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDCD2_C PF04194.13 CDO73246.1 - 2e-43 148.5 0.0 2e-43 148.5 0.0 3.0 3 1 1 4 4 4 1 Programmed cell death protein 2, C-terminal putative domain ATP11 PF06644.11 CDO73246.1 - 0.027 14.3 0.4 0.037 13.8 0.4 1.2 1 0 0 1 1 1 0 ATP11 protein FlpD PF02662.16 CDO73246.1 - 0.03 14.3 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit zf-RING_7 PF02591.15 CDO73246.1 - 0.25 11.5 3.9 11 6.3 0.1 2.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain YdjO PF14169.6 CDO73246.1 - 0.36 10.6 7.6 5.5 6.8 0.9 3.5 3 0 0 3 3 3 0 Cold-inducible protein YdjO zinc_ribbon_9 PF14369.6 CDO73246.1 - 0.66 10.3 3.6 15 5.9 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon HemY_N PF07219.13 CDO73246.1 - 0.74 10.0 4.4 1.2 9.3 4.4 1.3 1 0 0 1 1 1 0 HemY protein N-terminus PH PF00169.29 CDO73247.1 - 2.6e-05 24.7 0.0 4.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 PH domain DUF737 PF05300.11 CDO73247.1 - 0.00017 22.1 13.6 0.00031 21.2 13.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF737) CBP_BcsG PF11658.8 CDO73247.1 - 5.9 5.2 5.6 8.8 4.6 5.6 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Asp-B-Hydro_N PF05279.11 CDO73247.1 - 7.9 6.5 17.2 12 5.9 17.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATP-synt_ab PF00006.25 CDO73248.1 - 3.2e-73 245.9 0.0 4.4e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CDO73248.1 - 2.9e-42 144.0 0.1 4.8e-42 143.3 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CDO73248.1 - 1.1e-17 64.3 0.6 2.4e-17 63.2 0.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L21p PF00829.21 CDO73249.1 - 2.1e-25 88.9 0.2 2.7e-25 88.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein UvrA_inter PF17760.1 CDO73249.1 - 0.02 15.0 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 UvrA interaction domain FF PF01846.19 CDO73250.1 - 2.3e-25 88.5 6.5 7e-09 35.7 0.0 6.3 6 0 0 6 6 6 4 FF domain PX PF00787.24 CDO73250.1 - 2e-21 76.1 0.0 8.6e-21 74.0 0.0 2.1 1 0 0 1 1 1 1 PX domain WW PF00397.26 CDO73250.1 - 1.1e-13 51.0 16.9 1.6e-07 31.3 4.7 2.9 2 0 0 2 2 2 2 WW domain Vps5 PF09325.10 CDO73250.1 - 0.00041 20.0 19.0 0.0052 16.4 1.4 3.0 3 0 0 3 3 3 2 Vps5 C terminal like LuxT_C PF18285.1 CDO73250.1 - 0.24 11.9 0.6 0.94 10.1 0.6 2.0 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain DUF5339 PF17274.2 CDO73250.1 - 0.26 12.2 4.7 0.66 10.9 2.9 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5339) FliD_N PF02465.18 CDO73250.1 - 7.7 7.3 11.8 0.15 12.8 2.0 3.1 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus PQ-loop PF04193.14 CDO73251.1 - 9e-14 51.0 3.0 9e-14 51.0 3.0 1.8 2 0 0 2 2 2 1 PQ loop repeat ER_lumen_recept PF00810.18 CDO73251.1 - 0.059 14.2 1.4 0.074 13.9 1.2 1.4 1 1 0 1 1 1 0 ER lumen protein retaining receptor UDPGT PF00201.18 CDO73252.1 - 1.2e-17 63.9 0.1 1.7e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO73252.1 - 3.8e-05 23.7 0.0 6.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF2408 PF10303.9 CDO73253.1 - 1.2e-64 216.9 9.7 1.1e-46 158.8 1.5 4.9 3 1 1 4 4 4 3 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 CDO73253.1 - 0.046 14.1 5.0 14 6.2 0.3 4.2 4 0 0 4 4 4 0 Snapin/Pallidin DUF4407 PF14362.6 CDO73253.1 - 0.08 12.3 1.0 0.14 11.5 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Use1 PF09753.9 CDO73253.1 - 0.085 12.6 1.9 0.23 11.2 1.9 1.8 1 0 0 1 1 1 0 Membrane fusion protein Use1 CK2S PF15011.6 CDO73253.1 - 0.14 12.1 2.3 0.51 10.2 0.3 2.7 2 0 0 2 2 2 0 Casein Kinase 2 substrate ZapA PF05164.13 CDO73253.1 - 0.37 11.3 0.0 0.37 11.3 0.0 2.8 3 1 0 3 3 3 0 Cell division protein ZapA MscS_porin PF12795.7 CDO73253.1 - 0.56 9.7 9.3 0.17 11.4 4.8 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ATG16 PF08614.11 CDO73253.1 - 3 8.0 14.4 7.5 6.7 0.0 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.7 CDO73254.1 - 7.3e-49 165.6 35.8 9.5e-49 165.2 35.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 CDO73254.1 - 2.9e-12 46.5 34.5 1.5e-05 24.5 5.5 3.1 1 1 2 3 3 3 3 Tropomyosin DUF3450 PF11932.8 CDO73254.1 - 0.00011 21.7 27.9 0.011 15.1 14.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 CDO73254.1 - 0.00051 20.3 21.9 0.00051 20.3 21.9 2.1 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.13 CDO73254.1 - 0.00069 20.0 16.4 0.00069 20.0 16.4 2.2 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region KELK PF15796.5 CDO73254.1 - 0.00076 19.9 7.1 0.00076 19.9 7.1 4.0 2 2 1 3 3 2 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase TPR_MLP1_2 PF07926.12 CDO73254.1 - 0.0013 18.8 39.0 0.019 15.0 14.7 3.3 1 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 CDO73254.1 - 0.0019 18.7 42.1 0.088 13.3 26.5 2.2 1 1 1 2 2 2 2 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 CDO73254.1 - 0.0025 17.8 36.0 0.07 13.2 16.3 3.0 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 CDO73254.1 - 0.0027 17.8 39.0 0.26 11.4 16.8 2.7 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain GAS PF13851.6 CDO73254.1 - 0.0038 16.6 35.0 0.035 13.4 10.5 3.1 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding FPP PF05911.11 CDO73254.1 - 0.0068 14.7 22.3 0.0086 14.3 22.3 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil HOOK PF05622.12 CDO73254.1 - 0.0087 14.3 23.5 0.011 13.9 23.5 1.1 1 0 0 1 1 1 1 HOOK protein DUF4200 PF13863.6 CDO73254.1 - 0.011 16.2 37.1 0.066 13.6 12.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CALCOCO1 PF07888.11 CDO73254.1 - 0.012 14.5 28.9 0.019 13.8 28.9 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HrpB7 PF09486.10 CDO73254.1 - 0.016 15.6 25.0 0.28 11.6 8.5 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) BRE1 PF08647.11 CDO73254.1 - 0.02 14.9 32.3 0.17 12.0 10.3 3.4 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 CDO73254.1 - 0.021 15.0 32.6 0.06 13.5 15.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG17 PF04108.12 CDO73254.1 - 0.024 13.8 2.0 0.024 13.8 2.0 3.0 1 1 2 3 3 3 0 Autophagy protein Apg17 ADIP PF11559.8 CDO73254.1 - 0.025 14.6 32.0 0.6 10.2 6.9 3.4 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 CDO73254.1 - 0.029 13.8 23.9 0.39 10.0 24.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Laminin_II PF06009.12 CDO73254.1 - 0.033 14.2 3.5 0.033 14.2 3.5 2.5 1 1 2 3 3 3 0 Laminin Domain II HMMR_N PF15905.5 CDO73254.1 - 0.052 13.0 30.2 0.072 12.6 30.2 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FliD_C PF07195.12 CDO73254.1 - 0.058 12.8 14.6 0.34 10.3 14.7 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TMF_TATA_bd PF12325.8 CDO73254.1 - 0.076 13.2 31.9 0.032 14.4 9.9 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 CDO73254.1 - 0.12 12.5 16.4 0.42 10.7 4.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CDO73254.1 - 0.12 11.3 34.8 0.18 10.6 13.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 CDO73254.1 - 0.12 12.2 30.4 0.89 9.3 12.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) EzrA PF06160.12 CDO73254.1 - 0.19 9.8 28.1 0.02 13.1 10.7 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FliJ PF02050.16 CDO73254.1 - 0.2 11.9 31.4 0.44 10.8 13.8 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein Fez1 PF06818.15 CDO73254.1 - 0.23 11.9 29.0 0.085 13.3 25.2 1.8 1 1 1 2 2 2 0 Fez1 Uds1 PF15456.6 CDO73254.1 - 0.23 11.6 25.9 0.85 9.8 8.0 2.3 1 1 1 2 2 2 0 Up-regulated During Septation IFT57 PF10498.9 CDO73254.1 - 0.27 10.2 24.8 2.2 7.2 11.6 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ERM PF00769.19 CDO73254.1 - 0.31 10.8 40.1 8.1 6.2 40.0 2.1 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Syntaxin_2 PF14523.6 CDO73254.1 - 0.31 11.4 16.3 0.2 12.0 11.3 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Flagellin_N PF00669.20 CDO73254.1 - 0.32 11.1 6.9 1.2 9.3 6.7 2.0 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region FUSC PF04632.12 CDO73254.1 - 0.38 9.2 9.9 0.45 9.0 9.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PspA_IM30 PF04012.12 CDO73254.1 - 0.39 10.3 33.3 1.9 8.0 9.8 2.2 1 1 1 2 2 2 0 PspA/IM30 family Fib_alpha PF08702.10 CDO73254.1 - 0.45 10.7 18.2 2.2 8.4 4.7 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 CDO73254.1 - 0.45 10.8 35.5 1.1 9.5 17.6 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Sec34 PF04136.15 CDO73254.1 - 0.47 10.3 14.9 0.028 14.3 3.5 2.8 1 1 2 3 3 3 0 Sec34-like family PRKG1_interact PF15898.5 CDO73254.1 - 0.5 11.3 27.5 2.2 9.2 10.7 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TRAF_BIRC3_bd PF16673.5 CDO73254.1 - 0.61 9.9 15.9 1.9 8.4 4.5 3.1 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain BST2 PF16716.5 CDO73254.1 - 0.61 10.7 28.1 4.6 7.9 3.4 3.6 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 NPV_P10 PF05531.12 CDO73254.1 - 0.77 10.3 9.2 4.7 7.8 0.5 3.4 2 1 2 4 4 3 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 CDO73254.1 - 0.8 9.9 35.5 2.5 8.3 14.2 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 CDO73254.1 - 0.81 8.5 30.1 3 6.6 30.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4201 PF13870.6 CDO73254.1 - 0.85 9.3 27.9 2.1 8.1 9.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) SurA_N PF09312.11 CDO73254.1 - 0.91 9.6 11.0 0.17 12.0 5.6 2.1 1 1 1 2 2 2 0 SurA N-terminal domain WXG100 PF06013.12 CDO73254.1 - 1 9.7 17.6 4.6 7.5 4.2 3.8 3 1 0 4 4 3 0 Proteins of 100 residues with WXG AAA_13 PF13166.6 CDO73254.1 - 1.1 7.8 25.4 3.2 6.3 25.4 1.6 1 1 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.22 CDO73254.1 - 1.2 9.4 30.5 0.74 10.1 17.1 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HisKA_3 PF07730.13 CDO73254.1 - 1.3 9.6 13.4 8.9 6.9 3.5 4.0 2 1 1 3 3 3 0 Histidine kinase DUF883 PF05957.13 CDO73254.1 - 1.4 9.5 18.5 6.1 7.5 1.1 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Lectin_N PF03954.14 CDO73254.1 - 1.4 8.6 15.7 35 4.1 3.2 3.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF5082 PF16888.5 CDO73254.1 - 1.5 9.1 22.6 14 6.0 15.0 3.4 1 1 1 2 2 1 0 Domain of unknown function (DUF5082) HHV-5_US34A PF17087.5 CDO73254.1 - 1.5 9.0 8.5 0.58 10.3 3.1 2.5 2 1 0 2 2 2 0 Herpesvirus US34A protein family DUF3584 PF12128.8 CDO73254.1 - 1.5 6.2 31.6 3.2 5.2 31.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Lebercilin PF15619.6 CDO73254.1 - 1.5 8.4 35.4 2.8 7.6 14.1 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Cep57_CLD_2 PF14197.6 CDO73254.1 - 1.6 8.9 28.8 2.2 8.5 6.4 4.2 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 DUF702 PF05142.12 CDO73254.1 - 1.7 9.1 7.9 16 6.0 7.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF702) YscO PF07321.12 CDO73254.1 - 1.7 8.6 37.8 6.3 6.8 14.9 2.4 1 1 1 2 2 2 0 Type III secretion protein YscO Med21 PF11221.8 CDO73254.1 - 1.9 8.7 28.5 29 4.9 27.0 2.8 1 1 1 2 2 2 0 Subunit 21 of Mediator complex KxDL PF10241.9 CDO73254.1 - 2 8.8 22.1 2.7 8.4 4.8 3.5 1 1 2 4 4 4 0 Uncharacterized conserved protein ArAE_2_N PF10337.9 CDO73254.1 - 2.2 7.2 6.8 2.8 6.9 6.8 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal T3SSipB PF16535.5 CDO73254.1 - 2.5 8.5 24.0 6.4 7.2 18.8 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF573 PF04504.14 CDO73254.1 - 2.7 8.7 10.8 3 8.6 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function, DUF573 TMF_DNA_bd PF12329.8 CDO73254.1 - 2.8 8.0 38.1 1.3 9.0 19.2 3.4 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Swi5 PF07061.11 CDO73254.1 - 2.9 8.0 27.3 0.62 10.2 5.1 4.1 1 1 3 4 4 4 0 Swi5 DUF4164 PF13747.6 CDO73254.1 - 2.9 8.2 29.9 8.3 6.8 11.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Exonuc_VII_L PF02601.15 CDO73254.1 - 4.8 6.7 21.6 24 4.4 21.6 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 CDO73254.1 - 5.7 5.9 26.2 2e+03 -2.4 26.2 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 CDO73254.1 - 6 7.2 24.0 3 8.2 8.7 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fmp27_WPPW PF10359.9 CDO73254.1 - 6 5.6 24.4 0.61 8.9 10.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4795 PF16043.5 CDO73254.1 - 6.2 6.4 28.1 14 5.2 28.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF16 PF01519.16 CDO73254.1 - 7.1 7.2 21.4 2 8.9 8.7 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF16 Fzo_mitofusin PF04799.13 CDO73254.1 - 8.2 6.0 17.8 1 8.9 4.6 2.7 1 1 3 4 4 4 0 fzo-like conserved region SHE3 PF17078.5 CDO73254.1 - 9.4 5.9 29.4 3.9 7.1 11.0 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF2203 PF09969.9 CDO73254.1 - 9.8 6.9 23.7 3.8 8.2 6.1 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Tropomyosin_1 PF12718.7 CDO73255.1 - 6.3e-26 91.2 25.8 5.3e-23 81.7 16.3 2.0 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 CDO73255.1 - 1e-10 41.4 25.3 2.8e-06 26.9 9.9 2.1 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.6 CDO73255.1 - 8.8e-06 25.2 22.3 1.1e-05 24.9 22.3 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 CDO73255.1 - 0.0003 21.1 24.5 0.0004 20.6 24.5 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 ADIP PF11559.8 CDO73255.1 - 0.0003 20.9 19.9 0.043 13.9 9.9 2.2 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 CDO73255.1 - 0.00068 18.6 22.3 0.00079 18.4 22.3 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Cnn_1N PF07989.11 CDO73255.1 - 0.00097 19.3 10.4 0.00097 19.3 10.4 2.4 1 1 2 3 3 2 1 Centrosomin N-terminal motif 1 DUF4200 PF13863.6 CDO73255.1 - 0.0026 18.1 26.8 0.0049 17.3 8.4 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4200) KLRAQ PF10205.9 CDO73255.1 - 0.0034 17.6 12.9 0.0046 17.2 5.8 2.3 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein ERM PF00769.19 CDO73255.1 - 0.0039 17.0 28.1 0.0044 16.9 28.1 1.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF5082 PF16888.5 CDO73255.1 - 0.004 17.4 12.9 0.065 13.5 12.7 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) CENP-F_leu_zip PF10473.9 CDO73255.1 - 0.0048 16.9 23.2 0.13 12.3 24.2 2.0 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 CDO73255.1 - 0.0053 15.0 17.4 0.02 13.1 17.4 1.8 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Laminin_II PF06009.12 CDO73255.1 - 0.006 16.6 10.2 0.012 15.6 9.1 1.8 1 1 1 2 2 2 1 Laminin Domain II KELK PF15796.5 CDO73255.1 - 0.0065 16.9 6.4 0.0065 16.9 6.4 3.0 1 1 2 3 3 3 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF812 PF05667.11 CDO73255.1 - 0.0089 15.0 19.8 0.01 14.8 19.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ATG16 PF08614.11 CDO73255.1 - 0.012 15.9 25.9 0.12 12.5 9.3 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Leu_zip PF15294.6 CDO73255.1 - 0.019 14.5 13.2 0.018 14.5 12.3 1.3 1 1 0 1 1 1 0 Leucine zipper DUF2353 PF09789.9 CDO73255.1 - 0.02 14.3 17.9 0.022 14.2 17.9 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF1664 PF07889.12 CDO73255.1 - 0.023 14.7 8.0 0.046 13.8 4.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FliD_C PF07195.12 CDO73255.1 - 0.024 14.0 7.9 0.056 12.9 1.6 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Uso1_p115_C PF04871.13 CDO73255.1 - 0.027 14.9 24.6 0.052 13.9 14.2 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.8 CDO73255.1 - 0.031 13.6 19.9 0.022 14.1 10.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 CDO73255.1 - 0.033 14.2 26.4 0.5 10.4 17.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 CDO73255.1 - 0.035 14.1 22.1 0.16 11.9 7.4 3.0 1 1 1 2 2 2 0 Prefoldin subunit APG17 PF04108.12 CDO73255.1 - 0.043 12.9 11.4 0.3 10.2 4.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg17 SHE3 PF17078.5 CDO73255.1 - 0.045 13.5 15.8 0.055 13.2 15.8 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 CDO73255.1 - 0.046 14.0 13.6 0.6 10.4 2.1 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 CDO73255.1 - 0.085 13.4 30.2 0.34 11.4 30.2 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region HOOK PF05622.12 CDO73255.1 - 0.085 11.0 20.5 0.093 10.9 20.5 1.0 1 0 0 1 1 1 0 HOOK protein TMPIT PF07851.13 CDO73255.1 - 0.088 12.0 9.6 0.1 11.8 9.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein IFT57 PF10498.9 CDO73255.1 - 0.1 11.5 13.7 0.19 10.7 13.7 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 CLZ PF16526.5 CDO73255.1 - 0.11 12.9 18.3 2.2 8.7 6.4 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin_2 PF14523.6 CDO73255.1 - 0.16 12.3 8.9 0.18 12.2 8.3 1.3 1 1 0 1 1 1 0 Syntaxin-like protein DUF730 PF05325.11 CDO73255.1 - 0.16 12.0 11.3 1.6 8.8 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF730) HMMR_C PF15908.5 CDO73255.1 - 0.18 12.1 14.8 0.077 13.3 4.9 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal GrpE PF01025.19 CDO73255.1 - 0.18 11.5 24.1 0.3 10.7 5.1 2.9 1 1 2 3 3 3 0 GrpE Lectin_N PF03954.14 CDO73255.1 - 0.18 11.5 4.6 0.33 10.7 0.8 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Cir_Bir_Yir PF06022.11 CDO73255.1 - 0.18 11.2 1.9 0.22 11.0 1.9 1.0 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Ax_dynein_light PF10211.9 CDO73255.1 - 0.22 11.5 21.6 1 9.3 4.4 2.3 1 1 0 2 2 2 0 Axonemal dynein light chain FPP PF05911.11 CDO73255.1 - 0.25 9.5 17.2 0.28 9.3 17.2 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil WXG100 PF06013.12 CDO73255.1 - 0.26 11.5 7.9 0.91 9.8 0.2 3.0 1 1 0 2 2 2 0 Proteins of 100 residues with WXG UPF0242 PF06785.11 CDO73255.1 - 0.27 11.3 22.0 0.11 12.6 11.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YscO PF07321.12 CDO73255.1 - 0.29 11.1 26.8 0.044 13.7 16.1 2.2 1 1 1 2 2 2 0 Type III secretion protein YscO DUF4337 PF14235.6 CDO73255.1 - 0.29 11.3 21.6 0.15 12.2 7.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF5631 PF18645.1 CDO73255.1 - 0.32 11.4 2.3 1 9.8 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5631) TMF_DNA_bd PF12329.8 CDO73255.1 - 0.32 11.0 22.4 3.7 7.6 15.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Swi5 PF07061.11 CDO73255.1 - 0.35 11.0 19.2 0.58 10.3 0.9 3.0 1 1 2 3 3 3 0 Swi5 Mod_r PF07200.13 CDO73255.1 - 0.39 10.8 20.5 0.28 11.3 12.4 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4407 PF14362.6 CDO73255.1 - 0.44 9.8 16.2 0.86 8.9 16.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Herpes_UL6 PF01763.16 CDO73255.1 - 0.47 8.9 7.6 0.31 9.5 3.5 1.9 1 1 1 2 2 2 0 Herpesvirus UL6 like Rho_Binding PF08912.11 CDO73255.1 - 0.49 11.3 19.8 1.4 9.8 3.6 3.0 1 1 2 3 3 3 0 Rho Binding AAA_13 PF13166.6 CDO73255.1 - 0.5 9.0 12.4 0.78 8.3 12.4 1.3 1 0 0 1 1 1 0 AAA domain PEARLI-4 PF05278.12 CDO73255.1 - 0.51 9.9 13.1 0.64 9.6 13.1 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF948 PF06103.11 CDO73255.1 - 0.66 10.3 3.1 9.4 6.6 0.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.21 CDO73255.1 - 0.7 10.0 17.1 0.24 11.5 4.7 3.2 1 1 3 4 4 4 0 bZIP transcription factor DUF2968 PF11180.8 CDO73255.1 - 0.72 9.5 17.8 0.75 9.4 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Gp-FAR-1 PF05823.12 CDO73255.1 - 0.81 10.0 11.3 1.6 9.0 4.5 2.1 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FlaC_arch PF05377.11 CDO73255.1 - 0.83 10.1 9.4 0.75 10.2 1.4 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 CDO73255.1 - 0.86 9.4 16.9 2.3 8.0 16.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Sec34 PF04136.15 CDO73255.1 - 1.1 9.1 8.1 0.37 10.7 3.0 2.0 1 1 1 2 2 2 0 Sec34-like family THOC7 PF05615.13 CDO73255.1 - 1.2 9.5 21.0 0.39 11.0 9.5 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 Fez1 PF06818.15 CDO73255.1 - 1.2 9.6 20.3 2 8.9 20.3 1.4 1 1 0 1 1 1 0 Fez1 ZapB PF06005.12 CDO73255.1 - 1.2 9.6 25.9 7.7 7.0 8.5 3.2 1 1 1 2 2 2 0 Cell division protein ZapB Rootletin PF15035.6 CDO73255.1 - 1.2 9.1 19.6 0.99 9.4 9.2 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.10 CDO73255.1 - 1.2 9.3 11.7 0.98 9.6 7.5 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TolA_bind_tri PF16331.5 CDO73255.1 - 1.3 9.2 18.6 5.1 7.2 7.1 3.0 1 1 2 3 3 3 0 TolA binding protein trimerisation V_ATPase_I PF01496.19 CDO73255.1 - 1.3 6.9 9.2 1.5 6.7 9.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_CLD_2 PF14197.6 CDO73255.1 - 1.3 9.1 21.8 1.1 9.3 1.5 3.1 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 DUF3584 PF12128.8 CDO73255.1 - 1.4 6.3 21.9 1.6 6.1 21.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4201 PF13870.6 CDO73255.1 - 1.5 8.6 21.3 3 7.5 7.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Spc24 PF08286.11 CDO73255.1 - 1.5 9.1 16.1 1.9 8.8 4.6 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.9 CDO73255.1 - 1.5 7.8 18.9 6.7 5.7 19.0 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BRE1 PF08647.11 CDO73255.1 - 1.5 8.9 21.2 0.86 9.7 8.9 2.4 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DHR10 PF18595.1 CDO73255.1 - 1.6 8.8 27.6 0.31 11.1 12.9 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF4446 PF14584.6 CDO73255.1 - 1.8 8.6 12.3 3 7.8 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) HAUS-augmin3 PF14932.6 CDO73255.1 - 1.8 8.1 16.2 4.2 6.9 16.2 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 bZIP_Maf PF03131.17 CDO73255.1 - 2 9.0 16.8 1.2 9.7 4.7 2.6 1 1 1 2 2 2 0 bZIP Maf transcription factor PI3K_P85_iSH2 PF16454.5 CDO73255.1 - 2.3 7.8 19.1 3.4 7.2 12.2 2.4 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Exonuc_VII_L PF02601.15 CDO73255.1 - 2.7 7.5 10.9 3.3 7.2 10.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fmp27_WPPW PF10359.9 CDO73255.1 - 2.9 6.6 16.2 9.4 5.0 14.9 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain GBP_C PF02841.14 CDO73255.1 - 3 7.2 16.9 5.5 6.3 16.9 1.4 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain LIN37 PF15306.6 CDO73255.1 - 3 8.0 10.2 5.9 7.1 10.2 1.6 1 1 0 1 1 1 0 LIN37 OmpH PF03938.14 CDO73255.1 - 3.5 8.0 22.2 18 5.6 22.2 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF773 PF05600.12 CDO73255.1 - 3.6 6.2 15.9 3.2 6.4 2.2 2.0 1 1 1 2 2 2 0 CDK5 regulatory subunit-associated protein 3 Fzo_mitofusin PF04799.13 CDO73255.1 - 3.8 7.0 8.8 1.5 8.4 4.8 2.1 1 1 2 3 3 3 0 fzo-like conserved region AAA-ATPase_like PF09820.9 CDO73255.1 - 3.9 6.8 7.3 0.66 9.3 1.1 1.9 1 1 1 2 2 2 0 Predicted AAA-ATPase Med21 PF11221.8 CDO73255.1 - 4.4 7.5 20.4 0.33 11.2 7.7 2.6 1 1 2 3 3 3 0 Subunit 21 of Mediator complex FUSC PF04632.12 CDO73255.1 - 4.8 5.6 7.1 5.4 5.4 7.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF16 PF01519.16 CDO73255.1 - 4.8 7.7 13.2 5.8e+02 1.0 13.2 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 Med2 PF11214.8 CDO73255.1 - 6.7 6.9 13.0 9.6 6.4 11.6 2.0 1 1 1 2 2 1 0 Mediator complex subunit 2 FapA PF03961.13 CDO73255.1 - 7 5.1 15.5 5.2 5.6 12.6 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A Nnf1 PF03980.14 CDO73255.1 - 7.6 7.0 18.9 1.1 9.6 4.0 2.5 1 1 1 2 2 2 0 Nnf1 XhlA PF10779.9 CDO73255.1 - 9.3 6.5 21.0 2.2 8.5 4.3 3.0 1 1 2 3 3 3 0 Haemolysin XhlA DUF2203 PF09969.9 CDO73255.1 - 9.3 7.0 15.6 3.1 8.5 5.9 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SelR PF01641.18 CDO73256.1 - 1.1e-49 167.5 0.1 1.3e-49 167.3 0.1 1.0 1 0 0 1 1 1 1 SelR domain GFA PF04828.14 CDO73256.1 - 0.012 15.9 0.5 0.1 13.0 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 CDO73256.1 - 0.045 13.8 2.4 0.33 11.0 2.3 2.1 1 1 1 2 2 2 0 Double zinc ribbon ADD_ATRX PF17981.1 CDO73256.1 - 0.05 13.5 0.0 0.62 10.0 0.0 2.1 2 0 0 2 2 2 0 Cysteine Rich ADD domain Yippee-Mis18 PF03226.14 CDO73256.1 - 0.15 12.3 0.8 1.8 8.8 0.8 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Auto_anti-p27 PF06677.12 CDO73256.1 - 0.18 12.0 1.3 1.2 9.4 0.1 2.5 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-Mss51 PF13824.6 CDO73256.1 - 0.29 11.3 6.5 0.3 11.2 0.2 3.2 2 1 2 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 Ribosomal_L37e PF01907.19 CDO73256.1 - 0.47 10.7 3.5 2.2 8.5 0.5 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e TF_Zn_Ribbon PF08271.12 CDO73256.1 - 2 8.0 5.3 16 5.1 0.4 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 CDO73256.1 - 3.7 7.1 7.2 12 5.5 0.1 3.2 4 0 0 4 4 4 0 zinc-ribbon domain Pkinase PF00069.25 CDO73257.1 - 9.6e-76 254.6 0.0 1.1e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73257.1 - 2.7e-32 112.1 0.0 9.6e-32 110.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO73257.1 - 0.0094 15.3 0.2 0.22 10.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDO73257.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO73257.1 - 0.026 13.5 0.0 0.28 10.1 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain zf-RanBP PF00641.18 CDO73258.1 - 6.6e-12 44.5 11.4 3.1e-06 26.4 2.4 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 CDO73258.1 - 2.3e-05 23.7 1.6 0.22 10.9 0.0 2.8 2 0 0 2 2 2 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 CDO73258.1 - 0.041 14.0 0.5 11 6.1 0.1 2.9 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger C1_2 PF03107.16 CDO73258.1 - 0.34 11.3 1.9 19 5.7 0.1 2.5 2 0 0 2 2 2 0 C1 domain ERK-JNK_inhib PF15002.6 CDO73258.1 - 0.55 9.9 4.5 0.96 9.1 4.5 1.3 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor NADH-u_ox-rdase PF10785.9 CDO73259.1 - 1.4e-32 112.2 0.0 1.9e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 CDO73259.1 - 1.4e-12 47.4 0.0 2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit ANAPC4_WD40 PF12894.7 CDO73260.1 - 0.0022 18.3 0.1 0.0048 17.2 0.0 1.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4349 PF14257.6 CDO73260.1 - 0.038 13.4 0.1 0.073 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1192 PF06698.11 CDO73260.1 - 0.051 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) PKcGMP_CC PF16808.5 CDO73260.1 - 0.086 12.7 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_2 PF07716.15 CDO73260.1 - 0.54 10.4 0.2 0.54 10.4 0.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DnaJ PF00226.31 CDO73261.1 - 4.7e-14 52.3 1.2 1.1e-13 51.0 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain DDE_3 PF13358.6 CDO73261.1 - 9.2e-08 32.0 0.2 0.00069 19.4 0.1 2.8 2 0 0 2 2 2 2 DDE superfamily endonuclease SH3_1 PF00018.28 CDO73262.1 - 1.1e-17 63.3 2.5 2.7e-08 33.3 0.1 3.2 2 1 0 2 2 2 2 SH3 domain SAM_2 PF07647.17 CDO73262.1 - 7.4e-14 51.6 0.0 1.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 CDO73262.1 - 6.7e-13 48.3 1.3 3.8e-06 26.6 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain SAM_1 PF00536.30 CDO73262.1 - 7.8e-12 45.5 0.0 1.6e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 CDO73262.1 - 7.1e-08 32.0 0.2 2.6e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.23 CDO73262.1 - 2.6e-07 31.2 0.0 5.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.11 CDO73262.1 - 0.0096 16.2 3.0 0.88 9.9 0.3 2.8 2 0 0 2 2 2 2 Bacterial SH3 domain SAM_3 PF18016.1 CDO73262.1 - 0.073 12.9 0.1 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) aGPT-Pplase1 PF18723.1 CDO73264.1 - 1.1e-102 343.3 0.0 1.4e-102 343.0 0.0 1.1 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 CDO73264.1 - 2.7e-12 46.4 0.2 6.3e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DnaJ PF00226.31 CDO73265.1 - 1.8e-20 72.8 0.5 3.8e-20 71.8 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain ThiS PF02597.20 CDO73265.1 - 0.076 13.7 2.0 1.8 9.3 0.0 3.2 2 2 1 3 3 3 0 ThiS family Bac_small_YrzI PF09501.10 CDO73265.1 - 0.49 10.6 6.0 1.5 9.0 0.9 2.6 1 1 1 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) DUF4407 PF14362.6 CDO73265.1 - 6.2 6.1 15.7 1.3 8.3 12.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) OHCU_decarbox PF09349.10 CDO73266.1 - 1.2e-33 116.8 0.0 1.7e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase CTP_transf_like PF01467.26 CDO73267.1 - 1.1e-09 38.6 0.0 1.8e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like zf-C2H2 PF00096.26 CDO73268.1 - 2.9e-19 68.3 20.5 0.00038 20.8 0.7 7.2 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO73268.1 - 1.3e-17 63.3 24.0 8.9e-06 25.9 0.2 5.8 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDO73268.1 - 3.9e-11 42.8 35.7 0.0034 18.1 0.4 7.6 7 0 0 7 7 6 3 C2H2-type zinc finger FOXP-CC PF16159.5 CDO73268.1 - 1.4e-06 28.8 17.1 0.06 14.0 1.9 5.8 3 1 2 5 5 5 2 FOXP coiled-coil domain zf_ZIC PF18366.1 CDO73268.1 - 0.0005 20.1 0.7 3.6 7.8 0.0 4.9 4 0 0 4 4 4 1 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 CDO73268.1 - 0.0006 20.0 2.5 0.043 14.1 0.2 3.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CDO73268.1 - 0.0043 17.0 16.2 11 6.1 0.7 5.8 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDO73268.1 - 0.011 15.5 13.8 1.6 8.6 0.0 5.5 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 CDO73268.1 - 0.029 14.1 10.5 0.44 10.4 1.5 4.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 CDO73268.1 - 0.12 12.9 6.0 4.2 7.9 0.3 2.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 CDO73268.1 - 0.12 12.7 11.5 0.88 9.9 4.3 4.2 3 1 2 5 5 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 CDO73268.1 - 8.2 6.4 8.8 6.6 6.7 0.1 3.8 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) Peptidase_M20 PF01546.28 CDO73269.1 - 9.7e-26 90.7 0.0 5.1e-25 88.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDO73269.1 - 6e-15 55.1 0.0 2.1e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain M20_dimer PF07687.14 CDO73270.1 - 5e-10 39.3 0.2 9.9e-10 38.3 0.2 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain SLC35F PF06027.12 CDO73272.1 - 3.3e-99 332.2 16.4 4.4e-99 331.8 16.4 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 CDO73272.1 - 1.1e-09 37.7 0.2 2.8e-09 36.4 0.2 1.6 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like RRM_1 PF00076.22 CDO73273.1 - 2e-26 91.6 0.7 1.2e-14 53.9 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDO73273.1 - 2.6e-06 27.4 0.0 0.0031 17.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 CDO73273.1 - 0.012 15.5 0.0 0.69 9.8 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif TcpA PF05946.12 CDO73273.1 - 0.017 15.2 0.7 0.44 10.7 0.0 2.3 2 0 0 2 2 2 0 Toxin-coregulated pilus subunit TcpA Amidase PF01425.21 CDO73274.1 - 5.9e-71 239.8 0.0 1e-46 159.8 0.0 3.5 1 1 2 3 3 3 3 Amidase Fis1_TPR_C PF14853.6 CDO73275.1 - 2.4e-23 82.0 0.4 3.9e-23 81.3 0.4 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CDO73275.1 - 5.2e-13 48.4 0.0 8.9e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 CDO73275.1 - 0.00018 21.3 0.4 0.00047 20.1 0.4 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDO73275.1 - 0.021 15.4 0.1 0.048 14.3 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDO73275.1 - 0.027 14.3 1.1 0.061 13.2 1.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDO73275.1 - 0.032 14.8 0.2 0.07 13.6 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO73275.1 - 0.052 13.8 0.1 0.079 13.2 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDO73275.1 - 0.064 13.3 0.2 0.16 12.0 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_M50B PF13398.6 CDO73276.1 - 8.3e-46 156.1 16.7 1.1e-45 155.8 16.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like VPDSG-CTERM PF18205.1 CDO73276.1 - 0.053 13.3 0.8 0.3 10.9 0.8 2.4 1 0 0 1 1 1 0 VPDSG-CTERM motif Histone PF00125.24 CDO73277.1 - 9.9e-18 64.8 0.0 1.3e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDO73277.1 - 6.6e-17 61.0 0.8 1.3e-16 60.1 0.8 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CDO73277.1 - 1.4e-06 28.5 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_60s PF00428.19 CDO73278.1 - 2.3e-26 92.2 10.3 2.8e-26 91.9 10.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 CDO73278.1 - 0.0046 17.3 0.2 0.0075 16.6 0.0 1.4 2 0 0 2 2 2 1 EF-hand domain DUF3824 PF12868.7 CDO73278.1 - 0.09 13.4 1.3 0.12 13.0 1.3 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ribosomal_S19 PF00203.21 CDO73279.1 - 9.1e-35 118.4 0.3 1.4e-34 117.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 CDO73279.1 - 0.003 17.6 0.0 0.0036 17.4 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH RhoGAP PF00620.27 CDO73280.1 - 1.1e-35 122.7 0.1 2.1e-35 121.8 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 CDO73280.1 - 2.5e-28 98.1 38.1 8.7e-11 41.9 0.8 4.6 4 0 0 4 4 4 4 LIM domain Peptidase_M20 PF01546.28 CDO73281.1 - 4.9e-35 121.1 0.0 9e-35 120.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDO73281.1 - 7.9e-12 45.1 0.1 2.6e-11 43.4 0.1 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CDO73281.1 - 6.7e-06 25.9 0.0 2.6e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M28 Ribonucleas_3_3 PF14622.6 CDO73282.1 - 3.6e-09 36.9 0.0 8.9e-09 35.6 0.0 1.6 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 CDO73282.1 - 2.5e-06 28.1 0.0 7.9e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 CDO73282.1 - 4.5e-05 24.0 0.0 9.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain RhoGAP PF00620.27 CDO73283.1 - 4.2e-10 39.6 0.1 1.2e-09 38.2 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 CDO73283.1 - 2.2e-06 27.6 0.0 5.3e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Tipalpha PF16753.5 CDO73283.1 - 0.15 11.9 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 TNF-alpha-Inducing protein of Helicobacter Fib_alpha PF08702.10 CDO73283.1 - 4.9 7.3 6.1 46 4.2 0.9 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Zn_clus PF00172.18 CDO73284.1 - 1.4e-09 37.9 10.3 2.9e-09 36.9 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CDO73284.1 - 2.5e-08 33.3 0.9 4.4e-08 32.5 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain V-ATPase_G PF03179.15 CDO73285.1 - 2e-32 111.8 20.3 2.3e-32 111.6 20.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 CDO73285.1 - 0.026 14.6 13.3 0.026 14.6 13.3 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) NCKAP5 PF15246.6 CDO73285.1 - 0.068 12.8 8.9 0.082 12.5 8.9 1.0 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein S_layer_C PF05124.12 CDO73285.1 - 0.14 12.1 4.3 0.16 12.0 4.3 1.0 1 0 0 1 1 1 0 S-layer like family, C-terminal region Muted PF14942.6 CDO73285.1 - 0.58 10.5 13.9 1.3 9.4 12.6 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein V-ATPase_G_2 PF16999.5 CDO73285.1 - 0.68 10.4 20.8 1.3 9.4 20.8 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit TarH PF02203.15 CDO73285.1 - 1.8 8.5 12.1 2.2 8.2 12.1 1.1 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF16 PF01519.16 CDO73285.1 - 6.2 7.4 10.6 0.62 10.6 5.5 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Symplekin_C PF12295.8 CDO73286.1 - 1e-61 208.3 0.3 2.5e-61 207.1 0.3 1.7 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 CDO73286.1 - 1.3e-49 168.9 0.6 2.4e-49 168.0 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) DUF913 PF06025.12 CDO73286.1 - 0.00021 20.4 1.1 0.012 14.6 0.1 2.5 2 0 0 2 2 2 2 Domain of Unknown Function (DUF913) V-ATPase_H_N PF03224.14 CDO73286.1 - 0.2 10.9 0.7 9.6 5.4 0.7 2.6 3 0 0 3 3 3 0 V-ATPase subunit H RNA_pol_Rpc4 PF05132.14 CDO73287.1 - 1e-35 123.3 0.3 1e-35 123.3 0.3 3.1 2 1 0 2 2 2 1 RNA polymerase III RPC4 SL4P PF17618.2 CDO73288.1 - 0.022 14.8 0.1 0.093 12.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein HET PF06985.11 CDO73289.1 - 2.1e-11 44.4 2.4 6.5e-08 33.0 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Mito_carr PF00153.27 CDO73290.1 - 8.6e-48 160.2 1.5 1.5e-22 79.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rick_17kDa_Anti PF05433.15 CDO73290.1 - 0.56 10.1 9.6 2.9 7.8 4.7 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain TFIID_30kDa PF03540.13 CDO73291.1 - 1.2e-25 89.1 0.0 1.9e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 CDO73291.1 - 0.021 14.8 0.0 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated Ribosomal_60s PF00428.19 CDO73291.1 - 0.023 15.3 0.0 0.023 15.3 0.0 2.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein FoP_duplication PF13865.6 CDO73291.1 - 0.064 13.8 0.9 0.19 12.3 0.2 1.9 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF3464 PF11947.8 CDO73291.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CCDC53 PF10152.9 CDO73291.1 - 0.79 10.1 4.2 0.36 11.2 1.8 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex GFO_IDH_MocA PF01408.22 CDO73292.1 - 3.4e-19 69.8 0.1 5.9e-19 69.1 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CTNNB1_binding PF08347.11 CDO73293.1 - 0.0018 18.5 0.6 0.0036 17.5 0.6 1.5 1 0 0 1 1 1 1 N-terminal CTNNB1 binding DUF5380 PF17351.2 CDO73293.1 - 0.064 13.1 0.0 3 7.8 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5380) zf-CCCH PF00642.24 CDO73293.1 - 0.24 11.3 4.3 0.5 10.3 4.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CDO73293.1 - 6.7 7.4 6.9 12 6.5 6.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Pkinase PF00069.25 CDO73294.1 - 6e-55 186.5 0.0 7.8e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73294.1 - 4.3e-33 114.7 0.0 5.6e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDO73294.1 - 0.0078 15.2 0.1 0.01 14.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDO73294.1 - 0.021 14.7 0.1 0.053 13.4 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CDO73294.1 - 0.026 13.9 0.2 0.053 12.9 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_5 PF17121.5 CDO73294.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 CDO73295.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ParA PF10609.9 CDO73296.1 - 9.4e-97 323.3 0.0 1.1e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CDO73296.1 - 2.1e-08 34.2 0.0 3.6e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CDO73296.1 - 4.6e-05 22.7 1.4 0.0022 17.2 0.1 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 CDO73296.1 - 0.00019 21.4 0.1 0.0015 18.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 CDO73296.1 - 0.002 17.6 0.0 0.0071 15.9 0.0 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 CDO73296.1 - 0.012 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 CDO73296.1 - 0.019 14.4 0.0 1.2 8.6 0.0 2.5 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 CDO73296.1 - 0.02 14.8 0.1 0.045 13.7 0.1 1.5 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 CDO73296.1 - 0.045 12.9 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain TF_Zn_Ribbon PF08271.12 CDO73296.1 - 0.1 12.1 0.2 0.21 11.1 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding VirE PF05272.11 CDO73296.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Zn_Tnp_IS1595 PF12760.7 CDO73296.1 - 0.5 10.4 0.1 0.5 10.4 0.1 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain WD40 PF00400.32 CDO73297.1 - 3.5e-15 56.1 2.8 1.1e-05 26.1 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO73297.1 - 1.8e-07 31.4 0.0 5.1 7.5 0.0 5.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SCA7 PF08313.12 CDO73298.1 - 2.5e-30 104.2 0.1 7.1e-30 102.7 0.1 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain zf_C2H2_13 PF18508.1 CDO73298.1 - 0.0091 15.6 0.3 0.017 14.7 0.3 1.4 1 0 0 1 1 1 1 Zinc finger domain Jak1_Phl PF17887.1 CDO73298.1 - 1 9.3 3.4 1.2 9.1 0.3 2.1 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain MAS20 PF02064.15 CDO73298.1 - 7.2 6.7 8.0 0.31 11.1 1.6 1.9 2 0 0 2 2 2 0 MAS20 protein import receptor hDGE_amylase PF14701.6 CDO73299.1 - 3.1e-161 537.4 0.0 4e-161 537.0 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CDO73299.1 - 3.9e-122 407.9 0.0 5.3e-122 407.5 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CDO73299.1 - 2.8e-79 266.3 0.0 4e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CDO73299.1 - 7.2e-22 77.3 0.0 1.5e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Uricase PF01014.18 CDO73301.1 - 6.3e-64 214.1 0.1 1.1e-30 106.5 0.2 2.0 2 0 0 2 2 2 2 Uricase zf_CCCH_4 PF18345.1 CDO73302.1 - 2.8e-16 58.9 43.9 4.2e-05 23.5 5.9 4.6 4 0 0 4 4 4 4 Zinc finger domain Torus PF16131.5 CDO73302.1 - 1.2e-15 58.2 6.8 0.001 19.7 0.2 4.8 5 0 0 5 5 5 4 Torus domain zf-CCCH PF00642.24 CDO73302.1 - 1e-11 44.5 38.5 8.7e-05 22.3 6.1 4.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 CDO73302.1 - 1.3e-10 40.9 0.0 0.0022 17.8 0.0 4.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IBR PF01485.21 CDO73302.1 - 3.6e-09 36.7 3.9 3.6e-09 36.7 3.9 2.6 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 CDO73302.1 - 8.1e-09 35.4 5.2 2.4e-08 33.9 5.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDO73302.1 - 5.2e-07 29.4 2.7 5.2e-07 29.4 2.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 CDO73302.1 - 3.5e-05 23.5 38.4 0.086 12.7 2.9 4.6 4 0 0 4 4 4 3 CCCH-type zinc finger zf-C3HC4_3 PF13920.6 CDO73302.1 - 4.3e-05 23.3 4.1 4.3e-05 23.3 4.1 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO73302.1 - 7.4e-05 23.0 5.0 7.4e-05 23.0 5.0 3.3 2 0 0 2 2 2 1 Ring finger domain zf-CCCH_3 PF15663.5 CDO73302.1 - 9.5e-05 22.6 23.0 0.086 13.1 0.1 5.1 4 1 0 5 5 5 3 Zinc-finger containing family zf-C3HC4_2 PF13923.6 CDO73302.1 - 0.0001 22.1 4.6 0.0001 22.1 4.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO73302.1 - 0.00026 20.9 4.2 0.00026 20.9 4.2 2.2 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDO73302.1 - 0.00059 19.9 7.6 0.00059 19.9 7.6 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 CDO73302.1 - 0.021 15.3 48.6 0.056 13.9 6.2 5.2 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger Pkinase PF00069.25 CDO73303.1 - 2.4e-69 233.6 0.0 3.5e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73303.1 - 8.2e-37 126.9 0.0 1.4e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO73303.1 - 7.6e-06 25.4 0.0 0.0001 21.7 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 CDO73303.1 - 0.0079 15.2 0.1 0.013 14.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDO73303.1 - 0.043 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO73303.1 - 0.93 9.4 13.8 0.14 12.1 0.4 3.6 4 0 0 4 4 4 0 Phosphotransferase enzyme family Tma16 PF11176.8 CDO73304.1 - 2e-30 105.6 17.6 2e-23 82.9 2.7 2.8 2 1 1 3 3 3 2 Translation machinery-associated protein 16 Sigma70_r1_2 PF00140.20 CDO73304.1 - 0.017 15.1 0.1 0.054 13.5 0.1 1.9 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 DUF2058 PF09831.9 CDO73304.1 - 3.9 7.6 13.6 0.85 9.8 9.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) PAT1 PF09770.9 CDO73306.1 - 1.7e-108 364.1 59.1 8.6e-87 292.3 33.8 3.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Pertussis_S1 PF02917.14 CDO73306.1 - 0.61 9.8 2.6 2.3 7.9 0.4 2.2 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 DNA_ligase_A_M PF01068.21 CDO73307.1 - 5.9e-51 173.0 0.0 9.9e-51 172.3 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CDO73307.1 - 1.2e-35 123.4 0.0 2.6e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 CDO73307.1 - 8.5e-22 77.4 0.0 2.3e-10 40.7 0.0 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 CDO73307.1 - 1.7e-15 57.4 0.1 2.9e-14 53.5 0.0 2.7 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CDO73307.1 - 1.3e-11 45.1 0.0 2.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 CDO73307.1 - 5e-08 33.2 0.2 0.0035 17.7 0.0 3.3 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CDO73307.1 - 0.002 18.4 0.1 0.064 13.6 0.0 2.6 2 1 0 2 2 2 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 CDO73307.1 - 0.065 13.2 0.0 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 twin BRCT domain Forkhead PF00250.18 CDO73308.1 - 2.3e-24 85.4 0.0 4e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Adaptin_N PF01602.20 CDO73309.1 - 1.7e-143 479.0 6.2 1.9e-143 478.8 6.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CDO73309.1 - 6.8e-25 87.5 0.0 1.7e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CDO73309.1 - 1.1e-08 35.2 5.0 8.5e-07 29.1 0.1 3.6 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDO73309.1 - 0.004 17.5 3.1 1.6 9.2 0.2 4.5 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 CDO73309.1 - 0.028 14.7 1.8 1e+02 3.6 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat SF3b1 PF08920.10 CDO73310.1 - 6.4e-20 71.8 3.4 1.9e-19 70.3 3.4 1.9 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 CDO73310.1 - 3.1e-10 40.3 16.7 0.0015 18.9 0.1 7.9 5 2 4 9 9 9 4 HEAT repeats HEAT_EZ PF13513.6 CDO73310.1 - 1.8e-09 37.9 12.0 0.0018 18.7 0.0 7.9 9 1 1 10 10 10 3 HEAT-like repeat HEAT PF02985.22 CDO73310.1 - 1.3e-08 34.4 11.8 0.01 16.0 0.1 9.4 12 0 0 12 12 9 1 HEAT repeat Adaptin_N PF01602.20 CDO73310.1 - 3.2e-07 29.3 3.4 0.0037 15.9 0.1 3.4 2 1 0 3 3 3 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 CDO73310.1 - 3.8e-07 30.6 1.2 0.44 11.2 0.0 5.4 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CDO73310.1 - 2.2e-06 27.8 9.4 0.37 10.8 0.0 6.6 8 0 0 8 8 8 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CDO73310.1 - 3.3e-05 23.5 1.1 0.32 10.5 0.0 3.9 3 1 0 3 3 3 2 CLASP N terminal NUC173 PF08161.12 CDO73310.1 - 4.4e-05 23.2 1.4 1.5 8.4 0.0 5.1 4 1 1 5 5 5 2 NUC173 domain UME PF08064.13 CDO73310.1 - 0.00021 21.2 0.2 0.36 10.8 0.0 4.6 3 2 1 4 4 4 1 UME (NUC010) domain MMS19_C PF12460.8 CDO73310.1 - 0.001 18.3 0.1 4.5 6.3 0.0 4.3 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal DUF3110 PF11360.8 CDO73310.1 - 0.026 14.7 0.1 0.099 12.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Dopey_N PF04118.14 CDO73310.1 - 0.028 13.5 1.7 1.2 8.1 0.0 3.7 4 1 0 4 4 4 0 Dopey, N-terminal DUF3385 PF11865.8 CDO73310.1 - 0.094 12.6 6.3 1.8 8.5 0.1 5.0 5 2 1 6 6 6 0 Domain of unknown function (DUF3385) NMO PF03060.15 CDO73311.1 - 7.1e-48 163.7 0.1 1e-47 163.2 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CDO73311.1 - 1.3e-07 30.9 1.1 5.2e-07 29.0 1.1 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CDO73311.1 - 0.004 16.2 2.1 0.0058 15.7 2.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PACT_coil_coil PF10495.9 CDO73312.1 - 2.4e-13 50.4 0.1 2.4e-13 50.4 0.1 4.9 5 1 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein HMMR_N PF15905.5 CDO73312.1 - 0.0027 17.3 15.8 0.0027 17.3 15.8 7.3 2 2 4 6 6 6 2 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 CDO73312.1 - 0.011 16.3 23.7 0.011 16.3 23.7 7.8 3 2 3 7 7 7 0 Fez1 Zn_ribbon_SprT PF17283.2 CDO73312.1 - 5.2 7.1 6.3 10 6.1 6.3 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain DUF1752 PF08550.10 CDO73314.1 - 1.4e-08 34.4 9.6 3.5e-08 33.1 9.6 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) BTB PF00651.31 CDO73315.1 - 4.1e-10 39.9 0.0 4.3e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DNA_binding_2 PF13724.6 CDO73315.1 - 0.29 11.6 1.1 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 DNA-binding domain BTB PF00651.31 CDO73316.1 - 1.5e-11 44.5 0.0 7.8e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain VPS9 PF02204.18 CDO73317.1 - 1.6e-32 111.8 0.2 3.8e-32 110.6 0.1 1.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CDO73317.1 - 7.3e-19 67.8 0.6 2e-18 66.4 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 CDO73317.1 - 3.7e-10 39.3 0.0 1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 CDO73317.1 - 0.00012 21.5 0.0 0.00039 19.9 0.0 1.9 2 0 0 2 2 2 1 DMRTA motif SNARE PF05739.19 CDO73317.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 SNARE domain BTB PF00651.31 CDO73318.1 - 3.3e-24 85.3 0.0 1.1e-05 25.7 0.0 5.0 5 0 0 5 5 5 3 BTB/POZ domain Methyltransf_11 PF08241.12 CDO73318.1 - 0.018 15.7 0.7 7.7 7.2 0.0 3.7 3 0 0 3 3 3 0 Methyltransferase domain HMG_CoA_synt_C PF08540.10 CDO73319.1 - 1.6e-91 306.8 0.2 2.2e-91 306.4 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 CDO73319.1 - 1.7e-83 278.7 0.1 3.1e-83 277.9 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 CDO73319.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 CDO73319.1 - 0.1 12.8 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal BTB PF00651.31 CDO73320.1 - 2.3e-06 27.8 0.0 0.00033 20.8 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 CDO73321.1 - 1.6e-21 76.6 0.0 3.7e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Skp1_POZ PF03931.15 CDO73321.1 - 0.069 13.3 0.0 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Solute_trans_a PF03619.16 CDO73322.1 - 2.2e-69 233.9 16.7 8.6e-54 182.8 5.5 2.1 1 1 1 2 2 2 2 Organic solute transporter Ostalpha An_peroxidase PF03098.15 CDO73323.1 - 6.1e-13 48.2 0.4 9.4e-07 27.8 0.0 3.3 1 1 2 3 3 3 3 Animal haem peroxidase Coatomer_E PF04733.14 CDO73324.1 - 2.8e-32 112.3 0.1 9.7e-32 110.5 0.1 1.7 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 CDO73324.1 - 0.0032 17.4 3.4 11 6.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDO73324.1 - 0.0033 17.5 0.4 0.0033 17.5 0.4 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDO73324.1 - 0.041 14.1 0.5 1.6 9.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDO73324.1 - 1.9 9.1 16.2 5.6 7.6 0.3 5.2 2 2 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDO73324.1 - 6.8 7.6 11.6 71 4.4 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DZR PF12773.7 CDO73325.1 - 0.27 11.3 3.6 0.55 10.3 3.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon Rad9 PF04139.13 CDO73327.1 - 8.5e-32 110.6 0.0 1.8e-31 109.5 0.0 1.5 1 1 0 1 1 1 1 Rad9 Pkinase PF00069.25 CDO73328.1 - 9.5e-75 251.4 0.0 1.3e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73328.1 - 6.1e-51 173.2 0.0 9.7e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CDO73328.1 - 5.5e-23 81.1 0.1 1.2e-22 80.0 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 CDO73328.1 - 1.4e-05 24.1 0.1 2.4e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDO73328.1 - 0.00069 19.0 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDO73328.1 - 0.0048 16.3 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO73328.1 - 0.014 15.3 0.3 0.26 11.2 0.3 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.12 CDO73328.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain PIF1 PF05970.14 CDO73329.1 - 3e-62 210.9 0.6 1.2e-46 159.5 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CDO73329.1 - 2.8e-22 79.4 0.0 4.7e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDO73329.1 - 2.2e-11 44.3 0.0 4.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CDO73329.1 - 1.2e-06 26.8 0.2 4.5e-05 21.6 0.0 2.2 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 CDO73329.1 - 0.00019 21.3 0.3 0.28 10.9 0.1 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CDO73329.1 - 0.00021 21.6 0.0 0.00064 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CDO73329.1 - 0.00024 20.8 0.0 0.00071 19.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 CDO73329.1 - 0.0061 16.9 0.3 0.017 15.5 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain SH3_13 PF18335.1 CDO73329.1 - 0.019 14.8 0.0 0.057 13.2 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain NACHT PF05729.12 CDO73329.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 CDO73329.1 - 0.04 14.3 0.1 0.1 13.0 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CDO73329.1 - 0.054 13.5 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF5605 PF18310.1 CDO73329.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) DUF2075 PF09848.9 CDO73329.1 - 0.058 12.6 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 CDO73329.1 - 0.067 12.2 0.1 0.14 11.1 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 CDO73329.1 - 0.07 12.6 0.1 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CDO73329.1 - 0.11 12.3 0.9 1.4 8.8 0.9 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 CDO73329.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Muraidase PF11860.8 CDO73329.1 - 0.16 12.2 0.2 0.38 11.0 0.0 1.7 2 0 0 2 2 1 0 N-acetylmuramidase MaoC_dehydrat_N PF13452.6 CDO73329.1 - 0.17 12.0 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase ABC_tran PF00005.27 CDO73329.1 - 0.24 11.9 1.0 0.98 9.9 0.1 2.4 2 1 0 2 2 2 0 ABC transporter TMF_DNA_bd PF12329.8 CDO73329.1 - 5.6 7.0 5.6 13 5.9 0.6 2.6 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding PI3_PI4_kinase PF00454.27 CDO73330.1 - 1.9e-52 178.5 0.0 4.7e-52 177.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 CDO73330.1 - 1.7e-18 67.2 0.2 1.3e-17 64.3 0.0 2.8 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 CDO73330.1 - 3.5e-12 45.9 0.2 9.1e-12 44.6 0.2 1.8 1 0 0 1 1 1 1 FATC domain F-box-like PF12937.7 CDO73331.1 - 1.2e-13 50.7 1.4 4e-13 49.0 1.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO73331.1 - 0.0016 18.3 0.8 0.013 15.4 0.3 2.9 2 1 0 2 2 2 1 F-box domain Med6 PF04934.14 CDO73331.1 - 0.0058 16.4 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component LRR_4 PF12799.7 CDO73331.1 - 0.066 13.7 1.4 41 4.8 0.1 4.7 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like_2 PF13013.6 CDO73331.1 - 0.14 12.1 0.1 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain LRR_8 PF13855.6 CDO73331.1 - 0.15 11.8 3.0 31 4.4 0.3 4.0 4 0 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 CDO73332.1 - 1.1e-13 50.8 1.9 5.2e-13 48.7 1.4 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDO73332.1 - 0.00045 20.0 4.5 0.0027 17.5 0.1 3.9 4 0 0 4 4 4 1 F-box domain Peptidase_M74 PF03411.13 CDO73332.1 - 0.14 11.6 0.2 14 5.2 0.4 2.8 2 1 1 3 3 3 0 Penicillin-insensitive murein endopeptidase RNA_pol_Rpb4 PF03874.16 CDO73333.1 - 1.5e-20 73.7 1.2 3.9e-20 72.4 1.2 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 Aa_trans PF01490.18 CDO73334.1 - 1.1e-72 245.0 21.9 1.5e-72 244.6 21.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SUZ PF12752.7 CDO73335.1 - 2.3e-15 57.1 2.7 2.3e-15 57.1 2.7 4.9 3 2 0 3 3 3 1 SUZ domain R3H PF01424.22 CDO73335.1 - 0.00016 21.6 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 R3H domain BTB PF00651.31 CDO73336.1 - 0.00012 22.3 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF4609 PF15382.6 CDO73337.1 - 0.018 14.9 0.1 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) CheR PF01739.18 CDO73338.1 - 0.14 11.6 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF4218 PF13960.6 CDO73340.1 - 0.013 15.1 0.2 0.028 14.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Voldacs PF03517.13 CDO73341.1 - 0.1 12.7 0.1 0.98 9.5 0.0 2.4 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling CCDC-167 PF15188.6 CDO73341.1 - 0.77 10.1 4.6 0.77 10.1 2.8 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 BTB PF00651.31 CDO73343.1 - 2.6e-11 43.7 0.1 3.6e-05 24.0 0.0 3.2 2 1 0 2 2 2 2 BTB/POZ domain FGGY_N PF00370.21 CDO73344.1 - 1.9e-23 83.3 0.0 6.8e-16 58.6 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CDO73344.1 - 3.9e-19 69.2 0.0 2.4e-18 66.6 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain YabA PF06156.13 CDO73345.1 - 0.00082 20.0 2.2 0.06 14.0 0.1 2.5 2 0 0 2 2 2 1 Initiation control protein YabA CPT PF07931.12 CDO73345.1 - 0.061 13.2 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_9 PF12781.7 CDO73345.1 - 0.081 12.0 0.5 0.39 9.8 0.1 2.2 2 0 0 2 2 2 0 ATP-binding dynein motor region FlaC_arch PF05377.11 CDO73345.1 - 0.12 12.8 2.4 2.8 8.4 1.4 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DPPIV_rep PF18811.1 CDO73345.1 - 0.27 11.2 0.5 0.47 10.5 0.5 1.3 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region NPV_P10 PF05531.12 CDO73345.1 - 0.99 9.9 3.2 5.2 7.6 1.4 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SYCE1 PF15233.6 CDO73345.1 - 1.3 9.1 6.9 2 8.5 3.6 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 COG2 PF06148.11 CDO73345.1 - 1.5 8.9 5.2 0.41 10.7 1.7 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YscO-like PF16789.5 CDO73345.1 - 1.7 8.6 12.8 1.4 8.9 6.1 2.3 2 0 0 2 2 2 0 YscO-like protein AAA_13 PF13166.6 CDO73345.1 - 3.2 6.3 9.8 12 4.4 9.8 1.7 1 1 0 1 1 1 0 AAA domain ZapB PF06005.12 CDO73345.1 - 5.1 7.6 12.1 1.2 9.6 2.6 3.3 3 0 0 3 3 3 0 Cell division protein ZapB ATG16 PF08614.11 CDO73345.1 - 5.3 7.2 16.3 0.46 10.7 11.1 2.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CDO73345.1 - 6 7.4 13.9 0.58 10.7 6.3 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 CDO73345.1 - 7.3 7.0 9.9 8.1 6.8 4.4 2.2 1 1 1 2 2 2 0 Fez1 Atg14 PF10186.9 CDO73345.1 - 7.8 5.5 9.1 4.9 6.1 2.0 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 CDO73345.1 - 8.8 6.6 8.2 3 8.1 0.5 2.7 3 1 0 3 3 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 CDO73345.1 - 9.5 5.0 13.2 0.11 11.4 4.3 2.1 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF4246 PF14033.6 CDO73346.1 - 1.1e-126 423.6 0.0 1.3e-126 423.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) PseudoU_synth_1 PF01416.20 CDO73347.1 - 5.3e-06 26.8 0.0 0.0025 18.3 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase NIR_SIR_ferr PF03460.17 CDO73347.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain MTHFR PF02219.17 CDO73348.1 - 3.2e-108 361.4 0.0 4.3e-108 361.0 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PH_12 PF16457.5 CDO73349.1 - 2.9e-33 115.2 0.0 5.3e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 CDO73349.1 - 2.5e-28 99.4 0.1 4.2e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 CDO73349.1 - 1.9e-21 76.6 0.0 9.8e-21 74.3 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) Fungal_trans PF04082.18 CDO73351.1 - 1.5e-07 30.7 0.0 2.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Actin PF00022.19 CDO73352.1 - 1.1e-16 60.5 0.0 1.3e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Actin FtsA PF14450.6 CDO73352.1 - 0.012 16.0 0.0 0.058 13.8 0.0 2.0 2 1 0 2 2 2 0 Cell division protein FtsA Actin_micro PF17003.5 CDO73352.1 - 0.034 13.3 0.1 2.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Putative actin-like family zf-C3HC4 PF00097.25 CDO73353.1 - 0.00064 19.5 12.8 0.0012 18.7 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO73353.1 - 0.00087 19.3 8.5 0.00087 19.3 8.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDO73353.1 - 0.0059 16.4 14.3 0.21 11.5 14.8 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO73353.1 - 0.014 15.8 15.1 0.027 14.8 15.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 CDO73353.1 - 0.015 15.5 11.0 0.035 14.3 11.0 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Exonuc_VII_L PF02601.15 CDO73353.1 - 0.073 12.6 5.8 0.09 12.3 5.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS-augmin3 PF14932.6 CDO73353.1 - 0.098 12.2 8.9 0.14 11.7 8.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3552 PF12072.8 CDO73353.1 - 0.11 11.9 21.0 0.27 10.6 21.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) zf-ANAPC11 PF12861.7 CDO73353.1 - 0.24 11.5 4.8 0.65 10.1 4.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 CDO73353.1 - 0.26 11.2 7.8 0.54 10.2 7.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CDO73353.1 - 0.4 10.9 5.5 0.81 9.9 5.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 CDO73353.1 - 0.76 10.1 11.9 2 8.8 11.9 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDO73353.1 - 1.6 8.7 12.6 6.4 6.7 12.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OmpH PF03938.14 CDO73353.1 - 2.2 8.6 11.3 3.3 8.0 11.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CDO73353.1 - 2.3 7.5 11.0 3.2 7.0 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 CDO73353.1 - 2.7 5.8 3.2 3.5 5.4 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup54 PF13874.6 CDO73353.1 - 2.7 8.1 14.0 1.7 8.7 9.7 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 zf-RING_5 PF14634.6 CDO73353.1 - 3.1 7.9 13.1 7.9 6.5 12.1 2.1 1 1 0 1 1 1 0 zinc-RING finger domain SHE3 PF17078.5 CDO73353.1 - 5.8 6.6 12.8 7.8 6.1 12.4 1.3 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Aldo_ket_red PF00248.21 CDO73354.1 - 1.2e-32 113.4 0.0 1.5e-26 93.3 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DUF3792 PF12670.7 CDO73354.1 - 0.02 15.0 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) DUF4922 PF16269.5 CDO73354.1 - 0.068 12.9 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) ORC5_C PF14630.6 CDO73355.1 - 8.9e-62 209.2 0.0 1.2e-61 208.7 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus DUF4140 PF13600.6 CDO73356.1 - 0.025 15.0 0.1 4.1 7.9 0.1 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Lzipper-MIP1 PF14389.6 CDO73356.1 - 3.1 8.1 8.6 0.38 11.1 2.3 2.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 HemY_N PF07219.13 CDO73357.1 - 0.055 13.7 0.9 0.92 9.7 0.9 2.5 2 0 0 2 2 2 0 HemY protein N-terminus Bestrophin PF01062.21 CDO73358.1 - 4.7e-24 85.3 0.1 9.6e-24 84.3 0.0 1.4 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel HGTP_anticodon PF03129.20 CDO73359.1 - 7.6e-21 74.1 0.0 1.6e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CDO73359.1 - 6.2e-10 39.3 0.0 1.9e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) EBP PF05241.12 CDO73360.1 - 9.9e-06 25.1 2.0 1.3e-05 24.7 2.0 1.2 1 0 0 1 1 1 1 Emopamil binding protein DUF802 PF05650.11 CDO73360.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF802) DUF1192 PF06698.11 CDO73361.1 - 0.46 10.6 0.0 0.46 10.6 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) TIM PF00121.18 CDO73362.1 - 4.6e-92 307.8 0.0 5.3e-92 307.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 CDO73362.1 - 0.083 12.4 0.1 0.14 11.6 0.1 1.3 1 1 0 1 1 1 0 CutC family EPL1 PF10513.9 CDO73364.1 - 2.9e-23 83.0 1.6 6.8e-23 81.8 0.3 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like PMI_typeI PF01238.21 CDO73365.1 - 8.3e-60 202.9 0.0 1e-59 202.7 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I CDH-cyt PF16010.5 CDO73368.1 - 3.9e-55 186.4 0.1 7.1e-55 185.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_C PF05199.13 CDO73368.1 - 7.3e-19 68.7 0.1 1.8e-18 67.4 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CDO73368.1 - 5.1e-18 65.5 0.0 8.9e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FHA PF00498.26 CDO73368.1 - 3.6e-15 56.1 0.1 1.3e-14 54.3 0.0 2.1 2 0 0 2 2 1 1 FHA domain zf-RING_11 PF17123.5 CDO73368.1 - 4.1e-10 39.2 11.2 7.2e-10 38.4 11.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CDO73368.1 - 5.5e-08 33.0 11.6 1.1e-07 32.1 11.6 1.5 1 0 0 1 1 1 1 Ring finger domain FAD_binding_2 PF00890.24 CDO73368.1 - 8.1e-06 25.2 0.0 5.5e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain zf-C3HC4 PF00097.25 CDO73368.1 - 0.00015 21.5 11.4 0.00028 20.7 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAD_binding_3 PF01494.19 CDO73368.1 - 0.00018 20.8 0.2 0.00031 20.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CDO73368.1 - 0.00021 20.8 0.0 0.00044 19.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDO73368.1 - 0.00028 20.2 0.1 0.00055 19.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase zf-C3HC4_2 PF13923.6 CDO73368.1 - 0.00045 20.0 11.8 0.00082 19.2 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HI0933_like PF03486.14 CDO73368.1 - 0.00054 18.8 0.1 0.00092 18.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 CDO73368.1 - 0.00068 19.8 0.1 0.002 18.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-rbx1 PF12678.7 CDO73368.1 - 0.0008 19.6 7.4 0.0015 18.7 7.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Pyr_redox_3 PF13738.6 CDO73368.1 - 0.0012 18.2 0.2 0.013 14.8 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase zf-ANAPC11 PF12861.7 CDO73368.1 - 0.0024 17.9 2.2 0.0044 17.1 2.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Thi4 PF01946.17 CDO73368.1 - 0.012 14.8 0.3 0.035 13.3 0.1 1.8 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 CDO73368.1 - 0.017 14.7 0.3 0.041 13.5 0.1 1.7 2 0 0 2 2 1 0 FAD dependent oxidoreductase zf-RING_5 PF14634.6 CDO73368.1 - 0.024 14.6 9.8 0.046 13.7 9.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDO73368.1 - 0.25 11.4 10.5 0.52 10.4 10.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CDO73368.1 - 0.98 9.3 7.6 1.9 8.4 7.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CDO73368.1 - 2 8.4 11.4 0.31 11.0 6.3 2.1 2 0 0 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 CDO73368.1 - 5.4 6.7 6.8 13 5.5 6.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CDO73368.1 - 8.2 6.4 9.9 15 5.6 9.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Fer2_3 PF13085.6 CDO73369.1 - 3.8e-34 117.0 0.1 5.7e-34 116.4 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CDO73369.1 - 0.0007 20.1 0.1 0.0007 20.1 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CDO73369.1 - 0.0016 18.3 1.4 0.0034 17.3 1.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.6 CDO73369.1 - 0.0071 16.4 0.8 0.04 14.0 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CDO73369.1 - 0.016 15.7 4.5 0.054 13.9 4.5 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Catalase PF00199.19 CDO73370.1 - 9e-192 637.3 0.0 1.1e-191 637.0 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CDO73370.1 - 2.2e-16 59.8 0.1 5.5e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Ribosomal_L14 PF00238.19 CDO73371.1 - 2.4e-35 121.2 0.0 2.9e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RRM_1 PF00076.22 CDO73372.1 - 3.5e-17 62.0 0.0 5.7e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDO73372.1 - 3.5e-06 26.6 0.0 6.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CDO73372.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 RL domain Nup35_RRM_2 PF14605.6 CDO73372.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FlgN PF05130.12 CDO73374.1 - 0.26 11.8 1.6 0.74 10.3 0.1 2.1 2 1 0 2 2 2 0 FlgN protein Aldo_ket_red PF00248.21 CDO73375.1 - 9.2e-71 238.4 0.1 1e-70 238.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pyridox_ox_2 PF12900.7 CDO73375.1 - 0.13 12.2 0.3 10 6.1 0.0 2.5 1 1 1 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Fungal_trans PF04082.18 CDO73376.1 - 3.8e-12 45.8 0.0 6.5e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran_CTD PF16326.5 CDO73376.1 - 0.25 11.6 2.4 0.48 10.7 0.1 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain An_peroxidase PF03098.15 CDO73377.1 - 1.6e-36 126.0 0.0 3.5e-23 82.0 0.0 3.8 1 1 1 2 2 2 2 Animal haem peroxidase DUF2235 PF09994.9 CDO73378.1 - 4.2e-94 315.1 2.4 4.2e-93 311.8 2.4 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sigma70_ner PF04546.13 CDO73378.1 - 0.074 12.9 0.8 0.12 12.2 0.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2235 PF09994.9 CDO73379.1 - 8.2e-93 310.9 0.0 1e-92 310.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 CDO73380.1 - 2.5e-86 289.6 0.0 4.4e-86 288.8 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 CDO73380.1 - 0.098 12.6 0.0 2.3 8.1 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Polysacc_deac_1 PF01522.21 CDO73381.1 - 9e-05 22.4 0.3 0.00041 20.2 0.3 2.1 1 1 0 1 1 1 1 Polysaccharide deacetylase TMEM135_C_rich PF15982.5 CDO73382.1 - 0.00086 19.9 0.2 0.0019 18.8 0.2 1.5 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 COPI_assoc PF08507.10 CDO73382.1 - 0.15 12.1 8.1 1.7 8.7 2.2 2.3 2 0 0 2 2 2 0 COPI associated protein DUF4079 PF13301.6 CDO73382.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Bee_toxin PF17454.2 CDO73382.1 - 2.5 8.2 4.0 0.72 9.9 0.7 1.8 2 0 0 2 2 2 0 Honey bee toxin RseC_MucC PF04246.12 CDO73382.1 - 3 7.8 8.6 0.069 13.1 0.8 2.1 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC ARL6IP6 PF15062.6 CDO73383.1 - 0.73 10.0 4.2 15 5.8 1.1 2.4 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix O-FucT PF10250.9 CDO73384.1 - 4.2e-10 39.8 0.0 5.5e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_hydro_28 PF00295.17 CDO73384.1 - 0.045 12.8 0.2 0.066 12.3 0.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 Porphobil_deam PF01379.20 CDO73384.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain tRNA-synt_His PF13393.6 CDO73385.1 - 4.1e-38 131.4 1.1 5.8e-34 117.8 0.0 2.9 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CDO73385.1 - 9.1e-11 41.8 0.2 1.9e-10 40.8 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CDO73385.1 - 0.00017 21.2 0.1 0.0012 18.4 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs WHEP-TRS PF00458.20 CDO73385.1 - 0.11 12.6 2.4 0.35 11.1 2.4 1.9 1 0 0 1 1 1 0 WHEP-TRS domain tRNA-synt_2d PF01409.20 CDO73385.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Ank_2 PF12796.7 CDO73386.1 - 3.8e-06 27.4 0.0 0.0001 22.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDO73386.1 - 4.5e-06 26.6 0.1 0.5 11.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CDO73386.1 - 3.4e-05 24.0 0.1 0.072 13.4 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDO73386.1 - 5.3e-05 23.7 0.0 0.33 11.6 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CDO73386.1 - 7.2e-05 23.1 0.0 0.011 16.2 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeat Amidohydro_1 PF01979.20 CDO73387.1 - 2.7e-22 79.6 0.1 1.1e-19 70.9 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CDO73387.1 - 1.7e-08 34.4 1.6 1.7e-05 24.5 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family DUF1115 PF06544.12 CDO73388.1 - 1.7e-09 38.0 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RRM_1 PF00076.22 CDO73389.1 - 3.8e-17 61.9 0.0 5.1e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDO73389.1 - 0.066 12.8 0.0 0.094 12.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX5A PF02284.16 CDO73390.1 - 7.8e-44 147.9 0.3 9.6e-44 147.6 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va PUF PF00806.19 CDO73391.1 - 7.8e-11 41.1 0.1 0.0037 16.9 0.0 3.6 3 0 0 3 3 3 3 Pumilio-family RNA binding repeat Pkinase PF00069.25 CDO73392.1 - 3.4e-76 256.1 0.0 4.5e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73392.1 - 1.4e-40 139.2 0.0 2e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 CDO73392.1 - 1.4e-17 64.3 1.0 1.9e-10 41.2 0.0 3.4 2 1 1 3 3 3 3 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 CDO73392.1 - 8.2e-13 48.3 0.3 2.1e-12 46.9 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 CDO73392.1 - 8.1e-07 28.6 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDO73392.1 - 0.00041 20.0 0.1 0.0008 19.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CDO73392.1 - 0.0014 17.7 0.1 0.0021 17.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDO73392.1 - 0.047 13.6 2.5 0.33 10.9 0.6 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family YukC PF10140.9 CDO73392.1 - 0.12 11.1 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC YL1 PF05764.13 CDO73392.1 - 0.49 10.5 2.9 0.77 9.8 2.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein MFS_1 PF07690.16 CDO73393.1 - 1.4e-24 86.7 42.8 5e-15 55.3 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily COX7B PF05392.11 CDO73393.1 - 1.3 8.8 3.8 8.1 6.2 0.0 2.9 3 0 0 3 3 3 0 Cytochrome C oxidase chain VIIB Cnn_1N PF07989.11 CDO73395.1 - 0.012 15.8 3.5 0.012 15.8 3.5 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 FapA PF03961.13 CDO73395.1 - 2.5 6.6 5.8 0.37 9.3 2.2 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF726 PF05277.12 CDO73397.1 - 1.7e-122 408.6 1.4 2.3e-122 408.2 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF3541 PF12060.8 CDO73397.1 - 0.034 13.8 0.5 0.062 13.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) DUF2951 PF11166.8 CDO73397.1 - 0.21 11.8 2.0 4.8 7.5 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) SRP14 PF02290.15 CDO73398.1 - 1.4e-24 86.3 0.0 1.4e-24 86.3 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle 14kD protein Polyhedrin PF00738.18 CDO73398.1 - 0.2 10.9 1.1 0.29 10.4 1.1 1.3 1 0 0 1 1 1 0 Polyhedrin TP_methylase PF00590.20 CDO73399.1 - 6.4e-42 143.9 0.9 6.4e-42 143.9 0.9 1.8 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 CDO73399.1 - 2.2e-12 47.3 0.1 2.8e-11 43.8 0.1 2.3 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CDO73399.1 - 7.9e-10 38.2 0.2 8.7e-07 28.5 0.0 2.5 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 CDO73399.1 - 5.8e-07 28.9 1.8 5.8e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central GntR PF00392.21 CDO73400.1 - 0.12 12.0 0.0 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Abhydrolase_3 PF07859.13 CDO73401.1 - 3.6e-19 69.5 0.0 7.8e-18 65.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDO73401.1 - 1.1e-17 64.0 0.0 2.7e-17 62.7 0.0 1.5 2 0 0 2 2 2 1 Steryl acetyl hydrolase SMC_N PF02463.19 CDO73402.1 - 3e-61 206.6 1.4 1.6e-60 204.3 1.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDO73402.1 - 2e-24 86.1 0.0 9.4e-24 84.0 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CDO73402.1 - 6.2e-10 39.3 0.0 6.2e-10 39.3 0.0 3.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 CDO73402.1 - 6.6e-10 39.3 0.0 5.2e-06 26.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDO73402.1 - 1.1e-06 29.3 31.4 1.1e-06 29.3 31.4 7.9 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.6 CDO73402.1 - 8.1e-06 25.5 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4349 PF14257.6 CDO73402.1 - 0.0065 15.9 2.0 0.0065 15.9 2.0 6.6 4 3 3 7 7 7 1 Domain of unknown function (DUF4349) zf-PARP PF00645.18 CDO73402.1 - 0.16 12.9 4.9 0.63 10.9 1.2 3.8 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ABC_tran PF00005.27 CDO73402.1 - 0.34 11.4 0.0 0.34 11.4 0.0 5.7 5 2 0 5 5 5 0 ABC transporter Pkinase PF00069.25 CDO73403.1 - 5.5e-37 127.6 0.0 8.8e-32 110.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73403.1 - 3.5e-19 69.1 0.0 5e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO73403.1 - 0.016 15.1 0.0 0.055 13.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CDO73403.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDO73403.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF5359 PF17313.2 CDO73404.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5359) Pkinase PF00069.25 CDO73405.1 - 1.2e-40 139.5 0.0 1.8e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73405.1 - 6.8e-29 100.9 0.0 9.4e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO73405.1 - 0.018 15.0 2.6 0.089 12.7 0.0 2.9 3 1 0 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO73405.1 - 0.023 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FUSC PF04632.12 CDO73405.1 - 5.9 5.3 6.3 0.46 8.9 0.1 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family NAD_binding_2 PF03446.15 CDO73406.1 - 2e-23 83.3 0.0 3e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CDO73406.1 - 1.4e-07 31.7 0.0 2.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 CDO73406.1 - 1.3e-06 28.5 0.0 2.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CDO73406.1 - 0.00015 22.3 0.0 0.00028 21.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 CDO73406.1 - 0.2 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Mfp-3 PF04202.13 CDO73407.1 - 0.17 12.3 0.3 0.31 11.5 0.3 1.4 1 0 0 1 1 1 0 Foot protein 3 Fip1 PF05182.13 CDO73408.1 - 2.9e-20 71.5 1.9 4.6e-20 70.9 1.9 1.3 1 0 0 1 1 1 1 Fip1 motif DUF5421 PF17458.2 CDO73408.1 - 1 8.7 4.1 2 7.7 4.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Ribosomal_60s PF00428.19 CDO73408.1 - 8.2 7.1 11.6 1.3 9.7 6.0 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cnd1 PF12717.7 CDO73409.1 - 0.006 16.6 0.0 0.0091 16.1 0.0 1.4 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CDO73409.1 - 0.024 14.7 0.0 0.024 14.7 0.0 2.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CDO73409.1 - 0.031 14.5 0.1 3.8 8.0 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.6 CDO73409.1 - 0.053 14.0 0.1 3.1 8.4 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat Atx10homo_assoc PF09759.9 CDO73409.1 - 0.13 12.3 0.1 0.61 10.1 0.0 2.1 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain KAP PF05804.12 CDO73409.1 - 0.19 9.9 0.0 0.28 9.3 0.0 1.3 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) DNA_pol_phi PF04931.13 CDO73410.1 - 4 5.4 4.3 14 3.7 4.8 1.5 2 0 0 2 2 2 0 DNA polymerase phi TPX2 PF06886.11 CDO73411.1 - 7.3e-09 35.7 25.9 7.3e-09 35.7 25.9 2.1 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) UPF0564 PF10595.9 CDO73411.1 - 1.5e-05 24.3 4.1 1.5e-05 24.3 4.1 2.7 2 1 1 3 3 3 1 Uncharacterised protein family UPF0564 Fasciclin PF02469.22 CDO73412.1 - 1.5e-09 38.1 0.0 2.8e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain Aldo_ket_red PF00248.21 CDO73413.1 - 1.1e-67 228.4 0.0 1.3e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Adap_comp_sub PF00928.21 CDO73414.1 - 5.4e-18 65.3 0.0 8.4e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDO73414.1 - 1.2e-05 25.3 0.1 2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ubiquitin PF00240.23 CDO73416.1 - 1.6e-34 117.5 0.5 2.1e-34 117.1 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CDO73416.1 - 1.2e-26 92.4 10.1 2.2e-26 91.5 10.1 1.5 1 1 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CDO73416.1 - 3.1e-16 58.9 0.6 4.9e-16 58.3 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDO73416.1 - 2.3e-05 24.8 0.1 8.4e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CDO73416.1 - 0.0051 16.7 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDO73416.1 - 0.0057 17.0 0.0 0.0091 16.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDO73416.1 - 0.0083 16.2 0.1 0.016 15.3 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CDO73416.1 - 0.015 15.3 1.1 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CDO73416.1 - 0.032 14.8 0.0 0.066 13.8 0.0 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Utp14 PF04615.13 CDO73417.1 - 4.7e-189 630.6 71.9 3.8e-131 439.1 61.2 3.0 2 1 1 3 3 3 2 Utp14 protein Nramp PF01566.18 CDO73418.1 - 1.2e-90 304.0 17.5 1.9e-51 175.2 6.7 2.4 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein Pannexin_like PF12534.8 CDO73418.1 - 0.14 11.2 0.0 2.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 PHD PF00628.29 CDO73420.1 - 0.013 15.4 8.4 0.033 14.1 5.9 2.4 2 0 0 2 2 2 0 PHD-finger DUF2310 PF10071.9 CDO73420.1 - 0.085 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) ING PF12998.7 CDO73421.1 - 3.9e-08 33.8 0.0 4.8e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DnaJ PF00226.31 CDO73422.1 - 1.1e-14 54.2 0.2 1.8e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 CDO73422.1 - 1.2e-13 50.6 0.2 1.9e-13 49.9 0.2 1.3 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_4 PF13717.6 CDO73422.1 - 0.17 11.8 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain OB_NTP_bind PF07717.16 CDO73424.1 - 0.03 14.7 0.0 0.041 14.2 0.0 1.2 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CDO73425.1 - 1.3e-17 64.0 0.3 1.3e-17 64.0 0.3 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDO73425.1 - 2.8e-10 40.5 0.1 6.8e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDO73425.1 - 8.9e-06 25.6 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDO73425.1 - 0.03 14.6 0.0 0.077 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CDO73425.1 - 0.079 12.0 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 CDO73425.1 - 0.085 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain GETHR PF05671.11 CDO73425.1 - 3 7.3 4.7 24 4.4 1.1 2.5 2 0 0 2 2 2 0 GETHR pentapeptide repeat (5 copies) HA2 PF04408.23 CDO73426.1 - 4.2e-25 88.1 1.0 7.9e-25 87.2 0.1 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDO73426.1 - 2.8e-23 82.1 0.0 5.6e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDO73426.1 - 2.4e-13 50.4 0.0 7.3e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CDO73426.1 - 1.3e-06 28.6 0.2 3e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 CDO73426.1 - 2.8e-05 24.0 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDO73426.1 - 8.9e-05 22.8 0.0 0.00025 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDO73426.1 - 0.00034 19.8 0.0 0.00089 18.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 CDO73426.1 - 0.00099 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDO73426.1 - 0.016 15.6 0.1 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CDO73426.1 - 0.017 14.4 0.0 0.039 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CDO73426.1 - 0.036 14.6 1.3 0.75 10.3 0.1 3.1 2 1 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 CDO73426.1 - 0.16 12.0 0.1 1.2 9.2 0.1 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDO73426.1 - 0.17 11.5 0.4 0.37 10.4 0.4 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DIOX_N PF14226.6 CDO73427.1 - 3.5e-12 47.1 0.0 5.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Adaptin_N PF01602.20 CDO73429.1 - 5.3e-108 361.8 0.0 7.1e-108 361.4 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDO73429.1 - 3.4e-11 43.5 1.6 6.1e-07 29.6 0.0 3.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CDO73429.1 - 1.9e-07 30.7 2.1 0.64 10.4 0.0 6.7 7 0 0 7 7 6 2 HEAT repeat HEAT_2 PF13646.6 CDO73429.1 - 3.6e-06 27.3 13.5 0.0016 18.8 0.1 6.4 7 1 1 8 8 8 2 HEAT repeats RTP1_C1 PF10363.9 CDO73429.1 - 0.00021 21.4 2.6 0.11 12.7 0.0 3.4 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CDO73429.1 - 0.0056 17.2 9.6 0.1 13.1 0.1 6.0 7 1 1 8 8 7 1 HEAT-like repeat ParcG PF10274.9 CDO73429.1 - 0.0059 16.7 0.9 4.5 7.4 0.0 3.3 3 1 0 3 3 3 1 Parkin co-regulated protein AP3D1 PF06375.11 CDO73429.1 - 0.014 15.6 10.2 1.5 9.1 0.2 4.0 3 1 0 4 4 4 0 AP-3 complex subunit delta-1 Cnd3 PF12719.7 CDO73429.1 - 0.02 14.1 0.2 0.5 9.5 0.3 2.8 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Nipped-B_C PF12830.7 CDO73429.1 - 0.061 13.3 2.0 3.7 7.5 0.0 3.1 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Arm PF00514.23 CDO73429.1 - 0.066 13.3 0.0 8.5 6.6 0.0 3.6 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat TAF1_subA PF14929.6 CDO73429.1 - 0.073 12.5 0.1 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 TAF RNA Polymerase I subunit A Proteasom_PSMB PF10508.9 CDO73429.1 - 0.094 11.2 0.8 2.6 6.5 0.2 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit FANCI_S1 PF14675.6 CDO73429.1 - 0.14 11.7 0.7 1.3 8.6 0.0 2.6 2 1 1 3 3 3 0 FANCI solenoid 1 Pkinase PF00069.25 CDO73430.1 - 5.5e-72 242.3 0.0 7.3e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73430.1 - 1.6e-51 175.1 0.0 2.3e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO73430.1 - 2e-05 23.6 0.0 3.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDO73430.1 - 0.00015 21.2 0.0 0.0066 15.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDO73430.1 - 0.0014 17.7 0.0 0.22 10.4 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain DUF1241 PF06840.11 CDO73430.1 - 0.0025 17.5 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) DUF3806 PF12713.7 CDO73432.1 - 0.026 14.3 0.1 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) ADH_zinc_N PF00107.26 CDO73434.1 - 5.9e-27 94.2 0.1 9.6e-27 93.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO73434.1 - 7.7e-18 65.8 0.0 2.3e-17 64.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 CDO73434.1 - 0.0087 16.3 0.1 0.1 12.8 0.1 2.3 2 0 0 2 2 2 1 TrkA-N domain PA PF02225.22 CDO73434.1 - 0.019 15.0 0.0 0.058 13.4 0.0 1.7 1 1 0 1 1 1 0 PA domain SIS_2 PF13580.6 CDO73434.1 - 0.068 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 SIS domain ADH_N PF08240.12 CDO73434.1 - 0.079 12.8 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 CDO73434.1 - 0.16 11.4 2.4 0.29 10.6 1.2 1.9 1 1 0 2 2 2 0 short chain dehydrogenase Y_phosphatase PF00102.27 CDO73435.1 - 1.1e-39 136.4 0.0 6.5e-38 130.6 0.0 2.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDO73435.1 - 0.00052 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CDO73435.1 - 0.029 14.3 0.1 0.063 13.2 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.20 CDO73435.1 - 0.14 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain p450 PF00067.22 CDO73436.1 - 3.8e-52 177.6 0.0 1.2e-51 175.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CDO73437.1 - 1.3e-54 185.7 0.0 1.5e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vps62 PF06101.11 CDO73438.1 - 8.8e-11 40.8 0.1 1.5e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 RabGAP-TBC PF00566.18 CDO73439.1 - 9.1e-47 159.5 0.0 1.2e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mg_trans_NIPA PF05653.14 CDO73441.1 - 5.5e-80 268.6 24.8 8e-80 268.1 24.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CDO73441.1 - 8.9e-06 25.9 6.2 8.9e-06 25.9 6.2 3.1 3 0 0 3 3 3 1 EamA-like transporter family Tmemb_161AB PF10268.9 CDO73441.1 - 0.00096 17.9 7.6 0.0018 17.0 7.6 1.3 1 0 0 1 1 1 1 Predicted transmembrane protein 161AB Trp_oprn_chp PF09534.10 CDO73441.1 - 0.019 14.8 1.6 0.037 13.8 0.3 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3796 PF12676.7 CDO73441.1 - 0.39 11.1 7.7 0.97 9.9 7.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Ac76 PF05814.11 CDO73441.1 - 2.1 8.4 7.1 2.4 8.2 0.5 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) DUF2208 PF09973.9 CDO73441.1 - 8.7 5.9 10.8 2.2 7.8 7.3 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Lactonase PF10282.9 CDO73442.1 - 4.4e-12 45.9 0.0 2.3e-08 33.7 0.0 3.0 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.11 CDO73442.1 - 0.0021 17.2 0.0 0.079 12.0 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1513) F-box-like PF12937.7 CDO73443.1 - 5.3e-05 23.0 2.0 0.00014 21.7 2.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO73443.1 - 0.00093 19.0 1.0 0.0021 17.9 1.0 1.7 1 0 0 1 1 1 1 F-box domain RPEL PF02755.15 CDO73443.1 - 0.033 13.9 0.0 0.086 12.6 0.0 1.8 1 0 0 1 1 1 0 RPEL repeat HTH_17 PF12728.7 CDO73443.1 - 0.32 11.2 3.0 0.25 11.6 0.5 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain CutC PF03932.14 CDO73444.1 - 4.2e-39 134.1 0.0 5.2e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 CutC family PEP_mutase PF13714.6 CDO73444.1 - 0.024 14.1 0.1 0.036 13.5 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Cyt-b5 PF00173.28 CDO73445.1 - 3.8e-06 27.0 0.0 9.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 CDO73445.1 - 0.0024 17.7 0.3 0.0043 16.9 0.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase BTB PF00651.31 CDO73446.1 - 0.045 14.0 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain p450 PF00067.22 CDO73447.1 - 1.2e-51 176.0 0.0 3.3e-46 158.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Bromodomain PF00439.25 CDO73448.1 - 6.6e-36 122.3 6.2 2.1e-19 69.3 0.3 2.6 3 0 0 3 3 3 2 Bromodomain PIP5K PF01504.18 CDO73448.1 - 0.042 13.1 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DHHC PF01529.20 CDO73449.1 - 1.5e-37 128.7 10.5 1.9e-37 128.4 10.5 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Gar1 PF04410.14 CDO73451.1 - 4.3e-37 127.3 0.1 1.9e-36 125.2 0.1 2.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region SAS4 PF15460.6 CDO73451.1 - 0.0015 18.6 5.2 0.0015 18.6 5.2 1.9 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.6 CDO73451.1 - 0.0039 17.8 6.3 0.0039 17.8 6.3 4.0 4 1 0 4 4 4 1 PEHE domain Hydrophobin PF01185.18 CDO73454.1 - 4e-23 81.9 11.5 4.7e-23 81.6 11.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Kelch_5 PF13854.6 CDO73456.1 - 1.9e-20 72.4 1.3 0.00012 21.9 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 CDO73456.1 - 5.8e-20 71.1 7.9 2.5e-06 27.6 0.1 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CDO73456.1 - 1e-18 66.9 5.4 3.4e-07 30.3 0.3 5.6 3 2 2 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CDO73456.1 - 9.2e-17 60.8 10.8 1e-05 25.5 0.0 5.5 4 2 1 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CDO73456.1 - 1.4e-15 56.6 1.0 8.8e-05 22.0 0.3 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 CDO73456.1 - 3.6e-14 52.1 8.3 0.0075 16.2 0.7 5.5 5 1 0 5 5 5 4 Kelch motif Fez1 PF06818.15 CDO73456.1 - 0.0004 20.9 5.5 0.0004 20.9 5.5 4.6 3 1 1 4 4 3 1 Fez1 HOOK PF05622.12 CDO73456.1 - 0.00086 17.6 7.2 0.00086 17.6 7.2 3.3 2 1 0 2 2 1 1 HOOK protein Pox_A_type_inc PF04508.12 CDO73456.1 - 0.011 15.5 15.4 0.12 12.3 0.1 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat ZapB PF06005.12 CDO73456.1 - 0.11 13.0 0.3 0.11 13.0 0.3 7.4 5 2 0 5 5 4 0 Cell division protein ZapB Tropomyosin PF00261.20 CDO73456.1 - 0.83 9.0 56.6 14 4.9 6.8 4.4 2 1 0 2 2 2 0 Tropomyosin FlaC_arch PF05377.11 CDO73456.1 - 1.3 9.5 25.0 0.25 11.8 3.4 4.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 CDO73456.1 - 2.4 8.3 24.9 0.67 10.1 2.0 5.2 4 1 0 4 4 4 0 bZIP transcription factor Vac_Fusion PF02346.16 CDO73456.1 - 2.6 7.7 5.6 38 4.0 0.2 3.2 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 S1 PF00575.23 CDO73457.1 - 1.7e-63 210.9 23.9 4.3e-15 55.8 0.4 10.9 10 1 0 10 10 10 10 S1 RNA binding domain TPR_19 PF14559.6 CDO73457.1 - 3.3e-08 33.9 0.0 0.012 16.1 0.0 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat NRDE-2 PF08424.10 CDO73457.1 - 1.3e-05 24.6 10.2 0.0057 15.8 1.1 3.4 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CDO73457.1 - 1.3e-05 25.6 0.0 0.47 11.4 0.0 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 CDO73457.1 - 4.8e-05 23.5 12.2 0.00062 19.8 0.0 3.8 2 1 1 3 3 2 2 Suppressor of forked protein (Suf) TPR_16 PF13432.6 CDO73457.1 - 6.7e-05 23.5 0.0 0.24 12.1 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat S1_2 PF13509.6 CDO73457.1 - 0.0001 22.3 4.5 20 5.4 0.0 7.2 7 1 0 7 7 7 0 S1 domain TPR_15 PF13429.6 CDO73457.1 - 0.00022 20.6 2.0 0.0073 15.6 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 CDO73457.1 - 0.00071 19.5 14.8 0.004 17.1 0.1 6.9 8 0 0 8 8 8 1 RNase II-type exonuclease C-terminal S1 domain ANAPC3 PF12895.7 CDO73457.1 - 0.0017 18.6 0.0 0.0074 16.5 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CDO73457.1 - 0.0019 18.4 0.2 2.6 8.4 0.0 3.4 3 1 1 4 4 3 1 Tetratricopeptide repeat DUF2110 PF09883.9 CDO73457.1 - 0.002 17.7 1.1 0.36 10.4 0.1 4.1 5 0 0 5 5 5 1 Uncharacterized protein conserved in archaea (DUF2110) TPR_6 PF13174.6 CDO73457.1 - 0.0029 18.1 0.0 11 6.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat CSD PF00313.22 CDO73457.1 - 0.036 13.9 0.3 7.4 6.5 0.0 3.3 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain TPR_2 PF07719.17 CDO73457.1 - 0.059 13.5 0.2 14 6.1 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat SF3A2 PF16835.5 CDO73458.1 - 1.1e-36 125.1 0.1 1.6e-36 124.5 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CDO73458.1 - 2e-06 28.0 0.7 2e-06 28.0 0.7 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 CDO73458.1 - 0.0076 15.8 0.9 0.016 14.7 0.9 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.9 CDO73458.1 - 0.019 14.9 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein Ribonuclease PF00545.20 CDO73459.1 - 1.2e-05 25.9 0.1 2.3e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 ribonuclease FAM220 PF15487.6 CDO73460.1 - 1.8 8.1 9.1 1.2 8.7 7.7 1.5 1 1 0 1 1 1 0 FAM220 family Drc1-Sld2 PF11719.8 CDO73461.1 - 4.8e-13 49.5 13.1 4.8e-13 49.5 13.1 3.1 1 1 2 3 3 3 1 DNA replication and checkpoint protein SPOC PF07744.13 CDO73462.1 - 0.037 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 SPOC domain PCI PF01399.27 CDO73463.1 - 3.7e-18 66.0 0.0 1.2e-17 64.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 CDO73463.1 - 2.5e-05 24.3 0.7 7.8e-05 22.7 0.7 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Pro_3_hydrox_C PF05373.11 CDO73463.1 - 0.034 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal LPP PF04728.13 CDO73463.1 - 0.11 12.9 0.6 0.53 10.7 0.1 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper LUC7 PF03194.15 CDO73463.1 - 0.16 11.7 2.4 1.7 8.3 2.2 2.1 1 1 0 1 1 1 0 LUC7 N_terminus MRP-S25 PF13741.6 CDO73464.1 - 4.6e-53 180.1 6.3 1e-51 175.7 4.5 2.3 1 1 1 2 2 2 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 CDO73464.1 - 0.0001 22.6 0.7 0.00024 21.4 0.7 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 Pal1 PF08316.11 CDO73467.1 - 0.081 13.7 0.7 0.28 11.9 0.0 2.3 2 0 0 2 2 2 0 Pal1 cell morphology protein GARS_A PF01071.19 CDO73468.1 - 3.2e-80 268.5 0.0 4.8e-80 267.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 CDO73468.1 - 7.3e-35 119.6 0.0 3.2e-34 117.6 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 CDO73468.1 - 8.5e-35 120.2 0.0 1.7e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 CDO73468.1 - 1.2e-26 92.7 0.2 3.4e-26 91.3 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CDO73468.1 - 1.7e-15 57.4 0.7 2e-14 54.0 0.9 2.6 2 1 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 CDO73468.1 - 0.00058 19.4 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 CDO73468.1 - 0.002 18.2 0.2 0.0045 17.1 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 CDO73468.1 - 0.045 13.4 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Ank_2 PF12796.7 CDO73469.1 - 9.5e-11 42.1 0.0 1.7e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_4 PF18044.1 CDO73469.1 - 2.2e-08 33.7 13.9 0.0004 20.1 3.1 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Ank_5 PF13857.6 CDO73469.1 - 1.8e-07 31.3 0.0 5e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) zf-CCCH_2 PF14608.6 CDO73469.1 - 2.1e-07 31.1 17.3 2.2e-06 27.9 4.6 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Ank_3 PF13606.6 CDO73469.1 - 4e-07 29.8 0.0 0.00067 19.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CDO73469.1 - 3e-06 27.7 0.0 5.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CDO73469.1 - 2.2e-05 24.7 0.0 0.00039 20.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat zf_CCCH_4 PF18345.1 CDO73469.1 - 4.3e-05 23.4 16.5 0.00029 20.8 2.1 2.8 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 CDO73469.1 - 4.3e-05 23.3 11.4 0.017 15.1 2.2 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDO73469.1 - 0.0011 19.7 0.5 0.0011 19.7 0.5 2.3 2 0 0 2 2 2 1 Torus domain zf-CCCH_3 PF15663.5 CDO73469.1 - 0.26 11.5 2.8 7.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger containing family NAD_Gly3P_dh_C PF07479.14 CDO73470.1 - 1.3e-49 168.1 0.5 2e-49 167.5 0.5 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CDO73470.1 - 3.2e-30 105.2 0.0 5.6e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 CDO73470.1 - 5.1e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 CDO73470.1 - 3.8e-05 24.2 0.0 0.00028 21.4 0.0 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CDO73470.1 - 0.0018 18.4 0.0 0.0059 16.8 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CDO73470.1 - 0.12 12.4 0.0 0.47 10.5 0.0 2.1 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PDH PF02153.17 CDO73470.1 - 0.18 10.8 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase SNARE PF05739.19 CDO73471.1 - 9.2e-14 51.2 0.1 2.4e-13 49.9 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 CDO73471.1 - 3.2e-07 29.4 1.9 3.5e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 CDO73471.1 - 0.0001 22.4 0.2 0.0001 22.4 0.2 3.4 4 0 0 4 4 3 1 SNARE-complex protein Syntaxin-18 N-terminus Syntaxin PF00804.25 CDO73471.1 - 0.00017 21.3 15.4 0.00026 20.7 0.8 2.7 2 1 1 3 3 3 1 Syntaxin FlxA PF14282.6 CDO73471.1 - 0.0011 18.9 4.2 0.0011 18.9 4.2 2.9 3 1 0 3 3 3 1 FlxA-like protein DUF1351 PF07083.11 CDO73471.1 - 0.004 17.0 2.4 0.004 17.0 2.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1351) DUF3626 PF12294.8 CDO73471.1 - 0.032 13.3 0.1 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3626) MtrB PF05440.12 CDO73471.1 - 0.051 14.0 0.7 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF16 PF01519.16 CDO73471.1 - 0.053 14.0 0.4 0.053 14.0 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 CDO73471.1 - 0.062 13.9 10.2 0.15 12.7 0.9 3.0 3 0 0 3 3 2 0 SlyX BLOC1_2 PF10046.9 CDO73471.1 - 0.12 12.7 5.9 0.71 10.2 0.5 3.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cluap1 PF10234.9 CDO73471.1 - 0.21 10.9 10.0 0.22 10.9 2.9 2.5 2 1 0 2 2 2 0 Clusterin-associated protein-1 MIF4G_like_2 PF09090.11 CDO73471.1 - 0.37 10.2 6.5 5.7 6.3 2.6 2.2 2 0 0 2 2 2 0 MIF4G like Spectrin PF00435.21 CDO73471.1 - 0.39 11.2 7.4 0.89 10.1 0.3 3.2 2 1 0 2 2 2 0 Spectrin repeat Mer2 PF09074.10 CDO73471.1 - 0.7 9.7 9.1 0.4 10.5 4.9 2.1 2 0 0 2 2 2 0 Mer2 End3 PF12761.7 CDO73471.1 - 0.95 9.6 9.4 0.24 11.6 0.7 2.7 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 AcylCoA_dehyd_C PF12186.8 CDO73471.1 - 1.2 9.3 5.2 1.6 8.9 1.2 2.4 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal Osmo_CC PF08946.10 CDO73471.1 - 1.4 9.2 4.0 2.8 8.3 0.3 2.9 3 0 0 3 3 3 0 Osmosensory transporter coiled coil NPV_P10 PF05531.12 CDO73471.1 - 2 8.9 9.5 1.2 9.7 2.3 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 CDO73471.1 - 6.1 6.9 9.9 3.4 7.7 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MSL1_dimer PF16801.5 CDO73471.1 - 8.7 6.2 10.0 2.5 7.9 0.1 3.1 3 0 0 3 3 3 0 Dimerisation domain of Male-specific-Lethal 1 DDE_3 PF13358.6 CDO73472.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.22 CDO73473.1 - 6.7e-12 45.1 0.0 1.5e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 CDO73474.1 - 1.1e-35 122.4 0.2 1.4e-35 122.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CDO73474.1 - 0.014 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 CDO73474.1 - 0.047 14.0 0.1 0.076 13.3 0.1 1.4 1 1 0 1 1 1 0 RWD domain DIOX_N PF14226.6 CDO73475.1 - 5.7e-05 23.8 0.1 0.00017 22.3 0.1 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO73475.1 - 0.00092 19.7 0.0 0.0016 18.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NAAA-beta PF15508.6 CDO73475.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Chorismate_bind PF00425.18 CDO73476.1 - 2.3e-65 220.7 0.0 3e-59 200.7 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.28 CDO73476.1 - 2.6e-31 108.9 0.0 3.8e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 CDO73476.1 - 1.3e-18 67.6 0.0 5.4e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 CDO73476.1 - 0.00079 19.2 1.1 0.005 16.6 1.1 2.0 1 1 0 1 1 1 1 Peptidase C26 HEAT PF02985.22 CDO73477.1 - 0.0018 18.4 0.4 0.036 14.3 0.1 3.5 3 0 0 3 3 3 1 HEAT repeat TraC_F_IV PF11130.8 CDO73477.1 - 0.061 12.9 1.5 0.15 11.6 0.4 2.0 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer Arrestin_C PF02752.22 CDO73478.1 - 3.1e-13 50.3 0.0 6.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain adh_short_C2 PF13561.6 CDO73479.1 - 9.6e-49 166.0 0.2 3.1e-48 164.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO73479.1 - 8.1e-32 110.3 0.1 5.9e-28 97.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 CDO73479.1 - 1.6e-05 24.9 0.1 5.5e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 CDO73479.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Vta1 PF04652.16 CDO73480.1 - 4.3e-49 166.2 0.7 5.9e-49 165.8 0.7 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 CDO73480.1 - 3.7e-16 58.5 0.1 3.7e-16 58.5 0.1 2.4 3 0 0 3 3 3 1 Vta1 C-terminal domain Pectinesterase PF01095.19 CDO73481.1 - 3e-20 72.1 4.6 9.9e-13 47.5 1.5 2.8 1 1 1 2 2 2 2 Pectinesterase MSP1a PF11670.8 CDO73482.1 - 0.52 9.6 1.9 0.95 8.7 1.9 1.4 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) RNase_T PF00929.24 CDO73483.1 - 0.15 12.6 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Exonuclease TetR_C_6 PF13977.6 CDO73484.1 - 0.036 14.3 12.1 2.4 8.4 0.0 4.7 3 1 1 4 4 4 0 BetI-type transcriptional repressor, C-terminal PPR_2 PF13041.6 CDO73484.1 - 0.23 11.7 0.0 0.73 10.1 0.0 1.9 2 0 0 2 2 2 0 PPR repeat family Cut8 PF08559.10 CDO73485.1 - 2.4e-15 56.8 0.1 4.3e-13 49.4 0.0 2.7 2 1 0 2 2 2 2 Cut8, nuclear proteasome tether protein Cas1_AcylT PF07779.12 CDO73486.1 - 2.7e-149 498.1 10.7 3.4e-149 497.8 10.7 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 CDO73486.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Rhomboid PF01694.22 CDO73487.1 - 8.2e-33 113.5 15.3 8.2e-33 113.5 15.3 1.5 1 1 1 2 2 2 1 Rhomboid family TssN PF17555.2 CDO73487.1 - 3 7.2 7.0 4.2 6.7 5.8 1.9 1 1 1 2 2 2 0 Type VI secretion system, TssN SnoaL PF07366.12 CDO73488.1 - 0.0076 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DIL PF01843.19 CDO73489.1 - 2.1e-28 98.6 0.4 4.6e-28 97.5 0.4 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 CDO73489.1 - 3.9e-07 30.6 0.0 9.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDO73489.1 - 1.3e-06 28.8 0.0 1.7e-05 25.3 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDO73489.1 - 4.7e-06 26.8 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CDO73489.1 - 5.5e-06 26.6 0.2 0.0023 18.3 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CDO73489.1 - 0.00032 20.9 0.0 0.0078 16.6 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Rrp15p PF07890.12 CDO73490.1 - 5.6e-28 97.9 2.9 5.6e-28 97.9 2.9 2.2 1 1 1 2 2 2 1 Rrp15p CDC45 PF02724.14 CDO73490.1 - 3.3 5.9 7.7 4.1 5.6 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein BLOC1S3 PF15753.5 CDO73490.1 - 6.8 6.8 8.6 1 9.5 4.7 1.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 CLTH PF10607.9 CDO73491.1 - 8e-37 126.4 0.2 1.1e-36 126.0 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CDO73491.1 - 1.3e-10 40.8 0.3 3.5e-10 39.5 0.3 1.8 1 0 0 1 1 1 1 LisH Pkinase PF00069.25 CDO73492.1 - 2.9e-66 223.5 0.0 3.9e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73492.1 - 1.2e-45 155.9 0.0 1.9e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO73492.1 - 1.9e-09 37.3 0.0 1.2e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Ras_bdg_2 PF14847.6 CDO73492.1 - 0.00022 21.5 0.0 0.00042 20.6 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kdo PF06293.14 CDO73492.1 - 0.0012 18.3 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDO73492.1 - 0.0013 17.5 0.0 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO73492.1 - 0.049 13.6 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO73492.1 - 0.096 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain MRP-S28 PF10213.9 CDO73494.1 - 7.6e-31 107.2 0.0 1.1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein CN_hydrolase PF00795.22 CDO73495.1 - 3.3e-42 144.7 0.0 4.3e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Septin PF00735.18 CDO73496.1 - 4.6e-120 400.1 0.0 4.6e-120 400.1 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CDO73496.1 - 8.9e-08 32.2 0.1 2.8e-07 30.6 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CDO73496.1 - 0.00023 21.7 4.7 0.049 14.2 0.0 2.7 3 0 0 3 3 3 2 ABC transporter GTP_EFTU PF00009.27 CDO73496.1 - 0.00065 19.3 3.6 0.046 13.3 0.0 3.5 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDO73496.1 - 0.00065 19.6 8.4 0.0011 18.9 0.5 3.3 3 1 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 CDO73496.1 - 0.0013 19.0 0.0 0.0081 16.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain Ras PF00071.22 CDO73496.1 - 0.0038 16.8 0.0 0.027 14.1 0.0 2.3 2 0 0 2 2 2 1 Ras family AIG1 PF04548.16 CDO73496.1 - 0.0071 15.7 0.4 0.016 14.5 0.0 1.8 2 0 0 2 2 2 1 AIG1 family AAA_29 PF13555.6 CDO73496.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CDO73496.1 - 0.023 15.1 0.0 0.07 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 CDO73496.1 - 0.057 13.5 4.7 1.4 9.0 0.1 3.0 2 1 1 3 3 3 0 Dynamin family Roc PF08477.13 CDO73496.1 - 0.087 13.0 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Coiled-coil_56 PF09813.9 CDO73496.1 - 0.27 11.3 2.5 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Exonuc_VII_L PF02601.15 CDO73496.1 - 0.57 9.7 3.5 0.9 9.0 3.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Strep_SA_rep PF06696.11 CDO73496.1 - 4.2 7.5 11.8 0.41 10.7 4.0 2.4 1 1 1 2 2 2 0 Streptococcal surface antigen repeat ATP_bind_1 PF03029.17 CDO73496.1 - 9.4 5.9 9.4 7.1 6.3 0.1 3.5 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Xpo1 PF08389.12 CDO73497.1 - 7e-25 87.8 0.9 1.8e-23 83.2 0.0 3.5 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 CDO73497.1 - 4.6e-06 26.5 0.1 0.00021 21.2 0.0 3.0 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 CDO73497.1 - 0.052 14.1 0.3 4 8.0 0.0 3.9 2 1 2 4 4 4 0 HEAT-like repeat Importin_rep PF18773.1 CDO73497.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Importin 13 repeat PUL PF08324.11 CDO73497.1 - 0.078 12.2 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 PUL domain Cnd1 PF12717.7 CDO73497.1 - 0.083 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 CoA_binding PF02629.19 CDO73498.1 - 3.8e-30 104.4 0.1 7.1e-30 103.6 0.1 1.5 1 0 0 1 1 1 1 CoA binding domain CoA_binding_2 PF13380.6 CDO73498.1 - 8.1e-06 26.3 0.0 1.3e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 CDO73498.1 - 0.031 14.1 1.9 0.066 13.0 0.1 2.2 3 0 0 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain Ligase_CoA PF00549.19 CDO73498.1 - 0.048 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 CoA-ligase GFO_IDH_MocA PF01408.22 CDO73498.1 - 0.068 14.0 0.0 0.14 13.0 0.0 1.5 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ank_5 PF13857.6 CDO73499.1 - 1.5e-15 57.0 0.3 5.1e-15 55.3 0.2 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) ACBP PF00887.19 CDO73499.1 - 1.6e-13 50.6 0.0 3.3e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ligase_CoA PF00549.19 CDO73499.1 - 2.2e-11 43.8 0.0 3.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Ank_2 PF12796.7 CDO73499.1 - 1.2e-10 41.8 0.1 2.7e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDO73499.1 - 3.5e-09 36.7 0.3 2.4e-08 34.1 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CDO73499.1 - 3.2e-08 33.2 0.5 4.5e-06 26.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CDO73499.1 - 4.3e-08 33.5 0.5 1.3e-06 28.8 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ribosomal_S16 PF00886.19 CDO73500.1 - 1.2e-22 79.7 0.1 2e-22 79.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 LSM PF01423.22 CDO73501.1 - 2e-22 78.6 0.2 2.3e-22 78.5 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDO73501.1 - 0.024 14.7 0.0 0.028 14.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 CDO73501.1 - 0.06 13.5 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Arm PF00514.23 CDO73502.1 - 4.3e-92 299.7 21.2 1.7e-12 46.9 0.1 10.5 10 0 0 10 10 10 9 Armadillo/beta-catenin-like repeat 2-Hacid_dh_C PF02826.19 CDO73502.1 - 1.2e-52 177.9 0.0 2e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RPN2_C PF18004.1 CDO73502.1 - 5.2e-41 140.2 2.3 2.9e-39 134.6 2.8 2.4 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 CDO73502.1 - 5.6e-34 116.4 7.2 8.2e-15 55.0 0.1 8.1 5 1 4 10 10 9 5 HEAT repeats PC_rep PF01851.22 CDO73502.1 - 2e-25 87.9 14.1 1.3e-07 31.6 0.0 8.7 9 0 0 9 9 7 5 Proteasome/cyclosome repeat HEAT_EZ PF13513.6 CDO73502.1 - 9.7e-25 86.6 12.7 8.3e-09 35.8 0.1 9.2 6 3 4 10 10 10 5 HEAT-like repeat IBB PF01749.20 CDO73502.1 - 2.6e-24 85.5 0.9 9.8e-24 83.6 0.9 2.1 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.22 CDO73502.1 - 6.2e-21 72.7 3.5 0.00016 21.6 0.0 10.3 11 0 0 11 11 9 3 HEAT repeat Arm_3 PF16186.5 CDO73502.1 - 6.5e-21 73.6 0.3 1.6e-20 72.4 0.3 1.7 1 0 0 1 1 1 1 Atypical Arm repeat 2-Hacid_dh PF00389.30 CDO73502.1 - 1.1e-08 34.8 0.0 2.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Adaptin_N PF01602.20 CDO73502.1 - 1.3e-08 33.8 0.0 0.0012 17.6 0.0 3.6 2 1 1 3 3 3 2 Adaptin N terminal region RICTOR_V PF14668.6 CDO73502.1 - 1.7e-06 28.1 0.7 0.18 12.1 0.0 5.0 3 3 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 CDO73502.1 - 1.3e-05 24.8 0.0 1.3 8.5 0.0 5.0 3 2 3 6 6 6 2 Armadillo-like HEAT_PBS PF03130.16 CDO73502.1 - 0.0024 18.4 7.9 2.5 9.0 0.1 7.0 8 0 0 8 8 6 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 CDO73502.1 - 0.0024 17.3 0.0 0.0071 15.8 0.0 1.7 1 0 0 1 1 1 1 Mo25-like V-ATPase_H_C PF11698.8 CDO73502.1 - 0.012 15.7 0.0 16 5.6 0.0 4.3 5 1 1 6 6 6 0 V-ATPase subunit H NAD_binding_2 PF03446.15 CDO73502.1 - 0.034 14.3 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gcn1_N PF12074.8 CDO73502.1 - 2.4 7.3 7.6 2.2 7.5 0.0 3.4 4 0 0 4 4 4 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal COX6A PF02046.15 CDO73503.1 - 4.7e-27 94.7 0.0 5.4e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa BRCT_2 PF16589.5 CDO73503.1 - 0.079 13.4 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Retrotrans_gag PF03732.17 CDO73505.1 - 0.034 14.4 0.1 0.063 13.5 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Ribul_P_3_epim PF00834.19 CDO73506.1 - 1.4e-53 181.3 0.0 9.8e-26 90.4 0.0 2.0 2 0 0 2 2 2 2 Ribulose-phosphate 3 epimerase family Gly_transf_sug PF04488.15 CDO73507.1 - 1.3e-07 32.1 0.0 2.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CDO73507.1 - 0.00071 19.0 0.4 0.0011 18.4 0.4 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 CDO73507.1 - 0.056 12.7 0.4 0.088 12.1 0.4 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DEAD PF00270.29 CDO73508.1 - 1.3e-20 73.9 0.0 8.3e-20 71.3 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO73508.1 - 2.4e-06 27.8 0.0 5.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO73508.1 - 0.0048 16.9 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4203 PF13886.6 CDO73509.1 - 1e-51 175.5 30.5 1.5e-51 174.9 30.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) U1snRNP70_N PF12220.8 CDO73509.1 - 0.28 11.9 2.8 0.29 11.8 1.0 1.9 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4472 PF14739.6 CDO73510.1 - 0.044 14.5 2.6 0.08 13.7 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) LAG1-DNAbind PF09271.11 CDO73511.1 - 9.9e-28 97.7 0.7 3.7e-16 60.1 0.1 3.1 2 1 1 3 3 3 2 LAG1, DNA binding BTD PF09270.10 CDO73511.1 - 8.1e-18 65.1 0.0 5.1e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain Sugar_tr PF00083.24 CDO73512.1 - 1.5e-84 284.5 14.4 3.5e-67 227.2 10.9 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDO73512.1 - 2.3e-21 76.1 28.8 5.8e-19 68.2 8.7 2.8 2 1 0 3 3 3 2 Major Facilitator Superfamily PPR_2 PF13041.6 CDO73514.1 - 1e-42 144.1 2.6 3.8e-08 33.4 0.0 10.5 6 4 5 11 11 11 9 PPR repeat family PPR_3 PF13812.6 CDO73514.1 - 4.9e-29 100.2 0.0 4.4e-06 26.7 0.0 6.2 5 1 1 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 CDO73514.1 - 1.5e-19 68.8 13.7 0.0064 16.7 0.0 10.4 11 1 0 11 11 11 6 PPR repeat PPR_1 PF12854.7 CDO73514.1 - 9.6e-14 50.8 0.0 0.00048 19.8 0.0 8.4 9 0 0 9 9 9 2 PPR repeat PPR_long PF17177.4 CDO73514.1 - 9.8e-13 48.0 2.5 0.0027 17.1 0.0 4.2 2 1 3 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 CDO73514.1 - 0.037 14.9 20.0 0.16 12.9 0.3 7.2 6 2 2 8 8 8 0 Tetratricopeptide repeat NOD PF06816.13 CDO73514.1 - 0.084 12.5 0.0 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 NOTCH protein TPR_16 PF13432.6 CDO73514.1 - 0.57 10.9 10.1 6.9 7.4 0.6 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDO73514.1 - 0.91 10.3 3.8 2.5 8.9 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 CDO73515.1 - 2.2e-45 154.8 0.0 3.7e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 CDO73515.1 - 1.4e-05 24.6 0.8 0.0047 16.3 0.0 3.0 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 CDO73515.1 - 0.00064 19.8 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 CDO73515.1 - 0.058 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 CDO73515.1 - 0.1 12.4 0.0 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Snf7 PF03357.21 CDO73516.1 - 9.6e-13 48.1 3.4 9.6e-13 48.1 3.4 2.0 2 0 0 2 2 2 1 Snf7 Fungal_trans PF04082.18 CDO73516.1 - 5.6e-08 32.1 0.0 1.3e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain G_glu_transpept PF01019.21 CDO73517.1 - 8e-141 470.3 0.0 9.1e-141 470.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PP2C PF00481.21 CDO73518.1 - 8.8e-26 91.1 0.0 5.5e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CDO73518.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C His_Phos_2 PF00328.22 CDO73519.1 - 5.1e-49 167.6 0.0 6e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_M41 PF01434.18 CDO73520.1 - 5.1e-64 215.7 0.0 7.3e-64 215.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CDO73520.1 - 7e-42 143.0 0.0 1.4e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 CDO73520.1 - 8.8e-13 48.6 0.0 2.1e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_lid_3 PF17862.1 CDO73520.1 - 1e-12 47.7 0.2 2.9e-12 46.2 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CDO73520.1 - 0.00068 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDO73520.1 - 0.0045 17.4 0.1 0.032 14.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 CDO73520.1 - 0.0059 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CDO73520.1 - 0.0086 16.1 0.0 0.04 13.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CDO73520.1 - 0.0096 16.2 0.1 0.51 10.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CDO73520.1 - 0.021 14.9 0.1 0.092 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CDO73520.1 - 0.035 13.8 0.0 0.091 12.5 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.6 CDO73520.1 - 0.063 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 CDO73521.1 - 3.5e-10 39.3 17.7 5.6e-10 38.7 17.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 CDO73522.1 - 2.3e-28 99.1 32.1 2.3e-28 99.1 32.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0113_N PF17833.1 CDO73523.1 - 1.5e-31 108.7 0.1 2.3e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CDO73523.1 - 1.1e-26 92.9 0.0 2e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 CDO73523.1 - 0.05 13.7 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain DEAD PF00270.29 CDO73525.1 - 1.5e-10 41.1 0.0 4.8e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO73525.1 - 2.6e-06 27.8 0.0 1.9e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO73525.1 - 0.0031 17.6 0.0 0.019 15.0 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CENP-Q PF13094.6 CDO73525.1 - 0.11 12.7 1.0 0.24 11.6 1.0 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit OEP PF02321.18 CDO73525.1 - 0.24 11.2 2.4 0.17 11.7 0.2 1.8 2 0 0 2 2 2 0 Outer membrane efflux protein Sec39 PF08314.11 CDO73526.1 - 1.8e-84 284.6 0.0 2.2e-84 284.4 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 KfrA_N PF11740.8 CDO73527.1 - 0.34 11.6 4.1 0.38 11.4 2.4 2.0 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term RVT_1 PF00078.27 CDO73528.1 - 8e-24 84.4 0.0 2.3e-23 82.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO73528.1 - 1.7e-08 34.7 0.0 6.4e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 CDO73528.1 - 0.0042 17.8 0.0 0.01 16.6 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Cgr1 PF03879.14 CDO73529.1 - 1.7e-30 105.5 18.1 2.1e-30 105.3 18.1 1.1 1 0 0 1 1 1 1 Cgr1 family DUF3682 PF12446.8 CDO73529.1 - 0.029 14.8 0.4 0.051 14.1 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) Atrophin-1 PF03154.15 CDO73529.1 - 0.13 10.6 6.2 0.12 10.6 6.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family MCU PF04678.13 CDO73529.1 - 0.15 12.2 4.0 0.17 12.0 4.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter PBP_sp32 PF07222.12 CDO73529.1 - 0.59 9.5 8.9 0.8 9.1 8.8 1.3 1 1 0 1 1 1 0 Proacrosin binding protein sp32 RF-1 PF00472.20 CDO73529.1 - 0.69 9.9 12.2 1.2 9.1 12.1 1.4 1 1 0 1 1 1 0 RF-1 domain Pep3_Vps18 PF05131.14 CDO73530.1 - 3.5e-51 173.0 0.0 6e-51 172.2 0.0 1.4 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CDO73530.1 - 2.8e-14 53.2 0.6 6.3e-05 22.9 0.0 4.1 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 CDO73530.1 - 6.3e-05 23.4 0.1 0.00017 22.0 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 CDO73530.1 - 0.00043 20.2 2.1 0.001 19.0 2.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CDO73530.1 - 0.0023 17.5 1.3 0.0052 16.4 1.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CDO73530.1 - 0.0064 16.2 1.7 0.0064 16.2 1.7 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CDO73530.1 - 0.054 13.5 3.6 0.067 13.2 1.8 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 CDO73530.1 - 0.059 13.7 1.9 0.15 12.4 1.9 1.7 1 0 0 1 1 1 0 Ring finger domain TPR_7 PF13176.6 CDO73530.1 - 0.15 12.1 2.6 46 4.4 0.3 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 CDO73530.1 - 0.19 12.1 1.1 0.51 10.7 1.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 CDO73530.1 - 0.19 11.8 1.9 0.47 10.5 1.9 1.6 1 0 0 1 1 1 0 Zinc-finger TPR_2 PF07719.17 CDO73530.1 - 0.3 11.3 8.1 2.3 8.6 0.6 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 CDO73530.1 - 0.48 10.3 7.6 0.11 12.4 2.6 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.6 CDO73530.1 - 2.6 7.8 4.1 4.8 6.9 0.2 2.6 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 CDO73530.1 - 5.7 7.4 8.2 2 8.9 0.4 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDO73530.1 - 6.8 6.7 7.4 0.93 9.4 0.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NRDE-2 PF08424.10 CDO73531.1 - 1.3e-31 110.0 5.3 2.8e-31 108.9 5.3 1.5 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference RVT_3 PF13456.6 CDO73534.1 - 0.04 13.7 0.4 0.73 9.7 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like CBM_19 PF03427.13 CDO73536.1 - 3.9e-08 33.2 11.9 0.00091 19.2 4.9 2.7 2 0 0 2 2 2 2 Carbohydrate binding domain (family 19) PocR PF10114.9 CDO73536.1 - 0.0053 16.6 1.0 1.1 9.0 0.1 2.4 2 0 0 2 2 2 2 Sensory domain found in PocR FAD_binding_4 PF01565.23 CDO73536.1 - 0.031 14.0 0.4 6.6 6.5 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain SAM_adeno_trans PF01887.16 CDO73536.1 - 0.075 12.5 0.0 1.2 8.6 0.0 2.1 1 1 1 2 2 2 0 S-adenosyl-l-methionine hydroxide adenosyltransferase CBM_14 PF01607.24 CDO73536.1 - 5.8 7.2 8.1 18 5.6 1.1 3.0 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Utp21 PF04192.12 CDO73537.1 - 1.4e-66 224.3 4.4 2.2e-66 223.7 4.4 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 CDO73537.1 - 1.7e-17 63.5 0.0 5.2e-05 23.5 0.0 7.4 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDO73537.1 - 8.8e-14 51.7 11.6 0.0076 17.1 0.0 8.8 11 0 0 11 11 11 3 WD domain, G-beta repeat Hira PF07569.11 CDO73537.1 - 0.00049 19.9 0.3 0.017 14.9 0.2 3.2 1 1 1 2 2 2 1 TUP1-like enhancer of split Nucleoporin_N PF08801.11 CDO73537.1 - 0.00093 18.0 0.1 1.7 7.3 0.0 4.2 2 2 1 4 4 4 1 Nup133 N terminal like PQQ_2 PF13360.6 CDO73537.1 - 0.0012 18.5 0.1 0.0048 16.5 0.0 2.0 2 0 0 2 2 2 1 PQQ-like domain Utp12 PF04003.12 CDO73537.1 - 0.0014 18.9 1.2 0.003 17.8 1.2 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF3287 PF11690.8 CDO73539.1 - 0.03 14.0 0.4 0.11 12.3 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Gln-synt_C PF00120.24 CDO73541.1 - 2.5e-76 256.9 0.0 5.1e-76 255.9 0.0 1.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF3074 PF11274.8 CDO73542.1 - 1.4e-43 149.1 1.2 1.9e-43 148.6 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.19 CDO73542.1 - 0.00023 20.7 0.1 0.00031 20.2 0.1 1.2 1 0 0 1 1 1 1 START domain F-box-like PF12937.7 CDO73543.1 - 2.4e-05 24.1 0.5 8e-05 22.4 0.5 2.0 1 0 0 1 1 1 1 F-box-like Ribosomal_L27 PF01016.19 CDO73544.1 - 7e-34 115.7 0.5 9.2e-34 115.3 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein mRNA_cap_enzyme PF01331.19 CDO73545.1 - 1.4e-51 175.1 0.2 6.2e-51 173.0 0.1 2.0 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain Skp1 PF01466.19 CDO73545.1 - 1.2e-26 92.5 0.1 3e-26 91.3 0.1 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CDO73545.1 - 8.4e-25 86.7 0.7 3.6e-24 84.7 0.2 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DNA_ligase_A_M PF01068.21 CDO73545.1 - 6.8e-12 45.5 0.0 1.6e-06 28.0 0.0 2.9 2 1 1 3 3 3 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 CDO73545.1 - 9.4e-05 22.8 0.0 0.00016 22.0 0.0 1.4 1 0 0 1 1 1 1 RNA ligase mRNA_cap_C PF03919.15 CDO73545.1 - 0.00015 22.4 0.0 0.00048 20.7 0.0 1.9 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain BTB PF00651.31 CDO73545.1 - 0.033 14.4 0.0 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain Amidohydro_1 PF01979.20 CDO73547.1 - 2e-09 37.2 0.0 2.5e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Lipase_3 PF01764.25 CDO73548.1 - 9.4e-08 32.0 0.0 3.3e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CDO73548.1 - 0.0002 22.1 2.7 0.0005 20.7 0.3 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 CDO73548.1 - 0.0069 16.4 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 CDO73548.1 - 0.076 12.6 0.1 0.31 10.7 0.1 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO73548.1 - 0.18 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDO73548.1 - 0.2 11.4 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein MARVEL PF01284.23 CDO73549.1 - 3.8 7.5 9.5 19 5.3 0.1 2.6 2 1 1 3 3 3 0 Membrane-associating domain CTP_transf_like PF01467.26 CDO73550.1 - 7.3e-05 23.0 0.0 0.00092 19.4 0.0 2.4 2 0 0 2 2 2 1 Cytidylyltransferase-like LIM PF00412.22 CDO73551.1 - 3.7e-11 43.1 11.5 5.9e-06 26.4 2.0 3.2 3 0 0 3 3 3 3 LIM domain WRC PF08879.10 CDO73551.1 - 0.0037 16.9 1.0 2.2 8.1 0.1 3.0 2 0 0 2 2 2 2 WRC CxC6 PF18721.1 CDO73551.1 - 0.18 12.1 6.6 1.1 9.6 1.6 2.4 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases zf_UBZ PF18439.1 CDO73552.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Transposase_21 PF02992.14 CDO73553.1 - 1.2e-08 34.4 0.3 2.4e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 Zn_clus PF00172.18 CDO73555.1 - 1e-09 38.4 4.4 2.1e-09 37.3 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CDO73555.1 - 0.00021 20.4 0.0 0.0018 17.3 0.0 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain FAM176 PF14851.6 CDO73555.1 - 0.8 9.4 3.9 26 4.5 0.4 3.2 3 0 0 3 3 3 0 FAM176 family TFIIA PF03153.13 CDO73555.1 - 2 8.3 25.7 0.32 10.9 7.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Syja_N PF02383.18 CDO73557.1 - 1.7e-84 283.9 0.0 2.7e-84 283.2 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 CDO73557.1 - 1.2e-32 112.1 0.0 2.3e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase Proteasome PF00227.26 CDO73558.1 - 1.4e-49 168.2 0.2 1.7e-49 167.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit UQ_con PF00179.26 CDO73559.1 - 8.3e-49 164.8 0.0 9.4e-49 164.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDO73559.1 - 0.00012 21.8 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Ribosomal_L7Ae PF01248.26 CDO73560.1 - 2.7e-25 87.9 0.0 3.5e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CDO73560.1 - 0.00034 20.4 0.0 0.00052 19.8 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CDO73560.1 - 0.0007 19.7 0.1 0.00082 19.5 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 bZIP_1 PF00170.21 CDO73560.1 - 0.33 11.1 1.5 0.64 10.2 0.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor CDH-cyt PF16010.5 CDO73561.1 - 1.4e-44 152.0 0.0 2.1e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase CBM_1 PF00734.18 CDO73561.1 - 2.3e-09 37.1 6.1 2.3e-09 37.1 6.1 2.1 2 1 0 2 2 2 1 Fungal cellulose binding domain DOMON PF03351.17 CDO73561.1 - 0.0064 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 DOMON domain RVP_2 PF08284.11 CDO73562.1 - 0.091 12.5 0.0 0.88 9.3 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF1713 PF08213.11 CDO73563.1 - 0.0024 17.7 13.6 0.0036 17.2 13.6 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) RhoGEF PF00621.20 CDO73564.1 - 2.7e-14 53.8 0.2 4.3e-14 53.2 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain F-box-like PF12937.7 CDO73565.1 - 2.2e-06 27.4 2.0 1.1e-05 25.2 2.0 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 CDO73565.1 - 0.2 11.6 2.9 1.9 8.5 1.2 2.7 2 0 0 2 2 2 0 F-box domain Glyco_transf_22 PF03901.17 CDO73566.1 - 3e-85 287.0 19.3 3.7e-85 286.7 19.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF572 PF04502.13 CDO73566.1 - 0.0015 18.3 13.8 0.0026 17.4 13.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) Macoilin PF09726.9 CDO73566.1 - 0.28 9.7 6.0 0.4 9.2 6.0 1.1 1 0 0 1 1 1 0 Macoilin family SLY PF12485.8 CDO73566.1 - 8.8 7.0 13.4 2 9.1 9.4 1.9 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein KH_8 PF17903.1 CDO73567.1 - 2.3e-06 27.6 0.0 5.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CDO73567.1 - 0.01 15.7 0.6 0.024 14.4 0.6 1.6 1 0 0 1 1 1 0 KH domain F-box PF00646.33 CDO73568.1 - 4e-05 23.4 0.0 0.00012 21.9 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO73568.1 - 0.0047 16.8 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like FliT PF05400.13 CDO73568.1 - 0.28 12.0 4.4 1 10.2 4.4 2.0 1 1 0 1 1 1 0 Flagellar protein FliT Hemerythrin PF01814.23 CDO73569.1 - 6.9e-09 36.4 7.0 1.2e-08 35.7 7.0 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain VRR_NUC PF08774.11 CDO73570.1 - 4.7e-27 94.2 0.0 1.3e-26 92.8 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain Rho_N PF07498.12 CDO73570.1 - 0.033 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain WD40 PF00400.32 CDO73572.1 - 3.3e-06 27.7 1.6 0.02 15.7 0.5 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO73572.1 - 4.2e-05 23.8 0.0 0.2 12.0 0.0 3.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NOZZLE PF08744.10 CDO73572.1 - 0.081 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Plant transcription factor NOZZLE Glyoxal_oxid_N PF07250.11 CDO73573.1 - 2.3e-33 115.4 0.0 1.9e-32 112.4 0.0 2.3 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CDO73573.1 - 1.6e-21 76.4 0.0 5e-21 74.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) BiPBP_C PF06832.12 CDO73573.1 - 0.046 13.8 0.1 20 5.3 0.0 2.9 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family SKIP_SNW PF02731.15 CDO73574.1 - 1.2e-72 242.8 1.5 1.2e-72 242.8 1.5 2.3 2 0 0 2 2 2 1 SKIP/SNW domain Myc_N PF01056.18 CDO73574.1 - 6.9 6.5 9.5 2.2 8.1 6.5 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Tim54 PF11711.8 CDO73575.1 - 3.2e-61 207.2 0.4 6.2e-60 203.0 0.1 2.3 2 1 0 2 2 2 2 Inner membrane protein import complex subunit Tim54 Sec63 PF02889.16 CDO73576.1 - 1.4e-21 76.9 2.7 8.8e-21 74.2 0.1 2.3 1 1 1 2 2 2 1 Sec63 Brl domain Helicase_C PF00271.31 CDO73576.1 - 3.2e-07 30.7 0.0 2.3e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Beta_protein PF14350.6 CDO73576.1 - 0.016 14.6 0.2 0.03 13.7 0.2 1.3 1 0 0 1 1 1 0 Beta protein Pribosyltran PF00156.27 CDO73576.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain CKS PF01111.19 CDO73577.1 - 8.2e-37 125.3 0.3 1e-36 125.0 0.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF3822 PF12864.7 CDO73577.1 - 0.096 11.9 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) Peptidase_M16_M PF16187.5 CDO73578.1 - 1.2e-97 326.6 0.5 1.2e-96 323.4 0.2 2.2 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CDO73578.1 - 5.8e-39 133.4 2.1 1.8e-38 131.8 0.1 2.5 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDO73578.1 - 7e-24 84.8 0.1 9.7e-15 55.0 0.1 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain HSBP1 PF06825.12 CDO73578.1 - 0.033 14.1 0.2 0.15 11.9 0.4 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 TTRAP PF14203.6 CDO73578.1 - 0.41 10.7 3.2 16 5.6 0.3 2.7 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Rep_fac-A_C PF08646.10 CDO73580.1 - 1.3e-48 164.4 0.3 1.9e-46 157.5 0.1 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CDO73580.1 - 6.6e-39 131.8 0.5 2.8e-37 126.5 0.0 2.5 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 CDO73580.1 - 2.8e-20 72.2 0.1 5.4e-20 71.3 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 CDO73580.1 - 1.1e-14 54.1 0.1 6.9e-13 48.4 0.0 2.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF5521 PF17659.1 CDO73580.1 - 4.4e-05 21.6 0.1 0.0064 14.4 0.0 2.8 3 0 0 3 3 3 1 Family of unknown function (DUF5521) DUF223 PF02721.14 CDO73580.1 - 0.00046 20.4 0.0 0.0027 18.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF223 DUF4539 PF15072.6 CDO73580.1 - 0.00056 19.9 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) CDC24_OB3 PF17244.2 CDO73580.1 - 0.00076 19.3 0.3 0.96 9.1 0.0 3.0 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 zinc-ribbons_6 PF07191.12 CDO73580.1 - 0.017 15.1 1.0 0.051 13.6 1.0 1.8 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.7 CDO73580.1 - 0.08 13.0 1.5 0.16 12.0 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 CDO73580.1 - 0.13 12.2 0.9 0.3 11.0 0.9 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 CDO73580.1 - 0.76 9.4 3.0 2.4 7.8 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger IDO PF01231.18 CDO73581.1 - 1.3e-114 383.3 0.0 1.9e-114 382.8 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ECH_2 PF16113.5 CDO73582.1 - 3.2e-117 391.8 0.0 3.8e-117 391.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CDO73582.1 - 2.1e-20 73.1 0.0 3e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase HEAT_2 PF13646.6 CDO73582.1 - 0.013 15.9 1.6 0.021 15.2 0.4 2.0 2 0 0 2 2 2 0 HEAT repeats VPS13_mid_rpt PF16910.5 CDO73582.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Repeating coiled region of VPS13 PHF12_MRG_bd PF16737.5 CDO73582.1 - 0.014 15.1 0.4 0.032 14.0 0.4 1.5 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain DUF1822 PF08852.11 CDO73582.1 - 0.029 13.4 0.2 0.043 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) DUF5069 PF16798.5 CDO73582.1 - 0.039 14.1 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) CAP_GLY PF01302.25 CDO73583.1 - 1.1e-18 67.0 0.7 2.1e-18 66.1 0.7 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 CDO73583.1 - 1.6e-14 53.8 1.2 0.0022 18.3 0.0 6.2 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDO73583.1 - 2.7e-12 46.2 0.2 0.00049 19.8 0.0 5.5 4 2 0 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 CDO73583.1 - 7.2e-10 38.6 0.0 1.9e-05 24.3 0.0 2.9 2 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 CDO73583.1 - 0.004 17.1 5.5 86 3.6 0.3 7.1 8 0 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 CDO73583.1 - 0.01 16.3 3.5 32 5.6 0.3 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat RRM_1 PF00076.22 CDO73584.1 - 1.6e-31 107.9 0.0 7e-18 64.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDO73584.1 - 3.3e-05 23.9 0.0 0.0011 19.0 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.8 CDO73584.1 - 4.3e-05 23.5 0.1 0.064 13.3 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 Nup35_RRM_2 PF14605.6 CDO73584.1 - 0.00026 20.9 0.0 0.011 15.8 0.0 2.5 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CDO73584.1 - 0.0048 16.5 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CDO73584.1 - 0.0076 16.2 0.0 4.7 7.3 0.0 2.4 2 0 0 2 2 2 2 DbpA RNA binding domain SET_assoc PF11767.8 CDO73584.1 - 0.042 13.5 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Aminotran_5 PF00266.19 CDO73585.1 - 2.3e-95 319.7 0.0 2.7e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CDO73585.1 - 3.8e-08 33.0 0.1 5.2e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CDO73585.1 - 0.00029 20.3 0.1 0.0034 16.7 0.1 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CDO73585.1 - 0.00065 18.3 0.0 0.001 17.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 CDO73585.1 - 0.0035 16.1 0.0 0.0054 15.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Glyco_hydro_6 PF01341.17 CDO73586.1 - 4.6e-107 358.3 2.3 5.6e-107 358.0 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 CDO73586.1 - 6.2e-15 54.8 12.1 1.6e-14 53.6 12.1 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain CHCH PF06747.13 CDO73586.1 - 0.11 12.6 0.3 9.7 6.5 0.1 2.4 2 0 0 2 2 2 0 CHCH domain DUF1681 PF07933.14 CDO73587.1 - 4.8e-51 172.4 0.0 5.6e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Rab_eff_C PF04698.12 CDO73587.1 - 0.044 12.1 0.0 0.044 12.1 0.0 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus CSN8_PSD8_EIF3K PF10075.9 CDO73588.1 - 0.051 13.5 0.2 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family NIF PF03031.18 CDO73589.1 - 2.1e-20 73.0 0.0 3.1e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Aldo_ket_red PF00248.21 CDO73590.1 - 5.1e-68 229.4 0.0 2.1e-65 220.8 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family NUDIX PF00293.28 CDO73591.1 - 6.7e-10 39.1 0.0 5.8e-09 36.1 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain COesterase PF00135.28 CDO73592.1 - 4.6e-61 207.2 0.0 5.8e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDO73592.1 - 1.9e-12 47.5 0.3 3.3e-12 46.7 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold CwfJ_C_1 PF04677.15 CDO73593.1 - 8.8e-30 103.1 0.0 2.1e-29 101.9 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 CDO73593.1 - 2.1e-14 53.0 14.9 2.7e-07 30.3 0.8 3.7 3 0 0 3 3 3 3 Zinc knuckle CwfJ_C_2 PF04676.14 CDO73593.1 - 4.2e-13 50.0 0.0 9.9e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 CDO73593.1 - 6.3e-05 22.9 1.2 0.23 11.6 0.0 3.0 2 0 0 2 2 2 2 Zinc knuckle ANAPC15 PF15243.6 CDO73594.1 - 0.016 15.6 9.4 0.016 15.6 9.4 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 15 DUF2151 PF10221.9 CDO73594.1 - 0.048 12.3 0.1 0.055 12.1 0.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Apc15p PF05841.11 CDO73594.1 - 0.048 14.5 0.1 0.096 13.5 0.0 1.5 1 1 1 2 2 2 0 Apc15p protein Na_trans_assoc PF06512.13 CDO73594.1 - 0.28 11.4 7.5 0.34 11.2 7.5 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2076 PF09849.9 CDO73594.1 - 1.1 9.3 10.6 1.4 8.9 10.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Nop14 PF04147.12 CDO73594.1 - 5.2 5.2 18.1 5.9 5.0 18.1 1.0 1 0 0 1 1 1 0 Nop14-like family Arginase PF00491.21 CDO73595.1 - 2.5e-74 250.3 0.0 3.1e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family Aminotran_1_2 PF00155.21 CDO73596.1 - 1.7e-27 96.5 0.0 7.1e-22 78.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CDO73596.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase MFS_1 PF07690.16 CDO73597.1 - 3.2e-34 118.4 27.2 4.7e-34 117.9 27.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Chitin_synth_2 PF03142.15 CDO73597.1 - 0.28 9.7 0.9 0.47 9.0 0.9 1.2 1 0 0 1 1 1 0 Chitin synthase YrhC PF14143.6 CDO73597.1 - 4.3 7.5 5.8 2.4 8.3 0.2 3.3 3 0 0 3 3 3 0 YrhC-like protein Acyl-CoA_dh_1 PF00441.24 CDO73598.1 - 8.6e-43 146.1 0.2 3.2e-42 144.3 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CDO73598.1 - 3.1e-39 134.1 0.0 5.5e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CDO73598.1 - 5.7e-26 90.6 0.0 1.1e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CDO73598.1 - 4.8e-15 56.0 0.0 4.8e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CDO73598.1 - 0.12 12.0 0.1 0.55 9.9 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Zn_clus PF00172.18 CDO73600.1 - 4.7e-10 39.4 15.3 4.7e-10 39.4 15.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.27 CDO73601.1 - 1.6e-15 56.4 6.1 2.8e-15 55.6 6.1 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 CDO73601.1 - 2.3e-06 27.8 0.0 4.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 CDO73601.1 - 0.0006 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold ZapB PF06005.12 CDO73601.1 - 0.048 14.1 0.0 0.081 13.4 0.0 1.3 1 0 0 1 1 1 0 Cell division protein ZapB PAS_9 PF13426.7 CDO73601.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain bZIP_2 PF07716.15 CDO73601.1 - 0.09 12.9 1.7 0.19 11.8 1.7 1.5 1 0 0 1 1 1 0 Basic region leucine zipper adh_short_C2 PF13561.6 CDO73602.1 - 3.5e-59 200.2 0.1 4.4e-59 199.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO73602.1 - 1.1e-43 148.9 0.2 3.1e-43 147.5 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CDO73602.1 - 1.1e-10 41.7 0.1 2.3e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO73602.1 - 0.00027 20.5 0.0 0.00094 18.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDO73602.1 - 0.0016 17.7 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Kinesin PF00225.23 CDO73603.1 - 1e-97 327.0 0.0 2.7e-56 190.9 0.0 5.0 5 0 0 5 5 5 2 Kinesin motor domain Microtub_bd PF16796.5 CDO73603.1 - 4.4e-23 81.9 0.0 1.9e-22 79.8 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding Fib_alpha PF08702.10 CDO73603.1 - 0.0011 19.2 6.4 0.0019 18.4 2.0 12.9 5 3 4 12 12 12 3 Fibrinogen alpha/beta chain family NTS PF15447.6 CDO73603.1 - 0.19 12.2 1.7 11 6.6 0.1 2.9 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 Phlebovirus_G2 PF07245.11 CDO73603.1 - 0.23 9.9 0.0 0.39 9.2 0.0 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Acetyltransf_1 PF00583.25 CDO73604.1 - 1.7e-08 34.7 0.1 5.7e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDO73604.1 - 4.4e-07 29.9 0.0 5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDO73604.1 - 4.5e-07 30.2 0.0 8.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDO73604.1 - 6.9e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 CDO73604.1 - 0.00024 21.0 0.0 0.00096 19.1 0.0 2.0 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase FR47 PF08445.10 CDO73604.1 - 0.0079 16.1 0.0 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 CDO73604.1 - 0.033 14.9 0.0 0.093 13.4 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDO73604.1 - 0.21 11.7 0.1 0.53 10.4 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.32 CDO73605.1 - 3e-15 56.3 16.2 0.00044 21.0 0.2 7.6 6 1 2 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO73605.1 - 1.3e-09 38.2 0.0 0.022 15.1 0.0 4.4 3 3 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDO73605.1 - 0.015 15.1 0.0 0.56 10.1 0.0 2.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 CDO73605.1 - 0.024 13.4 1.6 0.29 9.8 0.7 2.6 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region BTB PF00651.31 CDO73606.1 - 0.041 14.1 0.0 5.3 7.3 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain zf-CCCH PF00642.24 CDO73606.1 - 0.18 11.8 0.4 2.9 7.9 0.6 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.25 CDO73607.1 - 3.4e-38 131.5 0.0 4.2e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73607.1 - 3.9e-14 52.6 0.0 5e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO73607.1 - 1.2e-06 28.1 0.0 1.6e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like PI3_PI4_kinase PF00454.27 CDO73608.1 - 7.6e-29 101.3 0.9 5.6e-18 65.7 0.6 2.6 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CDO73608.1 - 2.3e-22 79.3 0.0 6.8e-22 77.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 CDO73608.1 - 0.078 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RdRP PF05183.12 CDO73610.1 - 4.9e-140 468.0 0.0 2.4e-139 465.7 0.0 2.0 1 1 1 2 2 2 1 RNA dependent RNA polymerase MazG PF03819.17 CDO73610.1 - 0.11 12.8 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Glyco_transf_6 PF03414.13 CDO73610.1 - 0.17 10.7 0.1 0.28 9.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 Peptidase_M28 PF04389.17 CDO73611.1 - 4.2e-08 33.1 0.0 5.9e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M28 Oxidored_FMN PF00724.20 CDO73612.1 - 7.7e-98 327.9 0.0 9.7e-98 327.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PTPRCAP PF15713.5 CDO73613.1 - 0.0098 16.2 3.3 0.015 15.6 0.2 2.0 2 0 0 2 2 2 1 Protein tyrosine phosphatase receptor type C-associated DUF2408 PF10303.9 CDO73613.1 - 0.15 12.7 2.2 0.19 12.3 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HORMA PF02301.18 CDO73614.1 - 1.2e-29 103.4 0.0 1.8e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 HORMA domain MarR PF01047.22 CDO73614.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 MarR family PHD PF00628.29 CDO73614.1 - 0.027 14.4 14.5 0.052 13.4 14.6 1.5 1 0 0 1 1 1 0 PHD-finger PFU PF09070.11 CDO73615.1 - 4.2e-44 149.4 0.0 8.8e-44 148.4 0.0 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 CDO73615.1 - 1.5e-32 113.0 0.0 2.2e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 CDO73615.1 - 9.1e-26 89.6 12.8 8.1e-06 26.5 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 CDO73615.1 - 0.0014 18.6 0.0 1 9.4 0.0 3.0 1 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Na_Ca_ex PF01699.24 CDO73616.1 - 7.8e-32 110.3 41.1 7.7e-21 74.6 13.4 3.0 3 1 0 3 3 3 2 Sodium/calcium exchanger protein AhpC-TSA_2 PF13911.6 CDO73617.1 - 6.2e-18 65.0 0.0 9.7e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 CDO73617.1 - 0.00078 19.4 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family His_Phos_1 PF00300.22 CDO73618.1 - 3e-34 118.4 4.0 3.6e-28 98.6 2.4 3.1 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DMRL_synthase PF00885.19 CDO73619.1 - 4.4e-52 175.7 0.1 8.2e-52 174.8 0.1 1.4 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Gtr1_RagA PF04670.12 CDO73619.1 - 1.3e-50 171.9 0.0 1.9e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRP40_C PF05022.12 CDO73620.1 - 9e-29 100.2 1.9 9e-29 100.2 1.9 2.8 3 1 0 3 3 3 1 SRP40, C-terminal domain ATP_bind_3 PF01171.20 CDO73621.1 - 9e-40 136.4 0.0 1.5e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 PP-loop family YTH PF04146.15 CDO73622.1 - 3.8e-40 137.5 0.6 9.4e-40 136.3 0.0 2.0 2 0 0 2 2 2 1 YT521-B-like domain WD40 PF00400.32 CDO73623.1 - 1.3e-53 177.8 3.0 5.9e-11 42.7 0.1 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO73623.1 - 9.8e-20 70.7 0.8 1.1e-07 32.1 0.0 5.9 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDO73623.1 - 1.6e-08 33.7 4.6 0.027 13.1 0.0 5.1 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CDO73623.1 - 2.2e-05 23.4 0.4 1.9 7.1 0.0 3.9 2 1 2 4 4 4 3 Nup133 N terminal like eIF2A PF08662.11 CDO73623.1 - 0.00016 21.6 0.0 0.1 12.5 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDO73623.1 - 0.002 17.2 1.5 11 4.9 0.1 4.0 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 CDO73623.1 - 0.019 13.9 0.6 0.56 9.1 0.0 2.8 2 2 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain LisH PF08513.11 CDO73623.1 - 0.021 14.7 0.4 0.037 14.0 0.4 1.4 1 0 0 1 1 1 0 LisH ADIP PF11559.8 CDO73623.1 - 0.09 12.9 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3906 PF13046.6 CDO73623.1 - 0.13 12.3 0.2 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) bZIP_2 PF07716.15 CDO73623.1 - 2.2 8.4 5.3 0.19 11.8 0.6 1.6 2 0 0 2 2 2 0 Basic region leucine zipper OPT PF03169.15 CDO73624.1 - 1.8e-143 479.5 47.4 2e-143 479.3 47.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein WD40 PF00400.32 CDO73625.1 - 0.036 15.0 0.2 6.8 7.7 0.4 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat Transketolase_C PF02780.20 CDO73626.1 - 8.8e-26 90.2 0.0 4e-25 88.1 0.0 2.1 2 1 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 CDO73626.1 - 8e-25 87.5 1.4 2e-18 66.7 0.7 2.2 1 1 1 2 2 2 2 Transketolase, pyrimidine binding domain CCER1 PF15482.6 CDO73626.1 - 0.13 12.2 0.2 0.2 11.5 0.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 F-box PF00646.33 CDO73627.1 - 7e-06 25.8 0.3 0.00015 21.6 0.0 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CDO73627.1 - 0.011 15.6 1.1 0.095 12.6 0.1 2.7 2 0 0 2 2 2 0 F-box-like HSF_DNA-bind PF00447.17 CDO73628.1 - 1.1e-30 106.1 0.6 2e-30 105.2 0.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Filament PF00038.21 CDO73628.1 - 0.14 11.7 2.6 0.091 12.3 0.4 1.7 2 0 0 2 2 2 0 Intermediate filament protein POT1PC PF16686.5 CDO73630.1 - 9.8e-28 97.0 1.1 1.3e-12 47.9 0.1 6.2 4 2 0 4 4 4 3 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 CDO73630.1 - 1.4e-11 44.5 0.0 3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 TAP42 PF04177.12 CDO73631.1 - 9.2e-89 297.7 3.9 1e-88 297.5 3.9 1.0 1 0 0 1 1 1 1 TAP42-like family GMC_oxred_C PF05199.13 CDO73631.1 - 0.093 13.2 0.1 0.3 11.6 0.1 1.8 1 0 0 1 1 1 0 GMC oxidoreductase RuvA_C PF07499.13 CDO73631.1 - 0.63 10.6 4.3 0.6 10.6 0.7 2.5 2 0 0 2 2 2 0 RuvA, C-terminal domain Ras PF00071.22 CDO73632.1 - 2e-59 199.9 0.3 2.3e-59 199.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO73632.1 - 1.1e-36 125.7 0.1 2.2e-36 124.7 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO73632.1 - 2.3e-15 56.5 0.1 2.9e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDO73632.1 - 2.1e-06 27.3 0.3 2.6e-06 27.0 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CDO73632.1 - 2.4e-06 27.1 0.1 4e-06 26.4 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CDO73632.1 - 2.5e-06 27.2 0.2 2.9e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDO73632.1 - 4.7e-06 26.6 0.1 0.0034 17.3 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDO73632.1 - 1.4e-05 25.1 0.0 5.1e-05 23.3 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDO73632.1 - 0.00027 20.5 0.3 0.024 14.2 0.3 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B CPT PF07931.12 CDO73632.1 - 0.0026 17.6 0.1 0.059 13.2 0.0 2.4 1 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.9 CDO73632.1 - 0.015 15.0 0.7 0.1 12.4 0.7 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 CDO73632.1 - 0.016 14.6 0.0 0.16 11.4 0.0 2.3 3 0 0 3 3 3 0 Bacterial TniB protein Dynamin_N PF00350.23 CDO73632.1 - 0.033 14.3 0.1 2.4 8.2 0.0 2.7 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 CDO73632.1 - 0.15 12.4 0.0 0.23 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MTHFR PF02219.17 CDO73633.1 - 1.3e-106 356.2 0.0 1.7e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase P_proprotein PF01483.20 CDO73634.1 - 3.8e-28 97.3 0.6 7.5e-28 96.4 0.6 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8 PF00082.22 CDO73634.1 - 4.8e-24 85.1 1.2 2.1e-22 79.8 0.3 2.2 1 1 1 2 2 2 2 Subtilase family MCM PF00493.23 CDO73635.1 - 8.4e-105 348.8 0.0 1.5e-104 348.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CDO73635.1 - 1.3e-19 70.4 2.9 3.4e-19 69.0 2.9 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CDO73635.1 - 1.4e-16 61.0 0.8 4.2e-16 59.4 0.8 1.9 1 0 0 1 1 1 1 MCM N-terminal domain MCM_OB PF17207.3 CDO73635.1 - 1.7e-16 60.2 0.1 3.5e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 CDO73635.1 - 9.9e-08 31.6 0.0 9.8e-06 25.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDO73635.1 - 1.5e-07 31.5 0.0 2.1e-06 27.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 CDO73635.1 - 0.0053 17.4 1.7 0.0053 17.4 1.7 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 CDO73635.1 - 0.028 14.3 0.0 0.094 12.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) VirB8 PF04335.13 CDO73635.1 - 0.13 12.1 0.2 0.3 10.9 0.2 1.5 1 0 0 1 1 1 0 VirB8 protein BAH PF01426.18 CDO73636.1 - 6.8e-17 61.5 0.0 3.3e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 BAH domain DNA_methylase PF00145.17 CDO73636.1 - 0.0049 16.3 0.1 0.0067 15.8 0.1 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF4290 PF14123.6 CDO73636.1 - 0.13 11.8 0.0 0.5 9.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4290) Thiamine_BP PF01910.17 CDO73637.1 - 1.8e-18 66.3 0.0 1.7e-17 63.1 0.0 2.0 1 1 0 1 1 1 1 Thiamine-binding protein PAP_PilO PF06864.12 CDO73637.1 - 0.039 12.8 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Arm PF00514.23 CDO73638.1 - 4e-13 48.9 4.5 8.2e-09 35.2 0.0 5.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CDO73638.1 - 1.1e-05 25.7 16.9 0.47 10.9 0.2 7.4 4 1 2 7 7 7 3 HEAT repeats DUF3361 PF11841.8 CDO73638.1 - 1.8e-05 24.7 4.7 0.00017 21.5 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3361) HEAT_EZ PF13513.6 CDO73638.1 - 4.2e-05 24.0 16.4 0.017 15.6 0.1 6.9 6 2 1 7 7 7 2 HEAT-like repeat Cnd1 PF12717.7 CDO73638.1 - 0.00016 21.8 7.9 0.59 10.2 0.0 4.6 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CDO73638.1 - 0.0072 14.9 11.4 0.019 13.6 1.1 5.1 3 1 2 6 6 6 2 Adaptin N terminal region HEAT PF02985.22 CDO73638.1 - 0.0078 16.4 21.7 0.88 10.0 0.1 8.3 9 0 0 9 9 9 1 HEAT repeat CLASP_N PF12348.8 CDO73638.1 - 0.011 15.3 0.1 0.12 11.9 0.0 2.4 2 0 0 2 2 2 0 CLASP N terminal DUF3636 PF12331.8 CDO73638.1 - 0.012 15.5 1.6 3.3 7.5 0.0 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF3636) E1_dh PF00676.20 CDO73639.1 - 2.8e-112 374.5 0.0 3.4e-112 374.3 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CDO73639.1 - 0.00055 19.2 0.0 0.00093 18.5 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 CDO73639.1 - 0.0016 18.3 1.0 0.0035 17.1 1.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Coa1 PF08695.10 CDO73640.1 - 6.4e-32 109.7 0.0 7.7e-32 109.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 COG6 PF06419.11 CDO73641.1 - 8.9e-137 456.9 0.0 1.5e-135 452.9 0.0 2.6 2 1 0 2 2 2 1 Conserved oligomeric complex COG6 HSF_DNA-bind PF00447.17 CDO73641.1 - 4.1e-25 88.2 0.2 1e-24 86.9 0.2 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1409 PF07197.12 CDO73641.1 - 0.0033 17.3 0.7 0.92 9.4 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1409) DUF1664 PF07889.12 CDO73641.1 - 0.085 12.9 0.4 0.34 11.0 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Filament PF00038.21 CDO73641.1 - 0.16 11.6 2.2 7.4 6.0 0.1 2.5 2 0 0 2 2 2 0 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 CDO73641.1 - 3.3 7.9 8.0 1.4 9.1 2.3 2.9 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 KxDL PF10241.9 CDO73641.1 - 5.9 7.2 5.4 8.3 6.8 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein Arrestin_C PF02752.22 CDO73642.1 - 4.9e-08 33.5 0.4 3.4e-07 30.8 0.1 2.5 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CDO73642.1 - 0.029 14.4 0.0 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CDO73642.1 - 0.1 12.3 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Arrestin_N terminal like Tugs PF17840.1 CDO73642.1 - 0.15 12.3 0.3 23 5.3 0.1 2.6 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain APG9 PF04109.16 CDO73643.1 - 7.9e-194 645.1 11.0 1.2e-183 611.6 4.4 2.0 1 1 1 2 2 2 2 Autophagy protein Apg9 DUF3808 PF10300.9 CDO73644.1 - 2.5e-60 204.6 0.0 4.6e-48 164.1 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_19 PF14559.6 CDO73644.1 - 5.8e-07 29.9 1.8 4.5e-06 27.1 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDO73644.1 - 2.8e-06 27.0 0.3 0.83 9.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDO73644.1 - 0.00015 22.3 1.3 0.0088 16.7 0.0 3.5 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDO73644.1 - 0.0024 18.5 4.8 6.2 7.9 0.2 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO73644.1 - 0.0079 16.4 0.1 0.022 15.0 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CDO73644.1 - 0.0088 16.0 1.0 6.1 7.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDO73644.1 - 0.02 14.7 0.0 3.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDO73644.1 - 0.045 14.4 1.2 29 5.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDO73644.1 - 0.063 13.6 0.4 10 6.5 0.4 3.3 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDO73644.1 - 0.18 12.1 1.5 2.3 8.6 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat SPX PF03105.19 CDO73645.1 - 5.2 6.9 5.0 6.2 6.6 5.0 1.1 1 0 0 1 1 1 0 SPX domain CoaE PF01121.20 CDO73646.1 - 3.9e-08 33.2 0.2 5.3e-08 32.7 0.2 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase LSM14 PF12701.7 CDO73647.1 - 5.8e-25 87.2 0.0 1.2e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CDO73647.1 - 1.8e-10 41.6 2.4 1.8e-10 41.6 2.4 2.2 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 CDO73647.1 - 0.00015 21.9 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.13 CDO73647.1 - 0.0021 18.1 10.4 0.0026 17.9 10.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CDO73647.1 - 3.6 5.7 8.9 4.7 5.3 8.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tyr_Deacylase PF02580.16 CDO73648.1 - 2.8e-32 112.2 0.0 3.5e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.21 CDO73649.1 - 9.1e-42 143.0 0.0 1.1e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CDO73650.1 - 1.5e-31 108.0 22.5 6.5e-06 26.8 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 CDO73650.1 - 1.7e-13 50.3 1.6 1.7e-13 50.3 1.6 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDO73650.1 - 4.4e-11 42.4 0.6 4.4e-11 42.4 0.6 2.8 2 1 1 3 3 3 1 F-box domain Nup160 PF11715.8 CDO73650.1 - 1.6e-08 33.7 5.6 0.0039 15.9 0.0 4.8 4 1 0 5 5 5 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CDO73650.1 - 3.2e-05 24.2 0.1 4.2 7.7 0.0 4.4 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CDO73650.1 - 0.0011 18.6 1.9 0.19 11.3 0.4 2.3 2 0 0 2 2 2 2 PQQ-like domain PALB2_WD40 PF16756.5 CDO73650.1 - 1.6 7.6 4.6 2.9 6.7 0.1 2.6 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Fungal_trans PF04082.18 CDO73651.1 - 1e-17 64.1 0.2 1.6e-17 63.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 CDO73652.1 - 1.6e-07 31.2 0.0 4.6e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO73652.1 - 5.1e-07 29.7 0.0 9.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 CDO73652.1 - 0.0092 16.2 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 CDO73652.1 - 0.031 13.6 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 CDO73652.1 - 0.048 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase E1-N PF14463.6 CDO73652.1 - 0.05 13.4 0.1 0.079 12.8 0.1 1.3 1 0 0 1 1 1 0 E1 N-terminal domain adh_short PF00106.25 CDO73652.1 - 0.091 12.2 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase PWWP PF00855.17 CDO73653.1 - 0.00052 20.4 0.3 0.018 15.4 0.0 2.9 3 0 0 3 3 3 1 PWWP domain GDA1_CD39 PF01150.17 CDO73654.1 - 6.5e-99 331.5 0.0 5.6e-98 328.4 0.0 1.9 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CDO73654.1 - 0.0082 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Rab5ip PF07019.12 CDO73654.1 - 0.061 13.9 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Radical_SAM_C PF16199.5 CDO73655.1 - 3.7e-30 103.8 0.0 7.1e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CDO73655.1 - 6.7e-15 55.9 1.0 4.6e-14 53.1 0.3 2.6 2 1 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CDO73655.1 - 3.5e-11 43.4 0.2 6.8e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDO73655.1 - 2.7e-06 27.3 0.0 6.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDO73655.1 - 0.0026 18.2 0.2 0.014 15.8 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDO73655.1 - 0.073 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein MMM1 PF10296.9 CDO73656.1 - 4.6e-13 48.9 0.0 2.1e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 C1ORF64 PF15547.6 CDO73656.1 - 0.093 13.2 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein Nuc_sug_transp PF04142.15 CDO73657.1 - 1.3e-91 307.1 8.6 1.8e-91 306.6 8.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 CDO73657.1 - 0.0012 18.2 2.6 0.0012 18.2 2.6 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 CDO73657.1 - 0.0022 18.1 7.4 0.0022 18.1 7.4 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CDO73657.1 - 0.011 15.0 12.2 0.096 11.9 12.2 2.0 1 1 0 1 1 1 0 UAA transporter family DUF4231 PF14015.6 CDO73657.1 - 7.6 7.1 10.3 2 8.9 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Mit_ribos_Mrp51 PF11709.8 CDO73658.1 - 8.5e-14 51.9 1.9 2e-13 50.7 1.9 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit EFhand_Ca_insen PF08726.10 CDO73659.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Ca2+ insensitive EF hand UPF1_Zn_bind PF09416.10 CDO73660.1 - 1.8e-69 232.6 2.0 1.8e-69 232.6 2.0 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CDO73660.1 - 2.5e-59 200.2 0.0 4.3e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDO73660.1 - 1.2e-51 176.1 3.6 2e-30 106.5 0.6 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CDO73660.1 - 7.5e-37 125.5 0.0 1.5e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CDO73660.1 - 8.9e-15 54.9 0.1 1.5e-13 50.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CDO73660.1 - 8.8e-12 45.6 0.1 2.5e-11 44.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CDO73660.1 - 6.5e-07 29.3 0.0 0.046 13.5 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CDO73660.1 - 6.7e-06 25.6 0.0 0.0002 20.7 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 CDO73660.1 - 1.8e-05 24.8 0.0 3.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 CDO73660.1 - 0.00044 20.1 0.0 0.00094 19.1 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 CDO73660.1 - 0.00079 19.0 0.1 0.013 15.1 0.1 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Ribosomal_S13_N PF08069.12 CDO73660.1 - 0.0072 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain AAA_10 PF12846.7 CDO73660.1 - 0.02 13.9 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PIF1 PF05970.14 CDO73660.1 - 0.02 14.0 0.1 0.74 8.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 CDO73660.1 - 0.039 14.2 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDO73660.1 - 0.039 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 CDO73660.1 - 0.052 13.0 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 CDO73660.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC Ribosomal_S27e PF01667.17 CDO73660.1 - 0.076 12.7 0.5 0.24 11.1 0.5 1.8 1 0 0 1 1 1 0 Ribosomal protein S27 DEAD PF00270.29 CDO73660.1 - 0.093 12.5 0.4 0.21 11.4 0.3 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.6 CDO73660.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CDO73660.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 CDO73660.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-UBP PF02148.19 CDO73660.1 - 3.3 8.1 5.8 11 6.4 5.8 2.0 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Lipase_GDSL PF00657.22 CDO73661.1 - 0.00016 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Adap_comp_sub PF00928.21 CDO73662.1 - 2.3e-84 282.9 0.1 2.8e-84 282.6 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDO73662.1 - 1.1e-07 31.9 1.5 1.9e-07 31.1 1.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CDO73662.1 - 0.0074 15.8 0.2 0.013 14.9 0.2 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain DUF5618 PF18498.1 CDO73662.1 - 0.027 14.7 0.3 0.091 13.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) DUF11 PF01345.18 CDO73662.1 - 4.7 7.6 6.5 1.5 9.2 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF11 CENP-C_C PF11699.8 CDO73663.1 - 7.8e-23 80.5 3.4 7.5e-19 67.7 0.7 2.3 2 0 0 2 2 2 2 Mif2/CENP-C like Cupin_2 PF07883.11 CDO73663.1 - 0.0094 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 CDO73663.1 - 0.045 13.4 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF4554 PF15091.6 CDO73663.1 - 0.79 8.5 2.4 1.3 7.8 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) PAP_assoc PF03828.19 CDO73664.1 - 9.3e-17 61.0 0.1 2.1e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CDO73664.1 - 7.7e-08 32.5 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain SAPS PF04499.15 CDO73666.1 - 4.6e-128 428.1 0.0 7.3e-128 427.4 0.0 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein tRNA_Me_trans PF03054.16 CDO73666.1 - 7.6e-77 258.5 0.0 1.1e-76 257.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase FAA_hydrolase PF01557.18 CDO73667.1 - 2.5e-58 197.3 0.0 3.1e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TPP_enzyme_C PF02775.21 CDO73669.1 - 7.2e-44 149.3 0.2 1.8e-43 148.0 0.2 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 CDO73669.1 - 4.3e-42 143.7 0.4 9.2e-42 142.6 0.2 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CDO73669.1 - 9.8e-25 86.9 0.1 5.8e-24 84.4 0.1 2.3 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 CDO73672.1 - 3e-16 59.6 1.6 5.3e-16 58.8 1.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO73672.1 - 5e-07 30.8 0.8 2e-06 28.9 0.8 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.10 CDO73672.1 - 0.032 14.4 0.8 0.1 12.8 0.3 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Choline_transpo PF04515.12 CDO73673.1 - 3.1e-26 92.4 20.6 3.7e-21 75.7 3.9 3.5 2 2 1 3 3 3 2 Plasma-membrane choline transporter AP3D1 PF06375.11 CDO73674.1 - 0.0041 17.4 2.3 0.011 16.0 2.3 1.8 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 G-alpha PF00503.20 CDO73675.1 - 1.1e-67 228.7 0.0 1.4e-66 225.1 0.0 1.9 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDO73675.1 - 0.0015 18.0 0.0 0.029 13.8 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 CDO73675.1 - 0.1 12.4 0.0 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein La PF05383.17 CDO73676.1 - 8.8e-20 70.5 0.0 1.6e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 La domain adh_short PF00106.25 CDO73677.1 - 5e-16 58.7 0.1 6.6e-11 42.0 0.2 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO73677.1 - 2.6e-06 27.2 0.1 0.0001 22.0 0.0 2.5 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO73677.1 - 1.3e-05 25.2 0.1 2.2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 CDO73677.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CDO73677.1 - 0.024 15.1 0.0 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding ADH_zinc_N PF00107.26 CDO73677.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ATHILA PF03078.15 CDO73677.1 - 0.079 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family Epimerase PF01370.21 CDO73677.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CDO73677.1 - 0.16 12.2 0.1 0.45 10.8 0.1 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AdoHcyase PF05221.17 CDO73679.1 - 2.5e-135 450.4 0.0 2e-74 250.5 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CDO73679.1 - 1e-85 285.7 0.9 1.5e-85 285.2 0.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CDO73679.1 - 1.4e-09 37.5 0.0 2.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CDO73679.1 - 1.6e-05 24.5 0.2 2.6e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CDO73679.1 - 0.0025 18.1 0.1 0.0056 16.9 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.21 CDO73679.1 - 0.034 13.9 0.1 0.054 13.2 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.17 CDO73679.1 - 0.035 14.7 0.3 0.082 13.5 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 CDO73679.1 - 0.041 14.3 0.1 0.093 13.2 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 CDO73679.1 - 0.12 12.4 0.3 0.22 11.6 0.3 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase APG6_N PF17675.1 CDO73680.1 - 0.042 14.4 0.4 0.072 13.6 0.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region GIT1_C PF12205.8 CDO73680.1 - 0.049 13.7 0.2 0.079 13.1 0.2 1.2 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term GAS PF13851.6 CDO73680.1 - 0.069 12.5 1.5 0.097 12.0 1.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Helo_like_N PF17111.5 CDO73680.1 - 0.2 11.0 0.1 0.29 10.5 0.1 1.1 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Apt1 PF10351.9 CDO73680.1 - 0.22 10.3 0.9 0.4 9.5 0.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain PspB PF06667.12 CDO73680.1 - 0.36 10.9 1.6 0.62 10.2 1.6 1.3 1 0 0 1 1 1 0 Phage shock protein B GST_N PF02798.20 CDO73681.1 - 7.2e-10 39.1 0.0 1.4e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CDO73681.1 - 1.6e-08 34.9 0.0 3.1e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO73681.1 - 0.00023 21.1 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO73681.1 - 0.00054 20.1 0.0 0.00086 19.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDO73681.1 - 0.0019 18.4 0.0 0.0029 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CDO73681.1 - 0.033 14.5 0.1 0.21 11.9 0.1 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RT_RNaseH PF17917.1 CDO73682.1 - 0.042 14.1 0.1 0.071 13.4 0.1 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Img2 PF05046.14 CDO73682.1 - 0.07 13.4 0.4 2.5 8.5 0.1 2.3 1 1 1 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) DUF1664 PF07889.12 CDO73682.1 - 0.077 13.0 0.6 0.2 11.7 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FH2 PF02181.23 CDO73682.1 - 0.12 11.5 1.0 0.18 10.9 1.0 1.3 1 1 0 1 1 1 0 Formin Homology 2 Domain Prominin PF05478.11 CDO73682.1 - 0.35 8.8 4.3 0.41 8.5 4.3 1.1 1 0 0 1 1 1 0 Prominin DUF812 PF05667.11 CDO73682.1 - 0.37 9.6 4.9 0.43 9.4 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TolA_bind_tri PF16331.5 CDO73682.1 - 1.4 9.0 6.9 0.38 10.9 0.8 2.7 3 0 0 3 3 3 0 TolA binding protein trimerisation IBR PF01485.21 CDO73683.1 - 1.7e-15 56.9 28.7 1.1e-08 35.2 6.5 3.7 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain RRM_1 PF00076.22 CDO73683.1 - 1.6e-08 34.3 0.0 0.00019 21.2 0.0 4.2 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_UBOX PF13445.6 CDO73683.1 - 1.7e-06 27.9 3.4 1.7e-06 27.9 3.4 3.8 4 1 0 4 4 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDO73683.1 - 5e-06 26.3 0.7 5e-06 26.3 0.7 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO73683.1 - 9e-06 25.5 2.1 9e-06 25.5 2.1 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDO73683.1 - 9.5e-05 22.5 4.0 9.5e-05 22.5 4.0 3.8 3 1 1 4 4 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CDO73683.1 - 0.00065 19.5 2.6 0.00065 19.5 2.6 4.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO73683.1 - 0.00091 19.5 2.2 0.00091 19.5 2.2 4.5 3 1 2 5 5 1 1 Ring finger domain zf-RING_5 PF14634.6 CDO73683.1 - 0.0023 17.9 3.4 0.0023 17.9 3.4 3.7 3 1 1 4 4 3 1 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 CDO73683.1 - 2.4 8.3 22.5 3 7.9 0.1 3.5 2 1 1 3 3 3 0 Transposase zinc-binding domain PHD20L1_u1 PF16660.5 CDO73683.1 - 2.9 8.7 7.8 19 6.1 3.6 2.7 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 TFIIA PF03153.13 CDO73684.1 - 0.76 9.7 44.7 0.013 15.5 30.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3915 PF13054.6 CDO73684.1 - 5.4 7.0 4.3 28 4.7 4.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) GHMP_kinases_N PF00288.26 CDO73684.1 - 6 7.2 7.8 5.2 7.4 0.1 2.3 2 0 0 2 2 2 0 GHMP kinases N terminal domain RRF PF01765.19 CDO73685.1 - 6.5e-19 68.5 12.0 7.5e-19 68.3 0.3 2.2 1 1 1 2 2 2 2 Ribosome recycling factor CooT PF10133.9 CDO73685.1 - 0.058 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT DUF1323 PF07037.11 CDO73685.1 - 0.065 13.6 3.1 3.7 8.0 0.2 2.6 2 1 1 3 3 3 0 Putative transcription regulator (DUF1323) Mito_carr PF00153.27 CDO73686.1 - 1.2e-21 76.5 0.2 2.9e-20 72.0 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Glyco_hydro_16 PF00722.21 CDO73687.1 - 0.0006 19.3 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 CDO73688.1 - 1.5e-05 24.5 0.0 3.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 CDO73689.1 - 0.0015 18.1 0.0 0.0039 16.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 AidB_N PF18158.1 CDO73690.1 - 3.6e-18 66.0 0.1 1.1e-17 64.4 0.0 1.8 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 CDO73690.1 - 1.9e-12 47.7 3.2 3.9e-12 46.6 1.9 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 CDO73690.1 - 0.00057 20.2 0.3 0.0013 19.0 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1691 PF07950.11 CDO73690.1 - 0.055 14.2 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) ATP19 PF11022.8 CDO73692.1 - 1.6e-23 82.8 0.6 1.9e-23 82.6 0.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Phage_holin_3_6 PF07332.11 CDO73692.1 - 0.094 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TPD52 PF04201.15 CDO73693.1 - 0.0035 17.0 1.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Tumour protein D52 family PKcGMP_CC PF16808.5 CDO73693.1 - 0.1 12.4 0.6 0.18 11.7 0.6 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Git3 PF11710.8 CDO73695.1 - 5.9e-08 32.7 4.2 1.1e-07 31.8 4.2 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 CDO73695.1 - 4.6e-05 22.7 2.6 7.3e-05 22.0 2.6 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor ADH_N PF08240.12 CDO73696.1 - 6.5e-25 87.1 1.5 6.5e-25 87.1 1.5 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO73696.1 - 1.5e-21 76.7 1.4 2.5e-21 76.0 1.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO73696.1 - 1e-09 39.5 0.3 2.6e-09 38.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CDO73696.1 - 0.00044 19.8 2.6 0.00065 19.2 2.6 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CDO73696.1 - 0.013 14.9 3.9 0.013 14.9 3.9 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 CDO73696.1 - 0.054 14.2 0.1 0.1 13.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CDO73696.1 - 0.072 12.4 0.2 0.15 11.4 0.2 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CoA_binding PF02629.19 CDO73696.1 - 0.27 11.9 2.6 1.8 9.3 0.6 2.5 2 0 0 2 2 2 0 CoA binding domain G-alpha PF00503.20 CDO73698.1 - 8.2e-104 347.5 0.0 7.9e-103 344.3 0.0 1.9 1 1 0 1 1 1 1 G-protein alpha subunit FA_desaturase PF00487.24 CDO73699.1 - 1e-15 58.3 28.3 1.9e-15 57.4 28.3 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CDO73699.1 - 3.1e-14 52.9 0.0 6.2e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_C48 PF02902.19 CDO73700.1 - 3.1e-05 23.9 0.0 9.2e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain gag-asp_proteas PF13975.6 CDO73702.1 - 0.00061 20.3 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO73702.1 - 0.0049 17.5 0.0 0.01 16.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Bim_N PF06773.11 CDO73702.1 - 0.049 13.3 0.4 0.049 13.3 0.4 2.5 2 0 0 2 2 2 0 Bim protein N-terminus Integrase_H2C2 PF17921.1 CDO73703.1 - 6.7e-11 42.1 0.1 1.7e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CDO73703.1 - 8.9e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO73703.1 - 3.3e-07 30.6 0.0 7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDO73703.1 - 2.2e-05 24.6 0.1 6.9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CDO73703.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 DDE domain CAML PF14963.6 CDO73704.1 - 0.17 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand LRV PF01816.17 CDO73705.1 - 0.00086 19.5 1.1 3 8.4 0.1 3.6 2 0 0 2 2 2 2 Leucine rich repeat variant Mac PF12464.8 CDO73705.1 - 0.0028 17.8 0.0 4.5 7.6 0.0 2.6 2 0 0 2 2 2 2 Maltose acetyltransferase DUF2294 PF10057.9 CDO73705.1 - 0.0043 17.2 0.0 3.3 7.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2294) TusA PF01206.17 CDO73705.1 - 0.0086 15.9 0.0 5.6 6.9 0.0 2.4 2 0 0 2 2 2 2 Sulfurtransferase TusA MBT PF02820.18 CDO73705.1 - 0.018 15.4 0.0 10 6.6 0.0 2.5 2 0 0 2 2 2 0 mbt repeat YfbU PF03887.14 CDO73705.1 - 0.14 12.2 0.0 20 5.1 0.0 2.3 2 0 0 2 2 2 0 YfbU domain GSHPx PF00255.19 CDO73706.1 - 1.3e-39 134.1 0.1 3e-38 129.7 0.1 2.1 1 1 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CDO73706.1 - 1.5e-05 24.9 0.0 4.4e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDO73706.1 - 0.002 17.9 0.0 0.0061 16.3 0.0 1.8 1 1 0 1 1 1 1 Redoxin Asp PF00026.23 CDO73707.1 - 3.7e-34 118.6 0.0 3.6e-25 89.0 0.1 2.2 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Retrotran_gag_2 PF14223.6 CDO73707.1 - 1.2e-12 47.7 0.0 7.4e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type TAXi_N PF14543.6 CDO73707.1 - 1.6e-10 41.5 1.6 2e-09 37.9 1.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Metallophos PF00149.28 CDO73708.1 - 6.6e-11 43.1 0.0 1.3e-10 42.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase GFO_IDH_MocA PF01408.22 CDO73710.1 - 2.5e-22 79.9 0.0 3.8e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.16 CDO73710.1 - 0.05 14.3 0.0 0.16 12.7 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.24 CDO73710.1 - 0.14 12.6 0.0 0.42 11.1 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Hydrolase_4 PF12146.8 CDO73711.1 - 1.1e-41 142.7 0.0 1.3e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO73711.1 - 9e-13 49.3 1.2 1.2e-12 49.0 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDO73711.1 - 7.8e-10 38.8 0.0 1.8e-06 27.8 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 CDO73711.1 - 1.7e-05 23.7 0.8 0.14 10.8 0.4 3.0 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 CDO73711.1 - 0.0024 17.8 0.0 0.0078 16.1 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDO73711.1 - 0.011 15.2 0.1 0.39 10.2 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 CDO73711.1 - 0.05 13.1 0.0 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF155 PF02582.14 CDO73712.1 - 5.5e-48 163.4 0.0 8.1e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 NUDE_C PF04880.13 CDO73712.1 - 2 8.8 8.6 0.067 13.7 2.1 1.8 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region SNF5 PF04855.12 CDO73713.1 - 1.5e-73 247.5 0.0 4e-73 246.1 0.0 1.6 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 RNase_HII PF01351.18 CDO73713.1 - 1.1e-45 155.9 0.0 1.4e-37 129.5 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease HII SART-1 PF03343.13 CDO73714.1 - 2.9e-165 551.4 60.6 3.4e-164 547.9 56.9 2.0 2 0 0 2 2 2 2 SART-1 family Arg_tRNA_synt_N PF03485.16 CDO73714.1 - 0.58 10.8 3.5 11 6.7 0.3 3.0 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain MIF4G PF02854.19 CDO73715.1 - 2.2e-23 83.0 1.1 5.1e-23 81.8 0.5 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 CDO73715.1 - 9.3e-18 64.3 0.0 1.5e-07 31.4 0.0 2.8 2 0 0 2 2 2 2 MA3 domain NOA36 PF06524.12 CDO73715.1 - 0.072 12.4 13.5 0.16 11.3 13.5 1.6 1 0 0 1 1 1 0 NOA36 protein Merozoite_SPAM PF07133.11 CDO73715.1 - 8.4 6.4 27.8 26 4.7 27.8 1.8 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2457 PF10446.9 CDO73715.1 - 8.9 5.3 35.9 2.3 7.3 17.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Methyltransf_31 PF13847.6 CDO73716.1 - 6e-12 45.6 0.0 3.9e-11 43.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO73716.1 - 4.6e-08 33.7 0.0 4.5e-06 27.3 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO73716.1 - 9.4e-06 26.2 0.0 0.012 16.2 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 CDO73716.1 - 1.6e-05 25.6 0.0 8.5e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO73716.1 - 0.00019 21.3 0.0 0.00037 20.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CDO73716.1 - 0.0017 18.3 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDO73716.1 - 0.046 13.0 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 CDO73716.1 - 0.093 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 CDO73716.1 - 0.12 11.6 0.0 3.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 CDO73716.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AAA_12 PF13087.6 CDO73717.1 - 6.7e-34 117.3 0.0 1.7e-33 115.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDO73717.1 - 3.2e-20 73.0 2.3 1.3e-13 51.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CDO73717.1 - 3.2e-12 46.6 0.0 1.1e-11 44.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDO73717.1 - 3.9e-08 33.8 0.1 1e-07 32.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CDO73717.1 - 3.9e-06 27.0 0.3 7.4e-06 26.1 0.0 1.6 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CDO73717.1 - 8.6e-06 26.2 0.0 2.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.14 CDO73717.1 - 1.4e-05 25.0 0.2 4.3e-05 23.4 0.0 1.9 2 1 0 2 2 2 1 Helicase ATPase PF06745.13 CDO73717.1 - 0.00069 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 KaiC PhoH PF02562.16 CDO73717.1 - 0.0015 18.1 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 CDO73717.1 - 0.0027 18.0 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDO73717.1 - 0.01 15.1 2.5 0.13 11.4 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 CDO73717.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 CDO73717.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 CDO73717.1 - 0.035 14.5 0.1 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CDO73717.1 - 0.044 13.5 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CDO73717.1 - 0.045 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ATPase_2 PF01637.18 CDO73717.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DEAD PF00270.29 CDO73717.1 - 0.2 11.4 0.8 0.69 9.7 0.8 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase Carn_acyltransf PF00755.20 CDO73718.1 - 2.1e-106 356.9 0.0 2.5e-106 356.6 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RMI1_N PF08585.12 CDO73719.1 - 8.5e-38 130.3 0.0 3.1e-37 128.5 0.0 1.8 2 0 0 2 2 2 1 RecQ mediated genome instability protein DnaJ PF00226.31 CDO73720.1 - 2.4e-18 66.0 1.9 6.3e-17 61.5 0.8 2.5 2 0 0 2 2 2 2 DnaJ domain CtaG_Cox11 PF04442.14 CDO73721.1 - 1.7e-60 203.4 0.0 2.1e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 TPR_19 PF14559.6 CDO73722.1 - 7.2e-13 48.8 5.3 3e-05 24.5 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDO73722.1 - 5.6e-09 36.5 0.3 0.00027 21.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDO73722.1 - 3.7e-08 32.9 1.1 0.58 10.4 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDO73722.1 - 2e-06 27.4 0.7 5.4 7.0 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDO73722.1 - 1.9e-05 24.7 0.1 0.24 11.9 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDO73722.1 - 0.00014 22.3 10.4 0.31 12.0 0.1 5.8 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDO73722.1 - 0.00022 21.2 0.1 2 8.9 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDO73722.1 - 0.0026 18.0 4.3 1.3 9.4 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDO73722.1 - 0.0047 17.0 0.4 0.2 11.7 0.1 2.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CDO73722.1 - 0.0053 17.0 0.6 29 5.0 0.0 3.8 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CDO73722.1 - 0.0056 15.9 0.1 0.53 9.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDO73722.1 - 0.012 16.2 5.9 7.5 7.4 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CDO73722.1 - 0.095 13.2 0.5 0.46 10.9 0.1 2.1 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_20 PF14561.6 CDO73722.1 - 0.14 12.5 2.6 12 6.3 0.2 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDO73722.1 - 0.15 12.2 0.8 3.3 8.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDO73722.1 - 0.34 11.7 2.1 10 7.1 0.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CDO73724.1 - 6.5e-36 123.1 1.7 1.1e-35 122.3 1.7 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 CDO73724.1 - 1.7e-10 40.7 0.0 3e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Mad3_BUB1_II PF08171.11 CDO73724.1 - 1.8e-06 28.0 0.0 6.2e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 CDO73724.1 - 4.7e-05 22.8 0.0 7.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 CDO73724.1 - 9.5e-05 22.5 0.1 0.00022 21.3 0.1 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein DGF-1_C PF11040.8 CDO73724.1 - 0.018 15.0 0.2 0.12 12.4 0.2 2.6 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Kdo PF06293.14 CDO73724.1 - 0.15 11.4 0.1 0.61 9.4 0.1 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cwf_Cwc_15 PF04889.12 CDO73724.1 - 2.3 7.9 26.5 0.07 12.8 2.7 2.6 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein LsmAD PF06741.13 CDO73725.1 - 8e-24 84.0 0.1 1.9e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 CDO73725.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain Phage_integrase PF00589.22 CDO73727.1 - 0.0057 16.5 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DIOX_N PF14226.6 CDO73730.1 - 1.5e-25 90.2 0.1 2.3e-25 89.6 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO73730.1 - 1.1e-16 61.1 0.0 2.4e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Type2_restr_D3 PF16902.5 CDO73730.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Snf7 PF03357.21 CDO73731.1 - 1.6e-43 148.3 11.5 2.8e-43 147.5 11.5 1.2 1 0 0 1 1 1 1 Snf7 DUF5344 PF17279.2 CDO73731.1 - 0.082 13.5 7.3 0.26 11.9 4.5 2.8 1 1 0 2 2 2 0 Family of unknown function (DUF5344) FlaC_arch PF05377.11 CDO73731.1 - 0.14 12.6 3.8 3.3 8.2 0.1 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 CDO73731.1 - 0.15 12.6 1.1 0.45 11.0 0.2 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NuA4 PF09340.10 CDO73731.1 - 0.22 11.4 2.3 1.1 9.2 0.3 2.9 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 Prominin PF05478.11 CDO73731.1 - 0.31 9.0 3.3 0.39 8.6 3.3 1.1 1 0 0 1 1 1 0 Prominin Uso1_p115_C PF04871.13 CDO73731.1 - 1.4 9.3 17.9 0.053 13.9 8.0 3.0 3 1 1 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-C4H2 PF10146.9 CDO73731.1 - 6.3 7.0 7.5 22 5.3 7.5 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein TMF_TATA_bd PF12325.8 CDO73731.1 - 6.7 7.0 13.4 1.4e+03 -0.5 13.1 2.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Aldedh PF00171.22 CDO73732.1 - 1.3e-144 482.1 0.0 2.4e-144 481.3 0.0 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_1 PF00561.20 CDO73732.1 - 1.4e-32 113.3 0.2 6.1e-31 108.0 0.1 2.5 2 1 0 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.20 CDO73732.1 - 0.0022 17.7 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 Putative esterase LuxC PF05893.14 CDO73732.1 - 0.0054 15.8 0.0 0.0087 15.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Nucleo_P87 PF07267.11 CDO73733.1 - 0.61 8.9 5.5 0.94 8.3 5.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Snf7 PF03357.21 CDO73734.1 - 8.3e-05 22.2 13.9 0.00012 21.7 13.3 1.6 1 1 0 1 1 1 1 Snf7 BLOC1S3 PF15753.5 CDO73734.1 - 0.067 13.3 5.4 0.02 15.0 2.7 1.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Phage_lysozyme2 PF18013.1 CDO73734.1 - 0.3 11.1 3.4 2.6 8.0 0.2 2.2 2 0 0 2 2 2 0 Phage tail lysozyme T3SS_basalb_I PF17001.5 CDO73734.1 - 3.5 8.3 12.4 6.5 7.4 3.9 3.0 2 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Cupin_8 PF13621.6 CDO73735.1 - 8.1e-55 186.3 0.0 1e-54 185.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CDO73735.1 - 3.1e-06 27.6 0.0 1.1e-05 25.8 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 CDO73735.1 - 0.019 14.6 0.1 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.12 CDO73735.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein ACT_7 PF13840.6 CDO73736.1 - 5.1e-14 51.8 0.1 4.4e-08 32.8 0.1 3.2 3 0 0 3 3 3 2 ACT domain SKN1 PF03935.15 CDO73737.1 - 1.8e-191 636.9 1.4 2.1e-191 636.7 1.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Pex14_N PF04695.13 CDO73738.1 - 1e-10 42.5 0.0 1e-10 42.5 0.0 4.5 3 2 2 5 5 5 2 Peroxisomal membrane anchor protein (Pex14p) conserved region TFR_dimer PF04253.15 CDO73739.1 - 1.6e-21 76.6 0.0 1.7e-20 73.3 0.0 2.5 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CDO73739.1 - 3.5e-18 66.0 0.0 6.8e-17 61.8 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CDO73739.1 - 2.7e-11 43.3 1.0 5.4e-11 42.4 0.3 1.8 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 CDO73739.1 - 0.00017 21.1 0.0 0.00084 18.9 0.0 1.9 2 0 0 2 2 2 1 Nicastrin FMN_dh PF01070.18 CDO73740.1 - 7e-101 337.7 0.0 1e-100 337.2 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CDO73740.1 - 1.8e-05 23.9 0.4 4.3e-05 22.7 0.2 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CDO73740.1 - 0.00021 20.6 0.2 0.00031 20.0 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CDO73740.1 - 0.0019 17.6 0.5 0.0029 17.1 0.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 CDO73740.1 - 0.0094 15.3 1.5 0.17 11.1 0.2 2.3 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 CDO73740.1 - 0.025 14.1 0.1 0.11 12.0 0.1 1.8 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 CDO73740.1 - 0.2 10.9 0.1 0.42 9.8 0.1 1.6 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase BicD PF09730.9 CDO73742.1 - 0.00028 19.5 3.5 0.00044 18.8 3.5 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D HALZ PF02183.18 CDO73742.1 - 0.0025 18.0 2.1 0.0054 16.9 2.1 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF2205 PF10224.9 CDO73742.1 - 0.061 13.3 0.3 0.061 13.3 0.3 2.3 2 1 1 3 3 3 0 Short coiled-coil protein Cep57_CLD_2 PF14197.6 CDO73742.1 - 4.1 7.6 8.8 22 5.2 8.3 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 stn_TNFRSF12A PF12191.8 CDO73743.1 - 0.00027 21.1 1.5 0.00029 21.1 0.2 1.7 2 0 0 2 2 2 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TMEM171 PF15471.6 CDO73743.1 - 0.3 10.0 0.0 0.3 10.0 0.0 2.4 1 1 1 2 2 2 0 Transmembrane protein family 171 GTP_cyclohydro2 PF00925.20 CDO73744.1 - 2.1e-62 209.5 0.0 3.3e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Vps5 PF09325.10 CDO73745.1 - 3.3e-15 56.3 0.8 4.3e-15 55.9 0.8 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CDO73745.1 - 3.1e-05 23.9 0.5 0.00011 22.2 0.0 2.1 2 0 0 2 2 2 1 PX domain tRNA-synt_1b PF00579.25 CDO73745.1 - 0.2 11.0 0.0 0.4 9.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Metal_resist PF13801.6 CDO73745.1 - 0.74 10.0 12.4 0.57 10.4 4.6 3.0 2 0 0 2 2 2 0 Heavy-metal resistance Iso_dh PF00180.20 CDO73746.1 - 3.1e-120 401.5 0.0 4.1e-120 401.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_M24 PF00557.24 CDO73746.1 - 3.1e-10 40.1 0.0 5.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 ALF PF03752.13 CDO73746.1 - 0.15 12.1 0.1 11 6.0 0.0 2.8 2 0 0 2 2 2 0 Short repeats of unknown function NOB1_Zn_bind PF08772.11 CDO73747.1 - 3.4e-29 100.8 0.4 5.5e-29 100.1 0.4 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 CDO73747.1 - 2.8e-28 98.2 0.0 4.7e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease Cwf_Cwc_15 PF04889.12 CDO73747.1 - 2.5 7.8 16.4 0.91 9.2 12.1 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein P21-Arc PF04062.14 CDO73748.1 - 2.9e-76 255.4 0.0 3.2e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Sld5 PF05916.11 CDO73750.1 - 3.7e-20 72.4 0.3 5.8e-20 71.8 0.3 1.3 1 0 0 1 1 1 1 GINS complex protein Haspin_kinase PF12330.8 CDO73751.1 - 4.9e-47 160.6 0.0 7.4e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Med8 PF10232.9 CDO73752.1 - 0.058 13.0 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 CE2_N PF17996.1 CDO73753.1 - 0.024 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Adeno_E3_CR2 PF02439.15 CDO73753.1 - 2.6 7.9 6.7 0.29 10.9 1.9 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 CDO73754.1 - 0.065 12.6 0.4 0.065 12.6 0.4 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PCRF PF03462.18 CDO73755.1 - 4.4e-29 101.7 1.2 6.9e-29 101.1 1.2 1.3 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 CDO73755.1 - 5.2e-20 71.5 0.0 2.2e-19 69.5 0.0 2.0 2 0 0 2 2 2 1 RF-1 domain PP2C PF00481.21 CDO73756.1 - 6.9e-17 61.9 0.0 1.3e-15 57.7 0.0 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDO73756.1 - 0.0091 15.6 0.0 2.1 7.9 0.0 2.6 2 1 0 2 2 2 2 Protein phosphatase 2C DUF2914 PF11141.8 CDO73756.1 - 0.33 10.7 0.1 0.33 10.7 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) UCH PF00443.29 CDO73757.1 - 1.3e-46 159.2 0.0 1.8e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDO73757.1 - 3.5e-18 66.3 0.0 6.7e-17 62.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CDO73757.1 - 0.019 14.5 0.7 0.086 12.3 0.7 2.1 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2175 PF09943.9 CDO73757.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2H2 PF00096.26 CDO73758.1 - 5e-06 26.7 24.9 0.004 17.5 1.3 4.8 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO73758.1 - 1.3e-05 25.4 6.4 0.0043 17.4 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDO73758.1 - 1.7e-05 25.2 16.6 0.017 15.9 0.1 4.8 4 1 0 4 4 4 2 C2H2-type zinc finger zf-Di19 PF05605.12 CDO73758.1 - 0.007 16.6 4.7 0.43 10.9 0.3 2.5 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CDO73758.1 - 0.013 15.8 4.8 1.3 9.4 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDO73758.1 - 0.019 15.3 1.9 7.4 7.1 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CDO73758.1 - 0.023 14.6 4.6 0.82 9.6 1.4 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 CDO73758.1 - 0.063 13.9 2.0 14 6.4 0.1 2.8 2 1 1 3 3 3 0 FOXP coiled-coil domain PX PF00787.24 CDO73758.1 - 0.092 12.7 0.5 0.21 11.6 0.3 1.8 2 0 0 2 2 2 0 PX domain Zn_ribbon_recom PF13408.6 CDO73758.1 - 0.13 12.8 4.9 0.17 12.4 3.1 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-H2C2_5 PF13909.6 CDO73758.1 - 0.15 11.9 7.1 0.51 10.2 0.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CDO73758.1 - 0.26 11.3 3.3 5.7 7.0 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDO73758.1 - 2.8 8.3 5.7 6.6 7.1 0.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) F-box PF00646.33 CDO73759.1 - 0.0004 20.2 0.3 0.0014 18.4 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CDO73759.1 - 0.0018 18.1 0.4 0.0034 17.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CDO73759.1 - 0.0046 16.8 0.1 0.0046 16.8 0.1 1.8 2 0 0 2 2 2 1 F-box Apo-CIII PF05778.12 CDO73760.1 - 0.1 12.2 0.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Velvet PF11754.8 CDO73761.1 - 3.8e-51 174.4 0.6 3.8e-51 174.4 0.6 2.7 1 1 1 2 2 2 1 Velvet factor PPR PF01535.20 CDO73762.1 - 5e-31 104.8 0.4 0.39 11.1 0.0 12.7 13 0 0 13 13 13 8 PPR repeat PPR_2 PF13041.6 CDO73762.1 - 5.2e-31 106.6 0.1 5.1e-06 26.6 0.0 9.4 6 2 4 10 10 10 7 PPR repeat family PPR_3 PF13812.6 CDO73762.1 - 2e-28 98.3 0.2 7.6e-07 29.1 0.0 6.8 5 2 2 7 7 7 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 CDO73762.1 - 4.2e-17 61.6 0.0 0.0099 15.6 0.0 8.8 11 0 0 11 11 11 4 PPR repeat PPR_long PF17177.4 CDO73762.1 - 3.6e-10 39.6 0.9 0.00085 18.7 0.0 4.4 2 1 3 5 5 5 3 Pentacotripeptide-repeat region of PRORP DUF3368 PF11848.8 CDO73762.1 - 0.0076 16.0 0.1 3.2 7.6 0.0 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF3368) DUF1298 PF06974.13 CDO73762.1 - 0.038 13.9 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) TPR_14 PF13428.6 CDO73762.1 - 0.048 14.5 5.2 31 5.7 0.1 6.2 6 2 2 8 8 8 0 Tetratricopeptide repeat rve_3 PF13683.6 CDO73762.1 - 0.11 12.3 0.0 2.8 7.8 0.2 2.9 3 0 0 3 3 3 0 Integrase core domain Acetyltransf_5 PF13444.6 CDO73763.1 - 4.6e-06 27.3 0.1 0.00096 19.8 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDO73763.1 - 4.4e-05 23.4 0.0 6.1e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDO73763.1 - 0.0018 18.7 0.0 0.0025 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO73763.1 - 0.0029 17.8 0.0 0.0035 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HMG_box PF00505.19 CDO73764.1 - 4.3e-13 49.5 17.8 8.8e-07 29.3 4.1 3.0 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO73764.1 - 1.1e-12 48.3 12.6 7.7e-06 26.4 5.3 2.6 2 0 0 2 2 2 2 HMG-box domain DUF4355 PF14265.6 CDO73764.1 - 0.012 15.9 9.3 0.052 13.8 3.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) ADSL_C PF10397.9 CDO73764.1 - 0.037 14.6 0.1 0.1 13.1 0.0 1.8 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus FAM178 PF14816.6 CDO73765.1 - 1.9 7.4 4.3 2.9 6.8 4.3 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 Macoilin PF09726.9 CDO73765.1 - 3.1 6.2 5.9 7 5.1 0.8 2.4 2 0 0 2 2 2 0 Macoilin family RP-C_C PF11800.8 CDO73766.1 - 0.83 9.7 5.4 0.31 11.1 0.1 2.1 1 1 1 2 2 2 0 Replication protein C C-terminal region Fer4 PF00037.27 CDO73767.1 - 6e-14 51.2 17.5 1.9e-08 33.8 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CDO73767.1 - 1.2e-12 48.2 9.2 2e-12 47.5 9.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CDO73767.1 - 4.2e-11 43.6 7.5 1.6e-05 25.8 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CDO73767.1 - 1.4e-09 37.9 5.8 0.00022 21.3 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CDO73767.1 - 7.1e-09 35.7 21.0 3.2e-06 27.1 12.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 CDO73767.1 - 1.4e-08 35.0 3.6 0.00015 22.1 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CDO73767.1 - 1.9e-08 34.3 9.5 3.4e-08 33.5 9.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CDO73767.1 - 4.7e-07 29.6 17.8 0.00043 20.2 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CDO73767.1 - 1.6e-06 27.8 12.1 0.003 17.6 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 CDO73767.1 - 7.2e-06 26.1 11.0 0.00035 20.9 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CDO73767.1 - 0.00011 22.7 10.4 0.012 16.1 11.8 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 CDO73767.1 - 0.00046 20.7 9.7 0.1 13.2 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 CDO73767.1 - 0.0059 16.8 5.2 0.56 10.5 0.3 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 CDO73767.1 - 0.055 13.7 8.9 12 6.2 8.9 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 CDO73767.1 - 0.25 12.4 16.3 0.38 11.8 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 CDO73767.1 - 0.53 11.2 11.9 1.7 9.5 1.4 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain ETF_QO PF05187.13 CDO73767.1 - 0.71 10.0 6.3 3.6 7.8 0.8 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 CDO73767.1 - 0.84 9.7 5.6 0.53 10.3 0.5 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins SAVED PF18145.1 CDO73768.1 - 0.059 13.2 0.1 0.093 12.5 0.1 1.2 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain SET PF00856.28 CDO73769.1 - 3.7e-10 40.4 0.0 2.7e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.6 CDO73769.1 - 0.0013 18.4 0.4 0.0033 17.1 0.4 1.8 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 CDO73769.1 - 0.0067 16.5 18.3 0.027 14.6 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDO73769.1 - 0.14 12.3 7.2 0.085 13.0 3.5 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDO73769.1 - 0.25 11.3 0.1 0.25 11.3 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DNA_mis_repair PF01119.19 CDO73770.1 - 2.9e-12 46.3 0.1 1.2e-05 25.0 0.0 2.2 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 CDO73770.1 - 3.4e-07 30.1 0.0 2.9e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_pol_A_exo1 PF01612.20 CDO73771.1 - 1.5e-07 31.3 0.0 5.9e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease SBDS PF01172.18 CDO73772.1 - 5.5e-19 68.0 0.0 7.7e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein GATase_7 PF13537.6 CDO73772.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain DAO PF01266.24 CDO73773.1 - 9.7e-42 143.8 0.8 4e-41 141.8 0.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDO73773.1 - 9.1e-05 22.9 0.0 0.0078 16.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO73773.1 - 0.00036 20.7 0.1 0.00086 19.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDO73773.1 - 0.00046 19.5 0.0 0.02 14.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO73773.1 - 0.0044 17.0 0.1 0.1 12.6 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CDO73773.1 - 0.21 10.6 0.2 1.1 8.3 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Isochorismatase PF00857.20 CDO73774.1 - 1e-07 32.3 0.0 2.8e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family AFG1_ATPase PF03969.16 CDO73775.1 - 1.4e-100 336.7 0.0 1.1e-96 324.0 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 CDO73775.1 - 3.2e-05 24.4 0.0 0.044 14.2 0.0 2.8 1 1 2 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CDO73775.1 - 0.00019 21.7 0.0 0.0029 17.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CDO73775.1 - 0.00083 19.8 0.0 0.0056 17.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 CDO73775.1 - 0.013 15.3 0.1 0.051 13.4 0.1 1.9 1 1 0 1 1 1 0 Bacterial dnaA protein TniB PF05621.11 CDO73775.1 - 0.016 14.6 0.0 0.062 12.7 0.0 1.9 1 1 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 CDO73775.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CDO73775.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GMC_oxred_N PF00732.19 CDO73776.1 - 1.3e-31 110.0 0.0 3.7e-21 75.8 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO73776.1 - 3.6e-05 24.3 0.0 6.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CDO73776.1 - 0.00013 21.1 0.2 0.00023 20.4 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CDO73776.1 - 0.00051 20.2 1.3 0.0007 19.8 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDO73776.1 - 0.00061 19.5 0.3 0.0025 17.5 0.1 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CDO73776.1 - 0.00082 18.5 0.1 0.0012 18.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CDO73776.1 - 0.0022 17.3 0.3 0.018 14.3 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO73776.1 - 0.005 16.1 0.1 0.011 15.0 0.1 1.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 CDO73776.1 - 0.046 12.4 0.1 0.099 11.3 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 CDO73776.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RNF220 PF15926.5 CDO73777.1 - 1.6e-20 73.8 3.1 1.6e-20 73.8 3.1 2.2 2 1 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 CDO73777.1 - 6.9e-09 35.4 14.9 6.9e-09 35.4 14.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDO73777.1 - 7.1e-07 29.0 21.4 9.5e-05 22.2 11.8 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO73777.1 - 1.3e-05 25.0 21.5 8.3e-05 22.5 12.8 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDO73777.1 - 0.00019 21.2 14.6 0.00019 21.2 14.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO73777.1 - 0.00068 19.9 25.9 0.00084 19.6 16.3 3.3 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CDO73777.1 - 0.00083 19.3 8.4 0.00083 19.3 8.4 4.2 4 0 0 4 4 4 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDO73777.1 - 0.014 15.3 20.5 0.69 9.8 12.3 3.7 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 CDO73777.1 - 0.027 14.7 6.7 3.1 8.2 0.5 4.0 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding ALIX_LYPXL_bnd PF13949.6 CDO73777.1 - 0.045 13.0 2.0 0.093 12.0 2.0 1.5 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV zf_UBZ PF18439.1 CDO73777.1 - 0.072 12.7 3.0 5.9 6.6 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger ThiD2 PF17792.1 CDO73777.1 - 0.13 12.8 2.4 0.46 11.0 0.1 2.5 2 0 0 2 2 2 0 ThiD2 family PRP21_like_P PF12230.8 CDO73777.1 - 0.24 11.2 3.3 1.2 8.9 0.3 2.6 2 1 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-ribbon_3 PF13248.6 CDO73777.1 - 0.34 10.4 5.4 6.8 6.2 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2HC_2 PF13913.6 CDO73777.1 - 1.3 9.0 8.4 22 5.1 0.5 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-RING_6 PF14835.6 CDO73777.1 - 1.6 8.7 17.2 0.054 13.4 9.1 2.7 4 0 0 4 4 3 0 zf-RING of BARD1-type protein Zn-C2H2_12 PF18112.1 CDO73777.1 - 2.2 8.8 15.4 11 6.6 0.2 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-Nse PF11789.8 CDO73777.1 - 2.9 7.8 15.1 0.37 10.6 6.8 2.7 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit DUF4451 PF14616.6 CDO73777.1 - 6.5 7.0 8.7 33 4.7 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4451) UBZ_FAAP20 PF15750.5 CDO73777.1 - 7.1 6.7 5.9 8.7 6.4 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger JAB PF01398.21 CDO73778.1 - 5.7e-23 81.1 0.1 9.5e-23 80.4 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CDO73778.1 - 5.7e-18 65.4 0.0 9.8e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UreF PF01730.16 CDO73779.1 - 2.8e-22 79.7 1.9 1.8e-14 54.4 0.1 2.2 2 0 0 2 2 2 2 UreF Vac14_Fig4_bd PF11916.8 CDO73780.1 - 2e-79 265.4 8.0 3.6e-79 264.6 8.0 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CDO73780.1 - 8.8e-41 138.4 0.0 4.7e-37 126.5 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CDO73780.1 - 7.8e-11 41.3 1.9 0.0021 18.2 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 CDO73780.1 - 6.2e-09 36.2 0.7 0.22 12.0 0.0 6.4 4 2 2 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 CDO73780.1 - 8.7e-06 26.0 0.6 4.3 7.8 0.1 5.0 4 1 1 5 5 5 2 HEAT repeats Cnd1 PF12717.7 CDO73780.1 - 2.9e-05 24.2 2.0 0.31 11.0 0.0 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 CDO73780.1 - 0.0022 18.1 0.7 1.1 9.3 0.0 3.4 3 0 0 3 3 3 1 Parkin co-regulated protein TAF6_C PF07571.13 CDO73780.1 - 0.015 15.6 0.2 0.42 11.0 0.0 3.1 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain Y_phosphatase3 PF13350.6 CDO73781.1 - 3.5e-34 118.8 0.0 5.5e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family MCM PF00493.23 CDO73782.1 - 2.2e-104 347.4 0.3 3.9e-104 346.6 0.3 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CDO73782.1 - 1.2e-38 131.8 0.0 2.3e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 CDO73782.1 - 6.9e-30 103.5 2.0 1.4e-29 102.5 2.0 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 CDO73782.1 - 8.1e-26 90.6 0.2 2.2e-25 89.2 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 CDO73782.1 - 7.7e-25 87.1 3.8 8.5e-25 87.0 2.0 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CDO73782.1 - 4.4e-07 29.5 0.0 4.4e-06 26.2 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDO73782.1 - 0.0018 18.2 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CDO73782.1 - 0.0037 17.0 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 CDO73782.1 - 0.031 14.3 0.0 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FH2 PF02181.23 CDO73783.1 - 1.4e-67 228.4 0.0 1.4e-67 228.4 0.0 3.4 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CDO73783.1 - 1.5e-26 93.1 0.1 4.9e-21 75.1 0.0 2.9 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CDO73783.1 - 4.6e-23 81.8 1.1 1.1e-22 80.6 1.1 1.6 1 0 0 1 1 1 1 Diaphanous FH3 Domain Fez1 PF06818.15 CDO73783.1 - 0.0021 18.5 13.4 0.05 14.1 3.3 2.8 1 1 1 2 2 2 2 Fez1 DUF4407 PF14362.6 CDO73783.1 - 0.078 12.3 13.7 0.15 11.4 2.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CDO73783.1 - 0.56 10.9 18.6 8.3 7.1 0.1 5.5 4 0 0 4 4 4 0 SlyX SOGA PF11365.8 CDO73783.1 - 0.85 10.8 13.6 2.6 9.2 1.2 4.4 4 0 0 4 4 3 0 Protein SOGA CENP-F_leu_zip PF10473.9 CDO73783.1 - 3.7 7.6 19.0 0.62 10.1 2.0 4.1 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 CDO73783.1 - 5.2 6.7 16.4 3.8 7.1 0.2 3.8 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Seryl_tRNA_N PF02403.22 CDO73783.1 - 6 7.1 21.8 13 6.0 1.4 4.3 3 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain IFT57 PF10498.9 CDO73783.1 - 8.8 5.2 11.6 0.64 8.9 1.3 2.8 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 IU_nuc_hydro PF01156.19 CDO73784.1 - 1.6e-36 126.5 0.0 1.7e-36 126.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RRN3 PF05327.11 CDO73785.1 - 1.1e-204 681.1 0.0 1.1e-204 681.1 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF5414 PF17435.2 CDO73785.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5414) GCIP PF13324.6 CDO73785.1 - 1.1 8.9 11.5 0.54 9.8 2.7 2.4 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting F-box PF00646.33 CDO73786.1 - 0.00013 21.8 0.1 0.00031 20.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO73786.1 - 0.00049 19.9 0.1 0.00049 19.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like PQQ_2 PF13360.6 CDO73786.1 - 0.057 13.0 0.1 5.9 6.4 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain PQQ PF01011.21 CDO73786.1 - 0.064 13.2 0.0 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat DUF2227 PF09988.9 CDO73787.1 - 0.093 12.6 0.1 0.093 12.6 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) Abhydrolase_1 PF00561.20 CDO73788.1 - 8.9e-24 84.5 0.0 2.2e-23 83.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO73788.1 - 6.3e-17 62.9 0.1 1.8e-16 61.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO73788.1 - 1.2e-08 34.6 0.0 0.00036 19.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 CDO73788.1 - 9.1e-07 27.9 0.0 3.4e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Ndr family DLH PF01738.18 CDO73788.1 - 0.063 12.8 0.0 6.1 6.3 0.0 2.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Btz PF09405.10 CDO73789.1 - 8.2e-11 42.3 8.0 8.2e-11 42.3 8.0 3.5 3 1 1 4 4 4 1 CASC3/Barentsz eIF4AIII binding DNA_pol_phi PF04931.13 CDO73789.1 - 1.8 6.5 5.0 2.7 6.0 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 CDO73790.1 - 6.5e-19 68.1 49.3 1.2e-11 44.1 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CDO73790.1 - 1.4e-07 30.4 19.2 1.1e-05 24.2 7.3 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein DLIC PF05783.11 CDO73791.1 - 1.4e-42 146.1 2.1 2e-35 122.5 0.0 4.4 3 2 0 4 4 4 2 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 CDO73791.1 - 0.0012 19.2 0.0 0.0039 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 CDO73791.1 - 0.0052 17.0 0.0 0.018 15.3 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CDO73791.1 - 0.011 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CDO73791.1 - 0.032 13.8 0.0 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CDO73791.1 - 0.049 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CDO73791.1 - 0.099 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CDO73791.1 - 0.11 12.7 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CDO73791.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CDO73791.1 - 0.13 12.0 0.0 4.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CDO73791.1 - 0.15 12.0 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Egg_lysin PF01303.17 CDO73791.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) FtsK_SpoIIIE PF01580.18 CDO73791.1 - 0.21 10.9 0.0 0.55 9.5 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family TIP41 PF04176.13 CDO73792.1 - 2.2e-63 212.8 0.0 2.9e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family zf-U11-48K PF05253.12 CDO73792.1 - 0.2 11.6 1.3 0.4 10.6 0.2 2.2 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger RRS1 PF04939.12 CDO73793.1 - 7.6e-61 204.7 7.2 1.3e-60 203.9 7.2 1.4 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) TFIIB PF00382.19 CDO73794.1 - 3.3e-34 116.7 0.0 1.1e-19 70.2 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CDO73794.1 - 3.6e-13 48.8 1.5 6.3e-13 48.0 1.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Guanylin PF02058.15 CDO73794.1 - 0.00078 19.9 2.9 0.21 12.1 0.1 3.1 1 1 2 3 3 3 2 Guanylin precursor HTH_5 PF01022.20 CDO73794.1 - 0.0023 17.8 0.6 3.3 7.6 0.1 3.4 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family RB_B PF01857.20 CDO73794.1 - 0.0077 16.3 0.2 0.015 15.4 0.0 1.6 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 CDO73794.1 - 0.01 15.9 0.0 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 CDO73794.1 - 0.041 13.4 0.0 0.19 11.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-70, region 4 Cyclin_N PF00134.23 CDO73794.1 - 0.05 13.4 0.1 0.091 12.5 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain TMIE PF16038.5 CDO73794.1 - 0.17 11.7 0.6 0.53 10.2 0.1 2.0 2 0 0 2 2 2 0 TMIE protein Hep_59 PF07052.11 CDO73795.1 - 6.3e-29 100.8 5.9 6.3e-29 100.8 5.9 2.3 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 PAPS_reduct PF01507.19 CDO73796.1 - 1.4e-41 142.4 0.0 2e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family dsrm PF00035.26 CDO73797.1 - 5.8e-08 33.3 0.0 1e-07 32.6 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 CDO73797.1 - 0.0005 20.2 0.0 0.00086 19.5 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CDO73797.1 - 0.027 15.1 0.0 0.043 14.4 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease III domain Coiled-coil_56 PF09813.9 CDO73798.1 - 9.5e-07 28.8 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 COX7a PF02238.15 CDO73799.1 - 1.9e-19 69.8 0.9 2.2e-19 69.6 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII YEATS PF03366.16 CDO73800.1 - 5.8e-30 103.1 0.0 1e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 YEATS family eIF-4B PF06273.11 CDO73800.1 - 0.038 13.1 3.4 0.056 12.5 3.4 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B THOC7 PF05615.13 CDO73800.1 - 0.066 13.5 2.5 0.11 12.8 2.5 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 M16C_assoc PF08367.11 CDO73800.1 - 0.077 12.1 6.2 0.1 11.7 6.2 1.1 1 0 0 1 1 1 0 Peptidase M16C associated CCDC-167 PF15188.6 CDO73800.1 - 0.22 11.9 3.6 0.43 10.9 3.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.20 CDO73800.1 - 0.81 9.7 8.2 1.1 9.2 8.2 1.2 1 0 0 1 1 1 0 Prefoldin subunit PI3_PI4_kinase PF00454.27 CDO73801.1 - 8.4e-55 186.3 0.0 2e-54 185.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CDO73801.1 - 3.8e-33 115.1 0.0 7.3e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.13 CDO73801.1 - 1.7e-29 101.7 0.0 1.3e-28 98.9 0.0 2.7 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 CDO73801.1 - 2.2e-11 43.3 0.1 6.5e-11 41.9 0.1 1.8 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.7 CDO73801.1 - 0.00023 21.2 0.0 4.3 7.4 0.0 4.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDO73801.1 - 0.00038 20.9 0.4 0.29 11.7 0.4 4.8 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 CDO73801.1 - 0.0013 18.8 0.9 37 5.0 0.0 5.9 5 0 0 5 5 5 0 HEAT repeat DUF3385 PF11865.8 CDO73801.1 - 0.019 14.9 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) TSKS PF15358.6 CDO73801.1 - 0.023 13.1 3.1 0.01 14.3 0.6 1.5 2 0 0 2 2 2 0 Testis-specific serine kinase substrate DHHA2 PF02833.14 CDO73801.1 - 0.081 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 DHHA2 domain Radial_spoke PF04712.12 CDO73801.1 - 0.2 10.6 0.5 3.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein Nop14 PF04147.12 CDO73803.1 - 0 1027.6 22.9 0 1027.2 22.9 1.1 1 0 0 1 1 1 1 Nop14-like family TetR_C_6 PF13977.6 CDO73803.1 - 0.027 14.7 0.1 0.1 12.8 0.1 2.0 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal SMC_Nse1 PF07574.13 CDO73803.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.6 3 0 0 3 3 3 0 Nse1 non-SMC component of SMC5-6 complex CNH PF00780.22 CDO73804.1 - 6.3e-05 22.7 0.0 0.011 15.3 0.0 2.6 3 0 0 3 3 3 2 CNH domain TRP PF06011.12 CDO73805.1 - 3.1e-30 105.3 16.6 7.2e-30 104.1 16.6 1.5 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.15 CDO73805.1 - 0.028 14.8 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 ML domain ING PF12998.7 CDO73806.1 - 4.4e-13 49.7 0.9 1.1e-12 48.4 0.7 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CDO73806.1 - 2.4e-05 24.1 2.8 5.1e-05 23.1 2.8 1.5 1 0 0 1 1 1 1 PHD-finger Phage_min_cap2 PF06152.11 CDO73806.1 - 0.22 10.4 1.6 0.57 9.0 1.6 1.6 1 1 0 1 1 1 0 Phage minor capsid protein 2 PHD20L1_u1 PF16660.5 CDO73806.1 - 3.7 8.4 6.2 0.78 10.5 0.9 2.3 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 GATA PF00320.27 CDO73807.1 - 3.8e-08 32.8 5.3 6.6e-08 32.0 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger CUE PF02845.16 CDO73809.1 - 1e-05 25.1 0.0 2.7e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 CUE domain Rhomboid PF01694.22 CDO73809.1 - 0.00022 21.3 4.7 0.00041 20.4 4.7 1.5 1 1 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 CDO73809.1 - 0.00063 20.3 0.6 0.001 19.6 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) TPPII_N PF12583.8 CDO73809.1 - 1.1 9.8 4.3 1.9 9.1 4.3 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal eIF-3_zeta PF05091.12 CDO73810.1 - 2.1e-209 696.8 0.0 2.5e-209 696.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.22 CDO73811.1 - 2.3e-19 69.0 0.0 3.9e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDO73811.1 - 1.9e-07 31.1 0.0 4.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 CDO73811.1 - 0.00019 21.0 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDO73811.1 - 0.042 13.8 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MMU163 PF17119.5 CDO73811.1 - 0.083 12.0 1.3 0.16 11.1 1.3 1.4 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Beta_helix PF13229.6 CDO73812.1 - 4.7e-12 46.0 24.9 4.8e-09 36.3 14.7 2.9 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 CDO73812.1 - 0.00026 20.4 12.5 0.0061 15.8 12.5 2.4 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Disaggr_assoc PF08480.10 CDO73812.1 - 0.00033 20.6 10.5 0.022 14.6 4.5 3.2 2 1 0 2 2 2 1 Disaggregatase related VSP PF03302.13 CDO73812.1 - 8.5 5.1 9.8 0.08 11.8 1.0 2.0 3 0 0 3 3 3 0 Giardia variant-specific surface protein PAP_central PF04928.17 CDO73813.1 - 3.4e-178 589.6 0.0 1.2e-112 374.9 0.0 3.2 2 1 1 3 3 3 3 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CDO73813.1 - 1.5e-109 363.2 0.2 4.7e-57 192.3 0.0 2.3 2 0 0 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CDO73813.1 - 9.6e-25 86.7 0.0 7.4e-12 45.4 0.0 2.6 2 0 0 2 2 2 2 Nucleotidyltransferase domain Polbeta PF18765.1 CDO73813.1 - 3.9e-05 23.7 0.0 0.54 10.4 0.0 2.6 2 0 0 2 2 2 2 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 CDO73813.1 - 0.00024 21.3 0.0 1.5 9.1 0.0 3.7 3 0 0 3 3 3 2 DNA polymerase beta palm Peptidase_S49 PF01343.18 CDO73813.1 - 0.013 15.4 0.0 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Peptidase family S49 FtsK_gamma PF09397.10 CDO73813.1 - 0.025 14.4 0.5 2.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Ftsk gamma domain Nrap_D2 PF17403.2 CDO73813.1 - 0.037 13.8 0.2 0.071 12.9 0.2 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Tape_meas_lam_C PF09718.10 CDO73813.1 - 0.2 11.8 0.1 15 5.8 0.1 2.5 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) GatB_N PF02934.15 CDO73814.1 - 9.4e-94 313.8 0.0 1.7e-91 306.4 0.0 2.2 1 1 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CDO73814.1 - 1.9e-27 96.0 0.0 1.1e-16 61.0 0.0 2.2 2 0 0 2 2 2 2 GatB domain Thioredoxin_4 PF13462.6 CDO73815.1 - 1.1e-08 35.5 0.0 3.3e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin PCI PF01399.27 CDO73816.1 - 3.6e-14 53.2 0.0 8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain VWA PF00092.28 CDO73817.1 - 0.00036 20.8 0.0 0.0014 18.9 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CDO73817.1 - 0.12 13.1 0.0 0.46 11.2 0.0 2.1 1 1 0 1 1 1 0 von Willebrand factor type A domain GCP_N_terminal PF17681.1 CDO73818.1 - 8.8e-35 120.8 0.0 1.7e-34 119.9 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CDO73818.1 - 1.2e-23 84.1 0.5 2e-21 76.7 0.1 2.6 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal Mgm101p PF06420.12 CDO73819.1 - 3.3e-86 287.1 0.0 4.3e-86 286.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Peptidase_S10 PF00450.22 CDO73823.1 - 1.3e-102 344.4 0.0 1.6e-102 344.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PepSY_TM PF03929.16 CDO73823.1 - 0.13 11.9 0.2 0.23 11.1 0.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM region MoCF_biosynth PF00994.24 CDO73824.1 - 7.7e-51 171.5 0.0 4.2e-26 91.3 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 CDO73824.1 - 5.3e-32 110.7 0.0 8.5e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 CDO73824.1 - 2.5e-13 50.0 0.1 6.7e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) TrmO_C PF18389.1 CDO73824.1 - 0.013 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 TrmO C-terminal domain GDPD PF03009.17 CDO73825.1 - 1.8e-28 100.0 0.0 2.7e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 CDO73825.1 - 0.00013 22.3 1.1 0.00029 21.2 0.6 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 CDO73826.1 - 7.6e-29 101.2 0.0 1.6e-28 100.1 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 CDO73826.1 - 3e-06 27.5 0.7 7.7e-06 26.2 0.2 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Glyco_hydro_20 PF00728.22 CDO73826.1 - 0.00052 19.5 0.2 0.00072 19.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain DUF2387 PF09526.10 CDO73826.1 - 0.17 12.1 0.2 0.42 10.8 0.2 1.7 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) ATF7IP_BD PF16788.5 CDO73827.1 - 3.3 7.8 9.7 0.25 11.4 4.2 1.9 1 1 1 2 2 2 0 ATF-interacting protein binding domain Acyltransferase PF01553.21 CDO73829.1 - 7.5e-34 116.2 0.0 1.1e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Silic_transp PF03842.13 CDO73829.1 - 0.084 11.2 0.0 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Silicon transporter Amidohydro_1 PF01979.20 CDO73830.1 - 8.4e-30 104.2 0.4 1.8e-22 80.1 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CDO73830.1 - 1.7e-17 64.1 0.2 6e-11 42.5 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family TPR_2 PF07719.17 CDO73832.1 - 1.2e-06 28.2 0.6 0.5 10.6 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDO73832.1 - 2.1e-06 27.3 0.1 0.34 10.8 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDO73832.1 - 0.0005 20.1 0.1 2.5 8.5 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.31 CDO73832.1 - 0.0024 17.7 0.6 0.0081 16.1 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain DnaJ PF00226.31 CDO73832.1 - 0.0051 16.9 0.1 0.015 15.5 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain TPR_12 PF13424.6 CDO73832.1 - 0.017 15.4 0.1 0.017 15.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDO73832.1 - 0.082 13.0 0.1 3.2 8.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_1g PF09334.11 CDO73833.1 - 1.4e-72 244.6 0.1 9.4e-53 179.4 0.0 3.0 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CDO73833.1 - 2.7e-15 55.7 0.1 4.4e-10 38.5 0.0 2.9 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CDO73833.1 - 1.6e-11 44.1 0.0 6.3e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 CDO73833.1 - 0.0064 16.5 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Aldo_ket_red PF00248.21 CDO73835.1 - 2.2e-64 217.5 0.0 2.7e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SUI1 PF01253.22 CDO73836.1 - 2.8e-22 79.0 1.1 5.4e-22 78.1 1.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.6 CDO73836.1 - 0.057 13.4 1.6 0.13 12.3 1.6 1.6 1 0 0 1 1 1 0 Transposon-encoded protein TnpV DAHP_synth_2 PF01474.16 CDO73838.1 - 6.4e-200 664.2 0.0 7.2e-200 664.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family RRM_1 PF00076.22 CDO73839.1 - 0.00041 20.1 0.3 13 5.7 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMK-1 PF04802.15 CDO73840.1 - 4.8e-79 264.7 1.5 7.9e-79 263.9 0.9 1.7 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 RICTOR_M PF14666.6 CDO73840.1 - 0.0027 17.5 0.9 0.017 14.9 0.2 2.5 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain EVE PF01878.18 CDO73841.1 - 2.6e-46 157.3 0.3 4.6e-46 156.4 0.3 1.4 1 0 0 1 1 1 1 EVE domain Abhydrolase_2 PF02230.16 CDO73842.1 - 7.4e-44 150.1 0.0 1.3e-41 142.8 0.0 2.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CDO73842.1 - 7.9e-06 25.3 0.1 0.0044 16.3 0.1 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO73842.1 - 7.6e-05 23.4 0.1 0.00011 22.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 CDO73842.1 - 0.0028 17.3 0.0 0.0058 16.3 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF4939 PF16297.5 CDO73843.1 - 2.7e-09 36.9 0.0 4.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 CDO73843.1 - 6.8e-05 23.1 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DPBB_1 PF03330.18 CDO73844.1 - 9.3e-09 35.5 0.1 1.6e-08 34.7 0.1 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CDO73844.1 - 0.011 15.6 0.3 0.015 15.2 0.3 1.3 1 0 0 1 1 1 0 Barwin family Integrase_H2C2 PF17921.1 CDO73846.1 - 1.3e-16 60.5 0.0 3.1e-16 59.2 0.0 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CDO73846.1 - 3.4e-13 49.8 0.0 8.1e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO73846.1 - 2.6e-08 33.6 0.0 4.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CDO73846.1 - 3.1e-05 24.1 0.0 8.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger rve_3 PF13683.6 CDO73846.1 - 0.071 12.9 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain RVT_2 PF07727.14 CDO73847.1 - 2.8e-18 66.5 0.0 1.1e-14 54.6 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3799 PF12684.7 CDO73847.1 - 0.069 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) Glyco_hydro_cc PF11790.8 CDO73849.1 - 3.6e-54 183.9 0.0 4.5e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.8 CDO73850.1 - 1.8e-44 152.1 0.0 2.1e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Peptidase_S7 PF00949.21 CDO73851.1 - 0.1 12.4 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease 7tm_6 PF02949.20 CDO73851.1 - 0.18 10.8 5.0 0.041 13.0 1.1 1.8 2 0 0 2 2 2 0 7tm Odorant receptor DUF3712 PF12505.8 CDO73852.1 - 2.9e-115 379.7 55.1 1.9e-27 96.0 0.2 10.6 11 0 0 11 11 11 7 Protein of unknown function (DUF3712) LEA_2 PF03168.13 CDO73852.1 - 2.6e-11 44.0 19.7 0.16 12.5 0.2 9.1 9 0 0 9 9 9 5 Late embryogenesis abundant protein Ribo_biogen_C PF04034.13 CDO73853.1 - 6.8e-55 184.2 0.0 8.5e-55 183.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CDO73853.1 - 9.4e-12 44.6 0.2 1.5e-11 43.9 0.2 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI MRP-L27 PF09809.9 CDO73854.1 - 3.8e-10 39.6 0.3 5.2e-10 39.2 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SnoaL_2 PF12680.7 CDO73855.1 - 0.03 15.0 0.0 0.052 14.2 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain Glyco_hydro_79C PF16862.5 CDO73856.1 - 2.7e-22 79.6 0.5 1e-21 77.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain DDE_3 PF13358.6 CDO73857.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease FMO-like PF00743.19 CDO73859.1 - 3.6e-24 85.1 0.0 1.3e-06 27.1 0.0 4.5 4 1 0 4 4 4 4 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CDO73859.1 - 1.9e-22 79.9 1.9 1.7e-07 30.8 1.4 5.1 3 2 1 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDO73859.1 - 3e-12 46.4 3.8 0.65 9.2 0.0 6.2 6 0 0 6 6 6 4 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDO73859.1 - 9.8e-11 41.4 2.4 0.0035 16.5 0.0 5.6 6 0 0 6 6 6 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CDO73859.1 - 5.8e-10 38.8 9.1 0.054 12.8 1.4 4.2 4 0 0 4 4 4 4 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 CDO73859.1 - 1.9e-09 37.6 18.5 4.1e-07 30.1 0.7 4.2 4 0 0 4 4 4 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CDO73859.1 - 2.6e-09 37.5 7.6 0.17 12.5 0.0 4.6 4 0 0 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CDO73859.1 - 1.9e-08 34.0 0.5 0.12 11.6 0.1 4.2 4 0 0 4 4 4 2 Flavin containing amine oxidoreductase DAO PF01266.24 CDO73859.1 - 3e-08 33.7 16.1 0.00022 21.0 3.5 4.4 5 1 0 5 5 5 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CDO73859.1 - 2.5e-07 31.1 0.7 0.14 12.6 0.0 4.1 4 0 0 4 4 4 2 Putative NAD(P)-binding NAD_binding_9 PF13454.6 CDO73859.1 - 1.1e-06 28.8 15.9 0.0024 17.9 0.0 6.8 7 2 1 8 8 8 2 FAD-NAD(P)-binding 3HCDH_N PF02737.18 CDO73859.1 - 2.3e-06 27.6 4.8 0.012 15.5 0.0 2.7 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 CDO73859.1 - 7.5e-06 25.3 12.7 0.011 14.8 0.0 4.2 4 0 0 4 4 4 2 FAD binding domain Shikimate_DH PF01488.20 CDO73859.1 - 7.8e-06 26.0 0.6 1.9 8.5 0.0 4.3 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 CDO73859.1 - 0.00086 19.5 0.6 1.6 8.9 0.0 2.8 3 0 0 3 3 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 CDO73859.1 - 0.0035 16.5 14.6 0.33 10.0 0.3 4.8 5 0 0 5 5 5 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CDO73859.1 - 0.035 13.2 0.7 4.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 CDO73859.1 - 0.055 12.2 18.0 0.32 9.7 2.2 4.2 4 0 0 4 4 4 0 HI0933-like protein MTS_N PF08468.11 CDO73859.1 - 0.071 13.2 4.1 7.4 6.6 0.1 3.9 4 0 0 4 4 4 0 Methyltransferase small domain N-terminal F420_oxidored PF03807.17 CDO73859.1 - 0.11 13.1 1.6 11 6.7 0.0 3.2 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent FAD_oxidored PF12831.7 CDO73859.1 - 0.61 9.4 22.4 0.024 14.0 1.8 3.8 4 0 0 4 4 4 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 CDO73859.1 - 0.7 9.4 3.5 11 5.5 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 CDO73859.1 - 4.5 6.4 8.3 9 5.4 0.0 3.4 4 0 0 4 4 4 0 FAD binding domain ArfGap PF01412.18 CDO73860.1 - 0.004 17.2 1.1 0.015 15.4 1.1 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Fer4_24 PF18109.1 CDO73860.1 - 0.088 13.1 1.2 0.17 12.2 1.2 1.5 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain DUF5368 PF17336.2 CDO73861.1 - 0.092 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5368) EOS1 PF12326.8 CDO73862.1 - 8.6e-35 120.2 1.0 1.9e-34 119.1 1.0 1.5 1 0 0 1 1 1 1 N-glycosylation protein Pneumo_att_G PF05539.11 CDO73862.1 - 7 6.1 7.4 13 5.2 7.4 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MFS_1 PF07690.16 CDO73863.1 - 1.9e-25 89.6 31.9 1.9e-25 89.6 31.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MNSV_P7B PF06692.11 CDO73863.1 - 0.33 11.0 1.5 0.97 9.5 0.1 2.5 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein DUF2070 PF09843.9 CDO73863.1 - 0.87 7.8 13.7 1.5 7.1 1.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) SE PF08491.10 CDO73864.1 - 8.9e-96 320.2 0.0 1.2e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 CDO73864.1 - 3.6e-10 40.0 0.1 0.00037 20.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDO73864.1 - 1.4e-06 27.8 0.1 1.9e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 CDO73864.1 - 0.00016 20.7 0.3 0.2 10.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 CDO73864.1 - 0.0017 18.5 0.2 0.0038 17.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDO73864.1 - 0.0054 15.9 1.6 0.63 9.1 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 CDO73864.1 - 0.017 14.2 0.1 0.033 13.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 CDO73864.1 - 0.024 14.6 0.3 0.067 13.2 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CDO73864.1 - 0.04 14.2 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 CDO73864.1 - 0.063 12.5 0.8 0.18 11.0 0.8 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO73864.1 - 0.099 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 CDO73864.1 - 1.9 7.5 4.2 23 3.9 4.2 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A Diphthamide_syn PF01866.17 CDO73865.1 - 1.1e-100 337.0 0.0 1.4e-100 336.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPR_1 PF00515.28 CDO73866.1 - 4.1e-45 149.8 10.4 9.8e-06 25.2 0.0 10.6 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 CDO73866.1 - 8e-42 138.0 17.6 2e-05 24.4 0.0 11.0 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_17 PF13431.6 CDO73866.1 - 2.7e-23 80.6 4.0 0.00021 21.5 0.0 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 CDO73866.1 - 2.9e-23 80.1 9.6 0.021 15.0 0.1 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 CDO73866.1 - 1.1e-22 80.1 15.1 0.0008 19.7 0.1 8.7 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 CDO73866.1 - 1.4e-20 72.7 9.5 7.4e-07 28.8 0.0 8.0 4 3 3 7 7 7 4 TPR repeat TPR_19 PF14559.6 CDO73866.1 - 2.8e-20 72.6 15.7 0.00021 21.7 0.0 6.8 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 CDO73866.1 - 1.4e-19 70.5 20.9 3.2e-07 30.9 0.2 6.8 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 CDO73866.1 - 2.7e-19 68.2 20.8 9.8e-06 26.0 0.0 9.0 6 4 3 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 CDO73866.1 - 9.2e-16 56.6 4.6 0.035 14.1 0.0 9.0 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 CDO73866.1 - 4.2e-13 49.2 11.8 0.0069 16.5 0.0 6.0 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 CDO73866.1 - 9.5e-09 35.1 5.4 1.3e-07 31.3 0.7 3.9 3 1 0 3 3 3 1 MalT-like TPR region ANAPC3 PF12895.7 CDO73866.1 - 1.2e-08 35.1 5.7 0.11 12.8 0.0 4.8 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CDO73866.1 - 2.2e-08 34.2 9.9 0.067 13.9 0.0 8.0 8 0 0 8 8 7 2 Tetratricopeptide repeat NARP1 PF12569.8 CDO73866.1 - 0.0027 16.7 0.0 0.0027 16.7 0.0 4.0 3 1 1 4 4 4 2 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 CDO73866.1 - 0.0094 15.8 16.4 13 5.8 0.1 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF3856 PF12968.7 CDO73866.1 - 0.01 15.9 0.7 3.9 7.6 0.1 4.4 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_20 PF14561.6 CDO73866.1 - 0.013 15.8 14.1 6 7.3 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDO73866.1 - 0.016 15.8 6.0 22 6.0 0.0 5.6 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF627 PF04781.12 CDO73866.1 - 0.049 13.7 0.2 0.74 9.9 0.0 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF627) Fis1_TPR_C PF14853.6 CDO73866.1 - 0.1 12.7 5.0 3 8.0 0.0 3.9 5 0 0 5 5 3 0 Fis1 C-terminal tetratricopeptide repeat Prolamin_like PF05617.11 CDO73866.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Prolamin-like SHNi-TPR PF10516.9 CDO73866.1 - 0.6 9.6 5.2 3.3 7.3 0.0 3.7 4 0 0 4 4 4 0 SHNi-TPR SPO22 PF08631.10 CDO73866.1 - 0.68 9.4 5.3 6 6.3 0.1 4.0 4 1 1 5 5 5 0 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 CDO73869.1 - 1.3e-08 35.0 22.6 0.001 19.7 0.1 9.0 7 2 3 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDO73869.1 - 2.2e-08 33.7 1.0 0.017 15.3 0.0 6.0 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDO73869.1 - 4.1e-07 29.6 7.1 5.1e-05 22.9 0.1 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDO73869.1 - 6.8e-07 28.9 18.9 0.0001 22.2 0.1 7.4 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDO73869.1 - 1e-05 25.6 0.0 0.054 13.9 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDO73869.1 - 0.00051 19.7 2.1 4.3 7.1 0.0 5.1 5 0 0 5 5 5 1 TPR repeat ANAPC3 PF12895.7 CDO73869.1 - 0.0026 17.9 0.1 6.9 7.0 0.0 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CDO73869.1 - 0.0055 17.2 9.5 2 9.0 0.1 5.0 6 1 0 6 6 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDO73869.1 - 0.0061 16.7 4.5 6 7.1 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDO73869.1 - 0.008 16.8 0.7 0.008 16.8 0.7 6.0 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDO73869.1 - 0.01 15.8 1.3 41 4.5 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 CDO73869.1 - 0.034 14.2 0.0 5.1 7.3 0.0 3.3 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_15 PF13429.6 CDO73869.1 - 0.043 13.0 0.2 0.043 13.0 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CAP_N PF01213.19 CDO73869.1 - 0.25 10.8 2.1 1 8.8 1.8 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TPR_12 PF13424.6 CDO73869.1 - 0.74 10.1 16.9 3.9 7.8 1.2 6.2 5 2 1 6 6 6 0 Tetratricopeptide repeat Mito_fiss_reg PF05308.11 CDO73869.1 - 8.7 6.3 7.0 3.1 7.8 1.3 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator PRIMA1 PF16101.5 CDO73869.1 - 9.4 6.3 6.8 2.3 8.3 2.9 1.9 2 0 0 2 2 1 0 Proline-rich membrane anchor 1 MGTL PF17059.5 CDO73871.1 - 4.6 7.2 6.7 0.76 9.7 1.2 2.6 2 0 0 2 2 2 0 MgtA leader peptide OCD_Mu_crystall PF02423.15 CDO73873.1 - 3.8e-24 85.2 2.2 5.9e-23 81.3 2.2 2.6 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 CDO73873.1 - 0.00065 19.8 0.0 0.035 14.2 0.0 2.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 CDO73874.1 - 6e-15 55.2 0.1 5.4e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Glyco_hydro_61 PF03443.14 CDO73875.1 - 7.3e-58 195.9 0.0 9.9e-58 195.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAD_binding_4 PF07993.12 CDO73876.1 - 5.4e-24 84.7 0.0 7.9e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CDO73876.1 - 1.9e-22 79.5 0.1 1.4e-11 43.6 0.0 3.0 3 0 0 3 3 3 2 AMP-binding enzyme Epimerase PF01370.21 CDO73876.1 - 7.9e-11 41.9 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDO73876.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 CDO73876.1 - 0.00013 22.2 0.1 0.00082 19.7 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 CDO73876.1 - 0.063 12.3 0.0 0.13 11.2 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 CDO73876.1 - 0.086 12.7 0.1 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 KR domain DUF4350 PF14258.6 CDO73876.1 - 0.1 13.0 0.0 10 6.6 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) NAD_binding_4 PF07993.12 CDO73877.1 - 4.2e-24 85.1 0.0 1e-23 83.8 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 CDO73877.1 - 2.9e-16 59.1 0.0 2.1e-07 29.9 0.0 2.6 2 1 1 3 3 3 2 AMP-binding enzyme Epimerase PF01370.21 CDO73877.1 - 2e-08 34.0 0.0 4.7e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CDO73877.1 - 0.0047 17.3 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 CDO73877.1 - 0.15 11.4 0.0 0.34 10.3 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Lectin_N PF03954.14 CDO73878.1 - 0.036 13.8 0.1 0.056 13.2 0.1 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Insulin_TMD PF17870.1 CDO73878.1 - 0.12 12.4 0.2 0.29 11.2 0.2 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment NUDIX_2 PF13869.6 CDO73879.1 - 2.9e-84 281.4 0.0 3.3e-84 281.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Abhydrolase_3 PF07859.13 CDO73880.1 - 4.6e-13 49.5 0.0 7.6e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 CDO73880.1 - 2.4e-07 30.0 0.2 2.3e-06 26.8 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CDO73880.1 - 0.012 16.2 0.3 0.016 15.9 0.3 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 CDO73880.1 - 0.031 13.1 0.0 0.52 9.1 0.0 2.4 2 1 0 2 2 2 0 Steryl acetyl hydrolase RhoGEF PF00621.20 CDO73881.1 - 6.5e-08 33.0 0.0 1.1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Sulfate_transp PF00916.20 CDO73882.1 - 5.3e-60 203.2 24.0 5.3e-60 203.2 24.0 1.5 2 0 0 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 CDO73882.1 - 9.7e-14 51.2 0.0 2.1e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 CDO73882.1 - 4.4e-09 36.0 0.1 8.7e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CDO73882.1 - 0.016 15.6 3.2 0.016 15.6 3.2 4.3 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily Cyt-b5 PF00173.28 CDO73883.1 - 2.3e-13 50.1 0.0 3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR_4 PF15892.5 CDO73884.1 - 2.3e-58 197.7 3.9 3.2e-58 197.2 3.9 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member SBBP PF06739.11 CDO73884.1 - 0.0013 18.6 1.0 0.015 15.3 1.0 2.4 2 0 0 2 2 2 1 Beta-propeller repeat DUF5124 PF17160.4 CDO73884.1 - 0.034 14.9 0.1 0.081 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5124) Zip PF02535.22 CDO73885.1 - 8.6e-32 110.7 3.5 9.9e-32 110.5 3.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter 7TM_GPCR_Srt PF10321.9 CDO73885.1 - 0.0091 15.0 0.3 0.14 11.2 0.0 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srt DUF4281 PF14108.6 CDO73885.1 - 0.04 14.3 3.5 0.039 14.3 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4281) DUF2116 PF09889.9 CDO73885.1 - 0.18 11.8 1.0 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3082 PF11282.8 CDO73885.1 - 0.22 11.8 0.0 0.22 11.8 0.0 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF3082) DUF2157 PF09925.9 CDO73885.1 - 0.38 10.5 4.9 0.39 10.5 3.3 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) CxC1 PF18802.1 CDO73886.1 - 0.0018 18.4 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases FbpA PF05833.11 CDO73886.1 - 0.14 10.9 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DDE_3 PF13358.6 CDO73887.1 - 1e-07 31.8 1.1 1.3e-07 31.5 1.0 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Plavaka PF18759.1 CDO73888.1 - 8e-33 114.0 0.0 9.6e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF908 PF06012.12 CDO73888.1 - 0.68 9.3 6.6 0.97 8.8 6.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4449 PF14613.6 CDO73889.1 - 2.1e-15 57.2 1.8 3e-15 56.7 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) DUF3069 PF11269.8 CDO73889.1 - 0.08 13.2 0.2 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) Pallilysin PF18663.1 CDO73889.1 - 0.6 10.1 2.2 0.61 10.1 0.3 1.9 2 0 0 2 2 2 0 Pallilysin beta barrel domain RNA_pol_Rpc82 PF05645.13 CDO73890.1 - 0.04 13.7 0.3 0.07 12.9 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 DEAD PF00270.29 CDO73892.1 - 7.9e-20 71.4 0.0 4.9e-17 62.2 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO73892.1 - 5.6e-14 52.4 0.0 3.2e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO73892.1 - 0.0015 18.5 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 CDO73892.1 - 0.074 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer RecQ_Zn_bind PF16124.5 CDO73892.1 - 0.09 13.5 0.8 0.26 12.0 0.8 1.8 1 0 0 1 1 1 0 RecQ zinc-binding SecA_DEAD PF07517.14 CDO73892.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain DUF563 PF04577.14 CDO73894.1 - 8.1e-18 65.3 0.3 2.2e-17 63.9 0.2 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF563) MA3 PF02847.17 CDO73894.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 MA3 domain OPT PF03169.15 CDO73896.1 - 2.2e-122 409.8 40.8 2.6e-122 409.5 40.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Bac_surface_Ag PF01103.23 CDO73898.1 - 1.6e-39 136.3 2.0 1.9e-39 136.1 2.0 1.1 1 0 0 1 1 1 1 Surface antigen MatE PF01554.18 CDO73899.1 - 3e-37 127.8 16.5 6.8e-25 87.6 8.8 2.6 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 CDO73899.1 - 1e-06 28.9 7.7 1e-06 28.9 7.7 3.1 1 1 2 3 3 3 2 Polysaccharide biosynthesis C-terminal domain MFS_1 PF07690.16 CDO73900.1 - 4e-15 55.6 21.6 7.5e-15 54.7 21.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily CRIM PF16978.5 CDO73901.1 - 6.1e-43 146.3 0.0 1.4e-42 145.2 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 CDO73901.1 - 4.8e-24 84.8 1.2 5.4e-24 84.6 0.1 1.6 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 CDO73901.1 - 7e-05 23.0 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain RA PF00788.23 CDO73901.1 - 0.00071 20.2 0.0 0.0042 17.7 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain RBD PF02196.15 CDO73901.1 - 0.0026 17.8 0.0 0.023 14.7 0.0 2.2 2 0 0 2 2 2 1 Raf-like Ras-binding domain FERM_N PF09379.10 CDO73901.1 - 0.023 14.7 0.0 0.084 12.8 0.0 1.8 2 0 0 2 2 2 0 FERM N-terminal domain F-box-like PF12937.7 CDO73902.1 - 2.9e-11 43.1 1.4 5.6e-11 42.2 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDO73902.1 - 2.6e-09 36.7 0.1 6.5e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CDO73902.1 - 0.0078 16.1 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 F-box Cwf_Cwc_15 PF04889.12 CDO73902.1 - 9.6 5.9 11.3 0.13 12.0 0.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_S8 PF00410.19 CDO73903.1 - 4.3e-11 42.9 0.0 3.2e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 DUF3484 PF11983.8 CDO73904.1 - 0.03 15.4 0.2 0.03 15.4 0.2 4.3 5 0 0 5 5 5 0 Membrane-attachment and polymerisation-promoting switch Usp PF00582.26 CDO73904.1 - 0.87 10.1 4.9 3.1 8.3 0.0 3.5 3 0 0 3 3 3 0 Universal stress protein family DcpS PF05652.12 CDO73905.1 - 2.9e-27 95.5 0.0 5.2e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 CDO73905.1 - 6.6e-18 65.3 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Metallophos PF00149.28 CDO73906.1 - 3.6e-16 60.3 1.0 1.7e-15 58.1 0.4 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDO73906.1 - 1.4e-05 25.4 0.0 0.00011 22.4 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PBP1_TM PF14812.6 CDO73907.1 - 2.5 8.5 7.0 0.28 11.6 0.4 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 CDO73908.1 - 0.042 12.2 10.3 0.06 11.6 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDO73908.1 - 6.9 6.4 11.3 13 5.5 11.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 3-HAO PF06052.12 CDO73909.1 - 1.5e-57 193.5 0.0 1.7e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 CDO73909.1 - 7e-08 32.1 0.1 1.1e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CDO73909.1 - 0.0035 17.3 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CDO73909.1 - 0.01 15.4 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Cupin A2L_zn_ribbon PF08792.10 CDO73909.1 - 0.045 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain DZR PF12773.7 CDO73909.1 - 0.091 12.8 0.5 0.19 11.8 0.2 1.7 2 0 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CDO73909.1 - 0.098 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Rad17 PF03215.15 CDO73910.1 - 1.2e-26 93.8 0.0 1.3e-21 77.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_assoc_2 PF16193.5 CDO73910.1 - 0.0054 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 CDO73910.1 - 0.013 15.8 0.0 0.45 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDO73910.1 - 0.019 15.4 0.1 0.084 13.2 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 CDO73910.1 - 0.027 14.9 0.0 0.084 13.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CDO73910.1 - 0.07 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 CDO73910.1 - 0.095 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 CDO73910.1 - 0.16 12.6 0.0 0.42 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Spc7_N PF15402.6 CDO73912.1 - 0.054 11.8 5.2 0.063 11.5 5.2 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Med15 PF09606.10 CDO73912.1 - 1 8.0 13.6 1.1 7.9 13.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-RRN7 PF11781.8 CDO73913.1 - 0.013 15.2 1.7 0.027 14.2 1.7 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-C2H2_4 PF13894.6 CDO73913.1 - 0.18 12.7 0.2 0.18 12.7 0.2 3.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CDO73914.1 - 0.46 11.4 10.0 0.6 11.1 0.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDO73914.1 - 4.1 8.0 12.9 1.4 9.5 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type ketoacyl-synt PF00109.26 CDO73915.1 - 5.3e-79 265.4 0.5 4.5e-78 262.3 0.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 CDO73915.1 - 3.7e-41 141.7 0.0 7.9e-41 140.6 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 CDO73915.1 - 7.4e-37 126.0 1.1 1.8e-36 124.7 1.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 CDO73915.1 - 4.6e-24 85.2 0.1 7.9e-24 84.4 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 CDO73915.1 - 3.7e-22 78.5 1.6 6.3e-13 48.9 0.1 3.0 2 1 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 CDO73915.1 - 3.3e-17 63.4 0.2 1.9e-16 60.9 0.0 2.3 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 CDO73915.1 - 5.5e-08 33.7 1.2 5.5e-08 33.7 1.2 4.0 2 1 1 3 3 3 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 CDO73915.1 - 7.4e-05 23.2 0.0 0.00019 21.8 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 CDO73915.1 - 0.00011 21.7 0.1 0.00025 20.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF659 PF04937.15 CDO73916.1 - 3.7e-12 46.3 0.0 7.5e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CDO73916.1 - 0.0016 18.1 0.6 0.0047 16.7 0.6 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AAA_16 PF13191.6 CDO73916.1 - 0.023 15.1 0.1 0.082 13.3 0.1 2.0 1 0 0 1 1 1 0 AAA ATPase domain Transposase_21 PF02992.14 CDO73917.1 - 3.1e-14 52.7 0.1 6.2e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 CDO73917.1 - 0.00029 20.4 0.2 0.00062 19.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1258) DUF724 PF05266.14 CDO73917.1 - 0.041 13.7 9.2 0.089 12.6 9.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HMMR_N PF15905.5 CDO73917.1 - 0.089 12.2 10.3 0.14 11.6 10.3 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4218 PF13960.6 CDO73917.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Jnk-SapK_ap_N PF09744.9 CDO73917.1 - 0.15 12.2 9.4 0.42 10.8 9.4 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FAM76 PF16046.5 CDO73917.1 - 0.29 10.5 3.1 0.57 9.5 3.1 1.4 1 0 0 1 1 1 0 FAM76 protein Lectin_N PF03954.14 CDO73917.1 - 0.41 10.4 3.6 1.2 8.9 3.6 1.8 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain EzrA PF06160.12 CDO73917.1 - 0.48 8.5 11.6 1.1 7.3 11.6 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1319 PF07028.11 CDO73917.1 - 0.49 10.6 3.1 4 7.7 3.1 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) Fib_alpha PF08702.10 CDO73917.1 - 1.1 9.4 7.8 2.2 8.4 7.8 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.13 CDO73917.1 - 5.9 6.7 9.0 0.6 9.9 0.3 2.7 1 1 1 2 2 2 0 Nsp1-like C-terminal region SlyX PF04102.12 CDO73917.1 - 7.2 7.3 10.6 0.31 11.7 2.2 3.0 3 0 0 3 3 3 0 SlyX Sad1_UNC PF07738.13 CDO73919.1 - 5.4e-11 42.6 0.0 6.1e-05 23.0 0.0 2.6 1 1 0 2 2 2 2 Sad1 / UNC-like C-terminal HSP20 PF00011.21 CDO73921.1 - 6.7e-23 80.8 0.4 8.3e-23 80.5 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDO73921.1 - 2.2e-09 36.7 0.0 4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA zf-C2H2_4 PF13894.6 CDO73922.1 - 0.00031 21.3 8.0 0.013 16.2 0.8 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 CDO73922.1 - 0.0035 17.6 3.1 0.061 13.6 0.4 2.5 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CDO73922.1 - 0.028 14.9 10.7 0.089 13.3 0.9 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type CDC45 PF02724.14 CDO73922.1 - 0.26 9.6 5.1 0.33 9.2 5.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 CDO73922.1 - 2.5 6.8 5.6 0.22 10.3 1.1 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 zf-MIZ PF02891.20 CDO73922.1 - 3.9 7.3 7.3 3.3 7.5 5.0 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Glyco_trans_2_3 PF13632.6 CDO73923.1 - 5.7e-58 196.1 0.9 5.7e-58 196.1 0.9 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CDO73923.1 - 3.9e-05 23.6 0.0 6.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CDO73923.1 - 0.0015 18.4 0.0 0.018 14.9 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CDO73923.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 CDO73924.1 - 4.3e-21 75.2 0.9 7.9e-21 74.3 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 UBA_e1_thiolCys PF10585.9 CDO73925.1 - 2.7e-11 43.9 0.1 6e-10 39.5 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 CDO73925.1 - 5.8e-06 26.8 0.1 2e-05 25.1 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain ThiF PF00899.21 CDO73925.1 - 1.3e-05 24.6 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family HSP20 PF00011.21 CDO73926.1 - 2.4e-22 79.0 0.2 2.9e-22 78.8 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDO73926.1 - 3.5e-07 29.7 0.0 6.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HMA PF00403.26 CDO73926.1 - 0.0043 17.5 0.0 0.14 12.7 0.0 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain CS PF04969.16 CDO73926.1 - 0.16 13.0 0.1 0.42 11.7 0.1 1.8 1 1 0 1 1 1 0 CS domain zf-primase PF09329.11 CDO73927.1 - 6.5e-17 61.1 4.2 1.3e-16 60.1 4.2 1.6 1 0 0 1 1 1 1 Primase zinc finger VirK PF06903.12 CDO73927.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 VirK protein SPX PF03105.19 CDO73928.1 - 1.2e-36 127.5 0.5 3.1e-36 126.1 0.5 1.7 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 CDO73928.1 - 1.9e-07 30.8 6.8 3e-07 30.2 6.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO73928.1 - 8.3e-06 25.6 8.5 1.3e-05 24.9 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO73928.1 - 1.3e-05 25.4 9.6 2.1e-05 24.8 9.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CDO73928.1 - 2.3e-05 24.4 7.6 4.1e-05 23.6 7.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDO73928.1 - 0.00016 21.6 8.5 0.00027 20.8 8.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CDO73928.1 - 0.00027 20.8 8.3 0.00046 20.0 8.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CDO73928.1 - 0.00054 19.7 8.8 0.00088 19.1 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO73928.1 - 0.0046 16.9 3.8 0.0046 16.9 3.8 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 CDO73928.1 - 0.034 14.3 4.6 0.065 13.4 4.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CDO73928.1 - 0.052 13.3 6.8 0.1 12.4 6.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CDO73928.1 - 0.061 13.6 4.7 0.12 12.7 4.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF4936 PF16290.5 CDO73928.1 - 0.094 13.4 0.2 0.68 10.7 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4936) zf-RING_6 PF14835.6 CDO73928.1 - 0.12 12.3 3.8 0.22 11.4 3.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 CDO73928.1 - 0.28 10.9 5.2 0.57 9.9 5.2 1.5 1 0 0 1 1 1 0 P-11 zinc finger ThiF PF00899.21 CDO73930.1 - 1.5e-11 44.1 0.0 1.1e-10 41.3 0.0 2.0 1 1 0 1 1 1 1 ThiF family NAT PF04768.13 CDO73931.1 - 4.5e-47 159.9 0.0 7.7e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 CDO73931.1 - 8.8e-29 100.4 0.0 2.1e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 CDO73931.1 - 4.9e-25 88.5 0.1 9.1e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.18 CDO73931.1 - 0.00013 22.1 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Myosin_head PF00063.21 CDO73933.1 - 1.6e-258 859.5 0.0 1.6e-257 856.2 0.0 2.7 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CDO73933.1 - 1.5e-24 86.0 314.8 5.9e-16 57.5 148.7 6.1 1 1 2 5 5 5 4 Myosin tail Myosin_N PF02736.19 CDO73933.1 - 2.3e-09 36.9 3.2 7.3e-09 35.3 3.2 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CDO73933.1 - 0.016 15.5 0.0 0.016 15.5 0.0 6.9 7 2 2 9 9 9 0 AAA domain TsaE PF02367.17 CDO73933.1 - 0.05 13.6 0.0 1.3 9.0 0.0 3.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ribosomal_L38e PF01781.18 CDO73934.1 - 3e-33 113.7 0.9 3.5e-33 113.5 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Synaptobrevin PF00957.21 CDO73935.1 - 3.5e-14 52.4 0.9 5.7e-14 51.7 0.9 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CDO73935.1 - 1.8e-12 47.1 0.0 3.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain E1-E2_ATPase PF00122.20 CDO73936.1 - 6.1e-24 84.5 0.1 1.3e-23 83.5 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CDO73936.1 - 2.6e-16 60.6 0.0 3.1e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDO73936.1 - 4.8e-05 23.4 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDO73936.1 - 0.016 14.9 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glucos_trans_II PF14264.6 CDO73936.1 - 0.16 11.3 10.4 0.067 12.5 0.8 2.9 3 0 0 3 3 3 0 Glucosyl transferase GtrII zf-RING_2 PF13639.6 CDO73937.1 - 1.5e-12 47.6 7.2 2.3e-12 47.0 7.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CDO73937.1 - 2.7e-08 34.0 5.5 4.9e-08 33.1 5.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CDO73937.1 - 4.4e-08 33.0 3.8 8e-08 32.2 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDO73937.1 - 7.1e-07 29.0 6.3 1.1e-06 28.3 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDO73937.1 - 3.6e-06 26.6 2.5 6.7e-06 25.7 2.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CDO73937.1 - 1.2e-05 25.1 4.1 1.8e-05 24.5 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO73937.1 - 1.6e-05 24.8 3.6 2.4e-05 24.2 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDO73937.1 - 6.1e-05 22.8 3.9 9.5e-05 22.2 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDO73937.1 - 0.00021 21.3 3.0 0.00041 20.3 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CDO73937.1 - 0.0096 15.8 5.7 0.14 12.0 6.1 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 CDO73937.1 - 0.095 12.8 7.4 0.17 12.1 7.4 1.4 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 CDO73937.1 - 0.12 12.2 0.5 0.27 11.1 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 CDO73937.1 - 0.19 11.9 3.4 0.4 10.9 3.4 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 CDO73937.1 - 0.39 10.6 5.0 0.7 9.8 5.0 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 CDO73937.1 - 1.3 8.7 5.1 2.2 8.0 5.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 CDO73937.1 - 3.9 7.3 6.1 6.5 6.6 6.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Metallophos PF00149.28 CDO73939.1 - 0.0004 20.9 0.0 0.00085 19.9 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UQ_con PF00179.26 CDO73940.1 - 1.4e-36 125.2 0.0 1.6e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDO73940.1 - 0.00073 19.2 0.0 0.00095 18.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CDO73940.1 - 0.018 14.9 0.1 0.038 13.9 0.1 1.5 1 1 0 1 1 1 0 UEV domain SCF PF02404.15 CDO73941.1 - 0.013 14.9 0.0 0.014 14.7 0.0 1.0 1 0 0 1 1 1 0 Stem cell factor ERG4_ERG24 PF01222.17 CDO73942.1 - 0.044 12.5 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family NOA36 PF06524.12 CDO73946.1 - 0.31 10.3 5.0 0.4 9.9 5.0 1.1 1 0 0 1 1 1 0 NOA36 protein KAR9 PF08580.10 CDO73946.1 - 2 6.9 6.2 2.8 6.4 6.2 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Methyltransf_2 PF00891.18 CDO73947.1 - 5.9e-11 42.1 0.0 2.2e-10 40.2 0.0 1.9 2 1 0 2 2 2 1 O-methyltransferase domain DUF938 PF06080.12 CDO73947.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Aldo_ket_red PF00248.21 CDO73949.1 - 2.5e-07 30.2 0.0 3.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Plavaka PF18759.1 CDO73950.1 - 3e-118 394.8 0.0 4.8e-118 394.1 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Aldo_ket_red PF00248.21 CDO73951.1 - 2e-48 165.1 0.0 2.6e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NT5C PF06941.12 CDO73951.1 - 0.099 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF4455 PF14643.6 CDO73951.1 - 0.25 10.0 0.0 0.36 9.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Peptidase_S10 PF00450.22 CDO73952.1 - 2.6e-19 69.9 0.0 6.6e-17 62.0 0.0 2.3 1 1 0 1 1 1 1 Serine carboxypeptidase HRDC PF00570.23 CDO73953.1 - 0.07 13.1 1.1 0.13 12.3 1.1 1.4 1 0 0 1 1 1 0 HRDC domain Retrotrans_gag PF03732.17 CDO73954.1 - 1.1e-12 48.0 0.1 3.7e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO73954.1 - 6.9e-09 35.6 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Apt1 PF10351.9 CDO73954.1 - 2.2 7.1 7.1 3.4 6.4 7.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM199X PF15814.5 CDO73954.1 - 2.6 7.0 10.5 4.1 6.4 10.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X NPR3 PF03666.13 CDO73954.1 - 4.3 6.0 5.5 7.3 5.3 5.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SOG2 PF10428.9 CDO73954.1 - 5.8 6.0 22.8 2 7.5 9.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein RVT_1 PF00078.27 CDO73955.1 - 9.4e-17 61.3 0.0 2e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO73955.1 - 3e-09 36.8 0.1 6.8e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDO73955.1 - 1e-05 25.2 0.1 3.5e-05 23.4 0.1 2.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HIP1_clath_bdg PF16515.5 CDO73956.1 - 0.0079 16.8 2.4 0.016 15.8 2.4 1.4 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3716 PF12511.8 CDO73956.1 - 0.012 15.6 13.5 0.022 14.8 6.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) NolB PF17398.2 CDO73956.1 - 0.11 12.8 1.8 3.1 8.2 0.4 2.4 1 1 1 2 2 2 0 Nodulation protein NolB Prenyltrans PF00432.21 CDO73956.1 - 0.14 11.9 0.1 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat CLZ PF16526.5 CDO73956.1 - 0.16 12.3 0.8 8.5 6.8 1.1 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ARGLU PF15346.6 CDO73956.1 - 0.96 9.3 7.0 1.7 8.5 7.0 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 zinc_ribbon_10 PF10058.9 CDO73956.1 - 5.3 6.9 7.8 0.36 10.6 2.5 1.7 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Cauli_VI PF01693.16 CDO73957.1 - 1.6e-11 44.3 0.1 8e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin 2OG-FeII_Oxy_3 PF13640.6 CDO73958.1 - 0.034 15.1 0.0 0.084 13.8 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily KDZ PF18758.1 CDO73959.1 - 4.8e-50 170.2 0.0 8e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 CDO73959.1 - 2.1e-38 130.8 0.0 3.9e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 CDO73959.1 - 1.5e-05 25.1 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 CDO73959.1 - 0.00051 19.9 0.0 0.00099 18.9 0.0 1.5 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases APC_u13 PF16634.5 CDO73960.1 - 0.37 10.7 3.9 0.68 9.9 3.1 1.9 1 1 1 2 2 2 0 Unstructured region on APC between APC_crr and SAMP Pkinase_fungal PF17667.1 CDO73963.1 - 3.7e-23 82.0 0.0 1.3e-22 80.2 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase DUF3716 PF12511.8 CDO73964.1 - 0.02 14.9 14.2 0.023 14.8 7.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) HIP1_clath_bdg PF16515.5 CDO73964.1 - 0.11 13.1 5.1 0.22 12.2 4.3 1.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 CDO73964.1 - 0.12 12.4 0.4 0.25 11.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 CDO73964.1 - 0.32 11.3 4.0 0.22 11.8 1.1 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 NolB PF17398.2 CDO73964.1 - 0.39 11.1 2.0 19 5.6 0.4 2.7 1 1 1 2 2 2 0 Nodulation protein NolB ARGLU PF15346.6 CDO73964.1 - 8.9 6.2 9.3 20 5.0 9.3 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Pkinase_fungal PF17667.1 CDO73965.1 - 2.9e-56 191.0 0.0 6.6e-56 189.8 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CDO73965.1 - 0.033 13.5 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 CDO73966.1 - 2.8e-38 132.2 0.0 5e-38 131.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO73966.1 - 1.8e-05 24.4 0.0 2.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 CDO73966.1 - 0.0011 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_fungal PF17667.1 CDO73967.1 - 2e-18 66.4 0.1 4.3e-10 39.0 0.1 2.7 2 1 1 3 3 3 2 Fungal protein kinase ATPgrasp_ST PF14397.6 CDO73967.1 - 0.18 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ADPRTs_Tse2 PF18648.1 CDO73968.1 - 0.032 14.3 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins Pectinesterase PF01095.19 CDO73971.1 - 1.4e-36 125.7 0.5 3.2e-31 108.1 0.4 2.0 2 0 0 2 2 2 2 Pectinesterase DUF202 PF02656.15 CDO73972.1 - 1.8e-17 63.5 1.7 1.8e-17 63.5 1.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Pkinase PF00069.25 CDO73973.1 - 6.3e-69 232.3 0.0 8.6e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO73973.1 - 3.7e-42 144.4 0.0 5.1e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO73973.1 - 4.1e-09 36.2 0.0 9e-09 35.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CDO73973.1 - 0.016 15.1 0.3 1.9 8.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CDO73973.1 - 0.051 13.2 0.0 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDO73973.1 - 0.052 12.9 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CDO73973.1 - 0.071 12.1 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_M16 PF00675.20 CDO73974.1 - 2.1e-53 180.3 0.2 3.8e-53 179.5 0.2 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDO73974.1 - 1e-22 81.1 0.2 3e-11 43.7 0.0 4.1 3 1 1 4 4 4 3 Peptidase M16 inactive domain Metal_resist PF13801.6 CDO73974.1 - 0.059 13.6 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 Heavy-metal resistance DUF725 PF05267.12 CDO73974.1 - 0.089 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) MTD PF01993.18 CDO73974.1 - 0.11 11.8 0.0 2.6 7.3 0.0 2.2 1 1 1 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase CoA_transf_3 PF02515.17 CDO73975.1 - 4.7e-48 164.2 0.3 1.3e-41 142.9 0.1 2.4 2 1 0 2 2 2 2 CoA-transferase family III ETF PF01012.21 CDO73976.1 - 7.1e-43 146.6 2.3 9.5e-43 146.2 2.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETC_C1_NDUFA4 PF04800.12 CDO73977.1 - 4e-12 46.2 0.1 4.7e-12 46.0 0.1 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF3276 PF11680.8 CDO73977.1 - 0.054 13.6 0.0 0.059 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Retrotran_gag_2 PF14223.6 CDO73979.1 - 5.4e-17 61.8 0.0 1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CDO73979.1 - 3.6e-08 32.9 0.4 8.7e-08 31.7 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) FMN_bind_2 PF04299.12 CDO73979.1 - 0.12 12.1 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Putative FMN-binding domain XRN_N PF03159.18 CDO73979.1 - 0.89 8.9 3.4 1.9 7.8 1.7 2.0 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Dimer_Tnp_hAT PF05699.14 CDO73980.1 - 2.2e-06 27.4 0.0 5.6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4646 PF15496.6 CDO73981.1 - 5e-09 36.8 0.0 7.2e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4646) XRN_M PF17846.1 CDO73982.1 - 2e-145 485.1 0.6 6.2e-107 358.3 0.1 2.4 3 0 0 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 CDO73982.1 - 1.1e-99 332.7 0.0 1.7e-99 332.2 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 CDO73982.1 - 0.00026 20.9 2.4 0.00051 20.0 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDO73982.1 - 0.014 15.3 0.8 0.025 14.5 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 CDO73982.1 - 0.038 13.8 1.6 0.081 12.8 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1947 PF09183.10 CDO73982.1 - 0.092 13.1 0.1 1.5 9.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Vps52 PF04129.12 CDO73982.1 - 0.36 9.5 0.4 2 7.0 1.3 1.6 2 0 0 2 2 2 0 Vps52 / Sac2 family IF-2B PF01008.17 CDO73983.1 - 1.6e-85 286.8 0.1 1.9e-85 286.5 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Med14 PF08638.11 CDO73983.1 - 0.13 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit MED14 MTP18 PF10558.9 CDO73984.1 - 5.9e-50 169.6 5.0 7.4e-49 166.0 5.0 2.1 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Forkhead PF00250.18 CDO73985.1 - 3.8e-25 87.9 0.0 6.1e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CDO73985.1 - 1.6e-07 31.6 0.0 2.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain IPK PF03770.16 CDO73987.1 - 1e-37 130.0 0.0 2e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Abhydrolase_1 PF00561.20 CDO73988.1 - 5.3e-23 82.0 0.0 1.7e-22 80.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO73988.1 - 3e-17 62.7 0.0 3.5e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO73988.1 - 2.4e-15 57.7 2.5 2.4e-15 57.7 2.5 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ribosomal_S11 PF00411.19 CDO73988.1 - 1.6e-07 31.7 0.0 3.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Esterase PF00756.20 CDO73988.1 - 2.8e-05 23.9 0.0 5.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 CDO73988.1 - 0.0009 18.9 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 CDO73988.1 - 0.0012 18.7 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold UPF0227 PF05728.12 CDO73988.1 - 0.0086 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.13 CDO73988.1 - 0.024 14.5 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Ndr PF03096.14 CDO73988.1 - 0.072 11.8 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 Ndr family BAAT_C PF08840.11 CDO73988.1 - 0.09 12.7 0.0 4 7.3 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Syntaxin-5_N PF11416.8 CDO73989.1 - 0.11 11.8 0.2 0.21 10.8 0.2 1.5 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain MFS_1 PF07690.16 CDO73990.1 - 2.5e-26 92.5 79.6 3.6e-20 72.2 47.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Iso_dh PF00180.20 CDO73991.1 - 2.3e-100 336.2 0.0 2.6e-100 336.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-MYND PF01753.18 CDO73994.1 - 0.0067 16.5 8.4 0.019 15.1 8.4 1.8 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CDO73994.1 - 0.32 11.3 8.6 1.1 9.6 8.6 1.9 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 CDO73994.1 - 0.54 10.4 3.0 1.8 8.7 3.0 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 WD40 PF00400.32 CDO73995.1 - 2.9e-23 81.7 10.2 2.2e-06 28.3 0.4 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO73995.1 - 2.2e-09 37.5 0.3 0.00056 20.1 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO73995.1 - 0.011 14.7 0.0 0.096 11.6 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ASH PF15780.5 CDO73995.1 - 0.068 13.4 0.1 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin eIF2A PF08662.11 CDO73995.1 - 0.12 12.3 0.0 17 5.3 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Arf PF00025.21 CDO73996.1 - 2.3e-70 235.6 0.0 2.7e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CDO73996.1 - 2.3e-14 53.3 0.0 3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CDO73996.1 - 1.4e-13 51.1 0.0 1.9e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CDO73996.1 - 2.5e-13 49.9 0.1 1.1e-08 34.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CDO73996.1 - 2.4e-10 40.3 0.0 2.4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CDO73996.1 - 1.2e-08 34.6 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CDO73996.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CDO73996.1 - 0.062 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF2373 PF10180.9 CDO73997.1 - 1.4e-20 72.9 0.2 1.4e-20 72.9 0.2 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) EndoU_bacteria PF14436.6 CDO73997.1 - 0.017 15.4 0.5 0.049 14.0 0.5 1.8 1 0 0 1 1 1 0 Bacterial EndoU nuclease Aminotran_1_2 PF00155.21 CDO73998.1 - 3.8e-74 250.1 0.0 4.9e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CDO73998.1 - 8.9e-05 21.6 0.0 0.00039 19.5 0.0 1.7 1 1 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CDO73998.1 - 0.00025 19.7 0.0 0.00044 18.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 CDO73999.1 - 1.1e-97 327.3 0.0 1.6e-97 326.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III cwf21 PF08312.12 CDO74000.1 - 4.9e-15 55.4 12.5 4.9e-15 55.4 12.5 2.7 2 1 0 2 2 2 1 cwf21 domain PA28_alpha PF02251.18 CDO74000.1 - 0.055 13.5 0.4 0.12 12.5 0.4 1.5 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Flavokinase PF01687.17 CDO74001.1 - 4.3e-28 97.8 0.0 5.7e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase TAF8_C PF10406.9 CDO74002.1 - 1e-09 38.8 3.2 1e-09 38.8 3.2 2.3 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 CDO74002.1 - 1.5e-08 34.5 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Myb_DNA-binding PF00249.31 CDO74003.1 - 7.3e-52 173.3 6.3 1.3e-13 50.9 0.1 5.5 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDO74003.1 - 2.5e-37 126.9 0.4 3.5e-12 46.4 0.2 5.3 2 2 3 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 CDO74003.1 - 6.6e-06 26.1 0.0 0.0087 16.1 0.0 2.7 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 CDO74003.1 - 1.9e-05 25.0 6.2 0.079 13.3 0.0 5.1 5 1 0 5 5 5 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 CDO74003.1 - 0.0065 16.5 0.3 4.8 7.3 0.1 2.6 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 CDO74003.1 - 0.041 13.8 0.0 31 4.6 0.0 3.4 1 1 2 3 3 3 0 Myb DNA-binding like TBCA PF02970.16 CDO74003.1 - 0.32 11.3 2.8 1.3 9.4 2.8 2.1 1 0 0 1 1 1 0 Tubulin binding cofactor A RAP1 PF07218.11 CDO74003.1 - 1.7 6.8 2.5 2.4 6.3 2.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TMEM208_SND2 PF05620.11 CDO74004.1 - 5.7e-58 195.4 0.0 6.5e-58 195.2 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 RVT_2 PF07727.14 CDO74006.1 - 1.2e-67 228.1 0.0 1.6e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO74006.1 - 9.8e-08 32.2 0.9 6.2e-07 29.6 0.2 2.3 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDO74006.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain NmrA PF05368.13 CDO74008.1 - 4.5e-19 68.9 0.0 6.8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CDO74008.1 - 2.2e-18 66.8 0.0 5.4e-18 65.5 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CDO74008.1 - 0.023 13.7 0.0 0.13 11.3 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MT-A70 PF05063.14 CDO74009.1 - 1.2e-52 178.4 0.1 1.7e-52 177.8 0.1 1.3 1 0 0 1 1 1 1 MT-A70 Mo-nitro_C PF06967.11 CDO74009.1 - 0.0026 17.7 0.0 0.56 10.2 0.0 2.3 2 0 0 2 2 2 2 Mo-dependent nitrogenase C-terminus TetR_C_7 PF14246.6 CDO74009.1 - 0.14 12.2 0.0 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain GST_N PF02798.20 CDO74010.1 - 3.3e-14 53.0 0.0 5.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CDO74010.1 - 1.8e-11 44.3 0.0 4.8e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDO74010.1 - 1.3e-10 41.3 0.0 2.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CDO74010.1 - 4.5e-10 39.7 0.0 9.9e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDO74010.1 - 2.2e-05 24.5 0.0 5.5e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO74010.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF836 PF05768.14 CDO74010.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GCV_T PF01571.21 CDO74011.1 - 2.7e-06 27.0 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain WD40 PF00400.32 CDO74012.1 - 8.5e-22 77.1 12.4 3.4e-05 24.5 0.3 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO74012.1 - 4.5e-08 33.3 0.1 0.26 11.6 0.0 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO74012.1 - 0.0076 15.3 0.0 3.1 6.7 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DEAD PF00270.29 CDO74013.1 - 5.4e-15 55.6 0.0 1.3e-14 54.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO74013.1 - 6.4e-08 32.9 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.22 CDO74014.1 - 7.3e-12 44.9 0.0 5.5e-06 26.1 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 CDO74014.1 - 0.032 14.2 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Cas6 PF09559.10 CDO74014.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Cas6 Crispr LSM PF01423.22 CDO74015.1 - 1.1e-21 76.3 0.0 1.3e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDO74015.1 - 0.0052 16.9 0.0 0.0064 16.6 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain PfkB PF00294.24 CDO74016.1 - 2.9e-09 36.7 0.3 3.9e-09 36.3 0.3 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DPBB_1 PF03330.18 CDO74017.1 - 0.00012 22.3 0.0 0.00017 21.8 0.0 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CDO74017.1 - 0.035 14.0 0.1 0.048 13.5 0.1 1.3 1 0 0 1 1 1 0 Barwin family ACPS PF01648.20 CDO74018.1 - 1.1e-12 48.1 0.0 1.7e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ARD PF03079.14 CDO74019.1 - 0.013 15.7 1.5 0.024 14.8 1.5 1.3 1 0 0 1 1 1 0 ARD/ARD' family Spc7 PF08317.11 CDO74019.1 - 0.02 13.8 1.4 0.029 13.3 1.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_int_SAM_2 PF12834.7 CDO74019.1 - 0.075 13.7 0.6 0.17 12.6 0.3 1.7 1 1 0 1 1 1 0 Phage integrase, N-terminal TAN PF11640.8 CDO74019.1 - 0.079 13.1 0.2 3.2 7.9 0.0 2.4 1 1 1 2 2 2 0 Telomere-length maintenance and DNA damage repair tRNA-synt_2 PF00152.20 CDO74020.1 - 2.7e-86 289.5 0.0 4.2e-42 144.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CDO74020.1 - 0.056 12.9 0.0 1.2 8.6 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Asp PF00026.23 CDO74021.1 - 6.3e-66 222.9 1.1 7.5e-66 222.7 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO74021.1 - 1.2e-16 61.5 0.6 3.2e-14 53.6 0.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 CDO74021.1 - 0.00015 22.3 0.8 0.0013 19.2 0.0 2.9 4 0 0 4 4 4 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO74021.1 - 0.00017 22.2 0.7 0.013 16.1 0.1 2.9 2 1 0 2 2 2 1 Aspartyl protease zf-MYND PF01753.18 CDO74022.1 - 2.9e-10 40.0 9.7 6.3e-10 39.0 9.7 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CDO74022.1 - 0.0032 17.8 7.5 0.0056 17.0 6.8 1.8 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding TPR_14 PF13428.6 CDO74022.1 - 0.02 15.7 6.8 3.2 8.8 0.5 4.6 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDO74022.1 - 0.3 11.4 1.7 54 4.2 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDO74022.1 - 0.41 11.2 2.0 9.1 6.9 0.3 3.2 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CDO74022.1 - 0.45 10.7 3.7 45 4.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDO74022.1 - 0.5 11.1 5.1 0.94 10.2 0.5 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Meleagrin PF08189.11 CDO74022.1 - 3.2 7.5 7.4 19 5.1 2.5 2.5 1 1 1 2 2 2 0 Meleagrin/Cygnin family F-box-like PF12937.7 CDO74023.1 - 0.00019 21.2 0.7 0.00051 19.9 0.7 1.8 1 0 0 1 1 1 1 F-box-like Ribosomal_L19 PF01245.20 CDO74024.1 - 1.7e-08 34.4 0.5 1.4e-07 31.4 0.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L19 Fungal_trans PF04082.18 CDO74025.1 - 1.9e-34 118.9 0.0 2.6e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.24 CDO74026.1 - 9.6e-30 103.8 0.3 9.6e-30 103.8 0.3 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DDE_1 PF03184.19 CDO74026.1 - 3.4e-19 69.2 0.0 6.5e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Acyl-CoA_dh_M PF02770.19 CDO74026.1 - 8.6e-17 61.1 0.0 2.2e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CDO74026.1 - 9.6e-11 42.1 0.5 9.6e-11 42.1 0.5 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CDO74026.1 - 9.2e-10 39.2 0.0 9.2e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HTH_Tnp_Tc5 PF03221.16 CDO74026.1 - 4.6e-08 33.0 0.0 1.4e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain SAP PF02037.27 CDO74026.1 - 0.0019 17.9 0.2 0.028 14.2 0.0 2.5 2 0 0 2 2 2 1 SAP domain DDE_3 PF13358.6 CDO74026.1 - 0.0028 17.4 0.1 0.0076 16.0 0.1 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease SL4P PF17618.2 CDO74026.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein MRP-S26 PF14943.6 CDO74028.1 - 0.0047 16.9 0.9 0.0059 16.5 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosome subunit S26 DUF2423 PF10338.9 CDO74029.1 - 1.2e-15 57.5 4.2 1.6e-15 57.0 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Laps PF10169.9 CDO74029.1 - 0.028 15.0 2.3 0.044 14.4 2.3 1.4 1 1 0 1 1 1 0 Learning-associated protein BOP1NT PF08145.12 CDO74031.1 - 2.8e-104 348.7 7.3 4.1e-104 348.1 7.3 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CDO74031.1 - 9e-20 70.6 5.8 0.00011 23.0 0.1 5.6 5 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO74031.1 - 1.7e-06 28.2 0.2 0.016 15.5 0.1 4.2 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 CDO74031.1 - 0.062 12.7 14.1 0.09 12.2 14.1 1.2 1 0 0 1 1 1 0 SDA1 Actin PF00022.19 CDO74032.1 - 7.6e-116 387.1 0.0 8.7e-116 386.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CDO74032.1 - 3.6e-05 22.7 0.0 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein MMS22L_N PF14910.6 CDO74033.1 - 0.12 10.8 0.5 0.17 10.3 0.5 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal Sedlin_N PF04628.13 CDO74034.1 - 1.5e-33 115.7 0.1 1.7e-33 115.5 0.1 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CDO74034.1 - 2.2e-09 37.4 0.0 2.4e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Rhomboid PF01694.22 CDO74035.1 - 2.2e-22 79.7 10.7 2.6e-22 79.5 10.7 1.0 1 0 0 1 1 1 1 Rhomboid family Phage_holin_4_1 PF05105.12 CDO74035.1 - 0.087 13.0 0.1 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage holin family SNARE_assoc PF09335.11 CDO74037.1 - 1.4e-13 51.4 6.9 1.4e-13 51.4 6.9 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein ECF_trnsprt PF12822.7 CDO74037.1 - 1.1 9.3 12.0 2.7 8.1 12.0 1.7 1 1 0 1 1 1 0 ECF transporter, substrate-specific component HrpB7 PF09486.10 CDO74038.1 - 0.00025 21.5 1.7 0.0004 20.8 1.7 1.2 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Spore_III_AB PF09548.10 CDO74038.1 - 0.0024 18.0 0.0 0.0032 17.6 0.0 1.2 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) TPR_21 PF09976.9 CDO74038.1 - 0.0075 16.0 0.1 0.0092 15.7 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain DivIC PF04977.15 CDO74038.1 - 0.0084 15.9 0.6 0.011 15.5 0.6 1.1 1 0 0 1 1 1 1 Septum formation initiator DUF2076 PF09849.9 CDO74038.1 - 0.013 15.6 1.1 0.016 15.2 1.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PEX11 PF05648.14 CDO74039.1 - 4.7e-13 49.1 2.6 6e-12 45.5 1.6 2.7 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PPR_2 PF13041.6 CDO74040.1 - 4.4e-05 23.6 0.0 0.96 9.7 0.0 4.0 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 CDO74040.1 - 0.13 12.6 0.1 63 4.2 0.0 3.3 3 0 0 3 3 3 0 PPR repeat PPR_3 PF13812.6 CDO74040.1 - 0.14 12.2 0.0 4.4 7.5 0.0 2.9 2 0 0 2 2 2 0 Pentatricopeptide repeat domain CLASP_N PF12348.8 CDO74043.1 - 6.4e-72 241.8 0.0 8.2e-65 218.5 0.0 4.0 3 1 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 CDO74043.1 - 1.7e-07 30.9 0.5 0.59 10.5 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 CDO74043.1 - 0.0092 16.0 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CDO74043.1 - 0.32 11.5 5.5 1.4 9.5 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat HEAT_2 PF13646.6 CDO74043.1 - 2.1 8.8 9.1 1.8 9.0 0.0 4.8 5 1 0 5 5 5 0 HEAT repeats HSF_DNA-bind PF00447.17 CDO74044.1 - 4.4e-18 65.7 0.0 8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase PF00069.25 CDO74045.1 - 1.2e-73 247.7 0.0 1.6e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO74045.1 - 8.1e-31 107.2 0.1 3.8e-22 78.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDO74045.1 - 2.3e-09 37.0 0.3 0.00011 21.6 0.1 2.9 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CDO74045.1 - 0.00037 19.4 0.2 0.0014 17.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CDO74045.1 - 0.023 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 CDO74046.1 - 8e-28 97.4 18.4 3.4e-13 49.3 13.9 4.0 3 2 1 4 4 4 3 Major Facilitator Superfamily PUCC PF03209.15 CDO74046.1 - 0.001 18.1 3.0 0.001 18.1 3.0 2.2 2 1 1 3 3 3 1 PUCC protein MFS_1_like PF12832.7 CDO74046.1 - 1.3 7.8 10.2 0.048 12.5 0.7 2.8 3 0 0 3 3 3 0 MFS_1 like family COA2 PF17051.5 CDO74047.1 - 8.7e-07 28.9 0.0 9.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Ribosomal_S14 PF00253.21 CDO74048.1 - 1.3e-21 76.1 0.1 1.8e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF3425 PF11905.8 CDO74049.1 - 1.8e-13 50.6 0.2 1.1e-12 48.0 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) DUF4187 PF13821.6 CDO74052.1 - 2.2e-24 85.0 2.2 3.6e-24 84.3 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Bgal_small_N PF02929.17 CDO74052.1 - 0.074 12.7 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Beta galactosidase small chain RRM_1 PF00076.22 CDO74053.1 - 1.1e-29 102.0 0.1 3.8e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDO74053.1 - 0.035 13.7 0.0 3 7.5 0.0 2.4 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_cc PF11790.8 CDO74054.1 - 1.1e-57 195.4 0.1 1.7e-57 194.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core KorB PF08535.10 CDO74054.1 - 0.041 13.9 0.0 13 5.9 0.0 2.4 2 0 0 2 2 2 0 KorB domain Ribosomal_L11 PF00298.19 CDO74056.1 - 8.5e-30 103.1 0.4 1.2e-29 102.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 CDO74056.1 - 6.7e-28 96.3 0.1 1.2e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Peptidase_M28 PF04389.17 CDO74057.1 - 6e-20 71.8 0.0 1.4e-19 70.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CDO74057.1 - 0.0019 18.0 0.0 0.0035 17.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 CDO74058.1 - 4.7e-05 24.1 0.2 0.17 12.8 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Tnp_DNA_bind PF14706.6 CDO74058.1 - 0.08 12.8 1.4 46 4.0 0.0 3.5 3 0 0 3 3 3 0 Transposase DNA-binding WD40 PF00400.32 CDO74059.1 - 0.068 14.1 0.1 10 7.2 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF1912 PF08930.10 CDO74060.1 - 0.01 16.0 0.2 0.033 14.4 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1912) DFRP_C PF16543.5 CDO74060.1 - 0.022 15.2 2.5 0.038 14.5 2.5 1.5 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Wzy_C_2 PF11846.8 CDO74060.1 - 0.048 13.6 0.2 0.061 13.2 0.2 1.2 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal C2 PF00168.30 CDO74061.1 - 2.4e-14 53.5 0.0 6.3e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain Glyco_hydro_125 PF06824.11 CDO74062.1 - 6.8e-134 446.9 0.2 8.4e-134 446.6 0.2 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DUF1640 PF07798.11 CDO74064.1 - 1.4e-38 132.6 5.1 1.9e-38 132.3 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Macoilin PF09726.9 CDO74064.1 - 0.021 13.4 0.0 0.022 13.3 0.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF3584 PF12128.8 CDO74064.1 - 0.033 11.7 4.4 0.043 11.3 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.8 CDO74064.1 - 0.1 12.7 5.5 0.17 11.9 5.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding NAM-associated PF14303.6 CDO74064.1 - 0.23 12.2 1.2 1.5 9.5 1.2 2.0 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4404 PF14357.6 CDO74064.1 - 0.24 12.1 4.7 0.82 10.3 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Fzo_mitofusin PF04799.13 CDO74064.1 - 0.25 10.9 2.4 0.59 9.7 0.9 2.0 1 1 1 2 2 2 0 fzo-like conserved region PIN_8 PF18476.1 CDO74064.1 - 0.28 11.0 2.6 0.4 10.5 2.6 1.1 1 0 0 1 1 1 0 PIN like domain Mago-bind PF09282.10 CDO74065.1 - 1.3e-14 53.8 1.5 3.3e-14 52.4 1.5 1.7 1 0 0 1 1 1 1 Mago binding FAM176 PF14851.6 CDO74065.1 - 7.5 6.2 6.4 12 5.5 6.4 1.3 1 0 0 1 1 1 0 FAM176 family ATP_bind_1 PF03029.17 CDO74066.1 - 2.4e-63 214.1 0.0 9.7e-57 192.5 0.0 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CDO74066.1 - 0.00033 21.1 0.1 0.0024 18.3 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 CDO74066.1 - 0.00061 18.9 0.0 0.0021 17.2 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein ArsA_ATPase PF02374.15 CDO74066.1 - 0.0047 16.1 0.0 0.0069 15.6 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_33 PF13671.6 CDO74066.1 - 0.0075 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CDO74066.1 - 0.0087 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CDO74066.1 - 0.012 15.8 0.0 0.056 13.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDO74066.1 - 0.013 16.1 0.0 0.028 15.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CDO74066.1 - 0.014 15.4 0.1 0.15 12.2 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.23 CDO74066.1 - 0.017 15.2 0.0 0.019 15.0 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 CDO74066.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CLP1_P PF16575.5 CDO74066.1 - 0.019 14.8 0.0 0.13 12.0 0.0 2.2 2 1 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF463 PF04317.12 CDO74066.1 - 0.027 13.4 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 RNA_helicase PF00910.22 CDO74066.1 - 0.031 14.7 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 CDO74066.1 - 0.039 13.7 0.1 0.066 12.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CDO74066.1 - 0.058 13.3 0.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_10 PF12846.7 CDO74066.1 - 0.059 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.26 CDO74066.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CDO74066.1 - 0.071 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 CDO74066.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CDO74066.1 - 0.077 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CDO74066.1 - 0.094 12.6 0.2 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA_31 PF13614.6 CDO74066.1 - 0.12 12.3 0.1 5.4 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CDO74066.1 - 0.13 12.2 0.0 0.46 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CDO74066.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Septin MeaB PF03308.16 CDO74066.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 CDO74066.1 - 0.14 12.1 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 CDO74066.1 - 0.2 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 CDO74066.1 - 0.21 10.8 0.0 0.32 10.2 0.0 1.3 2 0 0 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.20 CDO74066.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Dynamin_N PF00350.23 CDO74067.1 - 6.3e-10 39.4 3.5 7.4e-09 35.9 0.0 3.6 3 1 0 3 3 3 1 Dynamin family EzrA PF06160.12 CDO74067.1 - 2.9 6.0 13.9 1.7 6.7 4.1 2.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Mlh1_C PF16413.5 CDO74067.1 - 4.9 6.4 7.1 1 8.7 0.3 2.7 3 0 0 3 3 3 0 DNA mismatch repair protein Mlh1 C-terminus MFS_1 PF07690.16 CDO74069.1 - 1.1e-15 57.5 8.2 1.1e-15 57.5 8.2 2.6 2 1 1 3 3 3 1 Major Facilitator Superfamily MFS_1 PF07690.16 CDO74070.1 - 2.6e-30 105.6 23.2 3.6e-30 105.1 23.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OSTbeta PF15048.6 CDO74070.1 - 0.04 14.1 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Thiolase_N PF00108.23 CDO74071.1 - 5.6e-86 288.1 0.6 8.5e-86 287.5 0.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CDO74071.1 - 1.9e-38 130.9 0.7 1.9e-38 130.9 0.7 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CDO74071.1 - 4.5e-05 23.2 4.7 0.00069 19.3 1.5 2.8 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CDO74071.1 - 0.07 13.0 4.5 0.12 12.2 0.4 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 2-Hacid_dh PF00389.30 CDO74071.1 - 0.084 12.5 0.1 0.44 10.2 0.0 2.0 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACP_syn_III_C PF08541.10 CDO74071.1 - 0.097 12.9 0.0 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ribosomal_S3Ae PF01015.18 CDO74072.1 - 1.4e-93 312.1 2.2 1.7e-93 311.8 2.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family LMP PF04778.12 CDO74072.1 - 0.015 15.2 0.3 0.026 14.4 0.3 1.5 1 0 0 1 1 1 0 LMP repeated region Pribosyltran PF00156.27 CDO74073.1 - 3.4e-14 52.7 0.1 4.3e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_hydro_47 PF01532.20 CDO74074.1 - 3.5e-77 260.3 0.0 4.5e-55 187.4 0.0 2.1 1 1 0 2 2 2 2 Glycosyl hydrolase family 47 PA PF02225.22 CDO74074.1 - 0.00075 19.5 0.1 0.0017 18.3 0.1 1.6 1 0 0 1 1 1 1 PA domain Auto_anti-p27 PF06677.12 CDO74075.1 - 1.5e-26 92.3 4.1 1.9e-13 50.3 0.3 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DpnI PF06044.12 CDO74075.1 - 0.054 13.1 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Dam-replacing family ADK_lid PF05191.14 CDO74075.1 - 0.1 12.6 0.6 7.8 6.6 0.2 3.3 3 1 0 3 3 3 0 Adenylate kinase, active site lid zf-ribbon_3 PF13248.6 CDO74075.1 - 0.17 11.3 5.8 30 4.2 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain MAGUK_N_PEST PF10608.9 CDO74076.1 - 0.36 11.3 4.1 0.11 13.0 0.7 1.8 2 0 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK HemY_N PF07219.13 CDO74077.1 - 8.1 6.7 5.9 14 5.9 5.9 1.4 1 0 0 1 1 1 0 HemY protein N-terminus DUF4268 PF14088.6 CDO74078.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) PCRF PF03462.18 CDO74079.1 - 2.2e-55 187.5 0.9 9.1e-55 185.5 0.0 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CDO74079.1 - 6.4e-35 119.6 3.1 1.4e-34 118.5 3.1 1.5 1 0 0 1 1 1 1 RF-1 domain Ribonuclease_3 PF00636.26 CDO74080.1 - 2.8e-44 150.0 0.0 2e-21 76.6 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CDO74080.1 - 5.7e-28 97.6 0.1 4.2e-12 46.3 0.0 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like Dicer_dimer PF03368.14 CDO74080.1 - 2.4e-08 34.0 0.0 5.3e-07 29.7 0.0 2.9 2 0 0 2 2 2 1 Dicer dimerisation domain PAZ PF02170.22 CDO74080.1 - 0.00024 20.9 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 PAZ domain COX7C PF02935.16 CDO74081.1 - 3.9e-15 55.8 0.9 4.3e-15 55.7 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc MFS_1 PF07690.16 CDO74082.1 - 2.6e-40 138.4 31.3 2.4e-39 135.3 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO74082.1 - 1.7e-09 37.1 6.1 1.7e-09 37.1 6.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Ank_2 PF12796.7 CDO74083.1 - 7.2e-18 65.0 0.2 7.5e-09 36.1 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDO74083.1 - 7.9e-17 61.4 0.2 4.2e-10 40.0 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CDO74083.1 - 9.5e-15 54.3 0.9 3e-06 27.4 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CDO74083.1 - 3.4e-12 46.3 0.1 0.00016 21.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDO74083.1 - 4.3e-12 45.1 0.2 0.0002 21.5 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.13 CDO74083.1 - 0.0037 17.1 0.0 0.019 14.8 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain DSPn PF14671.6 CDO74084.1 - 3.1e-41 141.1 0.0 6.1e-40 136.9 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CDO74084.1 - 3.6e-14 52.7 0.0 7.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDO74084.1 - 0.00014 21.5 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDO74084.1 - 0.001 19.2 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Pheromone PF08015.11 CDO74084.1 - 0.037 15.1 4.3 2.7 9.1 0.1 3.3 1 1 1 2 2 2 0 Fungal mating-type pheromone URO-D PF01208.17 CDO74085.1 - 9.3e-126 419.6 0.0 1.1e-125 419.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) COMPASS-Shg1 PF05205.12 CDO74086.1 - 8.2e-12 45.7 0.0 1.2e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 SPK PF04435.18 CDO74086.1 - 0.061 13.7 0.1 0.17 12.3 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF545) DUF3165 PF11364.8 CDO74087.1 - 1.8 9.0 7.6 1.6 9.1 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3165) Ribosomal_L12 PF00542.19 CDO74088.1 - 2.8e-21 75.6 10.3 5.1e-21 74.8 4.1 2.4 2 1 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CDO74088.1 - 6.8e-13 48.1 12.4 7.6e-13 47.9 4.4 2.7 3 0 0 3 3 3 2 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 CDO74088.1 - 0.022 15.3 5.3 0.022 15.3 5.3 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein HrpB_C PF08482.10 CDO74088.1 - 0.078 13.4 0.1 0.14 12.6 0.1 1.4 1 1 0 1 1 1 0 ATP-dependent helicase C-terminal Coatomer_E PF04733.14 CDO74088.1 - 0.12 11.8 0.6 0.15 11.4 0.6 1.1 1 0 0 1 1 1 0 Coatomer epsilon subunit Disulph_isomer PF06491.11 CDO74088.1 - 0.13 12.4 0.7 0.19 11.9 0.7 1.3 1 0 0 1 1 1 0 Disulphide isomerase Not3 PF04065.15 CDO74089.1 - 2.1e-90 302.2 22.2 2.1e-90 302.2 22.2 1.5 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CDO74089.1 - 4.3e-46 156.2 7.5 1.9e-45 154.1 7.5 2.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 CDO74089.1 - 0.0012 19.1 3.9 0.0052 17.1 3.9 2.1 1 0 0 1 1 1 1 Syntaxin-like protein DHO_dh PF01180.21 CDO74089.1 - 0.12 11.6 0.6 0.2 10.9 0.6 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Exonuc_VII_S PF02609.16 CDO74089.1 - 0.92 9.6 4.8 28 4.9 0.1 3.5 3 0 0 3 3 3 0 Exonuclease VII small subunit DUF4407 PF14362.6 CDO74089.1 - 4.4 6.6 12.5 9 5.5 12.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 CDO74089.1 - 9.1 7.0 11.8 4 8.2 2.4 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) SH3_1 PF00018.28 CDO74090.1 - 5.2e-26 90.0 0.0 1.1e-11 44.1 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CDO74090.1 - 1e-14 53.9 0.0 3.2e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 CDO74090.1 - 3e-14 52.6 0.0 6.2e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 CDO74090.1 - 4.6e-09 36.2 0.1 1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 PX domain DUF515 PF04415.12 CDO74090.1 - 2.8 6.2 4.2 5.2 5.3 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) GAS2 PF02187.17 CDO74091.1 - 1.8e-12 47.1 0.0 5.4e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Caldesmon PF02029.15 CDO74091.1 - 0.0045 15.8 34.9 0.014 14.2 34.9 1.8 1 0 0 1 1 1 1 Caldesmon CAF-1_p150 PF11600.8 CDO74091.1 - 1.4 8.6 42.9 4.9 6.8 42.9 2.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HIP1_clath_bdg PF16515.5 CDO74092.1 - 0.00019 22.0 9.2 0.00019 22.0 9.2 1.7 2 0 0 2 2 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 CDO74092.1 - 0.0038 16.9 1.0 0.0062 16.2 1.0 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF4472 PF14739.6 CDO74092.1 - 0.0058 17.3 6.2 0.012 16.4 6.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) ADIP PF11559.8 CDO74092.1 - 0.008 16.3 9.2 0.017 15.2 9.2 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding HALZ PF02183.18 CDO74092.1 - 0.0082 16.3 2.7 0.022 14.9 2.7 1.8 1 0 0 1 1 1 1 Homeobox associated leucine zipper YabA PF06156.13 CDO74092.1 - 0.019 15.6 1.3 0.034 14.8 0.3 1.9 1 1 1 2 2 2 0 Initiation control protein YabA PspA_IM30 PF04012.12 CDO74092.1 - 0.023 14.3 7.7 0.039 13.5 7.7 1.3 1 0 0 1 1 1 0 PspA/IM30 family Fez1 PF06818.15 CDO74092.1 - 0.024 15.1 2.8 0.042 14.3 2.8 1.5 1 0 0 1 1 1 0 Fez1 Mod_r PF07200.13 CDO74092.1 - 0.028 14.5 7.8 0.047 13.8 7.8 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Tropomyosin_1 PF12718.7 CDO74092.1 - 0.048 13.8 8.1 0.08 13.1 8.1 1.3 1 0 0 1 1 1 0 Tropomyosin like SesA PF17107.5 CDO74092.1 - 0.051 13.8 0.6 0.1 12.8 0.6 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TMF_TATA_bd PF12325.8 CDO74092.1 - 0.065 13.5 7.5 0.12 12.6 7.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Syntaxin_2 PF14523.6 CDO74092.1 - 0.077 13.4 7.2 0.14 12.6 7.2 1.4 1 0 0 1 1 1 0 Syntaxin-like protein TolA_bind_tri PF16331.5 CDO74092.1 - 0.078 13.1 0.7 0.078 13.1 0.7 2.6 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF4407 PF14362.6 CDO74092.1 - 0.091 12.1 5.2 0.035 13.5 2.8 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HOOK PF05622.12 CDO74092.1 - 0.17 10.0 8.9 0.23 9.6 8.9 1.1 1 0 0 1 1 1 0 HOOK protein YkyA PF10368.9 CDO74092.1 - 0.19 11.4 9.2 0.28 10.8 9.2 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF1664 PF07889.12 CDO74092.1 - 0.26 11.3 3.1 0.41 10.7 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 CDO74092.1 - 0.32 10.7 10.5 0.55 9.9 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 CDO74092.1 - 0.38 9.6 9.7 0.54 9.1 9.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 CDO74092.1 - 0.38 9.8 4.2 0.54 9.3 4.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-Q PF13094.6 CDO74092.1 - 0.39 10.9 10.2 0.64 10.2 10.2 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit M PF02370.16 CDO74092.1 - 0.5 11.1 7.5 0.62 10.8 1.7 3.1 2 1 1 3 3 2 0 M protein repeat DUF812 PF05667.11 CDO74092.1 - 0.65 8.8 6.7 1 8.1 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 CDO74092.1 - 0.97 8.7 11.0 1.4 8.2 11.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 CDO74092.1 - 1.1 9.5 4.1 2 8.6 4.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 CDO74092.1 - 1.4 9.5 10.0 2.5 8.6 10.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 CDO74092.1 - 2.5 8.3 10.2 3.9 7.7 10.2 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Ax_dynein_light PF10211.9 CDO74092.1 - 2.6 8.0 9.7 4.2 7.3 9.7 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain DUF724 PF05266.14 CDO74092.1 - 2.6 7.8 6.4 4.6 7.0 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Nup88 PF10168.9 CDO74092.1 - 3.6 5.3 5.6 5 4.8 5.6 1.1 1 0 0 1 1 1 0 Nuclear pore component BST2 PF16716.5 CDO74092.1 - 4.1 8.0 8.5 4.8 7.8 1.0 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 PRKG1_interact PF15898.5 CDO74092.1 - 4.4 8.3 11.4 3.4 8.6 4.0 2.5 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain DUF3450 PF11932.8 CDO74092.1 - 5.7 6.2 7.6 9.4 5.4 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) R3H PF01424.22 CDO74094.1 - 8.2e-14 51.3 0.2 1.3e-13 50.7 0.2 1.3 1 0 0 1 1 1 1 R3H domain DUF3123 PF11321.8 CDO74094.1 - 0.016 15.8 0.7 0.016 15.8 0.7 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3123) Aconitase PF00330.20 CDO74095.1 - 2.4e-163 544.5 0.0 2.8e-163 544.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDO74095.1 - 3.4e-33 114.8 0.0 5.8e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain PepSY PF03413.19 CDO74095.1 - 0.1 13.2 0.0 0.28 11.8 0.0 1.7 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Methyltransf_16 PF10294.9 CDO74096.1 - 8.9e-46 155.8 0.0 1.1e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CDO74096.1 - 0.0019 17.7 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CDO74096.1 - 0.0068 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CDO74096.1 - 0.022 15.4 0.0 0.043 14.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain KH_8 PF17903.1 CDO74099.1 - 1.6e-33 114.6 0.1 3.8e-32 110.2 0.0 2.4 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 CDO74099.1 - 0.0017 18.2 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 CDO74099.1 - 0.037 13.9 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 KH domain SRP-alpha_N PF04086.13 CDO74099.1 - 8.7 6.2 25.9 11 5.8 25.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NCBP3 PF10309.9 CDO74100.1 - 9.9e-14 50.9 0.0 1.6e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 CDO74100.1 - 3.2e-05 24.4 20.0 0.00038 21.0 6.7 3.2 3 1 0 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 BolA PF01722.18 CDO74101.1 - 7.6e-14 51.8 0.0 2.6e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein COX15-CtaA PF02628.15 CDO74102.1 - 2.2e-109 365.4 10.2 3e-109 365.0 10.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Proteasome PF00227.26 CDO74103.1 - 3.4e-53 180.0 0.0 4.1e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDO74103.1 - 6.4e-13 48.1 1.7 1.2e-12 47.3 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribosomal_L12_N PF16320.5 CDO74103.1 - 0.72 9.6 4.5 1.7 8.4 4.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain Aldedh PF00171.22 CDO74105.1 - 8.3e-175 581.7 0.1 1e-174 581.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zn_clus PF00172.18 CDO74106.1 - 4.9e-10 39.4 9.2 6.7e-10 38.9 9.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 CDO74107.1 - 6e-60 202.0 0.0 9.1e-60 201.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDO74107.1 - 2.9e-08 33.2 0.6 7.4e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AhpC-TSA PF00578.21 CDO74108.1 - 2.5e-32 111.4 0.0 3.2e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDO74108.1 - 1.1e-12 47.9 0.0 1.6e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CDO74108.1 - 2.9e-08 33.4 0.3 5.5e-08 32.5 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 CDO74108.1 - 0.16 12.1 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme sCache_3_2 PF17203.4 CDO74108.1 - 0.23 11.6 0.1 4 7.6 0.0 2.0 1 1 1 2 2 2 0 Single cache domain 3 Ssu72 PF04722.13 CDO74109.1 - 1.7e-85 285.4 0.0 2.2e-85 285.0 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein PRCC PF10253.9 CDO74109.1 - 0.018 15.8 0.3 0.019 15.8 0.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4030 PF13222.6 CDO74109.1 - 0.17 12.1 0.9 1.7 8.8 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4030) adh_short PF00106.25 CDO74110.1 - 3.3e-22 78.9 0.0 7.2e-17 61.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO74110.1 - 8.5e-12 45.1 0.1 9.8e-09 35.1 0.0 2.6 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO74110.1 - 0.00049 20.1 0.1 0.00082 19.3 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CDO74110.1 - 0.024 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 CDO74110.1 - 0.051 13.0 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_trans_4_2 PF13477.6 CDO74110.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like adh_short PF00106.25 CDO74111.1 - 9.3e-43 146.0 0.2 1e-19 70.8 0.0 4.2 2 2 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO74111.1 - 1.9e-25 89.8 0.4 1.2e-10 41.4 0.1 4.2 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO74111.1 - 7.3e-13 48.8 2.5 4.7e-06 26.6 0.3 2.3 2 0 0 2 2 2 2 KR domain MoCF_biosynth PF00994.24 CDO74111.1 - 0.00061 19.5 0.1 0.77 9.4 0.0 2.8 3 0 0 3 3 3 2 Probable molybdopterin binding domain Epimerase PF01370.21 CDO74111.1 - 0.0031 17.0 0.2 0.17 11.4 0.1 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Tau95 PF09734.9 CDO74112.1 - 1.2e-41 142.8 1.2 4e-41 141.1 0.6 2.2 3 0 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CDO74112.1 - 4.1e-29 101.3 0.0 1.7e-28 99.4 0.0 2.1 2 0 0 2 2 2 1 Tau95 Triple barrel domain Pkr1 PF08636.10 CDO74113.1 - 1e-19 70.4 6.3 1.3e-19 70.1 6.3 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Tmemb_9 PF05434.11 CDO74113.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 TMEM9 Sld5 PF05916.11 CDO74114.1 - 5.9e-07 29.9 0.0 8.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sigma70_r1_1 PF03979.14 CDO74115.1 - 0.028 14.5 0.2 0.028 14.5 0.2 2.3 2 1 1 3 3 3 0 Sigma-70 factor, region 1.1 Hydrolase_6 PF13344.6 CDO74115.1 - 0.051 13.7 0.1 0.28 11.3 0.1 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase UPF0449 PF15136.6 CDO74115.1 - 0.07 13.6 0.7 0.14 12.6 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Pkinase PF00069.25 CDO74116.1 - 1.4e-75 254.1 0.5 4.9e-75 252.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO74116.1 - 8e-37 126.9 0.2 1.9e-36 125.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO74116.1 - 0.0016 17.3 3.1 0.0056 15.5 3.1 1.8 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO74116.1 - 0.0058 16.6 6.9 0.29 11.0 0.0 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Ndc1_Nup PF09531.10 CDO74116.1 - 0.21 10.2 1.4 0.32 9.7 1.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2058 PF09831.9 CDO74116.1 - 0.34 11.0 16.6 0.55 10.4 16.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) EFTUD2 PF16004.5 CDO74116.1 - 0.43 11.2 11.7 0.79 10.3 11.7 1.3 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Kinase-like PF14531.6 CDO74116.1 - 0.52 9.6 11.6 1.1 8.5 0.0 3.5 4 0 0 4 4 3 0 Kinase-like TERB2 PF15101.6 CDO74116.1 - 0.9 9.6 9.7 1.7 8.7 9.7 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TMEM51 PF15345.6 CDO74116.1 - 1 9.1 10.2 1.6 8.6 10.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Presenilin PF01080.17 CDO74116.1 - 2.5 6.8 9.6 3.4 6.3 9.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 CDO74116.1 - 3.1 7.1 11.2 4.4 6.6 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CDO74116.1 - 3.9 7.4 18.4 0.67 9.9 14.9 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MGTL PF17059.5 CDO74116.1 - 4 7.4 7.0 8.4 6.4 7.0 1.5 1 0 0 1 1 1 0 MgtA leader peptide DDRGK PF09756.9 CDO74116.1 - 4.9 6.7 18.9 7.8 6.0 18.9 1.2 1 0 0 1 1 1 0 DDRGK domain Baculo_PP31 PF05311.11 CDO74116.1 - 7.5 6.0 10.6 14 5.0 10.6 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Spt20 PF12090.8 CDO74116.1 - 8.5 5.9 22.5 13 5.3 22.5 1.2 1 0 0 1 1 1 0 Spt20 family CCDC53 PF10152.9 CDO74116.1 - 10 6.6 10.6 49 4.3 10.4 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex EAF PF09816.9 CDO74118.1 - 9.5e-21 74.1 0.0 2e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Ferritin_2 PF13668.6 CDO74120.1 - 3e-35 121.4 1.5 5.8e-35 120.5 1.5 1.4 1 0 0 1 1 1 1 Ferritin-like domain FTR PF01913.18 CDO74120.1 - 0.73 9.8 0.0 0.73 9.8 0.0 2.2 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase SWI-SNF_Ssr4 PF08549.10 CDO74120.1 - 2.9 6.4 9.1 4.3 5.9 9.1 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Peptidase_S10 PF00450.22 CDO74121.1 - 4e-77 260.4 0.0 2.7e-76 257.6 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Nop PF01798.18 CDO74122.1 - 1.4e-77 260.3 0.1 1.4e-77 260.3 0.1 2.9 3 0 0 3 3 3 2 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CDO74122.1 - 3.5e-21 75.4 0.3 3.5e-21 75.4 0.3 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain CDC27 PF09507.10 CDO74122.1 - 5.6 6.2 35.4 7.7 5.8 35.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ATP_bind_3 PF01171.20 CDO74123.1 - 6.3e-18 65.2 0.0 9.6e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CDO74123.1 - 1.8e-16 59.3 3.8 1.8e-16 59.3 3.8 3.8 4 0 0 4 4 4 1 Zinc-ribbon RecR PF02132.15 CDO74123.1 - 0.01 15.4 1.7 0.01 15.4 1.7 3.7 4 0 0 4 4 4 0 RecR protein CTU2 PF10288.9 CDO74123.1 - 0.062 13.6 1.0 0.46 10.8 0.0 2.5 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 CpXC PF14353.6 CDO74123.1 - 0.084 12.9 1.0 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 CpXC protein TF_Zn_Ribbon PF08271.12 CDO74123.1 - 0.45 10.1 10.6 0.83 9.2 0.1 3.6 3 1 1 4 4 4 0 TFIIB zinc-binding DUF2616 PF11077.8 CDO74123.1 - 5.6 6.6 8.7 2 8.1 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) PUF PF00806.19 CDO74124.1 - 1.3e-19 68.7 0.0 0.00017 21.1 0.0 7.9 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat Bystin PF05291.11 CDO74125.1 - 1.1e-124 415.5 0.0 1.4e-124 415.1 0.0 1.1 1 0 0 1 1 1 1 Bystin CM_1 PF07736.11 CDO74125.1 - 0.032 14.6 0.1 7.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Chorismate mutase type I DNA_pol_phi PF04931.13 CDO74125.1 - 0.57 8.2 10.5 0.78 7.8 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi GDP_Man_Dehyd PF16363.5 CDO74126.1 - 2.1e-61 208.2 0.0 2.6e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDO74126.1 - 7.5e-45 153.3 0.0 1.1e-44 152.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO74126.1 - 5.9e-11 41.9 0.0 8.8e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CDO74126.1 - 2.3e-06 27.0 0.1 0.02 14.1 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 CDO74126.1 - 1e-05 24.8 0.0 3.1e-05 23.2 0.0 1.8 2 1 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDO74126.1 - 0.00039 19.6 0.1 0.029 13.5 0.1 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Abhydrolase_4 PF08386.10 CDO74127.1 - 0.0017 18.4 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein RGS PF00615.19 CDO74129.1 - 7.5e-40 135.9 0.3 2.4e-38 131.0 0.5 2.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 CDO74129.1 - 3.2e-06 27.1 0.1 0.38 10.8 0.0 3.6 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cyt-b5 PF00173.28 CDO74130.1 - 5.8e-11 42.4 0.2 9.2e-11 41.7 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nup160 PF11715.8 CDO74132.1 - 2.3e-20 72.8 0.0 1.2e-16 60.5 0.0 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 TPR_4 PF07721.14 CDO74132.1 - 0.017 15.7 0.2 0.1 13.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDO74132.1 - 0.044 14.3 0.1 0.27 11.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDO74132.1 - 0.054 13.5 1.4 1.3 9.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDO74132.1 - 0.18 12.5 1.8 1 10.0 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat B12D PF06522.11 CDO74133.1 - 1.2e-15 57.0 0.2 1.6e-15 56.6 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aldo_ket_red PF00248.21 CDO74134.1 - 8.2e-39 133.5 0.0 1e-38 133.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DALR_1 PF05746.15 CDO74134.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 DALR anticodon binding domain dCMP_cyt_deam_1 PF00383.23 CDO74135.1 - 7.7e-05 22.5 1.4 0.00048 20.0 1.4 2.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDO74135.1 - 0.00043 20.1 0.5 0.0014 18.3 0.0 2.0 2 1 0 2 2 2 1 MafB19-like deaminase Plectin PF00681.20 CDO74135.1 - 0.039 13.8 0.1 0.2 11.5 0.1 2.1 2 0 0 2 2 2 0 Plectin repeat ATG16 PF08614.11 CDO74136.1 - 4.9e-05 23.7 10.6 4.9e-05 23.7 10.6 2.7 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Fez1 PF06818.15 CDO74136.1 - 0.015 15.7 17.6 0.039 14.4 17.6 1.6 1 0 0 1 1 1 0 Fez1 DUF4407 PF14362.6 CDO74136.1 - 0.034 13.5 10.3 0.056 12.8 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 CDO74136.1 - 0.036 13.4 19.4 0.57 9.5 0.8 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HOOK PF05622.12 CDO74136.1 - 0.04 12.1 15.0 0.062 11.5 15.0 1.2 1 0 0 1 1 1 0 HOOK protein DUF3450 PF11932.8 CDO74136.1 - 0.056 12.7 15.3 0.16 11.2 10.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HMMR_C PF15908.5 CDO74136.1 - 0.13 12.5 11.2 0.82 9.9 11.2 2.0 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Golgin_A5 PF09787.9 CDO74136.1 - 0.2 11.1 16.0 0.44 10.0 16.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 TLE_N PF03920.15 CDO74136.1 - 0.2 11.8 2.7 1.9 8.6 1.0 2.3 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Tmemb_cc2 PF10267.9 CDO74136.1 - 0.45 9.6 14.3 13 4.8 14.2 2.2 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Cnn_1N PF07989.11 CDO74136.1 - 0.48 10.6 0.0 0.48 10.6 0.0 3.3 2 1 0 2 2 1 0 Centrosomin N-terminal motif 1 ThylakoidFormat PF11264.8 CDO74136.1 - 0.72 9.5 5.0 3.3 7.3 0.1 2.4 2 0 0 2 2 2 0 Thylakoid formation protein V_ATPase_I PF01496.19 CDO74136.1 - 1.1 7.1 4.1 1.7 6.5 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 CDO74136.1 - 1.4 7.9 15.2 12 4.9 15.2 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 CDO74136.1 - 1.4 8.4 8.0 2.3 7.7 8.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Borrelia_P83 PF05262.11 CDO74136.1 - 1.5 7.2 13.7 2.3 6.6 13.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein ADIP PF11559.8 CDO74136.1 - 2.9 8.0 17.9 21 5.2 0.1 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4530 PF15039.6 CDO74136.1 - 4.9 7.3 10.5 6.3 7.0 3.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4530) CorA PF01544.18 CDO74136.1 - 4.9 6.4 4.8 5.7 6.2 3.9 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Leu_zip PF15294.6 CDO74136.1 - 5.7 6.4 14.3 7.2 6.0 10.8 2.1 1 1 1 2 2 2 0 Leucine zipper AAA_13 PF13166.6 CDO74136.1 - 7.7 5.0 12.3 37 2.8 12.3 1.7 1 1 0 1 1 1 0 AAA domain DivIC PF04977.15 CDO74136.1 - 9.3 6.1 21.5 2.1 8.2 2.8 3.9 2 1 1 3 3 3 0 Septum formation initiator T3SSipB PF16535.5 CDO74136.1 - 9.4 6.7 14.0 15 6.1 13.1 1.8 1 1 0 1 1 1 0 Type III cell invasion protein SipB DAD PF02109.16 CDO74138.1 - 4.6e-47 158.8 1.2 5.3e-47 158.6 1.2 1.0 1 0 0 1 1 1 1 DAD family Sod_Fe_C PF02777.18 CDO74139.1 - 1.9e-09 37.6 0.0 3.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain CD24 PF14984.6 CDO74139.1 - 1.3 9.3 7.4 49 4.2 6.0 2.4 2 0 0 2 2 2 0 CD24 protein Adap_comp_sub PF00928.21 CDO74140.1 - 1.8e-55 188.2 0.0 2.4e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family MMR_HSR1 PF01926.23 CDO74140.1 - 2.6e-17 62.9 0.0 7.9e-17 61.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase MnmE_helical PF12631.7 CDO74140.1 - 1.2e-08 35.4 0.0 2.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 MnmE helical domain Dynamin_N PF00350.23 CDO74140.1 - 2.7e-05 24.3 0.0 0.00039 20.5 0.0 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 CDO74140.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Clat_adaptor_s PF01217.20 CDO74140.1 - 0.0024 17.8 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA_28 PF13521.6 CDO74140.1 - 0.056 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CDO74140.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CDO74140.1 - 0.19 11.6 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase EF-hand_1 PF00036.32 CDO74141.1 - 3.1e-28 95.2 11.0 3.3e-08 32.5 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDO74141.1 - 4.5e-24 84.7 4.1 1.9e-13 50.7 1.1 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDO74141.1 - 3.3e-22 76.4 7.0 4.4e-05 23.1 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDO74141.1 - 1.3e-18 65.6 13.9 1e-05 24.8 0.6 4.6 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDO74141.1 - 2.4e-14 52.9 12.7 0.0002 21.2 0.6 4.3 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDO74141.1 - 4.8e-06 26.9 0.0 0.027 14.8 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CDO74141.1 - 3.1e-05 23.9 5.7 0.03 14.3 0.6 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CDO74141.1 - 0.0046 17.2 0.1 0.91 9.9 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain PMBR PF09373.10 CDO74141.1 - 0.096 12.9 0.0 4.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Pseudomurein-binding repeat Mt_ATP-synt_D PF05873.12 CDO74142.1 - 5.2e-15 55.6 1.0 6.2e-15 55.4 1.0 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) OmpH PF03938.14 CDO74142.1 - 0.00036 20.9 1.7 0.028 14.8 1.7 2.1 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) Prominin PF05478.11 CDO74142.1 - 0.0024 15.9 0.1 0.0026 15.8 0.1 1.0 1 0 0 1 1 1 1 Prominin GAS PF13851.6 CDO74142.1 - 0.035 13.5 1.5 0.05 13.0 1.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding RPW8 PF05659.11 CDO74142.1 - 0.043 13.5 0.6 0.22 11.2 0.5 1.9 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Cob_adeno_trans PF01923.18 CDO74142.1 - 0.044 13.9 1.0 0.086 13.0 0.3 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF2408 PF10303.9 CDO74142.1 - 0.046 14.3 0.7 0.069 13.7 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) NPV_P10 PF05531.12 CDO74142.1 - 0.33 11.4 3.0 1.3 9.5 1.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Hexokinase_2 PF03727.16 CDO74143.1 - 1.3e-76 257.2 0.0 4.8e-43 147.3 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 CDO74143.1 - 2.9e-69 233.0 0.0 4e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.12 CDO74143.1 - 0.034 14.2 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Fungal_trans PF04082.18 CDO74144.1 - 1.1e-09 37.7 0.0 1.1e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain TFIIA PF03153.13 CDO74144.1 - 4.8 7.1 19.0 9.8 6.0 19.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_16 PF13191.6 CDO74145.1 - 8.2e-06 26.3 0.0 3.5e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CDO74145.1 - 4.1e-05 23.6 0.1 0.00019 21.4 0.1 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CDO74145.1 - 0.13 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0052 PF01933.18 CDO74145.1 - 0.23 10.7 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 TPR_1 PF00515.28 CDO74146.1 - 4.9e-56 184.4 27.4 7.6e-10 38.2 0.9 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 CDO74146.1 - 1.5e-46 152.7 27.6 2.9e-08 33.2 0.4 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 CDO74146.1 - 2.2e-33 111.6 27.2 0.00019 21.4 0.2 9.7 10 0 0 10 10 9 7 Tetratricopeptide repeat STI1 PF17830.1 CDO74146.1 - 6.7e-33 112.4 14.0 1.3e-17 63.4 1.5 3.0 3 0 0 3 3 2 2 STI1 domain TPR_11 PF13414.6 CDO74146.1 - 7.2e-30 102.4 22.4 1.3e-10 40.8 0.4 7.9 5 2 3 8 8 8 5 TPR repeat TPR_12 PF13424.6 CDO74146.1 - 3.5e-24 84.9 15.8 4.1e-10 39.8 0.0 7.6 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 CDO74146.1 - 5.3e-24 84.5 12.2 1.3e-07 32.1 0.0 7.2 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDO74146.1 - 1.4e-23 83.2 14.8 2.2e-08 34.6 0.5 6.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 CDO74146.1 - 8.2e-23 79.1 9.9 0.00098 19.3 0.2 8.0 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 CDO74146.1 - 4.5e-22 76.4 6.4 0.0011 18.8 0.0 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 CDO74146.1 - 8.9e-22 75.9 12.7 0.0067 17.2 0.0 9.8 3 3 6 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 CDO74146.1 - 1.5e-16 60.3 3.9 9e-05 22.6 0.0 5.6 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 CDO74146.1 - 1.5e-12 47.3 22.8 0.61 10.8 0.1 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 CDO74146.1 - 1.5e-12 46.9 14.9 0.067 13.1 0.2 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_3 PF07720.12 CDO74146.1 - 1.8e-07 31.0 10.3 0.61 10.1 0.2 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO74146.1 - 5e-07 29.9 9.0 0.097 12.9 0.1 5.0 3 3 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 CDO74146.1 - 0.0016 18.9 14.9 0.58 10.6 0.5 5.4 3 3 2 5 5 5 1 Bacterial transcriptional activator domain NARP1 PF12569.8 CDO74146.1 - 0.0019 17.2 1.8 0.0019 17.2 1.8 4.2 3 3 2 5 5 4 1 NMDA receptor-regulated protein 1 XPC-binding PF09280.11 CDO74146.1 - 0.01 15.6 7.6 0.32 10.8 0.5 2.8 2 0 0 2 2 2 0 XPC-binding domain MAS20 PF02064.15 CDO74146.1 - 0.011 15.8 9.2 0.77 9.9 0.3 4.4 3 1 0 3 3 3 0 MAS20 protein import receptor SPO22 PF08631.10 CDO74146.1 - 0.012 15.1 5.3 6.6 6.1 0.1 4.8 4 1 1 5 5 5 0 Meiosis protein SPO22/ZIP4 like DUF4919 PF16266.5 CDO74146.1 - 0.02 14.9 3.6 1.3 8.9 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4919) Alkyl_sulf_dimr PF14863.6 CDO74146.1 - 0.044 14.2 9.7 5.2 7.5 0.3 4.3 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation TPR_21 PF09976.9 CDO74146.1 - 0.047 13.4 19.6 0.24 11.1 0.9 5.0 2 2 2 4 4 4 0 Tetratricopeptide repeat-like domain RPN7 PF10602.9 CDO74146.1 - 0.051 13.3 8.1 7.9 6.1 0.4 4.9 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TOM20_plant PF06552.12 CDO74146.1 - 0.082 12.6 9.5 6.1 6.6 0.1 5.0 3 2 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 VasL PF12486.8 CDO74146.1 - 0.13 12.1 1.6 0.17 11.7 0.2 1.9 2 0 0 2 2 1 0 Type VI secretion system, EvfB, or VasL Fis1_TPR_C PF14853.6 CDO74146.1 - 0.18 11.9 7.3 7.4 6.7 0.0 5.3 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 CDO74146.1 - 0.4 11.0 19.2 0.72 10.2 0.1 5.2 5 1 0 6 6 4 0 Tetratricopeptide repeat Sel1 PF08238.12 CDO74146.1 - 0.42 11.4 4.9 2.9 8.7 0.1 4.4 5 0 0 5 5 4 0 Sel1 repeat HHH_8 PF14716.6 CDO74146.1 - 0.9 9.9 7.5 29 5.1 0.1 4.4 4 0 0 4 4 4 0 Helix-hairpin-helix domain MIT PF04212.18 CDO74146.1 - 1.1 9.4 26.0 4.9 7.3 0.1 7.6 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain BNIP3 PF06553.12 CDO74146.1 - 1.6 8.4 4.3 3.5 7.3 4.3 1.5 1 0 0 1 1 1 0 BNIP3 TPM_phosphatase PF04536.14 CDO74146.1 - 3.1 8.0 5.6 13 6.0 0.1 3.4 4 0 0 4 4 3 0 TPM domain EphA2_TM PF14575.6 CDO74147.1 - 0.0099 16.7 0.0 0.014 16.3 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 CDO74147.1 - 0.032 14.1 0.3 0.05 13.5 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain DUF3318 PF11780.8 CDO74147.1 - 0.093 12.7 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Amnionless PF14828.6 CDO74148.1 - 0.077 11.8 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Amnionless p450 PF00067.22 CDO74150.1 - 9.3e-56 189.5 0.0 2.1e-55 188.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Aft1_HRA PF11786.8 CDO74152.1 - 6.6e-20 71.2 12.4 6.6e-20 71.2 12.4 3.4 3 0 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.21 CDO74152.1 - 2.2e-10 40.5 9.4 4e-10 39.6 9.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDO74152.1 - 1.1e-05 25.4 9.6 1.1e-05 25.4 9.6 1.9 2 0 0 2 2 2 1 Basic region leucine zipper MCC-bdg_PDZ PF10506.9 CDO74152.1 - 0.0056 16.7 0.3 0.01 15.8 0.3 1.4 1 0 0 1 1 1 1 PDZ domain of MCC-2 bdg protein for Usher syndrome HAUS-augmin3 PF14932.6 CDO74152.1 - 2.3 7.7 10.4 4 7.0 10.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Plavaka PF18759.1 CDO74153.1 - 7.6e-26 91.1 0.0 1.6e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase Trypan_PARP PF05887.11 CDO74154.1 - 0.014 15.4 9.2 0.014 15.4 9.2 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CCDC53 PF10152.9 CDO74154.1 - 8.7 6.8 14.3 8.8 6.7 0.3 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Aldo_ket_red PF00248.21 CDO74155.1 - 8.9e-48 163.0 0.0 1e-47 162.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L18 PF17135.4 CDO74156.1 - 1.6e-89 298.3 2.7 1.7e-89 298.2 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CDO74156.1 - 0.00054 20.6 0.0 0.00054 20.6 0.0 1.9 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RRM_1 PF00076.22 CDO74157.1 - 5.5e-17 61.4 0.0 9.9e-17 60.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDO74157.1 - 0.00023 20.8 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDO74157.1 - 0.003 17.4 0.0 0.0057 16.5 0.0 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif Aldo_ket_red PF00248.21 CDO74158.1 - 4.4e-39 134.4 0.0 5.4e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.8 CDO74158.1 - 0.028 14.4 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) Tti2 PF10521.9 CDO74159.1 - 1.7e-33 116.4 0.0 9.4e-33 113.9 0.0 1.8 2 0 0 2 2 2 1 Tti2 family POX PF07526.11 CDO74161.1 - 0.17 12.5 0.1 0.47 11.0 0.0 1.7 1 1 1 2 2 2 0 Associated with HOX Pkinase PF00069.25 CDO74162.1 - 5.4e-13 48.9 0.0 2.3e-11 43.6 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO74162.1 - 8e-07 28.6 0.0 4.2e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO74162.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Tti2 PF10521.9 CDO74163.1 - 1.7e-22 80.3 0.0 2.7e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Tti2 family Pkinase PF00069.25 CDO74165.1 - 0.00017 21.1 0.0 0.0066 15.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase PF00069.25 CDO74166.1 - 1.4e-06 27.9 0.0 3.1e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDO74166.1 - 0.011 15.1 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 CDO74166.1 - 0.035 13.4 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Cyclin PF08613.11 CDO74167.1 - 2.6e-43 148.2 0.3 2.6e-43 148.2 0.3 2.2 2 0 0 2 2 2 1 Cyclin PRKCSH-like PF12999.7 CDO74169.1 - 4.4e-50 169.9 0.3 9.4e-50 168.8 0.3 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CDO74169.1 - 3.3e-29 101.6 0.1 7.6e-29 100.4 0.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CDO74169.1 - 1.9e-09 38.4 0.2 6.4e-09 36.7 0.2 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF1043 PF06295.12 CDO74169.1 - 1 9.4 7.8 0.42 10.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Spc24 PF08286.11 CDO74169.1 - 1.2 9.5 6.1 10 6.4 0.1 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.8 CDO74169.1 - 2 8.5 19.3 1 9.4 5.2 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CAGE1 PF15066.6 CDO74169.1 - 4.4 5.9 16.2 0.35 9.5 8.4 2.1 2 0 0 2 2 2 0 Cancer-associated gene protein 1 family FlaC_arch PF05377.11 CDO74169.1 - 9 6.8 6.8 4.2 7.9 1.4 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ribosomal_L2_C PF03947.18 CDO74170.1 - 3.3e-47 159.8 3.2 5.2e-47 159.2 3.2 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CDO74170.1 - 1.7e-16 59.9 0.1 4.4e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain FGGY_C PF02782.16 CDO74171.1 - 4.1e-49 167.0 0.2 5.7e-49 166.5 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CDO74171.1 - 7.7e-22 78.0 0.0 2.6e-21 76.3 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 CDO74171.1 - 0.00018 21.1 1.6 0.45 10.0 0.1 2.9 1 1 1 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Geminin PF07412.12 CDO74171.1 - 0.0073 16.1 0.9 0.054 13.2 0.1 2.1 2 0 0 2 2 2 1 Geminin AnmK PF03702.14 CDO74171.1 - 0.017 14.3 0.2 0.017 14.3 0.2 1.8 2 0 0 2 2 2 0 Anhydro-N-acetylmuramic acid kinase Hexokinase_1 PF00349.21 CDO74171.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Hexokinase Cyclin PF08613.11 CDO74172.1 - 3e-06 27.7 0.1 4e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CDO74172.1 - 5.1e-06 26.2 0.1 7e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_S25 PF03297.15 CDO74173.1 - 1.8e-39 134.0 2.9 1.9e-39 133.9 2.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 CDO74173.1 - 0.0099 15.4 0.3 0.016 14.7 0.3 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AIPR PF10592.9 CDO74173.1 - 0.016 14.9 0.1 0.016 14.9 0.1 1.1 1 0 0 1 1 1 0 AIPR protein SSXT PF05030.12 CDO74174.1 - 8.8e-06 25.3 0.0 8.8e-06 25.3 0.0 2.9 3 0 0 3 3 3 1 SSXT protein (N-terminal region) SH3_9 PF14604.6 CDO74175.1 - 1.7e-07 31.0 0.1 2.8e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDO74175.1 - 0.00013 21.6 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDO74175.1 - 0.00056 19.5 0.1 0.00085 18.9 0.1 1.3 1 0 0 1 1 1 1 SH3 domain AKAP2_C PF15304.6 CDO74175.1 - 0.1 11.9 0.7 0.12 11.7 0.7 1.0 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Cyclin_N PF00134.23 CDO74176.1 - 3.1e-15 56.0 0.1 4.8e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CDO74176.1 - 6.8e-11 42.8 0.1 2.1e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin UAA PF08449.11 CDO74177.1 - 7e-11 41.9 0.0 4.7e-10 39.2 0.0 2.0 1 1 1 2 2 2 1 UAA transporter family Phage_holin_2_3 PF16080.5 CDO74177.1 - 0.13 12.0 4.7 3 7.7 0.5 3.0 3 1 0 3 3 3 0 Bacteriophage holin family HP1 Sex_peptide PF08138.11 CDO74177.1 - 0.16 12.2 1.7 0.58 10.3 0.2 2.5 3 0 0 3 3 3 0 Sex peptide (SP) family MIF4G_like_2 PF09090.11 CDO74178.1 - 9.7e-70 235.1 0.1 1.4e-69 234.6 0.1 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 CDO74178.1 - 4.2e-64 215.8 0.0 7.7e-64 215.0 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 CDO74178.1 - 0.0014 18.3 0.0 0.0059 16.3 0.0 2.0 2 0 0 2 2 2 1 MIF4G domain MHCassoc_trimer PF08831.10 CDO74178.1 - 2.1 8.4 5.5 7.4 6.7 5.0 2.2 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain PPR_2 PF13041.6 CDO74179.1 - 7.9e-05 22.8 0.0 0.38 11.0 0.0 4.3 4 0 0 4 4 4 2 PPR repeat family PPR_1 PF12854.7 CDO74179.1 - 0.00011 21.8 0.0 1.3 8.8 0.0 3.8 4 0 0 4 4 4 2 PPR repeat PPR PF01535.20 CDO74179.1 - 0.0017 18.5 0.5 0.86 10.0 0.0 4.8 6 0 0 6 6 6 1 PPR repeat PPR_3 PF13812.6 CDO74179.1 - 0.03 14.4 0.0 3.3 7.8 0.0 3.9 4 0 0 4 4 4 0 Pentatricopeptide repeat domain FAD_binding_3 PF01494.19 CDO74180.1 - 7.5e-21 74.8 0.0 3e-19 69.5 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CDO74180.1 - 0.00066 19.9 0.5 0.0017 18.5 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 CDO74180.1 - 0.042 12.9 0.0 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_3 PF01494.19 CDO74181.1 - 1e-24 87.4 0.1 4.7e-24 85.3 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CDO74181.1 - 3.2e-05 24.1 0.1 7.3e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CDO74181.1 - 0.00043 19.5 0.1 0.0021 17.2 0.1 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 CDO74181.1 - 0.00088 18.2 0.2 0.0075 15.2 0.1 2.0 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 CDO74181.1 - 0.006 15.9 0.4 0.1 11.8 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO74181.1 - 0.049 13.6 0.3 0.61 10.1 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 CDO74181.1 - 0.065 13.8 0.1 0.15 12.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDO74181.1 - 0.082 11.6 0.0 0.33 9.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Peptidase_S9_N PF02897.15 CDO74182.1 - 4.2e-93 312.4 3.6 6.3e-93 311.8 3.6 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CDO74182.1 - 3.1e-30 105.3 0.1 4.7e-17 62.2 0.0 3.5 3 0 0 3 3 3 3 Prolyl oligopeptidase family DUF4811 PF16069.5 CDO74182.1 - 0.0092 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4811) CheW PF01584.19 CDO74182.1 - 0.18 11.4 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 CheW-like domain Mito_carr PF00153.27 CDO74183.1 - 9.9e-64 211.3 1.7 1.2e-20 73.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.23 CDO74184.1 - 2.5e-23 81.9 0.6 3.7e-23 81.3 0.6 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDO74184.1 - 5e-23 81.4 0.1 7.8e-23 80.8 0.1 1.4 1 1 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CDO74184.1 - 0.00012 22.2 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 CDO74184.1 - 0.0015 18.6 0.0 0.002 18.2 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 Bd3614-deam PF14439.6 CDO74184.1 - 0.002 18.2 1.4 0.031 14.4 1.4 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase NAD1 PF18778.1 CDO74184.1 - 0.0025 17.9 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 CDO74184.1 - 0.0039 17.3 0.0 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 APOBEC3 APOBEC1 PF18769.1 CDO74184.1 - 0.0092 16.2 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 APOBEC1 APOBEC_N PF08210.11 CDO74184.1 - 0.014 15.3 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD2 PF18782.1 CDO74184.1 - 0.019 15.1 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC4_like PF18774.1 CDO74184.1 - 0.037 14.0 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Pkinase_fungal PF17667.1 CDO74185.1 - 3.8e-49 167.6 0.0 1.1e-34 120.0 0.0 2.8 2 1 0 2 2 2 2 Fungal protein kinase APH PF01636.23 CDO74185.1 - 0.077 12.9 1.0 0.47 10.3 0.2 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 CDO74186.1 - 1.1e-29 103.6 0.3 1.8e-29 102.9 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 CDO74186.1 - 2.6e-18 65.9 0.0 5.2e-18 65.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 CDO74186.1 - 3.3e-18 65.7 0.1 7.1e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CDO74186.1 - 2.4e-14 53.9 0.0 6.1e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CDO74186.1 - 6.3e-06 26.5 0.1 1.2e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SNF2_N PF00176.23 CDO74187.1 - 9.2e-56 189.0 0.0 1.4e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Epimerase PF01370.21 CDO74187.1 - 5.7e-36 124.2 0.0 1.2e-35 123.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDO74187.1 - 1.1e-19 71.1 0.0 2.2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glycos_transf_2 PF00535.26 CDO74187.1 - 1.1e-14 54.6 1.6 3e-14 53.2 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Helicase_C PF00271.31 CDO74187.1 - 7.6e-14 52.0 0.0 2.3e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 3Beta_HSD PF01073.19 CDO74187.1 - 4.2e-08 32.5 0.0 7.6e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ResIII PF04851.15 CDO74187.1 - 2.3e-07 31.0 0.4 9.7e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Glyco_tranf_2_3 PF13641.6 CDO74187.1 - 8.4e-07 29.1 0.1 5.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 NAD_binding_10 PF13460.6 CDO74187.1 - 1.5e-06 28.3 1.4 4.7e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding zf-RING_2 PF13639.6 CDO74187.1 - 2e-05 24.8 5.5 2e-05 24.8 5.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CDO74187.1 - 3.6e-05 23.5 5.6 7.9e-05 22.4 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CDO74187.1 - 0.00041 20.2 0.0 0.00099 18.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase NmrA PF05368.13 CDO74187.1 - 0.00067 19.3 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family zf-C3HC4_2 PF13923.6 CDO74187.1 - 0.00077 19.3 4.1 0.0021 17.9 4.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Glyco_tranf_2_2 PF10111.9 CDO74187.1 - 0.00077 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 zf-C3HC4_4 PF15227.6 CDO74187.1 - 0.00098 19.2 5.1 0.0022 18.1 5.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CDO74187.1 - 0.002 18.0 4.3 0.0044 16.9 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CDO74187.1 - 0.002 17.9 2.1 0.0046 16.8 2.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 CDO74187.1 - 0.0023 18.2 2.8 0.0051 17.1 2.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CDO74187.1 - 0.0032 17.3 4.2 0.0073 16.1 4.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CDO74187.1 - 0.12 12.4 4.7 0.18 11.9 3.4 2.0 2 0 0 2 2 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 CDO74187.1 - 0.21 11.6 3.6 0.073 13.1 0.4 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CDO74187.1 - 0.55 10.2 5.6 1.2 9.2 5.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_transf_8 PF01501.20 CDO74188.1 - 9.5e-28 97.4 0.0 1.6e-24 86.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 8 Methyltransf_24 PF13578.6 CDO74188.1 - 7.3e-17 62.3 0.1 2.5e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Glyco_transf_24 PF18404.1 CDO74188.1 - 8.5e-06 25.4 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Methyltransf_3 PF01596.17 CDO74188.1 - 9.6e-05 21.6 0.0 0.00023 20.4 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase WW PF00397.26 CDO74189.1 - 1.3e-09 38.0 5.8 2.9e-09 36.9 5.8 1.6 1 0 0 1 1 1 1 WW domain HMG_box PF00505.19 CDO74190.1 - 2.4e-16 59.9 2.6 2.4e-16 59.9 2.6 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CDO74190.1 - 2.2e-10 41.0 2.6 2.2e-10 41.0 2.6 1.9 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.13 CDO74190.1 - 2.6e-05 24.8 0.4 2.6e-05 24.8 0.4 1.8 2 0 0 2 2 2 1 YABBY protein Protamine_like PF06382.11 CDO74190.1 - 0.018 15.3 0.6 0.03 14.5 0.6 1.4 1 0 0 1 1 1 0 Protamine and protamine like CHDNT PF08073.12 CDO74190.1 - 0.025 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain NICE-1 PF15845.5 CDO74190.1 - 0.2 12.5 0.4 0.41 11.4 0.4 1.5 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family GAGA_bind PF06217.12 CDO74190.1 - 3.6 7.8 12.5 0.28 11.4 0.8 2.2 1 1 1 2 2 2 0 GAGA binding protein-like family Med26 PF08711.11 CDO74191.1 - 1.2e-06 28.4 0.1 3e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 TFIIS helical bundle-like domain Acid_PPase PF12689.7 CDO74191.1 - 0.07 13.0 0.5 0.15 11.9 0.5 1.5 1 0 0 1 1 1 0 Acid Phosphatase LIM_bind PF01803.16 CDO74192.1 - 1.3e-49 169.0 0.0 1.3e-49 169.0 0.0 2.9 2 1 0 2 2 2 1 LIM-domain binding protein Kinesin PF00225.23 CDO74193.1 - 3.9e-109 364.6 0.0 6.9e-109 363.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 CDO74193.1 - 4.3e-44 150.9 0.0 1.3e-43 149.3 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 CDO74193.1 - 6.3e-32 111.2 8.9 8.5e-24 84.7 3.1 3.6 1 1 1 2 2 2 2 Kinesin-associated Microtub_bd PF16796.5 CDO74193.1 - 1.2e-20 74.0 0.0 4e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 CDO74193.1 - 2.5e-09 37.6 0.0 1e-08 35.6 0.0 2.0 2 0 0 2 2 2 1 PH domain KIF1B PF12423.8 CDO74193.1 - 6.8e-05 23.2 0.6 0.00032 21.1 0.6 2.2 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 CDO74193.1 - 0.00042 20.6 0.0 0.002 18.5 0.0 2.2 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.6 CDO74193.1 - 0.15 12.5 0.0 0.56 10.7 0.0 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain PilJ PF13675.6 CDO74193.1 - 0.36 10.9 12.1 0.041 13.9 1.7 3.4 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term EAP30 PF04157.16 CDO74193.1 - 1.8 7.8 9.1 0.13 11.5 1.1 2.8 2 0 0 2 2 2 0 EAP30/Vps36 family Ribosomal_S4 PF00163.19 CDO74194.1 - 2.6e-13 50.7 0.4 3.7e-13 50.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 CDO74194.1 - 2.3e-11 43.2 0.0 3.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 S4 domain Cyt-b5 PF00173.28 CDO74196.1 - 3.6e-14 52.7 0.1 6.7e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arf PF00025.21 CDO74197.1 - 3.3e-61 205.8 1.2 3.7e-60 202.4 1.2 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CDO74197.1 - 4e-09 36.1 0.5 2.4e-05 23.6 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CDO74197.1 - 9.8e-06 25.1 0.0 2.6e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CDO74197.1 - 3.2e-05 24.0 0.0 4.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CDO74197.1 - 0.0005 20.3 0.0 0.0015 18.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 CDO74197.1 - 0.048 13.6 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PIH1 PF08190.12 CDO74197.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PIH1 N-terminal domain GTP_EFTU PF00009.27 CDO74198.1 - 3.1e-34 118.2 0.0 3.7e-33 114.7 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CDO74198.1 - 3.1e-19 69.0 0.0 8.9e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CDO74198.1 - 4.9e-13 49.3 9.9 2.5e-10 40.6 0.1 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDO74198.1 - 4.3e-07 30.0 0.1 6.7e-06 26.2 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 CDO74198.1 - 0.00015 21.9 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 CDO74198.1 - 0.00065 19.6 0.6 0.011 15.7 0.6 2.8 1 1 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.17 CDO74198.1 - 0.0022 17.8 0.0 0.006 16.4 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 CDO74198.1 - 0.054 13.1 0.0 0.25 10.9 0.0 2.2 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.6 CDO74198.1 - 0.12 12.7 0.3 1.4 9.2 0.3 2.4 1 1 0 1 1 1 0 AAA domain AA_permease_2 PF13520.6 CDO74199.1 - 3.6e-43 148.0 52.4 4.9e-43 147.5 52.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDO74199.1 - 1.4e-21 76.7 40.2 1.8e-21 76.3 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease AMP_N PF05195.16 CDO74200.1 - 7.2e-28 96.8 0.0 1.1e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.24 CDO74201.1 - 1.5e-27 96.7 0.0 2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2433 PF10360.9 CDO74203.1 - 3.8e-42 143.3 0.0 8.9e-42 142.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 CDO74203.1 - 0.00082 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 CDO74203.1 - 0.026 15.0 0.0 0.055 14.0 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDO74203.1 - 0.069 13.3 0.0 0.25 11.5 0.0 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CENP-N PF05238.13 CDO74203.1 - 0.28 10.4 2.3 0.41 9.9 2.3 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Rrn6 PF10214.9 CDO74203.1 - 1.9 6.9 11.8 2.8 6.3 11.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Hamartin PF04388.12 CDO74203.1 - 3.8 6.1 9.0 5.8 5.4 9.0 1.2 1 0 0 1 1 1 0 Hamartin protein DUF3043 PF11241.8 CDO74203.1 - 4.3 7.3 13.2 8.4 6.4 13.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) NARP1 PF12569.8 CDO74203.1 - 9.2 5.0 9.2 13 4.5 9.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Med13_C PF06333.12 CDO74204.1 - 9.9e-41 140.1 4.4 9.9e-41 140.1 4.4 3.3 2 2 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 CDO74204.1 - 3.3e-18 66.1 1.8 6.7e-18 65.1 0.1 2.2 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MerR PF00376.23 CDO74204.1 - 0.11 12.3 0.1 0.52 10.1 0.0 2.2 2 0 0 2 2 2 0 MerR family regulatory protein Cerato-platanin PF07249.12 CDO74205.1 - 4.7e-47 159.0 0.6 5.5e-47 158.8 0.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Plant_tran PF04827.14 CDO74205.1 - 0.12 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein Cerato-platanin PF07249.12 CDO74206.1 - 2.5e-48 163.1 1.0 2.9e-48 162.9 1.0 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 CDO74206.1 - 0.024 14.5 0.2 0.063 13.1 0.1 1.7 2 0 0 2 2 2 0 Barwin family Plant_tran PF04827.14 CDO74206.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein Acyl-CoA_dh_1 PF00441.24 CDO74207.1 - 1.2e-40 139.2 3.0 1.8e-40 138.6 3.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CDO74207.1 - 6.5e-32 110.5 0.7 4.5e-31 107.8 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CDO74207.1 - 1.3e-22 79.8 0.0 2.3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CDO74207.1 - 4.2e-18 65.9 1.6 6.7e-18 65.3 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CDO74207.1 - 0.00066 20.2 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Mito_carr PF00153.27 CDO74208.1 - 4.6e-33 113.0 3.9 2.3e-15 56.3 0.7 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 CDO74208.1 - 0.00097 19.0 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like KxDL PF10241.9 CDO74209.1 - 0.0025 18.1 2.7 0.049 13.9 0.3 3.2 3 0 0 3 3 3 1 Uncharacterized conserved protein EF-hand_6 PF13405.6 CDO74209.1 - 0.084 12.8 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain Spt4 PF06093.13 CDO74211.1 - 1.2e-30 105.5 0.2 1.4e-30 105.2 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Thioredoxin_2 PF13098.6 CDO74211.1 - 0.025 15.0 0.0 0.034 14.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain RAI1 PF08652.11 CDO74212.1 - 2.7e-22 78.7 0.0 5.3e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Lipase_3 PF01764.25 CDO74213.1 - 3.3e-13 49.7 0.0 8.3e-12 45.2 0.0 2.4 2 0 0 2 2 2 1 Lipase (class 3) Haem_degrading PF03928.14 CDO74214.1 - 4.3e-36 123.6 0.1 5.1e-36 123.3 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading MIT_LIKE_ACTX PF17556.2 CDO74214.1 - 0.092 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 MIT-like atracotoxin family DUF3818 PF12825.7 CDO74215.1 - 0.033 13.2 1.5 0.055 12.5 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF2524 PF10732.9 CDO74215.1 - 3.4 8.0 8.5 0.66 10.3 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) DUF4219 PF13961.6 CDO74218.1 - 5.6e-08 32.3 0.7 8.8e-08 31.6 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 CDO74218.1 - 3.9e-07 29.8 0.0 6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 CDO74218.1 - 4.1e-06 26.5 0.5 6.1e-06 26.0 0.5 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Bombolitin PF08096.11 CDO74218.1 - 0.19 12.1 0.2 0.33 11.3 0.2 1.4 1 0 0 1 1 1 0 Bombolitin family COesterase PF00135.28 CDO74219.1 - 1.2e-05 24.4 0.0 6.4e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family PS_Dcarbxylase PF02666.15 CDO74221.1 - 8.9e-15 54.8 0.0 1.2e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Dna2 PF08696.11 CDO74222.1 - 3.1e-55 187.2 0.0 5.5e-55 186.3 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 CDO74222.1 - 6.7e-51 172.8 0.0 1.1e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CDO74222.1 - 3.8e-31 108.8 0.1 5.8e-17 62.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CDO74222.1 - 5.4e-15 55.6 0.0 1.3e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDO74222.1 - 2.6e-11 44.0 0.0 7.5e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CDO74222.1 - 5.4e-05 23.1 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 CDO74222.1 - 0.00039 20.2 0.1 0.48 10.1 0.0 3.4 2 1 1 3 3 3 1 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 CDO74222.1 - 0.00039 20.6 0.1 0.0035 17.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 AAA_16 PF13191.6 CDO74222.1 - 0.0008 19.8 0.0 0.0023 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CDO74222.1 - 0.0013 19.1 0.0 0.0036 17.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 CDO74222.1 - 0.0023 17.5 0.1 0.0036 16.9 0.1 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 CDO74222.1 - 0.0027 16.9 0.1 0.024 13.8 0.1 2.0 1 1 0 1 1 1 1 PIF1-like helicase DUF2075 PF09848.9 CDO74222.1 - 0.021 14.1 0.2 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CDO74222.1 - 0.023 14.2 0.0 0.23 10.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF87 PF01935.17 CDO74222.1 - 0.024 14.8 0.3 0.051 13.7 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain ResIII PF04851.15 CDO74222.1 - 0.029 14.4 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MeaB PF03308.16 CDO74222.1 - 0.031 13.3 0.0 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CDO74222.1 - 0.033 14.4 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CDO74222.1 - 0.046 13.5 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 CDO74222.1 - 0.047 13.3 0.4 0.08 12.6 0.4 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 CDO74222.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.14 CDO74222.1 - 0.092 12.7 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DpaA_N PF16924.5 CDO74222.1 - 0.1 12.7 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain AAA_18 PF13238.6 CDO74222.1 - 0.12 12.9 0.0 0.39 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CDO74222.1 - 0.13 12.1 0.3 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 CDO74222.1 - 0.15 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase YL1_C PF08265.11 CDO74223.1 - 3.5e-14 52.3 0.3 6.7e-14 51.3 0.3 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CPL PF08144.11 CDO74224.1 - 1.4e-36 126.0 0.0 1.1e-33 116.6 0.0 3.2 3 0 0 3 3 3 2 CPL (NUC119) domain DUF2267 PF10025.9 CDO74224.1 - 7.2 6.9 9.0 2.3 8.5 0.4 3.6 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2267) Plavaka PF18759.1 CDO74225.1 - 1.9e-108 362.5 0.0 3e-108 361.9 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-CCHC PF00098.23 CDO74229.1 - 4e-06 26.6 2.2 6.1e-06 26.1 2.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDO74229.1 - 0.00085 19.1 3.2 0.0014 18.4 3.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDO74229.1 - 0.011 15.7 0.5 0.017 15.1 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.14 CDO74230.1 - 1.9e-70 237.3 0.0 2.6e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO74230.1 - 1.6e-19 70.2 0.0 5.1e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO74230.1 - 5e-09 35.9 0.3 1.2e-08 34.7 0.3 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 CDO74230.1 - 0.002 17.8 2.1 0.0021 17.7 0.3 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 CDO74230.1 - 0.0026 17.5 0.0 0.0076 16.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF4820 PF16091.5 CDO74230.1 - 0.41 10.0 1.7 0.74 9.1 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4219 PF13961.6 CDO74231.1 - 0.019 14.6 0.8 0.21 11.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) MRNIP PF15749.5 CDO74232.1 - 1.1 10.0 6.6 1.3 9.8 6.6 1.2 1 0 0 1 1 1 0 MRN-interacting protein Coilin_N PF15862.5 CDO74232.1 - 2.1 8.1 14.7 0.55 10.0 11.7 1.5 1 1 1 2 2 2 0 Coilin N-terminus Asp-B-Hydro_N PF05279.11 CDO74232.1 - 5.5 7.0 16.5 6.5 6.8 16.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Integrase_H2C2 PF17921.1 CDO74233.1 - 5.8e-15 55.1 0.3 1.3e-14 54.0 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO74233.1 - 8.3e-13 48.6 0.0 1.6e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDO74233.1 - 2.6e-08 33.9 0.1 4.8e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Ferrochelatase PF00762.19 CDO74233.1 - 0.065 12.3 0.3 5.5 6.0 0.0 2.1 1 1 1 2 2 2 0 Ferrochelatase Chromo PF00385.24 CDO74235.1 - 1.1e-07 31.6 0.1 1.8e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Spc7 PF08317.11 CDO74236.1 - 0.0049 15.8 1.7 0.0058 15.5 1.7 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-Q PF13094.6 CDO74236.1 - 0.034 14.4 8.6 0.042 14.1 8.6 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Methyltransf_1N PF02870.15 CDO74236.1 - 0.083 13.7 0.3 0.11 13.4 0.3 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain RP-C_C PF11800.8 CDO74236.1 - 0.17 11.9 2.7 0.19 11.8 2.7 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2457 PF10446.9 CDO74236.1 - 3.6 6.6 12.0 3.7 6.6 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 CDO74236.1 - 6.6 6.0 6.6 7.8 5.7 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein LRR_4 PF12799.7 CDO74237.1 - 0.3 11.6 4.3 42 4.7 0.1 4.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Aldedh PF00171.22 CDO74240.1 - 1.1e-49 169.2 0.0 7.2e-29 100.6 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family COPIIcoated_ERV PF07970.12 CDO74241.1 - 6.3e-36 124.3 0.8 9.8e-36 123.7 0.8 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CDO74241.1 - 5.4e-23 81.2 0.0 9.2e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Hva1_TUDOR PF11160.8 CDO74242.1 - 2.2e-14 53.4 1.7 3.6e-14 52.6 1.7 1.4 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain HTH_23 PF13384.6 CDO74243.1 - 0.00015 21.4 0.2 0.00035 20.3 0.1 1.6 2 0 0 2 2 2 1 Homeodomain-like domain BTAD PF03704.17 CDO74244.1 - 0.21 12.0 0.0 0.26 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial transcriptional activator domain DUF3669 PF12417.8 CDO74247.1 - 8.9e-06 25.8 0.0 2.3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Zinc finger protein Cyt-b5 PF00173.28 CDO74248.1 - 2.9e-05 24.1 0.1 2.9e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MARVEL PF01284.23 CDO74249.1 - 1e-09 38.5 7.1 1.6e-09 37.9 7.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain GT87 PF09594.10 CDO74249.1 - 0.0026 17.5 1.2 0.0045 16.7 1.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 87 MIG-14_Wnt-bd PF06664.12 CDO74249.1 - 0.019 14.2 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF456 PF04306.13 CDO74249.1 - 8.5 6.7 13.1 0.24 11.7 6.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF456) DUF659 PF04937.15 CDO74250.1 - 3.1e-09 36.9 0.2 6e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3306 PF11748.8 CDO74250.1 - 1.1 10.2 4.9 0.27 12.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Terpene_synth_C PF03936.16 CDO74251.1 - 0.00097 18.6 0.0 0.0019 17.6 0.0 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain RNA_pol_Rpb5_C PF01191.19 CDO74252.1 - 2e-32 110.9 0.1 4.4e-32 109.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CDO74252.1 - 9.8e-30 103.0 0.1 1.8e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 CDO74252.1 - 0.00079 19.4 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease R3H PF01424.22 CDO74252.1 - 0.047 13.7 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 R3H domain WD40 PF00400.32 CDO74253.1 - 2.2e-13 50.5 3.3 0.0001 23.0 0.2 4.6 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO74253.1 - 1.6e-05 25.1 0.0 0.1 12.9 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PAS_8 PF13188.7 CDO74253.1 - 0.069 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 PAS domain TRAP_alpha PF03896.16 CDO74254.1 - 2.1e-06 27.2 0.0 0.0046 16.2 0.0 2.0 2 0 0 2 2 2 2 Translocon-associated protein (TRAP), alpha subunit MitoNEET_N PF10660.9 CDO74254.1 - 0.019 15.0 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus ABA_WDS PF02496.16 CDO74254.1 - 0.032 14.7 0.0 0.053 14.0 0.0 1.3 1 0 0 1 1 1 0 ABA/WDS induced protein FAM176 PF14851.6 CDO74255.1 - 0.13 11.9 4.6 0.1 12.3 3.7 1.4 1 1 0 1 1 1 0 FAM176 family Transposase_21 PF02992.14 CDO74258.1 - 2.3e-05 23.8 0.0 4.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 CDO74258.1 - 0.014 14.6 0.2 0.023 13.9 0.2 1.3 1 0 0 1 1 1 0 Plavaka transposase DUF3987 PF13148.6 CDO74258.1 - 0.17 10.8 0.3 0.35 9.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) zinc-ribbons_6 PF07191.12 CDO74258.1 - 0.58 10.2 4.1 1.1 9.3 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbons RT_RNaseH PF17917.1 CDO74260.1 - 1.3e-39 134.7 0.0 2.7e-39 133.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO74260.1 - 7.1e-38 128.7 0.0 1.5e-37 127.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO74260.1 - 7.2e-23 81.3 0.1 1.5e-22 80.2 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PEPCK_ATP PF01293.20 CDO74264.1 - 1.1e-217 723.3 0.0 1.3e-217 723.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DASH_Dad2 PF08654.10 CDO74264.1 - 7.1e-08 32.8 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad2 AAA_33 PF13671.6 CDO74264.1 - 0.002 18.3 0.0 0.06 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDO74264.1 - 0.011 16.1 0.1 0.097 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CDO74264.1 - 0.079 12.7 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Palm_thioest PF02089.15 CDO74265.1 - 3.4e-76 256.3 0.0 3.8e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 CDO74265.1 - 0.034 13.8 0.0 0.053 13.2 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DCAF15_WD40 PF14939.6 CDO74265.1 - 0.21 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat DUF915 PF06028.11 CDO74265.1 - 0.25 10.7 0.0 0.49 9.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) ERAP1_C PF11838.8 CDO74266.1 - 4.3e-63 213.7 0.8 4.3e-63 213.7 0.8 1.5 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CDO74266.1 - 1.7e-62 210.9 0.3 3.3e-62 209.9 0.3 1.5 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDO74266.1 - 2.8e-38 132.0 0.0 9.6e-37 127.0 0.0 2.4 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Sad1_UNC PF07738.13 CDO74268.1 - 9.7e-21 74.2 0.0 1.5e-17 63.9 0.0 2.2 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Transposase_21 PF02992.14 CDO74271.1 - 4.1e-16 58.9 0.0 8.1e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 CDO74271.1 - 0.018 14.6 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DUF4218 PF13960.6 CDO74271.1 - 0.041 13.5 0.1 0.094 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Plavaka PF18759.1 CDO74271.1 - 0.071 12.3 0.1 0.2 10.9 0.1 1.7 1 0 0 1 1 1 0 Plavaka transposase DUF4131 PF13567.6 CDO74271.1 - 3.3 7.3 5.2 2.9 7.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Myb_DNA-bind_3 PF12776.7 CDO74272.1 - 2.7e-09 37.9 0.1 4.3e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO74272.1 - 5.7e-09 36.2 0.1 1e-08 35.4 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO74272.1 - 0.00086 19.3 0.1 0.0033 17.5 0.1 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myc_N PF01056.18 CDO74272.1 - 0.0014 18.6 1.1 0.0022 17.9 1.1 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Myb_DNA-binding PF00249.31 CDO74272.1 - 0.0081 16.3 0.3 0.019 15.2 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain CENP-B_dimeris PF09026.10 CDO74272.1 - 0.013 15.9 6.3 0.027 14.9 6.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TAL_effector PF03377.13 CDO74272.1 - 0.066 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 TAL effector repeat Myb_DNA-bind_6 PF13921.6 CDO74272.1 - 0.09 13.0 0.2 0.24 11.7 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain RRN3 PF05327.11 CDO74272.1 - 0.35 9.4 2.2 0.44 9.0 2.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.6 CDO74272.1 - 0.88 10.0 6.9 2.8 8.4 5.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 CDO74272.1 - 2.7 6.0 7.1 3.9 5.5 7.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 CDO74272.1 - 5.1 6.3 7.2 8 5.7 7.2 1.2 1 0 0 1 1 1 0 NOA36 protein Syntaxin_2 PF14523.6 CDO74273.1 - 3.8e-21 75.3 6.1 2.4e-20 72.8 2.3 2.7 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 CDO74273.1 - 1.5e-09 37.7 0.4 3.9e-09 36.4 0.4 1.7 1 0 0 1 1 1 1 SNARE domain DDE_Tnp_4 PF13359.6 CDO74273.1 - 7.6e-09 35.4 0.0 2.2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease Syntaxin PF00804.25 CDO74273.1 - 4.5e-07 29.8 10.8 1.2e-06 28.3 10.8 1.8 1 1 0 1 1 1 1 Syntaxin Plant_tran PF04827.14 CDO74273.1 - 0.00013 21.7 0.1 0.00024 20.8 0.1 1.4 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO74273.1 - 0.00017 21.9 0.3 0.0036 17.6 0.1 2.5 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 CDO74273.1 - 0.017 14.8 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain DUF202 PF02656.15 CDO74274.1 - 3e-19 69.2 2.6 3e-19 69.2 2.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MscS_TM PF12794.7 CDO74274.1 - 0.0092 14.9 5.7 0.013 14.4 5.7 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 DUF2243 PF10002.9 CDO74274.1 - 0.095 12.8 0.9 0.12 12.4 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) SdpI PF13630.6 CDO74274.1 - 0.18 11.9 3.7 0.33 11.1 3.7 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF3784 PF12650.7 CDO74274.1 - 2 8.7 8.9 3.7 7.8 8.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) TMEM43 PF07787.12 CDO74274.1 - 2.9 7.2 4.3 3.9 6.8 4.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 43 Spore_coat_CotO PF14153.6 CDO74275.1 - 0.39 10.6 14.5 0.44 10.5 14.5 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Zip PF02535.22 CDO74275.1 - 6.3 5.9 6.6 6.5 5.9 6.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter zf-CCHC PF00098.23 CDO74276.1 - 1.9e-05 24.5 2.1 3.4e-05 23.7 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 CDO74276.1 - 0.0025 17.5 2.2 0.0046 16.7 2.2 1.3 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_6 PF15288.6 CDO74276.1 - 0.031 14.1 0.3 0.058 13.2 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 CDO74276.1 - 0.052 13.3 0.5 0.09 12.5 0.5 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF5082 PF16888.5 CDO74277.1 - 0.0029 17.9 0.5 0.005 17.1 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) CENP-F_leu_zip PF10473.9 CDO74277.1 - 0.0075 16.3 0.5 0.013 15.5 0.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CobT_C PF11775.8 CDO74278.1 - 0.11 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain rve PF00665.26 CDO74279.1 - 1.2e-18 67.4 0.3 2.8e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO74279.1 - 1.9e-10 40.5 0.3 3.2e-10 39.8 0.3 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO74279.1 - 3.9e-09 36.2 0.3 8.4e-09 35.2 0.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_2 PF07727.14 CDO74279.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CDO74279.1 - 0.021 14.6 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF4820 PF16091.5 CDO74279.1 - 0.27 10.6 1.5 0.47 9.8 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Carboxyl_trans PF01039.22 CDO74280.1 - 4.1e-132 441.3 0.4 5.4e-132 440.9 0.4 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CDO74280.1 - 0.00022 20.8 0.4 0.0013 18.3 0.1 2.1 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) WD40 PF00400.32 CDO74281.1 - 0.015 16.2 9.8 0.03 15.2 0.6 3.5 4 1 0 4 4 4 0 WD domain, G-beta repeat DUF1933 PF09147.10 CDO74281.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) DUF4597 PF15366.6 CDO74282.1 - 0.43 10.4 2.6 2 8.2 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) Mg_trans_NIPA PF05653.14 CDO74283.1 - 4.5e-60 203.2 7.4 1.4e-57 195.1 3.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 CDO74283.1 - 3.8e-05 23.9 3.9 3.8e-05 23.9 3.9 3.4 3 1 0 3 3 3 1 EamA-like transporter family HlyIII PF03006.20 CDO74283.1 - 2.6 7.7 7.6 18 4.9 7.6 2.2 1 1 0 1 1 1 0 Haemolysin-III related WD40 PF00400.32 CDO74285.1 - 2.7e-08 34.3 0.0 0.00064 20.5 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO74285.1 - 0.00013 22.2 0.0 0.018 15.3 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain RelB_transactiv PF16181.5 CDO74285.1 - 0.096 12.9 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 RelB transactivation domain TFIID-31kDa PF02291.15 CDO74286.1 - 7.7e-36 122.8 0.0 1.1e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CDO74286.1 - 0.00018 21.6 0.0 0.00056 20.0 0.0 1.9 2 1 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold FMN_red PF03358.15 CDO74286.1 - 0.0072 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase CENP-S PF15630.6 CDO74286.1 - 0.023 15.1 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 CENP-S protein Bromo_TP PF07524.13 CDO74286.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated MBOAT PF03062.19 CDO74287.1 - 3.4e-42 145.0 5.2 1.9e-41 142.6 5.2 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.11 CDO74287.1 - 0.16 12.3 0.3 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) SSB PF00436.25 CDO74288.1 - 1.4e-16 60.4 0.0 1.8e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family GTP_EFTU PF00009.27 CDO74289.1 - 1.3e-43 148.8 0.0 2.5e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 CDO74289.1 - 1.5e-17 63.6 1.9 3.6e-17 62.4 1.9 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 CDO74289.1 - 5.5e-10 39.5 0.0 1.8e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CDO74289.1 - 1.5e-05 25.0 0.0 0.001 19.1 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Pkinase PF00069.25 CDO74292.1 - 0.0034 16.8 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDO74292.1 - 0.011 14.5 0.0 0.013 14.3 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Retrotran_gag_2 PF14223.6 CDO74294.1 - 4.9e-25 87.8 0.0 6.2e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO74294.1 - 7.2e-07 29.0 3.4 1.2e-06 28.3 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDO74294.1 - 0.06 13.3 1.5 0.13 12.2 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_3 PF14244.6 CDO74294.1 - 0.17 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_1 PF00078.27 CDO74296.1 - 5.7e-21 75.0 0.0 7.9e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CDO74296.1 - 4.9e-07 29.6 0.0 9.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDO74296.1 - 3e-06 27.8 0.0 5.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDO74296.1 - 0.0041 17.6 0.0 0.0069 16.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 CDO74296.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase DUF4939 PF16297.5 CDO74297.1 - 8.5e-09 35.3 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 CDO74297.1 - 5.3e-05 23.4 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 CDO74298.1 - 1.6e-26 92.6 0.0 2e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO74298.1 - 7.4e-08 32.1 2.9 1.3e-07 31.3 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDO74298.1 - 0.0059 16.5 0.5 0.014 15.3 0.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDO74298.1 - 0.89 9.4 5.1 1.6 8.6 5.1 1.5 1 0 0 1 1 1 0 Zinc knuckle RNase_H PF00075.24 CDO74300.1 - 0.024 14.8 0.1 0.028 14.6 0.1 1.3 1 1 0 1 1 1 0 RNase H Torsin PF06309.11 CDO74300.1 - 0.06 13.5 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Torsin Prog_receptor PF02161.15 CDO74300.1 - 0.17 10.6 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 Progesterone receptor OPT PF03169.15 CDO74303.1 - 4.6e-135 451.7 26.7 5.7e-135 451.3 26.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 CDO74303.1 - 0.33 11.0 5.4 0.65 10.0 0.4 3.2 2 0 0 2 2 2 0 Bacteriophage P21 holin S YchF-GTPase_C PF06071.13 CDO74304.1 - 2.8e-35 120.4 0.0 1e-34 118.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CDO74304.1 - 1.9e-17 63.4 0.0 5.5e-17 61.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CDO74304.1 - 2.5e-05 23.9 0.0 4.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B BetaGal_dom3 PF13363.6 CDO74304.1 - 0.028 14.0 0.1 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 MeaB PF03308.16 CDO74304.1 - 0.093 11.7 0.3 0.29 10.1 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AD PF09793.9 CDO74304.1 - 0.1 12.8 1.0 0.16 12.2 0.1 1.8 2 0 0 2 2 2 0 Anticodon-binding domain RPAP1_N PF08621.10 CDO74304.1 - 0.1 12.4 2.7 0.2 11.4 2.7 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal Plavaka PF18759.1 CDO74305.1 - 5e-26 91.7 0.4 1.9e-25 89.8 0.1 2.1 2 1 0 2 2 2 1 Plavaka transposase 4HBT PF03061.22 CDO74306.1 - 0.0026 18.1 0.1 0.0069 16.7 0.0 1.8 2 0 0 2 2 2 1 Thioesterase superfamily TauD PF02668.16 CDO74307.1 - 2.2e-52 178.5 0.2 2.7e-52 178.2 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EF-hand_1 PF00036.32 CDO74308.1 - 2e-27 92.6 15.9 3.1e-09 35.7 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDO74308.1 - 2.2e-27 95.3 13.0 4.1e-14 52.8 3.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDO74308.1 - 3.8e-23 79.4 10.8 1.7e-08 33.7 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CDO74308.1 - 1e-14 54.1 13.2 3.6e-09 36.3 1.2 3.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CDO74308.1 - 6.6e-12 44.4 7.4 0.00078 18.8 1.2 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 CDO74308.1 - 2.8e-10 40.4 1.7 0.00043 20.6 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDO74308.1 - 3.5e-09 36.5 6.3 0.00016 21.5 0.1 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CDO74308.1 - 0.00045 20.2 2.2 0.19 11.6 0.0 3.5 2 1 2 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 CDO74308.1 - 0.0026 18.1 3.2 0.33 11.3 0.2 2.2 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CDO74308.1 - 0.02 15.2 2.9 0.22 11.9 0.4 2.3 2 1 0 2 2 2 0 EF-hand domain DUF1059 PF06348.11 CDO74308.1 - 0.035 14.3 0.3 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) DUF1636 PF07845.11 CDO74308.1 - 0.083 13.3 0.0 2.4 8.6 0.0 2.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1636) zf-C2H2 PF00096.26 CDO74309.1 - 1.2e-09 38.1 11.0 0.00017 21.8 2.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO74309.1 - 5.6e-06 26.6 3.7 5.6e-06 26.6 3.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDO74309.1 - 2.7e-05 24.6 10.4 0.012 16.4 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 CDO74309.1 - 0.0032 18.1 3.0 0.3 11.7 0.4 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 CDO74309.1 - 0.13 12.1 10.1 0.69 9.7 1.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 CDO74309.1 - 1.3 9.2 5.3 9.9 6.3 1.4 2.2 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 CDO74309.1 - 2.9 8.0 6.4 0.51 10.4 1.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Retrotrans_gag PF03732.17 CDO74310.1 - 1.1e-12 48.0 0.1 3.7e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO74310.1 - 6.9e-09 35.6 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Apt1 PF10351.9 CDO74310.1 - 2.3 7.0 7.2 3.6 6.3 7.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM199X PF15814.5 CDO74310.1 - 2.9 6.9 10.6 4.5 6.2 10.6 1.2 1 0 0 1 1 1 0 Protein family FAM199X NPR3 PF03666.13 CDO74310.1 - 4.5 5.9 5.7 7.6 5.2 5.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AF-4 PF05110.13 CDO74311.1 - 0.75 7.8 4.0 0.59 8.2 4.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DRY_EERY PF09750.9 CDO74312.1 - 0.00093 19.5 1.2 0.0023 18.2 0.6 2.0 2 0 0 2 2 2 1 Alternative splicing regulator Surp PF01805.20 CDO74312.1 - 0.074 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Surp module FAM176 PF14851.6 CDO74312.1 - 2.8 7.6 9.7 4.3 7.0 0.4 2.9 2 1 1 3 3 3 0 FAM176 family Piwi PF02171.17 CDO74313.1 - 1.6e-73 247.6 0.0 2.4e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CDO74313.1 - 8.2e-19 68.6 0.3 2.3e-18 67.1 0.1 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CDO74313.1 - 9.4e-17 60.4 0.2 2.6e-16 59.0 0.2 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 CDO74313.1 - 7.9e-14 51.6 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 CDO74313.1 - 3.1e-08 33.8 0.0 1.3e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain LRR_4 PF12799.7 CDO74314.1 - 0.0024 18.3 0.5 28 5.3 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDO74314.1 - 0.35 11.6 1.5 31 5.6 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich Repeat Retrotran_gag_2 PF14223.6 CDO74315.1 - 2.4e-12 46.7 0.0 2.7e-11 43.3 0.0 2.0 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO74315.1 - 0.00028 20.7 0.2 0.00067 19.5 0.2 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain Ribosomal_S25 PF03297.15 CDO74315.1 - 0.47 10.7 2.5 1.1 9.5 2.5 1.5 1 0 0 1 1 1 0 S25 ribosomal protein DUF4219 PF13961.6 CDO74315.1 - 0.58 9.9 4.2 6.6 6.5 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) APC_u13 PF16634.5 CDO74316.1 - 3.8 7.5 6.5 6.9 6.7 4.1 2.3 1 1 1 2 2 2 0 Unstructured region on APC between APC_crr and SAMP Ribosomal_S5 PF00333.20 CDO74317.1 - 9.9e-29 99.1 0.9 9.9e-29 99.1 0.9 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CDO74317.1 - 1.5e-23 82.0 0.0 2.6e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain RNA_pol PF00940.19 CDO74317.1 - 0.22 10.3 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase FoP_duplication PF13865.6 CDO74317.1 - 7.8 7.1 8.9 16 6.1 8.9 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Fungal_trans PF04082.18 CDO74319.1 - 3.2e-22 78.8 0.4 1.6e-18 66.7 0.0 2.9 2 1 1 3 3 3 2 Fungal specific transcription factor domain Glyco_hydro_10 PF00331.20 CDO74320.1 - 1e-71 241.7 0.0 2.2e-65 220.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 Arginase PF00491.21 CDO74321.1 - 3.8e-71 239.9 0.0 4.6e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family FKBP_N_2 PF18023.1 CDO74321.1 - 0.2 11.8 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 BDBT FKBP like N-terminal Asp PF00026.23 CDO74322.1 - 1.1e-27 97.3 1.3 1.3e-27 97.1 1.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF2013 PF09431.10 CDO74325.1 - 3.8e-43 147.0 1.9 7.5e-43 146.0 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) KDZ PF18758.1 CDO74326.1 - 4.3e-47 160.6 0.0 7.6e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 CDO74326.1 - 7.6e-36 122.5 0.0 3.9e-35 120.3 0.0 2.1 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 CDO74326.1 - 1.6e-07 31.5 0.0 4.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 CDO74326.1 - 0.013 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 CDO74326.1 - 0.12 12.6 4.1 0.26 11.5 4.1 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-UBR PF02207.20 CDO74326.1 - 0.42 10.8 4.2 0.52 10.5 2.8 1.8 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) CEBP_ZZ PF16366.5 CDO74326.1 - 0.53 10.6 4.2 1.2 9.5 4.2 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Cauli_VI PF01693.16 CDO74327.1 - 4.8e-07 30.0 1.1 2.7e-05 24.4 0.2 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin Dpoe2NT PF12213.8 CDO74328.1 - 0.18 12.1 0.1 0.59 10.5 0.0 1.8 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal FlgI PF02119.16 CDO74328.1 - 0.22 10.4 0.2 0.33 9.8 0.2 1.2 1 0 0 1 1 1 0 Flagellar P-ring protein ABC_tran PF00005.27 CDO74329.1 - 7.7e-47 159.2 0.0 8e-28 97.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CDO74329.1 - 1.7e-43 149.2 22.8 1.7e-24 86.9 9.7 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CDO74329.1 - 2e-10 40.5 6.0 0.024 14.0 1.3 4.7 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDO74329.1 - 4.6e-09 36.5 1.3 0.016 15.0 0.0 4.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDO74329.1 - 9.9e-08 32.7 2.7 0.00041 20.9 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 CDO74329.1 - 5.3e-06 26.2 0.2 0.016 14.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CDO74329.1 - 2.3e-05 24.0 4.9 0.07 12.9 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDO74329.1 - 3.2e-05 24.0 0.1 0.097 12.8 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 CDO74329.1 - 5.8e-05 23.5 3.8 0.24 11.8 0.4 3.2 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 CDO74329.1 - 7.6e-05 23.0 0.1 0.92 9.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CDO74329.1 - 0.00012 22.0 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 CDO74329.1 - 0.00017 20.8 0.1 0.33 10.0 0.0 2.7 3 0 0 3 3 2 2 Type II/IV secretion system protein DUF87 PF01935.17 CDO74329.1 - 0.00032 20.9 0.7 0.015 15.4 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 CDO74329.1 - 0.0014 18.4 0.3 2.5 7.8 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 CDO74329.1 - 0.0034 16.8 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_7 PF12775.7 CDO74329.1 - 0.01 15.4 0.1 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 CDO74329.1 - 0.011 15.5 0.1 3.8 7.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDO74329.1 - 0.017 15.7 0.0 5.6 7.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 CDO74329.1 - 0.025 14.3 0.0 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 CDO74329.1 - 0.034 13.0 0.1 1.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.14 CDO74329.1 - 0.04 13.9 0.3 23 5.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 CDO74329.1 - 0.05 12.6 0.1 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 CDO74329.1 - 0.051 13.4 0.9 0.18 11.6 0.0 2.3 4 0 0 4 4 2 0 AAA domain PduV-EutP PF10662.9 CDO74329.1 - 0.055 13.2 0.6 5 6.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Med13_C PF06333.12 CDO74329.1 - 0.059 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain ResIII PF04851.15 CDO74329.1 - 0.07 13.1 0.0 4.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 CDO74329.1 - 0.086 12.8 0.2 0.68 9.8 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_15 PF13175.6 CDO74329.1 - 0.095 12.4 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 CDO74329.1 - 0.095 12.9 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CDO74329.1 - 0.12 11.8 0.1 10 5.5 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein TrwB_AAD_bind PF10412.9 CDO74329.1 - 0.12 11.2 0.8 4.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.6 CDO74329.1 - 0.18 11.8 0.0 11 6.1 0.0 3.4 4 0 0 4 4 4 0 AAA domain cobW PF02492.19 CDO74329.1 - 0.18 11.4 2.7 2.9 7.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 CDO74329.1 - 0.19 11.1 2.2 6.1 6.2 0.1 3.0 4 0 0 4 4 3 0 Poxvirus A32 protein DUF2975 PF11188.8 CDO74329.1 - 1.1 9.2 8.9 0.7 9.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Herpes_capsid PF06112.11 CDO74329.1 - 4.4 7.3 12.3 9.8 6.2 12.3 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein BTB PF00651.31 CDO74330.1 - 9.8e-05 22.6 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 CDO74331.1 - 0.0089 16.2 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Proteasome PF00227.26 CDO74332.1 - 1.9e-39 135.1 0.0 2.3e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit BTB PF00651.31 CDO74333.1 - 0.021 15.1 0.0 0.033 14.4 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain ANAPC4_WD40 PF12894.7 CDO74334.1 - 6.9e-21 74.4 3.2 2.8e-08 33.9 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDO74334.1 - 6.1e-17 61.7 12.8 2.4e-05 25.0 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 CDO74334.1 - 1.7e-08 34.6 0.1 2.5e-05 24.3 0.0 3.7 1 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDO74334.1 - 0.00019 20.5 0.1 0.027 13.4 0.0 3.0 2 2 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein FlgM PF04316.13 CDO74335.1 - 0.066 13.6 2.7 0.47 10.8 0.1 2.6 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM HMA PF00403.26 CDO74336.1 - 0.074 13.5 0.3 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 Heavy-metal-associated domain BTB PF00651.31 CDO74337.1 - 0.0046 17.2 0.0 0.0081 16.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF775 PF05603.12 CDO74338.1 - 5.3e-54 182.8 0.0 6.2e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) WD40 PF00400.32 CDO74341.1 - 1.6e-26 92.0 12.2 6.8e-06 26.7 0.3 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO74341.1 - 0.00022 21.4 0.3 0.017 15.4 0.0 3.4 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDO74341.1 - 0.0062 15.9 0.0 0.42 9.9 0.0 2.5 3 0 0 3 3 3 1 WD40-like domain RAB3GAP2_N PF14655.6 CDO74341.1 - 0.033 13.4 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus VCX_VCY PF15231.6 CDO74341.1 - 1.6 9.4 8.9 5.7 7.6 5.6 2.4 2 0 0 2 2 2 0 Variable charge X/Y family Aminotran_1_2 PF00155.21 CDO74342.1 - 4.6e-38 131.3 0.0 6.8e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CDO74342.1 - 0.22 10.8 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase HMGL-like PF00682.19 CDO74344.1 - 2.4e-43 148.6 0.0 3.1e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Gelsolin PF00626.22 CDO74347.1 - 0.0018 18.1 0.1 0.33 10.9 0.0 3.0 3 0 0 3 3 3 2 Gelsolin repeat Glyco_hydro_16 PF00722.21 CDO74348.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 FAD_binding_3 PF01494.19 CDO74349.1 - 1.8e-31 109.7 0.0 2.5e-31 109.2 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 CDO74349.1 - 0.00016 21.4 0.1 0.46 10.0 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDO74349.1 - 0.00025 20.4 0.1 0.4 9.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDO74349.1 - 0.0079 16.7 0.0 7.8 7.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO74349.1 - 0.063 13.5 0.1 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 CDO74349.1 - 0.076 12.0 0.0 0.58 9.2 0.0 2.1 1 1 0 1 1 1 0 Squalene epoxidase Pro-kuma_activ PF09286.11 CDO74350.1 - 5.6e-36 124.0 0.1 1.4e-34 119.5 0.0 2.4 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO74350.1 - 1.5e-05 24.4 4.5 2.5e-05 23.7 4.5 1.3 1 0 0 1 1 1 1 Subtilase family RVT_2 PF07727.14 CDO74351.1 - 6.1e-80 268.4 0.1 8.4e-80 267.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) P34-Arc PF04045.14 CDO74354.1 - 1.3e-105 352.4 0.1 1.6e-105 352.2 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Homeodomain PF00046.29 CDO74355.1 - 1.4e-19 69.7 3.0 2.3e-19 69.0 3.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDO74355.1 - 0.061 13.2 0.6 0.13 12.2 0.6 1.5 1 0 0 1 1 1 0 Homeobox KN domain TEX13 PF15186.6 CDO74355.1 - 0.32 10.7 2.1 0.52 10.0 2.1 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family RRM_1 PF00076.22 CDO74356.1 - 8.7e-19 67.1 0.1 1.6e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 CDO74356.1 - 7.1e-05 23.4 7.9 0.00014 22.4 7.9 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 CDO74356.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif UbiA PF01040.18 CDO74357.1 - 5.6e-58 196.2 14.7 1e-57 195.3 14.7 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Citrate_synt PF00285.21 CDO74358.1 - 2.2e-92 309.9 0.0 2.7e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Methyltransf_4 PF02390.17 CDO74359.1 - 2.4e-53 180.1 0.0 3.2e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CDO74359.1 - 0.0016 19.1 0.0 0.0054 17.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO74359.1 - 0.021 15.5 0.0 0.084 13.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CDO74359.1 - 0.12 11.9 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.12 CDO74359.1 - 0.16 12.8 0.0 0.51 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain RNase_PH PF01138.21 CDO74360.1 - 7.1e-36 123.6 0.1 1.5e-35 122.6 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDO74360.1 - 0.00021 21.3 0.0 0.00045 20.2 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Tautomerase PF01361.21 CDO74360.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Tautomerase enzyme NAPRTase PF04095.16 CDO74361.1 - 1.2e-64 218.3 0.0 1.6e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CDO74361.1 - 3.5e-22 79.1 3.1 1.7e-15 57.5 1.5 2.4 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain SH3_1 PF00018.28 CDO74362.1 - 2.8e-13 49.3 0.1 4e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDO74362.1 - 7.9e-13 48.0 0.1 1.3e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDO74362.1 - 4.3e-11 42.3 0.0 8.3e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 CDO74362.1 - 4.7 7.2 7.4 9.7 6.1 7.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Voldacs PF03517.13 CDO74363.1 - 2.3e-25 89.3 0.1 2.3e-25 89.3 0.1 2.2 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling zf-C2H2_assoc3 PF16637.5 CDO74363.1 - 0.28 11.4 5.5 0.58 10.4 3.7 2.3 2 1 0 2 2 2 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz ANAPC4_WD40 PF12894.7 CDO74364.1 - 0.0058 16.9 0.0 0.94 9.8 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Syntaxin-6_N PF09177.11 CDO74364.1 - 0.2 12.3 1.5 1.3 9.6 1.4 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FliJ PF02050.16 CDO74364.1 - 0.27 11.4 6.0 0.056 13.7 0.8 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein FapA PF03961.13 CDO74364.1 - 1.6 7.2 4.3 3.5 6.1 3.8 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A Nop14 PF04147.12 CDO74364.1 - 5.7 5.0 31.7 1.3 7.1 5.7 2.4 2 0 0 2 2 2 0 Nop14-like family Plasmodium_Vir PF05795.11 CDO74365.1 - 1.5 8.2 2.7 2.3 7.5 2.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein COX6B PF02297.17 CDO74366.1 - 4e-16 59.0 5.7 4e-16 59.0 5.7 1.9 1 1 1 2 2 2 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 CDO74366.1 - 0.025 14.6 1.8 0.043 13.8 1.8 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Prp18 PF02840.15 CDO74367.1 - 7e-59 198.0 0.5 7e-59 198.0 0.5 2.4 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.11 CDO74367.1 - 1.6e-11 43.6 5.5 1.6e-11 43.6 5.5 2.3 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like PTPRCAP PF15713.5 CDO74367.1 - 7.7 6.8 17.0 8.3 6.7 2.9 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Retrotrans_gag PF03732.17 CDO74368.1 - 1.9e-11 44.0 0.1 6.9e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO74368.1 - 3.4e-09 36.6 0.0 7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) RVP_2 PF08284.11 CDO74369.1 - 8.8e-08 32.0 0.0 1.5e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDO74369.1 - 4.1e-07 30.5 0.0 8.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDO74369.1 - 0.00016 22.2 0.0 0.00032 21.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 CDO74369.1 - 0.0005 19.7 0.0 0.0008 19.0 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase RT_RNaseH PF17917.1 CDO74370.1 - 5.7e-35 119.8 0.1 1.1e-34 118.8 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO74370.1 - 4.7e-30 103.6 0.0 1.3e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO74370.1 - 2.2e-21 76.4 0.0 4.3e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1474 PF07342.11 CDO74370.1 - 0.098 13.2 0.2 0.3 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) rve PF00665.26 CDO74371.1 - 9e-09 35.6 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_2 PF02914.15 CDO74371.1 - 0.021 14.6 0.0 1.1 8.9 0.0 2.2 1 1 1 2 2 2 0 Bacteriophage Mu transposase COMP PF11598.8 CDO74371.1 - 0.23 12.0 1.0 0.42 11.1 1.0 1.4 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein APH PF01636.23 CDO74372.1 - 0.0003 20.8 0.1 0.00041 20.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HET PF06985.11 CDO74373.1 - 2.3e-11 44.2 9.0 4.6e-09 36.8 2.9 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) 7tm_7 PF08395.12 CDO74373.1 - 0.22 10.7 0.7 0.38 9.9 0.7 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor Lectin_leg-like PF03388.13 CDO74374.1 - 4.3e-65 219.3 0.1 5.5e-65 218.9 0.1 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 CDO74374.1 - 9.3e-06 25.4 0.0 0.031 13.8 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain adh_short PF00106.25 CDO74375.1 - 2.4e-28 98.9 0.0 5.1e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO74375.1 - 2.1e-19 70.0 0.0 4.3e-19 69.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO74375.1 - 1.4e-08 34.8 0.0 1.8e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDO74375.1 - 0.00035 20.5 0.0 0.00078 19.4 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 CDO74375.1 - 0.026 14.5 0.1 0.039 13.9 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 CDO74375.1 - 0.029 13.9 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CDO74376.1 - 1.3e-32 112.8 0.0 1.6e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO74376.1 - 5.8e-21 75.1 0.0 7.4e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO74376.1 - 2.5e-09 37.3 0.0 3.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CDO74376.1 - 1.2e-06 28.6 0.1 1.8e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CDO74376.1 - 0.00018 21.0 0.1 0.0003 20.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDO74376.1 - 0.0074 15.4 0.0 0.011 14.9 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DUF3025 PF11227.8 CDO74376.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Fe_hyd_lg_C PF02906.14 CDO74376.1 - 0.21 11.2 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Pkinase_fungal PF17667.1 CDO74377.1 - 4.3e-20 71.9 0.0 6.1e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO74378.1 - 3e-41 141.6 0.1 1.3e-38 132.9 0.0 2.6 2 1 0 2 2 2 1 Fungal protein kinase Pan_kinase PF03309.14 CDO74378.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Type III pantothenate kinase HNH_2 PF13391.6 CDO74379.1 - 5.8e-05 23.1 0.0 0.00017 21.6 0.0 1.7 1 1 0 1 1 1 1 HNH endonuclease EF_assoc_2 PF08356.12 CDO74379.1 - 0.067 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 EF hand associated Pkinase_fungal PF17667.1 CDO74380.1 - 0.0011 17.8 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RAP1 PF07218.11 CDO74380.1 - 4.2 5.5 4.7 5.3 5.2 4.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ETF_QO PF05187.13 CDO74381.1 - 0.0002 21.4 0.0 0.00043 20.4 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Acyl-ACP_TE PF01643.17 CDO74381.1 - 0.048 12.9 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase MULE PF10551.9 CDO74382.1 - 3.5e-14 53.0 0.0 6.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Glyco_trans_4_3 PF12000.8 CDO74382.1 - 0.042 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 4 group Cytochrom_c3_2 PF14537.6 CDO74382.1 - 3.8 8.0 9.0 0.66 10.5 4.5 2.0 2 0 0 2 2 2 0 Cytochrome c3 KDZ PF18758.1 CDO74385.1 - 1.7e-30 106.3 0.4 4.4e-30 105.0 0.2 1.8 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase PHD PF00628.29 CDO74387.1 - 0.0031 17.4 4.8 0.0081 16.0 1.8 2.4 2 0 0 2 2 2 1 PHD-finger FOXP-CC PF16159.5 CDO74388.1 - 0.13 12.9 0.6 0.52 11.0 0.1 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain Pkinase PF00069.25 CDO74389.1 - 7.9e-21 74.6 0.0 9.4e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO74389.1 - 7.5e-08 32.0 0.0 8.8e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 CDO74390.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 CDO74390.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box domain Tetraspanin PF00335.20 CDO74391.1 - 0.00012 21.9 7.6 0.00012 21.9 7.6 2.0 1 1 1 2 2 2 1 Tetraspanin family PhoR PF11808.8 CDO74391.1 - 0.66 10.4 11.6 11 6.5 5.5 3.4 3 1 0 3 3 3 0 Phosphate regulon sensor protein PhoR SKN1 PF03935.15 CDO74392.1 - 1.6e-185 617.3 8.8 1.6e-185 617.3 8.8 1.4 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF4666 PF15697.5 CDO74393.1 - 2.2 9.0 6.9 0.34 11.6 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) NOA36 PF06524.12 CDO74395.1 - 2.4 7.4 13.2 2.9 7.1 13.2 1.2 1 0 0 1 1 1 0 NOA36 protein Ank_4 PF13637.6 CDO74397.1 - 0.0044 17.6 0.0 0.0079 16.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CDO74397.1 - 0.0049 17.3 0.3 0.0049 17.3 0.3 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CDO74397.1 - 0.0059 17.0 0.2 0.04 14.5 0.1 2.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 CDO74397.1 - 0.0062 17.1 0.1 0.009 16.6 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDO74397.1 - 0.02 15.2 0.1 0.068 13.5 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Mating_N PF12731.7 CDO74398.1 - 0.11 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Mating-type protein beta 1 NUDIX PF00293.28 CDO74399.1 - 9.3e-09 35.4 0.2 1.4e-08 34.8 0.2 1.6 1 1 0 1 1 1 1 NUDIX domain Cupin_5 PF06172.11 CDO74400.1 - 4.5e-39 133.8 0.0 5.3e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) RVT_2 PF07727.14 CDO74401.1 - 3.4e-59 200.4 0.0 4.8e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CDO74401.1 - 5e-14 52.1 0.1 9.4e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 CDO74401.1 - 7.7e-13 48.7 0.0 2.5e-12 47.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO74401.1 - 1.2e-07 31.5 0.1 2.9e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.23 CDO74401.1 - 0.0043 17.1 2.8 0.0082 16.2 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle CCDC92 PF14916.6 CDO74401.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function CP12 PF02672.15 CDO74401.1 - 0.15 12.8 0.2 0.98 10.2 0.2 2.4 1 0 0 1 1 1 0 CP12 domain Astro_capsid_p PF12226.8 CDO74402.1 - 0.027 13.6 1.8 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Turkey astrovirus capsid protein FAM176 PF14851.6 CDO74402.1 - 2.2 8.0 6.7 5.7 6.6 1.1 2.2 2 0 0 2 2 2 0 FAM176 family YL1 PF05764.13 CDO74403.1 - 0.085 13.0 13.9 0.1 12.7 13.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 CDO74403.1 - 0.82 7.8 9.2 0.88 7.7 9.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDO74403.1 - 1.7 6.8 6.1 1.6 6.9 6.1 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 CDO74403.1 - 4.1 6.6 11.7 5.5 6.2 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein Enolase_C PF00113.22 CDO74405.1 - 1.7e-144 480.5 0.1 2.3e-144 480.1 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CDO74405.1 - 9.2e-58 194.1 0.0 1.6e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CDO74405.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CDO74405.1 - 0.0013 18.0 0.1 0.0031 16.7 0.1 1.7 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus PAP_assoc PF03828.19 CDO74406.1 - 1.4e-13 50.9 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CDO74406.1 - 2.5e-07 30.9 0.0 4.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CDO74406.1 - 0.075 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Glyco_hydro_20 PF00728.22 CDO74407.1 - 9.5e-25 87.7 0.0 2.6e-22 79.7 0.0 2.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 CDO74407.1 - 2.8e-09 37.8 0.0 1.4e-08 35.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 CDO74407.1 - 0.17 12.5 0.1 0.32 11.7 0.1 1.4 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like Lipase_GDSL_2 PF13472.6 CDO74408.1 - 1.6e-21 77.5 1.6 2.5e-21 76.9 1.6 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CDO74408.1 - 1.8e-06 28.1 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase S4 PF01479.25 CDO74409.1 - 4.1e-11 42.4 1.3 4.1e-11 42.4 1.3 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 CDO74409.1 - 3.1e-06 28.0 0.1 7.2e-06 26.8 0.0 1.7 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 CDO74410.1 - 2.5e-45 152.5 3.9 3.8e-45 151.9 3.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_replicase_B PF03431.13 CDO74410.1 - 0.017 13.6 0.2 0.019 13.4 0.2 1.0 1 0 0 1 1 1 0 RNA replicase, beta-chain AGT PF11440.8 CDO74410.1 - 0.069 12.2 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase DUF3613 PF12266.8 CDO74412.1 - 0.07 12.9 1.1 0.12 12.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) TIP49 PF06068.13 CDO74413.1 - 1.1e-158 528.0 0.1 1.4e-158 527.6 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CDO74413.1 - 6e-21 74.3 1.7 3.4e-20 72.0 1.8 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 CDO74413.1 - 5.2e-09 36.6 0.2 1.2e-05 25.7 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CDO74413.1 - 4.5e-06 26.5 0.2 0.0081 15.9 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDO74413.1 - 0.00013 22.4 0.3 0.00053 20.4 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 CDO74413.1 - 0.00013 21.4 0.3 0.00026 20.4 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 CDO74413.1 - 0.00065 19.1 2.1 0.018 14.4 0.3 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CDO74413.1 - 0.0024 17.5 0.9 0.093 12.3 0.1 2.7 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CDO74413.1 - 0.0084 16.4 0.0 0.28 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CDO74413.1 - 0.016 15.2 0.2 6.8 6.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TFIID_20kDa PF03847.13 CDO74413.1 - 0.03 14.8 0.3 0.08 13.4 0.3 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A AAA_19 PF13245.6 CDO74413.1 - 0.084 13.2 3.4 0.32 11.3 1.2 2.7 2 1 0 2 2 2 0 AAA domain Ribosomal_L2_C PF03947.18 CDO74414.1 - 2.4e-53 179.6 2.0 4.3e-53 178.8 2.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CDO74414.1 - 5e-25 87.3 0.1 1.1e-24 86.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribophorin_I PF04597.14 CDO74415.1 - 0.04 13.1 0.0 0.088 12.0 0.0 1.5 2 0 0 2 2 2 0 Ribophorin I Methyltransf_16 PF10294.9 CDO74416.1 - 1e-18 67.7 0.0 1.5e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 CDO74416.1 - 1.1e-07 32.4 0.0 1.1e-06 29.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO74416.1 - 1.9e-07 31.7 0.0 3.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDO74416.1 - 8.8e-07 28.6 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CDO74416.1 - 7.5e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO74416.1 - 0.00014 22.4 0.0 0.00046 20.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO74416.1 - 0.00063 19.6 0.0 0.00096 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CDO74416.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CDO74416.1 - 0.0011 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 CDO74416.1 - 0.0052 16.6 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF938 PF06080.12 CDO74416.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Homeodomain PF00046.29 CDO74417.1 - 2.4e-14 52.9 4.1 4.8e-14 52.0 4.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CDO74417.1 - 0.0014 18.5 0.1 0.0031 17.4 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain GvpL_GvpF PF06386.11 CDO74418.1 - 0.087 12.7 4.2 0.1 12.5 4.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Histone PF00125.24 CDO74419.1 - 4.1e-46 156.6 1.4 4.1e-46 156.6 1.4 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CDO74419.1 - 3.8e-05 24.0 0.1 6.2e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CDO74419.1 - 0.00015 21.8 0.1 0.00015 21.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CDO74419.1 - 0.00097 19.4 1.0 0.0021 18.3 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CDO74419.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated FlxA PF14282.6 CDO74420.1 - 0.0044 17.0 0.4 0.0044 17.0 0.4 1.8 2 0 0 2 2 2 1 FlxA-like protein PsaL PF02605.15 CDO74420.1 - 0.085 12.5 0.5 0.14 11.8 0.5 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI Spc7 PF08317.11 CDO74420.1 - 0.17 10.7 2.2 0.25 10.2 2.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HemX PF04375.14 CDO74420.1 - 0.18 11.1 1.6 0.29 10.4 1.6 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Atg14 PF10186.9 CDO74420.1 - 0.26 10.3 2.3 0.49 9.4 2.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 CDO74420.1 - 0.59 10.7 2.7 2.2 8.9 2.8 1.8 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Mid2 PF04478.12 CDO74421.1 - 5.1e-05 23.2 1.3 5.1e-05 23.2 1.3 1.9 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor LapA_dom PF06305.11 CDO74421.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM154 PF15102.6 CDO74421.1 - 0.019 14.9 0.0 0.019 14.9 0.0 2.3 2 1 1 3 3 3 0 TMEM154 protein family Orthoreo_P10 PF07204.11 CDO74421.1 - 0.021 14.8 0.2 0.042 13.8 0.2 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 LST1 PF05083.13 CDO74421.1 - 0.035 14.4 0.1 0.068 13.5 0.1 1.4 1 0 0 1 1 1 0 LST-1 protein Herpes_gE PF02480.16 CDO74421.1 - 0.086 11.6 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E WD40_alt PF14077.6 CDO74422.1 - 0.13 12.2 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif SKG6 PF08693.10 CDO74422.1 - 0.65 9.4 4.7 1.8 8.0 4.7 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.6 CDO74422.1 - 2.1 8.6 7.7 28 4.9 6.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator CBM_21 PF03370.13 CDO74423.1 - 3.1e-25 88.6 0.0 5.1e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CDO74423.1 - 2.1e-07 31.4 0.0 4.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Roughex PF06020.11 CDO74424.1 - 0.067 12.3 1.2 0.11 11.5 1.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ntox34 PF15606.6 CDO74424.1 - 0.17 12.0 1.1 0.44 10.7 0.3 2.1 2 0 0 2 2 2 0 Bacterial toxin 34 MFMR_assoc PF16596.5 CDO74424.1 - 0.48 10.9 5.9 11 6.5 0.5 2.4 2 0 0 2 2 2 0 Disordered region downstream of MFMR KDZ PF18758.1 CDO74426.1 - 1.7e-85 286.2 0.0 2.8e-85 285.5 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Redoxin PF08534.10 CDO74427.1 - 0.0021 17.8 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Redoxin HMG_box_2 PF09011.10 CDO74427.1 - 0.018 15.6 0.4 0.059 14.0 0.2 1.9 2 0 0 2 2 2 0 HMG-box domain HMG_box PF00505.19 CDO74427.1 - 0.095 13.1 0.3 0.25 11.8 0.3 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box Peptidase_S41 PF03572.18 CDO74428.1 - 0.00092 18.8 0.0 0.0027 17.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 Pkinase_fungal PF17667.1 CDO74432.1 - 1.8e-10 40.2 0.0 4.9e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO74433.1 - 1.2e-58 198.9 0.0 2.6e-58 197.7 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase SAP PF02037.27 CDO74435.1 - 7.9e-08 31.9 0.8 2.1e-07 30.6 0.5 1.8 2 0 0 2 2 2 1 SAP domain Med7 PF05983.11 CDO74436.1 - 1.3e-42 146.1 0.3 1.5e-42 145.9 0.3 1.0 1 0 0 1 1 1 1 MED7 protein RRM_1 PF00076.22 CDO74438.1 - 1.5e-08 34.3 0.4 0.0025 17.6 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4603 PF15376.6 CDO74438.1 - 0.21 8.9 20.9 0.42 7.9 20.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) XPG_N PF00752.17 CDO74439.1 - 6.5e-33 113.2 0.0 1.3e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CDO74439.1 - 3e-30 104.4 0.0 8e-30 103.1 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CDO74439.1 - 9.2e-07 29.4 0.1 2.6e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 CDO74439.1 - 0.055 14.1 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain zf-C2H2_4 PF13894.6 CDO74440.1 - 0.24 12.4 0.8 0.57 11.2 0.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger TssN PF17555.2 CDO74441.1 - 0.043 13.2 0.6 0.043 13.2 0.6 2.3 2 1 0 2 2 2 0 Type VI secretion system, TssN Na_H_Exchanger PF00999.21 CDO74442.1 - 9.1e-60 202.4 27.1 2.5e-59 201.0 27.1 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF883 PF05957.13 CDO74442.1 - 0.1 13.2 1.7 0.26 11.9 1.4 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Mitofilin PF09731.9 CDO74442.1 - 4.2 6.1 9.5 5.8 5.6 9.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein p450 PF00067.22 CDO74443.1 - 9.7e-46 156.5 0.1 4.3e-39 134.5 0.0 2.8 2 1 1 3 3 3 2 Cytochrome P450 DSPc PF00782.20 CDO74443.1 - 9.1e-17 61.1 0.0 1.8e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Amino_oxidase PF01593.24 CDO74443.1 - 0.0091 15.3 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Y_phosphatase PF00102.27 CDO74443.1 - 0.018 14.6 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Myotub-related PF06602.14 CDO74443.1 - 0.03 13.3 0.1 0.052 12.5 0.1 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF1617 PF07761.12 CDO74443.1 - 0.18 11.9 0.0 0.47 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1617) FlgN PF05130.12 CDO74444.1 - 0.37 11.3 1.7 0.62 10.6 0.2 2.0 2 1 0 2 2 2 0 FlgN protein CAML PF14963.6 CDO74445.1 - 0.1 12.7 0.6 0.13 12.3 0.0 1.5 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Pkinase_fungal PF17667.1 CDO74446.1 - 1.2e-06 27.6 0.0 1.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CDO74446.1 - 6.6e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO74446.1 - 0.006 15.9 0.1 0.017 14.4 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Amidohydro_1 PF01979.20 CDO74447.1 - 2.3e-11 43.6 0.0 3.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CDO74447.1 - 2.6e-07 30.5 0.1 7.2e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family Ank PF00023.30 CDO74448.1 - 0.00021 21.6 0.0 0.00053 20.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 CDO74448.1 - 0.00074 20.1 0.0 0.0022 18.5 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDO74448.1 - 0.0046 17.3 0.0 0.033 14.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CDO74448.1 - 0.013 16.0 0.0 0.032 14.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Sybindin PF04099.12 CDO74450.1 - 1.5e-21 76.8 0.0 1.9e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family HECW1_helix PF18436.1 CDO74450.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 MFS_1 PF07690.16 CDO74451.1 - 1.1e-24 87.1 49.1 2.8e-16 59.4 23.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 CDO74451.1 - 1.9e-08 33.3 22.9 6.4e-08 31.5 22.9 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SNF2_N PF00176.23 CDO74452.1 - 1.9e-59 201.2 0.0 3.2e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDO74452.1 - 1.2e-18 67.5 0.0 5.9e-18 65.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO74452.1 - 6.7e-10 39.2 0.0 3.8e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_3 PF12836.7 CDO74452.1 - 5.6e-06 26.5 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif ERCC3_RAD25_C PF16203.5 CDO74452.1 - 4.8e-05 22.7 0.3 0.00011 21.5 0.3 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF3552 PF12072.8 CDO74452.1 - 0.11 11.8 5.0 0.056 12.8 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Mito_carr PF00153.27 CDO74453.1 - 9.4e-10 38.3 0.0 1.8e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial carrier protein PspB PF06667.12 CDO74454.1 - 0.21 11.6 0.0 0.45 10.6 0.0 1.4 1 0 0 1 1 1 0 Phage shock protein B zf-CCCH PF00642.24 CDO74455.1 - 2.7e-14 52.7 16.0 3.8e-07 29.9 2.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDO74455.1 - 0.00094 19.9 2.3 1.3 9.7 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 CDO74455.1 - 0.003 17.8 3.2 0.047 13.9 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 CDO74455.1 - 0.0065 16.5 3.3 0.0065 16.5 3.3 2.5 2 0 0 2 2 2 1 Zinc finger domain RRM_1 PF00076.22 CDO74455.1 - 0.011 15.6 0.0 0.024 14.4 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruB_C PF09142.11 CDO74455.1 - 0.063 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal TPR_1 PF00515.28 CDO74456.1 - 1.3e-26 91.3 19.3 0.00044 20.0 0.1 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 CDO74456.1 - 8.8e-23 78.6 19.3 0.00013 21.9 0.0 7.2 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 CDO74456.1 - 5.5e-19 66.7 23.3 0.00059 19.8 0.1 7.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 CDO74456.1 - 3.1e-16 58.7 17.4 0.0071 17.1 0.1 7.9 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 CDO74456.1 - 7e-14 51.2 4.1 1.9e-06 27.4 0.8 5.1 3 2 2 5 5 5 3 TPR repeat TPR_12 PF13424.6 CDO74456.1 - 1.8e-13 50.5 22.5 0.017 15.4 1.0 6.5 3 2 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 CDO74456.1 - 9.3e-13 48.6 14.0 1.3e-05 25.7 1.7 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO74456.1 - 1.9e-12 46.3 12.4 0.0034 17.3 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDO74456.1 - 7.9e-10 39.1 13.6 0.00067 20.1 0.4 6.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDO74456.1 - 6.2e-08 32.5 4.2 0.0085 16.4 0.8 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDO74456.1 - 3e-06 26.7 7.1 0.022 14.0 3.5 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDO74456.1 - 3.5e-05 23.5 16.3 0.0087 15.9 0.6 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDO74456.1 - 0.0005 20.2 15.7 0.00094 19.3 0.5 5.1 3 1 3 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.10 CDO74456.1 - 0.0053 15.8 0.2 0.023 13.7 0.0 2.0 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CDO74456.1 - 0.0064 17.1 20.6 0.57 10.9 0.4 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 CDO74456.1 - 0.038 14.6 6.7 0.64 10.8 0.1 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO74456.1 - 0.043 14.1 17.6 0.67 10.2 1.0 4.2 1 1 3 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 CDO74456.1 - 0.061 13.7 0.5 20 5.6 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 CDO74456.1 - 0.17 11.6 7.2 5.8 6.6 0.2 3.5 1 1 1 2 2 2 0 26S proteasome subunit RPN7 BTAD PF03704.17 CDO74456.1 - 5.1 7.5 14.8 2.5 8.6 2.8 3.1 2 1 0 2 2 2 0 Bacterial transcriptional activator domain GLTSCR1 PF15249.6 CDO74457.1 - 1.8e-25 89.3 0.6 1.8e-25 89.3 0.6 1.7 2 0 0 2 2 2 1 Conserved region of unknown function on GLTSCR protein SOGA PF11365.8 CDO74457.1 - 5.2 8.3 7.6 5.4 8.2 1.8 3.1 3 1 1 4 4 4 0 Protein SOGA F-box PF00646.33 CDO74458.1 - 0.00064 19.5 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO74458.1 - 0.0046 16.8 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 CDO74459.1 - 1.6e-16 60.2 0.0 3.1e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 CDO74459.1 - 0.016 15.4 1.0 0.032 14.4 0.1 1.9 2 0 0 2 2 2 0 Gal4-like dimerisation domain DUF1674 PF07896.12 CDO74460.1 - 1.1e-14 54.6 2.7 1.1e-14 54.6 2.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Hemerythrin PF01814.23 CDO74461.1 - 2.5e-11 44.3 2.5 3.2e-11 44.0 2.5 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_RpbA PF10789.9 CDO74461.1 - 0.0089 16.1 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Phage RNA polymerase binding, RpbA Glyco_hyd_65N_2 PF14498.6 CDO74461.1 - 0.017 15.0 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain BAR PF03114.18 CDO74462.1 - 4.8e-50 170.4 0.5 5.7e-50 170.2 0.5 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 CDO74462.1 - 0.00034 20.3 1.3 0.0041 16.7 0.2 2.1 2 0 0 2 2 2 1 Arfaptin-like domain HOOK PF05622.12 CDO74462.1 - 0.13 10.4 2.4 0.18 9.9 2.4 1.4 1 1 0 1 1 1 0 HOOK protein Flagellin_N PF00669.20 CDO74462.1 - 0.15 12.2 1.1 1.9 8.6 0.2 2.6 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region F-box-like PF12937.7 CDO74464.1 - 1.8e-07 30.9 0.0 4.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO74464.1 - 0.0043 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain EMP70 PF02990.16 CDO74465.1 - 6e-162 539.9 4.1 1.1e-127 426.8 0.0 2.3 2 1 1 3 3 3 2 Endomembrane protein 70 tRNA-synt_1b PF00579.25 CDO74466.1 - 3.3e-59 200.6 0.0 4.4e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 CDO74466.1 - 0.0023 17.6 0.0 0.0058 16.3 0.0 1.7 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 CDO74466.1 - 0.075 12.8 0.0 7 6.5 0.0 2.4 1 1 1 2 2 2 0 Tyrosyl-tRNA synthetase C-terminal domain KptA_kDCL PF18176.1 CDO74466.1 - 0.088 12.7 0.0 2.4 8.0 0.1 2.4 2 1 0 2 2 2 0 KptA in kinetoplastid DICER domain TGT PF01702.18 CDO74467.1 - 7.7e-72 242.3 0.0 8.7e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DEAD PF00270.29 CDO74468.1 - 9e-40 136.3 0.0 7.7e-39 133.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO74468.1 - 6.7e-25 87.6 0.2 4.2e-24 85.0 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CDO74468.1 - 7.1e-22 77.4 5.7 3e-21 75.4 5.7 2.2 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 CDO74468.1 - 0.00042 19.6 0.0 0.0009 18.5 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Clr5 PF14420.6 CDO74468.1 - 0.026 14.7 0.4 0.075 13.3 0.4 1.7 1 0 0 1 1 1 0 Clr5 domain MFS_1 PF07690.16 CDO74469.1 - 8.2e-31 107.2 32.5 8.2e-31 107.2 32.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Importin_rep PF18773.1 CDO74470.1 - 0.039 13.7 0.4 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Importin 13 repeat Pap_E4 PF02711.14 CDO74470.1 - 5 8.2 6.5 9.2 7.3 2.2 2.7 2 1 0 2 2 2 0 E4 protein DDE_Tnp_4 PF13359.6 CDO74471.1 - 8.7e-18 64.5 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO74471.1 - 2.6e-05 23.9 0.0 6.4e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO74471.1 - 0.0042 16.7 0.1 0.0072 16.0 0.1 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO74471.1 - 0.031 14.6 0.1 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain ABC_membrane PF00664.23 CDO74472.1 - 9.9e-69 232.0 25.4 1.6e-35 123.1 12.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDO74472.1 - 2.1e-53 180.5 0.0 3.1e-31 108.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDO74472.1 - 2.8e-09 36.7 2.1 0.0099 15.3 0.1 3.6 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDO74472.1 - 1.8e-06 27.6 0.9 0.048 13.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CDO74472.1 - 5.8e-06 26.3 0.8 0.066 13.0 0.0 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CDO74472.1 - 1.8e-05 24.8 2.8 0.055 13.6 0.1 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CDO74472.1 - 0.00012 22.7 3.8 0.22 12.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 CDO74472.1 - 0.00027 20.9 1.4 0.23 11.3 0.1 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 CDO74472.1 - 0.00045 20.6 0.3 1.3 9.4 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 CDO74472.1 - 0.00097 18.9 0.0 0.5 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CDO74472.1 - 0.0074 16.0 1.7 2.3 7.9 0.1 2.7 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 CDO74472.1 - 0.0096 15.4 0.5 3.5 7.1 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 CDO74472.1 - 0.012 14.5 0.1 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 CDO74472.1 - 0.016 15.0 0.9 14 5.4 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 CDO74472.1 - 0.018 14.6 0.1 0.31 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CDO74472.1 - 0.036 14.3 2.3 2.1 8.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 CDO74472.1 - 0.048 13.7 1.7 0.41 10.7 0.2 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 CDO74472.1 - 0.083 12.5 0.0 6.2 6.4 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 CDO74472.1 - 0.096 12.7 3.0 5.5 7.0 0.1 2.9 3 0 0 3 3 3 0 Dynamin family Roc PF08477.13 CDO74472.1 - 0.14 12.4 0.9 9.6 6.5 0.1 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CDO74472.1 - 0.16 11.1 0.2 10 5.2 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 CDO74472.1 - 0.21 12.0 0.0 62 4.0 0.0 3.1 3 0 0 3 3 3 0 RNA helicase Zeta_toxin PF06414.12 CDO74472.1 - 0.24 10.6 0.9 6.8 5.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 CDO74472.1 - 0.7 9.2 2.3 11 5.2 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 CDO74472.1 - 0.85 9.2 4.4 0.91 9.1 0.0 2.8 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain Transport_MerF PF11431.8 CDO74472.1 - 2.6 8.0 6.3 6.7 6.7 0.2 3.3 3 0 0 3 3 3 0 Membrane transport protein MerF YlaC PF10777.9 CDO74472.1 - 3.4 7.5 4.6 5.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Inner membrane protein YlaC AhpC-TSA_2 PF13911.6 CDO74473.1 - 1.7e-14 53.9 0.0 3.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 CDO74473.1 - 3.8e-07 29.9 0.0 7.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CDO74473.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF3915 PF13054.6 CDO74473.1 - 7.5 6.6 12.7 15 5.6 6.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Aa_trans PF01490.18 CDO74474.1 - 1.9e-82 277.2 34.3 2.2e-82 277.0 34.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YpmT PF17431.2 CDO74474.1 - 0.94 9.6 4.5 0.75 9.9 1.8 2.3 2 0 0 2 2 2 0 Uncharacterized YmpT-like Abhydrolase_3 PF07859.13 CDO74475.1 - 1.2e-19 71.0 0.0 1.9e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDO74475.1 - 8.7e-09 34.7 0.0 1.2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 CDO74475.1 - 0.055 12.3 0.0 0.078 11.8 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family eIF-1a PF01176.19 CDO74476.1 - 3.9e-22 77.8 0.0 5.7e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Metallophos PF00149.28 CDO74477.1 - 3.6e-30 106.0 0.2 4.3e-30 105.7 0.2 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 CDO74477.1 - 0.055 13.1 0.0 0.079 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain VTC PF09359.10 CDO74478.1 - 7.4e-89 297.8 0.4 2e-88 296.3 0.0 1.8 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 CDO74478.1 - 5.3e-19 69.4 16.2 2e-11 44.5 11.4 3.1 1 1 1 2 2 2 2 SPX domain Cwf_Cwc_15 PF04889.12 CDO74478.1 - 3.2 7.4 13.6 6.1 6.5 13.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Gtr1_RagA PF04670.12 CDO74479.1 - 1.3e-32 113.0 1.0 1.4e-32 112.9 1.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Abhydrolase_3 PF07859.13 CDO74480.1 - 2.4e-16 60.3 0.0 3.7e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDO74480.1 - 5.3e-05 22.2 0.0 6.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 CDO74480.1 - 0.00017 22.3 1.3 0.00022 21.9 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO74480.1 - 0.011 15.1 0.0 0.021 14.1 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Ank_4 PF13637.6 CDO74483.1 - 4.9e-05 23.8 0.0 0.02 15.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDO74483.1 - 6.4e-05 23.5 0.0 0.0024 18.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDO74483.1 - 0.0006 20.1 0.0 1.7 9.5 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 CDO74483.1 - 0.005 17.1 0.0 9.1 6.7 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) PKD_channel PF08016.12 CDO74484.1 - 2.7e-06 26.3 17.2 1.3e-05 24.1 1.0 2.1 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 CDO74484.1 - 0.0081 15.4 22.7 0.014 14.6 22.7 1.4 1 0 0 1 1 1 1 Ion transport protein Pkinase PF00069.25 CDO74485.1 - 6.4e-48 163.4 0.0 4.3e-28 98.4 0.0 2.4 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO74485.1 - 2.1e-24 86.2 0.0 2.4e-13 50.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDO74485.1 - 0.0075 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Macro PF01661.21 CDO74486.1 - 2.7e-37 127.4 0.2 3.6e-37 127.0 0.2 1.2 1 0 0 1 1 1 1 Macro domain Sugar_tr PF00083.24 CDO74487.1 - 9.2e-105 351.1 20.9 1.1e-104 350.8 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO74487.1 - 7.4e-27 94.2 55.1 6.7e-22 77.9 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CDO74487.1 - 0.0033 15.9 1.1 0.0033 15.9 1.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.32 CDO74488.1 - 0.099 13.6 0.0 3.2 8.8 0.0 3.3 2 0 0 2 2 2 0 WD domain, G-beta repeat BUD22 PF09073.10 CDO74488.1 - 0.95 8.7 17.3 1.6 8.0 17.3 1.3 1 0 0 1 1 1 0 BUD22 SRP-alpha_N PF04086.13 CDO74488.1 - 6.4 6.6 10.0 12 5.7 10.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NAD_binding_10 PF13460.6 CDO74489.1 - 7.4e-10 39.0 0.1 1.1e-09 38.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CDO74489.1 - 9.7e-09 35.0 0.1 1e-06 28.4 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CDO74489.1 - 3.9e-07 29.9 0.0 5.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 CDO74489.1 - 2.8e-05 24.4 0.1 5.4e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 CDO74489.1 - 4.3e-05 22.8 0.0 9.7e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.20 CDO74489.1 - 4.9e-05 23.4 0.0 0.00027 21.0 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 CDO74489.1 - 0.00038 20.9 0.0 0.00079 19.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CDO74489.1 - 0.0012 19.4 0.0 0.0025 18.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 CDO74489.1 - 0.0016 17.5 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 CDO74489.1 - 0.003 17.8 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.15 CDO74489.1 - 0.0064 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sigma54_activ_2 PF14532.6 CDO74489.1 - 0.055 13.6 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NAD_binding_10 PF13460.6 CDO74490.1 - 1e-09 38.6 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CDO74490.1 - 1.5e-07 31.2 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 CDO74490.1 - 1.5e-05 24.3 0.1 2.5e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.20 CDO74490.1 - 0.00017 21.7 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CDO74490.1 - 0.00038 20.7 0.0 0.00068 19.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 CDO74490.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CDO74490.1 - 0.0067 17.0 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 CDO74490.1 - 0.008 15.7 0.0 0.031 13.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 CDO74490.1 - 0.045 14.0 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.19 CDO74490.1 - 0.062 12.3 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HAD_SAK_1 PF10307.9 CDO74490.1 - 0.085 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins Phage_holin_3_3 PF16083.5 CDO74490.1 - 0.089 12.9 0.3 0.16 12.1 0.3 1.4 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III DXP_reductoisom PF02670.16 CDO74490.1 - 0.13 13.0 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GDP_Man_Dehyd PF16363.5 CDO74490.1 - 0.16 11.3 0.0 6 6.1 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDO74491.1 - 1.1e-10 41.4 0.2 4e-10 39.6 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CDO74491.1 - 7.6e-10 39.0 0.2 1.3e-09 38.2 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CDO74491.1 - 1.6e-07 30.7 0.0 2.4e-07 30.1 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 CDO74491.1 - 2.4e-07 30.5 0.2 3.7e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 CDO74491.1 - 5e-06 26.8 0.1 8.6e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 CDO74491.1 - 7.9e-06 25.2 0.5 4.3e-05 22.8 0.2 2.0 1 1 1 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 CDO74491.1 - 0.00056 20.3 0.1 0.0011 19.3 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 CDO74491.1 - 0.0084 16.8 0.2 0.015 16.0 0.2 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.15 CDO74491.1 - 0.011 14.9 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_3 PF03447.16 CDO74491.1 - 0.015 16.0 0.5 0.03 15.0 0.1 1.7 2 0 0 2 2 1 0 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CDO74491.1 - 0.019 15.1 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CDO74491.1 - 0.021 15.4 0.3 0.14 12.7 0.3 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 CDO74491.1 - 0.024 14.0 0.1 7.4 5.9 0.0 2.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 CDO74491.1 - 0.043 13.9 0.1 0.074 13.2 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 CDO74491.1 - 0.16 12.0 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 CDO74492.1 - 1.4e-09 38.1 0.2 2.3e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CDO74492.1 - 1e-05 25.2 0.1 7.7e-05 22.3 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 CDO74492.1 - 3.5e-05 22.9 0.0 0.0001 21.4 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 CDO74492.1 - 3.7e-05 23.8 0.0 6.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 CDO74492.1 - 0.00011 21.7 0.1 0.016 14.7 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CDO74492.1 - 0.00033 19.9 0.1 0.0013 17.9 0.0 1.9 1 1 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 CDO74492.1 - 0.00054 20.4 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CDO74492.1 - 0.0059 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 CDO74492.1 - 0.0072 16.9 0.1 0.021 15.4 0.1 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent FA_desaturase_2 PF03405.14 CDO74492.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase NAD_binding_10 PF13460.6 CDO74493.1 - 1.9e-10 40.9 0.2 3.2e-10 40.2 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CDO74493.1 - 9.5e-09 34.6 0.0 3.6e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 CDO74493.1 - 1.7e-08 34.3 0.2 2.6e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CDO74493.1 - 2.7e-08 33.6 0.0 7.1e-07 28.9 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CDO74493.1 - 6.6e-06 26.4 0.1 1e-05 25.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 CDO74493.1 - 5.8e-05 22.4 0.1 0.00011 21.5 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 CDO74493.1 - 0.0017 17.6 0.1 0.0026 16.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 CDO74493.1 - 0.0032 18.0 0.1 0.0083 16.7 0.1 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 CDO74493.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 CDO74493.1 - 0.071 13.2 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.20 CDO74493.1 - 0.091 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 CDO74493.1 - 0.094 13.4 0.1 0.17 12.6 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_10 PF13460.6 CDO74494.1 - 4.1e-10 39.9 0.2 7.3e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CDO74494.1 - 4.2e-09 35.8 0.0 1e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 CDO74494.1 - 1.5e-08 34.5 0.1 2.5e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CDO74494.1 - 7.5e-08 32.1 0.1 3.1e-07 30.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CDO74494.1 - 3.4e-05 24.1 0.1 5.4e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 CDO74494.1 - 0.00011 21.5 0.1 0.00026 20.2 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 CDO74494.1 - 0.002 18.6 0.1 0.0061 17.0 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 CDO74494.1 - 0.0029 16.8 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 CDO74494.1 - 0.0053 17.3 0.1 0.017 15.7 0.1 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 CDO74494.1 - 0.06 13.3 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 KR domain DapB_N PF01113.20 CDO74494.1 - 0.08 13.1 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 CDO74494.1 - 0.088 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 CDO74494.1 - 0.089 13.5 0.1 0.17 12.6 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Pex26 PF07163.12 CDO74495.1 - 0.028 13.7 0.0 0.07 12.4 0.0 1.6 1 0 0 1 1 1 0 Pex26 protein SRP-alpha_N PF04086.13 CDO74495.1 - 1.7 8.5 11.3 2.7 7.8 11.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GFO_IDH_MocA PF01408.22 CDO74496.1 - 1.6e-22 80.5 0.0 2.7e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.21 CDO74497.1 - 1e-19 71.0 0.0 5e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDO74497.1 - 8.4e-12 45.1 0.0 9.8e-05 21.9 0.0 3.1 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CDO74497.1 - 0.00056 19.1 0.0 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain DapB_N PF01113.20 CDO74497.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NPR3 PF03666.13 CDO74498.1 - 4.8e-91 305.9 0.1 4.8e-91 305.9 0.1 3.1 2 2 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 CDO74498.1 - 0.21 10.3 0.0 0.43 9.3 0.0 1.4 1 0 0 1 1 1 0 Nitrogen permease regulator 2 Glyco_trans_1_3 PF13528.6 CDO74499.1 - 8.4e-06 25.3 0.0 0.0037 16.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 ADH_N PF08240.12 CDO74501.1 - 6.4e-09 35.7 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO74501.1 - 7.8e-09 35.6 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO74501.1 - 5.7e-08 33.9 0.0 1e-07 33.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CDO74501.1 - 0.012 15.5 0.1 0.034 14.0 0.1 1.6 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 CDO74502.1 - 5.7e-16 58.7 0.1 1.7e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO74502.1 - 1.8e-07 31.0 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDO74502.1 - 7e-06 27.1 0.0 1.1e-05 26.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DSPc PF00782.20 CDO74503.1 - 2.2e-27 95.5 0.0 4.9e-21 74.9 0.0 3.3 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDO74503.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ADH_N PF08240.12 CDO74504.1 - 1.2e-08 34.7 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO74504.1 - 2.7e-06 27.4 0.0 5.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO74504.1 - 0.00083 20.4 0.0 0.0037 18.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO74505.1 - 8.2e-14 51.4 0.0 1.3e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO74505.1 - 1.4e-11 44.5 0.0 3.7e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO74505.1 - 0.00013 23.0 0.0 0.00026 22.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CDO74506.1 - 3e-12 46.6 0.0 5.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO74506.1 - 2.4e-07 31.9 0.0 3.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO74506.1 - 3.2e-07 30.2 0.0 6.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cupin_2 PF07883.11 CDO74506.1 - 0.086 12.6 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Cupin domain HATPase_c_4 PF13749.6 CDO74506.1 - 0.2 11.8 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal ADH_zinc_N PF00107.26 CDO74507.1 - 9.2e-30 103.3 0.0 4e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO74507.1 - 5.2e-13 50.2 0.0 2.9e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO74507.1 - 2e-12 47.0 0.0 4.8e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CDO74507.1 - 0.0002 20.9 0.0 0.15 11.6 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus MISS PF15822.5 CDO74507.1 - 0.0016 18.3 11.8 0.0041 17.0 1.3 2.6 3 0 0 3 3 3 2 MAPK-interacting and spindle-stabilising protein-like ADH_zinc_N PF00107.26 CDO74508.1 - 2.7e-16 59.8 0.0 5e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO74508.1 - 1.4e-07 31.3 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDO74508.1 - 0.036 15.1 0.0 0.095 13.8 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase GalKase_gal_bdg PF10509.9 CDO74509.1 - 1.7e-20 72.3 0.0 2.9e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CDO74509.1 - 9.2e-14 51.4 1.5 3.3e-13 49.6 1.3 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CDO74509.1 - 0.028 14.8 0.0 0.085 13.2 0.0 1.8 1 0 0 1 1 1 0 GHMP kinases C terminal DUF4628 PF15429.6 CDO74509.1 - 0.058 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) ADH_zinc_N PF00107.26 CDO74510.1 - 6.3e-15 55.3 0.2 4.1e-14 52.7 0.0 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO74510.1 - 2.9e-14 52.9 0.0 3.4e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CDO74510.1 - 1.3e-07 32.7 0.0 3.9e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CDO74510.1 - 2.3e-05 24.3 0.0 0.043 13.7 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of oxidoreductase DUF1953 PF09196.10 CDO74510.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) DUF4191 PF13829.6 CDO74511.1 - 0.058 12.7 3.0 1.5 8.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) HET PF06985.11 CDO74512.1 - 3.3e-18 66.5 2.6 1.5e-16 61.1 2.6 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 2OG-FeII_Oxy PF03171.20 CDO74512.1 - 1.2e-11 44.9 0.0 2.9e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CDO74512.1 - 4.9e-11 43.4 0.0 1.1e-10 42.2 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ABC_membrane PF00664.23 CDO74513.1 - 2.8e-35 122.3 9.0 3.8e-35 121.9 9.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDO74513.1 - 7e-33 114.0 0.0 6.6e-32 110.9 0.0 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CDO74513.1 - 0.00017 21.1 0.3 0.029 13.8 0.0 2.4 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 CDO74513.1 - 0.00093 19.6 0.0 0.01 16.3 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDO74513.1 - 0.0019 18.5 0.0 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CDO74513.1 - 0.0031 17.9 0.0 0.008 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CDO74513.1 - 0.012 15.4 0.4 0.71 9.6 0.0 2.7 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 CDO74513.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CDO74513.1 - 0.06 13.5 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CDO74513.1 - 0.077 12.8 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDO74513.1 - 0.086 12.7 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 CDO74513.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 CDO74513.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 CDO74514.1 - 0.02 15.4 3.5 0.02 15.4 3.5 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Atg14 PF10186.9 CDO74514.1 - 0.033 13.3 4.9 0.041 13.0 4.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 CDO74514.1 - 0.045 14.0 0.8 0.08 13.2 0.8 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Tho2 PF11262.8 CDO74514.1 - 0.13 11.5 0.5 0.17 11.1 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4364 PF14277.6 CDO74514.1 - 0.15 11.8 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) ADIP PF11559.8 CDO74514.1 - 0.18 11.9 11.1 0.092 12.8 8.7 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 CDO74514.1 - 0.29 10.5 6.5 0.54 9.6 6.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 CDO74514.1 - 3.8 7.6 6.1 1.6 8.8 3.9 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Helicase_C PF00271.31 CDO74518.1 - 2.3e-10 40.8 0.0 6.1e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Retrotran_gag_2 PF14223.6 CDO74518.1 - 1.8e-08 34.2 0.0 1.2e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_6 PF15288.6 CDO74518.1 - 0.00013 21.7 1.4 0.00081 19.2 1.4 2.4 1 0 0 1 1 1 1 Zinc knuckle DEAD PF00270.29 CDO74518.1 - 0.00046 20.0 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 CDO74518.1 - 0.039 14.0 5.6 0.14 12.2 0.5 2.9 2 0 0 2 2 2 0 Zinc knuckle Retrotran_gag_2 PF14223.6 CDO74519.1 - 1.2e-12 47.7 0.0 1.5e-11 44.1 0.0 2.2 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF659 PF04937.15 CDO74521.1 - 9e-18 64.6 0.0 1.8e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3450 PF11932.8 CDO74522.1 - 0.04 13.2 4.2 0.023 14.0 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Myb_DNA-bind_5 PF13873.6 CDO74522.1 - 0.11 12.6 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Tup_N PF08581.10 CDO74522.1 - 0.13 12.6 0.6 0.27 11.6 0.6 1.4 1 0 0 1 1 1 0 Tup N-terminal ZapB PF06005.12 CDO74522.1 - 0.15 12.5 2.0 0.29 11.6 2.0 1.3 1 0 0 1 1 1 0 Cell division protein ZapB ADIP PF11559.8 CDO74522.1 - 0.19 11.8 2.8 0.37 10.9 2.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 CDO74522.1 - 0.37 10.9 8.7 0.3 11.2 3.2 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DDE_Tnp_4 PF13359.6 CDO74523.1 - 7.8e-15 54.9 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plavaka PF18759.1 CDO74524.1 - 2.5e-120 401.6 0.0 3.6e-120 401.1 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase MANEC PF07502.14 CDO74524.1 - 0.072 13.4 0.6 0.16 12.3 0.6 1.5 1 0 0 1 1 1 0 MANEC domain TFIIA_gamma_C PF02751.14 CDO74525.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit gag-asp_proteas PF13975.6 CDO74526.1 - 0.002 18.7 0.0 0.0038 17.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO74526.1 - 0.0068 17.0 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CDO74526.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 CDO74528.1 - 4.5e-37 126.5 0.2 1.1e-36 125.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO74528.1 - 3.1e-31 108.6 0.0 5.1e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDO74528.1 - 9.1e-31 105.9 0.0 2.3e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDO74528.1 - 4.4e-17 61.9 0.2 8.9e-17 60.9 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO74528.1 - 1.6e-13 50.9 0.0 5.9e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 CDO74528.1 - 5.3e-12 45.9 0.2 3.4e-11 43.3 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO74528.1 - 1.7e-08 34.3 0.0 5.2e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Chromo PF00385.24 CDO74528.1 - 1.4e-06 28.1 0.1 3.1e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CDO74528.1 - 1.4e-06 28.4 0.1 3e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 CDO74530.1 - 5.6e-20 71.6 0.5 8.4e-20 71.0 0.5 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO74530.1 - 4.7e-06 26.5 0.0 7.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Carm_PH PF17888.1 CDO74530.1 - 0.087 13.2 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Carmil pleckstrin homology domain Transposase_21 PF02992.14 CDO74531.1 - 0.0053 16.0 0.0 0.0061 15.8 0.0 1.3 1 1 0 1 1 1 1 Transposase family tnp2 RVT_1 PF00078.27 CDO74534.1 - 1.6e-13 50.7 0.1 1.9e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pho88 PF10032.9 CDO74535.1 - 1.7e-78 262.1 1.2 1.9e-78 261.9 1.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pkinase_fungal PF17667.1 CDO74537.1 - 0.0026 16.6 0.0 0.0034 16.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase SNARE_assoc PF09335.11 CDO74538.1 - 8.2e-16 58.6 9.0 1.5e-15 57.7 7.4 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1772 PF08592.11 CDO74538.1 - 0.33 11.2 6.4 0.28 11.5 3.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) SNARE_assoc PF09335.11 CDO74539.1 - 1.5e-15 57.8 4.4 3.4e-15 56.6 4.4 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein BaxI_1 PF12811.7 CDO74539.1 - 0.066 12.8 0.3 0.066 12.8 0.3 2.3 2 1 0 3 3 3 0 Bax inhibitor 1 like SNARE_assoc PF09335.11 CDO74540.1 - 9e-14 52.0 6.4 9e-14 52.0 6.4 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein SNARE_assoc PF09335.11 CDO74541.1 - 4.5e-16 59.4 7.2 4.5e-16 59.4 7.2 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF1772 PF08592.11 CDO74541.1 - 0.11 12.8 1.5 2.6 8.3 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF5510 PF17629.2 CDO74541.1 - 2.4 8.2 7.2 7.3 6.6 0.3 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5510) LrgA PF03788.14 CDO74541.1 - 2.7 8.0 9.9 0.19 11.7 3.9 2.1 2 0 0 2 2 2 0 LrgA family PH PF00169.29 CDO74542.1 - 0.00022 21.7 0.0 0.00037 20.9 0.0 1.4 1 0 0 1 1 1 1 PH domain RVT_2 PF07727.14 CDO74544.1 - 1.5e-72 244.1 0.0 2e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.15 CDO74545.1 - 4.3e-10 39.6 0.0 6.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ARPC4 PF05856.12 CDO74545.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) DUF962 PF06127.11 CDO74546.1 - 6.3e-23 80.7 4.4 9.3e-23 80.1 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Bac_rhodopsin PF01036.18 CDO74546.1 - 0.051 13.1 2.8 0.072 12.7 2.8 1.3 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein adh_short_C2 PF13561.6 CDO74547.1 - 1.4e-60 204.8 0.2 1e-58 198.7 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO74547.1 - 1.8e-43 148.3 0.1 4.5e-32 111.1 0.3 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 CDO74547.1 - 8e-07 29.1 0.2 1.3e-06 28.5 0.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CDO74547.1 - 0.00028 20.8 1.1 0.00039 20.3 0.2 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CDO74547.1 - 0.17 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.22 CDO74548.1 - 2.1e-71 241.1 0.0 2.4e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 CDO74549.1 - 2.6e-29 101.7 3.2 2.6e-29 101.7 3.2 2.1 2 1 1 3 3 3 1 FAD binding domain MS_channel PF00924.18 CDO74550.1 - 1.3e-20 73.9 0.2 2.1e-20 73.2 0.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 CDO74550.1 - 4.4e-05 22.7 0.0 9.7e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDO74550.1 - 9.2e-05 22.1 0.1 0.00027 20.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CDO74550.1 - 0.0005 19.4 0.1 0.001 18.4 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CDO74550.1 - 0.057 13.9 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair HDV_ag PF01517.18 CDO74551.1 - 0.022 14.6 0.7 0.022 14.6 0.7 2.2 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen Herpes_IE2_3 PF03361.14 CDO74551.1 - 0.42 10.5 5.5 0.57 10.0 5.5 1.2 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 WDCP PF15390.6 CDO74551.1 - 1 7.7 12.7 1.2 7.5 12.7 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Golgin_A5 PF09787.9 CDO74551.1 - 1.3 8.4 20.4 1.7 8.0 20.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 GBP_C PF02841.14 CDO74551.1 - 1.4 8.2 21.7 1.8 7.9 21.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain GREB1 PF15782.5 CDO74551.1 - 1.4 5.9 11.8 1.6 5.7 11.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DSPc PF00782.20 CDO74551.1 - 1.7 8.4 6.1 0.94 9.3 3.7 1.7 1 1 1 2 2 2 0 Dual specificity phosphatase, catalytic domain Cluap1 PF10234.9 CDO74551.1 - 3.8 6.8 22.7 0.6 9.4 6.7 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 TMPIT PF07851.13 CDO74551.1 - 5 6.3 14.0 6.4 5.9 14.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein FAM76 PF16046.5 CDO74551.1 - 7.7 5.8 20.7 9.2 5.5 20.7 1.1 1 0 0 1 1 1 0 FAM76 protein Exonuc_VII_L PF02601.15 CDO74551.1 - 9.4 5.7 16.4 14 5.1 16.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Herpes_UL17 PF04559.12 CDO74552.1 - 0.33 9.7 6.5 0.39 9.5 6.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL17 protein DSPc PF00782.20 CDO74552.1 - 1.5 8.7 7.4 0.44 10.4 2.9 1.9 1 1 1 2 2 2 0 Dual specificity phosphatase, catalytic domain TMPIT PF07851.13 CDO74552.1 - 4.3 6.5 12.0 5.5 6.1 12.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4355 PF14265.6 CDO74552.1 - 8.9 6.6 26.6 9.2 6.5 12.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) F-box-like PF12937.7 CDO74555.1 - 6.8e-08 32.3 0.4 0.00032 20.5 0.2 2.6 2 0 0 2 2 2 2 F-box-like F-box_5 PF18511.1 CDO74555.1 - 0.012 15.2 0.1 14 5.3 0.1 3.3 3 0 0 3 3 3 0 F-box LRR_4 PF12799.7 CDO74555.1 - 0.085 13.3 0.6 39 4.8 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF2838 PF10998.8 CDO74556.1 - 2.6e-42 143.5 10.7 2.6e-42 143.5 10.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF5315 PF17242.2 CDO74556.1 - 0.027 14.3 0.2 0.094 12.5 0.0 1.9 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) DASH_Hsk3 PF08227.11 CDO74556.1 - 0.16 12.4 0.3 0.48 10.8 0.0 1.8 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like NifU_N PF01592.16 CDO74557.1 - 1e-54 184.1 0.2 1.8e-54 183.3 0.1 1.4 2 0 0 2 2 2 1 NifU-like N terminal domain Nop PF01798.18 CDO74558.1 - 8.9e-75 251.1 0.0 1.4e-74 250.5 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CDO74558.1 - 1.4e-33 116.4 2.0 4e-33 114.9 2.0 1.8 1 0 0 1 1 1 1 Prp31 C terminal domain TFIIF_alpha PF05793.12 CDO74558.1 - 0.86 8.1 9.5 1.3 7.5 9.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Helicase_C PF00271.31 CDO74559.1 - 3.7e-13 49.8 0.0 7.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC_6 PF15288.6 CDO74559.1 - 8.9e-06 25.5 1.0 2.3e-05 24.1 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle DEAD PF00270.29 CDO74559.1 - 0.00015 21.6 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AhpC-TSA_2 PF13911.6 CDO74559.1 - 0.0012 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AAA_14 PF13173.6 CDO74559.1 - 0.0038 17.3 0.0 0.052 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Peptidase_M20 PF01546.28 CDO74561.1 - 1.6e-27 96.6 0.0 2.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CDO74561.1 - 1.8e-08 34.3 0.0 5.4e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF659 PF04937.15 CDO74562.1 - 1.5e-10 41.1 0.0 3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CDO74562.1 - 0.043 13.6 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Pkinase PF00069.25 CDO74564.1 - 2.4e-08 33.7 0.0 3.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDO74564.1 - 2.2e-05 23.5 0.0 3.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CDO74564.1 - 6.2e-05 22.4 0.0 0.00013 21.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO74564.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 CDO74565.1 - 2.4e-23 82.6 44.4 2.4e-23 82.6 44.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO74565.1 - 2.8e-06 26.5 15.5 2.8e-06 26.5 15.5 3.4 2 1 2 4 4 4 1 Sugar (and other) transporter CRAL_TRIO PF00650.20 CDO74566.1 - 3.7e-26 91.8 0.0 6.2e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDO74566.1 - 1.6e-08 34.6 0.2 5.1e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain EcsC PF12787.7 CDO74566.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 EcsC protein family Hpt PF01627.23 CDO74567.1 - 8.1e-09 35.6 0.1 1.3e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Hpt domain SOG2 PF10428.9 CDO74567.1 - 2.5 7.2 10.4 2.8 7.1 10.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_M20 PF01546.28 CDO74568.1 - 1.5e-22 80.3 0.0 2.5e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 CDO74568.1 - 7.2e-20 71.0 9.3 0.00012 22.8 0.2 6.2 5 0 0 5 5 5 5 WD domain, G-beta repeat M20_dimer PF07687.14 CDO74568.1 - 1.5e-14 53.8 0.0 2.5e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain PQQ_3 PF13570.6 CDO74568.1 - 0.0012 19.3 0.1 2.5 8.7 0.0 3.8 3 0 0 3 3 3 2 PQQ-like domain Nup160 PF11715.8 CDO74568.1 - 0.0039 15.9 0.4 0.33 9.5 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 zf-RING_2 PF13639.6 CDO74569.1 - 1.6e-09 37.9 1.1 2.7e-09 37.2 1.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CDO74569.1 - 1.3e-08 34.4 0.9 2.4e-08 33.6 0.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDO74569.1 - 5.1e-06 26.2 1.1 9.2e-06 25.4 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDO74569.1 - 2.7e-05 24.4 1.0 5.8e-05 23.3 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CDO74569.1 - 3.1e-05 23.7 0.2 5.5e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO74569.1 - 0.00017 21.5 0.2 0.00036 20.5 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDO74569.1 - 0.00031 20.7 0.3 0.00054 19.9 0.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CDO74569.1 - 0.029 14.4 0.3 0.055 13.5 0.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CDO74569.1 - 0.096 12.6 0.4 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CDO74569.1 - 0.12 12.5 1.9 0.22 11.7 1.9 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CDO74569.1 - 0.21 11.2 1.6 0.34 10.6 1.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Methyltransf_32 PF13679.6 CDO74570.1 - 4.3e-23 82.0 0.0 1e-22 80.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO74570.1 - 0.0024 18.6 0.0 0.0079 16.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO74570.1 - 0.016 15.9 0.0 0.059 14.1 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain ATP12 PF07542.11 CDO74570.1 - 0.016 15.2 0.1 0.04 14.0 0.1 1.6 1 0 0 1 1 1 0 ATP12 chaperone protein Methyltransf_11 PF08241.12 CDO74570.1 - 0.029 15.0 0.0 0.065 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TRM13 PF05206.14 CDO74570.1 - 0.066 12.7 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase TRM13 HVSL PF09749.9 CDO74571.1 - 1e-39 136.5 0.0 2.8e-39 135.0 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 CDO74571.1 - 3.8e-06 26.9 0.3 9e-06 25.7 0.3 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily RRM_1 PF00076.22 CDO74572.1 - 8e-07 28.8 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDO74572.1 - 2.6e-06 27.4 0.0 4.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDO74572.1 - 3.1e-06 26.9 0.0 6.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CDO74572.1 - 5.7e-05 23.1 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Phage_TTP_13 PF16463.5 CDO74572.1 - 0.081 12.4 0.0 0.21 11.1 0.0 1.7 1 1 0 1 1 1 0 Phage tail tube protein family DUF659 PF04937.15 CDO74573.1 - 1.7e-13 50.7 0.0 2.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CDO74573.1 - 1.8e-05 24.4 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Mitoc_mL59 PF18126.1 CDO74575.1 - 6.3e-46 155.9 7.4 8e-46 155.5 7.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Sec62 PF03839.16 CDO74576.1 - 2.6e-52 177.5 5.8 8.5e-52 175.8 5.8 1.7 1 1 0 1 1 1 1 Translocation protein Sec62 TPR_12 PF13424.6 CDO74577.1 - 8.7e-06 25.9 11.9 0.031 14.6 0.1 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDO74577.1 - 8.5e-05 22.4 11.2 0.032 14.3 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO74577.1 - 0.00055 19.8 2.4 0.32 11.1 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 CDO74577.1 - 0.0035 17.4 2.7 0.49 10.5 0.6 3.4 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 CDO74577.1 - 0.0045 16.8 8.7 0.036 13.9 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDO74577.1 - 0.034 15.0 17.5 4.2 8.5 1.1 5.5 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDO74577.1 - 0.072 13.5 0.4 0.64 10.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDO74577.1 - 0.095 13.0 4.7 4.1 7.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDO74577.1 - 0.78 10.5 0.1 0.78 10.5 0.1 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDO74577.1 - 1.9 8.5 6.2 48 4.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 CDO74578.1 - 2.1e-43 148.1 0.1 3.3e-43 147.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO74578.1 - 2.1e-27 95.6 0.9 1.2e-26 93.3 0.3 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO74578.1 - 6.1e-06 26.4 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CDO74578.1 - 0.03 13.7 0.0 0.063 12.6 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Metallophos PF00149.28 CDO74579.1 - 1.9e-40 139.6 0.1 2.4e-40 139.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CDO74579.1 - 4.4e-17 62.3 1.4 7e-17 61.6 0.8 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain PH_9 PF15410.6 CDO74580.1 - 1.1e-10 41.9 0.2 2.4e-06 27.9 0.1 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 CDO74580.1 - 4.9e-07 30.2 0.0 0.00093 19.7 0.0 2.5 2 0 0 2 2 2 2 PH domain DUF1769 PF08588.10 CDO74582.1 - 9.1e-23 80.2 0.1 9.1e-23 80.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) DUF2076 PF09849.9 CDO74585.1 - 8.6e-06 26.0 9.8 1.2e-05 25.5 9.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 CDO74585.1 - 0.0025 17.9 1.7 0.0047 17.0 1.7 1.5 1 1 0 1 1 1 1 CHCH domain Arrestin_N PF00339.29 CDO74586.1 - 0.12 12.4 0.0 0.71 9.9 0.0 2.2 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain EXS PF03124.14 CDO74587.1 - 2.2e-67 227.8 23.4 2.6e-66 224.2 23.4 2.0 1 1 0 1 1 1 1 EXS family SPX PF03105.19 CDO74587.1 - 1.9e-38 133.4 0.7 3.5e-38 132.5 0.0 1.6 2 0 0 2 2 2 1 SPX domain Vps16_C PF04840.12 CDO74588.1 - 7.1e-85 284.9 0.3 9.6e-85 284.4 0.3 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 CDO74588.1 - 2e-80 270.6 0.0 2.9e-78 263.5 0.0 2.1 1 1 0 1 1 1 1 Vps16, N-terminal region RIB43A PF05914.12 CDO74588.1 - 0.023 13.4 0.5 0.036 12.8 0.5 1.2 1 0 0 1 1 1 0 RIB43A DnaJ PF00226.31 CDO74590.1 - 4.6e-14 52.3 0.0 7.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain APH PF01636.23 CDO74591.1 - 1.3e-14 54.7 0.0 3.9e-14 53.2 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Plavaka PF18759.1 CDO74593.1 - 1.6e-126 421.9 0.0 2.5e-126 421.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase MANEC PF07502.14 CDO74593.1 - 0.058 13.7 0.5 0.15 12.4 0.5 1.6 1 0 0 1 1 1 0 MANEC domain Rnk_N PF14760.6 CDO74594.1 - 0.069 13.6 0.5 0.55 10.8 0.2 2.4 2 0 0 2 2 2 0 Rnk N-terminus HTH_45 PF14947.6 CDO74595.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DUF1308 PF07000.11 CDO74596.1 - 0.0064 16.4 0.8 1.7 8.6 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1308) Tropomyosin_1 PF12718.7 CDO74596.1 - 0.13 12.4 0.1 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 Tropomyosin like Aldedh PF00171.22 CDO74597.1 - 3.1e-122 408.4 0.0 3.7e-122 408.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 CDO74597.1 - 0.068 13.2 0.6 0.13 12.3 0.6 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated tRNA-synt_2b PF00587.25 CDO74598.1 - 8.8e-37 126.8 0.0 1.9e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CDO74598.1 - 4.3e-19 68.7 7.7 4.3e-19 68.7 7.7 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 CDO74598.1 - 0.04 14.0 1.0 0.096 12.8 1.0 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF469 PF04320.14 CDO74598.1 - 0.063 14.1 0.5 0.26 12.2 0.5 2.1 1 1 0 1 1 1 0 Protein with unknown function (DUF469) eIF3_N PF09440.10 CDO74598.1 - 3.4 8.1 8.4 1.4 9.4 1.8 2.7 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain SET PF00856.28 CDO74599.1 - 7.7e-19 68.7 3.4 8.4e-19 68.6 0.1 2.8 3 1 0 3 3 3 1 SET domain RRM_1 PF00076.22 CDO74599.1 - 7.3e-08 32.1 0.0 5.7e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 CDO74599.1 - 1.8e-07 30.7 0.0 0.0003 20.4 0.0 2.5 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated N-SET PF11764.8 CDO74599.1 - 2e-07 31.3 9.1 2e-07 31.3 9.1 4.2 3 1 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N Acp26Ab PF05777.12 CDO74599.1 - 0.13 12.9 0.0 0.34 11.6 0.0 1.7 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) Abhydrolase_6 PF12697.7 CDO74601.1 - 3.8e-05 24.4 0.1 5.2e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CDO74601.1 - 0.0013 18.4 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 CDO74601.1 - 0.01 15.5 0.1 0.019 14.6 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 CDO74601.1 - 0.037 12.5 0.0 0.05 12.1 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II WD40 PF00400.32 CDO74604.1 - 1.6e-10 41.4 2.3 0.04 14.8 0.0 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO74604.1 - 1.8e-05 25.0 0.0 0.23 11.8 0.0 3.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDO74604.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain CDC45 PF02724.14 CDO74604.1 - 2.3 6.4 13.4 3.3 5.9 13.4 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 CDO74604.1 - 3.5 6.9 18.1 5.4 6.2 18.1 1.2 1 0 0 1 1 1 0 BUD22 Fes1 PF08609.10 CDO74605.1 - 0.00047 21.0 2.0 0.00069 20.4 0.6 2.1 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 Dynactin_p22 PF07426.11 CDO74605.1 - 0.0028 17.6 0.5 0.16 11.8 0.1 2.2 2 0 0 2 2 2 1 Dynactin subunit p22 DUF1043 PF06295.12 CDO74605.1 - 0.057 13.4 0.1 0.057 13.4 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) DUF4400 PF14348.6 CDO74605.1 - 0.066 12.7 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Baculo_PEP_C PF04513.12 CDO74605.1 - 0.15 12.1 1.3 24 5.0 0.0 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Het-C PF07217.11 CDO74605.1 - 0.19 10.2 2.5 0.85 8.1 2.5 1.8 1 1 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF3088 PF11287.8 CDO74606.1 - 0.12 12.2 0.0 0.66 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3088) Alpha-amylase PF00128.24 CDO74608.1 - 1e-20 74.6 0.3 1.5e-19 70.7 0.1 2.6 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 CDO74608.1 - 2.5e-14 53.6 0.0 4.4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 CDO74608.1 - 2.1e-07 30.6 0.0 4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.25 CDO74609.1 - 2.3e-70 237.0 0.0 3.1e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO74609.1 - 6.5e-48 163.3 0.0 1.1e-47 162.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 CDO74609.1 - 6.3e-14 52.2 0.1 1.4e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDO74609.1 - 7.9e-13 48.3 0.1 1.7e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 CDO74609.1 - 1.9e-12 47.4 0.0 3.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 CDO74609.1 - 1.1e-06 28.2 0.0 0.00052 19.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like SAM_4 PF18017.1 CDO74609.1 - 0.0075 16.2 0.0 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) APH PF01636.23 CDO74609.1 - 0.019 14.9 0.1 0.11 12.4 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family RNA_pol_3_Rpc31 PF11705.8 CDO74609.1 - 0.14 12.3 8.4 0.38 11.0 8.4 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4746 PF15928.5 CDO74609.1 - 0.31 10.4 8.4 0.52 9.7 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PPP4R2 PF09184.11 CDO74609.1 - 1.9 8.0 13.2 3.5 7.1 13.2 1.5 1 0 0 1 1 1 0 PPP4R2 TRM PF02005.16 CDO74610.1 - 1.2e-92 311.0 0.3 8.7e-62 209.5 0.2 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DUF4796 PF16044.5 CDO74610.1 - 0.052 13.1 0.1 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) PrmA PF06325.13 CDO74610.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 CDO74610.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 2 0 0 2 2 2 0 Met-10+ like-protein Ferric_reduct PF01794.19 CDO74611.1 - 3e-16 59.7 12.8 3e-16 59.7 12.8 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CDO74611.1 - 1.7e-11 44.1 0.0 4.6e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CDO74611.1 - 0.00018 21.6 0.1 0.00029 21.0 0.1 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain O-antigen_lig PF13425.6 CDO74611.1 - 0.045 12.6 0.1 0.045 12.6 0.1 1.6 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Presenilin PF01080.17 CDO74611.1 - 0.42 9.3 2.3 0.82 8.4 2.3 1.4 1 0 0 1 1 1 0 Presenilin PsbT PF01405.17 CDO74611.1 - 4.1 7.3 5.4 17 5.3 5.4 2.1 1 0 0 1 1 1 0 Photosystem II reaction centre T protein DDE_Tnp_4 PF13359.6 CDO74612.1 - 8.7e-18 64.5 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO74612.1 - 2.6e-05 23.9 0.0 6.4e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO74612.1 - 0.0042 16.7 0.1 0.0072 16.0 0.1 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO74612.1 - 0.031 14.6 0.1 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 CDO74613.1 - 0.00013 22.8 0.1 0.00035 21.5 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO74613.1 - 0.001 19.4 0.4 0.0027 18.0 0.2 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain XPG_I PF00867.18 CDO74615.1 - 6.4e-18 64.9 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDO74615.1 - 3.4e-05 24.2 0.0 7.7e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CDO74615.1 - 0.22 11.0 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing Spherulin4 PF12138.8 CDO74616.1 - 8.6e-49 166.3 0.0 9.8e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 UPRTase PF14681.6 CDO74617.1 - 4.2e-68 228.9 0.0 4.7e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CDO74617.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain FAD_binding_1 PF00667.20 CDO74618.1 - 6.7e-37 127.2 0.0 2.3e-18 66.6 0.0 2.3 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.21 CDO74618.1 - 1.4e-07 32.1 0.0 3.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Glyco_hydro_9 PF00759.19 CDO74619.1 - 2.8e-107 359.7 13.6 3.4e-107 359.4 13.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 SKG6 PF08693.10 CDO74619.1 - 0.0013 18.1 6.6 0.0025 17.2 6.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Saf_2TM PF18303.1 CDO74619.1 - 0.13 11.9 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain GFO_IDH_MocA PF01408.22 CDO74620.1 - 6e-21 75.5 0.1 1.8e-20 74.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CDO74620.1 - 5.6e-06 26.4 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 CDO74620.1 - 0.00061 20.4 0.0 0.0014 19.3 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 CDO74620.1 - 0.029 14.5 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 CDO74620.1 - 0.062 13.7 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F-box-like PF12937.7 CDO74621.1 - 1.4e-09 37.7 0.2 3.4e-09 36.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like Methyltransf_8 PF05148.15 CDO74622.1 - 1.4e-64 217.9 0.0 1.7e-63 214.4 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CDO74622.1 - 2.5e-05 24.9 0.0 8.2e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO74622.1 - 0.0019 18.9 0.2 0.015 16.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO74622.1 - 0.014 15.2 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDO74622.1 - 0.19 12.5 0.5 0.71 10.6 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain DUF87 PF01935.17 CDO74623.1 - 0.00031 20.9 0.0 0.017 15.3 0.0 2.4 2 1 0 2 2 2 1 Helicase HerA, central domain Zot PF05707.12 CDO74623.1 - 0.0027 17.4 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 CDO74623.1 - 0.0059 16.9 0.1 0.3 11.4 0.1 2.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 CDO74623.1 - 0.047 13.5 0.0 0.78 9.5 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 CDO74623.1 - 0.16 12.4 0.4 0.68 10.3 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.9 CDO74623.1 - 0.24 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) JmjC PF02373.22 CDO74624.1 - 1.1e-14 54.8 0.0 2.9e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase C1_1 PF00130.22 CDO74624.1 - 0.014 15.2 2.6 0.034 14.0 2.6 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 CDO74624.1 - 0.025 14.7 1.9 0.065 13.4 1.9 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger FYVE PF01363.21 CDO74624.1 - 0.56 10.4 11.9 0.038 14.1 6.0 2.1 2 0 0 2 2 2 0 FYVE zinc finger Prok-RING_2 PF14445.6 CDO74624.1 - 1.3 9.3 12.5 0.21 11.8 3.7 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Response_reg PF00072.24 CDO74625.1 - 1.4e-22 80.0 0.0 1.4e-16 60.7 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain Oxidored_nitro PF00148.19 CDO74625.1 - 0.015 14.0 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DUF3546 PF12066.8 CDO74626.1 - 9.1e-15 54.8 2.0 2.5e-14 53.4 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 CDO74626.1 - 1.2e-14 55.1 1.4 4.7e-14 53.2 0.1 2.5 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 CDO74626.1 - 0.00028 20.6 0.7 0.00092 19.0 0.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.7 CDO74626.1 - 0.054 13.8 2.2 0.79 10.1 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.22 CDO74627.1 - 0.0004 20.1 0.0 0.046 13.5 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AIM3 PF17096.5 CDO74627.1 - 1.4 9.9 10.9 0.33 11.9 0.8 2.7 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Golgin_A5 PF09787.9 CDO74628.1 - 0.14 11.6 17.2 0.16 11.4 17.2 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 GNAT_acetyltran PF12746.7 CDO74628.1 - 0.19 11.3 4.3 0.22 11.1 4.3 1.0 1 0 0 1 1 1 0 GNAT acetyltransferase Cas_DxTHG PF09455.10 CDO74628.1 - 0.28 10.7 6.3 0.33 10.5 6.3 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Mu-like_Pro PF10123.9 CDO74628.1 - 0.47 10.0 12.8 0.55 9.7 12.8 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein RuvC PF02075.17 CDO74628.1 - 0.6 10.0 6.6 1.3 8.9 5.7 1.9 1 1 1 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC VTC PF09359.10 CDO74628.1 - 0.7 9.2 11.5 2 7.7 11.5 1.7 1 1 0 1 1 1 0 VTC domain AAA_13 PF13166.6 CDO74628.1 - 0.97 8.0 15.7 1.2 7.7 15.7 1.1 1 0 0 1 1 1 0 AAA domain CENP-Q PF13094.6 CDO74628.1 - 1.1 9.5 22.0 3.2 7.9 22.0 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.19 CDO74628.1 - 1.2 6.9 12.3 1.4 6.7 12.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 CDO74628.1 - 1.5 8.0 13.0 2.3 7.4 13.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 CDO74628.1 - 1.7 8.1 11.7 2.1 7.9 11.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-K PF11802.8 CDO74628.1 - 3.1 7.3 22.1 4.1 6.9 22.1 1.1 1 0 0 1 1 1 0 Centromere-associated protein K LMBR1 PF04791.16 CDO74628.1 - 3.3 6.5 9.3 3.7 6.3 9.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein BLYB PF05289.11 CDO74628.1 - 3.4 7.9 12.4 25 5.1 12.4 1.9 1 1 0 1 1 1 0 Borrelia hemolysin accessory protein P16-Arc PF04699.14 CDO74628.1 - 4.2 7.9 15.5 2.5 8.6 12.2 1.8 1 1 1 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Presenilin PF01080.17 CDO74628.1 - 5 5.8 7.4 5.3 5.7 7.4 1.0 1 0 0 1 1 1 0 Presenilin Fib_alpha PF08702.10 CDO74628.1 - 5.3 7.2 13.1 12 6.1 5.9 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family dUTPase PF00692.19 CDO74630.1 - 2e-37 127.8 0.0 2.9e-34 117.5 0.0 2.1 1 1 1 2 2 2 2 dUTPase Peptidase_M43 PF05572.13 CDO74631.1 - 7.1e-15 55.2 0.1 1.4e-14 54.3 0.0 1.5 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CDO74631.1 - 1.7e-06 28.3 0.1 2.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CDO74631.1 - 0.0021 18.6 0.0 0.0038 17.7 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 CDO74631.1 - 0.024 14.3 2.2 0.029 14.0 0.5 1.9 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 CDO74631.1 - 0.039 12.9 0.1 0.051 12.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_2 PF13574.6 CDO74631.1 - 0.059 13.3 0.1 0.075 12.9 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CDO74631.1 - 0.093 12.4 2.2 0.12 12.0 1.0 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 CDO74632.1 - 1.6e-13 50.8 0.6 4.7e-13 49.3 0.1 1.9 1 1 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CDO74632.1 - 1.6e-06 28.4 0.0 2.5e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CDO74632.1 - 1.8e-05 25.2 0.0 3.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CDO74632.1 - 0.0082 15.8 0.2 0.02 14.5 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 CDO74632.1 - 0.28 10.8 2.4 0.39 10.3 1.6 1.5 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase MerR PF00376.23 CDO74633.1 - 2.5 7.9 4.5 1.4 8.7 0.1 2.4 3 0 0 3 3 3 0 MerR family regulatory protein ACBP PF00887.19 CDO74634.1 - 0.00024 21.2 0.4 0.61 10.3 0.0 2.4 1 1 1 2 2 2 2 Acyl CoA binding protein Imm41 PF15592.6 CDO74634.1 - 0.22 11.9 0.0 0.37 11.1 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 41 ADH_zinc_N PF00107.26 CDO74635.1 - 9.6e-18 64.4 0.1 1.8e-17 63.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO74635.1 - 2.9e-10 40.0 1.6 7.5e-10 38.7 1.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ThiF PF00899.21 CDO74635.1 - 0.0024 17.3 1.5 0.008 15.6 1.0 2.0 2 0 0 2 2 2 1 ThiF family AlaDh_PNT_C PF01262.21 CDO74635.1 - 0.0054 16.0 0.1 0.0098 15.2 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CDO74635.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CLLAC PF15675.5 CDO74635.1 - 0.44 10.2 2.5 0.97 9.0 2.5 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain Vfa1 PF08432.10 CDO74636.1 - 3.2e-40 138.4 0.1 3.6e-40 138.2 0.1 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 GNAT_acetyltr_2 PF13718.6 CDO74636.1 - 0.024 14.0 0.4 0.029 13.8 0.4 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 XRCC4 PF06632.12 CDO74636.1 - 0.027 13.3 7.4 0.035 13.0 7.4 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF908 PF06012.12 CDO74636.1 - 0.029 13.8 0.8 0.038 13.4 0.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RFXA_RFXANK_bdg PF15289.6 CDO74636.1 - 0.041 14.2 4.2 0.059 13.7 4.2 1.2 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain CPSF100_C PF13299.6 CDO74636.1 - 0.042 14.0 4.4 0.054 13.7 4.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ATP-synt_E PF05680.12 CDO74636.1 - 0.076 13.4 6.1 0.16 12.3 6.1 1.5 1 0 0 1 1 1 0 ATP synthase E chain RR_TM4-6 PF06459.12 CDO74636.1 - 0.11 12.3 3.3 0.13 12.1 3.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.16 CDO74636.1 - 0.15 11.4 8.1 0.18 11.2 8.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Rtf2 PF04641.12 CDO74636.1 - 0.28 10.5 11.6 0.072 12.4 8.5 1.5 2 0 0 2 2 2 0 Rtf2 RING-finger FAM176 PF14851.6 CDO74636.1 - 0.37 10.5 4.5 0.48 10.1 4.5 1.2 1 0 0 1 1 1 0 FAM176 family ANAPC_CDC26 PF10471.9 CDO74636.1 - 0.47 11.3 8.0 0.11 13.3 3.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Pex14_N PF04695.13 CDO74636.1 - 0.6 10.8 6.3 0.84 10.3 6.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.14 CDO74636.1 - 1.8 6.8 6.9 2.1 6.6 6.9 1.0 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.8 CDO74636.1 - 2.3 7.0 9.6 3 6.7 9.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Connexin PF00029.19 CDO74636.1 - 4.2 7.1 4.8 5.7 6.6 4.8 1.2 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 CDO74636.1 - 5.2 5.7 4.9 6.3 5.4 4.9 1.1 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 CDO74636.1 - 8.2 6.2 10.3 13 5.5 10.3 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Nucleoside_tran PF01733.18 CDO74637.1 - 5e-46 157.5 10.4 5e-46 157.5 10.4 1.6 2 0 0 2 2 2 1 Nucleoside transporter Retrotrans_gag PF03732.17 CDO74638.1 - 1.6e-07 31.5 1.1 8.8e-07 29.1 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 CDO74638.1 - 2.2e-05 24.3 2.2 4.5e-05 23.3 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDO74638.1 - 0.0003 20.5 1.7 0.00054 19.7 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle RT_RNaseH PF17917.1 CDO74639.1 - 5.1e-24 84.6 0.0 1.1e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO74639.1 - 1.1e-15 57.5 0.0 2.5e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO74639.1 - 3.3e-15 56.2 0.0 5.4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CDO74639.1 - 7.6e-08 32.2 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CDO74639.1 - 1.2e-05 25.7 0.0 2.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO74639.1 - 0.00013 22.5 0.0 0.00033 21.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CDO74639.1 - 0.041 13.7 0.0 0.6 9.9 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease rve PF00665.26 CDO74640.1 - 1.7e-07 31.4 0.0 2.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Pkinase_Tyr PF07714.17 CDO74643.1 - 2.6e-46 158.0 0.0 4.4e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDO74643.1 - 1e-35 123.4 0.0 2.7e-35 122.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDO74643.1 - 1.3e-05 24.7 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO74643.1 - 0.00029 20.8 0.0 0.00073 19.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDO74643.1 - 0.00036 20.2 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 CDO74643.1 - 0.0068 15.8 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DPBB_1 PF03330.18 CDO74644.1 - 3.2e-09 36.9 0.2 6.6e-09 35.9 0.2 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 CDO74644.1 - 0.013 15.4 0.6 0.021 14.7 0.6 1.4 1 1 0 1 1 1 0 Barwin family DUF4473 PF14747.6 CDO74644.1 - 0.11 13.0 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Gti1_Pac2 PF09729.9 CDO74645.1 - 4.7e-31 108.3 0.1 2.2e-27 96.3 0.2 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family DNA_mis_repair PF01119.19 CDO74646.1 - 2.3e-18 66.0 0.0 5.8e-18 64.7 0.0 1.7 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CDO74646.1 - 3.2e-12 46.5 0.1 7.8e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 CDO74646.1 - 1.8e-11 44.0 2.0 1.4e-09 37.9 2.0 2.9 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 CDO74646.1 - 1.1e-08 35.5 0.1 2.5e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Coilin_N PF15862.5 CDO74648.1 - 0.96 9.3 7.9 1 9.1 7.4 1.3 1 1 0 1 1 1 0 Coilin N-terminus DBINO PF13892.6 CDO74648.1 - 1.2 9.5 16.1 2.1 8.7 16.1 1.4 1 0 0 1 1 1 0 DNA-binding domain Asp-B-Hydro_N PF05279.11 CDO74648.1 - 6.8 6.7 13.5 8.7 6.3 13.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Methyltransf_1N PF02870.15 CDO74649.1 - 0.019 15.7 0.1 0.028 15.2 0.1 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain TSNAXIP1_N PF15739.5 CDO74649.1 - 0.06 13.7 0.7 0.085 13.2 0.7 1.2 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus CENP-Q PF13094.6 CDO74649.1 - 0.14 12.4 6.1 0.2 11.9 6.1 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Zn_clus PF00172.18 CDO74649.1 - 2.7 8.2 7.3 6.5 7.0 7.3 1.6 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Integrase_H2C2 PF17921.1 CDO74650.1 - 3.4e-18 65.5 0.1 9.8e-18 64.0 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO74650.1 - 3.5e-15 56.2 0.0 6.6e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO74650.1 - 3.7e-07 29.9 0.1 7.3e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CDO74650.1 - 5.2e-07 29.8 0.1 1e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Retrotran_gag_2 PF14223.6 CDO74651.1 - 4.2e-13 49.2 0.1 5.8e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 CDO74651.1 - 0.24 11.2 1.4 0.62 9.8 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF4219 PF13961.6 CDO74651.1 - 0.26 11.0 1.1 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) zf-CCHC_5 PF14787.6 CDO74651.1 - 0.3 10.8 1.6 0.71 9.6 1.6 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger rve PF00665.26 CDO74652.1 - 2.9e-18 66.2 0.0 5.3e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO74652.1 - 3.7e-12 46.1 0.1 5.7e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO74652.1 - 2.9e-09 36.6 0.3 6.2e-09 35.6 0.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO74652.1 - 0.017 14.9 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF4820 PF16091.5 CDO74652.1 - 0.37 10.1 2.1 0.64 9.4 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MRI PF15325.6 CDO74653.1 - 0.12 13.5 0.6 0.22 12.6 0.6 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection 2-oxoacid_dh PF00198.23 CDO74654.1 - 2.3e-72 243.2 1.2 1.5e-71 240.5 0.0 2.0 1 1 1 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDO74654.1 - 2.2e-19 69.1 0.2 4.6e-19 68.0 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDO74654.1 - 6.9e-06 25.8 0.0 0.00064 19.5 0.0 2.7 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 CDO74654.1 - 2.8e-05 24.8 0.1 0.087 13.5 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 CDO74654.1 - 0.0031 17.4 0.2 0.0071 16.2 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein DUF4674 PF15719.5 CDO74654.1 - 8.6 6.4 7.7 1 9.3 2.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4674) Transposase_21 PF02992.14 CDO74655.1 - 8.9e-11 41.4 0.0 2.3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 KDZ PF18758.1 CDO74657.1 - 3.3e-74 249.2 0.0 5.5e-74 248.5 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 CDO74657.1 - 0.004 17.3 0.1 0.0097 16.1 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 CDO74657.1 - 0.065 13.1 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases SlyX PF04102.12 CDO74658.1 - 0.0066 17.0 3.0 0.025 15.2 3.0 1.9 1 0 0 1 1 1 1 SlyX HMG_box PF00505.19 CDO74658.1 - 0.0068 16.8 0.2 0.0068 16.8 0.2 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMMR_N PF15905.5 CDO74658.1 - 0.011 15.2 2.2 0.011 15.2 2.2 1.7 2 0 0 2 2 1 0 Hyaluronan mediated motility receptor N-terminal CC2-LZ PF16516.5 CDO74658.1 - 0.013 15.9 3.6 0.013 15.9 3.6 2.1 2 0 0 2 2 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TPD52 PF04201.15 CDO74658.1 - 0.038 13.6 2.6 0.046 13.3 0.9 1.9 2 0 0 2 2 2 0 Tumour protein D52 family FlaC_arch PF05377.11 CDO74658.1 - 0.05 14.0 2.2 0.14 12.6 2.2 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) GAS PF13851.6 CDO74658.1 - 0.1 11.9 5.3 0.31 10.4 5.3 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding SKA2 PF16740.5 CDO74658.1 - 0.12 12.2 3.3 0.37 10.6 3.3 1.8 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Tnp_22_trimer PF17489.2 CDO74658.1 - 0.12 12.4 1.9 0.28 11.2 1.9 1.6 1 0 0 1 1 1 0 L1 transposable element trimerization domain AAA_13 PF13166.6 CDO74658.1 - 0.18 10.4 2.4 0.4 9.3 2.4 1.5 1 0 0 1 1 1 0 AAA domain COG2 PF06148.11 CDO74658.1 - 0.24 11.5 2.1 0.63 10.1 1.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GPO PF05929.11 CDO74658.1 - 0.24 11.0 2.2 0.58 9.7 2.2 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PKcGMP_CC PF16808.5 CDO74658.1 - 0.25 11.2 9.9 0.45 10.4 6.5 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF16 PF01519.16 CDO74658.1 - 0.33 11.4 3.1 0.62 10.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4404 PF14357.6 CDO74658.1 - 0.4 11.3 4.0 1.7 9.4 4.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Fib_alpha PF08702.10 CDO74658.1 - 0.41 10.8 7.1 0.038 14.2 1.6 2.0 3 0 0 3 3 1 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 CDO74658.1 - 0.7 10.4 9.1 0.21 12.1 4.0 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 CDO74658.1 - 1.6 8.0 7.7 0.16 11.3 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SKA1 PF07160.12 CDO74658.1 - 1.7 8.4 7.2 0.066 13.0 0.7 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 GAT PF03127.14 CDO74658.1 - 2 8.8 7.4 0.49 10.7 2.7 2.2 2 0 0 2 2 2 0 GAT domain Csm1_N PF18504.1 CDO74658.1 - 2.1 8.7 10.2 2.5 8.5 7.5 2.7 2 1 0 2 2 1 0 Csm1 N-terminal domain AAA_23 PF13476.6 CDO74658.1 - 2.4 8.6 5.3 0.81 10.2 2.3 1.7 2 0 0 2 2 1 0 AAA domain Tropomyosin_1 PF12718.7 CDO74658.1 - 3.6 7.7 12.6 0.093 12.9 5.2 2.1 2 0 0 2 2 2 0 Tropomyosin like UPF0184 PF03670.13 CDO74658.1 - 5.5 7.5 8.6 3 8.3 5.8 2.1 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0184) Spc7 PF08317.11 CDO74658.1 - 7.3 5.4 12.4 0.11 11.4 4.2 2.0 3 0 0 3 3 3 0 Spc7 kinetochore protein Astro_capsid_p PF12226.8 CDO74659.1 - 0.21 10.7 2.5 0.3 10.2 2.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Plavaka PF18759.1 CDO74660.1 - 1e-26 94.0 0.0 2.4e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Plavaka transposase HMG_box_2 PF09011.10 CDO74662.1 - 0.3 11.7 2.2 0.52 10.9 0.1 2.4 2 0 0 2 2 2 0 HMG-box domain V-ATPase_G PF03179.15 CDO74662.1 - 0.46 11.0 3.0 0.28 11.7 0.3 2.0 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Methyltransf_16 PF10294.9 CDO74663.1 - 6.9e-10 38.9 0.0 3e-06 27.1 0.0 2.3 1 1 1 2 2 2 2 Lysine methyltransferase Peptidase_S15 PF02129.18 CDO74664.1 - 2.1e-08 34.1 0.1 9.5e-08 31.9 0.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 CDO74664.1 - 0.00042 20.0 0.1 0.24 11.0 0.0 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO74664.1 - 0.0097 15.2 0.0 0.037 13.3 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDO74665.1 - 9.3e-17 61.5 0.2 1.6e-11 44.4 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO74665.1 - 1.1e-10 41.2 0.0 6.7e-10 38.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO74665.1 - 8.7e-10 39.6 0.9 1.8e-09 38.5 0.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CDO74665.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain XRN_M PF17846.1 CDO74666.1 - 3.2e-99 332.9 8.4 7.2e-99 331.7 8.4 1.5 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CDO74666.1 - 2.9e-93 311.8 0.0 5.3e-93 310.9 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 CDO74666.1 - 4.6e-77 258.1 0.0 1.1e-76 256.9 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 CDO74666.1 - 2.7e-30 104.4 0.1 8.1e-30 102.9 0.1 1.9 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 CDO74666.1 - 7e-23 80.5 0.1 2.2e-22 78.9 0.1 1.9 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 CDO74666.1 - 2.3e-05 24.4 0.1 5.5e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 Sterile PF03015.19 CDO74666.1 - 0.0041 17.3 0.1 0.033 14.4 0.0 2.5 2 0 0 2 2 2 1 Male sterility protein Plavaka PF18759.1 CDO74667.1 - 2.7e-116 388.3 0.0 4.3e-116 387.7 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DNA_pol_phi PF04931.13 CDO74667.1 - 1.6 6.7 7.1 2.3 6.2 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Acetyltransf_7 PF13508.7 CDO74669.1 - 1.2e-08 35.3 0.0 2.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDO74669.1 - 3e-08 33.6 0.0 4.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CDO74669.1 - 1e-06 28.8 0.1 0.00017 21.6 0.1 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO74669.1 - 2.3e-06 27.8 0.0 2.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CDO74669.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein GMP_synt_C PF00958.22 CDO74670.1 - 1e-45 153.7 0.1 1.9e-45 152.8 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CDO74670.1 - 1.1e-34 119.8 0.0 2.2e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CDO74670.1 - 2.3e-11 43.3 0.2 5e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CDO74670.1 - 7e-09 35.7 0.0 1.6e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 CDO74670.1 - 0.00057 18.8 0.1 0.001 18.0 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 CDO74670.1 - 0.0021 17.7 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 CDO74670.1 - 0.0092 15.5 0.0 0.047 13.2 0.0 2.1 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 CDO74670.1 - 0.022 14.1 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 CDO74670.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family GST_N_3 PF13417.6 CDO74671.1 - 2.5e-13 50.2 0.0 4.5e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO74671.1 - 8.8e-12 45.2 0.0 1.7e-11 44.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO74671.1 - 1.8e-11 44.2 0.0 3.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO74671.1 - 0.0011 18.9 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO74671.1 - 0.041 14.1 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CBM_48 PF02922.18 CDO74671.1 - 0.08 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glutaredoxin PF00462.24 CDO74671.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin PrpF PF04303.13 CDO74672.1 - 1.4e-67 228.3 0.5 1.6e-67 228.1 0.5 1.0 1 0 0 1 1 1 1 PrpF protein Abhydrolase_1 PF00561.20 CDO74673.1 - 1.6e-18 67.3 0.2 7.8e-18 65.0 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO74673.1 - 1.2e-11 44.4 0.0 1.4e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO74673.1 - 2.3e-10 41.4 0.0 3e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CDO74673.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.22 CDO74673.1 - 0.025 14.0 0.4 1 8.7 0.0 2.7 3 0 0 3 3 3 0 Serine carboxypeptidase Thioesterase PF00975.20 CDO74673.1 - 0.031 14.4 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 CDO74673.1 - 0.037 13.8 0.0 0.087 12.5 0.0 1.6 1 1 1 2 2 2 0 PGAP1-like protein Abhydrolase_1 PF00561.20 CDO74674.1 - 2.4e-18 66.7 0.3 3.9e-17 62.7 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO74674.1 - 2.9e-11 44.4 0.6 3.9e-11 44.0 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO74674.1 - 1.5e-08 34.2 0.0 2.4e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CDO74674.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 CDO74674.1 - 0.092 12.8 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 CDO74674.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 CDO74674.1 - 0.2 11.5 0.0 0.54 10.0 0.0 1.7 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Whi5 PF08528.11 CDO74676.1 - 7.7e-06 25.4 0.8 1.2e-05 24.8 0.8 1.3 1 0 0 1 1 1 1 Whi5 like RVT_2 PF07727.14 CDO74678.1 - 1.3e-43 149.4 0.0 1.1e-42 146.4 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO74678.1 - 4.9e-12 46.1 0.1 1.2e-11 44.8 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO74678.1 - 8.5e-05 22.2 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO74678.1 - 0.00033 20.5 0.0 0.00082 19.2 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO74678.1 - 0.00051 19.8 0.1 0.0022 17.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 CDO74678.1 - 0.047 13.8 0.6 0.098 12.8 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.19 CDO74679.1 - 2.8e-23 82.5 0.0 4.7e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CDO74679.1 - 2e-09 37.3 0.3 5.3e-09 36.0 0.3 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 CDO74679.1 - 0.0013 18.4 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_ISL3 PF13542.6 CDO74679.1 - 0.11 11.9 0.0 0.35 10.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF2089 PF09862.9 CDO74679.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Cation_efflux PF01545.21 CDO74680.1 - 5.1e-43 147.1 24.2 5.1e-43 147.1 24.2 3.8 2 2 1 3 3 3 1 Cation efflux family Chordopox_A13L PF05961.11 CDO74680.1 - 0.28 11.4 0.9 2.6 8.3 0.0 2.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Rcd1 PF04078.13 CDO74681.1 - 2.7e-97 325.1 5.6 1.6e-88 296.4 1.4 2.0 1 1 1 2 2 2 2 Cell differentiation family, Rcd1-like SDH_alpha PF03313.15 CDO74682.1 - 6.1e-55 186.7 0.0 2.9e-41 141.9 0.0 2.1 1 1 1 2 2 2 2 Serine dehydratase alpha chain SDH_beta PF03315.15 CDO74682.1 - 1.1e-38 133.1 0.0 4.5e-38 131.0 0.0 2.0 1 1 0 1 1 1 1 Serine dehydratase beta chain SET PF00856.28 CDO74683.1 - 1.6e-09 38.3 0.0 2.7e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 SET domain RhoGAP PF00620.27 CDO74684.1 - 1.2e-41 142.0 0.0 2e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 CDO74684.1 - 2.1e-17 63.5 0.0 4.7e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CDO74684.1 - 0.0026 18.0 0.0 0.0079 16.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PX PF00787.24 CDO74684.1 - 0.12 12.3 0.0 0.45 10.5 0.0 2.0 1 1 0 1 1 1 0 PX domain Cep57_CLD_2 PF14197.6 CDO74684.1 - 0.24 11.5 3.6 0.69 10.0 3.6 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 SHR3_chaperone PF08229.11 CDO74685.1 - 2.4e-37 127.7 0.1 4.3e-35 120.4 0.0 2.8 2 1 0 2 2 2 2 ER membrane protein SH3 DDE_3 PF13358.6 CDO74688.1 - 1.2e-05 25.1 0.0 0.0031 17.3 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease US30 PF17624.2 CDO74689.1 - 1.6 7.8 4.1 2.5 7.1 4.1 1.3 1 0 0 1 1 1 0 Family of unknown function DUF659 PF04937.15 CDO74690.1 - 2e-08 34.2 0.3 4.3e-08 33.1 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) zf-RanBP PF00641.18 CDO74691.1 - 5.1e-08 32.1 14.1 1.9e-05 23.8 1.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Retrotran_gag_2 PF14223.6 CDO74693.1 - 1.4e-22 79.9 0.1 1.8e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO74693.1 - 0.13 12.4 4.8 0.37 10.9 4.8 1.8 1 1 0 1 1 1 0 Zinc knuckle AAA_32 PF13654.6 CDO74693.1 - 0.15 10.8 0.4 0.2 10.4 0.4 1.2 1 0 0 1 1 1 0 AAA domain rve PF00665.26 CDO74694.1 - 1.1e-13 51.4 0.0 1.6e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO74694.1 - 7.5e-06 25.7 0.0 3e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_2 PF07727.14 CDO74695.1 - 4.1e-67 226.3 0.0 5.9e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrolase_4 PF12146.8 CDO74696.1 - 1.4e-52 178.4 0.0 1.6e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO74696.1 - 6.4e-18 66.2 2.1 8.6e-18 65.7 2.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDO74696.1 - 6.3e-13 49.0 0.0 1.9e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDO74696.1 - 2.8e-07 30.3 0.0 0.0083 15.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Lipase_3 PF01764.25 CDO74696.1 - 0.0017 18.3 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 CDO74696.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 CDO74696.1 - 0.023 14.3 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 CDO74696.1 - 0.043 13.4 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CDO74696.1 - 0.057 13.3 0.1 0.092 12.6 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 CDO74696.1 - 0.082 11.6 0.0 24 3.4 0.0 2.9 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) PGAP1 PF07819.13 CDO74696.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 CDO74696.1 - 0.19 11.2 0.0 2.3 7.6 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pkinase_fungal PF17667.1 CDO74697.1 - 7.6e-20 71.1 0.0 1.3e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO74698.1 - 1.7e-41 142.3 0.0 1.1e-19 70.5 0.0 2.3 1 1 1 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 CDO74698.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family RRM_1 PF00076.22 CDO74699.1 - 9.1e-31 105.5 1.5 2e-09 37.2 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDO74699.1 - 3.7e-05 23.5 0.0 0.47 10.3 0.0 3.9 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CDO74699.1 - 6.7e-05 22.9 0.1 0.33 11.0 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif DUF1866 PF08952.11 CDO74699.1 - 0.00017 21.4 0.0 2.2 8.1 0.0 3.6 3 1 1 4 4 4 2 Domain of unknown function (DUF1866) RRM_5 PF13893.6 CDO74699.1 - 0.00023 20.8 0.0 0.026 14.1 0.0 2.9 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.13 CDO74699.1 - 0.0016 19.1 0.0 4.7 7.9 0.0 3.9 4 0 0 4 4 4 1 Nmi/IFP 35 domain (NID) RRM_7 PF16367.5 CDO74699.1 - 0.057 13.5 0.0 2.3 8.4 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CDO74699.1 - 0.067 13.2 0.0 4.2 7.4 0.1 3.4 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Pkinase_fungal PF17667.1 CDO74700.1 - 4e-14 52.2 0.0 7.2e-11 41.5 0.0 2.4 1 1 1 2 2 2 2 Fungal protein kinase ER_lumen_recept PF00810.18 CDO74701.1 - 1.7e-57 194.4 7.5 2.8e-57 193.7 7.5 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CDO74701.1 - 0.00016 21.4 3.6 0.44 10.3 0.0 3.9 3 1 1 4 4 4 2 PQ loop repeat Clat_adaptor_s PF01217.20 CDO74702.1 - 3.1e-18 66.1 0.0 5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mso1_Sec1_bdg PF14475.6 CDO74702.1 - 0.1 12.2 0.5 1.5 8.5 0.0 2.6 3 0 0 3 3 3 0 Sec1-binding region of Mso1 N2227 PF07942.12 CDO74703.1 - 3.8e-62 210.0 0.0 5.4e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 CDO74703.1 - 9.2e-05 22.3 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO74703.1 - 0.0028 18.4 0.0 0.01 16.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO74703.1 - 0.0049 17.5 0.1 0.25 12.0 0.0 3.0 3 1 1 4 4 4 1 Methyltransferase domain MFS_1 PF07690.16 CDO74704.1 - 6.6e-13 48.3 27.7 6.6e-13 48.3 27.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 CDO74704.1 - 1.1e-05 25.2 6.5 1.1e-05 25.2 6.5 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DIOX_N PF14226.6 CDO74705.1 - 5e-14 53.1 0.0 7.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO74705.1 - 1.4e-12 47.9 0.0 1.5e-11 44.7 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Clathrin_lg_ch PF01086.17 CDO74706.1 - 6.3e-44 150.7 2.7 7.5e-44 150.5 2.7 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF1917 PF08939.10 CDO74706.1 - 0.043 13.7 2.7 0.059 13.3 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) HAUS6_N PF14661.6 CDO74706.1 - 0.11 12.1 5.1 0.14 11.7 5.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RGS-like PF09128.11 CDO74706.1 - 0.16 11.7 1.8 0.22 11.2 1.8 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain RsbRD_N PF14361.6 CDO74706.1 - 0.24 12.1 4.0 0.38 11.5 4.0 1.4 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain TrbI_Ftype PF09677.10 CDO74706.1 - 0.25 11.7 1.0 0.42 10.9 0.9 1.4 1 1 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Endonuc_Holl PF10107.9 CDO74706.1 - 0.86 9.4 7.5 1.4 8.8 7.5 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF4407 PF14362.6 CDO74706.1 - 1.5 8.1 7.6 1.7 7.9 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L30_N PF08079.12 CDO74706.1 - 4.2 7.7 15.6 8 6.8 15.6 1.5 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain LRR_8 PF13855.6 CDO74707.1 - 4.8e-12 45.5 12.8 4.4e-05 23.2 0.5 4.3 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CDO74707.1 - 0.00019 21.7 13.1 0.026 15.0 2.3 4.2 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CDO74707.1 - 0.048 14.0 3.2 0.088 13.1 0.8 2.6 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Metallophos PF00149.28 CDO74708.1 - 1.6e-14 54.9 2.6 3e-14 54.0 2.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 CDO74708.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.7 1 1 0 1 1 1 0 5'-nucleotidase, C-terminal domain DUF218 PF02698.17 CDO74708.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 DUF218 domain Cupredoxin_1 PF13473.6 CDO74710.1 - 0.077 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain DUF3720 PF12517.8 CDO74711.1 - 0.46 11.4 4.4 0.17 12.9 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) PalH PF08733.10 CDO74711.1 - 0.48 9.4 5.7 0.69 8.9 5.7 1.3 1 0 0 1 1 1 0 PalH/RIM21 DUF4203 PF13886.6 CDO74713.1 - 6.4e-18 65.1 28.0 1.1e-17 64.4 28.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) HEAT_EZ PF13513.6 CDO74714.1 - 2.6e-30 104.4 17.2 6.1e-15 55.4 0.0 9.5 9 2 1 10 10 9 6 HEAT-like repeat HEAT PF02985.22 CDO74714.1 - 5.3e-18 63.6 11.3 0.00018 21.5 0.0 9.1 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 CDO74714.1 - 2.6e-17 63.0 0.9 7.5e-06 26.3 0.0 7.4 5 3 2 7 7 7 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CDO74714.1 - 2.2e-07 31.4 0.0 0.079 13.6 0.0 3.7 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CDO74714.1 - 2.4e-05 24.4 0.0 1.3 9.0 0.0 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CDO74714.1 - 0.00012 22.0 0.2 5.4 7.2 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 CDO74714.1 - 0.00027 20.8 1.4 1.5 8.8 0.0 4.4 5 0 0 5 5 5 2 Domain of unknown function (DUF3437) IBN_N PF03810.19 CDO74714.1 - 0.0011 18.8 0.0 0.004 17.0 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 CDO74714.1 - 0.01 14.5 0.0 0.22 10.0 0.0 2.9 3 0 0 3 3 3 0 Adaptin N terminal region Tti2 PF10521.9 CDO74714.1 - 0.015 14.9 0.6 1.7 8.1 0.1 3.7 3 2 1 4 4 4 0 Tti2 family Cohesin_HEAT PF12765.7 CDO74714.1 - 0.027 14.8 0.1 1.1e+02 3.2 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Sugar_tr PF00083.24 CDO74715.1 - 1.1e-81 275.0 0.5 1.5e-81 274.6 0.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO74715.1 - 2.8e-14 52.8 24.6 5.2e-08 32.2 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5082 PF16888.5 CDO74716.1 - 0.0016 18.7 4.0 0.025 14.8 0.4 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF5082) Med9 PF07544.13 CDO74716.1 - 0.0025 17.9 2.2 0.0025 17.9 2.2 3.3 3 1 1 4 4 3 1 RNA polymerase II transcription mediator complex subunit 9 Trimer_CC PF08954.11 CDO74716.1 - 0.012 15.1 5.1 0.059 12.9 1.5 2.9 2 0 0 2 2 2 0 Trimerisation motif DUF1664 PF07889.12 CDO74716.1 - 0.028 14.5 8.0 3.8 7.6 0.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TMCO5 PF14992.6 CDO74716.1 - 0.44 10.1 10.8 0.91 9.0 7.6 2.4 1 1 1 2 2 2 0 TMCO5 family DUF2951 PF11166.8 CDO74716.1 - 0.74 10.1 3.8 1.8 8.8 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Rab_bind PF16704.5 CDO74716.1 - 1.7 8.8 9.8 2 8.5 3.9 3.4 3 0 0 3 3 3 0 Rab binding domain Fib_alpha PF08702.10 CDO74716.1 - 2.1 8.5 10.6 15 5.8 0.7 2.9 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.11 CDO74716.1 - 2.1 8.1 5.9 5.4 6.8 5.0 2.1 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Occludin_ELL PF07303.13 CDO74716.1 - 2.2 9.1 6.6 14 6.5 0.1 3.1 3 0 0 3 3 2 0 Occludin homology domain Baculo_PEP_C PF04513.12 CDO74716.1 - 2.4 8.2 9.2 1.3 9.1 3.1 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 CDO74716.1 - 3 8.3 13.6 2.3 8.7 2.7 3.5 3 0 0 3 3 3 0 Snapin/Pallidin PI3K_P85_iSH2 PF16454.5 CDO74716.1 - 7.2 6.2 14.5 0.68 9.5 4.3 3.1 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DDE_3 PF13358.6 CDO74718.1 - 2.8e-10 40.1 0.0 6.6e-10 38.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 CDO74718.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain RVT_2 PF07727.14 CDO74719.1 - 6.9e-63 212.5 0.0 1.1e-62 211.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SelK_SelG PF10961.8 CDO74720.1 - 0.0099 16.5 0.1 0.87 10.2 0.0 2.3 1 1 1 2 2 2 2 Selenoprotein SelK_SelG Peptidase_S10 PF00450.22 CDO74722.1 - 6.6e-115 384.9 0.0 8.4e-115 384.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hyd_65N_2 PF14498.6 CDO74723.1 - 2.2e-25 89.9 0.2 5.7e-22 78.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65, N-terminal domain Pkinase PF00069.25 CDO74724.1 - 7e-53 179.7 0.0 9.9e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO74724.1 - 1.1e-19 70.7 0.2 1.8e-19 70.0 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO74724.1 - 0.0033 17.4 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDO74724.1 - 0.0038 16.9 0.9 0.0089 15.6 0.3 2.0 2 0 0 2 2 2 1 RIO1 family AAA PF00004.29 CDO74725.1 - 6.9e-37 126.8 0.0 2.1e-36 125.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.9 CDO74725.1 - 2.1e-34 118.7 0.0 3.5e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase AAA_lid_3 PF17862.1 CDO74725.1 - 8e-06 25.6 0.1 2.3e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CDO74725.1 - 0.0039 17.3 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDO74725.1 - 0.043 14.1 0.0 2.3 8.5 0.0 2.9 2 1 1 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 CDO74726.1 - 3.6e-110 366.6 0.0 5.1e-110 366.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CDO74726.1 - 9.3e-42 141.7 0.0 1.7e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CDO74726.1 - 2e-14 53.9 2.9 5.5e-14 52.4 2.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Fasciclin PF02469.22 CDO74727.1 - 3.1e-25 88.8 1.1 4.7e-13 49.5 0.0 3.9 3 1 0 3 3 3 3 Fasciclin domain DUF2793 PF10983.8 CDO74727.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2793) IPPT PF01715.17 CDO74728.1 - 2.2e-52 178.2 0.0 7.5e-52 176.4 0.0 1.7 1 1 0 1 1 1 1 IPP transferase AAA_18 PF13238.6 CDO74728.1 - 0.0008 20.0 1.3 0.084 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CDO74728.1 - 0.0084 15.7 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDO74728.1 - 0.038 14.3 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CDO74728.1 - 0.064 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 CDO74728.1 - 0.067 13.2 1.2 0.15 12.1 1.2 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 CDO74728.1 - 0.089 12.2 0.8 0.15 11.5 0.8 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase PRP38 PF03371.15 CDO74729.1 - 4e-63 212.4 0.4 4.8e-63 212.1 0.4 1.1 1 0 0 1 1 1 1 PRP38 family HEAT_2 PF13646.6 CDO74729.1 - 0.0028 18.0 0.1 0.013 15.9 0.0 2.0 2 0 0 2 2 2 1 HEAT repeats adh_short_C2 PF13561.6 CDO74730.1 - 3.8e-43 147.7 0.0 4.9e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO74730.1 - 2.6e-26 92.3 0.1 3e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase EST1_DNA_bind PF10373.9 CDO74731.1 - 4.2e-12 46.1 0.0 2.2e-10 40.5 0.0 2.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 CDO74731.1 - 5.3e-10 39.7 0.6 1.4e-09 38.3 0.6 1.7 1 0 0 1 1 1 1 PIN domain Nop14 PF04147.12 CDO74731.1 - 0.0038 15.5 5.1 0.007 14.7 5.1 1.3 1 0 0 1 1 1 1 Nop14-like family DUF2717 PF10911.8 CDO74731.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) PPP4R2 PF09184.11 CDO74731.1 - 2.8 7.5 10.8 1.4 8.5 1.4 2.5 2 0 0 2 2 2 0 PPP4R2 NDK PF00334.19 CDO74732.1 - 9.9e-53 177.8 0.0 1.4e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase UCR_14kD PF02271.16 CDO74733.1 - 5.6e-43 145.0 1.0 6.6e-43 144.8 1.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Transketolase_N PF00456.21 CDO74734.1 - 3.1e-133 443.9 0.7 1.4e-119 399.0 0.0 2.1 1 1 1 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CDO74734.1 - 2.5e-44 151.1 0.0 5.2e-44 150.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CDO74734.1 - 2.6e-10 40.2 0.0 7.1e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 CDO74734.1 - 0.00047 19.2 0.0 0.00068 18.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CDO74734.1 - 0.00059 19.1 0.0 0.00091 18.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase rve PF00665.26 CDO74736.1 - 4.2e-20 72.1 0.0 1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO74736.1 - 1.3e-11 44.3 0.0 5.4e-11 42.3 0.0 1.9 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO74736.1 - 6.3e-09 35.6 0.1 1.5e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO74736.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF4219 PF13961.6 CDO74736.1 - 2.9 7.6 6.0 13 5.6 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4219) MFS_1 PF07690.16 CDO74737.1 - 1.1e-27 96.9 15.8 1.1e-27 96.9 15.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO74737.1 - 3.4e-05 22.9 11.0 3.4e-05 22.9 11.0 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CDO74737.1 - 0.0013 17.3 13.7 0.0086 14.5 13.7 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPP1-like PF11833.8 CDO74737.1 - 2 8.0 7.2 5.9 6.5 0.0 3.2 2 1 1 4 4 4 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3180 PF11377.8 CDO74737.1 - 2.4 8.3 13.2 1.3 9.2 1.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) DUF4131 PF13567.6 CDO74737.1 - 5.3 6.7 19.1 4.9 6.8 0.6 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Pkinase_fungal PF17667.1 CDO74738.1 - 1.3e-51 175.7 0.0 2e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CDO74738.1 - 0.17 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Ysc84 PF04366.12 CDO74741.1 - 1.1e-46 157.8 0.1 1.7e-46 157.1 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Astro_capsid_p PF12226.8 CDO74743.1 - 0.0088 15.2 2.1 0.009 15.2 2.1 1.1 1 0 0 1 1 1 1 Turkey astrovirus capsid protein RVT_2 PF07727.14 CDO74744.1 - 7.7e-20 71.6 0.3 1.8e-19 70.4 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAO PF01266.24 CDO74745.1 - 3.8e-34 118.8 0.2 5.1e-34 118.4 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDO74745.1 - 0.00033 20.8 0.1 0.00084 19.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CDO74745.1 - 0.0012 18.9 0.1 0.0054 16.7 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CDO74745.1 - 0.0061 15.8 0.2 0.13 11.4 0.0 1.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO74745.1 - 0.039 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 CDO74745.1 - 0.1 11.8 0.0 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase COPI_C PF06957.11 CDO74746.1 - 0.079 11.7 0.3 0.1 11.3 0.3 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus SH3_9 PF14604.6 CDO74750.1 - 8.3e-29 99.2 2.9 8.6e-16 57.5 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CDO74750.1 - 6e-26 89.8 4.0 1.6e-14 53.2 0.4 2.3 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 CDO74750.1 - 7.5e-24 83.9 0.0 1.4e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 CDO74750.1 - 1.4e-14 53.4 0.2 3.2e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Mito_carr PF00153.27 CDO74751.1 - 6.9e-59 195.8 0.8 2.5e-22 78.6 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase_fungal PF17667.1 CDO74752.1 - 5.2e-29 101.3 0.4 3.8e-19 68.8 0.1 2.2 1 1 1 2 2 2 2 Fungal protein kinase Retrotrans_gag PF03732.17 CDO74753.1 - 4.4e-12 46.1 0.0 7.1e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO74753.1 - 5e-10 39.2 0.0 7.8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) SGTA_dimer PF16546.5 CDO74755.1 - 0.21 11.4 0.0 0.54 10.1 0.0 1.6 2 0 0 2 2 2 0 Homodimerisation domain of SGTA SWIRM-assoc_2 PF16496.5 CDO74755.1 - 0.55 9.1 2.0 0.73 8.6 2.0 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Asp_protease_2 PF13650.6 CDO74756.1 - 0.00013 22.5 0.0 0.17 12.6 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease Asp PF00026.23 CDO74756.1 - 0.011 15.2 0.0 0.57 9.6 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic aspartyl protease Retinal PF15449.6 CDO74756.1 - 0.3 8.8 3.5 0.41 8.4 3.5 1.0 1 0 0 1 1 1 0 Retinal protein F-box-like PF12937.7 CDO74758.1 - 4.8e-07 29.6 1.5 6.1e-06 26.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like WD40 PF00400.32 CDO74758.1 - 1.3e-06 29.0 0.1 0.17 12.8 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO74758.1 - 0.0021 18.3 0.1 1.7 9.0 0.0 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CDO74758.1 - 0.003 17.4 0.4 0.024 14.5 0.0 2.4 2 0 0 2 2 2 1 F-box domain Hemerythrin PF01814.23 CDO74759.1 - 0.028 15.0 2.3 0.028 15.0 2.3 1.8 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain ATG27 PF09451.10 CDO74760.1 - 3.6e-13 50.0 0.0 5.1e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 CDO74760.1 - 0.12 12.5 0.0 1.6 8.8 0.0 2.0 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat APG12 PF04110.13 CDO74761.1 - 7.8e-21 74.3 0.0 1.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 TgMIC1 PF11476.8 CDO74762.1 - 0.2 11.4 0.1 0.33 10.7 0.1 1.3 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 AMP-binding PF00501.28 CDO74763.1 - 8.9e-56 189.3 0.0 1.3e-55 188.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 CDO74763.1 - 1e-29 104.3 0.1 5.7e-29 101.9 0.1 2.1 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 CDO74763.1 - 1.1e-11 44.9 0.1 3.4e-11 43.3 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site 2OG-FeII_Oxy PF03171.20 CDO74763.1 - 1.1e-08 35.5 0.0 6e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.7 CDO74763.1 - 2.3e-05 25.1 0.5 2.3e-05 25.1 0.5 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDO74763.1 - 0.0099 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO74763.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Methyltransf_2 PF00891.18 CDO74764.1 - 3.8e-24 85.2 0.0 5e-23 81.5 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain DUF5413 PF17434.2 CDO74765.1 - 0.32 11.3 6.5 0.086 13.2 3.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5413) Hemerythrin PF01814.23 CDO74766.1 - 3e-07 31.1 1.5 3e-07 31.1 1.5 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DELLA PF12041.8 CDO74766.1 - 0.051 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal Rad10 PF03834.14 CDO74768.1 - 2.4e-47 159.7 0.0 3.4e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 CDO74768.1 - 1.7e-08 34.9 0.0 3.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 CDO74768.1 - 1.3e-06 28.4 0.0 6.8e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 CDO74768.1 - 0.0028 17.9 0.0 0.0066 16.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 CDO74768.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HhH-GPD PF00730.25 CDO74768.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Suc_Fer-like PF06999.12 CDO74769.1 - 4.1e-24 85.5 0.0 4.7e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like p450 PF00067.22 CDO74770.1 - 3e-06 26.3 0.0 3.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFAP1 PF06991.11 CDO74772.1 - 2.4e-68 230.2 27.2 2.4e-68 230.2 27.2 4.1 3 2 1 4 4 4 1 Microfibril-associated/Pre-mRNA processing zf-CCHC PF00098.23 CDO74772.1 - 0.32 11.1 0.9 0.69 10.1 0.9 1.6 1 1 0 1 1 1 0 Zinc knuckle Fasciclin PF02469.22 CDO74773.1 - 3.6e-29 101.6 4.0 1.9e-18 66.9 0.4 2.4 2 0 0 2 2 2 2 Fasciclin domain Putative_PNPOx PF01243.20 CDO74774.1 - 1.2e-06 28.6 0.0 2.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1283 PF06932.11 CDO74774.1 - 0.023 14.9 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) DUF2798 PF11391.8 CDO74774.1 - 0.13 12.3 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) Fe-S_biosyn PF01521.20 CDO74775.1 - 2.4e-22 79.2 0.0 3e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SR-25 PF10500.9 CDO74775.1 - 2.9 7.5 6.2 4 7.0 6.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MGC-24 PF05283.11 CDO74775.1 - 7.2 7.1 6.5 12 6.4 6.5 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SPRY PF00622.28 CDO74777.1 - 2.4e-23 82.5 0.1 4e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 CDO74777.1 - 2.5e-17 63.1 0.0 3.5e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CDO74777.1 - 0.0011 18.8 0.2 0.0027 17.6 0.2 1.6 1 0 0 1 1 1 1 LisH Actin PF00022.19 CDO74778.1 - 1.3e-36 126.1 0.0 8e-25 87.3 0.0 3.2 3 0 0 3 3 3 3 Actin IFP_35_N PF07334.13 CDO74778.1 - 0.22 11.6 1.7 0.55 10.3 1.7 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Ras PF00071.22 CDO74779.1 - 1.2e-62 210.3 0.0 1.4e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO74779.1 - 6.2e-34 116.8 0.1 8.7e-34 116.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO74779.1 - 2.9e-13 49.6 0.0 3.9e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDO74779.1 - 3e-05 23.7 0.0 7.5e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CDO74779.1 - 0.00012 22.1 0.0 0.00019 21.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CDO74779.1 - 0.00013 21.4 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CDO74779.1 - 0.00022 21.2 0.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CDO74779.1 - 0.0038 16.8 0.0 0.074 12.6 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 CDO74779.1 - 0.019 15.3 0.0 0.028 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 CDO74779.1 - 0.036 13.5 0.0 0.049 13.1 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 CDO74779.1 - 0.041 13.6 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 CDO74779.1 - 0.059 13.3 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 CDO74779.1 - 0.077 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Septin AAA PF00004.29 CDO74779.1 - 0.096 13.1 0.0 0.68 10.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 CDO74779.1 - 0.1 11.7 0.0 0.3 10.1 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain DOT1 PF08123.13 CDO74780.1 - 2.7e-58 196.9 0.0 2.1e-57 194.0 0.0 2.0 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 CDO74780.1 - 0.0041 17.8 0.0 0.0081 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO74780.1 - 0.0057 16.5 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO74780.1 - 0.059 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UvrD_C PF13361.6 CDO74781.1 - 4.8e-11 42.6 0.0 1.5e-08 34.4 0.0 3.2 3 1 1 4 4 4 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 CDO74781.1 - 2.5e-09 37.1 4.2 1.2e-08 34.8 0.4 3.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 CDO74781.1 - 3e-06 26.9 0.2 0.014 15.2 0.0 3.3 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CDO74781.1 - 3.9e-05 24.0 0.0 0.0003 21.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 CDO74781.1 - 0.0069 16.2 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDO74781.1 - 0.051 13.8 0.1 1.4 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_12 PF13087.6 CDO74781.1 - 0.088 12.4 0.0 0.29 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_7 PF13176.6 CDO74781.1 - 0.13 12.3 6.1 9.5 6.5 0.1 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat ResIII PF04851.15 CDO74781.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TPR_1 PF00515.28 CDO74781.1 - 1 9.3 16.4 0.61 10.0 0.8 4.8 3 1 2 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 CDO74783.1 - 2.7e-48 164.1 0.0 4.9e-48 163.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO74783.1 - 4.2e-33 114.0 0.0 6.5e-29 100.5 0.0 3.4 2 1 1 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 CDO74783.1 - 2.7e-05 23.1 0.0 0.00042 19.2 0.0 2.3 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 GREB1 PF15782.5 CDO74783.1 - 5.8 3.9 23.0 8.2 3.4 23.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAM2 PF07145.15 CDO74784.1 - 1.8 8.5 22.0 0.84 9.5 0.3 4.7 4 0 0 4 4 4 0 Ataxin-2 C-terminal region Cupin_6 PF12852.7 CDO74785.1 - 0.097 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Cupin Oxysterol_BP PF01237.18 CDO74787.1 - 9.7e-87 291.2 0.9 1.6e-84 283.9 0.9 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein SBDS_C PF09377.10 CDO74788.1 - 4.9e-34 116.8 0.0 9.2e-34 115.9 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 CDO74788.1 - 5.2e-32 109.8 0.7 8.7e-32 109.1 0.7 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein BAR PF03114.18 CDO74789.1 - 1.4e-42 146.0 1.0 1.9e-42 145.5 1.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CDO74789.1 - 4.5e-16 58.2 0.5 9.2e-16 57.2 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CDO74789.1 - 6e-15 54.8 0.1 1e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDO74789.1 - 1.2e-09 37.7 0.0 2.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.13 CDO74789.1 - 0.003 17.1 0.4 0.0056 16.3 0.0 1.6 2 0 0 2 2 2 1 Arfaptin-like domain Vps5 PF09325.10 CDO74789.1 - 0.034 13.7 6.2 0.035 13.6 3.0 2.4 2 1 0 2 2 2 0 Vps5 C terminal like zf-C4H2 PF10146.9 CDO74789.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein Glyco_trans_1_4 PF13692.6 CDO74790.1 - 8.8e-07 29.4 0.0 1.5e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 CDO74790.1 - 7.2e-05 22.4 0.0 0.00082 19.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CDO74790.1 - 0.0015 18.6 0.3 0.0048 16.9 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CDO74790.1 - 0.0016 18.9 2.5 0.0018 18.7 0.0 2.3 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CDO74790.1 - 0.0035 17.7 0.0 0.0081 16.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Nic96 PF04097.14 CDO74791.1 - 2.2e-159 531.8 0.0 2.7e-159 531.5 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF4096 PF13340.6 CDO74791.1 - 0.044 14.0 0.3 2.3 8.5 0.0 3.0 2 1 0 3 3 3 0 Putative transposase of IS4/5 family (DUF4096) ST7 PF04184.12 CDO74791.1 - 0.069 11.6 0.7 0.11 10.9 0.7 1.2 1 0 0 1 1 1 0 ST7 protein Phage_int_SAM_1 PF02899.17 CDO74791.1 - 0.14 12.5 1.7 13 6.2 0.4 2.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Cytochrom_B558a PF05038.13 CDO74792.1 - 0.051 13.1 0.3 0.087 12.4 0.3 1.3 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Pinin_SDK_N PF04697.13 CDO74792.1 - 3.3 8.4 8.3 0.28 11.8 2.9 1.9 2 0 0 2 2 2 0 pinin/SDK conserved region FYVE PF01363.21 CDO74793.1 - 9.6e-18 64.1 2.8 2.2e-17 63.0 2.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger PHD PF00628.29 CDO74795.1 - 1.4e-10 40.9 5.9 2.6e-10 40.0 5.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CDO74795.1 - 2.5e-05 23.7 2.3 2.5e-05 23.7 2.3 2.2 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 CDO74795.1 - 0.0052 16.7 2.6 0.01 15.8 2.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-CW PF07496.15 CDO74795.1 - 0.04 13.9 2.7 0.094 12.8 2.7 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger zf-PHD-like PF15446.6 CDO74795.1 - 0.11 12.1 1.8 0.26 10.9 1.8 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 CDO74795.1 - 0.44 10.8 1.7 0.83 9.9 1.7 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 CDO74795.1 - 0.57 10.1 4.5 0.11 12.5 0.9 1.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CDO74795.1 - 1 9.5 4.5 2.6 8.2 4.5 1.7 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 CDO74795.1 - 1.1 9.6 3.5 0.47 10.8 0.6 1.9 2 0 0 2 2 2 0 C1 domain DNA_methylase PF00145.17 CDO74796.1 - 3.5e-17 62.8 0.0 4.5e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Het-C PF07217.11 CDO74796.1 - 0.12 10.9 0.0 0.22 10.0 0.0 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C eIF-5_eIF-2B PF01873.17 CDO74797.1 - 1e-40 138.3 0.4 2.4e-40 137.1 0.1 1.8 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 CDO74797.1 - 5.7e-23 80.9 2.3 1.9e-22 79.2 0.0 2.8 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon UQ_con PF00179.26 CDO74798.1 - 1.6e-18 66.7 0.1 2.6e-18 66.0 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CDO74798.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain Copper-fist PF00649.18 CDO74799.1 - 8.5e-22 76.4 0.8 8.5e-22 76.4 0.8 2.2 2 0 0 2 2 2 1 Copper fist DNA binding domain HA2 PF04408.23 CDO74800.1 - 1.3e-22 80.1 4.7 2.6e-22 79.1 0.0 3.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CDO74800.1 - 4.2e-15 55.9 0.0 1.2e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CDO74800.1 - 3.7e-13 49.8 0.0 1e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDO74800.1 - 1e-08 35.2 0.0 2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDO74800.1 - 9.8e-06 25.9 0.1 4.2e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CDO74800.1 - 0.00016 21.1 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CDO74800.1 - 0.00034 20.4 0.0 0.0012 18.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CDO74800.1 - 0.0038 17.6 0.0 0.0085 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CDO74800.1 - 0.011 14.8 0.0 0.028 13.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 CDO74800.1 - 0.012 14.9 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 CDO74800.1 - 0.014 15.9 0.0 0.053 14.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 CDO74800.1 - 0.022 14.5 0.0 9.3 5.9 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein ResIII PF04851.15 CDO74800.1 - 0.024 14.7 0.4 13 5.8 0.0 3.0 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CDO74800.1 - 0.024 14.6 0.1 0.15 12.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 CDO74800.1 - 0.031 13.9 0.2 0.13 11.8 0.2 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 CDO74800.1 - 0.037 13.7 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDO74800.1 - 0.046 13.2 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 CDO74800.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CDO74800.1 - 0.13 12.7 0.3 0.47 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 CDO74800.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.0 3 1 0 3 3 2 0 AAA domain Porphobil_deam PF01379.20 CDO74801.1 - 6.3e-73 244.6 0.0 9.6e-73 244.0 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Nfu_N PF08712.11 CDO74801.1 - 1.1e-30 105.5 0.0 3.1e-30 104.1 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CDO74801.1 - 5.5e-27 93.7 0.6 1.2e-26 92.6 0.1 1.9 2 0 0 2 2 2 1 NifU-like domain Porphobil_deamC PF03900.15 CDO74801.1 - 7.1e-17 61.5 0.4 1.9e-16 60.2 0.4 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain YojJ PF10372.9 CDO74801.1 - 0.034 14.2 0.2 0.14 12.3 0.3 1.9 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus ArsA_ATPase PF02374.15 CDO74802.1 - 5.4e-108 360.8 0.4 6.5e-108 360.5 0.4 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CDO74802.1 - 2.3e-13 50.4 0.0 8.1e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 CDO74802.1 - 5.1e-11 42.7 0.0 1.3e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 CDO74802.1 - 7.7e-06 25.5 0.0 4.1e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 CDO74802.1 - 3.7e-05 23.3 2.1 0.00047 19.7 0.5 2.5 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 CDO74802.1 - 6.9e-05 22.4 0.0 0.00022 20.8 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 CDO74802.1 - 0.001 18.8 0.2 0.019 14.6 0.1 2.2 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 CDO74802.1 - 0.012 15.2 0.6 0.084 12.4 0.6 2.1 1 1 0 1 1 1 0 AAA domain SRP68 PF16969.5 CDO74803.1 - 3.9e-64 217.6 9.9 2.8e-62 211.5 6.9 2.3 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 Ribosomal_S17e PF00833.18 CDO74806.1 - 9.5e-53 177.3 0.0 1.2e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.19 CDO74807.1 - 2.2e-25 89.0 0.1 2.9e-25 88.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 SNF2_N PF00176.23 CDO74808.1 - 1.4e-72 244.3 0.5 2.8e-72 243.4 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 CDO74808.1 - 1.5e-24 85.9 1.2 3.1e-24 84.8 0.1 2.2 2 0 0 2 2 2 1 Bromodomain HSA PF07529.13 CDO74808.1 - 1.6e-19 69.9 10.9 1.6e-19 69.9 10.9 3.6 4 0 0 4 4 4 1 HSA Helicase_C PF00271.31 CDO74808.1 - 2.1e-19 69.9 0.3 3.2e-18 66.1 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain QLQ PF08880.11 CDO74808.1 - 1.3e-13 50.4 2.4 1.3e-13 50.4 0.1 2.4 2 0 0 2 2 2 1 QLQ SnAC PF14619.6 CDO74808.1 - 1.5e-12 48.0 0.9 1.5e-12 48.0 0.9 4.2 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 CDO74808.1 - 5e-12 46.2 0.1 1.9e-11 44.3 0.1 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CDO74808.1 - 1.6e-05 24.7 0.1 5e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ku PF02735.16 CDO74809.1 - 2.4e-29 102.5 0.0 4.7e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 CDO74809.1 - 3.1e-19 69.3 0.2 7.4e-19 68.1 0.2 1.6 1 0 0 1 1 1 1 Ku C terminal domain like VWA PF00092.28 CDO74809.1 - 0.00043 20.6 0.0 0.0015 18.8 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 CDO74809.1 - 0.017 15.8 0.3 0.017 15.8 0.3 2.5 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm YqhG PF11079.8 CDO74809.1 - 0.1 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function VWA_2 PF13519.6 CDO74809.1 - 0.14 12.8 0.0 0.47 11.1 0.0 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain Gp138_N PF18352.1 CDO74810.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Phage protein Gp138 N-terminal domain ABC_tran PF00005.27 CDO74811.1 - 1.9e-46 158.0 0.1 4.7e-23 82.2 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CDO74811.1 - 7e-24 83.7 3.9 7e-24 83.7 3.9 2.6 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 CDO74811.1 - 2.2e-17 63.9 10.9 0.00014 21.8 0.0 4.8 3 2 2 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDO74811.1 - 2.1e-08 33.9 0.5 0.021 14.3 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CDO74811.1 - 2e-07 31.1 0.1 0.0099 16.0 0.1 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CDO74811.1 - 4.2e-07 29.6 0.2 0.013 15.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 CDO74811.1 - 4.9e-07 30.4 0.9 0.13 12.8 0.0 4.7 4 1 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 CDO74811.1 - 3.1e-06 27.2 1.5 0.033 14.1 0.1 2.7 2 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CDO74811.1 - 4.7e-06 26.9 1.2 0.08 13.2 0.1 3.8 3 2 0 3 3 3 2 AAA domain NACHT PF05729.12 CDO74811.1 - 1.2e-05 25.3 0.1 0.2 11.6 0.0 2.7 3 0 0 3 3 2 2 NACHT domain AAA_16 PF13191.6 CDO74811.1 - 1.6e-05 25.3 5.5 0.1 12.9 0.0 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 CDO74811.1 - 9.5e-05 22.7 0.2 0.39 11.0 0.1 2.9 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 CDO74811.1 - 0.00024 20.2 0.1 0.12 11.3 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CDO74811.1 - 0.00026 20.8 0.0 0.51 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CDO74811.1 - 0.00027 21.5 14.0 0.055 14.0 0.1 4.4 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 CDO74811.1 - 0.0005 20.3 0.1 0.39 10.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 CDO74811.1 - 0.0019 18.6 0.0 0.78 10.2 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CDO74811.1 - 0.0042 17.4 0.0 2.2 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 CDO74811.1 - 0.0087 16.1 0.1 17 5.5 0.0 3.7 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 CDO74811.1 - 0.0098 15.8 0.1 2.7 7.9 0.0 2.6 2 0 0 2 2 2 1 NTPase Roc PF08477.13 CDO74811.1 - 0.016 15.4 0.0 6.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 CDO74811.1 - 0.016 14.9 0.1 3.5 7.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CDO74811.1 - 0.023 14.4 12.1 0.23 11.1 0.3 4.0 4 0 0 4 4 4 0 AAA ATPase domain AAA_5 PF07728.14 CDO74811.1 - 0.026 14.5 0.6 6.1 6.9 0.1 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CDO74811.1 - 0.036 13.2 0.1 5.3 6.1 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 CDO74811.1 - 0.038 13.6 0.2 27 4.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 CDO74811.1 - 0.044 13.3 0.0 12 5.3 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region dNK PF01712.19 CDO74811.1 - 0.056 13.3 1.1 2.3 8.0 0.0 2.8 3 0 0 3 3 3 0 Deoxynucleoside kinase PXA PF02194.15 CDO74811.1 - 0.09 12.7 1.1 0.42 10.6 0.2 2.4 3 0 0 3 3 2 0 PXA domain cobW PF02492.19 CDO74811.1 - 0.1 12.2 0.1 18 4.8 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 CDO74811.1 - 0.1 12.5 1.4 20 5.0 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea HopA1 PF17914.1 CDO74811.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 HopA1 effector protein family PduV-EutP PF10662.9 CDO74811.1 - 0.13 12.0 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 CDO74811.1 - 0.16 12.0 11.8 0.21 11.6 0.1 3.8 4 1 0 4 4 3 0 Helicase HerA, central domain Dynamin_N PF00350.23 CDO74811.1 - 0.42 10.6 5.5 0.94 9.5 0.1 3.2 4 0 0 4 4 2 0 Dynamin family Sacchrp_dh_C PF16653.5 CDO74812.1 - 1.1e-82 278.1 0.0 2e-82 277.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 CDO74812.1 - 2.9e-62 209.4 0.0 5.3e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CDO74812.1 - 1.4e-22 79.3 0.0 2.7e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Sacchrp_dh_NADP PF03435.18 CDO74812.1 - 3.3e-20 72.7 1.2 2.3e-19 70.0 0.3 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Methyltransf_25 PF13649.6 CDO74812.1 - 1.3e-07 32.2 0.0 6.8e-07 29.9 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Shikimate_DH PF01488.20 CDO74812.1 - 2e-06 27.9 0.1 2.4e-05 24.4 0.0 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_31 PF13847.6 CDO74812.1 - 2.9e-06 27.2 0.0 6.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 CDO74812.1 - 0.0001 21.7 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 CDO74812.1 - 0.00017 22.1 0.0 0.016 15.8 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO74812.1 - 0.00032 21.4 0.1 0.0023 18.7 0.0 2.6 2 1 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 CDO74812.1 - 0.0018 17.8 0.0 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain NAD_binding_7 PF13241.6 CDO74812.1 - 0.007 16.8 0.9 0.67 10.4 0.1 3.0 3 0 0 3 3 2 1 Putative NAD(P)-binding Methyltransf_18 PF12847.7 CDO74812.1 - 0.035 14.0 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2016 PF09436.10 CDO74812.1 - 0.036 13.9 0.2 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) NAD_binding_10 PF13460.6 CDO74812.1 - 0.2 11.5 0.5 0.35 10.8 0.5 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Reprolysin_2 PF13574.6 CDO74813.1 - 2.3e-43 148.4 2.0 4.2e-43 147.5 2.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CDO74813.1 - 1.2e-42 145.9 0.9 1.9e-42 145.2 0.9 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CDO74813.1 - 4.1e-41 141.3 4.9 4.1e-41 141.3 4.9 2.5 2 1 1 3 3 3 1 Metallo-peptidase family M12 Disintegrin PF00200.23 CDO74813.1 - 5.6e-17 62.3 24.6 5.6e-17 62.3 24.6 3.1 3 0 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 CDO74813.1 - 9.9e-13 48.7 0.2 4.2e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 CDO74813.1 - 5.6e-08 32.9 4.9 2.7e-07 30.7 4.9 2.1 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 CDO74813.1 - 0.0011 19.1 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M43 PF05572.13 CDO74813.1 - 0.12 12.2 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Asp PF00026.23 CDO74814.1 - 3.7e-08 33.1 0.8 4.8e-08 32.8 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Brr6_like_C_C PF10104.9 CDO74815.1 - 2.6e-43 147.0 4.8 3.4e-43 146.6 4.8 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ctr PF04145.15 CDO74815.1 - 0.043 14.4 0.3 2.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Ctr copper transporter family PBP1_TM PF14812.6 CDO74815.1 - 5.7 7.4 8.9 0.53 10.7 2.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_1 PF00515.28 CDO74817.1 - 8.3e-54 177.3 26.8 9.3e-08 31.6 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 CDO74817.1 - 4.4e-49 160.7 23.3 5.3e-05 23.0 0.1 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 CDO74817.1 - 1.1e-37 125.1 14.6 0.0059 16.7 0.8 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.6 CDO74817.1 - 3.4e-31 107.6 11.6 3.7e-09 37.1 0.0 6.9 5 1 3 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 CDO74817.1 - 1.1e-29 100.5 14.7 0.00041 20.9 0.0 10.3 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 CDO74817.1 - 4.4e-25 86.2 11.8 0.00049 20.3 0.0 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 CDO74817.1 - 1.7e-23 82.9 18.2 0.00017 22.0 1.9 7.2 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 CDO74817.1 - 9.8e-23 80.2 23.4 2.8e-05 24.3 1.9 8.0 5 3 3 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 CDO74817.1 - 6.6e-21 73.7 32.7 1.1e-05 25.0 0.1 9.6 6 3 3 9 9 9 5 TPR repeat TPR_7 PF13176.6 CDO74817.1 - 7.3e-21 72.6 11.2 0.051 13.6 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 CDO74817.1 - 1.1e-20 72.8 16.6 0.005 17.4 0.0 9.9 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 CDO74817.1 - 1.1e-13 51.1 14.9 0.035 14.2 0.1 6.9 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_21 PF09976.9 CDO74817.1 - 4.7e-08 33.0 2.8 0.0036 17.0 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 CDO74817.1 - 8e-08 32.4 9.9 2e-05 24.7 0.8 4.0 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CDO74817.1 - 1.8e-07 30.7 10.2 1.5 7.9 0.1 5.8 1 1 5 6 6 6 3 Tetratricopeptide repeat SNAP PF14938.6 CDO74817.1 - 0.00024 20.7 11.2 0.34 10.3 1.6 4.4 1 1 3 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 CDO74817.1 - 0.00064 19.2 2.0 0.0017 17.8 0.5 2.3 1 1 1 2 2 2 1 MalT-like TPR region DUF2225 PF09986.9 CDO74817.1 - 0.0032 17.2 2.3 1.2 8.8 0.1 3.5 2 2 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.9 CDO74817.1 - 0.0069 16.1 0.3 13 5.5 0.0 4.0 2 2 2 4 4 4 0 26S proteasome subunit RPN7 ChAPs PF09295.10 CDO74817.1 - 0.0088 15.1 0.3 5.6 5.9 0.0 2.5 2 1 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 CDO74817.1 - 0.058 13.5 0.1 57 3.9 0.0 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 CDO74817.1 - 0.061 14.0 0.1 32 5.4 0.0 3.2 2 0 0 2 2 2 0 Sel1 repeat TPR_10 PF13374.6 CDO74817.1 - 0.13 12.1 14.4 0.59 10.1 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 CDO74817.1 - 0.16 12.4 5.6 0.37 11.2 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 CDO74817.1 - 6.9 6.8 26.3 8.9 6.4 2.7 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 CDO74817.1 - 9.9 6.3 23.6 19 5.4 0.0 6.3 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain Erf4 PF10256.9 CDO74818.1 - 4.9e-31 107.2 0.0 6.8e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ATPase_2 PF01637.18 CDO74821.1 - 7.8e-07 29.2 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CDO74821.1 - 4.5e-06 27.1 0.0 9.7e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDO74821.1 - 0.011 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CDO74821.1 - 0.043 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 CDO74822.1 - 7.2e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea ResIII PF04851.15 CDO74822.1 - 0.037 14.0 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Piwi PF02171.17 CDO74823.1 - 7.7e-85 284.8 0.0 1.2e-84 284.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CDO74823.1 - 6e-27 94.9 0.0 1.2e-26 94.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CDO74823.1 - 1.7e-20 72.5 0.1 4.2e-20 71.1 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CDO74823.1 - 1.4e-12 47.7 0.1 4.9e-12 46.0 0.1 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 CDO74823.1 - 4.8e-07 29.7 0.0 0.0017 18.2 0.0 2.4 2 0 0 2 2 2 2 PAZ domain ArgoMid PF16487.5 CDO74823.1 - 0.0016 18.7 0.0 0.0042 17.3 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute Pkinase PF00069.25 CDO74826.1 - 3.7e-37 128.1 0.0 4.7e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO74826.1 - 7.1e-17 61.5 0.0 1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO74826.1 - 0.00016 21.7 0.8 0.00034 20.6 0.8 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDO74826.1 - 0.00053 19.4 0.1 0.0009 18.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDO74826.1 - 0.0017 17.2 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDO74826.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Thr_synth_N PF14821.6 CDO74827.1 - 2.5e-26 91.7 0.0 6.5e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 CDO74827.1 - 4.2e-15 55.9 0.0 1.1e-14 54.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF659 PF04937.15 CDO74828.1 - 8.4e-07 29.0 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CDO74828.1 - 0.045 13.5 0.1 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region WD40 PF00400.32 CDO74829.1 - 5.1e-36 122.1 23.1 6.1e-07 30.0 0.0 8.0 7 1 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 CDO74829.1 - 1.6e-10 40.7 3.3 3.2e-10 39.7 3.3 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 CDO74829.1 - 9.2e-09 34.5 2.0 0.0048 15.6 0.0 4.2 2 1 2 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.33 CDO74829.1 - 2e-08 33.9 2.1 4.8e-08 32.7 2.1 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 CDO74829.1 - 2.4e-07 31.0 0.0 0.066 13.5 0.0 4.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDO74829.1 - 0.00057 19.3 0.0 0.47 9.7 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain Nucleoporin_N PF08801.11 CDO74829.1 - 0.047 12.4 0.1 9.9 4.8 0.0 3.5 3 1 1 4 4 4 0 Nup133 N terminal like Ge1_WD40 PF16529.5 CDO74829.1 - 0.18 10.7 0.1 18 4.1 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AMP-binding PF00501.28 CDO74830.1 - 4.3e-52 177.1 0.1 5.5e-52 176.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDO74830.1 - 3e-14 53.8 0.1 5.7e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain rve PF00665.26 CDO74831.1 - 2.4e-14 53.5 0.0 4.5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO74831.1 - 2.4e-07 30.5 0.1 4.6e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 CDO74831.1 - 0.12 12.1 0.4 0.55 10.1 0.0 2.2 3 0 0 3 3 3 0 Integrase core domain zf-C2H2 PF00096.26 CDO74833.1 - 0.0025 18.2 1.5 0.0025 18.2 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type O-FucT PF10250.9 CDO74834.1 - 8.2e-08 32.3 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RhoGEF PF00621.20 CDO74835.1 - 2.8e-35 122.2 0.0 4.7e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Ribosomal_S15 PF00312.22 CDO74835.1 - 3.6e-15 55.9 1.3 6.8e-15 55.0 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S15 PH PF00169.29 CDO74835.1 - 0.00037 21.0 0.0 0.0013 19.2 0.0 1.9 2 0 0 2 2 2 1 PH domain MMR_HSR1 PF01926.23 CDO74836.1 - 1.2e-18 67.3 0.2 4.6e-14 52.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase NGP1NT PF08153.12 CDO74836.1 - 1.5e-09 38.1 0.0 4.3e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 NGP1NT (NUC091) domain FeoB_N PF02421.18 CDO74836.1 - 6e-07 29.1 0.8 3.3e-05 23.4 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDO74836.1 - 2.8e-05 23.7 0.0 0.0023 17.5 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDO74836.1 - 3e-05 24.0 0.0 9.2e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 CDO74836.1 - 0.00042 19.8 0.0 0.16 11.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CDO74836.1 - 0.025 14.8 0.1 6 7.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CDO74836.1 - 0.43 10.6 6.9 7 6.7 0.1 3.9 3 1 1 4 4 4 0 Dynamin family Glyco_hydro_31 PF01055.26 CDO74837.1 - 1e-132 443.5 4.2 1.4e-132 443.1 4.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CDO74837.1 - 6.2e-29 100.5 0.0 1.1e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 CDO74837.1 - 3.8e-05 23.9 0.4 0.00021 21.5 0.1 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like Rotavirus_VP7 PF05868.11 CDO74837.1 - 0.0087 15.5 0.5 0.015 14.7 0.5 1.3 1 0 0 1 1 1 1 Rotavirus major outer capsid protein VP7 MEA1 PF06910.11 CDO74838.1 - 0.07 13.8 1.2 0.11 13.1 0.0 1.8 2 0 0 2 2 2 0 Male enhanced antigen 1 (MEA1) Pga1 PF10333.9 CDO74839.1 - 8.6e-05 22.5 0.7 0.0017 18.2 0.2 2.6 2 1 0 2 2 2 1 GPI-Mannosyltransferase II co-activator SAP PF02037.27 CDO74842.1 - 1.2e-08 34.5 0.5 2.2e-08 33.7 0.5 1.3 1 0 0 1 1 1 1 SAP domain CybS PF05328.12 CDO74844.1 - 8.1e-44 148.5 0.0 1e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit APH PF01636.23 CDO74845.1 - 3e-06 27.3 2.0 6.4e-06 26.3 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family TFIIA_gamma_N PF02268.16 CDO74846.1 - 7.2e-25 86.7 0.1 1.1e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 CDO74846.1 - 2e-23 82.3 0.1 3.3e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF2781 PF10914.8 CDO74847.1 - 1.7e-43 148.5 10.4 2.4e-43 148.1 10.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DSPc PF00782.20 CDO74848.1 - 0.00012 21.8 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDO74848.1 - 0.00029 20.9 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CDO74848.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDO74848.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate RPN1_RPN2_N PF17781.1 CDO74850.1 - 1e-115 386.4 0.0 1.5e-115 385.9 0.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CDO74850.1 - 1.3e-30 105.1 0.1 2.9e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CDO74850.1 - 2.4e-27 93.9 21.4 1.5e-07 31.5 0.1 9.1 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CDO74850.1 - 7.9e-07 29.4 0.3 0.59 10.6 0.0 5.0 5 2 0 5 5 5 2 HEAT repeats DUF1039 PF06287.11 CDO74850.1 - 1.1 9.7 3.3 8 7.0 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1039) OAD_gamma PF04277.13 CDO74850.1 - 9.3 6.9 9.7 24 5.6 0.0 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4263 PF14082.6 CDO74851.1 - 0.2 11.9 0.1 0.2 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) DUF5542 PF17696.1 CDO74851.1 - 8.6 6.6 5.6 15 5.8 4.7 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5542) 2Fe-2S_thioredx PF01257.19 CDO74854.1 - 0.1 12.5 0.3 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin PET PF06297.14 CDO74855.1 - 0.25 11.7 4.0 1 9.7 0.0 3.0 2 1 1 3 3 3 0 PET Domain Transposase_21 PF02992.14 CDO74857.1 - 5.6e-28 97.7 0.2 1.5e-27 96.2 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 CDO74857.1 - 0.031 13.9 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF2009 PF09418.10 CDO74857.1 - 0.19 10.8 0.3 0.59 9.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2009) Glyco_hydro_3_C PF01915.22 CDO74858.1 - 2.5e-58 197.4 0.0 3.8e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CDO74858.1 - 3.2e-24 84.8 0.1 6.9e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 CDO74858.1 - 2.5e-21 76.4 0.0 6.9e-19 68.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 CDO74858.1 - 2.6e-12 46.8 0.0 4.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 PA14 domain DUF11 PF01345.18 CDO74858.1 - 0.016 15.5 1.1 0.76 10.1 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function DUF11 DUF2340 PF10209.9 CDO74859.1 - 6.3e-53 178.3 1.4 7.1e-53 178.1 1.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 CDO74859.1 - 0.026 14.8 0.0 0.031 14.6 0.0 1.1 1 0 0 1 1 1 0 Blt1 N-terminal domain Ubiquitin_4 PF18036.1 CDO74859.1 - 0.051 13.6 0.6 1 9.5 0.0 2.5 2 1 0 2 2 2 0 Ubiquitin-like domain UAE_UbL PF14732.6 CDO74859.1 - 0.084 13.5 0.4 0.34 11.5 0.4 1.9 1 1 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Mis14 PF08641.12 CDO74860.1 - 5.4e-08 33.2 7.8 1e-07 32.3 7.8 1.5 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Nefa_Nip30_N PF10187.9 CDO74860.1 - 0.033 14.5 4.0 0.069 13.5 4.0 1.6 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2451 PF10474.9 CDO74860.1 - 0.091 12.5 0.3 9.3 6.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) Gar1 PF04410.14 CDO74861.1 - 8.9e-38 129.5 0.0 1.2e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA PF00004.29 CDO74862.1 - 4.9e-54 182.3 0.0 3.1e-44 150.6 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDO74862.1 - 3.2e-10 39.7 7.4 5.7e-05 22.8 0.2 3.4 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 CDO74862.1 - 2.7e-08 34.4 0.9 0.0098 16.3 0.0 4.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 CDO74862.1 - 6.2e-06 26.3 0.1 0.027 14.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDO74862.1 - 6.6e-06 26.0 0.0 0.0073 16.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CDO74862.1 - 1.1e-05 25.8 0.1 0.15 12.3 0.1 3.9 3 1 1 4 4 4 1 AAA domain TIP49 PF06068.13 CDO74862.1 - 3.2e-05 23.3 0.0 0.054 12.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_25 PF13481.6 CDO74862.1 - 0.00081 19.0 0.1 0.0072 15.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDO74862.1 - 0.0014 18.4 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 CDO74862.1 - 0.0018 18.2 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CDO74862.1 - 0.0024 18.4 0.0 0.094 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDO74862.1 - 0.003 17.1 0.0 0.049 13.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CDO74862.1 - 0.0032 17.2 0.0 0.66 9.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase PF06745.13 CDO74862.1 - 0.0034 16.8 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.6 CDO74862.1 - 0.0051 17.0 0.0 0.78 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CDO74862.1 - 0.0064 16.6 0.0 0.18 11.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CDO74862.1 - 0.0083 15.5 0.1 0.066 12.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CDO74862.1 - 0.0095 16.0 0.0 2.2 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDO74862.1 - 0.014 15.8 0.0 0.21 12.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Vps4_C PF09336.10 CDO74862.1 - 0.016 15.2 0.0 0.31 11.1 0.0 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain PhoH PF02562.16 CDO74862.1 - 0.038 13.4 0.0 0.095 12.1 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein Parvo_NS1 PF01057.17 CDO74862.1 - 0.045 12.9 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 CDO74862.1 - 0.057 13.1 0.1 0.53 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CDO74862.1 - 0.065 12.4 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 CDO74862.1 - 0.071 12.8 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_11 PF13086.6 CDO74862.1 - 0.094 12.5 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 CDO74862.1 - 0.1 11.6 0.0 11 4.9 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_28 PF13521.6 CDO74862.1 - 0.16 12.2 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 CDO74862.1 - 0.17 11.8 0.0 0.88 9.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CDO74862.1 - 0.21 11.5 0.2 14 5.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain PhoD PF09423.10 CDO74863.1 - 1.1e-33 116.7 0.0 4.7e-33 114.7 0.0 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 CDO74863.1 - 0.019 15.5 2.0 0.041 14.4 0.1 2.5 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 CDO74863.1 - 0.023 15.3 2.7 0.025 15.2 0.0 2.5 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Ufm1 PF03671.14 CDO74863.1 - 0.065 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein FH2 PF02181.23 CDO74864.1 - 6.9e-74 249.2 5.0 6.9e-74 249.2 5.0 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CDO74864.1 - 2.3e-36 125.1 0.5 7e-36 123.6 0.1 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CDO74864.1 - 1.9e-33 115.7 0.1 6.1e-33 114.1 0.1 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF148 PF02520.17 CDO74864.1 - 0.0044 17.1 0.9 0.09 12.9 0.3 3.1 2 0 0 2 2 2 1 Domain of unknown function DUF148 CENP-F_leu_zip PF10473.9 CDO74864.1 - 0.0064 16.5 1.5 0.0064 16.5 1.5 3.4 4 0 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin_2 PF14523.6 CDO74864.1 - 0.032 14.6 0.0 0.032 14.6 0.0 3.5 4 0 0 4 4 4 0 Syntaxin-like protein Fib_alpha PF08702.10 CDO74864.1 - 0.068 13.4 3.1 42 4.3 0.1 4.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family SPOUT_MTase_2 PF14419.6 CDO74864.1 - 0.15 11.4 0.1 0.35 10.2 0.1 1.5 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP DBR1 PF05011.13 CDO74864.1 - 0.34 11.3 1.8 1.1 9.6 0.4 2.6 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain Leu_zip PF15294.6 CDO74864.1 - 1.1 8.8 14.9 0.12 11.9 0.3 3.3 3 0 0 3 3 3 0 Leucine zipper ERAP1_C PF11838.8 CDO74865.1 - 4e-70 236.9 2.6 7.5e-70 236.0 2.6 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CDO74865.1 - 1.5e-58 198.0 0.2 2.7e-58 197.1 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CDO74865.1 - 5.2e-42 144.2 0.1 1.4e-40 139.5 0.0 2.6 2 1 0 2 2 2 1 Peptidase M1 N-terminal domain PRP3 PF08572.10 CDO74865.1 - 0.19 11.4 0.1 0.39 10.4 0.1 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) HECT PF00632.25 CDO74866.1 - 3.8e-93 312.3 0.0 9e-93 311.1 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CDO74866.1 - 2.3e-36 123.5 15.5 3.8e-12 46.1 1.6 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.30 CDO74866.1 - 1.3e-17 63.9 0.1 4.2e-17 62.3 0.1 1.8 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.13 CDO74866.1 - 2 8.3 11.4 3.1 7.7 11.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box-like PF12937.7 CDO74867.1 - 8.1e-07 28.8 0.2 2.7e-06 27.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 CDO74868.1 - 3.6e-11 42.8 0.1 1e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDO74868.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain Far-17a_AIG1 PF04750.14 CDO74869.1 - 6.1e-06 25.7 13.1 9.1e-06 25.1 13.1 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pox_MCEL PF03291.16 CDO74870.1 - 2.9e-84 283.0 0.0 4.4e-84 282.4 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CDO74870.1 - 3.6e-14 53.2 0.0 6.7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO74870.1 - 2.2e-11 43.8 0.0 3.7e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO74870.1 - 5.5e-11 43.1 0.0 1.1e-10 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO74870.1 - 5.7e-11 42.5 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO74870.1 - 7.2e-09 36.2 0.0 1.4e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CDO74870.1 - 0.003 17.0 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NNMT_PNMT_TEMT PF01234.17 CDO74870.1 - 0.0048 16.1 0.0 0.0074 15.5 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.14 CDO74870.1 - 0.0066 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Rhodanese PF00581.20 CDO74871.1 - 2.8e-14 53.5 0.0 7.3e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DJ-1_PfpI PF01965.24 CDO74872.1 - 4.2e-12 46.2 0.0 9.8e-12 45.0 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CDO74872.1 - 5.8e-12 45.7 0.0 7.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 CDO74872.1 - 0.022 14.3 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Lipase_GDSL_2 PF13472.6 CDO74873.1 - 3.6e-27 95.9 0.0 5.7e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CDO74873.1 - 1.2e-21 77.7 0.0 1.5e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase F-box-like PF12937.7 CDO74874.1 - 2.8e-06 27.1 0.3 6.9e-06 25.9 0.3 1.7 1 0 0 1 1 1 1 F-box-like ATP12 PF07542.11 CDO74875.1 - 3e-34 117.9 0.2 1e-32 112.9 0.0 2.8 2 1 0 2 2 2 1 ATP12 chaperone protein MutS_V PF00488.21 CDO74876.1 - 2.3e-55 187.6 0.0 5e-55 186.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CDO74876.1 - 2.6e-36 125.6 0.4 1e-35 123.7 0.4 2.1 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CDO74876.1 - 1.3e-11 44.7 0.0 2.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CDO74876.1 - 2.3e-10 40.9 0.0 7.2e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CDO74876.1 - 2e-05 24.8 0.4 5e-05 23.6 0.4 1.7 1 0 0 1 1 1 1 MutS family domain IV DNA_pol_phi PF04931.13 CDO74877.1 - 2.4e-245 816.3 19.8 2.4e-245 816.3 19.8 1.6 2 0 0 2 2 2 1 DNA polymerase phi RPA_interact_N PF14766.6 CDO74877.1 - 0.1 12.3 0.2 0.33 10.6 0.2 1.9 1 0 0 1 1 1 0 Replication protein A interacting N-terminal EI24 PF07264.11 CDO74879.1 - 3.1e-36 125.3 18.0 5.4e-36 124.5 18.0 1.4 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Lipase_GDSL_2 PF13472.6 CDO74879.1 - 0.00016 22.2 0.0 0.0013 19.2 0.0 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family BTB PF00651.31 CDO74879.1 - 0.0052 17.0 0.0 0.0096 16.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF4349 PF14257.6 CDO74879.1 - 0.061 12.8 0.5 0.14 11.6 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CDK2AP PF09806.9 CDO74880.1 - 0.28 11.2 6.2 0.52 10.3 6.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Ndc1_Nup PF09531.10 CDO74880.1 - 5.6 5.5 7.5 7.3 5.2 7.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glycos_transf_1 PF00534.20 CDO74881.1 - 3e-20 72.4 0.0 5.3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDO74881.1 - 2.4e-12 47.5 0.0 4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CDO74881.1 - 1.5e-05 25.3 0.0 3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 TF_Zn_Ribbon PF08271.12 CDO74882.1 - 0.0063 16.0 0.4 0.015 14.8 0.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.19 CDO74882.1 - 0.019 15.0 0.1 0.046 13.8 0.1 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat zf-RRN7 PF11781.8 CDO74882.1 - 0.07 12.8 0.4 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 tRNA_int_endo PF01974.17 CDO74883.1 - 1.9e-16 59.9 0.0 4.7e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Rrn6 PF10214.9 CDO74883.1 - 0.012 14.1 2.0 0.015 13.8 2.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Pkinase_fungal PF17667.1 CDO74884.1 - 3.3e-46 157.9 0.1 3.6e-33 114.9 0.1 2.8 2 1 0 2 2 2 2 Fungal protein kinase 2OG-FeII_Oxy_2 PF13532.6 CDO74885.1 - 1e-26 94.3 0.0 1.5e-25 90.6 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LETM1 PF07766.13 CDO74886.1 - 1.3e-104 349.3 0.7 1.3e-104 349.3 0.7 2.0 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 CDO74886.1 - 1.2e-05 24.9 0.0 0.0031 17.2 0.0 3.7 3 0 0 3 3 3 1 SAP domain EF-hand_7 PF13499.6 CDO74886.1 - 0.00036 20.9 2.3 0.011 16.1 0.1 3.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CDO74886.1 - 0.00068 19.0 0.3 0.13 11.9 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 CDO74886.1 - 0.0018 18.1 0.0 7.4 6.8 0.0 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CDO74886.1 - 0.0019 18.0 0.0 0.027 14.3 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CDO74886.1 - 0.011 15.2 0.2 5.2 6.7 0.0 3.3 3 0 0 3 3 3 0 EF hand eIF-5a PF01287.20 CDO74886.1 - 0.074 13.2 1.3 3 8.0 0.1 2.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF1682 PF07946.14 CDO74886.1 - 0.21 10.8 7.0 0.41 9.8 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_S46 PF10459.9 CDO74886.1 - 1.4 7.5 6.0 2 7.0 6.0 1.2 1 0 0 1 1 1 0 Peptidase S46 DALR_1 PF05746.15 CDO74886.1 - 2.3 8.4 7.4 7.6 6.7 5.5 2.6 2 0 0 2 2 2 0 DALR anticodon binding domain BTB PF00651.31 CDO74887.1 - 0.0043 17.3 0.0 0.072 13.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF3530 PF12048.8 CDO74889.1 - 0.26 10.7 9.7 0.54 9.6 9.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) FAM176 PF14851.6 CDO74889.1 - 0.3 10.8 8.5 0.068 12.8 3.4 2.1 2 0 0 2 2 2 0 FAM176 family Atrophin-1 PF03154.15 CDO74889.1 - 0.63 8.3 9.6 0.79 7.9 9.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family FancD2 PF14631.6 CDO74889.1 - 1.9 5.8 5.7 2.8 5.2 5.7 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease PA26 PF04636.13 CDO74889.1 - 2.2 7.1 4.3 2.7 6.8 4.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DNA_pol_phi PF04931.13 CDO74889.1 - 2.8 5.9 9.1 3.2 5.8 9.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Serinc PF03348.15 CDO74889.1 - 3.7 6.4 3.3 4.4 6.1 3.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) V_ATPase_I PF01496.19 CDO74889.1 - 4.5 5.1 5.7 5.6 4.8 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paf1 PF03985.13 CDO74889.1 - 6.1 5.7 20.2 0.092 11.7 12.7 1.7 2 0 0 2 2 2 0 Paf1 BSP_II PF05432.11 CDO74889.1 - 8 6.1 31.7 7.8 6.1 21.5 1.5 1 1 1 2 2 2 0 Bone sialoprotein II (BSP-II) DUF4551 PF15087.6 CDO74889.1 - 8.4 5.1 6.8 7.8 5.2 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Plavaka PF18759.1 CDO74891.1 - 2.8e-121 404.7 0.0 3.9e-121 404.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase RVT_1 PF00078.27 CDO74892.1 - 4.5e-35 121.2 0.0 7.7e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO74892.1 - 2.8e-18 65.9 0.0 8.4e-18 64.3 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDO74892.1 - 3.7e-09 36.5 1.1 3.7e-09 36.5 1.1 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family ORC4_C PF14629.6 CDO74893.1 - 0.052 12.9 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus PAS_4 PF08448.10 CDO74893.1 - 0.14 12.4 0.0 0.45 10.8 0.0 1.8 2 0 0 2 2 2 0 PAS fold RVT_2 PF07727.14 CDO74894.1 - 1.3e-67 228.0 2.2 2.4e-67 227.1 1.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO74894.1 - 3.4e-19 69.2 0.0 7.8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO74894.1 - 7e-08 32.2 0.2 2.4e-05 24.0 0.2 3.1 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 CDO74894.1 - 0.00033 20.4 0.0 0.00081 19.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO74894.1 - 0.13 12.1 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain RVT_1 PF00078.27 CDO74895.1 - 8.1e-21 74.6 0.0 1.4e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO74895.1 - 1e-08 35.4 0.0 4.2e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 RNase H Exo_endo_phos_2 PF14529.6 CDO74895.1 - 2.4e-08 33.8 0.0 5.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 CDO74895.1 - 1.1e-05 26.0 0.1 0.00014 22.5 0.0 2.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CDO74895.1 - 0.048 13.2 0.4 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family HIP1_clath_bdg PF16515.5 CDO74895.1 - 0.28 11.8 6.0 0.23 12.1 3.8 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF724 PF05266.14 CDO74895.1 - 0.34 10.7 0.6 1.3 8.8 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) zf-CCHC PF00098.23 CDO74895.1 - 0.72 10.0 2.0 2.3 8.4 2.0 2.0 1 0 0 1 1 1 0 Zinc knuckle ARGLU PF15346.6 CDO74895.1 - 1.9 8.4 5.8 3.6 7.4 5.8 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 THOC7 PF05615.13 CDO74895.1 - 4.1 7.7 5.4 0.91 9.8 1.1 2.1 3 0 0 3 3 3 0 Tho complex subunit 7 His_Phos_2 PF00328.22 CDO74897.1 - 4e-30 105.4 0.0 4.8e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Rtt106_N PF18215.1 CDO74898.1 - 0.15 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone chaperone Rtt106 N-terminal domain Zip PF02535.22 CDO74899.1 - 6.8e-38 130.7 5.6 6.8e-38 130.7 5.6 1.6 2 0 0 2 2 2 1 ZIP Zinc transporter THUMP PF02926.17 CDO74900.1 - 2.9e-08 33.9 0.4 6.5e-08 32.8 0.4 1.6 1 0 0 1 1 1 1 THUMP domain HD PF01966.22 CDO74900.1 - 0.051 13.8 0.2 0.34 11.2 0.1 2.4 3 0 0 3 3 3 0 HD domain F_actin_cap_B PF01115.17 CDO74901.1 - 2.4e-108 361.3 0.0 2.8e-108 361.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit G-alpha PF00503.20 CDO74902.1 - 1.7e-104 349.8 0.0 6.4e-104 347.9 0.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDO74902.1 - 1.2e-08 34.6 0.1 6.6e-05 22.4 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CDO74902.1 - 0.045 14.0 0.0 6.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CDO74902.1 - 0.048 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 CDO74902.1 - 0.049 13.0 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 CDO74902.1 - 0.11 12.3 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pro_isomerase PF00160.21 CDO74903.1 - 6.3e-23 81.8 0.0 7.1e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_N PF00339.29 CDO74904.1 - 1.6e-05 25.0 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CDO74904.1 - 0.00027 21.4 0.0 0.42 11.1 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain ANAPC4_WD40 PF12894.7 CDO74904.1 - 0.0011 19.3 0.0 0.018 15.3 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDO74904.1 - 0.025 15.5 9.9 8.1 7.5 0.1 6.2 7 0 0 7 7 7 0 WD domain, G-beta repeat SH3_9 PF14604.6 CDO74905.1 - 0.00011 21.9 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CDO74905.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 SH3 domain LapA_dom PF06305.11 CDO74906.1 - 0.001 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Amnionless PF14828.6 CDO74906.1 - 0.0018 17.2 0.8 0.0025 16.7 0.0 1.5 2 0 0 2 2 2 1 Amnionless Mid2 PF04478.12 CDO74906.1 - 0.0019 18.0 0.0 0.0057 16.5 0.0 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF1206 PF06724.11 CDO74906.1 - 0.019 15.1 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) SARAF PF06682.12 CDO74906.1 - 0.031 13.9 0.1 0.031 13.9 0.1 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Shisa PF13908.6 CDO74906.1 - 0.035 14.3 0.1 0.035 14.3 0.1 2.8 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 CDO74906.1 - 0.04 14.8 0.6 0.11 13.4 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain 7tm_1 PF00001.21 CDO74906.1 - 0.043 13.1 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Rhabdo_glycop PF00974.18 CDO74906.1 - 0.18 10.2 0.1 0.27 9.6 0.1 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein WBP-1 PF11669.8 CDO74906.1 - 0.23 12.1 1.0 0.69 10.6 0.1 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 PRIMA1 PF16101.5 CDO74906.1 - 0.26 11.3 0.1 0.26 11.3 0.1 2.9 3 1 0 3 3 3 0 Proline-rich membrane anchor 1 SKG6 PF08693.10 CDO74906.1 - 0.43 10.0 7.1 0.97 8.9 7.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Fungal_trans PF04082.18 CDO74907.1 - 5.8e-11 41.9 0.0 1.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CDO74907.1 - 8e-05 22.7 9.7 0.00015 21.8 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.23 CDO74908.1 - 6.7e-48 163.7 20.4 4.1e-29 102.1 8.9 3.2 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 CDO74908.1 - 9.6e-46 155.7 0.1 8.1e-30 104.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDO74908.1 - 2.3e-07 30.5 0.3 0.00063 19.3 0.2 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CDO74908.1 - 0.019 15.0 0.1 0.052 13.6 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 CDO74908.1 - 0.033 14.0 0.9 3.2 7.5 0.4 2.7 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 CDO74908.1 - 0.075 11.7 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain C2 PF00168.30 CDO74909.1 - 2.8e-13 50.0 0.1 4.8e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 C2 domain CCDC50_N PF15295.6 CDO74909.1 - 0.17 12.1 9.3 0.29 11.3 9.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Sad1_UNC PF07738.13 CDO74910.1 - 2.7e-16 59.8 0.0 1.4e-09 38.1 0.0 2.6 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal Spc7 PF08317.11 CDO74910.1 - 0.0092 14.9 3.1 0.018 14.0 3.1 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein TRAF_BIRC3_bd PF16673.5 CDO74910.1 - 0.024 14.4 0.8 3.5 7.5 0.0 2.7 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain TACC_C PF05010.14 CDO74910.1 - 0.027 14.3 2.0 0.057 13.2 2.0 1.5 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1980 PF09323.10 CDO74910.1 - 0.29 11.0 0.4 0.64 9.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Seryl_tRNA_N PF02403.22 CDO74910.1 - 0.84 9.9 3.8 2.7 8.3 3.8 1.9 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DnaJ_C PF01556.18 CDO74911.1 - 3.7e-37 127.7 0.1 4.7e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CDO74911.1 - 4.2e-11 43.0 16.9 6.9e-11 42.4 16.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CDO74911.1 - 0.018 15.0 18.2 0.1 12.6 5.8 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CDO74911.1 - 0.021 14.8 8.7 0.7 9.9 2.7 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CDO74911.1 - 4.4 7.4 9.3 3.5 7.7 2.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon Methyltr_RsmB-F PF01189.17 CDO74912.1 - 1.2e-18 67.5 0.1 4.6e-17 62.3 0.1 2.3 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F SF1-HH PF16275.5 CDO74913.1 - 5.3e-39 133.0 1.8 5.3e-39 133.0 1.8 1.9 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 CDO74913.1 - 1.2e-11 44.2 8.9 1.5e-05 24.8 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CDO74913.1 - 7.2e-07 29.1 3.6 0.0028 17.6 1.4 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 CDO74913.1 - 1.2e-06 28.2 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.6 CDO74913.1 - 0.0014 18.4 5.2 0.57 10.1 0.9 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 CDO74913.1 - 0.0063 16.2 7.1 0.43 10.3 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle CCDC-167 PF15188.6 CDO74913.1 - 0.0081 16.5 2.9 1.9 8.9 0.2 2.4 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 167 Acyl-CoA_ox_N PF14749.6 CDO74913.1 - 0.14 12.7 1.7 0.46 11.0 0.6 2.1 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal DnaJ_CXXCXGXG PF00684.19 CDO74913.1 - 0.17 12.3 4.5 0.4 11.1 4.5 1.6 1 0 0 1 1 1 0 DnaJ central domain Prim_Zn_Ribbon PF08273.12 CDO74913.1 - 0.27 11.6 3.6 0.59 10.5 3.6 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-CCHC_2 PF13696.6 CDO74913.1 - 4.2 7.3 9.8 0.38 10.6 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle ERCC3_RAD25_C PF16203.5 CDO74914.1 - 2e-123 410.4 0.0 4.4e-123 409.3 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CDO74914.1 - 1.1e-29 103.1 0.0 2.6e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO74914.1 - 2.8e-17 63.3 0.0 6.1e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDO74914.1 - 4.8e-12 46.2 0.2 2.7e-11 43.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CDO74914.1 - 9.4e-10 37.7 0.1 1.2e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CDO74914.1 - 1.2e-05 25.1 0.1 2.2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cys_Met_Meta_PP PF01053.20 CDO74915.1 - 2.3e-127 424.7 0.0 5e-127 423.6 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 CDO74915.1 - 9.5e-17 61.0 2.5 1.1e-16 60.8 0.0 2.6 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CDO74915.1 - 2e-05 24.9 0.4 7.7e-05 23.0 0.1 2.1 1 1 1 2 2 2 1 GHMP kinases C terminal Aminotran_1_2 PF00155.21 CDO74915.1 - 0.0017 17.6 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GalKase_gal_bdg PF10509.9 CDO74915.1 - 0.0027 17.2 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Met_gamma_lyase PF06838.11 CDO74915.1 - 0.0073 14.9 0.0 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 CDO74915.1 - 0.054 12.8 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family HATPase_c PF02518.26 CDO74916.1 - 7.3e-17 61.9 0.0 1.8e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CDO74916.1 - 7.8e-16 58.2 0.0 1.4e-14 54.2 0.0 2.7 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 CDO74916.1 - 3.3e-14 52.7 0.1 1.3e-13 50.7 0.1 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 CDO74916.1 - 2.1e-09 38.1 0.0 9.2e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 GAF domain Abhydrolase_1 PF00561.20 CDO74917.1 - 7.2e-22 78.3 0.3 1.4e-16 60.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO74917.1 - 2.8e-16 60.8 7.4 1.4e-15 58.5 7.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family WYL PF13280.6 CDO74917.1 - 2.7e-05 24.3 0.0 8.1e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 WYL domain Hydrolase_4 PF12146.8 CDO74917.1 - 6.1e-05 22.4 0.0 0.037 13.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 EHN PF06441.12 CDO74917.1 - 0.089 13.2 0.4 0.63 10.4 0.0 2.2 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CDO74918.1 - 2.2e-23 83.2 0.3 2.2e-18 66.9 0.2 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO74918.1 - 1.3e-16 61.9 0.5 1.8e-16 61.4 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO74918.1 - 1.2e-06 28.0 0.1 0.0003 20.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 CDO74918.1 - 0.0052 15.5 0.0 0.0075 15.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 CDO74918.1 - 0.04 14.0 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein EHN PF06441.12 CDO74918.1 - 0.051 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CDO74919.1 - 1.2e-21 77.6 0.3 1.6e-21 77.1 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO74919.1 - 6e-12 46.6 0.6 6.9e-12 46.4 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO74919.1 - 1e-05 24.9 0.0 1.2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 CDO74919.1 - 5.5e-05 22.0 0.0 6.6e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family AXE1 PF05448.12 CDO74919.1 - 0.022 13.5 0.0 0.032 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) EHN PF06441.12 CDO74919.1 - 0.12 12.8 0.1 0.4 11.1 0.0 1.9 2 0 0 2 2 2 0 Epoxide hydrolase N terminus adh_short PF00106.25 CDO74920.1 - 3.9e-40 137.4 3.0 5.5e-40 136.9 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO74920.1 - 1.5e-24 86.8 0.6 2.4e-24 86.2 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO74920.1 - 1.1e-05 25.4 0.6 1.6e-05 24.9 0.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CDO74920.1 - 0.038 13.9 0.3 0.078 12.9 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Retrotran_gag_2 PF14223.6 CDO74922.1 - 5.4e-17 61.7 0.0 1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CDO74922.1 - 8.8e-08 31.6 0.3 2e-07 30.5 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) CPSF100_C PF13299.6 CDO74922.1 - 0.57 10.3 6.1 0.13 12.4 2.0 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal XRN_N PF03159.18 CDO74922.1 - 0.74 9.2 4.2 1.2 8.5 2.2 2.0 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Spt20 PF12090.8 CDO74922.1 - 2 8.0 7.6 3.1 7.3 7.6 1.2 1 0 0 1 1 1 0 Spt20 family F-box-like PF12937.7 CDO74926.1 - 0.0072 16.2 0.1 0.025 14.5 0.1 2.0 1 0 0 1 1 1 1 F-box-like AChE_tetra PF08674.10 CDO74926.1 - 8 6.3 6.6 1.8 8.3 1.7 2.0 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain Transposase_21 PF02992.14 CDO74927.1 - 8.7e-09 34.9 0.0 1.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 CDO74927.1 - 0.11 11.9 0.0 5.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1258) zf-RVT PF13966.6 CDO74929.1 - 0.00013 22.6 0.0 0.00019 22.1 0.0 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase MFS_1 PF07690.16 CDO74930.1 - 5.2e-31 107.9 29.9 5.2e-31 107.9 29.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO74930.1 - 0.00041 18.9 1.5 0.00079 18.0 1.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) tRNA-synt_2c PF01411.19 CDO74931.1 - 6.2e-222 738.0 0.0 8.1e-222 737.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CDO74931.1 - 2.9e-17 62.5 0.5 2e-16 59.8 0.2 2.5 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CDO74931.1 - 5.3e-12 46.3 6.5 1.2e-11 45.2 6.5 1.7 1 0 0 1 1 1 1 DHHA1 domain PEHE PF15275.6 CDO74933.1 - 0.16 12.6 1.3 0.39 11.4 1.3 1.7 1 0 0 1 1 1 0 PEHE domain zf-RING_5 PF14634.6 CDO74934.1 - 0.046 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Aldo_ket_red PF00248.21 CDO74935.1 - 2.7e-36 125.3 0.0 2.3e-34 119.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family 7TMR-DISMED2 PF07696.11 CDO74935.1 - 0.19 11.8 0.0 4.2 7.4 0.0 2.2 1 1 0 2 2 2 0 7TMR-DISM extracellular 2 adh_short_C2 PF13561.6 CDO74936.1 - 1.3e-35 123.1 0.0 1.5e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO74936.1 - 4.8e-35 120.8 0.0 6.6e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO74936.1 - 1.3e-05 25.2 0.1 2.3e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 KR domain Terpene_synth_C PF03936.16 CDO74937.1 - 3.1e-09 36.6 0.0 4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 CDO74937.1 - 0.00099 18.1 0.0 0.0013 17.7 0.0 1.3 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) Ank_4 PF13637.6 CDO74938.1 - 1.3e-36 124.5 0.1 2e-14 53.7 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDO74938.1 - 3e-36 123.8 0.0 3.3e-11 43.6 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CDO74938.1 - 9e-35 117.6 0.2 2.5e-08 34.0 0.0 5.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 CDO74938.1 - 1.7e-34 117.4 0.8 1.1e-14 54.2 0.0 4.5 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDO74938.1 - 3.4e-33 109.9 0.0 1.5e-08 34.2 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Acyl-CoA_dh_2 PF08028.11 CDO74938.1 - 0.083 13.2 0.2 0.19 12.0 0.2 1.6 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Tfb2 PF03849.14 CDO74939.1 - 2.4e-50 171.5 0.1 3.1e-50 171.1 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CDO74939.1 - 3.3e-26 91.5 0.1 1.5e-25 89.4 0.3 1.9 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CDO74939.1 - 0.00064 19.9 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Gti1_Pac2 PF09729.9 CDO74940.1 - 9.4e-46 156.2 2.9 8.1e-37 127.1 0.2 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Terpene_synth_C PF03936.16 CDO74941.1 - 7.2e-07 28.8 0.0 1.3e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 CDO74941.1 - 0.11 12.6 0.1 0.59 10.2 0.0 2.2 3 0 0 3 3 3 0 Sporulation initiation phospho-transferase B, C-terminal DUF410 PF04190.13 CDO74942.1 - 3e-55 187.8 0.0 1.2e-54 185.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF410) Arv1 PF04161.13 CDO74943.1 - 6.2e-19 69.0 0.7 1e-17 65.0 0.7 2.3 1 1 0 1 1 1 1 Arv1-like family Steroid_dh PF02544.16 CDO74944.1 - 2.7e-36 124.8 4.5 4e-36 124.2 4.5 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 CDO74944.1 - 1.7e-06 27.6 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 CDO74944.1 - 0.0023 18.6 0.0 0.004 17.8 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF1295 PF06966.12 CDO74944.1 - 0.023 14.2 1.7 0.035 13.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Rad60-SLD PF11976.8 CDO74944.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MIP PF00230.20 CDO74945.1 - 5.7e-40 137.4 7.4 7.6e-40 137.0 7.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Tannase PF07519.11 CDO74946.1 - 6.1e-103 345.2 1.5 7.7e-103 344.9 1.5 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 CDO74946.1 - 0.16 11.2 0.0 0.36 10.1 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDO74947.1 - 1.4e-17 64.3 0.1 1.2e-13 51.3 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO74947.1 - 2.2e-17 64.4 0.2 3.1e-17 63.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO74947.1 - 3e-10 39.8 0.0 4.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CDO74947.1 - 1.8e-07 31.6 0.0 2.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 CDO74947.1 - 1.5e-06 28.1 0.1 3.9e-05 23.5 0.0 2.2 1 1 1 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 CDO74947.1 - 0.00055 19.5 0.0 0.00087 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 CDO74947.1 - 0.01 14.8 0.1 0.02 13.8 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 CDO74947.1 - 0.031 14.1 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2048 PF09752.9 CDO74947.1 - 0.073 12.2 0.0 8.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Palm_thioest PF02089.15 CDO74947.1 - 0.076 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Chlorophyllase PF07224.11 CDO74947.1 - 0.081 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.20 CDO74947.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Lipase_2 PF01674.18 CDO74947.1 - 0.22 11.0 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Cupin_1 PF00190.22 CDO74951.1 - 1.7e-38 131.6 0.3 1.7e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CDO74951.1 - 2.8e-24 84.6 0.8 6.4e-12 45.0 0.3 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 CDO74951.1 - 2.5e-09 36.7 0.1 0.00094 18.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 CDO74951.1 - 2.4e-06 27.5 0.0 0.00041 20.3 0.0 2.1 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase 3-HAO PF06052.12 CDO74951.1 - 0.00014 21.5 0.0 0.00058 19.5 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase ARD PF03079.14 CDO74951.1 - 0.0011 19.2 0.1 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 ARD/ARD' family AraC_binding PF02311.19 CDO74951.1 - 0.0041 17.0 0.3 0.039 13.8 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain UCH PF00443.29 CDO74952.1 - 1.2e-47 162.6 0.1 1.5e-47 162.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CDO74952.1 - 4.3e-20 72.5 1.5 2.9e-19 69.8 1.5 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_2 PF13240.6 CDO74952.1 - 0.01 15.5 8.7 0.39 10.5 0.3 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CDO74952.1 - 0.22 11.7 4.6 10 6.3 0.1 3.3 3 0 0 3 3 3 0 Zinc ribbon domain zf_UBZ PF18439.1 CDO74952.1 - 0.44 10.2 5.9 5.4 6.7 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger SDA1 PF05285.12 CDO74953.1 - 0.026 13.9 3.8 0.03 13.8 3.8 1.1 1 0 0 1 1 1 0 SDA1 Thg1C PF14413.6 CDO74954.1 - 3.3e-46 156.4 0.0 4.8e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 CDO74954.1 - 2.4e-31 108.4 0.1 3.3e-31 107.9 0.1 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Pterin_4a PF01329.19 CDO74956.1 - 1.6e-05 25.0 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Forkhead PF00250.18 CDO74957.1 - 1.4e-22 79.8 0.1 2.6e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain DUF4820 PF16091.5 CDO74957.1 - 0.46 9.8 2.9 0.15 11.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) GGACT PF06094.12 CDO74958.1 - 0.00067 20.3 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like tRNA-synt_1g PF09334.11 CDO74959.1 - 1.2e-104 350.2 1.4 3.6e-104 348.6 1.4 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 CDO74959.1 - 4.7e-08 33.1 7.0 1.1e-07 31.8 7.0 1.7 1 0 0 1 1 1 1 WHEP-TRS domain Anticodon_1 PF08264.13 CDO74959.1 - 3.1e-06 27.2 0.0 6.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Nsp1_C PF05064.13 CDO74959.1 - 0.024 14.5 1.2 0.048 13.5 1.2 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region DUF3323 PF11796.8 CDO74959.1 - 0.16 11.9 5.1 0.31 10.9 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Peptidase_C14 PF00656.22 CDO74960.1 - 4.8e-62 210.1 0.0 6e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 CDO74960.1 - 0.15 12.0 0.5 0.54 10.2 0.0 2.1 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Sugar_tr PF00083.24 CDO74961.1 - 8e-114 381.0 16.4 1.2e-113 380.4 16.4 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO74961.1 - 2.3e-28 99.2 51.5 8e-21 74.3 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UvrD-helicase PF00580.21 CDO74962.1 - 7.8e-63 212.9 0.0 1.3e-62 212.1 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CDO74962.1 - 9.3e-52 176.5 0.0 1.4e-50 172.7 0.0 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CDO74962.1 - 3.1e-31 108.7 0.0 8e-31 107.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CDO74962.1 - 9.9e-13 47.7 0.0 2.8e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CDO74962.1 - 5e-08 33.0 0.5 0.04 13.6 0.0 3.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 CDO74962.1 - 8.3e-06 25.6 0.0 0.00031 20.4 0.0 3.1 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 CDO74962.1 - 1.8e-05 24.5 0.0 0.039 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CDO74962.1 - 0.0047 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain PMP22_Claudin PF00822.20 CDO74962.1 - 0.0088 15.9 0.4 0.018 14.9 0.4 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Membralin PF09746.9 CDO74962.1 - 0.064 12.3 0.4 0.11 11.5 0.2 1.4 2 0 0 2 2 2 0 Tumour-associated protein HSP20 PF00011.21 CDO74963.1 - 3.5e-10 39.9 0.0 5.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Asp PF00026.23 CDO74964.1 - 2.9e-54 184.6 0.0 3.8e-52 177.7 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO74964.1 - 1.6e-12 48.1 1.9 3.2e-07 30.7 0.2 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO74964.1 - 0.021 15.5 0.6 1.1 9.9 0.1 3.2 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 CDO74964.1 - 0.046 14.3 0.1 2.7 8.6 0.0 3.0 2 2 0 2 2 2 0 gag-polyprotein putative aspartyl protease Metallophos PF00149.28 CDO74965.1 - 2.2e-08 34.8 0.0 7.9e-08 33.0 0.0 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDO74965.1 - 0.006 16.8 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SDA1 PF05285.12 CDO74965.1 - 0.33 10.3 5.0 0.54 9.6 5.0 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 CDO74965.1 - 0.58 8.2 6.1 1.1 7.3 6.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CDO74965.1 - 0.87 7.8 4.3 1.5 7.0 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 CDO74965.1 - 2.6 8.5 12.7 2.2 8.7 6.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 CDO74965.1 - 5.1 6.8 7.3 0.49 10.0 1.4 2.0 2 0 0 2 2 2 0 FAM176 family Cupin_1 PF00190.22 CDO74966.1 - 5.9e-43 146.1 0.0 8.1e-21 74.2 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CDO74966.1 - 6.9e-27 93.0 0.1 5.4e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 Cupin domain MannoseP_isomer PF01050.18 CDO74966.1 - 1.8e-07 31.2 0.0 9.3e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.12 CDO74966.1 - 2.1e-07 30.5 0.0 0.011 15.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 CDO74966.1 - 5.4e-06 26.4 0.1 0.00029 20.7 0.0 2.5 2 0 0 2 2 2 1 AraC-like ligand binding domain 3-HAO PF06052.12 CDO74966.1 - 0.0028 17.3 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Ectoine_synth PF06339.12 CDO74966.1 - 0.0056 16.9 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 1 Ectoine synthase Pirin_C PF05726.13 CDO74966.1 - 0.01 16.2 0.0 0.39 11.1 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain SET PF00856.28 CDO74967.1 - 0.003 18.0 0.0 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 SET domain PET PF06297.14 CDO74967.1 - 0.24 11.7 0.8 0.44 10.9 0.1 1.8 2 0 0 2 2 2 0 PET Domain Transketolase_N PF00456.21 CDO74968.1 - 5.4e-15 55.2 1.7 4.8e-14 52.0 1.6 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 CDO74968.1 - 3.3e-09 36.7 0.0 6.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 CDO74968.1 - 1.1e-05 25.2 0.5 2.3e-05 24.2 0.2 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 CDO74968.1 - 6.2e-05 22.8 0.1 0.00027 20.7 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 CDO74968.1 - 0.00059 18.9 0.0 0.00092 18.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component ADH_N PF08240.12 CDO74969.1 - 1.5e-23 82.8 2.2 2.4e-23 82.1 2.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO74969.1 - 9.2e-18 64.5 0.0 1.6e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO74969.1 - 8.7e-07 30.1 0.0 1.4e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CDO74969.1 - 0.00023 20.7 0.1 0.00044 19.8 0.1 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CDO74969.1 - 0.0067 15.7 0.2 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IBD PF10416.9 CDO74969.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD NAD_binding_10 PF13460.6 CDO74969.1 - 0.033 14.1 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding ELFV_dehydrog PF00208.21 CDO74969.1 - 0.088 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HgmA PF04209.13 CDO74970.1 - 2.7e-138 461.2 0.0 1.2e-127 426.2 0.0 2.0 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase F-box-like PF12937.7 CDO74971.1 - 1.7e-05 24.6 2.6 5.2e-05 23.1 2.6 1.9 1 0 0 1 1 1 1 F-box-like FRG PF08867.11 CDO74971.1 - 0.025 15.5 0.1 0.043 14.8 0.1 1.3 1 0 0 1 1 1 0 FRG domain Aminotran_5 PF00266.19 CDO74972.1 - 2.2e-15 56.5 0.0 5e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 CDO74972.1 - 0.037 13.2 0.0 6.9 5.7 0.0 2.8 3 0 0 3 3 3 0 Aminotransferase class I and II PRK PF00485.18 CDO74973.1 - 2.3e-52 177.6 0.0 3.3e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 CDO74973.1 - 1.6e-44 151.9 0.0 1.2e-41 142.4 0.0 3.1 2 1 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.6 CDO74973.1 - 0.00015 22.3 0.0 0.00036 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDO74973.1 - 0.00053 20.2 0.0 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CDO74973.1 - 0.0046 16.3 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin CoaE PF01121.20 CDO74973.1 - 0.045 13.4 0.9 0.61 9.7 0.3 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase CTU2 PF10288.9 CDO74974.1 - 1.3e-17 64.0 0.2 6.1e-17 61.9 0.0 2.2 3 0 0 3 3 3 1 Cytoplasmic tRNA 2-thiolation protein 2 zf-C3HC4_3 PF13920.6 CDO74974.1 - 5.3 7.0 12.5 0.42 10.5 3.3 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Na_Ca_ex PF01699.24 CDO74975.1 - 2.9e-23 82.5 23.6 3.9e-17 62.6 9.4 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF3810 PF12725.7 CDO74975.1 - 0.012 15.0 1.4 0.022 14.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) ATG27 PF09451.10 CDO74975.1 - 0.21 11.4 0.0 8.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Autophagy-related protein 27 Peptidase_M48 PF01435.18 CDO74977.1 - 2.5e-19 69.9 0.0 4.8e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Svf1_C PF17187.4 CDO74978.1 - 9.8e-49 165.4 0.0 1.9e-48 164.4 0.0 1.5 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 CDO74978.1 - 1.3e-47 161.9 0.0 1.7e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain WTF PF03303.13 CDO74979.1 - 2.8 7.6 6.1 0.35 10.6 1.1 1.9 2 0 0 2 2 2 0 WTF protein MFS_1 PF07690.16 CDO74981.1 - 4.3e-21 75.2 44.0 4.3e-21 75.2 44.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO74981.1 - 3.2e-14 52.3 12.9 4.4e-10 38.6 4.5 2.6 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CDO74981.1 - 0.00018 20.5 7.6 0.00018 20.5 7.6 3.1 2 2 0 2 2 2 1 Sugar (and other) transporter Pkinase PF00069.25 CDO74982.1 - 6.1e-27 94.6 0.0 7.8e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO74982.1 - 1.8e-12 47.1 0.0 2.5e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO74982.1 - 2.8e-08 33.0 0.0 4.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO74982.1 - 0.0015 18.5 0.0 0.45 10.4 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family DSBA PF01323.20 CDO74983.1 - 2.6e-29 102.4 0.1 3.6e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 CDO74983.1 - 1.1e-05 25.6 0.2 0.00017 21.8 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 CDO74983.1 - 0.0025 17.8 0.3 0.043 13.9 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain AvrRpt-cleavage PF05627.11 CDO74983.1 - 0.032 13.6 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr WASH-7_N PF14745.6 CDO74983.1 - 0.075 11.5 0.0 0.096 11.2 0.0 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal Frag1 PF10277.9 CDO74984.1 - 2.2e-31 109.1 10.6 2.7e-31 108.8 10.6 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family NMN_transporter PF04973.12 CDO74984.1 - 0.023 14.7 5.1 0.45 10.5 0.1 2.1 1 1 1 2 2 2 0 Nicotinamide mononucleotide transporter PAP2_3 PF14378.6 CDO74984.1 - 0.06 13.0 5.8 0.11 12.2 0.3 2.2 1 1 1 2 2 2 0 PAP2 superfamily Bax1-I PF01027.20 CDO74984.1 - 0.063 13.1 13.6 0.14 12.0 13.6 1.4 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 CDO74984.1 - 0.11 10.7 9.5 0.15 10.3 9.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cation_ATPase_C PF00689.21 CDO74984.1 - 0.14 11.9 6.5 0.21 11.3 6.5 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus TssN PF17555.2 CDO74984.1 - 0.17 11.2 7.9 0.31 10.4 7.9 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN 7TM_GPCR_Srh PF10318.9 CDO74984.1 - 0.27 10.2 6.3 0.18 10.8 4.9 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh DHHC PF01529.20 CDO74984.1 - 3.4 7.8 10.1 5.1 7.2 0.2 2.4 2 1 0 2 2 2 0 DHHC palmitoyltransferase 7TMR-DISM_7TM PF07695.11 CDO74984.1 - 5.3 6.9 17.3 50 3.7 16.9 2.1 1 1 0 1 1 1 0 7TM diverse intracellular signalling NTP_transf_9 PF04248.12 CDO74985.1 - 1.4e-37 127.4 0.6 5.3e-30 103.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF427) DUF1080 PF06439.11 CDO74985.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) HEAT_2 PF13646.6 CDO74987.1 - 0.0056 17.1 2.0 0.021 15.2 0.2 2.7 2 0 0 2 2 2 1 HEAT repeats TPR_14 PF13428.6 CDO74987.1 - 3.1 8.9 14.1 1.6 9.8 0.1 4.9 3 2 2 5 5 5 0 Tetratricopeptide repeat Ribosomal_L10 PF00466.20 CDO74988.1 - 9.2e-25 86.7 0.6 2.2e-24 85.5 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 CDO74988.1 - 2.9e-23 81.6 0.3 5.7e-23 80.7 0.1 1.6 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CDO74988.1 - 9.6e-21 74.2 13.2 9.9e-21 74.1 9.6 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Methyltransf_23 PF13489.6 CDO74989.1 - 0.00059 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO74989.1 - 0.041 14.6 0.1 0.43 11.3 0.1 2.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CDO74989.1 - 0.06 14.1 0.4 4.2 8.1 0.2 2.9 2 1 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 CDO74989.1 - 0.075 12.6 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW p450 PF00067.22 CDO74990.1 - 7.4e-68 229.4 0.0 8.9e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNB PF00773.19 CDO74991.1 - 5.4e-50 170.6 0.0 8.5e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 RNB domain Pkinase PF00069.25 CDO74993.1 - 3.7e-44 151.1 0.0 5e-25 88.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO74993.1 - 6.6e-22 78.0 0.0 7e-21 74.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO74993.1 - 2.5e-06 27.0 0.0 0.0088 15.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CDO74993.1 - 0.00014 21.9 0.2 0.002 18.1 0.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO74993.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-C3HC PF07967.13 CDO74994.1 - 7.7e-26 90.7 0.0 9.6e-25 87.1 0.0 2.3 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.10 CDO74994.1 - 1.9e-14 53.5 0.8 5.5e-10 39.3 0.0 3.2 3 0 0 3 3 3 2 Rsm1-like DM PF00751.18 CDO74994.1 - 0.13 12.1 0.4 6.3 6.8 0.2 2.6 2 0 0 2 2 2 0 DM DNA binding domain DUF2370 PF10176.9 CDO74995.1 - 9e-63 211.9 0.0 1.5e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Glyco_transf_20 PF00982.21 CDO74996.1 - 1.1e-188 627.8 0.0 8.1e-188 624.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 CDO74996.1 - 0.00054 20.4 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 CDO74996.1 - 0.055 13.0 0.2 2.8 7.5 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferases group 1 PP2C PF00481.21 CDO74997.1 - 0.019 14.6 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C DNA_pol3_delta2 PF13177.6 CDO74998.1 - 4.4e-12 46.1 0.0 8.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CDO74998.1 - 5.9e-06 26.7 0.6 1.6e-05 25.3 0.6 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 CDO74998.1 - 0.00011 22.1 0.2 0.00018 21.3 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 CDO74998.1 - 0.0096 16.3 0.4 0.079 13.3 0.1 2.4 2 2 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 CDO74998.1 - 0.0098 15.8 0.0 0.034 14.1 0.0 2.0 2 1 0 2 2 2 1 Rad17 P-loop domain TSC21 PF15217.6 CDO74998.1 - 0.052 13.5 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 TSC21 family DUF3802 PF12290.8 CDO74998.1 - 0.057 13.9 1.0 0.13 12.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) AAA_22 PF13401.6 CDO74998.1 - 0.08 13.2 1.6 1 9.6 0.9 2.7 2 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 CDO74998.1 - 0.083 12.7 2.2 0.89 9.4 0.6 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_5 PF07728.14 CDO74998.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RT_RNaseH_2 PF17919.1 CDO74999.1 - 6.8e-12 45.3 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO74999.1 - 9.9e-08 32.2 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDO74999.1 - 0.00075 20.0 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO74999.1 - 0.0053 17.4 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CDO74999.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease APP_E2 PF12925.7 CDO75000.1 - 0.086 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein Abhydrolase_6 PF12697.7 CDO75001.1 - 1.8e-15 58.2 1.1 2.1e-15 57.9 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDO75001.1 - 1.3e-14 54.5 0.1 2.3e-12 47.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO75001.1 - 4.6e-11 42.5 0.1 2.5e-09 36.8 0.1 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 CDO75001.1 - 0.01 16.0 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 CDO75001.1 - 0.012 15.4 0.0 0.069 12.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.16 CDO75002.1 - 2.7e-28 98.9 45.8 2.3e-26 92.6 39.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CDO75002.1 - 0.00015 21.2 27.0 0.0025 17.2 27.0 2.1 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Pam17 PF08566.10 CDO75002.1 - 0.086 12.7 0.2 0.27 11.0 0.2 1.9 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 DUF2034 PF10356.9 CDO75003.1 - 2.4e-17 63.0 0.6 5.9e-16 58.4 0.6 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 CDO75003.1 - 0.00016 21.6 0.0 0.0024 17.9 0.0 2.5 2 1 0 2 2 2 1 Restriction endonuclease RdRP PF05183.12 CDO75004.1 - 2.3e-102 343.6 0.0 3.4e-102 343.0 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase TORC_M PF12885.7 CDO75004.1 - 0.92 9.4 3.7 1.8 8.5 3.7 1.4 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Mob1_phocein PF03637.17 CDO75005.1 - 1.5e-26 93.5 0.1 2.4e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Transp_cyt_pur PF02133.15 CDO75006.1 - 9.1e-33 113.7 30.1 8.7e-32 110.4 30.1 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4017 PF13209.6 CDO75007.1 - 0.01 15.7 0.5 0.016 15.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) Kinetochor_Ybp2 PF08568.10 CDO75008.1 - 3.4e-14 52.3 0.0 3.9e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family, YAP/Alf4/glomulin WD40 PF00400.32 CDO75008.1 - 1.6e-12 47.7 4.6 7.4e-05 23.4 0.6 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75008.1 - 9.5e-05 22.6 0.0 0.0031 17.8 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L7Ae PF01248.26 CDO75009.1 - 1.7e-27 95.0 2.8 2e-27 94.7 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 CDO75009.1 - 0.19 12.0 1.0 2.5 8.4 0.2 2.2 1 1 1 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding ABC_membrane_2 PF06472.15 CDO75010.1 - 1.3e-53 182.2 3.2 2.6e-35 122.1 0.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CDO75010.1 - 2.5e-16 60.4 0.0 5.3e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 CDO75010.1 - 0.029 14.3 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 CDO75010.1 - 0.033 14.6 0.0 0.091 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 CDO75010.1 - 0.14 11.6 0.0 0.86 9.0 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDO75010.1 - 0.17 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CDO75010.1 - 0.19 11.5 1.7 0.39 10.4 1.7 1.6 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.8 CDO75010.1 - 0.38 8.2 1.2 0.44 8.0 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Acetyltransf_8 PF13523.6 CDO75011.1 - 2e-35 121.6 0.2 1.5e-34 118.8 0.7 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.26 CDO75013.1 - 1e-26 93.5 0.0 3.3e-26 91.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO75013.1 - 2.9e-19 70.4 0.0 5.1e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 CDO75013.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain PA PF02225.22 CDO75013.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.9 1 1 0 1 1 1 0 PA domain adh_short PF00106.25 CDO75013.1 - 0.11 11.9 0.5 0.24 10.8 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase DUF2855 PF11017.8 CDO75013.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) DUF4121 PF13497.6 CDO75013.1 - 0.2 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) FA_desaturase PF00487.24 CDO75015.1 - 6.2e-06 26.2 0.7 6.9e-06 26.1 0.7 1.1 1 0 0 1 1 1 1 Fatty acid desaturase XPG_I PF00867.18 CDO75016.1 - 7.3e-18 64.7 0.0 1.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDO75016.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 XPG N-terminal domain Yip1 PF04893.17 CDO75018.1 - 0.0069 16.1 1.8 0.014 15.2 1.8 1.4 1 0 0 1 1 1 1 Yip1 domain DUF3592 PF12158.8 CDO75018.1 - 0.11 12.5 0.0 0.81 9.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3592) WW PF00397.26 CDO75018.1 - 0.15 12.2 0.2 0.36 11.0 0.2 1.7 1 0 0 1 1 1 0 WW domain DUF4231 PF14015.6 CDO75018.1 - 0.35 11.3 4.3 0.12 12.9 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Coatomer_WDAD PF04053.14 CDO75019.1 - 3.6e-153 510.8 0.0 5.2e-153 510.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CDO75019.1 - 1.6e-40 136.3 1.2 1.3e-07 32.2 0.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75019.1 - 4.3e-08 33.3 0.0 0.098 13.0 0.0 6.5 3 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CDO75019.1 - 0.00033 20.7 0.1 12 6.0 0.0 5.0 5 1 1 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 CDO75019.1 - 0.0021 16.8 0.2 0.056 12.1 0.0 2.9 2 1 1 3 3 3 1 Nucleoporin Nup120/160 eIF2A PF08662.11 CDO75019.1 - 0.012 15.5 0.2 49 3.7 0.0 4.3 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 CDO75019.1 - 0.072 12.7 1.3 0.75 9.3 0.2 2.9 3 0 0 3 3 3 0 PQQ-like domain Chitin_synth_2 PF03142.15 CDO75020.1 - 4.6e-233 774.6 0.1 6e-233 774.2 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CDO75020.1 - 4.3e-100 335.9 0.0 4.6e-74 249.9 0.0 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.28 CDO75020.1 - 2.6e-19 69.1 0.1 1.1e-13 51.2 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 CDO75020.1 - 2.6e-17 62.5 0.1 7e-17 61.1 0.1 1.8 1 0 0 1 1 1 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 CDO75020.1 - 9.5e-15 55.1 0.0 4.5e-13 49.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CDO75020.1 - 8.6e-14 51.9 5.2 2.3e-13 50.5 5.2 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CDO75020.1 - 1.9e-08 34.3 0.0 0.0001 22.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CDO75020.1 - 0.00096 18.7 0.0 0.042 13.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF1275 PF06912.11 CDO75022.1 - 0.12 12.3 0.7 3.6 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) WD40 PF00400.32 CDO75023.1 - 2e-33 113.9 19.9 1.6e-06 28.7 1.1 8.9 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75023.1 - 2.3e-16 59.9 0.5 0.00082 19.6 0.1 6.3 2 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO75023.1 - 8e-05 21.7 2.6 16 4.3 0.1 5.6 3 1 3 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 CDO75023.1 - 0.00015 21.4 7.7 0.031 13.9 0.3 3.3 2 1 1 3 3 3 3 PQQ-like domain DUF5440 PF17509.2 CDO75023.1 - 0.13 11.9 0.0 0.37 10.4 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5440) PQQ_3 PF13570.6 CDO75023.1 - 0.24 11.9 7.1 5.6 7.6 0.0 5.3 5 2 0 5 5 5 0 PQQ-like domain NACHT PF05729.12 CDO75024.1 - 2.6e-08 34.0 0.0 1.3e-07 31.7 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CDO75024.1 - 1.5e-07 32.0 1.3 1.6e-06 28.6 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CDO75024.1 - 1.2e-06 28.8 0.1 9.9e-05 22.6 0.0 3.2 3 1 1 4 4 4 1 AAA domain AAA PF00004.29 CDO75024.1 - 4.2e-06 27.2 0.0 0.0028 18.1 0.0 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 CDO75024.1 - 0.00048 19.3 0.0 0.00078 18.6 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 CDO75024.1 - 0.0034 17.1 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CDO75024.1 - 0.042 13.0 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 CDO75024.1 - 0.046 13.6 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF1678 PF07913.11 CDO75024.1 - 0.079 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) ABC_tran PF00005.27 CDO75024.1 - 0.09 13.3 0.1 0.43 11.1 0.0 2.1 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 CDO75024.1 - 0.093 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 CDO75024.1 - 0.12 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 CDO75024.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CDO75024.1 - 0.16 11.5 0.6 0.64 9.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CDO75024.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 NTPase KAP_NTPase PF07693.14 CDO75024.1 - 1.4 8.0 4.5 8.6 5.5 0.1 2.9 2 1 0 3 3 3 0 KAP family P-loop domain TMEM171 PF15471.6 CDO75025.1 - 0.012 14.6 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 CAP_N PF01213.19 CDO75025.1 - 0.088 12.3 0.6 0.1 12.1 0.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Sde2_N_Ubi PF13019.6 CDO75025.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain RVT_2 PF07727.14 CDO75026.1 - 1.1e-72 244.6 0.0 1.4e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrophobin PF01185.18 CDO75028.1 - 4.2e-24 85.0 10.3 5e-24 84.7 10.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Cnn_1N PF07989.11 CDO75029.1 - 3.2e-24 84.9 26.7 1.1e-23 83.2 10.4 13.0 7 2 5 12 12 12 4 Centrosomin N-terminal motif 1 Fez1 PF06818.15 CDO75029.1 - 0.00039 20.9 28.4 0.00039 20.9 28.4 8.0 1 1 4 5 5 5 2 Fez1 DHR10 PF18595.1 CDO75029.1 - 0.0027 17.7 19.2 0.0027 17.7 19.2 12.6 4 3 7 11 11 11 6 Designed helical repeat protein 10 domain HrpB7 PF09486.10 CDO75029.1 - 0.0076 16.6 12.0 0.0076 16.6 12.0 10.4 3 2 6 10 10 10 3 Bacterial type III secretion protein (HrpB7) HIP1_clath_bdg PF16515.5 CDO75029.1 - 0.022 15.4 0.3 0.022 15.4 0.3 12.9 5 3 7 12 12 12 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4479 PF14794.6 CDO75029.1 - 0.24 11.3 7.0 7.6 6.5 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4479) DUF1664 PF07889.12 CDO75029.1 - 8.5 6.4 83.8 0.23 11.5 4.1 10.7 4 3 8 12 12 12 0 Protein of unknown function (DUF1664) adh_short_C2 PF13561.6 CDO75030.1 - 1.3e-33 116.5 0.0 1.6e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO75030.1 - 6.5e-31 107.3 0.0 8e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase C2 PF00168.30 CDO75031.1 - 8.5e-15 54.9 0.1 1.3e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 C2 domain Transferrin PF00405.17 CDO75031.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Transferrin DUF92 PF01940.16 CDO75033.1 - 6.5e-47 159.9 4.8 8e-47 159.6 4.8 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 p450 PF00067.22 CDO75034.1 - 4.5e-51 174.1 0.0 1.4e-50 172.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.22 CDO75035.1 - 0.0037 16.6 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 CDO75036.1 - 3.3e-37 127.9 0.0 6.8e-24 84.8 0.1 2.5 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO75036.1 - 0.001 18.4 0.1 0.0023 17.2 0.0 1.4 1 1 0 1 1 1 1 Subtilase family X PF00739.19 CDO75036.1 - 0.98 9.5 3.7 0.62 10.2 1.1 1.9 2 0 0 2 2 2 0 Trans-activation protein X Myb_DNA-bind_4 PF13837.6 CDO75037.1 - 1.3e-09 38.3 0.1 1.6e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CDO75037.1 - 2.8e-09 37.8 0.0 3.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO75037.1 - 0.00021 21.3 0.3 0.0007 19.6 0.3 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CDO75037.1 - 0.0021 18.2 0.3 0.0037 17.4 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDO75037.1 - 0.029 14.6 0.2 0.046 14.0 0.2 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain p450 PF00067.22 CDO75038.1 - 2.8e-52 178.0 0.0 1.9e-36 125.8 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Helitron_like_N PF14214.6 CDO75039.1 - 2e-50 171.7 0.0 2.3e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus p450 PF00067.22 CDO75040.1 - 2.2e-41 142.1 0.1 6.1e-41 140.6 0.1 1.5 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 CDO75041.1 - 1.1e-37 129.8 0.0 1.5e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75041.1 - 3.7e-13 49.3 0.0 6.6e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO75041.1 - 0.0019 17.6 0.0 0.007 15.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Retrotrans_gag PF03732.17 CDO75043.1 - 4.3e-05 23.7 0.6 8.9e-05 22.7 0.6 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO75044.1 - 1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 CDO75044.1 - 0.00046 20.4 0.6 0.0064 16.7 0.5 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein Apt1 PF10351.9 CDO75044.1 - 5.9 5.6 7.4 8.2 5.2 7.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.25 CDO75046.1 - 1.6e-06 27.7 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CDO75046.1 - 8.7e-06 24.8 0.0 1.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDO75046.1 - 9.6e-06 25.1 0.4 1.4e-05 24.6 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO75046.1 - 4.5e-05 23.5 0.1 6.7e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO75046.1 - 0.0013 18.4 0.1 0.0018 17.9 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CDO75046.1 - 0.006 16.2 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.20 CDO75046.1 - 0.023 14.0 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_Tyr PF07714.17 CDO75046.1 - 0.059 12.6 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Haspin_kinase PF12330.8 CDO75046.1 - 0.065 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CDO75046.1 - 0.15 11.5 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1802 PF08819.11 CDO75047.1 - 0.015 15.1 0.2 0.025 14.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) NapB PF03892.14 CDO75048.1 - 0.11 12.5 0.8 0.25 11.3 0.8 1.6 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) DUF5320 PF17253.2 CDO75048.1 - 0.17 13.0 6.0 0.093 13.8 3.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) TEX19 PF15553.6 CDO75048.1 - 0.87 9.5 6.1 11 6.0 1.6 2.3 1 1 1 2 2 2 0 Testis-expressed protein 19 CNOT11 PF10155.9 CDO75049.1 - 2.2e-17 63.4 0.0 3.8e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Pkinase PF00069.25 CDO75050.1 - 3.6e-77 259.3 0.4 4.2e-77 259.1 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75050.1 - 1.3e-54 185.3 0.3 1.7e-54 184.8 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO75050.1 - 3.5e-07 29.8 0.1 1.4e-06 27.9 0.1 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDO75050.1 - 1.3e-06 27.5 0.1 2e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CDO75050.1 - 2.6e-06 26.6 1.3 3.9e-06 26.1 1.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CDO75050.1 - 0.00011 22.3 0.2 0.0049 16.8 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CDO75050.1 - 0.0064 15.6 1.8 0.0071 15.4 0.3 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Kdo PF06293.14 CDO75050.1 - 0.087 12.2 0.2 0.19 11.1 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CM_1 PF07736.11 CDO75050.1 - 0.15 12.4 0.1 0.57 10.6 0.0 1.9 2 0 0 2 2 2 0 Chorismate mutase type I PBD PF00786.28 CDO75051.1 - 2e-23 82.5 0.0 4.5e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 CDO75051.1 - 7.4e-08 32.8 0.3 1.4e-07 32.0 0.3 1.4 1 0 0 1 1 1 1 PH domain DASH_Dam1 PF08653.10 CDO75052.1 - 9.7e-12 44.5 0.0 2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Dam1 Glyco_transf_20 PF00982.21 CDO75053.1 - 1.6e-149 498.6 0.0 2.3e-149 498.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CDO75053.1 - 5.6e-24 84.6 0.0 1.5e-22 79.9 0.0 2.2 2 0 0 2 2 2 1 Trehalose-phosphatase Peptidase_M28 PF04389.17 CDO75054.1 - 0.0031 17.2 0.0 0.0034 17.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M28 PF04389.17 CDO75055.1 - 1.5e-31 109.6 0.0 2.2e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CDO75055.1 - 7.3e-08 32.4 0.1 2.4e-07 30.7 0.1 1.9 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 CDO75055.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Nicastrin RVT_1 PF00078.27 CDO75057.1 - 1.4e-09 37.8 0.0 2.8e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO75057.1 - 9.6e-09 35.6 0.0 1.8e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.6 CDO75057.1 - 2.8e-05 23.9 0.0 6.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 CDO75057.1 - 0.0012 19.5 0.0 0.0032 18.2 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PAS_4 PF08448.10 CDO75058.1 - 0.065 13.5 0.3 1 9.6 0.0 2.3 2 0 0 2 2 2 0 PAS fold RVT_1 PF00078.27 CDO75059.1 - 4.5e-17 62.3 0.0 4.9e-15 55.6 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO75059.1 - 8.7e-07 29.2 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 CDO75059.1 - 0.094 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase-like ATP_bind_1 PF03029.17 CDO75060.1 - 1.7e-73 247.4 0.0 2.1e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CDO75060.1 - 0.14 12.3 0.2 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain GST_N_3 PF13417.6 CDO75061.1 - 8.5e-11 42.1 0.0 1.5e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO75061.1 - 5e-08 33.1 0.0 8.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO75061.1 - 1.8e-07 31.4 0.1 4.8e-07 30.0 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO75061.1 - 0.0002 21.3 0.2 0.00041 20.3 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DDE_3 PF13358.6 CDO75062.1 - 3.1e-12 46.4 0.8 4e-12 46.1 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Terminase_6C PF17289.2 CDO75062.1 - 0.21 11.7 0.0 0.27 11.3 0.0 1.1 1 0 0 1 1 1 0 Terminase RNaseH-like domain Abhydrolase_6 PF12697.7 CDO75064.1 - 8.2e-16 59.3 5.6 1e-15 59.0 5.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AIF_C PF14721.6 CDO75064.1 - 0.061 13.7 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MFS_1 PF07690.16 CDO75065.1 - 1.8e-38 132.4 54.0 1.8e-38 132.4 54.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO75065.1 - 1.7e-26 92.9 21.9 2.1e-26 92.5 21.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CDO75065.1 - 3e-13 49.4 11.5 3e-13 49.4 11.5 3.2 2 2 1 3 3 3 1 Sugar (and other) transporter DUF1700 PF08006.11 CDO75065.1 - 7.5 6.1 8.2 0.73 9.3 2.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) p450 PF00067.22 CDO75066.1 - 1.3e-54 185.7 0.0 1.9e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CDO75067.1 - 2.5e-62 211.2 0.0 1.9e-60 205.0 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 betaPIX_CC PF16523.5 CDO75072.1 - 0.23 11.3 2.7 0.26 11.1 1.6 1.6 2 0 0 2 2 2 0 betaPIX coiled coil SNARE_assoc PF09335.11 CDO75073.1 - 1.7e-18 67.3 7.6 1.7e-18 67.3 7.6 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1230 PF06799.11 CDO75073.1 - 0.074 13.2 0.2 0.18 11.9 0.2 1.6 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 MFS_1_like PF12832.7 CDO75073.1 - 2.4 6.9 9.0 4.6 6.0 9.0 1.4 1 0 0 1 1 1 0 MFS_1 like family DUF659 PF04937.15 CDO75074.1 - 1e-15 57.9 0.0 1.9e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CDO75074.1 - 0.0007 19.3 1.1 0.0015 18.3 1.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4148 PF13663.6 CDO75075.1 - 0.031 14.5 1.3 0.081 13.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Retrotran_gag_2 PF14223.6 CDO75077.1 - 1.2e-08 34.7 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Sad1_UNC PF07738.13 CDO75080.1 - 1.1e-18 67.6 0.0 5.5e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Transposase_21 PF02992.14 CDO75085.1 - 1e-18 67.4 0.0 1.9e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 CDO75085.1 - 0.00011 21.7 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) FPP PF05911.11 CDO75085.1 - 0.022 13.0 9.9 0.034 12.3 9.9 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Prefoldin PF02996.17 CDO75085.1 - 0.057 13.3 0.1 0.057 13.3 0.1 3.1 2 1 1 3 3 3 0 Prefoldin subunit EspB PF05802.11 CDO75085.1 - 0.089 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial EspB protein Prominin PF05478.11 CDO75085.1 - 0.21 9.5 2.4 0.39 8.6 2.4 1.3 1 0 0 1 1 1 0 Prominin Plavaka PF18759.1 CDO75085.1 - 0.23 10.7 0.0 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Plavaka transposase DUF4618 PF15397.6 CDO75085.1 - 0.25 10.7 12.2 0.56 9.6 12.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) BLOC1_2 PF10046.9 CDO75085.1 - 0.53 10.6 7.6 0.85 10.0 0.4 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 CDO75085.1 - 0.83 10.3 4.9 15 6.3 0.9 2.7 1 1 0 2 2 2 0 Initiation control protein YabA DUF1640 PF07798.11 CDO75085.1 - 0.86 9.6 6.7 1.5 8.8 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TarH PF02203.15 CDO75085.1 - 1.5 8.8 4.6 0.78 9.6 0.5 2.4 2 0 0 2 2 2 0 Tar ligand binding domain homologue DUF4407 PF14362.6 CDO75085.1 - 1.9 7.8 5.0 3.5 6.9 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DegS PF05384.11 CDO75085.1 - 3.4 7.2 10.4 0.13 11.7 1.6 2.3 1 1 1 2 2 2 0 Sensor protein DegS Dimer_Tnp_hAT PF05699.14 CDO75086.1 - 1.2e-22 79.5 0.0 2.4e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 CDO75086.1 - 4.5e-05 23.8 0.4 0.00015 22.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) DUF4218 PF13960.6 CDO75087.1 - 6.8e-08 32.1 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF4542 PF15075.6 CDO75087.1 - 0.034 14.5 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) WD40 PF00400.32 CDO75088.1 - 1.8e-17 63.4 13.4 1.5e-07 31.9 0.8 6.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase PF00069.25 CDO75088.1 - 1.9e-17 63.5 0.0 8.5e-17 61.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75088.1 - 1.8e-08 34.0 0.0 0.00037 19.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT PF02985.22 CDO75088.1 - 1.7e-07 30.9 12.6 0.52 10.7 0.1 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 CDO75088.1 - 0.00017 21.9 0.6 0.5 10.8 0.0 3.9 2 2 2 4 4 4 2 HEAT repeats Cnd1 PF12717.7 CDO75088.1 - 0.071 13.2 6.7 10 6.2 0.1 3.4 1 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 CDO75088.1 - 0.087 13.1 7.2 0.68 10.3 0.2 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Nucleoporin_N PF08801.11 CDO75088.1 - 0.18 10.5 0.7 72 1.9 0.0 3.6 2 2 2 4 4 4 0 Nup133 N terminal like UcrQ PF02939.16 CDO75090.1 - 3.5e-31 106.9 3.1 4.3e-31 106.7 3.1 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 CDO75090.1 - 3.1e-05 24.3 0.1 4.1e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 HSP20 PF00011.21 CDO75091.1 - 1.1e-10 41.5 0.0 2.3e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDO75091.1 - 5.1e-05 22.8 0.0 0.00011 21.7 0.0 1.5 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Phage_GPL PF05926.11 CDO75091.1 - 0.074 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Phage head completion protein (GPL) TPT PF03151.16 CDO75092.1 - 7e-34 117.5 8.6 1.6e-33 116.3 8.6 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CDO75092.1 - 6.1e-10 38.8 13.7 1.7e-09 37.3 13.7 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDO75092.1 - 6e-08 32.9 26.0 0.00012 22.3 9.3 2.9 3 0 0 3 3 3 2 EamA-like transporter family zf-RING_UBOX PF13445.6 CDO75093.1 - 3.1e-07 30.3 6.2 7.1e-07 29.2 6.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDO75093.1 - 4.7e-07 29.6 6.5 4.7e-07 29.6 6.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDO75093.1 - 1.4e-06 28.0 4.3 1.4e-06 28.0 4.3 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDO75093.1 - 1.7e-06 27.7 4.2 1.7e-06 27.7 4.2 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO75093.1 - 6.9e-06 25.9 4.9 6.9e-06 25.9 4.9 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDO75093.1 - 4.8e-05 23.4 3.5 4.8e-05 23.4 3.5 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CDO75093.1 - 0.0036 17.6 13.4 0.0036 17.6 13.4 2.7 2 1 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 CDO75093.1 - 0.012 15.5 1.2 0.012 15.5 1.2 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CDO75093.1 - 0.12 12.6 3.5 0.34 11.1 3.5 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CDO75093.1 - 1.1 9.1 13.1 0.75 9.6 3.3 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Peptidase_S10 PF00450.22 CDO75095.1 - 1.1e-44 153.5 0.8 7.7e-24 84.9 2.6 2.4 3 0 0 3 3 3 2 Serine carboxypeptidase CSTF2_hinge PF14327.6 CDO75095.1 - 3.8e-28 97.8 0.6 8.3e-28 96.7 0.6 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 CDO75095.1 - 3.4e-10 39.6 0.0 6.7e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 CDO75095.1 - 4.5e-10 39.0 5.6 9.8e-10 37.9 5.6 1.5 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal MCM PF00493.23 CDO75096.1 - 5.3e-100 333.1 0.0 7.5e-100 332.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CDO75096.1 - 1.3e-29 102.5 1.1 2.6e-29 101.5 1.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 CDO75096.1 - 1.1e-28 99.6 0.1 2.5e-28 98.4 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 CDO75096.1 - 6.4e-17 62.0 1.9 7.2e-17 61.9 0.0 2.1 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.14 CDO75096.1 - 4.4e-08 33.2 0.0 1.2e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CDO75096.1 - 2.1e-07 30.6 0.0 5.6e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CDO75096.1 - 0.00021 21.2 0.0 0.0034 17.2 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDO75096.1 - 0.00083 19.8 0.1 0.0036 17.7 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 CDO75096.1 - 0.0024 17.6 0.0 0.84 9.3 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain MMR_HSR1 PF01926.23 CDO75097.1 - 7.1e-20 71.2 0.0 1.5e-19 70.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 CDO75097.1 - 5.2e-09 35.9 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 GTP1/OBG cobW PF02492.19 CDO75097.1 - 0.0001 22.0 0.1 0.1 12.2 0.0 2.6 1 1 2 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 CDO75097.1 - 0.00015 21.3 0.0 0.00058 19.4 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CDO75097.1 - 0.00024 20.7 0.1 0.0038 16.8 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CDO75097.1 - 0.00035 20.1 0.0 0.49 9.8 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 CDO75097.1 - 0.00048 20.2 0.0 0.00072 19.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 CDO75097.1 - 0.0032 18.0 0.0 0.0084 16.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter MeaB PF03308.16 CDO75097.1 - 0.015 14.3 0.2 0.046 12.7 0.2 1.8 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CDO75097.1 - 0.016 15.7 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 CDO75097.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Ras PF00071.22 CDO75097.1 - 0.2 11.3 0.0 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 Ras family F-box-like PF12937.7 CDO75098.1 - 0.056 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 F-box-like RVT_1 PF00078.27 CDO75099.1 - 1.4e-16 60.7 0.0 2.6e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO75099.1 - 2.3e-07 31.1 0.0 8.2e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO75099.1 - 2e-05 25.2 0.0 4.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Ank_5 PF13857.6 CDO75103.1 - 1.2e-13 51.0 0.4 2.6e-09 37.2 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDO75103.1 - 6.3e-11 42.6 0.2 3.4e-06 27.5 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDO75103.1 - 7.6e-09 36.0 0.0 1.5e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDO75103.1 - 3.7e-08 33.5 0.2 9e-06 25.9 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 CDO75103.1 - 2.8e-07 30.3 0.2 0.00026 21.2 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat zf-MYND PF01753.18 CDO75103.1 - 3e-07 30.4 13.5 4.1e-06 26.8 10.5 2.3 2 0 0 2 2 2 1 MYND finger Na_sulph_symp PF00939.19 CDO75104.1 - 3.2e-33 115.5 30.9 4.4e-33 115.1 30.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 CDO75104.1 - 1.6e-28 100.8 21.9 1.2e-21 78.2 2.3 3.1 2 1 1 3 3 3 2 SPX domain MINDY_DUB PF04424.13 CDO75104.1 - 7.3e-28 96.9 0.0 2.3e-27 95.4 0.0 1.9 2 0 0 2 2 2 1 MINDY deubiquitinase CitMHS PF03600.16 CDO75104.1 - 1.9e-23 83.1 40.6 3.6e-16 59.2 18.8 2.4 1 1 1 2 2 2 2 Citrate transporter SAM_1 PF00536.30 CDO75105.1 - 0.0091 16.4 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CDO75105.1 - 0.032 14.3 0.1 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) KilA-N PF04383.13 CDO75106.1 - 0.18 11.7 0.2 1.4 8.8 0.2 2.1 1 1 0 1 1 1 0 KilA-N domain Orn_Arg_deC_N PF02784.16 CDO75107.1 - 8.3e-81 271.0 0.0 1.1e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CDO75107.1 - 2.4e-17 62.9 0.0 3.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.19 CDO75107.1 - 0.07 13.2 0.0 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain PTPA PF03095.15 CDO75108.1 - 2.8e-97 325.8 0.0 3.2e-97 325.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ku PF02735.16 CDO75109.1 - 1.3e-25 90.4 0.0 1e-24 87.4 0.0 2.2 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CDO75109.1 - 3.2e-24 85.9 0.0 6.8e-24 84.8 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CDO75109.1 - 5e-13 49.6 1.4 6.5e-10 39.6 0.1 2.6 2 0 0 2 2 2 2 Ku70/Ku80 C-terminal arm SAP PF02037.27 CDO75109.1 - 1.7e-08 34.0 0.0 4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 CDO75109.1 - 0.02 15.6 0.0 0.39 11.4 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain Glutaredoxin PF00462.24 CDO75110.1 - 7.1e-20 71.0 0.0 3.7e-18 65.5 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 CDO75110.1 - 1.1e-15 57.5 0.0 2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 CDO75110.1 - 1.1e-05 25.3 0.0 0.00013 21.9 0.0 2.3 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 CDO75110.1 - 1.7e-05 25.0 0.0 0.014 15.7 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CDO75110.1 - 0.00042 20.7 0.0 0.0076 16.7 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 CDO75110.1 - 0.0013 18.7 0.2 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain Phosducin PF02114.16 CDO75110.1 - 0.0054 15.7 0.0 0.0089 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosducin SH3BGR PF04908.15 CDO75110.1 - 0.012 15.7 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein TraF PF13728.6 CDO75110.1 - 0.026 14.4 0.6 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CDO75110.1 - 0.078 13.2 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like ADH_N PF08240.12 CDO75111.1 - 9.3e-14 51.2 0.1 2.3e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO75111.1 - 5.8e-12 45.7 0.1 6.4e-11 42.3 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO75111.1 - 2.3e-05 25.4 0.1 5.2e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CDO75111.1 - 2.5e-05 23.7 1.0 4.2e-05 22.9 1.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CDO75111.1 - 0.0018 17.6 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding PF02629.19 CDO75111.1 - 0.0033 18.1 0.4 2.2 9.0 0.0 2.6 2 0 0 2 2 2 2 CoA binding domain MVP_shoulder PF11978.8 CDO75111.1 - 0.023 14.7 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Shoulder domain ADH_N PF08240.12 CDO75112.1 - 1.3e-15 57.2 0.4 3.7e-15 55.7 0.2 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO75112.1 - 8.7e-14 51.6 0.0 2.2e-13 50.3 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO75112.1 - 7.8e-07 30.2 0.1 1.4e-06 29.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CDO75112.1 - 2e-05 24.0 0.9 3.5e-05 23.2 0.9 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CDO75112.1 - 0.00059 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 CDO75112.1 - 0.15 12.7 0.1 0.71 10.6 0.1 2.0 1 1 1 2 2 2 0 Methyltransferase domain Maf PF02545.14 CDO75113.1 - 2.3e-41 141.4 0.0 3.6e-41 140.8 0.0 1.3 1 1 0 1 1 1 1 Maf-like protein SLD3 PF08639.10 CDO75114.1 - 0.22 10.2 6.0 0.25 10.1 6.0 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Shisa PF13908.6 CDO75114.1 - 1.2 9.4 5.7 1.4 9.1 5.7 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Aminotran_1_2 PF00155.21 CDO75115.1 - 1e-16 61.1 0.0 1.4e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RNase_P_Rpp14 PF01900.19 CDO75116.1 - 7.8e-31 106.4 0.0 9.6e-31 106.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ABC_tran_Xtn PF12848.7 CDO75116.1 - 0.89 9.6 3.4 3.9 7.6 0.2 2.1 1 1 1 2 2 2 0 ABC transporter FAM153 PF15722.5 CDO75117.1 - 0.094 13.1 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 FAM153 family RabGAP-TBC PF00566.18 CDO75118.1 - 1.1e-49 169.0 0.0 1.7e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain AAA PF00004.29 CDO75120.1 - 3.7e-94 312.1 0.0 3.9e-47 160.0 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDO75120.1 - 5.5e-22 77.3 1.9 1.2e-10 41.0 0.4 2.9 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CDO75120.1 - 8.9e-15 54.8 0.0 1.6e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CDO75120.1 - 1.2e-11 45.3 4.8 0.0018 18.7 0.4 4.9 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 CDO75120.1 - 2.9e-11 43.8 0.8 0.016 15.5 0.1 5.1 2 2 2 4 4 4 2 AAA domain AAA_33 PF13671.6 CDO75120.1 - 3.6e-10 40.2 0.0 0.00012 22.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CDO75120.1 - 5e-10 39.5 0.5 0.0038 17.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CDO75120.1 - 5.9e-10 39.5 0.0 0.00061 19.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CDO75120.1 - 3.4e-09 36.4 0.0 7e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 CDO75120.1 - 4.8e-08 33.4 0.0 0.012 16.0 0.0 2.8 2 1 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 CDO75120.1 - 1.8e-07 31.3 0.0 0.022 14.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CDO75120.1 - 3.2e-07 30.0 0.2 0.019 14.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CDO75120.1 - 1e-06 28.6 0.0 0.055 13.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 CDO75120.1 - 1.4e-06 28.3 0.3 0.048 13.6 0.0 3.7 3 1 0 4 4 3 2 NACHT domain AAA_28 PF13521.6 CDO75120.1 - 3.8e-06 27.3 0.0 0.092 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 CDO75120.1 - 4.8e-06 26.5 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CDO75120.1 - 5.6e-06 26.4 0.0 0.076 13.0 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Vps4_C PF09336.10 CDO75120.1 - 1.1e-05 25.3 0.1 0.022 14.7 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 CDO75120.1 - 1.3e-05 25.8 0.0 0.26 11.8 0.0 3.0 3 1 0 3 3 2 2 ABC transporter AAA_18 PF13238.6 CDO75120.1 - 1.5e-05 25.5 0.0 0.3 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Cytidylate_kin2 PF13189.6 CDO75120.1 - 1.9e-05 24.9 0.0 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family ATPase PF06745.13 CDO75120.1 - 2.9e-05 23.5 0.4 1.1 8.6 0.0 3.6 3 1 0 4 4 4 2 KaiC Rad17 PF03215.15 CDO75120.1 - 3.4e-05 23.9 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain Zeta_toxin PF06414.12 CDO75120.1 - 6.3e-05 22.3 0.0 0.4 9.9 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_25 PF13481.6 CDO75120.1 - 7e-05 22.5 1.7 1.2 8.6 0.1 4.1 3 1 1 4 4 4 2 AAA domain Sigma54_activat PF00158.26 CDO75120.1 - 0.00014 21.6 0.0 0.57 9.9 0.0 3.3 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_17 PF13207.6 CDO75120.1 - 0.00016 22.1 0.0 0.28 11.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CDO75120.1 - 0.00016 20.9 0.0 0.019 14.1 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CDO75120.1 - 0.00026 20.6 0.0 0.79 9.2 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 CDO75120.1 - 0.00047 19.4 0.0 0.99 8.5 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.6 CDO75120.1 - 0.00049 20.2 0.0 3.2 7.9 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 CDO75120.1 - 0.00056 19.7 0.0 0.68 9.6 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CDO75120.1 - 0.00073 19.4 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain SKI PF01202.22 CDO75120.1 - 0.0015 18.7 0.0 2.2 8.4 0.0 2.9 3 0 0 3 3 2 1 Shikimate kinase Parvo_NS1 PF01057.17 CDO75120.1 - 0.0026 16.9 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 CDO75120.1 - 0.0029 17.5 0.0 3.8 7.3 0.0 2.9 2 1 0 2 2 2 1 Bacterial dnaA protein PhoH PF02562.16 CDO75120.1 - 0.003 17.0 0.3 2.8 7.3 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.6 CDO75120.1 - 0.0042 16.8 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CDO75120.1 - 0.0058 16.6 0.0 2.4 8.0 0.0 2.9 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CDO75120.1 - 0.0086 16.0 0.0 6.8 6.6 0.0 2.7 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 CDO75120.1 - 0.048 12.9 0.0 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AFG1_ATPase PF03969.16 CDO75120.1 - 0.048 12.5 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AAA_19 PF13245.6 CDO75120.1 - 0.051 13.9 1.2 19 5.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CDO75120.1 - 0.063 13.0 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 CDO75120.1 - 0.071 12.9 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Arnt_C PF18583.1 CDO75120.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain PreAtp-grasp PF18604.1 CDO75120.1 - 0.15 11.7 0.3 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Pre ATP-grasp domain Abhydrolase_6 PF12697.7 CDO75121.1 - 1.7e-25 90.9 0.2 1.7e-25 90.9 0.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO75121.1 - 1.2e-10 41.0 0.0 2.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDO75121.1 - 2e-09 37.5 0.0 3.1e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CDO75121.1 - 3e-05 24.3 0.0 9.8e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 CDO75121.1 - 0.042 13.6 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 CDO75121.1 - 0.042 13.5 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 CDO75121.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PRIMA1 PF16101.5 CDO75121.1 - 5.5 7.1 5.3 18 5.4 1.1 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 TPR_11 PF13414.6 CDO75122.1 - 2.4e-13 49.5 5.3 1.3e-08 34.4 1.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 CDO75122.1 - 8.1e-13 47.4 5.0 0.00058 19.8 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDO75122.1 - 1.5e-11 43.6 5.8 0.0063 16.3 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDO75122.1 - 6e-10 39.5 2.8 1.2e-07 32.1 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDO75122.1 - 2.4e-09 37.7 6.0 6.4e-06 26.7 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDO75122.1 - 4.1e-06 26.6 1.3 1.1 9.6 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDO75122.1 - 0.00025 21.6 14.6 0.0034 18.1 1.8 4.5 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO75122.1 - 0.002 18.0 3.2 0.82 9.8 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDO75122.1 - 0.0032 16.7 1.6 0.0075 15.5 1.6 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDO75122.1 - 0.028 14.6 2.9 0.11 12.7 2.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDO75122.1 - 0.029 14.4 3.3 2.4 8.3 0.1 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 CDO75122.1 - 0.036 14.5 3.4 0.5 10.8 3.4 2.5 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_12 PF13424.6 CDO75122.1 - 0.047 14.0 15.2 0.052 13.8 0.6 4.2 4 1 2 6 6 4 0 Tetratricopeptide repeat Phage_P2_GpE PF06528.12 CDO75122.1 - 0.074 12.6 0.2 0.074 12.6 0.2 2.3 2 0 0 2 2 2 0 Phage P2 GpE ANAPC3 PF12895.7 CDO75122.1 - 0.08 13.2 0.6 0.55 10.5 0.3 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HemY_N PF07219.13 CDO75122.1 - 0.18 12.0 3.3 8.7 6.6 0.2 2.7 2 0 0 2 2 2 0 HemY protein N-terminus TPR_6 PF13174.6 CDO75122.1 - 0.24 12.1 10.2 0.78 10.5 0.2 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat X PF00739.19 CDO75122.1 - 2.8 8.1 5.0 6.5 6.9 5.0 1.6 1 0 0 1 1 1 0 Trans-activation protein X MFS_1 PF07690.16 CDO75123.1 - 7.2e-26 90.9 44.1 1.1e-25 90.4 44.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO75123.1 - 3.5e-12 45.9 11.5 3.5e-12 45.9 11.5 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CDO75123.1 - 5.6e-06 25.1 9.3 5.6e-06 25.1 9.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Arrestin_N PF00339.29 CDO75124.1 - 3.5e-05 23.9 0.0 0.00012 22.1 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CDO75124.1 - 0.0092 16.4 0.0 0.15 12.6 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain KH_6 PF15985.5 CDO75124.1 - 0.3 11.5 1.0 0.63 10.4 1.0 1.5 1 0 0 1 1 1 0 KH domain FmdA_AmdA PF03069.15 CDO75125.1 - 3.2e-137 457.4 0.0 4e-137 457.0 0.0 1.1 1 0 0 1 1 1 1 Acetamidase/Formamidase family Aldedh PF00171.22 CDO75126.1 - 2.2e-60 204.5 0.0 2.3e-34 118.7 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family MukB_hinge PF16330.5 CDO75126.1 - 0.0055 16.4 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 MukB hinge domain Phage-scaffold PF09306.10 CDO75126.1 - 0.21 10.9 0.0 0.52 9.6 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein Macoilin PF09726.9 CDO75127.1 - 5.9 5.3 10.3 7.5 5.0 10.3 1.2 1 0 0 1 1 1 0 Macoilin family TetR PF13972.6 CDO75128.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial transcriptional repressor MBOAT PF03062.19 CDO75129.1 - 6.2e-16 58.7 6.4 6.2e-16 58.7 6.4 2.7 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family TrbC PF04956.13 CDO75129.1 - 0.2 11.9 3.1 0.78 10.0 0.1 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family CK_II_beta PF01214.18 CDO75130.1 - 2e-55 187.4 0.0 2.3e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4139 PF13598.6 CDO75131.1 - 8.2e-37 126.9 0.1 2.1e-36 125.6 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 CDO75131.1 - 4.1e-12 46.4 3.9 3.4e-09 37.0 0.3 2.9 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) DivIVA PF05103.13 CDO75131.1 - 0.0097 16.0 0.4 0.02 15.0 0.4 1.4 1 0 0 1 1 1 1 DivIVA protein DUF4094 PF13334.6 CDO75131.1 - 0.098 13.1 0.2 0.26 11.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) ABC_tran_CTD PF16326.5 CDO75131.1 - 0.32 11.3 2.8 0.67 10.2 2.8 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain Csm1_N PF18504.1 CDO75131.1 - 0.35 11.2 3.3 0.77 10.1 3.3 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF5462 PF17547.2 CDO75131.1 - 0.49 9.7 5.0 1.3 8.4 0.2 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5462) YscO PF07321.12 CDO75131.1 - 7.2 6.6 11.4 1.4 8.8 4.0 2.2 1 1 0 2 2 2 0 Type III secretion protein YscO DUF4139 PF13598.6 CDO75132.1 - 6.8e-33 114.1 0.0 4.8e-32 111.4 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DivIVA PF05103.13 CDO75132.1 - 0.013 15.6 0.1 0.035 14.2 0.1 1.6 1 0 0 1 1 1 0 DivIVA protein DUF4140 PF13600.6 CDO75132.1 - 0.048 14.1 6.2 32 5.1 6.2 2.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 CDO75132.1 - 0.92 9.3 3.1 1.7 8.5 0.3 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF3740 PF12548.8 CDO75132.1 - 4.6 7.7 6.7 2.4 8.6 3.4 2.1 2 1 0 2 2 2 0 Sulfatase protein CBP_BcsO PF17037.5 CDO75133.1 - 3 7.9 7.3 4 7.5 0.9 2.5 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsO Abhydrolase_6 PF12697.7 CDO75137.1 - 5.8e-16 59.8 1.2 7.5e-16 59.4 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.16 CDO75138.1 - 8.9e-38 130.1 57.7 7.3e-36 123.8 57.7 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO75138.1 - 1.5e-18 66.6 25.2 4.6e-17 61.7 25.1 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CDO75138.1 - 3.4e-12 46.0 10.7 3.4e-12 46.0 10.7 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter RVT_2 PF07727.14 CDO75139.1 - 4.1e-77 259.1 0.1 6.6e-77 258.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CDO75139.1 - 2.8e-23 82.1 0.3 1.2e-21 76.8 0.9 2.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type rve PF00665.26 CDO75139.1 - 7.2e-23 81.0 0.0 8.4e-21 74.4 0.0 2.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 CDO75139.1 - 1.9e-11 43.7 0.3 1e-10 41.3 0.0 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO75139.1 - 7.3e-05 22.5 0.0 0.00019 21.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 CDO75139.1 - 0.35 11.0 3.7 0.87 9.8 3.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Stealth_CR2 PF11380.8 CDO75140.1 - 4e-15 55.9 0.9 9.7e-13 48.2 0.1 2.5 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CDO75140.1 - 5.2e-07 29.5 0.8 1.4e-06 28.0 0.8 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 CDO75140.1 - 2.6e-05 23.9 0.2 6.6e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 DNA_pol_A_exo1 PF01612.20 CDO75141.1 - 1e-36 126.2 0.0 1.8e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CDO75141.1 - 5e-25 88.0 0.1 5.4e-24 84.7 0.1 2.3 2 0 0 2 2 2 1 PMC2NT (NUC016) domain TPR_1 PF00515.28 CDO75142.1 - 2.8e-16 58.6 3.5 1.5e-05 24.6 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.6 CDO75142.1 - 8.7e-14 51.8 0.0 1.1e-12 48.3 0.0 2.2 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 CDO75142.1 - 4.7e-13 48.2 6.1 0.00065 19.6 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDO75142.1 - 4e-10 40.2 11.1 2.4e-06 28.1 0.2 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO75142.1 - 3.5e-08 33.0 1.1 0.00078 19.1 0.1 3.0 1 1 2 3 3 3 3 TPR repeat TPR_19 PF14559.6 CDO75142.1 - 6.2e-07 29.8 3.8 1.6e-05 25.3 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDO75142.1 - 4.8e-06 26.6 3.3 2.3e-05 24.5 3.7 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDO75142.1 - 7.5e-06 25.8 0.3 0.21 11.9 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDO75142.1 - 6e-05 23.5 6.9 0.07 14.0 0.2 3.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO75142.1 - 0.00026 20.8 1.3 3.2 8.0 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDO75142.1 - 0.005 17.1 0.2 7.1 7.3 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDO75142.1 - 0.041 14.0 1.9 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 CDO75142.1 - 0.19 12.0 4.7 0.62 10.4 1.9 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CDO75142.1 - 1.1 9.2 3.4 3.4 7.7 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Retrotran_gag_2 PF14223.6 CDO75143.1 - 3.3e-27 94.8 0.0 4.4e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 CDO75143.1 - 0.0046 17.2 0.0 0.0069 16.6 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein gag_pre-integrs PF13976.6 CDO75144.1 - 3.1e-09 36.5 0.0 6.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 CDO75144.1 - 2.4e-06 27.7 0.0 5.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 CDO75144.1 - 0.016 15.3 0.6 0.032 14.3 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 CDO75145.1 - 0.00034 20.3 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Bac_rhodopsin PF01036.18 CDO75147.1 - 3e-35 121.8 24.5 4.5e-35 121.2 24.5 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Ferric_reduct PF01794.19 CDO75148.1 - 6.7e-21 74.7 7.0 6.7e-21 74.7 7.0 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CDO75148.1 - 8e-11 42.3 0.0 4.3e-10 39.9 0.0 2.2 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CDO75148.1 - 2.9e-10 40.2 0.0 4.9e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain DUF4149 PF13664.6 CDO75148.1 - 0.8 10.1 4.4 0.37 11.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Ctr PF04145.15 CDO75149.1 - 7.8e-29 101.2 0.1 1e-28 100.8 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Aldo_ket_red PF00248.21 CDO75151.1 - 1.6e-22 80.1 0.0 3.2e-22 79.1 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Cupin_8 PF13621.6 CDO75153.1 - 9.2e-54 182.8 0.0 1.6e-53 182.1 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CDO75153.1 - 0.0012 18.4 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Taxilin PF09728.9 CDO75154.1 - 0.015 14.5 4.1 0.02 14.1 4.1 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF3450 PF11932.8 CDO75154.1 - 0.026 13.8 2.9 0.037 13.3 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HAP1_N PF04849.13 CDO75154.1 - 0.62 9.2 6.6 0.46 9.6 1.6 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region GIT_CC PF16559.5 CDO75154.1 - 2.5 8.0 7.9 14 5.7 0.6 2.8 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor SlyX PF04102.12 CDO75154.1 - 8.6 7.1 7.3 33 5.2 6.7 2.2 1 1 1 2 2 2 0 SlyX DUF3808 PF10300.9 CDO75156.1 - 1.8e-65 221.6 0.7 5.5e-41 140.8 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3808) Glyco_hydro_38N PF01074.22 CDO75156.1 - 2.5e-61 207.6 0.0 1.5e-54 185.3 0.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CDO75156.1 - 1e-46 159.7 0.0 1.6e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 CDO75156.1 - 8e-07 29.1 0.1 1.5e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain TPR_12 PF13424.6 CDO75156.1 - 0.12 12.7 6.0 8.5 6.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDO75156.1 - 0.31 11.4 4.1 44 4.7 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDO75156.1 - 1.2 9.0 5.5 9.2 6.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDO75156.1 - 1.6 9.8 7.0 74 4.6 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TEA PF01285.18 CDO75157.1 - 1.3e-22 79.6 0.0 2.6e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain SLAC1 PF03595.17 CDO75158.1 - 3.6e-52 177.6 47.2 4.4e-52 177.3 47.2 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel IBR PF01485.21 CDO75159.1 - 1.9e-07 31.2 31.3 9.6e-05 22.5 5.0 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Acyl_transf_1 PF00698.21 CDO75159.1 - 0.18 11.2 0.3 0.37 10.2 0.3 1.4 1 0 0 1 1 1 0 Acyl transferase domain DNA_ligase_ZBD PF03119.16 CDO75159.1 - 6.6 6.8 14.6 0.048 13.7 1.5 3.6 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain RRM_1 PF00076.22 CDO75163.1 - 4.3e-15 55.3 0.0 1.1e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CDO75163.1 - 0.0048 17.2 0.0 0.0048 17.2 0.0 3.2 2 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 CDO75163.1 - 0.053 13.6 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CDO75163.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 CDO75163.1 - 0.17 11.9 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 RL domain TPR_2 PF07719.17 CDO75164.1 - 3.4e-26 89.2 5.3 0.00047 20.0 0.0 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO75164.1 - 6.6e-21 74.3 1.3 9.4e-10 38.6 0.0 4.9 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CDO75164.1 - 1.3e-20 72.3 1.7 0.00057 19.6 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 CDO75164.1 - 4.9e-14 52.4 7.7 9.2e-09 35.5 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDO75164.1 - 1.2e-11 43.8 2.7 0.0014 18.7 0.0 6.6 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO75164.1 - 1.8e-11 44.4 3.4 0.19 12.2 0.6 6.9 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CDO75164.1 - 3.1e-08 33.4 1.4 0.0018 17.7 0.4 3.7 2 1 1 3 3 3 2 MalT-like TPR region TPR_16 PF13432.6 CDO75164.1 - 3.9e-08 33.8 8.2 0.0028 18.3 0.0 5.9 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO75164.1 - 2.2e-06 27.3 10.6 0.12 12.5 0.1 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDO75164.1 - 3.7e-06 26.6 8.3 0.00089 19.0 0.2 6.2 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 CDO75164.1 - 3.8e-06 26.5 1.9 0.01 15.5 0.0 5.7 6 1 1 7 7 6 1 TPR repeat TPR_14 PF13428.6 CDO75164.1 - 2e-05 25.0 6.4 2 9.5 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 CDO75164.1 - 0.00014 22.1 3.0 2.4 9.0 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CDO75164.1 - 0.0031 17.8 5.8 7 7.3 0.0 6.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDO75164.1 - 0.022 15.4 16.8 1.8 9.4 0.1 6.6 9 0 0 9 9 7 0 Tetratricopeptide repeat Coatomer_E PF04733.14 CDO75164.1 - 0.031 13.7 0.6 3.9 6.8 0.2 3.1 2 1 1 3 3 3 0 Coatomer epsilon subunit PhnG PF06754.12 CDO75165.1 - 0.0016 18.4 0.6 0.45 10.4 0.3 2.2 2 0 0 2 2 2 2 Phosphonate metabolism protein PhnG Maf1 PF09174.10 CDO75166.1 - 1.9e-40 138.8 1.1 1.1e-33 116.8 0.2 2.2 2 0 0 2 2 2 2 Maf1 regulator XRCC4 PF06632.12 CDO75166.1 - 0.1 11.4 0.8 0.15 10.9 0.8 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 B12D PF06522.11 CDO75167.1 - 0.05 13.4 1.9 0.12 12.2 1.9 1.7 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit TMEM238 PF15125.6 CDO75167.1 - 1 9.6 5.5 0.25 11.5 1.2 1.9 1 1 1 2 2 2 0 TMEM238 protein family Sugar_tr PF00083.24 CDO75168.1 - 3.9e-38 131.5 17.9 1.8e-36 126.0 17.9 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO75168.1 - 2.1e-15 56.5 23.6 2.1e-15 56.5 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SCP2 PF02036.17 CDO75169.1 - 1.2e-24 86.7 1.1 1.5e-24 86.4 1.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CDO75169.1 - 0.00043 20.6 0.3 0.00055 20.2 0.3 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Rep_fac_C PF08542.11 CDO75169.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Replication factor C C-terminal domain DHDPS PF00701.22 CDO75170.1 - 6.7e-41 139.9 0.0 8e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Dynamin_N PF00350.23 CDO75171.1 - 5.9e-44 150.1 0.0 1.1e-43 149.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 CDO75171.1 - 4.1e-13 49.2 0.0 1e-12 47.9 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region 4HBT_2 PF13279.6 CDO75171.1 - 2.3e-07 31.3 0.0 2.6e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 Thioesterase-like superfamily MMR_HSR1 PF01926.23 CDO75171.1 - 3e-05 24.1 0.0 7.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 CDO75171.1 - 0.046 13.5 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDO75171.1 - 0.091 12.5 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain Na_Ca_ex PF01699.24 CDO75173.1 - 1.4e-47 161.4 37.3 2.7e-28 98.8 12.1 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Plasmodium_Vir PF05795.11 CDO75173.1 - 0.021 14.2 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4381 PF14316.6 CDO75173.1 - 0.85 9.9 4.3 11 6.3 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Abhydrolase_1 PF00561.20 CDO75174.1 - 3e-16 59.9 0.2 2.8e-14 53.4 0.3 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO75174.1 - 5e-16 58.7 0.6 7e-15 54.9 0.6 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO75174.1 - 8.6e-16 59.2 0.9 1e-15 58.9 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CDO75174.1 - 0.00061 19.3 0.2 0.38 10.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 CDO75174.1 - 0.047 13.2 0.1 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family FH2 PF02181.23 CDO75175.1 - 0.003 16.7 0.1 0.1 11.7 0.0 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain GMC_oxred_N PF00732.19 CDO75176.1 - 4e-64 216.8 0.0 4.9e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CDO75176.1 - 3.8e-06 26.2 0.1 5.6e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CDO75176.1 - 2.1e-05 23.8 0.0 0.012 14.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CDO75176.1 - 0.00012 21.8 0.1 0.0059 16.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDO75176.1 - 0.00012 21.4 0.0 0.00032 20.0 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 CDO75176.1 - 0.00027 21.1 0.1 0.00058 20.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDO75176.1 - 0.00057 19.2 0.0 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDO75176.1 - 0.0098 14.6 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GDI PF00996.18 CDO75176.1 - 0.07 11.6 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor eIF3_subunit PF08597.10 CDO75177.1 - 1.4e-58 198.7 19.9 1.7e-58 198.4 19.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF2935 PF11155.8 CDO75177.1 - 0.047 14.0 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Pex26 PF07163.12 CDO75177.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Pex26 protein WD40 PF00400.32 CDO75178.1 - 1.6e-15 57.2 6.7 0.0027 18.5 0.2 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 CDO75178.1 - 0.27 9.8 1.6 0.71 8.4 0.1 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Glyco_hydro_10 PF00331.20 CDO75179.1 - 1.6e-72 244.4 0.0 4.3e-42 144.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 CBM_1 PF00734.18 CDO75179.1 - 1.1e-13 50.9 10.2 1.1e-13 50.9 10.2 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain CRIM PF16978.5 CDO75179.1 - 0.084 13.0 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain adh_short PF00106.25 CDO75180.1 - 1.3e-22 80.2 0.1 1.7e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO75180.1 - 2e-19 70.1 0.1 2.5e-19 69.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.15 CDO75180.1 - 0.0074 16.2 0.1 0.047 13.6 0.1 2.0 2 0 0 2 2 2 1 YjeF-related protein N-terminus 3HCDH_N PF02737.18 CDO75180.1 - 0.019 14.9 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HEM4 PF02602.15 CDO75180.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Glyco_hydro_10 PF00331.20 CDO75181.1 - 1.7e-42 145.7 0.0 1.9e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 MetOD1 PF18546.1 CDO75181.1 - 0.021 14.8 0.1 0.037 14.0 0.1 1.5 1 1 0 1 1 1 0 Metanogen output domain 1 CRIM PF16978.5 CDO75181.1 - 0.024 14.8 0.0 0.03 14.4 0.0 1.1 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain Glyco_hydro_10 PF00331.20 CDO75182.1 - 3.3e-60 203.9 0.0 4.1e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 CDO75182.1 - 2.5e-15 56.1 9.8 2.5e-15 56.1 9.8 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Cellulase PF00150.18 CDO75182.1 - 0.045 13.2 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Cas9_PI2 PF18070.1 CDO75182.1 - 0.17 12.6 0.1 0.36 11.6 0.1 1.5 1 0 0 1 1 1 0 CRISPR-Cas9 PI domain Cation_ATPase_C PF00689.21 CDO75183.1 - 3.1e-47 160.6 3.2 3.1e-47 160.6 3.2 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CDO75183.1 - 4.7e-39 133.8 0.2 4.7e-39 133.8 0.2 2.5 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 CDO75183.1 - 1.3e-22 79.7 0.0 3.1e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CDO75183.1 - 5.9e-16 59.4 0.5 3.1e-15 57.0 0.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDO75183.1 - 6.2e-07 29.0 0.0 1.9e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDO75183.1 - 0.00037 20.3 1.9 0.0086 15.8 0.2 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PEX11 PF05648.14 CDO75184.1 - 4.3e-07 29.6 0.3 6.2e-05 22.6 0.3 2.0 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) ATG22 PF11700.8 CDO75187.1 - 3e-113 379.0 21.0 4.2e-113 378.5 21.0 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Mitofilin PF09731.9 CDO75188.1 - 2.5e-114 383.4 14.0 3.4e-114 382.9 14.0 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein GBP_C PF02841.14 CDO75188.1 - 0.12 11.8 19.6 0.068 12.6 13.0 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DUF494 PF04361.13 CDO75188.1 - 0.21 11.5 5.5 0.43 10.5 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Histidinol_dh PF00815.20 CDO75188.1 - 1.2 8.0 12.6 0.14 11.1 2.3 2.3 2 0 0 2 2 2 0 Histidinol dehydrogenase ABC_membrane PF00664.23 CDO75190.1 - 2.4e-41 142.2 14.5 3.8e-30 105.5 0.8 3.3 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDO75190.1 - 1.2e-06 29.1 0.0 2.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter DUF1398 PF07166.11 CDO75190.1 - 0.044 13.9 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) Trehalase PF01204.18 CDO75191.1 - 4.3e-156 520.7 0.1 5.4e-156 520.4 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CDO75191.1 - 6e-14 51.5 0.1 1e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Lipase_3 PF01764.25 CDO75192.1 - 6.3e-07 29.3 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 CDO75192.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 CDO75192.1 - 0.14 12.7 0.0 0.14 12.7 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family RVT_1 PF00078.27 CDO75194.1 - 1e-35 123.3 0.0 1.5e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO75194.1 - 9.5e-10 38.8 0.0 2.2e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 CDO75194.1 - 0.0024 18.5 0.4 0.0068 17.1 0.4 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase TB2_DP1_HVA22 PF03134.19 CDO75195.1 - 2.6e-11 43.3 0.5 4.6e-11 42.5 0.5 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family G10 PF01125.17 CDO75196.1 - 1.7e-69 232.2 5.6 1.9e-69 232.0 5.6 1.0 1 0 0 1 1 1 1 G10 protein RelB_N PF18506.1 CDO75196.1 - 0.12 12.2 0.3 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 RelB Antitoxin alpha helical domain MFS_1 PF07690.16 CDO75197.1 - 4.9e-36 124.4 28.4 4.9e-36 124.4 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO75197.1 - 3.6e-12 45.9 21.0 9.6e-12 44.5 21.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CDO75197.1 - 7.3e-06 24.7 0.8 1.2e-05 24.0 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Lig_chan PF00060.26 CDO75197.1 - 0.1 12.5 0.2 1.1 9.0 0.1 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel OATP PF03137.20 CDO75197.1 - 0.29 9.4 5.8 0.32 9.2 1.9 2.4 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 CDO75198.1 - 3.2e-63 214.1 0.0 4.1e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BTP PF05232.12 CDO75198.1 - 1.9 8.6 4.6 1.1 9.4 1.4 2.1 2 0 0 2 2 2 0 Chlorhexidine efflux transporter WD40 PF00400.32 CDO75199.1 - 5.5e-31 106.1 17.7 2.2e-07 31.4 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 CDO75199.1 - 2.5e-13 49.7 0.5 6.9e-13 48.3 0.5 1.8 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CDO75199.1 - 2.1e-07 31.1 0.4 1.4 9.2 0.0 5.6 1 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CDO75199.1 - 3.6e-05 22.6 1.6 0.8 8.3 0.0 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.33 CDO75199.1 - 0.00012 21.9 0.3 0.00027 20.7 0.3 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 CDO75199.1 - 0.012 15.0 0.0 5.9 6.1 0.0 2.6 2 1 0 2 2 2 0 WD40-like domain SWIM PF04434.17 CDO75199.1 - 0.21 11.3 1.1 0.35 10.6 0.2 1.9 2 0 0 2 2 2 0 SWIM zinc finger p450 PF00067.22 CDO75200.1 - 2e-29 102.7 0.0 2.5e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.27 CDO75201.1 - 0.0043 16.6 0.0 0.0078 15.8 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) p450 PF00067.22 CDO75203.1 - 6.4e-11 41.7 0.0 3.8e-06 25.9 0.0 3.9 3 1 1 4 4 4 4 Cytochrome P450 Mem_trans PF03547.18 CDO75204.1 - 1.7e-28 99.1 2.1 2.6e-28 98.5 2.1 1.3 1 0 0 1 1 1 1 Membrane transport protein Peptidase_M49 PF03571.15 CDO75205.1 - 6.2e-208 691.6 0.0 7.6e-208 691.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 TauD PF02668.16 CDO75206.1 - 1.2e-43 149.8 0.1 1.9e-43 149.2 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family His_Phos_2 PF00328.22 CDO75209.1 - 7.2e-30 104.6 0.0 8e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pyr_redox_2 PF07992.14 CDO75211.1 - 5.9e-15 55.3 0.0 2.3e-12 46.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDO75211.1 - 1.6e-12 47.3 0.0 7.7e-10 38.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 CDO75211.1 - 9.7e-12 44.1 0.0 1.4e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like DAO PF01266.24 CDO75211.1 - 2e-07 31.0 5.1 0.0017 18.0 1.5 3.8 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDO75211.1 - 1.1e-06 28.8 2.1 4.4e-05 23.6 0.1 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CDO75211.1 - 1.8e-06 27.4 0.0 0.0056 16.0 0.0 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDO75211.1 - 1.3e-05 25.7 0.7 0.0019 18.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO75211.1 - 1.8e-05 24.7 0.2 1 9.4 0.0 3.7 2 2 0 3 3 3 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 CDO75211.1 - 0.00025 20.5 0.1 0.84 8.9 0.0 2.7 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.22 CDO75211.1 - 0.00036 19.7 0.5 0.16 11.0 0.0 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 CDO75211.1 - 0.0018 18.7 0.0 0.069 13.6 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CDO75211.1 - 0.003 17.6 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 CDO75211.1 - 0.0055 15.8 3.8 0.029 13.4 0.3 2.7 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 CDO75211.1 - 0.008 15.4 0.0 0.19 10.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 CDO75211.1 - 0.01 14.6 0.8 4.5 5.9 0.1 3.7 4 0 0 4 4 4 1 HI0933-like protein DUF4419 PF14388.6 CDO75212.1 - 5e-29 101.7 0.0 6.3e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Ubiq_cyt_C_chap PF03981.12 CDO75213.1 - 2e-27 96.0 0.1 8e-14 51.9 0.0 3.0 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Cpn60_TCP1 PF00118.24 CDO75214.1 - 1e-83 281.7 11.1 1.6e-83 281.0 11.1 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family polyprenyl_synt PF00348.17 CDO75215.1 - 1.6e-40 138.8 0.0 2.1e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF2795 PF11387.8 CDO75215.1 - 0.042 14.1 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) Epimerase PF01370.21 CDO75217.1 - 3e-18 66.2 0.0 1.2e-17 64.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDO75217.1 - 1.3e-14 54.4 0.0 4.4e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDO75217.1 - 1.5e-14 53.7 0.0 2.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CDO75217.1 - 3.6e-12 46.0 0.0 2.3e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CDO75217.1 - 1.6e-11 44.4 0.3 2.8e-11 43.7 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CDO75217.1 - 5.1e-06 25.8 0.0 7.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 CDO75217.1 - 0.001 19.0 0.7 0.0027 17.7 0.7 1.8 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 CDO75217.1 - 0.0027 17.2 1.2 0.0072 15.8 0.6 2.0 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 CDO75218.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TAFII28 PF04719.14 CDO75219.1 - 0.071 13.2 0.1 2.7 8.1 0.0 2.3 2 0 0 2 2 2 0 hTAFII28-like protein conserved region YWFCY PF14293.6 CDO75219.1 - 3.3 8.1 4.4 19 5.7 0.2 2.2 2 0 0 2 2 2 0 YWFCY protein Pkinase_fungal PF17667.1 CDO75220.1 - 0.0019 17.0 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Chromo PF00385.24 CDO75221.1 - 3.6e-07 30.0 0.0 6.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CDO75221.1 - 0.0085 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Chromo shadow domain RT_RNaseH PF17917.1 CDO75222.1 - 2.2e-36 124.3 0.0 4.5e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO75222.1 - 2.9e-32 110.7 0.0 5.5e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO75222.1 - 2.3e-31 109.0 0.0 4.3e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDO75222.1 - 1.8e-21 76.0 0.3 3.7e-21 75.0 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO75222.1 - 1.4e-09 38.2 0.0 3.5e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 CDO75222.1 - 7.1e-08 32.9 0.0 1.4e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO75222.1 - 2.9e-07 31.0 0.0 6.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CDO75222.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 CDO75222.1 - 0.0043 17.2 0.1 0.0085 16.3 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger LisH_TPL PF17814.1 CDO75222.1 - 0.053 13.2 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 LisH-like dimerisation domain Retrotrans_gag PF03732.17 CDO75223.1 - 0.03 14.6 2.4 0.03 14.6 2.4 2.4 1 1 1 2 2 2 0 Retrotransposon gag protein DUF2183 PF09949.9 CDO75224.1 - 2.7e-20 72.5 0.0 4.8e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF5525 PF17663.1 CDO75224.1 - 1.8 6.5 10.4 2.5 6.0 10.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) DEC-1_N PF04625.13 CDO75224.1 - 9.8 5.1 13.7 3 6.8 10.8 1.5 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Pkinase PF00069.25 CDO75226.1 - 5.3e-07 29.3 0.0 7.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PHP_C PF13263.6 CDO75226.1 - 0.086 12.6 0.0 0.4 10.5 0.0 2.2 1 0 0 1 1 1 0 PHP-associated GyrI-like PF06445.15 CDO75226.1 - 0.2 12.0 0.1 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 GyrI-like small molecule binding domain Pkinase PF00069.25 CDO75227.1 - 1.3e-07 31.3 0.0 3.5e-07 29.8 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75227.1 - 0.0035 16.7 0.0 0.018 14.3 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase IML1 PF12257.8 CDO75228.1 - 2.1e-108 361.8 0.0 3e-108 361.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 CDO75228.1 - 1.1e-12 47.8 0.0 2.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf_CCCH_5 PF18384.1 CDO75228.1 - 0.28 11.3 0.9 0.58 10.3 0.9 1.5 1 0 0 1 1 1 0 Unkempt Zinc finger domain 1 (Znf1) DUF4699 PF15770.5 CDO75228.1 - 0.29 10.8 1.2 0.59 9.8 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) F-box-like PF12937.7 CDO75229.1 - 8.4e-09 35.2 0.4 2.2e-08 33.8 0.4 1.8 1 0 0 1 1 1 1 F-box-like DUF3506 PF12014.8 CDO75229.1 - 4.2e-08 33.3 0.1 2.4e-05 24.4 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box PF00646.33 CDO75229.1 - 6.3e-05 22.7 0.3 0.00013 21.7 0.3 1.5 1 0 0 1 1 1 1 F-box domain Clathrin PF00637.20 CDO75230.1 - 4.6e-20 71.9 0.1 1.1e-19 70.7 0.1 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_1 PF10366.9 CDO75230.1 - 0.0021 18.3 0.5 0.017 15.4 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.6 CDO75230.1 - 0.0028 17.9 2.1 0.0042 17.4 0.9 1.9 2 0 0 2 2 2 1 Ring finger domain Vps39_2 PF10367.9 CDO75230.1 - 0.0049 17.3 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 CDO75230.1 - 0.0055 16.7 2.9 0.013 15.6 2.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CDO75230.1 - 0.092 12.7 0.3 0.23 11.5 0.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDO75230.1 - 0.1 12.5 1.0 0.22 11.4 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO75230.1 - 0.1 12.5 0.9 0.22 11.5 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDO75230.1 - 0.14 12.2 1.1 0.3 11.2 1.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CDO75230.1 - 0.23 11.1 1.1 1 9.0 0.5 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type CENP-B_dimeris PF09026.10 CDO75230.1 - 3.1 8.2 12.7 8 6.9 12.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tugs PF17840.1 CDO75232.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain RPN7 PF10602.9 CDO75233.1 - 3e-56 189.9 0.6 4.1e-56 189.4 0.6 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CDO75233.1 - 2.4e-15 56.9 0.0 6.8e-15 55.5 0.0 1.8 1 1 0 1 1 1 1 PCI domain TPR_15 PF13429.6 CDO75233.1 - 0.0087 15.3 0.3 0.018 14.3 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDO75233.1 - 0.026 14.6 0.4 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat FeoB_Cyto PF17910.1 CDO75233.1 - 0.19 12.3 1.8 0.53 10.9 1.8 1.8 1 0 0 1 1 1 0 FeoB cytosolic helical domain TPR_12 PF13424.6 CDO75233.1 - 0.44 10.9 3.8 0.56 10.5 2.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN6_N PF18055.1 CDO75234.1 - 2.8e-43 147.0 2.1 2.8e-43 147.0 2.1 2.2 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CDO75234.1 - 1.6e-19 70.4 0.4 4.7e-19 68.8 0.3 1.9 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 CDO75234.1 - 1.3e-10 40.8 0.4 3.6e-10 39.4 0.4 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 CDO75234.1 - 0.0069 16.3 6.9 0.027 14.5 0.1 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CDO75234.1 - 0.01 15.3 1.1 0.01 15.3 1.1 2.5 3 0 0 3 3 3 1 MalT-like TPR region DDRGK PF09756.9 CDO75234.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 DDRGK domain TPR_2 PF07719.17 CDO75234.1 - 0.12 12.6 8.3 6.9 7.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDO75234.1 - 1.3 9.5 5.7 23 5.5 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat RPN6_C_helix PF18503.1 CDO75235.1 - 4.1e-05 23.2 0.1 9.9e-05 22.0 0.1 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain Fib_alpha PF08702.10 CDO75238.1 - 0.04 14.1 0.8 0.057 13.6 0.8 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RNA_binding PF01877.17 CDO75238.1 - 0.13 12.6 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 RNA binding BDV_P40 PF06407.11 CDO75238.1 - 0.13 11.4 0.0 0.44 9.6 0.0 1.8 2 0 0 2 2 2 0 Borna disease virus P40 protein Med21 PF11221.8 CDO75238.1 - 0.26 11.5 3.7 0.76 10.0 3.7 1.8 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF543 PF04418.12 CDO75241.1 - 0.13 12.3 2.2 0.3 11.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF543) BTB PF00651.31 CDO75242.1 - 0.00018 21.7 0.0 0.00045 20.4 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain PEMT PF04191.13 CDO75243.1 - 3e-33 114.4 2.2 8.1e-33 113.0 1.7 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase MFS_1 PF07690.16 CDO75244.1 - 1.4e-28 99.9 38.7 1.1e-26 93.6 38.6 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC1 PF03109.16 CDO75244.1 - 5.9e-16 58.7 0.0 1.2e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Sugar_tr PF00083.24 CDO75244.1 - 1.1e-08 34.4 14.0 1.1e-08 34.4 14.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CDO75244.1 - 9.5e-07 27.6 6.7 1.7e-06 26.8 6.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phosphorylase PF00343.20 CDO75246.1 - 8e-292 969.8 0.0 1.4e-288 959.1 0.0 2.1 1 1 0 1 1 1 1 Carbohydrate phosphorylase ETC_C1_NDUFA5 PF04716.14 CDO75248.1 - 4.6e-24 84.0 0.4 6.1e-24 83.6 0.4 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region RPN6_C_helix PF18503.1 CDO75248.1 - 0.026 14.2 0.4 0.047 13.4 0.4 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain LSM PF01423.22 CDO75249.1 - 2.8e-05 23.7 0.0 4.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 LSM domain PHD PF00628.29 CDO75250.1 - 2.2e-09 37.0 9.0 2.2e-09 37.0 9.0 2.2 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.8 CDO75250.1 - 0.0059 16.4 0.3 0.0059 16.4 0.3 2.2 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain PHD_4 PF16866.5 CDO75250.1 - 3.3 7.9 8.2 7.7 6.7 8.2 1.7 1 0 0 1 1 1 0 PHD-finger HABP4_PAI-RBP1 PF04774.15 CDO75251.1 - 6e-13 49.6 11.1 6e-13 49.6 11.1 2.9 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family His_Phos_1 PF00300.22 CDO75252.1 - 4.7e-22 78.6 0.0 6.4e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Memo PF01875.17 CDO75253.1 - 1.5e-71 240.8 0.0 1.7e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Ribosomal_L32e PF01655.18 CDO75254.1 - 1.2e-50 170.4 1.3 1.4e-50 170.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Pkinase PF00069.25 CDO75255.1 - 5.5e-41 140.7 0.0 3.3e-39 134.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75255.1 - 5.6e-17 61.9 0.0 1.7e-15 57.0 0.0 2.7 3 1 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO75255.1 - 1.2e-06 28.1 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDO75255.1 - 0.00025 20.5 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO75255.1 - 0.0036 17.3 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO75255.1 - 0.19 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase GTP_EFTU PF00009.27 CDO75256.1 - 6.1e-47 159.7 0.0 1.1e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDO75256.1 - 1.9e-42 144.1 0.0 4.9e-42 142.8 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDO75256.1 - 1.5e-14 54.1 0.7 1.5e-14 54.1 0.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDO75256.1 - 0.00098 19.2 0.1 0.024 14.7 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CDO75256.1 - 0.0073 16.2 2.0 0.0095 15.8 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 CDO75256.1 - 0.12 12.4 0.2 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain DLH PF01738.18 CDO75257.1 - 8.3e-06 25.5 0.0 0.046 13.3 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Acetyltransf_1 PF00583.25 CDO75258.1 - 0.0098 16.1 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4227 PF14004.6 CDO75258.1 - 0.066 13.2 0.1 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) Acetyltransf_CG PF14542.6 CDO75258.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Abhydrolase_1 PF00561.20 CDO75259.1 - 5.2e-14 52.5 0.2 2.8e-07 30.4 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO75259.1 - 1.1e-07 31.4 0.9 0.0036 16.6 0.2 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 CDO75259.1 - 1.9e-05 24.7 0.0 2.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.7 CDO75259.1 - 3.3e-05 24.6 5.6 0.00012 22.7 5.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CDO75259.1 - 0.00025 20.8 0.2 0.078 12.7 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CDO75259.1 - 0.00053 19.8 0.0 0.69 9.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 CDO75259.1 - 0.0031 17.2 0.0 0.0059 16.3 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CDO75259.1 - 0.0061 16.1 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family UPF0227 PF05728.12 CDO75259.1 - 0.02 14.8 0.1 0.99 9.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.21 CDO75259.1 - 0.02 14.3 0.1 0.11 11.9 0.1 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Elong_Iki1 PF10483.9 CDO75260.1 - 4.3e-09 36.3 1.2 0.0003 20.4 0.0 2.3 2 1 0 2 2 2 2 Elongator subunit Iki1 Aminotran_1_2 PF00155.21 CDO75262.1 - 2.8e-88 296.5 0.0 3.2e-88 296.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2 PF00152.20 CDO75263.1 - 1e-78 264.6 0.0 1.4e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CDO75263.1 - 1.2e-08 34.8 0.0 2.3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDO75263.1 - 0.014 14.9 0.4 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) eIF3_subunit PF08597.10 CDO75263.1 - 0.2 11.5 8.0 0.35 10.8 8.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SPRY PF00622.28 CDO75265.1 - 3.3e-18 65.9 0.0 5.2e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 SPRY domain DUF4448 PF14610.6 CDO75265.1 - 0.011 15.5 0.0 0.95 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) CBS PF00571.28 CDO75266.1 - 1.9e-24 85.9 2.5 3.3e-10 40.2 0.0 4.5 4 0 0 4 4 4 4 CBS domain Mito_carr PF00153.27 CDO75267.1 - 3.6e-58 193.5 0.4 2.3e-18 65.9 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein RhoGEF PF00621.20 CDO75268.1 - 4.3e-42 144.4 0.0 6.4e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 CDO75268.1 - 4.8e-11 42.3 6.0 3.8e-07 29.8 1.4 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CDO75268.1 - 6.5e-06 26.4 7.5 0.0065 16.9 0.7 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDO75268.1 - 0.12 13.0 6.7 14 6.7 0.2 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat G-alpha PF00503.20 CDO75270.1 - 1.6e-70 238.1 0.0 2.8e-70 237.3 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDO75270.1 - 2.2e-06 27.2 0.0 4.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family UDPGT PF00201.18 CDO75271.1 - 8.5e-20 71.0 0.1 1.4e-19 70.3 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO75271.1 - 0.00022 21.3 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain IBR PF01485.21 CDO75272.1 - 2.3e-12 47.0 44.4 6.5e-09 35.9 17.7 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 CDO75272.1 - 9.6e-05 22.2 4.6 9.6e-05 22.2 4.6 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO75272.1 - 0.00014 21.7 7.8 0.00014 21.7 7.8 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO75272.1 - 0.027 14.8 7.8 0.027 14.8 7.8 3.8 3 1 0 3 3 3 0 Ring finger domain zf-RING_4 PF14570.6 CDO75272.1 - 4.9 7.0 21.8 11 5.9 6.2 3.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain HSP70 PF00012.20 CDO75273.1 - 9.4e-163 542.6 1.0 9.4e-163 542.6 1.0 1.7 1 1 1 2 2 2 1 Hsp70 protein tRNA-synt_2 PF00152.20 CDO75273.1 - 1.2e-71 241.4 0.0 2.6e-71 240.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) MreB_Mbl PF06723.13 CDO75273.1 - 7.5e-11 41.4 0.2 4.7e-10 38.8 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein tRNA_anti-codon PF01336.25 CDO75273.1 - 2.4e-10 40.2 0.0 1.5e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDO75273.1 - 2.4e-08 33.8 0.2 0.0019 17.7 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Aminopep PF10023.9 CDO75273.1 - 1.2 8.4 8.0 0.72 9.1 2.3 2.3 1 1 1 2 2 2 0 Putative aminopeptidase DUF4363 PF14276.6 CDO75273.1 - 6.2 7.0 5.9 13 6.0 2.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) WD40 PF00400.32 CDO75275.1 - 1.7e-07 31.8 8.2 0.056 14.3 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75275.1 - 0.00056 20.2 0.1 4.7 7.6 0.0 3.9 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 CDO75275.1 - 0.017 13.2 0.0 0.022 12.8 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Ge1_WD40 PF16529.5 CDO75275.1 - 0.033 13.1 0.1 4 6.3 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 CDO75275.1 - 0.046 13.5 0.6 13 5.5 0.2 3.5 2 1 2 4 4 4 0 Lipoprotein LpqB beta-propeller domain GspH PF12019.8 CDO75275.1 - 0.09 13.2 0.6 8.6 6.8 0.0 3.4 1 1 1 3 3 3 0 Type II transport protein GspH WD40 PF00400.32 CDO75276.1 - 4.2e-15 55.9 15.4 1.9e-05 25.3 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat NACHT PF05729.12 CDO75276.1 - 4.9e-06 26.6 0.0 1.6e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 CDO75276.1 - 4.9e-06 26.8 0.2 1.5 9.2 0.1 3.8 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 CDO75276.1 - 1.7e-05 25.3 0.4 5e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CDO75276.1 - 0.0033 17.7 0.0 0.0075 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 CDO75276.1 - 0.093 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain PX PF00787.24 CDO75277.1 - 1.6e-26 92.5 0.0 2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.27 CDO75278.1 - 1.6e-27 95.2 2.8 9.9e-15 54.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 CDO75279.1 - 1.8e-30 104.5 36.5 0.00033 21.4 0.1 11.3 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75279.1 - 6.9e-10 39.1 2.5 0.016 15.5 0.1 6.8 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 CDO75279.1 - 1.1e-05 25.9 1.5 0.00015 22.2 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 CDO75279.1 - 2.5e-05 24.3 0.1 9.9e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 NACHT domain PD40 PF07676.12 CDO75279.1 - 0.00032 20.5 0.0 9.7 6.3 0.0 5.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 CDO75279.1 - 0.0009 17.9 0.1 0.31 9.5 0.0 3.4 2 2 2 4 4 4 2 Cytochrome D1 heme domain AAA_22 PF13401.6 CDO75279.1 - 0.0029 17.9 0.0 0.0069 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 CDO75279.1 - 0.016 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain PALB2_WD40 PF16756.5 CDO75279.1 - 0.55 9.1 4.9 0.7 8.8 0.7 2.8 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Proteasome_A_N PF10584.9 CDO75279.1 - 5.4 6.8 13.0 23 4.8 0.0 5.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Sugar_tr PF00083.24 CDO75280.1 - 1.4e-75 254.9 17.1 1.8e-75 254.5 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO75280.1 - 6.3e-28 97.7 42.5 3.1e-24 85.6 20.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.24 CDO75281.1 - 6.2e-44 150.2 0.0 1e-43 149.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 CDO75281.1 - 5.5e-41 140.4 0.0 1.9e-40 138.6 0.0 2.0 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CDO75281.1 - 6.9e-18 64.5 0.4 2.4e-17 62.8 0.4 2.0 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CDO75281.1 - 5e-15 56.3 0.0 1e-14 55.3 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain NOG1_N PF17835.1 CDO75282.1 - 3.8e-49 166.7 1.2 3.8e-49 166.7 1.2 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 CDO75282.1 - 1.9e-29 101.4 1.4 5.7e-29 99.9 1.4 1.9 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 CDO75282.1 - 4.8e-27 93.5 0.1 1e-26 92.4 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CDO75282.1 - 1.3e-17 63.9 0.0 3e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Cauli_VI PF01693.16 CDO75282.1 - 3.1e-15 56.2 1.2 6e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Caulimovirus viroplasmin RNase_H PF00075.24 CDO75282.1 - 4.8e-11 43.0 0.8 1.2e-07 32.0 0.0 2.8 1 1 1 2 2 2 2 RNase H FeoB_N PF02421.18 CDO75282.1 - 1.2e-09 37.9 0.0 2.4e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CDO75282.1 - 0.0044 17.0 0.0 0.83 9.5 0.0 2.9 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CDO75282.1 - 0.012 15.7 0.3 2.3 8.3 0.0 2.9 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.16 CDO75282.1 - 0.072 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Sushi_2 PF09014.10 CDO75282.1 - 0.16 11.9 0.1 0.42 10.5 0.1 1.7 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain ANAPC_CDC26 PF10471.9 CDO75282.1 - 4.8 8.1 7.3 7.6 7.5 0.0 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 RRM_1 PF00076.22 CDO75284.1 - 7.3e-58 192.3 0.0 7.4e-18 64.1 0.0 6.3 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDO75284.1 - 3.4e-11 43.1 0.1 0.0055 16.8 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif RRM_Rrp7 PF17799.1 CDO75284.1 - 0.0021 17.9 0.3 1.3 8.8 0.0 3.5 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 CDO75284.1 - 0.0076 16.2 0.0 22 5.1 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 CDO75284.1 - 0.039 14.2 7.5 7.1 6.8 0.0 5.7 4 2 2 6 6 6 0 Cytosolic domain of 10TM putative phosphate transporter Nop14 PF04147.12 CDO75284.1 - 0.28 9.4 27.9 0.76 7.9 27.9 1.7 1 0 0 1 1 1 0 Nop14-like family NTP_transf_2 PF01909.23 CDO75285.1 - 0.03 14.6 0.0 0.084 13.2 0.0 1.9 2 0 0 2 2 2 0 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.11 CDO75285.1 - 0.081 13.2 0.0 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain Paf67 PF10255.9 CDO75286.1 - 6.3e-165 549.1 0.0 1.1e-163 544.9 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_16 PF13432.6 CDO75286.1 - 0.007 17.0 0.1 6.8 7.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDO75286.1 - 0.11 12.7 0.0 0.79 10.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SSF PF00474.17 CDO75287.1 - 3.7e-14 52.4 40.9 4.7e-14 52.1 36.0 2.6 2 1 0 2 2 2 1 Sodium:solute symporter family DUF3592 PF12158.8 CDO75287.1 - 0.061 13.4 0.1 0.061 13.4 0.1 4.5 5 2 1 6 6 6 0 Protein of unknown function (DUF3592) Glyco_hydr_30_2 PF14587.6 CDO75288.1 - 3.1e-24 86.3 0.0 4.6e-23 82.4 0.0 2.0 1 1 1 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_cc PF11790.8 CDO75288.1 - 0.00027 20.6 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_59 PF02057.15 CDO75288.1 - 0.00051 19.4 0.0 0.0007 18.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30 PF02055.16 CDO75288.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 CDO75288.1 - 0.076 13.2 0.4 0.37 11.1 0.4 2.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain Curlin_rpt PF07012.12 CDO75288.1 - 0.079 13.0 1.0 0.17 12.0 0.1 2.0 2 0 0 2 2 2 0 Curlin associated repeat Ndr PF03096.14 CDO75289.1 - 0.23 10.1 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Ndr family DEAD PF00270.29 CDO75294.1 - 5.7e-16 58.8 0.0 1.2e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO75294.1 - 5.7e-12 46.0 0.0 1.5e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO75294.1 - 1.3e-05 25.2 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC_6 PF15288.6 CDO75294.1 - 0.0043 16.8 2.1 0.012 15.4 2.1 1.7 1 0 0 1 1 1 1 Zinc knuckle AhpC-TSA_2 PF13911.6 CDO75294.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Pkinase_fungal PF17667.1 CDO75295.1 - 7e-25 87.7 0.9 1.6e-13 50.2 0.2 3.0 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 CDO75295.1 - 0.0021 18.0 0.2 0.0053 16.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family ETC_C1_NDUFA4 PF04800.12 CDO75296.1 - 8.8e-35 118.8 0.2 1.3e-34 118.3 0.2 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region RSN1_7TM PF02714.15 CDO75297.1 - 3.7e-37 128.1 19.3 3.7e-37 128.1 19.3 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CDO75297.1 - 6.5e-22 78.6 0.0 3.2e-15 56.8 0.0 2.8 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CDO75297.1 - 1.1e-19 70.8 1.1 4.3e-19 68.8 1.1 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 CDO75297.1 - 0.024 14.8 0.4 0.064 13.4 0.4 1.6 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter Wzy_C PF04932.15 CDO75297.1 - 1.6 8.4 7.8 11 5.6 0.1 3.5 3 0 0 3 3 3 0 O-Antigen ligase GH131_N PF18271.1 CDO75298.1 - 2.5e-46 158.5 0.0 3.5e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 CDO75298.1 - 2.2e-11 43.5 8.1 2.2e-11 43.5 8.1 1.7 1 1 0 1 1 1 1 Fungal cellulose binding domain Polysacc_lyase PF14099.6 CDO75298.1 - 0.00032 20.6 0.1 0.0012 18.7 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide lyase RIBIOP_C PF04950.12 CDO75299.1 - 2.9e-93 312.5 0.0 2.9e-93 312.5 0.0 2.1 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CDO75299.1 - 4.7e-29 100.3 0.0 1.7e-28 98.5 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 CDO75299.1 - 5.2e-06 26.9 0.1 2.2e-05 24.9 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain GTP_EFTU PF00009.27 CDO75299.1 - 1.9e-05 24.3 0.0 0.0056 16.3 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CDO75299.1 - 9.6e-05 22.7 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CDO75299.1 - 0.00054 20.4 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 CDO75299.1 - 0.001 19.2 0.1 0.0041 17.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CDO75299.1 - 0.001 18.8 0.2 0.0028 17.4 0.2 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CDO75299.1 - 0.0011 19.6 2.1 0.0012 19.4 0.0 2.2 2 0 0 2 2 1 1 ABC transporter RNA_helicase PF00910.22 CDO75299.1 - 0.0012 19.2 0.0 0.003 17.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Rtf2 PF04641.12 CDO75299.1 - 0.0012 18.2 3.2 0.0012 18.2 3.2 3.4 3 0 0 3 3 3 1 Rtf2 RING-finger NACHT PF05729.12 CDO75299.1 - 0.0016 18.4 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 CDO75299.1 - 0.0025 17.0 0.0 0.0048 16.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 CDO75299.1 - 0.0088 16.1 0.1 0.036 14.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CDO75299.1 - 0.0098 16.1 0.0 0.0098 16.1 0.0 2.8 3 1 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 CDO75299.1 - 0.014 15.3 0.4 0.03 14.2 0.4 1.5 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 CDO75299.1 - 0.019 14.7 0.2 0.068 12.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 CDO75299.1 - 0.02 14.9 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 CDO75299.1 - 0.02 14.5 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CDO75299.1 - 0.021 14.5 0.1 0.021 14.5 0.1 2.4 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 CDO75299.1 - 0.026 14.8 0.7 0.055 13.7 0.0 1.9 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 CDO75299.1 - 0.027 14.4 0.1 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 CDO75299.1 - 0.031 14.2 0.1 0.28 11.1 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 CDO75299.1 - 0.036 14.6 0.0 0.036 14.6 0.0 2.6 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CDO75299.1 - 0.041 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 CDO75299.1 - 0.046 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 CDO75299.1 - 0.058 13.6 2.2 0.08 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDO75299.1 - 0.068 12.7 0.1 0.16 11.5 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CDO75299.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CDO75299.1 - 0.14 12.5 0.3 0.4 11.0 0.2 1.7 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 CDO75299.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATP_bind_1 PF03029.17 CDO75299.1 - 0.17 11.6 0.1 0.42 10.3 0.0 1.6 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 CDO75299.1 - 0.23 11.9 0.1 0.23 11.9 0.1 3.3 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 CDO75299.1 - 2.6 8.5 12.5 5.4 7.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CDO75299.1 - 7.2 6.6 7.6 2.1 8.4 0.0 3.4 4 0 0 4 4 3 0 Helicase HerA, central domain Cep57_MT_bd PF06657.13 CDO75300.1 - 1.1e-24 86.7 0.1 1.1e-24 86.7 0.1 4.1 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 CDO75300.1 - 3e-09 36.8 12.5 3e-09 36.8 12.5 4.1 2 2 1 3 3 3 1 Centrosome localisation domain of PPC89 IZUMO PF15005.6 CDO75300.1 - 1.8 9.0 4.9 2.3 8.7 3.4 1.9 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Pox_A_type_inc PF04508.12 CDO75300.1 - 8.5 6.4 16.2 0.89 9.5 2.4 4.1 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat ABC_membrane PF00664.23 CDO75301.1 - 8.2e-103 343.8 23.0 3.2e-52 177.9 10.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDO75301.1 - 4e-63 212.0 0.0 1.9e-32 112.7 0.0 3.8 3 0 0 3 3 3 3 ABC transporter SMC_N PF02463.19 CDO75301.1 - 3.1e-14 52.9 0.0 0.0002 20.9 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDO75301.1 - 9.8e-07 28.4 1.0 0.0026 17.4 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CDO75301.1 - 1.4e-06 28.3 0.0 0.036 13.8 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 CDO75301.1 - 4.8e-06 26.7 0.2 0.013 15.7 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CDO75301.1 - 3.3e-05 23.8 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 CDO75301.1 - 4.6e-05 23.4 0.4 0.34 10.7 0.1 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 CDO75301.1 - 4.7e-05 22.8 0.0 0.15 11.3 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 CDO75301.1 - 5.6e-05 23.4 4.4 0.1 12.8 0.2 4.1 4 1 0 4 4 2 2 AAA domain AAA_23 PF13476.6 CDO75301.1 - 5.6e-05 23.7 5.3 0.12 12.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CDO75301.1 - 0.00012 21.9 0.3 1.5 8.5 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 CDO75301.1 - 0.00027 20.6 0.1 0.095 12.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 CDO75301.1 - 0.00028 20.2 0.0 0.39 9.8 0.0 2.5 2 1 0 2 2 2 2 G-protein alpha subunit AAA PF00004.29 CDO75301.1 - 0.00096 19.6 0.8 16 5.9 0.1 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CDO75301.1 - 0.0012 18.4 0.0 0.98 8.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 CDO75301.1 - 0.0014 19.1 10.7 0.052 13.9 0.1 4.1 3 2 1 4 4 3 2 AAA ATPase domain AAA_28 PF13521.6 CDO75301.1 - 0.0026 18.0 0.1 0.94 9.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF2628 PF10947.8 CDO75301.1 - 0.0028 18.0 0.1 0.02 15.3 0.1 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2628) CDC45 PF02724.14 CDO75301.1 - 0.0068 14.8 0.0 0.051 11.9 0.1 2.0 2 0 0 2 2 2 1 CDC45-like protein AAA_5 PF07728.14 CDO75301.1 - 0.0072 16.3 0.2 4 7.4 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CDO75301.1 - 0.013 16.0 0.0 10 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CDO75301.1 - 0.019 15.1 0.1 14 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CDO75301.1 - 0.038 13.7 0.0 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 CDO75301.1 - 0.043 13.9 0.0 17 5.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 CDO75301.1 - 0.046 12.9 0.0 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 CDO75301.1 - 0.06 13.4 6.0 12 5.9 0.0 4.2 5 0 0 5 5 5 0 Helicase HerA, central domain RNA_helicase PF00910.22 CDO75301.1 - 0.062 13.7 0.1 7.3 7.0 0.0 3.1 3 0 0 3 3 2 0 RNA helicase DUF815 PF05673.13 CDO75301.1 - 0.089 11.9 0.0 9.8 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CDO75301.1 - 0.097 12.4 0.2 12 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 CDO75301.1 - 0.1 11.4 3.0 0.47 9.2 0.0 3.1 4 0 0 4 4 4 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.25 CDO75301.1 - 0.16 11.6 0.3 15 5.1 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 CDO75301.1 - 8.6 6.8 8.1 49 4.3 0.0 4.0 4 0 0 4 4 3 0 AAA domain HA2 PF04408.23 CDO75302.1 - 2e-22 79.5 0.1 5.6e-22 78.1 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CDO75302.1 - 1.6e-09 38.1 0.0 3.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CDO75302.1 - 2.2e-09 37.5 0.0 4.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 CDO75302.1 - 3.6e-06 27.3 0.0 7.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CDO75302.1 - 9.4e-06 25.5 0.3 3.6e-05 23.6 0.2 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CDO75302.1 - 0.0021 17.8 0.2 0.0049 16.6 0.2 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 CDO75302.1 - 0.019 14.4 0.0 0.055 12.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 CDO75302.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 CDO75302.1 - 0.032 14.6 0.1 0.072 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CDO75302.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CDO75302.1 - 0.097 12.2 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 CDO75302.1 - 0.14 12.1 0.0 3.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 CDO75302.1 - 0.2 12.1 0.0 0.39 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4203 PF13886.6 CDO75303.1 - 2.2e-06 27.5 19.2 4e-06 26.6 19.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Romo1 PF10247.9 CDO75303.1 - 4.7 7.6 6.9 6.2 7.3 0.1 2.6 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Nipped-B_C PF12830.7 CDO75304.1 - 3.7e-48 164.0 0.2 1.9e-47 161.7 0.2 2.4 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 CDO75304.1 - 2.8e-14 53.1 0.5 1.9e-13 50.4 0.2 2.6 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 CDO75304.1 - 0.00031 20.7 0.3 1.1 9.7 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 CDO75304.1 - 0.0017 18.7 3.9 0.017 15.5 0.1 4.0 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 CDO75304.1 - 0.056 14.0 0.8 49 4.6 0.0 4.9 4 0 0 4 4 4 0 HEAT-like repeat RsbU_N PF08673.10 CDO75304.1 - 0.066 13.3 0.1 0.21 11.7 0.1 1.9 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain UDPGT PF00201.18 CDO75308.1 - 2.6e-19 69.4 0.1 4e-19 68.8 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO75308.1 - 0.0002 21.4 0.3 0.00076 19.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain BRX_N PF13713.6 CDO75308.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain APG5 PF04106.12 CDO75309.1 - 3.5e-08 33.3 0.0 3.9e-08 33.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg5 FAM83 PF07894.12 CDO75309.1 - 0.045 13.3 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 FAM83 A-H RT_RNaseH PF17917.1 CDO75310.1 - 1.5e-37 128.0 0.0 2.5e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO75310.1 - 7.5e-35 119.0 0.0 1.4e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO75310.1 - 1.2e-27 96.8 0.0 2e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4809 PF16067.5 CDO75310.1 - 0.16 12.1 0.6 8.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4809) Sugar_tr PF00083.24 CDO75311.1 - 5.5e-114 381.5 14.8 6.4e-114 381.3 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO75311.1 - 1.9e-23 83.0 27.4 1.9e-23 83.0 27.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase_fungal PF17667.1 CDO75312.1 - 2.6e-41 141.8 0.0 1.8e-40 139.0 0.0 2.4 1 1 0 1 1 1 1 Fungal protein kinase Retrotran_gag_2 PF14223.6 CDO75313.1 - 2.8e-11 43.2 0.0 1.9e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 CDO75313.1 - 2.1e-10 40.8 0.1 3.9e-08 33.5 0.1 2.4 1 1 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO75313.1 - 5.6e-09 35.7 0.1 1.5e-08 34.4 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO75313.1 - 0.00023 20.9 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF4219 PF13961.6 CDO75313.1 - 1.7 8.4 6.0 11 5.8 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4219) Plavaka PF18759.1 CDO75314.1 - 1.5e-53 182.1 0.1 2e-53 181.8 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase Myb_DNA-bind_3 PF12776.7 CDO75315.1 - 7.8e-09 36.4 0.0 2.2e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain RsbRD_N PF14361.6 CDO75315.1 - 0.046 14.4 0.5 0.17 12.6 0.2 1.9 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Plavaka PF18759.1 CDO75316.1 - 2.1e-14 53.5 2.5 2.1e-14 53.5 2.5 1.9 2 1 0 2 2 2 1 Plavaka transposase GPAT_N PF14829.6 CDO75316.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Retrotran_gag_2 PF14223.6 CDO75317.1 - 9.2e-13 48.0 0.1 1.3e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4820 PF16091.5 CDO75317.1 - 0.048 13.0 1.4 0.086 12.2 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4219 PF13961.6 CDO75317.1 - 0.38 10.5 1.6 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) 40S_SA_C PF16122.5 CDO75317.1 - 9.4 7.7 11.1 10 7.6 9.2 1.9 2 0 0 2 2 2 0 40S ribosomal protein SA C-terminus Sad1_UNC PF07738.13 CDO75318.1 - 5.3e-18 65.3 0.0 3.1e-10 40.2 0.0 2.5 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal WD40 PF00400.32 CDO75320.1 - 6.8e-10 39.4 3.9 4.7e-05 24.1 0.0 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75320.1 - 3.2e-06 27.4 0.0 0.026 14.8 0.0 4.0 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO75320.1 - 0.0021 17.1 0.0 0.41 9.5 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Transposase_21 PF02992.14 CDO75322.1 - 3.2e-17 62.5 0.0 7.3e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 CDO75322.1 - 0.0062 16.1 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF4218 PF13960.6 CDO75322.1 - 0.033 13.8 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Integrase_H2C2 PF17921.1 CDO75323.1 - 1.7e-17 63.3 0.1 4.7e-17 61.8 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO75323.1 - 1e-14 54.8 0.0 1.7e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDO75323.1 - 3.9e-07 30.2 0.1 7.9e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger DNA_pol_E_B PF04042.16 CDO75324.1 - 7.8e-28 97.3 0.2 1.7e-27 96.1 0.2 1.6 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 CDO75324.1 - 1.2e-21 77.8 0.3 7.9e-12 45.7 0.1 2.2 1 1 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal Metallophos_3 PF14582.6 CDO75324.1 - 0.17 11.2 0.0 0.6 9.4 0.0 1.8 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Pkinase_fungal PF17667.1 CDO75325.1 - 3.2e-50 171.1 0.0 1.3e-49 169.1 0.0 2.0 1 1 0 1 1 1 1 Fungal protein kinase Macro_2 PF14519.6 CDO75326.1 - 0.00027 20.4 0.1 0.00083 18.8 0.1 1.7 1 1 0 1 1 1 1 Macro-like domain MerE PF05052.12 CDO75327.1 - 0.049 13.6 0.5 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 MerE protein Glyco_hydro_88 PF07470.13 CDO75328.1 - 4.9e-19 68.6 1.2 6.7e-19 68.2 1.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DASH_Dad1 PF08649.10 CDO75329.1 - 1.4e-23 82.8 1.5 1.8e-23 82.5 1.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 CDO75329.1 - 0.002 18.0 0.0 0.0025 17.7 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 Pkinase PF00069.25 CDO75330.1 - 2.9e-56 190.8 0.3 9.5e-49 166.1 0.0 2.7 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75330.1 - 4.3e-31 108.1 0.0 2.3e-27 95.9 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase C1_1 PF00130.22 CDO75330.1 - 3.3e-20 71.7 27.4 1e-11 44.5 10.3 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 CDO75330.1 - 2.2e-19 69.3 26.5 7.2e-14 51.7 5.0 3.0 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 CDO75330.1 - 2.6e-09 37.6 0.8 1e-08 35.7 0.3 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 CDO75330.1 - 0.041 13.2 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like C1_2 PF03107.16 CDO75330.1 - 6.2 7.2 21.7 2.9 8.3 8.1 2.4 2 0 0 2 2 2 0 C1 domain Endosulfine PF04667.17 CDO75332.1 - 7.4e-26 90.1 0.6 1e-25 89.7 0.5 1.4 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region LPD34 PF18852.1 CDO75333.1 - 0.13 11.9 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 Transposase_21 PF02992.14 CDO75335.1 - 4.6e-08 32.6 0.0 7.8e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4214 PF13946.6 CDO75335.1 - 0.093 12.8 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) DUF433 PF04255.14 CDO75336.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) EXS PF03124.14 CDO75340.1 - 1e-64 219.0 9.4 2.5e-28 99.3 1.1 3.0 2 1 1 3 3 3 3 EXS family DUF1003 PF06210.11 CDO75340.1 - 0.093 12.8 0.5 0.18 11.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) 2-Hacid_dh_C PF02826.19 CDO75341.1 - 4e-47 159.8 0.0 5.8e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CDO75341.1 - 2.5e-18 66.0 0.0 3.5e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CDO75341.1 - 2.1e-06 28.0 0.0 1e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DPBB_1 PF03330.18 CDO75342.1 - 0.00074 19.8 0.3 0.0026 18.0 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase Pro-kuma_activ PF09286.11 CDO75343.1 - 7.8e-27 94.3 0.0 9.5e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Bromodomain PF00439.25 CDO75344.1 - 9.9e-27 92.8 1.1 1.7e-26 92.1 0.2 1.9 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 CDO75344.1 - 1.2e-06 28.7 0.1 3.2e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CDO75344.1 - 9.8e-05 22.3 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDO75344.1 - 0.0039 17.6 0.3 0.0072 16.7 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CAF1A PF12253.8 CDO75344.1 - 0.015 15.5 0.3 0.032 14.4 0.3 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Pro_isomerase PF00160.21 CDO75345.1 - 2.3e-48 164.4 0.1 3.2e-48 164.0 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 CDO75345.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain DEAD PF00270.29 CDO75346.1 - 8.5e-40 136.4 0.0 1.6e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 CDO75346.1 - 6e-18 64.8 0.4 1.2e-17 63.9 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 CDO75346.1 - 4.7e-17 62.3 0.0 9.5e-16 58.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO75346.1 - 0.00044 20.3 0.0 0.00082 19.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit YL1 PF05764.13 CDO75346.1 - 0.00065 19.9 12.9 0.00065 19.9 12.9 3.2 3 0 0 3 3 3 1 YL1 nuclear protein SDA1 PF05285.12 CDO75346.1 - 0.0049 16.3 21.2 0.0049 16.3 21.2 2.7 3 0 0 3 3 3 1 SDA1 DNA_pol_phi PF04931.13 CDO75346.1 - 2.3 6.2 37.7 4.8 5.1 37.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 CDO75346.1 - 3.2 7.0 29.1 10 5.3 29.1 1.9 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 CDO75346.1 - 3.7 6.6 43.5 0.013 14.6 29.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 CDO75346.1 - 8.6 4.4 35.0 0.034 12.4 25.4 1.7 2 0 0 2 2 2 0 Nop14-like family MOZ_SAS PF01853.18 CDO75347.1 - 1e-81 272.9 0.4 1.5e-81 272.4 0.4 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CDO75347.1 - 1.9e-22 78.6 1.2 3.7e-22 77.7 1.2 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CDO75347.1 - 3e-18 65.5 0.0 7e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CDO75347.1 - 0.0025 18.2 0.0 0.0052 17.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO75347.1 - 0.0087 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HTH_Mga PF08280.11 CDO75347.1 - 0.012 15.6 0.5 0.03 14.3 0.5 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_11 PF08279.12 CDO75347.1 - 0.013 15.4 0.1 0.031 14.2 0.1 1.6 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.10 CDO75347.1 - 0.11 12.3 0.1 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain ORC6 PF05460.13 CDO75347.1 - 0.5 9.6 5.1 0.87 8.8 5.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) LAG1-DNAbind PF09271.11 CDO75348.1 - 2.4e-50 171.1 0.0 4.2e-50 170.3 0.0 1.4 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 CDO75348.1 - 5.3e-11 43.0 0.0 9.4e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain CAGE1 PF15066.6 CDO75350.1 - 0.0032 16.2 1.5 0.0056 15.4 1.5 1.3 1 0 0 1 1 1 1 Cancer-associated gene protein 1 family DUF724 PF05266.14 CDO75350.1 - 0.056 13.3 1.2 0.096 12.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Pkinase PF00069.25 CDO75351.1 - 7e-52 176.4 0.2 1.6e-51 175.2 0.2 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75351.1 - 3.2e-21 75.8 0.0 5.3e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO75351.1 - 6.3e-05 23.0 1.7 0.00019 21.4 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CDO75351.1 - 0.0016 18.0 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 CDO75351.1 - 0.07 12.7 0.4 0.14 11.7 0.4 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Put_Phosphatase PF06888.12 CDO75352.1 - 5e-45 153.7 0.1 5.7e-31 107.7 0.0 2.0 1 1 1 2 2 2 2 Putative Phosphatase HAD PF12710.7 CDO75352.1 - 4e-05 24.1 0.7 0.082 13.3 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 CDO75352.1 - 0.029 13.9 0.1 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) p450 PF00067.22 CDO75353.1 - 3.3e-65 220.6 0.6 1e-43 149.8 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 BSD PF03909.17 CDO75354.1 - 2.5e-20 72.2 0.1 1.2e-13 50.8 0.0 2.7 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 CDO75354.1 - 7.2e-15 55.1 0.0 1.4e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Semialdhyde_dh PF01118.24 CDO75354.1 - 0.014 15.9 0.1 0.54 10.7 0.0 3.3 5 0 0 5 5 5 0 Semialdehyde dehydrogenase, NAD binding domain GvpG PF05120.12 CDO75354.1 - 0.063 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Gas vesicle protein G CASP_C PF08172.12 CDO75355.1 - 3.4e-78 262.5 0.8 3.4e-78 262.5 0.8 4.8 3 2 1 4 4 4 1 CASP C terminal KLRAQ PF10205.9 CDO75355.1 - 0.0097 16.1 0.3 0.0097 16.1 0.3 5.6 5 1 0 5 5 5 1 Predicted coiled-coil domain-containing protein zf-CCCH_4 PF18044.1 CDO75355.1 - 0.22 11.4 0.1 0.35 10.7 0.1 1.2 1 0 0 1 1 1 0 CCCH-type zinc finger DUF1664 PF07889.12 CDO75355.1 - 0.76 9.8 33.2 1 9.4 0.1 5.2 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CDO75355.1 - 2.2 8.8 49.4 3.4 8.1 0.2 8.8 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) LPP PF04728.13 CDO75355.1 - 6.4 7.3 22.0 0.76 10.2 1.4 5.5 4 1 1 5 5 5 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 CDO75355.1 - 7.1 5.9 51.4 0.12 11.7 13.4 4.6 1 1 4 5 5 5 0 Domain of unknown function (DUF4407) Ribosomal_S9 PF00380.19 CDO75356.1 - 2.3e-42 144.4 0.5 1.6e-41 141.6 0.5 2.0 1 1 0 1 1 1 1 Ribosomal protein S9/S16 BRE1 PF08647.11 CDO75357.1 - 2.2e-18 66.1 11.8 2.2e-18 66.1 11.8 7.9 7 2 2 9 9 9 3 BRE1 E3 ubiquitin ligase Ribosomal_L29 PF00831.23 CDO75357.1 - 0.067 13.2 0.3 0.067 13.2 0.3 6.5 6 2 1 7 7 7 0 Ribosomal L29 protein zf-C3HC4_3 PF13920.6 CDO75357.1 - 0.13 12.2 3.8 0.23 11.3 3.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DASH_Duo1 PF08651.10 CDO75358.1 - 6.1e-22 77.2 1.0 1.1e-21 76.4 1.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF2367 PF10164.9 CDO75359.1 - 6.1e-07 29.9 2.9 1.1e-06 29.1 2.9 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Methyltransf_25 PF13649.6 CDO75360.1 - 1.8e-14 54.2 0.0 3.8e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO75360.1 - 4.6e-12 46.0 0.1 9e-12 45.0 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO75360.1 - 1.4e-11 44.9 0.0 2.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CDO75360.1 - 1.5e-11 44.2 0.0 2.2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 CDO75360.1 - 6.5e-08 32.6 0.0 2.8e-07 30.5 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO75360.1 - 1.3e-07 32.3 0.0 2.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CDO75360.1 - 2.4e-07 30.0 0.0 3.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 CDO75360.1 - 8.6e-07 28.5 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CDO75360.1 - 3.4e-06 26.7 0.2 5.7e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CDO75360.1 - 8.3e-05 22.5 0.1 0.00013 21.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDO75360.1 - 0.00023 20.6 0.1 0.00033 20.1 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 CDO75360.1 - 0.00046 19.7 1.9 0.0009 18.7 0.8 2.1 2 1 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 CDO75360.1 - 0.0027 17.7 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CDO75360.1 - 0.0027 17.5 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CDO75360.1 - 0.0027 17.5 0.1 0.0041 16.9 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 CDO75360.1 - 0.011 16.7 0.0 0.03 15.4 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain PRMT5 PF05185.16 CDO75360.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 CDO75360.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.20 CDO75360.1 - 0.073 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DOT1 PF08123.13 CDO75360.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 CDO75360.1 - 0.12 11.8 0.3 0.28 10.6 0.1 1.7 2 0 0 2 2 2 0 Putative methyltransferase UPF0020 PF01170.18 CDO75360.1 - 0.13 11.9 0.1 0.62 9.7 0.1 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 F-box-like PF12937.7 CDO75361.1 - 3.5e-05 23.6 0.0 0.00013 21.8 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO75361.1 - 0.042 13.8 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 F-box domain CDT1_C PF16679.5 CDO75361.1 - 0.1 13.1 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Tyrosinase PF00264.20 CDO75362.1 - 3.6e-16 60.1 0.9 4.3e-16 59.9 0.9 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DDE_Tnp_4 PF13359.6 CDO75364.1 - 8.7e-18 64.5 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO75364.1 - 2.6e-05 23.9 0.0 6.4e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO75364.1 - 0.0042 16.7 0.1 0.0072 16.0 0.1 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO75364.1 - 0.031 14.6 0.1 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 CDO75365.1 - 0.00013 22.8 0.1 0.00035 21.5 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO75365.1 - 0.001 19.4 0.4 0.0027 18.0 0.2 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Adap_comp_sub PF00928.21 CDO75366.1 - 5.8e-68 229.1 0.1 6.2e-54 183.1 0.0 2.2 1 1 1 2 2 2 2 Adaptor complexes medium subunit family HAT PF02184.16 CDO75366.1 - 1.8e-22 78.9 56.8 8.8e-08 32.0 2.6 13.0 14 0 0 14 14 13 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 CDO75366.1 - 6.1e-22 76.4 30.4 0.00089 19.9 0.1 11.9 7 3 6 13 13 12 5 Tetratricopeptide repeat TPR_2 PF07719.17 CDO75366.1 - 1e-13 50.2 0.9 0.082 13.1 0.0 8.0 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO75366.1 - 1.2e-12 48.1 3.8 0.19 12.2 0.0 7.9 8 1 1 9 9 9 4 Tetratricopeptide repeat Suf PF05843.14 CDO75366.1 - 3e-09 37.3 20.8 0.055 13.4 0.2 6.9 4 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 CDO75366.1 - 3.2e-09 36.5 0.2 0.0023 18.2 0.0 5.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDO75366.1 - 3.3e-07 30.0 2.2 19 5.8 0.0 7.4 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 CDO75366.1 - 6.3e-06 25.6 18.9 0.092 11.9 0.3 5.8 3 3 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CDO75366.1 - 3.4e-05 24.0 4.0 0.82 10.0 0.0 5.7 5 2 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO75366.1 - 4.3e-05 23.1 0.5 4.6 7.0 0.0 5.1 5 0 0 5 5 5 2 TPR repeat TPR_9 PF13371.6 CDO75366.1 - 7.4e-05 22.8 5.2 1.2 9.4 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CDO75366.1 - 0.0001 22.7 7.6 11 7.0 0.0 7.1 8 1 0 8 8 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 CDO75366.1 - 0.00028 20.6 0.0 5.4 7.0 0.0 5.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDO75366.1 - 0.0015 18.4 6.6 5.4 7.3 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDO75366.1 - 0.0019 18.8 0.1 0.0019 18.8 0.1 7.1 8 2 1 9 9 6 1 Tetratricopeptide repeat SNAP PF14938.6 CDO75366.1 - 0.002 17.6 9.6 0.0023 17.4 0.1 4.1 3 1 0 4 4 4 1 Soluble NSF attachment protein, SNAP DUF5622 PF18533.1 CDO75366.1 - 0.13 12.4 0.2 0.44 10.7 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5622) U3_assoc_6 PF08640.11 CDO75366.1 - 0.34 11.0 19.1 0.12 12.4 0.8 5.9 4 3 3 7 7 7 0 U3 small nucleolar RNA-associated protein 6 UQ_con PF00179.26 CDO75367.1 - 1.2e-44 151.3 0.0 1.5e-40 138.1 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CDO75367.1 - 0.00069 19.3 0.0 0.0012 18.5 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B Fer2 PF00111.27 CDO75369.1 - 2.1e-11 43.6 0.1 2.9e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Phage_T7_Capsid PF05396.11 CDO75370.1 - 0.05 14.0 0.0 0.081 13.3 0.0 1.5 1 0 0 1 1 1 0 Phage T7 capsid assembly protein Defensin_propep PF00879.18 CDO75370.1 - 1.1 9.6 4.1 10 6.5 0.1 2.9 3 0 0 3 3 3 0 Defensin propeptide Pkinase PF00069.25 CDO75371.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 CDO75371.1 - 0.00035 20.2 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CDO75371.1 - 0.00085 19.3 0.5 0.32 10.9 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CDO75371.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 CDO75371.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) FAD_SOX PF18371.1 CDO75371.1 - 0.092 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Pkinase_Tyr PF07714.17 CDO75371.1 - 0.093 12.0 0.0 0.25 10.6 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.6 CDO75371.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like fn3_2 PF16893.5 CDO75372.1 - 9.7e-37 125.0 0.5 2e-36 124.0 0.5 1.5 1 0 0 1 1 1 1 Fibronectin type III domain BRCT PF00533.26 CDO75372.1 - 1.3e-09 38.3 0.0 2.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDO75372.1 - 1.6e-06 28.0 0.1 1.6e-05 24.7 0.1 2.3 1 1 0 1 1 1 1 twin BRCT domain CHS5_N PF16892.5 CDO75372.1 - 3.2e-05 23.8 0.5 6.4e-05 22.8 0.5 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT_2 PF16589.5 CDO75372.1 - 0.00086 19.7 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 CDO75372.1 - 0.00098 19.4 0.1 0.0033 17.7 0.1 2.0 1 0 0 1 1 1 1 Fibronectin type III domain OCC1 PF15506.6 CDO75375.1 - 0.86 9.8 0.0 0.86 9.8 0.0 3.0 3 0 0 3 3 3 0 OCC1 family DUF1348 PF07080.11 CDO75376.1 - 5.8e-62 207.4 5.5 6.6e-62 207.2 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 CDO75376.1 - 9.4e-07 29.4 0.2 1.3e-06 29.0 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 CDO75376.1 - 0.0011 19.4 0.1 0.0015 18.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 CDO75376.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase RNase_H PF00075.24 CDO75377.1 - 0.01 16.0 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 0 RNase H Zn_clus PF00172.18 CDO75378.1 - 7.6e-09 35.6 8.5 1.5e-08 34.6 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CDO75378.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain ABC_tran_CTD PF16326.5 CDO75378.1 - 0.074 13.3 0.5 0.28 11.5 0.1 2.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain SNARE PF05739.19 CDO75379.1 - 1.8e-08 34.3 0.1 3.3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 SNARE domain GHBP PF12772.7 CDO75379.1 - 0.08 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Growth hormone receptor binding Mss4 PF04421.13 CDO75380.1 - 4.8e-15 55.5 0.0 8.9e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Mss4 protein Acetyltransf_10 PF13673.7 CDO75380.1 - 3.1e-06 27.2 0.0 5.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO75380.1 - 1.9e-05 24.9 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO75380.1 - 5.2e-05 23.6 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 CDO75381.1 - 2.3e-72 243.6 0.0 2.7e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75381.1 - 9.5e-34 116.8 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CDO75381.1 - 1.7e-14 54.2 1.8 3.3e-14 53.3 1.8 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CDO75381.1 - 1.8e-05 23.8 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDO75381.1 - 0.00066 19.1 0.0 0.0025 17.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CDO75381.1 - 0.0098 15.5 0.0 0.54 9.8 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDO75381.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO75381.1 - 0.11 12.5 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family RVT_1 PF00078.27 CDO75383.1 - 1.8e-17 63.6 0.1 2.3e-17 63.3 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF503 PF04456.12 CDO75383.1 - 0.072 12.9 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF503) Plavaka PF18759.1 CDO75384.1 - 2.5e-26 92.7 0.0 7.7e-26 91.1 0.0 1.8 1 1 0 1 1 1 1 Plavaka transposase Retrotrans_gag PF03732.17 CDO75384.1 - 1.7e-13 50.6 0.0 5.2e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO75384.1 - 9.5e-10 38.3 0.0 3e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotran_gag_2 PF14223.6 CDO75384.1 - 0.21 11.2 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type SMN PF06003.12 CDO75384.1 - 0.38 10.0 0.0 0.38 10.0 0.0 3.4 4 0 0 4 4 4 0 Survival motor neuron protein (SMN) RT_RNaseH_2 PF17919.1 CDO75385.1 - 1.8e-34 117.8 0.0 3.6e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO75385.1 - 2.6e-33 114.5 0.0 3.9e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO75385.1 - 3.8e-21 75.6 0.0 7.8e-21 74.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) UCR_14kD PF02271.16 CDO75385.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit F-box-like PF12937.7 CDO75386.1 - 0.00022 21.0 0.4 0.00022 21.0 0.4 2.0 2 0 0 2 2 2 1 F-box-like HET PF06985.11 CDO75387.1 - 1.1e-15 58.3 2.0 4.5e-12 46.5 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ABC_membrane PF00664.23 CDO75388.1 - 1.6e-18 67.4 1.6 1.6e-18 67.4 1.6 2.9 3 0 0 3 3 3 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDO75388.1 - 8.6e-15 55.5 0.4 3.7e-14 53.4 0.0 2.3 2 1 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 CDO75388.1 - 2.6e-07 31.3 1.8 0.00045 20.8 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CDO75388.1 - 1.4e-05 25.1 1.8 0.0089 15.9 0.2 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDO75388.1 - 3.8e-05 23.2 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDO75388.1 - 0.026 14.9 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 CDO75388.1 - 0.026 14.4 0.0 0.079 12.9 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 CDO75388.1 - 0.027 14.2 0.0 0.085 12.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 CDO75388.1 - 0.048 13.5 1.2 0.34 10.6 1.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CDO75388.1 - 0.3 10.7 1.3 0.81 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 CDO75388.1 - 0.31 9.6 0.9 10 4.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain RseC_MucC PF04246.12 CDO75388.1 - 0.45 10.5 0.0 0.45 10.5 0.0 2.6 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Snapin_Pallidin PF14712.6 CDO75388.1 - 1.1 9.7 4.0 0.61 10.5 1.1 1.9 2 0 0 2 2 2 0 Snapin/Pallidin ATP-synt_G PF04718.15 CDO75390.1 - 7.6e-18 65.2 0.1 1.9e-17 63.9 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Fic PF02661.18 CDO75391.1 - 4.6e-08 33.8 0.1 1.1e-07 32.6 0.1 1.7 1 0 0 1 1 1 1 Fic/DOC family dCMP_cyt_deam_1 PF00383.23 CDO75392.1 - 2.9e-13 49.5 0.2 3.8e-13 49.2 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CDO75392.1 - 1.2e-06 28.8 0.3 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CDO75392.1 - 0.045 13.4 1.2 0.6 9.7 0.0 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Pkinase PF00069.25 CDO75393.1 - 3.6e-57 193.7 0.0 1.9e-50 171.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75393.1 - 4.8e-21 75.2 0.0 1.3e-17 63.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CDO75393.1 - 0.03 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF2737 PF10930.8 CDO75393.1 - 0.047 13.3 0.5 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2737) APH PF01636.23 CDO75393.1 - 0.056 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FA_desaturase PF00487.24 CDO75394.1 - 1.5e-10 41.3 23.9 5.5e-08 33.0 5.2 2.9 1 1 2 3 3 3 2 Fatty acid desaturase DUF3474 PF11960.8 CDO75394.1 - 0.0026 18.0 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) SIR2 PF02146.17 CDO75396.1 - 4.4e-31 108.2 0.0 3.6e-16 59.6 0.0 2.9 3 0 0 3 3 3 2 Sir2 family TPP_enzyme_M PF00205.22 CDO75396.1 - 0.0046 16.7 0.2 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF364 PF04016.12 CDO75396.1 - 0.018 14.6 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 Putative heavy-metal chelation PNTB PF02233.16 CDO75396.1 - 0.033 13.1 0.2 0.42 9.5 0.1 2.0 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit SIR2 PF02146.17 CDO75397.1 - 4.5e-14 52.8 0.0 1.5e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Sir2 family APH PF01636.23 CDO75397.1 - 5.6e-12 46.1 0.0 1.2e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO75397.1 - 8.6e-06 25.5 0.0 7.7e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 CDO75397.1 - 0.00011 21.7 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain TPP_enzyme_M PF00205.22 CDO75397.1 - 0.0086 15.8 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Pkinase_Tyr PF07714.17 CDO75397.1 - 0.016 14.5 0.0 0.15 11.3 0.0 2.3 1 1 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.14 CDO75397.1 - 0.03 13.5 0.0 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase Dimer_Tnp_hAT PF05699.14 CDO75398.1 - 1.2e-17 63.4 0.0 2.2e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HET PF06985.11 CDO75401.1 - 1.3e-09 38.6 0.0 6.1e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RTC4 PF14474.6 CDO75402.1 - 1.1e-12 48.2 0.0 2.6e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 RTC4-like domain DUF3123 PF11321.8 CDO75402.1 - 0.27 11.9 0.9 0.5 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Transposase_21 PF02992.14 CDO75403.1 - 1.5e-11 43.9 0.0 2.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 CDO75403.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Fungal_trans PF04082.18 CDO75404.1 - 8.6e-08 31.5 0.1 1.5e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain W2 PF02020.18 CDO75405.1 - 1.2e-18 66.9 1.6 4.4e-18 65.2 0.0 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Recombinase PF07508.13 CDO75405.1 - 0.001 19.4 0.1 0.29 11.6 0.0 2.6 2 0 0 2 2 2 2 Recombinase TetR PF13972.6 CDO75405.1 - 0.12 12.1 0.3 0.64 9.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial transcriptional repressor Plk4_PB1 PF18190.1 CDO75406.1 - 1e-09 38.5 0.0 2.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 1 Plk4_PB2 PF18409.1 CDO75406.1 - 1.5e-05 25.6 0.0 0.00012 22.7 0.0 2.3 3 0 0 3 3 3 1 Polo-like Kinase 4 Polo Box 2 Pkinase PF00069.25 CDO75407.1 - 2.1e-08 33.9 0.0 6.3e-07 29.0 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75407.1 - 0.00017 20.9 0.1 0.00025 20.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO75407.1 - 0.0056 15.5 0.0 0.0073 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Homez PF11569.8 CDO75407.1 - 0.075 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez PP2C PF00481.21 CDO75408.1 - 7.5e-65 219.1 0.1 1.8e-52 178.5 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 CDO75408.1 - 0.0028 17.6 0.1 0.044 13.7 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Choline_transpo PF04515.12 CDO75409.1 - 2.5e-81 273.4 11.6 2.5e-81 273.4 11.6 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter Pkinase PF00069.25 CDO75410.1 - 1.4e-08 34.4 0.0 6.5e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 CDO75410.1 - 9.1e-06 24.7 0.0 1.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CDO75410.1 - 0.0003 20.2 0.1 0.0011 18.3 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO75410.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDO75411.1 - 2.2e-08 33.8 0.0 8e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75411.1 - 9.1e-06 25.1 0.0 1.2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO75411.1 - 0.013 14.4 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CDO75411.1 - 0.019 14.9 1.0 0.048 13.6 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family LZ3wCH PF18517.1 CDO75413.1 - 7.5e-10 38.8 0.2 1.9e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Snapin_Pallidin PF14712.6 CDO75413.1 - 0.0033 17.8 5.7 0.0048 17.3 5.7 1.2 1 0 0 1 1 1 1 Snapin/Pallidin DUF4515 PF14988.6 CDO75413.1 - 0.0053 16.6 2.5 0.0061 16.4 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) HMMR_N PF15905.5 CDO75413.1 - 0.0093 15.5 2.7 0.011 15.2 2.7 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal FemAB PF02388.16 CDO75413.1 - 0.0099 14.8 1.5 0.01 14.7 1.5 1.1 1 0 0 1 1 1 1 FemAB family ABC_tran_CTD PF16326.5 CDO75413.1 - 0.027 14.7 1.9 0.027 14.7 1.9 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain PCRF PF03462.18 CDO75413.1 - 0.028 14.3 0.6 0.032 14.1 0.6 1.2 1 0 0 1 1 1 0 PCRF domain IMD PF08397.11 CDO75413.1 - 0.03 13.7 1.2 0.044 13.1 1.2 1.4 1 1 0 1 1 1 0 IRSp53/MIM homology domain DUF4164 PF13747.6 CDO75413.1 - 0.032 14.5 6.7 0.051 13.8 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3811 PF11656.8 CDO75413.1 - 0.041 14.3 4.0 0.057 13.8 4.0 1.2 1 0 0 1 1 1 0 YjbD family (DUF3811) Med9 PF07544.13 CDO75413.1 - 0.055 13.6 3.6 0.09 12.9 3.6 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 LemA PF04011.12 CDO75413.1 - 0.15 11.9 3.5 0.19 11.6 3.4 1.3 1 1 0 1 1 1 0 LemA family Siah-Interact_N PF09032.11 CDO75413.1 - 0.15 12.3 3.1 0.26 11.6 3.1 1.4 1 1 0 1 1 1 0 Siah interacting protein, N terminal TMF_DNA_bd PF12329.8 CDO75413.1 - 0.29 11.2 4.6 0.35 10.9 3.9 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 CDO75413.1 - 0.39 11.2 9.3 0.5 10.9 9.0 1.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF2205 PF10224.9 CDO75413.1 - 0.78 9.8 5.2 1.5 8.9 5.2 1.5 1 1 0 1 1 1 0 Short coiled-coil protein FUSC PF04632.12 CDO75413.1 - 0.89 8.0 5.1 0.9 8.0 5.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Val_tRNA-synt_C PF10458.9 CDO75413.1 - 1.1 9.6 5.9 7.9 6.9 0.3 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DivIC PF04977.15 CDO75413.1 - 3.3 7.5 10.4 0.75 9.6 3.3 2.2 1 1 1 2 2 2 0 Septum formation initiator Mnd1 PF03962.15 CDO75414.1 - 2.3e-15 56.6 0.0 7.4e-15 55.0 0.1 1.7 2 0 0 2 2 2 1 Mnd1 HTH domain Pkinase_fungal PF17667.1 CDO75418.1 - 4.3e-28 98.2 0.0 5.8e-15 55.0 0.0 2.6 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 CDO75418.1 - 0.0055 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DNA_meth_N PF18284.1 CDO75418.1 - 0.057 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 DNA methylase N-terminal domain RICTOR_N PF14664.6 CDO75419.1 - 3e-82 276.6 1.3 1.9e-64 218.0 0.0 3.6 3 1 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 CDO75419.1 - 2.6e-38 130.0 0.0 1.1e-34 118.4 0.0 4.4 2 1 2 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 CDO75419.1 - 2.2e-37 127.7 0.0 5.5e-36 123.3 0.0 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 CDO75419.1 - 7.1e-33 112.7 0.3 2.2e-29 101.5 0.0 4.6 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 CDO75419.1 - 4e-10 39.7 2.5 1.1e-09 38.3 2.5 1.8 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.22 CDO75419.1 - 0.00059 19.9 0.0 0.14 12.5 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 CDO75419.1 - 0.0078 16.6 0.3 0.29 11.5 0.0 3.2 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 CDO75419.1 - 0.029 14.9 0.2 5.6 7.6 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat Uds1 PF15456.6 CDO75419.1 - 0.93 9.7 5.2 0.77 9.9 0.6 2.7 2 0 0 2 2 2 0 Up-regulated During Septation Oxidored_FMN PF00724.20 CDO75420.1 - 2.3e-62 211.3 0.0 8e-62 209.5 0.0 1.7 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2090 PF09863.9 CDO75420.1 - 0.086 11.9 0.0 0.25 10.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2090) F-box-like PF12937.7 CDO75421.1 - 0.005 16.7 0.1 0.014 15.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like Sod_Cu PF00080.20 CDO75422.1 - 1.4e-31 109.6 0.0 1.9e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) NMT_C PF02799.15 CDO75423.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Motile_Sperm PF00635.26 CDO75424.1 - 6.5e-27 93.5 0.2 1.2e-26 92.6 0.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.8 CDO75424.1 - 0.00027 21.1 0.2 0.001 19.3 0.0 2.0 2 1 0 2 2 2 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Spc42p PF11544.8 CDO75424.1 - 0.01 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Spindle pole body component Spc42p ASH PF15780.5 CDO75424.1 - 0.038 14.2 0.1 0.089 13.0 0.1 1.6 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Pkinase PF00069.25 CDO75425.1 - 7.3e-69 232.1 0.0 9.3e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75425.1 - 2.9e-30 105.4 0.0 3.9e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CDO75425.1 - 4.4e-11 43.3 1.2 4.4e-11 43.3 1.2 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CDO75425.1 - 2.7e-07 29.9 0.1 4.3e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CDO75425.1 - 0.00033 20.1 0.0 0.00069 19.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CDO75425.1 - 0.0062 16.2 0.0 0.96 9.0 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CDO75425.1 - 0.018 14.4 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO75425.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family G-patch PF01585.23 CDO75426.1 - 7e-07 29.0 0.0 2.6e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CDO75426.1 - 0.029 14.4 2.7 1.3 9.1 0.3 3.2 3 0 0 3 3 3 0 G-patch domain SIKE PF05769.11 CDO75427.1 - 0.007 16.3 16.7 0.21 11.5 9.5 2.7 2 1 0 2 2 2 2 SIKE family Nsp1_C PF05064.13 CDO75427.1 - 0.05 13.4 0.8 0.05 13.4 0.8 2.4 2 1 0 2 2 2 0 Nsp1-like C-terminal region Pox_Ag35 PF03286.14 CDO75427.1 - 0.15 11.8 4.8 0.36 10.6 4.8 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein F-box-like PF12937.7 CDO75428.1 - 1.1e-12 47.7 0.0 2.9e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like DASH_Spc19 PF08287.11 CDO75428.1 - 0.081 12.8 0.3 18 5.2 0.0 2.5 2 1 0 2 2 2 0 Spc19 LRR_4 PF12799.7 CDO75428.1 - 0.18 12.3 3.1 25 5.5 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Band_7 PF01145.25 CDO75429.1 - 1.3e-14 54.7 0.1 1.9e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family MutS_III PF05192.18 CDO75430.1 - 4.8e-24 85.6 0.0 8e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.21 CDO75430.1 - 0.021 14.8 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 MutS domain V MutS_IV PF05190.18 CDO75430.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 MutS family domain IV Exo_endo_phos_2 PF14529.6 CDO75431.1 - 4.5e-07 29.7 0.0 1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC_6 PF15288.6 CDO75431.1 - 0.063 13.1 1.9 0.17 11.8 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle HIP1_clath_bdg PF16515.5 CDO75431.1 - 0.16 12.6 5.0 0.25 12.0 3.4 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-CCHC_5 PF14787.6 CDO75431.1 - 0.23 11.2 2.9 0.5 10.1 2.9 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger THOC7 PF05615.13 CDO75431.1 - 0.67 10.2 4.3 0.41 10.9 1.7 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 FPP PF05911.11 CDO75431.1 - 1.3 7.1 3.7 0.85 7.7 0.7 1.8 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil T3SS_needle_E PF08988.10 CDO75431.1 - 2.7 8.2 5.8 24 5.2 0.1 3.8 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle DUF1664 PF07889.12 CDO75432.1 - 0.055 13.5 0.6 0.055 13.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 CDO75432.1 - 0.085 13.2 9.4 2.3 8.6 2.9 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 CDO75432.1 - 0.11 11.8 22.0 0.66 9.3 21.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CALCOCO1 PF07888.11 CDO75432.1 - 0.34 9.7 22.6 0.54 9.1 22.6 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3584 PF12128.8 CDO75432.1 - 0.42 8.1 22.0 0.57 7.6 22.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CCDC144C PF14915.6 CDO75432.1 - 1.7 7.7 22.5 0.96 8.5 12.3 3.1 1 1 1 3 3 3 0 CCDC144C protein coiled-coil region Fez1 PF06818.15 CDO75432.1 - 2.7 8.4 16.3 5 7.5 16.3 1.4 1 0 0 1 1 1 0 Fez1 Occludin_ELL PF07303.13 CDO75432.1 - 3.6 8.4 7.8 11 6.8 1.7 2.9 1 1 1 2 2 2 0 Occludin homology domain Spc7 PF08317.11 CDO75432.1 - 5.9 5.7 25.3 0.61 8.9 9.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2205 PF10224.9 CDO75432.1 - 6.3 6.9 8.8 0.3 11.1 0.8 2.7 1 1 2 3 3 3 0 Short coiled-coil protein DUF2959 PF11172.8 CDO75432.1 - 8 6.5 13.3 18 5.4 6.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2959) DUF724 PF05266.14 CDO75433.1 - 0.0076 16.1 0.5 2.8 7.7 0.2 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF724) BLOC1_2 PF10046.9 CDO75433.1 - 0.059 13.7 1.0 3.3 8.1 0.0 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DNA_topoisoIV PF00521.20 CDO75433.1 - 0.068 12.0 0.8 0.083 11.8 0.8 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Plasmid_RAQPRD PF09686.10 CDO75433.1 - 0.38 11.0 0.1 0.38 11.0 0.1 2.7 2 1 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) tRNA-synt_1 PF00133.22 CDO75434.1 - 8.6e-134 447.0 0.0 1.2e-133 446.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CDO75434.1 - 1.2e-14 53.9 0.1 4.7e-09 35.5 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CDO75434.1 - 3e-07 30.5 0.1 1e-06 28.8 0.1 2.0 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CDO75434.1 - 0.011 15.1 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Cyclin_N PF00134.23 CDO75435.1 - 4.2e-45 152.6 0.6 1e-44 151.4 0.4 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDO75435.1 - 4.8e-28 97.6 0.0 1.1e-27 96.4 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DDE_1 PF03184.19 CDO75435.1 - 0.015 15.0 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease ProRS-C_1 PF09180.11 CDO75436.1 - 2e-28 98.4 1.9 4.3e-28 97.3 1.9 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 CDO75436.1 - 8e-16 58.5 0.0 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 CDO75436.1 - 3.1e-14 53.1 0.0 6.7e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 CDO75436.1 - 1.3e-08 34.9 0.0 3.2e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain TraC_F_IV PF11130.8 CDO75436.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Oxysterol_BP PF01237.18 CDO75437.1 - 2.3e-43 148.5 0.6 7.5e-25 87.5 0.4 3.3 2 1 0 2 2 2 2 Oxysterol-binding protein PIGA PF08288.12 CDO75438.1 - 4.3e-38 129.8 0.3 1.2e-37 128.3 0.2 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CDO75438.1 - 8.9e-24 84.4 1.2 1.6e-23 83.6 1.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CDO75438.1 - 8.9e-22 77.4 0.0 1.4e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CDO75438.1 - 3.9e-21 75.9 0.0 8.3e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CDO75438.1 - 1.4e-10 41.9 0.4 2.8e-10 40.9 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CDO75438.1 - 0.00069 20.0 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Transp_cyt_pur PF02133.15 CDO75439.1 - 1e-31 110.2 38.3 2.4e-30 105.7 38.3 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Carboxyl_trans PF01039.22 CDO75440.1 - 1.8e-49 168.7 0.0 6.7e-48 163.5 0.0 2.1 2 0 0 2 2 2 2 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CDO75441.1 - 3.3e-47 160.7 0.0 5.3e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 CDO75441.1 - 1e-25 89.9 0.0 2.7e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 CDO75441.1 - 1.3e-11 45.0 0.0 4.2e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 CDO75441.1 - 2.9e-09 36.6 0.8 9.5e-09 35.0 0.6 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme RimK PF08443.11 CDO75441.1 - 0.00026 20.6 0.0 0.0037 16.9 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 CDO75441.1 - 0.00027 20.5 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CDO75441.1 - 0.012 15.6 0.0 0.044 13.8 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CDO75441.1 - 0.022 14.6 0.2 9.5 6.1 0.1 3.5 2 1 1 3 3 3 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 CDO75441.1 - 0.035 13.8 0.1 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon GCV_H PF01597.19 CDO75441.1 - 0.04 13.8 0.4 1.6 8.6 0.1 2.8 2 1 1 3 3 3 0 Glycine cleavage H-protein ATPgrasp_ST PF14397.6 CDO75441.1 - 0.071 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATP-grasp_2 PF08442.10 CDO75441.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain HlyD_3 PF13437.6 CDO75441.1 - 0.084 13.6 0.4 11 6.8 0.1 2.9 2 0 0 2 2 2 0 HlyD family secretion protein DER1 PF04511.15 CDO75442.1 - 2.7e-35 122.0 1.7 3.4e-35 121.7 1.7 1.0 1 0 0 1 1 1 1 Der1-like family Pribosyltran PF00156.27 CDO75443.1 - 4.8e-16 58.7 0.3 6.6e-16 58.2 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NinG PF05766.12 CDO75444.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein TSC22 PF01166.18 CDO75444.1 - 0.22 11.9 0.0 0.49 10.7 0.0 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Transposase_21 PF02992.14 CDO75446.1 - 5.2e-12 45.5 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 CDO75447.1 - 1e-26 93.9 0.0 3.7e-26 92.1 0.0 1.9 1 1 0 1 1 1 1 Plavaka transposase DDE_3 PF13358.6 CDO75448.1 - 8.7e-08 32.0 0.0 0.016 14.9 0.0 3.4 3 0 0 3 3 3 3 DDE superfamily endonuclease Syja_N PF02383.18 CDO75449.1 - 1.8e-79 267.4 0.0 2.7e-79 266.8 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain zf-C2H2 PF00096.26 CDO75450.1 - 2.4e-09 37.1 17.6 0.0055 17.1 3.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO75450.1 - 4.2e-05 24.0 18.6 0.048 14.5 2.1 3.7 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CDO75450.1 - 0.0047 17.2 1.0 0.011 15.9 1.0 1.6 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 CDO75450.1 - 0.012 16.0 3.5 0.012 16.0 3.5 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 CDO75450.1 - 0.024 14.6 0.5 0.024 14.6 0.5 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger Fer4_9 PF13187.6 CDO75450.1 - 0.036 14.2 0.8 0.082 13.1 0.8 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain zf-BED PF02892.15 CDO75450.1 - 0.098 12.7 4.8 0.63 10.1 0.8 2.4 1 1 1 2 2 2 0 BED zinc finger EPF PF17181.4 CDO75450.1 - 0.15 12.0 0.5 0.34 10.9 0.5 1.6 1 0 0 1 1 1 0 Epidermal patterning factor proteins zf-C2H2_jaz PF12171.8 CDO75450.1 - 0.24 11.7 6.2 14 6.1 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 CDO75450.1 - 0.89 9.8 3.9 2 8.7 3.9 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2HE PF16278.5 CDO75450.1 - 2.4 8.7 4.9 1.6 9.3 2.7 1.9 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger ATPase-cat_bd PF12156.8 CDO75450.1 - 8.9 7.1 6.0 0.87 10.4 0.8 2.0 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase Pyr_redox_2 PF07992.14 CDO75451.1 - 6.3e-67 225.9 5.9 6.3e-67 225.9 5.9 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CDO75451.1 - 1.8e-42 144.1 1.9 3.3e-42 143.2 0.5 2.3 2 1 1 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CDO75451.1 - 2.8e-22 79.1 6.4 1.3e-19 70.5 0.8 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDO75451.1 - 7.6e-12 45.0 4.4 2.8e-10 39.9 0.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 CDO75451.1 - 3e-11 43.3 13.4 1.5e-10 41.1 0.1 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CDO75451.1 - 2.4e-10 40.2 4.3 2.1e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO75451.1 - 1.1e-08 35.1 4.9 2.7e-05 24.3 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CDO75451.1 - 1.1e-07 31.4 0.4 0.0024 17.1 0.1 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 CDO75451.1 - 1.5e-07 30.5 12.8 0.00036 19.4 0.9 4.1 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 CDO75451.1 - 1.3e-06 27.8 1.9 1.3e-06 27.8 1.9 4.4 3 1 2 5 5 5 1 FAD binding domain AlaDh_PNT_C PF01262.21 CDO75451.1 - 2.7e-05 23.6 4.4 0.0095 15.3 0.2 3.0 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CDO75451.1 - 4.2e-05 23.3 16.3 0.087 12.4 0.1 4.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 CDO75451.1 - 0.00014 21.2 2.8 0.0037 16.5 0.0 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 CDO75451.1 - 0.00026 20.4 9.9 0.022 14.0 0.6 3.4 3 1 0 3 3 3 2 FAD binding domain THF_DHG_CYH_C PF02882.19 CDO75451.1 - 0.035 13.4 1.6 0.071 12.4 0.1 2.3 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.12 CDO75451.1 - 5.5 5.9 8.8 6.1 5.8 0.7 3.5 3 1 0 3 3 3 0 Lycopene cyclase protein Lon_C PF05362.13 CDO75452.1 - 1.4e-65 220.7 0.3 2.4e-65 219.9 0.3 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CDO75452.1 - 6.8e-23 81.5 0.0 1.6e-22 80.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CDO75452.1 - 5.7e-10 39.3 0.0 1.5e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 CDO75452.1 - 1.1e-06 28.7 0.0 3.2e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_2 PF07724.14 CDO75452.1 - 1.8e-05 24.9 0.0 7.5e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 CDO75452.1 - 4.3e-05 23.3 0.0 0.00015 21.6 0.0 2.0 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_33 PF13671.6 CDO75452.1 - 0.0014 18.8 0.1 0.032 14.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CDO75452.1 - 0.0026 18.2 0.1 0.0026 18.2 0.1 3.9 3 2 1 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.17 CDO75452.1 - 0.0028 17.4 0.0 0.0083 15.9 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 CDO75452.1 - 0.0095 15.7 0.0 0.054 13.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Allexi_40kDa PF05549.11 CDO75452.1 - 0.015 14.8 1.0 1.4 8.4 0.2 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein AAA_22 PF13401.6 CDO75452.1 - 0.022 15.0 3.9 0.32 11.3 0.1 3.7 3 1 0 3 3 3 0 AAA domain AAA_3 PF07726.11 CDO75452.1 - 0.037 13.9 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP-bdg_M PF16360.5 CDO75452.1 - 0.055 14.1 0.5 0.22 12.2 0.5 2.0 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region RNA_helicase PF00910.22 CDO75452.1 - 0.11 12.9 0.0 0.37 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 CDO75452.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain RXLR PF16810.5 CDO75452.1 - 0.2 12.1 1.4 0.52 10.7 1.4 1.6 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity AAA_11 PF13086.6 CDO75452.1 - 0.26 11.0 4.3 0.72 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Coiled-coil_56 PF09813.9 CDO75452.1 - 0.83 9.7 5.5 0.96 9.5 0.5 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 56 Tubulin_3 PF14881.6 CDO75453.1 - 1.6e-21 76.8 0.0 4.7e-10 39.4 0.1 2.3 1 1 1 2 2 2 2 Tubulin domain Misat_Tub_SegII PF10644.9 CDO75453.1 - 6.7e-16 58.7 0.8 1.6e-15 57.4 0.8 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain DUF89 PF01937.19 CDO75454.1 - 9.2e-96 320.9 0.1 4.1e-49 167.4 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function DUF89 DUF787 PF05619.11 CDO75454.1 - 0.035 13.3 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) RasGEF_N PF00618.20 CDO75454.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 RasGEF N-terminal motif VHS PF00790.19 CDO75455.1 - 5.7e-14 52.2 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 CDO75455.1 - 1.4e-09 38.1 1.4 3.5e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 GAT domain PRP38_assoc PF12871.7 CDO75455.1 - 0.016 15.8 27.8 0.016 15.8 27.8 5.1 4 2 0 4 4 4 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Glyco_hydro_3 PF00933.21 CDO75456.1 - 4.7e-84 282.5 0.3 7.3e-84 281.9 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain RRM_1 PF00076.22 CDO75457.1 - 1.9e-11 43.6 0.1 2.9e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT PF02985.22 CDO75458.1 - 2e-07 30.7 9.3 0.7 10.3 0.1 8.7 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 CDO75458.1 - 9.2e-06 26.0 10.0 8.7 6.8 0.0 7.5 6 3 1 7 7 7 1 HEAT repeats RTP1_C1 PF10363.9 CDO75458.1 - 0.0015 18.7 0.0 0.65 10.2 0.0 4.2 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CDO75458.1 - 0.0031 18.0 0.1 0.0031 18.0 0.1 8.2 10 1 1 11 11 11 1 HEAT-like repeat Arm PF00514.23 CDO75458.1 - 0.0058 16.6 0.0 0.069 13.2 0.0 3.0 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat UME PF08064.13 CDO75458.1 - 0.006 16.5 2.3 4.2 7.3 0.2 5.2 4 1 1 5 5 5 1 UME (NUC010) domain TctA PF01970.16 CDO75458.1 - 0.016 14.0 0.5 0.45 9.2 0.1 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family Cnd3 PF12719.7 CDO75458.1 - 0.019 14.2 0.5 3.6 6.7 0.1 3.6 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain SMBP PF16785.5 CDO75458.1 - 0.14 12.4 2.6 0.39 10.9 0.9 2.5 2 0 0 2 2 2 0 Small metal-binding protein V-ATPase_H_C PF11698.8 CDO75458.1 - 0.14 12.2 0.0 5.3 7.2 0.0 3.1 2 0 0 2 2 2 0 V-ATPase subunit H PAP_assoc PF03828.19 CDO75459.1 - 1.4e-16 60.5 0.1 2.5e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CDO75459.1 - 6.4e-05 23.2 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CDO75459.1 - 0.037 14.1 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase stn_TNFRSF12A PF12191.8 CDO75459.1 - 8.2 6.7 5.9 0.73 10.1 0.1 2.3 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain GEN1_C PF18380.1 CDO75460.1 - 6e-29 101.0 0.0 6e-29 101.0 0.0 3.1 3 1 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 CDO75460.1 - 4.4e-21 75.1 0.0 9.6e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDO75460.1 - 7.4e-05 23.2 0.0 0.0002 21.8 0.0 1.7 1 1 0 1 1 1 1 XPG N-terminal domain RsdA_SigD_bd PF16751.5 CDO75460.1 - 0.077 13.3 0.2 0.19 12.0 0.2 1.7 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region Rap_GAP PF02145.15 CDO75461.1 - 5.5e-42 143.4 0.0 9.2e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 CDO75461.1 - 4.4e-36 124.7 0.7 1.8e-33 116.2 0.2 2.4 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.8 CDO75461.1 - 8.6e-08 31.5 0.5 0.00078 18.5 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3384) Cluap1 PF10234.9 CDO75462.1 - 0.016 14.6 4.3 0.02 14.3 4.3 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4200 PF13863.6 CDO75462.1 - 0.024 15.0 2.1 0.024 15.0 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 CDO75462.1 - 0.13 11.1 6.6 0.16 10.9 6.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein WXG100 PF06013.12 CDO75462.1 - 0.25 11.6 5.1 5 7.4 0.3 2.4 1 1 1 2 2 2 0 Proteins of 100 residues with WXG FliJ PF02050.16 CDO75462.1 - 3 8.1 15.3 14 6.0 13.1 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein SUI1 PF01253.22 CDO75463.1 - 8.6e-10 39.0 0.0 1.8e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Gas_vesicle_C PF01304.17 CDO75463.1 - 2.4 8.2 4.8 11 6.1 1.4 2.4 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain RNase_H PF00075.24 CDO75464.1 - 2.6e-06 27.7 0.0 3.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO75464.1 - 0.00028 21.5 0.0 0.00055 20.6 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GOLD_2 PF13897.6 CDO75465.1 - 0.41 11.1 2.1 1.7 9.1 0.1 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Plavaka PF18759.1 CDO75466.1 - 1.3e-20 73.9 0.0 2.2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase SBP_bac_10 PF07596.11 CDO75467.1 - 0.046 13.7 3.5 0.076 13.0 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1559) Plavaka PF18759.1 CDO75468.1 - 1.3e-127 425.6 0.0 2.1e-127 424.8 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 CDO75468.1 - 3.4 7.0 11.1 5 6.4 11.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CDO75468.1 - 5.2 5.2 9.5 7.3 4.7 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 CDO75468.1 - 5.6 4.9 12.4 8.4 4.4 12.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi DEAD PF00270.29 CDO75469.1 - 1.4e-15 57.5 0.0 2.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO75469.1 - 6.8e-15 55.4 0.0 1.9e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CDO75469.1 - 3.2e-07 31.0 0.2 7.6e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 RecQ zinc-binding NAD_binding_6 PF08030.12 CDO75470.1 - 7.6e-26 91.1 0.0 1.4e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CDO75470.1 - 8.9e-21 74.0 0.0 1.7e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CDO75470.1 - 1.2e-17 64.2 13.9 2.3e-17 63.3 13.9 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 CDO75470.1 - 0.00091 19.9 0.0 0.024 15.3 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain 2TM PF13239.6 CDO75470.1 - 2 8.8 11.5 7.2 7.0 0.1 3.7 2 1 1 3 3 3 0 2TM domain HORMA PF02301.18 CDO75471.1 - 5.5e-16 58.8 0.0 9.2e-16 58.1 0.0 1.4 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 CDO75471.1 - 0.00099 19.1 0.1 0.007 16.4 0.1 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 ATG13 PF10033.9 CDO75471.1 - 0.035 13.8 0.1 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Autophagy-related protein 13 Ribonucleas_3_3 PF14622.6 CDO75472.1 - 6.6e-08 32.8 0.0 4.2e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CDO75472.1 - 1.4e-06 28.8 0.0 4.6e-05 24.0 0.0 2.6 1 1 0 1 1 1 1 Ribonuclease III domain CAF1A PF12253.8 CDO75472.1 - 0.14 12.3 1.1 1.5 9.0 0.2 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A SKN1 PF03935.15 CDO75475.1 - 5.2e-193 642.0 0.2 6.1e-193 641.8 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 CDO75476.1 - 3.4e-189 629.4 0.7 3.9e-189 629.2 0.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) RSN1_7TM PF02714.15 CDO75477.1 - 8.2e-09 35.2 20.2 1.8e-08 34.0 20.2 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CDO75477.1 - 0.00058 19.7 0.2 0.00058 19.7 0.2 3.3 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 CDO75477.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter Sec1 PF00995.23 CDO75478.1 - 5.5e-126 422.1 0.0 6.9e-126 421.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Qua1 PF16274.5 CDO75478.1 - 0.41 10.5 1.2 0.73 9.7 0.1 2.0 2 0 0 2 2 2 0 Qua1 domain Bax1-I PF01027.20 CDO75479.1 - 2.2e-39 135.5 6.9 2.2e-39 135.5 6.9 1.5 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.32 CDO75480.1 - 4e-37 125.6 19.8 1.6e-06 28.7 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75480.1 - 2.1e-17 63.2 0.5 0.0028 17.9 0.0 6.2 1 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO75480.1 - 5.2e-07 28.9 0.1 0.076 12.0 0.0 3.4 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 CDO75480.1 - 5.1e-05 23.1 0.0 8.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 CDO75480.1 - 8.9e-05 22.5 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 CDO75480.1 - 0.0021 17.4 0.1 0.65 9.3 0.0 2.9 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CDO75480.1 - 0.0072 15.0 0.9 0.12 11.0 0.0 2.6 3 0 0 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.12 CDO75480.1 - 0.024 14.6 4.2 9.6 6.3 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 CDO75480.1 - 0.12 10.9 0.0 0.28 9.7 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40 PF00400.32 CDO75481.1 - 1.3e-05 25.8 5.4 0.17 12.8 0.1 4.6 3 1 0 3 3 3 2 WD domain, G-beta repeat RicinB_lectin_2 PF14200.6 CDO75481.1 - 0.00091 19.9 0.0 0.013 16.2 0.0 2.8 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Arginase PF00491.21 CDO75482.1 - 1.4e-87 293.8 0.1 1.9e-87 293.3 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 CDO75482.1 - 0.094 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain SUR7 PF06687.12 CDO75483.1 - 9.5e-18 64.6 13.4 1.4e-17 64.1 13.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Acetyltransf_3 PF13302.7 CDO75484.1 - 0.0028 18.3 0.1 0.0033 18.1 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CDO75485.1 - 1.3e-19 71.2 0.0 1.8e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CDO75485.1 - 4.9e-07 29.5 0.1 2.3e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO75485.1 - 5.7e-07 29.8 0.0 9.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO75485.1 - 0.07 13.6 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GTP_EFTU PF00009.27 CDO75486.1 - 3.1e-67 225.9 0.4 4.4e-67 225.4 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDO75486.1 - 1.3e-34 118.5 0.0 1e-33 115.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CDO75486.1 - 2.8e-21 75.4 0.0 6.1e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CDO75486.1 - 2.2e-13 50.1 0.0 5.7e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CDO75486.1 - 3.5e-13 49.7 0.0 1.3e-12 47.9 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDO75486.1 - 9e-05 22.5 0.3 0.0002 21.4 0.3 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PI-PLC-C1 PF16670.5 CDO75487.1 - 0.034 13.2 0.3 0.96 8.5 0.0 2.4 1 1 1 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent Utp11 PF03998.13 CDO75489.1 - 9.5e-74 248.4 31.2 1.2e-73 248.1 31.2 1.1 1 0 0 1 1 1 1 Utp11 protein Bac_luciferase PF00296.20 CDO75489.1 - 0.23 10.9 4.8 0.082 12.3 2.3 1.5 2 0 0 2 2 2 0 Luciferase-like monooxygenase VHS PF00790.19 CDO75490.1 - 1.4e-19 70.4 0.0 2.9e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 CDO75490.1 - 7.6e-07 29.4 1.4 2e-06 28.0 1.4 1.8 1 0 0 1 1 1 1 GAT domain RR_TM4-6 PF06459.12 CDO75490.1 - 0.12 12.1 12.6 0.3 10.9 12.6 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.16 CDO75490.1 - 0.39 10.0 9.4 0.68 9.3 9.4 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MAS20 PF02064.15 CDO75490.1 - 0.41 10.7 11.8 1.1 9.3 11.8 1.7 1 0 0 1 1 1 0 MAS20 protein import receptor Cnd1_N PF12922.7 CDO75490.1 - 0.99 9.2 3.9 2.2 8.1 3.9 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term ALMT PF11744.8 CDO75490.1 - 1.1 7.9 7.7 1.6 7.5 7.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Gemini_coat PF00844.18 CDO75490.1 - 2.9 7.3 5.8 5.4 6.4 5.8 1.3 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family DUF4778 PF16008.5 CDO75490.1 - 4.5 7.2 12.6 7.7 6.5 12.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) TT_ORF1 PF02956.14 CDO75490.1 - 5.5 5.5 9.0 8.7 4.9 9.0 1.2 1 0 0 1 1 1 0 TT viral orf 1 p450 PF00067.22 CDO75491.1 - 2e-24 86.2 0.0 3.1e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2b PF00587.25 CDO75491.1 - 6.3e-09 36.1 0.0 7.3e-08 32.6 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CDO75491.1 - 9.1e-07 29.1 0.5 1.7e-06 28.2 0.5 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DNA_pol3_delta2 PF13177.6 CDO75492.1 - 7.1e-13 48.7 0.1 4.6e-10 39.5 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CDO75492.1 - 1.1e-11 45.0 0.2 2.9e-11 43.6 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 CDO75492.1 - 1.7e-11 44.7 0.1 2.9e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDO75492.1 - 3.5e-07 30.7 0.0 3.8e-05 24.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CDO75492.1 - 4.1e-07 30.1 0.0 7.7e-07 29.2 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 CDO75492.1 - 1.6e-06 28.4 0.0 0.0022 18.3 0.0 2.4 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 CDO75492.1 - 6.4e-06 26.0 0.0 1.7e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 CDO75492.1 - 2.5e-05 24.2 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CDO75492.1 - 7e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CDO75492.1 - 0.00016 21.6 0.0 0.00042 20.3 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 CDO75492.1 - 0.00058 19.3 0.0 0.0086 15.5 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 CDO75492.1 - 0.0018 17.3 0.0 0.0045 16.0 0.0 1.6 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DNA_pol3_delta PF06144.13 CDO75492.1 - 0.0032 17.3 0.1 0.0046 16.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 CDO75492.1 - 0.0041 17.4 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain NTPase_1 PF03266.15 CDO75492.1 - 0.0045 16.9 0.2 0.018 15.0 0.1 1.9 1 1 1 2 2 2 1 NTPase AAA_11 PF13086.6 CDO75492.1 - 0.0055 16.5 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CDO75492.1 - 0.0096 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CDO75492.1 - 0.021 14.3 0.0 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 CDO75492.1 - 0.035 14.5 0.2 0.13 12.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CDO75492.1 - 0.059 13.9 0.1 0.16 12.6 0.1 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CDO75492.1 - 0.075 13.4 0.1 0.25 11.7 0.1 2.1 1 1 0 1 1 1 0 RNA helicase SRP54 PF00448.22 CDO75492.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 CDO75492.1 - 0.12 12.9 0.1 0.28 11.7 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DEAD PF00270.29 CDO75492.1 - 0.13 12.0 0.1 2.9 7.6 0.0 2.7 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 CDO75492.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 CDO75492.1 - 0.15 11.7 0.1 0.42 10.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain ParA PF10609.9 CDO75493.1 - 4.7e-88 294.8 0.0 5.9e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CDO75493.1 - 4e-07 30.1 0.0 8e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CDO75493.1 - 1.4e-05 24.5 0.4 0.0011 18.2 0.2 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 CDO75493.1 - 3e-05 24.0 0.1 0.0061 16.5 0.1 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 CDO75493.1 - 5.8e-05 22.5 0.0 0.00031 20.1 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 CDO75493.1 - 0.07 12.6 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 CDO75493.1 - 0.11 12.8 0.3 0.41 11.0 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.22 CDO75497.1 - 6e-09 35.6 0.0 0.0038 17.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDO75497.1 - 0.023 14.8 0.0 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif RNA_pol_Rpb6 PF01192.22 CDO75498.1 - 7.6e-15 54.6 0.1 1.1e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 SIR2 PF02146.17 CDO75499.1 - 9.3e-27 94.1 0.0 2.2e-24 86.4 0.0 2.2 1 1 0 1 1 1 1 Sir2 family Methyltransf_12 PF08242.12 CDO75500.1 - 0.022 15.5 0.0 0.07 13.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Ribonuclease_T2 PF00445.18 CDO75501.1 - 9.5e-32 110.7 0.0 1.3e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Myb_DNA-bind_7 PF15963.5 CDO75502.1 - 7.6e-23 80.2 0.1 2e-22 78.9 0.1 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CDO75502.1 - 1.3e-08 34.9 0.0 3.5e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CDO75502.1 - 0.0017 18.5 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SAA PF00277.18 CDO75502.1 - 0.035 14.6 2.7 0.083 13.4 2.7 1.6 1 0 0 1 1 1 0 Serum amyloid A protein CCDC71L PF15374.6 CDO75502.1 - 1.2 8.4 10.4 0.12 11.7 3.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L Herpes_UL6 PF01763.16 CDO75503.1 - 0.093 11.2 0.4 0.17 10.4 0.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Nup88 PF10168.9 CDO75503.1 - 0.13 10.0 0.3 0.22 9.3 0.3 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF1357 PF07094.11 CDO75503.1 - 0.28 11.2 0.1 0.28 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1357) TSNAXIP1_N PF15739.5 CDO75503.1 - 0.88 10.0 4.4 13 6.2 0.0 3.4 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus LUC7 PF03194.15 CDO75503.1 - 1.3 8.6 6.6 0.073 12.7 0.5 1.8 2 0 0 2 2 2 0 LUC7 N_terminus SURF1 PF02104.15 CDO75504.1 - 5.8e-44 150.4 0.2 7.1e-44 150.1 0.2 1.0 1 0 0 1 1 1 1 SURF1 family ANTH PF07651.16 CDO75505.1 - 5e-72 242.2 0.0 5e-72 242.2 0.0 3.5 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 CDO75505.1 - 2.1e-54 183.9 10.0 2.1e-54 183.9 10.0 5.0 2 1 2 5 5 5 1 I/LWEQ domain FAA_hydro_N_2 PF18288.1 CDO75505.1 - 7.3 7.1 11.6 0.29 11.6 1.4 3.5 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 SIR2 PF02146.17 CDO75507.1 - 1.4e-12 47.9 0.0 8.7e-08 32.3 0.0 2.4 2 1 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 CDO75507.1 - 0.024 14.4 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.16 CDO75507.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit DUF1192 PF06698.11 CDO75507.1 - 0.079 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Ion_trans PF00520.31 CDO75508.1 - 0.00012 21.4 4.7 0.00016 21.0 4.7 1.1 1 0 0 1 1 1 1 Ion transport protein CWC25 PF12542.8 CDO75509.1 - 1.9e-24 86.5 0.8 1.9e-24 86.5 0.8 4.0 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 CDO75509.1 - 4.5e-14 52.3 12.9 4.5e-14 52.3 12.9 5.1 3 3 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR MFS_1 PF07690.16 CDO75510.1 - 7.2e-46 156.7 34.3 1.2e-43 149.4 18.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO75510.1 - 2.7e-10 39.7 3.7 2.7e-10 39.7 3.7 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CDO75510.1 - 1.4e-06 27.0 4.3 1.4e-06 27.0 4.3 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 CDO75510.1 - 0.0023 16.8 4.1 0.0026 16.7 0.5 2.3 1 1 1 2 2 2 1 MFS_1 like family DUF515 PF04415.12 CDO75510.1 - 0.55 8.6 7.8 0.8 8.0 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MFS_2 PF13347.6 CDO75510.1 - 1.1 7.7 20.5 0.0064 15.1 5.9 2.8 2 1 1 3 3 3 0 MFS/sugar transport protein Fungal_trans PF04082.18 CDO75511.1 - 1.9e-26 92.7 0.0 6.8e-26 90.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CDO75511.1 - 1.6e-06 28.1 10.4 3e-06 27.2 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUKH-4 PF14435.6 CDO75511.1 - 0.059 13.4 3.1 0.064 13.3 0.3 2.4 2 0 0 2 2 2 0 SUKH-4 immunity protein DEC-1_N PF04625.13 CDO75512.1 - 0.0037 16.3 0.1 0.0045 16.1 0.1 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region PX PF00787.24 CDO75513.1 - 1.4e-21 76.6 0.4 1.1e-20 73.8 0.5 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CDO75513.1 - 0.0005 19.7 6.7 0.00092 18.8 4.5 2.3 2 1 0 2 2 2 1 Vps5 C terminal like BAR_3 PF16746.5 CDO75513.1 - 0.021 14.6 0.8 0.044 13.5 0.1 1.9 2 0 0 2 2 2 0 BAR domain of APPL family Lung_7-TM_R PF06814.13 CDO75514.1 - 6.9e-50 170.0 12.8 9.3e-50 169.5 12.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SafA PF17073.5 CDO75514.1 - 0.23 11.4 1.2 0.42 10.6 0.5 1.8 2 0 0 2 2 2 0 Two-component-system connector protein DUF2070 PF09843.9 CDO75514.1 - 6.4 4.9 13.5 9.1 4.4 13.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RNA_pol_Rpb2_6 PF00562.28 CDO75515.1 - 6.1e-128 427.2 0.2 8.4e-128 426.7 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CDO75515.1 - 6.6e-69 231.5 0.0 9.6e-69 231.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CDO75515.1 - 8.5e-48 162.5 0.1 1.8e-47 161.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CDO75515.1 - 8.8e-33 112.6 0.1 2e-32 111.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CDO75515.1 - 3.1e-26 91.4 0.4 8.5e-26 90.0 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CDO75515.1 - 3.4e-25 88.0 0.2 9.2e-25 86.6 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CDO75515.1 - 7.3e-24 84.1 0.5 2.2e-23 82.5 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 CDO75515.1 - 0.36 11.6 1.5 0.47 11.2 0.1 1.8 2 0 0 2 2 2 0 MRN-interacting protein Glyco_hydro_7 PF00840.20 CDO75516.1 - 2.3e-209 695.5 16.4 2.6e-209 695.3 16.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fructosamin_kin PF03881.14 CDO75517.1 - 1.6e-54 185.1 0.0 2e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 CDO75517.1 - 5.6e-06 26.5 0.0 6.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CDO75517.1 - 0.19 10.5 0.5 2.3 7.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) Oxidored_FMN PF00724.20 CDO75518.1 - 1.5e-61 208.5 0.0 2.1e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RAMPs PF03787.15 CDO75518.1 - 0.026 14.6 0.0 0.078 13.0 0.0 1.7 2 0 0 2 2 2 0 RAMP superfamily EF-hand_6 PF13405.6 CDO75521.1 - 0.073 13.0 0.0 0.37 10.8 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain Fe-ADH PF00465.19 CDO75522.1 - 2.2e-17 62.9 0.3 2.8e-17 62.6 0.3 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CDO75522.1 - 0.00031 20.5 0.1 0.00052 19.8 0.1 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase VPS13 PF16908.5 CDO75523.1 - 8.8e-07 28.9 0.6 1.8e-06 27.9 0.6 1.5 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal EF-hand_6 PF13405.6 CDO75523.1 - 0.039 13.9 0.3 0.4 10.7 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain DUF2318 PF10080.9 CDO75523.1 - 4.2 7.5 7.4 0.22 11.6 0.2 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Fe-ADH PF00465.19 CDO75524.1 - 8.1e-67 225.6 0.0 1e-66 225.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CDO75524.1 - 7.3e-14 52.1 0.0 1.3e-13 51.2 0.0 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Lactamase_B PF00753.27 CDO75525.1 - 5.1e-10 39.7 4.6 9.6e-10 38.8 4.6 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDO75525.1 - 0.0029 17.2 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HCMV_UL139 PF12507.8 CDO75528.1 - 0.014 15.7 1.2 0.05 14.0 0.1 2.0 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Med14 PF08638.11 CDO75529.1 - 2.4e-62 209.8 0.9 3.4e-62 209.3 0.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit MED14 HEAT PF02985.22 CDO75531.1 - 0.00011 22.2 0.1 4.6 7.8 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Pkinase PF00069.25 CDO75531.1 - 0.00028 20.3 0.0 0.00082 18.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain HEAT_EZ PF13513.6 CDO75531.1 - 0.01 16.3 0.3 14 6.3 0.1 3.9 3 0 0 3 3 3 0 HEAT-like repeat Cnd1 PF12717.7 CDO75531.1 - 0.012 15.7 0.0 1 9.4 0.0 3.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDO75531.1 - 0.068 13.6 0.2 3.8 8.0 0.0 3.6 4 0 0 4 4 4 0 HEAT repeats Pkinase_Tyr PF07714.17 CDO75531.1 - 0.07 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Zn_clus PF00172.18 CDO75532.1 - 0.057 13.6 2.0 0.088 12.9 2.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 CDO75535.1 - 1.9e-48 165.1 0.0 4.5e-43 147.4 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CDO75535.1 - 7e-15 55.8 0.1 1.5e-14 54.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CDO75536.1 - 1.5e-86 290.6 0.0 2e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDO75536.1 - 8.4e-14 52.3 1.6 2.3e-13 50.9 0.1 2.6 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CDO75537.1 - 4.6e-78 262.7 0.0 6.2e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDO75537.1 - 1.3e-16 61.3 0.2 4.1e-16 59.7 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CDO75538.1 - 1.7e-70 237.8 0.0 9.9e-70 235.2 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDO75538.1 - 1.8e-13 51.3 0.4 7.2e-12 46.1 0.4 2.7 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribonuc_2-5A PF06479.12 CDO75539.1 - 5.9e-45 152.5 0.1 1e-44 151.8 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 CDO75539.1 - 4.4e-38 131.2 0.0 2.8e-36 125.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75539.1 - 5.1e-18 65.3 0.0 3.3e-17 62.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO75539.1 - 1.3e-05 24.2 0.0 5.6e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase PQQ PF01011.21 CDO75539.1 - 0.0012 18.6 0.0 0.013 15.4 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat Kdo PF06293.14 CDO75539.1 - 0.022 14.1 0.1 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 CDO75539.1 - 0.023 14.3 0.0 0.18 11.4 0.0 2.3 2 1 0 2 2 2 0 PQQ-like domain Cupin_1 PF00190.22 CDO75540.1 - 6.9e-43 145.8 0.1 3.1e-22 78.8 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CDO75540.1 - 4.1e-27 93.7 0.5 5.5e-14 51.6 0.1 3.3 3 0 0 3 3 3 3 Cupin domain Cupin_3 PF05899.12 CDO75540.1 - 3.5e-08 33.0 0.1 0.0025 17.5 0.1 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 CDO75540.1 - 2.5e-06 27.4 0.8 0.18 11.7 0.0 3.3 3 0 0 3 3 3 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 CDO75540.1 - 7.4e-05 22.7 0.0 0.00091 19.1 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_4 PF08007.12 CDO75540.1 - 0.046 13.2 0.1 0.17 11.3 0.1 1.8 2 0 0 2 2 2 0 Cupin superfamily protein Pirin_C PF05726.13 CDO75540.1 - 0.11 12.9 0.0 3 8.2 0.0 2.3 2 0 0 2 2 2 0 Pirin C-terminal cupin domain FAM70 PF14967.6 CDO75540.1 - 2 7.8 5.1 3.6 6.9 5.1 1.4 1 0 0 1 1 1 0 FAM70 protein NAD_binding_10 PF13460.6 CDO75541.1 - 2.2e-08 34.2 0.1 3.4e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CDO75541.1 - 7.8e-08 32.1 0.1 0.00025 20.6 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CDO75541.1 - 0.00038 20.1 0.7 0.00055 19.6 0.7 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 CDO75541.1 - 0.00098 18.2 0.0 0.99 8.4 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 CDO75541.1 - 0.0054 16.2 0.1 0.0077 15.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Fibrillarin PF01269.17 CDO75541.1 - 0.0065 15.6 0.0 0.0095 15.1 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Rossmann-like PF10727.9 CDO75541.1 - 0.017 15.0 0.4 0.026 14.4 0.4 1.3 1 0 0 1 1 1 0 Rossmann-like domain RmlD_sub_bind PF04321.17 CDO75541.1 - 0.038 13.1 0.0 0.086 11.9 0.0 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.15 CDO75541.1 - 0.19 11.9 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 CDO75541.1 - 0.22 11.1 0.1 0.34 10.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Transp_cyt_pur PF02133.15 CDO75542.1 - 3.5e-117 391.9 35.9 4e-117 391.7 35.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short_C2 PF13561.6 CDO75543.1 - 2.1e-45 155.1 0.5 3.4e-45 154.4 0.5 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO75543.1 - 1.1e-43 149.0 0.0 1.4e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO75543.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.6 CDO75543.1 - 0.0013 19.3 1.6 12 6.6 0.1 3.5 3 0 0 3 3 3 1 Helix-hairpin-helix domain Epimerase PF01370.21 CDO75543.1 - 0.0064 16.0 0.2 0.027 13.9 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CDO75543.1 - 0.019 14.9 0.2 0.27 11.1 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain B12-binding PF02310.19 CDO75543.1 - 0.029 14.4 0.1 0.061 13.4 0.1 1.5 1 0 0 1 1 1 0 B12 binding domain UPF0146 PF03686.13 CDO75543.1 - 0.081 12.8 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) CENP-F_leu_zip PF10473.9 CDO75544.1 - 0.017 15.2 7.7 0.017 15.2 7.7 4.5 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.12 CDO75544.1 - 0.2 9.8 68.3 0.003 15.8 33.8 3.0 1 1 1 3 3 3 0 HOOK protein Filament PF00038.21 CDO75544.1 - 6.8 6.2 64.4 0.34 10.4 9.4 2.3 2 0 0 2 2 2 0 Intermediate filament protein DUF4112 PF13430.6 CDO75548.1 - 2.3e-34 117.8 0.1 2.9e-34 117.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) LegC3_N PF18654.1 CDO75549.1 - 0.14 11.4 0.3 0.2 10.9 0.3 1.1 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain Fusion_F0 PF13044.6 CDO75549.1 - 2 7.0 3.9 3.9 6.0 3.9 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus Herpes_gE PF02480.16 CDO75552.1 - 0.069 11.9 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Herpes_pp85 PF04637.12 CDO75552.1 - 0.2 10.1 0.1 0.28 9.5 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Mid2 PF04478.12 CDO75553.1 - 0.042 13.7 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Alpha-amylase PF00128.24 CDO75554.1 - 4.2e-12 46.3 0.2 1.3e-08 34.9 0.0 2.7 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Fra10Ac1 PF09725.9 CDO75554.1 - 0.07 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 Sugar_tr PF00083.24 CDO75555.1 - 1.4e-77 261.5 17.7 1.6e-77 261.3 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO75555.1 - 1e-21 77.2 43.5 1.5e-19 70.2 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Exo_endo_phos PF03372.23 CDO75556.1 - 1.3e-09 38.0 0.2 2e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RuvX PF03652.15 CDO75556.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction resolvase RhoGEF PF00621.20 CDO75557.1 - 2.2e-31 109.5 1.1 3.1e-31 109.0 1.1 1.2 1 0 0 1 1 1 1 RhoGEF domain WD40 PF00400.32 CDO75557.1 - 3.3e-26 91.0 16.4 3.8e-08 33.9 0.0 8.8 9 0 0 9 9 9 6 WD domain, G-beta repeat CNH PF00780.22 CDO75557.1 - 3.9e-19 69.3 0.0 8e-19 68.3 0.0 1.5 1 1 0 1 1 1 1 CNH domain ANAPC4_WD40 PF12894.7 CDO75557.1 - 1.2e-09 38.3 0.2 0.0001 22.5 0.0 4.5 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PH_5 PF15405.6 CDO75557.1 - 3.6e-08 33.6 0.0 9.7e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PQQ_2 PF13360.6 CDO75557.1 - 2.7e-05 23.9 1.6 0.00013 21.6 0.2 2.4 1 1 1 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 CDO75557.1 - 0.00033 21.0 8.6 0.38 11.3 0.3 4.1 3 0 0 3 3 3 2 PQQ-like domain Ge1_WD40 PF16529.5 CDO75557.1 - 0.0053 15.7 0.1 0.03 13.3 0.0 2.0 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PH PF00169.29 CDO75557.1 - 0.0064 17.0 0.0 0.021 15.3 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 CDO75557.1 - 0.14 12.0 0.1 14 5.5 0.0 2.4 2 0 0 2 2 2 0 PH domain Lactonase PF10282.9 CDO75558.1 - 1.9e-10 40.5 0.0 1.6e-08 34.3 0.0 2.7 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller RdRP PF05183.12 CDO75560.1 - 3.9e-167 557.5 0.0 4.8e-167 557.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase EcoEI_R_C PF08463.10 CDO75560.1 - 0.2 11.8 0.4 0.46 10.6 0.4 1.5 1 0 0 1 1 1 0 EcoEI R protein C-terminal rve PF00665.26 CDO75561.1 - 3.3e-08 33.7 0.0 6.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 CDO75561.1 - 0.02 14.7 0.0 0.067 13.0 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain DDE_Tnp_1 PF01609.21 CDO75561.1 - 0.023 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain ELL PF10390.9 CDO75562.1 - 0.0058 16.2 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL DUF3987 PF13148.6 CDO75563.1 - 0.047 12.7 8.1 0.079 12.0 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_11 PF13086.6 CDO75563.1 - 0.98 9.1 3.7 1.7 8.4 3.7 1.3 1 0 0 1 1 1 0 AAA domain Cupin_1 PF00190.22 CDO75564.1 - 1.3e-24 86.6 0.5 2.3e-24 85.7 0.5 1.4 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 CDO75564.1 - 1.8e-05 24.4 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain SKG6 PF08693.10 CDO75564.1 - 0.17 11.3 3.1 0.33 10.4 3.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Nop14 PF04147.12 CDO75565.1 - 0.0053 15.1 3.7 0.0073 14.6 3.7 1.1 1 0 0 1 1 1 1 Nop14-like family zf-RRN7 PF11781.8 CDO75565.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-H2C2_5 PF13909.6 CDO75565.1 - 0.12 12.2 0.4 0.28 11.0 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain CDC45 PF02724.14 CDO75565.1 - 0.15 10.3 2.0 0.23 9.7 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 CDO75565.1 - 0.91 7.6 2.5 1.1 7.3 2.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apt1 PF10351.9 CDO75565.1 - 1.6 7.5 5.8 2.3 7.0 5.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Gln-synt_C PF00120.24 CDO75566.1 - 1.3e-16 60.5 0.0 8.6e-16 57.9 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CDO75566.1 - 1.4e-11 43.9 0.0 2.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain VID27 PF08553.10 CDO75567.1 - 5.4e-174 578.3 0.1 8.3e-174 577.7 0.1 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 CDO75567.1 - 4.9e-59 199.1 0.1 4.9e-59 199.1 0.1 3.3 2 1 1 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 CDO75567.1 - 8.9e-30 103.2 0.0 2.3e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 VID27 PH-like domain DNA_pol_phi PF04931.13 CDO75567.1 - 0.33 9.0 10.1 0.54 8.3 10.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi zf-3CxxC PF13695.6 CDO75569.1 - 0.069 13.6 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding domain DUF2688 PF10892.8 CDO75569.1 - 1 8.9 3.9 0.4 10.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) DUF4551 PF15087.6 CDO75569.1 - 2 7.2 9.5 2.4 6.9 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RNB PF00773.19 CDO75570.1 - 1.4e-97 326.9 0.1 2.7e-97 326.0 0.1 1.5 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 CDO75570.1 - 2.3e-25 88.8 0.1 6e-25 87.4 0.1 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 CDO75570.1 - 4.9e-25 87.4 0.0 1.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CDO75570.1 - 0.00021 21.4 0.0 0.085 13.0 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_S1 PF17215.3 CDO75570.1 - 0.00097 19.1 0.0 0.0034 17.3 0.0 2.0 1 1 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 CDO75570.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain Iso_dh PF00180.20 CDO75571.1 - 4.8e-102 341.7 0.0 5.5e-102 341.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Snf7 PF03357.21 CDO75572.1 - 1.1e-23 83.7 21.0 1.1e-23 83.7 21.0 1.5 1 1 1 2 2 2 1 Snf7 Phage_tail_APC PF16778.5 CDO75572.1 - 0.027 14.4 1.3 0.075 12.9 1.3 1.9 1 1 0 1 1 1 0 Phage tail assembly chaperone protein Sec20 PF03908.13 CDO75572.1 - 0.39 10.7 3.4 0.57 10.1 1.6 2.3 1 1 0 1 1 1 0 Sec20 GPI-anchored PF10342.9 CDO75573.1 - 0.00011 22.8 0.1 0.00028 21.6 0.1 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Exo_endo_phos PF03372.23 CDO75574.1 - 1.2e-08 34.8 0.0 2.2e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fungal_trans PF04082.18 CDO75575.1 - 3.5e-18 65.6 0.1 6.2e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med17 PF10156.9 CDO75576.1 - 5.4e-26 91.3 0.0 7.2e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Ribosomal_L5e PF17144.4 CDO75577.1 - 2.5e-82 274.7 0.2 4.5e-82 273.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CDO75577.1 - 5.1e-36 123.5 2.3 5.1e-36 123.5 2.3 2.0 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region K_oxygenase PF13434.6 CDO75577.1 - 0.044 12.9 0.7 0.06 12.5 0.1 1.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) MtrA PF04208.14 CDO75577.1 - 0.17 11.5 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A RRM_1 PF00076.22 CDO75578.1 - 1.3e-14 53.7 0.0 1.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trnau1ap PF17654.1 CDO75578.1 - 0.3 12.0 5.8 0.47 11.3 5.8 1.4 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins CTNNBL PF08216.11 CDO75579.1 - 2.3e-33 114.5 0.0 1e-32 112.4 0.0 2.2 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 CDO75579.1 - 0.0016 18.4 0.1 0.19 11.8 0.0 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Mo25 PF08569.11 CDO75579.1 - 0.0094 15.4 0.1 0.018 14.4 0.1 1.6 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.6 CDO75579.1 - 0.038 14.4 1.1 28 5.2 0.0 4.2 5 0 0 5 5 5 0 HEAT repeats UNC45-central PF11701.8 CDO75579.1 - 0.064 13.2 0.2 0.75 9.8 0.0 2.5 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central AAA_28 PF13521.6 CDO75579.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 CDO75580.1 - 9.4e-22 76.9 3.6 0.00014 22.6 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat UTP15_C PF09384.10 CDO75580.1 - 9.2e-10 38.4 0.5 1.6e-09 37.6 0.5 1.4 1 0 0 1 1 1 1 UTP15 C terminal ANAPC4_WD40 PF12894.7 CDO75580.1 - 2e-09 37.6 0.0 0.0069 16.7 0.0 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CDO75580.1 - 0.00088 17.9 0.3 0.048 12.2 0.1 2.3 2 1 0 2 2 2 2 Cytochrome D1 heme domain TCTP PF00838.17 CDO75581.1 - 3e-75 252.1 3.1 3.3e-75 252.0 3.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Alpha_TIF PF02232.15 CDO75581.1 - 0.056 12.6 0.1 0.063 12.4 0.1 1.1 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) Thioredoxin PF00085.20 CDO75582.1 - 7.5e-59 196.1 0.1 2.3e-29 101.4 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CDO75582.1 - 1.5e-42 145.6 0.0 1.3e-33 116.5 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CDO75582.1 - 1.8e-07 31.2 0.1 0.0024 18.0 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CDO75582.1 - 5.9e-07 29.7 0.2 0.059 13.7 0.0 4.1 5 0 0 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CDO75582.1 - 1.1e-06 29.0 0.4 0.051 14.0 0.1 3.7 3 1 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CDO75582.1 - 3.2e-06 27.1 0.2 0.011 15.7 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 CDO75582.1 - 1.6e-05 24.6 0.5 0.1 12.3 0.1 3.4 3 0 0 3 3 3 2 Redoxin Calsequestrin PF01216.17 CDO75582.1 - 0.025 13.6 0.3 0.076 12.0 0.1 1.8 2 0 0 2 2 2 0 Calsequestrin Thioredoxin_4 PF13462.6 CDO75582.1 - 0.15 12.2 0.8 18 5.5 0.1 3.3 3 1 1 4 4 4 0 Thioredoxin DUF3325 PF11804.8 CDO75583.1 - 0.26 11.5 3.2 4 7.6 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) FAT PF02259.23 CDO75584.1 - 3.5e-72 243.5 6.4 7.5e-72 242.4 6.1 1.7 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 CDO75584.1 - 4.6e-11 43.0 0.0 1.3e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CDO75584.1 - 0.0061 16.3 0.1 0.023 14.5 0.1 2.1 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CDO75584.1 - 0.037 14.3 0.1 1 9.8 0.0 3.8 2 0 0 2 2 2 0 HEAT repeat TPR_2 PF07719.17 CDO75584.1 - 0.064 13.4 1.5 0.58 10.4 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDO75584.1 - 0.078 13.2 1.6 2.1 8.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Bromodomain PF00439.25 CDO75585.1 - 2.7e-22 78.6 0.2 4.9e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 Bromodomain Asp PF00026.23 CDO75586.1 - 4.4e-112 374.6 0.2 5.2e-112 374.3 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO75586.1 - 6e-16 59.2 0.4 8.5e-14 52.2 0.4 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDO75586.1 - 0.00016 21.5 0.0 0.0041 16.9 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CDO75586.1 - 0.0011 19.6 0.1 0.83 10.3 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CDO75586.1 - 0.0016 19.0 0.0 1.5 9.4 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease WD40 PF00400.32 CDO75587.1 - 0.046 14.6 0.1 6.4 7.8 0.1 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat DAP_epimerase PF01678.19 CDO75587.1 - 0.085 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Diaminopimelate epimerase Pkinase PF00069.25 CDO75588.1 - 5.4e-77 258.7 0.0 6.9e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75588.1 - 1.1e-38 133.0 0.0 1.5e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO75588.1 - 1.9e-07 30.7 0.1 1.3e-06 27.9 0.1 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CDO75588.1 - 0.00023 20.2 0.1 0.0027 16.7 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDO75588.1 - 0.0027 17.1 0.6 0.0074 15.7 0.6 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDO75588.1 - 0.0066 15.3 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PCI PF01399.27 CDO75589.1 - 2.5e-12 47.2 0.0 1.4e-11 44.8 0.0 2.2 2 0 0 2 2 2 1 PCI domain Cohesin_load PF10345.9 CDO75589.1 - 0.023 13.2 0.1 0.04 12.4 0.1 1.4 1 0 0 1 1 1 0 Cohesin loading factor RPN7 PF10602.9 CDO75589.1 - 0.044 13.5 0.2 0.1 12.3 0.2 1.7 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_14 PF13428.6 CDO75589.1 - 0.36 11.8 4.2 11 7.2 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TAFH PF07531.14 CDO75589.1 - 0.43 10.7 3.2 1.3 9.1 0.1 2.9 3 0 0 3 3 3 0 NHR1 homology to TAF YkpC PF17447.2 CDO75590.1 - 0.39 11.6 4.0 5.3 8.1 0.4 4.5 2 0 0 2 2 2 0 Uncharacterized YkpC-like SNF2_N PF00176.23 CDO75591.1 - 3e-13 49.2 0.0 3e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2439 PF10382.9 CDO75591.1 - 4.7e-06 26.8 0.7 0.0067 16.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2439) Helicase_C PF00271.31 CDO75592.1 - 4.4e-14 52.8 0.0 8.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CDO75592.1 - 8.5e-06 25.1 0.0 2e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PUB PF09409.10 CDO75593.1 - 4.2e-08 33.0 0.0 7.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 PUB domain HTH_13 PF11972.8 CDO75593.1 - 0.056 13.5 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 HTH DNA binding domain PUB PF09409.10 CDO75594.1 - 1.4e-09 37.7 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 PUB domain Chorion_2 PF03964.15 CDO75594.1 - 8.5 7.3 9.1 2 9.3 1.1 2.4 2 0 0 2 2 2 0 Chorion family 2 DUF3336 PF11815.8 CDO75595.1 - 2.8e-46 156.7 1.5 4.4e-46 156.0 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CDO75595.1 - 2.4e-19 70.3 0.1 7.4e-19 68.7 0.1 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase CAP_N PF01213.19 CDO75595.1 - 0.055 12.9 2.2 0.095 12.2 2.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3759 PF12585.8 CDO75598.1 - 2.8e-38 129.9 6.2 3.3e-38 129.6 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) TetR_C_31 PF17940.1 CDO75598.1 - 0.07 13.3 0.0 0.079 13.2 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain BCDHK_Adom3 PF10436.9 CDO75599.1 - 2.4e-30 105.5 0.0 3.9e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CDO75599.1 - 3.5e-09 37.1 0.0 6.9e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CDO75599.1 - 0.0026 17.6 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 CDO75601.1 - 9.6e-65 218.6 0.1 1.4e-43 149.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75601.1 - 1.3e-28 100.1 0.1 2.5e-21 76.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CDO75601.1 - 2.8e-07 29.8 0.1 4.1e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CDO75601.1 - 0.0001 21.7 0.6 0.0015 17.9 0.0 2.3 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO75601.1 - 0.0015 18.5 2.9 0.091 12.7 2.2 2.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDO75601.1 - 0.008 15.5 0.0 0.024 14.0 0.0 1.8 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDO75601.1 - 0.032 13.8 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 CDO75601.1 - 0.047 12.5 0.9 0.097 11.4 0.9 1.7 1 1 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CDO75601.1 - 0.055 12.4 0.1 0.092 11.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 CDO75601.1 - 0.062 12.4 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 CDO75601.1 - 0.13 13.0 0.2 0.33 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain DUF3818 PF12825.7 CDO75602.1 - 6.8e-129 429.7 0.1 1.1e-120 402.8 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CDO75602.1 - 2e-34 118.4 1.2 3.8e-34 117.5 1.2 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 CDO75602.1 - 4e-11 42.9 0.1 3.8e-10 39.7 0.1 2.5 1 1 0 1 1 1 1 PX domain TPR_7 PF13176.6 CDO75602.1 - 0.11 12.5 0.2 0.42 10.8 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1682 PF07946.14 CDO75603.1 - 1.7e-55 188.5 0.0 2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF677 PF05055.12 CDO75606.1 - 0.0028 16.6 0.4 0.0041 16.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) ApoLp-III PF07464.11 CDO75606.1 - 0.025 14.6 0.7 0.046 13.8 0.7 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Rx_N PF18052.1 CDO75606.1 - 0.063 13.5 4.5 0.39 11.0 0.1 3.0 1 1 2 3 3 3 0 Rx N-terminal domain Dak2 PF02734.17 CDO75606.1 - 0.19 11.6 7.4 0.96 9.3 1.9 2.4 2 1 1 3 3 3 0 DAK2 domain DUF1664 PF07889.12 CDO75606.1 - 0.39 10.8 1.5 18 5.4 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 CDO75606.1 - 0.63 9.9 18.7 2.8 7.8 18.8 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 CDO75606.1 - 4.3 8.0 10.4 0.42 11.2 3.5 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ribosomal_L29 PF00831.23 CDO75608.1 - 8.7e-09 35.2 0.6 8.7e-09 35.2 0.6 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein TolA_bind_tri PF16331.5 CDO75608.1 - 0.11 12.6 2.1 0.49 10.5 0.5 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation Pkinase PF00069.25 CDO75609.1 - 2e-57 194.5 0.0 1.4e-45 155.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75609.1 - 2.3e-36 125.4 0.0 2.6e-30 105.6 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO75609.1 - 0.00055 18.8 0.0 0.001 17.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CDO75609.1 - 0.00075 18.9 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Polysacc_deac_1 PF01522.21 CDO75610.1 - 1.4e-22 79.9 0.0 3.4e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Raftlin PF15250.6 CDO75610.1 - 0.094 11.4 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Raftlin Kei1 PF08552.11 CDO75610.1 - 0.15 11.9 0.8 0.24 11.3 0.8 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SPX PF03105.19 CDO75610.1 - 0.94 9.3 6.4 1.2 9.0 6.4 1.1 1 0 0 1 1 1 0 SPX domain TFIIF_alpha PF05793.12 CDO75611.1 - 6.1e-12 44.9 56.4 3.6e-10 39.1 5.8 4.2 2 2 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF0029 PF01205.19 CDO75611.1 - 0.057 13.8 2.6 6.4 7.2 0.9 2.5 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 V-set PF07686.17 CDO75611.1 - 0.12 12.6 0.0 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 Immunoglobulin V-set domain PQQ_3 PF13570.6 CDO75611.1 - 0.12 12.9 0.2 0.37 11.3 0.2 1.8 1 0 0 1 1 1 0 PQQ-like domain HLH PF00010.26 CDO75612.1 - 3.1e-13 49.4 0.5 6.7e-13 48.4 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_L7Ae PF01248.26 CDO75613.1 - 2.5e-25 88.0 1.0 2.5e-25 88.0 1.0 2.4 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SNARE PF05739.19 CDO75613.1 - 1.5 8.9 4.9 9.2 6.4 0.1 2.9 2 1 1 3 3 3 0 SNARE domain DFP PF04127.15 CDO75614.1 - 0.059 13.2 3.0 0.069 13.0 1.5 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF5624 PF18538.1 CDO75614.1 - 0.31 11.2 1.8 0.76 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Tup_N PF08581.10 CDO75614.1 - 0.34 11.2 16.3 2.7 8.4 5.2 3.6 3 0 0 3 3 3 0 Tup N-terminal DUF5517 PF17639.2 CDO75614.1 - 4 7.8 11.3 3.9 7.8 1.3 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5517) UPF0184 PF03670.13 CDO75614.1 - 6.3 7.3 9.9 83 3.7 5.6 3.8 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0184) 5_nucleotid PF05761.14 CDO75614.1 - 6.5 5.5 10.8 44 2.8 10.8 2.1 1 1 0 1 1 1 0 5' nucleotidase family RFX_DNA_binding PF02257.15 CDO75615.1 - 1.1e-27 96.5 0.1 3e-27 95.1 0.1 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain NuDC PF16273.5 CDO75615.1 - 0.18 12.4 0.7 0.35 11.4 0.7 1.4 1 0 0 1 1 1 0 Nuclear distribution C domain Peptidase_M16_M PF16187.5 CDO75620.1 - 1.9e-72 243.9 0.0 3.1e-72 243.2 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CDO75620.1 - 1.6e-15 57.6 0.0 5.9e-06 26.4 0.0 3.4 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CDO75620.1 - 1.9e-15 57.1 0.0 3.2e-14 53.1 0.0 2.3 1 1 1 2 2 2 1 Insulinase (Peptidase family M16) zf_Rg PF17915.1 CDO75621.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Reverse gyrase zinc finger Amidase PF01425.21 CDO75622.1 - 5.8e-21 75.0 0.0 1.3e-13 50.8 0.0 2.1 1 1 1 2 2 2 2 Amidase F-box-like PF12937.7 CDO75623.1 - 0.0051 16.7 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like CH PF00307.31 CDO75625.1 - 7.7e-83 273.8 0.0 8.3e-21 74.2 0.0 5.2 5 1 0 5 5 5 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CDO75625.1 - 4e-10 39.4 0.0 0.3 10.9 0.0 4.7 4 0 0 4 4 4 4 CAMSAP CH domain CH_2 PF06294.11 CDO75625.1 - 0.046 13.8 0.0 3.2 7.9 0.0 2.9 3 0 0 3 3 3 0 CH-like domain in sperm protein FKBP_C PF00254.28 CDO75626.1 - 1.4e-32 111.9 0.0 1.6e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GST_N_3 PF13417.6 CDO75627.1 - 1.3e-07 31.9 0.0 2.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO75627.1 - 6.1e-07 29.6 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO75627.1 - 0.0018 18.3 0.4 0.0044 17.0 0.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Bestrophin PF01062.21 CDO75628.1 - 4.6e-34 118.2 5.6 4.4e-18 65.7 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF4149 PF13664.6 CDO75628.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF572 PF04502.13 CDO75630.1 - 1.8 8.1 25.6 0.3 10.7 21.3 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF572) CDC45 PF02724.14 CDO75630.1 - 7.7 4.7 17.8 12 4.1 17.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Dimer_Tnp_hAT PF05699.14 CDO75632.1 - 2e-17 62.7 0.0 4.6e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FAP PF07174.11 CDO75634.1 - 2.8 7.3 14.4 4.2 6.8 14.4 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ribosomal_L16 PF00252.18 CDO75635.1 - 1.5e-40 138.3 0.0 1.8e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e YscO-like PF16789.5 CDO75636.1 - 0.0058 16.7 0.4 0.0058 16.7 0.4 2.0 1 1 1 2 2 2 1 YscO-like protein DUF5371 PF17341.2 CDO75636.1 - 0.0096 16.1 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5371) ThiG PF05690.14 CDO75636.1 - 0.056 12.8 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PRP3 PF08572.10 CDO75637.1 - 8.2e-62 208.9 3.6 8.2e-62 208.9 3.6 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CDO75637.1 - 1.6e-46 158.0 0.1 1.6e-46 158.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DCP1 PF06058.13 CDO75638.1 - 4.7e-23 81.3 0.0 4.4e-22 78.2 0.0 2.1 1 1 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 CDO75638.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus DUF2868 PF11067.8 CDO75638.1 - 1.3 8.5 5.6 0.17 11.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) TPX2 PF06886.11 CDO75638.1 - 6.5 7.1 8.8 7.4 6.9 1.9 2.3 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) DDE_3 PF13358.6 CDO75639.1 - 1.6e-10 40.9 0.0 2.9e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CDO75639.1 - 4.6e-07 30.0 0.0 1.4e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 CDO75640.1 - 3.6e-12 46.3 0.5 4.1e-12 46.1 0.5 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Acetone_carb_G PF08882.11 CDO75641.1 - 0.014 15.5 1.0 0.027 14.6 0.1 1.8 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit bZIP_1 PF00170.21 CDO75641.1 - 0.045 13.9 0.4 0.045 13.9 0.4 2.0 2 0 0 2 2 2 0 bZIP transcription factor SOTI PF17079.5 CDO75641.1 - 0.52 10.8 2.8 31 5.1 0.1 3.1 3 0 0 3 3 3 0 Male-specific protein scotti Med12 PF09497.10 CDO75642.1 - 1.2e-26 92.8 0.1 3.4e-26 91.3 0.1 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 CDO75642.1 - 2.6e-06 26.6 0.0 1.1e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain AIG1 PF04548.16 CDO75642.1 - 0.24 10.7 0.3 0.5 9.7 0.3 1.5 1 0 0 1 1 1 0 AIG1 family Ribosomal_S7 PF00177.21 CDO75644.1 - 2.5e-36 124.6 1.3 3.3e-36 124.2 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RRM_1 PF00076.22 CDO75645.1 - 2.5e-05 24.0 0.0 6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0242 PF06785.11 CDO75645.1 - 0.58 10.2 4.9 0.92 9.6 4.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 CDO75645.1 - 1.1 8.5 5.2 1.8 7.8 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 CDO75645.1 - 1.3 7.5 6.3 1.8 7.0 6.3 1.2 1 0 0 1 1 1 0 Macoilin family ADIP PF11559.8 CDO75645.1 - 1.8 8.7 10.9 3.4 7.7 10.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 CDO75645.1 - 3.2 7.5 7.6 5.2 6.9 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SRP-alpha_N PF04086.13 CDO75648.1 - 8 6.3 17.9 11 5.8 17.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Bax1-I PF01027.20 CDO75649.1 - 1.4e-41 142.7 26.7 1.7e-41 142.3 26.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 CDO75649.1 - 7e-08 32.3 7.1 9.7e-08 31.9 7.1 1.3 1 0 0 1 1 1 1 Bax inhibitor 1 like MFS_1 PF07690.16 CDO75650.1 - 1.3e-28 100.0 38.3 4.4e-26 91.6 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2109 PF09882.9 CDO75650.1 - 7.7 6.6 11.1 0.53 10.3 0.2 3.8 4 0 0 4 4 4 0 Predicted membrane protein (DUF2109) MDM31_MDM32 PF08118.11 CDO75651.1 - 2.8e-214 712.7 0.0 3.2e-214 712.5 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins DUF2095 PF09868.9 CDO75651.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) CMAS PF02353.20 CDO75652.1 - 2.6e-08 33.5 0.1 6.2e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase F-box PF00646.33 CDO75652.1 - 0.0013 18.5 0.3 0.004 17.0 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CDO75652.1 - 0.062 13.2 0.6 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 F-box-like KDZ PF18758.1 CDO75653.1 - 1.2e-88 296.5 0.0 2.4e-88 295.5 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 CDO75653.1 - 0.00079 19.5 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 CDO75654.1 - 0.041 14.2 1.1 0.81 10.0 0.3 2.3 2 0 0 2 2 2 0 Caulimovirus viroplasmin HMG_box_2 PF09011.10 CDO75655.1 - 0.0015 19.0 0.2 0.0015 19.0 0.2 3.0 3 0 0 3 3 3 1 HMG-box domain AAT PF03417.16 CDO75655.1 - 0.046 13.4 0.3 0.077 12.7 0.3 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase HMG_box PF00505.19 CDO75655.1 - 0.067 13.6 0.6 0.067 13.6 0.6 3.1 3 1 0 3 3 3 0 HMG (high mobility group) box Apolipoprotein PF01442.18 CDO75655.1 - 0.31 10.9 5.1 2.1 8.2 0.2 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain adh_short PF00106.25 CDO75656.1 - 7.3e-12 45.1 0.0 5e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO75656.1 - 2.7e-09 36.9 0.0 2e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO75656.1 - 9.2e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 KR domain RPA43_OB PF17875.1 CDO75657.1 - 1.4e-25 90.3 2.1 7.1e-25 88.0 0.0 2.3 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 CDO75657.1 - 0.00037 20.8 0.0 0.00088 19.6 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Rrn6 PF10214.9 CDO75657.1 - 0.057 11.9 0.4 0.066 11.7 0.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Pam16 PF03656.13 CDO75658.1 - 1.3e-18 67.2 1.6 1.4e-17 63.9 1.5 2.2 1 1 0 1 1 1 1 Pam16 DGF-1_C PF11040.8 CDO75658.1 - 0.65 10.0 4.2 5.9 7.0 2.3 2.2 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF812 PF05667.11 CDO75659.1 - 0.023 13.6 18.6 0.037 12.9 18.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3619 PF12279.8 CDO75659.1 - 0.28 11.5 0.1 0.28 11.5 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) DUF1043 PF06295.12 CDO75659.1 - 0.74 9.8 5.6 1 9.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) NIF PF03031.18 CDO75660.1 - 3.5e-16 59.4 0.1 6e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase KTI12 PF08433.10 CDO75661.1 - 5.7e-54 183.4 0.0 7.8e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Glyco_hydro_16 PF00722.21 CDO75663.1 - 3.1e-06 26.8 0.0 4.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Transposase_21 PF02992.14 CDO75664.1 - 4.8e-10 39.0 0.0 1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 CDO75664.1 - 0.00014 21.2 1.1 0.0003 20.1 1.1 1.5 1 0 0 1 1 1 1 Plavaka transposase T2SSM PF04612.12 CDO75664.1 - 0.011 15.8 0.1 0.028 14.5 0.1 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Asp PF00026.23 CDO75666.1 - 6.5e-70 236.0 0.4 8.8e-70 235.6 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO75666.1 - 9.3e-11 42.3 6.9 5e-06 26.9 2.8 3.8 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO75666.1 - 0.0034 18.0 0.0 0.66 10.7 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease PTPLA PF04387.14 CDO75667.1 - 1.2e-57 194.3 8.2 2e-57 193.5 8.2 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA bZIP_1 PF00170.21 CDO75667.1 - 6e-06 26.3 10.8 1.2e-05 25.3 8.8 2.0 1 1 1 2 2 2 1 bZIP transcription factor NAM-associated PF14303.6 CDO75667.1 - 0.034 14.9 0.2 0.051 14.3 0.2 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4110 PF13422.6 CDO75667.1 - 0.22 11.6 2.9 0.51 10.4 2.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) Aminopep PF10023.9 CDO75667.1 - 0.62 9.4 4.3 1.1 8.5 2.9 1.9 2 0 0 2 2 2 0 Putative aminopeptidase Metal_resist PF13801.6 CDO75667.1 - 8.3 6.6 14.6 61 3.8 14.6 2.2 1 1 0 1 1 1 0 Heavy-metal resistance NIF PF03031.18 CDO75668.1 - 1.7e-54 183.8 0.1 2.3e-54 183.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 CDO75668.1 - 0.024 15.0 0.1 0.15 12.4 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase RhoGAP PF00620.27 CDO75669.1 - 5.5e-39 133.4 0.1 1.9e-38 131.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.22 CDO75669.1 - 8.7e-07 28.7 20.2 3.2e-06 26.9 8.2 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.22 CDO75669.1 - 3.2e-05 24.0 4.8 3.2e-05 24.0 4.8 2.2 2 0 0 2 2 2 1 LIM domain C1_2 PF03107.16 CDO75669.1 - 0.0029 17.9 1.9 0.0029 17.9 1.9 2.4 2 0 0 2 2 2 1 C1 domain NYD-SP28_assoc PF14775.6 CDO75669.1 - 0.72 10.0 7.9 3.8 7.7 2.6 2.9 2 1 0 2 2 2 0 Sperm tail C-terminal domain DUF5595 PF18077.1 CDO75669.1 - 1.1 9.4 2.6 19 5.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Seryl_tRNA_N PF02403.22 CDO75669.1 - 2.7 8.3 17.6 1 9.6 3.9 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AKNA PF12443.8 CDO75669.1 - 2.9 8.6 9.5 11 6.7 0.5 3.4 3 0 0 3 3 2 0 AT-hook-containing transcription factor K_channel_TID PF07941.11 CDO75669.1 - 3.7 8.1 17.2 0.5 10.9 11.8 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-C3HC4_3 PF13920.6 CDO75669.1 - 4 7.4 13.2 1.1 9.2 4.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Gp-FAR-1 PF05823.12 CDO75669.1 - 4.4 7.6 7.0 0.39 11.1 0.8 2.1 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2318 PF10080.9 CDO75669.1 - 6.3 7.0 12.1 3.1 8.0 2.2 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) GAS PF13851.6 CDO75669.1 - 7.7 5.8 21.7 8.3 5.7 5.5 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding BTB PF00651.31 CDO75670.1 - 4.3e-13 49.5 0.0 1e-06 28.9 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Carbam_trans_C PF16861.5 CDO75670.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase C-terminus Glyco_hydro_18 PF00704.28 CDO75671.1 - 2.4e-10 40.6 2.2 1.5e-09 38.0 2.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 HMMR_C PF15908.5 CDO75672.1 - 0.00026 21.3 7.9 0.00026 21.3 7.9 4.8 3 3 1 4 4 4 1 Hyaluronan mediated motility receptor C-terminal SHIPPO-rpt PF07004.12 CDO75672.1 - 0.089 13.7 1.0 0.18 12.8 1.0 1.5 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat DUF3584 PF12128.8 CDO75672.1 - 0.12 9.8 78.8 0.17 9.4 22.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) LOB PF03195.14 CDO75672.1 - 0.2 12.2 2.2 0.55 10.8 0.6 2.7 2 0 0 2 2 2 0 Lateral organ boundaries (LOB) domain MscS_porin PF12795.7 CDO75672.1 - 1.4 8.4 88.8 0.071 12.6 0.5 4.7 3 2 1 4 4 4 0 Mechanosensitive ion channel porin domain GPI-anchored PF10342.9 CDO75673.1 - 0.084 13.6 0.3 0.12 13.1 0.3 1.3 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Rad21_Rec8_N PF04825.13 CDO75674.1 - 5.9e-38 129.4 0.3 1e-37 128.7 0.3 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CDO75674.1 - 1.9e-13 49.5 0.2 4.5e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein PPR_2 PF13041.6 CDO75675.1 - 1.5e-41 140.3 1.1 1.8e-10 40.9 0.0 8.5 3 2 5 8 8 8 7 PPR repeat family PPR_3 PF13812.6 CDO75675.1 - 5.4e-40 135.3 0.8 2.6e-08 33.8 0.0 7.1 5 2 2 7 7 7 5 Pentatricopeptide repeat domain PPR_long PF17177.4 CDO75675.1 - 1.3e-24 86.8 0.8 9.7e-09 34.9 0.0 3.3 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CDO75675.1 - 3e-18 65.2 0.0 0.0016 18.1 0.0 7.1 7 0 0 7 7 7 4 PPR repeat PPR PF01535.20 CDO75675.1 - 6e-14 51.2 15.6 0.00012 22.0 0.1 8.9 11 0 0 11 11 11 4 PPR repeat BKACE PF05853.12 CDO75675.1 - 0.0064 15.8 1.4 0.16 11.2 0.7 3.2 2 2 1 3 3 3 1 beta-keto acid cleavage enzyme ECSIT PF06239.11 CDO75675.1 - 0.014 14.5 0.5 1.6 7.8 0.1 3.6 3 1 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway Exog_C PF18026.1 CDO75675.1 - 0.027 14.5 0.0 2.3 8.4 0.0 3.7 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain GMP_synt_C PF00958.22 CDO75675.1 - 0.12 12.5 0.0 26 4.9 0.0 3.2 2 1 1 3 3 3 0 GMP synthase C terminal domain R3H-assoc PF13902.6 CDO75677.1 - 0.08 13.3 0.3 0.16 12.4 0.3 1.5 1 0 0 1 1 1 0 R3H-associated N-terminal domain Chitin_synth_1 PF01644.17 CDO75678.1 - 9.7e-77 256.5 0.1 1.5e-76 255.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CDO75678.1 - 5.6e-26 90.3 1.6 1.7e-25 88.7 0.1 2.7 3 0 0 3 3 3 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CDO75678.1 - 2.5e-24 85.8 8.1 2.2e-17 62.9 0.0 2.1 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CDO75678.1 - 3.9e-05 23.7 7.5 0.00041 20.3 7.5 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CDO75678.1 - 0.14 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Lactamase_B PF00753.27 CDO75679.1 - 2.6e-19 70.0 1.9 3.9e-19 69.5 1.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDO75679.1 - 0.0012 18.4 0.3 0.0017 17.9 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain F-box PF00646.33 CDO75680.1 - 0.0093 15.8 0.4 0.16 11.9 0.4 2.5 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO75680.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like PRP8_domainIV PF12134.8 CDO75681.1 - 0.04 13.6 0.2 0.064 12.9 0.2 1.2 1 0 0 1 1 1 0 PRP8 domain IV core Inhibitor_I9 PF05922.16 CDO75682.1 - 0.0023 18.5 0.1 0.0056 17.3 0.1 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I9 HhH-GPD PF00730.25 CDO75683.1 - 2.7e-09 37.4 0.0 1.3e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DUF680 PF05079.12 CDO75683.1 - 1.7 9.4 4.0 17 6.2 3.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF680) Pkinase PF00069.25 CDO75684.1 - 1.6e-52 178.5 0.0 8.5e-37 126.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO75684.1 - 2.3e-19 69.7 0.0 6.4e-19 68.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO75684.1 - 0.0002 21.4 0.1 0.0004 20.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDO75684.1 - 0.00053 19.4 0.0 0.00079 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDO75684.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family SMC_ScpB PF04079.16 CDO75684.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Kdo PF06293.14 CDO75684.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 CDO75684.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Oxidored_q6 PF01058.22 CDO75685.1 - 4.9e-22 78.2 0.0 7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DEC-1_C PF04626.13 CDO75685.1 - 0.15 12.5 0.4 3.1 8.2 0.1 2.2 2 0 0 2 2 2 0 Dec-1 protein, C terminal region Mnd1 PF03962.15 CDO75687.1 - 2.2e-18 66.3 0.2 2.2e-18 66.3 0.2 1.7 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 CDO75687.1 - 4.3e-09 36.3 0.3 9e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Snapin_Pallidin PF14712.6 CDO75687.1 - 0.047 14.1 4.2 0.092 13.2 4.2 1.5 1 0 0 1 1 1 0 Snapin/Pallidin Spc7 PF08317.11 CDO75687.1 - 0.81 8.5 6.4 1.3 7.9 6.4 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 CDO75687.1 - 1.8 9.0 9.4 2.2 8.8 4.3 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Sec34 PF04136.15 CDO75690.1 - 2.6e-49 166.9 0.7 6.6e-49 165.6 0.7 1.7 1 0 0 1 1 1 1 Sec34-like family DUF1664 PF07889.12 CDO75690.1 - 0.0042 17.1 0.1 0.017 15.2 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 CDO75690.1 - 0.057 13.2 1.5 0.13 12.0 1.5 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SKA2 PF16740.5 CDO75690.1 - 0.58 10.0 3.5 0.71 9.7 0.3 2.8 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 SapB_1 PF05184.15 CDO75690.1 - 5.4 7.1 8.7 11 6.2 0.0 4.7 5 0 0 5 5 5 0 Saposin-like type B, region 1 Ricin_B_lectin PF00652.22 CDO75691.1 - 7.4e-07 29.5 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Sec2p PF06428.11 CDO75692.1 - 4.3e-10 39.4 11.9 4.3e-10 39.4 11.9 3.4 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p DUF4140 PF13600.6 CDO75692.1 - 0.04 14.4 0.7 0.04 14.4 0.7 3.8 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) CENP-H PF05837.12 CDO75692.1 - 0.13 12.7 21.9 0.18 12.2 10.6 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) NAP PF00956.18 CDO75692.1 - 0.32 10.1 3.3 0.53 9.4 3.3 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF1664 PF07889.12 CDO75692.1 - 0.48 10.5 7.5 1.7 8.7 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) EzrA PF06160.12 CDO75692.1 - 0.5 8.5 18.6 0.08 11.1 10.8 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA HSP70 PF00012.20 CDO75692.1 - 0.58 8.3 9.2 0.93 7.6 9.2 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF5339 PF17274.2 CDO75692.1 - 1.4 9.9 10.2 16 6.4 4.6 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5339) YabA PF06156.13 CDO75692.1 - 1.5 9.5 13.8 8.5 7.1 7.9 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 CDO75692.1 - 3.1 6.6 21.6 6.2 5.6 0.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 CDO75692.1 - 6.8 4.1 20.1 0.2 9.1 9.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 CDO75692.1 - 6.9 6.1 13.4 1.2 8.7 5.0 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_11 PF13086.6 CDO75692.1 - 7.9 6.2 10.3 0.33 10.7 3.3 1.9 2 0 0 2 2 2 0 AAA domain PWWP PF00855.17 CDO75693.1 - 4.5e-21 75.0 0.2 4.5e-21 75.0 0.2 2.3 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 CDO75693.1 - 0.00014 21.8 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TPR_9 PF13371.6 CDO75693.1 - 0.099 12.8 0.6 0.23 11.7 0.6 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat YL1 PF05764.13 CDO75693.1 - 7.3 6.6 32.8 0.14 12.3 22.3 2.3 2 0 0 2 2 2 0 YL1 nuclear protein DIOX_N PF14226.6 CDO75694.1 - 3.6e-30 105.1 0.0 6.5e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO75694.1 - 2e-17 63.5 0.0 3.3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LCAT PF02450.15 CDO75696.1 - 6.3e-44 150.7 1.1 2.3e-26 92.9 0.3 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase EB1 PF03271.17 CDO75696.1 - 0.051 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 EB1-like C-terminal motif Trp_halogenase PF04820.14 CDO75697.1 - 1.3e-28 100.1 0.7 3.5e-13 49.2 0.0 3.9 2 2 0 3 3 3 2 Tryptophan halogenase FAD_binding_3 PF01494.19 CDO75697.1 - 7e-11 42.0 0.0 3.4e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CDO75697.1 - 9.6e-08 32.1 0.2 1.1e-06 28.7 0.1 2.8 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDO75697.1 - 1.7e-05 24.6 0.2 0.00063 19.4 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CDO75697.1 - 7.7e-05 22.1 0.0 0.00018 20.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDO75697.1 - 0.0005 18.9 0.1 0.001 17.9 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 CDO75697.1 - 0.0009 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 CDO75697.1 - 0.0012 18.3 0.2 0.0021 17.5 0.1 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDO75697.1 - 0.0067 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 CDO75697.1 - 0.09 12.8 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sensor PF13796.6 CDO75698.1 - 0.0012 18.9 0.7 0.0012 18.9 0.7 1.8 2 0 0 2 2 2 1 Putative sensor RNaseH_like PF04308.12 CDO75698.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease H-like REV PF00424.18 CDO75698.1 - 1.7 8.8 5.8 0.88 9.6 2.2 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) IGPS PF00218.21 CDO75699.1 - 1e-86 290.2 0.0 1.4e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 CDO75699.1 - 3.4e-16 59.6 1.3 6.1e-16 58.8 1.3 1.4 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 CDO75699.1 - 2.9e-15 56.6 0.0 3.2e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase class-I QRPTase_C PF01729.19 CDO75699.1 - 0.0015 18.4 0.2 0.041 13.7 0.0 2.4 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain TMP-TENI PF02581.17 CDO75699.1 - 0.051 12.9 0.7 1.3 8.3 0.0 2.7 3 0 0 3 3 3 0 Thiamine monophosphate synthase G-alpha PF00503.20 CDO75701.1 - 4.6e-121 404.3 0.0 5.4e-121 404.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDO75701.1 - 1.7e-16 60.2 1.1 1.1e-11 44.6 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CDO75701.1 - 4.1e-05 23.1 1.3 0.002 17.5 0.0 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 CDO75701.1 - 0.0033 17.6 1.0 1.9 8.7 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 CDO75701.1 - 0.033 14.0 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger MMR_HSR1 PF01926.23 CDO75701.1 - 0.044 13.9 0.1 1.4 9.0 0.1 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CDO75701.1 - 0.05 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CDO75701.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family BCS1_N PF08740.11 CDO75702.1 - 4.3e-37 127.9 2.0 4.3e-37 127.9 2.0 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 CDO75702.1 - 1.6e-14 54.4 0.0 1.6e-06 28.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CDO75702.1 - 0.00027 20.2 0.0 0.00057 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 CDO75702.1 - 0.00076 19.2 0.1 0.021 14.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 CDO75702.1 - 0.0068 16.2 0.1 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CDO75702.1 - 0.0069 16.8 0.1 0.0069 16.8 0.1 2.7 2 2 0 2 2 1 1 AAA ATPase domain ABC_tran PF00005.27 CDO75702.1 - 0.038 14.5 1.1 0.088 13.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 CDO75702.1 - 0.043 14.3 12.4 2.4 8.6 8.4 2.8 2 1 0 2 2 2 0 AAA domain CPSF100_C PF13299.6 CDO75702.1 - 0.44 10.7 6.9 8.8 6.5 4.6 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AAA_11 PF13086.6 CDO75702.1 - 1.4 8.6 7.1 39 3.9 0.0 3.0 3 1 0 3 3 3 0 AAA domain EVC2_like PF12297.8 CDO75702.1 - 3.3 6.3 12.2 17 4.0 11.4 2.1 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein DDRGK PF09756.9 CDO75702.1 - 6.4 6.3 17.3 4e+02 0.5 0.0 2.4 2 1 0 2 2 2 0 DDRGK domain DUF5437 PF17505.2 CDO75703.1 - 0.89 9.6 6.8 0.14 12.2 2.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5437) EMC1_C PF07774.13 CDO75706.1 - 1.7e-75 253.4 0.1 2.8e-75 252.7 0.1 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CDO75706.1 - 4.4e-05 23.2 0.6 0.024 14.2 0.1 2.9 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 CDO75706.1 - 0.0002 21.1 0.2 0.0011 18.7 0.0 2.4 2 0 0 2 2 2 1 PQQ enzyme repeat UCR_hinge PF02320.16 CDO75707.1 - 1.5e-23 82.8 4.6 1.5e-23 82.8 4.6 1.6 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Brr6_like_C_C PF10104.9 CDO75707.1 - 0.038 13.8 0.3 0.047 13.5 0.2 1.3 1 1 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF3391 PF11871.8 CDO75707.1 - 3.1 8.3 6.8 3.9 8.0 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) His_Phos_2 PF00328.22 CDO75708.1 - 8e-07 28.7 0.0 0.00033 20.1 0.0 2.4 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) RNB PF00773.19 CDO75709.1 - 2.8e-95 319.4 0.0 4.1e-95 318.9 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 CDO75709.1 - 4.8e-25 88.0 0.0 1.1e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CDO75709.1 - 3.5e-22 78.2 2.4 7.7e-22 77.1 2.4 1.6 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 CDO75709.1 - 1e-15 57.5 0.0 7e-14 51.6 0.0 3.2 3 0 0 3 3 3 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CDO75709.1 - 3.3e-09 36.8 0.8 0.0002 21.4 0.0 4.1 4 0 0 4 4 4 2 Cold shock domain PIN_4 PF13638.6 CDO75709.1 - 1.9e-05 25.0 0.0 6.6e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 PIN domain Ada3 PF10198.9 CDO75709.1 - 0.009 16.2 0.1 0.019 15.1 0.1 1.4 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 OB_RNB PF08206.11 CDO75709.1 - 0.02 14.5 1.8 0.099 12.3 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain p450 PF00067.22 CDO75710.1 - 5.6e-68 229.8 0.0 6.4e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PCI PF01399.27 CDO75711.1 - 1.3e-05 25.6 0.0 4.8e-05 23.8 0.0 1.9 1 1 1 2 2 2 1 PCI domain EF-hand_9 PF14658.6 CDO75711.1 - 0.024 15.0 0.0 9.8 6.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Kelch_1 PF01344.25 CDO75712.1 - 0.045 13.3 0.3 0.1 12.2 0.3 1.5 1 0 0 1 1 1 0 Kelch motif PMSR PF01625.21 CDO75713.1 - 3.3e-61 205.9 0.3 4.1e-61 205.7 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase GPI-anchored PF10342.9 CDO75714.1 - 0.0038 18.0 0.0 0.01 16.6 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AA_permease_2 PF13520.6 CDO75715.1 - 2.7e-74 250.5 39.8 2.7e-74 250.5 39.8 1.4 1 1 1 2 2 2 1 Amino acid permease Tyr-DNA_phospho PF06087.12 CDO75716.1 - 4.2e-47 161.0 0.1 1.9e-27 96.2 0.0 2.3 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 CDO75716.1 - 0.00089 19.1 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 PLD-like domain NAD_binding_4 PF07993.12 CDO75719.1 - 1.1e-31 109.9 0.0 1.7e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CDO75719.1 - 4.7e-24 84.7 0.0 1.2e-23 83.4 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 CDO75719.1 - 2.1e-10 40.5 0.0 3.9e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CDO75719.1 - 0.0045 17.3 0.0 0.0099 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 CDO75719.1 - 0.0054 16.7 0.1 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 CDO75719.1 - 0.0062 16.0 0.0 0.06 12.7 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CDO75719.1 - 0.037 13.0 0.0 0.1 11.6 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CDO75719.1 - 0.15 11.1 0.4 1.7 7.7 0.1 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.20 CDO75719.1 - 0.18 12.0 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 CDO75719.1 - 0.21 10.7 0.1 0.45 9.6 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 CDO75721.1 - 1.6e-20 73.4 17.2 2.2e-17 63.1 21.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_UL49_2 PF04823.12 CDO75721.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Toxin_GhoT_OrtT PF10753.9 CDO75721.1 - 0.061 13.6 2.2 2 8.7 0.0 3.2 2 0 0 2 2 2 0 Toxin GhoT_OrtT Wzz PF02706.15 CDO75721.1 - 0.071 13.4 0.3 0.63 10.4 0.1 2.3 2 0 0 2 2 2 0 Chain length determinant protein DUF2207 PF09972.9 CDO75721.1 - 5 5.8 6.8 4.1 6.1 0.1 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Xpo1 PF08389.12 CDO75722.1 - 4.2e-08 33.4 0.2 0.00014 22.0 0.1 4.1 4 0 0 4 4 4 1 Exportin 1-like protein Importin_rep PF18773.1 CDO75722.1 - 4.7e-08 32.6 0.4 9.8e-08 31.6 0.4 1.5 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 CDO75722.1 - 8.1e-06 25.7 0.1 0.0002 21.2 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain OrsD PF12013.8 CDO75724.1 - 0.021 15.3 0.8 0.032 14.7 0.8 1.3 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Dimer_Tnp_hAT PF05699.14 CDO75725.1 - 0.00065 19.4 0.5 0.0014 18.4 0.5 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region OTT_1508_deam PF14441.6 CDO75726.1 - 4.7e-15 55.4 0.8 1.1e-14 54.1 0.8 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase TetR_C_28 PF17937.1 CDO75726.1 - 0.36 11.3 2.5 21 5.6 0.1 3.5 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain WD40 PF00400.32 CDO75727.1 - 2e-14 53.7 4.9 5.5e-05 23.8 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1899 PF08953.11 CDO75727.1 - 9e-06 25.5 0.1 2.7e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 CDO75727.1 - 7.3e-05 23.0 0.0 0.049 13.9 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4140 PF13600.6 CDO75727.1 - 0.052 14.0 0.2 0.11 13.0 0.2 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 CDO75727.1 - 0.067 13.0 2.6 0.14 11.9 2.6 1.4 1 0 0 1 1 1 0 Septum formation initiator DJ-1_PfpI PF01965.24 CDO75728.1 - 1.2e-37 129.3 0.0 1.5e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 CDO75728.1 - 0.003 17.2 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain BPL_N PF09825.9 CDO75728.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal ThiJ_like PF17124.5 CDO75728.1 - 0.029 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 ThiJ/PfpI family-like NUC153 PF08159.12 CDO75729.1 - 2.9e-12 46.2 0.9 6.3e-12 45.1 0.9 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 CDO75729.1 - 0.0012 19.6 0.3 9.3 7.3 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat Nop14 PF04147.12 CDO75729.1 - 0.0028 16.0 16.2 0.0039 15.5 16.2 1.1 1 0 0 1 1 1 1 Nop14-like family YqjK PF13997.6 CDO75730.1 - 0.016 15.4 0.5 0.049 13.9 0.1 2.0 2 0 0 2 2 2 0 YqjK-like protein Orai-1 PF07856.12 CDO75730.1 - 0.026 14.2 4.3 0.019 14.7 2.0 1.9 2 0 0 2 2 2 0 Mediator of CRAC channel activity SURF4 PF02077.15 CDO75731.1 - 5.8e-97 324.5 4.3 7.2e-97 324.2 4.3 1.0 1 0 0 1 1 1 1 SURF4 family HhH-GPD PF00730.25 CDO75732.1 - 3e-20 72.7 0.0 6.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 CDO75732.1 - 3.7e-09 36.5 1.7 2e-06 27.7 0.2 4.1 2 1 0 2 2 2 1 NUDIX domain HHH PF00633.23 CDO75732.1 - 0.00049 19.8 0.1 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF3827 PF12877.7 CDO75732.1 - 0.12 10.7 0.7 0.17 10.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Gti1_Pac2 PF09729.9 CDO75733.1 - 8.3e-28 97.7 0.1 3.8e-25 89.0 0.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family DUF3395 PF11875.8 CDO75734.1 - 1.1e-35 122.8 0.0 2.7e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CDO75734.1 - 4.3e-19 68.4 0.5 8.7e-19 67.4 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L29 PF00831.23 CDO75734.1 - 0.026 14.5 0.5 0.026 14.5 0.5 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein DUF155 PF02582.14 CDO75735.1 - 1.6e-24 87.0 0.1 1.8e-15 57.5 0.0 2.7 2 1 1 3 3 3 2 Uncharacterised ACR, YagE family COG1723 Hox9_act PF04617.13 CDO75735.1 - 0.066 14.0 0.2 0.066 14.0 0.2 1.6 2 0 0 2 2 2 0 Hox9 activation region MscS_porin PF12795.7 CDO75735.1 - 0.072 12.6 0.9 0.16 11.5 0.9 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain GSCFA PF08885.11 CDO75735.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 GSCFA family ADH_N PF08240.12 CDO75736.1 - 1.7e-32 111.6 2.2 2.9e-32 110.8 2.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO75736.1 - 1.2e-15 57.6 0.0 2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CDO75736.1 - 6.2e-11 42.2 0.0 9.4e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CDO75736.1 - 5.8e-06 27.4 0.0 1.1e-05 26.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 CDO75736.1 - 0.00075 18.8 0.3 0.0011 18.3 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Staph_opine_DH PF10100.9 CDO75736.1 - 0.034 12.8 0.0 0.045 12.4 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase NAD_binding_7 PF13241.6 CDO75736.1 - 0.046 14.2 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding NADH_4Fe-4S PF10589.9 CDO75736.1 - 0.13 12.4 0.5 0.31 11.1 0.5 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region AMP-binding PF00501.28 CDO75737.1 - 1.6e-78 264.2 0.0 2.6e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDO75737.1 - 8.7e-10 39.4 1.0 7.6e-09 36.4 1.0 2.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain His_Phos_2 PF00328.22 CDO75738.1 - 3e-17 63.1 0.1 4.9e-12 45.9 0.1 2.8 2 2 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) Cyt-b5 PF00173.28 CDO75739.1 - 9.8e-21 73.7 0.2 1.9e-20 72.7 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 CDO75739.1 - 2.7e-13 50.4 17.3 2.7e-13 50.4 17.3 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TMEM189_B_dmain PF10520.9 CDO75739.1 - 1.4 9.0 6.2 2.5 8.2 5.4 1.9 1 1 1 2 2 2 0 B domain of TMEM189, localisation domain Sec5 PF15469.6 CDO75740.1 - 1.6e-58 197.6 2.2 2.9e-58 196.8 0.3 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec5 CK2S PF15011.6 CDO75740.1 - 0.0079 16.1 1.1 0.04 13.8 0.1 2.6 3 0 0 3 3 3 1 Casein Kinase 2 substrate Chordopox_A13L PF05961.11 CDO75740.1 - 0.16 12.2 0.0 0.56 10.5 0.0 2.0 1 0 0 1 1 1 0 Chordopoxvirus A13L protein COG2 PF06148.11 CDO75740.1 - 0.37 10.9 2.2 2.1 8.4 0.0 2.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 CDO75740.1 - 0.57 10.8 5.9 24 5.5 0.3 4.0 4 0 0 4 4 4 0 Syntaxin 6, N-terminal AvrM-A PF18241.1 CDO75740.1 - 1.9 8.9 6.2 11 6.4 0.1 3.3 3 0 0 3 3 3 0 Flax-rust effector AvrM-A DUF2070 PF09843.9 CDO75741.1 - 2.6 6.2 5.7 3.8 5.7 5.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AMP-binding PF00501.28 CDO75744.1 - 5.7e-70 236.0 0.0 8.3e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CDO75744.1 - 1.5e-67 227.5 0.0 3e-67 226.5 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 CDO75744.1 - 1.4e-15 57.4 0.0 7.2e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.20 CDO75744.1 - 4.4e-12 45.4 0.0 1.4e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 Condensation domain Epimerase PF01370.21 CDO75744.1 - 7.3e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO75744.1 - 6e-06 25.5 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 CDO75744.1 - 6.9e-05 23.8 0.0 0.00041 21.3 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain IBR PF01485.21 CDO75745.1 - 4.2e-10 39.7 9.1 4.2e-10 39.7 9.1 1.7 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain AZUL PF16558.5 CDO75745.1 - 0.24 11.7 6.4 0.68 10.2 6.4 1.8 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2 PF00096.26 CDO75745.1 - 0.66 10.5 7.8 14 6.3 0.0 3.8 3 1 0 3 3 3 0 Zinc finger, C2H2 type DEAD PF00270.29 CDO75746.1 - 3.1e-35 121.5 0.0 6.6e-35 120.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO75746.1 - 2.2e-15 57.0 0.0 2.4e-14 53.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO75746.1 - 0.0018 18.3 0.0 0.028 14.4 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 CDO75746.1 - 0.022 13.5 0.0 0.15 10.8 0.0 2.0 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Colicin PF01024.19 CDO75746.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Colicin pore forming domain KH_1 PF00013.29 CDO75747.1 - 5.1e-10 39.0 0.2 9.4e-08 31.8 0.0 2.5 2 1 0 2 2 2 2 KH domain Trp_repressor PF01371.19 CDO75747.1 - 0.039 14.1 0.1 0.081 13.1 0.1 1.4 1 0 0 1 1 1 0 Trp repressor protein 3Beta_HSD PF01073.19 CDO75748.1 - 1.2e-27 96.6 0.0 1.1e-26 93.5 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CDO75748.1 - 4.1e-11 42.8 0.0 2.5e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CDO75748.1 - 3.4e-10 39.5 0.0 3e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 CDO75748.1 - 0.00013 22.0 0.0 0.00052 19.9 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CDO75748.1 - 0.00023 20.7 0.0 0.0011 18.4 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 CDO75748.1 - 0.00049 20.1 0.0 0.00078 19.4 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CDO75748.1 - 0.0011 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDO75748.1 - 0.015 14.5 0.0 0.041 13.0 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CTP_synth_N PF06418.14 CDO75749.1 - 3e-108 361.2 0.3 5e-108 360.4 0.3 1.4 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CDO75749.1 - 9.3e-51 172.3 0.0 1.5e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CDO75749.1 - 0.037 13.8 0.1 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 CbiA PF01656.23 CDO75749.1 - 0.045 13.8 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CDO75749.1 - 0.2 10.8 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase ADH_N PF08240.12 CDO75750.1 - 1.8e-29 101.8 0.4 4.2e-29 100.6 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO75750.1 - 2.2e-17 63.2 0.0 3.9e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CDO75750.1 - 1.6e-12 47.4 0.1 2.6e-12 46.7 0.1 1.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 CDO75750.1 - 3.2e-05 23.3 0.1 0.00011 21.6 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain ADH_zinc_N_2 PF13602.6 CDO75750.1 - 0.00026 22.0 0.0 0.00048 21.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 CDO75750.1 - 0.008 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CDO75750.1 - 0.009 16.4 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_3 PF03447.16 CDO75750.1 - 0.011 16.4 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 CDO75750.1 - 0.062 12.5 0.3 1.4 8.1 0.3 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CDO75750.1 - 0.078 13.0 0.1 0.19 11.8 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 CDO75750.1 - 0.18 12.1 0.3 0.35 11.1 0.3 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Staph_opine_DH PF10100.9 CDO75750.1 - 0.21 10.2 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase p450 PF00067.22 CDO75751.1 - 3.6e-49 167.8 0.0 1.1e-48 166.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 F-box PF00646.33 CDO75752.1 - 0.0024 17.7 1.5 0.0053 16.6 1.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO75752.1 - 0.011 15.7 1.0 0.022 14.6 1.0 1.6 1 0 0 1 1 1 0 F-box-like Cellulase PF00150.18 CDO75753.1 - 6.6e-51 173.4 0.5 8.6e-51 173.0 0.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 CDO75753.1 - 1.4e-12 47.3 7.3 1.4e-12 47.3 7.3 3.7 6 0 0 6 6 6 1 Fungal cellulose binding domain CSN5_C PF18323.1 CDO75755.1 - 1.4e-29 102.9 2.6 2.4e-29 102.1 2.6 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain JAB PF01398.21 CDO75755.1 - 6.1e-28 97.2 0.1 9.6e-28 96.5 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CDO75755.1 - 0.00045 20.0 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Oxidored-like PF09791.9 CDO75756.1 - 5.3e-18 64.4 0.6 1.1e-17 63.4 0.6 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Glyco_hydro_1 PF00232.18 CDO75757.1 - 2.6e-132 441.5 0.3 7.5e-132 440.0 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 ABC_tran PF00005.27 CDO75757.1 - 3e-07 31.0 2.2 1.1e-05 26.0 0.0 2.9 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 CDO75757.1 - 0.00014 21.5 0.2 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CDO75757.1 - 0.0002 21.9 1.7 0.017 15.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 CDO75757.1 - 0.002 17.1 3.3 0.0036 16.3 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 CDO75757.1 - 0.0039 17.1 3.5 0.0087 15.9 1.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CDO75757.1 - 0.0067 16.4 1.1 0.063 13.2 0.1 2.5 2 1 0 2 2 2 1 NACHT domain SMC_N PF02463.19 CDO75757.1 - 0.0089 15.5 0.1 0.052 13.0 0.1 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 CDO75757.1 - 0.023 14.0 1.0 0.073 12.4 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CDO75757.1 - 0.033 14.3 1.5 0.24 11.5 0.2 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 CDO75757.1 - 0.049 13.9 0.4 0.049 13.9 0.4 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 CDO75757.1 - 0.056 13.1 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CDO75757.1 - 0.063 13.6 0.2 0.81 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CDO75757.1 - 0.09 12.4 0.4 10 5.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDO75757.1 - 0.12 12.7 2.7 0.51 10.7 0.0 2.8 3 0 0 3 3 2 0 AAA ATPase domain MobB PF03205.14 CDO75757.1 - 0.12 12.3 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 CDO75757.1 - 0.13 12.4 0.9 0.34 11.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CDO75757.1 - 0.18 11.8 0.1 7.1 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CDO75757.1 - 0.19 11.8 0.5 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 CDO75757.1 - 0.23 11.4 0.4 0.47 10.3 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase AAA_18 PF13238.6 CDO75757.1 - 0.25 11.9 1.7 2.1 8.9 0.4 2.7 2 0 0 2 2 2 0 AAA domain Caldesmon PF02029.15 CDO75757.1 - 0.33 9.7 9.3 1 8.1 9.3 1.6 1 1 0 1 1 1 0 Caldesmon DUF5302 PF17227.2 CDO75757.1 - 0.33 12.0 2.5 1.1 10.3 2.5 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5302) ATPase_2 PF01637.18 CDO75757.1 - 0.45 10.4 1.9 23 4.8 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Ribosomal_L18A PF01775.17 CDO75758.1 - 2.8e-55 185.6 0.3 3.6e-55 185.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A IBR PF01485.21 CDO75759.1 - 2.2e-08 34.2 20.4 7e-06 26.2 11.1 3.0 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 CDO75759.1 - 3.6e-05 23.4 1.8 0.00017 21.2 1.8 2.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CDO75759.1 - 0.00064 20.0 3.5 0.00064 20.0 3.5 3.5 4 0 0 4 4 4 1 Ring finger domain zf-rbx1 PF12678.7 CDO75759.1 - 0.022 15.1 0.1 0.022 15.1 0.1 3.4 3 0 0 3 3 3 0 RING-H2 zinc finger domain NUDE_C PF04880.13 CDO75760.1 - 0.37 11.2 3.2 0.55 10.7 3.2 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Pro_isomerase PF00160.21 CDO75762.1 - 1.7e-47 161.6 0.2 1.9e-47 161.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AA_permease_2 PF13520.6 CDO75763.1 - 2.4e-68 230.9 21.4 1.4e-67 228.4 21.4 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDO75763.1 - 1.8e-11 43.3 16.1 1.2e-09 37.4 6.7 2.1 2 0 0 2 2 2 2 Amino acid permease HbrB PF08539.11 CDO75765.1 - 1.4e-51 174.8 0.0 2.1e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 HbrB-like OPT PF03169.15 CDO75766.1 - 8.6e-33 113.9 5.6 2.1e-31 109.3 5.6 1.9 1 1 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 CDO75767.1 - 2.4e-193 644.2 66.5 2.7e-193 644.0 66.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Nop25 PF09805.9 CDO75768.1 - 4.4e-20 72.5 27.3 4.4e-20 72.5 27.3 3.2 2 2 0 2 2 2 1 Nucleolar protein 12 (25kDa) VD10_N PF08476.10 CDO75768.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Viral D10 N-terminal DUF778 PF05608.12 CDO75768.1 - 8.2 6.7 7.3 2.5e+02 1.9 7.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Methyltransf_16 PF10294.9 CDO75769.1 - 7e-12 45.4 0.0 3.2e-07 30.3 0.0 2.3 1 1 0 2 2 2 2 Lysine methyltransferase V-SNARE_C PF12352.8 CDO75770.1 - 1.6e-17 63.5 0.3 4.7e-17 62.0 0.3 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CDO75770.1 - 4.2e-08 33.0 0.5 3e-07 30.3 0.0 2.3 2 1 1 3 3 3 1 Sec20 BAR_2 PF10455.9 CDO75770.1 - 0.015 14.4 0.1 0.018 14.2 0.1 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking FadA PF09403.10 CDO75770.1 - 0.07 13.6 3.8 0.11 13.0 3.8 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Plasmid_RAQPRD PF09686.10 CDO75770.1 - 0.1 12.8 2.6 0.31 11.3 1.1 2.2 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TPR_MLP1_2 PF07926.12 CDO75770.1 - 0.88 9.6 5.6 1.6 8.8 4.1 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein COesterase PF00135.28 CDO75771.1 - 4.3e-78 263.4 0.0 7.5e-77 259.3 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDO75771.1 - 0.006 16.5 0.1 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDO75771.1 - 0.013 15.0 0.9 0.036 13.5 0.9 1.6 1 1 1 2 2 2 0 Prolyl oligopeptidase family Myb_DNA-bind_4 PF13837.6 CDO75773.1 - 6.1e-09 36.1 0.2 1.2e-08 35.3 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CDO75773.1 - 1.1e-08 35.9 0.1 1.8e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO75773.1 - 0.0009 19.3 0.0 0.0035 17.4 0.0 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CDO75773.1 - 0.01 16.0 0.3 0.021 15.0 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myc_N PF01056.18 CDO75773.1 - 0.021 14.7 0.8 0.034 14.0 0.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region TAP42 PF04177.12 CDO75773.1 - 0.043 13.0 0.7 0.067 12.3 0.7 1.3 1 0 0 1 1 1 0 TAP42-like family TAL_effector PF03377.13 CDO75773.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 TAL effector repeat Myb_DNA-bind_6 PF13921.6 CDO75773.1 - 0.11 12.7 0.2 0.27 11.5 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain RRN3 PF05327.11 CDO75773.1 - 0.26 9.8 2.5 0.33 9.5 2.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 CDO75773.1 - 4.3 7.8 9.8 8.9 6.8 9.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RVT_2 PF07727.14 CDO75774.1 - 2e-69 233.9 0.0 3.1e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO75774.1 - 1.1e-16 61.1 0.5 1.3e-15 57.6 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO75774.1 - 1.9e-13 50.3 0.0 3.5e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO75774.1 - 2.1e-11 43.5 0.0 5.9e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 CDO75774.1 - 0.00015 21.6 1.9 0.00059 19.8 1.9 2.1 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CDO75774.1 - 0.0056 16.5 1.9 0.0056 16.5 1.9 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDO75774.1 - 0.1 12.4 1.9 0.24 11.2 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 CDO75774.1 - 0.11 12.9 0.2 0.37 11.2 0.2 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G CEP76-C2 PF15627.6 CDO75774.1 - 0.13 11.9 0.1 0.44 10.1 0.1 1.9 2 0 0 2 2 2 0 CEP76 C2 domain KDZ PF18758.1 CDO75775.1 - 8e-78 261.1 0.0 1.2e-77 260.5 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 CDO75775.1 - 0.00013 22.0 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 CDO75776.1 - 0.0092 16.3 0.1 0.97 9.8 0.0 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin Phasin PF05597.11 CDO75777.1 - 0.0048 16.9 0.8 0.0099 15.9 0.8 1.5 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) HMG_box_2 PF09011.10 CDO75777.1 - 0.012 16.1 0.3 0.035 14.7 0.3 1.8 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.19 CDO75777.1 - 0.014 15.8 1.7 0.14 12.6 1.7 2.4 1 1 0 1 1 1 0 HMG (high mobility group) box Rad60-SLD PF11976.8 CDO75778.1 - 0.00018 21.3 0.0 0.00044 20.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDO75778.1 - 0.057 13.2 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin family Voldacs PF03517.13 CDO75778.1 - 0.97 9.5 3.9 1.9 8.6 1.3 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling DUF659 PF04937.15 CDO75779.1 - 2.2e-08 34.1 0.1 4.2e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3306 PF11748.8 CDO75779.1 - 2.6 8.9 6.3 0.49 11.3 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) WD40 PF00400.32 CDO75780.1 - 2.3e-35 120.0 28.2 1.6e-06 28.7 0.0 10.9 11 1 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75780.1 - 1e-16 61.0 2.6 0.051 13.9 0.1 6.7 4 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO75780.1 - 1.8e-05 23.9 2.2 1.1 8.2 0.0 5.1 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CDO75780.1 - 7.7e-05 21.4 0.1 0.011 14.3 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain NACHT PF05729.12 CDO75780.1 - 0.00021 21.2 0.0 0.00071 19.5 0.0 1.9 1 1 0 1 1 1 1 NACHT domain eIF2A PF08662.11 CDO75780.1 - 0.0053 16.7 0.1 2.2 8.1 0.0 3.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.6 CDO75780.1 - 0.0058 17.0 2.5 0.0093 16.4 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain WD40_like PF17005.5 CDO75780.1 - 0.0065 15.8 0.0 2.3 7.5 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain AAA_22 PF13401.6 CDO75780.1 - 0.19 12.0 0.0 0.45 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain HTH_IclR PF09339.10 CDO75780.1 - 0.52 10.1 2.6 5.8 6.8 0.1 3.3 3 0 0 3 3 3 0 IclR helix-turn-helix domain Nup160 PF11715.8 CDO75780.1 - 2.8 6.5 6.9 0.43 9.2 0.6 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Plavaka PF18759.1 CDO75782.1 - 1.6e-115 385.8 0.1 2.1e-115 385.4 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 CDO75783.1 - 2.8e-116 388.3 0.0 5.3e-116 387.4 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase SAD_SRA PF02182.17 CDO75784.1 - 9.8e-26 90.3 0.2 2.4e-21 76.1 0.0 2.3 2 0 0 2 2 2 2 SAD/SRA domain UDG PF03167.19 CDO75787.1 - 1.3e-15 57.7 0.0 3.3e-15 56.4 0.0 1.7 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily bZIP_1 PF00170.21 CDO75788.1 - 2.3e-05 24.4 4.6 3.8e-05 23.7 4.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CDO75788.1 - 0.002 18.2 2.4 0.0035 17.4 2.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.13 CDO75788.1 - 0.014 14.6 0.5 0.018 14.3 0.5 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region ABC_tran_CTD PF16326.5 CDO75788.1 - 0.07 13.4 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain BMFP PF04380.13 CDO75788.1 - 0.11 13.0 3.9 0.17 12.4 3.9 1.3 1 0 0 1 1 1 0 Membrane fusogenic activity TSC22 PF01166.18 CDO75788.1 - 0.12 12.7 0.4 0.21 11.9 0.4 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family WD40_alt PF14077.6 CDO75788.1 - 0.13 12.1 0.3 0.24 11.3 0.3 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif Nnf1 PF03980.14 CDO75788.1 - 0.19 12.1 2.6 0.17 12.3 1.1 1.6 2 0 0 2 2 2 0 Nnf1 PMI_typeI PF01238.21 CDO75789.1 - 1.2e-58 199.1 0.0 9.3e-34 117.2 0.0 2.1 2 0 0 2 2 2 2 Phosphomannose isomerase type I Cupin_2 PF07883.11 CDO75789.1 - 0.003 17.3 0.1 0.2 11.4 0.1 2.5 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 CDO75789.1 - 0.024 14.3 0.1 0.098 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 CDO75789.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 CDO75789.1 - 0.15 11.9 0.0 0.65 9.9 0.0 2.0 3 0 0 3 3 3 0 AraC-like ligand binding domain Abhydrolase_1 PF00561.20 CDO75790.1 - 1e-32 113.8 0.0 1.5e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO75790.1 - 1e-10 41.3 0.0 4.5e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO75790.1 - 1.1e-10 42.6 0.1 1.6e-10 42.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CDO75790.1 - 0.00095 18.7 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FA_hydroxylase PF04116.13 CDO75791.1 - 4.9e-20 72.2 23.9 4.9e-20 72.2 23.9 2.5 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily TatC PF00902.18 CDO75791.1 - 0.32 10.8 6.3 1.5 8.6 1.1 2.4 1 1 1 2 2 2 0 Sec-independent protein translocase protein (TatC) WD40 PF00400.32 CDO75792.1 - 4.3e-17 62.2 9.5 0.00069 20.4 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75792.1 - 3.1e-09 37.0 0.0 4.5e-06 26.9 0.0 4.5 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDO75792.1 - 0.00055 19.3 0.0 0.032 13.6 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain eIF2A PF08662.11 CDO75792.1 - 0.0029 17.5 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CDO75792.1 - 0.0087 15.1 0.1 5.4 5.9 0.0 3.0 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF348 PF03990.14 CDO75793.1 - 0.14 11.9 1.1 0.34 10.7 0.2 1.9 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain SIR2 PF02146.17 CDO75794.1 - 6.9e-31 107.5 0.0 1.7e-21 76.9 0.0 2.4 2 0 0 2 2 2 2 Sir2 family Zn-ribbon_8 PF09723.10 CDO75794.1 - 0.16 12.1 0.6 0.34 11.0 0.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Pol_alpha_B_N PF08418.10 CDO75794.1 - 5.2 7.0 17.4 0.029 14.3 7.8 2.1 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal CDC45 PF02724.14 CDO75794.1 - 6.2 5.0 7.2 9 4.4 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 CDO75794.1 - 8.6 6.2 12.9 16 5.3 12.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal p450 PF00067.22 CDO75795.1 - 2.1e-34 119.1 0.0 3.6e-34 118.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DSS1_SEM1 PF05160.13 CDO75796.1 - 1.5e-23 82.6 10.3 2.1e-23 82.1 10.3 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Sugar_tr PF00083.24 CDO75797.1 - 2.1e-31 109.3 21.7 3e-20 72.5 6.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDO75797.1 - 5.4e-18 65.0 35.5 5.4e-18 65.0 35.5 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Herpes_glycop PF01528.16 CDO75797.1 - 0.63 8.8 5.4 4.2 6.1 1.0 2.3 2 0 0 2 2 2 0 Herpesvirus glycoprotein M TFIIF_beta PF02270.15 CDO75798.1 - 2.8e-23 81.8 0.2 4.4e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 CDO75798.1 - 4.3e-11 43.6 0.0 6.3e-10 39.9 0.0 2.4 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 CDO75798.1 - 0.0015 19.3 0.1 0.003 18.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain BLF1 PF17752.1 CDO75798.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Burkholderia lethal factor 1 adh_short PF00106.25 CDO75799.1 - 2.6e-06 27.0 0.1 3.4e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO75799.1 - 0.007 15.9 0.1 0.0081 15.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_1 PF00561.20 CDO75800.1 - 1.5e-45 155.9 0.0 3e-45 154.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO75800.1 - 0.007 17.0 9.9 0.022 15.4 9.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Terpene_synth_C PF03936.16 CDO75801.1 - 0.0096 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF659 PF04937.15 CDO75802.1 - 3.3e-09 36.8 0.2 6.3e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3306 PF11748.8 CDO75802.1 - 0.72 10.7 5.4 0.13 13.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) RVT_2 PF07727.14 CDO75804.1 - 1.5e-55 188.5 0.0 7.2e-50 169.9 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.6 CDO75804.1 - 6e-05 22.8 0.3 0.00017 21.4 0.3 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain Transposase_21 PF02992.14 CDO75804.1 - 0.045 13.0 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Transposase family tnp2 Retrotran_gag_2 PF14223.6 CDO75804.1 - 0.06 13.0 3.2 0.04 13.6 0.5 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 CDO75804.1 - 0.24 11.1 0.8 0.56 10.0 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3275 PF11679.8 CDO75804.1 - 4.3 7.3 5.2 12 5.9 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Chromo PF00385.24 CDO75805.1 - 1.4e-07 31.3 0.1 2.2e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RP-C_C PF11800.8 CDO75806.1 - 0.072 13.2 13.7 0.75 9.9 5.4 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Adaptin_binding PF10199.9 CDO75806.1 - 1.1 9.8 14.9 9.3 6.9 6.6 2.9 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4770 PF15994.5 CDO75806.1 - 1.9 8.7 4.6 3.6 7.8 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF3708 PF12501.8 CDO75806.1 - 3.8 7.3 5.1 0.37 10.5 0.2 1.7 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter CENP-Q PF13094.6 CDO75806.1 - 6.8 6.9 28.0 0.25 11.5 7.3 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Coilin_N PF15862.5 CDO75806.1 - 8.1 6.2 12.5 0.55 10.0 7.2 1.8 2 1 0 2 2 2 0 Coilin N-terminus DDE_3 PF13358.6 CDO75807.1 - 0.00028 20.6 0.0 0.00038 20.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Sugar_tr PF00083.24 CDO75808.1 - 4.2e-129 431.3 20.3 4.8e-129 431.2 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO75808.1 - 1.3e-21 77.0 38.2 2.5e-17 62.9 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TFIIF_alpha PF05793.12 CDO75809.1 - 8.9 4.8 12.9 13 4.2 12.9 1.3 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Transposase_21 PF02992.14 CDO75810.1 - 1.4e-16 60.4 0.2 1.4e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 Transposase family tnp2 FPP PF05911.11 CDO75810.1 - 0.0023 16.2 6.2 0.0034 15.7 6.2 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Laminin_I PF06008.14 CDO75810.1 - 0.003 17.3 1.9 0.003 17.3 1.9 1.8 1 1 1 2 2 2 1 Laminin Domain I DUF4218 PF13960.6 CDO75810.1 - 0.027 14.1 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF1258 PF06869.12 CDO75810.1 - 0.03 13.8 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DUF1664 PF07889.12 CDO75810.1 - 0.031 14.3 9.0 0.22 11.6 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Med8 PF10232.9 CDO75810.1 - 0.039 13.6 0.1 0.095 12.3 0.1 1.6 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Baculo_PEP_C PF04513.12 CDO75810.1 - 0.053 13.6 2.1 0.14 12.2 0.1 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 CDO75810.1 - 0.088 12.8 10.7 0.28 11.2 3.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 CDO75810.1 - 0.092 13.2 0.2 3.4 8.2 0.1 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SHE3 PF17078.5 CDO75810.1 - 0.15 11.7 4.3 0.61 9.8 4.3 1.9 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 AAA_13 PF13166.6 CDO75810.1 - 0.16 10.6 2.8 0.26 9.9 2.8 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 CDO75810.1 - 0.17 10.7 9.2 0.32 9.8 9.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4618 PF15397.6 CDO75810.1 - 0.29 10.5 4.3 0.58 9.5 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4200 PF13863.6 CDO75810.1 - 0.29 11.5 4.8 2.3 8.7 0.1 2.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) DUF2968 PF11180.8 CDO75810.1 - 1.1 8.9 4.9 0.8 9.3 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Hemerythrin PF01814.23 CDO75810.1 - 2.2 8.9 7.2 0.32 11.6 2.3 2.3 2 0 0 2 2 1 0 Hemerythrin HHE cation binding domain Nup54 PF13874.6 CDO75810.1 - 6.2 6.9 6.4 6.2 6.9 3.5 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Cnd2 PF05786.14 CDO75813.1 - 1.4e-177 592.8 3.4 4.3e-177 591.2 3.4 1.6 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CDO75813.1 - 0.084 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Leo1 PF04004.13 CDO75816.1 - 4e-51 173.2 0.0 4e-51 173.2 0.0 2.5 3 1 0 3 3 3 1 Leo1-like protein Atx10homo_assoc PF09759.9 CDO75817.1 - 5.7e-27 93.6 0.0 9.5e-27 92.9 0.0 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain NUDIX PF00293.28 CDO75819.1 - 2.4e-10 40.5 0.0 6.1e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain BRAP2 PF07576.12 CDO75820.1 - 7.7e-23 80.6 0.0 1.4e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CDO75820.1 - 2.8e-19 69.2 3.7 7.3e-19 67.9 3.7 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CDO75820.1 - 1.6e-08 34.7 8.6 1.6e-08 34.7 8.6 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CDO75820.1 - 1.4e-06 28.3 3.8 4.7e-06 26.5 4.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CDO75820.1 - 5.8e-06 26.0 3.7 1.5e-05 24.6 3.7 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CDO75820.1 - 1e-05 25.7 5.5 2.5e-05 24.5 5.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CDO75820.1 - 1e-05 25.3 8.6 1e-05 25.3 8.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO75820.1 - 4.6e-05 23.2 6.6 9.8e-05 22.2 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CDO75820.1 - 0.00041 20.4 0.7 0.00079 19.4 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CDO75820.1 - 0.00059 19.6 6.3 0.00059 19.6 6.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO75820.1 - 0.00099 19.0 6.1 0.00099 19.0 6.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain TerY_C PF15616.6 CDO75820.1 - 0.029 14.5 6.1 0.11 12.6 0.3 2.4 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_4 PF14570.6 CDO75820.1 - 0.047 13.5 5.9 0.1 12.4 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 CDO75820.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGAP_C PF03836.15 CDO75820.1 - 0.23 11.6 7.7 0.39 10.9 0.8 2.3 1 1 1 2 2 2 0 RasGAP C-terminus FapA PF03961.13 CDO75820.1 - 0.44 9.1 6.6 0.75 8.3 6.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A CorA PF01544.18 CDO75820.1 - 0.51 9.6 11.1 0.79 9.0 11.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4407 PF14362.6 CDO75820.1 - 0.93 8.8 15.2 1.8 7.9 15.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ArfGap PF01412.18 CDO75820.1 - 1.1 9.4 3.7 0.32 11.1 0.3 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf SPX PF03105.19 CDO75820.1 - 1.3 8.8 23.3 0.11 12.4 12.3 2.3 2 0 0 2 2 2 0 SPX domain zf-C3HC4_4 PF15227.6 CDO75820.1 - 1.8 8.8 6.0 7.2 6.9 6.1 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING AAA_13 PF13166.6 CDO75820.1 - 4 6.0 12.6 6.6 5.2 12.6 1.2 1 0 0 1 1 1 0 AAA domain Prok-RING_4 PF14447.6 CDO75820.1 - 6.2 6.8 20.4 1.4 8.9 11.2 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Atg14 PF10186.9 CDO75820.1 - 10 5.1 14.1 23 3.9 14.1 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DNA_pol_B PF00136.21 CDO75821.1 - 5.9e-145 483.5 0.1 7.9e-145 483.1 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CDO75821.1 - 3.3e-73 246.7 0.0 5e-73 246.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CDO75821.1 - 3e-18 66.0 6.5 6.7e-18 64.9 6.5 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CDO75821.1 - 0.0033 16.3 0.4 0.022 13.6 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 CDO75821.1 - 0.0034 17.1 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_A_exo1 PF01612.20 CDO75821.1 - 0.088 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 3'-5' exonuclease C1_1 PF00130.22 CDO75821.1 - 2.3 8.2 4.4 9.1 6.3 4.4 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) bVLRF1 PF18826.1 CDO75822.1 - 2.6e-63 212.4 0.0 4.1e-63 211.7 0.0 1.3 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_2 PF12796.7 CDO75822.1 - 0.012 16.1 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CDO75822.1 - 0.03 14.6 0.0 0.094 13.1 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDO75822.1 - 0.031 14.9 0.0 0.069 13.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDO75822.1 - 0.033 14.7 0.0 0.11 13.1 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat PMM PF03332.13 CDO75823.1 - 4.1e-107 357.0 0.1 4.8e-107 356.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Actin PF00022.19 CDO75825.1 - 7.1e-31 107.2 0.0 4.8e-30 104.5 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CDO75825.1 - 0.0084 15.0 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Ribosomal_L7Ae PF01248.26 CDO75826.1 - 8.7e-23 79.9 0.0 1e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NIR_SIR PF01077.22 CDO75827.1 - 4.9e-46 156.1 0.0 7.1e-41 139.4 0.0 2.6 2 1 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 CDO75827.1 - 3.8e-34 116.3 0.1 4.7e-16 58.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 CDO75827.1 - 2.4e-31 108.9 0.0 4.1e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 CDO75827.1 - 0.01 15.6 0.5 0.031 14.0 0.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.7 CDO75827.1 - 0.018 15.3 0.0 0.052 13.8 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain Aminotran_5 PF00266.19 CDO75828.1 - 1.3e-18 67.1 0.0 1.1e-16 60.8 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V WD40 PF00400.32 CDO75829.1 - 3.2e-10 40.4 12.2 0.73 10.8 1.2 7.5 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75829.1 - 0.035 14.4 0.0 1.1 9.5 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain YHYH PF14240.6 CDO75829.1 - 0.084 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 YHYH protein Dynein_IC2 PF11540.8 CDO75829.1 - 0.14 12.1 0.1 0.43 10.6 0.1 1.8 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 HAND PF09110.11 CDO75829.1 - 1.5 9.6 6.5 3.1 8.6 6.5 1.4 1 0 0 1 1 1 0 HAND tRNA_int_endo PF01974.17 CDO75830.1 - 1.9e-17 63.1 1.4 1.1e-16 60.6 1.4 2.1 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 CDO75830.1 - 0.0014 18.2 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Nop25 PF09805.9 CDO75830.1 - 0.076 13.5 2.0 0.16 12.5 2.0 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SAC3_GANP PF03399.16 CDO75831.1 - 4.3e-22 78.8 3.3 1.1e-21 77.4 3.3 1.6 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CDO75831.1 - 1.5e-08 34.8 0.1 4e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Cytochrom_C1 PF02167.15 CDO75832.1 - 2.2e-97 325.1 0.0 2.7e-97 324.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CDO75832.1 - 0.0011 19.2 0.0 0.0026 18.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CDO75832.1 - 0.014 16.5 0.2 0.047 14.8 0.1 2.0 2 1 0 2 2 2 0 Cytochrome c Tim17 PF02466.19 CDO75833.1 - 2.4e-25 89.1 6.1 3.2e-25 88.7 6.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HET PF06985.11 CDO75834.1 - 2.2e-13 50.8 5.2 2.8e-11 43.9 0.4 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 CDO75835.1 - 1.4e-129 432.9 19.1 1.6e-129 432.7 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO75835.1 - 1e-22 80.6 49.1 8.8e-22 77.5 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dak1 PF02733.17 CDO75836.1 - 6.9e-87 291.2 0.1 9.4e-47 159.4 0.4 2.1 1 1 1 2 2 2 2 Dak1 domain Dak2 PF02734.17 CDO75836.1 - 1.4e-18 67.4 0.7 1.7e-11 44.3 0.3 2.4 2 0 0 2 2 2 2 DAK2 domain UCH PF00443.29 CDO75837.1 - 9e-69 231.8 0.0 1.4e-68 231.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CDO75837.1 - 2.2e-16 60.2 0.1 6.8e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 DUSP domain DUF1712 PF08217.11 CDO75837.1 - 3.6e-15 55.5 0.0 5.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) UCH_1 PF13423.6 CDO75837.1 - 5.1e-12 46.0 0.0 3.5e-05 23.5 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CDO75837.1 - 0.013 15.2 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal DUF2471 PF10616.9 CDO75837.1 - 0.036 14.6 0.1 20 5.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2471) zf-CCCH PF00642.24 CDO75838.1 - 3.8e-06 26.7 19.7 0.14 12.1 1.4 5.6 6 0 0 6 6 6 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CDO75838.1 - 0.0028 17.8 9.9 0.4 10.9 3.2 3.3 1 1 2 3 3 3 3 Zinc-finger containing family zf_CCCH_4 PF18345.1 CDO75838.1 - 0.0035 17.4 19.9 7 6.9 1.2 5.9 5 1 0 5 5 5 4 Zinc finger domain MAM33 PF02330.16 CDO75838.1 - 1.1 9.1 9.7 1.8 8.4 9.7 1.2 1 0 0 1 1 1 0 Mitochondrial glycoprotein SDA1 PF05285.12 CDO75838.1 - 2.6 7.4 14.5 3.2 7.1 14.5 1.1 1 0 0 1 1 1 0 SDA1 Ribosomal_L37ae PF01780.19 CDO75839.1 - 5.8e-42 141.7 10.8 6.5e-42 141.5 10.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 CDO75839.1 - 0.00052 20.1 1.6 0.00072 19.6 1.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CDO75839.1 - 0.0032 17.4 2.0 0.0055 16.7 2.0 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.15 CDO75839.1 - 0.008 16.2 5.5 0.31 11.1 0.6 2.2 1 1 1 2 2 2 2 BED zinc finger zf-FCS PF06467.14 CDO75839.1 - 0.036 14.0 2.6 0.95 9.5 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.6 CDO75839.1 - 0.071 12.5 1.5 7.9 6.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF2175 PF09943.9 CDO75839.1 - 0.072 13.4 0.8 3.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-Sec23_Sec24 PF04810.15 CDO75839.1 - 0.41 10.7 6.3 2.9 8.0 0.3 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger C1_2 PF03107.16 CDO75839.1 - 0.45 10.9 3.1 1.2 9.5 3.1 1.7 1 1 0 1 1 1 0 C1 domain zf-H2C2_2 PF13465.6 CDO75839.1 - 0.9 10.1 6.4 1.1 9.8 0.9 2.2 1 1 1 2 2 2 0 Zinc-finger double domain baeRF_family12 PF18856.1 CDO75841.1 - 0.023 15.3 8.5 0.027 15.0 8.5 1.1 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 SelP_N PF04592.14 CDO75841.1 - 0.12 11.7 14.5 0.15 11.4 14.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Herpes_LMP1 PF05297.11 CDO75841.1 - 0.24 10.6 2.1 0.28 10.4 2.1 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Zip PF02535.22 CDO75841.1 - 1.5 7.9 4.6 1.5 7.9 4.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Abhydrolase_3 PF07859.13 CDO75842.1 - 5.8e-37 127.6 0.0 3.9e-29 102.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDO75842.1 - 5e-11 42.1 0.0 1.6e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase PsiA PF06952.11 CDO75842.1 - 0.12 11.6 0.1 0.27 10.5 0.1 1.5 1 0 0 1 1 1 0 PsiA protein ECM11 PF15463.6 CDO75843.1 - 0.0011 19.5 0.1 0.0019 18.8 0.1 1.5 1 0 0 1 1 1 1 Extracellular mutant protein 11 SnAC PF14619.6 CDO75843.1 - 0.12 13.0 1.1 0.33 11.6 1.1 1.8 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex 4HBT PF03061.22 CDO75844.1 - 3.5e-10 40.1 0.0 6.5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 CDO75844.1 - 2.4e-06 28.0 0.0 3.4e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 CDO75844.1 - 0.00018 20.9 0.1 0.0034 16.7 0.5 2.0 2 0 0 2 2 2 1 Acyl-ACP thioesterase AA_permease_2 PF13520.6 CDO75845.1 - 2.8e-79 266.9 45.9 3.9e-79 266.5 45.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDO75845.1 - 3.2e-12 45.8 30.9 3.2e-12 45.8 30.9 1.6 2 0 0 2 2 2 1 Amino acid permease SUR7 PF06687.12 CDO75846.1 - 7.3e-14 51.9 12.3 1.3e-13 51.1 12.3 1.4 1 0 0 1 1 1 1 SUR7/PalI family Plavaka PF18759.1 CDO75849.1 - 4.1e-95 318.7 0.0 4.5e-54 183.9 0.2 2.4 1 1 1 2 2 2 2 Plavaka transposase RVT_1 PF00078.27 CDO75850.1 - 8.9e-24 84.2 0.0 1.6e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO75850.1 - 2e-08 34.5 0.0 3.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.6 CDO75850.1 - 7.5e-06 25.8 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 CDO75850.1 - 0.0011 19.6 0.0 0.0036 18.0 0.0 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CDO75850.1 - 0.0085 15.6 0.7 0.024 14.2 0.4 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M14 PF00246.24 CDO75851.1 - 4.7e-59 200.6 0.0 6.4e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Phytase-like PF13449.6 CDO75851.1 - 1.7e-36 126.6 0.1 2.2e-36 126.3 0.1 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase ATG13 PF10033.9 CDO75852.1 - 1.3e-41 142.9 0.0 1.7e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 13 Cupin_8 PF13621.6 CDO75853.1 - 4.5e-20 72.4 0.0 7e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 CDO75853.1 - 0.0072 16.0 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 Cupin domain Cupin_4 PF08007.12 CDO75853.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein JmjC PF02373.22 CDO75853.1 - 0.061 13.8 0.0 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 JmjC domain, hydroxylase PTR2 PF00854.21 CDO75854.1 - 2.7e-79 266.8 9.2 3.9e-79 266.3 9.2 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 CDO75854.1 - 3.1e-08 32.9 27.0 6.6e-07 28.6 25.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily GTP_EFTU PF00009.27 CDO75855.1 - 9.7e-66 221.0 0.2 1.5e-65 220.4 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CDO75855.1 - 6.1e-34 116.4 0.0 1.9e-32 111.6 0.0 2.7 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CDO75855.1 - 6.2e-22 77.4 0.0 1.4e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CDO75855.1 - 1.2e-13 50.9 0.0 3.4e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CDO75855.1 - 2.1e-13 50.4 0.0 6.7e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDO75855.1 - 0.00023 21.2 0.2 0.00056 20.0 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CDO75855.1 - 0.15 11.8 0.4 0.67 9.7 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArAE_2_N PF10337.9 CDO75856.1 - 7.3e-50 170.4 0.1 1.1e-49 169.8 0.1 1.3 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 CDO75856.1 - 1.5e-27 97.0 0.0 3.5e-25 89.2 0.0 2.4 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 DUF3959 PF13105.6 CDO75856.1 - 4 6.9 6.5 1.3 8.5 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) TAL_FSA PF00923.19 CDO75857.1 - 1.2e-96 323.5 0.0 1.3e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase GST_N_3 PF13417.6 CDO75858.1 - 5.4e-08 33.1 0.0 1.4e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO75858.1 - 2.7e-06 27.6 0.1 4.8e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDO75858.1 - 0.13 12.5 0.0 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain LRR_6 PF13516.6 CDO75859.1 - 4.8e-17 60.5 21.6 0.0014 18.5 0.1 8.9 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 CDO75859.1 - 1.4e-08 34.9 10.3 0.03 14.7 1.1 6.0 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) GAT PF03127.14 CDO75859.1 - 0.0011 19.2 0.2 0.0031 17.8 0.2 1.7 1 0 0 1 1 1 1 GAT domain LRR_1 PF00560.33 CDO75859.1 - 0.18 12.5 15.2 40 5.3 0.3 7.4 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 CDO75859.1 - 0.3 10.9 21.7 2.7 7.8 3.8 6.6 4 1 3 7 7 7 0 Leucine rich repeat LRR_9 PF14580.6 CDO75859.1 - 1.1 8.8 3.8 1.8 8.0 0.3 2.6 3 1 1 4 4 4 0 Leucine-rich repeat AhpC-TSA PF00578.21 CDO75860.1 - 7.9e-27 93.6 0.0 1.1e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDO75860.1 - 3.4e-16 59.3 0.0 5.1e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin HMG14_17 PF01101.18 CDO75860.1 - 0.0082 17.1 9.0 0.022 15.7 9.0 1.7 1 0 0 1 1 1 1 HMG14 and HMG17 AhpC-TSA_2 PF13911.6 CDO75860.1 - 0.012 15.7 0.0 0.032 14.3 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme WH1 PF00568.23 CDO75861.1 - 7.6e-26 90.2 0.0 1.1e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 CDO75861.1 - 2.2e-08 34.3 0.2 5.1e-08 33.1 0.2 1.7 1 1 0 1 1 1 1 P21-Rho-binding domain DUF2076 PF09849.9 CDO75861.1 - 0.0044 17.1 3.5 0.0044 17.1 3.5 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) WH2 PF02205.20 CDO75861.1 - 0.0056 16.5 0.1 0.0056 16.5 0.1 2.3 2 0 0 2 2 2 1 WH2 motif DCP1 PF06058.13 CDO75861.1 - 0.019 14.9 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family EF-hand_1 PF00036.32 CDO75862.1 - 4.3e-43 141.7 11.0 3.7e-10 38.6 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDO75862.1 - 2.6e-36 123.9 3.3 8.1e-19 67.8 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CDO75862.1 - 1.3e-32 111.4 10.4 1.3e-13 50.5 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CDO75862.1 - 1.1e-31 106.1 6.0 2.1e-09 36.6 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CDO75862.1 - 1.9e-28 96.6 7.7 1.5e-06 27.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CDO75862.1 - 6.9e-16 58.3 0.1 2.1e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CDO75862.1 - 9.4e-10 38.4 1.3 2.4e-05 24.2 0.2 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CDO75862.1 - 9.4e-09 35.6 0.0 0.0006 20.1 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 CDO75862.1 - 1.3e-06 28.3 0.0 0.039 14.0 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 CDO75862.1 - 1.4e-05 25.9 0.0 0.0069 17.2 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 CDO75862.1 - 7e-05 22.8 0.5 0.00022 21.2 0.1 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CDO75862.1 - 0.00026 21.1 6.2 0.022 15.0 0.9 3.0 1 1 1 2 2 2 2 Dockerin type I domain DUF1103 PF06513.11 CDO75862.1 - 0.00034 20.3 1.5 0.0004 20.1 1.5 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 CDO75862.1 - 0.0006 19.8 0.4 0.57 10.1 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 CDO75862.1 - 0.0021 18.0 0.2 0.42 10.6 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB Poly_export PF02563.16 CDO75862.1 - 0.0023 18.1 0.1 0.58 10.4 0.0 3.0 1 1 2 3 3 3 1 Polysaccharide biosynthesis/export protein EF-hand_14 PF17959.1 CDO75862.1 - 0.0089 16.4 0.1 5.3 7.5 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain RNA_pol_Rpb4 PF03874.16 CDO75862.1 - 0.0099 16.2 0.9 4 7.8 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF4497 PF14924.6 CDO75862.1 - 0.011 16.1 0.0 0.97 9.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) SurA_N_2 PF13623.6 CDO75862.1 - 0.015 15.1 0.6 0.9 9.4 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 CDO75862.1 - 0.019 15.1 0.5 0.34 11.1 0.1 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF5580 PF17743.1 CDO75862.1 - 0.021 13.4 0.0 0.021 13.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SapB_1 PF05184.15 CDO75862.1 - 0.065 13.3 0.3 25 5.0 0.0 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF1811 PF08838.10 CDO75862.1 - 0.078 13.2 0.0 21 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) Fe_hyd_lg_C PF02906.14 CDO75862.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Proteasome PF00227.26 CDO75863.1 - 4.8e-36 124.0 0.0 6e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Rad60-SLD PF11976.8 CDO75864.1 - 0.00015 21.5 0.0 0.00042 20.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDO75864.1 - 0.054 13.3 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin family Voldacs PF03517.13 CDO75864.1 - 0.92 9.6 3.9 1.8 8.7 1.3 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Myb_DNA-bind_3 PF12776.7 CDO75865.1 - 2.2e-09 38.1 0.1 4e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO75865.1 - 4e-09 36.7 0.1 9.7e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO75865.1 - 0.00076 19.5 0.1 0.0031 17.5 0.1 2.0 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myc_N PF01056.18 CDO75865.1 - 0.0049 16.8 0.9 0.0078 16.2 0.9 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Myb_DNA-binding PF00249.31 CDO75865.1 - 0.0075 16.4 0.3 0.017 15.3 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain CENP-B_dimeris PF09026.10 CDO75865.1 - 0.045 14.1 2.8 0.099 13.0 2.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TAL_effector PF03377.13 CDO75865.1 - 0.064 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 TAL effector repeat Myb_DNA-bind_6 PF13921.6 CDO75865.1 - 0.075 13.3 0.2 0.22 11.8 0.2 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4611 PF15387.6 CDO75865.1 - 0.08 13.2 2.8 0.21 11.8 2.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 CDO75865.1 - 0.09 13.2 3.5 0.33 11.3 2.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_Tnp_4 PF13359.6 CDO75866.1 - 3.4e-23 82.1 0.0 4.9e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO75866.1 - 3.1e-06 27.0 0.0 2e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO75866.1 - 1.5e-05 24.7 0.0 0.00013 21.6 0.1 2.0 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO75866.1 - 0.00016 21.9 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain UVR PF02151.19 CDO75866.1 - 0.36 10.6 2.3 0.73 9.7 2.3 1.4 1 0 0 1 1 1 0 UvrB/uvrC motif Myb_DNA-bind_3 PF12776.7 CDO75867.1 - 4e-09 37.4 0.1 6.2e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO75867.1 - 4.4e-09 36.6 0.1 8.2e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO75867.1 - 0.0008 19.4 0.1 0.0028 17.7 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CDO75867.1 - 0.031 14.5 0.3 0.07 13.3 0.3 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain TAL_effector PF03377.13 CDO75867.1 - 0.072 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 TAL effector repeat CCDC168_N PF15804.5 CDO75867.1 - 0.5 10.2 4.1 0.29 11.0 0.2 2.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 168 CENP-B_dimeris PF09026.10 CDO75867.1 - 0.72 10.3 7.0 1.5 9.2 7.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4939 PF16297.5 CDO75868.1 - 1.5e-11 44.2 0.0 2.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 CDO75868.1 - 0.04 14.2 0.0 0.074 13.3 0.0 1.5 2 0 0 2 2 2 0 Retrotransposon gag protein RTA1 PF04479.13 CDO75869.1 - 7.9e-59 198.7 6.1 1e-58 198.4 6.1 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3169 PF11368.8 CDO75869.1 - 0.025 14.1 3.9 0.055 13.0 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF3339 PF11820.8 CDO75869.1 - 9.1 6.6 8.1 18 5.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3339) NUDIX PF00293.28 CDO75870.1 - 2.7e-06 27.5 0.0 8e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain PIF1 PF05970.14 CDO75871.1 - 7.4e-35 120.8 0.0 4.2e-15 55.8 0.1 3.1 2 1 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CDO75871.1 - 2.1e-08 34.1 0.0 0.00045 20.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Herpes_Helicase PF02689.14 CDO75871.1 - 0.00032 18.8 0.0 0.0007 17.7 0.0 1.5 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 CDO75871.1 - 0.00066 19.4 0.0 0.0026 17.5 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 CDO75871.1 - 0.0015 18.9 0.1 0.0041 17.5 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 CDO75871.1 - 0.0045 16.5 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_7 PF12775.7 CDO75871.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 CDO75871.1 - 0.032 14.0 0.8 4.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 CDO75871.1 - 0.074 13.1 0.0 0.3 11.2 0.0 2.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase T2SSE PF00437.20 CDO75871.1 - 0.083 11.9 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 CDO75871.1 - 0.092 13.3 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CDO75871.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain p450 PF00067.22 CDO75872.1 - 3.7e-58 197.4 0.0 9e-58 196.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 APH PF01636.23 CDO75873.1 - 0.0091 15.9 0.0 0.0091 15.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CDO75873.1 - 0.041 12.7 0.0 0.049 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) CPP1-like PF11833.8 CDO75874.1 - 6.8 6.3 7.0 2.1 8.0 4.1 1.6 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Prp19 PF08606.11 CDO75875.1 - 1.9e-32 111.0 4.1 1.9e-32 111.0 4.1 1.8 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.32 CDO75875.1 - 7.1e-10 39.3 0.3 0.14 13.1 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75875.1 - 6.9e-09 35.9 0.0 0.00014 22.1 0.0 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 CDO75875.1 - 2.4e-06 27.6 0.0 9.4e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 CDO75875.1 - 1.9e-05 24.4 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Frtz PF11768.8 CDO75875.1 - 0.00036 19.0 0.0 0.00076 17.9 0.0 1.4 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF4073 PF13285.6 CDO75875.1 - 0.0016 18.1 0.0 0.029 14.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4073) zf-NOSIP PF15906.5 CDO75875.1 - 0.0047 17.0 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 CDO75875.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger SGTA_dimer PF16546.5 CDO75876.1 - 2e-28 98.0 0.4 3.4e-28 97.2 0.4 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 CDO75876.1 - 7e-26 88.9 1.6 1e-09 37.8 0.1 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CDO75876.1 - 2.5e-21 74.0 4.7 1.1e-08 34.5 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CDO75876.1 - 2.4e-19 68.7 6.0 4.9e-09 35.7 1.8 3.4 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 CDO75876.1 - 1.2e-18 65.6 1.7 1.3e-07 31.2 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDO75876.1 - 9.4e-15 53.9 0.5 0.00014 22.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CDO75876.1 - 4.7e-13 48.8 0.6 1.1e-05 25.8 0.1 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDO75876.1 - 1.6e-10 41.5 4.7 8.6e-06 26.3 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO75876.1 - 7.3e-10 38.2 0.4 0.00023 21.0 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CDO75876.1 - 4.3e-08 33.3 3.0 0.0056 16.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CDO75876.1 - 1.5e-07 31.0 3.0 0.086 12.7 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO75876.1 - 8e-07 29.5 1.1 0.003 18.0 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDO75876.1 - 2.8e-05 24.2 0.2 0.3 11.3 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO75876.1 - 0.00031 20.9 1.1 0.011 16.0 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 STI1 PF17830.1 CDO75876.1 - 0.00061 19.7 12.8 0.076 13.0 2.2 3.4 2 1 1 3 3 3 2 STI1 domain TPR_6 PF13174.6 CDO75876.1 - 0.00094 19.7 0.5 0.37 11.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDO75876.1 - 0.0072 16.4 0.3 0.11 12.6 0.0 2.6 3 0 0 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 CDO75876.1 - 0.0074 15.5 0.5 0.96 8.6 0.3 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TRAPPC9-Trs120 PF08626.11 CDO75876.1 - 0.008 13.6 0.0 0.01 13.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit BTAD PF03704.17 CDO75876.1 - 0.047 14.1 0.5 1.6 9.1 0.1 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain NARP1 PF12569.8 CDO75876.1 - 0.051 12.5 1.6 0.29 10.0 0.1 1.8 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 Spc7 PF08317.11 CDO75877.1 - 8.5e-69 231.8 3.1 5.8e-48 163.4 0.0 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein Spc7_C2 PF15577.6 CDO75877.1 - 0.00021 21.3 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 PspA_IM30 PF04012.12 CDO75877.1 - 0.0074 15.9 5.1 0.017 14.7 5.1 1.5 1 0 0 1 1 1 1 PspA/IM30 family SOUL PF04832.12 CDO75877.1 - 0.028 14.6 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 SOUL heme-binding protein PadR PF03551.14 CDO75877.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Seryl_tRNA_N PF02403.22 CDO75877.1 - 0.61 10.3 3.5 1.8 8.8 3.5 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 CDO75877.1 - 4 6.4 5.2 0.95 8.5 1.5 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Kinesin PF00225.23 CDO75878.1 - 2.1e-82 276.7 0.0 1.2e-81 274.3 0.0 2.0 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDO75878.1 - 2e-17 63.5 0.0 1.4e-13 51.0 0.0 2.9 3 0 0 3 3 3 2 Microtubule binding Mo25 PF08569.11 CDO75879.1 - 0.15 11.4 2.6 0.23 10.8 2.6 1.2 1 0 0 1 1 1 0 Mo25-like Atg14 PF10186.9 CDO75879.1 - 1.7 7.6 20.0 0.059 12.4 9.9 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2316 PF10078.9 CDO75879.1 - 2 8.7 4.2 3.8 7.8 2.6 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) LMBR1 PF04791.16 CDO75879.1 - 2.2 7.1 3.5 4.3 6.1 3.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DIE2_ALG10 PF04922.12 CDO75880.1 - 4.6e-98 329.1 19.1 1.6e-53 182.4 12.1 2.8 2 1 0 2 2 2 2 DIE2/ALG10 family TauD PF02668.16 CDO75881.1 - 6.1e-54 183.6 0.5 7.7e-54 183.3 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cu-oxidase_3 PF07732.15 CDO75881.1 - 0.094 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Multicopper oxidase OPT PF03169.15 CDO75882.1 - 1.7e-173 578.6 52.9 2e-173 578.4 52.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2418 PF10332.9 CDO75882.1 - 0.2 12.2 0.1 0.2 12.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) C2 PF00168.30 CDO75883.1 - 1.6e-82 272.5 3.7 2e-16 60.2 0.0 5.5 5 0 0 5 5 5 5 C2 domain DUF2484 PF10658.9 CDO75883.1 - 0.031 14.6 0.5 0.055 13.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) PID_2 PF14719.6 CDO75883.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) MLVIN_C PF18697.1 CDO75883.1 - 0.15 12.2 0.4 1.8 8.7 0.0 2.8 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_3 PF13358.6 CDO75884.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease GST_N_3 PF13417.6 CDO75885.1 - 9.1e-11 42.0 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO75885.1 - 4.9e-08 33.2 0.0 9.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO75885.1 - 2e-07 31.2 0.1 5.3e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO75885.1 - 0.00022 21.2 0.2 0.00045 20.2 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ATP_bind_1 PF03029.17 CDO75886.1 - 1.7e-73 247.4 0.0 2.1e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CDO75886.1 - 0.14 12.3 0.2 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NMO PF03060.15 CDO75887.1 - 2.3e-27 96.3 0.4 2.8e-24 86.2 0.2 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 CDO75887.1 - 9e-05 21.6 0.1 0.00014 21.0 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Trp_syntA PF00290.20 CDO75887.1 - 0.0054 15.6 0.0 0.0096 14.8 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain NMO PF03060.15 CDO75888.1 - 1.2e-34 120.2 0.9 4.1e-33 115.2 0.9 2.4 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 CDO75888.1 - 2.3e-07 30.2 0.4 4.9e-07 29.1 0.3 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CDO75888.1 - 9.2e-06 24.9 2.4 0.011 14.8 0.1 2.7 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 CDO75888.1 - 0.004 16.7 0.3 0.014 14.9 0.3 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein Trp_syntA PF00290.20 CDO75888.1 - 0.0086 15.0 0.0 0.021 13.7 0.0 1.6 1 0 0 1 1 1 1 Tryptophan synthase alpha chain DHO_dh PF01180.21 CDO75888.1 - 0.095 11.9 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase LSM PF01423.22 CDO75889.1 - 6.2e-16 57.8 0.0 8.7e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain RhoGEF PF00621.20 CDO75893.1 - 0.02 15.2 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 RhoGEF domain LRR_6 PF13516.6 CDO75894.1 - 3.6e-10 39.0 1.0 1.2 9.4 0.0 6.2 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 CDO75894.1 - 6.7e-06 26.4 1.4 0.88 10.1 0.0 3.9 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDO75894.1 - 0.0015 18.8 0.9 29 5.7 0.0 4.1 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_8 PF13855.6 CDO75894.1 - 0.011 15.5 0.5 14 5.6 0.1 3.5 3 0 0 3 3 3 0 Leucine rich repeat Aminotran_1_2 PF00155.21 CDO75895.1 - 1e-18 67.7 0.0 9.5e-15 54.6 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Armet PF10208.9 CDO75895.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Aminotran_MocR PF12897.7 CDO75895.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Polyketide_cyc PF03364.20 CDO75896.1 - 5.8e-11 42.7 0.0 7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Rb_C PF08934.10 CDO75897.1 - 0.035 13.9 1.6 0.1 12.4 1.6 1.8 1 0 0 1 1 1 0 Rb C-terminal domain EzrA PF06160.12 CDO75897.1 - 0.044 12.0 5.5 0.06 11.5 5.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CCDC158 PF15921.5 CDO75897.1 - 1.1 7.0 6.8 1.5 6.5 6.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 Exonuc_VII_L PF02601.15 CDO75897.1 - 2.3 7.7 10.4 3.3 7.2 10.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 CDO75897.1 - 6.1 7.4 12.5 12 6.5 12.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Integrase_H2C2 PF17921.1 CDO75899.1 - 3.4e-18 65.5 0.1 9.9e-18 64.0 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO75899.1 - 1.5e-14 54.2 0.0 2.7e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO75899.1 - 3.7e-07 29.9 0.1 7.4e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CDO75899.1 - 5.4e-07 29.7 0.1 1e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 H2C2 zinc finger RP-C_C PF11800.8 CDO75900.1 - 1.9 8.6 19.6 2.6 8.1 2.7 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Glyco_hydro_16 PF00722.21 CDO75901.1 - 2.5e-06 27.1 0.8 5.8e-06 25.9 0.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RUN PF02759.19 CDO75901.1 - 0.0053 16.7 0.2 0.04 13.9 0.0 2.0 2 0 0 2 2 2 1 RUN domain Zn_Tnp_IS1595 PF12760.7 CDO75902.1 - 0.076 13.0 3.4 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain C5HCH PF17982.1 CDO75902.1 - 2.7 8.2 8.2 7.8 6.7 8.2 1.8 1 0 0 1 1 1 0 NSD Cys-His rich domain zf-H2C2_2 PF13465.6 CDO75902.1 - 9.2 6.9 10.5 0.85 10.2 0.1 3.6 3 1 0 3 3 3 0 Zinc-finger double domain DUF601 PF04642.12 CDO75903.1 - 0.032 13.7 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Glycoamylase PF10091.9 CDO75904.1 - 0.027 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative glucoamylase Plavaka PF18759.1 CDO75908.1 - 1.4e-25 90.2 0.0 1.9e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 CDO75909.1 - 1.3e-15 57.5 2.4 2e-15 56.8 2.4 1.3 1 0 0 1 1 1 1 Plavaka transposase Myb_DNA-bind_3 PF12776.7 CDO75911.1 - 1.7e-09 38.5 0.1 2.8e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO75911.1 - 6.1e-09 36.2 0.2 1.1e-08 35.3 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO75911.1 - 0.00051 20.1 0.1 0.0017 18.4 0.1 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CDO75911.1 - 0.0025 18.0 0.3 0.0053 16.9 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myc_N PF01056.18 CDO75911.1 - 0.0028 17.6 0.7 0.005 16.8 0.7 1.4 1 0 0 1 1 1 1 Myc amino-terminal region Tub_N PF16322.5 CDO75911.1 - 0.005 17.3 1.4 0.0093 16.4 1.4 1.4 1 0 0 1 1 1 1 Tubby N-terminal LAT PF15234.6 CDO75911.1 - 0.033 13.9 2.4 0.055 13.2 2.4 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Myb_DNA-bind_6 PF13921.6 CDO75911.1 - 0.034 14.4 0.2 0.086 13.1 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain TAP42 PF04177.12 CDO75911.1 - 0.044 12.9 0.9 0.071 12.2 0.9 1.3 1 0 0 1 1 1 0 TAP42-like family TAL_effector PF03377.13 CDO75911.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 TAL effector repeat RRN3 PF05327.11 CDO75911.1 - 0.16 10.4 2.6 0.21 10.1 2.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CDO75911.1 - 0.3 9.1 3.9 0.45 8.6 3.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 CDO75911.1 - 2.5 8.5 11.8 5.2 7.5 11.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Transposase_21 PF02992.14 CDO75913.1 - 9.4e-15 54.4 0.7 3.2e-14 52.7 0.1 2.0 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 CDO75913.1 - 8.4e-05 22.2 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) APH PF01636.23 CDO75914.1 - 3.1e-15 56.8 0.2 1e-14 55.1 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO75914.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CDO75914.1 - 0.061 12.7 0.0 0.51 9.6 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mid1 PF12929.7 CDO75915.1 - 8.4e-10 38.4 0.1 1.7e-08 34.1 0.2 2.0 2 0 0 2 2 2 2 Stretch-activated Ca2+-permeable channel component APH PF01636.23 CDO75916.1 - 1.3e-14 54.8 0.1 2.1e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO75916.1 - 0.0029 17.2 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 CDO75916.1 - 0.078 12.3 0.0 0.58 9.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Proteasome PF00227.26 CDO75918.1 - 2.5e-48 164.1 0.1 3.3e-48 163.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CDO75918.1 - 1.2e-12 47.0 0.4 1.2e-12 47.0 0.4 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal BAR_2 PF10455.9 CDO75919.1 - 2.8e-48 164.5 1.8 1.2e-47 162.4 1.8 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CDO75919.1 - 2.5e-16 60.1 4.8 3e-15 56.5 4.8 2.0 1 1 0 1 1 1 1 BAR domain DUF4642 PF15484.6 CDO75919.1 - 0.046 14.0 0.4 0.077 13.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) F-box-like PF12937.7 CDO75920.1 - 0.0058 16.5 3.7 0.021 14.7 1.3 3.0 2 1 0 2 2 2 1 F-box-like adh_short PF00106.25 CDO75921.1 - 2.1e-23 82.8 0.1 3.1e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO75921.1 - 2.1e-16 60.2 0.0 3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CDO75921.1 - 7.7e-06 25.5 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CDO75921.1 - 0.00022 21.2 0.1 0.00036 20.5 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CDO75921.1 - 0.00053 19.9 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Aldedh PF00171.22 CDO75922.1 - 7.6e-123 410.4 0.0 8.5e-123 410.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 CDO75922.1 - 3.4e-07 29.6 0.0 4.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) SWIRM-assoc_3 PF16498.5 CDO75922.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal Ribosomal_S17 PF00366.20 CDO75922.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S17 ICMT PF04140.14 CDO75923.1 - 5.1e-16 58.9 1.5 6.3e-15 55.4 0.2 2.7 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO75923.1 - 1.5e-09 38.2 0.9 1.4e-08 35.0 0.2 2.5 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO75923.1 - 2.8e-08 32.9 0.2 4e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MFS_1 PF07690.16 CDO75924.1 - 4.5e-15 55.4 29.3 4.5e-15 55.4 29.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily ICMT PF04140.14 CDO75925.1 - 7.4e-14 51.9 2.5 3.1e-13 49.9 0.1 2.6 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO75925.1 - 3.8e-09 36.9 2.6 1e-08 35.5 0.6 2.4 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO75925.1 - 1.4e-07 30.7 0.2 2e-07 30.1 0.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF202 PF02656.15 CDO75925.1 - 0.36 11.3 2.8 1.4 9.4 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) ASXH PF13919.6 CDO75926.1 - 6.7e-25 87.7 0.0 1.2e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Asx homology domain Methyltransf_34 PF11312.8 CDO75929.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Cellulase PF00150.18 CDO75930.1 - 7.1e-33 114.2 1.2 1.1e-32 113.6 1.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 CDO75931.1 - 2.3e-32 112.6 2.5 3.3e-32 112.0 2.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RNase_PH PF01138.21 CDO75932.1 - 1.9e-18 67.3 0.0 3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_M24 PF00557.24 CDO75933.1 - 7.6e-57 192.4 0.0 1.1e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CDO75933.1 - 3.2e-21 75.3 0.0 5.9e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF21 PF01595.20 CDO75934.1 - 0.00015 21.5 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CDO75934.1 - 0.12 12.9 3.0 17 6.0 0.0 4.1 4 0 0 4 4 4 0 CBS domain CDC45 PF02724.14 CDO75934.1 - 3.2 6.0 6.0 4.4 5.5 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nse4_C PF08743.10 CDO75935.1 - 7.1e-31 106.3 0.0 1.4e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 CDO75935.1 - 1e-17 63.9 0.2 2.6e-17 62.7 0.2 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF948 PF06103.11 CDO75935.1 - 0.0016 18.6 0.5 0.0025 18.0 0.5 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Chloroplast_duf PF14476.6 CDO75935.1 - 0.11 11.5 0.4 0.18 10.8 0.4 1.3 1 0 0 1 1 1 0 Petal formation-expressed FlxA PF14282.6 CDO75935.1 - 0.15 12.1 0.4 0.26 11.3 0.4 1.3 1 0 0 1 1 1 0 FlxA-like protein Peptidase_C12 PF01088.21 CDO75937.1 - 2.5e-39 135.2 0.0 4.4e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CDO75937.1 - 0.002 18.0 0.3 0.0081 16.0 0.3 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Orbi_VP7 PF00897.17 CDO75937.1 - 0.2 10.6 0.1 0.9 8.5 0.0 1.9 3 0 0 3 3 3 0 Orbivirus inner capsid protein VP7 CBFD_NFYB_HMF PF00808.23 CDO75939.1 - 8.6e-17 61.2 1.1 1.4e-16 60.5 1.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDO75939.1 - 2.3e-05 24.8 0.4 2.3e-05 24.8 0.4 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF5427 PF10310.9 CDO75939.1 - 0.018 14.0 8.5 0.023 13.7 8.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) ORC6 PF05460.13 CDO75939.1 - 0.025 13.9 0.7 0.027 13.8 0.7 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TAFII28 PF04719.14 CDO75939.1 - 0.084 13.0 1.3 0.22 11.7 1.3 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region V_ATPase_I PF01496.19 CDO75939.1 - 0.59 8.0 1.5 0.59 8.0 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4746 PF15928.5 CDO75939.1 - 0.89 8.9 10.2 1.1 8.7 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 CDO75939.1 - 1.3 8.8 10.5 1.7 8.4 10.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 CDO75939.1 - 1.4 7.6 8.8 1.8 7.3 8.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLD5_C PF16922.5 CDO75940.1 - 1.9e-09 37.6 0.0 3.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CDO75940.1 - 2.5e-05 24.7 0.3 4.8e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 GINS complex protein Glyco_hydro_61 PF03443.14 CDO75941.1 - 1.9e-52 178.2 0.0 3.9e-52 177.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.19 CDO75942.1 - 5.1e-19 68.7 5.3 2.7e-17 63.0 5.3 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 CDO75942.1 - 4.6e-06 26.5 0.6 7.6e-06 25.7 0.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDO75942.1 - 0.00055 20.1 0.1 0.0013 18.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDO75942.1 - 0.0076 15.4 0.0 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CDO75942.1 - 0.0083 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 CDO75942.1 - 0.035 13.1 0.1 0.35 9.9 0.0 2.1 1 1 0 2 2 2 0 Squalene epoxidase Glyco_hydro_61 PF03443.14 CDO75943.1 - 4e-58 196.7 0.1 4e-58 196.7 0.1 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 SOG2 PF10428.9 CDO75943.1 - 0.48 9.6 27.4 0.71 9.0 27.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Utp14 PF04615.13 CDO75943.1 - 6.3 5.2 26.1 8.2 4.9 26.1 1.0 1 0 0 1 1 1 0 Utp14 protein HMG_box_2 PF09011.10 CDO75944.1 - 0.062 13.9 0.1 0.062 13.9 0.1 2.3 2 0 0 2 2 2 0 HMG-box domain V_ATPase_I PF01496.19 CDO75944.1 - 0.34 8.8 1.6 0.47 8.3 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HMG_box PF00505.19 CDO75944.1 - 1.9 8.9 4.8 0.5 10.8 0.2 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box KDZ PF18758.1 CDO75946.1 - 9e-42 143.2 0.0 6.2e-39 133.9 0.0 2.5 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CDPS PF16715.5 CDO75946.1 - 0.7 9.5 5.5 0.97 9.0 1.5 2.9 1 1 1 2 2 2 0 Cyclodipeptide synthase GramPos_pilinD1 PF16555.5 CDO75947.1 - 0.018 15.2 1.2 0.019 15.1 1.2 1.2 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain DUF3446 PF11928.8 CDO75947.1 - 9.2 6.7 11.5 6.1 7.2 8.3 2.2 2 1 1 3 3 3 0 Early growth response N-terminal domain Pkinase_fungal PF17667.1 CDO75948.1 - 3.3e-38 131.6 0.0 5.4e-26 91.3 0.0 3.5 2 2 0 2 2 2 2 Fungal protein kinase APH PF01636.23 CDO75948.1 - 0.0097 15.8 0.1 0.81 9.6 0.0 2.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3306 PF11748.8 CDO75948.1 - 2.6 8.9 8.2 17 6.3 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) RVT_1 PF00078.27 CDO75949.1 - 3.2e-29 102.1 0.0 3.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO75950.1 - 1.4e-09 38.2 0.0 5e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 CDO75950.1 - 0.0024 18.5 0.0 0.0064 17.2 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FKBP_C PF00254.28 CDO75951.1 - 2.3e-35 120.8 0.0 3e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Anophelin PF10731.9 CDO75951.1 - 0.078 12.8 0.2 0.15 11.9 0.2 1.4 1 1 0 1 1 1 0 Thrombin inhibitor from mosquito Imm49 PF15575.6 CDO75951.1 - 0.081 12.7 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 49 FCH PF00611.23 CDO75954.1 - 5.2e-16 58.7 0.3 1.6e-15 57.1 0.3 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1690 PF07956.11 CDO75954.1 - 5.7 7.4 8.9 2 8.9 5.2 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Asp_Glu_race PF01177.22 CDO75955.1 - 3e-07 30.5 0.1 1.5e-06 28.2 0.1 1.9 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Abhydrolase_4 PF08386.10 CDO75956.1 - 0.00055 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_4 PF08386.10 CDO75957.1 - 8e-08 32.3 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 CDO75957.1 - 0.0023 17.6 0.0 0.0079 15.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.11 CDO75958.1 - 5.7e-14 52.7 7.4 4e-12 46.7 1.3 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PseudoU_synth_2 PF00849.22 CDO75959.1 - 5.4e-15 55.8 0.0 7.5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase MFS_1 PF07690.16 CDO75960.1 - 2e-30 106.0 20.6 3.8e-30 105.0 20.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO75960.1 - 6.5e-06 25.3 4.3 6.5e-06 25.3 4.3 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CDO75960.1 - 6.3e-05 21.6 0.3 6.3e-05 21.6 0.3 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Beta-lactamase PF00144.24 CDO75962.1 - 7.8e-30 104.2 0.9 3.3e-29 102.2 0.9 1.9 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 CDO75962.1 - 0.027 14.9 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Ank_2 PF12796.7 CDO75964.1 - 1.3e-06 28.9 0.0 0.00065 20.2 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CDO75964.1 - 1.9e-06 27.7 0.0 0.035 14.7 0.0 4.0 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 CDO75964.1 - 7.2e-06 26.2 0.1 0.0026 18.0 0.0 3.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CDO75964.1 - 0.00023 21.5 0.1 0.072 13.6 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CDO75964.1 - 0.00077 20.0 0.3 0.24 12.1 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) FlgD_ig PF13860.6 CDO75964.1 - 0.0076 16.1 0.5 0.029 14.2 0.1 2.2 2 0 0 2 2 2 1 FlgD Ig-like domain GATase_7 PF13537.6 CDO75964.1 - 0.13 12.2 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase domain Uso1_p115_head PF04869.14 CDO75965.1 - 1.2e-40 139.6 0.0 3.5e-30 105.2 0.0 4.1 3 1 0 3 3 3 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 CDO75965.1 - 2.3e-15 57.1 21.2 3.8e-15 56.4 21.2 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Seryl_tRNA_N PF02403.22 CDO75965.1 - 0.0026 18.0 4.6 0.0085 16.3 4.6 1.9 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain HEAT_2 PF13646.6 CDO75965.1 - 0.0034 17.7 0.0 0.0034 17.7 0.0 3.7 3 1 1 4 4 2 1 HEAT repeats Atx10homo_assoc PF09759.9 CDO75965.1 - 0.0045 17.0 0.3 11 6.1 0.0 4.0 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Laminin_II PF06009.12 CDO75965.1 - 0.054 13.5 5.9 0.11 12.5 5.9 1.4 1 0 0 1 1 1 0 Laminin Domain II SlyX PF04102.12 CDO75965.1 - 0.079 13.6 11.1 0.19 12.4 0.7 3.0 1 1 1 2 2 2 0 SlyX Cnd1 PF12717.7 CDO75965.1 - 0.21 11.6 1.4 1.3 9.1 0.0 2.6 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 MIF4G_like_2 PF09090.11 CDO75965.1 - 0.27 10.7 4.7 0.46 9.9 4.7 1.3 1 0 0 1 1 1 0 MIF4G like Adaptin_N PF01602.20 CDO75965.1 - 0.3 9.6 4.0 5.6 5.4 0.0 2.7 2 1 1 3 3 3 0 Adaptin N terminal region APG6_N PF17675.1 CDO75965.1 - 0.6 10.6 17.2 1.4 9.4 17.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region NPV_P10 PF05531.12 CDO75965.1 - 0.68 10.4 4.2 1.9 9.0 4.2 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 CDO75965.1 - 0.77 9.2 11.0 1.3 8.5 11.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_GPO PF05929.11 CDO75965.1 - 0.88 9.1 4.9 1.5 8.4 4.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3818 PF12825.7 CDO75965.1 - 1.2 8.1 6.9 1.9 7.4 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Mo25 PF08569.11 CDO75965.1 - 1.2 8.4 4.8 0.23 10.8 0.1 2.0 2 0 0 2 2 2 0 Mo25-like Ead_Ea22 PF13935.6 CDO75965.1 - 2 9.1 10.1 2.3 8.9 2.6 2.4 1 1 1 2 2 2 0 Ead/Ea22-like protein CENP-H PF05837.12 CDO75965.1 - 2.2 8.7 10.2 3.4 8.1 9.2 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 CDO75965.1 - 2.6 7.9 13.2 6.2 6.7 1.1 3.1 3 1 1 4 4 2 0 Septum formation initiator FlxA PF14282.6 CDO75965.1 - 3.6 7.6 10.1 2.3e+02 1.8 10.1 2.6 2 1 0 2 2 1 0 FlxA-like protein Atg14 PF10186.9 CDO75965.1 - 4 6.4 5.4 6.5 5.7 5.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 CDO75965.1 - 4.2 7.9 6.7 16 6.0 6.7 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HEAT PF02985.22 CDO75965.1 - 5.3 7.6 6.2 1.4e+02 3.2 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat YabA PF06156.13 CDO75965.1 - 5.8 7.6 6.9 5.9 7.6 5.1 1.7 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 CDO75965.1 - 5.9 6.2 7.1 9.7 5.4 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Aminotran_5 PF00266.19 CDO75966.1 - 7.4e-29 100.8 0.0 6.4e-28 97.8 0.0 1.9 2 0 0 2 2 2 2 Aminotransferase class-V Cwf_Cwc_15 PF04889.12 CDO75967.1 - 9.2e-88 294.1 28.6 1e-87 294.0 28.6 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 CDO75967.1 - 0.037 12.3 25.1 0.044 12.0 25.1 1.1 1 0 0 1 1 1 0 Nop14-like family CNDH2_C PF16858.5 CDO75967.1 - 0.054 13.4 14.5 0.065 13.1 14.5 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term MFAP1 PF06991.11 CDO75967.1 - 1.3 8.8 35.8 3.5 7.4 35.9 1.6 1 1 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing ALMT PF11744.8 CDO75967.1 - 1.9 7.3 4.9 2.2 7.0 4.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter K_channel_TID PF07941.11 CDO75967.1 - 2.1 8.9 8.6 2.8 8.5 1.1 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF2151 PF10221.9 CDO75967.1 - 2.8 6.4 6.9 3.7 6.0 6.9 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator TFIIF_alpha PF05793.12 CDO75967.1 - 3.3 6.2 28.4 4.4 5.8 28.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.15 CDO75967.1 - 4 6.1 11.5 4.4 6.0 11.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sacchrp_dh_NADP PF03435.18 CDO75968.1 - 2.1e-14 53.9 0.0 3.6e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CDO75968.1 - 3.1e-09 37.0 0.0 4.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CDO75968.1 - 0.00033 20.2 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CDO75968.1 - 0.00046 20.6 0.0 0.00085 19.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CDO75968.1 - 0.0034 16.4 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 CDO75968.1 - 0.0049 16.8 0.1 0.0097 15.8 0.1 1.4 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 CDO75968.1 - 0.02 15.0 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 CDO75968.1 - 0.024 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 CDO75969.1 - 1.1e-14 54.8 0.1 1.5e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CDO75969.1 - 9.3e-09 35.4 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CDO75969.1 - 1.7e-06 27.7 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CDO75969.1 - 7.8e-06 26.3 0.0 1.2e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 CDO75969.1 - 0.00039 20.0 0.0 0.00053 19.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 CDO75969.1 - 0.0017 18.3 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 CDO75969.1 - 0.0074 15.3 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CDO75969.1 - 0.05 12.8 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.20 CDO75969.1 - 0.055 13.6 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF1479 PF07350.12 CDO75970.1 - 3.6e-133 444.4 0.0 5.5e-121 404.2 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) IKI3 PF04762.12 CDO75971.1 - 3e-239 796.7 0.0 2.7e-182 608.2 0.0 2.4 1 1 1 2 2 2 2 IKI3 family Clathrin PF00637.20 CDO75971.1 - 0.044 13.7 2.9 2.7 7.9 0.0 3.8 2 1 2 4 4 4 0 Region in Clathrin and VPS TPR_12 PF13424.6 CDO75971.1 - 0.053 13.8 2.2 0.39 11.0 0.3 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TMF_TATA_bd PF12325.8 CDO75971.1 - 0.33 11.2 3.3 1.6 9.0 0.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FliJ PF02050.16 CDO75971.1 - 2.2 8.5 7.4 0.33 11.2 2.6 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein Apolipoprotein PF01442.18 CDO75971.1 - 9.3 6.1 11.1 9.1 6.1 1.7 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DDE_1 PF03184.19 CDO75972.1 - 2.2e-22 79.5 0.0 4e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CDO75972.1 - 4.3e-07 29.9 0.3 1.2e-06 28.4 0.3 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 CDO75972.1 - 0.0029 17.3 0.1 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Secretin_N_2 PF07655.13 CDO75972.1 - 0.19 12.3 8.0 0.29 11.7 6.8 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain Peptidase_S64 PF08192.11 CDO75972.1 - 1.9 6.9 5.2 2.8 6.3 5.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 YLP PF02757.17 CDO75973.1 - 0.083 12.9 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 YLP motif Transposase_21 PF02992.14 CDO75975.1 - 1.6e-09 37.4 0.9 3.1e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Transposase family tnp2 TOBE_2 PF08402.10 CDO75975.1 - 0.04 14.1 1.0 0.26 11.5 0.0 2.7 3 0 0 3 3 3 0 TOBE domain WD40 PF00400.32 CDO75976.1 - 2.2e-14 53.6 6.5 0.00047 20.9 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO75976.1 - 3.1e-06 27.4 1.0 0.0093 16.3 0.1 2.8 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO75976.1 - 1.7e-05 24.0 0.3 0.026 13.5 0.1 3.0 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Ras PF00071.22 CDO75977.1 - 2.6e-55 186.4 0.0 3.1e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO75977.1 - 8.7e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO75977.1 - 8.9e-07 28.5 0.0 1.4e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CDO75977.1 - 0.003 17.0 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CDO75977.1 - 0.22 10.9 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AKAP7_NLS PF10469.9 CDO75978.1 - 1.8e-20 73.7 0.0 3.6e-20 72.8 0.0 1.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain FoP_duplication PF13865.6 CDO75978.1 - 1.6 9.4 7.2 3 8.5 7.2 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Asp PF00026.23 CDO75979.1 - 4.8e-17 62.3 0.0 8.3e-15 55.0 0.1 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Integrase_H2C2 PF17921.1 CDO75981.1 - 6.1e-16 58.3 0.5 1.2e-15 57.3 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO75981.1 - 2.5e-11 43.8 0.0 4.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDO75981.1 - 1.4e-06 28.4 0.2 2.4e-06 27.7 0.2 1.4 1 0 0 1 1 1 1 H2C2 zinc finger NolX PF05819.11 CDO75981.1 - 0.14 11.5 0.2 0.18 11.1 0.2 1.1 1 0 0 1 1 1 0 NolX protein RT_RNaseH PF17917.1 CDO75982.1 - 2.6e-37 127.3 0.0 4.7e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO75982.1 - 1.1e-31 108.8 0.0 2.1e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO75982.1 - 2.2e-31 109.1 0.0 3.4e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FOXP-CC PF16159.5 CDO75983.1 - 0.093 13.4 0.7 0.34 11.6 0.0 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain TFIIS_M PF07500.14 CDO75985.1 - 4.6e-19 69.0 1.2 1e-18 67.8 1.2 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 CDO75985.1 - 1.8e-10 40.9 0.0 3.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 CDO75985.1 - 5e-08 32.7 4.2 9.5e-08 31.8 4.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CDO75985.1 - 0.019 15.2 0.7 0.042 14.1 0.7 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CDO75985.1 - 0.15 12.2 0.6 0.28 11.4 0.6 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain Abhydrolase_3 PF07859.13 CDO75986.1 - 1.1e-23 84.2 0.0 1.8e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDO75986.1 - 1.3e-09 37.4 0.0 1.7e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 CDO75986.1 - 0.00022 21.9 2.0 0.00036 21.2 2.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.22 CDO75988.1 - 1.9e-63 214.8 0.0 1.1e-62 212.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 p450 PF00067.22 CDO75989.1 - 5.7e-66 223.2 0.0 1.1e-65 222.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.23 CDO75991.1 - 2.3e-22 79.8 0.1 3.6e-20 72.6 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CDO75991.1 - 5e-06 27.1 1.0 4.1e-05 24.1 0.2 2.6 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDO75991.1 - 0.00086 19.8 0.1 0.067 13.7 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 CDO75991.1 - 0.025 14.8 0.1 0.25 11.5 0.1 2.3 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal Herpes_capsid PF06112.11 CDO75991.1 - 2.2 8.3 8.4 3.9 7.5 8.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Period_C PF12114.8 CDO75991.1 - 8.1 6.0 7.0 13 5.3 7.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Ferritin_2 PF13668.6 CDO75992.1 - 4.2e-22 78.8 1.8 4.3e-22 78.8 0.5 1.7 2 0 0 2 2 2 1 Ferritin-like domain DUF4449 PF14613.6 CDO75993.1 - 1.5e-32 113.0 0.1 1.5e-32 113.0 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) DUF1687 PF07955.11 CDO75993.1 - 0.053 14.0 2.5 0.054 14.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) TetR_C_11 PF16859.5 CDO75993.1 - 0.49 10.7 8.4 0.15 12.4 0.4 3.3 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain RVT_1 PF00078.27 CDO75994.1 - 8.7e-24 84.3 0.0 1.4e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO75994.1 - 6.2e-09 36.2 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.6 CDO75994.1 - 1.2e-05 25.1 0.1 2.7e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 CDO75994.1 - 0.0012 19.5 0.0 0.0033 18.1 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase UBN_AB PF14075.6 CDO75995.1 - 6.9e-20 71.7 0.5 2.4e-09 37.3 0.0 3.0 2 1 1 3 3 3 2 Ubinuclein conserved middle domain HUN PF08729.10 CDO75995.1 - 2.4e-13 49.8 0.1 2.4e-13 49.8 0.1 2.2 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Lipase_GDSL_2 PF13472.6 CDO75996.1 - 2.4e-10 41.1 0.4 3.3e-10 40.7 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CDO75996.1 - 7.2e-06 26.1 0.0 4e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase La PF05383.17 CDO75997.1 - 3.3e-22 78.3 0.0 6.6e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CDO75997.1 - 2e-07 30.7 0.1 4.9e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1330 PF07045.11 CDO75997.1 - 0.024 15.0 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) Inhibitor_I34 PF10466.9 CDO75997.1 - 0.54 10.9 5.1 0.23 12.1 0.4 2.6 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 Fungal_trans PF04082.18 CDO75998.1 - 7.6e-10 38.3 0.1 2.3e-09 36.7 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CDO75998.1 - 2.9e-07 30.5 7.6 7e-07 29.3 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 CDO75999.1 - 2.7e-12 45.9 0.1 2.7e-12 45.9 0.1 2.7 3 0 0 3 3 3 1 Histone chaperone domain CHZ MRC1 PF09444.10 CDO75999.1 - 0.015 15.8 9.2 0.015 15.8 9.2 2.2 2 0 0 2 2 2 0 MRC1-like domain PBP1_TM PF14812.6 CDO75999.1 - 0.17 12.3 37.7 0.69 10.3 4.2 3.1 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_fiss_reg PF05308.11 CDO75999.1 - 0.41 10.7 8.7 0.63 10.1 8.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4551 PF15087.6 CDO75999.1 - 1.1 8.0 9.1 1 8.1 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RAP1 PF07218.11 CDO75999.1 - 1.5 7.0 12.1 1.8 6.8 12.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF908 PF06012.12 CDO75999.1 - 3.9 6.8 6.5 4.1 6.7 6.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TMEM214 PF10151.9 CDO75999.1 - 8.2 4.8 6.7 8.7 4.7 6.7 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator ACOX PF01756.19 CDO76000.1 - 4.4e-29 101.3 0.0 8.9e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 CDO76000.1 - 3.2e-20 72.9 0.0 5.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 CDO76000.1 - 5e-08 33.0 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CDO76000.1 - 0.00056 20.1 0.9 0.0022 18.2 0.3 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DHHC PF01529.20 CDO76001.1 - 1.5e-33 115.7 9.1 1.5e-33 115.7 9.1 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CDO76001.1 - 2.1e-31 108.4 0.1 3.6e-15 56.3 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDO76001.1 - 6.8e-27 93.5 1.3 9.6e-07 29.2 0.0 5.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CDO76001.1 - 8e-27 93.0 4.3 2.5e-11 43.6 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CDO76001.1 - 9.7e-24 82.7 6.7 2.4e-05 24.5 0.1 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 CDO76001.1 - 7.5e-22 75.1 1.3 0.00068 19.9 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Cupin_1 PF00190.22 CDO76001.1 - 1e-10 41.4 0.0 1.9e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 CDO76001.1 - 0.00022 20.9 0.0 0.00022 20.9 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 CDO76001.1 - 0.08 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PocR PF10114.9 CDO76001.1 - 1.3 8.8 2.8 2.9 7.6 2.8 1.5 1 0 0 1 1 1 0 Sensory domain found in PocR Cupin_1 PF00190.22 CDO76002.1 - 9.2e-30 103.2 0.0 6.2e-14 51.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CDO76002.1 - 4.1e-18 64.8 0.1 7e-08 32.1 0.0 3.0 2 1 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 CDO76002.1 - 4.6e-05 23.3 0.4 0.0019 18.1 0.1 2.7 2 1 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 CDO76002.1 - 0.00083 19.0 0.0 0.0089 15.7 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF861) 3-HAO PF06052.12 CDO76002.1 - 0.16 11.6 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase EF1G PF00647.19 CDO76003.1 - 2.2e-45 153.1 0.0 3.7e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 CDO76003.1 - 7.9e-15 55.0 0.0 2e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CDO76003.1 - 4.2e-11 42.9 0.0 1.4e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO76003.1 - 3.4e-08 33.4 0.0 1e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDO76003.1 - 4.6e-08 33.3 0.0 9.7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDO76003.1 - 1.7e-07 31.3 0.0 5.1e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CDO76003.1 - 0.0079 16.5 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.19 CDO76003.1 - 0.07 13.7 7.1 0.16 12.6 7.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein UPF0524 PF15823.5 CDO76003.1 - 0.08 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 GST_C_6 PF17171.4 CDO76003.1 - 0.097 12.5 0.1 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PhoLip_ATPase_C PF16212.5 CDO76004.1 - 7.6e-51 173.3 23.9 7.6e-51 173.3 23.9 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDO76004.1 - 9.1e-17 60.5 5.6 2.1e-16 59.3 5.6 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CDO76004.1 - 4.2e-15 56.6 0.6 5.5e-12 46.4 0.6 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CDO76004.1 - 1.2e-13 50.9 0.0 1.2e-13 50.9 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CDO76004.1 - 1.3e-09 38.0 0.0 4.1e-08 33.2 0.0 2.8 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDO76004.1 - 0.00019 21.2 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Prot_ATP_ID_OB PF16450.5 CDO76004.1 - 0.17 11.9 0.1 0.58 10.2 0.1 1.9 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain NST1 PF13945.6 CDO76005.1 - 2.6e-57 194.1 0.0 2.6e-57 194.1 0.0 4.1 4 1 1 5 5 5 1 Salt tolerance down-regulator Pox_Ag35 PF03286.14 CDO76006.1 - 0.15 11.8 1.1 0.24 11.2 1.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3246 PF11596.8 CDO76006.1 - 0.26 10.7 2.1 0.44 9.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Glyco_hydro_79C PF16862.5 CDO76007.1 - 4.5e-20 72.4 1.2 1.1e-19 71.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79C PF16862.5 CDO76008.1 - 5.6e-14 52.9 0.7 1.3e-13 51.7 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain SSURE PF11966.8 CDO76008.1 - 0.039 13.7 0.4 2.8 7.8 0.0 2.5 1 1 1 2 2 2 0 Fibronectin-binding repeat Hist_deacetyl PF00850.19 CDO76009.1 - 3.5e-88 296.0 0.0 5.8e-88 295.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 CDO76009.1 - 3.6e-41 141.0 0.0 4.6e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain OSCP PF00213.18 CDO76010.1 - 3.1e-38 131.6 0.9 3.6e-38 131.4 0.9 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Glutaredoxin2_C PF04399.13 CDO76010.1 - 0.12 12.2 0.2 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain TRP PF06011.12 CDO76011.1 - 5.3e-68 229.7 26.3 1.3e-67 228.4 26.3 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CDO76011.1 - 9.3e-29 100.6 0.6 1.6e-28 99.8 0.6 1.4 1 0 0 1 1 1 1 ML-like domain DUF3671 PF12420.8 CDO76011.1 - 3.2 7.9 4.0 2 8.5 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function UDPGP PF01704.18 CDO76013.1 - 2.8e-200 665.3 1.3 3.2e-200 665.1 1.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ribosomal_S8e PF01201.22 CDO76014.1 - 1.6e-50 170.8 0.4 2.4e-50 170.3 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Cylicin_N PF15241.6 CDO76014.1 - 0.055 13.6 0.2 0.1 12.7 0.2 1.5 1 0 0 1 1 1 0 Cylicin N-terminus SET PF00856.28 CDO76015.1 - 1.9e-08 34.9 0.1 4e-07 30.6 0.1 3.0 1 1 0 1 1 1 1 SET domain AT_hook PF02178.19 CDO76015.1 - 0.00036 20.1 15.3 0.052 13.4 1.3 3.6 2 0 0 2 2 2 2 AT hook motif Cpn60_TCP1 PF00118.24 CDO76016.1 - 4.9e-157 523.5 0.0 9.7e-156 519.2 0.0 2.1 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family EthD PF07110.11 CDO76017.1 - 2.1e-12 48.0 0.1 2.8e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 CDO76017.1 - 3.2e-09 37.2 0.1 4e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase EthD PF07110.11 CDO76018.1 - 7e-14 52.8 0.1 8.5e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 CDO76018.1 - 0.0047 17.4 0.0 0.0082 16.6 0.0 1.5 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase APC1_C PF18122.1 CDO76019.1 - 7.3e-35 120.4 0.2 1.3e-34 119.6 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 CDO76019.1 - 6.2e-06 26.4 13.0 0.22 12.0 0.0 5.8 6 0 0 6 6 6 4 Proteasome/cyclosome repeat ANAPC1 PF12859.7 CDO76020.1 - 7.2e-09 36.3 1.6 7.2e-09 36.3 1.6 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 adh_short_C2 PF13561.6 CDO76021.1 - 3.5e-44 151.1 0.2 3.8e-26 92.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO76021.1 - 1.4e-29 103.0 0.3 2.4e-19 69.6 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 CDO76021.1 - 7.7e-10 39.0 0.1 1.1e-09 38.5 0.1 1.3 1 0 0 1 1 1 1 KR domain SbcD_C PF12320.8 CDO76021.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain ThiF PF00899.21 CDO76021.1 - 0.17 11.2 0.6 5.1 6.4 0.0 2.3 1 1 1 2 2 2 0 ThiF family NAD_binding_8 PF13450.6 CDO76022.1 - 3.3e-14 52.9 0.8 8.2e-14 51.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CDO76022.1 - 4.1e-08 33.2 0.2 1.7e-07 31.2 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDO76022.1 - 2.3e-05 23.7 0.0 4.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 CDO76022.1 - 3.4e-05 23.2 0.4 6.3e-05 22.4 0.2 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO76022.1 - 4.1e-05 23.6 1.2 0.00046 20.2 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CDO76022.1 - 7.4e-05 22.0 0.2 0.00011 21.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CDO76022.1 - 0.00054 18.8 0.2 0.0034 16.1 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 CDO76022.1 - 0.00074 18.9 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 CDO76022.1 - 0.0065 15.9 0.4 0.0065 15.9 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDO76022.1 - 0.024 13.9 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 CDO76022.1 - 0.031 14.8 0.1 0.35 11.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 CDO76022.1 - 0.043 12.6 0.0 0.084 11.7 0.0 1.4 1 0 0 1 1 1 0 MCRA family GIDA PF01134.22 CDO76022.1 - 0.094 11.8 0.3 0.15 11.1 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CDO76022.1 - 0.15 11.4 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 CDO76023.1 - 9.1e-26 90.5 0.0 1.3e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO76023.1 - 3e-16 59.7 0.0 4.5e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO76023.1 - 2.7e-10 40.4 0.1 4.2e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO76023.1 - 0.00011 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CDO76023.1 - 0.00082 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CDO76023.1 - 0.0048 16.3 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ADSL_C PF10397.9 CDO76023.1 - 0.06 13.9 0.1 0.15 12.7 0.1 1.6 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminus FKBP_C PF00254.28 CDO76024.1 - 1.1e-31 109.0 0.0 3.3e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CDO76024.1 - 1.5e-21 76.9 0.0 1.5e-21 76.9 0.0 2.5 2 1 0 2 2 2 1 Nucleoplasmin-like domain DUF4604 PF15377.6 CDO76024.1 - 1.8 9.0 30.9 1 9.8 24.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) ARPC4 PF05856.12 CDO76025.1 - 2.1e-79 265.0 5.7 2.3e-79 264.8 5.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) COesterase PF00135.28 CDO76026.1 - 5.2e-72 243.4 0.0 7.7e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CDO76026.1 - 1.1e-07 32.0 0.1 4.4e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Scs3p PF10261.9 CDO76027.1 - 2.5e-40 138.5 2.6 2.6e-33 115.6 0.0 2.1 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM Ribosomal_L14e PF01929.17 CDO76028.1 - 3e-21 75.7 0.6 5.1e-21 74.9 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 DRY_EERY PF09750.9 CDO76028.1 - 0.069 13.4 0.8 0.12 12.6 0.8 1.4 1 0 0 1 1 1 0 Alternative splicing regulator Fungal_trans PF04082.18 CDO76030.1 - 1.6e-11 43.7 0.0 3.4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CDO76030.1 - 4.5e-07 29.9 12.6 8.4e-07 29.0 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.28 CDO76031.1 - 2.4e-62 211.5 3.7 2.8e-62 211.3 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL10 PF02638.15 CDO76031.1 - 0.0004 19.6 0.0 0.00065 18.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 TetR_C_28 PF17937.1 CDO76033.1 - 0.051 14.0 0.1 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RVT_3 PF13456.6 CDO76033.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 Reverse transcriptase-like RVT_2 PF07727.14 CDO76034.1 - 7.8e-65 218.9 0.0 1.2e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CDO76034.1 - 1.8e-28 98.9 0.6 3.1e-28 98.2 0.6 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO76034.1 - 1.3e-12 47.3 0.1 9.3e-12 44.6 0.0 2.4 2 0 0 2 2 2 1 GAG-pre-integrase domain DUF4219 PF13961.6 CDO76034.1 - 3.3e-06 26.6 0.0 8.4e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 CDO76034.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type rve PF00665.26 CDO76034.1 - 0.075 13.2 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain zf-CCHC PF00098.23 CDO76034.1 - 4 7.7 4.8 4.1 7.6 3.0 1.9 2 0 0 2 2 2 0 Zinc knuckle rve PF00665.26 CDO76035.1 - 2.8e-21 75.9 0.0 5.6e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO76035.1 - 1.1e-10 41.3 0.0 6.3e-10 38.9 0.0 2.0 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO76035.1 - 4.7e-09 36.0 0.1 1.1e-08 34.8 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO76035.1 - 0.00026 20.7 0.1 0.00054 19.7 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain DEAD PF00270.29 CDO76036.1 - 1.4e-13 51.0 0.0 2.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO76036.1 - 5.7e-13 49.2 0.0 6.6e-12 45.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4638 PF15472.6 CDO76036.1 - 1.4 8.5 17.5 1.7 8.3 12.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4638) DUF2052 PF09747.9 CDO76036.1 - 2.2 8.4 17.0 4.2 7.4 17.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CDO76036.1 - 2.9 7.6 11.8 5.7 6.7 11.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3987 PF13148.6 CDO76036.1 - 4.2 6.3 16.3 1.5 7.7 13.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) CDC45 PF02724.14 CDO76036.1 - 9.6 4.4 11.7 14 3.8 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein rve PF00665.26 CDO76039.1 - 6e-11 42.6 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO76039.1 - 5.7e-08 32.5 0.3 1.1e-07 31.6 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH_2 PF17919.1 CDO76040.1 - 1.4e-36 124.5 0.0 2.8e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO76040.1 - 8.9e-32 109.5 0.0 1.7e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO76040.1 - 2.3e-24 86.2 0.1 4.3e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 CDO76041.1 - 3.6e-73 246.2 0.0 4.8e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDO76041.1 - 0.021 14.3 0.1 0.064 12.8 0.1 1.9 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 CDO76042.1 - 1.3e-73 247.6 0.0 1.7e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3275 PF11679.8 CDO76042.1 - 2.1 8.3 4.9 4.2 7.3 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DSPc PF00782.20 CDO76043.1 - 2.5e-06 27.4 0.0 3.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDO76043.1 - 7.5e-06 26.1 0.0 1.7e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 CDO76043.1 - 3.9e-05 23.4 0.0 5.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 CDO76043.1 - 0.001 18.7 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CDO76043.1 - 0.0041 17.3 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Amidohydro_3 PF07969.11 CDO76044.1 - 2e-14 53.9 8.1 2e-08 34.1 0.0 4.3 5 0 0 5 5 5 3 Amidohydrolase family Amidohydro_1 PF01979.20 CDO76044.1 - 2.1e-11 43.7 0.0 1.3e-08 34.6 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Pkinase PF00069.25 CDO76045.1 - 2e-59 201.1 0.0 4.2e-29 101.7 0.0 4.7 4 0 0 4 4 4 4 Protein kinase domain HGTP_anticodon2 PF12745.7 CDO76045.1 - 5.3e-43 147.4 2.6 9.8e-42 143.3 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 CDO76045.1 - 2e-27 96.1 0.0 7e-12 45.2 0.0 4.3 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 CDO76045.1 - 1.1e-13 51.5 0.7 2.8e-12 47.0 0.0 2.7 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 CDO76045.1 - 1.9e-13 50.3 1.5 7.2e-13 48.5 0.0 2.3 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 CDO76045.1 - 0.00016 21.7 0.0 0.00016 21.7 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 CDO76045.1 - 0.0015 18.2 0.0 6.9 6.2 0.0 3.4 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Gcn1_N PF12074.8 CDO76045.1 - 0.03 13.6 0.1 0.67 9.2 0.0 2.4 2 0 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Exonuc_VII_L PF02601.15 CDO76045.1 - 0.052 13.1 5.1 4.8 6.7 5.3 2.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit RlaP PF10127.9 CDO76045.1 - 0.21 11.1 4.3 0.47 10.0 4.3 1.5 1 0 0 1 1 1 0 RNA repair pathway DNA polymerase beta family Haspin_kinase PF12330.8 CDO76045.1 - 1.8 7.4 3.8 0.62 8.9 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain LysM PF01476.20 CDO76046.1 - 8.4e-08 32.2 0.0 5.2e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 LysM domain Pkinase_fungal PF17667.1 CDO76047.1 - 1.7e-24 86.3 0.0 2.2e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO76048.1 - 5.2e-21 74.9 0.1 7.8e-21 74.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CDO76048.1 - 6.5e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76048.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 CDO76048.1 - 0.014 14.8 0.2 0.025 13.9 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.14 CDO76048.1 - 0.022 13.1 25.0 0.034 12.4 25.0 1.3 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 CDO76048.1 - 0.26 10.0 6.0 0.31 9.8 6.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_Rpc4 PF05132.14 CDO76048.1 - 3 8.3 4.8 5.9 7.3 4.8 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Afi1 PF07792.12 CDO76048.1 - 3.4 8.2 16.2 6.9 7.2 16.2 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Zip PF02535.22 CDO76048.1 - 7.3 5.7 10.7 10 5.2 10.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MMtag PF10159.9 CDO76050.1 - 6.7e-31 106.4 2.4 6.7e-31 106.4 2.4 3.0 2 1 1 3 3 3 1 Multiple myeloma tumor-associated Rtf2 PF04641.12 CDO76050.1 - 2 7.7 11.1 0.23 10.8 6.9 1.5 2 0 0 2 2 2 0 Rtf2 RING-finger R3H PF01424.22 CDO76051.1 - 7.7e-13 48.2 0.3 2.9e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 R3H domain Use1 PF09753.9 CDO76052.1 - 3e-15 56.6 0.1 3.6e-15 56.4 0.1 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 LAP1C PF05609.12 CDO76052.1 - 0.0044 16.2 0.0 0.0051 16.0 0.0 1.0 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Tektin PF03148.14 CDO76052.1 - 0.026 13.3 3.3 0.032 13.0 3.3 1.0 1 0 0 1 1 1 0 Tektin family Pox_EPC_I2-L1 PF12575.8 CDO76052.1 - 0.066 13.4 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 KELK PF15796.5 CDO76052.1 - 0.1 13.1 5.6 0.15 12.6 5.6 1.1 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Orf78 PF06024.12 CDO76052.1 - 0.13 12.6 0.1 0.23 11.8 0.0 1.4 1 1 0 1 1 1 0 Orf78 (ac78) Mannosidase_ig PF17786.1 CDO76054.1 - 3.5e-16 59.6 0.6 1.2e-15 57.9 0.6 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 CDO76054.1 - 7.9e-16 57.6 0.0 4.1e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2 PF00703.21 CDO76054.1 - 1e-06 29.4 0.0 0.00012 22.7 0.0 3.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 CDO76054.1 - 0.0079 16.1 0.1 0.38 10.7 0.1 3.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain AA_permease PF00324.21 CDO76055.1 - 8.6e-107 357.7 37.0 1.5e-94 317.3 20.1 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 CDO76055.1 - 4.7e-25 88.3 34.7 8e-24 84.2 20.7 2.1 1 1 1 2 2 2 2 Amino acid permease DUF5056 PF16479.5 CDO76055.1 - 0.13 12.5 1.2 0.62 10.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) DUF2759 PF10958.8 CDO76055.1 - 0.37 10.6 5.8 1.8 8.4 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) DUF4231 PF14015.6 CDO76055.1 - 1 9.9 9.2 1.4e+02 3.0 0.0 4.8 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) S-methyl_trans PF02574.16 CDO76056.1 - 1.3e-49 169.5 0.0 1.6e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase BILBO1_N PF18281.1 CDO76056.1 - 0.11 12.9 0.1 0.6 10.6 0.0 2.0 2 0 0 2 2 2 0 BILBO1 N-terminal domain Kelch_1 PF01344.25 CDO76056.1 - 0.14 11.7 0.0 0.39 10.3 0.0 1.8 1 0 0 1 1 1 0 Kelch motif Ribosomal_S2 PF00318.20 CDO76057.1 - 7e-28 97.3 0.1 3.8e-14 52.4 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CDO76057.1 - 3.3e-09 38.0 12.8 6.1e-09 37.1 12.8 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Glucosamine_iso PF01182.20 CDO76058.1 - 8.7e-09 35.6 0.0 0.00065 19.6 0.0 2.2 1 1 1 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.12 CDO76058.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain Pkinase PF00069.25 CDO76059.1 - 9.6e-63 212.0 0.1 5.3e-62 209.6 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76059.1 - 1.3e-36 126.2 0.0 8.8e-24 84.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDO76059.1 - 4.9e-05 22.8 0.0 8.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CDO76059.1 - 0.00038 20.5 8.5 0.028 14.3 0.2 3.5 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO76059.1 - 0.031 13.0 0.0 0.031 13.0 0.0 2.8 3 0 0 3 3 3 0 Fungal protein kinase Haspin_kinase PF12330.8 CDO76059.1 - 0.044 12.7 0.0 0.16 10.9 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain DUF2362 PF10154.9 CDO76059.1 - 0.21 10.5 7.3 0.43 9.5 7.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Sds3 PF08598.11 CDO76059.1 - 2.9 7.8 10.7 19 5.2 10.7 2.2 1 1 0 1 1 1 0 Sds3-like AAA_13 PF13166.6 CDO76059.1 - 5 5.6 13.3 7.3 5.1 13.3 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 CDO76059.1 - 8.9 5.8 10.9 16 5.0 10.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cytochrom_B561 PF03188.16 CDO76060.1 - 3.6e-13 49.8 3.6 3.6e-13 49.8 3.6 1.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 CDO76060.1 - 0.00037 20.6 5.6 0.54 10.4 3.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF4079) MFS_2 PF13347.6 CDO76060.1 - 0.0027 16.3 0.1 0.0027 16.3 0.1 1.9 1 1 1 2 2 2 1 MFS/sugar transport protein DUF2615 PF11027.8 CDO76060.1 - 0.003 17.7 1.4 4.8 7.4 0.0 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF2615) DUF2427 PF10348.9 CDO76060.1 - 0.006 16.4 4.7 0.006 16.4 4.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF4051 PF13260.6 CDO76060.1 - 0.17 11.6 3.5 0.1 12.3 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) PepSY_TM PF03929.16 CDO76060.1 - 0.19 11.4 5.4 0.14 11.8 2.9 2.0 1 1 0 1 1 1 0 PepSY-associated TM region BatD PF13584.6 CDO76060.1 - 0.23 10.2 0.1 0.35 9.6 0.1 1.2 1 0 0 1 1 1 0 Oxygen tolerance Phage_holin_3_6 PF07332.11 CDO76060.1 - 0.31 11.1 10.9 0.31 11.1 0.9 2.8 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4381 PF14316.6 CDO76060.1 - 0.96 9.7 0.0 0.96 9.7 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4381) Ni_hydr_CYTB PF01292.20 CDO76060.1 - 1.1 8.8 12.8 0.59 9.7 9.8 2.0 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4181 PF13789.6 CDO76060.1 - 4.1 7.7 7.0 1.4 9.2 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) FixQ PF05545.11 CDO76060.1 - 4.8 7.2 8.9 12 6.0 0.6 3.2 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Cytochrom_B561 PF03188.16 CDO76061.1 - 4.7e-12 46.2 3.0 8.6e-12 45.4 3.0 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 CDO76061.1 - 3e-11 43.3 2.1 6.4e-10 39.0 2.1 2.2 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 CDO76061.1 - 7.2e-06 26.2 0.2 1.6e-05 25.1 0.1 1.6 1 1 0 1 1 1 1 DOMON domain DUF4079 PF13301.6 CDO76061.1 - 0.0079 16.4 1.9 0.4 10.8 0.8 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF4079) DUF2427 PF10348.9 CDO76061.1 - 0.21 11.4 3.2 0.54 10.1 1.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Mg_trans_NIPA PF05653.14 CDO76062.1 - 1.5e-39 135.8 25.6 8.1e-28 97.4 6.7 3.1 3 0 0 3 3 3 3 Magnesium transporter NIPA Babuvirus_MP PF07234.11 CDO76062.1 - 1.2 9.3 6.5 6.3 7.0 1.0 2.6 2 0 0 2 2 2 0 Movement and RNA silencing protein SPC22 PF04573.12 CDO76064.1 - 6.6e-48 162.4 0.0 7.4e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Acyltransferase PF01553.21 CDO76065.1 - 1.6e-05 24.6 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase PP2C PF00481.21 CDO76066.1 - 1.6e-43 149.2 0.0 2.1e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.20 CDO76066.1 - 6e-23 81.4 0.0 1e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LytB_WW PF18342.1 CDO76066.1 - 0.18 12.0 0.1 0.73 10.0 0.0 2.1 2 0 0 2 2 2 0 Endo-beta-N-acetylglucosaminidase LytB WW domain LRR_8 PF13855.6 CDO76067.1 - 9.2e-50 166.3 49.8 3.8e-10 39.4 2.0 9.3 5 2 7 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 CDO76067.1 - 8.3e-45 150.0 52.8 2.6e-07 30.8 2.0 11.2 6 3 2 11 11 11 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDO76067.1 - 7.3e-13 48.4 19.1 3.7e-05 23.3 2.1 5.6 3 2 2 5 5 5 3 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 CDO76067.1 - 1.3e-05 24.8 0.2 1.3e-05 24.8 0.2 2.3 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 CDO76067.1 - 3.8e-05 23.6 53.0 0.47 11.2 1.3 14.9 14 2 1 15 15 15 2 Leucine Rich Repeat LRR_5 PF13306.6 CDO76067.1 - 0.00024 21.1 0.1 0.55 10.2 0.2 4.1 3 2 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) AlkA_N PF06029.11 CDO76067.1 - 0.1 12.9 0.4 0.98 9.7 0.0 2.6 2 1 1 3 3 3 0 AlkA N-terminal domain LRR_6 PF13516.6 CDO76067.1 - 2.8 8.2 45.5 1.4 9.1 0.2 12.3 15 1 0 15 15 15 0 Leucine Rich repeat rve PF00665.26 CDO76068.1 - 1.7e-12 47.6 0.0 3.1e-12 46.7 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CDO76068.1 - 0.03 14.1 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH_2 PF17919.1 CDO76069.1 - 5e-33 113.1 0.0 1.3e-32 111.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO76069.1 - 6.3e-32 110.0 0.0 1.3e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO76069.1 - 1.1e-27 97.0 0.0 1.8e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 CDO76069.1 - 0.053 12.9 0.1 1.1 8.6 0.0 2.7 3 0 0 3 3 3 0 DNA polymerase (viral) C-terminal domain RVP_2 PF08284.11 CDO76069.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Agglutinin_C PF18021.1 CDO76070.1 - 2.3e-38 130.6 0.2 3.4e-38 130.0 0.2 1.3 1 0 0 1 1 1 1 Agglutinin C-terminal Lectin_C_term PF18022.1 CDO76070.1 - 1.3e-35 121.9 0.1 1.8e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin C-terminal domain RVT_1 PF00078.27 CDO76071.1 - 7e-42 143.4 0.0 2.3e-41 141.7 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO76071.1 - 2.9e-18 66.4 0.1 8.5e-18 64.9 0.1 1.8 1 0 0 1 1 1 1 RNase H DUF445 PF04286.12 CDO76071.1 - 0.56 9.9 9.1 16 5.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF445) PBP1_TM PF14812.6 CDO76071.1 - 0.71 10.3 3.1 0.7 10.3 0.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AI-2E_transport PF01594.16 CDO76073.1 - 0.004 16.3 1.3 0.004 16.3 1.3 1.3 2 0 0 2 2 2 1 AI-2E family transporter TrbC PF04956.13 CDO76073.1 - 9.7 6.5 8.4 0.55 10.5 1.0 2.4 1 1 1 2 2 2 0 TrbC/VIRB2 family Myb_DNA-bind_3 PF12776.7 CDO76074.1 - 0.00015 22.7 0.1 0.00035 21.5 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO76074.1 - 0.00098 19.5 0.4 0.0027 18.0 0.2 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pap_E4 PF02711.14 CDO76074.1 - 9.5 7.3 7.1 11 7.0 2.2 2.7 2 1 0 2 2 2 0 E4 protein XPG_I PF00867.18 CDO76076.1 - 7.5e-18 64.7 0.0 1.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CDO76076.1 - 3.4e-05 24.2 0.0 7.7e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CDO76076.1 - 0.19 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing GPI-anchored PF10342.9 CDO76077.1 - 1.7e-06 28.7 0.0 2.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 CDO76077.1 - 0.033 14.0 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Kinesin PF00225.23 CDO76078.1 - 5.7e-82 275.3 0.0 4.8e-80 269.0 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDO76078.1 - 1.7e-21 76.7 0.0 3.7e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Pox_A_type_inc PF04508.12 CDO76078.1 - 1.2 9.1 6.8 1.8 8.6 3.9 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Arg_decarbox_C PF17944.1 CDO76078.1 - 6 7.5 6.3 2.1 9.0 0.3 3.2 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension GST_N_3 PF13417.6 CDO76079.1 - 2.3e-13 50.3 0.0 5.4e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO76079.1 - 2.7e-12 46.8 0.0 4.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO76079.1 - 4e-07 30.0 1.3 7.2e-07 29.2 0.4 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDO76079.1 - 3.6e-06 27.1 0.0 5.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO76079.1 - 0.0013 19.0 0.0 0.021 15.1 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CDO76079.1 - 0.0033 17.6 0.0 0.0063 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDO76080.1 - 1.5e-13 50.9 0.0 3.5e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO76080.1 - 2.5e-11 43.7 0.0 4.5e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO76080.1 - 1e-06 28.6 0.2 2.5e-06 27.4 0.2 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDO76080.1 - 0.0028 17.8 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO76080.1 - 0.0033 17.7 0.0 0.06 13.7 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 CDO76080.1 - 0.0098 16.2 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 CDO76080.1 - 0.019 15.2 0.1 0.054 13.7 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CDO76080.1 - 0.034 13.9 0.2 0.11 12.4 0.2 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CDO76080.1 - 0.071 13.9 0.0 0.36 11.6 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 CDO76081.1 - 8.4e-13 48.5 0.1 1.8e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO76081.1 - 9.1e-13 48.3 0.1 1.5e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO76081.1 - 8.9e-07 28.9 0.9 2e-06 27.7 0.3 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDO76081.1 - 0.00046 20.4 0.0 0.00074 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 CDO76081.1 - 0.021 15.1 0.0 0.036 14.4 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 CDO76081.1 - 0.065 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO76081.1 - 0.1 13.0 0.0 0.46 10.8 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO76082.1 - 2.6e-13 50.1 0.1 4.4e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CDO76082.1 - 1.2e-12 48.0 0.0 2.5e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO76082.1 - 7.8e-07 29.0 0.3 2.2e-06 27.6 0.3 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDO76082.1 - 0.00035 20.7 0.0 0.00057 20.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO76082.1 - 0.19 12.1 0.0 1.4 9.4 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ERG4_ERG24 PF01222.17 CDO76083.1 - 7.2e-140 466.5 2.6 8.8e-140 466.3 2.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 CDO76083.1 - 5.3e-05 23.6 1.7 0.00014 22.2 0.0 2.6 3 1 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 CDO76083.1 - 0.00021 20.9 0.1 0.0005 19.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 CDO76083.1 - 0.00069 20.0 0.1 0.0031 17.9 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1700 PF08006.11 CDO76083.1 - 0.074 12.6 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DMAP_binding PF06464.11 CDO76084.1 - 0.01 16.7 0.3 0.01 16.7 0.3 2.2 2 0 0 2 2 2 0 DMAP1-binding Domain Na_Ca_ex PF01699.24 CDO76085.1 - 4.3e-16 59.2 36.4 1.6e-11 44.4 12.6 3.9 4 1 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 CDO76085.1 - 1e-12 48.5 14.5 1e-12 48.5 14.5 3.9 3 0 0 3 3 3 1 Inner membrane component domain Otopetrin PF03189.13 CDO76085.1 - 0.0054 15.6 0.9 0.011 14.6 0.9 1.4 1 0 0 1 1 1 1 Otopetrin SLATT_5 PF18160.1 CDO76085.1 - 0.14 11.5 0.2 0.61 9.4 0.2 2.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 PgaD PF13994.6 CDO76085.1 - 5 7.2 7.3 16 5.6 0.0 2.9 3 0 0 3 3 3 0 PgaD-like protein CBFD_NFYB_HMF PF00808.23 CDO76086.1 - 1.3e-14 54.2 0.5 2.3e-14 53.4 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDO76086.1 - 9.6e-08 32.5 3.8 9.6e-08 32.5 3.8 1.7 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CDO76086.1 - 0.0031 17.5 0.1 0.0056 16.7 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 CDO76086.1 - 0.0074 16.4 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 CDO76086.1 - 0.48 10.5 2.0 0.36 10.9 0.2 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit MMS1_N PF10433.9 CDO76087.1 - 4.3e-59 200.5 0.0 6.7e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CDO76087.1 - 3.9e-42 144.7 0.0 7.4e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region TRAP-gamma PF07074.12 CDO76088.1 - 0.37 10.3 2.5 0.24 10.9 0.3 1.7 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Leader_Trp PF08255.11 CDO76089.1 - 3.3 7.9 8.3 16 5.8 0.1 2.9 2 0 0 2 2 2 0 Trp-operon Leader Peptide She9_MDM33 PF05546.11 CDO76090.1 - 5.3e-72 241.8 3.0 1e-71 240.9 3.0 1.4 1 0 0 1 1 1 1 She9 / Mdm33 family RPOL_N PF14700.6 CDO76090.1 - 0.044 13.2 3.2 0.095 12.1 3.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Mt_ATP-synt_B PF05405.14 CDO76090.1 - 0.076 12.6 3.5 0.24 11.0 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PulG PF11773.8 CDO76090.1 - 0.19 11.6 0.4 0.85 9.5 0.2 2.1 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin DUF948 PF06103.11 CDO76090.1 - 1.7 9.0 4.3 1.4 9.2 0.5 2.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FAD_binding_1 PF00667.20 CDO76091.1 - 3.4e-57 193.6 0.1 2.1e-56 191.0 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CDO76091.1 - 1.4e-30 106.4 0.9 1.8e-30 106.0 0.2 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CDO76091.1 - 2.1e-21 76.6 0.0 8.8e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SET PF00856.28 CDO76092.1 - 4.4e-06 27.2 0.0 5.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 SET domain Yae1_N PF09811.9 CDO76093.1 - 3e-11 42.8 1.7 3e-11 42.8 1.7 1.8 2 0 0 2 2 2 1 Essential protein Yae1, N terminal MtrG PF04210.13 CDO76093.1 - 0.0083 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4239 PF14023.6 CDO76093.1 - 0.027 14.2 0.0 0.09 12.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) PIN_6 PF17146.4 CDO76093.1 - 0.16 12.5 0.8 10 6.7 0.1 2.2 1 1 1 2 2 2 0 PIN domain of ribonuclease SpoIIIAH PF12685.7 CDO76093.1 - 0.43 10.4 4.6 0.86 9.4 4.7 1.3 1 1 0 1 1 1 0 SpoIIIAH-like protein cobW PF02492.19 CDO76094.1 - 2.9e-29 101.9 0.5 1.1e-28 100.0 0.5 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CDO76094.1 - 2.7e-06 27.2 0.0 5.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 CDO76094.1 - 0.19 11.6 0.0 8 6.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase DSPc PF00782.20 CDO76095.1 - 2.5e-28 98.5 0.0 3.3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CDO76095.1 - 0.025 14.6 0.1 0.072 13.1 0.1 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 CDO76095.1 - 0.038 14.3 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain UAA PF08449.11 CDO76096.1 - 3.9e-44 151.1 10.9 5.3e-44 150.6 10.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDO76096.1 - 9.6e-09 35.5 19.4 6.8e-07 29.5 11.1 3.5 3 1 0 3 3 3 2 EamA-like transporter family CRT-like PF08627.10 CDO76096.1 - 0.00026 20.0 5.9 0.071 12.0 0.2 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 CDO76096.1 - 0.00034 19.9 4.0 0.21 10.7 0.3 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter SLATT_4 PF18186.1 CDO76096.1 - 0.03 14.0 0.5 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 TPT PF03151.16 CDO76096.1 - 0.087 12.1 8.0 0.13 11.6 1.0 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family GTP_EFTU PF00009.27 CDO76098.1 - 2.9e-58 196.6 0.0 4.9e-58 195.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CDO76098.1 - 1.1e-16 60.7 0.0 2.4e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CDO76098.1 - 4.6e-07 29.8 0.0 1.2e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CDO76098.1 - 1.9e-05 25.0 0.0 4.6e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDO76098.1 - 8.1e-05 22.7 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.18 CDO76098.1 - 0.092 12.5 0.0 0.64 9.8 0.0 2.4 2 1 0 2 2 2 0 Elongation factor G, domain IV RasGEF PF00617.19 CDO76099.1 - 2.9e-49 167.6 1.8 5.2e-49 166.8 1.8 1.4 1 0 0 1 1 1 1 RasGEF domain SH3_1 PF00018.28 CDO76099.1 - 4.1e-17 61.5 0.1 1.3e-16 59.9 0.1 2.0 1 0 0 1 1 1 1 SH3 domain RasGEF_N PF00618.20 CDO76099.1 - 5.5e-17 61.9 0.1 1.3e-16 60.8 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 CDO76099.1 - 3.3e-14 52.5 0.3 5e-12 45.5 0.1 2.9 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 CDO76099.1 - 7e-10 38.4 0.0 2e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 CDO76099.1 - 1.1e-08 35.0 0.1 0.0025 17.8 0.1 2.5 2 0 0 2 2 2 2 WW domain Apolipoprotein PF01442.18 CDO76099.1 - 0.21 11.5 2.7 0.7 9.7 0.1 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Exo5 PF09810.9 CDO76100.1 - 4.1e-39 135.1 0.0 2.6e-37 129.2 0.0 2.7 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Pkinase_fungal PF17667.1 CDO76100.1 - 7.7e-12 44.7 0.0 6.5e-11 41.6 0.0 2.0 1 1 0 1 1 1 1 Fungal protein kinase CwfJ_C_2 PF04676.14 CDO76102.1 - 3.7e-37 127.2 0.7 2e-36 124.8 0.2 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 CDO76102.1 - 1.2e-31 109.1 0.0 1.8e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 AMP-binding PF00501.28 CDO76103.1 - 6.4e-43 146.9 0.0 6.4e-42 143.6 0.0 1.9 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CDO76103.1 - 9.5e-10 39.3 0.8 9.1e-09 36.2 0.2 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AhpC-TSA PF00578.21 CDO76104.1 - 2.6e-25 88.7 0.0 5.3e-24 84.5 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CDO76104.1 - 1e-15 57.7 0.1 2.5e-15 56.4 0.1 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 CDO76104.1 - 0.00092 19.3 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme zf-Tim10_DDP PF02953.15 CDO76105.1 - 3.7e-19 68.1 6.5 3.7e-19 68.1 6.5 1.5 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Tam41_Mmp37 PF09139.11 CDO76105.1 - 0.063 12.7 0.0 0.063 12.7 0.0 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial DAHP_synth_1 PF00793.20 CDO76106.1 - 8.5e-98 326.6 0.0 1.1e-97 326.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2615 PF11027.8 CDO76107.1 - 0.093 12.9 1.2 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) zf-CCHC PF00098.23 CDO76108.1 - 5e-05 23.2 2.1 5e-05 23.2 2.1 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-C2H2_10 PF16588.5 CDO76108.1 - 0.0031 17.2 2.2 0.0068 16.1 2.2 1.5 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_6 PF15288.6 CDO76108.1 - 0.039 13.8 0.3 0.09 12.6 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 CDO76108.1 - 0.046 14.0 0.1 0.085 13.1 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_4 PF14392.6 CDO76108.1 - 0.074 12.8 0.5 0.13 12.0 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_10 PF05971.12 CDO76109.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase HNH_2 PF13391.6 CDO76110.1 - 7.8e-06 25.9 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease LysM PF01476.20 CDO76111.1 - 0.00067 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain DUF4262 PF14081.6 CDO76112.1 - 0.062 13.5 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) DUF3072 PF11272.8 CDO76114.1 - 1.3e-05 25.0 0.3 0.054 13.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3072) ECH_1 PF00378.20 CDO76115.1 - 4.4e-82 275.2 0.1 5.5e-82 274.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CDO76115.1 - 2.1e-38 132.7 0.3 7.2e-33 114.5 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CDO76115.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 Peptidase family S49 Aminotran_1_2 PF00155.21 CDO76116.1 - 1.8e-16 60.3 0.0 2.4e-15 56.6 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II PQ-loop PF04193.14 CDO76118.1 - 2.7e-19 68.7 13.0 1.4e-10 40.7 0.3 3.1 3 0 0 3 3 3 2 PQ loop repeat Wzy_C PF04932.15 CDO76118.1 - 0.033 13.8 1.0 4.2 7.0 0.2 2.4 2 0 0 2 2 2 0 O-Antigen ligase MNHE PF01899.16 CDO76118.1 - 3.1 7.5 9.3 0.19 11.5 3.0 2.1 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit DUF4271 PF14093.6 CDO76119.1 - 2.8 7.8 13.8 0.039 13.9 3.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF5381 PF17353.2 CDO76119.1 - 6.5 6.5 8.1 3.4 7.4 1.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5381) DUF4271 PF14093.6 CDO76120.1 - 0.6 10.0 12.5 0.019 14.9 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Adap_comp_sub PF00928.21 CDO76121.1 - 1.4e-92 309.8 0.0 2.8e-92 308.8 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CDO76121.1 - 6.3e-07 29.4 0.3 1.1e-06 28.6 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RNase_PH PF01138.21 CDO76122.1 - 0.11 13.0 0.0 2.8 8.4 0.1 2.5 1 1 1 2 2 2 0 3' exoribonuclease family, domain 1 Spore_coat_CotO PF14153.6 CDO76122.1 - 0.28 11.1 7.1 0.52 10.2 7.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Transposase_21 PF02992.14 CDO76123.1 - 4.2e-11 42.5 0.0 1.6e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 SDA1 PF05285.12 CDO76123.1 - 0.041 13.3 12.4 0.061 12.7 12.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CDO76123.1 - 0.083 11.1 12.8 0.12 10.5 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family RPN1_RPN2_N PF17781.1 CDO76123.1 - 0.25 10.7 0.1 0.42 10.0 0.1 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain BUD22 PF09073.10 CDO76123.1 - 1.2 8.4 11.0 1.7 7.9 11.0 1.1 1 0 0 1 1 1 0 BUD22 RNA_polI_A34 PF08208.11 CDO76123.1 - 1.7 8.7 7.5 13 5.9 6.8 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 CobT PF06213.12 CDO76123.1 - 2.1 7.7 15.2 4.5 6.6 15.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YL1 PF05764.13 CDO76123.1 - 2.3 8.3 14.8 4 7.5 14.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 CDO76123.1 - 3.2 5.9 11.5 4.7 5.4 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 CDO76123.1 - 4.2 6.4 9.7 6.9 5.7 9.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TRAP_alpha PF03896.16 CDO76123.1 - 7.1 5.8 8.0 11 5.1 8.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 CDO76123.1 - 9 5.5 16.9 14 4.8 16.9 1.2 1 0 0 1 1 1 0 NOA36 protein Pro-kuma_activ PF09286.11 CDO76124.1 - 2.5e-44 151.0 0.1 8.2e-44 149.3 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO76124.1 - 0.02 14.2 0.3 0.06 12.6 0.3 1.6 1 1 0 1 1 1 0 Subtilase family Adenyl_cycl_N PF12633.7 CDO76124.1 - 0.043 13.7 0.0 5.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Adenylate cyclase NT domain DnaJ PF00226.31 CDO76125.1 - 2.1e-17 63.0 0.2 5.3e-17 61.7 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain LMBR1 PF04791.16 CDO76125.1 - 0.15 11.0 3.2 0.13 11.1 3.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ISG65-75 PF11727.8 CDO76125.1 - 3.6 6.7 24.3 6.2 6.0 24.3 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein DNA_pol_A_exo1 PF01612.20 CDO76126.1 - 7.6e-16 58.3 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease FA_desaturase PF00487.24 CDO76127.1 - 6.3e-25 88.5 32.4 9.4e-25 87.9 32.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 CDO76127.1 - 0.00061 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) ABC_tran PF00005.27 CDO76128.1 - 1e-27 97.3 0.1 1.7e-27 96.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CDO76128.1 - 1.5e-09 37.9 11.6 2e-09 37.5 11.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CDO76128.1 - 1.2e-05 24.8 1.2 0.0031 17.0 0.2 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 CDO76128.1 - 0.0012 19.0 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_25 PF13481.6 CDO76128.1 - 0.0015 18.2 0.1 0.0069 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CDO76128.1 - 0.0042 17.0 0.6 0.016 15.1 0.1 2.1 2 0 0 2 2 2 1 NTPase AAA_16 PF13191.6 CDO76128.1 - 0.0081 16.6 0.5 0.017 15.5 0.5 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CDO76128.1 - 0.0083 15.9 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CDO76128.1 - 0.009 16.1 0.1 0.019 15.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 CDO76128.1 - 0.015 15.1 1.1 1.2 8.9 0.3 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CDO76128.1 - 0.037 14.3 0.4 0.31 11.3 0.3 2.2 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 CDO76128.1 - 0.071 12.1 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DEAD PF00270.29 CDO76128.1 - 0.14 12.0 0.3 0.49 10.1 0.3 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_5 PF07728.14 CDO76128.1 - 0.14 12.2 0.1 2.5 8.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 CDO76128.1 - 0.16 11.0 2.1 0.47 9.5 0.0 2.6 4 0 0 4 4 4 0 Type II/IV secretion system protein AAA_23 PF13476.6 CDO76128.1 - 0.19 12.2 0.4 0.37 11.2 0.3 1.4 1 1 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 CDO76129.1 - 1e-15 58.1 14.5 1.6e-15 57.5 9.3 2.9 2 1 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 CDO76129.1 - 2e-12 47.8 0.4 5.2e-06 27.0 0.0 2.5 1 1 1 2 2 2 2 ABC transporter AAA_21 PF13304.6 CDO76129.1 - 2.9e-07 30.6 0.2 0.00012 22.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CDO76129.1 - 1.5e-05 24.6 0.0 0.14 11.6 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDO76129.1 - 3.3e-05 24.5 1.5 4.8e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CDO76129.1 - 0.0064 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 CDO76129.1 - 0.034 13.2 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 CDO76129.1 - 0.058 13.8 0.3 0.4 11.0 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 CDO76129.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CDO76129.1 - 0.084 13.1 0.1 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CDO76129.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CDO76129.1 - 0.11 12.0 0.1 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 CDO76129.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 CDO76129.1 - 0.15 11.6 0.1 0.6 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Med3 PF11593.8 CDO76129.1 - 1.7 7.7 4.4 2.7 7.1 4.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pro_isomerase PF00160.21 CDO76132.1 - 5e-49 166.6 0.1 7e-49 166.1 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CDO76132.1 - 6.5e-06 25.9 12.6 0.0025 17.8 0.6 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDO76132.1 - 1.4e-05 24.6 5.9 0.0069 16.2 0.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 CDO76132.1 - 0.00018 21.5 6.6 0.0014 18.6 0.1 2.5 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 CDO76132.1 - 0.00021 20.9 0.7 0.00021 20.9 0.7 2.8 3 0 0 3 3 3 1 TPR repeat DUF5113 PF17140.4 CDO76132.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) TPR_12 PF13424.6 CDO76132.1 - 0.032 14.5 9.4 1.4 9.2 1.5 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CDO76132.1 - 0.032 14.2 3.5 1.1 9.4 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDO76132.1 - 0.18 12.5 13.2 1.4 9.6 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDO76132.1 - 0.51 11.1 7.9 18 6.2 0.4 3.9 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CDO76132.1 - 0.9 10.1 8.9 13 6.4 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDO76132.1 - 1.2 10.1 7.4 9.8 7.3 3.1 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat RhoGAP PF00620.27 CDO76134.1 - 2.1e-10 40.6 0.0 3.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 CDO76134.1 - 0.0036 16.9 0.0 0.015 14.8 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HABP4_PAI-RBP1 PF04774.15 CDO76135.1 - 0.00035 21.4 2.2 0.00046 21.0 2.2 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Pkinase_fungal PF17667.1 CDO76136.1 - 8.5e-52 176.3 0.0 8.5e-51 173.0 0.0 2.4 1 1 0 1 1 1 1 Fungal protein kinase RVT_1 PF00078.27 CDO76137.1 - 3.8e-15 56.0 0.0 5.7e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO76137.1 - 1.3e-08 35.2 0.0 2.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO76137.1 - 0.001 19.7 0.0 0.0022 18.6 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase BTB PF00651.31 CDO76139.1 - 0.00013 22.2 0.0 0.00029 21.0 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Sod_Fe_C PF02777.18 CDO76142.1 - 1.4e-34 118.3 0.0 2.4e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CDO76142.1 - 1.8e-31 108.4 3.3 1.8e-31 108.4 3.3 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HET PF06985.11 CDO76143.1 - 4.1e-12 46.7 2.2 1.7e-09 38.1 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 CDO76144.1 - 1.3e-11 45.1 2.7 3.6e-09 37.1 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Dynamin_M PF01031.20 CDO76145.1 - 4.6e-34 117.9 0.0 4.1e-33 114.8 0.0 2.2 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CDO76145.1 - 7.4e-21 74.9 0.0 2.2e-20 73.4 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CDO76145.1 - 0.00025 21.1 0.2 0.0052 16.8 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 CDO76145.1 - 0.0094 16.1 0.0 0.054 13.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_21 PF13304.6 CDO76145.1 - 0.067 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CDO76145.1 - 0.098 13.0 0.3 1.3 9.4 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain PHD PF00628.29 CDO76146.1 - 1.7e-07 31.0 11.6 2.7e-07 30.4 11.6 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CDO76146.1 - 0.0039 16.7 7.8 0.0069 15.9 7.8 1.4 1 0 0 1 1 1 1 PHD-finger FAM76 PF16046.5 CDO76146.1 - 0.03 13.7 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 FAM76 protein SET PF00856.28 CDO76147.1 - 0.0031 17.9 0.2 0.036 14.4 0.0 2.4 3 0 0 3 3 3 1 SET domain Ribosomal_S17 PF00366.20 CDO76148.1 - 6.3e-21 74.3 0.4 9.2e-21 73.7 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Prefoldin_2 PF01920.20 CDO76149.1 - 1e-21 76.9 16.7 1.2e-21 76.6 16.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit End3 PF12761.7 CDO76149.1 - 0.0049 17.1 10.4 0.0063 16.7 10.4 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Prefoldin_3 PF13758.6 CDO76149.1 - 0.0068 16.4 5.4 0.0098 15.9 5.3 1.3 1 1 0 1 1 1 1 Prefoldin subunit Rx_N PF18052.1 CDO76149.1 - 0.008 16.4 10.6 0.29 11.4 1.6 2.6 1 1 1 2 2 2 2 Rx N-terminal domain Tup_N PF08581.10 CDO76149.1 - 0.0096 16.2 9.3 2.5 8.4 3.7 3.2 1 1 1 2 2 2 1 Tup N-terminal Prefoldin PF02996.17 CDO76149.1 - 0.023 14.6 10.5 0.023 14.6 3.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit APG6_N PF17675.1 CDO76149.1 - 0.067 13.7 16.2 0.07 13.6 4.9 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Tmpp129 PF10272.9 CDO76149.1 - 0.089 12.1 0.8 0.12 11.6 0.7 1.2 1 1 0 1 1 1 0 Putative transmembrane protein precursor NPV_P10 PF05531.12 CDO76149.1 - 0.12 12.9 10.3 1.6 9.3 0.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cluap1 PF10234.9 CDO76149.1 - 0.14 11.5 11.0 0.069 12.5 2.1 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 Spc24 PF08286.11 CDO76149.1 - 0.15 12.3 12.4 1.1 9.5 3.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Macoilin PF09726.9 CDO76149.1 - 0.17 10.4 9.2 0.2 10.2 9.2 1.1 1 0 0 1 1 1 0 Macoilin family Occludin_ELL PF07303.13 CDO76149.1 - 0.22 12.3 6.8 0.95 10.2 1.2 2.1 2 0 0 2 2 2 0 Occludin homology domain FlaC_arch PF05377.11 CDO76149.1 - 0.28 11.6 8.7 2.2 8.8 0.7 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) HalX PF08663.10 CDO76149.1 - 0.38 11.1 8.9 0.87 10.0 3.1 3.2 2 2 1 3 3 3 0 HalX domain ERM PF00769.19 CDO76149.1 - 0.48 10.2 12.3 0.74 9.6 12.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.7 CDO76149.1 - 0.85 9.8 14.6 0.79 9.9 3.5 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF5082 PF16888.5 CDO76149.1 - 0.89 9.8 10.0 5.1 7.4 9.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) KELK PF15796.5 CDO76149.1 - 0.89 10.0 11.0 0.58 10.7 1.7 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Chibby PF14645.6 CDO76149.1 - 0.92 9.9 5.6 0.43 11.0 0.8 2.1 1 1 1 2 2 2 0 Chibby family GAS PF13851.6 CDO76149.1 - 1 8.7 16.5 8.7 5.6 16.5 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding MCU PF04678.13 CDO76149.1 - 1.4 9.0 6.4 2.6 8.1 6.4 1.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter YabA PF06156.13 CDO76149.1 - 1.7 9.3 11.6 1.2 9.8 2.9 2.2 1 1 0 2 2 2 0 Initiation control protein YabA DMPK_coil PF08826.10 CDO76149.1 - 1.8 8.7 18.3 0.37 10.9 4.3 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF1664 PF07889.12 CDO76149.1 - 1.8 8.6 8.6 1.5 8.9 1.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 CDO76149.1 - 2.3 8.3 13.8 0.82 9.7 2.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 CDO76149.1 - 2.7 8.3 12.7 2.8 8.3 2.5 2.1 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 CDO76149.1 - 2.9 6.7 16.6 33 3.2 16.6 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 CDO76149.1 - 3.1 6.8 9.7 7 5.6 9.7 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlxA PF14282.6 CDO76149.1 - 5.1 7.1 15.4 0.96 9.5 4.4 2.3 2 0 0 2 2 2 0 FlxA-like protein UPF0242 PF06785.11 CDO76149.1 - 5.4 7.1 15.0 16 5.5 15.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus USP8_interact PF08941.10 CDO76149.1 - 5.6 6.7 8.0 1.6 8.5 2.9 1.9 1 1 1 2 2 2 0 USP8 interacting DUF724 PF05266.14 CDO76149.1 - 5.8 6.7 12.0 1.6e+02 2.0 12.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Osmo_CC PF08946.10 CDO76149.1 - 6.1 7.2 7.2 6.1 7.2 2.3 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF2203 PF09969.9 CDO76149.1 - 9 7.1 8.3 30 5.4 8.3 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.19 CDO76149.1 - 9.1 4.1 8.6 15 3.3 8.6 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Oxidored_molyb PF00174.19 CDO76150.1 - 2.3e-47 160.8 0.0 4.5e-47 159.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CDO76150.1 - 4.5e-28 98.0 0.1 1.3e-26 93.3 0.1 2.3 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 CDO76150.1 - 1e-20 73.9 0.0 2.1e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 CDO76150.1 - 1.9e-13 50.3 0.0 3.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 CDO76150.1 - 1.4e-12 48.2 0.0 3.3e-10 40.6 0.0 3.0 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain V-SNARE PF05008.15 CDO76151.1 - 0.00021 21.6 0.2 0.00094 19.5 0.1 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus UCR_TM PF02921.14 CDO76151.1 - 0.12 12.9 0.1 0.23 11.9 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region zf-RING_9 PF13901.6 CDO76153.1 - 0.036 14.0 2.6 0.071 13.1 2.6 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD PF00628.29 CDO76153.1 - 0.1 12.5 9.4 0.052 13.5 4.0 2.6 2 1 0 2 2 2 0 PHD-finger Nop10p PF04135.12 CDO76154.1 - 0.16 12.0 1.9 0.26 11.4 0.1 2.3 2 1 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Integrase_H2C2 PF17921.1 CDO76155.1 - 1.1e-17 63.9 2.3 2.3e-17 62.8 2.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CDO76155.1 - 5.1e-11 42.5 0.0 9.5e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDO76155.1 - 8.4e-09 35.7 0.0 3.7e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 CDO76155.1 - 1.8e-08 34.6 0.0 3.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GETHR PF05671.11 CDO76159.1 - 1 8.8 8.7 0.1 12.0 2.3 2.2 2 0 0 2 2 2 0 GETHR pentapeptide repeat (5 copies) Porin_3 PF01459.22 CDO76160.1 - 6.8e-74 248.7 2.3 7.7e-74 248.6 2.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rhodanese PF00581.20 CDO76161.1 - 4.4e-08 33.6 0.0 5.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF3767 PF12597.8 CDO76162.1 - 2.5e-16 59.3 0.0 3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) MEIOC PF15189.6 CDO76164.1 - 0.047 13.3 3.5 0.045 13.4 1.9 1.9 1 1 1 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC GST_C PF00043.25 CDO76170.1 - 2e-09 37.5 0.0 4.6e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO76170.1 - 8.8e-07 29.1 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO76170.1 - 5.3e-06 26.7 0.1 1.9e-05 24.9 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO76170.1 - 6.7e-05 22.8 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CDO76170.1 - 0.00051 20.4 0.0 0.00082 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO76170.1 - 0.021 15.1 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PEPCK_GTP PF00821.18 CDO76170.1 - 0.16 10.7 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain NAD_binding_4 PF07993.12 CDO76172.1 - 4.9e-28 98.0 0.0 7.2e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CDO76172.1 - 1.4e-10 41.1 0.0 6.7e-10 38.8 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CDO76172.1 - 1.6e-06 28.3 0.0 1.6e-05 25.2 0.0 2.6 2 1 0 2 2 2 1 Phosphopantetheine attachment site Gemini_AL1_M PF08283.11 CDO76172.1 - 0.033 14.3 0.4 1.2 9.3 0.0 3.1 3 1 1 4 4 4 0 Geminivirus rep protein central domain DUF956 PF06115.11 CDO76172.1 - 0.033 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF956) GDP_Man_Dehyd PF16363.5 CDO76172.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DcpS PF05652.12 CDO76172.1 - 0.11 13.3 0.0 0.41 11.5 0.0 1.9 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal AMP-binding PF00501.28 CDO76173.1 - 6.4e-30 104.1 0.0 1.9e-29 102.5 0.0 1.7 2 1 0 2 2 2 1 AMP-binding enzyme RVT_1 PF00078.27 CDO76175.1 - 1.4e-23 83.6 0.0 2.9e-22 79.3 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO76175.1 - 2.3e-20 73.3 0.0 4.9e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO76175.1 - 2.9e-05 24.7 1.2 2.9e-05 24.7 1.2 2.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CDO76176.1 - 0.00077 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.6 CDO76176.1 - 0.12 12.4 0.6 0.25 11.4 0.6 1.5 1 0 0 1 1 1 0 FlxA-like protein HeH PF12949.7 CDO76178.1 - 0.083 12.6 0.0 0.083 12.6 0.0 1.8 2 0 0 2 2 2 0 HeH/LEM domain EthD PF07110.11 CDO76180.1 - 1.3e-11 45.5 0.1 1.3e-11 45.5 0.1 3.4 2 1 0 2 2 2 1 EthD domain BRCT_2 PF16589.5 CDO76180.1 - 2.3e-08 34.3 0.0 5.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CDO76180.1 - 4.3e-05 23.8 0.0 8.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain MannoseP_isomer PF01050.18 CDO76180.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Usg PF06233.12 CDO76180.1 - 0.046 13.9 0.3 6.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Usg-like family Rap1-DNA-bind PF09197.10 CDO76180.1 - 0.45 11.1 7.4 19 5.9 3.0 3.3 3 0 0 3 3 3 0 Rap1, DNA-binding EthD PF07110.11 CDO76181.1 - 4.8e-14 53.3 0.3 6.5e-14 52.8 0.3 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 CDO76181.1 - 0.0059 17.0 0.0 0.0064 16.9 0.0 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase PhyH PF05721.13 CDO76182.1 - 1.9e-23 83.9 0.0 2.4e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HK PF02110.15 CDO76183.1 - 1.4e-72 244.0 1.2 1.7e-67 227.4 2.1 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 CDO76183.1 - 4.9e-54 182.4 0.2 1.1e-53 181.3 0.2 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase IMPDH PF00478.25 CDO76183.1 - 0.035 13.1 3.1 2.1 7.3 1.2 2.3 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Peptidase_M19 PF01244.21 CDO76183.1 - 0.069 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) TPMT PF05724.11 CDO76184.1 - 5.4e-34 117.8 0.0 8.7e-34 117.1 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 CDO76184.1 - 3.9e-10 40.3 0.0 5.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO76184.1 - 1.2e-09 38.1 0.0 1.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO76184.1 - 6.7e-08 33.2 0.0 9.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO76184.1 - 7.5e-07 29.7 0.0 1.1e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO76184.1 - 0.00098 19.0 0.0 0.0015 18.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CDO76184.1 - 0.0032 16.9 0.0 0.0079 15.6 0.0 1.6 1 1 1 2 2 2 1 Tellurite resistance protein TehB CMAS PF02353.20 CDO76184.1 - 0.004 16.5 0.0 0.0054 16.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 CDO76184.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SUR7 PF06687.12 CDO76185.1 - 1e-11 44.9 11.7 1.5e-10 41.1 11.7 2.1 1 1 0 1 1 1 1 SUR7/PalI family HRG PF16954.5 CDO76185.1 - 0.12 12.8 0.7 0.12 12.8 0.7 3.4 4 0 0 4 4 4 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF747 PF05346.11 CDO76187.1 - 1.2e-89 301.0 0.8 9.6e-79 265.1 0.1 2.2 1 1 1 2 2 2 2 Eukaryotic membrane protein family SMC_hinge PF06470.13 CDO76188.1 - 1.3e-25 90.0 0.4 5.7e-25 87.9 0.0 2.4 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 CDO76188.1 - 4.7e-22 78.5 27.6 6.7e-21 74.7 27.6 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF3606 PF12244.8 CDO76188.1 - 0.02 14.8 1.8 0.036 14.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) LPP PF04728.13 CDO76188.1 - 0.31 11.5 19.6 9 6.8 0.1 6.3 4 1 2 6 6 6 0 Lipoprotein leucine-zipper BLOC1_2 PF10046.9 CDO76188.1 - 0.75 10.1 50.0 1.4 9.3 4.1 8.2 6 3 1 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_21 PF13304.6 CDO76188.1 - 1.3 8.7 0.0 1.3 8.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Baculo_PEP_C PF04513.12 CDO76188.1 - 1.6 8.8 29.6 1.2 9.1 1.1 6.3 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 CDO76188.1 - 4.2 7.9 120.0 5.2 7.6 17.1 7.6 3 2 3 6 6 6 0 Apg6 coiled-coil region RrnaAD PF00398.20 CDO76189.1 - 3e-06 26.5 0.0 4.1e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Mcl1_mid PF12341.8 CDO76190.1 - 1.2e-53 182.4 1.0 5.2e-30 104.8 0.0 3.0 2 1 1 3 3 3 2 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 CDO76190.1 - 1.6e-16 60.4 8.1 2.2e-05 25.1 0.3 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO76190.1 - 9.6e-13 48.2 0.1 0.0095 16.2 0.0 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO76190.1 - 0.024 13.6 0.0 1.7 7.6 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CDO76190.1 - 0.039 13.9 0.0 12 6.0 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DAG1 PF05454.11 CDO76190.1 - 0.04 13.3 0.3 0.07 12.5 0.3 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) PSII_BNR PF14870.6 CDO76190.1 - 0.07 12.4 0.4 0.15 11.3 0.2 1.6 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 Glyco_hydro_61 PF03443.14 CDO76191.1 - 3.5e-62 210.0 0.0 4.2e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TatD_DNase PF01026.21 CDO76192.1 - 9.8e-47 159.5 0.5 1.2e-46 159.1 0.5 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 CDO76192.1 - 0.0012 18.7 0.2 0.0065 16.3 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.11 CDO76192.1 - 0.042 13.3 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase family ALAD PF00490.21 CDO76193.1 - 5.1e-125 416.9 0.0 6e-125 416.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CPSF73-100_C PF11718.8 CDO76194.1 - 1.6e-65 220.7 0.1 2.4e-65 220.1 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CDO76194.1 - 6.6e-28 97.2 0.0 1.8e-27 95.8 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CDO76194.1 - 2.5e-18 66.2 0.0 8.9e-18 64.4 0.0 2.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CDO76194.1 - 6.5e-17 61.2 0.1 1.5e-16 60.0 0.1 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CDO76194.1 - 8.5e-17 61.8 0.7 3.5e-16 59.8 0.6 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 CDO76194.1 - 1.8e-06 28.0 0.1 1e-05 25.5 0.1 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CDO76194.1 - 4e-06 26.5 2.1 4.1e-06 26.5 0.6 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF2264 PF10022.9 CDO76195.1 - 5.1e-140 466.6 0.1 6.1e-140 466.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Transposase_21 PF02992.14 CDO76200.1 - 9.5e-11 41.3 0.0 6.4e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 CDO76200.1 - 0.012 15.2 0.1 0.05 13.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) PI3K_1B_p101 PF10486.9 CDO76201.1 - 0.03 12.1 3.6 0.049 11.4 3.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nop14 PF04147.12 CDO76201.1 - 2.2 6.4 36.7 2.7 6.1 36.7 1.2 1 0 0 1 1 1 0 Nop14-like family SGL PF08450.12 CDO76202.1 - 4e-25 88.8 0.0 7.1e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 CDO76202.1 - 8.6e-07 29.0 0.0 2.8e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 CDO76202.1 - 0.00028 21.0 0.0 0.00073 19.7 0.0 1.7 1 0 0 1 1 1 1 Arylesterase F-box-like PF12937.7 CDO76203.1 - 2.5e-06 27.3 0.0 8.2e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 F-box-like PhoLip_ATPase_C PF16212.5 CDO76204.1 - 1.9e-76 257.1 30.1 1.9e-76 257.1 30.1 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CDO76204.1 - 3.8e-22 77.7 0.1 3.8e-22 77.7 0.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CDO76204.1 - 1.9e-12 47.9 0.3 1.4e-07 32.0 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDO76204.1 - 1e-11 44.7 0.0 2.5e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CDO76204.1 - 1.9e-05 24.3 0.0 1.9e-05 24.3 0.0 3.4 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CDO76204.1 - 0.0019 18.0 0.1 0.046 13.5 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Asp PF00026.23 CDO76205.1 - 6.3e-19 68.5 0.0 4.9e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO76205.1 - 9.9e-05 22.6 0.1 0.0004 20.7 0.0 2.0 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Fungal_trans PF04082.18 CDO76206.1 - 1.9e-23 82.9 0.0 3.5e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4175 PF13779.6 CDO76206.1 - 3.1 5.6 9.1 4.7 5.0 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mito_carr PF00153.27 CDO76207.1 - 1.8e-54 181.6 0.6 4.4e-17 61.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3967 PF13152.6 CDO76207.1 - 0.11 12.3 0.4 19 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) DUF957 PF06117.11 CDO76207.1 - 0.21 11.2 0.0 0.52 9.9 0.0 1.6 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) Ferric_reduct PF01794.19 CDO76208.1 - 8.1e-19 68.0 6.5 2.4e-18 66.4 6.5 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CDO76208.1 - 6.3e-16 58.9 0.0 1.1e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CDO76208.1 - 3.1e-14 53.0 0.0 4.8e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain WBP-1 PF11669.8 CDO76208.1 - 0.055 14.1 0.0 9.5 6.9 0.0 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 NAD_binding_6 PF08030.12 CDO76209.1 - 8e-21 74.8 0.0 1.4e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CDO76209.1 - 8.6e-15 54.8 0.0 1.8e-10 40.8 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.19 CDO76209.1 - 0.00066 19.8 3.6 0.0014 18.8 3.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component VGCC_beta4Aa_N PF12052.8 CDO76209.1 - 0.56 10.4 2.1 13 5.9 0.1 2.5 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Pyr_redox_2 PF07992.14 CDO76210.1 - 7.1e-50 169.9 0.0 9.3e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDO76210.1 - 1.5e-10 41.5 0.1 4.9e-08 33.4 0.0 3.5 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CDO76210.1 - 0.053 12.8 0.0 5 6.3 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CDO76210.1 - 0.097 13.1 0.0 1.3 9.5 0.0 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.14 CDO76210.1 - 0.17 10.6 0.5 0.62 8.7 0.0 2.0 1 1 1 2 2 2 0 HI0933-like protein RVT_2 PF07727.14 CDO76211.1 - 4.2e-81 272.2 0.2 6.3e-81 271.6 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO76211.1 - 1.9e-21 76.5 0.0 4.9e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDO76211.1 - 0.00017 21.3 0.1 0.00043 20.0 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain Mem_trans PF03547.18 CDO76212.1 - 3.2e-12 45.5 1.4 4.3e-09 35.3 0.0 2.5 3 0 0 3 3 3 2 Membrane transport protein RVT_1 PF00078.27 CDO76213.1 - 0.029 13.9 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Trs65 PF12735.7 CDO76214.1 - 6.9e-12 45.4 0.1 7.2e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 TRAPP trafficking subunit Trs65 DUF4880 PF16220.5 CDO76214.1 - 0.15 11.9 1.7 0.44 10.5 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Plavaka PF18759.1 CDO76216.1 - 3.3e-24 85.7 0.0 8.1e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Plavaka transposase MULE PF10551.9 CDO76217.1 - 7.6e-09 35.9 0.0 1.8e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain His_Me_b4a2 PF18275.1 CDO76217.1 - 0.02 14.9 0.1 0.047 13.8 0.1 1.6 1 0 0 1 1 1 0 His-Me finger endonuclease beta4-alpha2 domain SWIM PF04434.17 CDO76217.1 - 0.065 12.9 0.3 0.14 11.8 0.3 1.6 1 0 0 1 1 1 0 SWIM zinc finger Snf7 PF03357.21 CDO76217.1 - 0.1 12.2 0.3 0.2 11.2 0.3 1.5 1 0 0 1 1 1 0 Snf7 SIMPL PF04402.14 CDO76217.1 - 0.17 12.3 0.2 0.39 11.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF541) HET PF06985.11 CDO76218.1 - 4.6e-10 40.0 0.8 2.8e-07 31.0 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PTCB-BRCT PF12738.7 CDO76219.1 - 3.9e-27 94.0 4.1 1.5e-16 60.1 0.3 6.0 6 0 0 6 6 6 2 twin BRCT domain BRCT_2 PF16589.5 CDO76219.1 - 8.5e-21 74.2 0.0 1.6e-06 28.4 0.0 4.8 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CDO76219.1 - 6.1e-20 71.4 0.0 4.8e-08 33.3 0.1 5.4 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 CDO76219.1 - 1.3e-13 50.7 0.0 9.5e-11 41.5 0.0 3.2 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 CDO76219.1 - 2e-09 37.6 0.3 0.0025 18.1 0.0 4.7 5 0 0 5 5 5 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 CDO76219.1 - 0.047 13.8 0.0 0.4 10.8 0.0 2.6 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.25 CDO76220.1 - 1.9e-70 237.2 0.0 2.8e-70 236.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76220.1 - 1e-37 129.9 0.0 1.7e-37 129.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CDO76220.1 - 2.6e-16 59.7 0.1 4.6e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 FHA domain APH PF01636.23 CDO76220.1 - 2.7e-05 24.2 0.0 0.0015 18.5 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDO76220.1 - 6.4e-05 22.4 0.0 9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDO76220.1 - 0.00025 20.4 0.0 0.00052 19.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CDO76221.1 - 7.3e-42 143.6 0.0 6.1e-29 101.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76221.1 - 1.3e-15 57.3 0.0 3.7e-10 39.5 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 CDO76221.1 - 2.3e-13 50.3 0.0 4.8e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 CDO76221.1 - 0.00044 20.4 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CDO76221.1 - 0.0009 19.5 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 CDO76221.1 - 0.041 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDO76222.1 - 5.5e-57 193.1 0.0 8.3e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76222.1 - 4.6e-34 117.9 0.0 1.3e-33 116.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CDO76222.1 - 3.7e-11 43.2 1.2 1.2e-09 38.4 1.2 2.5 1 1 0 1 1 1 1 FHA domain APH PF01636.23 CDO76222.1 - 2.7e-06 27.5 0.6 4.4e-05 23.5 0.6 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDO76222.1 - 6.1e-05 22.5 0.2 0.00011 21.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 CDO76222.1 - 0.0016 18.7 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain RIO1 PF01163.22 CDO76222.1 - 0.0028 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CDO76222.1 - 0.022 13.7 0.1 0.03 13.3 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CDO76222.1 - 0.072 12.7 0.1 14 5.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 GlyL_C PF12524.8 CDO76223.1 - 0.34 11.1 8.1 0.16 12.1 1.2 2.4 2 0 0 2 2 2 0 dsDNA virus glycoprotein L C terminal Glyoxalase PF00903.25 CDO76225.1 - 2.5e-22 79.4 0.0 4.5e-22 78.6 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 CDO76225.1 - 3e-06 28.0 0.0 1.2e-05 26.0 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 CDO76225.1 - 2.5e-05 24.5 0.0 6.7e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CDO76225.1 - 0.021 15.0 0.0 0.061 13.4 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase-like domain Glyoxalase_2 PF12681.7 CDO76225.1 - 0.17 11.8 0.0 3.3 7.7 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase-like domain DUF4246 PF14033.6 CDO76227.1 - 4.5e-49 167.8 0.0 6.1e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) PLDc PF00614.22 CDO76228.1 - 6.1e-16 57.9 7.8 6.9e-09 35.5 0.2 2.7 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CDO76228.1 - 1.9e-15 57.0 0.4 3.6e-07 30.1 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain Prenyltrans PF00432.21 CDO76229.1 - 6e-08 32.3 0.0 6e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat HP1451_C PF18472.1 CDO76229.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 HP1451 C-terminal domain Prenyltrans PF00432.21 CDO76230.1 - 6.2e-07 29.0 1.6 0.00028 20.6 0.2 2.5 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat Tox-GHH PF15636.6 CDO76230.1 - 0.001 19.0 1.0 0.0085 16.0 1.0 2.3 1 1 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin F-box-like PF12937.7 CDO76231.1 - 9e-12 44.7 0.8 9e-12 44.7 0.8 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 CDO76231.1 - 0.00023 20.9 0.6 0.00081 19.2 0.6 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 CDO76232.1 - 0.031 14.7 3.1 2.1e+02 2.6 1.0 5.9 4 3 3 7 7 7 0 Leucine Rich repeats (2 copies) EBV-NA1 PF02905.14 CDO76232.1 - 0.084 12.7 0.6 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain p450 PF00067.22 CDO76234.1 - 3.4e-62 210.7 0.0 1.2e-47 162.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 RVT_2 PF07727.14 CDO76235.1 - 9.3e-68 228.5 0.0 1.5e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CDO76235.1 - 6.6e-22 77.7 0.0 2.6e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type rve PF00665.26 CDO76235.1 - 4.1e-16 59.2 0.2 6.4e-15 55.4 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 CDO76235.1 - 0.00014 21.7 0.0 0.00034 20.4 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain Plavaka PF18759.1 CDO76236.1 - 2.5e-109 365.5 0.1 3.5e-109 365.0 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase Leo1 PF04004.13 CDO76236.1 - 0.019 14.8 0.2 0.039 13.8 0.2 1.4 1 0 0 1 1 1 0 Leo1-like protein Sugar_tr PF00083.24 CDO76237.1 - 6.9e-32 110.9 26.6 1.9e-31 109.4 26.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO76237.1 - 2.5e-31 108.9 33.3 2.5e-31 108.9 33.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 CDO76237.1 - 0.0013 17.6 11.4 0.0021 16.9 11.4 1.3 1 0 0 1 1 1 1 LacY proton/sugar symporter MtrF PF09472.10 CDO76237.1 - 1.3 8.5 3.9 1.8 8.0 0.6 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) GNAT_acetyltr_2 PF13718.6 CDO76238.1 - 2.6e-93 311.6 0.0 4.8e-93 310.8 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CDO76238.1 - 2.6e-80 269.5 0.1 4.6e-80 268.7 0.1 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CDO76238.1 - 1.7e-63 213.7 0.0 1.7e-63 213.7 0.0 2.2 3 0 0 3 3 3 1 Helicase DUF1726 PF08351.11 CDO76238.1 - 5.1e-32 109.7 0.0 1.2e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 CDO76238.1 - 0.008 16.4 0.3 0.16 12.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain Acetyltransf_7 PF13508.7 CDO76238.1 - 0.086 13.3 0.0 0.46 10.9 0.0 2.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IBR PF01485.21 CDO76239.1 - 0.078 13.2 0.8 0.17 12.2 0.8 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain RPAP2_Rtr1 PF04181.13 CDO76239.1 - 0.49 10.7 2.3 2.2 8.7 2.3 2.0 1 1 0 1 1 1 0 Rtr1/RPAP2 family GTP_CH_N PF12471.8 CDO76240.1 - 1.6e-92 308.6 0.0 2.4e-92 308.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 CDO76240.1 - 1e-11 44.7 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribonuclease_3 PF00636.26 CDO76241.1 - 1.3e-39 135.0 0.0 1e-20 74.3 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 CDO76241.1 - 3.5e-24 84.8 0.1 9.2e-23 80.2 0.0 2.9 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 CDO76241.1 - 9e-22 77.6 0.1 7.6e-07 29.3 0.0 4.7 4 0 0 4 4 4 4 Ribonuclease-III-like DEAD PF00270.29 CDO76241.1 - 2.5e-16 60.0 0.0 6.5e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO76241.1 - 1.5e-14 54.3 0.0 3.3e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO76241.1 - 3.3e-13 50.0 0.0 7.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ion_trans_2 PF07885.16 CDO76242.1 - 2.7e-11 43.2 3.2 2.7e-11 43.2 3.2 2.3 1 1 1 2 2 2 1 Ion channel Ion_trans PF00520.31 CDO76242.1 - 1.2e-05 24.7 9.0 0.022 14.0 0.1 2.1 1 1 1 2 2 2 2 Ion transport protein Lig_chan PF00060.26 CDO76242.1 - 0.0076 16.1 1.0 0.022 14.6 1.0 1.8 1 1 0 1 1 1 1 Ligand-gated ion channel RVT_1 PF00078.27 CDO76243.1 - 2e-36 125.6 0.0 3.2e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO76243.1 - 3.4e-09 37.0 0.0 1.1e-08 35.3 0.0 1.9 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 CDO76243.1 - 0.0044 17.7 0.1 0.012 16.3 0.1 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DAO PF01266.24 CDO76244.1 - 1.1e-57 196.2 0.0 1.4e-57 195.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 CDO76244.1 - 6.7e-07 28.2 0.0 0.018 13.6 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 CDO76244.1 - 0.00024 20.4 0.1 0.012 14.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO76244.1 - 0.00027 21.1 0.1 0.00054 20.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CDO76244.1 - 0.0016 19.0 0.0 0.025 15.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CDO76244.1 - 0.12 11.4 0.0 0.56 9.2 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 CDO76244.1 - 0.14 12.2 0.1 0.46 10.5 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding NDUFA12 PF05071.16 CDO76245.1 - 1.3e-34 118.9 6.5 2e-34 118.3 6.5 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF2322 PF10084.9 CDO76245.1 - 0.094 12.8 0.0 0.88 9.7 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) Abhydrolase_1 PF00561.20 CDO76246.1 - 3.9e-19 69.3 0.0 2.1e-18 66.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO76246.1 - 4.1e-13 49.1 0.0 1.7e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO76246.1 - 5.2e-12 46.8 0.3 7.6e-12 46.3 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CDO76246.1 - 0.0015 18.2 0.0 0.97 9.0 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 CDO76246.1 - 0.053 13.6 0.0 0.097 12.8 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain His_biosynth PF00977.21 CDO76247.1 - 3e-34 118.5 0.0 3.9e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein GNAT_like PF18407.1 CDO76247.1 - 0.021 15.1 1.7 2.9 8.3 0.4 2.6 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain nos_propeller PF18764.1 CDO76247.1 - 0.057 13.3 0.1 6.3 6.8 0.0 2.7 1 1 2 3 3 3 0 Nitrous oxide reductase propeller repeat Fe-ADH PF00465.19 CDO76248.1 - 5.9e-89 298.4 0.0 7.5e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CDO76248.1 - 1.1e-10 41.7 0.0 2.1e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Asp PF00026.23 CDO76249.1 - 7.4e-29 101.2 0.4 9.9e-28 97.5 0.4 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO76249.1 - 1.4e-06 28.7 2.1 0.0018 18.5 0.0 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO76249.1 - 0.0042 17.7 0.1 0.36 11.5 0.1 2.8 2 1 0 2 2 2 1 Aspartyl protease PPR_2 PF13041.6 CDO76250.1 - 3.1e-18 65.7 0.0 1.2e-10 41.4 0.0 4.9 5 1 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 CDO76250.1 - 4.3e-11 42.7 0.0 1.2e-06 28.5 0.0 3.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 CDO76250.1 - 3.7e-09 36.2 0.0 0.0022 18.1 0.0 5.5 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 CDO76250.1 - 8.9e-08 31.7 0.0 0.0049 16.3 0.0 3.0 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CDO76250.1 - 8.2e-07 28.6 0.0 0.9 9.3 0.0 4.6 4 0 0 4 4 4 2 PPR repeat TPR_19 PF14559.6 CDO76250.1 - 0.0097 16.4 0.3 0.093 13.3 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDO76250.1 - 0.035 14.9 4.5 1.1 10.3 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Mur_ligase_M PF08245.12 CDO76251.1 - 1.2e-06 28.7 0.0 0.0016 18.4 0.0 3.3 2 1 1 3 3 3 2 Mur ligase middle domain DUF1421 PF07223.11 CDO76251.1 - 0.14 12.0 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Slx4 PF09494.10 CDO76252.1 - 4.1e-07 29.9 0.0 8.7e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease DAAD PF18752.1 CDO76253.1 - 0.061 13.2 0.2 0.067 13.0 0.2 1.1 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase IBN_N PF03810.19 CDO76254.1 - 4.7e-14 52.1 0.0 2.6e-11 43.3 0.0 3.0 2 0 0 2 2 2 2 Importin-beta N-terminal domain Xpo1 PF08389.12 CDO76254.1 - 0.0024 18.0 0.1 0.012 15.7 0.1 2.2 1 0 0 1 1 1 1 Exportin 1-like protein HEAT_2 PF13646.6 CDO76254.1 - 0.092 13.1 4.8 0.56 10.6 0.4 3.8 4 0 0 4 4 4 0 HEAT repeats CDC27 PF09507.10 CDO76255.1 - 2.8e-07 30.3 80.0 6.6e-06 25.8 80.0 2.5 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 TonB_N PF16031.5 CDO76255.1 - 0.017 15.7 24.0 0.017 15.7 24.0 5.1 1 1 3 5 5 5 0 TonB polyproline region POPLD PF08170.12 CDO76255.1 - 0.13 12.6 0.6 0.48 10.8 0.6 2.1 1 0 0 1 1 1 0 POPLD (NUC188) domain Pex2_Pex12 PF04757.14 CDO76256.1 - 3e-22 79.3 8.9 6.6e-14 52.0 5.8 2.2 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 CDO76256.1 - 1.8e-05 24.6 1.7 4.6e-05 23.3 0.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CDO76256.1 - 0.00058 19.8 0.2 0.0027 17.7 0.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CDO76256.1 - 0.00062 19.6 2.2 0.0041 17.0 2.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDO76256.1 - 0.00071 19.4 1.4 0.0027 17.5 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO76256.1 - 0.017 15.4 2.3 0.18 12.2 0.4 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 CDO76256.1 - 0.026 14.7 1.4 0.026 14.7 1.4 1.9 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CDO76256.1 - 0.049 13.5 0.8 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CDO76256.1 - 0.27 11.1 6.0 1.3 9.0 3.1 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RDD PF06271.12 CDO76256.1 - 0.34 11.1 2.1 2 8.6 2.1 2.0 1 1 0 1 1 1 0 RDD family zf-RING_11 PF17123.5 CDO76256.1 - 7 6.5 5.7 17 5.3 1.1 2.4 2 0 0 2 2 2 0 RING-like zinc finger tRNA-synt_2d PF01409.20 CDO76257.1 - 4.1e-84 281.9 0.0 1.5e-55 188.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 CDO76257.1 - 3.9e-18 65.5 0.7 3.9e-18 65.5 0.7 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 CDO76257.1 - 3e-10 39.9 0.0 2.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 CDO76257.1 - 0.0013 17.9 0.2 0.023 13.8 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 CDO76257.1 - 0.0048 16.9 0.2 0.0048 16.9 0.2 2.6 3 0 0 3 3 3 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 CDO76257.1 - 0.0071 16.3 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD1 PF18552.1 CDO76257.1 - 0.15 11.9 0.2 1.6 8.6 0.2 2.3 1 1 0 1 1 1 0 PheRS DNA binding domain 1 ThrE PF06738.12 CDO76258.1 - 2.8e-46 157.9 8.8 2.8e-46 157.9 8.8 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CDO76258.1 - 0.00052 20.2 10.9 0.00052 20.2 10.9 2.9 3 1 0 3 3 3 1 Threonine/Serine exporter, ThrE CENP-B_dimeris PF09026.10 CDO76258.1 - 5.1 7.6 9.6 11 6.4 9.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Acetyltransf_1 PF00583.25 CDO76259.1 - 3e-13 50.0 0.0 7.5e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO76259.1 - 5e-10 39.7 0.0 3.5e-09 37.0 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDO76259.1 - 1.1e-09 38.3 0.0 2.8e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CDO76259.1 - 5.2e-07 30.4 0.0 2e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDO76259.1 - 6.1e-07 29.3 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 CDO76259.1 - 0.0093 15.7 0.0 0.025 14.3 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDO76259.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 CDO76259.1 - 0.03 14.5 0.0 0.063 13.4 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 CDO76259.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase DUF454 PF04304.13 CDO76260.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DUF2370 PF10176.9 CDO76262.1 - 2.5e-76 256.3 0.0 4.5e-76 255.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Pkinase PF00069.25 CDO76263.1 - 1.8e-06 27.5 0.0 0.0002 20.8 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76263.1 - 0.0037 16.6 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-met PF12874.7 CDO76264.1 - 3.6e-21 74.8 27.3 0.0004 20.7 0.6 7.8 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CDO76264.1 - 2e-19 68.9 42.1 0.01 16.2 0.6 8.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CDO76264.1 - 9.3e-19 67.2 27.6 1.3e-06 28.5 0.3 7.4 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CDO76264.1 - 6e-18 64.0 36.5 0.045 14.6 0.4 9.0 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CDO76264.1 - 5.8e-07 29.8 26.1 0.0017 18.6 8.8 4.3 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CDO76264.1 - 0.0014 18.4 28.8 0.35 10.7 0.0 6.7 7 0 0 7 7 7 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CDO76264.1 - 0.0076 16.2 35.0 0.01 15.8 0.6 7.4 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2H2_9 PF16293.5 CDO76264.1 - 0.11 12.4 0.3 0.11 12.4 0.3 4.4 4 2 2 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-LYAR PF08790.11 CDO76264.1 - 0.31 11.0 0.1 0.31 11.0 0.1 4.8 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 CDO76264.1 - 0.41 11.1 0.0 0.41 11.1 0.0 4.2 3 3 1 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 CDO76264.1 - 0.79 10.3 0.0 0.79 10.3 0.0 7.3 8 0 0 8 8 8 0 Zinc-finger double domain Actin_micro PF17003.5 CDO76264.1 - 2.4 7.2 8.0 0.21 10.7 2.8 2.0 3 0 0 3 3 3 0 Putative actin-like family FOXP-CC PF16159.5 CDO76264.1 - 9.1 7.0 0.0 9.1 7.0 0.0 6.0 3 1 4 7 7 7 0 FOXP coiled-coil domain Cactin_mid PF10312.9 CDO76265.1 - 5.7e-66 222.0 6.6 5.7e-66 222.0 6.6 2.8 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 CDO76265.1 - 1.2e-58 196.5 3.9 3e-58 195.2 3.9 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein tRNA_synthFbeta PF17759.1 CDO76265.1 - 3.4e-49 167.2 0.0 6.3e-49 166.3 0.0 1.5 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 CDO76265.1 - 1.2e-28 99.9 0.1 3e-28 98.7 0.1 1.7 1 0 0 1 1 1 1 B3/4 domain PhetRS_B1 PF18262.1 CDO76265.1 - 1.7e-28 98.7 0.1 8.1e-28 96.5 0.0 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 CDO76265.1 - 5.1e-19 68.3 0.0 4.8e-15 55.6 0.0 2.9 2 0 0 2 2 2 2 tRNA synthetase B5 domain SF3A2 PF16835.5 CDO76265.1 - 0.039 14.3 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) AAA_2 PF07724.14 CDO76266.1 - 4.1e-31 108.4 0.0 8.2e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CDO76266.1 - 8.5e-12 45.6 0.0 1.7e-11 44.7 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CDO76266.1 - 5.2e-07 29.6 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.21 CDO76266.1 - 0.0001 21.8 0.0 0.00059 19.3 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CDO76266.1 - 0.00012 22.1 0.4 0.0025 17.8 0.4 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CDO76266.1 - 0.00016 22.0 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 CDO76266.1 - 0.0002 21.7 0.2 0.002 18.4 0.1 2.2 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CDO76266.1 - 0.0019 17.9 0.0 0.053 13.2 0.0 2.3 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 CDO76266.1 - 0.0023 18.3 0.0 0.0041 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CDO76266.1 - 0.0024 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 CDO76266.1 - 0.0025 17.9 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 CDO76266.1 - 0.0028 17.4 0.0 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 CDO76266.1 - 0.0031 17.0 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 CDO76266.1 - 0.0061 15.7 0.0 0.0093 15.0 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 CDO76266.1 - 0.0071 16.5 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CDO76266.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CDO76266.1 - 0.021 15.3 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 CDO76266.1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 CDO76266.1 - 0.037 13.8 0.1 0.17 11.7 0.1 1.9 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_14 PF13173.6 CDO76266.1 - 0.044 13.8 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CDO76266.1 - 0.048 13.1 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 CDO76266.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 CDO76266.1 - 0.072 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CDO76266.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 CDO76266.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.13 CDO76266.1 - 0.19 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_29 PF13555.6 CDO76266.1 - 0.25 11.1 2.6 0.29 10.9 0.0 2.3 3 0 0 3 3 2 0 P-loop containing region of AAA domain Ran_BP1 PF00638.18 CDO76267.1 - 1.1e-50 171.0 0.6 2.8e-50 169.7 0.6 1.6 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CDO76267.1 - 4.3e-05 23.4 0.8 0.00031 20.6 0.8 2.0 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.14 CDO76267.1 - 0.00049 19.8 0.7 0.00065 19.4 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) EBV-NA3 PF05009.12 CDO76267.1 - 0.39 10.2 5.3 0.56 9.7 5.3 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CT47 PF15623.6 CDO76267.1 - 2.1 8.1 28.0 0.3 10.9 23.8 1.7 2 0 0 2 2 2 0 Cancer/testis gene family 47 RNA_pol_Rpc4 PF05132.14 CDO76267.1 - 2.4 8.6 10.1 3.8 7.9 10.1 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 EMP24_GP25L PF01105.24 CDO76268.1 - 5.2e-50 169.9 0.1 5.8e-50 169.7 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kinesin PF00225.23 CDO76269.1 - 1.9e-107 359.0 0.0 3e-107 358.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDO76269.1 - 6.3e-25 87.8 0.0 1.1e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding JAKMIP_CC3 PF16034.5 CDO76269.1 - 0.17 11.8 8.3 0.31 11.0 7.0 2.1 1 1 0 1 1 1 0 JAKMIP CC3 domain Amidohydro_2 PF04909.14 CDO76270.1 - 3.8e-07 30.2 0.1 5.2e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 CDO76270.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family LON_substr_bdg PF02190.16 CDO76271.1 - 1.2e-20 74.3 0.0 1e-19 71.3 0.0 2.1 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 CDO76271.1 - 6.5e-12 45.1 20.7 3e-10 39.8 11.9 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO76271.1 - 1.5e-09 37.7 18.9 5.5e-07 29.5 7.3 2.8 2 1 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CDO76271.1 - 1.9e-09 37.5 21.0 0.00011 22.3 10.4 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CDO76271.1 - 2.8e-09 36.8 16.3 4e-06 26.7 10.0 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 CDO76271.1 - 2.4e-08 33.7 19.5 2.3e-07 30.5 10.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDO76271.1 - 9.6e-08 31.8 13.7 1.8e-07 30.9 5.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CDO76271.1 - 2.5e-06 27.7 22.3 8.7e-06 26.0 11.8 2.7 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 CDO76271.1 - 5e-06 26.3 6.7 5e-06 26.3 6.7 3.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CDO76271.1 - 0.0034 17.5 5.6 0.0034 17.5 5.6 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 CDO76271.1 - 0.0084 16.0 6.4 0.16 11.9 2.4 2.8 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CDO76271.1 - 0.011 16.0 7.7 0.011 16.0 7.7 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CDO76271.1 - 0.03 14.1 5.4 0.042 13.7 3.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Apt1 PF10351.9 CDO76271.1 - 0.97 8.2 2.9 1.6 7.5 2.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain F-box-like PF12937.7 CDO76272.1 - 1.6e-05 24.7 0.7 1.6e-05 24.7 0.7 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDO76272.1 - 0.21 11.5 0.1 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 F-box domain G6PD_C PF02781.16 CDO76273.1 - 2.5e-74 250.1 0.0 2.2e-43 148.5 0.0 2.1 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CDO76273.1 - 3.1e-52 177.8 0.0 9.1e-52 176.2 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain FmiP_Thoc5 PF09766.9 CDO76274.1 - 1.6e-31 109.9 10.8 1.8e-31 109.8 10.8 1.0 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF1204 PF06721.11 CDO76274.1 - 0.014 14.9 3.9 0.017 14.6 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) FAM178 PF14816.6 CDO76274.1 - 0.028 13.4 6.1 0.034 13.1 5.5 1.5 1 1 0 1 1 1 0 Family of unknown function, FAM178 FAM167 PF11652.8 CDO76274.1 - 0.14 12.6 2.9 4.1 8.0 0.6 2.9 2 1 1 3 3 3 0 FAM167 Mod_r PF07200.13 CDO76274.1 - 0.28 11.3 11.6 0.13 12.3 9.2 1.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein UQ_con PF00179.26 CDO76275.1 - 2.1e-34 118.2 0.2 1e-26 93.2 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme MARVEL PF01284.23 CDO76276.1 - 0.5 10.4 8.7 1.1 9.3 8.7 1.6 1 1 0 1 1 1 0 Membrane-associating domain MARVEL PF01284.23 CDO76277.1 - 0.1 12.6 11.5 0.18 11.8 11.2 1.5 1 1 0 1 1 1 0 Membrane-associating domain QSregVF_b PF12843.7 CDO76277.1 - 0.21 11.5 0.0 0.45 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor TcpE PF12648.7 CDO76277.1 - 7.6 7.1 7.3 2.3 8.8 0.1 2.2 2 0 0 2 2 2 0 TcpE family AMP-binding PF00501.28 CDO76278.1 - 1.3e-33 116.3 0.0 4.6e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme ACAS_N PF16177.5 CDO76278.1 - 2.5e-07 30.5 0.9 4.9e-07 29.6 0.9 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CDO76278.1 - 0.0089 17.0 0.1 0.019 15.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 CDO76281.1 - 2e-08 33.9 0.0 1.2e-05 24.8 0.0 3.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76281.1 - 3.5e-05 23.2 0.0 6.8e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO76281.1 - 0.1 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase rve PF00665.26 CDO76282.1 - 2.4e-14 53.5 0.0 4.5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO76282.1 - 2.2e-07 30.7 0.1 4.6e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 CDO76282.1 - 0.14 11.9 0.5 0.58 10.0 0.0 2.2 3 0 0 3 3 3 0 Integrase core domain RP-C_C PF11800.8 CDO76283.1 - 0.22 11.6 15.3 1.4 8.9 5.9 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region CENP-Q PF13094.6 CDO76283.1 - 0.58 10.4 27.1 0.066 13.4 7.3 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.6 CDO76283.1 - 4.2 6.6 13.3 1.9 7.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MCU PF04678.13 CDO76283.1 - 4.3 7.4 9.1 8.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF2390 PF09523.10 CDO76284.1 - 3.4 8.0 12.5 10 6.5 6.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) rve PF00665.26 CDO76285.1 - 9e-14 51.7 0.0 1.9e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO76285.1 - 6.2e-07 29.2 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ferrochelatase PF00762.19 CDO76285.1 - 0.035 13.2 0.5 3.6 6.6 0.1 2.3 1 1 1 2 2 2 0 Ferrochelatase SAICAR_synt PF01259.18 CDO76286.1 - 5.3e-101 337.5 0.0 6.4e-101 337.2 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase PABP PF00658.18 CDO76286.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain MFS_1 PF07690.16 CDO76287.1 - 3.2e-28 98.7 35.3 3.2e-28 98.7 35.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Dimer_Tnp_hAT PF05699.14 CDO76288.1 - 8.5e-13 47.9 2.4 2.4e-12 46.5 0.2 2.8 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region DUF4820 PF16091.5 CDO76288.1 - 0.018 14.4 0.5 0.032 13.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF737 PF05300.11 CDO76288.1 - 0.63 10.4 5.2 0.89 9.9 3.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Kinesin_assoc PF16183.5 CDO76288.1 - 3.2 7.9 4.8 3.7 7.7 0.0 3.2 3 1 0 3 3 3 0 Kinesin-associated DNA_pol_B PF00136.21 CDO76289.1 - 2.7e-118 395.6 0.0 3.7e-118 395.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CDO76289.1 - 9.9e-61 204.7 2.2 1.7e-60 204.0 2.2 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 CDO76289.1 - 7.3e-28 97.7 0.0 1.1e-26 93.8 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 CDO76289.1 - 5.2e-21 74.5 5.8 2e-20 72.7 5.8 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 CDO76289.1 - 0.035 13.0 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Glutaredoxin PF00462.24 CDO76290.1 - 6.3e-18 64.8 0.0 1.3e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin DDE_3 PF13358.6 CDO76291.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease AICARFT_IMPCHas PF01808.18 CDO76292.1 - 7.7e-77 258.6 0.1 1.1e-76 258.2 0.1 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CDO76292.1 - 1.3e-24 86.2 0.0 2.4e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain FAD_binding_3 PF01494.19 CDO76293.1 - 8.2e-21 74.6 0.1 1.8e-20 73.5 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CDO76293.1 - 3.4e-09 36.4 0.3 0.00014 21.2 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDO76293.1 - 6.4e-08 32.6 2.6 0.00012 21.7 2.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDO76293.1 - 3.1e-06 27.3 2.1 7.1e-06 26.2 2.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CDO76293.1 - 7.3e-06 25.5 0.3 0.075 12.3 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 CDO76293.1 - 1.6e-05 24.0 0.1 0.022 13.6 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 CDO76293.1 - 3.2e-05 22.8 0.2 0.00015 20.6 0.2 1.8 1 1 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 CDO76293.1 - 8.2e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDO76293.1 - 8.9e-05 21.7 1.0 8.9e-05 21.7 1.0 2.0 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 CDO76293.1 - 0.00064 20.2 0.1 0.0067 17.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO76293.1 - 0.0016 17.8 0.1 0.0033 16.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 CDO76293.1 - 0.0031 16.8 0.6 0.16 11.2 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO76293.1 - 0.027 14.4 2.5 2.3 8.2 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 CDO76293.1 - 0.029 13.5 0.1 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CDO76293.1 - 0.035 13.1 0.9 0.24 10.4 0.9 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein RabGAP-TBC PF00566.18 CDO76295.1 - 1.3e-44 152.5 0.0 2.1e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 CDO76295.1 - 3.8e-05 23.3 1.6 0.00083 19.1 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CDO76295.1 - 6.3e-05 23.3 1.5 0.00053 20.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CDO76295.1 - 0.00011 21.5 0.3 0.00067 19.0 0.1 2.4 2 0 0 2 2 2 1 EF hand GRAM PF02893.20 CDO76295.1 - 0.00036 20.4 0.0 0.00098 19.0 0.0 1.7 1 0 0 1 1 1 1 GRAM domain EF-hand_8 PF13833.6 CDO76295.1 - 0.0025 17.6 0.4 0.12 12.2 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CDO76295.1 - 0.059 13.7 0.1 0.2 12.0 0.1 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 CDO76295.1 - 0.083 12.4 0.0 0.29 10.7 0.0 1.9 1 0 0 1 1 1 0 EF hand WD40 PF00400.32 CDO76296.1 - 4e-55 182.5 23.8 3.3e-10 40.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO76296.1 - 4.4e-18 65.4 1.9 0.0025 18.1 0.1 5.3 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDO76296.1 - 7.4e-09 35.8 0.7 0.0039 17.1 0.2 3.8 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CDO76296.1 - 1.8e-07 30.2 8.7 0.012 14.3 0.2 4.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CDO76296.1 - 1.2e-05 24.8 1.1 0.0034 16.8 0.2 2.9 3 1 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 CDO76296.1 - 0.00013 21.1 9.2 0.11 11.4 0.0 4.5 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pectate_lyase22 PF14583.6 CDO76296.1 - 0.0034 16.1 0.2 0.036 12.7 0.0 2.2 1 1 0 2 2 2 1 Oligogalacturonate lyase CAP_N PF01213.19 CDO76296.1 - 0.24 10.9 3.8 0.37 10.2 3.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aldo_ket_red PF00248.21 CDO76297.1 - 1.6e-40 139.1 0.3 3.2e-35 121.8 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family p450 PF00067.22 CDO76298.1 - 1.2e-54 185.8 0.0 2.8e-54 184.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 CDO76299.1 - 6.3e-26 91.5 0.0 8.6e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDO76299.1 - 1.2e-13 50.7 0.0 1.6e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 CDO76299.1 - 0.00063 20.4 3.0 0.00094 19.8 3.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 CDO76299.1 - 0.013 14.4 0.1 0.068 12.0 0.1 1.9 1 1 0 1 1 1 0 Carboxylesterase family Peptidase_S9 PF00326.21 CDO76299.1 - 0.028 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.8 CDO76299.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HD_3 PF13023.6 CDO76300.1 - 6.5e-23 81.5 1.9 7.4e-13 48.8 0.1 2.1 1 1 1 2 2 2 2 HD domain HD PF01966.22 CDO76300.1 - 5.3e-05 23.4 0.3 9.5e-05 22.6 0.3 1.5 1 1 0 1 1 1 1 HD domain HD_2 PF12917.7 CDO76300.1 - 0.00017 21.4 0.8 0.0017 18.1 0.1 2.0 1 1 1 2 2 2 1 HD containing hydrolase-like enzyme RINGv PF12906.7 CDO76301.1 - 1.4e-15 57.2 8.0 2.4e-15 56.4 8.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CDO76301.1 - 0.0086 16.4 9.1 0.014 15.7 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 CDO76301.1 - 0.79 9.9 4.1 1.5 9.1 4.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain SDA1 PF05285.12 CDO76301.1 - 4.4 6.6 13.8 5.9 6.2 0.1 2.2 2 0 0 2 2 2 0 SDA1 PALP PF00291.25 CDO76302.1 - 9.1e-28 97.5 0.0 1.7e-27 96.6 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme DUF3584 PF12128.8 CDO76303.1 - 0.0044 14.6 27.9 0.0073 13.9 27.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) BST2 PF16716.5 CDO76303.1 - 0.022 15.3 5.1 0.022 15.3 5.1 4.9 3 1 2 5 5 5 0 Bone marrow stromal antigen 2 Lebercilin PF15619.6 CDO76303.1 - 0.04 13.6 42.3 0.018 14.7 26.5 3.1 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease NPV_P10 PF05531.12 CDO76303.1 - 0.25 11.8 5.6 11 6.5 3.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 CDO76303.1 - 0.37 11.2 38.1 2.1 8.7 26.4 3.3 2 1 1 3 3 3 0 Fez1 SHE3 PF17078.5 CDO76303.1 - 1.1 8.9 19.4 3.3 7.4 19.4 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 ADIP PF11559.8 CDO76303.1 - 2.3 8.3 43.6 0.72 9.9 14.6 4.8 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 CDO76303.1 - 3.2 7.9 44.6 2.8 8.1 7.0 4.3 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) GAS PF13851.6 CDO76303.1 - 4.2 6.7 39.5 0.2 11.0 4.4 4.1 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 CDO76303.1 - 4.6 7.0 37.8 3.7 7.3 4.4 3.6 2 1 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH ISG65-75 PF11727.8 CDO76303.1 - 4.9 6.3 14.6 5 6.3 5.5 2.3 2 0 0 2 2 2 0 Invariant surface glycoprotein BORCS8 PF10167.9 CDO76303.1 - 5.8 6.9 9.1 7 6.6 0.5 3.6 3 1 1 4 4 4 0 BLOC-1-related complex sub-unit 8 Fib_alpha PF08702.10 CDO76303.1 - 7.1 6.8 22.4 2.6 8.2 4.0 4.1 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 CDO76303.1 - 8.6 6.7 18.1 5.6 7.3 0.1 4.3 2 1 3 5 5 4 0 Bacterial protein of unknown function (DUF948) DUF1515 PF07439.11 CDO76303.1 - 8.6 6.4 19.4 3 7.9 1.8 3.8 1 1 1 4 4 4 0 Protein of unknown function (DUF1515) Spc7 PF08317.11 CDO76303.1 - 9 5.1 38.8 1.2 7.9 18.0 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 CDO76304.1 - 0.59 9.4 9.9 0.85 8.9 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 CDO76304.1 - 0.64 8.5 12.6 0.83 8.1 12.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family LXG PF04740.12 CDO76304.1 - 0.93 9.2 9.0 0.15 11.7 4.4 1.9 2 0 0 2 2 2 0 LXG domain of WXG superfamily TMPIT PF07851.13 CDO76304.1 - 2.1 7.5 5.8 3.8 6.7 5.8 1.5 1 0 0 1 1 1 0 TMPIT-like protein Spot_14 PF07084.12 CDO76304.1 - 2.4 8.3 6.5 3.4 7.8 5.3 1.7 1 1 1 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 Asp PF00026.23 CDO76305.1 - 1.6e-68 231.4 8.2 1.8e-68 231.3 8.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO76305.1 - 2e-06 28.2 1.2 2.2e-05 24.7 1.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CDO76305.1 - 0.044 13.6 0.1 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal FlgN PF05130.12 CDO76306.1 - 0.096 13.2 0.6 0.26 11.8 0.1 1.9 2 1 0 2 2 2 0 FlgN protein rve PF00665.26 CDO76308.1 - 1.3e-06 28.6 0.0 5.2e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CDO76308.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 DDE domain RT_RNaseH_2 PF17919.1 CDO76309.1 - 3.1e-12 46.4 0.0 5.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO76309.1 - 2.7e-10 40.5 0.0 4.9e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDO76309.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain FlgN PF05130.12 CDO76310.1 - 0.17 12.4 1.8 0.52 10.8 0.2 2.1 2 1 0 2 2 2 0 FlgN protein CorA PF01544.18 CDO76313.1 - 0.17 11.2 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein NLE PF08154.12 CDO76314.1 - 2.9e-15 56.5 0.1 6.9e-15 55.3 0.0 1.6 2 0 0 2 2 2 1 NLE (NUC135) domain WD40 PF00400.32 CDO76314.1 - 7.6e-05 23.4 7.7 8.9 7.4 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 CDO76314.1 - 0.029 13.0 1.0 0.29 9.7 0.0 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 EELM2 PF15863.5 CDO76315.1 - 0.11 12.7 0.1 0.69 10.0 0.0 1.9 2 0 0 2 2 2 0 Extended EGL-27 and MTA1 homology domain Lipase_GDSL PF00657.22 CDO76317.1 - 5.9e-08 32.9 0.0 1.3e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CDO76317.1 - 7.6e-07 29.7 3.8 2.3e-06 28.1 3.8 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DDE_1 PF03184.19 CDO76318.1 - 6.5e-16 58.5 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CDO76318.1 - 2.5e-09 37.0 0.0 8.3e-09 35.4 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 CDO76318.1 - 0.0012 18.6 0.9 0.01 15.6 0.1 2.7 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_psq PF05225.16 CDO76318.1 - 0.0042 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain RasGAP_C PF03836.15 CDO76318.1 - 0.37 10.9 5.9 1.2 9.3 5.9 1.8 1 1 0 1 1 1 0 RasGAP C-terminus Pkinase_fungal PF17667.1 CDO76320.1 - 2.1e-39 135.5 0.0 3.3e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CDO76320.1 - 0.00033 20.1 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CDO76320.1 - 0.0019 18.1 0.0 0.01 15.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO76321.1 - 7.9e-38 130.3 3.3 2.8e-18 65.9 0.0 2.4 3 0 0 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 CDO76321.1 - 0.051 12.9 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF348 PF03990.14 CDO76322.1 - 0.24 11.2 0.9 1.6 8.5 0.0 2.6 2 1 0 2 2 2 0 G5-linked-Ubiquitin-like domain Mpv17_PMP22 PF04117.12 CDO76323.1 - 1e-20 73.7 0.3 1.6e-20 73.1 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF4241 PF14025.6 CDO76324.1 - 0.0028 18.0 0.8 0.13 12.5 0.6 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4241) Phage_ABA_S PF18066.1 CDO76325.1 - 0.022 15.4 0.0 0.49 11.1 0.0 2.5 2 0 0 2 2 2 0 Phage ABA sandwich domain Cys_rich_VLP PF14194.6 CDO76325.1 - 0.2 11.8 0.1 0.38 10.9 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich VLP PLA2_B PF01735.18 CDO76326.1 - 7e-75 252.3 0.0 1.5e-36 125.9 0.0 2.1 1 1 1 2 2 2 2 Lysophospholipase catalytic domain Glyco_hydro_28 PF00295.17 CDO76327.1 - 3.3e-29 102.0 3.1 4.2e-29 101.6 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 CDO76327.1 - 0.00018 21.5 11.4 0.002 18.0 3.1 3.3 1 1 1 2 2 2 2 Pectate lyase superfamily protein Presenilin PF01080.17 CDO76328.1 - 0.66 8.7 7.4 0.71 8.6 7.4 1.3 1 0 0 1 1 1 0 Presenilin U79_P34 PF03064.16 CDO76328.1 - 0.68 9.3 13.1 0.029 13.7 5.8 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DNA_pol_phi PF04931.13 CDO76328.1 - 2 6.4 7.7 3.3 5.7 7.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi SAPS PF04499.15 CDO76328.1 - 9.2 4.9 6.8 14 4.3 6.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Integrase_H2C2 PF17921.1 CDO76329.1 - 2.2e-15 56.5 0.3 5.2e-15 55.3 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO76329.1 - 1.7e-14 54.0 0.0 3.7e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDO76329.1 - 8.2e-08 32.3 0.1 1.5e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 CDO76329.1 - 3e-07 30.3 0.0 5.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ferrochelatase PF00762.19 CDO76329.1 - 0.088 11.9 0.3 4.8 6.2 0.0 2.2 1 1 1 2 2 2 0 Ferrochelatase Velvet PF11754.8 CDO76331.1 - 9.7e-47 160.0 0.5 1e-38 133.8 0.0 4.0 2 2 1 3 3 3 2 Velvet factor DNA_pol_B_thumb PF14791.6 CDO76332.1 - 1.3e-20 73.3 0.0 8.7e-20 70.7 0.0 2.5 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 CDO76332.1 - 2.7e-20 71.9 0.2 7.5e-19 67.3 0.0 2.7 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 CDO76332.1 - 2.2e-18 66.5 0.6 1.7e-16 60.5 0.0 2.9 3 0 0 3 3 3 1 DNA polymerase beta palm HHH_8 PF14716.6 CDO76332.1 - 2e-14 53.7 0.3 4.4e-14 52.6 0.3 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 CDO76332.1 - 0.0017 18.9 0.4 1.4 9.6 0.2 2.9 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_2 PF12826.7 CDO76332.1 - 0.037 14.1 0.1 0.86 9.7 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif BRCT PF00533.26 CDO76332.1 - 0.077 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain HHH PF00633.23 CDO76332.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif LIG3_BRCT PF16759.5 CDO76332.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Methyltransf_23 PF13489.6 CDO76333.1 - 2.4e-11 43.7 0.0 3.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO76333.1 - 3.5e-10 40.5 0.0 8.4e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO76333.1 - 2.9e-09 36.9 0.0 1e-08 35.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO76333.1 - 9.3e-09 35.8 0.0 1.6e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO76333.1 - 2.5e-06 28.2 0.0 8.1e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CDO76333.1 - 0.00011 21.8 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_8 PF05148.15 CDO76333.1 - 0.0013 18.6 0.0 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 Hypothetical methyltransferase FtsJ PF01728.19 CDO76333.1 - 0.0068 16.5 0.0 0.016 15.3 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 CDO76333.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 CDO76333.1 - 0.0079 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_2 PF00891.18 CDO76333.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 CDO76333.1 - 0.036 13.4 0.0 0.22 10.8 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Peptidase_M16 PF00675.20 CDO76334.1 - 4.5e-21 75.4 0.1 7.8e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CDO76334.1 - 2.9e-07 30.7 0.0 5e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Peptidase M16 inactive domain DUF659 PF04937.15 CDO76337.1 - 0.0034 17.3 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) HflK_N PF12221.8 CDO76340.1 - 0.52 10.4 2.4 1.7 8.8 0.7 2.8 2 0 0 2 2 2 0 Bacterial membrane protein N terminal RFC1 PF08519.12 CDO76341.1 - 8.2e-57 191.8 0.0 1.2e-55 188.0 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 CDO76341.1 - 3e-13 50.0 0.0 1.1e-12 48.2 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 CDO76341.1 - 2.4e-10 40.9 0.0 7.4e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CDO76341.1 - 5.1e-05 23.3 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 CDO76341.1 - 0.0011 18.7 1.2 0.0027 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CDO76341.1 - 0.0076 16.6 0.0 0.035 14.4 0.0 2.1 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 CDO76341.1 - 0.012 16.0 0.8 0.03 14.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 CDO76341.1 - 0.021 14.6 0.0 0.079 12.7 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 CDO76341.1 - 0.026 14.3 1.9 0.032 14.0 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_5 PF07728.14 CDO76341.1 - 0.027 14.5 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CDO76341.1 - 0.029 14.4 0.0 0.089 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDO76341.1 - 0.06 13.6 0.1 0.26 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CDO76341.1 - 0.061 13.7 0.2 0.57 10.6 0.0 2.7 2 1 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 CDO76341.1 - 0.069 13.1 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 CDO76341.1 - 0.13 12.4 0.6 0.66 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain HemY_N PF07219.13 CDO76341.1 - 1.2 9.3 3.3 3.1 8.0 3.3 1.6 1 0 0 1 1 1 0 HemY protein N-terminus Asp PF00026.23 CDO76342.1 - 3e-78 263.4 0.4 3.5e-78 263.2 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO76342.1 - 5.8e-12 46.2 0.7 0.00017 21.9 1.2 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO76342.1 - 4.5e-05 24.0 0.4 0.013 16.2 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 CDO76342.1 - 0.096 12.5 0.2 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DUF1129 PF06570.11 CDO76343.1 - 0.46 9.9 2.4 0.9 9.0 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) FA_desaturase PF00487.24 CDO76343.1 - 1.3 8.8 8.2 1.6 8.5 7.1 1.7 1 1 0 1 1 1 0 Fatty acid desaturase GMC_oxred_N PF00732.19 CDO76344.1 - 1.2e-61 208.7 0.0 1.8e-61 208.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO76344.1 - 3.4e-33 115.2 0.0 7e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CDO76344.1 - 1.7e-06 27.4 0.1 2.6e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 CDO76344.1 - 0.00054 19.3 0.2 0.0023 17.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 CDO76344.1 - 0.0014 17.8 0.5 0.0072 15.4 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CDO76344.1 - 0.014 14.6 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDO76344.1 - 0.053 12.2 0.4 0.086 11.5 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 CDO76344.1 - 0.19 10.8 0.1 0.64 9.0 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.16 CDO76345.1 - 8.3e-19 67.7 39.9 1.8e-15 56.7 9.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO76345.1 - 2.1e-08 33.5 1.4 2.1e-08 33.5 1.4 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CDO76345.1 - 0.00025 19.6 1.8 0.00025 19.6 1.8 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LIDHydrolase PF10230.9 CDO76345.1 - 0.19 11.2 0.6 0.49 9.9 0.1 2.0 2 1 1 3 3 3 0 Lipid-droplet associated hydrolase Endomucin PF07010.12 CDO76346.1 - 0.045 13.7 2.4 0.15 12.1 2.4 1.9 1 0 0 1 1 1 0 Endomucin Glyco_hydro_85 PF03644.13 CDO76347.1 - 1.7e-85 287.1 0.0 3e-85 286.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Suf PF05843.14 CDO76347.1 - 8.9e-79 265.5 7.6 2.3e-78 264.2 0.0 4.1 3 1 2 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CDO76347.1 - 3.1e-10 40.0 6.6 0.047 14.5 0.0 7.1 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDO76347.1 - 4.9e-09 36.6 0.4 0.0087 16.5 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat FTCD_C PF04961.12 CDO76347.1 - 0.0019 18.0 0.3 0.007 16.2 0.0 1.9 2 0 0 2 2 2 1 Formiminotransferase-cyclodeaminase TPR_16 PF13432.6 CDO76347.1 - 0.005 17.4 1.5 14 6.5 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 CDO76347.1 - 0.0082 15.4 0.8 0.14 11.4 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDO76347.1 - 0.13 12.6 0.1 66 4.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDO76347.1 - 0.14 12.8 0.0 1e+02 3.8 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.10 CDO76347.1 - 0.17 10.9 10.7 0.38 9.8 0.5 4.0 3 1 0 3 3 3 0 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 CDO76347.1 - 0.38 11.0 4.1 8.5 6.8 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 CDO76348.1 - 3.1e-49 166.8 0.0 1.1e-41 142.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CDO76348.1 - 4e-10 39.3 0.0 1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CDO76348.1 - 1.8e-06 28.5 5.7 5e-05 23.8 0.2 4.1 3 2 1 4 4 3 1 AAA ATPase domain IstB_IS21 PF01695.17 CDO76348.1 - 4.2e-06 26.6 0.0 0.0001 22.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 CDO76348.1 - 3.6e-05 24.0 0.0 9.4e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDO76348.1 - 0.00063 20.0 1.4 0.22 11.8 0.0 4.3 4 1 0 5 5 5 1 AAA domain AAA_5 PF07728.14 CDO76348.1 - 0.0023 17.9 0.1 0.021 14.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CDO76348.1 - 0.01 15.5 0.0 0.32 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CDO76348.1 - 0.011 15.9 3.0 0.039 14.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain RuvB_N PF05496.12 CDO76348.1 - 0.042 13.6 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CDO76348.1 - 0.062 13.8 0.0 0.062 13.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 CDO76348.1 - 0.063 12.7 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CDO76348.1 - 0.065 13.5 1.0 0.13 12.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 CDO76348.1 - 0.07 12.6 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 CDO76348.1 - 0.077 12.4 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 CDO76348.1 - 0.091 12.5 0.0 1.7 8.4 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain TIP49 PF06068.13 CDO76348.1 - 0.097 11.9 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 CDO76348.1 - 0.098 12.8 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CDO76348.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 CDO76348.1 - 0.19 11.5 3.3 0.86 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain SPESP1 PF15754.5 CDO76348.1 - 8.6 5.4 8.7 0.22 10.7 1.9 1.8 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 RRM_1 PF00076.22 CDO76349.1 - 1.4e-33 114.5 0.1 1.7e-15 56.6 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDO76349.1 - 6.5e-12 45.4 0.1 2.1e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CDO76349.1 - 0.0077 16.2 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 CDO76349.1 - 0.11 12.4 0.0 12 5.9 0.0 2.2 2 0 0 2 2 2 0 RL domain SNO PF01174.19 CDO76350.1 - 5.9e-29 101.2 0.0 9.8e-17 61.4 0.0 3.0 2 1 1 3 3 3 3 SNO glutamine amidotransferase family BUD22 PF09073.10 CDO76352.1 - 0.082 12.2 11.0 0.048 13.0 8.5 1.9 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 CDO76352.1 - 0.12 10.7 2.4 0.14 10.4 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CDO76352.1 - 0.15 10.3 6.8 0.19 9.9 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family FAM220 PF15487.6 CDO76352.1 - 1.3 8.5 3.8 2.2 7.9 3.8 1.3 1 0 0 1 1 1 0 FAM220 family FAM176 PF14851.6 CDO76352.1 - 7.5 6.2 6.6 8.5 6.0 4.0 2.4 2 1 0 2 2 2 0 FAM176 family Peptidase_S10 PF00450.22 CDO76353.1 - 2.6e-70 237.9 1.2 7.3e-51 173.9 3.9 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase Peptidase_S10 PF00450.22 CDO76356.1 - 4.9e-66 223.9 0.0 7e-65 220.1 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 CDO76357.1 - 7.5e-46 157.4 0.2 3.2e-29 102.6 0.0 2.9 1 1 1 2 2 2 2 Serine carboxypeptidase FYDLN_acid PF09538.10 CDO76358.1 - 0.0019 18.9 14.7 0.0047 17.6 14.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) IBR PF01485.21 CDO76358.1 - 0.0041 17.3 0.3 0.0078 16.4 0.3 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain Vfa1 PF08432.10 CDO76358.1 - 0.18 12.1 15.9 0.31 11.4 15.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 CDO76358.1 - 0.34 10.7 13.1 0.51 10.1 13.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 CDO76358.1 - 0.41 9.4 4.5 0.51 9.1 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDRGK PF09756.9 CDO76358.1 - 0.8 9.3 22.0 1.2 8.7 22.0 1.2 1 0 0 1 1 1 0 DDRGK domain NOA36 PF06524.12 CDO76358.1 - 0.86 8.9 12.4 1.3 8.3 12.4 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-T_N PF16171.5 CDO76358.1 - 0.89 8.4 13.7 1.5 7.7 13.7 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus Spore_coat_CotO PF14153.6 CDO76358.1 - 1.3 9.0 19.7 2 8.3 19.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.17 CDO76358.1 - 1.8 8.6 5.2 3.3 7.8 5.2 1.4 1 0 0 1 1 1 0 DDHD domain DUF4554 PF15091.6 CDO76358.1 - 2.1 7.2 8.1 3.4 6.5 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Pox_Ag35 PF03286.14 CDO76358.1 - 2.4 7.9 20.9 0.17 11.7 15.7 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.8 CDO76358.1 - 3 8.0 21.2 5.4 7.2 21.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NPR3 PF03666.13 CDO76358.1 - 3.5 6.3 15.0 5 5.8 15.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 CDO76358.1 - 3.5 6.5 9.6 4.8 6.0 9.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Trypan_PARP PF05887.11 CDO76358.1 - 4.1 7.4 22.1 0.033 14.2 11.2 2.5 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) Band_3_cyto PF07565.13 CDO76358.1 - 4.4 7.0 11.2 7 6.4 11.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Plasmodium_Vir PF05795.11 CDO76358.1 - 4.9 6.5 8.8 7.4 5.9 8.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.16 CDO76358.1 - 6.3 6.8 4.8 7.4 6.6 3.6 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CDO76358.1 - 6.9 5.3 13.9 10 4.8 13.9 1.1 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 CDO76358.1 - 8.5 5.1 10.1 12 4.6 10.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF4687 PF15747.5 CDO76358.1 - 9.2 6.8 10.9 1.3 9.6 3.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4687) adh_short PF00106.25 CDO76360.1 - 7.9e-26 90.7 0.1 1.3e-20 73.7 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO76360.1 - 1.7e-11 44.1 0.0 1.5e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO76360.1 - 6.4e-07 29.5 0.1 1.1e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO76360.1 - 0.019 14.5 0.1 0.026 14.0 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HATPase_c PF02518.26 CDO76360.1 - 0.18 12.3 0.0 0.33 11.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.25 CDO76361.1 - 7.2e-29 100.6 0.0 5.7e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO76361.1 - 1.4e-15 57.6 0.0 2.2e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO76361.1 - 1.9e-07 31.2 0.1 3e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO76361.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDO76361.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1918 PF08940.11 CDO76361.1 - 0.11 12.1 0.0 0.4 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) adh_short PF00106.25 CDO76362.1 - 1.1e-10 41.3 0.0 4.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO76362.1 - 3.9e-05 23.3 0.0 0.00025 20.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO76362.1 - 0.024 14.6 0.0 0.048 13.6 0.0 1.5 2 0 0 2 2 2 0 KR domain BclA_C PF18573.1 CDO76363.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 BclA C-terminal domain MFS_1 PF07690.16 CDO76364.1 - 1.1e-19 70.6 17.8 6.7e-18 64.7 5.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CDO76364.1 - 4.1e-07 29.7 0.1 1.1e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Nodulin-like Tat PF00539.18 CDO76364.1 - 0.12 12.5 0.6 0.28 11.3 0.6 1.5 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) FGE-sulfatase PF03781.16 CDO76366.1 - 9e-20 71.3 1.2 1.4e-17 64.1 1.2 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 CDO76366.1 - 6.5e-08 33.1 1.0 1.5e-07 32.0 1.0 1.7 1 0 0 1 1 1 1 DinB superfamily Tcf25 PF04910.14 CDO76367.1 - 1.5e-95 320.3 0.0 2.3e-95 319.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF2681 PF10883.8 CDO76367.1 - 0.38 11.2 1.7 3.7 8.0 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TFB6 PF17110.5 CDO76367.1 - 2.3 8.0 6.2 1.3 8.7 1.1 2.2 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH PTPRCAP PF15713.5 CDO76367.1 - 9.9 6.4 13.7 4.4 7.6 3.8 2.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated AIRC PF00731.20 CDO76368.1 - 4.6e-63 211.2 1.0 1.2e-62 209.9 1.0 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 CDO76368.1 - 6e-59 198.5 0.0 8.9e-59 197.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 CDO76368.1 - 7.1e-19 67.2 0.0 1.3e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 CDO76368.1 - 5.5e-05 22.8 0.0 9.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 CDO76368.1 - 0.0013 18.3 0.0 0.0092 15.5 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CDO76368.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain PrpR_N PF06506.11 CDO76368.1 - 0.18 11.4 0.5 0.58 9.7 0.1 2.1 2 0 0 2 2 2 0 Propionate catabolism activator Rsa3 PF14615.6 CDO76369.1 - 1.7e-15 56.3 0.0 2.4e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 TFIIF_alpha PF05793.12 CDO76369.1 - 0.018 13.7 12.7 0.022 13.4 12.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IMUP PF15761.5 CDO76369.1 - 0.76 10.5 31.7 0.47 11.2 10.4 2.5 1 1 1 2 2 2 0 Immortalisation up-regulated protein SPX PF03105.19 CDO76369.1 - 0.99 9.2 16.4 1.2 9.0 16.4 1.1 1 0 0 1 1 1 0 SPX domain NPR3 PF03666.13 CDO76369.1 - 1.1 8.0 5.3 1.1 7.9 5.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 CDO76369.1 - 1.7 7.4 9.7 2 7.2 9.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Adeno_terminal PF02459.15 CDO76369.1 - 3.6 5.9 4.7 2.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Adenoviral DNA terminal protein Presenilin PF01080.17 CDO76369.1 - 4 6.1 7.3 4.5 5.9 7.3 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 CDO76369.1 - 4.3 5.8 6.7 5.4 5.5 6.7 1.1 1 0 0 1 1 1 0 Macoilin family Npa1 PF11707.8 CDO76370.1 - 8.3e-103 344.3 5.5 4.2e-102 342.0 0.1 3.6 4 0 0 4 4 4 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CDO76370.1 - 1.9e-52 177.8 2.6 3.8e-52 176.8 0.5 2.8 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 CDO76370.1 - 0.001 19.7 0.0 0.0051 17.5 0.0 2.2 1 0 0 1 1 1 1 Creb binding FANCI_S2 PF14676.6 CDO76370.1 - 0.011 16.1 0.3 3.3 8.0 0.0 4.0 3 0 0 3 3 3 0 FANCI solenoid 2 DUF3188 PF11384.8 CDO76370.1 - 0.062 13.0 0.0 0.24 11.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) TPR_19 PF14559.6 CDO76370.1 - 1 9.9 3.7 5.4 7.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Copper-bind PF00127.20 CDO76371.1 - 0.016 15.6 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family p450 PF00067.22 CDO76372.1 - 2.5e-57 194.7 0.0 5e-56 190.4 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 Pkinase_fungal PF17667.1 CDO76373.1 - 2.5e-49 168.2 0.0 1.1e-34 120.0 0.0 2.5 2 1 0 2 2 2 2 Fungal protein kinase HD PF01966.22 CDO76374.1 - 3.6e-11 43.4 0.7 1.1e-10 41.8 0.0 2.2 3 0 0 3 3 3 1 HD domain PDEase_I PF00233.19 CDO76374.1 - 0.016 14.9 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase HD_2 PF12917.7 CDO76374.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Exo_endo_phos PF03372.23 CDO76375.1 - 1.9e-08 34.2 0.2 5.1e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Cellulase PF00150.18 CDO76379.1 - 2e-06 27.4 0.1 2.9e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) UPRTase PF14681.6 CDO76380.1 - 2.3e-59 200.3 0.0 3.3e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase EMG1 PF03587.14 CDO76380.1 - 1.3e-47 161.9 0.0 7.2e-34 117.1 0.0 2.2 2 0 0 2 2 2 2 EMG1/NEP1 methyltransferase Pribosyltran PF00156.27 CDO76380.1 - 0.03 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain CRAL_TRIO PF00650.20 CDO76381.1 - 7.8e-30 103.7 0.0 3.4e-29 101.6 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDO76381.1 - 4.2e-10 39.6 0.3 1.2e-09 38.2 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RNase_T PF00929.24 CDO76386.1 - 3.5e-12 47.2 0.0 6.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Peptidase_S10 PF00450.22 CDO76389.1 - 2.3e-58 198.6 0.2 2.9e-58 198.2 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 CDO76390.1 - 2e-87 294.3 0.0 4.8e-87 293.1 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase OapA_N PF08525.11 CDO76391.1 - 0.91 9.5 4.4 1.1 9.3 0.0 2.4 2 1 0 2 2 2 0 Opacity-associated protein A N-terminal motif MULE PF10551.9 CDO76392.1 - 5.4e-10 39.6 0.0 3.1e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 MULE transposase domain Chromo PF00385.24 CDO76393.1 - 2.5e-07 30.5 0.0 4.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4746 PF15928.5 CDO76393.1 - 0.019 14.4 0.8 0.022 14.2 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) U79_P34 PF03064.16 CDO76393.1 - 0.32 10.3 10.2 0.45 9.8 10.2 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Vfa1 PF08432.10 CDO76393.1 - 2.3 8.5 13.1 3.2 8.0 13.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ATP11 PF06644.11 CDO76393.1 - 8.4 6.1 10.4 3.2 7.5 8.1 1.4 2 0 0 2 2 2 0 ATP11 protein SPT_ssu-like PF11779.8 CDO76395.1 - 4.6e-18 64.6 5.1 7.3e-18 63.9 5.1 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like FOXP-CC PF16159.5 CDO76398.1 - 0.0078 16.8 1.4 0.0078 16.8 1.4 1.9 3 0 0 3 3 3 1 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CDO76398.1 - 4.4 8.4 13.1 2.5 9.2 0.8 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger UBA_4 PF14555.6 CDO76399.1 - 8.9e-08 31.8 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 CDO76399.1 - 2e-07 31.1 0.0 5.1e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 UBX domain Polyoma_coat2 PF00761.20 CDO76399.1 - 0.54 9.9 1.7 0.87 9.2 1.7 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein DUF1682 PF07946.14 CDO76399.1 - 0.9 8.7 11.9 1.3 8.1 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 CDO76399.1 - 3.3 6.4 3.8 4.5 5.9 3.8 1.1 1 0 0 1 1 1 0 Presenilin CUE PF02845.16 CDO76400.1 - 5.8e-11 41.9 0.0 8.8e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain PAX PF00292.18 CDO76400.1 - 0.15 12.0 0.1 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 'Paired box' domain ODV-E18 PF10717.9 CDO76400.1 - 0.27 11.1 0.1 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Hydrolase_4 PF12146.8 CDO76402.1 - 3.5e-14 52.7 0.0 5.5e-11 42.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDO76402.1 - 9e-12 45.2 0.3 2.8e-10 40.3 0.1 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO76402.1 - 3.3e-07 31.1 0.1 4.8e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 CDO76402.1 - 6e-06 26.3 0.0 0.0019 18.2 0.0 2.4 3 0 0 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 CDO76402.1 - 0.00068 18.4 0.2 0.24 10.0 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 CDO76402.1 - 0.0012 18.5 0.0 0.078 12.5 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 CDO76402.1 - 0.0051 16.3 0.0 0.046 13.2 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CDO76402.1 - 0.0057 16.5 0.0 0.4 10.4 0.0 2.8 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 CDO76402.1 - 0.099 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain LIDHydrolase PF10230.9 CDO76402.1 - 0.12 11.9 0.0 0.78 9.2 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 CDO76402.1 - 0.17 11.5 0.0 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.18 CDO76402.1 - 0.17 11.4 0.0 0.99 8.9 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Pkinase PF00069.25 CDO76403.1 - 2.5e-50 171.3 0.0 4.4e-50 170.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76403.1 - 8.4e-26 90.8 0.0 3.9e-18 65.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO76403.1 - 0.0005 19.0 0.0 0.0007 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CDO76403.1 - 0.0015 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO76403.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CDO76403.1 - 0.032 13.6 0.1 8.3 5.6 0.0 3.1 3 0 0 3 3 3 0 Kinase-like FTA2 PF13095.6 CDO76403.1 - 0.039 13.6 0.0 6.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 CDO76403.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Prenylcys_lyase PF07156.14 CDO76404.1 - 1e-67 228.8 0.0 1.4e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 CDO76404.1 - 2.7e-09 37.1 0.0 5.6e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CDO76404.1 - 1.2e-06 28.1 0.0 3.6e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 CDO76404.1 - 7.5e-05 22.5 0.4 0.0011 18.7 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CDO76404.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CDO76404.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDO76404.1 - 0.47 9.5 1.1 0.68 8.9 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4598 PF15370.6 CDO76405.1 - 5.8e-16 58.9 11.7 9.8e-16 58.2 8.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) YL1 PF05764.13 CDO76405.1 - 0.45 10.6 8.2 0.15 12.1 4.3 1.9 2 0 0 2 2 2 0 YL1 nuclear protein CCDC106 PF15794.5 CDO76405.1 - 0.62 9.7 6.9 1.1 9.0 6.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 CDO76405.1 - 1.1 7.4 5.7 1.6 7.0 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 CDO76405.1 - 3.3 6.1 5.9 4.8 5.6 5.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 CDO76405.1 - 5.4 7.0 11.9 9.4 6.2 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Prenylcys_lyase PF07156.14 CDO76406.1 - 1.4e-69 234.9 0.0 1.8e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 CDO76406.1 - 6.3e-11 42.3 0.1 1.3e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CDO76406.1 - 3.5e-10 39.8 0.0 1.7e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 CDO76406.1 - 3.9e-05 23.4 1.5 0.00065 19.4 1.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CDO76406.1 - 0.011 15.8 0.1 0.036 14.1 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CDO76406.1 - 0.014 14.6 0.1 0.039 13.2 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDO76406.1 - 0.15 10.7 0.2 0.23 10.1 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 CDO76406.1 - 0.19 10.8 1.4 0.27 10.3 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pro-kuma_activ PF09286.11 CDO76407.1 - 1.1e-39 136.0 0.0 2.7e-39 134.7 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO76407.1 - 6.4e-10 38.8 0.2 1e-09 38.1 0.2 1.2 1 0 0 1 1 1 1 Subtilase family Ferric_reduct PF01794.19 CDO76408.1 - 1.7e-16 60.4 9.4 3.7e-16 59.4 9.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CDO76408.1 - 1.2e-11 44.6 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CDO76408.1 - 1.3e-08 35.2 0.0 3.6e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Fumarate_red_C PF02300.17 CDO76408.1 - 0.16 12.1 6.4 0.35 10.9 2.6 2.5 2 0 0 2 2 2 0 Fumarate reductase subunit C Glyco_hydro_cc PF11790.8 CDO76409.1 - 1.4e-58 198.3 2.2 1.8e-58 198.0 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Cellulase PF00150.18 CDO76409.1 - 0.044 13.2 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) EF-hand_7 PF13499.6 CDO76410.1 - 3e-11 43.6 0.0 1.6e-06 28.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDO76410.1 - 4e-11 41.9 0.1 0.00017 21.3 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CDO76410.1 - 1.4e-09 36.8 0.1 0.00043 19.6 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 CDO76410.1 - 5.7e-06 26.6 0.0 0.02 15.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CDO76410.1 - 0.00013 21.8 0.0 0.00061 19.6 0.0 2.2 3 0 0 3 3 3 1 EF-hand domain pair SapB_1 PF05184.15 CDO76410.1 - 0.24 11.5 0.0 3.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 EF-hand_5 PF13202.6 CDO76410.1 - 0.25 10.9 1.9 0.87 9.2 0.2 2.5 2 1 0 2 2 2 0 EF hand YrhK PF14145.6 CDO76411.1 - 0.015 15.1 18.7 0.4 10.6 0.0 4.3 3 1 1 4 4 4 0 YrhK-like protein Glyco_hydro_61 PF03443.14 CDO76412.1 - 1.1e-54 185.6 0.0 2e-54 184.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Zn_clus PF00172.18 CDO76413.1 - 3.7e-05 23.8 1.2 5.7e-05 23.2 1.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 CDO76414.1 - 4.9e-57 193.7 0.0 3.6e-42 144.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Isochorismatase PF00857.20 CDO76415.1 - 2.6e-16 60.3 0.0 4.7e-16 59.4 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family Ras PF00071.22 CDO76416.1 - 2.5e-26 92.2 0.0 3.2e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO76416.1 - 2.7e-08 34.0 0.0 4.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 CDO76417.1 - 1.1e-51 171.6 15.1 3.3e-08 34.1 0.0 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO76417.1 - 8.7e-22 77.2 0.0 0.0001 22.5 0.0 8.1 1 1 7 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO76417.1 - 5.2e-16 58.5 2.7 0.0073 15.3 0.0 6.9 1 1 6 7 7 7 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CDO76417.1 - 3.1e-09 36.5 7.7 3.9 7.5 0.0 8.0 8 0 0 8 8 8 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 CDO76417.1 - 4.1e-07 30.1 0.0 0.00055 19.9 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 CDO76417.1 - 0.00032 19.2 0.0 0.4 8.9 0.0 2.7 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 CDO76417.1 - 0.017 14.8 12.2 0.41 10.4 0.1 5.8 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Nbas_N PF15492.6 CDO76417.1 - 0.025 13.9 0.2 25 4.1 0.0 3.9 3 1 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal AIMP2_LysRS_bd PF16780.5 CDO76417.1 - 0.067 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain DUF4372 PF14294.6 CDO76418.1 - 0.18 11.9 0.0 21 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) Zn_clus PF00172.18 CDO76419.1 - 0.04 14.1 7.7 0.083 13.0 7.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain U79_P34 PF03064.16 CDO76419.1 - 0.33 10.3 10.9 0.6 9.4 10.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4746 PF15928.5 CDO76419.1 - 0.57 9.6 4.1 0.79 9.1 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ATP11 PF06644.11 CDO76419.1 - 1.1 9.0 6.3 2 8.2 6.3 1.4 1 0 0 1 1 1 0 ATP11 protein Vfa1 PF08432.10 CDO76419.1 - 5.2 7.4 12.4 7.5 6.8 12.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Retrotrans_gag PF03732.17 CDO76420.1 - 6.6e-14 52.0 0.0 1.3e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO76420.1 - 4e-10 39.6 0.0 1.1e-09 38.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) Retrotran_gag_2 PF14223.6 CDO76420.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RAP1 PF07218.11 CDO76420.1 - 0.66 8.2 5.4 0.86 7.8 5.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Methyltransf_23 PF13489.6 CDO76421.1 - 3.7e-20 72.4 0.0 7.3e-20 71.5 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO76421.1 - 3.9e-18 65.9 0.0 6.1e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO76421.1 - 4.7e-13 49.7 0.0 1.1e-12 48.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO76421.1 - 5.3e-13 49.5 0.0 1.4e-12 48.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO76421.1 - 2.8e-10 40.2 0.0 2.5e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CDO76421.1 - 1.3e-05 24.6 0.0 0.00021 20.7 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 CDO76421.1 - 0.00059 18.8 0.1 0.0084 15.1 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 CDO76421.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 CDO76421.1 - 0.092 13.1 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 CDO76421.1 - 0.12 11.9 0.1 0.31 10.6 0.1 1.5 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 CDO76421.1 - 0.16 11.3 0.3 0.31 10.4 0.3 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 CDO76421.1 - 0.22 11.1 0.2 1.3 8.6 0.2 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Glyco_hydro_18 PF00704.28 CDO76422.1 - 2e-14 54.0 0.3 2.5e-14 53.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 F-box-like PF12937.7 CDO76424.1 - 4.4e-05 23.3 0.2 0.0024 17.7 0.0 2.8 2 0 0 2 2 2 1 F-box-like zf-CCHH PF10283.9 CDO76424.1 - 0.009 16.0 2.2 0.021 14.8 2.2 1.6 1 0 0 1 1 1 1 PBZ domain F-box PF00646.33 CDO76424.1 - 0.025 14.5 3.4 2.5 8.1 0.0 4.2 4 0 0 4 4 4 0 F-box domain Pkinase PF00069.25 CDO76425.1 - 3.3e-39 134.8 0.0 4.7e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76425.1 - 1.4e-38 132.7 0.0 2.1e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.27 CDO76425.1 - 0.02 14.7 0.1 0.048 13.4 0.1 1.7 1 0 0 1 1 1 0 SAP domain APH PF01636.23 CDO76425.1 - 0.032 14.1 0.1 0.087 12.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO76425.1 - 0.096 11.4 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CDO76425.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Nop14 PF04147.12 CDO76425.1 - 6.8 4.8 21.7 14 3.7 21.7 1.4 1 0 0 1 1 1 0 Nop14-like family RCC1 PF00415.18 CDO76426.1 - 1.2e-57 192.3 6.6 9.9e-09 35.7 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDO76426.1 - 7.2e-36 121.3 30.4 1.2e-06 28.2 0.1 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 CDO76426.1 - 0.012 16.0 1.2 51 4.3 0.0 3.8 4 1 0 4 4 4 0 SUKH-3 immunity protein AMP-binding PF00501.28 CDO76427.1 - 3.7e-55 187.2 0.0 5.6e-27 94.4 0.0 2.1 1 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CDO76427.1 - 4.1e-22 78.9 0.8 9.8e-22 77.7 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 CDO76429.1 - 1.4e-20 73.9 0.0 1.6e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CDO76429.1 - 2.5e-05 23.3 0.0 3.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase AAA PF00004.29 CDO76430.1 - 2.6e-14 53.8 0.0 5.7e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CDO76430.1 - 1.8e-06 28.0 0.0 0.00032 20.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 CDO76430.1 - 4.1e-06 26.8 0.0 0.00018 21.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CDO76430.1 - 8.1e-06 25.7 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CDO76430.1 - 0.00011 21.8 0.0 0.16 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CDO76430.1 - 0.00028 21.3 0.0 0.0013 19.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 CDO76430.1 - 0.00039 20.6 0.1 0.12 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CDO76430.1 - 0.00047 20.4 0.0 0.0067 16.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CDO76430.1 - 0.00055 20.0 0.0 0.00098 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDO76430.1 - 0.0012 19.0 0.0 0.0035 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CDO76430.1 - 0.0048 17.3 0.1 0.014 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CDO76430.1 - 0.0082 16.4 0.0 0.03 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CDO76430.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 CDO76430.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CDO76430.1 - 0.022 14.7 0.1 0.13 12.1 0.0 2.1 1 1 1 2 2 2 0 NTPase AAA_18 PF13238.6 CDO76430.1 - 0.025 15.1 0.0 0.076 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CDO76430.1 - 0.03 14.1 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CDO76430.1 - 0.033 13.4 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 CDO76430.1 - 0.043 13.1 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 CDO76430.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CDO76430.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CLP1_P PF16575.5 CDO76431.1 - 3.7e-35 121.4 0.0 7.3e-35 120.5 0.0 1.5 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 CDO76431.1 - 3e-26 92.1 0.0 6.4e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 SRPRB PF09439.10 CDO76431.1 - 0.064 12.7 0.0 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF3987 PF13148.6 CDO76431.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TniB PF05621.11 CDO76431.1 - 0.13 11.7 0.0 4.3 6.7 0.0 3.0 4 0 0 4 4 4 0 Bacterial TniB protein ATP_bind_1 PF03029.17 CDO76431.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein S-AdoMet_synt_C PF02773.16 CDO76432.1 - 5.7e-68 227.2 0.7 2.2e-67 225.3 0.1 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CDO76432.1 - 1e-47 161.3 0.0 1.9e-47 160.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CDO76432.1 - 3.2e-45 152.9 0.2 3.2e-45 152.9 0.2 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 CDO76432.1 - 0.022 13.6 0.6 0.16 10.7 0.2 2.1 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Myotub-related PF06602.14 CDO76433.1 - 9.3e-149 495.1 0.0 1.1e-148 494.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain HTH_29 PF13551.6 CDO76433.1 - 0.061 13.3 0.1 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix MFS_1 PF07690.16 CDO76435.1 - 1.1e-13 50.9 39.3 1.1e-13 50.9 39.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.12 CDO76435.1 - 0.22 11.7 5.1 2.7 8.2 0.7 3.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Baculo_11_kDa PF06143.11 CDO76435.1 - 0.68 9.6 2.1 14 5.3 2.2 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family Pyr_redox_2 PF07992.14 CDO76438.1 - 2.7e-40 138.5 0.0 6.4e-40 137.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDO76438.1 - 1.8e-10 41.3 0.0 1.4e-06 28.8 0.0 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 CDO76438.1 - 1.8e-10 39.6 1.0 4.7e-05 22.6 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CDO76438.1 - 5.7e-09 36.3 2.9 7.9e-07 29.4 0.7 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CDO76438.1 - 4.2e-08 32.5 0.6 0.0099 15.8 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CDO76438.1 - 1.3e-06 27.6 2.1 0.00036 19.9 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CDO76438.1 - 1.9e-05 24.4 0.7 0.074 12.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.6 CDO76438.1 - 0.0067 15.7 0.2 0.39 9.9 0.4 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_4 PF12763.7 CDO76438.1 - 0.019 14.9 1.3 2.6 8.0 0.1 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand NAD_binding_7 PF13241.6 CDO76438.1 - 0.095 13.1 0.0 0.4 11.2 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding WD40 PF00400.32 CDO76439.1 - 8.9e-33 111.8 7.7 1e-06 29.3 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO76439.1 - 1.1e-11 44.8 1.6 0.13 12.6 0.0 5.2 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CDO76439.1 - 0.01 15.7 0.0 26 4.6 0.1 3.5 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 CDO76439.1 - 0.29 10.1 0.2 5.2 6.0 0.1 2.8 3 1 0 3 3 3 0 Coatomer WD associated region Gti1_Pac2 PF09729.9 CDO76440.1 - 2.9e-30 105.7 1.0 8.9e-28 97.6 0.3 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family cwf18 PF08315.12 CDO76441.1 - 6.9e-14 52.7 9.0 5.5e-12 46.5 9.0 2.2 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor LepA_C PF06421.12 CDO76442.1 - 5.2e-42 142.3 0.0 8.7e-42 141.6 0.0 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CDO76442.1 - 1.6e-12 47.2 0.0 3.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CDO76442.1 - 1.9e-07 31.4 0.0 3.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CDO76442.1 - 5.8e-05 22.9 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 CDO76442.1 - 9e-05 22.5 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Cupredoxin_1 PF13473.6 CDO76443.1 - 0.023 14.8 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Cupredoxin-like domain MSP PF01716.18 CDO76443.1 - 0.073 12.3 0.1 0.082 12.1 0.1 1.1 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide Ecl1 PF12855.7 CDO76444.1 - 9.1 7.4 58.1 0.084 14.0 26.2 3.5 1 1 2 3 3 3 0 ECL1/2/3 zinc binding proteins Vps54 PF07928.12 CDO76445.1 - 3.9e-52 176.3 1.5 3.9e-52 176.3 1.5 2.3 3 0 0 3 3 3 1 Vps54-like protein DUF2451 PF10474.9 CDO76445.1 - 5.9e-07 29.5 1.7 7.1e-07 29.2 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 CDO76445.1 - 0.0021 17.4 0.0 0.0041 16.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Urb2 PF10441.9 CDO76445.1 - 0.11 12.4 0.7 0.33 10.9 0.5 1.9 1 1 0 1 1 1 0 Urb2/Npa2 family RVT_1 PF00078.27 CDO76446.1 - 3.4e-30 105.2 0.0 5e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO76446.1 - 2.2e-09 37.2 0.0 4.8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 CDO76446.1 - 3.9e-07 30.4 0.0 8.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 CDO76446.1 - 0.0028 17.5 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase-like Exo_endo_phos PF03372.23 CDO76446.1 - 0.019 14.5 5.8 0.01 15.3 2.3 2.4 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Chromo PF00385.24 CDO76448.1 - 1.1e-07 31.6 0.1 1.8e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4407 PF14362.6 CDO76449.1 - 0.64 9.3 15.4 0.88 8.9 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Coilin_N PF15862.5 CDO76449.1 - 6.1 6.6 11.1 0.21 11.4 4.2 1.9 2 0 0 2 2 2 0 Coilin N-terminus Retrotrans_gag PF03732.17 CDO76450.1 - 2.2e-08 34.3 0.0 5.2e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 CDO76450.1 - 0.025 14.3 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_6 PF15288.6 CDO76450.1 - 0.49 10.3 2.6 1.5 8.7 2.6 1.9 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.11 CDO76451.1 - 3.3e-07 30.1 0.0 7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDO76451.1 - 1.6e-06 28.7 0.0 3.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 CDO76451.1 - 3.4e-05 23.5 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 CDO76451.1 - 0.0026 18.3 0.0 0.0045 17.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 CDO76451.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase zf-RVT PF13966.6 CDO76452.1 - 4.3e-06 27.3 0.0 7.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Abhydrolase_3 PF07859.13 CDO76453.1 - 7.3e-50 169.8 0.1 9.3e-50 169.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CDO76453.1 - 0.09 11.6 0.0 0.16 10.8 0.0 1.4 2 0 0 2 2 2 0 Carboxylesterase family Histone PF00125.24 CDO76454.1 - 8.6e-24 84.4 0.8 1.1e-23 84.0 0.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDO76454.1 - 2.3e-06 27.8 0.1 6.6e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CDO76454.1 - 0.0003 21.2 0.0 0.00055 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.11 CDO76454.1 - 0.09 12.4 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein YscO-like PF16789.5 CDO76454.1 - 0.11 12.6 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein Histone PF00125.24 CDO76455.1 - 7.7e-18 65.1 0.0 1e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDO76455.1 - 1.6e-17 62.9 0.8 3.5e-17 61.8 0.8 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CDO76455.1 - 1.3e-06 28.6 0.0 1.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HECT_2 PF09814.9 CDO76456.1 - 4.4e-48 164.0 0.0 6.6e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RRM_1 PF00076.22 CDO76457.1 - 5.3e-31 106.3 0.0 1.7e-19 69.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.24 CDO76458.1 - 5.6e-18 65.6 0.0 7.6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CDO76458.1 - 4.3e-17 61.6 0.3 9.2e-17 60.5 0.3 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CDO76458.1 - 1.3e-06 28.6 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CDO76459.1 - 2.9e-16 60.0 5.9 2.9e-15 56.8 0.1 2.1 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CDO76459.1 - 4.2e-05 23.7 0.1 0.0001 22.5 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CDO76459.1 - 0.00034 21.0 0.0 0.00066 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.11 CDO76459.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein GST_C_3 PF14497.6 CDO76460.1 - 3e-26 91.5 0.3 5e-26 90.8 0.3 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDO76460.1 - 8.8e-05 22.7 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CDO76460.1 - 0.033 14.5 0.0 0.15 12.4 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CDO76460.1 - 0.095 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Homoserine_dh PF00742.19 CDO76461.1 - 3.9e-47 160.4 0.0 5.1e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CDO76461.1 - 4.7e-17 62.7 0.0 8e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PHB_acc_N PF07879.11 CDO76461.1 - 0.15 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain WD40 PF00400.32 CDO76462.1 - 1.6e-11 44.5 11.5 1.4e-05 25.7 0.0 5.5 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO76462.1 - 2.7e-07 30.8 0.4 0.086 13.1 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain EamA PF00892.20 CDO76462.1 - 0.15 12.3 11.7 0.27 11.4 11.7 1.4 1 0 0 1 1 1 0 EamA-like transporter family GRAB PF10375.9 CDO76463.1 - 1e-06 28.3 1.2 2e-06 27.5 1.2 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.20 CDO76463.1 - 0.00011 22.1 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 GRIP domain GldM_N PF12081.8 CDO76463.1 - 0.011 15.9 16.3 0.045 13.9 4.6 2.3 1 1 1 2 2 2 0 GldM N-terminal domain DUF2935 PF11155.8 CDO76463.1 - 0.042 14.2 1.1 0.89 9.9 0.6 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF1722 PF08349.11 CDO76463.1 - 0.62 10.4 6.5 8.4 6.7 0.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1722) CENP-F_leu_zip PF10473.9 CDO76463.1 - 3 7.9 52.2 1.4 8.9 17.2 4.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERG2_Sigma1R PF04622.12 CDO76464.1 - 7e-91 303.2 0.0 8.4e-91 303.0 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ERG2_Sigma1R PF04622.12 CDO76466.1 - 3e-92 307.7 0.0 5.1e-92 306.9 0.0 1.4 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein VPR PF00522.18 CDO76466.1 - 0.0033 17.4 0.1 5.1 7.2 0.0 3.0 3 0 0 3 3 3 2 VPR/VPX protein DUF2207 PF09972.9 CDO76466.1 - 1.2 7.9 3.6 1.9 7.1 3.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPC25 PF06703.11 CDO76467.1 - 3.2e-51 173.3 0.0 3.7e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) PNRC PF15365.6 CDO76468.1 - 3e-06 26.9 2.7 3e-06 26.9 2.7 4.2 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif Phage_integrase PF00589.22 CDO76469.1 - 0.0033 17.3 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family zf-CCCH_3 PF15663.5 CDO76471.1 - 0.03 14.5 0.8 0.073 13.3 0.8 1.6 1 0 0 1 1 1 0 Zinc-finger containing family Retrotrans_gag PF03732.17 CDO76473.1 - 1e-12 48.1 0.1 5e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO76473.1 - 2.2e-06 27.5 0.1 6.4e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 CDO76473.1 - 0.24 11.5 0.4 0.38 10.9 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle SOG2 PF10428.9 CDO76473.1 - 1.1 8.4 11.1 1.4 8.0 11.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 CDO76473.1 - 1.3 7.8 8.2 1.5 7.5 8.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM199X PF15814.5 CDO76473.1 - 1.7 7.7 10.6 2.2 7.2 10.6 1.1 1 0 0 1 1 1 0 Protein family FAM199X NPR3 PF03666.13 CDO76473.1 - 3.8 6.2 7.4 6.5 5.4 7.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4551 PF15087.6 CDO76473.1 - 6.7 5.4 6.6 7.4 5.3 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RT_RNaseH PF17917.1 CDO76474.1 - 1.5e-37 128.1 0.0 1.9e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO76474.1 - 1.7e-31 108.2 0.0 2.9e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Raptor_N PF14538.6 CDO76475.1 - 8.7e-61 204.2 0.0 1.6e-60 203.3 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CDO76475.1 - 3.6e-05 23.7 0.1 0.0012 18.9 0.0 3.5 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 CDO76475.1 - 5.3e-05 23.6 0.6 0.00053 20.4 0.0 3.0 3 0 0 3 3 3 1 HEAT-like repeat WD40 PF00400.32 CDO76475.1 - 0.0023 18.7 2.1 15 6.7 0.0 4.3 3 0 0 3 3 3 1 WD domain, G-beta repeat HEAT_2 PF13646.6 CDO76475.1 - 0.0048 17.3 0.0 0.042 14.3 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats ANAPC4_WD40 PF12894.7 CDO76475.1 - 0.023 15.0 0.1 2.6 8.4 0.0 2.6 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 CDO76475.1 - 0.027 14.5 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Peptidase_C14 PF00656.22 CDO76475.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Caspase domain Arm PF00514.23 CDO76475.1 - 0.076 13.1 0.2 0.48 10.6 0.1 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Dynactin PF12455.8 CDO76476.1 - 6.7e-94 314.3 5.9 6.7e-94 314.3 5.9 3.2 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 CDO76476.1 - 5.4e-24 84.0 0.4 1.7e-23 82.4 0.3 1.8 2 0 0 2 2 2 1 CAP-Gly domain MAD PF05557.13 CDO76476.1 - 0.0025 16.3 10.6 0.0025 16.3 10.6 4.1 2 1 1 3 3 3 1 Mitotic checkpoint protein ABC_tran PF00005.27 CDO76478.1 - 6.3e-51 172.5 0.0 2.1e-26 93.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CDO76478.1 - 1.3e-22 80.4 45.2 1.4e-14 54.0 24.2 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CDO76478.1 - 8.8e-15 55.3 0.7 6.6e-05 22.9 0.0 3.9 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDO76478.1 - 1.2e-06 29.2 3.4 0.0049 17.4 0.6 2.2 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 CDO76478.1 - 0.00012 21.8 0.1 0.33 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CDO76478.1 - 0.00013 21.6 0.7 0.27 11.0 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF4162 PF13732.6 CDO76478.1 - 0.00033 21.3 0.0 1.3 9.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) Rad17 PF03215.15 CDO76478.1 - 0.0012 18.8 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain SMC_N PF02463.19 CDO76478.1 - 0.0023 17.4 4.0 1.7 8.0 0.1 3.9 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CDO76478.1 - 0.0023 17.9 0.2 2.5 8.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 CDO76478.1 - 0.0033 17.2 0.5 3.7 7.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain SRP54 PF00448.22 CDO76478.1 - 0.0041 16.8 1.1 1.4 8.5 0.2 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain MukB PF04310.12 CDO76478.1 - 0.0089 15.9 0.7 4.4 7.0 0.1 2.4 2 0 0 2 2 2 2 MukB N-terminal AAA_15 PF13175.6 CDO76478.1 - 0.015 15.0 0.0 4.7 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 CDO76478.1 - 0.026 13.8 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 CDO76478.1 - 0.055 12.5 0.0 7.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 CDO76478.1 - 0.066 13.5 0.6 13 6.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CDO76478.1 - 0.083 13.1 0.3 7.7 6.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CDO76478.1 - 0.084 13.3 0.4 15 6.0 0.1 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GRAM PF02893.20 CDO76479.1 - 2.8e-22 78.8 0.0 4.9e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 GRAM domain VASt PF16016.5 CDO76479.1 - 1.7e-17 64.2 0.4 1.3e-16 61.3 0.0 2.3 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain YoaP PF14268.6 CDO76479.1 - 0.16 11.5 0.5 0.33 10.5 0.5 1.5 1 0 0 1 1 1 0 YoaP-like Pkinase PF00069.25 CDO76480.1 - 3.2e-58 197.2 0.0 3.6e-57 193.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76480.1 - 2e-25 89.5 0.0 3e-15 56.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 CDO76480.1 - 0.00026 21.6 6.7 0.00026 21.6 6.7 3.3 3 0 0 3 3 3 1 Protein kinase C terminal domain FTA2 PF13095.6 CDO76480.1 - 0.0014 18.3 0.0 0.16 11.6 0.0 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 PX PF00787.24 CDO76480.1 - 0.0029 17.6 0.0 0.034 14.1 0.0 2.5 1 1 0 1 1 1 1 PX domain Kdo PF06293.14 CDO76480.1 - 0.0083 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO76480.1 - 0.052 13.5 1.2 5.1 7.0 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CDO76480.1 - 0.069 12.5 0.0 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Kinase-like MCLC PF05934.11 CDO76481.1 - 4.9 5.8 4.2 11 4.6 4.2 1.5 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Thioredoxin PF00085.20 CDO76482.1 - 7.2e-25 87.0 0.5 2.6e-20 72.3 0.1 2.0 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 CDO76482.1 - 9.1e-05 22.7 0.0 0.00013 22.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CDO76482.1 - 0.00013 21.8 0.1 0.00021 21.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CDO76482.1 - 0.00013 21.9 0.1 0.00028 20.8 0.1 1.5 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CDO76482.1 - 0.00061 20.2 0.1 0.0018 18.7 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CDO76482.1 - 0.061 12.7 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 CDO76482.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Toxin-deaminase PF14424.6 CDO76482.1 - 0.076 13.1 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases Redoxin PF08534.10 CDO76482.1 - 0.081 12.6 0.3 0.21 11.3 0.2 1.7 1 1 1 2 2 2 0 Redoxin Ig_mannosidase PF17753.1 CDO76483.1 - 5.1e-13 48.6 0.3 1.6e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 CDO76483.1 - 1.7e-11 44.6 0.9 5.3e-11 43.0 0.9 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 CDO76483.1 - 0.0012 19.5 0.0 0.0062 17.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 CDO76483.1 - 0.018 14.9 0.0 0.38 10.6 0.0 3.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain Chitin_synth_2 PF03142.15 CDO76484.1 - 9.8e-131 436.9 0.0 1.4e-130 436.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CDO76484.1 - 6.1e-06 26.3 0.8 1.3e-05 25.3 0.8 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CDO76484.1 - 0.068 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 CDO76485.1 - 1.7e-115 386.7 0.0 3e-115 385.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Glycos_transf_2 PF00535.26 CDO76485.1 - 0.097 12.5 0.0 0.8 9.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CDO76485.1 - 0.18 11.3 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CDO76485.1 - 0.18 11.6 0.1 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Bac_chlorC PF02043.17 CDO76485.1 - 1.7 8.7 3.8 9.4 6.3 1.2 2.6 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein CRAL_TRIO PF00650.20 CDO76486.1 - 8.2e-41 139.4 0.0 1.1e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CDO76486.1 - 3.5e-05 24.0 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CDO76486.1 - 0.00011 22.3 0.7 0.0002 21.5 0.7 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Fibrillin_U_N PF18193.1 CDO76487.1 - 0.33 11.1 3.1 3.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Fibrillin 1 unique N-terminal domain DUF3140 PF11338.8 CDO76488.1 - 3.2e-25 88.4 0.6 3.2e-25 88.4 0.6 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3140) O-FucT PF10250.9 CDO76489.1 - 7.8e-08 32.4 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Ribosomal_L28e PF01778.17 CDO76490.1 - 3.9e-30 104.9 0.0 5.3e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family FMN_bind_2 PF04299.12 CDO76492.1 - 2.9e-59 199.6 0.0 3.4e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Retrotran_gag_2 PF14223.6 CDO76493.1 - 0.0021 17.7 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO76493.1 - 0.028 14.5 1.4 0.056 13.5 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDO76493.1 - 0.064 13.0 0.9 0.15 11.8 0.9 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger rve PF00665.26 CDO76494.1 - 1.6e-11 44.4 0.0 2.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO76494.1 - 1.3e-07 31.4 0.0 2.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO76494.1 - 0.0032 17.2 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Asp PF00026.23 CDO76496.1 - 6e-61 206.6 0.1 5.1e-47 160.8 1.1 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO76496.1 - 8.2e-09 35.9 8.7 7.8e-06 26.2 0.2 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO76496.1 - 0.032 14.9 0.0 0.096 13.3 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Glyco_hydro_15 PF00723.21 CDO76497.1 - 1.1e-50 172.7 0.0 1.3e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Dynactin_p62 PF05502.13 CDO76498.1 - 4.8e-49 167.4 0.3 4.3e-28 98.3 0.1 2.1 1 1 0 2 2 2 2 Dynactin p62 family Phosphodiest PF01663.22 CDO76499.1 - 1.8e-53 182.4 2.6 1.2e-44 153.4 1.3 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase PBP1_TM PF14812.6 CDO76499.1 - 0.013 15.8 0.2 0.025 14.9 0.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Asp PF00026.23 CDO76500.1 - 9.8e-24 84.3 0.2 2.3e-17 63.4 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CDO76500.1 - 0.03 14.9 0.2 0.34 11.6 0.2 2.8 2 2 0 2 2 2 0 Aspartyl protease TAXi_N PF14543.6 CDO76500.1 - 0.033 14.4 0.5 6 7.1 0.0 2.3 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 CDO76500.1 - 0.033 14.7 0.1 0.87 10.2 0.0 2.9 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease DUF2970 PF11174.8 CDO76500.1 - 0.083 12.8 0.6 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) SIT PF15330.6 CDO76500.1 - 0.11 13.0 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4381 PF14316.6 CDO76500.1 - 0.29 11.4 2.3 0.56 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Asp PF00026.23 CDO76501.1 - 9.3e-10 38.4 0.0 5.2e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Ribosomal_S10 PF00338.22 CDO76502.1 - 1e-28 99.4 0.4 1.3e-28 99.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF572 PF04502.13 CDO76503.1 - 8.9e-71 239.2 0.1 1.1e-70 239.0 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) PE PF00934.20 CDO76503.1 - 0.16 12.3 1.2 0.22 11.9 0.2 1.7 2 0 0 2 2 2 0 PE family DUF1682 PF07946.14 CDO76503.1 - 1.8 7.7 7.4 2.4 7.3 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) cobW PF02492.19 CDO76504.1 - 1.4e-24 86.7 1.0 4.8e-23 81.6 1.0 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DnaJ PF00226.31 CDO76504.1 - 7.4e-17 61.2 0.0 1.5e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain AAA_16 PF13191.6 CDO76504.1 - 0.024 15.0 0.0 0.31 11.4 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain MobB PF03205.14 CDO76504.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Fungal_trans PF04082.18 CDO76505.1 - 2.8e-13 49.5 0.0 4.4e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNARE_assoc PF09335.11 CDO76506.1 - 8.3e-11 42.4 4.9 8.3e-11 42.4 4.9 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein ARID PF01388.21 CDO76507.1 - 7e-10 39.4 1.0 3.3e-09 37.3 0.0 2.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain CorA PF01544.18 CDO76507.1 - 0.02 14.2 0.6 0.046 13.0 0.6 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1840 PF08895.11 CDO76507.1 - 0.12 12.7 19.9 0.032 14.6 4.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Adaptin_N PF01602.20 CDO76508.1 - 1.3e-116 390.3 0.2 3.9e-116 388.7 0.2 1.6 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CDO76508.1 - 1.5e-13 51.1 2.2 4.7e-12 46.2 0.0 3.5 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CDO76508.1 - 7.2e-11 42.3 1.7 0.00031 21.1 0.0 4.5 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 CDO76508.1 - 9e-05 22.4 4.6 0.45 10.9 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat MOR2-PAG1_C PF14225.6 CDO76508.1 - 0.025 14.5 0.4 4.7 7.0 0.1 2.3 2 0 0 2 2 2 0 Cell morphogenesis C-terminal HEAT_EZ PF13513.6 CDO76508.1 - 0.04 14.4 0.7 1.2e+02 3.3 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat Frag1 PF10277.9 CDO76509.1 - 1.1e-22 80.7 8.7 2.7e-22 79.4 1.3 2.5 1 1 1 2 2 2 2 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 CDO76509.1 - 0.065 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Amino_oxidase PF01593.24 CDO76511.1 - 1.3e-54 186.3 0.3 4e-52 178.0 0.3 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDO76511.1 - 2.5e-10 40.4 0.1 9e-10 38.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDO76511.1 - 9.5e-07 28.3 0.1 0.00082 18.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDO76511.1 - 0.00039 19.9 1.1 0.00072 19.0 1.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDO76511.1 - 0.0006 19.0 0.2 0.0012 18.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CDO76511.1 - 0.00065 19.0 0.5 0.00065 19.0 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 CDO76511.1 - 0.00082 18.7 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CDO76511.1 - 0.00099 19.6 1.0 0.066 13.8 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDO76511.1 - 0.0032 17.1 4.7 0.012 15.3 1.4 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CDO76511.1 - 0.041 13.1 0.8 0.075 12.3 0.3 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CDO76511.1 - 0.086 11.9 0.8 2.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 CDO76511.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_2 PF02230.16 CDO76512.1 - 2e-10 40.9 0.0 3.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CDO76512.1 - 0.0053 17.4 0.0 0.0063 17.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CDO76512.1 - 0.079 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 CDO76513.1 - 1.6e-11 44.3 0.0 2.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO76513.1 - 4.3e-08 34.0 0.9 4.3e-08 34.0 0.9 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO76513.1 - 0.00044 19.6 0.1 0.0037 16.6 0.0 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 HSP20 PF00011.21 CDO76514.1 - 2.1e-24 85.6 0.1 2.7e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDO76514.1 - 7.1e-10 38.3 0.0 1.1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 CDO76514.1 - 0.01 16.8 0.0 0.017 16.1 0.0 1.3 1 0 0 1 1 1 0 CS domain VLPT PF07122.11 CDO76514.1 - 0.13 12.0 0.2 0.53 10.1 0.2 2.0 1 1 0 1 1 1 0 Variable length PCR target protein (VLPT) EloA-BP1 PF15870.5 CDO76515.1 - 0.0039 17.5 0.1 0.0039 17.5 0.1 1.9 2 0 0 2 2 2 1 ElonginA binding-protein 1 RRP7 PF12923.7 CDO76515.1 - 0.049 13.8 2.2 0.091 12.9 2.2 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Alpha-amylase PF00128.24 CDO76516.1 - 8.1e-59 199.9 0.4 1.5e-58 199.0 0.4 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 CDO76516.1 - 4.5e-16 58.9 0.2 9.4e-16 57.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 CDO76516.1 - 0.0092 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Aminotran_5 PF00266.19 CDO76516.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Agglutinin_C PF18021.1 CDO76517.1 - 3e-37 127.0 0.1 5.1e-37 126.3 0.1 1.4 1 0 0 1 1 1 1 Agglutinin C-terminal Lectin_C_term PF18022.1 CDO76517.1 - 2.6e-34 117.7 0.1 4.1e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin C-terminal domain RicinB_lectin_2 PF14200.6 CDO76517.1 - 9.3e-28 96.8 13.6 1.3e-14 54.7 1.1 3.0 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 CDO76517.1 - 0.011 16.0 0.0 1.4 9.2 0.2 2.5 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain WD40 PF00400.32 CDO76518.1 - 1.5e-27 95.2 20.6 4.6e-05 24.1 0.5 11.0 11 1 1 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO76518.1 - 1.3e-15 57.5 0.1 0.036 14.4 0.0 7.2 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDO76518.1 - 2.5e-05 23.8 0.0 0.022 14.1 0.0 2.8 3 0 0 3 3 3 2 WD40-like domain PD40 PF07676.12 CDO76518.1 - 0.00059 19.7 1.6 3.6 7.6 0.0 4.9 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 CDO76518.1 - 0.0019 18.2 0.0 1 9.4 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat NACHT PF05729.12 CDO76519.1 - 4.8e-06 26.6 0.2 0.00067 19.6 0.2 2.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CDO76519.1 - 0.0033 17.8 0.1 0.012 16.0 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain DUF659 PF04937.15 CDO76520.1 - 2.2e-08 34.1 0.1 4.2e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF3306 PF11748.8 CDO76520.1 - 0.1 13.5 0.3 0.1 13.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Not1 PF04054.15 CDO76521.1 - 2.8e-129 431.2 0.0 5.2e-129 430.4 0.0 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CDO76521.1 - 2.2e-94 315.1 0.3 5.1e-92 307.3 0.1 2.7 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 CDO76521.1 - 1.9e-55 186.8 0.1 4.2e-55 185.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 CDO76521.1 - 2.6e-51 173.5 0.0 5.5e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 CDO76521.1 - 8.9e-47 158.9 0.1 2.7e-46 157.4 0.1 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Peptidase_S9 PF00326.21 CDO76522.1 - 1.3e-06 28.1 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CDO76522.1 - 2e-05 24.5 0.0 0.012 15.5 0.0 2.6 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase MFS_1 PF07690.16 CDO76524.1 - 5.7e-26 91.3 39.1 2.7e-23 82.5 23.4 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily GtrA PF04138.14 CDO76524.1 - 2.7 8.3 7.8 0.35 11.1 1.9 2.5 1 1 1 2 2 2 0 GtrA-like protein Glyco_hydro_63 PF03200.16 CDO76526.1 - 2.1e-94 317.1 0.0 9.9e-63 212.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CDO76526.1 - 4.3e-77 259.2 0.0 1.8e-76 257.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain NYN PF01936.18 CDO76527.1 - 1e-27 97.4 0.0 1.7e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 NYN domain Sulfate_transp PF00916.20 CDO76528.1 - 5.8e-115 384.1 9.4 8.4e-115 383.5 9.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CDO76528.1 - 1.8e-12 47.0 0.0 3.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CDO76528.1 - 0.003 17.9 13.8 0.0046 17.3 2.2 3.0 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 CDO76528.1 - 0.029 14.7 0.0 0.088 13.2 0.0 1.8 1 0 0 1 1 1 0 STAS domain Sulfate_transp PF00916.20 CDO76529.1 - 2.9e-112 375.2 13.1 3.8e-112 374.8 13.1 1.1 1 0 0 1 1 1 1 Sulfate permease family Transcrip_reg PF01709.20 CDO76529.1 - 6.5e-47 160.0 2.1 2.9e-24 85.8 0.0 2.2 1 1 1 2 2 2 2 Transcriptional regulator STAS PF01740.21 CDO76529.1 - 6.7e-12 45.1 0.0 1.5e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CDO76529.1 - 0.0014 19.0 15.0 0.0019 18.6 3.7 2.7 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 CDO76529.1 - 0.0087 16.4 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 STAS domain WD40 PF00400.32 CDO76530.1 - 4.5e-27 93.8 18.5 1.2e-10 41.8 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO76530.1 - 9.5e-07 29.0 0.0 0.0077 16.5 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CDO76530.1 - 0.00073 18.6 0.1 0.018 14.0 0.0 2.9 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NYN PF01936.18 CDO76531.1 - 5.4e-20 72.4 0.0 9.1e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 NYN domain PIN_4 PF13638.6 CDO76532.1 - 1.1e-06 29.0 0.0 1.5e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 PIN domain PhdYeFM_antitox PF02604.19 CDO76532.1 - 0.21 11.4 0.9 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Sugar_tr PF00083.24 CDO76533.1 - 5.1e-124 414.6 25.1 5.9e-124 414.4 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO76533.1 - 4.5e-22 78.4 43.6 1.1e-16 60.7 13.7 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily YtpI PF14007.6 CDO76533.1 - 4 7.7 8.9 0.64 10.2 0.4 3.5 4 0 0 4 4 4 0 YtpI-like protein Transposase_21 PF02992.14 CDO76536.1 - 5.2e-12 45.5 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 RVT_1 PF00078.27 CDO76537.1 - 2.2e-23 82.9 0.1 4.8e-22 78.6 0.1 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO76537.1 - 2.2e-20 73.3 0.0 5.2e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 RNase H FlxA PF14282.6 CDO76537.1 - 0.08 12.9 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 FlxA-like protein HTH_Tnp_Tc3_2 PF01498.18 CDO76537.1 - 0.13 12.5 0.0 1.1 9.5 0.0 2.6 3 0 0 3 3 3 0 Transposase UCH_C PF18031.1 CDO76537.1 - 0.2 11.6 0.5 0.44 10.5 0.5 1.6 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases Abhydrolase_3 PF07859.13 CDO76538.1 - 5.6e-29 101.5 0.0 1.8e-20 73.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CDO76538.1 - 0.015 14.1 0.0 0.042 12.7 0.0 1.6 2 0 0 2 2 2 0 Steryl acetyl hydrolase GrpE PF01025.19 CDO76538.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 GrpE Allantoicase PF03561.15 CDO76539.1 - 3.7e-91 302.6 0.0 1.3e-45 154.9 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 CDO76539.1 - 1.7e-47 161.6 0.0 1.6e-46 158.5 0.0 2.0 1 1 0 2 2 2 1 Ureidoglycolate lyase F5_F8_type_C PF00754.25 CDO76539.1 - 0.00015 21.8 0.0 0.011 15.9 0.0 2.7 2 0 0 2 2 2 1 F5/8 type C domain BPL_N PF09825.9 CDO76540.1 - 3.9e-44 151.3 0.0 1.1e-22 80.6 0.0 2.1 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 CDO76540.1 - 2.2e-22 79.3 0.0 3.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SUZ PF12752.7 CDO76541.1 - 1.4e-14 54.6 3.0 1.4e-14 54.6 3.0 2.4 2 1 0 2 2 2 1 SUZ domain Promethin PF16015.5 CDO76541.1 - 3.1e-07 30.3 23.0 5.4e-07 29.5 23.0 1.3 1 0 0 1 1 1 1 Promethin DUF3927 PF13064.6 CDO76541.1 - 7.2 6.7 10.0 6.2 6.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3927) GFO_IDH_MocA PF01408.22 CDO76542.1 - 3.5e-21 76.2 0.7 6.3e-21 75.4 0.7 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CDO76542.1 - 4.7e-05 23.4 0.0 0.00078 19.4 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 CDO76542.1 - 0.041 14.5 0.1 0.12 13.0 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 CDO76542.1 - 0.041 14.1 0.9 0.079 13.2 0.9 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CDT1_C PF16679.5 CDO76543.1 - 4.1e-13 49.6 0.0 1e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Sugar_tr PF00083.24 CDO76544.1 - 2e-95 320.4 21.7 6e-73 246.2 8.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDO76544.1 - 1.4e-17 63.7 37.9 2e-07 30.3 5.2 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily zf-CCCH PF00642.24 CDO76545.1 - 0.0063 16.4 12.0 0.1 12.6 3.7 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tnp_22_trimer PF17489.2 CDO76545.1 - 0.035 14.1 0.1 0.071 13.1 0.1 1.5 1 0 0 1 1 1 0 L1 transposable element trimerization domain zf_CCCH_4 PF18345.1 CDO76545.1 - 0.04 14.0 2.0 0.04 14.0 2.0 2.5 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 CDO76545.1 - 8.6 6.3 12.8 0.2 11.5 1.2 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Rho_GDI PF02115.17 CDO76546.1 - 1.2e-48 165.5 0.0 1.4e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP_dimer PF03717.15 CDO76546.1 - 0.046 14.1 0.1 0.083 13.2 0.0 1.5 1 1 1 2 2 2 0 Penicillin-binding Protein dimerisation domain CopC PF04234.12 CDO76546.1 - 0.049 14.7 0.0 0.086 13.9 0.0 1.5 1 0 0 1 1 1 0 CopC domain E1_DerP2_DerF2 PF02221.15 CDO76546.1 - 0.19 12.1 0.1 0.53 10.7 0.1 1.7 1 1 0 1 1 1 0 ML domain RIX1 PF08167.12 CDO76547.1 - 8.3e-19 68.1 0.4 8.3e-19 68.1 0.4 2.0 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Usg PF06233.12 CDO76547.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Usg-like family DUF5102 PF17104.5 CDO76549.1 - 1.5e-08 35.1 0.2 1.8e-08 34.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) RNA_pol_Rpb1_5 PF04998.17 CDO76550.1 - 3.4e-81 272.6 0.0 6.8e-81 271.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CDO76550.1 - 3.3e-63 212.9 0.0 5.7e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CDO76550.1 - 2.3e-37 128.3 0.0 4.9e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CDO76550.1 - 5.2e-10 39.2 0.2 0.0025 17.2 0.0 3.6 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 CDO76550.1 - 4.3e-05 23.4 0.0 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RRM_1 PF00076.22 CDO76551.1 - 3e-19 68.6 0.1 3e-19 68.6 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDO76551.1 - 1.4e-08 34.4 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDO76551.1 - 0.037 14.1 0.2 0.065 13.3 0.2 1.4 1 1 0 1 1 1 0 RNA binding motif RRM_8 PF11835.8 CDO76551.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 1 1 2 2 2 0 RRM-like domain RRM_occluded PF16842.5 CDO76551.1 - 0.079 12.8 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 CDO76551.1 - 0.1 12.8 0.2 0.4 10.9 0.0 1.9 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter PBP PF01161.20 CDO76552.1 - 2.2e-13 50.7 0.0 3.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DEAD PF00270.29 CDO76554.1 - 1.7e-43 148.4 0.1 3.3e-43 147.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO76554.1 - 3.3e-32 111.1 0.1 1.4e-31 109.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CDO76554.1 - 0.00023 21.5 0.1 0.017 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CDO76554.1 - 0.00034 20.7 0.0 0.00083 19.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CDO76554.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CDO76554.1 - 0.028 14.7 0.3 0.13 12.6 0.3 2.0 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 CDO76554.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.25 CDO76554.1 - 0.13 11.6 0.0 0.47 9.7 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DUF3449 PF11931.8 CDO76555.1 - 6.1e-74 247.8 0.3 6.1e-74 247.8 0.3 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 CDO76555.1 - 4.7e-26 91.1 2.6 7.9e-26 90.4 0.7 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 CDO76555.1 - 5.3e-08 32.9 0.7 5.3e-08 32.9 0.7 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDO76555.1 - 1.3e-07 31.8 7.6 4.3e-07 30.1 1.8 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 CDO76555.1 - 7.7e-07 28.9 0.0 1.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.7 CDO76555.1 - 0.0056 17.0 5.8 0.064 13.6 1.0 2.9 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 CDO76555.1 - 0.017 15.2 3.5 0.99 9.6 0.1 3.0 2 0 0 2 2 2 0 DBF zinc finger Laps PF10169.9 CDO76555.1 - 0.42 11.2 6.8 0.26 11.9 0.4 2.7 2 0 0 2 2 2 0 Learning-associated protein Syja_N PF02383.18 CDO76556.1 - 4.9e-63 213.4 0.0 6.7e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain adh_short PF00106.25 CDO76558.1 - 5.8e-43 146.6 0.2 8.4e-43 146.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO76558.1 - 1.4e-28 100.1 0.0 2.1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO76558.1 - 2.3e-13 50.5 0.9 5e-12 46.1 0.9 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO76558.1 - 0.013 15.0 0.1 0.023 14.2 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2316 PF10078.9 CDO76558.1 - 0.076 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) TFR_dimer PF04253.15 CDO76560.1 - 5.5e-24 84.6 1.1 5.8e-20 71.6 0.1 2.6 2 0 0 2 2 2 2 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CDO76560.1 - 6.8e-15 55.3 0.0 1.2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CDO76560.1 - 1.3e-08 34.7 0.0 3.4e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 PA domain BRE1 PF08647.11 CDO76560.1 - 4.6 7.4 6.8 2.8 8.1 0.2 2.5 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Alpha-amylase_C PF02806.18 CDO76561.1 - 1.1e-22 80.3 0.2 6.2e-21 74.7 0.2 2.7 1 1 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CDO76561.1 - 1.4e-16 60.6 0.1 3.3e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CDO76561.1 - 7.1e-15 55.4 0.1 6.3e-11 42.4 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Spermine_synth PF01564.17 CDO76562.1 - 1.7e-06 27.6 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain BTB PF00651.31 CDO76563.1 - 0.00058 20.1 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SAP PF02037.27 CDO76566.1 - 9.7e-08 31.6 0.8 2.3e-07 30.4 0.5 1.8 2 0 0 2 2 2 1 SAP domain Spherulin4 PF12138.8 CDO76567.1 - 3.9e-50 170.7 0.0 4.5e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 ubiquitin PF00240.23 CDO76568.1 - 1.1e-08 34.7 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 CDO76568.1 - 0.036 14.6 0.0 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF4605 PF15378.6 CDO76568.1 - 0.059 13.2 1.3 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) Rad60-SLD PF11976.8 CDO76568.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Sde2_N_Ubi PF13019.6 CDO76568.1 - 1.3 8.9 0.0 1.3 8.9 0.0 3.0 3 0 0 3 3 3 0 Silencing defective 2 N-terminal ubiquitin domain cNMP_binding PF00027.29 CDO76569.1 - 1.7e-34 117.8 1.6 7.9e-17 61.1 0.0 3.6 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CDO76569.1 - 9.9e-07 28.3 0.5 3.7e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit Apt1 PF10351.9 CDO76570.1 - 0.11 11.3 7.7 0.16 10.8 7.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 CDO76570.1 - 2.8 5.0 10.6 3.7 4.5 10.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glyco_hydro_61 PF03443.14 CDO76571.1 - 2.4e-51 174.6 0.0 3e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 CDO76572.1 - 2.8e-35 121.9 13.1 2.4e-33 115.5 14.7 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 CDO76572.1 - 0.00027 20.4 1.7 0.00027 20.4 1.7 2.7 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF4381 PF14316.6 CDO76572.1 - 0.016 15.5 0.0 0.016 15.5 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF2109 PF09882.9 CDO76572.1 - 0.14 12.2 2.0 0.43 10.6 2.0 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) Dimer_Tnp_hAT PF05699.14 CDO76573.1 - 2.4e-15 56.1 0.0 6.6e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 CDO76574.1 - 1.9e-06 27.8 0.0 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) SMC_N PF02463.19 CDO76576.1 - 6.4e-67 225.2 0.0 2.4e-66 223.3 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CDO76576.1 - 3.9e-20 72.3 0.3 1.9e-19 70.1 0.1 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CDO76576.1 - 3.6e-13 50.5 11.7 3.6e-13 50.5 11.7 6.9 2 2 0 3 3 1 1 AAA domain AAA_21 PF13304.6 CDO76576.1 - 5.5e-12 46.1 0.6 5.9e-05 23.0 0.1 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CDO76576.1 - 2.7e-07 30.6 26.4 6.9e-07 29.3 0.0 3.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CDO76576.1 - 7.1e-05 22.5 0.1 0.00023 20.9 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 CDO76576.1 - 0.00052 20.3 19.4 0.00052 20.3 19.4 7.1 4 3 1 5 5 5 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CDO76576.1 - 0.043 12.7 102.9 0.0066 15.4 15.7 6.5 3 2 3 6 6 6 0 Spc7 kinetochore protein PhoU PF01895.19 CDO76576.1 - 0.11 13.0 0.2 0.11 13.0 0.2 4.8 5 1 0 5 5 5 0 PhoU domain ABC_tran PF00005.27 CDO76576.1 - 0.48 10.9 34.1 3.3 8.2 2.7 6.9 2 2 1 3 3 3 0 ABC transporter Cob_adeno_trans PF01923.18 CDO76576.1 - 0.65 10.1 38.8 1.8 8.7 3.4 6.7 3 2 4 7 7 7 0 Cobalamin adenosyltransferase DUF2163 PF09931.9 CDO76576.1 - 5.5 7.2 7.3 6.5 6.9 0.7 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2163) DUF572 PF04502.13 CDO76577.1 - 2.7 7.5 9.6 3.8 7.1 9.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2079 PF09852.9 CDO76578.1 - 0.0013 17.7 2.2 0.0028 16.6 2.2 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) Wzy_C PF04932.15 CDO76578.1 - 0.019 14.6 1.4 0.042 13.5 1.4 1.6 1 0 0 1 1 1 0 O-Antigen ligase HEAT PF02985.22 CDO76578.1 - 0.13 12.6 0.1 0.69 10.3 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat DUF4013 PF13197.6 CDO76578.1 - 0.66 9.8 8.1 0.19 11.6 4.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4013) TssN PF17555.2 CDO76578.1 - 0.88 8.9 5.9 0.61 9.4 4.0 1.6 2 0 0 2 2 2 0 Type VI secretion system, TssN RseC_MucC PF04246.12 CDO76578.1 - 8.3 6.4 5.8 10 6.1 4.1 2.0 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC MFS_1 PF07690.16 CDO76579.1 - 1.4e-39 136.0 46.3 3.2e-39 134.8 45.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 CDO76579.1 - 0.43 10.3 4.2 0.14 11.9 0.2 2.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Trm112p PF03966.16 CDO76580.1 - 3.4e-22 78.8 0.0 4.3e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-ribbon_3 PF13248.6 CDO76580.1 - 0.021 14.2 0.1 0.036 13.5 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-ACC PF17848.1 CDO76580.1 - 0.061 13.4 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-NADH-PPase PF09297.11 CDO76580.1 - 0.066 12.9 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-UDP PF14569.6 CDO76580.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger Methyltransf_30 PF05430.11 CDO76580.1 - 0.19 11.6 0.0 20 5.1 0.0 2.1 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase AhpC-TSA PF00578.21 CDO76581.1 - 4.5e-39 133.2 0.0 6.3e-39 132.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CDO76581.1 - 2e-13 50.0 0.0 3.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CDO76581.1 - 6.1e-13 48.7 0.0 8.7e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin F-box-like PF12937.7 CDO76582.1 - 1.8e-05 24.5 0.1 5.2e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO76582.1 - 0.00021 21.1 0.2 0.00056 19.7 0.2 1.8 1 0 0 1 1 1 1 F-box domain DUF3306 PF11748.8 CDO76582.1 - 0.06 14.2 6.6 0.11 13.4 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) RNase_PH PF01138.21 CDO76584.1 - 9e-19 68.3 0.0 1.3e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDO76584.1 - 3.5e-08 33.3 0.0 5.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Peptidase_M48 PF01435.18 CDO76585.1 - 2.6e-21 76.3 0.4 2.3e-19 69.9 0.4 2.1 1 1 0 1 1 1 1 Peptidase family M48 DEAD PF00270.29 CDO76586.1 - 1.1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AhpC-TSA_2 PF13911.6 CDO76586.1 - 0.0043 17.2 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme ResIII PF04851.15 CDO76586.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Amino_oxidase PF01593.24 CDO76587.1 - 2.4e-50 172.1 0.2 7.7e-48 163.9 0.2 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CDO76587.1 - 2.1e-10 40.7 0.1 8.1e-10 38.8 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDO76587.1 - 8e-07 28.6 0.1 0.00074 18.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDO76587.1 - 0.00037 20.0 1.1 0.00066 19.1 1.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDO76587.1 - 0.00058 19.1 0.2 0.0011 18.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CDO76587.1 - 0.0006 19.2 0.5 0.0006 19.2 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 CDO76587.1 - 0.00073 20.0 0.9 0.06 13.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CDO76587.1 - 0.00076 18.8 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CDO76587.1 - 0.022 14.4 4.7 0.049 13.2 4.7 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CDO76587.1 - 0.035 13.3 0.8 0.069 12.4 0.3 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CDO76587.1 - 0.065 12.3 0.6 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 CDO76587.1 - 0.093 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PIG-P PF08510.12 CDO76588.1 - 0.047 13.6 2.0 0.22 11.5 2.2 2.0 2 0 0 2 2 2 0 PIG-P adh_short PF00106.25 CDO76590.1 - 7.3e-05 22.3 3.0 0.92 8.9 0.0 3.7 3 1 0 3 3 3 3 short chain dehydrogenase Epimerase PF01370.21 CDO76590.1 - 0.033 13.6 2.8 5 6.5 0.0 3.0 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family GMC_oxred_N PF00732.19 CDO76592.1 - 3.7e-53 180.8 0.0 6.5e-52 176.7 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO76592.1 - 7.8e-37 127.0 0.0 1.2e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CDO76592.1 - 1.6e-05 25.1 0.0 3.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDO76592.1 - 0.00065 18.9 0.1 0.012 14.7 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 CDO76592.1 - 0.001 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CDO76592.1 - 0.0021 17.7 0.4 0.0065 16.1 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.18 CDO76592.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 CDO76592.1 - 0.024 13.9 0.1 0.04 13.2 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 CDO76592.1 - 0.093 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Putative_PNPOx PF01243.20 CDO76592.1 - 0.1 12.8 0.0 24 5.2 0.0 2.9 3 0 0 3 3 3 0 Pyridoxamine 5'-phosphate oxidase HI0933_like PF03486.14 CDO76592.1 - 0.29 9.8 0.0 0.53 8.9 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_10 PF13460.6 CDO76593.1 - 4.4e-10 39.8 0.0 7.6e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CDO76593.1 - 1.1e-08 34.9 0.0 7.2e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 CDO76593.1 - 0.039 13.0 0.0 0.086 11.8 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 CDO76593.1 - 0.039 14.2 0.1 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain POC1 PF10450.9 CDO76593.1 - 0.11 11.5 0.0 0.26 10.2 0.0 1.5 2 0 0 2 2 2 0 POC1 chaperone BUD22 PF09073.10 CDO76594.1 - 6.3 6.0 11.9 6.9 5.9 11.9 1.0 1 0 0 1 1 1 0 BUD22 Glyco_hydro_3_C PF01915.22 CDO76595.1 - 3.9e-57 193.5 0.0 6.6e-57 192.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CDO76595.1 - 1.4e-41 143.0 0.0 2.1e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CDO76595.1 - 1.4e-18 66.7 0.1 3e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain p450 PF00067.22 CDO76596.1 - 5.2e-70 236.5 0.0 2.7e-69 234.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 TMEM135_C_rich PF15982.5 CDO76597.1 - 0.22 12.1 11.0 0.048 14.3 6.7 2.1 2 1 1 3 3 3 0 N-terminal cysteine-rich region of Transmembrane protein 135 RseC_MucC PF04246.12 CDO76597.1 - 8.8 6.3 9.6 0.12 12.3 0.8 2.3 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SWIB PF02201.18 CDO76599.1 - 7.4e-23 80.2 0.0 2.3e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain p450 PF00067.22 CDO76601.1 - 7e-58 196.5 0.0 3e-38 131.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 BAR PF03114.18 CDO76602.1 - 8.1e-39 133.7 8.7 1.4e-38 132.9 8.7 1.4 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CDO76602.1 - 2.2e-15 56.0 0.0 4e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDO76602.1 - 2.6e-15 56.0 0.0 5.5e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CDO76602.1 - 6.6e-13 48.1 0.0 1.5e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Filament PF00038.21 CDO76602.1 - 0.0077 15.8 11.6 0.013 15.1 11.6 1.3 1 0 0 1 1 1 1 Intermediate filament protein TMF_TATA_bd PF12325.8 CDO76602.1 - 0.014 15.6 15.5 0.035 14.3 14.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 CDO76602.1 - 0.19 11.8 7.5 0.42 10.7 7.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF932 PF06067.11 CDO76602.1 - 0.2 11.4 2.7 0.38 10.5 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DUF572 PF04502.13 CDO76602.1 - 0.5 9.9 20.0 0.81 9.2 20.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) p450 PF00067.22 CDO76603.1 - 1.3e-14 53.8 0.0 1.4e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hap4_Hap_bind PF10297.9 CDO76605.1 - 6.1e-08 32.5 6.7 1.4e-07 31.4 6.7 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 CDO76605.1 - 0.00075 19.5 20.9 0.0058 16.7 20.9 2.2 1 1 0 1 1 1 1 bZIP transcription factor Phage_Mu_Gam PF07352.12 CDO76605.1 - 0.033 14.1 6.9 0.056 13.4 6.9 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein HAUS-augmin3 PF14932.6 CDO76605.1 - 0.051 13.1 9.2 0.076 12.6 9.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Seadorna_VP6 PF07407.11 CDO76605.1 - 0.059 12.3 1.1 0.084 11.8 1.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein bZIP_2 PF07716.15 CDO76605.1 - 0.18 11.9 18.9 0.46 10.6 5.1 2.7 2 0 0 2 2 2 0 Basic region leucine zipper FAM184 PF15665.5 CDO76605.1 - 0.19 11.5 12.9 0.28 10.9 12.9 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Glutaredoxin2_C PF04399.13 CDO76605.1 - 0.41 10.5 2.5 0.76 9.6 2.5 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain YabA PF06156.13 CDO76605.1 - 0.49 11.1 6.0 0.95 10.1 6.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 CDO76605.1 - 0.58 9.7 6.0 0.88 9.1 6.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Uso1_p115_C PF04871.13 CDO76605.1 - 0.81 10.1 13.5 1.4 9.3 13.5 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Het-C PF07217.11 CDO76605.1 - 3.3 6.1 5.2 4.7 5.6 5.2 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C ZapB PF06005.12 CDO76605.1 - 5.2 7.6 17.5 5.8 7.4 16.3 1.7 1 1 1 2 2 2 0 Cell division protein ZapB NYD-SP28_assoc PF14775.6 CDO76605.1 - 7.7 6.7 7.5 1.5 9.0 1.5 2.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain PPR_2 PF13041.6 CDO76606.1 - 1.3e-25 89.3 0.3 4.7e-07 29.9 0.0 6.7 4 1 2 6 6 6 5 PPR repeat family PPR_3 PF13812.6 CDO76606.1 - 4.5e-25 87.5 0.3 1e-07 31.9 0.0 5.9 4 1 2 6 6 6 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 CDO76606.1 - 1.1e-15 57.0 0.0 4.2e-05 23.1 0.0 4.5 4 0 0 4 4 4 3 PPR repeat PPR PF01535.20 CDO76606.1 - 3e-15 55.3 3.4 5.3e-05 23.2 0.0 6.4 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 CDO76606.1 - 7.5e-10 38.5 6.9 6.2e-06 25.7 0.2 4.0 4 1 0 4 4 4 3 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CDO76606.1 - 0.00022 21.7 6.3 0.7 10.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF3368 PF11848.8 CDO76606.1 - 0.013 15.2 0.2 9.1 6.2 0.0 4.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3368) ATP13 PF12921.7 CDO76606.1 - 0.021 14.7 0.0 6.4 6.7 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ATPase expression TPR_14 PF13428.6 CDO76606.1 - 0.21 12.5 26.0 3.1 8.9 0.1 8.4 9 1 1 10 10 10 0 Tetratricopeptide repeat APH PF01636.23 CDO76607.1 - 7.3e-10 39.2 0.2 1.3e-09 38.3 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDO76607.1 - 0.0022 17.4 0.0 0.0026 17.1 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 CDO76607.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDO76607.1 - 0.075 12.6 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase stn_TNFRSF12A PF12191.8 CDO76610.1 - 0.16 12.2 0.2 0.32 11.2 0.2 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain AMP-binding PF00501.28 CDO76611.1 - 1.9e-27 95.9 0.0 1.9e-26 92.7 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 CDO76611.1 - 0.027 13.4 0.0 0.054 12.4 0.0 1.5 2 0 0 2 2 2 0 GH3 auxin-responsive promoter EamA PF00892.20 CDO76612.1 - 4.1e-11 43.2 25.9 1.1e-07 32.1 3.5 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 CDO76612.1 - 4.2e-05 23.2 11.3 0.00027 20.6 8.2 2.2 2 0 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 CDO76612.1 - 0.00037 19.8 5.8 0.00062 19.1 2.9 2.2 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport DUF3955 PF13127.6 CDO76612.1 - 0.00057 19.6 0.3 0.00057 19.6 0.3 3.1 4 1 0 4 4 4 1 Protein of unknown function (DUF3955) MGTL PF17059.5 CDO76612.1 - 0.098 12.5 1.8 0.32 10.9 1.8 1.9 1 0 0 1 1 1 0 MgtA leader peptide Pho86 PF11124.8 CDO76612.1 - 0.27 10.6 2.6 0.43 10.0 0.9 2.0 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 TPT PF03151.16 CDO76612.1 - 0.96 8.7 11.5 0.14 11.5 1.3 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family SLX9 PF15341.6 CDO76613.1 - 2.5e-21 76.5 2.2 4e-21 75.8 2.2 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 GBP_C PF02841.14 CDO76613.1 - 0.073 12.5 2.1 0.1 12.0 2.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain VPS11_C PF12451.8 CDO76613.1 - 0.13 12.5 0.1 0.4 10.9 0.1 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal DUF4633 PF15464.6 CDO76613.1 - 0.95 9.6 5.8 0.46 10.6 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4633) ZapB PF06005.12 CDO76614.1 - 0.0098 16.3 34.9 0.12 12.8 2.5 5.0 4 1 1 5 5 4 2 Cell division protein ZapB Aminopep PF10023.9 CDO76614.1 - 0.067 12.5 9.0 0.12 11.8 9.0 1.3 1 0 0 1 1 1 0 Putative aminopeptidase Cep57_CLD_2 PF14197.6 CDO76614.1 - 0.15 12.1 20.7 0.026 14.6 8.0 4.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 YabA PF06156.13 CDO76614.1 - 0.19 12.4 18.5 2 9.1 0.1 4.6 3 1 1 4 4 4 0 Initiation control protein YabA GAS PF13851.6 CDO76614.1 - 0.37 10.1 28.9 0.46 9.8 19.5 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPPII_N PF12583.8 CDO76614.1 - 0.49 11.0 5.7 2.6 8.6 5.7 2.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal COG5 PF10392.9 CDO76614.1 - 0.51 10.5 10.9 0.81 9.9 3.7 2.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF4763 PF15960.5 CDO76614.1 - 0.64 9.3 14.0 1.4 8.2 7.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) HAUS-augmin3 PF14932.6 CDO76614.1 - 0.96 9.0 30.1 0.27 10.8 2.9 3.4 3 1 1 4 4 4 0 HAUS augmin-like complex subunit 3 TSC22 PF01166.18 CDO76614.1 - 1.4 9.2 16.7 10 6.5 1.4 4.7 4 0 0 4 4 4 0 TSC-22/dip/bun family FapA PF03961.13 CDO76614.1 - 2.9 6.4 10.1 0.3 9.6 3.7 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A Tho2 PF11262.8 CDO76614.1 - 3 6.9 8.8 8.7 5.4 8.8 1.8 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 HAP1_N PF04849.13 CDO76614.1 - 5.1 6.2 30.8 7.5 5.7 0.0 3.9 3 1 0 3 3 3 0 HAP1 N-terminal conserved region T3SS_TC PF06511.11 CDO76614.1 - 5.6 6.3 11.8 1.3 8.4 7.8 1.9 2 0 0 2 2 2 0 Type III secretion systems tip complex components DASH_Dam1 PF08653.10 CDO76614.1 - 6 6.8 5.4 12 5.8 1.0 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 KASH_CCD PF14662.6 CDO76614.1 - 6.1 6.6 27.4 3.2 7.5 15.9 3.2 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 CDO76614.1 - 6.9 6.4 22.2 9.5 5.9 1.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) CLZ PF16526.5 CDO76614.1 - 7.4 7.0 15.9 0.54 10.6 3.1 3.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tup_N PF08581.10 CDO76614.1 - 7.6 6.9 14.9 0.81 10.0 5.9 3.4 3 2 0 3 3 3 0 Tup N-terminal Rad51 PF08423.11 CDO76615.1 - 1.9e-05 24.1 0.0 0.00012 21.5 0.0 1.9 1 1 0 1 1 1 1 Rad51 AMP-binding PF00501.28 CDO76616.1 - 4.2e-13 48.7 0.6 1.4e-11 43.7 0.6 2.6 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 CDO76616.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 GH3 auxin-responsive promoter PRANC PF09372.10 CDO76617.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 PRANC domain F-box PF00646.33 CDO76617.1 - 0.3 11.0 2.0 0.36 10.8 0.2 2.2 2 0 0 2 2 2 0 F-box domain Nefa_Nip30_N PF10187.9 CDO76619.1 - 1.3e-18 67.3 1.5 1.3e-18 67.3 1.5 2.3 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Es2 PF09751.9 CDO76620.1 - 9.5e-95 318.9 6.9 1.3e-94 318.4 6.9 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 SUZ-C PF12901.7 CDO76620.1 - 0.05 13.6 0.6 0.12 12.4 0.6 1.6 1 0 0 1 1 1 0 SUZ-C motif NUDE_C PF04880.13 CDO76621.1 - 1.9e-11 44.7 7.3 1.9e-11 44.7 7.3 5.9 3 3 4 7 7 3 1 NUDE protein, C-terminal conserved region PRKG1_interact PF15898.5 CDO76621.1 - 0.0026 18.7 28.3 0.0087 16.9 10.0 3.5 1 1 2 3 3 3 2 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 CDO76621.1 - 0.016 15.7 15.4 0.016 15.7 15.4 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 CDO76621.1 - 0.1 11.5 30.1 0.95 8.3 12.3 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 CDO76621.1 - 0.14 11.5 32.9 0.78 9.1 1.1 3.4 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding HIP1_clath_bdg PF16515.5 CDO76621.1 - 0.53 10.9 28.2 4.1 8.1 4.4 3.4 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 CDO76621.1 - 0.75 10.2 27.7 3.1 8.2 13.2 2.4 1 1 1 2 2 2 0 Fez1 ERM PF00769.19 CDO76621.1 - 0.85 9.4 35.6 0.021 14.7 21.8 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family SPATA24 PF15175.6 CDO76621.1 - 1.3 8.9 22.6 0.12 12.2 10.8 2.1 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 DUF3584 PF12128.8 CDO76621.1 - 1.4 6.4 24.8 2 5.8 24.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 CDO76621.1 - 1.5 9.1 29.5 18 5.5 6.6 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF2353 PF09789.9 CDO76621.1 - 1.7 7.9 27.6 0.15 11.4 13.7 2.6 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF3037 PF11236.8 CDO76621.1 - 2.4 8.6 7.3 15 6.1 1.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) TPR_MLP1_2 PF07926.12 CDO76621.1 - 3.5 7.7 36.2 2.5 8.1 11.6 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.11 CDO76621.1 - 6 7.2 22.9 3.4 8.0 0.6 3.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 COG2 PF06148.11 CDO76621.1 - 6.7 6.8 19.1 0.3 11.2 4.2 3.3 2 1 2 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Borrelia_P83 PF05262.11 CDO76621.1 - 8.2 4.8 14.9 12 4.3 14.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein EXOSC1 PF10447.9 CDO76622.1 - 7.4e-18 65.2 1.6 1.2e-12 48.4 0.2 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 2-oxoacid_dh PF00198.23 CDO76623.1 - 7.3e-83 277.6 0.0 9.3e-83 277.2 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CDO76623.1 - 1.2e-19 69.9 0.5 3.2e-19 68.5 0.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CDO76623.1 - 9.8e-16 57.8 0.2 2.4e-15 56.6 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain RNA_pol_Rpc4 PF05132.14 CDO76623.1 - 0.11 12.9 2.1 0.21 12.0 2.1 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 SspB PF04386.13 CDO76623.1 - 2.1 8.2 5.1 43 4.0 3.8 2.3 2 0 0 2 2 2 0 Stringent starvation protein B TMF_TATA_bd PF12325.8 CDO76625.1 - 0.65 10.2 34.8 1.9 8.7 2.8 4.2 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Golgin_A5 PF09787.9 CDO76625.1 - 6.5 6.1 36.6 2.1 7.7 14.6 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 adh_short PF00106.25 CDO76626.1 - 5.5e-33 114.1 0.0 6.7e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO76626.1 - 6.3e-16 58.6 0.0 8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO76626.1 - 8.6e-08 32.3 0.0 3.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 KR domain SP24 PF16504.5 CDO76626.1 - 0.001 19.1 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 Putative virion membrane protein of plant and insect virus Sacchrp_dh_NADP PF03435.18 CDO76626.1 - 0.0016 18.7 0.1 0.0029 17.9 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CDO76626.1 - 0.035 13.6 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CDO76626.1 - 0.061 12.7 0.2 0.079 12.3 0.2 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 CDO76626.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 CDO76627.1 - 8.9e-22 77.5 0.0 9.9e-22 77.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO76627.1 - 1.6e-08 34.4 0.0 1.9e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SP24 PF16504.5 CDO76627.1 - 0.0003 20.8 0.1 0.00052 20.0 0.1 1.3 1 0 0 1 1 1 1 Putative virion membrane protein of plant and insect virus DUF1776 PF08643.10 CDO76627.1 - 0.012 14.9 0.3 0.016 14.6 0.3 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TPR_1 PF00515.28 CDO76628.1 - 3.9e-11 42.3 0.4 0.0015 18.3 0.1 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CDO76628.1 - 7.4e-10 38.2 0.7 0.0047 16.9 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO76628.1 - 0.00021 20.9 0.2 0.1 12.3 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.6 CDO76628.1 - 0.0003 20.6 0.0 0.5 10.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CDO76628.1 - 0.012 15.8 0.1 2.1 8.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDO76628.1 - 0.013 15.8 1.3 4.5 7.6 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDO76628.1 - 0.04 14.8 9.4 0.59 11.1 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDO76628.1 - 0.059 14.0 0.1 0.059 14.0 0.1 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN13_C PF16550.5 CDO76628.1 - 0.085 13.0 0.0 21 5.3 0.0 2.6 2 0 0 2 2 2 0 UCH-binding domain Peptidase_S26 PF10502.9 CDO76629.1 - 2.6e-05 24.0 0.0 0.0018 18.0 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 CDO76629.1 - 0.00026 20.9 0.1 0.00055 19.8 0.1 1.6 1 1 0 1 1 1 1 Peptidase S24-like PAXNEB PF05625.11 CDO76630.1 - 6.8e-60 203.2 0.0 8.8e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein F-box-like PF12937.7 CDO76631.1 - 0.00019 21.2 3.2 0.00073 19.4 3.2 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 CDO76631.1 - 0.12 12.3 0.6 17 5.4 0.0 2.7 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 CDO76631.1 - 0.68 10.4 5.3 9 6.9 0.0 4.4 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) AdoMet_MTase PF07757.13 CDO76632.1 - 9.4e-35 119.3 0.0 3.7e-16 59.4 0.0 2.2 1 1 1 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 CDO76632.1 - 0.0026 17.6 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO76632.1 - 0.02 15.6 0.0 0.059 14.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CDO76632.1 - 0.053 13.3 0.3 0.094 12.5 0.3 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CDO76632.1 - 0.062 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CDO76632.1 - 0.074 13.7 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 CDO76632.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.14 CDO76632.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MTS PF05175.14 CDO76632.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 CDO76632.1 - 0.24 11.4 0.3 0.54 10.2 0.3 1.6 1 1 0 1 1 1 0 Methyltransferase domain Pil1 PF13805.6 CDO76633.1 - 3.9e-49 167.5 1.1 6.8e-49 166.7 1.1 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 CASP_C PF08172.12 CDO76633.1 - 0.01 15.2 2.0 0.6 9.4 1.3 2.3 2 0 0 2 2 2 0 CASP C terminal MCU PF04678.13 CDO76633.1 - 0.16 12.1 1.6 0.28 11.3 1.6 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter YabA PF06156.13 CDO76633.1 - 0.27 11.9 4.9 0.65 10.7 4.3 1.9 2 0 0 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 CDO76633.1 - 5.3 7.6 15.6 5.6 7.5 11.5 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 CDO76633.1 - 6.1 6.7 9.2 3.8 7.4 6.3 2.1 1 1 1 2 2 2 0 Septum formation initiator IF4E PF01652.18 CDO76634.1 - 8.6e-52 175.1 0.0 1.2e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SMN PF06003.12 CDO76637.1 - 1.8e-08 34.0 11.9 1e-07 31.5 12.1 1.7 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 CDO76637.1 - 3e-06 27.3 0.0 5.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Tudor_3 PF18115.1 CDO76637.1 - 0.00083 19.1 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Relaxase PF03432.14 CDO76637.1 - 0.005 16.5 3.2 0.0096 15.6 3.2 1.4 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain Agenet PF05641.12 CDO76637.1 - 0.025 15.0 0.0 0.064 13.7 0.0 1.7 1 0 0 1 1 1 0 Agenet domain Jak1_Phl PF17887.1 CDO76637.1 - 0.32 10.9 7.7 0.087 12.8 3.1 2.1 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain SLC12 PF03522.15 CDO76637.1 - 0.34 9.9 6.2 0.46 9.5 6.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PWWP PF00855.17 CDO76637.1 - 0.4 11.1 9.6 0.24 11.8 5.5 2.6 2 1 0 2 2 2 0 PWWP domain Eapp_C PF10238.9 CDO76637.1 - 0.98 9.5 4.7 1.5 8.9 2.2 2.0 2 0 0 2 2 2 0 E2F-associated phosphoprotein Presenilin PF01080.17 CDO76637.1 - 1.1 8.0 6.8 1.5 7.6 6.8 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CDO76637.1 - 1.5 8.6 13.8 0.45 10.3 8.6 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Rtf2 PF04641.12 CDO76637.1 - 1.8 7.8 13.7 2.9 7.2 8.9 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger NARP1 PF12569.8 CDO76637.1 - 2.2 7.1 12.8 0.15 10.9 7.3 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RIO1 PF01163.22 CDO76638.1 - 3e-48 163.9 0.0 5.5e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CDO76638.1 - 8.9e-34 115.6 0.1 1.7e-33 114.7 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 CDO76638.1 - 4e-11 43.3 0.4 0.00011 22.3 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CDO76638.1 - 2.1e-06 27.2 0.0 6.6e-05 22.4 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YL1 PF05764.13 CDO76638.1 - 0.93 9.6 26.2 1.4 8.9 26.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Acetyltransf_1 PF00583.25 CDO76639.1 - 1e-10 41.9 0.0 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO76639.1 - 6.8e-06 26.4 0.0 8.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDO76639.1 - 1.4e-05 24.9 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CDO76639.1 - 5.6e-05 23.1 0.0 7.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CDO76639.1 - 0.00067 19.2 0.0 0.00078 19.0 0.0 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 CDO76639.1 - 0.0093 16.1 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CDO76639.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pex14_N PF04695.13 CDO76640.1 - 4.4e-22 79.4 4.6 4.4e-22 79.4 4.6 3.6 2 2 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IFT57 PF10498.9 CDO76640.1 - 2e-05 23.7 1.4 3e-05 23.2 1.4 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Mitofilin PF09731.9 CDO76640.1 - 0.0011 18.0 6.9 0.0015 17.4 6.9 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein NUDE_C PF04880.13 CDO76640.1 - 0.0062 17.0 6.2 0.012 16.1 4.7 2.0 1 1 1 2 2 2 1 NUDE protein, C-terminal conserved region ING PF12998.7 CDO76640.1 - 0.0066 17.0 5.5 0.011 16.3 5.0 1.6 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding V_ATPase_I PF01496.19 CDO76640.1 - 0.023 12.6 0.1 0.023 12.6 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1759 PF03564.15 CDO76640.1 - 0.026 14.5 1.0 0.056 13.4 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) Med9 PF07544.13 CDO76640.1 - 0.027 14.6 8.4 0.16 12.0 8.2 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4407 PF14362.6 CDO76640.1 - 0.031 13.7 4.3 0.051 12.9 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 CDO76640.1 - 0.034 12.8 7.8 0.046 12.4 7.8 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.12 CDO76640.1 - 0.037 14.0 10.4 0.071 13.1 10.4 1.4 1 0 0 1 1 1 0 Laminin Domain II MCPsignal PF00015.21 CDO76640.1 - 0.049 13.5 5.2 0.076 12.8 5.2 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.12 CDO76640.1 - 0.083 13.4 12.2 0.53 10.8 0.5 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein CobU PF02283.16 CDO76640.1 - 0.086 12.4 0.7 0.14 11.7 0.7 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF3584 PF12128.8 CDO76640.1 - 0.099 10.1 11.7 0.13 9.7 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prominin PF05478.11 CDO76640.1 - 0.12 10.3 1.7 0.16 9.9 1.7 1.1 1 0 0 1 1 1 0 Prominin DUF334 PF03904.13 CDO76640.1 - 0.17 11.4 3.4 0.23 10.9 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Golgin_A5 PF09787.9 CDO76640.1 - 0.17 11.3 11.4 0.29 10.5 11.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 LMBR1 PF04791.16 CDO76640.1 - 0.21 10.5 0.6 0.26 10.1 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 CDO76640.1 - 0.23 10.6 3.7 0.35 10.1 3.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein RNA_pol_Rpb5_C PF01191.19 CDO76640.1 - 0.26 11.2 1.8 1.2 9.1 0.1 2.3 1 1 1 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Baculo_PEP_C PF04513.12 CDO76640.1 - 0.28 11.2 3.7 0.48 10.5 3.7 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_holin_7_1 PF16081.5 CDO76640.1 - 0.31 11.2 2.6 0.36 11.0 0.4 2.3 3 0 0 3 3 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Spc7 PF08317.11 CDO76640.1 - 0.32 9.8 14.8 0.55 9.1 14.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Noelin-1 PF12308.8 CDO76640.1 - 0.37 10.8 2.6 0.68 10.0 2.6 1.5 1 0 0 1 1 1 0 Neurogenesis glycoprotein APG6_N PF17675.1 CDO76640.1 - 0.37 11.3 14.5 0.93 10.0 14.5 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_32 PF13654.6 CDO76640.1 - 0.47 9.2 7.9 0.67 8.7 7.9 1.1 1 0 0 1 1 1 0 AAA domain Zw10 PF06248.13 CDO76640.1 - 0.51 8.9 6.4 1.1 7.7 6.4 1.5 1 1 0 1 1 1 0 Centromere/kinetochore Zw10 DUF1664 PF07889.12 CDO76640.1 - 0.57 10.2 8.5 2.8 8.0 7.8 2.5 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) DUF4094 PF13334.6 CDO76640.1 - 0.59 10.6 3.7 0.97 9.9 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Pil1 PF13805.6 CDO76640.1 - 0.66 9.4 11.3 0.08 12.4 7.1 1.6 2 0 0 2 2 1 0 Eisosome component PIL1 DUF5094 PF17015.5 CDO76640.1 - 1 9.4 5.0 1.5 8.9 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) BshC PF10079.9 CDO76640.1 - 1.1 7.9 8.1 1.7 7.3 1.4 1.7 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC CorA PF01544.18 CDO76640.1 - 1.3 8.3 3.6 2.3 7.5 3.6 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF812 PF05667.11 CDO76640.1 - 1.5 7.6 12.5 2.3 7.0 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fez1 PF06818.15 CDO76640.1 - 1.6 9.2 10.4 2.5 8.5 10.4 1.2 1 0 0 1 1 1 0 Fez1 FlgN PF05130.12 CDO76640.1 - 1.8 9.0 14.3 0.91 10.0 12.1 1.6 2 0 0 2 2 1 0 FlgN protein DLP_helical PF18709.1 CDO76640.1 - 2.1 7.5 8.9 4.5 6.4 8.8 1.6 1 1 0 1 1 1 0 Dynamin-like helical domain Sas10_Utp3 PF04000.15 CDO76640.1 - 2.1 9.0 5.5 9.1 7.0 1.5 2.5 2 0 0 2 2 2 0 Sas10/Utp3/C1D family YkuI_C PF10388.9 CDO76640.1 - 2.3 8.0 4.6 17 5.2 0.0 2.7 2 1 1 3 3 3 0 EAL-domain associated signalling protein domain DUF3450 PF11932.8 CDO76640.1 - 2.5 7.4 13.5 3.7 6.8 11.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) AcylCoA_dehyd_C PF12186.8 CDO76640.1 - 2.8 8.1 6.3 3.9 7.6 1.0 2.3 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal Fib_alpha PF08702.10 CDO76640.1 - 4 7.6 6.2 8 6.6 6.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Mt_ATP-synt_D PF05873.12 CDO76640.1 - 4.7 7.0 11.3 4 7.3 1.3 2.3 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) COG2 PF06148.11 CDO76640.1 - 4.8 7.3 12.7 10 6.2 5.9 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_Mu_Gam PF07352.12 CDO76640.1 - 9 6.2 13.6 3.9 7.4 3.3 2.9 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein GTP_EFTU PF00009.27 CDO76641.1 - 2e-57 193.9 0.4 5.8e-57 192.4 0.5 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CDO76641.1 - 8e-27 93.8 0.4 1.7e-26 92.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CDO76641.1 - 1.3e-16 60.7 3.2 3.4e-16 59.4 3.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CDO76641.1 - 0.00012 22.1 0.1 0.00022 21.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CDO76641.1 - 0.0027 17.6 0.1 0.0066 16.4 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 CDO76641.1 - 0.01 15.6 0.3 4.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CDO76641.1 - 0.01 15.4 1.0 0.017 14.7 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GCV_H PF01597.19 CDO76642.1 - 1.7e-43 147.4 0.9 2.1e-43 147.1 0.9 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 CDO76642.1 - 5.3e-05 23.1 0.3 0.00015 21.6 0.1 1.8 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 CDO76642.1 - 6e-05 22.8 0.1 0.00012 21.8 0.1 1.5 2 0 0 2 2 2 1 Biotin-requiring enzyme RNaseH_C PF09293.10 CDO76642.1 - 0.061 13.7 0.2 2 8.8 0.2 2.3 1 1 0 1 1 1 0 T4 RNase H, C terminal Peptidase_M23 PF01551.22 CDO76642.1 - 0.19 12.0 0.6 3.4 7.9 0.4 2.3 1 1 1 2 2 2 0 Peptidase family M23 ESSS PF10183.9 CDO76643.1 - 1.3e-12 47.9 0.0 1.4e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GRIP PF01465.20 CDO76644.1 - 2.5e-07 30.5 0.0 6.1e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 GRIP domain DUF4201 PF13870.6 CDO76644.1 - 0.00013 21.8 13.9 0.00013 21.8 13.9 5.3 2 1 2 5 5 5 2 Domain of unknown function (DUF4201) Pox_A_type_inc PF04508.12 CDO76644.1 - 0.25 11.3 4.1 0.2 11.6 0.4 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Spc7 PF08317.11 CDO76644.1 - 1.1 8.1 88.8 0.0035 16.3 17.0 4.7 1 1 4 5 5 5 0 Spc7 kinetochore protein Cation_efflux PF01545.21 CDO76645.1 - 5.3e-46 156.9 10.1 1.3e-28 100.1 3.6 2.1 2 0 0 2 2 2 2 Cation efflux family MASE4 PF17158.4 CDO76645.1 - 0.0075 15.6 1.6 0.0075 15.6 1.6 1.6 1 1 0 1 1 1 1 Membrane-associated sensor, integral membrane domain Pilus_CpaD PF09476.10 CDO76645.1 - 0.029 14.1 1.3 0.7 9.6 0.0 2.1 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) ZT_dimer PF16916.5 CDO76645.1 - 0.066 13.3 0.4 0.14 12.3 0.4 1.5 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Retrotran_gag_2 PF14223.6 CDO76648.1 - 1.6e-11 44.0 0.1 3.2e-10 39.8 0.0 2.1 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO76648.1 - 0.075 12.9 0.2 0.24 11.3 0.2 1.9 1 0 0 1 1 1 0 GAG-pre-integrase domain DUF4219 PF13961.6 CDO76648.1 - 0.11 12.2 2.9 6.4 6.6 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) MIR PF02815.19 CDO76649.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.3 1 1 0 1 1 1 0 MIR domain SAM_Exu PF18609.1 CDO76649.1 - 0.12 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Exuperantia SAM-like domain Plavaka PF18759.1 CDO76650.1 - 1.2e-54 185.7 0.8 1.5e-54 185.4 0.8 1.1 1 0 0 1 1 1 1 Plavaka transposase GMC_oxred_C PF05199.13 CDO76651.1 - 2.7e-16 60.4 0.1 3.1e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase PgaPase_1 PF06162.12 CDO76651.1 - 0.048 13.4 0.0 0.06 13.1 0.0 1.0 1 0 0 1 1 1 0 Putative pyroglutamyl peptidase PgaPase_1 GMC_oxred_N PF00732.19 CDO76652.1 - 6.7e-49 166.8 0.0 3e-27 95.8 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO76652.1 - 1.8e-31 109.6 0.0 2.8e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 CDO76652.1 - 0.01 15.1 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 CDO76652.1 - 0.013 15.8 0.1 0.037 14.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDO76652.1 - 0.017 14.2 0.1 0.056 12.5 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 CDO76652.1 - 0.031 13.3 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CDO76652.1 - 0.035 13.4 0.2 0.16 11.2 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CDO76652.1 - 0.044 13.4 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 CDO76653.1 - 8.1e-41 140.3 0.0 1.8e-40 139.1 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO76653.1 - 5.9e-33 114.4 0.0 9.8e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Senescence PF06911.12 CDO76654.1 - 6.5e-14 52.7 14.2 1.3e-13 51.7 14.2 1.5 1 0 0 1 1 1 1 Senescence-associated protein Oleosin PF01277.17 CDO76654.1 - 0.18 11.5 1.0 0.43 10.3 1.0 1.6 1 0 0 1 1 1 0 Oleosin DDE_3 PF13358.6 CDO76658.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease UQ_con PF00179.26 CDO76659.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme peroxidase PF00141.23 CDO76660.1 - 3e-46 157.9 0.0 4.7e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ESSS PF10183.9 CDO76660.1 - 0.096 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Arrestin_C PF02752.22 CDO76661.1 - 3.7e-13 50.1 0.0 2.9e-08 34.2 0.1 3.2 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CDO76661.1 - 2.7e-08 34.0 0.0 1.1e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CDO76661.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like Pol_alpha_B_N PF08418.10 CDO76661.1 - 0.061 13.3 2.4 0.11 12.5 2.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DDE_Tnp_4 PF13359.6 CDO76663.1 - 3.6e-14 52.7 0.0 6.6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease KcnmB2_inactiv PF09303.10 CDO76663.1 - 0.29 11.0 1.3 11 5.9 0.0 2.5 2 0 0 2 2 2 0 KCNMB2, ball and chain domain F-box-like PF12937.7 CDO76664.1 - 0.00017 21.4 0.8 0.00038 20.3 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO76664.1 - 0.00046 20.0 0.9 0.0017 18.2 0.9 2.0 1 0 0 1 1 1 1 F-box domain Methyltransf_22 PF13383.6 CDO76665.1 - 3.1e-05 23.7 0.6 0.003 17.2 0.2 2.6 2 1 1 3 3 3 2 Methyltransferase domain TLD PF07534.16 CDO76666.1 - 1.4e-34 119.3 0.0 2.4e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 TLD CCSAP PF15748.5 CDO76666.1 - 1.3 9.2 5.9 0.92 9.6 4.4 1.5 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated HSP20 PF00011.21 CDO76667.1 - 3.2e-26 91.4 0.6 4e-26 91.1 0.6 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CDO76667.1 - 6e-11 41.7 0.0 9.7e-11 41.1 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 CDO76667.1 - 0.023 15.7 0.1 0.062 14.3 0.1 1.6 1 1 1 2 2 2 0 CS domain FKBP26_C PF18046.1 CDO76667.1 - 0.045 13.9 0.2 7 6.8 0.1 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal BON PF04972.17 CDO76667.1 - 0.071 13.4 0.1 0.88 9.9 0.1 2.1 2 0 0 2 2 2 0 BON domain HMA PF00403.26 CDO76667.1 - 0.1 13.1 0.2 10 6.7 0.2 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain ubiquitin PF00240.23 CDO76668.1 - 0.084 12.6 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family Roughex PF06020.11 CDO76668.1 - 0.16 11.0 0.9 0.29 10.2 0.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ntox34 PF15606.6 CDO76668.1 - 0.19 11.9 1.1 0.44 10.7 0.3 2.1 2 0 0 2 2 2 0 Bacterial toxin 34 Roughex PF06020.11 CDO76669.1 - 0.096 11.8 1.6 0.16 11.0 1.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ntox34 PF15606.6 CDO76669.1 - 0.21 11.7 1.1 0.5 10.5 0.3 2.0 2 0 0 2 2 2 0 Bacterial toxin 34 BTB PF00651.31 CDO76671.1 - 1.2e-12 48.1 0.1 1.6e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain PSD5 PF07637.11 CDO76671.1 - 0.043 14.2 0.6 0.13 12.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) adh_short_C2 PF13561.6 CDO76672.1 - 8.2e-38 130.3 0.1 2.3e-36 125.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO76672.1 - 1.2e-26 93.4 0.5 2.5e-24 85.8 0.5 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO76672.1 - 0.00046 20.1 0.3 0.0016 18.3 0.1 1.8 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.6 CDO76673.1 - 6e-37 127.4 0.1 2e-33 115.9 0.0 2.1 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO76673.1 - 4.8e-26 91.4 0.1 1.5e-16 60.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO76674.1 - 2.2e-55 187.8 0.0 2.7e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CDO76674.1 - 2.9e-40 137.8 0.1 3.7e-40 137.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CDO76674.1 - 2.1e-11 44.0 0.2 3.1e-11 43.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Thymidylat_synt PF00303.19 CDO76675.1 - 1e-108 362.6 0.0 1.1e-108 362.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase RNA_pol_inhib PF16857.5 CDO76676.1 - 0.16 11.8 2.6 0.28 11.0 0.5 2.5 2 0 0 2 2 2 0 RNA polymerase inhibitor TPR_12 PF13424.6 CDO76676.1 - 0.74 10.1 30.1 0.69 10.3 4.2 6.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDO76676.1 - 8.4 6.9 12.7 58 4.3 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Peptidase_C50 PF03568.17 CDO76677.1 - 1.2e-141 472.5 0.0 1.4e-141 472.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 CDO76677.1 - 0.00084 18.8 0.0 0.2 11.0 0.0 2.3 1 1 0 2 2 2 2 CHAT domain G-alpha PF00503.20 CDO76678.1 - 2.1e-102 342.9 0.0 2.7e-102 342.5 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDO76678.1 - 2.7e-10 40.0 0.0 4.3e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CDO76678.1 - 0.0023 18.1 0.0 3.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CDO76678.1 - 0.0038 16.9 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CDO76678.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family GPP34 PF05719.11 CDO76679.1 - 5e-56 190.0 2.7 6.5e-56 189.6 2.7 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Chs7 PF12271.8 CDO76680.1 - 2.3e-77 260.2 8.1 4e-51 174.1 0.2 2.0 1 1 1 2 2 2 2 Chitin synthase export chaperone FAD_binding_3 PF01494.19 CDO76682.1 - 3.8e-12 46.1 0.1 1e-11 44.7 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CDO76682.1 - 3.3e-08 33.1 0.0 0.00031 20.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CDO76682.1 - 5.6e-08 32.5 0.5 0.011 15.0 0.0 2.9 3 1 0 4 4 4 2 Flavin containing amine oxidoreductase DAO PF01266.24 CDO76682.1 - 9.5e-08 32.0 2.1 0.0017 18.0 0.6 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 CDO76682.1 - 1.6e-06 28.6 0.0 0.00036 21.0 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO76682.1 - 0.00022 21.4 0.4 0.00053 20.2 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CDO76682.1 - 0.00037 19.3 0.1 0.0015 17.3 0.1 1.8 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 CDO76682.1 - 0.00089 18.2 0.0 0.12 11.2 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 CDO76682.1 - 0.0011 18.2 0.6 0.0046 16.1 0.1 2.2 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 CDO76682.1 - 0.0021 17.2 0.1 0.061 12.4 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CDO76682.1 - 0.014 14.6 0.0 0.046 13.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CDO76682.1 - 0.02 14.3 0.3 0.038 13.3 0.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CDO76682.1 - 0.037 13.3 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CDO76682.1 - 0.058 12.5 0.6 0.1 11.7 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Con-6 PF10346.9 CDO76683.1 - 1.4e-36 124.2 14.2 3.2e-15 55.9 1.4 3.3 3 0 0 3 3 3 3 Conidiation protein 6 SpoIIIAH PF12685.7 CDO76683.1 - 0.001 19.0 0.5 0.042 13.7 0.1 2.3 2 0 0 2 2 2 2 SpoIIIAH-like protein ATP-synt_DE PF00401.20 CDO76683.1 - 0.017 15.4 9.3 0.056 13.7 0.7 3.7 4 0 0 4 4 4 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Con-6 PF10346.9 CDO76684.1 - 1.3e-46 156.3 12.9 3.6e-15 55.7 0.6 3.5 3 0 0 3 3 3 3 Conidiation protein 6 FmdA_AmdA PF03069.15 CDO76684.1 - 9.1e-38 130.1 0.0 1.8e-22 79.7 0.0 3.3 2 1 1 3 3 3 3 Acetamidase/Formamidase family Peptidase_M22 PF00814.25 CDO76685.1 - 1.1e-42 146.6 0.0 1.3e-42 146.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Peptidase_C2 PF00648.21 CDO76685.1 - 0.2 10.6 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Calpain family cysteine protease XPG_I PF00867.18 CDO76686.1 - 4.9e-06 26.8 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 CDO76686.1 - 0.0076 17.1 27.7 0.056 14.3 16.2 4.4 3 1 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain Cwf_Cwc_15 PF04889.12 CDO76686.1 - 0.48 10.1 19.0 0.059 13.1 7.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Amidohydro_3 PF07969.11 CDO76687.1 - 4.1e-88 296.9 0.6 5.1e-88 296.6 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CDO76687.1 - 1.2e-13 51.1 0.0 5.7e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family zf-rbx1 PF12678.7 CDO76688.1 - 5.9e-13 48.9 3.8 1e-12 48.1 3.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CDO76688.1 - 3.7e-10 40.0 6.5 1e-09 38.6 2.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CDO76688.1 - 1.3e-07 31.4 2.4 2.6e-07 30.4 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO76688.1 - 2.7e-07 30.5 1.6 5.4e-07 29.5 1.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CDO76688.1 - 5.3e-06 26.2 4.8 5.3e-06 26.2 4.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CDO76688.1 - 5.4e-05 23.0 6.1 0.00053 19.8 1.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDO76688.1 - 0.00014 21.6 2.6 0.00016 21.5 0.6 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CDO76688.1 - 0.00048 19.8 4.1 0.00093 18.9 0.5 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CDO76688.1 - 0.00051 20.0 3.1 0.0015 18.6 3.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CDO76688.1 - 0.00059 19.4 0.6 0.00059 19.4 0.6 1.5 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CDO76688.1 - 0.0016 18.3 5.9 0.0076 16.2 6.1 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CDO76688.1 - 0.0046 17.1 1.9 0.01 16.0 1.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CDO76688.1 - 0.052 13.7 0.3 0.13 12.5 0.3 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 CDO76688.1 - 0.6 10.5 2.8 1.1 9.6 2.8 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 CDO76688.1 - 1.7 8.5 4.0 1.1 9.2 1.2 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YqeY PF09424.10 CDO76689.1 - 2e-22 79.8 0.2 2.2e-22 79.7 0.2 1.0 1 0 0 1 1 1 1 Yqey-like protein Pkinase_fungal PF17667.1 CDO76690.1 - 8.4e-44 150.0 0.0 2.8e-32 112.0 0.0 2.3 3 0 0 3 3 3 2 Fungal protein kinase polyprenyl_synt PF00348.17 CDO76691.1 - 1.1e-42 145.9 0.0 1.3e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DEAD PF00270.29 CDO76692.1 - 2.3e-13 50.3 0.0 4.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO76692.1 - 6.4e-12 45.8 0.0 1.7e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCHC_6 PF15288.6 CDO76692.1 - 3e-06 26.9 1.0 7.3e-06 25.7 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle DLH PF01738.18 CDO76693.1 - 3.7e-24 85.5 0.0 9.2e-24 84.2 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CDO76693.1 - 0.0066 16.1 0.0 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold EI24 PF07264.11 CDO76694.1 - 3e-07 30.9 0.3 5.1e-07 30.1 0.3 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Cofilin_ADF PF00241.20 CDO76695.1 - 9.5e-42 141.6 0.3 1.1e-41 141.4 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CH PF00307.31 CDO76696.1 - 6e-34 116.5 0.5 1.5e-16 60.5 0.0 3.4 2 1 1 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 CDO76696.1 - 2.9e-17 62.5 0.1 2.1e-16 59.8 0.0 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 CDO76696.1 - 8e-10 38.4 0.2 3.3e-06 26.8 0.2 2.6 2 0 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.21 CDO76696.1 - 0.00034 21.1 1.5 0.18 12.3 0.3 3.1 2 1 0 2 2 2 1 Spectrin repeat EF-hand_6 PF13405.6 CDO76696.1 - 0.00082 19.1 0.0 0.0042 16.9 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CDO76696.1 - 0.0092 15.5 0.0 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 EF hand TetR_C_24 PF17932.1 CDO76696.1 - 0.045 14.0 3.4 14 6.0 0.2 3.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L36e PF01158.18 CDO76696.1 - 0.079 13.2 0.2 0.18 12.1 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein L36e MutS_II PF05188.17 CDO76696.1 - 0.11 12.8 0.1 0.55 10.5 0.0 2.2 1 1 0 1 1 1 0 MutS domain II EF-hand_8 PF13833.6 CDO76696.1 - 0.11 12.3 0.2 4.3 7.3 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.6 CDO76696.1 - 0.12 12.8 0.8 0.57 10.7 0.2 2.5 2 0 0 2 2 2 0 EF-hand domain pair DUF4061 PF13270.6 CDO76696.1 - 0.13 12.6 2.1 1.2 9.5 0.6 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) EF-hand_14 PF17959.1 CDO76696.1 - 0.15 12.5 0.9 13 6.2 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain LUC7 PF03194.15 CDO76696.1 - 0.38 10.4 5.0 0.13 12.0 1.4 1.8 2 0 0 2 2 2 0 LUC7 N_terminus ApoLp-III PF07464.11 CDO76696.1 - 0.49 10.5 2.4 7.7 6.6 0.0 2.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) FAM184 PF15665.5 CDO76696.1 - 0.5 10.1 11.3 0.95 9.2 1.0 2.6 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B CENP-F_leu_zip PF10473.9 CDO76696.1 - 0.9 9.6 8.7 0.038 14.0 2.8 1.8 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4456 PF14644.6 CDO76696.1 - 1.5 8.4 8.0 0.33 10.6 3.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4456) Fib_alpha PF08702.10 CDO76696.1 - 2.1 8.6 6.2 6 7.1 0.5 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family POB3_N PF17292.2 CDO76697.1 - 1.9e-28 98.7 0.1 8.8e-24 83.8 0.0 2.7 2 1 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 CDO76697.1 - 1.5e-27 95.3 0.0 5.4e-27 93.5 0.0 2.1 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 CDO76697.1 - 1.1e-21 77.0 0.0 2.6e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DLH PF01738.18 CDO76700.1 - 9.6e-27 93.9 0.0 3e-26 92.3 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CDO76700.1 - 0.027 14.1 0.0 0.056 13.1 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.25 CDO76701.1 - 2.8e-46 158.0 0.0 4.5e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76701.1 - 2.4e-23 82.7 0.0 5.5e-23 81.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO76701.1 - 0.0002 21.4 0.0 0.00067 19.7 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDO76701.1 - 0.00042 19.7 0.0 0.00093 18.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CDO76701.1 - 0.038 13.6 0.0 0.038 13.6 0.0 2.2 3 0 0 3 3 3 0 RIO1 family TPR_MLP1_2 PF07926.12 CDO76702.1 - 4.4e-29 101.2 27.0 4.4e-29 101.2 27.0 19.1 8 5 10 19 19 19 9 TPR/MLP1/MLP2-like protein Mob1_phocein PF03637.17 CDO76703.1 - 9.8e-68 227.4 0.9 1.2e-67 227.1 0.9 1.1 1 0 0 1 1 1 1 Mob1/phocein family DHR10 PF18595.1 CDO76706.1 - 0.0095 16.0 1.8 0.017 15.2 1.8 1.3 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain Aldo_ket_red PF00248.21 CDO76707.1 - 3e-41 141.5 0.0 3.5e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S13 PF00416.22 CDO76708.1 - 1.1e-54 184.2 2.2 1.3e-54 184.0 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CDO76708.1 - 0.0056 15.5 0.0 0.0059 15.4 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 CDO76708.1 - 0.008 16.4 0.2 0.029 14.6 0.1 1.9 2 1 0 2 2 2 1 Helix-hairpin-helix motif DUF2746 PF10874.8 CDO76708.1 - 0.035 14.5 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) DUF3196 PF11428.8 CDO76708.1 - 0.13 11.8 0.0 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3196) CBFB_NFYA PF02045.15 CDO76710.1 - 4.8e-28 97.6 6.9 4.8e-28 97.6 6.9 2.2 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Lin-8 PF03353.15 CDO76710.1 - 1.9 8.0 9.4 2.6 7.5 9.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1387 PF07139.11 CDO76710.1 - 6.1 6.5 9.0 9.8 5.8 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) TFIIA PF03153.13 CDO76711.1 - 1 9.3 8.3 1 9.3 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HeH PF12949.7 CDO76712.1 - 6.5e-07 28.9 1.3 1.3e-06 28.0 1.3 1.4 1 0 0 1 1 1 1 HeH/LEM domain Tho1_MOS11_C PF18592.1 CDO76712.1 - 1e-05 25.2 0.2 1.7 8.5 0.0 3.3 3 0 0 3 3 3 2 Tho1/MOS11 C-terminal domain Rho_N PF07498.12 CDO76712.1 - 0.00023 21.0 0.5 0.00047 20.0 0.5 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.27 CDO76712.1 - 0.093 12.5 0.6 0.72 9.7 0.6 2.2 1 1 0 1 1 1 0 SAP domain Gemini_C4 PF01492.17 CDO76712.1 - 0.16 11.9 2.8 3.1 7.8 0.0 2.7 2 0 0 2 2 2 0 Geminivirus C4 protein Apt1 PF10351.9 CDO76712.1 - 0.26 10.1 7.3 0.28 10.0 7.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CDO76712.1 - 1.4 7.6 6.1 1.5 7.5 6.1 1.2 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.12 CDO76712.1 - 1.4 7.5 12.7 1.4 7.5 12.7 1.2 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 CDO76712.1 - 1.9 8.4 13.0 2.4 8.0 13.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 CDO76712.1 - 1.9 6.9 6.6 2.3 6.7 6.6 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 CDO76712.1 - 4.5 6.7 5.8 5.4 6.5 5.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SOG2 PF10428.9 CDO76712.1 - 5.3 6.1 16.1 6 6.0 16.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FAM70 PF14967.6 CDO76712.1 - 7.6 5.9 10.3 10 5.5 10.3 1.2 1 0 0 1 1 1 0 FAM70 protein PRY PF13765.6 CDO76713.1 - 0.25 11.0 1.0 6.9 6.4 0.1 2.5 2 0 0 2 2 2 0 SPRY-associated domain HET PF06985.11 CDO76714.1 - 1.7e-10 41.4 7.0 3.8e-08 33.8 2.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-C2H2_2 PF12756.7 CDO76715.1 - 3.5e-36 123.6 12.4 4.8e-31 107.1 0.1 3.3 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CDO76715.1 - 8.7e-08 32.3 1.1 8.7e-08 32.3 1.1 2.1 2 0 0 2 2 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CDO76715.1 - 1.6e-07 31.5 1.1 1.6e-07 31.5 1.1 3.5 4 1 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CDO76715.1 - 0.00021 21.9 14.1 0.012 16.4 0.1 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger Pox_Ag35 PF03286.14 CDO76715.1 - 0.0019 18.0 10.8 0.0019 18.0 10.8 2.4 3 0 0 3 3 3 1 Pox virus Ag35 surface protein zf-C2H2 PF00096.26 CDO76715.1 - 0.022 15.2 0.5 0.022 15.2 0.5 4.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CDO76715.1 - 0.055 13.5 0.8 0.055 13.5 0.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-UBP_var PF17807.1 CDO76715.1 - 0.061 13.1 0.5 1.3 8.8 0.2 2.6 2 0 0 2 2 2 0 Variant UBP zinc finger zf-DBF PF07535.12 CDO76715.1 - 1.3 9.2 8.0 0.32 11.1 0.4 2.8 2 0 0 2 2 2 0 DBF zinc finger BUD22 PF09073.10 CDO76715.1 - 1.7 7.9 22.2 0.29 10.4 14.3 2.1 2 0 0 2 2 2 0 BUD22 DUF3449 PF11931.8 CDO76715.1 - 3.6 7.3 17.2 0.65 9.8 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) CDC45 PF02724.14 CDO76715.1 - 3.8 5.7 8.6 5.5 5.2 8.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Rax2 PF12768.7 CDO76716.1 - 6.6e-47 159.7 7.9 1.6e-44 152.0 0.4 5.2 6 0 0 6 6 6 2 Cortical protein marker for cell polarity Kelch_6 PF13964.6 CDO76716.1 - 0.00013 22.1 6.4 0.11 12.8 0.1 6.0 6 0 0 6 6 6 1 Kelch motif SH3_1 PF00018.28 CDO76716.1 - 0.003 17.1 0.1 0.0061 16.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain Kelch_3 PF13415.6 CDO76716.1 - 0.0088 16.3 3.1 23 5.4 0.0 5.1 4 0 0 4 4 4 2 Galactose oxidase, central domain PQQ_3 PF13570.6 CDO76716.1 - 4.9 7.8 12.4 1.3 9.6 0.4 4.6 4 0 0 4 4 4 0 PQQ-like domain Dioxygenase_C PF00775.21 CDO76717.1 - 3.8e-43 147.0 0.0 5.3e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 CDO76717.1 - 2.6e-27 94.5 0.0 4e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus DUF1279 PF06916.13 CDO76718.1 - 1.3e-18 67.3 0.0 1.8e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) SecY PF00344.20 CDO76718.1 - 0.18 11.1 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 SecY translocase SAM_decarbox PF01536.16 CDO76719.1 - 2.8e-96 322.6 0.0 6e-96 321.5 0.0 1.5 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase PP2C PF00481.21 CDO76720.1 - 4.9e-22 78.8 0.0 2e-21 76.8 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CDO76720.1 - 5.9e-07 29.3 0.0 1.5e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3131 PF11329.8 CDO76721.1 - 0.084 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) Dfp1_Him1_M PF08630.10 CDO76723.1 - 1.9e-35 121.8 1.6 2.2e-35 121.7 0.0 1.9 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 CDO76723.1 - 3.3e-21 75.1 0.8 7e-21 74.1 0.8 1.6 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 CDO76723.1 - 0.095 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain zf-C2H2_9 PF16293.5 CDO76723.1 - 0.17 11.7 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) BRCT PF00533.26 CDO76723.1 - 0.17 12.2 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain GCP_C_terminal PF04130.13 CDO76725.1 - 2.4e-37 129.1 0.0 1.5e-29 103.5 0.0 2.4 2 0 0 2 2 2 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CDO76725.1 - 4.8e-07 29.7 0.0 1.3e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal AAA_22 PF13401.6 CDO76726.1 - 1.1e-11 45.1 0.0 2.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CDO76726.1 - 2.2e-09 37.8 0.0 5.2e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CDO76726.1 - 3.7e-09 37.2 0.0 1.7e-08 35.1 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 CDO76726.1 - 0.00022 20.6 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CDO76726.1 - 0.00023 21.1 0.0 0.00051 20.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TniB PF05621.11 CDO76726.1 - 0.00049 19.6 0.0 0.00082 18.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_5 PF07728.14 CDO76726.1 - 0.0066 16.4 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CDO76726.1 - 0.0069 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CDO76726.1 - 0.0093 15.7 0.1 0.03 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CDO76726.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 CDO76726.1 - 0.043 13.1 0.3 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 CDO76726.1 - 0.05 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 CDO76726.1 - 0.061 13.2 0.1 0.21 11.5 0.1 1.8 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 CDO76726.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 CDO76726.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 CDO76726.1 - 0.11 12.9 0.0 0.41 11.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase cobW PF02492.19 CDO76726.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 CDO76726.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CDO76726.1 - 0.15 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CDO76726.1 - 0.22 11.7 1.0 0.39 10.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain BTB PF00651.31 CDO76729.1 - 0.096 12.9 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain Oberon_cc PF16312.5 CDO76730.1 - 0.31 11.0 7.6 0.081 12.9 4.2 1.7 2 0 0 2 2 2 0 Coiled-coil region of Oberon DUF1174 PF06671.11 CDO76733.1 - 0.16 11.7 0.2 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1174) Lactonase PF10282.9 CDO76735.1 - 6.7e-49 167.0 0.0 7.7e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DHQS PF01959.16 CDO76735.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 3-dehydroquinate synthase II p450 PF00067.22 CDO76737.1 - 7.4e-63 212.9 0.1 1.3e-59 202.2 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 E1-E2_ATPase PF00122.20 CDO76739.1 - 1.2e-48 165.0 0.2 1.2e-48 165.0 0.2 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDO76739.1 - 3.6e-37 127.8 0.5 3.6e-37 127.8 0.5 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDO76739.1 - 4.9e-17 62.9 1.5 3.4e-13 50.4 0.5 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CDO76739.1 - 1.1e-12 47.4 0.0 3e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CDO76739.1 - 1.1e-11 44.6 0.0 9.2e-11 41.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CDO76739.1 - 2.3e-05 24.3 1.4 0.0019 18.0 0.8 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 CDO76739.1 - 0.0048 16.8 2.3 0.0058 16.6 0.0 2.3 3 0 0 3 3 3 1 Positive regulator of sigma(E), RseC/MucC HAD PF12710.7 CDO76739.1 - 0.0078 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1275 PF06912.11 CDO76739.1 - 7.6 6.4 18.7 2.7 7.9 0.2 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1275) RVT_1 PF00078.27 CDO76740.1 - 9.4e-42 143.0 0.0 1.8e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO76740.1 - 2.4e-18 66.7 0.1 6e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO76740.1 - 7.6e-06 26.6 1.4 3.1e-05 24.6 1.4 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CDO76740.1 - 0.059 12.9 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.6 CDO76740.1 - 0.79 9.7 2.8 1.7 8.7 2.8 1.4 1 0 0 1 1 1 0 FlxA-like protein AAT PF03417.16 CDO76742.1 - 5.5e-17 62.2 0.0 8.8e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase CoA_transf_3 PF02515.17 CDO76743.1 - 3.2e-96 322.7 0.0 3.9e-96 322.4 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III RhoGEF PF00621.20 CDO76744.1 - 9.2e-34 117.3 0.0 2.1e-33 116.1 0.0 1.6 2 0 0 2 2 2 1 RhoGEF domain DUF2130 PF09903.9 CDO76744.1 - 0.096 11.9 0.2 0.15 11.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) FAD_binding_4 PF01565.23 CDO76745.1 - 5.4e-06 26.2 0.0 0.00054 19.7 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain Aldo_ket_red PF00248.21 CDO76747.1 - 9.4e-53 179.3 0.0 3.1e-52 177.6 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Spindle_Spc25 PF08234.12 CDO76747.1 - 0.058 13.6 0.1 11 6.3 0.1 3.0 3 0 0 3 3 3 0 Chromosome segregation protein Spc25 DUF2744 PF10910.8 CDO76747.1 - 0.066 13.2 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2744) Efg1 PF10153.9 CDO76748.1 - 9.8e-38 129.0 6.7 9.8e-38 129.0 6.7 2.4 3 0 0 3 3 3 1 rRNA-processing protein Efg1 KI67R PF08065.12 CDO76748.1 - 0.12 12.9 0.1 0.12 12.9 0.1 3.1 3 1 0 3 3 3 0 KI67R (NUC007) repeat TFIIA PF03153.13 CDO76748.1 - 1.2 9.0 17.5 2 8.3 17.5 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDE_3 PF13358.6 CDO76750.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF5398 PF17376.2 CDO76751.1 - 0.033 14.8 0.0 0.055 14.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5398) U-box PF04564.15 CDO76751.1 - 0.071 13.3 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 U-box domain DAHP_synth_1 PF00793.20 CDO76752.1 - 4.5e-57 193.0 0.0 6.1e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Voldacs PF03517.13 CDO76753.1 - 0.28 11.3 2.1 0.92 9.6 0.7 2.0 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling PIH1 PF08190.12 CDO76754.1 - 0.0058 16.1 0.0 4.6 6.7 0.0 3.0 3 0 0 3 3 3 2 PIH1 N-terminal domain PRCC PF10253.9 CDO76754.1 - 0.054 14.3 4.9 0.077 13.8 4.9 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Hamartin PF04388.12 CDO76754.1 - 4.5 5.8 10.3 5.7 5.5 10.3 1.1 1 0 0 1 1 1 0 Hamartin protein LIM PF00412.22 CDO76755.1 - 2.5e-20 72.4 10.2 4.5e-12 46.0 0.6 2.4 2 1 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.10 CDO76755.1 - 0.00012 22.1 12.2 0.074 13.2 0.7 3.3 3 0 0 3 3 3 2 Zinc ribbon domain zf_UBZ PF18439.1 CDO76755.1 - 0.0075 15.8 9.3 3.4 7.3 0.2 4.5 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 CDO76755.1 - 0.074 13.1 18.5 0.38 10.8 3.3 3.3 2 2 0 2 2 2 0 Double zinc ribbon RecO_C PF02565.15 CDO76755.1 - 0.15 11.9 3.4 0.56 10.0 0.5 2.2 2 0 0 2 2 2 0 Recombination protein O C terminal zinc_ribbon_2 PF13240.6 CDO76755.1 - 0.39 10.5 18.3 10 6.0 0.4 5.2 5 0 0 5 5 5 0 zinc-ribbon domain Ribosomal_L40e PF01020.17 CDO76755.1 - 1.9 8.4 9.4 0.12 12.2 2.0 2.6 2 0 0 2 2 2 0 Ribosomal L40e family DUF4428 PF14471.6 CDO76755.1 - 2.2 8.2 5.1 19 5.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) DUF1451 PF07295.11 CDO76755.1 - 2.4 8.2 16.1 0.64 10.0 3.2 2.7 2 1 0 2 2 2 0 Zinc-ribbon containing domain zf-MYND PF01753.18 CDO76755.1 - 6.9 6.9 12.8 18 5.5 0.9 3.6 3 1 0 3 3 3 0 MYND finger eIF-5a PF01287.20 CDO76756.1 - 5.7e-30 103.2 0.2 1e-29 102.4 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CDO76756.1 - 0.083 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain DivIC PF04977.15 CDO76758.1 - 0.05 13.4 1.1 7 6.5 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 CDO76758.1 - 0.39 11.2 5.7 4.9 7.7 2.0 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Complex1_LYR PF05347.15 CDO76760.1 - 1.7e-10 40.8 0.5 2.7e-10 40.2 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CDO76760.1 - 0.00051 20.7 0.1 0.00069 20.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Spermine_synth PF01564.17 CDO76760.1 - 0.16 11.4 0.0 0.5 9.8 0.0 1.7 1 1 1 2 2 2 0 Spermine/spermidine synthase domain PP28 PF10252.9 CDO76761.1 - 5.6e-23 81.2 20.8 5.6e-23 81.2 20.8 3.2 1 1 2 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Sporozoite_P67 PF05642.11 CDO76761.1 - 0.54 8.3 6.8 0.7 7.9 6.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3246 PF11596.8 CDO76761.1 - 0.94 8.9 5.0 1.4 8.3 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) PPR_long PF17177.4 CDO76762.1 - 0.094 12.1 0.1 1.1 8.5 0.0 2.4 2 1 1 3 3 3 0 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 CDO76762.1 - 0.18 12.0 0.0 14 6.0 0.0 3.7 5 0 0 5 5 5 0 PPR repeat family RRM_1 PF00076.22 CDO76763.1 - 2.1e-10 40.2 0.0 2e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDO76763.1 - 0.019 14.9 0.0 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RINGv PF12906.7 CDO76764.1 - 3.5e-06 27.1 7.3 3.5e-06 27.1 7.3 1.7 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 CDO76764.1 - 0.0015 18.8 6.3 0.0033 17.7 6.3 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 CDO76764.1 - 0.0024 18.0 3.7 0.0024 18.0 3.7 1.6 2 0 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 CDO76764.1 - 0.26 11.2 5.0 0.57 10.1 5.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO76764.1 - 0.34 11.0 6.6 0.24 11.4 4.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger PHD_4 PF16866.5 CDO76764.1 - 0.35 11.0 6.7 0.59 10.3 6.7 1.3 1 0 0 1 1 1 0 PHD-finger eIF2_C PF09173.11 CDO76765.1 - 7.5e-35 119.1 0.4 1.8e-34 117.8 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CDO76765.1 - 5.4e-21 75.0 1.9 8.2e-20 71.2 1.9 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CDO76765.1 - 5.6e-11 42.7 1.6 7.6e-11 42.2 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 CDO76765.1 - 0.0018 18.2 0.7 0.026 14.4 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CDO76765.1 - 0.01 15.8 2.1 0.011 15.7 0.3 1.9 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CDO76765.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gp_dh_C PF02800.20 CDO76766.1 - 5e-70 234.2 0.1 6.7e-70 233.7 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CDO76766.1 - 4.4e-34 116.9 0.0 1.3e-33 115.3 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain HET PF06985.11 CDO76767.1 - 9.9e-06 26.0 0.1 1.5e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SDA1 PF05285.12 CDO76768.1 - 1.5e-05 24.6 2.8 3.4e-05 23.5 2.8 1.5 1 0 0 1 1 1 1 SDA1 Amelotin PF15757.5 CDO76768.1 - 0.051 13.2 0.2 0.097 12.2 0.2 1.4 1 0 0 1 1 1 0 Amelotin Pox_Ag35 PF03286.14 CDO76768.1 - 0.35 10.6 9.5 0.09 12.6 1.6 2.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF2457 PF10446.9 CDO76768.1 - 2.6 7.1 12.6 0.1 11.7 5.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 CDO76768.1 - 9.4 6.1 10.9 0.86 9.5 2.2 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RasGEF PF00617.19 CDO76769.1 - 1.3e-29 103.7 0.0 2.2e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CDO76769.1 - 3.6e-09 36.8 0.3 9.3e-09 35.5 0.3 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Aconitase PF00330.20 CDO76770.1 - 7.2e-155 516.5 0.0 9e-155 516.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CDO76770.1 - 1.6e-45 154.7 0.0 3e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Fungal_trans PF04082.18 CDO76771.1 - 7.4e-11 41.6 0.1 2.4e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 CDO76772.1 - 2.2e-24 85.7 0.4 4.5e-24 84.8 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CDO76772.1 - 1.2e-06 28.5 0.0 3.4e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 CDO76774.1 - 1.4e-21 76.7 0.7 2.7e-21 75.8 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CDO76774.1 - 2.1e-05 24.5 0.0 4.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 CDO76775.1 - 1.6e-14 53.8 0.0 5.9e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 CDO76775.1 - 6.5e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Amidase PF01425.21 CDO76776.1 - 6.5e-67 226.4 0.0 9.2e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Amidase ADH_N PF08240.12 CDO76776.1 - 9.6e-24 83.4 0.1 2.1e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO76776.1 - 1.5e-17 63.8 0.0 5e-17 62.1 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CDO76776.1 - 1.3e-06 28.1 0.0 1.8e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CDO76776.1 - 0.00047 21.2 0.0 0.0011 20.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CDO76776.1 - 0.02 14.3 0.0 0.08 12.3 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WSN PF02206.18 CDO76776.1 - 0.12 12.3 0.3 0.5 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function BTB PF00651.31 CDO76777.1 - 6.5e-06 26.4 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF3437 PF11919.8 CDO76777.1 - 0.0093 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Amidase PF01425.21 CDO76779.1 - 1.8e-76 257.9 0.0 8e-76 255.8 0.0 1.8 1 1 0 1 1 1 1 Amidase zf-CCCH_4 PF18044.1 CDO76780.1 - 1.7e-09 37.2 6.6 3.5e-05 23.5 0.6 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CDO76780.1 - 4.8e-09 36.9 4.9 0.00038 21.1 0.3 2.4 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 CDO76780.1 - 2.7e-06 27.2 12.8 2.7e-05 24.0 1.7 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CDO76780.1 - 4.3e-06 26.5 5.4 0.0003 20.6 0.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CDO76780.1 - 0.00065 19.9 0.4 0.0011 19.1 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDO76780.1 - 6.2 7.4 11.9 0.23 12.0 2.3 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Pkinase PF00069.25 CDO76781.1 - 2.3e-50 171.4 0.0 1.1e-42 146.3 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76781.1 - 8.9e-22 77.6 0.0 5.7e-16 58.6 0.0 2.9 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CDO76781.1 - 0.0021 17.4 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDO76781.1 - 0.047 13.0 0.0 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO76781.1 - 0.06 13.3 0.3 0.098 12.6 0.3 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO76781.1 - 0.11 11.4 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CDO76781.1 - 0.25 10.3 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 6PGD PF00393.19 CDO76782.1 - 3.7e-78 262.8 0.1 8.2e-56 189.5 0.0 2.1 2 0 0 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain BCDHK_Adom3 PF10436.9 CDO76782.1 - 2.3e-61 206.4 0.0 9.2e-61 204.4 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase NAD_binding_2 PF03446.15 CDO76782.1 - 9e-33 113.7 0.0 1.6e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HATPase_c PF02518.26 CDO76782.1 - 3.2e-13 50.2 0.0 2e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3HCDH_N PF02737.18 CDO76782.1 - 2.8e-09 37.1 0.0 5.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 CDO76782.1 - 1.4e-05 25.1 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 CDO76782.1 - 0.0031 16.9 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HATPase_c_3 PF13589.6 CDO76782.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UDPG_MGDP_dh_N PF03721.14 CDO76782.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3719 PF12516.8 CDO76782.1 - 0.043 13.5 0.3 0.61 9.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) F420_oxidored PF03807.17 CDO76782.1 - 0.11 13.1 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 CDO76782.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PAS_9 PF13426.7 CDO76783.1 - 9.4e-18 64.4 0.0 6.8e-07 29.5 0.0 3.6 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 CDO76783.1 - 2.1e-11 44.0 0.1 1.3e-05 25.4 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.12 CDO76783.1 - 3.1e-11 43.4 0.0 1.4e-05 25.3 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 CDO76783.1 - 8.2e-11 41.9 0.0 0.00013 22.0 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 CDO76783.1 - 0.0011 19.0 0.0 0.039 14.1 0.0 2.4 2 0 0 2 2 2 1 PAS domain Fungal_TACC PF12709.7 CDO76783.1 - 0.055 13.9 0.2 0.1 13.1 0.2 1.3 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4763 PF15960.5 CDO76783.1 - 0.26 10.6 0.1 0.44 9.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Cep57_MT_bd PF06657.13 CDO76783.1 - 0.64 10.5 1.6 0.66 10.5 0.3 1.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 F_bP_aldolase PF01116.20 CDO76784.1 - 9.2e-91 304.2 0.0 1e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Lipase_GDSL_2 PF13472.6 CDO76784.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Torsin PF06309.11 CDO76784.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Torsin TFIIA PF03153.13 CDO76785.1 - 6 6.8 10.7 11 5.8 10.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HhH-GPD PF00730.25 CDO76786.1 - 0.00048 20.5 0.0 0.00052 20.4 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_L16 PF00252.18 CDO76787.1 - 2.5e-46 157.0 0.0 3e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RTBV_P46 PF06216.11 CDO76787.1 - 0.061 12.2 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Glyco_hydro_20 PF00728.22 CDO76788.1 - 8e-62 209.7 0.0 1.3e-61 209.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 CDO76788.1 - 3.5e-13 50.4 0.0 8.4e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 CDO76788.1 - 4.3e-05 24.3 0.0 0.00026 21.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_97 PF10566.9 CDO76788.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 APH PF01636.23 CDO76789.1 - 1.7e-15 57.6 0.1 2.4e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO76789.1 - 6.3e-05 22.7 0.0 9.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CDO76789.1 - 0.0044 16.6 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 CDO76789.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.14 CDO76789.1 - 0.12 11.7 0.3 0.26 10.6 0.2 1.6 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family OPT PF03169.15 CDO76790.1 - 3.7e-55 187.7 25.0 4.5e-55 187.4 25.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.25 CDO76791.1 - 2.8e-59 200.6 0.0 5.9e-57 193.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76791.1 - 3e-28 98.8 0.0 2.1e-27 96.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO76791.1 - 0.00033 20.1 0.3 0.00067 19.1 0.3 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CDO76791.1 - 0.019 13.9 0.1 0.071 12.0 0.0 1.7 1 1 1 2 2 2 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CDO76791.1 - 0.075 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 CDO76791.1 - 0.17 10.6 0.9 0.45 9.2 1.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 CDO76791.1 - 0.18 11.4 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4410 PF14366.6 CDO76792.1 - 0.19 11.6 0.6 0.62 10.0 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) PGA2 PF07543.12 CDO76793.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Hexapep PF00132.24 CDO76794.1 - 6.4e-07 28.8 19.4 0.005 16.5 0.2 4.1 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CDO76794.1 - 0.02 14.7 5.8 0.02 14.7 5.8 2.9 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Meleagrin PF08189.11 CDO76794.1 - 0.098 12.4 0.9 0.18 11.5 0.9 1.5 1 0 0 1 1 1 0 Meleagrin/Cygnin family BTB PF00651.31 CDO76795.1 - 2e-07 31.2 0.0 4.4e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain fn3_2 PF16893.5 CDO76796.1 - 6.8e-39 131.9 0.3 1.4e-38 130.9 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 CDO76796.1 - 1.9e-26 91.7 0.2 3.1e-26 91.0 0.2 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 CDO76796.1 - 3.1e-10 40.3 0.0 4.8e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CDO76796.1 - 7.5e-08 32.2 0.1 1.1e-06 28.5 0.1 2.3 1 1 0 1 1 1 1 twin BRCT domain fn3 PF00041.21 CDO76796.1 - 6.3e-05 23.2 0.7 0.00028 21.2 0.7 2.1 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 CDO76796.1 - 0.00013 22.3 0.0 0.00023 21.5 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 CDO76796.1 - 0.0028 17.9 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) DUF4470 PF14737.6 CDO76798.1 - 3.4e-20 72.1 0.0 1.2e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 CDO76798.1 - 2.5e-09 37.1 17.3 5.3e-09 36.0 17.3 1.6 1 0 0 1 1 1 1 MYND finger Rhodanese_C PF12368.8 CDO76798.1 - 0.1 13.0 5.0 0.29 11.5 5.0 1.8 1 0 0 1 1 1 0 Rhodanase C-terminal zf-C6H2 PF15801.5 CDO76798.1 - 0.2 12.0 9.6 0.54 10.6 9.6 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Transp_cyt_pur PF02133.15 CDO76799.1 - 3.8e-95 319.3 40.9 4.5e-95 319.0 40.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sel1 PF08238.12 CDO76800.1 - 2.2e-18 66.2 15.9 2.7e-06 27.9 0.0 7.2 8 0 0 8 8 8 4 Sel1 repeat ADH_N PF08240.12 CDO76800.1 - 1.3e-08 34.7 0.4 2.6e-08 33.7 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO76800.1 - 5.2e-07 29.7 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPR_8 PF13181.6 CDO76800.1 - 0.00037 20.5 1.8 0.0043 17.2 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDO76800.1 - 0.003 17.6 3.8 0.054 13.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CDO76800.1 - 0.17 11.7 3.6 0.52 10.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5560 PF17715.1 CDO76801.1 - 0.13 11.7 0.3 0.29 10.6 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5560) Atg14 PF10186.9 CDO76801.1 - 3.7 6.5 7.2 0.32 10.0 0.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2826 PF11442.8 CDO76803.1 - 0.13 12.1 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) RVT_2 PF07727.14 CDO76804.1 - 5e-81 271.9 0.1 6.9e-81 271.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_polI_A34 PF08208.11 CDO76804.1 - 0.33 11.0 4.5 0.66 10.0 4.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 ASFV_J13L PF05568.11 CDO76805.1 - 0.0042 16.9 2.8 0.0087 15.8 2.8 1.5 1 0 0 1 1 1 1 African swine fever virus J13L protein CHASE9 PF17153.4 CDO76805.1 - 0.011 15.9 0.3 0.025 14.7 0.3 1.6 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular Transposase_21 PF02992.14 CDO76806.1 - 9.3e-06 25.0 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Carb_bind PF10645.9 CDO76806.1 - 0.028 14.7 0.8 0.079 13.2 0.8 1.8 1 0 0 1 1 1 0 Carbohydrate binding DUF4218 PF13960.6 CDO76806.1 - 0.052 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF816 PF05674.12 CDO76807.1 - 0.2 11.6 0.0 0.27 11.2 0.0 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Transposase_21 PF02992.14 CDO76809.1 - 4.2e-16 58.8 0.0 7.7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 CDO76809.1 - 0.0078 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF4218 PF13960.6 CDO76809.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Plavaka PF18759.1 CDO76810.1 - 1.6e-26 93.3 0.0 3.2e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase OEP PF02321.18 CDO76810.1 - 0.19 11.5 3.0 0.31 10.8 3.0 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein Plavaka PF18759.1 CDO76811.1 - 2.2e-109 365.6 0.1 6.6e-108 360.8 0.1 2.4 1 1 0 1 1 1 1 Plavaka transposase Glyco_hydro_cc PF11790.8 CDO76811.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core DUF1073 PF06381.11 CDO76811.1 - 0.19 10.5 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) zf-C2H2_9 PF16293.5 CDO76811.1 - 0.56 10.1 0.0 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Dynamitin PF04912.14 CDO76812.1 - 0.0026 17.2 0.7 0.0038 16.6 0.7 1.2 1 0 0 1 1 1 1 Dynamitin SKA2 PF16740.5 CDO76812.1 - 0.032 14.0 2.2 0.11 12.3 2.2 1.8 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 HTH_49 PF18010.1 CDO76812.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain ABC_tran_Xtn PF12848.7 CDO76812.1 - 0.31 11.1 7.3 0.73 9.9 7.3 1.6 1 0 0 1 1 1 0 ABC transporter Mod_r PF07200.13 CDO76812.1 - 1.4 9.1 10.0 4.8 7.3 3.3 3.1 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.9 CDO76815.1 - 0.00017 21.6 10.0 0.0028 17.7 2.6 2.3 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 CDO76815.1 - 0.0021 17.0 6.9 0.0026 16.7 6.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 CDO76815.1 - 0.003 17.6 4.9 0.03 14.4 0.5 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) FPP PF05911.11 CDO76815.1 - 0.0048 15.2 4.5 0.0065 14.7 4.5 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Cortex-I_coil PF09304.10 CDO76815.1 - 0.034 14.4 0.6 0.12 12.7 0.2 2.0 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF4200 PF13863.6 CDO76815.1 - 0.037 14.4 3.0 0.37 11.2 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.11 CDO76815.1 - 0.06 13.9 3.4 0.63 10.6 3.2 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF713 PF05218.14 CDO76815.1 - 0.21 11.3 1.1 4.6 7.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF713) EMP24_GP25L PF01105.24 CDO76815.1 - 0.23 11.4 2.9 4.4 7.2 0.2 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 CDO76815.1 - 0.27 9.4 2.8 3.1 5.9 0.2 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ADIP PF11559.8 CDO76815.1 - 0.41 10.7 9.5 0.38 10.8 0.9 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3552 PF12072.8 CDO76815.1 - 0.77 9.1 8.9 2.9 7.3 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Fez1 PF06818.15 CDO76815.1 - 0.89 10.0 9.8 0.25 11.8 2.2 2.1 1 1 1 2 2 2 0 Fez1 HIP1_clath_bdg PF16515.5 CDO76815.1 - 0.94 10.1 8.1 0.95 10.1 0.7 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 KxDL PF10241.9 CDO76815.1 - 2.1 8.7 5.8 5.5 7.4 0.2 2.9 1 1 1 3 3 3 0 Uncharacterized conserved protein DUF16 PF01519.16 CDO76815.1 - 9.1 6.8 6.8 23 5.5 0.8 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 Sad1_UNC PF07738.13 CDO76816.1 - 2.7e-10 40.4 0.0 0.0016 18.5 0.0 2.9 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal Catalase-rel PF06628.12 CDO76818.1 - 0.15 12.3 0.1 12 6.2 0.0 3.2 4 0 0 4 4 4 0 Catalase-related immune-responsive F-box PF00646.33 CDO76819.1 - 4.1e-08 32.9 0.0 9e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO76819.1 - 7.1e-08 32.2 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CDO76819.1 - 0.0058 16.5 1.6 0.019 14.8 0.0 2.5 2 1 1 3 3 3 1 F-box RNA_pol_Rpb2_2 PF04561.14 CDO76820.1 - 0.04 13.5 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Gti1_Pac2 PF09729.9 CDO76820.1 - 0.77 9.8 3.1 1.7 8.7 3.1 1.6 1 1 0 1 1 1 0 Gti1/Pac2 family PPP4R2 PF09184.11 CDO76820.1 - 1.1 8.8 16.4 1.3 8.5 16.4 1.2 1 0 0 1 1 1 0 PPP4R2 Phosphodiest PF01663.22 CDO76821.1 - 3.6e-11 43.2 0.2 1.3e-10 41.4 0.1 1.8 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CDO76821.1 - 0.0039 16.6 0.0 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 Sulfatase Rhodanese PF00581.20 CDO76823.1 - 1.2e-07 32.2 0.0 2.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain F-box-like PF12937.7 CDO76824.1 - 3.6e-08 33.2 1.5 9e-08 31.9 1.5 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 CDO76825.1 - 0.0043 16.9 0.0 0.0088 15.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CDO76825.1 - 0.015 15.7 0.5 0.67 10.5 0.0 3.4 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CDO76825.1 - 0.063 13.1 0.1 1.7 8.5 0.0 2.9 3 0 0 3 3 3 0 Leucine rich repeat GIDA PF01134.22 CDO76826.1 - 1.9e-108 363.1 0.0 3.7e-108 362.1 0.0 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CDO76826.1 - 1.2e-55 188.9 0.0 1.8e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain DUF3898 PF13037.6 CDO76826.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3898) zf-CSL PF05207.13 CDO76827.1 - 1.2e-22 79.4 1.0 1.2e-22 79.4 1.0 1.7 2 0 0 2 2 2 1 CSL zinc finger FAM176 PF14851.6 CDO76827.1 - 0.05 13.3 2.1 0.068 12.8 2.1 1.2 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 CDO76827.1 - 0.077 12.3 5.0 0.081 12.3 5.0 1.0 1 0 0 1 1 1 0 BUD22 Terminase_GpA PF05876.12 CDO76827.1 - 0.091 11.3 0.5 0.11 11.0 0.5 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) GAGA PF09237.11 CDO76827.1 - 0.12 12.3 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 GAGA factor Nop16 PF09420.10 CDO76827.1 - 0.13 12.2 0.6 0.2 11.7 0.6 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 CDC45 PF02724.14 CDO76827.1 - 2.1 6.6 6.0 2.1 6.5 6.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 CDO76827.1 - 3 6.9 8.9 3.3 6.8 8.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein F-box PF00646.33 CDO76828.1 - 1.4e-06 28.0 0.9 6.4e-06 25.9 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CDO76828.1 - 1.3e-05 25.0 0.1 4e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CDO76828.1 - 0.013 15.4 0.2 0.1 12.5 0.0 2.3 2 0 0 2 2 2 0 F-box NOA36 PF06524.12 CDO76829.1 - 0.1 11.9 1.8 0.15 11.4 1.8 1.1 1 0 0 1 1 1 0 NOA36 protein ATHILA PF03078.15 CDO76829.1 - 3.8 6.2 4.8 5.5 5.7 4.8 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family Rad60-SLD PF11976.8 CDO76833.1 - 2.5e-08 33.6 0.3 4.2e-08 32.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CDO76833.1 - 0.02 14.7 0.2 0.028 14.2 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin family UreE_N PF02814.15 CDO76833.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Solute_trans_a PF03619.16 CDO76835.1 - 1.2e-44 152.8 4.3 1.6e-44 152.5 4.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF5572 PF17733.1 CDO76838.1 - 2.8e-19 68.7 1.0 5e-19 67.9 1.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5572) YbaB_DNA_bd PF02575.16 CDO76839.1 - 0.57 10.4 2.7 0.73 10.1 0.2 2.1 1 1 1 2 2 2 0 YbaB/EbfC DNA-binding family adh_short PF00106.25 CDO76840.1 - 3.9e-24 85.2 0.5 5.8e-24 84.6 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO76840.1 - 1.4e-23 83.7 0.8 1.8e-23 83.3 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO76840.1 - 0.0011 18.9 0.7 0.0018 18.2 0.6 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CDO76840.1 - 0.024 14.5 0.3 0.044 13.7 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 CDO76840.1 - 0.053 13.4 0.9 0.11 12.4 0.1 1.9 2 1 0 2 2 2 0 YjeF-related protein N-terminus DNA_processg_A PF02481.15 CDO76840.1 - 0.63 9.2 4.0 0.56 9.4 0.1 2.0 2 0 0 2 2 2 0 DNA recombination-mediator protein A PIP5K PF01504.18 CDO76841.1 - 2e-49 168.2 1.7 2.6e-39 135.1 0.0 2.6 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase DIM1 PF02966.16 CDO76842.1 - 6.4e-68 226.6 0.0 7.2e-68 226.5 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CDO76842.1 - 3.9e-05 23.6 0.0 5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CDO76842.1 - 0.013 15.8 0.2 0.02 15.2 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin-like Thioredox_DsbH PF03190.15 CDO76842.1 - 0.13 12.2 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Pro_isomerase PF00160.21 CDO76843.1 - 8e-49 165.9 0.1 9.4e-49 165.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2470 PF10615.9 CDO76844.1 - 5.1e-16 59.1 0.0 1.2e-15 57.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 CDO76844.1 - 2.3e-11 43.9 1.1 2.7e-10 40.4 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4499) 2TM PF13239.6 CDO76844.1 - 0.22 11.9 4.2 0.093 13.0 1.9 1.6 1 1 0 1 1 1 0 2TM domain Neuromodulin PF06614.11 CDO76845.1 - 1.5 9.0 8.8 2.9 8.0 4.9 2.2 2 0 0 2 2 2 0 Neuromodulin Cu_amine_oxid PF01179.20 CDO76846.1 - 4.5e-157 523.2 0.0 5.3e-157 522.9 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 CDO76846.1 - 2.7e-11 43.8 0.0 5.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 CDO76846.1 - 3.1e-05 24.1 0.0 7.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Adeno_E1A PF02703.14 CDO76846.1 - 0.033 13.8 0.5 0.065 12.8 0.1 1.6 2 0 0 2 2 2 0 Early E1A protein Med25_VWA PF11265.8 CDO76847.1 - 0.015 15.1 0.0 4.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 25 von Willebrand factor type A Yae1_N PF09811.9 CDO76848.1 - 1.1e-08 34.6 5.4 2e-08 33.8 5.4 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal BTB_2 PF02214.22 CDO76848.1 - 0.081 13.3 0.0 0.68 10.3 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain NmrA PF05368.13 CDO76850.1 - 9.5e-33 113.7 0.0 1.2e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CDO76850.1 - 1.8e-07 31.2 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding FGGY_N PF00370.21 CDO76851.1 - 0.0017 18.0 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain 2OG-FeII_Oxy_2 PF13532.6 CDO76852.1 - 3.5e-29 102.4 0.0 4.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acetyltransf_3 PF13302.7 CDO76853.1 - 2.8e-12 47.5 0.0 3.8e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO76853.1 - 0.0001 22.5 0.0 0.00025 21.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO76853.1 - 0.062 13.7 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Homeodomain PF00046.29 CDO76855.1 - 2.5e-06 27.2 0.2 2.5e-06 27.2 0.2 2.1 2 0 0 2 2 2 1 Homeodomain SLD3 PF08639.10 CDO76856.1 - 4.5e-13 48.8 7.6 4.2e-12 45.6 0.3 3.1 1 1 2 3 3 3 3 DNA replication regulator SLD3 Ank_5 PF13857.6 CDO76857.1 - 7.1e-17 61.3 0.5 1.3e-09 38.1 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CDO76857.1 - 1.2e-14 54.6 0.0 1.7e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDO76857.1 - 4.7e-13 49.4 0.1 0.00078 20.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CDO76857.1 - 8.4e-12 44.2 0.1 2.1e-06 27.6 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CDO76857.1 - 2.8e-10 40.2 0.9 1.2e-06 28.7 0.3 2.7 3 0 0 3 3 3 2 Ankyrin repeat Sec7_N PF12783.7 CDO76858.1 - 2.7e-52 176.8 7.8 4.8e-52 176.0 1.6 3.5 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 CDO76858.1 - 4.3e-42 144.2 1.3 9.4e-27 93.5 0.4 3.8 3 1 0 3 3 3 3 C-terminal region of Mon2 protein DCB PF16213.5 CDO76858.1 - 6.4e-39 133.4 2.6 1.9e-38 131.9 2.6 1.9 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 CDO76858.1 - 6.4e-07 29.1 0.0 7.6e-06 25.7 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) RTP1_C1 PF10363.9 CDO76858.1 - 0.0037 17.4 0.3 0.78 9.9 0.0 3.9 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 CDO76858.1 - 0.25 11.7 1.0 36 5.0 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat Glyco_transf_15 PF01793.16 CDO76859.1 - 1.5e-128 428.6 10.0 2e-128 428.2 10.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase BORCS8 PF10167.9 CDO76859.1 - 0.03 14.3 0.0 0.095 12.6 0.0 1.7 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 SEP PF08059.13 CDO76860.1 - 2e-25 89.1 0.0 4.5e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CDO76860.1 - 5.5e-17 61.8 0.0 8.6e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 UBX domain UPF0547 PF10571.9 CDO76861.1 - 0.0079 16.3 6.1 0.015 15.3 0.7 3.1 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 IBR PF01485.21 CDO76861.1 - 0.63 10.3 16.4 0.64 10.3 0.2 4.1 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain Molybdopterin_N PF18364.1 CDO76861.1 - 3.2 7.9 6.5 10 6.2 1.3 3.1 3 0 0 3 3 3 0 Molybdopterin oxidoreductase N-terminal domain zinc_ribbon_2 PF13240.6 CDO76861.1 - 3.7 7.4 8.9 0.22 11.3 0.7 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Pkinase PF00069.25 CDO76862.1 - 2.9e-17 62.9 0.0 3.4e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76862.1 - 1.8e-07 30.8 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO76863.1 - 2.2e-51 174.9 0.0 6e-51 173.5 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO76863.1 - 0.071 13.0 0.1 0.36 10.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Aldedh PF00171.22 CDO76864.1 - 4e-23 81.7 1.2 3.9e-18 65.2 0.7 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 CDO76864.1 - 0.087 11.9 0.0 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) ICMT PF04140.14 CDO76865.1 - 1.2e-15 57.7 0.7 1.6e-14 54.1 0.2 2.3 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO76865.1 - 1.2e-10 41.7 2.3 5.9e-10 39.5 2.3 2.2 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO76865.1 - 2.3e-07 30.0 0.2 3e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 CDO76866.1 - 8.7e-16 58.1 1.5 4.3e-15 55.9 1.5 2.1 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO76866.1 - 3.4e-10 40.3 2.2 5.3e-09 36.4 1.2 2.2 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO76866.1 - 1.6e-06 27.2 0.1 2.3e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NapE PF06796.11 CDO76866.1 - 0.47 10.0 5.7 0.069 12.7 1.2 2.0 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Ribosomal_L14 PF00238.19 CDO76867.1 - 9.1e-46 154.9 1.7 1e-45 154.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hexokinase_2 PF03727.16 CDO76868.1 - 1.7e-82 276.5 0.0 2.4e-82 276.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CDO76868.1 - 5.2e-68 228.9 0.0 7.1e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 CDO76868.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain ICMT PF04140.14 CDO76869.1 - 2.4e-15 56.7 2.2 6.7e-14 52.1 0.3 2.5 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO76869.1 - 4.6e-10 39.8 3.3 2e-07 31.3 1.1 2.5 1 1 0 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO76869.1 - 8.2e-07 28.1 0.5 1.3e-06 27.5 0.5 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 CDO76870.1 - 1.5e-14 54.2 0.1 9.4e-14 51.6 0.1 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO76870.1 - 5.7e-10 39.5 1.5 1.6e-09 38.1 1.0 1.9 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO76870.1 - 7.7e-06 24.9 0.1 1.1e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CDO76870.1 - 0.07 12.6 0.3 0.11 12.0 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) ICMT PF04140.14 CDO76871.1 - 2.3e-13 50.4 0.1 5.2e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO76871.1 - 1.6e-11 44.6 1.4 1e-10 41.9 0.5 2.2 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO76871.1 - 0.021 13.6 0.0 0.036 12.8 0.0 1.3 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 CDO76872.1 - 3.6e-08 33.7 0.1 2.5e-07 31.0 0.1 2.3 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO76872.1 - 1.2e-07 32.0 0.5 3.8e-06 27.3 0.2 2.6 2 1 2 4 4 4 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO76872.1 - 4.1e-06 25.8 0.0 5.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MaoC_dehydrat_N PF13452.6 CDO76874.1 - 0.016 15.4 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Alpha-amylase_C PF02806.18 CDO76874.1 - 0.039 14.4 0.0 0.062 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain DUF4449 PF14613.6 CDO76875.1 - 9.5e-14 51.8 0.0 9.5e-14 51.8 0.0 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) DUF1800 PF08811.11 CDO76875.1 - 0.15 11.0 0.1 0.15 11.0 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1800) DUF3069 PF11269.8 CDO76875.1 - 0.89 9.8 3.9 0.93 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) DUF883 PF05957.13 CDO76875.1 - 3.4 8.3 19.5 6.3 7.5 0.1 4.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) RVT_1 PF00078.27 CDO76876.1 - 2e-36 125.6 0.0 3.2e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO76876.1 - 3.3e-09 37.1 0.0 1.1e-08 35.3 0.0 1.9 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 CDO76876.1 - 0.0043 17.7 0.1 0.012 16.3 0.1 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FTCD_C PF04961.12 CDO76877.1 - 0.0063 16.3 4.3 0.017 14.9 4.3 1.7 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase RNA_pol PF00940.19 CDO76877.1 - 0.028 13.3 1.1 0.042 12.7 1.1 1.2 1 0 0 1 1 1 0 DNA-dependent RNA polymerase DUF4231 PF14015.6 CDO76877.1 - 0.066 13.7 1.8 0.16 12.5 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) FeoB_Cyto PF17910.1 CDO76877.1 - 0.068 13.7 0.8 0.28 11.8 0.8 2.1 1 0 0 1 1 1 0 FeoB cytosolic helical domain EHN PF06441.12 CDO76878.1 - 3.4e-33 114.2 1.6 5.7e-33 113.5 0.1 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CDO76878.1 - 5.3e-07 29.5 0.0 8.7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO76878.1 - 5.7e-05 23.8 3.0 0.00044 20.9 3.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Homeobox_KN PF05920.11 CDO76879.1 - 3.4e-19 68.5 0.1 7.4e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CDO76879.1 - 4.9e-05 23.1 0.0 9.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain rve PF00665.26 CDO76881.1 - 8.8e-22 77.5 0.0 1.3e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO76881.1 - 1.4e-08 34.4 0.0 3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO76881.1 - 7.4e-05 22.4 0.1 0.00012 21.7 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.14 CDO76882.1 - 5.3e-50 170.3 0.2 9.6e-50 169.5 0.1 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Plavaka PF18759.1 CDO76885.1 - 2.3e-65 220.9 0.0 2.7e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase SnoaL_2 PF12680.7 CDO76885.1 - 0.094 13.4 0.1 0.28 11.8 0.0 1.8 2 0 0 2 2 2 0 SnoaL-like domain 2OG-FeII_Oxy_3 PF13640.6 CDO76887.1 - 0.0079 17.1 0.0 0.019 15.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ERM PF00769.19 CDO76890.1 - 0.16 11.8 24.2 0.32 10.8 24.2 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Plavaka PF18759.1 CDO76892.1 - 3.3e-108 361.8 0.0 4.5e-108 361.3 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Pkinase_fungal PF17667.1 CDO76893.1 - 1.2e-45 156.0 0.0 2.9e-45 154.8 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CDO76893.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 CDO76893.1 - 0.044 13.7 0.1 0.095 12.6 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mago_nashi PF02792.14 CDO76894.1 - 1.1e-72 242.8 0.2 1.2e-72 242.6 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Hce2 PF14856.6 CDO76895.1 - 0.014 15.6 0.9 0.086 13.1 0.0 2.5 1 1 2 3 3 3 0 Pathogen effector; putative necrosis-inducing factor Tim54 PF11711.8 CDO76895.1 - 0.035 12.9 1.4 0.047 12.5 1.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Caprin-1_C PF12287.8 CDO76895.1 - 0.079 13.1 3.8 0.1 12.7 3.8 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term PRP21_like_P PF12230.8 CDO76895.1 - 0.49 10.2 4.9 0.66 9.8 4.9 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein NESP55 PF06390.12 CDO76895.1 - 2.9 7.4 13.5 4.4 6.8 13.5 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Glyco_hydro_79C PF16862.5 CDO76896.1 - 1.2e-15 58.3 0.7 2.4e-15 57.2 0.7 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Pkinase PF00069.25 CDO76897.1 - 1.3e-21 77.1 0.0 1.6e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO76897.1 - 1.7e-10 40.6 0.0 2.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO76897.1 - 5.4e-07 28.7 0.1 7.3e-07 28.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO76897.1 - 0.02 14.8 0.1 0.05 13.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family NACHT PF05729.12 CDO76899.1 - 4.8e-09 36.3 0.0 1.3e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CDO76899.1 - 5e-05 23.8 0.1 0.00013 22.4 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CDO76899.1 - 0.00043 20.6 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 CDO76899.1 - 0.21 10.8 0.0 0.47 9.6 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain OTCace_N PF02729.21 CDO76900.1 - 3.6e-45 153.6 0.0 5.5e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 CDO76900.1 - 1.1e-43 149.0 0.0 1.6e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF620 PF04788.12 CDO76900.1 - 0.056 12.9 0.6 0.1 12.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF620) Glycogen_syn PF05693.13 CDO76901.1 - 0 1102.3 0.0 0 1102.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 CDO76901.1 - 2.9e-06 27.2 0.1 9.6e-06 25.5 0.1 1.9 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 CDO76901.1 - 1.1e-05 25.1 0.0 0.0013 18.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CDO76901.1 - 2.4e-05 24.8 0.0 5.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 CDO76901.1 - 6.3e-05 23.0 0.3 0.00015 21.8 0.3 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CDO76901.1 - 7.7e-05 23.1 0.0 0.027 14.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Ribosomal_L27_C PF18471.1 CDO76901.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L27 protein C-terminal domain CBF PF03914.17 CDO76902.1 - 2.2e-39 135.2 0.3 2.2e-39 135.2 0.3 2.1 2 0 0 2 2 2 1 CBF/Mak21 family GMC_oxred_N PF00732.19 CDO76903.1 - 7.7e-49 166.6 0.0 1e-48 166.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO76903.1 - 1.3e-20 74.4 0.1 3.4e-20 73.1 0.1 1.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CDO76903.1 - 0.0001 21.5 0.1 0.19 10.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 CDO76903.1 - 0.00058 19.0 0.0 0.00093 18.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CDO76903.1 - 0.001 18.8 0.6 0.012 15.2 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDO76903.1 - 0.0067 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDO76903.1 - 0.0067 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Redoxin PF08534.10 CDO76904.1 - 1.3e-13 50.9 0.0 1.8e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CDO76904.1 - 6.9e-06 26.0 0.0 9.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF824 PF05688.11 CDO76904.1 - 0.014 15.2 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) MRG PF05712.13 CDO76905.1 - 1.5e-57 194.1 0.0 2.1e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CDO76905.1 - 1.9e-09 37.3 0.4 3.4e-09 36.5 0.4 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Rubella_Capsid PF05750.11 CDO76905.1 - 0.056 13.0 4.6 0.1 12.2 4.6 1.3 1 0 0 1 1 1 0 Rubella capsid protein DDE_1 PF03184.19 CDO76906.1 - 2e-18 66.7 0.0 3.5e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CDO76906.1 - 2.4e-11 43.5 0.0 6.6e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 CDO76906.1 - 8.9e-06 25.3 0.0 2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.20 CDO76906.1 - 0.027 14.8 3.0 0.05 13.9 0.5 2.5 2 0 0 2 2 2 0 Transposase HTH_Tnp_ISL3 PF13542.6 CDO76906.1 - 0.03 13.7 0.1 0.18 11.3 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 CDO76906.1 - 0.031 14.1 0.0 0.15 11.9 0.0 2.2 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.6 CDO76906.1 - 0.032 14.0 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_24 PF13412.6 CDO76906.1 - 0.16 11.5 0.0 0.43 10.2 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Evr1_Alr PF04777.13 CDO76906.1 - 0.43 11.1 8.1 3.2 8.3 1.5 2.6 1 1 1 2 2 2 0 Erv1 / Alr family CAP_N PF01213.19 CDO76906.1 - 7.8 5.9 9.2 4.3 6.7 2.0 3.0 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Spore_coat_CotO PF14153.6 CDO76907.1 - 0.055 13.4 10.4 0.065 13.2 10.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF4407 PF14362.6 CDO76907.1 - 0.06 12.7 5.1 0.062 12.7 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-Q PF13094.6 CDO76907.1 - 0.12 12.6 10.3 0.17 12.1 10.3 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit U79_P34 PF03064.16 CDO76907.1 - 0.19 11.0 11.0 0.24 10.7 11.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 YlqD PF11068.8 CDO76907.1 - 0.2 12.0 13.4 0.31 11.4 13.4 1.2 1 0 0 1 1 1 0 YlqD protein Borrelia_P83 PF05262.11 CDO76907.1 - 0.31 9.5 7.8 0.25 9.8 7.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ObR_Ig PF18589.1 CDO76907.1 - 0.7 10.3 4.4 0.36 11.2 0.3 2.0 1 1 0 2 2 2 0 Obesity receptor immunoglobulin like domain DUF1664 PF07889.12 CDO76907.1 - 0.78 9.8 3.0 1.1 9.3 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3523 PF12037.8 CDO76907.1 - 1.3 8.3 18.9 1.8 7.9 18.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Menin PF05053.13 CDO76907.1 - 1.3 7.3 5.3 1.5 7.1 5.3 1.0 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 CDO76907.1 - 2.3 6.9 5.4 2.7 6.7 5.4 1.0 1 0 0 1 1 1 0 Presenilin HemX PF04375.14 CDO76907.1 - 2.8 7.2 12.4 3.6 6.8 12.4 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Rpp20 PF12328.8 CDO76907.1 - 2.8 7.9 8.7 5.3 7.0 8.7 1.5 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P ATP11 PF06644.11 CDO76907.1 - 3.1 7.5 9.7 3.8 7.2 9.7 1.1 1 0 0 1 1 1 0 ATP11 protein TSA PF03249.13 CDO76907.1 - 3.2 6.4 5.1 4 6.1 5.1 1.1 1 0 0 1 1 1 0 Type specific antigen Zn_clus PF00172.18 CDO76907.1 - 3.3 7.9 16.2 0.88 9.7 12.9 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop53 PF07767.11 CDO76907.1 - 5.2 6.4 19.0 6.6 6.0 19.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 CDO76907.1 - 6.6 6.5 10.1 8.2 6.2 10.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 CDO76907.1 - 8.9 5.1 11.9 11 4.8 11.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GPS2_interact PF15784.5 CDO76907.1 - 9.7 6.7 15.2 36 4.9 15.2 1.9 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF1104 PF06518.11 CDO76908.1 - 0.026 14.9 0.2 0.053 13.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) RT_RNaseH PF17917.1 CDO76909.1 - 1.1e-29 102.7 0.0 5e-15 55.7 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO76909.1 - 6.5e-29 99.9 0.0 5.3e-19 68.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDO76909.1 - 3.8e-17 62.1 0.3 7.3e-17 61.2 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO76909.1 - 5.1e-11 42.8 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CDO76909.1 - 1.5e-07 31.5 0.1 3e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 CDO76909.1 - 1.3e-06 28.2 0.0 2.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 CDO76910.1 - 1.1e-29 102.8 0.1 1.8e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO76910.1 - 5.4e-28 97.0 0.0 1.2e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CDO76911.1 - 1.1e-19 70.8 0.2 2.6e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO76911.1 - 3.9e-12 46.0 0.1 6e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO76911.1 - 3e-09 36.6 0.3 6.5e-09 35.5 0.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO76911.1 - 0.0016 18.2 0.0 0.0039 16.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF4820 PF16091.5 CDO76911.1 - 0.19 11.1 1.6 0.33 10.3 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) ENTH PF01417.20 CDO76913.1 - 1.6e-48 163.9 0.1 2.4e-48 163.3 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CDO76913.1 - 2.6e-08 33.2 0.1 5.4e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 ANTH domain UIM PF02809.20 CDO76913.1 - 5e-05 22.9 12.4 0.014 15.3 1.3 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif FXR_C3 PF16097.5 CDO76913.1 - 0.72 10.6 2.6 1.1 10.0 0.2 2.3 1 1 1 2 2 2 0 Fragile X-related 1 protein C-terminal region 3 GET2 PF08690.10 CDO76914.1 - 0.098 12.3 2.5 0.14 11.8 2.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF1746 PF08508.10 CDO76914.1 - 0.21 11.9 4.2 0.49 10.7 4.2 1.7 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1746) FtsX PF02687.21 CDO76914.1 - 0.23 11.9 7.7 6.1 7.4 3.4 2.6 2 0 0 2 2 2 0 FtsX-like permease family TrwB_AAD_bind PF10412.9 CDO76915.1 - 0.022 13.7 1.3 0.043 12.7 1.3 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF3813 PF12758.7 CDO76915.1 - 3.7 7.9 8.0 0.48 10.8 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Lentiviral_Tat PF02998.14 CDO76915.1 - 5.5 7.1 7.1 0.84 9.7 0.8 2.6 2 1 0 2 2 2 0 Lentiviral Tat protein Cpn60_TCP1 PF00118.24 CDO76916.1 - 7.9e-169 562.4 3.4 9e-169 562.2 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF627 PF04781.12 CDO76916.1 - 0.043 13.8 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF627) HXXEE PF13787.6 CDO76917.1 - 8.5 7.2 8.2 3.3e+02 2.1 9.4 2.5 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif HisG_C PF08029.11 CDO76918.1 - 0.024 14.8 0.0 0.082 13.1 0.0 1.9 1 0 0 1 1 1 0 HisG, C-terminal domain gag_pre-integrs PF13976.6 CDO76920.1 - 2.7e-07 30.4 0.4 4.9e-07 29.5 0.4 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 CDO76920.1 - 0.0078 16.4 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Kinesin PF00225.23 CDO76921.1 - 9.7e-92 307.4 0.0 1.3e-91 307.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CDO76921.1 - 1.8e-20 73.4 0.0 3e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Surfac_D-trimer PF09006.11 CDO76921.1 - 0.00072 19.4 0.2 0.0033 17.3 0.0 2.1 2 0 0 2 2 2 1 Lung surfactant protein D coiled-coil trimerisation DUF2866 PF11065.8 CDO76921.1 - 0.0068 16.4 4.6 0.094 12.7 0.1 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2866) EC042_2821 PF18740.1 CDO76921.1 - 0.094 12.6 0.1 0.56 10.1 0.0 2.3 3 0 0 3 3 3 0 EC042_2821-lke REase TPR_11 PF13414.6 CDO76921.1 - 0.11 12.2 1.3 0.26 11.0 0.3 2.0 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 CDO76921.1 - 0.14 12.3 0.4 0.38 11.0 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CENP-F_leu_zip PF10473.9 CDO76922.1 - 2.3e-05 24.4 13.0 2.3e-05 24.4 13.0 7.7 3 1 4 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 CDO76922.1 - 0.00012 21.1 80.5 0.0011 17.9 4.2 5.9 2 1 5 7 7 7 4 Spc7 kinetochore protein CALCOCO1 PF07888.11 CDO76922.1 - 0.0019 17.2 18.2 0.0019 17.2 18.2 4.5 2 1 2 4 4 3 2 Calcium binding and coiled-coil domain (CALCOCO1) like BST2 PF16716.5 CDO76922.1 - 0.006 17.1 0.8 0.006 17.1 0.8 8.5 3 3 7 10 10 10 2 Bone marrow stromal antigen 2 Fez1 PF06818.15 CDO76922.1 - 0.0067 16.9 78.1 0.023 15.2 10.7 6.1 3 1 2 5 5 5 2 Fez1 IFT57 PF10498.9 CDO76922.1 - 0.022 13.8 48.0 0.019 13.9 15.4 4.7 2 1 2 4 4 4 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 CDO76922.1 - 0.08 13.0 34.6 0.019 15.0 3.7 6.1 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) ADIP PF11559.8 CDO76922.1 - 0.1 12.7 0.1 0.1 12.7 0.1 7.8 4 1 4 8 8 8 0 Afadin- and alpha -actinin-Binding Sox17_18_mid PF12067.8 CDO76922.1 - 0.12 12.5 0.1 0.43 10.6 0.1 2.0 1 0 0 1 1 1 0 Sox 17/18 central domain CCDC144C PF14915.6 CDO76922.1 - 0.14 11.3 74.0 2 7.5 13.9 5.1 2 1 2 4 4 4 0 CCDC144C protein coiled-coil region Fib_alpha PF08702.10 CDO76922.1 - 0.39 10.9 32.8 0.21 11.8 4.6 6.2 4 2 3 8 8 8 0 Fibrinogen alpha/beta chain family DUF812 PF05667.11 CDO76922.1 - 0.8 8.5 62.9 0.59 9.0 0.7 4.7 2 1 2 4 4 4 0 Protein of unknown function (DUF812) DUF4201 PF13870.6 CDO76922.1 - 0.87 9.3 58.4 0.28 10.9 6.8 6.9 2 1 2 6 6 6 0 Domain of unknown function (DUF4201) HMMR_N PF15905.5 CDO76922.1 - 1.6 8.1 63.5 0.68 9.3 5.2 5.4 2 1 2 5 5 5 0 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 CDO76922.1 - 1.6 8.1 71.2 3.3 7.1 1.9 5.7 2 1 1 5 5 5 0 Golgin subfamily A member 5 FPP PF05911.11 CDO76922.1 - 2.3 6.3 63.3 1.4 7.0 13.3 4.8 2 1 3 5 5 5 0 Filament-like plant protein, long coiled-coil MAD PF05557.13 CDO76922.1 - 2.8 6.2 67.2 0.049 12.0 22.3 4.2 2 1 2 4 4 4 0 Mitotic checkpoint protein APG6_N PF17675.1 CDO76922.1 - 3 8.4 102.4 0.39 11.3 3.5 7.6 2 1 4 6 6 6 0 Apg6 coiled-coil region DUF5082 PF16888.5 CDO76922.1 - 3.5 7.9 29.2 0.33 11.2 3.2 5.9 3 1 2 5 5 5 0 Domain of unknown function (DUF5082) LSM PF01423.22 CDO76923.1 - 4.2e-20 71.2 1.0 5.5e-20 70.8 1.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CDO76923.1 - 0.002 18.2 0.1 0.0028 17.8 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain BPL_C PF02237.17 CDO76923.1 - 0.023 14.6 0.2 0.04 13.8 0.2 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Tail_tube PF10618.9 CDO76923.1 - 0.068 13.1 0.2 0.39 10.6 0.2 1.9 1 1 1 2 2 2 0 Phage tail tube protein Hfq PF17209.3 CDO76923.1 - 0.15 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Hfq protein API5 PF05918.11 CDO76923.1 - 3.4 6.4 6.6 4.7 5.9 6.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FoP_duplication PF13865.6 CDO76923.1 - 3.8 8.1 14.5 6.9 7.3 14.5 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Oxidored_FMN PF00724.20 CDO76924.1 - 3.4e-34 118.6 0.0 1.2e-32 113.6 0.0 2.2 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family 2-Hacid_dh PF00389.30 CDO76925.1 - 2.7e-18 65.9 0.0 3.7e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Melibiase_2 PF16499.5 CDO76926.1 - 3.3e-11 42.9 0.0 0.0034 16.6 0.0 4.3 5 0 0 5 5 5 3 Alpha galactosidase A Melibiase PF02065.18 CDO76926.1 - 0.088 11.7 0.0 1.4 7.8 0.0 2.0 2 0 0 2 2 2 0 Melibiase RCC1 PF00415.18 CDO76928.1 - 2.9e-56 187.9 10.9 5.2e-11 43.0 0.0 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDO76928.1 - 4.3e-40 134.7 28.1 4.4e-09 35.9 0.4 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat HCNGP PF07818.13 CDO76929.1 - 2.2e-34 118.0 0.3 2.2e-34 118.0 0.3 1.8 2 0 0 2 2 2 1 HCNGP-like protein DUF3663 PF12404.8 CDO76930.1 - 0.015 15.3 0.2 0.056 13.5 0.1 2.0 2 0 0 2 2 2 0 Peptidase Zn_clus PF00172.18 CDO76931.1 - 0.00022 21.3 3.8 0.00022 21.3 3.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1179 PF06678.11 CDO76931.1 - 0.031 14.3 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Mcp5_PH PF12814.7 CDO76932.1 - 1.9e-45 153.9 0.2 3.5e-45 153.1 0.2 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology ATG16 PF08614.11 CDO76932.1 - 1.9e-05 25.0 16.3 1.9e-05 25.0 16.3 5.0 4 1 1 5 5 5 2 Autophagy protein 16 (ATG16) PH PF00169.29 CDO76932.1 - 6.8e-05 23.3 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 PH domain MAD PF05557.13 CDO76932.1 - 0.011 14.1 38.5 0.026 12.9 24.9 3.1 3 0 0 3 3 3 0 Mitotic checkpoint protein Macoilin PF09726.9 CDO76932.1 - 0.72 8.3 26.2 0.77 8.2 23.4 2.3 2 0 0 2 2 2 0 Macoilin family RPW8 PF05659.11 CDO76932.1 - 1.9 8.2 5.3 13 5.5 1.0 2.7 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spc7 PF08317.11 CDO76932.1 - 5.3 5.8 39.0 0.36 9.7 24.2 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein WD40 PF00400.32 CDO76934.1 - 3.9e-54 179.4 19.2 2.9e-08 34.2 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CDO76934.1 - 1.5e-27 95.7 5.2 2.6e-27 94.9 5.2 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CDO76934.1 - 5.1e-20 71.6 0.2 2.3e-05 24.6 0.0 6.2 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CDO76934.1 - 1.3e-09 37.8 0.0 0.012 14.9 0.0 4.7 4 2 2 6 6 6 2 WD40-like domain Ge1_WD40 PF16529.5 CDO76934.1 - 3.2e-08 32.9 0.4 0.59 9.0 0.0 5.4 2 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CDO76934.1 - 0.00026 19.7 1.4 0.009 14.6 0.2 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nbas_N PF15492.6 CDO76934.1 - 0.0012 18.2 0.0 11 5.2 0.0 3.4 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 CDO76934.1 - 0.0023 17.8 0.1 17 5.5 0.0 5.0 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 CDO76934.1 - 0.008 15.3 0.1 0.67 8.9 0.0 3.0 2 1 1 3 3 3 1 VID27 C-terminal WD40-like domain Nup160 PF11715.8 CDO76934.1 - 0.055 12.1 1.0 1.2 7.7 0.0 3.3 2 1 3 5 5 5 0 Nucleoporin Nup120/160 Frtz PF11768.8 CDO76934.1 - 0.078 11.3 0.0 5.9 5.1 0.0 2.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz V-SNARE PF05008.15 CDO76934.1 - 0.089 13.2 3.4 0.17 12.3 3.4 1.5 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus BRE1 PF08647.11 CDO76934.1 - 0.098 12.7 1.3 0.24 11.5 1.3 1.7 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase RAB3GAP2_N PF14655.6 CDO76934.1 - 0.12 11.6 0.0 0.61 9.3 0.0 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF5122 PF17164.4 CDO76934.1 - 0.12 12.7 2.4 57 4.1 0.0 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller Coagulase PF08764.10 CDO76934.1 - 0.14 12.3 0.2 0.22 11.7 0.2 1.2 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Proteasome_A_N PF10584.9 CDO76934.1 - 0.83 9.4 3.8 1.4e+02 2.3 0.0 4.7 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PRP38_assoc PF12871.7 CDO76934.1 - 2.3 8.8 57.3 2 9.0 31.8 2.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Spc7 PF08317.11 CDO76934.1 - 2.4 6.9 9.9 0.067 12.1 1.8 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein MFS_1 PF07690.16 CDO76935.1 - 1.1e-28 100.2 51.1 1.1e-26 93.6 51.9 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO76935.1 - 9.2e-22 77.2 15.3 1.7e-21 76.3 15.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CDO76935.1 - 8.9e-07 28.1 11.7 8.9e-07 28.1 11.7 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO76936.1 - 3e-15 56.0 28.9 4.1e-11 42.4 15.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily p450 PF00067.22 CDO76937.1 - 1.3e-54 185.7 0.0 3.2e-54 184.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Plavaka PF18759.1 CDO76939.1 - 2.3e-124 414.8 0.0 3.4e-124 414.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-Di19 PF05605.12 CDO76939.1 - 2.3 8.6 5.5 0.25 11.6 0.2 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 CDO76939.1 - 2.6 7.9 4.2 0.67 9.8 0.1 2.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) NAD_kinase PF01513.21 CDO76941.1 - 1.8e-27 96.3 0.0 3.6e-26 92.0 0.0 2.0 1 1 1 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.24 CDO76941.1 - 0.074 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain XPG_I_2 PF12813.7 CDO76942.1 - 4.6e-07 29.6 0.0 0.00011 21.8 0.0 3.9 4 1 0 4 4 4 1 XPG domain containing PH PF00169.29 CDO76943.1 - 0.0003 21.3 0.0 0.00058 20.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PB1 PF00564.24 CDO76945.1 - 1.2e-11 44.3 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.17 CDO76945.1 - 0.00015 21.6 4.2 0.59 10.4 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDO76945.1 - 0.0059 16.4 6.3 2.1 8.3 0.0 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat Paf67 PF10255.9 CDO76945.1 - 0.0088 15.1 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 PolyA_pol_arg_C PF12626.7 CDO76946.1 - 0.09 12.8 0.6 0.13 12.3 0.6 1.3 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus Ribosomal_L37 PF08561.10 CDO76947.1 - 1.5e-16 61.0 6.0 8.5e-14 52.1 0.1 2.6 3 0 0 3 3 3 2 Mitochondrial ribosomal protein L37 zf-C3HC4_3 PF13920.6 CDO76949.1 - 4.7e-07 29.6 6.8 4.7e-07 29.6 6.8 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-H2C2_5 PF13909.6 CDO76949.1 - 0.0031 17.2 0.1 0.12 12.1 0.0 2.9 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C3HC4 PF00097.25 CDO76949.1 - 0.014 15.3 8.8 0.014 15.3 8.8 3.5 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 CDO76949.1 - 0.079 13.8 1.4 0.079 13.8 1.4 4.3 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDO76949.1 - 0.79 10.3 0.0 0.79 10.3 0.0 4.9 6 0 0 6 6 6 0 Zinc finger, C2H2 type FoP_duplication PF13865.6 CDO76949.1 - 1.6 9.3 11.0 3.1 8.4 11.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-RING_2 PF13639.6 CDO76949.1 - 4.5 7.7 24.2 1.2 9.5 9.7 2.9 3 0 0 3 3 3 0 Ring finger domain ADH_zinc_N PF00107.26 CDO76951.1 - 4.7e-15 55.7 0.0 7.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO76951.1 - 2.5e-07 31.8 0.0 4.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO76951.1 - 2.2e-05 24.3 0.6 0.00014 21.7 0.5 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Plant_vir_prot PF01307.17 CDO76951.1 - 0.02 15.1 0.0 0.054 13.7 0.0 1.7 2 0 0 2 2 2 0 Plant viral movement protein Sulfotransfer_4 PF17784.1 CDO76952.1 - 0.017 14.9 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase domain LPD34 PF18852.1 CDO76953.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 DUF5122 PF17164.4 CDO76955.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller DDE_Tnp_4 PF13359.6 CDO76956.1 - 2.1e-17 63.2 0.0 2.6e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO76956.1 - 1.6e-06 27.9 0.0 4.9e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO76956.1 - 0.0062 16.2 0.1 0.01 15.5 0.1 1.5 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO76956.1 - 0.043 14.2 0.2 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Transposase DDE domain MMS1_N PF10433.9 CDO76960.1 - 1e-158 529.1 0.0 1.4e-158 528.5 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CDO76960.1 - 1.8e-94 316.7 0.1 6.3e-94 314.9 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region Topoisom_bac PF01131.20 CDO76960.1 - 1.2e-86 291.4 0.0 1.3e-52 179.2 0.0 2.3 1 1 1 2 2 2 2 DNA topoisomerase Toprim PF01751.22 CDO76960.1 - 2.8e-20 72.5 0.0 1.2e-19 70.4 0.0 2.2 2 0 0 2 2 2 1 Toprim domain zf-GRF PF06839.12 CDO76960.1 - 2.2e-16 59.7 11.8 5.2e-10 39.2 4.3 2.6 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC PF00098.23 CDO76960.1 - 5.1e-09 35.8 12.5 2.1e-05 24.3 2.4 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CDO76960.1 - 0.00088 19.2 2.9 0.14 12.1 0.5 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 CDO76960.1 - 0.004 17.0 0.9 0.004 17.0 0.9 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 CDO76960.1 - 0.073 12.8 3.7 0.087 12.5 1.3 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger p450 PF00067.22 CDO76961.1 - 1.7e-68 231.4 0.0 2.1e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1297 PF06973.12 CDO76961.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) Glyoxal_oxid_N PF07250.11 CDO76962.1 - 5.5e-28 97.8 0.3 4.5e-25 88.2 0.3 3.4 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CDO76962.1 - 3.8e-24 84.8 0.1 7.1e-24 83.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 CDO76962.1 - 0.00049 20.1 1.0 0.14 12.2 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain AFG1_ATPase PF03969.16 CDO76964.1 - 2e-29 102.7 0.0 6.6e-24 84.5 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase RHD3 PF05879.12 CDO76965.1 - 7.3e-248 824.5 2.6 4.3e-247 822.0 2.6 1.8 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 CDO76965.1 - 4.7e-07 29.3 0.1 1e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 CDO76965.1 - 8.7e-07 29.0 0.0 2.6e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CDO76965.1 - 1.7e-05 25.0 0.0 3.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 CDO76965.1 - 0.00081 19.7 0.0 0.0026 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 CDO76965.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 CDO76965.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 CDO76965.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase BTB PF00651.31 CDO76966.1 - 3.7e-07 30.4 0.0 7.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain HAD_2 PF13419.6 CDO76967.1 - 3.6e-18 66.3 0.0 6.9e-18 65.4 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CDO76967.1 - 1.9e-11 44.7 0.0 1.4e-10 41.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDO76967.1 - 4.1e-05 24.1 0.0 6.5e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CDO76967.1 - 0.001 19.1 0.0 0.48 10.6 0.0 2.7 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CDO76967.1 - 0.056 13.5 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 HAD-hyrolase-like PAP2_3 PF14378.6 CDO76968.1 - 0.041 13.6 0.1 0.058 13.1 0.1 1.2 1 0 0 1 1 1 0 PAP2 superfamily BTB PF00651.31 CDO76970.1 - 7e-10 39.1 0.3 9.4e-10 38.7 0.3 1.2 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.6 CDO76971.1 - 4.9e-14 51.9 0.0 4.5e-05 23.3 0.0 4.9 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.6 CDO76971.1 - 4.9e-14 52.1 0.1 2.4e-06 27.5 0.0 5.1 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CDO76971.1 - 1.8e-07 31.2 0.8 0.12 12.7 0.0 5.5 5 1 1 6 6 6 2 Kelch motif Kelch_3 PF13415.6 CDO76971.1 - 5e-07 29.9 1.2 0.47 10.8 0.0 6.1 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CDO76971.1 - 3.8e-05 23.2 0.3 3.9 7.2 0.1 4.1 3 1 0 3 3 3 2 Kelch motif Prefoldin_2 PF01920.20 CDO76972.1 - 2.7e-23 81.9 4.4 3.1e-23 81.7 4.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit PI3K_P85_iSH2 PF16454.5 CDO76972.1 - 0.0036 16.9 4.2 0.2 11.3 0.4 2.1 2 0 0 2 2 2 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain V_ATPase_I PF01496.19 CDO76972.1 - 0.0049 14.9 0.9 0.0064 14.5 0.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family FPP PF05911.11 CDO76972.1 - 0.0064 14.7 3.4 0.0083 14.4 3.4 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Prefoldin PF02996.17 CDO76972.1 - 0.0076 16.1 6.7 0.24 11.3 0.4 2.1 1 1 1 2 2 2 2 Prefoldin subunit NPV_P10 PF05531.12 CDO76972.1 - 0.015 15.7 1.4 2.4 8.7 0.6 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc24 PF08286.11 CDO76972.1 - 0.025 14.8 4.8 1.9 8.8 0.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 BLOC1_2 PF10046.9 CDO76972.1 - 0.027 14.8 6.0 0.087 13.1 1.4 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran_CTD PF16326.5 CDO76972.1 - 0.04 14.2 8.1 0.85 9.9 1.6 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Helo_like_N PF17111.5 CDO76972.1 - 0.048 13.0 5.6 0.52 9.6 1.1 2.0 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins PspA_IM30 PF04012.12 CDO76972.1 - 0.067 12.8 6.1 0.37 10.3 0.2 2.1 2 0 0 2 2 2 0 PspA/IM30 family DivIC PF04977.15 CDO76972.1 - 0.095 12.5 11.4 0.83 9.5 1.9 2.2 1 1 1 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.9 CDO76972.1 - 0.16 12.0 9.8 0.89 9.6 1.9 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.6 CDO76972.1 - 0.18 12.3 7.9 3.1 8.3 0.8 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DASH_Dad4 PF08650.10 CDO76972.1 - 0.21 11.5 3.2 6.1 6.9 0.2 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 DUF16 PF01519.16 CDO76972.1 - 0.36 11.3 5.6 55 4.3 5.6 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 PCRF PF03462.18 CDO76972.1 - 0.4 10.5 5.1 0.66 9.8 5.1 1.3 1 1 0 1 1 1 0 PCRF domain Swi5 PF07061.11 CDO76972.1 - 0.41 10.8 4.9 7.8 6.7 0.6 2.2 2 0 0 2 2 2 0 Swi5 XhlA PF10779.9 CDO76972.1 - 0.43 10.8 6.5 6.1 7.1 1.1 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DASH_Dam1 PF08653.10 CDO76972.1 - 0.54 10.1 2.7 0.48 10.2 0.6 1.9 2 1 0 2 2 2 0 DASH complex subunit Dam1 MCC-bdg_PDZ PF10506.9 CDO76972.1 - 0.61 10.1 6.4 0.8 9.8 1.1 2.2 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome SlyX PF04102.12 CDO76972.1 - 0.97 10.1 6.1 8.3 7.1 0.4 2.3 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.11 CDO76972.1 - 0.97 9.9 7.6 4.2 7.8 0.7 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FapA PF03961.13 CDO76972.1 - 1.3 7.5 4.9 2.6 6.6 4.9 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 CDO76972.1 - 1.8 7.4 9.5 5.3 5.8 9.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Med21 PF11221.8 CDO76972.1 - 2.5 8.4 8.5 4.8 7.4 1.7 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex bZIP_1 PF00170.21 CDO76972.1 - 6.8 6.9 11.3 5.9 7.1 1.1 2.2 2 0 0 2 2 2 0 bZIP transcription factor EB1 PF03271.17 CDO76972.1 - 7.3 6.9 6.5 1.3e+02 3.0 6.5 2.4 1 1 0 1 1 1 0 EB1-like C-terminal motif Pyridoxal_deC PF00282.19 CDO76973.1 - 1.2e-14 53.8 0.0 2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CDO76973.1 - 1.2e-07 31.0 0.1 1.1e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CDO76973.1 - 3.3e-06 26.7 0.3 5.2e-06 26.0 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF436 PF04260.12 CDO76973.1 - 0.094 12.3 0.2 0.22 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF436) Sugar_tr PF00083.24 CDO76976.1 - 4.8e-51 174.0 16.9 8.3e-51 173.2 16.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO76976.1 - 3.1e-19 69.1 22.5 3.1e-19 69.1 22.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Plavaka PF18759.1 CDO76977.1 - 5.4e-21 75.1 0.0 1.1e-13 51.1 0.0 2.4 1 1 1 2 2 2 2 Plavaka transposase BNIP3 PF06553.12 CDO76977.1 - 0.17 11.5 0.3 0.36 10.5 0.3 1.4 1 0 0 1 1 1 0 BNIP3 Sugar_tr PF00083.24 CDO76979.1 - 1.4e-49 169.2 17.6 3.9e-49 167.7 17.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO76979.1 - 5.2e-14 51.9 33.0 5.2e-14 51.9 33.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MASE3 PF17159.4 CDO76979.1 - 0.0077 15.9 1.7 0.033 13.8 0.2 2.4 2 0 0 2 2 2 1 Membrane-associated sensor domain Tubulin PF00091.25 CDO76984.1 - 2.2e-37 129.2 0.0 1.8e-36 126.2 0.0 2.1 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CDO76984.1 - 4.8e-37 126.9 0.0 8.4e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CDO76984.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Methyltransf_2 PF00891.18 CDO76984.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Tubulin_2 PF13809.6 CDO76984.1 - 0.15 11.2 0.0 0.35 10.0 0.0 1.5 2 0 0 2 2 2 0 Tubulin like DUF1479 PF07350.12 CDO76985.1 - 3.9e-137 457.4 0.0 4.6e-137 457.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 CDO76985.1 - 2.7e-05 24.5 0.0 0.054 13.7 0.0 2.7 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Cyanate_lyase PF02560.14 CDO76986.1 - 5.4e-26 90.2 0.0 1e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Complex1_LYR_2 PF13233.6 CDO76986.1 - 8.1e-11 42.5 0.0 1.3e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CDO76986.1 - 5e-05 23.3 0.0 9.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4604 PF15377.6 CDO76987.1 - 8e-30 104.5 15.9 2.5e-29 102.9 15.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Peptidase_S10 PF00450.22 CDO76988.1 - 2.1e-63 215.2 0.1 1.9e-62 212.0 0.1 2.3 1 1 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 CDO76988.1 - 0.01 15.1 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 CIA30 PF08547.12 CDO76991.1 - 1.2e-20 74.1 0.0 1.4e-18 67.5 0.0 2.2 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 CDO76991.1 - 0.045 13.7 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain CBM_11 PF03425.13 CDO76991.1 - 0.11 12.4 0.0 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate binding domain (family 11) Ras PF00071.22 CDO76993.1 - 2.1e-56 190.0 0.0 2.5e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CDO76993.1 - 1.3e-20 73.8 0.0 2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CDO76993.1 - 2e-09 37.1 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CDO76993.1 - 1.1e-05 25.1 0.0 3e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CDO76993.1 - 0.00014 21.8 0.0 0.27 11.1 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CDO76993.1 - 0.0026 17.8 0.0 0.0045 17.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CDO76993.1 - 0.29 10.9 1.8 2.6 7.8 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_B PF00430.18 CDO76994.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2240 PF09999.9 CDO76994.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) IMS PF00817.20 CDO76995.1 - 2.5e-33 115.2 0.0 5.1e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CDO76995.1 - 6.4e-15 55.9 0.0 5e-14 53.0 0.0 2.4 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 CDO76995.1 - 0.00029 20.3 3.3 0.012 15.2 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Get5_bdg PF16843.5 CDO76995.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein NUDIX PF00293.28 CDO76996.1 - 2.9e-11 43.5 0.0 5.5e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain TauD PF02668.16 CDO76998.1 - 1.9e-32 113.1 0.0 2.6e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CAS_CSE1 PF03378.15 CDO76999.1 - 8.4e-123 410.1 0.6 1.2e-122 409.6 0.6 1.2 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 CDO76999.1 - 6.1e-82 275.4 0.0 2.8e-75 253.5 0.0 2.6 2 1 1 3 3 3 2 Cse1 IBN_N PF03810.19 CDO76999.1 - 7.8e-15 54.6 0.1 4.1e-14 52.2 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CDO76999.1 - 0.0036 17.7 6.8 0.19 12.1 0.2 3.9 3 1 1 4 4 4 2 HEAT repeats Xpo1 PF08389.12 CDO76999.1 - 0.02 15.0 0.1 0.41 10.7 0.0 3.2 4 0 0 4 4 4 0 Exportin 1-like protein HEAT PF02985.22 CDO76999.1 - 0.21 11.9 12.8 0.74 10.2 0.1 5.8 7 0 0 7 7 7 0 HEAT repeat Hydrophobin PF01185.18 CDO77000.1 - 2.1e-22 79.6 8.0 2.7e-22 79.2 8.0 1.2 1 0 0 1 1 1 1 Fungal hydrophobin MFS_1 PF07690.16 CDO77001.1 - 3.6e-40 138.0 25.4 5.2e-40 137.4 25.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO77001.1 - 2.7e-11 43.0 4.6 2.7e-11 43.0 4.6 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CDO77001.1 - 0.00044 18.8 1.3 0.00066 18.2 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YbgT_YccB PF08173.11 CDO77001.1 - 0.0015 18.6 1.6 0.0043 17.2 0.1 2.6 2 0 0 2 2 2 1 Membrane bound YbgT-like protein Sde2_N_Ubi PF13019.6 CDO77002.1 - 1e-52 178.2 1.2 1.2e-52 178.0 0.0 1.7 2 1 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain DUF1295 PF06966.12 CDO77003.1 - 3.7e-35 121.5 3.2 3.7e-35 121.5 3.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.14 CDO77003.1 - 0.028 14.8 0.0 0.097 13.1 0.0 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family zf-C2H2 PF00096.26 CDO77004.1 - 2e-06 27.9 1.7 0.093 13.2 0.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO77004.1 - 5.4e-05 23.7 2.5 0.19 12.7 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CDO77004.1 - 7.3e-05 22.4 2.6 0.0005 19.8 0.3 2.8 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-BED PF02892.15 CDO77004.1 - 0.12 12.4 2.3 2.7 8.1 0.2 2.7 2 1 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 CDO77006.1 - 1.3e-06 28.5 2.8 0.046 14.2 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CDO77006.1 - 1.6e-05 24.6 6.6 0.00012 21.8 1.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 CDO77006.1 - 3.1e-05 24.4 2.7 0.22 12.5 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 CDO77006.1 - 0.13 12.7 0.1 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 CDO77006.1 - 0.18 11.8 1.0 9.5 6.3 0.0 2.8 2 1 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 CDO77006.1 - 6.1 7.5 13.8 4.2 8.0 2.4 3.7 4 0 0 4 4 4 0 Zinc-finger double domain MFS_1 PF07690.16 CDO77007.1 - 7.5e-25 87.6 21.7 7.5e-25 87.6 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO77007.1 - 1.6e-09 37.2 15.7 3e-05 23.1 4.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 CDO77007.1 - 4.4e-05 22.2 4.1 4.4e-05 22.2 4.1 3.1 2 2 1 3 3 3 1 MFS/sugar transport protein Proton_antipo_N PF00662.20 CDO77007.1 - 0.024 14.7 0.2 0.061 13.4 0.2 1.7 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus IlvN PF07991.12 CDO77008.1 - 4.1e-46 156.6 0.0 8.4e-46 155.6 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 CDO77008.1 - 6.1e-38 130.3 0.0 9.5e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ThuA PF06283.11 CDO77009.1 - 2.5e-56 191.2 0.0 3.5e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 Trehalose utilisation Pro-kuma_activ PF09286.11 CDO77010.1 - 2.4e-44 151.1 0.0 6e-44 149.8 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO77010.1 - 0.00067 19.0 1.6 0.0011 18.3 1.6 1.2 1 0 0 1 1 1 1 Subtilase family Pyr_redox_2 PF07992.14 CDO77011.1 - 1.8e-48 165.3 2.1 2.5e-48 164.8 2.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 CDO77011.1 - 1.4e-18 66.6 0.2 3.9e-18 65.2 0.1 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.6 CDO77011.1 - 1.1e-08 34.7 1.0 1.9e-08 33.9 0.3 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 CDO77011.1 - 2.5e-08 34.3 0.0 6.3e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal Pyr_redox PF00070.27 CDO77011.1 - 1.1e-07 32.3 5.4 6.8e-07 29.8 0.1 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CDO77011.1 - 1.2e-06 27.9 1.0 0.21 10.7 0.0 3.1 2 1 1 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Rieske_2 PF13806.6 CDO77011.1 - 3.3e-06 27.0 0.0 1.3e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_7 PF13241.6 CDO77011.1 - 0.011 16.2 0.1 0.11 13.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding HET PF06985.11 CDO77012.1 - 2e-10 41.2 9.4 5.5e-08 33.3 2.6 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 CDO77013.1 - 1.5e-14 54.5 7.4 1.2e-12 48.4 0.9 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) PI3Ka PF00613.20 CDO77014.1 - 2e-57 193.6 0.5 3.7e-57 192.7 0.5 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CDO77014.1 - 9.6e-43 146.8 0.0 1.2e-26 94.0 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CDO77014.1 - 2.2e-33 115.1 0.0 1.6e-32 112.3 0.0 2.1 1 1 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 CDO77014.1 - 0.016 15.5 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 C2 domain Aminotran_3 PF00202.21 CDO77015.1 - 1.4e-21 76.7 0.0 2.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 CDO77015.1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.26 CDO77016.1 - 1.6e-17 63.5 0.0 2.6e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme STIMATE PF12400.8 CDO77017.1 - 4.1e-37 127.5 7.1 7.1e-37 126.7 7.1 1.4 1 0 0 1 1 1 1 STIMATE family SR-25 PF10500.9 CDO77017.1 - 1.3 8.5 12.8 2 8.0 12.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ndc1_Nup PF09531.10 CDO77017.1 - 2.5 6.7 5.3 5.9 5.5 5.3 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Uds1 PF15456.6 CDO77018.1 - 2e-34 118.5 9.2 2e-34 118.5 9.2 6.6 3 2 2 5 5 5 1 Up-regulated During Septation PKcGMP_CC PF16808.5 CDO77018.1 - 0.024 14.5 1.2 0.024 14.5 1.2 5.1 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RTP PF02334.16 CDO77018.1 - 0.042 14.5 2.0 3.3 8.4 0.1 2.8 2 0 0 2 2 2 0 Replication terminator protein Filament PF00038.21 CDO77018.1 - 1.8 8.1 82.9 0.37 10.3 8.3 6.2 4 2 2 6 6 6 0 Intermediate filament protein Arm_APC_u3 PF16629.5 CDO77018.1 - 2.8 7.5 10.5 5.2 6.6 2.2 3.0 2 1 0 2 2 2 0 Armadillo-associated region on APC Tho1_MOS11_C PF18592.1 CDO77018.1 - 5.2 7.0 10.2 0.24 11.2 1.5 3.3 3 0 0 3 3 3 0 Tho1/MOS11 C-terminal domain DUF4407 PF14362.6 CDO77018.1 - 5.8 6.2 72.9 0.3 10.4 13.9 4.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4407) CorA PF01544.18 CDO77019.1 - 2.1e-45 155.3 0.5 3.1e-45 154.7 0.5 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 CDO77019.1 - 0.032 14.3 0.5 0.07 13.2 0.5 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PLU-1 PF08429.11 CDO77020.1 - 2.6e-52 178.1 0.5 2.6e-52 178.1 0.5 2.2 2 1 0 2 2 2 1 PLU-1-like protein JmjC PF02373.22 CDO77020.1 - 1.6e-41 141.3 0.7 4.6e-41 139.8 0.4 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 CDO77020.1 - 3.8e-16 59.2 9.6 3.8e-16 59.2 9.6 2.6 3 0 0 3 3 3 1 C5HC2 zinc finger JmjN PF02375.17 CDO77020.1 - 9.1e-16 57.5 0.4 2e-15 56.4 0.4 1.7 1 0 0 1 1 1 1 jmjN domain ARID PF01388.21 CDO77020.1 - 1e-10 42.1 0.0 3.4e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 CDO77020.1 - 3.4e-10 39.7 47.4 1.8e-08 34.2 7.6 5.0 5 0 0 5 5 5 3 PHD-finger 14-3-3 PF00244.20 CDO77021.1 - 2.9e-107 357.3 4.0 3.3e-107 357.1 4.0 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 CDO77021.1 - 0.098 11.0 3.0 0.16 10.4 3.0 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 TPR_19 PF14559.6 CDO77021.1 - 0.48 11.0 3.3 0.63 10.6 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C PF00271.31 CDO77023.1 - 0.00093 19.5 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC_6 PF15288.6 CDO77023.1 - 0.12 12.3 0.3 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 Zinc knuckle Rrn6 PF10214.9 CDO77023.1 - 0.83 8.1 3.4 1.1 7.7 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_S28 PF05577.12 CDO77024.1 - 8.9e-51 173.0 0.7 3.7e-36 124.8 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 CDO77024.1 - 0.0072 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 CDO77024.1 - 0.079 11.6 0.4 0.19 10.4 0.0 1.7 2 0 0 2 2 2 0 PS-10 peptidase S37 RRM_1 PF00076.22 CDO77027.1 - 1.4e-08 34.4 0.0 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDO77027.1 - 0.026 14.5 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Adeno_E3_CR2 PF02439.15 CDO77028.1 - 0.00023 20.9 1.6 0.00038 20.2 1.6 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 CDO77028.1 - 0.00064 19.1 1.3 0.0011 18.3 1.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DAP10 PF07213.11 CDO77028.1 - 0.15 12.0 1.5 0.3 11.1 1.5 1.4 1 0 0 1 1 1 0 DAP10 membrane protein YjbE PF11106.8 CDO77028.1 - 3.5 7.9 13.0 8.4 6.7 13.0 1.5 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE BcrAD_BadFG PF01869.20 CDO77029.1 - 4.1e-10 39.6 0.0 8.4e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 CDO77029.1 - 0.28 10.7 0.0 0.45 10.0 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Cupin_1 PF00190.22 CDO77030.1 - 4e-36 123.9 0.2 7e-19 67.9 0.2 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CDO77030.1 - 1.2e-25 89.0 0.2 7.7e-15 54.4 0.1 2.6 2 1 0 2 2 2 2 Cupin domain MannoseP_isomer PF01050.18 CDO77030.1 - 2.3e-06 27.6 0.0 6.2e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.12 CDO77030.1 - 5.9e-06 25.9 0.0 0.0064 16.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 CDO77030.1 - 7.8e-05 22.6 1.2 0.32 10.9 0.0 2.8 2 1 0 2 2 2 2 AraC-like ligand binding domain Cupin_4 PF08007.12 CDO77030.1 - 8.2e-05 22.2 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_8 PF13621.6 CDO77030.1 - 0.0074 16.0 0.0 0.45 10.2 0.0 2.3 2 0 0 2 2 2 1 Cupin-like domain ARD PF03079.14 CDO77030.1 - 0.11 12.7 0.1 1.4 9.1 0.0 2.1 2 0 0 2 2 2 0 ARD/ARD' family Cupin_2 PF07883.11 CDO77031.1 - 4.9e-08 32.6 0.3 9e-08 31.7 0.3 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CDO77031.1 - 0.00037 20.4 0.3 0.00049 20.0 0.3 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 CDO77031.1 - 0.00049 19.9 0.2 0.00058 19.6 0.2 1.1 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.22 CDO77031.1 - 0.0019 17.9 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Ppnp PF06865.11 CDO77031.1 - 0.23 11.9 0.0 0.35 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine/purine nucleoside phosphorylase MFS_1 PF07690.16 CDO77032.1 - 8.3e-30 103.9 30.5 8.9e-30 103.8 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 CDO77033.1 - 1.6e-51 174.2 0.0 2.1e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CDO77033.1 - 5.9e-19 68.1 0.0 8.7e-19 67.5 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CDO77033.1 - 0.00072 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 CDO77033.1 - 0.0091 15.3 0.5 0.032 13.5 0.5 1.9 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 CDO77033.1 - 0.029 14.9 0.1 0.081 13.4 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain IlvN PF07991.12 CDO77033.1 - 0.045 13.3 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F-box-like PF12937.7 CDO77034.1 - 0.0001 22.1 0.4 0.0001 22.1 0.4 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDO77034.1 - 0.00093 19.0 1.8 0.00093 19.0 1.8 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CDO77035.1 - 6.3e-08 32.4 0.2 1.5e-07 31.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO77035.1 - 1.4e-05 24.8 0.9 3.4e-05 23.6 0.9 1.6 1 0 0 1 1 1 1 F-box domain Ank_4 PF13637.6 CDO77036.1 - 0.00011 22.7 0.2 0.01 16.4 0.0 3.9 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Dimer_Tnp_hAT PF05699.14 CDO77036.1 - 0.00059 19.6 6.1 0.76 9.6 0.0 4.9 4 1 1 5 5 5 3 hAT family C-terminal dimerisation region SAP PF02037.27 CDO77036.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 SAP domain Sel1 PF08238.12 CDO77037.1 - 3.8e-19 68.7 41.3 3.9e-05 24.2 0.5 10.1 9 2 0 9 9 9 7 Sel1 repeat TPR_10 PF13374.6 CDO77037.1 - 0.00056 19.7 1.5 0.28 11.1 0.2 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CDO77037.1 - 0.0046 17.6 2.0 0.0046 17.6 2.0 5.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CDO77037.1 - 0.024 14.7 0.4 0.024 14.7 0.4 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 CDO77037.1 - 0.065 13.5 6.8 0.18 12.1 0.5 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CDO77037.1 - 1.7 9.7 5.3 2.5 9.2 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDO77037.1 - 3.7 8.0 6.5 0.73 10.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CDO77037.1 - 4 8.3 13.4 38 5.2 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Helicase_C PF00271.31 CDO77038.1 - 0.00026 21.3 0.0 0.00053 20.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PPTA PF01239.22 CDO77039.1 - 1.5e-07 30.9 17.5 2.6e-06 26.9 0.1 4.6 6 0 0 6 6 6 2 Protein prenyltransferase alpha subunit repeat ASFV_J13L PF05568.11 CDO77041.1 - 0.2 11.4 3.4 0.39 10.5 3.4 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Plavaka PF18759.1 CDO77042.1 - 1.6e-127 425.3 0.0 2e-127 424.9 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase SWIB PF02201.18 CDO77043.1 - 5.7e-29 99.8 1.3 1.4e-28 98.6 1.3 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 CDO77043.1 - 5.3e-05 23.1 2.7 0.0002 21.2 1.2 2.6 3 1 0 3 3 3 1 DEK C terminal domain DUF1542 PF07564.11 CDO77043.1 - 0.11 12.6 2.0 0.18 11.9 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Glypican PF01153.19 CDO77043.1 - 0.28 10.0 3.3 0.39 9.5 3.3 1.2 1 0 0 1 1 1 0 Glypican SRP-alpha_N PF04086.13 CDO77043.1 - 0.86 9.5 11.4 1.2 9.0 11.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Spt5_N PF11942.8 CDO77043.1 - 1.4 9.9 7.0 0.41 11.7 3.6 1.9 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SdpI PF13630.6 CDO77044.1 - 0.77 9.9 15.6 1.2 9.3 0.6 3.7 3 1 1 4 4 4 0 SdpI/YhfL protein family RNase_T PF00929.24 CDO77045.1 - 2.3e-19 70.5 0.0 2.6e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Fcf1 PF04900.12 CDO77047.1 - 2.5e-39 133.7 2.3 4.1e-39 133.0 2.3 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CDO77047.1 - 2.7e-12 47.0 0.5 3.5e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 PIN like domain Lyase_aromatic PF00221.19 CDO77048.1 - 2e-151 504.8 4.5 2.6e-151 504.4 4.5 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase CPSase_L_D2 PF02786.17 CDO77049.1 - 6.2e-108 359.1 0.0 3.9e-83 278.1 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 CDO77049.1 - 1.2e-39 135.4 0.7 2.8e-39 134.2 0.7 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CDO77049.1 - 4.2e-16 59.0 0.0 5.6e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CDO77049.1 - 8.2e-12 45.1 0.0 3.4e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CDO77049.1 - 1.2e-09 38.0 0.0 0.0022 17.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 CDO77049.1 - 1.1e-06 28.2 0.0 0.0073 15.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 CDO77049.1 - 0.0011 18.6 0.0 1.4 8.5 0.0 3.0 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 CDO77049.1 - 0.0064 16.6 0.0 0.071 13.2 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.22 CDO77049.1 - 0.097 12.9 0.0 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 MGS-like domain Collagen_mid PF15984.5 CDO77049.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial collagen, middle region Epimerase PF01370.21 CDO77049.1 - 0.15 11.5 0.0 1.1 8.6 0.0 2.4 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family DAO PF01266.24 CDO77050.1 - 1.9e-43 149.4 0.0 2.3e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 CDO77050.1 - 1.3e-08 34.6 0.0 2.5e-05 23.8 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 CDO77050.1 - 1e-07 31.5 0.0 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CDO77050.1 - 4.1e-06 27.3 0.0 0.00082 19.9 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CDO77050.1 - 5.3e-06 26.6 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDO77050.1 - 0.00026 20.2 0.0 0.0059 15.7 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CDO77050.1 - 0.0016 17.6 0.0 0.42 9.7 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Shikimate_DH PF01488.20 CDO77050.1 - 0.0027 17.8 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 CDO77050.1 - 0.0029 16.4 0.0 0.74 8.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 CDO77050.1 - 0.01 15.9 0.0 0.73 9.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.18 CDO77050.1 - 0.014 15.6 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 CDO77050.1 - 0.015 14.5 0.1 0.05 12.8 0.0 1.8 2 1 1 3 3 3 0 Thi4 family Glu_dehyd_C PF16912.5 CDO77050.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 CDO77050.1 - 0.024 13.9 0.0 0.073 12.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CDO77050.1 - 0.033 14.6 0.0 0.065 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CDO77050.1 - 0.035 13.3 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 CDO77050.1 - 0.048 12.5 0.0 3.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 CDO77050.1 - 0.057 12.6 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Sacchrp_dh_NADP PF03435.18 CDO77050.1 - 0.066 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 CDO77050.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CDO77050.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CDO77050.1 - 0.11 12.0 0.2 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 CDO77050.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 CDO77050.1 - 0.14 11.2 0.0 5.1 6.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein P5CR_dimer PF14748.6 CDO77050.1 - 0.17 12.1 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation ABC_tran PF00005.27 CDO77052.1 - 2.6e-50 170.5 0.1 2.2e-24 86.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CDO77052.1 - 4.1e-21 74.8 2.5 4.1e-21 74.8 2.5 2.1 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 CDO77052.1 - 3.3e-16 60.0 3.1 0.0013 18.6 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CDO77052.1 - 2.8e-09 37.8 5.1 0.00046 20.7 0.0 3.7 4 0 0 4 4 3 2 AAA domain SMC_N PF02463.19 CDO77052.1 - 3.6e-09 36.4 4.4 0.17 11.3 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CDO77052.1 - 1e-08 34.8 0.7 0.00091 18.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CDO77052.1 - 3.8e-08 33.9 0.0 0.00056 20.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CDO77052.1 - 1e-06 28.8 0.8 0.0012 18.7 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 CDO77052.1 - 3.2e-06 27.2 0.2 0.004 17.2 0.1 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase NACHT PF05729.12 CDO77052.1 - 4.9e-06 26.6 0.0 0.064 13.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.6 CDO77052.1 - 9.1e-06 25.6 11.3 0.058 13.1 0.2 4.5 3 2 0 4 4 4 2 AAA ATPase domain Dynamin_N PF00350.23 CDO77052.1 - 8.1e-05 22.7 9.4 0.019 15.0 0.2 4.3 2 2 0 3 3 3 2 Dynamin family AAA_22 PF13401.6 CDO77052.1 - 9.6e-05 22.7 0.3 0.18 12.0 0.1 3.1 2 2 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CDO77052.1 - 0.00012 22.4 1.8 2.2 8.7 0.0 3.6 3 0 0 3 3 3 1 RNA helicase AAA_24 PF13479.6 CDO77052.1 - 0.00019 21.3 0.2 0.75 9.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CDO77052.1 - 0.00025 20.8 0.2 0.024 14.3 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_25 PF13481.6 CDO77052.1 - 0.0011 18.6 0.1 3.9 7.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 CDO77052.1 - 0.0056 16.1 0.2 1.9 7.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.6 CDO77052.1 - 0.0058 16.9 0.0 0.81 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CDO77052.1 - 0.0074 15.6 0.3 0.32 10.2 0.1 3.0 3 0 0 3 3 3 1 Zeta toxin KAP_NTPase PF07693.14 CDO77052.1 - 0.0081 15.4 0.1 2.2 7.5 0.0 2.7 2 1 0 2 2 2 1 KAP family P-loop domain AAA_5 PF07728.14 CDO77052.1 - 0.0094 16.0 0.1 5.9 6.9 0.1 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 CDO77052.1 - 0.0095 16.1 0.0 3.7 7.8 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CDO77052.1 - 0.0099 15.1 0.0 1.6 7.8 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain NTPase_1 PF03266.15 CDO77052.1 - 0.01 15.8 0.8 1.5 8.7 0.2 3.1 3 0 0 3 3 3 0 NTPase AAA PF00004.29 CDO77052.1 - 0.01 16.2 0.1 8.3 6.8 0.1 3.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 CDO77052.1 - 0.011 15.3 0.0 0.072 12.6 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF87 PF01935.17 CDO77052.1 - 0.013 15.6 5.0 1.7 8.7 0.2 3.7 3 2 2 5 5 3 0 Helicase HerA, central domain AAA_18 PF13238.6 CDO77052.1 - 0.014 15.9 0.5 8.4 6.9 0.1 3.2 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CDO77052.1 - 0.019 15.1 0.2 12 6.0 0.1 3.0 3 1 0 3 3 2 0 AAA domain AAA_7 PF12775.7 CDO77052.1 - 0.024 14.2 0.1 1.9 8.0 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region Septin PF00735.18 CDO77052.1 - 0.04 13.2 1.5 3.1 7.0 0.0 3.1 4 0 0 4 4 3 0 Septin AAA_27 PF13514.6 CDO77052.1 - 0.041 13.5 0.0 18 4.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF3987 PF13148.6 CDO77052.1 - 0.051 12.6 0.3 5.8 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) ATP-synt_ab PF00006.25 CDO77052.1 - 0.056 13.1 0.0 4.1 7.0 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase3 PF18751.1 CDO77052.1 - 0.09 12.7 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 G-alpha PF00503.20 CDO77052.1 - 0.091 11.9 3.3 2.9 7.0 0.0 2.8 2 2 0 2 2 2 0 G-protein alpha subunit TsaE PF02367.17 CDO77052.1 - 0.096 12.7 0.7 31 4.6 0.0 3.5 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 CDO77052.1 - 0.15 12.3 0.1 11 6.4 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DivIC PF04977.15 CDO77052.1 - 0.32 10.8 4.9 9.8 6.0 0.1 2.6 2 0 0 2 2 2 0 Septum formation initiator AAA_13 PF13166.6 CDO77052.1 - 0.35 9.5 4.8 2.7 6.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain Pox_A32 PF04665.12 CDO77052.1 - 2.1 7.7 6.2 10 5.5 0.1 3.1 3 1 1 4 4 4 0 Poxvirus A32 protein adh_short PF00106.25 CDO77053.1 - 5.1e-40 137.0 0.0 6.5e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO77053.1 - 7.4e-27 94.4 0.0 9.6e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO77053.1 - 1.7e-05 24.8 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CDO77053.1 - 0.012 15.1 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF5623 PF18536.1 CDO77053.1 - 0.097 13.0 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Arrestin_N PF00339.29 CDO77054.1 - 2.9e-09 37.2 0.0 2.5e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 CDO77054.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Rgp1 MG3 PF17791.1 CDO77054.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Macroglobulin domain MG3 CxC4 PF18717.1 CDO77056.1 - 7.8e-44 148.7 2.8 7.8e-44 148.7 2.8 2.0 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases VWA_N2 PF16164.5 CDO77056.1 - 0.1 12.7 1.8 1.3 9.2 0.2 3.0 2 0 0 2 2 2 0 VWA N-terminal Zn-ribbon_8 PF09723.10 CDO77056.1 - 0.52 10.5 8.8 7.1 6.8 1.0 3.6 3 0 0 3 3 3 0 Zinc ribbon domain MULE PF10551.9 CDO77058.1 - 0.0016 18.8 0.2 0.0077 16.6 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain DUF1668 PF07893.13 CDO77058.1 - 0.021 14.2 0.1 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) Zn-ribbon_8 PF09723.10 CDO77058.1 - 0.021 14.9 2.5 1 9.5 0.6 2.6 2 0 0 2 2 2 0 Zinc ribbon domain AMP-binding PF00501.28 CDO77060.1 - 2.3e-12 46.3 0.0 6.3e-12 44.8 0.0 1.7 2 1 0 2 2 2 1 AMP-binding enzyme GH3 PF03321.13 CDO77060.1 - 0.00044 19.2 0.1 0.00079 18.4 0.1 1.3 1 0 0 1 1 1 1 GH3 auxin-responsive promoter PDEase_I PF00233.19 CDO77061.1 - 4.9e-48 163.9 0.0 7.8e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Peptidase_M28 PF04389.17 CDO77065.1 - 2e-27 96.2 0.1 4.2e-27 95.1 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CDO77065.1 - 1.8e-07 31.1 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CDO77065.1 - 0.042 12.9 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase MR_MLE_C PF13378.6 CDO77066.1 - 2.8e-48 164.4 0.2 2.8e-47 161.1 0.2 2.0 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 CDO77066.1 - 4.6e-08 33.3 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain LPD11 PF18824.1 CDO77066.1 - 0.012 15.7 2.0 0.019 15.0 0.2 2.3 3 1 0 3 3 3 0 Large polyvalent protein-associated domain 11 Abhydrolase_6 PF12697.7 CDO77067.1 - 6.7e-13 49.7 2.5 6.7e-13 49.7 2.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO77067.1 - 1.2e-08 34.6 0.1 0.00017 20.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDO77067.1 - 2.5e-05 24.1 0.1 0.00083 19.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CDO77067.1 - 0.087 12.6 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family F-box-like PF12937.7 CDO77068.1 - 2e-11 43.6 1.0 5.9e-11 42.1 1.0 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CDO77068.1 - 0.0026 17.6 0.5 0.0058 16.5 0.5 1.6 1 0 0 1 1 1 1 F-box HET PF06985.11 CDO77069.1 - 2.8e-10 40.7 0.0 3.6e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bud13 PF09736.9 CDO77070.1 - 1.2e-55 187.9 8.7 1.2e-55 187.9 8.7 2.9 2 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Sec23_trunk PF04811.15 CDO77071.1 - 7.9e-49 166.4 0.0 1.3e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CDO77071.1 - 2.1e-18 66.9 0.0 4e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CDO77071.1 - 6.7e-15 54.9 4.1 1.2e-14 54.0 4.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 CDO77071.1 - 2.6e-12 46.5 0.1 5e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 CDO77071.1 - 0.024 14.6 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Gelsolin repeat Fungal_TACC PF12709.7 CDO77072.1 - 0.0062 17.0 8.2 0.011 16.2 3.8 2.3 1 1 0 2 2 2 1 Fungal Transforming acidic coiled-coil (TACC) proteins TMCO5 PF14992.6 CDO77072.1 - 0.007 16.0 10.2 0.0095 15.5 10.2 1.1 1 0 0 1 1 1 1 TMCO5 family DUF4407 PF14362.6 CDO77072.1 - 0.098 12.0 13.8 0.15 11.4 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 CDO77072.1 - 0.13 12.4 13.2 2.9 8.1 0.0 3.4 3 0 0 3 3 3 0 bZIP transcription factor Spc7 PF08317.11 CDO77072.1 - 0.21 10.5 16.9 0.29 10.0 16.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Borrelia_REV PF03978.13 CDO77072.1 - 0.56 10.1 3.3 0.79 9.7 2.6 1.5 1 1 0 1 1 1 0 Borrelia burgdorferi REV protein PIN_9 PF18477.1 CDO77072.1 - 0.95 9.8 5.3 3.4 8.0 5.1 1.9 1 1 0 1 1 1 0 PIN like domain V_ATPase_I PF01496.19 CDO77072.1 - 2.1 6.2 3.0 2.5 5.9 3.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 CDO77072.1 - 2.1 8.9 21.7 4.8 7.7 21.2 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 CDO77072.1 - 2.6 8.2 23.5 4.2 7.5 13.7 2.9 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FapA PF03961.13 CDO77072.1 - 3.4 6.2 5.7 5 5.6 5.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF641 PF04859.12 CDO77072.1 - 5.4 7.4 16.7 5.8 7.3 8.1 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) NAP PF00956.18 CDO77072.1 - 6.6 5.8 8.5 32 3.6 8.8 1.8 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) FAM184 PF15665.5 CDO77072.1 - 7.7 6.2 19.6 38 4.0 19.5 1.8 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DUF3584 PF12128.8 CDO77072.1 - 8.6 3.7 20.2 12 3.3 20.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4201 PF13870.6 CDO77072.1 - 9.3 5.9 17.1 68 3.1 17.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) UPF0242 PF06785.11 CDO77072.1 - 9.9 6.2 12.9 14 5.7 12.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 CDO77072.1 - 9.9 6.2 15.3 29 4.7 0.4 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DSPc PF00782.20 CDO77073.1 - 8.2e-27 93.6 0.0 1.2e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CDO77073.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CDO77073.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.7 1 1 0 1 1 1 0 Rit1 DUSP-like domain UreD PF01774.17 CDO77074.1 - 7.2e-57 192.7 0.1 8.4e-57 192.5 0.1 1.0 1 0 0 1 1 1 1 UreD urease accessory protein Ribosomal_L24e PF01246.20 CDO77074.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L24e RNA_pol_L_2 PF13656.6 CDO77075.1 - 1.3e-16 60.1 0.0 2.4e-15 56.1 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CDO77075.1 - 4.2e-06 26.1 0.0 0.00019 20.8 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NMO PF03060.15 CDO77077.1 - 3.7e-38 131.7 0.6 5.9e-24 85.1 0.1 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 CDO77077.1 - 1.4e-05 24.3 0.1 0.00012 21.2 0.2 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CDO77077.1 - 0.0055 15.8 0.1 0.007 15.4 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1902 PF08972.11 CDO77077.1 - 0.17 11.9 0.1 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Formyl_trans_N PF00551.19 CDO77078.1 - 2e-20 73.3 0.0 2.9e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CDO77078.1 - 1.9e-10 40.9 0.0 3.1e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MutS_V PF00488.21 CDO77079.1 - 2.4e-42 145.1 0.3 1.7e-34 119.5 0.1 2.5 1 1 1 2 2 2 2 MutS domain V MutS_I PF01624.20 CDO77079.1 - 4.8e-34 117.0 0.2 9.7e-34 116.0 0.2 1.6 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 CDO77079.1 - 3.1e-18 66.7 0.5 5e-14 53.0 0.0 2.8 1 1 1 2 2 2 2 MutS domain III MutS_II PF05188.17 CDO77079.1 - 3.1e-12 47.0 0.0 1.1e-11 45.2 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CDO77079.1 - 6e-09 36.1 0.3 1.3e-08 35.1 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV PBP1_TM PF14812.6 CDO77079.1 - 0.21 11.9 8.0 0.3 11.5 4.9 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peroxidase_ext PF11895.8 CDO77080.1 - 1.1e-31 108.5 2.3 2.4e-31 107.5 2.3 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 CDO77080.1 - 8.5e-28 97.6 0.0 1.3e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Pkinase PF00069.25 CDO77081.1 - 8.3e-49 166.3 0.0 1.1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO77081.1 - 1e-22 80.7 0.0 1.4e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO77081.1 - 9.6e-11 41.5 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDO77081.1 - 0.00024 20.5 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_3 PF14593.6 CDO77081.1 - 0.017 15.2 0.0 0.045 13.9 0.0 1.7 2 0 0 2 2 2 0 PH domain APH PF01636.23 CDO77081.1 - 0.032 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CDO77081.1 - 0.099 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Nup96 PF12110.8 CDO77082.1 - 1e-95 320.2 0.0 1.8e-95 319.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nop14 PF04147.12 CDO77082.1 - 2.3 6.3 11.4 3.7 5.7 11.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CDO77082.1 - 2.5 6.3 5.9 3.6 5.8 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3292 PF11696.8 CDO77082.1 - 3.4 5.9 5.9 5.1 5.3 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) zf_C2H2_13 PF18508.1 CDO77083.1 - 0.11 12.1 0.0 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 Zinc finger domain CLTH PF10607.9 CDO77084.1 - 2.2e-32 112.0 0.1 3.6e-32 111.3 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Transp_cyt_pur PF02133.15 CDO77085.1 - 1e-119 400.2 41.5 1.8e-118 396.1 41.5 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SAYSvFN PF10260.9 CDO77085.1 - 0.17 11.8 3.6 0.52 10.3 0.2 3.5 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) MPS-4 PF17523.2 CDO77085.1 - 0.43 10.7 3.7 10 6.3 0.1 2.9 3 0 0 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 DUF2263 PF10021.9 CDO77086.1 - 1.3e-26 93.7 0.1 5.3e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) 6PF2K PF01591.18 CDO77087.1 - 4e-46 157.1 0.0 9.1e-26 90.5 0.0 2.3 1 1 1 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CDO77087.1 - 4.1e-26 91.9 0.0 8.4e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CDO77087.1 - 0.0002 21.5 0.0 0.00035 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CDO77087.1 - 0.046 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RRM_1 PF00076.22 CDO77088.1 - 3e-10 39.8 0.1 7.9e-10 38.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CDO77088.1 - 5.9e-06 26.7 2.2 1.2e-05 25.8 2.2 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 MFS_1 PF07690.16 CDO77089.1 - 4e-12 45.7 32.8 9e-07 28.1 5.8 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CDO77090.1 - 1.2e-20 73.8 25.4 1.2e-20 73.8 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CDO77090.1 - 1.2e-05 24.8 7.4 1.2e-05 24.8 7.4 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 CDO77091.1 - 2.6e-23 82.5 36.4 6e-18 64.9 8.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CDO77091.1 - 1.6e-05 24.4 1.8 1.6e-05 24.4 1.8 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB HLH PF00010.26 CDO77093.1 - 6.3e-09 35.7 0.0 1.7e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NARP1 PF12569.8 CDO77094.1 - 0.48 9.3 5.7 0.62 8.9 5.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NINJA_B PF16136.5 CDO77094.1 - 1.2 9.5 11.6 0.25 11.7 7.7 1.8 2 0 0 2 2 2 0 Putative nuclear localisation signal RR_TM4-6 PF06459.12 CDO77094.1 - 1.4 8.7 5.7 0.26 11.1 2.0 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MAP65_ASE1 PF03999.12 CDO77094.1 - 1.5 7.5 10.5 1.7 7.3 10.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Presenilin PF01080.17 CDO77094.1 - 1.9 7.2 2.7 2.4 6.8 2.7 1.2 1 0 0 1 1 1 0 Presenilin MMR_HSR1 PF01926.23 CDO77095.1 - 2.3e-10 40.6 0.0 5.8e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CDO77095.1 - 0.00048 20.5 1.1 0.0011 19.4 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 CDO77095.1 - 0.0063 16.4 0.0 0.016 15.2 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 CDO77095.1 - 0.0063 17.1 0.5 0.15 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.18 CDO77095.1 - 0.0078 15.8 0.3 0.013 15.0 0.3 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.6 CDO77095.1 - 0.032 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 CDO77095.1 - 0.065 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain IIGP PF05049.13 CDO77095.1 - 0.088 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 CDO77095.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.18 CDO77095.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arf PF00025.21 CDO77095.1 - 0.23 10.9 0.0 0.44 10.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Exo_endo_phos_2 PF14529.6 CDO77096.1 - 2.5e-06 27.3 0.0 5.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC_6 PF15288.6 CDO77096.1 - 0.064 13.1 1.9 0.17 11.8 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle HIP1_clath_bdg PF16515.5 CDO77096.1 - 0.17 12.5 5.2 0.25 12.0 3.4 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-CCHC_5 PF14787.6 CDO77096.1 - 0.23 11.2 2.9 0.5 10.1 2.9 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF3716 PF12511.8 CDO77096.1 - 0.49 10.5 13.0 1.4 9.0 7.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) THOC7 PF05615.13 CDO77096.1 - 1 9.6 5.0 0.41 10.9 1.7 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 CHD5 PF04420.14 CDO77097.1 - 9.8e-58 194.5 2.0 1.2e-57 194.2 2.0 1.1 1 0 0 1 1 1 1 CHD5-like protein Malate_synthase PF01274.22 CDO77098.1 - 1.1e-199 664.1 0.0 1.3e-199 663.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Pkinase PF00069.25 CDO77099.1 - 2.4e-21 76.3 0.0 8.5e-17 61.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO77099.1 - 2.8e-15 56.3 0.0 4.4e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CDO77099.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CDO77099.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Smr PF01713.21 CDO77100.1 - 3.9e-08 33.5 0.0 7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Smr domain HlyIII PF03006.20 CDO77101.1 - 1.3e-38 132.9 19.1 2.4e-38 132.1 19.1 1.4 1 0 0 1 1 1 1 Haemolysin-III related DUF1129 PF06570.11 CDO77101.1 - 0.094 12.2 1.1 0.15 11.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2070 PF09843.9 CDO77101.1 - 0.86 7.8 3.8 1.3 7.2 3.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC2_membrane_5 PF13346.6 CDO77101.1 - 2.6 7.5 8.8 1 8.9 6.1 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein F-box PF00646.33 CDO77102.1 - 9.1e-07 28.6 0.4 2.7e-06 27.1 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO77102.1 - 0.00016 21.5 0.3 0.0004 20.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like TFIID_20kDa PF03847.13 CDO77103.1 - 4.8e-29 100.6 0.5 7.9e-29 100.0 0.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CDO77103.1 - 0.00088 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CDO77103.1 - 0.0066 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CDO77103.1 - 0.072 13.2 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold Afaf PF15339.6 CDO77104.1 - 0.069 12.9 0.3 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Acrosome formation-associated factor Collagen_mid PF15984.5 CDO77104.1 - 0.14 11.9 1.1 0.42 10.3 0.1 2.1 2 0 0 2 2 2 0 Bacterial collagen, middle region RNase_H PF00075.24 CDO77106.1 - 0.11 12.6 0.0 0.37 10.9 0.0 1.8 1 1 0 1 1 1 0 RNase H Mitoc_L55 PF09776.9 CDO77107.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 DUF4588 PF15251.6 CDO77108.1 - 0.0014 18.4 0.7 0.0037 17.1 0.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) CCDC53 PF10152.9 CDO77108.1 - 0.079 13.4 0.7 0.079 13.4 0.7 2.0 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex MAP65_ASE1 PF03999.12 CDO77108.1 - 0.097 11.4 0.7 0.12 11.0 0.7 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PRP38_assoc PF12871.7 CDO77108.1 - 2.5 8.8 11.5 0.79 10.4 1.0 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term F-box PF00646.33 CDO77109.1 - 0.0021 17.9 0.2 0.0043 16.9 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO77109.1 - 0.011 15.7 0.7 0.022 14.6 0.7 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 CDO77110.1 - 3e-07 30.2 0.8 8.9e-07 28.6 0.8 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO77110.1 - 0.00026 20.8 2.0 0.0019 18.0 2.1 2.3 2 0 0 2 2 2 1 F-box-like MARVEL PF01284.23 CDO77111.1 - 7.8e-05 22.7 11.9 7.8e-05 22.7 11.9 1.4 1 1 0 1 1 1 1 Membrane-associating domain UPF0182 PF03699.13 CDO77111.1 - 0.22 9.6 7.8 0.042 12.0 4.8 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) E1-E2_ATPase PF00122.20 CDO77112.1 - 1.4e-38 132.3 1.1 1.4e-38 132.3 1.1 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CDO77112.1 - 3.3e-32 111.7 3.6 3.3e-32 111.7 3.6 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CDO77112.1 - 2.5e-21 77.0 2.2 3.7e-10 40.4 0.2 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CDO77112.1 - 4e-16 58.9 0.0 7.9e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDO77112.1 - 3.3e-08 33.1 0.0 7e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CDO77112.1 - 5.9e-08 32.8 0.4 1e-07 32.0 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CDO77112.1 - 0.00012 22.5 0.4 0.076 13.4 0.1 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.17 CDO77113.1 - 6.9e-46 156.6 0.0 1.1e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CDO77113.1 - 3e-38 131.7 0.0 5e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 CDO77113.1 - 0.00045 19.9 0.1 0.00081 19.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CDO77113.1 - 0.0019 17.6 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family nec1 PF10379.9 CDO77114.1 - 0.14 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Virulence protein nec1 DUF883 PF05957.13 CDO77115.1 - 0.58 10.8 6.1 6.2 7.5 2.6 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Abhydrolase_3 PF07859.13 CDO77116.1 - 2.2e-25 89.8 0.0 2.9e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 CDO77116.1 - 0.032 13.8 0.0 0.067 12.7 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CDO77117.1 - 5.2e-42 144.1 0.0 6.9e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CDO77117.1 - 0.00039 19.4 0.0 0.0012 17.8 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Myb_DNA-bind_5 PF13873.6 CDO77118.1 - 0.0043 17.1 0.1 0.02 15.0 0.3 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 CDO77118.1 - 0.13 12.6 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3693 PF12472.8 CDO77118.1 - 0.15 11.8 0.4 0.29 10.8 0.4 1.5 1 0 0 1 1 1 0 Phage related protein APC_N_CC PF16689.5 CDO77119.1 - 0.012 15.7 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain SSFA2_C PF14723.6 CDO77119.1 - 0.3 11.0 0.0 0.3 11.0 0.0 2.9 2 1 1 3 3 3 0 Sperm-specific antigen 2 C-terminus Metallophos_2 PF12850.7 CDO77120.1 - 5.5e-16 59.2 0.1 7.8e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CDO77120.1 - 8.3e-07 29.7 0.3 0.021 15.4 0.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase UPF0203 PF05254.12 CDO77121.1 - 1.6e-26 92.3 2.7 2.2e-26 91.9 2.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 CDO77121.1 - 0.025 14.8 2.7 1.9 8.8 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 CDO77121.1 - 0.046 14.0 1.6 5 7.5 0.3 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 CDO77121.1 - 0.071 13.5 1.0 3.9 7.9 0.2 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) COX6B PF02297.17 CDO77121.1 - 0.41 10.9 6.5 10 6.4 6.5 2.1 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Zn_clus PF00172.18 CDO77122.1 - 6.3e-08 32.6 11.3 6.3e-08 32.6 11.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Yippee-Mis18 PF03226.14 CDO77123.1 - 1.6e-13 50.7 0.0 2.2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Gin PF10764.9 CDO77123.1 - 0.043 13.8 0.3 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin SelR PF01641.18 CDO77123.1 - 0.12 12.5 0.1 0.29 11.2 0.1 1.6 1 1 0 1 1 1 0 SelR domain Amidohydro_1 PF01979.20 CDO77124.1 - 1.4e-15 57.5 0.0 6.9e-12 45.3 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CDO77124.1 - 0.00032 20.3 0.1 0.00086 18.9 0.1 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.14 CDO77124.1 - 0.015 15.1 0.3 0.055 13.2 0.0 1.8 1 1 1 2 2 2 0 Amidohydrolase Pkinase_fungal PF17667.1 CDO77125.1 - 3.9e-25 88.5 0.0 1.4e-24 86.7 0.0 1.7 1 1 1 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 CDO77125.1 - 0.0028 17.1 0.0 0.094 12.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain DUF2267 PF10025.9 CDO77126.1 - 0.052 13.8 0.3 0.12 12.7 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) ATP-synt_C PF00137.21 CDO77127.1 - 1.8e-25 89.0 26.1 3.9e-15 55.9 7.8 2.3 2 0 0 2 2 2 2 ATP synthase subunit C zf-CCHC_3 PF13917.6 CDO77128.1 - 1.4e-18 66.6 0.5 2.1e-18 66.0 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CDO77128.1 - 0.097 12.8 0.8 0.16 12.1 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle Rtt106 PF08512.12 CDO77129.1 - 3.4e-19 69.1 0.0 6e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 CDO77129.1 - 0.0027 17.7 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain Nop14 PF04147.12 CDO77129.1 - 0.7 8.0 13.0 0.93 7.6 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF5423 PF17461.2 CDO77129.1 - 2.7 6.8 4.9 2 7.2 2.8 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5423) CDC45 PF02724.14 CDO77129.1 - 5.2 5.2 8.4 8.5 4.5 8.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S28 PF05577.12 CDO77131.1 - 1.2e-48 166.0 0.0 2.2e-48 165.1 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 SIR2 PF02146.17 CDO77132.1 - 3.4e-44 150.9 0.0 5e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CDO77132.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain pPIWI_RE_Y PF18156.1 CDO77132.1 - 0.061 13.7 1.3 20 5.6 0.4 3.3 3 1 0 3 3 3 0 pPIWI_RE three-gene island domain Y DNA_RNApol_7kD PF03604.13 CDO77132.1 - 0.95 9.2 3.7 3.3 7.5 3.7 1.9 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit SIR2 PF02146.17 CDO77133.1 - 5.8e-09 36.1 0.0 8.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CDO77133.1 - 0.097 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Abhydrolase_3 PF07859.13 CDO77134.1 - 3.4e-13 49.9 0.0 5.7e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CDO77134.1 - 1.7e-07 30.9 0.0 0.0006 19.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 CDO77134.1 - 0.0017 18.0 0.0 1.8 8.1 0.0 2.8 3 0 0 3 3 3 2 Dienelactone hydrolase family COesterase PF00135.28 CDO77134.1 - 0.025 13.5 0.0 0.23 10.3 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Hydrolase_4 PF12146.8 CDO77134.1 - 0.19 10.9 0.7 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Cullin PF00888.22 CDO77135.1 - 3.4e-21 75.5 0.3 4.8e-21 75.0 0.3 1.1 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 CDO77135.1 - 8.9e-17 61.4 0.1 4e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 DUF2235 PF09994.9 CDO77136.1 - 1.4e-60 205.1 0.8 8e-31 107.5 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Transket_pyr PF02779.24 CDO77137.1 - 2e-66 223.0 0.0 3.2e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CDO77137.1 - 1.6e-60 204.6 0.0 2.6e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CDO77137.1 - 1.5e-52 177.3 0.0 2.6e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CDO77137.1 - 3.9e-17 61.6 0.2 7.2e-17 60.7 0.2 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus CoA_transf_3 PF02515.17 CDO77138.1 - 2e-129 431.9 0.0 2.3e-129 431.7 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Glyco_hydro_cc PF11790.8 CDO77138.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Glyco_hydro_30 PF02055.16 CDO77140.1 - 1.4e-28 99.9 2.4 1.9e-28 99.4 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 CDO77140.1 - 5.7e-17 61.9 0.4 9e-17 61.2 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 CDO77140.1 - 0.0031 17.2 0.1 0.027 14.1 0.1 2.1 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Amidase_2 PF01510.25 CDO77140.1 - 0.11 13.0 0.0 0.31 11.5 0.0 1.8 2 0 0 2 2 2 0 N-acetylmuramoyl-L-alanine amidase HD_5 PF13487.6 CDO77140.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 HD domain Aldo_ket_red PF00248.21 CDO77141.1 - 3.2e-66 223.5 0.2 4e-66 223.2 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CDO77142.1 - 2.4e-59 200.9 0.3 1.8e-58 198.1 0.3 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 CDO77144.1 - 2.2e-07 30.5 0.0 4.6e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO77144.1 - 7.1e-05 22.5 0.0 0.00014 21.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Heme_oxygenase PF01126.20 CDO77145.1 - 1.9e-40 138.9 0.0 2.6e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase zf-CCCH PF00642.24 CDO77146.1 - 1.7e-15 56.4 20.0 9.8e-07 28.5 0.8 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CDO77146.1 - 8.1e-15 54.3 19.2 1.3e-05 25.1 3.1 3.7 3 1 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 CDO77146.1 - 1.3e-12 47.2 20.7 5.6e-06 26.0 2.7 3.4 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 CDO77146.1 - 5.7e-10 39.9 8.2 0.0052 17.5 0.2 3.7 4 0 0 4 4 4 3 Torus domain zf-CCCH_2 PF14608.6 CDO77146.1 - 1.7e-08 34.6 22.4 0.01 16.3 0.6 3.7 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CDO77146.1 - 0.0092 16.2 9.7 0.15 12.3 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger containing family zf-RING_2 PF13639.6 CDO77147.1 - 5.2e-11 42.7 1.6 5.2e-11 42.7 1.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CDO77147.1 - 5.6e-10 38.8 0.5 5.6e-10 38.8 0.5 3.1 4 0 0 4 4 4 1 RING-like zinc finger PA PF02225.22 CDO77147.1 - 1.4e-07 31.4 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 CDO77147.1 - 2.2e-07 30.6 1.7 2.2e-07 30.6 1.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO77147.1 - 6.8e-07 29.2 0.5 1.2e-06 28.4 0.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDO77147.1 - 9.3e-06 25.4 1.1 1.8e-05 24.5 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CDO77147.1 - 0.00079 19.7 3.8 0.00079 19.7 3.8 2.8 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDO77147.1 - 0.0011 18.8 1.0 0.0027 17.5 1.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO77147.1 - 0.002 18.1 3.0 0.11 12.6 0.1 2.8 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CDO77147.1 - 0.014 15.3 2.1 0.032 14.1 1.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CDO77147.1 - 5 6.8 5.5 0.65 9.7 0.9 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Gelsolin PF00626.22 CDO77148.1 - 5.8e-32 109.4 0.0 3.1e-16 59.0 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat Inovirus_Gp2 PF11726.8 CDO77148.1 - 0.12 12.3 0.2 0.27 11.2 0.1 1.5 2 0 0 2 2 2 0 Inovirus Gp2 DUF3427 PF11907.8 CDO77148.1 - 0.14 11.4 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) Aldo_ket_red PF00248.21 CDO77149.1 - 2.6e-41 141.8 0.1 1.7e-33 116.1 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family BTB PF00651.31 CDO77150.1 - 0.00085 19.5 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Asp PF00026.23 CDO77151.1 - 9.9e-46 156.6 13.6 3.3e-45 154.9 13.6 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO77151.1 - 2.5e-08 34.3 5.5 3e-05 24.3 0.2 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO77151.1 - 0.0035 18.0 3.7 0.069 13.8 0.5 3.0 3 0 0 3 3 3 1 Aspartyl protease DUF3924 PF13062.6 CDO77151.1 - 0.17 11.8 0.7 0.53 10.3 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3924) gag-asp_proteas PF13975.6 CDO77151.1 - 0.23 12.1 3.1 0.33 11.6 0.1 2.6 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Glyco_transf_34 PF05637.12 CDO77153.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Plavaka PF18759.1 CDO77154.1 - 1.4e-23 83.7 0.0 8.8e-22 77.7 0.0 2.2 2 0 0 2 2 2 2 Plavaka transposase Methyltransf_33 PF10017.9 CDO77155.1 - 2.6e-77 260.0 0.0 7.7e-77 258.5 0.0 1.7 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 CDO77155.1 - 2.8e-20 73.0 4.7 3.7e-10 39.8 0.0 3.0 3 0 0 3 3 3 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 CDO77155.1 - 0.011 16.3 0.1 0.022 15.3 0.1 1.5 1 0 0 1 1 1 0 DinB superfamily LINES_C PF14695.6 CDO77156.1 - 0.093 12.2 0.2 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Lines C-terminus DUF523 PF04463.12 CDO77156.1 - 0.11 12.5 0.2 1.4 9.0 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF523) TORC_N PF12884.7 CDO77156.1 - 0.73 10.7 2.8 4.1 8.3 2.0 2.6 2 1 0 2 2 2 0 Transducer of regulated CREB activity, N terminus Ribonuc_red_lgC PF02867.15 CDO77157.1 - 1.3e-168 561.8 0.0 5.3e-105 351.9 0.0 2.1 1 1 1 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CDO77157.1 - 7.1e-23 80.4 0.0 1.6e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CDO77157.1 - 1.3e-06 28.9 0.0 4.1e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain NUDE_C PF04880.13 CDO77157.1 - 3.1 8.2 8.0 5.4 7.4 8.0 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region F-box-like PF12937.7 CDO77158.1 - 2.4e-09 36.9 1.6 5.8e-09 35.7 1.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO77158.1 - 0.046 13.6 1.9 0.73 9.8 1.9 2.9 1 1 0 1 1 1 0 F-box domain FA_desaturase PF00487.24 CDO77159.1 - 5.1e-25 88.8 23.5 1.5e-24 87.2 23.5 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Pkinase PF00069.25 CDO77160.1 - 2.2e-14 53.5 0.0 4.1e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO77160.1 - 2.9e-06 26.8 0.0 9.5e-06 25.1 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO77160.1 - 0.0039 16.0 0.0 0.011 14.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CDO77160.1 - 0.0079 16.1 0.3 0.045 13.7 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CDO77160.1 - 0.2 11.0 0.0 0.43 9.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_30 PF02055.16 CDO77161.1 - 2.7e-24 85.8 0.2 4.9e-24 85.0 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 CDO77161.1 - 1.6e-14 53.8 0.0 2.6e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 DNA_circ_N PF07157.12 CDO77161.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA circularisation protein N-terminus Methyltransf_33 PF10017.9 CDO77162.1 - 8.6e-61 205.8 0.0 1.9e-60 204.6 0.0 1.5 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent YTH PF04146.15 CDO77163.1 - 2.4e-49 167.5 1.6 1.3e-48 165.1 1.6 2.2 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 CDO77163.1 - 7.8e-06 25.6 0.0 0.0027 17.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CDO77164.1 - 1.9e-15 56.9 0.0 0.00086 20.1 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO77164.1 - 1.1e-06 28.8 0.0 0.32 11.3 0.0 3.6 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CDO77164.1 - 0.00077 19.1 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain Nup160 PF11715.8 CDO77164.1 - 0.0045 15.7 0.2 0.083 11.5 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Frtz PF11768.8 CDO77164.1 - 0.12 10.7 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2415 PF10313.9 CDO77164.1 - 0.36 10.8 1.5 0.92 9.5 0.1 2.5 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) A_deaminase PF00962.22 CDO77165.1 - 3.8e-123 411.0 0.2 5.5e-123 410.5 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase HIGH_NTase1 PF05636.11 CDO77165.1 - 0.073 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Pkinase_fungal PF17667.1 CDO77166.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Plavaka PF18759.1 CDO77168.1 - 2.2e-49 168.4 0.0 2.7e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Cas_Cas1 PF01867.16 CDO77168.1 - 0.046 12.8 0.1 0.059 12.5 0.1 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas1 Integrase_H2C2 PF17921.1 CDO77169.1 - 3.8e-18 65.4 0.1 9.9e-18 64.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO77169.1 - 3.8e-15 56.1 0.0 7e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO77169.1 - 3.8e-07 29.9 0.1 7.4e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CDO77169.1 - 5.2e-07 29.8 0.1 1e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RP-C_C PF11800.8 CDO77170.1 - 1.8 8.6 16.3 3.9 7.5 3.0 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region RVT_1 PF00078.27 CDO77172.1 - 2.6e-23 82.7 0.0 5.9e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CDO77172.1 - 3.6e-22 78.6 0.0 8.7e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO77172.1 - 6.8e-22 77.4 0.1 2e-10 40.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDO77172.1 - 8.6e-20 70.6 0.2 1.8e-19 69.6 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO77172.1 - 2e-14 53.8 0.1 4.9e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO77172.1 - 2.8e-06 27.1 0.5 5.9e-06 26.1 0.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 CDO77172.1 - 0.00012 22.5 0.0 0.00034 21.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO77172.1 - 0.00057 20.5 0.1 0.0014 19.2 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease eIF3g PF12353.8 CDO77173.1 - 0.031 14.7 0.6 0.063 13.7 0.6 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G YdiH PF15930.5 CDO77173.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function zf-CCHC_3 PF13917.6 CDO77173.1 - 0.14 12.1 1.1 0.34 10.9 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Hydrolase PF00702.26 CDO77175.1 - 0.0061 16.9 0.0 0.0071 16.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase tRNA-synt_2 PF00152.20 CDO77176.1 - 1.2e-74 251.2 0.0 2.3e-74 250.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 CDO77176.1 - 4.7e-21 75.1 0.0 6.8e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 CDO77176.1 - 4.8e-05 23.3 0.1 9.1e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CDO77176.1 - 0.0071 15.9 0.1 0.38 10.2 0.1 2.4 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) CDC27 PF09507.10 CDO77176.1 - 4.2 6.6 15.5 6.3 6.1 15.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zip PF02535.22 CDO77176.1 - 9.9 5.3 5.6 13 4.9 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pro_isomerase PF00160.21 CDO77177.1 - 9.5e-38 129.9 0.1 2.4e-37 128.7 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAP1 PF08601.10 CDO77177.1 - 0.85 9.3 13.1 1.1 9.0 13.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 FAM60A PF15396.6 CDO77177.1 - 3.3 7.7 23.5 0.85 9.6 12.4 2.1 1 1 1 2 2 2 0 Protein Family FAM60A Ras PF00071.22 CDO77178.1 - 1.1e-21 77.2 0.1 2.4e-13 50.0 0.0 2.9 1 1 1 2 2 2 2 Ras family RsgA_GTPase PF03193.16 CDO77178.1 - 0.00012 22.0 0.1 0.0014 18.6 0.0 2.0 1 1 1 2 2 2 1 RsgA GTPase Roc PF08477.13 CDO77178.1 - 0.0007 19.8 0.0 0.0014 18.9 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CDO77178.1 - 0.00074 19.1 0.1 0.46 10.0 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain ImcF-related_N PF14331.6 CDO77178.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 ImcF-related N-terminal domain MMR_HSR1 PF01926.23 CDO77178.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.29 CDO77179.1 - 1.4e-52 178.0 0.0 3e-51 173.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CDO77179.1 - 1.1e-15 57.9 0.0 1.2e-13 51.4 0.0 2.5 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO77179.1 - 4.5e-07 30.0 0.0 2.6e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2443 PF10398.9 CDO77179.1 - 0.091 12.8 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF2313 PF10076.9 CDO77179.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) RGS-like PF09128.11 CDO77179.1 - 0.15 11.7 0.5 0.29 10.8 0.5 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Helicase_C PF00271.31 CDO77180.1 - 2.9e-10 40.5 0.2 4.4e-10 39.9 0.2 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain API5 PF05918.11 CDO77180.1 - 2.6 6.7 3.1 3 6.6 3.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ANAPC10 PF03256.16 CDO77183.1 - 1.4e-44 152.0 0.0 2.9e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PHD PF00628.29 CDO77183.1 - 8.5e-08 32.0 8.4 1.7e-07 31.0 8.4 1.6 1 0 0 1 1 1 1 PHD-finger F5_F8_type_C PF00754.25 CDO77183.1 - 0.0056 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain PHD_Oberon PF07227.11 CDO77183.1 - 0.17 11.8 3.0 0.32 10.9 3.0 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein ThiF PF00899.21 CDO77184.1 - 2.1e-45 155.0 0.0 2.9e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CDO77184.1 - 2.8e-14 53.5 0.0 5.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain zf-Tim10_DDP PF02953.15 CDO77185.1 - 3.2e-22 77.9 1.4 4.8e-22 77.4 1.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger NES_C_h PF18208.1 CDO77185.1 - 0.078 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain DUF4010 PF13194.6 CDO77185.1 - 0.12 12.0 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) DnaJ PF00226.31 CDO77186.1 - 4.8e-23 81.0 0.8 1.3e-22 79.7 0.8 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 CDO77186.1 - 1.9e-09 37.5 0.2 4.1e-09 36.5 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CDO77186.1 - 2e-08 34.3 0.5 4.1e-08 33.3 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CDO77186.1 - 0.003 17.9 0.5 0.0069 16.7 0.5 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CDO77186.1 - 0.12 12.4 0.5 0.27 11.3 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger LTXXQ PF07813.12 CDO77186.1 - 0.38 11.5 0.0 0.38 11.5 0.0 3.6 4 1 0 4 4 4 0 LTXXQ motif family protein RVT_2 PF07727.14 CDO77187.1 - 2.1e-58 197.8 0.0 3.3e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_18 PF00704.28 CDO77188.1 - 1.5e-59 202.3 0.0 1.9e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.24 CDO77188.1 - 6.9e-13 48.6 0.0 1.4e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 PX domain adh_short PF00106.25 CDO77189.1 - 7.3e-36 123.5 0.0 9.5e-32 110.0 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO77189.1 - 2.3e-22 79.7 0.0 2.1e-18 66.7 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CDO77189.1 - 0.0013 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CDO77189.1 - 0.0014 18.6 0.1 0.0022 17.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 CDO77189.1 - 0.03 14.6 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 CDO77189.1 - 0.087 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Queuosine_synth PF02547.15 CDO77189.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein PALP PF00291.25 CDO77190.1 - 1.1e-55 189.1 4.9 1.4e-46 159.3 2.7 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Nucleoporin_FG PF13634.6 CDO77191.1 - 0.00099 19.9 17.2 0.00099 19.9 17.2 4.4 1 1 1 2 2 2 1 Nucleoporin FG repeat region TAF4 PF05236.14 CDO77192.1 - 5.2e-34 118.3 4.8 6.4e-34 118.0 4.8 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Sox_N PF12444.8 CDO77192.1 - 0.1 13.7 0.5 0.1 13.7 0.5 2.1 2 1 0 2 2 2 0 Sox developmental protein N terminal ABC_membrane PF00664.23 CDO77193.1 - 7.5e-53 179.9 25.1 6.6e-28 98.1 7.9 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 CDO77193.1 - 8.4e-47 159.1 0.1 4.7e-28 98.4 0.1 3.2 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CDO77193.1 - 1.2e-11 44.5 3.7 0.0047 16.4 0.3 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CDO77193.1 - 8.8e-09 35.6 4.6 0.0077 16.1 0.2 4.3 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDO77193.1 - 6.3e-07 29.0 0.1 0.055 13.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CDO77193.1 - 1.8e-06 28.5 0.5 0.092 13.1 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 CDO77193.1 - 2.2e-06 28.3 4.0 0.00026 21.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 CDO77193.1 - 1e-05 24.8 0.1 0.0019 17.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 CDO77193.1 - 6.3e-05 23.0 0.3 0.11 12.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 CDO77193.1 - 0.00025 21.2 0.7 0.033 14.3 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 CDO77193.1 - 0.00037 20.8 0.5 0.41 10.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CDO77193.1 - 0.00085 18.7 0.0 0.33 10.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 CDO77193.1 - 0.0014 18.3 0.0 0.62 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CDO77193.1 - 0.0015 18.1 0.1 0.5 9.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CDO77193.1 - 0.002 18.1 0.1 0.56 10.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 CDO77193.1 - 0.0022 17.7 0.8 3 7.5 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_15 PF13175.6 CDO77193.1 - 0.0037 17.0 0.8 0.39 10.4 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain ResIII PF04851.15 CDO77193.1 - 0.0044 17.0 0.0 0.62 10.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 CDO77193.1 - 0.011 15.8 0.4 8.7 6.3 0.1 3.3 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CDO77193.1 - 0.019 14.7 0.0 2.8 7.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CDO77193.1 - 0.02 15.4 0.0 6.7 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CDO77193.1 - 0.021 14.7 0.2 1.4 8.8 0.0 3.1 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea DEAD PF00270.29 CDO77193.1 - 0.04 13.7 0.6 16 5.2 0.0 3.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase Roc PF08477.13 CDO77193.1 - 0.06 13.6 0.2 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CDO77193.1 - 0.063 13.3 0.5 5.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 CDO77193.1 - 0.076 13.2 0.0 0.96 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CDO77193.1 - 0.081 12.7 0.2 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Adeno_IVa2 PF02456.15 CDO77193.1 - 0.099 11.4 0.1 0.62 8.8 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF4476 PF14771.6 CDO77193.1 - 0.13 12.6 0.2 0.34 11.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Pox_A32 PF04665.12 CDO77193.1 - 0.15 11.5 1.1 11 5.4 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_11 PF13086.6 CDO77193.1 - 0.17 11.6 1.5 0.58 9.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain Podoplanin PF05808.11 CDO77193.1 - 0.22 11.6 1.5 0.76 9.9 1.5 1.9 1 0 0 1 1 1 0 Podoplanin AAA PF00004.29 CDO77193.1 - 0.22 11.9 0.5 2.2 8.7 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CDO77193.1 - 1 9.3 5.6 4.8 7.1 0.1 3.7 4 0 0 4 4 4 0 NACHT domain cobW PF02492.19 CDO77193.1 - 1.1 8.8 3.6 1.1 8.8 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Tetraspanin PF00335.20 CDO77193.1 - 7 6.3 6.0 11 5.6 1.8 2.6 2 0 0 2 2 2 0 Tetraspanin family Peptidase_M24 PF00557.24 CDO77194.1 - 1.2e-38 132.9 0.0 1.7e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Nup188 PF10487.9 CDO77195.1 - 8.4e-46 156.4 0.0 3.1e-27 95.0 0.0 3.7 3 1 0 3 3 3 2 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 CDO77195.1 - 1.4e-07 30.7 0.1 3.2e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup192 PF11894.8 CDO77195.1 - 0.0021 15.3 0.2 0.0068 13.6 0.0 1.8 2 0 0 2 2 2 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF1741 PF08427.10 CDO77195.1 - 0.13 11.9 1.1 0.35 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) Ribosomal_L13 PF00572.18 CDO77196.1 - 1.9e-53 180.0 0.1 2.3e-53 179.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 X PF00739.19 CDO77196.1 - 0.027 14.6 0.1 0.55 10.3 0.0 2.1 1 1 0 2 2 2 0 Trans-activation protein X DUF572 PF04502.13 CDO77197.1 - 1.5 8.4 20.2 0.15 11.7 14.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) HEPN_Swt1 PF18731.1 CDO77197.1 - 1.5 9.2 4.6 0.39 11.1 0.1 2.4 3 0 0 3 3 3 0 Swt1-like HEPN SH3_1 PF00018.28 CDO77198.1 - 6.6e-15 54.5 0.2 1.3e-14 53.5 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CDO77198.1 - 6.9e-15 54.6 0.1 1.4e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 CDO77198.1 - 9.4e-13 48.1 0.0 1.6e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 CDO77198.1 - 2.6e-12 47.2 0.2 6.7e-12 45.9 0.2 1.7 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 CDO77198.1 - 6.6e-11 42.5 0.0 1.6e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 CDO77198.1 - 2.3e-09 36.8 0.0 4.9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_3 PF18016.1 CDO77198.1 - 0.00045 20.0 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CH PF00307.31 CDO77198.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain SAM_Ste50p PF09235.10 CDO77198.1 - 0.17 12.1 0.2 0.39 11.0 0.2 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_PNT PF02198.16 CDO77198.1 - 0.2 11.6 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain TPR_2 PF07719.17 CDO77199.1 - 6.9e-18 63.3 4.7 0.00031 20.6 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 CDO77199.1 - 1.9e-15 55.9 0.1 0.0011 18.7 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CDO77199.1 - 1.5e-14 54.3 8.9 2.6e-08 34.4 0.0 5.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO77199.1 - 2.8e-12 46.9 0.0 0.038 14.5 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDO77199.1 - 8.1e-12 44.9 10.0 0.0019 18.9 0.0 7.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO77199.1 - 9.7e-12 44.4 0.0 0.00033 20.3 0.0 4.2 3 1 1 4 4 4 3 TPR repeat TPR_12 PF13424.6 CDO77199.1 - 7.9e-10 38.9 7.5 0.00038 20.7 0.0 6.2 3 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CDO77199.1 - 1.1e-09 37.7 0.1 0.5 10.7 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CDO77199.1 - 1.5e-07 31.3 0.0 0.052 13.9 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO77199.1 - 1.3e-06 28.0 9.7 0.29 11.2 0.0 7.1 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDO77199.1 - 6.7e-06 25.8 11.5 0.0073 16.1 0.1 6.2 6 2 2 8 8 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO77199.1 - 9.5e-05 22.5 0.0 0.0034 17.6 0.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CDO77199.1 - 0.0031 18.1 1.2 26 5.7 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 CDO77199.1 - 0.0081 15.9 0.1 1.2 8.9 0.0 3.6 4 0 0 4 4 4 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 CDO77199.1 - 0.011 15.9 15.6 0.27 11.4 0.1 6.1 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 CDO77199.1 - 7.8 7.4 7.0 95 4.1 0.0 4.8 6 0 0 6 6 2 0 Tetratricopeptide repeat Semialdhyde_dhC PF02774.18 CDO77201.1 - 8.1e-38 130.3 0.0 1.1e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CDO77201.1 - 6.8e-28 97.5 0.0 1e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 CDO77201.1 - 0.054 14.2 0.0 0.2 12.4 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 CDO77201.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RNase_PH PF01138.21 CDO77202.1 - 2.1e-16 60.6 0.0 3.5e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CDO77202.1 - 8.1e-05 22.6 0.1 0.00061 19.8 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Dioxygenase_C PF00775.21 CDO77203.1 - 7.3e-18 64.6 0.1 2.3e-17 63.0 0.1 1.7 1 1 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.6 CDO77203.1 - 0.032 14.5 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Glyco_hydro_61 PF03443.14 CDO77204.1 - 2.3e-57 194.2 0.4 2.8e-57 194.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 CDO77204.1 - 1e-13 50.9 7.6 1e-13 50.9 7.6 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain F-box-like PF12937.7 CDO77205.1 - 0.028 14.3 0.2 0.092 12.6 0.2 2.0 1 1 0 1 1 1 0 F-box-like Elongin_A PF06881.11 CDO77205.1 - 0.14 12.7 0.0 0.38 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A SMC_N PF02463.19 CDO77206.1 - 7.4e-21 74.6 0.0 1.3e-20 73.8 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CDO77206.1 - 1.4e-06 29.0 38.3 1.4e-06 29.0 38.3 5.7 2 2 0 2 2 1 1 AAA domain AAA_29 PF13555.6 CDO77206.1 - 0.0059 16.3 0.0 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain TcpS PF17456.2 CDO77206.1 - 0.026 14.6 6.9 0.072 13.1 0.8 3.4 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S AAA PF00004.29 CDO77206.1 - 0.03 14.8 0.8 0.17 12.3 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CDO77206.1 - 0.031 14.0 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein N_NLPC_P60 PF12912.7 CDO77206.1 - 0.21 12.0 2.9 0.27 11.6 1.0 2.2 1 1 1 2 2 2 0 NLPC_P60 stabilising domain, N term AAA_13 PF13166.6 CDO77206.1 - 0.22 10.1 0.0 0.22 10.1 0.0 5.6 3 2 2 5 5 4 0 AAA domain AAA_21 PF13304.6 CDO77206.1 - 0.35 10.6 0.0 0.35 10.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CDO77206.1 - 1.1 9.8 0.0 1.1 9.8 0.0 5.3 4 2 0 5 5 4 0 ABC transporter DUF2730 PF10805.8 CDO77206.1 - 1.5 8.9 17.9 4 7.6 5.3 4.8 4 1 1 5 5 5 0 Protein of unknown function (DUF2730) Ham1p_like PF01725.16 CDO77207.1 - 3e-47 161.0 0.0 6.2e-26 91.5 0.0 2.0 1 1 1 2 2 2 2 Ham1 family Pkinase PF00069.25 CDO77208.1 - 2.7e-50 171.2 0.0 3.7e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO77208.1 - 3.4e-29 101.9 0.0 4.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO77208.1 - 0.00043 20.3 0.1 0.0079 16.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CDO77208.1 - 0.00051 19.4 0.0 0.00071 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CDO77208.1 - 0.0039 16.6 0.3 0.0064 15.9 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CDO77208.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SAP18 PF06487.12 CDO77209.1 - 2.9e-13 50.2 0.0 2.2e-11 44.1 0.0 2.1 1 1 1 2 2 2 2 Sin3 associated polypeptide p18 (SAP18) 2OG-FeII_Oxy_2 PF13532.6 CDO77210.1 - 4.1e-16 59.8 0.0 5.6e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Terpene_synth_C PF03936.16 CDO77211.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain ALF PF03752.13 CDO77211.1 - 0.031 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Short repeats of unknown function Sugar_tr PF00083.24 CDO77212.1 - 1.9e-82 277.5 20.3 2.2e-82 277.3 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO77212.1 - 3.3e-28 98.6 31.3 1.2e-25 90.2 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CDO77212.1 - 4.4e-10 38.6 3.2 6.7e-10 38.0 3.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 CDO77212.1 - 9.4e-07 27.7 7.2 9.4e-07 27.7 7.2 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein COX7C PF02935.16 CDO77212.1 - 1 9.6 6.0 0.74 10.1 1.6 3.0 4 0 0 4 4 4 0 Cytochrome c oxidase subunit VIIc Asp PF00026.23 CDO77213.1 - 3.4e-69 233.7 1.2 4.2e-69 233.4 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO77213.1 - 7.8e-11 42.5 0.8 1.3e-08 35.2 0.2 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO77213.1 - 1.2e-06 29.1 0.4 0.001 19.6 0.0 3.3 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDO77213.1 - 0.00086 19.8 0.1 0.055 14.0 0.0 3.1 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp PF00026.23 CDO77214.1 - 1.1e-71 241.8 2.2 1.5e-71 241.4 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO77214.1 - 2.4e-06 27.9 0.7 0.00033 21.0 0.7 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO77214.1 - 1.8e-05 25.3 3.2 0.0027 18.3 0.1 3.3 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 CDO77214.1 - 0.0054 17.3 0.1 0.43 11.2 0.0 3.0 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1768 PF08719.11 CDO77215.1 - 1.5e-05 25.3 0.0 2.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_1 PF00076.22 CDO77216.1 - 3.6e-06 26.7 0.0 0.064 13.1 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CDO77216.1 - 1.7e-05 24.8 0.0 0.0002 21.3 0.0 2.3 1 1 0 1 1 1 1 RNA binding motif p450 PF00067.22 CDO77217.1 - 4.3e-52 177.4 0.0 6.1e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CDO77218.1 - 0.00058 18.7 0.0 0.0011 17.9 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 zf-MYND PF01753.18 CDO77219.1 - 3.3e-08 33.5 11.4 7.5e-08 32.3 11.4 1.7 1 0 0 1 1 1 1 MYND finger WSC PF01822.19 CDO77220.1 - 1.6e-28 98.7 16.7 2.2e-15 56.6 7.2 2.1 2 0 0 2 2 2 2 WSC domain AP_endonuc_2 PF01261.24 CDO77221.1 - 2.1e-26 92.7 0.0 4.8e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel F-box PF00646.33 CDO77221.1 - 0.0015 18.3 5.3 0.28 11.1 0.6 2.8 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 CDO77221.1 - 0.72 9.8 4.0 1 9.3 0.1 2.5 2 0 0 2 2 2 0 F-box-like zf-MYND PF01753.18 CDO77222.1 - 1.3e-06 28.3 10.7 2.6e-06 27.4 10.7 1.5 1 0 0 1 1 1 1 MYND finger Polysacc_deac_1 PF01522.21 CDO77225.1 - 7.7e-15 54.9 0.0 1.6e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 CDO77225.1 - 0.0025 17.5 0.5 0.01 15.5 0.2 2.0 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 CDO77225.1 - 0.031 12.6 0.1 0.053 11.9 0.0 1.4 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2194) AA_permease_2 PF13520.6 CDO77226.1 - 1.3e-57 195.5 54.0 1.6e-57 195.2 54.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDO77226.1 - 4.5e-17 61.8 43.6 6.9e-17 61.2 43.6 1.3 1 0 0 1 1 1 1 Amino acid permease TMEM126 PF07114.11 CDO77226.1 - 0.067 12.6 0.3 0.067 12.6 0.3 2.1 3 0 0 3 3 3 0 Transmembrane protein 126 TipAS PF07739.13 CDO77227.1 - 0.00016 22.2 1.4 0.00016 22.2 1.4 2.3 1 1 1 2 2 2 1 TipAS antibiotic-recognition domain DUF3584 PF12128.8 CDO77227.1 - 0.0016 16.0 14.1 0.002 15.7 14.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PGBA_C PF15437.6 CDO77227.1 - 0.019 15.3 10.2 0.053 13.9 10.2 1.9 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Alanine_zipper PF11839.8 CDO77227.1 - 0.036 14.4 20.3 0.11 12.9 20.3 1.9 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DUF2229 PF09989.9 CDO77227.1 - 0.42 10.2 3.3 0.64 9.6 3.3 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) FUSC PF04632.12 CDO77227.1 - 2.4 6.6 5.0 2.7 6.4 5.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Glyoxal_oxid_N PF07250.11 CDO77228.1 - 6.9e-35 120.4 0.0 2.4e-34 118.6 0.0 2.0 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CDO77228.1 - 1.4e-19 70.2 0.1 2.7e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 CDO77228.1 - 0.0073 16.2 0.0 1.2 9.2 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Glyoxal_oxid_N PF07250.11 CDO77229.1 - 4.9e-33 114.3 0.0 1.4e-32 112.8 0.0 1.8 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CDO77229.1 - 8.1e-21 74.1 0.1 1.6e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 CDO77229.1 - 0.0089 16.0 0.0 1.1 9.3 0.0 3.5 3 0 0 3 3 3 1 Kelch motif AA_permease PF00324.21 CDO77231.1 - 1.3e-114 383.4 46.8 1.7e-114 383.1 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CDO77231.1 - 4.5e-43 147.7 50.8 6.3e-43 147.2 50.8 1.2 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 CDO77232.1 - 1.8e-12 46.9 0.0 1.8e-12 46.9 0.0 2.2 2 1 0 2 2 1 1 Fungal specific transcription factor domain DUF702 PF05142.12 CDO77232.1 - 0.00062 20.3 6.5 0.0015 19.0 6.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF702) Presenilin PF01080.17 CDO77232.1 - 0.0095 14.7 1.3 0.018 13.8 1.3 1.4 1 0 0 1 1 1 1 Presenilin RPN2_C PF18004.1 CDO77232.1 - 0.016 15.1 3.5 0.29 11.0 3.0 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain HA2 PF04408.23 CDO77232.1 - 0.016 15.4 2.4 0.051 13.9 1.5 2.2 2 0 0 2 2 2 0 Helicase associated domain (HA2) DUF4834 PF16118.5 CDO77232.1 - 0.025 15.5 3.3 0.025 15.5 3.3 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) Roughex PF06020.11 CDO77232.1 - 0.031 13.4 0.9 0.057 12.5 0.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Baculo_PP31 PF05311.11 CDO77232.1 - 0.04 13.4 3.6 0.065 12.7 3.6 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) EOS1 PF12326.8 CDO77232.1 - 0.06 13.3 1.2 0.088 12.7 0.4 1.6 2 0 0 2 2 1 0 N-glycosylation protein TERB2 PF15101.6 CDO77232.1 - 0.062 13.4 7.2 0.1 12.6 7.2 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ABC_tran_CTD PF16326.5 CDO77232.1 - 0.078 13.2 0.2 0.078 13.2 0.2 2.3 2 0 0 2 2 1 0 ABC transporter C-terminal domain DDHD PF02862.17 CDO77232.1 - 0.24 11.5 7.3 0.049 13.8 2.6 2.0 2 0 0 2 2 2 0 DDHD domain UPF0239 PF06783.11 CDO77232.1 - 0.33 11.2 4.7 0.69 10.1 4.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) UPF0560 PF10577.9 CDO77232.1 - 0.62 8.5 11.5 1 7.8 11.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.13 CDO77232.1 - 0.82 9.6 27.0 0.044 13.8 21.5 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LRRC37AB_C PF14914.6 CDO77232.1 - 1.2 9.0 9.6 0.41 10.5 6.5 1.7 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain EIIBC-GUT_N PF03612.14 CDO77232.1 - 1.3 8.7 6.1 2.4 7.9 6.1 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus EMP24_GP25L PF01105.24 CDO77232.1 - 1.7 8.5 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 1 0 emp24/gp25L/p24 family/GOLD ALMT PF11744.8 CDO77232.1 - 1.8 7.3 3.5 6.9 5.4 3.7 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 CDO77232.1 - 1.9 6.3 7.3 0.71 7.7 4.5 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2722 PF10846.8 CDO77232.1 - 2.2 7.1 25.4 3.5 6.5 25.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MID_MedPIWI PF18296.1 CDO77232.1 - 2.2 8.0 12.1 0.37 10.5 5.5 2.1 2 0 0 2 2 2 0 MID domain of medPIWI eIF-3_zeta PF05091.12 CDO77232.1 - 2.3 7.1 10.9 3.4 6.5 10.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 CDO77232.1 - 2.9 7.8 11.7 5 7.0 11.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CCDC53 PF10152.9 CDO77232.1 - 3.4 8.1 10.1 0.37 11.2 3.0 2.3 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex EPL1 PF10513.9 CDO77232.1 - 4.1 7.8 9.3 4 7.8 7.6 1.8 2 0 0 2 2 1 0 Enhancer of polycomb-like Pex14_N PF04695.13 CDO77232.1 - 5.5 7.6 20.1 0.34 11.6 11.3 2.7 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC14 PF08045.11 CDO77233.1 - 1.7e-22 79.9 0.0 1.4e-17 63.7 0.0 2.4 2 0 0 2 2 2 2 Cell division control protein 14, SIN component FAA_hydrolase PF01557.18 CDO77234.1 - 3.1e-60 203.6 0.0 4.1e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxal_oxid_N PF07250.11 CDO77235.1 - 1.4e-33 116.1 0.0 6.5e-33 113.9 0.0 2.0 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CDO77235.1 - 1.4e-20 73.3 0.1 3.2e-20 72.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Arabinose_bd PF12625.7 CDO77236.1 - 0.037 14.1 0.1 0.083 13.0 0.1 1.6 1 0 0 1 1 1 0 Arabinose-binding domain of AraC transcription regulator, N-term F-box-like PF12937.7 CDO77236.1 - 0.053 13.4 2.0 0.23 11.4 0.2 2.7 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.6 CDO77236.1 - 0.22 11.3 5.1 2.1 8.2 1.4 3.5 4 0 0 4 4 4 0 Leucine rich repeat TFIID-18kDa PF02269.16 CDO77237.1 - 2.2e-32 111.0 0.1 4.3e-32 110.0 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 CDO77237.1 - 0.026 14.8 0.6 0.057 13.7 0.6 1.6 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Asp_protease PF09668.10 CDO77238.1 - 3.9e-61 204.3 0.0 6e-61 203.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDO77238.1 - 6.2e-22 78.0 0.0 1.8e-21 76.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO77238.1 - 4.1e-10 40.2 0.0 1.4e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.31 CDO77238.1 - 4e-09 36.2 0.7 8.9e-09 35.1 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 CDO77238.1 - 6.4e-09 35.4 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA_4 PF14555.6 CDO77238.1 - 0.00033 20.4 0.0 0.00077 19.2 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain RVP PF00077.20 CDO77238.1 - 0.0059 16.9 0.0 0.021 15.2 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 CDO77238.1 - 0.0096 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP_2 PF08284.11 CDO77238.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease XPC-binding PF09280.11 CDO77238.1 - 0.031 14.0 1.2 0.044 13.5 0.4 1.7 2 0 0 2 2 2 0 XPC-binding domain Atg29_N PF18388.1 CDO77239.1 - 2e-17 62.8 0.1 3.2e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain RWD PF05773.22 CDO77240.1 - 5.6e-08 33.1 0.0 1.1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 RWD domain UPF0029 PF01205.19 CDO77240.1 - 0.00036 20.8 0.0 0.0011 19.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 SURF2 PF05477.11 CDO77241.1 - 0.29 10.8 11.0 0.5 10.0 11.0 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Cwf_Cwc_15 PF04889.12 CDO77241.1 - 4.9 6.8 15.9 8.7 6.0 15.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 CDO77241.1 - 5.2 7.2 17.4 8.8 6.5 17.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Aldedh PF00171.22 CDO77242.1 - 3.6e-156 520.3 0.6 4e-156 520.1 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Phage_RpbA PF10789.9 CDO77242.1 - 0.21 11.7 0.0 0.49 10.5 0.0 1.6 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA FAM163 PF15069.6 CDO77244.1 - 0.043 14.3 1.5 0.082 13.4 1.5 1.4 1 0 0 1 1 1 0 FAM163 family Beta-APP PF03494.13 CDO77244.1 - 2.2 8.2 6.1 3.9 7.4 6.1 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Big_7 PF17957.1 CDO77245.1 - 0.029 15.1 0.8 4.5 8.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial Ig domain CE2_N PF17996.1 CDO77246.1 - 0.00069 19.6 0.3 0.002 18.1 0.0 1.9 2 1 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Amnionless PF14828.6 CDO77246.1 - 0.15 10.8 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 CDO77246.1 - 0.25 11.3 0.9 0.57 10.1 0.9 1.5 1 0 0 1 1 1 0 Syndecan domain RIFIN PF02009.16 CDO77246.1 - 0.29 11.0 0.0 0.43 10.4 0.0 1.4 1 1 0 1 1 1 0 Rifin Apt1 PF10351.9 CDO77246.1 - 0.34 9.7 6.1 0.45 9.3 6.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CE2_N PF17996.1 CDO77247.1 - 0.038 14.0 0.0 0.56 10.2 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal Hist_deacetyl PF00850.19 CDO77248.1 - 3.6e-58 197.4 0.0 4.5e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Ribosomal_L1 PF00687.21 CDO77249.1 - 1.9e-48 164.9 1.3 2.2e-48 164.7 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MULE PF10551.9 CDO77250.1 - 0.0068 16.8 0.0 0.03 14.7 0.0 2.1 1 0 0 1 1 1 1 MULE transposase domain DUF1668 PF07893.13 CDO77250.1 - 0.056 12.8 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) Zn-ribbon_8 PF09723.10 CDO77250.1 - 0.19 11.9 2.7 3.4 7.9 0.6 2.7 2 0 0 2 2 2 0 Zinc ribbon domain RVT_2 PF07727.14 CDO77251.1 - 2.4e-54 184.6 0.0 3.5e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO77251.1 - 2.3e-12 47.1 0.0 5.8e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO77251.1 - 9.6e-09 35.0 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 CDO77251.1 - 7.7e-05 22.4 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 CDO77251.1 - 0.00051 19.8 0.1 0.002 17.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 CDO77251.1 - 0.041 14.0 0.6 0.089 12.9 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.26 CDO77252.1 - 5e-13 49.3 0.0 8e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDO77252.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Transposase_21 PF02992.14 CDO77253.1 - 2.5e-07 30.1 0.0 6.4e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 PfkB PF00294.24 CDO77257.1 - 1.5e-73 247.8 0.5 1.6e-73 247.6 0.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Cse1 PF08506.10 CDO77258.1 - 0.00061 18.7 0.0 0.0017 17.3 0.0 1.8 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 CDO77258.1 - 0.0018 16.9 0.1 0.067 11.7 0.0 2.8 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus API5 PF05918.11 CDO77258.1 - 0.015 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ParcG PF10274.9 CDO77258.1 - 0.12 12.5 1.9 4.6 7.3 0.1 3.6 4 1 0 4 4 4 0 Parkin co-regulated protein DUF4996 PF16387.5 CDO77258.1 - 0.13 12.7 0.3 0.77 10.3 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function MMS19_C PF12460.8 CDO77258.1 - 0.16 11.0 4.2 12 4.8 0.2 3.9 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 CDO77258.1 - 0.19 12.3 6.5 5.1 7.7 0.0 5.0 5 0 0 5 5 5 0 HEAT-like repeat Malic_M PF03949.15 CDO77260.1 - 1.2e-78 264.0 0.0 3.6e-78 262.4 0.0 1.7 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDO77260.1 - 1.2e-59 201.2 0.0 1.8e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain F-box-like PF12937.7 CDO77261.1 - 3.7e-06 26.7 0.1 1e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like ABC2_membrane_3 PF12698.7 CDO77263.1 - 3.3e-13 49.5 15.3 3.9e-13 49.2 15.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein RCC1 PF00415.18 CDO77264.1 - 4.5e-12 46.4 1.4 8.2e-05 23.1 0.0 4.6 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CDO77264.1 - 3.7e-05 23.4 4.4 0.0004 20.1 0.3 3.8 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat CorA PF01544.18 CDO77265.1 - 1.1e-13 51.2 8.2 5.5e-11 42.3 0.4 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein p450 PF00067.22 CDO77266.1 - 1.9e-23 82.9 0.0 3.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 DUF1631 PF07793.11 CDO77266.1 - 0.27 9.6 0.1 0.53 8.6 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) RdRP PF05183.12 CDO77267.1 - 3e-111 372.9 0.0 4.2e-111 372.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 CDO77269.1 - 3.6e-25 87.6 0.1 9e-14 51.1 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CDO77269.1 - 1.6e-12 47.1 0.0 5.2e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CDO77269.1 - 4.1e-08 33.0 0.0 2.9e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CDO77269.1 - 0.0029 17.6 0.0 0.33 11.0 0.0 2.7 2 1 0 2 2 2 1 Limkain b1 PHM7_cyt PF14703.6 CDO77269.1 - 0.037 14.3 3.4 13 6.0 0.5 3.5 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Malic_M PF03949.15 CDO77270.1 - 5.3e-64 216.0 0.0 7.5e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CDO77270.1 - 3.2e-44 150.9 0.0 7.5e-44 149.7 0.0 1.6 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain LysM PF01476.20 CDO77271.1 - 1.9e-12 47.1 0.0 2.6e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 LysM domain UDPGT PF00201.18 CDO77272.1 - 7.9e-14 51.3 0.1 1.2e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO77272.1 - 7.2e-05 22.8 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Retrotrans_gag PF03732.17 CDO77272.1 - 0.016 15.5 0.0 0.056 13.7 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein Amidohydro_2 PF04909.14 CDO77272.1 - 0.083 12.7 0.2 0.2 11.4 0.2 1.7 1 1 0 1 1 1 0 Amidohydrolase p450 PF00067.22 CDO77274.1 - 1.6e-71 241.4 0.2 1.6e-70 238.1 0.2 2.4 1 1 0 1 1 1 1 Cytochrome P450 Dor1 PF04124.12 CDO77276.1 - 9.9e-56 188.8 5.6 5.2e-55 186.5 5.6 2.0 1 1 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 CDO77276.1 - 3e-07 30.4 0.2 1.2e-06 28.5 0.2 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Vps54_N PF10475.9 CDO77276.1 - 0.0013 18.1 0.6 0.0021 17.4 0.6 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Baculo_PEP_C PF04513.12 CDO77276.1 - 0.43 10.6 9.3 0.036 14.1 1.5 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sugar_tr PF00083.24 CDO77278.1 - 4.9e-123 411.3 11.0 6e-123 411.0 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO77278.1 - 7.7e-17 61.2 34.5 1.4e-12 47.2 13.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Dus PF01207.17 CDO77279.1 - 1.9e-49 168.5 0.0 2.4e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiC_Rad_SAM PF01964.18 CDO77279.1 - 0.055 12.2 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Radical SAM ThiC family Inositol_P PF00459.25 CDO77280.1 - 1e-65 222.0 0.0 1.2e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 CDO77280.1 - 0.18 11.2 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Proteasome PF00227.26 CDO77281.1 - 5.1e-56 189.2 0.0 6.6e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDO77281.1 - 6.5e-14 51.3 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Rotamase PF00639.21 CDO77282.1 - 2.6e-24 86.0 0.0 3.4e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CDO77282.1 - 1.3e-23 83.7 0.0 1.7e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CDO77282.1 - 2.1e-08 34.1 0.2 2.1e-08 34.1 0.2 1.6 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 CDO77282.1 - 1.9e-05 25.5 0.0 2.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain PEP_mutase PF13714.6 CDO77283.1 - 1.5e-13 50.7 0.0 1.9e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase S-methyl_trans PF02574.16 CDO77283.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase MOSC PF03473.17 CDO77284.1 - 2.5e-12 46.9 0.1 1.5e-11 44.4 0.1 2.1 1 1 0 1 1 1 1 MOSC domain Ribonuc_L-PSP PF01042.21 CDO77285.1 - 7.4e-41 139.0 0.3 1.4e-40 138.0 0.1 1.6 2 0 0 2 2 2 1 Endoribonuclease L-PSP K_channel_TID PF07941.11 CDO77286.1 - 0.016 15.6 0.8 0.016 15.6 0.8 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF4554 PF15091.6 CDO77288.1 - 0.033 13.1 1.1 0.047 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) CENP-F_leu_zip PF10473.9 CDO77288.1 - 0.065 13.3 1.6 0.11 12.5 0.2 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.13 CDO77288.1 - 0.16 12.6 2.6 11 6.7 0.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1688 PF07958.11 CDO77290.1 - 6.2e-177 588.5 0.0 7e-177 588.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) AAA_30 PF13604.6 CDO77291.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain SLH PF00395.20 CDO77291.1 - 0.09 12.8 0.1 14 5.8 0.0 2.8 3 0 0 3 3 3 0 S-layer homology domain Exo84_C PF16528.5 CDO77292.1 - 9.2e-41 139.9 0.2 5.7e-40 137.3 0.2 2.2 1 1 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CDO77292.1 - 7.3e-16 58.0 0.8 2e-15 56.6 0.8 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 CDO77292.1 - 0.0003 20.9 2.0 0.0003 20.9 2.0 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec3-PIP2_bind PF15277.6 CDO77292.1 - 0.048 13.8 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_13 PF16652.5 CDO77292.1 - 0.062 13.1 1.2 0.17 11.7 1.2 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain efThoc1 PF11957.8 CDO77293.1 - 1.8e-96 323.8 2.1 2.8e-91 306.6 0.2 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Tuberin PF03542.16 CDO77293.1 - 0.21 10.6 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Tuberin GDP_Man_Dehyd PF16363.5 CDO77294.1 - 2.7e-44 151.9 0.0 3.3e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDO77294.1 - 9.7e-41 139.8 0.0 1.3e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO77294.1 - 1.9e-11 43.5 0.0 5.4e-11 42.0 0.0 1.7 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CDO77294.1 - 9.7e-11 41.3 0.1 6.2e-10 38.7 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CDO77294.1 - 3.1e-09 36.3 0.0 2.1e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 CDO77294.1 - 7.4e-07 29.2 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 CDO77294.1 - 4.5e-06 26.0 0.0 1.1e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein DapB_N PF01113.20 CDO77294.1 - 0.17 12.0 0.0 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.16 CDO77295.1 - 4.4e-12 45.6 36.5 1e-10 41.1 14.4 3.2 1 1 2 3 3 3 2 Major Facilitator Superfamily G-alpha PF00503.20 CDO77298.1 - 1.5e-105 353.3 0.0 2.2e-105 352.7 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDO77298.1 - 9.3e-14 51.3 0.9 8.4e-10 38.4 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CDO77298.1 - 1.3e-05 25.4 0.0 0.047 13.9 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CDO77298.1 - 0.00067 19.1 0.1 0.0012 18.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 CDO77298.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 CDO77298.1 - 0.019 14.2 0.1 0.033 13.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Gtr1_RagA PF04670.12 CDO77298.1 - 0.035 13.5 0.2 8.1 5.7 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 CDO77298.1 - 0.036 14.5 0.1 0.086 13.2 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 CDO77298.1 - 0.051 13.1 0.0 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 CDO77298.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 CDO77298.1 - 0.16 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CDO77298.1 - 0.19 11.3 0.1 23 4.6 0.0 2.5 2 1 0 2 2 2 0 Ras family stn_TNFRSF12A PF12191.8 CDO77300.1 - 0.26 11.5 0.1 0.26 11.5 0.1 2.2 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Strep_pep PF14404.6 CDO77302.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species SNF2_N PF00176.23 CDO77303.1 - 8.2e-69 232.0 0.1 1.7e-68 230.9 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CDO77303.1 - 3e-40 136.8 0.5 3e-40 136.8 0.5 3.2 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 CDO77303.1 - 2.7e-32 111.8 3.0 2.7e-32 111.8 3.0 3.5 5 0 0 5 5 4 1 HAND Helicase_C PF00271.31 CDO77303.1 - 8.1e-20 71.2 0.0 1.5e-18 67.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO77303.1 - 9.5e-10 38.7 0.0 8.2e-09 35.7 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CDO77303.1 - 3.8e-06 26.3 0.0 9.3e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CDO77303.1 - 5.2e-06 26.4 0.0 1.5e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 CDO77303.1 - 0.002 18.5 6.0 0.002 18.5 6.0 4.3 4 0 0 4 4 4 1 DNA-binding domain AAA_14 PF13173.6 CDO77303.1 - 0.0021 18.1 0.2 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Myb_DNA-bind_7 PF15963.5 CDO77303.1 - 0.084 12.8 3.5 1.6 8.7 0.3 3.1 2 0 0 2 2 2 0 Myb DNA-binding like AAA_22 PF13401.6 CDO77303.1 - 0.24 11.7 1.8 9 6.6 0.0 3.6 3 0 0 3 3 3 0 AAA domain Cohesin_load PF10345.9 CDO77305.1 - 1.6e-07 30.2 2.3 0.036 12.5 1.0 3.5 3 1 0 3 3 3 2 Cohesin loading factor DUF4054 PF13262.6 CDO77305.1 - 0.14 12.2 1.4 0.51 10.4 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) DUF4763 PF15960.5 CDO77305.1 - 0.64 9.3 4.0 0.2 10.9 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF604 PF04646.12 CDO77306.1 - 0.098 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 TetR_C_15 PF17918.1 CDO77307.1 - 0.062 14.1 3.9 0.17 12.7 0.6 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FlgN PF05130.12 CDO77308.1 - 0.29 11.6 1.8 0.62 10.6 0.2 2.1 2 1 0 2 2 2 0 FlgN protein Glyco_hydro_47 PF01532.20 CDO77310.1 - 5.2e-155 516.8 0.0 6e-155 516.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 C5-epim_C PF06662.13 CDO77310.1 - 0.0014 18.2 0.0 3.5 7.1 0.0 3.3 3 0 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 CDO77310.1 - 0.05 12.1 0.1 1.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 CDO77310.1 - 0.062 12.4 0.1 4.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.11 CDO77310.1 - 0.079 12.2 0.0 12 5.1 0.0 2.4 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) IF-2B PF01008.17 CDO77311.1 - 1.1e-56 192.1 0.0 1.4e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family SLT PF01464.20 CDO77312.1 - 5e-12 45.5 0.0 1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain Macoilin PF09726.9 CDO77312.1 - 3.3 6.1 4.1 4 5.9 4.1 1.1 1 0 0 1 1 1 0 Macoilin family PPP5 PF08321.12 CDO77313.1 - 4.3e-29 100.6 0.0 1.1e-28 99.3 0.0 1.7 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 CDO77313.1 - 8.7e-27 95.0 0.0 1.7e-26 94.0 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 CDO77313.1 - 6.3e-14 51.1 11.7 3.6e-08 32.9 0.9 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CDO77313.1 - 4.5e-11 42.3 3.7 0.00014 22.0 0.3 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CDO77313.1 - 2.1e-09 36.9 6.8 0.0044 16.7 0.2 3.5 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.17 CDO77313.1 - 7.1e-09 35.1 12.4 6.9e-05 22.7 0.6 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDO77313.1 - 2.5e-07 31.3 0.3 0.0078 16.8 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CDO77313.1 - 2.7e-06 27.8 2.5 0.0038 17.7 0.8 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDO77313.1 - 3.6e-05 23.8 0.1 0.0081 16.3 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CDO77313.1 - 0.00011 22.1 0.7 0.00011 22.1 0.7 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CDO77313.1 - 0.00016 22.2 2.9 0.19 12.6 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDO77313.1 - 0.00063 20.2 4.5 0.0063 17.1 0.8 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CDO77313.1 - 0.0025 17.7 1.9 0.63 10.2 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDO77313.1 - 0.083 13.2 2.3 0.34 11.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO77313.1 - 0.5 10.6 4.6 0.53 10.6 2.4 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Surp PF01805.20 CDO77314.1 - 2.3e-09 37.1 0.3 6e-09 35.8 0.3 1.7 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 CDO77314.1 - 2.6e-09 36.8 0.0 4.8e-07 29.5 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 CDO77314.1 - 0.011 16.6 0.0 0.026 15.3 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. RRM_7 PF16367.5 CDO77314.1 - 0.17 12.0 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif DUF4449 PF14613.6 CDO77314.1 - 2.4 8.2 7.5 6.8 6.8 7.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) KH_1 PF00013.29 CDO77315.1 - 6.2e-91 298.2 28.7 8.6e-15 54.3 0.2 14.0 12 3 0 12 12 12 10 KH domain SLS PF14611.6 CDO77315.1 - 1.7e-12 47.6 11.5 0.00097 19.0 0.1 6.6 7 1 0 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 CDO77315.1 - 7.2e-11 41.8 17.3 0.014 15.2 0.1 8.1 7 2 1 8 8 8 4 KH domain KH_5 PF13184.6 CDO77315.1 - 0.00095 19.2 11.4 0.36 10.9 0.3 5.5 6 0 0 6 6 6 2 NusA-like KH domain KH_4 PF13083.6 CDO77315.1 - 0.0055 16.6 8.1 1 9.3 0.1 5.9 6 0 0 6 6 6 1 KH domain MOEP19 PF16005.5 CDO77315.1 - 0.011 15.8 0.0 0.8 9.7 0.0 3.9 6 0 0 6 6 6 0 KH-like RNA-binding domain Alkyl_sulf_C PF14864.6 CDO77315.1 - 0.019 15.3 0.0 17 5.7 0.0 3.2 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal DUF4974 PF16344.5 CDO77315.1 - 0.024 14.6 0.0 7.6 6.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4974) Repressor_Mnt PF11423.8 CDO77315.1 - 0.067 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Regulatory protein Mnt Secretin_N PF03958.17 CDO77315.1 - 1.1 9.7 4.4 7.3 7.1 0.1 3.7 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain ERO1 PF04137.15 CDO77316.1 - 5.5e-100 335.0 0.0 1.6e-94 317.0 0.0 2.1 1 1 1 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ShK PF01549.24 CDO77316.1 - 0.054 14.0 0.4 0.23 12.0 0.4 2.1 1 0 0 1 1 1 0 ShK domain-like ATP-sulfurylase PF01747.17 CDO77318.1 - 3.8e-87 291.2 0.3 5.3e-87 290.8 0.3 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 CDO77318.1 - 3.5e-51 173.0 0.0 6.4e-51 172.2 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 CDO77318.1 - 9.8e-39 132.8 0.0 1.4e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 CDO77318.1 - 0.00031 21.3 0.0 0.00068 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CDO77318.1 - 0.00098 19.3 0.6 0.0016 18.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CDO77318.1 - 0.024 14.3 0.8 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CDO77318.1 - 0.024 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 CDO77318.1 - 0.052 12.5 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sigma54_activ_2 PF14532.6 CDO77318.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain KTI12 PF08433.10 CDO77318.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 CDO77318.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Asp PF00026.23 CDO77319.1 - 6.1e-23 81.7 0.0 2.8e-21 76.3 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO77319.1 - 0.03 14.6 0.2 5 7.3 0.0 2.4 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO77319.1 - 0.033 14.8 0.2 3.7 8.2 0.1 2.9 2 0 0 2 2 2 0 Aspartyl protease Orf78 PF06024.12 CDO77319.1 - 0.22 11.8 0.0 0.41 11.0 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) LapA_dom PF06305.11 CDO77319.1 - 0.76 9.6 3.5 0.31 10.9 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Asp PF00026.23 CDO77320.1 - 1.8e-13 50.6 0.7 4.7e-10 39.4 0.7 2.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CDO77320.1 - 0.00064 20.3 1.9 0.0099 16.5 0.6 2.8 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CDO77320.1 - 0.00089 19.8 0.7 0.68 10.5 0.1 3.2 2 1 1 3 3 3 1 gag-polyprotein putative aspartyl protease SNF2_N PF00176.23 CDO77321.1 - 1.9e-50 171.6 1.5 2.8e-50 171.0 1.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 CDO77321.1 - 9.5e-24 83.7 0.9 3e-23 82.1 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 CDO77321.1 - 4.2e-19 68.2 4.9 2.7e-15 56.0 0.4 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CDO77321.1 - 3.7e-14 53.0 0.0 1.1e-13 51.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 CDO77321.1 - 6.8e-08 32.9 0.9 6.8e-08 32.9 0.9 4.4 3 1 1 4 4 4 1 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 CDO77321.1 - 2.6e-06 28.0 1.5 8e-06 26.4 0.2 2.6 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 ResIII PF04851.15 CDO77321.1 - 0.00039 20.5 0.0 0.0014 18.6 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CDO77321.1 - 0.0097 15.6 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Myb_DNA-binding PF00249.31 CDO77321.1 - 0.028 14.6 0.0 0.075 13.2 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain CCDC168_N PF15804.5 CDO77321.1 - 5.5 6.8 18.6 0.046 13.6 1.8 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 168 CPP1-like PF11833.8 CDO77322.1 - 0.015 15.0 0.2 0.019 14.6 0.2 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like QueT PF06177.11 CDO77322.1 - 0.076 13.4 1.9 3 8.2 0.2 2.2 1 1 1 2 2 2 0 QueT transporter CRPA PF05745.11 CDO77322.1 - 0.3 11.1 1.8 0.21 11.6 0.3 1.5 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Slu7 PF11708.8 CDO77323.1 - 2.6e-111 371.7 14.0 2.6e-111 371.7 14.0 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor CAP_N PF01213.19 CDO77323.1 - 0.023 14.2 1.3 0.046 13.2 1.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-CCHC_4 PF14392.6 CDO77323.1 - 0.15 11.8 0.3 0.29 10.9 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 CDO77324.1 - 1.5e-62 211.4 0.0 1.8e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO77324.1 - 8.8e-35 120.2 0.0 1.2e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO77324.1 - 0.00029 20.2 0.0 0.0008 18.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CDO77324.1 - 0.0009 18.1 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Joubert PF15392.6 CDO77325.1 - 0.071 12.8 5.7 0.17 11.6 5.7 1.5 1 0 0 1 1 1 0 Joubert syndrome-associated RNase_H2-Ydr279 PF09468.10 CDO77326.1 - 4.6e-19 69.2 0.1 7.9e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 CDO77326.1 - 7.1e-15 55.0 0.0 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain MmgE_PrpD PF03972.14 CDO77327.1 - 7.1e-156 519.1 0.0 9e-156 518.8 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Zn_clus PF00172.18 CDO77328.1 - 1.2e-07 31.8 7.8 1.9e-07 31.1 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.9 CDO77328.1 - 0.023 13.3 3.2 0.03 12.9 3.2 1.1 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 CDO77328.1 - 1.9 7.8 22.3 4 6.8 22.3 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cyclin PF08613.11 CDO77329.1 - 0.0025 18.2 0.0 0.0067 16.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CDO77329.1 - 0.0043 16.8 0.0 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Asp PF00026.23 CDO77331.1 - 8.2e-43 147.0 1.9 1.7e-42 146.0 1.9 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO77331.1 - 4.6e-09 36.8 1.4 2.2e-06 28.0 0.2 2.3 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO77331.1 - 0.039 14.6 1.5 7.2 7.3 0.0 3.4 2 1 0 2 2 2 0 Aspartyl protease DUF3443 PF11925.8 CDO77331.1 - 0.05 12.4 1.0 1.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3443) Acetyltransf_1 PF00583.25 CDO77333.1 - 4.7e-14 52.6 0.0 6.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CDO77333.1 - 9e-10 38.8 0.0 1.3e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CDO77333.1 - 6.1e-09 35.9 0.0 8.1e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CDO77333.1 - 5.9e-06 26.5 0.0 7.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CDO77333.1 - 0.00046 20.1 0.0 0.00084 19.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 CDO77333.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 CDO77333.1 - 0.04 13.7 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ zf-C2H2 PF00096.26 CDO77334.1 - 3.5e-10 39.8 7.2 8.9e-05 22.7 0.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CDO77334.1 - 1.1e-07 31.9 6.5 2.2e-06 27.8 1.0 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CDO77334.1 - 7.4e-07 29.5 5.1 0.032 15.1 1.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CDO77334.1 - 0.019 15.2 9.2 0.15 12.4 0.2 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CDO77334.1 - 0.021 15.5 0.5 0.058 14.1 0.1 2.0 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 CDO77334.1 - 0.034 14.1 2.2 1 9.4 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CDO77334.1 - 0.28 11.0 3.9 9 6.2 0.1 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 CDO77334.1 - 0.61 10.6 10.9 12 6.4 0.4 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type BolA PF01722.18 CDO77334.1 - 0.69 10.2 3.3 27 5.1 0.0 2.9 3 0 0 3 3 3 0 BolA-like protein DNA_ligase_A_M PF01068.21 CDO77335.1 - 1.1e-39 136.3 0.0 5.3e-37 127.5 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CDO77335.1 - 1.9e-32 113.0 0.0 3.5e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CDO77335.1 - 1.4e-17 64.1 0.0 4.4e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Clr2_transil PF16761.5 CDO77337.1 - 3.6e-20 72.6 2.2 8.3e-20 71.4 2.2 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 QSregVF_b PF12843.7 CDO77337.1 - 0.15 11.9 0.1 0.65 9.9 0.1 1.9 2 0 0 2 2 2 0 Putative quorum-sensing-regulated virulence factor gag-asp_proteas PF13975.6 CDO77338.1 - 0.0013 19.2 0.0 0.003 18.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDO77338.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 CDO77338.1 - 0.027 15.1 0.0 0.053 14.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease CAML PF14963.6 CDO77340.1 - 0.055 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand p450 PF00067.22 CDO77341.1 - 2.1e-06 26.8 0.0 2.4e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro-kuma_activ PF09286.11 CDO77343.1 - 1.6e-37 128.9 0.0 3e-35 121.6 0.0 2.2 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CDO77343.1 - 3.1e-07 30.0 0.2 4.7e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Subtilase family UQ_con PF00179.26 CDO77345.1 - 6.1e-42 142.6 0.0 7.9e-42 142.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CDO77345.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain RTA1 PF04479.13 CDO77347.1 - 1.9e-55 187.7 3.2 2.3e-55 187.4 3.2 1.1 1 0 0 1 1 1 1 RTA1 like protein Pkinase PF00069.25 CDO77348.1 - 0.00083 18.8 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 CDO77348.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CDO77348.1 - 0.011 15.7 0.8 0.44 10.4 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 CDO77348.1 - 0.032 13.6 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_SOX PF18371.1 CDO77348.1 - 0.063 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase WaaY PF06176.11 CDO77348.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) MARVEL PF01284.23 CDO77349.1 - 0.0038 17.3 8.6 0.0056 16.7 8.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2339 PF10101.9 CDO77349.1 - 0.15 10.6 6.8 1.3 7.5 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) CAAD PF14159.6 CDO77349.1 - 7.8 6.4 12.8 4.5 7.2 1.8 2.9 2 1 1 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase RTA1 PF04479.13 CDO77350.1 - 7.7e-62 208.6 6.5 7.7e-62 208.6 6.5 1.3 2 0 0 2 2 2 1 RTA1 like protein DUF5056 PF16479.5 CDO77350.1 - 0.0096 16.1 0.3 8.1 6.8 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF5056) Abhydrolase_9_N PF15420.6 CDO77350.1 - 0.013 15.5 1.5 5.9 6.8 0.1 2.8 1 1 2 3 3 3 0 Alpha/beta-hydrolase family N-terminus IncE PF17627.2 CDO77350.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Inclusion membrane protein E Nrap_D4 PF17405.2 CDO77351.1 - 8.5e-65 218.1 0.0 1.6e-64 217.2 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 CDO77351.1 - 1.7e-48 164.7 0.0 3.5e-48 163.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 CDO77351.1 - 1.7e-41 141.5 0.0 1.5e-40 138.5 0.0 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 CDO77351.1 - 1.7e-37 128.8 0.0 2.9e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D5 PF17406.2 CDO77351.1 - 3.6e-33 114.6 0.1 2.2e-25 89.3 0.0 3.5 2 1 1 3 3 3 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D6 PF17407.2 CDO77351.1 - 2.3e-32 112.0 0.0 5.5e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 Glyco_hydro_5_C PF18564.1 CDO77352.1 - 9.7e-26 90.1 0.1 2e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 CDO77352.1 - 1e-12 48.1 0.0 7.2e-09 35.5 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DIOX_N PF14226.6 CDO77353.1 - 6.8e-15 55.9 0.0 1.4e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO77353.1 - 1.1e-13 51.6 0.0 2.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CDO77354.1 - 4.8e-17 62.8 0.0 1.1e-16 61.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO77354.1 - 2e-15 57.1 0.0 4.8e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CDO77355.1 - 1.2e-16 61.5 0.0 3e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO77355.1 - 1.3e-12 48.1 0.0 2.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aldedh PF00171.22 CDO77357.1 - 4.3e-55 187.1 0.0 6.2e-27 94.2 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 CDO77357.1 - 0.0044 16.1 0.0 0.74 8.8 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) Aldedh PF00171.22 CDO77358.1 - 4.5e-59 200.2 0.0 3.1e-30 105.1 0.0 2.2 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 CDO77358.1 - 0.0011 18.1 0.0 0.094 11.7 0.0 2.4 2 1 1 3 3 3 2 Acyl-CoA reductase (LuxC) ATPase-cat_bd PF12156.8 CDO77359.1 - 0.12 13.2 0.1 0.22 12.3 0.1 1.4 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Peptidase_S10 PF00450.22 CDO77360.1 - 2.5e-62 211.7 2.4 8.2e-36 124.3 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase LRRNT_2 PF08263.12 CDO77360.1 - 0.025 14.9 0.1 0.025 14.9 0.1 2.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Peptidase_S10 PF00450.22 CDO77361.1 - 7.5e-75 252.9 0.0 8.9e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2204 PF09970.9 CDO77362.1 - 2.9e-05 23.8 0.0 0.012 15.3 0.0 2.3 2 0 0 2 2 2 2 Nucleotidyl transferase of unknown function (DUF2204) TetR_C_13 PF16925.5 CDO77362.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TauD PF02668.16 CDO77363.1 - 1.2e-47 162.9 0.3 1.7e-47 162.5 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CDO77363.1 - 1.8e-09 38.1 0.1 3.9e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 CDO77363.1 - 0.01 15.0 0.0 0.019 14.1 0.0 1.3 1 1 0 1 1 1 0 CsiD Asp PF00026.23 CDO77364.1 - 5.1e-17 62.3 0.8 8.6e-16 58.2 0.2 2.1 1 1 0 2 2 2 2 Eukaryotic aspartyl protease Asp PF00026.23 CDO77365.1 - 8.2e-34 117.4 2.0 5.9e-33 114.6 2.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CDO77365.1 - 1.1e-05 26.0 0.4 1.1e-05 26.0 0.4 2.2 2 0 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.6 CDO77365.1 - 0.003 17.8 0.4 0.23 11.7 0.0 2.6 1 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 CDO77365.1 - 0.025 15.1 0.7 0.049 14.2 0.0 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Plectin PF00681.20 CDO77365.1 - 0.13 12.1 0.0 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 Plectin repeat MCU PF04678.13 CDO77366.1 - 2.5e-34 118.9 0.7 2.9e-34 118.7 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial calcium uniporter NT-C2 PF10358.9 CDO77367.1 - 1.2e-20 73.7 0.0 1.5e-19 70.1 0.0 2.1 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins PRIMA1 PF16101.5 CDO77368.1 - 0.3 11.1 3.8 0.86 9.7 3.8 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Asp PF00026.23 CDO77369.1 - 3.4e-42 145.0 9.7 1.1e-41 143.3 9.7 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO77369.1 - 3.1e-07 30.8 9.5 5.3e-06 26.8 0.3 3.3 4 1 1 5 5 5 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 CDO77369.1 - 0.058 14.0 1.5 0.42 11.2 0.0 2.7 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease UDPGT PF00201.18 CDO77370.1 - 1.1e-17 64.1 0.1 1.6e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO77370.1 - 0.00011 22.2 0.1 0.00019 21.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 CDO77372.1 - 1.9e-17 63.3 0.1 2.6e-17 62.8 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CDO77372.1 - 0.002 18.1 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Amidohydro_2 PF04909.14 CDO77372.1 - 0.0088 15.9 0.7 0.015 15.1 0.7 1.4 1 1 0 1 1 1 1 Amidohydrolase SOG2 PF10428.9 CDO77375.1 - 0.0045 16.3 0.1 0.0045 16.3 0.1 2.0 1 1 1 2 2 2 1 RAM signalling pathway protein ZapB PF06005.12 CDO77375.1 - 0.0056 17.1 7.6 0.012 16.1 7.6 1.5 1 0 0 1 1 1 1 Cell division protein ZapB PspA_IM30 PF04012.12 CDO77375.1 - 0.008 15.8 0.8 0.016 14.8 0.8 1.4 1 0 0 1 1 1 1 PspA/IM30 family DivIC PF04977.15 CDO77375.1 - 0.0087 15.8 4.3 0.027 14.2 4.4 1.7 1 1 0 1 1 1 1 Septum formation initiator Mod_r PF07200.13 CDO77375.1 - 0.0091 16.1 2.3 0.015 15.4 2.3 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Csm1_N PF18504.1 CDO77375.1 - 0.0094 16.3 3.2 0.017 15.5 3.2 1.4 1 0 0 1 1 1 1 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 CDO77375.1 - 0.01 15.8 1.1 0.019 15.0 1.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BRICHOS PF04089.14 CDO77375.1 - 0.011 16.0 0.1 0.027 14.7 0.1 1.7 1 0 0 1 1 1 0 BRICHOS domain KLRAQ PF10205.9 CDO77375.1 - 0.012 15.8 2.7 0.023 14.9 2.7 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Herpes_UL6 PF01763.16 CDO77375.1 - 0.016 13.8 0.6 0.021 13.3 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Wtap PF17098.5 CDO77375.1 - 0.018 15.0 2.5 0.031 14.2 2.5 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family CdvA PF18822.1 CDO77375.1 - 0.04 13.7 2.7 0.077 12.8 2.7 1.4 1 0 0 1 1 1 0 CdvA-like coiled-coil domain bZIP_1 PF00170.21 CDO77375.1 - 0.041 14.0 2.3 0.077 13.1 2.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor DUF3287 PF11690.8 CDO77375.1 - 0.048 13.4 2.0 1.3 8.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Sipho_Gp157 PF05565.11 CDO77375.1 - 0.054 13.5 0.4 0.085 12.9 0.4 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Cep57_CLD_2 PF14197.6 CDO77375.1 - 0.062 13.4 3.3 0.11 12.6 3.3 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Dzip-like_N PF13815.6 CDO77375.1 - 0.062 13.3 1.8 0.11 12.5 1.8 1.3 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Phlebovirus_NSM PF07246.11 CDO77375.1 - 0.079 12.3 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Cnn_1N PF07989.11 CDO77375.1 - 0.088 13.0 2.4 0.17 12.0 2.4 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 YabA PF06156.13 CDO77375.1 - 0.11 13.2 1.9 0.23 12.1 1.9 1.5 1 0 0 1 1 1 0 Initiation control protein YabA HAP1_N PF04849.13 CDO77375.1 - 0.15 11.2 4.6 0.43 9.7 4.6 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Rho_Binding PF08912.11 CDO77375.1 - 0.17 12.8 2.2 4.2 8.2 2.1 2.3 2 0 0 2 2 2 0 Rho Binding DUF2203 PF09969.9 CDO77375.1 - 0.19 12.5 0.8 0.46 11.2 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) CENP-H PF05837.12 CDO77375.1 - 0.21 12.0 3.6 0.4 11.1 3.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) IFP_35_N PF07334.13 CDO77375.1 - 0.29 11.2 1.7 0.62 10.2 1.7 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spc24 PF08286.11 CDO77375.1 - 0.82 9.9 2.9 1.6 9.0 2.9 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TolA_bind_tri PF16331.5 CDO77375.1 - 1.1 9.4 9.0 0.61 10.2 6.1 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation Lebercilin PF15619.6 CDO77375.1 - 3.8 7.1 10.9 0.24 11.0 5.5 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease XhlA PF10779.9 CDO77375.1 - 4.8 7.4 4.8 3.1 8.1 1.2 2.1 2 0 0 2 2 2 0 Haemolysin XhlA bZIP_2 PF07716.15 CDO77375.1 - 5.8 7.1 9.3 1.5 9.0 3.4 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DAO PF01266.24 CDO77376.1 - 1e-05 25.3 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CDO77376.1 - 0.00014 21.3 0.1 0.00015 21.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CDO77376.1 - 0.00051 20.2 0.3 0.00094 19.4 0.3 1.6 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CDO77376.1 - 0.002 17.4 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDO77376.1 - 0.016 14.3 0.1 0.02 14.0 0.1 1.3 1 1 0 1 1 1 0 FAD binding domain ApbA PF02558.16 CDO77376.1 - 0.03 14.0 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 CDO77376.1 - 0.1 13.1 0.1 0.16 12.6 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDO77377.1 - 1.5e-10 40.8 0.3 2.1e-10 40.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 CDO77377.1 - 0.012 14.6 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase Ribosomal_L24e PF01246.20 CDO77377.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L24e HemY_N PF07219.13 CDO77377.1 - 1.6 9.0 4.1 0.65 10.2 1.7 1.6 2 0 0 2 2 2 0 HemY protein N-terminus rve PF00665.26 CDO77378.1 - 1.6e-17 63.8 0.0 3.5e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO77378.1 - 2.7e-12 46.5 0.0 5.4e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO77378.1 - 2.9e-09 36.6 0.1 7.9e-09 35.3 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO77378.1 - 0.0014 18.4 0.0 0.004 16.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF4219 PF13961.6 CDO77378.1 - 1.4 8.6 5.7 8.8 6.1 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4219) DDE_Tnp_4 PF13359.6 CDO77379.1 - 1.4e-17 63.8 0.0 1.8e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO77379.1 - 4.3e-05 23.3 0.0 9.7e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO77379.1 - 0.0041 16.7 0.1 0.0068 16.0 0.1 1.5 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO77379.1 - 0.05 14.0 0.0 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 Transposase DDE domain Importin_rep PF18773.1 CDO77380.1 - 0.038 13.7 0.4 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Importin 13 repeat Pap_E4 PF02711.14 CDO77380.1 - 5 8.2 6.5 9.2 7.3 2.2 2.7 2 1 0 2 2 2 0 E4 protein Helicase_C PF00271.31 CDO77381.1 - 1.1e-21 77.3 0.1 2e-21 76.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDO77381.1 - 5.2e-17 62.2 0.0 2.2e-16 60.1 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CDO77381.1 - 0.12 12.6 0.5 2.2 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain TLP-20 PF06088.11 CDO77381.1 - 0.94 9.3 6.2 1.8 8.4 6.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) XLF PF09302.11 CDO77382.1 - 0.0017 18.6 0.7 1.1 9.4 0.1 2.4 1 1 1 2 2 2 2 XLF-Cernunnos, XRcc4-like factor, NHEJ component RAP1 PF07218.11 CDO77382.1 - 4.8 5.3 8.3 6.4 4.9 8.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YihI PF04220.12 CDO77382.1 - 6.9 6.4 11.5 14 5.4 11.5 1.5 1 0 0 1 1 1 0 Der GTPase activator (YihI) FHA PF00498.26 CDO77383.1 - 2.1e-08 34.4 0.0 4.3e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 FHA domain G-patch PF01585.23 CDO77383.1 - 1.4e-06 28.1 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDO77383.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 G-patch domain Cyclin_N PF00134.23 CDO77384.1 - 6.8e-44 148.7 0.6 1.6e-43 147.4 0.3 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CDO77384.1 - 1.9e-25 89.3 0.0 4e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Acyl-CoA_dh_1 PF00441.24 CDO77385.1 - 7.6e-24 84.6 2.1 1.1e-23 84.1 2.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CDO77385.1 - 2.9e-17 62.7 0.5 5.1e-17 61.9 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 CDO77385.1 - 8.4e-13 48.3 0.0 2.7e-12 46.6 0.0 2.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 CDO77385.1 - 3.2e-11 43.9 0.2 1.2e-10 42.1 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain UPF0061 PF02696.14 CDO77386.1 - 5.3e-60 203.5 0.0 2.3e-59 201.4 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Actin PF00022.19 CDO77387.1 - 2e-85 286.9 0.0 7.5e-84 281.7 0.0 2.0 1 1 0 1 1 1 1 Actin APG17 PF04108.12 CDO77390.1 - 2.9e-70 237.4 12.0 1.4e-65 222.0 10.8 2.3 2 0 0 2 2 2 2 Autophagy protein Apg17 Goodbye PF17109.5 CDO77390.1 - 0.16 12.4 2.5 56 4.2 0.1 3.5 3 1 0 3 3 3 0 fungal STAND N-terminal Goodbye domain NPV_P10 PF05531.12 CDO77390.1 - 0.39 11.2 8.0 6.3 7.3 0.8 4.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein LXG PF04740.12 CDO77390.1 - 3 7.5 11.2 4.1 7.1 0.6 3.4 2 1 1 3 3 3 0 LXG domain of WXG superfamily DUF1664 PF07889.12 CDO77390.1 - 3.3 7.8 7.0 7.5 6.6 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) FlxA PF14282.6 CDO77390.1 - 4.6 7.3 7.1 2.4 8.2 0.1 2.9 2 1 0 2 2 2 0 FlxA-like protein DUF3416 PF11896.8 CDO77390.1 - 9.9 6.4 8.1 0.46 10.8 1.0 2.3 2 1 0 3 3 3 0 Domain of unknown function (DUF3416) Exo_endo_phos PF03372.23 CDO77391.1 - 6.2e-10 39.0 0.1 1.5e-09 37.7 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myb_DNA-binding PF00249.31 CDO77393.1 - 0.022 14.9 1.8 0.043 14.0 1.8 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain PAT1 PF09770.9 CDO77393.1 - 3.2 5.9 51.8 0.0025 16.2 32.1 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TAP_C PF03943.13 CDO77394.1 - 8.1e-15 54.2 0.1 2.3e-14 52.8 0.1 1.9 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 CDO77394.1 - 0.00042 20.9 0.0 0.43 11.2 0.0 2.3 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 CDO77394.1 - 0.0063 16.9 0.6 0.24 11.9 0.2 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CDO77394.1 - 0.0072 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CDO77394.1 - 0.0099 15.6 0.7 1 9.2 0.1 2.9 2 1 1 3 3 3 1 Leucine rich repeat UBA_4 PF14555.6 CDO77394.1 - 0.022 14.6 0.3 0.048 13.5 0.3 1.6 1 0 0 1 1 1 0 UBA-like domain Exo_endo_phos_2 PF14529.6 CDO77395.1 - 4.4e-06 26.5 0.2 8.5e-06 25.6 0.2 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDO77395.1 - 0.00018 21.1 1.0 0.00039 20.0 1.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thiamine_BP PF01910.17 CDO77395.1 - 0.025 14.5 0.1 0.078 12.9 0.1 1.8 1 0 0 1 1 1 0 Thiamine-binding protein Prenyltrans PF00432.21 CDO77395.1 - 0.043 13.5 1.3 0.1 12.3 1.3 1.7 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat zf-CCHC PF00098.23 CDO77395.1 - 0.33 11.1 4.7 2.3 8.5 1.9 2.8 2 0 0 2 2 2 0 Zinc knuckle MscS_porin PF12795.7 CDO77395.1 - 0.51 9.8 3.1 0.93 9.0 3.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain RPN7 PF10602.9 CDO77396.1 - 2.4e-38 131.6 0.6 8.3e-38 129.8 0.6 2.0 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CDO77396.1 - 2e-17 63.6 1.3 7.9e-17 61.7 0.7 2.3 2 0 0 2 2 2 1 PCI domain Abhydrolase_1 PF00561.20 CDO77396.1 - 0.00029 20.6 0.0 0.00076 19.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold TPR_2 PF07719.17 CDO77396.1 - 0.0008 19.3 0.1 2.3 8.5 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CDO77396.1 - 0.0031 17.3 0.2 0.47 10.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDO77396.1 - 0.0047 17.2 0.2 0.11 12.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2119 PF09892.9 CDO77396.1 - 0.0083 15.5 0.8 0.023 14.1 0.8 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2119) TPR_7 PF13176.6 CDO77396.1 - 0.012 15.6 0.0 0.85 9.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 CDO77396.1 - 0.11 12.5 0.8 0.29 11.1 0.5 1.9 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family MAS20 PF02064.15 CDO77396.1 - 0.77 9.9 3.2 1.6 8.8 0.1 2.8 3 0 0 3 3 3 0 MAS20 protein import receptor Pro_isomerase PF00160.21 CDO77397.1 - 3.5e-28 98.9 0.0 6e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DDE_3 PF13358.6 CDO77397.1 - 1.1e-10 41.4 2.5 1.2e-10 41.3 0.9 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease U71 PF17474.2 CDO77397.1 - 0.11 12.5 0.2 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Tegument protein UL11 homolog LexA_DNA_bind PF01726.16 CDO77397.1 - 0.18 11.6 0.1 0.39 10.5 0.1 1.5 1 0 0 1 1 1 0 LexA DNA binding domain AMP-binding PF00501.28 CDO77398.1 - 5.4e-26 91.2 0.0 6.2e-25 87.6 0.0 2.4 3 0 0 3 3 3 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CDO77398.1 - 1e-25 90.4 0.0 1.6e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CDO77398.1 - 6e-09 35.7 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CDO77398.1 - 0.004 16.2 0.0 0.0093 15.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 CDO77398.1 - 0.0059 16.9 0.0 0.018 15.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 CDO77398.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CDO77398.1 - 0.12 11.4 0.0 4.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 CDO77399.1 - 8.6e-23 80.7 0.0 1.9e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CDO77399.1 - 3.1e-17 62.4 0.0 6.2e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 CDO77399.1 - 6.5e-10 40.2 0.0 1.9e-09 38.7 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 CDO77399.1 - 0.0014 18.9 0.0 0.0043 17.3 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain ProQ_C PF17516.2 CDO77399.1 - 0.01 15.2 0.1 0.023 14.1 0.1 1.6 1 0 0 1 1 1 0 ProQ C-terminal domain PALP PF00291.25 CDO77399.1 - 0.021 14.3 0.2 0.032 13.6 0.2 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF2855 PF11017.8 CDO77399.1 - 0.035 13.9 0.2 0.16 11.7 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2855) ELFV_dehydrog PF00208.21 CDO77399.1 - 0.036 13.8 0.3 0.057 13.1 0.3 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CAP59_mtransfer PF11735.8 CDO77401.1 - 2.5e-69 233.7 0.0 3.2e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ribosomal_L31e PF01198.19 CDO77402.1 - 1.4e-41 140.6 1.3 1.8e-41 140.3 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 CDO77402.1 - 0.067 13.2 0.0 0.09 12.8 0.0 1.3 1 1 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein CFEM PF05730.11 CDO77403.1 - 1e-09 38.3 12.5 1.5e-09 37.8 12.5 1.2 1 0 0 1 1 1 1 CFEM domain Sporozoite_P67 PF05642.11 CDO77403.1 - 1.3 7.0 11.7 1.6 6.7 11.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VIT1 PF01988.19 CDO77405.1 - 1.1e-30 107.1 0.4 1.3e-30 106.9 0.4 1.1 1 0 0 1 1 1 1 VIT family Isy1 PF06246.12 CDO77407.1 - 3.1e-76 256.3 0.1 3.8e-76 256.0 0.1 1.1 1 0 0 1 1 1 1 Isy1-like splicing family ADPrib_exo_Tox PF03496.14 CDO77407.1 - 0.1 11.9 0.3 0.16 11.3 0.3 1.3 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Sugar_tr PF00083.24 CDO77411.1 - 2.1e-107 359.8 23.4 2.4e-107 359.6 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO77411.1 - 3.1e-28 98.7 28.4 3.1e-28 98.7 28.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO77411.1 - 1.9e-07 29.9 3.7 1.9e-07 29.9 3.7 2.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CDO77411.1 - 0.0013 17.3 5.7 0.0043 15.5 2.0 2.5 2 1 0 2 2 2 1 Transmembrane secretion effector Ribosomal_L41 PF05162.13 CDO77411.1 - 3 8.0 4.7 5.6 7.1 4.7 1.4 1 0 0 1 1 1 0 Ribosomal protein L41 PT-VENN PF04829.13 CDO77411.1 - 4.5 7.4 5.3 1.2 9.3 1.0 2.4 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif AMP-binding PF00501.28 CDO77413.1 - 9.3e-31 106.8 0.0 8.7e-30 103.7 0.0 2.0 1 1 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CDO77413.1 - 6.1e-26 91.1 0.0 1.1e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CDO77413.1 - 4e-08 33.0 0.0 7.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CDO77413.1 - 0.00065 20.0 0.1 0.0018 18.6 0.1 1.8 1 1 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 CDO77413.1 - 0.063 12.4 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein JAB PF01398.21 CDO77414.1 - 1.5e-15 57.2 0.0 3.5e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CDO77414.1 - 4.2e-06 26.5 0.0 4.2e-06 26.5 0.0 2.9 3 1 0 3 3 3 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.11 CDO77414.1 - 2.5e-05 24.4 0.1 6.4e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 USP8 dimerisation domain Borrelia_P83 PF05262.11 CDO77414.1 - 0.012 14.2 9.3 0.016 13.7 9.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4329 PF14220.6 CDO77414.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) Glyco_transf_90 PF05686.12 CDO77415.1 - 7.1e-14 51.5 3.0 1.2e-11 44.1 1.9 3.7 3 1 0 3 3 3 2 Glycosyl transferase family 90 Molybdopterin PF00384.22 CDO77417.1 - 3.8e-69 233.7 0.0 2e-68 231.4 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.9 CDO77417.1 - 1.6e-17 62.7 0.2 1.6e-17 62.7 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 CDO77417.1 - 2.4e-17 63.3 0.1 5.9e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2_4 PF13510.6 CDO77417.1 - 2.2e-11 43.6 0.1 6.2e-11 42.2 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 CDO77417.1 - 0.046 13.4 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 CDO77417.1 - 0.1 12.5 1.1 4.6 7.2 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 CDO77417.1 - 0.46 10.7 2.5 0.64 10.2 1.1 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain N2227 PF07942.12 CDO77418.1 - 2.2e-82 276.3 0.0 6.8e-82 274.7 0.0 1.7 1 1 0 1 1 1 1 N2227-like protein RLL PF10036.9 CDO77418.1 - 0.11 12.3 0.9 0.22 11.3 0.9 1.6 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein SelP_N PF04592.14 CDO77418.1 - 3.7 6.9 14.3 6 6.2 14.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ABC2_membrane PF01061.24 CDO77419.1 - 1.6e-76 256.4 64.5 8e-44 149.6 20.4 3.1 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 CDO77419.1 - 3.9e-40 137.5 0.0 1e-18 68.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CDO77419.1 - 2.7e-33 113.7 15.0 4.7e-30 103.3 0.1 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CDO77419.1 - 1.1e-16 61.2 0.1 2.4e-16 60.1 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CDO77419.1 - 9.8e-08 32.6 0.1 0.0015 18.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CDO77419.1 - 1e-06 28.8 0.0 0.00011 22.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CDO77419.1 - 1.1e-05 25.7 0.0 0.17 12.1 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 CDO77419.1 - 3.9e-05 23.3 0.7 0.24 11.2 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.6 CDO77419.1 - 6.8e-05 22.5 0.0 0.002 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CDO77419.1 - 0.0001 22.5 0.1 0.52 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CDO77419.1 - 0.00012 22.7 0.0 0.73 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CDO77419.1 - 0.00044 20.3 0.2 1 9.4 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 CDO77419.1 - 0.0012 19.1 0.6 1.4 9.2 0.5 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CDO77419.1 - 0.0017 18.3 0.2 0.72 9.8 0.0 3.0 3 0 0 3 3 3 1 NACHT domain SMC_N PF02463.19 CDO77419.1 - 0.0045 16.5 0.1 0.14 11.6 0.0 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 CDO77419.1 - 0.013 14.7 45.0 0.07 12.2 18.3 2.7 2 1 0 2 2 2 0 ABC-2 family transporter protein cobW PF02492.19 CDO77419.1 - 0.023 14.3 1.5 1.8 8.1 0.6 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CDO77419.1 - 0.04 13.7 0.2 6.1 6.6 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 CDO77419.1 - 0.044 13.6 0.3 5.8 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 CDO77419.1 - 0.052 14.0 0.1 18 5.8 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 CDO77419.1 - 0.06 13.6 0.0 6.6 7.0 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CDO77419.1 - 0.064 12.5 0.1 1.3 8.2 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 CDO77419.1 - 0.1 13.1 0.2 0.3 11.6 0.1 1.7 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 CDO77419.1 - 0.11 12.4 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 CDO77419.1 - 0.14 12.2 0.1 7 6.7 0.3 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CDO77419.1 - 0.18 11.5 4.6 2.2 7.9 0.8 2.9 3 0 0 3 3 2 0 AAA domain Chitin_synth_2 PF03142.15 CDO77420.1 - 6.4e-237 787.3 0.4 9.5e-237 786.8 0.4 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CDO77420.1 - 1.4e-140 469.7 0.0 1.9e-139 466.0 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 CDO77420.1 - 4.2e-19 68.2 0.3 1.7e-18 66.3 0.8 1.9 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 CDO77420.1 - 4.4e-12 46.0 0.2 4.2e-08 33.2 0.0 3.2 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 CDO77420.1 - 2e-11 44.2 0.0 2.3e-10 40.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CDO77420.1 - 2.4e-11 43.9 5.5 2.4e-11 43.9 5.5 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CDO77420.1 - 0.0026 17.6 0.0 0.33 10.7 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CDO77420.1 - 0.29 10.6 0.8 1.5 8.3 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferase family 21 DDE_3 PF13358.6 CDO77421.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Cu-oxidase_3 PF07732.15 CDO77422.1 - 4.4e-40 136.4 5.1 7.1e-39 132.5 3.1 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 CDO77422.1 - 6.5e-33 114.1 0.0 1.3e-32 113.1 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CDO77422.1 - 3e-27 95.0 9.3 3.6e-25 88.3 0.7 3.3 2 2 0 2 2 2 2 Multicopper oxidase Phosphoesterase PF04185.14 CDO77423.1 - 1.3e-30 106.9 4.3 5.1e-30 104.9 4.3 1.8 1 1 0 1 1 1 1 Phosphoesterase family Serglycin PF04360.12 CDO77423.1 - 0.084 12.8 3.3 0.2 11.6 3.3 1.6 1 0 0 1 1 1 0 Serglycin ABC_membrane PF00664.23 CDO77424.1 - 1.4e-83 280.7 18.5 7.2e-42 143.9 1.9 2.3 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDO77424.1 - 1.3e-65 220.1 0.0 3.6e-31 108.5 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 CDO77424.1 - 3.1e-15 56.2 6.2 6.4e-06 25.8 0.8 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDO77424.1 - 5.2e-09 36.7 5.2 0.00022 21.7 0.1 3.2 3 1 0 3 3 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CDO77424.1 - 2.1e-08 33.4 0.4 0.0029 16.5 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 CDO77424.1 - 4.1e-08 33.4 0.0 0.86 9.4 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CDO77424.1 - 6.2e-08 33.0 2.3 0.04 14.2 0.1 4.2 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CDO77424.1 - 3.5e-07 30.1 0.1 0.69 9.6 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF87 PF01935.17 CDO77424.1 - 3.7e-07 30.5 0.3 0.012 15.7 0.0 2.7 2 1 0 2 2 2 2 Helicase HerA, central domain Zeta_toxin PF06414.12 CDO77424.1 - 8.9e-07 28.4 0.0 0.016 14.5 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_33 PF13671.6 CDO77424.1 - 2.5e-06 27.7 0.3 0.089 12.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CDO77424.1 - 4.2e-06 26.4 0.1 0.071 12.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDO77424.1 - 7.9e-06 25.9 0.0 0.17 11.8 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 CDO77424.1 - 1.5e-05 25.0 0.1 0.67 10.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CDO77424.1 - 2.4e-05 24.2 0.0 0.2 11.4 0.0 3.4 3 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 CDO77424.1 - 2.7e-05 24.3 0.7 0.69 10.2 0.0 3.7 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 CDO77424.1 - 3.2e-05 23.6 0.2 0.36 10.4 0.0 4.4 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.6 CDO77424.1 - 4.4e-05 24.0 0.0 0.51 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CDO77424.1 - 9.2e-05 22.3 0.0 0.32 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 CDO77424.1 - 0.0004 20.7 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 CDO77424.1 - 0.0009 19.5 3.3 1.4 9.1 0.0 4.2 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CDO77424.1 - 0.0012 18.2 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CDO77424.1 - 0.0015 18.5 0.1 0.89 9.5 0.0 3.1 2 0 0 2 2 2 1 NACHT domain G-alpha PF00503.20 CDO77424.1 - 0.0015 17.8 0.0 0.28 10.3 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA PF00004.29 CDO77424.1 - 0.0021 18.5 0.4 2.7 8.4 0.0 4.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CDO77424.1 - 0.0039 16.4 0.1 1.1 8.4 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain APS_kinase PF01583.20 CDO77424.1 - 0.0039 17.1 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_23 PF13476.6 CDO77424.1 - 0.0059 17.1 0.3 11 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 CDO77424.1 - 0.0095 15.7 0.0 0.46 10.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family TniB PF05621.11 CDO77424.1 - 0.015 14.7 0.0 22 4.4 0.0 3.8 4 0 0 4 4 4 0 Bacterial TniB protein Sigma54_activ_2 PF14532.6 CDO77424.1 - 0.023 14.8 0.1 9.4 6.3 0.0 3.0 3 0 0 3 3 2 0 Sigma-54 interaction domain CbiA PF01656.23 CDO77424.1 - 0.031 14.3 0.1 13 5.8 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 CDO77424.1 - 0.031 14.0 0.0 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDO77424.1 - 0.06 12.9 0.0 9.6 5.7 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CDO77424.1 - 0.06 13.4 0.0 22 5.2 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase PhoH PF02562.16 CDO77424.1 - 0.08 12.4 0.3 12 5.2 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein ATPase PF06745.13 CDO77424.1 - 0.08 12.3 0.1 16 4.8 0.0 2.6 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 CDO77424.1 - 0.086 13.3 0.0 9 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CDO77424.1 - 0.14 11.7 0.0 24 4.5 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 CDO77424.1 - 0.15 12.4 0.2 46 4.3 0.1 3.3 3 1 0 3 3 2 0 AAA domain F-box-like PF12937.7 CDO77425.1 - 5.1e-10 39.1 0.7 5.1e-10 39.1 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDO77425.1 - 0.0058 16.5 0.6 0.028 14.3 0.6 2.3 1 1 0 1 1 1 1 F-box domain PTPA PF03095.15 CDO77426.1 - 3.8e-126 420.6 0.0 4.5e-126 420.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Retrotrans_gag PF03732.17 CDO77426.1 - 0.13 12.6 0.0 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein SURF6 PF04935.12 CDO77427.1 - 3.5e-46 157.5 44.6 3.5e-46 157.5 44.6 2.8 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 CDO77427.1 - 4.3e-21 75.3 10.5 4.3e-21 75.3 10.5 5.8 4 2 2 6 6 6 1 60S ribosome biogenesis protein Rrp14 PAP2 PF01569.21 CDO77428.1 - 1.5e-12 47.4 7.0 1.5e-12 47.4 7.0 2.9 3 0 0 3 3 3 1 PAP2 superfamily Cation_efflux PF01545.21 CDO77428.1 - 6.6e-06 26.0 0.8 6.6e-06 26.0 0.8 2.0 2 0 0 2 2 2 1 Cation efflux family DUF212 PF02681.14 CDO77428.1 - 0.0054 16.9 0.1 0.027 14.6 0.0 2.2 2 0 0 2 2 2 1 Divergent PAP2 family Glyco_hydro_38N PF01074.22 CDO77429.1 - 0.5 9.7 2.8 0.52 9.6 1.4 1.7 1 1 1 2 2 2 0 Glycosyl hydrolases family 38 N-terminal domain DUF4085 PF13315.6 CDO77429.1 - 6.7 6.3 10.2 0.12 12.0 1.8 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4085) BROMI PF14961.6 CDO77429.1 - 9.2 3.5 6.6 13 3.0 6.6 1.1 1 0 0 1 1 1 0 Broad-minded protein GPI-anchored PF10342.9 CDO77432.1 - 1.2e-07 32.4 0.0 1.2e-07 32.4 0.0 3.1 3 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-rbx1 PF12678.7 CDO77433.1 - 4.3e-24 84.6 13.1 6.4e-24 84.0 13.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CDO77433.1 - 1.4e-16 60.3 9.4 1.8e-16 59.9 9.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CDO77433.1 - 7e-06 26.3 15.0 0.00024 21.3 15.0 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDO77433.1 - 0.0012 18.7 11.8 0.024 14.5 11.8 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDO77433.1 - 0.0015 18.3 14.6 0.0019 18.0 9.1 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CDO77433.1 - 0.14 12.3 8.9 0.9 9.8 9.3 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 CDO77433.1 - 0.22 11.4 10.8 0.68 9.8 4.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO77433.1 - 0.26 11.4 7.1 0.86 9.7 7.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CDO77433.1 - 0.37 10.5 14.1 0.14 11.8 4.4 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CDO77433.1 - 1.6 8.5 17.0 87 3.0 17.0 2.4 1 1 0 1 1 1 0 RING-like zinc finger TBCC PF07986.12 CDO77434.1 - 8.8e-22 77.1 0.7 1.6e-21 76.2 0.7 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 CDO77434.1 - 5.1e-11 43.0 1.7 7.9e-11 42.4 1.7 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain DUF4023 PF13215.6 CDO77434.1 - 0.0056 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4023) F-box-like PF12937.7 CDO77435.1 - 0.04 13.8 3.5 0.062 13.2 0.5 2.8 2 0 0 2 2 2 0 F-box-like STAG PF08514.11 CDO77437.1 - 8e-38 128.8 0.5 3.5e-37 126.8 0.3 2.3 1 1 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 CDO77437.1 - 0.00025 21.4 5.4 0.024 15.0 0.9 4.7 4 1 1 5 5 5 2 HEAT repeats DUF4200 PF13863.6 CDO77437.1 - 0.6 10.5 7.5 0.44 11.0 5.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CRC_subunit PF08624.10 CDO77438.1 - 7.1e-12 45.9 0.0 1.1e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit LPD39 PF18858.1 CDO77439.1 - 0.1 12.7 0.3 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 SAP PF02037.27 CDO77441.1 - 4.3e-06 26.3 0.6 1e-05 25.1 0.6 1.6 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.13 CDO77441.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 LETM1-like protein Hamartin PF04388.12 CDO77441.1 - 9.4 4.8 20.5 20 3.7 20.5 1.6 1 0 0 1 1 1 0 Hamartin protein TIMELESS PF04821.14 CDO77442.1 - 5.9e-85 284.9 0.0 5.9e-85 284.9 0.0 2.3 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 CDO77442.1 - 1.6e-06 27.6 0.0 1.6e-06 27.6 0.0 3.5 3 0 0 3 3 3 1 Timeless protein C terminal region AMP-binding PF00501.28 CDO77444.1 - 2e-96 323.2 0.1 2.8e-96 322.7 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CDO77444.1 - 5.5e-25 88.1 0.3 2.4e-24 86.1 0.1 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CDO77444.1 - 3e-15 55.9 0.2 1.1e-14 54.1 0.2 2.1 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF2461 PF09365.10 CDO77445.1 - 5.4e-58 196.4 0.0 9.5e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) BDHCT_assoc PF16204.5 CDO77445.1 - 5.1 6.7 14.8 0.02 14.6 4.9 2.0 3 0 0 3 3 3 0 BDHCT-box associated domain on Bloom syndrome protein Peroxin-3 PF04882.12 CDO77446.1 - 7.7e-113 378.0 0.3 1.2e-112 377.4 0.3 1.3 1 0 0 1 1 1 1 Peroxin-3 GFO_IDH_MocA PF01408.22 CDO77448.1 - 4.5e-14 53.3 0.2 7e-14 52.7 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 CDO77448.1 - 0.019 15.6 0.4 0.032 14.9 0.4 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Glyco_hydro_1 PF00232.18 CDO77449.1 - 4.6e-146 486.8 0.2 6.5e-83 278.7 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 DUF1843 PF08898.10 CDO77450.1 - 0.16 12.5 0.5 0.35 11.4 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) PI-PLC-X PF00388.19 CDO77451.1 - 1.4e-52 177.1 0.0 3.1e-52 176.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CDO77451.1 - 5.2e-44 149.3 0.0 1.2e-43 148.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CDO77451.1 - 3.1e-07 30.6 0.0 4.3e-06 27.0 0.0 2.8 2 1 0 2 2 2 1 C2 domain EF-hand_7 PF13499.6 CDO77451.1 - 4.9e-05 23.7 6.4 0.00098 19.5 0.8 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_like PF09279.11 CDO77451.1 - 5.3e-05 23.6 0.0 0.011 16.2 0.0 2.6 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like PH_14 PF17787.1 CDO77451.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 CDO77451.1 - 0.0022 17.4 3.5 0.035 13.7 0.3 2.9 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.6 CDO77451.1 - 0.017 15.0 0.2 0.045 13.6 0.2 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 CDO77451.1 - 0.35 10.9 8.5 1.8 8.7 0.7 3.7 3 0 0 3 3 3 0 EF-hand domain PAS PF00989.25 CDO77452.1 - 0.023 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold RVT_1 PF00078.27 CDO77453.1 - 7e-22 78.0 0.0 1.5e-21 77.0 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO77453.1 - 2.3e-07 31.1 0.0 5.3e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO77453.1 - 0.0017 19.0 0.0 0.0036 18.0 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_3 PF13358.6 CDO77454.1 - 2e-09 37.4 0.0 3.7e-09 36.5 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 CDO77455.1 - 3.2e-10 40.0 0.7 4.1e-10 39.6 0.6 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF5446 PF17522.2 CDO77456.1 - 0.077 13.2 1.1 0.14 12.4 1.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Exo_endo_phos_2 PF14529.6 CDO77457.1 - 0.0023 17.8 0.1 0.0094 15.8 0.0 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Retrotran_gag_2 PF14223.6 CDO77458.1 - 1.5e-12 47.3 0.1 2.2e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 CDO77458.1 - 0.23 11.2 1.4 0.62 9.8 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF4219 PF13961.6 CDO77458.1 - 0.25 11.1 1.1 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Transposase_21 PF02992.14 CDO77460.1 - 3.5e-14 52.6 0.0 6.3e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 CDO77460.1 - 1.5e-06 27.7 0.1 3.4e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1258 PF06869.12 CDO77460.1 - 0.0081 15.7 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF4674 PF15719.5 CDO77460.1 - 0.38 10.8 3.1 0.48 10.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) YkyA PF10368.9 CDO77461.1 - 0.0039 16.9 0.3 0.007 16.1 0.3 1.4 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein Sec34 PF04136.15 CDO77461.1 - 0.098 12.5 2.0 0.74 9.7 0.4 2.2 2 0 0 2 2 2 0 Sec34-like family DUF1664 PF07889.12 CDO77461.1 - 0.18 11.8 0.9 3.8 7.6 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 CDO77461.1 - 0.67 9.7 7.2 0.38 10.6 1.1 2.2 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 CDO77461.1 - 0.7 10.4 11.0 1 9.9 0.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Mod_r PF07200.13 CDO77461.1 - 0.97 9.5 5.0 3.4 7.8 3.9 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Tropomyosin_1 PF12718.7 CDO77461.1 - 2.8 8.1 6.9 1.1 9.5 2.2 2.3 1 1 1 2 2 2 0 Tropomyosin like SlyX PF04102.12 CDO77461.1 - 4 8.1 10.5 20 5.9 0.4 3.4 2 1 1 3 3 3 0 SlyX ABG_transport PF03806.13 CDO77465.1 - 0.072 11.3 0.0 0.082 11.1 0.0 1.0 1 0 0 1 1 1 0 AbgT putative transporter family Sad1_UNC PF07738.13 CDO77466.1 - 2.3e-10 40.6 0.0 1.1e-05 25.5 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal RVT_1 PF00078.27 CDO77469.1 - 1.9e-14 53.7 0.0 3.8e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO77469.1 - 2.7e-09 37.3 0.0 9.9e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 RNase H Exo_endo_phos_2 PF14529.6 CDO77469.1 - 2.4e-05 24.2 0.1 6e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 CDO77469.1 - 6.3e-05 23.6 6.9 0.00041 21.0 0.2 2.9 3 0 0 3 3 3 2 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CDO77469.1 - 0.035 13.6 0.4 0.087 12.3 0.4 1.6 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF5446 PF17522.2 CDO77469.1 - 0.13 12.4 0.6 0.36 11.0 0.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5446) zf-CCHC PF00098.23 CDO77469.1 - 5.8 7.2 15.6 1.3 9.2 2.1 3.7 3 0 0 3 3 3 0 Zinc knuckle MFS_1 PF07690.16 CDO77471.1 - 9.7e-28 97.1 31.7 1.9e-14 53.4 16.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CDO77471.1 - 2.8 6.1 15.1 0.075 11.3 1.7 3.7 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF202 PF02656.15 CDO77471.1 - 7.2 7.1 0.0 7.2 7.1 0.0 5.6 4 1 1 5 5 5 0 Domain of unknown function (DUF202) HSP70 PF00012.20 CDO77472.1 - 3e-79 266.8 8.1 3e-79 266.8 8.1 2.6 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CDO77472.1 - 0.017 13.9 1.4 0.067 12.0 0.1 2.2 2 0 0 2 2 2 0 MreB/Mbl protein BcrAD_BadFG PF01869.20 CDO77472.1 - 0.023 14.2 0.1 0.054 13.0 0.1 1.7 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family V_ATPase_I PF01496.19 CDO77472.1 - 0.082 10.8 3.5 0.13 10.1 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_tail_APC PF16778.5 CDO77472.1 - 2.4 8.1 7.1 0.12 12.3 1.0 2.1 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Ish1 PF10281.9 CDO77473.1 - 2.3e-65 216.6 19.8 3.5e-11 43.2 1.8 7.4 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 CDO77473.1 - 3.9e-09 36.1 2.3 0.0077 15.9 0.0 6.2 7 0 0 7 7 7 2 HeH/LEM domain TryThrA_C PF12319.8 CDO77473.1 - 0.00048 19.7 13.9 0.00048 19.7 13.9 3.5 2 2 0 3 3 3 1 Tryptophan-Threonine-rich plasmodium antigen C terminal HTH_32 PF13565.6 CDO77473.1 - 0.021 15.5 0.1 6.2 7.5 0.0 4.3 2 1 3 5 5 5 0 Homeodomain-like domain RseA_C PF03873.13 CDO77473.1 - 0.021 15.0 0.1 22 5.4 0.0 3.6 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain SAM_2 PF07647.17 CDO77473.1 - 0.081 13.0 8.2 5.9 7.1 0.0 5.2 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) SAP PF02037.27 CDO77473.1 - 0.13 12.0 0.0 34 4.4 0.0 3.5 3 0 0 3 3 3 0 SAP domain DUF4224 PF13986.6 CDO77473.1 - 0.14 12.1 0.4 17 5.4 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4224) NHase_alpha PF02979.16 CDO77473.1 - 0.28 10.5 2.7 12 5.2 0.0 3.4 2 1 3 5 5 5 0 Nitrile hydratase, alpha chain UNC119_bdg PF15435.6 CDO77475.1 - 0.63 9.6 10.7 0.03 13.9 4.1 2.1 2 1 0 2 2 2 0 UNC119-binding protein C5orf30 homologue MGC-24 PF05283.11 CDO77476.1 - 0.0097 16.4 0.1 0.0097 16.4 0.1 2.4 2 1 1 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin SKG6 PF08693.10 CDO77476.1 - 0.71 9.3 5.7 1.7 8.1 5.7 1.6 1 1 0 1 1 1 0 Transmembrane alpha-helix domain WD40 PF00400.32 CDO77477.1 - 2.8e-06 27.9 3.6 0.047 14.6 0.0 5.1 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO77477.1 - 8e-06 26.1 1.1 0.043 14.1 0.1 4.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PTB PF08416.13 CDO77477.1 - 0.071 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine-binding domain DUF2076 PF09849.9 CDO77478.1 - 0.081 13.0 2.0 0.13 12.3 2.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RTX_C PF08339.10 CDO77478.1 - 8.1 6.5 9.9 1.1 9.3 4.5 2.0 2 0 0 2 2 2 0 RTX C-terminal domain HD PF01966.22 CDO77479.1 - 0.00019 21.6 0.0 0.00028 21.1 0.0 1.3 1 0 0 1 1 1 1 HD domain EF1_GNE PF00736.19 CDO77480.1 - 1.5e-32 111.6 0.4 2.8e-32 110.7 0.4 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CDO77480.1 - 1.1e-14 54.5 4.4 1.1e-14 54.5 4.4 2.7 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 CDO77480.1 - 0.016 15.4 0.1 0.061 13.5 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO77480.1 - 0.022 14.8 0.0 0.4 10.7 0.0 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cnd2 PF05786.14 CDO77480.1 - 0.032 12.9 0.9 0.04 12.6 0.9 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 GST_C PF00043.25 CDO77480.1 - 0.094 12.9 1.2 0.68 10.2 0.0 2.7 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain dCMP_cyt_deam_1 PF00383.23 CDO77481.1 - 2.4e-08 33.7 0.1 3e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CDO77481.1 - 0.0029 17.4 0.0 0.0037 17.0 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase BAG PF02179.16 CDO77483.1 - 3.1e-08 33.9 1.3 1.5e-07 31.8 1.3 2.2 1 1 0 1 1 1 1 BAG domain 2OG-FeII_Oxy_2 PF13532.6 CDO77484.1 - 4.5e-07 30.3 0.0 2.7e-06 27.7 0.0 1.8 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily SET PF00856.28 CDO77485.1 - 1.3e-14 54.9 0.0 2.7e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 SET domain HTH_21 PF13276.6 CDO77485.1 - 0.0036 17.4 0.0 0.0092 16.1 0.0 1.7 1 0 0 1 1 1 1 HTH-like domain DUF1221 PF06760.11 CDO77485.1 - 0.12 11.9 0.1 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1221) ABA_GPCR PF12430.8 CDO77486.1 - 1.4e-43 148.7 1.4 1.4e-43 148.7 1.4 2.0 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor MFS_1 PF07690.16 CDO77486.1 - 2.8e-29 102.1 72.7 5.1e-17 61.8 34.3 3.9 2 1 1 3 3 3 2 Major Facilitator Superfamily GPHR_N PF12537.8 CDO77486.1 - 6.5e-17 61.4 0.0 2.9e-16 59.3 0.0 2.3 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Lipase_3 PF01764.25 CDO77486.1 - 0.61 10.0 2.0 0.97 9.3 0.1 2.1 2 0 0 2 2 2 0 Lipase (class 3) G-alpha PF00503.20 CDO77487.1 - 5.5e-95 318.5 0.0 7.2e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CDO77487.1 - 7.1e-12 45.1 0.1 7.2e-08 32.1 0.0 2.6 3 0 0 3 3 3 2 ADP-ribosylation factor family TniB PF05621.11 CDO77487.1 - 0.0039 16.6 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 CDO77487.1 - 0.012 15.8 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CDO77487.1 - 0.032 14.6 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 CDO77487.1 - 0.037 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 CDO77487.1 - 0.048 13.4 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CDO77487.1 - 0.19 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glyco_hydro_16 PF00722.21 CDO77489.1 - 0.00075 19.0 0.1 0.0016 17.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Oxidored_FMN PF00724.20 CDO77491.1 - 4.2e-73 246.5 0.0 2e-51 175.3 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family GPI-anchored PF10342.9 CDO77492.1 - 6e-12 46.2 6.0 6e-12 46.2 6.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GLEYA PF10528.9 CDO77492.1 - 0.54 10.7 3.4 0.68 10.4 0.2 2.5 1 1 2 3 3 3 0 GLEYA domain LRR_8 PF13855.6 CDO77493.1 - 0.019 14.7 3.9 1.7 8.5 0.1 4.2 4 0 0 4 4 4 0 Leucine rich repeat Oxidored_FMN PF00724.20 CDO77494.1 - 2.2e-80 270.5 0.0 2.6e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 CDO77495.1 - 7.9e-79 265.4 0.0 2.2e-60 204.8 0.0 3.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.24 CDO77496.1 - 9.7e-68 229.1 12.1 9.4e-67 225.8 7.0 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CDO77496.1 - 3.2e-15 55.9 22.3 2.6e-10 39.8 6.2 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily GATA PF00320.27 CDO77497.1 - 2.3e-25 87.9 19.5 3.7e-15 55.2 3.3 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 CDO77497.1 - 4.3e-11 42.4 0.3 1e-10 41.2 0.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 CDO77497.1 - 0.022 14.9 5.5 1.8 8.7 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Integrase_Zn PF02022.19 CDO77497.1 - 0.057 13.4 0.2 0.18 11.8 0.2 1.9 1 0 0 1 1 1 0 Integrase Zinc binding domain Auto_anti-p27 PF06677.12 CDO77497.1 - 0.13 12.4 5.7 0.68 10.1 0.8 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 CDO77497.1 - 0.17 11.8 6.0 4.4 7.2 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 CDO77497.1 - 0.44 10.1 7.2 0.46 10.1 0.8 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 CDO77497.1 - 0.89 9.9 2.7 1 9.7 0.8 2.0 2 0 0 2 2 2 0 zinc-ribbon zinc_ribbon_4 PF13717.6 CDO77497.1 - 1.1 9.3 5.0 1.1 9.3 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CDO77497.1 - 1.5 8.3 6.0 3.5 7.2 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 CDO77497.1 - 2.2 8.3 8.9 2.1 8.3 2.1 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Cytochrom_c3_2 PF14537.6 CDO77497.1 - 4.4 7.9 11.3 6.4 7.3 1.9 2.6 1 1 2 3 3 3 0 Cytochrome c3 Elf1 PF05129.13 CDO77497.1 - 6.7 6.8 6.5 4.9 7.3 0.2 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RRN7 PF11781.8 CDO77497.1 - 7.5 6.3 9.3 0.19 11.4 0.9 2.7 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Cytochrom_CIII PF02085.16 CDO77497.1 - 9.7 6.6 8.6 28 5.1 8.6 1.8 1 0 0 1 1 1 0 Class III cytochrome C family Glyco_hydro_2_C PF02836.17 CDO77498.1 - 0.034 13.2 0.1 0.049 12.7 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_79C PF16862.5 CDO77499.1 - 2.2e-21 76.7 0.0 8.6e-21 74.8 0.0 2.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79C PF16862.5 CDO77500.1 - 7e-20 71.8 0.0 2e-19 70.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79C PF16862.5 CDO77501.1 - 2.9e-14 53.8 1.4 1.3e-13 51.7 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain M157 PF11624.8 CDO77501.1 - 0.098 12.0 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 MHC class I-like protein M157 Plavaka PF18759.1 CDO77502.1 - 5.9e-92 308.4 0.0 1.4e-72 244.7 0.0 2.5 2 1 1 3 3 3 2 Plavaka transposase Pkinase_fungal PF17667.1 CDO77504.1 - 1.3e-19 70.3 0.0 2.2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CDO77504.1 - 0.044 13.1 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF1932 PF09130.11 CDO77504.1 - 0.066 13.2 0.1 0.21 11.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) APH PF01636.23 CDO77504.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDO77504.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_fungal PF17667.1 CDO77505.1 - 2.4e-12 46.4 0.1 5e-12 45.3 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO77506.1 - 2.3e-45 155.1 0.0 2.6e-24 85.8 0.1 3.1 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 CDO77506.1 - 0.091 12.7 0.2 0.26 11.2 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO77507.1 - 1.9e-44 152.1 0.0 1.5e-23 83.3 0.0 3.0 1 1 1 2 2 2 2 Fungal protein kinase MTABC_N PF16185.5 CDO77508.1 - 0.66 9.4 4.7 0.73 9.3 0.1 2.7 2 1 1 3 3 3 0 Mitochondrial ABC-transporter N-terminal five TM region Acetyltransf_3 PF13302.7 CDO77509.1 - 0.0001 23.0 0.0 0.00025 21.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO77509.1 - 0.0052 17.0 0.0 0.009 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Nexin_C PF08628.12 CDO77509.1 - 0.052 14.1 0.2 5.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Sorting nexin C terminal Mif2_N PF15624.6 CDO77509.1 - 0.058 14.1 3.3 0.12 13.1 3.3 1.5 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal EthD PF07110.11 CDO77511.1 - 1.2e-07 32.7 0.2 0.021 15.9 0.1 2.3 2 0 0 2 2 2 2 EthD domain ABM PF03992.16 CDO77511.1 - 0.029 14.5 0.2 0.15 12.2 0.2 2.2 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Thaumatin PF00314.17 CDO77513.1 - 2.7e-69 233.1 6.1 3.2e-69 232.8 6.1 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 CDO77513.1 - 0.04 13.2 1.8 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Beta-1,3-glucanase DUF1275 PF06912.11 CDO77514.1 - 0.0058 16.6 3.1 0.0073 16.2 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1129 PF06570.11 CDO77514.1 - 0.27 10.7 1.5 0.39 10.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) OPT PF03169.15 CDO77515.1 - 4.5e-168 560.7 42.1 5.5e-168 560.4 42.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 CDO77515.1 - 7.7 6.8 7.9 4.3 7.6 3.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Glyco_transf_8 PF01501.20 CDO77516.1 - 5.6e-11 42.5 0.1 1.3e-10 41.3 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 CDO77516.1 - 0.00084 19.4 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase PrkA PF06798.12 CDO77516.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain RSN1_7TM PF02714.15 CDO77517.1 - 9.1e-79 264.6 23.5 9.1e-79 264.6 23.5 1.9 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CDO77517.1 - 4e-40 137.9 0.0 8e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CDO77517.1 - 8.9e-40 136.0 1.8 8.9e-40 136.0 1.8 3.1 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport TMC PF07810.13 CDO77517.1 - 2.5 8.7 13.6 2.6 8.7 4.4 3.0 2 1 1 3 3 3 0 TMC domain TFIIA PF03153.13 CDO77517.1 - 4.7 7.1 13.2 6.8 6.6 13.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0029 PF01205.19 CDO77518.1 - 4.2e-26 91.3 0.0 7e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF5585 PF17823.1 CDO77518.1 - 0.03 13.3 9.4 0.054 12.5 9.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Fib_alpha PF08702.10 CDO77518.1 - 0.12 12.6 0.1 12 6.1 0.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3445 PF11927.8 CDO77519.1 - 1.2e-61 208.2 0.0 1.5e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) LisH PF08513.11 CDO77520.1 - 0.17 11.9 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 LisH HisG PF01634.18 CDO77521.1 - 2.6e-52 177.0 0.2 5e-52 176.1 0.1 1.6 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.11 CDO77521.1 - 7.2e-28 96.6 0.1 1.4e-27 95.6 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain Calpain_III PF01067.22 CDO77521.1 - 4.8e-09 36.6 0.1 0.00045 20.5 0.0 3.6 2 1 0 2 2 2 2 Calpain large subunit, domain III Peptidase_C2 PF00648.21 CDO77521.1 - 1.3e-07 31.0 0.0 2.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.18 CDO77521.1 - 9.6e-07 28.8 4.4 1.7e-06 28.0 4.4 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain NMT1 PF09084.11 CDO77521.1 - 5e-05 23.3 0.1 8.4e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Pkip-1 PF06878.11 CDO77521.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Pkip-1 protein Methyltransf_20 PF12147.8 CDO77521.1 - 0.12 11.6 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Rit1_C PF17184.4 CDO77522.1 - 6e-77 258.8 0.0 3.9e-64 216.7 0.0 2.3 1 1 1 2 2 2 2 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 CDO77522.1 - 1.2e-31 109.2 0.0 2.5e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain SQHop_cyclase_N PF13249.6 CDO77525.1 - 0.089 11.9 0.5 5.9 5.9 0.0 2.0 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_N PF13249.6 CDO77526.1 - 1.7e-06 27.4 0.0 2.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Squalene-hopene cyclase N-terminal domain DUF3602 PF12223.8 CDO77528.1 - 3.9e-15 56.2 17.0 5.9e-06 26.8 5.2 4.4 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) AA_permease_2 PF13520.6 CDO77529.1 - 2.1e-49 168.5 52.9 2.5e-37 128.7 29.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 CDO77529.1 - 1.7e-12 46.7 34.9 2.9e-11 42.7 11.3 2.6 2 1 1 3 3 3 2 Amino acid permease Gln-synt_C PF00120.24 CDO77530.1 - 9.3e-71 238.6 0.0 1.3e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 CDO77530.1 - 0.019 14.8 0.0 0.057 13.2 0.0 1.8 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain Pkinase_fungal PF17667.1 CDO77531.1 - 6.8e-53 179.9 0.0 1.2e-52 179.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO77532.1 - 1.6e-12 46.9 0.0 2e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO77533.1 - 2.9e-12 46.1 0.0 4e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase LRR_4 PF12799.7 CDO77534.1 - 0.005 17.2 0.8 1.8 9.1 0.0 4.3 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) FHA PF00498.26 CDO77535.1 - 1.5e-16 60.5 0.1 5.1e-16 58.8 0.0 1.9 2 0 0 2 2 2 1 FHA domain DUF1664 PF07889.12 CDO77535.1 - 0.00066 19.7 11.6 0.17 12.0 1.3 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF1664) Yop-YscD_cpl PF16697.5 CDO77535.1 - 0.0011 19.2 0.0 0.0043 17.3 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Lipoprotein_7 PF01540.16 CDO77535.1 - 0.022 14.0 1.2 0.026 13.8 0.1 1.6 2 0 0 2 2 2 0 Adhesin lipoprotein AAA_13 PF13166.6 CDO77535.1 - 0.86 8.2 12.6 0.06 12.0 4.8 2.0 2 0 0 2 2 2 0 AAA domain Syntaxin-6_N PF09177.11 CDO77535.1 - 1.7 9.2 11.8 12 6.5 0.8 3.7 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 CDO77535.1 - 2 8.6 8.2 6.2 7.0 0.7 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 CDO77535.1 - 2.3 8.7 11.3 61 4.2 0.3 4.3 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Eno-Rase_NADH_b PF12242.8 CDO77536.1 - 0.17 11.6 0.9 0.32 10.8 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Hamartin PF04388.12 CDO77536.1 - 3 6.4 20.1 3.6 6.1 20.1 1.0 1 0 0 1 1 1 0 Hamartin protein G-patch PF01585.23 CDO77537.1 - 1.5e-08 34.4 0.0 3.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CDO77537.1 - 5.9e-08 32.7 0.1 5.9e-08 32.7 0.1 3.4 2 1 0 2 2 1 1 G-patch domain CENP-N PF05238.13 CDO77537.1 - 0.065 12.5 13.9 0.081 12.2 13.9 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like CDC45 PF02724.14 CDO77537.1 - 0.19 10.0 21.2 0.22 9.8 21.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CDO77537.1 - 0.28 11.0 19.5 0.36 10.6 19.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2828 PF11443.8 CDO77537.1 - 0.57 8.2 10.4 0.74 7.8 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Nop14 PF04147.12 CDO77537.1 - 0.87 7.7 23.7 1 7.5 23.7 1.0 1 0 0 1 1 1 0 Nop14-like family AAA_11 PF13086.6 CDO77537.1 - 1.6 8.4 11.9 2.1 8.1 11.9 1.1 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 CDO77537.1 - 2.4 7.1 13.6 2.8 6.9 13.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Paramyxo_ncap PF00973.19 CDO77537.1 - 2.6 6.9 8.5 3.3 6.5 8.5 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SAPS PF04499.15 CDO77537.1 - 3.2 6.4 15.4 3.7 6.2 15.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 CDO77537.1 - 4.1 7.4 9.8 5.5 7.0 9.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region U79_P34 PF03064.16 CDO77537.1 - 4.4 6.6 22.5 6.1 6.1 22.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Paf1 PF03985.13 CDO77537.1 - 4.6 6.1 22.3 5.9 5.8 22.3 1.2 1 0 0 1 1 1 0 Paf1 FAM60A PF15396.6 CDO77537.1 - 5 7.1 17.5 6.8 6.6 17.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Apt1 PF10351.9 CDO77537.1 - 6.2 5.5 14.5 7.6 5.3 14.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CRT10 PF08728.10 CDO77537.1 - 6.9 4.7 6.6 7.9 4.5 6.6 1.1 1 0 0 1 1 1 0 CRT10 Tim54 PF11711.8 CDO77537.1 - 7.8 5.2 16.6 11 4.6 16.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ALMT PF11744.8 CDO77537.1 - 8.3 5.1 9.5 9.3 5.0 9.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter NARP1 PF12569.8 CDO77537.1 - 8.4 5.2 24.1 11 4.7 24.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4746 PF15928.5 CDO77537.1 - 10 5.5 17.1 12 5.2 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4597 PF15366.6 CDO77538.1 - 0.0097 15.6 0.1 0.074 12.8 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4597) HemY_N PF07219.13 CDO77538.1 - 0.034 14.3 0.6 0.052 13.7 0.6 1.3 1 0 0 1 1 1 0 HemY protein N-terminus DUF4381 PF14316.6 CDO77538.1 - 0.071 13.3 0.1 0.16 12.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4212 PF13937.6 CDO77540.1 - 2.3 8.6 6.8 0.99 9.8 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Ammonium_transp PF00909.21 CDO77542.1 - 2.3e-115 385.5 29.9 2.6e-115 385.3 29.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family FAD_binding_3 PF01494.19 CDO77544.1 - 4.9e-63 213.5 0.0 4.2e-61 207.1 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 CDO77544.1 - 2.8e-06 26.7 0.3 6e-06 25.6 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CDO77544.1 - 9.9e-05 21.7 0.8 0.00021 20.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDO77544.1 - 0.00012 20.9 0.1 0.00021 20.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 CDO77544.1 - 0.00054 19.6 0.0 0.0013 18.4 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDO77544.1 - 0.0007 19.8 0.1 0.0017 18.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CDO77544.1 - 0.0007 18.9 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CDO77544.1 - 0.00075 18.7 0.2 0.0011 18.1 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 CDO77544.1 - 0.001 18.5 0.2 0.0016 17.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CDO77544.1 - 0.0015 17.5 0.0 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 CDO77544.1 - 0.0037 16.6 0.0 0.0061 15.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CDO77544.1 - 0.019 15.5 0.1 0.046 14.3 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CDO77544.1 - 0.043 12.9 0.2 0.1 11.6 0.3 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CDO77544.1 - 0.048 12.9 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CDO77545.1 - 7e-46 157.1 0.0 5.4e-31 108.1 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CDO77545.1 - 0.018 14.3 0.0 0.07 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CDO77546.1 - 5.2e-70 236.4 0.0 7.5e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CDO77546.1 - 4.4e-06 26.1 0.8 0.026 13.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDO77546.1 - 9e-06 25.0 0.6 0.00019 20.7 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 CDO77546.1 - 0.0002 21.9 0.4 0.6 10.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDO77546.1 - 0.0018 17.1 0.4 0.0076 15.0 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 CDO77546.1 - 0.0029 16.5 0.0 0.0054 15.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 CDO77546.1 - 0.0044 16.6 0.2 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CDO77546.1 - 0.0045 16.3 0.3 0.01 15.1 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PKD PF00801.20 CDO77546.1 - 0.036 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 PKD domain Glu_dehyd_C PF16912.5 CDO77546.1 - 0.045 13.2 0.0 11 5.4 0.0 2.8 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 CDO77546.1 - 0.054 12.7 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 CDO77546.1 - 0.062 13.5 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CDO77546.1 - 0.078 12.3 0.4 0.17 11.2 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 CDO77546.1 - 0.086 12.1 0.1 6.9 5.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 CDO77546.1 - 0.1 11.6 0.2 0.17 10.9 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A E1_dh PF00676.20 CDO77547.1 - 1.3e-59 201.7 0.0 1.8e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CDO77547.1 - 4.5e-53 179.0 0.0 1.2e-52 177.6 0.0 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CDO77547.1 - 3.4e-19 68.2 0.4 6.6e-19 67.2 0.4 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus GPI-anchored PF10342.9 CDO77548.1 - 1.4e-08 35.4 0.0 2.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2046 PF09755.9 CDO77549.1 - 0.012 14.9 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) JIP_LZII PF16471.5 CDO77549.1 - 0.026 14.7 0.7 0.047 13.9 0.3 1.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II CCDC144C PF14915.6 CDO77549.1 - 0.026 13.6 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Sec2p PF06428.11 CDO77549.1 - 0.036 14.0 0.1 0.35 10.9 0.0 2.2 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.21 CDO77549.1 - 0.048 13.8 1.5 0.084 13.0 0.5 1.8 2 0 0 2 2 2 0 bZIP transcription factor RRM_8 PF11835.8 CDO77549.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain DivIC PF04977.15 CDO77549.1 - 0.081 12.7 0.4 0.2 11.4 0.2 1.7 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.11 CDO77549.1 - 0.081 13.2 0.4 0.19 12.0 0.1 1.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 HALZ PF02183.18 CDO77549.1 - 0.21 11.9 6.8 0.21 11.8 0.2 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper HR1 PF02185.16 CDO77550.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Hr1 repeat Plavaka PF18759.1 CDO77552.1 - 1.2e-85 287.6 0.0 1.6e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Beach PF02138.18 CDO77555.1 - 5.7e-69 232.6 0.0 4.9e-43 147.5 0.1 2.7 2 1 1 3 3 3 2 Beige/BEACH domain Laminin_G_3 PF13385.6 CDO77555.1 - 2.2e-10 40.9 0.0 4.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 CDO77555.1 - 1.3e-08 34.9 0.1 3.1e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 CDO77555.1 - 5.5e-05 22.6 0.4 5.5e-05 22.6 0.4 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) DUF4800 PF16057.5 CDO77555.1 - 0.03 13.6 1.8 0.063 12.5 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Med25 PF11232.8 CDO77555.1 - 0.13 12.3 0.0 0.45 10.5 0.0 1.9 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 His_Phos_2 PF00328.22 CDO77556.1 - 4e-06 26.4 0.0 4e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) F-box PF00646.33 CDO77558.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 F-box domain Methyltransf_11 PF08241.12 CDO77560.1 - 5e-20 71.9 0.0 8.3e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO77560.1 - 3.7e-17 62.8 0.0 6.8e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO77560.1 - 3.2e-13 49.7 0.0 5e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO77560.1 - 3.8e-09 37.2 0.0 7.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDO77560.1 - 2.9e-06 26.8 0.0 4.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CDO77560.1 - 7.3e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CDO77560.1 - 0.0056 16.6 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 CDO77560.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 CDO77560.1 - 0.057 12.9 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 CDO77560.1 - 0.065 12.5 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Claudin_2 PF13903.6 CDO77561.1 - 5 6.8 15.7 3.4 7.4 2.2 2.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction F-box-like PF12937.7 CDO77562.1 - 0.00017 21.4 0.1 0.0005 19.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like zf-RVT PF13966.6 CDO77562.1 - 0.00065 20.4 0.0 0.0015 19.2 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_3 PF13358.6 CDO77564.1 - 2.6e-10 40.2 0.2 4.9e-10 39.3 0.2 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease F-box-like PF12937.7 CDO77564.1 - 8.1e-06 25.6 0.1 2e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CDO77564.1 - 0.00074 19.3 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain CENP-F_leu_zip PF10473.9 CDO77565.1 - 0.0028 17.7 30.7 0.0028 17.7 30.7 5.7 2 2 4 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.13 CDO77565.1 - 0.046 14.1 25.8 0.28 11.6 1.7 6.8 6 1 0 6 6 6 0 Lipoprotein leucine-zipper TPR_14 PF13428.6 CDO77565.1 - 0.2 12.6 2.3 0.98 10.4 0.3 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HOOK PF05622.12 CDO77565.1 - 7.2 4.6 83.9 0.23 9.6 38.3 3.1 2 1 1 3 3 3 0 HOOK protein Glyco_hydro_76 PF03663.14 CDO77566.1 - 1.8e-11 44.2 11.7 3.2e-11 43.3 11.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Arabinose_trans PF04602.12 CDO77566.1 - 0.032 13.1 1.3 0.046 12.6 1.3 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein Glyco_hydro_76 PF03663.14 CDO77567.1 - 3.9e-16 59.5 2.0 4.6e-16 59.3 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CDO77567.1 - 0.0016 17.6 0.0 0.0019 17.3 0.0 1.2 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 ANAPC4_WD40 PF12894.7 CDO77568.1 - 0.0022 18.2 0.0 0.73 10.2 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CDO77568.1 - 0.032 15.1 0.0 0.82 10.6 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat MoeA_C PF03454.15 CDO77569.1 - 0.05 13.8 0.1 0.08 13.1 0.1 1.3 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Exo70 PF03081.15 CDO77570.1 - 5.4e-47 160.6 0.0 9.2e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit CBFD_NFYB_HMF PF00808.23 CDO77570.1 - 0.068 13.5 0.0 0.75 10.1 0.0 2.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Snapin_Pallidin PF14712.6 CDO77570.1 - 0.11 12.9 1.3 0.29 11.6 1.3 1.7 1 0 0 1 1 1 0 Snapin/Pallidin BLOC1_2 PF10046.9 CDO77570.1 - 3.1 8.2 6.3 29 5.0 1.7 3.2 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RNA_lig_T4_1 PF09511.10 CDO77571.1 - 1.3e-85 286.7 0.0 2.1e-85 286.1 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 CDO77571.1 - 3e-14 53.1 0.0 8.7e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 CDO77571.1 - 8.4e-14 52.0 0.0 1.9e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 CDO77571.1 - 0.12 13.0 0.0 0.62 10.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain UNC-93 PF05978.16 CDO77572.1 - 8e-14 51.6 7.1 8e-14 51.6 7.1 3.0 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 CDO77572.1 - 8.1e-14 51.3 32.2 8.1e-14 51.3 32.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Atg14 PF10186.9 CDO77573.1 - 2.1e-32 112.5 0.1 1e-19 70.8 0.0 2.1 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 CDO77573.1 - 0.0007 20.0 1.6 0.069 13.6 0.0 2.7 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 CDO77573.1 - 0.012 16.0 1.1 1.1 9.7 0.3 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) MCC-bdg_PDZ PF10506.9 CDO77573.1 - 0.044 13.8 2.1 7.8 6.6 0.1 2.4 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Cauli_AT PF03233.13 CDO77573.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Aphid transmission protein Spc29 PF17082.5 CDO77573.1 - 0.067 13.0 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Phlebovirus_NSM PF07246.11 CDO77573.1 - 0.074 12.4 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4407 PF14362.6 CDO77573.1 - 0.094 12.1 0.2 6.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 CDO77573.1 - 0.12 12.6 1.3 2.2 8.5 1.0 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 EzrA PF06160.12 CDO77573.1 - 0.14 10.3 1.4 0.14 10.3 0.4 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 CDO77573.1 - 0.19 10.6 3.9 0.88 8.4 2.7 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 CDO77573.1 - 0.24 11.4 0.4 10 6.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 CDO77573.1 - 0.29 11.4 4.6 0.56 10.5 1.7 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 CheZ PF04344.13 CDO77573.1 - 0.31 10.9 1.4 0.36 10.7 0.6 1.4 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Med9 PF07544.13 CDO77573.1 - 0.33 11.1 2.5 5.1 7.3 1.2 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-B_box PF00643.24 CDO77573.1 - 0.9 9.7 3.7 1.5 9.0 3.7 1.4 1 0 0 1 1 1 0 B-box zinc finger ADIP PF11559.8 CDO77573.1 - 3.2 7.8 7.2 11 6.0 4.1 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 CDO77573.1 - 6.5 6.6 6.4 22 4.9 0.6 2.6 3 0 0 3 3 3 0 Septum formation initiator GST_N_3 PF13417.6 CDO77574.1 - 2.7e-12 46.9 0.0 6.1e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO77574.1 - 3.7e-08 33.6 0.0 7.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO77574.1 - 9.6e-08 32.3 0.1 7.4e-07 29.4 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO77574.1 - 0.025 14.6 0.1 0.066 13.2 0.1 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DDE_Tnp_4 PF13359.6 CDO77576.1 - 1.3e-11 44.5 0.0 1.8e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 CDO77576.1 - 0.0044 16.6 0.1 0.0066 16.1 0.1 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.21 CDO77576.1 - 0.0086 15.7 0.2 0.023 14.4 0.2 1.9 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 CDO77576.1 - 0.024 15.0 0.1 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 CDO77577.1 - 0.00063 20.7 0.2 0.0013 19.6 0.1 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain BTB PF00651.31 CDO77578.1 - 4.7e-05 23.6 0.0 7.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain LRR_8 PF13855.6 CDO77580.1 - 0.053 13.3 0.0 0.22 11.3 0.0 2.1 1 1 0 1 1 1 0 Leucine rich repeat F-box-like PF12937.7 CDO77581.1 - 0.00021 21.1 0.2 0.00089 19.1 0.0 2.2 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 CDO77582.1 - 0.79 10.2 0.1 0.79 10.2 0.1 2.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) CbtA PF09490.10 CDO77587.1 - 0.024 14.4 0.9 0.056 13.2 0.0 2.0 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) Lipase_GDSL_2 PF13472.6 CDO77590.1 - 4.2e-05 24.0 2.4 6.1e-05 23.5 2.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family NIF PF03031.18 CDO77591.1 - 7.1e-41 139.6 0.0 1e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NAD_binding_5 PF07994.12 CDO77593.1 - 9.6e-140 465.5 0.0 1.1e-139 465.3 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CDO77593.1 - 1.9e-44 150.4 0.0 3.1e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase F-box-like PF12937.7 CDO77594.1 - 0.00027 20.8 0.3 0.00081 19.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CDO77594.1 - 0.01 15.7 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 0 F-box domain RhoGAP PF00620.27 CDO77595.1 - 1.8e-39 135.0 0.0 4.5e-39 133.7 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 CDO77595.1 - 5.5e-10 39.7 0.0 3.7e-07 30.5 0.0 3.2 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 CDO77595.1 - 5.1e-08 33.1 0.0 4.1e-07 30.2 0.0 2.6 2 1 0 2 2 2 1 RasGEF N-terminal motif PH PF00169.29 CDO77595.1 - 5.7e-08 33.2 0.0 0.00014 22.3 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 CDO77595.1 - 1.8e-06 28.3 0.0 0.00016 22.0 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain SDA1 PF05285.12 CDO77597.1 - 0.0061 16.0 5.4 0.0086 15.5 5.4 1.1 1 0 0 1 1 1 1 SDA1 DUF4778 PF16008.5 CDO77597.1 - 0.034 14.2 0.9 0.052 13.6 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Nop14 PF04147.12 CDO77597.1 - 0.056 11.7 4.5 0.069 11.4 4.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4355 PF14265.6 CDO77597.1 - 0.33 11.2 8.3 0.6 10.4 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) CDC45 PF02724.14 CDO77597.1 - 2.7 6.2 9.6 3.7 5.7 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2401 PF10287.9 CDO77599.1 - 2.4e-53 181.1 1.4 3.3e-53 180.6 1.4 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CDO77599.1 - 3.9e-19 68.8 0.0 7.8e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Lactamase_B_2 PF12706.7 CDO77600.1 - 2.5e-37 128.4 3.2 1.1e-36 126.2 3.2 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDO77600.1 - 2.7e-13 50.1 0.0 2.9e-09 37.0 0.0 2.3 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CDO77600.1 - 0.019 15.0 0.9 0.29 11.1 0.6 2.7 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CDO77601.1 - 3e-37 128.1 0.6 1.1e-36 126.2 0.6 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CDO77601.1 - 1.9e-13 50.7 0.0 4.8e-12 46.1 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Q_salvage PF10343.9 CDO77602.1 - 4.8e-94 315.1 0.0 6e-94 314.8 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Cpn60_TCP1 PF00118.24 CDO77603.1 - 1.1e-99 334.3 0.3 1.4e-49 169.0 0.1 3.0 2 1 1 3 3 3 3 TCP-1/cpn60 chaperonin family EAL PF00563.20 CDO77603.1 - 0.044 13.3 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 EAL domain Mito_fiss_reg PF05308.11 CDO77604.1 - 1.5 8.9 10.0 2.9 7.9 10.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Plavaka PF18759.1 CDO77605.1 - 3.4e-22 79.1 0.0 2.6e-21 76.2 0.0 2.2 1 1 0 1 1 1 1 Plavaka transposase DUF2401 PF10287.9 CDO77608.1 - 1.3e-48 165.6 1.2 1.7e-48 165.2 1.2 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CDO77608.1 - 1.4e-20 73.5 0.1 2.7e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) rve PF00665.26 CDO77609.1 - 1.5e-16 60.6 0.0 3e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO77609.1 - 6.1e-09 35.6 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain DDE_3 PF13358.6 CDO77609.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF5487 PF17589.2 CDO77609.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5487) Transposase_21 PF02992.14 CDO77612.1 - 4.2e-10 39.2 0.0 5.9e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 CDO77612.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1258) RVT_2 PF07727.14 CDO77614.1 - 1.8e-49 168.6 0.3 2e-49 168.4 0.3 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CDO77615.1 - 5.6e-08 32.5 0.0 6.7e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_4 PF13894.6 CDO77616.1 - 0.12 13.3 1.1 0.37 11.7 1.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CDO77616.1 - 0.42 11.2 3.8 0.13 12.7 0.8 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4939 PF16297.5 CDO77617.1 - 4.7e-11 42.5 0.0 8.1e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 CDO77617.1 - 0.089 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein DUF3892 PF13031.6 CDO77619.1 - 0.013 16.1 0.0 0.028 15.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) Mito_carr PF00153.27 CDO77620.1 - 1.3e-40 137.2 1.5 3.2e-16 59.0 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein HGTP_anticodon PF03129.20 CDO77621.1 - 5.3e-21 74.6 0.0 1.2e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CDO77621.1 - 3.9e-10 40.0 0.0 1.1e-09 38.5 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) APH PF01636.23 CDO77622.1 - 0.014 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_RI_capping PF18779.1 CDO77624.1 - 0.021 14.5 0.2 0.055 13.1 0.2 1.7 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat PIEZO PF15917.5 CDO77624.1 - 0.091 12.2 4.1 0.062 12.8 1.5 1.8 2 0 0 2 2 2 0 Piezo CCDC71L PF15374.6 CDO77624.1 - 0.39 9.9 1.9 0.49 9.6 1.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L 5_nucleotid PF05761.14 CDO77624.1 - 2.3 7.1 4.5 3.8 6.3 4.5 1.3 1 0 0 1 1 1 0 5' nucleotidase family AC_N PF16214.5 CDO77625.1 - 0.35 10.0 3.6 0.47 9.5 3.6 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Methyltransf_2 PF00891.18 CDO77626.1 - 2.1e-11 43.5 0.0 3.7e-11 42.7 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 CDO77626.1 - 0.028 14.3 0.0 0.057 13.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain ubiquitin PF00240.23 CDO77627.1 - 3.3e-68 225.4 8.8 3.8e-34 116.2 0.5 3.0 2 1 1 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 CDO77627.1 - 6.8e-30 102.7 6.6 9e-16 57.5 0.6 2.6 2 1 1 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CDO77627.1 - 1.1e-12 48.2 1.4 9e-05 22.9 0.1 3.3 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 CDO77627.1 - 4.1e-08 33.0 0.1 0.012 15.6 0.0 2.4 2 1 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CDO77627.1 - 5e-08 33.2 0.3 0.012 15.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CDO77627.1 - 3e-07 30.5 0.2 0.038 14.1 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CDO77627.1 - 2.8e-06 27.8 0.1 0.098 13.2 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain HATPase_c PF02518.26 CDO77627.1 - 0.00023 21.7 1.7 0.4 11.2 0.2 2.1 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ubiquitin_4 PF18036.1 CDO77627.1 - 0.00043 20.3 6.6 6.4 6.9 0.2 4.0 4 0 0 4 4 4 1 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 CDO77627.1 - 0.0011 18.8 0.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain DUF3861 PF12977.7 CDO77627.1 - 0.0018 18.4 0.3 1.5 9.0 0.0 2.3 1 1 1 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 CDO77627.1 - 0.0039 17.9 0.1 2.1 9.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial Ig domain ACT_5 PF13710.6 CDO77627.1 - 0.0089 15.8 0.3 5.6 6.9 0.1 2.4 2 0 0 2 2 2 2 ACT domain DUF2870 PF11069.8 CDO77627.1 - 0.017 15.5 0.0 12 6.3 0.0 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2870) TmoB PF06234.12 CDO77627.1 - 0.03 14.4 0.6 12 6.1 0.1 2.7 2 2 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) PDGLE PF13190.6 CDO77627.1 - 0.035 14.0 0.6 5 7.1 0.1 2.6 1 1 1 2 2 2 0 PDGLE domain DUF493 PF04359.14 CDO77627.1 - 0.059 14.0 0.0 5.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF493) ACT_4 PF13291.6 CDO77627.1 - 0.081 13.5 0.0 17 6.1 0.0 2.3 2 0 0 2 2 2 0 ACT domain FlgD_ig PF13860.6 CDO77627.1 - 0.13 12.2 2.0 12 5.9 0.2 2.5 2 0 0 2 2 2 0 FlgD Ig-like domain Tash_PEST PF07708.11 CDO77627.1 - 0.21 11.8 9.6 3.1 8.1 1.5 2.4 2 0 0 2 2 2 0 Tash protein PEST motif FERM_f0 PF16511.5 CDO77627.1 - 0.31 11.4 1.1 50 4.3 0.1 3.2 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM Plexin_cytopl PF08337.12 CDO77627.1 - 0.8 8.3 5.2 9.2 4.8 0.3 3.1 2 1 1 3 3 3 0 Plexin cytoplasmic RasGAP domain Peroxidase_ext PF11895.8 CDO77628.1 - 1.2e-25 89.2 1.2 2.7e-25 88.1 1.2 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 CDO77628.1 - 4.5e-21 75.6 0.0 6.7e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase p450 PF00067.22 CDO77629.1 - 8.8e-61 206.1 0.0 3.9e-59 200.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 AC_N PF16214.5 CDO77630.1 - 0.98 8.5 3.5 1.6 7.8 3.5 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region EB PF01683.18 CDO77631.1 - 0.0027 18.0 24.6 0.041 14.2 0.2 4.2 3 2 1 4 4 4 3 EB module Dickkopf_N PF04706.12 CDO77631.1 - 0.018 15.5 7.5 0.018 15.5 7.5 4.4 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region Motilin_ghrelin PF04644.12 CDO77631.1 - 2.8 7.8 4.4 11 5.9 0.1 2.4 2 0 0 2 2 2 0 Motilin/ghrelin DAO PF01266.24 CDO77632.1 - 1.2e-07 31.6 0.1 4.8e-05 23.1 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CDO77632.1 - 1.7e-07 31.3 0.0 6.9e-07 29.4 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CDO77632.1 - 4.4e-06 26.0 0.8 8.2e-05 21.9 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CDO77632.1 - 1.2e-05 24.7 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CDO77632.1 - 2.4e-05 23.7 0.0 0.00062 19.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 CDO77632.1 - 0.00011 21.0 0.4 0.00017 20.4 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 CDO77632.1 - 0.00015 21.2 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CDO77632.1 - 0.00016 21.0 0.3 0.00025 20.4 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO77632.1 - 0.00024 21.1 0.0 0.00047 20.2 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CDO77632.1 - 0.0023 17.1 0.2 0.0037 16.4 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 CDO77632.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 CDO77632.1 - 0.054 12.6 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 CDO77632.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 CDO77632.1 - 0.12 11.2 0.0 0.31 9.9 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 CDO77632.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.18 CDO77633.1 - 1e-29 103.4 0.0 1.9e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NUC130_3NT PF08158.12 CDO77633.1 - 1.9 8.9 3.5 24 5.3 0.0 3.0 3 0 0 3 3 3 0 NUC130/3NT domain Sec7 PF01369.20 CDO77634.1 - 5e-31 107.8 0.0 7e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain FixG_C PF11614.8 CDO77634.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase PH PF00169.29 CDO77634.1 - 0.043 14.3 0.0 0.53 10.8 0.0 2.4 2 0 0 2 2 2 0 PH domain CHCH PF06747.13 CDO77635.1 - 3.5e-06 27.0 5.1 6.4e-06 26.2 5.1 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 CDO77635.1 - 0.18 12.3 1.9 0.31 11.5 1.9 1.3 1 0 0 1 1 1 0 GCK domain SPX PF03105.19 CDO77636.1 - 0.78 9.6 3.3 0.98 9.3 3.3 1.2 1 0 0 1 1 1 0 SPX domain Sporozoite_P67 PF05642.11 CDO77636.1 - 2.7 6.0 7.1 3.2 5.7 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 CDO77636.1 - 6.4 4.8 12.8 9.4 4.3 12.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BUD22 PF09073.10 CDO77637.1 - 0.59 9.4 7.3 0.94 8.7 7.3 1.3 1 0 0 1 1 1 0 BUD22 DUF347 PF03988.12 CDO77637.1 - 2.2 8.6 7.3 0.68 10.2 1.1 3.0 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) E1-E2_ATPase PF00122.20 CDO77638.1 - 2.8e-32 111.7 0.0 7.5e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 CDO77638.1 - 6.4e-25 87.7 0.0 1.3e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 CDO77638.1 - 1e-18 68.4 0.1 7.6e-09 36.2 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 CDO77638.1 - 6.1e-07 29.3 6.3 6.1e-07 29.3 6.3 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CDO77638.1 - 1.5e-05 25.0 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CDO77638.1 - 0.00018 21.1 0.0 0.00039 20.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ssl1 PF04056.14 CDO77639.1 - 1e-70 237.5 0.0 1.3e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 CDO77639.1 - 8.8e-13 48.8 0.0 1.6e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain ADH_N PF08240.12 CDO77640.1 - 2e-27 95.2 1.8 3.2e-27 94.6 1.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CDO77640.1 - 3e-16 59.6 0.0 5.5e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CDO77640.1 - 4.2e-07 29.5 0.0 7.6e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 CDO77640.1 - 4.6e-06 27.7 0.0 7.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CDO77640.1 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CDO77640.1 - 0.029 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DJ-1_PfpI PF01965.24 CDO77640.1 - 0.098 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family NAD_binding_2 PF03446.15 CDO77640.1 - 0.15 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Phage_integrase PF00589.22 CDO77642.1 - 0.0072 16.1 0.0 0.0095 15.7 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DDE_3 PF13358.6 CDO77644.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Trp_syntA PF00290.20 CDO77645.1 - 4.1e-86 288.0 0.4 5.8e-86 287.5 0.4 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 CDO77645.1 - 3.4e-48 164.5 0.6 5.5e-48 163.9 0.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 CDO77645.1 - 0.00031 20.3 0.1 0.0011 18.4 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 CDO77645.1 - 0.0015 18.0 0.1 0.0024 17.3 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase PA PF02225.22 CDO77645.1 - 0.042 13.9 0.5 8.2 6.5 0.0 2.9 3 0 0 3 3 3 0 PA domain Asparaginase PF00710.20 CDO77646.1 - 1.8e-55 187.5 0.0 2.1e-54 184.0 0.0 2.3 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CDO77646.1 - 9.9e-30 103.1 0.0 2.4e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 CDO77646.1 - 2e-05 25.1 0.0 4.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CDO77646.1 - 0.00064 20.1 0.2 0.0029 18.0 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CDO77646.1 - 0.0028 18.0 0.1 0.019 15.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CDO77646.1 - 0.0081 16.5 0.2 0.023 15.0 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CDO77646.1 - 0.026 15.1 0.0 0.082 13.5 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) GATase_7 PF13537.6 CDO77646.1 - 0.096 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain Fib_alpha PF08702.10 CDO77647.1 - 0.0087 16.3 9.9 0.0087 16.3 9.9 2.2 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 CDO77647.1 - 0.1 12.6 0.2 0.1 12.6 0.2 4.4 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1515 PF07439.11 CDO77647.1 - 0.27 11.3 2.6 0.82 9.7 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) GP24_25 PF17388.2 CDO77647.1 - 0.33 10.9 6.2 2.9 7.9 1.1 2.7 1 1 1 2 2 2 0 Tail assembly gene products 24 & 25 FapA PF03961.13 CDO77647.1 - 0.5 8.9 16.4 0.077 11.6 10.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A PXA PF02194.15 CDO77647.1 - 1.8 8.5 4.9 3.2 7.7 4.9 1.4 1 0 0 1 1 1 0 PXA domain APG6_N PF17675.1 CDO77647.1 - 2.1 8.9 26.3 3.6 8.1 6.2 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region CAML PF14963.6 CDO77647.1 - 2.1 8.4 9.4 3.3 7.8 8.8 1.5 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF3584 PF12128.8 CDO77647.1 - 4.3 4.7 22.1 6.3 4.2 22.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1043 PF06295.12 CDO77647.1 - 5.6 7.0 13.5 2.8 7.9 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) V_ATPase_I PF01496.19 CDO77647.1 - 5.7 4.7 11.0 7.8 4.3 11.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family A_deaminase PF00962.22 CDO77648.1 - 6.4e-23 81.6 0.0 8.4e-20 71.3 0.0 2.3 2 1 0 2 2 2 2 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 CDO77648.1 - 0.071 12.4 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Amidohydrolase family Myb_DNA-bind_4 PF13837.6 CDO77649.1 - 2e-09 37.7 0.1 3.9e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CDO77649.1 - 2.9e-09 37.8 0.1 4.6e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO77649.1 - 0.001 19.1 0.1 0.0039 17.2 0.1 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myc_N PF01056.18 CDO77649.1 - 0.0054 16.7 0.8 0.0093 15.9 0.8 1.4 1 0 0 1 1 1 1 Myc amino-terminal region Myb_DNA-binding PF00249.31 CDO77649.1 - 0.023 14.9 0.2 0.051 13.8 0.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain TAP42 PF04177.12 CDO77649.1 - 0.036 13.2 0.7 0.058 12.5 0.7 1.3 1 0 0 1 1 1 0 TAP42-like family TAL_effector PF03377.13 CDO77649.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 TAL effector repeat RRN3 PF05327.11 CDO77649.1 - 0.29 9.6 2.6 0.36 9.3 2.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CDO77649.1 - 1.5 6.8 4.9 2.2 6.3 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 CDO77649.1 - 4.7 7.7 10.6 10 6.6 10.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DDE_Tnp_4 PF13359.6 CDO77650.1 - 3.3e-15 56.1 0.0 5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO77650.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain HTH_38 PF13936.6 CDO77650.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Bac_DnaA_C PF08299.11 CDO77650.1 - 0.16 12.1 0.2 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein helix-turn-helix PYC_OADA PF02436.18 CDO77651.1 - 5.2e-72 241.8 0.0 7e-72 241.3 0.0 1.2 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 CDO77651.1 - 3.3e-21 76.1 0.3 5.1e-21 75.4 0.3 1.2 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CDO77651.1 - 1.1e-17 63.6 4.9 3.7e-17 61.9 4.9 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CDO77651.1 - 4.4e-12 45.6 3.0 3.4e-05 23.6 0.1 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 CDO77651.1 - 7.7e-06 25.3 0.7 0.0068 15.7 0.1 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CDO77651.1 - 1.5e-05 25.7 1.4 0.019 15.6 0.2 2.8 3 0 0 3 3 3 2 HlyD family secretion protein GCV_H PF01597.19 CDO77651.1 - 0.0022 17.8 1.7 0.006 16.5 0.6 2.1 1 1 1 2 2 2 1 Glycine cleavage H-protein DUF2118 PF09891.9 CDO77651.1 - 0.0061 16.5 0.6 0.62 10.0 0.5 3.0 2 1 1 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2118) NQRA PF05896.11 CDO77651.1 - 0.016 14.7 0.4 0.034 13.6 0.4 1.5 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 CDO77651.1 - 0.032 14.2 2.0 0.14 12.1 1.9 2.1 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Phage_tail_NK PF16532.5 CDO77651.1 - 0.069 12.8 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales PTS_EIIA_1 PF00358.20 CDO77651.1 - 0.1 12.3 0.9 3 7.6 0.4 3.2 3 1 1 4 4 4 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 CDO77651.1 - 0.11 12.7 0.7 0.72 10.1 0.7 2.4 1 1 0 1 1 1 0 Peptidase family M23 CPSase_L_D2 PF02786.17 CDO77652.1 - 1e-79 267.0 0.1 1.5e-79 266.4 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CDO77652.1 - 6.6e-41 139.3 0.0 1.3e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CDO77652.1 - 3e-31 107.7 0.0 6.6e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 CDO77652.1 - 1.8e-10 40.7 0.0 3.8e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CDO77652.1 - 1e-07 31.7 0.1 2.1e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CDO77652.1 - 7.6e-05 22.8 0.0 0.00014 22.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 CDO77652.1 - 0.00026 20.6 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HMGL-like PF00682.19 CDO77652.1 - 0.00077 19.1 0.0 0.0023 17.5 0.0 1.8 1 0 0 1 1 1 1 HMGL-like GARS_A PF01071.19 CDO77652.1 - 0.0016 18.2 0.0 0.0043 16.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 CDO77652.1 - 0.0092 15.3 0.0 0.022 14.0 0.0 1.6 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp UAA PF08449.11 CDO77653.1 - 4e-11 42.7 14.7 5e-11 42.4 14.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDO77653.1 - 1.7e-05 25.0 23.7 5.1e-05 23.5 8.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family FA_hydroxylase PF04116.13 CDO77654.1 - 6.7e-22 78.3 13.5 6.7e-22 78.3 13.5 2.8 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Ribosomal_L28e PF01778.17 CDO77655.1 - 4.1e-32 111.3 1.8 4.1e-32 111.3 1.8 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CDO77655.1 - 8.3e-29 100.1 15.5 8.3e-29 100.1 15.5 2.6 2 0 0 2 2 2 1 Mak16 protein C-terminal region TFIIF_alpha PF05793.12 CDO77655.1 - 0.1 11.2 25.0 0.14 10.7 25.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 CDO77655.1 - 0.14 11.5 30.2 0.19 11.0 30.2 1.3 1 1 0 1 1 1 0 BUD22 TFIIA PF03153.13 CDO77655.1 - 0.14 12.1 9.9 0.17 11.8 9.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 CDO77655.1 - 0.71 8.1 16.1 1 7.6 16.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 CDO77655.1 - 2 6.4 7.1 2.6 6.1 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 CDO77655.1 - 4.1 6.1 7.3 5.3 5.7 7.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1840 PF08895.11 CDO77655.1 - 4.5 7.7 7.0 1.6 9.1 1.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF1640 PF07798.11 CDO77656.1 - 5e-61 205.8 14.0 6e-61 205.5 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) KIAA1430 PF13879.6 CDO77656.1 - 0.047 14.5 8.9 0.079 13.7 8.9 1.4 1 0 0 1 1 1 0 KIAA1430 homologue DotU PF09850.9 CDO77656.1 - 0.07 12.8 5.4 1.1 8.9 0.1 3.0 2 1 1 3 3 3 0 Type VI secretion system protein DotU BshC PF10079.9 CDO77656.1 - 0.29 9.8 10.8 0.21 10.3 9.3 1.3 1 1 0 1 1 1 0 Bacillithiol biosynthesis BshC Uso1_p115_C PF04871.13 CDO77656.1 - 0.94 9.9 13.0 0.2 12.1 7.0 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region V_ATPase_I PF01496.19 CDO77656.1 - 1.5 6.7 8.3 1.7 6.5 8.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 CDO77656.1 - 1.7 9.1 9.3 0.12 12.8 1.6 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4130 PF13566.6 CDO77656.1 - 1.8 8.6 5.8 17 5.5 0.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4130 Fungal_TACC PF12709.7 CDO77656.1 - 2.1 8.8 10.2 2.8 8.4 4.8 2.9 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Guanylate_kin PF00625.21 CDO77657.1 - 2e-69 232.9 0.0 2.4e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 CDO77657.1 - 1.3e-09 38.7 0.1 5.4e-09 36.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CDO77657.1 - 6.2e-06 26.4 0.0 4e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDO77657.1 - 0.00012 22.4 0.0 0.00048 20.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CDO77657.1 - 0.0003 20.8 0.0 0.00064 19.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CDO77657.1 - 0.00031 21.3 0.1 0.0021 18.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CDO77657.1 - 0.00079 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 CDO77657.1 - 0.0012 19.3 0.0 0.0018 18.8 0.0 1.4 1 1 0 1 1 1 1 ABC transporter KAP_NTPase PF07693.14 CDO77657.1 - 0.0032 16.8 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.6 CDO77657.1 - 0.004 17.2 0.0 0.0062 16.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CDO77657.1 - 0.0059 16.5 0.1 0.025 14.5 0.1 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 CDO77657.1 - 0.0074 16.2 0.0 0.017 15.0 0.0 1.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 CDO77657.1 - 0.0076 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Rad17 PF03215.15 CDO77657.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.5 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_28 PF13521.6 CDO77657.1 - 0.015 15.6 0.1 0.04 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CDO77657.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain dNK PF01712.19 CDO77657.1 - 0.016 15.1 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_24 PF13479.6 CDO77657.1 - 0.02 14.6 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CDO77657.1 - 0.027 14.5 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CDO77657.1 - 0.031 14.7 0.1 0.11 12.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PTS_IIB PF02302.17 CDO77657.1 - 0.032 14.9 0.0 12 6.7 0.0 3.0 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit NTPase_1 PF03266.15 CDO77657.1 - 0.034 14.1 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 CDO77657.1 - 0.04 13.7 0.0 0.081 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CDO77657.1 - 0.079 12.2 0.0 0.75 9.0 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CDO77657.1 - 0.11 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 CDO77657.1 - 0.12 12.8 0.0 0.53 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CDO77657.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CDO77657.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 CDO77657.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Septin MobB PF03205.14 CDO77657.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 CDO77657.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 CDO77658.1 - 2.1e-64 217.5 0.0 3.3e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO77658.1 - 1.2e-35 123.0 0.0 1.7e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO77658.1 - 1.2e-08 34.6 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CDO77658.1 - 0.0002 20.3 0.0 0.00039 19.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO77658.1 - 0.0035 17.3 0.2 0.008 16.1 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CDO77658.1 - 0.004 16.5 0.1 0.004 16.5 0.1 2.7 4 0 0 4 4 4 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CDO77658.1 - 0.022 13.7 0.1 0.036 13.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CDO77658.1 - 0.035 13.7 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 RIO1 family UAA PF08449.11 CDO77659.1 - 2.2e-67 227.4 5.4 2.6e-67 227.2 5.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CDO77659.1 - 5.3e-07 29.9 21.1 0.0028 17.8 6.8 2.5 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CDO77659.1 - 0.0012 17.8 0.4 0.0019 17.2 0.4 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 CDO77659.1 - 0.0032 16.8 7.9 0.012 14.8 7.8 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 CDO77659.1 - 0.093 12.2 2.1 0.093 12.2 0.5 1.8 2 0 0 2 2 2 0 Solute carrier family 35 TPT PF03151.16 CDO77659.1 - 0.1 11.9 8.5 0.17 11.2 0.2 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF4131 PF13567.6 CDO77659.1 - 0.13 11.9 3.4 0.32 10.6 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) CTD_bind PF04818.13 CDO77660.1 - 0.12 13.2 0.1 1.3 9.9 0.0 3.0 2 0 0 2 2 2 0 RNA polymerase II-binding domain. ABC_membrane PF00664.23 CDO77661.1 - 1.2e-65 221.9 35.7 4e-34 118.5 5.8 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CDO77661.1 - 6.9e-53 178.8 0.0 4.1e-32 111.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CDO77661.1 - 3.9e-10 39.6 0.0 0.014 14.9 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CDO77661.1 - 9.7e-06 26.1 0.3 0.0019 18.6 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 CDO77661.1 - 2.8e-05 24.2 1.8 0.21 11.7 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 CDO77661.1 - 0.0002 21.3 3.4 4.3 7.1 0.1 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CDO77661.1 - 0.00078 19.1 0.9 0.18 11.6 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CDO77661.1 - 0.0052 16.7 0.4 1.5 8.7 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 CDO77661.1 - 0.0055 16.4 0.3 2.2 8.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 CDO77661.1 - 0.0077 16.3 6.4 0.068 13.3 0.1 2.9 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_23 PF13476.6 CDO77661.1 - 0.01 16.4 0.1 3.2 8.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CDO77661.1 - 0.019 13.9 0.0 5.9 5.8 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CDO77661.1 - 0.036 14.1 3.4 1.2 9.2 0.2 2.6 2 0 0 2 2 2 0 Dynamin family DUF4574 PF15141.6 CDO77661.1 - 0.046 13.6 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Roc PF08477.13 CDO77661.1 - 0.11 12.7 0.4 18 5.6 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 CDO77661.1 - 0.13 11.6 0.1 5.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 CDO77661.1 - 0.13 11.8 0.0 22 4.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CDO77661.1 - 0.16 11.6 2.4 2.6 7.6 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 CDO77661.1 - 0.32 10.4 1.0 0.51 9.8 0.1 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein MobB PF03205.14 CDO77661.1 - 0.38 10.7 1.5 6.3 6.7 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.9 CDO77661.1 - 0.38 9.5 2.4 0.23 10.2 0.0 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 CDO77661.1 - 0.49 10.3 2.0 24 4.8 0.2 2.8 3 0 0 3 3 2 0 NACHT domain NB-ARC PF00931.22 CDO77661.1 - 0.83 8.8 4.6 12 5.0 0.8 2.9 3 1 0 3 3 3 0 NB-ARC domain AAA_22 PF13401.6 CDO77661.1 - 2.8 8.2 5.3 14 6.0 0.1 3.7 4 1 0 4 4 2 0 AAA domain MS_channel PF00924.18 CDO77662.1 - 2.3e-18 66.5 1.3 4.2e-18 65.7 1.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 CDO77662.1 - 0.00012 21.4 0.1 0.0003 20.1 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CDO77662.1 - 0.00067 19.4 0.1 0.0017 18.2 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CDO77662.1 - 0.0025 17.2 0.1 0.0074 15.7 0.1 1.7 1 0 0 1 1 1 1 EF hand DUF2207 PF09972.9 CDO77662.1 - 0.027 13.3 0.3 3.3 6.4 0.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3098 PF11297.8 CDO77662.1 - 0.033 13.8 1.2 0.081 12.5 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) EF-hand_7 PF13499.6 CDO77662.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_C12 PF01088.21 CDO77663.1 - 4e-26 92.1 0.0 1.9e-19 70.3 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 zf-ZPR1 PF03367.13 CDO77664.1 - 4e-114 377.8 0.5 2.7e-58 196.4 0.1 3.1 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 CDO77664.1 - 0.071 13.1 3.7 1.2 9.1 0.5 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FpoO PF10621.9 CDO77664.1 - 0.33 11.3 1.8 1.1 9.6 0.4 2.4 2 0 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO zf-DNL PF05180.12 CDO77664.1 - 0.7 9.9 3.7 4.8 7.2 1.6 2.5 2 0 0 2 2 2 0 DNL zinc finger DZR PF12773.7 CDO77664.1 - 2.4 8.2 7.6 1.8 8.6 1.0 3.1 2 2 1 3 3 3 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CDO77664.1 - 3.9 7.7 7.9 7.1 6.8 0.1 3.2 3 1 0 3 3 3 0 Zinc ribbon domain Nup35_RRM PF05172.13 CDO77665.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Cyto_heme_lyase PF01265.17 CDO77667.1 - 1.7e-83 280.6 9.3 4.4e-82 276.0 9.3 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Tim44 PF04280.15 CDO77668.1 - 5e-37 127.3 1.6 6.5e-37 126.9 0.2 1.9 2 0 0 2 2 2 1 Tim44-like domain CENP-O PF09496.10 CDO77668.1 - 0.0072 16.3 6.3 0.32 10.9 1.2 2.4 2 1 0 2 2 2 2 Cenp-O kinetochore centromere component DMPK_coil PF08826.10 CDO77668.1 - 0.027 14.6 0.5 0.027 14.6 0.5 2.4 3 0 0 3 3 3 0 DMPK coiled coil domain like DHquinase_II PF01220.19 CDO77668.1 - 0.041 13.5 0.3 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Dehydroquinase class II IMS PF00817.20 CDO77668.1 - 0.093 12.7 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 impB/mucB/samB family DUF3813 PF12758.7 CDO77668.1 - 0.46 10.9 6.1 5 7.5 3.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) ADH_zinc_N PF00107.26 CDO77669.1 - 5.2e-15 55.6 0.0 7.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO77669.1 - 0.00072 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 CDO77669.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 CDO77669.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family EMP24_GP25L PF01105.24 CDO77670.1 - 8.2e-48 162.8 0.1 9.6e-48 162.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Brix PF04427.18 CDO77671.1 - 3.2e-23 82.8 0.5 6.2e-23 81.9 0.5 1.5 1 0 0 1 1 1 1 Brix domain Sec62 PF03839.16 CDO77671.1 - 1 8.8 8.9 0.58 9.6 1.1 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 Glyco_hydro_7 PF00840.20 CDO77672.1 - 1.7e-213 709.2 12.2 1.9e-213 709.0 12.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pkinase PF00069.25 CDO77673.1 - 7.6e-05 22.2 0.0 8.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 CDO77673.1 - 0.0013 18.2 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 CDO77673.1 - 0.0034 16.3 0.0 0.027 13.3 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1679) Kdo PF06293.14 CDO77673.1 - 0.0068 15.8 0.0 0.008 15.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO77675.1 - 1.9e-10 41.1 2.0 1.1e-09 38.5 2.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CDO77675.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 CDO77675.1 - 0.039 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CDO77675.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATG16 PF08614.11 CDO77676.1 - 0.0015 18.8 10.7 0.016 15.4 6.2 2.6 3 0 0 3 3 2 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CDO77676.1 - 0.005 15.8 5.8 0.091 11.6 1.6 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein GAS PF13851.6 CDO77676.1 - 0.014 14.8 7.5 0.1 11.9 1.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3987 PF13148.6 CDO77676.1 - 0.017 14.1 0.7 0.047 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MscS_porin PF12795.7 CDO77676.1 - 0.02 14.5 15.7 0.017 14.7 7.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain SKA1 PF07160.12 CDO77676.1 - 0.046 13.6 2.1 7.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 TRAF_BIRC3_bd PF16673.5 CDO77676.1 - 0.067 13.0 0.2 0.067 13.0 0.2 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain CENP-F_leu_zip PF10473.9 CDO77676.1 - 0.071 13.1 13.6 0.36 10.8 8.2 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.19 CDO77676.1 - 0.082 10.7 8.0 0.27 9.0 3.2 2.0 2 0 0 2 2 2 0 Myosin tail Rootletin PF15035.6 CDO77676.1 - 0.1 12.6 6.9 0.046 13.8 2.1 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Macoilin PF09726.9 CDO77676.1 - 0.1 11.1 3.8 0.053 12.1 0.8 1.8 2 0 0 2 2 2 0 Macoilin family YabA PF06156.13 CDO77676.1 - 0.12 13.1 2.0 26 5.5 0.0 2.4 2 0 0 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 CDO77676.1 - 0.12 12.2 7.3 0.049 13.5 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Tropomyosin PF00261.20 CDO77676.1 - 0.13 11.6 10.4 0.17 11.3 4.5 2.2 2 0 0 2 2 2 0 Tropomyosin USP8_interact PF08941.10 CDO77676.1 - 0.16 11.8 2.1 14 5.4 0.2 2.7 2 1 1 3 3 3 0 USP8 interacting Fez1 PF06818.15 CDO77676.1 - 0.18 12.3 4.2 5.8 7.3 3.1 2.1 2 0 0 2 2 2 0 Fez1 DASH_Hsk3 PF08227.11 CDO77676.1 - 0.24 11.8 4.3 8.2 6.9 0.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like CCDC144C PF14915.6 CDO77676.1 - 0.25 10.4 12.1 0.043 12.9 5.1 2.3 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region Cep57_CLD_2 PF14197.6 CDO77676.1 - 0.28 11.3 13.6 0.97 9.6 1.6 3.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Phage_GP20 PF06810.11 CDO77676.1 - 0.36 10.6 5.2 1.6 8.5 1.5 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 FH2 PF02181.23 CDO77676.1 - 0.38 9.8 4.3 1.7 7.6 0.1 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain NPV_P10 PF05531.12 CDO77676.1 - 0.48 10.9 6.2 1.1 9.8 0.5 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4600 PF15372.6 CDO77676.1 - 0.5 10.8 3.8 1.4 9.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF4472 PF14739.6 CDO77676.1 - 0.72 10.6 6.5 0.32 11.8 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF1664 PF07889.12 CDO77676.1 - 0.77 9.8 8.1 3 7.9 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 CDO77676.1 - 0.78 10.2 7.5 13 6.3 0.1 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMPIT PF07851.13 CDO77676.1 - 0.79 8.9 4.3 0.28 10.4 1.2 1.6 2 0 0 2 2 2 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 CDO77676.1 - 0.93 9.8 5.2 12 6.2 1.2 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Golgin_A5 PF09787.9 CDO77676.1 - 1.5 8.2 8.8 2.6 7.5 3.8 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 CDO77676.1 - 1.6 8.8 12.2 2.7 8.1 5.0 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lipoprotein_20 PF13942.6 CDO77676.1 - 1.7 8.5 7.7 4.7 7.1 0.1 2.3 2 0 0 2 2 2 0 YfhG lipoprotein Jnk-SapK_ap_N PF09744.9 CDO77676.1 - 1.9 8.7 10.8 6 7.1 4.8 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Csm1_N PF18504.1 CDO77676.1 - 2 8.8 9.1 9.1 6.7 0.7 2.6 2 1 0 2 2 2 0 Csm1 N-terminal domain DUF4200 PF13863.6 CDO77676.1 - 2.3 8.6 7.3 2 8.8 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DMPK_coil PF08826.10 CDO77676.1 - 3.4 7.8 10.2 0.41 10.8 4.0 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like PRKG1_interact PF15898.5 CDO77676.1 - 4.8 8.1 10.4 35 5.4 5.3 2.6 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 CDO77676.1 - 5.6 7.5 14.6 2.4 8.7 7.8 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region betaPIX_CC PF16523.5 CDO77676.1 - 5.8 6.8 7.9 9.5 6.1 0.4 2.6 2 1 1 3 3 3 0 betaPIX coiled coil CENP-H PF05837.12 CDO77676.1 - 7.5 7.0 13.0 5.8 7.4 5.1 2.7 2 1 0 2 2 2 0 Centromere protein H (CENP-H) SlyX PF04102.12 CDO77676.1 - 7.5 7.2 10.0 23 5.7 0.6 2.8 2 0 0 2 2 2 0 SlyX TMF_TATA_bd PF12325.8 CDO77676.1 - 7.8 6.8 13.9 12 6.1 0.3 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tropomyosin_1 PF12718.7 CDO77676.1 - 8.4 6.5 12.8 5.8 7.1 0.5 2.3 2 0 0 2 2 2 0 Tropomyosin like DUF1771 PF08590.10 CDO77677.1 - 9.2e-15 54.8 9.1 1.7e-14 53.9 9.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 CDO77677.1 - 5.5e-09 35.8 8.4 6.4e-07 29.2 1.3 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CDO77677.1 - 1e-08 34.9 7.4 3.8e-06 26.7 0.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CDO77677.1 - 2.2e-07 31.5 3.4 2.8e-06 28.0 0.1 2.4 1 1 1 2 2 2 1 Torus domain Smr PF01713.21 CDO77677.1 - 1.2e-06 28.8 0.0 3.4e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH_4 PF18044.1 CDO77677.1 - 0.00019 21.1 12.6 0.0096 15.7 1.1 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger zf-C3H1 PF10650.9 CDO77677.1 - 0.00031 20.4 3.6 0.033 13.9 0.4 2.4 2 0 0 2 2 2 2 Putative zinc-finger domain zf-CCCH_3 PF15663.5 CDO77677.1 - 0.00056 20.1 2.6 0.68 10.2 0.2 2.3 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 CDO77677.1 - 0.00064 20.1 5.3 0.12 12.9 0.9 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger UBA PF00627.31 CDO77677.1 - 0.012 15.5 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 UBA/TS-N domain HBS1_N PF08938.10 CDO77677.1 - 0.04 14.2 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus Fic PF02661.18 CDO77679.1 - 2.2e-05 25.3 0.2 6.5e-05 23.7 0.2 1.9 1 0 0 1 1 1 1 Fic/DOC family PAS_9 PF13426.7 CDO77680.1 - 0.13 12.5 0.0 7.1 6.9 0.0 2.4 2 1 1 3 3 3 0 PAS domain Coprogen_oxidas PF01218.18 CDO77681.1 - 5.2e-121 402.9 0.0 5.9e-121 402.7 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Lactamase_B PF00753.27 CDO77683.1 - 1.9e-08 34.6 5.3 3e-08 33.9 5.3 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Tcp11 PF05794.13 CDO77684.1 - 1.8e-15 57.0 0.0 6e-09 35.5 0.3 2.7 2 1 0 2 2 2 2 T-complex protein 11 MFS_1 PF07690.16 CDO77684.1 - 2.2e-06 26.8 23.2 2.8e-05 23.2 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Esterase_phd PF10503.9 CDO77685.1 - 7.9e-22 77.8 0.6 1.7e-21 76.7 0.6 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 CDO77685.1 - 2.6e-09 36.9 1.0 5.1e-09 35.9 1.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 CDO77685.1 - 0.023 13.6 0.2 0.023 13.6 0.2 1.8 2 0 0 2 2 2 0 Carboxylesterase family Mg_trans_NIPA PF05653.14 CDO77686.1 - 4.9e-15 55.4 7.4 2.2e-10 40.1 3.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 CDO77686.1 - 0.012 15.8 16.7 0.15 12.2 0.3 3.3 3 0 0 3 3 3 0 EamA-like transporter family DUF262 PF03235.14 CDO77687.1 - 6.3e-14 52.7 2.0 6.1e-13 49.5 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function DUF262 Med13_C PF06333.12 CDO77687.1 - 0.095 12.0 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Dcc1 PF09724.9 CDO77688.1 - 2.8e-82 276.7 0.0 3.3e-82 276.5 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 SBE2 PF17076.5 CDO77689.1 - 0.37 9.0 8.8 0.38 8.9 8.8 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation Macoilin PF09726.9 CDO77689.1 - 8.9 4.7 13.9 10 4.5 13.9 1.2 1 0 0 1 1 1 0 Macoilin family p450 PF00067.22 CDO77690.1 - 2.2e-62 211.3 1.4 2.4e-52 178.2 0.1 2.2 2 0 0 2 2 2 2 Cytochrome P450 Cation_efflux PF01545.21 CDO77691.1 - 1.2e-47 162.2 0.2 3.7e-47 160.7 0.2 1.7 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CDO77691.1 - 1.9e-06 27.9 0.3 4.4e-06 26.7 0.1 1.7 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter Peroxidase_ext PF11895.8 CDO77692.1 - 1.3e-27 95.6 0.6 2.3e-27 94.7 0.6 1.5 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 CDO77692.1 - 3.5e-23 82.5 0.0 5.4e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Caleosin PF05042.13 CDO77693.1 - 1.1e-80 269.5 0.0 1.4e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 CDO77693.1 - 0.96 9.5 3.1 12 6.1 0.1 2.8 3 0 0 3 3 3 0 EF-hand domain KRE1 PF17056.5 CDO77694.1 - 0.031 14.0 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 MFS_1 PF07690.16 CDO77695.1 - 1.4e-19 70.3 47.5 5.5e-14 51.9 30.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Asparaginase_2 PF01112.18 CDO77696.1 - 1.9e-67 227.5 0.1 1.6e-55 188.3 0.0 2.3 2 0 0 2 2 2 2 Asparaginase G_glu_transpept PF01019.21 CDO77696.1 - 0.1 11.4 0.2 0.19 10.5 0.1 1.5 2 0 0 2 2 2 0 Gamma-glutamyltranspeptidase Plavaka PF18759.1 CDO77698.1 - 7.9e-27 94.3 0.0 1.4e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Dynamitin PF04912.14 CDO77699.1 - 1.1e-51 176.3 20.1 8.5e-48 163.6 11.3 2.6 1 1 1 2 2 2 2 Dynamitin PhaP_Bmeg PF09602.10 CDO77699.1 - 4e-05 23.6 1.4 5.6e-05 23.1 0.4 1.8 2 0 0 2 2 2 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) SlyX PF04102.12 CDO77699.1 - 0.00042 20.9 5.3 1.1 9.9 1.6 4.0 3 1 0 3 3 3 1 SlyX JAKMIP_CC3 PF16034.5 CDO77699.1 - 0.0028 17.6 1.4 0.0028 17.6 1.4 1.9 2 0 0 2 2 2 1 JAKMIP CC3 domain TPR_MLP1_2 PF07926.12 CDO77699.1 - 0.0043 17.1 2.8 0.0043 17.1 2.8 3.1 4 0 0 4 4 3 1 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 CDO77699.1 - 0.044 14.1 2.5 0.8 10.0 0.3 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 CDO77699.1 - 0.053 13.5 1.7 0.36 10.9 0.1 2.9 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CDO77699.1 - 0.056 13.6 0.4 1 9.6 0.1 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 CDO77699.1 - 0.059 13.9 0.7 0.44 11.1 0.2 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.20 CDO77699.1 - 0.068 13.1 4.7 1.6 8.7 0.1 3.3 2 1 1 3 3 3 0 Prefoldin subunit Laminin_II PF06009.12 CDO77699.1 - 0.11 12.6 4.7 0.16 12.0 0.9 3.0 2 2 0 3 3 3 0 Laminin Domain II HSBP1 PF06825.12 CDO77699.1 - 0.11 12.3 4.9 5.5 6.9 0.6 3.6 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Apc15p PF05841.11 CDO77699.1 - 0.13 13.1 1.9 0.43 11.4 1.9 1.9 1 1 0 1 1 1 0 Apc15p protein WXG100 PF06013.12 CDO77699.1 - 0.14 12.4 1.1 0.77 10.0 0.5 2.6 3 0 0 3 3 2 0 Proteins of 100 residues with WXG Rootletin PF15035.6 CDO77699.1 - 0.29 11.1 4.9 0.85 9.6 4.9 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Hemagglutinin PF00509.18 CDO77699.1 - 0.39 9.0 0.5 0.71 8.2 0.3 1.4 2 0 0 2 2 2 0 Haemagglutinin Phasin PF05597.11 CDO77699.1 - 1.2 9.2 7.3 12 5.9 0.1 3.4 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Lebercilin PF15619.6 CDO77699.1 - 1.7 8.3 14.7 0.24 11.0 3.9 2.9 4 0 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease MIP-T3_C PF17749.1 CDO77699.1 - 2.3 8.2 7.4 3.8 7.5 1.0 3.8 3 2 0 4 4 4 0 Microtubule-binding protein MIP-T3 C-terminal region AAA_13 PF13166.6 CDO77699.1 - 2.3 6.7 6.5 1.3 7.5 0.4 2.6 3 0 0 3 3 3 0 AAA domain CENP-H PF05837.12 CDO77699.1 - 6.5 7.2 8.8 0.31 11.5 0.7 2.7 3 0 0 3 3 2 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 CDO77699.1 - 7.1 7.1 8.0 1e+02 3.4 0.0 4.1 4 1 0 4 4 3 0 Flagella accessory protein C (FlaC) Helo_like_N PF17111.5 CDO77699.1 - 9.1 5.6 6.4 13 5.1 0.1 3.1 3 1 1 4 4 4 0 Fungal N-terminal domain of STAND proteins Hydrolase_like PF13242.6 CDO77700.1 - 3.7e-26 91.0 0.0 7.4e-26 90.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 CDO77700.1 - 0.00034 20.7 0.0 0.00068 19.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Pex24p PF06398.11 CDO77701.1 - 9.8e-22 77.4 4.8 1.4e-20 73.7 0.1 2.3 1 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Ank_2 PF12796.7 CDO77702.1 - 4.1e-17 62.6 0.0 4.4e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CDO77702.1 - 3.8e-15 56.0 0.1 4.4e-05 24.0 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CDO77702.1 - 2.5e-14 53.0 2.7 3.8e-06 27.1 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CDO77702.1 - 2.5e-13 48.9 0.1 0.00083 19.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CDO77702.1 - 1e-11 44.8 0.3 0.00054 20.2 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Tho2 PF11262.8 CDO77705.1 - 0.0027 17.0 5.8 0.0053 16.0 5.8 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 ApoO PF09769.9 CDO77705.1 - 0.0084 16.1 0.6 0.024 14.6 0.6 1.8 1 1 0 1 1 1 1 Apolipoprotein O DUF4062 PF13271.6 CDO77705.1 - 0.02 15.3 0.7 24 5.4 0.3 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4062) DUF3106 PF11304.8 CDO77705.1 - 0.026 15.0 4.2 0.073 13.5 4.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) PilZ PF07238.14 CDO77705.1 - 0.031 14.6 0.1 6.2 7.2 0.1 3.0 1 1 1 2 2 2 0 PilZ domain STAT_alpha PF01017.20 CDO77705.1 - 0.033 14.1 10.2 0.1 12.5 6.4 2.7 2 1 0 2 2 2 0 STAT protein, all-alpha domain ApoLp-III PF07464.11 CDO77705.1 - 0.062 13.4 7.3 0.027 14.5 3.3 2.4 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) 4HB_MCP_1 PF12729.7 CDO77705.1 - 0.11 12.0 6.4 0.29 10.7 6.4 1.7 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Nup188 PF10487.9 CDO77705.1 - 0.19 9.6 2.3 0.35 8.7 2.3 1.3 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 DUF5344 PF17279.2 CDO77705.1 - 0.35 11.5 5.2 1.4 9.5 2.5 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5344) DUF4407 PF14362.6 CDO77705.1 - 0.66 9.3 10.2 1.1 8.5 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bacillus_HBL PF05791.11 CDO77705.1 - 0.85 9.4 11.6 4.8 7.0 3.0 2.9 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) YtxH PF12732.7 CDO77705.1 - 1 9.9 7.8 9.8 6.8 7.0 2.8 2 1 0 2 2 1 0 YtxH-like protein DUF1640 PF07798.11 CDO77705.1 - 1 9.4 15.1 2 8.4 15.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF948 PF06103.11 CDO77705.1 - 1.1 9.5 3.3 3.4 8.0 0.6 3.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 CDO77705.1 - 2 8.8 16.3 6.7 7.1 16.3 1.9 1 1 0 1 1 1 0 Fez1 Gp-FAR-1 PF05823.12 CDO77705.1 - 4.2 7.7 9.3 1.5 9.2 5.3 2.2 2 2 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Peptidase_S49_N PF08496.10 CDO77705.1 - 6.5 6.8 7.8 13 5.8 7.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LCD1 PF09798.9 CDO77705.1 - 10 4.5 13.5 17 3.8 13.5 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein ADH_zinc_N PF00107.26 CDO77707.1 - 1.1e-21 77.2 0.0 2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CDO77707.1 - 2e-14 54.8 0.0 3.6e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CDO77707.1 - 2.2e-05 24.3 0.0 7.8e-05 22.5 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain APG5 PF04106.12 CDO77708.1 - 9.5e-63 211.8 0.0 1.2e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF913 PF06025.12 CDO77710.1 - 4.6e-102 341.8 0.0 4.6e-102 341.8 0.0 5.5 5 0 0 5 5 5 2 Domain of Unknown Function (DUF913) HECT PF00632.25 CDO77710.1 - 3.1e-97 325.8 0.0 5e-97 325.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 CDO77710.1 - 1e-90 304.8 1.0 1e-90 304.8 1.0 3.5 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) UBM PF14377.6 CDO77710.1 - 1.8e-26 90.7 18.6 1.7e-11 43.2 0.8 3.9 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 CDO77710.1 - 8.7e-11 41.5 0.1 2.2e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF3361 PF11841.8 CDO77710.1 - 0.0026 17.7 3.5 5.2 7.0 0.0 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF3361) PC4 PF02229.16 CDO77711.1 - 3.8e-24 84.1 0.4 5.7e-24 83.5 0.4 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) ABC1 PF03109.16 CDO77712.1 - 2.9e-33 114.6 0.0 5e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CDO77712.1 - 9.4e-06 25.3 0.2 6.6e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 CDO77712.1 - 0.03 13.7 0.0 0.09 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain RabGAP-TBC PF00566.18 CDO77713.1 - 1.7e-53 181.5 0.3 3.3e-53 180.5 0.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CENP-F_leu_zip PF10473.9 CDO77713.1 - 0.00024 21.1 7.4 0.00044 20.3 7.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 CDO77713.1 - 0.0003 20.8 9.6 0.00055 20.0 9.6 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 CCDC144C PF14915.6 CDO77713.1 - 0.0057 15.8 4.7 0.0084 15.3 4.7 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region APG6_N PF17675.1 CDO77713.1 - 0.0097 16.4 6.8 0.021 15.4 6.8 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region Pox_MCEL PF03291.16 CDO77713.1 - 0.024 13.7 0.6 0.037 13.1 0.6 1.2 1 0 0 1 1 1 0 mRNA capping enzyme HALZ PF02183.18 CDO77713.1 - 0.027 14.7 1.0 0.075 13.3 1.0 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper CtIP_N PF10482.9 CDO77713.1 - 0.043 13.9 2.7 0.099 12.7 2.7 1.5 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Cnn_1N PF07989.11 CDO77713.1 - 0.19 11.9 5.3 0.5 10.6 5.3 1.8 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Fez1 PF06818.15 CDO77713.1 - 0.27 11.6 4.8 0.59 10.6 4.8 1.5 1 0 0 1 1 1 0 Fez1 ZapB PF06005.12 CDO77713.1 - 0.36 11.3 5.9 0.91 10.0 5.9 1.7 1 1 0 1 1 1 0 Cell division protein ZapB DivIVA PF05103.13 CDO77713.1 - 0.39 10.8 6.3 0.71 10.0 5.5 1.9 1 1 1 2 2 2 0 DivIVA protein TAF PF02969.17 CDO77713.1 - 0.83 9.9 3.6 14 5.9 0.2 2.9 3 0 0 3 3 3 0 TATA box binding protein associated factor (TAF) FlaC_arch PF05377.11 CDO77713.1 - 0.85 10.1 3.2 1.6 9.2 0.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 CDO77713.1 - 2.3 8.7 8.0 4.4 7.8 8.0 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) AATF-Che1 PF13339.6 CDO77713.1 - 2.5 8.8 6.5 0.57 10.9 2.4 2.1 2 0 0 2 2 1 0 Apoptosis antagonizing transcription factor bZIP_1 PF00170.21 CDO77713.1 - 5.6 7.1 8.0 0.32 11.1 1.5 2.2 3 0 0 3 3 3 0 bZIP transcription factor DnaJ PF00226.31 CDO77714.1 - 0.00047 20.2 0.0 0.00087 19.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1180 PF06679.12 CDO77717.1 - 4.3 7.7 7.4 9.8 6.6 7.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Zn_clus PF00172.18 CDO77719.1 - 0.003 17.7 6.3 0.0058 16.7 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 CDO77719.1 - 1.4 9.0 11.0 7 6.9 11.0 2.3 1 0 0 1 1 1 0 AT hook motif Glyco_hydro_92 PF07971.12 CDO77720.1 - 4.9e-121 404.9 0.0 6.7e-121 404.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 CDO77720.1 - 2e-34 119.6 0.0 3.2e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain MFS_1 PF07690.16 CDO77721.1 - 9.3e-31 107.0 31.6 5.1e-30 104.6 32.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily AAA PF00004.29 CDO77722.1 - 5.5e-12 46.2 0.0 1e-11 45.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDO77722.1 - 0.0076 16.5 1.2 0.26 11.6 0.0 3.1 1 1 2 3 3 3 1 AAA domain MeaB PF03308.16 CDO77722.1 - 0.013 14.5 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 CDO77722.1 - 0.03 14.3 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CDO77722.1 - 0.038 13.7 0.1 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CDO77722.1 - 0.057 13.8 0.1 0.32 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Cren7 PF11520.8 CDO77722.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin protein Cren7 Glyco_hydro_92 PF07971.12 CDO77723.1 - 3.5e-91 306.5 2.0 4.9e-45 154.3 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 CDO77723.1 - 3.8e-36 125.2 0.1 1.2e-35 123.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain MFS_1 PF07690.16 CDO77724.1 - 4.2e-05 22.6 23.8 0.00028 19.9 23.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily PH PF00169.29 CDO77725.1 - 0.12 12.8 0.1 0.26 11.8 0.1 1.5 1 0 0 1 1 1 0 PH domain DIOX_N PF14226.6 CDO77726.1 - 1.5e-13 51.5 0.0 2.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CDO77726.1 - 1.4e-10 41.5 0.0 3.1e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L28 PF00830.19 CDO77727.1 - 2.8e-22 78.7 0.8 3.9e-22 78.2 0.8 1.2 1 0 0 1 1 1 1 Ribosomal L28 family Iso_dh PF00180.20 CDO77728.1 - 2.2e-73 247.4 0.0 2.6e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans PF04082.18 CDO77729.1 - 2.7e-19 69.2 0.4 5.5e-19 68.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CDO77729.1 - 0.00021 21.3 14.0 0.00041 20.4 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GWT1 PF06423.12 CDO77730.1 - 1.8e-39 135.3 0.0 3.4e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 GWT1 UNC-50 PF05216.13 CDO77730.1 - 5.3 6.5 14.1 1.6 8.2 0.2 3.5 3 0 0 3 3 3 0 UNC-50 family AA_permease_2 PF13520.6 CDO77731.1 - 2.1e-43 148.8 53.8 2.6e-43 148.4 53.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDO77731.1 - 3.9e-17 62.0 43.7 6.1e-17 61.4 43.5 1.3 1 1 0 1 1 1 1 Amino acid permease Thaumatin PF00314.17 CDO77734.1 - 7.7e-56 189.1 6.5 8e-55 185.8 6.5 2.0 1 1 0 1 1 1 1 Thaumatin family Glucan_synthase PF02364.15 CDO77735.1 - 0 1321.7 0.0 0 1321.2 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CDO77735.1 - 1.2e-41 142.1 0.3 3.6e-41 140.5 0.3 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Mitoc_mL59 PF18126.1 CDO77735.1 - 0.13 12.5 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Pkinase PF00069.25 CDO77736.1 - 3.6e-06 26.5 0.0 6.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDO77736.1 - 4.2e-06 26.3 0.0 6.5e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CDO77736.1 - 0.0072 16.3 0.0 0.023 14.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family HCV_core PF01542.18 CDO77736.1 - 0.027 14.8 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus core protein Glyco_hydro_8 PF01270.17 CDO77736.1 - 0.18 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 Exo_endo_phos_2 PF14529.6 CDO77737.1 - 4.5e-06 26.5 0.2 8.9e-06 25.5 0.2 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDO77737.1 - 0.0024 17.4 1.0 0.0054 16.3 1.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thiamine_BP PF01910.17 CDO77737.1 - 0.032 14.1 0.1 0.081 12.9 0.1 1.6 1 0 0 1 1 1 0 Thiamine-binding protein Prenyltrans PF00432.21 CDO77737.1 - 0.041 13.6 1.3 0.11 12.3 1.3 1.8 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat zf-CCHC PF00098.23 CDO77737.1 - 0.36 11.0 4.7 2.3 8.4 1.9 2.7 2 0 0 2 2 2 0 Zinc knuckle MscS_porin PF12795.7 CDO77737.1 - 0.53 9.8 3.1 0.97 8.9 3.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF1180 PF06679.12 CDO77739.1 - 0.018 15.5 0.4 0.047 14.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 CDO77739.1 - 0.024 14.6 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4446 PF14584.6 CDO77739.1 - 0.043 13.8 0.2 0.097 12.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Pkinase PF00069.25 CDO77740.1 - 1.3e-60 205.0 0.1 6.6e-50 169.9 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO77740.1 - 1.5e-24 86.7 0.2 6.8e-23 81.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO77740.1 - 0.00013 20.9 0.2 0.00027 19.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CDO77740.1 - 0.00016 21.7 0.1 0.042 13.8 0.0 2.7 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 CDO77740.1 - 0.00021 20.7 0.0 0.00051 19.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CDO77740.1 - 0.043 13.1 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Peroxidase_ext PF11895.8 CDO77741.1 - 5.1e-26 90.4 1.1 1.1e-25 89.3 1.1 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 CDO77741.1 - 1.8e-23 83.5 0.0 2.8e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase AAA PF00004.29 CDO77742.1 - 1.1e-14 55.0 0.0 4.6e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CDO77742.1 - 0.011 16.0 0.3 0.15 12.3 0.0 2.6 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CDO77742.1 - 0.087 13.2 0.1 0.25 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Yae1_N PF09811.9 CDO77743.1 - 0.0031 17.2 2.5 0.005 16.5 2.5 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Effector_1 PF04518.12 CDO77743.1 - 1.3 8.0 2.4 1.9 7.5 2.4 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Exo_endo_phos PF03372.23 CDO77744.1 - 3.4e-07 30.0 2.4 5.8e-07 29.3 2.4 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TB2_DP1_HVA22 PF03134.19 CDO77745.1 - 3.4e-27 94.2 3.1 5.5e-27 93.5 3.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ferritin_2 PF13668.6 CDO77746.1 - 8e-43 145.9 0.0 1.1e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain BRO1 PF03097.18 CDO77747.1 - 9e-122 406.6 1.4 1.5e-121 405.9 1.4 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CDO77747.1 - 2.8e-58 197.5 7.0 4.6e-58 196.8 7.0 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV ABC_trans_aux PF03886.13 CDO77747.1 - 0.006 16.2 0.3 0.014 15.0 0.3 1.6 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component eIF-5_eIF-2B PF01873.17 CDO77748.1 - 7.1e-43 145.2 0.1 1.1e-42 144.6 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 CDO77748.1 - 0.0016 17.9 0.3 0.0035 16.8 0.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-HYPF PF07503.12 CDO77748.1 - 0.091 12.6 0.2 18 5.2 0.0 2.8 2 0 0 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 CDO77748.1 - 0.64 10.4 4.3 9 6.7 0.0 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain RR_TM4-6 PF06459.12 CDO77748.1 - 2.6 7.8 10.3 3.8 7.3 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP-synt PF00231.19 CDO77749.1 - 7.5e-73 245.7 8.5 7.9e-72 242.3 8.5 1.9 1 1 0 1 1 1 1 ATP synthase NAD_Gly3P_dh_C PF07479.14 CDO77749.1 - 0.04 14.2 0.9 0.076 13.3 0.0 1.9 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Catalase PF00199.19 CDO77750.1 - 1.5e-168 560.9 0.5 4.5e-102 342.0 0.0 2.0 2 0 0 2 2 2 2 Catalase Catalase-rel PF06628.12 CDO77750.1 - 4e-15 55.8 0.0 1.1e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Ribonucleas_3_3 PF14622.6 CDO77751.1 - 2.3e-12 47.2 0.0 9.1e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CDO77751.1 - 0.0057 17.3 0.0 0.0076 16.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease III domain Fe_hyd_SSU PF02256.17 CDO77751.1 - 0.58 10.3 2.8 9.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Iron hydrogenase small subunit Peptidase_S9 PF00326.21 CDO77752.1 - 2e-45 154.9 0.0 3.2e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 CDO77752.1 - 7.1e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 CDO77752.1 - 2.3e-05 24.1 0.1 0.18 11.4 0.0 3.3 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 CDO77752.1 - 5.5e-05 22.9 0.1 0.28 10.8 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 CDO77752.1 - 0.0017 18.4 0.0 0.0054 16.8 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_3 PF07859.13 CDO77752.1 - 0.002 18.1 0.0 0.081 12.8 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CDO77752.1 - 0.0024 17.2 0.0 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 CDO77752.1 - 0.0071 15.9 0.0 0.018 14.5 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 CDO77752.1 - 0.048 13.3 0.1 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative esterase FSH1 PF03959.13 CDO77752.1 - 0.049 13.3 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PD40 PF07676.12 CDO77752.1 - 0.19 11.7 2.7 6.5 6.8 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PHD PF00628.29 CDO77753.1 - 0.0035 17.2 0.9 0.077 12.9 0.3 2.3 2 0 0 2 2 2 1 PHD-finger HscB_4_cys PF18256.1 CDO77753.1 - 2.2 8.2 6.4 3.7 7.4 0.1 2.9 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif Nup54 PF13874.6 CDO77754.1 - 7.7e-43 146.0 5.0 1.4e-42 145.1 4.1 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 CDO77754.1 - 9.9e-43 144.9 287.6 3.1e-14 53.6 39.1 5.8 1 1 6 7 7 7 7 Nucleoporin FG repeat region Nup54_C PF18437.1 CDO77754.1 - 0.00013 21.8 0.8 0.00013 21.8 0.8 2.4 3 0 0 3 3 3 1 Nup54 C-terminal interacting domain ZapA PF05164.13 CDO77754.1 - 0.13 12.7 3.9 12 6.4 1.5 2.6 2 0 0 2 2 2 0 Cell division protein ZapA Uso1_p115_C PF04871.13 CDO77754.1 - 1.7 9.1 7.0 6.7 7.1 7.0 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Pkinase PF00069.25 CDO77756.1 - 2.3e-13 50.1 0.2 2.5e-09 36.9 0.0 3.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO77756.1 - 2e-05 24.0 0.1 9.9e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CDO77756.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CDO77758.1 - 1.6e-09 37.6 0.0 7.9e-08 32.0 0.0 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO77758.1 - 0.02 14.2 0.6 0.17 11.1 0.1 2.4 2 1 1 3 3 3 0 Protein tyrosine kinase ACP_PD PF04336.12 CDO77758.1 - 0.039 14.4 0.7 0.092 13.2 0.3 1.7 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase Pkinase PF00069.25 CDO77759.1 - 1.5e-10 40.9 0.0 4.9e-08 32.6 0.0 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CDO77759.1 - 0.0018 17.6 0.1 0.01 15.2 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 CDO77760.1 - 2.1e-15 56.8 1.2 1.5e-05 25.7 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CDO77760.1 - 5.9e-05 23.3 0.0 0.77 10.1 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CDO77760.1 - 0.079 12.9 0.2 9.7 6.3 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Ferritin_2 PF13668.6 CDO77761.1 - 1.5e-29 102.9 0.0 2.2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.6 CDO77762.1 - 2.1e-29 102.5 0.1 2.8e-29 102.0 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ribosomal_L27e PF01777.18 CDO77763.1 - 1.1e-36 125.1 2.4 1.5e-36 124.6 2.4 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CDO77763.1 - 0.012 15.6 0.4 0.012 15.6 0.4 2.1 2 0 0 2 2 2 0 KOW motif U79_P34 PF03064.16 CDO77764.1 - 0.056 12.8 9.7 0.075 12.4 9.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Zn_clus PF00172.18 CDO77764.1 - 0.074 13.2 9.9 0.13 12.4 9.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4746 PF15928.5 CDO77764.1 - 0.14 11.5 3.7 0.17 11.3 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Vfa1 PF08432.10 CDO77764.1 - 1.9 8.8 11.6 2.5 8.4 11.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 CDO77764.1 - 5.9 5.5 4.3 6 5.5 4.3 1.0 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 CDO77764.1 - 6 6.9 8.6 7.7 6.6 8.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4407 PF14362.6 CDO77764.1 - 6.9 5.9 10.3 8.8 5.6 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_E PF05680.12 CDO77764.1 - 7.8 6.9 10.9 12 6.3 10.9 1.2 1 0 0 1 1 1 0 ATP synthase E chain DUF1840 PF08895.11 CDO77764.1 - 8.4 6.8 8.3 14 6.1 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Retrotrans_gag PF03732.17 CDO77765.1 - 4.9e-10 39.6 0.1 1.5e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO77765.1 - 1.7e-08 34.3 0.0 3.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) ATP-synt_G PF04718.15 CDO77766.1 - 3.9e-17 62.9 0.1 4e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Retrotrans_gag PF03732.17 CDO77769.1 - 0.00069 19.8 0.5 0.00069 19.8 0.5 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.27 CDO77770.1 - 1.8e-21 76.7 0.0 2.7e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO77770.1 - 1.2e-07 32.1 0.0 2.7e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO77770.1 - 8.9e-05 23.1 0.0 0.0002 22.0 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Arrestin_N PF00339.29 CDO77771.1 - 9.2e-09 35.5 0.0 1.4e-08 34.9 0.0 1.4 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CDO77771.1 - 0.041 13.6 0.0 0.054 13.2 0.0 1.1 1 0 0 1 1 1 0 Arrestin_N terminal like Arrestin_C PF02752.22 CDO77772.1 - 5.8e-10 39.7 0.1 1.4e-09 38.5 0.1 1.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Plavaka PF18759.1 CDO77773.1 - 1.8e-113 379.1 0.1 2.4e-113 378.6 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-MYND PF01753.18 CDO77774.1 - 0.093 12.8 2.7 0.24 11.5 2.7 1.6 1 0 0 1 1 1 0 MYND finger Glyco_hydro_3_C PF01915.22 CDO77775.1 - 2e-60 204.2 0.0 2.9e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CDO77775.1 - 1.3e-41 143.0 0.0 4.9e-41 141.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CDO77775.1 - 2.9e-22 78.6 0.7 5.6e-22 77.6 0.7 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 CDO77775.1 - 3.3e-16 59.4 0.0 6.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Aldo_ket_red PF00248.21 CDO77776.1 - 4.1e-72 242.9 0.0 5.4e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CDO77777.1 - 6.2e-72 242.3 0.0 7.7e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CDO77778.1 - 1.1e-70 238.1 0.0 1.4e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family 2OG-FeII_Oxy_3 PF13640.6 CDO77779.1 - 0.00031 21.6 0.0 0.00098 20.0 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CDO77780.1 - 0.00014 22.7 0.0 0.00024 21.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_9 PF08021.11 CDO77781.1 - 0.0011 19.2 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain LRR_6 PF13516.6 CDO77781.1 - 0.0018 18.2 10.5 31 5.0 0.0 7.7 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.7 CDO77781.1 - 0.03 14.7 11.3 26 5.4 0.1 6.0 3 3 4 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CDO77781.1 - 2.4 9.0 7.7 2.2e+02 3.0 0.0 6.1 7 0 0 7 7 7 0 Leucine Rich Repeat Myc_N PF01056.18 CDO77782.1 - 0.0027 17.7 1.2 0.0038 17.2 1.2 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Tub_N PF16322.5 CDO77782.1 - 0.003 18.0 1.3 0.0047 17.4 1.3 1.3 1 0 0 1 1 1 1 Tubby N-terminal Myb_DNA-bind_3 PF12776.7 CDO77782.1 - 0.025 15.6 0.0 0.044 14.8 0.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain TAP42 PF04177.12 CDO77782.1 - 0.029 13.5 0.9 0.043 13.0 0.9 1.3 1 0 0 1 1 1 0 TAP42-like family TAL_effector PF03377.13 CDO77782.1 - 0.054 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 TAL effector repeat RRN3 PF05327.11 CDO77782.1 - 0.12 10.9 3.0 0.14 10.7 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CDO77782.1 - 0.49 8.4 5.1 0.67 8.0 5.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 CDO77782.1 - 1 9.8 4.8 3 8.3 3.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 CDO77782.1 - 1.6 9.1 11.8 3.7 8.0 11.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LAT PF15234.6 CDO77782.1 - 3.7 7.2 9.7 2.4 7.8 7.8 1.6 1 1 0 1 1 1 0 Linker for activation of T-cells NOA36 PF06524.12 CDO77782.1 - 6.7 5.9 8.5 9.9 5.4 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein OrsD PF12013.8 CDO77783.1 - 0.017 15.5 8.9 0.043 14.2 8.9 1.7 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Actin_micro PF17003.5 CDO77783.1 - 0.042 13.0 0.0 1.5 7.9 0.0 2.1 1 1 0 1 1 1 0 Putative actin-like family zf-C3HC4_2 PF13923.6 CDO77783.1 - 0.17 11.8 5.4 0.14 12.0 3.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_2 PF12756.7 CDO77783.1 - 0.67 10.3 6.9 4.3 7.7 1.9 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) c-SKI_SMAD_bind PF08782.10 CDO77783.1 - 5.5 7.3 8.4 1.7 8.9 0.9 2.6 2 0 0 2 2 2 0 c-SKI Smad4 binding domain ARS2 PF04959.13 CDO77783.1 - 7.1 7.0 5.0 4.5 7.6 0.1 2.1 2 0 0 2 2 2 0 Arsenite-resistance protein 2 rve PF00665.26 CDO77784.1 - 2.5e-15 56.7 0.0 4.5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO77784.1 - 2.7e-07 30.4 0.1 5.2e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 CDO77784.1 - 0.14 11.9 0.4 0.61 9.9 0.0 2.2 3 0 0 3 3 3 0 Integrase core domain RP-C_C PF11800.8 CDO77785.1 - 0.24 11.5 16.9 1.5 8.8 3.5 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region CENP-Q PF13094.6 CDO77785.1 - 3 8.0 28.7 0.3 11.3 9.8 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.9 CDO77785.1 - 7.6 5.5 10.9 6.6 5.7 0.1 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 O-FucT PF10250.9 CDO77786.1 - 4.9e-05 23.2 0.0 7.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RVT_1 PF00078.27 CDO77787.1 - 2.1e-11 43.8 0.3 4.7e-11 42.6 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_2 PF13639.6 CDO77790.1 - 1.9e-05 24.9 1.0 3.4e-05 24.1 1.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CDO77790.1 - 2.7e-05 24.0 1.5 4.2e-05 23.3 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CDO77790.1 - 0.00016 21.4 0.6 0.00026 20.8 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDO77790.1 - 0.00023 21.3 0.4 0.00034 20.7 0.4 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CDO77790.1 - 0.00046 19.9 0.3 0.002 17.9 0.1 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CDO77790.1 - 0.00054 19.9 0.2 0.00086 19.3 0.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CDO77790.1 - 0.0044 17.3 0.9 0.0097 16.2 0.9 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDO77790.1 - 0.011 15.6 0.7 0.017 15.0 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CDO77790.1 - 0.016 15.1 0.7 0.024 14.5 0.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CDO77790.1 - 0.02 14.6 0.8 0.035 13.9 0.8 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CDO77790.1 - 0.065 13.3 0.3 0.09 12.8 0.2 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Retrotrans_gag PF03732.17 CDO77791.1 - 9e-13 48.3 0.0 3.2e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO77791.1 - 6.2e-09 35.7 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Apt1 PF10351.9 CDO77791.1 - 2.1 7.1 7.2 3.1 6.6 7.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM199X PF15814.5 CDO77791.1 - 2.5 7.1 10.6 3.9 6.4 10.6 1.2 1 0 0 1 1 1 0 Protein family FAM199X NPR3 PF03666.13 CDO77791.1 - 3.9 6.2 5.7 6.5 5.4 5.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2057 PF09829.9 CDO77792.1 - 0.11 12.7 0.6 1.2 9.3 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Myb_DNA-bind_3 PF12776.7 CDO77796.1 - 0.00037 21.4 0.0 0.0068 17.4 0.0 2.4 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain CAP_N PF01213.19 CDO77797.1 - 0.071 12.6 2.1 0.092 12.2 2.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Peptidase_S9 PF00326.21 CDO77798.1 - 1e-44 152.6 0.2 1.7e-44 151.8 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 CDO77798.1 - 0.00025 19.8 0.2 0.0024 16.6 0.2 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 CDO77798.1 - 0.00043 20.0 0.2 0.68 9.5 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 CDO77798.1 - 0.13 11.1 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family TRI5 PF06330.11 CDO77799.1 - 5.3e-07 28.8 0.0 6.9e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) RVT_1 PF00078.27 CDO77800.1 - 4.4e-11 42.7 0.2 1.1e-08 34.8 0.0 2.9 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO77800.1 - 2.6e-08 33.7 0.0 6.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 CDO77800.1 - 1.7e-06 28.7 0.2 5.6e-05 23.8 0.0 2.6 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CDO77800.1 - 0.041 13.4 0.1 0.12 11.9 0.1 1.9 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family zf-CCHC_6 PF15288.6 CDO77800.1 - 0.069 13.0 2.1 0.29 11.0 1.9 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 CDO77800.1 - 0.34 10.7 2.9 0.88 9.3 2.9 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger HIP1_clath_bdg PF16515.5 CDO77800.1 - 2.8 8.6 8.6 0.46 11.1 3.4 2.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 THOC7 PF05615.13 CDO77800.1 - 2.9 8.2 5.2 0.62 10.3 1.3 1.8 2 0 0 2 2 2 0 Tho complex subunit 7 rve PF00665.26 CDO77801.1 - 2.4e-18 66.4 0.3 5.7e-18 65.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO77801.1 - 3.9e-12 46.0 0.1 6.1e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO77801.1 - 3e-09 36.6 0.3 6.6e-09 35.5 0.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO77801.1 - 0.017 14.9 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF4820 PF16091.5 CDO77801.1 - 0.24 10.7 1.7 0.41 10.0 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Helicase_C PF00271.31 CDO77804.1 - 5.1e-13 49.3 0.0 1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCHC_6 PF15288.6 CDO77804.1 - 9.2e-06 25.4 1.4 2.4e-05 24.1 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle DEAD PF00270.29 CDO77804.1 - 0.00015 21.6 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AhpC-TSA_2 PF13911.6 CDO77804.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AAA_14 PF13173.6 CDO77804.1 - 0.006 16.6 0.0 0.082 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DDE_3 PF13358.6 CDO77805.1 - 2.6e-16 59.7 0.0 5e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease PAP2 PF01569.21 CDO77805.1 - 3.2e-16 59.4 1.7 7.6e-15 54.9 1.7 2.8 1 1 0 1 1 1 1 PAP2 superfamily HTH_Tnp_Tc3_2 PF01498.18 CDO77805.1 - 1e-06 28.9 1.3 1e-06 28.9 1.3 2.8 3 0 0 3 3 3 1 Transposase HTH_32 PF13565.6 CDO77805.1 - 0.028 15.0 3.0 0.028 15.0 3.0 3.1 3 1 1 4 4 4 0 Homeodomain-like domain Fungal_trans_2 PF11951.8 CDO77805.1 - 0.12 11.2 1.1 0.19 10.5 1.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain TilS_C PF11734.8 CDO77805.1 - 0.17 11.4 5.3 0.2 11.1 0.7 2.8 2 0 0 2 2 2 0 TilS substrate C-terminal domain RVT_1 PF00078.27 CDO77810.1 - 1.8e-15 57.1 0.0 2.7e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO77810.1 - 1.2e-08 35.2 0.0 2.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO77810.1 - 0.0017 19.0 0.0 0.0035 18.0 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Hydrolase_4 PF12146.8 CDO77811.1 - 9.6e-45 152.7 0.0 1.1e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CDO77811.1 - 8.9e-11 42.8 0.7 1.1e-10 42.5 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CDO77811.1 - 2.2e-09 37.3 0.0 2.3e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 CDO77811.1 - 0.046 12.4 0.0 0.26 9.9 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 CDO77811.1 - 0.13 11.7 0.0 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.16 CDO77812.1 - 2.1e-29 102.6 55.7 7.8e-29 100.7 55.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO77812.1 - 1.8e-21 76.2 18.4 3.4e-21 75.3 18.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hydrolase_4 PF12146.8 CDO77813.1 - 2.3e-38 131.8 0.0 5.2e-18 65.2 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CDO77813.1 - 5.6e-08 32.7 0.0 2.5e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO77813.1 - 1.2e-07 32.6 0.0 1.5e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 CDO77813.1 - 0.01 14.5 0.0 2.8 6.5 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) APH PF01636.23 CDO77815.1 - 2.3e-12 47.3 0.0 2.5e-11 43.9 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family ICMT PF04140.14 CDO77816.1 - 6e-13 49.0 1.5 9.5e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CDO77816.1 - 1.5e-11 44.6 0.4 1.5e-11 44.6 0.4 2.4 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 CDO77816.1 - 0.00056 18.8 0.3 0.00082 18.2 0.3 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CDO77816.1 - 0.073 12.6 0.2 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) p450 PF00067.22 CDO77817.1 - 7.9e-37 127.1 0.0 3.5e-36 124.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 CDO77818.1 - 8.4e-16 57.8 22.6 2e-09 36.9 16.6 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 CDO77818.1 - 0.047 12.0 0.4 0.082 11.2 0.4 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF659 PF04937.15 CDO77823.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) RUN PF02759.19 CDO77825.1 - 0.018 15.0 0.0 0.074 13.0 0.0 2.0 2 0 0 2 2 2 0 RUN domain RNase_PH PF01138.21 CDO77826.1 - 0.096 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 GRAB PF10375.9 CDO77827.1 - 9.1e-07 28.5 1.2 1.7e-06 27.7 1.2 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.20 CDO77827.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 GRIP domain LPP PF04728.13 CDO77827.1 - 8.5 6.8 9.5 0.42 11.0 1.7 2.9 3 1 1 4 4 4 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 CDO77827.1 - 9.4 6.3 12.1 6.8 6.8 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) F-box-like PF12937.7 CDO77828.1 - 7.1e-08 32.2 0.1 2.2e-07 30.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like APH PF01636.23 CDO77830.1 - 1.7e-12 47.8 0.2 4.8e-12 46.3 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CDO77830.1 - 9.1e-08 31.9 0.0 3.3e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 CDO77830.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.14 CDO77830.1 - 0.13 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CDO77831.1 - 1.3e-10 40.6 0.4 1.9e-10 40.1 0.4 1.2 1 0 0 1 1 1 1 Fungal protein kinase MAD PF05557.13 CDO77832.1 - 4.1e-55 187.4 68.0 9.5e-55 186.2 68.0 1.4 1 1 0 1 1 1 1 Mitotic checkpoint protein DUF2935 PF11155.8 CDO77832.1 - 0.00094 19.5 4.8 0.15 12.4 2.1 4.3 1 1 1 2 2 2 1 Domain of unknown function (DUF2935) DUF4887 PF16228.5 CDO77832.1 - 1.3 9.1 12.7 0.11 12.7 6.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4887) USP8_interact PF08941.10 CDO77832.1 - 3.2 7.6 22.2 0.22 11.3 1.3 4.6 3 1 2 5 5 5 0 USP8 interacting DUF262 PF03235.14 CDO77833.1 - 2e-14 54.3 0.1 6e-14 52.8 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF262 Peptidase_S64 PF08192.11 CDO77834.1 - 0.00035 19.2 0.0 0.00062 18.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S64 TPR_2 PF07719.17 CDO77835.1 - 1.4e-09 37.3 8.0 0.00034 20.5 2.9 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH_4 PF18044.1 CDO77835.1 - 3.7e-09 36.2 13.7 7.4e-05 22.4 0.7 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger TPR_1 PF00515.28 CDO77835.1 - 7.9e-08 31.8 3.9 0.069 13.0 2.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CDO77835.1 - 8.9e-05 22.6 5.6 8.9e-05 22.6 5.6 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-CCCH PF00642.24 CDO77835.1 - 0.00011 22.0 10.9 0.02 14.8 0.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_19 PF14559.6 CDO77835.1 - 0.00022 21.7 6.2 0.39 11.3 2.8 3.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDO77835.1 - 0.0012 19.5 30.0 0.02 15.5 3.5 3.9 4 1 1 5 5 3 2 Tetratricopeptide repeat zf_CCCH_4 PF18345.1 CDO77835.1 - 0.0017 18.4 14.0 0.043 13.9 0.3 2.8 2 1 0 2 2 2 2 Zinc finger domain TPR_11 PF13414.6 CDO77835.1 - 0.0019 17.8 0.5 0.016 14.9 0.3 2.5 2 0 0 2 2 2 1 TPR repeat zf-CCCH_2 PF14608.6 CDO77835.1 - 0.0046 17.4 11.2 0.29 11.6 6.0 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CDO77835.1 - 0.029 14.6 2.9 0.064 13.5 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger containing family PAM2 PF07145.15 CDO77835.1 - 0.031 13.9 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Ataxin-2 C-terminal region IMUP PF15761.5 CDO77835.1 - 0.042 14.5 0.5 0.14 12.9 0.5 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein TPR_14 PF13428.6 CDO77835.1 - 0.061 14.2 0.5 0.061 14.2 0.5 5.6 4 1 2 6 6 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDO77835.1 - 0.063 13.7 1.8 29 5.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2194 PF09960.9 CDO77835.1 - 0.099 11.0 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) ANAPC3 PF12895.7 CDO77835.1 - 0.12 12.7 3.4 0.3 11.3 2.2 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Torus PF16131.5 CDO77835.1 - 0.48 11.1 7.0 7.7 7.3 2.1 2.6 1 1 1 2 2 2 0 Torus domain TPR_12 PF13424.6 CDO77835.1 - 0.61 10.4 13.0 1.4 9.2 3.6 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_phi PF04931.13 CDO77836.1 - 0.63 8.1 2.9 0.87 7.6 2.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_25 PF13649.6 CDO77840.1 - 5.3e-10 39.9 0.0 3e-09 37.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CDO77840.1 - 7.3e-08 33.0 0.0 5.1e-07 30.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO77840.1 - 1.2e-07 32.4 0.0 2.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CDO77840.1 - 2.3e-07 30.4 0.0 3e-06 26.8 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CDO77840.1 - 1.7e-06 28.0 0.0 4.8e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO77840.1 - 3.5e-06 26.9 0.0 0.00024 21.0 0.0 2.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.16 CDO77840.1 - 0.037 12.6 0.0 0.8 8.2 0.0 2.3 3 0 0 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NNMT_PNMT_TEMT PF01234.17 CDO77840.1 - 0.17 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family EF-hand_6 PF13405.6 CDO77841.1 - 5.4e-23 78.9 0.3 2.5e-06 27.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 CDO77841.1 - 6.9e-23 78.4 0.5 7e-06 25.2 0.0 4.8 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CDO77841.1 - 6.8e-22 77.7 0.5 2.2e-09 37.6 0.3 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CDO77841.1 - 1.9e-18 65.0 0.1 0.0001 21.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CDO77841.1 - 4.3e-16 58.5 1.0 5.2e-08 32.6 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CDO77841.1 - 0.0015 18.8 0.1 4.1 7.8 0.0 3.2 3 1 0 3 3 3 2 EF-hand domain Asp_protease_2 PF13650.6 CDO77844.1 - 0.072 13.7 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Transposase_21 PF02992.14 CDO77845.1 - 1.3e-13 50.7 0.0 6.5e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 DUF3446 PF11928.8 CDO77845.1 - 1.1 9.7 6.9 13 6.2 0.7 3.0 2 0 0 2 2 2 0 Early growth response N-terminal domain zinc_ribbon_2 PF13240.6 CDO77845.1 - 8.9 6.2 7.9 1.1 9.1 1.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RVT_1 PF00078.27 CDO77846.1 - 1.4e-21 77.1 0.0 2.3e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO77846.1 - 3.1e-06 27.4 0.0 6.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.6 CDO77846.1 - 0.00098 19.0 0.1 0.06 13.2 0.1 2.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Helicase_C PF00271.31 CDO77848.1 - 1e-10 41.9 0.0 2.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CDO77848.1 - 6.3e-08 32.6 0.4 8.1e-07 29.0 0.4 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDO77848.1 - 6.2e-06 26.3 0.0 2.4e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Sugarporin_N PF11471.8 CDO77848.1 - 0.076 13.0 0.3 0.2 11.7 0.3 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Transferase PF02458.15 CDO77851.1 - 0.00029 19.6 0.0 0.00037 19.3 0.0 1.1 1 0 0 1 1 1 1 Transferase family TAL_FSA PF00923.19 CDO77851.1 - 0.12 11.7 0.0 8.1 5.7 0.0 2.1 1 1 0 2 2 2 0 Transaldolase/Fructose-6-phosphate aldolase PGM_PMM_II PF02879.16 CDO77852.1 - 2.5e-21 76.2 0.0 8.9e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.16 CDO77852.1 - 5.2e-16 58.6 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CDO77852.1 - 1.3e-15 57.6 0.0 2.4e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CDO77852.1 - 5e-06 26.6 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MCM_bind PF09739.9 CDO77853.1 - 3.5e-73 247.0 0.0 9e-72 242.4 0.0 2.0 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor Myb_DNA-bind_4 PF13837.6 CDO77854.1 - 5.4e-09 36.3 0.1 1e-08 35.5 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CDO77854.1 - 1.1e-08 36.0 0.0 1.7e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO77854.1 - 0.00041 20.4 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CDO77854.1 - 0.014 15.6 0.2 0.03 14.5 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain TAP42 PF04177.12 CDO77854.1 - 0.054 12.6 0.7 0.092 11.9 0.7 1.3 1 0 0 1 1 1 0 TAP42-like family TAL_effector PF03377.13 CDO77854.1 - 0.077 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 TAL effector repeat Myb_DNA-bind_6 PF13921.6 CDO77854.1 - 0.1 12.9 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain CENP-B_dimeris PF09026.10 CDO77854.1 - 0.36 11.2 9.0 0.74 10.2 9.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 CDO77854.1 - 1.1 7.2 5.7 1.9 6.5 5.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi DDE_Tnp_4 PF13359.6 CDO77855.1 - 4.7e-09 36.1 0.0 9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 CDO77855.1 - 6.6e-05 22.6 0.1 0.0001 22.0 0.1 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO77855.1 - 0.00069 19.9 0.1 0.0016 18.7 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 CDO77855.1 - 0.0069 16.0 0.1 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain HTH_38 PF13936.6 CDO77855.1 - 0.14 12.0 0.6 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Bac_DnaA_C PF08299.11 CDO77855.1 - 0.17 12.0 0.2 0.52 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein helix-turn-helix UVR PF02151.19 CDO77855.1 - 0.26 11.1 2.3 0.57 10.0 2.3 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif Myb_DNA-bind_3 PF12776.7 CDO77857.1 - 3.2e-08 34.4 0.0 8.1e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Thiol_cytolys_C PF17440.2 CDO77857.1 - 0.19 11.9 0.6 2.5 8.3 0.3 2.2 1 1 1 2 2 2 0 Thiol-activated cytolysin beta sandwich domain Asp PF00026.23 CDO77858.1 - 7.8e-12 45.2 0.1 6e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp PF00026.23 CDO77859.1 - 3.2e-13 49.8 6.6 2.4e-10 40.3 6.6 3.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CDO77859.1 - 3.2e-08 34.1 1.1 2.6e-07 31.2 0.3 2.7 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 CDO77859.1 - 0.00028 21.4 0.1 0.0013 19.3 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 CDO77859.1 - 0.19 12.0 2.6 15 5.7 0.1 2.5 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal DUF1180 PF06679.12 CDO77859.1 - 0.67 10.3 3.6 0.54 10.7 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) zf-MYND PF01753.18 CDO77861.1 - 7.9e-11 41.9 15.0 1.2e-10 41.3 15.0 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CDO77861.1 - 0.065 13.6 7.1 0.12 12.6 7.1 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 CDO77861.1 - 0.94 9.4 7.7 1.4 8.8 7.7 1.3 1 0 0 1 1 1 0 HIT zinc finger PNP_UDP_1 PF01048.20 CDO77863.1 - 6.7e-39 133.5 0.1 9.1e-39 133.1 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily RVT_2 PF07727.14 CDO77864.1 - 4.6e-73 245.8 0.0 5.9e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CDO77864.1 - 0.03 13.8 0.1 0.073 12.6 0.1 1.7 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3275 PF11679.8 CDO77864.1 - 2.5 8.1 5.2 5.2 7.0 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Transposase_21 PF02992.14 CDO77865.1 - 2.7e-09 36.6 0.0 5.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 RVT_2 PF07727.14 CDO77867.1 - 5.9e-19 68.7 0.0 9.2e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO77867.1 - 0.00045 20.4 0.0 0.00079 19.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_4 PF13359.6 CDO77868.1 - 7e-18 64.8 0.0 8.7e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO77868.1 - 1.4e-05 24.9 0.0 3.4e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO77868.1 - 0.0044 16.6 0.0 0.0077 15.9 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO77868.1 - 0.031 14.6 0.1 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 CDO77869.1 - 0.00032 21.6 0.0 0.00077 20.4 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO77869.1 - 0.00059 20.2 0.3 0.0017 18.7 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain ATP_bind_1 PF03029.17 CDO77870.1 - 1.7e-73 247.4 0.0 2.1e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CDO77870.1 - 0.14 12.3 0.2 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain GST_N_3 PF13417.6 CDO77871.1 - 8.5e-11 42.1 0.0 1.5e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO77871.1 - 5e-08 33.1 0.0 8.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO77871.1 - 1.8e-07 31.4 0.1 4.8e-07 30.0 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO77871.1 - 0.0002 21.3 0.2 0.00041 20.3 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldo_ket_red PF00248.21 CDO77872.1 - 3.9e-63 213.4 0.0 4.9e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NAF PF03822.14 CDO77872.1 - 0.17 12.1 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 NAF domain Aldo_ket_red PF00248.21 CDO77873.1 - 7e-71 238.8 0.0 8.1e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CMAS PF02353.20 CDO77875.1 - 3.9e-65 219.9 0.0 4.8e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CDO77875.1 - 3.3e-11 43.7 0.0 3.8e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CDO77875.1 - 1.2e-10 42.0 0.0 6.3e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CDO77875.1 - 6.2e-10 39.2 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CDO77875.1 - 4.7e-07 30.5 0.0 1e-06 29.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CDO77875.1 - 0.00015 21.6 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 CDO77875.1 - 0.00019 21.1 0.0 0.00043 19.9 0.0 1.5 2 0 0 2 2 2 1 Histone methylation protein DOT1 MTS PF05175.14 CDO77875.1 - 0.0052 16.4 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CDO77875.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CDO77875.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain YIF1 PF03878.15 CDO77876.1 - 5.7e-91 304.3 0.5 6.9e-91 304.0 0.5 1.0 1 0 0 1 1 1 1 YIF1 Phage_holin_2_1 PF04971.12 CDO77876.1 - 0.19 11.7 0.7 0.47 10.5 0.7 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S rve PF00665.26 CDO77878.1 - 2.4e-18 66.5 0.3 5.6e-18 65.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO77878.1 - 3.9e-12 46.0 0.1 6e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CDO77878.1 - 3e-09 36.6 0.3 6.5e-09 35.5 0.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO77878.1 - 0.017 14.9 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF4820 PF16091.5 CDO77878.1 - 0.23 10.8 1.7 0.4 10.0 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RT_RNaseH PF17917.1 CDO77880.1 - 2.1e-38 130.8 0.0 3.4e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO77880.1 - 6.4e-35 119.2 0.0 1.2e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO77880.1 - 1.2e-27 96.9 0.0 2e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEAD PF00270.29 CDO77881.1 - 3.3e-16 59.5 0.0 6.4e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CDO77881.1 - 1.8e-07 31.3 0.0 3.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CDO77881.1 - 3.3e-06 27.4 0.0 0.00027 21.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Jiv90 PF14901.6 CDO77882.1 - 0.081 13.1 0.2 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone DEC-1_N PF04625.13 CDO77883.1 - 0.7 8.8 4.9 0.25 10.3 1.2 1.9 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Methyltransf_25 PF13649.6 CDO77885.1 - 0.00039 21.1 0.0 0.0045 17.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Plavaka PF18759.1 CDO77886.1 - 9.7e-30 103.9 0.0 6.3e-21 74.9 0.0 2.1 1 1 1 2 2 2 2 Plavaka transposase ATP_bind_1 PF03029.17 CDO77889.1 - 1.7e-73 247.4 0.0 2.1e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CDO77889.1 - 0.14 12.3 0.2 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain GST_N_3 PF13417.6 CDO77890.1 - 8.5e-11 42.1 0.0 1.5e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO77890.1 - 5e-08 33.1 0.0 8.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO77890.1 - 1.8e-07 31.4 0.1 4.8e-07 30.0 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO77890.1 - 0.0002 21.3 0.2 0.00041 20.3 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DDE_3 PF13358.6 CDO77891.1 - 1.9e-09 37.4 0.2 2.5e-09 37.0 0.2 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF2550 PF10739.9 CDO77892.1 - 0.092 12.8 0.2 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2550) Peroxin-13_N PF04088.13 CDO77893.1 - 1.7e-45 154.9 0.0 2.4e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 CDO77893.1 - 1.8e-11 43.5 2.2 7.1e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CDO77893.1 - 1.3e-09 37.6 0.0 2.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CDO77893.1 - 1.5e-08 34.4 0.6 3.3e-08 33.2 0.6 1.6 1 1 0 1 1 1 1 Variant SH3 domain PIF1 PF05970.14 CDO77896.1 - 2.4e-113 379.0 0.0 3.3e-113 378.6 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 CDO77896.1 - 2.7e-59 200.6 0.1 4.7e-59 199.8 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 CDO77896.1 - 2.2e-09 37.3 0.0 3.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CDO77896.1 - 0.0014 18.9 0.0 0.0053 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CDO77896.1 - 0.0053 14.8 0.0 0.0085 14.1 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 CDO77896.1 - 0.0055 17.1 0.0 0.019 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.6 CDO77896.1 - 0.007 16.2 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2791 PF10923.8 CDO77896.1 - 0.035 13.0 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_5 PF07728.14 CDO77896.1 - 0.057 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 CDO77896.1 - 0.098 12.4 0.0 1.4 8.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CDO77896.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_C48 PF02902.19 CDO77898.1 - 0.0048 16.8 0.4 0.0077 16.1 0.4 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Zn_clus PF00172.18 CDO77899.1 - 0.027 14.6 7.2 0.048 13.8 7.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1266 PF06889.11 CDO77899.1 - 7.2 6.6 7.8 3.6 7.6 4.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1266) AAA_11 PF13086.6 CDO77899.1 - 7.9 6.2 13.0 2.1 8.1 0.2 2.3 2 0 0 2 2 2 0 AAA domain rve PF00665.26 CDO77900.1 - 4.9e-14 52.5 0.0 9e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO77900.1 - 3.6e-07 30.0 0.0 6.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ferrochelatase PF00762.19 CDO77900.1 - 0.048 12.7 0.1 1.4 7.9 0.0 2.1 1 1 1 2 2 2 0 Ferrochelatase RT_RNaseH_2 PF17919.1 CDO77901.1 - 1e-30 105.7 0.0 1.3e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO77901.1 - 4.1e-21 75.2 0.0 5.7e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Transposase_21 PF02992.14 CDO77902.1 - 2e-11 43.5 0.0 3.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 CDO77902.1 - 0.16 11.6 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) RVT_1 PF00078.27 CDO77903.1 - 3.5e-23 82.3 0.0 5.8e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO77903.1 - 2.6e-08 34.1 0.0 5.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO77903.1 - 0.00012 22.7 0.0 0.00025 21.7 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase VP4_2 PF08935.10 CDO77903.1 - 0.33 11.6 0.7 2.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Viral protein VP4 subunit MFS_1 PF07690.16 CDO77904.1 - 7.2e-29 100.8 57.3 3e-20 72.4 29.3 3.3 2 2 1 3 3 3 2 Major Facilitator Superfamily MBOAT_2 PF13813.6 CDO77904.1 - 7.2e-07 29.4 1.9 4e-06 27.0 0.6 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Sugar_tr PF00083.24 CDO77904.1 - 0.00018 20.5 26.8 0.0042 16.0 5.2 3.6 4 0 0 4 4 4 3 Sugar (and other) transporter MFS_1_like PF12832.7 CDO77904.1 - 0.055 12.3 23.9 0.38 9.5 10.5 2.7 1 1 1 2 2 2 0 MFS_1 like family p450 PF00067.22 CDO77905.1 - 1e-64 219.0 0.0 9.6e-64 215.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 M20_dimer PF07687.14 CDO77905.1 - 1.7e-06 27.9 0.0 4.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Epimerase PF01370.21 CDO77906.1 - 3.4e-51 174.0 0.0 5.1e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CDO77906.1 - 1.5e-14 54.2 0.0 1.3e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CDO77906.1 - 5.8e-06 25.7 1.1 0.00071 18.8 0.9 3.1 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CDO77906.1 - 5e-05 22.6 0.0 9.8e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 CDO77906.1 - 0.023 13.7 0.0 0.059 12.4 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CDO77907.1 - 3.3e-157 523.1 0.0 3.8e-157 522.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CDO77907.1 - 4.9e-72 242.3 0.0 6.3e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CDO77907.1 - 0.0002 20.6 0.0 0.00031 20.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CDO77907.1 - 0.0044 16.2 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CDO77907.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 CDO77907.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding MFS_1 PF07690.16 CDO77908.1 - 3.7e-40 137.9 60.8 1.3e-31 109.8 35.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO77908.1 - 4.8e-06 25.7 27.1 2.5e-05 23.3 13.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 CDO77908.1 - 0.00019 20.5 23.6 0.00041 19.3 10.4 3.1 1 1 2 3 3 3 2 MFS_1 like family Pkinase PF00069.25 CDO77909.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CDO77909.1 - 0.0095 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.27 CDO77910.1 - 2.3e-35 122.1 0.0 3.6e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO77910.1 - 6.4e-21 74.4 0.0 1.5e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDO77910.1 - 2e-09 37.3 1.0 5.5e-09 35.9 1.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.24 CDO77910.1 - 3.5e-09 37.0 0.0 7.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO77910.1 - 0.0049 17.6 0.5 0.013 16.2 0.5 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.23 CDO77911.1 - 0.00077 19.4 4.1 0.00077 19.4 4.1 3.3 3 1 0 3 3 3 2 Zinc knuckle zf-CCHC_6 PF15288.6 CDO77911.1 - 0.0093 15.8 0.6 0.0093 15.8 0.6 3.7 3 0 0 3 3 3 2 Zinc knuckle Med25_VWA PF11265.8 CDO77913.1 - 2.5e-05 24.2 0.0 5.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Adaptin_binding PF10199.9 CDO77913.1 - 0.0027 18.3 0.0 2 9.0 0.0 3.4 4 1 0 4 4 4 2 Alpha and gamma adaptin binding protein p34 Macro_2 PF14519.6 CDO77914.1 - 0.00043 19.7 0.1 0.0016 17.8 0.1 1.8 1 1 0 1 1 1 1 Macro-like domain p450 PF00067.22 CDO77915.1 - 1e-11 44.3 0.0 1.2e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.18 CDO77916.1 - 3.2e-47 161.3 0.0 4e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 CDO77916.1 - 1e-13 51.0 6.3 1e-13 51.0 6.3 3.5 5 0 0 5 5 5 1 Fungal cellulose binding domain Ribosomal_L30 PF00327.20 CDO77917.1 - 9.6e-13 47.8 0.5 1.3e-12 47.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PTCB-BRCT PF12738.7 CDO77918.1 - 5.9e-19 67.8 0.0 1.1e-13 50.9 0.0 3.1 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 CDO77918.1 - 8.2e-10 38.9 0.0 1.1e-05 25.8 0.0 3.5 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CDO77918.1 - 0.0055 17.1 0.0 2.8 8.4 0.0 3.0 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain PITH PF06201.13 CDO77919.1 - 1.7e-36 125.8 0.0 2.1e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain FliO PF04347.13 CDO77921.1 - 0.043 14.1 0.1 0.13 12.6 0.1 1.8 1 1 0 1 1 1 0 Flagellar biosynthesis protein, FliO VCPO_N PF17897.1 CDO77922.1 - 1.9 8.2 6.0 0.62 9.8 1.5 2.3 1 1 2 3 3 3 0 Vanadium chloroperoxidase N-terminal domain GST_C_6 PF17171.4 CDO77923.1 - 5.9e-14 51.6 0.0 2e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CDO77923.1 - 0.00029 20.8 0.1 0.00098 19.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CDO77923.1 - 0.00085 20.0 0.0 0.0096 16.6 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain SAM35 PF10806.8 CDO77923.1 - 0.2 11.9 0.2 0.39 11.0 0.2 1.5 1 0 0 1 1 1 0 SAM35, subunit of SAM coomplex zf-RING_5 PF14634.6 CDO77924.1 - 1.7e-06 27.9 13.4 1.2e-05 25.1 5.1 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CDO77924.1 - 1.6e-05 24.6 6.8 1.6e-05 24.6 6.8 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CDO77924.1 - 2.2e-05 24.4 5.2 2.2e-05 24.4 5.2 2.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDO77924.1 - 2.7e-05 24.4 5.9 2.7e-05 24.4 5.9 2.7 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 CDO77924.1 - 3.1e-05 24.2 2.7 9.9e-05 22.6 2.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CDO77924.1 - 0.00011 22.0 4.2 0.00011 22.0 4.2 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CDO77924.1 - 0.00035 20.4 5.1 0.00035 20.4 5.1 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CDO77924.1 - 0.0074 16.1 1.8 0.0074 16.1 1.8 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 CDO77924.1 - 0.008 16.3 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Prok-RING_4 PF14447.6 CDO77924.1 - 0.017 14.9 5.3 0.017 14.9 5.3 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CDO77924.1 - 0.025 14.6 1.4 0.067 13.2 1.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CDO77924.1 - 0.4 10.9 13.1 0.07 13.3 5.7 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.7 CDO77924.1 - 7 6.8 9.2 3 7.9 0.5 2.7 2 1 0 2 2 2 0 Double zinc ribbon Brix PF04427.18 CDO77925.1 - 3.4e-37 128.4 0.0 4.7e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nucleopor_Nup85 PF07575.13 CDO77925.1 - 0.057 12.0 0.1 0.075 11.6 0.1 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin zf-RING_UBOX PF13445.6 CDO77926.1 - 5.4e-07 29.5 3.3 2e-06 27.7 3.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CDO77926.1 - 8e-07 29.3 6.6 1.4e-06 28.5 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CDO77926.1 - 2.5e-06 27.2 5.1 4.4e-06 26.5 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CDO77926.1 - 1e-05 25.4 7.4 2.2e-05 24.3 7.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CDO77926.1 - 0.00025 20.9 6.8 0.00049 19.9 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CDO77926.1 - 0.00053 19.7 2.2 0.00053 19.7 2.2 2.5 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CDO77926.1 - 0.0015 18.4 8.4 0.0037 17.1 8.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CDO77926.1 - 0.0038 17.4 7.7 0.0088 16.2 7.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Sld7_C PF18596.1 CDO77926.1 - 0.0042 17.2 1.7 0.0097 16.0 1.5 1.7 1 1 0 1 1 1 1 Sld7 C-terminal domain zf-RING_10 PF16685.5 CDO77926.1 - 0.0067 16.5 3.0 0.014 15.5 3.0 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 DUF5318 PF17249.2 CDO77926.1 - 0.0095 15.7 1.2 0.019 14.8 0.1 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5318) IKBKB_SDD PF18397.1 CDO77926.1 - 0.013 14.8 6.8 0.017 14.4 6.8 1.2 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain DUF2462 PF09495.10 CDO77926.1 - 0.036 14.8 0.5 0.036 14.8 0.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2462) Prok-RING_4 PF14447.6 CDO77926.1 - 0.038 13.8 6.6 0.098 12.5 6.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Spore_III_AB PF09548.10 CDO77926.1 - 0.042 14.0 0.5 0.042 14.0 0.5 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) zf-RING_6 PF14835.6 CDO77926.1 - 0.045 13.6 2.8 0.081 12.8 2.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FapA PF03961.13 CDO77926.1 - 0.061 11.9 5.3 0.076 11.6 5.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cytochrom_B562 PF07361.11 CDO77926.1 - 0.067 13.9 2.2 0.067 13.9 2.2 2.9 2 1 1 3 3 2 0 Cytochrome b562 Zn_ribbon_17 PF17120.5 CDO77926.1 - 0.073 12.7 4.5 0.13 11.9 4.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Spc7 PF08317.11 CDO77926.1 - 0.22 10.4 14.1 0.35 9.7 14.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 CDO77926.1 - 0.3 10.6 8.7 0.39 10.2 8.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DHR10 PF18595.1 CDO77926.1 - 0.33 11.0 22.2 0.47 10.5 11.5 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Borrelia_P83 PF05262.11 CDO77926.1 - 0.36 9.3 14.4 0.43 9.0 14.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein YabA PF06156.13 CDO77926.1 - 0.37 11.4 6.4 3.4 8.4 1.7 2.4 2 0 0 2 2 2 0 Initiation control protein YabA Golgin_A5 PF09787.9 CDO77926.1 - 0.68 9.3 15.7 1.1 8.7 14.7 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 TMF_TATA_bd PF12325.8 CDO77926.1 - 2.3 8.5 16.5 1.3 9.2 12.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 CDO77926.1 - 2.5 8.7 19.0 0.059 13.9 6.2 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region zf-RING_4 PF14570.6 CDO77926.1 - 2.5 8.0 6.8 5.9 6.8 6.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Macoilin PF09726.9 CDO77926.1 - 6.7 5.1 16.0 25 3.2 16.0 1.7 1 1 0 1 1 1 0 Macoilin family KH_1 PF00013.29 CDO77928.1 - 9.1e-44 147.1 8.0 1.3e-14 53.7 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CDO77928.1 - 1.4e-15 56.9 8.1 5.8e-06 26.0 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CDO77928.1 - 3.7e-05 23.5 1.7 0.55 10.1 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 CDO77928.1 - 0.0068 16.5 6.8 2.3 8.4 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain CPDase PF07823.11 CDO77930.1 - 1e-09 38.4 3.3 1.3e-06 28.2 0.1 3.0 1 1 1 2 2 2 2 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 CDO77930.1 - 0.00032 20.6 0.8 0.028 14.3 0.2 2.3 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily RcpC PF16976.5 CDO77930.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB DUF1776 PF08643.10 CDO77931.1 - 1.3e-14 54.2 0.0 3.2e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF883 PF05957.13 CDO77931.1 - 0.016 15.8 0.1 0.089 13.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TRAM_LAG1_CLN8 PF03798.16 CDO77932.1 - 4.9e-29 101.5 12.2 4.9e-29 101.5 12.2 1.6 2 0 0 2 2 2 1 TLC domain DDE_3 PF13358.6 CDO77934.1 - 2.3e-07 30.7 0.0 0.00015 21.5 0.0 2.5 2 0 0 2 2 2 2 DDE superfamily endonuclease DDE_1 PF03184.19 CDO77935.1 - 4.5e-19 68.8 0.1 4.1e-13 49.4 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease Cas_Cas6 PF01881.16 CDO77935.1 - 0.14 12.7 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas6 Aldedh PF00171.22 CDO77936.1 - 2.4e-57 194.5 0.0 4.5e-35 121.1 0.0 2.8 2 1 1 3 3 3 3 Aldehyde dehydrogenase family LuxC PF05893.14 CDO77936.1 - 0.0047 16.0 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) p450 PF00067.22 CDO77937.1 - 1.4e-33 116.3 0.1 7.9e-32 110.6 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.14 CDO77940.1 - 3.7e-49 167.4 0.0 4.8e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RVT_2 PF07727.14 CDO77941.1 - 3.3e-31 108.8 0.1 4.4e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SLBP_RNA_bind PF15247.6 CDO77942.1 - 0.044 13.9 0.4 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Asp PF00026.23 CDO77943.1 - 2.7e-73 247.1 7.7 3.2e-73 246.9 7.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO77943.1 - 1e-12 48.7 3.0 3.3e-11 43.7 3.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO77943.1 - 0.026 15.2 0.3 0.38 11.4 0.2 2.9 3 1 0 3 3 3 0 Aspartyl protease TAXi_C PF14541.6 CDO77943.1 - 0.027 14.2 0.1 0.094 12.5 0.0 1.9 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal PSK_trans_fac PF07704.11 CDO77946.1 - 0.099 13.4 0.0 0.43 11.4 0.0 2.1 2 0 0 2 2 2 0 Rv0623-like transcription factor Mito_carr PF00153.27 CDO77947.1 - 1.6e-33 114.5 0.0 1.4e-16 60.2 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein CbtA PF09490.10 CDO77947.1 - 8.5e-05 22.4 3.2 0.057 13.2 0.2 2.1 2 0 0 2 2 2 2 Probable cobalt transporter subunit (CbtA) Ribosomal_60s PF00428.19 CDO77947.1 - 0.011 16.4 3.3 0.011 16.4 3.3 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chorismate_synt PF01264.21 CDO77947.1 - 0.033 12.9 0.0 0.048 12.4 0.0 1.1 1 0 0 1 1 1 0 Chorismate synthase TraQ PF09679.10 CDO77947.1 - 0.12 12.3 2.1 1.3 9.0 0.2 2.6 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) Arrestin_N PF00339.29 CDO77950.1 - 0.0002 21.4 0.1 0.0046 17.0 0.1 2.5 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DDE_Tnp_4 PF13359.6 CDO77951.1 - 1.4e-09 37.8 0.0 8.2e-08 32.1 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 CDO77951.1 - 0.0055 16.3 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO77951.1 - 0.019 15.4 0.0 0.087 13.2 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 CDO77952.1 - 0.00013 22.8 0.1 0.00035 21.5 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO77952.1 - 0.001 19.4 0.4 0.0027 18.0 0.2 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain NUDIX PF00293.28 CDO77954.1 - 0.0017 18.4 0.5 0.0042 17.1 0.3 2.1 1 1 0 1 1 1 1 NUDIX domain FA_desaturase PF00487.24 CDO77955.1 - 7.2e-24 85.0 16.4 8.2e-24 84.8 15.6 1.4 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.10 CDO77955.1 - 1.1e-18 66.4 0.4 1.8e-18 65.7 0.4 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) zf-C2H2 PF00096.26 CDO77956.1 - 0.068 13.7 0.4 0.3 11.6 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4746 PF15928.5 CDO77956.1 - 2.8 7.3 7.5 4.9 6.5 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pkinase PF00069.25 CDO77957.1 - 1.2e-61 208.4 0.0 1.6e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO77957.1 - 3.4e-25 88.8 0.0 4.9e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CDO77957.1 - 0.029 13.3 0.3 0.04 12.9 0.3 1.1 1 0 0 1 1 1 0 Haspin like kinase domain NARP1 PF12569.8 CDO77958.1 - 4.3e-155 517.5 3.8 2.8e-151 505.0 0.1 3.0 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CDO77958.1 - 1.9e-16 58.8 12.6 0.0028 17.7 0.0 9.1 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 CDO77958.1 - 8.9e-13 47.5 2.0 0.00052 19.7 0.2 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 CDO77958.1 - 3.3e-12 46.9 23.0 6.2e-05 23.6 0.9 9.1 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CDO77958.1 - 9.5e-12 44.7 24.1 0.00027 21.5 0.2 10.9 6 2 6 12 12 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 CDO77958.1 - 1.4e-11 44.7 19.6 0.053 14.0 0.9 8.5 8 1 1 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CDO77958.1 - 8.7e-11 41.9 1.0 0.056 13.7 0.0 5.1 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CDO77958.1 - 3.8e-10 39.3 2.6 0.00015 21.4 0.1 4.8 5 0 0 5 5 5 2 TPR repeat TPR_8 PF13181.6 CDO77958.1 - 7e-10 38.3 0.7 0.0051 16.9 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 CDO77958.1 - 7.5e-08 32.6 12.5 0.022 15.1 0.1 6.5 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CDO77958.1 - 4e-06 26.5 9.9 0.021 14.8 0.1 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 CDO77958.1 - 1.1e-05 25.6 10.3 0.025 15.2 0.5 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 CDO77958.1 - 2.6e-05 23.9 1.6 0.68 9.9 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 CDO77958.1 - 0.00016 21.8 19.7 0.82 9.9 1.0 6.6 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CDO77958.1 - 0.0015 19.0 12.8 56 4.7 0.0 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_17 PF13431.6 CDO77958.1 - 0.0049 17.2 3.8 36 5.0 0.0 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CDO77958.1 - 0.0055 16.8 5.7 0.43 10.7 0.0 5.0 5 1 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 CDO77958.1 - 1.5 9.3 10.7 5.2 7.5 0.6 4.2 4 1 0 4 4 4 0 Bacterial transcriptional activator domain HEAT_2 PF13646.6 CDO77959.1 - 0.0044 17.4 1.3 0.096 13.1 0.1 4.4 2 1 2 4 4 4 2 HEAT repeats DUF3385 PF11865.8 CDO77959.1 - 0.051 13.5 1.0 0.27 11.1 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) UNC45-central PF11701.8 CDO77959.1 - 0.34 10.9 6.0 0.26 11.2 0.3 3.3 3 1 1 4 4 4 0 Myosin-binding striated muscle assembly central HEAT PF02985.22 CDO77959.1 - 0.74 10.2 11.0 4.2 7.9 0.0 5.5 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.6 CDO77959.1 - 0.93 10.1 5.2 8.5 7.0 0.1 4.4 4 0 0 4 4 4 0 HEAT-like repeat Cwf_Cwc_15 PF04889.12 CDO77959.1 - 8.6 6.0 26.9 19 4.9 26.9 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cauli_AT PF03233.13 CDO77960.1 - 1.1 9.1 4.4 0.94 9.4 0.1 2.5 2 1 0 2 2 2 0 Aphid transmission protein Syntaxin-6_N PF09177.11 CDO77960.1 - 2 9.0 8.7 4.3 8.0 1.9 3.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF720 PF05302.11 CDO77960.1 - 6.6 6.6 8.9 1.8 8.4 3.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF720) Baculo_PEP_C PF04513.12 CDO77961.1 - 0.0042 17.1 1.8 1.9 8.5 0.1 2.7 2 1 0 3 3 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 CDO77961.1 - 0.0052 16.1 0.1 0.0052 16.1 0.1 2.6 3 1 0 3 3 3 1 Protein of unknown function (DUF3450) PI_PP_I PF18363.1 CDO77961.1 - 0.0056 16.8 0.5 0.41 10.9 0.0 3.3 3 2 1 4 4 2 1 Phosphoinositide phosphatase insertion domain ApoLp-III PF07464.11 CDO77961.1 - 0.01 16.0 8.2 0.087 12.9 0.2 3.6 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) CENP-F_leu_zip PF10473.9 CDO77961.1 - 0.012 15.6 11.2 0.29 11.1 0.6 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CobD_Cbib PF03186.13 CDO77961.1 - 0.012 14.9 1.6 0.019 14.2 1.6 1.3 1 0 0 1 1 1 0 CobD/Cbib protein HALZ PF02183.18 CDO77961.1 - 0.012 15.8 1.1 0.28 11.4 0.2 3.3 3 0 0 3 3 2 0 Homeobox associated leucine zipper DUF5082 PF16888.5 CDO77961.1 - 0.013 15.7 1.1 0.013 15.7 1.1 2.8 3 2 0 3 3 3 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 CDO77961.1 - 0.015 15.7 0.4 31 5.1 0.0 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Muted PF14942.6 CDO77961.1 - 0.027 14.8 1.0 0.027 14.8 1.0 2.9 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein DUF1664 PF07889.12 CDO77961.1 - 0.032 14.3 8.7 3.8 7.6 1.5 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4446 PF14584.6 CDO77961.1 - 0.071 13.1 6.9 0.64 10.0 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4446) Retrotrans_gag PF03732.17 CDO77961.1 - 0.075 13.3 5.2 0.16 12.3 0.1 3.5 3 2 1 4 4 4 0 Retrotransposon gag protein MCC-bdg_PDZ PF10506.9 CDO77961.1 - 0.086 12.9 2.7 2.7 8.1 0.4 2.9 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_TATA_bd PF12325.8 CDO77961.1 - 0.12 12.5 0.2 0.12 12.5 0.2 4.1 4 2 0 4 4 4 0 TATA element modulatory factor 1 TATA binding AP4E_app_platf PF14807.6 CDO77961.1 - 0.14 12.6 1.6 1.6 9.2 0.1 3.1 3 1 1 4 4 3 0 Adaptin AP4 complex epsilon appendage platform THOC7 PF05615.13 CDO77961.1 - 0.14 12.4 10.6 0.2 11.9 0.1 3.4 3 1 0 3 3 3 0 Tho complex subunit 7 DUF812 PF05667.11 CDO77961.1 - 0.16 10.8 11.9 0.12 11.2 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF812) PHA_synth_III_E PF09712.10 CDO77961.1 - 0.2 10.7 4.9 4 6.4 2.2 2.8 1 1 1 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Spc24 PF08286.11 CDO77961.1 - 0.29 11.4 4.9 2.9 8.2 0.3 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 CDO77961.1 - 0.31 9.9 11.0 1 8.2 1.3 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.8 CDO77961.1 - 0.34 8.4 12.6 0.19 9.2 3.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Prefoldin_2 PF01920.20 CDO77961.1 - 0.52 10.3 15.8 0.39 10.7 1.5 3.7 3 1 0 3 3 3 0 Prefoldin subunit Sec2p PF06428.11 CDO77961.1 - 0.54 10.3 9.8 2 8.5 1.4 2.9 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Syntaxin PF00804.25 CDO77961.1 - 0.77 9.4 10.2 16 5.1 0.1 3.3 3 0 0 3 3 3 0 Syntaxin LapA_dom PF06305.11 CDO77961.1 - 1 9.2 6.7 23 4.9 6.7 2.8 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2203 PF09969.9 CDO77961.1 - 1.6 9.5 9.9 6.6 7.5 0.8 3.4 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) FAM76 PF16046.5 CDO77961.1 - 1.6 8.0 6.9 1.1 8.6 2.1 2.2 2 0 0 2 2 2 0 FAM76 protein Cep57_MT_bd PF06657.13 CDO77961.1 - 2 9.0 0.0 2 9.0 0.0 3.9 4 1 0 4 4 3 0 Centrosome microtubule-binding domain of Cep57 ABC_tran_CTD PF16326.5 CDO77961.1 - 2.6 8.3 17.6 1.8 8.8 5.8 4.5 3 2 1 4 4 4 0 ABC transporter C-terminal domain BLOC1_2 PF10046.9 CDO77961.1 - 2.6 8.4 11.5 5.2 7.4 1.5 4.2 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V-SNARE PF05008.15 CDO77961.1 - 3.4 8.1 10.3 0.93 9.9 1.2 3.6 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Snapin_Pallidin PF14712.6 CDO77961.1 - 4.1 7.9 10.8 2.9 8.4 0.7 3.4 3 1 0 3 3 2 0 Snapin/Pallidin APG6_N PF17675.1 CDO77961.1 - 4.9 7.7 17.1 1.2 9.7 2.2 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 CDO77961.1 - 5.4 7.2 12.7 3.7 7.7 5.2 3.3 2 1 0 2 2 1 0 Centrosome localisation domain of PPC89 DUF4349 PF14257.6 CDO77961.1 - 8.2 5.8 14.9 0.58 9.6 2.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) TSC22 PF01166.18 CDO77962.1 - 0.0042 17.3 5.9 0.29 11.5 0.8 4.8 3 1 0 3 3 3 1 TSC-22/dip/bun family YabA PF06156.13 CDO77962.1 - 0.0091 16.6 3.6 0.0091 16.6 3.6 4.4 4 2 1 5 5 5 1 Initiation control protein YabA CLTH PF10607.9 CDO77962.1 - 0.025 14.5 2.6 0.041 13.8 0.1 2.6 3 0 0 3 3 3 0 CTLH/CRA C-terminal to LisH motif domain NRBF2 PF08961.10 CDO77962.1 - 0.029 14.0 0.7 0.029 14.0 0.7 2.4 2 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator GldM_N PF12081.8 CDO77962.1 - 0.035 14.2 12.0 1.1 9.3 0.6 3.3 2 2 1 3 3 3 0 GldM N-terminal domain ATP-synt_E_2 PF08112.11 CDO77962.1 - 0.076 13.3 0.8 0.26 11.6 0.0 2.3 3 0 0 3 3 3 0 ATP synthase epsilon subunit GPW_gp25 PF04965.14 CDO77962.1 - 0.11 12.3 1.6 0.34 10.7 0.1 2.6 3 0 0 3 3 3 0 Gene 25-like lysozyme DUF4315 PF14193.6 CDO77962.1 - 0.13 12.3 1.7 25 5.0 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) Casc1_N PF15927.5 CDO77962.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.9 3 1 0 3 3 3 0 Cancer susceptibility candidate 1 N-terminus Shugoshin_N PF07558.11 CDO77962.1 - 0.21 11.5 7.7 0.53 10.2 3.9 3.5 3 1 0 3 3 2 0 Shugoshin N-terminal coiled-coil region ESCRT-II PF05871.12 CDO77962.1 - 0.31 11.3 3.0 13 6.1 0.7 2.5 2 0 0 2 2 2 0 ESCRT-II complex subunit PCRF PF03462.18 CDO77962.1 - 0.59 10.0 19.1 0.082 12.8 2.2 4.0 3 1 1 4 4 4 0 PCRF domain bZIP_2 PF07716.15 CDO77962.1 - 1.4 9.1 9.4 1.1 9.4 2.3 4.0 2 1 2 4 4 4 0 Basic region leucine zipper Csm2_III-A PF03750.13 CDO77962.1 - 2.4 9.0 7.0 16 6.4 0.0 3.8 4 0 0 4 4 4 0 Csm2 Type III-A DUF883 PF05957.13 CDO77962.1 - 2.8 8.6 16.8 12 6.6 0.1 5.1 5 1 0 5 5 4 0 Bacterial protein of unknown function (DUF883) XkdW PF09636.10 CDO77962.1 - 2.9 8.0 8.3 2.1 8.5 0.8 3.0 3 1 0 3 3 3 0 XkdW protein DUF5082 PF16888.5 CDO77962.1 - 5.1 7.4 23.6 0.12 12.6 6.3 4.8 5 1 1 6 6 6 0 Domain of unknown function (DUF5082) Prominin PF05478.11 CDO77962.1 - 5.4 4.9 20.7 0.8 7.6 1.4 2.9 1 1 1 3 3 3 0 Prominin BLOC1_2 PF10046.9 CDO77962.1 - 9.1 6.7 22.2 14 6.0 3.9 5.1 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 CDO77962.1 - 9.7 6.0 17.2 0.87 9.4 0.6 3.4 4 1 0 4 4 4 0 Protein of unknown function (DUF724) Ribosomal_L44 PF00935.19 CDO77963.1 - 5.3e-37 126.2 11.9 8.4e-37 125.5 11.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 CDO77963.1 - 0.012 15.9 0.3 0.021 15.1 0.3 1.4 1 0 0 1 1 1 0 Cathelicidin DUF5542 PF17696.1 CDO77964.1 - 2.6 8.2 7.4 4.8 7.4 3.9 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5542) RP-C_C PF11800.8 CDO77964.1 - 4 7.5 19.7 5.3 7.1 8.3 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Integrase_H2C2 PF17921.1 CDO77965.1 - 3.4e-18 65.5 0.1 9.9e-18 64.0 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO77965.1 - 1.2e-14 54.5 0.0 2.3e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO77965.1 - 2.7e-07 30.4 0.1 5.5e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CDO77965.1 - 5.1e-07 29.8 0.1 1e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger DUF4939 PF16297.5 CDO77967.1 - 0.0036 17.2 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) gag-asp_proteas PF13975.6 CDO77969.1 - 0.00031 21.3 0.0 0.0006 20.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO77969.1 - 0.0043 17.7 0.0 0.0085 16.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CDO77969.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH_2 PF17919.1 CDO77970.1 - 1.4e-12 47.5 0.0 2.5e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO77970.1 - 4.5e-10 39.7 0.0 8.2e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CDO77970.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain rve PF00665.26 CDO77971.1 - 2.1e-05 24.7 0.0 3.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CDO77972.1 - 4.3e-32 111.4 0.1 6.3e-32 110.9 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CDO77972.1 - 6.8e-20 71.0 0.0 1.3e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO77972.1 - 5.5e-08 33.1 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4326 PF14216.6 CDO77972.1 - 0.062 14.0 0.0 19 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) MATalpha_HMGbox PF04769.12 CDO77972.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box CDH1_2_SANT_HL1 PF18375.1 CDO77972.1 - 0.16 12.7 0.0 0.48 11.1 0.0 1.8 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 Retrotrans_gag PF03732.17 CDO77973.1 - 0.008 16.4 0.3 0.015 15.6 0.3 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Plavaka PF18759.1 CDO77975.1 - 2.5e-26 92.7 0.0 4.3e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Pinin_SDK_memA PF04696.13 CDO77975.1 - 0.42 10.7 7.0 1 9.4 7.0 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region RT_RNaseH_2 PF17919.1 CDO77977.1 - 1.4e-05 25.0 0.0 3.7e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Transposase_21 PF02992.14 CDO77978.1 - 1.1e-10 41.1 0.0 1e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 CDO77978.1 - 0.017 14.8 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) RVT_2 PF07727.14 CDO77980.1 - 8e-23 81.3 0.0 1.1e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CDO77982.1 - 3.1e-12 46.4 0.1 4.5e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type IL34 PF15036.6 CDO77983.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Interleukin 34 Toprim_3 PF13362.6 CDO77985.1 - 0.0034 17.7 0.1 0.0071 16.7 0.1 1.5 1 0 0 1 1 1 1 Toprim domain FYVE PF01363.21 CDO77985.1 - 0.019 15.1 0.4 0.044 13.9 0.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger Retrotran_gag_2 PF14223.6 CDO77987.1 - 1.5e-08 34.4 1.5 2e-08 34.0 0.3 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CDO77987.1 - 2.2e-08 33.6 1.6 2.9e-08 33.2 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) NFACT-R_1 PF05670.13 CDO77987.1 - 0.059 14.0 0.0 0.098 13.3 0.0 1.4 1 1 0 1 1 1 0 NFACT protein RNA binding domain Retrotran_gag_3 PF14244.6 CDO77987.1 - 0.092 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NAAA-beta PF15508.6 CDO77987.1 - 0.13 12.5 0.2 0.9 9.9 0.1 2.3 2 1 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Retrotrans_gag PF03732.17 CDO77988.1 - 6.6e-12 45.5 0.1 2e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO77988.1 - 4.5e-08 33.0 0.0 7.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) MFS_1 PF07690.16 CDO77989.1 - 1.7e-37 129.2 58.1 1.3e-36 126.2 58.1 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO77989.1 - 1.6e-25 89.6 21.3 2.1e-25 89.2 21.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CDO77989.1 - 1.1e-13 50.8 11.1 1.1e-13 50.8 11.1 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 CDO77989.1 - 0.78 7.9 10.8 0.62 8.3 2.1 2.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DDE_3 PF13358.6 CDO77990.1 - 4.2e-12 46.1 0.8 5.3e-12 45.7 0.8 1.2 1 1 0 1 1 1 1 DDE superfamily endonuclease SecY PF00344.20 CDO77991.1 - 2.9e-24 85.9 0.9 3.3e-24 85.7 0.9 1.0 1 0 0 1 1 1 1 SecY translocase DUF4235 PF14019.6 CDO77991.1 - 0.02 15.0 0.4 0.59 10.3 1.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4235) Methyltransf_15 PF09445.10 CDO77992.1 - 2.5e-37 128.0 0.0 2.4e-35 121.5 0.0 2.1 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 CDO77992.1 - 1e-07 32.6 0.0 2.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CDO77992.1 - 1.5e-05 24.9 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 CDO77992.1 - 2.8e-05 24.0 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CDO77992.1 - 3.5e-05 23.5 0.0 9.2e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 CDO77992.1 - 0.00039 21.0 0.0 0.00087 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CDO77992.1 - 0.0047 16.0 0.0 0.0066 15.5 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.7 CDO77992.1 - 0.0093 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CDO77992.1 - 0.015 15.0 0.1 0.12 12.0 0.1 2.2 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 CDO77992.1 - 0.019 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 CDO77992.1 - 0.057 12.9 0.1 0.14 11.6 0.1 1.7 1 1 0 1 1 1 0 RRNA methyltransferase AviRa KDZ PF18758.1 CDO77993.1 - 5e-57 193.1 0.1 6e-56 189.5 0.0 2.7 2 1 1 3 3 3 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 CDO77993.1 - 0.00025 21.2 0.1 0.0006 19.9 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases TetR_C_15 PF17918.1 CDO77996.1 - 0.11 13.2 0.9 0.26 12.1 0.3 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain rve PF00665.26 CDO77997.1 - 6.8e-08 32.7 0.0 2.3e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 CDO77997.1 - 0.01 16.1 0.0 0.039 14.2 0.0 1.8 2 0 0 2 2 2 1 DDE domain Integrase_H2C2 PF17921.1 CDO77998.1 - 5.4e-17 61.6 3.2 1.3e-16 60.5 3.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 CDO77998.1 - 9.8e-10 38.4 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO77998.1 - 3.5e-07 30.5 0.0 6.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDO78000.1 - 0.00022 21.7 0.0 0.00047 20.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 CDO78000.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease DDE_3 PF13358.6 CDO78003.1 - 3e-10 40.0 0.0 5.8e-10 39.1 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease RRM_1 PF00076.22 CDO78004.1 - 5.4e-22 77.4 0.0 8.1e-12 44.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Enterotoxin_a PF01375.17 CDO78004.1 - 0.001 18.8 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain RRM_7 PF16367.5 CDO78004.1 - 0.031 14.4 0.0 0.91 9.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif DUF3433 PF11915.8 CDO78006.1 - 1.3e-10 41.6 5.4 1.7e-10 41.2 0.8 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3433) MutS_V PF00488.21 CDO78007.1 - 5.2e-84 281.0 0.1 9.4e-84 280.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CDO78007.1 - 3.2e-35 122.1 0.8 7e-35 121.0 0.8 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 CDO78007.1 - 3e-17 62.8 0.5 9.5e-17 61.1 0.1 2.2 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 CDO78007.1 - 3.4e-16 59.8 0.0 1.6e-14 54.3 0.0 2.8 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 CDO78007.1 - 3.7e-09 36.8 0.0 8.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 CDO78007.1 - 0.13 11.9 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain FadA PF09403.10 CDO78007.1 - 0.28 11.7 1.7 4.6 7.8 0.0 3.1 3 0 0 3 3 3 0 Adhesion protein FadA Tup_N PF08581.10 CDO78007.1 - 5.5 7.4 6.1 1.7 9.0 0.5 2.9 3 0 0 3 3 3 0 Tup N-terminal Pmp3 PF01679.17 CDO78008.1 - 3.5e-24 84.7 11.6 4.6e-24 84.4 11.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.8 CDO78008.1 - 0.049 13.7 1.2 0.069 13.2 1.2 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DDE_3 PF13358.6 CDO78009.1 - 2.2e-25 89.1 0.1 5.8e-25 87.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.6 CDO78009.1 - 1.7e-06 28.5 1.2 3.2e-06 27.7 0.4 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 CDO78009.1 - 4.3e-05 23.7 0.0 9.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.6 CDO78009.1 - 0.0002 20.9 0.2 0.0006 19.4 0.2 1.8 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.26 CDO78009.1 - 0.0062 16.7 0.0 0.029 14.5 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain PLU-1 PF08429.11 CDO78009.1 - 0.14 11.3 0.0 7.7 5.6 0.0 2.1 2 0 0 2 2 2 0 PLU-1-like protein AP3D1 PF06375.11 CDO78010.1 - 0.0062 16.8 2.5 0.015 15.5 2.5 1.7 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 HIP1_clath_bdg PF16515.5 CDO78011.1 - 0.027 15.1 4.2 0.058 14.0 4.2 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF948 PF06103.11 CDO78011.1 - 0.044 14.0 0.3 0.12 12.7 0.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) THOC7 PF05615.13 CDO78011.1 - 0.061 13.6 1.6 0.11 12.8 1.6 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 Serine_rich PF08824.10 CDO78011.1 - 0.087 12.8 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF1664 PF07889.12 CDO78011.1 - 0.14 12.2 1.7 0.24 11.4 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CLZ PF16526.5 CDO78011.1 - 0.59 10.5 3.2 8.6 6.8 1.7 2.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NolB PF17398.2 CDO78011.1 - 4.8 7.6 8.5 8.3 6.8 0.3 3.0 2 1 1 3 3 3 0 Nodulation protein NolB kleA_kleC PF17383.2 CDO78011.1 - 7.9 6.9 8.3 33 4.9 2.2 3.1 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A Pkinase_fungal PF17667.1 CDO78012.1 - 1.5e-45 155.7 0.0 1.7e-24 86.4 0.0 3.2 1 1 1 2 2 2 2 Fungal protein kinase Pkinase_fungal PF17667.1 CDO78013.1 - 3.7e-44 151.1 0.0 2.6e-23 82.5 0.0 2.7 1 1 1 2 2 2 2 Fungal protein kinase Pkinase_Tyr PF07714.17 CDO78013.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 CDO78013.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_fungal PF17667.1 CDO78014.1 - 1.3e-40 139.4 0.0 9.2e-21 74.1 0.0 2.8 1 1 1 2 2 2 2 Fungal protein kinase Arrestin_N PF00339.29 CDO78015.1 - 1.5e-12 47.8 0.0 2.2e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CDO78015.1 - 6e-10 39.7 0.0 1.9e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain FMN_dh PF01070.18 CDO78016.1 - 1.8e-118 395.6 0.0 2.1e-118 395.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CDO78016.1 - 5.5e-22 77.7 0.0 1.4e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CDO78016.1 - 3.2e-05 23.2 0.0 5.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CDO78016.1 - 0.00065 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CDO78017.1 - 4.1e-118 394.4 0.0 5e-118 394.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CDO78017.1 - 2.5e-21 75.6 0.0 5.1e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 CDO78017.1 - 4e-06 26.1 0.0 8e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CDO78017.1 - 6.1e-05 22.3 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 CDO78017.1 - 0.02 14.2 0.1 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 CDO78017.1 - 0.18 11.0 0.1 7.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase PEP_mutase PF13714.6 CDO78018.1 - 1.6e-43 148.9 3.2 2.1e-43 148.5 3.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 CDO78018.1 - 3.4e-17 62.1 0.6 4.6e-17 61.7 0.6 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PEP_hydrolase PF09370.10 CDO78018.1 - 0.046 12.9 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Pkinase_fungal PF17667.1 CDO78019.1 - 2.3e-41 141.9 0.0 1.6e-20 73.2 0.0 3.6 2 1 1 3 3 3 2 Fungal protein kinase TMEM70 PF06979.12 CDO78020.1 - 6.1e-06 26.7 0.4 8.4e-06 26.2 0.4 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex DUF3537 PF12056.8 CDO78020.1 - 0.068 12.0 0.0 0.091 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Hexapep PF00132.24 CDO78021.1 - 1.1e-11 44.0 18.0 2.3e-07 30.2 2.2 4.6 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CDO78021.1 - 9.1e-07 28.5 11.9 0.00072 19.3 0.6 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CDO78021.1 - 0.00017 20.7 0.0 0.00024 20.1 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase TrkH PF02386.16 CDO78022.1 - 9.8e-108 360.7 10.6 5.5e-106 355.0 3.9 2.1 2 0 0 2 2 2 2 Cation transport protein Hum_adeno_E3A PF05393.11 CDO78022.1 - 0.11 12.5 0.2 0.38 10.8 0.2 1.9 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Keratin_B2_2 PF13885.6 CDO78022.1 - 0.13 12.3 0.3 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Pkinase_fungal PF17667.1 CDO78023.1 - 5.5e-44 150.6 0.0 1.1e-25 90.3 0.0 2.3 1 1 1 2 2 2 2 Fungal protein kinase Pkinase_fungal PF17667.1 CDO78024.1 - 5.8e-31 107.7 0.0 1.1e-18 67.3 0.0 3.0 1 1 1 2 2 2 2 Fungal protein kinase LCM PF04072.14 CDO78025.1 - 7.2e-22 78.2 0.0 1.4e-21 77.3 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DUF4827 PF16109.5 CDO78025.1 - 0.2 11.6 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4827) Tim17 PF02466.19 CDO78026.1 - 2.7e-34 117.9 5.5 3.4e-34 117.6 5.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ABA_WDS PF02496.16 CDO78026.1 - 0.028 14.9 0.4 6.9 7.2 0.0 2.5 2 0 0 2 2 2 0 ABA/WDS induced protein DUF543 PF04418.12 CDO78026.1 - 0.14 12.1 1.7 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) H_lectin PF09458.10 CDO78028.1 - 1.9 8.8 5.1 1.6 9.0 0.3 2.5 2 0 0 2 2 2 0 H-type lectin domain zf-C2H2 PF00096.26 CDO78029.1 - 0.21 12.1 6.7 0.15 12.6 3.9 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CDO78029.1 - 1.8 9.6 5.0 5.4 8.1 5.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Lipase_2 PF01674.18 CDO78030.1 - 0.15 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) YdiH PF15930.5 CDO78030.1 - 0.2 11.9 0.1 0.4 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function RT_RNaseH_2 PF17919.1 CDO78031.1 - 1.8e-23 82.5 0.0 2.7e-10 40.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CDO78031.1 - 1.7e-22 79.7 0.0 3.7e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO78031.1 - 2.4e-20 73.0 0.0 4.2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CDO78031.1 - 2.3e-05 24.9 0.0 6.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDO78031.1 - 5.2e-05 23.7 0.5 0.00015 22.2 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease FXMR_C2 PF16098.5 CDO78031.1 - 0.049 14.1 1.6 0.12 12.8 1.6 1.6 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 RVP PF00077.20 CDO78031.1 - 0.12 12.7 0.1 0.63 10.4 0.1 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease RVT_1 PF00078.27 CDO78032.1 - 2.6e-23 82.7 0.0 6.7e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 CDO78032.1 - 2.6e-10 40.2 0.8 8.6e-10 38.5 0.1 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 CDO78032.1 - 9.9e-07 29.0 0.0 3.1e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 CDO78032.1 - 5.3e-06 27.0 0.0 1.3e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 CDO78032.1 - 7.3e-05 22.4 2.8 0.0001 21.9 0.4 2.6 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family Fez1 PF06818.15 CDO78033.1 - 0.23 11.9 1.4 0.34 11.4 1.4 1.2 1 0 0 1 1 1 0 Fez1 Prefoldin_2 PF01920.20 CDO78033.1 - 0.24 11.4 0.9 0.64 10.0 0.2 1.9 2 0 0 2 2 2 0 Prefoldin subunit CLZ PF16526.5 CDO78033.1 - 0.33 11.3 3.1 0.98 9.8 1.0 2.5 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-CCHC PF00098.23 CDO78033.1 - 0.9 9.7 2.4 2.2 8.5 2.4 1.7 1 1 0 1 1 1 0 Zinc knuckle DDE_3 PF13358.6 CDO78034.1 - 1.6e-09 37.7 0.1 7.2e-05 22.6 0.1 2.6 2 0 0 2 2 2 2 DDE superfamily endonuclease Asp PF00026.23 CDO78035.1 - 3.9e-51 174.3 5.7 4.6e-51 174.1 5.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CDO78035.1 - 4.5e-13 49.8 3.1 1.7e-11 44.6 3.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CDO78035.1 - 0.13 12.9 0.1 0.47 11.1 0.1 1.9 1 1 0 1 1 1 0 Aspartyl protease Exo_endo_phos_2 PF14529.6 CDO78037.1 - 9.6e-06 25.4 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 CDO78037.1 - 8.8e-05 22.1 0.7 0.0002 20.9 0.7 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thiamine_BP PF01910.17 CDO78038.1 - 0.0074 16.2 0.7 0.015 15.2 0.1 1.8 2 0 0 2 2 2 1 Thiamine-binding protein MscS_porin PF12795.7 CDO78038.1 - 0.082 12.5 3.4 0.14 11.6 3.4 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF2203 PF09969.9 CDO78038.1 - 0.1 13.3 1.1 0.23 12.2 0.7 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FTR_C PF02741.15 CDO78038.1 - 0.16 12.0 0.1 0.37 10.8 0.1 1.6 1 0 0 1 1 1 0 FTR, proximal lobe Syntaxin-6_N PF09177.11 CDO78038.1 - 0.19 12.3 0.9 4 8.1 0.3 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal adh_short PF00106.25 CDO78039.1 - 3.3e-24 85.4 0.0 4.2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CDO78039.1 - 8.1e-12 45.2 0.0 1.1e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO78039.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 CDO78039.1 - 0.0023 17.9 0.1 0.0045 16.9 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus Epimerase PF01370.21 CDO78039.1 - 0.0039 16.7 0.0 0.0068 15.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.23 CDO78039.1 - 0.052 13.5 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.6 CDO78039.1 - 0.11 12.4 0.2 0.54 10.1 0.2 2.0 1 1 0 1 1 1 0 NAD(P)H-binding Pyr_redox PF00070.27 CDO78039.1 - 0.11 13.1 0.1 0.21 12.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DFP PF04127.15 CDO78039.1 - 0.13 12.1 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Aminotran_1_2 PF00155.21 CDO78040.1 - 4.8e-34 118.1 0.0 1.5e-33 116.5 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CDO78040.1 - 0.0026 16.4 0.0 0.0042 15.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 CDO78040.1 - 0.0061 15.3 0.0 0.0083 14.9 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 CDO78040.1 - 0.015 14.3 0.0 0.37 9.7 0.0 2.5 3 0 0 3 3 3 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 CDO78040.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Rubrerythrin PF02915.17 CDO78041.1 - 0.00083 19.8 12.1 0.0026 18.2 1.2 2.0 2 1 1 3 3 3 2 Rubrerythrin BAR_3 PF16746.5 CDO78041.1 - 0.12 12.1 5.1 0.23 11.1 5.1 1.4 1 0 0 1 1 1 0 BAR domain of APPL family SARAF PF06682.12 CDO78042.1 - 9.3e-72 242.5 0.0 1.1e-71 242.3 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis adh_short PF00106.25 CDO78043.1 - 1.6e-21 76.6 0.0 1.4e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CDO78043.1 - 8.3e-11 41.9 0.0 9.2e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CDO78043.1 - 1.7e-05 24.8 0.0 6.6e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 CDO78043.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 CDO78043.1 - 0.032 13.6 0.0 0.064 12.6 0.0 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) EphA2_TM PF14575.6 CDO78044.1 - 0.096 13.6 0.0 0.28 12.1 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CDO78044.1 - 0.63 9.9 2.4 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family HNH_2 PF13391.6 CDO78046.1 - 3.7e-06 27.0 0.0 8e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 HNH endonuclease EF_assoc_2 PF08356.12 CDO78046.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 EF hand associated DUF2621 PF11084.8 CDO78047.1 - 0.23 11.4 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Plavaka PF18759.1 CDO78049.1 - 7.3e-116 386.9 0.0 1.1e-115 386.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DDE_1 PF03184.19 CDO78051.1 - 0.00027 20.6 0.0 0.00092 18.9 0.0 1.9 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CDO78051.1 - 0.0037 17.2 0.1 0.01 15.9 0.1 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Abhydrolase_6 PF12697.7 CDO78052.1 - 3.1e-18 67.2 4.2 4.4e-18 66.7 4.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CDO78052.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 CDO78052.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FA_desaturase PF00487.24 CDO78053.1 - 1.1e-25 91.0 19.1 1.1e-25 91.0 19.1 1.5 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 CDO78053.1 - 0.0074 16.5 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) CBM_1 PF00734.18 CDO78054.1 - 2.3e-11 43.5 14.4 6e-11 42.1 14.4 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Abhydrolase_1 PF00561.20 CDO78054.1 - 5.6e-11 42.6 0.9 1.7e-10 41.0 0.5 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO78054.1 - 1.9e-05 25.4 2.3 4.3e-05 24.2 2.3 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CDO78054.1 - 0.18 11.0 0.0 0.45 9.7 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Na_H_Exchanger PF00999.21 CDO78056.1 - 3.4e-21 75.5 35.7 2.9e-11 42.8 15.4 4.1 4 0 0 4 4 4 4 Sodium/hydrogen exchanger family zf-RRN7 PF11781.8 CDO78057.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Peptidase_S10 PF00450.22 CDO78058.1 - 2.2e-96 323.8 2.5 2.6e-96 323.6 2.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Nucleolin_bd PF16725.5 CDO78058.1 - 0.063 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Nucleolin binding domain GDI PF00996.18 CDO78059.1 - 1.2e-41 142.7 0.0 3.3e-40 137.9 0.0 2.2 2 1 0 2 2 2 1 GDP dissociation inhibitor S36_mt PF10937.8 CDO78059.1 - 9.6e-11 43.3 1.7 4.9e-10 41.0 1.7 2.3 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial NAD_binding_8 PF13450.6 CDO78059.1 - 8.5e-05 22.7 0.1 0.00025 21.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CDO78059.1 - 0.2 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase RRM_1 PF00076.22 CDO78060.1 - 3.9e-44 148.3 0.0 1.3e-22 79.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CDO78060.1 - 2.2e-09 37.3 0.1 7.5e-05 22.8 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CDO78060.1 - 0.00027 20.5 0.0 0.0064 16.1 0.0 2.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CDO78060.1 - 0.0099 15.9 0.1 0.69 10.0 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CDO78060.1 - 0.017 15.0 0.0 5.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF1866 PF08952.11 CDO78060.1 - 0.057 13.3 0.0 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Proteasome PF00227.26 CDO78061.1 - 9e-47 159.0 0.4 4.5e-46 156.8 0.4 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CDO78061.1 - 2.9e-14 52.4 0.2 5.4e-14 51.5 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flagellin_N PF00669.20 CDO78061.1 - 0.067 13.3 0.4 0.13 12.4 0.4 1.4 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region RNA_pol_Rpb1_1 PF04997.12 CDO78062.1 - 5.4e-86 288.8 0.0 8.2e-86 288.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CDO78062.1 - 6.5e-85 284.8 0.2 9.6e-85 284.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CDO78062.1 - 2.9e-64 216.3 0.0 6.8e-64 215.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CDO78062.1 - 3.6e-38 131.0 0.0 4.1e-37 127.6 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CDO78062.1 - 9.8e-30 102.7 0.0 2.2e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF2786 PF10979.8 CDO78062.1 - 0.0066 16.3 0.3 0.015 15.2 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) DUF1317 PF07026.11 CDO78062.1 - 0.16 11.8 0.0 0.5 10.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) DUF4939 PF16297.5 CDO78063.1 - 6.2e-09 35.7 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 CDO78063.1 - 0.0022 18.2 0.0 0.0067 16.7 0.0 1.9 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 CDO78063.1 - 0.29 11.3 0.3 0.45 10.7 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle FAM199X PF15814.5 CDO78063.1 - 0.73 8.8 7.1 1.1 8.3 7.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X SOG2 PF10428.9 CDO78063.1 - 6.7 5.8 23.5 1.8 7.7 8.1 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Pkinase_fungal PF17667.1 CDO78064.1 - 5.9e-36 124.1 0.0 1.4e-35 122.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 CDO78064.1 - 0.00024 20.6 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO78064.1 - 0.032 13.5 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Retrotran_gag_2 PF14223.6 CDO78066.1 - 3.5e-10 39.7 0.0 5.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO78066.1 - 0.022 14.8 5.3 0.034 14.2 5.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 CDO78066.1 - 0.045 13.7 2.3 0.079 12.9 2.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 CDO78067.1 - 2.8e-13 50.0 0.0 6.4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO78067.1 - 8.2e-10 38.6 0.0 2e-09 37.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) Retrotran_gag_2 PF14223.6 CDO78067.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_6 PF15288.6 CDO78067.1 - 0.47 10.3 2.5 1.5 8.7 2.5 1.9 1 0 0 1 1 1 0 Zinc knuckle RAP1 PF07218.11 CDO78067.1 - 0.48 8.7 5.2 0.62 8.3 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-RVT PF13966.6 CDO78068.1 - 7.8e-07 29.7 0.0 1.1e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase MINDY_DUB PF04424.13 CDO78070.1 - 0.038 14.0 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 MINDY deubiquitinase ABATE PF07336.11 CDO78070.1 - 0.056 14.1 0.6 1 10.0 0.1 2.4 2 0 0 2 2 2 0 Putative stress-induced transcription regulator ABC_tran PF00005.27 CDO78071.1 - 5.2e-25 88.5 0.0 9.3e-15 55.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CDO78071.1 - 1.5e-07 31.6 0.1 0.0042 16.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CDO78071.1 - 6.9e-05 23.0 0.0 0.17 12.2 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CDO78071.1 - 0.0032 17.2 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CDO78071.1 - 0.0073 16.6 0.4 0.19 12.0 0.0 2.8 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CDO78071.1 - 0.085 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 CDO78071.1 - 0.1 13.1 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 CDO78071.1 - 0.14 11.5 0.0 31 3.9 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Ribosomal_L23eN PF03939.13 CDO78072.1 - 3.3e-25 88.0 10.3 7e-25 87.0 10.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CDO78072.1 - 1.8e-17 63.5 2.3 9.5e-17 61.2 2.3 2.1 1 1 0 1 1 1 1 Ribosomal protein L23 DUF5451 PF17532.2 CDO78072.1 - 0.0017 18.6 0.8 0.0023 18.2 0.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5451) Peptidase_M28 PF04389.17 CDO78073.1 - 1.1e-33 116.6 0.0 1.7e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CDO78073.1 - 0.00014 21.7 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 DUF5357 PF17310.2 CDO78073.1 - 0.083 11.4 0.2 0.15 10.6 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5357) DDE_3 PF13358.6 CDO78075.1 - 1.4e-10 41.1 0.5 2.7e-10 40.2 0.5 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_21 PF02992.14 CDO78075.1 - 8.8e-10 38.2 0.0 1.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 CDO78075.1 - 0.015 14.9 0.1 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) GST_N_3 PF13417.6 CDO78078.1 - 1.9e-17 63.4 0.0 3.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO78078.1 - 1.5e-16 60.5 0.0 2.6e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO78078.1 - 2.2e-09 37.5 0.3 7.1e-09 35.9 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO78078.1 - 4.2e-07 29.9 0.0 7.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CDO78078.1 - 2.5e-06 27.6 0.1 4.4e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 CDO78078.1 - 0.00029 21.4 0.0 0.00042 20.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO78078.1 - 0.00064 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain IR1-M PF12185.8 CDO78078.1 - 0.083 12.8 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain Retrotran_gag_2 PF14223.6 CDO78080.1 - 3.7e-17 62.3 0.0 7.3e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CDO78080.1 - 8.6e-08 31.7 0.3 1.9e-07 30.5 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) DUF4687 PF15747.5 CDO78080.1 - 0.026 15.0 1.2 0.057 13.9 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) zf-MYND PF01753.18 CDO78081.1 - 1.5e-09 37.7 11.9 3.6e-09 36.6 11.9 1.7 1 0 0 1 1 1 1 MYND finger Desulfoferrod_N PF06397.12 CDO78081.1 - 0.27 10.9 2.5 0.8 9.4 2.5 1.8 1 1 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain TAtT PF16811.5 CDO78082.1 - 0.061 12.6 0.4 6.2 6.0 0.1 2.2 1 1 1 2 2 2 0 TRAP transporter T-component Ribosomal_L37 PF08561.10 CDO78083.1 - 3.3 8.2 9.3 6.5 7.3 9.3 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Adenylsucc_synt PF00709.21 CDO78084.1 - 3.9e-176 586.1 0.0 4.4e-176 585.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase PCI PF01399.27 CDO78085.1 - 3.2e-17 63.0 0.3 3.8e-17 62.7 0.3 1.0 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 CDO78085.1 - 0.00089 19.1 0.3 0.017 15.1 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DDRGK PF09756.9 CDO78085.1 - 0.12 12.0 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 DDRGK domain COG6 PF06419.11 CDO78087.1 - 0.24 9.6 0.3 0.34 9.1 0.3 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF4218 PF13960.6 CDO78088.1 - 0.0036 16.9 0.0 0.0076 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Glyco_hydro_18 PF00704.28 CDO78089.1 - 1.8e-16 60.8 0.8 2.3e-16 60.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 CDO78090.1 - 9.8e-09 35.4 0.3 2.2e-08 34.2 0.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DDE_Tnp_4 PF13359.6 CDO78092.1 - 5e-23 81.5 0.0 7.4e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO78092.1 - 2.4e-06 27.4 0.0 1.8e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO78092.1 - 1.7e-05 24.6 0.0 0.00013 21.6 0.1 1.9 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 CDO78092.1 - 0.00016 22.0 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain UVR PF02151.19 CDO78092.1 - 0.35 10.7 2.3 0.73 9.7 2.3 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif Myb_DNA-bind_3 PF12776.7 CDO78093.1 - 2.7e-09 37.9 0.1 4e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO78093.1 - 5.9e-09 36.2 0.2 1e-08 35.5 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CDO78093.1 - 0.00084 19.4 0.1 0.0031 17.6 0.1 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myc_N PF01056.18 CDO78093.1 - 0.0036 17.3 1.3 0.0054 16.7 1.3 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Tub_N PF16322.5 CDO78093.1 - 0.0047 17.4 1.7 0.0085 16.5 1.7 1.4 1 0 0 1 1 1 1 Tubby N-terminal Myb_DNA-binding PF00249.31 CDO78093.1 - 0.0084 16.3 0.3 0.017 15.3 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain LAT PF15234.6 CDO78093.1 - 0.025 14.3 1.8 0.039 13.7 1.8 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells TAP42 PF04177.12 CDO78093.1 - 0.036 13.2 1.0 0.054 12.6 1.0 1.3 1 0 0 1 1 1 0 TAP42-like family TAL_effector PF03377.13 CDO78093.1 - 0.06 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 TAL effector repeat Myb_DNA-bind_6 PF13921.6 CDO78093.1 - 0.1 12.9 0.2 0.22 11.8 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain RRN3 PF05327.11 CDO78093.1 - 0.14 10.7 2.2 0.18 10.3 2.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 CDO78093.1 - 0.42 8.7 4.5 0.6 8.1 4.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 CDO78093.1 - 2.4 8.6 11.8 4.5 7.7 11.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 CDO78093.1 - 7.9 5.7 8.5 12 5.1 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein KinB_sensor PF16767.5 CDO78094.1 - 0.088 13.3 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Plavaka PF18759.1 CDO78095.1 - 2.2e-25 89.6 0.0 3.7e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase HET PF06985.11 CDO78096.1 - 1.5e-13 51.3 0.3 3.5e-10 40.4 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) API5 PF05918.11 CDO78097.1 - 1.2e-21 77.2 0.0 2.9e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) NmrA PF05368.13 CDO78099.1 - 8e-10 38.7 0.1 1.1e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CDO78099.1 - 2.3e-07 30.9 0.1 2.6e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CDO78099.1 - 0.0017 18.8 0.0 0.0063 16.9 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CDO78099.1 - 0.0062 16.8 0.1 0.0095 16.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 CDO78099.1 - 0.058 12.5 0.1 0.14 11.3 0.1 1.6 1 1 1 2 2 2 0 Male sterility protein Epimerase PF01370.21 CDO78100.1 - 1.2e-14 54.4 0.0 9.5e-14 51.4 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CDO78100.1 - 3.2e-12 46.2 0.0 3e-11 43.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 CDO78100.1 - 5.5e-12 45.3 0.0 8.8e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CDO78100.1 - 8.6e-10 38.5 0.0 2.3e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CDO78100.1 - 1.5e-06 28.2 0.0 8.1e-06 25.9 0.0 2.1 2 1 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CDO78100.1 - 7.7e-06 25.2 0.1 1.6e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CDO78100.1 - 0.00046 19.8 0.1 0.0022 17.6 0.1 2.0 1 1 1 2 2 2 1 NmrA-like family KR PF08659.10 CDO78100.1 - 0.00077 19.4 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 CDO78100.1 - 0.0022 17.5 0.0 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase AROS PF15684.5 CDO78100.1 - 0.25 11.9 0.0 0.4 11.3 0.0 1.3 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Dynamin_M PF01031.20 CDO78101.1 - 1.3e-31 109.9 0.0 2.9e-31 108.8 0.0 1.5 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CDO78101.1 - 6.7e-26 91.3 0.0 1.8e-25 90.0 0.0 1.8 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 CDO78101.1 - 8.1e-10 38.7 0.6 3.8e-09 36.6 0.4 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CDO78101.1 - 3.7e-06 27.0 0.9 0.042 13.9 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 CDO78101.1 - 0.00056 20.3 1.3 0.0028 18.0 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 CDO78101.1 - 0.005 17.1 0.2 0.022 15.0 0.2 2.2 1 0 0 1 1 1 1 AAA domain Retrotrans_gag PF03732.17 CDO78103.1 - 5.1e-09 36.3 0.3 7.7e-09 35.7 0.3 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 CDO78103.1 - 0.0042 17.1 2.9 0.0063 16.5 2.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CDO78103.1 - 0.056 13.2 1.1 0.093 12.5 1.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 CDO78103.1 - 0.16 11.8 1.6 0.26 11.1 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.14 CDO78104.1 - 5.9e-19 68.7 0.0 9.2e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO78104.1 - 0.00045 20.4 0.0 0.00079 19.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 CDO78105.1 - 1.1e-14 54.6 0.0 1.9e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDO78105.1 - 0.07 12.9 0.2 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Retrotran_gag_2 PF14223.6 CDO78107.1 - 1e-15 57.6 0.2 1.8e-15 56.8 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 CDO78107.1 - 2.4e-11 43.9 0.0 5.4e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 CDO78107.1 - 9.8e-05 22.3 2.7 0.00023 21.1 2.7 1.7 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.6 CDO78107.1 - 0.0021 17.9 0.1 0.0043 16.9 0.1 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain FTP PF07504.13 CDO78107.1 - 0.037 13.9 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Retrotrans_gag PF03732.17 CDO78108.1 - 7.5e-13 48.6 0.0 1.9e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO78108.1 - 9e-08 32.0 0.1 2.5e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) SR-25 PF10500.9 CDO78108.1 - 0.92 9.1 13.8 1.7 8.2 13.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GMC_oxred_N PF00732.19 CDO78110.1 - 1.1e-54 185.8 0.0 2.6e-53 181.4 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO78110.1 - 1.8e-33 116.1 0.0 3.9e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CDO78110.1 - 2.2e-05 24.6 0.1 6.1e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CDO78110.1 - 4e-05 23.0 0.2 0.00015 21.1 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 CDO78110.1 - 0.00018 20.7 0.2 0.0003 19.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CDO78110.1 - 0.0026 17.4 3.2 0.0054 16.4 1.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CDO78110.1 - 0.013 14.7 0.7 0.018 14.1 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 CDO78110.1 - 0.025 13.8 0.8 0.38 9.9 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CDO78110.1 - 0.059 13.4 0.3 0.15 12.0 0.3 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 CDO78110.1 - 0.093 13.3 0.3 1.9 9.1 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDO78110.1 - 0.11 11.1 0.1 0.35 9.5 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 CDO78110.1 - 0.23 10.7 0.3 2.9 7.1 0.1 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 CDO78111.1 - 5.4e-24 84.8 32.4 6.7e-24 84.5 32.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_25 PF13649.6 CDO78112.1 - 9.2e-06 26.3 0.0 0.00081 20.1 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain MFS_1 PF07690.16 CDO78114.1 - 1.2e-45 156.0 36.2 3.4e-45 154.5 36.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CDO78114.1 - 1.2e-14 53.7 17.1 1.5e-14 53.4 17.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CDO78114.1 - 2.2e-14 53.2 8.0 2.2e-14 53.2 8.0 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 CDO78114.1 - 0.0009 18.2 4.7 0.0009 18.2 4.7 2.3 2 0 0 2 2 2 1 MFS_1 like family B12D PF06522.11 CDO78114.1 - 0.043 13.6 0.4 0.043 13.6 0.4 2.8 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Claudin_2 PF13903.6 CDO78114.1 - 0.066 13.0 0.2 0.066 13.0 0.2 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction S1FA PF04689.13 CDO78114.1 - 0.7 10.1 0.0 0.7 10.1 0.0 2.4 2 0 0 2 2 2 0 DNA binding protein S1FA ApoO PF09769.9 CDO78114.1 - 1.7 8.7 3.8 34 4.4 0.7 3.1 2 1 1 3 3 3 0 Apolipoprotein O DUF3040 PF11239.8 CDO78114.1 - 1.9 8.8 14.9 0.22 11.8 0.6 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) OATP PF03137.20 CDO78114.1 - 3.9 5.6 12.3 2.3 6.4 1.3 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GMC_oxred_N PF00732.19 CDO78115.1 - 2.4e-50 171.6 0.0 4.5e-50 170.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO78115.1 - 1.2e-29 103.6 0.0 2.1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CDO78115.1 - 5.8e-05 23.2 0.1 0.00037 20.7 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CDO78115.1 - 0.0003 20.0 0.1 0.00047 19.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CDO78115.1 - 0.0018 17.9 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CDO78115.1 - 0.0021 17.3 0.1 0.0043 16.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 CDO78115.1 - 0.007 15.5 0.4 0.014 14.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CDO78115.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CDO78115.1 - 0.027 13.2 0.1 0.043 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Sulfatase PF00884.23 CDO78116.1 - 0.091 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Sulfatase Pns11_12 PF17464.2 CDO78117.1 - 0.11 12.2 0.4 0.19 11.4 0.4 1.3 1 0 0 1 1 1 0 Non-structural protein 11 and 12 OPT PF03169.15 CDO78118.1 - 2.1e-202 674.1 63.2 2.4e-202 673.9 63.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.14 CDO78118.1 - 8.9 6.5 8.9 0.4 10.8 1.0 2.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Zn-ribbon_8 PF09723.10 CDO78122.1 - 0.0052 16.9 3.2 0.0077 16.3 3.2 1.2 1 0 0 1 1 1 1 Zinc ribbon domain zf-FPG_IleRS PF06827.14 CDO78122.1 - 0.0061 16.4 0.9 0.011 15.5 0.9 1.5 1 1 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-RRPl_C4 PF17026.5 CDO78122.1 - 0.0066 16.5 0.3 0.0085 16.2 0.3 1.3 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type zf-UDP PF14569.6 CDO78122.1 - 0.022 14.8 0.8 0.034 14.3 0.8 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger DpnI PF06044.12 CDO78122.1 - 0.026 14.2 0.2 0.026 14.2 0.2 1.1 1 0 0 1 1 1 0 Dam-replacing family HypA PF01155.19 CDO78122.1 - 0.036 14.1 1.1 0.045 13.8 1.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LIM PF00412.22 CDO78122.1 - 0.042 14.1 3.9 0.056 13.7 3.9 1.2 1 0 0 1 1 1 0 LIM domain zinc_ribbon_9 PF14369.6 CDO78122.1 - 0.043 14.1 2.5 0.092 13.0 2.5 1.6 1 1 0 1 1 1 0 zinc-ribbon zf-RING_5 PF14634.6 CDO78122.1 - 0.047 13.7 2.5 0.068 13.1 2.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CDO78122.1 - 0.088 12.7 2.6 0.13 12.1 2.6 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.6 CDO78122.1 - 0.41 10.6 8.3 3.2 7.8 0.3 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Cys_rich_KTR PF14205.6 CDO78122.1 - 2.7 7.9 7.1 62 3.5 7.1 2.2 1 1 0 1 1 1 0 Cysteine-rich KTR MFS_1 PF07690.16 CDO78123.1 - 1.1e-43 149.5 36.7 1.1e-43 149.5 36.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CDO78123.1 - 4.3e-12 45.6 8.9 4.3e-12 45.6 8.9 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CDO78123.1 - 1.5e-06 27.8 12.2 3.6e-06 26.5 7.5 2.4 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Caveolin PF01146.17 CDO78123.1 - 9.7 6.1 7.1 6.8 6.7 0.8 2.7 3 0 0 3 3 3 0 Caveolin FOXP-CC PF16159.5 CDO78124.1 - 0.024 15.3 1.1 3 8.5 0.0 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain PLA2_B PF01735.18 CDO78125.1 - 7.8e-20 70.7 1.0 2.1e-07 29.7 4.4 4.0 3 1 0 3 3 3 3 Lysophospholipase catalytic domain S4 PF01479.25 CDO78126.1 - 2e-10 40.2 0.0 3.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 CDO78126.1 - 0.0038 17.0 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 S4 domain CDC45 PF02724.14 CDO78126.1 - 0.012 14.0 0.1 0.014 13.8 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 CDO78126.1 - 0.45 9.2 5.8 0.039 12.8 1.3 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 GCP_N_terminal PF17681.1 CDO78127.1 - 3.6e-65 220.6 0.0 7.9e-65 219.5 0.0 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CDO78127.1 - 2.7e-59 201.1 5.7 7.4e-59 199.7 1.7 2.1 2 0 0 2 2 2 2 Gamma tubulin complex component C-terminal GST_N_3 PF13417.6 CDO78128.1 - 1.3e-11 44.7 0.0 2.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO78128.1 - 3.2e-08 33.7 0.0 5.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO78128.1 - 2.6e-07 30.9 0.0 5.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CDO78128.1 - 0.00015 22.0 0.3 0.00031 20.9 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin GST_C_2 PF13410.6 CDO78128.1 - 0.00015 21.7 0.1 0.00035 20.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CDO78128.1 - 0.052 13.7 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain rve PF00665.26 CDO78129.1 - 4.8e-10 39.7 0.0 7.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CDO78129.1 - 0.065 13.0 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain SKA1 PF07160.12 CDO78130.1 - 0.061 13.2 5.3 0.04 13.8 2.7 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 U79_P34 PF03064.16 CDO78130.1 - 0.37 10.1 11.9 0.67 9.3 11.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.17 CDO78130.1 - 0.52 9.0 2.4 0.78 8.4 2.4 1.3 1 0 0 1 1 1 0 Presenilin ATP11 PF06644.11 CDO78130.1 - 0.77 9.5 8.1 1.6 8.5 8.1 1.5 1 0 0 1 1 1 0 ATP11 protein DUF1266 PF06889.11 CDO78130.1 - 1.6 8.7 6.0 0.43 10.6 1.5 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1266) DUF4407 PF14362.6 CDO78130.1 - 2.4 7.4 10.0 0.24 10.7 4.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Zn_clus PF00172.18 CDO78130.1 - 2.7 8.2 12.7 0.085 13.0 6.6 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF913 PF06025.12 CDO78130.1 - 9.8 5.0 5.6 8.8 5.2 1.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RT_RNaseH_2 PF17919.1 CDO78131.1 - 6.8e-08 32.5 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 CDO78131.1 - 0.00077 20.0 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CDO78131.1 - 0.0058 17.2 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 CDO78131.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 CDO78131.1 - 0.065 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DivIC PF04977.15 CDO78134.1 - 0.2 11.4 1.1 0.39 10.5 1.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Acetyltransf_10 PF13673.7 CDO78135.1 - 5.5e-05 23.1 0.0 9.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CDO78135.1 - 0.0001 22.6 0.1 0.00026 21.4 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CDO78135.1 - 0.00018 21.7 0.0 0.00036 20.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3410 PF11890.8 CDO78135.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) ATP_bind_1 PF03029.17 CDO78136.1 - 1.7e-73 247.4 0.0 2.1e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CDO78136.1 - 0.14 12.3 0.2 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain GST_N_3 PF13417.6 CDO78137.1 - 8.5e-11 42.1 0.0 1.5e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CDO78137.1 - 5e-08 33.1 0.0 8.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CDO78137.1 - 1.8e-07 31.4 0.1 4.8e-07 30.0 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CDO78137.1 - 0.0002 21.3 0.2 0.00041 20.3 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DDE_3 PF13358.6 CDO78138.1 - 9.1e-17 61.2 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CDO78138.1 - 1.4e-09 38.1 3.7 3.3e-07 30.4 1.3 3.1 3 0 0 3 3 3 1 Transposase HTH_38 PF13936.6 CDO78138.1 - 1.1e-06 28.3 0.1 3.1e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CDO78138.1 - 7.1e-06 25.7 0.2 5.1e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CDO78138.1 - 5.2e-05 23.3 0.0 5.2e-05 23.3 0.0 3.0 4 0 0 4 4 3 1 Helix-turn-helix domain HTH_IclR PF09339.10 CDO78138.1 - 0.00032 20.4 0.0 0.00088 19.0 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.12 CDO78138.1 - 0.00067 19.6 0.1 0.007 16.3 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.6 CDO78138.1 - 0.0013 18.7 1.2 0.0034 17.4 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_r4 PF04545.16 CDO78138.1 - 0.0035 16.8 1.0 0.0053 16.2 0.0 1.8 2 0 0 2 2 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 CDO78138.1 - 0.004 16.5 0.7 0.023 14.1 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 CDO78138.1 - 0.0053 16.6 0.6 0.02 14.7 0.0 2.1 2 1 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 CDO78138.1 - 0.0056 16.6 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_AraC PF00165.23 CDO78138.1 - 0.0088 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family GntR PF00392.21 CDO78138.1 - 0.019 14.6 0.1 0.062 13.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.15 CDO78138.1 - 0.026 14.6 0.1 2.4 8.3 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MarR PF01047.22 CDO78138.1 - 0.039 13.9 0.1 0.13 12.2 0.0 1.9 2 0 0 2 2 1 0 MarR family TilS_C PF11734.8 CDO78138.1 - 0.04 13.3 1.4 0.065 12.7 0.6 1.7 2 0 0 2 2 1 0 TilS substrate C-terminal domain TrmB PF01978.19 CDO78138.1 - 0.13 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.6 CDO78138.1 - 0.16 11.8 2.3 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Phage_NinH PF06322.11 CDO78138.1 - 0.18 11.7 1.9 0.38 10.7 0.1 2.1 2 0 0 2 2 2 0 Phage NinH protein SNF2_N PF00176.23 CDO78139.1 - 4.5e-18 65.1 0.1 1.2e-13 50.5 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 CDO78139.1 - 8.7e-14 51.6 0.2 3.9e-13 49.5 0.0 2.2 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 CDO78139.1 - 5.8e-05 23.4 0.1 0.00019 21.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO78139.1 - 0.0067 16.5 0.2 1.1 9.2 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 CDO78139.1 - 2.1 8.3 8.1 6.8 6.6 8.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-CGNR PF11706.8 CDO78140.1 - 0.023 14.5 1.0 6.9 6.6 0.1 3.6 3 0 0 3 3 3 0 CGNR zinc finger zinc_ribbon_4 PF13717.6 CDO78141.1 - 0.0071 16.2 0.2 0.017 15.0 0.2 1.7 1 0 0 1 1 1 1 zinc-ribbon domain GCV_T PF01571.21 CDO78143.1 - 7.6e-75 251.6 0.0 9.1e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CDO78143.1 - 1.8e-20 72.7 0.1 3.7e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pkinase_fungal PF17667.1 CDO78144.1 - 5.7e-31 107.7 0.0 7.7e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CDO78144.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Transposase_21 PF02992.14 CDO78147.1 - 2.4e-10 40.0 0.0 4.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4817 PF16087.5 CDO78147.1 - 0.012 15.3 0.0 0.037 13.8 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) DUF1258 PF06869.12 CDO78147.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DUF3435 PF11917.8 CDO78148.1 - 0.38 9.6 3.0 0.21 10.5 1.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) Pkinase PF00069.25 CDO78149.1 - 1.6e-06 27.7 0.0 9.5e-06 25.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO78149.1 - 3e-05 23.5 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO78149.1 - 0.051 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO78149.1 - 0.071 11.9 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase LuxC PF05893.14 CDO78150.1 - 0.18 10.8 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Transposase_21 PF02992.14 CDO78151.1 - 2.2e-10 40.1 0.0 4.2e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 CDO78151.1 - 0.08 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Pkinase PF00069.25 CDO78153.1 - 1.5e-06 27.8 0.0 9.9e-06 25.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO78153.1 - 3.2e-05 23.3 0.0 4.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CDO78153.1 - 0.055 13.4 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CDO78153.1 - 0.075 11.8 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase LuxC PF05893.14 CDO78154.1 - 0.18 10.8 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DDE_Tnp_4 PF13359.6 CDO78156.1 - 1.2e-16 60.7 0.0 1.5e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO78156.1 - 2e-05 24.4 0.0 6.1e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO78156.1 - 0.041 13.5 0.0 0.066 12.8 0.0 1.5 1 1 0 1 1 1 0 Plant transposon protein Transposase_21 PF02992.14 CDO78157.1 - 2e-09 37.0 0.0 3.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 RT_RNaseH PF17917.1 CDO78159.1 - 2.4e-33 114.6 0.0 4.2e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO78159.1 - 1.9e-32 111.2 0.0 4.5e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO78159.1 - 2e-29 102.7 0.0 3.1e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CDO78159.1 - 1.7e-17 63.2 0.0 3.6e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CDO78159.1 - 1.5e-12 47.7 0.0 4.1e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 CDO78159.1 - 5.9e-08 32.5 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 CDO78159.1 - 2.4e-05 24.5 0.0 6.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger SNF2_N PF00176.23 CDO78161.1 - 1.7e-15 56.6 0.0 2.8e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDO78161.1 - 1.7e-13 50.8 0.0 2.1e-12 47.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CDO78161.1 - 2.8e-05 23.4 0.0 5.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PH_10 PF15411.6 CDO78162.1 - 2.7e-40 137.4 0.0 4.9e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 CDO78162.1 - 5.5e-26 91.9 0.4 1.1e-25 91.0 0.4 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 CDO78162.1 - 7.3e-17 61.1 0.0 1.5e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.11 CDO78162.1 - 8.9e-13 48.3 0.0 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin DHH PF01368.20 CDO78163.1 - 0.0027 17.9 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 DHH family Glyco_hydro_63 PF03200.16 CDO78166.1 - 1.6e-09 37.1 7.9 6.2e-08 31.8 0.6 4.0 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain Mito_carr PF00153.27 CDO78167.1 - 7e-54 179.7 2.6 8e-24 83.4 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein RhoGAP PF00620.27 CDO78167.1 - 5.2e-32 110.8 0.0 9.1e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Serine_protease PF18405.1 CDO78167.1 - 0.092 11.9 0.2 6.1 5.9 0.0 2.9 3 0 0 3 3 3 0 Gammaproteobacterial serine protease HTH_Tnp_Tc5 PF03221.16 CDO78168.1 - 0.032 14.3 0.0 0.16 12.0 0.0 2.2 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Plavaka PF18759.1 CDO78171.1 - 1.5e-115 385.9 0.0 2.3e-115 385.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase Cu-oxidase_3 PF07732.15 CDO78173.1 - 2.8e-38 130.6 0.3 2.7e-37 127.4 0.4 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CDO78173.1 - 8.1e-38 129.3 3.1 3.9e-34 117.3 0.0 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CDO78173.1 - 1.1e-26 93.8 0.1 1.3e-21 77.4 0.0 3.6 2 1 2 4 4 4 2 Multicopper oxidase RVT_1 PF00078.27 CDO78174.1 - 3.5e-15 56.1 0.0 4.7e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 CDO78174.1 - 5.7e-08 33.1 0.0 1.1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 CDO78174.1 - 0.001 19.7 0.0 0.0022 18.6 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Pro-kuma_activ PF09286.11 CDO78176.1 - 5.5e-40 136.9 0.0 8.2e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Amidohydro_3 PF07969.11 CDO78177.1 - 0.031 13.7 0.1 0.045 13.2 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase family TFIIA PF03153.13 CDO78177.1 - 0.68 9.9 13.4 0.8 9.6 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Calpain_inhib PF00748.19 CDO78178.1 - 2 8.9 0.0 2 8.9 0.0 3.3 3 1 0 3 3 3 0 Calpain inhibitor F-box PF00646.33 CDO78179.1 - 3.1e-08 33.3 0.0 6.2e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO78179.1 - 3.2e-08 33.3 0.0 6.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like FBA_3 PF08268.12 CDO78179.1 - 0.0019 18.2 0.1 2.4 8.1 0.0 2.3 2 0 0 2 2 2 2 F-box associated domain Cullin PF00888.22 CDO78180.1 - 7.7e-210 698.6 0.4 1.3e-209 697.8 0.4 1.4 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CDO78180.1 - 1.7e-28 98.4 5.3 2.2e-28 98.1 2.9 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain Xpo1 PF08389.12 CDO78180.1 - 2.3e-17 63.4 3.6 1.6e-16 60.7 0.0 4.2 5 1 1 6 6 6 1 Exportin 1-like protein HEAT PF02985.22 CDO78180.1 - 0.00047 20.2 2.7 0.021 15.0 0.1 4.7 5 0 0 5 5 5 1 HEAT repeat IBN_N PF03810.19 CDO78180.1 - 0.0024 17.8 0.0 0.04 13.8 0.0 3.2 3 1 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CDO78180.1 - 0.04 14.3 1.1 0.54 10.7 0.0 3.6 4 0 0 4 4 4 0 HEAT repeats Penicillinase_R PF03965.16 CDO78180.1 - 0.13 12.6 0.0 0.5 10.7 0.0 2.1 1 0 0 1 1 1 0 Penicillinase repressor SecA_SW PF07516.13 CDO78180.1 - 0.81 9.7 5.5 1.6 8.7 0.1 3.1 3 0 0 3 3 3 0 SecA Wing and Scaffold domain HEAT_EZ PF13513.6 CDO78180.1 - 5.2 7.7 13.4 4.9 7.8 0.2 6.0 7 0 0 7 7 7 0 HEAT-like repeat DnaJ_C PF01556.18 CDO78181.1 - 1e-29 103.5 0.0 1.6e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CDO78181.1 - 5.9e-26 90.4 4.7 5.9e-26 90.4 4.7 1.9 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CDO78181.1 - 1.1e-14 54.5 16.6 1.8e-14 53.8 16.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CDO78181.1 - 5.7e-06 26.2 7.5 0.0058 16.6 0.9 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CDO78181.1 - 3.3e-05 23.9 4.3 0.13 12.3 1.2 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 CDO78181.1 - 0.0092 16.3 7.6 1 9.8 1.0 3.2 2 1 1 3 3 3 2 Restriction alleviation protein Lar zinc_ribbon_6 PF14599.6 CDO78181.1 - 0.012 15.6 0.5 0.012 15.6 0.5 2.5 2 0 0 2 2 2 0 Zinc-ribbon TackOD1 PF18551.1 CDO78181.1 - 0.92 9.2 6.3 0.56 9.8 0.4 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 CDO78181.1 - 1.2 9.3 9.4 5.5 7.1 9.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.10 CDO78181.1 - 2 8.2 8.9 27 4.6 0.5 3.5 3 0 0 3 3 3 0 A2L zinc ribbon domain zinc_ribbon_9 PF14369.6 CDO78181.1 - 2.9 8.2 12.5 13 6.1 0.0 4.1 3 1 1 4 4 4 0 zinc-ribbon zf-RING_5 PF14634.6 CDO78181.1 - 4.2 7.4 9.0 5.6 7.0 1.9 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_1 PF14446.6 CDO78181.1 - 9.2 6.3 8.4 3.6 7.6 1.0 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 SAP PF02037.27 CDO78184.1 - 0.0087 15.8 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 SAP domain AP1AR PF15745.5 CDO78184.1 - 3.4 7.2 10.3 4.8 6.7 10.3 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF659 PF04937.15 CDO78186.1 - 2.9e-13 50.0 0.0 5.1e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CDO78186.1 - 3.7e-05 23.4 0.0 9.3e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region EHN PF06441.12 CDO78188.1 - 3.7e-35 120.6 0.0 7.6e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CDO78188.1 - 6.8e-11 42.3 0.4 2.6e-10 40.4 0.4 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CDO78188.1 - 0.0049 17.5 6.3 0.0049 17.5 6.3 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Glycos_transf_3 PF00591.21 CDO78189.1 - 2.1e-59 201.2 0.0 2.4e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain RVT_2 PF07727.14 CDO78191.1 - 4e-41 141.3 0.0 6e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CDO78192.1 - 3.7e-23 81.7 0.0 6.4e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 CDO78192.1 - 7e-16 58.5 0.0 2e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CDO78192.1 - 3.4e-10 39.6 0.0 7.2e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 CDO78192.1 - 0.0015 18.2 0.1 0.0048 16.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DUF4219 PF13961.6 CDO78192.1 - 0.15 11.8 1.6 0.43 10.3 1.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC PF00098.23 CDO78192.1 - 0.25 11.5 5.0 0.72 10.0 5.0 1.9 1 1 0 1 1 1 0 Zinc knuckle Pkinase_fungal PF17667.1 CDO78194.1 - 1.8e-47 162.0 0.0 6.6e-47 160.2 0.0 1.9 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO78195.1 - 2.3e-49 168.3 0.0 2.9e-48 164.7 0.0 2.2 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CDO78195.1 - 0.051 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Rer1 PF03248.13 CDO78196.1 - 2.4e-58 196.6 1.6 1e-48 165.3 0.2 2.0 1 1 1 2 2 2 2 Rer1 family Pkinase_fungal PF17667.1 CDO78197.1 - 7.9e-44 150.0 0.0 6.7e-23 81.1 0.0 2.4 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 CDO78197.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 CDO78197.1 - 0.08 12.9 0.6 1.5 8.7 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Steroid_dh PF02544.16 CDO78198.1 - 3.1e-30 105.2 6.2 5.9e-21 75.0 6.9 3.0 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CDO78198.1 - 2e-07 30.8 1.4 4e-06 26.5 1.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 CDO78198.1 - 0.16 12.4 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family zf-CCCH_4 PF18044.1 CDO78199.1 - 6.6e-05 22.6 0.5 6.6e-05 22.6 0.5 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CDO78199.1 - 0.0011 18.9 0.4 0.0011 18.9 0.4 2.8 2 1 0 2 2 2 1 Zinc finger domain TPR_1 PF00515.28 CDO78199.1 - 0.0017 18.1 5.8 0.054 13.3 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH_2 PF14608.6 CDO78199.1 - 0.007 16.8 11.3 0.31 11.6 6.7 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CDO78199.1 - 0.028 14.6 3.7 0.062 13.5 3.7 1.5 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH PF00642.24 CDO78199.1 - 0.029 14.3 0.1 0.029 14.3 0.1 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MIase PF02426.16 CDO78199.1 - 0.1 12.7 1.6 3.5 7.9 0.7 2.6 1 1 0 2 2 2 0 Muconolactone delta-isomerase TPR_17 PF13431.6 CDO78199.1 - 0.17 12.3 0.8 1.3 9.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CDO78199.1 - 0.2 12.0 1.1 1.5 9.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Torus PF16131.5 CDO78199.1 - 1 10.1 7.8 1.9 9.2 0.1 2.6 1 1 1 2 2 2 0 Torus domain TPR_2 PF07719.17 CDO78199.1 - 2.5 8.4 14.8 1.7 9.0 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CDO78199.1 - 3.9 8.2 14.6 0.19 12.4 5.8 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat APH PF01636.23 CDO78201.1 - 2.1e-11 44.2 0.1 2.9e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Plavaka PF18759.1 CDO78202.1 - 2e-116 388.8 0.0 3.7e-116 387.9 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase MFS_1 PF07690.16 CDO78203.1 - 7.3e-32 110.7 50.5 2e-24 86.2 17.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 CDO78203.1 - 4.3e-07 28.7 6.8 2.5e-06 26.2 0.1 2.5 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Beta-APP PF03494.13 CDO78203.1 - 2.7 7.9 6.0 7.4 6.5 0.4 2.5 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) Sugar_tr PF00083.24 CDO78203.1 - 6.2 5.6 33.5 0.032 13.1 12.6 4.1 3 1 2 5 5 5 0 Sugar (and other) transporter Pkinase_fungal PF17667.1 CDO78204.1 - 8.3e-23 80.8 0.0 1.3e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO78205.1 - 2.6e-49 168.1 0.0 4.6e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CDO78205.1 - 0.01 15.8 1.3 0.026 14.5 1.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 CDO78205.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain YrbL-PhoP_reg PF10707.9 CDO78205.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MFS_1 PF07690.16 CDO78208.1 - 4.5e-33 114.6 57.9 2.3e-26 92.6 17.4 3.4 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 CDO78208.1 - 0.15 10.4 15.8 0.0093 14.4 8.9 2.3 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CDO78211.1 - 2e-41 142.1 49.8 4.4e-29 101.5 15.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 CDO78211.1 - 0.36 9.2 15.3 0.034 12.6 9.2 2.3 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CDO78211.1 - 0.66 8.2 22.1 0.017 13.5 1.4 4.0 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family BTB PF00651.31 CDO78212.1 - 0.22 11.8 0.0 1.9 8.7 0.0 2.0 1 1 0 1 1 1 0 BTB/POZ domain RT_RNaseH PF17917.1 CDO78213.1 - 6.6e-38 129.2 0.0 1.1e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO78213.1 - 1.1e-34 118.4 0.0 2.7e-34 117.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO78213.1 - 2.2e-32 112.4 0.0 3.8e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CDO78213.1 - 1.7e-06 27.8 0.0 3.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CDO78213.1 - 5e-06 27.1 0.0 1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CDO78213.1 - 0.0052 17.3 0.0 0.0092 16.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 CDO78213.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Ty3 transposon peptidase Retrotrans_gag PF03732.17 CDO78214.1 - 1.5e-14 54.0 0.0 3.7e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO78214.1 - 1.8e-09 37.4 0.0 5.6e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) Retrotran_gag_2 PF14223.6 CDO78214.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RAP1 PF07218.11 CDO78214.1 - 0.86 7.8 5.6 1.1 7.4 5.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Integrase_H2C2 PF17921.1 CDO78215.1 - 6.2e-10 39.0 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Clathrin-link PF09268.10 CDO78215.1 - 0.035 13.5 0.1 0.073 12.5 0.1 1.5 1 0 0 1 1 1 0 Clathrin, heavy-chain linker rve PF00665.26 CDO78216.1 - 0.0054 16.9 0.0 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Plavaka PF18759.1 CDO78221.1 - 2.7e-123 411.3 0.1 5.1e-123 410.4 0.0 1.5 2 0 0 2 2 2 1 Plavaka transposase zf-Di19 PF05605.12 CDO78221.1 - 0.0098 16.2 1.2 0.69 10.3 0.2 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Pkinase_fungal PF17667.1 CDO78224.1 - 4e-44 151.0 0.0 6.6e-34 117.4 0.0 2.5 2 1 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 CDO78224.1 - 0.21 10.5 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CAP59_mtransfer PF11735.8 CDO78225.1 - 2.3e-67 227.2 0.0 3.1e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Spb1_C PF07780.12 CDO78227.1 - 7.4e-83 277.3 27.5 7.4e-83 277.3 27.5 3.9 5 0 0 5 5 5 1 Spb1 C-terminal domain DUF3381 PF11861.8 CDO78227.1 - 1.9e-47 161.2 7.9 1.9e-47 161.2 7.9 5.9 5 1 0 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.19 CDO78227.1 - 1.3e-36 126.4 0.1 3.4e-36 125.0 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Lar_N PF09861.9 CDO78227.1 - 0.88 8.7 6.1 0.084 12.0 0.7 1.9 2 0 0 2 2 2 0 Lactate racemase N-terminal domain Imm-NTF2 PF15655.6 CDO78227.1 - 1.7 8.9 5.3 0.35 11.2 0.3 2.4 2 0 0 2 2 2 0 NTF2 fold immunity protein SLS PF14611.6 CDO78228.1 - 2.7e-09 37.2 0.0 8.1e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Sugar_tr PF00083.24 CDO78229.1 - 2e-47 162.1 23.6 7.1e-46 157.0 23.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CDO78229.1 - 1.2e-14 54.1 36.3 2.3e-08 33.4 17.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 CDO78229.1 - 0.074 12.9 0.2 0.074 12.9 0.2 3.6 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Metallophos PF00149.28 CDO78233.1 - 2.6e-05 24.8 0.0 4e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDO78233.1 - 0.0003 21.0 0.1 0.019 15.1 0.1 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-CCCH_2 PF14608.6 CDO78234.1 - 1.5e-15 57.0 35.1 5.8e-06 26.6 4.6 4.3 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CDO78234.1 - 0.1 12.4 14.6 2.9 7.8 3.3 4.6 4 1 0 4 4 4 0 CCCH-type zinc finger SpdB PF05122.13 CDO78234.1 - 4.2 7.6 13.3 0.39 10.9 2.4 3.6 2 1 1 3 3 3 0 Mobile element transfer protein OHCU_decarbox PF09349.10 CDO78235.1 - 0.065 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 OHCU decarboxylase Pkinase PF00069.25 CDO78236.1 - 6.2e-39 134.0 0.0 8.7e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CDO78236.1 - 1.5e-18 67.0 0.0 2.2e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CDO78236.1 - 0.00024 20.5 0.0 0.0043 16.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DHHA2 PF02833.14 CDO78237.1 - 1.8e-29 102.7 0.0 2.9e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CDO78237.1 - 1.3e-14 54.2 0.0 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 DHH family Transposase_21 PF02992.14 CDO78241.1 - 2.6e-08 33.4 0.0 3.6e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 CDO78241.1 - 0.032 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Transgly PF00912.22 CDO78241.1 - 0.057 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Transglycosylase Pkinase_fungal PF17667.1 CDO78242.1 - 1.4e-47 162.4 0.0 3.5e-47 161.1 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 CDO78244.1 - 2.9e-46 158.1 0.0 5.9e-46 157.1 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CDO78244.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 CDO78244.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_16 PF13191.6 CDO78245.1 - 7e-08 33.0 0.3 1.4e-06 28.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CDO78245.1 - 6.2e-07 29.5 0.0 3.1e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CDO78245.1 - 1.3e-06 28.7 0.1 5.4e-05 23.5 0.0 3.2 3 1 1 4 4 4 1 AAA domain AAA PF00004.29 CDO78245.1 - 4.7e-05 23.8 0.0 0.0096 16.3 0.0 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 CDO78245.1 - 0.00028 20.1 0.0 0.00048 19.3 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NTPase_1 PF03266.15 CDO78245.1 - 0.0099 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_30 PF13604.6 CDO78245.1 - 0.029 14.1 0.0 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CDO78245.1 - 0.038 13.2 0.0 0.084 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 CDO78245.1 - 0.1 13.1 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 CDO78245.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 CDO78245.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 CDO78245.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase_fungal PF17667.1 CDO78247.1 - 1.3e-12 47.3 0.0 1.3e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CDO78247.1 - 0.022 14.4 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Chromo PF00385.24 CDO78250.1 - 9.2e-07 28.7 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CDO78250.1 - 0.005 16.9 0.0 0.0083 16.2 0.0 1.3 1 0 0 1 1 1 1 Chromo shadow domain gag_pre-integrs PF13976.6 CDO78252.1 - 1.8e-06 27.7 0.0 3.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Dimer_Tnp_hAT PF05699.14 CDO78253.1 - 1.5e-15 56.7 0.0 2.9e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RP-C_C PF11800.8 CDO78254.1 - 1.4 8.9 19.1 2.2 8.3 2.3 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region LisH PF08513.11 CDO78255.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 LisH Pkinase_fungal PF17667.1 CDO78256.1 - 3.2e-26 92.0 0.0 3.9e-21 75.3 0.0 2.4 1 1 1 2 2 2 2 Fungal protein kinase TPT PF03151.16 CDO78258.1 - 0.00014 21.4 4.2 0.00015 21.2 4.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 CDO78258.1 - 0.023 14.0 2.1 0.027 13.7 2.1 1.1 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport IncD PF17628.2 CDO78258.1 - 0.26 11.1 1.8 0.32 10.8 1.8 1.2 1 0 0 1 1 1 0 Inclusion membrane protein D DUF2070 PF09843.9 CDO78258.1 - 0.42 8.8 4.4 0.46 8.7 4.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) p450 PF00067.22 CDO78259.1 - 2.1e-32 112.5 0.0 3.3e-27 95.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 CDO78260.1 - 9.8e-79 265.2 0.0 1.2e-78 265.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ArfGap PF01412.18 CDO78261.1 - 1.6e-11 44.3 0.1 3.5e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Mre11_DNA_bind PF04152.14 CDO78264.1 - 3.6e-26 92.5 3.4 2.2e-14 54.2 0.0 3.6 2 2 1 3 3 3 2 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CDO78264.1 - 6e-14 53.0 0.6 1.2e-13 52.1 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CDO78264.1 - 7.7e-05 23.0 0.0 0.0014 18.9 0.0 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPT PF03151.16 CDO78265.1 - 5.4e-20 71.9 21.3 6.5e-20 71.6 21.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CDO78265.1 - 4.8e-07 30.0 35.5 0.001 19.2 14.6 2.4 2 1 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 CDO78265.1 - 0.0023 16.3 13.2 0.0023 16.3 13.2 2.0 1 1 1 2 2 2 1 Predicted membrane protein (DUF2070) NTP_transf_8 PF12281.8 CDO78265.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase DUF3995 PF13160.6 CDO78265.1 - 9.9 6.5 14.7 0.092 13.1 1.6 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3995) Dynamin_M PF01031.20 CDO78268.1 - 3.6e-15 55.9 0.0 4e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Dynamin central region betaPIX_CC PF16523.5 CDO78269.1 - 0.27 11.1 1.6 0.61 10.0 1.6 1.6 1 0 0 1 1 1 0 betaPIX coiled coil DDE_3 PF13358.6 CDO78271.1 - 6.6e-17 61.6 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 CDO78271.1 - 2.9e-09 37.0 4.9 5.6e-07 29.7 2.1 3.1 3 0 0 3 3 3 1 Transposase HTH_38 PF13936.6 CDO78271.1 - 1.1e-06 28.2 0.1 3.1e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 CDO78271.1 - 7e-06 25.7 0.1 5.1e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 CDO78271.1 - 5.2e-05 23.3 0.0 5.2e-05 23.3 0.0 3.0 4 0 0 4 4 3 1 Helix-turn-helix domain HTH_IclR PF09339.10 CDO78271.1 - 0.00035 20.3 0.0 0.00088 19.0 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.12 CDO78271.1 - 0.00066 19.6 0.1 0.007 16.3 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.6 CDO78271.1 - 0.0027 17.7 2.6 0.0034 17.4 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_r4 PF04545.16 CDO78271.1 - 0.003 17.1 1.0 0.0053 16.2 0.0 1.9 2 0 0 2 2 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 CDO78271.1 - 0.0046 16.3 0.7 0.023 14.1 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_Crp_2 PF13545.6 CDO78271.1 - 0.0059 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_AraC PF00165.23 CDO78271.1 - 0.0087 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family MarR_2 PF12802.7 CDO78271.1 - 0.0089 15.9 0.7 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 MarR family GntR PF00392.21 CDO78271.1 - 0.02 14.5 0.0 0.062 13.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.15 CDO78271.1 - 0.025 14.6 0.1 2.4 8.3 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MarR PF01047.22 CDO78271.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 CDO78271.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.6 CDO78271.1 - 0.15 12.0 2.3 0.41 10.5 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Phage_NinH PF06322.11 CDO78271.1 - 0.18 11.7 1.9 0.38 10.7 0.1 2.2 2 0 0 2 2 2 0 Phage NinH protein Cpn60_TCP1 PF00118.24 CDO78272.1 - 1.5e-137 459.2 16.8 1.4e-101 340.6 7.2 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 CDO78272.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat PMT PF02366.18 CDO78273.1 - 3.8e-81 272.3 14.2 7.8e-81 271.3 14.2 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CDO78273.1 - 3e-68 229.3 11.2 6.1e-68 228.3 11.2 1.5 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CDO78273.1 - 4.6e-40 137.4 0.5 9.3e-40 136.5 0.5 1.5 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 CDO78273.1 - 0.00026 21.2 9.9 0.00026 21.2 9.9 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase UQ_con PF00179.26 CDO78273.1 - 0.16 11.7 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme INO80_Ies4 PF08193.11 CDO78273.1 - 0.85 9.6 9.2 1.5 8.8 9.2 1.3 1 0 0 1 1 1 0 INO80 complex subunit Ies4 Cyclin_N PF00134.23 CDO78274.1 - 1.5e-07 31.2 0.2 1.5e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CDO78274.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain AJAP1_PANP_C PF15298.6 CDO78274.1 - 0.12 12.6 0.4 0.18 12.0 0.4 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Cyclin_C PF02984.19 CDO78274.1 - 0.42 10.7 5.6 1.1 9.3 2.6 2.6 2 1 0 2 2 2 0 Cyclin, C-terminal domain CoaE PF01121.20 CDO78275.1 - 2.9e-07 30.3 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase Dimer_Tnp_hAT PF05699.14 CDO78277.1 - 2.8e-12 46.2 0.0 1e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CDO78277.1 - 0.25 11.4 3.6 0.4 10.8 0.2 3.0 4 0 0 4 4 4 0 BED zinc finger Retrotran_gag_2 PF14223.6 CDO78278.1 - 7.5e-25 87.2 0.0 9.6e-25 86.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO78278.1 - 3.7e-05 23.6 2.2 3.7e-05 23.6 2.2 1.6 2 0 0 2 2 2 1 Zinc knuckle DUF4219 PF13961.6 CDO78278.1 - 0.00022 20.8 1.4 0.00025 20.6 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) zf-CCHC_2 PF13696.6 CDO78278.1 - 0.0048 16.7 3.2 0.0078 16.0 3.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CDO78278.1 - 0.059 13.4 0.5 0.13 12.2 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 CDO78279.1 - 5.6e-37 126.2 0.0 1.1e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CDO78279.1 - 5.7e-32 109.7 0.0 1.2e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CDO78279.1 - 1.7e-28 99.6 0.0 3.1e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 CDO78279.1 - 3.4e-10 40.1 1.0 1.2e-09 38.3 0.0 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4939 PF16297.5 CDO78279.1 - 2.6e-07 30.5 0.0 8.1e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4939) Asp_protease_2 PF13650.6 CDO78279.1 - 0.055 14.1 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RGCC PF15151.6 CDO78279.1 - 3.3 7.9 5.6 8.3 6.6 5.6 1.6 1 0 0 1 1 1 0 Response gene to complement 32 protein family FAM83 PF07894.12 CDO78279.1 - 4.1 6.9 5.3 2.2 7.7 2.5 1.8 2 0 0 2 2 2 0 FAM83 A-H RVT_2 PF07727.14 CDO78280.1 - 2.8e-67 226.9 0.0 4.4e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CDO78280.1 - 2.1e-12 47.3 0.0 8.4e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 CDO78280.1 - 1e-05 25.3 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 CDO78280.1 - 0.0031 17.5 3.7 0.0068 16.4 3.7 1.6 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.6 CDO78280.1 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_5 PF14787.6 CDO78280.1 - 0.15 11.8 1.8 0.36 10.6 1.8 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Retrotran_gag_2 PF14223.6 CDO78281.1 - 5.9e-11 42.2 0.1 7.1e-11 41.9 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2953 PF11167.8 CDO78282.1 - 0.046 13.8 3.7 0.37 10.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) GMC_oxred_N PF00732.19 CDO78283.1 - 6.4e-55 186.6 0.0 8.9e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CDO78283.1 - 7.3e-06 26.6 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CDO78283.1 - 0.0037 17.5 0.2 0.019 15.2 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CDO78283.1 - 0.0038 16.5 0.1 0.0093 15.2 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 CDO78283.1 - 0.01 15.1 0.9 0.13 11.5 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CDO78283.1 - 0.028 13.5 0.4 0.052 12.6 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CDO78283.1 - 0.046 12.8 0.1 0.069 12.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 CDO78283.1 - 0.17 11.4 1.0 0.24 11.0 1.1 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase F-box PF00646.33 CDO78285.1 - 1.4e-08 34.4 0.5 3.1e-08 33.3 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CDO78285.1 - 7.4e-08 32.2 0.6 1.5e-07 31.2 0.6 1.5 1 0 0 1 1 1 1 F-box-like GLE1 PF07817.13 CDO78286.1 - 0.057 12.6 0.4 0.084 12.1 0.4 1.2 1 0 0 1 1 1 0 GLE1-like protein DUF659 PF04937.15 CDO78287.1 - 2.6e-08 33.9 0.0 5.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 CDO78287.1 - 0.0015 18.2 0.0 0.0048 16.7 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region SNF2_N PF00176.23 CDO78288.1 - 2.7e-63 213.8 0.0 1.6e-61 207.9 0.0 2.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CDO78288.1 - 3.8e-16 59.4 0.0 1.4e-15 57.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CDO78288.1 - 3e-07 30.6 1.1 0.0014 18.7 0.0 3.4 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CDO78288.1 - 5.5e-06 25.8 0.0 3e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Pinin_SDK_N PF04697.13 CDO78288.1 - 0.0031 18.2 9.7 0.0031 18.2 9.7 2.9 3 0 0 3 3 3 1 pinin/SDK conserved region SWI2_SNF2 PF18766.1 CDO78288.1 - 0.012 15.3 0.1 0.047 13.4 0.0 2.1 2 0 0 2 2 2 0 SWI2/SNF2 ATPase AA_permease_2 PF13520.6 CDO78289.1 - 6.6e-68 229.5 33.0 8.5e-68 229.1 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CDO78289.1 - 2e-14 53.1 30.1 2.4e-14 52.8 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease ATP-synt_S1 PF05827.12 CDO78289.1 - 4.2 7.2 5.8 6.4 6.6 0.4 2.9 2 1 1 3 3 3 0 Vacuolar ATP synthase subunit S1 (ATP6S1) RabGAP-TBC PF00566.18 CDO78290.1 - 4.9e-30 104.8 0.0 6.9e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.17 CDO78290.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain TetR_C_28 PF17937.1 CDO78291.1 - 0.051 14.0 0.1 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RVT_3 PF13456.6 CDO78291.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 Reverse transcriptase-like DUF5122 PF17164.4 CDO78292.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller DDE_Tnp_4 PF13359.6 CDO78293.1 - 1.2e-16 60.7 0.0 1.5e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CDO78293.1 - 2e-05 24.4 0.0 6.1e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 CDO78293.1 - 0.041 13.5 0.0 0.066 12.8 0.0 1.5 1 1 0 1 1 1 0 Plant transposon protein Myb_DNA-bind_3 PF12776.7 CDO78294.1 - 6.7e-05 23.8 0.1 0.00016 22.6 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CDO78294.1 - 7.4e-05 23.1 0.2 0.00025 21.4 0.0 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CDO78294.1 - 0.02 15.1 0.3 0.077 13.2 0.3 2.1 1 1 0 1 1 1 0 Myb-like DNA-binding domain Mito_fiss_reg PF05308.11 CDO78294.1 - 1.3 9.1 5.7 2.5 8.1 5.7 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA_16 PF13191.6 CDO78295.1 - 0.0058 17.0 0.2 0.046 14.1 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Goodbye PF17109.5 CDO78295.1 - 0.0072 16.8 0.0 0.059 13.8 0.0 2.3 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 CDO78295.1 - 0.068 13.4 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Tektin PF03148.14 CDO78295.1 - 0.077 11.7 0.9 1.5 7.5 0.1 2.2 2 0 0 2 2 2 0 Tektin family NB-ARC PF00931.22 CDO78295.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain IL31 PF15209.6 CDO78295.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Interleukin 31 XhlA PF10779.9 CDO78295.1 - 0.18 12.0 0.1 2.8 8.2 0.0 2.7 3 0 0 3 3 3 0 Haemolysin XhlA Retrotran_gag_2 PF14223.6 CDO78296.1 - 5.3e-17 61.8 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 CDO78296.1 - 8.8e-08 31.6 0.3 2e-07 30.5 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) CPSF100_C PF13299.6 CDO78296.1 - 0.57 10.3 6.1 0.13 12.4 2.0 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal XRN_N PF03159.18 CDO78296.1 - 0.74 9.2 4.2 1.2 8.5 2.2 2.0 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Spt20 PF12090.8 CDO78296.1 - 2 8.0 7.6 3.1 7.3 7.6 1.2 1 0 0 1 1 1 0 Spt20 family # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trametes_cinnabarina-BN946/GCA_000765035.1_BN946_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trametes_cinnabarina-BN946/GCA_000765035.1_BN946_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trametes_cinnabarina-BN946/GCA_000765035.1_BN946_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trametes_cinnabarina-BN946/GCA_000765035.1_BN946_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 07:32:09 2019 # [ok]