# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- CBM_1 PF00734.13 CDO68064.1 - 7 6.4 8.0 16 5.2 3.8 2.6 2 1 0 2 2 2 0 Fungal cellulose binding domain Aconitase PF00330.15 CDO68065.1 - 6.6e-76 255.6 0.4 7.3e-44 150.0 0.0 3.1 2 1 0 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CDO68065.1 - 2.9e-19 69.4 0.0 5.2e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 CDO68065.1 - 0.021 13.3 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MIB_HERC2 PF06701.8 CDO68065.1 - 0.12 12.4 1.1 0.25 11.3 0.7 1.5 1 0 0 1 1 1 0 Mib_herc2 AMP-binding PF00501.23 CDO68066.1 - 4.5e-85 285.5 0.0 6.2e-85 285.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CDO68066.1 - 0.0017 19.2 0.0 0.025 15.4 0.0 2.5 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 CDO68067.1 - 1.3e-58 198.6 0.0 1.6e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF745 PF05335.8 CDO68068.1 - 0.015 14.8 0.6 0.027 13.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF812 PF05667.6 CDO68068.1 - 0.16 10.4 0.1 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) RVT_1 PF00078.22 CDO68069.1 - 4.3e-20 71.9 0.0 8.3e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO68069.1 - 3.3e-14 53.3 0.0 6.4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 CDO68069.1 - 3.6e-08 33.0 0.1 7.7e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CDO68069.1 - 9.5e-07 28.9 2.8 2.6e-06 27.5 1.9 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PSD4 PF07631.6 CDO68071.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1592) EAP30 PF04157.11 CDO68073.1 - 3.1e-32 111.5 0.0 4.7e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CDO68073.1 - 5.3e-23 80.6 0.0 9.3e-23 79.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 CDO68073.1 - 0.00014 20.8 11.5 0.021 13.9 1.0 2.6 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 CDO68073.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 GRAM domain DZR PF12773.2 CDO68073.1 - 0.14 11.9 4.2 0.4 10.5 0.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon DUF4589 PF15252.1 CDO68074.1 - 0.058 13.2 1.4 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) DUF3446 PF11928.3 CDO68074.1 - 1.2 9.4 12.6 1.7 8.9 3.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) VCBS PF13517.1 CDO68076.1 - 0.00023 21.4 3.5 0.0024 18.1 0.0 3.6 3 1 2 5 5 5 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CDO68076.1 - 0.0018 17.8 0.3 0.026 14.2 0.0 3.0 2 0 0 2 2 2 1 FG-GAP repeat DUF1687 PF07955.6 CDO68077.1 - 6.3e-09 35.9 0.0 8.1e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Prefoldin PF02996.12 CDO68078.1 - 5.9e-27 93.6 0.5 1.5e-25 89.1 0.3 2.1 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CDO68078.1 - 0.045 13.5 1.4 0.18 11.5 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.6 CDO68078.1 - 0.056 13.8 1.0 0.86 10.0 0.2 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal RRM_1 PF00076.17 CDO68079.1 - 2e-65 216.3 0.0 2.7e-19 68.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO68079.1 - 3.9e-55 183.7 0.1 1.4e-14 53.7 0.0 5.7 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO68079.1 - 3.6e-26 90.7 0.0 6e-08 32.4 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CDO68079.1 - 2.3e-05 24.0 0.0 16 5.3 0.0 5.6 5 3 0 5 5 5 3 Limkain b1 STE3 PF02076.10 CDO68081.1 - 2.7e-91 305.5 16.4 3.2e-91 305.3 11.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor MFS_1 PF07690.11 CDO68082.1 - 7e-06 24.9 2.5 7.2e-06 24.9 1.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO68082.1 - 0.002 16.8 0.1 0.0021 16.7 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3325 PF11804.3 CDO68082.1 - 0.048 13.5 0.4 0.059 13.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) Sugar_tr PF00083.19 CDO68083.1 - 8.7e-15 54.2 4.2 8.7e-15 54.2 2.9 1.8 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO68083.1 - 3.6e-13 48.9 29.4 6.2e-13 48.1 20.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2583 PF10762.4 CDO68083.1 - 0.057 13.5 0.5 0.23 11.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Myb_DNA-binding PF00249.26 CDO68084.1 - 2.1e-15 56.5 0.1 1.6e-08 34.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO68084.1 - 2.9e-10 40.1 0.0 3.8e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain PCI PF01399.22 CDO68085.1 - 8.5e-09 35.6 0.1 3.3e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 PCI domain MFS_1 PF07690.11 CDO68086.1 - 2.3e-08 33.1 14.1 2.7e-08 32.9 9.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO68086.1 - 0.0059 15.2 9.3 0.0073 14.9 6.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO68087.1 - 4.4e-07 28.9 15.4 7.4e-06 24.9 11.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 CDO68088.1 - 2.3e-10 40.7 1.9 5e-10 39.6 1.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO68088.1 - 0.00014 21.6 0.0 0.0005 19.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FlgN PF05130.7 CDO68090.1 - 0.011 16.0 7.5 0.022 14.9 5.2 1.5 1 0 0 1 1 1 0 FlgN protein FH2 PF02181.18 CDO68090.1 - 0.11 11.3 0.5 0.21 10.4 0.3 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain SUKH_5 PF14567.1 CDO68090.1 - 0.15 11.4 0.2 0.31 10.4 0.2 1.4 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Zw10 PF06248.8 CDO68090.1 - 0.26 9.3 0.7 0.38 8.8 0.5 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF1515 PF07439.6 CDO68090.1 - 1.3 8.8 3.4 49 3.7 2.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) IncA PF04156.9 CDO68090.1 - 1.8 8.1 5.3 3.5 7.1 3.6 1.4 1 0 0 1 1 1 0 IncA protein HSCB_C PF07743.8 CDO68090.1 - 9 6.8 8.4 18 5.8 2.1 2.5 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain STE3 PF02076.10 CDO68091.1 - 0.00011 21.4 2.0 0.00015 20.9 1.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor Herpes_gE PF02480.11 CDO68093.1 - 0.086 11.0 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3149 PF11346.3 CDO68093.1 - 0.26 10.8 3.5 0.47 10.0 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) zf-C2H2 PF00096.21 CDO68094.1 - 7.4e-08 32.2 10.7 0.0003 20.9 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO68094.1 - 2.2e-05 24.4 3.3 2.2e-05 24.4 2.3 2.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CDO68094.1 - 0.00019 21.4 16.4 0.0058 16.8 0.8 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CDO68094.1 - 0.0083 15.9 2.2 0.044 13.6 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger Metallophos PF00149.23 CDO68096.1 - 2.7e-11 43.2 0.6 3.9e-11 42.7 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDO68096.1 - 0.0001 22.2 0.0 0.00015 21.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DBR1 PF05011.8 CDO68096.1 - 0.019 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Brix PF04427.13 CDO68097.1 - 2.7e-19 69.5 0.0 8.1e-12 45.1 0.0 2.1 1 1 1 2 2 2 2 Brix domain BTB PF00651.26 CDO68099.1 - 0.084 12.8 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain BTB PF00651.26 CDO68100.1 - 0.00022 21.1 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF746 PF05344.6 CDO68101.1 - 0.084 12.4 0.1 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) 2OG-FeII_Oxy_3 PF13640.1 CDO68102.1 - 1.6e-06 28.5 0.5 4e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CDO68102.1 - 4.2e-05 23.7 0.0 7.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CDO68102.1 - 0.03 13.9 0.1 0.22 11.1 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 CDO68103.1 - 1.3e-05 25.6 0.3 1.3e-05 25.6 0.2 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CDO68103.1 - 0.00018 21.7 0.3 0.0017 18.5 0.0 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CDO68103.1 - 0.05 13.2 0.0 0.79 9.4 0.0 2.5 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 CDO68104.1 - 1.4e-41 142.3 0.0 1e-22 80.5 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO68104.1 - 3.4e-13 49.2 0.3 4e-05 22.8 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CDO68104.1 - 0.081 11.7 0.1 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase VGLL4 PF15245.1 CDO68104.1 - 0.2 11.4 1.2 0.53 10.0 0.8 1.6 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 Asp PF00026.18 CDO68106.1 - 7.6e-20 71.3 0.5 8.8e-17 61.3 0.3 2.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CDO68106.1 - 1.3e-06 28.7 4.3 0.00078 19.8 0.9 3.1 3 2 0 3 3 3 2 Aspartyl protease RVP PF00077.15 CDO68106.1 - 0.037 13.9 0.3 0.27 11.1 0.1 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease Lamp PF01299.12 CDO68106.1 - 0.06 12.4 0.3 0.11 11.5 0.2 1.4 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) WD40 PF00400.27 CDO68107.1 - 2.5e-51 169.8 9.3 1e-12 47.3 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 CDO68107.1 - 5.8e-10 37.9 4.2 0.00021 19.6 0.0 4.3 2 1 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CDO68107.1 - 0.0023 17.6 0.0 0.17 11.6 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CDO68107.1 - 0.003 15.9 0.2 0.0086 14.4 0.0 1.7 2 0 0 2 2 2 1 Cytochrome D1 heme domain Peptidase_M13_N PF05649.8 CDO68107.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M13 LisH PF08513.6 CDO68107.1 - 0.14 11.9 1.0 0.28 11.0 0.7 1.5 1 0 0 1 1 1 0 LisH FAP PF07174.6 CDO68110.1 - 0.0069 15.7 3.4 0.0089 15.3 2.4 1.1 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) CAF-1_p150 PF11600.3 CDO68110.1 - 0.031 13.6 27.9 0.052 12.9 19.3 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sad1_UNC PF07738.8 CDO68111.1 - 4.3e-10 39.4 0.0 2.1e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal BUD22 PF09073.5 CDO68115.1 - 3 6.8 13.9 4.9 6.1 9.6 1.2 1 0 0 1 1 1 0 BUD22 F-box-like PF12937.2 CDO68118.1 - 0.0092 15.6 0.1 0.026 14.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 CDO68118.1 - 0.11 12.2 2.7 24 4.7 0.0 3.8 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 CDO68118.1 - 0.17 11.5 6.2 1.5 8.5 0.7 4.0 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) F-box PF00646.28 CDO68118.1 - 0.77 9.4 7.6 12 5.7 0.2 3.8 2 2 1 3 3 3 0 F-box domain DNA_primase_S PF01896.14 CDO68119.1 - 1.3e-53 180.7 0.0 2.1e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit HNH_2 PF13391.1 CDO68119.1 - 0.047 13.4 0.2 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 HNH endonuclease Transposase_21 PF02992.9 CDO68121.1 - 7e-20 71.0 0.0 1.3e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO68121.1 - 0.0095 15.3 0.1 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RAG1 PF12940.2 CDO68121.1 - 0.083 11.2 0.0 0.45 8.7 0.0 1.9 2 0 0 2 2 2 0 Recombination-activation protein 1 (RAG1) CALCOCO1 PF07888.6 CDO68121.1 - 0.69 8.1 3.7 0.39 8.9 0.3 1.9 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Sigma70_ner PF04546.8 CDO68123.1 - 0.012 15.2 4.0 0.019 14.6 2.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region LAT PF15234.1 CDO68123.1 - 0.016 14.7 1.9 0.027 13.9 1.3 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells Nop14 PF04147.7 CDO68123.1 - 0.073 10.9 2.4 0.091 10.6 1.7 1.2 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 CDO68123.1 - 0.25 9.4 1.3 0.31 9.0 0.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.1 CDO68123.1 - 0.73 10.1 4.8 0.73 10.1 1.9 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 CDO68123.1 - 1.1 8.3 9.1 0.77 8.8 5.2 1.5 1 1 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 CDO68123.1 - 2.9 8.1 11.3 6.5 7.0 7.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CM_2 PF01817.16 CDO68124.1 - 0.0086 16.1 1.5 0.024 14.7 0.9 1.7 1 1 1 2 2 2 2 Chorismate mutase type II rve PF00665.21 CDO68125.1 - 7.9e-11 42.1 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CDO68125.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 DDE domain Mannitol_dh_C PF08125.8 CDO68125.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain CM_2 PF01817.16 CDO68126.1 - 0.038 14.0 1.3 0.091 12.8 0.9 1.7 1 1 0 1 1 1 0 Chorismate mutase type II DUF605 PF04652.11 CDO68126.1 - 1.9 7.8 7.8 2 7.7 5.4 1.2 1 0 0 1 1 1 0 Vta1 like Nop10p PF04135.7 CDO68127.1 - 0.012 15.3 3.4 2.5 7.8 0.1 2.8 3 0 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family Asp_protease_2 PF13650.1 CDO68128.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease UBN2_2 PF14227.1 CDO68129.1 - 8.9e-10 38.1 0.0 1.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO68129.1 - 9.4e-06 25.4 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO68130.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type p450 PF00067.17 CDO68134.1 - 1.5e-70 238.0 0.0 2.1e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CDO68135.1 - 1.3e-72 244.8 0.0 1.7e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tubulin PF00091.20 CDO68136.1 - 1e-67 228.1 0.0 1.4e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CDO68136.1 - 2.7e-45 153.4 0.0 4e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CDO68136.1 - 0.0004 19.9 0.0 0.00074 19.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CDO68136.1 - 0.039 13.9 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Lipase_3 PF01764.20 CDO68136.1 - 0.044 13.3 0.0 0.96 9.0 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Tubulin PF00091.20 CDO68137.1 - 1.9e-66 224.0 0.0 2.6e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CDO68137.1 - 5.5e-46 155.6 0.0 8.4e-46 155.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CDO68137.1 - 7.4e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Abhydrolase_3 PF07859.8 CDO68138.1 - 1.8e-27 96.3 0.3 1.5e-19 70.4 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CDO68138.1 - 7.3e-05 21.5 0.1 0.00038 19.1 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Protoglobin PF11563.3 CDO68139.1 - 8.3e-40 136.0 0.0 9.8e-40 135.7 0.0 1.1 1 0 0 1 1 1 1 Protoglobin DUF3245 PF11595.3 CDO68140.1 - 5.6e-05 23.4 15.8 5.6e-05 23.4 11.0 4.5 3 1 0 3 3 3 1 Protein of unknown function (DUF3245) DUF2702 PF10863.3 CDO68140.1 - 0.06 13.0 0.0 0.06 13.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2702) G-patch_2 PF12656.2 CDO68140.1 - 0.091 12.6 0.0 0.091 12.6 0.0 3.7 4 0 0 4 4 4 0 DExH-box splicing factor binding site SIP1 PF04938.7 CDO68141.1 - 1.3e-15 57.4 0.8 1.6e-14 53.7 0.5 2.1 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) GPI-anchored PF10342.4 CDO68142.1 - 2.7e-13 50.2 1.4 2.7e-13 50.2 1.0 2.1 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family QRPTase_C PF01729.14 CDO68143.1 - 4.5e-50 169.4 0.0 5.6e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 CDO68143.1 - 3.1e-22 78.2 0.0 1e-21 76.5 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Amidohydro_2 PF04909.9 CDO68144.1 - 2.2e-27 96.3 2.9 2.4e-26 92.9 2.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Asparaginase PF00710.15 CDO68144.1 - 0.052 12.4 0.0 0.078 11.8 0.0 1.1 1 0 0 1 1 1 0 Asparaginase TatD_DNase PF01026.16 CDO68144.1 - 0.12 11.5 0.0 0.36 10.0 0.0 1.7 2 0 0 2 2 2 0 TatD related DNase ECH PF00378.15 CDO68145.1 - 3.5e-62 209.7 0.0 3.5e-62 209.7 0.0 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family DUF904 PF06005.7 CDO68145.1 - 0.013 15.7 1.2 0.013 15.7 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Cep57_CLD_2 PF14197.1 CDO68145.1 - 0.032 14.1 11.7 0.91 9.5 3.7 3.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF1875 PF08961.5 CDO68145.1 - 0.037 13.3 1.6 0.11 11.8 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) FUSC PF04632.7 CDO68145.1 - 0.043 12.2 10.5 0.089 11.2 7.3 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1515 PF07439.6 CDO68145.1 - 0.27 11.0 4.4 0.19 11.5 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Cortex-I_coil PF09304.5 CDO68145.1 - 0.47 10.5 13.4 3.1 7.8 5.4 3.2 2 1 1 3 3 3 0 Cortexillin I, coiled coil DUF972 PF06156.8 CDO68145.1 - 0.84 10.0 3.1 2.6 8.4 2.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.6 CDO68145.1 - 1.2 7.7 4.4 1.9 7.1 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.13 CDO68145.1 - 3 7.6 8.6 14 5.4 0.7 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 CDO68145.1 - 3.3 7.2 9.6 31 4.0 6.5 2.4 2 1 0 2 2 2 0 IncA protein COG2 PF06148.6 CDO68145.1 - 4.4 7.1 6.6 1.5 8.7 1.3 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec10 PF07393.6 CDO68146.1 - 7e-208 692.2 0.1 2.6e-172 574.6 0.0 2.9 2 1 0 2 2 2 2 Exocyst complex component Sec10 Filament PF00038.16 CDO68146.1 - 0.1 12.0 3.1 0.22 10.9 1.9 1.7 1 1 0 1 1 1 0 Intermediate filament protein Ytp1 PF10355.4 CDO68147.1 - 1.1e-91 306.8 7.8 1.5e-91 306.3 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CDO68147.1 - 3.6e-16 58.6 0.6 3.6e-16 58.6 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Dimer_Tnp_hAT PF05699.9 CDO68148.1 - 6.8e-09 35.2 0.0 1.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Myb_DNA-bind_3 PF12776.2 CDO68149.1 - 3.2e-08 34.0 0.0 8.2e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain AIP3 PF03915.8 CDO68150.1 - 9.8e-98 327.8 22.5 2.7e-82 276.9 3.6 2.6 2 1 1 3 3 3 2 Actin interacting protein 3 FlaC_arch PF05377.6 CDO68150.1 - 0.0017 18.2 7.5 0.29 11.0 0.3 4.1 2 2 1 3 3 3 2 Flagella accessory protein C (FlaC) DIRP PF06584.8 CDO68150.1 - 0.048 13.5 2.9 0.1 12.4 0.1 2.5 2 0 0 2 2 2 0 DIRP WXG100 PF06013.7 CDO68150.1 - 0.49 10.4 8.2 9.9 6.2 0.5 3.8 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.6 CDO68150.1 - 1.6 9.1 17.1 0.69 10.3 0.3 4.7 3 1 2 5 5 5 0 Syntaxin 6, N-terminal Ustilago_mating PF05722.7 CDO68152.1 - 0.021 14.1 3.2 0.026 13.8 2.2 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Macoilin PF09726.4 CDO68152.1 - 9.7 4.3 6.6 13 3.9 4.6 1.1 1 0 0 1 1 1 0 Transmembrane protein He_PIG PF05345.7 CDO68153.1 - 4.5e-10 39.3 19.0 9.6e-07 28.7 3.7 5.0 4 0 0 4 4 4 4 Putative Ig domain Big_3_4 PF13754.1 CDO68153.1 - 0.014 15.7 2.1 0.014 15.7 1.4 3.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DDE_1 PF03184.14 CDO68154.1 - 7.1e-46 156.0 0.0 1.1e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease MFS_1 PF07690.11 CDO68154.1 - 3.5e-12 45.7 21.5 2.6e-10 39.5 12.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_Tnp_Tc5 PF03221.11 CDO68154.1 - 6.8e-11 41.8 0.0 1.8e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain OPT PF03169.10 CDO68155.1 - 4.7e-148 494.3 40.9 5.3e-148 494.2 28.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Dynein_light PF01221.13 CDO68156.1 - 2.8e-41 139.3 0.7 3.4e-41 139.1 0.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Toxin_1 PF00087.16 CDO68159.1 - 0.11 12.8 1.1 0.28 11.5 0.7 1.6 1 0 0 1 1 1 0 Snake toxin UPAR_LY6 PF00021.16 CDO68159.1 - 0.34 11.3 3.4 0.34 11.3 0.9 2.1 2 0 0 2 2 2 0 u-PAR/Ly-6 domain Tmemb_cc2 PF10267.4 CDO68159.1 - 0.75 8.3 2.7 0.84 8.1 1.8 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.4 CDO68159.1 - 0.83 7.8 5.1 0.88 7.7 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DHBP_synthase PF00926.14 CDO68160.1 - 3.8e-15 55.6 0.0 5.6e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Mito_carr PF00153.22 CDO68161.1 - 1.8e-34 117.2 6.5 7.5e-19 67.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein COesterase PF00135.23 CDO68162.1 - 1.8e-97 327.2 0.0 2.5e-96 323.5 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CDO68162.1 - 0.00041 19.6 0.5 0.00067 18.9 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CDO68162.1 - 0.003 17.1 0.5 0.01 15.4 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 CDO68162.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) COesterase PF00135.23 CDO68163.1 - 9.8e-28 97.1 0.0 1.1e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.23 CDO68164.1 - 9e-12 44.4 0.0 1.8e-09 36.8 0.0 2.9 1 1 0 1 1 1 1 Carboxylesterase family zf-RING_2 PF13639.1 CDO68165.1 - 1.4e-05 24.8 1.2 0.001 18.8 0.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CDO68165.1 - 0.00012 22.1 0.1 0.00028 20.9 0.0 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDO68165.1 - 0.0049 16.4 0.2 0.015 14.9 0.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDO68165.1 - 0.051 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CDO68165.1 - 0.3 11.0 1.5 1.2 9.0 0.1 2.4 3 0 0 3 3 3 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 CDO68165.1 - 0.42 10.6 3.2 0.31 11.0 0.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FAM196 PF15265.1 CDO68166.1 - 1.2 8.3 5.7 1.5 7.9 3.9 1.1 1 0 0 1 1 1 0 FAM196 family MTBP_C PF14920.1 CDO68166.1 - 1.6 8.1 9.8 2.5 7.4 6.8 1.2 1 0 0 1 1 1 0 MDM2-binding Glyco_hydro_32N PF00251.15 CDO68168.1 - 1.8e-81 273.8 1.8 2.3e-81 273.5 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CDO68168.1 - 0.00093 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal LRR_8 PF13855.1 CDO68169.1 - 5e-09 35.7 1.7 1.3e-08 34.4 0.9 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 CDO68169.1 - 2.5e-08 33.3 3.9 5.6e-08 32.2 1.2 2.7 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDO68169.1 - 2.3e-05 23.7 0.7 2.6 8.4 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 CDO68169.1 - 6.3e-05 22.5 0.9 1.9 9.0 0.1 4.2 4 0 0 4 4 4 2 Leucine rich repeat Glyco_hydro_16 PF00722.16 CDO68170.1 - 3.9e-32 111.0 0.0 4.8e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 AIRS PF00586.19 CDO68170.1 - 0.04 14.1 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain AAA_22 PF13401.1 CDO68171.1 - 0.089 12.9 0.4 0.92 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ribosomal_S11 PF00411.14 CDO68171.1 - 3.7 7.7 8.7 1.2 9.3 3.6 2.0 2 0 0 2 2 2 0 Ribosomal protein S11 Fungal_trans PF04082.13 CDO68172.1 - 6.2e-27 94.0 0.0 1.5e-26 92.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain YL1 PF05764.8 CDO68173.1 - 4.4 6.8 11.8 0.074 12.6 2.4 2.0 2 0 0 2 2 2 0 YL1 nuclear protein Methyltransf_10 PF05971.7 CDO68174.1 - 1.2e-30 106.7 0.0 1.7e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) BTB PF00651.26 CDO68176.1 - 1.1e-06 28.5 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Thiolase_N PF00108.18 CDO68177.1 - 1.2e-84 283.4 1.9 1.2e-84 283.4 1.3 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CDO68177.1 - 6.2e-43 145.1 0.6 1.3e-42 144.0 0.4 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CDO68177.1 - 0.016 14.6 2.1 0.62 9.5 0.2 3.1 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CDO68177.1 - 0.049 13.3 0.5 10 5.8 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WES_acyltransf PF03007.11 CDO68178.1 - 1.8e-21 76.9 0.3 3.7e-21 75.8 0.2 1.4 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.8 CDO68178.1 - 0.043 13.6 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) HEAT_EZ PF13513.1 CDO68179.1 - 1e-17 64.0 7.9 0.00012 22.4 0.0 11.5 13 1 1 14 14 14 2 HEAT-like repeat HEAT_2 PF13646.1 CDO68179.1 - 1.3e-16 60.6 5.5 0.0092 16.2 0.1 7.7 3 1 6 9 9 9 7 HEAT repeats HEAT PF02985.17 CDO68179.1 - 8.8e-15 53.4 14.9 0.0049 16.8 0.0 9.2 11 0 0 11 11 11 3 HEAT repeat IBN_N PF03810.14 CDO68179.1 - 1.4e-09 37.7 3.5 6.8e-08 32.3 0.2 3.5 3 1 1 4 4 4 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 CDO68179.1 - 0.00047 18.6 1.7 0.41 8.8 0.0 4.5 6 0 0 6 6 6 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CDO68179.1 - 0.00049 20.4 0.0 0.2 12.0 0.0 4.7 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 CDO68179.1 - 0.00056 19.8 0.0 27 4.7 0.0 5.3 4 1 1 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation RIX1 PF08167.7 CDO68179.1 - 0.0011 18.6 0.9 0.76 9.4 0.1 4.1 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 CDO68179.1 - 0.05 13.4 0.1 18 5.1 0.0 3.3 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 ASL_C PF08328.6 CDO68180.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal RanGAP1_C PF07834.6 CDO68180.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 RanGAP1 C-terminal domain Phosducin PF02114.11 CDO68181.1 - 9.3e-15 54.0 0.0 9.9e-06 24.4 0.0 3.1 3 0 0 3 3 3 3 Phosducin Ribosomal_L30 PF00327.15 CDO68182.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e FlxA PF14282.1 CDO68184.1 - 0.00071 19.4 0.5 0.0074 16.2 0.0 2.5 3 0 0 3 3 3 1 FlxA-like protein Herpes_UL25 PF01499.11 CDO68184.1 - 0.14 10.4 1.1 0.22 9.7 0.8 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family IncA PF04156.9 CDO68184.1 - 0.52 9.8 5.8 72 2.8 0.0 2.6 2 1 0 2 2 2 0 IncA protein DUF4407 PF14362.1 CDO68184.1 - 0.94 8.3 4.0 0.28 10.1 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1192 PF06698.6 CDO68184.1 - 5.2 6.9 8.6 2.2 8.1 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) zf-C2HC5 PF06221.8 CDO68185.1 - 2.5e-13 49.5 3.3 4.6e-13 48.7 2.3 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-Di19 PF05605.7 CDO68185.1 - 0.075 13.1 0.1 0.55 10.3 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 CDO68185.1 - 0.35 10.7 3.9 1.5 8.7 2.7 2.1 1 1 0 1 1 1 0 Double zinc ribbon GATA PF00320.22 CDO68187.1 - 5.6e-09 35.2 6.2 9.3e-09 34.4 4.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Lipase_GDSL PF00657.17 CDO68188.1 - 4.2e-16 59.4 0.0 5.7e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CDO68188.1 - 0.00036 20.7 0.7 0.0032 17.6 0.5 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GST_N PF02798.15 CDO68190.1 - 2.4e-20 72.4 0.0 4.9e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CDO68190.1 - 1.6e-16 60.2 0.0 2.6e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO68190.1 - 2.9e-13 49.6 0.0 4.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CDO68190.1 - 4e-11 42.7 0.0 5.5e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO68190.1 - 2.3e-06 27.3 0.0 3.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO68190.1 - 0.0055 17.1 0.0 0.0065 16.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1672 PF07901.6 CDO68191.1 - 0.02 13.9 0.0 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1672) DHO_dh PF01180.16 CDO68192.1 - 8.4e-92 307.2 0.0 1e-91 306.9 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CDO68192.1 - 0.00019 20.4 0.0 0.00098 18.0 0.1 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 CDO68192.1 - 0.046 12.8 0.0 0.18 10.9 0.0 1.9 2 0 0 2 2 2 0 Nitronate monooxygenase PcrB PF01884.12 CDO68192.1 - 0.11 11.7 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 PcrB family Velvet PF11754.3 CDO68197.1 - 1.7e-23 83.2 0.0 3.6e-23 82.2 0.0 1.4 1 1 0 1 1 1 1 Velvet factor PBP1_TM PF14812.1 CDO68197.1 - 0.3 11.4 4.9 0.61 10.4 3.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 CDO68197.1 - 0.57 7.9 2.5 0.8 7.4 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LAT PF15234.1 CDO68197.1 - 1.2 8.5 5.2 0.49 9.8 0.7 2.4 2 1 1 3 3 3 0 Linker for activation of T-cells PKD_channel PF08016.7 CDO68198.1 - 0.043 12.2 0.5 0.12 10.7 0.1 1.9 2 1 0 2 2 2 0 Polycystin cation channel YjbE PF11106.3 CDO68199.1 - 0.0019 18.0 6.6 0.0019 18.0 4.6 2.1 2 0 0 2 2 2 1 Exopolysaccharide production protein YjbE ERG4_ERG24 PF01222.12 CDO68200.1 - 2.9e-131 437.9 26.3 3.3e-131 437.7 18.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CDO68200.1 - 3.3e-06 26.5 2.4 6.8e-06 25.5 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CDO68200.1 - 0.0029 17.6 0.2 0.0029 17.6 0.1 3.9 4 2 0 4 4 4 1 Phospholipid methyltransferase Lamprin PF06403.6 CDO68200.1 - 0.02 14.6 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 Lamprin ICMT PF04140.9 CDO68200.1 - 0.022 14.9 1.5 0.061 13.5 0.0 2.5 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DWNN PF08783.6 CDO68201.1 - 1.7e-28 98.3 2.3 1.9e-28 98.1 0.3 2.0 2 0 0 2 2 2 1 DWNN domain zf-C3HC4_2 PF13923.1 CDO68201.1 - 0.00082 19.3 7.1 0.00082 19.3 4.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO68201.1 - 0.0073 16.1 6.4 0.0073 16.1 4.4 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CDO68201.1 - 0.025 14.2 4.2 0.046 13.3 2.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trm112p PF03966.11 CDO68201.1 - 0.056 13.8 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 Trm112p-like protein zf-CCHC_2 PF13696.1 CDO68201.1 - 0.069 12.6 0.2 0.19 11.2 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle Borrelia_P83 PF05262.6 CDO68201.1 - 0.33 9.1 5.4 0.53 8.4 3.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-RING_5 PF14634.1 CDO68201.1 - 0.83 9.4 6.1 1.6 8.5 4.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CDO68201.1 - 1.2 8.9 6.9 2.7 7.7 4.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RED_N PF07808.8 CDO68201.1 - 1.4 8.0 6.0 2.9 7.0 4.1 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF2361 PF10153.4 CDO68201.1 - 2.6 8.2 6.9 1.7 8.8 0.7 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) Vps5 PF09325.5 CDO68202.1 - 6.6e-66 221.9 5.3 8.7e-66 221.5 3.6 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CDO68202.1 - 1.1e-27 96.1 0.3 2.9e-26 91.4 0.0 2.3 2 0 0 2 2 2 1 PX domain BAR PF03114.13 CDO68202.1 - 3.2e-07 30.1 2.8 4.4e-07 29.6 2.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.4 CDO68202.1 - 0.023 13.9 1.1 0.19 10.9 0.7 2.1 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Arfaptin PF06456.8 CDO68202.1 - 0.044 13.1 2.4 0.26 10.5 1.6 1.9 1 1 0 1 1 1 0 Arfaptin-like domain p450 PF00067.17 CDO68203.1 - 1.1e-62 212.0 0.0 1.4e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PMT PF02366.13 CDO68204.1 - 4.1e-77 258.8 19.1 7.7e-77 257.9 13.3 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CDO68204.1 - 2.9e-12 46.5 0.4 5.7e-12 45.5 0.2 1.5 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 CDO68204.1 - 3.2e-06 27.1 15.7 3.2e-06 27.1 10.9 2.5 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WTF PF03303.8 CDO68204.1 - 0.76 9.1 3.3 4.2 6.7 2.0 2.1 2 0 0 2 2 2 0 WTF protein WD40 PF00400.27 CDO68205.1 - 2.7e-53 176.0 2.4 3.4e-10 39.3 0.0 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 CDO68205.1 - 8e-13 47.4 2.7 8e-13 47.4 1.9 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 CDO68205.1 - 0.014 14.5 0.0 8.5 5.3 0.0 3.2 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 CDO68205.1 - 0.1 10.7 3.2 1.7 6.6 0.5 3.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 F-box-like PF12937.2 CDO68206.1 - 0.0092 15.6 0.3 0.025 14.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.2 CDO68207.1 - 3.4e-13 49.7 2.3 4.8e-07 30.0 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDO68207.1 - 1.1e-11 44.9 0.7 1.1e-06 29.0 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 CDO68207.1 - 2.8e-11 42.6 9.4 1.8e-05 24.2 0.2 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CDO68207.1 - 6e-10 39.0 2.6 0.00024 21.2 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO68207.1 - 6.2e-10 38.3 5.3 0.0056 16.8 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 CDO68207.1 - 0.00012 21.6 0.1 0.0021 17.6 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Filament PF00038.16 CDO68207.1 - 0.039 13.4 1.2 0.067 12.6 0.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein Phage_GP20 PF06810.6 CDO68207.1 - 0.22 10.9 1.2 0.42 10.0 0.9 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 IMD PF08397.6 CDO68207.1 - 0.25 10.6 1.2 0.42 9.8 0.9 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain PX PF00787.19 CDO68208.1 - 5.8e-15 55.0 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 PX domain UBN2 PF14223.1 CDO68210.1 - 3.1e-12 46.3 0.0 4.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CDO68210.1 - 7.8e-12 44.8 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO68210.1 - 5.3e-06 26.0 0.0 8.4e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Saccharop_dh PF03435.13 CDO68211.1 - 1.3e-107 360.1 0.2 4e-107 358.5 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 CDO68211.1 - 2.1e-94 315.0 0.0 3.8e-94 314.2 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Shikimate_DH PF01488.15 CDO68211.1 - 1e-06 28.8 0.2 4e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_26 PF13659.1 CDO68211.1 - 1.7e-05 24.8 0.0 0.00072 19.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO68211.1 - 7.3e-05 23.3 0.0 0.00024 21.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO68211.1 - 0.00091 19.6 0.1 0.007 16.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain DUF2325 PF10087.4 CDO68211.1 - 0.0012 18.6 0.3 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2325) MTS PF05175.9 CDO68211.1 - 0.027 13.8 0.0 0.084 12.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain NAD_Gly3P_dh_N PF01210.18 CDO68211.1 - 0.042 13.5 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DREV PF05219.7 CDO68211.1 - 0.15 10.9 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase DUF43 PF01861.11 CDO68211.1 - 0.18 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Hydrophobin PF01185.13 CDO68212.1 - 1.2e-20 73.7 10.6 1.4e-20 73.4 7.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Phage_integrase PF00589.17 CDO68214.1 - 0.038 13.6 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family Hydrophobin PF01185.13 CDO68215.1 - 8.1e-19 67.8 9.2 1e-18 67.5 6.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Transposase_21 PF02992.9 CDO68218.1 - 2.3e-09 36.7 0.0 5.2e-09 35.5 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 CDO68218.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) G-alpha PF00503.15 CDO68221.1 - 4.1e-105 351.6 0.0 5.3e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CDO68221.1 - 6.2e-13 48.3 0.0 2.4e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 CDO68221.1 - 0.013 14.9 0.0 0.97 8.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pex16 PF08610.5 CDO68221.1 - 0.074 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) AAA_29 PF13555.1 CDO68221.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GMC_oxred_C PF05199.8 CDO68223.1 - 2.2e-09 37.7 0.0 7.3e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 CDO68223.1 - 0.0042 16.9 0.1 0.6 9.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 CDO68223.1 - 0.0082 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.12 CDO68223.1 - 0.076 12.1 0.3 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family VCBS PF13517.1 CDO68224.1 - 0.00022 21.5 7.1 0.0016 18.7 0.0 4.2 4 0 0 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CDO68224.1 - 0.0038 16.8 0.4 0.0038 16.8 0.3 2.6 3 0 0 3 3 3 1 FG-GAP repeat TcdB_toxin_midN PF12256.3 CDO68224.1 - 0.046 13.1 0.1 0.95 8.8 0.0 2.3 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region GMC_oxred_C PF05199.8 CDO68225.1 - 8.9e-07 29.2 0.2 7.5e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CDO68225.1 - 1.4e-06 27.7 0.0 2.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_3 PF01494.14 CDO68225.1 - 0.032 13.2 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Dimer_Tnp_hAT PF05699.9 CDO68226.1 - 2.6e-05 23.7 0.0 5.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.10 CDO68226.1 - 0.00019 20.9 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) TetR_C_7 PF14246.1 CDO68226.1 - 0.049 13.8 0.1 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal region Pho88 PF10032.4 CDO68227.1 - 1.4e-26 92.9 2.7 1.5e-26 92.8 1.8 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Macoilin PF09726.4 CDO68228.1 - 0.87 7.7 4.5 1 7.5 3.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DDE_1 PF03184.14 CDO68229.1 - 7.1e-26 90.6 0.0 1.2e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CDO68229.1 - 1.6e-08 34.1 0.2 3.6e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-CCCH PF00642.19 CDO68230.1 - 4.1e-14 51.8 15.5 4.1e-06 26.3 0.2 4.1 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CDO68230.1 - 0.00076 19.3 25.7 0.024 14.6 3.9 4.5 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type Gemini_AL2 PF01440.11 CDO68232.1 - 0.18 11.8 2.8 0.21 11.6 1.9 1.1 1 0 0 1 1 1 0 Geminivirus AL2 protein Abhydrolase_6 PF12697.2 CDO68233.1 - 0.011 15.6 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4218 PF13960.1 CDO68233.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) HNF-1A_C PF04813.7 CDO68234.1 - 0.027 14.7 0.3 0.064 13.5 0.2 1.6 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Pro_CA PF00484.14 CDO68234.1 - 0.058 13.3 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Carbonic anhydrase UBN2_3 PF14244.1 CDO68235.1 - 0.0039 16.7 0.6 0.52 9.8 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type Spc7 PF08317.6 CDO68235.1 - 0.022 13.4 2.7 0.043 12.4 1.0 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.7 CDO68235.1 - 0.026 14.3 0.4 0.67 9.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sec5 PF15469.1 CDO68235.1 - 0.034 13.8 2.5 0.23 11.1 0.9 2.2 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF1280 PF06918.9 CDO68235.1 - 0.057 12.6 1.6 0.089 11.9 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) CorA PF01544.13 CDO68235.1 - 0.24 10.3 2.6 0.22 10.5 0.9 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4559 PF15112.1 CDO68235.1 - 0.28 10.3 2.4 0.29 10.2 1.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) VPS11_C PF12451.3 CDO68235.1 - 3.5 7.5 8.0 3.8 7.4 0.0 3.5 3 1 1 4 4 4 0 Vacuolar protein sorting protein 11 C terminal Chromo PF00385.19 CDO68236.1 - 1.2e-08 34.4 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CDO68236.1 - 0.00015 21.8 0.1 0.00051 20.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Tudor-knot PF11717.3 CDO68236.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Exo_endo_phos_2 PF14529.1 CDO68238.1 - 6.7e-09 35.3 0.2 1.4e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CDO68238.1 - 3.5e-07 30.4 2.6 6.9e-07 29.4 1.8 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Prenyltrans PF00432.16 CDO68238.1 - 0.026 14.0 1.5 0.069 12.7 1.0 1.8 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat DUF77 PF01910.12 CDO68238.1 - 0.029 14.0 0.1 0.071 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF77 Ribosomal_L10 PF00466.15 CDO68241.1 - 1.1e-20 73.4 0.0 1.5e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DinI PF06183.8 CDO68241.1 - 0.011 15.7 0.2 0.018 15.0 0.2 1.3 1 0 0 1 1 1 0 DinI-like family HEAT_2 PF13646.1 CDO68242.1 - 6.5e-36 122.4 3.4 3.5e-15 56.0 0.1 4.2 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 CDO68242.1 - 3e-24 82.9 1.4 0.00058 20.0 0.0 7.3 8 0 0 8 8 8 4 PBS lyase HEAT-like repeat HEAT PF02985.17 CDO68242.1 - 1.2e-11 43.6 1.4 0.029 14.4 0.0 5.4 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 CDO68242.1 - 3.4e-10 40.0 3.0 0.0095 16.4 0.1 5.5 3 2 3 6 6 6 3 HEAT-like repeat Arm PF00514.18 CDO68242.1 - 0.00015 21.4 0.2 0.32 10.8 0.0 3.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Adaptin_binding PF10199.4 CDO68244.1 - 4.2e-10 40.0 1.9 8.6e-09 35.7 1.3 2.5 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Sporozoite_P67 PF05642.6 CDO68247.1 - 1.7 6.4 7.8 2 6.2 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.3 CDO68247.1 - 3.1 6.9 10.5 3.4 6.8 7.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PAT1 PF09770.4 CDO68247.1 - 3.6 5.7 11.8 4.1 5.5 8.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Methyltransf_18 PF12847.2 CDO68248.1 - 8.7e-09 35.9 0.0 2.4e-08 34.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO68248.1 - 1.6e-08 34.8 0.0 4.2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO68248.1 - 3.8e-07 30.1 0.0 1.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO68248.1 - 3.4e-06 26.7 0.0 6.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO68248.1 - 8.6e-06 26.1 0.0 3.1e-05 24.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO68248.1 - 6.5e-05 22.7 0.0 0.00017 21.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO68248.1 - 0.0026 18.1 0.0 0.009 16.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 CDO68248.1 - 0.0046 16.0 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 CDO68248.1 - 0.028 14.4 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Tricho_coat PF05892.6 CDO68248.1 - 0.057 12.6 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Trichovirus coat protein MTS PF05175.9 CDO68248.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CDC37_N PF03234.9 CDO68249.1 - 5.2e-46 157.1 8.3 5.2e-46 157.1 5.7 1.9 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 CDO68249.1 - 2.2e-31 108.6 0.0 5.7e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 CDO68249.1 - 5e-21 74.4 1.4 5e-21 74.4 1.0 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain DPBB_1 PF03330.13 CDO68250.1 - 1.1e-09 38.1 0.3 4.9e-09 36.0 0.2 1.9 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CDO68250.1 - 0.0037 16.9 0.2 0.0056 16.3 0.1 1.4 1 1 0 1 1 1 1 Barwin family zf-ribbon_3 PF13248.1 CDO68250.1 - 0.088 12.0 1.5 0.58 9.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain FANCL_C PF11793.3 CDO68250.1 - 0.12 12.3 0.9 5.6 7.0 0.0 2.7 1 1 2 3 3 3 0 FANCL C-terminal domain zf-TFIIB PF13453.1 CDO68250.1 - 0.22 10.7 0.9 9.8 5.4 0.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger His_Phos_1 PF00300.17 CDO68251.1 - 8.4e-17 61.7 0.0 1.9e-16 60.5 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4448 PF14610.1 CDO68253.1 - 0.0028 17.1 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 CDO68254.1 - 0.0005 20.4 0.6 0.00096 19.5 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4405 PF14358.1 CDO68254.1 - 0.056 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) DUF3088 PF11287.3 CDO68254.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) GST_N_3 PF13417.1 CDO68256.1 - 3.4e-12 46.4 0.0 2e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO68256.1 - 3.3e-10 39.9 0.0 2.3e-09 37.3 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO68256.1 - 2e-09 37.3 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CDO68256.1 - 2.2e-09 37.1 0.0 4.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO68256.1 - 1.5e-08 34.3 0.1 3.8e-08 33.0 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO68256.1 - 0.087 13.3 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MRP-L20 PF12824.2 CDO68258.1 - 1.4e-25 90.1 8.3 5.7e-25 88.1 5.8 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.1 CDO68258.1 - 0.05 14.4 0.2 0.05 14.4 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Sas10 PF09368.5 CDO68259.1 - 6.6e-24 83.8 7.7 6.6e-24 83.8 5.3 3.6 3 1 1 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CDO68259.1 - 2.1e-07 31.0 0.9 8.4e-07 29.0 0.6 2.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Zn_clus PF00172.13 CDO68260.1 - 2.2e-06 27.4 5.6 4e-06 26.6 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CDO68260.1 - 7.3e-06 25.0 0.0 5.9e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tom22 PF04281.8 CDO68261.1 - 1.6e-41 141.0 0.3 1.9e-41 140.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 NAD_binding_10 PF13460.1 CDO68262.1 - 1.7e-18 67.2 0.0 2.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CDO68262.1 - 1.7e-13 50.4 0.0 2.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CDO68262.1 - 1.2e-11 44.5 0.3 3.3e-10 39.7 0.2 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CDO68262.1 - 3.5e-11 42.5 0.0 1.5e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CDO68262.1 - 5.5e-10 38.4 0.1 3.5e-09 35.7 0.1 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CDO68262.1 - 1.3e-07 30.8 0.4 0.0072 15.2 0.1 3.4 1 1 1 2 2 2 2 Male sterility protein Saccharop_dh PF03435.13 CDO68262.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 CDO68262.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 CDO68262.1 - 0.021 14.7 0.1 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CDO68262.1 - 0.068 12.0 0.1 0.15 10.9 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 CDO68262.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF2462 PF09495.5 CDO68263.1 - 1.9e-19 70.1 12.0 1.9e-19 70.1 8.3 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) HTH_Tnp_Tc5 PF03221.11 CDO68264.1 - 1.7e-13 50.1 0.0 4.3e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.1 CDO68264.1 - 0.00021 20.8 0.0 0.0005 19.6 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_4 PF13613.1 CDO68264.1 - 0.00058 19.3 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 CDO68264.1 - 0.0013 18.3 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 MarR family CENP-B_N PF04218.8 CDO68264.1 - 0.0023 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_IclR PF09339.5 CDO68264.1 - 0.0027 17.2 0.0 0.09 12.3 0.0 2.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR PF01047.17 CDO68264.1 - 0.0033 17.0 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_31 PF13560.1 CDO68264.1 - 0.0075 16.4 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.1 CDO68264.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_38 PF13936.1 CDO68264.1 - 0.016 14.7 0.1 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.1 CDO68264.1 - 0.041 13.2 0.1 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.11 CDO68264.1 - 0.053 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 LacI PF00356.16 CDO68264.1 - 0.13 11.8 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_37 PF13744.1 CDO68264.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.17 CDO68264.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix CAF1 PF04857.15 CDO68265.1 - 6.6e-45 153.4 0.0 1.1e-44 152.7 0.0 1.4 1 1 0 1 1 1 1 CAF1 family ribonuclease SH3_9 PF14604.1 CDO68266.1 - 1.6e-19 69.1 1.7 6.6e-09 35.2 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CDO68266.1 - 4.5e-19 67.6 0.2 1.7e-08 33.8 0.2 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CDO68266.1 - 4.7e-16 57.8 1.0 2.6e-07 29.9 0.0 2.7 2 1 0 2 2 2 2 SH3 domain FCH PF00611.18 CDO68266.1 - 3e-08 33.7 0.3 3e-08 33.7 0.2 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.6 CDO68266.1 - 0.0055 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain DPBB_1 PF03330.13 CDO68267.1 - 2.2e-08 33.9 0.2 1.8e-07 31.0 0.0 2.1 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CDO68267.1 - 0.0094 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Barwin family Mannitol_dh_C PF08125.8 CDO68268.1 - 5.1e-56 189.5 0.0 1.2e-55 188.3 0.0 1.6 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 CDO68268.1 - 1.7e-25 89.7 0.0 3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 CDO68268.1 - 0.0093 15.6 0.1 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cullin PF00888.17 CDO68271.1 - 5.5e-191 636.1 16.7 8.5e-191 635.4 11.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CDO68271.1 - 1.5e-27 95.2 4.0 4.5e-27 93.6 2.8 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF1727 PF08353.5 CDO68271.1 - 0.0044 16.6 0.3 0.022 14.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1727) Rrf2 PF02082.15 CDO68271.1 - 0.061 13.4 0.1 0.32 11.1 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator Penicillinase_R PF03965.11 CDO68271.1 - 0.18 11.8 6.0 1.4 8.9 0.1 3.8 4 0 0 4 4 4 0 Penicillinase repressor KAT11 PF08214.6 CDO68273.1 - 3.3e-39 134.9 0.0 4.9e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Totivirus_coat PF05518.6 CDO68273.1 - 1 7.0 5.5 1.5 6.5 3.8 1.2 1 0 0 1 1 1 0 Totivirus coat protein DUF659 PF04937.10 CDO68274.1 - 1.8e-07 30.7 0.1 3.3e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) K_oxygenase PF13434.1 CDO68275.1 - 6.4e-46 156.8 0.0 9.1e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CDO68275.1 - 1.3e-06 28.4 0.0 1.8e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDO68275.1 - 7.1e-06 26.2 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CDO68275.1 - 0.0039 16.1 0.0 0.0053 15.7 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 CDO68275.1 - 0.011 13.9 0.0 0.015 13.5 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 CDO68275.1 - 0.038 12.8 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain gp12-short_mid PF09089.5 CDO68275.1 - 0.053 13.4 0.1 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Phage short tail fibre protein gp12, middle domain Pyr_redox PF00070.22 CDO68275.1 - 0.054 13.8 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO68275.1 - 0.14 11.9 0.1 8.2 6.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ribosomal_L24e PF01246.15 CDO68277.1 - 3.6e-30 103.6 3.7 3.6e-30 103.6 2.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.9 CDO68277.1 - 0.0025 17.4 5.2 0.0046 16.5 3.6 1.4 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif DUF581 PF04570.9 CDO68277.1 - 0.22 10.8 2.1 0.52 9.6 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF581) DUF2116 PF09889.4 CDO68277.1 - 0.29 10.9 3.5 0.31 10.8 0.6 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ATG_C PF09333.6 CDO68278.1 - 1.4e-34 118.1 0.1 3.4e-34 116.9 0.1 1.7 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 CDO68278.1 - 8.2e-12 44.7 0.0 1.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 CDO68278.1 - 1.8e-08 34.0 0.0 7.7e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif Apt1 PF10351.4 CDO68278.1 - 0.021 13.7 0.0 0.041 12.7 0.0 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain NatB_MDM20 PF09797.4 CDO68279.1 - 3e-67 226.9 0.2 5.4e-67 226.0 0.1 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit RPA_C PF08784.6 CDO68279.1 - 3.5e-12 46.6 0.0 8.6e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Replication protein A C terminal TPR_19 PF14559.1 CDO68279.1 - 1.3e-08 35.0 5.4 0.04 14.2 0.7 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CDO68279.1 - 1.8e-05 24.9 3.1 1.7 9.4 0.0 6.7 3 1 3 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.12 CDO68279.1 - 4.6e-05 23.7 1.3 0.00099 19.4 0.1 2.7 2 0 0 2 2 2 1 Bacterial transcriptional activator domain tRNA_anti-codon PF01336.20 CDO68279.1 - 0.00012 21.9 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain TPR_16 PF13432.1 CDO68279.1 - 0.00019 21.9 3.0 0.087 13.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDO68279.1 - 0.027 14.0 0.3 39 4.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 CDO68279.1 - 0.12 12.4 7.0 0.34 11.0 0.0 4.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 CDO68279.1 - 0.34 10.5 9.2 0.095 12.3 0.1 3.8 3 1 1 4 4 4 0 TPR repeat DUF2665 PF11654.3 CDO68280.1 - 2.6e-15 55.6 0.4 3.8e-15 55.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) Ribosomal_L30_N PF08079.7 CDO68281.1 - 1e-26 92.7 16.3 1e-26 92.7 11.3 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 CDO68281.1 - 9.9e-20 69.8 2.7 1.8e-19 69.0 1.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Consortin_C PF15281.1 CDO68281.1 - 0.26 10.7 1.3 0.41 10.1 0.9 1.3 1 0 0 1 1 1 0 Consortin C-terminus CLTH PF10607.4 CDO68283.1 - 8.7e-12 44.9 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CDO68283.1 - 0.0027 17.4 0.0 0.0056 16.3 0.0 1.6 1 0 0 1 1 1 1 LisH PQ-loop PF04193.9 CDO68284.1 - 1.6e-39 133.2 8.8 1.2e-19 69.6 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 CDO68284.1 - 0.092 12.6 1.8 0.097 12.5 0.2 1.8 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange AAA_12 PF13087.1 CDO68285.1 - 3.6e-47 160.3 0.0 6.1e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDO68285.1 - 7.1e-39 133.7 0.1 2e-34 119.2 0.1 2.4 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CDO68285.1 - 0.00052 19.6 0.0 0.039 13.4 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ICMT PF04140.9 CDO68286.1 - 2.5e-16 59.6 0.4 8.7e-14 51.4 0.1 2.5 1 1 1 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO68286.1 - 1.3e-10 41.2 1.9 2e-09 37.4 0.2 2.6 2 1 1 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO68286.1 - 4.3e-08 32.1 0.1 5.9e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 CDO68287.1 - 5.9e-14 52.0 0.1 1.5e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO68287.1 - 3.7e-10 39.8 0.4 1.3e-08 34.9 0.1 2.4 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO68287.1 - 8.8e-05 21.2 0.0 0.0004 19.0 0.0 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family GYF PF02213.11 CDO68288.1 - 2.5e-07 30.1 0.2 5.1e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 GYF domain SNF2_N PF00176.18 CDO68289.1 - 1.1e-58 198.4 0.1 3.3e-57 193.5 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 CDO68289.1 - 4e-40 137.6 10.8 7.4e-40 136.8 7.5 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 CDO68289.1 - 6.4e-14 51.5 0.0 1.5e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CDO68289.1 - 4.7e-10 38.7 0.0 1.5e-09 37.0 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 CDO68289.1 - 0.00021 21.4 0.1 0.0012 18.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 CDO68289.1 - 0.016 15.0 0.0 7.8 6.2 0.0 3.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit U1snRNP70_N PF12220.3 CDO68289.1 - 0.019 15.2 0.3 0.019 15.2 0.2 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Chromo PF00385.19 CDO68290.1 - 1.9e-10 40.2 0.7 3.4e-10 39.4 0.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain S-antigen PF05756.6 CDO68290.1 - 0.087 12.8 1.4 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 S-antigen protein DUF4537 PF15057.1 CDO68291.1 - 1.3e-08 34.6 0.4 3e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) BRCT PF00533.21 CDO68291.1 - 3.9e-06 26.9 0.0 0.00023 21.2 0.0 2.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain 53-BP1_Tudor PF09038.5 CDO68291.1 - 1.4e-05 24.8 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor DUF1325 PF07039.6 CDO68291.1 - 0.017 14.7 0.0 0.053 13.1 0.0 1.8 1 0 0 1 1 1 0 SGF29 tudor-like domain DUF4536 PF15055.1 CDO68292.1 - 0.028 14.4 0.5 0.21 11.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4536) Herpes_gE PF02480.11 CDO68292.1 - 0.035 12.3 3.4 1.9 6.6 2.1 2.2 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E MatE PF01554.13 CDO68292.1 - 0.05 13.2 0.4 0.11 12.0 0.3 1.5 1 0 0 1 1 1 0 MatE DUF3328 PF11807.3 CDO68292.1 - 0.54 9.9 2.0 1.4 8.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) Snf7 PF03357.16 CDO68293.1 - 4.8e-18 65.1 11.9 7.4e-18 64.5 8.3 1.2 1 0 0 1 1 1 1 Snf7 Phage_GP20 PF06810.6 CDO68293.1 - 0.0091 15.4 8.2 0.1 12.0 0.7 2.3 2 0 0 2 2 2 2 Phage minor structural protein GP20 AKNA PF12443.3 CDO68293.1 - 0.013 15.5 2.2 0.018 15.0 0.6 2.0 2 0 0 2 2 2 0 AT-hook-containing transcription factor Mnd1 PF03962.10 CDO68293.1 - 0.18 11.4 13.2 1.1 8.9 8.4 2.3 1 1 1 2 2 2 0 Mnd1 family NPV_P10 PF05531.7 CDO68293.1 - 1.6 9.0 4.6 0.67 10.2 0.4 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 CDO68293.1 - 2.1 8.3 11.3 1.2 9.1 3.0 2.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Aldo_ket_red PF00248.16 CDO68295.1 - 1.5e-35 122.4 0.0 2.5e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family TruB_N PF01509.13 CDO68295.1 - 3.5e-34 118.1 0.0 1.5e-33 116.0 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DHDPS PF00701.17 CDO68296.1 - 1.8e-29 102.2 0.0 8e-29 100.1 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family AlaDh_PNT_N PF05222.10 CDO68297.1 - 7.2e-45 152.3 0.2 9.5e-45 151.9 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB PF02233.11 CDO68298.1 - 9.3e-164 545.5 24.8 9.3e-164 545.5 17.2 1.9 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 CDO68298.1 - 1.2e-39 135.5 0.0 2.1e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF3814 PF12769.2 CDO68298.1 - 1e-32 112.1 4.9 1e-32 112.1 3.4 4.5 4 2 2 6 6 6 1 Domain of unknown function (DUF3814) Methyltransf_31 PF13847.1 CDO68298.1 - 0.13 11.8 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Nuc_sug_transp PF04142.10 CDO68299.1 - 1.8e-79 266.2 10.2 2.7e-79 265.6 7.0 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 CDO68299.1 - 1.8e-08 33.7 10.2 3.7e-08 32.6 7.1 1.4 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 CDO68299.1 - 4e-08 33.4 14.7 6.5e-08 32.7 0.4 2.8 2 0 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 CDO68299.1 - 1.8e-05 24.4 24.4 7e-05 22.5 2.8 2.8 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CDO68299.1 - 2.3e-05 24.4 21.7 4.1e-05 23.6 0.8 2.7 2 1 0 2 2 2 2 EamA-like transporter family OTU PF02338.14 CDO68300.1 - 8.2e-10 39.3 0.0 2.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Exo_endo_phos PF03372.18 CDO68300.1 - 3.4e-09 37.0 0.1 6.3e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CDO68300.1 - 0.012 15.2 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase ubiquitin PF00240.18 CDO68300.1 - 0.018 14.4 0.1 0.037 13.4 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin family Tom37_C PF11801.3 CDO68301.1 - 6.2e-14 52.2 0.0 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 CDO68301.1 - 1.6e-11 44.2 0.1 5.4e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 CDO68301.1 - 0.00015 21.5 0.1 0.00036 20.3 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TAFII55_N PF04658.8 CDO68302.1 - 5.1e-56 188.6 1.9 5.1e-56 188.6 1.3 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region Macoilin PF09726.4 CDO68302.1 - 0.16 10.2 2.7 0.29 9.3 1.9 1.4 1 0 0 1 1 1 0 Transmembrane protein Trep_dent_lipo PF09710.5 CDO68302.1 - 0.69 8.5 7.2 1.1 7.8 5.0 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) DUF506 PF04720.7 CDO68302.1 - 3.7 7.1 7.1 9.2 5.8 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Rep_4 PF05797.6 CDO68302.1 - 5.9 5.4 7.8 11 4.5 5.4 1.4 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Glucan_synthase PF02364.10 CDO68303.1 - 0 1364.5 0.0 0 1363.9 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Gaa1 PF04114.9 CDO68303.1 - 2.9e-60 204.4 3.6 2.9e-60 204.4 2.5 2.4 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component FKS1_dom1 PF14288.1 CDO68303.1 - 3.6e-39 133.2 0.0 8.9e-39 132.0 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SpoIIE PF07228.7 CDO68304.1 - 8.2e-14 51.7 0.0 2e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CDO68304.1 - 4.1e-05 23.0 0.0 5.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CDO68304.1 - 0.0023 17.3 0.1 0.026 13.9 0.0 2.1 1 1 1 2 2 2 1 Protein phosphatase 2C Ras PF00071.17 CDO68305.1 - 3.2e-50 169.6 0.0 3.8e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO68305.1 - 2.4e-16 60.3 0.0 4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO68305.1 - 4.3e-10 39.1 0.0 5.8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO68305.1 - 0.00027 20.1 0.0 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CDO68305.1 - 0.0016 17.1 2.0 1.2 7.7 0.1 2.9 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.17 CDO68305.1 - 0.014 15.5 0.1 0.12 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 CDO68305.1 - 0.027 13.7 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 CDO68305.1 - 0.038 14.1 0.1 0.11 12.5 0.0 1.7 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CDO68305.1 - 0.089 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain STAS PF01740.16 CDO68305.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 STAS domain GTP_EFTU PF00009.22 CDO68305.1 - 0.17 11.3 0.5 3.4 7.0 0.4 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MFS_1 PF07690.11 CDO68306.1 - 4.2e-46 157.2 42.3 8e-46 156.3 28.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO68306.1 - 3.5e-16 58.5 17.1 6.1e-16 57.7 11.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CDO68306.1 - 1.7e-11 43.4 16.0 1.7e-11 43.4 11.1 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Neurensin PF14927.1 CDO68306.1 - 0.16 11.3 2.5 0.26 10.6 0.1 2.5 3 0 0 3 3 3 0 Neurensin IncA PF04156.9 CDO68306.1 - 0.16 11.5 2.8 0.42 10.1 1.9 1.7 1 0 0 1 1 1 0 IncA protein DUF4231 PF14015.1 CDO68306.1 - 1.2 9.1 12.4 0.081 12.9 2.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Vac_ImportDeg PF09783.4 CDO68307.1 - 2.6e-47 160.5 0.0 3.2e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF605 PF04652.11 CDO68307.1 - 7.2 5.8 15.7 10 5.3 10.9 1.2 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 CDO68308.1 - 1.3e-36 126.0 0.0 1.5e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO68308.1 - 1.2e-13 50.7 0.0 1.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO68308.1 - 0.00077 19.2 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Phage_GP20 PF06810.6 CDO68309.1 - 0.012 15.0 5.2 0.024 14.0 3.6 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 GrpE PF01025.14 CDO68309.1 - 0.26 10.8 6.9 0.63 9.5 4.8 1.6 1 0 0 1 1 1 0 GrpE DUF342 PF03961.8 CDO68309.1 - 1.3 7.3 4.1 1.9 6.8 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 CDO68309.1 - 2.5 7.0 8.3 4.5 6.2 5.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CDO68309.1 - 2.6 7.6 9.7 0.079 12.5 2.4 1.7 2 0 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 CDO68309.1 - 6.1 4.5 4.0 9.9 3.8 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family JmjC PF02373.17 CDO68310.1 - 4.1e-09 36.6 0.1 1.9e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase DUF1465 PF07323.7 CDO68310.1 - 0.0097 15.4 0.2 0.29 10.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1465) GPI PF06560.6 CDO68310.1 - 0.067 12.2 0.0 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) AraC_binding PF02311.14 CDO68310.1 - 0.1 12.2 0.0 0.64 9.6 0.0 2.1 2 0 0 2 2 2 0 AraC-like ligand binding domain Cupin_2 PF07883.6 CDO68310.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Cupin domain DTW PF03942.10 CDO68310.1 - 0.77 8.9 3.7 5.7 6.0 0.0 2.5 2 1 0 2 2 2 0 DTW domain LEA_2 PF03168.8 CDO68311.1 - 1.5e-07 31.6 0.1 2.7e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.7 CDO68311.1 - 7.8e-05 21.9 0.2 0.00012 21.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Vac7 PF12751.2 CDO68311.1 - 0.0012 17.8 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF726 PF05277.7 CDO68312.1 - 8.4e-41 139.9 0.1 9.7e-41 139.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 CDO68312.1 - 0.0017 18.2 0.1 0.0018 18.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 CDO68312.1 - 0.022 14.4 0.0 0.038 13.7 0.0 1.5 1 1 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.2 CDO68312.1 - 0.027 14.2 0.0 0.036 13.8 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 CDO68312.1 - 0.032 13.7 0.1 0.07 12.6 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase DUF726 PF05277.7 CDO68313.1 - 2.8e-33 115.2 2.9 4.2e-33 114.6 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Spore_III_AB PF09548.5 CDO68313.1 - 0.033 13.9 0.1 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Gate PF07670.9 CDO68313.1 - 0.033 14.0 1.2 0.095 12.6 0.6 2.0 2 0 0 2 2 2 0 Nucleoside recognition Peptidase_M41 PF01434.13 CDO68314.1 - 9.4e-64 214.7 0.4 1.3e-37 129.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase family M41 AAA PF00004.24 CDO68314.1 - 4e-37 127.3 0.0 1.1e-36 125.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CDO68314.1 - 2.2e-05 25.2 0.0 0.0001 23.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CDO68314.1 - 0.00014 20.6 0.0 0.00024 19.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CDO68314.1 - 0.00019 20.5 0.0 0.00044 19.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CDO68314.1 - 0.00024 21.1 3.8 0.0044 17.0 0.1 3.5 3 2 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 CDO68314.1 - 0.00027 21.1 1.4 0.017 15.2 0.0 2.8 2 1 0 3 3 2 1 AAA domain AAA_5 PF07728.9 CDO68314.1 - 0.00028 20.6 0.1 0.0012 18.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CDO68314.1 - 0.00056 19.5 0.4 0.00056 19.5 0.2 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 CDO68314.1 - 0.0012 18.2 1.7 0.071 12.5 0.6 2.8 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CDO68314.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 CDO68314.1 - 0.0028 17.6 0.0 0.0093 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CDO68314.1 - 0.0034 17.2 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CDO68314.1 - 0.0042 16.2 0.2 0.01 15.0 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CDO68314.1 - 0.0044 16.9 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDO68314.1 - 0.0076 15.3 0.2 0.017 14.2 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 CDO68314.1 - 0.014 15.0 0.1 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 CDO68314.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CDO68314.1 - 0.029 14.6 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 CDO68314.1 - 0.04 12.8 0.0 0.09 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF3270 PF11674.3 CDO68314.1 - 5 7.1 7.2 39 4.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) DUF1227 PF06777.6 CDO68315.1 - 2.9e-58 195.7 0.3 7e-58 194.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 CDO68315.1 - 5.6e-43 146.3 0.1 9.9e-43 145.5 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CDO68315.1 - 4.3e-39 134.1 0.7 2e-38 131.9 0.0 2.3 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD PF00270.24 CDO68315.1 - 0.0005 19.6 0.1 0.083 12.3 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 CDO68315.1 - 0.0028 16.5 0.0 0.47 9.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.10 CDO68315.1 - 0.0054 16.5 1.6 0.041 13.6 0.1 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AOX PF01786.12 CDO68315.1 - 0.044 13.1 0.4 0.14 11.5 0.0 1.9 2 1 1 3 3 3 0 Alternative oxidase DUF2075 PF09848.4 CDO68315.1 - 0.052 12.5 0.4 5.8 5.7 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 CDO68315.1 - 0.073 12.6 0.2 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CDO68315.1 - 0.14 12.3 0.1 4.2 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.1 CDO68316.1 - 2.2e-08 33.9 5.6 0.016 15.1 0.1 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 CDO68316.1 - 0.0021 17.6 1.6 17 5.1 0.3 3.8 3 1 0 3 3 3 1 TPR repeat DUF2225 PF09986.4 CDO68316.1 - 0.0021 17.5 0.0 0.0066 15.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.12 CDO68316.1 - 0.0038 17.0 4.1 1.3 9.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CDO68316.1 - 0.0041 16.7 0.2 10 6.1 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO68316.1 - 0.0081 15.8 0.0 13 5.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CDO68316.1 - 0.0097 15.8 3.3 0.089 12.7 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDO68316.1 - 0.093 12.3 4.1 1.4 8.6 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat LUC7 PF03194.10 CDO68319.1 - 3.2e-71 239.8 4.1 4.1e-71 239.5 2.8 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Atg14 PF10186.4 CDO68319.1 - 0.0022 17.0 1.1 0.003 16.5 0.8 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Ada3 PF10198.4 CDO68319.1 - 0.014 15.1 0.9 0.026 14.2 0.6 1.5 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Mnd1 PF03962.10 CDO68319.1 - 0.074 12.7 2.0 0.14 11.8 1.4 1.4 1 0 0 1 1 1 0 Mnd1 family FliT PF05400.8 CDO68319.1 - 0.32 11.4 3.5 0.24 11.8 0.2 2.2 1 1 1 2 2 2 0 Flagellar protein FliT tRNA-synt_2 PF00152.15 CDO68321.1 - 8.5e-64 215.4 0.0 1.1e-33 116.4 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CDO68321.1 - 3.4e-10 39.6 0.0 5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DnaJ PF00226.26 CDO68322.1 - 3.8e-18 64.9 0.3 1.4e-17 63.1 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain Ank_2 PF12796.2 CDO68322.1 - 5.6e-09 36.2 0.0 1.8e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CDO68322.1 - 9.8e-08 31.5 0.0 7.5e-05 22.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CDO68322.1 - 6.5e-07 29.7 0.1 1.9e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CDO68322.1 - 3.4e-06 26.5 0.1 4.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CDO68322.1 - 5.9e-06 26.3 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Borrelia_P83 PF05262.6 CDO68322.1 - 0.39 8.9 11.9 0.56 8.4 8.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein BCS1_N PF08740.6 CDO68323.1 - 1.7e-45 154.9 0.1 2.3e-45 154.5 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CDO68323.1 - 1.3e-18 67.5 0.0 2.8e-18 66.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CDO68323.1 - 9.3e-07 29.6 0.0 3e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDO68323.1 - 0.0002 21.2 0.0 0.00039 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDO68323.1 - 0.00046 20.4 0.0 0.00099 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CDO68323.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDO68323.1 - 0.0011 19.0 0.1 0.0027 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 CDO68323.1 - 0.0025 16.8 0.0 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 CDO68323.1 - 0.0046 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CDO68323.1 - 0.0075 16.4 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO68323.1 - 0.0095 15.6 0.0 0.089 12.5 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 CDO68323.1 - 0.03 13.4 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 CDO68323.1 - 0.03 14.0 0.0 0.094 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CDO68323.1 - 0.031 14.5 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 CDO68323.1 - 0.032 14.3 0.0 0.078 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 CDO68323.1 - 0.056 12.5 0.0 0.52 9.3 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.1 CDO68323.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CDO68323.1 - 0.088 13.3 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Viral_helicase1 PF01443.13 CDO68323.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 CDO68323.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 CDO68323.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Methyltransf_11 PF08241.7 CDO68324.1 - 8.8e-10 38.9 0.0 2.4e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain WBS_methylT PF12589.3 CDO68324.1 - 8.5e-08 32.5 2.2 1.5e-07 31.7 1.5 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_23 PF13489.1 CDO68324.1 - 4.8e-07 29.6 0.0 7.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO68324.1 - 8e-06 26.2 0.3 2.5e-05 24.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO68324.1 - 2.9e-05 23.6 0.0 4.7e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO68324.1 - 0.00024 21.6 0.0 0.00045 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO68324.1 - 0.0024 18.2 0.0 0.0059 16.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain AdoMet_MTase PF07757.8 CDO68324.1 - 0.0039 17.2 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_26 PF13659.1 CDO68324.1 - 0.028 14.4 0.0 0.061 13.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain TRAPP PF04051.11 CDO68326.1 - 2.8e-37 127.5 0.0 4.1e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.5 CDO68326.1 - 0.05 13.4 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Ribosomal_S13 PF00416.17 CDO68327.1 - 4e-24 85.1 0.0 4.8e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CDO68327.1 - 0.0028 16.2 0.1 0.0052 15.3 0.0 1.6 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) XAP5 PF04921.9 CDO68328.1 - 3e-94 315.0 2.8 3e-94 315.0 2.0 2.6 1 1 1 2 2 2 1 XAP5, circadian clock regulator ATP-synt_D PF01813.12 CDO68329.1 - 1.3e-66 223.9 3.5 1.7e-66 223.5 2.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Iron_permease PF04120.7 CDO68329.1 - 1.3 8.5 3.8 2.5 7.6 0.5 2.1 2 0 0 2 2 2 0 Low affinity iron permease KOW PF00467.24 CDO68330.1 - 1.4e-09 37.3 3.5 1.4e-09 37.3 2.4 2.5 3 0 0 3 3 3 1 KOW motif FRG1 PF06229.7 CDO68331.1 - 4.7e-27 94.6 0.3 4.7e-27 94.6 0.2 1.5 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 CDO68331.1 - 0.0024 17.9 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Fascin domain DUF1754 PF08555.5 CDO68331.1 - 9.2 6.9 20.1 22 5.7 4.7 3.0 2 2 1 3 3 3 0 Eukaryotic family of unknown function (DUF1754) UCH PF00443.24 CDO68332.1 - 9.4e-32 110.1 3.9 9.9e-32 110.1 1.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDO68332.1 - 3.3e-20 72.7 2.6 6.4e-20 71.7 1.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CDO68332.1 - 6.5e-08 32.8 0.0 5.1e-05 23.5 0.0 3.0 2 0 0 2 2 2 2 DUSP domain ubiquitin PF00240.18 CDO68332.1 - 4.2e-07 29.2 0.1 9.1e-07 28.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family HNH_5 PF14279.1 CDO68332.1 - 0.31 11.0 2.0 6 6.9 0.0 3.9 5 0 0 5 5 5 0 HNH endonuclease RRN7 PF11781.3 CDO68332.1 - 3.5 7.1 5.1 18 4.9 0.0 3.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF1515 PF07439.6 CDO68334.1 - 0.14 11.9 1.9 5 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) RAI16-like PF10257.4 CDO68335.1 - 6.9e-72 242.3 0.0 1.1e-71 241.6 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein F-box PF00646.28 CDO68336.1 - 0.00038 20.0 0.1 0.0013 18.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain DnaJ PF00226.26 CDO68337.1 - 2.7e-22 78.2 2.6 2.7e-22 78.2 1.8 2.7 2 1 1 3 3 3 1 DnaJ domain Ribosomal_L1 PF00687.16 CDO68337.1 - 0.05 12.9 0.7 0.093 12.0 0.5 1.4 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family Seryl_tRNA_N PF02403.17 CDO68337.1 - 0.093 12.7 0.1 0.093 12.7 0.0 3.2 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3166 PF11365.3 CDO68337.1 - 3.1 8.3 15.0 0.13 12.7 1.3 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3166) DUF575 PF04746.7 CDO68339.1 - 0.078 13.0 2.0 13 5.9 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF575) SET PF00856.23 CDO68340.1 - 0.0016 18.8 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 SET domain adh_short PF00106.20 CDO68341.1 - 6e-33 114.1 1.4 7.7e-33 113.7 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO68341.1 - 7.7e-15 55.3 0.1 1e-14 54.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO68341.1 - 1.8e-12 47.3 0.3 2.3e-12 46.9 0.2 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CDO68341.1 - 0.00013 21.7 1.9 0.00032 20.4 1.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CDO68341.1 - 0.0015 18.0 0.1 0.0023 17.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Helicase_RecD PF05127.9 CDO68341.1 - 0.0015 18.1 0.1 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Helicase THF_DHG_CYH_C PF02882.14 CDO68341.1 - 0.016 14.2 0.1 0.047 12.7 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 CDO68341.1 - 0.023 14.7 1.1 0.044 13.8 0.6 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CDO68341.1 - 0.097 12.3 1.3 0.098 12.3 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.13 CDO68343.1 - 0.00035 20.4 0.9 0.00035 20.4 0.6 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_rhodopsin PF01036.13 CDO68344.1 - 1.4e-44 152.0 20.2 1.9e-44 151.6 14.0 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein CcoS PF03597.10 CDO68344.1 - 0.035 13.5 0.5 0.17 11.4 0.3 2.2 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Aldo_ket_red PF00248.16 CDO68345.1 - 5.2e-50 169.8 0.0 5.8e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OTU PF02338.14 CDO68346.1 - 7.6e-19 68.4 0.0 1.7e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CDO68346.1 - 0.0072 15.7 0.0 0.8 9.0 0.0 2.5 1 1 1 2 2 2 2 Peptidase C65 Otubain HEAT_2 PF13646.1 CDO68346.1 - 0.062 13.5 3.9 0.057 13.7 1.2 2.0 1 1 0 2 2 2 0 HEAT repeats DUF2413 PF10310.4 CDO68346.1 - 5.3 5.7 7.2 7.3 5.2 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Adaptin_N PF01602.15 CDO68347.1 - 1.6e-123 412.8 6.1 5.2e-122 407.8 4.2 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CDO68347.1 - 1.2e-23 83.8 2.9 1.2e-20 74.1 0.2 3.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CDO68347.1 - 1.1e-16 60.8 11.4 1.2e-10 41.5 0.4 5.2 2 2 4 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 CDO68347.1 - 4.3e-09 36.5 2.6 1.3 9.5 0.0 6.5 6 1 1 7 7 7 3 HEAT-like repeat HEAT PF02985.17 CDO68347.1 - 5.9e-09 35.2 9.6 0.0076 16.2 0.0 6.0 8 0 0 8 8 8 3 HEAT repeat Arm PF00514.18 CDO68347.1 - 5.6e-06 25.9 4.6 0.18 11.7 0.0 5.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 CDO68347.1 - 0.00012 21.4 0.1 0.0061 15.9 0.0 3.0 3 0 0 3 3 3 1 CLASP N terminal RasGEF_N_2 PF14663.1 CDO68347.1 - 0.039 13.9 0.2 31 4.5 0.0 3.7 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_PBS PF03130.11 CDO68347.1 - 0.089 13.3 1.8 36 5.2 0.1 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Pyr_redox_2 PF07992.9 CDO68349.1 - 1.1e-08 35.2 0.0 1.3e-07 31.7 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO68349.1 - 0.0024 17.6 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CDO68349.1 - 0.0096 16.0 0.4 5 7.1 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 CDO68349.1 - 0.077 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain DAO PF01266.19 CDO68349.1 - 0.16 10.8 0.4 11 4.8 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Flg_bb_rod PF00460.15 CDO68350.1 - 0.13 12.0 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 Flagella basal body rod protein Cu_bind_like PF02298.12 CDO68351.1 - 4.4e-05 23.1 0.3 0.0001 22.0 0.2 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.15 CDO68351.1 - 0.02 15.1 0.4 0.063 13.5 0.3 1.8 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Methyltransf_3 PF01596.12 CDO68352.1 - 3.7e-36 124.1 0.0 3.5e-24 84.9 0.0 3.0 3 0 0 3 3 3 3 O-methyltransferase Methyltransf_24 PF13578.1 CDO68352.1 - 2.3e-12 47.6 0.0 5.3e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CDO68352.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 CDO68352.1 - 0.12 13.0 0.0 0.41 11.2 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain MSC PF09402.5 CDO68353.1 - 3e-54 183.9 0.0 1.1e-53 182.1 0.0 2.0 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 CDO68353.1 - 3.8e-11 42.3 0.0 7.6e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain UEV PF05743.8 CDO68354.1 - 3.3e-34 117.1 0.0 4.9e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 CDO68354.1 - 6.1e-18 64.1 0.8 1.4e-17 63.0 0.1 1.9 2 0 0 2 2 2 1 Vps23 core domain RNA_pol_Rpc34 PF05158.7 CDO68355.1 - 1.7e-76 257.4 0.4 8e-67 225.7 0.3 2.1 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit Hex_IIIa PF02455.11 CDO68355.1 - 1.8 7.1 5.5 2.6 6.6 3.8 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Gag_spuma PF03276.9 CDO68355.1 - 2.1 6.5 7.2 3.1 6.0 5.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Nucleo_P87 PF07267.6 CDO68355.1 - 3.8 6.0 13.4 6.4 5.3 9.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 p450 PF00067.17 CDO68357.1 - 8.8e-52 176.1 0.0 1.1e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MKT1_C PF12246.3 CDO68358.1 - 4.6e-52 176.4 0.0 6.6e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CDO68358.1 - 1.5e-27 95.6 0.0 3.3e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 CDO68358.1 - 8.6e-10 38.5 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CDO68358.1 - 9.7e-08 32.2 0.0 2.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DNA_ligase_A_M PF01068.16 CDO68359.1 - 9.4e-24 83.9 0.0 2.4e-23 82.5 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CDO68359.1 - 1.2e-14 54.5 0.0 2.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus Pirin PF02678.11 CDO68360.1 - 9.8e-25 86.5 5.1 8.5e-24 83.4 3.5 2.1 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 CDO68360.1 - 4.3e-09 35.7 2.4 4.5e-07 29.2 0.9 2.4 2 0 0 2 2 2 2 Cupin domain WD40 PF00400.27 CDO68361.1 - 1.1e-46 155.1 17.9 3.5e-13 48.8 0.5 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat NLE PF08154.7 CDO68361.1 - 2e-09 37.2 0.0 3.6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CDO68361.1 - 9.3e-06 24.0 3.1 0.0034 15.5 0.0 3.3 3 1 0 4 4 4 2 Nucleoporin Nup120/160 HAUS6_N PF14661.1 CDO68363.1 - 7.3e-10 38.6 10.5 5.1e-07 29.2 0.1 4.0 4 0 0 4 4 4 3 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_L37e PF01907.14 CDO68364.1 - 3.9e-08 32.9 2.4 1e-07 31.6 1.5 1.8 1 1 0 1 1 1 1 Ribosomal protein L37e MIP-T3 PF10243.4 CDO68365.1 - 1.4 7.2 25.3 1.6 7.1 17.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pex14_N PF04695.8 CDO68365.1 - 2.3 8.2 15.1 0.28 11.2 5.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4551 PF15087.1 CDO68365.1 - 3.1 6.0 8.9 3.7 5.7 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ebola_NP PF05505.7 CDO68365.1 - 3.7 5.4 10.9 4.4 5.2 7.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Opi1 PF08618.5 CDO68366.1 - 5.6e-21 74.9 14.5 6.3e-19 68.1 10.1 2.1 1 1 0 1 1 1 1 Transcription factor Opi1 Perilipin PF03036.11 CDO68366.1 - 3e-05 23.0 1.4 3.3e-05 22.9 0.0 1.7 3 0 0 3 3 3 1 Perilipin family MYT1 PF08474.6 CDO68367.1 - 2.3 7.6 8.8 0.027 13.9 0.6 1.8 2 1 0 2 2 2 0 Myelin transcription factor 1 AATase PF07247.7 CDO68369.1 - 5.2e-17 61.5 0.0 3.3e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase DPBB_1 PF03330.13 CDO68369.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Condensation PF00668.15 CDO68369.1 - 0.02 13.7 0.2 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Condensation domain Aminotran_3 PF00202.16 CDO68370.1 - 3.1e-74 249.8 0.1 4.1e-74 249.4 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CDO68370.1 - 0.042 12.8 0.0 0.078 11.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II HrpE PF06188.7 CDO68370.1 - 0.15 11.8 0.0 0.7 9.6 0.0 2.0 3 0 0 3 3 3 0 HrpE/YscL/FliH and V-type ATPase subunit E HAD_2 PF13419.1 CDO68371.1 - 1.2e-25 90.7 0.2 4.1e-24 85.7 0.1 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDO68371.1 - 2.6e-06 28.0 0.0 4.2e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CDO68371.1 - 0.0014 18.2 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like AAA PF00004.24 CDO68372.1 - 2.3e-42 144.3 0.1 6.4e-42 142.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DRMBL PF07522.9 CDO68372.1 - 4.8e-28 97.3 0.0 1.3e-27 96.0 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CDO68372.1 - 1e-10 41.5 0.0 2.3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AAA_5 PF07728.9 CDO68372.1 - 1.9e-06 27.6 0.2 1.2e-05 25.1 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDO68372.1 - 4.8e-06 26.6 0.0 8.1e-05 22.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CDO68372.1 - 2.4e-05 24.3 0.0 8.3e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CDO68372.1 - 3.1e-05 24.7 0.0 0.0048 17.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CDO68372.1 - 3.5e-05 22.9 0.0 8.4e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CDO68372.1 - 7.5e-05 22.8 0.0 0.003 17.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO68372.1 - 0.0001 21.9 0.1 0.00063 19.4 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 CDO68372.1 - 0.0045 15.7 0.2 0.017 13.8 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 CDO68372.1 - 0.0048 15.8 0.0 0.0097 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 CDO68372.1 - 0.006 16.7 0.0 0.035 14.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 CDO68372.1 - 0.0086 15.5 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CDO68372.1 - 0.0095 15.1 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CDO68372.1 - 0.012 15.4 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CDO68372.1 - 0.015 15.6 0.0 0.11 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CDO68372.1 - 0.017 15.0 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CDO68372.1 - 0.024 14.5 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CDO68372.1 - 0.03 13.9 0.0 0.093 12.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4200 PF13863.1 CDO68372.1 - 0.033 14.1 2.4 0.071 13.0 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) UPF0079 PF02367.12 CDO68372.1 - 0.033 13.8 0.0 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 CDO68372.1 - 0.035 13.1 0.8 0.055 12.5 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin AAA_24 PF13479.1 CDO68372.1 - 0.038 13.5 0.1 0.083 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CDO68372.1 - 0.041 13.1 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Lactamase_B PF00753.22 CDO68372.1 - 0.044 13.4 0.3 0.1 12.2 0.2 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Sigma54_activat PF00158.21 CDO68372.1 - 0.048 13.1 0.2 0.23 10.9 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 CDO68372.1 - 0.052 12.9 0.2 0.17 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF3450 PF11932.3 CDO68372.1 - 0.067 12.4 0.5 0.12 11.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.7 CDO68372.1 - 0.072 12.8 2.6 0.16 11.7 1.8 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_11 PF13086.1 CDO68372.1 - 0.074 12.6 0.6 2.3 7.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain ResIII PF04851.10 CDO68372.1 - 0.076 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CDO68372.1 - 0.11 12.8 0.0 23 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 CDO68372.1 - 0.12 11.2 0.1 0.41 9.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF659 PF04937.10 CDO68373.1 - 5.8e-07 29.1 0.2 1.1e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.9 CDO68373.1 - 0.00046 19.7 0.7 0.0049 16.4 0.0 2.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Ribosomal_S4e PF00900.15 CDO68374.1 - 2.5e-31 107.1 0.3 5.1e-31 106.1 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 CDO68374.1 - 1.9e-21 75.5 3.4 1.1e-20 73.1 2.8 1.9 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 CDO68374.1 - 4e-07 29.3 0.0 1.2e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CDO68374.1 - 0.00066 19.2 2.4 0.0022 17.6 1.7 2.0 1 0 0 1 1 1 1 KOW motif GCFC PF07842.7 CDO68375.1 - 1.9e-82 276.7 6.9 3.4e-82 275.9 4.8 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 CDO68375.1 - 1.3e-14 54.1 10.2 1.3e-14 54.1 7.1 3.2 2 1 2 4 4 4 1 Tuftelin interacting protein N terminal G-patch PF01585.18 CDO68375.1 - 2.1e-12 46.6 2.8 2.1e-12 46.6 2.0 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CDO68375.1 - 3.5e-09 36.3 4.8 2.8e-07 30.2 1.0 3.1 2 0 0 2 2 2 2 DExH-box splicing factor binding site IncA PF04156.9 CDO68375.1 - 0.027 14.0 0.4 0.059 12.9 0.3 1.5 1 0 0 1 1 1 0 IncA protein HECT PF00632.20 CDO68376.1 - 4.7e-83 278.9 0.0 6.7e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 CDO68376.1 - 0.55 10.1 4.0 2.1 8.2 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat FAD_binding_3 PF01494.14 CDO68377.1 - 9.5e-87 291.3 0.0 1.3e-86 290.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 CDO68377.1 - 5.9e-28 97.5 0.1 9.8e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 CDO68377.1 - 3.5e-06 25.7 1.2 5.2e-06 25.1 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 CDO68377.1 - 2.7e-05 24.1 0.0 5.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO68377.1 - 6.2e-05 23.3 0.3 0.005 17.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDO68377.1 - 6.3e-05 22.1 0.2 0.00012 21.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CDO68377.1 - 6.7e-05 21.9 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDO68377.1 - 0.0001 22.2 0.1 0.00033 20.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CDO68377.1 - 0.00011 21.2 2.6 0.00016 20.6 1.4 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 CDO68377.1 - 0.00015 21.0 0.1 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CDO68377.1 - 0.0011 17.9 1.4 0.0017 17.3 1.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 CDO68377.1 - 0.0018 17.2 0.8 0.0031 16.4 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 CDO68377.1 - 0.0035 16.0 0.1 0.0059 15.2 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase ThiF PF00899.16 CDO68377.1 - 0.0045 16.8 0.2 0.0088 15.8 0.1 1.5 1 0 0 1 1 1 1 ThiF family 3HCDH_N PF02737.13 CDO68377.1 - 0.011 15.4 0.4 0.019 14.6 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 CDO68377.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 CDO68377.1 - 0.017 15.1 0.2 0.036 14.1 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO68377.1 - 0.027 14.2 0.2 0.057 13.1 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.1 CDO68377.1 - 0.028 14.7 0.1 0.084 13.1 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain ApbA PF02558.11 CDO68377.1 - 0.035 13.5 0.1 0.069 12.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 CDO68377.1 - 0.069 12.7 0.4 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UCH PF00443.24 CDO68378.1 - 2.8e-73 246.3 0.0 1.1e-72 244.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDO68378.1 - 1.6e-25 90.1 0.0 2.3e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MIZ PF02891.15 CDO68378.1 - 0.0047 16.4 0.3 0.011 15.2 0.2 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Rhodanese PF00581.15 CDO68378.1 - 0.0069 16.7 0.0 0.021 15.1 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.6 CDO68378.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain MIT PF04212.13 CDO68378.1 - 0.15 11.9 0.1 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain zf-HC5HC2H_2 PF13832.1 CDO68379.1 - 1.4e-20 73.3 20.1 2.8e-20 72.3 1.7 4.4 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CDO68379.1 - 6.4e-16 58.2 1.6 6.4e-16 58.2 1.1 4.5 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.24 CDO68379.1 - 1.4e-13 50.3 61.5 4.7e-09 35.7 6.5 6.1 6 1 0 6 6 6 3 PHD-finger BAH PF01426.13 CDO68379.1 - 1.4e-10 40.9 0.0 4.4e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 BAH domain GATA PF00320.22 CDO68379.1 - 0.00015 20.9 3.3 0.00015 20.9 2.3 3.7 3 0 0 3 3 3 1 GATA zinc finger Myb_DNA-binding PF00249.26 CDO68379.1 - 0.00078 19.4 0.0 0.0022 17.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain PHD_2 PF13831.1 CDO68379.1 - 0.00083 18.6 2.9 0.00083 18.6 2.0 6.8 8 0 0 8 8 8 4 PHD-finger Prok-RING_1 PF14446.1 CDO68379.1 - 0.0028 17.3 4.1 0.0028 17.3 2.9 5.0 6 0 0 6 6 6 2 Prokaryotic RING finger family 1 ELM2 PF01448.19 CDO68379.1 - 0.019 15.5 0.0 0.06 14.0 0.0 1.9 1 0 0 1 1 1 0 ELM2 domain Aldo_ket_red PF00248.16 CDO68380.1 - 2.3e-10 39.7 0.0 1.2e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Aldo/keto reductase family Epimerase PF01370.16 CDO68381.1 - 1.6e-20 73.5 0.0 2.3e-17 63.2 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO68381.1 - 8.5e-13 47.6 0.0 3.1e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CDO68381.1 - 1.1e-08 35.2 0.0 2.6e-08 34.1 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CDO68381.1 - 2e-05 23.6 0.3 4e-05 22.6 0.2 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CDO68381.1 - 0.00018 21.4 0.4 0.00036 20.4 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 CDO68381.1 - 0.0014 17.9 0.5 0.0031 16.8 0.3 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 CDO68381.1 - 0.0078 15.1 1.4 0.13 11.1 1.0 2.1 1 1 0 1 1 1 1 Male sterility protein p450 PF00067.17 CDO68382.1 - 8.8e-60 202.5 0.0 9.7e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PHF5 PF03660.9 CDO68383.1 - 5.6e-51 171.1 8.0 6.2e-51 170.9 5.5 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 CDO68383.1 - 0.27 11.0 14.7 0.047 13.5 4.6 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 CDO68383.1 - 0.43 10.3 14.3 2.3 7.9 0.3 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 CDO68383.1 - 1.3 8.7 14.1 0.034 13.8 3.7 2.5 1 1 1 2 2 2 0 PHD-finger PolC_DP2 PF03833.8 CDO68383.1 - 6.6 4.2 6.4 7.2 4.1 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.7 CDO68383.1 - 9.6 6.0 13.0 10 5.9 4.9 2.7 1 1 0 1 1 1 0 zinc-ribbons ADH_N PF08240.7 CDO68384.1 - 1e-16 60.6 3.3 4.4e-16 58.5 0.5 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO68384.1 - 3.1e-08 33.2 0.1 3.1e-08 33.2 0.1 2.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CDO68384.1 - 0.0063 16.0 0.3 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Ubie_methyltran PF01209.13 CDO68384.1 - 0.015 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CDO68384.1 - 0.023 15.2 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CDO68384.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.14 CDO68385.1 - 4e-80 269.5 0.3 4.9e-80 269.2 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 CDO68385.1 - 1.2e-26 93.3 0.0 2.1e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 CDO68385.1 - 3.4e-05 22.4 0.9 5.5e-05 21.8 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 CDO68385.1 - 0.00022 20.3 0.2 0.00045 19.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CDO68385.1 - 0.00049 20.0 0.2 0.0015 18.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDO68385.1 - 0.0005 19.9 0.1 0.00093 19.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CDO68385.1 - 0.00093 18.2 3.1 0.025 13.5 0.6 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 CDO68385.1 - 0.0017 17.3 2.5 0.0049 15.8 1.1 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CDO68385.1 - 0.0019 17.3 2.6 0.0036 16.4 1.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDO68385.1 - 0.0026 16.6 9.2 0.0033 16.3 1.9 2.1 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CDO68385.1 - 0.0035 17.7 0.3 0.03 14.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDO68385.1 - 0.0086 16.1 0.3 0.017 15.1 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CDO68385.1 - 0.018 13.6 0.1 0.028 13.0 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 CDO68385.1 - 0.023 14.3 0.1 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 CDO68385.1 - 0.037 13.8 0.2 0.076 12.7 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 CDO68385.1 - 0.053 12.3 1.7 0.084 11.7 1.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.16 CDO68385.1 - 0.098 12.4 0.4 0.17 11.6 0.3 1.4 1 0 0 1 1 1 0 ThiF family ADIP PF11559.3 CDO68386.1 - 3.5e-19 69.2 10.2 3.5e-19 69.2 7.1 3.1 3 1 1 4 4 4 2 Afadin- and alpha -actinin-Binding CASP_C PF08172.7 CDO68386.1 - 1.3e-05 24.3 1.5 1.3e-05 24.3 1.0 2.4 3 1 0 3 3 3 1 CASP C terminal EF-hand_like PF09279.6 CDO68386.1 - 0.071 13.1 0.1 0.33 10.9 0.1 2.1 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like CCDC144C PF14915.1 CDO68386.1 - 0.16 10.8 24.3 0.05 12.5 8.4 2.3 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DUF3138 PF11336.3 CDO68386.1 - 0.82 7.7 5.4 1.8 6.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) OmpH PF03938.9 CDO68386.1 - 0.96 9.3 24.3 3.7 7.4 8.6 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) IncA PF04156.9 CDO68386.1 - 1.8 8.1 33.3 0.22 11.0 7.3 2.6 2 1 1 3 3 3 0 IncA protein Oxidored_molyb PF00174.14 CDO68387.1 - 1.1e-39 135.5 0.0 1.7e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CDO68387.1 - 5.3e-28 97.2 0.3 9.9e-28 96.3 0.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 CDO68387.1 - 2.9e-18 65.8 0.0 5.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CDO68387.1 - 1.5e-11 44.7 0.0 3.6e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 CDO68387.1 - 2.9e-08 33.3 0.0 7.6e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HATPase_c PF02518.21 CDO68388.1 - 8.1e-24 83.4 1.1 2.6e-23 81.8 0.7 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CDO68388.1 - 2.6e-16 59.6 0.0 6.2e-15 55.1 0.0 2.5 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 CDO68388.1 - 0.02 14.8 0.0 0.051 13.5 0.0 1.8 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 CDO68388.1 - 0.1 12.2 0.0 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAD_binding_3 PF01494.14 CDO68389.1 - 3.8e-45 154.4 0.3 4.8e-16 58.7 0.0 3.2 1 1 2 3 3 3 3 FAD binding domain Phe_hydrox_dim PF07976.7 CDO68389.1 - 3.3e-22 78.8 0.0 1.7e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 CDO68389.1 - 2.8e-07 29.3 0.5 4e-07 28.8 0.3 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 CDO68389.1 - 1.5e-06 27.3 0.1 2.2e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CDO68389.1 - 2.2e-05 24.4 0.2 3.7e-05 23.7 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO68389.1 - 9.3e-05 22.3 0.0 0.00027 20.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CDO68389.1 - 9.9e-05 21.5 0.1 0.0002 20.5 0.1 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CDO68389.1 - 0.0002 20.3 0.1 0.00054 18.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CDO68389.1 - 0.00044 19.2 0.4 0.00066 18.7 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 CDO68389.1 - 0.0023 16.8 0.1 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 CDO68389.1 - 0.0038 17.6 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDO68389.1 - 0.0085 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO68389.1 - 0.0089 15.8 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 CDO68389.1 - 0.0091 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 CDO68389.1 - 0.015 14.4 0.4 0.024 13.7 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CDO68389.1 - 0.054 13.0 0.1 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 CDO68389.1 - 0.061 11.9 0.1 0.087 11.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 CDO68389.1 - 0.073 13.0 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.16 CDO68389.1 - 0.18 11.6 0.1 0.39 10.5 0.1 1.6 1 0 0 1 1 1 0 ThiF family Paf1 PF03985.8 CDO68390.1 - 7.4e-58 196.3 0.0 9.1e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Paf1 CENP-X PF09415.5 CDO68391.1 - 0.084 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X APH PF01636.18 CDO68393.1 - 2.1e-13 50.5 0.1 2.1e-13 50.5 0.1 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family F-box-like PF12937.2 CDO68393.1 - 3.5e-09 36.2 1.6 9e-09 34.9 1.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 CDO68393.1 - 0.00042 19.8 0.9 0.54 9.9 0.0 4.4 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) RIO1 PF01163.17 CDO68393.1 - 0.00044 19.6 0.0 0.88 8.8 0.0 3.3 3 0 0 3 3 3 2 RIO1 family LRR_8 PF13855.1 CDO68393.1 - 0.0006 19.5 0.1 1.5 8.5 0.1 3.3 3 0 0 3 3 3 2 Leucine rich repeat Choline_kinase PF01633.15 CDO68393.1 - 0.0016 18.0 0.0 0.0045 16.5 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase F-box PF00646.28 CDO68393.1 - 0.015 14.9 3.7 0.23 11.1 0.4 3.1 2 0 0 2 2 2 0 F-box domain Pkinase_Tyr PF07714.12 CDO68393.1 - 0.083 11.9 0.0 0.29 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase EcKinase PF02958.15 CDO68393.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase LRR_7 PF13504.1 CDO68393.1 - 0.25 11.7 2.2 13 6.5 0.0 4.4 4 1 1 5 5 5 0 Leucine rich repeat Fructosamin_kin PF03881.9 CDO68393.1 - 0.28 10.1 0.0 7.5 5.4 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Evr1_Alr PF04777.8 CDO68394.1 - 2.1e-30 104.4 0.6 5.3e-30 103.1 0.1 1.8 2 0 0 2 2 2 1 Erv1 / Alr family TFIIA PF03153.8 CDO68394.1 - 0.078 12.8 1.3 0.07 13.0 0.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_47 PF01532.15 CDO68395.1 - 1.1e-132 442.9 0.0 1.2e-132 442.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_S28 PF05577.7 CDO68396.1 - 4.1e-57 193.7 0.6 3.3e-56 190.6 0.4 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase S28 WD40 PF00400.27 CDO68396.1 - 2.3e-07 30.4 2.4 0.056 13.3 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat CRAL_TRIO PF00650.15 CDO68397.1 - 2.1e-29 102.0 0.0 3.4e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CDO68397.1 - 1.9e-05 24.6 0.0 4.9e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain HABP4_PAI-RBP1 PF04774.10 CDO68397.1 - 0.63 10.5 5.0 1.5 9.3 3.4 1.7 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Histone PF00125.19 CDO68398.1 - 5.9e-30 103.2 0.7 9.4e-30 102.5 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CDO68398.1 - 2.3e-05 24.4 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CDO68398.1 - 0.0027 17.7 0.1 0.0055 16.7 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CDO68398.1 - 0.011 15.0 1.7 0.012 14.8 1.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CDO68398.1 - 0.081 12.6 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CDO68399.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CDO68399.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CDO68399.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CDO68399.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CDO68399.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CDO68399.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit F-box-like PF12937.2 CDO68400.1 - 7.2e-08 32.0 0.1 1.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO68400.1 - 0.00029 20.4 0.2 0.0012 18.4 0.0 2.2 2 0 0 2 2 2 1 F-box domain RhoGAP PF00620.22 CDO68401.1 - 6.1e-48 162.2 0.0 1.2e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 CDO68401.1 - 2.7e-14 53.1 3.0 2.9e-13 49.8 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PA26 PF04636.8 CDO68401.1 - 0.11 11.1 2.2 1.8 7.1 2.7 1.8 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) CorA PF01544.13 CDO68401.1 - 0.71 8.8 3.9 0.75 8.7 1.7 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DivIC PF04977.10 CDO68401.1 - 1.9 8.0 8.4 0.15 11.5 1.9 2.1 3 0 0 3 3 3 0 Septum formation initiator Zip PF02535.17 CDO68402.1 - 8.8e-56 189.2 7.7 1.1e-55 188.9 5.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter CHRD PF07452.7 CDO68403.1 - 0.00035 21.1 0.1 0.00061 20.3 0.1 1.5 1 1 0 1 1 1 1 CHRD domain DEAD PF00270.24 CDO68404.1 - 1.1e-39 135.6 0.1 1.7e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO68404.1 - 6.3e-21 74.0 0.1 4.1e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CDO68404.1 - 0.0001 22.1 0.1 0.00081 19.2 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PNMA PF14893.1 CDO68404.1 - 0.089 11.8 0.1 0.17 10.8 0.1 1.4 1 0 0 1 1 1 0 PNMA Pkinase PF00069.20 CDO68405.1 - 7.2e-10 38.4 0.0 1.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO68405.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Dynactin_p22 PF07426.6 CDO68407.1 - 0.019 14.2 1.0 5 6.3 0.0 2.8 2 1 1 3 3 3 0 Dynactin subunit p22 MscS_porin PF12795.2 CDO68407.1 - 0.033 13.5 1.4 0.11 11.8 1.0 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain V_ATPase_I PF01496.14 CDO68407.1 - 0.046 11.5 0.5 0.061 11.1 0.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Nif11 PF07862.6 CDO68407.1 - 0.28 11.1 2.4 1.4 8.9 0.3 2.8 2 1 1 3 3 3 0 Nitrogen fixation protein of unknown function DUF3829 PF12889.2 CDO68407.1 - 0.37 9.9 3.3 2.4 7.2 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3829) Lebercilin PF15619.1 CDO68407.1 - 0.59 9.5 8.9 0.45 9.9 1.1 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF848 PF05852.6 CDO68407.1 - 1.5 8.6 5.1 2.9 7.7 0.0 2.8 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Cortex-I_coil PF09304.5 CDO68407.1 - 3 7.9 7.9 2 8.5 0.6 2.9 2 1 1 3 3 3 0 Cortexillin I, coiled coil SHNi-TPR PF10516.4 CDO68408.1 - 2.9e-15 55.1 0.1 3e-13 48.7 0.0 2.9 3 0 0 3 3 3 1 SHNi-TPR TPR_11 PF13414.1 CDO68408.1 - 6.8e-12 44.8 0.9 3e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 CDO68408.1 - 4.2e-09 36.2 9.9 5.6e-06 26.2 0.2 3.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDO68408.1 - 3.7e-06 26.3 0.1 0.34 10.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDO68408.1 - 0.0034 17.1 12.5 0.76 9.8 0.0 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 CDO68408.1 - 0.016 15.1 1.3 6.5 6.8 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CDO68408.1 - 0.071 12.9 5.6 5.8 6.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Gp_dh_C PF02800.15 CDO68408.1 - 0.12 11.8 0.2 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain TPR_7 PF13176.1 CDO68408.1 - 0.21 11.4 4.4 22 5.1 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 CDO68408.1 - 0.27 11.5 16.5 0.36 11.1 0.3 4.8 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CDO68408.1 - 0.7 10.6 20.3 1.7 9.3 0.9 4.6 3 1 3 6 6 5 0 Tetratricopeptide repeat Aldedh PF00171.17 CDO68409.1 - 4.2e-17 61.6 6.2 9.1e-13 47.3 3.7 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family FGGY_N PF00370.16 CDO68410.1 - 8.4e-62 208.6 0.1 4.3e-60 203.0 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CDO68410.1 - 5.4e-60 202.4 1.4 9e-60 201.6 1.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Glyco_hydro_47 PF01532.15 CDO68411.1 - 1.6e-119 399.5 0.0 1.9e-119 399.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ANTH PF07651.11 CDO68412.1 - 1.9e-55 187.5 0.1 2.9e-55 186.9 0.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 CDO68412.1 - 6.1e-05 22.8 0.0 0.00016 21.5 0.0 1.8 1 0 0 1 1 1 1 ENTH domain F-box PF00646.28 CDO68412.1 - 0.078 12.6 0.1 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 F-box domain DUF1720 PF08226.6 CDO68413.1 - 0.0012 18.8 25.3 0.0023 17.9 5.7 6.3 3 2 1 5 5 5 2 Domain of unknown function (DUF1720) E1-E2_ATPase PF00122.15 CDO68415.1 - 8.9e-51 172.1 0.9 2.7e-50 170.5 0.6 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CDO68415.1 - 2.8e-35 122.7 1.3 5.1e-35 121.8 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CDO68415.1 - 1.8e-24 85.6 0.0 3.2e-11 43.1 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 CDO68415.1 - 1.7e-10 41.3 0.0 5.7e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDO68415.1 - 0.00018 21.2 0.4 0.03 13.9 0.2 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DUF4218 PF13960.1 CDO68416.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Myb_DNA-bind_4 PF13837.1 CDO68417.1 - 5.9e-09 35.9 0.1 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO68417.1 - 1.6e-06 28.6 0.0 2.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO68417.1 - 4.4e-05 23.2 0.0 0.00017 21.3 0.0 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO68417.1 - 0.038 14.1 0.1 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF3773 PF12608.3 CDO68417.1 - 0.088 12.8 0.5 0.2 11.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3773) SNARE_assoc PF09335.6 CDO68418.1 - 1.4 9.1 8.1 1.3 9.2 4.9 1.6 1 1 1 2 2 2 0 SNARE associated Golgi protein RVT_2 PF07727.9 CDO68419.1 - 1.1e-84 283.2 0.0 1.7e-84 282.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_2 PF14227.1 CDO68419.1 - 3.8e-14 52.2 0.0 7.4e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO68419.1 - 4.3e-13 49.0 0.0 8.7e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.21 CDO68419.1 - 2.3e-07 30.9 0.2 4.7e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CDO68419.1 - 5.3e-06 25.9 0.0 1.8e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 CDO68419.1 - 0.00023 20.9 2.9 0.00058 19.6 2.0 1.7 1 0 0 1 1 1 1 Zinc knuckle SecY PF00344.15 CDO68422.1 - 6.3e-98 327.8 9.4 7.9e-98 327.5 6.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CDO68422.1 - 3.2e-19 68.1 0.2 1.2e-18 66.3 0.1 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p ThiF PF00899.16 CDO68423.1 - 0.022 14.5 0.1 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family EspF PF04806.7 CDO68424.1 - 0.68 10.1 2.8 8.1 6.7 0.4 2.5 2 0 0 2 2 2 0 EspF protein repeat p450 PF00067.17 CDO68425.1 - 3.3e-67 226.9 0.0 1.9e-66 224.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_60s PF00428.14 CDO68426.1 - 7.8e-28 96.7 9.8 9.7e-28 96.4 6.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Etmic-2 PF06670.6 CDO68426.1 - 0.0039 15.9 0.8 0.0042 15.8 0.5 1.0 1 0 0 1 1 1 1 Microneme protein Etmic-2 BTB PF00651.26 CDO68427.1 - 0.014 15.3 0.1 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain DUF3275 PF11679.3 CDO68427.1 - 8.2 6.0 6.4 1.5 8.4 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) EthD PF07110.6 CDO68428.1 - 2.4e-05 25.1 0.1 0.0055 17.6 0.0 2.8 2 1 0 2 2 2 2 EthD domain ABM PF03992.11 CDO68428.1 - 2.5 8.1 6.5 2.8 8.0 2.2 2.9 2 1 1 3 3 3 0 Antibiotic biosynthesis monooxygenase EthD PF07110.6 CDO68429.1 - 1.1e-09 39.1 0.0 0.00051 20.9 0.0 2.3 2 0 0 2 2 2 2 EthD domain ABM PF03992.11 CDO68429.1 - 0.011 15.7 0.1 0.029 14.3 0.1 1.7 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase ABM PF03992.11 CDO68430.1 - 0.18 11.8 1.6 0.26 11.3 0.1 2.1 1 1 0 2 2 2 0 Antibiotic biosynthesis monooxygenase BTB PF00651.26 CDO68431.1 - 0.022 14.7 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Rifin_STEVOR PF02009.11 CDO68432.1 - 0.94 9.0 4.1 0.4 10.2 0.4 1.9 1 1 0 2 2 2 0 Rifin/stevor family MLANA PF14991.1 CDO68433.1 - 0.00077 19.4 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 Protein melan-A TMEM190 PF15431.1 CDO68433.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 Sod_Fe_C PF02777.13 CDO68435.1 - 1.7e-37 127.5 0.4 2.8e-37 126.7 0.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CDO68435.1 - 6.4e-32 109.6 3.9 9.1e-32 109.1 1.7 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain QueF_N PF14819.1 CDO68435.1 - 0.1 12.7 0.2 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term ATP-synt_DE PF00401.15 CDO68435.1 - 0.49 10.3 4.9 0.45 10.4 1.3 2.1 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain RVT_2 PF07727.9 CDO68437.1 - 1.1e-87 293.0 0.0 1.8e-87 292.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO68437.1 - 9.4e-28 96.7 0.0 2.1e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CDO68437.1 - 5.1e-09 35.6 0.1 1.1e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CDO68437.1 - 1.5e-05 24.3 0.1 3.7e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Gemini_AC4_5_2 PF08464.5 CDO68439.1 - 0.096 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region UDP-g_GGTase PF06427.6 CDO68442.1 - 3e-53 180.2 0.0 5.5e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 CDO68442.1 - 1.9e-08 33.9 0.0 3.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Pkinase PF00069.20 CDO68443.1 - 1.2e-73 247.5 0.0 2.4e-73 246.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO68443.1 - 1.7e-44 151.8 0.0 2.9e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CDO68443.1 - 4.4e-32 109.8 0.7 2.2e-19 69.2 0.1 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CDO68443.1 - 1.1e-09 37.7 0.0 6.1e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CDO68443.1 - 0.003 16.6 0.1 0.025 13.6 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4520 PF15016.1 CDO68443.1 - 0.02 14.4 0.0 0.051 13.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Nsp1_C PF05064.8 CDO68444.1 - 0.0039 16.8 0.5 0.025 14.1 0.1 2.3 2 1 0 2 2 2 1 Nsp1-like C-terminal region V_ATPase_I PF01496.14 CDO68444.1 - 0.0079 14.1 1.1 0.01 13.7 0.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3713 PF12506.3 CDO68444.1 - 0.011 15.8 0.5 0.022 14.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) CortBP2 PF09727.4 CDO68444.1 - 0.036 13.5 6.3 0.035 13.5 3.6 1.5 1 1 0 1 1 1 0 Cortactin-binding protein-2 Dak1 PF02733.12 CDO68444.1 - 0.059 11.9 0.7 2.6 6.5 0.1 2.1 1 1 0 2 2 2 0 Dak1 domain NPV_P10 PF05531.7 CDO68444.1 - 0.08 13.1 1.8 1.9 8.8 0.3 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2934 PF11154.3 CDO68444.1 - 0.084 12.2 0.1 0.36 10.2 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) Baculo_PEP_C PF04513.7 CDO68444.1 - 0.63 9.8 3.7 4.5 7.0 2.5 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.1 CDO68444.1 - 1.7 8.5 9.1 9.6 6.1 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DivIC PF04977.10 CDO68444.1 - 4.6 6.7 6.6 0.91 9.0 1.3 2.4 3 0 0 3 3 3 0 Septum formation initiator Retrotrans_gag PF03732.12 CDO68445.1 - 6.4e-06 26.1 0.6 1.4e-05 25.0 0.4 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein CAP_N PF01213.14 CDO68446.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal tRNA_m1G_MT PF01746.16 CDO68447.1 - 4.7e-30 104.5 0.6 5.8e-25 87.9 0.2 2.4 1 1 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase CAF-1_p150 PF11600.3 CDO68447.1 - 0.0039 16.5 16.2 0.0039 16.5 11.2 2.3 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDO68447.1 - 0.0052 16.2 10.5 0.0052 16.2 7.3 2.6 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Methyltransf_23 PF13489.1 CDO68448.1 - 3.5e-08 33.3 0.0 2.5e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO68448.1 - 0.00031 21.1 0.0 0.00067 20.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO68448.1 - 0.00056 20.3 0.0 0.0014 19.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO68448.1 - 0.024 14.2 0.0 0.071 12.7 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain zf-C2H2_jaz PF12171.3 CDO68449.1 - 0.0014 18.7 4.1 0.016 15.3 2.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CDO68449.1 - 0.0034 17.6 13.8 2.6 8.5 0.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type Zip PF02535.17 CDO68450.1 - 0.32 9.9 0.0 0.57 9.1 0.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpb2_6 PF00562.23 CDO68451.1 - 3.5e-113 378.2 0.0 4.8e-113 377.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CDO68451.1 - 4.1e-33 114.0 0.0 7.1e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CDO68451.1 - 9.8e-27 92.5 0.0 2.8e-26 91.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 CDO68451.1 - 2.8e-22 79.0 0.0 6.7e-22 77.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 CDO68451.1 - 2.6e-21 75.3 0.0 6.2e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 CDO68451.1 - 3e-18 65.8 0.0 1.9e-14 53.6 0.1 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 CDO68451.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Prim_Zn_Ribbon PF08273.7 CDO68451.1 - 0.28 11.2 2.0 22 5.2 0.2 2.7 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Nucleoporin2 PF04096.9 CDO68452.1 - 9.4e-45 151.8 0.0 1.4e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CDO68452.1 - 4e-22 78.6 335.4 3.4e-08 33.6 37.1 10.1 4 4 5 9 9 9 7 Nucleoporin FG repeat region Yae1_N PF09811.4 CDO68453.1 - 0.014 14.9 5.6 0.03 13.8 3.9 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal IncA PF04156.9 CDO68453.1 - 1.5 8.4 12.3 2.2 7.8 8.5 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 CDO68453.1 - 2.1 6.0 3.3 2.8 5.6 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ABC_tran PF00005.22 CDO68455.1 - 5.5e-16 59.1 0.2 2.2e-15 57.1 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CDO68455.1 - 4.1e-12 46.6 0.6 5.3e-05 23.3 0.2 2.1 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 CDO68455.1 - 2.5e-06 26.8 0.0 0.043 12.8 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 CDO68455.1 - 4.8e-05 22.8 0.0 8.4e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CDO68455.1 - 0.00012 21.5 0.1 0.00032 20.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CDO68455.1 - 0.0012 18.0 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 CDO68455.1 - 0.0053 17.1 0.1 0.0086 16.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 CDO68455.1 - 0.0092 15.2 0.9 0.37 9.9 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 CDO68455.1 - 0.014 14.8 0.1 0.035 13.5 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 CDO68455.1 - 0.016 14.6 0.1 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 CDO68455.1 - 0.032 13.8 0.2 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 CDO68455.1 - 0.036 14.0 0.1 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CDO68455.1 - 0.061 12.7 0.1 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 CDO68455.1 - 0.062 14.1 1.1 0.15 12.8 0.8 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CDO68455.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 CDO68455.1 - 0.1 11.8 0.1 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family MutS_V PF00488.16 CDO68455.1 - 0.17 11.2 0.1 0.75 9.1 0.0 1.8 2 0 0 2 2 2 0 MutS domain V Miro PF08477.8 CDO68455.1 - 0.17 12.4 0.0 0.47 10.9 0.0 1.7 2 0 0 2 2 1 0 Miro-like protein Opy2 PF09463.5 CDO68456.1 - 0.00015 21.7 15.1 0.00025 21.0 10.5 1.4 1 0 0 1 1 1 1 Opy2 protein VSP PF03302.8 CDO68456.1 - 0.0044 15.7 4.9 0.0077 14.9 3.4 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.5 CDO68456.1 - 0.019 14.2 4.3 0.041 13.2 3.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain OppC_N PF12911.2 CDO68456.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C SKG6 PF08693.5 CDO68457.1 - 3.8e-05 22.8 1.6 8.4e-05 21.8 1.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 CDO68457.1 - 0.00099 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Opy2 PF09463.5 CDO68457.1 - 0.016 15.2 5.8 0.025 14.6 4.0 1.3 1 0 0 1 1 1 0 Opy2 protein DUF1777 PF08648.7 CDO68458.1 - 0.00092 18.9 35.7 0.00092 18.9 24.8 4.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1777) zf-CCHC PF00098.18 CDO68458.1 - 0.49 10.4 27.3 0.73 9.8 5.6 4.4 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.1 CDO68458.1 - 2.6 7.8 19.2 0.66 9.7 2.6 3.8 2 1 1 3 3 3 0 Zinc knuckle UQ_con PF00179.21 CDO68460.1 - 4.4e-10 39.1 0.0 9.2e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mito_carr PF00153.22 CDO68461.1 - 1.1e-48 162.9 0.2 1.5e-19 69.4 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 CDO68461.1 - 0.017 15.0 0.0 20 5.1 0.0 3.5 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase UBN2 PF14223.1 CDO68465.1 - 7.1e-12 45.1 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CDO68465.1 - 1.5e-11 43.8 0.0 2.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO68465.1 - 1.2e-05 24.8 0.0 0.00019 20.9 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Tbf5 PF06331.7 CDO68466.1 - 1.4e-17 63.1 0.3 2.2e-17 62.5 0.2 1.3 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Nucleoporin_FG PF13634.1 CDO68467.1 - 1.9e-19 69.9 118.8 3.6e-10 40.0 28.7 4.2 1 1 2 3 3 3 2 Nucleoporin FG repeat region PRP1_N PF06424.7 CDO68467.1 - 0.24 11.7 3.8 0.82 9.9 2.6 2.1 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Glyco_transf_17 PF04724.8 CDO68468.1 - 1.2e-101 340.3 0.0 1.4e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Actin PF00022.14 CDO68469.1 - 4.3e-30 104.4 0.0 5.4e-25 87.6 0.0 2.0 2 0 0 2 2 2 2 Actin Transposase_21 PF02992.9 CDO68471.1 - 1.3e-35 122.5 0.0 3.1e-35 121.3 0.0 1.6 1 1 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO68471.1 - 3.7e-07 29.6 0.1 9.6e-07 28.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) PX PF00787.19 CDO68472.1 - 0.003 17.3 0.0 0.015 15.1 0.0 2.1 1 1 0 1 1 1 1 PX domain Aldo_ket_red PF00248.16 CDO68473.1 - 5.6e-67 225.5 0.0 7e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GATA PF00320.22 CDO68474.1 - 4.9e-15 54.5 3.6 1.4e-14 53.1 2.5 1.8 1 0 0 1 1 1 1 GATA zinc finger TauD PF02668.11 CDO68475.1 - 6.8e-51 173.4 0.4 8.8e-51 173.0 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UCH PF00443.24 CDO68477.1 - 1.5e-47 161.9 0.0 1.9e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDO68477.1 - 1.2e-24 87.2 0.0 1.7e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ODV-E18 PF10717.4 CDO68477.1 - 0.35 10.3 2.7 0.76 9.2 1.9 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF3292 PF11696.3 CDO68478.1 - 1.5e-179 597.9 0.0 2e-151 505.0 0.0 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF3292) CPSase_L_D2 PF02786.12 CDO68478.1 - 9.3e-69 230.9 0.0 5.9e-68 228.3 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 CDO68478.1 - 3.1e-33 113.9 0.1 4e-32 110.3 0.0 2.7 2 1 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 CDO68478.1 - 1.7e-15 57.0 0.0 8.9e-15 54.7 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 CDO68478.1 - 1.6e-13 50.7 0.1 8.6e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CDO68478.1 - 3.9e-09 36.1 0.0 8.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 CDO68478.1 - 1.2e-08 34.0 0.0 5.1e-08 32.0 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CDO68478.1 - 4.7e-08 32.5 0.0 2.3e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain PRT_C PF08372.5 CDO68478.1 - 0.00072 19.0 0.1 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Toxin_59 PF15537.1 CDO68478.1 - 0.074 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 59 ATP-grasp_3 PF02655.9 CDO68478.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DUF639 PF04842.7 CDO68478.1 - 0.53 8.3 0.1 0.81 7.7 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) F-box-like PF12937.2 CDO68480.1 - 8.5e-10 38.2 0.2 3.6e-09 36.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDO68480.1 - 0.00069 19.2 3.4 0.00091 18.8 0.0 2.8 3 0 0 3 3 3 1 F-box domain DUF3292 PF11696.3 CDO68481.1 - 1.4e-121 406.4 1.1 1.6e-72 244.4 0.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.5 CDO68481.1 - 0.00013 21.5 0.1 0.00024 20.6 0.1 1.4 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Adeno_GP19K PF04881.8 CDO68481.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus GP19K UCH PF00443.24 CDO68482.1 - 4.6e-44 150.5 0.0 1.9e-43 148.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 CDO68482.1 - 2.7e-28 97.1 0.2 2.7e-19 68.3 0.0 2.6 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.1 CDO68482.1 - 1.6e-14 54.0 1.9 1.5e-08 34.4 0.3 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase NnrU PF07298.6 CDO68482.1 - 0.071 12.4 1.0 0.17 11.2 0.7 1.6 1 0 0 1 1 1 0 NnrU protein ABC_ATPase PF09818.4 CDO68483.1 - 4.4e-133 444.1 0.0 2.2e-128 428.6 0.0 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 CDO68483.1 - 0.00026 20.4 0.1 0.0008 18.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CDO68483.1 - 0.035 13.6 0.1 0.077 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Terminase_4 PF05119.7 CDO68483.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage terminase, small subunit HET PF06985.6 CDO68484.1 - 3.2e-24 85.6 8.1 3.2e-24 85.6 5.6 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 CDO68484.1 - 6.4e-08 32.1 0.8 0.002 17.9 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat HET PF06985.6 CDO68485.1 - 2.6e-18 66.5 7.1 2.3e-16 60.2 1.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 CDO68485.1 - 1.6e-06 27.7 0.1 0.19 11.6 0.0 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat NAD_binding_1 PF00175.16 CDO68486.1 - 1.3e-26 93.2 0.0 2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CDO68486.1 - 7e-18 64.5 0.0 1.9e-17 63.2 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CDO68486.1 - 7.9e-06 25.8 0.0 7.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CDO68486.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF3457 PF11939.3 CDO68486.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3457) Pkinase PF00069.20 CDO68487.1 - 1.9e-63 214.0 0.0 1.6e-62 211.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO68487.1 - 1.2e-24 86.7 0.0 1.5e-23 83.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PHP PF02811.14 CDO68488.1 - 1.4e-08 34.6 0.0 5.2e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 PHP domain Sel1 PF08238.7 CDO68490.1 - 3.4e-47 157.8 32.7 5.6e-10 39.5 0.1 8.3 8 0 0 8 8 8 7 Sel1 repeat Hormone_2 PF00123.15 CDO68492.1 - 0.14 12.0 2.1 1.9 8.3 0.0 2.9 3 0 0 3 3 3 0 Peptide hormone F-box PF00646.28 CDO68494.1 - 0.026 14.1 0.3 0.17 11.5 0.0 2.4 3 0 0 3 3 3 0 F-box domain FA_desaturase PF00487.19 CDO68495.1 - 2.7 7.3 7.4 0.98 8.8 1.9 2.0 2 0 0 2 2 2 0 Fatty acid desaturase ubiquitin PF00240.18 CDO68496.1 - 2.9e-21 74.6 0.2 4.9e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CDO68496.1 - 2.3e-12 46.4 0.1 3.6e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 CDO68496.1 - 1.6e-10 40.4 0.1 4.1e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.4 CDO68496.1 - 2e-06 27.8 0.0 3.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CDO68496.1 - 0.0013 18.6 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CDO68496.1 - 0.009 16.2 0.2 0.026 14.7 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Phage_tail_X PF05489.7 CDO68496.1 - 0.041 13.3 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X XPC-binding PF09280.6 CDO68496.1 - 0.094 12.1 7.7 0.22 11.0 3.8 2.7 1 1 1 2 2 2 0 XPC-binding domain CUE PF02845.11 CDO68496.1 - 3.7 7.1 5.9 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 CUE domain Dus PF01207.12 CDO68497.1 - 6.8e-71 238.6 0.0 8.9e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.12 CDO68497.1 - 0.00042 19.9 0.1 0.053 13.0 0.0 2.2 1 1 1 2 2 2 2 SOR/SNZ family ThiG PF05690.9 CDO68497.1 - 0.0017 17.4 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 CDO68497.1 - 0.0096 15.2 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.16 CDO68497.1 - 0.012 14.6 0.0 0.029 13.3 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NMO PF03060.10 CDO68497.1 - 0.015 14.4 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase IMPDH PF00478.20 CDO68497.1 - 0.018 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF849 PF05853.7 CDO68497.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) HATPase_c PF02518.21 CDO68498.1 - 2.5e-27 94.7 0.0 6.4e-27 93.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CDO68498.1 - 6.5e-25 87.3 0.0 1.7e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain MHYT PF03707.11 CDO68498.1 - 2.3e-18 66.0 23.4 9.7e-12 44.8 1.3 3.8 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat HisKA PF00512.20 CDO68498.1 - 2.5e-14 53.0 0.1 1.3e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 CDO68498.1 - 0.00077 19.1 0.0 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 GHKL domain OCD_Mu_crystall PF02423.10 CDO68498.1 - 0.022 13.5 0.1 0.04 12.6 0.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Tetraspannin PF00335.15 CDO68499.1 - 1.9e-12 46.9 9.1 2.6e-12 46.5 6.3 1.2 1 0 0 1 1 1 1 Tetraspanin family FTR1 PF03239.9 CDO68499.1 - 0.0095 14.9 0.2 0.018 14.0 0.1 1.4 1 0 0 1 1 1 1 Iron permease FTR1 family Metalloenzyme PF01676.13 CDO68500.1 - 4.7e-75 252.2 1.6 5.4e-75 252.0 1.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 CDO68500.1 - 5.8e-75 251.4 0.1 8.8e-75 250.8 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 CDO68500.1 - 4.1e-05 23.0 0.1 6.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CDO68500.1 - 9.8e-05 21.6 0.0 0.00082 18.6 0.0 2.1 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.7 CDO68500.1 - 0.00083 19.0 0.0 0.0026 17.4 0.0 1.8 2 0 0 2 2 2 1 PglZ domain DLH PF01738.13 CDO68501.1 - 8.6e-11 41.5 0.0 7.5e-09 35.1 0.0 2.8 1 1 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.13 CDO68502.1 - 1.4e-19 70.3 0.0 1.6e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CDO68502.1 - 1.1e-06 28.5 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hus1 PF04005.7 CDO68503.1 - 3.9e-51 173.7 0.0 3.4e-36 124.6 0.0 2.0 1 1 1 2 2 2 2 Hus1-like protein NADHdh_A3 PF14987.1 CDO68505.1 - 0.019 14.8 0.2 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Cation_ATPase_C PF00689.16 CDO68505.1 - 0.098 12.1 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Kdo PF06293.9 CDO68506.1 - 7e-09 35.0 0.0 5.3e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 CDO68506.1 - 3.3e-05 23.1 0.0 4.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 CDO68506.1 - 4.6e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CDO68506.1 - 7.5e-05 21.9 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 CDO68506.1 - 0.01 15.2 0.0 0.078 12.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.12 CDO68506.1 - 0.23 10.4 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase NIF PF03031.13 CDO68507.1 - 6.7e-15 55.1 0.0 2.8e-14 53.1 0.0 1.9 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase EamA PF00892.15 CDO68508.1 - 9e-16 58.0 29.9 9.3e-14 51.5 7.3 3.4 2 1 1 3 3 3 3 EamA-like transporter family EmrE PF13536.1 CDO68508.1 - 6.2e-08 32.8 28.9 9e-08 32.3 2.8 3.9 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 CDO68508.1 - 0.00023 20.8 6.4 0.00023 20.8 4.5 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family E1-N PF14463.1 CDO68508.1 - 0.022 14.3 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 E1 N-terminal domain Serinc PF03348.10 CDO68508.1 - 0.027 13.1 1.2 0.67 8.5 0.7 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) Ion_trans PF00520.26 CDO68509.1 - 6.8e-84 280.0 79.9 2.1e-30 105.4 8.6 5.3 5 0 0 5 5 5 4 Ion transport protein Tubulin PF00091.20 CDO68510.1 - 6.7e-71 238.5 0.0 1.4e-70 237.4 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CDO68510.1 - 1.1e-48 164.4 0.2 1.7e-48 163.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CDO68510.1 - 8e-07 29.1 0.8 1.8e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Hydantoinase_A PF01968.13 CDO68511.1 - 6e-90 301.2 0.0 8.7e-90 300.7 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CDO68511.1 - 5e-56 188.9 0.2 3e-52 176.6 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 CDO68511.1 - 0.032 12.5 0.1 0.053 11.8 0.0 1.3 1 0 0 1 1 1 0 MutL protein ENTH PF01417.15 CDO68512.1 - 3e-51 172.4 0.1 3e-51 172.4 0.1 1.7 2 0 0 2 2 2 1 ENTH domain NlpE PF04170.7 CDO68512.1 - 0.087 13.2 6.8 0.47 10.8 4.7 2.3 1 0 0 1 1 1 0 NlpE N-terminal domain PCI PF01399.22 CDO68513.1 - 1.8e-09 37.8 3.4 1.3e-07 31.8 0.0 3.4 3 0 0 3 3 3 2 PCI domain SEP PF08059.8 CDO68513.1 - 0.22 11.8 1.2 52 4.2 0.0 3.4 3 0 0 3 3 3 0 SEP domain Cys_Met_Meta_PP PF01053.15 CDO68515.1 - 2e-121 404.9 0.0 1.6e-66 224.2 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CDO68515.1 - 1.6e-08 34.0 0.9 1e-07 31.3 0.2 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CDO68515.1 - 8.8e-07 28.1 0.0 1.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CDO68515.1 - 0.015 14.0 0.6 0.12 11.0 0.0 2.4 2 1 0 2 2 2 0 Aminotransferase class-V Beta_elim_lyase PF01212.16 CDO68515.1 - 0.03 13.4 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase zf-C2H2_4 PF13894.1 CDO68516.1 - 0.00032 20.8 12.0 0.023 14.9 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CDO68516.1 - 0.1 12.7 1.2 11 6.2 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-HYPF PF07503.7 CDO68516.1 - 0.41 10.0 4.0 0.34 10.3 0.6 2.3 2 0 0 2 2 2 0 HypF finger zf-C2H2 PF00096.21 CDO68516.1 - 1.2 9.6 17.0 0.23 11.8 1.7 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2 PF00096.21 CDO68517.1 - 5.8e-09 35.7 12.4 3.5e-06 27.0 0.2 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO68517.1 - 2.2e-08 33.9 0.4 2.2e-08 33.9 0.3 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 CDO68517.1 - 1.6e-05 24.6 1.0 0.45 10.4 0.0 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CDO68517.1 - 3.8e-05 23.6 11.0 0.0011 19.1 0.2 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 CDO68517.1 - 0.1 12.8 2.8 3 8.1 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CDO68517.1 - 0.17 12.0 1.1 2.6 8.3 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CDO68517.1 - 0.83 9.8 6.3 1.9 8.6 0.3 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3294 PF07957.6 CDO68519.1 - 0.00078 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Peptidase_M36 PF02128.10 CDO68520.1 - 7.8e-132 439.6 9.3 4.1e-131 437.2 6.4 2.1 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 CDO68520.1 - 1e-10 40.8 1.9 2.1e-10 39.9 1.3 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 CDO68520.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Phage_G PF02306.10 CDO68520.1 - 0.1 12.2 0.0 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 Major spike protein (G protein) DUF3782 PF12644.2 CDO68520.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Cys_Met_Meta_PP PF01053.15 CDO68521.1 - 1.1e-137 458.4 0.0 1.3e-137 458.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CDO68521.1 - 1.8e-11 43.7 0.1 3.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CDO68521.1 - 1.7e-09 37.1 0.0 2.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CDO68521.1 - 2e-09 36.6 1.6 3.9e-08 32.4 0.1 2.8 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CDO68521.1 - 0.00044 19.4 0.0 0.00077 18.6 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 CDO68521.1 - 0.0067 14.7 0.3 0.013 13.7 0.2 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 CDO68521.1 - 0.029 13.0 0.0 0.043 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.15 CDO68522.1 - 5.1e-143 476.0 0.0 5.8e-143 475.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CDO68522.1 - 4.4e-13 49.0 0.1 3.9e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CDO68522.1 - 8.6e-10 38.0 0.0 1.7e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CDO68522.1 - 2.3e-09 36.4 0.9 1.8e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CDO68522.1 - 2.4e-06 26.9 0.0 5.9e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 CDO68522.1 - 0.00023 19.6 0.0 0.00032 19.1 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 CDO68522.1 - 0.0057 15.3 0.0 0.0085 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 CDO68522.1 - 0.048 12.1 0.0 0.075 11.4 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) dsrm PF00035.20 CDO68523.1 - 1.7 9.2 5.5 19 5.9 0.0 3.8 4 0 0 4 4 4 0 Double-stranded RNA binding motif PhyH PF05721.8 CDO68524.1 - 1.6e-13 51.2 0.1 2.1e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ras PF00071.17 CDO68525.1 - 1.8e-50 170.4 0.0 2.1e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO68525.1 - 3e-16 59.9 0.0 4.5e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO68525.1 - 1.9e-12 46.7 0.0 2.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO68525.1 - 2.2e-07 30.2 0.0 2.6e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CDO68525.1 - 1e-05 25.4 0.0 3.3e-05 23.8 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CDO68525.1 - 0.0045 16.4 0.0 0.015 14.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.13 CDO68525.1 - 0.022 13.7 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Septin SRPRB PF09439.5 CDO68525.1 - 0.024 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CDO68525.1 - 0.07 13.1 0.1 0.34 10.8 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CDO68525.1 - 0.075 12.2 0.1 0.19 10.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 CDO68525.1 - 0.08 11.6 0.6 1.8 7.1 0.1 2.1 1 1 0 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 CDO68525.1 - 0.12 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Na_Ca_ex PF01699.19 CDO68526.1 - 2.2e-10 40.2 16.7 0.00023 20.8 0.5 3.9 3 2 0 3 3 3 3 Sodium/calcium exchanger protein Na_Ca_ex PF01699.19 CDO68527.1 - 5.9e-13 48.6 18.4 5.6e-07 29.2 4.3 2.6 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Methyltransf_23 PF13489.1 CDO68528.1 - 3.1e-11 43.2 0.0 4.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO68528.1 - 4.6e-08 33.4 0.0 1.1e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO68528.1 - 1.2e-05 24.9 0.0 2.2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO68528.1 - 1.8e-05 25.2 0.0 3.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO68528.1 - 7.2e-05 23.2 0.0 0.00029 21.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Acyltransferase PF01553.16 CDO68529.1 - 1.2e-11 44.1 0.0 1.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PAP2 PF01569.16 CDO68530.1 - 3.5e-10 39.6 9.7 3.5e-10 39.6 6.7 2.6 2 1 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 CDO68530.1 - 3e-08 33.4 9.0 7.9e-08 32.0 6.3 1.7 1 0 0 1 1 1 1 PAP2 superfamily DUF4243 PF14027.1 CDO68531.1 - 2e-87 293.7 0.0 2.4e-87 293.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF4243 PF14027.1 CDO68532.1 - 7.4e-90 301.7 0.0 8.9e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Mannosyl_trans2 PF04188.8 CDO68533.1 - 4.3e-54 184.0 19.4 2e-53 181.8 13.5 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) FA_hydroxylase PF04116.8 CDO68534.1 - 3.3e-11 43.5 21.7 3.3e-11 43.5 15.0 2.4 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily GST_N_3 PF13417.1 CDO68535.1 - 1.4e-12 47.6 0.1 3e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO68535.1 - 2.3e-09 37.1 0.1 4.3e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO68535.1 - 0.0008 19.5 0.0 0.0079 16.3 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO68535.1 - 0.0026 17.6 1.9 0.0047 16.7 0.4 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO68535.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LRR_4 PF12799.2 CDO68536.1 - 0.21 11.2 1.7 69 3.2 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) CMAS PF02353.15 CDO68537.1 - 1.9e-45 155.0 0.0 4.7e-24 84.9 0.0 2.2 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CDO68537.1 - 3.5e-05 23.5 0.0 7.7e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO68537.1 - 0.00061 20.2 0.0 0.0016 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain SAC3 PF12209.3 CDO68537.1 - 0.097 12.8 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain Methyltransf_31 PF13847.1 CDO68537.1 - 0.16 11.5 0.0 0.52 9.8 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain Xan_ur_permease PF00860.15 CDO68538.1 - 1.8e-30 105.7 29.5 5.8e-18 64.5 9.1 2.4 3 0 0 3 3 3 2 Permease family RNA_pol_Rpc34 PF05158.7 CDO68539.1 - 1.5e-38 132.7 0.1 2e-38 132.4 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RAI16-like PF10257.4 CDO68539.1 - 0.049 12.5 0.0 0.095 11.6 0.0 1.4 1 1 0 1 1 1 0 Retinoic acid induced 16-like protein CPSase_L_D2 PF02786.12 CDO68540.1 - 9.2e-116 384.5 0.1 1.2e-84 282.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CDO68540.1 - 1.6e-46 157.0 0.0 4e-46 155.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 CDO68540.1 - 6.8e-43 145.3 0.1 1.4e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.16 CDO68540.1 - 1.8e-42 144.3 0.0 4.3e-42 143.1 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.23 CDO68540.1 - 4.2e-41 140.5 0.0 1.2e-40 138.9 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 CDO68540.1 - 5.4e-41 139.1 0.0 2e-19 69.7 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 CDO68540.1 - 3e-37 128.1 0.1 4.9e-22 78.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 CDO68540.1 - 2.7e-36 124.8 0.0 7.5e-36 123.3 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 CDO68540.1 - 3.8e-21 75.1 0.0 2.7e-09 36.2 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 CDO68540.1 - 8.1e-19 67.3 0.0 4.3e-18 65.0 0.0 2.4 2 0 0 2 2 1 1 MGS-like domain ATP-grasp PF02222.17 CDO68540.1 - 1.9e-17 63.1 0.0 1e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CDO68540.1 - 3.8e-17 62.3 0.2 2.4e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CDO68540.1 - 1e-06 28.7 0.1 0.036 13.9 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 CDO68540.1 - 2.3e-05 23.9 0.0 0.00092 18.7 0.0 2.7 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 CDO68540.1 - 3.3e-05 23.4 0.0 0.005 16.3 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.19 CDO68540.1 - 0.0085 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family GARS_A PF01071.14 CDO68540.1 - 0.081 12.4 0.1 0.8 9.2 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 CDO68540.1 - 0.17 11.1 0.0 1.8 7.7 0.1 2.2 2 0 0 2 2 2 0 ATP-grasp domain MFS_1 PF07690.11 CDO68542.1 - 4.9e-40 137.3 56.2 6e-37 127.1 40.4 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily WBP-1 PF11669.3 CDO68542.1 - 0.074 13.1 0.1 2.8 8.0 0.1 2.5 2 0 0 2 2 2 0 WW domain-binding protein 1 BatD PF13584.1 CDO68542.1 - 0.27 9.7 0.1 9.3 4.7 0.1 2.1 2 0 0 2 2 2 0 Oxygen tolerance DUF2140 PF09911.4 CDO68542.1 - 0.43 9.7 3.9 11 5.1 0.6 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) zf-MYND PF01753.13 CDO68543.1 - 7.8e-10 38.4 12.4 1.3e-09 37.8 8.6 1.3 1 0 0 1 1 1 1 MYND finger zinc_ribbon_2 PF13240.1 CDO68543.1 - 0.046 13.2 4.3 0.15 11.5 3.0 1.9 1 0 0 1 1 1 0 zinc-ribbon domain Ecl1 PF12855.2 CDO68543.1 - 0.27 10.5 2.3 0.54 9.6 1.6 1.5 1 0 0 1 1 1 0 Life-span regulatory factor Jiv90 PF14901.1 CDO68543.1 - 0.9 9.5 4.8 0.092 12.7 0.4 1.5 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone zf-ribbon_3 PF13248.1 CDO68543.1 - 3 7.1 7.6 0.61 9.3 2.7 1.8 2 0 0 2 2 2 0 zinc-ribbon domain DnaJ-X PF14308.1 CDO68544.1 - 3.5e-53 179.9 3.1 3.5e-53 179.9 2.2 1.7 2 0 0 2 2 2 1 X-domain of DnaJ-containing tRNA-synt_1b PF00579.20 CDO68544.1 - 5.5e-42 143.8 0.0 1.4e-35 122.8 0.0 3.5 3 1 0 3 3 3 2 tRNA synthetases class I (W and Y) DnaJ PF00226.26 CDO68544.1 - 1.4e-13 50.3 0.5 1.4e-13 50.3 0.3 3.0 2 1 1 3 3 3 1 DnaJ domain FtsJ PF01728.14 CDO68545.1 - 1.1e-29 103.6 0.0 2.5e-29 102.5 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Histone PF00125.19 CDO68546.1 - 1.5e-13 50.6 0.1 2e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CDO68546.1 - 4.7e-05 23.4 0.0 7e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CDO68546.1 - 0.00011 22.1 0.2 0.00021 21.1 0.1 1.6 1 1 1 2 2 2 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CDO68546.1 - 0.0012 18.9 0.1 0.0024 17.9 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CDO68546.1 - 0.041 13.6 0.5 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated CENP-T PF15511.1 CDO68546.1 - 0.086 12.0 0.0 0.086 12.0 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CDO68546.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIIIC_sub6 PF10419.4 CDO68547.1 - 3.7e-06 26.2 0.1 8.3e-06 25.1 0.1 1.6 1 0 0 1 1 1 1 TFIIIC subunit MFS_1 PF07690.11 CDO68548.1 - 1.2e-31 109.7 45.2 1.2e-31 109.7 31.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily S10_plectin PF03501.10 CDO68548.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain Hydrophobin PF01185.13 CDO68549.1 - 0.44 11.0 5.0 1.1 9.7 3.5 1.6 1 1 0 1 1 1 0 Fungal hydrophobin PT PF04886.7 CDO68549.1 - 2.2 7.6 13.0 2.2 7.6 1.7 3.3 2 1 1 3 3 3 0 PT repeat TLV_coat PF00429.14 CDO68550.1 - 0.18 10.2 1.1 0.21 9.9 0.7 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) PT PF04886.7 CDO68550.1 - 0.66 9.3 19.2 0.057 12.7 2.2 4.2 2 1 2 4 4 4 0 PT repeat p450 PF00067.17 CDO68551.1 - 1.1e-52 179.1 0.0 1.9e-45 155.2 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 ArsB PF02040.10 CDO68551.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Arsenical pump membrane protein adh_short PF00106.20 CDO68552.1 - 1.6e-12 47.6 0.3 3.6e-12 46.5 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO68552.1 - 3.5e-05 23.7 0.0 4.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO68552.1 - 0.00055 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO68552.1 - 0.00079 18.9 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Hydrophobin PF01185.13 CDO68554.1 - 2.4e-21 75.9 8.5 3.7e-21 75.3 5.9 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 CDO68555.1 - 2.7e-07 30.9 0.6 4.5e-07 30.2 0.4 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 CDO68556.1 - 1.3e-14 54.3 7.3 1.7e-14 53.9 5.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Septin PF00735.13 CDO68557.1 - 7.1e-114 379.5 0.3 9.9e-114 379.1 0.2 1.2 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 CDO68557.1 - 4.3e-07 29.2 0.0 1.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CDO68557.1 - 6.8e-07 29.2 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CDO68557.1 - 1.7e-06 27.6 0.1 0.0001 21.8 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CDO68557.1 - 0.00023 20.3 0.0 0.00044 19.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 CDO68557.1 - 0.00075 19.9 0.2 0.0028 18.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 CDO68557.1 - 0.0015 18.8 0.2 0.011 16.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 CDO68557.1 - 0.0016 18.5 0.9 0.013 15.6 0.0 2.6 2 2 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CDO68557.1 - 0.0018 17.7 1.2 0.063 12.7 0.2 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 CDO68557.1 - 0.0038 17.0 6.9 0.37 10.6 0.0 2.9 2 1 1 3 3 3 2 Dynamin family Ras PF00071.17 CDO68557.1 - 0.0082 15.5 0.1 0.024 14.0 0.1 1.8 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.1 CDO68557.1 - 0.0095 15.9 1.3 0.05 13.5 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 CDO68557.1 - 0.015 14.9 1.9 0.02 14.5 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 CDO68557.1 - 0.019 14.5 0.0 0.048 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CDO68557.1 - 0.019 14.4 0.0 0.032 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain MobB PF03205.9 CDO68557.1 - 0.033 13.8 0.2 0.075 12.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CDO68557.1 - 0.042 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 CDO68557.1 - 0.046 13.6 0.4 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CDO68557.1 - 0.1 11.4 0.4 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Pox_A32 PF04665.7 CDO68557.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.1 CDO68557.1 - 0.12 12.2 0.6 0.52 10.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CDO68557.1 - 0.12 11.7 0.6 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 CDO68557.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 CDO68557.1 - 0.17 11.3 0.5 15 5.0 0.0 2.5 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Frankia_peptide PF14407.1 CDO68559.1 - 0.014 15.1 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. HA2 PF04408.18 CDO68562.1 - 3.5e-28 97.6 0.1 7.5e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CDO68562.1 - 8.2e-26 90.0 0.0 2.9e-25 88.3 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CDO68562.1 - 2.6e-06 27.0 0.2 1.2e-05 24.8 0.2 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 CDO68562.1 - 0.00037 19.9 0.2 0.0029 17.1 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 CDO68562.1 - 0.0011 19.1 1.7 0.77 9.9 0.0 3.0 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 CDO68562.1 - 0.0048 15.8 0.0 0.0095 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 CDO68562.1 - 0.052 13.3 0.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CDO68562.1 - 0.13 11.4 0.1 0.56 9.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 CDO68562.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Proteasome PF00227.21 CDO68563.1 - 2.3e-19 69.4 0.1 2.8e-18 65.9 0.1 2.0 1 1 0 1 1 1 1 Proteasome subunit RVT_2 PF07727.9 CDO68565.1 - 4.4e-88 294.4 0.0 6.9e-88 293.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 CDO68566.1 - 0.031 14.0 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Phage_integrase PF00589.17 CDO68567.1 - 0.061 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Phage integrase family DDE_3 PF13358.1 CDO68568.1 - 2.6e-24 85.6 0.0 4.9e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 CDO68568.1 - 8.6e-07 29.6 0.4 2.6e-06 28.1 0.2 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CDO68568.1 - 1.9e-06 28.0 1.5 3.4e-06 27.1 0.5 1.8 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.21 CDO68568.1 - 1.5e-05 25.1 0.0 5.6e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 CDO68568.1 - 7.8e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.1 CDO68568.1 - 0.079 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix BLVR PF06375.6 CDO68569.1 - 0.013 15.3 5.9 0.029 14.2 4.1 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) PAT1 PF09770.4 CDO68569.1 - 0.34 9.1 0.0 0.34 9.1 0.0 3.1 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 zf-CCHC_6 PF15288.1 CDO68570.1 - 0.00069 19.2 0.9 0.0016 18.0 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle Ycf1 PF05758.7 CDO68577.1 - 0.3 8.7 5.6 0.35 8.5 3.9 1.1 1 0 0 1 1 1 0 Ycf1 YqfQ PF14181.1 CDO68577.1 - 0.77 9.7 6.8 1.5 8.8 4.7 1.4 1 0 0 1 1 1 0 YqfQ-like protein SPX PF03105.14 CDO68577.1 - 0.97 9.1 6.6 1.2 8.9 4.3 1.3 1 1 0 1 1 1 0 SPX domain RP-C_C PF11800.3 CDO68577.1 - 2 8.0 12.0 5.7 6.5 5.1 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region CDC45 PF02724.9 CDO68577.1 - 2.1 6.2 9.5 2.5 6.0 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein GRP PF07172.6 CDO68577.1 - 3.2 8.2 19.2 0.47 10.9 2.0 2.7 2 1 0 2 2 2 0 Glycine rich protein family rve PF00665.21 CDO68578.1 - 7.4e-23 80.9 0.0 1.4e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO68578.1 - 3.3e-06 26.6 0.2 6.8e-06 25.6 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CDO68578.1 - 0.00046 19.5 0.0 0.00085 18.6 0.0 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Imm47 PF15586.1 CDO68578.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 47 DUF2550 PF10739.4 CDO68579.1 - 0.03 14.2 0.7 0.06 13.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) RVT_1 PF00078.22 CDO68580.1 - 4.8e-44 150.2 0.1 3.2e-24 85.5 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO68580.1 - 2.2e-05 23.5 0.1 0.17 10.8 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF503 PF04456.7 CDO68580.1 - 0.0025 17.3 2.1 1.5 8.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF503) CobD_Cbib PF03186.8 CDO68580.1 - 0.0075 15.3 0.0 0.95 8.4 0.0 2.2 2 0 0 2 2 2 2 CobD/Cbib protein DUF4325 PF14213.1 CDO68580.1 - 0.1 12.2 0.2 9 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4325) Retrotrans_gag PF03732.12 CDO68581.1 - 2.1e-10 40.5 0.0 4.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO68581.1 - 0.013 15.4 0.3 0.02 14.8 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 CDO68582.1 - 1.1e-12 47.8 0.1 3.4e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2 PF14223.1 CDO68582.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Smg4_UPF3 PF03467.10 CDO68583.1 - 4.4e-34 117.9 0.6 9.9e-34 116.8 0.4 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family DUF4121 PF13497.1 CDO68583.1 - 0.1 11.6 0.2 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) COesterase PF00135.23 CDO68585.1 - 3e-101 339.7 0.1 7.7e-101 338.4 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CDO68585.1 - 2.8e-13 49.9 0.4 7.4e-13 48.5 0.3 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDO68585.1 - 0.0014 17.8 0.1 0.0027 16.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 CDO68585.1 - 0.0042 16.5 0.8 0.011 15.1 0.5 1.5 1 1 0 1 1 1 1 Putative esterase DUF2424 PF10340.4 CDO68585.1 - 0.078 11.6 0.1 0.9 8.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) DUF2600 PF10776.4 CDO68586.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) tRNA-synt_2b PF00587.20 CDO68587.1 - 4.8e-44 149.9 0.2 8.2e-44 149.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CDO68587.1 - 7.7e-18 64.2 0.2 2e-17 62.8 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.16 CDO68587.1 - 1.6e-16 59.8 0.0 3.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 CDO68587.1 - 7.5e-12 44.9 0.0 1.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MBOAT_2 PF13813.1 CDO68588.1 - 1.5e-15 56.9 1.6 1.5e-15 56.9 1.1 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.1 CDO68589.1 - 9e-20 70.5 7.8 2.2e-19 69.2 5.4 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.1 CDO68590.1 - 1e-17 63.9 8.3 1.4e-17 63.4 4.2 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF4577 PF15145.1 CDO68590.1 - 0.15 11.9 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Pyridoxal_deC PF00282.14 CDO68591.1 - 2.3e-95 319.2 0.0 3.9e-94 315.1 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CDO68591.1 - 0.0057 15.4 0.0 0.012 14.4 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CDO68591.1 - 0.0082 15.1 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 CDO68591.1 - 0.022 13.3 0.0 0.042 12.3 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain MFS_1 PF07690.11 CDO68592.1 - 1.6e-24 86.3 36.2 1.6e-24 86.3 25.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Pyr_redox_2 PF07992.9 CDO68593.1 - 4.4e-20 72.4 0.0 1.6e-19 70.5 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO68593.1 - 1.4e-07 31.8 0.2 0.0079 16.5 0.2 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDO68593.1 - 0.0046 17.0 0.5 0.85 9.6 0.1 3.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase WH1 PF00568.18 CDO68594.1 - 3.6e-11 42.7 0.0 6.7e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 WH1 domain Nol1_Nop2_Fmu PF01189.12 CDO68595.1 - 6.9e-26 91.2 0.0 4.3e-21 75.5 0.0 3.8 2 1 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CDO68595.1 - 0.023 14.6 0.0 0.049 13.6 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 CDO68595.1 - 0.1 12.5 0.0 0.4 10.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain SNF5 PF04855.7 CDO68596.1 - 2.1e-72 243.5 1.0 2.1e-72 243.5 0.7 2.3 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Elf1 PF05129.8 CDO68596.1 - 0.017 14.7 0.3 0.11 12.1 0.2 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like GATA PF00320.22 CDO68596.1 - 0.31 10.4 6.5 0.62 9.4 4.5 1.5 1 0 0 1 1 1 0 GATA zinc finger NAD_binding_6 PF08030.7 CDO68597.1 - 6.5e-38 130.0 0.0 1.2e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CDO68597.1 - 1.6e-22 79.3 0.0 3.9e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 CDO68597.1 - 1.3e-16 60.8 8.5 1.3e-16 60.8 5.9 2.4 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 CDO68597.1 - 3.3e-06 27.1 0.0 7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Pam17 PF08566.5 CDO68597.1 - 0.092 12.4 0.2 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Glyco_hydro_28 PF00295.12 CDO68598.1 - 1.1e-32 113.3 0.0 1.5e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF953 PF06110.6 CDO68598.1 - 0.093 12.1 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Beta_helix PF13229.1 CDO68598.1 - 0.13 12.0 1.3 0.72 9.5 0.9 2.3 1 1 0 1 1 1 0 Right handed beta helix region HTH_32 PF13565.1 CDO68599.1 - 0.012 16.3 0.0 0.022 15.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_23 PF13384.1 CDO68599.1 - 0.027 14.1 0.1 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.1 CDO68599.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn helix ABC_tran PF00005.22 CDO68600.1 - 5.1e-51 172.5 0.0 1.6e-30 106.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CDO68600.1 - 2.8e-47 161.4 20.3 8.3e-22 77.8 3.1 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 CDO68600.1 - 1.7e-08 34.7 0.1 0.6 10.0 0.0 4.3 3 1 1 4 4 4 2 AAA domain T2SE PF00437.15 CDO68600.1 - 1.6e-07 30.5 3.2 0.00054 18.9 0.1 3.0 2 1 0 3 3 3 2 Type II/IV secretion system protein SMC_N PF02463.14 CDO68600.1 - 3.6e-07 29.6 0.0 0.012 14.8 1.0 3.7 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CDO68600.1 - 6.8e-07 28.8 0.8 0.012 15.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CDO68600.1 - 1.5e-06 27.5 0.9 0.047 13.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CDO68600.1 - 2.9e-05 24.1 2.7 0.23 11.4 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CDO68600.1 - 4.8e-05 23.5 0.4 6.1 7.0 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 CDO68600.1 - 8e-05 23.0 0.1 0.013 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CDO68600.1 - 0.0015 18.2 0.1 2.7 7.6 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 CDO68600.1 - 0.0044 16.8 0.4 0.014 15.2 0.1 2.0 2 0 0 2 2 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 CDO68600.1 - 0.0044 16.4 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 CDO68600.1 - 0.0061 16.8 1.2 8.3 6.7 0.1 3.5 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 CDO68600.1 - 0.0099 15.7 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Arch_ATPase PF01637.13 CDO68600.1 - 0.016 14.9 0.0 0.15 11.7 0.0 2.5 3 0 0 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 CDO68600.1 - 0.017 14.8 2.4 0.15 11.8 0.1 3.2 3 0 0 3 3 2 0 Part of AAA domain UPF0542 PF15086.1 CDO68600.1 - 0.017 14.8 1.2 7.4 6.3 0.1 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 FtsK_SpoIIIE PF01580.13 CDO68600.1 - 0.029 13.8 0.1 2.1 7.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF809 PF05663.6 CDO68600.1 - 0.035 14.0 0.3 0.13 12.1 0.1 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF809) AAA_17 PF13207.1 CDO68600.1 - 0.036 14.8 0.0 6.1 7.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CDO68600.1 - 0.047 13.6 0.1 0.92 9.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 CDO68600.1 - 0.057 13.2 0.1 9.6 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CDO68600.1 - 0.059 12.4 0.4 7 5.6 0.0 2.7 2 1 0 2 2 2 0 Zeta toxin RseC_MucC PF04246.7 CDO68600.1 - 0.099 12.2 0.0 0.39 10.2 0.0 2.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Miro PF08477.8 CDO68600.1 - 0.16 12.4 0.1 29 5.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 CDO68600.1 - 0.19 11.6 0.2 5.1 7.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 CDO68601.1 - 1.2e-50 171.3 0.0 7.9e-30 103.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CDO68601.1 - 4.5e-49 167.3 23.2 3.6e-24 85.6 7.8 3.3 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 CDO68601.1 - 8.8e-10 39.0 0.1 0.51 10.2 0.0 4.4 3 1 0 3 3 3 3 AAA domain T2SE PF00437.15 CDO68601.1 - 8.8e-09 34.6 0.2 0.00039 19.3 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 CDO68601.1 - 3.3e-08 33.1 0.1 0.0037 16.6 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CDO68601.1 - 7.7e-07 28.5 0.8 0.039 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CDO68601.1 - 1.3e-06 27.8 0.8 0.028 13.6 0.1 4.6 3 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CDO68601.1 - 5.6e-05 23.5 0.2 0.014 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CDO68601.1 - 0.00012 22.1 1.7 0.2 11.6 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain Arch_ATPase PF01637.13 CDO68601.1 - 0.00019 21.1 0.0 0.006 16.3 0.0 3.0 3 1 0 3 3 2 1 Archaeal ATPase AAA_22 PF13401.1 CDO68601.1 - 0.00021 21.4 0.3 5.9 7.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 CDO68601.1 - 0.00035 20.3 0.2 0.5 10.0 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CDO68601.1 - 0.0017 17.8 0.1 0.59 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 CDO68601.1 - 0.0025 17.5 0.7 0.093 12.4 0.1 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 CDO68601.1 - 0.0039 18.0 0.2 0.7 10.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 CDO68601.1 - 0.01 15.6 0.1 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 CDO68601.1 - 0.01 16.1 0.3 3.9 7.7 0.2 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CDO68601.1 - 0.011 15.5 0.3 0.031 14.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 CDO68601.1 - 0.025 13.7 0.2 4 6.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.4 CDO68601.1 - 0.034 12.7 1.4 0.47 9.0 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 CDO68601.1 - 0.036 13.7 0.5 0.97 9.1 0.0 2.9 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 CDO68601.1 - 0.039 13.4 0.3 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 CDO68601.1 - 0.042 13.7 1.0 7 6.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CDO68601.1 - 0.043 13.7 0.5 0.61 10.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0542 PF15086.1 CDO68601.1 - 0.073 12.8 1.1 8.3 6.2 0.2 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Miro PF08477.8 CDO68601.1 - 0.17 12.3 0.2 24 5.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 CDO68601.1 - 0.18 11.7 0.2 4.5 7.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 CDO68601.1 - 0.19 10.8 0.1 7.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Pox_A32 PF04665.7 CDO68601.1 - 0.39 9.9 0.9 13 5.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein DUF809 PF05663.6 CDO68601.1 - 3.4 7.6 4.0 8.8 6.2 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF809) bZIP_2 PF07716.10 CDO68602.1 - 0.00044 20.0 15.8 0.0021 17.8 1.4 2.7 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.16 CDO68602.1 - 0.00046 20.0 12.8 0.0021 18.0 2.1 2.3 2 0 0 2 2 2 2 bZIP transcription factor MerR_2 PF13591.1 CDO68602.1 - 0.059 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF972 PF06156.8 CDO68602.1 - 0.062 13.6 0.5 0.11 12.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Med9 PF07544.8 CDO68602.1 - 0.1 12.3 5.1 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SPX PF03105.14 CDO68602.1 - 0.15 11.7 4.2 0.32 10.7 1.6 1.9 2 0 0 2 2 2 0 SPX domain Kinetocho_Slk19 PF12709.2 CDO68602.1 - 1.1 9.3 4.7 0.43 10.6 1.2 1.8 2 0 0 2 2 2 0 Central kinetochore-associated HALZ PF02183.13 CDO68602.1 - 2.7 7.7 6.4 0.64 9.7 2.1 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper NAM-associated PF14303.1 CDO68602.1 - 3.4 7.9 11.2 0.056 13.7 3.0 1.5 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain DivIC PF04977.10 CDO68602.1 - 6.2 6.3 7.4 12 5.4 1.2 2.2 2 0 0 2 2 2 0 Septum formation initiator Transaldolase PF00923.14 CDO68603.1 - 1.1e-19 70.7 0.0 2.2e-19 69.7 0.0 1.5 1 1 0 1 1 1 1 Transaldolase Hydrolase_like PF13242.1 CDO68604.1 - 1.4e-17 63.1 0.0 2.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CDO68604.1 - 5.2e-15 55.1 0.6 1.9e-08 34.1 0.0 2.7 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDO68604.1 - 3.6e-10 40.6 0.0 5.4e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CDO68604.1 - 0.00069 19.8 0.0 0.02 15.1 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 CDO68604.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Ribosomal_L34e PF01199.13 CDO68605.1 - 4e-39 132.7 3.4 5.5e-39 132.2 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 CDO68605.1 - 0.21 11.2 3.4 7.1 6.3 0.2 2.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Nop53 PF07767.6 CDO68606.1 - 2.8e-61 207.6 27.7 1.9e-54 185.1 9.5 2.9 2 1 1 3 3 3 2 Nop53 (60S ribosomal biogenesis) BOP1NT PF08145.7 CDO68606.1 - 4.8e-06 26.5 0.6 4.8e-06 26.5 0.4 2.0 2 1 0 2 2 2 1 BOP1NT (NUC169) domain Chorion_2 PF03964.10 CDO68606.1 - 2.3 8.8 0.0 2.3 8.8 0.0 3.4 2 1 1 3 3 3 0 Chorion family 2 Usp PF00582.21 CDO68607.1 - 9e-15 55.1 0.0 1.2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF4078 PF13300.1 CDO68608.1 - 1.2 9.2 11.3 2.7 8.1 7.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4078) RCC1 PF00415.13 CDO68609.1 - 1.5e-26 92.3 3.7 2.7e-06 27.4 0.0 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDO68609.1 - 4e-18 64.5 21.6 4.3e-09 35.7 0.4 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat MFS_1 PF07690.11 CDO68611.1 - 4.3e-33 114.4 35.0 5.6e-33 114.1 23.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Neurensin PF14927.1 CDO68611.1 - 0.18 11.1 1.0 0.4 10.0 0.1 2.0 2 0 0 2 2 2 0 Neurensin FHA PF00498.21 CDO68612.1 - 5.1e-06 26.5 0.0 8.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Alginate_lyase PF05426.7 CDO68614.1 - 1.6e-68 230.9 5.7 7.8e-68 228.7 2.7 2.0 2 0 0 2 2 2 2 Alginate lyase Glyco_hydro_28 PF00295.12 CDO68615.1 - 5.3e-53 180.0 11.4 6.8e-53 179.7 7.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 CDO68615.1 - 3.7e-05 23.5 25.9 0.00025 20.8 17.9 2.1 1 1 0 1 1 1 1 Right handed beta helix region Fungal_trans PF04082.13 CDO68616.1 - 3.9e-12 45.5 0.0 7.6e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CDO68616.1 - 1.7e-06 27.8 9.4 3e-06 27.0 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 CDO68617.1 - 5.5e-24 85.3 0.0 2.3e-23 83.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CDO68617.1 - 7.3e-20 70.6 0.0 1.9e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CDO68617.1 - 1e-10 41.0 0.0 8.7e-09 34.7 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CDO68617.1 - 5.3e-09 36.2 0.0 1.3e-05 25.2 0.0 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CDO68617.1 - 0.003 17.6 0.6 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 CDO68617.1 - 0.011 15.7 0.1 0.4 10.7 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CDO68617.1 - 0.022 15.1 0.2 0.23 11.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO68617.1 - 0.07 12.8 0.1 4.9 6.8 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 CDO68617.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Transp_cyt_pur PF02133.10 CDO68618.1 - 4e-18 65.2 32.2 1e-09 37.5 19.4 2.8 2 1 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Pyr_redox_3 PF13738.1 CDO68618.1 - 0.00023 21.2 0.1 0.0004 20.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S24 PF00717.18 CDO68619.1 - 6.1e-08 32.1 0.0 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HLH PF00010.21 CDO68620.1 - 2.3e-06 27.1 0.4 6e-06 25.8 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.4 CDO68620.1 - 0.023 14.6 0.8 0.057 13.4 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) Gpi1 PF05024.10 CDO68621.1 - 3.8e-50 170.2 5.8 5.9e-50 169.5 4.0 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) AMP-binding PF00501.23 CDO68622.1 - 1.6e-74 250.8 0.1 1.1e-52 178.8 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CDO68622.1 - 5.8e-14 52.7 0.5 2e-13 51.0 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Phi-29_GP16_7 PF06720.6 CDO68622.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 COPI_assoc PF08507.5 CDO68623.1 - 0.002 17.7 2.8 0.0025 17.4 0.3 1.9 2 0 0 2 2 2 1 COPI associated protein COX15-CtaA PF02628.10 CDO68623.1 - 0.034 13.0 2.1 0.064 12.1 1.3 1.3 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein MpPF26 PF07666.6 CDO68623.1 - 0.15 11.9 2.2 0.16 11.8 0.5 1.7 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF2975 PF11188.3 CDO68623.1 - 1.9 8.2 8.0 6.3 6.5 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) CCDC92 PF14916.1 CDO68624.1 - 0.0098 15.4 0.3 0.039 13.5 0.2 2.1 1 0 0 1 1 1 1 Coiled-coil domain of unknown function DUF1664 PF07889.7 CDO68624.1 - 0.025 14.3 7.5 1.4 8.7 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) GldM_N PF12081.3 CDO68624.1 - 0.044 13.2 0.6 1.8 8.0 0.1 2.8 2 1 0 3 3 3 0 GldM N-terminal domain DUF948 PF06103.6 CDO68624.1 - 0.14 11.9 1.0 86 3.0 0.0 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) UCH PF00443.24 CDO68625.1 - 1.1e-49 168.9 0.0 1.6e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDO68625.1 - 7.1e-14 51.9 0.0 2.2e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Fibrillarin PF01269.12 CDO68626.1 - 1.3e-107 357.9 0.0 2e-107 357.3 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin PMT PF02366.13 CDO68626.1 - 8.2e-77 257.8 18.7 8.2e-77 257.8 13.0 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CDO68626.1 - 1e-31 109.9 0.1 1.5e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 MIR domain GCD14 PF08704.5 CDO68626.1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CDO68626.1 - 0.055 12.9 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 CDO68626.1 - 0.32 10.5 0.0 2.1 7.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 CDO68627.1 - 2.1e-16 59.6 44.0 2.1e-16 59.6 30.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CDO68627.1 - 0.0026 17.4 3.4 0.008 15.9 0.7 2.7 2 0 0 2 2 2 1 MFS_1 like family F-box-like PF12937.2 CDO68628.1 - 0.0032 17.1 2.7 0.0082 15.8 1.8 1.7 1 0 0 1 1 1 1 F-box-like MitMem_reg PF13012.1 CDO68630.1 - 5.9e-37 126.2 0.5 1.4e-36 125.0 0.3 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CDO68630.1 - 7.1e-22 77.2 0.0 1.9e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease COX4 PF02936.9 CDO68631.1 - 8.5e-33 113.0 0.0 1e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Unstab_antitox PF09720.5 CDO68631.1 - 0.39 10.4 3.2 17 5.1 0.9 2.3 2 0 0 2 2 2 0 Putative addiction module component zf-CCHC PF00098.18 CDO68632.1 - 5.7e-53 174.4 59.7 3.2e-09 36.2 0.7 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CDO68632.1 - 6.4e-11 41.7 45.6 0.029 14.0 0.8 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 CDO68632.1 - 7.1e-08 32.0 41.4 0.022 14.5 1.0 7.2 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 CDO68632.1 - 0.0024 17.4 52.5 0.03 13.9 1.2 7.3 6 1 1 7 7 7 5 Zinc knuckle zf-CCHC_2 PF13696.1 CDO68632.1 - 0.035 13.5 40.4 0.25 10.8 0.3 7.2 3 2 4 7 7 7 0 Zinc knuckle ATP-synt_Eps PF04627.8 CDO68633.1 - 1.3e-22 79.1 2.8 1.7e-22 78.7 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ras PF00071.17 CDO68634.1 - 8e-29 100.1 0.0 2.9e-18 65.7 0.0 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 CDO68634.1 - 6.9e-05 23.3 0.0 0.0049 17.3 0.0 2.2 1 1 1 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CDO68634.1 - 0.012 15.0 0.0 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDO68634.1 - 0.11 12.3 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.24 CDO68635.1 - 4.8e-44 149.8 2.5 1.5e-43 148.1 0.4 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO68635.1 - 5.3e-27 93.5 0.3 2e-26 91.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CDO68635.1 - 0.00082 19.0 0.2 0.0025 17.5 0.1 1.9 1 1 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CDO68635.1 - 0.00093 19.0 0.0 0.0021 17.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CDO68635.1 - 0.006 16.1 0.3 0.018 14.6 0.1 1.9 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 CDO68635.1 - 0.012 14.9 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain tRNA-synt_1b PF00579.20 CDO68635.1 - 0.03 13.4 0.0 0.083 11.9 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.1 CDO68635.1 - 0.035 14.2 0.1 0.12 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 CDO68635.1 - 0.053 13.2 0.1 0.28 10.9 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain CMS1 PF14617.1 CDO68635.1 - 0.055 12.5 0.0 0.15 11.0 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF382 PF04037.8 CDO68636.1 - 1.2e-61 206.1 0.4 1.2e-61 206.1 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 CDO68636.1 - 5.8e-19 67.2 6.8 1.2e-18 66.2 4.7 1.5 1 0 0 1 1 1 1 PSP HMGL-like PF00682.14 CDO68637.1 - 1.5e-58 198.2 0.0 2.4e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 CDO68637.1 - 1.4e-46 157.5 0.0 5.8e-22 77.9 0.0 2.6 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain Metallophos PF00149.23 CDO68638.1 - 3.8e-10 39.5 0.1 6.5e-10 38.7 0.1 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDO68638.1 - 0.022 14.5 0.1 0.053 13.3 0.1 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain tRNA-synt_1c PF00749.16 CDO68639.1 - 2.7e-102 341.6 0.0 5.3e-102 340.6 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CDO68639.1 - 1.1e-33 116.3 0.9 2e-33 115.4 0.6 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.20 CDO68639.1 - 2.4e-06 27.4 0.0 5.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO68639.1 - 3.4e-06 27.4 0.4 1.2e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO68639.1 - 7e-06 25.8 0.2 1.7e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UBN2_3 PF14244.1 CDO68640.1 - 3.8e-09 36.2 0.0 4.3e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO68640.1 - 0.04 13.3 0.1 0.087 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) PRCH PF03967.8 CDO68640.1 - 0.082 12.4 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region ADH_zinc_N PF00107.21 CDO68641.1 - 1.3e-11 44.1 0.2 2.7e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO68641.1 - 4e-06 26.5 0.2 2.7e-05 23.8 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CDO68641.1 - 0.00023 22.0 0.0 0.00047 21.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box-like PF12937.2 CDO68642.1 - 0.017 14.8 0.1 0.12 12.0 0.0 2.5 2 0 0 2 2 2 0 F-box-like Sec10 PF07393.6 CDO68647.1 - 4e-133 445.1 0.0 1e-132 443.7 0.0 1.5 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 CDO68647.1 - 7.3e-05 22.3 0.1 0.00021 20.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO68647.1 - 8.2e-05 22.2 0.8 0.00017 21.2 0.1 1.9 2 0 0 2 2 2 1 F-box-like ABC1 PF03109.11 CDO68648.1 - 1.5e-26 92.6 0.1 2.7e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 CDO68648.1 - 0.00063 19.5 1.9 0.028 14.1 1.3 3.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family GIT_SHD PF08518.6 CDO68649.1 - 8.1e-26 89.0 3.0 2.6e-14 52.2 1.1 3.1 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT E1-E2_ATPase PF00122.15 CDO68649.1 - 6.6e-19 67.8 0.0 1.5e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CDO68649.1 - 9.2e-13 48.7 0.0 5.7e-12 46.2 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDO68649.1 - 2e-12 46.9 0.0 5.3e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 CDO68649.1 - 9.2e-10 39.2 1.0 3.8e-08 34.0 0.7 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDO68649.1 - 0.0038 16.8 0.8 0.014 14.9 0.2 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_13 PF13166.1 CDO68649.1 - 3.2 6.1 10.9 6.7 5.0 7.5 1.4 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 CDO68649.1 - 8.2 4.1 12.1 19 2.9 8.4 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Aldo_ket_red PF00248.16 CDO68650.1 - 1e-59 201.7 0.0 1.2e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family COesterase PF00135.23 CDO68651.1 - 2.4e-07 29.8 0.0 3.3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Terpene_synth_C PF03936.11 CDO68654.1 - 1.3e-13 50.8 0.0 1.8e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.11 CDO68655.1 - 3.4e-14 52.3 12.9 4.6e-14 51.9 8.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO68655.1 - 0.046 12.2 6.4 0.071 11.6 4.4 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter zf-C2H2 PF00096.21 CDO68656.1 - 0.0071 16.6 0.4 0.015 15.5 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO68656.1 - 0.09 13.1 0.4 0.24 11.7 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger double domain Sugar_tr PF00083.19 CDO68657.1 - 9.4e-76 255.1 18.0 9.4e-76 255.1 12.5 1.7 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CDO68657.1 - 4.3e-15 55.2 47.9 7.6e-14 51.1 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG11 PF10377.4 CDO68658.1 - 7.3e-33 113.2 0.0 2.2e-32 111.6 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein 11 GAS PF13851.1 CDO68658.1 - 0.0045 16.1 10.2 0.0045 16.1 7.1 5.1 2 2 3 5 5 5 2 Growth-arrest specific micro-tubule binding DUF4419 PF14388.1 CDO68660.1 - 2e-102 342.4 0.0 2.4e-102 342.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) NTP_transf_5 PF14907.1 CDO68660.1 - 0.022 14.0 0.2 0.65 9.2 0.0 2.8 2 1 0 2 2 2 0 Uncharacterised nucleotidyltransferase PapB PF03333.8 CDO68660.1 - 0.18 11.6 0.3 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Adhesin biosynthesis transcription regulatory protein XhlA PF10779.4 CDO68661.1 - 3.2e-07 30.1 9.5 8.9e-07 28.7 0.9 3.1 3 0 0 3 3 3 1 Haemolysin XhlA FlaC_arch PF05377.6 CDO68661.1 - 4.4e-05 23.2 6.2 0.0003 20.6 0.7 2.9 2 1 0 2 2 2 1 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 CDO68661.1 - 9.2e-05 22.2 8.4 0.00058 19.7 5.8 2.1 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.2 CDO68661.1 - 0.00069 19.0 0.7 0.00069 19.0 0.5 2.2 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain DUF948 PF06103.6 CDO68661.1 - 0.003 17.3 11.3 0.33 10.8 1.2 2.9 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.15 CDO68661.1 - 0.0037 16.9 0.8 0.0037 16.9 0.5 3.2 2 1 1 3 3 2 1 Prefoldin subunit Med4 PF10018.4 CDO68661.1 - 0.0056 16.1 10.1 0.12 11.7 0.0 3.2 3 0 0 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 IFT57 PF10498.4 CDO68661.1 - 0.0076 15.0 0.7 0.0076 15.0 0.5 2.1 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 LPP PF04728.8 CDO68661.1 - 0.011 15.5 2.7 0.15 11.8 0.4 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 CDO68661.1 - 0.011 14.9 7.9 0.17 11.0 0.7 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2730 PF10805.3 CDO68661.1 - 0.011 15.4 3.3 0.011 15.4 2.3 2.8 2 1 0 3 3 2 0 Protein of unknown function (DUF2730) AAA_13 PF13166.1 CDO68661.1 - 0.014 13.9 2.7 0.017 13.6 0.3 1.8 2 0 0 2 2 2 0 AAA domain ING PF12998.2 CDO68661.1 - 0.031 14.5 2.1 0.16 12.2 0.1 2.4 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.7 CDO68661.1 - 0.032 14.0 5.4 0.56 10.0 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.7 CDO68661.1 - 0.054 13.8 0.7 0.054 13.8 0.5 3.4 3 0 0 3 3 2 0 SlyX Lectin_N PF03954.9 CDO68661.1 - 0.068 12.5 9.8 0.6 9.5 1.3 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain bZIP_1 PF00170.16 CDO68661.1 - 0.086 12.8 3.7 4.1 7.4 0.4 2.4 2 0 0 2 2 2 0 bZIP transcription factor Fib_alpha PF08702.5 CDO68661.1 - 0.098 12.7 10.2 0.13 12.4 3.1 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ORF6C PF10552.4 CDO68661.1 - 0.13 11.9 2.2 1.6 8.4 0.1 2.5 2 0 0 2 2 2 0 ORF6C domain IncA PF04156.9 CDO68661.1 - 0.15 11.6 9.3 0.65 9.5 0.6 2.7 2 1 0 2 2 2 0 IncA protein NPV_P10 PF05531.7 CDO68661.1 - 0.17 12.1 11.1 0.31 11.3 0.1 3.0 3 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.15 CDO68661.1 - 0.34 9.9 14.1 0.061 12.4 3.6 2.8 2 1 0 2 2 2 0 Tropomyosin Viral_P18 PF04521.8 CDO68661.1 - 0.36 10.2 3.8 1.2 8.6 0.6 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Bacillus_HBL PF05791.6 CDO68661.1 - 0.42 9.9 7.0 4.3 6.6 0.4 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Ax_dynein_light PF10211.4 CDO68661.1 - 0.45 10.3 12.8 2.5 7.9 0.6 3.1 2 1 1 3 3 3 0 Axonemal dynein light chain FUSC PF04632.7 CDO68661.1 - 0.46 8.8 6.3 0.46 8.8 3.6 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF4164 PF13747.1 CDO68661.1 - 0.52 10.4 7.2 0.5 10.5 2.8 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4164) TMCO5 PF14992.1 CDO68661.1 - 0.63 9.1 10.5 0.11 11.6 2.6 2.5 2 1 0 2 2 2 0 TMCO5 family DUF1515 PF07439.6 CDO68661.1 - 0.74 9.6 7.5 0.99 9.2 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DASH_Dad2 PF08654.5 CDO68661.1 - 0.79 9.7 9.9 1.1 9.3 0.0 3.4 3 1 0 3 3 2 0 DASH complex subunit Dad2 APG6 PF04111.7 CDO68661.1 - 0.89 8.5 8.1 0.3 10.0 0.5 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 FCP1_C PF09309.5 CDO68661.1 - 0.9 8.7 10.4 0.63 9.2 4.9 2.2 2 1 1 3 3 3 0 FCP1, C-terminal Transposase_22 PF02994.9 CDO68661.1 - 0.99 7.8 8.8 0.019 13.4 1.2 1.7 2 0 0 2 2 2 0 L1 transposable element RmuC PF02646.11 CDO68661.1 - 1.5 7.6 11.1 0.11 11.3 0.4 2.8 2 1 1 3 3 3 0 RmuC family DUF4407 PF14362.1 CDO68661.1 - 1.6 7.6 7.9 1.6 7.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Uds1 PF15456.1 CDO68661.1 - 2.6 8.0 9.5 7.9 6.4 0.1 3.1 2 1 1 3 3 3 0 Up-regulated During Septation Seryl_tRNA_N PF02403.17 CDO68661.1 - 3.9 7.5 8.8 0.35 10.8 0.8 2.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DASH_Dam1 PF08653.5 CDO68661.1 - 4.4 7.1 5.3 6.5 6.5 0.7 2.9 1 1 2 3 3 3 0 DASH complex subunit Dam1 DUF16 PF01519.11 CDO68661.1 - 4.6 7.5 15.9 4.7 7.4 1.8 3.0 2 1 1 3 3 3 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.3 CDO68661.1 - 4.6 7.1 14.5 1.6 8.6 0.2 3.2 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 CDO68661.1 - 5.3 7.4 12.1 8.8 6.7 0.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF2360 PF10152.4 CDO68661.1 - 5.5 7.2 17.6 1.3e+02 2.7 10.6 2.7 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Fmp27_WPPW PF10359.4 CDO68661.1 - 6 5.1 11.6 0.54 8.6 0.8 2.7 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain EMP24_GP25L PF01105.19 CDO68661.1 - 6.1 6.5 13.9 2.7 7.6 0.2 2.8 2 1 0 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF4419 PF14388.1 CDO68662.1 - 6.5e-68 229.1 0.1 2.5e-57 194.3 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) DUF4419 PF14388.1 CDO68663.1 - 5.1e-92 308.2 0.0 1.1e-89 300.6 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) ATG16 PF08614.6 CDO68664.1 - 0.00012 21.9 2.1 0.00017 21.4 1.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Tropomyosin PF00261.15 CDO68664.1 - 0.00029 19.9 3.1 0.00044 19.4 2.2 1.2 1 0 0 1 1 1 1 Tropomyosin PspA_IM30 PF04012.7 CDO68664.1 - 0.00035 19.9 2.0 0.00046 19.6 1.0 1.4 1 1 0 1 1 1 1 PspA/IM30 family SlyX PF04102.7 CDO68664.1 - 0.00077 19.7 0.7 0.00077 19.7 0.5 1.9 2 0 0 2 2 1 1 SlyX LPP PF04728.8 CDO68664.1 - 0.0011 18.6 3.7 0.02 14.7 0.3 3.1 1 1 2 3 3 3 1 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.2 CDO68664.1 - 0.0013 18.6 3.7 0.0028 17.5 2.6 1.5 1 1 0 1 1 1 1 Tropomyosin like PEARLI-4 PF05278.7 CDO68664.1 - 0.0021 17.4 1.9 0.0031 16.9 1.4 1.2 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) TMF_DNA_bd PF12329.3 CDO68664.1 - 0.0044 16.8 3.0 0.0071 16.1 2.1 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Lge1 PF11488.3 CDO68664.1 - 0.0061 16.7 5.8 0.35 11.0 4.0 2.4 1 1 0 1 1 1 1 Transcriptional regulatory protein LGE1 XhlA PF10779.4 CDO68664.1 - 0.0073 16.1 1.0 0.014 15.2 0.7 1.6 1 0 0 1 1 1 1 Haemolysin XhlA IncA PF04156.9 CDO68664.1 - 0.0087 15.6 0.8 0.012 15.2 0.6 1.2 1 0 0 1 1 1 1 IncA protein DUF16 PF01519.11 CDO68664.1 - 0.0093 16.1 1.4 0.015 15.4 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF16 BLOC1_2 PF10046.4 CDO68664.1 - 0.011 15.9 5.7 0.049 13.7 3.9 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2730 PF10805.3 CDO68664.1 - 0.011 15.5 5.3 0.02 14.5 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) ADIP PF11559.3 CDO68664.1 - 0.011 15.6 2.3 0.085 12.7 0.4 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 CDO68664.1 - 0.014 15.6 6.6 0.15 12.3 4.6 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Striatin PF08232.7 CDO68664.1 - 0.018 15.3 0.0 0.025 14.9 0.0 1.3 1 0 0 1 1 1 0 Striatin family FH2 PF02181.18 CDO68664.1 - 0.018 13.9 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Laminin_II PF06009.7 CDO68664.1 - 0.021 14.5 3.5 0.036 13.8 2.4 1.3 1 0 0 1 1 1 0 Laminin Domain II AAA_13 PF13166.1 CDO68664.1 - 0.025 13.0 0.4 0.033 12.6 0.3 1.1 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.8 CDO68664.1 - 0.025 14.1 4.1 0.036 13.6 2.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 CDO68664.1 - 0.029 14.1 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3373 PF11853.3 CDO68664.1 - 0.029 12.9 0.0 0.034 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) bZIP_2 PF07716.10 CDO68664.1 - 0.031 14.1 6.3 0.89 9.4 0.2 2.9 1 1 1 2 2 2 0 Basic region leucine zipper DUF3552 PF12072.3 CDO68664.1 - 0.032 13.4 3.2 0.057 12.6 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ERM PF00769.14 CDO68664.1 - 0.036 13.6 2.4 0.051 13.1 1.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1664 PF07889.7 CDO68664.1 - 0.046 13.5 4.3 0.075 12.8 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 CDO68664.1 - 0.047 12.3 2.5 0.067 11.8 1.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MtrB PF05440.7 CDO68664.1 - 0.051 13.6 0.0 0.31 11.1 0.0 2.0 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B bZIP_1 PF00170.16 CDO68664.1 - 0.064 13.2 1.5 0.19 11.7 0.8 1.9 1 1 1 2 2 2 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 CDO68664.1 - 0.086 12.8 2.9 3 7.8 0.2 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.3 CDO68664.1 - 0.092 12.4 5.0 0.24 11.1 3.4 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MbeD_MobD PF04899.7 CDO68664.1 - 0.097 12.5 0.6 0.25 11.2 0.1 1.9 1 1 1 2 2 1 0 MbeD/MobD like FlaC_arch PF05377.6 CDO68664.1 - 0.11 12.3 7.0 0.25 11.2 3.7 2.2 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 CDO68664.1 - 0.14 12.2 1.5 0.22 11.6 1.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 CDO68664.1 - 0.14 11.9 5.5 0.25 11.1 3.8 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 CDO68664.1 - 0.16 11.4 3.7 0.33 10.4 0.4 2.2 1 1 1 2 2 2 0 Septum formation initiator DegS PF05384.6 CDO68664.1 - 0.18 10.9 5.2 0.28 10.3 3.6 1.2 1 0 0 1 1 1 0 Sensor protein DegS DUF972 PF06156.8 CDO68664.1 - 0.2 12.0 2.7 0.37 11.1 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Atg14 PF10186.4 CDO68664.1 - 0.22 10.4 1.0 0.32 9.8 0.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Vac_Fusion PF02346.11 CDO68664.1 - 0.32 10.4 3.0 0.73 9.2 2.1 1.6 1 1 0 1 1 1 0 Chordopoxvirus fusion protein APG6 PF04111.7 CDO68664.1 - 0.34 9.8 2.0 0.57 9.1 1.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 AKNA PF12443.3 CDO68664.1 - 0.41 10.6 3.8 7 6.7 0.4 2.6 1 1 2 3 3 3 0 AT-hook-containing transcription factor KLRAQ PF10205.4 CDO68664.1 - 0.47 10.5 3.2 0.82 9.7 2.3 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF904 PF06005.7 CDO68664.1 - 0.93 9.8 5.6 1.5 9.1 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) GerPC PF10737.4 CDO68664.1 - 1 9.0 5.3 0.48 10.1 1.6 2.0 2 1 0 2 2 1 0 Spore germination protein GerPC DUF2360 PF10152.4 CDO68664.1 - 1.4 9.2 4.1 5.3 7.3 1.1 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Cast PF10174.4 CDO68665.1 - 7.5e-05 21.0 0.3 0.0001 20.5 0.2 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DegS PF05384.6 CDO68665.1 - 8.8e-05 21.7 0.8 0.00018 20.7 0.5 1.4 1 0 0 1 1 1 1 Sensor protein DegS Tropomyosin PF00261.15 CDO68665.1 - 0.00027 20.1 2.4 0.00047 19.3 1.7 1.3 1 0 0 1 1 1 1 Tropomyosin TMF_TATA_bd PF12325.3 CDO68665.1 - 0.00081 19.1 0.5 0.0014 18.3 0.3 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.1 CDO68665.1 - 0.0014 19.0 1.3 0.017 15.5 0.2 2.3 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.6 CDO68665.1 - 0.0022 17.8 0.4 0.0038 17.0 0.3 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Filament PF00038.16 CDO68665.1 - 0.0028 17.1 1.6 0.0044 16.5 1.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein Laminin_II PF06009.7 CDO68665.1 - 0.0028 17.4 1.3 0.0051 16.5 0.9 1.3 1 0 0 1 1 1 1 Laminin Domain II Prefoldin_2 PF01920.15 CDO68665.1 - 0.003 17.2 1.3 0.0054 16.4 0.9 1.5 1 0 0 1 1 1 1 Prefoldin subunit PEARLI-4 PF05278.7 CDO68665.1 - 0.0043 16.4 2.4 0.0067 15.8 1.7 1.2 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) NPV_P10 PF05531.7 CDO68665.1 - 0.0053 16.9 1.0 0.024 14.8 0.7 2.1 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.1 CDO68665.1 - 0.0055 16.7 0.2 0.0095 15.9 0.0 1.4 2 0 0 2 2 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin_1 PF12718.2 CDO68665.1 - 0.006 16.4 2.0 0.006 16.4 1.4 1.6 2 0 0 2 2 1 1 Tropomyosin like Baculo_PEP_C PF04513.7 CDO68665.1 - 0.0082 15.9 0.8 0.014 15.1 0.1 1.8 2 0 0 2 2 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Macoilin PF09726.4 CDO68665.1 - 0.0088 14.3 0.2 0.011 14.0 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein FliD_C PF07195.7 CDO68665.1 - 0.0091 15.3 0.3 0.019 14.2 0.2 1.5 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus BLOC1_2 PF10046.4 CDO68665.1 - 0.0097 16.0 1.0 0.02 15.0 0.7 1.5 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 CDO68665.1 - 0.012 15.4 1.0 0.024 14.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.10 CDO68665.1 - 0.012 15.4 1.7 0.022 14.5 1.0 1.7 1 1 0 1 1 1 0 Basic region leucine zipper Reo_sigmaC PF04582.7 CDO68665.1 - 0.013 14.7 1.0 0.02 14.0 0.1 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein ADIP PF11559.3 CDO68665.1 - 0.013 15.4 1.3 0.023 14.6 0.9 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 CDO68665.1 - 0.014 13.3 0.1 0.015 13.2 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lge1 PF11488.3 CDO68665.1 - 0.014 15.5 0.3 0.027 14.6 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF3373 PF11853.3 CDO68665.1 - 0.014 13.9 0.1 0.017 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TMF_DNA_bd PF12329.3 CDO68665.1 - 0.02 14.7 1.5 0.043 13.6 1.0 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 CDO68665.1 - 0.021 14.7 3.3 0.99 9.3 0.3 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) PspA_IM30 PF04012.7 CDO68665.1 - 0.022 14.1 0.4 0.04 13.2 0.3 1.4 1 0 0 1 1 1 0 PspA/IM30 family Ax_dynein_light PF10211.4 CDO68665.1 - 0.023 14.5 0.5 0.042 13.6 0.3 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain XhlA PF10779.4 CDO68665.1 - 0.026 14.4 1.4 0.05 13.5 0.9 1.5 1 0 0 1 1 1 0 Haemolysin XhlA DUF869 PF05911.6 CDO68665.1 - 0.029 12.6 0.1 0.043 12.0 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Bacillus_HBL PF05791.6 CDO68665.1 - 0.03 13.6 0.4 0.047 13.0 0.3 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF1640 PF07798.6 CDO68665.1 - 0.034 14.2 1.9 0.058 13.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Nup54 PF13874.1 CDO68665.1 - 0.036 13.7 0.2 0.077 12.6 0.1 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 GAS PF13851.1 CDO68665.1 - 0.037 13.2 2.1 0.061 12.5 1.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.6 CDO68665.1 - 0.037 14.0 1.7 0.068 13.1 1.2 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase EMP24_GP25L PF01105.19 CDO68665.1 - 0.039 13.6 0.1 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.6 CDO68665.1 - 0.043 12.4 1.3 0.068 11.8 0.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Rabaptin PF03528.10 CDO68665.1 - 0.057 13.3 0.4 0.096 12.6 0.3 1.3 1 0 0 1 1 1 0 Rabaptin DUF972 PF06156.8 CDO68665.1 - 0.06 13.7 1.4 0.14 12.5 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) RmuC PF02646.11 CDO68665.1 - 0.064 12.0 0.4 0.1 11.4 0.3 1.3 1 0 0 1 1 1 0 RmuC family DUF4472 PF14739.1 CDO68665.1 - 0.068 13.6 0.5 0.14 12.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Borrelia_P83 PF05262.6 CDO68665.1 - 0.074 11.3 0.1 0.094 10.9 0.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Spectrin PF00435.16 CDO68665.1 - 0.089 13.0 0.6 0.17 12.1 0.4 1.4 1 0 0 1 1 1 0 Spectrin repeat AAA_13 PF13166.1 CDO68665.1 - 0.1 11.0 0.2 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain Snapin_Pallidin PF14712.1 CDO68665.1 - 0.11 12.8 1.5 0.28 11.5 1.1 1.7 1 0 0 1 1 1 0 Snapin/Pallidin TBPIP PF07106.8 CDO68665.1 - 0.12 11.9 1.8 0.19 11.2 1.3 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2730 PF10805.3 CDO68665.1 - 0.12 12.0 1.8 0.44 10.2 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) MtrB PF05440.7 CDO68665.1 - 0.15 12.0 0.3 0.29 11.2 0.2 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B DivIC PF04977.10 CDO68665.1 - 0.16 11.4 0.8 0.34 10.4 0.6 1.6 1 0 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 CDO68665.1 - 0.18 10.8 1.0 0.31 10.0 0.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 CDO68665.1 - 0.18 11.9 1.1 0.42 10.7 0.6 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2408 PF10303.4 CDO68665.1 - 0.19 11.8 1.9 0.18 11.8 0.6 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2408) Atg14 PF10186.4 CDO68665.1 - 0.2 10.5 0.7 0.29 10.0 0.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMCO5 PF14992.1 CDO68665.1 - 0.23 10.5 3.8 0.12 11.4 0.7 1.7 2 0 0 2 2 2 0 TMCO5 family bZIP_1 PF00170.16 CDO68665.1 - 0.26 11.2 1.8 0.7 9.8 0.9 1.8 1 1 1 2 2 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 CDO68665.1 - 0.31 10.8 5.4 0.11 12.3 1.5 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nsp1_C PF05064.8 CDO68665.1 - 0.32 10.6 2.6 0.23 11.1 0.6 1.7 2 0 0 2 2 1 0 Nsp1-like C-terminal region SlyX PF04102.7 CDO68665.1 - 0.4 11.0 2.0 1.1 9.6 0.3 2.3 1 1 1 2 2 2 0 SlyX ORF6C PF10552.4 CDO68665.1 - 0.64 9.7 2.9 1.4 8.7 0.9 2.0 1 1 1 2 2 2 0 ORF6C domain MtrG PF04210.8 CDO68665.1 - 0.68 9.6 2.1 7.7 6.2 0.3 2.2 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Seryl_tRNA_N PF02403.17 CDO68665.1 - 0.81 9.7 6.0 0.17 11.9 1.4 1.9 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF3552 PF12072.3 CDO68665.1 - 1.1 8.4 5.8 0.29 10.3 1.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Spc24 PF08286.6 CDO68665.1 - 1.1 9.0 6.6 0.86 9.3 2.0 2.3 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Myosin_tail_1 PF01576.14 CDO68665.1 - 1.2 6.8 8.1 0.046 11.4 1.6 1.4 2 0 0 2 2 2 0 Myosin tail G-patch_2 PF12656.2 CDO68666.1 - 4.6e-27 93.6 0.1 4.6e-27 93.6 0.0 3.2 3 1 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 CDO68666.1 - 0.00048 19.8 0.7 0.0012 18.6 0.5 1.8 1 0 0 1 1 1 1 G-patch domain Sec2p PF06428.6 CDO68667.1 - 1.4e-14 53.7 10.2 1.4e-14 53.7 7.0 2.5 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DivIC PF04977.10 CDO68667.1 - 0.057 12.9 5.6 1.1 8.7 0.4 3.1 2 1 0 2 2 2 0 Septum formation initiator Herpes_UL6 PF01763.11 CDO68667.1 - 0.91 7.6 5.0 0.39 8.8 1.7 1.6 1 1 0 1 1 1 0 Herpesvirus UL6 like V_ATPase_I PF01496.14 CDO68667.1 - 1.7 6.3 7.6 2.7 5.7 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Filament PF00038.16 CDO68667.1 - 2.1 7.7 20.8 4.7 6.5 2.6 3.0 1 1 2 3 3 3 0 Intermediate filament protein Spc7 PF08317.6 CDO68667.1 - 2.5 6.6 15.8 1.1 7.9 5.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein HALZ PF02183.13 CDO68667.1 - 4.7 7.0 6.9 14 5.4 0.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.2 CDO68667.1 - 5.1 6.9 24.7 1.7 8.4 7.2 2.9 3 0 0 3 3 3 0 Tropomyosin like TMF_DNA_bd PF12329.3 CDO68667.1 - 5.6 6.8 14.6 0.17 11.7 0.5 3.5 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 CDO68667.1 - 8.8 4.6 12.3 23 3.2 8.0 1.7 1 1 0 1 1 1 0 AAA domain SIS PF01380.17 CDO68668.1 - 4.9e-62 207.3 0.1 8e-32 109.6 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CDO68668.1 - 1.7e-24 86.2 0.1 3.4e-18 65.5 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CDO68668.1 - 3e-18 66.0 0.0 6.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CDO68668.1 - 8.7e-13 48.0 0.0 2.1e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CDO68668.1 - 6.3e-08 31.6 0.0 8.8e-08 31.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 CDO68668.1 - 0.0013 18.4 0.0 0.019 14.6 0.0 2.6 1 1 0 1 1 1 1 SIS domain TENA_THI-4 PF03070.11 CDO68669.1 - 0.0028 17.4 0.0 0.01 15.5 0.0 1.8 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Sec23_trunk PF04811.10 CDO68670.1 - 3.3e-76 255.8 0.0 6.6e-76 254.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CDO68670.1 - 3.6e-24 84.1 0.1 9.1e-24 82.8 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CDO68670.1 - 1.3e-17 64.0 0.0 3.3e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CDO68670.1 - 9.8e-17 60.2 7.1 1.8e-16 59.4 4.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CDO68670.1 - 8.1e-10 38.2 0.0 1.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 CDO68670.1 - 2.4 8.0 11.3 1.8 8.5 0.9 3.1 3 0 0 3 3 3 0 WW domain MFS_1 PF07690.11 CDO68671.1 - 2.3e-20 72.6 44.2 2.1e-15 56.3 12.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF485 PF04341.7 CDO68672.1 - 0.17 11.6 0.2 0.17 11.6 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF485 RVT_1 PF00078.22 CDO68673.1 - 3.4e-28 98.4 0.0 5.4e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO68673.1 - 2e-13 50.8 0.0 3.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO68673.1 - 0.069 13.4 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_2 PF07727.9 CDO68674.1 - 2.4e-07 29.9 0.0 3.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Proteasome PF00227.21 CDO68676.1 - 2.5e-41 141.0 0.7 2.6e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit PCI_Csn8 PF10075.4 CDO68677.1 - 5.4e-32 110.5 0.0 8.6e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CDO68677.1 - 8e-32 110.4 0.0 1.4e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family AvrPphF-ORF-2 PF09143.5 CDO68677.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AvrPphF-ORF-2 Proteasome PF00227.21 CDO68678.1 - 2.9e-35 121.2 0.0 1.1e-32 112.8 0.0 2.1 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDO68678.1 - 4.2e-13 48.3 0.1 6.6e-13 47.7 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nup88 PF10168.4 CDO68679.1 - 1e-14 53.3 2.8 1e-07 30.2 0.0 3.3 3 0 0 3 3 3 2 Nuclear pore component DegT_DnrJ_EryC1 PF01041.12 CDO68679.1 - 0.33 9.9 1.2 0.56 9.1 0.8 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family 4HBT PF03061.17 CDO68680.1 - 2.5e-05 24.3 0.1 5.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily Adenine_deam_C PF13382.1 CDO68680.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain DUF4539 PF15072.1 CDO68680.1 - 0.13 11.9 0.0 0.93 9.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4539) DUF221 PF02714.10 CDO68681.1 - 2.3e-100 335.6 22.7 3.3e-100 335.1 15.7 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CDO68681.1 - 2.6e-22 79.0 0.0 2.6e-22 79.0 0.0 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CDO68681.1 - 2.7e-14 53.4 0.2 9.5e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Nsp1_C PF05064.8 CDO68682.1 - 2.3e-33 114.3 0.1 6.1e-33 112.9 0.2 1.5 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 CDO68682.1 - 1.1e-18 67.4 215.1 3.4e-10 40.1 41.6 6.9 1 1 2 3 3 3 2 Nucleoporin FG repeat region NPV_P10 PF05531.7 CDO68682.1 - 3 8.1 4.3 76 3.6 0.0 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 CDO68683.1 - 1.2e-42 145.8 40.8 1.2e-42 145.8 28.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO68683.1 - 1.2e-11 43.8 4.5 1.2e-11 43.8 3.1 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DEAD PF00270.24 CDO68684.1 - 7e-47 159.0 0.0 7.1e-46 155.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO68684.1 - 1.4e-23 82.5 0.0 3.7e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CDO68684.1 - 0.029 13.1 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 CDO68684.1 - 0.029 14.1 0.0 0.11 12.3 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PI31_Prot_N PF11566.3 CDO68685.1 - 8.4e-28 96.9 0.0 1.9e-27 95.7 0.0 1.6 2 0 0 2 2 2 1 PI31 proteasome regulator N-terminal Nucleoplasmin PF03066.10 CDO68685.1 - 3.7 7.0 7.3 7.2 6.1 5.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin Ank_4 PF13637.1 CDO68686.1 - 6.2e-31 106.2 9.3 3.2e-13 49.7 0.2 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 CDO68686.1 - 2.3e-30 104.7 0.4 2.5e-23 82.1 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDO68686.1 - 7e-29 99.1 3.8 1.7e-09 37.6 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 CDO68686.1 - 1.9e-27 93.6 2.9 1.5e-06 27.6 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 CDO68686.1 - 5.8e-21 72.4 2.7 4.7e-06 26.3 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeat FYVE PF01363.16 CDO68686.1 - 7.5e-16 57.7 10.0 7.5e-16 57.7 6.9 2.3 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 CDO68686.1 - 0.0025 17.6 3.0 0.0025 17.6 2.1 3.7 2 1 1 3 3 3 1 Ring finger domain Pex24p PF06398.6 CDO68686.1 - 0.071 11.8 0.0 0.17 10.6 0.0 1.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin FYVE_2 PF02318.11 CDO68686.1 - 2.2 8.1 9.7 0.17 11.7 2.0 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger NAD_binding_6 PF08030.7 CDO68687.1 - 2.6e-16 59.9 0.0 3.9e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CDO68687.1 - 2.8e-15 56.0 0.0 5.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 CDO68687.1 - 6.9e-11 42.3 12.8 8.1e-11 42.1 6.4 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 CDO68687.1 - 0.021 15.3 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Aminotran_1_2 PF00155.16 CDO68688.1 - 1.2e-66 225.1 0.0 1.4e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CDO68688.1 - 4.2e-08 32.6 0.0 6.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CDO68688.1 - 1e-06 27.3 0.0 2e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CDO68688.1 - 2.1e-05 23.8 0.0 3.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CDO68688.1 - 0.00038 19.3 0.0 0.0058 15.4 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DUF3410 PF11890.3 CDO68688.1 - 0.055 13.1 0.1 5.3 6.7 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3410) Sec63 PF02889.11 CDO68689.1 - 1.7e-89 300.1 0.0 2.4e-89 299.6 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CDO68689.1 - 1.3e-37 128.9 0.3 1.4e-28 99.4 0.2 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 CDO68689.1 - 1.7e-09 37.7 0.0 2.3e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CDO68689.1 - 6e-06 26.0 0.0 2.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CDO68689.1 - 3e-05 24.1 0.4 0.00087 19.4 0.1 3.3 3 0 0 3 3 3 1 AAA domain SNF2_N PF00176.18 CDO68689.1 - 0.00079 18.2 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 CDO68689.1 - 0.07 12.8 2.0 0.66 9.7 0.0 3.5 4 0 0 4 4 4 0 Part of AAA domain Xan_ur_permease PF00860.15 CDO68690.1 - 7.1e-32 110.3 26.7 2.9e-21 75.4 5.2 3.3 3 1 1 4 4 4 3 Permease family Cytochrom_C PF00034.16 CDO68691.1 - 0.056 14.2 0.5 19 6.1 0.2 2.3 2 0 0 2 2 2 0 Cytochrome c DUF106 PF01956.11 CDO68692.1 - 1.3e-38 132.2 0.0 1.6e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 EF-hand_7 PF13499.1 CDO68693.1 - 1.8e-24 85.6 2.1 2.5e-15 56.3 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CDO68693.1 - 2.4e-24 82.7 10.8 2.3e-08 32.7 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CDO68693.1 - 8.9e-20 68.7 4.4 3.3e-06 26.5 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CDO68693.1 - 2.5e-13 48.7 11.3 0.00022 20.3 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CDO68693.1 - 8.2e-13 47.7 9.9 4.5e-06 26.1 0.6 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 CDO68693.1 - 1.1e-05 25.1 5.0 0.099 12.3 0.1 3.6 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CDO68693.1 - 0.00026 20.9 0.7 0.049 13.6 0.1 3.0 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CDO68693.1 - 0.0081 16.0 1.0 0.16 11.8 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 CDO68693.1 - 0.037 13.7 0.6 20 4.9 0.0 3.3 3 0 0 3 3 3 0 EF hand S10_plectin PF03501.10 CDO68693.1 - 0.059 13.2 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_2 PF09068.6 CDO68693.1 - 0.13 12.2 0.0 1.8 8.6 0.0 2.3 2 1 0 2 2 2 0 EF hand Rep_4 PF05797.6 CDO68694.1 - 0.4 9.3 1.2 0.63 8.6 0.8 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) WD40 PF00400.27 CDO68695.1 - 2.9e-05 23.7 0.6 0.008 16.0 0.1 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF1513 PF07433.6 CDO68695.1 - 0.0085 15.0 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1513) DUF839 PF05787.8 CDO68695.1 - 0.041 12.8 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) FCP1_C PF09309.5 CDO68695.1 - 0.11 11.7 1.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 FCP1, C-terminal ATE_C PF04377.10 CDO68698.1 - 1.9e-37 128.1 0.5 1.5e-23 83.2 0.0 2.3 2 0 0 2 2 2 2 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 CDO68698.1 - 3.7e-16 58.6 1.0 6.5e-16 57.9 0.7 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Peptidase_S24 PF00717.18 CDO68698.1 - 3.3e-07 29.8 0.0 9.4e-07 28.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like Med15 PF09606.5 CDO68699.1 - 2.8 6.0 23.1 4 5.5 16.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Abhydrolase_6 PF12697.2 CDO68700.1 - 5.8e-27 95.0 0.1 7.6e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO68700.1 - 8.8e-14 51.6 0.0 1.7e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO68700.1 - 1.8e-09 37.4 0.0 1.4e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CDO68700.1 - 0.00039 19.9 0.0 0.00098 18.6 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.15 CDO68700.1 - 0.03 14.5 0.1 0.042 14.0 0.1 1.6 1 1 0 1 1 1 0 Thioesterase domain Pneumo_M2 PF07380.6 CDO68700.1 - 0.094 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Pneumovirus M2 protein Abhydrolase_6 PF12697.2 CDO68701.1 - 1.3e-25 90.6 0.1 1.7e-25 90.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO68701.1 - 5.5e-15 55.5 0.0 9.5e-14 51.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO68701.1 - 1.2e-09 38.0 0.0 4.9e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CDO68701.1 - 0.0035 16.8 0.0 0.093 12.1 0.0 2.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.15 CDO68701.1 - 0.038 14.2 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.3 CDO68701.1 - 0.067 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF1057 PF06342.7 CDO68701.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) TGS PF02824.16 CDO68702.1 - 3.7e-25 87.5 0.1 6.6e-25 86.7 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CDO68702.1 - 7.4e-17 61.3 0.0 1.7e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDO68702.1 - 2.9e-08 33.1 0.1 8.3e-08 31.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 CDO68702.1 - 0.0034 16.2 1.2 0.013 14.2 0.2 2.1 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 CDO68702.1 - 0.012 15.4 0.5 4.7 6.9 0.0 2.3 1 1 1 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 CDO68702.1 - 0.016 14.6 0.3 5 6.5 0.1 2.9 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF211 PF02680.9 CDO68702.1 - 0.019 14.7 0.1 0.059 13.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Miro PF08477.8 CDO68702.1 - 0.1 13.1 0.0 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein Ribonuc_red_sm PF00268.16 CDO68703.1 - 1.4e-106 355.6 0.3 3.1e-106 354.4 0.2 1.5 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.16 CDO68704.1 - 7e-122 405.8 2.7 8.8e-122 405.5 1.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Acetyltransf_4 PF13420.1 CDO68705.1 - 1.3e-22 80.4 0.1 1.5e-22 80.1 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CDO68705.1 - 2.5e-15 56.8 0.1 2.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO68705.1 - 5.9e-12 45.4 0.3 9.1e-12 44.8 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CDO68705.1 - 1.8e-09 37.6 0.1 2.3e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDO68705.1 - 8.1e-09 35.6 0.1 1e-08 35.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CDO68705.1 - 4.8e-08 33.0 0.0 7.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO68705.1 - 8e-06 25.5 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 CDO68705.1 - 0.0001 22.0 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 CDO68705.1 - 0.0006 19.6 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 CDO68705.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Touch receptor neuron protein Mec-17 Alg6_Alg8 PF03155.10 CDO68706.1 - 7.1e-95 318.5 34.9 1.2e-60 205.6 15.8 3.1 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family DUF2420 PF10336.4 CDO68706.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) COX14 PF14880.1 CDO68706.1 - 0.092 12.3 6.0 0.18 11.4 0.4 2.6 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Brix PF04427.13 CDO68707.1 - 1.8e-50 171.2 0.4 2.4e-50 170.8 0.3 1.1 1 0 0 1 1 1 1 Brix domain Acetyltransf_7 PF13508.1 CDO68708.1 - 2.4e-19 69.2 0.0 1.4e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO68708.1 - 1.9e-16 59.8 0.3 1.2e-07 31.7 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CDO68708.1 - 2.9e-12 46.5 0.2 1.3e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDO68708.1 - 4.7e-11 42.8 0.1 8.1e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO68708.1 - 1e-10 41.2 0.2 9.6e-07 28.4 0.0 2.7 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.1 CDO68708.1 - 1.9e-06 27.6 0.1 0.0031 17.3 0.0 2.5 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 CDO68708.1 - 0.012 15.4 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CDO68708.1 - 0.11 12.6 3.7 0.27 11.4 0.1 2.8 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain Peptidase_M18 PF02127.10 CDO68709.1 - 4.8e-147 489.9 0.0 9e-142 472.5 0.0 2.0 2 0 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CDO68709.1 - 0.00027 19.7 0.0 0.031 13.0 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase WD40 PF00400.27 CDO68710.1 - 2.5e-76 249.0 18.0 1.2e-09 37.6 0.1 11.7 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 CDO68710.1 - 7.7e-14 51.5 0.7 6.6e-13 48.5 0.5 2.2 1 1 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CDO68710.1 - 8.1e-10 37.4 1.5 0.0066 14.6 0.0 4.6 4 1 0 4 4 4 3 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 CDO68710.1 - 9.4e-06 25.0 0.0 0.59 9.6 0.0 5.3 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 CDO68710.1 - 0.00036 19.3 0.3 3.1 6.4 0.0 5.1 3 2 1 4 4 4 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 CDO68710.1 - 0.065 12.0 0.0 5 5.8 0.0 2.7 2 1 0 2 2 2 0 Coatomer WD associated region DPBB_1 PF03330.13 CDO68711.1 - 1.4e-05 24.9 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel YL1 PF05764.8 CDO68711.1 - 0.0048 16.5 2.7 0.0064 16.1 1.9 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Tn7_TnsC_Int PF11426.3 CDO68711.1 - 0.089 12.5 0.7 0.22 11.2 0.5 1.6 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC SURF2 PF05477.6 CDO68711.1 - 0.26 10.3 3.9 0.39 9.8 2.7 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Cys_Met_Meta_PP PF01053.15 CDO68712.1 - 5e-59 199.5 0.0 1.9e-58 197.6 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Acyltransferase PF01553.16 CDO68713.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase SNARE_assoc PF09335.6 CDO68714.1 - 7.9e-15 55.1 8.9 7.9e-15 55.1 6.2 2.0 1 1 1 2 2 2 1 SNARE associated Golgi protein Syntaxin-18_N PF10496.4 CDO68715.1 - 3.5e-07 29.9 1.5 8.7e-07 28.6 0.5 2.2 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DUF4094 PF13334.1 CDO68715.1 - 0.029 14.7 2.9 0.029 14.7 2.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) DUF1212 PF06738.7 CDO68715.1 - 0.17 11.3 0.4 2.3 7.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) LSM PF01423.17 CDO68716.1 - 4.1e-17 61.4 0.0 4.6e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain DUF3722 PF12519.3 CDO68718.1 - 7.1e-94 313.8 0.0 1.1e-93 313.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 CDO68718.1 - 0.00012 21.4 0.0 0.2 10.9 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic porin DEAD PF00270.24 CDO68719.1 - 1e-19 70.6 0.0 2e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDO68719.1 - 1.1e-08 35.1 0.0 7.2e-08 32.4 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CDO68719.1 - 3e-06 27.0 0.0 6.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 CDO68719.1 - 0.096 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Pex2_Pex12 PF04757.9 CDO68720.1 - 3.4e-50 170.6 5.1 4.3e-50 170.2 3.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CDO68720.1 - 4.6e-08 32.9 1.3 7e-08 32.3 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO68720.1 - 1.5e-06 27.8 1.4 2.3e-06 27.2 1.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CDO68720.1 - 4.7e-06 26.1 0.6 7.1e-06 25.5 0.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDO68720.1 - 0.0095 15.8 1.6 0.016 15.0 1.1 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CDO68720.1 - 0.01 15.4 0.7 0.016 14.8 0.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF753 PF05444.7 CDO68720.1 - 0.11 12.3 0.3 0.16 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF753) zf-RING_6 PF14835.1 CDO68720.1 - 0.18 11.6 0.5 0.32 10.8 0.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CDO68720.1 - 1.5 8.4 4.0 4.7 6.8 2.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Ank_2 PF12796.2 CDO68721.1 - 4.4e-49 164.7 3.4 8.3e-15 54.8 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CDO68721.1 - 1e-34 116.5 7.1 0.00012 21.6 0.0 7.8 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 CDO68721.1 - 2.2e-34 117.2 2.9 3.8e-10 40.0 0.0 5.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) SPX PF03105.14 CDO68721.1 - 2.1e-32 113.0 0.1 6e-20 72.1 0.0 2.4 1 1 1 2 2 2 2 SPX domain Ank_3 PF13606.1 CDO68721.1 - 1.3e-30 102.3 1.9 0.00062 19.7 0.0 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 CDO68721.1 - 7.8e-24 83.1 11.6 3.3e-06 27.1 0.1 7.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) GDPD PF03009.12 CDO68721.1 - 1.5e-13 50.8 0.0 2.7e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ABC_tran PF00005.22 CDO68722.1 - 2.8e-22 79.5 0.0 5.5e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CDO68722.1 - 1.5e-08 34.9 0.0 0.00011 22.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CDO68722.1 - 4.1e-05 22.9 0.2 0.11 11.7 0.0 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CDO68722.1 - 8.3e-05 21.8 0.0 0.0034 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.1 CDO68722.1 - 0.00013 20.6 0.0 0.072 11.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CDO68722.1 - 0.00013 22.1 0.2 0.2 11.7 0.1 3.5 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 CDO68722.1 - 0.00051 20.8 0.0 0.0012 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 CDO68722.1 - 0.0053 16.6 0.0 0.023 14.6 0.0 2.1 2 0 0 2 2 1 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 CDO68722.1 - 0.0068 16.1 0.5 0.016 14.9 0.3 1.8 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CDO68722.1 - 0.0084 16.4 0.0 0.064 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CDO68722.1 - 0.0087 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin E3_UbLigase_EDD PF11547.3 CDO68722.1 - 0.024 14.1 0.0 0.065 12.7 0.0 1.7 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD AAA_33 PF13671.1 CDO68722.1 - 0.031 14.1 0.5 0.22 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 CDO68722.1 - 0.034 13.6 0.1 0.087 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Vert_IL3-reg_TF PF06529.6 CDO68722.1 - 0.041 12.8 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor AAA_14 PF13173.1 CDO68722.1 - 0.049 13.5 0.0 2.8 7.8 0.0 3.1 4 0 0 4 4 4 0 AAA domain T2SE PF00437.15 CDO68722.1 - 0.076 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 CDO68722.1 - 0.11 11.9 0.0 0.5 9.7 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 CDO68722.1 - 0.25 11.2 1.7 0.4 10.6 0.1 2.1 2 1 1 3 3 2 0 AAA domain AAA_16 PF13191.1 CDO68722.1 - 0.56 10.1 0.0 0.56 10.1 0.0 2.7 4 0 0 4 4 4 0 AAA ATPase domain GTP_cyclohydroI PF01227.17 CDO68723.1 - 8.2e-75 250.0 0.2 1e-74 249.7 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CDO68723.1 - 0.0032 17.3 0.0 0.0083 16.0 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 CDO68723.1 - 0.061 13.1 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Tho2 PF11262.3 CDO68724.1 - 4.1e-65 219.7 0.0 8.7e-65 218.6 0.0 1.6 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 CDO68724.1 - 6.9e-26 89.8 0.1 1.9e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Glyco_hydro_88 PF07470.8 CDO68725.1 - 2.8e-17 62.7 0.3 4e-17 62.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.9 CDO68725.1 - 0.0093 15.3 2.6 0.014 14.7 1.1 1.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 MRC1 PF09444.5 CDO68726.1 - 1.8e-18 67.2 21.8 1.8e-18 67.2 15.1 4.9 5 1 0 5 5 5 1 MRC1-like domain Ribosomal_L3 PF00297.17 CDO68727.1 - 1.1e-121 405.2 8.0 1.3e-121 404.9 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PPR_2 PF13041.1 CDO68728.1 - 2.9e-10 39.9 3.2 1.2 9.1 0.1 7.1 5 1 2 7 7 7 4 PPR repeat family PPR PF01535.15 CDO68728.1 - 1.9e-06 27.4 5.9 2.1 8.4 0.0 7.0 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.2 CDO68728.1 - 0.00067 19.0 7.1 0.12 11.8 1.6 4.1 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 CDO68728.1 - 0.0012 18.9 3.9 65 4.1 0.0 6.3 6 0 0 6 6 6 0 Pentatricopeptide repeat domain AMMECR1 PF01871.12 CDO68729.1 - 1.2e-41 141.6 0.0 2.5e-40 137.3 0.0 2.0 1 1 0 1 1 1 1 AMMECR1 Ras PF00071.17 CDO68730.1 - 3.6e-44 150.0 0.0 1e-43 148.5 0.0 1.6 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CDO68730.1 - 6.9e-21 74.9 0.0 9.7e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO68730.1 - 1.2e-12 47.4 0.0 1.6e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CDO68730.1 - 1.5e-06 28.1 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CDO68730.1 - 0.00011 21.4 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CDO68730.1 - 0.00024 20.3 0.1 0.00038 19.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CDO68730.1 - 0.0033 17.5 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CDO68730.1 - 0.013 14.6 0.0 0.049 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CDO68730.1 - 0.073 12.7 0.0 0.091 12.4 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 CDO68730.1 - 0.074 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 CDO68730.1 - 0.14 11.8 0.2 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 NTPase Ribosomal_S7e PF01251.13 CDO68731.1 - 3.2e-85 284.4 3.7 3.5e-85 284.2 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_11 PF13414.1 CDO68732.1 - 1e-19 69.9 4.2 4e-11 42.4 0.3 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CDO68732.1 - 4.2e-13 48.3 5.9 4.9e-07 29.0 0.9 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDO68732.1 - 9.2e-09 34.5 8.8 2.4e-05 23.8 0.7 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDO68732.1 - 2.1e-05 25.0 2.0 0.29 11.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO68732.1 - 2.4e-05 24.5 1.8 0.00069 19.9 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDO68732.1 - 8.8e-05 22.3 2.9 0.023 14.6 0.1 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO68732.1 - 0.00031 21.0 0.4 0.035 14.7 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDO68732.1 - 0.00037 20.2 1.6 0.0051 16.6 0.3 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 CDO68732.1 - 0.0019 18.2 2.7 0.013 15.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO68732.1 - 0.0023 17.5 3.8 0.011 15.4 0.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO68732.1 - 0.0031 17.1 4.2 1.2 9.1 0.6 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 CDO68732.1 - 0.0089 15.9 0.5 1.8 8.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CDO68732.1 - 0.012 15.7 2.6 0.28 11.3 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CDO68732.1 - 0.049 13.4 0.5 0.26 11.1 0.0 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 CDO68732.1 - 0.13 12.4 0.3 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDO68732.1 - 1.9 9.1 7.7 2.4 8.7 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CCHC PF00098.18 CDO68733.1 - 0.0042 16.9 4.2 0.0042 16.9 2.9 3.0 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDO68733.1 - 0.011 15.3 0.7 0.011 15.3 0.5 3.5 3 0 0 3 3 3 0 Zinc knuckle DUF2360 PF10152.4 CDO68733.1 - 0.8 9.9 11.6 0.77 10.0 0.8 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) RVT_1 PF00078.22 CDO68734.1 - 5.9e-28 97.6 0.0 9.3e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CDO68734.1 - 3.1e-22 78.4 0.0 6.5e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 CDO68734.1 - 2.8e-12 47.1 0.0 7.2e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 CDO68734.1 - 7e-09 35.9 0.0 1.5e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PEMT PF04191.8 CDO68736.1 - 1e-51 173.4 10.2 5e-29 100.5 0.9 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase PP-binding PF00550.20 CDO68736.1 - 0.031 14.5 0.1 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphopantetheine attachment site PID PF00640.18 CDO68736.1 - 0.23 11.4 0.1 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) rve PF00665.21 CDO68738.1 - 1.7e-15 57.1 0.0 4.3e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CDO68738.1 - 4.6e-12 45.7 0.1 1e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CDO68738.1 - 9.7e-09 34.9 0.0 3.2e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDO68738.1 - 1.7e-07 31.6 0.0 5.4e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CDO68738.1 - 2.5e-06 27.4 0.0 5.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDO68738.1 - 0.00073 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 CDO68738.1 - 0.0092 16.0 0.2 0.032 14.2 0.1 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO68738.1 - 0.052 13.4 2.8 0.13 12.2 2.0 1.7 1 0 0 1 1 1 0 Zinc knuckle RVP PF00077.15 CDO68738.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 CDO68738.1 - 1.2 8.8 2.4 37 4.0 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle TLP-20 PF06088.6 CDO68738.1 - 5 6.7 4.0 14 5.2 2.8 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) UCH PF00443.24 CDO68739.1 - 4.1e-45 153.9 0.0 5.2e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDO68739.1 - 3e-18 66.2 0.0 6.5e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CDO68739.1 - 1.6e-07 30.6 0.0 3.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CDO68739.1 - 0.025 14.7 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF3886 PF13025.1 CDO68739.1 - 0.76 9.7 5.1 1.8 8.5 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Bap31 PF05529.7 CDO68740.1 - 1.1e-26 93.5 2.7 1.2e-26 93.3 1.9 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DHC_N1 PF08385.7 CDO68740.1 - 0.0013 17.2 1.0 0.0014 17.0 0.7 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Stathmin PF00836.14 CDO68740.1 - 0.0043 16.6 3.0 0.0059 16.2 2.1 1.2 1 0 0 1 1 1 1 Stathmin family SID-1_RNA_chan PF13965.1 CDO68740.1 - 0.022 12.9 0.3 0.022 12.9 0.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2681 PF10883.3 CDO68740.1 - 0.045 13.9 7.7 0.34 11.1 5.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Laminin_I PF06008.9 CDO68740.1 - 0.077 12.2 6.3 0.1 11.9 4.4 1.2 1 0 0 1 1 1 0 Laminin Domain I DUF3810 PF12725.2 CDO68740.1 - 0.16 10.8 1.6 0.17 10.7 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) TMF_DNA_bd PF12329.3 CDO68740.1 - 0.34 10.7 9.0 0.49 10.2 6.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TarH PF02203.10 CDO68740.1 - 0.35 10.6 7.0 0.11 12.3 3.1 1.5 2 0 0 2 2 2 0 Tar ligand binding domain homologue FliD_N PF02465.13 CDO68740.1 - 0.48 10.8 5.6 0.91 9.9 3.6 1.7 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus HALZ PF02183.13 CDO68740.1 - 0.52 10.0 7.9 0.24 11.1 0.6 2.4 2 1 0 2 2 2 0 Homeobox associated leucine zipper Occludin_ELL PF07303.8 CDO68740.1 - 0.76 10.5 6.6 0.39 11.4 1.3 2.1 1 1 1 2 2 2 0 Occludin homology domain Aida_N PF08910.5 CDO68740.1 - 1.4 9.2 5.2 9.5 6.5 3.0 2.2 2 1 1 3 3 2 0 Aida N-terminus OmpH PF03938.9 CDO68740.1 - 2.9 7.8 11.8 1.3 8.9 6.3 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SseC PF04888.7 CDO68740.1 - 5.6 6.2 8.2 6.8 5.9 5.7 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family DivIC PF04977.10 CDO68740.1 - 9.2 5.8 11.3 28 4.2 6.3 2.5 1 1 1 2 2 2 0 Septum formation initiator p450 PF00067.17 CDO68741.1 - 8.5e-63 212.4 0.0 1e-47 162.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 CDO68742.1 - 4.3e-66 223.3 0.0 7.1e-66 222.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.16 CDO68744.1 - 1e-105 353.3 0.0 1.4e-105 352.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CDO68744.1 - 0.00012 21.2 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CDO68744.1 - 0.065 12.1 0.0 0.091 11.6 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Fes1 PF08609.5 CDO68747.1 - 1.8e-24 86.0 0.6 4.6e-24 84.7 0.4 1.7 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 CDO68747.1 - 1.3e-05 25.3 0.4 0.0087 16.3 0.2 2.9 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 CDO68747.1 - 0.024 15.1 2.4 5.3 7.6 0.2 3.8 2 2 2 4 4 4 0 HEAT-like repeat HEAT PF02985.17 CDO68747.1 - 0.064 13.3 0.2 3.5 7.9 0.1 3.0 3 0 0 3 3 3 0 HEAT repeat zf-DHHC PF01529.15 CDO68748.1 - 1.4e-34 119.0 9.8 3.1e-34 117.8 6.8 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF2975 PF11188.3 CDO68748.1 - 0.14 11.8 1.7 0.21 11.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) FYVE PF01363.16 CDO68748.1 - 3.3 7.6 10.6 11 6.0 7.4 1.8 1 1 0 1 1 1 0 FYVE zinc finger Cullin_binding PF03556.10 CDO68750.1 - 5.4e-30 103.9 0.0 2.5e-21 75.9 0.0 2.2 1 1 1 2 2 2 2 Cullin binding UBA_4 PF14555.1 CDO68750.1 - 8e-09 34.8 0.0 1.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBN2_2 PF14227.1 CDO68752.1 - 6e-19 67.7 0.0 1.3e-18 66.7 0.0 1.5 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO68752.1 - 6.5e-19 67.8 0.0 9.2e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO68752.1 - 5.6e-12 45.4 0.0 8.7e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO68752.1 - 2.3e-07 30.3 2.8 4.1e-07 29.6 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDO68752.1 - 0.0053 16.4 0.3 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CDO68752.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_2 PF13696.1 CDO68752.1 - 0.023 14.1 1.0 0.05 13.1 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1759 PF03564.10 CDO68752.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) zf-CCHC_6 PF15288.1 CDO68752.1 - 0.24 11.0 1.6 0.46 10.1 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle ASF1_hist_chap PF04729.8 CDO68755.1 - 8.5e-59 197.5 0.0 1.1e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF3123 PF11321.3 CDO68755.1 - 0.074 13.3 0.4 0.13 12.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF1664 PF07889.7 CDO68756.1 - 0.0017 18.1 0.1 0.0027 17.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) ATG16 PF08614.6 CDO68756.1 - 0.035 13.9 13.3 0.28 10.9 8.6 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.1 CDO68756.1 - 0.069 13.1 0.7 0.069 13.1 0.5 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 LLC1 PF14945.1 CDO68756.1 - 0.073 13.3 1.2 0.22 11.8 0.1 2.1 2 1 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Macoilin PF09726.4 CDO68756.1 - 0.081 11.2 9.9 0.1 10.8 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Bap31 PF05529.7 CDO68756.1 - 0.28 10.6 6.8 25 4.2 4.7 2.3 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like GAS PF13851.1 CDO68756.1 - 0.29 10.3 13.1 0.18 10.9 1.9 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 CDO68756.1 - 0.29 10.5 11.8 0.98 8.8 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) AAA_13 PF13166.1 CDO68756.1 - 0.36 9.2 4.4 0.54 8.6 3.0 1.2 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.6 CDO68756.1 - 0.44 10.4 2.1 29 4.6 0.1 3.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) K-box PF01486.12 CDO68756.1 - 0.45 10.3 6.2 3 7.6 0.2 3.2 2 1 1 3 3 3 0 K-box region DUF2353 PF09789.4 CDO68756.1 - 0.51 9.5 10.4 1.8 7.7 7.2 1.8 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) bZIP_1 PF00170.16 CDO68756.1 - 0.55 10.2 9.4 2.1 8.3 0.2 3.5 3 0 0 3 3 3 0 bZIP transcription factor DUF3323 PF11796.3 CDO68756.1 - 0.79 9.0 13.3 1.1 8.5 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) ADIP PF11559.3 CDO68756.1 - 1 9.2 10.6 0.091 12.6 1.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 CDO68756.1 - 1.2 7.4 5.6 1.3 7.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Vma12 PF11712.3 CDO68756.1 - 1.5 8.5 5.3 6.9 6.3 1.1 2.4 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RRF PF01765.14 CDO68756.1 - 1.8 8.0 5.3 0.31 10.4 0.1 2.1 2 1 1 3 3 3 0 Ribosome recycling factor TBPIP PF07106.8 CDO68756.1 - 1.9 7.9 7.0 0.59 9.6 0.3 2.4 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 CDO68756.1 - 2 7.3 13.7 13 4.6 9.5 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 She9_MDM33 PF05546.6 CDO68756.1 - 3.9 6.9 9.3 0.37 10.3 1.3 2.2 1 1 1 2 2 2 0 She9 / Mdm33 family Spc7 PF08317.6 CDO68756.1 - 4 5.9 10.1 2.2 6.8 0.5 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 CDO68756.1 - 4.2 6.3 13.7 9 5.2 9.2 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 CENP-Q PF13094.1 CDO68756.1 - 4.7 7.2 17.7 4.7 7.2 2.1 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_2 PF07716.10 CDO68756.1 - 4.8 7.0 16.8 5.1 7.0 0.2 3.8 4 0 0 4 4 4 0 Basic region leucine zipper TMF_DNA_bd PF12329.3 CDO68756.1 - 6.9 6.5 13.0 1.3 8.8 0.6 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 CDO68756.1 - 6.9 7.1 18.1 1.8 9.0 1.2 3.3 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 CDO68756.1 - 7.2 6.1 19.1 1.7 8.1 1.0 3.6 3 1 0 4 4 4 0 Septum formation initiator IncA PF04156.9 CDO68756.1 - 8.2 5.9 18.5 3e+02 0.8 12.8 2.1 1 1 0 1 1 1 0 IncA protein NUDIX PF00293.23 CDO68758.1 - 1.1e-09 37.9 0.0 2.5e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain WD40 PF00400.27 CDO68760.1 - 3e-07 30.0 4.2 0.00084 19.1 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 CDO68760.1 - 0.034 13.8 0.0 2.2 7.9 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 CDO68760.1 - 0.036 13.7 0.4 1.6 8.4 0.0 2.8 1 1 2 3 3 3 0 Transcription factor IIIC subunit delta N-term Glyco_hydro_16 PF00722.16 CDO68761.1 - 5.1e-06 25.8 0.0 9.4e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3678 PF12435.3 CDO68761.1 - 0.08 12.5 0.2 0.08 12.5 0.2 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3678) RVT_2 PF07727.9 CDO68762.1 - 4.2e-65 219.1 0.0 6e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO68762.1 - 1.8e-14 53.8 0.0 4.1e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CDO68762.1 - 4e-09 35.9 0.0 8.7e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CDO68762.1 - 0.003 17.0 0.0 0.0088 15.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 CDO68762.1 - 0.1 12.5 0.8 0.23 11.4 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle UBN2_3 PF14244.1 CDO68762.1 - 0.24 10.9 0.0 0.42 10.1 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type ADH_zinc_N PF00107.21 CDO68763.1 - 1.9e-31 108.2 0.5 2.7e-31 107.7 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO68763.1 - 6.9e-19 68.9 0.1 1.2e-18 68.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO68763.1 - 3e-13 49.4 0.1 1.3e-12 47.4 0.1 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GRIM-19 PF06212.7 CDO68763.1 - 0.14 11.8 0.4 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 GRIM-19 protein MFS_1 PF07690.11 CDO68764.1 - 8.4e-22 77.3 54.2 1.2e-14 53.7 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 CDO68765.1 - 6.9e-12 44.7 44.9 5.3e-11 41.8 31.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO68765.1 - 0.00041 19.0 25.4 0.004 15.7 4.7 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter Na_H_Exchanger PF00999.16 CDO68766.1 - 1.1e-69 234.8 36.2 1.4e-69 234.4 25.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 60KD_IMP PF02096.15 CDO68767.1 - 2.5e-31 108.9 6.0 3e-31 108.6 4.2 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein TPR_11 PF13414.1 CDO68768.1 - 6.7e-40 134.5 8.0 3.9e-19 68.0 0.5 6.3 4 2 2 6 6 6 5 TPR repeat TPR_1 PF00515.23 CDO68768.1 - 1.5e-30 103.4 0.0 1.1e-06 27.9 0.0 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 CDO68768.1 - 3.8e-25 85.7 6.4 1.1e-05 24.9 0.1 8.9 9 0 0 9 9 8 4 Tetratricopeptide repeat DnaJ PF00226.26 CDO68768.1 - 7.7e-24 83.2 0.2 7.7e-24 83.2 0.1 1.8 2 0 0 2 2 1 1 DnaJ domain TPR_9 PF13371.1 CDO68768.1 - 1.7e-15 56.6 9.4 6.2e-08 32.3 0.1 5.8 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 CDO68768.1 - 6.4e-15 54.8 7.7 0.00061 19.6 0.0 5.9 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CDO68768.1 - 9e-14 50.7 18.5 0.0048 17.4 0.0 8.0 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 CDO68768.1 - 5.5e-13 49.2 19.5 4.6e-08 33.5 0.4 6.7 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 CDO68768.1 - 1.2e-10 41.5 10.3 0.0041 17.4 0.0 5.7 3 3 4 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CDO68768.1 - 1.1e-08 35.0 0.4 0.00018 21.5 0.0 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CDO68768.1 - 1.5e-07 30.6 0.0 0.061 13.1 0.0 5.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDO68768.1 - 5.5e-07 29.2 0.8 0.032 14.4 0.0 6.6 7 1 0 7 7 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO68768.1 - 4.8e-06 25.9 3.8 0.74 9.7 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 CDO68768.1 - 2e-05 23.7 3.1 1.5 8.1 0.0 4.5 4 0 0 4 4 4 2 SHNi-TPR TPR_15 PF13429.1 CDO68768.1 - 0.00039 19.5 8.2 0.13 11.2 0.0 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CDO68768.1 - 0.014 15.8 9.1 0.96 10.0 0.0 5.1 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CDO68768.1 - 0.049 13.5 9.7 59 3.7 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDO68768.1 - 0.089 12.6 2.7 13 5.7 0.1 4.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CDO68768.1 - 0.44 10.7 5.5 7.7 6.7 0.1 3.0 2 1 1 3 3 2 0 Alkyl sulfatase dimerisation DUF3829 PF12889.2 CDO68768.1 - 1.3 8.1 9.4 0.076 12.2 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) DUF202 PF02656.10 CDO68769.1 - 0.099 12.8 6.3 0.58 10.4 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) SdpI PF13630.1 CDO68769.1 - 1.1 9.0 6.6 0.66 9.7 1.3 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family AA_permease_2 PF13520.1 CDO68771.1 - 1.3e-44 152.4 43.2 1.7e-44 152.0 30.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CDO68771.1 - 2.2e-07 29.5 35.9 1.7e-05 23.4 24.9 2.6 1 1 0 1 1 1 1 Amino acid permease DctQ PF04290.7 CDO68772.1 - 0.002 17.8 4.4 0.002 17.8 3.1 1.9 1 1 1 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF962 PF06127.6 CDO68772.1 - 0.046 13.6 3.3 1.6 8.6 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF962) RTA1 PF04479.8 CDO68773.1 - 6.9e-31 107.4 0.6 6.2e-19 68.3 0.4 2.2 1 1 1 2 2 2 2 RTA1 like protein DUF4131 PF13567.1 CDO68773.1 - 0.033 13.6 6.2 0.14 11.5 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF898 PF05987.8 CDO68773.1 - 0.059 12.2 4.4 0.019 13.8 0.9 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) 7TMR-DISM_7TM PF07695.6 CDO68773.1 - 0.63 9.6 7.6 0.26 10.9 1.4 2.2 2 0 0 2 2 2 0 7TM diverse intracellular signalling MARVEL PF01284.18 CDO68774.1 - 0.0046 16.7 9.6 0.0059 16.4 6.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain Abhydrolase_9_N PF15420.1 CDO68774.1 - 0.13 11.9 2.4 0.16 11.7 1.7 1.3 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Orbi_NS3 PF01616.11 CDO68774.1 - 0.16 10.9 1.0 0.2 10.5 0.7 1.1 1 0 0 1 1 1 0 Orbivirus NS3 MARVEL PF01284.18 CDO68776.1 - 8.1e-06 25.7 11.4 1.1e-05 25.2 7.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain Peptidase_U4 PF03419.8 CDO68776.1 - 0.081 11.9 2.0 0.095 11.7 1.4 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Profilin PF00235.14 CDO68778.1 - 6.6e-22 77.8 0.0 8.1e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Profilin DUF1365 PF07103.6 CDO68779.1 - 3.4e-23 82.0 0.0 4.2e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1365) Membr_traf_MHD PF10540.4 CDO68780.1 - 2.3e-18 66.3 0.0 6.6e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 CDO68780.1 - 7.7e-09 35.2 0.0 2.3e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 C2 domain Mem_trans PF03547.13 CDO68782.1 - 2.2e-33 115.1 9.6 2.9e-33 114.7 6.6 1.2 1 0 0 1 1 1 1 Membrane transport protein Trp_oprn_chp PF09534.5 CDO68782.1 - 0.031 13.8 2.2 0.1 12.2 1.5 1.8 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Polyketide_cyc2 PF10604.4 CDO68783.1 - 4.5e-09 36.5 0.0 5.7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 CDO68783.1 - 8.5e-05 22.5 0.1 0.00011 22.2 0.1 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ECSIT PF06239.6 CDO68783.1 - 0.0035 16.2 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway CAF-1_p150 PF11600.3 CDO68784.1 - 0.001 18.5 23.8 0.001 18.5 16.5 4.6 5 0 0 5 5 5 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNA_pol_I_A49 PF06870.7 CDO68785.1 - 6.9e-93 311.2 0.4 7.7e-93 311.1 0.3 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SET PF00856.23 CDO68786.1 - 3.1e-22 79.6 0.3 3.1e-22 79.6 0.2 3.4 3 2 0 3 3 3 1 SET domain SRI PF08236.6 CDO68786.1 - 4.5e-19 68.1 9.2 1.5e-18 66.5 6.4 2.0 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 CDO68786.1 - 0.011 15.2 0.1 0.045 13.2 0.0 2.1 1 1 0 1 1 1 0 TFIIS helical bundle-like domain Peptidase_S15 PF02129.13 CDO68786.1 - 0.17 11.2 0.1 0.17 11.2 0.1 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2868 PF11067.3 CDO68786.1 - 0.22 10.6 2.8 0.49 9.4 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TFIIA PF03153.8 CDO68786.1 - 0.57 10.0 12.9 0.061 13.2 5.9 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 CDO68787.1 - 5.6e-05 22.4 0.0 8.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO68787.1 - 0.029 13.4 0.0 0.059 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Kdo PF06293.9 CDO68787.1 - 0.03 13.3 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CDO68787.1 - 0.031 13.8 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase GMC_oxred_N PF00732.14 CDO68788.1 - 5.2e-46 157.1 0.0 6.7e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO68788.1 - 2.8e-36 124.9 0.1 7.2e-36 123.6 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DUF4471 PF14740.1 CDO68789.1 - 0.018 14.2 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) BP28CT PF08146.7 CDO68790.1 - 4.1e-22 78.5 3.5 1.6e-21 76.6 0.8 3.3 4 0 0 4 4 4 1 BP28CT (NUC211) domain HEAT PF02985.17 CDO68790.1 - 0.0011 18.8 4.7 0.0029 17.5 0.1 4.1 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 CDO68790.1 - 0.44 11.1 6.9 0.36 11.3 0.1 4.5 4 1 1 5 5 5 0 HEAT-like repeat U3snoRNP10 PF12397.3 CDO68791.1 - 6.6e-11 42.2 4.5 6.6e-11 42.2 3.1 3.0 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 LcrG PF07216.7 CDO68791.1 - 0.05 13.6 0.2 24 5.0 0.0 3.7 3 0 0 3 3 3 0 LcrG protein Pkinase PF00069.20 CDO68792.1 - 1.5e-39 135.6 0.0 2.2e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO68792.1 - 1.1e-28 99.9 0.0 1.5e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO68792.1 - 1.3e-06 27.6 0.0 2.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PBD PF00786.23 CDO68792.1 - 1.8e-05 25.0 0.0 7.6e-05 23.0 0.0 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain HMG_box_2 PF09011.5 CDO68793.1 - 1.8e-06 28.2 1.4 4.8e-06 26.8 0.9 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 CDO68793.1 - 2.2e-05 24.6 1.3 0.00028 21.0 0.6 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box AA_permease_N PF08403.5 CDO68793.1 - 0.086 12.1 0.1 0.39 10.0 0.0 2.1 2 0 0 2 2 2 0 Amino acid permease N-terminal AAA_10 PF12846.2 CDO68793.1 - 0.15 11.4 0.9 0.26 10.7 0.6 1.4 1 1 0 1 1 1 0 AAA-like domain WD40 PF00400.27 CDO68795.1 - 6.1e-12 44.9 0.5 7.5e-07 28.7 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1604 PF07713.8 CDO68796.1 - 1.2e-19 69.8 0.0 1.2e-19 69.8 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 CDO68796.1 - 3.9e-07 29.7 0.1 3.9e-07 29.7 0.1 2.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CDO68796.1 - 0.031 14.1 0.0 0.031 14.1 0.0 3.8 4 0 0 4 4 4 0 DExH-box splicing factor binding site YwqJ-deaminase PF14431.1 CDO68797.1 - 0.086 12.6 0.3 0.21 11.4 0.1 1.7 2 1 0 2 2 2 0 YwqJ-like deaminase AA_permease PF00324.16 CDO68798.1 - 6.8e-124 413.8 32.6 7.7e-124 413.6 22.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CDO68798.1 - 3.8e-35 121.2 37.9 4.9e-35 120.8 26.3 1.2 1 0 0 1 1 1 1 Amino acid permease Methyltransf_23 PF13489.1 CDO68799.1 - 9.2e-11 41.7 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO68799.1 - 6.5e-10 39.3 0.0 1.9e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO68799.1 - 3.7e-08 33.9 0.0 6.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO68799.1 - 1.1e-07 32.0 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO68799.1 - 1.8e-06 27.6 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO68799.1 - 2.8e-06 27.7 0.0 6.6e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO68799.1 - 0.0011 18.9 0.0 0.0057 16.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CDO68799.1 - 0.0076 15.6 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 CDO68799.1 - 0.021 15.6 0.0 0.042 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RhoGEF PF00621.15 CDO68800.1 - 3e-73 245.5 1.1 2.5e-36 125.2 0.1 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.17 CDO68800.1 - 1e-62 212.0 0.0 1.5e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 CDO68800.1 - 2.1e-19 69.8 0.0 5.5e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CDO68800.1 - 1.7e-08 34.5 0.0 1.1e-07 31.9 0.0 2.3 2 0 0 2 2 2 1 PH domain DEP PF00610.16 CDO68800.1 - 6.8e-05 22.5 0.0 0.00026 20.6 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Acetyltransf_6 PF13480.1 CDO68803.1 - 0.016 15.1 0.0 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 CDO68806.1 - 0.027 14.4 0.1 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FlxA PF14282.1 CDO68808.1 - 0.0086 16.0 0.8 0.013 15.4 0.5 1.2 1 0 0 1 1 1 1 FlxA-like protein Spectrin PF00435.16 CDO68808.1 - 0.01 16.1 2.3 0.015 15.6 1.6 1.2 1 0 0 1 1 1 0 Spectrin repeat Nnf1 PF03980.9 CDO68808.1 - 0.021 14.8 0.4 0.042 13.8 0.0 1.6 2 0 0 2 2 2 0 Nnf1 PIN_2 PF10130.4 CDO68808.1 - 0.044 13.8 0.4 0.056 13.4 0.3 1.1 1 0 0 1 1 1 0 PIN domain SPX PF03105.14 CDO68808.1 - 0.1 12.3 2.8 0.12 12.1 1.9 1.1 1 0 0 1 1 1 0 SPX domain E2R135 PF11570.3 CDO68808.1 - 0.12 12.4 3.2 0.17 11.9 2.2 1.2 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 CENP-Q PF13094.1 CDO68808.1 - 4.1 7.4 9.7 5.4 7.0 6.7 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit rve PF00665.21 CDO68809.1 - 4.9e-07 29.8 0.0 0.00063 19.8 0.0 2.6 1 1 1 2 2 2 2 Integrase core domain Chromo PF00385.19 CDO68809.1 - 1.5e-05 24.5 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CDO68809.1 - 0.00079 18.7 0.0 0.0018 17.6 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger zf-RVT PF13966.1 CDO68810.1 - 8.4e-06 26.0 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 CDO68811.1 - 7.4e-13 48.3 0.0 1.3e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO68811.1 - 2.9e-07 30.9 0.0 6.2e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 RNase H RVT_2 PF07727.9 CDO68811.1 - 0.014 14.3 0.1 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CDO68812.1 - 7.6e-12 45.1 0.3 2e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2201_N PF13203.1 CDO68812.1 - 0.11 11.7 3.9 0.31 10.1 2.3 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain zf-CCHC PF00098.18 CDO68812.1 - 0.19 11.7 0.3 0.34 10.9 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Macoilin PF09726.4 CDO68812.1 - 2.5 6.2 6.2 3.3 5.8 4.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DDE_Tnp_4 PF13359.1 CDO68813.1 - 5.1e-09 35.9 0.0 6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Acetyltransf_6 PF13480.1 CDO68814.1 - 0.012 15.6 0.1 2.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Mito_fiss_reg PF05308.6 CDO68814.1 - 0.94 8.7 8.0 1.4 8.2 5.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator FAP PF07174.6 CDO68814.1 - 1.8 7.8 10.5 2.4 7.4 7.3 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Prenyltrans PF00432.16 CDO68815.1 - 7.2e-10 38.2 0.0 1.3e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CDO68815.1 - 6.6e-05 23.2 0.0 0.0012 19.2 0.0 2.2 2 0 0 2 2 2 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 CDO68815.1 - 0.0002 21.3 0.0 0.029 14.3 0.0 2.2 2 0 0 2 2 2 2 Prenyltransferase-like Laminin_B PF00052.13 CDO68817.1 - 0.019 14.5 3.4 5.6 6.5 0.1 3.9 1 1 4 5 5 5 0 Laminin B (Domain IV) DUF3060 PF11259.3 CDO68817.1 - 2.6 7.7 13.4 3 7.5 0.2 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3060) Cellulase PF00150.13 CDO68818.1 - 0.00014 21.1 0.1 0.064 12.4 0.0 2.7 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Lipase_3 PF01764.20 CDO68819.1 - 7.9e-23 80.6 0.0 1.2e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CDO68819.1 - 0.0065 16.3 0.0 0.0087 15.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO68819.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO68819.1 - 0.022 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 CDO68819.1 - 0.039 13.3 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 Putative esterase DAGAT PF03982.8 CDO68822.1 - 3.7e-89 298.3 0.0 7e-89 297.4 0.0 1.3 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Polysacc_synt_3 PF13440.1 CDO68822.1 - 0.03 13.7 0.4 0.05 13.0 0.3 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AAA PF00004.24 CDO68823.1 - 2.2e-97 322.3 0.0 1.6e-47 161.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CDO68823.1 - 5.7e-23 80.6 0.6 8.4e-22 76.9 0.3 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 CDO68823.1 - 5.7e-14 52.3 0.0 1.4e-07 31.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CDO68823.1 - 5.7e-14 51.7 0.0 7e-06 25.2 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CDO68823.1 - 6.9e-13 48.6 0.0 1.9e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CDO68823.1 - 1.2e-12 47.7 0.8 5.6e-06 26.1 0.1 4.2 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CDO68823.1 - 2.3e-12 47.7 0.0 0.00031 21.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CDO68823.1 - 1.3e-11 44.7 0.2 0.0015 18.6 0.0 4.2 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 CDO68823.1 - 6e-11 41.8 0.0 1.3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 CDO68823.1 - 9.4e-11 42.0 0.0 0.00091 19.2 0.0 3.3 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 CDO68823.1 - 1.4e-09 37.1 0.1 0.00097 17.9 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 CDO68823.1 - 2.1e-08 34.0 0.0 0.0028 17.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CDO68823.1 - 3.3e-08 33.1 2.1 0.016 14.6 0.0 3.8 2 2 2 4 4 4 2 AAA domain Zeta_toxin PF06414.7 CDO68823.1 - 3.9e-08 32.6 0.0 0.0094 15.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 CDO68823.1 - 6.5e-08 32.2 0.0 0.0042 16.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 CDO68823.1 - 3e-07 29.8 0.3 0.025 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CDO68823.1 - 4.4e-07 30.0 0.0 0.018 15.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 CDO68823.1 - 6.3e-07 29.0 2.9 0.018 14.7 0.0 3.0 3 0 0 3 3 2 2 Part of AAA domain AAA_18 PF13238.1 CDO68823.1 - 1.4e-06 28.6 0.2 0.036 14.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain Vps4_C PF09336.5 CDO68823.1 - 1.7e-06 27.8 0.3 1.7e-05 24.6 0.1 2.7 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain KaiC PF06745.8 CDO68823.1 - 2e-06 27.1 1.3 0.49 9.4 0.0 3.4 2 1 1 3 3 3 2 KaiC AAA_24 PF13479.1 CDO68823.1 - 2.4e-06 27.2 0.1 0.065 12.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.12 CDO68823.1 - 3.4e-06 26.1 0.2 0.011 14.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 CDO68823.1 - 4.3e-06 26.6 0.0 0.0033 17.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 CDO68823.1 - 4.3e-06 25.8 0.0 0.0027 16.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CDO68823.1 - 6.8e-06 26.1 0.0 0.084 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CDO68823.1 - 7.3e-06 25.5 0.0 0.23 10.9 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 CDO68823.1 - 1.2e-05 25.5 0.0 0.045 14.0 0.0 3.7 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.13 CDO68823.1 - 2.3e-05 24.1 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 CDO68823.1 - 2.7e-05 24.2 0.0 0.37 10.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 CDO68823.1 - 3.3e-05 23.6 0.0 2.1 7.9 0.0 3.4 2 1 1 3 3 3 1 Archaeal ATPase PhoH PF02562.11 CDO68823.1 - 5.7e-05 22.4 0.2 0.2 10.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 CDO68823.1 - 0.00013 21.6 0.0 0.52 9.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 CDO68823.1 - 0.00027 20.6 0.0 0.52 9.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 CDO68823.1 - 0.0003 20.4 0.1 0.56 9.8 0.0 3.3 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 CDO68823.1 - 0.00047 19.2 0.0 0.74 8.7 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 CDO68823.1 - 0.00084 18.2 0.1 0.2 10.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.1 CDO68823.1 - 0.0015 18.1 0.1 2.7 7.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CDO68823.1 - 0.0015 18.0 0.0 0.66 9.4 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Molydop_binding PF01568.16 CDO68823.1 - 0.0021 17.8 0.1 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain T2SE PF00437.15 CDO68823.1 - 0.0042 16.0 0.0 0.37 9.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein IPT PF01745.11 CDO68823.1 - 0.0072 15.5 0.1 2 7.5 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase UFD1 PF03152.9 CDO68823.1 - 0.013 14.6 0.0 0.045 12.8 0.0 1.7 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 NTPase_1 PF03266.10 CDO68823.1 - 0.017 14.8 0.4 5.6 6.6 0.0 3.4 3 0 0 3 3 3 0 NTPase UPF0079 PF02367.12 CDO68823.1 - 0.034 13.7 0.1 3.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 CDO68823.1 - 0.066 13.0 0.0 7.1 6.4 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase Zot PF05707.7 CDO68823.1 - 0.072 12.5 0.2 17 4.8 0.1 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.9 CDO68823.1 - 0.12 11.3 0.1 2.3 7.1 0.0 2.6 2 2 1 4 4 4 0 KAP family P-loop domain KTI12 PF08433.5 CDO68823.1 - 0.12 11.5 0.0 8.3 5.5 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PIF1 PF05970.9 CDO68823.1 - 0.18 10.7 0.3 15 4.4 0.0 3.0 3 0 0 3 3 3 0 PIF1-like helicase Torsin PF06309.6 CDO68823.1 - 0.24 11.3 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Torsin CAP_GLY PF01302.20 CDO68824.1 - 7.1e-29 99.3 1.3 1.1e-28 98.6 0.9 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 CDO68824.1 - 3.9e-19 68.6 0.0 1.5e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-like domain 4HBT_2 PF13279.1 CDO68825.1 - 4.2e-15 56.2 0.0 9.1e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 CDO68825.1 - 5.3e-06 26.4 0.1 1.3e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 CDO68825.1 - 0.00057 18.9 0.1 0.021 13.8 0.0 2.3 2 1 0 2 2 2 1 Acyl-ACP thioesterase zf-C3HC4_2 PF13923.1 CDO68826.1 - 3.3e-09 36.6 10.1 3.3e-09 36.6 7.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO68826.1 - 1.3e-08 34.3 8.2 1.3e-08 34.3 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO68826.1 - 1.5e-08 34.3 10.5 1.5e-08 34.3 7.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CDO68826.1 - 1.7e-08 33.9 8.4 1.7e-08 33.9 5.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDO68826.1 - 3.5e-08 33.2 9.1 3.5e-08 33.2 6.3 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CDO68826.1 - 2.9e-05 23.6 9.5 2.9e-05 23.6 6.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CDO68826.1 - 7.2e-05 22.4 3.5 7.2e-05 22.4 2.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Phage_DsbA PF11126.3 CDO68826.1 - 0.00096 19.1 1.0 0.0016 18.4 0.7 1.3 1 0 0 1 1 1 1 Transcriptional regulator DsbA zf-RING_4 PF14570.1 CDO68826.1 - 0.008 15.7 3.8 0.008 15.7 2.6 2.5 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CDO68826.1 - 1.1 9.0 15.4 0.032 13.9 4.5 2.7 3 1 0 3 3 3 0 zf-RING of BARD1-type protein NOB1_Zn_bind PF08772.6 CDO68826.1 - 3.7 7.4 10.3 0.15 11.9 0.6 3.0 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Ran_BP1 PF00638.13 CDO68829.1 - 2e-11 43.9 0.0 2.4e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 RanBP1 domain Tape_meas_lam_C PF09718.5 CDO68829.1 - 0.13 12.1 0.1 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Thioredoxin PF00085.15 CDO68830.1 - 0.00071 19.2 0.0 0.0054 16.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin DUF4485 PF14846.1 CDO68831.1 - 0.11 12.1 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) STT3 PF02516.9 CDO68832.1 - 4.3e-133 444.7 40.4 1.5e-131 439.7 28.0 2.3 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit UBX PF00789.15 CDO68833.1 - 3.2e-10 39.9 0.3 9.5e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 UBX domain zf-C2H2_2 PF12756.2 CDO68833.1 - 0.016 15.3 0.3 0.016 15.3 0.2 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.1 CDO68833.1 - 0.16 11.6 0.3 0.4 10.4 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 CDO68833.1 - 0.19 12.0 0.3 0.44 10.9 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2 PF00096.21 CDO68833.1 - 0.2 12.0 0.2 0.38 11.1 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF572 PF04502.8 CDO68833.1 - 0.21 10.7 16.1 0.27 10.3 11.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Asp-B-Hydro_N PF05279.6 CDO68833.1 - 1.7 8.4 21.4 2.5 7.9 14.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PLRV_ORF5 PF01690.12 CDO68833.1 - 4.3 6.3 10.5 5.4 6.0 7.3 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Uds1 PF15456.1 CDO68834.1 - 0.0065 16.4 1.9 0.0065 16.4 1.3 2.5 1 1 1 2 2 2 1 Up-regulated During Septation APG6 PF04111.7 CDO68834.1 - 0.54 9.2 5.7 0.87 8.5 4.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CDO68834.1 - 1.6 8.3 6.9 0.091 12.2 0.5 2.2 3 0 0 3 3 3 0 Septum formation initiator APH PF01636.18 CDO68835.1 - 1.8e-32 112.9 0.0 2.8e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CDO68835.1 - 0.0012 18.0 0.0 0.0025 16.9 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 CDO68835.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase GMC_oxred_N PF00732.14 CDO68836.1 - 7.7e-34 117.1 0.0 6.7e-26 91.1 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO68836.1 - 3.6e-26 92.1 0.0 1.5e-25 90.1 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.7 CDO68836.1 - 4.2e-05 22.6 0.3 8.8e-05 21.5 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CDO68836.1 - 0.0012 17.7 0.2 0.028 13.2 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CDO68836.1 - 0.0018 17.2 2.4 0.028 13.3 0.8 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CDO68836.1 - 0.079 11.5 0.8 0.13 10.8 0.6 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 CDO68836.1 - 0.083 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO68836.1 - 0.11 12.5 0.6 0.35 10.9 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Aminotran_1_2 PF00155.16 CDO68837.1 - 4.8e-65 219.8 0.0 5.7e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CDO68837.1 - 1.1e-10 41.1 0.0 2.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CDO68837.1 - 5.5e-06 25.7 0.0 8.2e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CDO68837.1 - 1.6e-05 23.3 0.0 2.9e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CDO68837.1 - 0.00067 18.4 0.0 0.13 11.0 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V OKR_DC_1 PF01276.15 CDO68837.1 - 0.16 10.4 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain GPI-anchored PF10342.4 CDO68838.1 - 2.6e-05 24.6 1.5 2.6e-05 24.6 1.0 2.7 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1353 PF07087.6 CDO68838.1 - 0.024 14.1 0.1 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) DUF566 PF04484.7 CDO68838.1 - 6.9 6.0 9.7 9.7 5.5 6.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Aldo_ket_red PF00248.16 CDO68839.1 - 8.5e-28 96.9 0.0 1.2e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family GPI-anchored PF10342.4 CDO68841.1 - 3e-06 27.6 0.0 4.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RNase_H2_suC PF08615.6 CDO68842.1 - 2.2e-23 82.6 0.0 2.7e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Pkinase PF00069.20 CDO68843.1 - 0.00031 19.9 0.0 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CDO68843.1 - 0.011 15.4 0.2 0.024 14.3 0.2 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_6 PF12697.2 CDO68845.1 - 1.6e-11 44.5 2.7 3.2e-11 43.5 1.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO68845.1 - 8.1e-05 22.4 0.0 0.00015 21.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ytp1 PF10355.4 CDO68846.1 - 7e-74 248.4 9.8 9.5e-74 247.9 6.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) Tic20 PF09685.5 CDO68846.1 - 0.038 13.9 0.1 0.038 13.9 0.1 2.9 2 1 0 2 2 2 0 Tic20-like protein Cytochrom_B561 PF03188.11 CDO68846.1 - 0.64 9.8 14.1 0.048 13.4 1.6 3.4 3 1 0 3 3 3 0 Eukaryotic cytochrome b561 zf-C3HC4_2 PF13923.1 CDO68847.1 - 2.7e-09 36.9 10.1 4.4e-09 36.2 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO68847.1 - 4.2e-09 35.9 6.6 6.9e-09 35.2 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO68847.1 - 1.1e-08 34.6 9.1 1.8e-08 34.0 6.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CDO68847.1 - 4e-08 32.7 10.0 6.5e-08 32.1 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDO68847.1 - 1.3e-07 31.3 11.3 2.1e-07 30.6 7.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CDO68847.1 - 4.2e-07 29.5 8.6 6.5e-07 28.9 5.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.15 CDO68847.1 - 0.0034 16.8 6.8 0.0063 16.0 4.7 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 CDO68847.1 - 0.0037 16.9 6.1 0.0077 15.9 4.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 CDO68847.1 - 0.12 12.0 6.1 0.22 11.1 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HALZ PF02183.13 CDO68847.1 - 0.22 11.2 2.3 12 5.7 0.4 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4592 PF15262.1 CDO68847.1 - 3.8 8.0 10.9 0.22 12.0 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4592) zf-RING_6 PF14835.1 CDO68847.1 - 4.5 7.1 7.9 14 5.5 5.5 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Steroid_dh PF02544.11 CDO68848.1 - 6.8e-25 87.5 5.3 4.7e-15 55.6 4.0 3.2 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CDO68848.1 - 1.7e-06 27.4 2.0 2.7e-05 23.5 1.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Pkinase PF00069.20 CDO68850.1 - 0.0033 16.6 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain AAA_17 PF13207.1 CDO68851.1 - 0.00011 23.0 0.0 0.00025 21.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDO68851.1 - 0.03 14.2 0.0 0.06 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 CDO68851.1 - 0.13 12.5 0.0 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CDO68851.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 CDO68851.1 - 0.2 10.6 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ubiquitin PF00240.18 CDO68852.1 - 6.7e-07 28.6 0.3 2.3e-06 26.8 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CDO68852.1 - 9.3e-06 25.8 0.1 2.8e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 CDO68852.1 - 0.0054 16.3 0.1 0.039 13.6 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.13 CDO68852.1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain DUF4431 PF14485.1 CDO68852.1 - 0.076 12.6 0.0 3.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) Amidohydro_1 PF01979.15 CDO68853.1 - 1.7e-28 100.2 1.1 2.7e-28 99.5 0.7 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CDO68853.1 - 4.4e-10 39.2 0.1 1.2e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CDO68853.1 - 3.2e-09 37.2 0.2 0.00023 21.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 CDO68853.1 - 6.5e-05 22.3 3.3 0.81 8.8 0.0 3.5 1 1 2 3 3 3 3 Amidohydrolase family HSP70 PF00012.15 CDO68854.1 - 7e-267 886.2 15.1 8e-267 886.0 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CDO68854.1 - 2.3e-14 52.7 11.0 1.3e-13 50.2 1.3 3.2 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 CDO68854.1 - 0.002 17.9 11.5 0.81 9.5 0.0 4.8 3 1 1 4 4 4 3 Cell division protein FtsA FGGY_C PF02782.11 CDO68854.1 - 0.0026 17.3 0.1 0.0071 15.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1748 PF08520.5 CDO68854.1 - 0.051 13.2 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) FAM178 PF14816.1 CDO68854.1 - 0.26 9.9 3.0 0.42 9.2 2.1 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 MIF4G PF02854.14 CDO68855.1 - 2.1e-57 193.9 0.1 5e-57 192.6 0.1 1.7 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CDO68855.1 - 4e-19 68.2 0.0 1.4e-18 66.5 0.0 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 CDO68855.1 - 4.2e-11 42.5 0.5 1.4e-10 40.8 0.2 1.9 2 0 0 2 2 2 1 MA3 domain End3 PF12761.2 CDO68856.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Pkinase PF00069.20 CDO68857.1 - 0.031 13.4 0.5 0.086 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain PPV_E1_N PF00524.13 CDO68857.1 - 0.054 13.7 4.7 0.14 12.4 3.3 1.6 1 0 0 1 1 1 0 E1 Protein, N terminal domain SAP PF02037.22 CDO68859.1 - 0.0093 15.4 0.2 0.31 10.6 0.0 2.3 2 0 0 2 2 2 1 SAP domain Nucleic_acid_bd PF13820.1 CDO68859.1 - 0.04 13.5 0.1 0.053 13.1 0.1 1.2 1 0 0 1 1 1 0 Putative nucleic acid-binding region DUF3632 PF12311.3 CDO68860.1 - 2.3e-15 56.8 0.0 1.3e-14 54.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) Cu_bind_like PF02298.12 CDO68861.1 - 0.00064 19.4 0.8 0.75 9.6 0.1 3.4 3 1 0 3 3 3 2 Plastocyanin-like domain Copper-bind PF00127.15 CDO68861.1 - 0.0066 16.6 6.7 3.1 8.0 0.1 3.8 2 2 1 3 3 3 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 CDO68861.1 - 0.021 14.6 0.5 0.39 10.6 0.1 2.6 2 1 0 2 2 2 0 Cupredoxin-like domain MUG113 PF13455.1 CDO68862.1 - 2.2e-14 53.6 0.0 2e-11 44.2 0.0 2.6 2 0 0 2 2 2 2 Meiotically up-regulated gene 113 T5orf172 PF10544.4 CDO68862.1 - 6.4e-09 36.1 0.1 6e-08 33.0 0.0 2.6 2 1 0 2 2 2 1 T5orf172 domain AAA_32 PF13654.1 CDO68862.1 - 0.16 10.5 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain dsDNA_bind PF01984.15 CDO68863.1 - 4e-13 49.2 4.5 1.8e-08 34.3 1.1 2.0 1 1 1 2 2 2 2 Double-stranded DNA-binding domain zf-RING_4 PF14570.1 CDO68864.1 - 1.7e-20 72.3 11.5 2.8e-20 71.6 8.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CDO68864.1 - 5.6e-05 22.7 8.6 9.8e-05 21.9 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 CDO68864.1 - 0.00027 20.5 0.0 0.00077 19.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO68864.1 - 0.003 17.3 0.0 0.0095 15.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 CDO68864.1 - 0.0062 16.5 13.1 0.011 15.7 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 CDO68864.1 - 0.078 12.7 4.3 0.14 11.8 3.0 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.1 CDO68864.1 - 0.23 11.2 2.8 0.58 9.9 1.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Ycf1 PF05758.7 CDO68864.1 - 0.67 7.5 6.5 1.2 6.7 4.5 1.4 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 CDO68864.1 - 6.5 5.2 9.9 5.2 5.5 5.5 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein zf-MYND PF01753.13 CDO68868.1 - 1.5e-11 43.9 6.8 2.4e-11 43.3 4.7 1.4 1 0 0 1 1 1 1 MYND finger Sas10_Utp3 PF04000.10 CDO68869.1 - 6.5e-12 45.4 0.0 1.1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Med2 PF11214.3 CDO68869.1 - 0.042 13.8 0.5 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 2 UCH_1 PF13423.1 CDO68870.1 - 9.8e-44 149.9 0.3 5.8e-23 81.7 0.0 2.2 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CDO68870.1 - 1.6e-25 90.2 0.0 3.3e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 CDO68870.1 - 3.9e-07 29.4 0.0 6.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 CDO68870.1 - 0.003 17.3 1.9 11 6.1 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Arginase PF00491.16 CDO68871.1 - 3.9e-72 242.8 0.1 1.9e-44 152.0 0.0 2.1 2 0 0 2 2 2 2 Arginase family DUF3535 PF12054.3 CDO68873.1 - 1.6e-91 307.1 0.2 5.4e-91 305.4 0.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 CDO68873.1 - 7.9e-76 254.7 0.0 1.1e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDO68873.1 - 1.3e-12 47.3 0.0 2.8e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 CDO68873.1 - 8.7e-12 44.0 14.8 0.064 13.3 0.0 9.0 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 CDO68873.1 - 0.00043 20.6 12.7 62 4.2 0.1 8.7 9 1 1 10 10 10 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CDO68873.1 - 0.0052 17.1 0.0 1.3 9.4 0.0 2.9 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region DUF1546 PF07571.8 CDO68873.1 - 0.024 14.7 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Cupin_8 PF13621.1 CDO68874.1 - 2.9e-36 125.2 0.0 5.2e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CDO68874.1 - 3.9e-06 26.3 0.0 6.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.6 CDO68874.1 - 5.2e-05 22.6 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.17 CDO68874.1 - 0.014 15.5 0.1 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase AraC_binding PF02311.14 CDO68874.1 - 0.023 14.4 0.2 0.048 13.3 0.2 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain FAD_binding_2 PF00890.19 CDO68875.1 - 3.9e-103 345.4 7.4 2.1e-94 316.7 1.0 2.1 1 1 1 2 2 2 2 FAD binding domain Succ_DH_flav_C PF02910.15 CDO68875.1 - 2.2e-48 163.3 1.1 3.2e-48 162.8 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 CDO68875.1 - 2.7e-06 26.6 0.0 0.0063 15.6 0.0 3.1 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 CDO68875.1 - 5.1e-06 25.5 1.1 0.0069 15.2 1.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 CDO68875.1 - 3.1e-05 23.0 0.3 0.00097 18.1 0.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CDO68875.1 - 4.7e-05 23.3 3.3 0.0019 18.1 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CDO68875.1 - 0.0032 16.5 0.1 0.0056 15.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Transaldolase PF00923.14 CDO68875.1 - 0.026 13.6 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Transaldolase Pyr_redox_3 PF13738.1 CDO68875.1 - 0.06 13.3 0.2 0.9 9.5 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO68875.1 - 0.089 11.2 2.3 0.29 9.5 0.6 2.5 3 1 1 4 4 4 0 HI0933-like protein RabGAP-TBC PF00566.13 CDO68876.1 - 1.9e-29 102.7 0.0 3.5e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain COG2 PF06148.6 CDO68876.1 - 0.26 11.1 0.8 0.46 10.3 0.6 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cullin_binding PF03556.10 CDO68877.1 - 5.8e-28 97.3 0.3 7.1e-28 97.1 0.2 1.1 1 0 0 1 1 1 1 Cullin binding Dimer_Tnp_hAT PF05699.9 CDO68878.1 - 2.6e-10 39.7 0.0 5.7e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.10 CDO68878.1 - 3e-06 26.7 0.0 5.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF2603 PF10788.4 CDO68878.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) DUF59 PF01883.14 CDO68879.1 - 1.3e-06 28.2 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF59 Dynamin_M PF01031.15 CDO68881.1 - 2e-105 351.8 0.0 3.3e-105 351.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CDO68881.1 - 7e-55 185.3 0.0 1.4e-54 184.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CDO68881.1 - 2.2e-27 94.7 5.6 2.2e-27 94.7 3.9 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CDO68881.1 - 0.00051 19.9 0.8 0.0053 16.6 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CDO68881.1 - 0.085 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein GHL13 PF14883.1 CDO68883.1 - 0.017 14.3 0.1 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 DUF4464 PF14713.1 CDO68883.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) Med1 PF10744.4 CDO68884.1 - 0.0059 15.4 0.1 3.3 6.3 0.0 3.1 2 1 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Glyco_hydro_88 PF07470.8 CDO68886.1 - 5.4e-13 48.6 0.5 5.9e-13 48.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 tRNA-synt_1b PF00579.20 CDO68887.1 - 3.6e-18 65.6 0.0 7.9e-18 64.5 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TBP PF00352.16 CDO68888.1 - 1.7e-68 225.9 0.2 3.7e-34 115.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CDO68888.1 - 0.0063 16.5 8.0 1 9.4 0.0 3.8 3 1 0 3 3 3 2 Domain of unknown function (DUF3378) DUF605 PF04652.11 CDO68888.1 - 0.086 12.2 14.1 0.095 12.0 9.8 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 CDO68888.1 - 7.6 6.3 11.8 12 5.7 8.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.4 CDO68888.1 - 9 4.8 10.4 12 4.4 7.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.7 CDO68888.1 - 9.8 4.7 10.8 13 4.2 7.5 1.1 1 0 0 1 1 1 0 Hamartin protein SLT_L PF14718.1 CDO68889.1 - 0.13 12.0 0.1 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain NTF2 PF02136.15 CDO68890.1 - 7.4e-29 100.5 0.0 1.4e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Lysine_decarbox PF03641.9 CDO68890.1 - 4.7e-23 81.4 0.0 8.4e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase SSI PF00720.12 CDO68890.1 - 0.042 13.7 0.2 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Subtilisin inhibitor-like PI-PLC-X PF00388.14 CDO68891.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Sterol-sensing PF12349.3 CDO68892.1 - 6.3e-35 119.8 10.0 2.4e-34 118.0 6.2 2.4 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CDO68892.1 - 3.3e-16 58.4 2.6 4.9e-16 57.8 1.8 1.1 1 0 0 1 1 1 1 Patched family Biotin_lipoyl PF00364.17 CDO68893.1 - 2.3e-19 68.8 0.2 4.7e-19 67.8 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CDO68893.1 - 1.8e-07 30.6 0.0 4.4e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain DUF2360 PF10152.4 CDO68893.1 - 0.017 15.4 4.5 0.017 15.4 3.1 2.4 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Biotin_lipoyl_2 PF13533.1 CDO68893.1 - 0.05 13.2 0.1 0.22 11.2 0.0 2.1 1 1 1 2 2 2 0 Biotin-lipoyl like Rad1 PF02144.11 CDO68894.1 - 2.4e-73 246.3 0.0 2.7e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF177 PF02620.12 CDO68894.1 - 0.05 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1399 Hat1_N PF10394.4 CDO68895.1 - 7.4e-44 149.6 0.5 1.3e-43 148.8 0.3 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 CDO68895.1 - 0.0038 17.3 0.0 0.008 16.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box-like PF12937.2 CDO68896.1 - 1.8e-05 24.3 0.6 7.9e-05 22.2 0.1 2.3 2 0 0 2 2 2 1 F-box-like Acetyltransf_7 PF13508.1 CDO68898.1 - 0.00047 20.2 0.0 0.54 10.4 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDO68898.1 - 0.011 15.8 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO68898.1 - 0.036 14.0 0.0 1.6 8.8 0.0 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family MIF PF01187.13 CDO68899.1 - 6.8e-18 64.8 0.0 7.4e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Amidohydro_1 PF01979.15 CDO68900.1 - 6.1e-15 55.6 0.2 4.9e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 CDO68900.1 - 2.8e-11 43.9 0.4 0.00011 22.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 CDO68900.1 - 3.1e-11 42.9 0.3 9.9e-11 41.3 0.2 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CDO68900.1 - 3e-05 23.4 1.7 0.031 13.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family zf-MYND PF01753.13 CDO68901.1 - 1.3e-09 37.8 15.0 3e-09 36.6 10.4 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 CDO68901.1 - 0.0027 17.5 7.7 0.0062 16.3 5.3 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.1 CDO68901.1 - 0.02 14.0 0.5 0.043 13.0 0.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Pyr_redox_2 PF07992.9 CDO68905.1 - 9e-34 117.1 2.3 2.6e-33 115.6 1.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CDO68905.1 - 3.8e-29 100.9 0.4 7.7e-28 96.7 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain FAD_oxidored PF12831.2 CDO68905.1 - 3.4e-08 32.9 0.2 4.7e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CDO68905.1 - 6.7e-06 24.8 4.8 0.011 14.1 1.1 2.8 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 CDO68905.1 - 0.0016 17.3 4.2 0.0036 16.2 2.9 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 CDO68905.1 - 0.0096 15.0 0.4 0.018 14.1 0.3 1.4 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 CDO68905.1 - 0.024 13.5 0.0 0.14 11.0 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CDO68905.1 - 0.027 14.4 1.7 0.07 13.1 1.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CDO68905.1 - 0.055 13.8 4.0 3.4 8.1 1.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CDO68905.1 - 0.2 10.5 4.8 0.26 10.1 1.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CDO68905.1 - 0.3 10.8 5.2 2.8 7.7 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 CDO68905.1 - 4.9 5.8 11.0 0.34 9.7 3.4 2.1 3 0 0 3 3 3 0 FAD binding domain DUF72 PF01904.13 CDO68908.1 - 0.039 13.7 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF72 Rpp20 PF12328.3 CDO68909.1 - 3.2e-07 30.1 0.0 3.2e-06 26.8 0.0 2.2 2 1 1 3 3 3 1 Rpp20 subunit of nuclear RNase MRP and P Prok-E2_B PF14461.1 CDO68909.1 - 0.056 13.1 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B Alba PF01918.16 CDO68909.1 - 0.1 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Alba eRF1_2 PF03464.10 CDO68910.1 - 2.2e-46 157.4 0.1 4e-46 156.6 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CDO68910.1 - 1.7e-39 134.6 0.3 3.3e-39 133.6 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CDO68910.1 - 2.2e-26 91.9 0.0 4.2e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Ribonuclease_3 PF00636.21 CDO68911.1 - 3.1e-38 130.7 0.0 2.5e-18 66.6 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CDO68911.1 - 1.3e-24 86.5 0.1 2.6e-14 53.3 0.0 3.5 2 2 0 2 2 2 2 Ribonuclease-III-like DEAD PF00270.24 CDO68911.1 - 1.2e-14 54.1 0.0 2.2e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDO68911.1 - 1.3e-14 54.5 0.0 2.3e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.9 CDO68911.1 - 3e-11 42.9 0.0 7.1e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 CDO68911.1 - 4.3e-06 26.4 0.2 1.3e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CDO68911.1 - 4e-05 22.5 0.0 8e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Phosducin PF02114.11 CDO68912.1 - 4.2e-08 32.2 0.0 7.6e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Phosducin PNPOx_C PF10590.4 CDO68912.1 - 0.23 10.9 2.1 0.55 9.7 1.4 1.6 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region PLRV_ORF5 PF01690.12 CDO68912.1 - 1.7 7.6 6.5 0.96 8.5 1.9 2.0 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Ras PF00071.17 CDO68913.1 - 6.2e-49 165.5 0.2 7.8e-49 165.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO68913.1 - 1.1e-11 45.2 0.0 1.9e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO68913.1 - 8.2e-08 31.6 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CDO68913.1 - 0.00021 20.8 0.1 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF718 PF05336.8 CDO68914.1 - 3.9e-29 100.5 0.1 4.4e-29 100.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Ras PF00071.17 CDO68915.1 - 9e-37 125.9 0.0 1.1e-36 125.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO68915.1 - 6.7e-08 33.0 0.0 9.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein DUF1077 PF06417.7 CDO68916.1 - 1.2e-45 153.9 0.0 1.4e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TrwC PF08751.6 CDO68916.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 TrwC relaxase MIF4G PF02854.14 CDO68917.1 - 6e-29 100.9 0.7 4.9e-28 97.9 0.0 2.4 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CDO68917.1 - 8.8e-26 89.8 0.3 1.6e-25 89.0 0.2 1.4 1 0 0 1 1 1 1 MA3 domain Senescence PF06911.7 CDO68917.1 - 2.2e-21 76.3 1.2 3.2e-13 49.7 0.0 2.5 2 0 0 2 2 2 2 Senescence-associated protein Mem_trans PF03547.13 CDO68917.1 - 0.16 10.2 0.3 0.32 9.2 0.2 1.4 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.9 CDO68917.1 - 8.5 4.2 31.4 0.0076 14.3 6.5 2.8 3 0 0 3 3 3 0 CDC45-like protein VCBS PF13517.1 CDO68919.1 - 1e-20 73.8 16.9 4.5e-09 36.5 0.4 5.1 2 2 3 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CDO68919.1 - 6.9e-18 63.7 5.4 0.0019 17.8 0.3 6.4 6 0 0 6 6 6 4 FG-GAP repeat TcdB_toxin_midN PF12256.3 CDO68919.1 - 1.3e-07 31.2 5.8 0.27 10.6 0.0 5.6 3 1 3 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region CRF-BP PF05428.6 CDO68922.1 - 0.064 12.0 0.0 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) Cellulase PF00150.13 CDO68923.1 - 1.5e-12 47.3 0.3 1.9e-12 46.9 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.17 CDO68925.1 - 1.7e-36 123.7 0.0 7.7e-20 70.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO68925.1 - 6.1e-17 61.3 0.0 3.8e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO68925.1 - 7.6e-12 44.9 0.0 1.3e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CDO68925.1 - 0.0073 15.7 0.2 0.21 11.1 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 CDO68925.1 - 0.12 12.1 0.0 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 Peptidase_M50B PF13398.1 CDO68927.1 - 5e-35 120.7 17.6 5.6e-35 120.5 11.4 1.6 1 1 0 1 1 1 1 Peptidase M50B-like ABC_tran PF00005.22 CDO68928.1 - 1.9e-43 148.0 0.1 1.2e-20 74.2 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CDO68928.1 - 2.9e-16 60.2 0.2 0.014 15.4 0.0 4.4 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 CDO68928.1 - 7.4e-14 51.5 0.8 0.00059 19.1 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CDO68928.1 - 1.8e-08 33.7 0.2 0.0073 15.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CDO68928.1 - 1.8e-07 32.0 0.1 0.0021 18.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CDO68928.1 - 1.9e-06 28.0 0.0 0.051 13.7 0.0 3.7 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 CDO68928.1 - 2.7e-06 27.1 0.0 0.016 15.1 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CDO68928.1 - 4.5e-06 26.6 0.1 0.0033 17.2 0.0 3.3 3 1 1 4 4 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 CDO68928.1 - 8.6e-06 26.0 1.4 0.0069 16.6 0.0 3.6 4 0 0 4 4 2 1 AAA domain HEAT_2 PF13646.1 CDO68928.1 - 9.2e-06 25.8 18.6 0.0074 16.5 2.0 4.6 3 1 2 5 5 4 3 HEAT repeats AAA_10 PF12846.2 CDO68928.1 - 1e-05 25.1 0.1 0.047 13.1 0.1 3.5 4 0 0 4 4 4 2 AAA-like domain Miro PF08477.8 CDO68928.1 - 3.3e-05 24.3 0.0 0.2 12.1 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 CDO68928.1 - 3.5e-05 23.7 0.0 0.11 12.3 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 CDO68928.1 - 5.5e-05 23.5 4.8 0.073 13.3 0.0 3.4 4 0 0 4 4 4 2 AAA domain Chromo PF00385.19 CDO68928.1 - 7e-05 22.4 0.2 0.00015 21.3 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.7 CDO68928.1 - 7.8e-05 22.3 0.1 0.23 11.1 0.0 2.9 2 0 0 2 2 2 2 NACHT domain HEAT PF02985.17 CDO68928.1 - 9.4e-05 22.1 8.6 0.13 12.3 0.0 5.4 6 0 0 6 6 4 1 HEAT repeat MobB PF03205.9 CDO68928.1 - 0.0001 22.0 0.1 0.23 11.1 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CDO68928.1 - 0.00012 21.3 0.0 0.15 11.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CDO68928.1 - 0.00013 22.1 0.0 0.3 11.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 CDO68928.1 - 0.00015 21.9 0.0 2.6 8.2 0.0 4.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CDO68928.1 - 0.00025 20.9 0.0 0.43 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CDO68928.1 - 0.00025 20.8 0.1 2.8 7.5 0.0 3.7 3 0 0 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 CDO68928.1 - 0.00026 20.4 0.0 1.7 8.0 0.0 3.9 4 0 0 4 4 4 1 AAA domain ArgK PF03308.11 CDO68928.1 - 0.00061 18.6 0.1 0.38 9.4 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_28 PF13521.1 CDO68928.1 - 0.00063 19.7 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CDO68928.1 - 0.00079 18.9 0.1 0.55 9.6 0.0 3.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_15 PF13175.1 CDO68928.1 - 0.0017 17.4 0.6 2.6 7.0 0.0 3.7 3 1 1 4 4 4 1 AAA ATPase domain AAA_13 PF13166.1 CDO68928.1 - 0.0045 15.5 0.9 1.3 7.4 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CDO68928.1 - 0.0072 16.3 13.1 0.012 15.5 0.2 4.6 3 2 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 CDO68928.1 - 0.013 15.3 0.0 2.6 7.9 0.0 3.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CDO68928.1 - 0.016 14.1 0.1 3.2 6.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) U3snoRNP10 PF12397.3 CDO68928.1 - 0.019 14.9 0.6 0.058 13.3 0.4 1.8 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 Dynamin_N PF00350.18 CDO68928.1 - 0.028 14.2 0.0 1.2 8.9 0.0 2.9 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.10 CDO68928.1 - 0.043 13.5 0.1 5.8 6.6 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 CDO68928.1 - 0.044 13.5 0.7 1.5 8.6 0.0 3.4 3 0 0 3 3 2 0 Part of AAA domain KAP_NTPase PF07693.9 CDO68928.1 - 0.056 12.4 0.4 0.39 9.6 0.0 2.4 3 0 0 3 3 3 0 KAP family P-loop domain HEAT_EZ PF13513.1 CDO68928.1 - 0.079 13.4 12.5 4.9 7.7 2.6 5.3 3 2 2 5 5 5 0 HEAT-like repeat ATP-synt_ab PF00006.20 CDO68928.1 - 0.085 12.3 0.1 3.4 7.1 0.0 3.4 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 CDO68928.1 - 0.16 11.7 5.1 14 5.4 0.1 4.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) V_ATPase_I PF01496.14 CDO68929.1 - 1.3e-280 932.6 0.0 1.5e-280 932.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Clusterin PF01093.12 CDO68929.1 - 0.0036 16.1 0.1 0.0058 15.4 0.1 1.2 1 0 0 1 1 1 1 Clusterin SlyX PF04102.7 CDO68929.1 - 0.0055 17.0 3.0 0.016 15.5 1.0 2.5 3 0 0 3 3 3 1 SlyX Rab5-bind PF09311.6 CDO68930.1 - 0.029 14.2 1.1 0.045 13.6 0.8 1.4 1 1 0 1 1 1 0 Rabaptin-like protein DUF1870 PF08965.5 CDO68930.1 - 0.066 12.8 0.0 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) SseC PF04888.7 CDO68930.1 - 0.075 12.3 0.0 0.075 12.3 0.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Melibiase PF02065.13 CDO68933.1 - 0.1 11.3 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Melibiase DDE_Tnp_4 PF13359.1 CDO68934.1 - 1.1e-10 41.2 0.0 1.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SPT6_acidic PF14632.1 CDO68934.1 - 0.0066 16.5 1.6 0.011 15.9 1.1 1.2 1 0 0 1 1 1 1 Acidic N-terminal SPT6 DDE_1 PF03184.14 CDO68935.1 - 1.6e-30 105.8 0.0 2.2e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-B_dimeris PF09026.5 CDO68935.1 - 0.028 14.6 1.7 0.06 13.5 1.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HTH_Tnp_Tc5 PF03221.11 CDO68936.1 - 1.9e-10 40.3 0.1 6.8e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 CDO68936.1 - 1.1e-08 34.4 0.0 2.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Utp12 PF04003.7 CDO68936.1 - 0.046 13.6 0.2 0.16 11.9 0.1 1.9 1 1 0 1 1 1 0 Dip2/Utp12 Family DUF2407_C PF13373.1 CDO68936.1 - 0.16 11.8 4.6 0.14 12.0 0.6 2.5 2 1 1 3 3 3 0 DUF2407 C-terminal domain JmjC PF02373.17 CDO68938.1 - 1.6e-38 131.4 0.0 3.2e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 CDO68938.1 - 1.4e-15 56.4 0.4 3.5e-15 55.2 0.3 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 CDO68938.1 - 5.1e-13 48.9 1.5 7.1e-13 48.5 0.3 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CDO68938.1 - 2.6e-12 46.7 0.5 7.7e-12 45.1 0.4 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.24 CDO68938.1 - 0.0067 16.0 2.1 0.02 14.5 1.5 1.8 1 0 0 1 1 1 1 PHD-finger CAP59_mtransfer PF11735.3 CDO68940.1 - 1.9e-45 154.9 0.0 3.2e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Nup84_Nup100 PF04121.8 CDO68941.1 - 2e-84 283.6 0.0 1.5e-83 280.7 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Nic96 PF04097.9 CDO68941.1 - 0.06 11.4 0.1 0.2 9.7 0.1 1.8 1 1 0 1 1 1 0 Nup93/Nic96 tRNA-synt_1 PF00133.17 CDO68942.1 - 1.6e-205 683.6 0.0 1.2e-204 680.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CDO68942.1 - 6.5e-32 110.4 0.2 1.4e-31 109.2 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CDO68942.1 - 2.4e-17 62.6 0.0 9.5e-10 37.6 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CDO68942.1 - 4.9e-12 45.5 0.1 1.3e-07 31.1 0.1 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 CDO68942.1 - 0.009 15.1 0.0 0.24 10.4 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.4 CDO68942.1 - 0.023 14.7 0.7 0.023 14.7 0.5 3.8 4 0 0 4 4 4 0 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 CDO68942.1 - 0.043 12.6 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 CDO68942.1 - 0.058 12.5 0.1 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) RVT_2 PF07727.9 CDO68943.1 - 6.2e-24 84.3 0.0 1.7e-19 69.8 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO68944.1 - 2.8e-29 101.6 0.0 4.9e-27 94.4 0.0 2.9 2 0 0 2 2 2 1 Integrase core domain DDE_1 PF03184.14 CDO68944.1 - 1.4e-27 96.2 0.0 2.2e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease UBN2_2 PF14227.1 CDO68944.1 - 1.1e-14 54.0 0.0 2.5e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO68944.1 - 4.8e-11 42.4 0.0 7.7e-10 38.6 0.0 2.6 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO68944.1 - 3.6e-09 36.1 0.7 1.2e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain DDE_3 PF13358.1 CDO68944.1 - 7.4e-07 29.0 0.1 2.6e-06 27.2 0.1 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease rve_3 PF13683.1 CDO68944.1 - 3e-05 23.4 1.1 9e-05 21.9 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain BRO1 PF03097.13 CDO68946.1 - 1.9e-82 277.0 0.0 3.2e-82 276.2 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CDO68946.1 - 7.8e-48 162.9 13.5 1.4e-46 158.8 9.4 2.7 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV Syntaxin_2 PF14523.1 CDO68946.1 - 0.41 10.7 2.5 5.4 7.0 0.4 3.3 3 1 0 3 3 3 0 Syntaxin-like protein DUF3421 PF11901.3 CDO68947.1 - 1.1e-17 63.8 0.0 1.7e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) SR-25 PF10500.4 CDO68947.1 - 2.2 7.6 18.6 3 7.2 12.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WLM PF08325.5 CDO68948.1 - 2.6e-23 82.8 14.2 6.2e-17 62.0 5.2 3.8 2 1 1 3 3 3 2 WLM domain DUF45 PF01863.12 CDO68948.1 - 0.00031 20.6 0.2 0.00069 19.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 PFK PF00365.15 CDO68949.1 - 1.2e-128 427.9 0.3 3.1e-81 272.4 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase DUF4646 PF15496.1 CDO68949.1 - 0.061 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) PapJ PF14855.1 CDO68949.1 - 0.077 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone KilA-N PF04383.8 CDO68950.1 - 0.03 13.9 1.2 0.39 10.3 0.0 2.4 2 1 0 2 2 2 0 KilA-N domain DUF4316 PF14195.1 CDO68950.1 - 0.15 12.1 2.9 0.5 10.4 2.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Casc1 PF12366.3 CDO68950.1 - 0.27 10.7 7.5 0.39 10.1 5.2 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 TMF_DNA_bd PF12329.3 CDO68952.1 - 0.00033 20.3 9.1 0.00033 20.3 6.3 5.4 4 1 2 6 6 6 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CDO68952.1 - 0.0036 16.9 33.1 0.0036 16.9 23.0 3.4 2 1 1 3 3 3 1 IncA protein Reo_sigmaC PF04582.7 CDO68952.1 - 0.017 14.3 7.0 0.021 14.0 4.1 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein FliD_N PF02465.13 CDO68952.1 - 0.03 14.6 13.1 2.9 8.3 5.2 3.4 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Baculo_PEP_C PF04513.7 CDO68952.1 - 2.3 8.0 14.7 1 9.1 0.7 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.9 CDO68952.1 - 8.5 5.9 35.4 0.11 12.0 8.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Proteasome PF00227.21 CDO68953.1 - 8.2e-54 181.7 0.1 1.4e-53 180.9 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDO68953.1 - 2.2e-14 52.4 0.2 4.3e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CHZ PF09649.5 CDO68954.1 - 7.1e-08 31.5 0.4 7.1e-08 31.5 0.2 3.1 1 1 1 2 2 1 1 Histone chaperone domain CHZ Prothymosin PF03247.9 CDO68954.1 - 0.0071 16.4 20.8 0.0071 16.4 14.4 2.1 2 0 0 2 2 2 1 Prothymosin/parathymosin family Utp14 PF04615.8 CDO68954.1 - 0.046 11.8 8.7 0.048 11.8 6.0 1.0 1 0 0 1 1 1 0 Utp14 protein MYCBPAP PF14646.1 CDO68954.1 - 0.14 10.8 1.8 0.14 10.8 1.3 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family DUF740 PF05340.7 CDO68954.1 - 0.32 9.3 5.4 0.36 9.1 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) FAM176 PF14851.1 CDO68954.1 - 0.49 10.0 12.5 0.057 13.1 5.6 1.6 1 1 1 2 2 2 0 FAM176 family PI3K_1B_p101 PF10486.4 CDO68954.1 - 0.77 7.2 5.9 0.78 7.2 4.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF506 PF04720.7 CDO68954.1 - 1.3 8.6 3.7 1.6 8.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) FYDLN_acid PF09538.5 CDO68954.1 - 1.5 9.4 21.9 0.46 11.0 9.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Sporozoite_P67 PF05642.6 CDO68954.1 - 1.7 6.4 6.0 1.6 6.5 4.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Retinal PF15449.1 CDO68954.1 - 2.7 5.5 6.3 3.3 5.2 4.4 1.1 1 0 0 1 1 1 0 Retinal protein TEX19 PF15553.1 CDO68954.1 - 3.9 7.3 8.2 4.9 6.9 5.7 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 eIF-3c_N PF05470.7 CDO68954.1 - 4.2 5.3 8.9 4.4 5.2 6.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2146 PF10220.4 CDO68954.1 - 5.3 4.8 9.1 5.9 4.7 6.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Radial_spoke PF04712.7 CDO68954.1 - 5.9 5.5 11.4 1 8.0 5.4 1.4 2 0 0 2 2 2 0 Radial spokehead-like protein RRN3 PF05327.6 CDO68954.1 - 8.1 4.4 11.4 9 4.2 7.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA_18 PF13238.1 CDO68956.1 - 3.3e-10 40.3 0.0 2.8e-09 37.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDO68956.1 - 6.3e-09 36.6 0.0 1.1e-08 35.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDO68956.1 - 2.9e-08 33.7 0.0 0.00034 20.5 0.0 3.0 2 1 1 3 3 3 2 AAA domain SKI PF01202.17 CDO68956.1 - 5.2e-06 26.4 0.0 2.6e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Shikimate kinase AAA_19 PF13245.1 CDO68956.1 - 0.00034 20.2 0.0 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 CDO68956.1 - 0.00046 20.2 0.0 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 CDO68956.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 CDO68956.1 - 0.0021 17.6 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CDO68956.1 - 0.0029 17.7 0.0 0.0054 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CDO68956.1 - 0.0043 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CDO68956.1 - 0.0059 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase Cytidylate_kin2 PF13189.1 CDO68956.1 - 0.01 15.7 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_5 PF07728.9 CDO68956.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 CDO68956.1 - 0.015 14.2 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 CDO68956.1 - 0.041 13.4 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PEPCK_ATP PF01293.15 CDO68956.1 - 0.052 12.0 0.0 0.066 11.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Thymidylate_kin PF02223.12 CDO68956.1 - 0.057 12.7 0.0 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA PF00004.24 CDO68956.1 - 0.058 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CDO68956.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 CDO68956.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.10 CDO68957.1 - 1.6e-10 40.6 10.9 1.6e-10 40.6 7.5 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 CDO68957.1 - 1.8e-10 40.5 6.7 1.8e-10 40.5 4.6 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 CDO68957.1 - 0.37 11.1 14.6 0.14 12.5 7.4 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor WD40_alt PF14077.1 CDO68957.1 - 0.9 9.2 4.3 0.47 10.1 0.5 2.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif UPF0104 PF03706.8 CDO68960.1 - 0.00035 19.9 0.8 0.00053 19.3 0.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) BRO1 PF03097.13 CDO68961.1 - 1.6e-14 53.4 0.0 2.1e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain DUF663 PF04950.7 CDO68962.1 - 3.7e-100 334.7 0.0 5.2e-100 334.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CDO68962.1 - 8.8e-21 73.2 0.0 1.9e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain 5-FTHF_cyc-lig PF01812.15 CDO68962.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family EF-hand_8 PF13833.1 CDO68962.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair SGT1 PF07093.6 CDO68962.1 - 0.84 7.9 9.0 1.2 7.3 6.3 1.2 1 0 0 1 1 1 0 SGT1 protein Vps53_N PF04100.7 CDO68963.1 - 4e-91 305.6 0.2 6.7e-91 304.9 0.2 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 CDO68963.1 - 6.2e-07 28.6 4.3 1.5e-06 27.3 3.0 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF948 PF06103.6 CDO68963.1 - 0.018 14.8 7.0 0.22 11.3 0.0 4.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Sec5 PF15469.1 CDO68963.1 - 0.027 14.1 5.8 0.027 14.1 2.5 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF1664 PF07889.7 CDO68963.1 - 0.95 9.2 11.2 0.18 11.6 2.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) IncA PF04156.9 CDO68963.1 - 3.6 7.1 13.1 4.3 6.8 7.6 2.3 1 1 1 2 2 2 0 IncA protein Autophagy_N PF03986.8 CDO68964.1 - 6.2e-46 155.7 0.4 1.5e-45 154.5 0.0 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CDO68964.1 - 3e-26 91.3 0.2 7.3e-26 90.1 0.1 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CDO68964.1 - 9.4e-12 43.8 1.8 2e-11 42.7 1.3 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-LYAR PF08790.6 CDO68965.1 - 2.9e-12 46.0 2.2 6.4e-12 44.9 1.5 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger SynMuv_product PF06047.6 CDO68966.1 - 4.9e-43 145.1 4.3 4.9e-43 145.1 3.0 3.3 3 0 0 3 3 3 1 Ras-induced vulval development antagonist MIP-T3 PF10243.4 CDO68966.1 - 0.29 9.5 84.2 0.0085 14.6 34.0 2.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 OsmC PF02566.14 CDO68967.1 - 3.3e-14 52.8 0.0 5.2e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Retrotrans_gag PF03732.12 CDO68969.1 - 1.4e-09 37.8 0.3 2.3e-09 37.1 0.2 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein PSD4 PF07631.6 CDO68970.1 - 0.056 13.8 0.1 0.11 12.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) Ndc1_Nup PF09531.5 CDO68971.1 - 6.1e-43 147.1 6.9 8.2e-43 146.7 4.8 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Redoxin PF08534.5 CDO68973.1 - 8e-35 119.5 0.0 9.1e-35 119.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CDO68973.1 - 1.9e-09 37.2 0.0 2.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CDO68974.1 - 2.1e-37 127.9 0.0 2.7e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CDO68974.1 - 1.8e-13 50.2 0.0 2.5e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Pex19 PF04614.7 CDO68975.1 - 2.2e-60 204.3 2.8 2.2e-60 204.3 1.9 1.7 1 1 1 2 2 2 1 Pex19 protein family Solute_trans_a PF03619.11 CDO68976.1 - 6.5e-101 337.2 6.7 7.8e-101 336.9 4.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha APH PF01636.18 CDO68977.1 - 2.2e-09 37.3 0.5 3.3e-09 36.8 0.3 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Med8 PF10232.4 CDO68978.1 - 0.0038 16.7 1.2 0.0045 16.5 0.2 1.6 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription complex subunit 8 HMG_box_2 PF09011.5 CDO68979.1 - 5.1e-14 52.3 7.6 3.8e-11 43.1 0.2 4.1 3 2 0 3 3 3 2 HMG-box domain HMG_box PF00505.14 CDO68979.1 - 6.1e-14 52.0 13.6 1.3e-10 41.3 0.2 4.2 3 2 0 3 3 3 2 HMG (high mobility group) box ApoO PF09769.4 CDO68979.1 - 0.22 11.2 4.9 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein O Med3 PF11593.3 CDO68979.1 - 0.82 8.8 13.4 1 8.5 9.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAF-1_p150 PF11600.3 CDO68979.1 - 8.4 5.6 39.8 0.05 12.9 14.2 2.4 2 1 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF913 PF06025.7 CDO68979.1 - 9.7 4.8 7.1 15 4.1 4.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RGS PF00615.14 CDO68980.1 - 8.2e-10 38.8 1.4 0.0001 22.3 0.1 2.9 2 1 0 2 2 2 2 Regulator of G protein signaling domain L51_S25_CI-B8 PF05047.11 CDO68981.1 - 1.7e-15 56.4 0.0 2.3e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain adh_short PF00106.20 CDO68982.1 - 6.7e-21 74.9 0.3 8.7e-21 74.5 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO68982.1 - 3.6e-09 36.7 0.0 4.5e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO68982.1 - 1.3e-07 31.4 0.1 1.7e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO68982.1 - 3.6e-07 29.8 0.0 4.4e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO68982.1 - 0.00025 21.1 0.3 0.0004 20.4 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding EPSP_synthase PF00275.15 CDO68983.1 - 3.6e-120 401.2 0.0 5.7e-120 400.5 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CDO68983.1 - 9.5e-101 336.1 0.0 4e-100 334.0 0.0 2.0 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CDO68983.1 - 4e-63 213.0 0.0 6.4e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 CDO68983.1 - 2.1e-34 118.6 0.0 2.8e-33 115.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 CDO68983.1 - 1.3e-26 92.4 0.0 4.1e-26 90.8 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CDO68983.1 - 2.5e-12 47.0 0.0 6.8e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CDO68983.1 - 1.3e-10 41.0 0.0 9.5e-10 38.1 0.0 2.3 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 CDO68983.1 - 8.9e-05 23.2 0.1 0.00051 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CDO68983.1 - 0.011 15.6 0.0 0.044 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CDO68983.1 - 0.11 12.5 0.1 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CDO68983.1 - 0.12 12.5 0.0 0.45 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 CDO68983.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase zf-C2H2 PF00096.21 CDO68985.1 - 4.5e-08 32.9 17.1 1.5e-05 25.0 0.8 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO68985.1 - 2.9e-06 27.2 18.3 0.00066 19.8 0.1 4.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CDO68985.1 - 3.7e-05 23.7 14.7 0.0015 18.7 0.5 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger GAGA PF09237.6 CDO68985.1 - 0.081 12.5 9.4 1.1 8.9 0.1 4.1 3 1 1 4 4 4 0 GAGA factor zf-Di19 PF05605.7 CDO68985.1 - 0.14 12.3 4.2 0.099 12.7 0.8 2.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CDO68985.1 - 0.51 10.5 3.3 0.96 9.6 0.0 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CDO68985.1 - 3.9 7.5 8.8 6.4 6.8 0.0 3.4 3 1 0 3 3 3 0 C2H2-type zinc finger Got1 PF04178.7 CDO68986.1 - 4.3e-18 65.5 6.7 4.6e-18 65.4 4.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Pkinase PF00069.20 CDO68987.1 - 2.6e-52 177.5 0.0 3.3e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO68987.1 - 5.5e-38 130.5 0.0 7.4e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO68987.1 - 3.8e-08 32.6 0.0 5.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO68987.1 - 0.018 14.7 0.3 0.18 11.4 0.0 2.5 2 2 0 2 2 2 0 Phosphotransferase enzyme family BAG PF02179.11 CDO68988.1 - 1.2e-14 54.2 0.0 4e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.18 CDO68988.1 - 6.3e-09 35.1 0.0 1.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBN2_2 PF14227.1 CDO68990.1 - 1.7e-14 53.4 0.0 2.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO68990.1 - 2.8e-11 43.2 0.0 3.9e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVT_1 PF00078.22 CDO68991.1 - 1.1e-10 41.2 0.0 2.2e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO68991.1 - 0.092 11.7 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CDO68992.1 - 8.2e-06 25.8 1.6 2e-05 24.5 0.1 2.4 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 CDO68992.1 - 7.3e-05 23.1 0.0 0.0002 21.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO68992.1 - 0.00021 21.0 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CDO68992.1 - 0.0077 16.1 0.1 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 CDO68992.1 - 0.033 14.1 0.2 0.064 13.2 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Peptidase_A2B PF12384.3 CDO68992.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Ty3 transposon peptidase UBN2_2 PF14227.1 CDO68992.1 - 0.13 11.8 0.1 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Macoilin PF09726.4 CDO68992.1 - 0.2 9.9 5.9 0.28 9.4 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein TMEM247 PF15444.1 CDO68993.1 - 3.2 7.5 6.9 5.4 6.7 4.8 1.4 1 1 0 1 1 1 0 Transmembrane protein 247 CBF PF03914.12 CDO68995.1 - 7e-40 136.1 1.1 1.7e-39 134.9 0.4 1.9 2 0 0 2 2 2 1 CBF/Mak21 family Myb_Cef PF11831.3 CDO68996.1 - 2.2e-61 207.0 0.0 2.2e-61 207.0 0.0 4.1 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 CDO68996.1 - 8.7e-22 76.9 5.9 8.3e-11 41.7 0.4 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO68996.1 - 3.9e-19 68.4 8.5 9e-13 48.1 2.5 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain V_ATPase_I PF01496.14 CDO68996.1 - 1 7.1 3.2 1.8 6.3 2.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3499 PF12005.3 CDO68996.1 - 1.9 8.6 6.6 0.31 11.2 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) DUF605 PF04652.11 CDO68997.1 - 0.054 12.9 12.4 0.071 12.4 8.6 1.2 1 0 0 1 1 1 0 Vta1 like DUF3609 PF12259.3 CDO68997.1 - 0.13 10.8 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF1690 PF07956.6 CDO68998.1 - 1e-18 67.6 3.6 2.4e-17 63.2 2.5 2.0 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF3220 PF11516.3 CDO68998.1 - 0.0095 15.9 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3120) DUF2317 PF10079.4 CDO68998.1 - 0.055 12.0 2.8 0.07 11.7 1.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) LMP PF04778.7 CDO68998.1 - 0.068 12.9 0.4 0.097 12.4 0.3 1.4 1 0 0 1 1 1 0 LMP repeated region APG6 PF04111.7 CDO68998.1 - 0.097 11.7 4.5 0.12 11.4 3.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 CDO68998.1 - 0.11 12.4 7.6 4.3 7.3 2.4 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TMF_TATA_bd PF12325.3 CDO68998.1 - 0.28 10.9 9.0 0.58 9.8 0.2 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Metal_resist PF13801.1 CDO68998.1 - 0.51 10.3 5.4 5.5 7.0 0.0 2.2 1 1 1 2 2 2 0 Heavy-metal resistance Histone_HNS PF00816.16 CDO68998.1 - 0.82 10.2 4.0 7.2 7.1 0.2 2.3 2 0 0 2 2 2 0 H-NS histone family HA2 PF04408.18 CDO68999.1 - 7.6e-18 64.4 0.0 1.5e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CDO68999.1 - 1.7e-11 43.9 0.0 3.9e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CDO68999.1 - 3.3e-08 33.2 0.0 7.3e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO68999.1 - 0.00097 18.6 0.0 0.0031 17.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Acetyltransf_2 PF00797.12 CDO68999.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 N-acetyltransferase DUF572 PF04502.8 CDO69000.1 - 2.1e-88 296.7 6.6 2.3e-88 296.5 4.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 CDO69000.1 - 0.017 14.7 1.1 0.37 10.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.8 CDO69000.1 - 0.027 13.9 0.1 0.049 13.1 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) HrpA_pilin PF09589.5 CDO69000.1 - 0.035 14.5 0.6 0.078 13.4 0.1 1.9 2 0 0 2 2 2 0 HrpA pilus formation protein Lar_restr_allev PF14354.1 CDO69000.1 - 0.094 13.0 0.5 7.6 6.9 1.0 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar eIF3_subunit PF08597.5 CDO69000.1 - 0.61 9.5 15.9 0.25 10.8 9.6 1.3 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit UQ_con PF00179.21 CDO69002.1 - 2.1e-44 150.3 0.0 2.6e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CDO69002.1 - 0.0018 18.1 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 CDO69002.1 - 0.0075 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF3684 PF12449.3 CDO69003.1 - 6.7e-72 242.5 0.0 8.3e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) DUF3684 PF12449.3 CDO69004.1 - 3.7e-243 809.6 0.0 2.3e-242 806.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3684) TGT PF01702.13 CDO69005.1 - 2.1e-27 95.9 0.0 1.8e-21 76.5 0.0 2.5 2 1 0 2 2 2 2 Queuine tRNA-ribosyltransferase DUF2156 PF09924.4 CDO69005.1 - 0.07 11.9 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) EF-hand_4 PF12763.2 CDO69006.1 - 1.1e-38 131.0 0.0 3e-15 55.8 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CDO69006.1 - 6.9e-13 48.5 0.0 3.1e-06 27.2 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CDO69006.1 - 7.5e-09 34.2 0.4 0.25 10.7 0.0 5.4 5 0 0 5 5 5 3 EF hand UBA PF00627.26 CDO69006.1 - 1.4e-08 34.3 0.0 3.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 CDO69006.1 - 5.8e-06 25.7 0.2 7.1 6.8 0.0 5.0 5 0 0 5 5 5 1 EF-hand domain EF-hand_8 PF13833.1 CDO69006.1 - 4.8e-05 22.8 0.0 0.69 9.5 0.0 4.3 4 0 0 4 4 4 1 EF-hand domain pair CENP-F_leu_zip PF10473.4 CDO69006.1 - 0.2 11.4 38.0 0.11 12.3 7.6 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 CDO69006.1 - 0.77 9.5 40.2 0.54 10.0 9.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 CDO69006.1 - 0.85 8.5 29.9 3.1e+02 0.0 20.8 2.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 CDO69006.1 - 6.7 5.2 31.9 1 7.9 6.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Sec8_exocyst PF04048.9 CDO69006.1 - 8.2 6.0 14.5 5.6 6.5 1.3 2.6 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Reo_sigmaC PF04582.7 CDO69006.1 - 9.1 5.3 10.4 8.4 5.4 3.5 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein PDEase_II PF02112.10 CDO69007.1 - 5.8e-41 140.5 0.0 9e-40 136.6 0.0 2.5 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 CDO69007.1 - 6.3e-09 35.6 0.0 8.9e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Corona_nucleoca PF00937.13 CDO69007.1 - 0.2 10.5 1.9 0.31 9.9 1.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein WD40 PF00400.27 CDO69008.1 - 1.5e-49 164.1 2.6 3.1e-10 39.5 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.7 CDO69008.1 - 1.8e-28 99.5 31.8 2.2e-27 95.9 16.8 3.4 2 1 0 2 2 2 1 Striatin family Nucleoporin_N PF08801.6 CDO69008.1 - 7.2e-05 21.7 0.0 0.0084 14.9 0.0 2.9 2 1 1 3 3 3 2 Nup133 N terminal like EF-hand_4 PF12763.2 CDO69009.1 - 1.9e-41 139.9 0.0 1.9e-10 40.4 0.0 4.3 4 0 0 4 4 4 4 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CDO69009.1 - 8.3e-14 51.4 0.0 5e-05 23.3 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 CDO69009.1 - 6.1e-10 37.6 0.0 0.11 11.8 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 CDO69009.1 - 6.8e-08 32.0 0.0 0.11 12.0 0.0 5.4 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.1 CDO69009.1 - 5.3e-06 25.8 3.0 1.9 8.6 0.0 5.7 6 0 0 6 6 6 2 EF-hand domain End3 PF12761.2 CDO69009.1 - 2.2e-05 24.1 0.1 0.0037 16.9 0.0 2.5 2 0 0 2 2 2 2 Actin cytoskeleton-regulatory complex protein END3 GAT PF03127.9 CDO69009.1 - 0.0002 21.2 1.5 0.00045 20.1 1.0 1.6 1 0 0 1 1 1 1 GAT domain R3H PF01424.17 CDO69010.1 - 1.5e-12 46.9 0.1 3.5e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 CDO69010.1 - 7.7e-08 32.2 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO69010.1 - 1.5e-07 30.8 0.0 3.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO69010.1 - 0.00016 21.4 0.1 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EcsC PF12787.2 CDO69010.1 - 0.045 13.1 0.1 0.071 12.4 0.1 1.2 1 0 0 1 1 1 0 EcsC protein family Endonuclease_NS PF01223.18 CDO69011.1 - 3e-52 177.2 0.0 3.8e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease MRP-L46 PF11788.3 CDO69012.1 - 1.5e-17 64.2 0.0 2.3e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 CDO69012.1 - 3.1e-10 39.8 0.0 5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PQQ PF01011.16 CDO69012.1 - 0.066 12.7 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat V-ATPase_H_N PF03224.9 CDO69013.1 - 1.5e-62 211.5 0.2 2.1e-51 174.9 0.0 2.5 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 CDO69013.1 - 3.4e-43 146.3 0.1 1.7e-42 144.1 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H HEAT PF02985.17 CDO69013.1 - 6e-07 29.0 0.4 0.0081 16.1 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.18 CDO69013.1 - 1.5e-05 24.5 0.6 2.7 7.9 0.0 4.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDO69013.1 - 1.6e-05 25.1 0.0 0.0097 16.1 0.0 3.2 2 2 0 2 2 2 1 HEAT repeats Arm_2 PF04826.8 CDO69013.1 - 3.6e-05 22.9 0.0 8.9e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Armadillo-like DUF2019 PF09450.5 CDO69013.1 - 0.01 15.6 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) HEAT_EZ PF13513.1 CDO69013.1 - 0.21 12.1 0.9 97 3.6 0.0 4.1 3 1 1 4 4 4 0 HEAT-like repeat p450 PF00067.17 CDO69014.1 - 5.3e-36 124.1 0.0 6.7e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nucleoporin_FG PF13634.1 CDO69016.1 - 0.0047 17.1 20.0 0.0047 17.1 13.9 11.3 3 2 7 10 10 10 6 Nucleoporin FG repeat region Tubulin PF00091.20 CDO69017.1 - 1.9e-74 250.1 0.0 3.1e-74 249.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CDO69017.1 - 3.3e-48 162.8 0.1 7.3e-48 161.7 0.1 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CDO69017.1 - 0.00039 20.4 0.0 0.0016 18.4 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CDO69017.1 - 0.0042 16.5 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain LGFP PF08310.6 CDO69017.1 - 0.12 12.0 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 LGFP repeat HTH_3 PF01381.17 CDO69018.1 - 9.6e-13 47.7 0.2 1.5e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 CDO69018.1 - 3.2e-07 30.2 0.0 4.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 CDO69018.1 - 5.2e-07 29.7 0.0 8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MBF1 PF08523.5 CDO69018.1 - 8e-06 25.7 4.4 0.045 13.7 0.0 2.9 2 2 1 3 3 3 2 Multiprotein bridging factor 1 HTH_25 PF13413.1 CDO69018.1 - 0.011 15.3 0.1 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Peptidase_M17 PF00883.16 CDO69019.1 - 1.4e-100 336.2 0.0 2.6e-100 335.2 0.0 1.4 1 1 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CDO69019.1 - 2e-06 27.5 0.8 4.5e-06 26.4 0.5 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain NAD_binding_7 PF13241.1 CDO69020.1 - 1.5e-31 108.6 0.0 8.8e-31 106.2 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CDO69020.1 - 1.7e-19 68.8 0.7 2.7e-19 68.2 0.5 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CDO69020.1 - 7.8e-14 50.3 0.2 1.2e-13 49.7 0.2 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 CDO69020.1 - 0.016 15.0 0.8 0.063 13.0 0.0 2.2 1 1 1 2 2 2 0 ThiF family DUF4191 PF13829.1 CDO69021.1 - 0.049 12.7 5.8 0.18 10.8 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF2919 PF11143.3 CDO69021.1 - 0.069 12.9 5.3 0.12 12.2 3.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) AMO PF02461.11 CDO69021.1 - 0.071 12.8 7.4 0.09 12.4 5.1 1.1 1 0 0 1 1 1 0 Ammonia monooxygenase DUF3953 PF13129.1 CDO69021.1 - 0.25 10.9 0.3 0.25 10.9 0.2 4.1 3 2 0 3 3 3 0 Protein of unknown function (DUF3953) DUF4013 PF13197.1 CDO69021.1 - 1.1 8.5 15.0 3.5 6.9 10.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4013) DUF4149 PF13664.1 CDO69021.1 - 1.1 9.3 8.0 12 6.0 2.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) RNA12 PF10443.4 CDO69022.1 - 4.2e-108 361.6 2.4 2.2e-107 359.2 1.6 2.1 1 1 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 CDO69022.1 - 1.2e-06 28.4 0.1 0.00093 18.9 0.0 2.5 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 CDO69022.1 - 2.1e-06 27.8 1.5 0.0002 21.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain cobW PF02492.14 CDO69022.1 - 0.0017 17.8 0.0 0.0064 15.9 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 CDO69022.1 - 0.0092 16.1 1.4 0.058 13.5 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CDO69022.1 - 0.018 14.9 0.0 0.059 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CDO69022.1 - 0.023 14.8 0.6 0.2 11.8 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CDO69022.1 - 0.044 13.5 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain NYD-SP28_assoc PF14775.1 CDO69022.1 - 0.12 12.0 2.2 0.38 10.4 0.3 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF974 PF06159.8 CDO69023.1 - 1.5e-62 211.3 0.0 2e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) p450 PF00067.17 CDO69024.1 - 9.8e-57 192.4 0.0 1.6e-56 191.8 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 DUF3321 PF11968.3 CDO69025.1 - 3.9e-61 206.4 0.0 5e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 CDO69025.1 - 0.00017 21.3 0.0 0.00062 19.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO69025.1 - 0.012 16.0 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CDO69025.1 - 0.025 15.0 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FAD-oxidase_C PF02913.14 CDO69026.1 - 1.4e-52 178.4 0.0 2.1e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CDO69026.1 - 8.5e-22 77.1 0.6 2.8e-20 72.2 0.4 2.5 1 1 0 1 1 1 1 FAD binding domain Ribosomal_L18e PF00828.14 CDO69027.1 - 2e-22 79.9 0.1 3.9e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Herpes_BLLF1 PF05109.8 CDO69027.1 - 1.1 7.0 5.5 1.5 6.6 3.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) 5_nucleotid_C PF02872.13 CDO69028.1 - 3.5e-19 69.3 0.0 5.2e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 CDO69028.1 - 4e-10 39.4 0.1 6.9e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDO69028.1 - 0.001 18.9 0.0 0.0026 17.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PGA_cap PF09587.5 CDO69028.1 - 0.0033 16.8 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Corona_nucleoca PF00937.13 CDO69028.1 - 6.6 5.5 9.9 2.6 6.9 0.6 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF543 PF04418.7 CDO69029.1 - 0.18 11.7 0.7 2.4 8.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Gly-zipper_YMGG PF13441.1 CDO69029.1 - 1.1 8.8 7.5 9.4 5.8 0.1 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 CDO69029.1 - 3.1 7.4 4.3 9.1 5.9 0.1 2.2 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Telomere_reg-2 PF10193.4 CDO69030.1 - 2.9e-21 75.8 0.0 5.7e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Telomere length regulation protein MFS_1 PF07690.11 CDO69031.1 - 5.5e-21 74.6 23.8 5.5e-21 74.6 16.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO69032.1 - 5e-77 259.3 8.9 6.7e-77 258.9 6.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO69032.1 - 1.5e-22 79.8 20.4 1.5e-22 79.8 14.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CDO69032.1 - 9.2e-08 30.8 24.0 5.2e-05 21.8 1.9 3.4 3 1 1 4 4 4 3 MFS/sugar transport protein TRI12 PF06609.8 CDO69032.1 - 0.00031 19.1 10.7 0.00045 18.5 3.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) CDC50 PF03381.10 CDO69033.1 - 1e-94 316.8 0.0 1.3e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family HOOK PF05622.7 CDO69034.1 - 3.8e-58 196.9 34.4 3.8e-58 196.9 23.8 3.2 1 1 2 3 3 3 2 HOOK protein TPR_MLP1_2 PF07926.7 CDO69034.1 - 0.00021 21.0 10.2 0.00021 21.0 7.0 7.6 5 1 3 8 8 8 4 TPR/MLP1/MLP2-like protein Filament PF00038.16 CDO69034.1 - 0.00026 20.5 11.5 0.00026 20.5 8.0 4.5 1 1 3 4 4 4 1 Intermediate filament protein NYD-SP28_assoc PF14775.1 CDO69034.1 - 0.0042 16.7 2.4 0.0042 16.7 1.6 6.2 5 1 0 5 5 5 1 Sperm tail C-terminal domain TSC22 PF01166.13 CDO69034.1 - 0.017 15.0 37.3 0.059 13.3 2.7 7.8 5 1 2 7 7 7 0 TSC-22/dip/bun family Reo_sigmaC PF04582.7 CDO69034.1 - 0.13 11.4 29.7 0.017 14.3 1.2 4.8 3 1 2 5 5 5 0 Reovirus sigma C capsid protein DUF3618 PF12277.3 CDO69034.1 - 6.3 6.9 27.2 1.9 8.6 1.9 5.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3618) RTC PF01137.16 CDO69035.1 - 4.1e-71 238.3 0.0 4.8e-71 238.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CDO69035.1 - 4.6e-22 77.9 0.2 7.9e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Alpha-amylase PF00128.19 CDO69036.1 - 3.8e-52 177.6 0.0 1.5e-51 175.7 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 CDO69036.1 - 1.1e-17 63.8 0.1 2.1e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) G-patch PF01585.18 CDO69037.1 - 3.6e-13 49.0 1.4 3.6e-13 49.0 1.0 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CDO69037.1 - 2.6e-07 30.3 0.6 2.6e-07 30.3 0.4 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_1 PF00076.17 CDO69037.1 - 6.9e-05 22.4 0.0 0.0049 16.4 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO69037.1 - 0.00024 20.9 0.0 0.049 13.6 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO69037.1 - 0.0029 17.4 0.0 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 CDO69037.1 - 0.0097 15.1 3.0 0.022 13.9 2.1 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region zf-C2H2_jaz PF12171.3 CDO69037.1 - 0.01 15.9 0.5 0.021 14.9 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ROS_MUCR PF05443.6 CDO69037.1 - 0.018 14.8 0.1 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein zf-C2H2_2 PF12756.2 CDO69037.1 - 0.049 13.7 0.3 0.093 12.8 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) NDUF_B4 PF07225.7 CDO69038.1 - 0.0016 18.2 0.0 0.0018 18.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) COQ7 PF03232.8 CDO69039.1 - 3.7e-66 221.8 0.0 4.5e-66 221.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ferritin_2 PF13668.1 CDO69039.1 - 0.027 14.4 0.1 2.9 7.8 0.0 2.3 1 1 1 2 2 2 0 Ferritin-like domain WD40 PF00400.27 CDO69041.1 - 9.4e-48 158.4 21.4 4.5e-10 39.0 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 CDO69041.1 - 1.6e-12 46.9 0.2 3.5e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO69041.1 - 4e-10 39.0 0.1 8e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 CDO69041.1 - 1.2e-06 27.0 9.9 0.016 13.3 0.1 4.7 2 2 3 5 5 5 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 CDO69041.1 - 0.084 12.6 0.1 13 5.6 0.0 3.6 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 CDO69042.1 - 5.7e-62 209.2 0.0 6.7e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69042.1 - 8.9e-25 87.2 0.0 1.3e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO69042.1 - 0.0007 18.6 0.0 0.0017 17.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CDO69042.1 - 0.0021 17.8 0.1 0.029 14.1 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO69042.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase COG4 PF08318.7 CDO69043.1 - 9.3e-47 159.3 0.0 3.1e-46 157.6 0.0 1.9 1 1 0 1 1 1 1 COG4 transport protein DUF1664 PF07889.7 CDO69043.1 - 0.045 13.5 0.1 0.16 11.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RINT1_TIP1 PF04437.8 CDO69043.1 - 0.048 12.2 0.0 0.091 11.2 0.0 1.4 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Snf7 PF03357.16 CDO69044.1 - 4.5e-35 120.5 16.8 1.3e-34 119.1 9.9 2.5 2 1 0 2 2 2 1 Snf7 YlqD PF11068.3 CDO69044.1 - 0.019 15.0 8.2 0.048 13.6 0.3 2.4 2 1 0 2 2 2 0 YlqD protein Resolvase PF00239.16 CDO69044.1 - 0.68 9.7 7.5 0.82 9.5 0.8 2.5 2 1 0 2 2 2 0 Resolvase, N terminal domain DUF4208 PF13907.1 CDO69044.1 - 0.91 9.7 5.0 8.5 6.6 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4208) CDC37_N PF03234.9 CDO69044.1 - 1.2 9.4 7.3 4.1 7.6 0.7 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF2203 PF09969.4 CDO69044.1 - 1.6 8.9 5.5 7.6 6.7 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) zf-AN1 PF01428.11 CDO69045.1 - 7.3e-17 60.9 14.0 3.5e-09 36.3 1.2 2.6 2 1 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 CDO69045.1 - 0.011 15.6 2.0 0.011 15.6 1.4 2.5 2 0 0 2 2 2 0 IBR domain Fer4_21 PF14697.1 CDO69045.1 - 9.9 6.1 8.7 0.8 9.6 1.0 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Myosin_head PF00063.16 CDO69046.1 - 2e-241 802.8 0.0 2e-241 802.8 0.0 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 CDO69046.1 - 5.4e-34 116.2 1.6 5.4e-34 116.2 1.1 2.6 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 CDO69046.1 - 5.2e-15 53.5 39.6 0.00065 19.1 0.6 7.6 7 0 0 7 7 7 6 IQ calmodulin-binding motif AAA_22 PF13401.1 CDO69046.1 - 0.0034 17.5 0.0 0.039 14.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.14 CDO69046.1 - 0.0084 15.7 0.2 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Fib_alpha PF08702.5 CDO69046.1 - 0.086 12.9 11.2 0.42 10.7 7.8 2.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Bestrophin PF01062.16 CDO69047.1 - 4.7e-39 134.0 0.1 9.6e-23 80.5 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel 2Fe-2S_thioredx PF01257.14 CDO69048.1 - 6.9e-58 194.3 0.0 8.8e-58 194.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DDE_3 PF13358.1 CDO69049.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO69049.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_1 PF03184.14 CDO69050.1 - 3.2e-19 68.9 0.0 1.3e-18 66.9 0.0 2.1 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CDO69050.1 - 1.4e-10 40.8 0.2 1.7e-09 37.3 0.0 2.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain TPP_enzyme_N PF02776.13 CDO69055.1 - 2.4e-38 131.3 0.2 4.3e-38 130.5 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CDO69055.1 - 4.8e-26 91.1 0.0 1e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CDO69055.1 - 9.2e-14 51.2 0.0 2.5e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ras PF00071.17 CDO69058.1 - 4.5e-34 117.1 0.2 5.4e-34 116.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO69058.1 - 7.8e-23 81.2 0.1 5.3e-22 78.5 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CDO69058.1 - 3.4e-08 32.9 0.1 5.4e-08 32.2 0.0 1.4 1 1 1 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO69058.1 - 3.9e-08 32.7 0.2 4.8e-08 32.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CDO69058.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 CDO69058.1 - 0.017 13.8 0.7 0.056 12.1 0.0 2.0 1 1 2 3 3 3 0 G-protein alpha subunit DLIC PF05783.6 CDO69058.1 - 0.08 11.5 0.1 6.8 5.2 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Glyco_hydro_18 PF00704.23 CDO69059.1 - 8.3e-85 285.2 18.7 1.5e-84 284.4 8.2 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 CDO69059.1 - 5.6e-12 45.0 13.6 1.7e-11 43.4 9.4 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain CBM_5_12_2 PF14600.1 CDO69059.1 - 0.0019 17.8 5.5 0.0096 15.5 3.8 2.3 1 0 0 1 1 1 1 Cellulose-binding domain Glyco_hydro_18 PF00704.23 CDO69060.1 - 2.1e-90 303.6 11.4 2.1e-90 303.6 7.9 2.5 2 1 1 3 3 3 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 CDO69060.1 - 2e-12 46.4 15.6 5.9e-12 44.9 10.8 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain DUF605 PF04652.11 CDO69060.1 - 0.3 10.4 21.9 0.5 9.7 15.2 1.3 1 0 0 1 1 1 0 Vta1 like DUF936 PF06075.7 CDO69060.1 - 0.63 8.8 25.5 0.81 8.5 17.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) rRNA_proc-arch PF13234.1 CDO69061.1 - 1e-97 326.5 0.0 1.6e-97 325.8 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 CDO69061.1 - 1.1e-61 207.1 0.6 2.8e-61 205.9 0.4 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CDO69061.1 - 1.2e-16 60.6 0.2 1.6e-14 53.7 0.0 2.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO69061.1 - 3.6e-07 29.9 0.0 9.1e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 CDO69061.1 - 0.02 13.8 0.0 0.051 12.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein CBM_20 PF00686.14 CDO69062.1 - 1.2e-32 111.3 0.2 2.2e-32 110.5 0.2 1.5 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.19 CDO69062.1 - 3.6e-20 72.5 0.0 1.2e-19 70.9 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 CDO69062.1 - 6.1e-12 45.5 0.0 1.7e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain DUF2457 PF10446.4 CDO69063.1 - 0.94 8.1 7.7 0.32 9.6 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) FAD_binding_3 PF01494.14 CDO69064.1 - 3.3e-75 253.3 0.0 4.5e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CDO69064.1 - 2.3e-09 36.6 0.5 2.2e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 CDO69064.1 - 4.7e-07 28.6 1.6 4.7e-06 25.3 0.2 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 CDO69064.1 - 1.4e-06 27.4 1.5 1.4e-06 27.4 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CDO69064.1 - 1.5e-06 27.5 0.1 2.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 CDO69064.1 - 3.5e-06 27.3 2.6 0.034 14.5 0.2 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO69064.1 - 4.1e-06 26.7 0.2 1e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CDO69064.1 - 9.6e-06 25.7 0.0 6.5e-05 23.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDO69064.1 - 1.2e-05 25.3 0.1 4.9e-05 23.3 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CDO69064.1 - 3.1e-05 22.7 0.1 6.4e-05 21.7 0.1 1.5 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.2 CDO69064.1 - 0.00017 20.8 2.8 0.00058 19.0 1.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 CDO69064.1 - 0.00068 18.6 0.8 0.0011 17.8 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 CDO69064.1 - 0.0044 16.8 2.8 0.16 11.7 0.1 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CDO69064.1 - 0.0062 15.4 0.2 0.017 14.0 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 CDO69064.1 - 0.028 14.6 0.1 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 CDO69064.1 - 0.038 13.4 1.4 0.35 10.3 0.2 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Tocopherol_cycl PF14249.1 CDO69066.1 - 4.5e-07 28.8 0.1 1.5e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Tocopherol cyclase Cys_Met_Meta_PP PF01053.15 CDO69068.1 - 7.1e-49 166.1 0.3 4.3e-33 114.1 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CDO69068.1 - 0.0013 17.8 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family FMN_red PF03358.10 CDO69069.1 - 5.1e-07 29.3 0.0 7.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 CDO69069.1 - 1.5e-05 25.0 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 CDO69069.1 - 9.9e-05 21.9 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold COG7 PF10191.4 CDO69070.1 - 7.3e-75 252.3 0.0 6.7e-47 159.9 0.5 3.1 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) Vps53_N PF04100.7 CDO69070.1 - 0.033 12.9 0.6 0.064 12.0 0.4 1.4 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF2450 PF10475.4 CDO69070.1 - 0.066 12.1 0.8 4.1 6.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) DUF3100 PF11299.3 CDO69070.1 - 0.2 10.8 0.7 0.45 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3100) eIF3g PF12353.3 CDO69071.1 - 4.1e-28 97.8 2.5 1.1e-26 93.2 0.3 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CDO69071.1 - 6.2e-19 67.3 0.1 1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO69071.1 - 8.4e-17 60.9 0.0 1.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO69071.1 - 8.3e-11 41.5 0.0 1.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CDO69071.1 - 0.00025 20.8 0.3 0.048 13.5 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Vma12 PF11712.3 CDO69072.1 - 1.1 8.8 5.2 1.7 8.3 0.3 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase 7tm_6 PF02949.15 CDO69072.1 - 9.9 4.9 13.9 0.26 10.1 5.0 1.7 2 0 0 2 2 2 0 7tm Odorant receptor Rad60-SLD_2 PF13881.1 CDO69074.1 - 1.6e-12 47.3 0.0 2.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CDO69074.1 - 0.00017 20.8 0.0 0.0012 18.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 CDO69074.1 - 0.064 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PGI PF00342.14 CDO69075.1 - 2e-216 719.1 0.1 2.3e-216 718.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Cu_amine_oxid PF01179.15 CDO69076.1 - 9.2e-103 344.1 0.0 1.3e-102 343.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 CDO69076.1 - 5.9e-10 38.9 0.0 1.6e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Pro-kuma_activ PF09286.6 CDO69077.1 - 9.7e-36 122.9 0.0 1.8e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO69077.1 - 1.9e-07 30.5 0.0 3.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Epimerase PF01370.16 CDO69078.1 - 2.2e-12 46.9 0.0 5e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CDO69078.1 - 2.7e-10 39.6 0.0 5e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CDO69078.1 - 1.6e-08 34.7 0.5 2e-05 24.6 0.1 2.2 2 0 0 2 2 2 2 NADH(P)-binding 3Beta_HSD PF01073.14 CDO69078.1 - 2.2e-06 26.6 0.1 0.0028 16.4 0.0 2.3 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CDO69078.1 - 0.0015 17.8 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CDO69078.1 - 0.0028 17.5 1.0 0.048 13.5 0.7 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO69078.1 - 0.0049 16.5 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 CDO69079.1 - 2.1e-14 53.5 0.0 1.6e-13 50.6 0.0 2.2 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO69079.1 - 6.3e-13 48.0 0.0 1.1e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CDO69079.1 - 3.7e-11 43.3 0.2 7.6e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CDO69079.1 - 4.4e-07 29.0 0.1 3.6e-06 26.0 0.1 2.4 3 1 0 3 3 3 1 Male sterility protein NmrA PF05368.8 CDO69079.1 - 0.00021 20.6 0.1 0.00031 20.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CDO69079.1 - 0.00059 19.7 0.2 0.0025 17.7 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CDO69079.1 - 0.017 14.7 0.1 0.041 13.5 0.1 1.7 1 1 0 1 1 1 0 KR domain Citrate_synt PF00285.16 CDO69080.1 - 3.8e-18 65.3 0.0 3.2e-16 59.0 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 CDO69080.1 - 2e-07 31.4 0.0 4.3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 CDO69080.1 - 3.1e-07 29.9 0.0 5.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain DUF1275 PF06912.6 CDO69081.1 - 5.5e-21 74.7 18.5 8.2e-21 74.1 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) NAD_binding_10 PF13460.1 CDO69082.1 - 9.1e-12 45.3 0.5 8.7e-11 42.1 0.2 2.1 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CDO69082.1 - 6.7e-11 42.0 0.0 9.8e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO69082.1 - 4.6e-06 25.5 0.0 6.5e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CDO69082.1 - 0.0025 16.8 0.0 0.1 11.5 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 CDO69082.1 - 0.0034 16.6 0.0 0.0063 15.7 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CDO69083.1 - 5.2e-18 65.3 0.1 6.8e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO69083.1 - 5.1e-14 51.6 0.0 7.1e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CDO69083.1 - 2.2e-13 50.6 1.2 3.7e-13 49.8 0.8 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CDO69083.1 - 1.8e-09 36.8 0.2 5.9e-09 35.2 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 CDO69083.1 - 2.1e-06 27.1 0.1 3.8e-06 26.3 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CDO69083.1 - 9.6e-05 22.3 0.4 0.0013 18.6 0.3 2.3 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CDO69083.1 - 0.00018 20.5 0.1 0.00027 19.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 CDO69083.1 - 0.018 14.7 0.7 0.29 10.7 0.5 2.3 1 1 0 1 1 1 0 KR domain Epimerase PF01370.16 CDO69084.1 - 4.2e-18 65.6 0.0 6.2e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO69084.1 - 1.9e-14 53.0 0.0 2.8e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CDO69084.1 - 3.4e-12 46.7 1.0 6.1e-12 45.9 0.7 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CDO69084.1 - 5.4e-11 41.8 0.1 1.4e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 CDO69084.1 - 6.6e-07 28.8 0.2 9.8e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CDO69084.1 - 0.00013 21.8 0.9 0.0011 18.9 0.6 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CDO69084.1 - 0.00018 20.5 0.3 0.00026 19.9 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 CDO69084.1 - 0.018 14.7 0.6 0.14 11.8 0.4 2.1 1 1 0 1 1 1 0 KR domain Peptidase_M64 PF09471.5 CDO69084.1 - 0.073 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 IgA Peptidase M64 Pkinase PF00069.20 CDO69085.1 - 1.4e-52 178.3 0.0 2.4e-52 177.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69085.1 - 4.1e-25 88.3 0.0 3.6e-16 59.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CDO69085.1 - 0.00064 19.5 0.1 0.0047 16.6 0.1 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CDO69085.1 - 0.00085 18.3 0.0 0.002 17.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CDO69085.1 - 0.22 10.2 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pro-kuma_activ PF09286.6 CDO69086.1 - 9.4e-35 119.7 0.0 2e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO69086.1 - 3.3e-09 36.3 0.4 5.4e-09 35.6 0.3 1.3 1 0 0 1 1 1 1 Subtilase family F-box-like PF12937.2 CDO69087.1 - 7.8e-09 35.1 2.9 2.3e-08 33.6 2.0 1.9 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 CDO69089.1 - 2.6e-17 62.5 25.2 2.7e-17 62.5 16.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO69089.1 - 1.3e-16 59.9 4.6 1.3e-16 59.9 3.2 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_6 PF12697.2 CDO69090.1 - 9.5e-21 74.7 0.2 1.2e-20 74.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO69090.1 - 1.7e-15 57.0 0.0 2.8e-15 56.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO69090.1 - 1.6e-13 50.2 0.4 3.5e-13 49.1 0.3 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CDO69090.1 - 9.7e-07 28.5 0.1 2.4e-06 27.2 0.1 1.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.7 CDO69090.1 - 3.2e-05 23.3 0.1 0.00011 21.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF1749 PF08538.5 CDO69090.1 - 6.9e-05 21.8 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Lipase_3 PF01764.20 CDO69090.1 - 0.00027 20.5 0.1 0.002 17.7 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 CDO69090.1 - 0.00058 19.5 0.0 0.037 13.6 0.0 2.5 2 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_2 PF02230.11 CDO69090.1 - 0.0045 16.4 0.0 3.1 7.1 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF3089 PF11288.3 CDO69090.1 - 0.0061 15.7 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_3 PF07859.8 CDO69090.1 - 0.041 13.4 0.9 0.066 12.7 0.0 1.8 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDO69090.1 - 0.049 12.8 0.0 5.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2305 PF10230.4 CDO69090.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) YqzM PF14141.1 CDO69091.1 - 0.03 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 YqzM-like protein SUR7 PF06687.7 CDO69091.1 - 0.037 13.5 1.7 0.049 13.1 1.2 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF368 PF04018.8 CDO69091.1 - 0.075 12.2 0.2 0.088 11.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF368) PHA_gran_rgn PF09650.5 CDO69091.1 - 0.088 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) BCS1_N PF08740.6 CDO69092.1 - 1.9e-14 53.6 1.2 3.5e-08 33.3 0.1 2.3 1 1 1 2 2 2 2 BCS1 N terminal AAA PF00004.24 CDO69092.1 - 1.3e-11 44.7 0.0 2e-10 40.9 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDO69092.1 - 0.00066 18.8 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CDO69092.1 - 0.0014 18.6 0.3 0.0078 16.2 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 CDO69092.1 - 0.0024 17.0 0.0 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 CDO69092.1 - 0.0087 15.9 0.0 0.025 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 CDO69092.1 - 0.0096 14.8 0.0 0.041 12.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CDO69092.1 - 0.039 14.7 0.0 0.11 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CDO69092.1 - 0.049 13.1 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CDO69092.1 - 0.062 13.0 0.0 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 CDO69092.1 - 0.071 12.7 0.0 0.35 10.5 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 CDO69092.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CDO69092.1 - 0.085 12.2 0.8 0.54 9.6 0.0 2.4 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.17 CDO69092.1 - 0.14 12.3 0.0 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.8 CDO69092.1 - 0.27 9.9 0.0 0.43 9.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Pantoate_ligase PF02569.10 CDO69093.1 - 5.3e-38 130.3 0.0 7.8e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase UCR_Fe-S_N PF10399.4 CDO69093.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Glyco_hydro_71 PF03659.9 CDO69094.1 - 3.2e-65 220.0 16.6 2.1e-59 200.9 11.5 4.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 LANC_like PF05147.8 CDO69095.1 - 2.2e-11 42.9 0.1 5.8e-10 38.2 0.0 2.5 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Glyoxal_oxid_N PF07250.6 CDO69096.1 - 5.6e-33 114.0 0.1 6e-31 107.3 0.0 3.2 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CDO69096.1 - 2.6e-21 75.5 0.1 5e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Herpes_gE PF02480.11 CDO69096.1 - 0.0017 16.7 0.0 0.0025 16.1 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Kelch_4 PF13418.1 CDO69096.1 - 0.04 13.6 6.7 0.14 11.9 0.1 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain Abhydrolase_5 PF12695.2 CDO69097.1 - 1.5e-08 34.4 0.0 3e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO69097.1 - 2.7e-07 30.7 0.0 4.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CDO69097.1 - 0.00048 19.3 0.0 0.0012 18.1 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 CDO69097.1 - 0.014 15.2 0.1 0.17 11.7 0.1 2.2 1 1 0 1 1 1 0 Putative lysophospholipase PhoPQ_related PF10142.4 CDO69097.1 - 0.085 11.3 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Peptidase_S37 PF05576.6 CDO69097.1 - 0.099 11.0 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 MFS_1 PF07690.11 CDO69098.1 - 8.5e-17 60.8 33.0 1.2e-07 30.7 18.2 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CDO69098.1 - 3.4e-10 38.7 5.0 3.4e-10 38.7 3.5 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PIP5K PF01504.13 CDO69100.1 - 9.2e-88 293.5 0.1 1.3e-87 293.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cnd1 PF12717.2 CDO69101.1 - 4.8e-60 202.4 5.7 3.5e-58 196.3 0.2 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 CDO69101.1 - 4.2e-47 159.9 0.5 4.2e-47 159.9 0.3 3.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 CDO69101.1 - 3.5e-10 40.0 3.6 0.0062 16.7 0.0 5.3 4 1 1 5 5 5 2 HEAT repeats Adaptin_N PF01602.15 CDO69101.1 - 8.3e-06 24.4 6.6 0.0028 16.0 0.1 4.0 3 2 1 5 5 5 3 Adaptin N terminal region HEAT PF02985.17 CDO69101.1 - 0.00012 21.8 10.9 0.48 10.6 0.1 6.6 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 CDO69101.1 - 0.0022 18.4 9.1 13 6.3 0.0 6.4 6 1 1 7 7 7 2 HEAT-like repeat FKS1_dom1 PF14288.1 CDO69101.1 - 0.023 14.6 0.0 0.078 12.8 0.0 1.9 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 PqqD PF05402.7 CDO69101.1 - 0.04 13.9 0.1 0.33 10.9 0.0 2.6 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) YtzH PF14165.1 CDO69101.1 - 0.047 13.9 1.2 1.8 8.8 0.0 4.1 3 1 1 4 4 4 0 YtzH-like protein RNA_pol_N PF01194.12 CDO69102.1 - 2.2e-30 104.4 0.3 2.6e-30 104.2 0.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Oxidored_FMN PF00724.15 CDO69103.1 - 3.2e-27 95.4 0.0 3.4e-20 72.3 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 CDO69103.1 - 0.014 14.2 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Nitro_FeMo-Co PF02579.12 CDO69103.1 - 0.031 14.3 0.2 1.7 8.7 0.0 2.8 2 1 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor FMN_dh PF01070.13 CDO69103.1 - 0.044 12.6 0.7 0.063 12.1 0.5 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase adh_short PF00106.20 CDO69104.1 - 5.9e-10 39.3 0.0 9.1e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.20 CDO69105.1 - 1.7e-17 63.8 1.0 1.7e-15 57.3 0.7 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO69105.1 - 7.7e-06 25.6 0.4 0.00025 20.7 0.1 2.1 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 CDO69105.1 - 0.00066 19.5 0.0 0.002 17.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO69106.1 - 8.8e-26 90.7 0.2 1.1e-25 90.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO69106.1 - 2.1e-11 43.8 0.1 2.7e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO69106.1 - 0.00062 19.2 0.0 0.00076 18.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CDO69106.1 - 0.0025 16.7 0.0 0.0062 15.4 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CDO69106.1 - 0.0031 17.5 0.0 0.016 15.1 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 CDO69107.1 - 3e-16 59.7 0.6 7.1e-14 52.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CDO69107.1 - 2.5e-07 30.5 0.1 6.2e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 CDO69107.1 - 0.00018 21.5 0.1 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CDO69107.1 - 0.00019 20.9 0.0 0.00041 19.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CDO69107.1 - 0.0065 15.4 0.1 0.042 12.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 CDO69107.1 - 0.0085 14.8 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CDO69107.1 - 0.044 12.6 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F-box-like PF12937.2 CDO69108.1 - 0.00031 20.4 0.3 0.00089 18.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO69108.1 - 0.00077 19.0 0.3 0.0018 17.8 0.2 1.6 1 0 0 1 1 1 1 F-box domain AAA_12 PF13087.1 CDO69109.1 - 1.4e-35 122.4 0.1 2.8e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDO69109.1 - 4.4e-28 98.4 0.0 5.4e-27 94.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO69109.1 - 1.2e-09 37.7 0.0 4.8e-09 35.8 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CDO69109.1 - 7.3e-09 35.4 0.0 4.5e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain zf-CCCH PF00642.19 CDO69109.1 - 0.0001 21.8 6.6 0.0001 21.8 4.6 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UvrD_C_2 PF13538.1 CDO69109.1 - 0.00054 20.0 0.0 0.002 18.2 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain zf-RING_2 PF13639.1 CDO69109.1 - 0.00067 19.4 0.2 0.00067 19.4 0.1 2.6 2 0 0 2 2 2 1 Ring finger domain UvrD-helicase PF00580.16 CDO69109.1 - 0.0041 16.4 0.1 0.029 13.6 0.0 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 CDO69109.1 - 0.0065 15.4 0.0 0.45 9.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 CDO69109.1 - 0.027 14.7 0.0 0.1 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CDO69109.1 - 0.029 13.4 0.0 0.071 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA PF00004.24 CDO69109.1 - 0.031 14.4 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CDO69109.1 - 0.054 13.3 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDO69109.1 - 0.095 13.5 0.2 0.66 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain zf-CCCH_2 PF14608.1 CDO69109.1 - 0.2 11.7 6.2 0.093 12.7 1.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF1319 PF07028.6 CDO69109.1 - 0.57 10.3 3.4 0.68 10.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) Glyco_hydro_10 PF00331.15 CDO69110.1 - 7.2e-88 294.6 0.0 8.4e-88 294.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 adh_short PF00106.20 CDO69111.1 - 2.8e-22 79.4 0.5 3.7e-22 78.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO69111.1 - 6.7e-10 38.9 0.1 8.5e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 CDO69111.1 - 0.1 12.1 0.0 0.34 10.4 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.20 CDO69112.1 - 6.3e-21 75.0 0.1 7.9e-21 74.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO69112.1 - 7.4e-09 35.7 0.0 8.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO69112.1 - 1.1e-08 35.0 0.2 1.8e-08 34.2 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CDO69112.1 - 0.0009 19.2 0.0 0.0057 16.6 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CDO69112.1 - 0.0016 17.9 0.1 0.0027 17.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CDO69112.1 - 0.011 14.7 0.0 0.014 14.3 0.0 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 CDO69112.1 - 0.043 13.3 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NmrA PF05368.8 CDO69112.1 - 0.11 11.7 0.1 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Saccharop_dh PF03435.13 CDO69112.1 - 0.15 11.0 0.2 0.45 9.4 0.1 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase APH PF01636.18 CDO69113.1 - 3.8e-05 23.5 0.3 0.00012 21.8 0.2 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family NMD3 PF04981.8 CDO69114.1 - 1.2e-74 250.4 0.3 1.5e-74 250.0 0.2 1.1 1 0 0 1 1 1 1 NMD3 family Rpr2 PF04032.11 CDO69114.1 - 0.005 16.6 1.2 0.83 9.5 0.1 2.6 1 1 0 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 CDO69114.1 - 0.026 14.3 5.0 0.043 13.6 1.8 2.4 2 1 0 2 2 2 0 Double zinc ribbon DNA_pol3_delta2 PF13177.1 CDO69114.1 - 0.027 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF1289 PF06945.8 CDO69114.1 - 0.095 12.1 0.0 19 4.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) NinF PF05810.7 CDO69114.1 - 0.14 11.9 1.7 0.49 10.2 0.7 2.2 2 0 0 2 2 2 0 NinF protein zf-C3HC4_3 PF13920.1 CDO69114.1 - 4.9 6.8 6.3 0.38 10.4 0.3 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CLN3 PF02487.12 CDO69115.1 - 8.1e-27 94.0 0.0 2.6e-26 92.3 0.0 1.6 1 1 0 1 1 1 1 CLN3 protein DUF3755 PF12579.3 CDO69117.1 - 0.0052 16.1 0.2 0.21 11.0 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3755) DUF722 PF05263.6 CDO69117.1 - 0.023 14.8 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Bim_N PF06773.6 CDO69118.1 - 0.036 13.8 3.3 0.1 12.3 2.3 1.8 1 0 0 1 1 1 0 Bim protein N-terminus rve PF00665.21 CDO69119.1 - 2.5e-15 56.6 0.0 6.7e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 CDO69119.1 - 6.2e-14 51.5 0.0 1.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO69119.1 - 4e-11 42.7 0.0 7.2e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO69119.1 - 8.8e-09 34.8 0.0 1.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_3 PF14244.1 CDO69119.1 - 2.9e-08 33.4 0.0 5.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO69119.1 - 2.2e-07 30.1 0.6 1.7e-06 27.2 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 CDO69119.1 - 0.011 15.6 4.6 0.011 15.6 3.2 2.1 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDO69119.1 - 0.034 13.7 1.9 0.067 12.8 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle ING PF12998.2 CDO69121.1 - 3e-14 53.1 0.2 3.5e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CDO69121.1 - 1.4e-05 24.6 6.4 0.0027 17.3 0.6 2.4 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 CDO69121.1 - 0.0018 17.5 1.9 0.0035 16.6 1.3 1.5 1 0 0 1 1 1 1 PHD-finger Nuf2 PF03800.9 CDO69122.1 - 1.1e-33 116.2 0.4 3.9e-33 114.5 0.0 2.1 2 0 0 2 2 2 1 Nuf2 family DUF3584 PF12128.3 CDO69122.1 - 0.0024 15.3 35.2 0.0032 14.9 24.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TMF_DNA_bd PF12329.3 CDO69122.1 - 0.03 14.1 2.1 0.03 14.1 1.5 5.4 3 2 3 6 6 6 0 TATA element modulatory factor 1 DNA binding Sec34 PF04136.10 CDO69122.1 - 0.036 13.7 0.5 0.036 13.7 0.3 3.1 2 2 1 3 3 3 0 Sec34-like family Filament PF00038.16 CDO69122.1 - 0.12 11.8 37.7 1.3 8.4 2.3 3.1 1 1 2 3 3 3 0 Intermediate filament protein DUF972 PF06156.8 CDO69122.1 - 0.54 10.6 25.5 1.1 9.6 1.7 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF972) HALZ PF02183.13 CDO69122.1 - 3.8 7.2 14.3 11 5.7 0.0 4.5 4 1 0 4 4 4 0 Homeobox associated leucine zipper APG6 PF04111.7 CDO69122.1 - 5.1 6.0 36.3 0.063 12.3 5.7 2.9 1 1 1 3 3 3 0 Autophagy protein Apg6 IncA PF04156.9 CDO69122.1 - 6.6 6.2 35.6 3.1 7.3 10.8 2.6 1 1 1 2 2 2 0 IncA protein Helicase_C PF00271.26 CDO69123.1 - 1e-16 60.5 0.0 2.5e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO69123.1 - 6.1e-16 58.3 0.0 4.7e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 CDO69123.1 - 9.2e-13 47.8 0.0 2.5e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 RQC domain DUF1156 PF06634.7 CDO69126.1 - 0.019 14.6 0.3 0.033 13.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) Flavi_M PF01004.14 CDO69126.1 - 0.057 12.8 0.7 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M Retrotrans_gag PF03732.12 CDO69127.1 - 1.7e-08 34.4 0.0 3.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein LSM PF01423.17 CDO69129.1 - 7.7e-13 47.7 0.3 1.2e-12 47.1 0.2 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CDO69129.1 - 0.045 13.6 0.0 0.073 12.9 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Voltage_CLC PF00654.15 CDO69130.1 - 2e-72 244.1 23.6 5.5e-71 239.4 14.6 2.5 2 1 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 CDO69130.1 - 0.0023 17.6 0.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 CBS domain E1-E2_ATPase PF00122.15 CDO69130.1 - 0.24 10.4 0.0 0.24 10.4 0.0 2.1 2 1 0 2 2 2 0 E1-E2 ATPase DUF3506 PF12014.3 CDO69131.1 - 8.7e-10 38.5 0.0 2.2e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.28 CDO69131.1 - 0.0027 17.3 0.3 0.005 16.4 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO69131.1 - 0.019 14.6 0.2 0.048 13.3 0.2 1.7 1 0 0 1 1 1 0 F-box-like UBN2_2 PF14227.1 CDO69132.1 - 7.2e-06 25.5 0.0 5.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO69132.1 - 0.0037 17.1 4.6 0.0037 17.1 3.2 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 CDO69132.1 - 0.011 15.3 2.1 0.019 14.6 1.5 1.3 1 0 0 1 1 1 0 Zinc knuckle UBN2 PF14223.1 CDO69132.1 - 0.017 14.9 0.1 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO69132.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Abhydrolase_1 PF00561.15 CDO69133.1 - 1e-12 48.1 0.1 5.9e-09 35.8 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDO69133.1 - 7.5e-08 32.5 0.1 1.2e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO69133.1 - 0.038 13.7 0.0 0.24 11.1 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribosom_S12_S23 PF00164.20 CDO69134.1 - 1.3e-39 134.4 1.1 1.5e-39 134.1 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CTP_transf_1 PF01148.15 CDO69135.1 - 1.6e-74 250.8 24.2 2.1e-74 250.4 16.8 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2839 PF10999.3 CDO69135.1 - 0.033 14.2 0.1 0.095 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) UPF0233 PF06781.7 CDO69135.1 - 0.36 10.4 8.4 0.68 9.5 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Di19_C PF14571.1 CDO69135.1 - 0.59 10.4 3.4 0.28 11.4 0.1 2.0 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Topoisom_I_N PF02919.10 CDO69136.1 - 5e-98 326.6 0.5 5e-98 326.6 0.3 3.6 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CDO69136.1 - 1.1e-69 234.0 9.9 3.3e-49 167.1 0.5 3.2 2 2 2 4 4 4 2 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CDO69136.1 - 9.5e-33 111.6 2.2 1e-32 111.5 0.2 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain NDUF_B12 PF08122.7 CDO69137.1 - 3.4e-18 65.1 0.6 4.4e-18 64.7 0.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family PALP PF00291.20 CDO69138.1 - 7.6e-77 258.5 0.2 1.3e-76 257.7 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 CDO69138.1 - 8.6e-46 153.4 0.0 6.9e-27 92.8 0.0 2.5 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase PHD PF00628.24 CDO69138.1 - 7.6e-09 35.1 10.6 1.4e-08 34.3 7.3 1.4 1 0 0 1 1 1 1 PHD-finger DUF4559 PF15112.1 CDO69138.1 - 0.24 10.5 3.7 0.44 9.6 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Vps8 PF12816.2 CDO69139.1 - 4.5e-67 225.0 0.0 3.1e-65 219.1 0.0 2.6 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 CDO69139.1 - 0.00019 21.0 0.0 0.047 13.3 0.0 3.2 3 0 0 3 3 3 1 Region in Clathrin and VPS COG2 PF06148.6 CDO69140.1 - 1.1e-29 102.9 2.7 3.9e-29 101.1 1.9 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 CDO69140.1 - 3.4e-19 69.1 1.0 2e-18 66.7 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3510) Spc7 PF08317.6 CDO69140.1 - 0.0023 16.6 1.5 0.0044 15.7 1.0 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Vps51 PF08700.6 CDO69140.1 - 0.0024 17.6 0.4 0.0095 15.7 0.3 2.1 1 0 0 1 1 1 1 Vps51/Vps67 IncA PF04156.9 CDO69140.1 - 0.0089 15.6 3.1 0.026 14.1 2.1 1.8 1 0 0 1 1 1 1 IncA protein Zw10 PF06248.8 CDO69140.1 - 0.012 13.7 3.5 0.24 9.5 1.1 2.2 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 SAYSvFN PF10260.4 CDO69140.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) Baculo_PEP_C PF04513.7 CDO69140.1 - 0.076 12.8 0.3 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GrpE PF01025.14 CDO69140.1 - 0.16 11.5 1.5 0.47 9.9 1.0 1.8 1 0 0 1 1 1 0 GrpE Glutaredoxin PF00462.19 CDO69141.1 - 3.6e-14 52.5 0.0 9.1e-14 51.1 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 CDO69141.1 - 0.00018 21.6 0.0 0.00053 20.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO69141.1 - 0.014 15.3 0.0 0.064 13.2 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Cupin_2 PF07883.6 CDO69142.1 - 4.5e-14 51.6 0.2 6.9e-14 51.0 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 CDO69142.1 - 1.2e-05 24.5 0.1 3.7e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.17 CDO69142.1 - 6.7e-05 22.3 0.0 8.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 CDO69142.1 - 0.0023 17.5 0.0 0.0026 17.4 0.0 1.1 1 0 0 1 1 1 1 Cupin ARD PF03079.9 CDO69142.1 - 0.0067 16.3 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 ARD/ARD' family AraC_binding PF02311.14 CDO69142.1 - 0.023 14.3 0.1 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain MannoseP_isomer PF01050.13 CDO69142.1 - 0.043 13.4 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase GPI PF06560.6 CDO69142.1 - 0.05 12.6 0.0 0.1 11.6 0.0 1.5 1 1 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) JmjC PF02373.17 CDO69142.1 - 0.05 13.8 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase Peptidase_S8 PF00082.17 CDO69143.1 - 1.9e-44 151.9 0.5 3.1e-44 151.2 0.3 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 CDO69143.1 - 1.2e-09 37.8 0.0 2.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 CDO69143.1 - 4.9e-08 33.3 0.1 1.2e-07 32.1 0.1 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Exo_endo_phos PF03372.18 CDO69144.1 - 2e-26 93.4 0.0 2.8e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CDO69144.1 - 6e-20 70.4 8.3 3.5e-10 39.2 0.9 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO69144.1 - 1.4e-12 47.1 3.5 1.6e-10 40.5 2.0 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CDO69144.1 - 4.8e-12 44.1 2.0 0.018 14.9 0.0 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CDO69144.1 - 4.6e-09 35.0 4.3 0.034 14.3 0.1 4.8 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 CDO69144.1 - 0.00075 19.3 2.3 5.5 7.3 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich repeat GHMP_kinases_N PF00288.21 CDO69145.1 - 3.8e-09 36.4 3.1 7.3e-09 35.5 2.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Voltage_CLC PF00654.15 CDO69146.1 - 1.5e-92 310.3 31.3 2e-92 309.9 21.7 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 CDO69146.1 - 1.8e-12 46.8 0.8 1.3e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 CBS domain Phage_Coat_Gp8 PF05371.7 CDO69146.1 - 0.096 12.2 0.7 15 5.2 0.1 3.4 3 0 0 3 3 3 0 Phage major coat protein, Gp8 PriCT_2 PF08707.6 CDO69146.1 - 0.35 10.7 3.5 1.2 9.0 2.4 1.9 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) UBN2_2 PF14227.1 CDO69147.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO69147.1 - 0.19 11.6 4.5 0.34 10.9 3.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDO69147.1 - 0.3 10.7 3.3 0.52 10.0 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 CDO69148.1 - 3.5e-07 29.6 0.0 4.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69148.1 - 0.095 11.7 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Arf PF00025.16 CDO69149.1 - 9.6e-37 125.8 0.0 2.4e-36 124.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CDO69149.1 - 1.6e-10 40.2 0.2 1.1e-05 24.3 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CDO69149.1 - 4.9e-10 39.9 0.0 7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CDO69149.1 - 5.8e-07 29.0 0.0 1.1e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 CDO69149.1 - 2.4e-05 23.6 0.0 4.5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CDO69149.1 - 4.1e-05 22.8 0.0 4.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDO69149.1 - 4.8e-05 22.8 0.0 0.01 15.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDO69149.1 - 5.7e-05 23.0 0.0 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CDO69149.1 - 0.00011 22.5 0.0 0.00058 20.1 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 CDO69149.1 - 0.0008 19.5 0.0 0.002 18.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CDO69149.1 - 0.00086 18.7 0.0 0.11 11.9 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 CDO69149.1 - 0.0073 16.6 0.1 0.0097 16.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CDO69149.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 CDO69149.1 - 0.015 14.6 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase NACHT PF05729.7 CDO69149.1 - 0.019 14.6 0.1 0.092 12.4 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 CDO69149.1 - 0.024 14.6 0.1 0.087 12.8 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 CDO69149.1 - 0.028 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CDO69149.1 - 0.028 14.1 0.2 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 CDO69149.1 - 0.031 13.2 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_33 PF13671.1 CDO69149.1 - 0.033 14.0 0.1 0.16 11.8 0.0 2.1 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 CDO69149.1 - 0.037 14.8 2.5 0.13 13.0 1.7 2.1 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 CDO69149.1 - 0.04 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 CDO69149.1 - 0.059 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CDO69149.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_15 PF13175.1 CDO69149.1 - 0.1 11.6 0.1 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 CDO69149.1 - 0.12 12.3 0.1 0.2 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CDO69149.1 - 0.13 11.9 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CDO69149.1 - 0.43 10.8 2.0 0.73 10.1 1.4 1.8 1 1 0 1 1 1 0 AAA domain ATP-synt_C PF00137.16 CDO69150.1 - 1.8e-27 94.9 32.2 1.8e-16 59.7 6.6 2.7 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 CDO69150.1 - 0.017 15.3 1.1 0.99 9.6 0.3 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 Cation_efflux PF01545.16 CDO69150.1 - 1.1 8.2 10.3 0.072 12.1 1.6 2.5 1 1 0 2 2 2 0 Cation efflux family Oxidored_q2 PF00420.19 CDO69150.1 - 7.7 6.1 8.7 1.7 8.3 1.7 2.8 1 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L GPI-anchored PF10342.4 CDO69151.1 - 1.3e-06 28.8 0.1 2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CDO69151.1 - 0.037 13.5 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3304 PF11745.3 CDO69151.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3304) Asp PF00026.18 CDO69152.1 - 2.5e-74 250.4 10.1 1.9e-62 211.3 6.2 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO69152.1 - 7.4e-11 42.2 0.8 1.3e-10 41.5 0.5 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO69152.1 - 8.1e-05 23.0 0.4 0.01 16.3 0.1 3.2 2 1 0 2 2 2 1 Aspartyl protease DUF4480 PF13715.1 CDO69152.1 - 0.048 13.7 0.7 14 5.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4480) CUE PF02845.11 CDO69153.1 - 2.5e-09 36.4 0.1 4.3e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 CUE domain DUF3844 PF12955.2 CDO69154.1 - 4.6e-31 106.9 4.3 6.6e-31 106.4 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) LZ_Tnp_IS66 PF13007.2 CDO69154.1 - 0.036 14.7 1.0 0.1 13.2 0.7 1.7 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain EGF_2 PF07974.8 CDO69154.1 - 4.6 7.4 8.6 11 6.3 6.0 1.6 1 1 0 1 1 1 0 EGF-like domain Nucleoporin_FG PF13634.1 CDO69155.1 - 0.0076 16.4 7.4 0.014 15.5 5.1 1.4 1 0 0 1 1 1 1 Nucleoporin FG repeat region Bcr-Abl_Oligo PF09036.5 CDO69155.1 - 0.046 13.6 0.9 0.07 13.0 0.6 1.3 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DinB PF05163.7 CDO69155.1 - 0.11 12.1 1.1 0.15 11.7 0.8 1.2 1 0 0 1 1 1 0 DinB family FAA_hydrolase_N PF09298.6 CDO69155.1 - 0.25 11.3 2.4 0.37 10.8 1.6 1.2 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Muted PF14942.1 CDO69155.1 - 0.38 10.6 3.4 0.54 10.1 2.4 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Herpes_UL25 PF01499.11 CDO69155.1 - 1 7.6 5.1 1.3 7.2 3.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Macoilin PF09726.4 CDO69155.1 - 1.1 7.5 5.8 1.4 7.1 4.0 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF2058 PF09831.4 CDO69155.1 - 2.6 7.9 9.5 3.5 7.4 6.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) TFIIA PF03153.8 CDO69156.1 - 5.2e-57 194.4 0.8 1.8e-36 126.8 0.4 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDO69156.1 - 4.5 5.3 24.7 7.2 4.7 17.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LIN37 PF15306.1 CDO69156.1 - 8.2 6.4 8.2 0.11 12.4 0.3 1.9 2 0 0 2 2 2 0 LIN37 DUF1049 PF06305.6 CDO69157.1 - 0.11 11.9 0.1 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Gti1_Pac2 PF09729.4 CDO69158.1 - 6.2e-22 78.2 0.5 1.7e-20 73.5 0.2 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.4 CDO69159.1 - 6.3e-13 48.9 0.2 2.5e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 Gti1/Pac2 family F-box-like PF12937.2 CDO69160.1 - 7.4e-06 25.5 1.6 1.4e-05 24.7 0.0 2.4 2 1 0 2 2 2 1 F-box-like DEK_C PF08766.6 CDO69161.1 - 0.036 13.8 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 DEK C terminal domain Rubis-subs-bind PF09273.6 CDO69162.1 - 2e-13 50.3 0.1 3.6e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 CDO69162.1 - 2.4e-08 34.4 0.0 4.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 SET domain NOA36 PF06524.7 CDO69162.1 - 3.8 6.6 6.1 6.3 5.9 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein TPR_11 PF13414.1 CDO69163.1 - 3.5e-31 106.6 33.4 2.8e-07 30.0 0.0 11.0 8 3 6 14 14 14 9 TPR repeat TPR_19 PF14559.1 CDO69163.1 - 2.1e-29 101.6 25.3 6.9e-05 23.1 0.0 10.3 8 2 2 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 CDO69163.1 - 1.6e-26 90.7 25.0 7.5e-05 22.1 0.0 12.9 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_2 PF07719.12 CDO69163.1 - 5.2e-23 79.0 44.6 0.00051 19.7 0.1 14.5 16 1 1 17 17 15 6 Tetratricopeptide repeat TPR_12 PF13424.1 CDO69163.1 - 4.2e-21 74.6 35.4 8e-08 32.1 1.6 10.0 9 2 3 12 12 11 6 Tetratricopeptide repeat TPR_14 PF13428.1 CDO69163.1 - 4.2e-21 73.5 46.4 0.00079 19.8 0.2 14.8 11 4 5 16 16 13 7 Tetratricopeptide repeat TPR_16 PF13432.1 CDO69163.1 - 3e-17 62.7 53.1 0.00019 22.0 0.0 11.1 9 3 1 11 11 10 6 Tetratricopeptide repeat TPR_6 PF13174.1 CDO69163.1 - 1.8e-15 56.2 24.8 1.5e-05 25.1 0.2 12.3 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_8 PF13181.1 CDO69163.1 - 1.2e-13 49.7 12.8 0.0015 18.1 0.3 9.4 11 0 0 11 11 10 3 Tetratricopeptide repeat Apc3 PF12895.2 CDO69163.1 - 6.5e-11 42.2 15.4 0.027 14.6 0.2 7.0 5 1 1 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CDO69163.1 - 8.8e-09 34.8 20.6 4.2 7.8 0.0 11.8 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_4 PF07721.9 CDO69163.1 - 7.8e-06 25.8 8.0 4 8.1 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO69163.1 - 7.8e-05 22.1 32.3 0.23 11.3 0.0 9.7 11 2 1 12 12 10 3 Tetratricopeptide repeat TPR_10 PF13374.1 CDO69163.1 - 0.16 11.9 29.1 2.8 7.9 0.2 9.0 8 0 0 8 8 7 0 Tetratricopeptide repeat SWIRM PF04433.12 CDO69164.1 - 5e-16 58.6 0.0 1.2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain PALP PF00291.20 CDO69165.1 - 8.3e-46 156.6 0.0 8.3e-45 153.3 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_7 PF13241.1 CDO69165.1 - 0.036 14.3 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GHMP_kinases_C PF08544.8 CDO69165.1 - 0.1 12.8 0.2 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal CoA_binding_2 PF13380.1 CDO69166.1 - 2.7e-16 59.7 0.0 3.3e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain DUF4043 PF13252.1 CDO69167.1 - 0.15 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) Asp PF00026.18 CDO69168.1 - 3e-66 223.8 0.5 4e-66 223.4 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO69168.1 - 2.4e-10 40.5 0.5 2.4e-10 40.5 0.3 2.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO69168.1 - 0.00088 19.7 1.8 0.0071 16.8 0.3 3.0 2 1 1 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 CDO69168.1 - 0.14 11.6 0.2 3.5 7.1 0.2 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal EIF_2_alpha PF07541.7 CDO69169.1 - 1.8e-33 114.6 0.0 5.2e-33 113.1 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CDO69169.1 - 6.3e-13 48.6 0.8 1.1e-12 47.8 0.5 1.4 1 0 0 1 1 1 1 S1 RNA binding domain BUD22 PF09073.5 CDO69169.1 - 0.0097 15.0 0.8 0.0097 15.0 0.6 1.9 2 0 0 2 2 2 1 BUD22 Mito_carr PF00153.22 CDO69170.1 - 2.8e-64 212.8 3.8 5.5e-22 77.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NUDIX PF00293.23 CDO69171.1 - 9.4e-16 57.6 0.0 1.7e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 CDO69171.1 - 1e-13 51.3 0.1 2.3e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain MAGE_N PF12440.3 CDO69171.1 - 0.0096 16.1 1.1 0.0096 16.1 0.7 2.1 2 0 0 2 2 2 1 Melanoma associated antigen family N terminal HrpF PF06266.7 CDO69171.1 - 3.2 7.9 4.7 3.5 7.8 0.1 2.4 2 0 0 2 2 2 0 HrpF protein NUDIX PF00293.23 CDO69173.1 - 6.8e-19 67.8 0.1 1.2e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 CDO69173.1 - 3.7e-10 40.0 0.1 9.4e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 CDO69173.1 - 9.7e-05 21.7 0.1 0.00029 20.2 0.1 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 CDO69173.1 - 0.026 13.7 0.3 0.061 12.5 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain GFA PF04828.9 CDO69173.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DNA_ligase_ZBD PF03119.11 CDO69173.1 - 0.14 11.9 0.8 0.31 10.7 0.6 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_2 PF13240.1 CDO69173.1 - 0.14 11.7 0.5 0.24 10.9 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.1 CDO69173.1 - 0.34 10.6 1.5 0.37 10.5 0.2 1.7 2 0 0 2 2 2 0 Nudix N-terminal AA_permease PF00324.16 CDO69174.1 - 0.21 9.8 1.4 7.4 4.7 0.4 2.0 2 0 0 2 2 2 0 Amino acid permease CRAL_TRIO PF00650.15 CDO69175.1 - 1.1e-14 54.2 0.0 1.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CDO69175.1 - 0.0067 16.3 0.0 0.018 14.9 0.0 1.6 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Metallophos PF00149.23 CDO69176.1 - 1.5e-30 106.0 0.6 3.9e-30 104.7 0.4 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C2H2 PF00096.21 CDO69177.1 - 0.0079 16.4 8.5 0.0079 16.4 5.9 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO69177.1 - 5.8 7.3 19.1 0.22 11.8 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-CCCH PF00642.19 CDO69178.1 - 3.8e-09 36.0 2.5 9.4e-09 34.7 1.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 CDO69178.1 - 3.7e-08 32.9 5.4 6.2e-08 32.1 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO69178.1 - 8.7e-08 32.0 10.2 1.5e-07 31.3 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO69178.1 - 2.7e-07 30.1 7.6 4.6e-07 29.4 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CDO69178.1 - 2.5e-06 27.0 8.6 4.8e-06 26.1 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO69178.1 - 1.2e-05 24.9 7.0 2e-05 24.2 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CDO69178.1 - 0.0003 20.4 2.8 0.00073 19.1 2.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CDO69178.1 - 0.0054 16.5 7.6 0.013 15.3 5.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 CDO69178.1 - 0.089 12.3 1.7 0.17 11.4 1.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L34e PF01199.13 CDO69178.1 - 0.14 12.4 2.0 0.17 12.1 0.2 1.9 2 0 0 2 2 2 0 Ribosomal protein L34e zf-rbx1 PF12678.2 CDO69178.1 - 0.93 9.6 5.0 3.5 7.7 3.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger bZIP_2 PF07716.10 CDO69179.1 - 2.1e-09 37.0 13.9 4.3e-09 36.0 9.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 CDO69179.1 - 4.4e-07 29.7 7.9 9.5e-07 28.6 5.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 CDO69179.1 - 0.006 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Haemolysin XhlA MAD PF05557.8 CDO69179.1 - 0.019 13.1 0.4 0.026 12.6 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Shugoshin_N PF07558.6 CDO69179.1 - 0.046 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_Maf PF03131.12 CDO69179.1 - 0.092 13.0 4.4 0.32 11.3 2.9 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor NTP_transferase PF00483.18 CDO69180.1 - 6.8e-43 146.7 0.0 1.1e-42 146.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CDO69180.1 - 1.5e-06 28.4 0.2 3.4e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 CDO69180.1 - 0.00023 20.7 0.1 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.14 CDO69180.1 - 0.088 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF904 PF06005.7 CDO69180.1 - 0.13 12.6 0.5 0.24 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Gti1_Pac2 PF09729.4 CDO69181.1 - 1.5e-18 67.2 0.2 1.1e-15 57.8 0.0 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family GLTP PF08718.6 CDO69182.1 - 5.3e-31 107.6 0.0 8.9e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Streptin-Immun PF11083.3 CDO69182.1 - 0.1 12.5 0.2 1.3 9.0 0.0 2.3 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein GAF PF01590.21 CDO69183.1 - 0.0007 19.7 0.1 0.00094 19.3 0.1 1.2 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 CDO69183.1 - 0.0035 17.8 0.0 0.0057 17.1 0.0 1.3 1 0 0 1 1 1 1 GAF domain tRNA-synt_1e PF01406.14 CDO69184.1 - 2.2e-126 421.0 0.1 2.2e-126 421.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CDO69184.1 - 7.7e-08 31.3 1.0 2e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CDO69184.1 - 1.2e-06 26.8 0.0 2.7e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 CDO69184.1 - 7.6e-06 26.0 1.0 2e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 DALR domain DUF904 PF06005.7 CDO69186.1 - 0.011 16.0 5.6 0.011 16.0 3.9 9.4 4 3 4 8 8 8 0 Protein of unknown function (DUF904) IncA PF04156.9 CDO69186.1 - 0.012 15.2 115.7 0.018 14.6 12.5 6.8 1 1 3 6 6 6 0 IncA protein SlyX PF04102.7 CDO69186.1 - 0.034 14.5 0.8 0.034 14.5 0.6 10.6 6 3 2 9 9 9 0 SlyX Reo_sigmaC PF04582.7 CDO69186.1 - 0.11 11.7 31.1 0.053 12.6 0.4 5.3 4 3 1 5 5 5 0 Reovirus sigma C capsid protein Filament PF00038.16 CDO69186.1 - 4.6 6.6 100.7 0.058 12.8 5.1 7.3 3 1 3 6 6 6 0 Intermediate filament protein TMF_DNA_bd PF12329.3 CDO69186.1 - 6 6.7 112.0 0.18 11.6 7.4 10.5 7 2 3 10 10 10 0 TATA element modulatory factor 1 DNA binding CAP_GLY PF01302.20 CDO69187.1 - 1e-09 37.9 1.1 1.5e-09 37.3 0.8 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF566 PF04484.7 CDO69187.1 - 5.5 6.4 13.5 6.8 6.0 9.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ribosomal_L34 PF00468.12 CDO69188.1 - 1e-17 63.5 9.3 1.5e-17 62.9 6.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 CLASP_N PF12348.3 CDO69189.1 - 3.2e-28 98.6 0.0 4.6e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal Pro_racemase PF05544.6 CDO69190.1 - 5.7e-28 97.6 0.0 9.7e-28 96.9 0.0 1.4 1 1 0 1 1 1 1 Proline racemase Exo_endo_phos PF03372.18 CDO69191.1 - 6.3e-10 39.3 0.9 1.8e-09 37.8 0.6 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 CDO69191.1 - 2e-07 30.6 0.0 5.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Globin PF00042.17 CDO69191.1 - 0.11 12.9 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 Globin eIF-3c_N PF05470.7 CDO69193.1 - 3.6e-182 606.6 25.9 3.6e-182 606.6 18.0 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CDO69193.1 - 1.1e-15 57.8 0.2 3.1e-14 53.1 0.0 2.9 3 0 0 3 3 3 1 PCI domain Hexapep PF00132.19 CDO69194.1 - 3.8e-08 32.4 0.2 0.015 14.7 0.0 3.6 2 1 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CDO69194.1 - 0.015 14.8 3.2 0.025 14.1 1.5 1.9 1 1 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.20 CDO69195.1 - 2.3e-69 233.4 0.0 3.1e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69195.1 - 6.2e-50 169.6 0.0 8.8e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO69195.1 - 1.4e-07 30.8 0.0 2.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO69195.1 - 0.0015 18.2 0.0 0.23 11.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CDO69195.1 - 0.032 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 CDO69195.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APS_kinase PF01583.15 CDO69196.1 - 5.4e-62 208.0 0.5 1.3e-26 93.1 0.0 3.1 2 1 1 3 3 3 3 Adenylylsulphate kinase AAA_33 PF13671.1 CDO69196.1 - 1.3e-06 28.3 0.0 4.6e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDO69196.1 - 4.6e-05 24.2 0.0 7.6e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDO69196.1 - 0.00078 19.7 0.0 0.0021 18.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 CDO69196.1 - 0.02 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 CDO69196.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_C15 PF01470.12 CDO69197.1 - 2.4e-08 34.0 0.0 0.0073 16.1 0.0 3.2 3 1 1 4 4 4 2 Pyroglutamyl peptidase MgsA_C PF12002.3 CDO69198.1 - 2.9e-53 180.0 0.0 4.8e-53 179.2 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 CDO69198.1 - 1.6e-16 60.1 0.0 5.8e-16 58.2 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CDO69198.1 - 2e-15 57.1 0.0 6.3e-15 55.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDO69198.1 - 3.5e-08 33.2 0.0 3.4e-07 30.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CDO69198.1 - 3.7e-06 27.7 0.1 1.4e-05 25.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CDO69198.1 - 4.8e-06 26.6 2.0 0.0011 19.0 0.0 3.0 1 1 2 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 CDO69198.1 - 7.5e-06 25.8 0.0 2e-05 24.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CDO69198.1 - 9e-06 25.8 0.2 0.0011 19.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 CDO69198.1 - 1.6e-05 24.4 0.0 0.002 17.6 0.0 2.3 1 1 1 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CDO69198.1 - 1.6e-05 24.1 0.1 0.024 13.7 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 CDO69198.1 - 2.1e-05 24.1 0.1 1.1 8.5 0.0 3.7 2 1 1 3 3 3 1 AAA-like domain AAA_18 PF13238.1 CDO69198.1 - 2.6e-05 24.5 0.0 4.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CDO69198.1 - 4.1e-05 23.6 0.0 9.2e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.1 CDO69198.1 - 0.00013 21.9 0.0 0.00045 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CDO69198.1 - 0.00087 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CDO69198.1 - 0.0029 17.7 0.0 0.0092 16.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase DNA_pol3_delta2 PF13177.1 CDO69198.1 - 0.0087 15.7 0.0 0.85 9.2 0.0 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_2 PF07724.9 CDO69198.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.12 CDO69198.1 - 0.017 13.9 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 CDO69198.1 - 0.018 15.3 0.0 0.055 13.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.10 CDO69198.1 - 0.023 13.4 0.0 0.056 12.1 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 CDO69198.1 - 0.031 13.9 0.1 1.7 8.2 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase ResIII PF04851.10 CDO69198.1 - 0.034 13.9 0.1 3.5 7.4 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.17 CDO69198.1 - 0.043 13.6 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase Viral_helicase1 PF01443.13 CDO69198.1 - 0.05 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CDO69198.1 - 0.063 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 CDO69198.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 CDO69198.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 CDO69198.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CDO69198.1 - 0.17 11.0 0.0 0.39 9.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 CDO69198.1 - 0.26 10.0 0.0 1.2 7.8 0.0 1.8 1 1 1 2 2 2 0 NB-ARC domain Pre-SET PF05033.11 CDO69199.1 - 1.6e-20 73.2 3.2 1.6e-20 73.2 2.2 1.8 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.23 CDO69199.1 - 2.5e-18 66.9 1.6 2.5e-18 66.9 1.1 2.3 2 1 0 2 2 2 1 SET domain Glyco_hydro_61 PF03443.9 CDO69200.1 - 1.1e-60 205.1 1.4 1.3e-60 204.9 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1168 PF06658.7 CDO69201.1 - 9.2e-40 135.4 22.7 1.6e-39 134.6 15.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) TFIIA PF03153.8 CDO69201.1 - 0.0018 18.2 6.9 0.0025 17.7 4.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CMS1 PF14617.1 CDO69201.1 - 0.34 9.9 7.4 0.48 9.4 5.2 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit BSMAP PF12280.3 CDO69201.1 - 0.35 10.7 2.0 0.58 10.0 1.4 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein RNase_H2-Ydr279 PF09468.5 CDO69201.1 - 0.42 9.7 7.5 0.54 9.3 5.2 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ribosomal_S8e PF01201.17 CDO69202.1 - 4.7e-35 120.6 1.5 1.1e-31 109.6 0.4 2.4 2 1 0 2 2 2 2 Ribosomal protein S8e Yip1 PF04893.12 CDO69203.1 - 2.1e-08 33.8 12.1 3.3e-08 33.2 8.4 1.3 1 0 0 1 1 1 1 Yip1 domain FSA_C PF10479.4 CDO69204.1 - 0.027 12.5 0.0 0.047 11.7 0.0 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF4325 PF14213.1 CDO69205.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) DUF1746 PF08508.5 CDO69205.1 - 0.44 10.4 2.7 0.98 9.3 1.9 1.5 1 1 0 1 1 1 0 Fungal domain of unknown function (DUF1746) LPP PF04728.8 CDO69206.1 - 6.7 6.5 8.0 0.44 10.3 0.2 2.7 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Peptidase_C14 PF00656.17 CDO69207.1 - 4.7e-12 46.1 0.0 6.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Caspase domain APG6 PF04111.7 CDO69208.1 - 2.1e-116 388.3 1.5 2.6e-116 388.0 1.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 CDO69208.1 - 0.017 12.9 4.3 0.024 12.5 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 CDO69208.1 - 9.4 4.5 8.4 13 4.0 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GCS PF03074.11 CDO69209.1 - 2.3e-123 411.9 4.2 1.9e-84 283.8 0.2 3.1 1 1 2 3 3 3 3 Glutamate-cysteine ligase DUF1793 PF08760.6 CDO69210.1 - 7.5e-31 107.2 0.2 1.4e-30 106.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) SKG6 PF08693.5 CDO69210.1 - 0.16 11.3 1.2 0.43 9.9 0.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VanZ PF04892.7 CDO69211.1 - 9.1e-06 25.6 0.9 9.1e-06 25.6 0.6 2.0 1 1 1 2 2 2 1 VanZ like family DUF2339 PF10101.4 CDO69211.1 - 0.012 13.9 0.7 0.015 13.6 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Acyl_transf_3 PF01757.17 CDO69211.1 - 0.064 12.0 6.1 0.083 11.7 4.3 1.2 1 0 0 1 1 1 0 Acyltransferase family PALP PF00291.20 CDO69213.1 - 5.8e-64 216.2 0.1 7.3e-64 215.9 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.16 CDO69214.1 - 8.4e-64 214.0 0.5 8.4e-61 204.2 0.3 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CDO69214.1 - 2.9e-09 36.4 0.0 3.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CDO69214.1 - 1.6e-08 33.6 0.1 3.8e-08 32.4 0.1 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 CDO69214.1 - 1.2e-06 27.9 0.1 2.2e-06 27.0 0.0 1.4 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CDO69214.1 - 1.7e-06 27.3 0.0 2.2e-05 23.7 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CDO69214.1 - 1.2e-05 25.7 0.0 1.6e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein L27 PF02828.11 CDO69214.1 - 0.025 14.2 1.1 0.11 12.1 0.1 2.1 2 0 0 2 2 2 0 L27 domain MMR_HSR1 PF01926.18 CDO69214.1 - 0.029 14.3 0.0 0.092 12.7 0.0 1.6 1 1 1 2 2 2 0 50S ribosome-binding GTPase Macro_2 PF14519.1 CDO69215.1 - 0.058 12.4 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Macro-like domain LRR_4 PF12799.2 CDO69216.1 - 1.4e-15 56.5 13.6 2.6e-06 26.9 1.9 4.6 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO69216.1 - 1.4e-15 56.8 13.3 1.5e-11 43.8 4.3 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CDO69216.1 - 3.3e-08 32.4 15.7 0.071 13.1 0.1 6.2 5 1 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 CDO69216.1 - 0.013 15.5 11.7 13 6.4 0.1 5.2 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 CDO69216.1 - 0.35 11.0 16.8 2.5 8.4 0.5 5.0 4 2 2 6 6 6 0 Leucine Rich repeat UBA PF00627.26 CDO69217.1 - 3.3e-24 84.0 4.0 7.8e-13 47.8 0.2 2.8 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 CDO69217.1 - 2e-20 71.9 2.0 3.3e-20 71.2 1.4 1.3 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 CDO69217.1 - 5.6e-17 60.9 7.6 5.6e-17 60.9 5.3 2.2 2 0 0 2 2 1 1 XPC-binding domain Rad60-SLD PF11976.3 CDO69217.1 - 1.3e-09 37.5 1.8 3.8e-09 36.0 1.1 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CDO69217.1 - 9.2e-05 22.5 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CDO69217.1 - 0.00076 19.3 0.1 0.0019 18.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like WIYLD PF10440.4 CDO69217.1 - 0.00084 19.2 0.1 0.83 9.6 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin-binding WIYLD domain Ubiquitin_2 PF14560.1 CDO69217.1 - 0.0017 18.5 0.3 0.0031 17.7 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain UBA_3 PF09288.5 CDO69217.1 - 0.0023 17.5 0.0 0.44 10.1 0.0 2.4 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain CUE PF02845.11 CDO69217.1 - 0.013 14.9 0.0 0.1 12.0 0.0 2.4 3 0 0 3 3 3 0 CUE domain MSA-2c PF12238.3 CDO69217.1 - 0.015 14.9 8.9 0.67 9.5 0.4 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c Rap1_C PF11626.3 CDO69217.1 - 0.11 12.3 0.0 5.2 7.0 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Med3 PF11593.3 CDO69217.1 - 0.16 11.1 21.8 0.017 14.3 3.6 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal HNH_2 PF13391.1 CDO69218.1 - 1.2e-08 34.5 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease IMS PF00817.15 CDO69221.1 - 1.7e-46 157.7 0.1 6e-46 155.9 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 CDO69221.1 - 1.3e-10 41.2 0.1 3.8e-09 36.5 0.1 2.7 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CDO69221.1 - 5.7e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-U1 PF06220.7 CDO69222.1 - 3.4e-12 45.6 2.0 5.3e-12 45.0 1.4 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 CDO69222.1 - 0.76 9.9 5.1 2.6 8.2 3.5 1.9 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding UPF0020 PF01170.13 CDO69224.1 - 0.00029 20.4 0.0 0.00043 19.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 CDO69224.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 1 0 1 1 1 0 DNA methylase Met_10 PF02475.11 CDO69224.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein 2OG-FeII_Oxy_2 PF13532.1 CDO69225.1 - 1.5e-17 64.0 0.0 2.8e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3506 PF12014.3 CDO69226.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Sdh_cyt PF01127.17 CDO69227.1 - 4.4e-25 87.8 0.8 5.5e-25 87.5 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ATP-synt_DE_N PF02823.11 CDO69228.1 - 3.7e-20 71.4 0.3 8.7e-20 70.2 0.1 1.7 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Pyridox_oxidase PF01243.15 CDO69229.1 - 1.8e-11 43.8 0.1 1.5e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase HSP9_HSP12 PF04119.7 CDO69230.1 - 4.5e-19 68.2 11.9 5.9e-19 67.9 6.4 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 DUF3484 PF11983.3 CDO69230.1 - 0.075 13.8 0.4 0.26 12.1 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) Lipase_3 PF01764.20 CDO69232.1 - 2.5e-24 85.4 0.0 3.5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 CDO69232.1 - 0.0066 15.7 0.0 0.009 15.3 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 CDO69232.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO69232.1 - 0.048 13.5 0.1 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Aminotran_3 PF00202.16 CDO69233.1 - 1.3e-107 359.6 0.0 1.5e-107 359.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CDO69233.1 - 4.1e-07 29.2 0.0 5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CDO69233.1 - 0.00093 18.4 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase zf-Apc11 PF12861.2 CDO69233.1 - 0.084 12.7 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CDO69235.1 - 1.6e-13 50.2 5.9 2.6e-13 49.5 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDO69235.1 - 1.5e-07 31.4 0.8 3e-07 30.4 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CDO69235.1 - 1.1e-06 28.5 4.3 1.9e-06 27.7 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDO69235.1 - 1.9e-06 27.6 1.7 3.6e-06 26.7 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CDO69235.1 - 3.4e-06 26.5 2.9 5.9e-06 25.7 2.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CDO69235.1 - 1.5e-05 24.5 1.4 2.9e-05 23.6 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO69235.1 - 2.4e-05 23.9 2.4 3.9e-05 23.2 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CDO69235.1 - 2.6e-05 23.7 2.5 4.4e-05 23.0 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CDO69235.1 - 0.0057 16.5 2.5 0.014 15.2 1.8 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 CDO69235.1 - 0.019 14.9 3.3 0.033 14.2 2.3 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 CDO69235.1 - 0.66 9.7 3.4 1.6 8.4 0.8 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Aminotran_3 PF00202.16 CDO69237.1 - 5.1e-38 130.7 0.0 5.9e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CDO69237.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase HSP9_HSP12 PF04119.7 CDO69238.1 - 4.4e-22 77.9 8.1 4.9e-22 77.7 3.6 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 DUF4450 PF14614.1 CDO69239.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) Vitelline_membr PF10542.4 CDO69239.1 - 2.5 7.8 7.2 1 9.0 1.7 2.7 2 1 0 2 2 2 0 Vitelline membrane cysteine-rich region Aa_trans PF01490.13 CDO69241.1 - 1.6e-64 217.9 23.7 8.3e-64 215.5 16.4 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CDO69241.1 - 0.0013 17.6 10.0 0.0013 17.6 6.9 2.6 2 2 0 2 2 2 1 Tryptophan/tyrosine permease family VirD1 PF07328.6 CDO69241.1 - 0.075 12.8 0.1 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 T-DNA border endonuclease VirD1 GHMP_kinases_N PF00288.21 CDO69242.1 - 2.9e-12 46.4 1.7 9.7e-12 44.7 1.2 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CDO69242.1 - 0.0026 17.9 0.0 0.0087 16.2 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal DUF1727 PF08353.5 CDO69242.1 - 0.096 12.3 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) ABC_membrane PF00664.18 CDO69243.1 - 4.8e-84 282.0 21.6 7.6e-43 146.9 3.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CDO69243.1 - 6.2e-71 237.0 0.0 3.4e-34 118.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CDO69243.1 - 5e-15 55.3 0.7 8.3e-05 21.9 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDO69243.1 - 1.1e-12 48.5 0.0 0.02 14.8 0.0 4.2 4 0 0 4 4 4 4 AAA domain ABC_ATPase PF09818.4 CDO69243.1 - 1.5e-09 36.9 0.5 0.00038 19.1 0.1 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 CDO69243.1 - 4.7e-08 32.4 1.0 0.00084 18.8 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CDO69243.1 - 1.7e-07 31.4 2.9 0.00069 19.6 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CDO69243.1 - 5e-07 30.5 0.1 0.046 14.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 CDO69243.1 - 8.3e-06 25.0 0.0 0.057 12.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CDO69243.1 - 6e-05 23.1 3.4 0.23 11.5 0.2 3.9 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CDO69243.1 - 6.3e-05 22.6 0.6 0.3 10.6 0.1 3.4 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.15 CDO69243.1 - 0.00026 19.8 0.0 0.052 12.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.7 CDO69243.1 - 0.00036 19.6 0.0 0.29 10.1 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 CDO69243.1 - 0.0004 20.2 0.3 1.1 9.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CDO69243.1 - 0.00045 20.0 2.9 0.95 9.4 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 CDO69243.1 - 0.0013 19.0 0.0 2.1 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CDO69243.1 - 0.0014 18.3 0.1 1.3 8.7 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CDO69243.1 - 0.0015 18.7 1.1 0.51 10.5 0.0 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 CDO69243.1 - 0.0018 17.3 0.0 1.5 7.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 CDO69243.1 - 0.0021 17.5 3.4 0.6 9.4 0.0 3.2 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CDO69243.1 - 0.0026 18.0 0.0 0.75 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CDO69243.1 - 0.0035 17.3 1.2 0.92 9.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 CDO69243.1 - 0.01 15.5 0.3 5.2 6.7 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 CDO69243.1 - 0.012 15.1 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.20 CDO69243.1 - 0.016 14.6 0.0 7.5 5.9 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 CDO69243.1 - 0.021 14.7 0.0 4.4 7.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.18 CDO69243.1 - 0.022 14.7 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 CDO69243.1 - 0.042 13.3 0.1 5.9 6.3 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CDO69243.1 - 0.065 13.4 0.0 5.9 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 CDO69243.1 - 0.075 12.6 0.0 15 5.1 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.8 CDO69243.1 - 0.075 11.9 0.0 3.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 CDO69243.1 - 0.17 10.6 0.0 7.6 5.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 CDO69243.1 - 0.19 11.1 3.6 11 5.2 0.1 3.8 5 0 0 5 5 4 0 AAA-like domain DUF87 PF01935.12 CDO69243.1 - 0.32 10.7 1.5 7.7 6.2 0.1 2.9 3 0 0 3 3 2 0 Domain of unknown function DUF87 Rsd_AlgQ PF04353.8 CDO69244.1 - 0.048 13.3 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DAP3 PF10236.4 CDO69245.1 - 0.03 13.2 0.1 4.1 6.2 0.0 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 UDPGT PF00201.13 CDO69247.1 - 4.9e-16 58.3 0.1 7.3e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CDO69247.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF1080 PF06439.6 CDO69248.1 - 0.037 13.9 0.0 0.049 13.5 0.0 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) Pro-kuma_activ PF09286.6 CDO69249.1 - 3.9e-40 137.1 0.0 5.9e-39 133.3 0.0 2.3 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO69249.1 - 1.7e-09 37.2 2.0 2.3e-09 36.7 1.4 1.2 1 0 0 1 1 1 1 Subtilase family Lipase_3 PF01764.20 CDO69250.1 - 2.2e-27 95.3 0.1 3.1e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CDO69250.1 - 0.0016 17.8 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) DUF676 PF05057.9 CDO69250.1 - 0.0025 17.1 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.17 CDO69250.1 - 0.0041 16.8 0.1 0.007 16.1 0.1 1.5 1 1 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 CDO69250.1 - 0.039 13.8 0.4 0.16 11.8 0.1 1.7 1 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO69250.1 - 0.057 12.9 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 CDO69250.1 - 0.057 12.9 0.1 0.41 10.1 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF21 PF01595.15 CDO69251.1 - 4.6e-24 84.7 1.0 7.1e-24 84.1 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 Pkinase PF00069.20 CDO69253.1 - 1.2e-59 201.5 0.0 1.5e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69253.1 - 6.4e-30 104.0 0.0 8.9e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO69253.1 - 1.4e-08 34.0 0.0 2.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO69253.1 - 0.013 15.2 0.4 0.14 11.8 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CDO69253.1 - 0.04 12.9 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.24 CDO69253.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 PH domain ACT PF01842.20 CDO69254.1 - 3.9e-12 45.3 0.0 6.1e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 CDO69254.1 - 2.7e-08 33.5 0.1 4.2e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 ACT domain COG5 PF10392.4 CDO69255.1 - 2.3e-23 82.5 0.0 1.8e-22 79.7 0.0 2.4 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG2 PF06148.6 CDO69255.1 - 0.44 10.4 2.1 6.8 6.5 0.1 3.5 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4106 PF13388.1 CDO69257.1 - 2.2 7.1 5.0 3 6.7 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Zn_clus PF00172.13 CDO69258.1 - 1.2e-05 25.0 9.1 2.4e-05 24.1 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPT PF03151.11 CDO69259.1 - 3.2e-31 108.0 7.5 3.2e-31 108.0 5.2 2.4 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 CDO69259.1 - 6.3e-07 28.6 19.2 1.1e-06 27.8 13.3 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CDO69259.1 - 8.9e-07 28.9 29.3 0.00084 19.3 6.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family Peptidase_C12 PF01088.16 CDO69260.1 - 3.4e-56 189.8 0.0 5.3e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF1018 PF06252.7 CDO69260.1 - 0.045 14.2 1.2 0.073 13.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) AA_permease PF00324.16 CDO69261.1 - 4.7e-109 364.8 45.6 5.8e-109 364.5 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CDO69261.1 - 1.1e-32 113.1 51.6 1.4e-32 112.7 35.7 1.1 1 0 0 1 1 1 1 Amino acid permease Vac7 PF12751.2 CDO69262.1 - 0.032 13.0 0.6 0.043 12.6 0.4 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 IFP_35_N PF07334.8 CDO69262.1 - 0.075 13.0 0.7 0.15 12.0 0.5 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Adeno_PIX PF03955.9 CDO69262.1 - 0.95 10.0 6.6 0.14 12.6 1.7 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) FAD_binding_2 PF00890.19 CDO69263.1 - 7.3e-92 308.3 0.1 9.7e-92 307.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 CDO69263.1 - 8.4e-25 86.3 0.0 1.9e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 CDO69263.1 - 3.8e-12 45.8 0.1 6.4e-10 38.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CDO69263.1 - 2.9e-11 43.6 0.1 6.1e-09 36.0 0.1 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO69263.1 - 2.1e-10 40.4 0.1 1.6e-09 37.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CDO69263.1 - 1.8e-08 33.8 0.0 2.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CDO69263.1 - 2e-06 28.0 0.2 6.3e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CDO69263.1 - 2.1e-06 27.0 0.8 4e-06 26.1 0.5 1.5 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CDO69263.1 - 2.2e-06 26.8 1.3 6.7e-05 21.9 0.3 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 CDO69263.1 - 3.2e-06 25.8 3.2 5.3e-05 21.8 0.2 2.9 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 CDO69263.1 - 1.3e-05 24.3 0.9 0.0042 16.1 0.3 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.1 CDO69263.1 - 8.5e-05 22.3 0.1 0.001 18.8 0.0 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 CDO69263.1 - 0.00096 18.3 0.0 0.0051 15.9 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 CDO69263.1 - 0.0012 17.8 0.2 0.0064 15.4 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 CDO69263.1 - 0.0057 17.0 0.4 0.023 15.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 CDO69263.1 - 0.014 15.6 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 CDO69263.1 - 0.02 14.4 0.3 0.04 13.4 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CDO69263.1 - 0.044 13.4 0.2 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rnk_N PF14760.1 CDO69263.1 - 0.076 13.0 0.1 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 Rnk N-terminus Pro-kuma_activ PF09286.6 CDO69264.1 - 1.3e-37 129.0 0.1 3.3e-36 124.4 0.0 2.6 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO69264.1 - 3.6e-06 26.3 4.2 6.3e-06 25.5 2.9 1.6 1 1 0 1 1 1 1 Subtilase family Ish1 PF10281.4 CDO69264.1 - 0.095 12.7 0.1 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF4366 PF14283.1 CDO69265.1 - 0.019 14.3 3.5 0.026 13.9 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Apolipoprotein PF01442.13 CDO69265.1 - 0.024 14.1 9.4 0.033 13.6 6.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain AIF-MLS PF14962.1 CDO69265.1 - 0.14 11.8 11.9 0.43 10.1 8.0 2.1 1 1 0 1 1 1 0 Mitochondria Localisation Sequence Remorin_C PF03763.8 CDO69265.1 - 0.36 10.3 23.8 0.022 14.2 8.3 3.0 1 1 2 3 3 3 0 Remorin, C-terminal region DUF883 PF05957.8 CDO69265.1 - 1 9.8 21.8 0.31 11.4 7.1 2.9 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) His_Phos_2 PF00328.17 CDO69269.1 - 0.00071 18.9 0.5 0.024 13.9 0.3 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 CDO69271.1 - 2.6e-22 79.5 0.1 7.3e-22 78.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO69271.1 - 1.7e-06 27.8 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CDO69271.1 - 8.4e-05 21.8 0.0 0.00011 21.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 CDO69271.1 - 0.00034 20.1 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO69271.1 - 0.0017 18.3 0.1 0.003 17.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 CDO69271.1 - 0.0021 17.8 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 CDO69271.1 - 0.0053 16.5 4.6 0.011 15.5 3.1 1.7 1 1 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1762 PF08574.5 CDO69272.1 - 2.7e-12 46.9 7.8 2.7e-12 46.9 5.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) Flexi_CP PF00286.15 CDO69272.1 - 0.021 14.5 0.1 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 Viral coat protein TFIIA PF03153.8 CDO69272.1 - 0.029 14.2 14.0 0.051 13.4 9.7 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3138 PF11336.3 CDO69272.1 - 1.9 6.5 4.6 2.7 6.0 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) F-box-like PF12937.2 CDO69274.1 - 5.8e-14 51.5 0.5 3.2e-13 49.1 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDO69274.1 - 0.03 13.9 4.1 0.43 10.2 1.3 3.6 2 1 0 2 2 2 0 F-box domain Fungal_trans PF04082.13 CDO69276.1 - 0.034 13.0 0.8 0.14 11.0 0.0 2.2 2 1 1 3 3 3 0 Fungal specific transcription factor domain MFS_1 PF07690.11 CDO69278.1 - 4.9e-30 104.4 17.7 1.7e-18 66.4 2.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PHY PF00360.15 CDO69279.1 - 4.4e-23 81.3 0.0 8e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 CDO69279.1 - 2.3e-21 75.5 0.0 4.6e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CDO69279.1 - 9.5e-19 67.4 0.1 3.7e-18 65.5 0.0 2.0 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 CDO69279.1 - 9.5e-12 44.7 0.8 9.5e-12 44.7 0.5 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 CDO69279.1 - 3.3e-09 37.0 0.5 1.3e-07 31.8 0.1 3.3 2 1 0 2 2 2 1 GAF domain PAS_2 PF08446.6 CDO69279.1 - 5.5e-08 33.2 0.1 6.2e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 PAS fold OKR_DC_1_N PF03709.10 CDO69279.1 - 3.9e-05 23.6 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain BTB PF00651.26 CDO69282.1 - 0.0005 20.0 0.0 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain TF_Zn_Ribbon PF08271.7 CDO69282.1 - 0.071 12.4 0.2 0.52 9.6 0.0 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 CDO69282.1 - 0.14 11.3 1.3 2.2 7.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-FCS PF06467.9 CDO69282.1 - 0.54 9.9 3.1 11 5.7 0.3 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif adh_short PF00106.20 CDO69284.1 - 1.6e-18 67.1 6.4 8.5e-18 64.8 4.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO69284.1 - 2.6e-15 56.8 2.2 4.2e-15 56.1 1.5 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO69284.1 - 0.00022 20.9 6.3 0.002 17.8 0.3 2.9 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 CDO69284.1 - 0.00025 20.5 0.6 0.0024 17.3 0.4 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CDO69284.1 - 0.0079 16.2 0.2 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 CDO69284.1 - 0.025 13.4 0.1 0.048 12.5 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CDO69284.1 - 0.081 12.9 2.2 0.16 11.9 1.5 1.8 1 1 0 1 1 1 0 NADH(P)-binding SIS PF01380.17 CDO69284.1 - 0.12 11.9 0.3 0.78 9.3 0.0 2.4 2 1 0 2 2 2 0 SIS domain Eno-Rase_NADH_b PF12242.3 CDO69284.1 - 0.13 12.0 0.8 0.36 10.6 0.6 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TFIIA PF03153.8 CDO69285.1 - 6.7 6.4 9.8 7.9 6.2 6.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDO69285.1 - 9.2 4.3 27.3 9.7 4.2 18.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ODC_AZ PF02100.12 CDO69286.1 - 3e-18 65.2 0.0 4.6e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme PIF1 PF05970.9 CDO69287.1 - 7.2e-73 245.6 0.0 9.4e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CDO69287.1 - 8.4e-08 32.0 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CDO69287.1 - 7.4e-07 28.4 0.0 5.9e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 CDO69287.1 - 0.00089 18.9 0.1 0.0057 16.3 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 CDO69287.1 - 0.004 17.2 0.0 0.0083 16.2 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CDO69287.1 - 0.024 14.1 0.6 4.4 6.7 0.1 2.9 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 CDO69287.1 - 0.034 13.8 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CDO69287.1 - 0.043 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF2791 PF10923.3 CDO69287.1 - 0.058 12.0 0.0 0.089 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) SNase PF00565.12 CDO69288.1 - 1.2e-57 192.8 0.1 9.5e-21 74.0 0.1 6.1 6 0 0 6 6 6 6 Staphylococcal nuclease homologue TUDOR PF00567.19 CDO69288.1 - 4.5e-22 78.1 0.0 9.9e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Ribosomal_S6 PF01250.12 CDO69289.1 - 9.2e-11 41.4 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 HAD_2 PF13419.1 CDO69290.1 - 5.1e-12 46.3 0.0 1.3e-11 45.0 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CDO69290.1 - 6.9e-11 41.7 0.0 1.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CDO69290.1 - 0.00024 21.6 0.0 0.0033 17.8 0.0 2.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase RRM_2 PF04059.7 CDO69291.1 - 2.8e-31 107.3 1.1 5.1e-31 106.5 0.7 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_6 PF14259.1 CDO69291.1 - 2.4e-13 49.8 0.3 8.7e-05 22.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO69291.1 - 2e-12 46.5 0.0 0.00064 19.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO69291.1 - 0.0018 18.0 0.1 0.34 10.7 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.7 CDO69291.1 - 0.035 13.6 0.1 2.7 7.6 0.0 2.8 3 0 0 3 3 3 0 BRCA1-associated protein 2 SOG2 PF10428.4 CDO69291.1 - 0.2 10.2 4.9 0.34 9.4 3.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SNF2_N PF00176.18 CDO69292.1 - 2.7e-67 226.6 0.0 4.8e-67 225.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 CDO69292.1 - 6.7e-20 71.0 0.0 1.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.13 CDO69292.1 - 4e-15 55.8 0.0 1.1e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.26 CDO69292.1 - 1.1e-08 34.8 0.0 0.00025 20.8 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CDO69292.1 - 1.4e-08 34.3 4.3 2.8e-08 33.4 3.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDO69292.1 - 1.6e-08 34.4 5.8 3e-08 33.5 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO69292.1 - 1.9e-07 30.5 4.7 3.7e-07 29.6 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO69292.1 - 1.2e-06 28.0 6.5 2.1e-06 27.3 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO69292.1 - 1.6e-06 27.7 3.2 2.9e-06 26.9 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 CDO69292.1 - 2.2e-05 24.3 0.0 5.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.1 CDO69292.1 - 3.2e-05 23.7 6.9 6.4e-05 22.7 4.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CDO69292.1 - 0.00073 19.5 1.4 0.0017 18.4 1.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CDO69292.1 - 0.032 13.9 7.9 0.018 14.7 3.7 2.0 2 0 0 2 2 2 0 RING-type zinc-finger WW PF00397.21 CDO69292.1 - 0.039 13.8 0.4 0.092 12.6 0.3 1.6 1 0 0 1 1 1 0 WW domain DUF760 PF05542.6 CDO69292.1 - 0.11 12.7 0.2 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF760) zf-RING_6 PF14835.1 CDO69292.1 - 0.37 10.6 3.7 0.85 9.4 2.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Metallophos PF00149.23 CDO69293.1 - 0.00012 21.5 0.0 0.001 18.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ten1_2 PF15490.1 CDO69294.1 - 6.5e-07 28.9 0.0 8.5e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit UDPGP PF01704.13 CDO69295.1 - 3.6e-182 605.5 0.9 4.1e-182 605.3 0.6 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase U3_assoc_6 PF08640.6 CDO69297.1 - 2.1e-27 94.6 0.6 9.8e-26 89.3 0.3 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 CDO69297.1 - 0.0028 18.1 13.3 0.8 10.5 0.9 5.3 4 2 2 6 6 6 2 Tetratricopeptide repeat NRDE-2 PF08424.5 CDO69297.1 - 0.0063 15.4 1.0 0.3 9.9 0.2 2.8 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference FCH PF00611.18 CDO69297.1 - 0.11 12.7 0.3 5.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Pkinase PF00069.20 CDO69298.1 - 1.7e-38 132.2 0.0 3e-24 85.5 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69298.1 - 7.1e-19 67.8 0.0 1.8e-18 66.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO69298.1 - 0.079 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Cyclin PF08613.6 CDO69299.1 - 1.3e-27 97.0 0.2 2.2e-27 96.3 0.0 1.5 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CDO69299.1 - 5.7e-05 22.6 1.3 7.5e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Ribosomal_L11_N PF03946.9 CDO69300.1 - 4.1e-18 64.5 0.1 6.5e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CDO69300.1 - 4.3e-10 39.5 0.3 1.3e-09 38.0 0.2 1.9 1 1 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pab87_oct PF13969.1 CDO69300.1 - 0.072 13.1 0.0 0.23 11.5 0.0 1.9 1 1 0 1 1 1 0 Pab87 octamerisation domain tRNA-synt_1 PF00133.17 CDO69301.1 - 2.4e-223 742.5 0.3 2.6e-222 739.1 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CDO69301.1 - 1.1e-27 96.6 0.1 2.3e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CDO69301.1 - 4.3e-16 58.5 0.9 5e-06 25.4 0.3 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CDO69301.1 - 0.03 13.4 0.0 0.18 10.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-C2H2_jaz PF12171.3 CDO69302.1 - 2.3e-08 33.9 0.1 4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CDO69302.1 - 1.1e-06 28.6 0.1 1.7e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 CDO69302.1 - 1.7e-05 24.6 5.6 1.7e-05 24.6 3.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 CDO69302.1 - 0.0032 17.1 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2 PF00096.21 CDO69302.1 - 0.042 14.1 0.2 0.075 13.4 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Atg14 PF10186.4 CDO69302.1 - 0.58 9.0 14.7 1.2 7.9 2.9 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 CDO69302.1 - 1.8 8.9 9.6 0.25 11.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 CDO69302.1 - 2.6 8.5 13.1 0.77 10.2 4.0 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Bud13 PF09736.4 CDO69302.1 - 8.3 6.6 18.8 5.4 7.2 1.0 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex HATPase_c_3 PF13589.1 CDO69303.1 - 0.0019 17.8 0.1 0.0047 16.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sep15_SelM PF08806.6 CDO69303.1 - 0.026 14.2 2.7 3.6 7.3 0.0 3.9 3 2 0 3 3 3 0 Sep15/SelM redox domain HATPase_c PF02518.21 CDO69303.1 - 0.042 13.5 0.2 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M41 PF01434.13 CDO69303.1 - 0.054 12.9 9.7 2.7 7.4 0.1 3.7 4 0 0 4 4 4 0 Peptidase family M41 DUF883 PF05957.8 CDO69303.1 - 0.096 13.0 0.5 0.096 13.0 0.3 5.5 6 1 1 7 7 7 0 Bacterial protein of unknown function (DUF883) DUF1771 PF08590.5 CDO69303.1 - 0.15 12.0 0.1 0.15 12.0 0.0 4.5 3 3 1 4 4 4 0 Domain of unknown function (DUF1771) Med15_fungi PF05397.7 CDO69303.1 - 0.53 10.2 3.9 0.37 10.7 0.4 2.2 2 0 0 2 2 2 0 Mediator complex subunit 15 DUF4423 PF14394.1 CDO69303.1 - 4.5 6.7 8.6 1.3 8.5 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4423) CHASE3 PF05227.8 CDO69303.1 - 7.2 6.2 15.2 1.3 8.7 0.2 3.9 5 0 0 5 5 5 0 CHASE3 domain Transpep_BrtH PF14399.1 CDO69303.1 - 7.8 5.6 10.0 3.5 6.8 4.1 2.4 3 1 1 4 4 4 0 NlpC/p60-like transpeptidase Prominin PF05478.6 CDO69303.1 - 8.8 3.7 6.1 5.7 4.3 1.9 2.0 1 1 0 1 1 1 0 Prominin LRR_4 PF12799.2 CDO69304.1 - 0.87 9.2 6.5 0.56 9.8 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CDO69304.1 - 3.4 8.0 5.7 52 4.3 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeat BTB PF00651.26 CDO69305.1 - 0.0064 16.4 0.0 3.7 7.5 0.0 2.8 2 1 0 2 2 2 2 BTB/POZ domain DUF2392 PF10288.4 CDO69305.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) CAF1A PF12253.3 CDO69307.1 - 0.36 10.9 9.8 0.8 9.8 6.8 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 subunit A AAA PF00004.24 CDO69309.1 - 3.4e-06 27.2 0.1 9.8e-05 22.5 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CDO69309.1 - 0.042 12.5 0.3 0.2 10.2 0.0 2.2 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein AstE_AspA PF04952.9 CDO69310.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family SUR7 PF06687.7 CDO69311.1 - 0.0089 15.6 0.0 0.023 14.2 0.0 1.6 1 1 0 1 1 1 1 SUR7/PalI family Tetraspannin PF00335.15 CDO69311.1 - 0.012 14.9 2.2 6.5 5.9 0.0 2.8 3 0 0 3 3 3 0 Tetraspanin family Cid2 PF09774.4 CDO69311.1 - 0.017 15.2 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 DUF2407_C PF13373.1 CDO69311.1 - 0.017 15.0 1.1 0.033 14.0 0.0 1.8 2 0 0 2 2 2 0 DUF2407 C-terminal domain Acyl-thio_N PF12590.3 CDO69311.1 - 0.11 12.9 0.1 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-ATP thioesterase CPSase_sm_chain PF00988.17 CDO69312.1 - 1.8e-45 153.6 0.0 2.6e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CDO69312.1 - 1.1e-35 122.8 0.0 1.6e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CDO69312.1 - 5.5e-08 32.5 0.1 5.8e-07 29.1 0.0 2.4 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.19 CDO69312.1 - 0.00087 18.7 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family BSD PF03909.12 CDO69313.1 - 1.8e-08 33.9 0.0 5.4e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 BSD domain DUF883 PF05957.8 CDO69313.1 - 0.012 15.9 5.2 1.9 8.9 0.0 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF2267 PF10025.4 CDO69313.1 - 0.019 15.0 1.6 0.019 15.0 1.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) rve PF00665.21 CDO69315.1 - 6.3e-24 84.3 0.0 2.6e-22 79.1 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CDO69315.1 - 7.1e-24 84.3 0.0 1.3e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 CDO69315.1 - 0.00077 18.8 0.1 0.002 17.5 0.0 1.7 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger RVT_2 PF07727.9 CDO69315.1 - 0.2 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MAP7 PF05672.6 CDO69316.1 - 0.046 13.0 37.3 0.018 14.4 3.6 2.1 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Retrotrans_gag PF03732.12 CDO69318.1 - 1.2e-09 38.1 0.1 2.6e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO69318.1 - 0.0045 16.8 1.4 0.011 15.6 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 CDO69318.1 - 0.042 13.3 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 CDO69318.1 - 0.053 13.0 0.1 0.13 11.7 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle UBN2 PF14223.1 CDO69318.1 - 0.056 13.2 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Pirin_C PF05726.8 CDO69319.1 - 1.2e-15 57.4 0.0 1.8e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Pirin C-terminal cupin domain DUF3944 PF13099.1 CDO69319.1 - 0.045 13.2 0.1 0.097 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) Transposase_21 PF02992.9 CDO69320.1 - 3.3e-14 52.5 0.0 5.9e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Velvet PF11754.3 CDO69321.1 - 8.8e-19 67.9 0.0 1.7e-18 66.9 0.0 1.5 1 1 0 1 1 1 1 Velvet factor F-box-like PF12937.2 CDO69322.1 - 0.00085 18.9 0.1 0.0018 17.9 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO69322.1 - 0.047 13.3 0.5 0.11 12.1 0.3 1.6 1 0 0 1 1 1 0 F-box domain Metallophos PF00149.23 CDO69323.1 - 1.5e-10 40.8 0.0 2.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDO69323.1 - 1.5e-05 24.8 0.1 6.6e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Gaa1 PF04114.9 CDO69324.1 - 0.12 10.9 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component AAA_13 PF13166.1 CDO69324.1 - 0.28 9.5 2.6 0.38 9.1 1.8 1.1 1 0 0 1 1 1 0 AAA domain Nnf1 PF03980.9 CDO69325.1 - 2.6e-14 53.1 2.2 2.6e-14 53.1 1.5 1.6 1 1 1 2 2 2 1 Nnf1 NTR2 PF15458.1 CDO69325.1 - 0.0012 18.1 1.8 0.0014 17.9 1.3 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 CASP_C PF08172.7 CDO69325.1 - 0.0067 15.4 1.8 0.0086 15.1 1.2 1.2 1 0 0 1 1 1 1 CASP C terminal DUF904 PF06005.7 CDO69325.1 - 0.021 15.0 4.2 0.047 13.9 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TMF_TATA_bd PF12325.3 CDO69325.1 - 0.068 12.8 5.0 0.12 12.1 1.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 CDO69325.1 - 0.069 13.1 0.5 0.069 13.1 0.4 2.2 2 1 1 3 3 3 0 bZIP transcription factor Herpes_BLRF2 PF05812.7 CDO69325.1 - 0.073 12.8 5.2 0.086 12.6 1.8 2.0 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF1840 PF08895.6 CDO69325.1 - 0.092 12.7 1.2 0.26 11.3 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) ATP-synt_D PF01813.12 CDO69325.1 - 0.18 11.3 3.9 0.091 12.3 1.1 1.6 2 0 0 2 2 2 0 ATP synthase subunit D Mnd1 PF03962.10 CDO69325.1 - 0.34 10.5 3.8 0.48 10.0 2.5 1.3 1 1 0 1 1 1 0 Mnd1 family DivIC PF04977.10 CDO69325.1 - 0.38 10.2 6.0 0.38 10.2 2.3 2.1 2 0 0 2 2 2 0 Septum formation initiator zf-C3HC4_2 PF13923.1 CDO69327.1 - 4.3e-08 33.0 3.3 9.3e-08 31.9 2.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO69327.1 - 1e-07 31.6 7.6 1.8e-07 30.8 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CDO69327.1 - 2.3e-07 30.3 4.9 3.6e-07 29.7 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO69327.1 - 1.2e-06 28.0 2.3 2.7e-06 26.9 1.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO69327.1 - 1.1e-05 25.1 5.2 2e-05 24.2 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CDO69327.1 - 0.0001 22.1 3.3 0.0001 22.1 2.3 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CDO69327.1 - 0.00026 20.6 2.7 0.00055 19.6 1.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CDO69327.1 - 0.0069 16.1 0.8 0.0069 16.1 0.5 1.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein HALZ PF02183.13 CDO69327.1 - 0.04 13.6 0.5 0.095 12.4 0.2 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Tmpp129 PF10272.4 CDO69327.1 - 0.21 10.2 2.3 0.32 9.6 1.6 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor Nucleopor_Nup85 PF07575.8 CDO69328.1 - 6.4e-53 179.8 0.0 5.1e-34 117.4 0.0 2.0 2 0 0 2 2 2 2 Nup85 Nucleoporin Histone PF00125.19 CDO69329.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CDO69329.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CDO69329.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CDO69329.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CDO69329.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CDO69329.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 CDO69330.1 - 5.5e-30 103.2 0.7 9.4e-30 102.5 0.5 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CDO69330.1 - 2.2e-05 24.5 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CDO69330.1 - 0.0026 17.8 0.1 0.0055 16.7 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CDO69330.1 - 0.02 14.1 2.3 0.024 13.9 1.6 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CDO69330.1 - 0.079 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Carb_kinase PF01256.12 CDO69331.1 - 4.6e-45 153.7 0.0 1.8e-43 148.5 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase GMC_oxred_N PF00732.14 CDO69332.1 - 2.3e-66 223.9 0.0 2.8e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CDO69332.1 - 1.6e-05 23.9 0.2 0.0057 15.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 CDO69332.1 - 0.0011 17.9 0.1 1.1 8.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CDO69332.1 - 0.0048 15.8 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 CDO69332.1 - 0.0069 16.3 0.0 0.043 13.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDO69332.1 - 0.0083 16.0 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDO69332.1 - 0.016 15.3 0.0 5.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mo-co_dimer PF03404.11 CDO69334.1 - 2.2e-23 82.3 2.4 3.3e-21 75.2 0.1 2.4 1 1 1 2 2 2 2 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 CDO69334.1 - 3.5e-23 81.8 0.0 6.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.16 CDO69334.1 - 1.5e-20 73.8 0.0 1.1e-19 70.9 0.0 2.5 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 CDO69334.1 - 1.3e-14 53.6 0.1 3.5e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 CDO69334.1 - 0.0036 17.2 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain CbiG_N PF11760.3 CDO69334.1 - 0.079 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal TPR_11 PF13414.1 CDO69335.1 - 4e-18 64.8 26.0 0.00038 20.0 0.0 8.3 8 1 1 9 9 9 5 TPR repeat TPR_19 PF14559.1 CDO69335.1 - 3.1e-13 49.8 23.0 5.2e-05 23.5 0.0 8.7 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 CDO69335.1 - 3.1e-12 45.3 12.1 2.8 7.9 0.0 9.7 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 CDO69335.1 - 3.8e-12 45.9 30.2 0.00016 21.5 0.4 8.7 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 CDO69335.1 - 8.2e-12 45.4 35.8 5.4e-05 23.7 0.0 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 CDO69335.1 - 4.2e-09 36.2 32.7 0.25 12.0 0.0 12.4 10 2 2 12 12 12 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDO69335.1 - 3e-07 29.8 30.8 0.6 10.1 0.0 10.7 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 CDO69335.1 - 4.1e-07 29.2 20.7 0.63 9.9 0.0 8.5 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDO69335.1 - 2.6e-06 26.7 17.1 4.4 7.0 0.1 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CDO69335.1 - 3.4e-06 27.3 1.5 0.0086 16.3 0.0 3.7 3 0 0 3 3 3 2 Alkyl sulfatase dimerisation Apc3 PF12895.2 CDO69335.1 - 2.4e-05 24.3 18.1 3.2 7.9 0.2 7.3 6 4 1 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CDO69335.1 - 4.4e-05 23.3 10.3 3.4 8.1 0.0 7.4 8 1 0 8 8 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDO69335.1 - 7.8e-05 22.8 12.3 0.11 13.0 0.0 8.6 10 0 0 10 10 8 1 Tetratricopeptide repeat NARP1 PF12569.3 CDO69335.1 - 0.00035 19.4 3.4 0.082 11.6 0.0 3.6 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 SNAP PF14938.1 CDO69335.1 - 0.07 12.2 3.9 0.043 12.9 0.3 2.4 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_9 PF13371.1 CDO69335.1 - 0.39 10.6 0.0 0.39 10.6 0.0 5.5 5 1 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 CDO69335.1 - 0.71 10.0 15.2 0.18 11.9 0.1 5.9 8 0 0 8 8 5 0 Tetratricopeptide repeat PAP2 PF01569.16 CDO69337.1 - 5.6e-09 35.7 8.3 7.8e-09 35.2 5.7 1.2 1 0 0 1 1 1 1 PAP2 superfamily MFS_1 PF07690.11 CDO69337.1 - 0.0065 15.2 1.1 0.0076 15.0 0.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SLAC1 PF03595.12 CDO69337.1 - 0.0067 15.1 5.1 0.0085 14.7 3.5 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel MFS_1 PF07690.11 CDO69338.1 - 4.8e-33 114.3 29.4 4.8e-33 114.3 20.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.5 CDO69338.1 - 0.066 12.8 0.4 0.52 9.8 0.2 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Vpu PF00558.14 CDO69338.1 - 0.094 12.2 0.7 0.36 10.4 0.1 2.2 2 0 0 2 2 2 0 Vpu protein BCS1_N PF08740.6 CDO69340.1 - 5.4e-20 71.8 1.1 1.2e-18 67.3 0.8 2.2 1 1 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CDO69340.1 - 4.6e-15 55.9 0.0 2.6e-08 34.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDO69340.1 - 6.1e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 CDO69340.1 - 0.0036 16.4 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 CDO69340.1 - 0.0072 15.2 0.0 0.022 13.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CDO69340.1 - 0.02 15.6 0.0 0.055 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CDO69340.1 - 0.021 14.7 0.6 0.15 12.0 0.0 2.4 2 1 1 3 3 3 0 AAA ATPase domain DFF-C PF09033.5 CDO69340.1 - 0.043 13.6 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain AAA_25 PF13481.1 CDO69340.1 - 0.092 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CDO69340.1 - 0.12 11.9 0.2 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CDO69340.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 BCS1_N PF08740.6 CDO69341.1 - 7e-24 84.4 0.1 1.3e-23 83.5 0.1 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CDO69341.1 - 1.9e-15 57.2 0.0 1.3e-14 54.4 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDO69341.1 - 0.00079 19.4 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 CDO69341.1 - 0.0018 17.2 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CDO69341.1 - 0.0027 16.7 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CDO69341.1 - 0.0058 17.4 0.0 0.019 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDO69341.1 - 0.0074 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 CDO69341.1 - 0.024 14.2 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 CDO69341.1 - 0.033 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CDO69341.1 - 0.037 14.1 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CDO69341.1 - 0.039 14.1 0.1 0.98 9.6 0.0 2.8 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.1 CDO69341.1 - 0.045 13.3 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CDO69341.1 - 0.049 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 CDO69341.1 - 0.062 13.0 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 1 0 Archaeal ATPase AAA_33 PF13671.1 CDO69341.1 - 0.081 12.7 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CDO69341.1 - 0.091 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-C2H2 PF00096.21 CDO69342.1 - 2.1e-09 37.1 3.6 0.00029 21.0 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO69342.1 - 8.1e-08 32.0 9.0 0.00077 19.6 0.4 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CDO69342.1 - 0.00051 20.1 9.6 1.5 9.2 0.0 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 CDO69342.1 - 0.00068 19.7 1.5 0.042 14.0 0.3 2.5 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-BED PF02892.10 CDO69342.1 - 0.043 13.5 1.5 7.8 6.3 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger CsbD PF05532.7 CDO69343.1 - 3e-15 55.6 10.2 8.7e-09 34.9 0.6 2.1 1 1 1 2 2 2 2 CsbD-like CsbD PF05532.7 CDO69344.1 - 5.6e-16 57.9 13.3 1.8e-08 33.9 1.9 2.0 1 1 1 2 2 2 2 CsbD-like zf-C2H2_6 PF13912.1 CDO69347.1 - 0.85 9.6 4.2 0.28 11.1 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_16 PF00722.16 CDO69351.1 - 1.1e-09 37.8 0.0 1.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WD40 PF00400.27 CDO69352.1 - 1.2e-32 110.5 12.5 1.9e-06 27.5 0.7 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat SIR2 PF02146.12 CDO69353.1 - 3.2e-29 101.9 0.0 4.4e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF4451 PF14616.1 CDO69355.1 - 1.4e-07 31.2 4.9 0.016 15.0 0.1 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4451) DUF3279 PF11682.3 CDO69355.1 - 0.019 14.5 3.0 0.96 9.0 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3279) zf-ribbon_3 PF13248.1 CDO69355.1 - 0.053 12.7 1.8 6.3 6.1 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-dskA_traR PF01258.12 CDO69355.1 - 0.088 12.5 0.6 3 7.6 0.1 2.6 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.2 CDO69355.1 - 0.62 9.9 4.9 19 5.1 1.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon Methyltransf_16 PF10294.4 CDO69356.1 - 2.4e-16 59.6 0.0 3.3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CDO69356.1 - 4.3e-08 33.7 0.0 8.3e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDO69356.1 - 0.0011 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CDO69356.1 - 0.0072 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CDO69356.1 - 0.0074 15.9 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 CDO69356.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 CDO69356.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PrmA PF06325.8 CDO69356.1 - 0.048 12.7 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pkinase PF00069.20 CDO69357.1 - 4.3e-41 140.7 0.0 5.8e-39 133.8 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69357.1 - 2e-17 63.1 0.0 2.9e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO69357.1 - 2.7e-06 27.2 0.1 6.1e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CDO69357.1 - 0.00015 20.8 0.0 0.00029 19.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDO69357.1 - 0.00058 18.9 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CDO69357.1 - 0.18 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 CDO69357.1 - 0.29 9.8 0.0 0.44 9.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cript PF10235.4 CDO69358.1 - 8.1e-22 77.3 6.0 8.1e-22 77.3 4.2 1.5 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT PHF5 PF03660.9 CDO69358.1 - 0.0045 17.0 4.4 0.0047 16.9 1.5 1.9 2 0 0 2 2 2 1 PHF5-like protein DUF2039 PF10217.4 CDO69358.1 - 0.02 14.9 11.9 0.023 14.7 5.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) stn_TNFRSF12A PF12191.3 CDO69358.1 - 0.032 14.2 1.5 0.032 14.2 1.0 1.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain zf-C3HC4_3 PF13920.1 CDO69358.1 - 0.83 9.3 10.3 14 5.4 4.7 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 CDO69358.1 - 1.3 8.7 7.1 1 9.0 2.6 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF1272 PF06906.6 CDO69358.1 - 1.3 8.8 7.6 0.46 10.3 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.1 CDO69358.1 - 3.2 7.1 10.3 3.8 6.8 1.9 3.0 3 0 0 3 3 3 0 zinc-ribbon domain XPA_N PF01286.13 CDO69358.1 - 3.3 7.4 0.0 3.3 7.4 0.0 3.3 4 0 0 4 4 4 0 XPA protein N-terminal Gin PF10764.4 CDO69358.1 - 4.8 6.9 8.3 11 5.7 0.0 3.1 2 1 1 3 3 3 0 Inhibitor of sigma-G Gin Prok-RING_1 PF14446.1 CDO69358.1 - 6.8 6.5 15.0 2.9 7.6 0.1 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 IgaA PF07095.6 CDO69359.1 - 0.042 11.6 0.1 0.051 11.3 0.1 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Ldl_recept_a PF00057.13 CDO69359.1 - 0.25 11.2 0.3 0.25 11.2 0.2 2.0 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Sec7 PF01369.15 CDO69361.1 - 1.8e-39 135.3 0.1 2.9e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain GATA PF00320.22 CDO69361.1 - 4.5e-15 54.7 2.6 9.1e-15 53.7 1.8 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 CDO69361.1 - 4.9e-13 48.4 1.7 9.3e-13 47.5 1.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Asp PF00026.18 CDO69362.1 - 4.5e-81 272.5 11.7 5.3e-81 272.3 8.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO69362.1 - 3e-10 40.2 0.9 9.2e-10 38.7 0.4 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO69362.1 - 0.0031 17.9 0.2 0.021 15.2 0.1 2.3 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 CDO69362.1 - 0.009 15.5 0.5 0.081 12.4 0.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF4230 PF14014.1 CDO69362.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) Peptidase_A22B PF04258.8 CDO69363.1 - 9.7e-64 215.6 6.1 1.1e-63 215.4 4.2 1.0 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 CDO69363.1 - 3.7e-06 26.2 1.8 9.4e-06 24.9 1.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) Presenilin PF01080.12 CDO69363.1 - 1.2 7.8 5.6 0.11 11.3 0.2 1.9 2 0 0 2 2 2 0 Presenilin SLAC1 PF03595.12 CDO69364.1 - 3.9e-69 232.8 38.8 4.5e-69 232.6 26.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.12 CDO69365.1 - 6.5e-75 251.8 50.3 7.4e-75 251.6 34.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1242 PF06842.7 CDO69365.1 - 0.018 14.5 1.1 0.075 12.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) PI3_PI4_kinase PF00454.22 CDO69366.1 - 2.3e-37 128.6 0.0 4.1e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RRM_1 PF00076.17 CDO69368.1 - 3.9e-13 48.8 0.1 2.2e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO69368.1 - 3.6e-12 46.0 0.1 6e-05 22.9 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO69368.1 - 1e-07 31.7 0.0 4.2e-06 26.5 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO69368.1 - 0.01 15.5 0.0 6.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif eIF-1a PF01176.14 CDO69369.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Peptidase_S10 PF00450.17 CDO69371.1 - 5.2e-71 240.0 4.6 6.2e-71 239.7 3.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PP2C PF00481.16 CDO69373.1 - 2.9e-64 216.9 0.1 1.9e-49 168.3 0.0 2.0 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CDO69373.1 - 1.9e-05 24.1 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 CDO69373.1 - 0.00024 20.8 0.4 0.0066 16.1 0.2 2.7 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) G_glu_transpept PF01019.16 CDO69374.1 - 7.6e-152 506.3 0.0 5.6e-151 503.5 0.0 1.9 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Cellulase PF00150.13 CDO69374.1 - 9.9e-28 97.1 7.2 1.4e-27 96.5 5.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 CDO69374.1 - 1.1e-12 47.3 9.7 2.4e-12 46.2 6.7 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase-like PF12876.2 CDO69374.1 - 0.0026 18.1 0.0 0.006 16.9 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 CDO69374.1 - 0.0034 16.3 0.0 0.011 14.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Asp PF00026.18 CDO69375.1 - 3.2e-13 49.6 0.0 3.4e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 CDO69375.1 - 0.003 17.1 0.0 0.003 17.1 0.0 1.1 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Oligomerisation PF02410.10 CDO69378.1 - 3.3e-07 30.2 0.0 5.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Oligomerisation domain SHR3_chaperone PF08229.6 CDO69379.1 - 6e-26 90.6 0.7 4.3e-25 87.8 0.5 1.9 1 1 0 1 1 1 1 ER membrane protein SH3 Linker_histone PF00538.14 CDO69380.1 - 2e-09 37.4 0.6 1.5e-08 34.5 0.0 2.7 3 0 0 3 3 3 1 linker histone H1 and H5 family ETS_PEA3_N PF04621.8 CDO69380.1 - 0.56 9.3 12.6 0.95 8.6 8.7 1.4 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Mitofilin PF09731.4 CDO69380.1 - 9.4 4.7 23.9 12 4.4 16.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CAP_N PF01213.14 CDO69382.1 - 2.1e-93 313.0 0.6 2.8e-93 312.6 0.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CDO69382.1 - 6.6e-52 175.0 7.1 3e-50 169.6 4.9 2.2 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 CDO69382.1 - 0.26 10.7 7.9 0.12 11.7 2.9 2.0 1 1 1 2 2 2 0 Tubulin binding cofactor C UQ_con PF00179.21 CDO69385.1 - 1.5e-43 147.5 0.2 1.9e-43 147.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDO69385.1 - 3.1e-06 26.9 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CDO69385.1 - 0.0046 16.6 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain TraK PF06586.6 CDO69385.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 TraK protein RVT_1 PF00078.22 CDO69391.1 - 6.3e-14 51.8 0.0 3e-13 49.6 0.0 2.1 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CDO69391.1 - 1.4e-09 37.5 0.0 4.4e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 CDO69391.1 - 0.00027 21.2 0.0 0.00083 19.7 0.0 1.8 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.1 CDO69391.1 - 0.00048 20.3 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase IL28A PF15177.1 CDO69391.1 - 0.078 12.4 2.7 11 5.5 0.1 3.1 3 0 0 3 3 3 0 Interleukin-28A Laminin_II PF06009.7 CDO69391.1 - 0.16 11.6 0.3 0.36 10.6 0.2 1.5 1 0 0 1 1 1 0 Laminin Domain II UBN2_3 PF14244.1 CDO69395.1 - 0.017 14.6 0.0 0.027 14.0 0.0 1.3 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO69395.1 - 0.021 14.2 0.9 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Uds1 PF15456.1 CDO69395.1 - 0.034 14.1 0.1 0.038 13.9 0.1 1.0 1 0 0 1 1 1 0 Up-regulated During Septation TMEM247 PF15444.1 CDO69397.1 - 1.8 8.3 7.4 2.7 7.7 5.1 1.4 1 1 0 1 1 1 0 Transmembrane protein 247 Asp_protease_2 PF13650.1 CDO69398.1 - 3e-07 30.8 0.0 6.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CDO69398.1 - 6.2e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 CDO69398.1 - 0.0028 17.4 3.7 0.0028 17.4 2.6 1.7 2 0 0 2 2 2 1 Zinc knuckle RVP PF00077.15 CDO69398.1 - 0.0034 17.2 0.0 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease MCLC PF05934.6 CDO69398.1 - 0.086 11.1 1.0 0.14 10.4 0.7 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) AvrE PF11725.3 CDO69398.1 - 0.48 7.3 6.2 0.72 6.7 4.3 1.2 1 0 0 1 1 1 0 Pathogenicity factor DUF4417 PF14386.1 CDO69400.1 - 0.029 13.7 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4417) NADH_B2 PF14813.1 CDO69401.1 - 0.0033 17.0 0.9 0.0036 16.9 0.4 1.3 1 1 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 G-alpha PF00503.15 CDO69402.1 - 1.6e-105 352.9 0.0 1.8e-105 352.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CDO69402.1 - 8.4e-15 54.4 0.0 4.8e-11 42.2 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO69402.1 - 2e-05 23.8 0.1 0.074 12.1 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 CDO69402.1 - 0.00038 19.9 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 CDO69402.1 - 0.0022 17.6 0.1 0.17 11.3 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.17 CDO69402.1 - 0.094 12.1 0.0 14 5.0 0.0 2.4 2 1 0 2 2 2 0 Ras family DUF755 PF05501.6 CDO69405.1 - 0.0021 18.0 7.5 0.0026 17.8 5.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF755) CENP-Q PF13094.1 CDO69405.1 - 0.11 12.5 13.9 0.14 12.1 9.7 1.0 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3619 PF12279.3 CDO69405.1 - 0.18 11.9 3.0 0.17 11.9 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF972 PF06156.8 CDO69405.1 - 0.25 11.6 9.0 0.28 11.5 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) YlqD PF11068.3 CDO69405.1 - 0.26 11.3 11.7 0.28 11.2 8.1 1.1 1 0 0 1 1 1 0 YlqD protein DUF1664 PF07889.7 CDO69405.1 - 0.42 10.4 2.6 0.47 10.2 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DDRGK PF09756.4 CDO69405.1 - 0.47 9.8 17.0 0.51 9.7 11.8 1.0 1 0 0 1 1 1 0 DDRGK domain Cob_adeno_trans PF01923.13 CDO69405.1 - 0.49 10.1 3.0 0.54 10.0 2.1 1.0 1 0 0 1 1 1 0 Cobalamin adenosyltransferase IncA PF04156.9 CDO69405.1 - 0.54 9.8 12.3 0.58 9.7 8.6 1.1 1 0 0 1 1 1 0 IncA protein CDC45 PF02724.9 CDO69405.1 - 0.61 8.0 8.8 0.63 7.9 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein MCPVI PF02993.9 CDO69405.1 - 0.63 10.1 7.9 0.68 10.0 5.5 1.0 1 0 0 1 1 1 0 Minor capsid protein VI Baculo_PP31 PF05311.6 CDO69405.1 - 0.99 8.6 8.5 1 8.5 5.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RRF PF01765.14 CDO69405.1 - 1 8.8 8.2 1.1 8.6 5.7 1.1 1 0 0 1 1 1 0 Ribosome recycling factor U79_P34 PF03064.11 CDO69405.1 - 1 8.8 10.6 1.1 8.7 7.4 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1266 PF06889.6 CDO69405.1 - 1.2 8.9 8.1 1.3 8.7 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF2968 PF11180.3 CDO69405.1 - 1.2 8.4 13.9 1.4 8.2 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Herpes_UL6 PF01763.11 CDO69405.1 - 1.3 7.0 5.8 1.5 6.9 4.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF3584 PF12128.3 CDO69405.1 - 1.6 5.9 12.7 1.5 6.0 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) STAG PF08514.6 CDO69405.1 - 1.6 8.4 6.0 2.1 8.0 4.2 1.2 1 0 0 1 1 1 0 STAG domain Caldesmon PF02029.10 CDO69405.1 - 1.8 6.8 19.9 2.1 6.6 13.8 1.0 1 0 0 1 1 1 0 Caldesmon DUF4407 PF14362.1 CDO69405.1 - 2 7.3 11.1 2 7.2 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.6 CDO69405.1 - 2.2 8.0 8.0 2.4 7.8 5.5 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Atg14 PF10186.4 CDO69405.1 - 2.2 7.1 10.2 2.3 7.1 7.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1764 PF08576.5 CDO69405.1 - 2.2 9.0 8.2 2.9 8.7 5.7 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) AKNA PF12443.3 CDO69405.1 - 2.3 8.2 9.2 0.32 11.0 2.5 1.9 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF3449 PF11931.3 CDO69405.1 - 2.4 7.6 8.2 2.8 7.4 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Mnd1 PF03962.10 CDO69405.1 - 2.5 7.7 14.5 2.9 7.5 10.0 1.1 1 0 0 1 1 1 0 Mnd1 family YqfQ PF14181.1 CDO69405.1 - 3.2 7.7 10.1 3.6 7.5 7.0 1.1 1 0 0 1 1 1 0 YqfQ-like protein FAM60A PF15396.1 CDO69405.1 - 3.2 7.4 7.0 3.5 7.3 4.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Vfa1 PF08432.5 CDO69405.1 - 3.5 7.6 15.3 3.8 7.4 10.6 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.5 CDO69405.1 - 3.6 7.3 9.7 4.2 7.1 6.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EMP24_GP25L PF01105.19 CDO69405.1 - 3.6 7.2 6.5 4.3 6.9 4.5 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD BORG_CEP PF14957.1 CDO69405.1 - 3.8 8.4 7.3 4.7 8.1 5.1 1.1 1 0 0 1 1 1 0 Cdc42 effector Ax_dynein_light PF10211.4 CDO69405.1 - 4 7.2 14.2 4.5 7.0 9.9 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain ATP11 PF06644.6 CDO69405.1 - 4.3 6.7 12.2 4.6 6.6 8.5 1.0 1 0 0 1 1 1 0 ATP11 protein SPX PF03105.14 CDO69405.1 - 4.6 6.9 9.7 5.2 6.7 6.7 1.0 1 0 0 1 1 1 0 SPX domain Trypan_glycop_C PF10659.4 CDO69405.1 - 4.6 7.6 8.7 5.9 7.2 6.0 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain OmpH PF03938.9 CDO69405.1 - 5.1 7.0 17.3 5.3 6.9 12.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2413 PF10310.4 CDO69405.1 - 5.8 5.6 14.7 7.1 5.3 10.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Mitofilin PF09731.4 CDO69405.1 - 5.9 5.4 15.9 5.8 5.4 11.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein COG2 PF06148.6 CDO69405.1 - 6.1 6.7 8.4 7 6.5 5.8 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 CDO69405.1 - 6.2 5.7 13.0 6.2 5.7 9.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 FemAB PF02388.11 CDO69405.1 - 6.6 5.2 10.4 7 5.2 7.2 1.0 1 0 0 1 1 1 0 FemAB family DUF1525 PF07511.6 CDO69405.1 - 7.2 6.6 8.3 9.4 6.2 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) DUF4139 PF13598.1 CDO69405.1 - 7.3 5.7 9.8 7.8 5.7 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) GrpE PF01025.14 CDO69405.1 - 8.1 5.9 15.5 9.5 5.7 10.7 1.1 1 0 0 1 1 1 0 GrpE GBP_C PF02841.9 CDO69405.1 - 8.3 5.4 15.0 9.4 5.3 10.4 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Lge1 PF11488.3 CDO69405.1 - 8.8 6.6 10.4 6.6 7.0 5.6 2.0 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 PV-1 PF06637.6 CDO69405.1 - 9.6 4.6 12.3 9.9 4.5 8.5 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) TMCO5 PF14992.1 CDO69405.1 - 9.9 5.1 11.0 11 5.0 7.6 1.0 1 0 0 1 1 1 0 TMCO5 family rve PF00665.21 CDO69406.1 - 1.3e-19 70.4 0.0 2.1e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CDO69406.1 - 0.0077 15.6 0.1 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 CDO69406.1 - 0.066 12.7 0.4 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain DLH PF01738.13 CDO69409.1 - 3.6e-24 85.2 0.0 4.1e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CDO69409.1 - 1.9e-06 27.7 0.0 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO69409.1 - 4.3e-06 26.7 0.1 0.00076 19.4 0.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family NmrA PF05368.8 CDO69410.1 - 1.7e-21 76.5 0.0 2.2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CDO69410.1 - 8.3e-16 58.5 0.0 1.4e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CDO69410.1 - 2.9e-05 22.9 0.0 4.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CDO69410.1 - 8.1e-05 22.1 0.0 0.00031 20.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CDO69410.1 - 0.00011 22.1 0.0 0.00071 19.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CDO69410.1 - 0.00094 18.8 0.0 0.025 14.2 0.0 2.2 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.13 CDO69410.1 - 0.034 14.1 0.0 0.098 12.6 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain UPF0104 PF03706.8 CDO69411.1 - 0.21 10.8 15.2 0.16 11.2 9.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) PepSY_TM PF03929.11 CDO69411.1 - 0.78 10.2 8.2 0.79 10.2 0.0 3.3 2 1 0 2 2 2 0 PepSY-associated TM helix Mito_carr PF00153.22 CDO69412.1 - 1.3e-47 159.4 3.0 8.5e-18 63.8 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 CDO69413.1 - 7.1e-23 80.8 41.4 3e-21 75.5 28.7 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1469 PF07332.6 CDO69413.1 - 0.045 13.4 0.2 0.045 13.4 0.1 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1469) PgaD PF13994.1 CDO69413.1 - 1.5 8.2 4.9 25 4.3 0.2 3.1 2 1 1 3 3 3 0 PgaD-like protein MFS_1 PF07690.11 CDO69415.1 - 9.6e-31 106.7 40.4 1.2e-30 106.3 28.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HMGL-like PF00682.14 CDO69416.1 - 5.9e-43 147.2 5.6 1.3e-23 83.9 0.0 2.9 2 1 1 3 3 3 2 HMGL-like LeuA_dimer PF08502.5 CDO69416.1 - 6.3e-11 42.1 0.3 1e-05 25.3 0.0 2.5 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain Ribosomal_S5 PF00333.15 CDO69416.1 - 0.00098 18.8 0.2 0.0028 17.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Aminotran_1_2 PF00155.16 CDO69417.1 - 4.6e-34 117.9 0.0 6.1e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CDO69417.1 - 6.9e-07 28.6 0.0 1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CDO69417.1 - 2.4e-05 22.7 0.0 5.4e-05 21.6 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CDO69417.1 - 3.7e-05 23.0 0.0 4.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CDO69417.1 - 0.0078 14.9 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CDO69418.1 - 0.15 10.9 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class I and II Dynamin_N PF00350.18 CDO69419.1 - 3.7e-16 59.3 5.5 4e-16 59.2 0.0 3.3 3 2 1 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 CDO69419.1 - 4.6e-07 29.8 0.0 0.00044 20.1 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.22 CDO69419.1 - 0.00032 20.9 2.6 0.00046 20.4 0.0 2.6 2 1 0 2 2 2 1 ABC transporter DUF258 PF03193.11 CDO69419.1 - 0.00083 18.5 0.0 0.0047 16.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 CDO69419.1 - 0.0013 19.1 0.0 0.0049 17.3 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CDO69419.1 - 0.0053 16.2 1.4 0.015 14.7 0.0 2.4 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_22 PF13401.1 CDO69419.1 - 0.0084 16.2 0.0 0.072 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CDO69419.1 - 0.018 15.0 1.5 0.18 11.7 0.0 3.3 4 0 0 4 4 3 0 AAA ATPase domain AAA_29 PF13555.1 CDO69419.1 - 0.027 13.9 0.1 0.065 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.11 CDO69419.1 - 0.028 13.5 0.1 0.095 11.7 0.1 1.9 1 0 0 1 1 1 0 AIG1 family AAA_10 PF12846.2 CDO69419.1 - 0.048 13.0 3.6 0.47 9.8 0.0 3.5 3 1 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 CDO69419.1 - 0.094 13.0 0.1 0.094 13.0 0.1 3.2 2 1 0 3 3 1 0 AAA domain ADIP PF11559.3 CDO69419.1 - 0.42 10.5 15.8 0.029 14.2 1.5 3.0 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 CDO69419.1 - 0.82 9.3 7.2 7 6.3 0.6 2.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Reo_sigmaC PF04582.7 CDO69419.1 - 2.5 7.1 7.9 3 6.9 0.9 2.4 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Aminotran_1_2 PF00155.16 CDO69420.1 - 1.2e-12 47.4 0.0 1.4e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CARD PF00619.16 CDO69421.1 - 0.07 12.9 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Caspase recruitment domain DUF615 PF04751.9 CDO69421.1 - 0.086 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Pkinase PF00069.20 CDO69422.1 - 0.0032 16.6 0.0 3.6 6.6 0.0 2.7 2 1 1 3 3 3 2 Protein kinase domain Aminotran_1_2 PF00155.16 CDO69423.1 - 1.2e-16 60.6 0.0 1.2e-14 54.0 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class I and II Pkinase PF00069.20 CDO69424.1 - 2.1e-16 59.8 0.0 2.1e-14 53.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69424.1 - 4.8e-06 25.8 0.1 2.5e-05 23.4 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CDO69424.1 - 0.016 14.9 0.1 0.047 13.4 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3410 PF11890.3 CDO69425.1 - 0.00013 21.4 0.1 0.00035 20.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3410) Pheromone PF08015.6 CDO69425.1 - 0.051 14.4 3.2 0.081 13.7 2.2 1.4 1 0 0 1 1 1 0 Fungal mating-type pheromone MHC2-interact PF09307.5 CDO69425.1 - 0.079 12.7 0.9 0.43 10.3 0.1 2.1 1 1 1 2 2 2 0 CLIP, MHC2 interacting RVT_connect PF06815.8 CDO69425.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase connection domain DUF4349 PF14257.1 CDO69425.1 - 1 8.5 3.1 0.82 8.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Pkinase PF00069.20 CDO69426.1 - 1.5e-16 60.3 0.0 2.1e-13 50.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69426.1 - 1.9e-06 27.1 0.1 1.5e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Melittin PF01372.12 CDO69427.1 - 0.1 11.9 0.4 0.18 11.2 0.3 1.3 1 0 0 1 1 1 0 Melittin DUF3416 PF11896.3 CDO69428.1 - 0.0063 16.4 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Pkinase PF00069.20 CDO69429.1 - 7e-18 64.7 0.0 1.6e-16 60.2 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69429.1 - 9.5e-05 21.5 0.1 0.00029 20.0 0.1 1.7 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 CDO69430.1 - 4e-21 75.3 0.1 2.6e-18 66.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69430.1 - 1.7e-06 27.2 0.9 5.5e-06 25.6 0.2 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.27 CDO69431.1 - 7.9e-30 101.6 16.9 5.3e-07 29.2 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CDO69431.1 - 0.00018 21.2 0.1 0.0077 15.9 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Bromodomain PF00439.20 CDO69432.1 - 6.5e-23 80.4 0.1 2e-22 78.9 0.1 1.9 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 CDO69432.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Pox_A_type_inc PF04508.7 CDO69432.1 - 5.7 6.9 6.7 67 3.6 0.0 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat UbiA PF01040.13 CDO69434.1 - 9.8e-26 90.5 11.1 9.8e-26 90.5 7.7 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Mpv17_PMP22 PF04117.7 CDO69435.1 - 0.49 10.0 7.1 0.57 9.8 3.3 2.2 2 0 0 2 2 2 0 Mpv17 / PMP22 family UbiA PF01040.13 CDO69436.1 - 2.6e-24 85.8 13.9 4.1e-24 85.1 9.7 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family RhodobacterPufX PF11511.3 CDO69436.1 - 2 7.8 5.5 0.41 10.0 0.5 2.3 3 0 0 3 3 3 0 Intrinsic membrane protein PufX Methyltransf_12 PF08242.7 CDO69438.1 - 1.9e-08 34.6 0.0 3.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO69438.1 - 3.9e-08 33.1 0.0 1.1e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO69438.1 - 3.9e-07 30.4 0.0 7.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO69438.1 - 2.5e-05 23.9 0.0 3.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO69438.1 - 5.5e-05 23.4 0.0 0.00013 22.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO69438.1 - 0.00073 20.1 0.0 0.0019 18.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain p450 PF00067.17 CDO69439.1 - 1.1e-58 198.9 0.0 3.5e-58 197.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 CDO69440.1 - 1.1e-24 86.6 0.3 2.4e-22 78.9 0.2 2.8 1 1 0 1 1 1 1 AMP-binding enzyme Aldose_epim PF01263.15 CDO69442.1 - 2e-46 158.5 0.5 2.9e-46 157.9 0.3 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase FAD_binding_3 PF01494.14 CDO69443.1 - 3.8e-12 45.9 3.5 5.7e-07 28.9 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain Trp_halogenase PF04820.9 CDO69443.1 - 7.8e-06 24.7 0.3 4.6e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 CDO69443.1 - 0.0012 18.6 1.0 0.022 14.5 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CDO69443.1 - 0.002 18.1 0.2 0.006 16.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDO69443.1 - 0.11 12.3 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 CDO69444.1 - 6.5e-57 192.9 0.0 1e-56 192.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO69444.1 - 3.7e-34 118.0 0.0 7.2e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CDO69444.1 - 1e-05 24.6 2.0 9.3e-05 21.4 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CDO69444.1 - 2.5e-05 24.4 0.1 0.02 14.9 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO69444.1 - 5.9e-05 23.0 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CDO69444.1 - 0.0016 17.4 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CDO69444.1 - 0.0074 15.1 3.0 0.019 13.8 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CDO69444.1 - 0.023 14.5 0.8 0.054 13.3 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO69444.1 - 0.033 12.6 1.6 0.079 11.4 0.2 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 CDO69444.1 - 0.07 12.2 0.2 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 CDO69444.1 - 1.2 9.5 3.8 2.7 8.4 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Helicase_C PF00271.26 CDO69447.1 - 3.8e-16 58.7 0.0 1.1e-15 57.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO69447.1 - 1.9e-05 24.2 0.0 4.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Abhydrolase_6 PF12697.2 CDO69448.1 - 2.7e-12 47.0 7.0 2.5e-06 27.5 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO69448.1 - 2.1e-05 24.2 0.3 3e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 CDO69449.1 - 5.1e-51 168.8 34.6 6e-12 44.9 0.0 11.6 12 0 0 12 12 12 9 WD domain, G-beta repeat eIF2A PF08662.6 CDO69449.1 - 6e-08 32.6 0.0 0.00043 20.0 0.0 3.8 5 0 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A NACHT PF05729.7 CDO69449.1 - 1.2e-07 31.5 0.2 2.6e-07 30.4 0.1 1.6 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 CDO69449.1 - 3.2e-05 24.0 0.0 0.0001 22.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDO69449.1 - 8.2e-05 22.6 0.5 0.00062 19.8 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain Cytochrom_D1 PF02239.11 CDO69449.1 - 0.0008 17.8 0.0 2.4 6.3 0.0 3.9 3 1 1 4 4 4 2 Cytochrome D1 heme domain Nup160 PF11715.3 CDO69449.1 - 0.0045 15.1 0.4 0.14 10.2 0.1 2.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 NB-ARC PF00931.17 CDO69449.1 - 0.012 14.4 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 CDO69449.1 - 0.023 14.2 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain LemA PF04011.7 CDO69449.1 - 0.081 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 LemA family KAP_NTPase PF07693.9 CDO69449.1 - 0.12 11.3 1.0 0.25 10.2 0.6 1.5 1 1 0 1 1 1 0 KAP family P-loop domain Abhydrolase_6 PF12697.2 CDO69450.1 - 2.2e-20 73.5 3.0 2.7e-20 73.2 2.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO69450.1 - 5e-05 23.0 0.0 9.5e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CDO69450.1 - 0.098 11.5 0.1 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Glyco_hydro_92 PF07971.7 CDO69451.1 - 9e-144 479.8 0.2 1.2e-143 479.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 GMC_oxred_N PF00732.14 CDO69452.1 - 7.4e-55 186.1 0.0 1e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO69452.1 - 3.1e-36 124.8 0.0 5.2e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 CDO69452.1 - 0.004 17.1 0.1 0.0091 16.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CDO69452.1 - 0.035 13.0 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 CDO69452.1 - 0.053 12.4 0.6 0.15 10.9 0.2 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDO69452.1 - 0.14 10.9 1.0 0.4 9.4 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_92 PF07971.7 CDO69453.1 - 2.8e-143 478.2 1.5 3.5e-143 477.8 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Prenyltrans PF00432.16 CDO69453.1 - 1.1 8.8 4.3 0.59 9.7 0.9 2.2 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Glyco_hydro_3 PF00933.16 CDO69454.1 - 1.1e-60 205.1 0.0 1.5e-60 204.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CDO69454.1 - 1.1e-47 162.5 0.0 1.7e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CDO69454.1 - 2e-22 78.8 1.6 3.9e-22 77.9 1.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain SH3_9 PF14604.1 CDO69455.1 - 2.1e-05 23.9 0.0 4.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CDO69455.1 - 0.00046 19.5 0.0 0.0011 18.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CDO69455.1 - 0.032 13.7 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain MFS_1 PF07690.11 CDO69456.1 - 7.9e-22 77.4 18.8 7.9e-22 77.4 13.0 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_10 PF00331.15 CDO69458.1 - 1.6e-91 306.7 0.0 2e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 CDO69458.1 - 1e-07 31.4 3.4 1e-07 31.4 2.3 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF4339 PF14237.1 CDO69458.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) TALPID3 PF15324.1 CDO69458.1 - 6.2 4.0 9.2 2.9 5.1 4.2 1.7 2 0 0 2 2 2 0 Hedgehog signalling target IMPDH PF00478.20 CDO69459.1 - 1.5e-136 454.9 0.0 5e-136 453.2 0.0 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CDO69459.1 - 1.6e-21 75.7 0.3 4.1e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 CDO69459.1 - 1.9e-10 40.1 4.9 7.2e-10 38.2 3.4 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 CDO69459.1 - 4.5e-09 35.8 9.0 2.1e-06 27.1 4.3 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.9 CDO69459.1 - 0.00014 21.0 1.1 0.00039 19.5 0.7 1.8 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 CDO69459.1 - 0.00019 20.7 5.3 0.00052 19.3 0.7 2.8 2 1 1 3 3 3 1 Histidine biosynthesis protein Aldolase PF01081.14 CDO69459.1 - 0.023 13.8 0.4 0.47 9.5 0.0 2.8 3 0 0 3 3 3 0 KDPG and KHG aldolase HK PF02110.10 CDO69459.1 - 0.038 13.1 3.2 0.11 11.6 0.1 2.7 2 1 0 3 3 3 0 Hydroxyethylthiazole kinase family Dus PF01207.12 CDO69459.1 - 0.08 11.7 1.4 1.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Glu_synthase PF01645.12 CDO69459.1 - 0.47 9.3 4.4 0.95 8.3 2.1 2.0 2 0 0 2 2 2 0 Conserved region in glutamate synthase Glyco_hydro_61 PF03443.9 CDO69461.1 - 1.1e-68 231.3 0.4 1.1e-68 231.3 0.3 1.7 2 0 0 2 2 1 1 Glycosyl hydrolase family 61 DnaJ PF00226.26 CDO69461.1 - 1.7e-21 75.7 0.5 1.7e-21 75.7 0.4 2.7 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 CDO69461.1 - 1.7e-17 62.8 16.4 7e-11 41.6 0.9 5.7 6 0 0 6 6 6 3 TPR repeat TPR_2 PF07719.12 CDO69461.1 - 5.7e-14 50.8 15.0 0.0024 17.6 0.1 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CDO69461.1 - 4.3e-13 48.6 11.4 0.26 12.0 0.1 7.0 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 CDO69461.1 - 4.4e-12 46.3 13.2 1e-07 32.4 1.0 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 CDO69461.1 - 2e-11 43.5 10.8 0.00026 20.7 0.4 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDO69461.1 - 4.9e-11 41.7 11.3 0.00013 21.4 0.1 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CDO69461.1 - 1.8e-09 37.8 18.4 0.0011 19.2 1.5 7.0 4 2 3 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 CDO69461.1 - 3.3e-08 33.5 6.9 1e-05 25.5 1.3 3.1 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CDO69461.1 - 4.9e-06 25.9 6.6 0.24 11.2 0.0 6.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDO69461.1 - 3.2e-05 23.7 9.3 0.0063 16.4 0.6 4.5 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.1 CDO69461.1 - 0.00011 22.4 15.4 0.31 11.5 0.1 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CDO69461.1 - 0.00047 19.7 5.1 1.3 8.9 0.1 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDO69461.1 - 0.0011 18.9 6.1 0.019 15.0 0.3 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.12 CDO69461.1 - 0.0098 16.2 6.9 0.096 12.9 0.1 3.7 2 1 0 3 3 3 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 CDO69461.1 - 0.023 14.5 2.1 0.32 10.9 0.0 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 CDO69461.1 - 0.07 13.2 8.6 0.36 10.9 0.2 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3775 PF12616.3 CDO69461.1 - 0.088 12.6 0.7 6.5 6.6 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3775) TPR_10 PF13374.1 CDO69461.1 - 0.69 9.9 5.9 12 5.9 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 CDO69461.1 - 2.6 8.7 11.3 17 6.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat VGCC_alpha2 PF08473.6 CDO69462.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd Complex1_LYR_2 PF13233.1 CDO69463.1 - 0.074 13.5 0.0 0.41 11.1 0.0 2.2 1 1 1 2 2 2 0 Complex1_LYR-like TIP49 PF06068.8 CDO69466.1 - 3.7e-177 589.0 0.0 4.2e-177 588.8 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CDO69466.1 - 5.4e-11 42.8 0.1 1e-07 32.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDO69466.1 - 5.4e-10 38.7 0.5 2.9e-08 33.0 0.0 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CDO69466.1 - 1.2e-08 35.1 0.0 3.8e-07 30.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CDO69466.1 - 1.9e-06 28.0 0.1 0.014 15.4 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CDO69466.1 - 2.8e-06 27.0 0.1 0.0014 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CDO69466.1 - 5.7e-05 22.7 0.0 0.00023 20.8 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CDO69466.1 - 0.00064 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 CDO69466.1 - 0.00096 18.6 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDO69466.1 - 0.00098 19.0 0.0 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CDO69466.1 - 0.0026 18.5 0.0 0.0093 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CDO69466.1 - 0.0027 17.6 0.1 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CDO69466.1 - 0.0046 16.1 0.1 0.021 13.9 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CDO69466.1 - 0.0048 16.0 0.3 0.011 14.7 0.1 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 CDO69466.1 - 0.0099 15.7 0.0 4 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 CDO69466.1 - 0.016 14.6 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 CDO69466.1 - 0.026 14.8 0.1 0.099 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CDO69466.1 - 0.056 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 CDO69466.1 - 0.057 12.6 0.0 0.17 11.0 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 CDO69466.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 CDO69466.1 - 0.14 10.9 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 CDO69466.1 - 0.18 12.0 0.0 0.5 10.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CBFD_NFYB_HMF PF00808.18 CDO69467.1 - 5.7e-20 71.1 1.7 9.9e-20 70.3 1.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CDO69467.1 - 1.6e-09 37.7 0.1 2.4e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 CDO69467.1 - 0.0069 16.1 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.12 CDO69467.1 - 0.096 12.6 0.2 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Cu-oxidase PF00394.17 CDO69469.1 - 2.2e-51 173.9 0.4 2.7e-47 160.6 0.0 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CDO69469.1 - 2.9e-39 133.4 3.3 1.7e-37 127.7 0.1 3.6 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CDO69469.1 - 1.6e-35 121.5 6.0 5.1e-33 113.4 0.3 3.6 3 1 0 3 3 3 2 Multicopper oxidase 2OG-FeII_Oxy PF03171.15 CDO69471.1 - 0.021 15.0 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CDO69472.1 - 3.3e-17 63.0 0.0 5.6e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO69472.1 - 8.1e-14 51.7 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CDO69473.1 - 1e-13 51.8 0.0 1.9e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO69473.1 - 4e-13 49.5 0.0 1.4e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Meth_synt_2 PF01717.13 CDO69475.1 - 3.5e-18 65.6 0.0 1.1e-12 47.5 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CDO69475.1 - 2.8e-07 30.1 0.0 0.0088 15.3 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain zf-H2C2_2 PF13465.1 CDO69477.1 - 8.5e-06 25.8 12.4 0.0023 18.1 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CDO69477.1 - 1.4e-05 25.0 19.9 0.0042 17.3 4.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO69477.1 - 0.00037 20.6 13.9 0.089 13.1 4.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CDO69477.1 - 0.11 12.7 8.3 0.34 11.1 2.7 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CDO69477.1 - 1.7 8.4 10.2 3.8 7.2 2.9 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 CDO69477.1 - 1.7 8.9 9.5 0.44 10.7 2.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding WD40 PF00400.27 CDO69478.1 - 9.4e-28 95.0 9.7 2.1e-06 27.3 0.8 6.5 6 1 0 6 6 6 6 WD domain, G-beta repeat PNP_UDP_1 PF01048.15 CDO69479.1 - 2.8e-35 121.3 0.0 3.4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF659 PF04937.10 CDO69480.1 - 1.7e-07 30.8 0.1 3.1e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Velvet PF11754.3 CDO69481.1 - 0.011 15.2 0.1 0.011 15.2 0.0 1.1 1 0 0 1 1 1 0 Velvet factor AIP3 PF03915.8 CDO69483.1 - 2.2e-16 59.8 7.2 2.5e-16 59.6 5.0 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 CheZ PF04344.8 CDO69483.1 - 0.017 14.7 1.8 0.019 14.6 1.2 1.0 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Tmemb_cc2 PF10267.4 CDO69483.1 - 0.039 12.5 4.1 0.042 12.4 2.8 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TBPIP PF07106.8 CDO69483.1 - 0.074 12.6 1.8 0.083 12.4 1.3 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Muted PF14942.1 CDO69483.1 - 0.087 12.6 3.1 0.11 12.4 2.2 1.0 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein FF PF01846.14 CDO69483.1 - 0.11 12.5 2.9 0.3 11.0 2.0 1.8 1 1 0 1 1 1 0 FF domain Imm42 PF15601.1 CDO69483.1 - 0.12 11.8 1.9 0.14 11.5 1.3 1.0 1 0 0 1 1 1 0 Immunity protein 42 AbiH PF14253.1 CDO69483.1 - 0.12 11.9 1.6 0.14 11.7 1.1 1.0 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH APG6 PF04111.7 CDO69483.1 - 0.19 10.7 5.4 0.22 10.5 3.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 HMG_box PF00505.14 CDO69487.1 - 0.09 13.0 0.4 0.34 11.1 0.1 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box FGase PF05013.7 CDO69488.1 - 0.058 13.2 0.2 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase DUF3258 PF11646.3 CDO69490.1 - 0.11 12.7 0.0 23 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF3258 Retrotrans_gag PF03732.12 CDO69492.1 - 0.0013 18.7 0.0 0.0088 16.0 0.0 2.2 1 1 1 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.22 CDO69493.1 - 3.2e-23 82.2 0.0 5.5e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glypican PF01153.14 CDO69494.1 - 0.29 9.6 11.9 1.6 7.2 2.7 3.0 3 0 0 3 3 3 0 Glypican TSA PF03249.8 CDO69494.1 - 1.3 7.5 6.1 2.1 6.7 4.2 1.3 1 0 0 1 1 1 0 Type specific antigen DTHCT PF08070.6 CDO69494.1 - 1.7 9.3 10.7 24 5.6 4.2 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF755 PF05501.6 CDO69494.1 - 2.3 8.2 8.8 3.5 7.7 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MEF2_binding PF09047.5 CDO69495.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 MEF2 binding DUF659 PF04937.10 CDO69496.1 - 2e-07 30.6 0.1 3.6e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) K_oxygenase PF13434.1 CDO69497.1 - 3.4e-37 128.1 0.0 3.8e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AMP-binding PF00501.23 CDO69498.1 - 1.6e-91 306.8 0.0 1.9e-91 306.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 CDO69498.1 - 0.0057 15.2 0.0 1.7 7.0 0.0 2.1 2 0 0 2 2 2 2 GH3 auxin-responsive promoter Condensation PF00668.15 CDO69499.1 - 1.3e-99 332.8 0.1 2.4e-34 118.5 0.1 3.4 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 CDO69499.1 - 1.5e-34 118.0 0.2 3.4e-10 40.0 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site dCMP_cyt_deam_1 PF00383.17 CDO69500.1 - 1e-14 53.9 0.0 1.7e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 CDO69500.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.4 1 1 0 1 1 1 0 APOBEC-like N-terminal domain SH2_2 PF14633.1 CDO69501.1 - 5.6e-70 234.8 0.3 5.6e-70 234.8 0.2 2.2 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 CDO69501.1 - 2.2e-32 111.5 0.9 2.2e-32 111.5 0.6 2.7 2 0 0 2 2 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 CDO69501.1 - 2.1e-31 108.0 0.1 4.2e-31 107.1 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 CDO69501.1 - 2.5e-30 105.0 0.0 6e-30 103.8 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 CDO69501.1 - 4.8e-19 68.3 27.1 4.8e-19 68.3 18.8 6.3 7 1 2 9 9 9 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 CDO69501.1 - 3e-15 56.2 0.0 1e-14 54.5 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 CDO69501.1 - 5.6e-08 32.4 0.0 9.2e-07 28.5 0.0 2.8 3 0 0 3 3 3 1 SH2 domain HHH_3 PF12836.2 CDO69501.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.18 CDO69501.1 - 0.034 14.2 0.7 0.074 13.1 0.5 1.6 1 0 0 1 1 1 0 S1 RNA binding domain JmjC PF02373.17 CDO69502.1 - 1.6e-19 70.2 0.1 3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CDO69502.1 - 5.3e-19 68.7 0.4 7.6e-19 68.1 0.2 1.2 1 0 0 1 1 1 1 Cupin-like domain GPI PF06560.6 CDO69502.1 - 0.068 12.1 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Peptidase_M19 PF01244.16 CDO69503.1 - 1.4e-106 356.1 0.0 1.8e-106 355.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) WD40 PF00400.27 CDO69505.1 - 2.4e-15 55.7 15.4 0.007 16.2 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF2457 PF10446.4 CDO69505.1 - 4.1 6.0 13.0 6.2 5.4 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 CDO69505.1 - 8.5 4.1 11.6 10 3.8 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 CDO69505.1 - 9 5.8 8.3 19 4.7 5.8 1.5 1 0 0 1 1 1 0 YL1 nuclear protein SRP54 PF00448.17 CDO69506.1 - 2.3e-74 249.1 2.0 3.7e-74 248.4 1.4 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CDO69506.1 - 5.8e-24 84.3 3.1 1.5e-22 79.7 0.0 2.6 1 1 1 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.14 CDO69506.1 - 3.2e-14 52.7 2.3 7.2e-14 51.6 1.6 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 CDO69506.1 - 7.5e-07 29.1 0.1 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CDO69506.1 - 1.1e-06 28.1 0.3 2.5e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 CDO69506.1 - 0.0003 20.2 0.4 0.0016 17.8 0.3 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 CDO69506.1 - 0.00048 19.8 0.1 0.0011 18.6 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CDO69506.1 - 0.0016 17.2 2.6 0.0028 16.4 0.2 2.3 1 1 1 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 CDO69506.1 - 0.011 14.8 0.1 0.021 13.9 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_31 PF13614.1 CDO69506.1 - 0.021 14.7 0.0 10 6.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF1768 PF08719.6 CDO69506.1 - 0.028 14.1 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) AAA_30 PF13604.1 CDO69506.1 - 0.035 13.6 1.4 0.14 11.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDO69506.1 - 0.035 14.9 0.0 0.084 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3677 PF12432.3 CDO69506.1 - 0.075 13.4 0.0 17 5.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) DUF2201 PF09967.4 CDO69506.1 - 0.091 12.7 0.5 0.88 9.5 0.0 2.7 2 1 1 3 3 3 0 VWA-like domain (DUF2201) 6PF2K PF01591.13 CDO69506.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase RRM_1 PF00076.17 CDO69508.1 - 2e-46 155.4 0.0 1.9e-19 69.0 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CDO69508.1 - 4.3e-30 103.1 2.6 1.1e-29 101.9 1.4 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_6 PF14259.1 CDO69508.1 - 1.3e-29 101.9 0.0 3.2e-11 43.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO69508.1 - 2.7e-19 68.7 0.2 2.1e-08 33.8 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CDO69508.1 - 0.033 14.0 0.2 0.13 12.0 0.2 1.9 2 0 0 2 2 2 0 RNA binding motif DUF1494 PF07379.6 CDO69508.1 - 0.08 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) TC1 PF15063.1 CDO69508.1 - 0.12 11.8 0.1 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 Thyroid cancer protein 1 SCAMP PF04144.8 CDO69509.1 - 4.5e-47 160.2 5.3 5.3e-47 159.9 3.6 1.0 1 0 0 1 1 1 1 SCAMP family Nup54 PF13874.1 CDO69509.1 - 0.0012 18.4 0.1 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 DUF4200 PF13863.1 CDO69509.1 - 0.065 13.1 4.3 0.1 12.5 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DPBB_1 PF03330.13 CDO69510.1 - 2.9e-12 46.3 0.1 7.3e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CDO69510.1 - 2.1e-05 24.2 0.1 4.9e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Barwin family DUF605 PF04652.11 CDO69510.1 - 0.35 10.2 24.0 0.51 9.6 16.6 1.3 1 0 0 1 1 1 0 Vta1 like Nop14 PF04147.7 CDO69510.1 - 0.47 8.3 14.8 0.59 7.9 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CDO69510.1 - 9.1 5.4 12.1 12 5.0 8.4 1.1 1 0 0 1 1 1 0 SDA1 NAD_binding_10 PF13460.1 CDO69511.1 - 0.015 15.3 0.0 0.29 11.1 0.0 2.5 2 1 0 2 2 2 0 NADH(P)-binding NAD_binding_4 PF07993.7 CDO69511.1 - 0.03 13.2 0.0 0.044 12.6 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein MmoB_DmpM PF02406.12 CDO69511.1 - 0.039 13.9 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 MmoB/DmpM family ADK PF00406.17 CDO69512.1 - 4.9e-43 146.5 0.0 6.8e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CDO69512.1 - 1.1e-12 47.3 0.0 1.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CDO69512.1 - 1.8e-07 31.9 0.0 2.8e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDO69512.1 - 0.0001 22.6 0.1 0.00031 21.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDO69512.1 - 0.00018 21.3 0.1 0.0012 18.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain Curto_V3 PF07436.6 CDO69512.1 - 0.0056 16.7 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Curtovirus V3 protein Zeta_toxin PF06414.7 CDO69512.1 - 0.051 12.6 0.1 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Methyltransf_PK PF05891.7 CDO69513.1 - 4.3e-51 173.3 0.0 3.8e-32 111.3 0.0 2.8 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 CDO69513.1 - 1.1e-05 25.9 0.1 2.4e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO69513.1 - 0.00047 19.9 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO69513.1 - 0.00068 19.9 0.0 0.0038 17.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO69513.1 - 0.0013 19.1 0.0 0.06 13.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO69513.1 - 0.0078 16.6 0.0 3.1 8.3 0.0 2.4 1 1 0 2 2 2 2 Methyltransferase domain Swi3 PF07962.7 CDO69514.1 - 9.6e-14 50.7 0.1 4.2e-12 45.5 0.1 2.4 1 1 0 1 1 1 1 Replication Fork Protection Component Swi3 LamB PF02264.10 CDO69516.1 - 0.085 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 LamB porin DcpS_C PF11969.3 CDO69517.1 - 3.5e-10 40.1 1.5 8.8e-10 38.8 1.0 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-RING_3 PF14369.1 CDO69517.1 - 0.046 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 zinc-finger zf-C2H2_4 PF13894.1 CDO69517.1 - 0.046 14.0 0.2 0.12 12.7 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger HIT PF01230.18 CDO69517.1 - 0.089 13.3 7.1 0.3 11.6 2.9 2.8 2 1 0 2 2 2 0 HIT domain ox_reductase_C PF08635.5 CDO69518.1 - 8.7e-75 248.8 0.3 1.3e-74 248.3 0.2 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 CDO69518.1 - 2.4e-20 73.2 0.0 4.4e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CDO69518.1 - 0.05 13.3 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain SEEK1 PF15357.1 CDO69518.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 DUF972 PF06156.8 CDO69519.1 - 0.034 14.4 4.7 0.055 13.8 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spectrin PF00435.16 CDO69519.1 - 0.065 13.5 5.2 0.097 12.9 3.6 1.2 1 0 0 1 1 1 0 Spectrin repeat DUF4509 PF14970.1 CDO69519.1 - 0.1 12.2 1.0 0.15 11.7 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) T2SF PF00482.18 CDO69519.1 - 0.17 11.8 2.1 0.27 11.1 1.5 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F V_ATPase_I PF01496.14 CDO69519.1 - 0.22 9.3 1.0 0.25 9.1 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Matrilin_ccoil PF10393.4 CDO69519.1 - 0.24 10.7 1.8 0.4 10.0 1.2 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF3734 PF12536.3 CDO69519.1 - 0.47 10.5 4.1 1 9.5 2.8 1.5 1 0 0 1 1 1 0 Patatin phospholipase DUF484 PF04340.7 CDO69519.1 - 0.53 9.7 6.2 0.7 9.3 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF484 DUF2413 PF10310.4 CDO69519.1 - 0.89 8.2 7.1 2.6 6.7 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2413) Atg14 PF10186.4 CDO69519.1 - 0.93 8.3 6.9 1.2 8.0 4.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bap31 PF05529.7 CDO69519.1 - 7.2 6.0 6.5 9.7 5.5 4.5 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like SAP PF02037.22 CDO69521.1 - 3.5e-10 39.1 0.2 1.5e-09 37.1 0.1 2.0 2 0 0 2 2 2 1 SAP domain DUF2315 PF10231.4 CDO69522.1 - 3e-14 52.9 2.2 1.5e-11 44.2 0.3 2.1 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2315) Nucleoporin_C PF03177.9 CDO69523.1 - 1.5e-64 218.5 0.5 2.2e-64 218.0 0.4 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CDO69523.1 - 3.7e-18 65.4 0.0 5.1e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like PRCC PF10253.4 CDO69524.1 - 2e-35 123.1 1.1 2e-35 123.1 0.8 2.6 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Slu7 PF11708.3 CDO69524.1 - 1 9.0 8.0 0.64 9.7 4.1 1.7 1 1 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Histone PF00125.19 CDO69525.1 - 8.5e-22 77.0 0.1 1.2e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CDO69525.1 - 1.4e-05 25.0 0.0 1.4e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CDO69525.1 - 0.0021 18.2 0.0 0.004 17.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.6 CDO69525.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein MaoC_dehydratas PF01575.14 CDO69526.1 - 0.00015 21.0 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Transglut_core PF01841.14 CDO69526.1 - 0.042 14.0 0.1 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily Aminotran_5 PF00266.14 CDO69528.1 - 6.3e-33 114.0 0.0 9.9e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V RabGAP-TBC PF00566.13 CDO69529.1 - 1.7e-41 142.0 9.6 6e-39 133.7 6.7 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 CDO69529.1 - 2.2e-09 36.9 0.0 2.6e-05 23.6 0.0 3.3 2 1 0 2 2 2 2 Domain of unknown function (DUF3548) Lung_7-TM_R PF06814.8 CDO69529.1 - 0.13 11.2 1.3 0.2 10.5 0.9 1.2 1 0 0 1 1 1 0 Lung seven transmembrane receptor Ribosomal_S21e PF01249.13 CDO69530.1 - 6e-36 122.2 0.0 6.6e-36 122.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF917 PF06032.7 CDO69530.1 - 0.0031 16.1 0.0 0.0031 16.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF917) PAP2 PF01569.16 CDO69531.1 - 8.3e-20 70.7 5.9 1.3e-19 70.1 4.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily PSDC PF12588.3 CDO69532.1 - 1.3e-46 157.6 0.0 2.2e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 CDO69532.1 - 4.7e-35 120.7 0.0 6.2e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PPP4R2 PF09184.6 CDO69533.1 - 4.7e-26 92.0 0.0 7.1e-26 91.4 0.0 1.5 1 1 0 1 1 1 1 PPP4R2 DUF605 PF04652.11 CDO69534.1 - 4.7 6.5 16.5 6 6.1 11.4 1.2 1 0 0 1 1 1 0 Vta1 like SUI1 PF01253.17 CDO69535.1 - 1.3e-30 105.0 0.6 1.5e-30 104.8 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF1777 PF08648.7 CDO69536.1 - 8.1e-26 90.8 3.3 8.1e-26 90.8 2.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) SRP-alpha_N PF04086.8 CDO69536.1 - 0.028 13.8 1.0 0.033 13.5 0.7 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GSH_synth_ATP PF03917.12 CDO69537.1 - 3.6e-98 328.5 0.0 4.5e-98 328.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CDO69537.1 - 2.2e-33 114.4 0.0 4.8e-33 113.3 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic glutathione synthase Bac_rhodopsin PF01036.13 CDO69538.1 - 6.9e-36 123.6 18.3 8.5e-36 123.3 12.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein AAA PF00004.24 CDO69539.1 - 1.3e-44 151.5 0.1 4.5e-44 149.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDO69539.1 - 5.1e-09 35.9 0.1 2.1e-08 33.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CDO69539.1 - 5e-08 33.0 0.2 2.7e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CDO69539.1 - 4.3e-07 30.1 0.7 1.9e-06 27.9 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 CDO69539.1 - 1.1e-06 27.7 0.1 2.4e-06 26.6 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 CDO69539.1 - 9.2e-06 25.8 3.6 0.00035 20.7 0.4 3.0 3 1 0 3 3 1 1 AAA domain AAA_14 PF13173.1 CDO69539.1 - 7.9e-05 22.5 0.0 0.00059 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CDO69539.1 - 0.00011 22.5 0.0 0.0093 16.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CDO69539.1 - 0.00011 22.1 0.2 0.00037 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDO69539.1 - 0.00016 21.3 0.1 0.00043 19.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 CDO69539.1 - 0.00033 20.3 1.0 0.0065 16.1 0.0 3.2 4 0 0 4 4 4 1 NTPase AAA_17 PF13207.1 CDO69539.1 - 0.00056 20.7 0.0 0.0044 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CDO69539.1 - 0.00068 18.7 0.0 0.0016 17.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CDO69539.1 - 0.0016 18.1 0.1 0.054 13.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 CDO69539.1 - 0.0016 18.5 0.0 0.0049 17.0 0.0 1.8 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.8 CDO69539.1 - 0.0022 16.7 0.0 0.0044 15.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus UPF0079 PF02367.12 CDO69539.1 - 0.0026 17.3 0.1 0.023 14.3 0.0 2.2 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 CDO69539.1 - 0.0041 17.4 3.5 0.75 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CDO69539.1 - 0.0046 16.3 4.2 0.014 14.7 0.0 2.7 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CDO69539.1 - 0.0048 16.3 1.0 0.0098 15.3 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 CDO69539.1 - 0.0053 16.6 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 CDO69539.1 - 0.0058 16.2 1.6 0.016 14.8 0.0 2.2 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 CDO69539.1 - 0.0067 15.6 0.1 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CDO69539.1 - 0.0071 15.9 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CDO69539.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CDO69539.1 - 0.014 15.0 0.1 0.033 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CDO69539.1 - 0.016 14.8 1.4 0.16 11.6 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase Zeta_toxin PF06414.7 CDO69539.1 - 0.019 14.0 0.0 0.041 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AFG1_ATPase PF03969.11 CDO69539.1 - 0.025 13.3 0.0 0.051 12.3 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase T2SE PF00437.15 CDO69539.1 - 0.035 13.0 0.0 0.081 11.8 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein Bac_DnaA PF00308.13 CDO69539.1 - 0.035 13.7 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.21 CDO69539.1 - 0.066 12.6 0.3 1.1 8.7 0.0 2.7 3 1 0 3 3 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 CDO69539.1 - 0.1 12.9 0.4 0.51 10.6 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.12 CDO69539.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 CDO69539.1 - 0.15 11.1 2.4 0.38 9.8 0.0 2.5 3 0 0 3 3 3 0 KaiC P5CR_dimer PF14748.1 CDO69540.1 - 1.4e-39 134.3 4.7 2e-39 133.9 2.1 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CDO69540.1 - 0.00042 20.6 0.0 0.0018 18.6 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Glyco_tran_28_C PF04101.11 CDO69541.1 - 5.8e-27 94.3 0.0 7.1e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CDO69541.1 - 4.5e-05 22.7 0.0 6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 NAC PF01849.13 CDO69543.1 - 4.6e-23 80.5 0.0 9.9e-23 79.4 0.0 1.6 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CDO69543.1 - 0.0021 17.8 0.1 0.0064 16.3 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CDO69543.1 - 0.031 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Zip PF02535.17 CDO69543.1 - 0.076 12.0 1.4 0.07 12.1 1.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CKAP2_C PF15297.1 CDO69543.1 - 0.17 10.6 0.7 0.24 10.1 0.5 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF1373 PF07117.6 CDO69543.1 - 0.42 10.3 1.8 0.37 10.4 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) DUF1264 PF06884.6 CDO69544.1 - 2e-47 160.7 2.8 1e-44 152.0 2.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1264) Abhydrolase_3 PF07859.8 CDO69545.1 - 7.3e-34 117.1 0.0 9.9e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CDO69545.1 - 1.5e-13 50.1 0.0 2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 CDO69545.1 - 6e-05 23.0 1.0 9.3e-05 22.4 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CDO69545.1 - 0.0021 17.3 0.0 0.023 13.8 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDO69545.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 CDO69545.1 - 0.1 11.8 0.0 7 5.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2974 PF11187.3 CDO69545.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 CDO69546.1 - 4.4e-33 114.6 0.0 6.2e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CDO69546.1 - 3.1e-11 42.5 0.0 4.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 CDO69546.1 - 1.7e-05 23.7 0.0 2.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CDO69546.1 - 0.002 17.4 0.0 0.89 8.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.15 CDO69546.1 - 0.008 16.4 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 CDO69546.1 - 0.072 12.8 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hamartin PF04388.7 CDO69547.1 - 6.9e-14 51.4 17.8 1.7e-07 30.3 1.2 2.7 2 1 0 2 2 2 2 Hamartin protein Bap31 PF05529.7 CDO69547.1 - 2.3 7.6 14.2 0.73 9.2 4.2 2.6 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like HSP90 PF00183.13 CDO69548.1 - 9.6e-258 855.8 33.5 1.2e-257 855.6 23.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CDO69548.1 - 7.5e-13 48.1 0.0 1.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CDO69548.1 - 4.1e-11 42.6 0.1 4.1e-11 42.6 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 CDO69548.1 - 0.32 10.3 20.6 0.017 14.4 9.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Methyltransf_11 PF08241.7 CDO69549.1 - 6.6e-13 48.9 0.0 1.4e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO69549.1 - 2.1e-08 34.7 0.0 1.1e-06 29.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO69549.1 - 1.8e-07 31.0 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO69549.1 - 6.5e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO69549.1 - 1.1e-06 29.0 0.0 3.5e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO69549.1 - 0.00076 19.7 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 CDO69549.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Rsm22 PF09243.5 CDO69549.1 - 0.015 14.3 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 RVP_2 PF08284.6 CDO69550.1 - 8.5e-08 32.2 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CDO69550.1 - 3e-07 30.8 0.0 5.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO69550.1 - 1e-06 28.4 0.0 2.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 CDO69550.1 - 0.0043 16.3 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase Retrotrans_gag PF03732.12 CDO69551.1 - 2.5e-14 53.0 0.0 5.4e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 CDO69551.1 - 0.033 13.7 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO69551.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 CDO69551.1 - 0.21 11.2 0.3 0.33 10.6 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle RAP1 PF07218.6 CDO69551.1 - 1.4 6.9 5.4 1.8 6.5 3.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RVT_1 PF00078.22 CDO69552.1 - 9.4e-10 38.2 0.3 1.6e-09 37.4 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO69552.1 - 0.065 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO69553.1 - 1.8e-18 66.7 0.0 2.2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDO69553.1 - 0.004 16.6 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain FlxA PF14282.1 CDO69554.1 - 0.008 16.1 0.8 0.0098 15.8 0.6 1.1 1 0 0 1 1 1 1 FlxA-like protein DUF4075 PF13294.1 CDO69554.1 - 0.024 14.6 1.5 0.033 14.2 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) Methyltransf_1N PF02870.10 CDO69554.1 - 0.033 14.7 0.4 0.043 14.4 0.3 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain COG2 PF06148.6 CDO69554.1 - 0.046 13.5 0.2 0.054 13.3 0.2 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 RasGAP_C PF03836.10 CDO69554.1 - 0.057 13.1 0.4 0.063 12.9 0.3 1.1 1 0 0 1 1 1 0 RasGAP C-terminus DASH_Spc34 PF08657.5 CDO69554.1 - 0.085 12.5 3.7 0.09 12.4 2.5 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 Nop52 PF05997.7 CDO69554.1 - 0.094 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Streptin-Immun PF11083.3 CDO69554.1 - 0.17 11.8 2.0 0.23 11.4 1.4 1.2 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein APG6 PF04111.7 CDO69554.1 - 1.9 7.4 6.8 1.9 7.4 4.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CDO69554.1 - 4.8 6.7 8.1 12 5.4 5.5 1.6 1 1 0 1 1 1 0 IncA protein TEX19 PF15553.1 CDO69555.1 - 0.18 11.6 2.9 0.28 11.0 2.0 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 YqfQ PF14181.1 CDO69555.1 - 1.9 8.4 9.4 2.6 8.0 6.5 1.2 1 0 0 1 1 1 0 YqfQ-like protein Zn_clus PF00172.13 CDO69555.1 - 2.1 8.3 8.6 3 7.8 4.6 2.1 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Atrophin-1 PF03154.10 CDO69555.1 - 5.3 5.0 12.6 5.4 5.0 8.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family 2Fe-2S_thioredx PF01257.14 CDO69556.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Asp_protease_2 PF13650.1 CDO69557.1 - 0.0081 16.6 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CDO69557.1 - 0.037 13.5 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.21 CDO69558.1 - 1.9e-10 40.8 0.0 4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain F-box-like PF12937.2 CDO69563.1 - 0.0019 17.8 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 CDO69563.1 - 0.022 14.4 0.1 0.033 13.8 0.0 1.5 1 1 0 1 1 1 0 F-box-like domain DUF2009 PF09418.5 CDO69564.1 - 1.2e-206 686.9 0.0 1.3e-206 686.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) PCI PF01399.22 CDO69565.1 - 4.8e-08 33.2 0.0 5.6e-07 29.8 0.0 2.4 2 1 0 2 2 2 1 PCI domain HTH_23 PF13384.1 CDO69565.1 - 0.011 15.3 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Phage_terminase PF10668.4 CDO69565.1 - 0.11 12.2 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Phage terminase small subunit DFF40 PF09230.5 CDO69565.1 - 0.16 11.3 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa DUF2404 PF10296.4 CDO69566.1 - 6.7e-05 22.9 0.0 0.0019 18.3 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Zip PF02535.17 CDO69567.1 - 0.27 10.1 8.1 0.27 10.1 5.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Innate_immun PF12782.2 CDO69567.1 - 0.81 8.8 7.9 0.79 8.8 5.5 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family ORMDL PF04061.9 CDO69569.1 - 7e-45 151.9 2.4 9.5e-45 151.5 1.7 1.2 1 0 0 1 1 1 1 ORMDL family Staygreen PF12638.2 CDO69569.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Staygreen protein THF_DHG_CYH PF00763.18 CDO69570.1 - 7.1e-15 55.0 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CDO69570.1 - 8e-11 41.2 0.2 2.1e-10 39.8 0.1 1.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 CDO69570.1 - 0.093 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WD40 PF00400.27 CDO69571.1 - 3.9e-31 105.7 9.6 1.7e-07 30.8 0.0 7.1 7 1 0 7 7 7 6 WD domain, G-beta repeat Arb1 PF09692.5 CDO69572.1 - 1.5e-08 33.9 0.0 1.3e-07 30.8 0.0 2.2 3 0 0 3 3 3 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Cytochrom_c3_2 PF14537.1 CDO69573.1 - 0.15 12.4 1.6 0.55 10.6 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c3 AAA_16 PF13191.1 CDO69574.1 - 4.6e-19 69.1 0.0 1.2e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ORC4_C PF14629.1 CDO69574.1 - 7.5e-11 41.8 0.0 3.4e-07 29.8 0.0 2.2 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 4 C-terminus AAA_5 PF07728.9 CDO69574.1 - 0.00054 19.7 0.0 0.0037 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CDO69574.1 - 0.0023 17.8 0.0 0.01 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CDO69574.1 - 0.0024 17.5 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 CDO69574.1 - 0.0026 17.9 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CDO69574.1 - 0.0062 16.0 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CDO69574.1 - 0.0063 16.6 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO69574.1 - 0.0076 15.9 0.0 0.025 14.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain PduV-EutP PF10662.4 CDO69574.1 - 0.14 11.6 0.0 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AT_hook PF02178.14 CDO69574.1 - 3.6 7.5 9.8 0.085 12.5 1.4 2.6 2 0 0 2 2 2 0 AT hook motif DivIC PF04977.10 CDO69575.1 - 4.6 6.7 23.4 0.57 9.7 1.5 4.9 3 2 3 6 6 6 0 Septum formation initiator adh_short PF00106.20 CDO69576.1 - 1.3e-24 86.9 1.4 8.2e-24 84.3 1.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO69576.1 - 1.1e-19 71.1 0.1 2.3e-19 70.1 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO69576.1 - 6.6e-11 42.2 0.9 2.5e-10 40.2 0.1 2.0 1 1 1 2 2 2 1 KR domain Pyr_redox PF00070.22 CDO69576.1 - 2.7e-05 24.4 0.6 0.00069 19.9 0.3 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.16 CDO69576.1 - 0.00026 20.4 0.4 0.00059 19.3 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 CDO69576.1 - 0.0012 18.5 0.1 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CDO69576.1 - 0.0065 16.4 0.8 0.028 14.4 0.5 2.2 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 CDO69576.1 - 0.0098 15.4 0.1 0.088 12.3 0.0 2.1 1 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CDO69576.1 - 0.015 14.9 0.1 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_tran_WecB PF03808.8 CDO69576.1 - 0.016 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family ApbA PF02558.11 CDO69576.1 - 0.031 13.7 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA YjeF_N PF03853.10 CDO69576.1 - 0.091 12.3 0.1 0.22 11.1 0.1 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF1776 PF08643.5 CDO69576.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) eIF2A PF08662.6 CDO69577.1 - 1.8e-42 145.2 0.7 4.2e-39 134.2 0.0 4.7 3 3 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CDO69577.1 - 1.7e-09 37.1 0.0 4.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO69577.1 - 5.3e-07 29.5 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CDO69577.1 - 1.8e-06 27.5 0.4 9.7 6.2 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat RRM_5 PF13893.1 CDO69577.1 - 0.00041 20.1 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) P4Ha_N PF08336.6 CDO69577.1 - 0.55 10.0 3.8 1.1 9.1 2.6 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region RRM_1 PF00076.17 CDO69578.1 - 1.1e-32 111.4 0.0 6.5e-16 57.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO69578.1 - 3.9e-18 65.1 0.0 1.5e-09 37.6 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO69578.1 - 4.3e-13 48.9 0.0 5.7e-09 35.7 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CDO69578.1 - 1.2e-05 25.1 0.0 3.7e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 CDO69578.1 - 0.00045 19.9 0.0 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RasGAP PF00616.14 CDO69579.1 - 2.3e-33 115.5 0.0 3.9e-32 111.5 0.0 2.6 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 CDO69579.1 - 1.4e-06 28.2 0.0 3.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.1 CDO69579.1 - 3.3e-05 23.7 0.1 0.00013 21.8 0.0 2.1 1 0 0 1 1 1 1 Cell morphogenesis C-terminal Band_7 PF01145.20 CDO69580.1 - 1.5e-22 80.4 3.6 2.3e-22 79.7 2.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.20 CDO69581.1 - 3.3e-22 78.9 0.0 5.2e-21 74.9 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69581.1 - 9.8e-08 31.3 0.0 5.4e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO69581.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family P2 PF07194.6 CDO69581.1 - 0.015 15.1 1.5 0.031 14.1 1.1 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain UCH PF00443.24 CDO69582.1 - 2.3e-28 99.0 0.0 6.8e-28 97.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDO69582.1 - 1.5e-08 34.4 0.3 3.5e-08 33.2 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ELO PF01151.13 CDO69582.1 - 0.27 10.4 2.1 0.44 9.7 1.5 1.3 1 0 0 1 1 1 0 GNS1/SUR4 family BTB PF00651.26 CDO69583.1 - 1.4e-11 44.3 0.0 2.4e-05 24.2 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain Aldedh PF00171.17 CDO69585.1 - 3.5e-105 352.0 0.0 4.2e-105 351.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Rbsn PF11464.3 CDO69585.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Pro_isomerase PF00160.16 CDO69586.1 - 2.9e-38 131.5 0.0 4.2e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CDO69586.1 - 4.2e-16 58.3 0.0 8.1e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO69586.1 - 3.8e-12 45.9 0.0 8.7e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.26 CDO69586.1 - 1.7e-09 37.6 0.0 3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain RRM_5 PF13893.1 CDO69586.1 - 4.6e-09 35.9 0.0 1.2e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3072 PF11272.3 CDO69587.1 - 0.071 12.7 0.1 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) RRP7 PF12923.2 CDO69588.1 - 2e-20 73.1 1.8 2e-20 73.1 1.3 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 CDO69588.1 - 4.6e-06 26.1 0.0 0.00016 21.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO69588.1 - 1.6e-05 24.7 0.0 0.0012 18.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3602 PF12223.3 CDO69588.1 - 0.15 12.4 2.4 1.1 9.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) CDC45 PF02724.9 CDO69588.1 - 6.8 4.5 7.6 17 3.2 5.3 1.7 1 1 0 1 1 1 0 CDC45-like protein WWbp PF10349.4 CDO69590.1 - 0.019 15.8 2.1 0.047 14.5 1.4 1.7 1 1 0 1 1 1 0 WW-domain ligand protein Pro-kuma_activ PF09286.6 CDO69591.1 - 3.1e-37 127.8 0.0 8.7e-37 126.3 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO69591.1 - 0.0025 16.9 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Abhydrolase_6 PF12697.2 CDO69593.1 - 8.7e-35 120.6 0.7 1.1e-34 120.2 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO69593.1 - 1.3e-20 73.6 0.1 2.2e-20 72.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO69593.1 - 5.6e-20 71.8 0.3 4.5e-19 68.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CDO69593.1 - 9.5e-07 28.5 0.0 3.3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase DLH PF01738.13 CDO69593.1 - 3.2e-06 26.5 0.1 0.00047 19.5 0.2 2.9 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 CDO69593.1 - 1.6e-05 24.7 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein DUF2048 PF09752.4 CDO69593.1 - 0.00013 20.9 0.4 0.27 10.0 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2048) Abhydrolase_3 PF07859.8 CDO69593.1 - 0.00082 19.0 0.0 0.0017 17.9 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_2 PF01674.13 CDO69593.1 - 0.002 17.5 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) Ndr PF03096.9 CDO69593.1 - 0.041 12.3 0.0 0.097 11.1 0.0 1.5 2 0 0 2 2 2 0 Ndr family BAAT_C PF08840.6 CDO69593.1 - 0.042 13.5 0.0 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.7 CDO69593.1 - 0.072 11.6 0.2 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 UPF0227 PF05728.7 CDO69593.1 - 0.17 11.6 0.0 6.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) ATG22 PF11700.3 CDO69596.1 - 8.4e-102 341.1 19.2 1.1e-101 340.7 13.3 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 CDO69596.1 - 1.2e-12 47.2 33.1 2.6e-08 33.0 8.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SHOCT PF09851.4 CDO69596.1 - 0.0021 17.4 2.7 0.0034 16.8 1.8 1.3 1 0 0 1 1 1 1 Short C-terminal domain Pkinase PF00069.20 CDO69599.1 - 0.077 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 CDO69600.1 - 0.00077 18.6 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Gryzun PF07919.7 CDO69602.1 - 3.6e-55 187.3 0.0 5.1e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 CDO69602.1 - 2.6e-40 138.4 0.8 1.9e-38 132.3 0.5 2.5 1 1 0 1 1 1 1 Foie gras liver health family 1 TPR_12 PF13424.1 CDO69602.1 - 2.1e-05 24.3 0.3 0.0061 16.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Gryzun-like PF12742.2 CDO69602.1 - 0.0019 17.9 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Trs65 PF12735.2 CDO69602.1 - 0.01 15.1 0.0 1.8 7.8 0.0 2.6 2 0 0 2 2 2 0 TRAPP trafficking subunit Trs65 TPR_1 PF00515.23 CDO69602.1 - 0.01 15.4 0.0 0.044 13.4 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TRAPPC10 PF12584.3 CDO69602.1 - 0.05 13.1 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_2 PF07719.12 CDO69602.1 - 0.072 13.0 3.8 0.11 12.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDO69602.1 - 0.12 12.2 0.1 0.64 9.9 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF960 PF06124.6 CDO69602.1 - 0.16 12.2 0.0 0.71 10.1 0.0 2.1 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) TPR_8 PF13181.1 CDO69602.1 - 0.26 11.1 0.6 0.94 9.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Amidase PF01425.16 CDO69603.1 - 3e-33 115.3 0.3 4.5e-33 114.7 0.2 1.1 1 0 0 1 1 1 1 Amidase Acetyltransf_1 PF00583.19 CDO69606.1 - 3.1e-07 30.3 0.1 4.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CDO69606.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CDO69606.1 - 0.0022 18.1 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO69606.1 - 0.0046 16.6 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 CDO69606.1 - 0.081 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cyclin PF08613.6 CDO69607.1 - 7.6e-08 32.8 0.0 9.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CDO69607.1 - 3e-07 30.0 0.0 4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribonucleas_3_3 PF14622.1 CDO69612.1 - 0.00018 21.4 0.1 0.0013 18.6 0.1 1.9 1 1 0 1 1 1 1 Ribonuclease-III-like RVT_1 PF00078.22 CDO69613.1 - 1e-20 74.0 0.1 2.8e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CDO69613.1 - 1.5e-15 56.5 0.3 3.8e-15 55.2 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 CDO69613.1 - 7.1e-09 36.0 0.1 1.6e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CDO69613.1 - 2.1e-07 30.9 0.0 3.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDO69613.1 - 2e-05 24.1 0.0 4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO69613.1 - 0.00014 21.6 0.0 0.00046 19.9 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease rve PF00665.21 CDO69613.1 - 0.0013 18.8 0.0 0.039 14.0 0.0 3.0 1 1 0 1 1 1 1 Integrase core domain RVP PF00077.15 CDO69613.1 - 0.02 14.7 0.1 0.055 13.3 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease SF3a60_bindingd PF12108.3 CDO69613.1 - 0.39 10.2 4.4 8 6.0 0.1 3.2 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain UBN2_2 PF14227.1 CDO69614.1 - 2.8e-13 49.4 0.0 6.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO69614.1 - 1.3e-12 47.5 0.0 2.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO69614.1 - 0.001 18.9 3.4 0.001 18.9 2.3 2.1 2 0 0 2 2 2 1 Zinc knuckle rve PF00665.21 CDO69615.1 - 4.9e-06 26.6 0.1 6.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 CDO69616.1 - 5.3e-83 277.7 0.0 7.2e-83 277.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO69616.1 - 0.036 14.1 0.2 7.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain DDE_3 PF13358.1 CDO69617.1 - 5.2e-18 65.1 0.0 1.2e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CDO69617.1 - 1.1e-06 28.5 0.0 4.6e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Transposase rve PF00665.21 CDO69617.1 - 0.027 14.5 0.0 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain Methyltransf_11 PF08241.7 CDO69617.1 - 0.042 14.3 0.2 1 9.9 0.0 3.1 4 1 0 4 4 4 0 Methyltransferase domain zinc_ribbon_6 PF14599.1 CDO69618.1 - 0.019 14.7 0.7 0.046 13.5 0.5 1.8 1 1 0 1 1 1 0 Zinc-ribbon Ribosomal_S27e PF01667.12 CDO69618.1 - 0.029 13.8 0.6 0.076 12.5 0.2 1.7 2 0 0 2 2 2 0 Ribosomal protein S27 DUF2015 PF09435.5 CDO69619.1 - 4.6e-32 110.4 0.0 5.1e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) RAG1 PF12940.2 CDO69619.1 - 0.07 11.4 0.0 0.077 11.3 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1) Epimerase PF01370.16 CDO69620.1 - 4.3e-18 65.6 0.0 6.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO69620.1 - 1.2e-13 50.4 0.0 1.7e-13 49.9 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CDO69620.1 - 1.2e-11 44.0 0.0 6.2e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 CDO69620.1 - 1.8e-11 44.3 0.4 3.3e-11 43.5 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CDO69620.1 - 1e-05 25.4 1.9 1.7e-05 24.8 0.4 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 CDO69620.1 - 1.7e-05 24.2 0.1 2.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 CDO69620.1 - 0.00035 20.2 0.1 0.0052 16.4 0.0 2.3 2 0 0 2 2 2 1 KR domain F-box PF00646.28 CDO69621.1 - 1.1e-05 24.9 0.1 2.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 CDO69621.1 - 6.9e-05 22.6 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain F-box-like PF12937.2 CDO69621.1 - 0.00079 19.1 0.1 0.0019 17.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.12 CDO69621.1 - 0.007 16.2 0.2 0.026 14.4 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDO69621.1 - 0.0087 16.7 0.7 0.027 15.1 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDO69621.1 - 0.01 16.3 0.6 0.062 13.9 0.4 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 CDO69621.1 - 0.013 15.1 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 TPR repeat TPR_1 PF00515.23 CDO69621.1 - 0.028 14.0 0.1 0.071 12.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Rapamycin_bind PF08771.6 CDO69621.1 - 0.029 14.4 0.0 0.45 10.6 0.0 2.5 2 0 0 2 2 2 0 Rapamycin binding domain PhoU PF01895.14 CDO69621.1 - 0.14 12.6 0.1 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoU domain TPR_7 PF13176.1 CDO69621.1 - 1.1 9.2 5.0 1.1 9.1 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.26 CDO69622.1 - 3e-26 90.9 1.0 3e-26 90.9 0.7 1.7 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.6 CDO69622.1 - 4.3e-16 59.0 0.1 1.3e-15 57.5 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.12 CDO69622.1 - 0.07 13.0 0.1 0.33 10.9 0.0 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.27 CDO69623.1 - 4e-10 39.1 2.3 1.2 9.0 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat RED_N PF07808.8 CDO69627.1 - 4.5e-19 68.6 3.2 4.5e-19 68.6 2.2 2.2 3 0 0 3 3 3 1 RED-like protein N-terminal region IF4E PF01652.13 CDO69629.1 - 1.6e-48 164.3 0.0 2.3e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Kei1 PF08552.6 CDO69630.1 - 3.4e-37 127.9 3.5 4.7e-37 127.4 2.4 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4199 PF13858.1 CDO69630.1 - 0.0027 17.6 3.0 0.0046 16.9 2.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4199) FixQ PF05545.6 CDO69630.1 - 0.19 11.3 2.1 0.22 11.1 0.1 2.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ ACPS PF01648.15 CDO69631.1 - 0.0008 19.2 0.0 0.00092 19.0 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF3436 PF11918.3 CDO69632.1 - 0.028 14.6 0.4 0.11 12.8 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3436) PQ-loop PF04193.9 CDO69633.1 - 2.6e-33 113.3 5.3 5e-18 64.4 0.2 3.0 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.13 CDO69633.1 - 0.0037 17.7 3.5 0.0048 17.3 0.4 2.2 1 1 0 2 2 2 1 ER lumen protein retaining receptor MtN3_slv PF03083.11 CDO69633.1 - 0.0093 15.8 7.7 0.8 9.6 0.3 2.8 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange DUF3087 PF11286.3 CDO69633.1 - 0.049 12.8 0.1 0.11 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) YrhC PF14143.1 CDO69633.1 - 0.74 9.7 3.6 1.3 9.0 0.0 2.7 2 1 1 3 3 3 0 YrhC-like protein Clr2 PF10383.4 CDO69634.1 - 0.0053 16.7 0.0 0.083 12.8 0.0 2.4 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 KAR9 PF08580.5 CDO69635.1 - 2.6e-07 29.3 64.0 1.3e-06 27.0 34.4 4.4 3 1 0 3 3 3 2 Yeast cortical protein KAR9 Muted PF14942.1 CDO69635.1 - 0.0084 15.9 1.0 0.04 13.7 0.3 2.3 1 1 1 2 2 2 1 Organelle biogenesis, Muted-like protein Myb_DNA-bind_5 PF13873.1 CDO69635.1 - 0.073 12.9 0.4 0.25 11.2 0.3 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain IncA PF04156.9 CDO69635.1 - 0.95 9.0 6.1 0.34 10.4 1.8 2.0 2 0 0 2 2 2 0 IncA protein TPR_16 PF13432.1 CDO69636.1 - 2e-09 37.8 1.1 2e-09 37.8 0.8 3.2 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CDO69636.1 - 7.4e-09 35.8 2.9 4.7e-08 33.2 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CDO69636.1 - 1.5e-08 34.1 0.9 2.7e-08 33.3 0.1 1.9 2 0 0 2 2 1 1 TPR repeat TPR_17 PF13431.1 CDO69636.1 - 1.8e-06 27.7 0.2 8.5e-06 25.5 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDO69636.1 - 8.1e-06 25.3 2.8 0.0025 17.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDO69636.1 - 1.3e-05 25.4 21.9 0.0026 18.2 0.1 5.1 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDO69636.1 - 0.00011 22.0 0.3 0.00034 20.5 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDO69636.1 - 0.001 18.5 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO69636.1 - 0.0043 16.7 4.5 0.034 13.9 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CDO69636.1 - 0.0062 16.3 0.2 0.0062 16.3 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 CDO69636.1 - 0.0073 16.4 1.1 0.0073 16.4 0.8 2.7 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 CDO69636.1 - 0.0077 16.1 0.6 0.0077 16.1 0.4 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CDO69636.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 CDO69636.1 - 0.029 14.6 0.5 0.029 14.6 0.4 2.3 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_8 PF13181.1 CDO69636.1 - 0.08 12.7 0.1 2.3 8.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 CDO69636.1 - 0.26 11.8 0.1 0.26 11.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDO69636.1 - 1.5 9.4 6.4 2.5 8.7 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat Lactamase_B_2 PF12706.2 CDO69637.1 - 3.3e-21 75.7 1.0 4.6e-21 75.2 0.7 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CDO69637.1 - 3.1e-15 56.2 0.5 5.1e-15 55.5 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MDMPI_C PF07398.6 CDO69637.1 - 1.1 9.8 5.6 20 5.8 1.3 3.2 2 1 1 3 3 3 0 MDMPI C-terminal domain Lactamase_B PF00753.22 CDO69637.1 - 2.5 7.7 10.7 2.2 7.8 4.7 2.6 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily TPT PF03151.11 CDO69638.1 - 4.1e-31 107.7 6.1 4.1e-31 107.7 4.2 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CDO69638.1 - 1.5e-14 53.5 17.9 2.2e-14 53.1 12.4 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CDO69638.1 - 4.4e-08 33.2 34.7 1.4e-06 28.3 8.3 3.7 2 1 1 3 3 3 2 EamA-like transporter family UDPGT PF00201.13 CDO69639.1 - 2.6e-19 69.1 0.1 4.5e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CDO69639.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CDO69639.1 - 0.11 11.6 0.1 0.61 9.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 1 PQ-loop PF04193.9 CDO69640.1 - 1.4e-12 46.9 2.6 1.7e-12 46.6 0.4 2.1 2 1 0 2 2 2 1 PQ loop repeat Shisa PF13908.1 CDO69640.1 - 0.13 12.4 0.7 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF21 PF01595.15 CDO69640.1 - 1.4 8.1 0.0 1.4 8.1 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF21 DUF1771 PF08590.5 CDO69641.1 - 0.00037 20.4 7.9 0.00096 19.1 5.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 CDO69641.1 - 0.0029 17.0 0.6 0.12 11.8 0.0 3.2 4 0 0 4 4 4 1 CUE domain Aldedh PF00171.17 CDO69642.1 - 4.1e-97 325.3 1.1 5.1e-97 325.1 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CDO69642.1 - 0.00022 20.0 0.0 0.00036 19.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Aldedh PF00171.17 CDO69643.1 - 2.1e-92 309.9 5.3 4.4e-78 262.6 1.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 CDO69643.1 - 3e-05 22.9 0.0 4.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Acetyltransf_10 PF13673.1 CDO69644.1 - 3e-05 24.1 0.0 5.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO69644.1 - 5.4e-05 23.1 0.0 9.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDO69644.1 - 7.3e-05 22.8 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NOSIC PF08060.8 CDO69644.1 - 0.038 13.8 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 NOSIC (NUC001) domain SIR2 PF02146.12 CDO69645.1 - 7.7e-45 152.7 0.0 5.7e-44 149.9 0.0 2.3 1 1 0 1 1 1 1 Sir2 family DUF592 PF04574.8 CDO69645.1 - 2.2e-07 30.5 0.1 3.2e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF592) CutC PF03932.9 CDO69645.1 - 0.011 15.0 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 CutC family TPP_enzyme_M PF00205.17 CDO69645.1 - 0.063 13.0 0.2 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF357 PF04010.8 CDO69647.1 - 0.082 12.6 2.5 0.24 11.1 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF357) ATG27 PF09451.5 CDO69647.1 - 0.085 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF445 PF04286.7 CDO69647.1 - 0.28 10.6 12.1 0.023 14.2 1.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF445) Prominin PF05478.6 CDO69647.1 - 2.1 5.7 4.5 0.49 7.8 0.6 1.8 2 0 0 2 2 2 0 Prominin V_ATPase_I PF01496.14 CDO69647.1 - 8.2 4.1 4.7 15 3.2 3.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Chromo PF00385.19 CDO69648.1 - 4e-13 48.8 1.1 1.1e-12 47.4 0.1 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CDO69648.1 - 1.3e-10 40.9 0.2 9.7e-09 34.9 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain MIP-T3 PF10243.4 CDO69648.1 - 0.1 11.0 21.7 0.14 10.5 15.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pox_Ag35 PF03286.9 CDO69648.1 - 1.8 8.0 23.2 0.34 10.4 2.9 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein AT_hook PF02178.14 CDO69648.1 - 3.1 7.7 11.9 0.4 10.4 2.6 3.6 3 0 0 3 3 3 0 AT hook motif RRM_1 PF00076.17 CDO69649.1 - 1.3e-14 53.6 0.0 2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO69649.1 - 1.7e-12 47.1 0.0 2.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO69649.1 - 3e-07 30.1 0.0 4.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CDO69649.1 - 0.0061 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif HMA PF00403.21 CDO69649.1 - 0.04 14.0 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal-associated domain Nup35_RRM_2 PF14605.1 CDO69649.1 - 0.053 13.2 0.1 0.11 12.3 0.1 1.5 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-MYND PF01753.13 CDO69650.1 - 1.1e-05 25.2 10.3 0.00088 19.1 0.8 2.5 2 0 0 2 2 2 2 MYND finger DUF3846 PF12957.2 CDO69650.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) CAP_N PF01213.14 CDO69651.1 - 0.0039 16.5 3.5 0.0056 16.0 2.4 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Pro-kuma_activ PF09286.6 CDO69652.1 - 1.9e-37 128.4 0.0 6.6e-37 126.7 0.0 1.9 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO69652.1 - 3.7e-05 23.0 0.2 3.7e-05 23.0 0.1 2.2 2 1 0 2 2 2 1 Subtilase family DUF1680 PF07944.7 CDO69653.1 - 1.4e-17 63.2 0.0 8.2e-16 57.3 0.0 2.5 2 1 1 3 3 3 2 Putative glycosyl hydrolase of unknown function (DUF1680) Sds3 PF08598.6 CDO69654.1 - 1.2e-06 28.2 1.2 1.9e-06 27.5 0.8 1.4 1 0 0 1 1 1 1 Sds3-like DLH PF01738.13 CDO69655.1 - 2.8e-23 82.3 0.0 3.3e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CDO69655.1 - 3.5e-06 26.8 0.0 4.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO69655.1 - 0.0011 18.8 0.3 0.99 9.2 0.2 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Acyl_transf_2 PF02273.10 CDO69655.1 - 0.0051 15.8 0.0 0.0064 15.5 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase Abhydrolase_1 PF00561.15 CDO69655.1 - 0.058 12.9 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold TPR_2 PF07719.12 CDO69657.1 - 1e-08 34.4 0.0 3.9e-05 23.2 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 CDO69657.1 - 1.9e-08 33.8 0.2 0.0025 17.4 0.0 2.1 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CDO69657.1 - 5.3e-06 25.8 0.1 0.0017 17.9 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO69657.1 - 0.00078 19.7 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDO69657.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 CDO69657.1 - 0.0016 18.9 0.2 0.058 14.0 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO69657.1 - 0.0022 17.6 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDO69657.1 - 0.0061 17.2 0.5 0.086 13.5 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDO69657.1 - 0.0069 16.3 0.1 0.034 14.0 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CDO69657.1 - 0.032 14.3 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CDO69657.1 - 0.063 13.5 0.0 16 5.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CDO69657.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DEAD PF00270.24 CDO69658.1 - 2.8e-45 153.8 0.0 1.1e-44 151.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO69658.1 - 2.2e-27 94.7 0.1 6.2e-27 93.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO69658.1 - 0.0045 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S28e PF01200.13 CDO69658.1 - 0.041 13.6 0.7 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S28e DUF2029 PF09594.5 CDO69659.1 - 0.004 16.6 0.6 0.0064 16.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) PAT1 PF09770.4 CDO69659.1 - 0.32 9.2 53.0 0.42 8.7 36.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF383 PF04063.9 CDO69660.1 - 1e-57 194.7 0.0 5.4e-57 192.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CDO69660.1 - 9.9e-21 73.0 1.0 2.9e-20 71.5 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 CDO69660.1 - 0.015 15.5 0.0 0.92 9.8 0.0 3.2 2 1 0 2 2 2 0 HEAT repeats Proteasom_PSMB PF10508.4 CDO69660.1 - 0.022 13.0 0.7 2 6.5 0.2 2.4 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT PF02985.17 CDO69660.1 - 0.073 13.1 0.0 0.37 11.0 0.0 2.3 1 0 0 1 1 1 0 HEAT repeat RTC4 PF14474.1 CDO69661.1 - 6.9e-23 80.9 0.0 1.6e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain DLH PF01738.13 CDO69663.1 - 2.8e-26 92.1 0.0 3.2e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CDO69663.1 - 6.1e-07 29.3 0.0 8.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO69663.1 - 1.6e-06 28.1 0.1 0.00025 21.0 0.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family PTS_2-RNA PF01885.11 CDO69664.1 - 3.8e-19 68.7 0.1 5e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ribosomal_L23 PF00276.15 CDO69665.1 - 3.5e-11 42.8 0.0 5.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 DLH PF01738.13 CDO69666.1 - 3.8e-23 81.9 0.0 4.4e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CDO69666.1 - 4.3e-05 23.3 0.0 6.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO69666.1 - 0.00077 19.4 1.2 0.016 15.0 0.8 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Prok-E2_E PF14462.1 CDO69666.1 - 0.04 13.5 0.0 0.08 12.5 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family E Zn_clus PF00172.13 CDO69667.1 - 3.8e-09 36.3 10.2 6.8e-09 35.4 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.18 CDO69669.1 - 1.3e-67 228.3 5.1 1.6e-67 228.0 3.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO69669.1 - 8.1e-09 35.6 0.5 4.9e-07 29.8 0.0 3.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Pkinase PF00069.20 CDO69670.1 - 8.3e-26 90.6 0.0 6.9e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69670.1 - 4.1e-07 29.3 0.0 0.0097 15.0 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Methyltransf_16 PF10294.4 CDO69672.1 - 3.4e-28 98.2 0.0 4.8e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CDO69672.1 - 0.0036 17.0 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO69672.1 - 0.087 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CDO69672.1 - 0.15 11.4 0.0 0.46 9.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Rhomboid PF01694.17 CDO69673.1 - 1.2e-16 60.9 13.7 4.7e-14 52.6 9.5 2.9 1 1 0 1 1 1 1 Rhomboid family SHS2_Rpb7-N PF03876.12 CDO69674.1 - 1.1e-15 57.4 0.0 1.8e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CDO69674.1 - 1.1e-11 44.6 0.2 2.2e-11 43.6 0.2 1.5 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 CDO69674.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.5 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 adh_short_C2 PF13561.1 CDO69675.1 - 8e-34 117.4 0.0 9.5e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO69675.1 - 1.3e-29 103.2 0.4 1.7e-29 102.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO69675.1 - 5e-13 49.0 0.2 1.8e-12 47.3 0.2 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 CDO69675.1 - 8e-06 25.4 0.3 1.8e-05 24.3 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CDO69675.1 - 0.00015 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) AdoHcyase_NAD PF00670.16 CDO69675.1 - 0.0042 16.9 0.1 0.0062 16.3 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Flavodoxin_1 PF00258.20 CDO69675.1 - 0.0078 16.2 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin Polysacc_synt_2 PF02719.10 CDO69675.1 - 0.0089 14.9 0.3 0.011 14.7 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.10 CDO69675.1 - 0.024 14.2 0.1 0.12 12.0 0.1 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.14 CDO69675.1 - 0.055 12.5 1.1 0.089 11.8 0.7 1.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2761 PF10959.3 CDO69675.1 - 0.14 11.7 0.0 0.77 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2761) BNR PF02012.15 CDO69676.1 - 9.6e-12 42.8 33.6 0.99 9.4 0.3 11.7 11 0 0 11 11 11 7 BNR/Asp-box repeat BNR_2 PF13088.1 CDO69676.1 - 4.2e-06 26.2 1.7 1.4 8.1 0.0 5.7 6 0 0 6 6 6 2 BNR repeat-like domain PSII_BNR PF14870.1 CDO69676.1 - 0.0067 15.4 0.8 2.7 6.8 0.0 3.6 3 2 0 3 3 3 2 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.11 CDO69676.1 - 0.022 14.3 1.0 11 5.7 0.1 5.3 6 1 0 6 6 6 0 Mo-co oxidoreductase dimerisation domain Fe_dep_repr_C PF02742.10 CDO69676.1 - 0.053 13.2 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Pro-kuma_activ PF09286.6 CDO69677.1 - 3.5e-34 117.9 0.0 5.5e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO69677.1 - 2.1e-08 33.6 0.5 2.8e-08 33.2 0.3 1.2 1 0 0 1 1 1 1 Subtilase family Ran_BP1 PF00638.13 CDO69678.1 - 2e-17 63.3 0.0 3.5e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Rxt3 PF08642.5 CDO69680.1 - 2e-05 24.8 0.3 0.00011 22.3 0.0 2.4 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 DUF3450 PF11932.3 CDO69681.1 - 0.00036 19.8 0.3 0.0014 17.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.17 CDO69681.1 - 0.0012 18.8 14.4 0.89 9.6 1.4 4.5 3 1 1 4 4 4 2 Seryl-tRNA synthetase N-terminal domain DUF2730 PF10805.3 CDO69681.1 - 0.0013 18.4 4.2 0.049 13.3 0.2 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2730) APG6 PF04111.7 CDO69681.1 - 0.0019 17.3 4.9 0.048 12.7 0.8 2.8 3 0 0 3 3 3 1 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 CDO69681.1 - 0.002 18.0 10.3 0.018 14.8 2.1 3.0 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 CDO69681.1 - 0.004 15.6 0.9 0.004 15.6 0.7 2.1 2 0 0 2 2 2 1 AAA domain NPV_P10 PF05531.7 CDO69681.1 - 0.0064 16.7 11.8 2.6 8.3 1.2 4.7 3 3 1 4 4 4 1 Nucleopolyhedrovirus P10 protein DUF869 PF05911.6 CDO69681.1 - 0.0074 14.5 9.9 0.073 11.3 6.7 1.9 1 1 0 1 1 1 1 Plant protein of unknown function (DUF869) EzrA PF06160.7 CDO69681.1 - 0.0085 14.3 5.9 0.38 8.8 0.1 3.1 3 0 0 3 3 3 1 Septation ring formation regulator, EzrA Filament PF00038.16 CDO69681.1 - 0.013 14.9 7.9 0.15 11.5 0.3 3.2 3 0 0 3 3 3 0 Intermediate filament protein DUF4618 PF15397.1 CDO69681.1 - 0.013 14.8 3.2 0.13 11.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) CCDC155 PF14662.1 CDO69681.1 - 0.014 14.9 3.8 0.014 14.9 2.7 2.7 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 IncA PF04156.9 CDO69681.1 - 0.023 14.3 9.7 0.034 13.7 0.3 3.1 3 1 0 3 3 3 0 IncA protein HAUS-augmin3 PF14932.1 CDO69681.1 - 0.027 13.6 2.7 1 8.4 0.0 2.9 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 DUF2383 PF09537.5 CDO69681.1 - 0.044 14.0 1.3 0.68 10.1 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF2383) Spc24 PF08286.6 CDO69681.1 - 0.073 12.7 5.6 4.3 7.0 0.0 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 NRN1 PF15056.1 CDO69681.1 - 0.089 12.7 0.2 3 7.8 0.0 2.6 2 0 0 2 2 2 0 Neuritin protein family TPR_MLP1_2 PF07926.7 CDO69681.1 - 0.098 12.4 9.5 0.093 12.4 3.3 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 CDO69681.1 - 0.12 12.1 9.1 0.12 12.1 1.1 3.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 CDO69681.1 - 0.14 12.3 11.4 0.31 11.1 1.2 3.8 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBPIP PF07106.8 CDO69681.1 - 0.14 11.6 13.4 2.1 7.8 2.7 3.4 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) LPP PF04728.8 CDO69681.1 - 0.15 11.8 0.3 0.15 11.8 0.2 3.7 5 0 0 5 5 3 0 Lipoprotein leucine-zipper Apolipoprotein PF01442.13 CDO69681.1 - 0.17 11.3 8.9 1.4 8.3 1.5 3.5 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF3782 PF12644.2 CDO69681.1 - 0.21 11.4 3.1 0.28 10.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) USP8_interact PF08941.5 CDO69681.1 - 0.21 10.8 1.0 0.47 9.7 0.1 2.1 2 0 0 2 2 2 0 USP8 interacting DUF948 PF06103.6 CDO69681.1 - 0.23 11.3 12.1 6.1 6.7 0.8 3.8 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 CDO69681.1 - 0.28 10.9 13.8 3.4 7.4 0.1 3.8 3 2 0 3 3 3 0 Laminin Domain II Bacillus_HBL PF05791.6 CDO69681.1 - 0.96 8.7 8.8 1.8 7.8 0.9 2.7 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2353 PF09789.4 CDO69681.1 - 1 8.5 10.6 0.56 9.4 4.1 2.5 2 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Rootletin PF15035.1 CDO69681.1 - 1.3 8.9 14.0 8.5 6.3 0.1 4.1 3 2 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion Retrotrans_gag PF03732.12 CDO69681.1 - 1.5 8.8 5.1 16 5.6 0.0 3.6 2 2 1 3 3 3 0 Retrotransposon gag protein Phage_GP20 PF06810.6 CDO69681.1 - 1.6 8.1 11.4 0.78 9.1 0.5 3.7 3 1 0 3 3 3 0 Phage minor structural protein GP20 FlxA PF14282.1 CDO69681.1 - 1.8 8.5 9.6 2.4 8.1 0.4 3.8 4 0 0 4 4 4 0 FlxA-like protein Snapin_Pallidin PF14712.1 CDO69681.1 - 2.1 8.7 11.3 3.8 7.8 1.8 3.7 3 2 1 4 4 4 0 Snapin/Pallidin DUF3847 PF12958.2 CDO69681.1 - 2.9 7.7 7.1 1.8 8.3 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) ApoLp-III PF07464.6 CDO69681.1 - 3.5 7.6 11.4 0.1 12.6 0.4 3.2 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF4140 PF13600.1 CDO69681.1 - 3.9 7.9 10.4 3.3 8.2 0.3 3.7 4 0 0 4 4 3 0 N-terminal domain of unknown function (DUF4140) Mod_r PF07200.8 CDO69681.1 - 9.2 6.1 13.5 1.4 8.8 0.5 3.9 3 2 2 5 5 5 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.7 CDO69682.1 - 0.022 14.5 2.6 18 5.1 0.0 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) NEMO PF11577.3 CDO69682.1 - 0.049 13.3 1.9 0.33 10.7 0.0 2.4 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Bacillus_HBL PF05791.6 CDO69682.1 - 0.11 11.8 1.0 1.6 8.0 0.0 2.7 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) MIP-T3 PF10243.4 CDO69685.1 - 1.8 6.9 4.8 1.7 7.0 3.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HSF_DNA-bind PF00447.12 CDO69686.1 - 1.5e-35 121.4 1.5 2.7e-35 120.6 1.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Vezatin PF12632.2 CDO69688.1 - 0.00045 19.3 0.5 0.00094 18.3 0.3 1.5 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes LisH PF08513.6 CDO69689.1 - 0.00031 20.3 0.1 0.00052 19.6 0.1 1.4 1 0 0 1 1 1 1 LisH Ycf1 PF05758.7 CDO69689.1 - 3.1 5.4 7.8 5.2 4.6 5.4 1.2 1 0 0 1 1 1 0 Ycf1 NARP1 PF12569.3 CDO69689.1 - 4.1 6.0 11.1 9.3 4.8 7.7 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 START PF01852.14 CDO69690.1 - 1.9e-20 73.1 0.2 1.7e-10 40.5 0.0 3.7 4 0 0 4 4 4 3 START domain Phos_pyr_kin PF08543.7 CDO69691.1 - 3.6e-12 46.0 0.0 8.7e-12 44.7 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CDO69691.1 - 5.7e-05 22.3 0.0 5.7e-05 22.3 0.0 2.6 3 0 0 3 3 3 1 pfkB family carbohydrate kinase Nitrate_red_gam PF02665.9 CDO69692.1 - 0.074 12.3 0.1 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Adeno_E3_CR2 PF02439.10 CDO69693.1 - 0.068 12.7 1.6 0.11 12.0 1.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Plasmodium_Vir PF05795.6 CDO69693.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein VSP PF03302.8 CDO69693.1 - 0.19 10.3 0.4 0.25 9.9 0.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein FUSC_2 PF13515.1 CDO69695.1 - 1.1e-16 60.9 8.8 1.1e-16 60.9 6.1 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 CDO69695.1 - 2.1e-09 37.3 0.2 1.5e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 CDO69695.1 - 6.1e-08 31.7 10.3 4.2e-05 22.3 4.4 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 CDO69695.1 - 3.5e-07 29.0 16.7 4.3e-06 25.4 5.2 2.8 2 1 0 2 2 2 2 Fusaric acid resistance protein family SAB PF04382.8 CDO69695.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 SAB domain Cu-oxidase PF00394.17 CDO69696.1 - 7.2e-50 168.9 0.1 1e-45 155.4 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CDO69696.1 - 2e-40 137.2 2.8 3.4e-36 123.5 0.1 3.6 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 CDO69696.1 - 3.5e-38 130.2 6.5 5.8e-34 116.5 0.1 4.0 3 1 0 3 3 3 3 Multicopper oxidase RNA_pol_Rbc25 PF08292.7 CDO69697.1 - 9.2e-32 109.8 0.0 1.1e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Mito_carr PF00153.22 CDO69698.1 - 3.3e-50 167.7 1.3 1.4e-23 82.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ldr_toxin PF13940.1 CDO69698.1 - 1.6 8.5 4.7 2.1 8.2 1.7 2.2 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system Actin PF00022.14 CDO69699.1 - 6.6e-121 403.4 0.0 8.1e-121 403.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CDO69699.1 - 0.0054 15.3 0.0 0.015 13.9 0.0 1.6 1 1 0 1 1 1 1 MreB/Mbl protein zf-HC5HC2H_2 PF13832.1 CDO69700.1 - 6e-31 106.7 9.7 3.2e-30 104.3 3.6 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 CDO69700.1 - 5e-23 82.1 1.8 5e-23 82.1 1.3 3.0 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 CDO69700.1 - 2.5e-21 75.5 8.9 3.6e-21 75.1 2.0 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 CDO69700.1 - 2.5e-20 72.1 0.1 4.7e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 CDO69700.1 - 1.9e-16 59.0 8.5 3.7e-15 54.9 1.9 2.5 2 0 0 2 2 2 2 PHD-finger PWWP PF00855.12 CDO69700.1 - 7.9e-13 48.4 0.3 2.4e-12 46.8 0.2 1.8 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 CDO69700.1 - 7.9e-10 38.2 16.9 1.4e-09 37.4 4.0 2.8 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 CDO69700.1 - 0.0054 16.0 1.0 0.0054 16.0 0.7 2.3 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 CDO69700.1 - 0.0097 15.6 0.2 0.0097 15.6 0.1 2.5 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 CDO69700.1 - 0.011 15.6 0.5 0.011 15.6 0.3 2.8 4 0 0 4 4 4 0 FYVE-type zinc finger Prok-RING_1 PF14446.1 CDO69700.1 - 8.4 6.2 13.9 0.47 10.2 1.5 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DNA_pol_delta_4 PF04081.8 CDO69701.1 - 7.4e-24 84.4 0.1 1.2e-23 83.7 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Gp_dh_C PF02800.15 CDO69701.1 - 0.026 13.9 0.3 0.062 12.7 0.2 1.7 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Ocular_alb PF02101.10 CDO69701.1 - 0.22 10.1 0.3 0.3 9.6 0.2 1.1 1 0 0 1 1 1 0 Ocular albinism type 1 protein Mt_ATP-synt_B PF05405.9 CDO69702.1 - 1.1e-44 151.8 10.6 1.3e-44 151.5 7.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3773 PF12608.3 CDO69702.1 - 0.042 13.8 0.3 0.067 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3773) SpoIIID PF12116.3 CDO69702.1 - 0.55 10.1 3.2 8.9 6.3 0.1 3.0 2 1 1 3 3 3 0 Stage III sporulation protein D DASH_Duo1 PF08651.5 CDO69702.1 - 6.8 6.3 7.3 32 4.2 1.6 3.1 2 1 1 3 3 3 0 DASH complex subunit Duo1 Methyltransf_16 PF10294.4 CDO69703.1 - 5.1e-14 52.1 0.0 1.1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CDO69703.1 - 1.2e-05 25.8 0.0 4.1e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO69703.1 - 0.0071 16.3 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDO69703.1 - 0.0087 15.4 0.0 0.092 12.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CDO69703.1 - 0.031 14.7 0.0 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 CDO69703.1 - 0.04 14.4 0.0 0.34 11.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 CDO69703.1 - 0.052 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CDO69703.1 - 0.16 11.5 0.0 0.39 10.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Lipase_GDSL PF00657.17 CDO69704.1 - 1e-07 32.0 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CDO69704.1 - 6.7e-05 23.0 0.0 8.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Methyltransf_25 PF13649.1 CDO69705.1 - 0.00096 19.4 0.0 0.0038 17.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO69705.1 - 0.0011 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain LRR_2 PF07723.8 CDO69706.1 - 0.043 14.3 0.0 13 6.4 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat DPPIV_N PF00930.16 CDO69707.1 - 3.7e-70 236.2 0.1 5.6e-70 235.6 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CDO69707.1 - 2.8e-48 163.9 0.8 4.3e-48 163.3 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDO69707.1 - 6.8e-09 35.6 0.2 1.3e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO69707.1 - 6.4e-07 29.4 1.0 3.2e-06 27.1 0.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CDO69707.1 - 2.2e-06 27.3 2.8 5.8e-06 25.9 1.4 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 CDO69707.1 - 0.034 13.7 0.0 0.091 12.3 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CDO69707.1 - 0.091 12.1 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF998 PF06197.8 CDO69708.1 - 0.028 13.7 0.7 0.041 13.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Dynamin_M PF01031.15 CDO69709.1 - 1.8e-95 319.1 0.0 3.7e-95 318.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CDO69709.1 - 8e-54 181.9 0.0 1.5e-53 181.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CDO69709.1 - 2.1e-30 104.4 1.7 5.3e-29 99.9 0.7 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CDO69709.1 - 0.0051 16.7 0.0 0.064 13.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.24 CDO69710.1 - 1.2e-14 54.6 0.0 3.1e-13 50.0 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 CDO69710.1 - 5.8e-07 29.3 0.1 5.8e-07 29.3 0.1 2.7 2 1 0 2 2 2 1 BCS1 N terminal AAA_33 PF13671.1 CDO69710.1 - 0.00094 19.0 0.7 0.0027 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CDO69710.1 - 0.00097 19.9 4.6 0.008 16.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CDO69710.1 - 0.0014 18.6 2.0 0.0022 17.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 CDO69710.1 - 0.0088 15.5 1.8 0.0097 15.4 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 CDO69710.1 - 0.01 15.4 7.4 0.047 13.2 5.1 2.0 1 1 0 1 1 1 0 AAA domain DDRGK PF09756.4 CDO69710.1 - 0.046 13.1 17.0 11 5.4 14.9 2.4 2 0 0 2 2 2 0 DDRGK domain RuvB_N PF05496.7 CDO69710.1 - 0.055 12.5 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CDO69710.1 - 0.066 12.9 0.5 0.35 10.6 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain AAA_22 PF13401.1 CDO69710.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CDO69710.1 - 0.11 12.1 0.1 0.34 10.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_3 PF07726.6 CDO69710.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PQQ PF01011.16 CDO69710.1 - 0.16 11.5 0.1 0.39 10.3 0.1 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat AAA_18 PF13238.1 CDO69710.1 - 0.34 11.2 0.1 0.34 11.2 0.1 3.1 3 0 0 3 3 3 0 AAA domain MIP-T3 PF10243.4 CDO69710.1 - 2.1 6.7 33.6 4.4 5.6 23.3 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SYS1 PF09801.4 CDO69711.1 - 2.1e-20 73.1 2.0 3.4e-18 66.0 1.2 2.0 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network zf-MYND PF01753.13 CDO69713.1 - 0.00029 20.6 11.2 0.00058 19.6 7.7 1.5 1 0 0 1 1 1 1 MYND finger AAA_2 PF07724.9 CDO69714.1 - 3.3e-46 157.3 0.0 9.5e-44 149.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CDO69714.1 - 2e-20 73.3 1.1 7.2e-11 42.4 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CDO69714.1 - 3.4e-18 65.3 0.2 3.4e-18 65.3 0.1 2.5 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CDO69714.1 - 1.2e-16 60.6 0.0 8.5e-11 41.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDO69714.1 - 1.5e-12 47.9 5.7 0.0001 22.3 0.0 4.6 3 2 1 4 4 4 2 AAA ATPase domain DnaJ PF00226.26 CDO69714.1 - 5.1e-10 38.9 0.0 1.5e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain AAA_22 PF13401.1 CDO69714.1 - 6.3e-10 39.3 1.0 0.0021 18.2 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 CDO69714.1 - 1.9e-08 35.1 1.9 0.0053 17.5 0.0 3.7 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CDO69714.1 - 9e-08 31.7 0.0 4.8e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CDO69714.1 - 2.8e-07 30.1 0.7 0.021 14.2 0.0 3.4 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_28 PF13521.1 CDO69714.1 - 6.6e-07 29.4 0.2 0.2 11.5 0.0 5.1 4 2 0 4 4 4 2 AAA domain AAA_14 PF13173.1 CDO69714.1 - 8.8e-07 28.8 0.0 0.0098 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 CDO69714.1 - 5.6e-06 25.6 0.1 0.17 11.0 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CDO69714.1 - 2.3e-05 24.0 0.0 0.026 14.2 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 CDO69714.1 - 3e-05 24.3 7.5 0.052 13.8 0.0 3.7 4 0 0 4 4 3 2 AAA domain Arch_ATPase PF01637.13 CDO69714.1 - 8.1e-05 22.4 10.1 0.0097 15.6 0.3 4.6 3 2 0 3 3 3 1 Archaeal ATPase ABC_tran PF00005.22 CDO69714.1 - 0.00011 22.5 5.0 0.16 12.3 0.0 3.9 3 1 0 3 3 3 1 ABC transporter AAA_25 PF13481.1 CDO69714.1 - 0.00032 20.1 1.7 1 8.6 0.0 4.3 6 1 0 6 6 3 1 AAA domain RuvB_N PF05496.7 CDO69714.1 - 0.00035 19.7 2.1 0.71 8.8 0.0 3.3 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 CDO69714.1 - 0.00039 20.1 0.0 0.17 11.5 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CDO69714.1 - 0.00039 20.5 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.1 CDO69714.1 - 0.00043 19.9 0.0 0.22 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CDO69714.1 - 0.0019 18.5 20.7 0.011 16.0 0.0 3.8 3 1 0 3 3 2 1 AAA domain NACHT PF05729.7 CDO69714.1 - 0.002 17.8 0.2 0.38 10.3 0.0 3.3 3 1 0 3 3 3 1 NACHT domain AAA_29 PF13555.1 CDO69714.1 - 0.0023 17.4 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 CDO69714.1 - 0.0024 17.0 0.0 1.5 7.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 T2SE PF00437.15 CDO69714.1 - 0.004 16.0 0.0 0.27 10.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 CDO69714.1 - 0.0047 16.8 0.0 0.97 9.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.10 CDO69714.1 - 0.006 16.3 0.4 3.6 7.2 0.0 3.9 4 0 0 4 4 4 1 NTPase ResIII PF04851.10 CDO69714.1 - 0.0078 16.0 0.1 14 5.4 0.0 3.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DNA_pol3_delta2 PF13177.1 CDO69714.1 - 0.008 15.8 0.0 0.066 12.8 0.0 2.4 3 1 0 3 3 2 1 DNA polymerase III, delta subunit SRP54 PF00448.17 CDO69714.1 - 0.013 14.9 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 CDO69714.1 - 0.025 14.1 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.13 CDO69714.1 - 0.045 13.3 0.4 8.2 5.9 0.0 2.8 3 0 0 3 3 2 0 Bacterial dnaA protein AAA_3 PF07726.6 CDO69714.1 - 0.055 13.0 0.0 24 4.5 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 CDO69714.1 - 0.081 13.4 0.0 0.88 10.0 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 CDO69714.1 - 0.11 12.4 0.5 8.5 6.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 CDO69714.1 - 0.13 11.7 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 CDO69714.1 - 1.3 8.5 6.9 9.1 5.7 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.1 CDO69714.1 - 6.5 6.6 11.8 4.6 7.1 0.0 3.9 5 0 0 5 5 2 0 AAA domain Hydrophobin PF01185.13 CDO69715.1 - 1.3e-16 60.8 9.7 1.5e-16 60.5 6.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Pantoate_transf PF02548.10 CDO69715.1 - 0.22 10.6 1.1 0.26 10.3 0.8 1.1 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase LPAM_2 PF13627.1 CDO69716.1 - 0.67 9.7 0.1 0.67 9.7 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site zf-C2H2 PF00096.21 CDO69718.1 - 4.3e-08 33.0 20.4 0.00085 19.5 0.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO69718.1 - 5.8e-07 29.4 12.8 0.0024 18.0 0.1 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CDO69718.1 - 1.3e-05 25.1 18.0 0.0028 17.8 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger DUF2415 PF10313.4 CDO69719.1 - 4.2e-08 32.7 0.3 1.1e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 CDO69719.1 - 0.0019 18.0 3.5 2.2 8.3 0.1 4.5 4 1 1 5 5 5 2 WD domain, G-beta repeat Lon_C PF05362.8 CDO69721.1 - 4.5e-68 228.6 0.2 7.9e-68 227.7 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 CDO69721.1 - 1.3e-38 132.7 0.7 5.8e-38 130.6 0.5 2.1 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 CDO69721.1 - 9.5e-22 77.6 0.0 2.3e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDO69721.1 - 5.3e-08 32.6 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDO69721.1 - 2.6e-06 27.5 0.5 9.3e-05 22.4 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain ChlI PF13541.1 CDO69721.1 - 4.6e-06 26.1 0.3 4.5e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 CDO69721.1 - 8.8e-06 25.7 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CDO69721.1 - 3.5e-05 24.6 0.0 0.00018 22.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 CDO69721.1 - 4.2e-05 22.3 0.0 8.1e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.1 CDO69721.1 - 0.00014 22.0 0.0 0.002 18.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CDO69721.1 - 0.00034 19.7 0.0 0.0023 17.0 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CDO69721.1 - 0.0009 19.1 0.0 0.0029 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDO69721.1 - 0.0015 18.8 2.9 0.0047 17.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CDO69721.1 - 0.0093 14.7 0.1 0.22 10.1 0.1 2.5 3 0 0 3 3 3 1 TIP49 C-terminus RNA_helicase PF00910.17 CDO69721.1 - 0.0097 16.0 0.0 0.06 13.5 0.0 2.2 2 0 0 2 2 2 1 RNA helicase SKI PF01202.17 CDO69721.1 - 0.019 14.8 1.0 0.037 13.9 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase NACHT PF05729.7 CDO69721.1 - 0.025 14.2 0.1 1.3 8.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 CDO69721.1 - 0.031 13.6 0.0 0.095 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CDO69721.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 CDO69721.1 - 0.033 13.6 0.0 0.065 12.7 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 CDO69721.1 - 0.043 12.9 0.0 0.095 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 CDO69721.1 - 0.044 13.7 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CDO69721.1 - 0.048 13.3 0.1 0.34 10.5 0.0 2.4 1 1 1 2 2 2 0 NTPase AAA_24 PF13479.1 CDO69721.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CDO69721.1 - 0.091 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 CDO69721.1 - 0.096 12.9 0.6 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 ABC transporter AAA_21 PF13304.1 CDO69721.1 - 0.22 11.4 1.4 0.96 9.3 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 CDO69721.1 - 1.5 9.1 4.9 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Cyt-b5 PF00173.23 CDO69724.1 - 4.2e-16 58.5 0.0 8.5e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4620 PF15399.1 CDO69724.1 - 0.059 13.5 0.3 0.059 13.5 0.2 3.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4620) ECH PF00378.15 CDO69725.1 - 2.5e-08 33.3 0.0 4.8e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family zf-CCCH PF00642.19 CDO69726.1 - 5.7e-07 29.0 8.5 1.5e-06 27.7 0.6 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) V_ATPase_I PF01496.14 CDO69726.1 - 2.3 5.9 3.8 3.1 5.5 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRM_1 PF00076.17 CDO69727.1 - 7.5e-05 22.2 0.0 0.00015 21.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO69727.1 - 0.00011 21.8 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 CDO69727.1 - 0.0023 17.7 0.0 0.0066 16.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO69727.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RVT_2 PF07727.9 CDO69729.1 - 1.2e-82 276.6 0.0 1.5e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Thioredoxin PF00085.15 CDO69731.1 - 1e-24 86.1 0.0 9.6e-17 60.5 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CDO69731.1 - 0.039 14.1 0.0 0.39 10.9 0.0 2.5 2 2 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDO69731.1 - 0.067 13.3 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like DUF455 PF04305.9 CDO69732.1 - 5.5e-88 294.4 0.0 7.1e-88 294.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 CDO69732.1 - 7.8e-08 31.7 0.1 1.5e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 CDO69732.1 - 0.0019 17.8 0.0 0.007 16.0 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain ATG22 PF11700.3 CDO69733.1 - 1.5e-113 379.8 11.3 1.7e-113 379.6 7.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 CDO69733.1 - 8.5e-08 31.2 39.8 0.00013 20.7 16.2 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.20 CDO69736.1 - 2.8e-72 243.0 0.0 8.8e-72 241.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69736.1 - 2e-37 128.7 0.0 7.3e-37 126.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CDO69736.1 - 2e-06 27.0 0.1 3.4e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CDO69736.1 - 1.3e-05 24.3 0.0 3.6e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CDO69736.1 - 0.00016 21.4 0.2 0.0081 15.9 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 CDO69736.1 - 0.0069 15.6 0.6 0.011 14.9 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 CDO69736.1 - 0.06 12.6 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 CDO69736.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fungal_trans PF04082.13 CDO69738.1 - 1.4e-16 60.1 1.8 2.5e-16 59.3 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rad60-SLD PF11976.3 CDO69739.1 - 1.5e-11 43.8 0.0 2.1e-11 43.3 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CDO69739.1 - 2.4e-05 23.6 0.0 3.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.3 CDO69739.1 - 0.047 13.6 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Alba PF01918.16 CDO69739.1 - 0.12 11.9 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Alba RicinB_lectin_2 PF14200.1 CDO69740.1 - 3.9e-14 52.8 0.0 1.6e-06 28.4 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 CDO69740.1 - 0.00049 20.1 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CDO69741.1 - 2.6e-26 92.0 1.4 1.4e-14 54.3 0.1 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 CDO69741.1 - 5.2e-10 39.4 0.0 2e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 CDO69742.1 - 1.1e-08 35.3 0.1 3.8e-06 27.2 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Mito_carr PF00153.22 CDO69743.1 - 1.5e-21 75.9 8.8 2.1e-09 36.9 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIS_M PF07500.9 CDO69744.1 - 1.2e-31 109.0 0.2 5e-31 107.1 0.0 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CDO69744.1 - 7.5e-17 60.6 11.0 1.3e-16 59.9 7.6 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CDO69744.1 - 9.4e-13 47.4 0.8 1.7e-12 46.6 0.6 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3216 PF11505.3 CDO69744.1 - 0.019 14.7 0.1 0.047 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) zinc_ribbon_5 PF13719.1 CDO69744.1 - 0.2 11.2 2.7 4.5 6.9 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.27 CDO69745.1 - 1.4e-53 176.9 19.7 3.5e-09 36.1 0.1 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 CDO69745.1 - 0.00038 18.7 1.0 1.3 7.1 0.0 3.7 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CDO69745.1 - 0.015 14.7 1.6 0.34 10.3 0.2 2.9 1 1 1 3 3 3 0 PQQ-like domain DUF3328 PF11807.3 CDO69746.1 - 3.1e-18 66.2 0.4 4.1e-18 65.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 CDO69748.1 - 2.3e-13 50.3 2.0 2.5e-13 50.2 1.4 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2231 PF09990.4 CDO69749.1 - 0.25 11.7 5.7 1.7 9.0 0.5 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) But2 PF09792.4 CDO69750.1 - 2.3e-05 24.2 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Acetyltransf_1 PF00583.19 CDO69751.1 - 3.1e-11 43.1 0.0 7.6e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CDO69751.1 - 8.4e-07 29.1 0.0 2.5e-06 27.5 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CDO69751.1 - 1.3e-06 28.4 0.0 4.6e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CDO69751.1 - 3.7e-06 26.8 0.0 6.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO69751.1 - 0.00038 20.1 0.0 0.00075 19.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CDO69751.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CDO69751.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 CDO69751.1 - 0.047 13.6 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M48 PF01435.13 CDO69752.1 - 3.6e-45 154.2 0.0 4.9e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 CDO69752.1 - 0.041 12.8 0.1 0.078 11.9 0.1 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF3784 PF12650.2 CDO69752.1 - 0.051 13.5 1.4 0.16 11.9 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) adh_short PF00106.20 CDO69753.1 - 5.9e-20 71.8 0.4 1.9e-13 50.6 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CDO69753.1 - 4.1e-11 43.0 0.0 4.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO69753.1 - 5e-08 32.8 0.0 3.9e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 CDO69753.1 - 2.3e-07 31.0 0.1 4.9e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CDO69753.1 - 6.9e-05 22.4 0.0 0.00022 20.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CDO69753.1 - 0.0036 17.0 0.2 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Hint_2 PF13403.1 CDO69753.1 - 0.12 12.2 0.0 0.88 9.4 0.0 2.1 2 0 0 2 2 2 0 Hint domain MFS_1 PF07690.11 CDO69754.1 - 3.3e-17 62.2 27.1 1.3e-16 60.3 16.9 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO69754.1 - 0.00031 19.4 16.3 0.026 13.1 5.2 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter 7tm_6 PF02949.15 CDO69755.1 - 0.0024 16.7 1.6 0.0024 16.7 1.1 1.8 2 1 0 2 2 2 1 7tm Odorant receptor Zw10 PF06248.8 CDO69756.1 - 1.8e-13 49.5 0.0 3.7e-06 25.3 0.0 3.1 2 1 1 3 3 3 3 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 CDO69756.1 - 7.1e-11 41.8 0.2 2.9e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Activator-TraM PF11657.3 CDO69756.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 Transcriptional activator TraM Rep_fac_C PF08542.6 CDO69757.1 - 4.5e-18 65.0 0.0 1.6e-17 63.2 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.24 CDO69757.1 - 1.8e-17 63.7 0.0 2.9e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CDO69757.1 - 9.2e-17 61.1 0.0 1.1e-14 54.3 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CDO69757.1 - 9.9e-11 41.0 0.0 2.3e-08 33.1 0.0 2.2 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CDO69757.1 - 2.6e-07 30.6 0.1 9.3e-07 28.8 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 CDO69757.1 - 2.3e-06 27.7 0.2 0.031 14.4 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 CDO69757.1 - 6.2e-06 25.8 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 CDO69757.1 - 6.3e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.8 CDO69757.1 - 7.4e-06 25.0 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 CDO69757.1 - 9.1e-06 25.4 0.2 0.0007 19.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CDO69757.1 - 2.6e-05 23.4 0.0 5.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 CDO69757.1 - 6.4e-05 22.6 0.3 0.00078 19.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CDO69757.1 - 8e-05 22.7 0.0 0.0014 18.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CDO69757.1 - 0.00072 19.2 0.1 0.0086 15.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CDO69757.1 - 0.001 18.6 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 CDO69757.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CDO69757.1 - 0.0024 17.4 0.1 0.041 13.3 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 CDO69757.1 - 0.0074 15.8 0.0 0.016 14.6 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Methyltransf_31 PF13847.1 CDO69757.1 - 0.0092 15.5 0.1 0.022 14.3 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Arch_ATPase PF01637.13 CDO69757.1 - 0.0096 15.6 0.1 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 CDO69757.1 - 0.016 16.0 0.1 0.044 14.6 0.0 1.9 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.1 CDO69757.1 - 0.016 14.6 0.1 0.068 12.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CDO69757.1 - 0.02 14.2 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.10 CDO69757.1 - 0.022 14.5 0.0 0.11 12.2 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TIP49 PF06068.8 CDO69757.1 - 0.04 12.6 0.0 0.31 9.7 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus T2SE PF00437.15 CDO69757.1 - 0.043 12.6 0.0 0.1 11.5 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein SNF2_N PF00176.18 CDO69757.1 - 0.048 12.4 0.1 0.17 10.6 0.0 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_28 PF13521.1 CDO69757.1 - 0.065 13.1 0.0 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CDO69757.1 - 0.074 12.4 0.1 2.1 7.6 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 CDO69757.1 - 0.083 12.0 0.0 0.35 9.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CobA_CobO_BtuR PF02572.10 CDO69757.1 - 0.46 10.0 5.4 4.2 6.9 0.0 3.1 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ubiquitin PF00240.18 CDO69758.1 - 1.4e-34 117.2 0.7 1.4e-34 117.2 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 CDO69758.1 - 1.6e-26 91.8 1.9 3.3e-26 90.8 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CDO69758.1 - 7.4e-20 70.4 0.7 1.5e-19 69.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CDO69758.1 - 1.1e-05 25.5 0.4 5e-05 23.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CDO69758.1 - 0.00021 21.0 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CDO69758.1 - 0.00029 20.6 0.5 0.00064 19.5 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2207 PF09972.4 CDO69758.1 - 0.0042 15.7 0.8 0.0048 15.5 0.6 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF2407 PF10302.4 CDO69758.1 - 0.0055 16.8 0.8 0.0073 16.4 0.6 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF971 PF06155.7 CDO69758.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) IBR PF01485.16 CDO69758.1 - 0.042 13.7 0.9 0.065 13.1 0.6 1.4 1 0 0 1 1 1 0 IBR domain Plexin_cytopl PF08337.7 CDO69758.1 - 0.053 11.8 3.5 0.35 9.1 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Stig1 PF04885.8 CDO69758.1 - 0.056 13.6 0.1 0.088 13.0 0.1 1.4 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF2870 PF11069.3 CDO69758.1 - 0.12 12.3 1.5 0.14 12.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) MMS19_C PF12460.3 CDO69761.1 - 2.6e-83 280.0 6.5 3.5e-83 279.6 1.6 2.4 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 CDO69761.1 - 1.2e-57 195.1 4.8 3.1e-50 170.8 0.1 4.5 4 1 1 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 CDO69761.1 - 1.4e-08 34.8 10.8 0.022 15.0 0.0 6.3 4 2 1 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 CDO69761.1 - 3.6e-05 24.1 14.4 0.0014 19.0 0.1 6.5 6 0 0 6 6 6 1 HEAT-like repeat Ipi1_N PF12333.3 CDO69761.1 - 0.00027 20.8 1.0 3.7 7.5 0.0 4.6 4 1 1 5 5 5 2 Rix1 complex component involved in 60S ribosome maturation RIX1 PF08167.7 CDO69761.1 - 0.032 13.9 3.0 2.1 7.9 0.0 3.8 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis HEAT PF02985.17 CDO69761.1 - 0.36 11.0 9.8 78 3.7 0.1 6.3 6 0 0 6 6 6 0 HEAT repeat Arrestin_N PF00339.24 CDO69762.1 - 0.072 12.9 0.0 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DUF2706 PF10913.3 CDO69762.1 - 0.1 12.1 0.2 0.18 11.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2706) Methyltransf_28 PF02636.12 CDO69763.1 - 5.5e-35 120.9 0.0 9.4e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 CDO69763.1 - 0.0068 16.9 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO69763.1 - 0.013 15.9 0.0 0.055 13.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 CDO69763.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 CDO69763.1 - 0.078 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CDO69763.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Tmemb_14 PF03647.8 CDO69764.1 - 1.5e-17 63.7 7.0 1.7e-17 63.5 4.9 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C AftA_N PF12250.3 CDO69764.1 - 0.0041 15.8 0.4 0.0042 15.8 0.3 1.2 1 0 0 1 1 1 1 Arabinofuranosyltransferase N terminal MtrC PF04211.8 CDO69764.1 - 0.0087 15.1 3.0 0.0088 15.1 2.1 1.1 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit C DUF2416 PF10315.4 CDO69764.1 - 0.12 12.5 1.8 0.22 11.8 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) DUF3188 PF11384.3 CDO69764.1 - 7 6.3 6.7 0.76 9.3 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3188) Methyltransf_11 PF08241.7 CDO69765.1 - 1.5e-09 38.2 0.0 2.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO69765.1 - 2.1e-08 34.7 0.0 2.7e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO69765.1 - 2e-07 30.6 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO69765.1 - 4.7e-07 30.1 0.0 6.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO69765.1 - 0.0001 22.7 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO69765.1 - 0.00029 20.5 0.0 0.00037 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CDO69765.1 - 0.0017 17.7 0.1 0.0041 16.5 0.1 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 CDO69765.1 - 0.0095 14.9 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 CDO69765.1 - 0.057 13.1 0.0 0.07 12.8 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CDO69765.1 - 0.061 12.7 0.0 0.092 12.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 CDO69765.1 - 0.075 12.1 0.1 0.097 11.7 0.1 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TRM13 PF05206.9 CDO69765.1 - 0.082 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Voltage_CLC PF00654.15 CDO69766.1 - 5.4e-87 292.1 26.4 5.4e-87 292.1 18.3 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CDO69766.1 - 3.1e-08 33.2 0.1 0.011 15.5 0.0 2.8 2 0 0 2 2 2 2 CBS domain DSPc PF00782.15 CDO69767.1 - 6.5e-33 113.1 0.0 9.1e-33 112.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDO69767.1 - 0.00023 20.5 0.1 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 CDO69767.1 - 0.0029 16.9 0.1 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 CDO69767.1 - 0.0031 16.9 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.7 CDO69767.1 - 0.011 14.6 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 CDO69767.1 - 0.088 12.8 0.1 0.088 12.8 0.1 1.5 2 0 0 2 2 2 0 Inositol hexakisphosphate Peptidase_S10 PF00450.17 CDO69768.1 - 2.4e-55 188.4 0.0 6.3e-47 160.6 0.0 2.3 2 1 0 2 2 2 2 Serine carboxypeptidase ZZ PF00569.12 CDO69770.1 - 6.2e-18 64.0 60.1 2.3e-07 30.2 4.6 6.2 6 0 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.19 CDO69770.1 - 0.00035 20.1 0.0 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 PB1 domain Yippee-Mis18 PF03226.9 CDO69770.1 - 0.095 12.7 0.1 0.095 12.7 0.1 4.5 5 1 0 5 5 5 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FAM220 PF15487.1 CDO69770.1 - 0.27 10.5 5.0 0.53 9.6 3.5 1.4 1 0 0 1 1 1 0 FAM220 family Med4 PF10018.4 CDO69771.1 - 5.3e-27 94.4 0.0 7.3e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Peptidase_S10 PF00450.17 CDO69772.1 - 2.6e-46 158.6 0.7 7.9e-31 107.6 0.6 2.8 3 0 0 3 3 3 2 Serine carboxypeptidase Carn_acyltransf PF00755.15 CDO69773.1 - 4.6e-145 484.0 0.0 5.3e-145 483.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Polysacc_deac_1 PF01522.16 CDO69774.1 - 2.4e-27 94.9 0.0 5.7e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Sec1 PF00995.18 CDO69775.1 - 9.7e-132 440.4 0.0 1.2e-131 440.1 0.0 1.1 1 0 0 1 1 1 1 Sec1 family CNH PF00780.17 CDO69776.1 - 2.6e-79 266.5 0.0 4.6e-79 265.7 0.0 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 CDO69776.1 - 1.4e-42 144.8 0.1 2.7e-42 143.9 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 CDO69776.1 - 2e-38 132.1 0.0 3.1e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 CDO69776.1 - 1e-13 50.8 0.1 2.2e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 CDO69776.1 - 0.00061 19.9 0.0 0.0023 18.1 0.0 2.1 2 0 0 2 2 2 1 PH domain EI24 PF07264.6 CDO69778.1 - 6.2e-06 25.8 14.7 6.2e-06 25.8 10.2 1.9 2 1 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) DnaJ-X PF14308.1 CDO69779.1 - 1.4e-57 194.2 2.1 2e-57 193.7 0.1 2.2 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CDO69779.1 - 4.4e-15 55.1 1.0 3.7e-08 32.9 0.1 3.1 3 0 0 3 3 3 2 DnaJ domain PspB PF06667.7 CDO69779.1 - 0.9 9.5 5.9 0.29 11.1 1.2 2.3 2 0 0 2 2 2 0 Phage shock protein B DUF3292 PF11696.3 CDO69780.1 - 0.011 13.6 1.8 0.0098 13.8 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) WLM PF08325.5 CDO69781.1 - 5.2e-41 140.5 0.1 8.9e-41 139.8 0.1 1.3 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.18 CDO69781.1 - 3.3e-08 32.8 0.0 5.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CDO69781.1 - 0.0048 16.5 0.0 0.014 15.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Peptidase_MA_2 PF13485.1 CDO69781.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily Ubiquitin_2 PF14560.1 CDO69781.1 - 0.043 14.0 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain BTB PF00651.26 CDO69783.1 - 1.3e-14 54.0 0.0 9.7e-06 25.5 0.0 3.1 2 1 0 2 2 2 2 BTB/POZ domain RCC1 PF00415.13 CDO69783.1 - 1.3e-13 50.9 0.0 0.004 17.3 0.0 4.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.1 CDO69783.1 - 3.5e-11 42.9 3.5 9.1e-06 25.7 0.2 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDO69783.1 - 4.6e-10 39.7 0.6 0.00034 21.0 0.1 3.2 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CDO69783.1 - 3.4e-08 33.7 0.0 3.5e-06 27.2 0.0 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CDO69783.1 - 4.1e-07 29.6 0.4 0.072 13.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 CDO69783.1 - 3.4e-05 23.4 1.4 0.13 12.1 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat DUF3686 PF12458.3 CDO69784.1 - 0.092 10.9 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 ATPase involved in DNA repair Nop14 PF04147.7 CDO69785.1 - 7.8 4.2 19.7 14 3.4 13.6 1.3 1 0 0 1 1 1 0 Nop14-like family E1-E2_ATPase PF00122.15 CDO69787.1 - 3.4e-44 150.6 5.7 6.3e-44 149.7 4.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CDO69787.1 - 3.2e-30 106.1 0.4 5.7e-30 105.3 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDO69787.1 - 6e-12 46.1 0.0 1.1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CDO69787.1 - 0.00032 20.7 0.1 0.00078 19.5 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 CDO69787.1 - 0.14 11.7 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase p450 PF00067.17 CDO69788.1 - 4.9e-61 206.6 0.0 2.1e-60 204.6 0.0 2.0 2 1 0 2 2 2 1 Cytochrome P450 UvrD-helicase PF00580.16 CDO69790.1 - 0.18 11.0 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain VPS9 PF02204.13 CDO69791.1 - 6.4e-18 64.6 0.0 3.6e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain DDHD PF02862.12 CDO69791.1 - 1.1 9.0 5.5 8.5 6.0 0.0 2.4 2 0 0 2 2 2 0 DDHD domain BSP_II PF05432.6 CDO69791.1 - 1.4 8.0 18.6 0.41 9.8 3.9 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF3537 PF12056.3 CDO69791.1 - 1.5 7.4 1.3 2.9 6.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) CENP-B_dimeris PF09026.5 CDO69791.1 - 1.9 8.7 15.4 0.15 12.3 4.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF506 PF04720.7 CDO69791.1 - 7.5 6.1 9.2 9.2 5.8 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF506) Pro_isomerase PF00160.16 CDO69793.1 - 2.5e-29 102.4 0.0 6.4e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thymidylate_kin PF02223.12 CDO69794.1 - 1.6e-46 158.0 0.0 1.9e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 CDO69794.1 - 0.00058 19.8 0.0 0.0014 18.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDO69794.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 CDO69794.1 - 0.12 12.6 0.1 0.42 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain Zds_C PF08632.5 CDO69796.1 - 1.4e-22 78.8 0.5 2.5e-22 78.0 0.3 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2076 PF09849.4 CDO69796.1 - 0.011 15.7 0.6 0.011 15.7 0.4 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) ApoLp-III PF07464.6 CDO69803.1 - 0.07 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) EF-hand_1 PF00036.27 CDO69805.1 - 0.027 13.7 0.0 0.11 11.8 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 CDO69805.1 - 0.13 12.2 0.4 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Plasmid_RAQPRD PF09686.5 CDO69806.1 - 0.012 15.6 0.1 8.5 6.5 0.0 2.9 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) LSM PF01423.17 CDO69807.1 - 1.4e-10 40.5 0.0 1.6e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain DUF2421 PF10334.4 CDO69808.1 - 4e-57 193.4 0.0 9.3e-57 192.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 CDO69808.1 - 6.9e-53 180.0 4.5 1.8e-52 178.7 3.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CDO69808.1 - 9.3e-08 32.0 17.2 9.3e-08 32.0 11.9 3.2 2 1 0 2 2 2 1 Fusaric acid resistance protein-like WD40 PF00400.27 CDO69809.1 - 2.2e-36 122.4 15.9 1.3e-08 34.3 0.0 9.1 9 0 0 9 9 9 6 WD domain, G-beta repeat NACHT PF05729.7 CDO69809.1 - 3.4e-07 30.0 0.4 1.2e-06 28.3 0.3 1.9 1 1 0 1 1 1 1 NACHT domain eIF2A PF08662.6 CDO69809.1 - 7.5e-05 22.5 0.0 0.038 13.7 0.0 3.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CDO69809.1 - 8.7e-05 20.9 0.0 0.12 10.6 0.0 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain AAA_22 PF13401.1 CDO69809.1 - 0.0018 18.4 0.0 0.0047 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CDO69809.1 - 0.012 14.5 0.0 0.021 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 CDO69809.1 - 0.013 14.5 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain HAD_2 PF13419.1 CDO69811.1 - 1.4e-19 71.0 0.0 1.8e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CDO69811.1 - 7.3e-09 35.2 0.1 1.2e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CDO69811.1 - 2.8e-06 27.8 0.0 4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.21 CDO69811.1 - 0.023 14.2 0.6 0.052 13.0 0.4 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HSP70 PF00012.15 CDO69812.1 - 2.1e-59 201.0 1.2 3.1e-44 150.9 0.1 3.5 2 2 1 4 4 4 2 Hsp70 protein MreB_Mbl PF06723.8 CDO69812.1 - 2e-09 36.5 0.0 6.4e-09 34.8 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein Radial_spoke PF04712.7 CDO69812.1 - 0.34 9.6 9.7 0.53 8.9 6.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Myc_N PF01056.13 CDO69812.1 - 0.37 9.9 5.9 0.8 8.8 4.1 1.5 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 CDO69812.1 - 0.39 9.9 11.5 0.83 8.8 8.0 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) IFT57 PF10498.4 CDO69812.1 - 0.42 9.2 5.2 0.69 8.5 3.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2890 PF11081.3 CDO69812.1 - 2.9 7.9 10.7 6.4 6.7 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) UCH PF00443.24 CDO69813.1 - 1.8e-49 168.2 0.0 3.8e-49 167.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 CDO69813.1 - 8.2e-25 85.9 1.8 1.4e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 CDO69813.1 - 1.1e-18 67.6 0.0 2e-17 63.6 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CDO69813.1 - 1.3e-06 28.4 1.8 5.6e-06 26.3 1.2 2.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UBA_4 PF14555.1 CDO69813.1 - 0.074 12.5 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain NAP PF00956.13 CDO69814.1 - 4.5e-77 258.4 3.7 4.5e-77 258.4 2.6 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) S-antigen PF05756.6 CDO69814.1 - 1.4 8.9 8.1 5.9 6.9 5.6 2.1 1 0 0 1 1 1 0 S-antigen protein zf-4CXXC_R1 PF10497.4 CDO69815.1 - 1.7e-12 47.4 13.6 3.7e-12 46.2 9.4 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Pkinase PF00069.20 CDO69817.1 - 3.9e-29 101.6 0.0 1.1e-28 100.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69817.1 - 1.8e-10 40.3 0.1 0.00057 19.0 0.0 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase GMC_oxred_N PF00732.14 CDO69819.1 - 7.1e-55 186.2 0.0 9.7e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO69819.1 - 6.5e-34 117.2 0.0 1.1e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CDO69819.1 - 0.00026 20.0 0.1 0.0012 17.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CDO69819.1 - 0.0011 17.9 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 CDO69819.1 - 0.002 18.1 0.0 0.0046 16.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDO69819.1 - 0.0025 17.7 0.0 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CDO69819.1 - 0.0039 16.1 0.2 0.17 10.6 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 CDO69819.1 - 0.045 13.8 0.1 1.8 8.5 0.1 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO69819.1 - 0.062 13.0 0.2 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CDO69820.1 - 4.3e-22 79.1 0.0 1.1e-21 77.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CDO69820.1 - 1.4e-17 63.1 0.0 2.6e-16 58.9 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CDO69820.1 - 4.6e-13 48.7 0.0 7.1e-09 35.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CDO69820.1 - 5.8e-10 39.3 0.0 1.2e-08 35.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO69820.1 - 3.8e-07 30.4 0.4 0.004 17.5 0.0 3.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO69820.1 - 0.00014 21.7 0.1 0.0026 17.7 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CDO69820.1 - 0.00016 20.8 0.3 0.0027 16.8 0.2 2.2 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 CDO69820.1 - 0.00032 19.7 0.3 0.036 12.9 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 CDO69820.1 - 0.0014 17.8 0.0 0.029 13.5 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 CDO69820.1 - 0.0033 15.9 0.0 0.064 11.7 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 CDO69820.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 CDO69820.1 - 0.034 14.3 0.0 24 5.2 0.0 3.2 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 CDO69820.1 - 0.038 13.6 0.1 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 CDO69820.1 - 0.047 12.5 0.1 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A SnoaL_2 PF12680.2 CDO69820.1 - 0.077 13.4 0.1 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like domain Gti1_Pac2 PF09729.4 CDO69822.1 - 2.6e-43 147.7 0.7 2.9e-42 144.3 0.5 2.1 1 1 0 1 1 1 1 Gti1/Pac2 family Oxysterol_BP PF01237.13 CDO69823.1 - 2.3e-120 401.3 0.0 3.9e-120 400.5 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.1 CDO69823.1 - 2.8e-16 59.1 1.9 5.1e-09 36.1 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CDO69823.1 - 1.8e-15 55.8 1.8 0.00038 20.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 CDO69823.1 - 1.2e-14 54.4 0.1 6.2e-09 36.0 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CDO69823.1 - 1.5e-13 49.5 0.7 0.0041 17.2 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 CDO69823.1 - 3.2e-13 49.8 0.4 8.1e-06 26.2 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 CDO69823.1 - 1.4e-09 38.0 0.0 4e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CDO69823.1 - 4.1e-06 27.0 0.9 1.9e-05 24.8 0.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 CDO69823.1 - 6.7e-06 26.0 0.0 1.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Pyr_redox_2 PF07992.9 CDO69824.1 - 1.2e-23 84.0 1.4 4.7e-21 75.5 0.1 4.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.17 CDO69824.1 - 4.2e-21 74.9 0.0 8.5e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.1 CDO69824.1 - 4.5e-19 68.1 0.0 1.2e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 CDO69824.1 - 1.3e-16 60.3 1.5 1.2e-12 47.7 1.8 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.22 CDO69824.1 - 1.1e-14 54.6 1.5 3.9e-13 49.5 0.1 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.12 CDO69824.1 - 6.5e-13 48.1 0.0 1.5e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 CDO69824.1 - 3.9e-11 42.3 1.4 8.5e-11 41.2 0.0 2.2 3 0 0 3 3 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 CDO69824.1 - 0.0013 18.8 0.1 0.21 11.6 0.0 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GYD PF08734.6 CDO69824.1 - 0.014 15.1 0.1 0.36 10.5 0.0 2.5 2 0 0 2 2 2 0 GYD domain NAD_binding_9 PF13454.1 CDO69824.1 - 0.016 15.0 3.0 2.7 7.7 0.1 3.6 2 2 2 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 CDO69824.1 - 0.025 13.4 2.7 1.9 7.2 0.0 3.0 2 1 1 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 CDO69824.1 - 0.068 13.2 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ECH PF00378.15 CDO69825.1 - 5.4e-39 133.7 0.1 6.9e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CDO69825.1 - 0.00011 22.3 0.1 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_C54 PF03416.14 CDO69826.1 - 2e-83 279.7 0.0 8.9e-83 277.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family C54 Ras PF00071.17 CDO69827.1 - 8.4e-39 132.5 0.0 1.1e-36 125.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CDO69827.1 - 3.2e-15 56.6 0.0 5.6e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO69827.1 - 2e-08 33.6 0.0 6.2e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CDO69827.1 - 1.6e-05 24.8 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CDO69827.1 - 1.9e-05 23.9 0.0 2.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDO69827.1 - 0.00022 20.7 0.0 0.00065 19.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CDO69827.1 - 0.0096 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CDO69827.1 - 0.024 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.11 CDO69827.1 - 0.036 13.1 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 AIG1 family DEAD PF00270.24 CDO69828.1 - 3.5e-20 72.1 0.0 6.4e-14 51.7 0.0 3.0 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO69828.1 - 1e-09 38.1 0.0 2.4e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO69828.1 - 0.0075 16.1 0.0 0.016 15.0 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit adh_short PF00106.20 CDO69829.1 - 4.7e-29 101.4 0.0 7.8e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO69829.1 - 4.3e-20 72.5 0.0 5.4e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO69829.1 - 6.6e-10 38.9 0.1 1.4e-09 37.8 0.1 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 CDO69829.1 - 1.6e-06 27.4 0.0 2.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 CDO69829.1 - 9.5e-05 22.4 0.0 0.00016 21.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CDO69829.1 - 0.00018 21.0 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CDO69829.1 - 0.0076 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.10 CDO69829.1 - 0.055 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PAE PF03283.8 CDO69829.1 - 0.06 11.9 0.1 0.084 11.4 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase MCH PF02289.11 CDO69829.1 - 0.09 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Cyclohydrolase (MCH) F-box-like PF12937.2 CDO69830.1 - 9.5e-10 38.0 2.3 1.4e-09 37.5 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDO69830.1 - 1.3 8.7 5.3 1.5 8.5 0.1 3.3 3 1 0 3 3 3 0 F-box domain Aldedh PF00171.17 CDO69831.1 - 3.4e-188 625.6 0.0 3.8e-188 625.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CDO69831.1 - 0.016 13.9 0.2 0.11 11.1 0.1 1.9 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Acetyltransf_3 PF13302.1 CDO69832.1 - 2.1e-14 53.8 0.0 2.6e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO69832.1 - 4.6e-07 29.7 0.0 7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CDO69832.1 - 3.2e-05 23.8 0.0 5.8e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO69832.1 - 0.0011 18.7 0.0 0.0062 16.2 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 CDO69832.1 - 0.018 15.0 0.0 0.09 12.7 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Grp1_Fun34_YaaH PF01184.14 CDO69833.1 - 1.4e-70 236.8 16.6 1.8e-70 236.5 11.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ABC_tran PF00005.22 CDO69834.1 - 4e-24 85.4 0.0 9.1e-24 84.3 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CDO69834.1 - 4.8e-12 46.4 0.0 1.5e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CDO69834.1 - 3.7e-07 29.6 0.0 0.0084 15.3 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CDO69834.1 - 1.7e-06 27.3 0.0 0.047 12.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.1 CDO69834.1 - 0.00034 20.6 0.0 0.00078 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CDO69834.1 - 0.00061 20.5 0.0 0.0013 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CDO69834.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO69834.1 - 0.0015 18.2 0.0 0.0042 16.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 CDO69834.1 - 0.002 17.6 0.0 0.0044 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 CDO69834.1 - 0.0032 17.3 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDO69834.1 - 0.0092 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 CDO69834.1 - 0.019 15.0 0.0 0.051 13.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 CDO69834.1 - 0.02 14.2 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CDO69834.1 - 0.022 14.3 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 CDO69834.1 - 0.093 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Dimer_Tnp_hAT PF05699.9 CDO69834.1 - 0.15 11.7 0.1 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region AAA_18 PF13238.1 CDO69834.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CDO69834.1 - 0.19 10.8 0.0 0.48 9.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_13 PF13166.1 CDO69834.1 - 0.29 9.5 0.0 0.42 9.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Y_phosphatase PF00102.22 CDO69835.1 - 2e-55 187.7 0.6 3e-30 105.2 0.0 3.9 3 1 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 CDO69835.1 - 4.1e-10 40.0 0.0 1e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 CDO69835.1 - 0.00098 19.4 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 CDO69835.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 CDO69835.1 - 0.33 10.3 0.0 0.6 9.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family F-box-like PF12937.2 CDO69836.1 - 0.0007 19.2 2.7 0.0012 18.4 0.1 2.6 3 0 0 3 3 3 1 F-box-like V-ATPase_C PF03223.10 CDO69836.1 - 0.14 11.0 0.1 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit C LRR_8 PF13855.1 CDO69836.1 - 0.17 11.6 1.3 0.94 9.2 0.1 2.9 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 CDO69836.1 - 0.25 11.0 1.0 2.1 8.0 0.2 2.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) ABC_tran PF00005.22 CDO69837.1 - 1.6e-24 86.7 0.0 5.1e-24 85.1 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CDO69837.1 - 8e-12 45.7 0.0 1.4e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CDO69837.1 - 3.9e-08 32.7 0.0 0.0067 15.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CDO69837.1 - 5.9e-06 25.6 0.0 0.066 12.4 0.1 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CDO69837.1 - 0.00016 22.0 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDO69837.1 - 0.00027 21.7 0.0 0.00091 20.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CDO69837.1 - 0.00056 19.3 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 CDO69837.1 - 0.0018 17.9 0.0 0.0045 16.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CDO69837.1 - 0.0068 16.4 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CDO69837.1 - 0.014 15.5 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CDO69837.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 CDO69837.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CDO69837.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 CDO69837.1 - 0.025 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CDO69837.1 - 0.052 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CDO69837.1 - 0.058 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain MutS_V PF00488.16 CDO69837.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 MutS domain V APS_kinase PF01583.15 CDO69837.1 - 0.086 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_13 PF13166.1 CDO69837.1 - 0.13 10.7 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CDO69837.1 - 0.13 12.5 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CDO69837.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UMP1 PF05348.6 CDO69838.1 - 1e-22 80.4 2.9 1.2e-22 80.3 2.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 PARP_reg PF02877.9 CDO69839.1 - 4.3e-50 168.8 0.0 5.3e-36 123.2 0.0 2.4 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 CDO69839.1 - 1.1e-38 131.0 8.8 1.1e-20 73.3 0.1 3.1 3 0 0 3 3 3 2 WGR domain PARP PF00644.15 CDO69839.1 - 5.7e-33 114.0 10.3 2.2e-13 50.1 0.0 4.7 4 3 1 5 5 5 3 Poly(ADP-ribose) polymerase catalytic domain DUF659 PF04937.10 CDO69842.1 - 2.2e-07 30.4 0.1 3.8e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) GPI-anchored PF10342.4 CDO69843.1 - 6.6e-08 32.9 0.2 1.3e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MFS_1 PF07690.11 CDO69845.1 - 2.1e-25 89.1 52.0 1.9e-16 59.7 8.9 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO69845.1 - 4.7e-23 81.4 19.8 2.1e-19 69.4 2.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter CMAS PF02353.15 CDO69847.1 - 1.1e-44 152.6 0.0 7.7e-29 100.6 0.0 4.7 5 0 0 5 5 5 4 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CDO69847.1 - 5.8e-07 30.0 0.0 1.3e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDO69847.1 - 1.1e-05 24.8 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CDO69847.1 - 4.8e-05 23.1 0.0 9.6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO69847.1 - 0.0021 18.0 0.1 0.0077 16.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.5 CDO69847.1 - 0.0065 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_12 PF08242.7 CDO69847.1 - 0.0087 16.5 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO69847.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CDO69847.1 - 0.042 14.2 0.0 0.09 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 CDO69847.1 - 0.062 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 CDO69847.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 CDO69847.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF3693 PF12472.3 CDO69848.1 - 0.079 12.5 0.3 0.26 10.8 0.2 1.9 1 0 0 1 1 1 0 Phage related protein ICMT PF04140.9 CDO69849.1 - 1.7e-17 63.3 0.2 1.6e-15 57.0 0.0 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO69849.1 - 5.1e-11 42.6 0.3 2.2e-10 40.5 0.1 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO69849.1 - 3.1e-09 35.8 0.0 4.3e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 CDO69850.1 - 4.4e-15 55.6 0.0 9e-15 54.6 0.0 1.5 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO69850.1 - 2.7e-12 46.7 0.0 3.9e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO69850.1 - 9e-08 31.0 0.0 1.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CDO69850.1 - 0.02 14.1 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) NnrU PF07298.6 CDO69850.1 - 0.022 14.1 0.2 0.036 13.4 0.1 1.3 1 1 0 1 1 1 0 NnrU protein ICMT PF04140.9 CDO69852.1 - 9.8e-14 51.3 2.6 1.5e-13 50.7 0.0 2.5 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO69852.1 - 1.3e-12 47.7 0.6 5.9e-12 45.6 0.4 2.1 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO69852.1 - 2.9e-05 22.8 0.0 4.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CDO69852.1 - 0.028 13.6 0.4 0.041 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ICMT PF04140.9 CDO69853.1 - 1.4e-13 50.8 0.1 4.9e-12 45.9 0.0 2.5 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO69853.1 - 3.2e-12 46.4 0.5 2.1e-10 40.6 0.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO69853.1 - 6e-05 21.7 0.0 0.0001 20.9 0.0 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PRP1_N PF06424.7 CDO69855.1 - 5.1e-49 166.0 8.3 7.2e-49 165.5 2.0 2.5 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CDO69855.1 - 1.2e-27 93.8 34.8 0.00043 20.6 0.1 14.5 4 4 11 15 15 15 8 Tetratricopeptide repeat TPR_16 PF13432.1 CDO69855.1 - 2.6e-19 69.3 24.0 4.2e-08 33.6 0.1 8.4 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 CDO69855.1 - 3.1e-16 59.4 19.8 0.0049 17.1 0.1 9.1 6 3 6 12 12 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 CDO69855.1 - 1.8e-07 30.6 12.2 0.0029 17.2 0.5 7.3 6 2 2 8 8 8 2 TPR repeat TPR_6 PF13174.1 CDO69855.1 - 1.2e-06 28.5 12.2 0.38 11.3 0.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDO69855.1 - 1.1e-05 24.9 18.9 0.019 14.8 0.2 9.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDO69855.1 - 2.6e-05 24.0 3.1 5.5 7.4 0.1 7.5 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO69855.1 - 0.00051 19.6 2.9 0.24 11.2 0.1 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDO69855.1 - 0.0009 19.1 10.5 0.12 12.3 0.5 6.8 7 1 1 8 8 8 1 Tetratricopeptide repeat DUF3808 PF10300.4 CDO69855.1 - 0.0019 16.8 0.9 1.2 7.6 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3808) TPR_9 PF13371.1 CDO69855.1 - 0.0023 17.7 7.1 0.73 9.7 0.1 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.3 CDO69855.1 - 0.003 16.3 0.1 0.003 16.3 0.1 4.4 4 1 0 5 5 5 1 NMDA receptor-regulated protein 1 TPR_21 PF09976.4 CDO69855.1 - 0.0037 17.1 20.0 0.016 15.1 3.8 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDO69855.1 - 0.0069 15.9 2.9 1.5 8.5 0.3 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Asp PF00026.18 CDO69856.1 - 2.1e-44 152.0 0.1 3e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO69856.1 - 5.1e-07 29.7 7.8 5.2e-07 29.7 1.3 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO69856.1 - 0.061 13.8 3.9 1.2 9.6 1.4 3.0 2 1 0 2 2 2 0 Aspartyl protease Mito_carr PF00153.22 CDO69857.1 - 3.5e-35 119.5 0.6 7.6e-14 51.1 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Ecl1 PF12855.2 CDO69858.1 - 0.0047 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Life-span regulatory factor DUF3049 PF11250.3 CDO69858.1 - 0.012 15.3 3.2 0.16 11.7 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3049) zf-rbx1 PF12678.2 CDO69859.1 - 4.8e-09 36.1 0.2 1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CDO69859.1 - 1.5e-08 34.2 4.4 7.6e-08 32.0 3.0 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDO69859.1 - 0.0036 17.2 2.3 0.0036 17.2 1.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO69859.1 - 0.004 16.7 2.0 0.017 14.7 1.4 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO69859.1 - 0.007 16.0 1.6 0.013 15.1 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CsbD PF05532.7 CDO69859.1 - 0.0085 15.7 0.2 0.021 14.4 0.1 1.6 1 0 0 1 1 1 1 CsbD-like zf-RING_5 PF14634.1 CDO69859.1 - 0.039 13.6 3.1 0.092 12.4 2.2 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 CDO69859.1 - 0.061 13.1 0.3 0.061 13.1 0.2 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger TBCA PF02970.11 CDO69859.1 - 0.17 11.9 0.1 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 Tubulin binding cofactor A RINGv PF12906.2 CDO69859.1 - 0.4 10.7 3.2 0.18 11.8 0.3 1.8 2 0 0 2 2 2 0 RING-variant domain Hist_deacetyl PF00850.14 CDO69860.1 - 1.5e-62 211.6 1.0 1.9e-62 211.3 0.7 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DAO PF01266.19 CDO69862.1 - 3.2e-52 177.6 0.1 4.3e-52 177.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CDO69862.1 - 7e-08 31.9 0.4 1.4e-06 27.7 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDO69862.1 - 3e-07 29.6 6.0 2.6e-06 26.5 4.1 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CDO69862.1 - 0.00046 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CDO69862.1 - 0.0015 17.5 0.2 0.23 10.3 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 CDO69862.1 - 0.0017 18.3 0.7 0.0065 16.4 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CDO69862.1 - 0.002 17.2 1.4 0.039 13.0 1.1 2.2 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CDO69862.1 - 0.0026 16.6 0.5 0.063 12.1 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 CDO69862.1 - 0.0069 16.0 0.1 0.016 14.8 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CDO69862.1 - 0.01 16.2 0.3 0.026 14.9 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO69862.1 - 0.023 13.1 0.3 0.035 12.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 CDO69862.1 - 0.034 13.2 0.9 0.05 12.6 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Histone PF00125.19 CDO69863.1 - 3.9e-30 103.7 0.8 6.6e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CDO69863.1 - 1.4e-05 25.2 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CDO69863.1 - 0.00073 19.5 0.9 0.0013 18.7 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CDO69863.1 - 0.015 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 CDO69863.1 - 0.19 10.9 2.0 0.25 10.5 1.4 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T SPRY PF00622.23 CDO69865.1 - 8.2e-07 29.1 0.0 1.8e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 SPRY domain GDA1_CD39 PF01150.12 CDO69866.1 - 4e-88 295.7 0.0 5.4e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family bZIP_1 PF00170.16 CDO69866.1 - 3.6e-05 23.6 6.0 7.7e-05 22.5 4.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CDO69866.1 - 0.063 13.1 8.1 0.14 11.9 5.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Ppx-GppA PF02541.11 CDO69866.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RhoGAP PF00620.22 CDO69867.1 - 1.5e-30 105.7 0.0 2.6e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 CDO69867.1 - 1.3e-27 96.4 0.7 2e-26 92.6 0.3 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CDO69867.1 - 8.9e-05 22.0 0.1 0.00017 21.0 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Methyltransf_11 PF08241.7 CDO69868.1 - 2.6e-25 88.7 0.0 4.8e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO69868.1 - 4.5e-25 88.0 0.0 5.7e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDO69868.1 - 9e-17 60.9 0.0 1.1e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CDO69868.1 - 1.8e-16 60.4 0.0 2.5e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO69868.1 - 5.5e-15 55.5 0.0 8.1e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO69868.1 - 4.7e-14 52.9 0.0 1.5e-13 51.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO69868.1 - 2.2e-13 50.2 0.1 4.4e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO69868.1 - 2.5e-10 40.4 0.1 5.6e-10 39.2 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 CDO69868.1 - 2.8e-08 33.3 0.0 3.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 CDO69868.1 - 1.5e-06 27.7 0.0 2.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.11 CDO69868.1 - 2.2e-06 26.3 0.0 3.5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 CDO69868.1 - 1e-05 24.6 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 CDO69868.1 - 0.00024 20.7 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 CDO69868.1 - 0.00055 19.0 0.0 0.00073 18.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 CDO69868.1 - 0.0012 17.8 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 CDO69868.1 - 0.018 14.0 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NodS PF05401.6 CDO69868.1 - 0.035 13.5 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) UPF0020 PF01170.13 CDO69868.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Na_H_Exchanger PF00999.16 CDO69869.1 - 2.6e-51 174.3 41.9 2.3e-50 171.2 22.2 2.1 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family PH_3 PF14593.1 CDO69869.1 - 0.27 11.1 0.0 0.51 10.2 0.0 1.4 1 0 0 1 1 1 0 PH domain Nop PF01798.13 CDO69870.1 - 1.3e-59 199.8 0.0 2.7e-59 198.7 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CDO69870.1 - 8.8e-27 92.6 0.1 2.3e-26 91.3 0.1 1.8 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CDO69870.1 - 9.7e-21 73.7 0.2 9.7e-21 73.7 0.1 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain zf-RING_2 PF13639.1 CDO69872.1 - 2.6e-14 52.7 9.4 5e-09 35.8 1.4 3.3 3 0 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.2 CDO69872.1 - 9.6e-08 32.0 1.7 5.5e-05 23.1 0.1 2.9 3 1 0 3 3 3 2 RING-H2 zinc finger zf-RING_5 PF14634.1 CDO69872.1 - 1.5e-05 24.6 6.0 0.00076 19.1 0.3 3.1 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CDO69872.1 - 2.2e-05 24.3 1.7 2.2e-05 24.3 1.2 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO69872.1 - 7.4e-05 22.3 5.5 0.0014 18.2 0.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO69872.1 - 0.00031 20.3 0.4 0.00031 20.3 0.3 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDO69872.1 - 0.0011 18.7 4.6 0.0018 18.0 0.1 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CDO69872.1 - 0.033 14.2 0.4 0.1 12.6 0.3 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 CDO69872.1 - 0.38 10.5 4.1 0.13 11.9 0.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 CDO69872.1 - 1.2 9.1 5.9 2.2 8.2 0.1 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.24 CDO69872.1 - 8.3 6.1 9.4 5 6.8 0.7 2.7 2 1 0 2 2 2 0 PHD-finger PSS PF03034.10 CDO69873.1 - 1.4e-72 244.4 8.1 2.3e-72 243.7 5.6 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase NRDE PF05742.7 CDO69875.1 - 1.4e-41 142.6 0.0 2.2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 NRDE protein Actin PF00022.14 CDO69876.1 - 3.3e-37 127.8 0.0 4.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Actin Kin17_mid PF10357.4 CDO69878.1 - 5.8e-49 164.9 1.3 5.8e-49 164.9 0.9 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 CDO69878.1 - 0.00027 21.0 5.6 0.0006 19.9 3.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CDO69878.1 - 0.00099 19.1 4.9 0.0021 18.1 3.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 CDO69878.1 - 0.072 12.8 1.4 0.15 11.7 1.0 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.2 CDO69878.1 - 0.17 11.9 3.5 0.087 12.9 0.6 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DASH_Ask1 PF08655.5 CDO69879.1 - 3.3e-21 74.8 0.1 5.9e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 DUF2407 PF10302.4 CDO69880.1 - 6.8e-19 67.8 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.1 CDO69880.1 - 3.2e-18 65.9 7.6 2.5e-15 56.6 5.3 3.2 1 1 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.18 CDO69880.1 - 5.1e-08 32.1 0.0 8.7e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 CDO69880.1 - 0.015 15.1 0.0 0.15 11.9 0.0 2.5 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 CDO69880.1 - 0.089 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like IBN_N PF03810.14 CDO69881.1 - 4.8e-11 42.4 0.0 5e-09 35.9 0.0 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 CDO69881.1 - 1.9e-08 34.4 0.2 0.0029 17.8 0.0 4.7 5 0 0 5 5 5 2 HEAT repeats DUF2435 PF10363.4 CDO69881.1 - 0.001 18.9 0.1 0.0067 16.2 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 CDO69881.1 - 0.0015 18.9 1.9 0.067 13.7 0.0 4.7 5 0 0 5 5 5 1 HEAT-like repeat RIX1 PF08167.7 CDO69881.1 - 0.002 17.8 0.1 0.1 12.2 0.0 3.0 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.2 CDO69881.1 - 0.0095 16.2 0.0 1.3 9.4 0.0 3.1 1 1 1 2 2 2 2 Vacuolar 14 Fab1-binding region NRDE PF05742.7 CDO69881.1 - 0.016 14.5 0.5 0.032 13.5 0.1 1.7 2 0 0 2 2 2 0 NRDE protein Xpo1 PF08389.7 CDO69881.1 - 0.026 14.4 3.0 0.56 10.1 0.0 4.1 4 1 0 4 4 4 0 Exportin 1-like protein Oxidored_molyb PF00174.14 CDO69882.1 - 1.8e-36 125.1 0.0 4.9e-36 123.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CDO69882.1 - 2.3e-10 40.2 0.0 4.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain TAF PF02969.12 CDO69883.1 - 2.9e-24 84.8 0.2 5.5e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 CDO69883.1 - 8.5e-17 61.0 0.1 1.9e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 CDO69883.1 - 5.6e-07 29.5 0.2 1.9e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 CDO69883.1 - 0.054 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated CENP-S PF15630.1 CDO69883.1 - 0.058 13.5 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CDO69883.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone F-box-like PF12937.2 CDO69884.1 - 2.3e-06 27.1 0.2 4.6e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO69884.1 - 1.5e-05 24.5 0.0 3.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain zf-C2H2_4 PF13894.1 CDO69886.1 - 7.4e-05 22.8 5.0 0.15 12.4 1.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO69886.1 - 0.00095 19.3 4.4 0.051 13.9 0.0 3.3 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO69886.1 - 0.041 14.1 5.5 0.89 9.9 0.1 3.6 3 1 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 CDO69886.1 - 0.14 12.4 0.9 0.45 10.8 0.6 2.0 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Ebp2 PF05890.7 CDO69887.1 - 2.7e-77 259.7 11.1 2.7e-77 259.7 7.7 2.0 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Lactamase_B_2 PF12706.2 CDO69889.1 - 5.8e-08 32.5 0.1 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 CDO69889.1 - 7.6e-06 25.9 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Mus7 PF09462.5 CDO69890.1 - 4.3e-74 250.4 0.0 8.1e-74 249.5 0.0 1.4 1 1 0 1 1 1 1 Mus7/MMS22 family Herpes_DNAp_acc PF04929.7 CDO69890.1 - 3.1 6.6 3.5 6.2 5.6 2.4 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Sugar_tr PF00083.19 CDO69891.1 - 6.3e-20 71.1 11.7 4.4e-16 58.5 3.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CDO69891.1 - 1.6e-16 60.0 47.6 1.3e-11 43.8 20.8 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Gag_spuma PF03276.9 CDO69891.1 - 0.032 12.5 0.0 0.052 11.8 0.0 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Sugar_tr PF00083.19 CDO69892.1 - 1.1e-19 70.3 14.9 1.8e-19 69.7 10.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO69892.1 - 7.2e-16 57.8 38.1 1.8e-15 56.5 26.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO69893.1 - 4e-20 71.8 17.9 2.6e-19 69.1 12.3 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO69893.1 - 8.3e-18 64.2 64.2 7.2e-16 57.8 28.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Avl9 PF09794.4 CDO69895.1 - 5.8e-132 439.7 0.0 7.7e-132 439.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 CDO69895.1 - 3.8e-10 39.4 0.0 0.00035 20.2 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 CDO69895.1 - 1.4e-08 34.3 1.1 7e-06 25.5 0.7 3.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Glyco_hydro_43 PF04616.9 CDO69896.1 - 5.4e-35 120.8 0.5 2.6e-34 118.6 0.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.9 CDO69897.1 - 2.6e-24 85.7 0.3 3.6e-24 85.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ApbA_C PF08546.6 CDO69898.1 - 1e-26 93.3 0.0 1.5e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CDO69898.1 - 0.00018 20.9 0.0 0.00036 20.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA RadC PF04002.10 CDO69898.1 - 0.035 13.7 0.1 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 RadC-like JAB domain DUF3421 PF11901.3 CDO69899.1 - 2.1e-20 72.6 0.2 3.1e-14 52.7 0.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) CBM_5_12 PF02839.9 CDO69899.1 - 0.00034 20.1 2.9 0.0008 18.9 2.0 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain ABA_WDS PF02496.11 CDO69899.1 - 0.023 14.8 0.6 0.072 13.2 0.4 1.8 1 0 0 1 1 1 0 ABA/WDS induced protein DUF1974 PF09317.6 CDO69899.1 - 0.21 10.9 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) DUF3824 PF12868.2 CDO69899.1 - 0.56 11.1 6.9 2.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) PIF1 PF05970.9 CDO69901.1 - 8.2e-53 179.6 0.0 2.3e-50 171.5 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 CDO69901.1 - 7.4e-45 152.9 0.1 1.3e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_5 PF07728.9 CDO69902.1 - 4.8e-120 395.6 0.0 5.9e-20 71.4 0.0 9.9 9 1 1 10 10 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 CDO69902.1 - 1.2e-25 90.2 0.1 0.00013 22.1 0.0 7.3 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 CDO69902.1 - 4.2e-25 87.8 0.0 1.8e-07 30.8 0.0 8.0 8 0 0 8 8 8 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDO69902.1 - 8.1e-21 74.5 0.1 0.0072 16.4 0.0 7.3 6 0 0 6 6 6 4 AAA domain AAA_14 PF13173.1 CDO69902.1 - 7e-17 61.5 0.0 0.002 18.0 0.0 7.4 8 0 0 8 8 7 3 AAA domain AAA_18 PF13238.1 CDO69902.1 - 3.1e-16 59.8 4.4 0.0065 16.7 0.0 7.1 7 0 0 7 7 6 2 AAA domain AAA_17 PF13207.1 CDO69902.1 - 8e-16 58.9 0.0 0.085 13.6 0.0 6.9 6 0 0 6 6 5 3 AAA domain Sigma54_activat PF00158.21 CDO69902.1 - 3.1e-15 56.0 0.0 0.042 13.3 0.0 6.3 7 0 0 7 7 6 4 Sigma-54 interaction domain AAA_16 PF13191.1 CDO69902.1 - 4.7e-14 52.7 33.2 0.004 17.1 0.0 10.9 10 1 0 10 10 9 4 AAA ATPase domain Sigma54_activ_2 PF14532.1 CDO69902.1 - 3.3e-12 46.6 0.6 0.012 15.6 0.0 6.0 6 0 0 6 6 5 2 Sigma-54 interaction domain AAA_19 PF13245.1 CDO69902.1 - 5.6e-12 45.2 5.9 0.017 14.8 0.1 7.0 6 0 0 6 6 6 2 Part of AAA domain AAA_28 PF13521.1 CDO69902.1 - 3.4e-11 43.3 2.8 1.3 9.0 0.0 6.7 6 0 0 6 6 5 2 AAA domain AAA_33 PF13671.1 CDO69902.1 - 8e-11 41.9 0.5 0.095 12.5 0.0 6.4 6 0 0 6 6 5 2 AAA domain Mg_chelatase PF01078.16 CDO69902.1 - 2.5e-10 39.8 0.9 0.62 9.1 0.0 8.1 9 0 0 9 9 8 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CDO69902.1 - 4.5e-10 39.9 0.1 0.3 11.3 0.0 6.2 6 0 0 6 6 5 2 ABC transporter T2SE PF00437.15 CDO69902.1 - 6.4e-10 38.3 0.1 0.078 11.8 0.0 5.8 6 0 0 6 6 6 2 Type II/IV secretion system protein UPF0079 PF02367.12 CDO69902.1 - 7.8e-10 38.4 0.7 1.9 8.1 0.0 6.2 7 0 0 7 7 6 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CDO69902.1 - 5.1e-09 36.2 0.2 3.1 8.0 0.0 6.2 7 0 0 7 7 5 0 RNA helicase MobB PF03205.9 CDO69902.1 - 9.6e-09 35.0 1.4 0.16 11.7 0.0 5.6 5 0 0 5 5 5 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CDO69902.1 - 1.8e-07 31.0 1.4 1.7 8.2 0.0 5.1 4 0 0 4 4 4 2 NACHT domain Miro PF08477.8 CDO69902.1 - 1.8e-07 31.6 0.1 3.9 8.0 0.0 5.9 6 0 0 6 6 5 0 Miro-like protein AAA_29 PF13555.1 CDO69902.1 - 2.3e-07 30.2 1.0 1.9 8.0 0.0 6.1 6 0 0 6 6 6 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CDO69902.1 - 3.6e-07 30.1 0.0 0.034 13.8 0.0 4.9 5 0 0 5 5 5 1 Archaeal ATPase Zeta_toxin PF06414.7 CDO69902.1 - 1.4e-06 27.5 0.0 1.8 7.5 0.0 5.7 6 0 0 6 6 5 1 Zeta toxin DUF815 PF05673.8 CDO69902.1 - 7.7e-06 25.0 0.0 2.2 7.1 0.0 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF815) RuvB_N PF05496.7 CDO69902.1 - 1.9e-05 23.8 1.1 2.5 7.1 0.0 4.9 5 0 0 5 5 4 1 Holliday junction DNA helicase ruvB N-terminus PduV-EutP PF10662.4 CDO69902.1 - 2e-05 24.0 1.3 0.78 9.2 0.0 4.6 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 CDO69902.1 - 9.1e-05 21.9 6.6 4.9 6.5 0.0 6.4 6 0 0 6 6 6 0 AAA domain Rad17 PF03215.10 CDO69902.1 - 0.00013 20.7 0.5 0.42 9.2 0.0 4.4 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 CDO69902.1 - 0.00013 21.1 0.3 4.1 6.5 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CDO69902.1 - 0.00062 19.5 3.2 8.6 6.0 0.1 5.1 5 0 0 5 5 4 0 NTPase SRP54 PF00448.17 CDO69902.1 - 0.00071 19.0 2.0 6.9 6.0 0.0 4.6 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.12 CDO69902.1 - 0.00072 19.0 0.0 3.2 7.1 0.0 4.0 3 0 0 3 3 3 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 CDO69902.1 - 0.0019 18.1 1.8 5.7 6.9 0.0 5.1 6 0 0 6 6 5 0 50S ribosome-binding GTPase ResIII PF04851.10 CDO69902.1 - 0.0087 15.9 0.0 3.7 7.3 0.0 3.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CDO69902.1 - 0.0095 16.2 12.5 7.6 6.8 0.0 6.1 6 0 0 6 6 5 0 AAA domain ArgK PF03308.11 CDO69902.1 - 0.011 14.5 0.1 12 4.5 0.0 3.3 3 0 0 3 3 3 0 ArgK protein Viral_helicase1 PF01443.13 CDO69902.1 - 0.011 15.2 0.1 9.4 5.6 0.0 3.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase PRK PF00485.13 CDO69902.1 - 0.018 14.5 0.4 35 3.8 0.0 4.1 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.1 CDO69902.1 - 0.028 13.9 1.0 60 3.1 0.0 4.3 4 0 0 4 4 4 0 AAA domain SRPRB PF09439.5 CDO69902.1 - 0.037 13.2 0.5 42 3.2 0.0 4.7 5 0 0 5 5 4 0 Signal recognition particle receptor beta subunit CbiA PF01656.18 CDO69902.1 - 0.053 12.9 1.3 1.9 7.8 0.0 3.3 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 CDO69902.1 - 0.068 12.6 1.0 34 3.8 0.0 4.7 6 0 0 6 6 4 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.11 CDO69902.1 - 0.093 11.9 0.2 37 3.4 0.0 3.7 3 0 0 3 3 3 0 PhoH-like protein DEAD PF00270.24 CDO69902.1 - 0.11 11.9 0.5 33 3.9 0.0 3.8 4 0 0 4 4 3 0 DEAD/DEAH box helicase Dynein_heavy PF03028.10 CDO69902.1 - 0.17 9.8 0.0 2.3 6.1 0.0 2.9 4 0 0 4 4 4 0 Dynein heavy chain and region D6 of dynein motor AAA_7 PF12775.2 CDO69902.1 - 0.33 10.0 0.1 21 4.1 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region D3 TIP49 PF06068.8 CDO69902.1 - 0.44 9.2 0.1 24 3.4 0.0 3.0 4 0 0 4 4 3 0 TIP49 C-terminus KaiC PF06745.8 CDO69902.1 - 0.53 9.3 0.3 48 2.9 0.0 2.9 3 0 0 3 3 2 0 KaiC FeoB_N PF02421.13 CDO69902.1 - 1.4 8.1 0.8 76 2.5 0.1 3.2 3 0 0 3 3 2 0 Ferrous iron transport protein B PIF1 PF05970.9 CDO69902.1 - 1.7 7.4 0.2 1.9e+02 0.7 0.0 3.2 3 0 0 3 3 3 0 PIF1-like helicase Y_phosphatase PF00102.22 CDO69902.1 - 2.5 7.3 0.4 21 4.3 0.0 2.6 3 0 0 3 3 2 0 Protein-tyrosine phosphatase ATP_bind_1 PF03029.12 CDO69902.1 - 4 6.9 2.0 94 2.4 0.0 3.6 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein Flavoprotein PF02441.14 CDO69903.1 - 9.9e-38 128.7 0.0 1.2e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein LRR_6 PF13516.1 CDO69904.1 - 2.5e-16 57.8 0.7 0.38 10.9 0.0 7.1 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.2 CDO69904.1 - 2.4e-10 39.7 0.0 0.13 11.8 0.0 5.7 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDO69904.1 - 9.2e-06 25.0 1.2 52 4.4 0.0 6.3 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.1 CDO69904.1 - 0.0074 16.0 5.6 2.4 7.9 0.0 4.8 5 2 0 5 5 5 1 Leucine rich repeat Sigma70_ner PF04546.8 CDO69904.1 - 0.041 13.5 3.5 0.08 12.5 2.4 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region LRR_7 PF13504.1 CDO69904.1 - 0.087 13.0 4.3 36 5.2 0.0 5.1 5 0 0 5 5 5 0 Leucine rich repeat DUF3605 PF12239.3 CDO69905.1 - 8.1e-30 103.7 0.8 4.7e-12 46.0 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3605) SDP_N PF12278.3 CDO69905.1 - 0.022 14.3 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Sex determination protein N terminal DUF2540 PF10802.3 CDO69905.1 - 0.077 12.6 0.1 0.74 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) Tyrosinase PF00264.15 CDO69906.1 - 2.8e-56 191.1 0.4 2.8e-56 191.1 0.3 1.9 2 1 1 3 3 3 1 Common central domain of tyrosinase Rad60-SLD PF11976.3 CDO69907.1 - 2e-10 40.2 0.0 4.4e-06 26.2 0.1 3.0 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like NTR2 PF15458.1 CDO69908.1 - 7.2e-58 195.8 11.9 7.2e-58 195.8 8.2 2.0 3 0 0 3 3 3 1 Nineteen complex-related protein 2 EMP24_GP25L PF01105.19 CDO69908.1 - 0.0098 15.6 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GCFC PF07842.7 CDO69908.1 - 0.013 14.8 0.0 0.035 13.4 0.0 1.7 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein p450 PF00067.17 CDO69911.1 - 3.2e-52 177.6 0.0 3.6e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pex24p PF06398.6 CDO69912.1 - 2.6e-15 56.1 0.2 3.4e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DDE_Tnp_4 PF13359.1 CDO69913.1 - 3.6e-28 98.1 0.0 5.9e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 CDO69913.1 - 7.9e-06 25.5 0.0 5.8e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 CDO69913.1 - 3.1e-05 23.4 0.0 0.00019 20.9 0.0 2.0 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO69913.1 - 0.00024 21.2 0.1 0.00051 20.1 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain Choline_kin_N PF04428.9 CDO69913.1 - 0.14 11.6 0.0 0.39 10.2 0.0 1.7 1 0 0 1 1 1 0 Choline kinase N terminus UVR PF02151.14 CDO69913.1 - 0.46 10.0 2.3 0.97 9.0 1.6 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif Prot_inhib_II PF02428.10 CDO69913.1 - 0.49 10.4 3.2 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family Myb_DNA-bind_4 PF13837.1 CDO69914.1 - 2.6e-09 37.0 0.2 5e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO69914.1 - 2.4e-06 28.0 0.1 3.8e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO69914.1 - 4.6e-05 23.2 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO69914.1 - 0.0072 16.4 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myc_N PF01056.13 CDO69914.1 - 0.016 14.3 1.4 0.016 14.3 1.0 1.6 2 0 0 2 2 2 0 Myc amino-terminal region LAT PF15234.1 CDO69914.1 - 0.016 14.6 1.2 0.029 13.8 0.8 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Sigma70_ner PF04546.8 CDO69914.1 - 0.041 13.5 5.8 0.041 13.4 3.0 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Myb_DNA-binding PF00249.26 CDO69914.1 - 0.17 11.9 1.4 0.38 10.8 0.5 2.1 2 1 0 2 2 2 0 Myb-like DNA-binding domain PBP1_TM PF14812.1 CDO69914.1 - 2.2 8.6 5.9 1.5 9.1 2.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 CDO69914.1 - 4.5 7.5 11.3 9.6 6.5 7.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RhoGEF PF00621.15 CDO69915.1 - 1.5e-35 122.6 0.1 4e-35 121.3 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain DUF331 PF03889.8 CDO69915.1 - 0.2 10.9 1.6 0.45 9.8 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function Myb_DNA-binding PF00249.26 CDO69916.1 - 1.1e-17 63.7 6.6 9e-10 38.4 0.0 3.9 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO69916.1 - 2.3e-17 62.8 6.3 3.8e-13 49.3 0.5 3.8 3 1 2 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CDO69916.1 - 0.063 13.4 0.3 0.063 13.4 0.2 3.9 5 1 0 5 5 5 0 Myb/SANT-like DNA-binding domain Amidohydro_4 PF13147.1 CDO69917.1 - 3.6e-14 53.4 2.5 1.8e-13 51.1 0.4 2.9 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 CDO69917.1 - 6.1e-12 45.1 0.3 9.5e-09 34.9 0.1 2.9 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 CDO69917.1 - 2.2e-06 27.5 0.0 0.00034 20.3 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 CDO69917.1 - 0.00034 19.9 0.1 0.003 16.8 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family Tropomyosin_1 PF12718.2 CDO69918.1 - 0.0049 16.7 2.1 0.48 10.2 0.3 2.4 2 0 0 2 2 2 1 Tropomyosin like CENP-F_leu_zip PF10473.4 CDO69918.1 - 0.012 15.4 5.2 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALIX_LYPXL_bnd PF13949.1 CDO69918.1 - 0.026 13.4 6.1 0.025 13.5 3.4 1.6 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF4351 PF14261.1 CDO69918.1 - 0.031 14.1 1.1 0.081 12.8 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) DivIC PF04977.10 CDO69918.1 - 0.031 13.7 6.6 2.8 7.4 2.0 2.5 2 0 0 2 2 2 0 Septum formation initiator End3 PF12761.2 CDO69918.1 - 0.036 13.7 4.0 0.088 12.4 2.7 1.6 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 bZIP_2 PF07716.10 CDO69918.1 - 0.048 13.4 9.0 0.09 12.6 0.0 3.1 2 1 0 3 3 3 0 Basic region leucine zipper TMF_DNA_bd PF12329.3 CDO69918.1 - 0.064 13.0 6.3 4.4 7.1 2.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Surfac_D-trimer PF09006.6 CDO69918.1 - 0.07 12.8 1.2 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation bZIP_1 PF00170.16 CDO69918.1 - 0.09 12.7 7.1 4.1 7.4 0.0 2.7 2 1 0 2 2 2 0 bZIP transcription factor TSC22 PF01166.13 CDO69918.1 - 0.16 11.9 4.3 1.2 9.1 1.5 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4446 PF14584.1 CDO69918.1 - 0.22 11.3 2.2 5.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF904 PF06005.7 CDO69918.1 - 0.3 11.4 5.6 10 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Syntaxin PF00804.20 CDO69918.1 - 0.42 10.8 3.9 1.7 8.8 2.7 2.0 1 1 0 1 1 1 0 Syntaxin Herpes_UL6 PF01763.11 CDO69918.1 - 0.64 8.1 2.4 1.5 6.9 1.7 1.6 1 1 0 1 1 1 0 Herpesvirus UL6 like MAD PF05557.8 CDO69918.1 - 0.73 7.8 6.8 1.3 7.0 4.7 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF1049 PF06305.6 CDO69918.1 - 1.5 8.3 8.1 2.3 7.7 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Striatin PF08232.7 CDO69918.1 - 1.8 8.8 13.7 0.82 9.9 2.8 2.7 2 1 0 3 3 3 0 Striatin family Wbp11 PF09429.5 CDO69918.1 - 2.2 8.2 9.5 17 5.4 0.1 2.4 1 1 1 2 2 2 0 WW domain binding protein 11 Pox_A_type_inc PF04508.7 CDO69918.1 - 4.2 7.4 14.6 6.7 6.7 0.4 4.5 3 2 1 4 4 4 0 Viral A-type inclusion protein repeat DUF2890 PF11081.3 CDO69918.1 - 6.4 6.7 10.0 7.1 6.6 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) HALZ PF02183.13 CDO69918.1 - 8.1 6.2 10.2 2.4 7.9 0.5 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Lactamase_B_2 PF12706.2 CDO69919.1 - 1.4e-18 67.1 0.0 1.7e-17 63.5 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CDO69919.1 - 7.8e-07 28.4 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 CDO69919.1 - 2e-05 24.3 0.9 0.00031 20.4 0.0 2.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily THOC7 PF05615.8 CDO69920.1 - 1.3e-20 74.1 6.9 1.3e-20 74.1 4.8 1.7 1 1 0 1 1 1 1 Tho complex subunit 7 PAM2 PF07145.10 CDO69920.1 - 0.0097 15.3 0.1 0.027 13.9 0.1 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DUF842 PF05811.8 CDO69920.1 - 0.012 15.1 1.0 0.028 13.8 0.2 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DUF342 PF03961.8 CDO69920.1 - 0.032 12.6 6.8 0.047 12.0 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_13 PF13166.1 CDO69920.1 - 0.14 10.6 5.4 0.2 10.0 3.7 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 CDO69920.1 - 0.16 10.8 7.8 0.24 10.3 5.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 CDO69920.1 - 0.5 8.1 3.2 0.69 7.7 2.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4094 PF13334.1 CDO69920.1 - 0.56 10.6 5.5 0.73 10.2 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) CENP-F_leu_zip PF10473.4 CDO69920.1 - 2 8.2 18.6 1.9 8.3 9.5 2.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.1 CDO69920.1 - 2.1 8.8 12.4 7.6 7.0 1.3 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 CDO69920.1 - 3.3 7.3 13.7 0.37 10.4 6.0 1.9 2 0 0 2 2 2 0 Mnd1 family DUF1664 PF07889.7 CDO69920.1 - 3.8 7.3 5.5 3.4 7.4 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 CDO69920.1 - 5.5 6.5 12.6 14 5.2 3.9 2.8 1 1 1 2 2 2 0 Septum formation initiator DUF202 PF02656.10 CDO69921.1 - 9.8e-12 44.9 4.0 9.8e-12 44.9 2.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TctB PF07331.6 CDO69921.1 - 0.011 15.3 4.4 0.028 14.0 0.7 2.1 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Cyt_c_ox_IV PF12270.3 CDO69921.1 - 0.039 13.6 0.1 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF912 PF06024.7 CDO69921.1 - 0.37 10.8 1.9 17 5.5 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2530 PF10745.4 CDO69921.1 - 4 7.4 8.9 7.9 6.5 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) CHCH PF06747.8 CDO69922.1 - 0.0028 17.5 10.0 0.0055 16.5 2.5 2.5 2 0 0 2 2 2 1 CHCH domain DUF2655 PF10848.3 CDO69922.1 - 0.2 11.5 2.9 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2655) DB PF01682.14 CDO69922.1 - 0.33 11.0 5.4 2.1 8.4 2.3 2.0 1 1 1 2 2 2 0 DB module Pet191_N PF10203.4 CDO69922.1 - 2.1 8.4 10.3 24 5.0 7.1 2.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 CDO69922.1 - 9.7 6.2 11.0 0.74 9.8 2.7 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF498 PF04430.9 CDO69924.1 - 1.8e-12 46.8 0.1 2e-08 33.7 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF498/DUF598) BPL_LplA_LipB PF03099.14 CDO69925.1 - 2.3e-18 66.3 0.0 4.8e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 CDO69925.1 - 4.2e-05 23.1 0.0 0.00018 21.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus IFT57 PF10498.4 CDO69925.1 - 0.093 11.4 0.3 0.24 10.0 0.2 1.6 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4218 PF13960.1 CDO69927.1 - 0.00017 20.9 0.1 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF904 PF06005.7 CDO69928.1 - 2.1 8.6 5.1 5 7.4 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) WD40 PF00400.27 CDO69929.1 - 1.5e-40 135.6 35.0 2.7e-10 39.6 1.9 11.8 12 0 0 12 12 12 7 WD domain, G-beta repeat NACHT PF05729.7 CDO69929.1 - 2.6e-08 33.7 0.2 8.9e-08 31.9 0.1 1.9 1 1 0 1 1 1 1 NACHT domain Coatomer_WDAD PF04053.9 CDO69929.1 - 0.00087 18.1 0.0 2.9 6.5 0.0 3.4 3 0 0 3 3 3 2 Coatomer WD associated region AAA_16 PF13191.1 CDO69929.1 - 0.0013 18.7 2.6 0.0031 17.5 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain Nbas_N PF15492.1 CDO69929.1 - 0.0074 15.4 3.6 0.31 10.0 0.1 3.9 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal AAA_22 PF13401.1 CDO69929.1 - 0.074 13.1 0.0 0.26 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain P16-Arc PF04699.9 CDO69932.1 - 1.1e-45 155.4 0.0 1.3e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) WD40 PF00400.27 CDO69933.1 - 2.2e-14 52.6 5.4 4.7e-08 32.6 0.3 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.2 CDO69933.1 - 4.2e-08 32.7 0.1 9.6e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO69933.1 - 8.1e-07 28.5 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 CDO69933.1 - 0.36 10.5 6.7 0.024 14.1 0.9 2.0 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF605 PF04652.11 CDO69933.1 - 6.6 6.0 9.4 11 5.3 6.5 1.2 1 0 0 1 1 1 0 Vta1 like Terpene_synth_C PF03936.11 CDO69934.1 - 1.8e-13 50.3 0.3 2.7e-13 49.7 0.2 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF4064 PF13273.1 CDO69936.1 - 0.032 14.3 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Ni_hydr_CYTB PF01292.15 CDO69936.1 - 0.1 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Sporozoite_P67 PF05642.6 CDO69936.1 - 2.4 5.8 4.9 3.1 5.5 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen p450 PF00067.17 CDO69938.1 - 2.6e-54 184.5 0.0 1.8e-30 105.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF3025 PF11227.3 CDO69938.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3025) DUF3397 PF11877.3 CDO69939.1 - 0.027 14.4 4.3 0.16 11.9 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) Tetraspannin PF00335.15 CDO69939.1 - 0.52 9.5 5.7 1.4 8.1 3.2 2.0 1 1 0 1 1 1 0 Tetraspanin family 7tm_7 PF08395.7 CDO69939.1 - 4.2 6.2 8.3 4.2 6.2 1.0 2.2 2 0 0 2 2 2 0 7tm Chemosensory receptor BPD_transp_1 PF00528.17 CDO69939.1 - 7.7 5.9 13.6 3.8 6.9 0.0 3.0 3 1 0 3 3 3 0 Binding-protein-dependent transport system inner membrane component SNase PF00565.12 CDO69941.1 - 1.5e-16 60.5 0.0 2.4e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue HTH_Tnp_Tc5 PF03221.11 CDO69941.1 - 0.043 13.6 0.0 0.33 10.8 0.0 2.4 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain Flavodoxin_1 PF00258.20 CDO69942.1 - 1.3e-27 96.5 0.0 3.3e-27 95.2 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.15 CDO69942.1 - 1.1e-18 67.4 0.0 1.9e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CDO69942.1 - 7.6e-16 58.6 0.0 1.6e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 CDO69942.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Beta-lactamase PF00144.19 CDO69943.1 - 4.7e-41 140.9 0.5 8e-41 140.1 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 CDO69943.1 - 0.00028 20.6 0.3 0.003 17.3 0.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) SNF2_N PF00176.18 CDO69944.1 - 4.4e-59 199.7 0.3 6.3e-59 199.2 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDO69944.1 - 5e-12 45.5 0.0 1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO69944.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 CDO69944.1 - 0.004 16.9 0.9 0.0077 16.0 0.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CDO69944.1 - 0.032 13.9 2.1 0.093 12.4 1.4 1.8 1 1 0 1 1 1 0 zinc-RING finger domain FYVE PF01363.16 CDO69944.1 - 0.045 13.6 1.2 0.11 12.4 0.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.20 CDO69944.1 - 0.057 13.0 2.0 0.084 12.5 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) cIII PF08134.6 CDO69944.1 - 0.12 12.0 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 cIII protein family TFIIF_alpha PF05793.7 CDO69944.1 - 0.21 9.9 11.8 0.32 9.3 8.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-C3HC4_4 PF15227.1 CDO69944.1 - 0.58 10.0 4.3 0.18 11.7 0.7 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CDO69944.1 - 1.6 8.7 4.0 0.46 10.5 0.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO69944.1 - 2.4 7.8 4.3 6.7 6.4 3.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.20 CDO69945.1 - 1.9e-13 50.6 4.8 5.2e-13 49.2 1.6 2.3 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 CDO69945.1 - 9.3e-09 35.1 1.9 8.8e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CDO69945.1 - 8.6e-08 32.2 0.4 1.2e-07 31.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 CDO69945.1 - 0.00013 21.9 0.6 0.0008 19.3 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_10 PF13460.1 CDO69945.1 - 0.00037 20.5 2.4 0.025 14.5 1.7 2.3 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CDO69945.1 - 0.00045 19.5 0.1 0.00085 18.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CDO69945.1 - 0.0016 17.8 0.3 0.0032 16.9 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO69945.1 - 0.02 13.5 0.0 0.033 12.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CDO69945.1 - 0.043 14.1 0.7 6.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 CDO69947.1 - 3.4e-16 58.9 0.0 5.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO69947.1 - 9.9e-13 47.8 0.1 2.3e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CDO69947.1 - 0.00041 21.2 0.0 0.00067 20.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CDO69948.1 - 9.5e-16 57.5 0.0 1.5e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO69948.1 - 5.1e-12 45.5 0.2 7.8e-11 41.7 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CDO69948.1 - 3.2e-07 31.2 0.0 6.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CDO69948.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding ADH_zinc_N PF00107.21 CDO69949.1 - 1.1e-14 54.1 0.0 1.7e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO69949.1 - 6.9e-11 41.8 0.0 1.5e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Adaptin_N PF01602.15 CDO69950.1 - 4.3e-149 497.2 5.9 5.5e-149 496.8 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CDO69950.1 - 4.3e-25 88.6 2.1 5.2e-23 81.8 0.1 3.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CDO69950.1 - 1.1e-19 70.5 4.6 1.6e-09 37.9 0.0 5.5 1 1 5 6 6 6 6 HEAT repeats HEAT PF02985.17 CDO69950.1 - 8e-07 28.6 17.0 0.00015 21.5 0.1 6.5 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 CDO69950.1 - 9.8e-07 29.0 10.3 0.0027 18.1 0.0 7.2 6 2 3 9 9 9 2 HEAT-like repeat Arm PF00514.18 CDO69950.1 - 2.3e-05 24.0 3.6 0.11 12.4 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 CDO69950.1 - 0.00015 21.2 0.2 0.12 11.6 0.0 3.4 3 1 0 3 3 3 2 CLASP N terminal 2OG-FeII_Oxy_3 PF13640.1 CDO69951.1 - 3.9e-06 27.2 0.2 1.8e-05 25.1 0.0 2.3 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CDO69951.1 - 7.2e-05 23.0 0.0 0.00019 21.6 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNA_pol PF00940.14 CDO69952.1 - 3.7e-164 546.0 0.0 5.4e-164 545.4 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CDO69952.1 - 2.2e-78 263.7 0.4 5.1e-78 262.5 0.3 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 CDO69952.1 - 0.00016 21.5 0.1 0.00059 19.7 0.1 2.1 1 1 0 1 1 1 1 PPR repeat family SPT6_acidic PF14632.1 CDO69952.1 - 6.1 7.0 16.3 13 6.0 11.3 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 SUR7 PF06687.7 CDO69953.1 - 2.3e-13 50.1 19.7 5.3e-12 45.7 13.8 2.5 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CDO69953.1 - 0.006 16.2 9.6 0.012 15.3 6.5 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Histone PF00125.19 CDO69954.1 - 8.5e-23 80.2 0.1 1.2e-22 79.8 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CDO69954.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aldo_ket_red PF00248.16 CDO69955.1 - 3.4e-53 180.3 0.0 4e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 CDO69956.1 - 9.3e-41 139.4 0.0 5.8e-22 77.8 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family IATP PF04568.7 CDO69957.1 - 8e-14 51.4 5.3 9.1e-14 51.2 3.7 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Bap31 PF05529.7 CDO69957.1 - 0.00026 20.5 5.2 0.0003 20.2 3.6 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Atg14 PF10186.4 CDO69957.1 - 0.00064 18.7 4.4 0.00064 18.7 3.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF3573 PF12097.3 CDO69957.1 - 0.00088 17.9 0.5 0.001 17.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) CENP-Q PF13094.1 CDO69957.1 - 0.0024 17.8 7.7 0.0026 17.7 5.3 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Filament PF00038.16 CDO69957.1 - 0.0035 16.8 4.7 0.0041 16.6 3.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein zf-CpG_bind_C PF12269.3 CDO69957.1 - 0.016 14.6 4.8 0.019 14.4 3.3 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain HemX PF04375.9 CDO69957.1 - 0.03 12.9 4.5 0.027 13.0 3.1 1.1 1 0 0 1 1 1 0 HemX IncA PF04156.9 CDO69957.1 - 0.038 13.5 7.9 0.041 13.4 5.5 1.1 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 CDO69957.1 - 0.13 11.9 7.7 0.13 11.8 5.3 1.1 1 0 0 1 1 1 0 Mnd1 family DUF4407 PF14362.1 CDO69957.1 - 0.18 10.7 4.1 0.16 10.8 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YgaB PF14182.1 CDO69957.1 - 0.18 12.0 8.0 0.24 11.6 5.5 1.1 1 0 0 1 1 1 0 YgaB-like protein DUF4140 PF13600.1 CDO69957.1 - 0.19 12.2 3.7 0.24 11.8 2.6 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF342 PF03961.8 CDO69957.1 - 0.2 10.0 3.2 0.19 10.0 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1423 PF07227.6 CDO69957.1 - 0.22 10.1 3.8 0.21 10.1 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) DUF4349 PF14257.1 CDO69957.1 - 0.25 10.5 2.9 0.31 10.2 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DivIC PF04977.10 CDO69957.1 - 0.26 10.7 9.8 0.36 10.3 6.6 1.4 1 1 0 1 1 1 0 Septum formation initiator Mis12 PF05859.7 CDO69957.1 - 0.32 10.7 5.8 0.35 10.6 4.0 1.1 1 0 0 1 1 1 0 Mis12 protein bZIP_Maf PF03131.12 CDO69957.1 - 0.36 11.1 9.6 0.45 10.8 6.7 1.1 1 0 0 1 1 1 0 bZIP Maf transcription factor Prefoldin PF02996.12 CDO69957.1 - 0.39 10.3 6.3 0.68 9.5 4.5 1.5 1 1 0 1 1 1 0 Prefoldin subunit M16C_assoc PF08367.6 CDO69957.1 - 0.6 8.9 9.0 0.75 8.6 6.2 1.0 1 0 0 1 1 1 0 Peptidase M16C associated DP PF08781.5 CDO69957.1 - 0.63 9.7 7.9 0.81 9.3 5.5 1.2 1 0 0 1 1 1 0 Transcription factor DP Spc24 PF08286.6 CDO69957.1 - 0.85 9.3 7.2 0.97 9.1 5.0 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 AAA_23 PF13476.1 CDO69957.1 - 1.3 9.2 8.0 1.5 9.0 5.5 1.0 1 0 0 1 1 1 0 AAA domain DASH_Dad2 PF08654.5 CDO69957.1 - 3.5 7.6 7.3 5 7.1 4.3 1.7 1 1 1 2 2 2 0 DASH complex subunit Dad2 PBP_sp32 PF07222.7 CDO69957.1 - 4.4 6.4 8.0 4.5 6.3 5.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 EAP30 PF04157.11 CDO69957.1 - 9.8 5.2 8.6 12 4.9 5.9 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family ATP_sub_h PF10775.4 CDO69958.1 - 5.2e-23 80.5 1.5 7.8e-23 79.9 1.0 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 CDO69958.1 - 0.018 14.8 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 HEM4 PF02602.10 CDO69959.1 - 2.4e-33 115.3 0.8 3e-33 115.0 0.5 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Apo-CIII PF05778.7 CDO69959.1 - 0.096 12.0 0.4 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) DUF1708 PF08101.6 CDO69960.1 - 5.8e-17 61.6 0.0 5.8e-16 58.3 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) Ribosomal_60s PF00428.14 CDO69960.1 - 0.0087 16.4 1.1 0.0087 16.4 0.8 10.9 5 3 4 9 9 9 1 60s Acidic ribosomal protein RhoGAP PF00620.22 CDO69960.1 - 0.039 13.5 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 RhoGAP domain DUF1628 PF07790.6 CDO69961.1 - 0.0031 18.2 0.1 0.0056 17.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1628) Bac_rhamnosid PF05592.6 CDO69963.1 - 0.0094 14.2 0.0 0.24 9.5 0.0 2.2 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase p450 PF00067.17 CDO69964.1 - 1.9e-32 112.4 0.0 2.7e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Lyase_1 PF00206.15 CDO69964.1 - 1.2e-22 80.5 0.0 1.6e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CDO69964.1 - 1.5e-05 24.9 0.0 5.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus PigN PF04987.9 CDO69965.1 - 3e-96 322.7 18.3 3.7e-96 322.4 12.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CDO69965.1 - 1.9e-12 47.1 0.2 7.1e-10 38.7 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CDO69965.1 - 5.7e-07 29.0 0.0 8.3e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CDO69965.1 - 1.1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DAO PF01266.19 CDO69966.1 - 5.5e-53 180.1 2.6 1.3e-52 178.8 1.8 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CDO69966.1 - 2.1e-06 26.6 0.2 8.8e-06 24.6 0.1 1.8 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.1 CDO69966.1 - 0.0001 22.2 0.1 0.00024 21.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDO69966.1 - 0.00011 22.1 0.4 0.087 12.6 0.3 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO69966.1 - 0.0057 16.4 0.1 0.054 13.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 CDO69966.1 - 0.0073 16.6 0.2 0.0073 16.6 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 CDO69966.1 - 0.069 12.1 0.3 0.17 10.8 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase Thi4 PF01946.12 CDO69966.1 - 0.074 12.1 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.14 CDO69966.1 - 0.09 11.9 0.1 6.6 5.7 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase PS_Dcarbxylase PF02666.10 CDO69967.1 - 4.5e-41 140.3 0.0 6.9e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 CDO69967.1 - 2.8e-35 120.9 0.0 4.6e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase SRP9-21 PF05486.7 CDO69968.1 - 1.2e-19 69.8 0.2 1.6e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Mito_carr PF00153.22 CDO69969.1 - 1.3e-51 172.2 0.9 7.5e-17 60.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Glug PF07581.7 CDO69969.1 - 0.12 12.5 0.9 1.4 9.2 0.1 2.6 2 0 0 2 2 2 0 The GLUG motif PT-VENN PF04829.8 CDO69969.1 - 0.3 10.6 2.0 7.3 6.2 0.0 2.9 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif adh_short PF00106.20 CDO69970.1 - 4.3e-06 26.7 2.4 0.00024 21.0 1.7 2.3 1 1 0 1 1 1 1 short chain dehydrogenase UQ_con PF00179.21 CDO69971.1 - 9.5e-39 132.0 0.0 1.4e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme OTU PF02338.14 CDO69973.1 - 7.6e-16 58.7 0.0 1.5e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CDO69973.1 - 0.034 13.4 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain adh_short PF00106.20 CDO69974.1 - 5.8e-16 58.8 0.2 6.5e-16 58.6 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO69974.1 - 1.3e-07 31.4 0.2 2.3e-07 30.6 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO69974.1 - 1.4e-05 24.6 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO69974.1 - 0.0012 18.9 0.2 0.0016 18.5 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CDO69974.1 - 0.0018 18.0 0.1 0.0036 17.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 CDO69974.1 - 0.052 13.2 0.0 0.06 13.1 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 CDO69974.1 - 0.085 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CDO69974.1 - 0.094 11.5 0.0 0.16 10.8 0.0 1.3 1 1 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 CDO69974.1 - 0.11 11.7 0.5 0.78 8.9 0.4 1.8 1 1 1 2 2 2 0 NmrA-like family adh_short PF00106.20 CDO69975.1 - 1.6e-23 83.4 1.4 3.7e-23 82.2 0.8 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO69975.1 - 2e-13 50.6 0.0 3.8e-13 49.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO69975.1 - 5.3e-11 42.5 0.5 1.1e-10 41.4 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO69975.1 - 3.3e-05 23.4 0.0 5.5e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO69975.1 - 0.0028 17.6 0.3 0.0082 16.1 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CDO69975.1 - 0.0064 16.2 1.1 0.011 15.4 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 CDO69975.1 - 0.0082 15.3 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Pkinase PF00069.20 CDO69976.1 - 3.5e-69 232.8 0.0 5.1e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO69976.1 - 9.4e-38 129.7 0.0 1.5e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO69976.1 - 1.4e-05 24.2 0.0 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CDO69976.1 - 0.0093 15.3 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CDO69976.1 - 0.047 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family KA1 PF02149.14 CDO69977.1 - 0.05 13.0 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase associated domain 1 CNH PF00780.17 CDO69978.1 - 1.2e-47 162.6 0.0 1.6e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 CNH domain PH PF00169.24 CDO69978.1 - 0.00092 19.3 0.1 0.0053 16.9 0.1 2.2 2 1 0 2 2 2 1 PH domain Neur PF00064.13 CDO69978.1 - 0.15 10.1 0.0 0.22 9.5 0.0 1.2 1 0 0 1 1 1 0 Neuraminidase zf-H2C2 PF09337.5 CDO69979.1 - 0.0032 16.8 0.5 0.0059 15.9 0.3 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Mito_carr PF00153.22 CDO69980.1 - 2.1e-67 222.8 3.2 2.1e-22 78.6 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_28 PF00295.12 CDO69980.1 - 9.8e-28 97.0 0.7 8.1e-27 94.0 0.5 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Tim17 PF02466.14 CDO69980.1 - 0.012 15.6 0.1 18 5.3 0.0 3.8 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_S19 PF00203.16 CDO69981.1 - 3.2e-24 84.3 0.0 4e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 GspH PF12019.3 CDO69984.1 - 0.069 13.2 4.9 3.4 7.8 0.2 3.7 2 2 1 3 3 3 0 Type II transport protein GspH DUF3584 PF12128.3 CDO69984.1 - 3.7 4.7 17.8 4.9 4.3 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ribosomal_S19 PF00203.16 CDO69985.1 - 3.2e-24 84.3 0.0 4e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 STE3 PF02076.10 CDO69987.1 - 4.1e-99 331.2 17.5 4.9e-99 330.9 12.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 CDO69988.1 - 5.1e-69 232.5 22.1 1.2e-48 165.6 5.1 2.0 1 1 1 2 2 2 2 Pheromone A receptor Pro_CA PF00484.14 CDO69989.1 - 7.8e-12 45.4 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase MIP PF00230.15 CDO69991.1 - 7.8e-51 172.7 7.2 1e-50 172.3 5.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein PAP2 PF01569.16 CDO69991.1 - 3.5 7.3 9.7 0.088 12.4 1.1 2.5 3 1 0 3 3 3 0 PAP2 superfamily FliJ PF02050.11 CDO69992.1 - 0.031 14.3 9.6 0.46 10.5 2.4 2.7 2 0 0 2 2 2 0 Flagellar FliJ protein DUF904 PF06005.7 CDO69992.1 - 0.26 11.6 4.0 0.8 10.0 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 CDO69992.1 - 1 9.2 8.7 0.078 12.7 2.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BMFP PF04380.8 CDO69992.1 - 7.9 6.7 12.5 4.9 7.3 0.9 3.2 2 1 0 2 2 2 0 Membrane fusogenic activity OGFr_N PF04664.8 CDO69993.1 - 1.5e-56 191.1 2.0 1.8e-56 190.8 1.4 1.0 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region DUF1491 PF07372.7 CDO69993.1 - 0.0025 17.7 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1491) DUF727 PF05303.7 CDO69995.1 - 5.2e-05 23.0 0.1 0.00014 21.6 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF727) Sec1 PF00995.18 CDO69996.1 - 2.5e-138 462.2 0.0 2.9e-138 462.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.7 CDO69997.1 - 5.5e-69 232.1 0.2 1.5e-68 230.7 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CDO69997.1 - 2.5e-31 107.4 0.3 2.5e-31 107.4 0.2 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3413 PF11893.3 CDO69998.1 - 6.3 5.5 12.6 1.5 7.6 4.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) E1-E2_ATPase PF00122.15 CDO69999.1 - 6.2e-14 51.5 0.0 6.2e-14 51.5 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 CDO69999.1 - 2.3e-13 50.7 0.2 1.2e-12 48.3 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDO69999.1 - 1e-11 45.6 3.0 6.1e-07 30.0 0.4 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDO69999.1 - 3.1e-11 43.0 0.0 1.1e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CDO69999.1 - 0.00021 20.9 1.3 0.004 16.7 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CDO69999.1 - 0.022 15.0 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HTH_21 PF13276.1 CDO70000.1 - 0.00028 20.8 0.1 0.00065 19.6 0.0 1.7 2 0 0 2 2 2 1 HTH-like domain DDE_Tnp_ISAZ013 PF07592.6 CDO70000.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain RecX PF02631.11 CDO70000.1 - 0.21 11.7 1.1 0.31 11.2 0.1 1.7 2 0 0 2 2 2 0 RecX family Pkinase PF00069.20 CDO70001.1 - 1.4e-09 37.4 0.0 3.8e-09 36.0 0.0 1.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70001.1 - 0.0046 16.0 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3506 PF12014.3 CDO70002.1 - 1.9e-07 30.9 0.0 1.4e-05 24.8 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.28 CDO70002.1 - 3.4e-06 26.5 0.8 9.3e-06 25.1 0.6 1.8 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO70002.1 - 4.6e-05 23.0 0.6 4.6e-05 23.0 0.4 1.9 2 0 0 2 2 2 1 F-box-like Elongin_A PF06881.6 CDO70002.1 - 0.07 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-RING_2 PF13639.1 CDO70003.1 - 0.0023 17.7 0.3 2.1 8.2 0.0 2.4 2 0 0 2 2 2 2 Ring finger domain Pam17 PF08566.5 CDO70004.1 - 9.1e-66 220.8 0.0 1.1e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 ABC_transp_aux PF09822.4 CDO70005.1 - 0.098 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system F-box-like PF12937.2 CDO70005.1 - 0.2 11.3 2.2 0.51 10.1 1.5 1.7 1 0 0 1 1 1 0 F-box-like ATP-synt_ab PF00006.20 CDO70006.1 - 2.8e-63 213.2 0.0 4.5e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CDO70006.1 - 2.1e-26 92.5 0.4 3.6e-26 91.8 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CDO70006.1 - 1.9e-22 79.2 2.0 5e-22 77.8 1.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.17 CDO70006.1 - 0.0056 15.5 0.7 0.03 13.1 0.1 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 CDO70006.1 - 0.017 14.5 0.0 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CDO70006.1 - 0.017 14.7 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 CDO70006.1 - 0.025 14.7 0.0 0.28 11.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CDO70006.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 CDO70006.1 - 0.029 14.5 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CDO70006.1 - 0.033 13.2 0.1 0.056 12.5 0.1 1.4 1 0 0 1 1 1 0 KaiC MobB PF03205.9 CDO70006.1 - 0.043 13.5 0.1 2 8.1 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CDO70006.1 - 0.047 12.8 0.1 0.079 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CDO70006.1 - 0.053 13.4 0.4 0.15 12.0 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain GATase_2 PF00310.16 CDO70007.1 - 4.9e-25 87.9 0.1 1.3e-18 66.8 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II SNF2_N PF00176.18 CDO70007.1 - 6.2e-23 81.0 0.0 3.1e-18 65.5 0.0 2.7 1 1 1 2 2 2 2 SNF2 family N-terminal domain Pribosyltran PF00156.22 CDO70007.1 - 2e-14 53.4 0.4 4.4e-14 52.2 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_6 PF13522.1 CDO70007.1 - 1.2e-13 51.1 0.0 2.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CDO70007.1 - 1.1e-11 44.5 0.0 2.2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Helicase_C PF00271.26 CDO70007.1 - 1.3e-06 28.1 0.3 5.1e-06 26.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GATase_4 PF13230.1 CDO70007.1 - 1.1e-05 24.3 0.0 2.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Septin PF00735.13 CDO70008.1 - 1.8e-115 384.8 0.8 2.2e-115 384.5 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CDO70008.1 - 5.1e-08 32.8 0.0 2.3e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 CDO70008.1 - 2.4e-06 26.8 0.0 4.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 CDO70008.1 - 2.3e-05 23.6 0.0 4.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CDO70008.1 - 5.9e-05 22.5 0.3 0.0027 17.1 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CDO70008.1 - 6.4e-05 22.8 0.6 0.093 12.5 0.1 2.4 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 CDO70008.1 - 0.0002 20.9 0.0 0.00024 20.6 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain FtsK_SpoIIIE PF01580.13 CDO70008.1 - 0.00045 19.7 0.0 0.00089 18.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 CDO70008.1 - 0.00093 18.1 0.0 0.0019 17.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.17 CDO70008.1 - 0.0048 15.7 0.1 0.0095 14.8 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 CDO70008.1 - 0.0071 16.3 0.0 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 CDO70008.1 - 0.0073 16.6 2.0 0.011 15.9 1.4 1.7 1 1 0 1 1 1 1 ABC transporter IIGP PF05049.8 CDO70008.1 - 0.011 14.5 0.2 0.034 12.9 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Gtr1_RagA PF04670.7 CDO70008.1 - 0.013 14.7 0.1 0.067 12.3 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 CDO70008.1 - 0.025 14.4 0.2 0.24 11.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CDO70008.1 - 0.027 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CDO70008.1 - 0.029 14.5 0.0 0.069 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 CDO70008.1 - 0.039 14.4 0.1 0.1 13.0 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein DUF815 PF05673.8 CDO70008.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MobB PF03205.9 CDO70008.1 - 0.1 12.3 0.1 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CDO70008.1 - 0.1 12.9 1.2 0.23 11.7 0.9 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CDO70008.1 - 0.19 12.5 0.6 0.76 10.5 0.4 2.2 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 CDO70008.1 - 0.24 11.2 1.9 0.32 10.7 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 F-box-like PF12937.2 CDO70009.1 - 0.00051 19.7 1.3 0.0015 18.2 0.9 1.9 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 CDO70010.1 - 2e-32 112.4 0.0 3.4e-32 111.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70010.1 - 7e-05 22.0 0.0 0.13 11.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CDO70010.1 - 0.071 12.8 1.4 2.2 7.9 0.2 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.27 CDO70011.1 - 2.2e-31 106.5 12.8 3.1e-05 23.6 0.4 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 CDO70011.1 - 5e-17 61.3 1.8 5e-17 61.3 1.3 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 CDO70011.1 - 2.4e-11 42.9 1.2 2.4e-11 42.9 0.8 2.7 3 0 0 3 3 3 1 F-box domain Nup160 PF11715.3 CDO70011.1 - 2.4e-06 26.0 3.0 0.29 9.2 0.2 3.4 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Terpene_synth_C PF03936.11 CDO70012.1 - 1.1e-08 34.6 0.0 1.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SH3_9 PF14604.1 CDO70013.1 - 5.9e-11 41.7 0.0 1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CDO70013.1 - 2.8e-06 26.5 0.0 4.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CDO70013.1 - 2.9e-05 23.4 0.0 5.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Herpes_gE PF02480.11 CDO70013.1 - 2.5 6.2 4.7 0.93 7.6 0.2 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E AAA_5 PF07728.9 CDO70014.1 - 3e-07 30.2 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CDO70014.1 - 0.00017 21.5 0.0 0.00038 20.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CDO70014.1 - 0.0019 18.3 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDO70014.1 - 0.0031 17.5 0.0 0.0096 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 CDO70014.1 - 0.026 14.3 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDO70014.1 - 0.031 15.1 0.0 0.06 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CDO70014.1 - 0.041 13.0 0.0 0.099 11.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CDO70014.1 - 0.049 13.0 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 CDO70014.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CDO70014.1 - 0.29 11.3 0.0 0.56 10.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Aha1_N PF09229.6 CDO70015.1 - 1.5e-16 60.4 0.0 3.4e-16 59.3 0.0 1.5 1 1 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CDO70015.1 - 1.4e-13 51.0 0.3 3.3e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 CDO70015.1 - 9.6e-05 22.5 6.4 0.00011 22.4 0.2 2.3 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport DUF3429 PF11911.3 CDO70016.1 - 7.8e-36 123.1 12.5 1.1e-35 122.7 8.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) SKG6 PF08693.5 CDO70017.1 - 0.0043 16.3 0.2 0.012 14.9 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1370 PF07114.6 CDO70017.1 - 5 6.2 8.0 0.43 9.7 2.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1370) HET PF06985.6 CDO70018.1 - 4.9e-10 39.7 1.3 2.4e-06 27.7 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF836 PF05768.9 CDO70019.1 - 6.1e-11 42.4 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) PSP PF04046.11 CDO70019.1 - 6.1e-07 28.7 0.4 2e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 PSP zf-CCHC PF00098.18 CDO70019.1 - 0.0018 18.0 0.2 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Thioredoxin_3 PF13192.1 CDO70019.1 - 0.002 17.8 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain IF-2B PF01008.12 CDO70021.1 - 6.7e-68 228.7 0.0 8e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family G-gamma PF00631.17 CDO70022.1 - 7.5e-15 54.4 0.1 9.6e-15 54.0 0.0 1.1 1 0 0 1 1 1 1 GGL domain FA PF08736.6 CDO70022.1 - 0.067 12.9 0.5 0.11 12.2 0.4 1.4 1 0 0 1 1 1 0 FERM adjacent (FA) DUF4200 PF13863.1 CDO70023.1 - 0.043 13.7 0.9 0.043 13.7 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2508 PF10704.4 CDO70023.1 - 0.11 12.7 1.6 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Tantalus PF15386.1 CDO70023.1 - 0.19 11.4 1.7 0.56 10.0 0.3 2.1 2 0 0 2 2 2 0 Drosophila Tantalus-like DDE_3 PF13358.1 CDO70024.1 - 6.7e-16 58.3 0.4 7.4e-16 58.2 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO70024.1 - 0.0038 17.3 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain GST_N_3 PF13417.1 CDO70025.1 - 1.3e-13 50.9 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO70025.1 - 3.5e-08 33.3 0.0 1.3e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO70025.1 - 0.00018 21.5 0.0 0.00065 19.8 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO70025.1 - 0.011 15.6 0.3 0.026 14.3 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ATP_bind_1 PF03029.12 CDO70026.1 - 1.2e-71 240.9 0.0 1.5e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 CDO70026.1 - 0.069 13.0 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDO70026.1 - 0.13 13.0 7.4 0.056 14.2 1.8 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CDO70026.1 - 0.19 11.6 0.7 1.9 8.4 0.5 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DDE_3 PF13358.1 CDO70027.1 - 2.1e-16 59.9 0.4 2.2e-16 59.9 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO70027.1 - 0.0012 18.9 0.0 0.0014 18.7 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Taeniidae_ag PF05596.6 CDO70028.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Taeniidae antigen HMG_box_2 PF09011.5 CDO70030.1 - 1.6e-05 25.1 0.6 3.7e-05 24.0 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 CDO70030.1 - 6.8e-05 23.0 0.9 0.00037 20.6 0.3 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box DUF4356 PF14266.1 CDO70030.1 - 0.021 13.2 0.1 0.031 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4356) DrsE_2 PF13686.1 CDO70030.1 - 0.065 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family SieB PF14163.1 CDO70030.1 - 0.29 10.6 2.0 0.42 10.1 0.1 2.0 2 0 0 2 2 2 0 Superinfection exclusion protein B PBP1_TM PF14812.1 CDO70032.1 - 0.003 17.8 0.4 0.0053 17.0 0.3 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 CDO70032.1 - 2.4 7.6 5.8 4 6.9 4.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Velvet PF11754.3 CDO70033.1 - 1.6e-14 54.0 0.0 2.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Velvet factor zf-RVT PF13966.1 CDO70034.1 - 0.00032 20.9 0.0 0.00052 20.2 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase UBN2_2 PF14227.1 CDO70035.1 - 3.5e-12 45.9 0.0 1.3e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO70035.1 - 1e-07 31.7 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Med19 PF10278.4 CDO70035.1 - 0.15 11.7 4.0 0.35 10.5 2.7 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 MIP-T3 PF10243.4 CDO70036.1 - 0.0015 17.0 12.9 0.0025 16.3 8.9 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 CDO70036.1 - 0.0027 15.8 6.5 0.0038 15.3 4.5 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.5 CDO70036.1 - 0.0084 15.2 13.1 0.017 14.2 9.1 1.5 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 CDO70036.1 - 0.048 11.5 17.9 0.069 11.0 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CDO70036.1 - 2.1 6.7 25.1 3.7 5.9 17.4 1.3 1 0 0 1 1 1 0 Daxx Family Mpp10 PF04006.7 CDO70036.1 - 2.9 6.1 19.5 4.2 5.6 13.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Cauli_VI PF01693.11 CDO70038.1 - 1.2e-10 41.2 0.1 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Amidase_5 PF05382.8 CDO70040.1 - 0.078 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase DUF755 PF05501.6 CDO70042.1 - 0.017 15.1 7.7 0.021 14.8 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CENP-Q PF13094.1 CDO70042.1 - 0.15 12.1 15.9 0.17 11.8 11.0 1.0 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SPX PF03105.14 CDO70042.1 - 0.31 10.7 7.8 0.34 10.6 5.4 1.0 1 0 0 1 1 1 0 SPX domain TSA PF03249.8 CDO70042.1 - 0.48 8.9 7.9 0.53 8.7 5.5 1.0 1 0 0 1 1 1 0 Type specific antigen DUF3619 PF12279.3 CDO70042.1 - 0.52 10.3 4.4 0.61 10.1 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF972 PF06156.8 CDO70042.1 - 0.52 10.6 11.7 0.61 10.4 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Caldesmon PF02029.10 CDO70042.1 - 0.6 8.4 20.4 0.63 8.4 14.2 1.0 1 0 0 1 1 1 0 Caldesmon U79_P34 PF03064.11 CDO70042.1 - 0.61 9.5 12.4 0.63 9.5 8.6 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MCPVI PF02993.9 CDO70042.1 - 0.7 10.0 9.6 0.76 9.8 6.6 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DUF1664 PF07889.7 CDO70042.1 - 0.76 9.5 4.0 0.78 9.5 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PP31 PF05311.6 CDO70042.1 - 0.76 8.9 10.3 0.86 8.8 7.2 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) YlqD PF11068.3 CDO70042.1 - 0.98 9.4 14.7 1.2 9.1 10.2 1.1 1 0 0 1 1 1 0 YlqD protein DUF3449 PF11931.3 CDO70042.1 - 1.2 8.6 10.1 1.5 8.3 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) FAM60A PF15396.1 CDO70042.1 - 1.2 8.7 6.8 1.3 8.7 4.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Vfa1 PF08432.5 CDO70042.1 - 1.7 8.6 17.1 1.9 8.4 11.9 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Herpes_UL6 PF01763.11 CDO70042.1 - 1.9 6.5 7.4 2.2 6.3 5.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF1266 PF06889.6 CDO70042.1 - 2 8.2 8.8 2.3 7.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF1764 PF08576.5 CDO70042.1 - 2 9.2 10.6 3.2 8.5 7.3 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CDC45 PF02724.9 CDO70042.1 - 2.4 6.1 12.0 3.5 5.5 8.3 1.3 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 CDO70042.1 - 2.8 7.9 12.1 3.3 7.7 8.4 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF2413 PF10310.4 CDO70042.1 - 2.9 6.5 16.2 3.6 6.3 11.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3584 PF12128.3 CDO70042.1 - 3.4 4.8 15.4 3.5 4.8 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Peptidase_S49_N PF08496.5 CDO70042.1 - 3.4 7.4 10.6 4 7.2 7.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DDRGK PF09756.4 CDO70042.1 - 3.5 6.9 21.4 3.9 6.8 14.8 1.1 1 0 0 1 1 1 0 DDRGK domain NARP1 PF12569.3 CDO70042.1 - 3.7 6.1 17.5 4.3 5.9 12.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ax_dynein_light PF10211.4 CDO70042.1 - 3.8 7.3 14.6 4.2 7.1 10.1 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain EMP24_GP25L PF01105.19 CDO70042.1 - 4.2 7.0 6.5 5.3 6.7 4.5 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD STAG PF08514.6 CDO70042.1 - 4.4 7.0 7.4 5.8 6.6 5.2 1.3 1 0 0 1 1 1 0 STAG domain DUF2968 PF11180.3 CDO70042.1 - 4.6 6.5 15.5 5.5 6.3 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) IncA PF04156.9 CDO70042.1 - 4.9 6.7 17.4 6 6.4 12.1 1.1 1 0 0 1 1 1 0 IncA protein GBP_C PF02841.9 CDO70042.1 - 5.3 6.1 15.3 5.6 6.0 10.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain FLO_LFY PF01698.11 CDO70042.1 - 6.8 5.4 10.6 6.9 5.3 7.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein ATP11 PF06644.6 CDO70042.1 - 6.8 6.0 14.2 7.5 5.9 9.8 1.0 1 0 0 1 1 1 0 ATP11 protein Lge1 PF11488.3 CDO70042.1 - 7.2 6.8 9.8 9.7 6.4 5.9 1.9 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 COG2 PF06148.6 CDO70042.1 - 7.7 6.3 8.5 9.1 6.1 5.9 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FYDLN_acid PF09538.5 CDO70042.1 - 7.8 7.1 13.8 11 6.7 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SAPS PF04499.10 CDO70042.1 - 8.4 4.8 11.1 8.9 4.8 7.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein F-protein PF00469.15 CDO70042.1 - 9.4 5.5 8.0 11 5.3 5.5 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef BTV_NS2 PF04514.7 CDO70042.1 - 9.5 4.9 15.5 11 4.8 10.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HAUS6_N PF14661.1 CDO70042.1 - 9.5 5.4 12.7 10 5.3 8.8 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus BSMAP PF12280.3 CDO70042.1 - 9.7 6.0 7.2 12 5.7 5.0 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein GAGA_bind PF06217.7 CDO70042.1 - 9.8 6.0 9.7 10 5.9 6.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family EFG_IV PF03764.13 CDO70044.1 - 9.4e-34 115.5 0.1 8.9e-33 112.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 CDO70044.1 - 4.7e-30 103.2 0.0 1e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CDO70044.1 - 1.3e-22 79.4 0.0 2.9e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CDO70044.1 - 3.5e-13 49.4 0.0 8.6e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.22 CDO70044.1 - 2.9e-08 33.3 0.0 5.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF1367 PF07105.6 CDO70044.1 - 0.032 13.6 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) GTP_EFTU PF00009.22 CDO70045.1 - 2.1e-24 86.0 0.1 2.6e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain S1-P1_nuclease PF02265.11 CDO70046.1 - 7.7e-54 182.9 0.0 5.8e-52 176.8 0.0 2.6 1 1 0 1 1 1 1 S1/P1 Nuclease WD40 PF00400.27 CDO70048.1 - 3.2e-48 159.9 18.3 5.2e-11 41.9 0.3 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CDO70048.1 - 0.0072 16.0 9.0 6.9 6.3 0.0 4.3 2 2 1 4 4 4 3 Transcription factor IIIC subunit delta N-term DUF3567 PF12091.3 CDO70048.1 - 0.15 12.0 0.0 19 5.3 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3567) PIF1 PF05970.9 CDO70049.1 - 5.6e-51 173.5 0.2 5.7e-42 143.9 0.0 2.7 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CDO70049.1 - 2.4e-18 66.4 0.0 4.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CDO70049.1 - 5.5e-08 33.0 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO70049.1 - 2e-07 30.6 0.1 6.8e-07 28.9 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CDO70049.1 - 1.4e-05 25.1 0.2 0.00012 22.0 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.13 CDO70049.1 - 2.6e-05 23.8 0.3 0.0043 16.6 0.1 3.3 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 CDO70049.1 - 0.00013 21.6 0.0 0.57 9.7 0.0 2.4 1 1 0 2 2 2 2 AAA domain T2SE PF00437.15 CDO70049.1 - 0.00016 20.6 0.0 0.00031 19.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.9 CDO70049.1 - 0.00034 20.3 0.0 0.0012 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CDO70049.1 - 0.00055 19.3 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 CDO70049.1 - 0.0012 18.5 0.2 0.012 15.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Herpes_Helicase PF02689.9 CDO70049.1 - 0.0017 16.1 0.3 0.066 10.9 0.0 2.6 2 1 1 3 3 3 1 Helicase UvrD_C_2 PF13538.1 CDO70049.1 - 0.0018 18.3 0.0 0.01 15.9 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 CDO70049.1 - 0.0022 17.2 0.0 0.0047 16.1 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein Mg_chelatase PF01078.16 CDO70049.1 - 0.0057 15.8 0.0 0.0089 15.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 CDO70049.1 - 0.0081 15.3 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CDO70049.1 - 0.012 15.9 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 CDO70049.1 - 0.021 14.2 0.1 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 CDO70049.1 - 0.029 13.3 0.0 0.049 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 CDO70049.1 - 0.042 13.7 0.0 0.19 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CDO70049.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.4 CDO70049.1 - 0.049 12.2 0.0 0.08 11.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Helicase_RecD PF05127.9 CDO70049.1 - 0.051 13.2 0.2 0.16 11.6 0.1 1.8 1 1 0 1 1 1 0 Helicase Zot PF05707.7 CDO70049.1 - 0.056 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Arch_ATPase PF01637.13 CDO70049.1 - 0.063 12.9 0.1 0.38 10.4 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 CDO70049.1 - 0.069 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 CDO70049.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NeA_P2 PF12312.3 CDO70050.1 - 0.12 11.5 0.6 0.22 10.7 0.4 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein zf-C3HC4_2 PF13923.1 CDO70051.1 - 3.8e-06 26.8 4.8 7.1e-06 25.9 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO70051.1 - 0.0014 18.3 5.9 0.0018 17.8 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO70051.1 - 0.0061 16.3 1.4 0.0061 16.3 0.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-TFIIIC PF12660.2 CDO70051.1 - 0.016 15.0 4.5 0.033 14.1 1.8 2.3 2 1 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex zf-C3HC4 PF00097.20 CDO70051.1 - 0.024 14.2 2.0 0.024 14.2 1.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Bindin PF02084.10 CDO70051.1 - 0.071 13.1 0.5 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Bindin NAP PF00956.13 CDO70051.1 - 0.086 11.9 1.0 0.13 11.3 0.7 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) DUF2318 PF10080.4 CDO70051.1 - 0.18 11.5 1.2 0.77 9.5 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Atg14 PF10186.4 CDO70051.1 - 0.28 10.0 4.5 0.43 9.4 3.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C3HC4_4 PF15227.1 CDO70051.1 - 0.52 10.2 5.6 0.12 12.2 0.9 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CDO70051.1 - 7.2 6.4 7.5 18 5.1 2.6 2.6 2 1 0 2 2 2 0 zinc-RING finger domain DUF302 PF03625.9 CDO70052.1 - 1.3e-06 27.9 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF302 Spt5-NGN PF03439.8 CDO70054.1 - 1e-22 79.6 0.0 2.4e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 CDO70054.1 - 3.7e-17 61.2 31.6 8.1e-07 28.5 0.1 8.3 9 0 0 9 9 9 5 KOW motif Spt5_N PF11942.3 CDO70054.1 - 5e-12 46.2 16.3 5e-12 46.2 11.3 3.3 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 CDO70054.1 - 1.4e-07 31.9 33.7 4e-07 30.4 23.2 1.8 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 YajC PF02699.10 CDO70054.1 - 0.075 12.7 2.4 0.11 12.1 0.3 2.4 2 1 0 2 2 2 0 Preprotein translocase subunit UvdE PF03851.9 CDO70055.1 - 8.1e-89 297.3 0.0 1.1e-88 296.9 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF543 PF04418.7 CDO70056.1 - 1.1e-28 98.9 0.3 1.3e-28 98.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-C2HC_2 PF13913.1 CDO70056.1 - 0.17 11.6 0.2 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type HET PF06985.6 CDO70057.1 - 3.2e-08 33.8 0.2 6.5e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Herpes_UL45 PF05473.7 CDO70057.1 - 0.18 11.2 0.3 0.33 10.3 0.2 1.3 1 0 0 1 1 1 0 UL45 protein RVT_1 PF00078.22 CDO70062.1 - 2.1e-13 50.1 0.0 3.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO70062.1 - 2.3e-12 47.3 0.0 3.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO70062.1 - 0.0018 18.5 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase BH3 PF15285.1 CDO70062.1 - 0.086 12.3 0.2 0.3 10.6 0.1 2.0 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Velvet PF11754.3 CDO70068.1 - 7.6e-22 77.9 0.0 3.6e-21 75.6 0.0 1.9 1 1 0 1 1 1 1 Velvet factor MoCF_biosynth PF00994.19 CDO70069.1 - 1.6e-29 102.1 0.0 2.5e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain GPI-anchored PF10342.4 CDO70070.1 - 1.7e-12 47.6 1.7 1.7e-12 47.6 1.2 2.1 1 1 2 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RAP1 PF07218.6 CDO70070.1 - 9 4.2 12.7 10 4.0 8.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.20 CDO70071.1 - 1.3e-06 27.7 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SYF2 PF08231.7 CDO70072.1 - 1.1e-48 165.1 12.8 1.1e-48 165.1 8.9 2.4 1 1 1 2 2 2 1 SYF2 splicing factor SAE2 PF08573.5 CDO70073.1 - 6.3e-19 68.4 1.8 6.3e-19 68.4 1.2 3.2 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus IncA PF04156.9 CDO70073.1 - 0.028 14.0 15.8 0.071 12.6 11.0 1.8 1 0 0 1 1 1 0 IncA protein FUSC PF04632.7 CDO70073.1 - 5.8 5.2 7.8 9.9 4.4 5.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family EAP30 PF04157.11 CDO70076.1 - 0.004 16.3 0.9 0.0083 15.3 0.6 1.5 1 0 0 1 1 1 1 EAP30/Vps36 family DUF2383 PF09537.5 CDO70076.1 - 0.022 15.0 1.4 0.056 13.6 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DUF1840 PF08895.6 CDO70076.1 - 0.053 13.5 0.1 0.053 13.5 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) DUF1319 PF07028.6 CDO70076.1 - 0.088 12.9 7.1 0.19 11.9 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) GrpE PF01025.14 CDO70076.1 - 0.75 9.3 10.8 1.6 8.2 4.3 2.6 3 0 0 3 3 3 0 GrpE Fib_alpha PF08702.5 CDO70076.1 - 0.92 9.6 7.9 3.7 7.6 5.5 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Mst1_SARAH PF11629.3 CDO70076.1 - 0.96 9.3 6.0 4.7 7.1 1.7 2.8 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 AAA_23 PF13476.1 CDO70076.1 - 1 9.6 6.4 0.12 12.6 1.4 1.6 2 0 0 2 2 2 0 AAA domain Oxysterol_BP PF01237.13 CDO70076.1 - 1.6 7.1 8.2 0.7 8.3 1.8 2.0 2 0 0 2 2 2 0 Oxysterol-binding protein DUF3186 PF11382.3 CDO70076.1 - 1.7 7.7 7.0 1 8.4 2.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3186) Cluap1 PF10234.4 CDO70076.1 - 1.7 7.7 10.5 2.8 7.0 7.3 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 APG6 PF04111.7 CDO70076.1 - 1.8 7.5 13.0 3 6.8 8.5 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 CDO70076.1 - 1.8 6.8 5.7 2.6 6.3 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Prominin PF05478.6 CDO70076.1 - 1.8 5.9 4.9 2.4 5.5 3.4 1.1 1 0 0 1 1 1 0 Prominin Prefoldin PF02996.12 CDO70076.1 - 2.7 7.6 8.6 0.31 10.6 2.9 1.7 2 0 0 2 2 2 0 Prefoldin subunit DUF3391 PF11871.3 CDO70076.1 - 5.1 7.3 9.0 1 9.5 2.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) U1snRNP70_N PF12220.3 CDO70076.1 - 5.8 7.3 8.8 10 6.4 1.2 2.7 3 0 0 3 3 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Lge1 PF11488.3 CDO70076.1 - 6.2 7.0 14.4 1e+02 3.2 7.7 3.2 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 TBPIP PF07106.8 CDO70076.1 - 7.7 6.0 11.6 1.5 8.3 3.3 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DnaJ PF00226.26 CDO70078.1 - 8.9e-20 70.2 0.1 3.1e-19 68.4 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain VIT1 PF01988.14 CDO70078.1 - 0.18 11.2 0.0 0.58 9.5 0.0 1.8 1 0 0 1 1 1 0 VIT family DUF342 PF03961.8 CDO70078.1 - 7.9 4.7 6.7 12 4.2 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Synaptobrevin PF00957.16 CDO70079.1 - 6.8e-35 118.5 4.3 7.8e-35 118.3 3.0 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.1 CDO70079.1 - 0.003 16.2 0.8 0.0035 16.0 0.5 1.0 1 0 0 1 1 1 1 TMEM117 protein family DUF515 PF04415.7 CDO70079.1 - 0.04 12.1 0.4 0.043 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Shisa PF13908.1 CDO70079.1 - 0.065 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pkinase PF00069.20 CDO70081.1 - 3.6e-74 249.1 0.0 6e-74 248.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70081.1 - 1.4e-41 142.2 0.0 2e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO70081.1 - 1.2e-11 44.1 0.0 1.8e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDO70081.1 - 0.001 18.1 0.1 0.0022 17.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Toxin_42 PF15522.1 CDO70081.1 - 0.043 13.0 0.3 0.085 12.0 0.2 1.4 1 0 0 1 1 1 0 Putative toxin 42 GLE1 PF07817.8 CDO70082.1 - 7.3e-34 116.8 0.1 3.3e-33 114.6 0.0 2.0 2 0 0 2 2 2 1 GLE1-like protein HTH_31 PF13560.1 CDO70084.1 - 1.2e-07 31.7 0.0 1.5e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 CDO70084.1 - 1.3e-07 31.2 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 CDO70084.1 - 1.1e-05 25.3 0.0 1.3e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CDO70084.1 - 0.004 16.7 0.1 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain KorB PF08535.5 CDO70084.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 KorB domain HTH_26 PF13443.1 CDO70084.1 - 0.032 14.4 0.0 0.041 14.0 0.0 1.1 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Sigma70_r4_2 PF08281.7 CDO70084.1 - 0.077 12.4 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 Ribosomal_S11 PF00411.14 CDO70085.1 - 5.3e-41 139.2 0.5 6.6e-41 138.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Acyltransferase PF01553.16 CDO70086.1 - 0.00021 20.7 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Spc42p PF11544.3 CDO70088.1 - 0.21 11.5 0.3 0.88 9.5 0.0 2.0 2 0 0 2 2 2 0 Spindle pole body component Spc42p DivIC PF04977.10 CDO70088.1 - 0.53 9.8 2.4 4 6.9 0.4 2.4 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 CDO70088.1 - 1.4 9.3 6.1 0.19 12.1 0.4 2.4 2 1 1 3 3 3 0 SlyX Synaptobrevin PF00957.16 CDO70089.1 - 2.8e-27 94.1 0.4 4e-27 93.6 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CDO70089.1 - 1.6e-21 75.6 0.0 2.4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain IstB_IS21_ATP PF08483.6 CDO70089.1 - 0.043 13.4 0.1 0.4 10.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal ClpB_D2-small PF10431.4 CDO70089.1 - 0.12 12.2 0.3 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein GAS PF13851.1 CDO70090.1 - 0.0015 17.7 9.6 0.003 16.7 6.7 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF106 PF01956.11 CDO70090.1 - 0.33 10.4 2.6 0.89 9.0 0.1 2.6 2 1 1 3 3 3 0 Integral membrane protein DUF106 Prefoldin_3 PF13758.1 CDO70090.1 - 0.63 9.8 5.7 1 9.1 0.3 2.5 2 0 0 2 2 2 0 Prefoldin subunit ERM PF00769.14 CDO70090.1 - 1.4 8.4 16.2 0.15 11.5 7.3 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family APG6 PF04111.7 CDO70090.1 - 3.6 6.5 11.3 5.8 5.8 7.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CDO70090.1 - 5.8 6.4 16.9 3.5 7.1 10.3 1.6 2 0 0 2 2 2 0 IncA protein Mo25 PF08569.6 CDO70091.1 - 8.2e-121 403.1 3.4 1.7e-119 398.8 0.7 2.0 2 0 0 2 2 2 2 Mo25-like Glycos_transf_2 PF00535.21 CDO70093.1 - 4.6e-28 98.0 0.0 6.2e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CDO70093.1 - 2.2e-11 43.9 0.0 3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CDO70093.1 - 6.2e-06 25.5 0.0 7.7e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CDO70093.1 - 0.14 11.4 0.0 0.42 9.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 F-box-like PF12937.2 CDO70094.1 - 6.3e-05 22.6 0.0 0.00037 20.1 0.0 2.4 2 1 0 2 2 2 1 F-box-like Lactonase PF10282.4 CDO70095.1 - 1e-12 47.8 0.0 1.7e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Lactonase PF10282.4 CDO70096.1 - 8e-34 117.2 0.0 7.6e-22 77.8 0.0 2.0 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller DUF1586 PF07625.6 CDO70096.1 - 0.11 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) Ribosomal_L24e PF01246.15 CDO70097.1 - 3.1e-30 103.8 0.5 3.1e-30 103.8 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e Ribosomal_60s PF00428.14 CDO70097.1 - 0.016 15.5 5.4 0.025 14.9 3.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4407 PF14362.1 CDO70097.1 - 0.052 12.5 5.2 0.062 12.2 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF106 PF01956.11 CDO70097.1 - 0.17 11.4 2.4 0.3 10.5 1.7 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF680 PF05079.7 CDO70097.1 - 0.34 11.4 2.2 0.8 10.2 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF680) Birna_RdRp PF04197.7 CDO70097.1 - 0.72 7.8 6.3 0.82 7.6 4.3 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) COX16 PF14138.1 CDO70097.1 - 0.98 9.6 6.0 0.65 10.2 0.3 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 LEA_3 PF03242.8 CDO70097.1 - 2 8.7 6.3 2.5 8.3 3.8 1.6 1 1 1 2 2 2 0 Late embryogenesis abundant protein AUX_IAA PF02309.11 CDO70097.1 - 2.3 7.9 5.9 2.7 7.6 4.1 1.1 1 0 0 1 1 1 0 AUX/IAA family MAP65_ASE1 PF03999.7 CDO70098.1 - 1.2e-61 209.1 9.7 3.4e-57 194.4 2.5 2.9 2 2 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.7 CDO70098.1 - 0.94 9.2 5.1 1.9 8.2 0.6 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Acetyltransf_1 PF00583.19 CDO70099.1 - 5.1e-11 42.4 0.0 7.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDO70099.1 - 3.5e-10 39.8 0.0 5.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CDO70099.1 - 0.0027 17.5 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO70099.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.1 CDO70099.1 - 0.033 14.3 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 CDO70100.1 - 4.7e-28 98.2 0.3 6.2e-28 97.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO70100.1 - 1.4e-23 83.9 0.0 1.6e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO70100.1 - 3e-15 56.3 0.1 5.3e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO70100.1 - 0.00027 20.4 0.1 0.00056 19.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1652 PF07865.6 CDO70100.1 - 0.069 12.7 0.0 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) Ldh_1_N PF00056.18 CDO70100.1 - 0.12 12.1 0.1 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DUF1744 PF08490.7 CDO70101.1 - 1.8e-107 359.4 0.0 2.5e-107 358.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CDO70101.1 - 2.7e-68 230.2 0.0 4.7e-68 229.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CDO70101.1 - 1.2e-19 70.4 0.0 8.1e-19 67.7 0.0 2.2 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CDO70101.1 - 1.4e-07 31.2 0.2 4.7e-07 29.5 0.2 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CDO70101.1 - 0.0021 17.8 0.1 0.013 15.2 0.0 2.4 3 0 0 3 3 3 1 RNase_H superfamily TF_Zn_Ribbon PF08271.7 CDO70101.1 - 0.086 12.1 0.3 0.31 10.3 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding zf-UBR PF02207.15 CDO70102.1 - 5.5e-11 42.0 8.1 5.5e-11 42.0 5.6 3.4 3 1 1 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 CDO70102.1 - 3.1e-07 29.9 1.1 3.1e-07 29.9 0.7 3.9 4 0 0 4 4 4 1 PHD-finger Hydantoinase_B PF02538.9 CDO70103.1 - 4.2e-184 612.6 0.0 1e-183 611.4 0.0 1.5 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Tetraspannin PF00335.15 CDO70105.1 - 1.3e-10 40.9 3.8 1.8e-10 40.5 2.7 1.1 1 0 0 1 1 1 1 Tetraspanin family ABC2_membrane_3 PF12698.2 CDO70105.1 - 0.0068 15.4 6.8 0.0094 15.0 4.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein 7TM_GPCR_Srh PF10318.4 CDO70105.1 - 0.017 13.9 2.3 0.021 13.6 1.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF975 PF06161.6 CDO70105.1 - 0.018 14.7 2.6 0.031 13.9 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF975) DUF1129 PF06570.6 CDO70105.1 - 0.035 13.4 0.4 0.045 13.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4064 PF13273.1 CDO70105.1 - 0.053 13.6 6.2 0.26 11.4 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Cellulose_synt PF03552.9 CDO70105.1 - 0.06 11.6 0.7 0.075 11.3 0.5 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF3169 PF11368.3 CDO70105.1 - 0.068 12.3 2.2 0.18 10.9 1.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) ABC2_membrane_2 PF12679.2 CDO70105.1 - 0.1 11.4 2.9 0.12 11.1 2.0 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Claudin_2 PF13903.1 CDO70105.1 - 0.11 12.2 9.7 0.37 10.4 6.5 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1673 PF07895.6 CDO70105.1 - 0.17 11.3 4.3 0.27 10.7 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF2721 PF11026.3 CDO70105.1 - 0.73 9.4 7.0 1.9 8.1 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) DUF1625 PF07787.7 CDO70105.1 - 1.5 7.9 9.8 1.4 8.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) Glyco_hydro_12 PF01670.11 CDO70106.1 - 4e-29 101.4 1.0 6.6e-29 100.6 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Hydrophobin PF01185.13 CDO70107.1 - 4e-21 75.2 11.4 4.8e-21 74.9 7.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 CDO70108.1 - 1.2e-20 73.6 7.2 1.6e-20 73.3 5.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 CDO70109.1 - 3.2e-23 81.9 10.1 3.9e-23 81.6 7.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 CDO70110.1 - 2.9e-20 72.4 12.3 3.5e-20 72.2 8.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF131 PF01998.12 CDO70110.1 - 0.25 10.7 0.2 0.25 10.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF131 Lamprin PF06403.6 CDO70110.1 - 0.41 10.3 4.4 1.8 8.3 3.1 1.9 1 1 0 1 1 1 0 Lamprin Toxin_12 PF07740.7 CDO70110.1 - 5.6 7.5 9.1 6.2 7.3 0.4 2.4 2 0 0 2 2 2 0 Ion channel inhibitory toxin Hydrophobin PF01185.13 CDO70111.1 - 1.2e-22 80.1 9.4 1.4e-22 79.9 6.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 CDO70112.1 - 1.6e-22 79.7 12.0 1.9e-22 79.4 8.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF4013 PF13197.1 CDO70112.1 - 0.12 11.7 2.4 0.17 11.2 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Hydrophobin PF01185.13 CDO70113.1 - 7.6e-17 61.5 2.2 9.8e-17 61.1 1.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF4448 PF14610.1 CDO70114.1 - 0.024 14.1 0.4 0.19 11.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) DUF605 PF04652.11 CDO70114.1 - 3.7 6.8 16.7 5.7 6.2 11.5 1.3 1 0 0 1 1 1 0 Vta1 like YtkA PF13115.1 CDO70117.1 - 0.079 13.3 0.0 0.83 10.0 0.0 2.4 2 0 0 2 2 2 0 YtkA-like RRM_6 PF14259.1 CDO70119.1 - 5.1e-07 29.5 0.0 2.5e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO70119.1 - 0.0053 16.3 0.0 0.025 14.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M28 PF04389.12 CDO70121.1 - 2.8e-16 59.7 0.0 7.3e-16 58.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 CDO70121.1 - 0.0013 18.2 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CDO70121.1 - 0.15 10.8 0.0 0.51 9.0 0.0 1.6 1 1 0 2 2 2 0 M42 glutamyl aminopeptidase OmpH PF03938.9 CDO70122.1 - 0.21 11.4 0.2 0.48 10.3 0.0 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Asp PF00026.18 CDO70123.1 - 4.8e-17 62.1 0.1 2.1e-16 60.0 0.1 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 CDO70123.1 - 0.0072 15.8 0.3 0.023 14.2 0.2 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal FAD_binding_3 PF01494.14 CDO70124.1 - 4.6e-16 58.8 0.5 4.9e-15 55.4 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain Suppressor_APC PF11414.3 CDO70126.1 - 0.19 11.5 1.3 0.49 10.2 0.9 1.7 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein SRF-TF PF00319.13 CDO70127.1 - 4.8e-12 44.9 0.0 9.1e-12 44.0 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 CDO70127.1 - 0.11 10.5 0.4 0.13 10.2 0.3 1.1 1 0 0 1 1 1 0 CDC45-like protein His_Phos_2 PF00328.17 CDO70128.1 - 1.7e-25 90.0 0.0 2.1e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) VPS28 PF03997.7 CDO70129.1 - 4.1e-63 212.4 0.0 4.7e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein DUF4451 PF14616.1 CDO70133.1 - 3.8e-08 33.1 12.9 0.0053 16.5 0.5 4.4 5 0 0 5 5 5 3 Domain of unknown function (DUF4451) Ecl1 PF12855.2 CDO70133.1 - 0.0012 18.0 8.0 0.13 11.5 0.2 3.5 3 0 0 3 3 3 2 Life-span regulatory factor Tmemb_55A PF09788.4 CDO70133.1 - 0.054 12.6 3.4 1.2 8.2 0.1 3.3 4 0 0 4 4 4 0 Transmembrane protein 55A Tnp_zf-ribbon_2 PF13842.1 CDO70133.1 - 0.16 12.4 2.4 65 4.0 0.0 4.2 4 0 0 4 4 4 0 DDE_Tnp_1-like zinc-ribbon PHD PF00628.24 CDO70133.1 - 0.38 10.4 7.0 15 5.3 0.3 4.2 4 0 0 4 4 4 0 PHD-finger zf-dskA_traR PF01258.12 CDO70133.1 - 6.4 6.6 11.7 4.9 6.9 0.3 4.3 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger Pkinase PF00069.20 CDO70134.1 - 1.3e-55 188.3 0.0 1.6e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70134.1 - 2.4e-18 66.1 0.0 3.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO70134.1 - 4.9e-10 39.5 0.0 8.2e-06 25.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CDO70134.1 - 7.6e-05 22.1 0.2 0.00017 21.0 0.1 1.5 1 1 0 1 1 1 1 RIO1 family DUF1679 PF07914.6 CDO70134.1 - 0.0028 16.3 0.1 0.96 8.0 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 CDO70134.1 - 0.0055 16.3 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase MA3 PF02847.12 CDO70134.1 - 0.049 13.3 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 MA3 domain Kdo PF06293.9 CDO70134.1 - 0.067 12.2 0.1 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.13 CDO70135.1 - 9.5e-05 21.3 0.2 0.039 12.8 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain PAT1 PF09770.4 CDO70135.1 - 7.8 4.5 16.1 2 6.5 9.0 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 CDO70136.1 - 3.1e-21 75.4 2.8 3.4e-21 75.3 0.0 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain DLIC PF05783.6 CDO70136.1 - 1.7 7.2 5.5 2.7 6.5 3.8 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) PqqD PF05402.7 CDO70137.1 - 0.062 13.3 0.1 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) SQS_PSY PF00494.14 CDO70138.1 - 1.1e-36 126.5 0.5 1.4e-36 126.1 0.3 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RCC1 PF00415.13 CDO70139.1 - 4e-43 145.3 11.6 1.5e-11 44.2 0.0 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDO70139.1 - 9.9e-25 85.5 17.8 1.7e-09 37.0 0.2 5.9 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat FAT PF02259.18 CDO70140.1 - 8.7e-118 393.3 5.1 8.7e-118 393.3 3.5 2.4 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 CDO70140.1 - 7.3e-55 185.9 0.4 1.8e-54 184.7 0.3 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 CDO70140.1 - 1.1e-47 161.9 4.9 5.9e-47 159.5 1.0 4.0 4 1 0 4 4 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 CDO70140.1 - 4.4e-38 129.3 0.1 4.4e-38 129.3 0.1 3.6 4 1 0 4 4 3 1 Rapamycin binding domain HEAT_2 PF13646.1 CDO70140.1 - 3.8e-18 65.5 19.1 0.00054 20.1 0.1 10.5 5 2 3 8 8 8 4 HEAT repeats FATC PF02260.15 CDO70140.1 - 2.6e-16 58.7 0.4 6.9e-16 57.3 0.3 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 CDO70140.1 - 1.9e-11 43.0 20.4 0.17 12.0 0.0 11.1 11 0 0 11 11 10 3 HEAT repeat Vac14_Fab1_bd PF12755.2 CDO70140.1 - 9.5e-06 25.9 3.2 9.5 6.6 0.0 8.2 8 2 2 10 10 9 0 Vacuolar 14 Fab1-binding region TPR_19 PF14559.1 CDO70140.1 - 0.0001 22.5 1.5 0.04 14.2 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat HEAT_EZ PF13513.1 CDO70140.1 - 0.00028 21.2 34.0 0.0036 17.7 0.2 12.2 12 2 3 15 15 14 2 HEAT-like repeat TPR_7 PF13176.1 CDO70140.1 - 0.00035 20.1 3.7 0.062 13.1 0.2 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat CLASP_N PF12348.3 CDO70140.1 - 0.00043 19.7 4.0 3.5 6.9 0.1 5.7 5 1 1 6 6 6 2 CLASP N terminal TPR_2 PF07719.12 CDO70140.1 - 0.0026 17.5 2.7 2.5 8.2 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDO70140.1 - 0.036 13.6 0.5 11 5.7 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CDO70140.1 - 0.13 13.0 4.7 1.2 9.9 0.0 4.7 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CDO70140.1 - 0.36 10.4 3.7 4 7.1 0.0 3.8 4 0 0 4 4 4 0 TPR repeat Cohesin_HEAT PF12765.2 CDO70140.1 - 0.53 10.2 10.3 0.42 10.6 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion TPR_16 PF13432.1 CDO70140.1 - 1.5 9.5 9.0 0.75 10.5 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat RCC1 PF00415.13 CDO70141.1 - 4.1e-16 58.9 1.0 0.00066 19.8 0.0 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDO70141.1 - 4.1e-07 29.4 14.7 0.00033 20.1 0.3 5.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 CDO70141.1 - 0.0091 15.6 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF4207 PF13904.1 CDO70142.1 - 0.076 12.3 10.2 0.15 11.4 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Aminoglyc_resit PF10706.4 CDO70143.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase Alpha_kinase PF02816.13 CDO70145.1 - 2.9e-05 23.8 0.0 0.00018 21.2 0.0 2.1 1 1 0 1 1 1 1 Alpha-kinase family PV-1 PF06637.6 CDO70146.1 - 0.16 10.5 7.9 0.25 9.8 5.5 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) APH PF01636.18 CDO70148.1 - 0.0067 16.1 0.2 4.2 7.0 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 CDO70148.1 - 0.014 14.6 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain HpcH_HpaI PF03328.9 CDO70149.1 - 1.2e-20 73.3 0.0 7.3e-20 70.8 0.0 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Inositol_P PF00459.20 CDO70151.1 - 2.3e-51 174.7 0.0 6.8e-51 173.1 0.0 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family MMR_HSR1 PF01926.18 CDO70153.1 - 6.8e-20 71.1 0.1 8.4e-15 54.7 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CDO70153.1 - 7.1e-08 31.8 0.0 4.1e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CDO70153.1 - 3.6e-05 23.2 0.0 0.0037 16.7 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CDO70153.1 - 0.00039 20.2 0.0 0.036 13.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 CDO70153.1 - 0.00048 19.3 0.0 0.00094 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CDO70153.1 - 0.0027 18.1 0.0 0.58 10.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 CDO70153.1 - 0.0049 16.8 0.5 0.59 10.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.11 CDO70153.1 - 0.012 14.7 0.0 0.046 12.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family ArgK PF03308.11 CDO70153.1 - 0.031 13.0 0.0 0.081 11.6 0.0 1.7 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 CDO70153.1 - 0.064 12.7 0.2 1.7 8.0 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 CDO70153.1 - 0.069 13.9 0.1 2.8 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CDO70153.1 - 0.089 12.2 0.0 6.8 6.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CDO70153.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B THF_DHG_CYH_C PF02882.14 CDO70153.1 - 0.15 11.1 0.3 0.29 10.1 0.0 1.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Septin PF00735.13 CDO70153.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_18 PF13238.1 CDO70153.1 - 1.1 9.6 0.0 1.1 9.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain Glyco_trans_2_3 PF13632.1 CDO70154.1 - 6.9e-55 185.7 0.4 6.9e-55 185.7 0.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CDO70154.1 - 7.5e-10 39.0 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CDO70154.1 - 0.0015 18.2 0.1 0.0049 16.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CDO70154.1 - 0.034 13.4 0.0 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 CDO70155.1 - 5.4e-22 77.9 0.4 9.1e-21 73.9 0.1 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 YniB PF14002.1 CDO70155.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 YniB-like protein Glyco_trans_2_3 PF13632.1 CDO70156.1 - 6.3e-55 185.8 0.6 6.3e-55 185.8 0.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CDO70156.1 - 2.4e-10 40.6 0.0 4.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CDO70156.1 - 0.0014 18.3 0.2 0.0048 16.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CDO70156.1 - 0.013 14.7 0.0 0.051 12.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 CDO70157.1 - 1.4e-20 73.4 0.2 4.2e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 VKOR PF07884.9 CDO70157.1 - 0.014 15.2 0.9 0.041 13.7 0.3 1.8 2 0 0 2 2 2 0 Vitamin K epoxide reductase family Glyco_hydro_16 PF00722.16 CDO70158.1 - 4.7e-19 68.4 0.5 4.8e-18 65.0 0.1 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 VKOR PF07884.9 CDO70158.1 - 0.042 13.6 0.2 0.042 13.6 0.2 1.6 2 0 0 2 2 2 0 Vitamin K epoxide reductase family Glyco_trans_2_3 PF13632.1 CDO70159.1 - 8.7e-49 165.8 1.3 8.7e-49 165.8 0.9 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CDO70159.1 - 2.1e-09 37.4 0.6 5.3e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CDO70159.1 - 0.014 15.0 0.1 0.095 12.3 0.0 2.3 3 0 0 3 3 3 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CDO70159.1 - 0.028 13.7 0.0 0.072 12.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF842 PF05811.8 CDO70159.1 - 0.11 11.9 0.5 0.23 10.9 0.3 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) FHA PF00498.21 CDO70160.1 - 0.00036 20.5 0.0 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 FHA domain ATP_bind_1 PF03029.12 CDO70161.1 - 9.9e-78 260.9 0.1 1.4e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CDO70161.1 - 3.8e-06 26.4 0.1 2.5e-05 23.8 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 CDO70161.1 - 7.5e-05 22.2 1.3 0.00016 21.1 0.1 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CDO70161.1 - 0.00031 19.5 0.0 0.064 12.0 0.0 2.2 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 CDO70161.1 - 0.00084 19.2 0.0 0.0025 17.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 CDO70161.1 - 0.001 18.9 0.0 0.0035 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDO70161.1 - 0.0014 17.7 0.1 0.029 13.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 CDO70161.1 - 0.0016 17.9 0.7 0.0081 15.6 0.5 1.9 1 1 0 1 1 1 1 AAA-like domain G-alpha PF00503.15 CDO70161.1 - 0.0046 15.6 3.4 0.043 12.5 0.0 2.5 3 0 0 3 3 3 1 G-protein alpha subunit AAA_17 PF13207.1 CDO70161.1 - 0.005 17.6 1.6 0.01 16.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 CDO70161.1 - 0.0065 15.7 0.1 0.035 13.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.7 CDO70161.1 - 0.0087 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 CDO70161.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CDO70161.1 - 0.025 13.4 0.0 0.15 10.8 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_PrkA PF08298.6 CDO70161.1 - 0.051 12.2 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain KAP_NTPase PF07693.9 CDO70161.1 - 0.056 12.4 0.0 0.07 12.1 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain SRP54 PF00448.17 CDO70161.1 - 0.072 12.5 0.0 0.65 9.4 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 CDO70161.1 - 0.075 12.8 0.1 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 CDO70161.1 - 0.099 12.0 0.1 0.88 8.9 0.1 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 CDO70161.1 - 0.11 12.5 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain Arf PF00025.16 CDO70161.1 - 0.13 11.5 0.0 1 8.5 0.0 2.3 3 0 0 3 3 3 0 ADP-ribosylation factor family DUF258 PF03193.11 CDO70161.1 - 0.15 11.2 0.1 0.61 9.2 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CDO70161.1 - 0.15 12.0 0.0 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 CDO70161.1 - 0.18 11.4 0.1 0.51 10.0 0.0 1.8 2 0 0 2 2 2 0 NTPase Pkinase PF00069.20 CDO70162.1 - 4.7e-72 242.2 0.0 5.6e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70162.1 - 2.7e-32 111.8 0.0 3.7e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO70162.1 - 5.7e-05 22.9 0.2 0.0052 16.5 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CDO70162.1 - 0.012 14.6 0.0 0.035 13.0 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.6 CDO70162.1 - 0.022 13.5 0.0 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 CDO70162.1 - 0.073 12.1 0.3 0.21 10.6 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WSC PF01822.14 CDO70163.1 - 2e-70 232.6 52.2 2.9e-20 71.9 7.0 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 CDO70163.1 - 1.3e-29 103.0 0.0 1.7e-27 96.0 0.0 3.0 2 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CDO70163.1 - 3e-16 59.2 1.4 1.4e-15 57.1 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.10 CDO70163.1 - 0.038 13.7 1.1 3.1 7.7 0.0 4.1 5 0 0 5 5 5 0 Kelch motif SAC3_GANP PF03399.11 CDO70164.1 - 1e-24 87.2 0.9 1.7e-24 86.4 0.6 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Fer4_17 PF13534.1 CDO70164.1 - 0.18 12.2 0.1 0.56 10.5 0.0 1.9 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF2347 PF09804.4 CDO70165.1 - 3.6e-46 157.6 0.0 5.7e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 CDO70165.1 - 7.4e-05 21.4 0.0 0.43 9.0 0.1 3.2 3 0 0 3 3 3 2 Transport protein Avl9 DUF4484 PF14831.1 CDO70165.1 - 0.0001 22.4 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 CDO70165.1 - 0.01 15.5 0.0 0.033 13.8 0.0 1.8 1 1 0 1 1 1 0 Stabilization of polarity axis DUF295 PF03478.13 CDO70165.1 - 0.069 12.5 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF295) SnAPC_2_like PF11035.3 CDO70165.1 - 0.097 12.1 1.1 1.7 8.0 0.4 2.1 2 0 0 2 2 2 0 Small nuclear RNA activating complex subunit 2-like Gti1_Pac2 PF09729.4 CDO70168.1 - 3.7e-56 189.6 0.0 9.4e-56 188.2 0.0 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family Transposase_21 PF02992.9 CDO70170.1 - 5.7e-15 55.0 0.0 1.1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Herpes_BLRF2 PF05812.7 CDO70172.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein HsbA PF12296.3 CDO70173.1 - 0.025 14.4 0.2 0.091 12.6 0.1 1.9 2 0 0 2 2 2 0 Hydrophobic surface binding protein A zf-RING_2 PF13639.1 CDO70174.1 - 1.9e-07 30.7 7.0 4.3e-07 29.6 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDO70174.1 - 4.9e-06 26.5 2.0 1.1e-05 25.3 1.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 CDO70174.1 - 1.3e-05 25.1 4.3 2.8e-05 23.9 3.0 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 CDO70174.1 - 0.00037 20.2 1.9 0.00093 18.9 1.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CDO70174.1 - 0.011 15.7 6.3 0.022 14.8 4.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.20 CDO70174.1 - 0.05 13.2 8.0 0.091 12.4 5.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CDO70174.1 - 0.4 10.3 5.5 0.75 9.4 3.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_1 PF00130.17 CDO70174.1 - 0.41 10.4 4.7 0.18 11.5 1.2 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 CDO70174.1 - 0.54 10.3 8.2 1.1 9.3 5.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO70174.1 - 2 8.1 6.3 4.8 6.9 4.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CDO70174.1 - 4.9 7.2 6.9 12 6.0 4.8 1.7 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 CDO70174.1 - 6.8 6.4 6.3 13 5.5 4.4 1.5 1 0 0 1 1 1 0 PHD-finger p450 PF00067.17 CDO70175.1 - 2e-74 250.8 0.0 4.5e-74 249.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 HSP20 PF00011.16 CDO70176.1 - 4.7e-10 39.2 0.0 1.7e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Hsp20/alpha crystallin family PAT1 PF09770.4 CDO70176.1 - 0.74 7.9 43.9 0.94 7.6 30.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SMN PF06003.7 CDO70176.1 - 0.82 8.7 5.3 1.3 8.1 3.7 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Peptidase_S46 PF10459.4 CDO70176.1 - 3.2 6.0 6.5 4.1 5.6 4.5 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF2046 PF09755.4 CDO70177.1 - 1.2e-12 47.3 7.8 1.2e-12 47.3 5.4 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DUF972 PF06156.8 CDO70177.1 - 1.8 8.9 5.5 21 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) ChAPs PF09295.5 CDO70179.1 - 5.7e-150 499.4 0.0 5.2e-149 496.3 0.0 1.9 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 CDO70179.1 - 6.5e-09 36.0 1.5 1.4e-05 25.3 0.1 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CDO70179.1 - 2.4e-06 27.0 4.5 0.0063 16.1 0.0 4.2 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 CDO70179.1 - 2.9e-06 26.7 7.1 2.3 8.3 0.1 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 CDO70179.1 - 3.4e-06 27.1 1.7 4.5 8.1 0.0 6.4 3 2 4 7 7 7 1 Tetratricopeptide repeat Apc3 PF12895.2 CDO70179.1 - 1.7e-05 24.8 4.8 0.13 12.4 0.1 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CDO70179.1 - 4.7e-05 23.9 0.1 0.013 16.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO70179.1 - 0.00011 21.6 1.0 0.26 11.1 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDO70179.1 - 0.00096 19.4 0.4 4.3 8.0 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDO70179.1 - 0.035 14.0 5.4 6.5 6.7 0.0 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.3 CDO70179.1 - 1.4 7.5 11.4 0.25 10.0 0.0 3.0 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 AA_kinase PF00696.23 CDO70180.1 - 2.6e-34 118.8 0.0 3.8e-33 115.0 0.0 2.2 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 CDO70180.1 - 2.5e-13 49.1 0.8 7.6e-06 25.2 0.0 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 CDO70180.1 - 5.6e-08 32.1 0.8 3.5e-05 23.2 0.1 2.6 2 0 0 2 2 2 2 ACT domain Rrf2 PF02082.15 CDO70180.1 - 0.11 12.6 0.1 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator Pox_F16 PF04708.7 CDO70180.1 - 0.14 11.3 0.2 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein G-alpha PF00503.15 CDO70181.1 - 3e-116 388.3 0.0 6.6e-79 265.3 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit AAA_29 PF13555.1 CDO70181.1 - 0.0016 17.9 0.0 0.0039 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arf PF00025.16 CDO70181.1 - 0.013 14.7 0.1 0.46 9.7 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DAP3 PF10236.4 CDO70181.1 - 0.036 13.0 0.1 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 CDO70181.1 - 0.053 13.6 0.1 0.43 10.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 CDO70181.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter HMG-CoA_red PF00368.13 CDO70182.1 - 1.8e-155 517.2 8.2 1.9e-154 513.8 5.7 2.1 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 CDO70182.1 - 4.7e-19 68.3 0.6 1e-18 67.2 0.4 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CDO70182.1 - 2e-06 26.0 0.4 2.9e-06 25.5 0.3 1.1 1 0 0 1 1 1 1 Patched family HPIH PF13323.1 CDO70182.1 - 0.11 12.1 0.5 0.37 10.4 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain with HPIH motif 2-Hacid_dh_C PF02826.14 CDO70184.1 - 1.2e-42 145.0 0.0 1.8e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CDO70184.1 - 7.6e-12 44.8 0.0 3.1e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CDO70184.1 - 2.7e-05 24.0 0.1 7.1e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CDO70184.1 - 0.00045 20.6 0.0 0.00086 19.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 CDO70184.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ion_trans_2 PF07885.11 CDO70185.1 - 2.2e-26 91.3 32.0 1.3e-14 53.6 4.9 3.1 3 0 0 3 3 3 2 Ion channel TOM13 PF08219.6 CDO70185.1 - 0.042 13.6 0.2 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 Outer membrane protein TOM13 Sec3_C PF09763.4 CDO70185.1 - 0.46 8.5 3.9 0.65 8.0 2.7 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Transposase_21 PF02992.9 CDO70186.1 - 2.5e-16 59.4 0.0 4.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Herpes_BLRF2 PF05812.7 CDO70188.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein PSD4 PF07631.6 CDO70192.1 - 0.0082 16.5 0.1 0.018 15.3 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1592) Aldo_ket_red PF00248.16 CDO70195.1 - 9e-52 175.6 0.0 1.1e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 CDO70196.1 - 1.6e-50 171.5 0.0 2.3e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 CDO70196.1 - 4.5e-28 96.0 0.3 2.3e-07 30.4 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 CDO70196.1 - 0.0025 17.3 0.1 0.0084 15.5 0.1 1.9 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 CDO70196.1 - 0.08 11.0 1.2 2.9 5.9 0.1 2.8 2 2 2 4 4 4 0 Nucleoporin Nup120/160 HAD_2 PF13419.1 CDO70197.1 - 1.3e-25 90.6 0.1 1.7e-25 90.2 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDO70197.1 - 2.1e-07 31.5 0.0 5.5e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CDO70197.1 - 3.1e-06 26.8 0.0 5.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4102 PF13356.1 CDO70200.1 - 0.048 13.5 0.0 0.19 11.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) MFS_1 PF07690.11 CDO70201.1 - 1e-09 37.6 45.0 1.2e-07 30.8 16.0 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Ribosomal_L7Ae PF01248.21 CDO70202.1 - 1.7e-22 78.7 0.8 2.9e-22 77.9 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Adenine_glyco PF03352.8 CDO70202.1 - 0.039 13.4 0.4 0.074 12.5 0.2 1.4 1 0 0 1 1 1 0 Methyladenine glycosylase Phage_GP20 PF06810.6 CDO70205.1 - 0.016 14.6 0.5 0.022 14.1 0.3 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Ino80_Iec3 PF14612.1 CDO70205.1 - 0.019 15.0 0.9 0.03 14.3 0.7 1.2 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Occludin_ELL PF07303.8 CDO70205.1 - 0.032 14.9 0.3 0.05 14.3 0.2 1.2 1 0 0 1 1 1 0 Occludin homology domain ADIP PF11559.3 CDO70205.1 - 0.063 13.1 0.5 0.093 12.6 0.4 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 CDO70205.1 - 0.09 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 IncA protein Sigma70_ner PF04546.8 CDO70205.1 - 0.11 12.0 0.5 0.16 11.5 0.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DASH_Spc34 PF08657.5 CDO70205.1 - 0.12 12.0 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 PAT1 PF09770.4 CDO70205.1 - 1.8 6.7 17.5 2.1 6.4 12.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PBP PF01161.15 CDO70206.1 - 5e-22 78.3 0.2 6.2e-22 78.0 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein APH PF01636.18 CDO70207.1 - 0.00031 20.5 0.6 0.00031 20.5 0.4 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Toxin_49 PF15529.1 CDO70207.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 49 SAPS PF04499.10 CDO70210.1 - 0.0097 14.5 3.2 0.022 13.3 2.2 1.5 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein LysM PF01476.15 CDO70211.1 - 8.5e-14 51.1 0.4 2.2e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 LysM domain Dimer_Tnp_hAT PF05699.9 CDO70213.1 - 2.1e-13 49.6 0.0 4.9e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nop14 PF04147.7 CDO70213.1 - 1.9 6.3 4.1 1 7.1 1.2 1.7 2 0 0 2 2 2 0 Nop14-like family ABC_membrane_2 PF06472.10 CDO70214.1 - 7.8e-86 287.6 1.5 1.4e-85 286.8 0.9 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CDO70214.1 - 4.3e-17 62.6 0.0 1e-16 61.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CDO70214.1 - 0.00023 21.2 0.1 0.00072 19.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CDO70214.1 - 0.011 16.1 0.1 0.026 14.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CDO70214.1 - 0.023 14.6 0.0 0.081 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CDO70214.1 - 0.04 13.4 0.0 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 CDO70214.1 - 0.054 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF4258 PF14076.1 CDO70214.1 - 0.056 13.4 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) DUF258 PF03193.11 CDO70214.1 - 0.098 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 CDO70214.1 - 0.15 12.8 0.0 0.97 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 CDO70214.1 - 0.18 10.4 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PRELI PF04707.9 CDO70215.1 - 1.8e-33 115.3 0.0 2.1e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family B-block_TFIIIC PF04182.7 CDO70216.1 - 5.8e-11 42.0 0.1 1.5e-07 31.1 0.0 3.7 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC HTH_24 PF13412.1 CDO70216.1 - 2.5e-05 23.5 2.8 0.13 11.6 0.0 5.5 5 0 0 5 5 5 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.2 CDO70216.1 - 0.0003 20.5 0.5 24 4.8 0.0 5.7 6 0 0 6 6 6 0 Helix-turn-helix domain RPA_C PF08784.6 CDO70216.1 - 0.00071 19.9 0.0 3.5 8.0 0.0 4.7 4 0 0 4 4 4 1 Replication protein A C terminal MarR_2 PF12802.2 CDO70216.1 - 0.003 17.2 0.3 1.2 8.8 0.0 4.5 4 0 0 4 4 4 1 MarR family HTH_27 PF13463.1 CDO70216.1 - 0.012 15.9 0.0 0.34 11.2 0.0 3.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain MarR PF01047.17 CDO70216.1 - 0.045 13.4 0.0 0.45 10.2 0.0 2.7 2 0 0 2 2 2 0 MarR family Nucleoplasmin PF03066.10 CDO70217.1 - 0.001 18.5 5.0 0.0021 17.6 3.5 1.4 1 0 0 1 1 1 1 Nucleoplasmin TFIIA PF03153.8 CDO70217.1 - 0.018 14.9 4.7 0.031 14.1 3.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.1 CDO70217.1 - 0.035 13.7 5.6 35 4.0 6.4 2.4 2 1 0 2 2 2 0 FAM176 family Retinal PF15449.1 CDO70217.1 - 0.04 11.6 8.4 0.061 10.9 5.8 1.3 1 0 0 1 1 1 0 Retinal protein ANAPC15 PF15243.1 CDO70217.1 - 0.079 13.0 9.9 0.16 12.0 6.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Senescence_reg PF04520.8 CDO70217.1 - 0.083 13.3 7.3 0.16 12.4 5.1 1.5 1 0 0 1 1 1 0 Senescence regulator Cwf_Cwc_15 PF04889.7 CDO70217.1 - 0.088 12.5 5.6 0.14 11.8 3.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 CDO70217.1 - 0.1 12.2 7.3 0.17 11.5 5.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 CDO70217.1 - 0.17 11.1 4.2 0.25 10.5 2.9 1.2 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 CDO70217.1 - 0.2 10.7 8.8 0.33 10.0 6.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.6 CDO70217.1 - 0.2 11.4 4.7 0.37 10.5 3.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PPP4R2 PF09184.6 CDO70217.1 - 0.31 10.5 8.9 0.46 9.9 6.2 1.1 1 0 0 1 1 1 0 PPP4R2 PRELI PF04707.9 CDO70218.1 - 8.4e-34 116.4 0.0 1e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Lactamase_B PF00753.22 CDO70220.1 - 1.5e-06 28.0 0.0 3.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CDO70220.1 - 0.00018 21.1 0.1 0.0014 18.2 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CDO70220.1 - 0.049 13.3 0.0 0.75 9.4 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase superfamily domain TGS PF02824.16 CDO70221.1 - 0.00018 21.2 0.2 0.013 15.2 0.1 2.4 1 1 1 2 2 2 2 TGS domain Pkinase PF00069.20 CDO70222.1 - 3.3e-61 206.7 0.0 7.7e-61 205.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70222.1 - 6.3e-34 117.2 0.0 1.1e-24 86.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CDO70222.1 - 1.7e-05 23.9 0.1 0.00075 18.5 0.1 2.3 1 1 0 1 1 1 1 Kinase-like MCM PF00493.18 CDO70223.1 - 3.1e-127 423.9 0.0 4.4e-127 423.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CDO70223.1 - 4.3e-24 85.3 0.2 1.4e-23 83.6 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CDO70223.1 - 7.1e-08 31.8 0.0 1e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CDO70223.1 - 0.0025 17.4 0.0 0.009 15.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CDO70223.1 - 0.0051 16.2 0.1 0.023 14.1 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain WD40 PF00400.27 CDO70225.1 - 1.4e-40 135.7 10.1 3.1e-09 36.3 0.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 CDO70225.1 - 0.002 17.6 0.0 0.02 14.3 0.0 2.3 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 CDO70225.1 - 0.08 11.0 0.3 3.3 5.7 0.1 2.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Mito_carr PF00153.22 CDO70226.1 - 1.1e-15 57.0 0.0 1.5e-06 27.7 0.0 2.9 2 1 0 2 2 2 2 Mitochondrial carrier protein RINT1_TIP1 PF04437.8 CDO70227.1 - 7e-70 235.9 0.0 1.9e-69 234.5 0.0 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family DUF745 PF05335.8 CDO70227.1 - 0.24 10.9 6.8 1 8.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) NT5C PF06941.7 CDO70228.1 - 5.4e-08 32.5 2.8 1.2e-06 28.2 0.0 3.3 2 1 1 3 3 3 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 CDO70228.1 - 0.00014 22.1 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDO70228.1 - 0.00055 20.4 0.0 0.001 19.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 CDO70228.1 - 0.0032 16.8 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.1 CDO70228.1 - 0.006 16.4 0.0 0.012 15.4 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDO70228.1 - 0.03 13.9 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase LNS2 PF08235.8 CDO70228.1 - 0.086 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) HAD PF12710.2 CDO70228.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase p450 PF00067.17 CDO70229.1 - 1.8e-56 191.5 0.0 3.5e-40 137.8 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 GTP_cyclohydroI PF01227.17 CDO70229.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I Pro_CA PF00484.14 CDO70230.1 - 4.9e-28 98.0 0.2 8.6e-28 97.2 0.0 1.4 2 0 0 2 2 2 1 Carbonic anhydrase ThiI PF02568.9 CDO70230.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) RIC1 PF07064.8 CDO70231.1 - 1.7e-76 257.0 0.1 2.7e-76 256.4 0.0 1.3 1 0 0 1 1 1 1 RIC1 AftA_N PF12250.3 CDO70231.1 - 0.031 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal PD40 PF07676.7 CDO70231.1 - 0.041 13.5 0.1 2.2 8.0 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 CDO70231.1 - 0.08 12.8 1.3 14 5.7 0.1 3.8 5 0 0 5 5 5 0 WD domain, G-beta repeat DIOX_N PF14226.1 CDO70232.1 - 0.00026 21.4 1.0 0.0036 17.8 0.0 2.6 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO70232.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Glyco_transf_28 PF03033.15 CDO70233.1 - 2.8e-25 88.7 0.0 6.6e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CDO70233.1 - 8.4e-20 70.0 0.6 6.2e-13 48.0 0.0 3.1 3 0 0 3 3 3 2 GRAM domain PH PF00169.24 CDO70233.1 - 8.4e-14 51.6 0.2 6.9e-12 45.5 0.1 3.3 3 0 0 3 3 3 1 PH domain UDPGT PF00201.13 CDO70233.1 - 1.9e-06 26.7 0.0 3.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.1 CDO70233.1 - 1.6e-05 25.1 2.2 0.0012 19.0 0.9 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 CDO70233.1 - 0.011 15.7 0.1 0.026 14.6 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.1 CDO70233.1 - 0.051 13.6 0.0 0.19 11.7 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain Glyco_tran_28_C PF04101.11 CDO70233.1 - 0.093 12.3 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain SUR7 PF06687.7 CDO70234.1 - 5.9e-15 55.4 5.9 7.8e-15 55.0 4.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CDO70234.1 - 0.053 13.2 8.6 0.08 12.6 5.9 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PIRT PF15099.1 CDO70234.1 - 0.25 10.5 1.8 0.41 9.8 1.2 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Glyco_hydro_72 PF03198.9 CDO70235.1 - 5e-88 295.1 0.0 7.4e-88 294.5 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CDO70235.1 - 6.6e-20 71.3 0.6 1.8e-19 70.0 0.4 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 CDO70235.1 - 0.0085 15.3 0.1 0.017 14.2 0.1 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Polysacc_deac_1 PF01522.16 CDO70236.1 - 6.2e-31 106.6 0.0 1.2e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CDO70236.1 - 0.0031 16.4 0.0 0.0044 15.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 NAP PF00956.13 CDO70237.1 - 3.1e-35 121.4 7.0 1.1e-34 119.6 4.8 1.8 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) GOLD_2 PF13897.1 CDO70237.1 - 0.055 13.7 1.9 0.48 10.6 0.3 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking YL1 PF05764.8 CDO70237.1 - 0.06 12.9 5.1 0.094 12.3 3.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein DicB PF05358.6 CDO70237.1 - 0.073 12.5 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 DicB protein DUF4611 PF15387.1 CDO70237.1 - 0.71 10.0 8.3 0.31 11.2 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Myc_N PF01056.13 CDO70237.1 - 1 8.4 4.9 1.8 7.6 3.4 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Syja_N PF02383.13 CDO70238.1 - 3.2e-90 302.1 0.2 5.2e-90 301.4 0.0 1.4 2 0 0 2 2 2 1 SacI homology domain LRR_9 PF14580.1 CDO70239.1 - 1.9e-58 196.8 0.2 2.6e-58 196.4 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CDO70239.1 - 9.8e-12 44.2 11.3 1e-05 25.0 2.2 3.0 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO70239.1 - 1.7e-08 34.1 6.9 2e-08 33.8 3.2 2.3 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 CDO70239.1 - 0.0026 17.5 11.1 3.2 8.1 0.3 5.2 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CDO70239.1 - 0.0034 17.3 7.1 3.9 8.0 0.5 4.7 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 CDO70239.1 - 0.81 9.9 9.7 7.5 6.9 1.3 4.3 4 1 1 5 5 5 0 Leucine Rich repeat DUF4149 PF13664.1 CDO70240.1 - 1.9e-19 69.5 2.7 1.9e-19 69.5 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) PY_rept_46 PF09689.5 CDO70240.1 - 0.15 12.4 0.3 0.25 11.6 0.2 1.3 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) MitMem_reg PF13012.1 CDO70241.1 - 1.8e-19 69.9 0.1 2.5e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CDO70241.1 - 6.9e-11 41.8 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HAUS4 PF14735.1 CDO70241.1 - 0.0061 15.8 0.2 0.0091 15.3 0.2 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 MCM PF00493.18 CDO70242.1 - 2.3e-141 470.4 0.2 2.9e-141 470.0 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CDO70242.1 - 1.8e-18 67.1 0.3 6.3e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CDO70242.1 - 7.5e-07 28.5 0.0 0.00024 20.3 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CDO70242.1 - 9.2e-05 22.1 0.0 0.00023 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CDO70242.1 - 0.00044 19.8 0.1 0.0029 17.2 0.0 2.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 CDO70242.1 - 0.0017 18.6 0.5 0.0086 16.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 CDO70242.1 - 0.05 13.8 0.0 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CDO70242.1 - 0.11 12.0 0.0 5.6 6.4 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF3128 PF11326.3 CDO70243.1 - 8.7e-18 64.2 0.2 1.1e-17 63.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Jiv90 PF14901.1 CDO70243.1 - 0.13 12.2 0.5 0.17 11.9 0.3 1.4 1 1 0 1 1 1 0 Cleavage inducing molecular chaperone Catalase PF00199.14 CDO70245.1 - 5.2e-143 476.3 0.1 1.3e-141 471.8 0.0 2.1 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CDO70245.1 - 4.2e-18 64.9 0.1 8.7e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 CDO70245.1 - 2.1e-10 40.2 0.0 3.8e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CDO70245.1 - 4.7e-05 22.7 0.0 8.1e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase zf-C2H2 PF00096.21 CDO70246.1 - 2.5e-06 27.4 0.3 2.5e-06 27.4 0.2 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO70246.1 - 3.2e-06 27.1 7.0 0.02 15.1 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CDO70246.1 - 0.001 19.2 0.7 0.001 19.2 0.5 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CDO70246.1 - 0.14 12.3 1.8 0.35 11.0 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3889 PF13028.1 CDO70246.1 - 0.19 11.3 0.4 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) Peptidase_S10 PF00450.17 CDO70247.1 - 5.4e-90 302.5 3.2 6.6e-90 302.2 2.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Nramp PF01566.13 CDO70248.1 - 2.4e-75 253.5 22.3 2.4e-75 253.5 15.5 2.1 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Med6 PF04934.9 CDO70249.1 - 8.8e-37 125.7 0.0 1.3e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Clat_adaptor_s PF01217.15 CDO70250.1 - 2.2e-40 137.6 0.2 9e-40 135.6 0.2 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain EHN PF06441.7 CDO70251.1 - 4.3e-28 97.4 0.5 9e-28 96.4 0.0 1.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 CDO70251.1 - 1.6e-05 24.5 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDO70251.1 - 4e-05 23.6 0.5 9.4e-05 22.3 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO70251.1 - 0.041 13.7 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase CBM_5_12 PF02839.9 CDO70253.1 - 3.3e-10 39.3 25.9 0.00013 21.5 3.6 3.6 3 0 0 3 3 3 3 Carbohydrate binding domain CBM_5_12_2 PF14600.1 CDO70253.1 - 0.00083 18.9 12.3 0.017 14.7 1.4 2.6 2 0 0 2 2 2 2 Cellulose-binding domain Glyco_hydro_18 PF00704.23 CDO70254.1 - 6.4e-05 22.5 0.3 7.9e-05 22.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_49 PF03718.8 CDO70254.1 - 0.025 12.6 0.1 0.03 12.3 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 Pkinase PF00069.20 CDO70255.1 - 1.5e-56 191.4 0.0 1.7e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70255.1 - 1.1e-19 70.5 0.0 1.6e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO70255.1 - 7.2e-06 25.9 0.6 0.0002 21.1 0.1 2.6 2 1 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO70255.1 - 0.015 14.8 0.1 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 CDO70255.1 - 0.05 12.9 1.0 1.6 8.0 0.0 2.6 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Kdo PF06293.9 CDO70255.1 - 0.061 12.3 0.1 0.11 11.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CTDII PF01556.13 CDO70256.1 - 9.1e-33 112.0 0.3 7.5e-24 83.4 0.0 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CDO70256.1 - 1.4e-24 85.6 3.4 2e-24 85.0 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CDO70256.1 - 6.3e-12 45.3 15.0 6.3e-12 45.3 10.4 2.0 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 CDO70256.1 - 9.6 5.9 9.0 6.3 6.5 0.9 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family MFS_1 PF07690.11 CDO70257.1 - 4.3e-39 134.2 45.9 2.2e-37 128.5 31.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO70257.1 - 1.1e-09 37.4 10.6 1.1e-09 37.4 7.3 3.1 2 1 2 4 4 4 1 Sugar (and other) transporter DUF872 PF05915.7 CDO70257.1 - 0.14 12.0 4.2 0.16 11.8 0.8 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) MFS_1_like PF12832.2 CDO70257.1 - 0.61 9.9 6.7 14 5.5 0.3 3.7 3 0 0 3 3 3 0 MFS_1 like family Choline_kinase PF01633.15 CDO70258.1 - 2.6e-51 174.2 0.0 3.5e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CDO70258.1 - 1e-15 58.1 2.5 1e-15 58.1 1.7 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CDO70258.1 - 0.19 10.8 0.0 0.51 9.4 0.0 1.7 1 1 0 1 1 1 0 Ecdysteroid kinase zf-CCCH PF00642.19 CDO70259.1 - 2.9e-11 42.7 2.4 2.9e-11 42.7 1.7 3.1 2 1 1 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CDO70259.1 - 0.065 13.2 0.4 0.065 13.2 0.3 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF3437 PF11919.3 CDO70260.1 - 3.1e-25 87.7 0.0 1.4e-24 85.5 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 CDO70260.1 - 1.8e-05 24.4 6.2 0.0072 16.3 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 CDO70260.1 - 0.00037 20.7 0.1 0.1 12.8 0.0 3.9 3 1 1 4 4 4 1 HEAT repeats Cnd1 PF12717.2 CDO70260.1 - 0.0011 18.8 0.2 0.39 10.5 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF1546 PF07571.8 CDO70260.1 - 0.028 14.5 0.1 0.2 11.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Chalcone PF02431.10 CDO70261.1 - 9.5e-27 93.6 0.0 3.7e-26 91.7 0.0 1.8 1 1 0 1 1 1 1 Chalcone-flavanone isomerase TIM21 PF08294.6 CDO70262.1 - 4.5e-22 78.2 0.0 2.9e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 TIM21 ATP-synt_F PF01990.12 CDO70263.1 - 4.1e-31 107.2 0.1 4.7e-31 107.0 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 CDO70263.1 - 0.012 14.5 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase AhpC-TSA PF00578.16 CDO70263.1 - 0.051 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family DUF2666 PF10869.3 CDO70263.1 - 0.083 12.9 0.0 0.095 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) SGT1 PF07093.6 CDO70264.1 - 8.3e-135 450.4 16.3 1.4e-133 446.3 11.3 2.0 1 1 0 1 1 1 1 SGT1 protein zf-C3HC4_2 PF13923.1 CDO70266.1 - 7.8e-09 35.4 10.7 1.2e-08 34.8 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO70266.1 - 2.1e-08 33.6 8.8 3.2e-08 33.0 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO70266.1 - 2.2e-08 33.6 7.0 3.2e-08 33.0 4.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO70266.1 - 2.1e-07 30.6 10.5 3.3e-07 30.0 7.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CDO70266.1 - 1.6e-05 24.5 9.7 0.00011 21.8 7.3 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CDO70266.1 - 3.6e-05 23.5 10.8 6.4e-05 22.7 7.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CDO70266.1 - 0.0053 16.4 2.8 0.023 14.3 1.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CDO70266.1 - 0.035 13.9 1.8 0.064 13.0 1.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pellino PF04710.9 CDO70266.1 - 0.065 11.8 0.2 0.087 11.4 0.2 1.2 1 0 0 1 1 1 0 Pellino Rad50_zn_hook PF04423.9 CDO70266.1 - 0.09 12.2 0.4 5.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_6 PF14835.1 CDO70266.1 - 0.12 12.1 5.7 0.21 11.4 3.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein GAGA PF09237.6 CDO70266.1 - 0.15 11.6 6.6 1.1 8.8 0.4 2.7 3 0 0 3 3 3 0 GAGA factor zf-MIZ PF02891.15 CDO70266.1 - 0.18 11.3 6.1 0.31 10.6 4.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 CDO70266.1 - 0.29 10.7 7.9 1.3 8.6 5.8 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CDO70266.1 - 0.3 10.6 3.7 0.53 9.8 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Translin PF01997.11 CDO70268.1 - 1e-55 188.4 0.0 1.2e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Translin family DcpS_C PF11969.3 CDO70269.1 - 3.7e-05 23.9 0.2 8.2e-05 22.8 0.2 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3437 PF11919.3 CDO70270.1 - 3.2e-31 106.8 0.1 1.2e-30 105.0 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 CDO70270.1 - 8.7e-07 28.5 1.2 0.0075 16.2 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 CDO70270.1 - 0.0015 18.8 2.9 0.37 11.1 0.0 4.5 6 0 0 6 6 6 1 HEAT repeats HD_assoc PF13286.1 CDO70270.1 - 0.0026 17.9 0.0 0.068 13.4 0.0 2.6 2 0 0 2 2 2 1 Phosphohydrolase-associated domain Arm PF00514.18 CDO70270.1 - 0.11 12.4 0.2 1.1 9.1 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF2524 PF10732.4 CDO70271.1 - 0.028 14.5 0.0 0.087 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Ycf1 PF05758.7 CDO70272.1 - 0.86 7.2 1.5 1.3 6.6 1.1 1.1 1 0 0 1 1 1 0 Ycf1 DUF607 PF04678.8 CDO70272.1 - 3.9 7.3 4.1 7.1 6.5 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 GBP_C PF02841.9 CDO70272.1 - 6.9 5.7 14.1 12 4.9 9.8 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain HAUS6_N PF14661.1 CDO70272.1 - 7.2 5.8 9.7 13 5.0 6.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ATP-grasp_2 PF08442.5 CDO70273.1 - 2.2e-71 239.4 0.0 4e-71 238.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CDO70273.1 - 2.7e-26 91.9 0.0 4.7e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 CDO70273.1 - 8.6e-14 51.2 0.0 5e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 CDO70273.1 - 3.3e-06 26.8 0.1 0.0024 17.4 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 CDO70273.1 - 0.0016 18.1 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 CDO70273.1 - 0.14 11.5 0.1 0.4 10.0 0.0 1.8 2 1 0 2 2 2 0 ATP-grasp domain Hist_deacetyl PF00850.14 CDO70274.1 - 6.2e-80 268.7 0.0 1e-79 268.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain XPA_C PF05181.7 CDO70275.1 - 0.0057 16.2 0.4 0.012 15.1 0.3 1.5 1 0 0 1 1 1 1 XPA protein C-terminus DUF4585 PF15232.1 CDO70275.1 - 0.014 15.2 0.3 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4585) XPA_N PF01286.13 CDO70275.1 - 0.019 14.6 7.7 0.02 14.5 2.1 2.5 2 0 0 2 2 2 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 CDO70275.1 - 6.6 6.7 9.0 16 5.5 0.1 2.8 2 1 0 2 2 2 0 Zinc ribbon domain 4HBT_3 PF13622.1 CDO70276.1 - 1.1e-08 35.0 1.4 2.8e-05 24.0 0.1 2.1 1 1 1 2 2 2 2 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 CDO70276.1 - 9.2e-06 25.3 0.0 0.016 14.8 0.0 2.5 2 1 0 2 2 2 2 Acyl-CoA thioesterase Ribosomal_S27e PF01667.12 CDO70277.1 - 1.6e-29 101.2 1.5 1.9e-29 100.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CDO70277.1 - 0.00053 19.8 0.5 0.0007 19.4 0.3 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 CDO70277.1 - 0.017 14.4 1.3 0.026 13.8 0.9 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding DUF678 PF05077.7 CDO70277.1 - 0.022 14.7 3.5 0.23 11.4 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF678) DUF2752 PF10825.3 CDO70277.1 - 0.1 12.6 2.4 0.61 10.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2752) FYVE PF01363.16 CDO70277.1 - 0.12 12.2 0.9 0.17 11.8 0.6 1.3 1 0 0 1 1 1 0 FYVE zinc finger Tnp_zf-ribbon_2 PF13842.1 CDO70277.1 - 0.23 11.8 0.4 0.23 11.8 0.3 1.6 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-C2HC5 PF06221.8 CDO70277.1 - 0.65 9.7 3.8 0.77 9.5 1.8 1.8 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type BTG PF07742.7 CDO70278.1 - 2.7e-14 52.6 0.0 7.5e-14 51.2 0.0 1.7 2 0 0 2 2 2 1 BTG family BATS PF06968.8 CDO70279.1 - 2.5e-27 94.5 0.0 6.3e-27 93.2 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 CDO70279.1 - 2.5e-17 63.5 0.0 4.9e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily EPSP_synthase PF00275.15 CDO70279.1 - 0.15 10.4 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) BCAS2 PF05700.6 CDO70280.1 - 1.6e-45 155.3 4.8 2.5e-45 154.6 3.3 1.3 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) PDDEXK_1 PF12705.2 CDO70280.1 - 0.017 14.5 0.2 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Complex1_30kDa PF00329.14 CDO70281.1 - 1.4e-34 118.4 0.1 2.2e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF2087 PF09860.4 CDO70281.1 - 0.029 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF2413 PF10310.4 CDO70282.1 - 1.2e-77 261.6 1.3 4.4e-77 259.7 0.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) Chromo PF00385.19 CDO70283.1 - 6.9e-10 38.4 2.3 1.3e-09 37.6 1.6 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tim17 PF02466.14 CDO70284.1 - 6.4e-24 84.4 0.1 1.1e-23 83.6 0.1 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ras PF00071.17 CDO70285.1 - 1.8e-38 131.4 0.2 2.2e-38 131.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO70285.1 - 3.6e-07 30.6 0.0 6.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CDO70285.1 - 6.7e-05 22.4 0.0 8.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CDO70285.1 - 0.0023 17.2 0.1 0.0026 17.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Filo_VP35 PF02097.10 CDO70285.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Filoviridae VP35 DUF1814 PF08843.6 CDO70287.1 - 0.019 14.7 0.0 0.02 14.6 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) RVT_1 PF00078.22 CDO70290.1 - 5.2e-18 65.1 0.0 4.2e-16 58.9 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO70290.1 - 2e-13 50.8 0.0 3.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO70290.1 - 0.067 13.5 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase UPF0016 PF01169.14 CDO70291.1 - 3.6e-46 155.1 14.3 5e-23 81.0 2.0 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 CDO70291.1 - 0.0059 16.0 5.4 0.016 14.6 0.1 2.6 2 1 0 2 2 2 1 Integral membrane protein TerC family DUF2208 PF09973.4 CDO70291.1 - 0.078 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) TauE PF01925.14 CDO70291.1 - 0.084 12.3 11.4 4.7 6.5 7.9 2.1 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE LysE PF01810.13 CDO70291.1 - 1.4 8.1 13.2 0.39 9.9 1.6 2.3 2 0 0 2 2 2 0 LysE type translocator PNP_UDP_1 PF01048.15 CDO70292.1 - 1.7e-23 82.8 0.0 3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_tran_WecB PF03808.8 CDO70292.1 - 0.012 15.0 0.0 0.13 11.6 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family HMG_box PF00505.14 CDO70293.1 - 1.8e-13 50.5 4.2 3.7e-13 49.5 2.9 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO70293.1 - 2e-11 44.1 2.0 4.1e-11 43.0 1.4 1.5 1 0 0 1 1 1 1 HMG-box domain adh_short_C2 PF13561.1 CDO70294.1 - 1.5e-34 119.8 0.1 1.9e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO70294.1 - 2.8e-19 69.6 1.9 3.8e-19 69.1 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO70294.1 - 1.3e-09 37.9 0.4 1.8e-09 37.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 CDO70294.1 - 0.0019 17.2 0.1 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase His_biosynth PF00977.16 CDO70294.1 - 0.012 14.8 0.1 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein PA PF02225.17 CDO70294.1 - 0.051 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 PA domain Glyco_hydro_31 PF01055.21 CDO70295.1 - 1.6e-164 547.9 0.7 1.8e-164 547.7 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 RVT_1 PF00078.22 CDO70296.1 - 1e-22 80.5 0.3 1.7e-22 79.8 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO70296.1 - 0.0091 14.9 0.1 0.014 14.4 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CDO70297.1 - 9.7e-12 44.8 0.0 2.5e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotrans_gag PF03732.12 CDO70298.1 - 0.00028 20.8 0.1 0.00044 20.2 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Ric8 PF10165.4 CDO70301.1 - 7.3e-51 173.3 0.1 5.5e-37 127.6 0.0 2.7 2 1 0 2 2 2 2 Guanine nucleotide exchange factor synembryn His_Phos_1 PF00300.17 CDO70302.1 - 1.1e-10 41.8 0.0 1.2e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PPTA PF01239.17 CDO70303.1 - 0.1 11.9 0.4 0.18 11.2 0.3 1.3 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat CDC45 PF02724.9 CDO70305.1 - 0.12 10.4 10.1 0.13 10.2 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CDO70305.1 - 0.15 9.9 8.2 0.16 9.8 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.4 CDO70305.1 - 0.26 9.5 18.7 0.27 9.4 12.9 1.0 1 0 0 1 1 1 0 Transmembrane protein CobT PF06213.7 CDO70305.1 - 0.45 9.6 10.9 0.53 9.3 7.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.8 CDO70305.1 - 0.72 8.3 8.2 0.87 8.0 5.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BUD22 PF09073.5 CDO70305.1 - 3.2 6.7 20.7 4.2 6.3 14.4 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.6 CDO70305.1 - 3.4 5.4 16.7 4.6 4.9 11.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4207 PF13904.1 CDO70305.1 - 3.6 6.8 15.2 4.2 6.6 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Plasmodium_Vir PF05795.6 CDO70305.1 - 3.8 6.6 6.4 4.8 6.2 4.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1510 PF07423.6 CDO70305.1 - 6.4 6.0 10.2 7.7 5.8 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NOA36 PF06524.7 CDO70305.1 - 6.8 5.8 7.2 8.3 5.5 5.0 1.1 1 0 0 1 1 1 0 NOA36 protein Na_trans_assoc PF06512.8 CDO70305.1 - 7.3 6.4 10.3 8.9 6.2 7.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Apt1 PF10351.4 CDO70305.1 - 9.2 4.9 17.0 10 4.8 11.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sec63 PF02889.11 CDO70306.1 - 1.4e-27 96.7 0.0 2.2e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 CDO70306.1 - 3.1e-17 62.0 0.1 6.6e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain p450 PF00067.17 CDO70307.1 - 2e-07 29.9 0.0 5.9e-07 28.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 RA PF00788.18 CDO70308.1 - 2e-13 50.6 0.0 5.7e-10 39.5 0.0 3.8 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 CDO70308.1 - 1.9e-06 27.1 0.7 3.6e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CDO70308.1 - 0.00011 21.6 0.0 0.0003 20.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Clp1 PF06807.9 CDO70310.1 - 4.6e-13 49.3 0.0 7.3e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CDO70310.1 - 4.2e-07 29.7 0.0 7.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CDO70310.1 - 0.0092 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CDO70310.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase WGG PF10273.4 CDO70311.1 - 4.2e-26 90.8 0.0 7.2e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Ldh_1_C PF02866.13 CDO70312.1 - 4.3e-47 160.0 0.0 8.1e-47 159.1 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CDO70312.1 - 6.2e-36 123.3 0.4 2e-22 79.5 0.1 2.3 1 1 1 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CDO70312.1 - 0.007 16.6 1.4 0.077 13.3 0.1 2.8 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CDO70312.1 - 0.025 13.6 0.1 4 6.5 0.0 2.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Cyclin_N PF00134.18 CDO70314.1 - 3.7e-07 29.7 0.0 5.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CDO70314.1 - 0.00026 21.4 0.0 0.00068 20.0 0.0 1.8 1 1 0 1 1 1 1 Cyclin zf-C4H2 PF10146.4 CDO70315.1 - 1.1e-07 32.1 3.5 1.3e-07 31.9 2.4 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein DUF3450 PF11932.3 CDO70315.1 - 0.0015 17.8 7.2 0.0019 17.5 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF2379 PF09543.5 CDO70315.1 - 0.021 14.7 1.6 0.046 13.6 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Cullin PF00888.17 CDO70315.1 - 0.029 12.9 1.5 0.033 12.7 1.1 1.1 1 0 0 1 1 1 0 Cullin family Poty_PP PF08440.5 CDO70315.1 - 0.03 13.4 4.4 0.04 12.9 3.1 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein TMCO5 PF14992.1 CDO70315.1 - 0.034 13.2 9.5 0.043 12.9 6.6 1.1 1 0 0 1 1 1 0 TMCO5 family TBPIP PF07106.8 CDO70315.1 - 0.048 13.2 11.7 0.044 13.3 7.2 1.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 CDO70315.1 - 0.1 12.0 11.3 0.3 10.5 3.7 2.5 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 CDO70315.1 - 0.14 11.1 11.9 0.18 10.8 8.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 CDO70315.1 - 0.18 10.2 8.8 0.22 9.9 6.1 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 CDO70315.1 - 0.19 11.4 8.7 0.91 9.2 5.9 1.9 1 1 0 1 1 1 0 Laminin Domain II Lge1 PF11488.3 CDO70315.1 - 0.27 11.4 7.5 0.27 11.4 2.3 2.4 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 V_ATPase_I PF01496.14 CDO70315.1 - 1.1 7.0 4.9 1.3 6.8 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 CDO70315.1 - 1.6 8.4 16.9 0.47 10.1 7.5 2.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-Q PF13094.1 CDO70315.1 - 2.1 8.3 17.2 4.3 7.3 11.8 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Peptidase_S46 PF10459.4 CDO70315.1 - 3.4 5.9 8.8 4.2 5.6 6.1 1.0 1 0 0 1 1 1 0 Peptidase S46 Mnd1 PF03962.10 CDO70315.1 - 3.5 7.2 12.0 2.9 7.5 7.4 1.5 1 1 0 1 1 1 0 Mnd1 family IncA PF04156.9 CDO70315.1 - 4.1 6.9 15.8 6.6 6.2 10.9 1.3 1 1 0 1 1 1 0 IncA protein DUF724 PF05266.9 CDO70315.1 - 4.7 6.7 10.9 7.7 6.0 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GPI-anchored PF10342.4 CDO70316.1 - 0.0012 19.2 0.0 0.0031 17.9 0.0 1.6 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CDO70316.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 CDO70317.1 - 2.4e-06 27.9 0.0 3.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CDO70317.1 - 0.084 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) zf-C3HC4_3 PF13920.1 CDO70318.1 - 5.8e-09 35.4 16.2 5.8e-09 35.4 11.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PolC_DP2 PF03833.8 CDO70318.1 - 0.74 7.3 6.9 0.98 6.9 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 HSF_DNA-bind PF00447.12 CDO70320.1 - 4.2e-36 123.2 1.0 1e-35 122.0 0.7 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding IFT46_B_C PF12317.3 CDO70320.1 - 0.028 13.8 0.1 0.053 12.8 0.1 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal CENP-Q PF13094.1 CDO70320.1 - 0.044 13.8 0.3 0.044 13.8 0.2 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Snapin_Pallidin PF14712.1 CDO70320.1 - 0.059 13.6 1.6 0.15 12.4 1.1 1.7 1 0 0 1 1 1 0 Snapin/Pallidin FliD_C PF07195.7 CDO70320.1 - 0.08 12.2 1.7 0.41 9.9 0.4 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TPR_MLP1_2 PF07926.7 CDO70320.1 - 0.16 11.7 4.8 0.052 13.2 0.9 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 CDO70320.1 - 2.9 7.9 5.5 0.35 10.9 0.5 1.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family GOLGA2L5 PF15070.1 CDO70320.1 - 5.1 5.4 10.6 0.34 9.3 3.7 1.5 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 RVT_1 PF00078.22 CDO70323.1 - 9.5e-24 83.9 0.0 1.6e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO70323.1 - 2.2e-10 40.9 0.0 1.2e-09 38.6 0.0 2.1 2 0 0 2 2 2 1 RNase H Exo_endo_phos_2 PF14529.1 CDO70323.1 - 3.7e-10 39.4 0.0 9.6e-10 38.1 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Pkinase PF00069.20 CDO70324.1 - 0.089 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain zf-C2H2 PF00096.21 CDO70325.1 - 2.1e-05 24.5 1.4 0.12 12.7 0.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO70325.1 - 0.00042 20.4 2.4 0.069 13.5 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CDO70325.1 - 0.0018 18.3 2.6 0.11 12.6 0.1 2.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CDO70325.1 - 0.048 13.7 1.4 0.83 9.8 1.0 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CDO70325.1 - 0.17 12.0 1.6 2.1 8.5 0.9 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PAT1 PF09770.4 CDO70325.1 - 0.96 7.6 20.9 1.2 7.2 14.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_6 PF12697.2 CDO70326.1 - 1.3e-14 54.6 3.2 1.5e-13 51.2 2.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO70326.1 - 1.4e-07 31.3 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO70326.1 - 0.00016 21.3 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CDO70326.1 - 0.001 18.6 0.4 0.0034 17.0 0.1 1.9 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.7 CDO70326.1 - 0.016 14.5 0.0 0.04 13.2 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 CDO70326.1 - 0.099 12.2 0.0 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_8 PF06259.7 CDO70326.1 - 0.17 11.3 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase NAD_binding_10 PF13460.1 CDO70327.1 - 0.0077 16.2 0.0 0.62 10.0 0.0 2.1 1 1 1 2 2 2 2 NADH(P)-binding adh_short PF00106.20 CDO70327.1 - 0.0087 15.9 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.11 CDO70327.1 - 0.025 14.0 0.0 0.05 13.0 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ATP-synt_J PF04911.7 CDO70328.1 - 6.8e-19 67.0 0.8 1.4e-18 66.0 0.1 1.7 2 0 0 2 2 2 1 ATP synthase j chain Clathrin PF00637.15 CDO70329.1 - 2.9e-16 59.3 0.0 1.6e-11 43.9 0.3 2.8 3 0 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.3 CDO70329.1 - 0.0013 18.5 0.1 0.0029 17.4 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal TPR_11 PF13414.1 CDO70329.1 - 0.0092 15.6 0.7 0.054 13.1 0.0 2.7 3 0 0 3 3 3 1 TPR repeat zf-RING_2 PF13639.1 CDO70329.1 - 0.036 13.9 7.6 0.065 13.0 5.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CDO70329.1 - 0.13 12.2 6.8 0.24 11.4 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO70329.1 - 0.46 10.2 7.2 0.8 9.4 5.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain TPR_16 PF13432.1 CDO70329.1 - 0.75 10.5 9.8 11 6.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-rbx1 PF12678.2 CDO70329.1 - 5.7 7.1 6.9 11 6.2 4.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger NmrA PF05368.8 CDO70330.1 - 1.1e-42 145.9 0.0 1.3e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CDO70330.1 - 9.4e-14 51.8 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CDO70330.1 - 1.4e-06 27.2 0.0 2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 CDO70330.1 - 0.00018 21.5 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 CDO70330.1 - 0.00053 19.6 0.1 0.00089 18.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CDO70330.1 - 0.0021 18.0 0.1 0.0034 17.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 CDO70330.1 - 0.0047 15.9 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 CDO70330.1 - 0.01 15.2 0.0 0.082 12.3 0.0 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CDO70330.1 - 0.015 15.6 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 CDO70330.1 - 0.024 15.1 0.0 0.045 14.3 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 CDO70330.1 - 0.025 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 CDO70330.1 - 0.045 14.1 0.0 0.073 13.5 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent BTB PF00651.26 CDO70331.1 - 5.5e-12 45.6 0.0 7.3e-05 22.7 0.0 3.4 3 0 0 3 3 3 2 BTB/POZ domain BTB PF00651.26 CDO70332.1 - 1.8e-05 24.6 0.0 4.6e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain SMC_N PF02463.14 CDO70333.1 - 1.2e-53 181.5 0.0 3.4e-30 104.9 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CDO70333.1 - 9.2e-32 109.5 0.1 6e-31 106.9 0.0 2.6 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CDO70333.1 - 4.7e-13 49.7 0.1 6.8e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain NAD_binding_1 PF00175.16 CDO70333.1 - 2.1e-11 44.3 4.7 5.6e-11 42.9 0.0 3.6 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Globin PF00042.17 CDO70333.1 - 4.4e-07 30.2 2.1 1.3e-06 28.6 0.1 2.7 2 0 0 2 2 2 1 Globin AAA_29 PF13555.1 CDO70333.1 - 7.2e-07 28.6 0.0 1.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FAD_binding_6 PF00970.19 CDO70333.1 - 6.7e-05 22.9 0.0 0.00021 21.3 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CDO70333.1 - 0.024 14.5 0.0 0.31 10.9 0.0 3.0 2 0 0 2 2 2 0 Ferric reductase NAD binding domain ABC_tran PF00005.22 CDO70333.1 - 0.29 11.4 0.0 0.29 11.4 0.0 5.6 4 1 1 5 5 5 0 ABC transporter AAA_15 PF13175.1 CDO70333.1 - 0.29 10.1 0.0 0.29 10.1 0.0 4.2 3 1 1 4 4 4 0 AAA ATPase domain SpoIISA_toxin PF14171.1 CDO70333.1 - 8.9 5.4 6.1 8.6 5.5 1.5 2.4 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system 4HBT PF03061.17 CDO70334.1 - 1e-06 28.7 0.4 1.7e-06 28.0 0.3 1.4 1 0 0 1 1 1 1 Thioesterase superfamily MFS_1 PF07690.11 CDO70336.1 - 4.7e-38 130.7 34.1 6.4e-38 130.3 23.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO70336.1 - 5.7e-17 61.4 13.4 5.7e-17 61.4 9.3 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CDO70336.1 - 9.8e-08 30.6 0.9 1.4e-07 30.1 0.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.6 CDO70336.1 - 0.026 13.8 1.1 0.035 13.4 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Y_phosphatase3 PF13350.1 CDO70337.1 - 9.9e-44 149.4 0.1 1.7e-43 148.7 0.1 1.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 CDO70337.1 - 1.5e-09 37.7 0.3 3.5e-08 33.4 0.0 2.8 3 0 0 3 3 3 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 CDO70337.1 - 1.3e-05 24.6 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 CDO70337.1 - 0.00019 20.8 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CDO70337.1 - 0.0012 18.9 0.0 0.0042 17.1 0.0 2.0 1 1 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 CDO70337.1 - 0.0043 16.6 0.1 0.018 14.6 0.0 2.2 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain KNOX2 PF03791.8 CDO70337.1 - 0.0082 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 KNOX2 domain Glyco_trans_4_4 PF13579.1 CDO70337.1 - 0.012 15.8 2.4 0.029 14.5 1.7 1.8 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Peptidase_C14 PF00656.17 CDO70340.1 - 4.5e-43 147.7 0.0 7.2e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Pkinase PF00069.20 CDO70341.1 - 7.9e-52 175.9 0.0 2.9e-51 174.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70341.1 - 1e-22 80.4 0.0 1.4e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO70341.1 - 0.00028 19.9 0.0 0.0026 16.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CDO70341.1 - 0.0047 16.7 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CDO70341.1 - 0.027 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CDO70341.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DSPc PF00782.15 CDO70346.1 - 1.7e-05 24.3 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDO70346.1 - 0.0019 17.5 0.1 0.0021 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CDO70346.1 - 0.043 14.0 1.0 0.059 13.6 0.4 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.7 CDO70346.1 - 0.061 12.7 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF2216 PF10226.4 CDO70347.1 - 0.1 12.0 0.7 0.11 11.9 0.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) PPR_2 PF13041.1 CDO70351.1 - 4.9e-43 144.8 0.0 1.8e-14 53.3 0.1 12.0 10 3 3 13 13 13 8 PPR repeat family PPR PF01535.15 CDO70351.1 - 1.7e-40 134.2 0.1 6.3e-05 22.6 0.0 13.1 14 0 0 14 14 14 6 PPR repeat PPR_3 PF13812.1 CDO70351.1 - 8.9e-33 109.8 19.9 0.00021 21.3 0.0 15.1 16 0 0 16 16 16 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 CDO70351.1 - 1.4e-31 107.6 0.1 2.2e-06 27.0 0.0 10.6 11 0 0 11 11 11 6 PPR repeat TPR_14 PF13428.1 CDO70351.1 - 1.4e-09 37.7 22.5 2.9 8.7 0.1 11.8 13 1 0 13 13 13 3 Tetratricopeptide repeat TPR_7 PF13176.1 CDO70351.1 - 0.00013 21.5 0.1 10 6.1 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 CDO70351.1 - 0.079 13.4 13.2 21 5.9 0.4 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Exo_endo_phos_2 PF14529.1 CDO70351.1 - 0.17 11.4 0.9 0.6 9.7 0.1 2.3 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Thioredoxin PF00085.15 CDO70352.1 - 8.8e-49 163.5 0.0 5.6e-25 87.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CDO70352.1 - 2.6e-09 37.2 2.0 2.9e-06 27.4 0.1 3.2 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDO70352.1 - 3.7e-08 33.3 0.1 0.0029 17.6 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CDO70352.1 - 0.00023 21.1 0.0 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.1 CDO70352.1 - 0.0024 17.8 0.3 0.059 13.3 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 CDO70352.1 - 0.012 15.4 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_9 PF14595.1 CDO70352.1 - 0.034 13.6 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin AhpC-TSA PF00578.16 CDO70352.1 - 0.082 12.5 0.1 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family SCO1-SenC PF02630.9 CDO70353.1 - 2.3e-55 186.8 0.0 3.4e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC CGI-121 PF08617.5 CDO70353.1 - 5.7e-19 68.3 0.0 9.3e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Kinase binding protein CGI-121 AhpC-TSA PF00578.16 CDO70353.1 - 3.8e-05 23.3 0.0 9.1e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 CDO70353.1 - 0.0083 16.2 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like DUF2762 PF10960.3 CDO70353.1 - 0.12 12.0 0.1 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) NDUF_B7 PF05676.8 CDO70354.1 - 2e-19 68.7 7.2 4.1e-18 64.5 5.0 2.0 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 CDO70354.1 - 0.057 13.1 4.8 0.077 12.7 3.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 CDO70354.1 - 0.1 12.6 1.2 0.14 12.2 0.8 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 VWA_2 PF13519.1 CDO70355.1 - 3e-14 53.4 1.6 6.7e-14 52.3 1.1 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 CDO70355.1 - 1.8e-11 42.5 14.7 0.00059 19.1 0.1 3.6 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 CDO70355.1 - 3.8e-05 23.3 0.1 0.00011 21.9 0.0 1.7 2 0 0 2 2 2 1 Ssl1-like FAM53 PF15242.1 CDO70355.1 - 0.42 10.1 7.6 0.64 9.5 5.2 1.2 1 0 0 1 1 1 0 Family of FAM53 CytochromB561_N PF09786.4 CDO70355.1 - 4.9 5.4 6.0 7.2 4.9 4.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF2611 PF11022.3 CDO70355.1 - 7.8 6.6 8.3 39 4.4 5.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2611) MRI PF15325.1 CDO70355.1 - 8.9 7.3 14.8 2.1 9.3 6.8 2.1 1 1 1 2 2 2 0 Modulator of retrovirus infection Actin PF00022.14 CDO70356.1 - 3.1e-150 500.0 0.0 3.5e-150 499.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CDO70356.1 - 0.074 13.4 0.0 0.18 12.2 0.0 1.6 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PhoPQ_related PF10142.4 CDO70357.1 - 0.0025 16.3 0.0 0.0036 15.8 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein CBM_1 PF00734.13 CDO70358.1 - 1.5e-14 53.3 8.9 1.5e-14 53.3 6.2 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Amidohydro_2 PF04909.9 CDO70359.1 - 0.0017 17.9 0.1 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Frigida PF07899.6 CDO70359.1 - 0.088 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Frigida-like protein PPP4R2 PF09184.6 CDO70360.1 - 1.9 7.9 12.4 2.1 7.8 8.6 1.1 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.7 CDO70360.1 - 3.4 6.8 15.3 3.7 6.7 10.6 1.0 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.7 CDO70360.1 - 4.6 5.4 12.8 4.8 5.4 8.9 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop25 PF09805.4 CDO70360.1 - 5.1 7.1 10.1 5.9 6.9 7.0 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Daxx PF03344.10 CDO70360.1 - 5.4 5.3 14.8 5.6 5.3 10.3 1.0 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 CDO70360.1 - 6.2 6.4 10.3 7 6.2 7.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Prothymosin PF03247.9 CDO70360.1 - 6.3 6.9 24.3 9.3 6.4 16.9 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family NOA36 PF06524.7 CDO70360.1 - 7.1 5.7 13.2 8.3 5.5 9.1 1.2 1 0 0 1 1 1 0 NOA36 protein HSBP1 PF06825.7 CDO70362.1 - 0.0028 17.1 1.8 0.49 10.0 0.2 2.9 3 0 0 3 3 3 2 Heat shock factor binding protein 1 Phage_GPO PF05929.6 CDO70362.1 - 0.0088 15.3 0.5 0.013 14.7 0.3 1.3 1 1 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase Dynamitin PF04912.9 CDO70362.1 - 0.01 14.6 0.8 0.022 13.5 0.6 1.7 1 1 0 1 1 1 0 Dynamitin F-box-like PF12937.2 CDO70364.1 - 0.0022 17.6 0.0 0.0084 15.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO70364.1 - 0.024 14.2 0.1 0.024 14.2 0.1 2.2 3 0 0 3 3 3 0 F-box domain DUF155 PF02582.9 CDO70365.1 - 3.1e-42 144.4 0.0 4.5e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DEAD PF00270.24 CDO70366.1 - 3.9e-38 130.5 0.1 3.8e-18 65.5 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO70366.1 - 5.4e-24 83.8 0.0 9.5e-23 79.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO70366.1 - 0.0082 15.9 0.0 0.022 14.5 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4177 PF13783.1 CDO70367.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4177) DUF2135 PF09906.4 CDO70370.1 - 0.053 13.4 0.1 0.22 11.4 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2135) zf-C2H2_4 PF13894.1 CDO70371.1 - 2.2e-05 24.4 7.1 0.0036 17.5 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO70371.1 - 6.5e-05 23.0 7.6 0.0058 16.9 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO70371.1 - 0.00079 19.5 8.9 0.0015 18.7 1.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-H2C2_5 PF13909.1 CDO70371.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 CDO70371.1 - 0.72 10.0 3.0 17 5.6 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RRM_1 PF00076.17 CDO70372.1 - 1.4e-39 133.5 0.0 3.7e-19 68.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO70372.1 - 4.8e-24 84.1 0.0 2.9e-13 49.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO70372.1 - 3.6e-15 55.5 0.0 1.2e-07 31.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CDO70372.1 - 1.7e-07 30.7 2.1 0.00053 19.6 0.0 3.3 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 CDO70372.1 - 0.018 14.8 0.2 6.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 PAM2 PF07145.10 CDO70372.1 - 0.054 13.0 5.2 0.026 13.9 0.9 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Nup35_RRM PF05172.8 CDO70372.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MFS_1 PF07690.11 CDO70373.1 - 2e-18 66.2 23.3 2e-18 66.2 16.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 CDO70374.1 - 3.7e-11 42.6 0.0 1.9e-10 40.3 0.0 2.2 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 CDO70374.1 - 4.7e-06 26.5 3.5 1.2e-05 25.2 2.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO70374.1 - 1e-05 24.6 5.4 0.00075 18.5 4.0 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CDO70374.1 - 7.6e-05 23.0 1.3 0.00016 22.0 0.9 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO70374.1 - 0.00042 18.8 0.5 0.00066 18.2 0.3 1.3 1 1 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 CDO70374.1 - 0.00057 19.0 0.9 0.00057 19.0 0.6 1.6 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 CDO70374.1 - 0.0011 18.1 0.4 0.17 10.9 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 CDO70374.1 - 0.045 13.6 1.2 0.076 12.8 0.9 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 CDO70374.1 - 0.053 12.8 0.8 0.096 12.0 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.19 CDO70374.1 - 0.059 12.2 5.4 0.094 11.5 3.7 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 CDO70374.1 - 0.082 12.5 2.1 0.15 11.6 1.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 CDO70374.1 - 0.085 11.4 2.5 0.12 11.0 1.7 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Syndecan PF01034.15 CDO70374.1 - 0.098 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Pyr_redox_3 PF13738.1 CDO70374.1 - 0.12 12.4 1.7 0.42 10.6 1.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CDO70374.1 - 0.12 11.8 1.5 0.22 10.9 1.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA B5 PF03484.10 CDO70374.1 - 0.16 11.8 0.1 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetase B5 domain GIDA PF01134.17 CDO70374.1 - 0.19 10.5 3.2 0.27 10.0 2.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 CDO70374.1 - 0.58 9.9 2.8 3.1 7.5 1.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sterol_MT_C PF08498.5 CDO70375.1 - 1.9e-25 88.5 0.0 3.4e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 CDO70375.1 - 4.2e-18 65.3 0.0 6.4e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO70375.1 - 8.9e-17 61.3 0.0 1.6e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CDO70375.1 - 2.6e-14 52.9 0.0 3.4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CDO70375.1 - 1e-12 48.0 0.0 2.5e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO70375.1 - 2.3e-12 47.4 0.0 1.1e-11 45.2 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO70375.1 - 1.4e-10 41.5 0.0 3.9e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO70375.1 - 1.4e-10 41.2 0.0 3.9e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO70375.1 - 2.4e-09 37.4 0.0 4.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDO70375.1 - 1.2e-07 31.0 0.0 2.3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 CDO70375.1 - 9.1e-05 21.6 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 CDO70375.1 - 0.00017 21.1 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CDO70375.1 - 0.00039 19.8 0.0 0.00066 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 CDO70375.1 - 0.00064 19.3 0.0 0.00093 18.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.7 CDO70375.1 - 0.0071 15.7 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 CDO70375.1 - 0.022 15.5 0.0 0.16 12.8 0.0 2.3 3 0 0 3 3 2 0 Methyltransferase domain Met_10 PF02475.11 CDO70375.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.13 CDO70375.1 - 0.053 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 CDO70375.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) p450 PF00067.17 CDO70376.1 - 3e-07 29.3 0.0 5.1e-07 28.5 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 p450 PF00067.17 CDO70377.1 - 1.7e-42 145.5 0.0 2.2e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.20 CDO70377.1 - 1.2e-15 57.7 0.0 1.9e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 CDO70378.1 - 1.6e-12 47.3 0.0 2.1e-11 43.7 0.0 1.9 1 1 1 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 CDO70378.1 - 4.7e-12 46.4 0.0 8e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CDO70378.1 - 0.12 12.2 0.0 10 6.0 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Het-C PF07217.6 CDO70379.1 - 1.1e-191 638.1 0.0 1e-119 400.4 0.0 3.6 3 1 0 3 3 3 3 Heterokaryon incompatibility protein Het-C NTF2 PF02136.15 CDO70380.1 - 6.5e-27 94.2 0.1 1.1e-26 93.5 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 CDO70380.1 - 1.8e-10 40.2 0.0 3.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO70380.1 - 1.2e-05 25.0 0.1 3.3e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO70380.1 - 0.00018 21.3 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CDO70381.1 - 9.3e-62 202.8 13.1 1.4e-13 50.1 0.1 12.2 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.7 CDO70381.1 - 1.8e-24 85.7 0.0 2.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 CDO70381.1 - 3.4e-06 26.9 1.3 0.29 10.8 0.1 5.2 4 2 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 CDO70381.1 - 9.6e-05 21.8 0.0 0.2 11.0 0.0 3.7 2 2 2 4 4 4 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 CDO70381.1 - 0.00028 19.1 1.3 0.34 8.9 0.1 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 CDO70381.1 - 0.012 15.2 1.7 13 5.5 0.0 4.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 CDO70381.1 - 0.017 13.0 0.0 2.4 5.8 0.0 3.3 3 2 1 4 4 4 0 IKI3 family DUF1513 PF07433.6 CDO70381.1 - 0.021 13.7 0.1 4.6 6.0 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 CDO70381.1 - 0.023 12.9 0.1 25 3.0 0.0 3.4 3 0 0 3 3 3 0 Cytochrome D1 heme domain RRM_1 PF00076.17 CDO70381.1 - 0.045 13.3 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 CDO70382.1 - 2.4e-101 339.5 18.5 2.8e-101 339.3 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO70382.1 - 6.7e-32 110.5 32.5 3.9e-23 81.7 9.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 CDO70382.1 - 0.0094 14.6 0.9 0.0094 14.6 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 CDO70382.1 - 0.039 13.7 1.1 1.7 8.4 0.0 3.5 3 0 0 3 3 3 0 MFS_1 like family Alpha-L-AF_C PF06964.7 CDO70383.1 - 1.3e-29 103.2 0.0 2e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus zf-C2H2_4 PF13894.1 CDO70384.1 - 0.017 15.3 4.1 2.1 8.8 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO70384.1 - 8.4 6.9 9.8 0.44 10.9 0.3 2.8 2 1 0 2 2 2 0 Zinc finger, C2H2 type Rad52_Rad22 PF04098.10 CDO70385.1 - 3.4e-58 195.7 0.0 5.7e-58 195.0 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein zf-H2C2_2 PF13465.1 CDO70388.1 - 0.00051 20.1 5.7 0.021 15.0 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 CDO70388.1 - 0.0036 17.5 11.1 0.082 13.2 1.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO70388.1 - 0.098 13.0 8.2 1.5 9.3 0.8 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger DUF4366 PF14283.1 CDO70389.1 - 0.038 13.3 0.8 0.088 12.2 0.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4366) AA_permease_2 PF13520.1 CDO70392.1 - 6.7e-39 133.6 41.8 1.9e-33 115.6 14.3 2.6 1 1 1 2 2 2 2 Amino acid permease DUF4293 PF14126.1 CDO70392.1 - 0.085 12.7 0.1 0.085 12.7 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Pkinase PF00069.20 CDO70393.1 - 9.4e-48 162.6 0.0 1.4e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70393.1 - 1.5e-44 151.9 0.0 3e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CDO70393.1 - 8.4e-08 31.8 1.0 1.7e-07 30.8 0.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 CDO70393.1 - 0.0099 15.6 0.1 0.025 14.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CDO70393.1 - 0.012 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 CDO70393.1 - 0.046 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-Mss51 PF13824.1 CDO70393.1 - 0.054 13.3 1.9 0.24 11.3 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 PHD PF00628.24 CDO70393.1 - 0.12 12.1 5.1 0.23 11.1 3.6 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 CDO70393.1 - 0.2 11.4 3.9 0.44 10.3 2.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Arginosuc_synth PF00764.14 CDO70394.1 - 2.4e-153 510.8 0.0 2.8e-153 510.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 CDO70394.1 - 0.00023 20.5 0.0 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 CDO70394.1 - 0.0033 16.9 0.0 0.0047 16.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 CDO70394.1 - 0.03 12.8 0.0 0.047 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Noc2 PF03715.8 CDO70395.1 - 8.3e-101 336.7 0.0 1.4e-100 336.0 0.0 1.4 1 0 0 1 1 1 1 Noc2p family HSP70 PF00012.15 CDO70397.1 - 0.022 12.6 0.0 0.089 10.6 0.0 1.9 2 0 0 2 2 2 0 Hsp70 protein ALO PF04030.9 CDO70398.1 - 2e-80 270.1 0.0 2.8e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CDO70398.1 - 1.2e-26 92.8 0.1 4.3e-26 91.0 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain UQ_con PF00179.21 CDO70399.1 - 8.4e-39 132.2 0.0 1.1e-27 96.1 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UQ_con PF00179.21 CDO70401.1 - 7e-45 151.9 0.0 8.1e-45 151.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDO70401.1 - 0.0098 15.6 0.0 0.023 14.4 0.0 1.7 1 1 0 1 1 1 1 Prokaryotic E2 family B UPF0261 PF06792.6 CDO70402.1 - 6.3e-139 462.9 0.0 7.6e-139 462.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 CDO70403.1 - 1.2e-87 293.3 1.1 1.4e-87 293.1 0.8 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein Acetate_kinase PF00871.12 CDO70403.1 - 0.092 11.2 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Acetokinase family Got1 PF04178.7 CDO70404.1 - 7.5e-29 100.2 13.1 9.8e-29 99.8 9.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3357 PF11837.3 CDO70404.1 - 0.16 11.8 0.2 3 7.7 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF2157 PF09925.4 CDO70404.1 - 0.28 10.7 12.2 0.14 11.7 4.1 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF2975 PF11188.3 CDO70404.1 - 8.2 6.1 12.8 0.36 10.5 3.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF3414 PF11894.3 CDO70405.1 - 1.3e-264 880.9 0.0 1.7e-264 880.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Myosin_head PF00063.16 CDO70405.1 - 0.98 7.3 0.0 1.7 6.5 0.0 1.3 1 0 0 1 1 1 0 Myosin head (motor domain) Acetyltransf_1 PF00583.19 CDO70406.1 - 2.2e-17 62.8 0.0 3.2e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CDO70406.1 - 4.6e-10 39.1 0.1 6.5e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CDO70406.1 - 3.7e-09 36.7 0.0 5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CDO70406.1 - 4.2e-08 33.2 0.0 7.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CDO70406.1 - 2.8e-07 30.5 0.0 3.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CDO70406.1 - 5.1e-07 29.9 0.0 6.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CDO70406.1 - 5.2e-06 26.3 0.1 7.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CDO70406.1 - 0.0003 20.7 0.0 0.00038 20.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CDO70406.1 - 0.015 14.8 0.3 0.02 14.4 0.2 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CDO70406.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase HSP70 PF00012.15 CDO70407.1 - 1e-267 888.9 7.2 1.2e-267 888.7 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CDO70407.1 - 1.3e-19 70.0 0.5 6.9e-19 67.5 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 CDO70407.1 - 0.00097 18.0 0.2 0.061 12.1 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain 4HBT PF03061.17 CDO70407.1 - 0.019 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily FGGY_C PF02782.11 CDO70407.1 - 0.037 13.6 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Spectrin PF00435.16 CDO70407.1 - 0.15 12.3 6.9 6 7.2 0.1 3.4 3 1 0 3 3 3 0 Spectrin repeat Hydantoinase_A PF01968.13 CDO70407.1 - 0.17 10.9 3.4 0.1 11.6 0.2 2.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase 4HBT PF03061.17 CDO70408.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily RAP1 PF07218.6 CDO70411.1 - 0.51 8.3 8.2 0.61 8.1 5.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MT-A70 PF05063.9 CDO70412.1 - 1.9e-37 128.4 0.0 5.8e-37 126.9 0.0 1.7 1 1 0 1 1 1 1 MT-A70 tRNA-synt_1 PF00133.17 CDO70413.1 - 2.4e-38 131.5 0.0 9.6e-29 99.8 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) SNF2_N PF00176.18 CDO70413.1 - 2.8e-37 128.1 0.0 5.3e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain tRNA-synt_1g PF09334.6 CDO70413.1 - 8.4e-18 64.1 0.1 1.5e-09 37.0 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) Helicase_C PF00271.26 CDO70413.1 - 1e-14 54.1 0.0 1.5e-13 50.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Anticodon_1 PF08264.8 CDO70413.1 - 7.8e-14 51.7 1.6 9.3e-14 51.4 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CDO70413.1 - 1.1e-07 31.2 0.0 2.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain HDA2-3 PF11496.3 CDO70413.1 - 0.0015 17.3 0.0 0.0051 15.6 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 MFS_1 PF07690.11 CDO70414.1 - 5.4e-12 45.0 42.2 1e-11 44.1 28.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Oxysterol_BP PF01237.13 CDO70415.1 - 8.4e-76 254.7 0.1 1.5e-75 253.9 0.1 1.3 1 1 0 1 1 1 1 Oxysterol-binding protein COX5B PF01215.14 CDO70416.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb SurE PF01975.12 CDO70417.1 - 3.6e-21 75.3 1.3 5.9e-21 74.6 0.9 1.3 1 0 0 1 1 1 1 Survival protein SurE SurE PF01975.12 CDO70418.1 - 6.6e-22 77.7 1.3 1.1e-21 77.0 0.9 1.3 1 0 0 1 1 1 1 Survival protein SurE KRTAP7 PF15034.1 CDO70418.1 - 0.02 15.5 0.2 0.048 14.3 0.1 1.6 1 0 0 1 1 1 0 KRTAP type 7 family Kelch_4 PF13418.1 CDO70419.1 - 8.8e-46 153.4 14.1 3.3e-08 33.1 0.1 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CDO70419.1 - 4.2e-41 138.2 11.8 2.4e-08 33.9 0.0 6.9 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 CDO70419.1 - 1.6e-34 117.1 7.5 9.9e-07 28.2 0.1 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 CDO70419.1 - 2.1e-32 110.5 10.6 6.1e-09 35.6 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 CDO70419.1 - 7.1e-27 92.4 10.2 7.8e-06 25.8 0.0 6.0 5 2 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CDO70419.1 - 5.6e-24 82.9 14.9 7.7e-07 28.6 0.1 5.9 6 1 0 6 6 6 5 Kelch motif SMP PF04927.7 CDO70420.1 - 0.0002 21.2 25.9 0.015 15.2 0.9 5.4 5 1 0 5 5 5 4 Seed maturation protein HMG_box PF00505.14 CDO70421.1 - 4.2e-24 84.5 1.1 6.7e-24 83.9 0.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO70421.1 - 5.2e-19 68.3 1.6 9.6e-19 67.5 1.1 1.4 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 CDO70421.1 - 0.00073 19.1 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.8 CDO70421.1 - 0.0037 17.5 0.1 0.0044 17.2 0.1 1.3 1 0 0 1 1 1 1 YABBY protein HMG_box_5 PF14887.1 CDO70421.1 - 0.009 15.7 2.9 0.009 15.7 2.0 1.9 1 1 1 2 2 2 1 HMG (high mobility group) box 5 Peptidase_C65 PF10275.4 CDO70422.1 - 9.3e-68 228.1 0.0 1.2e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 CDO70422.1 - 2.7e-05 24.7 0.0 0.00066 20.2 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease MMS22L_C PF14911.1 CDO70422.1 - 0.19 10.7 0.3 0.44 9.5 0.1 1.6 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal PseudoU_synth_1 PF01416.15 CDO70423.1 - 0.0008 19.8 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridine synthase Mst1_SARAH PF11629.3 CDO70423.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Aminotran_4 PF01063.14 CDO70424.1 - 1e-10 41.4 0.0 2.6e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class IV SurE PF01975.12 CDO70425.1 - 1.9e-29 102.3 0.1 5.2e-29 100.9 0.0 1.6 1 1 0 1 1 1 1 Survival protein SurE SMP PF04927.7 CDO70427.1 - 1.5e-05 24.8 7.6 0.0022 17.9 0.1 4.3 4 0 0 4 4 4 2 Seed maturation protein Peptidase_M28 PF04389.12 CDO70428.1 - 0.0037 17.0 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Oxidored_q1_N PF00662.15 CDO70429.1 - 0.017 14.6 2.0 0.017 14.6 1.4 2.6 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Amino_oxidase PF01593.19 CDO70430.1 - 4.1e-56 190.9 0.5 1.6e-43 149.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CDO70430.1 - 2.2e-08 34.0 0.2 2.2e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO70430.1 - 1.3e-05 24.2 0.9 0.00019 20.4 0.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CDO70430.1 - 0.00086 19.6 1.0 0.02 15.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CDO70430.1 - 0.0015 17.6 0.9 0.0024 16.9 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CDO70430.1 - 0.0021 18.1 0.8 0.035 14.1 0.4 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CDO70430.1 - 0.0029 16.7 1.0 0.004 16.2 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 CDO70430.1 - 0.0093 16.0 0.2 0.017 15.1 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 CDO70430.1 - 0.035 12.9 1.4 0.058 12.2 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain Amidohydro_2 PF04909.9 CDO70431.1 - 9e-33 113.9 0.0 1.5e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 CDO70431.1 - 0.0026 17.0 0.0 0.0059 15.8 0.0 1.6 2 0 0 2 2 2 1 TatD related DNase BolA PF01722.13 CDO70433.1 - 9e-17 60.8 0.0 6.1e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 BolA-like protein Pkinase PF00069.20 CDO70434.1 - 2.3e-57 194.1 0.0 4.2e-57 193.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70434.1 - 3.6e-30 104.9 0.0 2.2e-19 69.5 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CDO70434.1 - 3.8e-05 23.5 0.0 0.00014 21.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CDO70434.1 - 8.1e-05 21.7 0.0 0.14 11.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CDO70434.1 - 0.0026 16.8 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CDO70434.1 - 0.05 12.9 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family SMP PF04927.7 CDO70435.1 - 8.1e-07 28.9 33.7 0.002 18.0 0.2 6.9 5 4 0 5 5 5 5 Seed maturation protein Atg31 PF09795.4 CDO70435.1 - 0.02 14.6 0.0 0.9 9.2 0.0 3.1 2 2 2 4 4 4 0 Autophagy-related protein 31 Ifi-6-16 PF06140.8 CDO70435.1 - 0.11 12.2 0.9 17 5.2 0.0 3.7 4 0 0 4 4 4 0 Interferon-induced 6-16 family rve_3 PF13683.1 CDO70435.1 - 1.3 8.5 4.6 1.4e+02 2.0 0.0 4.1 4 0 0 4 4 4 0 Integrase core domain RrnaAD PF00398.15 CDO70436.1 - 4.8e-59 199.5 0.1 6.6e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CDO70436.1 - 1.2e-10 41.4 0.0 2.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO70436.1 - 5e-07 30.3 0.0 1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDO70436.1 - 8.8e-06 25.2 0.2 2.4e-05 23.7 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CDO70436.1 - 9.4e-06 25.2 0.0 3.4e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 CDO70436.1 - 2.2e-05 23.7 0.1 0.00028 20.1 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase PCMT PF01135.14 CDO70436.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 CDO70436.1 - 0.00014 22.2 0.0 0.00043 20.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO70436.1 - 0.00042 20.0 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO70436.1 - 0.00058 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CDO70436.1 - 0.0017 17.4 0.0 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 CDO70436.1 - 0.018 13.9 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase Met_10 PF02475.11 CDO70436.1 - 0.021 14.3 0.0 0.063 12.8 0.0 1.7 2 0 0 2 2 2 0 Met-10+ like-protein Ubie_methyltran PF01209.13 CDO70436.1 - 0.034 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.6 CDO70436.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Trs65 PF12735.2 CDO70437.1 - 5.6 6.1 6.8 9 5.5 4.7 1.4 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Pkinase PF00069.20 CDO70439.1 - 1.5e-05 24.2 0.0 3.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TFIIE_beta PF02186.10 CDO70440.1 - 0.0053 16.7 0.5 0.012 15.6 0.1 1.8 2 0 0 2 2 2 1 TFIIE beta subunit core domain HSP20 PF00011.16 CDO70441.1 - 5e-24 84.1 0.0 6.3e-24 83.7 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 CDO70441.1 - 0.047 14.2 0.0 0.081 13.4 0.0 1.4 1 1 0 1 1 1 0 CS domain BON PF04972.12 CDO70441.1 - 0.11 12.3 0.1 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 BON domain VLPT PF07122.6 CDO70441.1 - 0.11 12.2 0.1 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Variable length PCR target protein (VLPT) Amidohydro_3 PF07969.6 CDO70442.1 - 6.1e-37 127.8 0.2 7.3e-37 127.5 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 CDO70442.1 - 9.1e-07 28.8 0.0 9.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CDO70442.1 - 0.021 14.8 0.4 0.072 13.1 0.1 1.9 1 1 1 2 2 2 0 Amidohydrolase Amidohydro_3 PF07969.6 CDO70443.1 - 8.6e-25 87.7 0.4 1.1e-24 87.3 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CDO70443.1 - 0.00051 19.7 0.0 0.0017 18.1 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase PPR_3 PF13812.1 CDO70444.1 - 2.6e-15 55.3 3.3 0.0069 16.5 0.1 7.4 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 CDO70444.1 - 2.7e-10 40.0 0.0 0.0068 16.3 0.0 4.7 4 0 0 4 4 4 3 PPR repeat family PPR PF01535.15 CDO70444.1 - 0.00017 21.3 3.5 12 6.1 0.0 6.1 6 1 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 CDO70444.1 - 0.18 11.3 0.0 12 5.5 0.0 3.1 3 0 0 3 3 3 0 PPR repeat Saccharop_dh_N PF04455.7 CDO70444.1 - 0.18 11.9 0.1 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 LOR/SDH bifunctional enzyme conserved region Bromo_TP PF07524.8 CDO70445.1 - 4.3e-07 29.5 0.5 2.8e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated CTP_transf_2 PF01467.21 CDO70446.1 - 1.8e-07 31.3 0.9 3.9e-06 26.9 0.6 2.3 1 1 0 1 1 1 1 Cytidylyltransferase DUF159 PF02586.9 CDO70447.1 - 6.9e-50 169.4 0.0 1.1e-49 168.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 CUE PF02845.11 CDO70448.1 - 7.4e-08 31.7 0.0 1.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain DSPc PF00782.15 CDO70449.1 - 1.3e-25 89.4 0.0 2.2e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 CDO70449.1 - 8e-07 29.3 0.0 5.5e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 CDO70449.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CDO70449.1 - 0.048 13.7 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 CDO70449.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LSM PF01423.17 CDO70450.1 - 1.6e-16 59.6 0.0 2e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain Shadoo PF14999.1 CDO70450.1 - 0.47 10.3 5.8 0.69 9.7 4.0 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective HEAT PF02985.17 CDO70451.1 - 3.3e-19 67.1 18.6 0.0013 18.6 0.0 12.1 12 2 1 13 13 13 3 HEAT repeat HEAT_EZ PF13513.1 CDO70451.1 - 1.2e-18 67.0 18.7 8.7e-08 32.4 0.0 9.7 9 1 1 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.1 CDO70451.1 - 1.2e-17 63.9 9.7 0.00011 22.4 0.0 8.1 2 1 8 10 10 10 8 HEAT repeats IBN_N PF03810.14 CDO70451.1 - 6.1e-11 42.0 4.7 7.4e-11 41.8 0.0 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 CDO70451.1 - 1.4e-09 37.3 9.6 0.0031 17.2 0.0 7.4 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 CDO70451.1 - 0.00024 19.5 4.4 0.39 8.9 0.0 3.4 2 2 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 CDO70451.1 - 0.011 15.0 0.7 8.2 5.7 0.1 4.5 3 2 1 4 4 4 0 CLASP N terminal FPL PF09758.4 CDO70451.1 - 0.039 13.7 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein RIX1 PF08167.7 CDO70451.1 - 0.093 12.3 2.4 15 5.2 0.0 4.3 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis TIP120 PF08623.5 CDO70451.1 - 0.11 12.0 0.2 2.7 7.5 0.0 3.0 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) PSD4 PF07631.6 CDO70452.1 - 0.056 13.8 0.1 0.11 12.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) DUF4203 PF13886.1 CDO70453.1 - 0.22 10.9 8.0 0.25 10.8 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) MU117 PF15474.1 CDO70454.1 - 2e-12 47.4 9.9 2.3e-12 47.1 6.9 1.1 1 0 0 1 1 1 1 Meiotically up-regulated gene family Albumin_I PF08027.6 CDO70454.1 - 0.17 11.6 3.0 2.1 8.1 0.2 2.2 2 1 0 2 2 2 0 Albumin I Fer2 PF00111.22 CDO70454.1 - 0.85 9.4 4.2 0.56 9.9 0.9 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain MIF4G PF02854.14 CDO70455.1 - 3.5e-51 173.6 0.3 4.9e-28 97.9 0.0 3.6 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 CDO70455.1 - 9.6e-27 93.8 9.6 9.6e-27 93.8 6.7 3.0 3 0 0 3 3 3 1 Up-frameshift suppressor 2 RED_C PF07807.6 CDO70455.1 - 0.032 14.4 3.2 0.094 12.9 2.2 1.8 1 0 0 1 1 1 0 RED-like protein C-terminal region DUF3810 PF12725.2 CDO70455.1 - 0.98 8.2 2.1 3 6.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) Ferritin PF00210.19 CDO70456.1 - 0.089 12.5 0.6 13 5.5 0.1 2.6 1 1 1 3 3 3 0 Ferritin-like domain CDK2AP PF09806.4 CDO70456.1 - 0.34 11.1 6.3 0.69 10.1 4.2 1.5 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Herpes_UL36 PF03586.8 CDO70456.1 - 0.85 8.6 7.1 12 4.9 4.6 2.1 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein Hemerythrin PF01814.18 CDO70456.1 - 7.7 6.6 8.1 6.3 6.9 3.0 2.5 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain UBN2_2 PF14227.1 CDO70457.1 - 2.1e-09 36.9 0.0 4.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO70457.1 - 8.1e-09 35.2 1.7 3.6e-08 33.0 0.5 2.4 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO70457.1 - 1.3e-08 34.0 0.5 2.6e-08 33.0 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 CDO70457.1 - 7.6e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DDHD PF02862.12 CDO70457.1 - 0.92 9.2 4.1 1.6 8.4 2.8 1.3 1 0 0 1 1 1 0 DDHD domain HSBP1 PF06825.7 CDO70459.1 - 0.0028 17.1 1.8 0.49 10.0 0.2 2.9 3 0 0 3 3 3 2 Heat shock factor binding protein 1 Phage_GPO PF05929.6 CDO70459.1 - 0.0088 15.3 0.5 0.014 14.6 0.3 1.3 1 1 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase Dynamitin PF04912.9 CDO70459.1 - 0.012 14.4 1.1 0.025 13.3 0.7 1.8 1 1 0 1 1 1 0 Dynamitin Enkurin PF13864.1 CDO70459.1 - 1.2 9.4 4.8 0.96 9.6 0.4 2.2 1 1 1 2 2 2 0 Calmodulin-binding Pkinase PF00069.20 CDO70461.1 - 4.6e-69 232.4 0.0 5.5e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70461.1 - 2.1e-27 95.8 0.0 3.1e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO70461.1 - 9.2e-06 24.8 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CDO70461.1 - 0.00079 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CDO70461.1 - 0.0038 16.3 0.3 0.0094 15.0 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDO70461.1 - 0.0044 16.7 0.3 0.27 10.9 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family TcdB_toxin_midN PF12256.3 CDO70461.1 - 0.058 12.8 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region YukC PF10140.4 CDO70461.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC HET PF06985.6 CDO70462.1 - 5.7e-18 65.4 4.4 2.1e-14 53.8 0.1 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Acetyltransf_1 PF00583.19 CDO70463.1 - 3.8e-16 58.8 0.0 5.2e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDO70463.1 - 3.6e-07 30.2 0.0 6.3e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDO70463.1 - 1.4e-05 25.1 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CDO70463.1 - 0.00071 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 CDO70463.1 - 0.0078 16.1 0.0 0.012 15.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO70463.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.1 CDO70463.1 - 0.023 14.8 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CDO70463.1 - 0.048 13.6 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAC PF01849.13 CDO70464.1 - 2.1e-21 75.1 0.0 3.6e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 NAC domain Astro_capsid_p PF12226.3 CDO70464.1 - 0.18 11.0 0.6 0.31 10.2 0.2 1.4 2 0 0 2 2 2 0 Turkey astrovirus capsid protein WD40 PF00400.27 CDO70465.1 - 5.5e-38 127.5 15.7 1e-06 28.3 2.2 9.4 10 1 0 10 10 10 7 WD domain, G-beta repeat CPSF_A PF03178.10 CDO70465.1 - 9e-05 21.7 0.0 0.16 11.0 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region Mad3_BUB1_I PF08311.7 CDO70466.1 - 1.1e-28 99.5 0.1 1.6e-28 98.9 0.1 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 ECH PF00378.15 CDO70466.1 - 0.0046 16.1 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pro-kuma_activ PF09286.6 CDO70467.1 - 6e-40 136.5 0.3 4.2e-39 133.8 0.1 2.3 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO70467.1 - 2.8e-08 33.2 0.1 2.8e-08 33.2 0.1 1.9 1 1 1 2 2 2 1 Subtilase family Pro-kuma_activ PF09286.6 CDO70468.1 - 9.6e-33 113.2 0.1 7.1e-32 110.4 0.1 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Glyco_hydro_47 PF01532.15 CDO70470.1 - 3.2e-102 342.5 0.0 4.3e-102 342.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 zf-CSL PF05207.8 CDO70471.1 - 0.0089 15.5 0.3 0.89 9.1 0.1 2.7 2 0 0 2 2 2 2 CSL zinc finger FtsL PF04999.8 CDO70471.1 - 0.11 12.2 2.1 0.17 11.6 0.5 1.9 2 0 0 2 2 2 0 Cell division protein FtsL Ribophorin_II PF05817.9 CDO70472.1 - 1.5e-30 106.0 0.0 2e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF4232 PF14016.1 CDO70472.1 - 0.074 12.7 0.1 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) PCI PF01399.22 CDO70475.1 - 2.2e-21 76.1 0.0 6.3e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.6 CDO70475.1 - 1.4e-10 41.4 9.7 3.2e-06 27.4 0.0 3.7 4 0 0 4 4 4 2 Proteasome regulatory subunit C-terminal OKR_DC_1_C PF03711.10 CDO70475.1 - 0.0034 17.4 1.2 0.032 14.2 0.0 2.6 3 0 0 3 3 3 1 Orn/Lys/Arg decarboxylase, C-terminal domain TPR_2 PF07719.12 CDO70475.1 - 0.0054 16.5 1.9 0.16 11.9 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CDO70475.1 - 0.015 14.8 0.8 0.015 14.8 0.5 2.2 2 0 0 2 2 2 0 TPR repeat PCI_Csn8 PF10075.4 CDO70475.1 - 0.024 14.3 0.1 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 CDO70475.1 - 0.051 13.5 9.1 0.53 10.2 0.7 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat FdhE PF04216.7 CDO70475.1 - 0.64 9.6 6.0 1.7 8.2 0.2 2.4 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation TPR_16 PF13432.1 CDO70475.1 - 5.1 7.8 12.0 1.7 9.4 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat WW PF00397.21 CDO70476.1 - 0.00058 19.6 2.4 0.014 15.2 0.1 2.7 2 0 0 2 2 2 2 WW domain Cation_efflux PF01545.16 CDO70476.1 - 0.02 14.0 0.2 0.056 12.5 0.1 1.7 1 1 1 2 2 2 0 Cation efflux family Peptidase_C14 PF00656.17 CDO70477.1 - 4.3e-38 131.4 0.0 5.5e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 CDO70477.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.4 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Afi1 PF07792.7 CDO70479.1 - 4.4e-35 120.8 0.0 7.8e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 CDO70479.1 - 4.7e-32 110.0 0.0 7.9e-32 109.3 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CDO70479.1 - 3.3e-05 22.5 0.0 0.0012 17.3 0.0 2.8 3 1 0 4 4 4 1 Transport protein Avl9 Coatomer_WDAD PF04053.9 CDO70481.1 - 3.8e-142 474.2 0.0 1.2e-141 472.4 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 CDO70481.1 - 3.8e-102 341.9 0.0 5.6e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CDO70481.1 - 2.8e-55 182.3 10.3 1.8e-10 40.2 0.0 8.2 9 0 0 9 9 9 5 WD domain, G-beta repeat TPR_16 PF13432.1 CDO70481.1 - 0.0019 18.7 2.2 6.5 7.5 0.4 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Nup160 PF11715.3 CDO70481.1 - 0.0098 14.0 5.4 0.052 11.6 0.0 3.2 1 1 3 4 4 4 1 Nucleoporin Nup120/160 TPR_2 PF07719.12 CDO70481.1 - 0.056 13.3 0.4 17 5.6 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.15 CDO70481.1 - 0.066 12.8 0.1 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_14 PF13428.1 CDO70481.1 - 0.47 11.2 7.2 3.9 8.3 0.4 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat XPG_I PF00867.13 CDO70482.1 - 1.5e-15 57.0 0.0 2.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CDO70482.1 - 0.0023 18.1 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold LIM PF00412.17 CDO70483.1 - 9.4e-16 57.6 14.8 3.2e-11 43.1 5.2 3.1 3 0 0 3 3 3 3 LIM domain p450 PF00067.17 CDO70484.1 - 5.9e-50 170.1 0.0 1.3e-49 168.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 COesterase PF00135.23 CDO70485.1 - 6.9e-88 295.6 2.5 2.2e-87 293.9 1.7 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CDO70485.1 - 1e-09 38.2 0.3 4.6e-09 36.1 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDO70485.1 - 9.1e-05 21.7 0.5 0.00016 20.9 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDO70485.1 - 0.0051 16.5 0.3 0.0091 15.7 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2235 PF09994.4 CDO70485.1 - 0.038 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) FoP_duplication PF13865.1 CDO70486.1 - 1.5e-06 28.5 0.5 3.1e-06 27.5 0.3 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 CDO70486.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO70486.1 - 0.00019 20.9 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO70486.1 - 0.017 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PMG PF05287.7 CDO70487.1 - 0.18 11.5 9.0 0.16 11.7 2.1 2.1 2 0 0 2 2 2 0 PMG protein HlyIII PF03006.15 CDO70488.1 - 2.8e-43 147.8 12.9 3.6e-43 147.5 8.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related p450 PF00067.17 CDO70489.1 - 1.7e-22 79.6 0.0 4.4e-14 51.8 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 RVT_1 PF00078.22 CDO70490.1 - 9e-08 31.7 0.0 3.8e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CDO70490.1 - 0.0007 19.1 0.1 0.0021 17.6 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Cofilin_ADF PF00241.15 CDO70491.1 - 1.8e-19 69.8 0.2 2.1e-19 69.6 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein IQ-like PF15157.1 CDO70491.1 - 0.11 12.6 0.1 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 IQ-like Sec20 PF03908.8 CDO70492.1 - 7.6e-16 57.5 1.5 7.6e-16 57.5 1.1 2.3 3 1 1 4 4 4 1 Sec20 Baculo_11_kDa PF06143.6 CDO70492.1 - 0.045 13.1 0.1 0.14 11.5 0.1 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family Syntaxin-6_N PF09177.6 CDO70492.1 - 3.6 8.0 11.9 1.8 9.0 3.1 3.2 1 1 1 3 3 3 0 Syntaxin 6, N-terminal Neugrin PF06413.6 CDO70493.1 - 7.7e-12 45.5 2.3 1.3e-11 44.7 1.6 1.5 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 CDO70493.1 - 1.2e-06 28.5 10.1 2.8e-06 27.4 7.0 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 MarR_2 PF12802.2 CDO70493.1 - 0.0062 16.1 0.1 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_Tnp_ISL3 PF13542.1 CDO70493.1 - 0.054 12.6 3.9 0.81 8.9 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 BTB PF00651.26 CDO70494.1 - 8.8e-06 25.6 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain FYVE PF01363.16 CDO70495.1 - 2e-08 33.9 5.1 5.1e-08 32.7 3.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 CDO70495.1 - 4.8e-05 23.2 3.5 4.8e-05 23.2 2.4 2.2 3 0 0 3 3 2 1 FYVE-type zinc finger Armet PF10208.4 CDO70495.1 - 0.00044 19.9 0.2 0.65 9.6 0.0 2.3 2 0 0 2 2 2 2 Degradation arginine-rich protein for mis-folding SAP PF02037.22 CDO70495.1 - 0.0035 16.8 0.2 0.072 12.6 0.0 2.5 2 1 0 2 2 2 1 SAP domain DUF2254 PF10011.4 CDO70495.1 - 0.0041 15.6 0.9 0.46 8.9 0.3 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2254) zf-C3HC4_3 PF13920.1 CDO70495.1 - 0.012 15.2 0.1 0.012 15.2 0.1 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rho_N PF07498.7 CDO70495.1 - 0.019 14.6 0.3 0.038 13.7 0.2 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain DUF572 PF04502.8 CDO70495.1 - 0.14 11.3 7.8 0.022 14.0 2.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4518 PF15008.1 CDO70495.1 - 0.56 9.1 1.7 2.5 7.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) C1_1 PF00130.17 CDO70495.1 - 0.61 9.8 8.0 0.15 11.8 2.9 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 CDO70495.1 - 1.3 9.1 12.3 0.9 9.6 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Menin PF05053.8 CDO70495.1 - 1.7 6.7 8.3 2.5 6.1 5.8 1.2 1 0 0 1 1 1 0 Menin UPF0547 PF10571.4 CDO70495.1 - 2.5 7.8 7.0 0.31 10.7 0.3 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.5 CDO70495.1 - 3.7 7.5 9.7 3.4 7.6 1.8 2.8 1 1 1 2 2 2 0 Zinc ribbon domain Chromo PF00385.19 CDO70496.1 - 1.8e-08 33.8 0.7 3.1e-08 33.1 0.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 CDO70496.1 - 4.6e-05 23.0 0.1 9e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 PHD-finger MbeD_MobD PF04899.7 CDO70496.1 - 0.09 12.6 0.1 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 MbeD/MobD like PXA PF02194.10 CDO70496.1 - 0.23 10.9 1.2 0.4 10.2 0.9 1.3 1 0 0 1 1 1 0 PXA domain FMO-like PF00743.14 CDO70497.1 - 1.1e-44 152.6 0.0 3.1e-33 114.7 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CDO70497.1 - 6.6e-18 65.5 0.0 1.5e-17 64.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO70497.1 - 1.4e-08 34.6 0.1 4e-05 23.4 0.0 3.2 3 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 CDO70497.1 - 7.6e-07 28.3 0.0 0.00028 19.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CDO70497.1 - 2.1e-05 24.4 0.0 0.0014 18.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CDO70497.1 - 2.3e-05 24.7 1.1 0.0028 18.0 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDO70497.1 - 6.6e-05 22.8 0.0 0.0011 18.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CDO70497.1 - 0.00079 18.4 0.2 1.7 7.4 0.0 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase DJ-1_PfpI PF01965.19 CDO70497.1 - 0.0041 16.5 0.0 0.096 12.1 0.0 2.7 3 0 0 3 3 3 1 DJ-1/PfpI family Amino_oxidase PF01593.19 CDO70497.1 - 0.065 12.2 0.0 9.5 5.1 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase PipA PF07108.6 CDO70497.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 PipA protein Tannase PF07519.6 CDO70498.1 - 7.1e-75 252.5 0.2 5.2e-74 249.6 0.1 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase p450 PF00067.17 CDO70499.1 - 1.1e-43 149.4 0.0 2.2e-24 85.8 0.0 3.1 3 0 0 3 3 3 3 Cytochrome P450 DUF3481 PF11980.3 CDO70500.1 - 0.0076 16.0 0.0 0.021 14.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3481) EphA2_TM PF14575.1 CDO70500.1 - 0.026 14.9 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 CDO70500.1 - 0.25 11.0 0.9 0.51 10.0 0.6 1.4 1 0 0 1 1 1 0 Syndecan domain Gly-zipper_Omp PF13488.1 CDO70500.1 - 0.61 9.7 12.4 2.1 8.0 8.6 1.9 1 0 0 1 1 1 0 Glycine zipper CD99L2 PF12301.3 CDO70500.1 - 0.67 9.6 4.8 1.5 8.4 0.4 2.3 2 0 0 2 2 2 0 CD99 antigen like protein 2 DUF347 PF03988.7 CDO70500.1 - 5 7.0 6.7 4.6 7.2 0.3 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) p450 PF00067.17 CDO70501.1 - 1.3e-47 162.3 1.5 3.3e-22 78.6 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 FMO-like PF00743.14 CDO70501.1 - 6.1e-39 133.6 0.0 3.5e-28 98.0 0.0 2.7 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CDO70501.1 - 8.9e-16 58.5 0.0 1.8e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CDO70501.1 - 1.8e-07 30.4 0.0 4.3e-06 25.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CDO70501.1 - 2.1e-06 27.7 0.0 1.7e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO70501.1 - 2.8e-05 23.9 2.8 0.0093 15.7 0.3 4.5 3 2 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CDO70501.1 - 5.4e-05 23.1 0.2 0.00048 20.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CDO70501.1 - 0.022 13.8 0.0 0.35 9.9 0.0 2.3 2 0 0 2 2 2 0 Thi4 family DUF221 PF02714.10 CDO70502.1 - 6.2e-105 350.6 21.6 9.5e-105 350.0 14.9 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CDO70502.1 - 1.1e-36 125.7 5.3 1.1e-36 125.7 3.6 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CDO70502.1 - 2.1e-15 56.9 1.1 5.5e-15 55.6 0.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 CDO70502.1 - 4e-14 52.2 0.1 1.2e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein TarH PF02203.10 CDO70502.1 - 0.36 10.6 3.7 6.2 6.6 0.2 2.6 2 0 0 2 2 2 0 Tar ligand binding domain homologue F-box-like PF12937.2 CDO70503.1 - 9e-09 34.9 0.2 3.1e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO70503.1 - 0.00088 18.8 0.0 0.0036 16.9 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO70504.1 - 9.6e-09 34.8 0.2 1.5e-08 34.1 0.1 1.4 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 CDO70504.1 - 0.00061 19.4 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 CDO70504.1 - 0.00094 18.7 0.5 0.0018 17.8 0.4 1.5 1 1 0 1 1 1 1 F-box domain TPR_9 PF13371.1 CDO70504.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat ADH_zinc_N PF00107.21 CDO70505.1 - 3.7e-29 100.9 2.1 6.7e-29 100.0 1.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO70505.1 - 2.3e-28 98.1 0.9 4e-28 97.3 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CDO70505.1 - 0.00073 20.4 0.4 0.0013 19.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SH2_2 PF14633.1 CDO70505.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 SH2 domain p450 PF00067.17 CDO70506.1 - 1.2e-53 182.3 0.0 1.4e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Spindle_Spc25 PF08234.7 CDO70507.1 - 7.4e-09 35.4 0.1 2.4e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4200 PF13863.1 CDO70507.1 - 0.00056 19.8 12.4 0.00056 19.8 8.6 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) IncA PF04156.9 CDO70507.1 - 0.012 15.1 8.6 0.015 14.8 5.9 1.1 1 0 0 1 1 1 0 IncA protein DUF1092 PF06485.6 CDO70507.1 - 0.014 14.3 2.5 0.018 14.0 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) ERM PF00769.14 CDO70507.1 - 0.097 12.1 13.1 0.12 11.8 9.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family MecA_N PF05223.6 CDO70507.1 - 0.17 11.9 2.5 0.22 11.5 1.8 1.3 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain APG6 PF04111.7 CDO70507.1 - 0.19 10.7 10.7 0.23 10.4 7.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 CDO70507.1 - 0.37 9.1 7.2 0.46 8.8 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CMV_1a PF12467.3 CDO70507.1 - 0.44 10.8 5.8 0.66 10.3 4.0 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family THOC7 PF05615.8 CDO70507.1 - 0.67 10.2 12.6 1.5 9.0 8.6 1.5 1 1 1 2 2 2 0 Tho complex subunit 7 Syntaxin PF00804.20 CDO70507.1 - 1.4 9.0 9.5 2.6 8.2 6.2 1.7 1 1 0 1 1 1 0 Syntaxin AAA_23 PF13476.1 CDO70507.1 - 2 8.6 6.1 2.8 8.2 4.2 1.2 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 CDO70507.1 - 3.9 7.0 13.4 5.3 6.6 8.9 1.4 1 1 0 1 1 1 0 Mnd1 family AATase PF07247.7 CDO70508.1 - 9.9e-26 90.3 0.0 3.5e-24 85.2 0.0 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CDO70508.1 - 3e-08 32.8 0.0 8.7e-08 31.3 0.0 1.6 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.11 CDO70508.1 - 0.0031 17.1 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Fzo_mitofusin PF04799.8 CDO70508.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region PAS_5 PF07310.8 CDO70508.1 - 0.02 14.4 0.1 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 PAS domain p450 PF00067.17 CDO70510.1 - 1.1e-12 47.2 0.0 1.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CDO70511.1 - 2.7e-30 105.3 0.0 5.4e-30 104.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF1770 PF08589.5 CDO70512.1 - 2.3e-06 28.1 1.6 5.7e-06 26.8 1.1 1.8 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PIG-L PF02585.12 CDO70513.1 - 1.1e-12 48.5 0.0 1.4e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF3455 PF11937.3 CDO70514.1 - 1.9e-18 67.0 0.0 3.3e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) DUF3415 PF11895.3 CDO70515.1 - 1.2e-35 121.1 2.2 3e-35 119.9 1.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 CDO70515.1 - 4.9e-30 104.7 0.0 8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF3143 PF11341.3 CDO70515.1 - 0.056 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) HET PF06985.6 CDO70517.1 - 1.3e-15 57.8 2.4 5.1e-06 26.6 0.5 4.5 2 2 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.8 CDO70519.1 - 3.1e-14 53.0 1.0 6.9e-08 32.3 0.4 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1295 PF06966.7 CDO70520.1 - 0.00015 21.1 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) F-box-like PF12937.2 CDO70521.1 - 3.2e-08 33.1 0.3 3.2e-08 33.1 0.2 2.3 2 0 0 2 2 2 1 F-box-like Laminin_II PF06009.7 CDO70521.1 - 0.032 13.9 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Laminin Domain II EzrA PF06160.7 CDO70521.1 - 0.036 12.2 0.1 0.049 11.8 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA F-box PF00646.28 CDO70521.1 - 4.3 7.0 7.9 2.8 7.6 1.1 3.5 2 1 0 2 2 2 0 F-box domain p450 PF00067.17 CDO70522.1 - 7.5e-52 176.3 0.0 2.8e-50 171.2 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 SWIRM PF04433.12 CDO70524.1 - 8.1e-36 122.0 0.1 1.8e-35 120.9 0.0 1.6 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 CDO70524.1 - 8.4e-10 38.6 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CDO70524.1 - 1.3e-09 37.9 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 CDO70524.1 - 1.7e-09 37.0 2.0 3.2e-09 36.1 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Glyco_hydro_61 PF03443.9 CDO70526.1 - 1.5e-31 109.8 0.0 1.9e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 CDO70527.1 - 1.1e-05 25.4 0.0 1.2e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.20 CDO70528.1 - 7.4e-67 225.2 0.0 1e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70528.1 - 1.4e-31 109.5 0.0 2.3e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO70528.1 - 0.0002 21.1 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CDO70528.1 - 0.51 9.0 0.1 0.76 8.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Syntaxin-6_N PF09177.6 CDO70529.1 - 8.3e-22 77.4 4.1 2.6e-21 75.8 0.2 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 CDO70529.1 - 9.6e-13 47.6 3.1 9.6e-13 47.6 2.1 2.0 3 0 0 3 3 3 1 SNARE domain DUF3584 PF12128.3 CDO70529.1 - 0.0013 16.1 1.9 0.0018 15.7 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PspA_IM30 PF04012.7 CDO70529.1 - 0.0024 17.2 6.8 0.003 16.9 0.5 2.6 3 0 0 3 3 3 1 PspA/IM30 family Spectrin PF00435.16 CDO70529.1 - 0.028 14.6 4.2 0.06 13.6 0.1 2.5 2 2 0 2 2 2 0 Spectrin repeat FlaC_arch PF05377.6 CDO70529.1 - 0.035 13.9 4.3 1.7 8.5 0.2 3.5 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 CDO70529.1 - 0.04 13.7 2.9 6.4 6.6 0.2 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 CDO70529.1 - 0.13 12.6 0.4 0.13 12.6 0.3 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TBPIP PF07106.8 CDO70529.1 - 0.14 11.7 4.8 2 7.9 0.1 2.4 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF948 PF06103.6 CDO70529.1 - 0.15 11.9 1.5 6.7 6.6 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF641 PF04859.7 CDO70529.1 - 0.26 11.0 8.1 1 9.1 0.1 3.3 2 2 2 4 4 4 0 Plant protein of unknown function (DUF641) IncA PF04156.9 CDO70529.1 - 0.3 10.6 8.1 0.37 10.3 0.5 2.2 1 1 0 2 2 2 0 IncA protein Snapin_Pallidin PF14712.1 CDO70529.1 - 0.56 10.5 3.4 20 5.5 0.1 2.5 2 1 0 2 2 2 0 Snapin/Pallidin EzrA PF06160.7 CDO70529.1 - 0.59 8.2 4.3 2.3 6.2 0.6 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Laminin_I PF06008.9 CDO70529.1 - 0.86 8.8 10.5 0.81 8.9 1.3 2.3 2 1 0 2 2 2 0 Laminin Domain I ATG16 PF08614.6 CDO70529.1 - 1 9.1 6.7 4.1 7.1 4.0 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4633 PF15464.1 CDO70529.1 - 1.2 9.0 4.4 0.8 9.5 1.2 2.0 2 1 1 3 3 2 0 Domain of unknown function (DUF4633) Filament PF00038.16 CDO70529.1 - 1.2 8.5 7.5 6.5 6.1 1.0 2.2 2 0 0 2 2 2 0 Intermediate filament protein Vir_act_alpha_C PF10400.4 CDO70529.1 - 2.5 8.5 8.2 1.6 9.1 0.1 3.2 3 1 1 4 4 3 0 Virulence activator alpha C-term APG6 PF04111.7 CDO70529.1 - 3 6.8 5.0 6.7 5.6 0.2 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 HisKA_3 PF07730.8 CDO70529.1 - 5.2 7.4 10.6 2.6 8.4 0.8 3.5 3 1 0 3 3 3 0 Histidine kinase zf-C3HC4_3 PF13920.1 CDO70530.1 - 3.6e-11 42.5 4.0 1.9e-09 37.0 0.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO70530.1 - 5e-06 26.4 5.0 7.2e-06 25.9 1.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO70530.1 - 0.00024 20.6 1.8 0.00088 18.8 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO70530.1 - 0.00034 20.3 3.8 0.0044 16.8 0.8 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CDO70530.1 - 0.0079 15.9 2.6 0.078 12.7 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 CDO70530.1 - 2.9 7.5 6.1 0.58 9.7 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ribosomal_L18e PF00828.14 CDO70531.1 - 3.4e-36 124.4 0.1 4.6e-36 124.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RNA_pol_L_2 PF13656.1 CDO70532.1 - 1.4e-25 88.4 0.0 2e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CDO70532.1 - 2.5e-14 52.1 0.0 3.3e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.6 CDO70532.1 - 0.0089 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Rio2, N-terminal TUG-UBL1 PF11470.3 CDO70532.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 GLUT4 regulating protein TUG RVT_1 PF00078.22 CDO70533.1 - 2.6e-19 69.4 0.0 7.7e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO70533.1 - 2.4e-13 50.5 0.0 5.6e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 CDO70533.1 - 1.4e-09 37.6 0.0 3e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CDO70533.1 - 0.0011 19.2 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zf-CCHC_6 PF15288.1 CDO70533.1 - 0.016 14.9 1.3 0.064 12.9 1.0 2.0 2 0 0 2 2 2 0 Zinc knuckle ERM PF00769.14 CDO70533.1 - 0.08 12.4 3.0 0.16 11.4 2.1 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Laminin_II PF06009.7 CDO70533.1 - 0.16 11.7 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF3328 PF11807.3 CDO70535.1 - 1.4e-14 54.3 0.8 1.7e-14 54.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.4 CDO70536.1 - 1.6e-08 34.4 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.3 CDO70537.1 - 3.3e-15 56.3 4.2 1.6e-14 54.1 2.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1917 PF08939.5 CDO70538.1 - 9.8e-25 87.6 0.1 9.8e-25 87.6 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) GAGA_bind PF06217.7 CDO70541.1 - 0.12 12.2 17.2 0.18 11.7 11.9 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4305 PF14146.1 CDO70542.1 - 0.08 12.6 3.7 0.15 11.8 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4305) p450 PF00067.17 CDO70543.1 - 8.8e-33 113.5 0.3 4.9e-17 61.6 0.0 3.9 3 1 0 3 3 3 3 Cytochrome P450 MotB_plug PF13677.1 CDO70543.1 - 0.26 10.6 0.1 0.26 10.6 0.1 1.7 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB p450 PF00067.17 CDO70546.1 - 2.5e-59 201.0 0.0 2.6e-58 197.6 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 NfeD PF01957.13 CDO70547.1 - 9.5 6.3 9.9 0.33 11.0 0.3 2.6 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding MFS_1 PF07690.11 CDO70548.1 - 1.1e-07 30.9 25.3 5e-07 28.7 15.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Phage_CII PF05269.6 CDO70548.1 - 0.12 12.3 0.0 5 7.1 0.0 2.3 1 1 1 2 2 2 0 Bacteriophage CII protein MFS_1 PF07690.11 CDO70549.1 - 7.4e-25 87.4 36.7 1e-24 86.9 25.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 CDO70549.1 - 0.00056 19.8 0.5 0.00056 19.8 0.3 4.1 4 1 1 5 5 5 1 Protein of unknown function (DUF1228) Pex2_Pex12 PF04757.9 CDO70549.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region ELYS PF13934.1 CDO70550.1 - 2.7e-51 174.4 0.1 3.8e-51 173.9 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly PBP1_TM PF14812.1 CDO70550.1 - 6.7 7.0 8.8 5.2 7.4 2.2 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 CDO70550.1 - 9.5 5.7 7.9 5.1 6.5 1.7 2.2 2 0 0 2 2 2 0 Nucleoplasmin HMG_box PF00505.14 CDO70551.1 - 0.034 14.3 0.1 0.075 13.3 0.1 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box EB1_binding PF05937.6 CDO70551.1 - 0.064 13.6 1.2 0.13 12.6 0.8 1.6 1 0 0 1 1 1 0 EB-1 Binding Domain p450 PF00067.17 CDO70552.1 - 7.1e-48 163.2 0.0 1.3e-38 132.6 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Ribosomal_S5_C PF03719.10 CDO70553.1 - 1.5e-15 56.2 0.2 5.2e-15 54.4 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 CDO70553.1 - 2.7e-13 49.4 1.1 4.1e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain PITH PF06201.8 CDO70554.1 - 8.8e-18 64.5 0.0 1.1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain Pkinase PF00069.20 CDO70555.1 - 1.2e-52 178.6 0.0 1.7e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70555.1 - 7.4e-29 100.5 0.0 1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CDO70555.1 - 0.00024 20.0 1.7 0.00042 19.2 0.1 1.8 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CDO70555.1 - 0.00025 20.1 0.0 0.01 14.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CDO70555.1 - 0.02 14.6 1.6 0.021 14.5 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Asp PF00026.18 CDO70556.1 - 7.6e-40 137.0 0.3 1.8e-39 135.8 0.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO70556.1 - 0.00043 20.2 0.1 0.0052 16.7 0.1 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CDO70556.1 - 0.016 14.7 0.1 0.41 10.1 0.0 2.8 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CDO70556.1 - 0.062 13.8 1.5 9 6.8 0.0 3.4 2 1 0 2 2 2 0 Aspartyl protease ATP-synt_10 PF05176.9 CDO70557.1 - 5.6e-69 232.2 0.0 6.8e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein TPT PF03151.11 CDO70559.1 - 4.7e-24 84.7 10.3 4.7e-24 84.7 7.2 2.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CDO70559.1 - 0.00033 19.6 14.5 0.0023 16.9 3.7 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 CDO70559.1 - 0.0017 18.3 28.5 0.0046 17.0 5.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CDO70559.1 - 0.0079 16.3 5.8 0.0079 16.3 4.0 2.8 2 1 0 2 2 2 2 Multidrug resistance efflux transporter DUF1118 PF06549.7 CDO70559.1 - 0.22 11.6 6.0 0.25 11.4 2.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1118) DUF914 PF06027.7 CDO70559.1 - 1.2 7.8 14.4 17 4.1 10.0 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) LSM PF01423.17 CDO70562.1 - 1.7e-09 37.0 0.1 2.5e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain Glyco_hydro_28 PF00295.12 CDO70563.1 - 4.1e-48 164.0 13.5 5.3e-48 163.6 9.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RmlD_sub_bind PF04321.12 CDO70566.1 - 5.7e-40 137.0 0.0 1.8e-31 109.0 0.0 2.0 1 1 1 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.16 CDO70566.1 - 1e-16 61.1 0.0 6.1e-08 32.3 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO70566.1 - 0.00074 19.5 0.0 0.0017 18.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CDO70566.1 - 0.0015 17.5 0.1 0.021 13.7 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein DapB_N PF01113.15 CDO70566.1 - 0.024 14.5 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RTC4 PF14474.1 CDO70567.1 - 4e-10 39.6 0.0 9e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain SDA1 PF05285.7 CDO70567.1 - 0.019 14.2 8.0 0.092 12.0 0.5 2.4 2 0 0 2 2 2 0 SDA1 Sigma70_ner PF04546.8 CDO70567.1 - 0.093 12.3 2.0 0.23 11.0 1.4 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Transposase_21 PF02992.9 CDO70568.1 - 2.3e-22 79.2 0.0 4.3e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF2167 PF09935.4 CDO70568.1 - 0.16 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) NUDIX PF00293.23 CDO70571.1 - 2.4e-14 53.1 0.1 3.1e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain UPF0150 PF03681.10 CDO70571.1 - 0.0081 15.7 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0150) Ldh_1_N PF00056.18 CDO70572.1 - 4.2e-46 156.2 0.1 6.4e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CDO70572.1 - 2.6e-38 131.5 0.0 3.4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CDO70572.1 - 0.0001 21.1 0.0 0.00023 19.9 0.0 1.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 CDO70572.1 - 0.0053 16.0 0.1 0.19 11.0 0.0 2.4 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase NAD_binding_10 PF13460.1 CDO70572.1 - 0.083 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 CDO70572.1 - 0.63 9.1 4.4 2.6 7.1 0.1 3.2 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DEAD PF00270.24 CDO70573.1 - 9.5e-42 142.3 0.0 7.1e-41 139.5 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO70573.1 - 1.1e-22 79.6 0.0 3.6e-22 78.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO70573.1 - 0.0038 17.0 0.1 0.1 12.3 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CDO70573.1 - 0.0049 16.8 1.9 0.0083 16.0 0.0 2.3 3 0 0 3 3 3 1 Helicase C-terminal domain DUF2608 PF11019.3 CDO70573.1 - 0.011 14.7 0.1 0.026 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Ycf1 PF05758.7 CDO70573.1 - 0.036 11.8 4.9 0.048 11.3 3.4 1.1 1 0 0 1 1 1 0 Ycf1 DUF1253 PF06862.7 CDO70573.1 - 0.07 11.5 0.0 0.07 11.5 0.0 2.7 3 1 0 4 4 4 0 Protein of unknown function (DUF1253) SecA_DEAD PF07517.9 CDO70573.1 - 0.16 11.2 1.6 0.39 9.9 1.1 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain CMS1 PF14617.1 CDO70573.1 - 0.17 10.9 8.6 0.6 9.1 0.0 2.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit zf-CCHC PF00098.18 CDO70573.1 - 0.54 10.2 1.6 0.93 9.5 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4207 PF13904.1 CDO70573.1 - 1.3 8.3 17.9 1.9 7.7 12.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) RR_TM4-6 PF06459.7 CDO70573.1 - 3.5 7.4 12.9 6 6.6 8.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GalP_UDP_transf PF01087.17 CDO70574.1 - 6.1e-66 221.9 0.1 1.4e-65 220.7 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CDO70574.1 - 1.6e-47 161.1 0.0 3.6e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 CDO70574.1 - 0.12 12.9 0.6 2.2 8.8 0.0 2.8 3 0 0 3 3 3 0 HIT domain DcpS_C PF11969.3 CDO70574.1 - 1.5 9.0 4.3 7.6 6.7 1.8 2.8 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding SDA1 PF05285.7 CDO70575.1 - 2.5e-86 289.8 35.5 4.2e-86 289.1 18.2 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 CDO70575.1 - 2.1e-23 82.3 0.0 1.1e-22 80.0 0.0 2.2 2 0 0 2 2 2 1 NUC130/3NT domain Nop14 PF04147.7 CDO70575.1 - 0.034 12.0 19.1 2.7 5.8 0.0 2.9 3 0 0 3 3 3 0 Nop14-like family EBP PF05241.7 CDO70575.1 - 0.21 10.5 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Emopamil binding protein Sigma70_ner PF04546.8 CDO70576.1 - 0.048 13.2 12.7 0.077 12.6 8.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3650 PF12368.3 CDO70576.1 - 0.095 12.2 0.2 0.19 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) CAML PF14963.1 CDO70576.1 - 0.18 11.1 8.9 0.27 10.5 6.1 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand YbgS PF13985.1 CDO70576.1 - 0.51 10.2 4.6 1.2 9.0 3.2 1.7 1 1 0 1 1 1 0 YbgS-like protein DUF4061 PF13270.1 CDO70576.1 - 0.94 9.6 6.4 2.3 8.3 4.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) Atg14 PF10186.4 CDO70576.1 - 2.9 6.7 12.2 3.8 6.3 8.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CDO70576.1 - 6.1 6.3 7.9 8.2 5.9 5.4 1.2 1 0 0 1 1 1 0 IncA protein PGK PF00162.14 CDO70577.1 - 9.2e-150 498.4 0.0 1.3e-149 498.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoglycerate kinase Sel1 PF08238.7 CDO70577.1 - 1.7e-44 149.2 36.0 9.8e-08 32.3 0.0 8.7 9 0 0 9 9 9 7 Sel1 repeat PITH PF06201.8 CDO70577.1 - 5.5e-33 113.8 0.4 9.2e-33 113.1 0.2 1.3 1 0 0 1 1 1 1 PITH domain JmjC PF02373.17 CDO70577.1 - 2.6e-07 30.8 0.6 2.2e-06 27.9 0.4 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CDO70577.1 - 0.00028 20.4 0.4 0.00068 19.2 0.3 1.6 1 0 0 1 1 1 1 Cupin-like domain TPR_14 PF13428.1 CDO70577.1 - 6.9 7.6 16.8 1 10.1 0.9 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat CN_hydrolase PF00795.17 CDO70578.1 - 4.8e-27 94.5 0.0 7.3e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DnaJ PF00226.26 CDO70578.1 - 1e-23 82.8 1.5 2e-23 81.8 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CDO70578.1 - 1.1e-18 66.9 1.3 8.6e-17 60.8 0.0 3.1 4 0 0 4 4 4 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CDO70578.1 - 2.3e-15 56.3 17.0 4e-15 55.6 11.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Transposase_1 PF01359.13 CDO70578.1 - 0.19 11.5 0.0 0.55 10.0 0.0 1.7 1 0 0 1 1 1 0 Transposase (partial DDE domain) HypA PF01155.14 CDO70578.1 - 0.3 10.7 9.8 0.75 9.5 2.0 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Ras PF00071.17 CDO70579.1 - 2.2e-52 176.7 0.0 2.5e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO70579.1 - 1.8e-16 60.6 0.0 2.5e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO70579.1 - 1.2e-06 27.8 0.0 2.9e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CDO70579.1 - 0.01 15.2 0.0 0.031 13.7 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CDO70579.1 - 0.021 13.9 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CDO70579.1 - 0.14 11.6 0.0 5.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PIG-X PF08320.7 CDO70580.1 - 3.5e-19 68.9 0.2 1.1e-18 67.2 0.1 1.7 1 1 0 1 1 1 1 PIG-X / PBN1 6PF2K PF01591.13 CDO70581.1 - 1.9e-59 200.4 0.1 2.7e-31 108.3 0.0 2.0 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CDO70581.1 - 2e-22 79.9 0.0 4.3e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 CDO70581.1 - 0.00014 22.6 0.1 0.00052 20.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDO70581.1 - 0.002 18.0 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CDO70581.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CDO70581.1 - 0.042 12.9 0.0 0.088 11.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Methyltransf_32 PF13679.1 CDO70581.1 - 0.084 12.5 0.1 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain GBP PF02263.14 CDO70581.1 - 0.14 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain PNK3P PF08645.6 CDO70582.1 - 7.6e-45 152.2 0.0 2.2e-44 150.6 0.0 1.8 2 1 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 CDO70582.1 - 9.5e-19 67.6 0.0 4.1e-18 65.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDO70582.1 - 6.4e-06 25.4 0.0 0.045 12.8 0.0 2.6 2 1 0 3 3 3 2 Zeta toxin Hydrolase_6 PF13344.1 CDO70582.1 - 0.0009 19.0 0.1 0.023 14.6 0.0 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CDO70582.1 - 0.0029 17.8 0.0 0.12 12.6 0.0 2.4 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase KTI12 PF08433.5 CDO70582.1 - 0.003 16.8 1.1 0.026 13.7 0.2 2.3 2 1 0 2 2 2 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 CDO70582.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NIF PF03031.13 CDO70582.1 - 0.053 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase DAGK_cat PF00781.19 CDO70583.1 - 5.3e-16 58.2 0.0 9e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ADK PF00406.17 CDO70584.1 - 7.2e-46 155.7 0.1 1.5e-45 154.7 0.1 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CDO70584.1 - 8.5e-08 32.5 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CDO70584.1 - 2.6e-07 30.1 1.0 0.0034 16.7 0.3 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 CDO70584.1 - 8.5e-07 29.8 0.0 1.4e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDO70584.1 - 2.6e-05 24.1 0.1 0.00035 20.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDO70584.1 - 0.039 13.0 0.1 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 CDO70584.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain WD40 PF00400.27 CDO70585.1 - 2.1e-05 24.1 2.6 0.00025 20.7 0.1 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Fungal_trans PF04082.13 CDO70586.1 - 1.5e-18 66.6 0.4 3.2e-18 65.5 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Uricase PF01014.13 CDO70587.1 - 9.3e-16 58.1 0.4 1.1e-15 57.9 0.3 1.0 1 0 0 1 1 1 1 Uricase zf-C2H2 PF00096.21 CDO70588.1 - 0.093 13.1 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Aldo_ket_red PF00248.16 CDO70589.1 - 6.5e-50 169.5 0.0 7.9e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_11 PF13414.1 CDO70590.1 - 2.7e-24 84.6 4.1 6e-12 45.0 0.2 4.4 4 1 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 CDO70590.1 - 6.6e-21 72.9 2.5 2e-05 23.9 0.3 5.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CDO70590.1 - 2.1e-16 58.4 12.7 0.0018 18.0 0.4 6.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 CDO70590.1 - 7.2e-14 51.0 16.7 0.00065 20.1 0.1 7.0 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CDO70590.1 - 9.6e-13 47.2 9.2 0.091 13.0 0.0 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 CDO70590.1 - 1.7e-12 47.4 7.6 1.3e-07 31.8 0.2 4.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 CDO70590.1 - 6e-12 45.8 10.8 7.9e-07 29.5 0.2 5.1 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CDO70590.1 - 2.8e-10 40.0 11.5 1.3e-05 25.0 0.2 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 CDO70590.1 - 7e-08 32.5 1.1 0.00036 20.6 0.3 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CDO70590.1 - 2.3e-06 26.9 0.8 0.43 10.4 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 CDO70590.1 - 7e-06 26.0 5.8 0.35 11.0 0.6 5.1 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDO70590.1 - 1.1e-05 25.1 5.3 0.013 15.3 0.4 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CDO70590.1 - 1.5e-05 24.4 8.7 1.1 9.2 0.0 6.0 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CDO70590.1 - 0.015 15.6 0.9 40 4.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 CDO70590.1 - 0.2 11.5 1.4 14 5.6 0.1 4.1 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain F-box-like PF12937.2 CDO70591.1 - 6.1e-05 22.6 0.2 0.00013 21.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO70591.1 - 0.001 18.6 0.3 0.005 16.4 0.2 2.1 1 1 0 1 1 1 1 F-box domain PRA1 PF03208.14 CDO70592.1 - 3.7e-23 81.5 8.1 2.4e-18 65.9 3.0 2.1 2 0 0 2 2 2 2 PRA1 family protein PAS PF00989.19 CDO70593.1 - 7e-05 22.5 0.0 0.00011 21.9 0.0 1.4 1 1 0 1 1 1 1 PAS fold PAS_9 PF13426.1 CDO70593.1 - 0.0098 16.2 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 1 PAS domain Zn_clus PF00172.13 CDO70594.1 - 2.3e-05 24.1 11.2 3.7e-05 23.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec8_exocyst PF04048.9 CDO70595.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain WD40 PF00400.27 CDO70596.1 - 2.3e-55 182.6 21.0 1.2e-11 43.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CDO70596.1 - 0.00033 18.9 5.5 0.41 8.7 0.2 3.7 2 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF1513 PF07433.6 CDO70596.1 - 0.0021 17.0 0.0 0.21 10.4 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 CDO70596.1 - 0.0091 14.3 0.1 0.68 8.1 0.1 2.4 2 1 1 3 3 3 2 Cytochrome D1 heme domain DUF1416 PF07210.7 CDO70596.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) PD40 PF07676.7 CDO70596.1 - 0.072 12.7 0.8 15 5.4 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat IU_nuc_hydro PF01156.14 CDO70597.1 - 1.1e-42 146.3 0.0 1.5e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MFS_1 PF07690.11 CDO70598.1 - 9.1e-10 37.7 30.9 9.1e-10 37.7 21.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily bZIP_1 PF00170.16 CDO70600.1 - 7.6e-05 22.5 4.5 0.00012 21.8 3.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CDO70600.1 - 0.00046 19.9 3.0 0.00073 19.3 2.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DUF904 PF06005.7 CDO70600.1 - 0.009 16.2 0.1 0.015 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF2454 PF10521.4 CDO70603.1 - 0.071 12.1 0.2 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) Methyltransf_25 PF13649.1 CDO70605.1 - 7e-08 32.7 0.1 2.5e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO70605.1 - 4.2e-06 26.4 0.0 5.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDO70605.1 - 0.022 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CDO70605.1 - 0.023 15.1 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CDO70605.1 - 0.049 14.2 0.0 0.081 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ADH_N PF08240.7 CDO70606.1 - 5.3e-25 87.3 1.6 8.5e-25 86.6 1.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO70606.1 - 1.6e-16 60.0 0.2 1.3e-15 57.0 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO70606.1 - 3.2e-06 28.0 0.0 5.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase VHS PF00790.14 CDO70608.1 - 9.9e-39 132.1 0.0 2.1e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 CDO70608.1 - 8.9e-12 44.8 6.7 8.2e-09 35.3 0.0 3.0 3 0 0 3 3 3 2 GAT domain HTH_29 PF13551.1 CDO70608.1 - 0.03 14.4 0.1 0.97 9.6 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn helix Med15 PF09606.5 CDO70608.1 - 0.52 8.4 36.8 0.92 7.6 25.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal vATP-synt_E PF01991.13 CDO70609.1 - 5.8e-55 185.6 9.5 6.7e-55 185.4 6.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Meth_synt_2 PF01717.13 CDO70609.1 - 0.031 13.2 0.7 0.051 12.5 0.5 1.4 1 1 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain Phlebovirus_NSM PF07246.6 CDO70609.1 - 0.29 10.2 3.4 0.39 9.8 2.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PP-binding PF00550.20 CDO70610.1 - 0.007 16.6 0.0 0.025 14.8 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site DUF3530 PF12048.3 CDO70612.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Pyridoxal_deC PF00282.14 CDO70613.1 - 3.4e-62 210.0 0.0 4.6e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CDO70613.1 - 2.1e-05 23.4 0.0 2.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Con-6 PF10346.4 CDO70614.1 - 1.5e-28 97.9 6.2 2.6e-15 55.5 0.7 2.2 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 CDO70614.1 - 0.00073 19.0 5.3 0.0012 18.4 0.7 2.0 1 1 0 2 2 2 1 SpoIIIAH-like protein Toxin_52 PF15605.1 CDO70614.1 - 0.013 15.4 1.2 0.24 11.2 0.1 2.0 1 1 1 2 2 2 0 Putative toxin 52 YhzD PF14120.1 CDO70614.1 - 0.97 9.3 3.3 24 4.9 0.0 2.4 2 1 0 2 2 2 0 YhzD-like protein ATP-synt_DE PF00401.15 CDO70614.1 - 1.6 8.6 6.7 0.36 10.7 2.0 1.8 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain MFS_1 PF07690.11 CDO70615.1 - 3e-21 75.5 77.2 2.3e-17 62.7 31.4 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Pil1 PF13805.1 CDO70616.1 - 2.9e-15 56.1 0.6 8.2e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 Eisosome component PIL1 IFT57 PF10498.4 CDO70616.1 - 0.1 11.3 1.7 0.17 10.5 1.1 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Pkinase PF00069.20 CDO70618.1 - 2.1e-41 141.8 0.0 6.5e-28 97.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70618.1 - 4.3e-21 75.1 0.0 6.3e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO70618.1 - 0.011 15.4 0.2 0.024 14.3 0.2 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C2H2_4 PF13894.1 CDO70618.1 - 0.063 13.6 0.3 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Pkinase PF00069.20 CDO70620.1 - 1.4e-47 162.0 0.0 1.8e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70620.1 - 6.5e-29 100.7 0.0 7.7e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO70620.1 - 0.00023 20.2 0.0 0.00037 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDO70620.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDO70620.1 - 0.1 12.3 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family FA_desaturase PF00487.19 CDO70622.1 - 1.1e-16 61.0 25.5 5.4e-16 58.8 17.7 2.0 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 CDO70622.1 - 5.8e-08 32.8 0.0 9.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Alpha-L-AF_C PF06964.7 CDO70623.1 - 2.7e-32 111.9 0.0 1.2e-31 109.8 0.0 2.1 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_6 PF03422.10 CDO70623.1 - 0.012 15.7 6.9 0.22 11.7 1.8 2.5 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) Gmad2 PF10648.4 CDO70623.1 - 0.032 14.3 0.2 0.1 12.7 0.1 1.9 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination Lactamase_B_2 PF12706.2 CDO70624.1 - 1.6e-26 93.0 0.0 3.3e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CDO70624.1 - 1.5e-07 31.2 0.0 1.7e-06 27.8 0.0 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 CDO70624.1 - 2.2e-07 30.2 0.0 5.8e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Pkinase PF00069.20 CDO70626.1 - 1.3e-49 168.7 0.0 1.7e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70626.1 - 1.4e-26 93.1 0.0 1.7e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO70626.1 - 3e-05 23.8 0.1 0.0014 18.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CDO70626.1 - 0.00066 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CDO70626.1 - 0.0027 16.5 0.2 0.004 16.0 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CDO70626.1 - 0.0028 16.6 0.0 0.017 14.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 CDO70626.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 CDO70627.1 - 4e-56 190.0 0.0 5.6e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70627.1 - 1.5e-32 112.7 0.0 1.9e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO70627.1 - 5.1e-05 22.3 0.0 0.00051 19.0 0.0 2.1 1 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 CDO70627.1 - 0.003 16.9 0.1 0.043 13.1 0.0 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CDO70627.1 - 0.028 13.2 0.7 0.05 12.3 0.1 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CDO70627.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BIR PF00653.16 CDO70628.1 - 5.5e-34 116.4 1.8 1.3e-16 60.7 0.4 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain AT_hook PF02178.14 CDO70628.1 - 0.0025 17.3 5.0 0.029 13.9 3.4 3.1 1 0 0 1 1 1 1 AT hook motif WAPL PF07814.8 CDO70629.1 - 3.3e-16 58.9 0.0 2.2e-15 56.2 0.0 2.0 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DUF3538 PF12057.3 CDO70629.1 - 0.052 13.1 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) RRM_6 PF14259.1 CDO70630.1 - 1.7e-08 34.3 0.0 4.1e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CDO70630.1 - 2.5e-05 23.8 4.9 4.1e-05 23.1 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 CDO70630.1 - 8.1e-05 22.1 0.0 0.00025 20.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.1 CDO70630.1 - 0.0016 18.1 6.3 0.0029 17.2 4.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CDO70630.1 - 0.0021 17.6 5.7 0.004 16.7 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 CDO70630.1 - 0.0024 17.6 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 CDO70630.1 - 0.99 9.4 6.4 1.8 8.6 4.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO70630.1 - 1.1 9.1 6.4 2.3 8.1 4.4 1.6 1 0 0 1 1 1 0 Ring finger domain MRJP PF03022.11 CDO70631.1 - 4.1e-23 82.0 0.0 1.3e-22 80.3 0.0 1.7 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 CDO70631.1 - 0.0024 17.2 0.0 0.11 11.8 0.0 2.6 2 1 1 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region DUF2603 PF10788.4 CDO70632.1 - 0.071 12.8 0.1 0.097 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) DNA_mis_repair PF01119.14 CDO70633.1 - 9.6e-29 99.2 0.1 2e-28 98.2 0.1 1.6 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Ribosomal_L4 PF00573.17 CDO70635.1 - 2.5e-44 150.9 1.8 4.7e-44 150.0 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CDO70635.1 - 5.7e-29 99.8 3.0 5.7e-29 99.8 2.1 2.4 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Pkinase PF00069.20 CDO70636.1 - 5.5e-55 186.3 0.0 7.8e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70636.1 - 2.5e-30 105.3 0.1 8.6e-25 87.2 0.0 3.3 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CDO70636.1 - 9e-05 22.3 1.4 0.017 14.8 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 CDO70636.1 - 0.00028 20.2 0.0 0.00092 18.6 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 CDO70636.1 - 0.072 12.0 0.0 9.3 5.1 0.0 2.9 3 0 0 3 3 3 0 Kinase-like Peptidase_S10 PF00450.17 CDO70637.1 - 1.4e-73 248.5 1.3 1.8e-73 248.1 0.9 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase FERM_C PF09380.5 CDO70637.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 FERM C-terminal PH-like domain ATXN-1_C PF12547.3 CDO70638.1 - 0.055 13.4 1.3 0.12 12.2 0.9 1.6 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator DUF3932 PF13068.1 CDO70638.1 - 0.099 12.7 0.5 0.21 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) Coq4 PF05019.8 CDO70639.1 - 2e-92 308.1 0.0 2.4e-92 307.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Aminotran_1_2 PF00155.16 CDO70640.1 - 1.4e-29 103.2 0.0 1.7e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CDO70640.1 - 9.9e-09 34.2 0.0 1.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase UPF0014 PF03649.8 CDO70641.1 - 4.7e-39 134.0 9.4 6.2e-39 133.6 6.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Denso_VP4 PF02336.10 CDO70641.1 - 0.019 13.9 0.1 0.027 13.5 0.1 1.1 1 0 0 1 1 1 0 Capsid protein VP4 GHMP_kinases_N PF00288.21 CDO70641.1 - 0.34 11.0 2.2 4.7 7.3 0.7 2.9 3 1 0 3 3 3 0 GHMP kinases N terminal domain BPD_transp_1 PF00528.17 CDO70641.1 - 1.5 8.3 13.4 0.06 12.8 3.8 2.2 1 1 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component NADH5_C PF06455.6 CDO70641.1 - 3.9 6.7 8.6 1.8 7.9 2.1 2.7 3 0 0 3 3 3 0 NADH dehydrogenase subunit 5 C-terminus ABC2_membrane PF01061.19 CDO70642.1 - 6.6e-34 116.9 21.7 6.6e-34 116.9 15.1 1.6 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.22 CDO70642.1 - 1.9e-26 92.9 0.0 3.8e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CDO70642.1 - 4.1e-08 33.5 2.0 5e-07 29.9 0.2 2.7 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 CDO70642.1 - 2.6e-06 26.7 25.0 2.6e-06 26.7 17.3 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein EGF_2 PF07974.8 CDO70642.1 - 0.00015 21.8 9.8 0.00015 21.8 6.8 3.7 3 0 0 3 3 2 2 EGF-like domain AAA_25 PF13481.1 CDO70642.1 - 0.0012 18.2 0.1 0.075 12.4 0.2 2.3 2 0 0 2 2 2 1 AAA domain hEGF PF12661.2 CDO70642.1 - 0.0037 17.2 25.8 0.0085 16.1 1.7 4.4 4 0 0 4 4 3 2 Human growth factor-like EGF AAA_29 PF13555.1 CDO70642.1 - 0.005 16.3 0.1 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CDO70642.1 - 0.0054 15.9 0.1 0.015 14.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 CDO70642.1 - 0.01 14.8 0.0 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.10 CDO70642.1 - 0.027 13.1 0.0 0.04 12.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CDO70642.1 - 0.075 13.8 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 CDO70642.1 - 0.078 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CDO70642.1 - 0.088 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.1 CDO70642.1 - 0.1 12.5 0.0 0.39 10.6 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CDO70642.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 CDO70642.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain GBP PF02263.14 CDO70642.1 - 0.18 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain DUF87 PF01935.12 CDO70642.1 - 0.51 10.1 0.9 0.9 9.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 Ala_racemase_N PF01168.15 CDO70643.1 - 1.9e-40 138.7 0.5 8.2e-40 136.6 0.3 1.8 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3708 PF12501.3 CDO70643.1 - 0.066 13.0 1.0 0.14 11.9 0.1 1.9 3 0 0 3 3 3 0 Phosphate ATP-binding cassette transporter ADH_zinc_N PF00107.21 CDO70644.1 - 2.4e-15 56.2 0.0 4.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO70644.1 - 5.8e-09 36.9 0.1 3.5e-08 34.3 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase PhoH PF02562.11 CDO70644.1 - 0.033 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DFP PF04127.10 CDO70644.1 - 0.054 13.1 0.0 2.8 7.5 0.0 2.3 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Citrate_synt PF00285.16 CDO70645.1 - 1.9e-104 349.1 0.1 4.2e-96 321.7 0.0 2.0 2 0 0 2 2 2 2 Citrate synthase XPG_I PF00867.13 CDO70647.1 - 2.5e-26 91.5 0.2 9.9e-26 89.6 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 CDO70647.1 - 8.2e-22 77.3 0.0 2.1e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain OGFr_N PF04664.8 CDO70647.1 - 0.037 13.3 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region Methyltransf_18 PF12847.2 CDO70648.1 - 7.8e-13 48.9 0.0 1.6e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO70648.1 - 5.8e-11 42.7 0.0 1.6e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO70648.1 - 4.8e-09 36.1 0.0 9.3e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDO70648.1 - 2.1e-07 30.2 0.0 3.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CDO70648.1 - 2.2e-07 31.1 0.0 5.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO70648.1 - 1.5e-06 27.9 0.0 2.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDO70648.1 - 2.4e-06 27.0 0.0 4.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 CDO70648.1 - 8.6e-06 25.1 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 CDO70648.1 - 9e-06 25.7 0.0 4e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO70648.1 - 0.00013 22.3 0.0 0.00034 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CDO70648.1 - 0.0026 17.4 0.0 0.031 13.9 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.14 CDO70648.1 - 0.0054 16.7 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 CDO70648.1 - 0.0062 15.6 0.0 0.057 12.4 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 CDO70648.1 - 0.0069 15.5 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 CDO70648.1 - 0.098 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Peptidase_M24 PF00557.19 CDO70649.1 - 1.8e-26 92.9 0.2 2.6e-26 92.4 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Aminotran_1_2 PF00155.16 CDO70650.1 - 6.4e-19 68.1 0.0 8.1e-09 34.8 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Aminotran_MocR PF12897.2 CDO70650.1 - 2.6e-08 32.8 0.0 3.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase RasGAP PF00616.14 CDO70651.1 - 6.7e-54 182.5 0.0 2e-53 181.0 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 CDO70651.1 - 1.3e-38 131.9 0.4 3e-38 130.6 0.3 1.7 1 0 0 1 1 1 1 RasGAP C-terminus DUF972 PF06156.8 CDO70651.1 - 0.0092 16.3 3.4 2 8.8 0.0 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF972) Herpes_UL14 PF03580.9 CDO70651.1 - 0.063 13.0 5.7 0.023 14.5 1.7 1.9 2 0 0 2 2 2 0 Herpesvirus UL14-like protein Telomerase_RBD PF12009.3 CDO70652.1 - 1.8e-35 121.8 0.5 4.5e-35 120.5 0.3 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CDO70652.1 - 3.4e-11 42.9 0.1 5.6e-10 38.9 0.0 2.9 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_11 PF13414.1 CDO70653.1 - 4.8e-15 54.9 10.7 1.5e-07 30.9 0.8 3.7 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 CDO70653.1 - 2.9e-09 36.1 7.5 4.9e-05 22.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CDO70653.1 - 1.2e-07 31.7 0.4 0.00026 21.3 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO70653.1 - 1.3e-07 31.8 1.1 1.3e-07 31.8 0.8 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDO70653.1 - 5.6e-06 26.8 2.0 0.00049 20.7 0.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDO70653.1 - 1.4e-05 25.1 2.0 0.087 13.3 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDO70653.1 - 1.8e-05 24.6 3.2 0.00022 21.1 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO70653.1 - 2e-05 24.0 0.6 0.51 10.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CDO70653.1 - 2.9e-05 24.1 2.2 3.3e-05 23.9 0.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CDO70653.1 - 3.1e-05 23.4 9.2 0.0055 16.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CDO70653.1 - 0.00061 19.3 7.4 0.25 11.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat SelB-wing_2 PF09106.6 CDO70653.1 - 0.0044 16.9 0.7 0.021 14.7 0.1 2.4 2 0 0 2 2 2 1 Elongation factor SelB, winged helix TPR_17 PF13431.1 CDO70653.1 - 0.005 16.9 0.7 0.33 11.2 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat HrpE PF06188.7 CDO70653.1 - 0.035 13.8 3.2 0.053 13.2 2.2 1.4 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E TPR_21 PF09976.4 CDO70653.1 - 0.12 12.2 6.6 1.3 8.9 1.6 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat UPF0242 PF06785.6 CDO70656.1 - 0.019 13.6 1.4 0.028 13.1 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) ACOX PF01756.14 CDO70656.1 - 0.038 13.3 1.4 7.1 5.9 0.1 3.0 3 0 0 3 3 3 0 Acyl-CoA oxidase COG2 PF06148.6 CDO70656.1 - 0.044 13.6 1.8 0.73 9.7 0.2 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_M75 PF09375.5 CDO70656.1 - 0.058 12.6 0.2 0.13 11.5 0.1 1.7 1 0 0 1 1 1 0 Imelysin Phosphonate-bd PF12974.2 CDO70657.1 - 0.0002 20.8 0.0 0.00025 20.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 CDO70657.1 - 0.00023 20.8 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 CDO70657.1 - 0.0022 17.2 0.0 0.003 16.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Yip1 PF04893.12 CDO70659.1 - 1.1e-15 57.6 15.9 1.4e-15 57.1 11.0 1.2 1 0 0 1 1 1 1 Yip1 domain DUF4199 PF13858.1 CDO70659.1 - 0.00055 19.9 3.0 0.00055 19.9 2.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) DUF1282 PF06930.7 CDO70659.1 - 2.4 7.7 12.0 4 7.0 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) AAA PF00004.24 CDO70660.1 - 2.2e-41 141.1 0.0 3.9e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDO70660.1 - 2e-06 27.9 0.1 0.00037 20.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CDO70660.1 - 4.8e-06 26.5 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CDO70660.1 - 3.4e-05 22.9 0.0 6.5e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 CDO70660.1 - 0.00013 21.6 0.1 0.00075 19.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDO70660.1 - 0.00018 21.5 0.0 0.0015 18.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CDO70660.1 - 0.00054 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CDO70660.1 - 0.0028 17.5 0.1 0.0086 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CDO70660.1 - 0.0056 16.2 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CDO70660.1 - 0.0067 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDO70660.1 - 0.0073 17.1 0.8 0.018 15.8 0.1 2.0 2 1 0 2 2 1 1 AAA domain KaiC PF06745.8 CDO70660.1 - 0.0076 15.3 0.2 0.21 10.6 0.1 2.2 1 1 1 2 2 2 1 KaiC AAA_19 PF13245.1 CDO70660.1 - 0.0076 15.9 0.3 0.016 14.9 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CDO70660.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 CDO70660.1 - 0.013 15.8 0.3 0.036 14.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CDO70660.1 - 0.017 15.1 0.3 0.053 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CDO70660.1 - 0.026 13.3 0.1 0.069 11.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 CDO70660.1 - 0.027 14.1 0.1 0.43 10.2 0.1 2.4 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.1 CDO70660.1 - 0.04 13.3 0.8 2 7.7 0.2 2.4 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CDO70660.1 - 0.045 12.8 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 CDO70660.1 - 0.068 12.1 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 CDO70660.1 - 0.072 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Viral_helicase1 PF01443.13 CDO70660.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CDO70660.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 CDO70660.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CDO70660.1 - 0.13 11.7 0.2 0.4 10.2 0.2 1.7 1 0 0 1 1 1 0 AAA domain DP PF08781.5 CDO70661.1 - 0.00026 20.7 0.2 0.00046 19.8 0.1 1.4 1 0 0 1 1 1 1 Transcription factor DP V_ATPase_I PF01496.14 CDO70661.1 - 0.026 12.3 0.3 1.5 6.5 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CorA PF01544.13 CDO70661.1 - 0.085 11.8 0.2 0.085 11.8 0.1 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 CDO70661.1 - 0.89 9.3 4.8 0.71 9.6 0.7 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF972 PF06156.8 CDO70661.1 - 1.2 9.5 3.5 3 8.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 CDO70661.1 - 3.3 7.2 7.2 5.7 6.5 0.9 2.9 3 0 0 3 3 3 0 Septum formation initiator PEP-utilisers_N PF05524.8 CDO70661.1 - 6.8 6.5 13.1 0.034 13.9 1.3 2.8 3 1 0 3 3 3 0 PEP-utilising enzyme, N-terminal SlyX PF04102.7 CDO70661.1 - 7 7.1 9.2 8.1 6.9 1.9 2.8 2 1 0 2 2 2 0 SlyX PH PF00169.24 CDO70664.1 - 7.4e-05 22.9 0.0 0.0024 18.0 0.0 2.7 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 CDO70664.1 - 0.001 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain NOA36 PF06524.7 CDO70664.1 - 6.3 5.9 3.0 10 5.2 2.1 1.2 1 0 0 1 1 1 0 NOA36 protein CCDC92 PF14916.1 CDO70666.1 - 0.0085 15.6 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Coiled-coil domain of unknown function GAD PF02938.9 CDO70666.1 - 0.018 15.1 0.0 0.092 12.9 0.0 1.9 2 0 0 2 2 2 0 GAD domain HALZ PF02183.13 CDO70666.1 - 0.11 12.1 0.7 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlxA PF14282.1 CDO70666.1 - 0.22 11.4 2.4 0.45 10.4 1.7 1.5 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.10 CDO70666.1 - 0.27 10.7 1.6 0.72 9.3 1.1 1.7 1 0 0 1 1 1 0 Septum formation initiator Abhydrolase_2 PF02230.11 CDO70668.1 - 9.1e-25 87.3 0.0 3.8e-23 82.0 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 CDO70668.1 - 1.5e-07 31.5 2.0 0.00016 21.6 1.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO70668.1 - 6.8e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 CDO70668.1 - 0.0002 20.6 0.0 0.00043 19.5 0.0 1.5 2 0 0 2 2 2 1 Secretory lipase Peptidase_S9 PF00326.16 CDO70668.1 - 0.00064 19.0 0.0 0.0026 17.0 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family SpoIIE PF07228.7 CDO70670.1 - 0.0003 20.5 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CDO70670.1 - 0.0021 17.4 0.3 0.28 10.5 0.0 2.7 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.1 CDO70670.1 - 0.0069 15.8 0.1 0.047 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C DUF2360 PF10152.4 CDO70670.1 - 0.018 15.3 7.8 0.037 14.3 0.2 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3452 PF11934.3 CDO70670.1 - 0.023 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF4451 PF14616.1 CDO70671.1 - 2.1e-23 82.4 0.4 7.9e-12 45.0 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4451) AAA PF00004.24 CDO70672.1 - 1.2e-54 184.0 0.0 7.5e-44 149.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CDO70672.1 - 2.7e-21 75.4 0.8 6.2e-21 74.2 0.5 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 CDO70672.1 - 6.3e-08 32.8 10.4 0.0067 16.4 0.1 4.9 4 2 2 6 6 5 2 AAA ATPase domain AAA_14 PF13173.1 CDO70672.1 - 1.1e-06 28.5 0.0 0.052 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CDO70672.1 - 1.9e-06 28.7 0.0 0.0034 18.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 CDO70672.1 - 3.8e-06 27.0 2.9 0.19 11.8 0.0 4.6 4 2 0 4 4 2 2 AAA domain AAA_19 PF13245.1 CDO70672.1 - 2.6e-05 23.8 0.8 0.16 11.7 0.1 3.4 3 0 0 3 3 2 2 Part of AAA domain Bac_DnaA PF00308.13 CDO70672.1 - 2.7e-05 23.9 0.0 0.0036 16.9 0.0 2.6 3 0 0 3 3 2 1 Bacterial dnaA protein Zeta_toxin PF06414.7 CDO70672.1 - 2.8e-05 23.3 0.0 0.11 11.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 CDO70672.1 - 5.1e-05 22.9 0.2 0.28 10.8 0.0 3.8 3 1 0 3 3 3 1 NACHT domain RuvB_N PF05496.7 CDO70672.1 - 6e-05 22.2 0.0 0.0041 16.1 0.0 2.9 4 0 0 4 4 3 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CDO70672.1 - 7.5e-05 21.6 0.0 0.078 11.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_5 PF07728.9 CDO70672.1 - 0.00011 21.9 0.1 0.41 10.3 0.0 3.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CDO70672.1 - 0.00035 20.0 2.4 2.2 7.6 0.1 4.0 2 2 1 4 4 4 1 AAA domain IstB_IS21 PF01695.12 CDO70672.1 - 0.00037 19.9 0.2 0.5 9.7 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein ABC_tran PF00005.22 CDO70672.1 - 0.00039 20.7 0.0 0.095 12.9 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_2 PF07724.9 CDO70672.1 - 0.00073 19.4 0.0 0.035 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 CDO70672.1 - 0.0013 18.9 0.0 0.79 9.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF2075 PF09848.4 CDO70672.1 - 0.0028 16.6 0.0 1.8 7.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CDO70672.1 - 0.0032 17.0 1.1 0.043 13.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CDO70672.1 - 0.0035 17.2 0.0 0.069 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CDO70672.1 - 0.0037 16.7 0.0 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CDO70672.1 - 0.0056 16.9 0.0 0.69 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CDO70672.1 - 0.0058 16.3 0.0 3.1 7.4 0.0 3.0 2 1 1 3 3 3 1 Archaeal ATPase Mg_chelatase PF01078.16 CDO70672.1 - 0.0092 15.1 0.2 0.58 9.2 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CDO70672.1 - 0.01 15.4 0.4 3.5 7.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 CDO70672.1 - 0.011 15.3 0.0 0.25 10.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 CDO70672.1 - 0.018 14.6 0.0 0.6 9.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 CDO70672.1 - 0.019 13.8 0.0 0.44 9.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 CDO70672.1 - 0.02 14.6 0.1 0.79 9.4 0.0 2.4 2 0 0 2 2 2 0 NTPase Rad17 PF03215.10 CDO70672.1 - 0.022 13.4 0.0 0.45 9.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 CDO70672.1 - 0.034 12.9 0.3 1.3 7.7 0.0 2.5 2 1 0 2 2 2 0 NB-ARC domain Cytidylate_kin2 PF13189.1 CDO70672.1 - 0.047 13.5 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family HD PF01966.17 CDO70672.1 - 0.053 13.5 1.2 0.74 9.8 0.0 2.9 3 0 0 3 3 3 0 HD domain AAA_31 PF13614.1 CDO70672.1 - 0.075 12.9 0.1 6.1 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CDO70672.1 - 0.099 12.2 0.1 13 5.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 APS_kinase PF01583.15 CDO70672.1 - 0.12 12.0 0.1 2.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Adenylylsulphate kinase KaiC PF06745.8 CDO70672.1 - 0.15 11.1 0.3 6.6 5.7 0.0 2.9 3 0 0 3 3 3 0 KaiC cobW PF02492.14 CDO70672.1 - 0.19 11.1 0.6 7.4 5.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain F-box-like PF12937.2 CDO70673.1 - 0.0019 17.8 1.3 0.0086 15.7 0.9 2.1 1 1 0 1 1 1 1 F-box-like Saccharop_dh PF03435.13 CDO70674.1 - 4e-76 256.5 0.0 5.1e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_C PF01262.16 CDO70674.1 - 5e-14 52.2 0.0 3.4e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 CDO70674.1 - 6.2e-11 42.4 0.0 1e-09 38.5 0.0 2.8 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain Shikimate_DH PF01488.15 CDO70674.1 - 0.00036 20.6 0.0 0.00088 19.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 CDO70674.1 - 0.027 14.4 0.1 0.059 13.3 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding MFS_1 PF07690.11 CDO70676.1 - 8.8e-17 60.8 51.4 7.2e-11 41.3 26.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S10 PF00338.17 CDO70677.1 - 9.7e-25 86.2 0.0 1.7e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DivIC PF04977.10 CDO70680.1 - 0.81 9.2 3.7 1.4 8.4 2.6 1.3 1 0 0 1 1 1 0 Septum formation initiator TFIIF_alpha PF05793.7 CDO70680.1 - 2.8 6.2 16.6 3.5 5.8 11.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PolyA_pol_arg_C PF12626.2 CDO70684.1 - 0.0076 15.8 0.4 0.017 14.7 0.3 1.5 1 0 0 1 1 1 1 Polymerase A arginine-rich C-terminus NOB1_Zn_bind PF08772.6 CDO70684.1 - 0.049 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Methyltransf_26 PF13659.1 CDO70685.1 - 2e-05 24.5 0.0 9.7e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO70685.1 - 0.0021 17.6 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO70685.1 - 0.006 17.0 0.0 0.022 15.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO70685.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PALP PF00291.20 CDO70686.1 - 3.5e-53 180.8 0.0 5.7e-53 180.1 0.0 1.2 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_3 PF13377.1 CDO70686.1 - 0.029 14.3 0.0 0.15 12.0 0.0 2.2 1 1 0 1 1 1 0 Periplasmic binding protein-like domain Glyco_hydro_31 PF01055.21 CDO70687.1 - 1.1e-91 307.9 0.0 2.4e-64 217.8 0.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CDO70687.1 - 2.5e-18 65.6 0.2 5.5e-18 64.5 0.1 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like Myb_DNA-bind_4 PF13837.1 CDO70688.1 - 2e-09 37.4 0.1 3.2e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO70688.1 - 4.3e-07 30.4 0.1 7.1e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO70688.1 - 4.3e-05 23.3 0.0 9.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO70688.1 - 0.0074 16.3 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CDO70688.1 - 0.13 12.2 1.0 0.31 11.1 0.7 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain CENP-B_dimeris PF09026.5 CDO70688.1 - 0.5 10.6 6.0 0.97 9.7 4.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PALP PF00291.20 CDO70689.1 - 2.3e-57 194.5 0.2 3.2e-57 194.0 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2346 PF09803.4 CDO70690.1 - 8.6e-10 38.3 1.7 3.6e-09 36.3 1.2 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Copper-bind PF00127.15 CDO70691.1 - 2.8e-05 24.2 0.1 6.1e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family GARS_A PF01071.14 CDO70691.1 - 0.16 11.5 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DNA_pol_E_B PF04042.11 CDO70693.1 - 7.6e-39 133.1 0.2 2.6e-37 128.1 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pyridoxal_deC PF00282.14 CDO70694.1 - 8e-63 212.1 0.0 1.1e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CDO70694.1 - 1.4e-06 27.3 0.0 2.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Hid1 PF12722.2 CDO70695.1 - 3.4e-140 468.4 0.0 1.6e-139 466.2 0.0 1.5 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 CDO70695.1 - 5.5e-64 216.4 0.0 7.8e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein AvrRpt-cleavage PF05627.6 CDO70696.1 - 0.22 10.6 1.1 0.92 8.5 0.1 2.3 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr DGF-1_C PF11040.3 CDO70696.1 - 4.6 7.1 7.3 20 5.1 5.1 2.1 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF605 PF04652.11 CDO70696.1 - 6.5 6.0 15.5 8.8 5.6 10.7 1.3 1 0 0 1 1 1 0 Vta1 like Atg8 PF02991.11 CDO70698.1 - 2.2e-52 175.3 0.1 2.6e-52 175.1 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CDO70698.1 - 5.6e-07 29.6 0.0 7.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 LRR19-TM PF15176.1 CDO70698.1 - 0.15 11.7 0.0 9.6 5.9 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Rubredoxin PF00301.15 CDO70699.1 - 0.024 14.5 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Rubredoxin DUF4658 PF15555.1 CDO70699.1 - 0.031 14.1 0.4 0.053 13.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) PRP21_like_P PF12230.3 CDO70700.1 - 2.3e-56 190.8 22.2 2.3e-56 190.8 15.4 2.8 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CDO70700.1 - 6.2e-35 118.6 0.4 1.6e-16 59.7 0.0 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 CDO70700.1 - 0.00022 20.5 0.0 0.00046 19.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CDO70700.1 - 0.065 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CDO70700.1 - 0.068 13.3 0.1 0.068 13.3 0.0 3.1 4 1 0 4 4 4 0 DUF2407 ubiquitin-like domain L31 PF09784.4 CDO70701.1 - 2.5e-40 136.7 0.5 2.8e-40 136.5 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 CMS1 PF14617.1 CDO70702.1 - 1e-80 270.4 0.2 1.2e-80 270.1 0.2 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AOX PF01786.12 CDO70702.1 - 0.037 13.4 0.0 0.085 12.2 0.0 1.6 1 1 0 1 1 1 0 Alternative oxidase RNase_T PF00929.19 CDO70703.1 - 4.5e-10 40.0 0.0 0.0021 18.3 0.0 3.7 4 0 0 4 4 4 3 Exonuclease Ndc80_HEC PF03801.8 CDO70705.1 - 9.5e-33 112.8 0.0 2.2e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family Fib_alpha PF08702.5 CDO70705.1 - 0.00076 19.6 24.6 0.00095 19.3 2.8 3.3 2 1 1 3 3 3 2 Fibrinogen alpha/beta chain family DUF342 PF03961.8 CDO70705.1 - 0.39 9.0 18.3 0.25 9.7 5.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF342) zf-C4H2 PF10146.4 CDO70705.1 - 1 9.3 15.1 0.04 13.9 4.1 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein DUF972 PF06156.8 CDO70705.1 - 2 8.8 27.9 0.26 11.6 3.0 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 CDO70705.1 - 6 7.1 13.6 35 4.7 0.0 5.0 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Mog1 PF04603.7 CDO70706.1 - 3.2e-32 111.3 0.2 4e-32 111.0 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Med9 PF07544.8 CDO70707.1 - 0.028 14.1 1.9 0.028 14.1 1.3 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ERM PF00769.14 CDO70707.1 - 0.038 13.5 23.9 0.22 11.0 5.5 2.4 3 0 0 3 3 3 0 Ezrin/radixin/moesin family HALZ PF02183.13 CDO70707.1 - 0.098 12.3 7.2 0.47 10.1 1.9 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 CDO70707.1 - 0.11 12.8 12.5 1.4 9.2 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) WD40_alt PF14077.1 CDO70707.1 - 0.2 11.2 4.3 0.48 10.0 3.0 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif bZIP_1 PF00170.16 CDO70707.1 - 0.21 11.5 12.8 0.76 9.7 2.0 2.6 2 0 0 2 2 2 0 bZIP transcription factor Striatin PF08232.7 CDO70707.1 - 0.43 10.8 13.5 2 8.7 3.5 2.7 3 0 0 3 3 3 0 Striatin family CENP-Q PF13094.1 CDO70707.1 - 0.45 10.5 24.0 1.8 8.5 5.5 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIVA PF05103.8 CDO70707.1 - 0.55 10.2 21.4 0.19 11.7 3.4 2.5 2 1 0 2 2 2 0 DivIVA protein MOSC_N PF03476.11 CDO70707.1 - 0.62 9.7 3.4 2.4 7.8 0.2 2.2 2 0 0 2 2 2 0 MOSC N-terminal beta barrel domain GrpE PF01025.14 CDO70707.1 - 1.5 8.3 16.2 0.57 9.7 2.5 2.2 2 0 0 2 2 2 0 GrpE GAS PF13851.1 CDO70707.1 - 2.4 7.3 16.2 0.16 11.1 2.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 CDO70707.1 - 2.6 7.5 11.9 3.8 7.0 2.3 2.1 2 0 0 2 2 2 0 IncA protein DUF904 PF06005.7 CDO70707.1 - 2.7 8.3 16.3 7.4 6.9 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Peptidase_S46 PF10459.4 CDO70707.1 - 3.4 5.9 9.9 1.7 6.9 2.5 2.0 2 0 0 2 2 2 0 Peptidase S46 DUF2681 PF10883.3 CDO70707.1 - 3.8 7.7 12.2 1 9.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ADIP PF11559.3 CDO70707.1 - 6.4 6.6 14.9 1.7 8.5 2.8 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cpn60_TCP1 PF00118.19 CDO70709.1 - 3.3e-135 451.4 9.5 3.7e-135 451.2 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 CDO70709.1 - 0.0048 16.1 0.1 0.015 14.5 0.0 1.9 2 1 0 2 2 2 1 Telomere recombination ATP-synt_Eps PF04627.8 CDO70709.1 - 0.58 9.7 2.4 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ATP synthase epsilon chain TPR_11 PF13414.1 CDO70710.1 - 3.9e-27 93.7 14.8 6.4e-09 35.3 1.2 5.6 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 CDO70710.1 - 9.8e-23 78.7 12.9 2.1e-05 23.9 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 CDO70710.1 - 2.2e-22 77.1 10.4 0.00021 20.9 0.0 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 CDO70710.1 - 2.7e-21 75.6 6.8 1.2e-06 28.7 0.2 6.0 4 3 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 CDO70710.1 - 1.9e-18 66.6 16.1 0.00022 21.8 0.2 6.3 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 CDO70710.1 - 1.8e-15 56.6 12.3 0.0021 17.9 0.1 5.4 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 CDO70710.1 - 4.1e-13 48.0 1.7 0.18 11.6 0.0 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 CDO70710.1 - 7.8e-13 47.5 3.0 0.073 13.3 0.1 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CDO70710.1 - 1.8e-12 46.6 8.2 0.011 16.2 0.0 7.4 2 2 6 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 CDO70710.1 - 1.5e-09 37.8 14.2 0.0015 18.6 1.0 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CDO70710.1 - 2.8e-09 36.6 4.2 2.2e-05 24.2 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CDO70710.1 - 2.8e-06 27.4 20.3 0.5 10.9 0.0 7.4 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 CDO70710.1 - 0.00058 19.0 11.0 0.18 10.8 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TOM20_plant PF06552.7 CDO70710.1 - 0.0083 15.7 0.5 5.5 6.5 0.0 3.1 1 1 3 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_7 PF13176.1 CDO70710.1 - 0.019 14.7 9.4 22 5.1 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 CDO70710.1 - 0.025 14.5 3.0 0.42 10.6 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat PPTA PF01239.17 CDO70710.1 - 0.04 13.2 0.9 7.5 6.0 0.0 2.9 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat Fis1_TPR_C PF14853.1 CDO70710.1 - 0.08 12.8 3.6 1.4 8.8 0.1 3.4 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.7 CDO70710.1 - 0.75 10.5 4.1 64 4.3 0.0 4.7 5 0 0 5 5 4 0 Sel1 repeat MIT PF04212.13 CDO70710.1 - 0.77 9.6 7.1 0.95 9.3 0.2 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain SRR1 PF07985.7 CDO70712.1 - 8.4e-16 57.6 0.2 1.4e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 SRR1 PUA PF01472.15 CDO70713.1 - 9e-16 57.3 0.0 1.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 PUA domain CRM1_C PF08767.6 CDO70714.1 - 2e-133 444.2 0.1 2e-133 444.2 0.1 3.5 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 CDO70714.1 - 4e-43 146.8 9.1 4.2e-42 143.5 4.5 3.5 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 CDO70714.1 - 4e-12 45.8 0.0 1.8e-11 43.7 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 CDO70714.1 - 0.13 12.6 1.4 7.8 6.9 0.0 3.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region UME PF08064.8 CDO70714.1 - 0.97 9.4 6.9 1.4 8.8 0.0 4.3 4 1 0 4 4 4 0 UME (NUC010) domain Spc24 PF08286.6 CDO70715.1 - 3e-11 43.0 0.0 7e-11 41.8 0.0 1.6 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Reo_sigmaC PF04582.7 CDO70715.1 - 0.011 14.8 1.4 0.015 14.5 0.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 CDO70715.1 - 2.4 8.0 6.4 1.4 8.8 0.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CAF1A PF12253.3 CDO70716.1 - 5.8e-20 71.1 2.6 5.8e-20 71.1 1.8 2.7 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A XPA_N PF01286.13 CDO70716.1 - 3.7 7.3 5.9 0.32 10.7 0.6 1.8 2 0 0 2 2 2 0 XPA protein N-terminal AAA PF00004.24 CDO70717.1 - 5e-15 55.8 0.0 8.9e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CDO70717.1 - 3.7e-12 46.2 0.0 2.2e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CDO70717.1 - 4.5e-10 38.8 0.0 4.7e-06 25.5 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CDO70717.1 - 3.3e-08 33.7 0.0 9.6e-08 32.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain Rep_fac_C PF08542.6 CDO70717.1 - 8.9e-07 28.8 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_19 PF13245.1 CDO70717.1 - 1.5e-06 27.8 0.2 2.6e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 CDO70717.1 - 1.1e-05 25.4 0.1 0.0003 20.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CDO70717.1 - 4.3e-05 22.6 0.0 8.7e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 CDO70717.1 - 8.4e-05 22.2 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CDO70717.1 - 0.00029 20.7 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CDO70717.1 - 0.0005 19.7 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CDO70717.1 - 0.00067 19.4 0.0 0.0019 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 CDO70717.1 - 0.00085 18.9 0.0 0.0027 17.3 0.0 1.7 2 1 0 2 2 1 1 AAA domain DUF2075 PF09848.4 CDO70717.1 - 0.0022 17.0 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 CDO70717.1 - 0.004 16.6 0.1 0.14 11.5 0.0 2.2 1 1 0 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 CDO70717.1 - 0.008 15.3 0.0 0.075 12.1 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CDO70717.1 - 0.0086 16.8 0.0 0.022 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CDO70717.1 - 0.0094 15.3 0.0 0.027 13.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CDO70717.1 - 0.011 15.6 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CDO70717.1 - 0.014 14.8 0.2 0.48 9.8 0.0 2.2 1 1 1 2 2 2 0 FtsK/SpoIIIE family DEAD PF00270.24 CDO70717.1 - 0.017 14.6 0.1 0.38 10.2 0.0 2.6 2 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_2 PF07724.9 CDO70717.1 - 0.036 13.9 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CDO70717.1 - 0.041 12.8 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 CDO70717.1 - 0.041 13.7 0.0 0.091 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CDO70717.1 - 0.05 12.8 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.12 CDO70717.1 - 0.081 11.7 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 CDO70717.1 - 0.088 13.1 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CDO70717.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 CDO70717.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 CDO70717.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.17 CDO70717.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase HSP70 PF00012.15 CDO70718.1 - 2.5e-244 811.7 4.9 2.8e-244 811.5 3.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CDO70718.1 - 1.4e-17 63.3 0.2 1.1e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CDO70718.1 - 0.0003 20.6 0.0 0.79 9.5 0.0 3.2 2 2 0 2 2 2 2 Cell division protein FtsA BcrAD_BadFG PF01869.15 CDO70718.1 - 0.0041 16.4 0.1 2.1 7.5 0.0 2.7 2 1 1 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.5 CDO70718.1 - 0.013 14.3 2.9 0.039 12.7 0.2 2.6 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 CDO70718.1 - 0.024 13.6 0.0 0.059 12.3 0.0 1.7 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.11 CDO70718.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF406 PF04175.7 CDO70718.1 - 0.15 12.5 2.3 0.28 11.6 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF406) Ribosomal_S2 PF00318.15 CDO70719.1 - 6.8e-47 159.4 0.0 1.9e-26 92.6 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S2 Chorismate_bind PF00425.13 CDO70720.1 - 2.3e-86 289.3 0.0 4e-86 288.5 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 CDO70720.1 - 1.7e-30 105.8 0.0 2.5e-29 102.0 0.0 2.3 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Phage_holin_3 PF05106.7 CDO70720.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) SHQ1 PF04925.10 CDO70721.1 - 8e-52 175.4 0.1 2.5e-51 173.8 0.0 1.8 1 1 1 2 2 2 1 SHQ1 protein CS PF04969.11 CDO70721.1 - 2.8e-05 24.5 0.0 4.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 CS domain PIH1 PF08190.7 CDO70721.1 - 0.0001 21.8 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 UAA PF08449.6 CDO70723.1 - 0.035 13.0 3.1 0.017 14.0 0.4 1.7 2 0 0 2 2 2 0 UAA transporter family Nuc_sug_transp PF04142.10 CDO70723.1 - 0.099 11.7 0.5 4.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter EamA PF00892.15 CDO70723.1 - 0.35 10.8 17.4 0.74 9.8 2.9 3.2 3 1 0 3 3 3 0 EamA-like transporter family E1-E2_ATPase PF00122.15 CDO70724.1 - 1.1e-68 230.7 4.9 1.1e-68 230.7 3.4 2.9 3 1 1 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CDO70724.1 - 4e-45 153.5 11.9 4.2e-45 153.5 6.5 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CDO70724.1 - 1e-31 111.0 0.0 1e-30 107.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CDO70724.1 - 6.5e-23 79.9 0.3 1.5e-21 75.5 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CDO70724.1 - 2.1e-19 69.2 0.0 4.2e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CDO70724.1 - 5.3e-15 56.0 0.0 1.5e-14 54.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDO70724.1 - 1.6e-07 31.1 1.2 2.5e-06 27.2 0.8 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CDO70724.1 - 0.02 15.1 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DPBB_1 PF03330.13 CDO70726.1 - 8.9e-10 38.4 1.2 3e-09 36.7 0.3 2.4 1 1 1 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DPBB_1 PF03330.13 CDO70727.1 - 0.002 18.1 0.1 0.0088 16.0 0.0 2.1 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SOG2 PF10428.4 CDO70727.1 - 0.0024 16.6 6.4 0.0023 16.6 4.4 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Med13_C PF06333.7 CDO70727.1 - 0.63 8.5 6.6 0.73 8.3 4.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal TFIIA PF03153.8 CDO70727.1 - 3.7 7.3 7.5 6.2 6.6 5.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF566 PF04484.7 CDO70727.1 - 8 5.8 13.3 11 5.3 9.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DPBB_1 PF03330.13 CDO70728.1 - 0.0037 17.2 0.0 0.0076 16.2 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel CDK2AP PF09806.4 CDO70728.1 - 0.8 9.9 8.8 1.6 8.9 6.1 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Macoilin PF09726.4 CDO70728.1 - 2.5 6.2 11.8 3.2 5.9 8.2 1.1 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 CDO70728.1 - 5.2 5.6 17.3 8.9 4.8 12.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SR-25 PF10500.4 CDO70729.1 - 0.0025 17.3 11.2 0.0025 17.3 7.8 3.0 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Med3 PF11593.3 CDO70729.1 - 0.0042 16.3 15.2 0.0054 16.0 10.5 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal MAP65_ASE1 PF03999.7 CDO70729.1 - 0.55 8.7 10.6 0.77 8.2 7.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RCC1 PF00415.13 CDO70730.1 - 2.6e-23 81.9 7.6 2.7e-05 24.2 0.0 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDO70730.1 - 1.2e-09 37.5 18.8 2.2e-05 23.9 0.0 6.0 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat DUF913 PF06025.7 CDO70732.1 - 0.011 14.4 0.1 0.016 14.0 0.1 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) DSBA PF01323.15 CDO70732.1 - 0.033 13.7 0.1 0.047 13.2 0.1 1.4 1 1 0 1 1 1 0 DSBA-like thioredoxin domain HTH_32 PF13565.1 CDO70732.1 - 0.039 14.7 2.5 1.6 9.5 0.4 3.0 1 1 1 2 2 2 0 Homeodomain-like domain DUF4332 PF14229.1 CDO70732.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4332) Adeno_PIX PF03955.9 CDO70732.1 - 0.2 12.1 1.8 0.5 10.9 1.2 1.9 1 1 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Hist_deacetyl PF00850.14 CDO70733.1 - 5.5e-80 268.9 0.0 7.7e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RRM_1 PF00076.17 CDO70734.1 - 1.7e-24 85.1 0.0 2e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 CDO70734.1 - 4.1e-22 76.3 0.0 2.5e-05 23.4 0.0 5.7 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 CDO70734.1 - 2.6e-17 62.5 0.0 4.5e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO70734.1 - 2.3e-13 49.7 0.0 1e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_21 PF13276.1 CDO70734.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 HTH-like domain Nop14 PF04147.7 CDO70735.1 - 0.41 8.5 6.8 0.66 7.8 4.7 1.2 1 0 0 1 1 1 0 Nop14-like family DDRGK PF09756.4 CDO70736.1 - 7.5 5.9 15.8 0.07 12.5 0.9 2.1 2 0 0 2 2 2 0 DDRGK domain RNA_pol_Rpc82 PF05645.8 CDO70737.1 - 1.3e-16 60.9 0.3 4.9e-14 52.4 0.1 3.2 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 CDO70737.1 - 1.5e-14 53.6 0.1 1.2e-11 44.2 0.1 3.4 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 CDO70737.1 - 1.9e-12 46.5 0.1 4.4e-07 29.3 0.0 4.1 4 0 0 4 4 4 2 TFIIE alpha subunit AMP-binding PF00501.23 CDO70739.1 - 1.2e-14 53.5 0.0 5.4e-14 51.3 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme SPT16 PF08644.6 CDO70740.1 - 1.4e-57 193.7 0.1 3.8e-57 192.3 0.1 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 CDO70740.1 - 4.2e-38 130.4 0.3 2.1e-37 128.1 0.0 2.4 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CDO70740.1 - 1.2e-23 83.8 0.0 1.9e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 CDO70740.1 - 3e-21 75.1 0.2 2.1e-20 72.5 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF4218 PF13960.1 CDO70741.1 - 0.18 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Abhydrolase_6 PF12697.2 CDO70743.1 - 1.1e-28 100.6 0.0 1.5e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO70743.1 - 1.7e-18 66.7 0.0 2.7e-18 66.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO70743.1 - 2.5e-16 59.9 0.0 1.3e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CDO70743.1 - 0.00016 21.4 0.0 0.00039 20.2 0.0 1.6 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 CDO70743.1 - 0.00024 20.7 0.0 0.0025 17.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 CDO70743.1 - 0.0051 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 CDO70743.1 - 0.015 14.5 0.1 0.45 9.6 0.0 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.13 CDO70743.1 - 0.015 14.5 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Ndr PF03096.9 CDO70743.1 - 0.032 12.7 0.0 0.047 12.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family Thioesterase PF00975.15 CDO70743.1 - 0.052 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.7 CDO70743.1 - 0.078 12.6 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 CDO70743.1 - 0.15 11.5 0.2 0.61 9.6 0.0 2.0 3 0 0 3 3 3 0 PGAP1-like protein DUF2048 PF09752.4 CDO70743.1 - 0.16 10.7 0.0 0.82 8.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Helicase_C PF00271.26 CDO70744.1 - 8.1e-10 38.4 0.1 9.3e-09 35.0 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 CDO70744.1 - 2.5e-06 27.9 0.1 8.2e-06 26.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 CDO70744.1 - 0.00012 22.1 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like Pkinase PF00069.20 CDO70745.1 - 9.2e-19 67.5 0.0 1.3e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70745.1 - 6.3e-10 38.5 0.0 1.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MBOAT_2 PF13813.1 CDO70746.1 - 6.3e-29 99.8 15.6 7e-15 54.8 3.7 3.6 3 0 0 3 3 3 2 Membrane bound O-acyl transferase family Arrestin_N PF00339.24 CDO70747.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Cytochrom_B561 PF03188.11 CDO70748.1 - 0.00057 19.7 6.6 0.0017 18.1 3.5 2.4 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 CDO70748.1 - 0.023 14.4 0.5 0.023 14.4 0.3 2.9 4 0 0 4 4 4 0 PepSY-associated TM helix DUF202 PF02656.10 CDO70748.1 - 0.82 9.9 6.0 1.4 9.1 0.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF202) NAD_binding_2 PF03446.10 CDO70749.1 - 3.8e-38 130.8 0.1 6.4e-38 130.1 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CDO70749.1 - 4.6e-33 113.8 0.0 9.3e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sec7 PF01369.15 CDO70750.1 - 6.1e-63 211.9 0.2 1.1e-62 211.0 0.2 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CDO70750.1 - 1.1e-19 70.4 1.4 6.9e-10 38.6 0.0 3.3 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CDO70750.1 - 0.00027 20.4 1.5 0.56 9.7 0.0 4.5 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) Proteasome PF00227.21 CDO70751.1 - 8.5e-59 198.0 0.0 1.2e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDO70751.1 - 1.2e-14 53.2 0.1 1.2e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Orthopox_B11R PF07033.6 CDO70751.1 - 0.024 14.0 0.5 3.4 7.2 0.1 3.1 3 0 0 3 3 3 0 Orthopoxvirus B11R protein Peptidase_C78 PF07910.8 CDO70753.1 - 7.8e-40 136.3 0.0 1.1e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 MAT1 PF06391.8 CDO70754.1 - 2.5e-48 164.3 11.1 2.9e-48 164.1 7.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 APG6 PF04111.7 CDO70754.1 - 1 8.3 11.2 1.5 7.7 7.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 VIT1 PF01988.14 CDO70754.1 - 1.6 8.1 5.2 2.7 7.4 3.6 1.3 1 0 0 1 1 1 0 VIT family DUF1682 PF07946.9 CDO70754.1 - 8.8 5.0 14.1 12 4.6 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LigB PF02900.13 CDO70755.1 - 1e-40 139.4 0.0 1.4e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Pkinase PF00069.20 CDO70756.1 - 3.3e-63 213.2 0.0 4e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70756.1 - 1.2e-30 106.4 0.0 1.6e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO70756.1 - 0.00026 20.0 0.0 0.00048 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Brix PF04427.13 CDO70757.1 - 9.8e-48 162.3 0.0 1.3e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain eIF-3c_N PF05470.7 CDO70757.1 - 0.67 7.9 12.0 1.1 7.2 8.3 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus BUD22 PF09073.5 CDO70757.1 - 0.74 8.8 35.9 1.2 8.1 24.9 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 CDO70757.1 - 2.7 5.7 38.1 3.9 5.2 26.4 1.2 1 0 0 1 1 1 0 Nop14-like family Cyto_heme_lyase PF01265.12 CDO70758.1 - 4.1e-77 259.2 0.0 5.3e-77 258.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase NMO PF03060.10 CDO70759.1 - 7.4e-75 252.1 1.7 9e-75 251.8 1.2 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CDO70759.1 - 5.3e-08 32.1 0.3 0.0047 15.8 0.2 2.9 3 1 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CDO70759.1 - 0.002 17.0 3.0 0.0036 16.2 2.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 CDO70759.1 - 0.068 12.1 0.4 0.1 11.5 0.3 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase WD40 PF00400.27 CDO70760.1 - 4e-23 80.3 6.8 1.2e-08 34.4 0.0 6.1 6 2 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CDO70760.1 - 5e-05 22.2 1.7 1 7.9 0.0 4.2 2 2 3 5 5 5 4 Nup133 N terminal like Nup160 PF11715.3 CDO70760.1 - 0.011 13.9 0.2 0.37 8.8 0.4 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Med4 PF10018.4 CDO70761.1 - 0.00043 19.7 4.1 0.36 10.2 0.5 2.6 2 1 1 3 3 3 2 Vitamin-D-receptor interacting Mediator subunit 4 Focal_AT PF03623.8 CDO70761.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Focal adhesion targeting region PDZ_assoc PF10600.4 CDO70761.1 - 0.3 11.4 2.2 0.65 10.3 1.5 1.5 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors Lsm_C PF14894.1 CDO70761.1 - 0.31 10.5 1.2 0.78 9.2 0.2 2.1 3 0 0 3 3 3 0 Lsm C-terminal TPR_11 PF13414.1 CDO70762.1 - 2.5e-07 30.2 15.0 0.01 15.4 0.0 6.8 6 1 2 8 8 8 2 TPR repeat TPR_12 PF13424.1 CDO70762.1 - 5.7e-07 29.3 14.3 0.022 14.6 0.0 7.3 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO70762.1 - 1.3e-06 28.6 5.6 1.8 8.9 0.0 6.2 5 1 0 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 CDO70762.1 - 1.5e-06 28.1 8.2 6.4e-05 22.8 2.3 4.8 3 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 CDO70762.1 - 1.8e-05 24.9 24.4 0.088 13.4 0.0 11.4 12 3 3 15 15 13 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDO70762.1 - 0.00094 18.6 1.6 1.9 8.2 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CDO70762.1 - 0.0024 17.6 8.6 2.5 7.8 0.3 5.6 4 2 2 6 6 6 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.12 CDO70762.1 - 0.0064 16.3 19.3 0.062 13.2 0.1 7.7 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO70762.1 - 0.0069 16.0 4.8 9 6.3 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDO70762.1 - 0.017 15.7 21.9 0.11 13.2 0.0 7.5 10 0 0 10 10 8 0 Tetratricopeptide repeat GST_C PF00043.20 CDO70762.1 - 0.017 15.0 0.3 0.064 13.2 0.2 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TPR_7 PF13176.1 CDO70762.1 - 0.023 14.4 7.5 2.4 8.1 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat PPTA PF01239.17 CDO70763.1 - 4e-24 82.8 14.7 1.2e-08 33.9 0.9 5.8 5 1 1 6 6 6 4 Protein prenyltransferase alpha subunit repeat Vps8 PF12816.2 CDO70763.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 Exonuc_VII_L PF02601.10 CDO70764.1 - 0.075 12.2 5.9 0.13 11.3 4.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dioxygenase_C PF00775.16 CDO70765.1 - 5.8e-56 188.6 0.0 8.8e-56 188.0 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 CDO70765.1 - 1.2e-19 70.0 0.1 1.4e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 CDO70765.1 - 0.029 14.4 0.1 0.19 11.7 0.0 2.3 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain Got1 PF04178.7 CDO70766.1 - 2.5e-13 50.1 20.5 5e-13 49.1 14.2 1.6 1 1 0 1 1 1 1 Got1/Sft2-like family Lactamase_B PF00753.22 CDO70767.1 - 1.7e-20 73.5 1.9 2.9e-20 72.7 1.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 CDO70767.1 - 2.4e-05 24.0 0.0 4.8e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 CDO70767.1 - 4.5e-05 23.0 0.2 6.1e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1191 PF06697.7 CDO70768.1 - 0.011 14.5 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF456 PF04306.8 CDO70768.1 - 0.029 14.4 0.3 0.06 13.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF456) EphA2_TM PF14575.1 CDO70768.1 - 0.098 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 CDO70768.1 - 0.1 10.8 0.0 0.14 10.3 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FAM176 PF14851.1 CDO70768.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 FAM176 family PDGLE PF13190.1 CDO70768.1 - 0.25 11.0 2.0 0.45 10.2 1.4 1.5 1 0 0 1 1 1 0 PDGLE domain Gly-zipper_YMGG PF13441.1 CDO70768.1 - 4.5 6.8 10.8 2.1 7.9 4.5 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper Piwi PF02171.12 CDO70771.1 - 4.1e-71 239.4 0.0 8.8e-71 238.3 0.0 1.6 2 0 0 2 2 2 1 Piwi domain DUF1785 PF08699.5 CDO70771.1 - 9.7e-16 56.8 0.0 2.4e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 CDO70771.1 - 1.4e-07 30.8 0.0 4.3e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 PAZ domain SRP54 PF00448.17 CDO70772.1 - 5.5e-46 156.4 0.2 2.5e-45 154.3 0.1 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 CDO70772.1 - 5.5e-43 147.3 0.3 2.7e-42 145.0 0.2 1.9 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 CDO70772.1 - 1.5e-07 31.4 0.1 5.8e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 CDO70772.1 - 2.4e-07 30.3 0.0 6.5e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CDO70772.1 - 9.8e-05 21.2 0.0 0.00023 20.0 0.0 1.6 1 0 0 1 1 1 1 ArgK protein AAA_22 PF13401.1 CDO70772.1 - 0.0014 18.7 0.0 0.01 15.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 CDO70772.1 - 0.006 16.3 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 CDO70772.1 - 0.006 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDO70772.1 - 0.02 14.9 0.2 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 CDO70772.1 - 0.047 13.1 0.1 0.66 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 CDO70772.1 - 0.051 13.2 0.0 0.16 11.6 0.0 1.8 1 1 0 1 1 1 0 NTPase ArsA_ATPase PF02374.10 CDO70772.1 - 0.072 12.1 0.7 2.9 6.8 0.0 2.3 1 1 1 2 2 2 0 Anion-transporting ATPase Fer4_NifH PF00142.13 CDO70772.1 - 0.083 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Img2 PF05046.9 CDO70774.1 - 6.4e-07 29.5 0.1 4.8e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial large subunit ribosomal protein (Img2) INT_SG_DDX_CT_C PF15300.1 CDO70774.1 - 0.04 13.3 0.0 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Glyco_hydro_43 PF04616.9 CDO70775.1 - 2.6e-15 56.2 3.7 4.1e-15 55.6 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_62 PF03664.8 CDO70775.1 - 0.0011 18.2 0.3 0.0031 16.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 62 SOR_SNZ PF01680.12 CDO70776.1 - 2.2e-113 376.9 5.6 3.4e-113 376.3 3.9 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 CDO70776.1 - 1.1e-10 41.0 2.5 2.7e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 CDO70776.1 - 6.2e-05 21.9 0.1 0.15 10.8 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 CDO70776.1 - 0.0036 16.3 0.2 0.084 11.8 0.0 2.3 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 CDO70776.1 - 0.0038 16.5 0.5 0.18 11.0 0.0 2.8 2 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 CDO70776.1 - 0.0055 15.8 5.1 0.016 14.3 0.1 2.4 2 1 0 2 2 2 1 Nitronate monooxygenase IGPS PF00218.16 CDO70776.1 - 0.0068 15.4 0.1 0.057 12.4 0.0 2.3 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase Cyclin_N PF00134.18 CDO70779.1 - 7.5e-10 38.4 0.0 2.4e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Ras PF00071.17 CDO70780.1 - 2.5e-65 218.7 1.5 3.2e-65 218.4 1.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO70780.1 - 7.5e-22 78.0 0.8 5.2e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CDO70780.1 - 2.6e-17 62.6 0.2 3.2e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO70780.1 - 5.1e-07 29.0 0.1 6.3e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDO70780.1 - 7.7e-06 25.4 0.3 1.6e-05 24.4 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CDO70780.1 - 9.6e-06 24.9 0.1 1.2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CDO70780.1 - 1.7e-05 24.7 0.3 4.3e-05 23.4 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CDO70780.1 - 0.00032 20.8 1.0 0.0021 18.1 0.0 2.3 1 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CDO70780.1 - 0.00035 19.8 0.6 0.053 12.6 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 CDO70780.1 - 0.0022 18.2 0.7 0.34 11.1 0.0 2.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 CDO70780.1 - 0.0061 15.8 0.1 0.036 13.3 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.1 CDO70780.1 - 0.012 15.1 1.2 0.083 12.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.9 CDO70780.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDO70780.1 - 0.027 14.4 2.0 0.068 13.1 0.1 2.4 1 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 CDO70780.1 - 0.038 13.9 0.2 0.21 11.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CDO70780.1 - 0.053 13.8 0.5 0.13 12.5 0.3 1.9 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 CDO70780.1 - 0.075 12.0 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 CDO70780.1 - 0.076 12.5 0.1 1.1 8.7 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation rve PF00665.21 CDO70780.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain RNA_helicase PF00910.17 CDO70780.1 - 0.55 10.4 2.5 1.2 9.3 0.1 2.6 2 1 0 2 2 2 0 RNA helicase Asp PF00026.18 CDO70781.1 - 1.4e-50 172.3 0.2 1.8e-50 172.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO70781.1 - 1e-06 28.7 1.1 2.1e-06 27.7 0.6 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO70781.1 - 0.00011 22.5 0.7 0.023 15.1 0.5 3.3 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO70781.1 - 1.2 9.0 4.3 0.83 9.5 0.1 2.5 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Zn_clus PF00172.13 CDO70783.1 - 8.5e-07 28.7 4.5 1.6e-06 27.8 3.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.5 CDO70784.1 - 1.1e-23 84.1 0.0 1.8e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Peripla_BP_1 PF00532.16 CDO70784.1 - 0.063 12.4 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family HAD_2 PF13419.1 CDO70785.1 - 4e-17 63.0 0.0 3.7e-12 46.8 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CDO70785.1 - 1.5e-05 24.6 0.0 6.9e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CDO70785.1 - 0.024 14.5 0.0 0.12 12.2 0.0 2.1 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 CDO70785.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase EF-hand_6 PF13405.1 CDO70786.1 - 4e-13 48.0 0.0 3.7e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CDO70786.1 - 7e-13 46.8 0.0 9.2e-06 24.6 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 CDO70786.1 - 1.3e-10 40.0 0.0 4.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CDO70786.1 - 8.3e-09 35.4 0.0 0.001 19.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CDO70786.1 - 5.3e-06 25.9 0.0 0.14 11.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 CDO70786.1 - 0.0016 18.2 0.0 0.54 10.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain AMP-binding PF00501.23 CDO70787.1 - 4.6e-40 137.2 0.0 5.7e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 CDO70788.1 - 3.2e-26 91.7 0.1 4.3e-26 91.2 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CDO70788.1 - 0.003 18.4 1.5 0.032 15.1 1.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mitofilin PF09731.4 CDO70788.1 - 0.014 14.0 0.1 0.019 13.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Adeno_PIX PF03955.9 CDO70788.1 - 0.082 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) MFS_1 PF07690.11 CDO70789.1 - 9.3e-29 100.2 30.1 9.3e-29 100.2 20.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PIG-Y PF15159.1 CDO70791.1 - 2.3e-05 24.4 0.5 0.0069 16.5 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y CLTH PF10607.4 CDO70792.1 - 7.1e-18 64.6 0.0 1.4e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 CDO70792.1 - 7.2e-18 64.0 1.2 1.6e-17 62.8 0.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 CDO70792.1 - 0.00022 20.5 1.3 0.00027 20.2 0.1 1.6 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_5 PF14634.1 CDO70792.1 - 0.0048 16.6 0.3 0.0085 15.7 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CDO70792.1 - 0.013 15.2 0.2 0.023 14.5 0.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CDO70792.1 - 0.025 14.5 0.8 0.044 13.8 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CDO70792.1 - 0.053 13.0 1.5 0.1 12.1 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 CDO70792.1 - 0.075 12.7 0.4 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ApoLp-III PF07464.6 CDO70792.1 - 0.095 12.7 0.8 0.2 11.6 0.5 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) zf-C3HC4 PF00097.20 CDO70792.1 - 0.11 12.1 0.8 0.2 11.3 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3328 PF11807.3 CDO70792.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF1090 PF06476.7 CDO70792.1 - 0.24 11.0 1.6 0.25 11.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) Pirin PF02678.11 CDO70794.1 - 3.8e-30 103.9 0.1 7.3e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 CDO70794.1 - 8.6e-28 96.4 0.0 2.9e-27 94.7 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 CDO70794.1 - 0.00021 20.7 0.6 0.062 12.8 0.4 2.7 2 0 0 2 2 2 2 Cupin domain AA_permease PF00324.16 CDO70795.1 - 1.9e-122 409.0 40.9 2.3e-122 408.7 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CDO70795.1 - 1.8e-33 115.7 44.5 2.6e-33 115.2 30.8 1.2 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 CDO70795.1 - 0.14 12.3 0.0 0.14 12.3 0.0 4.4 5 1 1 6 6 6 0 PrgI family protein ECH PF00378.15 CDO70796.1 - 1.1e-25 90.2 0.0 1.3e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Prenyltrans PF00432.16 CDO70797.1 - 4.2e-54 179.7 5.1 2.4e-12 46.1 0.0 7.1 7 0 0 7 7 7 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CDO70797.1 - 9.2e-30 103.3 0.0 2.2e-13 50.6 0.0 4.0 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CDO70797.1 - 3.5e-08 33.4 0.0 6.6e-06 26.1 0.0 3.1 2 1 1 3 3 3 1 Prenyltransferase-like Herpes_IR6 PF06307.7 CDO70797.1 - 0.15 11.3 0.0 0.83 8.9 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus IR6 protein HEAT_2 PF13646.1 CDO70798.1 - 0.014 15.6 6.4 0.045 14.0 0.4 4.0 3 1 0 3 3 3 0 HEAT repeats RWD PF05773.17 CDO70799.1 - 1.5e-19 69.9 0.1 1.5e-19 69.9 0.1 2.1 3 0 0 3 3 3 1 RWD domain DUF2422 PF10337.4 CDO70799.1 - 0.066 11.9 0.8 0.094 11.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) FAA_hydrolase_N PF09298.6 CDO70799.1 - 0.15 12.0 2.4 0.12 12.3 0.5 1.7 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal FinO_N PF12602.3 CDO70799.1 - 0.34 11.2 5.3 0.79 10.0 3.7 1.6 1 0 0 1 1 1 0 Fertility inhibition protein N terminal UPF0560 PF10577.4 CDO70799.1 - 0.4 8.8 4.4 0.51 8.5 3.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2895 PF11444.3 CDO70799.1 - 1 8.5 3.6 0.54 9.4 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2895) Ribosomal_S21 PF01165.15 CDO70800.1 - 1.6e-07 30.6 3.6 2.7e-07 29.9 2.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 DUF354 PF04007.7 CDO70800.1 - 0.0073 15.2 0.0 0.0085 15.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) Cyclin_N PF00134.18 CDO70802.1 - 4.3e-10 39.2 1.2 8.5e-10 38.2 0.3 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CDO70802.1 - 2.3e-05 24.2 0.7 0.12 12.3 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 CDO70802.1 - 8.4e-05 22.3 0.6 0.0046 16.7 0.2 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat IF-2B PF01008.12 CDO70803.1 - 4e-59 199.9 0.0 5.2e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family CLASP_N PF12348.3 CDO70805.1 - 1.1e-27 96.8 0.0 3e-07 30.0 0.0 5.4 5 0 0 5 5 5 4 CLASP N terminal HEAT_2 PF13646.1 CDO70805.1 - 1.9e-13 50.5 17.7 0.1 12.8 0.0 10.0 9 2 1 10 10 10 3 HEAT repeats HEAT PF02985.17 CDO70805.1 - 2.7e-13 48.7 17.2 1.6 9.0 0.0 12.3 13 0 0 13 13 13 3 HEAT repeat Adaptin_N PF01602.15 CDO70805.1 - 0.00022 19.6 0.7 2 6.6 0.1 4.7 6 0 0 6 6 6 2 Adaptin N terminal region HEAT_EZ PF13513.1 CDO70805.1 - 0.00054 20.3 9.8 12 6.4 0.0 7.3 6 1 1 7 7 7 1 HEAT-like repeat TAN PF11640.3 CDO70805.1 - 0.001 18.8 2.9 0.14 11.8 0.1 4.9 7 0 0 7 7 7 1 Telomere-length maintenance and DNA damage repair Cnd1 PF12717.2 CDO70805.1 - 0.042 13.6 0.0 56 3.5 0.0 4.9 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 CDO70805.1 - 0.047 13.5 0.0 2.3 8.1 0.0 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) SapB_2 PF03489.12 CDO70805.1 - 0.55 10.3 0.6 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 2 Acyltransferase PF01553.16 CDO70806.1 - 1.9e-11 43.5 0.0 4.1e-10 39.1 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Peptidase_M24 PF00557.19 CDO70807.1 - 2.2e-40 138.4 0.0 3e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 FAD_binding_3 PF01494.14 CDO70808.1 - 5.5e-22 78.3 0.5 1.2e-13 50.8 0.0 3.1 2 1 1 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.7 CDO70808.1 - 0.043 12.7 0.0 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein SE PF08491.5 CDO70808.1 - 0.048 12.4 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Apc5 PF12862.2 CDO70809.1 - 3.1e-08 33.3 0.1 5.1e-07 29.4 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 CDO70809.1 - 0.0098 15.8 2.0 0.95 9.4 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat HNH_2 PF13391.1 CDO70811.1 - 2.3e-05 24.0 0.4 5.9e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 HNH endonuclease FAD-oxidase_C PF02913.14 CDO70812.1 - 6.8e-58 195.9 0.0 1e-57 195.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CDO70812.1 - 1.9e-25 88.9 0.0 3.8e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain RRM_1 PF00076.17 CDO70812.1 - 0.061 12.9 0.1 2.4 7.8 0.0 3.2 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PQ-loop PF04193.9 CDO70813.1 - 8.1e-12 44.5 0.9 1.6e-11 43.5 0.6 1.5 1 0 0 1 1 1 1 PQ loop repeat eIF3_N PF09440.5 CDO70814.1 - 6.9e-45 152.4 5.2 3.1e-44 150.3 1.8 2.6 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 CDO70814.1 - 3.6e-09 36.8 0.0 8.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 CDO70814.1 - 0.007 16.1 0.4 0.07 12.9 0.1 2.5 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 PARP_reg PF02877.9 CDO70814.1 - 0.044 13.4 0.3 0.094 12.3 0.2 1.6 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain HECT PF00632.20 CDO70815.1 - 1.7e-96 323.1 0.0 2.4e-96 322.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 CDO70815.1 - 0.0055 16.2 0.9 0.021 14.4 0.6 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Asp PF00026.18 CDO70820.1 - 0.021 14.0 0.0 0.097 11.9 0.0 1.8 1 1 1 2 2 2 0 Eukaryotic aspartyl protease Mit_KHE1 PF10173.4 CDO70821.1 - 2.5e-31 108.9 0.0 3.8e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Pro-kuma_activ PF09286.6 CDO70822.1 - 4.1e-33 114.4 0.0 2.4e-32 111.9 0.0 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain mRNA_triPase PF02940.10 CDO70823.1 - 3.9e-48 164.0 0.0 5e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Fic PF02661.13 CDO70824.1 - 1.3e-14 54.6 0.1 3.9e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Fic/DOC family E1_dh PF00676.15 CDO70825.1 - 1.3e-83 280.2 0.0 1.5e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Spuma_A9PTase PF03539.9 CDO70825.1 - 0.18 11.7 1.0 0.34 10.7 0.7 1.4 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Myb_DNA-bind_6 PF13921.1 CDO70825.1 - 3.2 7.9 6.6 4 7.6 1.1 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain Syndecan PF01034.15 CDO70826.1 - 0.00052 19.6 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 Syndecan domain CD34_antigen PF06365.7 CDO70826.1 - 0.094 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Fe-ADH PF00465.14 CDO70828.1 - 6.8e-56 189.4 0.2 1.1e-55 188.8 0.1 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CDO70828.1 - 1e-37 129.8 0.0 1.2e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 CDO70828.1 - 8.2e-08 31.4 0.4 1.5e-06 27.3 0.3 2.2 1 1 0 1 1 1 1 3-dehydroquinate synthase Peptidase_S3 PF00944.14 CDO70828.1 - 0.049 13.0 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Alphavirus core protein MatE PF01554.13 CDO70829.1 - 7.8e-47 158.9 17.7 5.6e-25 87.8 4.0 2.4 2 0 0 2 2 2 2 MatE Arginase PF00491.16 CDO70830.1 - 3.8e-79 265.8 0.1 5e-79 265.4 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 CDO70830.1 - 0.026 14.7 0.1 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 UPF0489 domain SKG6 PF08693.5 CDO70831.1 - 5.9e-05 22.3 0.1 0.00033 19.8 0.1 2.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rick_17kDa_Anti PF05433.10 CDO70831.1 - 0.0028 17.2 4.6 0.0051 16.4 3.2 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF1191 PF06697.7 CDO70831.1 - 0.0054 15.5 0.0 0.0077 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Gly-zipper_Omp PF13488.1 CDO70831.1 - 0.0064 16.1 6.5 0.012 15.2 4.5 1.5 1 0 0 1 1 1 1 Glycine zipper Yip1 PF04893.12 CDO70831.1 - 0.0094 15.4 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 1 Yip1 domain Syndecan PF01034.15 CDO70831.1 - 0.025 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain DUF456 PF04306.8 CDO70831.1 - 0.034 14.1 0.2 0.048 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.1 CDO70831.1 - 0.035 13.6 5.1 0.065 12.7 3.5 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Adeno_E3_CR2 PF02439.10 CDO70831.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gly-zipper_OmpA PF13436.1 CDO70831.1 - 3.5 7.3 8.4 11 5.6 5.8 2.0 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Mid2 PF04478.7 CDO70833.1 - 0.001 18.5 0.2 0.0053 16.1 0.1 2.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor MMS1_N PF10433.4 CDO70836.1 - 5.3e-17 61.1 0.0 1.4e-11 43.2 0.0 2.1 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term C2 PF00168.25 CDO70837.1 - 7.5e-09 35.3 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain SR-25 PF10500.4 CDO70837.1 - 0.011 15.1 16.8 0.025 14.0 11.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ndc1_Nup PF09531.5 CDO70837.1 - 0.47 8.8 2.6 0.67 8.3 1.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.17 CDO70839.1 - 3.3e-31 108.4 4.8 5.9e-31 107.6 3.3 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter BRI3BP PF14965.1 CDO70839.1 - 0.037 13.4 0.6 0.081 12.2 0.4 1.5 1 0 0 1 1 1 0 Negative regulator of p53/TP53 SKN1 PF03935.10 CDO70840.1 - 6.3e-202 671.1 5.1 7.7e-202 670.8 3.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Peptidase_C48 PF02902.14 CDO70841.1 - 6.8e-35 120.6 0.1 6.1e-23 81.5 0.0 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Glyco_trans_2_3 PF13632.1 CDO70842.1 - 3.4e-15 56.2 2.4 3.4e-15 56.2 1.7 3.5 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CDO70842.1 - 6.4e-14 52.2 0.2 1.7e-11 44.4 0.2 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 CDO70842.1 - 7.6e-08 31.1 0.0 5.2e-07 28.4 0.0 2.0 1 1 0 1 1 1 1 Chitin synthase Glyco_transf_21 PF13506.1 CDO70842.1 - 0.00015 21.1 0.5 0.019 14.2 0.1 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CDO70842.1 - 0.0017 18.0 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Rad51 PF08423.6 CDO70842.1 - 0.34 9.7 0.0 0.57 9.0 0.0 1.2 1 0 0 1 1 1 0 Rad51 F-box PF00646.28 CDO70843.1 - 4.3e-08 32.6 0.3 1e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO70843.1 - 6.6e-05 22.5 0.3 0.00016 21.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like FAD_binding_2 PF00890.19 CDO70844.1 - 1.4e-44 152.6 1.9 9.2e-38 130.1 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 CDO70844.1 - 2.9e-08 33.2 0.1 4.2e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.19 CDO70844.1 - 1.3e-06 27.5 2.9 2.3e-05 23.4 2.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CDO70844.1 - 0.00012 22.0 0.0 0.0077 16.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CDO70844.1 - 0.00058 18.8 3.1 0.00079 18.3 0.2 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CDO70844.1 - 0.0031 17.6 0.0 0.0077 16.3 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO70844.1 - 0.0032 17.4 2.5 0.0034 17.3 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CDO70844.1 - 0.008 14.6 0.0 0.22 9.9 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein adh_short_C2 PF13561.1 CDO70845.1 - 2.3e-22 79.9 0.3 7.2e-21 75.0 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO70845.1 - 1.3e-20 73.9 4.1 4.6e-15 55.9 0.2 2.5 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 CDO70845.1 - 3.2e-08 33.4 1.3 9.7e-08 31.8 0.2 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CDO70845.1 - 0.0022 17.4 0.3 0.011 15.2 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO70845.1 - 0.0024 17.8 0.6 0.015 15.2 0.2 2.3 2 1 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 CDO70845.1 - 0.024 14.7 0.1 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CDO70845.1 - 0.027 14.1 1.3 0.061 12.9 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 CDO70845.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 CDO70845.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding F-box-like PF12937.2 CDO70846.1 - 3.1e-10 39.6 0.1 8.4e-10 38.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.2 CDO70847.1 - 0.0026 17.6 0.4 0.0035 17.2 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family CobU PF02283.11 CDO70847.1 - 0.076 12.4 0.4 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Abhydrolase_6 PF12697.2 CDO70848.1 - 2.1e-13 50.7 2.7 3.5e-13 49.9 1.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO70848.1 - 0.00046 19.9 0.0 0.0011 18.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO70848.1 - 0.027 14.2 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase MATH PF00917.21 CDO70849.1 - 3.4e-05 24.0 0.1 6.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 MATH domain GRASP55_65 PF04495.9 CDO70850.1 - 6.6e-59 197.8 0.0 1.3e-41 141.7 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 CDO70850.1 - 0.0012 18.6 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PPR_3 PF13812.1 CDO70851.1 - 0.0038 17.3 0.1 1.9 8.9 0.0 4.5 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 CDO70851.1 - 0.03 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family Fungal_trans PF04082.13 CDO70852.1 - 3.7e-05 22.7 0.1 7.5e-05 21.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ThiF PF00899.16 CDO70853.1 - 2.2e-12 46.9 0.0 8e-06 25.7 0.1 2.4 2 0 0 2 2 2 2 ThiF family MetJ PF01340.15 CDO70853.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Met Apo-repressor, MetJ Mur_ligase_M PF08245.7 CDO70854.1 - 3.2e-08 33.8 0.0 6.6e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CDO70854.1 - 0.006 16.5 0.0 0.028 14.4 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain VWA_2 PF13519.1 CDO70854.1 - 0.065 13.3 0.0 0.4 10.7 0.0 2.2 2 1 0 2 2 2 0 von Willebrand factor type A domain RRM_1 PF00076.17 CDO70855.1 - 9.8e-52 172.4 2.2 1.2e-18 66.5 0.1 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO70855.1 - 2.7e-46 155.4 0.1 5.6e-18 64.6 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO70855.1 - 1.1e-24 86.0 0.1 1e-09 38.0 0.0 4.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO70855.1 - 7e-05 22.5 0.0 0.29 10.9 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Suf PF05843.9 CDO70855.1 - 0.00014 21.6 0.3 0.0051 16.5 0.0 3.0 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) RRM_3 PF08777.6 CDO70855.1 - 0.0095 15.7 5.7 0.36 10.7 0.1 4.4 4 0 0 4 4 4 1 RNA binding motif TPR_14 PF13428.1 CDO70855.1 - 2.3 9.1 0.0 2.3 9.1 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF3149 PF11346.3 CDO70856.1 - 0.66 9.5 2.1 1.1 8.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) VirB8 PF04335.8 CDO70856.1 - 4.6 6.7 5.9 0.55 9.7 0.4 2.1 2 1 0 2 2 2 0 VirB8 protein AAA_23 PF13476.1 CDO70857.1 - 5.3e-12 46.5 25.9 5.3e-12 46.5 18.0 5.1 3 2 0 3 3 1 1 AAA domain SMC_N PF02463.14 CDO70857.1 - 2.8e-11 43.0 9.9 2.8e-11 43.0 6.9 3.6 2 2 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CDO70857.1 - 2.3e-07 30.2 6.2 7e-06 25.3 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CDO70857.1 - 0.0001 21.7 0.1 0.00059 19.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CDO70857.1 - 0.0021 18.0 1.4 0.0031 17.5 0.0 2.1 3 0 0 3 3 3 1 AAA domain Seryl_tRNA_N PF02403.17 CDO70857.1 - 0.003 17.5 2.1 0.003 17.5 1.4 7.6 3 2 3 6 6 6 1 Seryl-tRNA synthetase N-terminal domain DUF258 PF03193.11 CDO70857.1 - 0.0097 15.1 0.1 0.45 9.6 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Reo_sigmaC PF04582.7 CDO70857.1 - 0.021 14.0 17.0 4.3 6.4 0.0 4.6 3 1 1 4 4 4 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 CDO70857.1 - 0.094 13.0 0.0 0.094 13.0 0.0 4.0 3 2 0 3 3 1 0 ABC transporter Filament PF00038.16 CDO70857.1 - 1.2 8.5 80.5 0.0074 15.7 12.3 4.7 2 2 2 4 4 3 0 Intermediate filament protein DUF948 PF06103.6 CDO70857.1 - 5.2 7.0 18.8 2 8.3 1.5 4.9 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) ICL PF00463.16 CDO70858.1 - 2e-251 834.7 0.3 2.3e-251 834.6 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CDO70858.1 - 7.7e-10 38.3 0.0 1.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Glycos_transf_4 PF00953.16 CDO70859.1 - 2.3e-18 66.5 2.0 4e-18 65.7 1.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 4 F-actin_cap_A PF01267.12 CDO70860.1 - 1.3e-88 296.5 0.0 1.6e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F_actin_cap_B PF01115.12 CDO70860.1 - 0.031 13.4 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 F-actin capping protein, beta subunit AMP-binding PF00501.23 CDO70861.1 - 1.6e-46 158.5 0.0 2e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ATP_transf PF09830.4 CDO70861.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 ATP adenylyltransferase AMP-binding PF00501.23 CDO70862.1 - 8.6e-05 21.1 0.0 0.00012 20.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme SET PF00856.23 CDO70863.1 - 1.3e-09 38.5 0.1 9.6e-06 25.9 0.0 2.4 1 1 1 2 2 2 2 SET domain dCMP_cyt_deam_1 PF00383.17 CDO70863.1 - 2e-05 24.1 0.4 0.00012 21.6 0.2 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region TilS PF09179.6 CDO70863.1 - 0.00051 20.0 0.1 0.0019 18.1 0.1 1.9 2 0 0 2 2 2 1 TilS substrate binding domain PLDc_2 PF13091.1 CDO70864.1 - 5.3e-12 45.5 0.0 2e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CDO70864.1 - 8.2e-10 38.1 1.2 0.00026 20.6 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.19 CDO70864.1 - 3.2e-09 36.5 0.1 1.2e-07 31.4 0.0 3.0 2 0 0 2 2 2 1 PX domain PH PF00169.24 CDO70864.1 - 0.0015 18.6 0.9 0.015 15.5 0.6 2.3 1 1 0 1 1 1 1 PH domain PROCN PF08083.6 CDO70865.1 - 1.8e-218 724.9 8.2 5.7e-218 723.3 5.5 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CDO70865.1 - 6.9e-128 424.7 0.5 1.2e-127 423.9 0.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CDO70865.1 - 2.1e-92 306.7 1.2 5.6e-92 305.3 0.8 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CDO70865.1 - 5.8e-80 266.2 2.2 5.8e-80 266.2 1.5 2.6 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CDO70865.1 - 2e-69 231.4 0.1 3.8e-69 230.5 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 CDO70865.1 - 1.5e-43 146.5 0.2 3.6e-43 145.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 CDO70865.1 - 7.6e-37 125.8 0.0 1.9e-36 124.5 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 CDO70865.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Corona_nucleoca PF00937.13 CDO70866.1 - 0.9 8.4 7.5 1.8 7.4 5.2 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Ubie_methyltran PF01209.13 CDO70868.1 - 4.2e-78 261.6 0.0 5.2e-78 261.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CDO70868.1 - 1.5e-13 50.5 0.0 2.6e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO70868.1 - 2.5e-12 46.7 0.0 4.1e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO70868.1 - 1.7e-11 44.4 0.0 3.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO70868.1 - 4.7e-11 42.9 0.0 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO70868.1 - 3.5e-10 40.2 0.0 8.5e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO70868.1 - 4e-07 30.5 0.0 9.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO70868.1 - 0.0027 17.7 0.0 0.011 15.7 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 CDO70868.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Hypothetical methyltransferase Tautomerase PF01361.16 CDO70868.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme ECH PF00378.15 CDO70869.1 - 1.7e-23 83.0 0.0 2.2e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CDO70869.1 - 0.00021 21.1 0.0 0.3 10.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S49 Asp PF00026.18 CDO70870.1 - 3.2e-67 227.0 2.2 3.8e-67 226.7 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO70870.1 - 2.3e-05 24.3 0.1 5.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal UMP1 PF05348.6 CDO70870.1 - 0.072 13.0 0.2 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 TAXi_C PF14541.1 CDO70870.1 - 0.11 12.0 0.1 0.76 9.3 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Pkinase PF00069.20 CDO70871.1 - 6.1e-58 195.9 0.0 9e-58 195.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70871.1 - 1.3e-18 66.9 0.0 6.8e-18 64.6 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 CDO70871.1 - 0.0046 16.3 0.7 0.017 14.4 0.1 2.2 2 1 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 CDO70871.1 - 0.065 12.1 0.8 2.9 6.7 0.0 2.5 3 0 0 3 3 3 0 Kinase-like Pox_ser-thr_kin PF05445.6 CDO70871.1 - 0.13 10.9 0.1 0.23 10.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MOZ_SAS PF01853.13 CDO70872.1 - 4.7e-77 257.4 0.0 6.9e-77 256.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 CDO70872.1 - 5.4e-17 61.2 22.2 2.6e-09 36.6 4.1 3.2 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 CDO70872.1 - 0.00034 19.8 13.3 0.0099 15.1 1.0 3.6 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 CDO70872.1 - 1.4 8.7 15.1 6.7 6.5 0.3 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 CDO70872.1 - 9.9 5.4 13.0 5.8 6.1 1.4 3.2 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain GFA PF04828.9 CDO70874.1 - 1e-11 44.6 1.1 2e-11 43.6 0.7 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-LSD1 PF06943.7 CDO70874.1 - 0.24 11.0 5.8 0.15 11.6 0.4 2.8 3 0 0 3 3 3 0 LSD1 zinc finger Antimicrobial_4 PF08024.6 CDO70875.1 - 0.15 11.9 0.3 0.31 10.9 0.2 1.6 1 0 0 1 1 1 0 Ant antimicrobial peptide ART PF01129.13 CDO70876.1 - 0.013 14.6 0.1 0.023 13.7 0.0 1.5 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase Urease_alpha PF00449.15 CDO70878.1 - 5.9e-55 184.5 2.5 1.2e-54 183.5 1.7 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_1 PF01979.15 CDO70878.1 - 9.9e-44 150.3 1.2 4.2e-40 138.4 0.2 2.2 1 1 1 2 2 2 2 Amidohydrolase family Urease_beta PF00699.15 CDO70878.1 - 5.3e-42 141.7 0.2 1.4e-41 140.3 0.1 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 CDO70878.1 - 1.9e-38 130.4 0.4 5e-38 129.1 0.1 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_5 PF13594.1 CDO70878.1 - 2.3e-06 27.3 0.7 6.5e-06 25.8 0.5 1.8 1 0 0 1 1 1 1 Amidohydrolase EVC2_like PF12297.3 CDO70878.1 - 0.23 10.0 0.9 0.35 9.4 0.6 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Thaumatin PF00314.12 CDO70879.1 - 5.7e-52 176.2 9.1 2e-50 171.2 6.3 2.5 1 1 0 1 1 1 1 Thaumatin family MFS_1 PF07690.11 CDO70881.1 - 4.4e-40 137.4 53.4 5.6e-32 110.8 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDO70881.1 - 4.5e-07 28.6 22.8 1.9e-05 23.2 7.7 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 CDO70881.1 - 0.24 9.5 8.7 0.056 11.6 0.3 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) BBE PF08031.7 CDO70883.1 - 2.7e-07 30.4 0.1 4.3e-07 29.7 0.0 1.4 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.18 CDO70884.1 - 1.7e-05 24.2 2.3 0.00072 19.0 0.0 2.8 2 1 1 3 3 3 2 FAD binding domain SPT2 PF08243.6 CDO70885.1 - 1.4e-14 54.3 12.8 1.4e-14 54.3 8.9 4.3 4 1 1 5 5 5 1 SPT2 chromatin protein Spore_coat_CotO PF14153.1 CDO70885.1 - 0.23 10.8 21.6 0.013 14.9 5.7 2.4 2 0 0 2 2 2 0 Spore coat protein CotO Ycf1 PF05758.7 CDO70885.1 - 9.2 3.8 13.4 1.1 6.8 4.8 2.0 2 0 0 2 2 2 0 Ycf1 Med3 PF11593.3 CDO70885.1 - 9.6 5.3 18.3 16 4.5 12.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRM_6 PF14259.1 CDO70886.1 - 5.8e-06 26.1 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO70886.1 - 0.00016 21.2 0.0 0.00037 20.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO70886.1 - 0.014 15.1 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acyl-CoA_dh_1 PF00441.19 CDO70887.1 - 4.7e-33 114.4 0.6 6.8e-33 113.8 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CDO70887.1 - 2.3e-17 62.2 1.0 6.7e-17 60.7 0.2 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CDO70887.1 - 4.2e-12 46.6 0.0 8.7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 CDO70887.1 - 7.7e-12 44.8 0.0 2e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 CDO70887.1 - 8e-06 26.1 0.1 1.4e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Tn916-Xis PF09035.5 CDO70887.1 - 0.14 12.2 0.0 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 Excisionase from transposon Tn916 SPA PF08616.5 CDO70888.1 - 0.00014 21.5 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis TOM13 PF08219.6 CDO70889.1 - 9.9e-14 50.8 0.0 3.1e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Outer membrane protein TOM13 Vps39_1 PF10366.4 CDO70890.1 - 3.6e-25 88.0 0.0 8e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 CDO70890.1 - 2e-12 46.9 1.3 1.2e-07 31.3 0.2 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.4 CDO70890.1 - 3.5e-10 40.0 0.3 7.1e-10 39.0 0.2 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 CDO70890.1 - 2.9e-05 23.6 0.0 5.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 CNH domain TPR_11 PF13414.1 CDO70890.1 - 0.43 10.2 7.7 17 5.1 0.0 4.2 3 1 0 4 4 4 0 TPR repeat TPR_1 PF00515.23 CDO70890.1 - 3.6 7.3 10.0 13 5.5 0.8 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDO70890.1 - 5.8 6.9 6.1 18 5.4 0.3 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CDO70890.1 - 6.1 7.0 11.5 15 5.7 0.9 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat Ank_4 PF13637.1 CDO70892.1 - 9.4e-23 80.1 11.0 0.00025 21.4 0.2 5.9 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDO70892.1 - 1.2e-21 76.2 16.2 9.1e-07 28.9 0.0 5.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 CDO70892.1 - 1.8e-19 69.8 8.8 2.1e-06 28.0 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 CDO70892.1 - 1.8e-16 59.0 11.0 0.0028 17.3 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 CDO70892.1 - 4.8e-12 44.8 8.5 0.023 14.9 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat DUF1168 PF06658.7 CDO70893.1 - 0.92 9.0 11.2 1 8.8 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Spore_coat_CotO PF14153.1 CDO70893.1 - 2.5 7.5 13.2 2.7 7.4 9.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 CDO70893.1 - 4.9 5.5 11.8 5.4 5.3 8.2 1.1 1 0 0 1 1 1 0 Daxx Family Methyltransf_25 PF13649.1 CDO70894.1 - 5.2e-07 29.9 0.1 2.8e-06 27.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO70894.1 - 4.6e-06 26.4 0.0 6.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO70894.1 - 0.0019 18.7 0.0 0.0033 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AMP_N PF05195.11 CDO70894.1 - 0.0079 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Methyltransf_11 PF08241.7 CDO70894.1 - 0.045 14.2 0.0 0.36 11.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 CDO70895.1 - 4.4e-06 26.9 0.0 2.1e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO70895.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CS PF04969.11 CDO70896.1 - 3e-08 34.0 0.2 5.9e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 CS domain Fork_head_N PF08430.7 CDO70896.1 - 2 8.8 10.1 3 8.2 7.0 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region BC10 PF06726.7 CDO70897.1 - 2.9e-05 23.9 12.4 4.8e-05 23.2 8.6 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Transposase_28 PF04195.7 CDO70897.1 - 0.037 13.3 0.4 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Putative gypsy type transposon WD40 PF00400.27 CDO70898.1 - 4.4e-46 153.1 1.0 2.2e-10 40.0 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CDO70898.1 - 3.5e-10 38.6 0.4 0.0012 17.0 0.0 4.2 3 1 0 4 4 4 4 Nucleoporin Nup120/160 DUF972 PF06156.8 CDO70898.1 - 0.11 12.8 0.5 0.25 11.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 CDO70898.1 - 0.45 9.5 5.2 0.76 8.7 3.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1664 PF07889.7 CDO70898.1 - 2 8.2 3.7 3.9 7.3 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 CDO70898.1 - 4.5 6.8 6.7 8.7 5.8 4.6 1.4 1 0 0 1 1 1 0 IncA protein Glyco_transf_49 PF13896.1 CDO70899.1 - 1.1e-28 100.2 0.0 1.6e-27 96.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan ATP11 PF06644.6 CDO70900.1 - 2.3e-70 237.1 0.0 2.6e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein CAGE1 PF15066.1 CDO70900.1 - 0.23 9.8 4.1 0.34 9.3 2.9 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family RHH_1 PF01402.16 CDO70900.1 - 1.4 8.8 4.4 0.39 10.6 0.3 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family NAD_binding_10 PF13460.1 CDO70901.1 - 1.2e-24 87.3 0.1 1.4e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CDO70901.1 - 2.2e-10 40.2 0.0 3.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CDO70901.1 - 2.8e-05 23.6 0.0 4.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO70901.1 - 4.3e-05 22.3 0.0 0.00055 18.7 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 CDO70901.1 - 0.0073 16.7 0.1 0.054 13.9 0.0 2.5 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 CDO70901.1 - 0.036 12.9 0.0 4.1 6.2 0.0 2.1 1 1 0 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.19 CDO70901.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_16 PF00722.16 CDO70902.1 - 3.4e-06 26.4 0.0 9.9e-06 24.9 0.0 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Band_7_1 PF13421.1 CDO70902.1 - 0.076 12.5 0.1 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 SPFH domain-Band 7 family BPL_LplA_LipB PF03099.14 CDO70903.1 - 1.7e-08 34.5 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Thiolase_C PF02803.13 CDO70904.1 - 7.6e-07 28.5 0.1 3e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 CDO70904.1 - 1e-05 24.6 0.0 4.5e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 CDO70904.1 - 5.3e-05 22.8 0.1 0.00061 19.3 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 CDO70904.1 - 0.1 12.0 0.2 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Shisa PF13908.1 CDO70906.1 - 0.046 13.8 0.2 0.046 13.8 0.2 3.2 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator CD34_antigen PF06365.7 CDO70906.1 - 0.059 13.0 0.2 0.18 11.4 0.1 1.7 2 0 0 2 2 2 0 CD34/Podocalyxin family Muted PF14942.1 CDO70907.1 - 0.031 14.1 0.6 0.034 14.0 0.4 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF2580 PF10824.3 CDO70907.1 - 0.065 13.5 4.0 0.1 12.9 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) DUF883 PF05957.8 CDO70907.1 - 0.11 12.9 7.3 0.67 10.3 4.9 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Laminin_II PF06009.7 CDO70907.1 - 0.21 11.3 4.1 0.3 10.8 2.8 1.3 1 0 0 1 1 1 0 Laminin Domain II LEA_4 PF02987.11 CDO70907.1 - 0.42 10.5 13.1 0.6 10.0 3.9 2.3 1 1 1 2 2 2 0 Late embryogenesis abundant protein YtxH PF12732.2 CDO70907.1 - 0.44 10.9 9.7 2.8 8.3 6.7 2.1 1 1 0 1 1 1 0 YtxH-like protein DUF3332 PF11810.3 CDO70907.1 - 0.55 9.8 2.7 0.67 9.6 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) DUF809 PF05663.6 CDO70907.1 - 2.8 7.8 5.7 4.2 7.2 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF809) DUF4118 PF13493.1 CDO70908.1 - 0.021 14.9 0.9 0.021 14.9 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) ORC6 PF05460.8 CDO70909.1 - 0.075 12.1 8.5 0.1 11.6 5.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) p450 PF00067.17 CDO70910.1 - 1.9e-59 201.4 0.0 2.2e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bacillus_HBL PF05791.6 CDO70911.1 - 0.24 10.7 1.1 15 4.8 0.1 2.8 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Peptidase_C14 PF00656.17 CDO70911.1 - 1.2 8.7 3.7 2.6 7.6 0.6 2.2 1 1 1 2 2 2 0 Caspase domain Utp12 PF04003.7 CDO70912.1 - 2.5e-13 49.8 0.9 8.3e-13 48.2 0.7 1.8 1 1 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 CDO70912.1 - 2.5e-08 33.4 9.8 2.7e-06 27.0 0.0 4.4 3 1 0 3 3 3 2 WD domain, G-beta repeat UTP15_C PF09384.5 CDO70912.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 UTP15 C terminal Proteasome_A_N PF10584.4 CDO70912.1 - 0.66 9.3 2.4 0.6 9.4 0.5 2.0 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Pkinase PF00069.20 CDO70913.1 - 4.9e-76 255.3 0.0 7.7e-76 254.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO70913.1 - 1.6e-36 125.7 0.0 3e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO70913.1 - 0.00078 18.4 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO70913.1 - 0.039 13.6 8.6 0.32 10.7 0.0 2.6 3 1 0 3 3 3 0 Phosphotransferase enzyme family H2TH PF06831.9 CDO70914.1 - 1.6e-22 79.0 0.0 1.2e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 CDO70914.1 - 3.8e-14 53.0 0.3 2e-13 50.7 0.2 2.1 1 1 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.6 CDO70914.1 - 0.00092 17.8 0.0 0.0017 17.0 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) ORF6N PF10543.4 CDO70914.1 - 0.03 14.3 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 ORF6N domain DUF3412 PF11892.3 CDO70915.1 - 0.36 10.6 0.1 5.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3412) Thiol-ester_cl PF10569.4 CDO70915.1 - 1.5 8.0 3.7 20 4.5 0.2 2.5 2 0 0 2 2 2 0 Alpha-macro-globulin thiol-ester bond-forming region SprT-like PF10263.4 CDO70916.1 - 2e-41 141.2 0.9 4.1e-41 140.2 0.6 1.5 1 0 0 1 1 1 1 SprT-like family Glyco_hydro_16 PF00722.16 CDO70917.1 - 1.4e-07 30.9 0.7 2.2e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 KAR9 PF08580.5 CDO70917.1 - 4 5.5 4.5 5.1 5.2 3.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Arm PF00514.18 CDO70918.1 - 1.8e-67 221.0 29.5 3.7e-13 48.7 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDO70918.1 - 2e-24 85.6 10.3 2.9e-07 30.6 0.1 7.8 1 1 6 8 8 8 8 HEAT repeats HEAT PF02985.17 CDO70918.1 - 2e-19 67.8 16.3 0.013 15.5 0.0 10.2 10 0 0 10 10 9 5 HEAT repeat HEAT_EZ PF13513.1 CDO70918.1 - 4.7e-16 58.7 10.8 0.092 13.2 0.2 8.5 6 2 3 9 9 9 5 HEAT-like repeat Arm_2 PF04826.8 CDO70918.1 - 2e-11 43.4 7.8 0.0018 17.4 0.5 3.7 2 1 1 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 CDO70918.1 - 1.5e-09 36.7 11.4 2.5e-05 22.8 0.1 3.0 2 1 1 3 3 3 2 Adaptin N terminal region KAP PF05804.7 CDO70918.1 - 1.2e-08 33.4 1.1 2.9e-08 32.1 0.5 1.7 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 CDO70918.1 - 2.5e-08 33.4 4.1 0.0018 17.4 2.0 4.4 2 1 1 3 3 3 2 V-ATPase subunit H IBN_N PF03810.14 CDO70918.1 - 0.0033 17.2 3.0 0.91 9.4 0.1 3.4 3 0 0 3 3 3 2 Importin-beta N-terminal domain V-ATPase_H_C PF11698.3 CDO70918.1 - 0.0037 17.1 3.2 9.3 6.1 0.1 4.4 2 1 1 4 4 4 1 V-ATPase subunit H DUF2454 PF10521.4 CDO70918.1 - 0.0066 15.4 1.1 0.17 10.8 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2454) Vac14_Fab1_bd PF12755.2 CDO70918.1 - 0.011 16.0 0.1 1.4 9.3 0.0 3.2 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 CDO70918.1 - 0.064 13.7 11.4 48 4.8 0.1 7.2 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat DUF3361 PF11841.3 CDO70918.1 - 0.12 12.0 6.7 0.47 10.1 0.6 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) Abhydrolase_2 PF02230.11 CDO70919.1 - 9e-41 139.6 0.0 8.4e-35 120.1 0.0 2.0 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CDO70919.1 - 4.3e-08 33.0 0.0 6.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO70919.1 - 2.6e-07 30.7 0.9 1.2e-05 25.3 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 CDO70919.1 - 0.0013 17.9 0.0 0.019 14.2 0.0 2.4 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Esterase_phd PF10503.4 CDO70919.1 - 0.0014 17.8 0.0 0.0029 16.9 0.0 1.4 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 CDO70919.1 - 0.0064 16.0 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PolyA_pol PF01743.15 CDO70920.1 - 1.2e-24 86.8 0.1 2.1e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CDO70920.1 - 0.00032 20.2 0.1 0.0014 18.1 0.0 2.2 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 CDO70920.1 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative HMG_box PF00505.14 CDO70921.1 - 5e-15 55.5 0.9 9.1e-15 54.6 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO70921.1 - 5.5e-05 23.4 0.3 9.5e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 HMG-box domain Toxin_54 PF15533.1 CDO70921.1 - 0.055 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Putative toxin 54 DUF2582 PF10771.4 CDO70921.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2582) DEAD PF00270.24 CDO70922.1 - 1.1e-37 129.1 0.1 1.8e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO70922.1 - 4.3e-24 84.1 0.1 1e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CDO70922.1 - 3.1e-05 22.9 0.0 5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CDO70922.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.14 CDO70922.1 - 0.013 15.8 0.6 0.013 15.8 0.4 2.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF1253 PF06862.7 CDO70922.1 - 0.11 10.8 0.0 1.1 7.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Mito_carr PF00153.22 CDO70923.1 - 2.5e-32 110.4 0.0 1.5e-18 66.2 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DEAD PF00270.24 CDO70924.1 - 3.4e-29 101.4 0.0 4.3e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDO70924.1 - 0.0004 20.2 0.0 0.00064 19.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CDO70925.1 - 1.8e-24 85.3 0.0 4.4e-24 84.1 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HATPase_c PF02518.21 CDO70926.1 - 4.8e-28 97.0 0.1 9.2e-28 96.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CDO70926.1 - 8.3e-21 74.0 0.0 6.6e-19 67.9 0.0 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 CDO70926.1 - 3.3e-17 62.2 0.1 1.3e-15 57.1 0.0 3.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 CDO70926.1 - 1.3e-14 54.5 2.9 3.5e-14 53.2 0.4 2.7 3 0 0 3 3 3 1 AAA ATPase domain GAF_2 PF13185.1 CDO70926.1 - 2.3e-11 44.3 0.0 7.4e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 CDO70926.1 - 1.2e-10 40.9 0.0 7e-10 38.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 CDO70926.1 - 5.7e-10 39.3 0.0 1.8e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 CDO70926.1 - 8.8e-08 31.5 0.0 1.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NACHT PF05729.7 CDO70926.1 - 0.00023 20.8 6.9 0.0013 18.4 4.8 2.2 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 CDO70926.1 - 0.0012 19.0 0.0 0.0081 16.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain HATPase_c_3 PF13589.1 CDO70926.1 - 0.0063 16.1 0.0 0.055 13.1 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_29 PF13555.1 CDO70926.1 - 0.022 14.2 0.0 0.064 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CDO70926.1 - 0.041 13.2 0.2 0.23 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CDO70926.1 - 0.15 11.1 0.0 0.35 9.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MFS_1 PF07690.11 CDO70927.1 - 7.1e-55 186.1 51.8 2.6e-43 148.0 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CDO70927.1 - 0.00065 19.4 13.2 0.001 18.7 0.1 4.4 3 1 1 4 4 4 1 MFS_1 like family Acatn PF13000.2 CDO70928.1 - 5.5e-133 444.3 23.9 2.1e-62 211.3 9.0 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF2165 PF09933.4 CDO70928.1 - 0.096 12.4 3.7 1.1 8.9 0.2 2.6 1 1 1 2 2 2 0 Predicted small integral membrane protein (DUF2165) GYF PF02213.11 CDO70929.1 - 4.9e-16 58.0 0.1 1.1e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 GYF domain DUF4339 PF14237.1 CDO70929.1 - 0.036 13.6 0.2 0.11 12.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Atg14 PF10186.4 CDO70931.1 - 5.1e-18 65.0 0.0 9.1e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 PUF PF00806.14 CDO70932.1 - 5.5e-54 176.7 9.9 9.4e-08 31.1 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat DUF260 PF03195.9 CDO70932.1 - 0.011 15.9 0.1 0.094 13.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF260 SET PF00856.23 CDO70933.1 - 1.5e-20 74.1 0.5 6.9e-20 71.9 0.0 2.3 2 2 0 2 2 2 1 SET domain HMG_box PF00505.14 CDO70934.1 - 1.2e-13 51.1 0.6 1.9e-13 50.4 0.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO70934.1 - 0.00022 21.5 0.1 0.00039 20.7 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 CDO70934.1 - 0.00028 20.3 0.1 0.0005 19.4 0.1 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 DHO_dh PF01180.16 CDO70935.1 - 0.0013 17.7 0.0 1.1 8.1 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase TRAPP PF04051.11 CDO70936.1 - 7.9e-40 135.8 0.0 9.5e-40 135.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component BCNT PF07572.7 CDO70938.1 - 4.6e-15 55.3 0.2 6.9e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUF605 PF04652.11 CDO70938.1 - 2.1 7.6 21.1 2.4 7.4 14.6 1.1 1 0 0 1 1 1 0 Vta1 like Cullin PF00888.17 CDO70939.1 - 1.9e-08 33.3 0.0 1.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Med9 PF07544.8 CDO70940.1 - 1.8e-05 24.3 0.2 2.5e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 3H PF02829.9 CDO70940.1 - 0.13 12.2 0.1 0.2 11.7 0.1 1.4 1 1 0 1 1 1 0 3H domain LUC7 PF03194.10 CDO70940.1 - 0.15 11.5 1.2 0.18 11.2 0.8 1.0 1 0 0 1 1 1 0 LUC7 N_terminus Bacillus_HBL PF05791.6 CDO70940.1 - 0.3 10.4 1.7 0.79 9.0 0.2 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CbiG_C PF01890.11 CDO70942.1 - 0.19 11.9 0.6 0.32 11.2 0.4 1.3 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus PAT1 PF09770.4 CDO70942.1 - 8.6 4.4 13.8 12 3.9 9.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PSP1 PF04468.7 CDO70944.1 - 1e-32 111.9 1.6 1.6e-32 111.3 1.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rgp1 PF08737.5 CDO70945.1 - 2.8e-47 161.7 0.0 4.7e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 CDO70945.1 - 0.017 15.2 0.0 15 5.7 0.0 3.1 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain DUF11 PF01345.13 CDO70945.1 - 0.037 14.0 0.2 0.17 11.9 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function DUF11 TrkH PF02386.11 CDO70946.1 - 1.7e-76 257.0 9.3 1.4e-63 214.6 0.1 2.1 2 0 0 2 2 2 2 Cation transport protein PCI PF01399.22 CDO70947.1 - 9.1e-08 32.3 3.4 1.1e-07 32.1 0.4 2.1 2 0 0 2 2 2 1 PCI domain Taxilin PF09728.4 CDO70947.1 - 0.015 14.3 6.3 0.03 13.4 4.4 1.5 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DSBA PF01323.15 CDO70947.1 - 0.019 14.4 2.4 0.032 13.7 1.6 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain DUF3452 PF11934.3 CDO70947.1 - 0.025 13.9 0.1 0.044 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Peptidase_S10 PF00450.17 CDO70948.1 - 2.7e-55 188.2 0.0 4.5e-55 187.5 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase AAA_17 PF13207.1 CDO70949.1 - 3.1e-05 24.7 0.1 0.00019 22.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDO70949.1 - 0.00032 20.9 0.1 0.0012 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 CDO70949.1 - 0.00045 19.8 0.1 0.0041 16.7 0.0 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 CDO70949.1 - 0.0054 15.5 0.0 0.0082 14.9 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 CDO70949.1 - 0.018 15.0 0.1 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 CDO70949.1 - 0.022 14.6 0.3 0.039 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 CDO70949.1 - 0.023 13.9 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.17 CDO70949.1 - 0.04 12.7 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 CDO70949.1 - 0.05 12.7 0.4 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 CDO70949.1 - 0.064 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-C2H2 PF00096.21 CDO70951.1 - 2.8e-08 33.6 12.0 0.00091 19.4 0.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO70951.1 - 1e-06 28.7 11.5 8.9e-06 25.7 0.2 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CDO70951.1 - 0.0098 16.1 11.5 0.36 11.2 0.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CDO70951.1 - 0.019 14.6 1.7 0.019 14.6 1.1 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-CHY PF05495.7 CDO70951.1 - 0.13 12.4 4.1 0.22 11.6 2.8 1.3 1 0 0 1 1 1 0 CHY zinc finger Bromodomain PF00439.20 CDO70952.1 - 3.7e-10 39.5 0.2 1.9e-05 24.5 0.1 3.4 2 1 0 2 2 2 2 Bromodomain BAH PF01426.13 CDO70952.1 - 1.2e-09 37.9 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 BAH domain A_deaminase PF00962.17 CDO70953.1 - 1.1e-16 60.6 0.0 4.9e-16 58.5 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF3752 PF12572.3 CDO70954.1 - 2.6e-28 99.0 8.4 6.6e-28 97.7 5.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3752) adh_short PF00106.20 CDO70955.1 - 1.5e-30 106.3 0.3 2.2e-30 105.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO70955.1 - 1.5e-21 77.2 0.2 2.2e-20 73.4 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO70955.1 - 8.2e-16 58.1 0.2 1.2e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 CDO70955.1 - 0.0089 15.8 0.4 0.017 14.9 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 CDO70955.1 - 0.018 14.6 0.2 0.032 13.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain G-alpha PF00503.15 CDO70956.1 - 2e-93 313.2 1.6 1.2e-73 248.0 0.1 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.16 CDO70956.1 - 6.1e-11 41.8 0.7 1.2e-05 24.6 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 CDO70956.1 - 0.00054 20.4 0.0 0.34 11.4 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 CDO70956.1 - 0.013 15.4 0.0 5 7.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 CDO70956.1 - 0.033 14.4 0.5 0.098 12.9 0.2 1.8 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CDO70956.1 - 0.041 13.4 0.1 0.077 12.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CDO70956.1 - 0.063 12.7 0.6 4.2 6.7 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 CDO70956.1 - 0.072 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 CDO70956.1 - 0.088 11.9 0.4 4 6.4 0.0 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region PORR PF11955.3 CDO70958.1 - 0.094 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Plant organelle RNA recognition domain Cullin PF00888.17 CDO70959.1 - 2e-71 241.3 0.0 1.3e-36 126.3 0.0 2.8 2 1 1 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.4 CDO70959.1 - 1.4e-24 85.7 1.6 3.8e-24 84.2 1.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain SPO22 PF08631.5 CDO70960.1 - 9.6e-18 64.2 4.6 1.3e-14 53.9 0.0 4.1 3 2 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 CDO70960.1 - 0.0015 18.3 7.7 0.37 10.7 0.0 5.1 4 2 1 5 5 5 2 Tetratricopeptide repeat Cyclin PF08613.6 CDO70961.1 - 4.4e-17 62.8 0.7 8.7e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CDO70961.1 - 5.1e-10 39.0 0.0 1.8e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Chs3p PF12271.3 CDO70962.1 - 1.7e-114 381.7 20.5 2e-114 381.5 14.2 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit His_Phos_2 PF00328.17 CDO70963.1 - 6.2e-42 144.1 0.0 7.9e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) tRNA-synt_1c PF00749.16 CDO70964.1 - 6e-87 291.2 0.0 9.4e-87 290.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain HTH_31 PF13560.1 CDO70964.1 - 0.047 13.8 0.2 5.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain zf-UBR PF02207.15 CDO70965.1 - 4.9e-16 58.2 15.4 4.9e-16 58.2 10.6 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CDO70965.1 - 1e-09 37.9 0.0 2.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.4 CDO70965.1 - 0.0081 15.4 0.9 0.13 11.4 0.0 3.0 3 1 0 3 3 3 1 RNA polymerase II elongation factor ELL TRAPP PF04051.11 CDO70966.1 - 8.8e-22 77.2 0.0 1.7e-21 76.3 0.0 1.5 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 CDO70967.1 - 4.3e-09 35.9 0.9 0.21 11.5 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat PGA2 PF07543.7 CDO70967.1 - 0.92 9.2 5.2 1.7 8.4 2.4 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Glyco_transf_25 PF01755.12 CDO70968.1 - 2.4e-05 24.0 0.0 0.00034 20.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) zf-CCHC PF00098.18 CDO70969.1 - 2.6e-05 23.8 2.6 7e-05 22.5 1.8 1.8 1 0 0 1 1 1 1 Zinc knuckle Zn_Tnp_IS91 PF14319.1 CDO70969.1 - 0.016 14.6 2.9 0.025 14.0 2.0 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-CCHC_4 PF14392.1 CDO70969.1 - 0.095 12.3 2.8 0.19 11.4 1.9 1.5 1 0 0 1 1 1 0 Zinc knuckle C_GCAxxG_C_C PF09719.5 CDO70969.1 - 3.2 7.5 6.7 1.1 9.0 2.8 1.6 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Gly_transf_sug PF04488.10 CDO70970.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 CDO70970.1 - 0.0091 15.1 0.2 0.012 14.8 0.1 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DFP PF04127.10 CDO70972.1 - 7.3e-16 58.3 0.0 2.2e-13 50.2 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein DUF1538 PF07556.6 CDO70972.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1538) NST1 PF13945.1 CDO70973.1 - 0.91 9.5 4.5 1.4 8.9 3.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Abhydrolase_6 PF12697.2 CDO70974.1 - 2.2e-31 109.5 2.3 1.2e-30 107.1 1.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO70974.1 - 3.9e-13 49.5 0.0 1.1e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO70974.1 - 2.2e-10 40.4 0.0 3.2e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO70974.1 - 8.8e-07 28.6 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 CDO70974.1 - 0.021 13.6 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase XPG_I PF00867.13 CDO70975.1 - 7.2e-27 93.2 0.0 1.4e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CDO70975.1 - 4.3e-07 30.1 0.0 7.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 CDO70975.1 - 9.2e-05 22.6 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 CDO70975.1 - 0.0017 17.8 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_1 PF00515.23 CDO70975.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 CDO70975.1 - 0.016 15.0 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 CDO70976.1 - 0.00027 21.1 0.7 0.00071 19.7 0.5 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO70976.1 - 0.016 15.4 0.4 0.056 13.8 0.3 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger PIG-P PF08510.7 CDO70977.1 - 2e-22 79.1 3.9 2.5e-22 78.8 2.7 1.1 1 0 0 1 1 1 1 PIG-P 5-FTHF_cyc-lig PF01812.15 CDO70978.1 - 0.16 11.6 0.0 4.1 7.1 0.0 2.1 2 0 0 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family RecA PF00154.16 CDO70979.1 - 1.4e-06 27.6 0.0 2.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.6 CDO70979.1 - 1.3e-05 24.2 0.0 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 CDO70979.1 - 1.5e-05 24.2 0.1 0.00015 20.9 0.1 2.4 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 CDO70979.1 - 0.00022 20.6 0.0 0.00054 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO70979.1 - 0.001 18.7 0.0 0.0033 17.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CDO70979.1 - 0.0096 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RRM_1 PF00076.17 CDO70980.1 - 6e-28 96.2 0.0 1.6e-11 43.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO70980.1 - 4.3e-19 68.2 0.0 9.9e-08 31.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO70980.1 - 7.7e-16 57.6 0.0 2.5e-05 24.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO70980.1 - 0.077 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ABC_tran PF00005.22 CDO70981.1 - 3.8e-31 108.2 0.1 1.3e-16 61.1 0.0 3.2 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 CDO70981.1 - 1.4e-14 53.3 5.5 3.5e-14 52.0 3.8 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CDO70981.1 - 7.2e-13 49.1 6.1 0.044 13.7 0.0 4.8 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 CDO70981.1 - 1.1e-10 41.1 2.8 0.0045 16.2 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 CDO70981.1 - 5.9e-07 28.8 3.2 5.9e-07 28.8 2.2 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.1 CDO70981.1 - 1.2e-06 27.8 0.4 2.8 6.9 0.0 4.3 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 CDO70981.1 - 7.7e-06 26.0 0.0 0.0077 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CDO70981.1 - 1.1e-05 25.5 0.1 0.092 12.9 0.1 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CDO70981.1 - 3.8e-05 23.3 0.9 0.016 14.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 CDO70981.1 - 6.6e-05 22.1 1.6 0.22 10.7 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CDO70981.1 - 8.4e-05 23.3 1.4 0.1 13.3 0.1 3.0 2 2 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CDO70981.1 - 0.00016 21.7 0.1 0.18 11.9 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_29 PF13555.1 CDO70981.1 - 0.00024 20.5 0.9 0.21 11.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 CDO70981.1 - 0.00049 20.5 0.1 0.14 12.6 0.0 3.0 4 0 0 4 4 2 1 Miro-like protein Fer4_6 PF12837.2 CDO70981.1 - 0.0007 19.3 2.3 0.0007 19.3 1.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain VirE PF05272.6 CDO70981.1 - 0.00084 18.8 0.0 0.9 8.9 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E SRP54 PF00448.17 CDO70981.1 - 0.00099 18.6 1.8 0.18 11.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 CDO70981.1 - 0.0011 18.5 0.6 0.024 14.2 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 CDO70981.1 - 0.0011 18.4 0.4 1.3 8.4 0.0 2.7 4 0 0 4 4 2 2 AAA domain AAA_33 PF13671.1 CDO70981.1 - 0.0012 18.7 0.0 0.31 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CDO70981.1 - 0.0012 19.0 0.4 0.25 11.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CDO70981.1 - 0.0014 18.6 0.0 0.61 10.0 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Fer4_2 PF12797.2 CDO70981.1 - 0.0017 18.1 1.8 0.0017 18.1 1.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.1 CDO70981.1 - 0.0022 17.7 0.8 0.0022 17.7 0.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 CDO70981.1 - 0.0027 17.5 11.5 0.0053 16.5 8.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CDO70981.1 - 0.0028 18.0 2.0 0.0028 18.0 1.4 2.3 1 1 2 3 3 3 1 4Fe-4S dicluster domain SbcCD_C PF13558.1 CDO70981.1 - 0.0037 17.1 0.1 1.1 9.2 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 CDO70981.1 - 0.0062 16.2 0.7 3.1 7.5 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.12 CDO70981.1 - 0.0079 15.5 0.1 3.6 6.9 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase Fer4_16 PF13484.1 CDO70981.1 - 0.012 16.3 0.1 0.012 16.3 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 CDO70981.1 - 0.016 15.7 4.3 0.016 15.7 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Rad17 PF03215.10 CDO70981.1 - 0.016 13.8 0.1 0.36 9.4 0.0 2.5 3 0 0 3 3 2 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 CDO70981.1 - 0.016 14.9 1.8 0.56 9.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CDO70981.1 - 0.018 14.9 0.1 10 6.0 0.0 3.2 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.1 CDO70981.1 - 0.022 14.6 0.1 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 CDO70981.1 - 0.025 13.5 0.0 4.1 6.3 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_23 PF13476.1 CDO70981.1 - 0.035 14.4 4.3 0.27 11.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 CDO70981.1 - 0.035 14.3 12.6 0.13 12.5 8.8 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_10 PF12846.2 CDO70981.1 - 0.091 12.1 0.6 6.9 6.0 0.0 2.5 3 0 0 3 3 2 0 AAA-like domain NB-ARC PF00931.17 CDO70981.1 - 0.099 11.4 0.2 3.2 6.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Fer4_8 PF13183.1 CDO70981.1 - 0.12 12.3 9.0 0.11 12.6 0.8 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain DUF815 PF05673.8 CDO70981.1 - 0.15 10.9 0.1 9.6 5.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 CDO70981.1 - 0.16 11.5 0.1 5.5 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CDO70981.1 - 0.22 11.0 1.1 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CDO70981.1 - 0.24 11.0 2.5 23 4.6 0.0 3.4 4 0 0 4 4 3 0 NTPase Fer4_4 PF12800.2 CDO70981.1 - 0.66 10.4 13.1 0.086 13.2 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_13 PF13166.1 CDO70981.1 - 1.3 7.3 4.3 2.1 6.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain Fer4_15 PF13459.1 CDO70981.1 - 4 8.0 9.1 0.23 12.0 0.9 2.7 3 0 0 3 3 2 0 4Fe-4S single cluster domain UQ_con PF00179.21 CDO70982.1 - 3.8e-52 175.4 0.0 4.2e-52 175.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDO70982.1 - 4.5e-05 23.2 0.0 5.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CDO70982.1 - 0.0012 18.7 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CDO70982.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain PIG-S PF10510.4 CDO70983.1 - 8.6e-112 374.4 0.1 1e-111 374.1 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Myb_DNA-binding PF00249.26 CDO70984.1 - 1.6e-16 60.0 0.0 7.9e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO70984.1 - 1.7e-09 37.6 0.1 0.0019 18.2 0.0 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Rotamase_3 PF13616.1 CDO70985.1 - 2.5e-06 27.7 3.6 4.3e-06 26.9 2.4 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 CDO70985.1 - 0.00053 20.6 0.3 0.00053 20.6 0.2 1.9 2 0 0 2 2 2 1 PPIC-type PPIASE domain DUF4638 PF15472.1 CDO70985.1 - 5 6.6 7.2 5.1 6.5 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) AMP-binding PF00501.23 CDO70986.1 - 1.2e-25 89.7 0.0 3.7e-25 88.1 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 CDO70986.1 - 0.069 11.6 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter PCMT PF01135.14 CDO70988.1 - 1e-70 237.5 0.0 1.2e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 CDO70988.1 - 1.5e-07 31.9 0.0 2.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO70988.1 - 6.6e-06 26.1 0.0 2.1e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO70988.1 - 1.2e-05 24.9 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO70988.1 - 3.3e-05 23.6 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CDO70988.1 - 7.4e-05 22.4 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CDO70988.1 - 0.016 16.0 0.0 0.16 12.8 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain MetW PF07021.7 CDO70988.1 - 0.021 14.1 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.1 CDO70988.1 - 0.022 15.1 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CDO70988.1 - 0.043 14.3 0.0 0.081 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CDO70988.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PPTA PF01239.17 CDO70989.1 - 1.7e-44 147.3 10.8 1.1e-08 34.0 0.9 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat SnAPC_2_like PF11035.3 CDO70989.1 - 0.029 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2-like TPR_14 PF13428.1 CDO70989.1 - 0.13 12.9 0.2 23 6.0 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4219 PF13961.1 CDO70989.1 - 3.4 7.2 6.6 13 5.3 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) RRM_1 PF00076.17 CDO70990.1 - 5.7e-14 51.4 0.0 8.6e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO70990.1 - 7.8e-10 38.5 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CDO70990.1 - 7.9e-08 32.6 0.4 7.9e-08 32.6 0.3 2.7 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 CDO70990.1 - 0.00095 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARS2 PF04959.8 CDO70990.1 - 0.15 12.2 0.2 0.15 12.2 0.1 1.5 2 0 0 2 2 2 0 Arsenite-resistance protein 2 RNA_pol_3_Rpc31 PF11705.3 CDO70991.1 - 2.8e-33 115.8 25.2 7.8e-33 114.3 17.4 1.7 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.9 CDO70991.1 - 0.54 9.7 2.8 0.75 9.2 1.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Serglycin PF04360.7 CDO70992.1 - 0.011 15.4 3.6 0.023 14.3 2.5 1.6 1 0 0 1 1 1 0 Serglycin p450 PF00067.17 CDO70993.1 - 1.3e-65 221.7 0.0 2.8e-65 220.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 CDO70994.1 - 5.6e-09 36.1 0.7 2.5e-07 30.7 0.0 2.4 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 CDO70994.1 - 0.00012 21.9 0.0 0.00096 18.9 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO70994.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 CDO70995.1 - 8.3e-16 58.3 0.2 1.6e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO70995.1 - 7.3e-07 29.2 0.0 9.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CDO70995.1 - 0.00011 22.2 0.2 0.0003 20.8 0.1 1.8 1 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 CDO70995.1 - 0.0052 16.4 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO70995.1 - 0.0061 16.0 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GMC_oxred_C PF05199.8 CDO70997.1 - 4.1e-39 134.1 0.0 5.9e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CDO70997.1 - 6.5e-09 35.3 0.0 0.0014 17.8 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase TFIIB PF00382.14 CDO70998.1 - 1.1e-37 127.6 1.3 1.1e-18 66.7 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CDO70998.1 - 1.9e-24 85.7 14.8 9.8e-24 83.4 4.3 2.6 2 0 0 2 2 2 2 Brf1-like TBP-binding domain Cyclin_N PF00134.18 CDO70998.1 - 6.8e-09 35.3 0.6 0.0015 18.0 0.2 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 CDO70998.1 - 1.8e-07 30.3 5.3 3.9e-07 29.2 3.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 CDO70998.1 - 0.015 14.7 2.8 0.029 13.8 1.9 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain RRN7 PF11781.3 CDO70998.1 - 2 7.9 8.7 0.21 11.0 2.7 1.9 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 RVT_1 PF00078.22 CDO70999.1 - 2e-21 76.3 0.0 3.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CDO70999.1 - 1.9e-13 50.0 0.0 5.3e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CDO70999.1 - 2.1e-07 31.1 0.2 7.3e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RVT_2 PF07727.9 CDO71000.1 - 3.8e-72 242.2 0.0 6.5e-72 241.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO71000.1 - 8.2e-22 77.5 0.5 1.8e-21 76.4 0.4 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CDO71000.1 - 4.2e-06 26.2 0.0 8.8e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 CDO71000.1 - 3.1e-05 23.6 3.0 5.8e-05 22.8 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 CDO71000.1 - 0.00027 20.6 0.0 0.00056 19.6 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO71000.1 - 0.00041 19.9 0.0 0.0011 18.4 0.0 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CDO71000.1 - 0.0091 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 CDO71000.1 - 0.065 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain IncA PF04156.9 CDO71001.1 - 0.2 11.2 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 IncA protein NOA36 PF06524.7 CDO71001.1 - 0.27 10.4 7.9 0.46 9.7 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 CDO71001.1 - 4.3 5.6 11.7 7.5 4.8 8.1 1.4 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 CDO71001.1 - 4.9 6.6 13.7 8.1 5.9 9.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 CDO71001.1 - 5.9 6.6 9.2 12 5.7 6.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal E1-E2_ATPase PF00122.15 CDO71002.1 - 2.8e-58 196.6 0.2 2.8e-58 196.6 0.1 2.6 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CDO71002.1 - 7.1e-24 85.4 0.2 1.8e-23 84.1 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDO71002.1 - 7.5e-15 55.6 0.1 1.6e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CDO71002.1 - 5.1e-14 51.4 0.0 1.4e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CDO71002.1 - 2e-05 24.2 0.0 9.3e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3650 PF12368.3 CDO71002.1 - 0.12 11.9 1.2 0.19 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) PGA2 PF07543.7 CDO71003.1 - 0.84 9.4 6.9 0.45 10.2 3.3 1.6 1 1 1 2 2 2 0 Protein trafficking PGA2 DUF1996 PF09362.5 CDO71004.1 - 3.2e-61 206.9 0.6 7.7e-60 202.4 0.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 CDO71004.1 - 0.0004 20.2 3.5 0.00091 19.1 2.5 1.6 1 0 0 1 1 1 1 WSC domain Transket_pyr PF02779.19 CDO71005.1 - 2.1e-45 154.4 0.0 5.4e-45 153.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CDO71005.1 - 1.5e-22 79.6 0.0 2.3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Aldo_ket_red PF00248.16 CDO71006.1 - 2e-50 171.2 0.0 2.3e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD PF12710.2 CDO71007.1 - 2.3e-10 40.9 0.0 3.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CDO71007.1 - 8.7e-06 26.0 0.0 0.00016 21.9 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 CDO71007.1 - 1.3e-05 24.6 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 CDO71007.1 - 0.0006 20.2 0.0 0.0008 19.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.7 CDO71007.1 - 0.022 14.8 0.0 5.9 7.1 0.0 2.7 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Put_Phosphatase PF06888.7 CDO71007.1 - 0.059 12.5 0.0 0.32 10.1 0.0 2.1 3 0 0 3 3 3 0 Putative Phosphatase DUF3148 PF11347.3 CDO71007.1 - 0.13 11.9 0.0 7.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) DUF1996 PF09362.5 CDO71008.1 - 1.3e-69 234.4 0.5 3.3e-69 233.1 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 CDO71008.1 - 1.5e-12 47.2 7.4 3.5e-12 46.0 5.1 1.6 1 0 0 1 1 1 1 WSC domain Ribosomal_S6e PF01092.14 CDO71009.1 - 2.5e-61 204.9 0.1 4.9e-61 203.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.7 CDO71010.1 - 8.5e-31 105.5 0.1 1.5e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CDO71010.1 - 1.3e-22 79.2 0.1 1.7e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 CDO71010.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 'Paired box' domain UPF0220 PF05255.6 CDO71011.1 - 3.2e-49 166.3 0.0 4.1e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) GPI-anchored PF10342.4 CDO71012.1 - 0.00039 20.8 0.2 0.0006 20.2 0.1 1.3 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CDO71012.1 - 0.0009 18.7 0.0 0.00097 18.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Kelch_6 PF13964.1 CDO71013.1 - 6.3e-21 73.6 6.5 1.4e-05 25.0 0.0 6.8 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.1 CDO71013.1 - 1.6e-20 72.6 5.1 0.0021 17.7 0.0 6.9 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 CDO71013.1 - 6.7e-18 64.3 9.5 0.0088 16.1 0.0 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.20 CDO71013.1 - 8.9e-15 53.9 5.0 0.00011 21.6 0.0 6.4 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.1 CDO71013.1 - 4.6e-13 48.8 9.4 0.0095 15.8 0.1 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CDO71013.1 - 1.1e-06 28.2 3.9 0.95 9.3 0.1 6.1 5 1 0 5 5 5 1 Kelch motif zf-MYND PF01753.13 CDO71013.1 - 0.00058 19.6 13.8 0.0025 17.6 9.6 2.1 1 0 0 1 1 1 1 MYND finger DUF3328 PF11807.3 CDO71013.1 - 0.026 14.2 0.0 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) TPR_10 PF13374.1 CDO71013.1 - 0.12 12.3 0.0 0.55 10.2 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1572 PF07609.6 CDO71013.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) HMG_box PF00505.14 CDO71015.1 - 1.9e-08 34.4 10.4 7.7e-08 32.4 7.2 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO71015.1 - 6.3e-08 32.8 6.2 1.5e-07 31.6 4.3 1.6 1 0 0 1 1 1 1 HMG-box domain HhH-GPD PF00730.20 CDO71016.1 - 2.8e-11 43.6 0.0 5.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF937 PF06078.6 CDO71016.1 - 0.015 15.4 0.2 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) HHH PF00633.18 CDO71016.1 - 0.079 12.6 0.0 0.29 10.9 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif DHOase PF12890.2 CDO71016.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Dihydro-orotase-like HMG_box PF00505.14 CDO71018.1 - 7.5e-12 45.3 0.1 1.6e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO71018.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain Thioredoxin PF00085.15 CDO71019.1 - 2e-60 200.9 0.1 1.9e-29 101.3 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CDO71019.1 - 6.6e-22 77.8 0.2 5.7e-10 39.3 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain ERp29 PF07749.7 CDO71019.1 - 2.5e-21 76.1 2.1 4.6e-21 75.2 0.8 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_8 PF13905.1 CDO71019.1 - 9.7e-14 51.2 0.1 6.8e-05 22.9 0.0 3.9 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CDO71019.1 - 5.3e-13 48.8 0.0 1.8e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.1 CDO71019.1 - 4.4e-12 46.1 0.0 3.2e-05 23.8 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain AhpC-TSA PF00578.16 CDO71019.1 - 2.9e-08 33.4 0.1 0.0022 17.6 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 CDO71019.1 - 7.8e-08 31.9 0.2 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 CDO71019.1 - 0.00018 21.0 0.5 0.22 11.0 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 CDO71019.1 - 0.00039 20.1 0.0 0.085 12.6 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.1 CDO71019.1 - 0.00059 19.8 1.4 1.7 8.6 0.0 3.3 3 1 1 4 4 4 2 Thioredoxin Glutaredoxin PF00462.19 CDO71019.1 - 0.0018 18.2 0.1 0.12 12.4 0.0 2.8 2 0 0 2 2 2 1 Glutaredoxin DDE_Tnp_1_2 PF13586.1 CDO71019.1 - 0.032 14.4 0.0 3.8 7.7 0.0 3.1 2 1 0 2 2 2 0 Transposase DDE domain GTSE1_N PF15259.1 CDO71019.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 DUF953 PF06110.6 CDO71019.1 - 0.066 12.6 0.2 1 8.8 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) TraF PF13728.1 CDO71019.1 - 0.075 12.5 0.0 6.7 6.1 0.0 2.4 2 0 0 2 2 2 0 F plasmid transfer operon protein adh_short_C2 PF13561.1 CDO71020.1 - 6.5e-27 94.8 0.0 7.9e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO71020.1 - 6.5e-26 91.2 0.0 8.4e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO71020.1 - 2.1e-06 27.4 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 CDO71020.1 - 0.0012 17.9 0.0 0.0026 16.8 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MM_CoA_mutase PF01642.17 CDO71020.1 - 0.0031 15.7 0.0 0.0046 15.1 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase Eno-Rase_NADH_b PF12242.3 CDO71020.1 - 0.005 16.5 0.1 0.014 15.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 CDO71020.1 - 0.017 14.7 0.5 1.3 8.5 0.1 2.9 2 1 1 3 3 3 0 DNA / pantothenate metabolism flavoprotein OTCace PF00185.19 CDO71020.1 - 0.034 14.0 0.0 0.082 12.7 0.0 1.6 1 1 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF1776 PF08643.5 CDO71020.1 - 0.035 13.2 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pyr_redox PF00070.22 CDO71020.1 - 0.1 13.0 0.1 0.57 10.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 CDO71020.1 - 0.11 12.4 0.1 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding tRNA-synt_1d PF00750.14 CDO71021.1 - 7.6e-85 284.8 4.4 1e-84 284.4 3.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CDO71021.1 - 3.5e-22 78.5 0.0 8e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain HemN_C PF06969.11 CDO71021.1 - 0.0055 16.7 0.1 0.09 12.8 0.0 2.5 2 0 0 2 2 2 1 HemN C-terminal domain DUF706 PF05153.10 CDO71022.1 - 5e-131 435.5 2.6 6.9e-131 435.1 1.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 CDO71022.1 - 0.00044 20.2 0.0 0.012 15.5 0.0 2.5 2 0 0 2 2 2 1 HD domain HD_4 PF13328.1 CDO71022.1 - 0.065 12.9 0.2 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 HD domain DUF3864 PF12980.2 CDO71022.1 - 0.078 13.1 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) Metallophos PF00149.23 CDO71023.1 - 3.6e-10 39.5 3.7 1.4e-06 27.8 0.1 2.3 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDO71023.1 - 1.4e-08 34.7 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HMG_box PF00505.14 CDO71024.1 - 7.4e-13 48.5 0.3 1.5e-12 47.5 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO71024.1 - 0.0013 19.0 0.0 0.003 17.9 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain AA_permease_2 PF13520.1 CDO71025.1 - 5.4e-78 262.4 38.0 6.8e-78 262.0 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CDO71026.1 - 4.8e-75 252.6 38.9 6.1e-75 252.3 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.27 CDO71027.1 - 6.8e-25 85.9 12.7 1.3e-08 34.4 0.1 5.7 6 1 1 7 7 7 4 WD domain, G-beta repeat BBS2_N PF14781.1 CDO71027.1 - 0.069 12.7 0.0 1.2 8.7 0.0 2.8 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal Peptidase_C14 PF00656.17 CDO71029.1 - 8.3e-22 78.0 0.0 3.7e-20 72.6 0.0 2.7 1 1 0 1 1 1 1 Caspase domain DUF2993 PF11209.3 CDO71032.1 - 0.0037 17.2 0.1 0.0049 16.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) Cellulase PF00150.13 CDO71033.1 - 2e-15 56.7 0.0 1.6e-13 50.4 0.0 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 CDO71033.1 - 0.0006 20.2 0.0 0.0021 18.4 0.0 1.9 1 1 0 1 1 1 1 Sugar-binding cellulase-like F-box-like PF12937.2 CDO71034.1 - 2.2e-08 33.6 0.5 6.4e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like DNA_pol_A PF00476.15 CDO71037.1 - 1.6e-93 313.3 0.0 3.7e-93 312.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family A Vpu PF00558.14 CDO71037.1 - 0.022 14.3 2.0 0.053 13.0 1.4 1.6 1 0 0 1 1 1 0 Vpu protein Mt_ATP-synt_B PF05405.9 CDO71037.1 - 0.78 9.1 4.8 1.4 8.3 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) COesterase PF00135.23 CDO71038.1 - 3.3e-49 168.0 0.0 4.7e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CDO71038.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Perilipin PF03036.11 CDO71039.1 - 1.5e-16 60.2 11.4 2.5e-13 49.6 0.0 2.0 1 1 1 2 2 2 2 Perilipin family Apolipoprotein PF01442.13 CDO71039.1 - 5.4e-05 22.7 10.4 0.071 12.6 5.9 3.3 2 2 0 2 2 2 1 Apolipoprotein A1/A4/E domain Gp-FAR-1 PF05823.7 CDO71039.1 - 0.012 15.5 0.4 0.26 11.2 0.0 2.6 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoO PF09769.4 CDO71039.1 - 0.038 13.6 1.7 0.072 12.8 0.6 1.8 1 1 0 1 1 1 0 Apolipoprotein O ArsR PF09824.4 CDO71039.1 - 0.046 13.0 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 ArsR transcriptional regulator Phasin PF05597.6 CDO71039.1 - 0.18 11.5 2.4 2.9 7.6 0.1 3.0 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Prominin PF05478.6 CDO71039.1 - 0.22 8.9 5.8 0.4 8.1 4.0 1.4 1 0 0 1 1 1 0 Prominin SF-assemblin PF06705.6 CDO71039.1 - 0.32 10.1 3.0 0.53 9.3 0.4 2.4 2 2 0 2 2 2 0 SF-assemblin/beta giardin DUF883 PF05957.8 CDO71039.1 - 1.6 9.1 8.5 8.5 6.8 0.9 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 CDO71039.1 - 3.8 7.3 11.8 3 7.6 3.3 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 CDO71039.1 - 5.4 6.7 7.5 13 5.5 5.0 1.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CBS PF00571.23 CDO71040.1 - 2.5e-20 72.0 1.6 1.3e-06 28.1 0.1 4.5 4 0 0 4 4 4 4 CBS domain CNH PF00780.17 CDO71042.1 - 2e-12 47.1 0.0 4.7e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 CDO71043.1 - 1.7e-11 44.2 0.4 6.5e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 CDO71043.1 - 4.1e-07 29.9 2.6 1.9e-06 27.8 0.1 3.0 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 Cys_Met_Meta_PP PF01053.15 CDO71044.1 - 1.1e-21 76.6 0.0 1.5e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CDO71044.1 - 1.4e-05 24.2 0.0 2.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II PDE6_gamma PF04868.7 CDO71044.1 - 0.058 13.2 0.0 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit RabGAP-TBC PF00566.13 CDO71045.1 - 6.2e-23 81.3 0.0 8.4e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribonuc_L-PSP PF01042.16 CDO71047.1 - 6.9e-18 64.5 0.0 8.1e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribonuc_L-PSP PF01042.16 CDO71048.1 - 7e-12 45.1 0.1 7.8e-12 45.0 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PLDc_3 PF13918.1 CDO71048.1 - 0.022 14.2 0.1 0.034 13.5 0.0 1.5 1 1 1 2 2 2 0 PLD-like domain HMG_box PF00505.14 CDO71049.1 - 2.5e-10 40.4 0.2 4.3e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO71049.1 - 0.0017 18.6 0.1 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain AMP-binding PF00501.23 CDO71051.1 - 5.7e-24 84.2 0.0 8.1e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 CDO71051.1 - 0.023 13.2 0.0 0.036 12.5 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter EAP30 PF04157.11 CDO71052.1 - 1.2e-55 188.0 0.0 1.8e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family AP_endonuc_2 PF01261.19 CDO71054.1 - 2.7e-29 102.0 0.0 3.8e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PaREP1 PF05942.6 CDO71054.1 - 0.039 13.8 0.1 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family Meth_synt_2 PF01717.13 CDO71055.1 - 3.7e-12 45.8 0.0 5.3e-11 42.0 0.0 2.2 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CDO71055.1 - 2.3e-07 30.3 0.0 0.0008 18.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Kelch_4 PF13418.1 CDO71059.1 - 1.5e-32 111.0 9.4 3.4e-07 29.9 0.1 6.6 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CDO71059.1 - 7.6e-31 105.5 7.0 1.9e-08 34.1 0.1 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.20 CDO71059.1 - 5.7e-22 76.9 9.8 3.6e-06 26.4 0.0 5.2 5 1 0 5 5 5 4 Kelch motif DUF4110 PF13422.1 CDO71059.1 - 9.4e-22 76.6 0.1 9.4e-22 76.6 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 CDO71059.1 - 1.6e-21 75.4 11.0 7.6e-06 25.8 0.1 6.1 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.1 CDO71059.1 - 1.7e-18 66.1 12.8 7.1e-05 22.6 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CDO71059.1 - 7.2e-16 57.2 10.8 3e-05 23.6 0.1 5.6 4 1 0 4 4 4 4 Kelch motif Lipase_3 PF01764.20 CDO71060.1 - 6.7e-23 80.8 0.0 9.4e-23 80.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 CDO71060.1 - 0.11 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrophobin PF01185.13 CDO71061.1 - 8.4e-23 80.6 7.9 1e-22 80.3 5.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.7 CDO71061.1 - 5.3 7.6 8.1 2.4 8.7 0.7 2.4 2 0 0 2 2 2 0 Ion channel inhibitory toxin Abi PF02517.11 CDO71063.1 - 0.00011 22.2 1.0 0.00036 20.6 0.3 2.0 2 0 0 2 2 2 1 CAAX protease self-immunity FUSC-like PF12805.2 CDO71063.1 - 0.027 13.3 0.3 0.043 12.7 0.2 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS zf-MYND PF01753.13 CDO71065.1 - 2e-10 40.3 20.7 2.1e-10 40.2 12.1 2.3 2 1 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 CDO71065.1 - 0.51 10.2 9.5 9.2 6.2 5.7 2.5 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3844 PF12955.2 CDO71065.1 - 1.4 9.0 7.7 0.31 11.1 2.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) Sugar_tr PF00083.19 CDO71066.1 - 6.4e-84 282.1 21.1 6.5e-75 252.4 8.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CDO71066.1 - 5.3e-15 54.9 40.5 7.8e-07 28.1 18.0 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF3040 PF11239.3 CDO71066.1 - 0.47 10.5 3.4 11 6.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF2296 PF10058.4 CDO71067.1 - 5.1e-20 70.9 0.3 8.1e-20 70.3 0.2 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Zn_Tnp_IS1595 PF12760.2 CDO71067.1 - 0.21 11.4 1.4 0.3 10.9 0.4 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CDO71067.1 - 0.3 10.6 4.8 1.3 8.5 3.3 1.9 1 1 1 2 2 2 0 A2L zinc ribbon domain zf-RanBP PF00641.13 CDO71067.1 - 0.34 10.0 1.8 0.39 9.8 0.1 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Band_7 PF01145.20 CDO71068.1 - 0.00077 19.4 13.1 0.0028 17.5 7.0 3.0 2 1 0 2 2 2 1 SPFH domain / Band 7 family Glyco_transf_20 PF00982.16 CDO71069.1 - 3.9e-154 513.6 0.0 7.5e-154 512.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CDO71069.1 - 3.7e-73 245.3 0.0 8.7e-73 244.0 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase RRM_1 PF00076.17 CDO71070.1 - 8.6e-50 166.2 0.0 3.4e-15 55.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO71070.1 - 2.9e-35 120.0 0.0 1.3e-11 44.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO71070.1 - 6.6e-20 70.7 0.0 4.9e-05 23.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CDO71070.1 - 3.7e-05 23.3 0.0 0.05 13.3 0.0 3.6 4 1 0 4 4 4 1 Limkain b1 DUF1777 PF08648.7 CDO71070.1 - 7.2e-05 22.5 28.0 0.00013 21.7 19.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) DUF3343 PF11823.3 CDO71070.1 - 0.049 12.8 0.0 0.24 10.6 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) MIP-T3 PF10243.4 CDO71070.1 - 0.28 9.5 10.8 0.4 9.0 7.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PRP38_assoc PF12871.2 CDO71070.1 - 1.2 9.7 48.0 0.81 10.2 28.9 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Rax2 PF12768.2 CDO71071.1 - 0.0039 16.4 0.2 0.0076 15.4 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity SKG6 PF08693.5 CDO71071.1 - 0.007 15.6 5.0 0.007 15.6 3.5 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain VSP PF03302.8 CDO71071.1 - 0.0079 14.8 3.1 0.012 14.2 2.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Herpes_gE PF02480.11 CDO71071.1 - 0.015 13.5 0.0 0.024 12.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1180 PF06679.7 CDO71071.1 - 0.017 15.0 1.9 0.02 14.7 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.1 CDO71071.1 - 0.11 12.9 0.9 0.2 12.0 0.7 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CBM_6 PF03422.10 CDO71071.1 - 0.21 11.7 3.0 16 5.6 2.1 2.6 1 1 0 1 1 1 0 Carbohydrate binding module (family 6) DUF1517 PF07466.6 CDO71071.1 - 0.88 8.4 6.3 0.082 11.8 1.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) DUF791 PF05631.9 CDO71072.1 - 2.6e-55 187.5 6.8 3.9e-55 186.9 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 CDO71072.1 - 6.1e-18 64.6 26.9 6.1e-18 64.6 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF981 PF06168.6 CDO71072.1 - 0.059 13.1 6.8 0.17 11.6 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF981) Sec23_trunk PF04811.10 CDO71073.1 - 5.6e-57 192.8 0.0 8.6e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CDO71073.1 - 1.8e-35 120.4 0.3 3.6e-35 119.5 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CDO71073.1 - 1.5e-26 92.7 0.0 3.1e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CDO71073.1 - 2.2e-15 56.0 0.0 6.1e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat MFS_1 PF07690.11 CDO71074.1 - 4.3e-08 32.2 22.8 3.4e-06 26.0 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 CDO71075.1 - 4.3e-07 28.9 1.6 4.3e-07 28.9 1.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CDO71075.1 - 0.012 14.0 2.6 0.023 13.1 1.8 1.5 1 1 0 1 1 1 0 MFS/sugar transport protein Sugar_tr PF00083.19 CDO71075.1 - 0.17 10.3 4.9 0.02 13.4 0.2 1.8 2 1 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.11 CDO71078.1 - 0.0007 18.4 13.6 0.031 13.0 5.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_A22B PF04258.8 CDO71078.1 - 0.053 12.9 0.0 0.085 12.2 0.0 1.3 1 1 0 1 1 1 0 Signal peptide peptidase ApoO PF09769.4 CDO71079.1 - 9.8e-33 113.0 0.9 8.1e-31 106.8 0.0 2.2 2 0 0 2 2 2 2 Apolipoprotein O LEA_4 PF02987.11 CDO71079.1 - 0.037 13.8 17.0 0.11 12.3 11.1 2.2 1 1 1 2 2 2 0 Late embryogenesis abundant protein DUF883 PF05957.8 CDO71079.1 - 0.04 14.3 7.9 0.58 10.5 2.3 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 CDO71079.1 - 0.15 11.5 9.7 0.81 9.1 5.1 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Phasin PF05597.6 CDO71079.1 - 0.31 10.8 10.9 2.3 7.9 0.0 2.5 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Asr PF06392.6 CDO71079.1 - 3.4 8.0 6.2 15 6.0 2.6 2.6 1 1 1 2 2 2 0 Acid shock protein repeat Mem_trans PF03547.13 CDO71081.1 - 1.2e-42 145.6 0.1 1.9e-40 138.3 0.1 2.5 1 1 0 1 1 1 1 Membrane transport protein ADIP PF11559.3 CDO71082.1 - 0.0051 16.7 2.8 0.011 15.6 1.9 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Myb_DNA-bind_5 PF13873.1 CDO71082.1 - 0.02 14.7 0.5 0.055 13.3 0.4 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Kinesin-relat_1 PF12711.2 CDO71082.1 - 0.036 14.4 6.7 0.22 11.9 3.9 2.5 2 0 0 2 2 2 0 Kinesin motor Spc42p PF11544.3 CDO71082.1 - 0.044 13.7 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p APG6 PF04111.7 CDO71082.1 - 0.054 12.5 4.5 0.097 11.7 3.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.13 CDO71082.1 - 0.3 10.8 3.8 0.44 10.3 1.6 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Macoilin PF09726.4 CDO71082.1 - 4.9 5.2 10.6 11 4.2 7.3 1.6 1 1 0 1 1 1 0 Transmembrane protein DDE_Tnp_4 PF13359.1 CDO71083.1 - 1.8e-11 43.9 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Zn_clus PF00172.13 CDO71084.1 - 0.0035 17.2 12.8 0.0053 16.6 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAM33 PF02330.11 CDO71085.1 - 1.7e-34 119.3 0.0 2.3e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein HTH_Tnp_Tc3_2 PF01498.13 CDO71087.1 - 7.7e-06 25.8 0.1 1.8e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 CDO71087.1 - 9.3e-06 26.3 0.1 1.4e-05 25.7 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CDO71087.1 - 1.1e-05 25.5 0.2 1.3e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 CDO71087.1 - 0.0002 20.8 1.0 0.0011 18.5 0.1 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 CDO71087.1 - 0.12 12.3 0.2 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PRCC PF10253.4 CDO71088.1 - 0.53 10.9 2.6 0.8 10.3 1.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MFS_1 PF07690.11 CDO71091.1 - 4.4e-09 35.5 18.9 5.9e-09 35.0 13.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CDO71091.1 - 7.8e-06 25.5 1.3 0.15 11.9 0.7 2.4 2 0 0 2 2 2 2 MFS_1 like family RNase_PH PF01138.16 CDO71092.1 - 4.1e-15 56.2 0.1 6.3e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 LRR_6 PF13516.1 CDO71093.1 - 3.3e-10 38.9 4.5 0.08 13.0 0.1 6.3 6 0 0 6 6 6 3 Leucine Rich repeat PsbI PF02532.9 CDO71093.1 - 0.011 15.3 0.3 0.028 14.0 0.2 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) LRR_7 PF13504.1 CDO71093.1 - 0.018 15.1 4.4 1.8e+02 3.0 0.1 6.0 5 0 0 5 5 5 0 Leucine rich repeat F-box PF00646.28 CDO71093.1 - 0.033 13.8 0.8 0.078 12.6 0.2 2.0 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 CDO71093.1 - 0.16 11.7 0.9 0.53 10.0 0.6 2.0 1 1 0 1 1 1 0 F-box-like LRR_4 PF12799.2 CDO71093.1 - 0.41 10.3 8.5 14 5.4 0.6 4.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) TFIIE_alpha PF02002.12 CDO71094.1 - 1.3e-17 63.2 0.1 2.2e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C-term PF11521.3 CDO71094.1 - 0.00015 21.5 0.6 0.00045 20.1 0.4 1.7 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha TF_Zn_Ribbon PF08271.7 CDO71094.1 - 0.0023 17.2 0.3 0.0023 17.2 0.2 1.9 2 0 0 2 2 2 1 TFIIB zinc-binding PDZ PF00595.19 CDO71094.1 - 0.0046 17.0 0.0 0.018 15.2 0.0 2.0 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) zf-C2H2_6 PF13912.1 CDO71094.1 - 0.0097 15.7 1.5 0.13 12.1 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 CDO71094.1 - 0.12 12.1 0.1 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-HYPF PF07503.7 CDO71094.1 - 0.13 11.7 0.1 0.24 10.8 0.1 1.5 1 0 0 1 1 1 0 HypF finger DiS_P_DiS PF06750.8 CDO71094.1 - 0.15 11.8 0.1 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain adh_short PF00106.20 CDO71095.1 - 2.5e-09 37.2 0.1 4.5e-08 33.1 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO71095.1 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short_C2 PF13561.1 CDO71096.1 - 1.5e-05 24.8 0.0 1.9e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Aldo_ket_red PF00248.16 CDO71098.1 - 6.8e-51 172.7 0.0 8e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PX PF00787.19 CDO71099.1 - 2.8e-15 56.1 0.0 6.4e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 CDO71099.1 - 1e-12 47.8 0.5 1.2e-11 44.3 0.3 2.0 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein WD40 PF00400.27 CDO71101.1 - 2.5e-92 299.7 61.8 1.3e-10 40.7 1.8 13.2 13 0 0 13 13 13 12 WD domain, G-beta repeat eIF2A PF08662.6 CDO71101.1 - 2.6e-10 40.3 1.1 0.011 15.4 0.1 3.5 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A NACHT PF05729.7 CDO71101.1 - 1.4e-06 28.1 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 CDO71101.1 - 1.1e-05 25.0 0.1 0.00095 18.8 0.0 3.3 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 CDO71101.1 - 1.7e-05 24.8 0.0 6.3e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CDO71101.1 - 0.00021 21.4 0.0 0.00047 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytochrom_D1 PF02239.11 CDO71101.1 - 0.00059 18.2 1.1 0.011 14.0 0.1 3.1 3 0 0 3 3 3 1 Cytochrome D1 heme domain AAA_25 PF13481.1 CDO71101.1 - 0.0044 16.4 0.0 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 CDO71101.1 - 0.0079 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Nup160 PF11715.3 CDO71101.1 - 0.0082 14.3 16.1 0.12 10.4 0.1 4.2 2 2 1 4 4 4 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 CDO71101.1 - 0.01 14.6 0.0 0.24 10.1 0.0 2.3 2 0 0 2 2 2 0 Coatomer WD associated region IncA PF04156.9 CDO71101.1 - 0.021 14.3 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 IncA protein AAA_30 PF13604.1 CDO71101.1 - 0.059 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CDO71101.1 - 0.071 13.9 0.2 1.1 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3312 PF11768.3 CDO71101.1 - 0.075 11.2 0.3 3.3 5.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) AAA_23 PF13476.1 CDO71101.1 - 0.24 11.6 0.0 1.6 9.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Malic_M PF03949.10 CDO71102.1 - 1.8e-82 276.7 0.0 2.4e-82 276.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CDO71102.1 - 6.5e-64 214.8 0.0 1e-63 214.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RRM_5 PF13893.1 CDO71105.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med15 PF09606.5 CDO71105.1 - 0.006 14.8 4.0 0.15 10.2 0.2 2.7 3 0 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal RRM_6 PF14259.1 CDO71105.1 - 0.046 13.6 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Angiomotin_C PF12240.3 CDO71105.1 - 0.81 9.1 6.5 0.16 11.4 0.5 2.2 2 0 0 2 2 2 0 Angiomotin C terminal Peptidase_S41 PF03572.13 CDO71106.1 - 0.00019 20.8 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 DUF508 PF04370.7 CDO71107.1 - 0.063 12.9 0.3 0.095 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) FixP_N PF14715.1 CDO71107.1 - 0.075 12.4 0.5 22 4.5 0.0 3.1 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP 7tm_7 PF08395.7 CDO71107.1 - 0.099 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Amino_oxidase PF01593.19 CDO71108.1 - 7e-14 51.7 0.7 4.4e-07 29.3 0.2 3.0 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CDO71108.1 - 6e-11 42.2 0.0 1.5e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO71108.1 - 2.6e-09 36.4 0.4 3e-08 32.9 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CDO71108.1 - 1.2e-05 25.0 0.4 0.0005 19.8 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CDO71108.1 - 0.00012 22.1 0.0 0.022 14.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO71108.1 - 0.0053 15.2 0.0 0.37 9.2 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 CDO71108.1 - 0.0057 16.5 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO71108.1 - 0.0069 16.7 0.0 0.04 14.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CDO71108.1 - 0.016 13.8 0.0 0.024 13.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Strep_67kDa_ant PF06100.6 CDO71108.1 - 0.025 12.9 0.0 0.035 12.4 0.0 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family GIDA PF01134.17 CDO71108.1 - 0.034 13.0 0.1 2.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 CDO71108.1 - 0.034 13.2 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 CDO71108.1 - 0.065 12.3 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 CDO71108.1 - 0.11 11.2 0.2 0.36 9.6 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain DNA_primase_S PF01896.14 CDO71109.1 - 4e-42 143.4 0.0 9e-42 142.3 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit ABC_tran PF00005.22 CDO71111.1 - 2.5e-41 141.1 0.0 2.6e-27 95.7 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CDO71111.1 - 2.5e-28 99.2 24.2 1.5e-14 54.1 0.4 4.7 4 1 0 4 4 4 2 ABC transporter transmembrane region AAA_25 PF13481.1 CDO71111.1 - 0.00012 21.5 0.1 0.43 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CDO71111.1 - 0.00018 20.9 0.4 0.21 11.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 CDO71111.1 - 0.0012 18.3 0.0 1.9 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain SMC_N PF02463.14 CDO71111.1 - 0.0018 17.5 0.1 0.74 8.9 0.0 3.5 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDO71111.1 - 0.0074 16.2 1.6 25 4.7 0.0 3.8 2 2 1 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 CDO71111.1 - 0.0096 15.4 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 CDO71111.1 - 0.01 15.8 0.1 1 9.3 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CDO71111.1 - 0.024 14.7 0.1 10 6.2 0.0 3.1 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 CDO71111.1 - 0.027 13.3 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.12 CDO71111.1 - 0.066 13.0 1.7 0.13 12.1 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 CDO71111.1 - 0.066 13.5 0.2 8 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SieB PF14163.1 CDO71111.1 - 0.12 11.8 3.1 0.1 12.1 0.9 1.8 2 0 0 2 2 2 0 Superinfection exclusion protein B Miro PF08477.8 CDO71111.1 - 0.21 12.0 0.1 24 5.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein adh_short PF00106.20 CDO71112.1 - 2e-35 122.1 0.5 2.6e-35 121.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO71112.1 - 2.1e-24 86.6 0.0 2.7e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO71112.1 - 3.9e-19 69.0 0.1 5.5e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO71112.1 - 4.5e-05 23.0 0.0 8.8e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CDO71112.1 - 7.5e-05 22.4 0.2 0.0002 21.0 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CDO71112.1 - 0.029 14.3 0.5 0.085 12.8 0.3 1.8 1 1 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 CDO71112.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF765 PF05570.6 CDO71112.1 - 9 6.3 7.0 12 6.0 0.7 2.4 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) ADH_N PF08240.7 CDO71113.1 - 4.3e-30 103.6 1.4 7.7e-30 102.8 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO71113.1 - 2.5e-21 75.5 0.1 5.3e-21 74.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO71113.1 - 2.9e-06 28.1 0.0 7.9e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CDO71113.1 - 0.0017 17.9 0.1 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 CDO71113.1 - 0.013 16.0 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CDO71113.1 - 0.017 15.6 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 CDO71113.1 - 0.025 13.7 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CDO71113.1 - 0.046 13.1 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MTS PF05175.9 CDO71113.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain GST_N_2 PF13409.1 CDO71114.1 - 3e-43 145.6 0.0 2e-20 72.5 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO71114.1 - 1.1e-30 105.3 0.1 3e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO71114.1 - 7.8e-16 57.8 0.0 4.5e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO71114.1 - 3.8e-10 40.1 0.0 0.0011 19.4 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CDO71114.1 - 7.5e-10 38.8 0.1 0.0098 16.0 0.0 4.1 2 2 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Rota_NSP4 PF01452.11 CDO71114.1 - 0.045 13.1 0.4 0.84 8.9 0.0 2.2 2 0 0 2 2 2 0 Rotavirus non structural protein p450 PF00067.17 CDO71115.1 - 1.6e-58 198.3 0.0 3.7e-58 197.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CDO71116.1 - 7.1e-47 159.9 0.0 2.9e-29 101.9 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 CDO71117.1 - 3.3e-55 187.4 0.0 6.1e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF3967 PF13152.1 CDO71117.1 - 0.12 12.0 0.2 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) p450 PF00067.17 CDO71118.1 - 1.1e-52 179.1 0.0 1.4e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CDO71119.1 - 2.9e-47 161.2 0.0 2.9e-45 154.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Ndufs5 PF10200.4 CDO71120.1 - 4.1e-05 23.4 0.7 5e-05 23.2 0.5 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.5 CDO71120.1 - 5e-05 22.9 3.8 7.2e-05 22.4 2.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 CDO71120.1 - 0.0051 16.8 1.5 0.0076 16.2 1.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.3 CDO71120.1 - 0.013 15.5 3.5 0.043 13.9 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) CHCH PF06747.8 CDO71120.1 - 0.12 12.3 5.1 2.1 8.3 0.3 2.2 1 1 1 2 2 2 0 CHCH domain PADR1 PF08063.7 CDO71120.1 - 0.19 11.1 3.2 3.4 7.1 0.0 2.5 2 1 1 3 3 3 0 PADR1 (NUC008) domain ubiquitin PF00240.18 CDO71121.1 - 4.3e-15 54.8 0.0 6.6e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CDO71121.1 - 9.6e-08 31.6 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 CDO71121.1 - 0.0019 18.7 0.1 0.0033 17.9 0.1 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD OPT PF03169.10 CDO71122.1 - 2.7e-93 313.5 39.7 3.2e-93 313.2 27.6 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_61 PF03443.9 CDO71125.1 - 4.1e-62 209.8 0.1 5.8e-62 209.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Wzt_C PF14524.1 CDO71125.1 - 0.097 12.3 0.0 0.19 11.3 0.0 1.5 2 0 0 2 2 2 0 Wzt C-terminal domain Myb_Cef PF11831.3 CDO71126.1 - 0.69 9.0 7.1 0.83 8.8 4.9 1.1 1 0 0 1 1 1 0 pre-mRNA splicing factor component hNIFK_binding PF12196.3 CDO71126.1 - 2.8 7.4 5.8 1.2 8.5 2.1 1.8 1 1 1 2 2 2 0 FHA Ki67 binding domain of hNIFK PWI PF01480.12 CDO71127.1 - 9.7e-28 96.0 0.0 1.4e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 PWI domain Gly-rich_Ago1 PF12764.2 CDO71127.1 - 0.0021 18.6 2.9 0.0052 17.4 2.0 1.6 1 0 0 1 1 1 1 Glycine-rich region of argonaut SET PF00856.23 CDO71128.1 - 3.1e-14 53.5 0.1 5.9e-11 42.9 0.0 2.4 2 0 0 2 2 2 2 SET domain MR_MLE_C PF13378.1 CDO71129.1 - 9.9e-31 105.9 0.0 1.9e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 CDO71129.1 - 1.1e-22 80.1 0.0 2.9e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 CDO71129.1 - 0.0006 20.2 0.1 0.043 14.3 0.0 2.9 2 1 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain SET PF00856.23 CDO71130.1 - 4.4e-12 46.5 0.1 1.9e-10 41.2 0.1 2.4 1 1 0 1 1 1 1 SET domain GST_N_3 PF13417.1 CDO71131.1 - 1.3e-13 50.9 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO71131.1 - 3.5e-08 33.3 0.0 1.3e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO71131.1 - 0.00018 21.5 0.0 0.00065 19.8 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO71131.1 - 0.011 15.6 0.3 0.026 14.3 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ATP_bind_1 PF03029.12 CDO71132.1 - 1.2e-71 240.9 0.0 1.5e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 CDO71132.1 - 0.069 13.0 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDO71132.1 - 0.13 13.0 7.4 0.056 14.2 1.8 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CDO71132.1 - 0.19 11.6 0.7 1.9 8.4 0.5 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.24 CDO71133.1 - 4.7e-15 55.4 0.0 2.1e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO71133.1 - 1.2e-10 41.0 0.1 3e-09 36.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DivIC PF04977.10 CDO71133.1 - 0.42 10.1 3.2 0.96 8.9 2.2 1.5 1 0 0 1 1 1 0 Septum formation initiator Cut8_N PF14482.1 CDO71133.1 - 0.47 10.4 3.9 0.23 11.4 0.8 1.9 2 0 0 2 2 2 0 Cut8 proteasome-binding domain BUD22 PF09073.5 CDO71133.1 - 3.2 6.7 15.7 0.092 11.8 6.4 1.6 2 0 0 2 2 2 0 BUD22 CPSF_A PF03178.10 CDO71135.1 - 6e-71 239.1 0.0 1.7e-70 237.6 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 CDO71135.1 - 4.4e-06 25.1 0.0 3e-05 22.3 0.0 2.2 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GST_N_3 PF13417.1 CDO71136.1 - 2.8e-08 33.8 0.1 9.1e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO71136.1 - 0.0005 20.0 0.0 0.0012 18.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO71136.1 - 0.00052 19.8 0.3 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO71136.1 - 0.00097 19.5 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 CDO71136.1 - 0.0077 16.2 0.3 0.11 12.5 0.1 2.6 2 1 1 3 3 3 1 Glutaredoxin GST_C PF00043.20 CDO71136.1 - 0.043 13.7 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain bZIP_1 PF00170.16 CDO71137.1 - 6.8e-07 29.1 6.7 4e-06 26.6 4.6 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CDO71137.1 - 7e-07 28.9 9.6 5.2e-06 26.1 2.9 2.4 1 1 1 2 2 2 2 Basic region leucine zipper PAP2 PF01569.16 CDO71138.1 - 1.9e-16 59.9 3.4 9.7e-16 57.6 2.3 2.3 1 1 0 1 1 1 1 PAP2 superfamily BNIP3 PF06553.7 CDO71138.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 BNIP3 MtrB PF05440.7 CDO71138.1 - 0.27 11.3 0.1 0.27 11.3 0.1 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF4646 PF15496.1 CDO71139.1 - 3e-31 108.0 0.0 5e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Metallophos PF00149.23 CDO71141.1 - 1.6e-40 138.6 0.2 2.2e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UNC-50 PF05216.8 CDO71142.1 - 3e-77 258.9 13.0 3.7e-77 258.6 9.0 1.1 1 0 0 1 1 1 1 UNC-50 family WW PF00397.21 CDO71143.1 - 9.4e-08 31.7 1.0 2.3e-07 30.5 0.7 1.7 1 0 0 1 1 1 1 WW domain PGM_PMM_I PF02878.11 CDO71145.1 - 2.2e-37 127.6 0.2 3.8e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CDO71145.1 - 4e-25 88.0 0.0 7.3e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CDO71145.1 - 2.6e-14 53.3 0.0 8.1e-14 51.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CDO71145.1 - 1.9e-07 30.9 0.0 5.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2236 PF09995.4 CDO71146.1 - 5.2e-18 65.2 1.7 5.2e-18 65.2 1.2 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) TPR_11 PF13414.1 CDO71147.1 - 6.3e-19 67.3 10.1 4.5e-11 42.2 0.1 4.1 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.1 CDO71147.1 - 1.7e-13 50.8 4.5 7.7e-08 32.8 0.0 3.6 1 1 2 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CDO71147.1 - 4.4e-13 48.9 7.5 3.8e-07 29.9 0.1 3.4 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CDO71147.1 - 5.8e-11 41.4 13.6 2.5e-07 30.0 0.0 5.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDO71147.1 - 1.4e-10 40.5 0.2 0.0086 16.1 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CDO71147.1 - 8.6e-09 35.6 3.4 0.00057 20.1 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO71147.1 - 1.1e-08 34.9 9.7 6e-06 26.4 0.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDO71147.1 - 1.2e-08 34.1 12.4 2e-07 30.3 0.0 4.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO71147.1 - 6.5e-07 28.6 2.3 0.0073 16.0 0.0 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDO71147.1 - 0.00016 21.9 0.1 0.026 14.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO71147.1 - 0.00025 20.6 5.2 0.0065 16.1 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CDO71147.1 - 0.0005 19.2 0.9 0.00078 18.5 0.6 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 CDO71147.1 - 0.0011 18.8 4.5 0.28 11.1 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat Apc5 PF12862.2 CDO71147.1 - 0.0027 17.5 0.1 0.0067 16.2 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 Apc3 PF12895.2 CDO71147.1 - 0.0096 16.0 3.1 0.23 11.6 0.1 2.6 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 CDO71147.1 - 0.015 15.3 1.0 0.21 11.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.2 CDO71147.1 - 0.024 14.4 1.5 6.6 6.5 0.1 3.0 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) Exonuc_VII_S PF02609.11 CDO71147.1 - 0.059 13.1 2.0 7.7 6.3 0.0 3.4 3 0 0 3 3 3 0 Exonuclease VII small subunit TPR_5 PF12688.2 CDO71147.1 - 0.094 12.7 1.0 8.3 6.4 0.1 2.6 2 0 0 2 2 2 0 Tetratrico peptide repeat Fis1_TPR_C PF14853.1 CDO71147.1 - 0.1 12.4 0.0 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF1771 PF08590.5 CDO71147.1 - 0.95 9.5 8.1 1.5 8.8 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1771) MIT PF04212.13 CDO71147.1 - 3.2 7.7 9.9 6.6 6.6 0.1 3.6 2 2 2 4 4 4 0 MIT (microtubule interacting and transport) domain Shisa PF13908.1 CDO71148.1 - 0.065 13.4 6.7 1.1 9.3 4.6 2.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator CorA PF01544.13 CDO71150.1 - 3.8e-11 42.5 4.7 6.3e-11 41.8 3.2 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2800 PF10926.3 CDO71150.1 - 0.012 14.7 0.1 0.016 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) MFS_1 PF07690.11 CDO71150.1 - 0.02 13.6 0.1 0.029 13.1 0.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2130 PF09903.4 CDO71150.1 - 0.028 13.1 0.2 0.037 12.7 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Syntaxin PF00804.20 CDO71150.1 - 0.032 14.4 0.8 0.054 13.6 0.1 1.8 2 0 0 2 2 2 0 Syntaxin AAA PF00004.24 CDO71152.1 - 1.6e-44 151.3 0.0 2.6e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CDO71152.1 - 2.5e-08 34.0 0.0 5.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CDO71152.1 - 8.6e-07 28.7 0.0 4.8e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDO71152.1 - 4.1e-06 26.9 0.5 1.2e-05 25.4 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 CDO71152.1 - 5e-06 26.6 0.3 0.00029 20.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CDO71152.1 - 5.4e-05 24.0 0.1 0.00015 22.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO71152.1 - 5.6e-05 22.8 0.1 0.00015 21.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CDO71152.1 - 7.6e-05 21.8 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CDO71152.1 - 0.00031 20.2 0.0 0.00076 18.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CDO71152.1 - 0.00076 18.3 0.0 0.0016 17.2 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 CDO71152.1 - 0.00087 19.1 0.0 0.0032 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CDO71152.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDO71152.1 - 0.0022 17.1 0.0 0.0045 16.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 CDO71152.1 - 0.0034 17.3 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CDO71152.1 - 0.0035 16.9 0.0 0.0078 15.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CDO71152.1 - 0.0048 16.1 0.0 0.063 12.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 CDO71152.1 - 0.006 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CDO71152.1 - 0.0094 16.2 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CDO71152.1 - 0.015 14.4 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 CDO71152.1 - 0.015 14.7 0.1 0.085 12.3 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.1 CDO71152.1 - 0.021 14.2 0.1 0.077 12.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 CDO71152.1 - 0.021 13.7 0.0 0.044 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 CDO71152.1 - 0.023 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CDO71152.1 - 0.033 14.3 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CDO71152.1 - 0.042 13.5 0.0 0.55 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 CDO71152.1 - 0.046 13.7 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CDO71152.1 - 0.051 12.4 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 CDO71152.1 - 0.097 11.5 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DivIC PF04977.10 CDO71152.1 - 0.25 10.8 4.8 0.62 9.5 3.3 1.6 1 0 0 1 1 1 0 Septum formation initiator AAA_12 PF13087.1 CDO71155.1 - 9.7e-49 165.4 0.0 1.3e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDO71155.1 - 2.2e-29 102.7 0.0 4e-14 52.7 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 CDO71155.1 - 5.4e-12 45.6 0.0 1.3e-10 41.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDO71155.1 - 8e-11 41.5 0.0 2.7e-10 39.8 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain UvrD_C PF13361.1 CDO71155.1 - 1.1e-05 25.0 0.2 0.00031 20.3 0.2 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CDO71155.1 - 0.00022 20.6 0.0 0.0067 15.7 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 CDO71155.1 - 0.00075 18.7 0.0 0.048 12.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.10 CDO71155.1 - 0.0014 18.4 0.0 0.0044 16.8 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 CDO71155.1 - 0.013 14.6 0.0 0.046 12.8 0.0 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 CDO71155.1 - 0.02 15.0 0.0 0.17 12.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CDO71155.1 - 0.027 14.4 0.0 0.089 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.9 CDO71155.1 - 0.061 12.2 0.0 9 5.1 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase T2SE PF00437.15 CDO71155.1 - 0.068 12.0 0.0 0.16 10.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.1 CDO71155.1 - 0.092 12.8 0.1 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 CDO71155.1 - 0.092 11.7 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 CDO71155.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 CDO71155.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_12 PF13087.1 CDO71156.1 - 5.2e-46 156.5 0.0 6.9e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDO71156.1 - 4.8e-14 52.5 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CDO71156.1 - 2e-06 27.5 0.0 6.3e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.1 CDO71156.1 - 5.6e-05 22.7 0.1 0.0023 17.4 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CDO71156.1 - 0.0065 16.0 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Inhibitor_G39P PF11417.3 CDO71157.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P Peptidase_M24 PF00557.19 CDO71158.1 - 3.7e-35 121.4 0.0 5.9e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CDO71158.1 - 1.6e-07 31.8 0.1 0.015 15.7 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Mg_trans_NIPA PF05653.9 CDO71159.1 - 3.9e-99 331.4 10.8 5.8e-99 330.8 7.5 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CDO71159.1 - 1.5e-05 25.1 2.5 1.5e-05 25.1 1.7 3.2 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CDO71159.1 - 0.0048 16.9 3.3 0.0048 16.9 2.3 3.7 2 2 0 3 3 3 1 EamA-like transporter family Ribosomal_S7 PF00177.16 CDO71160.1 - 7.8e-26 90.4 0.0 1.1e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Aldedh PF00171.17 CDO71161.1 - 1.7e-85 287.0 0.0 2.1e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.17 CDO71162.1 - 1.6e-51 175.3 0.0 2.2e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF647 PF04884.9 CDO71162.1 - 1.9e-48 164.8 4.3 3.1e-47 160.8 2.9 2.1 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis BBE PF08031.7 CDO71163.1 - 8.9e-07 28.7 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 CDO71164.1 - 4.9e-10 39.0 0.5 1e-09 37.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CDO71164.1 - 1e-08 34.9 0.1 2e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_16 PF10294.4 CDO71165.1 - 0.0022 17.4 0.0 0.068 12.6 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 CDO71165.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Aldo_ket_red PF00248.16 CDO71166.1 - 3.7e-23 81.7 0.0 8.3e-21 74.0 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Thioredox_DsbH PF03190.10 CDO71167.1 - 2.1e-70 235.6 0.0 3.5e-70 234.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 CDO71167.1 - 6.9e-11 42.0 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CDO71167.1 - 0.036 14.2 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain APH PF01636.18 CDO71168.1 - 1.8e-14 54.0 0.0 4e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CDO71168.1 - 0.00072 18.9 0.1 0.16 11.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Pkinase_Tyr PF07714.12 CDO71168.1 - 0.0028 16.7 0.0 0.042 12.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Fructosamin_kin PF03881.9 CDO71168.1 - 0.0041 16.1 0.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 2 Fructosamine kinase Choline_kinase PF01633.15 CDO71168.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 CDO71168.1 - 0.039 13.0 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 CDO71168.1 - 0.19 10.8 0.1 18 4.3 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain HLH PF00010.21 CDO71171.1 - 1.8e-19 69.1 0.1 1.1e-18 66.5 0.0 2.5 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain NAD_binding_10 PF13460.1 CDO71173.1 - 2.2e-06 27.7 0.0 5.9e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CDO71173.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase LBR_tudor PF09465.5 CDO71173.1 - 0.022 14.3 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain NAD_binding_4 PF07993.7 CDO71173.1 - 0.025 13.4 0.1 0.32 9.8 0.0 2.3 1 1 2 3 3 3 0 Male sterility protein Semialdhyde_dh PF01118.19 CDO71173.1 - 0.054 13.7 0.0 0.079 13.2 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 CDO71173.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Sin3_corepress PF08295.7 CDO71174.1 - 5.1e-36 122.4 0.8 1.9e-35 120.6 0.1 2.3 3 0 0 3 3 3 1 Sin3 family co-repressor PAH PF02671.16 CDO71174.1 - 8.2e-30 102.1 0.8 1.1e-14 53.8 0.0 3.7 3 1 0 3 3 3 3 Paired amphipathic helix repeat IF4E PF01652.13 CDO71175.1 - 3.6e-48 163.2 0.0 4.9e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1102 PF06510.6 CDO71175.1 - 0.034 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) Glyco_hydro_18 PF00704.23 CDO71176.1 - 1.3e-64 218.8 4.5 1.7e-64 218.4 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 CDO71176.1 - 0.037 13.1 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Med22 PF06179.7 CDO71177.1 - 3.7e-13 49.4 4.4 5.1e-13 48.9 3.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex UCH PF00443.24 CDO71178.1 - 3.1e-44 151.1 0.0 5e-44 150.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDO71178.1 - 1.3e-14 54.3 0.1 1e-06 28.4 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUF4617 PF15395.1 CDO71179.1 - 4.7 5.1 6.2 5.3 4.9 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) F1F0-ATPsyn_F PF10791.4 CDO71180.1 - 6.8e-26 90.3 0.0 7.6e-26 90.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 CDO71180.1 - 0.019 15.0 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f SHMT PF00464.14 CDO71181.1 - 3.3e-171 569.0 0.0 3.8e-171 568.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CDO71181.1 - 0.00049 19.3 0.0 0.0018 17.5 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CDO71181.1 - 0.019 13.9 0.0 0.047 12.6 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class I and II COesterase PF00135.23 CDO71182.1 - 4.7e-57 193.9 0.0 5.6e-56 190.3 0.0 2.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CDO71182.1 - 0.00093 18.8 0.0 0.064 12.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1749 PF08538.5 CDO71182.1 - 0.0015 17.4 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) SRP19 PF01922.12 CDO71183.1 - 7.4e-25 87.3 0.0 1.1e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein PP2C_C PF07830.8 CDO71183.1 - 0.022 14.8 0.1 0.049 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF2360 PF10152.4 CDO71183.1 - 7.5 6.8 6.4 1.2 9.4 1.4 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Aldo_ket_red PF00248.16 CDO71184.1 - 3.1e-72 242.7 0.0 3.5e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4449 PF14613.1 CDO71185.1 - 9.1e-28 97.2 0.3 9.1e-28 97.2 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Aminotran_1_2 PF00155.16 CDO71186.1 - 3.7e-58 197.2 0.0 4.2e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CDO71186.1 - 0.016 13.4 0.0 0.039 12.2 0.0 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.2 CDO71186.1 - 0.13 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase zf-MYND PF01753.13 CDO71187.1 - 6.3e-10 38.7 13.9 6.3e-10 38.7 9.6 1.8 2 0 0 2 2 2 1 MYND finger TPR_17 PF13431.1 CDO71187.1 - 0.045 13.9 0.0 1.2 9.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 CDO71189.1 - 8.1e-67 218.9 28.0 2.9e-16 58.6 0.5 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CDO71189.1 - 1.7e-06 27.4 0.1 1.3 8.6 0.0 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 CDO71189.1 - 1.5e-05 23.9 0.0 6.7 5.3 0.0 4.1 1 1 3 4 4 4 4 Nup133 N terminal like PD40 PF07676.7 CDO71189.1 - 0.0059 16.2 0.3 5.3 6.8 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 CDO71189.1 - 0.017 14.8 4.1 0.68 9.6 0.1 3.7 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term PAH PF02671.16 CDO71190.1 - 0.0028 17.2 0.2 0.0042 16.6 0.1 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat DUF4336 PF14234.1 CDO71191.1 - 1.6e-10 40.6 0.1 4.7e-05 22.7 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) PIF1 PF05970.9 CDO71194.1 - 3.7e-59 200.5 0.0 1.6e-32 112.9 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 CDO71194.1 - 1e-43 149.1 0.1 1.9e-43 148.3 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus zf-C2H2_4 PF13894.1 CDO71194.1 - 5.8e-09 35.6 19.6 0.013 15.8 0.5 7.0 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO71194.1 - 1.7e-08 34.2 14.5 0.085 13.2 0.2 6.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type AAA_19 PF13245.1 CDO71194.1 - 3.6e-06 26.6 0.6 1.5e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Part of AAA domain zf-RING_5 PF14634.1 CDO71194.1 - 1.1e-05 25.1 11.7 1.1e-05 25.1 8.1 4.3 5 1 0 5 5 3 1 zinc-RING finger domain zf-met PF12874.2 CDO71194.1 - 3e-05 24.0 12.1 2.8 8.2 0.0 6.2 6 0 0 6 6 6 2 Zinc-finger of C2H2 type AAA_30 PF13604.1 CDO71194.1 - 3.9e-05 23.3 0.0 7.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain zf-RING_2 PF13639.1 CDO71194.1 - 0.00076 19.2 12.2 0.00076 19.2 8.5 4.7 4 1 1 5 5 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDO71194.1 - 0.0013 18.7 12.3 0.0013 18.7 8.6 3.8 2 1 2 4 4 2 1 Zinc finger, C3HC4 type (RING finger) AAA_16 PF13191.1 CDO71194.1 - 0.0055 16.7 0.3 0.091 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain zf-C2H2_6 PF13912.1 CDO71194.1 - 0.016 15.1 9.8 2.8 7.9 0.3 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger DUF2791 PF10923.3 CDO71194.1 - 0.049 12.2 0.0 0.08 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) NACHT PF05729.7 CDO71194.1 - 0.053 13.1 0.0 0.46 10.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain zf-C2H2_jaz PF12171.3 CDO71194.1 - 0.058 13.5 19.2 2.4 8.3 0.0 6.2 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding AAA_22 PF13401.1 CDO71194.1 - 0.072 13.2 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-C3HC4_4 PF15227.1 CDO71194.1 - 0.33 10.8 11.8 2.5 8.0 8.2 2.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.9 CDO71194.1 - 0.63 9.5 6.5 1 8.9 0.2 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_6 PF14835.1 CDO71194.1 - 7.4 6.4 14.3 2.2 8.1 4.3 3.3 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Cu-oxidase PF00394.17 CDO71195.1 - 2.8e-41 141.0 0.1 6.7e-36 123.5 0.1 3.4 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 CDO71195.1 - 3.5e-26 91.3 3.2 1.3e-24 86.2 0.5 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CDO71195.1 - 5.7e-18 64.7 0.4 5.7e-18 64.7 0.3 4.0 4 1 0 5 5 5 1 Multicopper oxidase EGF_2 PF07974.8 CDO71196.1 - 2.4 8.4 10.4 8.8 6.5 4.3 2.8 3 0 0 3 3 3 0 EGF-like domain Hira PF07569.6 CDO71197.1 - 1.5e-50 171.4 0.0 4.7e-50 169.8 0.0 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 CDO71197.1 - 1.5e-35 119.7 13.6 5.2e-09 35.6 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 CDO71197.1 - 1.3e-07 31.5 6.4 1.3e-07 31.5 4.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO71197.1 - 6.1e-07 28.9 5.8 6.1e-07 28.9 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO71197.1 - 1.3e-06 28.1 6.4 1.3e-06 28.1 4.4 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 CDO71197.1 - 1.2e-05 24.9 5.9 1.2e-05 24.9 4.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CDO71197.1 - 1.7e-05 24.4 5.6 4.2e-05 23.1 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CDO71197.1 - 1.8e-05 24.5 6.8 6e-05 22.8 4.7 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CDO71197.1 - 0.00018 21.0 4.8 0.00018 21.0 3.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_jaz PF12171.3 CDO71197.1 - 0.013 15.5 0.3 0.013 15.5 0.2 2.7 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding zf-rbx1 PF12678.2 CDO71197.1 - 0.031 14.3 1.0 0.072 13.2 0.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 CDO71197.1 - 0.033 13.9 1.0 0.079 12.7 0.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-met PF12874.2 CDO71197.1 - 0.12 12.6 0.2 0.12 12.6 0.1 3.2 4 0 0 4 4 2 0 Zinc-finger of C2H2 type NOA36 PF06524.7 CDO71197.1 - 0.13 11.5 4.2 0.22 10.7 2.9 1.2 1 0 0 1 1 1 0 NOA36 protein zf-C2H2_4 PF13894.1 CDO71197.1 - 0.45 10.9 0.1 0.45 10.9 0.0 3.5 4 1 0 4 4 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CDO71197.1 - 0.52 10.3 3.2 2.6 8.0 0.0 2.9 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO71197.1 - 0.55 10.6 6.4 1.9 9.0 0.1 3.1 3 0 0 3 3 2 0 Zinc finger, C2H2 type zf-PARP PF00645.13 CDO71198.1 - 3.7e-43 145.6 3.6 1.5e-20 73.2 0.1 2.4 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Ribosomal_S26e PF01283.14 CDO71199.1 - 1.9e-51 173.1 10.6 2.3e-51 172.8 7.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 CDO71199.1 - 0.029 14.7 0.7 0.4 11.1 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF1918 PF08940.6 CDO71199.1 - 0.04 13.2 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) SCF PF02404.10 CDO71200.1 - 2.5 7.2 4.7 3.9 6.5 3.1 1.5 1 1 0 1 1 1 0 Stem cell factor HLH PF00010.21 CDO71201.1 - 0.0055 16.3 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain YL1 PF05764.8 CDO71201.1 - 0.011 15.4 1.0 0.026 14.1 0.7 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 CDO71201.1 - 0.51 8.1 4.9 0.88 7.4 3.4 1.3 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.1 CDO71201.1 - 0.52 10.4 4.8 0.65 10.1 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF500 PF04366.7 CDO71202.1 - 3.1e-36 123.5 0.2 5.2e-36 122.8 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_2 PF07653.12 CDO71202.1 - 3.6e-16 58.3 0.1 2.3e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CDO71202.1 - 7.2e-16 57.3 0.1 1.6e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CDO71202.1 - 6.9e-14 51.1 0.1 1.7e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain PHF5 PF03660.9 CDO71203.1 - 5.4e-51 171.1 7.9 6.1e-51 170.9 5.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PHD PF00628.24 CDO71203.1 - 0.022 14.4 4.7 0.022 14.4 3.2 2.5 1 1 1 2 2 2 0 PHD-finger DZR PF12773.2 CDO71203.1 - 0.21 11.4 14.8 0.04 13.7 4.7 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 CDO71203.1 - 0.68 9.7 14.7 2.9 7.6 0.4 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DDE_Tnp_4 PF13359.1 CDO71204.1 - 1e-22 80.3 0.0 1.3e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CDO71204.1 - 0.0035 16.7 0.1 0.0059 16.0 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO71204.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.16 CDO71204.1 - 0.024 14.1 0.2 0.089 12.3 0.1 1.8 1 1 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 CDO71205.1 - 0.013 16.1 0.0 0.034 14.7 0.0 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pap_E4 PF02711.9 CDO71205.1 - 4.9 8.0 5.6 7.2 7.4 0.8 2.6 2 1 0 2 2 2 0 E4 protein DDE_Tnp_4 PF13359.1 CDO71206.1 - 1e-22 80.3 0.0 1.3e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CDO71206.1 - 0.0035 16.7 0.1 0.0059 16.0 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO71206.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.16 CDO71206.1 - 0.024 14.1 0.2 0.089 12.3 0.1 1.8 1 1 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 CDO71207.1 - 2.1e-05 25.0 0.3 4.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CDO71207.1 - 0.00023 21.2 0.4 0.00062 19.8 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pap_E4 PF02711.9 CDO71207.1 - 2.2 9.1 5.2 4 8.3 0.7 2.7 2 1 0 2 2 2 0 E4 protein AA_permease_2 PF13520.1 CDO71208.1 - 9.8e-31 106.7 28.9 8.9e-17 60.7 11.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 CDO71208.1 - 2.4e-10 39.3 24.0 2.4e-05 22.8 5.5 2.1 1 1 1 2 2 2 2 Amino acid permease DUF2040 PF09745.4 CDO71209.1 - 1.6e-35 121.6 28.6 1.6e-35 121.6 19.8 3.9 3 2 2 5 5 5 2 Coiled-coil domain-containing protein 55 (DUF2040) CAF-1_p150 PF11600.3 CDO71209.1 - 5.6 6.2 61.8 1.7 8.0 12.7 2.3 2 1 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RRM_1 PF00076.17 CDO71210.1 - 6.8e-11 41.6 0.1 3.3e-09 36.2 0.1 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO71210.1 - 4e-08 33.1 0.1 1.9e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO71210.1 - 1.6e-06 27.8 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIID-18kDa PF02269.11 CDO71211.1 - 1.3e-20 73.0 0.1 1.7e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit ECR1_N PF14382.1 CDO71212.1 - 6.4e-14 50.9 0.0 1.3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 CDO71212.1 - 0.0017 18.2 0.0 0.057 13.3 0.0 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 DUF4211 PF13926.1 CDO71213.1 - 3.1e-29 101.3 0.0 7.8e-29 100.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DUF86 PF01934.12 CDO71213.1 - 0.096 12.3 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF86 DNA_methylase PF00145.12 CDO71215.1 - 1.9e-40 138.9 0.0 3.1e-38 131.7 0.0 3.0 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 CDO71215.1 - 2.4e-18 66.0 0.0 2.7e-10 40.0 0.1 2.5 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 CDO71215.1 - 3.2e-09 36.6 0.0 5.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Met_10 PF02475.11 CDO71215.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DDE_3 PF13358.1 CDO71216.1 - 0.0023 17.7 0.2 0.0062 16.2 0.2 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease Dimer_Tnp_hAT PF05699.9 CDO71217.1 - 6e-14 51.4 0.0 1.4e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-TAZ PF02135.11 CDO71217.1 - 0.047 13.7 1.7 0.11 12.5 1.2 1.6 1 0 0 1 1 1 0 TAZ zinc finger OST3_OST6 PF04756.8 CDO71218.1 - 2.3e-16 59.7 0.8 3.3e-16 59.2 0.5 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 CDO71218.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4149 PF13664.1 CDO71218.1 - 0.068 13.2 4.0 3.1 7.9 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF1796 PF08795.5 CDO71218.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Sec16_C PF12931.2 CDO71219.1 - 2.4e-66 224.3 0.0 3.2e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CDO71219.1 - 1.5e-29 102.3 0.0 5.4e-29 100.5 0.0 2.0 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PUF PF00806.14 CDO71220.1 - 7.2e-66 214.1 1.4 4.8e-08 32.0 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat SapB_2 PF03489.12 CDO71220.1 - 0.2 11.7 0.5 2 8.5 0.1 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 2 Myelin-PO_C PF10570.4 CDO71220.1 - 0.22 11.5 1.3 0.86 9.7 0.1 2.6 3 0 0 3 3 3 0 Myelin-PO cytoplasmic C-term p65 binding region Elf1 PF05129.8 CDO71221.1 - 1.8e-27 94.8 0.4 2.2e-27 94.5 0.3 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.7 CDO71221.1 - 0.0057 16.7 0.7 0.0082 16.2 0.5 1.2 1 0 0 1 1 1 1 CHY zinc finger Cytochrom_c3_2 PF14537.1 CDO71221.1 - 0.055 13.8 0.2 0.073 13.4 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c3 DRP PF06044.7 CDO71221.1 - 0.13 11.2 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Dam-replacing family Kinesin PF00225.18 CDO71222.1 - 2.1e-110 368.5 0.0 2.5e-109 365.0 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 CDO71222.1 - 3.5e-06 27.2 0.2 3.5e-06 27.2 0.1 4.3 4 2 2 6 6 6 1 Kinesin-associated microtubule-binding Vps55 PF04133.9 CDO71223.1 - 4.3e-42 142.6 2.1 4.8e-42 142.4 1.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 TRAPPC9-Trs120 PF08626.6 CDO71224.1 - 4.9e-89 299.1 0.0 7.4e-63 212.4 0.0 3.6 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit GMC_oxred_N PF00732.14 CDO71225.1 - 2.5e-57 194.3 0.0 3.7e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO71225.1 - 5.3e-35 120.8 0.0 1.4e-34 119.4 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase PI3_PI4_kinase PF00454.22 CDO71225.1 - 1.2e-33 116.5 0.0 1.9e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NAD_binding_8 PF13450.1 CDO71225.1 - 7.1e-05 22.7 0.1 0.00026 20.9 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO71225.1 - 0.0001 21.3 0.0 0.00021 20.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CDO71225.1 - 0.00087 18.4 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 CDO71225.1 - 0.0036 16.2 0.1 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CDO71225.1 - 0.0074 15.1 0.2 0.012 14.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 CDO71225.1 - 0.081 12.6 0.2 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CDO71225.1 - 0.085 12.7 0.2 0.21 11.4 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO71225.1 - 0.14 12.6 0.1 0.42 11.0 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO71225.1 - 0.52 8.7 0.0 0.85 8.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Glyco_transf_15 PF01793.11 CDO71226.1 - 4.7e-136 453.0 7.8 4.1e-120 400.6 3.8 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase TFIIA PF03153.8 CDO71227.1 - 0.095 12.5 16.0 0.1 12.4 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDO71227.1 - 0.25 9.5 29.1 0.3 9.2 20.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CDO71227.1 - 1.1 8.5 31.8 1.7 7.9 22.0 1.4 1 0 0 1 1 1 0 Vta1 like Spore_coat_CotO PF14153.1 CDO71228.1 - 1.5 8.1 10.8 0.085 12.2 3.7 1.8 2 0 0 2 2 2 0 Spore coat protein CotO Sec62 PF03839.11 CDO71228.1 - 8.7 5.6 10.7 17 4.7 7.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 USP7_ICP0_bdg PF12436.3 CDO71229.1 - 6.9e-86 287.5 1.5 2.2e-85 285.9 0.5 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 CDO71229.1 - 1.8e-69 233.4 3.8 4.7e-67 225.5 1.6 3.3 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 CDO71229.1 - 1.3e-56 191.7 0.2 2.4e-56 190.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDO71229.1 - 4.5e-31 108.3 0.0 8e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 CDO71229.1 - 1.9e-07 31.3 0.6 1.2e-05 25.5 0.0 3.7 3 2 1 4 4 4 1 MATH domain Sec66 PF09802.4 CDO71230.1 - 5.8e-52 175.8 0.0 7.3e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Citrate_synt PF00285.16 CDO71231.1 - 2.3e-102 342.3 0.0 3.1e-102 341.9 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase XH PF03469.9 CDO71231.1 - 0.065 12.8 0.1 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 XH domain B56 PF01603.15 CDO71233.1 - 3.3e-172 572.6 9.2 4e-172 572.4 6.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DNA_primase_lrg PF04104.9 CDO71234.1 - 2.1e-82 276.3 0.0 3.1e-82 275.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CDP-OH_P_transf PF01066.16 CDO71234.1 - 1.6e-11 44.3 3.7 3.5e-11 43.3 2.6 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase SMC_Nse1 PF07574.8 CDO71235.1 - 1.2e-30 106.6 1.4 5.5e-29 101.2 0.9 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CDO71235.1 - 4.4e-08 32.9 11.1 7.7e-08 32.2 7.7 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 CDO71235.1 - 1e-05 25.2 10.3 2e-05 24.3 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 CDO71235.1 - 0.00055 19.2 5.5 0.0011 18.2 3.8 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.1 CDO71235.1 - 0.0091 15.6 8.7 0.015 14.9 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 CDO71235.1 - 0.013 15.5 3.3 0.027 14.4 2.3 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_2 PF13923.1 CDO71235.1 - 0.014 15.4 11.2 0.024 14.6 7.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDO71235.1 - 0.032 14.3 4.8 0.069 13.2 3.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Baculo_RING PF05883.6 CDO71235.1 - 0.036 13.8 3.0 0.075 12.8 2.1 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Paf1 PF03985.8 CDO71235.1 - 0.05 12.3 3.4 0.07 11.8 2.3 1.2 1 0 0 1 1 1 0 Paf1 zf-HC5HC2H PF13771.1 CDO71235.1 - 0.067 13.3 8.5 0.21 11.7 5.9 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 CDO71235.1 - 0.25 11.1 12.4 0.43 10.3 8.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 CDO71235.1 - 0.26 10.9 8.0 0.66 9.7 5.6 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 CDO71235.1 - 0.62 9.6 12.9 0.17 11.4 6.9 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain C1_1 PF00130.17 CDO71235.1 - 1.5 8.5 8.6 0.88 9.3 4.3 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.3 CDO71235.1 - 3 7.8 8.8 9.7 6.2 6.1 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain AAA PF00004.24 CDO71236.1 - 5.5e-37 126.9 0.0 1.6e-36 125.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDO71236.1 - 4.2e-06 26.8 4.1 0.0011 18.9 0.0 4.4 3 1 1 5 5 4 1 AAA ATPase domain AAA_17 PF13207.1 CDO71236.1 - 2.3e-05 25.1 0.0 0.00022 22.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CDO71236.1 - 0.00013 21.8 0.0 0.0029 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CDO71236.1 - 0.00033 20.8 0.0 0.021 14.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO71236.1 - 0.00055 19.6 0.1 0.0017 18.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CDO71236.1 - 0.00062 19.5 0.1 0.0032 17.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CDO71236.1 - 0.00097 18.5 3.0 2.2 7.6 0.1 4.0 3 1 0 4 4 4 2 AAA domain AAA_28 PF13521.1 CDO71236.1 - 0.001 19.0 0.1 0.046 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CDO71236.1 - 0.0018 18.6 0.1 0.12 12.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CDO71236.1 - 0.013 14.5 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus UPF0079 PF02367.12 CDO71236.1 - 0.013 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 CDO71236.1 - 0.027 13.8 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein SNF2_N PF00176.18 CDO71236.1 - 0.042 12.6 0.0 0.08 11.7 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_11 PF13086.1 CDO71236.1 - 0.044 13.3 0.0 0.13 11.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 CDO71236.1 - 0.056 12.3 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.8 CDO71236.1 - 0.11 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 CDO71236.1 - 0.21 11.7 0.0 0.55 10.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IPT PF01745.11 CDO71236.1 - 0.23 10.5 0.0 2.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Rad17 PF03215.10 CDO71236.1 - 0.3 9.7 0.0 0.45 9.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein CDP-OH_P_transf PF01066.16 CDO71237.1 - 2.9e-20 72.4 2.0 6.8e-20 71.2 1.4 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase FAD_binding_3 PF01494.14 CDO71238.1 - 2.6e-15 56.3 0.0 4.2e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 CDO71238.1 - 0.024 13.4 0.1 0.11 11.2 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase AT_hook PF02178.14 CDO71239.1 - 5.4e-05 22.4 55.6 0.023 14.3 4.0 4.6 4 0 0 4 4 4 4 AT hook motif PRKCSH PF07915.8 CDO71240.1 - 2e-12 47.7 0.1 4.5e-12 46.5 0.0 1.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 CDO71240.1 - 0.028 13.8 0.0 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Pkinase PF00069.20 CDO71241.1 - 4.9e-57 193.0 0.0 2.2e-55 187.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71241.1 - 2.1e-27 95.8 0.0 3.7e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO71241.1 - 0.0058 16.3 0.1 0.015 15.0 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CDO71241.1 - 0.024 13.6 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DEAD PF00270.24 CDO71243.1 - 8.8e-42 142.4 0.0 1.2e-40 138.8 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO71243.1 - 2.3e-24 85.0 0.3 6.7e-24 83.5 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO71243.1 - 0.014 15.1 0.9 0.09 12.6 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DivIC PF04977.10 CDO71243.1 - 1.4 8.4 14.7 4.9 6.6 10.2 2.0 1 0 0 1 1 1 0 Septum formation initiator MIP-T3 PF10243.4 CDO71243.1 - 8.8 4.6 22.8 15 3.9 15.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DNA_ligase_IV PF11411.3 CDO71245.1 - 0.064 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 DNA ligase IV Pkinase PF00069.20 CDO71246.1 - 4.7e-50 170.1 0.1 6.4e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71246.1 - 6.9e-27 94.1 0.0 9.5e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CDO71246.1 - 3.5e-05 23.2 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CDO71246.1 - 0.00023 20.2 0.1 0.00034 19.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDO71246.1 - 0.0074 16.0 0.0 0.022 14.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Histone PF00125.19 CDO71248.1 - 2.1e-13 50.1 0.0 3.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TRAM_LAG1_CLN8 PF03798.11 CDO71250.1 - 9.4e-32 110.1 24.9 9.4e-32 110.1 17.2 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CDO71250.1 - 3.3e-16 58.5 0.0 6.6e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 CDO71251.1 - 2.9e-31 108.5 23.9 2.9e-31 108.5 16.6 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CDO71251.1 - 1.4e-15 56.5 0.2 2.9e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 TRAM1-like protein RNase_T PF00929.19 CDO71252.1 - 3.3e-15 56.7 0.4 3.7e-09 37.0 0.0 2.8 2 1 1 3 3 3 2 Exonuclease CHORD PF04968.7 CDO71252.1 - 0.014 15.6 6.6 0.25 11.6 4.8 2.5 2 1 0 2 2 2 0 CHORD Clat_adaptor_s PF01217.15 CDO71253.1 - 3.1e-57 192.2 4.7 3.6e-57 192.0 3.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GVQW PF13900.1 CDO71254.1 - 0.0037 17.2 0.3 0.0074 16.2 0.2 1.5 1 0 0 1 1 1 1 Putative binding domain Iso_dh PF00180.15 CDO71255.1 - 8.3e-79 265.0 0.0 1e-78 264.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_6 PF12697.2 CDO71256.1 - 5.4e-05 23.1 0.1 0.00023 21.1 0.0 2.1 2 2 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO71256.1 - 0.028 14.1 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Amidohydro_2 PF04909.9 CDO71257.1 - 5.4e-40 137.6 6.2 9e-24 84.4 0.6 2.1 2 0 0 2 2 2 2 Amidohydrolase adh_short PF00106.20 CDO71258.1 - 7.4e-31 107.3 0.0 1.3e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO71258.1 - 1.1e-13 51.4 0.0 1.5e-13 51.0 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO71258.1 - 2.1e-13 50.3 0.1 4.3e-13 49.3 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CDO71258.1 - 4.8e-05 23.4 0.0 8.8e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Transket_pyr PF02779.19 CDO71259.1 - 1.2e-47 161.6 0.1 2.8e-47 160.4 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CDO71259.1 - 6.8e-40 135.8 0.3 6.8e-40 135.8 0.2 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Histidinol_dh PF00815.15 CDO71260.1 - 1.1e-123 412.8 7.3 3.1e-54 184.1 1.7 3.2 1 1 2 3 3 3 3 Histidinol dehydrogenase PRA-CH PF01502.13 CDO71260.1 - 6.9e-26 89.6 0.0 1.6e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 CDO71260.1 - 2.6e-08 34.0 0.0 6.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 CDO71260.1 - 0.0034 17.2 0.0 0.0082 16.0 0.0 1.7 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Piwi PF02171.12 CDO71261.1 - 7.1e-71 238.6 0.0 2.5e-67 226.9 0.0 2.2 1 1 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 CDO71261.1 - 2e-15 55.8 0.1 5.6e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 CDO71261.1 - 1.3e-14 53.6 0.0 2.5e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Piwi PF02171.12 CDO71262.1 - 4.1e-76 255.8 0.0 1.3e-75 254.2 0.0 1.7 1 1 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 CDO71262.1 - 1.6e-16 59.3 0.0 4.9e-16 57.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 CDO71262.1 - 7.4e-13 47.9 0.0 1.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Mito_carr PF00153.22 CDO71264.1 - 3.1e-68 225.5 3.3 6e-24 83.5 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CDO71264.1 - 3.6e-05 23.7 0.2 0.00016 21.7 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CDO71264.1 - 0.00057 18.9 0.3 0.019 14.2 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CDO71264.1 - 0.0014 18.3 0.0 0.039 13.8 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CDO71264.1 - 0.017 14.4 1.1 0.071 12.4 0.1 2.4 2 0 0 2 2 2 0 EF hand Herpes_BBRF1 PF04793.7 CDO71265.1 - 0.039 12.7 1.5 0.075 11.7 1.0 1.4 1 0 0 1 1 1 0 BRRF1-like protein DUF3584 PF12128.3 CDO71265.1 - 7.4 3.7 28.7 12 3.0 19.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 CDO71266.1 - 0.00058 19.4 2.1 0.00058 19.4 1.5 3.1 1 1 1 2 2 2 1 Intermediate filament protein ADIP PF11559.3 CDO71266.1 - 0.0034 17.2 16.2 0.014 15.3 3.1 2.6 2 1 0 2 2 2 2 Afadin- and alpha -actinin-Binding Streptin-Immun PF11083.3 CDO71266.1 - 0.021 14.7 1.5 4.4 7.3 0.1 3.0 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein Reo_sigmaC PF04582.7 CDO71266.1 - 0.036 13.2 11.4 0.16 11.1 0.5 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Kinetocho_Slk19 PF12709.2 CDO71266.1 - 0.1 12.6 0.3 0.1 12.6 0.2 3.3 2 1 1 3 3 3 0 Central kinetochore-associated Atg14 PF10186.4 CDO71266.1 - 0.12 11.3 20.1 0.054 12.4 0.7 3.4 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 CDO71266.1 - 0.21 11.9 15.4 8 6.9 0.1 4.9 3 1 2 5 5 5 0 SlyX Spc7 PF08317.6 CDO71266.1 - 0.22 10.1 16.2 0.16 10.5 1.4 2.9 1 1 1 3 3 3 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 CDO71266.1 - 0.26 11.0 16.7 0.18 11.5 1.2 3.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.10 CDO71266.1 - 0.42 10.5 20.1 1.8 8.5 3.8 2.5 1 1 1 2 2 2 0 Fez1 Rho_Binding PF08912.6 CDO71266.1 - 0.47 10.7 7.6 1.2 9.4 0.1 3.4 2 1 0 2 2 2 0 Rho Binding ERM PF00769.14 CDO71266.1 - 1 8.8 21.3 0.17 11.4 3.5 3.0 1 1 2 3 3 3 0 Ezrin/radixin/moesin family IncA PF04156.9 CDO71266.1 - 1.4 8.5 28.3 31 4.1 9.5 3.0 1 1 1 2 2 2 0 IncA protein Prominin PF05478.6 CDO71266.1 - 1.6 6.1 10.7 0.018 12.6 0.7 2.0 2 1 1 3 3 3 0 Prominin UPF0184 PF03670.8 CDO71266.1 - 2.2 8.5 5.5 21 5.4 0.1 3.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) Hemerythrin PF01814.18 CDO71266.1 - 2.9 8.0 7.5 1.3 9.2 0.1 3.1 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain Pox_A_type_inc PF04508.7 CDO71266.1 - 3.6 7.6 11.3 5.1 7.1 0.1 5.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat CK_II_beta PF01214.13 CDO71267.1 - 1.8e-76 255.7 0.0 2.6e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ribosomal_L36e PF01158.13 CDO71267.1 - 1.2e-25 89.3 1.1 9e-25 86.5 0.7 2.1 1 1 0 1 1 1 1 Ribosomal protein L36e DUF390 PF04094.9 CDO71267.1 - 0.42 8.6 6.0 0.59 8.1 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) SNARE_assoc PF09335.6 CDO71268.1 - 4.4e-17 62.4 4.0 4.4e-17 62.4 2.8 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein CRCB PF02537.10 CDO71269.1 - 4.8e-31 107.0 17.2 1.7e-19 69.8 3.1 2.5 2 1 0 2 2 2 2 CrcB-like protein adh_short PF00106.20 CDO71270.1 - 1.4e-08 34.8 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 60KD_IMP PF02096.15 CDO71272.1 - 2.7e-20 72.8 0.4 5.7e-20 71.8 0.3 1.5 1 1 0 1 1 1 1 60Kd inner membrane protein Bac_rhodopsin PF01036.13 CDO71272.1 - 0.035 13.4 0.7 0.097 11.9 0.4 1.6 1 1 0 1 1 1 0 Bacteriorhodopsin-like protein Seryl_tRNA_N PF02403.17 CDO71272.1 - 0.063 13.3 0.4 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_L6e PF01159.14 CDO71273.1 - 2e-38 130.9 0.1 3.2e-38 130.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 CDO71273.1 - 2.9e-07 30.2 0.1 2.9e-07 30.2 0.1 2.1 3 0 0 3 3 3 1 Ribosomal protein L6, N-terminal domain HAD_2 PF13419.1 CDO71274.1 - 3.7e-18 66.3 0.0 4.2e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDO71274.1 - 0.0028 18.1 0.0 0.0028 18.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UPF0183 PF03676.9 CDO71275.1 - 3.2e-09 35.8 0.0 4.1e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Apt1 PF10351.4 CDO71276.1 - 2.6e-76 257.3 0.6 5.2e-76 256.3 0.4 1.5 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 CDO71276.1 - 8e-46 156.4 0.0 1.1e-32 113.0 0.0 2.6 3 0 0 3 3 3 2 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 CDO71276.1 - 4.8e-42 143.5 0.0 8.8e-42 142.6 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DNA_pol_E_B PF04042.11 CDO71276.1 - 1.2e-39 135.7 0.1 2.4e-39 134.7 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF2405 PF10293.4 CDO71276.1 - 1.4e-22 80.1 0.0 4.7e-22 78.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CDO71276.1 - 1.7e-15 57.2 0.0 7.9e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Lactonase PF10282.4 CDO71277.1 - 5.6e-06 25.6 0.0 0.00069 18.8 0.0 2.8 3 0 0 3 3 3 2 Lactonase, 7-bladed beta-propeller DUF2985 PF11204.3 CDO71279.1 - 3.7e-25 87.4 3.5 7e-25 86.5 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) RXT2_N PF08595.6 CDO71279.1 - 0.079 12.7 0.3 0.079 12.7 0.2 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Meth_synt_2 PF01717.13 CDO71280.1 - 2.3e-144 480.3 0.0 8.9e-140 465.2 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CDO71280.1 - 2e-121 405.0 0.0 3.5e-107 358.2 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 CDO71280.1 - 0.0017 17.7 5.4 0.02 14.3 0.7 2.8 2 0 0 2 2 2 2 Short C-terminal domain ADH_N PF08240.7 CDO71281.1 - 3.2e-31 107.2 0.3 4.9e-31 106.7 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO71281.1 - 5.1e-20 71.3 0.0 8.1e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO71281.1 - 4.6e-06 27.5 0.0 7.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Gly_transf_sug PF04488.10 CDO71282.1 - 7.9e-21 74.3 0.1 1.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CDO71282.1 - 0.019 13.4 6.1 0.17 10.3 0.5 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 CDO71282.1 - 0.1 11.7 0.1 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein PIN_4 PF13638.1 CDO71283.1 - 1.6e-20 73.5 0.0 2.5e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 PIN domain CTD_bind PF04818.8 CDO71284.1 - 0.0029 17.8 0.0 0.0078 16.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DAP3 PF10236.4 CDO71284.1 - 0.073 11.9 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ribosomal_L6 PF00347.18 CDO71285.1 - 3.2e-29 101.2 4.9 1.8e-15 57.1 0.9 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 ICMT PF04140.9 CDO71286.1 - 2.2e-27 95.1 1.2 4.4e-27 94.1 0.8 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO71286.1 - 1.8e-13 50.5 1.3 4.1e-13 49.3 0.9 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.6 CDO71286.1 - 2.8e-06 26.8 1.9 5.1e-06 25.9 1.3 1.4 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.7 CDO71286.1 - 0.004 16.4 1.0 0.0063 15.8 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GTP_EFTU PF00009.22 CDO71287.1 - 8.5e-49 165.5 0.0 1.4e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CDO71287.1 - 5.5e-16 58.2 0.0 3.3e-15 55.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CDO71287.1 - 7.7e-16 57.7 0.0 1.8e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CDO71287.1 - 2.9e-06 27.3 0.0 5.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CDO71287.1 - 0.0015 18.4 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 CDO71287.1 - 0.13 11.3 0.0 0.45 9.5 0.0 1.8 1 1 0 1 1 1 0 AIG1 family MFS_1 PF07690.11 CDO71289.1 - 5.8e-33 114.0 16.9 5.4e-30 104.3 10.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 CDO71289.1 - 0.0015 17.3 0.5 0.0031 16.2 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TRI12 PF06609.8 CDO71289.1 - 0.0061 14.8 2.3 0.0099 14.1 1.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TruD PF01142.13 CDO71290.1 - 6.4e-66 222.5 0.0 9.1e-63 212.1 0.0 3.2 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) OMPdecase PF00215.19 CDO71291.1 - 2.8e-74 249.3 0.0 3.5e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family eRF1_1 PF03463.10 CDO71292.1 - 1.4e-39 134.6 0.0 2.5e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 CDO71292.1 - 1.9e-22 79.6 0.0 3.9e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 CDO71292.1 - 1.6e-19 70.5 0.0 2.5e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Thioredoxin PF00085.15 CDO71293.1 - 0.0029 17.2 0.1 0.0054 16.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Not3 PF04065.10 CDO71293.1 - 0.05 12.8 0.9 0.072 12.3 0.6 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component THOC7 PF05615.8 CDO71293.1 - 0.12 12.6 2.0 0.39 10.9 1.3 1.7 1 1 1 2 2 2 0 Tho complex subunit 7 FAD_binding_7 PF03441.9 CDO71294.1 - 1.5e-86 290.0 0.6 2.8e-86 289.1 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CDO71294.1 - 7.7e-26 90.7 0.5 4.1e-13 49.4 0.0 2.4 1 1 1 2 2 2 2 DNA photolyase DUF1793 PF08760.6 CDO71295.1 - 1.6e-61 207.0 0.7 3.4e-61 206.0 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF1793 PF08760.6 CDO71296.1 - 3.1e-45 154.0 4.1 2.6e-44 151.0 2.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1793) PRP38_assoc PF12871.2 CDO71297.1 - 0.016 15.7 20.7 0.03 14.8 14.3 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 CDO71297.1 - 0.38 10.4 15.5 0.7 9.6 10.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) HR1 PF02185.11 CDO71297.1 - 1.2 8.9 6.9 0.17 11.6 1.7 1.9 2 0 0 2 2 2 0 Hr1 repeat TMF_DNA_bd PF12329.3 CDO71297.1 - 1.2 8.9 8.4 2.6 7.9 0.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FliJ PF02050.11 CDO71297.1 - 4.1 7.4 7.6 0.26 11.3 1.4 1.7 2 0 0 2 2 2 0 Flagellar FliJ protein Glyco_hydro_18 PF00704.23 CDO71299.1 - 5.4e-05 22.8 0.0 7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF605 PF04652.11 CDO71299.1 - 6.1 6.1 14.1 8.3 5.6 9.8 1.2 1 0 0 1 1 1 0 Vta1 like DUF1488 PF07369.6 CDO71300.1 - 0.018 14.8 0.1 0.043 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) Myb_DNA-bind_2 PF08914.6 CDO71301.1 - 0.085 12.6 3.8 0.18 11.5 0.2 2.6 3 0 0 3 3 3 0 Rap1 Myb domain ThiF PF00899.16 CDO71302.1 - 1.4e-49 167.3 0.0 2.2e-28 98.7 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 CDO71302.1 - 1.6e-42 142.9 3.4 7.5e-28 95.9 0.1 3.7 3 0 0 3 3 3 3 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 CDO71302.1 - 8e-35 119.7 3.2 1.3e-23 83.4 0.1 2.8 2 1 1 3 3 3 2 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 CDO71302.1 - 2.5e-25 87.6 0.8 3.5e-21 74.3 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site End_beta_barrel PF12195.3 CDO71302.1 - 0.17 11.6 0.1 2.5 7.8 0.0 2.4 1 1 1 2 2 2 0 Beta barrel domain of bacteriophage endosialidase ATP_bind_4 PF01902.12 CDO71303.1 - 6.7e-33 113.8 0.0 1.1e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 CDO71303.1 - 2.1e-21 75.9 0.0 1.2e-10 41.1 0.0 2.8 2 1 0 2 2 2 2 Endoribonuclease L-PSP MFS_1 PF07690.11 CDO71304.1 - 2.7e-11 42.7 25.7 1.7e-10 40.1 16.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDO71304.1 - 2.2e-10 39.5 7.4 2.2e-10 39.5 5.1 2.8 3 1 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 CDO71304.1 - 0.1 12.3 4.0 0.7 9.7 0.0 3.1 2 0 0 2 2 2 0 MFS_1 like family Spore_YhaL PF14147.1 CDO71304.1 - 0.19 11.2 1.3 17 4.9 0.0 2.8 2 0 0 2 2 2 0 Sporulation protein YhaL Ank_2 PF12796.2 CDO71305.1 - 2.7e-37 126.9 0.2 2.6e-16 59.7 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDO71305.1 - 9.8e-26 89.6 2.2 1e-12 48.1 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 CDO71305.1 - 1.1e-22 78.6 0.1 1.6e-08 33.9 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CDO71305.1 - 4.2e-18 64.9 0.4 1.1e-08 35.0 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO71305.1 - 1.1e-15 56.0 0.1 3.7e-05 23.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat zf-Mss51 PF13824.1 CDO71306.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Cyclin PF08613.6 CDO71307.1 - 6.2e-08 33.1 0.0 1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin DUF3402 PF11882.3 CDO71308.1 - 5.9e-121 404.3 0.0 8.1e-73 245.8 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.8 CDO71308.1 - 4.7e-42 143.8 2.4 1.2e-26 93.2 2.2 2.2 1 1 1 2 2 2 2 N1221-like protein Diphthamide_syn PF01866.12 CDO71309.1 - 4.7e-87 292.0 0.0 7.8e-33 114.0 0.2 4.0 4 0 0 4 4 4 4 Putative diphthamide synthesis protein Patched PF02460.13 CDO71310.1 - 2.5e-64 217.5 12.8 3.8e-37 127.6 0.3 3.7 3 1 0 3 3 3 3 Patched family Sterol-sensing PF12349.3 CDO71310.1 - 7e-47 158.7 13.7 5.3e-25 87.6 0.1 3.5 3 0 0 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 CDO71310.1 - 5.1e-05 20.9 6.4 5.1e-05 20.9 3.2 1.7 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Folate_rec PF03024.9 CDO71310.1 - 0.0006 19.4 1.3 0.0012 18.5 0.9 1.4 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.10 CDO71310.1 - 9.9 4.7 30.5 0.036 12.7 0.9 4.2 3 1 0 3 3 3 0 MMPL family RNR_inhib PF08591.5 CDO71311.1 - 7.2e-05 23.6 0.4 0.00016 22.5 0.2 1.7 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor GCIP PF13324.1 CDO71311.1 - 0.039 13.1 0.1 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting zf-C2H2_4 PF13894.1 CDO71312.1 - 0.0002 21.4 16.3 0.068 13.5 1.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO71312.1 - 0.0023 18.1 18.4 0.006 16.8 0.7 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO71312.1 - 0.016 15.4 14.1 1.2 9.5 1.1 3.8 3 0 0 3 3 3 0 Zinc-finger double domain DUF629 PF04780.7 CDO71312.1 - 0.76 8.2 2.8 1.1 7.6 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) CIAPIN1 PF05093.8 CDO71313.1 - 1e-30 105.7 5.0 1.8e-30 104.9 3.5 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF3716 PF12511.3 CDO71313.1 - 8.7 6.0 9.5 2.7 7.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) RseC_MucC PF04246.7 CDO71313.1 - 9.8 5.7 9.3 0.57 9.7 1.3 2.4 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Fork_head PF00250.13 CDO71316.1 - 1.8e-29 101.6 0.0 3e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Fork head domain Tim17 PF02466.14 CDO71317.1 - 0.077 13.0 3.2 0.28 11.2 1.9 2.1 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.20 CDO71318.1 - 5.3e-63 212.5 0.5 1.2e-62 211.4 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71318.1 - 1.6e-28 99.4 0.7 2e-28 99.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.19 CDO71318.1 - 2.3e-14 53.6 0.1 2.3e-14 53.6 0.1 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.25 CDO71318.1 - 1.2e-07 31.4 0.2 0.0023 17.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.1 CDO71318.1 - 1.4e-06 27.5 0.0 3.5e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CDO71318.1 - 0.0024 17.6 1.0 0.006 16.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO71318.1 - 0.021 14.4 2.0 0.043 13.3 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Suc_Fer-like PF06999.7 CDO71319.1 - 6.9e-13 49.1 0.3 1.4e-12 48.1 0.2 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like APH PF01636.18 CDO71320.1 - 0.00086 19.1 0.1 0.0023 17.7 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CDO71321.1 - 9.2e-63 211.8 0.0 2.1e-40 138.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71321.1 - 8.3e-29 100.4 0.0 1.6e-23 83.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 CDO71321.1 - 2.9e-14 53.0 0.1 5.3e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 CDO71321.1 - 1.5e-07 30.6 0.1 0.00045 19.2 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 CDO71321.1 - 0.00031 20.5 0.1 0.0025 17.6 0.1 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CDO71321.1 - 0.008 15.2 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CDO71321.1 - 0.099 11.9 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 CDO71321.1 - 0.15 10.9 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 IFT46_B_C PF12317.3 CDO71321.1 - 2.2 7.5 5.4 0.39 10.0 0.7 1.9 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Ribosomal_S18 PF01084.15 CDO71322.1 - 9.9e-14 50.9 0.2 1.9e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Mesothelin PF06060.7 CDO71322.1 - 0.11 10.5 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) JAB PF01398.16 CDO71323.1 - 8.7e-35 118.9 0.4 1.4e-34 118.2 0.3 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CDO71323.1 - 6.5e-29 100.3 1.7 1.9e-28 98.8 1.2 1.8 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CDO71323.1 - 9.7e-09 34.7 0.0 1.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FMO-like PF00743.14 CDO71325.1 - 2.3e-23 82.2 0.0 8e-23 80.4 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CDO71325.1 - 3.4e-23 82.7 0.0 7.2e-23 81.7 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CDO71325.1 - 3.6e-11 42.5 0.0 9.6e-10 37.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CDO71325.1 - 3.4e-10 40.1 0.0 1.5e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO71325.1 - 3e-07 30.7 0.0 0.15 12.4 0.0 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO71325.1 - 0.00076 19.2 0.0 0.16 11.7 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 CDO71325.1 - 0.0017 17.4 0.0 0.091 11.8 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 CDO71325.1 - 0.0017 18.4 0.0 0.091 12.8 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 CDO71325.1 - 0.014 15.4 0.1 0.14 12.2 0.0 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 CDO71325.1 - 0.03 14.3 0.1 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.17 CDO71325.1 - 0.12 11.2 0.0 6.4 5.5 0.0 2.9 3 1 0 3 3 3 0 Glucose inhibited division protein A FMO-like PF00743.14 CDO71326.1 - 8.5e-24 83.6 0.0 4.3e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CDO71326.1 - 9.7e-23 81.2 0.0 2.8e-22 79.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CDO71326.1 - 1.8e-08 33.7 0.0 4e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CDO71326.1 - 7.7e-06 25.9 0.0 6.1e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CDO71326.1 - 0.0068 16.5 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Vps52 PF04129.7 CDO71327.1 - 7.1e-41 140.2 0.1 1.2e-14 53.7 0.0 3.0 3 0 0 3 3 3 3 Vps52 / Sac2 family BRCT PF00533.21 CDO71329.1 - 8e-06 25.9 0.0 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ribophorin_I PF04597.9 CDO71331.1 - 8.2e-91 304.6 0.0 8.1e-84 281.6 0.0 2.2 2 0 0 2 2 2 2 Ribophorin I Ribosomal_L22 PF00237.14 CDO71331.1 - 1.1e-19 70.3 0.8 1.9e-19 69.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e GILT PF03227.11 CDO71332.1 - 1.6e-11 44.0 1.5 2e-11 43.7 0.1 1.8 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Prok-E2_A PF14457.1 CDO71332.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family A Cid2 PF09774.4 CDO71333.1 - 1.8e-19 70.3 0.8 2.1e-19 70.1 0.5 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 zf-H2C2_5 PF13909.1 CDO71334.1 - 0.018 15.2 2.2 0.026 14.7 0.7 1.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Kelch_3 PF13415.1 CDO71335.1 - 9.5e-15 54.2 12.4 0.01 15.9 0.0 6.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CDO71335.1 - 1.9e-13 49.9 14.0 0.0017 18.0 0.0 7.3 8 1 0 8 8 8 3 Galactose oxidase, central domain Kelch_1 PF01344.20 CDO71335.1 - 7.8e-10 38.1 1.7 0.14 11.7 0.1 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 CDO71335.1 - 3.7e-09 36.3 2.8 0.086 13.0 0.0 5.3 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 CDO71335.1 - 1.3e-08 34.5 1.6 0.085 12.8 0.1 4.5 3 0 0 3 3 3 2 Kelch motif Cytochrom_B561 PF03188.11 CDO71335.1 - 0.2 11.4 4.2 2.7 7.8 0.3 2.3 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Plasmodium_Vir PF05795.6 CDO71335.1 - 0.23 10.6 0.2 0.34 10.0 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RAP1 PF07218.6 CDO71335.1 - 6.2 4.7 8.2 8.7 4.2 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HSP90 PF00183.13 CDO71337.1 - 6.5e-116 387.8 6.1 7.7e-116 387.5 4.2 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CDO71337.1 - 1.9e-11 43.7 0.0 4.2e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CDO71337.1 - 2.7e-09 36.7 0.0 5.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase COMPASS-Shg1 PF05205.7 CDO71337.1 - 0.0063 16.7 0.0 0.043 14.0 0.0 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 SSF PF00474.12 CDO71338.1 - 2.5e-24 85.6 17.3 4.8e-24 84.7 12.0 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family FF PF01846.14 CDO71339.1 - 1.9e-42 142.9 18.1 6.7e-11 41.9 0.0 6.4 5 1 0 5 5 5 5 FF domain WW PF00397.21 CDO71339.1 - 1.3e-08 34.4 12.0 3.1e-08 33.3 2.7 3.3 4 0 0 4 4 4 2 WW domain Peroxidase_2 PF01328.12 CDO71340.1 - 1.3e-28 99.6 0.0 2.2e-28 98.8 0.0 1.3 1 1 0 1 1 1 1 Peroxidase, family 2 MFS_1 PF07690.11 CDO71341.1 - 1.6e-27 96.1 25.2 1.1e-26 93.4 17.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily RasGAP_C PF03836.10 CDO71342.1 - 8.3e-40 135.7 2.0 8.3e-40 135.7 1.4 2.5 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 CDO71342.1 - 2.8e-35 121.7 0.0 2.8e-35 121.7 0.0 2.7 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 CDO71342.1 - 1.9e-20 70.4 67.9 0.0015 18.0 0.2 14.0 13 0 0 13 13 13 11 IQ calmodulin-binding motif CH PF00307.26 CDO71342.1 - 7.1e-09 35.6 0.0 2.2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain Sipho_Gp157 PF05565.6 CDO71342.1 - 0.0021 17.6 0.1 0.011 15.3 0.1 2.2 2 0 0 2 2 2 1 Siphovirus Gp157 Spc97_Spc98 PF04130.8 CDO71343.1 - 1.3e-93 314.1 0.0 4.2e-58 197.0 0.0 2.4 1 1 1 2 2 2 2 Spc97 / Spc98 family CrtC PF07143.6 CDO71343.1 - 0.13 11.5 0.1 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Hydroxyneurosporene synthase (CrtC) E1-E2_ATPase PF00122.15 CDO71344.1 - 2e-45 154.5 0.5 5.1e-45 153.2 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CDO71344.1 - 1.1e-33 117.4 0.1 2.2e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDO71344.1 - 8e-13 48.9 0.0 1.8e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CDO71344.1 - 2e-11 43.8 0.0 5.2e-09 36.1 0.0 2.7 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 CDO71344.1 - 0.00054 19.6 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CDO71344.1 - 0.17 12.0 0.0 3.2 7.9 0.0 2.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF4149 PF13664.1 CDO71344.1 - 4 7.5 7.6 0.35 10.9 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) E1-E2_ATPase PF00122.15 CDO71345.1 - 4.2e-44 150.3 0.0 4.2e-44 150.3 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase HMA PF00403.21 CDO71345.1 - 1.2e-41 140.6 0.1 1.6e-11 44.1 0.0 5.0 4 1 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 CDO71345.1 - 2e-38 132.9 0.3 4.3e-38 131.8 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDO71345.1 - 1.2e-17 64.6 0.0 2.5e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDO71345.1 - 0.00057 19.5 0.1 0.0021 17.6 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Toxin-deaminase PF14424.1 CDO71345.1 - 0.00076 19.4 0.2 1.6 8.7 0.0 3.4 3 0 0 3 3 3 1 The BURPS668_1122 family of deaminases His_Phos_2 PF00328.17 CDO71346.1 - 9.4e-86 288.2 0.1 1.9e-85 287.2 0.1 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CDO71346.1 - 5.2e-07 29.3 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain UQ_con PF00179.21 CDO71347.1 - 1.7e-15 56.7 0.1 2.5e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CDO71347.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain AAA_14 PF13173.1 CDO71347.1 - 0.018 14.9 0.1 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain HIG_1_N PF04588.8 CDO71348.1 - 9.7e-06 25.2 3.1 2.2e-05 24.0 2.2 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Cyto_ox_2 PF02322.10 CDO71348.1 - 0.25 10.4 2.3 0.36 9.9 0.5 1.8 2 0 0 2 2 2 0 Cytochrome oxidase subunit II Ferric_reduct PF01794.14 CDO71349.1 - 1.3e-16 60.8 5.1 1.9e-16 60.2 1.8 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CDO71349.1 - 2.3e-11 43.5 0.0 3.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CDO71349.1 - 6.1e-11 42.4 0.0 9.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain PgaD PF13994.1 CDO71349.1 - 0.001 18.5 1.8 0.0011 18.4 0.1 1.9 2 0 0 2 2 2 1 PgaD-like protein NAD_binding_1 PF00175.16 CDO71349.1 - 0.0037 17.8 0.0 0.0078 16.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CDO71350.1 - 1e-17 64.4 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CDO71350.1 - 2.1e-13 50.4 8.5 5.4e-13 49.1 5.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CDO71350.1 - 2.9e-11 43.1 0.0 6.6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 CDO71350.1 - 0.00055 20.4 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain RRM_6 PF14259.1 CDO71351.1 - 1.3e-22 79.5 0.0 1.1e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO71351.1 - 2.1e-21 75.3 0.0 4.9e-10 38.8 0.0 3.9 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO71351.1 - 1.9e-08 34.0 0.0 0.0024 17.6 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO71351.1 - 0.033 13.9 0.0 0.088 12.5 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Hid1 PF12722.2 CDO71351.1 - 9.5 3.7 8.6 12 3.3 6.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ofd1_CTDD PF10637.4 CDO71352.1 - 5.6e-49 166.6 0.6 4.5e-39 134.1 0.3 3.2 2 1 1 3 3 3 3 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CDO71352.1 - 8.7e-16 58.2 0.1 1.2e-13 51.4 0.0 2.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily NOA36 PF06524.7 CDO71352.1 - 8.1 5.5 6.4 12 5.0 4.5 1.1 1 0 0 1 1 1 0 NOA36 protein SelP_N PF04592.9 CDO71353.1 - 0.37 10.1 7.4 0.62 9.3 5.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Tetraspannin PF00335.15 CDO71353.1 - 9.9 5.3 7.5 1.6 7.9 2.4 1.7 1 1 0 1 1 1 0 Tetraspanin family HIG_1_N PF04588.8 CDO71354.1 - 2.1e-05 24.1 0.3 4.3e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region TctB PF07331.6 CDO71354.1 - 0.064 12.9 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Abhydrolase_6 PF12697.2 CDO71355.1 - 4e-31 108.6 0.3 6.5e-31 107.9 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO71355.1 - 9.1e-17 61.3 0.0 8.5e-14 51.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO71355.1 - 2.9e-12 46.5 0.8 4.4e-12 45.9 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO71355.1 - 0.00018 21.2 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 CDO71355.1 - 0.012 14.0 0.0 0.054 11.9 0.0 1.8 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 CDO71355.1 - 0.08 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase FlxA PF14282.1 CDO71356.1 - 0.042 13.7 11.9 0.028 14.3 3.9 2.5 2 0 0 2 2 2 0 FlxA-like protein IncA PF04156.9 CDO71356.1 - 0.23 11.0 18.2 0.44 10.1 8.3 2.4 2 0 0 2 2 2 0 IncA protein AAA_13 PF13166.1 CDO71356.1 - 1.4 7.2 10.4 0.092 11.1 3.8 1.4 2 0 0 2 2 2 0 AAA domain DUF342 PF03961.8 CDO71356.1 - 1.4 7.2 5.8 2.6 6.3 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 CDO71356.1 - 1.4 8.6 16.1 0.77 9.4 3.1 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 TBPIP PF07106.8 CDO71356.1 - 1.6 8.2 13.7 0.13 11.8 5.6 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FemAB PF02388.11 CDO71356.1 - 1.7 7.2 7.4 2.8 6.5 5.1 1.2 1 0 0 1 1 1 0 FemAB family Spc7 PF08317.6 CDO71356.1 - 3.4 6.2 13.2 0.39 9.3 5.4 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3373 PF11853.3 CDO71356.1 - 4.8 5.5 4.3 10 4.5 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) APG6 PF04111.7 CDO71356.1 - 8.3 5.3 17.3 0.35 9.8 7.5 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 Phage_XkdX PF09693.5 CDO71357.1 - 0.39 10.2 0.4 0.6 9.6 0.3 1.2 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Cyt-b5 PF00173.23 CDO71358.1 - 1.5e-24 85.5 0.1 1.9e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sedlin_N PF04628.8 CDO71359.1 - 2e-27 95.6 0.0 2.4e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF2435 PF10363.4 CDO71360.1 - 3.9e-30 103.6 0.1 1.9e-29 101.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 CDO71360.1 - 0.00021 20.7 0.3 0.00065 19.1 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) zf-RING_2 PF13639.1 CDO71361.1 - 9.4e-07 28.5 10.7 2e-06 27.5 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CDO71361.1 - 5.9e-05 22.7 10.1 0.00012 21.7 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CDO71361.1 - 9.3e-05 22.3 11.2 0.00018 21.4 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO71361.1 - 0.00034 20.2 11.1 0.00069 19.2 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO71361.1 - 0.0016 18.0 9.4 0.0033 17.0 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Striatin PF08232.7 CDO71361.1 - 0.0021 18.3 1.6 0.0021 18.3 1.1 2.2 2 0 0 2 2 2 1 Striatin family zf-RING_UBOX PF13445.1 CDO71361.1 - 0.03 14.0 6.5 0.024 14.3 3.2 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CDO71361.1 - 0.046 13.5 10.6 0.13 12.2 7.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Glyco_hydro_85 PF03644.8 CDO71361.1 - 0.049 12.7 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 ERM PF00769.14 CDO71361.1 - 0.065 12.7 10.1 0.13 11.8 7.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SPX PF03105.14 CDO71361.1 - 3.2 7.4 12.0 7.7 6.2 8.3 1.6 1 1 0 1 1 1 0 SPX domain GTP_EFTU PF00009.22 CDO71362.1 - 1.2e-48 165.0 0.0 2.2e-48 164.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CDO71362.1 - 3.4e-25 88.1 0.1 9.9e-25 86.6 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CDO71362.1 - 7.8e-12 45.1 0.3 2.1e-11 43.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CDO71362.1 - 0.00013 21.9 0.0 0.00041 20.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CDO71362.1 - 0.0025 17.4 0.2 0.023 14.3 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 4 PAM2 PF07145.10 CDO71362.1 - 0.0043 16.4 0.6 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 Ataxin-2 C-terminal region Miro PF08477.8 CDO71362.1 - 0.046 14.2 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein G-alpha PF00503.15 CDO71362.1 - 0.047 12.3 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Glyco_hydro_3_C PF01915.17 CDO71362.1 - 0.062 12.8 0.1 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain SH3_9 PF14604.1 CDO71363.1 - 3.4e-38 128.9 8.6 2.3e-14 52.7 0.2 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 CDO71363.1 - 3.9e-38 128.5 5.1 2.7e-15 55.4 0.1 4.2 4 0 0 4 4 4 3 SH3 domain SH3_2 PF07653.12 CDO71363.1 - 5.9e-29 99.3 0.4 4.9e-10 38.7 0.0 4.5 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 CDO71363.1 - 3.2e-08 33.6 3.8 0.0084 16.2 0.2 3.6 3 0 0 3 3 3 3 Bacterial SH3 domain SHD1 PF03983.7 CDO71363.1 - 0.00022 20.7 0.0 0.00065 19.2 0.0 1.8 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 hSH3 PF14603.1 CDO71363.1 - 0.00087 19.2 0.3 0.78 9.7 0.0 2.7 2 0 0 2 2 2 2 Helically-extended SH3 domain DUF1777 PF08648.7 CDO71363.1 - 0.17 11.6 37.5 0.37 10.5 26.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Sec7 PF01369.15 CDO71364.1 - 4.3e-66 222.2 0.0 1.2e-65 220.7 0.0 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CDO71364.1 - 7.4e-54 181.6 5.3 7.4e-54 181.6 3.7 2.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CDO71364.1 - 2.7e-31 106.9 6.7 8.3e-31 105.3 0.1 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) HEAT PF02985.17 CDO71364.1 - 0.033 14.2 3.0 0.79 9.9 0.0 4.8 6 0 0 6 6 6 0 HEAT repeat DUF1539 PF07560.6 CDO71364.1 - 0.058 13.2 1.1 4.8 7.0 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) zf-ZPR1 PF03367.8 CDO71364.1 - 0.07 12.2 0.6 0.64 9.1 0.2 2.3 2 0 0 2 2 2 0 ZPR1 zinc-finger domain DS PF01916.12 CDO71365.1 - 1.4e-140 467.6 0.0 1.6e-140 467.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase SufE PF02657.10 CDO71365.1 - 0.045 13.3 0.0 0.096 12.3 0.0 1.6 1 1 0 1 1 1 0 Fe-S metabolism associated domain 14-3-3 PF00244.15 CDO71366.1 - 3.9e-73 245.4 1.2 4.3e-73 245.2 0.8 1.0 1 0 0 1 1 1 1 14-3-3 protein Glyco_hydro_61 PF03443.9 CDO71367.1 - 9.9e-53 179.1 0.3 1.2e-52 178.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aldo_ket_red PF00248.16 CDO71368.1 - 5.8e-48 163.1 0.0 7.7e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.5 CDO71368.1 - 0.071 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Slx4 endonuclease DUF2052 PF09747.4 CDO71369.1 - 4.2e-07 30.0 15.9 1.2e-06 28.5 11.0 1.8 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF4591 PF15261.1 CDO71369.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) Nucleo_P87 PF07267.6 CDO71369.1 - 0.12 11.0 0.5 0.14 10.7 0.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Abhydrolase_6 PF12697.2 CDO71370.1 - 4.5e-05 23.4 0.4 8.4e-05 22.5 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CDO71370.1 - 0.00016 21.2 0.0 0.00031 20.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CDO71370.1 - 0.00017 21.3 0.1 0.00054 19.7 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CDO71370.1 - 0.005 16.4 0.1 0.012 15.2 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 CDO71370.1 - 0.0056 15.9 0.0 0.077 12.2 0.0 2.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 CDO71370.1 - 0.0077 15.8 0.1 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 CDO71370.1 - 0.025 13.6 0.1 0.16 11.0 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.7 CDO71370.1 - 0.093 12.0 0.1 0.78 9.0 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2974 PF11187.3 CDO71370.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LRR_4 PF12799.2 CDO71371.1 - 6.9e-13 47.9 4.6 0.03 13.9 0.0 7.0 3 2 5 8 8 8 5 Leucine Rich repeats (2 copies) F-box-like PF12937.2 CDO71371.1 - 1.4e-12 47.1 2.5 4.9e-12 45.3 1.8 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 CDO71371.1 - 4.1e-07 29.3 10.4 25 5.3 0.1 9.6 11 0 0 11 11 11 0 Leucine Rich repeat LRR_1 PF00560.28 CDO71371.1 - 5.1e-05 22.7 10.5 2.5 8.4 0.0 7.9 6 3 0 6 6 6 1 Leucine Rich Repeat F-box PF00646.28 CDO71371.1 - 8.5e-05 22.0 0.5 0.0011 18.5 0.5 2.7 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 CDO71371.1 - 0.026 14.2 14.4 1.3 8.8 0.1 5.7 3 2 4 7 7 7 0 Leucine rich repeat LRR_7 PF13504.1 CDO71371.1 - 1.3 9.5 8.9 19 6.0 0.0 6.1 8 0 0 8 8 8 0 Leucine rich repeat DUF4050 PF13259.1 CDO71372.1 - 0.00024 21.0 0.1 0.0005 19.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) LSM PF01423.17 CDO71373.1 - 1.1e-18 66.4 0.4 1.4e-18 66.1 0.3 1.1 1 0 0 1 1 1 1 LSM domain zf-U1 PF06220.7 CDO71374.1 - 1.5e-20 72.4 4.1 2.1e-20 71.9 2.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 CDO71374.1 - 0.016 15.3 2.3 0.028 14.5 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Sua5_yciO_yrdC PF01300.13 CDO71375.1 - 9.1e-53 178.1 0.0 2.1e-52 176.9 0.0 1.6 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 CDO71375.1 - 4.2e-26 91.4 0.0 6.5e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding HMG_box PF00505.14 CDO71376.1 - 1.6e-11 44.3 1.6 4.5e-11 42.8 1.1 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO71376.1 - 0.004 17.4 0.0 0.008 16.5 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain DEAD PF00270.24 CDO71377.1 - 8.1e-26 90.5 0.0 2.2e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO71377.1 - 4.1e-25 87.4 0.1 1.8e-23 82.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Astro_capsid PF03115.9 CDO71377.1 - 2.2 6.4 4.0 2.9 6.0 2.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 CDO71377.1 - 6.7 4.6 12.0 10 3.9 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Mob1_phocein PF03637.12 CDO71379.1 - 1e-53 181.5 0.0 5.6e-47 159.6 0.0 2.0 1 1 1 2 2 2 2 Mob1/phocein family UBX PF00789.15 CDO71379.1 - 0.13 12.3 0.0 4.4 7.4 0.0 2.9 3 0 0 3 3 3 0 UBX domain DJ-1_PfpI PF01965.19 CDO71380.1 - 4.8e-24 84.4 0.2 6.7e-24 84.0 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 CDO71380.1 - 1.6e-10 40.3 0.1 3.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family RRM_1 PF00076.17 CDO71381.1 - 1.6e-18 66.0 0.0 6e-08 32.1 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO71381.1 - 1e-12 47.6 0.0 5.3e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO71381.1 - 2.4e-09 37.0 0.0 0.001 19.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 CDO71381.1 - 0.14 10.0 4.7 0.17 9.8 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.8 CDO71381.1 - 0.62 7.7 6.6 0.81 7.3 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.6 CDO71381.1 - 1.4 8.3 8.7 2 7.8 6.0 1.1 1 0 0 1 1 1 0 PPP4R2 TRAM_LAG1_CLN8 PF03798.11 CDO71382.1 - 6e-46 156.4 25.7 7.8e-46 156.1 17.8 1.1 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 CDO71382.1 - 3.9e-08 32.6 0.0 3.9e-08 32.6 0.0 3.0 4 0 0 4 4 4 1 TRAM1-like protein Snf7 PF03357.16 CDO71383.1 - 8.2e-26 90.4 31.0 2.8e-14 52.8 9.5 2.4 3 0 0 3 3 3 2 Snf7 TRAPP PF04051.11 CDO71383.1 - 0.097 12.1 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component DUF3166 PF11365.3 CDO71383.1 - 0.24 11.8 13.2 1.3 9.5 1.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) Wound_ind PF08186.6 CDO71383.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Wound-inducible basic protein family DUF3138 PF11336.3 CDO71383.1 - 0.49 8.5 3.8 0.13 10.4 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) NIF PF03031.13 CDO71384.1 - 6.8e-50 168.8 0.0 1.1e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MFS_1 PF07690.11 CDO71384.1 - 2.6e-39 134.9 44.1 3.4e-37 127.9 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.1 CDO71385.1 - 1.4e-05 24.7 7.0 0.0067 16.2 4.8 3.1 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDO71385.1 - 0.00044 20.3 1.5 0.016 15.2 1.1 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDO71385.1 - 0.00065 19.3 0.3 0.024 14.2 0.2 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO71385.1 - 0.013 15.1 5.8 0.52 10.0 4.3 3.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CDO71385.1 - 0.18 11.8 10.2 2.8 8.0 3.6 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO71385.1 - 0.21 11.2 6.2 7.4 6.3 2.2 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDO71385.1 - 0.36 10.7 5.0 3.8 7.4 0.0 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CDO71385.1 - 0.39 10.4 3.8 1.2 8.9 1.5 2.5 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 CDO71385.1 - 1.3 8.6 8.5 7 6.2 0.2 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 NOA36 PF06524.7 CDO71385.1 - 1.4 8.1 4.8 2.2 7.4 3.3 1.3 1 0 0 1 1 1 0 NOA36 protein zf-RING_4 PF14570.1 CDO71385.1 - 4.1 7.0 10.2 1.7 8.2 1.7 3.3 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain tRNA-synt_2c PF01411.14 CDO71386.1 - 2.9e-05 22.5 0.0 4.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CDO71386.1 - 0.003 17.4 0.0 0.0087 15.9 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MFS_1 PF07690.11 CDO71387.1 - 6.9e-39 133.5 30.6 2.2e-37 128.5 20.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2 PF00703.16 CDO71388.1 - 1.1e-08 35.5 0.0 3.3e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 CDO71388.1 - 9.7e-05 21.9 0.1 0.00021 20.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 CDO71388.1 - 0.00039 19.4 0.0 0.00063 18.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF2563 PF10817.3 CDO71388.1 - 0.17 12.3 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2563) Ras PF00071.17 CDO71389.1 - 2.7e-44 150.3 1.1 5.1e-44 149.5 0.1 1.7 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CDO71389.1 - 1.3e-13 51.4 0.4 5.2e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CDO71389.1 - 1e-05 24.8 0.0 1.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CDO71389.1 - 2.3e-05 23.9 0.3 3.5e-05 23.3 0.2 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDO71389.1 - 0.0016 18.4 0.1 0.0039 17.1 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDO71389.1 - 0.006 15.8 0.1 0.14 11.4 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 CDO71389.1 - 0.082 12.5 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase PNRC PF15365.1 CDO71389.1 - 0.51 10.3 4.3 1 9.4 3.0 1.4 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Spo12 PF05032.7 CDO71390.1 - 3e-11 42.7 3.4 6.6e-11 41.6 2.4 1.6 1 0 0 1 1 1 1 Spo12 family Chitin_synth_1 PF01644.12 CDO71391.1 - 2.5e-63 212.7 0.1 3.9e-63 212.0 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CDO71391.1 - 5.2e-28 96.5 1.2 9.3e-28 95.7 0.2 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CDO71391.1 - 3e-25 88.6 0.2 1.6e-20 73.0 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CDO71391.1 - 5.4e-12 45.8 0.2 5.4e-12 45.8 0.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CDO71391.1 - 7.1e-08 32.5 0.0 2.3e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GST_C_2 PF13410.1 CDO71392.1 - 2e-05 24.3 0.1 3.9e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO71392.1 - 0.0003 20.7 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO71392.1 - 0.0016 18.9 0.1 0.0028 18.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Molydop_binding PF01568.16 CDO71392.1 - 0.0052 16.5 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain CLPTM1 PF05602.7 CDO71393.1 - 6.4e-133 443.6 0.0 8.2e-133 443.3 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 CDO71393.1 - 0.0013 18.2 0.4 0.0013 18.2 0.2 1.8 2 0 0 2 2 2 1 PQ loop repeat GnsAB PF08178.6 CDO71394.1 - 0.03 13.9 0.5 0.059 13.0 0.4 1.4 1 0 0 1 1 1 0 GnsA/GnsB family MAS20 PF02064.10 CDO71395.1 - 6.6e-18 64.7 4.1 1.4e-16 60.5 2.8 2.5 1 1 0 1 1 1 1 MAS20 protein import receptor SET PF00856.23 CDO71395.1 - 1.4e-08 35.1 0.3 7.7e-07 29.5 0.0 2.9 3 0 0 3 3 3 1 SET domain zf-MYND PF01753.13 CDO71395.1 - 0.093 12.6 0.4 0.093 12.6 0.2 1.9 2 0 0 2 2 2 0 MYND finger AAA PF00004.24 CDO71396.1 - 2.3e-16 60.2 0.0 4.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PGPGW PF09656.5 CDO71397.1 - 0.069 12.4 0.4 0.14 11.5 0.3 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) Sporozoite_P67 PF05642.6 CDO71397.1 - 0.074 10.9 4.6 0.092 10.6 3.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen p450 PF00067.17 CDO71398.1 - 1.6e-56 191.7 0.2 1.9e-55 188.2 0.1 2.3 1 1 0 1 1 1 1 Cytochrome P450 tRNA-synt_1c PF00749.16 CDO71399.1 - 5.3e-105 350.5 0.0 7.2e-105 350.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 CDO71399.1 - 3.7e-30 104.5 0.0 6.2e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 CDO71399.1 - 1.3e-29 103.1 0.0 3.3e-29 101.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 CDO71399.1 - 3.9e-08 33.8 1.6 3.9e-08 33.8 1.1 2.6 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 p450 PF00067.17 CDO71400.1 - 4.3e-48 164.0 0.0 9.2e-36 123.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Bin3 PF06859.7 CDO71401.1 - 1.2e-32 112.1 0.0 1.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_11 PF08241.7 CDO71401.1 - 7.8e-06 26.2 0.0 1.4e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO71401.1 - 2e-05 24.9 0.0 3.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO71401.1 - 2.6e-05 24.0 0.0 3.5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO71401.1 - 2.8e-05 23.7 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO71401.1 - 3.6e-05 24.3 0.0 5.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO71401.1 - 0.023 15.0 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CDO71401.1 - 0.024 14.6 0.0 0.05 13.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 CDO71401.1 - 0.047 12.7 0.0 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HAD_2 PF13419.1 CDO71402.1 - 5.1e-13 49.6 0.0 1.3e-12 48.3 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CDO71402.1 - 1.9e-12 46.6 0.0 3.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CDO71402.1 - 6.6e-08 33.2 0.0 2.2e-07 31.5 0.0 1.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sec15 PF04091.7 CDO71403.1 - 3e-69 233.7 0.0 6e-69 232.7 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Vps51 PF08700.6 CDO71403.1 - 1.6e-07 31.0 2.5 3.1e-07 30.1 0.2 2.8 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 CDO71403.1 - 1.7e-06 28.0 0.4 1.7e-06 28.0 0.3 3.3 3 1 1 4 4 4 1 Golgi transport complex subunit 5 Sec5 PF15469.1 CDO71403.1 - 1.9e-06 27.6 0.5 1.5e-05 24.8 0.0 2.7 3 0 0 3 3 3 1 Exocyst complex component Sec5 Sec8_exocyst PF04048.9 CDO71403.1 - 0.00018 21.1 2.4 0.00018 21.1 1.7 2.7 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 CDO71403.1 - 0.0037 17.1 0.7 0.0037 17.1 0.5 2.9 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 YtzH PF14165.1 CDO71403.1 - 0.19 11.9 5.7 4.4 7.6 0.1 3.6 3 1 0 3 3 3 0 YtzH-like protein Reo_sigmaC PF04582.7 CDO71403.1 - 7.5 5.6 11.4 1.3 8.1 0.7 2.8 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Arf PF00025.16 CDO71404.1 - 1.2e-79 265.6 0.1 1.4e-79 265.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CDO71404.1 - 3.3e-14 52.5 0.0 4e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CDO71404.1 - 7.6e-13 48.1 0.0 8.3e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CDO71404.1 - 3.1e-12 45.8 1.4 3.8e-09 35.7 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CDO71404.1 - 3.7e-11 42.6 0.0 4.5e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CDO71404.1 - 1.8e-09 38.1 0.0 2.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CDO71404.1 - 3.7e-06 26.8 0.0 4.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CDO71404.1 - 0.0068 15.5 0.6 0.014 14.4 0.4 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CDO71404.1 - 0.014 14.8 0.1 0.12 11.8 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CDO71404.1 - 0.056 13.3 0.2 0.14 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CDO71404.1 - 0.11 11.9 0.3 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CPSF100_C PF13299.1 CDO71405.1 - 2.4e-23 83.0 4.6 5.3e-23 81.9 0.0 3.0 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CDO71405.1 - 3e-12 46.5 0.0 9.7e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain ILVD_EDD PF00920.16 CDO71408.1 - 6.1e-201 668.3 0.0 7e-201 668.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Septin PF00735.13 CDO71409.1 - 9.6e-30 103.5 0.0 2.1e-09 36.8 0.0 3.1 3 0 0 3 3 3 3 Septin Zn_clus PF00172.13 CDO71409.1 - 1.9e-12 46.8 28.4 2.9e-08 33.4 7.9 2.9 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Septin PF00735.13 CDO71410.1 - 2.1e-49 168.0 0.2 6.5e-19 68.0 0.0 3.9 4 0 0 4 4 4 3 Septin GTP_EFTU PF00009.22 CDO71410.1 - 2.5e-06 27.0 0.0 1.7e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDO71410.1 - 0.00021 21.2 0.0 0.00049 20.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CDO71410.1 - 0.0024 17.7 0.2 0.91 9.3 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 CDO71410.1 - 0.0044 17.5 0.0 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 CDO71410.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CDO71410.1 - 0.034 14.2 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CDO71410.1 - 0.053 13.3 0.0 0.43 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CDO71410.1 - 0.072 11.7 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SRPRB PF09439.5 CDO71410.1 - 0.086 12.0 0.1 0.24 10.5 0.0 1.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 CDO71410.1 - 0.1 12.5 0.4 0.32 10.9 0.3 1.8 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CDO71410.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CDO71410.1 - 0.17 12.1 1.2 0.21 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain CM_2 PF01817.16 CDO71411.1 - 4.3e-13 49.1 0.1 2.1e-09 37.3 0.0 3.1 2 1 0 2 2 2 2 Chorismate mutase type II RPAP1_N PF08621.5 CDO71411.1 - 0.083 12.5 3.9 9.3 5.9 0.0 3.7 4 0 0 4 4 4 0 RPAP1-like, N-terminal Thi4 PF01946.12 CDO71412.1 - 3.8e-16 58.8 0.1 6.4e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NDK PF00334.14 CDO71413.1 - 1.4e-16 60.4 0.0 4.2e-16 58.9 0.0 1.7 1 1 0 1 1 1 1 Nucleoside diphosphate kinase Mmp37 PF09139.6 CDO71414.1 - 1.7e-103 346.1 0.0 2e-103 345.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Aldo_ket_red PF00248.16 CDO71415.1 - 9.5e-19 67.2 0.3 2.3e-10 39.7 0.1 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DUF2303 PF10065.4 CDO71415.1 - 0.14 10.9 1.9 1.2 7.9 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2303) Eaf7 PF07904.8 CDO71416.1 - 1.5e-13 50.5 0.0 2.3e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Alg6_Alg8 PF03155.10 CDO71417.1 - 2.5e-109 366.2 12.8 7e-102 341.6 4.1 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Ribosomal_L22 PF00237.14 CDO71417.1 - 2.6e-30 104.4 0.2 4.6e-30 103.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e GRASP55_65 PF04495.9 CDO71418.1 - 1.2e-09 38.3 0.0 1.6e-09 37.8 0.0 1.3 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 CDO71418.1 - 2e-05 24.3 0.0 4.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Acyl-CoA_dh_1 PF00441.19 CDO71419.1 - 5e-17 62.3 0.2 9.4e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CDO71419.1 - 4.9e-07 29.1 0.0 1.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CDO71419.1 - 0.00013 22.2 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CDO71419.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Cation_ATPase_C PF00689.16 CDO71420.1 - 0.093 12.2 9.7 0.32 10.4 6.8 1.9 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2663 PF10864.3 CDO71420.1 - 0.26 11.5 1.1 1.1 9.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) YfhO PF09586.5 CDO71420.1 - 0.3 9.0 2.2 0.42 8.5 1.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SdpI PF13630.1 CDO71420.1 - 1.4 8.7 9.6 0.51 10.0 0.3 2.9 2 0 0 2 2 2 0 SdpI/YhfL protein family 4HBT PF03061.17 CDO71421.1 - 3e-14 52.9 0.3 4.1e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 CDO71421.1 - 0.007 16.1 0.0 0.0075 16.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DER1 PF04511.10 CDO71422.1 - 1.1e-46 158.8 4.2 2e-46 158.0 2.9 1.4 1 0 0 1 1 1 1 Der1-like family SET PF00856.23 CDO71423.1 - 4e-09 36.9 0.2 6.7e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 SET domain Pro_isomerase PF00160.16 CDO71424.1 - 4.5e-49 166.6 0.0 7.7e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CDO71424.1 - 1.4e-11 43.7 0.1 0.00023 20.9 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-AN1 PF01428.11 CDO71425.1 - 2.8e-19 68.6 25.7 3.9e-10 39.4 5.0 2.6 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CDO71425.1 - 0.00023 21.3 15.1 0.0022 18.1 1.2 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain Spc7_N PF15402.1 CDO71425.1 - 7.3 4.4 10.4 8.9 4.1 7.2 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 His_Phos_1 PF00300.17 CDO71426.1 - 6.3e-21 75.1 0.0 8.8e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ufd2P_core PF10408.4 CDO71427.1 - 6.9e-196 652.2 0.2 8.3e-196 651.9 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CDO71427.1 - 3.3e-30 103.8 0.5 1.9e-29 101.4 0.4 2.4 2 0 0 2 2 2 1 U-box domain Mon1 PF03164.9 CDO71428.1 - 6.3e-44 150.2 0.0 2e-35 122.1 0.0 2.0 2 0 0 2 2 2 2 Trafficking protein Mon1 BTB PF00651.26 CDO71429.1 - 2.1e-05 24.4 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Amidohydro_1 PF01979.15 CDO71430.1 - 3.2e-17 63.2 0.0 3.7e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CDO71430.1 - 0.00019 20.8 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family A_deaminase PF00962.17 CDO71430.1 - 0.032 13.1 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Adenosine/AMP deaminase tRNA_int_endo_N PF02778.9 CDO71430.1 - 0.072 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain EBP PF05241.7 CDO71431.1 - 1.9e-63 212.9 10.8 2.5e-63 212.6 7.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein ORC6 PF05460.8 CDO71432.1 - 0.0012 18.0 0.1 0.0012 18.0 0.1 3.9 2 1 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) FAM220 PF15487.1 CDO71432.1 - 7.3 5.8 16.3 0.099 12.0 1.6 2.4 2 0 0 2 2 2 0 FAM220 family YjeF_N PF03853.10 CDO71433.1 - 9.3e-19 67.6 0.0 1.1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus zf-MYND PF01753.13 CDO71434.1 - 1.3e-10 41.0 5.9 6e-10 38.8 4.1 2.3 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 CDO71434.1 - 0.00018 21.3 1.0 0.00056 19.7 0.7 1.9 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 vATP-synt_AC39 PF01992.11 CDO71435.1 - 1.9e-46 158.7 0.0 2.1e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CRAL_TRIO PF00650.15 CDO71436.1 - 8e-28 96.9 0.0 1.1e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CDO71436.1 - 4.8e-09 36.2 0.2 1.1e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyco_hydro_71 PF03659.9 CDO71437.1 - 3.7e-84 282.4 0.2 4.4e-84 282.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_71 PF03659.9 CDO71438.1 - 1.2e-89 300.4 2.9 1.7e-89 300.0 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Ribosomal_L6 PF00347.18 CDO71439.1 - 4.1e-26 91.2 0.0 4.2e-15 56.0 0.0 2.4 3 0 0 3 3 3 2 Ribosomal protein L6 tRNA_bind PF01588.15 CDO71440.1 - 2.1e-29 101.1 0.0 4e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 CDO71440.1 - 0.00026 21.3 0.9 0.00054 20.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO71440.1 - 0.00065 19.6 0.0 0.00065 19.6 0.0 2.2 2 1 0 2 2 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO71440.1 - 0.014 15.2 0.1 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mitofilin PF09731.4 CDO71440.1 - 0.015 14.0 13.3 0.019 13.6 9.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2201_N PF13203.1 CDO71440.1 - 0.027 13.6 4.8 0.039 13.1 3.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain AF-4 PF05110.8 CDO71440.1 - 0.18 9.6 17.0 0.23 9.3 11.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDC27 PF09507.5 CDO71440.1 - 0.24 10.5 22.4 0.32 10.1 15.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.10 CDO71440.1 - 1.2 7.6 4.6 1.5 7.3 3.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NARP1 PF12569.3 CDO71440.1 - 1.2 7.7 20.6 2 7.0 14.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1764 PF08576.5 CDO71440.1 - 4.1 8.2 19.2 27 5.6 13.3 2.2 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF1510 PF07423.6 CDO71440.1 - 4.2 6.6 20.8 6.9 5.9 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 CDO71440.1 - 5.2 6.8 5.1 9.3 6.0 3.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DIOX_N PF14226.1 CDO71441.1 - 6.9e-24 84.6 0.0 9.9e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO71441.1 - 2.9e-07 30.7 0.0 6.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBFD_NFYB_HMF PF00808.18 CDO71442.1 - 6.9e-08 32.4 0.0 9.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HSP20 PF00011.16 CDO71443.1 - 2.8e-16 59.2 0.2 9.3e-10 38.2 0.0 2.1 1 1 0 2 2 2 2 Hsp20/alpha crystallin family Myosin_N PF02736.14 CDO71443.1 - 3 7.5 4.6 14 5.4 0.3 2.9 2 1 1 3 3 3 0 Myosin N-terminal SH3-like domain DUF1325 PF07039.6 CDO71444.1 - 1.7e-27 95.5 0.0 2.4e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain SEN1_N PF12726.2 CDO71445.1 - 5.5e-113 378.4 2.1 8.1e-113 377.9 1.4 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 CDO71445.1 - 3.2e-67 226.5 0.7 1.3e-66 224.5 0.5 2.1 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 CDO71445.1 - 7.2e-61 205.0 0.0 2.4e-60 203.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDO71445.1 - 2.3e-11 43.2 0.1 7.9e-11 41.5 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CDO71445.1 - 8.7e-08 31.9 0.0 9.2e-05 22.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CDO71445.1 - 1.8e-05 24.4 0.2 0.0089 15.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF3552 PF12072.3 CDO71445.1 - 0.002 17.3 8.5 0.0055 15.9 5.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) AAA_22 PF13401.1 CDO71445.1 - 0.014 15.5 1.1 0.29 11.2 0.2 3.1 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.1 CDO71445.1 - 0.024 14.0 0.0 0.077 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Glyco_hydro_71 PF03659.9 CDO71446.1 - 1.3e-95 320.1 3.1 1.7e-95 319.7 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 HMG-CoA_red PF00368.13 CDO71446.1 - 0.004 15.8 0.0 0.011 14.4 0.0 1.6 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A reductase CS PF04969.11 CDO71447.1 - 2.2e-09 37.7 0.0 5.5e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 CS domain SAD_SRA PF02182.12 CDO71448.1 - 7.6e-35 119.5 0.1 2e-34 118.1 0.1 1.6 1 1 0 1 1 1 1 SAD/SRA domain PP2C PF00481.16 CDO71449.1 - 1.4e-70 237.6 0.0 2.1e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CDO71449.1 - 0.0056 16.1 0.0 0.019 14.3 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Nop14 PF04147.7 CDO71449.1 - 0.74 7.6 4.4 1 7.1 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family Scm3 PF10384.4 CDO71451.1 - 3.5e-06 26.3 0.1 1.4e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Centromere protein Scm3 TMEM171 PF15471.1 CDO71451.1 - 9.4 4.9 6.6 14 4.3 4.5 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 zf-ribbon_3 PF13248.1 CDO71452.1 - 0.17 11.0 7.5 0.29 10.4 5.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain BUD22 PF09073.5 CDO71453.1 - 4.2e-26 92.0 21.6 1.8e-17 63.5 7.5 2.2 1 1 1 2 2 2 2 BUD22 F-box-like PF12937.2 CDO71455.1 - 3.3e-08 33.1 0.0 8.1e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 F-box-like APH PF01636.18 CDO71457.1 - 2.1e-14 53.8 0.4 4.3e-14 52.8 0.3 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO71457.1 - 7.5e-09 35.4 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 CDO71457.1 - 0.076 12.1 0.0 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.9 CDO71457.1 - 0.093 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDO71458.1 - 7e-05 22.6 0.2 0.00052 19.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO71458.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase ATP-synt_ab PF00006.20 CDO71459.1 - 5.6e-49 166.5 0.0 2.3e-46 158.0 0.0 2.2 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CDO71459.1 - 3.4e-17 62.9 0.1 7.4e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CDO71459.1 - 9.8e-12 44.9 0.9 2e-11 43.9 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CDO71459.1 - 0.002 17.9 0.3 0.0044 16.8 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain TFCD_C PF12612.3 CDO71460.1 - 1.3e-34 119.3 0.0 1.1e-33 116.3 0.0 2.4 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 CDO71460.1 - 0.012 15.8 12.9 0.069 13.4 0.9 5.3 3 2 3 6 6 6 0 HEAT repeats B56 PF01603.15 CDO71460.1 - 0.11 11.1 0.1 0.32 9.5 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) HEAT PF02985.17 CDO71460.1 - 0.31 11.2 8.1 20 5.5 0.4 6.3 7 0 0 7 7 7 0 HEAT repeat DDE_3 PF13358.1 CDO71461.1 - 0.037 13.7 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease PH_4 PF15404.1 CDO71462.1 - 7.5e-28 97.3 0.3 1.3e-24 86.7 0.1 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain DUF755 PF05501.6 CDO71462.1 - 8.2 6.5 8.2 20 5.2 5.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosom_S12_S23 PF00164.20 CDO71463.1 - 1.5e-35 121.2 0.3 2.1e-35 120.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 zf-Nse PF11789.3 CDO71464.1 - 3.6e-16 58.4 0.1 6.2e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CDO71464.1 - 0.0053 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 CDO71464.1 - 0.034 13.8 0.1 0.074 12.7 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF4404 PF14357.1 CDO71464.1 - 0.065 13.6 0.0 0.065 13.6 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) zf-C3HC4_2 PF13923.1 CDO71464.1 - 0.067 13.2 0.2 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO71464.1 - 0.081 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Ring finger domain DDE_1 PF03184.14 CDO71465.1 - 1.4e-48 164.8 0.0 2.2e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CDO71465.1 - 6.4e-11 41.9 0.1 1.9e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MRP-L47 PF06984.8 CDO71466.1 - 4.1e-20 71.4 1.0 9e-20 70.3 0.7 1.6 1 1 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) SQS_PSY PF00494.14 CDO71467.1 - 3.7e-42 144.4 0.0 4.5e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Amidohydro_5 PF13594.1 CDO71469.1 - 0.22 11.3 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Amidohydrolase DIOX_N PF14226.1 CDO71470.1 - 1.3e-23 83.6 0.0 2.1e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO71470.1 - 3.1e-14 53.0 0.0 5.9e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CDO71471.1 - 5.2e-23 81.7 0.0 8.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO71471.1 - 1e-19 70.6 0.0 1.5e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.2 CDO71472.1 - 1.2e-11 44.9 0.1 1.5e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO71472.1 - 0.043 13.5 0.1 0.049 13.3 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family AOX PF01786.12 CDO71473.1 - 2.4e-85 285.1 0.3 2.9e-85 284.8 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase Tropomodulin PF03250.9 CDO71473.1 - 0.045 13.2 0.1 0.093 12.2 0.1 1.5 1 0 0 1 1 1 0 Tropomodulin Fungal_trans PF04082.13 CDO71474.1 - 4.1e-10 38.9 0.1 7.2e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CDO71474.1 - 0.015 15.2 16.0 0.028 14.3 11.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridox_oxidase PF01243.15 CDO71475.1 - 8.3e-23 80.2 0.2 1.3e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 CDO71475.1 - 2.7e-13 49.1 0.3 5.3e-13 48.2 0.2 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 CDO71475.1 - 4.1e-06 27.0 0.1 6.7e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Kelch_6 PF13964.1 CDO71476.1 - 1.4e-20 72.5 2.2 0.00011 22.1 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 CDO71476.1 - 8.1e-20 70.3 0.5 0.00013 21.6 0.0 4.8 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CDO71476.1 - 2.4e-17 62.5 2.8 1.3e-06 28.3 0.0 7.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CDO71476.1 - 1.8e-16 59.7 1.2 4.8e-05 23.2 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 CDO71476.1 - 6e-16 57.7 0.0 0.00018 20.9 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CDO71476.1 - 1.7e-14 52.9 0.1 0.0061 16.2 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Lustrin_cystein PF14625.1 CDO71477.1 - 0.85 9.7 5.3 2.9 8.0 0.5 2.3 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Lipase_3 PF01764.20 CDO71479.1 - 1.1e-24 86.6 0.0 1.6e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) FHA PF00498.21 CDO71479.1 - 8.1e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain Abhydrolase_6 PF12697.2 CDO71479.1 - 0.00026 20.9 0.1 0.00072 19.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CDO71479.1 - 0.0073 15.9 0.1 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 CDO71479.1 - 0.009 15.5 0.9 0.018 14.5 0.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO71479.1 - 0.031 14.0 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 CDO71479.1 - 0.082 12.6 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) zf-C2H2 PF00096.21 CDO71480.1 - 0.00023 21.3 5.6 0.27 11.6 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO71480.1 - 0.00051 20.1 3.5 0.19 12.1 1.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CDO71480.1 - 0.082 13.2 3.0 0.78 10.1 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.20 CDO71481.1 - 3e-66 223.2 0.0 3.7e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71481.1 - 6.9e-36 123.6 0.0 4.8e-35 120.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO71481.1 - 1.6e-05 24.0 0.0 4.4e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CDO71481.1 - 0.067 12.0 0.1 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 CDO71481.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M3 PF01432.15 CDO71482.1 - 3.9e-133 444.8 0.0 5.4e-133 444.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 CDO71482.1 - 0.017 14.4 0.2 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like RIO1 PF01163.17 CDO71483.1 - 1.8e-37 128.5 4.3 1.4e-23 83.2 0.0 2.8 3 0 0 3 3 3 2 RIO1 family Peptidase_M3 PF01432.15 CDO71484.1 - 2.7e-105 353.0 0.5 4.9e-63 213.7 0.2 2.1 1 1 1 2 2 2 2 Peptidase family M3 Peptidase_M50B PF13398.1 CDO71484.1 - 0.19 11.0 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase M50B-like UDPGT PF00201.13 CDO71485.1 - 1.6e-17 63.2 0.1 4.3e-17 61.8 0.1 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CDO71485.1 - 0.00081 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Usp PF00582.21 CDO71486.1 - 4e-05 23.8 0.1 0.00017 21.8 0.0 2.1 1 0 0 1 1 1 1 Universal stress protein family Pet127 PF08634.5 CDO71487.1 - 3.9e-90 301.7 0.4 5e-90 301.3 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Proteasom_Rpn13 PF04683.8 CDO71488.1 - 1.9e-28 98.3 0.0 2.7e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor LRR_4 PF12799.2 CDO71489.1 - 0.015 14.9 0.1 1.2 8.8 0.0 3.4 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) DUF2205 PF10224.4 CDO71490.1 - 6.3e-11 41.6 0.5 7.6e-11 41.4 0.3 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 CDO71490.1 - 0.0024 18.1 1.0 0.0027 18.0 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Borrelia_REV PF03978.8 CDO71490.1 - 0.053 13.2 1.0 0.064 12.9 0.7 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein AAA_23 PF13476.1 CDO71491.1 - 1.7e-17 64.4 24.2 1.7e-17 64.4 16.8 8.8 1 1 2 3 3 1 1 AAA domain SMC_N PF02463.14 CDO71491.1 - 9.5e-17 60.9 15.0 7.6e-09 35.1 0.0 3.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDO71491.1 - 4.1e-15 56.5 1.5 5.5e-08 33.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 CDO71491.1 - 4.8e-11 42.4 0.0 2e-10 40.4 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CDO71491.1 - 4.6e-08 32.5 23.5 2.3e-07 30.2 0.0 3.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.1 CDO71491.1 - 2.5e-07 29.5 125.9 1.6e-05 23.6 0.0 8.3 3 1 3 8 8 8 4 AAA domain Reo_sigmaC PF04582.7 CDO71491.1 - 0.00058 19.1 40.8 0.0058 15.8 2.6 6.9 4 2 5 9 9 9 4 Reovirus sigma C capsid protein AAA_29 PF13555.1 CDO71491.1 - 0.0007 19.0 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 CDO71491.1 - 0.0045 16.2 34.0 0.0045 16.2 23.6 8.1 3 3 4 8 8 8 2 Growth-arrest specific micro-tubule binding ABC_tran PF00005.22 CDO71491.1 - 0.0057 16.9 0.0 0.0057 16.9 0.0 7.3 5 2 2 7 7 5 2 ABC transporter Rad50_zn_hook PF04423.9 CDO71491.1 - 0.026 14.0 0.5 0.026 14.0 0.3 5.0 6 0 0 6 6 5 0 Rad50 zinc hook motif AAA_19 PF13245.1 CDO71491.1 - 0.053 13.2 0.4 0.31 10.8 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AMP-binding PF00501.23 CDO71492.1 - 2.4e-86 289.7 0.3 3.4e-86 289.2 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Cytochrom_B561 PF03188.11 CDO71492.1 - 0.0052 16.6 5.6 0.013 15.3 3.9 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4396 PF14342.1 CDO71492.1 - 0.025 14.6 0.8 0.025 14.6 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Diacid_rec PF05651.8 CDO71492.1 - 0.061 12.7 0.0 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 Putative sugar diacid recognition Pkinase PF00069.20 CDO71494.1 - 1.7e-52 178.1 0.0 2.6e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71494.1 - 4.6e-25 88.1 0.2 5.2e-23 81.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CDO71494.1 - 3.2e-06 26.3 0.4 8.9e-05 21.5 0.0 2.7 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.17 CDO71494.1 - 0.0014 17.9 0.1 0.0045 16.3 0.1 1.8 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CDO71494.1 - 0.004 16.2 0.1 0.0069 15.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family cobW PF02492.14 CDO71495.1 - 7.5e-21 74.3 0.0 1.9e-20 73.0 0.0 1.5 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 CDO71495.1 - 0.00075 19.4 0.0 0.0015 18.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase TIP49 PF06068.8 CDO71495.1 - 0.018 13.7 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_17 PF13207.1 CDO71495.1 - 0.025 15.4 0.1 0.048 14.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CDO71495.1 - 0.026 14.8 0.0 0.036 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CDO71495.1 - 0.033 14.4 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 CDO71495.1 - 0.048 12.5 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.18 CDO71495.1 - 0.05 13.0 0.2 0.084 12.2 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.9 CDO71495.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CDO71495.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 CDO71495.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Pox_A32 PF04665.7 CDO71495.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_16 PF13191.1 CDO71495.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain UPF0079 PF02367.12 CDO71495.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 CDO71495.1 - 0.14 10.9 0.0 1.9 7.2 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_25 PF13481.1 CDO71495.1 - 0.16 11.3 0.2 0.44 9.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 CDO71495.1 - 0.18 10.7 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Abhydrolase_6 PF12697.2 CDO71496.1 - 4.5e-29 101.9 0.0 5.8e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO71496.1 - 3.8e-14 52.7 0.0 9.5e-12 44.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO71496.1 - 8.5e-10 38.5 0.0 1.8e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO71496.1 - 1.9e-05 24.4 0.0 7.5e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 CDO71496.1 - 0.091 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme OB_NTP_bind PF07717.11 CDO71497.1 - 1.3e-29 102.3 0.1 3.9e-29 100.7 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CDO71497.1 - 2.8e-26 91.4 5.0 9.4e-26 89.8 0.0 3.6 4 0 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CDO71497.1 - 5e-14 51.9 0.0 1.5e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO71497.1 - 7.9e-07 28.7 0.1 5.4e-06 26.0 0.0 2.4 2 1 1 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CDO71497.1 - 8.4e-05 22.7 0.1 0.00057 20.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CDO71497.1 - 0.005 15.7 0.0 0.012 14.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 CDO71497.1 - 0.012 15.4 0.0 1.3 8.8 0.0 2.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF4243 PF14027.1 CDO71498.1 - 1.4e-64 218.6 0.0 7.5e-64 216.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4243) Pkinase PF00069.20 CDO71503.1 - 0.0064 15.6 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 CDO71504.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 CDO71505.1 - 8.1e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CDO71505.1 - 0.0026 17.5 1.0 0.12 12.0 0.3 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.15 CDO71505.1 - 0.0078 15.3 0.0 0.033 13.3 0.0 2.0 2 0 0 2 2 2 1 Ecdysteroid kinase Kdo PF06293.9 CDO71505.1 - 0.0088 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pam16 PF03656.8 CDO71505.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Pam16 Peptidase_M20 PF01546.23 CDO71506.1 - 7e-30 103.9 0.0 1.2e-29 103.1 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CDO71506.1 - 4.7e-13 48.8 0.0 7.5e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain p450 PF00067.17 CDO71507.1 - 3.9e-66 223.4 0.0 7.1e-66 222.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 UDPG_MGDP_dh_N PF03721.9 CDO71509.1 - 3e-48 163.6 0.0 5.3e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 CDO71509.1 - 3.8e-32 110.3 0.0 7e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 CDO71509.1 - 2e-27 95.4 0.1 8.6e-26 90.1 0.1 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Fibrillarin_2 PF10113.4 CDO71509.1 - 0.086 11.1 0.5 0.14 10.4 0.1 1.5 2 0 0 2 2 2 0 Fibrillarin-like archaeal protein NAD_binding_7 PF13241.1 CDO71509.1 - 0.094 12.9 0.3 0.61 10.3 0.1 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding UCH PF00443.24 CDO71510.1 - 2.8e-10 39.7 0.2 1.5e-09 37.3 0.7 1.7 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 CDO71510.1 - 0.0072 16.1 0.1 0.017 14.9 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 CDO71510.1 - 0.022 14.2 0.0 0.19 11.2 0.0 2.6 2 0 0 2 2 2 0 CUE domain DUF1664 PF07889.7 CDO71510.1 - 0.44 10.3 2.6 0.59 9.9 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) UIM PF02809.15 CDO71510.1 - 1.3 8.8 10.9 0.17 11.5 1.4 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif V_ATPase_I PF01496.14 CDO71510.1 - 1.9 6.2 4.0 2.7 5.7 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Aminotran_1_2 PF00155.16 CDO71511.1 - 1e-55 189.1 0.0 4.9e-45 154.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.15 CDO71511.1 - 0.00015 20.4 0.0 0.00028 19.5 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 CDO71511.1 - 0.00039 19.6 0.0 0.00075 18.7 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CDO71511.1 - 0.012 14.3 0.0 0.029 13.1 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Disulph_isomer PF06491.6 CDO71511.1 - 0.75 9.6 3.8 0.83 9.5 0.1 2.5 3 0 0 3 3 3 0 Disulphide isomerase Dus PF01207.12 CDO71512.1 - 8.7e-46 156.1 0.0 1.4e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 CDO71512.1 - 4.6e-06 26.1 4.7 0.0021 17.7 0.4 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) p450 PF00067.17 CDO71513.1 - 3.4e-66 223.6 0.0 9.6e-66 222.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 CDO71514.1 - 4.4e-47 160.8 6.6 7.8e-47 160.0 4.6 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO71514.1 - 3.4e-05 23.8 7.2 0.00077 19.4 3.8 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO71514.1 - 0.00096 19.6 7.6 0.13 12.7 1.8 3.0 3 0 0 3 3 3 2 Aspartyl protease C2 PF00168.25 CDO71515.1 - 3.9e-23 81.1 0.0 9.2e-13 47.8 0.0 2.7 2 0 0 2 2 2 2 C2 domain RNA_pol_Rpc34 PF05158.7 CDO71516.1 - 7.4e-75 252.1 0.4 1.5e-52 178.8 0.0 3.5 2 1 0 3 3 3 3 RNA polymerase Rpc34 subunit MIP-T3 PF10243.4 CDO71516.1 - 0.78 8.1 71.9 1.2 7.4 49.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 CDO71516.1 - 1.1 7.5 40.2 1.9 6.6 27.9 1.4 1 0 0 1 1 1 0 Transmembrane protein DUF936 PF06075.7 CDO71516.1 - 1.5 7.6 40.4 2.2 7.0 28.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) EST1 PF10374.4 CDO71517.1 - 6e-11 42.4 0.0 1.3e-09 38.0 0.0 2.6 2 1 0 2 2 2 1 Telomerase activating protein Est1 Activator_LAG-3 PF11498.3 CDO71517.1 - 0.2 10.3 7.9 0.3 9.7 5.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EST1_DNA_bind PF10373.4 CDO71518.1 - 7.4e-35 120.5 0.0 1.3e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain TPR_11 PF13414.1 CDO71518.1 - 0.082 12.5 0.2 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 TPR repeat SNF2_N PF00176.18 CDO71519.1 - 4.8e-76 255.4 0.0 8.8e-76 254.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDO71519.1 - 8.4e-15 54.4 0.0 3.5e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO71519.1 - 4.1e-06 26.7 0.0 2e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CDO71519.1 - 5.4e-05 22.7 0.0 0.005 16.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CDO71519.1 - 0.025 13.3 0.4 2.4 6.8 0.0 2.5 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Chorion_2 PF03964.10 CDO71519.1 - 0.07 13.6 0.1 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Chorion family 2 Fungal_trans PF04082.13 CDO71521.1 - 4.4e-16 58.5 0.1 1e-15 57.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain CitG PF01874.11 CDO71522.1 - 0.063 12.4 0.1 0.063 12.4 0.1 1.1 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Transposase_21 PF02992.9 CDO71523.1 - 2.6e-15 56.1 0.1 2e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 HTH_21 PF13276.1 CDO71525.1 - 0.24 11.4 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 HTH-like domain zf-RING_2 PF13639.1 CDO71527.1 - 5.8e-07 29.2 5.9 3e-05 23.7 0.6 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 CDO71527.1 - 2e-06 27.7 0.7 0.00051 20.0 0.2 2.4 2 0 0 2 2 2 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDO71527.1 - 0.00037 20.0 3.9 0.013 15.1 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO71527.1 - 0.012 15.2 7.7 0.016 14.8 1.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO71527.1 - 0.061 13.3 9.9 0.068 13.2 1.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-BED PF02892.10 CDO71527.1 - 0.18 11.6 3.1 3.2 7.6 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger zf-RING_5 PF14634.1 CDO71527.1 - 0.34 10.6 4.5 0.26 11.0 0.3 2.2 2 0 0 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 CDO71527.1 - 2.6 8.0 8.0 11 6.0 2.3 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain DUF1218 PF06749.7 CDO71528.1 - 0.014 15.8 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) DUF3357 PF11837.3 CDO71528.1 - 0.1 12.4 1.5 0.34 10.7 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) NicO PF03824.11 CDO71528.1 - 0.11 11.8 1.0 0.21 10.8 0.7 1.3 1 1 0 1 1 1 0 High-affinity nickel-transport protein Herpes_gE PF02480.11 CDO71528.1 - 4.6 5.3 4.8 12 3.9 0.4 2.5 1 1 2 3 3 3 0 Alphaherpesvirus glycoprotein E DUF4322 PF14210.1 CDO71529.1 - 0.091 12.2 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) Peptidase_S64 PF08192.6 CDO71530.1 - 0.0031 15.9 0.1 0.0047 15.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family S64 D123 PF07065.9 CDO71530.1 - 0.0075 15.3 2.6 0.026 13.5 0.0 2.3 3 0 0 3 3 3 1 D123 Nucleoplasmin PF03066.10 CDO71530.1 - 0.031 13.7 7.1 0.054 13.0 4.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CDO71530.1 - 0.098 12.9 10.6 0.25 11.5 7.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 CDO71530.1 - 0.26 10.8 5.3 0.55 9.8 3.7 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 CDO71530.1 - 0.7 7.7 5.5 1 7.1 3.8 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 CDO71530.1 - 1.3 7.9 3.7 2.5 7.0 2.6 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 CDO71530.1 - 1.4 6.8 4.2 2.1 6.3 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 CDO71530.1 - 1.6 8.5 6.5 3 7.6 4.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Daxx PF03344.10 CDO71530.1 - 8.9 4.6 8.5 13 4.1 5.9 1.1 1 0 0 1 1 1 0 Daxx Family INCENP_ARK-bind PF03941.10 CDO71531.1 - 4e-18 65.0 0.4 1.5e-17 63.2 0.3 2.1 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Sigma70_r1_2 PF00140.15 CDO71531.1 - 0.058 13.0 0.3 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 SNARE PF05739.14 CDO71532.1 - 3.6e-07 29.7 1.0 3.6e-07 29.7 0.7 3.7 4 1 1 5 5 5 1 SNARE domain V-SNARE_C PF12352.3 CDO71532.1 - 0.00094 19.2 3.3 0.28 11.2 0.2 2.8 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Sec34 PF04136.10 CDO71532.1 - 0.14 11.8 4.4 3 7.5 0.7 2.2 2 0 0 2 2 2 0 Sec34-like family Ribosomal_S30AE PF02482.14 CDO71532.1 - 3.8 8.0 8.7 0.43 11.0 0.3 2.6 3 0 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein Mpp10 PF04006.7 CDO71533.1 - 6.6e-99 331.9 80.3 1.1e-81 275.0 23.5 2.3 1 1 1 2 2 2 2 Mpp10 protein Amidase PF01425.16 CDO71533.1 - 4.4e-98 329.0 0.0 1.6e-97 327.1 0.0 1.8 2 0 0 2 2 2 1 Amidase FA_desaturase PF00487.19 CDO71534.1 - 6.7 6.0 7.4 1.6 8.1 0.7 2.1 2 0 0 2 2 2 0 Fatty acid desaturase Lyase_8 PF02278.13 CDO71535.1 - 1.3e-32 113.3 0.3 2.7e-32 112.2 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 CDO71535.1 - 3.6e-24 85.2 0.0 5.6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.12 CDO71535.1 - 0.0083 16.1 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Lyase_8 PF02278.13 CDO71536.1 - 5.8e-31 107.8 0.3 9.3e-31 107.1 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 CDO71536.1 - 1.3e-22 80.1 0.1 2e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.12 CDO71536.1 - 0.0021 18.0 0.1 0.0076 16.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Ribosomal_S3_C PF00189.15 CDO71537.1 - 5.1e-16 58.6 0.1 9.6e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CDO71537.1 - 3.7e-12 45.6 0.0 6.6e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 CDO71537.1 - 0.045 14.0 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Thiolase_C PF02803.13 CDO71538.1 - 1.7e-41 140.5 0.1 3.4e-41 139.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 CDO71538.1 - 6.7e-23 81.0 0.3 1.2e-18 67.0 0.1 2.5 1 1 0 2 2 2 2 Thiolase, N-terminal domain Ldh_1_C PF02866.13 CDO71538.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain CBM-like PF14683.1 CDO71539.1 - 1.9e-11 43.9 0.1 3.2e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 CDO71539.1 - 5.5e-06 26.4 1.6 6.7e-06 26.1 0.1 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 CDO71539.1 - 0.0077 16.2 0.3 0.0077 16.2 0.2 1.9 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain SAD_SRA PF02182.12 CDO71540.1 - 6.5e-44 148.9 0.0 1.1e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain MAD PF05557.8 CDO71541.1 - 0.0071 14.4 0.1 0.0098 14.0 0.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein INO80_Ies4 PF08193.6 CDO71541.1 - 0.017 15.0 3.2 0.028 14.3 2.2 1.3 1 0 0 1 1 1 0 INO80 complex subunit Ies4 zf-CCCH PF00642.19 CDO71541.1 - 0.024 14.3 3.5 0.024 14.3 2.4 3.8 4 1 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CENP-F_leu_zip PF10473.4 CDO71541.1 - 0.093 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cast PF10174.4 CDO71541.1 - 0.21 9.5 0.0 0.28 9.1 0.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Mucin PF01456.12 CDO71543.1 - 0.48 10.1 7.4 0.6 9.8 5.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein PT PF04886.7 CDO71543.1 - 6.4 6.1 11.6 2.6 7.4 4.1 2.3 2 1 0 2 2 2 0 PT repeat UPF0160 PF03690.8 CDO71544.1 - 2e-128 428.2 0.0 2.6e-128 427.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SurE PF01975.12 CDO71544.1 - 4.3e-20 71.8 0.0 9.1e-19 67.5 0.0 2.2 1 1 0 1 1 1 1 Survival protein SurE Glyco_hydro_16 PF00722.16 CDO71545.1 - 7.1e-08 31.9 0.0 2.5e-07 30.1 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Thioredoxin_5 PF13743.1 CDO71545.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Ribosomal_L15e PF00827.12 CDO71546.1 - 2.3e-92 307.8 12.8 2.6e-92 307.6 8.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 RVT_1 PF00078.22 CDO71547.1 - 2.1e-38 131.8 0.0 3.7e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CDO71547.1 - 9.3e-16 58.5 0.1 1.7e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF445 PF04286.7 CDO71547.1 - 0.077 12.5 4.0 1.3 8.4 1.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF445) FlxA PF14282.1 CDO71547.1 - 0.57 10.1 3.3 1.4 8.8 2.3 1.7 1 0 0 1 1 1 0 FlxA-like protein MFS_1 PF07690.11 CDO71549.1 - 5.6e-08 31.8 20.8 4.8e-07 28.8 5.4 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily BioY PF02632.9 CDO71549.1 - 0.042 13.4 5.8 7.6 6.1 0.0 4.1 4 1 0 4 4 4 0 BioY family PsaM PF07465.8 CDO71549.1 - 0.086 12.4 0.4 0.49 10.0 0.0 2.4 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Miro PF08477.8 CDO71550.1 - 0.00071 20.0 0.0 0.0053 17.2 0.0 2.3 2 1 0 2 2 2 1 Miro-like protein Rad17 PF03215.10 CDO71550.1 - 0.008 14.9 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CDO71550.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 CDO71550.1 - 0.035 13.4 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Ras family AAA_17 PF13207.1 CDO71550.1 - 0.047 14.4 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CDO71550.1 - 0.073 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CDO71550.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 CDO71550.1 - 0.14 11.9 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CDO71550.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 CDO71550.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RasGEF PF00617.14 CDO71551.1 - 8.9e-28 97.2 0.0 1.6e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain DEAD PF00270.24 CDO71552.1 - 1.6e-46 157.8 0.0 3.7e-45 153.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO71552.1 - 1.3e-24 85.8 0.0 3.6e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CDO71552.1 - 0.013 13.9 0.2 0.2 10.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 CDO71552.1 - 0.076 13.1 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Apc4 PF12896.2 CDO71553.1 - 5.9e-33 113.9 0.3 1e-32 113.1 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 CDO71553.1 - 0.099 12.1 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C2HC5 PF06221.8 CDO71555.1 - 0.094 12.4 0.6 0.14 11.8 0.4 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Actin PF00022.14 CDO71556.1 - 5.4e-136 453.1 0.0 6.1e-136 452.9 0.0 1.0 1 0 0 1 1 1 1 Actin Ribosomal_S24e PF01282.14 CDO71557.1 - 3.5e-33 113.2 0.0 5.6e-33 112.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Tic20 PF09685.5 CDO71558.1 - 1.6e-06 28.0 3.0 2.2e-06 27.5 2.1 1.1 1 0 0 1 1 1 1 Tic20-like protein HEAT PF02985.17 CDO71561.1 - 1.2e-43 143.2 20.3 0.0011 18.8 0.0 12.5 13 0 0 13 13 13 9 HEAT repeat HEAT_2 PF13646.1 CDO71561.1 - 2.4e-35 120.6 12.3 4e-10 39.8 0.0 6.8 3 2 3 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 CDO71561.1 - 4.2e-14 52.7 1.4 3.4e-05 24.1 0.0 6.7 2 1 7 9 9 9 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 CDO71561.1 - 4.2e-11 41.8 1.9 4.6e-07 28.5 0.3 3.9 2 1 1 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.1 CDO71561.1 - 4.9e-10 39.6 15.6 0.18 12.3 0.0 8.9 7 2 3 10 10 10 2 HEAT-like repeat Cnd1 PF12717.2 CDO71561.1 - 4.2e-06 26.7 3.6 0.0033 17.2 0.1 5.0 3 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CDO71561.1 - 9.2e-06 25.2 5.8 1.3 8.9 0.0 6.5 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 CDO71561.1 - 5.1e-05 22.7 1.6 0.27 10.5 0.1 4.7 2 1 2 5 5 5 1 CLASP N terminal DUF1546 PF07571.8 CDO71561.1 - 0.00016 21.7 0.1 0.16 12.0 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1546) Ipi1_N PF12333.3 CDO71561.1 - 0.0012 18.8 0.0 0.0099 15.8 0.0 2.6 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Ecm29 PF13001.2 CDO71561.1 - 0.019 13.4 2.2 4.6 5.5 0.0 3.5 4 1 1 5 5 5 0 Proteasome stabiliser DUF3323 PF11796.3 CDO71561.1 - 0.02 14.1 0.2 0.02 14.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Proteasom_PSMB PF10508.4 CDO71561.1 - 0.023 12.9 6.3 0.029 12.6 0.4 3.0 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 CDO71561.1 - 0.037 14.4 5.1 9 7.0 0.2 5.6 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat DUF682 PF05081.7 CDO71561.1 - 0.093 12.2 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF682) Aldose_epim PF01263.15 CDO71562.1 - 6.3e-29 101.0 0.6 7.6e-29 100.7 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DNA_pol_B PF00136.16 CDO71563.1 - 7.3e-94 315.1 0.0 1e-93 314.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CDO71563.1 - 1.8e-19 69.7 0.0 5.8e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CDO71563.1 - 4.7e-14 52.1 5.5 9.6e-14 51.1 3.8 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 CDO71563.1 - 0.38 9.3 0.5 0.61 8.6 0.4 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral AGTRAP PF06396.6 CDO71564.1 - 0.00048 19.8 3.2 0.0015 18.2 2.2 1.8 1 1 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Peptidase_A22B PF04258.8 CDO71564.1 - 0.039 13.4 1.4 0.069 12.5 1.0 1.3 1 1 0 1 1 1 0 Signal peptide peptidase Glyco_transf_41 PF13844.1 CDO71565.1 - 3.1e-66 223.2 1.1 2.9e-36 124.4 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 CDO71565.1 - 9.3e-14 50.8 0.1 0.00082 18.9 0.0 5.8 3 2 2 5 5 5 4 TPR repeat TPR_17 PF13431.1 CDO71565.1 - 3.5e-10 39.2 2.1 0.15 12.2 0.0 6.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDO71565.1 - 1.2e-09 37.4 0.2 0.018 14.6 0.0 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDO71565.1 - 9e-08 31.9 3.1 0.00036 20.3 0.1 5.1 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 CDO71565.1 - 1.8e-06 27.4 0.4 0.51 10.3 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO71565.1 - 2e-06 27.1 2.2 0.0019 17.8 0.0 4.2 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDO71565.1 - 4.1e-05 24.1 1.4 0.43 11.3 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO71565.1 - 0.0002 21.7 0.2 6.3 7.7 0.0 5.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 CDO71565.1 - 0.03 14.2 8.8 4.1 7.4 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 CDO71565.1 - 0.18 12.1 2.2 9.2 6.6 0.0 3.6 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDO71565.1 - 0.54 10.1 5.5 0.78 9.6 0.0 4.0 6 0 0 6 6 5 0 Tetratricopeptide repeat WAC_Acf1_DNA_bd PF10537.4 CDO71566.1 - 0.098 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal Transaldolase PF00923.14 CDO71567.1 - 2.3e-32 112.2 0.0 1.7e-31 109.4 0.0 2.0 1 1 0 1 1 1 1 Transaldolase Med20 PF08612.6 CDO71568.1 - 0.00077 18.6 0.0 0.00077 18.6 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex WD40 PF00400.27 CDO71569.1 - 4.1e-11 42.3 10.4 0.002 17.9 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Pex24p PF06398.6 CDO71571.1 - 2.2e-09 36.5 1.1 2.8e-09 36.2 0.8 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HA2 PF04408.18 CDO71572.1 - 7.5e-20 70.8 0.1 2.3e-19 69.2 0.1 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) dsrm PF00035.20 CDO71572.1 - 3.4e-12 46.7 0.0 0.00018 22.0 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.26 CDO71572.1 - 1.8e-11 43.7 0.1 4.1e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO71572.1 - 1.3e-07 31.3 0.1 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 CDO71572.1 - 4.2e-07 29.8 0.0 9.2e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CDO71572.1 - 0.004 17.2 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CDO71572.1 - 0.04 13.7 0.1 0.96 9.2 0.1 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Adaptin_N PF01602.15 CDO71573.1 - 1.1e-126 423.3 5.5 1.5e-126 422.8 3.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 CDO71573.1 - 3.1e-38 130.2 0.0 9.1e-38 128.7 0.0 1.8 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 CDO71573.1 - 7.3e-15 55.2 0.0 1.6e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CDO71573.1 - 0.012 15.8 4.1 2.2 8.6 0.1 3.7 2 2 3 5 5 5 0 HEAT repeats HEAT PF02985.17 CDO71573.1 - 0.093 12.8 2.1 11 6.4 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat Flavodoxin_3 PF12641.2 CDO71573.1 - 0.16 11.3 0.1 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain RasGAP PF00616.14 CDO71574.1 - 6.7e-36 123.8 0.0 9.9e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 CDO71574.1 - 3.9e-10 39.4 0.0 7.2e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain ELO PF01151.13 CDO71575.1 - 1.4e-60 204.7 20.2 1.6e-60 204.5 14.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Bac_export_2 PF01312.14 CDO71575.1 - 1.2 8.0 3.7 1.5 7.6 2.5 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Atg14 PF10186.4 CDO71576.1 - 0.066 12.1 5.0 0.13 11.1 3.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1162 PF06650.7 CDO71578.1 - 1.2e-62 211.6 0.0 4.9e-60 203.0 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CDO71578.1 - 5.4e-32 109.8 0.1 1.6e-31 108.2 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 CDO71578.1 - 1e-06 28.8 0.0 2.9e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain Gag_p24 PF00607.15 CDO71578.1 - 0.032 13.7 0.1 0.087 12.3 0.1 1.7 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) DENN PF02141.16 CDO71579.1 - 3.4e-18 66.0 0.0 8.3e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain Tup_N PF08581.5 CDO71579.1 - 0.61 10.3 12.8 0.3 11.3 6.5 2.2 1 1 0 1 1 1 0 Tup N-terminal DUF972 PF06156.8 CDO71579.1 - 0.73 10.2 14.7 6 7.2 1.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMCO5 PF14992.1 CDO71579.1 - 1.1 8.3 17.1 0.034 13.3 7.0 1.9 2 0 0 2 2 2 0 TMCO5 family AAA_13 PF13166.1 CDO71579.1 - 1.6 7.0 9.8 0.13 10.6 2.5 1.9 2 0 0 2 2 2 0 AAA domain Filament PF00038.16 CDO71579.1 - 3.3 7.0 22.6 0.04 13.4 9.6 2.0 2 0 0 2 2 2 0 Intermediate filament protein Mg_trans_NIPA PF05653.9 CDO71580.1 - 6e-14 51.7 13.7 2.3e-10 39.9 3.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA MMR1 PF08505.5 CDO71580.1 - 1.7 8.6 7.3 0.29 11.1 0.9 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein AAA_2 PF07724.9 CDO71582.1 - 5.7e-51 172.8 0.0 1.9e-47 161.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CDO71582.1 - 5.3e-26 90.3 2.6 6.8e-26 89.9 0.4 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CDO71582.1 - 7.7e-24 84.3 0.0 7.2e-13 48.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.15 CDO71582.1 - 2.3e-14 53.0 4.2 4.8e-10 39.2 0.0 4.4 3 1 0 3 3 3 2 Clp amino terminal domain AAA_5 PF07728.9 CDO71582.1 - 2.5e-14 53.1 0.0 6.1e-07 29.2 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDO71582.1 - 2.5e-12 47.1 3.4 0.00012 22.0 0.0 5.5 3 2 3 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 CDO71582.1 - 9e-11 42.0 0.1 0.0018 18.4 0.0 4.3 3 2 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 CDO71582.1 - 5.5e-08 32.4 0.0 9.5e-05 21.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 CDO71582.1 - 9.8e-07 28.3 0.0 0.0014 18.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 CDO71582.1 - 3.3e-05 24.1 2.3 0.017 15.3 0.0 3.3 4 0 0 4 4 2 1 AAA domain Mg_chelatase PF01078.16 CDO71582.1 - 3.4e-05 23.1 0.0 0.029 13.5 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CDO71582.1 - 5.3e-05 22.1 1.7 0.28 9.8 0.0 3.4 3 1 1 4 4 4 2 TIP49 C-terminus RNA_helicase PF00910.17 CDO71582.1 - 8e-05 22.7 0.0 0.84 9.8 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_17 PF13207.1 CDO71582.1 - 0.00027 21.7 9.6 0.13 13.0 2.4 4.0 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CDO71582.1 - 0.001 18.7 0.2 0.81 9.4 0.0 3.3 3 0 0 3 3 2 1 Part of AAA domain Zeta_toxin PF06414.7 CDO71582.1 - 0.0011 18.1 0.1 0.12 11.4 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 CDO71582.1 - 0.0017 18.2 0.0 0.76 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CDO71582.1 - 0.0017 18.7 1.7 3.6 7.8 0.4 3.4 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CDO71582.1 - 0.0026 17.5 0.3 1 8.9 0.0 3.6 3 1 0 4 4 4 1 Archaeal ATPase AAA_24 PF13479.1 CDO71582.1 - 0.0032 17.0 0.0 0.099 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CDO71582.1 - 0.0076 15.7 0.0 3.6 7.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Torsin PF06309.6 CDO71582.1 - 0.018 14.9 0.0 0.38 10.6 0.0 2.5 3 0 0 3 3 2 0 Torsin AAA_28 PF13521.1 CDO71582.1 - 0.021 14.7 0.4 5.3 6.9 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 CDO71582.1 - 0.026 13.9 2.4 10 5.4 0.0 3.7 3 1 0 4 4 4 0 AAA domain NACHT PF05729.7 CDO71582.1 - 0.04 13.5 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 CDO71582.1 - 0.052 12.7 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ResIII PF04851.10 CDO71582.1 - 0.061 13.1 0.0 0.59 9.9 0.0 2.5 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CDO71582.1 - 0.064 12.4 0.1 2.2 7.4 0.0 2.6 3 0 0 3 3 2 0 PhoH-like protein ABC_tran PF00005.22 CDO71582.1 - 0.08 13.2 0.1 17 5.7 0.0 2.9 3 0 0 3 3 2 0 ABC transporter MobB PF03205.9 CDO71582.1 - 0.088 12.5 0.0 14 5.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_S46 PF10459.4 CDO71582.1 - 0.9 7.8 5.2 1.5 7.1 3.6 1.3 1 0 0 1 1 1 0 Peptidase S46 KaiC PF06745.8 CDO71582.1 - 0.94 8.5 3.6 5.7 5.9 0.0 3.7 4 1 1 5 5 5 0 KaiC IncA PF04156.9 CDO71582.1 - 4.6 6.7 7.5 12 5.4 5.2 1.7 1 0 0 1 1 1 0 IncA protein zf-CHCC PF10276.4 CDO71583.1 - 8.7e-09 35.0 0.1 1.3e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Zinc-finger domain Pkinase PF00069.20 CDO71584.1 - 5.3e-55 186.3 0.0 9e-55 185.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71584.1 - 1.3e-21 76.8 0.0 2.7e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pribosyl_synth PF14572.1 CDO71585.1 - 5e-40 137.2 3.8 9.6e-35 119.9 0.5 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CDO71585.1 - 8.5e-39 131.8 0.6 1.1e-37 128.3 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CDO71585.1 - 1.4e-10 40.9 0.2 3.2e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CDO71585.1 - 0.00074 18.7 0.1 0.0015 17.7 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RdRP PF05183.7 CDO71585.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase FAD_binding_4 PF01565.18 CDO71586.1 - 4.5e-17 61.8 1.8 9.2e-17 60.8 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain DCP2 PF05026.8 CDO71587.1 - 2.5e-34 117.0 1.4 4.2e-34 116.3 1.0 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 CDO71587.1 - 3.6e-13 49.3 0.0 6.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Rad21_Rec8_N PF04825.8 CDO71589.1 - 7.9e-15 54.7 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CDO71589.1 - 5e-11 41.6 0.0 1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CDO71589.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 ScpA/B protein NUDIX PF00293.23 CDO71590.1 - 3.5e-27 94.6 0.0 5.3e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MPC PF03650.8 CDO71594.1 - 1.4e-38 131.5 0.5 1.6e-38 131.3 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DNA_ligase_A_M PF01068.16 CDO71595.1 - 9.4e-64 214.5 0.2 1.4e-63 213.8 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CDO71595.1 - 1.9e-54 184.1 1.1 3.6e-54 183.2 0.8 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CDO71595.1 - 7.3e-27 93.6 0.0 2.3e-26 91.9 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CDO71595.1 - 0.002 17.7 0.1 0.51 10.0 0.0 2.7 2 0 0 2 2 2 2 DNA ligase OB-like domain Salp15 PF12115.3 CDO71595.1 - 0.093 12.9 0.0 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation TRAP_alpha PF03896.11 CDO71595.1 - 0.11 11.4 3.8 0.23 10.4 2.6 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CitMHS PF03600.11 CDO71597.1 - 0.047 12.2 4.0 0.022 13.3 1.2 1.6 1 1 1 2 2 2 0 Citrate transporter Ribosomal_S17 PF00366.15 CDO71598.1 - 8e-31 105.8 1.3 1.2e-30 105.3 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 OmdA PF13376.1 CDO71598.1 - 0.2 11.3 0.7 9.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Metallophos PF00149.23 CDO71599.1 - 4.5e-41 140.4 0.1 6.2e-41 139.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_S8 PF00082.17 CDO71600.1 - 1.8e-44 152.0 16.2 3.4e-44 151.0 11.2 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CDO71600.1 - 1.8e-09 38.0 0.0 1.3e-08 35.2 0.0 2.3 2 1 0 2 2 2 1 Peptidase inhibitor I9 EmrE PF13536.1 CDO71601.1 - 8.3e-07 29.2 4.8 8.3e-07 29.2 3.3 2.7 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 CDO71601.1 - 9.5 6.2 25.8 0.065 13.2 2.0 2.4 2 0 0 2 2 2 0 EamA-like transporter family RTA1 PF04479.8 CDO71602.1 - 4e-15 55.9 5.3 4.5e-12 45.9 0.3 2.0 2 0 0 2 2 2 2 RTA1 like protein RTA1 PF04479.8 CDO71603.1 - 6.6e-40 136.9 4.1 9.5e-40 136.4 2.8 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3149 PF11346.3 CDO71603.1 - 0.023 14.2 0.4 0.023 14.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Tic20 PF09685.5 CDO71603.1 - 5.1 7.1 11.0 0.19 11.7 0.5 2.6 1 1 0 2 2 2 0 Tic20-like protein SGS PF05002.10 CDO71604.1 - 4.2e-31 106.5 2.8 6.3e-31 105.9 2.0 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.11 CDO71604.1 - 9.4e-08 32.5 0.4 1.4e-07 31.9 0.0 1.5 2 0 0 2 2 2 1 CS domain Gifsy-2 PF13856.1 CDO71604.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage GST_N_3 PF13417.1 CDO71605.1 - 3e-12 46.6 0.1 7.4e-12 45.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO71605.1 - 2e-08 34.1 0.0 3.8e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO71605.1 - 0.0001 22.1 0.3 0.00036 20.3 0.1 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO71605.1 - 0.00051 19.9 0.0 0.0046 16.8 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CDO71605.1 - 0.0028 17.7 0.0 0.0067 16.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF4429 PF14472.1 CDO71605.1 - 0.014 15.6 0.0 0.53 10.6 0.0 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4429) Peptidase_C69 PF03577.10 CDO71605.1 - 0.037 12.9 0.0 0.065 12.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C69 DUF883 PF05957.8 CDO71605.1 - 0.094 13.1 0.5 1.8 9.0 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Galactosyl_T PF01762.16 CDO71606.1 - 6.8e-06 25.8 0.0 0.00056 19.5 0.0 2.6 3 0 0 3 3 3 2 Galactosyltransferase CsbD PF05532.7 CDO71609.1 - 0.049 13.3 1.6 0.11 12.2 1.1 1.5 1 0 0 1 1 1 0 CsbD-like OppC_N PF12911.2 CDO71611.1 - 0.38 10.1 4.0 1.1 8.7 2.8 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C ADH_zinc_N_2 PF13602.1 CDO71612.1 - 8.6e-20 71.9 0.0 1.2e-19 71.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Isochorismatase PF00857.15 CDO71613.1 - 9.3e-24 84.2 0.0 1.7e-23 83.4 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family SKG6 PF08693.5 CDO71614.1 - 0.17 11.2 2.4 0.49 9.7 1.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.1 CDO71614.1 - 8.4 6.5 0.0 8.4 6.5 0.0 5.1 4 2 2 6 6 6 0 Wnt and FGF inhibitory regulator Ras PF00071.17 CDO71615.1 - 1.8e-14 53.4 0.2 2.3e-14 53.0 0.2 1.1 1 0 0 1 1 1 1 Ras family KaiC PF06745.8 CDO71615.1 - 0.00021 20.4 0.0 0.00025 20.2 0.0 1.1 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 CDO71615.1 - 0.00058 20.0 0.0 0.0007 19.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CDO71615.1 - 0.00076 19.9 0.1 0.00091 19.7 0.1 1.1 1 0 0 1 1 1 1 Miro-like protein NACHT PF05729.7 CDO71615.1 - 0.0015 18.2 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CDO71615.1 - 0.0065 16.4 0.1 0.0075 16.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Arf PF00025.16 CDO71615.1 - 0.0094 15.2 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Septin PF00735.13 CDO71615.1 - 0.01 14.8 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 0 Septin Methyltransf_25 PF13649.1 CDO71615.1 - 0.011 16.0 0.1 0.018 15.4 0.0 1.4 2 0 0 2 2 1 0 Methyltransferase domain DUF2075 PF09848.4 CDO71615.1 - 0.014 14.4 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 CDO71615.1 - 0.017 14.5 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 CDO71615.1 - 0.023 13.9 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein DAP3 PF10236.4 CDO71615.1 - 0.03 13.2 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 CDO71615.1 - 0.03 14.6 0.1 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 CDO71615.1 - 0.03 13.7 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CDO71615.1 - 0.044 13.0 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 CDO71615.1 - 0.055 13.1 0.0 0.055 13.1 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase AAA_30 PF13604.1 CDO71615.1 - 0.06 12.9 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CDO71615.1 - 0.083 12.4 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CDO71615.1 - 0.085 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CDO71615.1 - 0.096 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 CDO71615.1 - 0.12 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 CDO71615.1 - 0.13 12.1 0.1 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 CDO71615.1 - 0.15 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Peptidase_S8 PF00082.17 CDO71616.1 - 1.3e-15 57.3 0.4 1.4e-15 57.2 0.3 1.0 1 0 0 1 1 1 1 Subtilase family D-ser_dehydrat PF14031.1 CDO71617.1 - 4.3e-19 68.4 0.0 9.7e-18 64.1 0.0 2.4 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 CDO71617.1 - 1e-14 54.6 0.1 1.5e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Abhydrolase_3 PF07859.8 CDO71618.1 - 1.2e-42 145.9 0.0 1.7e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDO71618.1 - 4.6e-05 22.7 0.0 0.00029 20.1 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 CDO71618.1 - 0.0089 14.7 1.5 1.9 7.1 0.1 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 CDO71618.1 - 0.018 14.7 0.0 0.036 13.8 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase_phd PF10503.4 CDO71618.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase IlvN PF07991.7 CDO71619.1 - 3.3e-51 172.9 0.1 4.8e-51 172.3 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain RRM_1 PF00076.17 CDO71619.1 - 1.1e-43 146.6 0.0 4.8e-21 74.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO71619.1 - 7.2e-33 112.3 0.0 4e-15 55.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO71619.1 - 3.1e-27 94.1 0.0 1.8e-11 43.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 CDO71619.1 - 9.7e-20 70.6 0.2 2.3e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein F420_oxidored PF03807.12 CDO71619.1 - 3e-11 43.5 0.1 6.7e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CDO71619.1 - 7.8e-07 29.0 0.0 1.8e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RRM_3 PF08777.6 CDO71619.1 - 9.9e-06 25.3 0.1 0.0028 17.4 0.0 2.8 2 0 0 2 2 2 1 RNA binding motif 2-Hacid_dh_C PF02826.14 CDO71619.1 - 3.8e-05 22.9 0.0 6.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CDO71619.1 - 0.0009 19.0 0.1 0.0058 16.3 0.1 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 CDO71619.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PDH PF02153.12 CDO71619.1 - 0.095 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase adh_short_C2 PF13561.1 CDO71620.1 - 3.3e-20 72.9 0.0 5.3e-20 72.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO71620.1 - 2.4e-16 60.0 0.0 4.1e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO71620.1 - 8.1e-05 22.3 0.0 0.00037 20.2 0.0 1.9 1 1 0 1 1 1 1 KR domain Cupin_2 PF07883.6 CDO71621.1 - 0.00025 20.4 0.0 0.0014 18.0 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Pex16 PF08610.5 CDO71622.1 - 1.2e-72 244.7 0.2 1.4e-72 244.4 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Bcl-2 PF00452.14 CDO71623.1 - 0.017 15.2 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Birna_RdRp PF04197.7 CDO71623.1 - 0.12 10.4 2.9 0.16 9.9 2.0 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF947 PF06102.7 CDO71624.1 - 3.1e-35 121.4 22.4 3.1e-35 121.4 14.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF947) CorA PF01544.13 CDO71624.1 - 4.6e-19 68.5 10.0 1.2e-12 47.5 0.1 3.5 3 1 0 3 3 3 2 CorA-like Mg2+ transporter protein Ninjurin PF04923.7 CDO71624.1 - 0.06 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Ninjurin LCD1 PF09798.4 CDO71624.1 - 2 6.3 4.7 3.3 5.6 3.3 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein Zip PF02535.17 CDO71624.1 - 4.7 6.1 6.3 0.6 9.0 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter FMN_red PF03358.10 CDO71625.1 - 4.8e-24 84.5 0.0 7.9e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CDO71625.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold DUF2235 PF09994.4 CDO71627.1 - 2.3e-24 86.2 0.1 5.4e-24 85.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SNAP PF14938.1 CDO71628.1 - 8.8e-107 356.4 16.7 1e-106 356.2 11.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 CDO71628.1 - 2.7e-06 26.7 8.6 0.011 15.4 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDO71628.1 - 1.8e-05 24.5 14.8 1.9e-05 24.5 4.1 3.5 1 1 3 4 4 4 1 Tetratricopeptide repeat Spatacsin_C PF14649.1 CDO71628.1 - 0.00011 21.2 6.6 0.00076 18.4 4.3 2.1 1 1 0 1 1 1 1 Spatacsin C-terminus TPR_11 PF13414.1 CDO71628.1 - 0.002 17.7 18.6 0.011 15.3 0.7 4.2 3 2 1 4 4 4 2 TPR repeat TPR_6 PF13174.1 CDO71628.1 - 0.0078 16.6 10.7 2.1 8.9 0.0 5.8 4 2 2 6 6 6 1 Tetratricopeptide repeat TC1 PF15063.1 CDO71628.1 - 0.02 14.4 0.3 0.057 12.9 0.2 1.9 1 0 0 1 1 1 0 Thyroid cancer protein 1 TPR_8 PF13181.1 CDO71628.1 - 0.032 13.9 9.9 0.13 12.0 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4351 PF14261.1 CDO71628.1 - 0.071 12.9 0.2 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) Foie-gras_1 PF11817.3 CDO71628.1 - 0.27 10.6 6.4 0.57 9.6 4.4 1.5 1 1 0 1 1 1 0 Foie gras liver health family 1 PerC PF06069.6 CDO71628.1 - 0.36 10.9 2.7 5.7 7.0 0.0 2.7 1 1 1 2 2 2 0 PerC transcriptional activator TPR_2 PF07719.12 CDO71628.1 - 0.46 10.5 20.1 1.4 8.9 0.7 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat PGM_PMM_II PF02879.11 CDO71629.1 - 6.2e-13 48.9 0.0 1.8e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 CDO71629.1 - 4.9e-11 42.2 0.0 2.4e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 CDO71629.1 - 1.9e-09 37.3 0.6 4.6e-09 36.1 0.1 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GATase_4 PF13230.1 CDO71630.1 - 3.6e-18 65.2 0.0 6.7e-18 64.3 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.16 CDO71630.1 - 5.2e-07 28.6 0.0 0.00023 19.9 0.0 2.3 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CDO71630.1 - 6.4e-07 29.3 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DS PF01916.12 CDO71631.1 - 1.9e-45 155.2 0.1 2.2e-45 155.0 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase APH PF01636.18 CDO71632.1 - 1.3e-17 64.3 0.0 8.3e-17 61.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 CDO71632.1 - 0.0014 17.3 0.0 0.0061 15.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) RIO1 PF01163.17 CDO71632.1 - 0.012 14.9 0.0 0.029 13.7 0.0 1.6 1 1 0 1 1 1 0 RIO1 family GATase_4 PF13230.1 CDO71633.1 - 1.8e-09 36.6 0.0 3.6e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II ICE2 PF08426.5 CDO71634.1 - 7.2e-25 87.4 24.4 2.3e-13 49.5 8.3 3.0 1 1 2 3 3 3 3 ICE2 MoaE PF02391.12 CDO71635.1 - 3.7e-28 97.6 1.1 1.8e-20 72.9 0.3 2.3 1 1 1 2 2 2 2 MoaE protein Indigoidine_A PF04227.7 CDO71636.1 - 1.1e-120 402.2 0.0 1.9e-120 401.5 0.0 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 CDO71636.1 - 3.5e-20 72.3 0.4 1.9e-09 37.1 0.0 2.7 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Helicase_C PF00271.26 CDO71637.1 - 1.2e-14 53.9 0.0 3e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO71637.1 - 0.00019 21.3 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CDO71637.1 - 0.039 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mito_carr PF00153.22 CDO71638.1 - 3.7e-66 218.8 5.7 2.7e-24 84.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_88 PF07470.8 CDO71638.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 CS PF04969.11 CDO71639.1 - 7.6e-19 68.0 0.1 2.8e-18 66.2 0.1 1.9 2 0 0 2 2 2 1 CS domain DUF3006 PF11213.3 CDO71640.1 - 0.0031 17.2 0.0 3.2 7.5 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3006) DUF2187 PF09953.4 CDO71640.1 - 0.0069 16.0 0.1 19 5.0 0.0 3.4 4 0 0 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2187) LTD PF00932.14 CDO71640.1 - 0.0071 16.4 1.0 1.2 9.2 0.0 2.9 1 1 2 3 3 3 1 Lamin Tail Domain His_leader PF08047.6 CDO71640.1 - 3.9 6.9 10.3 9.6 5.7 1.2 2.5 2 0 0 2 2 2 0 Histidine operon leader peptide NUC153 PF08159.7 CDO71641.1 - 7.5e-10 38.2 0.5 7.5e-10 38.2 0.3 3.8 3 0 0 3 3 3 2 NUC153 domain Tim17 PF02466.14 CDO71643.1 - 1.1e-09 38.4 13.1 1.8e-09 37.7 9.1 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_S9 PF00380.14 CDO71644.1 - 1.6e-35 121.9 0.5 1.6e-35 121.9 0.4 1.8 2 0 0 2 2 1 1 Ribosomal protein S9/S16 BRCT PF00533.21 CDO71644.1 - 8e-07 29.1 0.0 1.1e-05 25.4 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain YL1 PF05764.8 CDO71644.1 - 9.8e-05 22.0 9.8 9.8e-05 22.0 6.8 1.7 2 0 0 2 2 2 1 YL1 nuclear protein Daxx PF03344.10 CDO71644.1 - 0.00053 18.6 5.1 0.00093 17.8 3.5 1.4 1 0 0 1 1 1 1 Daxx Family Nucleoplasmin PF03066.10 CDO71644.1 - 0.062 12.8 5.2 0.13 11.7 3.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin Menin PF05053.8 CDO71644.1 - 0.2 9.8 2.6 0.36 8.9 1.8 1.3 1 0 0 1 1 1 0 Menin DUF2890 PF11081.3 CDO71644.1 - 1.1 9.2 16.5 0.026 14.5 6.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 CDO71644.1 - 1.3 6.8 16.4 0.088 10.7 7.9 1.5 2 0 0 2 2 2 0 Nop14-like family Apt1 PF10351.4 CDO71644.1 - 2.3 7.0 5.5 3.8 6.2 3.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIF_alpha PF05793.7 CDO71644.1 - 2.6 6.3 19.8 4.2 5.6 13.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 CDO71644.1 - 8.7 4.2 12.3 13 3.6 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 CDO71644.1 - 9.3 5.2 16.7 16 4.5 11.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ribosomal_L4 PF00573.17 CDO71645.1 - 9.1e-65 217.6 0.0 1e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF697 PF05128.7 CDO71645.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF697) Rad51 PF08423.6 CDO71646.1 - 6.4e-133 441.4 0.0 8.1e-133 441.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CDO71646.1 - 3.5e-13 49.3 0.0 5e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 CDO71646.1 - 5.2e-10 39.3 0.7 5.2e-10 39.3 0.5 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 CDO71646.1 - 5.2e-09 35.6 0.0 6.4e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CDO71646.1 - 1.6e-05 24.1 0.0 3.2e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 KaiC HHH PF00633.18 CDO71646.1 - 0.027 14.1 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif 2-Hacid_dh_C PF02826.14 CDO71647.1 - 1.4e-53 180.6 0.0 2.8e-53 179.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CDO71647.1 - 6.9e-34 116.1 0.0 9.6e-34 115.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CDO71647.1 - 0.00017 21.4 0.2 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 CDO71647.1 - 0.0053 16.6 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2597 PF10772.4 CDO71647.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) GATase PF00117.23 CDO71648.1 - 1.6e-26 92.9 0.0 2.5e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I His_biosynth PF00977.16 CDO71648.1 - 1.3e-15 57.3 0.3 3.2e-15 56.0 0.2 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein SNO PF01174.14 CDO71648.1 - 1.4e-08 34.5 0.0 1.5e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 CDO71648.1 - 3.1e-07 30.0 0.0 5.9e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 CDO71648.1 - 0.024 14.0 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 Pal1 PF08316.6 CDO71649.1 - 2.4e-15 57.1 0.1 7e-15 55.7 0.1 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein Meth_synt_2 PF01717.13 CDO71650.1 - 1.8e-09 37.0 0.0 2.6e-08 33.2 0.0 2.5 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CDO71650.1 - 8.1e-06 25.3 0.0 0.026 13.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Thioredoxin_3 PF13192.1 CDO71650.1 - 0.024 14.4 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin domain Ribosomal_L13e PF01294.13 CDO71651.1 - 9.1e-68 227.2 4.1 1.3e-67 226.7 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e FA_desaturase PF00487.19 CDO71652.1 - 4.8e-33 114.6 26.4 6.6e-33 114.2 18.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CDO71652.1 - 2.5e-09 36.7 0.2 6.8e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Sugar_tr PF00083.19 CDO71653.1 - 0.0015 17.1 1.1 0.013 14.1 0.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Herpes_gE PF02480.11 CDO71653.1 - 0.0026 16.0 0.1 0.0039 15.5 0.1 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1180 PF06679.7 CDO71653.1 - 0.0084 16.0 1.9 0.023 14.5 1.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Amnionless PF14828.1 CDO71653.1 - 0.23 9.9 0.0 0.33 9.4 0.0 1.1 1 0 0 1 1 1 0 Amnionless CAP_N PF01213.14 CDO71654.1 - 0.7 9.1 6.4 1.3 8.2 4.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal WD40 PF00400.27 CDO71656.1 - 2.8e-59 195.0 22.2 3.7e-11 42.4 0.5 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CDO71656.1 - 4.1e-33 114.4 0.0 1.1e-32 113.0 0.0 1.7 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 CDO71656.1 - 0.00083 19.1 0.0 0.0039 16.9 0.0 2.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 CDO71656.1 - 0.0065 16.2 0.1 0.025 14.3 0.0 2.0 2 0 0 2 2 2 1 LisH Cytochrom_D1 PF02239.11 CDO71656.1 - 0.012 13.9 0.0 0.02 13.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain MANEC PF07502.9 CDO71658.1 - 0.022 14.7 0.9 0.058 13.3 0.6 1.6 1 0 0 1 1 1 0 MANEC domain MSA_2 PF00985.12 CDO71658.1 - 0.11 12.6 0.2 0.18 11.9 0.2 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family FRG2 PF15315.1 CDO71659.1 - 0.023 14.6 4.7 0.029 14.3 3.2 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 NOA36 PF06524.7 CDO71659.1 - 5 6.2 5.5 5.9 6.0 3.8 1.1 1 0 0 1 1 1 0 NOA36 protein SH3_1 PF00018.23 CDO71661.1 - 3.2e-08 32.8 0.0 5.3e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CDO71661.1 - 3.8e-06 26.3 0.0 7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CDO71661.1 - 0.0005 19.5 0.0 0.0013 18.1 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain AJAP1_PANP_C PF15298.1 CDO71661.1 - 0.026 14.4 0.0 0.026 14.4 0.0 2.5 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Adeno_E3_CR2 PF02439.10 CDO71661.1 - 0.3 10.6 3.9 0.51 9.9 2.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FYRN PF05964.9 CDO71663.1 - 4.2e-16 58.1 0.1 6.6e-16 57.5 0.1 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 CDO71663.1 - 1.3e-15 56.9 0.0 2.6e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus CN_hydrolase PF00795.17 CDO71664.1 - 4.8e-13 48.8 0.0 6.6e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aft1_HRA PF11786.3 CDO71665.1 - 0.028 14.6 0.1 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Aft1 HRA domain BHD_3 PF10405.4 CDO71667.1 - 2.9e-26 90.9 0.1 5.2e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 CDO71667.1 - 9.3e-26 89.9 0.1 3.6e-25 88.0 0.0 2.1 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 CDO71667.1 - 1.9e-17 62.4 0.0 4.4e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CDO71667.1 - 5.1e-15 55.5 0.6 2.8e-14 53.1 0.1 2.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CDO71667.1 - 2.8e-08 33.9 0.0 2.4e-06 27.7 0.0 2.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily GCD14 PF08704.5 CDO71668.1 - 1.1e-70 237.9 0.2 6.3e-65 219.0 0.0 2.5 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 CDO71668.1 - 6.4e-07 29.4 0.0 1.6e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO71668.1 - 1.3e-06 28.9 0.0 2.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO71668.1 - 3.2e-05 23.5 0.0 5.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CDO71668.1 - 4.3e-05 23.1 0.0 7.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 CDO71668.1 - 0.00011 22.9 0.1 0.00027 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDO71668.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 CDO71668.1 - 0.005 15.8 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 CDO71668.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Fibrillarin PF01269.12 CDO71668.1 - 0.035 13.0 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_12 PF08242.7 CDO71668.1 - 0.073 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CDO71668.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PAS_3 PF08447.6 CDO71669.1 - 3.1e-07 30.3 0.0 6.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 CDO71669.1 - 7e-06 25.7 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 CDO71669.1 - 0.00053 19.9 0.0 0.0041 17.0 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.1 CDO71669.1 - 0.00069 19.9 0.0 0.0022 18.3 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 CDO71669.1 - 0.08 12.9 0.0 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 PAS fold THRAP3_BCLAF1 PF15440.1 CDO71669.1 - 3.8 6.0 7.6 5.3 5.5 5.2 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Helicase_C PF00271.26 CDO71670.1 - 5e-11 42.2 0.0 6e-08 32.4 0.0 3.2 4 0 0 4 4 4 2 Helicase conserved C-terminal domain HAD_2 PF13419.1 CDO71671.1 - 4.9e-14 52.9 0.0 7.3e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDO71671.1 - 1.1e-13 52.0 0.0 8.7e-13 49.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CDO71671.1 - 4.6e-10 39.0 0.0 1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CDO71671.1 - 0.015 15.5 0.0 0.039 14.1 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HABP4_PAI-RBP1 PF04774.10 CDO71671.1 - 0.33 11.4 0.2 0.33 11.4 0.1 2.3 3 0 0 3 3 3 0 Hyaluronan / mRNA binding family Linker_histone PF00538.14 CDO71672.1 - 3.5e-05 23.8 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family Ribonuc_L-PSP PF01042.16 CDO71673.1 - 7.5e-35 119.3 0.0 8.2e-35 119.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP p450 PF00067.17 CDO71675.1 - 5.7e-78 262.4 0.0 6.9e-78 262.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FlgN PF05130.7 CDO71676.1 - 0.0065 16.7 1.1 0.0096 16.1 0.7 1.2 1 0 0 1 1 1 1 FlgN protein Filo_VP35 PF02097.10 CDO71676.1 - 0.0085 15.3 0.3 0.012 14.8 0.2 1.1 1 0 0 1 1 1 1 Filoviridae VP35 PilJ PF13675.1 CDO71676.1 - 0.021 15.1 0.7 0.037 14.3 0.5 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term CHASE3 PF05227.8 CDO71676.1 - 0.026 14.2 0.7 0.051 13.2 0.5 1.5 1 1 0 1 1 1 0 CHASE3 domain Seryl_tRNA_N PF02403.17 CDO71676.1 - 0.034 14.1 0.8 0.054 13.5 0.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 CDO71676.1 - 0.04 14.1 1.1 0.12 12.6 0.5 1.9 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spore_YpjB PF09577.5 CDO71676.1 - 0.043 13.3 0.1 0.057 12.9 0.1 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) FUSC PF04632.7 CDO71676.1 - 0.052 11.9 0.9 0.072 11.5 0.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin PF00804.20 CDO71676.1 - 0.052 13.7 1.4 0.092 12.9 0.9 1.4 1 1 0 1 1 1 0 Syntaxin DUF3782 PF12644.2 CDO71676.1 - 0.081 12.7 0.2 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) BLOC1_2 PF10046.4 CDO71676.1 - 0.1 12.7 0.7 0.5 10.5 0.4 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 CDO71676.1 - 0.41 10.1 2.1 4 6.9 1.3 2.5 1 1 2 3 3 3 0 Septum formation initiator Carn_acyltransf PF00755.15 CDO71679.1 - 1.6e-166 554.9 0.0 1.9e-166 554.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PUL PF08324.6 CDO71680.1 - 6.5e-27 93.9 0.1 1.1e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 CDO71680.1 - 7.5e-24 84.2 0.0 1.1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 CDO71680.1 - 2.7e-16 59.1 0.0 6.2e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CDO71680.1 - 6e-07 29.6 0.0 3.7e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 CDO71680.1 - 0.0082 16.1 0.0 0.11 12.4 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin Redoxin PF08534.5 CDO71680.1 - 0.064 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.19 CDO71680.1 - 0.081 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin p450 PF00067.17 CDO71681.1 - 1.5e-50 172.1 0.0 1.8e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 POP1 PF06978.6 CDO71682.1 - 1.5e-49 168.2 18.5 2.5e-28 98.9 1.9 2.7 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CDO71682.1 - 4.6e-30 103.2 0.2 1.3e-29 101.9 0.1 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.16 CDO71682.1 - 9.8e-05 21.8 0.1 0.011 15.1 0.0 3.2 4 0 0 4 4 4 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CDO71682.1 - 0.064 13.2 0.0 0.31 11.0 0.0 2.2 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Tmemb_14 PF03647.8 CDO71682.1 - 0.072 13.5 0.1 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Transmembrane proteins 14C DUF2569 PF10754.4 CDO71683.1 - 4.2 7.5 9.9 1 9.5 2.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2569) D123 PF07065.9 CDO71684.1 - 9e-75 251.5 0.0 1.1e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 CDO71684.1 - 0.022 14.6 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Exo_endo_phos PF03372.18 CDO71685.1 - 6.2e-10 39.4 0.3 1e-09 38.7 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mito_carr PF00153.22 CDO71688.1 - 4.9e-75 247.3 0.2 4.7e-25 87.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Bacteriocin_IId PF09221.5 CDO71688.1 - 0.011 15.5 0.2 7.9 6.4 0.0 3.2 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like DUF427 PF04248.7 CDO71689.1 - 3.5e-21 74.6 0.6 7.5e-18 63.9 0.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF427) DUF2104 PF09877.4 CDO71690.1 - 0.14 12.0 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) 3Beta_HSD PF01073.14 CDO71693.1 - 2.1e-62 210.3 0.0 6e-59 199.0 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CDO71693.1 - 9.1e-36 123.4 0.0 1.3e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO71693.1 - 3.5e-17 62.9 0.0 5.3e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CDO71693.1 - 4e-17 61.9 0.0 2.3e-12 46.3 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 CDO71693.1 - 1.1e-11 44.1 0.0 1.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CDO71693.1 - 4.7e-05 22.4 0.1 0.00016 20.6 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CDO71693.1 - 0.0011 18.2 0.1 0.0067 15.7 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CDO71693.1 - 0.0023 17.8 0.5 0.0098 15.8 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Tim54 PF11711.3 CDO71693.1 - 0.0092 14.6 0.3 0.014 14.0 0.2 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 KR PF08659.5 CDO71693.1 - 0.015 14.9 0.1 0.03 14.0 0.0 1.6 1 1 0 1 1 1 0 KR domain Miro PF08477.8 CDO71695.1 - 6.5e-38 129.8 0.0 7.6e-19 68.3 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 CDO71695.1 - 2e-35 120.4 0.0 4.3e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 CDO71695.1 - 2.5e-32 109.9 0.2 4.6e-32 109.1 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 CDO71695.1 - 1.1e-31 109.4 0.0 7.4e-20 70.9 0.0 2.2 2 0 0 2 2 2 2 Ras family EF-hand_6 PF13405.1 CDO71695.1 - 1.3e-10 40.2 0.2 0.0002 20.9 0.0 3.0 3 0 0 3 3 2 2 EF-hand domain Arf PF00025.16 CDO71695.1 - 1.5e-10 40.5 0.0 0.0002 20.6 0.0 3.3 2 2 0 2 2 2 2 ADP-ribosylation factor family EF-hand_7 PF13499.1 CDO71695.1 - 4.3e-10 39.5 0.1 0.0013 18.8 0.0 2.9 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CDO71695.1 - 1.2e-09 36.7 1.2 0.00048 19.2 0.0 2.8 3 0 0 3 3 2 2 EF hand EF-hand_5 PF13202.1 CDO71695.1 - 1.6e-08 33.5 2.7 0.00036 19.7 0.1 2.6 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.18 CDO71695.1 - 1.6e-07 31.2 0.0 0.0064 16.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 CDO71695.1 - 4.2e-07 30.1 0.0 0.027 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CDO71695.1 - 6.2e-07 29.5 0.4 0.07 13.1 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain Dynamin_N PF00350.18 CDO71695.1 - 3.9e-06 26.7 1.2 0.15 11.8 0.0 3.3 2 1 1 3 3 3 2 Dynamin family EF-hand_10 PF14788.1 CDO71695.1 - 7.1e-06 25.5 1.1 0.0093 15.6 0.0 2.5 2 0 0 2 2 2 2 EF hand MobB PF03205.9 CDO71695.1 - 1.9e-05 24.4 0.0 0.22 11.1 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CDO71695.1 - 4.6e-05 23.7 0.0 0.29 11.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 CDO71695.1 - 4.7e-05 22.8 0.1 0.044 13.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.1 CDO71695.1 - 8.9e-05 22.1 0.0 0.27 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 CDO71695.1 - 0.0001 22.3 0.0 0.24 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATP_bind_1 PF03029.12 CDO71695.1 - 0.00014 21.5 1.3 2.4 7.6 0.0 4.1 4 0 0 4 4 4 1 Conserved hypothetical ATP binding protein NACHT PF05729.7 CDO71695.1 - 0.00014 21.5 0.0 0.4 10.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 CDO71695.1 - 0.00014 22.0 0.0 0.27 11.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CDO71695.1 - 0.00015 22.0 0.0 0.85 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CDO71695.1 - 0.00028 20.7 0.0 0.38 10.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CDO71695.1 - 0.00037 20.0 0.0 0.085 12.3 0.0 2.8 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation EF-hand_8 PF13833.1 CDO71695.1 - 0.00045 19.7 0.2 0.59 9.7 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair AAA_17 PF13207.1 CDO71695.1 - 0.00048 20.9 0.2 0.53 11.1 0.0 3.2 4 1 0 4 4 2 1 AAA domain DUF258 PF03193.11 CDO71695.1 - 0.00054 19.1 0.0 0.12 11.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Septin PF00735.13 CDO71695.1 - 0.00063 18.8 0.0 0.063 12.2 0.0 2.3 2 0 0 2 2 2 1 Septin RNA_helicase PF00910.17 CDO71695.1 - 0.00093 19.3 0.0 0.83 9.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SRPRB PF09439.5 CDO71695.1 - 0.001 18.3 0.0 0.95 8.6 0.0 2.5 3 0 0 3 3 2 1 Signal recognition particle receptor beta subunit SPARC_Ca_bdg PF10591.4 CDO71695.1 - 0.0014 18.6 0.2 0.39 10.7 0.0 2.9 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF815 PF05673.8 CDO71695.1 - 0.0029 16.5 0.1 0.38 9.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) G-alpha PF00503.15 CDO71695.1 - 0.0034 16.1 0.0 1.6 7.2 0.0 3.0 3 0 0 3 3 3 1 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 CDO71695.1 - 0.0037 16.7 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 CDO71695.1 - 0.0051 16.2 0.0 2 7.7 0.0 3.7 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain VirE PF05272.6 CDO71695.1 - 0.0069 15.8 0.0 3.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E AAA_23 PF13476.1 CDO71695.1 - 0.0097 16.2 0.1 1.7 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CDO71695.1 - 0.01 15.5 0.1 1.5 8.4 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase AAA_25 PF13481.1 CDO71695.1 - 0.011 15.0 0.0 0.43 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 CDO71695.1 - 0.013 15.0 0.0 0.41 10.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 CDO71695.1 - 0.016 14.9 0.0 0.65 9.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CDO71695.1 - 0.019 14.8 0.0 7.6 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CDO71695.1 - 0.027 13.9 0.0 0.52 9.7 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MCM PF00493.18 CDO71695.1 - 0.031 13.0 0.0 0.17 10.6 0.0 1.9 2 0 0 2 2 2 0 MCM2/3/5 family cobW PF02492.14 CDO71695.1 - 0.035 13.5 0.2 2.9 7.3 0.0 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 CDO71695.1 - 0.046 12.5 0.0 9.3 5.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AIG1 PF04548.11 CDO71695.1 - 0.067 12.2 0.0 0.28 10.2 0.0 2.0 2 0 0 2 2 2 0 AIG1 family Zeta_toxin PF06414.7 CDO71695.1 - 0.075 12.1 0.0 4.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.4 CDO71695.1 - 0.15 10.6 0.0 12 4.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Gtr1_RagA PF04670.7 CDO71695.1 - 0.16 11.1 0.1 10 5.1 0.0 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Guanylate_kin PF00625.16 CDO71695.1 - 0.16 11.3 0.1 0.55 9.6 0.0 1.9 2 0 0 2 2 1 0 Guanylate kinase Sigma54_activat PF00158.21 CDO71695.1 - 0.19 11.2 0.0 3.2 7.1 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain VWA_2 PF13519.1 CDO71696.1 - 1.4e-12 48.0 0.0 2.4e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CDO71696.1 - 5.5e-06 26.2 0.0 9.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 CDO71696.1 - 0.00045 19.3 0.0 0.00073 18.6 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A TRI5 PF06330.6 CDO71697.1 - 1.5e-06 27.1 0.0 1.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) NAGLU_C PF12972.2 CDO71697.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain XylR_N PF06505.6 CDO71697.1 - 0.068 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Activator of aromatic catabolism G-patch PF01585.18 CDO71698.1 - 0.054 13.2 0.6 0.054 13.2 0.4 2.3 3 0 0 3 3 3 0 G-patch domain Nbl1_Borealin_N PF10444.4 CDO71699.1 - 1.6e-08 33.7 0.6 3.3e-08 32.7 0.4 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal SASRP1 PF15160.1 CDO71699.1 - 0.026 13.7 2.2 0.047 12.9 1.5 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 MogR_DNAbind PF12181.3 CDO71699.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) RasGEF PF00617.14 CDO71700.1 - 3.4e-50 170.3 0.0 5.8e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CDO71700.1 - 1.9e-19 69.6 0.0 5.4e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 CDO71701.1 - 1.5e-14 53.2 0.0 2.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CDO71701.1 - 1.1e-13 50.3 0.0 1.9e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CDO71701.1 - 1.1e-12 47.1 0.0 1.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 CDO71701.1 - 0.062 13.4 0.1 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain NicO PF03824.11 CDO71702.1 - 5.9e-21 75.0 2.5 1e-18 67.6 0.0 2.5 2 0 0 2 2 2 2 High-affinity nickel-transport protein Vma12 PF11712.3 CDO71702.1 - 0.022 14.4 2.0 10 5.8 0.1 3.4 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4231 PF14015.1 CDO71702.1 - 0.067 13.1 3.5 0.74 9.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PMP1_2 PF08114.6 CDO71702.1 - 0.56 9.7 3.7 0.78 9.2 0.3 2.7 2 0 0 2 2 2 0 ATPase proteolipid family ATP_synt_I PF03899.10 CDO71702.1 - 2.2 8.4 13.4 2.7 8.1 0.3 3.5 3 0 0 3 3 3 0 ATP synthase I chain TRI5 PF06330.6 CDO71703.1 - 6.9e-07 28.2 0.0 8.4e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) PriCT_1 PF08708.6 CDO71703.1 - 0.019 14.7 0.4 20 5.1 0.0 3.7 4 0 0 4 4 4 0 Primase C terminal 1 (PriCT-1) Cyclin_N PF00134.18 CDO71704.1 - 2.3e-12 46.5 0.0 7.4e-11 41.7 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain PIG-U PF06728.8 CDO71705.1 - 1.6e-101 339.9 22.1 1.9e-101 339.7 15.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U p450 PF00067.17 CDO71706.1 - 1.3e-61 208.6 0.0 3e-47 161.2 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 TRI5 PF06330.6 CDO71707.1 - 8.9e-06 24.5 0.5 0.00013 20.7 0.0 2.4 3 0 0 3 3 3 2 Trichodiene synthase (TRI5) TRI5 PF06330.6 CDO71708.1 - 0.0039 15.8 0.4 0.024 13.2 0.1 2.2 2 1 0 2 2 2 1 Trichodiene synthase (TRI5) Filo_VP35 PF02097.10 CDO71708.1 - 0.095 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 TRI5 PF06330.6 CDO71709.1 - 0.012 14.2 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) DUF2779 PF11074.3 CDO71709.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) Mito_carr PF00153.22 CDO71710.1 - 4.3e-34 116.0 8.4 3.7e-13 48.9 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein NCA2 PF08637.5 CDO71712.1 - 2.4e-76 256.4 0.0 3.5e-76 255.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Glyco_hydro_61 PF03443.9 CDO71712.1 - 1e-48 166.0 0.0 1.8e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF937 PF06078.6 CDO71712.1 - 0.36 11.0 2.3 0.46 10.7 0.1 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF937) Glyco_hydro_61 PF03443.9 CDO71713.1 - 3.2e-68 229.8 0.1 4.4e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 CDO71713.1 - 7.1e-13 47.9 7.5 1.7e-12 46.7 5.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Mod_r PF07200.8 CDO71714.1 - 3.8e-23 82.0 4.4 1.5e-22 80.1 3.0 1.7 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Tropomyosin_1 PF12718.2 CDO71714.1 - 0.027 14.3 2.8 0.19 11.5 0.9 2.1 1 1 1 2 2 2 0 Tropomyosin like DUF2051 PF09738.4 CDO71714.1 - 0.039 13.2 0.1 0.063 12.5 0.0 1.3 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Rootletin PF15035.1 CDO71714.1 - 0.15 11.9 3.9 0.27 11.1 2.4 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 CDO71714.1 - 0.7 9.4 5.5 2.4 7.7 3.0 2.1 1 1 1 2 2 2 0 IncA protein NuA4 PF09340.5 CDO71715.1 - 2.5e-25 87.9 0.2 2.5e-25 87.9 0.2 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 GreA_GreB_N PF03449.10 CDO71715.1 - 3 7.9 6.7 0.21 11.6 0.7 1.9 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal AAA PF00004.24 CDO71716.1 - 1.5e-40 138.4 0.0 2.7e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDO71716.1 - 0.00025 21.0 0.1 0.012 15.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CDO71716.1 - 0.0013 18.7 0.1 0.011 15.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CDO71716.1 - 0.0017 17.4 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CDO71716.1 - 0.0027 17.4 0.2 0.021 14.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CDO71716.1 - 0.0036 17.4 0.5 0.1 12.7 0.3 2.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 CDO71716.1 - 0.0068 15.6 0.1 0.074 12.2 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 CDO71716.1 - 0.016 14.3 0.1 0.052 12.7 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CDO71716.1 - 0.026 14.2 0.1 0.066 12.9 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 CDO71716.1 - 0.026 13.9 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 CDO71716.1 - 0.03 15.1 0.0 0.15 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CDO71716.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CDO71716.1 - 0.053 13.0 0.1 0.91 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CDO71716.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CDO71716.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CDO71716.1 - 0.13 11.6 0.8 1.5 8.1 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CDO71716.1 - 0.15 11.6 0.1 0.52 9.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain 2-oxoacid_dh PF00198.18 CDO71717.1 - 3.2e-49 167.3 0.0 8.5e-49 165.8 0.0 1.6 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CDO71717.1 - 3.9e-18 64.8 0.0 6.8e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CDO71717.1 - 1.2e-11 43.9 0.2 2.6e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CDO71717.1 - 3.2e-06 26.6 0.1 1.5e-05 24.5 0.1 2.0 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 CDO71717.1 - 0.00039 20.7 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 CDO71717.1 - 0.036 13.2 0.0 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF21 PF01595.15 CDO71718.1 - 7.5e-25 87.2 0.7 2e-24 85.8 0.5 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CDO71718.1 - 2.8e-06 27.0 0.1 0.019 14.7 0.1 2.5 2 0 0 2 2 2 2 CBS domain DUF3433 PF11915.3 CDO71718.1 - 0.034 14.2 0.2 0.34 11.1 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3433) tRNA_U5-meth_tr PF05958.6 CDO71719.1 - 5.5e-15 54.9 0.0 1.8e-14 53.2 0.0 1.9 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 CDO71719.1 - 2.6e-08 33.9 0.3 1.1e-07 31.8 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CDO71719.1 - 1.2e-07 31.4 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 CDO71719.1 - 2.5e-07 31.2 0.0 5.8e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO71719.1 - 2.6e-07 30.3 0.0 3.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CDO71719.1 - 1.9e-05 24.3 0.0 3.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 CDO71719.1 - 0.00048 19.5 0.0 0.00096 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CDO71719.1 - 0.00055 20.3 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CDO71719.1 - 0.0015 17.9 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Met_10 PF02475.11 CDO71719.1 - 0.0023 17.5 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 CDO71719.1 - 0.0025 18.1 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CDO71719.1 - 0.0034 16.5 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 CDO71719.1 - 0.0067 16.8 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RsmJ PF04378.8 CDO71719.1 - 0.022 13.7 0.0 1.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Ribosomal RNA small subunit methyltransferase D, RsmJ Methyltransf_32 PF13679.1 CDO71719.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CDO71719.1 - 0.068 12.8 0.0 0.22 11.2 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain NodS PF05401.6 CDO71719.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 CDO71719.1 - 0.17 10.9 0.0 0.42 9.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase TRM PF02005.11 CDO71719.1 - 0.19 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase PS_Dcarbxylase PF02666.10 CDO71720.1 - 4.4e-77 257.9 0.0 5.4e-77 257.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DHC_N1 PF08385.7 CDO71721.1 - 2.2e-175 584.3 4.7 3.7e-110 369.0 0.2 3.2 2 1 1 3 3 3 3 Dynein heavy chain, N-terminal region 1 Gly_radical PF01228.16 CDO71721.1 - 0.092 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Glycine radical Pkinase PF00069.20 CDO71722.1 - 9e-55 185.6 0.0 3.2e-54 183.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71722.1 - 5.6e-27 94.4 0.1 2e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CDO71722.1 - 0.00017 20.6 0.1 0.0012 17.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CDO71722.1 - 0.0011 18.6 0.3 0.077 12.7 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CDO71722.1 - 0.0042 16.1 0.5 0.018 14.0 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CDO71722.1 - 0.035 13.4 0.0 0.085 12.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Med21 PF11221.3 CDO71723.1 - 1.4e-16 60.7 1.6 1.8e-16 60.4 1.1 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex PEP-utilisers_N PF05524.8 CDO71723.1 - 0.013 15.3 0.9 0.02 14.7 0.6 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal FlgN PF05130.7 CDO71723.1 - 0.035 14.3 0.1 0.046 13.9 0.1 1.1 1 0 0 1 1 1 0 FlgN protein DUF3391 PF11871.3 CDO71723.1 - 0.049 13.8 2.1 0.064 13.4 1.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DUF1662 PF07878.6 CDO71723.1 - 0.055 13.2 1.4 0.32 10.7 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1662) LOH1CR12 PF10158.4 CDO71723.1 - 0.07 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Tumour suppressor protein Occludin_ELL PF07303.8 CDO71723.1 - 0.079 13.6 0.1 0.094 13.4 0.0 1.2 1 0 0 1 1 1 0 Occludin homology domain Rtf2 PF04641.7 CDO71724.1 - 1.3e-72 244.0 0.3 1.7e-72 243.7 0.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 CDO71724.1 - 0.00088 18.7 0.1 0.018 14.5 0.0 2.6 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CDO71724.1 - 0.0037 16.9 0.1 0.041 13.6 0.0 2.5 1 1 1 2 2 2 1 RING-type zinc-finger MRP-S31 PF15433.1 CDO71724.1 - 2.5 7.4 5.9 0.42 9.9 1.5 1.5 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 HNH_2 PF13391.1 CDO71725.1 - 0.0026 17.4 0.1 0.008 15.9 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.11 CDO71726.1 - 3.2e-11 42.5 27.5 1.2e-10 40.7 18.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 CDO71726.1 - 2.2e-05 23.9 3.0 6.3e-05 22.5 2.1 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF1201 PF06716.6 CDO71726.1 - 0.0074 16.0 0.4 0.026 14.3 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1201) Pex14_N PF04695.8 CDO71726.1 - 0.12 12.4 5.5 0.41 10.6 2.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region gag_pre-integrs PF13976.1 CDO71726.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 GAG-pre-integrase domain OmpH PF03938.9 CDO71726.1 - 0.22 11.4 7.4 0.4 10.5 5.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TB2_DP1_HVA22 PF03134.14 CDO71727.1 - 4.3e-29 100.0 4.5 6.1e-29 99.6 3.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PgaD PF13994.1 CDO71727.1 - 0.88 9.0 3.7 1.9 7.9 2.6 1.6 1 1 0 1 1 1 0 PgaD-like protein UPF0197 PF05251.7 CDO71728.1 - 0.00038 20.7 6.6 0.00065 19.9 4.6 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0197) DUF3792 PF12670.2 CDO71728.1 - 0.089 12.6 2.1 0.11 12.3 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) NADH-u_ox-rdase PF10785.4 CDO71728.1 - 0.47 10.7 2.1 0.84 9.9 1.4 1.5 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4131 PF13567.1 CDO71728.1 - 3.3 7.0 6.3 3.6 6.9 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) QCR10 PF09796.4 CDO71728.1 - 4.8 6.9 7.5 9.9 5.9 0.9 2.3 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TFIIS_C PF01096.13 CDO71729.1 - 2.4e-17 62.2 9.4 3.1e-17 61.9 1.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CDO71729.1 - 4.3e-08 32.7 4.8 1.1e-06 28.2 0.2 2.8 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit UPF0547 PF10571.4 CDO71729.1 - 3.7e-05 23.3 5.9 0.17 11.6 0.1 3.3 3 0 0 3 3 3 1 Uncharacterised protein family UPF0547 DUF2387 PF09526.5 CDO71729.1 - 0.00014 21.6 4.6 0.097 12.6 0.2 2.4 2 1 0 2 2 2 2 Probable metal-binding protein (DUF2387) Baculo_LEF5_C PF11792.3 CDO71729.1 - 0.00019 20.7 0.6 0.00019 20.7 0.4 2.6 3 0 0 3 3 2 1 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.2 CDO71729.1 - 0.0002 21.0 7.8 0.0017 18.1 0.1 2.7 2 1 0 2 2 2 1 Double zinc ribbon IBR PF01485.16 CDO71729.1 - 0.00079 19.2 4.9 0.13 12.1 0.0 2.3 2 1 0 2 2 2 2 IBR domain zf-ribbon_3 PF13248.1 CDO71729.1 - 0.0013 17.9 14.5 0.029 13.5 2.7 3.6 3 1 1 4 4 4 3 zinc-ribbon domain zf-NADH-PPase PF09297.6 CDO71729.1 - 0.0017 17.8 8.8 0.012 15.0 2.0 2.9 2 1 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CDO71729.1 - 0.0018 18.0 11.0 0.016 14.9 0.6 3.3 2 1 1 3 3 3 1 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 CDO71729.1 - 0.0076 15.7 2.3 0.0076 15.7 1.6 3.2 3 1 0 3 3 3 1 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CDO71729.1 - 0.017 14.7 6.2 0.66 9.6 0.1 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF2296 PF10058.4 CDO71729.1 - 0.018 14.7 2.5 29 4.5 0.0 3.9 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C4pol PF14260.1 CDO71729.1 - 0.02 14.8 1.5 4.2 7.4 0.0 2.3 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF164 PF02591.10 CDO71729.1 - 0.023 14.4 1.8 13 5.6 0.0 3.4 3 0 0 3 3 3 0 Putative zinc ribbon domain PHD PF00628.24 CDO71729.1 - 0.035 13.7 8.2 0.33 10.6 0.3 2.8 2 1 1 3 3 3 0 PHD-finger DNA_RNApol_7kD PF03604.8 CDO71729.1 - 0.073 12.5 7.8 1.3 8.5 0.5 3.4 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-tcix PF14952.1 CDO71729.1 - 0.081 12.2 3.5 3.8 6.9 0.0 3.0 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding TF_Zn_Ribbon PF08271.7 CDO71729.1 - 0.089 12.1 17.5 0.065 12.5 2.7 3.5 2 2 0 2 2 2 0 TFIIB zinc-binding Terminase_GpA PF05876.7 CDO71729.1 - 0.096 11.0 4.1 0.84 7.9 0.7 2.2 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) DUF35_N PF12172.3 CDO71729.1 - 0.12 12.3 3.9 25 4.9 0.0 3.4 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Cytochrom_CIII PF02085.11 CDO71729.1 - 0.14 12.2 2.6 0.24 11.5 1.8 1.4 1 0 0 1 1 1 0 Class III cytochrome C family zf-RING_3 PF14369.1 CDO71729.1 - 0.18 11.8 5.1 20 5.3 0.0 3.6 3 1 1 4 4 4 0 zinc-finger HypA PF01155.14 CDO71729.1 - 0.18 11.4 6.0 0.9 9.2 0.1 2.4 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 CDO71729.1 - 0.19 11.6 13.4 2.7 7.9 0.1 4.0 3 1 0 3 3 3 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.11 CDO71729.1 - 0.24 11.1 7.3 3.1 7.5 0.3 2.8 3 0 0 3 3 2 0 NAD-dependent DNA ligase C4 zinc finger domain Nudix_N_2 PF14803.1 CDO71729.1 - 0.33 10.6 13.7 0.35 10.5 2.9 3.6 3 1 0 3 3 3 0 Nudix N-terminal Lar_restr_allev PF14354.1 CDO71729.1 - 0.34 11.2 10.8 6.4 7.1 1.0 3.1 1 1 0 2 2 2 0 Restriction alleviation protein Lar zf-UDP PF14569.1 CDO71729.1 - 0.34 10.6 4.8 0.21 11.3 0.2 2.5 1 1 2 3 3 3 0 Zinc-binding RING-finger PhnA_Zn_Ribbon PF08274.7 CDO71729.1 - 0.35 10.6 12.5 2.7 7.8 0.5 3.4 2 2 1 3 3 3 0 PhnA Zinc-Ribbon Zn_ribbon_recom PF13408.1 CDO71729.1 - 0.38 11.0 7.2 12 6.2 0.1 3.2 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zinc-ribbons_6 PF07191.7 CDO71729.1 - 0.41 10.4 6.7 1.9 8.3 0.1 2.5 2 1 0 2 2 2 0 zinc-ribbons zf-FPG_IleRS PF06827.9 CDO71729.1 - 0.85 9.3 5.9 9.3 6.0 0.1 3.2 2 1 1 3 3 3 0 Zinc finger found in FPG and IleRS A2L_zn_ribbon PF08792.5 CDO71729.1 - 1.7 8.2 13.3 2.2 7.8 0.1 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain Elf1 PF05129.8 CDO71729.1 - 1.8 8.3 7.9 0.84 9.3 1.1 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Ogr_Delta PF04606.7 CDO71729.1 - 2.1 8.0 6.7 5.6 6.7 0.4 3.2 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-ISL3 PF14690.1 CDO71729.1 - 3.1 7.8 7.4 12 6.0 0.0 3.5 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_5 PF13719.1 CDO71729.1 - 3.7 7.2 11.7 5 6.7 0.7 3.7 3 1 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.1 CDO71729.1 - 3.9 7.4 10.5 7.2 6.5 1.2 3.3 1 1 1 3 3 3 0 CpXC protein DUF329 PF03884.9 CDO71729.1 - 4.1 7.0 5.4 6.3 6.4 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF329) zf-DNA_Pol PF08996.5 CDO71729.1 - 4.7 6.5 6.7 1.2 8.4 0.9 2.2 1 1 0 2 2 2 0 DNA Polymerase alpha zinc finger Rpr2 PF04032.11 CDO71729.1 - 5.6 6.9 9.0 5.3e+02 0.5 6.2 3.0 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-LITAF-like PF10601.4 CDO71729.1 - 5.8 6.8 8.6 32 4.4 0.1 3.5 3 1 1 4 4 3 0 LITAF-like zinc ribbon domain Ribosomal_S27e PF01667.12 CDO71729.1 - 6.8 6.3 10.6 16 5.1 1.5 3.3 3 1 0 3 3 3 0 Ribosomal protein S27 zinc_ribbon_4 PF13717.1 CDO71729.1 - 7.8 6.2 11.7 14 5.4 0.9 3.8 3 1 1 4 4 4 0 zinc-ribbon domain zf-AN1 PF01428.11 CDO71729.1 - 8.7 6.3 7.7 9.2 6.2 0.6 3.0 3 0 0 3 3 3 0 AN1-like Zinc finger Peptidase_M1 PF01433.15 CDO71730.1 - 1.1e-34 120.2 0.0 3.6e-28 98.7 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 CDO71730.1 - 3.1e-14 53.1 0.1 4.5e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 CDO71730.1 - 0.052 13.5 2.6 0.92 9.4 1.8 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Cortex-I_coil PF09304.5 CDO71731.1 - 0.0091 16.0 8.7 0.013 15.5 1.5 2.2 1 1 0 2 2 2 1 Cortexillin I, coiled coil Pellino PF04710.9 CDO71731.1 - 0.088 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Pellino CENP-F_leu_zip PF10473.4 CDO71731.1 - 0.13 12.0 10.2 0.28 11.0 6.8 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hrs_helical PF12210.3 CDO71731.1 - 0.22 11.8 5.0 0.098 12.9 0.8 2.2 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Seryl_tRNA_N PF02403.17 CDO71731.1 - 0.83 9.6 7.1 0.21 11.6 1.3 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 CDO71731.1 - 1.6 7.7 8.4 0.42 9.6 3.7 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 CDO71731.1 - 3.2 6.0 5.9 3.4 5.9 4.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family GET2 PF08690.5 CDO71732.1 - 0.06 12.5 0.2 9.7 5.3 0.0 2.9 3 0 0 3 3 3 0 GET complex subunit GET2 CAML PF14963.1 CDO71732.1 - 0.28 10.5 0.2 0.41 9.9 0.2 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand L51_S25_CI-B8 PF05047.11 CDO71733.1 - 3.3e-10 39.5 0.1 6.3e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain YL1 PF05764.8 CDO71734.1 - 6.4e-24 84.8 18.5 9.5e-24 84.3 12.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein PepSY PF03413.14 CDO71734.1 - 0.029 15.0 0.7 22 5.7 0.0 3.3 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain APH PF01636.18 CDO71735.1 - 1.2e-11 44.7 0.2 2.9e-06 27.2 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF282 PF03380.9 CDO71735.1 - 0.049 13.3 0.1 0.049 13.3 0.1 2.3 3 0 0 3 3 3 0 Caenorhabditis protein of unknown function, DUF282 MutS_V PF00488.16 CDO71736.1 - 2e-66 223.8 0.2 3.7e-63 213.0 0.2 2.3 1 1 1 2 2 2 2 MutS domain V MutS_III PF05192.13 CDO71736.1 - 2.1e-22 79.9 9.6 6.4e-13 48.9 1.3 3.0 3 1 0 3 3 3 2 MutS domain III MutS_IV PF05190.13 CDO71736.1 - 2.2e-05 24.5 0.0 5.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV DAO PF01266.19 CDO71737.1 - 2.3e-16 59.6 0.1 2.8e-15 56.0 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CDO71737.1 - 0.00092 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDO71737.1 - 0.0031 16.6 0.1 0.0065 15.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CDO71737.1 - 0.0043 17.0 0.1 0.0092 15.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CDO71737.1 - 0.0046 15.8 0.0 0.0078 15.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 CDO71737.1 - 0.035 13.0 0.1 0.057 12.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 CDO71737.1 - 0.056 13.2 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CDO71737.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CDO71737.1 - 0.12 11.3 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) BCIP PF13862.1 CDO71738.1 - 4.9e-59 199.1 0.0 6.2e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Vps35 PF03635.12 CDO71739.1 - 0 1050.7 0.1 0 1050.5 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF1219 PF06755.7 CDO71739.1 - 0.035 13.6 0.3 0.19 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1219) RNA_pol_Rpb1_1 PF04997.7 CDO71740.1 - 5.6e-112 374.3 0.0 2.7e-67 227.4 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CDO71740.1 - 2.2e-105 351.8 0.0 3.4e-105 351.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CDO71740.1 - 7.4e-69 230.9 0.0 1.4e-68 230.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CDO71740.1 - 1.9e-68 229.9 0.0 4.2e-68 228.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 CDO71740.1 - 3.3e-49 166.6 0.0 1.1e-48 164.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 CDO71740.1 - 3.2e-44 149.9 0.7 6.4e-44 148.9 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 CDO71740.1 - 8.6e-36 121.9 0.0 1.8e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Tho2 PF11262.3 CDO71740.1 - 0.22 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 VHS PF00790.14 CDO71741.1 - 5.7e-46 155.6 0.5 1.1e-44 151.4 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 CDO71741.1 - 2.3e-19 69.0 6.9 3.8e-19 68.3 4.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 CDO71741.1 - 1.9e-06 27.7 4.7 3.7e-06 26.8 3.3 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger UIM PF02809.15 CDO71741.1 - 0.0021 17.4 15.6 0.014 14.8 1.6 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-C3HC4_2 PF13923.1 CDO71741.1 - 5.1 7.1 11.3 1.4 9.0 5.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Amidase PF01425.16 CDO71742.1 - 3.3e-92 309.6 0.0 3.8e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 Amidase Amidase PF01425.16 CDO71744.1 - 1e-98 331.0 0.0 3.6e-98 329.3 0.0 1.7 1 1 0 1 1 1 1 Amidase Pro_dh PF01619.13 CDO71746.1 - 2.9e-30 105.3 0.0 9.7e-15 54.3 0.1 3.6 1 1 0 2 2 2 2 Proline dehydrogenase Resolvase PF00239.16 CDO71746.1 - 0.017 14.9 1.5 0.28 11.0 0.0 2.8 3 0 0 3 3 3 0 Resolvase, N terminal domain Pro_dh PF01619.13 CDO71747.1 - 1.7e-26 92.9 0.0 1.5e-13 50.3 0.0 2.6 2 1 0 2 2 2 2 Proline dehydrogenase DUF773 PF05600.7 CDO71747.1 - 0.041 12.6 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF773) TIP120 PF08623.5 CDO71748.1 - 6.9e-52 175.4 0.8 5.3e-51 172.5 0.0 2.9 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 CDO71748.1 - 8.5e-23 78.3 22.3 0.01 15.8 0.0 14.4 16 0 0 16 16 15 5 HEAT repeat HEAT_2 PF13646.1 CDO71748.1 - 3.1e-21 75.4 14.1 5.6e-06 26.5 0.1 8.7 6 2 3 9 9 9 5 HEAT repeats Cnd1 PF12717.2 CDO71748.1 - 1.7e-14 54.0 0.7 0.00046 20.0 0.0 6.5 5 2 2 7 7 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CDO71748.1 - 5.5e-13 48.0 5.4 0.0014 17.0 0.0 5.0 3 2 1 4 4 4 3 Adaptin N terminal region HEAT_EZ PF13513.1 CDO71748.1 - 5.2e-12 45.8 21.1 1 9.9 0.0 12.6 10 2 4 14 14 14 3 HEAT-like repeat CLASP_N PF12348.3 CDO71748.1 - 2.7e-09 36.7 7.8 2e-06 27.3 0.0 5.5 5 1 1 6 6 6 2 CLASP N terminal UME PF08064.8 CDO71748.1 - 3.1e-06 27.0 4.7 3.8 7.5 0.0 5.3 5 0 0 5 5 4 2 UME (NUC010) domain MMS19_N PF14500.1 CDO71748.1 - 4.1e-06 26.2 0.5 0.44 9.7 0.0 5.4 5 1 0 6 6 6 1 Dos2-interacting transcription regulator of RNA-Pol-II Vac14_Fab1_bd PF12755.2 CDO71748.1 - 3.6e-05 24.0 0.9 4.8 7.6 0.1 6.5 7 2 1 8 8 7 1 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 CDO71748.1 - 0.005 16.6 3.8 1.5 8.7 0.1 4.8 4 1 0 4 4 4 1 Protein of unknown function (DUF2435) ParcG PF10274.4 CDO71748.1 - 0.05 13.5 5.9 51 3.6 0.0 5.7 6 0 0 6 6 6 0 Parkin co-regulated protein Tax PF02959.11 CDO71748.1 - 0.055 12.9 2.0 0.27 10.6 0.6 2.5 2 0 0 2 2 2 0 HTLV Tax DUF2457 PF10446.4 CDO71748.1 - 0.069 11.8 2.8 0.11 11.2 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) V-ATPase_H_C PF11698.3 CDO71748.1 - 0.15 11.9 2.4 21 5.0 0.0 4.9 6 0 0 6 6 5 0 V-ATPase subunit H BUD22 PF09073.5 CDO71748.1 - 0.67 8.9 2.7 1.3 8.0 1.9 1.3 1 0 0 1 1 1 0 BUD22 Nucleoplasmin PF03066.10 CDO71748.1 - 0.97 8.9 5.6 2 7.9 3.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin MMS19_C PF12460.3 CDO71748.1 - 1.7 7.3 26.3 1.8 7.1 0.3 5.9 3 2 1 5 5 5 0 RNAPII transcription regulator C-terminal AAA PF00004.24 CDO71750.1 - 6.9e-37 126.5 0.0 1.1e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CDO71750.1 - 7e-26 89.8 0.5 5.6e-25 87.0 0.1 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CDO71750.1 - 1.3e-22 79.3 7.4 1.3e-22 79.3 5.1 2.8 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_14 PF13173.1 CDO71750.1 - 0.011 15.6 0.6 0.032 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CDO71750.1 - 0.014 15.5 1.8 1 9.5 0.0 3.0 2 1 1 3 3 3 0 AAA domain ResIII PF04851.10 CDO71750.1 - 0.049 13.4 0.6 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 CDO71750.1 - 0.081 13.7 0.1 0.35 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.12 CDO71750.1 - 1.2 9.2 5.4 5.8 7.0 1.5 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 CDO71751.1 - 3.3e-62 209.9 0.0 4.3e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71751.1 - 8.2e-23 80.7 0.0 1.1e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO71751.1 - 7.5e-06 25.1 0.0 1.8e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Ribosomal_L19e PF01280.15 CDO71752.1 - 3.4e-62 208.6 11.7 3.4e-62 208.6 8.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.20 CDO71752.1 - 0.014 14.7 0.0 0.056 12.8 0.0 2.0 1 0 0 1 1 1 0 S4 domain DUF3049 PF11250.3 CDO71752.1 - 0.057 13.1 2.0 0.076 12.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3049) DUF349 PF03993.7 CDO71752.1 - 1.3 9.2 9.5 19 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) MOZ_SAS PF01853.13 CDO71753.1 - 1.8e-64 216.4 0.0 3.2e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CDO71753.1 - 4.4e-07 29.5 0.4 1.2e-06 28.1 0.3 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 CDO71753.1 - 0.063 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Agenet PF05641.7 CDO71753.1 - 0.072 13.2 0.4 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 Agenet domain Pkinase PF00069.20 CDO71755.1 - 2.8e-31 108.6 0.1 1.3e-24 86.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71755.1 - 9.1e-16 57.6 0.0 5e-15 55.2 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO71755.1 - 4.1e-05 22.6 0.0 6.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like F-box-like PF12937.2 CDO71756.1 - 3.8e-08 32.9 0.3 6.8e-08 32.1 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO71756.1 - 1.3e-06 27.8 0.1 2e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 F-box domain SAP30_Sin3_bdg PF13867.1 CDO71757.1 - 1.2e-08 34.6 0.3 3.5e-06 26.7 0.2 2.3 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Sel1 PF08238.7 CDO71758.1 - 1.1e-18 67.2 11.9 9e-07 29.3 0.1 3.8 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.1 CDO71758.1 - 0.035 14.8 0.6 1.4 9.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CDO71758.1 - 0.054 13.1 0.8 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 CDO71758.1 - 0.85 9.6 5.6 0.54 10.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PBP PF01161.15 CDO71759.1 - 1.5e-18 67.0 0.1 3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DDE_3 PF13358.1 CDO71760.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO71760.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Peptidase_S28 PF05577.7 CDO71761.1 - 1.4e-49 168.8 0.0 3.7e-49 167.4 0.0 1.6 1 1 1 2 2 2 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.15 CDO71761.1 - 0.028 13.9 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DNA_topoisoIV PF00521.15 CDO71762.1 - 2.5e-129 431.8 0.2 4.9e-129 430.8 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CDO71762.1 - 3.8e-36 123.9 0.5 3.8e-36 123.9 0.3 2.0 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 CDO71762.1 - 8.4e-15 54.5 0.0 3.4e-14 52.6 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CDO71762.1 - 5.9e-09 35.6 0.0 1.8e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF802 PF05650.6 CDO71763.1 - 4.6 7.4 10.7 2.2 8.4 5.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF802) LSM PF01423.17 CDO71764.1 - 1.4e-06 27.7 0.0 1.6e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CDO71764.1 - 0.028 14.3 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF4444 PF14563.1 CDO71764.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Kinocilin PF15033.1 CDO71764.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinocilin protein UPF0052 PF01933.13 CDO71765.1 - 3.5e-31 108.6 0.0 4.3e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF4147 PF13660.1 CDO71765.1 - 0.12 11.4 0.1 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Chorismate_synt PF01264.16 CDO71766.1 - 3.3e-67 226.4 0.0 4.6e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Chorismate synthase bZIP_1 PF00170.16 CDO71768.1 - 8.5e-12 44.8 14.4 1.5e-11 44.0 10.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.10 CDO71768.1 - 0.00082 18.8 2.3 0.0018 17.6 1.6 1.5 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.10 CDO71768.1 - 0.0016 18.1 14.5 0.0016 18.1 10.1 2.4 1 1 1 2 2 2 1 Basic region leucine zipper HTH_33 PF13592.1 CDO71768.1 - 0.075 12.5 0.9 0.49 9.9 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix Glutaredoxin2_C PF04399.8 CDO71768.1 - 0.13 11.7 1.9 0.31 10.6 1.2 1.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain TSC22 PF01166.13 CDO71768.1 - 0.35 10.8 3.9 1.9 8.5 2.7 2.1 1 1 0 1 1 1 0 TSC-22/dip/bun family V_ATPase_I PF01496.14 CDO71768.1 - 1.2 6.8 2.2 1.7 6.4 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.12 CDO71768.1 - 2.1 8.7 15.1 0.44 10.8 7.7 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Tmemb_cc2 PF10267.4 CDO71768.1 - 2.9 6.3 22.6 0.0081 14.7 7.2 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF972 PF06156.8 CDO71768.1 - 4.8 7.5 8.2 0.38 11.1 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Rab5-bind PF09311.6 CDO71770.1 - 0.016 15.0 2.4 0.055 13.3 0.3 2.1 2 0 0 2 2 2 0 Rabaptin-like protein DUF1409 PF07197.7 CDO71770.1 - 0.041 13.9 0.1 0.099 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) HeH PF12949.2 CDO71770.1 - 0.045 13.3 0.0 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 HeH/LEM domain Glyco_hydro_88 PF07470.8 CDO71771.1 - 6.4e-05 22.1 1.8 0.00052 19.1 0.9 2.0 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 DUF1708 PF08101.6 CDO71773.1 - 7.6e-16 57.9 0.0 1.1e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 CDO71773.1 - 0.051 13.1 0.0 0.39 10.3 0.0 2.3 3 0 0 3 3 3 0 RhoGAP domain Pro_isomerase PF00160.16 CDO71775.1 - 9.2e-40 136.3 0.2 1e-39 136.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD OPT PF03169.10 CDO71776.1 - 1.1e-197 658.3 63.9 1.3e-197 658.1 44.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PS_Dcarbxylase PF02666.10 CDO71777.1 - 4.8e-54 182.7 0.0 7.4e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 CDO71777.1 - 3.8e-35 119.5 0.4 1.6e-16 59.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_6 PF13405.1 CDO71777.1 - 0.05 13.5 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain CEP76-C2 PF15627.1 CDO71777.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 CEP76 C2 domain TBPIP PF07106.8 CDO71778.1 - 2.1e-31 108.7 0.1 2.6e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mito_carr PF00153.22 CDO71779.1 - 4.3e-54 180.1 0.3 2.9e-20 71.7 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 CDO71781.1 - 0.00045 19.8 0.0 0.0014 18.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO71781.1 - 0.007 15.9 0.0 0.13 12.0 0.0 2.9 3 0 0 3 3 3 1 F-box domain DDE_1 PF03184.14 CDO71784.1 - 5.9e-35 120.3 0.0 9.6e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CDO71784.1 - 1.1e-09 37.9 0.5 5.7e-09 35.6 0.1 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF1752 PF08550.5 CDO71785.1 - 2.9e-12 45.9 0.4 5.5e-12 45.0 0.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) F-box PF00646.28 CDO71786.1 - 6.9e-08 31.9 2.0 5.9e-05 22.5 0.0 3.1 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 CDO71786.1 - 3.7e-06 26.5 1.8 0.0018 17.9 0.0 3.2 3 0 0 3 3 3 2 F-box-like Fungal_trans PF04082.13 CDO71787.1 - 3.1e-33 114.7 0.0 4.8e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CDO71787.1 - 0.025 14.4 9.4 0.049 13.5 0.5 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 CDO71787.1 - 0.15 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain AAA PF00004.24 CDO71789.1 - 1.3e-13 51.2 0.0 2.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 CDO71789.1 - 9.5e-13 47.9 0.0 1.7e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_16 PF13191.1 CDO71789.1 - 2.4e-12 47.2 0.0 2.4e-11 43.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CDO71789.1 - 4.7e-07 29.9 0.0 8.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO71789.1 - 0.00012 21.7 0.0 0.00046 19.8 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CDO71789.1 - 0.0076 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CDO71789.1 - 0.0097 15.6 0.0 0.052 13.2 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 CDO71789.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) YL1 PF05764.8 CDO71789.1 - 0.02 14.5 3.9 0.035 13.7 2.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein AAA_17 PF13207.1 CDO71789.1 - 0.054 14.3 0.7 0.78 10.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 CDO71789.1 - 0.06 13.0 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 CDO71789.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CDO71789.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.1 CDO71789.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CDO71789.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus T2SE PF00437.15 CDO71789.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.9 CDO71789.1 - 0.22 10.4 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase PBP1_TM PF14812.1 CDO71789.1 - 1.8 8.9 8.7 6 7.2 6.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-box-like PF12937.2 CDO71790.1 - 0.00063 19.4 0.2 0.0016 18.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO71790.1 - 0.037 13.6 0.1 0.098 12.3 0.1 1.8 1 0 0 1 1 1 0 F-box domain CENP-B_dimeris PF09026.5 CDO71791.1 - 1.5 9.1 7.0 3.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MYT1 PF08474.6 CDO71794.1 - 0.018 14.5 2.4 0.022 14.2 1.7 1.1 1 0 0 1 1 1 0 Myelin transcription factor 1 Tir_receptor_N PF07490.6 CDO71794.1 - 0.069 12.7 0.3 0.069 12.7 0.2 1.9 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus APC_CDC26 PF10471.4 CDO71794.1 - 3.4 8.4 6.1 6.7 7.5 1.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 S10_plectin PF03501.10 CDO71797.1 - 1.5e-36 124.1 0.2 8e-33 112.1 0.0 2.1 2 0 0 2 2 2 2 Plectin/S10 domain TrmB PF01978.14 CDO71797.1 - 0.01 15.5 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB LRR_4 PF12799.2 CDO71798.1 - 1.4e-31 107.5 14.9 5.6e-09 35.4 0.9 8.9 8 2 3 11 11 11 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDO71798.1 - 5.4e-25 83.5 15.1 0.023 14.6 0.0 10.7 12 0 0 12 12 12 7 Leucine Rich Repeat LRR_8 PF13855.1 CDO71798.1 - 1.6e-20 72.5 20.7 5.3e-13 48.5 2.5 7.8 7 2 1 8 8 8 5 Leucine rich repeat LRR_6 PF13516.1 CDO71798.1 - 7e-19 65.7 14.3 0.09 12.8 0.2 11.0 12 0 0 12 12 12 6 Leucine Rich repeat LRR_7 PF13504.1 CDO71798.1 - 1.1e-14 51.9 31.4 0.081 13.1 0.5 10.8 11 0 0 11 11 11 7 Leucine rich repeat CBM_5_12 PF02839.9 CDO71799.1 - 9.8e-12 44.2 12.5 9.8e-12 44.2 8.6 2.9 3 0 0 3 3 3 2 Carbohydrate binding domain Oxidored_molyb PF00174.14 CDO71801.1 - 1.2e-52 177.7 0.0 1.8e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CDO71801.1 - 1.7e-20 72.9 0.6 3.1e-20 72.1 0.4 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Gmad2 PF10648.4 CDO71801.1 - 0.022 14.9 0.0 0.057 13.6 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination Serinc PF03348.10 CDO71802.1 - 1.2e-158 528.3 11.6 1.4e-158 528.1 8.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3661 PF12400.3 CDO71802.1 - 0.027 14.5 4.6 0.044 13.8 0.0 2.8 2 1 1 3 3 3 0 Vaculolar membrane protein FA_desaturase PF00487.19 CDO71802.1 - 6.8 6.0 19.3 0.67 9.3 6.0 3.3 2 1 1 3 3 3 0 Fatty acid desaturase Rad51 PF08423.6 CDO71803.1 - 5.3e-11 41.9 0.0 7.9e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CDO71803.1 - 9.5e-10 38.1 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CDO71803.1 - 1.6e-07 30.7 0.0 1.5e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 CDO71803.1 - 0.00064 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO71803.1 - 0.00065 19.4 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 CDO71803.1 - 0.0019 18.4 0.0 0.0061 16.7 0.0 2.0 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RecA PF00154.16 CDO71803.1 - 0.0029 16.7 0.0 0.0066 15.5 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_16 PF13191.1 CDO71803.1 - 0.0032 17.4 0.1 0.0078 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 CDO71803.1 - 0.024 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain CobU PF02283.11 CDO71803.1 - 0.031 13.6 0.0 0.41 10.0 0.0 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase PAXNEB PF05625.6 CDO71803.1 - 0.039 12.7 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 PAXNEB protein NB-ARC PF00931.17 CDO71803.1 - 0.056 12.2 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 CDO71803.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain Glyco_transf_22 PF03901.12 CDO71804.1 - 6e-34 117.7 15.3 7.3e-34 117.4 10.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family MFS_1 PF07690.11 CDO71805.1 - 9.3e-28 96.9 19.7 9.3e-28 96.9 13.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CDO71805.1 - 0.071 13.1 2.0 0.53 10.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) TMEM61 PF15105.1 CDO71805.1 - 0.13 11.7 0.3 0.23 10.9 0.2 1.3 1 0 0 1 1 1 0 TMEM61 protein family DIOX_N PF14226.1 CDO71806.1 - 3.1e-19 69.6 0.0 4.1e-18 66.0 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO71806.1 - 1.2e-10 41.5 0.0 2.6e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-MYND PF01753.13 CDO71807.1 - 3.2e-11 42.9 10.9 8.2e-11 41.5 7.5 1.7 1 0 0 1 1 1 1 MYND finger IDO PF01231.13 CDO71808.1 - 3.5e-113 378.2 0.0 4.6e-113 377.8 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TFIIF_beta PF02270.10 CDO71809.1 - 5.4e-47 160.8 0.0 2.2e-36 126.0 0.0 2.1 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 CDO71809.1 - 3.4e-06 26.6 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Nucleoplasmin PF03066.10 CDO71809.1 - 0.15 11.5 4.1 0.36 10.3 2.8 1.7 1 0 0 1 1 1 0 Nucleoplasmin Cytochrom_C PF00034.16 CDO71812.1 - 5.9e-10 39.8 0.2 1e-09 39.0 0.2 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CDO71812.1 - 1.8e-08 34.3 2.9 2.9e-07 30.5 2.0 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CDO71812.1 - 0.0058 16.0 0.2 0.055 12.9 0.0 2.2 2 1 0 2 2 2 1 Cytochrome c-550 domain MIS13 PF08202.6 CDO71813.1 - 4.2e-23 81.8 4.7 4.2e-23 81.8 3.2 2.4 2 1 0 2 2 2 1 Mis12-Mtw1 protein family DUF3395 PF11875.3 CDO71813.1 - 0.93 9.1 0.0 0.93 9.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) GMC_oxred_N PF00732.14 CDO71815.1 - 4.7e-57 193.3 0.0 1.1e-56 192.1 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO71815.1 - 8.1e-39 133.1 0.0 1.4e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 CDO71815.1 - 2.5e-05 23.3 0.1 4e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 CDO71815.1 - 4.9e-05 23.2 0.3 0.00012 21.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO71815.1 - 8e-05 21.6 0.2 0.00017 20.6 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDO71815.1 - 0.00011 21.1 0.0 0.00025 20.0 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CDO71815.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO71815.1 - 0.11 10.9 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Semialdhyde_dh PF01118.19 CDO71815.1 - 0.14 12.4 0.2 28 5.0 0.0 3.5 4 0 0 4 4 4 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CDO71815.1 - 0.15 12.5 0.1 0.53 10.7 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.19 CDO71816.1 - 8.2e-13 48.2 1.1 9.6e-13 47.9 0.2 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CDO71816.1 - 1.7e-07 30.8 0.0 3.1e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CDO71816.1 - 1.8e-07 31.2 2.2 5.4e-07 29.6 1.4 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDO71816.1 - 5.7e-05 23.2 0.0 8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CDO71816.1 - 0.00012 21.8 0.4 0.00019 21.2 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CDO71816.1 - 0.00049 20.0 0.0 0.00067 19.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CDO71816.1 - 0.012 15.4 0.1 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldose_epim PF01263.15 CDO71819.1 - 2.4e-14 53.1 0.0 2.3e-07 30.2 0.0 2.7 2 1 0 2 2 2 2 Aldose 1-epimerase ADH_zinc_N PF00107.21 CDO71820.1 - 9.4e-17 60.7 0.0 1.4e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO71820.1 - 8.2e-05 22.3 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CDO71820.1 - 0.00083 20.2 0.0 0.0012 19.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CDO71821.1 - 2.3e-15 56.2 0.1 7.2e-15 54.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO71821.1 - 2.7e-11 43.1 0.0 4.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CDO71821.1 - 0.00046 21.0 0.0 0.00087 20.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CDO71822.1 - 5.2e-14 51.9 0.0 9.8e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO71822.1 - 3.6e-11 42.7 0.0 7.8e-11 41.7 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CDO71822.1 - 0.0014 19.5 0.0 0.0027 18.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CDO71823.1 - 6.8e-11 42.5 0.1 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CDO71823.1 - 2.9e-08 33.2 0.0 4.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CDO71823.1 - 7.3e-08 32.1 0.2 0.0019 17.6 0.0 3.2 4 0 0 4 4 4 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CDO71823.1 - 1.7e-06 28.3 0.0 3.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 CDO71823.1 - 0.00016 20.6 0.0 0.00042 19.3 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Shikimate_DH PF01488.15 CDO71823.1 - 0.0007 19.7 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CDO71823.1 - 0.00089 19.6 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 CDO71823.1 - 0.059 12.0 0.0 0.099 11.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 CDO71823.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus XFP_N PF09364.5 CDO71824.1 - 1.9e-155 517.1 0.0 2.4e-155 516.7 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 CDO71824.1 - 1.7e-67 226.8 0.0 2.9e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 CDO71824.1 - 3.2e-67 225.5 0.0 4.8e-67 224.9 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 CDO71824.1 - 0.012 15.2 0.1 0.034 13.7 0.1 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Acetate_kinase PF00871.12 CDO71825.1 - 9.2e-93 310.8 0.1 2.2e-92 309.6 0.0 1.6 1 1 0 1 1 1 1 Acetokinase family Abhydrolase_6 PF12697.2 CDO71826.1 - 4.8e-18 65.8 0.3 1.6e-16 60.8 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO71826.1 - 2.7e-09 36.9 0.0 5.2e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO71826.1 - 2.7e-05 23.8 0.1 0.0001 21.9 0.0 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CDO71826.1 - 6.2e-05 22.7 0.0 0.00017 21.3 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 CDO71826.1 - 0.005 16.3 0.1 0.91 8.9 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Cpn60_TCP1 PF00118.19 CDO71827.1 - 2e-145 485.1 0.3 2.3e-145 484.9 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AP_endonuc_2 PF01261.19 CDO71827.1 - 0.11 11.7 0.1 0.51 9.5 0.0 2.1 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel Fra10Ac1 PF09725.4 CDO71828.1 - 2.7e-41 140.3 0.3 4.3e-41 139.7 0.2 1.3 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 zf-C4_Topoisom PF01396.14 CDO71828.1 - 0.15 11.5 1.4 0.34 10.4 0.9 1.5 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger FAM176 PF14851.1 CDO71828.1 - 0.34 10.5 1.7 0.38 10.4 0.4 1.6 1 1 1 2 2 2 0 FAM176 family UPF0542 PF15086.1 CDO71828.1 - 5 6.9 5.4 2.6 7.8 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Methyltransf_28 PF02636.12 CDO71829.1 - 2.8e-49 167.8 0.0 3.6e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase eIF-6 PF01912.13 CDO71830.1 - 1.5e-85 285.3 0.2 2e-85 284.8 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family PTPlike_phytase PF14566.1 CDO71831.1 - 5.4e-98 325.0 0.0 7.6e-41 139.6 0.0 3.9 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 CDO71831.1 - 7.2e-05 22.3 0.0 0.024 14.2 0.0 3.1 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDO71831.1 - 0.017 14.4 0.0 0.46 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein-tyrosine phosphatase CDKN3 PF05706.7 CDO71831.1 - 0.023 14.1 0.0 0.063 12.7 0.0 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Mid2 PF04478.7 CDO71832.1 - 0.043 13.2 0.1 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF647 PF04884.9 CDO71835.1 - 8.5e-42 143.0 1.2 1.1e-41 142.6 0.9 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Acyl_transf_1 PF00698.16 CDO71836.1 - 1.3e-66 225.0 2.9 1.3e-64 218.5 0.0 4.2 5 0 0 5 5 5 1 Acyl transferase domain MaoC_dehydratas PF01575.14 CDO71836.1 - 4.1e-30 103.7 0.0 2.5e-29 101.1 0.0 2.4 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 CDO71836.1 - 1.6e-28 98.2 1.0 4.4e-28 96.8 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) ketoacyl-synt PF00109.21 CDO71836.1 - 4.5e-26 91.8 0.3 1.1e-25 90.5 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 CDO71836.1 - 1.3e-19 70.9 0.0 3.7e-19 69.4 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 CDO71836.1 - 5.4e-16 58.4 0.0 2.3e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 CDO71836.1 - 8.1e-15 54.7 0.1 2.1e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain MaoC_dehydrat_N PF13452.1 CDO71836.1 - 2.5e-13 49.9 0.0 3.5e-12 46.2 0.0 2.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase adh_short PF00106.20 CDO71836.1 - 7.3e-07 29.2 0.0 0.0018 18.2 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase Thiolase_N PF00108.18 CDO71836.1 - 0.015 14.2 0.0 0.038 12.9 0.0 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain CTP_transf_2 PF01467.21 CDO71837.1 - 0.022 14.8 0.0 3.2 7.7 0.0 2.6 2 0 0 2 2 2 0 Cytidylyltransferase DEAD PF00270.24 CDO71839.1 - 2.3e-29 102.0 0.1 9.6e-29 100.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO71839.1 - 7e-25 86.7 0.2 1.8e-24 85.3 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CDO71839.1 - 0.011 15.9 0.0 0.078 13.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF202 PF02656.10 CDO71841.1 - 0.068 13.3 4.1 0.42 10.8 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF202) CoA_binding_3 PF13727.1 CDO71841.1 - 0.089 12.6 0.3 0.16 11.8 0.1 1.4 1 1 0 1 1 1 0 CoA-binding domain DnaJ PF00226.26 CDO71842.1 - 3.2e-28 97.2 1.9 5e-28 96.6 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CDO71842.1 - 9.2e-20 70.3 8.7 9.8e-19 67.0 0.4 2.6 3 0 0 3 3 3 2 DnaJ C terminal domain Kelch_4 PF13418.1 CDO71843.1 - 3.4e-28 97.1 10.0 3.2e-10 39.6 0.1 6.0 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CDO71843.1 - 9.9e-22 76.5 19.3 2e-05 24.5 0.0 7.5 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CDO71843.1 - 2.5e-17 62.3 5.9 0.0013 18.6 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 CDO71843.1 - 3.3e-14 52.3 6.5 2.7e-06 27.3 0.1 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CDO71843.1 - 4.3e-13 48.4 0.6 0.0057 16.3 0.0 5.1 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 CDO71843.1 - 1.4e-10 40.5 0.1 0.00032 20.1 0.0 4.5 4 0 0 4 4 4 2 Kelch motif SKG6 PF08693.5 CDO71843.1 - 0.21 10.9 1.4 0.57 9.5 1.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Transposase_21 PF02992.9 CDO71844.1 - 4.7e-35 120.7 0.0 8e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO71844.1 - 6.8e-08 32.0 0.0 6.8e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) DUF3137 PF11335.3 CDO71844.1 - 0.019 14.6 0.1 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) DivIC PF04977.10 CDO71845.1 - 0.016 14.6 3.2 0.016 14.6 2.2 2.4 3 0 0 3 3 3 0 Septum formation initiator ACBP PF00887.14 CDO71846.1 - 3.9e-33 112.9 0.4 5.4e-33 112.5 0.2 1.3 1 1 0 1 1 1 1 Acyl CoA binding protein OmpH PF03938.9 CDO71846.1 - 0.13 12.2 1.0 0.12 12.2 0.7 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PH PF00169.24 CDO71847.1 - 2.5e-26 91.9 0.2 2.1e-19 69.6 0.2 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 CDO71847.1 - 3.3e-13 49.8 3.1 6.1e-10 39.3 2.2 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 CDO71847.1 - 2.7e-09 36.8 0.3 2.3e-06 27.4 0.3 2.8 2 1 0 2 2 2 2 PH domain PH_8 PF15409.1 CDO71847.1 - 2.2e-06 27.6 0.4 4.8e-06 26.5 0.2 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 CDO71847.1 - 8.3e-05 22.4 1.5 0.51 10.2 0.0 2.6 2 1 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 CDO71847.1 - 0.0002 21.4 0.5 0.04 14.0 0.6 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.1 CDO71847.1 - 0.024 14.1 0.0 0.31 10.5 0.0 2.5 2 1 1 3 3 3 0 Pleckstrin homology domain Zn_clus PF00172.13 CDO71848.1 - 1.7e-05 24.6 7.2 2.9e-05 23.8 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 CDO71849.1 - 4.2e-47 160.5 0.0 6.3e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 CDO71850.1 - 7.7e-36 123.4 0.0 1.6e-35 122.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.26 CDO71851.1 - 1.2e-14 53.7 1.2 3.8e-14 52.1 0.8 1.9 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CDO71851.1 - 0.0002 21.1 0.0 0.0048 16.7 0.0 2.6 3 0 0 3 3 3 1 DnaJ C terminal domain NAD_binding_10 PF13460.1 CDO71852.1 - 1.2e-05 25.4 0.7 3.5e-05 23.8 0.5 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CDO71852.1 - 1.9e-05 24.2 0.0 0.00037 20.0 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CDO71852.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family BLVR PF06375.6 CDO71853.1 - 0.052 13.3 6.5 0.1 12.4 4.5 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DDE_3 PF13358.1 CDO71854.1 - 7.5e-34 116.5 0.0 9.6e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO71854.1 - 9.5e-06 25.7 0.0 3.4e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain Fungal_trans PF04082.13 CDO71855.1 - 2.1e-15 56.3 0.1 4.4e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CDO71855.1 - 1.6e-07 31.1 16.4 2.8e-07 30.3 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlxA PF14282.1 CDO71855.1 - 0.0053 16.6 0.4 0.0053 16.6 0.2 1.9 2 0 0 2 2 2 1 FlxA-like protein ADK PF00406.17 CDO71856.1 - 1.1e-57 194.1 0.0 1.5e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CDO71856.1 - 2.9e-15 55.6 0.0 5.6e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CDO71856.1 - 0.00041 21.1 0.0 0.00072 20.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDO71856.1 - 0.0013 18.6 0.0 0.0025 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDO71856.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CDO71856.1 - 0.077 13.3 0.0 0.25 11.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CDO71856.1 - 0.13 11.4 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Cerato-platanin PF07249.7 CDO71857.1 - 1.5e-53 179.8 2.8 1.7e-53 179.7 1.9 1.0 1 0 0 1 1 1 1 Cerato-platanin DDOST_48kD PF03345.9 CDO71858.1 - 3.3e-108 361.9 0.0 3.7e-108 361.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DDE_1 PF03184.14 CDO71859.1 - 2.5e-25 88.8 0.0 4.2e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 CDO71859.1 - 2.1e-06 27.5 3.2 3.9e-06 26.6 0.2 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_psq PF05225.11 CDO71859.1 - 0.00061 19.2 0.1 0.0015 18.0 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 CDO71859.1 - 0.0009 19.0 0.0 0.0027 17.4 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain NmrA PF05368.8 CDO71860.1 - 1.4e-19 70.2 0.0 1.9e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CDO71860.1 - 1.7e-10 41.2 0.1 3e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CDO71860.1 - 1.1e-08 35.3 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CDO71860.1 - 2.6e-06 26.6 0.0 3.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 CDO71860.1 - 0.00025 20.9 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 CDO71860.1 - 0.00029 21.3 0.0 0.00054 20.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 3Beta_HSD PF01073.14 CDO71860.1 - 0.0035 16.1 0.0 0.0053 15.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CDO71860.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.12 CDO71860.1 - 0.049 14.0 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Terpene_synth_C PF03936.11 CDO71861.1 - 2.1e-16 59.9 0.0 2.9e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 CDO71862.1 - 6.3e-70 235.9 0.0 7.1e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RsbRD_N PF14361.1 CDO71862.1 - 0.05 14.0 0.2 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain NmrA PF05368.8 CDO71863.1 - 3.6e-19 68.9 0.4 5.1e-19 68.4 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CDO71863.1 - 4.1e-10 39.9 0.5 6.3e-10 39.3 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CDO71863.1 - 6.6e-06 26.4 0.5 1.5e-05 25.2 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CDO71863.1 - 0.00043 20.2 0.5 0.00094 19.0 0.1 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 CDO71863.1 - 0.00079 19.3 0.3 0.0018 18.2 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 CDO71863.1 - 0.0013 17.7 0.2 0.002 17.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 CDO71863.1 - 0.0046 15.6 0.1 0.0083 14.8 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CDO71863.1 - 0.0084 15.5 0.1 0.039 13.3 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 CDO71863.1 - 0.014 15.8 0.4 0.17 12.3 0.1 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DXP_reductoisom PF02670.11 CDO71863.1 - 0.035 14.6 0.1 0.07 13.6 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase EutN_CcmL PF03319.8 CDO71863.1 - 0.083 13.2 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome FMN_bind PF04205.9 CDO71863.1 - 0.26 11.4 1.7 4.2 7.5 0.1 2.9 2 1 0 2 2 2 0 FMN-binding domain ABC2_membrane PF01061.19 CDO71864.1 - 6.6e-37 126.7 16.0 6.6e-37 126.7 11.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CDO71864.1 - 1.5e-25 90.0 0.0 4.3e-25 88.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.2 CDO71864.1 - 1.8e-05 23.9 23.0 1.8e-05 23.9 16.0 2.0 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 CDO71864.1 - 0.00019 21.4 0.1 0.12 12.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CDO71864.1 - 0.0002 20.5 1.0 0.00095 18.3 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CDO71864.1 - 0.00027 20.3 0.2 0.0037 16.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 CDO71864.1 - 0.0067 16.1 0.2 0.011 15.4 0.2 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CDO71864.1 - 0.0069 16.5 0.1 0.021 14.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDO71864.1 - 0.0081 16.1 0.3 0.023 14.7 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 CDO71864.1 - 0.0092 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 CDO71864.1 - 0.0097 15.7 0.1 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CDO71864.1 - 0.011 15.6 0.2 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CDO71864.1 - 0.015 16.1 0.1 0.034 14.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 CDO71864.1 - 0.019 14.5 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 CDO71864.1 - 0.037 13.4 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 CDO71864.1 - 0.048 13.9 1.1 0.1 12.9 0.2 1.8 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 CDO71864.1 - 0.068 13.3 0.1 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CDO71864.1 - 0.073 12.8 1.6 0.22 11.3 0.4 2.1 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 CDO71864.1 - 0.079 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 CDO71864.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CDO71864.1 - 0.14 11.8 0.9 0.46 10.1 0.4 1.9 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 CDO71864.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CDO71864.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CDO71864.1 - 0.17 11.5 0.1 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 CDO71864.1 - 0.25 10.8 0.0 0.46 10.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CDO71864.1 - 0.27 9.8 0.0 0.41 9.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein HsbA PF12296.3 CDO71865.1 - 6.8e-05 22.7 4.0 6.8e-05 22.7 2.7 2.7 2 1 0 2 2 2 1 Hydrophobic surface binding protein A HsbA PF12296.3 CDO71866.1 - 1.2e-06 28.3 4.1 1.2e-06 28.3 2.9 2.3 1 1 1 2 2 2 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.7 CDO71866.1 - 0.0039 17.0 4.1 0.44 10.3 0.5 2.7 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus HCV_core PF01542.13 CDO71866.1 - 0.018 15.4 1.1 2.8 8.4 0.1 2.9 2 1 1 3 3 3 0 Hepatitis C virus core protein DUF1993 PF09351.5 CDO71866.1 - 0.034 14.0 0.3 0.1 12.5 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) DUF3526 PF12040.3 CDO71867.1 - 0.067 13.3 0.4 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) CheY-binding PF09078.6 CDO71867.1 - 0.07 13.1 0.3 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 CheY binding FANCI_S4 PF14678.1 CDO71867.1 - 0.21 10.6 0.7 0.26 10.3 0.5 1.2 1 0 0 1 1 1 0 FANCI solenoid 4 Pkinase PF00069.20 CDO71868.1 - 3.2e-49 167.4 0.0 3.6e-47 160.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71868.1 - 4.7e-26 91.4 0.0 3.3e-25 88.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CDO71868.1 - 0.00025 20.1 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CDO71868.1 - 0.00082 18.4 0.0 0.0056 15.6 0.0 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CDO71868.1 - 0.015 15.0 3.1 0.041 13.6 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 CDO71868.1 - 0.2 10.9 0.1 0.54 9.5 0.0 1.7 2 0 0 2 2 2 0 RIO1 family DOPA_dioxygen PF08883.6 CDO71870.1 - 5.2e-18 65.0 0.0 8e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Pribosyltran_N PF13793.1 CDO71871.1 - 6.1e-50 167.8 0.2 1.2e-46 157.2 0.0 2.7 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CDO71871.1 - 3.4e-41 140.9 1.0 1.6e-36 125.8 0.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CDO71871.1 - 5.7e-15 55.1 0.3 5e-14 52.0 0.2 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CDO71871.1 - 9.3e-05 21.7 0.1 0.00016 20.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AA_kinase PF00696.23 CDO71872.1 - 2e-36 125.7 2.4 2.7e-36 125.3 1.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CDO71872.1 - 8.7e-11 41.4 0.0 0.00023 20.8 0.0 2.6 2 0 0 2 2 2 2 PUA domain HIT PF01230.18 CDO71873.1 - 8.5e-10 39.0 0.3 1.1e-09 38.6 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CDO71873.1 - 0.0098 16.1 0.2 0.013 15.7 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Per1 PF04080.8 CDO71874.1 - 2.6e-84 282.8 8.6 3e-84 282.5 6.0 1.0 1 0 0 1 1 1 1 Per1-like SID-1_RNA_chan PF13965.1 CDO71874.1 - 0.59 8.2 8.2 0.039 12.1 1.1 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Hist_deacetyl PF00850.14 CDO71875.1 - 3.1e-77 259.9 0.2 3.8e-77 259.6 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MgtE PF01769.11 CDO71876.1 - 3.8e-18 66.0 22.4 8.2e-08 32.6 5.3 3.8 4 0 0 4 4 4 3 Divalent cation transporter DUF1129 PF06570.6 CDO71876.1 - 0.018 14.3 0.1 0.018 14.3 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Ada3 PF10198.4 CDO71877.1 - 1e-23 83.5 0.1 1e-23 83.5 0.0 2.4 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 RNA_polI_A34 PF08208.6 CDO71878.1 - 1e-14 54.6 1.1 1e-14 54.6 0.7 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF1691 PF07950.6 CDO71879.1 - 4.7e-07 29.7 2.1 2.1e-06 27.6 1.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1691) DUF2975 PF11188.3 CDO71879.1 - 0.034 13.8 0.3 0.27 10.9 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) HMG_box PF00505.14 CDO71880.1 - 8.5e-14 51.5 0.7 1.5e-13 50.7 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO71880.1 - 0.00023 21.4 0.4 0.00048 20.4 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain HemY_N PF07219.8 CDO71881.1 - 0.024 14.2 0.1 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 HemY protein N-terminus Sensor PF13796.1 CDO71881.1 - 0.03 13.9 0.9 0.05 13.1 0.6 1.4 1 0 0 1 1 1 0 Putative sensor RSN1_TM PF13967.1 CDO71881.1 - 0.043 13.3 0.1 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport RskA PF10099.4 CDO71881.1 - 0.062 13.0 1.1 0.17 11.5 0.8 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA ADH_N PF08240.7 CDO71882.1 - 7.2e-29 99.7 2.8 1.5e-28 98.6 2.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO71882.1 - 1.5e-16 60.1 0.0 2.5e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO71882.1 - 5.1e-07 30.6 0.0 7.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CDO71882.1 - 8.4e-05 21.7 0.2 0.00014 21.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CDO71882.1 - 0.0013 18.3 0.1 0.0025 17.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 CDO71882.1 - 0.0043 16.9 0.0 0.0064 16.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CDO71882.1 - 0.048 13.7 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 CDO71882.1 - 0.084 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA E1-E2_ATPase PF00122.15 CDO71883.1 - 2.3e-62 210.0 2.0 6e-62 208.6 1.4 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CDO71883.1 - 1.9e-25 90.5 0.0 3.7e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 CDO71883.1 - 4.4e-25 88.2 11.5 1.3e-18 67.2 0.5 4.0 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 CDO71883.1 - 7e-21 73.9 0.0 1.6e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CDO71883.1 - 2.8e-16 58.7 0.0 7.5e-16 57.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CDO71883.1 - 2.3e-11 44.2 0.0 5.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDO71883.1 - 0.00017 21.2 0.5 0.026 14.0 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Tetraspannin PF00335.15 CDO71883.1 - 2.3 7.4 6.8 5.7 6.1 0.1 3.1 3 0 0 3 3 3 0 Tetraspanin family Cerato-platanin PF07249.7 CDO71884.1 - 5.7e-15 55.3 0.1 8.7e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 Cerato-platanin CBM_21 PF03370.8 CDO71885.1 - 4.7e-29 100.6 0.0 8.3e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Glyoxalase_3 PF13468.1 CDO71886.1 - 9.7e-28 97.2 0.2 5.7e-27 94.7 0.1 1.9 1 1 1 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CDO71886.1 - 0.029 14.3 0.0 1 9.4 0.0 2.4 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily IBR PF01485.16 CDO71887.1 - 4.3e-15 55.3 18.6 4.4e-10 39.2 7.1 4.1 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 CDO71887.1 - 0.00012 22.0 12.1 0.00012 22.0 8.4 4.1 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDO71887.1 - 0.00025 20.7 4.3 0.00025 20.7 3.0 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CDO71887.1 - 0.0021 17.6 5.0 0.0021 17.6 3.5 4.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) DUF2746 PF10874.3 CDO71887.1 - 0.0075 16.4 0.0 0.71 10.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2746) zf-RING_5 PF14634.1 CDO71887.1 - 3.6 7.3 39.7 0.02 14.6 7.1 3.8 3 1 0 3 3 3 0 zinc-RING finger domain WD40 PF00400.27 CDO71888.1 - 1.9e-59 195.5 19.8 1.3e-10 40.7 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CDO71888.1 - 1.5e-07 31.3 1.1 0.0014 18.3 0.0 2.9 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CDO71888.1 - 0.00045 19.1 0.4 2.7 6.6 0.0 3.7 1 1 1 3 3 3 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 CDO71888.1 - 0.00059 18.7 0.0 0.00083 18.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Apc4_WD40 PF12894.2 CDO71888.1 - 0.0013 18.1 0.0 0.56 9.7 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Det1 PF09737.4 CDO71888.1 - 0.019 13.7 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 YmzC PF14157.1 CDO71888.1 - 0.022 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 YmzC-like protein Nbas_N PF15492.1 CDO71888.1 - 0.026 13.6 0.5 7.5 5.5 0.0 3.5 2 2 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 CDO71888.1 - 0.027 12.2 0.0 0.047 11.5 0.0 1.3 1 0 0 1 1 1 0 IKI3 family DUF3312 PF11768.3 CDO71888.1 - 0.31 9.1 0.0 1.2 7.2 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3312) Glycos_transf_1 PF00534.15 CDO71889.1 - 5.4e-21 74.7 0.0 2.4e-19 69.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CDO71889.1 - 2.9e-06 27.4 0.0 6.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CDO71889.1 - 2.1e-05 24.6 0.0 0.00024 21.2 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferases group 1 DUF3323 PF11796.3 CDO71889.1 - 0.013 14.8 0.5 0.026 13.8 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) OPT PF03169.10 CDO71891.1 - 1.5e-136 456.3 48.0 4.7e-126 421.7 27.3 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Calcipressin PF04847.7 CDO71892.1 - 5.9e-34 117.2 0.0 7.8e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.17 CDO71892.1 - 0.075 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO71892.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1014 PF06244.7 CDO71893.1 - 1.2e-25 90.1 14.9 1.1e-24 86.9 10.3 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF4632 PF15451.1 CDO71895.1 - 2.3 8.1 4.8 30 4.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) Cerato-platanin PF07249.7 CDO71896.1 - 4.1e-46 155.8 1.9 4.8e-46 155.6 1.3 1.0 1 0 0 1 1 1 1 Cerato-platanin VSP PF03302.8 CDO71899.1 - 2.3e-05 23.2 23.4 2.3e-05 23.2 16.2 4.6 2 1 3 5 5 5 2 Giardia variant-specific surface protein DUF4381 PF14316.1 CDO71899.1 - 0.14 12.2 2.7 0.28 11.2 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Methyltransf_23 PF13489.1 CDO71901.1 - 6.2e-20 71.5 0.0 1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO71901.1 - 2e-17 63.1 0.0 2.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO71901.1 - 2.9e-15 56.5 0.0 1.2e-14 54.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO71901.1 - 1.7e-12 47.9 0.0 2.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO71901.1 - 2.9e-12 46.6 0.0 6.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO71901.1 - 9.2e-12 45.3 0.0 2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDO71901.1 - 9.4e-10 37.9 0.0 1.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CDO71901.1 - 2.5e-09 37.4 0.0 5.3e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CDO71901.1 - 4.4e-07 29.3 0.0 5.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CDO71901.1 - 5.1e-06 25.9 0.0 8.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 CDO71901.1 - 0.0004 20.4 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase FmrO PF07091.6 CDO71901.1 - 0.00054 19.0 0.0 0.00077 18.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) tRNA_U5-meth_tr PF05958.6 CDO71901.1 - 0.0016 17.2 0.0 0.0032 16.2 0.0 1.5 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase PCMT PF01135.14 CDO71901.1 - 0.013 14.9 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.6 CDO71901.1 - 0.017 14.5 0.0 0.04 13.3 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 CDO71901.1 - 0.03 14.0 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 CDO71901.1 - 0.091 13.5 0.0 0.39 11.5 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 CDO71901.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 CDO71902.1 - 4.9e-19 68.6 0.0 6.5e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO71902.1 - 1.2e-15 57.4 0.0 1.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO71902.1 - 1.8e-14 54.0 0.0 3.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO71902.1 - 3e-12 46.8 0.0 5.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO71902.1 - 9e-11 42.3 0.0 1.5e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO71902.1 - 2.2e-09 37.5 0.1 4.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO71902.1 - 6.7e-09 35.8 0.1 1.4e-08 34.7 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 CDO71902.1 - 2.6e-06 26.9 0.0 4.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 CDO71902.1 - 1.3e-05 25.2 0.0 1.7e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 CDO71902.1 - 1.6e-05 24.2 0.0 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 CDO71902.1 - 2.5e-05 23.5 0.0 3.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 CDO71902.1 - 0.0064 16.1 0.0 0.0079 15.8 0.0 1.3 1 1 0 1 1 1 1 Hypothetical methyltransferase Pox_MCEL PF03291.11 CDO71902.1 - 0.008 15.0 0.0 0.27 10.0 0.0 2.0 1 1 0 1 1 1 1 mRNA capping enzyme MetW PF07021.7 CDO71902.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 CDO71902.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CDO71902.1 - 0.02 13.6 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NodS PF05401.6 CDO71902.1 - 0.026 13.8 0.0 0.07 12.5 0.0 1.6 1 1 0 1 1 1 0 Nodulation protein S (NodS) FmrO PF07091.6 CDO71902.1 - 0.045 12.7 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TPMT PF05724.6 CDO71902.1 - 0.072 12.5 0.2 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_24 PF13578.1 CDO71902.1 - 0.083 13.7 0.1 0.24 12.2 0.0 1.8 3 0 0 3 3 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CDO71902.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CmcI PF04989.7 CDO71902.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Cephalosporin hydroxylase PCEMA1 PF07418.6 CDO71903.1 - 0.042 13.2 10.4 0.075 12.3 7.2 1.3 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Nop14 PF04147.7 CDO71903.1 - 0.69 7.7 21.9 0.96 7.2 15.2 1.2 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 CDO71903.1 - 5.2 6.5 14.6 18 4.7 10.1 1.9 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.10 CDO71903.1 - 5.4 5.5 6.4 8 4.9 4.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.6 CDO71903.1 - 6.9 6.1 21.6 15 5.0 15.0 1.5 1 0 0 1 1 1 0 PPP4R2 Ras PF00071.17 CDO71904.1 - 2.6e-62 208.9 0.6 3e-62 208.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO71904.1 - 3.9e-19 69.3 0.1 6e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO71904.1 - 2.8e-16 59.2 0.1 3.5e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO71904.1 - 4.9e-06 25.8 0.1 5.8e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDO71904.1 - 9.4e-06 25.1 0.3 2.1e-05 24.0 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDO71904.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CDO71904.1 - 0.00057 19.1 0.1 0.001 18.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 CDO71904.1 - 0.00087 19.4 0.2 0.056 13.6 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 CDO71904.1 - 0.0015 17.7 0.0 0.0072 15.6 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 CDO71904.1 - 0.0069 16.3 0.0 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CDO71904.1 - 0.0085 16.2 0.0 0.019 15.1 0.0 1.6 1 1 1 2 2 2 1 AAA domain SPATA19 PF15212.1 CDO71904.1 - 0.032 14.2 0.2 0.057 13.4 0.1 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial DUF258 PF03193.11 CDO71904.1 - 0.037 13.2 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CDO71904.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain BRCA-2_OB3 PF09104.5 CDO71904.1 - 0.053 13.3 0.1 0.077 12.8 0.0 1.1 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 AAA_5 PF07728.9 CDO71904.1 - 0.058 13.1 0.0 0.091 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IMS PF00817.15 CDO71905.1 - 5.8e-42 142.9 0.2 1.4e-41 141.7 0.1 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 CDO71905.1 - 4.1e-13 49.3 0.0 1.2e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.2 CDO71905.1 - 1.5e-05 24.7 0.2 6e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain IMS_HHH PF11798.3 CDO71905.1 - 4.8e-05 23.1 0.0 0.00023 21.0 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif DUF4414 PF14377.1 CDO71905.1 - 8e-05 22.5 0.2 0.34 10.8 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) BRCT PF00533.21 CDO71905.1 - 0.0048 17.0 0.1 0.033 14.3 0.1 2.4 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF1805 PF08827.6 CDO71905.1 - 0.12 12.1 0.0 0.46 10.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) HhH-GPD PF00730.20 CDO71906.1 - 3.2e-21 75.6 0.0 5.5e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CDO71906.1 - 8.4e-09 34.6 0.0 1.7e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 CDO71906.1 - 0.0082 16.2 0.1 0.21 11.7 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 CDO71906.1 - 0.039 14.1 3.5 0.039 14.1 2.4 2.2 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Phos_pyr_kin PF08543.7 CDO71907.1 - 7.3e-52 175.9 0.3 2.5e-50 170.9 0.2 2.2 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CDO71907.1 - 2.7e-43 148.1 0.5 3.5e-43 147.8 0.3 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 CDO71907.1 - 0.00092 18.4 0.4 0.0052 15.9 0.3 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PAP1 PF08601.5 CDO71908.1 - 1.1 8.8 13.2 1.5 8.4 9.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF992 PF06186.6 CDO71909.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF992) PAF-AH_p_II PF03403.8 CDO71911.1 - 1.4e-27 96.0 0.0 2.3e-24 85.4 0.0 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 CDO71911.1 - 6.7e-09 35.6 0.2 1.2e-08 34.7 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO71911.1 - 3.4e-07 30.3 0.1 5.8e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CDO71911.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 CDO71911.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 CDO71911.1 - 0.015 14.4 0.0 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 CDO71911.1 - 0.049 13.2 0.0 0.083 12.5 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 CDO71911.1 - 0.078 12.5 0.3 0.23 10.9 0.1 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Mak10 PF04112.8 CDO71912.1 - 1.3e-32 112.3 0.0 2.3e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-synt_1b PF00579.20 CDO71913.1 - 1.7e-68 230.9 0.0 5.1e-68 229.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) SUV3_C PF12513.3 CDO71915.1 - 2.9e-11 42.6 1.7 2.9e-11 42.6 1.2 2.1 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CDO71915.1 - 4.3e-07 29.7 0.0 1.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MRP-S33 PF08293.6 CDO71916.1 - 9.6e-22 76.7 0.2 1.2e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 EF-hand_4 PF12763.2 CDO71917.1 - 1.8e-17 62.9 0.0 3.3e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CDO71917.1 - 2e-05 24.6 0.0 7.7e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CDO71917.1 - 0.00019 20.5 0.0 0.15 11.4 0.0 2.8 2 0 0 2 2 2 2 EF hand DUF812 PF05667.6 CDO71917.1 - 0.00022 19.9 0.9 0.00042 18.9 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF1720 PF08226.6 CDO71917.1 - 0.00087 19.3 129.2 0.19 11.8 25.6 5.2 1 1 2 3 3 3 2 Domain of unknown function (DUF1720) EF-hand_6 PF13405.1 CDO71917.1 - 0.0055 16.4 0.0 5.1 7.2 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain Syntaxin PF00804.20 CDO71917.1 - 0.022 14.9 4.4 0.076 13.1 3.1 1.9 1 1 0 1 1 1 0 Syntaxin TBPIP PF07106.8 CDO71917.1 - 1 8.8 6.6 1 8.8 3.3 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4407 PF14362.1 CDO71917.1 - 6.5 5.6 8.5 14 4.4 5.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RhoGEF PF00621.15 CDO71918.1 - 1.5e-46 158.5 2.7 2.8e-46 157.6 1.9 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 CDO71918.1 - 3.8e-24 83.8 0.4 5.4e-13 48.1 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CDO71918.1 - 7e-24 83.1 1.2 1.2e-11 43.9 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CDO71918.1 - 3.1e-13 48.9 0.0 8.8e-06 25.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 CDO71918.1 - 4.9e-10 38.6 0.7 1e-09 37.6 0.5 1.6 1 0 0 1 1 1 1 WH2 motif PH PF00169.24 CDO71918.1 - 1.3e-07 31.7 0.0 1.1e-06 28.7 0.0 2.3 2 0 0 2 2 2 1 PH domain OPA3 PF07047.7 CDO71919.1 - 3.5e-34 117.4 1.1 5.4e-34 116.8 0.7 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) COG5 PF10392.4 CDO71919.1 - 0.017 15.0 0.3 0.033 14.1 0.2 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Sec34 PF04136.10 CDO71919.1 - 0.024 14.3 0.3 0.041 13.5 0.2 1.3 1 0 0 1 1 1 0 Sec34-like family FliD_C PF07195.7 CDO71919.1 - 0.024 13.9 0.6 0.036 13.3 0.1 1.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF445 PF04286.7 CDO71919.1 - 0.026 14.0 1.3 0.033 13.7 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HR1 PF02185.11 CDO71919.1 - 0.06 13.0 0.8 0.13 11.9 0.5 1.6 1 0 0 1 1 1 0 Hr1 repeat Acyl-CoA_ox_N PF14749.1 CDO71919.1 - 0.081 13.2 0.2 0.15 12.3 0.2 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal L31 PF09784.4 CDO71919.1 - 0.12 12.4 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 MADF_DNA_bdg PF10545.4 CDO71919.1 - 0.13 12.4 0.7 0.27 11.4 0.5 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Matrilin_ccoil PF10393.4 CDO71919.1 - 0.25 10.7 2.9 0.15 11.4 0.3 1.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin IPK PF03770.11 CDO71920.1 - 1.1e-34 119.8 0.0 4e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase Nucleoplasmin PF03066.10 CDO71920.1 - 1.4 8.4 9.0 0.11 11.9 2.7 1.8 2 0 0 2 2 2 0 Nucleoplasmin Cellulase PF00150.13 CDO71922.1 - 2.1e-07 30.4 0.0 0.00095 18.4 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) p450 PF00067.17 CDO71924.1 - 1.2e-59 202.0 0.0 2.8e-59 200.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF655 PF04919.7 CDO71924.1 - 0.058 13.1 0.2 0.13 11.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF655) p450 PF00067.17 CDO71925.1 - 2.6e-47 161.4 0.0 2.2e-36 125.3 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 Lipase_3 PF01764.20 CDO71926.1 - 1e-07 31.6 0.0 6.6e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CDO71926.1 - 0.067 12.9 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 CDO71926.1 - 0.15 11.7 0.1 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 CDO71926.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Rft-1 PF04506.8 CDO71927.1 - 6.3e-92 308.7 3.2 8.2e-92 308.3 2.2 1.1 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 CDO71927.1 - 7.1e-07 28.7 8.0 7.1e-07 28.7 5.5 2.7 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein MFS_1 PF07690.11 CDO71928.1 - 3.4e-25 88.4 17.4 3.4e-25 88.4 12.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 CDO71928.1 - 0.51 8.3 3.0 0.47 8.4 0.8 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CDC73 PF05179.9 CDO71930.1 - 4.4e-49 167.2 0.2 5.9e-49 166.8 0.1 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family eIF2A PF08662.6 CDO71931.1 - 1e-16 61.2 0.0 2.2e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF3498 PF12004.3 CDO71932.1 - 1 8.4 8.4 1.7 7.6 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Hydrophobin PF01185.13 CDO71933.1 - 7.8e-21 74.3 9.2 9.2e-21 74.0 6.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Tad PF13400.1 CDO71933.1 - 6.7 6.8 8.1 1.1 9.3 0.5 2.3 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Ndc1_Nup PF09531.5 CDO71934.1 - 0.12 10.7 2.1 0.19 10.1 1.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FtsX PF02687.16 CDO71934.1 - 0.45 10.2 4.5 0.28 10.9 0.3 2.3 2 1 0 2 2 2 0 FtsX-like permease family Peptidase_U4 PF03419.8 CDO71934.1 - 0.67 8.9 2.9 0.31 10.0 0.5 1.5 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Myb_DNA-bind_2 PF08914.6 CDO71935.1 - 2.7e-16 59.0 8.8 6e-08 32.3 1.1 2.7 2 0 0 2 2 2 2 Rap1 Myb domain Rap1-DNA-bind PF09197.5 CDO71935.1 - 0.00031 21.2 10.7 0.06 13.9 0.4 3.1 1 1 1 2 2 2 2 Rap1, DNA-binding Glyco_hydro_31 PF01055.21 CDO71936.1 - 7.5e-161 535.8 1.2 9.4e-161 535.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CDO71936.1 - 2.6e-11 43.1 0.9 1.1e-10 41.2 0.6 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Shugoshin_C PF07557.6 CDO71939.1 - 3.5e-09 35.9 2.9 3.5e-09 35.9 2.0 4.0 4 0 0 4 4 4 1 Shugoshin C terminus Shugoshin_N PF07558.6 CDO71939.1 - 1.5e-06 27.7 3.0 3.2e-06 26.7 2.1 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region SnAC PF14619.1 CDO71939.1 - 0.25 11.5 0.0 0.25 11.5 0.0 3.8 3 1 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex Pkinase PF00069.20 CDO71940.1 - 4.9e-50 170.0 0.0 7.3e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71940.1 - 7e-24 84.2 0.0 2e-23 82.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 CDO71940.1 - 0.032 13.5 0.5 2.8 7.2 0.3 2.3 1 1 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 CDO71940.1 - 0.039 12.7 0.1 0.059 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 CDO71940.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Cyclase PF04199.8 CDO71941.1 - 2e-15 56.9 0.0 2.8e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cyclase PF04199.8 CDO71942.1 - 4.1e-08 33.0 0.0 6.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase MFS_1 PF07690.11 CDO71943.1 - 6.7e-32 110.5 36.7 1.3e-18 66.9 17.3 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Hydrophobin PF01185.13 CDO71944.1 - 3e-22 78.8 8.4 4e-22 78.4 5.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Nop14 PF04147.7 CDO71946.1 - 0.0012 16.8 2.2 0.0015 16.5 1.5 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 CDO71946.1 - 2.4 6.0 4.5 3.1 5.7 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Hydrophobin PF01185.13 CDO71947.1 - 5.9e-20 71.5 9.2 7.4e-20 71.1 6.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Pantoate_transf PF02548.10 CDO71947.1 - 0.051 12.7 0.5 0.056 12.5 0.4 1.1 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Pkinase PF00069.20 CDO71948.1 - 8e-29 100.5 0.0 1.1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO71948.1 - 3.9e-16 58.9 0.0 6.5e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO71948.1 - 2.6e-05 23.3 0.0 4.9e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CDO71948.1 - 0.0012 18.5 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RVT_2 PF07727.9 CDO71949.1 - 6.3e-82 274.2 0.0 8.7e-82 273.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4218 PF13960.1 CDO71949.1 - 1.4e-05 24.5 0.0 3.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDE_3 PF13358.1 CDO71950.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO71950.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DUF4419 PF14388.1 CDO71951.1 - 7.5e-55 186.2 0.0 1.2e-42 146.2 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) COesterase PF00135.23 CDO71952.1 - 5.5e-84 282.7 0.0 8e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CDO71952.1 - 3.2e-11 43.2 0.1 5.7e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDO71952.1 - 1.8e-05 24.1 0.6 3e-05 23.3 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDO71952.1 - 0.012 15.4 0.1 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.17 CDO71953.1 - 1.4e-121 406.2 0.0 5.6e-61 206.4 0.0 2.7 2 2 0 2 2 2 2 Cytochrome P450 DUF667 PF05018.8 CDO71953.1 - 0.0031 16.7 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF667) Prefoldin_2 PF01920.15 CDO71953.1 - 0.018 14.8 0.6 6.4 6.6 0.0 2.7 2 0 0 2 2 2 0 Prefoldin subunit HTH_16 PF12645.2 CDO71953.1 - 0.036 13.9 0.1 14 5.7 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain Imm20 PF15568.1 CDO71953.1 - 0.1 12.5 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 20 WD40 PF00400.27 CDO71955.1 - 1.3e-13 50.2 4.0 0.00049 19.8 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat DDE_3 PF13358.1 CDO71956.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO71956.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Nucleos_tra2_C PF07662.8 CDO71957.1 - 2.9e-66 222.9 4.2 2.9e-66 222.9 2.9 2.2 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 CDO71957.1 - 1.4e-17 63.7 3.1 1.4e-17 63.7 2.1 4.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 CDO71957.1 - 0.00044 20.1 6.9 0.00044 20.1 4.8 3.4 3 0 0 3 3 3 1 Nucleoside recognition CAAD PF14159.1 CDO71957.1 - 5.2 6.7 11.0 4.5 6.9 0.5 3.3 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Ferritin_2 PF13668.1 CDO71959.1 - 1.7e-33 115.4 0.1 2.5e-33 114.9 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.19 CDO71960.1 - 3.3e-78 263.2 18.1 1.3e-76 258.0 11.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CDO71960.1 - 8.9e-19 67.3 26.3 1.6e-18 66.5 18.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3446 PF11928.3 CDO71963.1 - 0.053 13.7 0.3 4.7 7.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) MPC PF03650.8 CDO71964.1 - 1.8e-39 134.3 0.3 2.3e-39 134.0 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Na_H_Exchanger PF00999.16 CDO71965.1 - 8.8e-46 156.1 23.4 1.2e-45 155.7 16.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Acyl-CoA_dh_M PF02770.14 CDO71966.1 - 3e-05 23.4 0.0 6.9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CDO71966.1 - 0.0056 16.8 1.8 0.034 14.2 0.5 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DEAD PF00270.24 CDO71971.1 - 1.6e-05 24.4 0.0 3.7e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase RVT_1 PF00078.22 CDO71973.1 - 2.3e-35 121.9 0.0 4.1e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlxA PF14282.1 CDO71973.1 - 0.0015 18.4 1.0 0.0032 17.4 0.7 1.5 1 0 0 1 1 1 1 FlxA-like protein RR_TM4-6 PF06459.7 CDO71974.1 - 1.1 9.1 8.5 1.3 8.8 5.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ku_C PF03730.9 CDO71974.1 - 2.5 8.7 8.2 4.3 7.9 5.7 1.3 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Methyltransf_31 PF13847.1 CDO71976.1 - 5.4e-09 35.8 0.0 6.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO71976.1 - 2.1e-08 34.7 0.0 3.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO71976.1 - 7e-08 32.5 0.2 1.5e-07 31.4 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO71976.1 - 2e-07 31.4 0.0 3.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO71976.1 - 4.9e-07 30.1 0.0 8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO71976.1 - 1.7e-06 28.3 0.0 3.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDO71976.1 - 6.8e-06 25.5 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CDO71976.1 - 8e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 CDO71976.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Ubie_methyltran PF01209.13 CDO71976.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 CDO71976.1 - 0.024 15.4 0.0 0.052 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 CDO71976.1 - 0.07 12.7 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.14 CDO71976.1 - 0.15 11.5 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 CDO71978.1 - 1e-08 34.9 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO71978.1 - 1.1e-08 35.6 0.0 1.8e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO71978.1 - 3.8e-08 33.3 0.3 9e-08 32.1 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO71978.1 - 4.4e-08 33.5 0.0 6.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO71978.1 - 3.2e-07 30.7 0.0 4.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDO71978.1 - 8.5e-07 28.5 0.0 1.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CDO71978.1 - 1.1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO71978.1 - 9e-05 22.2 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDO71978.1 - 0.0069 15.5 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 CDO71978.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_24 PF13578.1 CDO71978.1 - 0.012 16.4 0.0 0.025 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 CDO71978.1 - 0.035 13.7 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF43 PF01861.11 CDO71978.1 - 0.063 12.2 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 PCMT PF01135.14 CDO71978.1 - 0.13 11.7 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF788 PF05620.6 CDO71979.1 - 0.049 13.4 3.5 0.041 13.7 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF788) DUF2637 PF10935.3 CDO71979.1 - 0.099 12.5 2.2 0.24 11.3 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2637) DUF3830 PF12903.2 CDO71980.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) DUF788 PF05620.6 CDO71980.1 - 0.17 11.7 5.4 0.4 10.5 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Cation_efflux PF01545.16 CDO71980.1 - 0.49 9.4 9.7 0.62 9.0 6.7 1.1 1 0 0 1 1 1 0 Cation efflux family Solute_trans_a PF03619.11 CDO71983.1 - 2.6e-52 177.8 12.9 3e-52 177.6 8.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PFL PF02901.10 CDO71985.1 - 0.1 11.0 2.5 0.14 10.5 1.7 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase SET PF00856.23 CDO71986.1 - 1.7e-11 44.7 0.0 3.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 SET domain IncA PF04156.9 CDO71987.1 - 0.12 11.9 12.1 0.53 9.8 8.4 1.9 1 1 0 1 1 1 0 IncA protein Phage_GPO PF05929.6 CDO71987.1 - 0.18 11.0 3.6 0.35 10.0 2.5 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIC PF04977.10 CDO71987.1 - 0.36 10.3 12.6 0.13 11.7 1.2 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.1 CDO71987.1 - 1.8 7.4 12.0 1.8 7.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.1 CDO71987.1 - 2.6 7.1 12.5 8.6 5.4 8.6 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 YlqD PF11068.3 CDO71987.1 - 3.2 7.8 13.8 1.5 8.8 7.5 1.9 2 0 0 2 2 2 0 YlqD protein Pox_A_type_inc PF04508.7 CDO71987.1 - 5.6 7.0 11.7 0.14 11.9 0.9 3.1 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat DUF4140 PF13600.1 CDO71987.1 - 6.2 7.3 12.9 4.3 7.8 1.7 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.7 CDO71987.1 - 6.7 7.1 8.5 1.8 8.9 0.3 2.8 2 0 0 2 2 2 0 SlyX HSP70 PF00012.15 CDO71989.1 - 0.09 10.6 0.1 0.31 8.8 0.0 1.8 2 1 0 2 2 2 0 Hsp70 protein Mnd1 PF03962.10 CDO71990.1 - 0.044 13.4 14.3 0.078 12.6 9.9 1.4 1 0 0 1 1 1 0 Mnd1 family Hemagglutinin PF00509.13 CDO71990.1 - 0.056 11.5 0.6 0.081 11.0 0.4 1.2 1 0 0 1 1 1 0 Haemagglutinin Vfa1 PF08432.5 CDO71990.1 - 0.56 10.2 14.1 0.88 9.5 9.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3584 PF12128.3 CDO71990.1 - 0.71 7.1 20.0 0.93 6.7 13.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 CDO71990.1 - 0.74 8.8 16.3 1 8.3 11.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 CDO71990.1 - 1.4 7.2 7.2 2.2 6.6 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 CDO71990.1 - 2 7.9 16.2 3.5 7.1 11.2 1.5 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 CDO71990.1 - 2.3 5.9 9.9 3 5.5 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 CDO71990.1 - 2.8 8.3 12.8 1.4 9.2 1.3 2.5 1 1 1 2 2 2 0 Snapin/Pallidin Tho2 PF11262.3 CDO71990.1 - 8.5 5.3 14.0 7.1 5.5 2.2 2.2 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 RVT_1 PF00078.22 CDO71992.1 - 2.7e-08 33.4 0.0 6.5e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 CDO71992.1 - 1.4e-07 31.5 0.0 9.7e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 CDO71992.1 - 6.3e-07 29.3 0.1 2.3e-06 27.5 0.1 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 CDO71992.1 - 3.2e-06 26.8 0.0 7.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 CDO71992.1 - 5.1e-05 22.9 3.0 0.0001 22.0 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 CDO71992.1 - 0.00024 21.5 0.0 0.00057 20.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.21 CDO71992.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_2 PF13696.1 CDO71992.1 - 0.0054 16.1 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.5 CDO71992.1 - 0.029 13.9 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease DUF4218 PF13960.1 CDO71994.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) RP-C_C PF11800.3 CDO71994.1 - 0.067 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Upf2 PF04050.9 CDO71995.1 - 1.1 9.0 9.7 0.32 10.7 0.4 2.8 3 0 0 3 3 3 0 Up-frameshift suppressor 2 B9-C2 PF07162.6 CDO71996.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein NOA36 PF06524.7 CDO71996.1 - 3.7 6.7 10.3 7.2 5.7 7.1 1.4 1 0 0 1 1 1 0 NOA36 protein ERM PF00769.14 CDO71999.1 - 0.00028 20.4 15.7 0.00043 19.9 10.9 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF3450 PF11932.3 CDO71999.1 - 0.00085 18.6 12.1 0.0015 17.8 8.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.2 CDO71999.1 - 0.00085 19.1 16.3 0.0018 18.0 11.3 1.5 1 0 0 1 1 1 1 Tropomyosin like CALCOCO1 PF07888.6 CDO71999.1 - 0.0097 14.2 15.6 0.013 13.8 10.8 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like APG6 PF04111.7 CDO71999.1 - 0.032 13.2 13.7 0.048 12.7 9.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Sin3_corepress PF08295.7 CDO71999.1 - 0.055 13.2 0.5 0.2 11.4 0.3 2.0 1 0 0 1 1 1 0 Sin3 family co-repressor DUF3584 PF12128.3 CDO71999.1 - 0.079 10.2 22.1 0.01 13.2 9.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) WD40_alt PF14077.1 CDO71999.1 - 0.092 12.3 0.2 2.4 7.8 0.1 3.0 4 0 0 4 4 4 0 Alternative WD40 repeat motif FUSC PF04632.7 CDO71999.1 - 0.16 10.3 11.1 0.25 9.7 7.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family HemY_N PF07219.8 CDO71999.1 - 0.19 11.2 9.8 0.096 12.2 1.7 2.5 2 0 0 2 2 2 0 HemY protein N-terminus CytochromB561_N PF09786.4 CDO71999.1 - 0.34 9.3 4.9 0.47 8.8 3.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Reo_sigmaC PF04582.7 CDO71999.1 - 0.47 9.5 8.3 0.44 9.6 0.8 2.6 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Fmp27_WPPW PF10359.4 CDO71999.1 - 0.62 8.4 11.9 0.98 7.7 8.0 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain V_ATPase_I PF01496.14 CDO71999.1 - 0.8 7.4 9.0 1.1 7.0 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nsp1_C PF05064.8 CDO71999.1 - 1.4 8.5 9.7 0.56 9.8 0.5 2.6 1 1 1 2 2 2 0 Nsp1-like C-terminal region Mnd1 PF03962.10 CDO71999.1 - 1.6 8.3 18.5 0.35 10.5 6.0 2.3 1 1 1 2 2 2 0 Mnd1 family DUF2175 PF09943.4 CDO71999.1 - 2.1 8.4 7.5 0.68 10.0 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) TMPIT PF07851.8 CDO71999.1 - 2.5 7.1 13.2 0.049 12.7 1.9 2.5 2 1 1 3 3 3 0 TMPIT-like protein Spc7 PF08317.6 CDO71999.1 - 3.8 6.0 17.2 0.86 8.2 5.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.7 CDO71999.1 - 6.2 7.2 17.0 4.9 7.5 2.4 3.4 2 1 1 3 3 3 0 SlyX AAA_13 PF13166.1 CDO71999.1 - 9.9 4.4 15.4 6.8 5.0 2.5 1.9 1 1 1 2 2 2 0 AAA domain DUF4448 PF14610.1 CDO72000.1 - 2.7e-08 33.5 0.0 4.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 CDO72000.1 - 1.3e-05 25.5 0.7 2.7e-05 24.5 0.5 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4366 PF14283.1 CDO72000.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TMEMspv1-c74-12 PF11044.3 CDO72000.1 - 0.17 11.4 0.3 0.28 10.7 0.2 1.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PARP PF00644.15 CDO72001.1 - 7e-14 51.7 0.0 1.7e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 CDO72001.1 - 0.001 18.5 0.0 0.0028 17.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Pkinase PF00069.20 CDO72002.1 - 3.1e-11 42.9 0.0 8.4e-10 38.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Peptidase_A4 PF01828.12 CDO72003.1 - 1e-81 273.0 9.4 1.3e-81 272.6 6.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family AP3B1_C PF14796.1 CDO72003.1 - 0.026 14.2 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Bac_chlorC PF02043.12 CDO72004.1 - 8 6.3 7.8 1.8 8.3 1.2 2.0 1 1 1 2 2 2 0 Bacteriochlorophyll C binding protein Ank_2 PF12796.2 CDO72005.1 - 4.1e-34 116.7 0.7 1.6e-10 41.1 0.1 5.8 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 CDO72005.1 - 9.7e-26 88.2 2.7 1.3e-05 24.7 0.0 7.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 CDO72005.1 - 2.4e-23 82.0 0.7 8.4e-06 26.1 0.0 7.2 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDO72005.1 - 5.4e-20 70.9 3.5 0.00027 21.0 0.0 7.4 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO72005.1 - 3.7e-19 66.9 0.0 0.0069 16.5 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat Adipogenin PF15202.1 CDO72006.1 - 0.055 13.3 1.2 1.6 8.6 0.0 3.0 3 0 0 3 3 3 0 Adipogenin HPP PF04982.8 CDO72006.1 - 0.48 10.2 0.1 0.48 10.2 0.0 3.0 3 0 0 3 3 3 0 HPP family DUF3687 PF12459.3 CDO72008.1 - 4.2 6.6 6.7 2.2 7.6 0.8 2.6 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein MotA_ExbB PF01618.11 CDO72008.1 - 5 6.7 5.8 1.9 8.1 0.6 2.3 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family DUF3328 PF11807.3 CDO72009.1 - 9.2e-22 77.7 0.7 1.3e-21 77.3 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 CDO72010.1 - 1e-20 74.3 0.0 1.8e-20 73.5 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DDE_3 PF13358.1 CDO72012.1 - 1.1e-10 41.3 0.0 1.5e-09 37.7 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Terminase_2 PF03592.11 CDO72012.1 - 0.073 13.3 0.1 0.61 10.3 0.0 2.0 2 0 0 2 2 2 0 Terminase small subunit NUDE_C PF04880.8 CDO72012.1 - 4.1 7.7 5.4 6.9 6.9 3.8 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region MFS_1 PF07690.11 CDO72013.1 - 8.8e-38 129.9 52.0 1.5e-36 125.8 36.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO72013.1 - 6.7e-15 54.3 8.1 1.7e-13 49.6 8.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CDO72013.1 - 3.2e-14 52.3 13.5 3.2e-14 52.3 9.4 3.2 1 1 2 3 3 3 1 Sugar (and other) transporter Beta-lactamase PF00144.19 CDO72014.1 - 9.3e-44 149.7 0.2 1.2e-43 149.4 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DDE_3 PF13358.1 CDO72015.1 - 2e-15 56.8 0.5 2.2e-15 56.7 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO72015.1 - 0.0074 16.3 0.0 0.0093 16.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Beta-lactamase PF00144.19 CDO72016.1 - 1.1e-38 133.1 0.7 1.8e-38 132.3 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF1212 PF06738.7 CDO72017.1 - 4e-41 140.6 0.8 4e-41 140.6 0.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CDO72017.1 - 4.5e-18 65.4 4.3 4.5e-18 65.4 3.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) GAGA_bind PF06217.7 CDO72018.1 - 0.00067 19.7 2.0 0.0011 19.0 1.4 1.3 1 0 0 1 1 1 1 GAGA binding protein-like family ATG16 PF08614.6 CDO72018.1 - 0.0011 18.8 6.0 0.0018 18.1 4.2 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF2884 PF11101.3 CDO72018.1 - 0.029 13.7 3.1 0.042 13.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF3552 PF12072.3 CDO72018.1 - 0.048 12.8 12.8 0.079 12.1 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2058 PF09831.4 CDO72018.1 - 0.67 9.8 8.1 1.6 8.5 5.6 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF972 PF06156.8 CDO72018.1 - 1.1 9.6 8.6 0.35 11.2 3.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 CDO72018.1 - 6.1 5.7 8.1 9.8 5.0 5.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2963 PF11178.3 CDO72019.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) Elf1 PF05129.8 CDO72020.1 - 1.1 9.0 3.9 0.26 10.9 0.3 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Clathrin-link PF09268.5 CDO72021.1 - 0.44 9.6 1.8 1 8.4 0.0 2.2 2 0 0 2 2 2 0 Clathrin, heavy-chain linker Asp_protease_2 PF13650.1 CDO72022.1 - 0.0031 17.9 0.0 0.0062 17.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CDO72022.1 - 0.033 13.7 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease HAMP PF00672.20 CDO72025.1 - 5.4e-16 58.5 7.4 4.3e-08 33.2 0.2 4.0 5 0 0 5 5 5 2 HAMP domain Baculo_PEP_C PF04513.7 CDO72025.1 - 0.00098 18.9 5.3 0.3 10.8 0.1 3.0 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Rad50_zn_hook PF04423.9 CDO72025.1 - 0.17 11.3 0.0 0.41 10.1 0.0 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF2365 PF10157.4 CDO72025.1 - 0.68 9.8 4.2 11 5.8 0.0 3.6 3 2 2 5 5 5 0 Uncharacterized conserved protein (DUF2365) VBS PF08913.5 CDO72025.1 - 0.7 10.1 3.9 11 6.3 0.2 3.1 3 0 0 3 3 3 0 Vinculin Binding Site HAMP PF00672.20 CDO72026.1 - 5.8e-32 109.7 14.5 5.4e-09 36.1 0.0 5.2 5 0 0 5 5 5 4 HAMP domain HATPase_c PF02518.21 CDO72026.1 - 9.8e-28 96.1 0.6 2.5e-27 94.7 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CDO72026.1 - 7.2e-27 93.6 0.3 4.6e-24 84.5 0.2 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 CDO72026.1 - 3.5e-16 58.9 0.9 1.4e-15 57.0 0.6 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AcylCoA_dehyd_C PF12186.3 CDO72026.1 - 0.0042 16.9 4.8 14 5.5 0.0 5.0 4 1 1 5 5 5 1 Acyl-CoA dehydrogenase C terminal Pox_A_type_inc PF04508.7 CDO72026.1 - 0.075 12.8 0.0 1.4 8.9 0.0 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.4 CDO72026.1 - 0.76 9.6 3.8 14 5.5 0.6 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2365 PF10157.4 CDO72026.1 - 5 7.0 10.4 11 5.8 0.0 4.8 4 1 2 6 6 6 0 Uncharacterized conserved protein (DUF2365) Peptidase_C13 PF01650.13 CDO72027.1 - 1.5e-43 148.9 0.1 1.9e-43 148.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Pyr_redox_2 PF07992.9 CDO72029.1 - 4.6e-09 36.4 0.0 0.0017 18.2 0.2 4.1 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO72029.1 - 7.9e-09 35.8 0.0 1.8e-07 31.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDO72029.1 - 9.4e-06 25.8 0.1 0.28 11.2 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CDO72029.1 - 0.00022 20.2 2.8 0.89 8.3 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 CDO72029.1 - 0.0085 15.0 0.2 0.11 11.3 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 CDO72029.1 - 0.018 13.9 0.2 5.2 5.8 0.0 2.6 2 1 1 3 3 3 0 Lycopene cyclase protein CbiQ PF02361.11 CDO72030.1 - 0.011 15.3 1.8 0.011 15.3 1.3 1.9 2 0 0 2 2 2 0 Cobalt transport protein MerC PF03203.9 CDO72030.1 - 1 9.7 6.9 2.1 8.7 2.5 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein DUF4131 PF13567.1 CDO72030.1 - 4.1 6.7 6.4 6.5 6.1 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_M20 PF01546.23 CDO72031.1 - 6.5e-08 32.2 0.3 1.3e-07 31.3 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CDO72031.1 - 3.6e-06 26.6 0.0 1.2e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain FSH1 PF03959.8 CDO72032.1 - 3.5e-45 154.0 0.0 1.2e-43 149.0 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 CDO72032.1 - 3.8e-06 26.9 0.5 0.00011 22.1 0.2 2.6 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO72032.1 - 0.00089 19.0 0.1 0.0024 17.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cyd_oper_YbgE PF09600.5 CDO72032.1 - 0.0069 16.5 0.1 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 Cyd operon protein YbgE (Cyd_oper_YbgE) DUF2235 PF09994.4 CDO72032.1 - 0.054 12.8 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_2 PF02230.11 CDO72032.1 - 0.18 11.2 1.4 0.84 9.0 0.8 2.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Bromodomain PF00439.20 CDO72033.1 - 9.3e-23 79.9 0.0 1.8e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain NUP PF06516.6 CDO72036.1 - 2.2e-115 384.8 0.0 2.6e-115 384.5 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Glyco_transf_15 PF01793.11 CDO72037.1 - 1.2e-118 395.8 9.9 4.6e-79 265.7 5.2 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Acid_PPase PF12689.2 CDO72039.1 - 9.9e-33 113.1 0.0 1.1e-30 106.4 0.0 2.0 1 1 1 2 2 2 2 Acid Phosphatase F-box-like PF12937.2 CDO72040.1 - 1.5e-08 34.1 5.0 2.6e-08 33.4 2.1 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 CDO72040.1 - 0.0011 18.4 0.5 0.079 12.6 0.0 3.7 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) Dimer_Tnp_hAT PF05699.9 CDO72042.1 - 8.8e-17 60.5 0.0 1.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 CDO72042.1 - 0.00012 21.9 0.4 0.00027 20.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DUF2197 PF09963.4 CDO72042.1 - 0.1 12.5 0.2 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) Dimer_Tnp_hAT PF05699.9 CDO72044.1 - 1.3e-12 47.1 0.0 3.8e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 CDO72044.1 - 0.012 15.5 0.1 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Abhydrolase_5 PF12695.2 CDO72045.1 - 4.1e-18 65.5 0.0 7.1e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO72045.1 - 1.6e-15 57.6 1.3 5.5e-15 55.8 0.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CDO72045.1 - 3.1e-08 33.4 0.0 6.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 CDO72045.1 - 4.4e-07 29.6 0.0 3.2e-05 23.6 0.0 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CDO72045.1 - 0.0012 19.1 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.13 CDO72045.1 - 0.0018 17.7 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.7 CDO72045.1 - 0.017 13.8 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 CDO72045.1 - 0.019 14.8 0.0 0.048 13.5 0.0 1.7 1 1 0 1 1 1 0 Putative lysophospholipase DUF3089 PF11288.3 CDO72045.1 - 0.023 13.8 0.0 0.06 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Ser_hydrolase PF06821.8 CDO72045.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Peptidase_S9 PF00326.16 CDO72045.1 - 0.065 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 CDO72045.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 CDO72045.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein HCO3_cotransp PF00955.16 CDO72046.1 - 7.5e-55 186.5 7.2 2.9e-29 102.1 1.9 3.1 2 1 1 3 3 3 3 HCO3- transporter family FMO-like PF00743.14 CDO72046.1 - 4.7e-30 104.2 0.0 6.2e-19 67.5 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CDO72046.1 - 4.5e-13 49.7 0.0 7.7e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO72046.1 - 0.00032 20.6 1.2 0.0036 17.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDO72046.1 - 0.0013 18.6 0.0 0.3 10.9 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDO72046.1 - 0.0048 16.0 0.1 0.42 9.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 CDO72046.1 - 0.0067 16.2 0.0 0.0067 16.2 0.0 3.0 5 0 0 5 5 5 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 CDO72046.1 - 0.039 12.8 0.0 4 6.2 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) EHN PF06441.7 CDO72047.1 - 4.1e-34 116.8 0.5 2.3e-33 114.4 0.1 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CDO72047.1 - 4.8e-10 39.7 1.2 1e-09 38.6 0.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO72047.1 - 1.9e-08 34.1 0.0 3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold EHN PF06441.7 CDO72048.1 - 2.5e-33 114.3 1.1 5.6e-33 113.2 0.1 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CDO72048.1 - 4e-11 43.2 0.6 7.1e-11 42.4 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO72048.1 - 4.3e-09 36.2 0.1 6.8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4269 PF14091.1 CDO72048.1 - 0.058 13.3 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) EHN PF06441.7 CDO72049.1 - 5.3e-32 110.0 0.1 5.3e-32 110.0 0.1 2.5 3 0 0 3 3 3 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CDO72049.1 - 8.1e-06 25.8 1.5 2.3e-05 24.4 0.6 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family AstB PF04996.7 CDO72050.1 - 0.033 13.0 0.2 0.039 12.7 0.1 1.1 1 0 0 1 1 1 0 Succinylarginine dihydrolase RCR PF12273.3 CDO72051.1 - 0.026 15.0 0.3 0.052 14.0 0.2 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4229 PF14012.1 CDO72051.1 - 0.051 13.4 0.4 0.1 12.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) TrbC PF04956.8 CDO72051.1 - 0.076 13.0 0.3 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family SKG6 PF08693.5 CDO72051.1 - 0.16 11.2 0.8 0.33 10.2 0.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1517 PF07466.6 CDO72051.1 - 1.7 7.5 8.4 0.031 13.2 1.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) GATase_4 PF13230.1 CDO72052.1 - 0.046 12.3 0.0 0.23 10.0 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Epimerase PF01370.16 CDO72054.1 - 3.3e-21 75.8 0.0 3.9e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO72054.1 - 3.1e-11 42.4 0.0 4.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CDO72054.1 - 2.9e-08 32.9 0.0 7.3e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 CDO72054.1 - 1e-06 28.7 0.1 2.8e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CDO72054.1 - 1.8e-06 27.1 0.0 3.4e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CDO72054.1 - 4.7e-05 23.4 0.3 7.2e-05 22.8 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CDO72054.1 - 0.02 13.8 0.0 1.1 8.0 0.0 2.6 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein KR PF08659.5 CDO72054.1 - 0.051 13.2 0.8 0.14 11.8 0.2 2.0 2 1 0 2 2 2 0 KR domain Enterotoxin_a PF01375.12 CDO72054.1 - 0.058 12.6 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain F_bP_aldolase PF01116.15 CDO72055.1 - 2e-72 243.7 0.0 2.2e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Aminotran_1_2 PF00155.16 CDO72056.1 - 1.1e-27 96.9 0.0 1.5e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CDO72056.1 - 0.0015 16.9 0.0 0.0023 16.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CDO72056.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 CDO72056.1 - 0.029 13.1 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CDO72056.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MerR PF00376.18 CDO72056.1 - 0.15 11.6 0.0 0.55 9.8 0.0 1.9 1 0 0 1 1 1 0 MerR family regulatory protein RVT_1 PF00078.22 CDO72057.1 - 5.9e-28 97.7 0.0 9.4e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CDO72057.1 - 2.6e-19 69.0 0.0 5.3e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 CDO72057.1 - 1.2e-12 48.2 0.0 3.1e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 CDO72057.1 - 1.3e-06 28.6 0.0 2.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family rve PF00665.21 CDO72064.1 - 2.3e-23 82.5 0.0 4.3e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 CDO72064.1 - 1.5e-14 53.5 0.0 2.9e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO72064.1 - 3.1e-11 43.1 0.0 7.2e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO72064.1 - 0.00016 21.2 0.2 0.00044 19.8 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CDO72064.1 - 0.019 14.4 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RVT_2 PF07727.9 CDO72065.1 - 6.4e-56 189.0 0.0 8.5e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_60s PF00428.14 CDO72066.1 - 1.2e-05 25.6 0.2 1.5e-05 25.2 0.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein CoatB PF10389.4 CDO72066.1 - 1.8 8.4 3.7 2.1 8.2 0.3 2.2 2 1 0 2 2 2 0 Bacteriophage coat protein B Peptidase_M20 PF01546.23 CDO72068.1 - 2.5e-18 66.2 3.5 1.4e-17 63.8 2.4 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CDO72068.1 - 4.7e-12 45.6 0.2 1.7e-11 43.8 0.1 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain UQ_con PF00179.21 CDO72069.1 - 3.2e-17 62.2 0.1 4.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PAP1 PF08601.5 CDO72069.1 - 0.024 14.3 0.9 0.032 13.9 0.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DAP3 PF10236.4 CDO72071.1 - 2.2e-69 233.7 0.0 2.9e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CDO72071.1 - 3.2e-06 27.2 0.0 5.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CDO72071.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CDO72071.1 - 0.0022 18.1 0.0 0.0062 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CDO72071.1 - 0.0025 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase ResIII PF04851.10 CDO72071.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 CDO72071.1 - 0.031 13.7 0.1 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.11 CDO72071.1 - 0.049 12.8 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.1 CDO72071.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CDO72071.1 - 0.085 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 CDO72071.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CDO72071.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.18 CDO72072.1 - 1.1e-103 346.4 0.3 2e-103 345.6 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain ERM PF00769.14 CDO72072.1 - 0.0027 17.2 20.9 0.0068 15.9 14.5 1.7 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Arch_ATPase PF01637.13 CDO72072.1 - 0.075 12.7 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase Macoilin PF09726.4 CDO72072.1 - 0.096 10.9 22.5 0.38 8.9 6.5 2.3 1 1 1 2 2 2 0 Transmembrane protein Reo_sigmaC PF04582.7 CDO72072.1 - 0.19 10.8 9.3 0.082 12.0 0.7 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 CDO72072.1 - 0.56 9.9 24.3 0.14 11.9 7.1 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein WEMBL PF05701.6 CDO72072.1 - 0.67 8.3 29.1 0.18 10.2 14.0 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light APG6 PF04111.7 CDO72072.1 - 0.76 8.7 23.7 0.31 10.0 1.8 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 CDO72072.1 - 1.1 9.0 27.8 0.13 12.1 10.7 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_22 PF13401.1 CDO72072.1 - 1.3 9.1 8.7 15 5.7 0.1 3.2 2 1 0 2 2 2 0 AAA domain ATG16 PF08614.6 CDO72072.1 - 4.4 7.0 28.4 14 5.4 15.5 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TFIIA PF03153.8 CDO72072.1 - 7.8 6.2 15.9 14 5.4 10.8 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3584 PF12128.3 CDO72072.1 - 9.2 3.4 25.8 13 2.9 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exo_endo_phos PF03372.18 CDO72073.1 - 8.9e-13 48.7 0.1 1.5e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CDO72073.1 - 1.4e-08 34.4 0.0 3.7e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 CDO72073.1 - 1.6e-07 31.1 3.6 3.4e-05 23.6 0.3 2.4 2 0 0 2 2 2 2 GRF zinc finger zf-C2H2_jaz PF12171.3 CDO72074.1 - 2.2e-10 40.3 6.0 3.9e-10 39.5 4.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CDO72074.1 - 0.0049 16.9 0.2 0.0049 16.9 0.1 1.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CDO72074.1 - 0.072 13.3 3.5 0.14 12.3 2.4 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CDO72074.1 - 0.09 13.1 1.6 0.23 11.9 1.1 1.7 1 1 0 1 1 1 0 Zinc finger, C2H2 type Anoctamin PF04547.7 CDO72077.1 - 5e-97 325.4 0.0 8.3e-97 324.6 0.0 1.3 1 1 0 1 1 1 1 Calcium-activated chloride channel VHS PF00790.14 CDO72078.1 - 7.5e-34 116.3 0.1 1.2e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 CDO72078.1 - 6.8e-16 57.5 0.1 1.4e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CDO72078.1 - 9.8e-15 53.6 0.0 1.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CDO72078.1 - 2.1e-14 52.7 0.1 4.2e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 CDO72078.1 - 1.2e-06 28.4 1.2 3e-06 27.1 0.8 1.6 1 0 0 1 1 1 1 GAT domain UIM PF02809.15 CDO72078.1 - 0.00048 19.4 2.3 0.0011 18.3 1.6 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif UQ_con PF00179.21 CDO72079.1 - 3.7e-17 62.0 0.0 4e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CDO72079.1 - 0.0024 17.7 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CDO72079.1 - 0.069 12.8 0.1 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 UEV domain Sugar_tr PF00083.19 CDO72080.1 - 4.2e-74 249.7 21.0 4.8e-74 249.5 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO72080.1 - 1.4e-32 112.7 47.4 5.5e-32 110.8 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CDO72080.1 - 3.9e-10 38.5 12.0 1.7e-08 33.1 0.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 CDO72080.1 - 0.092 10.7 4.1 1.4 6.8 0.4 2.3 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Sec6 PF06046.8 CDO72081.1 - 1.5e-152 508.6 6.4 1.5e-152 508.6 4.4 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec6 HECT PF00632.20 CDO72081.1 - 0.005 16.0 0.1 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Vps53_N PF04100.7 CDO72081.1 - 0.0063 15.3 2.8 0.025 13.3 0.8 2.6 2 1 0 2 2 2 1 Vps53-like, N-terminal LXG PF04740.7 CDO72081.1 - 0.23 11.2 3.8 16 5.2 0.0 4.4 4 1 1 5 5 5 0 LXG domain of WXG superfamily Snf7 PF03357.16 CDO72081.1 - 0.45 9.8 7.8 0.13 11.6 0.9 3.3 2 1 0 2 2 2 0 Snf7 Adeno_PIX PF03955.9 CDO72081.1 - 2.9 8.4 5.3 14 6.2 0.3 3.6 3 1 1 4 4 4 0 Adenovirus hexon-associated protein (IX) COG2 PF06148.6 CDO72081.1 - 3 7.7 17.4 5.9 6.7 0.0 6.0 5 2 1 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 MFS_1 PF07690.11 CDO72082.1 - 3.1e-33 114.9 28.3 3.1e-33 114.9 19.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO72082.1 - 8.4e-07 27.9 8.8 8.4e-07 27.9 6.1 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter DUF2101 PF09874.4 CDO72082.1 - 0.024 14.1 0.5 0.042 13.3 0.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) CN_hydrolase PF00795.17 CDO72083.1 - 8e-27 93.7 0.0 1.5e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 CDO72083.1 - 2.6e-23 82.1 0.0 9.9e-23 80.2 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 CDO72083.1 - 0.0026 17.2 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Beta_elim_lyase PF01212.16 CDO72083.1 - 0.06 12.4 0.2 0.19 10.8 0.0 1.8 1 1 1 2 2 2 0 Beta-eliminating lyase PhnG PF06754.7 CDO72083.1 - 0.1 12.2 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG DUF4551 PF15087.1 CDO72084.1 - 3.2 6.0 8.3 3.7 5.7 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NST1 PF13945.1 CDO72084.1 - 8.1 6.4 9.6 4.6 7.2 5.1 1.7 1 1 1 2 2 2 0 Salt tolerance down-regulator DAO PF01266.19 CDO72085.1 - 7.9e-08 31.5 0.2 1.7e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CDO72085.1 - 4.9e-06 25.6 0.4 4.8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 CDO72085.1 - 8.7e-06 25.5 0.2 9.2e-05 22.2 0.1 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 CDO72085.1 - 1e-05 24.7 0.0 2.2e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 CDO72085.1 - 2.6e-05 24.3 0.1 0.00011 22.3 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CDO72085.1 - 4.1e-05 22.8 2.2 0.00011 21.3 1.5 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CDO72085.1 - 0.00012 22.0 0.1 0.00014 21.8 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO72085.1 - 0.0019 18.1 0.1 0.0047 16.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 CDO72085.1 - 0.0025 16.5 0.4 0.0045 15.6 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 CDO72085.1 - 0.0078 15.0 1.3 0.013 14.4 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 CDO72085.1 - 0.018 13.5 1.4 0.037 12.4 1.0 1.7 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 CDO72085.1 - 0.019 15.3 0.2 0.099 13.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lsm_C PF14894.1 CDO72085.1 - 0.048 13.1 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 Lsm C-terminal K_oxygenase PF13434.1 CDO72085.1 - 0.11 11.3 0.1 0.21 10.4 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UDPGT PF00201.13 CDO72086.1 - 1.5e-06 27.0 0.1 1.9e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CDO72086.1 - 0.013 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CDO72086.1 - 0.026 13.7 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 ACC_central PF08326.7 CDO72088.1 - 1.1e-214 714.7 0.0 1.4e-214 714.3 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CDO72088.1 - 1.1e-166 555.0 0.0 1.5e-166 554.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CDO72088.1 - 7.2e-53 179.0 0.0 1.7e-52 177.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CDO72088.1 - 3.3e-26 91.5 0.1 7e-26 90.5 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CDO72088.1 - 5.8e-21 74.4 0.0 3.9e-20 71.8 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CDO72088.1 - 1.4e-12 47.0 0.0 2.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CDO72088.1 - 9e-12 45.0 0.1 2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CDO72088.1 - 5.2e-10 38.5 0.0 1.8e-05 23.6 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 CDO72088.1 - 0.00013 21.8 0.0 0.00046 20.0 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CDO72088.1 - 0.00018 20.9 0.0 0.00036 19.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CDO72088.1 - 0.036 13.4 0.1 0.076 12.3 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain Fer2_4 PF13510.1 CDO72088.1 - 0.2 11.5 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain RimK PF08443.6 CDO72088.1 - 0.2 11.0 0.0 1.3 8.4 0.0 2.2 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Gluconate_2-dh3 PF13618.1 CDO72088.1 - 1.2 9.2 5.1 3.3 7.8 0.0 3.8 3 2 0 3 3 2 0 Gluconate 2-dehydrogenase subunit 3 Ribosomal_L35Ae PF01247.13 CDO72089.1 - 2.9e-42 142.3 0.9 3.3e-42 142.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CDO72089.1 - 0.00054 19.8 0.0 0.094 12.6 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain ArgJ PF01960.13 CDO72090.1 - 1e-144 481.7 0.0 1.2e-144 481.5 0.0 1.0 1 0 0 1 1 1 1 ArgJ family PH_10 PF15411.1 CDO72091.1 - 1.7e-26 92.6 0.0 3.6e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 CDO72091.1 - 0.0029 17.3 0.1 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Serglycin PF04360.7 CDO72091.1 - 0.061 13.0 1.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Serglycin zf-RING_2 PF13639.1 CDO72092.1 - 0.00015 21.4 0.4 0.00029 20.6 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDO72092.1 - 0.083 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger DUF4129 PF13559.1 CDO72093.1 - 0.064 13.2 0.3 0.064 13.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Asp PF00026.18 CDO72095.1 - 8e-11 41.7 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF3827 PF12877.2 CDO72095.1 - 0.09 10.8 0.1 0.12 10.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF3357 PF11837.3 CDO72095.1 - 0.093 12.5 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Protocadherin PF08374.6 CDO72095.1 - 0.13 11.8 0.1 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protocadherin HIG_1_N PF04588.8 CDO72097.1 - 1.8e-13 49.9 0.2 3e-13 49.2 0.2 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Urm1 PF09138.6 CDO72098.1 - 3.1e-34 116.9 0.0 4.4e-28 97.2 0.0 2.1 2 0 0 2 2 2 2 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CDO72098.1 - 0.00014 22.1 0.0 0.00022 21.5 0.0 1.4 1 0 0 1 1 1 1 ThiS family RR_TM4-6 PF06459.7 CDO72099.1 - 0.05 13.5 1.5 0.057 13.3 1.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RVT_2 PF07727.9 CDO72100.1 - 2.7e-12 46.2 0.0 3.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_2 PF14227.1 CDO72101.1 - 9.3e-13 47.7 1.3 9.3e-13 47.7 0.9 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO72101.1 - 5.7e-09 35.7 1.1 5.7e-09 35.7 0.8 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO72101.1 - 5.1e-05 22.8 6.4 0.00056 19.4 4.4 2.3 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO72101.1 - 0.0031 16.8 0.6 0.0031 16.8 0.4 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 CDO72101.1 - 0.005 16.7 4.4 0.014 15.2 3.1 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDO72101.1 - 0.098 12.3 4.6 0.23 11.1 3.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Myc_N PF01056.13 CDO72102.1 - 0.066 12.3 0.6 0.075 12.1 0.4 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Peroxidase_2 PF01328.12 CDO72103.1 - 7e-18 64.3 0.1 2.3e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 Peroxidase, family 2 Tho2 PF11262.3 CDO72104.1 - 0.017 14.1 0.0 0.49 9.4 0.0 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF3475 PF11961.3 CDO72104.1 - 0.097 12.5 0.4 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3475) LRR_8 PF13855.1 CDO72104.1 - 0.24 11.1 2.2 6.5 6.5 0.0 3.4 2 1 1 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 CDO72104.1 - 2.6 7.7 6.1 22 4.8 0.2 4.1 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Sds3 PF08598.6 CDO72105.1 - 5.7e-19 68.4 3.3 5.7e-19 68.4 2.3 3.0 2 1 0 2 2 2 1 Sds3-like Peroxidase_2 PF01328.12 CDO72106.1 - 2.2e-19 69.2 0.0 4.9e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Peroxidase, family 2 NUDIX PF00293.23 CDO72107.1 - 8.1e-07 28.7 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain RNA_Me_trans PF04252.8 CDO72108.1 - 3.8e-31 108.0 0.0 1.6e-27 96.2 0.0 2.0 2 0 0 2 2 2 2 Predicted SAM-dependent RNA methyltransferase Aldo_ket_red PF00248.16 CDO72109.1 - 3.9e-64 216.1 0.0 4.5e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 CDO72110.1 - 3.7e-64 216.2 0.0 4.2e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_11 PF13414.1 CDO72111.1 - 1.7e-11 43.5 1.7 1.1e-05 24.9 0.1 2.9 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 CDO72111.1 - 1.2e-07 31.9 3.9 0.0067 16.7 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO72111.1 - 6.2e-07 29.4 3.7 0.0021 18.5 0.1 4.9 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDO72111.1 - 8.9e-07 28.3 1.9 0.051 13.5 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDO72111.1 - 9.5e-07 28.1 0.3 0.065 12.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDO72111.1 - 1.9e-06 28.3 5.4 0.036 14.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CDO72111.1 - 3e-06 26.6 0.0 0.037 13.8 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDO72111.1 - 5e-06 26.2 4.0 0.001 18.9 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDO72111.1 - 0.00051 20.0 3.8 0.4 11.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDO72111.1 - 0.0031 17.4 1.5 0.21 11.5 0.4 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat ChAPs PF09295.5 CDO72111.1 - 0.046 12.4 0.0 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.1 CDO72111.1 - 0.13 11.2 3.0 5.3 6.0 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Pterin_bind PF00809.17 CDO72112.1 - 7.7e-46 156.1 0.0 1.5e-45 155.1 0.0 1.5 1 0 0 1 1 1 1 Pterin binding enzyme FolB PF02152.13 CDO72112.1 - 6.2e-36 123.0 0.0 4.1e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.15 CDO72112.1 - 1.5e-33 115.2 0.0 4.4e-33 113.7 0.0 1.8 1 1 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Pkinase PF00069.20 CDO72113.1 - 1.2e-60 204.8 0.0 1.9e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO72113.1 - 2.2e-44 151.5 0.0 5e-44 150.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 CDO72113.1 - 2.2e-23 82.7 0.1 3.5e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.1 CDO72113.1 - 4.3e-05 22.6 0.0 0.00016 20.7 0.0 1.9 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 CDO72113.1 - 0.0048 16.6 0.9 0.015 15.0 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Plus-3 PF03126.13 CDO72114.1 - 1.2e-25 89.6 0.1 2.8e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain WD40 PF00400.27 CDO72115.1 - 1.6e-29 100.6 8.8 9.9e-11 41.0 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 CDO72115.1 - 3.7e-27 94.1 10.4 6e-27 93.5 7.2 1.3 1 0 0 1 1 1 1 Sof1-like domain BBS2_N PF14781.1 CDO72115.1 - 0.051 13.1 0.0 2.9 7.5 0.0 2.5 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal peroxidase PF00141.18 CDO72117.1 - 2.2e-06 27.3 0.0 2.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase F-box-like PF12937.2 CDO72119.1 - 0.0039 16.8 0.0 0.0085 15.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like DEAD PF00270.24 CDO72120.1 - 4.7e-41 140.0 0.0 1.1e-40 138.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CDO72120.1 - 3e-26 90.7 0.2 7e-26 89.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CDO72120.1 - 1.7e-20 72.6 0.0 3.8e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_5 PF07728.9 CDO72121.1 - 1.2e-65 219.4 0.0 2.6e-27 95.2 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CDO72121.1 - 0.02 15.0 0.0 0.075 13.2 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDO72121.1 - 0.062 13.4 0.1 0.39 10.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 CDO72121.1 - 0.16 11.8 0.1 0.83 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) CagA PF03507.8 CDO72121.1 - 0.33 10.7 0.0 2.4 7.9 0.0 2.0 2 0 0 2 2 2 0 CagA exotoxin Aminotran_1_2 PF00155.16 CDO72122.1 - 2.7e-38 131.8 0.0 3.4e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CDO72122.1 - 0.017 13.4 0.0 0.033 12.4 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Myb_DNA-binding PF00249.26 CDO72125.1 - 4.4e-07 29.8 0.2 7.6e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO72125.1 - 9.7e-05 22.4 0.4 0.00089 19.3 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Cir_N PF10197.4 CDO72125.1 - 0.036 14.0 0.0 0.036 14.0 0.0 3.3 3 0 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR Polysacc_synt_4 PF04669.8 CDO72126.1 - 5.8e-24 84.5 3.5 4.3e-23 81.6 2.4 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis adh_short PF00106.20 CDO72127.1 - 1.7e-22 80.1 0.1 2.9e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO72127.1 - 1.4e-12 47.9 0.2 2.2e-10 40.7 0.1 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO72127.1 - 4.1e-07 29.8 0.1 7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CDO72127.1 - 0.00051 20.1 0.0 0.00084 19.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 CDO72127.1 - 0.0044 17.4 0.3 0.008 16.5 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 CDO72127.1 - 0.0045 15.9 0.1 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 CDO72127.1 - 0.015 15.4 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CDO72127.1 - 0.019 15.3 0.5 0.041 14.2 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CDO72127.1 - 0.028 14.0 0.3 0.039 13.6 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CDO72127.1 - 0.028 13.4 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_tran_WecB PF03808.8 CDO72127.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Thaumatin PF00314.12 CDO72128.1 - 2.4e-56 190.5 10.7 2.9e-56 190.2 7.4 1.1 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.16 CDO72128.1 - 0.039 13.5 0.0 0.098 12.2 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat ThiF PF00899.16 CDO72129.1 - 1.2e-34 119.1 0.3 1.8e-34 118.4 0.2 1.3 1 0 0 1 1 1 1 ThiF family 3HCDH_N PF02737.13 CDO72129.1 - 0.00024 20.8 0.0 0.00051 19.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CDO72129.1 - 0.00049 20.3 0.2 0.0011 19.2 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 CDO72129.1 - 0.0046 15.9 0.6 0.013 14.4 0.4 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase DAO PF01266.19 CDO72129.1 - 0.012 14.5 0.2 0.019 13.8 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 CDO72129.1 - 0.076 12.3 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 CDO72129.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 CDO72129.1 - 0.15 11.1 0.3 0.22 10.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 CDO72129.1 - 0.17 12.0 0.5 0.56 10.3 0.3 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Vps26 PF03643.10 CDO72131.1 - 7.9e-132 438.1 2.2 9.2e-132 437.9 1.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CDO72131.1 - 0.00089 19.1 2.2 0.16 11.7 0.1 3.6 2 1 2 4 4 4 1 Arrestin (or S-antigen), N-terminal domain zf-C2H2_4 PF13894.1 CDO72132.1 - 0.83 10.1 12.4 3.7 8.1 2.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger MatC_N PF07158.6 CDO72133.1 - 0.019 14.8 0.1 0.025 14.3 0.1 1.3 1 1 0 1 1 1 0 Dicarboxylate carrier protein MatC N-terminus Abhydrolase_4 PF08386.5 CDO72134.1 - 2.9e-20 72.0 0.0 6.3e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 CDO72134.1 - 1.4e-18 67.2 0.0 2e-12 47.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDO72134.1 - 6.5e-12 45.8 2.0 5.1e-11 42.8 1.4 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO72134.1 - 0.0013 18.4 0.0 0.034 13.8 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO72135.1 - 6.2e-13 48.8 0.0 3.2e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 CDO72135.1 - 1.5e-05 24.7 0.1 0.0029 17.4 0.0 2.6 1 1 1 2 2 2 2 TAP-like protein Abhydrolase_6 PF12697.2 CDO72135.1 - 0.00091 19.1 0.5 0.0027 17.6 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family TSA PF03249.8 CDO72136.1 - 0.083 11.4 4.3 0.1 11.1 3.0 1.0 1 0 0 1 1 1 0 Type specific antigen DUF4246 PF14033.1 CDO72136.1 - 0.09 11.3 0.8 0.088 11.3 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DUF755 PF05501.6 CDO72136.1 - 0.57 10.2 4.4 0.72 9.9 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF972 PF06156.8 CDO72136.1 - 0.58 10.5 4.1 0.88 9.9 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3886 PF13025.1 CDO72136.1 - 1.9 8.4 15.7 3.2 7.7 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Zn_clus PF00172.13 CDO72136.1 - 3.6 7.5 10.5 6.9 6.6 7.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop14 PF04147.7 CDO72136.1 - 4.7 5.0 11.3 5.1 4.8 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 CDO72136.1 - 4.9 7.1 11.8 6.3 6.7 8.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BTV_NS2 PF04514.7 CDO72136.1 - 5.4 5.8 10.7 6.6 5.5 7.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Atg14 PF10186.4 CDO72136.1 - 6.2 5.6 7.4 7.4 5.4 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 rve PF00665.21 CDO72137.1 - 7.3e-20 71.2 0.0 1.4e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO72137.1 - 1.8e-08 33.9 0.0 3.2e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ferrochelatase PF00762.14 CDO72137.1 - 0.035 13.0 0.5 4.5 6.1 0.1 2.4 2 1 1 3 3 3 0 Ferrochelatase eIF-3c_N PF05470.7 CDO72138.1 - 0.45 8.5 5.8 0.51 8.3 4.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4612 PF15389.1 CDO72138.1 - 0.48 11.0 8.1 0.097 13.2 3.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) Erp_C PF06780.6 CDO72138.1 - 1.4 8.7 6.2 0.91 9.3 0.1 2.2 2 0 0 2 2 2 0 Erp protein C-terminus DUF2390 PF09523.5 CDO72138.1 - 9.8 6.4 15.0 17 5.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Transposase_21 PF02992.9 CDO72139.1 - 1.1e-22 80.3 0.0 1.8e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF2046 PF09755.4 CDO72140.1 - 0.0067 15.3 0.2 0.014 14.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) IncA PF04156.9 CDO72140.1 - 0.56 9.7 7.7 1.3 8.6 1.3 2.4 1 1 0 2 2 2 0 IncA protein APG6 PF04111.7 CDO72140.1 - 3.3 6.6 5.9 4.1 6.3 0.1 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Sulfolobus_pRN PF05584.6 CDO72144.1 - 0.13 12.2 0.1 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein Flg_hook PF02120.11 CDO72144.1 - 0.14 11.8 2.2 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK WD40 PF00400.27 CDO72145.1 - 3.6e-10 39.3 2.6 0.00034 20.3 0.0 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.6 CDO72145.1 - 0.012 15.2 0.0 0.66 9.6 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF3681 PF12442.3 CDO72145.1 - 0.88 9.7 3.9 2.2 8.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Sad1_UNC PF07738.8 CDO72147.1 - 4.8e-21 74.9 0.0 1.5e-19 70.0 0.0 2.1 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF3467 PF11950.3 CDO72149.1 - 0.058 13.4 0.6 0.39 10.7 0.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3467) Myb_DNA-bind_3 PF12776.2 CDO72150.1 - 8.3e-05 23.1 0.6 0.00013 22.5 0.1 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CDO72150.1 - 0.00051 20.1 0.5 0.0015 18.6 0.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.1 CDO72151.1 - 4.2e-23 81.6 0.0 5.2e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CDO72151.1 - 0.0036 16.6 0.0 0.0063 15.9 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 CDO72151.1 - 0.007 15.9 0.1 0.026 14.0 0.1 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 CDO72151.1 - 0.021 15.0 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain TAXi_N PF14543.1 CDO72153.1 - 0.09 12.7 0.0 0.39 10.6 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Asp PF00026.18 CDO72153.1 - 0.14 11.3 0.1 0.7 9.0 0.1 2.0 3 0 0 3 3 3 0 Eukaryotic aspartyl protease UBN2_2 PF14227.1 CDO72155.1 - 5.7e-14 51.7 0.0 1.3e-13 50.5 0.0 1.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO72155.1 - 1.2e-11 44.4 0.0 1.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO72155.1 - 1.3e-05 24.8 2.7 2.6e-05 23.9 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CDO72155.1 - 0.00017 20.9 0.2 0.00042 19.7 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF4219 PF13961.1 CDO72155.1 - 0.037 13.4 0.0 0.082 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC_3 PF13917.1 CDO72155.1 - 0.12 12.1 0.5 0.27 10.9 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle UBN2_2 PF14227.1 CDO72156.1 - 3.4e-14 52.4 0.1 8.7e-14 51.1 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO72156.1 - 7.5e-10 38.6 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO72157.1 - 5.5e-06 26.0 2.7 8.5e-06 25.4 1.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CDO72157.1 - 5.7e-05 22.5 0.3 0.00013 21.3 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDO72157.1 - 0.083 12.6 0.5 0.083 12.6 0.3 1.6 2 0 0 2 2 2 0 Zinc knuckle SAM_2 PF07647.12 CDO72159.1 - 1.9e-10 40.4 0.0 5e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CDO72159.1 - 4.3e-06 26.8 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HET PF06985.6 CDO72160.1 - 1.2e-10 41.6 0.2 1e-06 28.9 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DIOX_N PF14226.1 CDO72161.1 - 1.2e-30 106.4 0.0 1.8e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO72161.1 - 1e-17 64.1 0.0 1.8e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 CDO72162.1 - 4.4e-19 68.9 2.7 6.1e-18 65.2 1.9 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO72162.1 - 3.8e-08 33.3 0.0 3.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO72162.1 - 5.7e-07 29.3 0.4 1.3e-06 28.2 0.3 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CDO72162.1 - 0.072 13.0 0.2 0.6 10.0 0.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding Pyr_redox PF00070.22 CDO72162.1 - 0.085 13.2 0.7 0.16 12.3 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CDO72162.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Dynamin_N PF00350.18 CDO72164.1 - 3.8e-20 72.3 0.1 8e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CDO72164.1 - 2.4e-11 43.6 0.0 1.2e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CDO72164.1 - 1.1e-08 34.7 0.6 8.4e-08 31.8 0.4 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CDO72164.1 - 0.00016 22.1 0.2 0.021 15.3 0.0 2.9 2 1 0 2 2 2 1 Miro-like protein cobW PF02492.14 CDO72164.1 - 0.0025 17.2 0.2 0.076 12.4 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.8 CDO72164.1 - 0.003 16.4 0.0 0.0054 15.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 CDO72164.1 - 0.0058 16.1 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arf PF00025.16 CDO72164.1 - 0.063 12.5 0.2 2.4 7.3 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family FeoB_N PF02421.13 CDO72164.1 - 0.1 11.8 0.1 3.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 CDO72164.1 - 0.13 11.3 0.0 0.53 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 CDO72164.1 - 0.21 11.0 5.2 1 8.8 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Ribosomal_L5_C PF00673.16 CDO72165.1 - 5.3e-16 58.1 0.0 1.1e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Lactamase_B PF00753.22 CDO72165.1 - 4.4e-10 39.5 0.4 1e-09 38.3 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CDO72165.1 - 0.00073 19.1 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Peptidase_M64 PF09471.5 CDO72166.1 - 5e-23 82.0 0.0 8.2e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 IgA Peptidase M64 Pkinase PF00069.20 CDO72167.1 - 4.5e-69 232.4 0.0 7.9e-69 231.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO72167.1 - 3e-49 167.4 0.0 6.8e-49 166.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO72167.1 - 0.0006 18.8 0.1 0.0085 15.0 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Adaptin_N PF01602.15 CDO72167.1 - 1.1 7.5 8.4 0.52 8.5 0.1 3.4 3 1 0 3 3 3 0 Adaptin N terminal region Ribosomal_L1 PF00687.16 CDO72168.1 - 1e-55 188.4 0.3 1e-55 188.4 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family ADH_zinc_N PF00107.21 CDO72169.1 - 6e-30 103.4 0.1 9.5e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO72169.1 - 1.4e-17 64.7 0.0 3.7e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO72169.1 - 7e-15 54.7 0.4 1.4e-12 47.3 0.0 2.9 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain LRR_4 PF12799.2 CDO72170.1 - 0.0007 19.1 4.8 10 5.8 0.0 6.3 6 1 0 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO72170.1 - 0.00086 19.0 4.1 3.5 7.4 0.0 5.5 5 1 1 6 6 6 1 Leucine rich repeat LRR_2 PF07723.8 CDO72170.1 - 0.0074 16.7 2.4 1.2e+02 3.3 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat MIF4G PF02854.14 CDO72171.1 - 0.0039 16.6 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain COesterase PF00135.23 CDO72172.1 - 7e-98 328.6 0.0 9.4e-98 328.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CDO72172.1 - 8.3e-06 25.5 0.3 4e-05 23.2 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DAP_C PF07932.7 CDO72172.1 - 0.024 14.7 0.1 0.077 13.1 0.1 1.7 2 0 0 2 2 2 0 D-aminopeptidase, domain C MFS_1 PF07690.11 CDO72173.1 - 4.1e-17 61.9 43.5 4e-09 35.6 15.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDO72173.1 - 0.012 14.0 20.2 0.02 13.2 1.2 2.2 2 0 0 2 2 2 0 MFS/sugar transport protein Peptidase_U4 PF03419.8 CDO72173.1 - 2.9 6.8 5.3 4.6 6.2 3.7 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA LRR_8 PF13855.1 CDO72174.1 - 0.0015 18.2 2.3 0.92 9.3 0.0 4.0 2 2 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CDO72174.1 - 0.011 15.2 3.2 1.4 8.5 0.4 4.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) DUF676 PF05057.9 CDO72176.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CDO72176.1 - 0.0073 15.9 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CDO72176.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family ATP-synt_B PF00430.13 CDO72176.1 - 0.37 10.5 1.3 0.72 9.6 0.9 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) AA_permease_2 PF13520.1 CDO72177.1 - 1.8e-50 171.7 40.3 2.2e-50 171.4 27.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CDO72177.1 - 3.7e-13 48.6 41.1 9.5e-09 34.0 16.9 2.1 2 0 0 2 2 2 2 Amino acid permease DUF3733 PF12534.3 CDO72177.1 - 7.8 5.8 8.2 0.81 9.0 0.1 3.2 4 0 0 4 4 4 0 Leucine-rich repeat containing protein 8 DDE_3 PF13358.1 CDO72178.1 - 6.7e-14 51.8 0.0 3.8e-13 49.4 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease adh_short PF00106.20 CDO72179.1 - 1.4e-27 96.6 0.1 1.8e-27 96.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO72179.1 - 3.7e-13 49.8 0.0 4.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO72179.1 - 3.4e-08 33.3 0.1 5.1e-08 32.7 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CDO72179.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 CDO72179.1 - 0.059 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3012 PF11216.3 CDO72179.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) LRR_4 PF12799.2 CDO72180.1 - 0.15 11.6 3.7 12 5.6 0.1 4.0 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 CDO72181.1 - 0.0031 17.2 4.0 0.0055 16.4 0.9 2.9 2 1 0 2 2 2 1 F-box-like ELFV_dehydrog PF00208.16 CDO72182.1 - 6.5e-49 166.7 0.0 9.5e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CDO72182.1 - 3.7e-19 67.7 0.0 3.4e-14 51.3 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase HET PF06985.6 CDO72183.1 - 6.4e-10 39.3 0.4 1.3e-07 31.8 0.3 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_20 PF00728.17 CDO72185.1 - 3.4e-77 259.9 0.1 1.4e-75 254.7 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CDO72185.1 - 1.8e-15 57.7 0.0 3.5e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CDO72185.1 - 9.3e-07 29.4 0.1 2.6e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 TSC22 PF01166.13 CDO72186.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Glyco_hydro_20 PF00728.17 CDO72187.1 - 3.5e-88 296.1 0.0 4.1e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Cellulase PF00150.13 CDO72187.1 - 0.01 15.0 0.1 0.31 10.1 0.0 2.2 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) ENTH PF01417.15 CDO72188.1 - 5.4e-46 155.5 0.1 8e-46 154.9 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CDO72188.1 - 0.00012 20.8 0.0 0.00017 20.4 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 CDO72188.1 - 0.029 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 VHS domain BLOC1_2 PF10046.4 CDO72189.1 - 0.00089 19.3 0.1 0.0022 18.0 0.1 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4515 PF14988.1 CDO72189.1 - 0.0017 18.0 0.1 0.0017 18.0 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) DUF2360 PF10152.4 CDO72189.1 - 0.005 17.1 7.2 0.024 14.9 5.0 2.1 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) DUF1664 PF07889.7 CDO72189.1 - 0.006 16.3 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 CDO72189.1 - 0.008 16.3 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.3 CDO72189.1 - 0.016 14.9 0.7 0.029 14.1 0.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 CDO72189.1 - 0.034 14.0 1.4 0.32 10.9 0.1 2.3 2 0 0 2 2 2 0 FlxA-like protein Filament PF00038.16 CDO72189.1 - 0.036 13.5 0.1 0.06 12.8 0.1 1.2 1 0 0 1 1 1 0 Intermediate filament protein Mito_fiss_reg PF05308.6 CDO72189.1 - 0.046 13.0 4.6 0.095 12.0 3.2 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1202 PF06717.6 CDO72189.1 - 0.047 12.9 0.1 0.08 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Mod_r PF07200.8 CDO72189.1 - 0.061 13.2 0.2 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Spectrin PF00435.16 CDO72189.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Spectrin repeat IncA PF04156.9 CDO72189.1 - 0.089 12.3 0.9 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 IncA protein DUF4164 PF13747.1 CDO72189.1 - 0.097 12.8 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Myosin_tail_1 PF01576.14 CDO72189.1 - 0.11 10.1 0.1 0.17 9.5 0.1 1.2 1 0 0 1 1 1 0 Myosin tail GerPC PF10737.4 CDO72189.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Spore germination protein GerPC FlaC_arch PF05377.6 CDO72189.1 - 0.19 11.6 0.5 10 6.1 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 CDO72189.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.4 CDO72189.1 - 0.22 11.4 1.1 6.5 6.7 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein Prefoldin_2 PF01920.15 CDO72189.1 - 0.52 10.0 2.9 0.65 9.7 0.3 2.1 2 1 1 3 3 2 0 Prefoldin subunit DUF605 PF04652.11 CDO72189.1 - 9.3 5.5 12.6 0.72 9.1 5.4 1.6 2 0 0 2 2 2 0 Vta1 like RNA_pol_Rpb4 PF03874.11 CDO72191.1 - 1.4e-21 76.6 0.3 2.4e-21 75.8 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF4455 PF14643.1 CDO72191.1 - 0.028 13.0 1.0 0.11 11.0 0.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4455) NOT2_3_5 PF04153.13 CDO72192.1 - 4.8e-34 117.1 0.7 4.8e-34 117.1 0.5 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family COesterase PF00135.23 CDO72193.1 - 9.7e-71 239.0 0.0 8.4e-43 146.8 0.0 2.9 2 1 0 2 2 2 2 Carboxylesterase family TrkH PF02386.11 CDO72194.1 - 1.4e-65 221.2 2.4 2.5e-50 171.0 0.0 2.0 1 1 1 2 2 2 2 Cation transport protein WD40 PF00400.27 CDO72195.1 - 3.6e-07 29.8 1.5 0.0034 17.2 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat AAA PF00004.24 CDO72197.1 - 1.8e-39 134.9 0.0 3.1e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDO72197.1 - 4.4e-07 29.1 0.0 1.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CDO72197.1 - 6.9e-06 26.8 0.0 2.4e-05 25.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CDO72197.1 - 2e-05 24.5 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CDO72197.1 - 2e-05 24.7 0.1 0.0014 18.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 CDO72197.1 - 2.9e-05 24.0 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CDO72197.1 - 4.9e-05 23.3 0.2 0.0021 18.0 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 CDO72197.1 - 8e-05 22.3 0.4 0.001 18.7 0.3 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CDO72197.1 - 9.5e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDO72197.1 - 0.00018 20.6 0.0 0.00033 19.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 CDO72197.1 - 0.00024 21.1 0.0 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CDO72197.1 - 0.00031 19.9 0.2 0.0015 17.7 0.2 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CDO72197.1 - 0.00034 20.0 0.1 0.00066 19.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CDO72197.1 - 0.00058 20.1 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CDO72197.1 - 0.0012 18.3 0.4 0.072 12.4 0.2 2.3 1 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CDO72197.1 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Rad17 PF03215.10 CDO72197.1 - 0.0017 17.1 0.0 0.0023 16.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 CDO72197.1 - 0.0029 17.7 0.0 0.006 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 CDO72197.1 - 0.0034 16.1 0.1 0.0054 15.5 0.1 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_10 PF12846.2 CDO72197.1 - 0.0038 16.7 0.2 0.52 9.7 0.0 2.5 1 1 1 2 2 2 1 AAA-like domain NACHT PF05729.7 CDO72197.1 - 0.0094 15.6 0.1 0.027 14.1 0.1 1.8 2 0 0 2 2 1 1 NACHT domain ABC_tran PF00005.22 CDO72197.1 - 0.016 15.4 0.0 0.054 13.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 CDO72197.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CDO72197.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 CDO72197.1 - 0.029 13.4 0.0 1.4 8.0 0.0 2.8 2 1 1 3 3 3 0 KaiC SKI PF01202.17 CDO72197.1 - 0.032 14.0 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase Arch_ATPase PF01637.13 CDO72197.1 - 0.043 13.5 0.0 0.42 10.2 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 CDO72197.1 - 0.048 13.1 0.0 0.17 11.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 CDO72197.1 - 0.05 13.3 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain ATP-synt_ab PF00006.20 CDO72197.1 - 0.05 13.0 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_3 PF07726.6 CDO72197.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 CDO72197.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 CDO72197.1 - 0.086 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 CDO72197.1 - 0.09 12.4 0.0 0.32 10.5 0.0 1.8 1 1 0 1 1 1 0 Bacterial dnaA protein tRNA_lig_kinase PF08303.6 CDO72197.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain PduV-EutP PF10662.4 CDO72197.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.11 CDO72197.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Guanylate_kin PF00625.16 CDO72197.1 - 0.14 11.5 0.0 0.52 9.7 0.0 2.0 3 0 0 3 3 1 0 Guanylate kinase DUF815 PF05673.8 CDO72197.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Transposase_21 PF02992.9 CDO72198.1 - 8.9e-17 60.9 0.0 7.6e-16 57.8 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 DUF2457 PF10446.4 CDO72198.1 - 0.00027 19.7 8.5 0.00046 19.0 5.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) DUF4218 PF13960.1 CDO72198.1 - 0.0024 17.3 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RXT2_N PF08595.6 CDO72198.1 - 4.5 7.0 9.4 43 3.8 5.6 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 CDO72198.1 - 7.4 6.1 8.2 14 5.2 5.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RVT_1 PF00078.22 CDO72200.1 - 2.9e-24 85.6 0.0 5.1e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO72200.1 - 3.9e-19 68.9 0.0 1.5e-18 66.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.6 CDO72200.1 - 1.7e-05 24.7 0.0 3.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CDO72200.1 - 0.0003 21.2 0.0 0.00056 20.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.19 CDO72200.1 - 0.0012 18.5 3.1 0.0033 17.0 0.4 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.1 CDO72200.1 - 0.23 11.3 0.0 0.47 10.3 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 CDO72201.1 - 6.4e-07 29.3 4.2 7.7e-07 29.0 0.0 2.7 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO72201.1 - 2.3e-06 27.2 2.5 4.5e-06 26.3 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle GOLGA2L5 PF15070.1 CDO72201.1 - 0.0025 16.4 0.3 0.0037 15.8 0.2 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 FimP PF09766.4 CDO72201.1 - 0.047 12.7 1.1 0.096 11.7 0.8 1.4 1 0 0 1 1 1 0 Fms-interacting protein zf-CCHC_4 PF14392.1 CDO72201.1 - 0.06 13.0 1.3 0.11 12.1 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF1192 PF06698.6 CDO72201.1 - 0.069 12.9 0.6 0.069 12.9 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) PV-1 PF06637.6 CDO72201.1 - 0.076 11.5 0.5 0.12 10.9 0.4 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) TBPIP PF07106.8 CDO72201.1 - 0.096 12.2 0.5 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-CCHC_2 PF13696.1 CDO72201.1 - 0.14 11.6 0.5 0.3 10.6 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4404 PF14357.1 CDO72201.1 - 0.17 12.2 6.8 0.63 10.4 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF883 PF05957.8 CDO72201.1 - 1.4 9.4 4.5 3.4 8.1 3.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Asp PF00026.18 CDO72202.1 - 1.7e-20 73.5 0.0 3e-20 72.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Metallophos_2 PF12850.2 CDO72203.1 - 1.6e-06 28.0 0.0 3.1e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CDO72203.1 - 0.00017 21.0 0.2 0.00047 19.5 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Trehalase PF01204.13 CDO72204.1 - 6e-98 328.7 0.1 1.4e-85 287.8 0.0 2.4 2 1 0 2 2 2 2 Trehalase GDE_C PF06202.9 CDO72204.1 - 0.0091 14.7 0.0 0.033 12.8 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase RRM_1 PF00076.17 CDO72205.1 - 1.9e-08 33.8 0.0 4.9e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 CDO72205.1 - 7.4e-08 32.3 0.1 1.7e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 PWI domain RRM_6 PF14259.1 CDO72205.1 - 4.4e-05 23.3 0.0 8.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 4F5 PF04419.9 CDO72205.1 - 9.3 7.0 12.3 1.8 9.3 2.9 3.0 2 0 0 2 2 2 0 4F5 protein family Sad1_UNC PF07738.8 CDO72207.1 - 5.7e-31 107.1 0.0 1e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ATP-synt_C PF00137.16 CDO72207.1 - 2.7e-29 100.8 30.7 2.2e-17 62.6 8.6 2.4 2 0 0 2 2 2 2 ATP synthase subunit C p450 PF00067.17 CDO72208.1 - 7.9e-78 262.0 0.0 1.1e-77 261.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 CDO72208.1 - 9.1e-35 120.0 0.0 1.5e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CDO72208.1 - 3.2e-24 85.5 0.0 6.3e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CDO72208.1 - 1.8e-11 44.5 0.0 4e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 CDO72208.1 - 7e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_5 PF12724.2 CDO72208.1 - 0.029 14.3 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_3 PF12641.2 CDO72208.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain p450 PF00067.17 CDO72209.1 - 2.2e-77 260.5 0.0 2.6e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glycos_transf_1 PF00534.15 CDO72210.1 - 2.3e-24 85.7 0.0 5.4e-24 84.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CDO72210.1 - 5.2e-10 39.5 0.0 2e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.16 CDO72210.1 - 0.00063 18.3 0.0 0.00099 17.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_2 PF13524.1 CDO72210.1 - 0.0073 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Tetraspannin PF00335.15 CDO72212.1 - 2.1e-10 40.2 7.8 2.9e-10 39.8 5.4 1.2 1 0 0 1 1 1 1 Tetraspanin family Herpes_env PF01673.13 CDO72212.1 - 0.24 9.9 0.4 0.37 9.2 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Pyr_redox_2 PF07992.9 CDO72213.1 - 2e-25 89.8 0.0 3.8e-25 88.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO72213.1 - 3.4e-09 36.9 0.3 3e-06 27.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDO72213.1 - 3.9e-06 26.1 0.0 5.4e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 CDO72213.1 - 9.6e-06 24.7 0.1 0.001 18.0 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDO72213.1 - 2e-05 23.6 1.6 0.0017 17.3 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain GIDA PF01134.17 CDO72213.1 - 3.2e-05 22.9 1.1 0.0039 16.1 0.1 3.1 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CDO72213.1 - 0.00065 19.6 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CDO72213.1 - 0.0022 17.1 0.6 0.028 13.5 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CDO72213.1 - 0.018 13.5 0.4 0.04 12.3 0.3 1.6 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 CDO72213.1 - 0.02 13.5 0.0 0.043 12.4 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.14 CDO72213.1 - 0.029 13.4 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FMN_dh PF01070.13 CDO72214.1 - 8.2e-114 380.1 0.0 1e-113 379.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 CDO72214.1 - 0.0017 17.5 0.0 1.2 8.1 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 CDO72214.1 - 0.0038 16.1 0.4 0.014 14.3 0.2 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 CDO72214.1 - 0.031 13.1 0.1 0.05 12.5 0.1 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase FMN_dh PF01070.13 CDO72216.1 - 3e-94 315.8 0.0 3.8e-94 315.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 CDO72216.1 - 0.011 14.7 0.1 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase ThiG PF05690.9 CDO72216.1 - 0.07 12.1 0.7 14 4.6 0.0 3.0 4 0 0 4 4 4 0 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 CDO72216.1 - 0.18 10.6 0.5 0.35 9.7 0.3 1.4 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Dimer_Tnp_hAT PF05699.9 CDO72217.1 - 6.4e-14 51.3 0.0 1e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Glypican PF01153.14 CDO72220.1 - 0.038 12.6 0.2 0.051 12.1 0.1 1.1 1 0 0 1 1 1 0 Glypican Mucin PF01456.12 CDO72223.1 - 2.3 8.0 16.1 2.7 7.7 11.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Urb2 PF10441.4 CDO72223.1 - 2.5 7.6 6.8 2.8 7.4 4.7 1.0 1 0 0 1 1 1 0 Urb2/Npa2 family DUF814 PF05670.8 CDO72224.1 - 6.3e-22 77.2 0.2 1.3e-21 76.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF814) RsgI_N PF12791.2 CDO72224.1 - 0.48 10.1 3.7 0.64 9.7 0.2 2.7 2 1 0 2 2 2 0 Anti-sigma factor N-terminus p450 PF00067.17 CDO72225.1 - 3e-60 204.0 0.0 1.3e-59 201.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 CDO72226.1 - 6.9e-81 271.9 7.0 8e-81 271.7 4.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO72226.1 - 1.1e-07 31.9 4.6 1.3e-07 31.7 1.5 2.2 2 2 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO72226.1 - 1.3e-05 25.6 0.1 0.21 12.1 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 CDO72226.1 - 0.013 15.1 0.1 0.15 11.5 0.1 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal DIOX_N PF14226.1 CDO72227.1 - 5.3e-28 97.8 0.0 8.5e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO72227.1 - 7.1e-07 29.4 0.2 0.011 15.9 0.0 2.6 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily DUF601 PF04642.7 CDO72228.1 - 1.7 7.9 6.9 1.7 7.9 4.6 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF601 PrmA PF06325.8 CDO72229.1 - 7.1e-11 41.7 0.1 1.5e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 CDO72229.1 - 1.4e-09 37.6 0.0 3.3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO72229.1 - 3.4e-09 37.2 0.3 1.2e-08 35.4 0.1 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO72229.1 - 2.5e-08 34.2 0.0 1e-07 32.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO72229.1 - 1.5e-07 31.4 0.0 3.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO72229.1 - 1.8e-06 27.7 0.0 1.6e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CDO72229.1 - 3.5e-06 26.5 0.0 5.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CDO72229.1 - 0.00012 22.4 0.0 0.00034 21.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO72229.1 - 0.00014 22.1 0.0 0.00044 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CDO72229.1 - 0.00017 20.8 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Met_10 PF02475.11 CDO72229.1 - 0.0003 20.4 0.2 0.00049 19.7 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5 PF05185.11 CDO72229.1 - 0.0066 15.4 0.0 0.0096 14.8 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 CDO72229.1 - 0.014 14.1 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.1 CDO72229.1 - 0.022 15.5 0.0 0.061 14.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 CDO72229.1 - 0.025 13.6 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 CDO72229.1 - 0.025 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Vps51 PF08700.6 CDO72229.1 - 0.029 14.1 1.1 0.058 13.2 0.3 1.7 2 0 0 2 2 1 0 Vps51/Vps67 UPF0020 PF01170.13 CDO72229.1 - 0.043 13.3 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 CDO72229.1 - 0.076 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RPAP1_C PF08620.5 CDO72230.1 - 1.2e-19 69.8 0.0 2.5e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 CDO72230.1 - 1.8e-08 33.8 4.7 1.8e-08 33.8 3.3 1.8 2 0 0 2 2 2 1 RPAP1-like, N-terminal DMAP_binding PF06464.6 CDO72230.1 - 0.12 13.0 0.0 0.32 11.6 0.0 1.7 1 0 0 1 1 1 0 DMAP1-binding Domain Remorin_C PF03763.8 CDO72230.1 - 0.3 10.6 3.5 0.66 9.5 2.4 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region Pro-kuma_activ PF09286.6 CDO72232.1 - 6.9e-45 152.6 0.0 1.5e-44 151.5 0.0 1.5 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO72232.1 - 1.8e-05 24.0 0.5 4.8e-05 22.6 0.4 1.6 1 0 0 1 1 1 1 Subtilase family SWI-SNF_Ssr4 PF08549.5 CDO72233.1 - 2.6e-07 29.3 1.8 0.014 13.7 0.0 2.9 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1750) DUF1192 PF06698.6 CDO72233.1 - 0.0082 15.9 0.6 0.015 15.0 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) HIT PF01230.18 CDO72234.1 - 4.2e-25 88.1 0.1 6.4e-25 87.5 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CDO72234.1 - 7.9e-12 45.4 0.4 1.2e-11 44.8 0.2 1.4 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CDO72234.1 - 5.4e-05 22.8 0.2 9.4e-05 22.0 0.2 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pkinase PF00069.20 CDO72235.1 - 1.6e-43 148.7 0.0 2.6e-31 108.7 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO72235.1 - 7.9e-27 93.9 0.0 4.5e-23 81.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CDO72235.1 - 0.0095 15.6 1.4 0.02 14.6 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CDO72235.1 - 0.014 14.2 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 CDO72235.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 CDO72235.1 - 0.022 13.7 0.0 3.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 CDO72235.1 - 0.25 10.4 0.0 0.45 9.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 CDO72236.1 - 3.8e-35 121.2 0.0 1.2e-33 116.3 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 zf-H2C2_5 PF13909.1 CDO72237.1 - 0.00059 19.9 2.3 0.35 11.1 0.0 3.6 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 CDO72237.1 - 0.018 15.3 0.1 0.018 15.3 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 CDO72237.1 - 0.092 12.8 1.8 0.89 9.7 0.5 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 CDO72237.1 - 0.23 11.2 2.9 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 CDO72237.1 - 3.8 8.0 8.7 4.7 7.7 0.1 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Aldo_ket_red PF00248.16 CDO72238.1 - 1.7e-45 155.0 0.0 2.2e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Rho_N PF07498.7 CDO72238.1 - 0.2 11.4 0.2 3.7 7.3 0.0 2.7 3 0 0 3 3 3 0 Rho termination factor, N-terminal domain Pyr_redox_2 PF07992.9 CDO72240.1 - 7.5e-21 74.9 0.0 1.5e-20 73.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO72240.1 - 1.1e-13 51.3 0.1 7.4e-11 42.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CDO72240.1 - 3.2e-10 39.4 1.1 0.0076 15.1 0.0 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CDO72240.1 - 8.3e-10 39.0 0.0 1.3e-07 31.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO72240.1 - 1e-07 31.8 0.6 0.026 14.3 0.0 4.0 3 1 0 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 CDO72240.1 - 1.4e-07 30.4 0.7 0.0065 15.1 0.0 2.4 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 CDO72240.1 - 0.00017 20.6 0.2 0.14 11.0 0.0 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.1 CDO72240.1 - 0.00035 19.6 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 CDO72240.1 - 0.0006 20.0 0.1 0.096 12.9 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding HI0933_like PF03486.9 CDO72240.1 - 0.00076 18.0 0.2 3.2 6.1 0.0 3.8 4 0 0 4 4 4 1 HI0933-like protein GIDA PF01134.17 CDO72240.1 - 0.00087 18.2 4.6 6.3 5.5 0.0 4.4 3 1 2 5 5 5 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CDO72240.1 - 0.0019 18.2 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain StbA PF06406.6 CDO72240.1 - 0.0045 15.9 0.0 0.12 11.3 0.0 2.1 2 0 0 2 2 2 1 StbA protein TrkA_N PF02254.13 CDO72240.1 - 0.0047 16.9 0.1 4.3 7.3 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain FAD_binding_3 PF01494.14 CDO72240.1 - 0.054 12.5 0.6 3 6.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DUF4147 PF13660.1 CDO72240.1 - 0.084 11.9 0.0 6.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Shikimate_DH PF01488.15 CDO72240.1 - 0.12 12.5 0.1 1 9.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RNase_H PF00075.19 CDO72241.1 - 7.1e-14 52.2 0.0 1.2e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO72241.1 - 6.7e-05 23.1 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Proteasome PF00227.21 CDO72242.1 - 1.2e-24 86.7 0.0 2.2e-24 85.7 0.0 1.5 2 0 0 2 2 2 1 Proteasome subunit adh_short PF00106.20 CDO72243.1 - 5.9e-06 26.3 0.6 6.9e-05 22.8 0.1 2.3 1 1 2 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO72243.1 - 0.00018 21.3 0.0 0.0023 17.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Helicase_C PF00271.26 CDO72245.1 - 2.6e-13 49.6 0.0 8.4e-13 47.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Sugar_tr PF00083.19 CDO72247.1 - 6.2e-99 331.6 24.5 7.6e-99 331.3 17.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO72247.1 - 2.7e-17 62.5 35.8 2.7e-17 62.5 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.1 CDO72247.1 - 0.059 13.7 0.2 0.099 13.0 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Con-6 PF10346.4 CDO72249.1 - 3e-33 112.9 5.2 5.5e-16 57.6 0.1 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Toxin_43 PF15604.1 CDO72249.1 - 0.02 14.9 3.3 0.024 14.6 2.3 1.0 1 0 0 1 1 1 0 Putative toxin 43 SpoIIIAH PF12685.2 CDO72249.1 - 0.044 13.2 5.0 0.65 9.4 0.4 2.1 1 1 0 2 2 2 0 SpoIIIAH-like protein DNA_Packaging PF11053.3 CDO72249.1 - 0.1 12.2 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Terminase DNA packaging enzyme LacI PF00356.16 CDO72249.1 - 0.11 12.1 0.6 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF3359 PF11839.3 CDO72249.1 - 0.71 10.2 3.4 6.9 7.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3359) ERCC4 PF02732.10 CDO72250.1 - 1.8e-28 99.0 0.0 1.7e-27 95.8 0.0 2.3 2 0 0 2 2 2 1 ERCC4 domain zf-H2C2_2 PF13465.1 CDO72252.1 - 3.1 8.2 13.3 28 5.2 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double domain Rot1 PF10681.4 CDO72253.1 - 2.1e-53 180.8 0.2 2.5e-53 180.5 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Glycos_transf_3 PF00591.16 CDO72254.1 - 2.6e-09 36.8 1.0 3.8e-09 36.3 0.7 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 CDO72254.1 - 6.8e-05 22.3 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Glycos_transf_3 PF00591.16 CDO72255.1 - 2.3e-14 53.3 2.6 3.3e-14 52.9 1.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 CDO72255.1 - 1.8e-05 24.2 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DRY_EERY PF09750.4 CDO72256.1 - 0.078 13.0 0.2 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Alternative splicing regulator adh_short PF00106.20 CDO72258.1 - 8.1e-20 71.4 0.0 1.6e-19 70.4 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CDO72258.1 - 9.6e-09 35.1 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CDO72258.1 - 8.3e-06 25.7 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CDO72258.1 - 8e-05 22.7 0.1 0.00076 19.5 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CDO72258.1 - 0.0028 17.1 0.1 0.0061 16.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 CDO72258.1 - 0.0061 15.5 0.1 0.01 14.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 CDO72258.1 - 0.039 14.0 0.1 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CDO72258.1 - 0.065 13.4 0.1 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Clat_adaptor_s PF01217.15 CDO72259.1 - 6.1e-57 191.3 2.9 6.7e-57 191.1 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UTP15_C PF09384.5 CDO72259.1 - 0.1 12.3 0.4 7 6.3 0.0 2.2 1 1 1 2 2 2 0 UTP15 C terminal Gpi16 PF04113.9 CDO72260.1 - 2.2e-91 306.5 0.3 5.4e-43 146.8 0.1 3.0 2 1 0 3 3 3 3 Gpi16 subunit, GPI transamidase component AAA PF00004.24 CDO72261.1 - 2.1e-87 290.0 0.0 1.7e-42 144.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDO72261.1 - 2.9e-13 49.7 0.0 2e-07 30.7 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDO72261.1 - 4.6e-12 46.3 0.5 0.00017 21.6 0.1 3.6 2 1 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 CDO72261.1 - 2.3e-11 43.1 0.0 0.00029 19.9 0.0 3.3 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CDO72261.1 - 5.7e-09 36.1 0.0 0.00066 19.8 0.0 4.2 2 2 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CDO72261.1 - 7.6e-09 35.6 0.0 0.0013 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CDO72261.1 - 6e-08 32.3 2.0 3.9e-05 23.3 0.1 3.6 3 1 0 3 3 3 1 Part of AAA domain AAA_33 PF13671.1 CDO72261.1 - 3.9e-07 30.0 0.0 0.00011 22.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CDO72261.1 - 4.5e-07 29.4 0.0 0.00018 20.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 CDO72261.1 - 6.7e-07 29.2 0.0 0.0095 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CDO72261.1 - 1.7e-06 27.3 0.0 0.00046 19.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 CDO72261.1 - 9e-06 25.2 2.2 0.11 11.9 0.0 4.2 2 2 2 4 4 4 1 AAA domain TIP49 PF06068.8 CDO72261.1 - 1.2e-05 24.2 0.0 0.0081 14.9 0.0 2.6 3 0 0 3 3 3 2 TIP49 C-terminus AAA_17 PF13207.1 CDO72261.1 - 1.7e-05 25.5 0.0 0.00052 20.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CDO72261.1 - 8.6e-05 22.2 0.0 0.1 12.2 0.0 4.0 3 1 0 4 4 4 1 NACHT domain Sigma54_activ_2 PF14532.1 CDO72261.1 - 0.00011 22.2 0.0 0.097 12.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 CDO72261.1 - 0.00022 21.3 0.0 0.09 12.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 CDO72261.1 - 0.00049 20.1 0.0 0.07 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CDO72261.1 - 0.00072 18.7 0.2 0.26 10.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 CDO72261.1 - 0.0012 18.5 0.0 0.55 9.8 0.0 3.5 4 0 0 4 4 4 1 Bacterial dnaA protein AAA_3 PF07726.6 CDO72261.1 - 0.0015 18.1 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 CDO72261.1 - 0.0017 17.9 0.0 0.029 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CDO72261.1 - 0.0053 16.3 0.0 0.73 9.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DAP3 PF10236.4 CDO72261.1 - 0.0064 15.4 0.0 0.017 14.0 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Sigma54_activat PF00158.21 CDO72261.1 - 0.013 14.9 0.0 0.6 9.5 0.0 3.1 2 1 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 CDO72261.1 - 0.015 14.5 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 CDO72261.1 - 0.016 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CDO72261.1 - 0.017 14.6 0.0 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 CDO72261.1 - 0.02 15.1 0.0 0.37 11.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.8 CDO72261.1 - 0.023 13.5 0.0 3.5 6.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CDO72261.1 - 0.024 14.3 0.0 31 4.1 0.0 3.6 2 2 2 4 4 4 0 Archaeal ATPase KaiC PF06745.8 CDO72261.1 - 0.039 13.0 0.0 3.7 6.5 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.1 CDO72261.1 - 0.039 13.5 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 CDO72261.1 - 0.075 11.8 0.0 0.63 8.7 0.0 2.2 3 0 0 3 3 2 0 AFG1-like ATPase ATP-synt_ab PF00006.20 CDO72261.1 - 0.076 12.4 0.0 0.19 11.2 0.0 1.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 CDO72261.1 - 0.083 12.4 0.1 4.1 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 CDO72261.1 - 0.091 11.4 0.0 0.44 9.1 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 CDO72261.1 - 0.098 11.5 0.0 0.24 10.2 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 CDO72261.1 - 0.15 11.7 0.1 1.9 8.1 0.0 2.6 2 2 1 3 3 2 0 NTPase adh_short PF00106.20 CDO72262.1 - 1.5e-23 83.5 0.0 2.4e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO72262.1 - 1.2e-21 77.5 0.1 4.8e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO72262.1 - 8.5e-08 32.0 0.1 1.7e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CDO72262.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Coprogen_oxidas PF01218.13 CDO72263.1 - 5.8e-116 386.1 0.0 9.6e-116 385.4 0.0 1.4 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF876 PF05936.7 CDO72263.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) PLAC8 PF04749.12 CDO72264.1 - 0.046 14.2 0.1 0.078 13.5 0.1 1.3 1 0 0 1 1 1 0 PLAC8 family Lactamase_B PF00753.22 CDO72265.1 - 4.2e-09 36.3 2.3 7.2e-09 35.5 1.6 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CDO72265.1 - 3.4e-05 23.4 0.1 9.5e-05 22.0 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ArfGap PF01412.13 CDO72266.1 - 3.9e-14 52.4 0.1 8.9e-14 51.2 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Glyco_hydro_12 PF01670.11 CDO72267.1 - 1.1e-31 109.7 1.7 1.1e-31 109.7 1.2 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Glyco_hydro_12 PF01670.11 CDO72268.1 - 1e-24 87.0 2.8 1.7e-24 86.3 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 PLRV_ORF5 PF01690.12 CDO72268.1 - 0.12 11.4 9.6 0.2 10.7 6.6 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF605 PF04652.11 CDO72268.1 - 0.13 11.6 4.9 0.17 11.2 3.4 1.2 1 0 0 1 1 1 0 Vta1 like Lamp PF01299.12 CDO72268.1 - 3.5 6.6 9.7 0.96 8.5 4.7 1.5 1 1 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DDE_3 PF13358.1 CDO72269.1 - 6.1e-22 77.9 0.0 9.2e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CDO72269.1 - 6.3e-07 29.3 0.3 0.00051 20.0 0.1 2.8 2 0 0 2 2 2 2 Transposase HTH_23 PF13384.1 CDO72269.1 - 7.3e-05 22.2 0.0 0.00051 19.5 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 CDO72269.1 - 9.1e-05 21.9 0.0 0.00022 20.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.1 CDO72269.1 - 0.00018 21.4 0.0 0.002 18.0 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 CDO72269.1 - 0.0002 20.5 0.0 0.00043 19.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 rve PF00665.21 CDO72269.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_11 PF08279.7 CDO72269.1 - 0.0032 17.0 0.0 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 HTH domain HTH_IclR PF09339.5 CDO72269.1 - 0.01 15.4 0.1 0.03 13.9 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain GntR PF00392.16 CDO72269.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_29 PF13551.1 CDO72269.1 - 0.021 14.9 0.1 0.05 13.7 0.1 1.8 1 1 0 1 1 1 0 Winged helix-turn helix UPF0122 PF04297.9 CDO72269.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like MarR_2 PF12802.2 CDO72269.1 - 0.13 11.9 0.0 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 MarR family HTH_AraC PF00165.18 CDO72269.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Acetyltransf_1 PF00583.19 CDO72270.1 - 2.3e-10 40.3 0.0 3.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDO72270.1 - 1.9e-08 34.3 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDO72270.1 - 4.5e-08 33.2 0.0 6.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CDO72270.1 - 0.0025 17.6 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 CDO72270.1 - 0.016 15.0 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CDO72270.1 - 0.07 13.2 0.0 0.092 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UQ_con PF00179.21 CDO72271.1 - 4.8e-42 142.7 0.0 5.9e-42 142.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 CDO72271.1 - 1.8e-20 72.2 0.4 3.1e-20 71.5 0.3 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 CDO72271.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B TPP_enzyme_N PF02776.13 CDO72272.1 - 3.2e-36 124.4 1.5 2.7e-33 114.8 0.4 2.7 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CDO72272.1 - 3.3e-16 59.2 1.4 6.5e-16 58.2 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CDO72272.1 - 7.8e-12 45.1 0.1 5.7e-11 42.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain NAGidase PF07555.8 CDO72272.1 - 0.063 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase TPP_enzyme_N PF02776.13 CDO72273.1 - 5.3e-24 84.6 3.6 3e-21 75.6 1.3 3.0 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CDO72273.1 - 9.4e-20 70.7 0.0 1.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CDO72273.1 - 5.6e-16 58.5 0.0 3.8e-15 55.8 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Rick_17kDa_Anti PF05433.10 CDO72273.1 - 0.0017 17.9 4.0 0.0041 16.7 0.8 2.6 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 CDO72273.1 - 0.023 14.3 1.2 0.023 14.3 0.8 2.8 2 1 1 3 3 3 0 Glycine zipper DXP_synthase_N PF13292.1 CDO72273.1 - 0.025 13.5 0.3 0.2 10.5 0.0 2.3 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase F-box-like PF12937.2 CDO72274.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like DNA_ligase_A_C PF04679.10 CDO72274.1 - 0.1 12.9 0.0 12 6.3 0.0 3.4 2 1 1 3 3 3 0 ATP dependent DNA ligase C terminal region adh_short PF00106.20 CDO72275.1 - 5.5e-25 88.2 0.2 7e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO72275.1 - 3.7e-13 49.7 0.0 5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO72275.1 - 3e-10 40.0 0.1 5.1e-10 39.3 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO72275.1 - 3e-06 26.8 0.0 6.7e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CDO72275.1 - 0.0013 17.6 0.1 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CDO72275.1 - 0.0035 17.3 0.1 0.0074 16.3 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CDO72276.1 - 9.9e-24 84.1 0.8 1.4e-23 83.5 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO72276.1 - 9.4e-13 48.4 0.0 1.3e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO72276.1 - 1.2e-10 41.2 0.1 2.2e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CDO72276.1 - 0.00058 19.9 0.3 0.0011 19.0 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CDO72276.1 - 0.013 14.3 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_35 PF01301.14 CDO72277.1 - 6e-58 196.6 0.0 4.5e-56 190.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 CDO72277.1 - 8.8e-49 164.4 7.3 1.6e-25 89.4 0.3 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 CDO72277.1 - 5.2e-36 123.7 1.9 9.4e-36 122.8 1.3 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 CDO72277.1 - 2e-17 62.3 0.4 7.3e-17 60.5 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 CDO72277.1 - 0.0032 16.6 0.0 0.027 13.5 0.0 2.1 1 1 0 1 1 1 1 Beta-galactosidase adh_short_C2 PF13561.1 CDO72279.1 - 7.5e-05 22.6 0.0 0.00023 21.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_15 PF00723.16 CDO72280.1 - 1.9e-26 92.6 0.0 3.6e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 His_Phos_2 PF00328.17 CDO72281.1 - 1.9e-37 129.3 0.0 3.1e-29 102.4 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Gemini_mov PF01708.11 CDO72281.1 - 0.18 11.4 0.2 0.32 10.5 0.2 1.4 1 0 0 1 1 1 0 Geminivirus putative movement protein Lar_restr_allev PF14354.1 CDO72282.1 - 0.004 17.4 3.0 0.018 15.3 1.0 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar EHN PF06441.7 CDO72283.1 - 1.6e-20 73.1 0.0 2.9e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CDO72283.1 - 0.076 12.8 0.1 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.11 CDO72284.1 - 1e-26 93.5 47.9 1.5e-26 93.0 33.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 CDO72285.1 - 1.4e-10 40.4 37.4 4e-06 25.7 13.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDO72285.1 - 0.00017 20.1 10.7 0.00017 20.1 7.4 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 CDO72285.1 - 0.0024 16.5 4.0 0.0024 16.5 2.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Herpes_gE PF02480.11 CDO72286.1 - 0.0081 14.4 0.0 0.0098 14.1 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E CBM_6 PF03422.10 CDO72286.1 - 0.032 14.3 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) Alpha_GJ PF03229.8 CDO72286.1 - 0.033 14.5 0.1 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF2759 PF10958.3 CDO72286.1 - 1.1 8.9 4.8 3.1 7.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) PDGLE PF13190.1 CDO72287.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 PDGLE domain Herpes_gE PF02480.11 CDO72287.1 - 0.03 12.5 0.0 0.047 11.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Gram_pos_anchor PF00746.16 CDO72287.1 - 0.18 11.6 1.7 0.37 10.6 1.2 1.6 1 0 0 1 1 1 0 Gram positive anchor SKG6 PF08693.5 CDO72287.1 - 0.57 9.5 8.3 1.3 8.4 5.3 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain EB1 PF03271.12 CDO72288.1 - 2.8e-17 62.4 0.7 6e-17 61.4 0.5 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 CDO72288.1 - 5.4e-07 29.6 0.5 9.8e-07 28.7 0.4 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Suppressor_APC PF11414.3 CDO72288.1 - 0.078 12.7 0.8 0.21 11.4 0.6 1.7 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein F-box-like PF12937.2 CDO72289.1 - 3.7e-06 26.5 0.4 8.9e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 F-box-like Chitin_synth_1 PF01644.12 CDO72291.1 - 5.6e-88 292.8 0.1 8.7e-88 292.2 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CDO72291.1 - 1.1e-31 108.3 0.1 2.1e-31 107.4 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CDO72291.1 - 7.4e-24 84.0 0.3 1.1e-17 63.6 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 CDO72291.1 - 4.4e-06 26.6 0.0 1.1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CDO72291.1 - 0.00014 21.6 12.5 0.0013 18.4 8.7 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 AA_permease PF00324.16 CDO72292.1 - 7.5e-78 261.9 33.8 3.6e-73 246.5 11.0 3.0 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 CDO72292.1 - 1.6e-32 112.5 17.6 4e-32 111.2 12.2 1.6 1 1 0 1 1 1 1 Amino acid permease WBP-1 PF11669.3 CDO72293.1 - 0.053 13.6 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF754 PF05449.6 CDO72293.1 - 0.38 10.7 7.0 0.58 10.2 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF754) Tic20 PF09685.5 CDO72293.1 - 7.4 6.6 10.4 0.51 10.3 0.3 2.7 3 0 0 3 3 3 0 Tic20-like protein MFS_1 PF07690.11 CDO72294.1 - 3.2e-27 95.1 60.0 4.1e-21 75.1 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_35 PF01301.14 CDO72295.1 - 2.8e-60 204.3 1.3 4.4e-60 203.6 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 CDO72295.1 - 2.2e-41 140.5 0.2 8.7e-23 80.7 0.0 3.2 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 CDO72295.1 - 8.1e-33 113.3 0.3 1.3e-32 112.5 0.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 CDO72295.1 - 9.6e-19 66.5 0.1 2.3e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 CDO72295.1 - 0.0033 16.5 0.1 0.017 14.2 0.0 1.9 1 1 0 1 1 1 1 Beta-galactosidase adh_short PF00106.20 CDO72296.1 - 2.2e-30 105.7 0.3 2.6e-30 105.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO72296.1 - 4.4e-16 59.3 0.0 5.4e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO72296.1 - 2.3e-15 56.6 0.2 3.9e-15 55.9 0.2 1.3 1 0 0 1 1 1 1 KR domain HD_4 PF13328.1 CDO72296.1 - 0.035 13.8 0.1 0.052 13.2 0.1 1.2 1 0 0 1 1 1 0 HD domain Epimerase PF01370.16 CDO72296.1 - 0.09 12.1 0.2 0.15 11.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 CDO72297.1 - 2.1e-64 217.7 0.0 4.2e-62 210.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF2499 PF10693.4 CDO72297.1 - 0.025 14.6 1.5 0.07 13.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) DUF4218 PF13960.1 CDO72299.1 - 2.6e-06 26.8 0.1 4.9e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 CDO72299.1 - 0.017 14.2 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Transposase family tnp2 DUF3510 PF12022.3 CDO72300.1 - 0.22 11.6 1.2 6.6 6.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DSPc PF00782.15 CDO72301.1 - 1.3e-30 105.7 0.0 1.5e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 CDO72301.1 - 3.4e-05 22.9 0.0 3.7e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 CDO72301.1 - 0.0032 17.5 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CDO72301.1 - 0.0049 16.2 0.0 0.0063 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Complex1_51K PF01512.12 CDO72302.1 - 2.1e-48 163.8 0.0 3.1e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CDO72302.1 - 3e-21 74.3 2.6 3.1e-21 74.2 0.3 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CDO72302.1 - 3.5e-08 33.2 0.0 9.5e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 SLBB domain DUF4611 PF15387.1 CDO72303.1 - 0.52 10.4 2.9 9.4 6.4 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Dimer_Tnp_hAT PF05699.9 CDO72304.1 - 2e-17 62.5 0.0 5e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AA_permease PF00324.16 CDO72305.1 - 2.3e-128 428.5 36.9 2.8e-128 428.2 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CDO72305.1 - 6e-35 120.6 40.4 7.1e-35 120.3 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease BNR PF02012.15 CDO72307.1 - 1.7e-15 54.2 31.0 0.15 12.0 0.0 10.4 9 0 0 9 9 9 7 BNR/Asp-box repeat CBM_1 PF00734.13 CDO72307.1 - 6.9e-14 51.2 10.2 2.2e-13 49.5 7.1 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain LRR_6 PF13516.1 CDO72308.1 - 8.4e-11 40.7 4.1 0.14 12.3 0.0 8.3 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.2 CDO72308.1 - 1.4e-09 37.3 21.6 0.0015 18.1 0.0 7.6 7 3 1 9 9 9 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO72308.1 - 7.1e-08 32.0 15.0 0.28 10.9 0.3 6.6 4 3 2 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 CDO72308.1 - 0.013 15.4 12.6 22 5.6 0.1 7.8 8 2 0 8 8 8 0 Leucine Rich Repeat LRR_7 PF13504.1 CDO72308.1 - 0.2 12.0 13.4 32 5.3 0.0 7.8 8 1 0 8 8 8 0 Leucine rich repeat DUF846 PF05832.7 CDO72311.1 - 5.8e-25 87.6 16.6 6.2e-14 51.8 1.9 2.8 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF846) DSPc PF00782.15 CDO72312.1 - 2.7e-21 75.5 0.0 1.5e-19 69.9 0.0 2.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDO72312.1 - 0.00097 18.5 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FAD_binding_6 PF00970.19 CDO72313.1 - 9.1e-32 109.1 0.0 1.5e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CDO72313.1 - 7.5e-30 103.7 0.0 1.1e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CDO72313.1 - 1.1e-06 28.6 0.0 0.0002 21.3 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CDO72313.1 - 0.00037 20.4 0.0 0.00072 19.5 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain GST_N_3 PF13417.1 CDO72315.1 - 1e-07 32.0 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO72315.1 - 0.00076 19.3 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CDO72315.1 - 0.037 14.0 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CAP PF00188.21 CDO72316.1 - 6.1e-22 78.4 0.5 6.1e-22 78.4 0.4 2.2 2 0 0 2 2 2 1 Cysteine-rich secretory protein family HAMP PF00672.20 CDO72316.1 - 0.12 12.5 0.1 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 HAMP domain MTD PF01993.13 CDO72317.1 - 0.07 12.1 0.0 0.086 11.8 0.0 1.1 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase DUF2012 PF09430.5 CDO72318.1 - 4.3e-11 42.7 0.0 7.1e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2012) Fcf1 PF04900.7 CDO72319.1 - 9.2e-28 96.3 0.2 1.7e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 Fcf1 DUF1754 PF08555.5 CDO72319.1 - 1.7 9.2 12.4 2.9 8.5 8.6 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) WD40 PF00400.27 CDO72320.1 - 1.2e-68 224.6 18.4 7.4e-13 47.8 0.3 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CDO72320.1 - 3.8e-13 49.5 0.1 4.5e-06 26.5 0.0 3.9 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CDO72320.1 - 1.4e-07 30.0 10.2 0.068 11.3 0.3 5.5 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 CDO72320.1 - 0.0011 17.8 0.0 0.034 12.9 0.0 2.6 1 1 2 3 3 3 1 Coatomer WD associated region DUF1513 PF07433.6 CDO72320.1 - 0.011 14.7 0.0 0.54 9.1 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) IKI3 PF04762.7 CDO72320.1 - 0.016 13.0 0.2 0.43 8.3 0.1 2.6 2 1 1 3 3 3 0 IKI3 family SAC3_GANP PF03399.11 CDO72321.1 - 9.1e-23 80.8 0.0 1.4e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CDO72321.1 - 2.2e-22 79.3 0.0 3.8e-22 78.5 0.0 1.4 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 Aa_trans PF01490.13 CDO72322.1 - 9.3e-56 189.0 13.0 1.2e-55 188.6 9.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CDO72322.1 - 0.00016 20.6 6.6 0.00028 19.8 4.5 1.4 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF2107 PF09880.4 CDO72322.1 - 2.6 7.9 10.2 0.91 9.4 0.1 3.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2107) Abhydro_lipase PF04083.11 CDO72323.1 - 1.2e-22 79.0 0.3 2.1e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 CDO72323.1 - 3e-08 33.4 0.0 1.1e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO72323.1 - 3.8e-05 23.4 0.0 6.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO72323.1 - 0.0015 18.4 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family WHIM3 PF15614.1 CDO72324.1 - 7.2e-06 25.6 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WAC_Acf1_DNA_bd PF10537.4 CDO72325.1 - 7.2e-32 109.5 1.9 5.7e-26 90.6 0.4 2.8 2 0 0 2 2 2 2 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CDO72325.1 - 9e-13 47.7 0.0 2.5e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.1 CDO72325.1 - 7.2e-06 25.6 0.1 1.9e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Spore_III_AF PF09581.5 CDO72325.1 - 1.4 8.7 7.4 0.27 11.0 1.7 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) GFO_IDH_MocA PF01408.17 CDO72327.1 - 5.2e-10 39.8 0.1 9.5e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CDO72327.1 - 0.012 15.4 0.3 0.076 12.8 0.2 2.2 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Saccharop_dh PF03435.13 CDO72327.1 - 0.051 12.5 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Cyclin_N PF00134.18 CDO72328.1 - 2.1e-37 127.5 0.6 4e-37 126.6 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CDO72328.1 - 4.6e-08 33.0 0.1 1.2e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain RdRP PF05183.7 CDO72330.1 - 3.1e-157 524.7 0.0 4.7e-157 524.1 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase LSM PF01423.17 CDO72331.1 - 3.3e-11 42.5 0.1 4.8e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain Pescadillo_N PF06732.6 CDO72332.1 - 1.3e-117 392.1 0.0 1.3e-117 392.1 0.0 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 CDO72332.1 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF853 PF05872.7 CDO72332.1 - 7.9 4.7 10.9 12 4.0 7.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Sec7 PF01369.15 CDO72333.1 - 6.3e-40 136.8 0.0 1.1e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 CDO72333.1 - 6.7e-13 48.8 0.0 1.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CDO72333.1 - 3.2e-09 36.9 0.2 8.2e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 PH domain DUF4520 PF15016.1 CDO72333.1 - 0.024 14.2 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) PDEase_I PF00233.14 CDO72333.1 - 0.44 10.2 0.6 0.71 9.5 0.4 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Con-6 PF10346.4 CDO72336.1 - 8.4e-24 82.6 9.5 9.3e-13 47.3 0.9 2.0 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 CDO72336.1 - 0.031 13.7 2.5 0.14 11.6 0.2 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein RNA_pol_Rpc82 PF05645.8 CDO72336.1 - 0.24 10.9 2.2 0.31 10.5 1.5 1.3 1 1 0 1 1 1 0 RNA polymerase III subunit RPC82 MARVEL PF01284.18 CDO72337.1 - 0.3 10.8 21.5 0.47 10.2 14.9 1.3 1 0 0 1 1 1 0 Membrane-associating domain Con-6 PF10346.4 CDO72338.1 - 6.5e-31 105.4 7.3 9.6e-16 56.9 0.3 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 CDO72338.1 - 0.001 18.6 2.2 0.0079 15.7 0.5 2.0 1 1 1 2 2 2 2 SpoIIIAH-like protein TTL PF03133.10 CDO72339.1 - 4.7e-42 143.9 0.0 6.5e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family RNA_pol_Rpb8 PF03870.10 CDO72339.1 - 6e-39 133.3 0.0 9.5e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb8 ATP-grasp_4 PF13535.1 CDO72339.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DUF2404 PF10296.4 CDO72340.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Nucleoporin_C PF03177.9 CDO72341.1 - 1.8e-78 264.5 0.8 2.7e-78 263.9 0.5 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CDO72341.1 - 5.5e-62 209.8 0.0 7.9e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.20 CDO72342.1 - 8.7e-69 231.5 0.0 1e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO72342.1 - 2.7e-26 92.1 0.0 5.6e-26 91.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO72342.1 - 3.5e-07 29.4 0.1 1.1e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CDO72342.1 - 0.0033 16.7 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Myb_DNA-bind_2 PF08914.6 CDO72343.1 - 3.1e-10 39.7 1.3 8.1e-10 38.3 0.9 1.8 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 CDO72343.1 - 0.024 15.1 2.6 0.23 12.0 1.7 2.5 2 1 0 2 2 2 0 Rap1, DNA-binding Cytochrome_CBB3 PF13442.1 CDO72343.1 - 0.1 12.7 0.4 15 5.8 0.1 2.8 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III FAD-oxidase_C PF02913.14 CDO72344.1 - 1.3e-58 198.2 0.1 1.9e-58 197.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CDO72344.1 - 5e-34 116.7 0.4 9.7e-34 115.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Methyltransf_14 PF08484.6 CDO72344.1 - 0.0041 16.6 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain LEM PF03020.10 CDO72345.1 - 0.26 10.7 1.5 0.71 9.3 0.1 2.1 2 0 0 2 2 2 0 LEM domain WD40 PF00400.27 CDO72346.1 - 3.9e-15 55.0 5.8 1e-05 25.2 0.0 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat Endonuc-dimeris PF09124.5 CDO72347.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation DUF3518 PF12031.3 CDO72348.1 - 0.0004 19.2 0.0 0.00065 18.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3518) DUF1764 PF08576.5 CDO72349.1 - 2.5e-18 66.7 1.2 2.5e-18 66.7 0.9 2.1 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) NST1 PF13945.1 CDO72349.1 - 5.1 7.1 7.5 6.2 6.8 5.1 1.3 1 1 0 1 1 1 0 Salt tolerance down-regulator BLVR PF06375.6 CDO72349.1 - 7.8 6.3 13.3 1.6 8.5 6.9 1.4 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Ras PF00071.17 CDO72351.1 - 1.9e-55 186.6 0.0 2.3e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO72351.1 - 1.6e-18 67.3 0.0 2.5e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO72351.1 - 6.2e-15 54.8 0.0 2.7e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO72351.1 - 7.1e-08 31.8 0.0 8.1e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDO72351.1 - 9.2e-06 25.2 0.0 1.5e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDO72351.1 - 0.00035 20.5 0.0 0.00081 19.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Alginate_lyase PF05426.7 CDO72352.1 - 5.6e-56 189.8 4.0 2.4e-53 181.2 1.2 2.3 2 0 0 2 2 2 2 Alginate lyase AAA_18 PF13238.1 CDO72354.1 - 1.2e-28 100.0 0.0 1.8e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDO72354.1 - 1.4e-16 61.3 0.1 2.9e-16 60.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CDO72354.1 - 1.3e-06 28.6 0.0 2.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CDO72354.1 - 6.9e-05 22.8 0.0 0.00018 21.4 0.0 1.9 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 CDO72354.1 - 7.6e-05 22.6 0.0 0.00053 19.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO72354.1 - 0.00013 21.6 0.4 0.00025 20.7 0.3 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CDO72354.1 - 0.0002 21.5 0.0 0.00035 20.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 CDO72354.1 - 0.00029 20.7 0.0 0.0062 16.4 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase SKI PF01202.17 CDO72354.1 - 0.0007 19.4 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 Shikimate kinase KTI12 PF08433.5 CDO72354.1 - 0.0022 17.2 0.0 0.0041 16.3 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Cytidylate_kin2 PF13189.1 CDO72354.1 - 0.0049 16.7 0.0 0.031 14.2 0.0 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family Zeta_toxin PF06414.7 CDO72354.1 - 0.0064 15.6 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin KaiC PF06745.8 CDO72354.1 - 0.0066 15.5 0.3 0.28 10.2 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_14 PF13173.1 CDO72354.1 - 0.0096 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CDO72354.1 - 0.014 15.1 0.1 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 CDO72354.1 - 0.017 14.2 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 CDO72354.1 - 0.033 13.1 0.0 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 CDO72354.1 - 0.04 13.6 0.8 0.2 11.3 0.1 2.1 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.1 CDO72354.1 - 0.041 13.8 0.1 0.092 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 CDO72354.1 - 0.054 13.0 0.3 0.12 11.9 0.1 1.5 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CDO72354.1 - 0.07 11.9 0.6 0.12 11.1 0.1 1.6 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 CDO72354.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 CDO72354.1 - 0.11 11.9 0.1 0.52 9.7 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.12 CDO72354.1 - 0.11 11.9 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase T2SE PF00437.15 CDO72354.1 - 0.11 11.3 1.1 0.17 10.7 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 CDO72354.1 - 0.15 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 CDO72354.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ELL PF10390.4 CDO72354.1 - 0.16 11.1 0.2 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL PAPA-1 PF04795.7 CDO72357.1 - 8.8e-15 55.1 8.1 8.8e-15 55.1 5.6 2.7 3 1 0 3 3 3 1 PAPA-1-like conserved region PBP1_TM PF14812.1 CDO72357.1 - 0.025 14.8 2.5 0.025 14.8 1.7 4.6 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cyclin_N PF00134.18 CDO72359.1 - 1.7e-11 43.7 0.2 4.7e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 CDO72359.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat POPLD PF08170.7 CDO72359.1 - 0.023 14.5 0.3 0.054 13.3 0.2 1.6 1 0 0 1 1 1 0 POPLD (NUC188) domain GYF PF02213.11 CDO72360.1 - 8e-13 47.7 0.0 1.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 GYF domain Amidohydro_4 PF13147.1 CDO72361.1 - 4.5e-20 72.8 6.0 1.8e-18 67.5 0.3 4.1 2 2 1 4 4 4 1 Amidohydrolase Amidohydro_5 PF13594.1 CDO72361.1 - 8.1e-13 48.0 0.4 2.3e-08 33.7 0.0 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 CDO72361.1 - 2.4e-10 40.6 0.2 7.5e-08 32.3 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 CDO72361.1 - 6.1e-08 32.2 0.8 1.9e-06 27.3 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase family zf-C2H2 PF00096.21 CDO72362.1 - 9e-14 50.8 16.6 0.0054 17.0 0.1 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO72362.1 - 9.2e-10 38.1 15.8 0.02 15.2 0.2 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 CDO72362.1 - 0.029 14.5 0.8 21 5.4 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CDO72362.1 - 0.049 13.8 0.0 0.049 13.8 0.0 4.1 4 1 0 4 4 4 0 C2H2-type zinc-finger domain DUF3505 PF12013.3 CDO72362.1 - 1.1 9.5 6.2 0.43 10.8 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3505) zf-C2H2_jaz PF12171.3 CDO72362.1 - 2.6 8.3 9.1 12 6.1 0.5 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Sin_N PF04801.8 CDO72363.1 - 3e-20 72.4 0.1 4.5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Sin-like protein conserved region LIM PF00412.17 CDO72364.1 - 0.00021 21.2 19.7 0.0053 16.7 2.4 3.8 4 1 0 4 4 4 2 LIM domain Acyl-CoA_dh_M PF02770.14 CDO72365.1 - 0.064 12.7 0.1 0.18 11.3 0.1 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain DnaJ PF00226.26 CDO72368.1 - 1.5e-19 69.5 0.4 2.4e-19 68.8 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 CDO72368.1 - 0.086 12.8 2.1 0.14 12.2 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Rick_17kDa_Anti PF05433.10 CDO72368.1 - 0.69 9.6 0.1 0.69 9.6 0.0 3.0 3 0 0 3 3 3 0 Glycine zipper 2TM domain ATPase_gene1 PF09527.5 CDO72368.1 - 2.4 8.0 8.1 1.3 8.9 2.5 2.2 1 1 1 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) BPD_transp_2 PF02653.11 CDO72369.1 - 7.1 5.4 21.5 9.4e+02 -1.5 14.9 2.1 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component Formyl_trans_N PF00551.14 CDO72370.1 - 4.3e-38 130.6 0.0 2.1e-19 69.7 0.0 2.0 2 0 0 2 2 2 2 Formyl transferase MannoseP_isomer PF01050.13 CDO72370.1 - 0.033 13.7 0.1 0.053 13.1 0.1 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Cyt-b5 PF00173.23 CDO72371.1 - 4.8e-24 83.9 0.0 7.1e-24 83.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SAP PF02037.22 CDO72372.1 - 0.019 14.4 0.2 0.042 13.3 0.2 1.6 1 0 0 1 1 1 0 SAP domain DivIC PF04977.10 CDO72372.1 - 0.048 13.1 1.0 0.096 12.1 0.7 1.5 1 0 0 1 1 1 0 Septum formation initiator ADIP PF11559.3 CDO72372.1 - 0.059 13.2 1.1 0.1 12.4 0.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Rho_N PF07498.7 CDO72372.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain HALZ PF02183.13 CDO72372.1 - 0.26 11.0 1.4 1.4 8.7 0.0 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper Pkinase PF00069.20 CDO72373.1 - 6.4e-61 205.7 0.0 2.7e-60 203.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO72373.1 - 8.5e-26 90.5 0.0 1.1e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO72373.1 - 0.00012 21.1 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDO72373.1 - 0.011 14.8 0.1 0.019 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDO72373.1 - 0.034 13.8 0.6 0.091 12.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family S_100 PF01023.14 CDO72373.1 - 0.084 12.2 1.1 0.26 10.6 0.5 2.0 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain RIO1 PF01163.17 CDO72373.1 - 0.11 11.7 0.1 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Cupredoxin_1 PF13473.1 CDO72374.1 - 0.044 13.6 0.2 0.36 10.7 0.1 2.5 3 0 0 3 3 3 0 Cupredoxin-like domain DKCLD PF08068.7 CDO72375.1 - 1.9e-30 104.5 0.0 1.1e-29 102.1 0.0 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 CDO72375.1 - 3.8e-22 79.0 0.2 1.4e-18 67.5 0.1 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CDO72375.1 - 4.5e-21 74.3 0.9 8.7e-21 73.4 0.6 1.5 1 0 0 1 1 1 1 PUA domain Ribosomal_L22e PF01776.12 CDO72376.1 - 7.4e-49 164.4 0.7 9.4e-49 164.0 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AdoMet_Synthase PF01941.14 CDO72376.1 - 0.049 12.1 0.0 0.05 12.0 0.0 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) HA2 PF04408.18 CDO72377.1 - 5.6e-18 64.8 0.0 2.4e-17 62.8 0.0 2.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CDO72377.1 - 8.3e-13 48.0 0.3 1.8e-12 46.9 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CDO72377.1 - 1.2e-09 37.9 0.0 3.3e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CDO72377.1 - 2.1e-07 31.1 0.0 5.5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CDO72377.1 - 1.2e-05 24.8 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.22 CDO72377.1 - 0.081 13.2 0.0 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 CDO72377.1 - 0.082 11.7 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 CDO72377.1 - 0.2 11.2 0.0 0.53 9.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Herpes_BLLF1 PF05109.8 CDO72377.1 - 0.38 8.6 1.1 0.61 7.9 0.8 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SNF2_N PF00176.18 CDO72378.1 - 2.4e-72 243.2 2.1 3.8e-72 242.6 1.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 CDO72378.1 - 2e-49 167.2 19.4 2e-49 167.2 13.5 2.2 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.26 CDO72378.1 - 1.1e-12 47.5 0.0 2.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CDO72378.1 - 4.4e-07 29.0 0.1 1.8e-05 23.7 0.0 2.7 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Lyase_1 PF00206.15 CDO72379.1 - 9.7e-119 396.1 0.0 1.2e-118 395.8 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CDO72379.1 - 2.4e-20 72.3 0.0 5.6e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 CDO72379.1 - 0.02 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PEX11 PF05648.9 CDO72380.1 - 3.8e-49 166.9 1.5 4.3e-49 166.7 1.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4190 PF13828.1 CDO72380.1 - 0.013 14.9 1.0 5.5 6.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) Radical_SAM PF04055.16 CDO72381.1 - 4.5e-08 33.4 0.1 8.6e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Glyco_transf_8 PF01501.15 CDO72382.1 - 4.6e-14 52.3 0.1 5.9e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Peptidase_M22 PF00814.20 CDO72383.1 - 2.5e-82 276.4 0.0 2.9e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family HTH_13 PF11972.3 CDO72383.1 - 0.042 13.7 0.3 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain AlaDh_PNT_N PF05222.10 CDO72384.1 - 1.5e-11 44.4 0.0 2.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CDO72384.1 - 2.2e-05 24.0 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Acyltransferase PF01553.16 CDO72387.1 - 1.7e-20 72.7 0.0 2.7e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF1570 PF07607.6 CDO72387.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) Aa_trans PF01490.13 CDO72388.1 - 6.5e-32 110.5 37.8 8.1e-32 110.1 26.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Enoyl_reductase PF12241.3 CDO72388.1 - 0.071 12.0 0.9 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region DUF4239 PF14023.1 CDO72388.1 - 0.81 9.0 4.3 0.23 10.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) LRR_4 PF12799.2 CDO72389.1 - 8.3e-05 22.1 0.7 0.17 11.5 0.0 3.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CDO72389.1 - 0.00047 19.9 0.4 1.4 9.2 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_8 PF13855.1 CDO72389.1 - 0.00077 19.1 1.7 0.056 13.2 0.0 3.6 4 1 1 5 5 5 1 Leucine rich repeat LRR_7 PF13504.1 CDO72389.1 - 0.007 16.3 0.8 32 5.3 0.0 5.4 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 CDO72389.1 - 0.14 12.3 0.4 1.7e+02 2.8 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Abhydrolase_6 PF12697.2 CDO72390.1 - 3.3e-19 69.6 0.4 3.9e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO72390.1 - 4.9e-09 36.0 0.1 0.00023 20.9 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO72390.1 - 3e-06 26.9 0.0 4.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 CDO72390.1 - 0.027 12.9 0.0 0.046 12.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family Erythro_esteras PF05139.9 CDO72391.1 - 2e-103 346.2 0.9 3e-103 345.6 0.6 1.3 1 0 0 1 1 1 1 Erythromycin esterase Herpes_gE PF02480.11 CDO72391.1 - 0.021 13.1 0.3 0.039 12.2 0.2 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 CDO72391.1 - 0.037 13.7 0.4 0.037 13.7 0.3 3.4 1 1 2 3 3 3 0 TMEM154 protein family Tmemb_9 PF05434.6 CDO72391.1 - 0.17 11.6 0.0 0.72 9.5 0.0 1.9 2 0 0 2 2 2 0 TMEM9 DUF605 PF04652.11 CDO72391.1 - 2.1 7.6 15.0 4.6 6.5 10.4 1.5 1 0 0 1 1 1 0 Vta1 like DUF668 PF05003.7 CDO72393.1 - 0.037 14.2 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF668) DUF3543 PF12063.3 CDO72393.1 - 0.13 11.4 0.4 0.24 10.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Septin PF00735.13 CDO72394.1 - 1.3e-108 362.3 0.0 2.2e-108 361.5 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CDO72394.1 - 8e-06 25.8 0.0 1.7e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CDO72394.1 - 0.00035 20.4 4.4 0.026 14.3 0.0 2.9 2 1 1 3 3 3 2 Dynamin family AAA_17 PF13207.1 CDO72394.1 - 0.0018 19.0 1.3 0.013 16.3 0.0 2.5 1 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CDO72394.1 - 0.0059 15.8 0.3 0.031 13.4 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CDO72394.1 - 0.0084 15.2 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 CDO72394.1 - 0.0092 16.4 0.2 0.045 14.2 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CDO72394.1 - 0.022 14.2 1.0 0.036 13.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 CDO72394.1 - 0.029 13.7 0.0 0.37 10.2 0.0 2.4 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain IIGP PF05049.8 CDO72394.1 - 0.089 11.5 0.0 0.2 10.4 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) CPSF100_C PF13299.1 CDO72394.1 - 0.12 12.5 1.6 0.2 11.8 1.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MutS_V PF00488.16 CDO72395.1 - 1.5e-79 266.7 0.0 2.4e-79 266.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CDO72395.1 - 1.1e-42 146.1 0.0 3.4e-42 144.5 0.0 1.8 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CDO72395.1 - 8.9e-24 83.6 0.0 3.7e-23 81.7 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 CDO72395.1 - 4.9e-10 39.6 0.4 1.1e-09 38.5 0.0 1.8 2 0 0 2 2 2 1 MutS domain II AAA_23 PF13476.1 CDO72395.1 - 0.00061 20.1 0.3 0.0096 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CDO72395.1 - 0.0023 17.4 0.0 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MutS_IV PF05190.13 CDO72395.1 - 0.008 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 CDO72395.1 - 0.042 13.7 0.0 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF3126 PF11324.3 CDO72395.1 - 0.046 13.3 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) Aconitase PF00330.15 CDO72396.1 - 5.7e-146 486.6 0.5 3.8e-143 477.3 0.4 2.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CDO72396.1 - 8.8e-36 122.9 0.0 1.8e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 CDO72396.1 - 0.00022 19.9 0.0 0.00041 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF521) ATG16 PF08614.6 CDO72398.1 - 6.1e-40 137.1 18.2 3.9e-24 85.5 4.4 2.3 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) IncA PF04156.9 CDO72398.1 - 0.0011 18.5 20.8 0.035 13.6 1.7 2.5 2 1 0 2 2 2 2 IncA protein DUF2457 PF10446.4 CDO72398.1 - 0.0024 16.6 2.6 0.0024 16.6 1.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2457) TMF_TATA_bd PF12325.3 CDO72398.1 - 0.013 15.2 24.3 0.33 10.7 5.1 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 CDO72398.1 - 0.19 11.5 5.4 0.33 10.7 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Kinesin-related PF06548.6 CDO72398.1 - 0.22 10.0 13.0 0.099 11.1 6.9 1.7 2 0 0 2 2 2 0 Kinesin-related Snapin_Pallidin PF14712.1 CDO72398.1 - 0.27 11.5 14.5 0.72 10.2 3.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin RPA_interact_N PF14766.1 CDO72398.1 - 0.45 10.0 3.3 11 5.6 0.1 3.0 3 0 0 3 3 3 0 Replication protein A interacting N-terminal DUF3782 PF12644.2 CDO72398.1 - 0.56 10.0 6.3 4.8 7.0 4.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) DUF904 PF06005.7 CDO72398.1 - 1.1 9.6 27.1 0.27 11.5 5.3 4.7 3 2 1 4 4 4 0 Protein of unknown function (DUF904) DUF972 PF06156.8 CDO72398.1 - 1.2 9.5 17.1 0.23 11.8 2.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Flagellar_rod PF05149.7 CDO72398.1 - 1.3 8.1 14.6 5.9 5.9 9.6 2.2 1 1 0 1 1 1 0 Paraflagellar rod protein TPR_MLP1_2 PF07926.7 CDO72398.1 - 2.2 8.0 20.3 0.32 10.7 2.5 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein FlgN PF05130.7 CDO72398.1 - 2.9 8.1 22.1 23 5.2 12.3 2.9 1 1 2 3 3 3 0 FlgN protein FlxA PF14282.1 CDO72398.1 - 4.4 7.3 17.3 0.79 9.7 1.0 3.4 3 2 0 3 3 3 0 FlxA-like protein ING PF12998.2 CDO72398.1 - 9.2 6.5 12.6 1.5 9.1 2.0 2.9 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Ras PF00071.17 CDO72399.1 - 1.3e-57 193.7 0.2 1.5e-57 193.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO72399.1 - 1.1e-18 67.8 0.1 2.7e-18 66.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CDO72399.1 - 3.4e-14 52.4 0.0 4.3e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO72399.1 - 1.5e-07 30.7 0.1 1.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDO72399.1 - 4e-07 29.6 0.0 6.6e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDO72399.1 - 7.2e-07 29.1 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CDO72399.1 - 0.00066 19.8 0.0 0.0012 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 CDO72399.1 - 0.00069 19.2 0.4 0.04 13.4 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CDO72399.1 - 0.00089 18.7 0.1 0.17 11.3 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 CDO72399.1 - 0.0016 17.6 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 CDO72399.1 - 0.0028 16.7 0.2 0.05 12.6 0.0 2.2 2 1 0 2 2 2 1 Septin cobW PF02492.14 CDO72399.1 - 0.0051 16.2 0.0 0.02 14.3 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CDO72399.1 - 0.0066 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase SRPRB PF09439.5 CDO72399.1 - 0.0069 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 CDO72399.1 - 0.0075 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CDO72399.1 - 0.0092 15.7 0.1 0.017 14.8 0.0 1.5 2 0 0 2 2 2 1 NTPase MobB PF03205.9 CDO72399.1 - 0.013 15.2 0.1 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CDO72399.1 - 0.017 14.8 0.0 0.063 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDO72399.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 CDO72399.1 - 0.02 14.3 0.1 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 CDO72399.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 CDO72399.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Oxysterol_BP PF01237.13 CDO72400.1 - 1.3e-112 375.8 0.0 2.5e-112 374.8 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 CDO72400.1 - 4.7e-16 58.6 0.2 1.8e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 CDO72400.1 - 8.5e-06 25.9 0.0 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CDO72400.1 - 0.023 14.9 0.7 0.44 10.8 0.1 2.7 1 1 1 2 2 2 0 Pleckstrin homology domain Glyco_hydro_3_C PF01915.17 CDO72401.1 - 6.8e-59 199.1 4.3 3.7e-58 196.7 2.2 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 CDO72401.1 - 1.1e-52 178.8 2.0 8.4e-42 143.1 1.1 3.7 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 CDO72401.1 - 3.9e-18 65.1 0.0 1e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain RRM_1 PF00076.17 CDO72404.1 - 2.3e-40 136.0 0.0 1.9e-13 49.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO72404.1 - 1.7e-30 104.8 0.0 8.4e-10 38.4 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO72404.1 - 2.6e-19 68.8 0.0 8.5e-09 35.1 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO72404.1 - 0.027 14.2 0.0 0.91 9.3 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Band_7 PF01145.20 CDO72405.1 - 4.7e-24 85.2 1.4 8.8e-24 84.3 1.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.3 CDO72405.1 - 0.00038 19.4 2.7 0.00054 18.9 1.9 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial TrbC_Ftype PF09673.5 CDO72407.1 - 0.046 13.3 0.0 2.4 7.8 0.0 2.5 1 1 1 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Cnd1 PF12717.2 CDO72407.1 - 0.086 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 OS-D PF03392.8 CDO72407.1 - 0.31 11.0 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D Asn_synthase PF00733.16 CDO72408.1 - 2.3e-44 151.8 0.0 3.2e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 CDO72408.1 - 0.089 12.0 0.0 0.16 11.2 0.0 1.5 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC HA2 PF04408.18 CDO72409.1 - 2.7e-21 75.4 0.0 1.2e-20 73.4 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CDO72409.1 - 6e-20 71.1 0.0 1.4e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CDO72409.1 - 2.8e-12 46.3 0.1 5.3e-11 42.2 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO72409.1 - 5.5e-07 29.2 0.0 1.7e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CDO72409.1 - 1.1e-06 28.8 0.5 2.9e-05 24.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 CDO72409.1 - 0.0012 19.2 5.8 0.31 11.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain ResIII PF04851.10 CDO72409.1 - 0.0091 15.8 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit KaiC PF06745.8 CDO72409.1 - 0.012 14.7 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 CDO72409.1 - 0.056 12.8 0.1 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain 6PGD PF00393.14 CDO72411.1 - 8.2e-132 438.7 0.0 1e-131 438.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CDO72411.1 - 4.5e-49 166.4 0.0 6.4e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Aminotran_4 PF01063.14 CDO72412.1 - 1e-19 70.9 0.0 2.3e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Aminotransferase class IV GreA_GreB_N PF03449.10 CDO72412.1 - 0.2 11.7 0.0 0.47 10.5 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal IBR PF01485.16 CDO72415.1 - 1e-08 34.8 24.8 2.2e-05 24.2 8.1 2.8 2 0 0 2 2 2 2 IBR domain HIT PF01230.18 CDO72416.1 - 6.5e-18 65.0 0.7 5.3e-16 58.9 0.0 2.4 1 1 1 2 2 2 2 HIT domain DcpS_C PF11969.3 CDO72416.1 - 0.00015 21.9 0.2 0.0004 20.5 0.1 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Glucosamine_iso PF01182.15 CDO72417.1 - 2.2e-66 223.4 0.0 2.6e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Lac_bphage_repr PF06543.7 CDO72417.1 - 0.02 14.4 0.1 0.047 13.2 0.1 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor PXA PF02194.10 CDO72418.1 - 1.4e-10 41.0 0.0 1.7e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 PXA domain LGFP PF08310.6 CDO72419.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 LGFP repeat RRM_6 PF14259.1 CDO72420.1 - 3.2e-09 36.6 0.0 5.2e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 CDO72420.1 - 1.5e-08 34.6 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 CDO72420.1 - 1.1e-07 31.6 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO72420.1 - 0.0021 17.6 0.0 0.0067 16.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CDO72420.1 - 0.027 14.3 0.1 0.065 13.0 0.1 1.6 1 0 0 1 1 1 0 RNA binding motif TMEM247 PF15444.1 CDO72420.1 - 4.6 7.0 5.6 9.1 6.0 3.9 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 DUF4613 PF15390.1 CDO72420.1 - 7.6 4.5 7.9 12 3.8 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) IBR PF01485.16 CDO72421.1 - 3.5e-10 39.6 26.8 6e-06 26.0 2.2 2.8 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 CDO72421.1 - 8.5e-06 25.5 3.0 8.5e-06 25.5 2.1 3.8 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDO72421.1 - 0.0027 17.7 2.7 0.0027 17.7 1.9 3.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO72421.1 - 0.0049 16.5 0.6 0.0049 16.5 0.4 3.9 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) LppC PF04348.8 CDO72422.1 - 0.093 11.2 0.1 0.1 11.1 0.1 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein Sld5 PF05916.6 CDO72423.1 - 0.0072 16.6 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein LysM PF01476.15 CDO72424.1 - 2.2e-14 53.0 2.2 2.8e-07 30.3 0.2 2.3 2 0 0 2 2 2 2 LysM domain DEC-1_N PF04625.8 CDO72424.1 - 0.13 10.9 3.8 0.14 10.7 2.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region fn2 PF00040.14 CDO72424.1 - 0.28 11.2 2.8 0.48 10.4 0.0 2.5 3 0 0 3 3 3 0 Fibronectin type II domain ParA PF10609.4 CDO72425.1 - 4.3e-31 106.6 0.2 7.3e-31 105.8 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CDO72425.1 - 2.7e-15 56.3 0.0 5.1e-15 55.3 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CDO72425.1 - 3.3e-07 30.3 0.0 1.7e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CDO72425.1 - 0.00058 19.0 0.0 0.0012 17.9 0.0 1.5 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 CDO72425.1 - 0.0036 16.3 3.3 0.0046 16.0 0.4 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 CDO72425.1 - 0.0073 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CDO72425.1 - 0.055 12.6 0.1 0.087 11.9 0.1 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DEAD PF00270.24 CDO72426.1 - 2.5e-20 72.6 0.0 1.2e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CDO72426.1 - 7.2e-20 71.5 0.0 1.7e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CDO72426.1 - 2.2e-19 69.0 0.0 4.8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CDO72426.1 - 0.0015 18.6 0.0 0.011 15.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain G-patch PF01585.18 CDO72428.1 - 1.3e-11 44.0 0.1 3.8e-11 42.5 0.1 1.9 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 CDO72428.1 - 9e-06 25.6 5.0 1.5e-05 24.9 3.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CDO72428.1 - 3.7e-05 23.7 1.4 5.7e-05 23.1 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.2 CDO72428.1 - 0.00019 21.1 0.0 0.00019 21.1 0.0 2.4 3 0 0 3 3 3 1 DExH-box splicing factor binding site zf-C2H2_2 PF12756.2 CDO72428.1 - 0.0056 16.7 0.6 0.0092 16.0 0.4 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF4460 PF14687.1 CDO72428.1 - 0.033 13.9 0.1 3.1 7.5 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4460) Kri1 PF05178.7 CDO72428.1 - 0.054 13.7 1.0 0.054 13.7 0.7 2.1 2 0 0 2 2 2 0 KRI1-like family zf-DBF PF07535.7 CDO72428.1 - 0.056 13.1 2.7 0.099 12.3 1.9 1.3 1 0 0 1 1 1 0 DBF zinc finger Topoisom_I_N PF02919.10 CDO72428.1 - 0.079 12.2 2.6 0.12 11.6 1.8 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF2624 PF11116.3 CDO72428.1 - 0.12 12.8 0.5 0.24 11.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) MOZART2 PF12926.2 CDO72428.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Evr1_Alr PF04777.8 CDO72428.1 - 0.37 10.7 2.6 0.64 9.9 1.8 1.3 1 0 0 1 1 1 0 Erv1 / Alr family Thioredoxin_2 PF13098.1 CDO72428.1 - 0.88 9.7 2.9 1.2 9.4 1.6 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain FTCD_C PF04961.7 CDO72428.1 - 8.6 5.7 9.2 2 7.7 1.1 2.2 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase Bromodomain PF00439.20 CDO72429.1 - 2.9e-42 142.4 0.1 7.1e-24 83.5 0.1 2.7 2 0 0 2 2 2 2 Bromodomain SPT6_acidic PF14632.1 CDO72429.1 - 0.011 15.9 11.2 0.042 14.0 7.7 2.1 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF1664 PF07889.7 CDO72429.1 - 0.76 9.5 3.8 0.4 10.4 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.27 CDO72430.1 - 1.9e-23 81.4 14.0 2.3e-07 30.4 0.2 6.9 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 CDO72430.1 - 2.6e-06 27.3 0.1 0.48 10.0 0.0 3.4 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A LRV PF01816.12 CDO72430.1 - 0.25 11.6 1.6 0.47 10.7 0.1 2.3 2 0 0 2 2 2 0 Leucine rich repeat variant Rhodanese PF00581.15 CDO72433.1 - 8.2e-19 68.0 0.0 1.4e-18 67.2 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Multi_ubiq PF14452.1 CDO72433.1 - 0.054 13.4 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Multiubiquitin Ctr PF04145.10 CDO72434.1 - 8.5e-28 97.2 0.0 1.1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family ATP_synt_I PF03899.10 CDO72434.1 - 1.8 8.8 9.2 0.61 10.2 0.1 2.2 2 0 0 2 2 2 0 ATP synthase I chain DUF515 PF04415.7 CDO72435.1 - 1.5 6.9 4.1 1.8 6.7 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF1180 PF06679.7 CDO72435.1 - 1.5 8.6 5.1 2.3 8.0 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) eIF3_N PF09440.5 CDO72436.1 - 0.048 13.8 0.4 0.059 13.5 0.3 1.1 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Alpha-amylase_N PF02903.9 CDO72436.1 - 0.083 12.8 0.2 0.086 12.8 0.2 1.1 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain V-ATPase_C PF03223.10 CDO72437.1 - 5.1e-97 325.0 2.1 6.4e-52 176.7 0.1 2.0 1 1 1 2 2 2 2 V-ATPase subunit C Urb2 PF10441.4 CDO72438.1 - 6.8e-32 110.8 0.0 3e-31 108.7 0.0 2.0 2 0 0 2 2 2 1 Urb2/Npa2 family Beta_elim_lyase PF01212.16 CDO72439.1 - 3.9e-59 200.1 0.0 4.7e-39 134.2 0.0 2.5 2 1 1 3 3 3 2 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CDO72439.1 - 0.043 12.8 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CDO72439.1 - 0.07 11.4 0.0 0.1 10.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme zf-met2 PF12907.2 CDO72440.1 - 4e-17 61.9 2.0 5.3e-17 61.5 1.4 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 CDO72440.1 - 4e-10 40.2 10.6 4e-10 40.2 7.3 1.9 2 0 0 2 2 2 1 4F5 protein family HypA PF01155.14 CDO72440.1 - 0.028 14.1 0.2 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-Tim10_DDP PF02953.10 CDO72441.1 - 1.4e-23 81.9 0.4 1.6e-23 81.7 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger WD40 PF00400.27 CDO72442.1 - 5.8e-11 41.8 17.9 0.003 17.3 0.0 6.6 8 0 0 8 8 8 4 WD domain, G-beta repeat Bd3614_N PF14442.1 CDO72442.1 - 3.3 7.6 7.3 16 5.4 0.5 2.9 3 0 0 3 3 3 0 Bd3614-like deaminase N-terminal Mpv17_PMP22 PF04117.7 CDO72443.1 - 2.4e-24 84.7 0.5 4.6e-24 83.8 0.2 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family PTH2 PF01981.11 CDO72444.1 - 9.2e-07 28.5 0.1 1.8e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 DEAD PF00270.24 CDO72445.1 - 7.7e-43 145.9 0.0 1.4e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO72445.1 - 4.9e-22 77.5 0.0 9.9e-22 76.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CDO72445.1 - 3.2e-19 68.2 0.3 6.7e-19 67.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CDO72445.1 - 0.067 13.0 0.0 0.25 11.1 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NOA36 PF06524.7 CDO72445.1 - 6.7 5.8 6.9 5.9 6.0 3.6 1.6 2 0 0 2 2 2 0 NOA36 protein UPF0121 PF03661.8 CDO72446.1 - 5.7e-20 71.5 0.0 7.5e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) NdhL PF10716.4 CDO72446.1 - 0.084 12.6 7.0 0.095 12.4 0.3 2.5 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit Tim17 PF02466.14 CDO72447.1 - 0.034 14.1 1.4 0.043 13.8 1.0 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family DUF1700 PF08006.6 CDO72447.1 - 5.2 6.3 6.5 6.1 6.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) CBS PF00571.23 CDO72448.1 - 2.2e-36 123.3 6.2 8e-10 38.3 0.0 4.4 4 0 0 4 4 4 4 CBS domain Sgf11 PF08209.6 CDO72448.1 - 3.7e-14 51.7 0.7 8.4e-14 50.5 0.5 1.6 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) MFS_1 PF07690.11 CDO72449.1 - 6e-08 31.7 11.1 6e-08 31.7 7.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.1 CDO72450.1 - 0.29 11.1 0.1 0.29 11.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Bac_rhamnosid PF05592.6 CDO72451.1 - 3.9e-31 107.8 0.1 1.8e-25 89.1 0.2 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 CDO72451.1 - 0.018 13.7 0.4 0.033 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF608 CarboxypepD_reg PF13620.1 CDO72451.1 - 0.065 13.2 0.3 12 6.0 0.0 2.7 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain SNARE PF05739.14 CDO72452.1 - 1.8e-07 30.6 0.4 2.3e-07 30.4 0.3 1.1 1 0 0 1 1 1 1 SNARE domain DUF4234 PF14018.1 CDO72452.1 - 0.0042 16.7 1.5 0.0062 16.2 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4234) Synaptobrevin PF00957.16 CDO72452.1 - 0.087 12.4 0.7 0.18 11.4 0.5 1.4 1 0 0 1 1 1 0 Synaptobrevin Peptidase_C48 PF02902.14 CDO72453.1 - 5.6e-38 130.7 0.1 5.6e-38 130.7 0.1 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Pkinase PF00069.20 CDO72454.1 - 1.9e-49 168.1 0.0 2.5e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO72454.1 - 2.1e-26 92.5 0.0 2.7e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO72454.1 - 0.0016 18.2 0.0 0.0039 16.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CDO72454.1 - 0.007 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Neuromodulin PF06614.6 CDO72454.1 - 0.041 13.8 3.0 0.061 13.2 2.1 1.2 1 0 0 1 1 1 0 Neuromodulin YrbL-PhoP_reg PF10707.4 CDO72454.1 - 0.045 13.0 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 CDO72454.1 - 0.071 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Yippee-Mis18 PF03226.9 CDO72455.1 - 3.6e-17 62.1 0.0 3.6e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 CDO72455.1 - 0.03 14.3 0.0 0.032 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.3 CDO72455.1 - 0.038 13.8 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of RIG-I adh_short PF00106.20 CDO72456.1 - 0.012 15.5 0.1 0.16 11.8 0.0 2.4 2 1 0 2 2 2 0 short chain dehydrogenase Cornichon PF03311.9 CDO72459.1 - 5.7e-53 178.4 5.3 6.4e-53 178.2 3.7 1.0 1 0 0 1 1 1 1 Cornichon protein ATP11 PF06644.6 CDO72460.1 - 7.5 5.9 7.1 8.1 5.8 4.9 1.1 1 0 0 1 1 1 0 ATP11 protein FbpA PF05833.6 CDO72460.1 - 9.4 4.6 12.8 11 4.3 8.8 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Cerato-platanin PF07249.7 CDO72461.1 - 9.2e-39 132.1 4.6 1.7e-38 131.2 3.2 1.4 1 0 0 1 1 1 1 Cerato-platanin PRMT5 PF05185.11 CDO72463.1 - 1.4e-149 498.8 0.0 9.3e-128 426.9 0.0 2.1 1 1 1 2 2 2 2 PRMT5 arginine-N-methyltransferase Ank_5 PF13857.1 CDO72463.1 - 2.1e-12 46.8 0.1 2.7e-10 40.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CDO72463.1 - 2.3e-12 47.0 0.0 3.3e-11 43.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDO72463.1 - 4.9e-12 46.0 0.0 3e-06 27.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CDO72463.1 - 7.5e-11 41.2 3.3 2.1e-07 30.3 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CDO72463.1 - 3e-09 36.2 0.0 4.1e-05 23.4 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Methyltransf_18 PF12847.2 CDO72463.1 - 0.00023 21.6 0.0 0.00054 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CDO72463.1 - 0.0052 16.3 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 CDO72463.1 - 0.0061 16.5 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO72463.1 - 0.02 15.3 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GATA PF00320.22 CDO72464.1 - 3.8e-14 51.7 3.0 9.1e-14 50.5 2.1 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 CDO72464.1 - 0.0017 18.3 0.1 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold LRR_4 PF12799.2 CDO72465.1 - 5.8e-33 111.9 37.2 1.7e-11 43.4 2.2 4.9 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO72465.1 - 6.1e-25 86.7 19.7 4.2e-10 39.2 3.6 4.3 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 CDO72465.1 - 4.6e-14 50.2 20.6 0.08 13.0 0.2 8.2 8 0 0 8 8 8 6 Leucine Rich Repeat LRR_9 PF14580.1 CDO72465.1 - 4.1e-12 46.0 5.9 1.2e-08 34.6 0.5 2.5 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.1 CDO72465.1 - 7.3e-12 44.0 21.6 0.087 12.9 0.1 8.2 4 2 5 9 9 9 5 Leucine Rich repeat LRR_7 PF13504.1 CDO72465.1 - 4.1e-08 32.1 16.6 1.3 9.5 0.1 7.8 8 0 0 8 8 8 2 Leucine rich repeat LRR_5 PF13306.1 CDO72465.1 - 0.035 13.8 0.4 0.1 12.2 0.1 1.8 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) DUF3306 PF11748.3 CDO72465.1 - 0.12 12.9 3.3 0.3 11.7 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) DUF4078 PF13300.1 CDO72466.1 - 5.8e-20 71.2 6.3 5.8e-20 71.2 4.3 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4078) UCR_14kD PF02271.11 CDO72466.1 - 0.025 14.3 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Lactamase_B PF00753.22 CDO72467.1 - 5.8e-10 39.1 4.1 4.3e-09 36.2 2.9 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CDO72467.1 - 3.6e-06 26.6 0.1 6.3e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain LPAM_2 PF13627.1 CDO72467.1 - 0.47 10.2 5.9 5.5 6.8 0.3 2.4 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site ThiS PF02597.15 CDO72468.1 - 6.9e-07 29.6 0.0 6.3e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 ThiS family TPK_B1_binding PF04265.9 CDO72469.1 - 9.8e-20 70.0 0.1 1.5e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 CDO72469.1 - 1.5e-15 56.8 0.3 2.1e-14 53.1 0.2 2.1 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain CS PF04969.11 CDO72470.1 - 3.1e-09 37.2 0.0 7.4e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 CS domain Erg28 PF03694.8 CDO72472.1 - 2.4e-34 117.6 1.0 3.2e-34 117.2 0.7 1.2 1 0 0 1 1 1 1 Erg28 like protein LRR_6 PF13516.1 CDO72473.1 - 1.1e-06 28.0 0.3 0.00085 19.1 0.0 4.1 5 0 0 5 5 5 1 Leucine Rich repeat F-box-like PF12937.2 CDO72473.1 - 0.00027 20.6 0.1 0.00027 20.6 0.0 2.1 2 1 0 2 2 2 1 F-box-like LRR_7 PF13504.1 CDO72473.1 - 0.0056 16.6 2.4 6.4 7.4 0.0 5.3 5 0 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 CDO72473.1 - 0.0056 16.5 0.6 2 8.7 0.1 4.5 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_4 PF12799.2 CDO72473.1 - 0.011 15.3 0.4 1.1 8.9 0.0 3.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO72473.1 - 0.012 15.3 0.0 1.1 9.0 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat Na_Ca_ex PF01699.19 CDO72474.1 - 1.3e-32 112.3 27.8 4.2e-19 68.5 7.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein adh_short PF00106.20 CDO72475.1 - 4.6e-60 202.3 16.9 3.7e-32 111.5 3.4 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CDO72475.1 - 1.5e-24 86.6 11.5 1.1e-15 57.7 1.7 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 CDO72475.1 - 1.8e-16 59.6 0.0 4.3e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CDO72475.1 - 2.3e-13 50.0 0.0 6.8e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.13 CDO72475.1 - 2.4e-05 24.0 10.6 0.0035 16.9 1.3 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 CDO72475.1 - 0.0011 18.2 4.6 0.26 10.4 0.1 3.5 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 CDO72475.1 - 0.047 13.4 4.3 0.46 10.2 0.1 3.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 CDO72475.1 - 0.081 11.9 8.7 0.16 11.0 0.5 2.9 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FRD2 PF03197.8 CDO72475.1 - 0.098 13.2 0.1 21 5.7 0.0 2.8 2 0 0 2 2 2 0 Bacteriophage FRD2 protein DUF543 PF04418.7 CDO72475.1 - 0.65 9.9 5.5 9.5 6.2 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Shikimate_DH PF01488.15 CDO72475.1 - 3.2 7.8 7.1 4.8 7.2 0.3 3.1 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase CoA_transf_3 PF02515.12 CDO72476.1 - 1.5e-26 92.8 0.0 2.2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Drf_GBD PF06371.8 CDO72477.1 - 6.3e-13 48.5 0.0 4.2e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain CRAL_TRIO PF00650.15 CDO72479.1 - 2.8e-31 108.1 0.0 3.7e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CDO72479.1 - 0.0019 18.2 0.3 0.0057 16.7 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CDO72479.1 - 0.0045 16.8 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Complex1_LYR PF05347.10 CDO72480.1 - 1.4e-13 50.3 0.6 2.2e-13 49.7 0.1 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CDO72480.1 - 4.1e-12 46.1 0.5 5.7e-12 45.6 0.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CDO72480.1 - 0.022 15.2 0.5 0.028 14.8 0.3 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Glyco_hydro_17 PF00332.13 CDO72482.1 - 6.4e-08 31.9 6.1 2.5e-07 30.0 1.4 2.5 1 1 0 2 2 2 2 Glycosyl hydrolases family 17 RhoGAP PF00620.22 CDO72483.1 - 6e-38 129.8 0.0 1.1e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 CDO72483.1 - 0.0012 17.8 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF1899 PF08953.6 CDO72483.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) MRI PF15325.1 CDO72484.1 - 0.14 13.1 0.2 0.26 12.2 0.2 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection IncA PF04156.9 CDO72485.1 - 0.00077 19.1 0.7 0.00077 19.1 0.5 2.4 2 1 0 2 2 2 1 IncA protein Exo70 PF03081.10 CDO72485.1 - 0.0025 16.6 0.0 0.0045 15.8 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Mnd1 PF03962.10 CDO72485.1 - 0.003 17.2 6.7 0.003 17.2 4.7 2.1 2 0 0 2 2 2 1 Mnd1 family CENP-Q PF13094.1 CDO72485.1 - 0.0067 16.4 4.3 0.0067 16.4 3.0 2.3 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF2607 PF10795.4 CDO72485.1 - 0.079 12.7 0.0 5.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2607) DUF1423 PF07227.6 CDO72485.1 - 0.11 11.1 6.7 0.21 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) Dor1 PF04124.7 CDO72485.1 - 0.12 10.7 6.9 0.37 9.1 0.0 2.1 2 0 0 2 2 2 0 Dor1-like family DUF1796 PF08795.5 CDO72485.1 - 0.14 11.7 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) Ax_dynein_light PF10211.4 CDO72485.1 - 0.31 10.8 14.4 0.038 13.8 6.4 1.9 2 0 0 2 2 2 0 Axonemal dynein light chain Med9 PF07544.8 CDO72485.1 - 1.1 9.0 11.1 0.35 10.6 5.7 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Phlebovirus_NSM PF07246.6 CDO72485.1 - 1.2 8.1 8.2 2.5 7.1 5.7 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Atg14 PF10186.4 CDO72485.1 - 3.6 6.4 12.2 0.56 9.1 4.9 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 LCD1 PF09798.4 CDO72485.1 - 4.4 5.1 11.8 0.56 8.1 4.9 1.7 2 0 0 2 2 2 0 DNA damage checkpoint protein DUF4446 PF14584.1 CDO72485.1 - 7.1 6.4 7.5 6.4 6.5 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Ferritin_2 PF13668.1 CDO72486.1 - 1.1e-11 44.8 0.2 1.6e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Oxidored_FMN PF00724.15 CDO72487.1 - 1.1e-102 343.5 0.0 1.3e-102 343.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pectate_lyase_3 PF12708.2 CDO72488.1 - 1e-76 257.9 20.8 7.9e-64 215.8 7.7 3.1 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 CDO72488.1 - 4.3e-05 22.8 4.1 0.0083 15.5 0.4 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Ribosomal_L5_C PF00673.16 CDO72489.1 - 2.5e-21 75.2 0.0 4.4e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CDO72489.1 - 1.1e-12 47.4 0.0 3e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L5 Josephin PF02099.12 CDO72490.1 - 4.4e-09 36.1 0.0 8.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Josephin UIM PF02809.15 CDO72490.1 - 0.012 15.1 3.5 0.012 15.1 2.4 5.0 5 0 0 5 5 5 0 Ubiquitin interaction motif ATG27 PF09451.5 CDO72491.1 - 2.2e-54 184.4 0.0 2.7e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 CDO72491.1 - 0.0021 17.1 0.0 0.0035 16.3 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor AIM24 PF01987.12 CDO72493.1 - 8.6e-53 178.9 0.2 1e-52 178.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 FixQ PF05545.6 CDO72494.1 - 0.0069 16.0 0.3 0.014 15.0 0.2 1.5 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ PIH1 PF08190.7 CDO72494.1 - 0.085 12.2 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Syndecan PF01034.15 CDO72494.1 - 0.16 11.6 0.1 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain ILVD_EDD PF00920.16 CDO72495.1 - 3e-195 649.6 0.0 3.7e-195 649.2 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family TPR_11 PF13414.1 CDO72496.1 - 2.5e-23 81.5 1.5 7.2e-13 47.9 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CDO72496.1 - 3.6e-19 67.4 0.0 1.8e-05 24.1 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CDO72496.1 - 3.9e-17 60.7 2.0 0.00012 21.6 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDO72496.1 - 1.4e-14 54.2 6.4 4.2e-09 36.8 0.0 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO72496.1 - 2.8e-10 39.8 6.8 0.0082 16.6 0.0 5.7 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDO72496.1 - 8.2e-10 38.4 5.6 0.00012 21.9 0.0 3.7 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDO72496.1 - 2.1e-09 36.8 0.1 0.0025 17.8 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CDO72496.1 - 3.9e-09 35.6 0.0 0.42 10.5 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CDO72496.1 - 9.1e-08 31.3 0.4 0.14 12.0 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO72496.1 - 2.3e-07 31.0 1.6 0.089 13.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 CDO72496.1 - 9e-06 25.4 2.4 0.89 9.5 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 CDO72496.1 - 3.2e-05 23.1 1.3 0.024 13.7 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 CDO72496.1 - 0.00032 20.9 0.1 7.3 7.2 0.0 4.7 3 1 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CDO72496.1 - 0.0026 17.8 0.0 0.0068 16.5 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.9 CDO72496.1 - 0.0084 15.3 0.0 0.075 12.2 0.0 2.4 2 1 1 3 3 3 1 Coatomer epsilon subunit TPR_9 PF13371.1 CDO72496.1 - 0.058 13.2 2.0 2.2 8.2 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Calpain_inhib PF00748.14 CDO72496.1 - 0.084 13.2 1.2 0.2 12.0 0.8 1.7 1 1 0 1 1 1 0 Calpain inhibitor Dimer_Tnp_hAT PF05699.9 CDO72497.1 - 0.0021 17.6 0.0 0.0048 16.5 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Exo70 PF03081.10 CDO72498.1 - 0.0096 14.7 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit DUF1796 PF08795.5 CDO72498.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) DUF1204 PF06721.6 CDO72498.1 - 0.6 9.3 7.5 0.78 8.9 4.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1204) DUF3106 PF11304.3 CDO72498.1 - 0.95 9.9 6.4 0.18 12.2 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Kinetocho_Slk19 PF12709.2 CDO72498.1 - 2.2 8.4 7.9 0.27 11.3 2.0 2.1 2 0 0 2 2 2 0 Central kinetochore-associated Abhydrolase_4 PF08386.5 CDO72499.1 - 5.5e-12 45.4 0.0 1.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 CDO72499.1 - 1.5e-07 31.2 1.3 5.2e-07 29.4 1.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDO72499.1 - 0.0063 16.4 1.0 0.014 15.3 0.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family O-FucT PF10250.4 CDO72500.1 - 2.1e-12 46.8 0.3 7.1e-06 25.3 0.0 3.3 3 1 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase Abhydrolase_4 PF08386.5 CDO72501.1 - 8.7e-43 144.4 0.1 1.8e-20 72.7 0.0 2.5 2 0 0 2 2 2 2 TAP-like protein Abhydrolase_1 PF00561.15 CDO72501.1 - 6.5e-29 101.1 0.0 3.1e-12 46.5 0.0 4.7 4 2 0 4 4 4 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDO72501.1 - 5.4e-17 62.4 8.0 1.8e-07 31.2 1.0 4.3 2 2 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO72501.1 - 7e-07 29.0 0.0 0.044 13.5 0.0 3.6 2 2 0 2 2 2 2 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CDO72501.1 - 0.028 14.0 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase DUF1335 PF07056.6 CDO72501.1 - 0.24 11.1 0.0 2.6 7.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1335) DUF1100 PF06500.6 CDO72501.1 - 0.41 9.1 0.0 1.2 7.6 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) PC-Esterase PF13839.1 CDO72502.1 - 1.5e-07 31.5 0.0 1.2e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Esterase_phd PF10503.4 CDO72503.1 - 1.8e-23 82.9 0.3 3.1e-23 82.1 0.2 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 CDO72503.1 - 1.7e-10 40.3 13.4 4.7e-09 35.7 9.3 2.9 1 1 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 CDO72503.1 - 2.2e-10 40.1 0.4 4e-10 39.2 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDO72503.1 - 2.1e-07 30.8 0.2 2.8e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO72503.1 - 0.00061 19.7 0.6 0.00061 19.7 0.4 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 CDO72503.1 - 0.00069 18.4 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.15 CDO72503.1 - 0.0031 17.1 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 CDO72503.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 CDO72504.1 - 2.5e-20 72.7 0.0 3.9e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 CDO72504.1 - 1.1e-12 47.3 3.5 1.1e-12 47.3 2.4 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 CDO72504.1 - 3.4e-07 29.7 0.4 6.1e-07 28.8 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDO72504.1 - 2.5e-05 24.0 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO72504.1 - 5.5e-05 22.8 0.0 7.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDO72504.1 - 0.00071 19.5 0.1 0.0012 18.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CDO72504.1 - 0.0046 15.7 0.1 0.0046 15.7 0.1 2.1 3 0 0 3 3 3 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CDO72504.1 - 0.062 12.8 0.1 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AIRS_C PF02769.17 CDO72506.1 - 4.5e-46 156.6 0.2 2.2e-27 95.9 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CDO72506.1 - 5.2e-24 84.3 0.0 2.3e-23 82.2 0.0 2.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain GATase_5 PF13507.1 CDO72506.1 - 6.6e-14 51.4 0.0 1.1e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Glyco_tranf_2_3 PF13641.1 CDO72507.1 - 2.2e-24 86.5 0.0 3.8e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CDO72507.1 - 4.7e-09 36.1 0.0 7.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CDO72507.1 - 1.8e-08 33.8 0.0 5.6e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 CDO72507.1 - 1.1e-05 25.2 5.8 2e-05 24.3 4.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Pex14_N PF04695.8 CDO72507.1 - 1.6 8.7 5.9 1.6 8.7 2.8 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sugar_tr PF00083.19 CDO72508.1 - 1.4e-27 96.4 28.1 7.3e-15 54.4 3.9 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CDO72508.1 - 4.8e-20 71.5 21.5 1.1e-10 40.7 1.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2069 PF09842.4 CDO72508.1 - 0.02 14.8 0.9 0.02 14.8 0.7 1.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2069) MFS_2 PF13347.1 CDO72508.1 - 0.12 10.7 16.0 0.13 10.6 1.0 3.1 1 1 1 2 2 2 0 MFS/sugar transport protein Carn_acyltransf PF00755.15 CDO72509.1 - 1.3e-163 545.2 0.0 3.2e-162 540.6 0.0 2.0 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Taeniidae_ag PF05596.6 CDO72509.1 - 0.078 12.7 0.1 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Taeniidae antigen PRCC PF10253.4 CDO72510.1 - 0.19 12.4 1.8 0.24 12.0 1.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF605 PF04652.11 CDO72510.1 - 0.63 9.3 13.3 0.75 9.1 9.3 1.1 1 0 0 1 1 1 0 Vta1 like SKG6 PF08693.5 CDO72511.1 - 0.054 12.8 0.4 0.054 12.8 0.3 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Abhydrolase_1 PF00561.15 CDO72512.1 - 1.2e-14 54.4 0.0 2.5e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDO72512.1 - 7.7e-09 35.7 0.1 2.5e-08 34.1 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO72512.1 - 0.041 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family ETF_alpha PF00766.14 CDO72513.1 - 6.5e-36 121.8 1.7 6.7e-36 121.7 0.3 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 CDO72513.1 - 8.7e-35 119.8 0.5 1.7e-34 118.9 0.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain FAD_binding_3 PF01494.14 CDO72514.1 - 6.6e-13 48.4 0.0 4.8e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CDO72514.1 - 0.00023 21.1 0.1 0.00065 19.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO72514.1 - 0.0072 15.2 0.4 0.014 14.3 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CDO72514.1 - 0.048 12.3 0.4 0.9 8.0 0.0 2.1 1 1 0 2 2 2 0 Tryptophan halogenase NUC173 PF08161.7 CDO72515.1 - 1.7e-37 128.6 3.5 4.1e-35 120.9 0.2 3.6 4 0 0 4 4 4 2 NUC173 domain HEAT PF02985.17 CDO72515.1 - 1.2e-05 24.9 0.3 0.12 12.5 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 CDO72515.1 - 7.9e-05 23.0 1.2 0.55 10.7 0.0 5.1 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 CDO72515.1 - 0.00064 19.9 6.6 0.25 11.6 0.0 4.9 5 2 0 5 5 5 2 HEAT repeats Cnd1 PF12717.2 CDO72515.1 - 0.0016 18.2 0.7 0.96 9.2 0.0 3.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 RuvA_C PF07499.8 CDO72515.1 - 0.021 14.9 1.1 0.51 10.5 0.3 2.9 2 0 0 2 2 2 0 RuvA, C-terminal domain MOR2-PAG1_C PF14225.1 CDO72515.1 - 0.031 14.0 1.4 0.071 12.8 0.1 2.3 2 0 0 2 2 2 0 Cell morphogenesis C-terminal MMS19_C PF12460.3 CDO72515.1 - 0.96 8.1 16.5 0.48 9.0 0.2 4.5 5 2 0 5 5 5 0 RNAPII transcription regulator C-terminal Acyltransferase PF01553.16 CDO72516.1 - 5e-08 32.4 0.0 1.4e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Lip_A_acyltrans PF03279.8 CDO72516.1 - 0.098 11.5 2.0 0.29 9.9 0.0 2.4 2 1 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase Claudin_2 PF13903.1 CDO72517.1 - 0.0024 17.5 0.6 0.0032 17.1 0.4 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF998 PF06197.8 CDO72517.1 - 0.014 14.7 9.2 0.019 14.3 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Amastin PF07344.6 CDO72517.1 - 0.039 13.5 3.0 0.074 12.6 2.1 1.5 1 1 0 1 1 1 0 Amastin surface glycoprotein ABC2_membrane_2 PF12679.2 CDO72517.1 - 0.041 12.7 1.3 0.056 12.3 0.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SUR7 PF06687.7 CDO72517.1 - 1.3 8.5 5.5 0.81 9.2 1.1 2.0 1 1 0 2 2 2 0 SUR7/PalI family MRI PF15325.1 CDO72518.1 - 0.21 12.5 2.9 0.35 11.8 2.0 1.5 1 1 0 1 1 1 0 Modulator of retrovirus infection Bot1p PF12298.3 CDO72519.1 - 0.29 11.0 4.4 0.11 12.4 1.4 1.4 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein ICMT PF04140.9 CDO72520.1 - 1.1e-13 51.1 0.7 1.7e-12 47.3 0.1 2.7 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO72520.1 - 8.4e-12 45.1 3.5 1.2e-11 44.5 0.2 2.5 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO72520.1 - 2e-06 26.5 0.6 2.8e-06 26.1 0.4 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Abhydrolase_6 PF12697.2 CDO72521.1 - 3e-08 33.8 2.0 6.4e-08 32.7 1.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO72521.1 - 0.0023 17.6 0.0 0.015 15.0 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO72522.1 - 2.1e-13 50.7 0.7 2.8e-13 50.2 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO72522.1 - 2.2e-08 33.9 0.0 4.3e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO72522.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Aldo_ket_red PF00248.16 CDO72523.1 - 5.1e-71 238.7 0.0 5.8e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF659 PF04937.10 CDO72524.1 - 1.6e-07 30.9 0.1 3.7e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ADH_zinc_N PF00107.21 CDO72525.1 - 4.8e-21 74.6 0.2 6.6e-21 74.2 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO72525.1 - 2.6e-08 34.8 0.4 5.6e-08 33.7 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 CDO72525.1 - 0.0093 16.5 0.1 0.02 15.4 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain NAD_binding_3 PF03447.11 CDO72525.1 - 0.025 14.9 0.1 0.061 13.7 0.1 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain zf-H2C2_2 PF13465.1 CDO72526.1 - 2.4e-09 37.0 5.0 5.3e-08 32.7 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 CDO72526.1 - 0.00033 20.7 1.6 0.00033 20.7 1.1 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO72526.1 - 0.027 14.7 1.2 0.027 14.7 0.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger PAT1 PF09770.4 CDO72526.1 - 0.24 9.5 11.6 0.29 9.3 8.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ABC_tran PF00005.22 CDO72527.1 - 2.6e-49 167.0 0.0 1.3e-29 103.2 0.0 4.2 3 2 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 CDO72527.1 - 6e-16 59.2 0.2 0.0038 17.2 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 CDO72527.1 - 1.3e-13 50.6 0.0 4.5e-05 22.7 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 CDO72527.1 - 3e-08 33.2 0.1 6.1e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 CDO72527.1 - 4.9e-07 30.5 0.0 0.017 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CDO72527.1 - 6e-07 28.8 1.4 0.048 13.1 0.1 3.5 4 0 0 4 4 2 2 P-loop containing region of AAA domain Miro PF08477.8 CDO72527.1 - 1e-06 29.2 0.0 0.011 16.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 CDO72527.1 - 2.9e-06 27.4 0.0 0.022 14.8 0.0 3.8 4 0 0 4 4 3 1 AAA domain MMR_HSR1 PF01926.18 CDO72527.1 - 6.3e-06 26.1 0.0 0.062 13.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 CDO72527.1 - 6.5e-06 26.1 0.0 0.23 11.2 0.1 3.0 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_28 PF13521.1 CDO72527.1 - 2.4e-05 24.3 0.0 0.41 10.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 CDO72527.1 - 3.6e-05 23.6 0.0 0.029 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CDO72527.1 - 4.3e-05 22.7 0.0 0.034 13.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CDO72527.1 - 4.7e-05 22.9 0.9 0.47 9.8 0.0 3.4 4 0 0 4 4 3 2 AAA-like domain NACHT PF05729.7 CDO72527.1 - 7.6e-05 22.4 0.1 0.083 12.5 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_18 PF13238.1 CDO72527.1 - 0.00013 22.2 0.0 0.41 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CDO72527.1 - 0.00013 21.4 0.1 5 6.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 CDO72527.1 - 0.00014 21.8 4.8 1.5 8.7 0.3 4.2 4 1 0 4 4 3 2 AAA ATPase domain HEAT PF02985.17 CDO72527.1 - 0.00015 21.5 5.2 5.5 7.3 0.1 6.1 6 0 0 6 6 5 0 HEAT repeat ArgK PF03308.11 CDO72527.1 - 0.0002 20.2 0.2 0.069 11.9 0.0 2.3 2 0 0 2 2 2 1 ArgK protein MobB PF03205.9 CDO72527.1 - 0.00028 20.6 0.0 0.4 10.3 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CDO72527.1 - 0.00074 19.8 6.5 0.015 15.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain HEAT_2 PF13646.1 CDO72527.1 - 0.0015 18.7 11.1 0.077 13.2 0.1 4.7 2 1 3 5 5 4 1 HEAT repeats AAA_14 PF13173.1 CDO72527.1 - 0.0017 18.2 0.3 4.7 7.1 0.0 3.4 2 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 CDO72527.1 - 0.0022 17.8 0.0 1.7 8.5 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 CDO72527.1 - 0.0035 15.8 0.0 1.2 7.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CDO72527.1 - 0.0057 16.8 0.1 2.7 8.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 CDO72527.1 - 0.01 15.4 0.0 11 5.4 0.1 3.4 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 CDO72527.1 - 0.032 13.7 0.2 9.2 5.7 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 CDO72527.1 - 0.032 13.9 0.1 16 5.0 0.0 3.4 3 0 0 3 3 3 0 Archaeal ATPase Arf PF00025.16 CDO72527.1 - 0.039 13.2 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family HEAT_EZ PF13513.1 CDO72527.1 - 0.042 14.3 7.1 1.3 9.5 0.4 4.5 3 1 1 4 4 3 0 HEAT-like repeat Dynamin_N PF00350.18 CDO72527.1 - 0.044 13.6 0.0 0.75 9.5 0.0 2.7 3 0 0 3 3 2 0 Dynamin family cobW PF02492.14 CDO72527.1 - 0.05 13.0 0.2 13 5.1 0.2 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Tudor-knot PF11717.3 CDO72527.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain PduV-EutP PF10662.4 CDO72527.1 - 0.061 12.8 0.0 5.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 CDO72527.1 - 0.062 12.7 0.1 4.6 6.6 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF3584 PF12128.3 CDO72527.1 - 0.066 10.5 1.7 3.2 4.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) G-alpha PF00503.15 CDO72527.1 - 0.08 11.6 0.0 0.3 9.7 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit ABC_transp_aux PF09822.4 CDO72527.1 - 0.13 11.7 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Adaptin_N PF01602.15 CDO72527.1 - 0.14 10.4 1.4 0.57 8.4 1.0 1.8 1 1 0 1 1 1 0 Adaptin N terminal region KAP_NTPase PF07693.9 CDO72527.1 - 0.15 11.0 0.6 3.4 6.5 0.0 2.9 3 1 0 3 3 3 0 KAP family P-loop domain AAA_24 PF13479.1 CDO72527.1 - 0.19 11.2 1.0 8.6 5.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CDO72527.1 - 0.22 10.3 0.3 15 4.3 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 CDO72527.1 - 0.23 11.2 1.1 15 5.3 0.1 3.4 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 CDO72527.1 - 0.23 10.4 0.0 16 4.4 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain SCIMP PF15050.1 CDO72528.1 - 4.8 7.0 6.0 8 6.3 1.4 2.9 2 1 1 3 3 3 0 SCIMP protein Glyco_hydro_61 PF03443.9 CDO72529.1 - 1.8e-64 217.5 0.1 1.8e-64 217.5 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Mucin PF01456.12 CDO72529.1 - 0.0044 16.7 12.4 0.0081 15.9 8.6 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein Homeobox PF00046.24 CDO72530.1 - 3.9e-17 61.6 3.9 6.9e-17 60.8 2.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CDO72530.1 - 0.00018 21.1 0.3 0.00077 19.1 0.0 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 CDO72530.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Pkinase PF00069.20 CDO72531.1 - 6.3e-17 61.5 0.0 9.2e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO72531.1 - 6.4e-06 25.4 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDO72532.1 - 1.2e-16 60.6 0.0 1.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO72532.1 - 1.6e-06 27.3 0.0 2.3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CDO72532.1 - 0.008 16.6 0.0 0.021 15.3 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Glyco_hydro_18 PF00704.23 CDO72533.1 - 9.7e-95 317.8 0.9 1.2e-94 317.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 CDO72533.1 - 1.1e-12 47.3 12.1 2e-12 46.5 8.4 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain Phage_CII PF05269.6 CDO72533.1 - 0.09 12.7 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage CII protein DUF3142 PF11340.3 CDO72533.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) SSP160 PF06933.6 CDO72533.1 - 9.7 4.0 12.3 14 3.4 8.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 GTP_EFTU PF00009.22 CDO72535.1 - 1.9e-21 76.3 0.0 3.2e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CDO72535.1 - 2.9e-05 24.0 0.2 9.8e-05 22.3 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MobB PF03205.9 CDO72535.1 - 0.04 13.6 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 CDO72535.1 - 0.087 12.3 0.2 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein zf-RING_2 PF13639.1 CDO72536.1 - 1.9e-11 43.6 2.0 4.1e-09 36.1 0.4 2.4 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 CDO72536.1 - 6e-07 29.4 3.0 1.7e-05 24.8 2.1 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDO72536.1 - 1.9e-06 27.3 0.2 2.2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO72536.1 - 2.2e-06 27.5 2.4 4.7e-06 26.5 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO72536.1 - 4.8e-05 22.9 0.7 0.00012 21.7 0.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CDO72536.1 - 0.00038 20.0 1.3 0.00086 18.9 0.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDO72536.1 - 0.00055 19.7 0.3 0.0027 17.5 0.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 CDO72536.1 - 0.0065 16.4 0.8 0.012 15.5 0.5 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_4 PF14570.1 CDO72536.1 - 0.08 12.5 0.1 0.08 12.5 0.1 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CDO72536.1 - 0.24 11.3 1.8 0.59 10.0 0.4 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF3169 PF11368.3 CDO72536.1 - 0.28 10.3 2.0 9.6 5.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) PHD PF00628.24 CDO72536.1 - 0.38 10.4 1.5 0.88 9.3 1.0 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 CDO72536.1 - 0.45 10.5 4.7 0.7 9.8 1.2 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain DUF3415 PF11895.3 CDO72537.1 - 1.3e-36 124.2 5.0 2.1e-36 123.6 1.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 CDO72537.1 - 2.5e-29 102.4 0.0 4.2e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 CDO72538.1 - 1.8e-34 117.4 2.7 4.2e-34 116.2 1.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 CDO72538.1 - 6.2e-24 84.7 0.0 1.2e-23 83.8 0.0 1.5 1 1 0 1 1 1 1 Peroxidase Stonin2_N PF12016.3 CDO72538.1 - 0.051 12.7 3.9 0.072 12.2 2.7 1.2 1 0 0 1 1 1 0 Stonin 2 DUF3415 PF11895.3 CDO72539.1 - 2.5e-34 117.0 2.5 6.4e-34 115.6 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 CDO72539.1 - 5.6e-21 75.0 0.1 1.3e-20 73.8 0.0 1.6 2 0 0 2 2 2 1 Peroxidase DUF3415 PF11895.3 CDO72540.1 - 1.6e-32 111.2 0.4 3.2e-32 110.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 CDO72540.1 - 1.5e-21 76.9 0.0 2.1e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Peptidase_C1_2 PF03051.10 CDO72541.1 - 1.4e-158 527.9 0.0 1.7e-158 527.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 CDO72541.1 - 5.8e-07 29.6 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.8 CDO72541.1 - 0.0027 16.3 0.0 0.0041 15.6 0.0 1.2 1 0 0 1 1 1 1 Phage portal protein, lambda family DUF4218 PF13960.1 CDO72542.1 - 3.7e-05 23.1 0.1 6e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF3457 PF11939.3 CDO72542.1 - 0.063 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3457) Transposase_21 PF02992.9 CDO72543.1 - 6.7e-16 58.0 0.0 6.2e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 CDO72543.1 - 0.004 16.5 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF605 PF04652.11 CDO72543.1 - 2.8 7.2 8.7 5.2 6.3 6.0 1.3 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 CDO72543.1 - 3 5.7 9.4 4.2 5.2 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CDO72543.1 - 7.9 4.8 10.7 11 4.3 7.4 1.1 1 0 0 1 1 1 0 Daxx Family rve PF00665.21 CDO72546.1 - 1.1e-07 32.0 0.0 2.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CDO72546.1 - 0.038 13.9 0.1 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 DDE domain DUF331 PF03889.8 CDO72546.1 - 0.13 11.5 0.2 0.32 10.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function zf-CCHC PF00098.18 CDO72547.1 - 2.5e-05 23.9 2.3 4.2e-05 23.2 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDO72547.1 - 0.032 13.8 0.3 0.066 12.8 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDO72547.1 - 0.056 13.1 0.6 0.1 12.2 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_60s PF00428.14 CDO72547.1 - 0.1 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein APH PF01636.18 CDO72548.1 - 0.00078 19.2 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 CDO72548.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase ARD PF03079.9 CDO72549.1 - 2.6e-39 134.6 0.0 3.7e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 CDO72549.1 - 2.3e-10 39.8 0.1 4.2e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CDO72549.1 - 9.3e-07 28.6 0.3 1.4e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Sugar_tr PF00083.19 CDO72549.1 - 5e-06 25.3 0.1 6.7e-06 24.9 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Cupin_1 PF00190.17 CDO72549.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 CDO72549.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Cupin-like domain DUF1498 PF07385.7 CDO72549.1 - 0.14 11.2 0.1 7.8 5.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1498) WD40 PF00400.27 CDO72551.1 - 2.4e-40 134.9 35.8 1.5e-09 37.3 0.0 10.9 12 0 0 12 12 12 6 WD domain, G-beta repeat NACHT PF05729.7 CDO72551.1 - 3.4e-12 46.3 0.0 2.2e-11 43.7 0.0 2.4 3 1 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 CDO72551.1 - 7.9e-05 22.8 0.0 0.00024 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDO72551.1 - 0.00014 21.9 0.5 0.00051 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 CDO72551.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PD40 PF07676.7 CDO72551.1 - 0.029 14.0 2.2 21 4.8 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 CDO72551.1 - 0.14 10.4 0.0 1.5 7.0 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain KAP_NTPase PF07693.9 CDO72551.1 - 0.32 9.9 0.1 0.59 9.0 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Coatomer_WDAD PF04053.9 CDO72551.1 - 0.47 9.1 0.0 1.3 7.7 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region IKI3 PF04762.7 CDO72551.1 - 0.55 7.9 0.4 2.1 6.0 0.0 1.9 2 0 0 2 2 2 0 IKI3 family WD40 PF00400.27 CDO72552.1 - 1.4e-49 164.2 30.4 3.2e-11 42.6 0.1 10.7 10 0 0 10 10 10 7 WD domain, G-beta repeat NACHT PF05729.7 CDO72552.1 - 1e-10 41.5 0.1 2.7e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 CDO72552.1 - 3.9e-06 27.0 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Nup160 PF11715.3 CDO72552.1 - 4.3e-05 21.8 1.9 0.067 11.3 0.2 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 AAA_16 PF13191.1 CDO72552.1 - 6e-05 23.1 0.0 6e-05 23.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 CDO72552.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Coatomer_WDAD PF04053.9 CDO72552.1 - 0.035 12.8 0.0 0.27 9.9 0.0 2.3 4 0 0 4 4 4 0 Coatomer WD associated region AAA_30 PF13604.1 CDO72552.1 - 0.051 13.1 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 CDO72552.1 - 0.15 11.0 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain APS_kinase PF01583.15 CDO72552.1 - 0.23 11.1 0.0 0.4 10.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase zf-met PF12874.2 CDO72553.1 - 0.0034 17.5 0.4 0.011 15.8 0.3 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CDO72553.1 - 0.016 15.3 0.4 0.048 13.8 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CDO72553.1 - 0.34 10.8 5.4 0.17 11.8 1.6 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Cnd1_N PF12922.2 CDO72557.1 - 2.1e-49 167.4 0.9 4e-49 166.5 0.4 1.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term FKS1_dom1 PF14288.1 CDO72557.1 - 0.024 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Transposase_21 PF02992.9 CDO72558.1 - 3.8e-09 35.9 0.0 9e-09 34.7 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO72558.1 - 0.1 12.0 0.2 0.21 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) WD40 PF00400.27 CDO72559.1 - 2.4e-44 147.6 24.8 5.4e-09 35.6 0.2 11.3 12 0 0 12 12 12 8 WD domain, G-beta repeat NACHT PF05729.7 CDO72559.1 - 1.8e-10 40.7 0.0 1.2e-09 38.0 0.0 2.4 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 CDO72559.1 - 3.8e-05 23.7 0.9 0.00013 22.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CDO72559.1 - 0.0005 20.2 0.0 0.0016 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CDO72559.1 - 0.0014 17.5 0.0 0.0033 16.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 CDO72559.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Coatomer_WDAD PF04053.9 CDO72559.1 - 0.051 12.3 0.0 4.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Coatomer WD associated region PD40 PF07676.7 CDO72559.1 - 0.078 12.6 0.1 1 9.0 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat AAA PF00004.24 CDO72559.1 - 0.2 11.8 0.0 3.6 7.8 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3337 PF11816.3 CDO72560.1 - 3.7e-44 151.4 0.0 4.4e-42 144.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 CDO72560.1 - 9.9e-31 104.4 14.0 4.1e-08 32.8 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Squash PF00299.13 CDO72561.1 - 0.038 13.8 0.2 0.071 12.9 0.1 1.5 1 0 0 1 1 1 0 Squash family serine protease inhibitor Prokineticin PF06607.6 CDO72561.1 - 0.17 12.0 0.8 0.22 11.6 0.5 1.4 1 1 0 1 1 1 0 Prokineticin WAP PF00095.16 CDO72561.1 - 0.24 11.3 2.2 0.22 11.5 1.1 1.4 1 1 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' ACI44 PF15270.1 CDO72561.1 - 0.43 10.6 2.7 0.59 10.1 1.9 1.3 1 1 0 1 1 1 0 Metallo-carboxypeptidase inhibitor DX PF01666.12 CDO72562.1 - 0.012 16.0 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 DX module NACHT PF05729.7 CDO72564.1 - 0.0046 16.6 0.2 0.0096 15.5 0.1 1.5 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 CDO72564.1 - 0.062 12.2 0.0 0.16 10.9 0.0 1.7 1 0 0 1 1 1 0 KAP family P-loop domain APH PF01636.18 CDO72565.1 - 0.0004 20.2 0.0 0.00074 19.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 CDO72565.1 - 0.015 14.3 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase HMG_box_5 PF14887.1 CDO72565.1 - 0.098 12.4 0.3 0.3 10.9 0.2 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Sugar_tr PF00083.19 CDO72566.1 - 1.7e-27 96.1 7.4 8.8e-14 50.9 1.8 3.0 2 1 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 CDO72566.1 - 0.0029 16.3 6.9 0.47 9.1 3.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily LamB_YcsF PF03746.11 CDO72567.1 - 2.9e-63 213.2 0.0 3.3e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family APH PF01636.18 CDO72568.1 - 0.00051 19.8 0.4 0.00096 18.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 CDO72568.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase NUC173 PF08161.7 CDO72568.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 NUC173 domain LamB_YcsF PF03746.11 CDO72569.1 - 1.5e-06 27.4 0.0 1.8e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family APH PF01636.18 CDO72570.1 - 0.00062 19.5 0.5 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 CDO72570.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Sugar_tr PF00083.19 CDO72571.1 - 6.8e-06 24.9 1.1 2.1e-05 23.3 0.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter FAD_binding_3 PF01494.14 CDO72572.1 - 1.4e-20 73.6 0.1 3.7e-20 72.2 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CDO72572.1 - 7.7e-07 29.0 1.2 2.1e-06 27.6 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 CDO72572.1 - 9.4e-07 27.8 1.2 0.0011 17.7 0.8 2.4 1 1 1 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 CDO72572.1 - 3.2e-05 23.0 1.0 0.0062 15.4 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CDO72572.1 - 0.0001 22.2 0.1 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CDO72572.1 - 0.00013 20.9 4.2 0.00017 20.5 1.9 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CDO72572.1 - 0.00053 19.1 0.2 0.00097 18.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 CDO72572.1 - 0.00074 18.4 3.6 0.0012 17.7 2.5 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 CDO72572.1 - 0.005 15.7 0.0 0.0069 15.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.19 CDO72572.1 - 0.0061 15.6 0.6 0.012 14.7 0.4 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 CDO72572.1 - 0.0083 15.2 0.5 0.012 14.7 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CDO72572.1 - 0.009 14.5 2.1 0.018 13.5 1.4 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 CDO72572.1 - 0.0091 16.3 0.6 0.028 14.8 0.4 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CDO72572.1 - 0.057 12.2 3.3 0.088 11.6 2.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 CDO72572.1 - 0.15 11.7 0.7 0.25 10.9 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CDO72572.1 - 0.17 11.5 0.5 0.26 11.0 0.3 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 CDO72572.1 - 0.28 10.6 1.6 0.47 9.8 1.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3533 PF12051.3 CDO72573.1 - 3.8e-68 229.9 14.0 4.2e-68 229.8 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) NTase_sub_bind PF08780.6 CDO72573.1 - 0.21 11.3 0.7 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like MFS_1 PF07690.11 CDO72574.1 - 2.8e-28 98.6 24.7 4.1e-28 98.0 17.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 CDO72574.1 - 0.046 14.1 0.4 0.14 12.5 0.3 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.11 CDO72575.1 - 1.4e-29 102.9 31.2 1.9e-29 102.5 21.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.16 CDO72577.1 - 0.00094 18.5 0.0 0.0025 17.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 COX7C PF02935.11 CDO72578.1 - 5.1e-10 38.9 0.4 6.8e-10 38.6 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Sfi1_C PF10638.4 CDO72579.1 - 0.17 12.3 1.9 0.4 11.1 1.3 1.6 1 0 0 1 1 1 0 Spindle body associated protein C-terminus Epimerase PF01370.16 CDO72580.1 - 6.6e-20 71.5 0.0 1.3e-19 70.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO72580.1 - 2.5e-14 52.6 0.0 4.8e-13 48.4 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CDO72580.1 - 6.2e-13 48.2 0.0 8.7e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CDO72580.1 - 2.4e-11 43.9 0.7 5.3e-06 26.5 0.1 2.5 2 1 0 2 2 2 2 NADH(P)-binding KR PF08659.5 CDO72580.1 - 0.00013 21.7 2.9 0.0012 18.5 2.0 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 CDO72580.1 - 0.00023 21.1 1.5 0.00064 19.6 1.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 CDO72580.1 - 0.01 15.1 0.4 0.033 13.4 0.2 1.9 2 1 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.10 CDO72580.1 - 0.036 12.9 0.5 0.78 8.5 0.4 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 CDO72581.1 - 3.2e-42 144.3 0.0 1.5e-40 138.9 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 CDO72581.1 - 8.4e-14 51.9 0.0 1.4e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CDO72581.1 - 2.7e-05 22.9 0.0 4.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CDO72581.1 - 6.8e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CDO72581.1 - 0.0079 16.1 1.0 0.019 14.9 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase DapB_N PF01113.15 CDO72581.1 - 0.027 14.3 0.0 0.061 13.2 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_28 PF00295.12 CDO72584.1 - 2.2e-48 164.8 15.9 5.4e-25 88.0 2.7 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 DUF4098 PF13345.1 CDO72585.1 - 0.018 14.9 3.2 1.6 8.7 0.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4098) F-box-like PF12937.2 CDO72587.1 - 2.8e-06 26.9 0.8 7.3e-06 25.6 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDO72587.1 - 0.0002 20.9 0.5 0.0045 16.6 0.0 2.8 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 CDO72587.1 - 0.018 14.6 0.6 0.4 10.3 0.2 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO72587.1 - 0.027 14.2 0.2 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat Evr1_Alr PF04777.8 CDO72588.1 - 5.4e-24 83.9 0.3 2.6e-23 81.7 0.1 2.0 2 0 0 2 2 2 1 Erv1 / Alr family TP_methylase PF00590.15 CDO72588.1 - 3.9e-11 43.0 0.0 6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases tRNA-synt_2 PF00152.15 CDO72589.1 - 5.4e-74 248.9 0.0 7.9e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CDO72589.1 - 3.8e-12 45.8 0.4 9.4e-12 44.6 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF4539 PF15072.1 CDO72589.1 - 0.086 12.5 0.0 0.27 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) DUF4164 PF13747.1 CDO72590.1 - 0.2 11.8 1.6 0.4 10.8 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Pkinase PF00069.20 CDO72593.1 - 3.7e-34 118.0 0.0 7.7e-22 77.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO72593.1 - 1.4e-19 70.2 0.0 8.1e-12 44.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase SR-25 PF10500.4 CDO72593.1 - 3.4 7.0 11.6 6.3 6.1 8.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DDE_3 PF13358.1 CDO72595.1 - 1.1e-25 90.0 0.0 1.7e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CDO72595.1 - 5.4e-10 39.1 3.7 9.4e-07 28.8 1.1 3.3 3 0 0 3 3 3 2 Transposase HTH_38 PF13936.1 CDO72595.1 - 1.7e-07 30.6 0.0 4.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CDO72595.1 - 2e-07 30.4 0.3 1.2e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CDO72595.1 - 1.7e-05 24.8 3.4 2.3e-05 24.5 1.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 CDO72595.1 - 3.4e-05 23.7 0.0 3.4e-05 23.7 0.0 2.8 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_11 PF08279.7 CDO72595.1 - 0.00021 20.8 0.1 0.0024 17.4 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_IclR PF09339.5 CDO72595.1 - 0.00026 20.5 0.0 0.00069 19.1 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.11 CDO72595.1 - 0.00087 18.5 0.0 0.0028 16.9 0.0 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 CDO72595.1 - 0.001 18.2 0.4 0.01 14.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.2 CDO72595.1 - 0.0014 18.2 1.1 0.0026 17.3 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_AraC PF00165.18 CDO72595.1 - 0.0039 16.9 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family rve PF00665.21 CDO72595.1 - 0.0057 16.7 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain GntR PF00392.16 CDO72595.1 - 0.017 14.5 0.0 0.052 13.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.10 CDO72595.1 - 0.021 14.6 0.1 2 8.3 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_24 PF13412.1 CDO72595.1 - 0.024 14.0 0.3 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 CDO72595.1 - 0.03 14.0 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 MarR family TrmB PF01978.14 CDO72595.1 - 0.035 13.8 0.0 0.099 12.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.1 CDO72595.1 - 0.041 13.4 1.1 0.27 10.8 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_20 PF12840.2 CDO72595.1 - 0.043 13.6 1.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_NinH PF06322.6 CDO72595.1 - 0.21 11.2 1.0 0.41 10.2 0.1 1.9 2 0 0 2 2 2 0 Phage NinH protein SNF2_N PF00176.18 CDO72596.1 - 8.1e-71 238.2 0.8 1.3e-70 237.5 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDO72596.1 - 8.9e-14 51.1 0.0 2.6e-12 46.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO72596.1 - 1.2e-06 28.4 0.0 3.5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CDO72596.1 - 3.7e-06 26.5 0.0 1.4e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Baculo_LEF-3 PF05847.6 CDO72596.1 - 0.28 10.0 0.2 0.47 9.3 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) ArsB PF02040.10 CDO72597.1 - 5.3e-18 65.1 20.6 6e-10 38.6 2.7 3.2 2 1 0 2 2 2 2 Arsenical pump membrane protein DUF1003 PF06210.6 CDO72597.1 - 0.067 13.1 0.3 0.067 13.1 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) Mito_carr PF00153.22 CDO72599.1 - 1.2e-36 124.2 0.1 1.7e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein Peptidase_S8 PF00082.17 CDO72604.1 - 5e-36 124.2 6.2 6.4e-36 123.9 4.3 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CDO72604.1 - 2.7e-17 63.0 0.1 5.9e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sulfate_transp PF00916.15 CDO72606.1 - 3.4e-44 150.9 1.0 3.4e-44 150.9 0.7 1.5 1 1 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 CDO72606.1 - 4e-10 39.1 0.0 2.7e-06 26.7 0.0 3.2 2 1 0 2 2 2 2 STAS domain DUF3649 PF12365.3 CDO72606.1 - 0.11 12.0 0.2 0.11 12.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3649) GPI-anchored PF10342.4 CDO72610.1 - 9.8e-05 22.7 0.0 0.00016 22.1 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CDO72610.1 - 0.044 13.2 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Cyclase PF04199.8 CDO72613.1 - 8.4e-67 224.1 1.8 4.8e-36 124.0 0.1 2.1 2 0 0 2 2 2 2 Putative cyclase Glyco_hydro_31 PF01055.21 CDO72614.1 - 6e-149 496.6 3.9 9.5e-149 495.9 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CDO72614.1 - 4.5e-19 68.0 0.2 1.1e-18 66.8 0.1 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like LRR_4 PF12799.2 CDO72616.1 - 0.13 11.9 0.6 20 4.9 0.1 3.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Helicase_C_2 PF13307.1 CDO72617.1 - 7e-52 175.7 0.0 1.3e-51 174.8 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CDO72617.1 - 9.3e-38 129.3 0.0 9.4e-32 109.7 0.0 2.4 1 1 0 2 2 2 2 DEAD_2 DEAD PF00270.24 CDO72617.1 - 0.0023 17.4 0.0 0.043 13.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 CDO72617.1 - 0.042 13.0 0.0 0.38 9.9 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Phage_lysis PF03245.8 CDO72617.1 - 0.089 12.7 5.0 0.11 12.4 2.0 2.3 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Mito_carr PF00153.22 CDO72618.1 - 2.3e-46 155.4 0.1 2.2e-15 56.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein 3HCDH_N PF02737.13 CDO72619.1 - 9.8e-51 171.9 4.2 8.5e-50 168.8 2.9 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CDO72619.1 - 4.3e-22 78.3 0.0 1.3e-21 76.7 0.0 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CDO72619.1 - 0.0074 16.1 1.0 0.021 14.6 0.7 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 CDO72619.1 - 0.013 15.2 0.2 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus polyprenyl_synt PF00348.12 CDO72621.1 - 1.2e-12 47.2 0.0 1.4e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEAT PF02985.17 CDO72622.1 - 9.6e-39 127.9 28.4 0.045 13.8 0.0 22.2 24 0 0 24 24 24 9 HEAT repeat HEAT_2 PF13646.1 CDO72622.1 - 1.8e-38 130.6 32.0 9.7e-07 28.9 0.0 14.3 11 4 3 14 14 14 9 HEAT repeats DUF3554 PF12074.3 CDO72622.1 - 2.1e-35 122.7 6.3 1.5e-34 119.9 0.0 4.5 3 2 1 5 5 5 1 Domain of unknown function (DUF3554) HEAT_EZ PF13513.1 CDO72622.1 - 2.6e-32 110.4 37.4 5.7e-06 26.6 0.1 17.1 14 4 7 21 21 20 8 HEAT-like repeat CLASP_N PF12348.3 CDO72622.1 - 1.2e-10 41.1 0.0 0.0017 17.7 0.0 6.4 4 1 1 7 7 7 2 CLASP N terminal Cnd1 PF12717.2 CDO72622.1 - 3.4e-07 30.3 0.0 7.9 6.2 0.1 7.8 8 2 1 9 9 9 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CDO72622.1 - 4.1e-07 28.7 1.5 0.26 9.5 0.1 7.1 7 3 0 7 7 7 2 Adaptin N terminal region Ecm29 PF13001.2 CDO72622.1 - 4.3e-06 25.5 0.2 0.25 9.8 0.0 5.8 6 1 1 7 7 7 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.2 CDO72622.1 - 1.2e-05 25.5 0.0 6.5 7.2 0.0 6.6 5 2 2 7 7 7 1 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 CDO72622.1 - 0.00018 21.3 2.7 0.56 10.2 0.3 4.4 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion UNC45-central PF11701.3 CDO72622.1 - 0.00058 19.5 0.7 0.021 14.4 0.0 3.4 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central UPF0146 PF03686.8 CDO72622.1 - 0.12 12.1 0.0 0.82 9.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Vitellogenin_N PF01347.17 CDO72622.1 - 0.86 7.7 0.1 69 1.4 0.0 2.9 3 0 0 3 3 3 0 Lipoprotein amino terminal region Arm PF00514.18 CDO72622.1 - 2 8.3 11.7 5.4 6.9 0.0 6.5 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat MFS_1 PF07690.11 CDO72623.1 - 8.8e-44 149.6 50.3 3.2e-40 137.9 36.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CDO72623.1 - 1e-07 30.6 12.5 1e-07 30.6 8.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CDO72623.1 - 3.5e-05 22.5 18.6 3.5e-05 22.5 12.9 3.1 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 CDO72623.1 - 7.1 6.4 11.2 0.22 11.3 2.4 2.6 3 0 0 3 3 3 0 MFS_1 like family HMG_box PF00505.14 CDO72624.1 - 0.00036 20.7 0.0 0.0011 19.2 0.0 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box GPI-anchored PF10342.4 CDO72625.1 - 0.00041 20.7 0.0 0.00058 20.2 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CDO72625.1 - 0.028 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Fanconi_A PF03511.9 CDO72625.1 - 0.076 12.8 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein YCII PF03795.9 CDO72626.1 - 2.9e-10 40.2 0.0 3.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DNA_pol_B_thumb PF14791.1 CDO72628.1 - 2.5e-20 71.9 0.0 5.3e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 CDO72628.1 - 2.9e-17 62.7 0.0 5.8e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 CDO72628.1 - 1.5e-12 47.5 0.1 9.2e-12 44.9 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 CDO72628.1 - 2.2e-09 36.6 0.0 5.4e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 CDO72628.1 - 9.1e-06 25.7 0.0 3.5e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.3 CDO72628.1 - 0.049 13.5 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 Pathogenicity locus DUF2486 PF10667.4 CDO72629.1 - 0.093 13.2 22.7 0.15 12.5 15.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) IDO PF01231.13 CDO72629.1 - 0.11 10.8 0.0 0.11 10.8 0.0 1.6 2 0 0 2 2 2 0 Indoleamine 2,3-dioxygenase Hamartin PF04388.7 CDO72629.1 - 1.1 7.8 7.9 1.5 7.4 5.5 1.1 1 0 0 1 1 1 0 Hamartin protein PBP_sp32 PF07222.7 CDO72629.1 - 1.5 7.9 12.6 2.6 7.1 8.7 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FLILHELTA PF10306.4 CDO72630.1 - 3.7e-11 42.8 0.0 7.4e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA GPI-anchored PF10342.4 CDO72631.1 - 0.00063 20.1 0.0 0.00091 19.6 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CDO72631.1 - 0.025 14.0 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Fanconi_A PF03511.9 CDO72631.1 - 0.035 13.9 0.2 0.068 12.9 0.2 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein DNA_pol_B_thumb PF14791.1 CDO72632.1 - 1.1e-20 73.0 0.0 2.3e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 CDO72632.1 - 1.9e-12 47.1 0.1 2.7e-11 43.4 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 CDO72632.1 - 6e-10 38.5 0.0 1.7e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 CDO72632.1 - 7.5e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_5 PF14520.1 CDO72632.1 - 8.8e-05 22.6 0.0 0.00028 20.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.3 CDO72632.1 - 0.0086 15.9 0.0 0.027 14.3 0.0 1.9 1 1 0 1 1 1 1 Pathogenicity locus IMS_HHH PF11798.3 CDO72632.1 - 0.039 14.0 0.0 1.9 8.7 0.0 2.8 2 0 0 2 2 2 0 IMS family HHH motif Paramyxo_ncap PF00973.14 CDO72634.1 - 0.69 8.5 10.0 1.2 7.7 7.0 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein FAM60A PF15396.1 CDO72634.1 - 1.6 8.4 10.3 2.9 7.5 7.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A OmpH PF03938.9 CDO72634.1 - 2.5 8.0 11.9 4.7 7.1 8.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3138 PF11336.3 CDO72634.1 - 3.4 5.7 7.1 0.25 9.4 1.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Bap31 PF05529.7 CDO72634.1 - 4.9 6.5 7.7 9.9 5.5 5.3 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like UBN2_2 PF14227.1 CDO72635.1 - 2e-09 37.0 0.0 7.5e-09 35.1 0.0 1.8 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO72635.1 - 2.4e-07 30.5 0.0 3.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO72635.1 - 2e-05 24.1 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO72635.1 - 2.4e-05 23.6 1.0 3.3e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotrans_gag PF03732.12 CDO72635.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 Retrotransposon gag protein DDE_3 PF13358.1 CDO72637.1 - 5.6e-11 42.3 0.0 8.2e-06 25.6 0.0 2.7 2 0 0 2 2 2 2 DDE superfamily endonuclease Acyl-CoA_dh_1 PF00441.19 CDO72638.1 - 2.1e-26 92.8 0.2 3e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CDO72638.1 - 6.7e-22 76.7 0.3 2.9e-21 74.7 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CDO72638.1 - 8.2e-07 29.3 0.1 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CDO72638.1 - 1.1e-05 25.9 0.0 2.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Allexi_40kDa PF05549.6 CDO72639.1 - 0.007 15.6 1.7 0.011 15.0 1.2 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein COG5 PF10392.4 CDO72639.1 - 0.011 15.6 1.2 0.02 14.8 0.8 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Erp_C PF06780.6 CDO72639.1 - 0.06 13.1 1.8 0.11 12.3 1.3 1.3 1 0 0 1 1 1 0 Erp protein C-terminus HemX PF04375.9 CDO72639.1 - 0.077 11.5 5.8 0.12 10.9 4.0 1.2 1 0 0 1 1 1 0 HemX DUF3389 PF11869.3 CDO72639.1 - 0.098 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3389) DUF342 PF03961.8 CDO72639.1 - 0.12 10.7 2.7 0.16 10.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 CDO72639.1 - 0.32 10.0 6.3 0.48 9.4 4.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Snapin_Pallidin PF14712.1 CDO72639.1 - 0.55 10.5 5.0 4.2 7.7 0.1 2.6 1 1 0 2 2 2 0 Snapin/Pallidin Prefoldin PF02996.12 CDO72639.1 - 0.85 9.2 8.7 0.33 10.6 1.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit Rho_Binding PF08912.6 CDO72639.1 - 0.98 9.7 8.8 1.3 9.3 1.5 2.7 3 0 0 3 3 2 0 Rho Binding CENP-F_leu_zip PF10473.4 CDO72639.1 - 1.2 8.9 13.1 0.71 9.7 6.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_23 PF13476.1 CDO72639.1 - 2.9 8.1 5.3 5.2 7.3 3.6 1.3 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 CDO72639.1 - 3.1 8.3 9.9 11 6.4 3.6 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 CDO72639.1 - 3.9 7.0 13.4 18 4.8 9.3 1.9 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 CDO72639.1 - 4 6.2 8.5 6.3 5.6 5.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mod_r PF07200.8 CDO72639.1 - 6.2 6.7 10.8 28 4.6 6.8 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF972 PF06156.8 CDO72639.1 - 7.3 6.9 11.9 11 6.4 2.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) YCII PF03795.9 CDO72640.1 - 1.9e-08 34.3 0.0 2.3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Fe-S_biosyn PF01521.15 CDO72641.1 - 1.1e-12 47.8 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis bZIP_1 PF00170.16 CDO72645.1 - 1.3e-08 34.6 12.3 1.3e-08 34.6 8.5 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CDO72645.1 - 3.2e-07 30.0 12.6 3.2e-07 30.0 8.7 2.5 2 1 0 2 2 2 1 Basic region leucine zipper Tropomodulin PF03250.9 CDO72645.1 - 0.15 11.5 3.8 0.29 10.6 2.6 1.4 1 1 0 1 1 1 0 Tropomodulin DUF342 PF03961.8 CDO72645.1 - 1.6 7.0 5.8 2.5 6.4 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Acetyltransf_6 PF13480.1 CDO72645.1 - 2.2 8.2 5.3 4.5 7.2 3.6 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TSC22 PF01166.13 CDO72645.1 - 9.3 6.3 8.6 19 5.3 0.9 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family ABC_membrane PF00664.18 CDO72646.1 - 1.2e-47 162.6 4.6 1.6e-47 162.2 3.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CDO72646.1 - 2.3e-31 108.9 0.0 6.4e-31 107.4 0.0 1.8 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 CDO72646.1 - 2.4e-06 26.9 0.1 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDO72646.1 - 0.00054 20.0 0.0 0.0095 15.9 0.0 2.2 1 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CDO72646.1 - 0.0034 16.4 0.0 0.011 14.8 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 CDO72646.1 - 0.0093 15.9 0.1 0.035 14.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CDO72646.1 - 0.015 14.8 0.0 0.042 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CDO72646.1 - 0.027 13.6 0.1 0.069 12.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 CDO72646.1 - 0.029 15.1 0.0 0.09 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CDO72646.1 - 0.032 14.1 0.4 0.16 11.9 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CDO72646.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_22 PF13401.1 CDO72646.1 - 0.14 12.3 0.1 0.7 10.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain YCII PF03795.9 CDO72647.1 - 3e-09 36.9 0.0 4.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.9 CDO72648.1 - 6.6e-08 32.6 0.0 9.1e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain MgtE_N PF03448.12 CDO72649.1 - 0.013 15.7 1.6 0.018 15.3 1.1 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain RAP-1 PF03085.10 CDO72649.1 - 0.12 11.6 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mac-1 PF09028.5 CDO72649.1 - 0.15 10.8 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Mac 1 ARGLU PF15346.1 CDO72649.1 - 0.26 11.0 4.2 0.4 10.4 2.9 1.4 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 LRV PF01816.12 CDO72649.1 - 0.53 10.5 2.8 25 5.3 1.9 2.3 1 1 0 1 1 1 0 Leucine rich repeat variant CTP_transf_2 PF01467.21 CDO72652.1 - 2.7e-27 95.7 0.0 3.4e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Amidohydro_1 PF01979.15 CDO72653.1 - 1.6e-14 54.3 0.0 1.7e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CDO72653.1 - 8.6e-10 39.1 0.0 9.6e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CDO72653.1 - 9.3e-09 34.9 0.0 9.3e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CDO72654.1 - 3.4e-06 26.7 0.0 7.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CDO72654.1 - 7.2e-05 22.9 0.0 8.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CDO72654.1 - 0.0003 20.5 0.0 0.00031 20.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Kri1_C PF12936.2 CDO72656.1 - 4.2e-28 97.1 0.1 4.2e-28 97.1 0.1 5.0 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 CDO72656.1 - 8.1e-24 83.8 6.4 8.1e-24 83.8 4.4 6.4 5 2 1 6 6 6 2 KRI1-like family F-box PF00646.28 CDO72657.1 - 0.006 16.2 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain Condensation PF00668.15 CDO72659.1 - 0.041 12.7 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Condensation domain WES_acyltransf PF03007.11 CDO72659.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.7 1 1 1 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.7 CDO72659.1 - 0.16 10.4 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase TEA PF01285.13 CDO72661.1 - 6.8e-16 58.4 0.3 1.3e-15 57.4 0.2 1.4 1 0 0 1 1 1 1 TEA/ATTS domain family DUF4246 PF14033.1 CDO72662.1 - 1.2e-115 387.0 0.0 6e-67 226.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) MAGE PF01454.14 CDO72663.1 - 6.5e-37 126.7 0.0 7.4e-34 116.8 0.0 2.1 2 0 0 2 2 2 2 MAGE family Adeno_terminal PF02459.10 CDO72663.1 - 1.2 7.2 6.0 1.8 6.6 4.1 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein CENP-B_dimeris PF09026.5 CDO72663.1 - 8.8 6.6 10.7 32 4.8 0.1 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Pantoate_transf PF02548.10 CDO72664.1 - 6.2e-105 350.0 0.8 7.3e-105 349.7 0.5 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 CDO72664.1 - 9.2e-12 44.6 0.6 3.3e-11 42.8 0.1 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DeoC PF01791.4 CDO72664.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 DeoC/LacD family aldolase F-box-like_2 PF13013.1 CDO72665.1 - 0.036 13.7 0.1 0.56 9.9 0.0 2.6 2 1 0 2 2 2 0 F-box-like domain APG12 PF04110.8 CDO72667.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 NmrA PF05368.8 CDO72668.1 - 1.8e-34 119.0 0.0 2.5e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CDO72668.1 - 1.8e-11 44.3 0.2 3.2e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CDO72668.1 - 0.00052 18.8 0.0 0.00079 18.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CDO72668.1 - 0.00069 19.9 0.1 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 CDO72668.1 - 0.039 13.3 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.5 CDO72668.1 - 0.068 12.8 1.3 0.085 12.5 0.1 1.7 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 CDO72668.1 - 0.77 9.6 3.0 0.51 10.2 0.4 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Ceramidase_alk PF04734.8 CDO72669.1 - 1.2e-237 790.1 0.2 1.1e-236 786.9 0.1 1.9 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase His_Phos_2 PF00328.17 CDO72670.1 - 4.2e-08 32.9 0.0 8.7e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SRP72 PF08492.7 CDO72671.1 - 9.8e-10 38.6 2.5 9.8e-10 38.6 1.7 1.8 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_16 PF13432.1 CDO72671.1 - 7.3e-09 36.0 16.1 8.4e-05 23.1 4.9 2.9 3 1 0 3 3 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CDO72671.1 - 1.5e-08 34.6 5.7 5e-05 23.3 0.3 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CDO72671.1 - 1.1e-06 28.0 7.6 0.0044 16.8 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CDO72671.1 - 1.2e-06 28.0 4.2 0.0071 15.9 0.1 3.0 3 0 0 3 3 3 2 TPR repeat TPR_15 PF13429.1 CDO72671.1 - 7.8e-05 21.8 4.9 0.0042 16.1 1.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO72671.1 - 8.1e-05 22.9 12.8 0.075 13.7 0.0 4.1 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO72671.1 - 0.00011 22.5 16.2 0.007 16.6 0.2 3.7 2 1 1 4 4 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 CDO72671.1 - 0.00061 20.0 2.9 0.086 13.3 0.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDO72671.1 - 0.00099 18.6 2.8 0.38 10.4 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDO72671.1 - 0.0097 15.7 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 CDO72671.1 - 0.018 14.8 7.4 0.086 12.7 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDO72671.1 - 0.023 14.4 4.5 0.11 12.3 0.3 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CDO72671.1 - 0.042 14.0 1.3 0.41 10.8 0.3 2.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_12 PF13424.1 CDO72671.1 - 0.051 13.5 10.0 0.03 14.2 4.1 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 CDO72671.1 - 0.072 12.5 0.2 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) APG6 PF04111.7 CDO72671.1 - 0.23 10.4 2.0 0.31 10.0 1.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_10 PF13374.1 CDO72671.1 - 2.3 8.2 7.1 0.46 10.4 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4381 PF14316.1 CDO72672.1 - 0.0047 17.0 0.1 0.0068 16.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) Herpes_gE PF02480.11 CDO72672.1 - 0.013 13.8 0.3 0.017 13.4 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rax2 PF12768.2 CDO72672.1 - 0.044 12.9 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity HAD PF12710.2 CDO72672.1 - 0.078 13.1 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DRIM PF07539.7 CDO72673.1 - 2.3e-33 114.6 0.1 7.4e-33 112.9 0.0 2.0 1 0 0 1 1 1 1 Down-regulated in metastasis Dynamin_M PF01031.15 CDO72673.1 - 1.5e-22 79.7 0.0 6.8e-16 57.8 0.0 2.9 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 CDO72673.1 - 6.7e-12 45.5 0.0 8.9e-11 41.8 0.0 2.6 2 0 0 2 2 2 1 Dynamin family HEAT PF02985.17 CDO72673.1 - 0.00036 20.3 5.4 15 5.9 0.0 7.2 7 0 0 7 7 7 1 HEAT repeat GED PF02212.13 CDO72673.1 - 0.0066 16.3 0.1 0.054 13.3 0.0 2.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain HEAT_EZ PF13513.1 CDO72673.1 - 0.082 13.4 0.0 0.082 13.4 0.0 7.8 9 0 0 9 9 9 0 HEAT-like repeat Condensin2nSMC PF12422.3 CDO72673.1 - 0.13 12.0 5.6 41 3.8 0.1 5.1 5 0 0 5 5 5 0 Condensin II non structural maintenance of chromosomes subunit Sugar_tr PF00083.19 CDO72674.1 - 3.4e-120 401.6 26.7 3.9e-120 401.4 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO72674.1 - 2.9e-18 65.7 42.2 6.4e-14 51.4 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3953 PF13129.1 CDO72674.1 - 0.018 14.6 0.4 0.018 14.6 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3953) DUF2107 PF09880.4 CDO72674.1 - 0.036 13.9 1.3 0.13 12.1 0.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2107) TPR_19 PF14559.1 CDO72674.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.19 CDO72675.1 - 1.9e-121 405.7 19.6 2.2e-121 405.5 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO72675.1 - 7.3e-21 74.2 38.9 4.8e-18 64.9 7.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_11 PF13086.1 CDO72676.1 - 4.6e-16 59.1 0.0 1.8e-08 34.2 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CDO72676.1 - 1.3e-14 54.2 0.0 1.6e-13 50.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 CDO72676.1 - 7e-14 51.6 0.0 1.8e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO72676.1 - 2.9e-11 42.9 0.0 1.6e-10 40.6 0.0 2.2 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 CDO72676.1 - 4.8e-05 23.4 0.0 9.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 CDO72676.1 - 0.00062 19.3 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 CDO72676.1 - 0.00066 18.9 0.0 0.0022 17.2 0.0 1.8 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.1 CDO72676.1 - 0.00076 19.6 0.0 0.0032 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CDO72676.1 - 0.0011 18.6 0.1 0.29 10.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 CDO72676.1 - 0.0052 17.5 1.3 0.016 16.0 0.3 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 CDO72676.1 - 0.0056 16.8 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CDO72676.1 - 0.0062 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 CDO72676.1 - 0.013 15.1 0.0 0.057 13.0 0.0 1.9 1 1 0 1 1 1 0 Helicase T2SE PF00437.15 CDO72676.1 - 0.021 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 CDO72676.1 - 0.035 13.5 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain UvrD-helicase PF00580.16 CDO72676.1 - 0.041 13.1 0.0 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain MobB PF03205.9 CDO72676.1 - 0.076 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 CDO72676.1 - 0.088 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CDO72676.1 - 0.093 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Herpes_gE PF02480.11 CDO72677.1 - 0.0036 15.6 0.0 0.01 14.1 0.0 1.8 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 CDO72677.1 - 0.018 14.7 0.0 0.018 14.7 0.0 2.9 3 0 0 3 3 3 0 TMEM154 protein family EphA2_TM PF14575.1 CDO72677.1 - 0.02 15.2 1.0 0.026 14.8 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.1 CDO72677.1 - 0.035 13.8 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 FAM176 family LRRC37AB_C PF14914.1 CDO72677.1 - 0.16 11.3 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain CPL PF08144.6 CDO72678.1 - 0.083 12.7 0.2 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 CPL (NUC119) domain GRAB PF10375.4 CDO72678.1 - 6 6.7 5.8 3.5 7.5 0.2 2.9 2 1 0 2 2 2 0 GRIP-related Arf-binding domain TMEM171 PF15471.1 CDO72679.1 - 0.23 10.1 3.5 0.25 10.1 2.4 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF1517 PF07466.6 CDO72679.1 - 0.91 8.4 4.0 1 8.3 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Pinin_SDK_memA PF04696.8 CDO72680.1 - 8e-11 41.6 9.1 8e-11 41.6 6.3 3.9 3 1 1 4 4 4 2 pinin/SDK/memA/ protein conserved region DUF1640 PF07798.6 CDO72680.1 - 3.9 7.4 10.9 6.3 6.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) CTK3 PF12243.3 CDO72681.1 - 1.9e-42 144.1 0.0 2.5e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 CDO72681.1 - 2.4e-13 49.9 17.0 3e-12 46.3 11.8 2.3 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Ter PF05472.6 CDO72681.1 - 0.17 10.9 0.2 0.25 10.4 0.1 1.2 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) Flavin_Reduct PF01613.13 CDO72682.1 - 5e-22 78.4 0.1 7.4e-22 77.8 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain RNA_pol_A_bac PF01000.21 CDO72683.1 - 9.1e-24 83.7 0.0 1.7e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CDO72683.1 - 3.7e-15 54.7 0.0 5.3e-15 54.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain AAA_12 PF13087.1 CDO72684.1 - 1.1e-26 93.4 0.1 2.9e-26 92.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDO72684.1 - 5e-20 72.0 0.0 2.7e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CDO72684.1 - 3.1e-17 62.8 0.0 5.1e-16 58.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDO72684.1 - 6.6e-10 38.6 0.0 8e-09 35.1 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 CDO72684.1 - 4.4e-05 22.8 0.0 0.021 14.0 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Viral_helicase1 PF01443.13 CDO72684.1 - 6.7e-05 22.5 0.3 0.97 8.9 0.2 3.2 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CDO72684.1 - 0.00014 22.0 0.0 0.019 15.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CDO72684.1 - 0.00051 20.0 0.0 0.0025 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 CDO72684.1 - 0.0014 17.5 0.0 0.025 13.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.4 CDO72684.1 - 0.0015 17.5 0.1 0.45 9.4 0.0 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 CDO72684.1 - 0.0022 18.2 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CDO72684.1 - 0.0031 17.1 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 CDO72684.1 - 0.0054 16.6 0.0 0.023 14.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDO72684.1 - 0.0081 16.9 0.0 0.03 15.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain Helicase_RecD PF05127.9 CDO72684.1 - 0.021 14.4 0.0 0.73 9.4 0.0 2.8 2 1 0 2 2 2 0 Helicase NTPase_1 PF03266.10 CDO72684.1 - 0.095 12.4 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 NTPase ResIII PF04851.10 CDO72684.1 - 0.13 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CDO72684.1 - 0.27 11.5 0.1 0.62 10.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain Peptidase_S28 PF05577.7 CDO72685.1 - 5.4e-45 153.7 2.7 1.9e-44 151.9 1.9 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CDO72685.1 - 4.5e-06 26.7 0.2 1e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CDO72685.1 - 0.0011 18.2 0.2 0.002 17.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDO72685.1 - 0.0022 17.7 0.1 0.0048 16.6 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO72685.1 - 0.025 14.1 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold CFEM PF05730.6 CDO72686.1 - 9.6e-07 28.5 10.7 2.1e-06 27.4 7.4 1.5 1 0 0 1 1 1 1 CFEM domain Dus PF01207.12 CDO72687.1 - 2.8e-25 88.8 0.0 3.1e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) G-alpha PF00503.15 CDO72689.1 - 1.3e-123 412.5 1.1 1.6e-123 412.2 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CDO72689.1 - 5e-14 51.9 0.2 2.5e-08 33.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO72689.1 - 0.00029 20.0 0.1 0.55 9.3 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CDO72689.1 - 0.0048 17.3 0.1 0.16 12.4 0.0 2.8 4 0 0 4 4 4 1 Miro-like protein GTP_EFTU PF00009.22 CDO72689.1 - 0.033 13.6 0.3 3 7.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 CDO72689.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CDO72689.1 - 0.073 13.0 0.0 1 9.3 0.0 2.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase VitK2_biosynth PF02621.9 CDO72691.1 - 4 6.5 5.7 5.3 6.1 3.9 1.1 1 0 0 1 1 1 0 Menaquinone biosynthesis Macoilin PF09726.4 CDO72691.1 - 4.7 5.3 7.7 5.5 5.1 5.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1236 PF06823.7 CDO72692.1 - 0.079 12.6 1.0 0.21 11.3 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1236) Nitroreductase PF00881.19 CDO72693.1 - 2.9e-16 59.7 0.0 3.5e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF1801 PF08818.6 CDO72693.1 - 0.047 13.7 0.1 0.18 11.8 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DU1801) FAM60A PF15396.1 CDO72694.1 - 0.17 11.5 1.7 0.23 11.1 1.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Methyltransf_2 PF00891.13 CDO72696.1 - 4.1e-22 78.5 0.0 9.1e-22 77.4 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_18 PF12847.2 CDO72696.1 - 0.0059 17.1 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO72696.1 - 0.13 12.7 0.0 0.42 11.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 CDO72696.1 - 0.21 10.7 0.1 0.42 9.7 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G 4HBT PF03061.17 CDO72697.1 - 2.4e-10 40.3 0.0 4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Macoilin PF09726.4 CDO72698.1 - 8.3 4.5 7.6 8.7 4.4 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF966 PF06136.8 CDO72699.1 - 7 5.9 11.1 8.5 5.6 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.4 CDO72699.1 - 7.8 4.6 7.5 9.1 4.4 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Macoilin PF09726.4 CDO72701.1 - 7.7 4.6 17.8 8.4 4.5 12.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Pyr_redox_3 PF13738.1 CDO72702.1 - 3.9e-16 59.7 0.0 6.7e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO72702.1 - 2.1e-08 34.0 0.0 5.1e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 CDO72702.1 - 6.8e-07 27.8 0.3 0.0006 18.1 0.1 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 CDO72702.1 - 1.5e-05 24.8 0.2 0.0048 16.6 0.0 3.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 CDO72702.1 - 0.00018 20.6 0.0 0.00036 19.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 CDO72702.1 - 0.00028 19.9 0.3 0.058 12.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CDO72702.1 - 0.0003 20.7 0.0 0.001 19.0 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CDO72702.1 - 0.018 13.9 0.1 0.028 13.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 CDO72702.1 - 0.027 13.3 0.0 0.18 10.6 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase RVT_1 PF00078.22 CDO72703.1 - 3.8e-16 59.0 0.0 7e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO72703.1 - 7.2e-15 55.4 0.0 1.8e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 CDO72703.1 - 1.1e-05 25.0 0.2 5e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CDO72703.1 - 0.024 14.9 0.1 0.091 13.0 0.0 2.0 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase HNH_2 PF13391.1 CDO72705.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease EF_assoc_2 PF08356.7 CDO72705.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 EF hand associated Methyltransf_2 PF00891.13 CDO72708.1 - 5.1e-24 84.8 0.8 4.6e-23 81.6 0.4 2.4 2 1 0 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 CDO72708.1 - 0.0046 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO72708.1 - 0.015 15.8 0.0 0.035 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CDO72708.1 - 0.018 14.4 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Renin_r PF07850.9 CDO72708.1 - 0.15 12.3 0.0 0.43 10.9 0.0 1.7 2 0 0 2 2 2 0 Renin receptor-like protein Aminotran_5 PF00266.14 CDO72710.1 - 2.7e-29 102.0 0.0 7.7e-23 80.8 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V MFS_1 PF07690.11 CDO72715.1 - 2e-28 99.1 36.0 3.7e-28 98.2 25.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily HCV_NS4b PF01001.14 CDO72715.1 - 0.04 13.3 5.1 0.091 12.1 0.7 2.8 2 1 1 3 3 3 0 Hepatitis C virus non-structural protein NS4b Methyltransf_2 PF00891.13 CDO72716.1 - 1.5e-13 50.5 0.0 7.9e-11 41.5 0.0 2.4 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_18 PF12847.2 CDO72716.1 - 0.0014 19.1 0.0 0.0058 17.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CDO72716.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain HEAT_EZ PF13513.1 CDO72717.1 - 0.00064 20.1 8.5 7.8 7.1 0.0 6.1 5 1 1 6 6 6 3 HEAT-like repeat HEAT PF02985.17 CDO72717.1 - 0.0099 15.8 14.6 5.3 7.3 0.0 7.4 9 0 0 9 9 9 2 HEAT repeat MMS19_C PF12460.3 CDO72717.1 - 0.024 13.3 0.1 0.2 10.3 0.0 2.2 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal zf-C2H2 PF00096.21 CDO72719.1 - 0.035 14.4 0.7 0.11 12.8 0.5 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO72719.1 - 0.35 11.3 3.6 0.32 11.4 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger CBM_14 PF01607.19 CDO72722.1 - 0.049 13.5 1.4 0.12 12.3 0.9 1.5 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain DUF4399 PF14347.1 CDO72722.1 - 0.073 13.0 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4399) GHMP_kinases_N PF00288.21 CDO72723.1 - 2.5e-12 46.6 0.0 4.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CDO72723.1 - 0.011 15.8 0.0 0.04 14.1 0.0 2.0 2 0 0 2 2 2 0 GHMP kinases C terminal Dynein_heavy PF03028.10 CDO72724.1 - 1.8e-179 598.1 1.1 6.4e-179 596.3 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CDO72724.1 - 2.7e-132 441.1 7.5 2.7e-132 441.1 5.2 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDO72724.1 - 9.3e-79 264.1 0.0 2.4e-78 262.8 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CDO72724.1 - 2.7e-47 160.5 0.0 9.6e-47 158.7 0.0 2.0 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CDO72724.1 - 4.3e-45 153.7 0.1 7.7e-44 149.6 0.1 2.5 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 CDO72724.1 - 3.1e-42 144.5 7.1 5.6e-42 143.7 4.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CDO72724.1 - 7.1e-28 97.0 0.0 1.8e-10 40.6 0.0 6.5 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 CDO72724.1 - 1.5e-20 73.4 0.0 8.8e-20 70.9 0.0 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA PF00004.24 CDO72724.1 - 7.5e-13 48.8 0.2 0.0018 18.4 0.0 5.0 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDO72724.1 - 1.4e-12 47.8 0.0 0.021 14.9 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 CDO72724.1 - 7.3e-11 42.1 2.4 0.1 12.4 0.0 5.7 5 1 1 6 6 6 3 AAA domain AAA_17 PF13207.1 CDO72724.1 - 1.4e-08 35.5 0.9 0.1 13.3 0.0 6.1 6 0 0 6 6 4 1 AAA domain AAA_18 PF13238.1 CDO72724.1 - 7.3e-08 32.7 4.0 0.023 14.9 0.0 6.3 6 0 0 6 6 6 1 AAA domain FtsK_SpoIIIE PF01580.13 CDO72724.1 - 5e-07 29.3 3.1 0.54 9.7 0.0 5.5 6 0 0 6 6 4 2 FtsK/SpoIIIE family AAA_16 PF13191.1 CDO72724.1 - 5.7e-07 29.6 9.7 0.2 11.5 0.1 6.7 6 1 0 7 7 6 2 AAA ATPase domain T2SE PF00437.15 CDO72724.1 - 2.1e-06 26.8 0.0 0.041 12.7 0.0 3.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_19 PF13245.1 CDO72724.1 - 5.6e-06 26.0 0.0 0.85 9.4 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 CDO72724.1 - 1.6e-05 24.1 2.2 0.5 9.5 0.0 3.8 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CDO72724.1 - 1.6e-05 24.3 0.0 0.69 9.4 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_14 PF13173.1 CDO72724.1 - 2.7e-05 24.0 0.0 0.55 10.1 0.0 4.1 4 0 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 CDO72724.1 - 0.00023 20.6 0.7 0.36 10.2 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CDO72724.1 - 0.0011 19.1 0.0 4.6 7.4 0.0 4.7 5 0 0 5 5 4 1 RNA helicase BRE1 PF08647.6 CDO72724.1 - 0.0018 18.1 5.5 0.0018 18.1 3.8 3.6 3 0 0 3 3 2 1 BRE1 E3 ubiquitin ligase AAA_25 PF13481.1 CDO72724.1 - 0.0035 16.7 0.0 1.9 7.8 0.0 4.1 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.22 CDO72724.1 - 0.0075 16.5 5.1 9.9 6.4 0.0 4.8 5 0 0 5 5 3 0 ABC transporter AAA_10 PF12846.2 CDO72724.1 - 0.028 13.8 5.0 8.3 5.7 0.2 4.8 4 0 0 4 4 4 0 AAA-like domain MobB PF03205.9 CDO72724.1 - 0.041 13.5 0.1 22 4.7 0.0 3.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 CDO72724.1 - 0.13 12.1 4.5 3.5 7.4 0.0 4.5 6 0 0 6 6 4 0 Type III restriction enzyme, res subunit SMC_N PF02463.14 CDO72724.1 - 0.8 8.8 0.0 18 4.4 0.0 2.9 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain PLRV_ORF5 PF01690.12 CDO72724.1 - 2.8 7.0 3.6 6.1 5.8 2.5 1.5 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LSM PF01423.17 CDO72725.1 - 2.4e-14 52.6 0.8 3.2e-14 52.2 0.5 1.2 1 0 0 1 1 1 1 LSM domain Romo1 PF10247.4 CDO72726.1 - 7.1e-23 80.5 6.0 9.3e-23 80.2 4.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 TPR_11 PF13414.1 CDO72727.1 - 6.6e-05 22.4 2.8 0.0018 17.9 0.2 3.1 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 CDO72727.1 - 0.00037 19.9 0.7 0.09 12.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat 2_5_RNA_ligase2 PF13563.1 CDO72727.1 - 0.079 12.6 1.8 0.095 12.4 0.1 1.9 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily TPR_2 PF07719.12 CDO72727.1 - 0.25 11.3 4.1 2.2 8.4 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4439 PF14530.1 CDO72727.1 - 3.8 7.9 12.1 1.4 9.4 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4439) Ammonium_transp PF00909.16 CDO72728.1 - 2.4e-66 223.8 5.1 5.2e-47 160.1 1.8 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family DUF3512 PF12024.3 CDO72729.1 - 0.1 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) L51_S25_CI-B8 PF05047.11 CDO72730.1 - 3.8e-12 45.7 0.4 6e-12 45.1 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PBP1_TM PF14812.1 CDO72731.1 - 0.26 11.6 1.5 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aldo_ket_red PF00248.16 CDO72733.1 - 4.7e-45 153.5 0.0 6.1e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ala_racemase_N PF01168.15 CDO72733.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain IGPS PF00218.16 CDO72734.1 - 5.3e-92 307.4 0.0 6.1e-92 307.2 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.14 CDO72734.1 - 0.0018 17.8 0.2 0.0034 16.9 0.1 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.13 CDO72734.1 - 0.019 13.8 0.2 0.029 13.2 0.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.16 CDO72734.1 - 0.026 13.8 0.2 0.11 11.7 0.1 1.9 2 1 1 3 3 3 0 Histidine biosynthesis protein F-box-like PF12937.2 CDO72735.1 - 7e-05 22.4 0.2 0.00021 20.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO72735.1 - 0.0026 17.3 0.0 0.007 15.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain G10 PF01125.12 CDO72735.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 G10 protein DLH PF01738.13 CDO72736.1 - 9.7e-16 57.7 0.0 1.1e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CDO72736.1 - 0.00033 20.4 0.0 0.00066 19.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CDO72737.1 - 4.3e-12 45.7 0.0 5.1e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Pkinase PF00069.20 CDO72738.1 - 1.8e-50 171.5 0.0 1.6e-49 168.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain RhoGAP PF00620.22 CDO72738.1 - 7.8e-41 139.2 0.1 1.6e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Pkinase_Tyr PF07714.12 CDO72738.1 - 1.3e-37 129.2 0.0 1.6e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CDO72738.1 - 0.029 13.3 0.0 0.096 11.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like RRM_1 PF00076.17 CDO72739.1 - 1.8e-14 53.0 0.1 2.6e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO72739.1 - 3.4e-09 36.5 0.0 5.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO72739.1 - 1.3e-08 34.5 0.2 2.2e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 CDO72739.1 - 2e-08 33.7 4.2 3.3e-08 33.0 2.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDO72739.1 - 4e-05 23.2 0.0 8.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CDO72739.1 - 0.00055 19.5 0.1 0.00094 18.7 0.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 CDO72739.1 - 0.015 14.7 5.3 0.035 13.5 1.8 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RNA_bind PF08675.6 CDO72739.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain RRM_3 PF08777.6 CDO72739.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif UCR_TM PF02921.9 CDO72740.1 - 5.3e-19 68.2 0.5 1.3e-18 66.9 0.3 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 CDO72740.1 - 1.8e-17 62.6 0.1 3.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF4078 PF13300.1 CDO72740.1 - 0.066 13.3 0.8 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) GDPD PF03009.12 CDO72741.1 - 7.7e-36 123.9 0.0 1.2e-35 123.2 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 CDO72741.1 - 0.00014 21.8 1.1 0.0011 19.0 0.1 2.6 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family CHCH PF06747.8 CDO72742.1 - 5.3e-07 29.4 2.0 8.7e-07 28.7 1.4 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 CDO72742.1 - 0.062 13.3 1.1 0.12 12.4 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NPL4 PF05021.10 CDO72743.1 - 1.1e-95 320.3 0.0 1.4e-95 320.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CDO72743.1 - 1.3e-64 216.2 0.0 2.2e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 CDO72743.1 - 0.00013 22.1 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 DNA_pol_A_exo1 PF01612.15 CDO72744.1 - 2.9e-19 69.2 0.1 3.5e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 3'-5' exonuclease VSP PF03302.8 CDO72745.1 - 0.008 14.8 0.1 0.012 14.2 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein SprB PF13573.1 CDO72745.1 - 0.02 14.4 1.4 0.049 13.2 0.0 2.4 2 0 0 2 2 2 0 SprB repeat Las1 PF04031.8 CDO72746.1 - 1.7e-45 154.4 0.0 6e-45 152.6 0.0 1.9 2 0 0 2 2 2 1 Las1-like p450 PF00067.17 CDO72747.1 - 3e-49 167.7 0.0 8.4e-49 166.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 rve PF00665.21 CDO72748.1 - 2.9e-11 43.5 0.0 6.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CDO72748.1 - 0.032 14.2 0.0 0.086 12.8 0.0 1.7 2 0 0 2 2 2 0 DDE domain ATP_transf PF09830.4 CDO72749.1 - 1.8e-18 66.0 0.0 3.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase SKG6 PF08693.5 CDO72751.1 - 0.00016 20.9 3.0 0.00037 19.7 2.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 CDO72751.1 - 0.09 11.0 0.0 0.13 10.5 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2029 PF09594.5 CDO72751.1 - 0.16 11.4 2.6 0.11 11.9 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) DUF605 PF04652.11 CDO72751.1 - 6.8 5.9 18.3 0.072 12.4 6.0 1.9 2 0 0 2 2 2 0 Vta1 like YcfA PF07927.7 CDO72752.1 - 0.00033 20.5 0.0 0.00095 19.0 0.0 1.8 1 0 0 1 1 1 1 YcfA-like protein RabGAP-TBC PF00566.13 CDO72753.1 - 1.1e-50 172.1 0.0 1.6e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cullin_binding PF03556.10 CDO72753.1 - 5.6 7.1 7.6 0.25 11.4 0.5 2.3 3 0 0 3 3 3 0 Cullin binding Ran_BP1 PF00638.13 CDO72754.1 - 1.6e-12 47.4 0.4 3.2e-12 46.5 0.3 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 CDO72754.1 - 9.4e-12 45.1 0.3 9.4e-12 45.1 0.2 7.3 5 3 1 6 6 6 1 NUP50 (Nucleoporin 50 kDa) TIG PF01833.19 CDO72755.1 - 5.5e-12 45.5 0.5 1.6e-11 44.0 0.3 1.9 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.25 CDO72755.1 - 1.4e-10 40.4 1.3 0.0004 20.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CDO72755.1 - 1.9e-10 40.9 0.0 3.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDO72755.1 - 1.3e-07 31.6 0.7 2.7e-05 24.2 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO72755.1 - 2.8e-07 30.1 0.2 0.0044 17.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CDO72755.1 - 1.5e-06 28.5 0.2 3.5e-05 24.1 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF1639 PF07797.9 CDO72755.1 - 0.081 12.3 1.1 4.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) F-box-like PF12937.2 CDO72756.1 - 0.036 13.7 0.1 0.29 10.8 0.0 2.6 2 0 0 2 2 2 0 F-box-like UDPGT PF00201.13 CDO72757.1 - 4.7e-23 81.5 0.1 6.5e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CDO72757.1 - 0.00046 19.8 0.0 0.00088 18.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CDO72757.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 1 Fe_hyd_lg_C PF02906.9 CDO72759.1 - 1.7e-55 188.2 0.0 3.1e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SNARE PF05739.14 CDO72760.1 - 4.7e-18 64.6 0.6 1.5e-17 63.0 0.4 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 CDO72760.1 - 4.8e-12 45.9 0.4 3.7e-09 36.6 0.0 2.7 2 0 0 2 2 2 2 Syntaxin Syntaxin_2 PF14523.1 CDO72760.1 - 0.066 13.2 3.2 0.58 10.2 0.2 2.8 2 1 0 2 2 2 0 Syntaxin-like protein MCPsignal PF00015.16 CDO72760.1 - 0.1 12.1 9.2 0.21 11.0 0.5 3.0 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 CDO72760.1 - 0.17 12.0 3.2 0.42 10.7 1.0 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MS_channel PF00924.13 CDO72761.1 - 1.3e-23 83.4 0.2 2.2e-23 82.6 0.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CDO72761.1 - 0.0038 16.4 0.7 0.0083 15.3 0.5 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CDO72761.1 - 0.0057 16.7 0.4 0.015 15.3 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CDO72761.1 - 0.014 15.2 0.1 0.067 13.1 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 CDO72761.1 - 0.15 11.4 0.7 0.36 10.2 0.1 1.9 2 0 0 2 2 2 0 EF hand RNA_pol_A_bac PF01000.21 CDO72762.1 - 4.1e-17 62.3 0.0 7.3e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CDO72762.1 - 3.1e-06 26.1 0.0 1.5e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pro-kuma_activ PF09286.6 CDO72763.1 - 9.7e-39 132.6 0.0 1.1e-37 129.2 0.0 2.4 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO72763.1 - 2.1e-07 30.3 0.3 3.9e-07 29.4 0.1 1.4 1 1 0 1 1 1 1 Subtilase family UDPGT PF00201.13 CDO72764.1 - 1.9e-22 79.5 0.0 3.9e-22 78.4 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CDO72764.1 - 0.0039 16.8 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CDO72764.1 - 0.067 12.3 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 1 LETM1 PF07766.8 CDO72765.1 - 2.7e-28 98.7 0.3 2.6e-13 49.6 0.0 2.1 1 1 1 2 2 2 2 LETM1-like protein TPR_11 PF13414.1 CDO72766.1 - 1.3e-49 165.6 41.8 1.2e-09 37.7 0.5 13.3 9 4 2 13 13 13 11 TPR repeat TPR_16 PF13432.1 CDO72766.1 - 2e-38 130.2 88.3 7.1e-08 32.9 1.6 16.5 12 4 7 19 19 19 12 Tetratricopeptide repeat TPR_2 PF07719.12 CDO72766.1 - 4.1e-36 119.9 60.0 1e-05 25.0 0.4 19.3 19 0 0 19 19 19 9 Tetratricopeptide repeat TPR_1 PF00515.23 CDO72766.1 - 4.6e-36 120.9 22.2 1e-05 24.8 0.1 15.1 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_14 PF13428.1 CDO72766.1 - 2.2e-28 96.1 85.1 0.0002 21.6 0.4 20.3 14 6 7 21 21 21 9 Tetratricopeptide repeat TPR_8 PF13181.1 CDO72766.1 - 7.6e-25 84.7 18.5 0.00039 19.9 0.1 14.7 15 1 1 16 16 15 5 Tetratricopeptide repeat TPR_17 PF13431.1 CDO72766.1 - 1.1e-24 84.5 22.5 0.04 14.1 0.0 16.4 18 1 0 18 18 17 5 Tetratricopeptide repeat TPR_12 PF13424.1 CDO72766.1 - 1.4e-22 79.3 53.2 0.00013 21.8 0.9 12.6 8 4 7 15 15 15 11 Tetratricopeptide repeat TPR_19 PF14559.1 CDO72766.1 - 1e-19 70.6 52.8 0.00043 20.5 0.2 14.2 10 4 4 15 15 15 6 Tetratricopeptide repeat TPR_7 PF13176.1 CDO72766.1 - 1e-13 49.9 30.1 0.057 13.2 0.2 13.6 14 0 0 14 14 13 5 Tetratricopeptide repeat Apc3 PF12895.2 CDO72766.1 - 9.4e-12 44.9 19.4 6e-05 23.0 0.0 9.7 7 4 5 12 12 12 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CDO72766.1 - 5.4e-10 39.0 37.7 0.12 12.8 0.2 15.3 18 1 0 18 18 15 3 Tetratricopeptide repeat TPR_9 PF13371.1 CDO72766.1 - 7.1e-09 35.3 2.8 1e-05 25.2 0.1 10.4 10 2 1 12 12 12 3 Tetratricopeptide repeat RPN7 PF10602.4 CDO72766.1 - 0.014 14.8 12.0 1.9 7.8 0.1 6.0 7 2 0 7 7 7 0 26S proteasome subunit RPN7 TOM20_plant PF06552.7 CDO72766.1 - 0.17 11.4 2.0 5.1 6.6 0.0 4.0 5 0 0 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_20 PF14561.1 CDO72766.1 - 7.2 6.7 27.1 0.64 10.1 0.0 8.4 10 4 3 13 13 11 0 Tetratricopeptide repeat Chitin_synth_2 PF03142.10 CDO72767.1 - 8.7e-248 822.9 0.1 1.1e-247 822.6 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CDO72767.1 - 4.3e-17 62.4 6.4 4.3e-17 62.4 4.5 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CDO72767.1 - 2.7e-16 60.0 0.0 9.9e-15 54.9 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CDO72767.1 - 8.2e-06 25.5 0.0 0.00041 20.1 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 CDO72767.1 - 1.1e-05 24.7 0.0 0.00084 18.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CDO72767.1 - 0.01 15.5 0.0 0.091 12.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 DIPSY PF11763.3 CDO72767.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal DSPc PF00782.15 CDO72768.1 - 7e-05 22.4 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CDO72768.1 - 0.00069 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CDO72768.1 - 0.0031 16.8 0.4 0.017 14.4 0.3 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CDO72768.1 - 0.0041 16.5 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 CDO72768.1 - 0.029 14.6 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Type_III_YscX PF09474.5 CDO72770.1 - 0.084 12.9 0.4 0.11 12.4 0.3 1.2 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) HTH_20 PF12840.2 CDO72770.1 - 0.17 11.7 1.2 2 8.2 0.1 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain DOCK-C2 PF14429.1 CDO72772.1 - 9.4e-44 149.2 0.0 2.8e-43 147.7 0.0 1.8 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 CDO72772.1 - 1.8e-40 138.1 0.0 3.2e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 Dedicator of cytokinesis DASH_Spc34 PF08657.5 CDO72773.1 - 1.4e-05 24.8 6.4 0.013 15.2 0.0 2.8 2 1 0 2 2 2 2 DASH complex subunit Spc34 SlyX PF04102.7 CDO72773.1 - 0.039 14.3 4.6 1 9.7 0.6 2.7 2 0 0 2 2 2 0 SlyX Fmp27_WPPW PF10359.4 CDO72773.1 - 0.1 10.9 0.9 0.16 10.3 0.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 CDO72773.1 - 0.16 11.5 3.4 0.31 10.6 2.4 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 CDO72773.1 - 0.55 8.0 1.8 0.81 7.4 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 CDO72773.1 - 1.2 7.5 3.4 2.1 6.6 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 CDO72773.1 - 2.4 7.6 7.0 0.8 9.2 2.3 1.9 2 0 0 2 2 2 0 Septum formation initiator FlxA PF14282.1 CDO72773.1 - 3.4 7.6 8.8 11 5.9 6.1 1.8 1 1 0 1 1 1 0 FlxA-like protein Prefoldin_3 PF13758.1 CDO72773.1 - 5.5 6.8 6.0 0.81 9.5 0.1 2.3 3 0 0 3 3 3 0 Prefoldin subunit HR1 PF02185.11 CDO72773.1 - 6.5 6.5 10.4 51 3.7 0.3 2.3 1 1 1 2 2 2 0 Hr1 repeat DHDPS PF00701.17 CDO72774.1 - 2e-30 105.3 0.0 8e-30 103.4 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family DSPc PF00782.15 CDO72775.1 - 6.9e-31 106.5 0.0 1e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Form_Nir_trans PF01226.12 CDO72776.1 - 1.6e-41 141.8 9.8 1.6e-41 141.8 6.8 1.4 2 0 0 2 2 2 1 Formate/nitrite transporter Abi PF02517.11 CDO72776.1 - 2.4 8.3 5.0 1.4 9.0 2.2 1.6 2 0 0 2 2 2 0 CAAX protease self-immunity MyTH4 PF00784.12 CDO72777.1 - 2.2e-29 101.6 0.0 4.7e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.22 CDO72777.1 - 3.2e-27 94.9 0.0 5.4e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain UDPGT PF00201.13 CDO72778.1 - 2.8e-17 62.4 0.1 3.8e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase G-alpha PF00503.15 CDO72779.1 - 3.8e-113 378.1 0.0 4.9e-113 377.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CDO72779.1 - 4.6e-13 48.7 0.1 2.5e-09 36.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.13 CDO72779.1 - 0.0085 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 CDO72779.1 - 0.009 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CDO72779.1 - 0.084 12.2 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1932 PF09130.6 CDO72781.1 - 1.5e-14 53.4 0.3 6e-14 51.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 CDO72781.1 - 4.6e-08 33.0 0.0 9.3e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CDO72781.1 - 4.5e-06 26.1 0.0 8.3e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 CDO72781.1 - 0.0019 18.5 0.1 0.0049 17.2 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CDO72781.1 - 0.014 14.8 0.1 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 CDO72781.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ComA PF02679.10 CDO72782.1 - 1.3e-64 217.5 0.0 2e-64 216.9 0.0 1.3 1 1 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) PEP_mutase PF13714.1 CDO72782.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Pox_A21 PF05323.7 CDO72782.1 - 0.051 13.9 0.0 0.082 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A21 Protein GST_N PF02798.15 CDO72783.1 - 2.9e-15 56.1 0.0 7.6e-15 54.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO72783.1 - 1.3e-13 50.7 0.0 2.6e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CDO72783.1 - 2.4e-13 49.8 0.1 3.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CDO72783.1 - 2.5e-12 46.8 0.0 4.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO72783.1 - 4.5e-08 32.8 0.0 8.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO72783.1 - 1.8e-05 25.0 0.1 3.4e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CDO72784.1 - 4.8e-16 58.7 0.0 1.2e-15 57.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO72784.1 - 1.7e-13 50.3 0.0 3.6e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CDO72784.1 - 4.4e-12 46.0 0.0 7.6e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CDO72784.1 - 6.2e-09 35.7 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO72784.1 - 1.5e-06 28.0 0.0 3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO72784.1 - 6e-05 23.4 0.0 0.00014 22.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CDO72785.1 - 1.2e-16 60.6 0.0 3e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO72785.1 - 3.5e-14 52.5 0.0 8.2e-14 51.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CDO72785.1 - 1.9e-13 50.2 0.0 2.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CDO72785.1 - 7.3e-13 48.5 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO72785.1 - 4.6e-08 32.8 0.0 8.2e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO72785.1 - 2.2e-06 28.0 0.1 3.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Plant_NMP1 PF06694.6 CDO72785.1 - 0.11 11.3 0.1 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) zf-C2H2_4 PF13894.1 CDO72788.1 - 2.4e-08 33.7 17.6 4.5e-06 26.6 1.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CDO72788.1 - 5e-07 29.6 16.1 2.6e-06 27.4 3.8 3.2 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CDO72788.1 - 6e-07 29.4 18.0 0.00056 20.1 1.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CDO72788.1 - 0.00061 19.5 5.4 0.00061 19.5 3.7 2.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 CDO72788.1 - 0.0098 16.0 4.4 0.16 12.2 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CDO72788.1 - 0.12 12.5 2.9 3.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fungal_trans PF04082.13 CDO72789.1 - 3.8e-19 68.5 2.0 4.2e-19 68.4 0.7 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pro-kuma_activ PF09286.6 CDO72790.1 - 1e-37 129.3 0.1 2e-37 128.3 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO72790.1 - 3.7e-07 29.5 2.4 5.6e-07 28.9 1.7 1.4 1 0 0 1 1 1 1 Subtilase family O-FucT PF10250.4 CDO72791.1 - 1.2e-08 34.4 0.0 1.7e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Cellulase PF00150.13 CDO72792.1 - 2.5e-07 30.1 0.0 4.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.3 CDO72792.1 - 0.0094 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) RAP1 PF07218.6 CDO72792.1 - 0.67 7.9 0.7 0.88 7.5 0.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF563 PF04577.9 CDO72793.1 - 7.1e-21 75.0 0.1 2.5e-19 69.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF563) MIP PF00230.15 CDO72794.1 - 7.2e-25 87.7 7.8 1e-24 87.2 5.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.15 CDO72795.1 - 5.8e-26 91.3 2.8 7.6e-26 90.9 1.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ferrochelatase PF00762.14 CDO72797.1 - 7.8e-100 333.9 0.0 8.8e-100 333.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 CDO72797.1 - 0.0025 17.8 0.0 21 5.2 0.0 3.2 3 0 0 3 3 3 3 CbiX DUF2419 PF10343.4 CDO72798.1 - 1.5e-06 27.7 0.0 0.00075 18.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) NAD_kinase PF01513.16 CDO72799.1 - 1.2e-67 227.7 0.0 2.5e-67 226.6 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase Axin_b-cat_bind PF08833.5 CDO72801.1 - 0.072 12.8 0.3 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 Axin beta-catenin binding domain HMG_box PF00505.14 CDO72802.1 - 4.1e-13 49.3 3.4 4.1e-13 49.3 2.3 2.2 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO72802.1 - 2.9e-05 24.3 1.3 2.9e-05 24.3 0.9 2.3 1 1 1 2 2 2 1 HMG-box domain HMG_box PF00505.14 CDO72803.1 - 6.1e-11 42.4 0.7 9.8e-11 41.7 0.5 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO72803.1 - 0.002 18.4 1.2 0.0035 17.6 0.8 1.5 1 0 0 1 1 1 1 HMG-box domain DUF829 PF05705.9 CDO72804.1 - 2.3e-44 151.8 0.0 2.6e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Gsf2 PF11055.3 CDO72804.1 - 0.07 11.6 0.0 0.094 11.2 0.0 1.2 1 0 0 1 1 1 0 Glucose signalling factor 2 Abhydrolase_6 PF12697.2 CDO72804.1 - 0.093 12.5 0.1 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pro_Al_protease PF02983.9 CDO72805.1 - 0.48 10.4 2.6 1.7 8.6 1.8 1.9 1 0 0 1 1 1 0 Alpha-lytic protease prodomain MCM PF00493.18 CDO72806.1 - 9.6e-139 461.7 0.2 1.4e-138 461.2 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 CDO72806.1 - 7.2e-31 107.2 35.6 7.2e-31 107.2 24.6 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CDO72806.1 - 4.1e-16 59.5 0.0 1.2e-15 58.0 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CDO72806.1 - 1.1e-07 31.2 0.0 3.5e-06 26.3 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CDO72806.1 - 3.6e-06 26.7 0.1 1.1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CDO72806.1 - 0.00044 19.8 0.1 0.019 14.5 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CDO72806.1 - 0.0014 18.1 0.1 0.011 15.1 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain L_lactis_RepB_C PF06430.7 CDO72806.1 - 0.023 14.7 0.5 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Lactococcus lactis RepB C-terminus AAA PF00004.24 CDO72806.1 - 0.07 13.3 0.1 1.1 9.4 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HMG_box PF00505.14 CDO72807.1 - 1.6e-14 53.9 0.3 1.6e-14 53.9 0.2 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO72807.1 - 3.7e-05 23.9 0.3 3.7e-05 23.9 0.2 2.0 2 0 0 2 2 2 1 HMG-box domain ABC_tran PF00005.22 CDO72808.1 - 1.3e-33 116.1 0.0 2.6e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CDO72808.1 - 7.9e-30 104.2 8.9 1.4e-29 103.4 6.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CDO72808.1 - 1.2e-06 28.7 0.1 0.0044 17.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CDO72808.1 - 4.5e-05 23.5 0.1 0.00018 21.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 CDO72808.1 - 4.5e-05 22.7 0.1 0.00074 18.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CDO72808.1 - 0.00083 18.8 0.1 0.002 17.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CDO72808.1 - 0.0066 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CDO72808.1 - 0.0079 16.3 0.1 0.04 14.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDO72808.1 - 0.059 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF4014 PF13198.1 CDO72808.1 - 0.15 12.4 1.1 1.6 9.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) AAA_17 PF13207.1 CDO72808.1 - 0.16 12.8 0.0 0.4 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.17 CDO72809.1 - 1.5e-10 40.5 0.0 2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO72809.1 - 3e-09 36.7 0.0 3.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO72809.1 - 4.1e-08 32.9 0.0 5.5e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_3 PF13456.1 CDO72810.1 - 0.0061 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Phage_integrase PF00589.17 CDO72810.1 - 0.19 11.3 0.1 0.58 9.8 0.0 1.8 2 0 0 2 2 2 0 Phage integrase family Gelsolin PF00626.17 CDO72812.1 - 2.5e-15 55.9 0.0 9.6e-09 34.8 0.0 2.5 2 0 0 2 2 2 2 Gelsolin repeat RVT_2 PF07727.9 CDO72813.1 - 2.9e-08 32.9 0.0 4.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OmpH PF03938.9 CDO72814.1 - 0.2 11.6 8.7 8.2 6.3 5.1 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TSA PF03249.8 CDO72814.1 - 0.37 9.2 2.4 0.57 8.6 1.6 1.3 1 0 0 1 1 1 0 Type specific antigen UBN_AB PF14075.1 CDO72814.1 - 0.7 9.5 0.0 0.7 9.5 0.0 2.1 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Spore_III_AB PF09548.5 CDO72814.1 - 0.97 9.1 3.8 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF4611 PF15387.1 CDO72814.1 - 1.3 9.2 11.7 5.3 7.2 4.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3886 PF13025.1 CDO72814.1 - 2.9 7.9 16.6 7.6 6.5 11.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Peptidase_S49_N PF08496.5 CDO72814.1 - 5.6 6.7 7.9 13 5.5 5.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ATP-synt_E PF05680.7 CDO72814.1 - 7.3 6.6 9.1 1.6 8.7 3.4 2.0 2 0 0 2 2 2 0 ATP synthase E chain RVT_1 PF00078.22 CDO72815.1 - 8.2e-20 71.0 0.0 1.4e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO72815.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 CDO72816.1 - 1.7e-14 53.0 8.0 0.0002 21.1 0.0 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat SRA1 PF07304.6 CDO72816.1 - 6.9e-10 38.8 0.0 3.2e-09 36.7 0.0 2.2 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 CDO72816.1 - 0.023 14.5 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Prp18 domain Lipase_3 PF01764.20 CDO72817.1 - 1.9e-08 34.0 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CDO72817.1 - 0.036 13.9 0.5 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO72817.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO72817.1 - 0.08 12.6 0.4 0.17 11.6 0.1 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Tad PF13400.1 CDO72818.1 - 0.057 13.4 8.3 1.3 9.0 0.3 3.4 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF485 PF04341.7 CDO72818.1 - 5.7 6.7 7.4 3.1 7.5 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Aldo_ket_red PF00248.16 CDO72820.1 - 7e-45 153.0 0.0 1e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Transp_cyt_pur PF02133.10 CDO72821.1 - 1.3e-63 215.1 36.6 5.9e-46 156.9 11.3 3.0 1 1 2 3 3 3 3 Permease for cytosine/purines, uracil, thiamine, allantoin ICMT PF04140.9 CDO72822.1 - 6.8e-15 55.0 0.9 6.8e-15 55.0 0.6 2.7 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO72822.1 - 1.8e-11 44.0 0.2 2.8e-10 40.2 0.3 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO72822.1 - 1.1e-08 34.0 0.2 1.5e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CDO72822.1 - 0.026 13.8 0.4 0.039 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) EF-hand_9 PF14658.1 CDO72822.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain GMC_oxred_C PF05199.8 CDO72823.1 - 3.8e-38 131.0 0.1 6e-38 130.3 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CDO72823.1 - 8.2e-34 117.1 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GST_N_3 PF13417.1 CDO72824.1 - 2.3e-14 53.3 0.0 4.3e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO72824.1 - 5.6e-10 39.0 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO72824.1 - 2e-05 24.6 0.0 6.7e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CDO72824.1 - 9.9e-05 22.7 0.0 0.00017 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO72824.1 - 0.0022 17.8 0.2 0.005 16.7 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sec63 PF02889.11 CDO72825.1 - 5e-197 653.4 0.0 3.9e-105 351.5 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CDO72825.1 - 1.8e-50 170.7 0.1 2.1e-28 98.9 0.1 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 CDO72825.1 - 4.4e-16 59.2 0.1 9.4e-11 41.8 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CDO72825.1 - 1.3e-12 47.4 0.0 7.2e-09 35.3 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 CDO72825.1 - 1.9e-06 28.0 0.1 0.045 13.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 CDO72825.1 - 6e-05 22.3 0.0 0.0021 17.2 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 CDO72825.1 - 0.011 14.6 0.0 0.19 10.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF4246 PF14033.1 CDO72826.1 - 1.8e-117 393.0 0.0 1.1e-116 390.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) 3HBOH PF10605.4 CDO72826.1 - 0.023 12.7 0.0 0.033 12.2 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) UDG PF03167.14 CDO72827.1 - 2.1e-17 63.0 0.0 5.5e-17 61.6 0.0 1.7 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily GST_N_3 PF13417.1 CDO72828.1 - 4.1e-06 26.9 0.0 1.6e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO72828.1 - 0.0068 16.3 0.1 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CDO72828.1 - 0.026 15.0 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AMP-binding PF00501.23 CDO72829.1 - 8e-40 136.4 0.0 1e-38 132.8 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 CDO72829.1 - 2.9e-11 43.4 0.3 6.2e-11 42.3 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 CDO72829.1 - 7.9e-11 40.9 2.8 0.00046 19.5 0.1 6.3 7 0 0 7 7 7 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CDO72829.1 - 4.7 6.8 8.5 3.7 7.1 0.3 4.3 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase Mis12 PF05859.7 CDO72830.1 - 4.1e-25 88.2 0.0 5.8e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Mis12 protein Syntaxin-6_N PF09177.6 CDO72830.1 - 0.12 12.7 1.3 0.2 12.0 0.1 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal PilM_2 PF11104.3 CDO72830.1 - 0.16 10.8 0.0 0.75 8.6 0.0 1.8 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Cupin_2 PF07883.6 CDO72831.1 - 9.8e-08 31.3 0.1 0.00025 20.4 0.0 2.5 2 0 0 2 2 2 2 Cupin domain CBFD_NFYB_HMF PF00808.18 CDO72832.1 - 1.2e-19 70.1 0.8 1.7e-19 69.6 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CDO72832.1 - 7.8e-05 22.7 0.1 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 CDO72832.1 - 0.0047 16.7 0.0 0.0082 15.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Peptidase_M36 PF02128.10 CDO72836.1 - 4.6e-117 391.0 8.9 5.9e-117 390.6 6.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) PepSY PF03413.14 CDO72836.1 - 1.4e-06 28.8 1.2 3.1e-06 27.7 0.5 2.0 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain FTP PF07504.8 CDO72836.1 - 7.9e-06 25.2 0.2 1.8e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 CDO72836.1 - 0.00029 20.6 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain DDE_3 PF13358.1 CDO72837.1 - 1.7e-15 57.0 0.4 2.7e-15 56.3 0.3 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO72837.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain EF-hand_8 PF13833.1 CDO72837.1 - 0.015 14.8 0.8 0.031 13.8 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair Phage_Gp15 PF06854.6 CDO72837.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Gp15 protein Methyltransf_16 PF10294.4 CDO72838.1 - 1.6e-07 30.9 0.0 0.012 15.0 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase RhoGEF PF00621.15 CDO72839.1 - 8.5e-21 74.6 0.1 7e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain Asn_synthase PF00733.16 CDO72840.1 - 6.7e-72 242.0 0.0 1.1e-71 241.4 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CDO72840.1 - 1.1e-35 122.0 0.0 1.8e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CDO72840.1 - 3.4e-29 101.4 0.0 8.5e-29 100.1 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CDO72840.1 - 0.00021 20.1 0.0 0.00075 18.3 0.0 1.8 1 1 1 2 2 2 1 Glutamine amidotransferases class-II DUF3700 PF12481.3 CDO72840.1 - 0.00024 20.3 0.0 0.00042 19.5 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 CDO72840.1 - 0.02 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD synthase QueC PF06508.8 CDO72840.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Aldo_ket_red PF00248.16 CDO72841.1 - 1.5e-54 184.7 0.0 1.9e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 CDO72842.1 - 1.9e-57 194.2 0.0 2.1e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Syntaxin PF00804.20 CDO72843.1 - 9e-17 61.1 0.5 9e-17 61.1 0.3 2.8 3 0 0 3 3 3 2 Syntaxin SNARE PF05739.14 CDO72843.1 - 1.2e-12 47.2 5.2 1.2e-12 47.2 3.6 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 CDO72843.1 - 0.00049 20.0 5.1 0.00049 20.0 3.5 2.7 3 0 0 3 3 2 1 Syntaxin-like protein FUSC PF04632.7 CDO72843.1 - 0.0031 16.0 2.9 0.0031 16.0 2.0 2.9 2 1 1 4 4 4 1 Fusaric acid resistance protein family ACC_epsilon PF13822.1 CDO72843.1 - 0.015 15.6 0.1 0.015 15.6 0.1 2.6 3 0 0 3 3 2 0 Acyl-CoA carboxylase epsilon subunit Synaptobrevin PF00957.16 CDO72843.1 - 0.037 13.6 2.2 0.1 12.2 0.1 2.6 2 1 0 2 2 2 0 Synaptobrevin NDK PF00334.14 CDO72843.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Nucleoside diphosphate kinase SF3a60_bindingd PF12108.3 CDO72843.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain VitD-bind_III PF09164.5 CDO72843.1 - 0.17 11.5 0.1 0.65 9.6 0.0 2.0 2 0 0 2 2 2 0 Vitamin D binding protein, domain III MCPsignal PF00015.16 CDO72843.1 - 0.25 10.8 12.1 0.025 14.1 2.0 2.6 3 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3708 PF12501.3 CDO72843.1 - 0.26 11.1 6.0 0.53 10.1 0.4 2.7 2 1 1 3 3 3 0 Phosphate ATP-binding cassette transporter FBP PF07299.6 CDO72843.1 - 0.53 9.5 2.5 1.6 8.0 0.3 2.1 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) MscS_TM PF12794.2 CDO72843.1 - 1.1 7.7 6.2 3.6 6.0 0.0 2.5 2 1 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF1215 PF06744.7 CDO72843.1 - 2.1 7.9 9.0 1 8.9 1.7 2.8 2 1 0 2 2 1 0 Protein of unknown function (DUF1215) ISG65-75 PF11727.3 CDO72843.1 - 2.4 7.1 7.0 1.1 8.2 0.7 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein Aminotran_5 PF00266.14 CDO72844.1 - 2.6e-12 46.1 0.0 1.1e-11 44.0 0.0 1.9 2 1 0 2 2 2 1 Aminotransferase class-V Abhydrolase_5 PF12695.2 CDO72846.1 - 7.5e-08 32.2 0.0 1.6e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CDO72846.1 - 0.00021 20.9 2.7 0.0003 20.4 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF1180 PF06679.7 CDO72847.1 - 3.1 7.6 6.4 3.6 7.4 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Hexapep PF00132.19 CDO72848.1 - 1.5e-16 59.0 10.2 1.8e-06 27.1 1.7 4.6 2 1 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CDO72848.1 - 2.9e-07 29.9 12.3 0.0022 17.5 0.4 4.3 1 1 3 4 4 4 4 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 CDO72848.1 - 6.8e-07 28.8 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CDO72848.1 - 0.0001 22.4 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 CDO72848.1 - 0.0032 16.1 0.3 0.0079 14.8 0.2 1.5 1 1 0 1 1 1 1 L-fucokinase SUR7 PF06687.7 CDO72850.1 - 1e-18 67.7 10.0 1.3e-18 67.3 6.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 CDO72850.1 - 0.0079 16.1 1.1 0.0079 16.1 0.8 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Peptidase_C33 PF05412.7 CDO72850.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase Wzy_C PF04932.10 CDO72850.1 - 1.3 8.8 4.5 7.1 6.4 1.1 2.2 2 0 0 2 2 2 0 O-Antigen ligase Nol1_Nop2_Fmu PF01189.12 CDO72851.1 - 2.9e-102 341.8 0.0 4.1e-102 341.3 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family PCMT PF01135.14 CDO72851.1 - 0.0026 17.3 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 CDO72851.1 - 0.0032 17.0 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 CDO72851.1 - 0.0053 16.3 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CDO72851.1 - 0.014 15.3 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF938 PF06080.7 CDO72851.1 - 0.034 13.6 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FUN14 PF04930.10 CDO72852.1 - 2.3e-18 66.3 0.3 3.6e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 FUN14 family Adeno_E3_14_5 PF04834.7 CDO72852.1 - 0.071 13.5 0.5 0.14 12.6 0.4 1.5 1 0 0 1 1 1 0 Early E3 14.5 kDa protein Mito_fiss_reg PF05308.6 CDO72852.1 - 3.1 7.0 8.4 4.7 6.5 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator SM-ATX PF14438.1 CDO72855.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF4149 PF13664.1 CDO72855.1 - 0.17 11.9 5.8 0.048 13.7 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) APC_crr PF05923.7 CDO72856.1 - 8.9 6.0 6.5 3.7 7.3 1.2 2.6 2 0 0 2 2 2 0 APC cysteine-rich region Transposase_21 PF02992.9 CDO72857.1 - 1e-08 34.5 0.0 1.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO72857.1 - 0.006 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Antimicrobial_1 PF08018.6 CDO72860.1 - 0.13 12.1 0.8 0.27 11.1 0.5 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide ALG3 PF05208.8 CDO72863.1 - 3.3e-99 332.6 18.2 4.5e-73 246.5 4.2 2.0 1 1 1 2 2 2 2 ALG3 protein Peptidase_M13_N PF05649.8 CDO72864.1 - 2.6e-90 303.2 0.6 3.8e-90 302.7 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.16 CDO72864.1 - 3e-56 189.8 0.0 5.1e-56 189.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 SSP160 PF06933.6 CDO72864.1 - 0.9 7.4 11.6 1.4 6.8 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 NAGLU PF05089.7 CDO72865.1 - 2.5e-127 424.2 1.9 3.4e-127 423.8 1.3 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 CDO72865.1 - 4.3e-63 213.1 3.2 5.8e-63 212.7 2.2 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 CDO72865.1 - 1e-12 47.5 0.0 1.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Scramblase PF03803.10 CDO72866.1 - 8.7e-57 191.7 0.0 2.9e-56 190.0 0.0 1.7 1 1 0 1 1 1 1 Scramblase zf-Mss51 PF13824.1 CDO72867.1 - 2.2e-23 81.8 11.9 4.2e-23 80.9 8.3 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.1 CDO72867.1 - 0.011 16.0 5.7 0.023 14.9 3.9 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar Terminase_GpA PF05876.7 CDO72867.1 - 2.7 6.2 5.8 3.9 5.6 4.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) 2OG-FeII_Oxy_2 PF13532.1 CDO72868.1 - 2.7e-14 53.4 0.0 9.3e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HTH_8 PF02954.14 CDO72868.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family IGPD PF00475.13 CDO72869.1 - 1.8e-40 138.1 0.1 4.2e-40 136.9 0.0 1.5 1 1 1 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DUF4149 PF13664.1 CDO72869.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) CDC45 PF02724.9 CDO72870.1 - 5.3e-186 619.3 0.0 6.4e-186 619.0 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein CKAP2_C PF15297.1 CDO72870.1 - 0.019 13.8 1.0 0.033 13.0 0.7 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus CENP-B_dimeris PF09026.5 CDO72870.1 - 3.3 7.9 14.5 9.9 6.4 10.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 CDO72870.1 - 3.4 6.8 8.2 7 5.8 5.7 1.4 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 CDO72870.1 - 4.5 5.0 12.1 6.7 4.4 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 CDO72870.1 - 5.1 6.8 12.7 8.6 6.1 8.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M24 PF00557.19 CDO72871.1 - 9.5e-44 149.4 0.1 1.2e-43 149.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CDO72871.1 - 0.0014 19.1 0.0 0.0022 18.5 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DEAD PF00270.24 CDO72872.1 - 9.7e-49 165.1 0.0 1.7e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO72872.1 - 1.2e-26 92.3 0.0 2.6e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO72872.1 - 1.4e-05 24.9 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.27 CDO72873.1 - 3.6e-07 29.8 5.7 0.064 13.1 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat TRAPPC10 PF12584.3 CDO72874.1 - 1.2e-29 102.7 0.0 3.4e-29 101.2 0.0 1.9 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun PF07919.7 CDO72874.1 - 0.0046 15.3 0.0 0.63 8.2 0.0 2.3 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi MF_alpha_N PF05436.6 CDO72874.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Lyase_1 PF00206.15 CDO72875.1 - 8.2e-102 340.5 0.0 1.2e-101 339.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 CDO72875.1 - 6.6e-28 96.5 0.2 1.4e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Syntaxin PF00804.20 CDO72876.1 - 3.2e-15 56.1 11.2 2.3e-14 53.4 2.0 2.6 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 CDO72876.1 - 3.6e-14 52.2 3.5 3.6e-14 52.2 2.4 2.2 2 1 0 2 2 2 1 SNARE domain Use1 PF09753.4 CDO72876.1 - 0.00036 20.0 4.2 0.00061 19.3 2.9 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 MCPsignal PF00015.16 CDO72876.1 - 0.0011 18.5 1.5 0.0011 18.5 1.0 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.6 CDO72876.1 - 0.0025 16.5 3.0 0.0025 16.5 2.1 2.3 1 1 0 2 2 2 1 Spc7 kinetochore protein Syntaxin_2 PF14523.1 CDO72876.1 - 0.0032 17.4 10.3 0.0032 17.4 7.1 2.7 2 1 0 2 2 2 1 Syntaxin-like protein TRP PF06011.7 CDO72876.1 - 0.0086 14.6 0.1 0.014 14.0 0.1 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel VitD-bind_III PF09164.5 CDO72876.1 - 0.019 14.5 0.6 0.063 12.9 0.1 2.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Spectrin PF00435.16 CDO72876.1 - 0.022 15.0 9.0 0.1 12.8 0.0 3.2 3 1 0 3 3 3 0 Spectrin repeat V-SNARE PF05008.10 CDO72876.1 - 0.044 13.9 15.3 0.046 13.8 0.9 3.9 2 2 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Laminin_II PF06009.7 CDO72876.1 - 0.046 13.4 14.0 0.071 12.8 1.6 2.6 3 0 0 3 3 2 0 Laminin Domain II TPR_2 PF07719.12 CDO72876.1 - 0.078 12.9 1.4 0.15 12.0 0.1 2.2 3 0 0 3 3 1 0 Tetratricopeptide repeat COG2 PF06148.6 CDO72876.1 - 0.14 12.0 6.7 0.37 10.6 0.2 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 EMP24_GP25L PF01105.19 CDO72876.1 - 0.31 10.7 8.0 0.44 10.2 1.0 2.9 2 2 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2077 PF09850.4 CDO72876.1 - 0.31 10.4 2.9 0.45 9.8 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) PBP1_TM PF14812.1 CDO72876.1 - 0.44 10.8 0.0 0.44 10.8 0.0 2.6 3 0 0 3 3 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF848 PF05852.6 CDO72876.1 - 0.52 10.1 10.3 0.56 10.0 1.0 2.8 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Tweety PF04906.8 CDO72876.1 - 0.57 8.5 9.3 0.018 13.5 0.8 2.2 2 1 0 2 2 2 0 Tweety ABC2_membrane_3 PF12698.2 CDO72876.1 - 0.6 9.0 6.6 0.036 13.1 0.2 1.9 1 1 0 2 2 2 0 ABC-2 family transporter protein DUF1664 PF07889.7 CDO72876.1 - 0.61 9.8 6.0 2.5 7.8 0.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.6 CDO72876.1 - 0.82 8.9 6.8 1.5 8.0 1.1 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein BLOC1_2 PF10046.4 CDO72876.1 - 1.1 9.4 11.5 0.3 11.2 1.0 3.5 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 CDO72876.1 - 1.4 8.7 15.8 0.38 10.5 1.1 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Herpes_UL45 PF05473.7 CDO72876.1 - 2.1 7.7 5.1 0.78 9.1 0.9 2.1 2 1 0 2 2 2 0 UL45 protein TBPIP PF07106.8 CDO72876.1 - 2.2 7.8 16.1 0.86 9.1 1.2 3.1 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MMPL PF03176.10 CDO72876.1 - 2.2 6.9 5.4 0.44 9.2 0.7 2.0 2 0 0 2 2 2 0 MMPL family AAA_13 PF13166.1 CDO72876.1 - 3.2 6.0 15.8 8.8 4.6 8.7 2.3 1 1 1 2 2 2 0 AAA domain NPV_P10 PF05531.7 CDO72876.1 - 4.1 7.7 14.3 9.9 6.4 1.6 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.4 CDO72876.1 - 4.9 7.4 10.3 4.8 7.4 0.5 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) MtrG PF04210.8 CDO72876.1 - 5.1 6.8 6.0 7 6.3 0.1 2.8 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Wbp11 PF09429.5 CDO72876.1 - 6 6.9 14.8 0.76 9.8 0.9 3.5 3 0 0 3 3 3 0 WW domain binding protein 11 DUF3510 PF12022.3 CDO72876.1 - 7.3 6.7 10.5 0.31 11.1 0.7 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF3510) Phasin PF05597.6 CDO72876.1 - 7.8 6.2 11.0 1.1 9.0 0.2 3.2 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Nup54 PF13874.1 CDO72876.1 - 9.5 5.8 13.7 0.35 10.5 0.6 3.2 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 zf-AN1 PF01428.11 CDO72877.1 - 6.6e-10 38.7 10.9 1.1e-09 38.0 7.5 1.4 1 1 0 1 1 1 1 AN1-like Zinc finger zf-RING_4 PF14570.1 CDO72877.1 - 0.28 10.8 8.1 0.058 12.9 3.0 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.16 CDO72877.1 - 0.43 10.4 10.1 0.66 9.8 6.6 1.7 1 1 0 1 1 1 0 IBR domain LELP1 PF15042.1 CDO72877.1 - 1.3 9.2 5.4 1.6 8.9 3.8 1.2 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Aminotran_1_2 PF00155.16 CDO72878.1 - 2.8e-82 276.5 0.0 3.3e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HEAT PF02985.17 CDO72879.1 - 1.8e-21 74.2 21.6 0.00014 21.6 0.1 8.9 8 0 0 8 8 8 7 HEAT repeat HEAT_2 PF13646.1 CDO72879.1 - 5.4e-12 45.8 17.2 2.6e-05 24.4 0.0 6.2 6 1 1 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 CDO72879.1 - 2e-06 28.0 26.0 0.0094 16.4 3.1 5.9 6 1 1 7 7 7 4 HEAT-like repeat Cohesin_HEAT PF12765.2 CDO72879.1 - 0.0061 16.4 3.0 0.14 12.1 0.3 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Ist1 PF03398.9 CDO72881.1 - 8.6e-30 103.3 0.1 1.4e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.13 CDO72881.1 - 8.2e-10 38.5 0.3 8.4e-09 35.2 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF1697 PF08002.6 CDO72881.1 - 0.00077 19.5 0.1 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) Cellulase PF00150.13 CDO72882.1 - 7.5e-13 48.3 0.0 1.6e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GTP_EFTU PF00009.22 CDO72883.1 - 1.3e-41 142.1 0.9 7.7e-41 139.5 0.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CDO72883.1 - 2.1e-29 101.5 1.7 5.3e-29 100.2 1.2 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 CDO72883.1 - 5.3e-07 29.5 0.2 3.1e-06 27.1 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CDO72883.1 - 4e-05 23.1 0.8 0.029 13.8 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 CDO72883.1 - 0.00011 21.1 2.8 0.00036 19.4 0.3 2.3 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 CDO72883.1 - 0.0024 18.3 0.0 0.0051 17.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO72883.1 - 0.0027 16.9 0.0 0.008 15.4 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CDO72883.1 - 0.014 14.6 0.0 0.034 13.3 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CHORD PF04968.7 CDO72884.1 - 1.1e-45 153.7 22.0 4.7e-26 90.8 3.3 3.4 2 1 1 3 3 3 3 CHORD CS PF04969.11 CDO72884.1 - 8.2e-15 55.1 0.0 1.9e-14 53.9 0.0 1.6 2 0 0 2 2 2 1 CS domain Rieske PF00355.21 CDO72884.1 - 0.21 11.2 7.8 0.59 9.7 0.8 2.6 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain Mito_carr PF00153.22 CDO72885.1 - 2.1e-05 24.1 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Helicase_C PF00271.26 CDO72886.1 - 2e-13 49.9 0.0 4e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO72886.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase WD40 PF00400.27 CDO72889.1 - 3e-45 150.5 8.9 1.9e-13 49.6 0.1 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CDO72889.1 - 5.6e-08 31.9 0.2 0.0014 17.4 0.0 4.2 2 1 1 3 3 3 2 Nup133 N terminal like Hira PF07569.6 CDO72889.1 - 0.00026 20.2 0.1 0.27 10.3 0.0 2.4 2 0 0 2 2 2 2 TUP1-like enhancer of split Nup160 PF11715.3 CDO72889.1 - 0.0011 17.2 4.1 3.3 5.7 0.0 4.2 3 1 0 4 4 4 3 Nucleoporin Nup120/160 Glu_synthase PF01645.12 CDO72890.1 - 9.7e-160 531.4 0.0 1.5e-159 530.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CDO72890.1 - 2.5e-135 450.8 0.0 3.5e-135 450.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CDO72890.1 - 1.1e-118 395.7 0.0 1.7e-118 395.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 CDO72890.1 - 5.9e-69 231.1 3.4 5.9e-69 231.1 2.4 1.7 2 0 0 2 2 2 1 GXGXG motif Fer4_20 PF14691.1 CDO72890.1 - 4.2e-23 81.0 0.1 9.7e-23 79.9 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CDO72890.1 - 3.8e-18 66.1 0.0 1.6e-17 64.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDO72890.1 - 2.1e-10 41.0 0.3 0.0001 22.4 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO72890.1 - 1.1e-07 31.7 0.0 4.5e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CDO72890.1 - 1.2e-07 32.0 0.0 0.0021 18.4 0.0 3.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO72890.1 - 3.3e-05 22.5 1.1 9.6e-05 21.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 CDO72890.1 - 0.00039 20.0 0.1 0.01 15.4 0.0 2.7 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 CDO72890.1 - 0.00064 18.6 1.3 0.0052 15.6 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 CDO72890.1 - 0.00095 19.3 0.4 0.66 10.2 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 CDO72890.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 CDO72890.1 - 0.0019 17.1 0.0 0.0019 17.1 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 CDO72890.1 - 0.013 15.5 0.1 14 5.7 0.1 3.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 CDO72890.1 - 0.015 14.4 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 CDO72890.1 - 0.015 14.4 0.6 0.05 12.6 0.0 2.1 2 0 0 2 2 2 0 Thi4 family FMN_dh PF01070.13 CDO72890.1 - 0.023 13.5 1.0 0.25 10.1 0.7 2.4 2 0 0 2 2 2 0 FMN-dependent dehydrogenase GATase_6 PF13522.1 CDO72890.1 - 0.028 14.3 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_Gly3P_dh_N PF01210.18 CDO72890.1 - 0.034 13.8 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 CDO72890.1 - 0.036 13.9 0.1 0.094 12.5 0.1 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_oxidored PF12831.2 CDO72890.1 - 0.04 12.9 0.0 0.04 12.9 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CDO72890.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 CDO72890.1 - 0.075 11.8 1.4 0.49 9.1 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 CDO72890.1 - 0.11 12.4 0.5 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain DJ-1_PfpI PF01965.19 CDO72890.1 - 0.15 11.4 0.1 1.2 8.6 0.0 2.2 1 1 1 2 2 2 0 DJ-1/PfpI family UDPG_MGDP_dh_N PF03721.9 CDO72890.1 - 0.16 11.3 0.0 0.39 10.0 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 CDO72890.1 - 0.18 10.9 0.3 1 8.4 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.14 CDO72890.1 - 0.37 8.9 0.1 3.8 5.6 0.0 2.5 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Acetyltransf_13 PF13880.1 CDO72891.1 - 3.9e-12 45.7 0.0 7.5e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 CDO72891.1 - 8.5e-08 31.6 0.1 1.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 CDO72891.1 - 0.0018 18.2 0.0 0.0059 16.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDO72891.1 - 0.18 12.0 0.0 0.63 10.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DEAD PF00270.24 CDO72892.1 - 2.1e-29 102.2 0.0 1.1e-13 51.0 0.0 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase DUF4217 PF13959.1 CDO72892.1 - 2.6e-23 81.3 0.1 6.8e-23 79.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CDO72892.1 - 7.9e-20 70.5 0.0 2.7e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4137 PF13593.1 CDO72892.1 - 0.082 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) DUF4519 PF15012.1 CDO72892.1 - 7.4 6.5 11.3 38 4.3 7.8 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) SOG2 PF10428.4 CDO72893.1 - 4.3e-52 177.2 0.1 4.3e-52 177.2 0.1 2.0 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 CDO72893.1 - 3.6e-11 42.4 1.4 0.00012 21.6 0.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO72893.1 - 4.9e-10 39.0 6.6 1.8e-06 27.5 0.3 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CDO72893.1 - 1.1e-05 24.7 2.3 0.56 10.4 0.0 4.1 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 CDO72893.1 - 0.0003 20.4 1.4 5.9 7.5 0.0 4.0 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 CDO72893.1 - 0.42 10.8 1.6 5.1 7.4 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeat FYVE PF01363.16 CDO72894.1 - 3.1e-17 62.2 1.2 5.3e-17 61.4 0.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.3 CDO72894.1 - 6.6e-06 25.5 0.7 1.6e-05 24.3 0.5 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.8 CDO72894.1 - 0.0056 16.4 4.9 0.0056 16.4 3.4 1.9 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type FYVE_2 PF02318.11 CDO72894.1 - 0.067 13.0 2.0 0.076 12.9 0.4 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger DUF4206 PF13901.1 CDO72894.1 - 0.19 11.2 3.7 0.13 11.7 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) Cofilin_ADF PF00241.15 CDO72895.1 - 7e-20 71.1 0.0 9.8e-10 38.3 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein CoA_trans PF01144.18 CDO72896.1 - 2.4e-105 350.4 0.8 2.7e-62 209.7 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CDO72896.1 - 0.002 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 CDO72896.1 - 0.0025 17.5 0.3 0.033 13.9 0.0 2.7 3 1 0 3 3 3 1 Acetyl-CoA hydrolase/transferase N-terminal domain CoA_trans PF01144.18 CDO72897.1 - 1.2e-94 315.5 4.0 6e-53 179.2 0.5 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CDO72897.1 - 0.037 13.6 0.1 0.074 12.7 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain SMI1_KNR4 PF09346.5 CDO72898.1 - 1.7e-17 63.6 0.0 2.7e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) HSA PF07529.8 CDO72899.1 - 4.2e-18 64.9 1.1 4.2e-18 64.9 0.7 2.6 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 CDO72899.1 - 6.3e-11 42.2 0.5 1.5e-10 40.9 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CDO72899.1 - 5.5e-07 29.5 0.4 1.5e-06 28.1 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain IATP PF04568.7 CDO72900.1 - 0.42 10.6 0.2 0.42 10.6 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Cellulase PF00150.13 CDO72901.1 - 8.2e-13 48.1 0.0 1.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF515 PF04415.7 CDO72901.1 - 0.0019 16.5 0.0 0.0028 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF515) DUF3357 PF11837.3 CDO72901.1 - 0.084 12.7 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Pectate_lyase_3 PF12708.2 CDO72902.1 - 1.7e-77 260.5 23.8 2e-60 204.6 5.9 2.9 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 CDO72902.1 - 1e-06 28.1 0.8 0.0079 15.6 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 CDO72902.1 - 0.46 10.2 21.2 0.0097 15.6 7.7 3.1 3 0 0 3 3 3 0 Right handed beta helix region Tropomyosin_1 PF12718.2 CDO72903.1 - 0.0013 18.5 13.1 0.0013 18.5 9.1 3.2 3 1 0 3 3 2 1 Tropomyosin like DUF3095 PF11294.3 CDO72903.1 - 0.0066 15.5 0.0 0.015 14.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3095) Reo_sigmaC PF04582.7 CDO72903.1 - 0.019 14.1 3.0 0.19 10.8 0.0 2.5 3 0 0 3 3 3 0 Reovirus sigma C capsid protein SBP_bac_7 PF03480.8 CDO72903.1 - 0.029 13.4 0.2 0.029 13.4 0.1 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 zf-CCCH PF00642.19 CDO72903.1 - 0.082 12.6 0.8 0.18 11.5 0.6 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CDO72903.1 - 0.11 12.5 2.2 0.19 11.7 1.5 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF342 PF03961.8 CDO72903.1 - 0.23 9.8 6.0 0.11 10.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) OmpH PF03938.9 CDO72903.1 - 0.35 10.8 28.0 2.6 7.9 0.6 3.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) COG2 PF06148.6 CDO72903.1 - 0.38 10.6 17.1 0.88 9.4 0.4 4.8 3 1 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 CDO72903.1 - 0.66 9.5 34.8 0.16 11.5 12.7 2.9 2 1 0 2 2 2 0 IncA protein Syntaxin_2 PF14523.1 CDO72903.1 - 0.68 10.0 15.5 0.65 10.0 0.8 3.5 3 1 0 4 4 3 0 Syntaxin-like protein AAA_13 PF13166.1 CDO72903.1 - 0.68 8.3 10.1 0.26 9.7 2.1 2.2 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 CDO72903.1 - 1.4 6.6 8.4 0.088 10.6 1.7 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CDO72903.1 - 2.2 8.6 14.5 0.12 12.7 3.5 3.4 4 0 0 4 4 3 0 Protein of unknown function (DUF972) TBPIP PF07106.8 CDO72903.1 - 4.3 6.8 16.5 0.13 11.8 2.6 3.7 4 1 1 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 CDO72903.1 - 6.4 5.6 19.4 0.071 12.0 5.4 2.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_PEP_C PF04513.7 CDO72903.1 - 6.8 6.5 9.1 11 5.8 0.1 4.0 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 CDO72903.1 - 7.3 5.5 17.2 0.11 11.5 4.0 2.6 2 0 0 2 2 2 0 Autophagy protein Apg6 Cytochrom_C552 PF02335.10 CDO72903.1 - 9.2 4.8 8.0 7.3 5.1 2.2 2.1 2 0 0 2 2 2 0 Cytochrome c552 ABC_tran PF00005.22 CDO72904.1 - 5.4e-06 26.7 0.0 8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.1 CDO72904.1 - 0.0037 17.1 0.0 0.051 13.5 0.0 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 CDO72904.1 - 0.0057 15.9 0.0 0.0064 15.7 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDO72904.1 - 0.048 13.6 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain Porin_3 PF01459.17 CDO72905.1 - 3.6e-73 246.2 2.0 4.1e-73 246.0 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin HSP70 PF00012.15 CDO72906.1 - 7.1e-276 915.9 2.3 8.1e-276 915.7 1.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CDO72906.1 - 1.9e-16 59.5 0.1 3.1e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CDO72906.1 - 0.0035 16.4 0.0 0.032 13.3 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CDO72906.1 - 0.004 16.7 0.0 0.0092 15.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain AAA_13 PF13166.1 CDO72906.1 - 0.0051 15.3 1.0 0.17 10.3 0.2 2.1 2 0 0 2 2 2 2 AAA domain DUF4582 PF15189.1 CDO72906.1 - 0.026 13.7 0.1 0.058 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) PhoD PF09423.5 CDO72907.1 - 5.2e-119 397.7 0.1 4.9e-118 394.5 0.1 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase AAA_33 PF13671.1 CDO72907.1 - 0.042 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PNGaseA PF12222.3 CDO72908.1 - 2.4e-75 254.0 2.4 3.2e-75 253.6 1.7 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Pmp3 PF01679.12 CDO72909.1 - 2.7e-16 58.9 5.0 3.6e-16 58.6 3.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Med19 PF10278.4 CDO72909.1 - 5.4 6.6 11.7 1.5 8.4 5.6 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 FBPase PF00316.15 CDO72911.1 - 3.6e-129 430.2 0.0 4.1e-129 430.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 CDO72911.1 - 0.0014 17.9 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family DUF2418 PF10332.4 CDO72912.1 - 1.1e-11 44.8 0.1 1.9e-11 44.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2418) DUF3552 PF12072.3 CDO72913.1 - 0.032 13.4 5.9 0.036 13.2 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF812 PF05667.6 CDO72914.1 - 0.002 16.7 3.4 0.002 16.7 2.4 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF812) AAA_13 PF13166.1 CDO72914.1 - 0.0073 14.8 5.4 0.044 12.2 1.4 2.1 2 0 0 2 2 2 1 AAA domain DUF719 PF05334.8 CDO72914.1 - 0.042 13.8 3.2 6.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Fib_alpha PF08702.5 CDO72914.1 - 0.12 12.5 0.2 0.12 12.5 0.1 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 CDO72914.1 - 0.15 11.8 2.2 4.2 7.1 0.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 CDO72914.1 - 1.2 9.4 8.1 0.54 10.5 0.3 3.7 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 CDO72914.1 - 1.7 8.4 6.9 4.4 7.1 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spectrin PF00435.16 CDO72914.1 - 1.9 8.8 26.1 0.078 13.2 4.1 4.0 3 1 0 3 3 3 0 Spectrin repeat DUF2408 PF10303.4 CDO72914.1 - 5.4 7.1 10.5 6.8 6.8 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2408) Bap31 PF05529.7 CDO72914.1 - 6.9 6.0 7.0 37 3.6 2.6 2.6 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Prenyltransf PF01255.14 CDO72915.1 - 4e-76 255.0 0.0 4.8e-76 254.7 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase zf-RING_2 PF13639.1 CDO72916.1 - 4.8e-05 23.1 5.0 4.8e-05 23.1 3.4 1.7 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.12 CDO72916.1 - 7.2e-05 22.1 0.4 0.00013 21.3 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-rbx1 PF12678.2 CDO72916.1 - 0.0034 17.4 1.5 0.0034 17.4 1.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger PHD PF00628.24 CDO72916.1 - 0.019 14.6 5.9 0.038 13.6 4.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 CDO72916.1 - 0.026 14.0 5.0 0.067 12.7 3.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CDO72916.1 - 0.042 13.8 5.9 0.11 12.5 4.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CDO72916.1 - 0.16 11.9 6.2 0.22 11.5 3.2 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 CDO72916.1 - 0.18 11.5 4.6 0.79 9.5 3.2 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 CDO72916.1 - 1.7 8.4 10.0 0.035 13.8 1.5 2.2 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 CDO72916.1 - 1.9 8.2 8.1 0.2 11.3 2.1 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Aldolase_II PF00596.16 CDO72917.1 - 1.9e-48 164.4 0.3 2.6e-48 164.0 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FTHFS PF01268.14 CDO72918.1 - 3.9e-262 870.2 0.2 5.5e-262 869.7 0.0 1.3 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CDO72918.1 - 1.3e-68 229.0 0.2 1.3e-68 229.0 0.1 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CDO72918.1 - 5.2e-37 126.4 0.8 1.9e-36 124.6 0.5 2.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Prefoldin PF02996.12 CDO72918.1 - 0.066 12.8 0.0 1.6 8.4 0.0 2.8 2 0 0 2 2 2 0 Prefoldin subunit GrpE PF01025.14 CDO72919.1 - 5.2e-44 149.7 0.3 8.9e-44 148.9 0.2 1.4 1 1 0 1 1 1 1 GrpE Chorismate_synt PF01264.16 CDO72919.1 - 0.01 14.3 0.0 0.023 13.1 0.0 1.6 1 1 1 2 2 2 0 Chorismate synthase IncA PF04156.9 CDO72919.1 - 0.14 11.7 4.8 0.21 11.1 3.3 1.2 1 0 0 1 1 1 0 IncA protein tRNA-synt_2d PF01409.15 CDO72920.1 - 5.3e-46 156.8 0.0 5.3e-26 91.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CDO72920.1 - 7.1e-06 26.1 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain E2_bind PF08825.5 CDO72921.1 - 6.8e-26 89.8 0.0 1.1e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain ThiF PF00899.16 CDO72921.1 - 5e-25 87.9 0.0 2.2e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 CDO72921.1 - 7.6e-25 86.2 0.4 1.4e-24 85.4 0.3 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CDO72921.1 - 1.2e-17 62.9 1.5 1.2e-17 62.9 1.1 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 CDO72921.1 - 0.0042 16.6 0.6 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 CDO72921.1 - 0.052 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HypA PF01155.14 CDO72921.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ecm33 PF12454.3 CDO72921.1 - 0.18 11.7 2.8 0.4 10.6 2.0 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein RTC PF01137.16 CDO72922.1 - 2.1e-68 229.5 0.0 2.4e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CDO72922.1 - 1.1e-11 44.6 0.6 1.6e-10 40.9 0.1 2.2 1 1 1 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain NPR2 PF06218.6 CDO72923.1 - 2e-100 336.4 0.2 5.1e-84 282.4 0.3 2.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 CDO72923.1 - 0.057 11.9 0.2 2.8 6.3 0.2 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 GCIP PF13324.1 CDO72924.1 - 4.4e-13 49.0 0.0 6.7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting zf-CCCH PF00642.19 CDO72924.1 - 0.0014 18.2 1.2 0.0033 17.0 0.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GMC_oxred_N PF00732.14 CDO72925.1 - 2.6e-42 145.0 0.0 6.5e-42 143.6 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO72925.1 - 1.6e-28 99.8 0.0 5.5e-22 78.6 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 CDO72925.1 - 1.7e-06 27.2 0.8 0.032 13.1 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDO72925.1 - 0.0023 17.9 0.2 0.006 16.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CDO72925.1 - 0.004 16.1 0.2 0.0063 15.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CDO72925.1 - 0.0069 15.2 2.1 0.042 12.6 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 CDO72925.1 - 0.066 11.6 0.2 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 CDO72925.1 - 0.11 12.3 0.6 0.47 10.3 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDO72925.1 - 0.14 11.2 0.1 0.3 10.1 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.20 CDO72926.1 - 4.8e-05 22.6 0.0 7.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CDO72926.1 - 0.00011 22.0 0.4 0.00012 21.9 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CDO72926.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CDO72926.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 CDO72926.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase OGG_N PF07934.7 CDO72928.1 - 8.1e-28 96.7 0.0 1.2e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CDO72928.1 - 3e-14 53.1 0.0 5.4e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CDO72928.1 - 0.14 11.9 0.1 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif NMT_C PF02799.10 CDO72929.1 - 4.8e-69 231.5 0.0 7.5e-69 230.9 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 CDO72929.1 - 3.2e-66 221.9 0.0 5.3e-66 221.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 CDO72929.1 - 7.5e-06 25.8 0.0 0.00015 21.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Cut8_N PF14482.1 CDO72929.1 - 7.7 6.6 8.6 20 5.2 6.0 1.7 1 1 0 1 1 1 0 Cut8 proteasome-binding domain UFD1 PF03152.9 CDO72930.1 - 6.7e-61 204.4 0.0 9.2e-61 204.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 CDO72930.1 - 0.0021 17.6 0.1 0.0083 15.7 0.0 1.9 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Cpn60_TCP1 PF00118.19 CDO72931.1 - 1.1e-141 472.7 12.0 1.3e-141 472.5 8.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Vps52 PF04129.7 CDO72931.1 - 0.026 13.0 0.2 0.15 10.5 0.1 1.9 2 0 0 2 2 2 0 Vps52 / Sac2 family DUF3599 PF12206.3 CDO72931.1 - 0.068 13.4 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) DSHCT PF08148.7 CDO72932.1 - 0.094 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain Adaptin_N PF01602.15 CDO72933.1 - 0.0016 16.8 0.0 0.0018 16.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Arteri_nucleo PF01481.11 CDO72933.1 - 0.044 13.8 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein RabGAP-TBC PF00566.13 CDO72934.1 - 1.9e-40 138.6 0.0 2.5e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mito_carr PF00153.22 CDO72935.1 - 1.2e-44 149.8 1.9 3.5e-15 55.4 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Rrn6 PF10214.4 CDO72935.1 - 0.0012 17.0 0.1 0.0014 16.8 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Ribosomal_L3 PF00297.17 CDO72937.1 - 3.2e-41 141.4 0.8 4.8e-40 137.6 0.6 2.2 1 1 0 1 1 1 1 Ribosomal protein L3 TrkA_C PF02080.16 CDO72939.1 - 0.04 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain MFS_1 PF07690.11 CDO72941.1 - 2e-34 118.8 52.3 1.1e-20 73.6 5.1 3.9 3 1 0 3 3 3 3 Major Facilitator Superfamily Cofilin_ADF PF00241.15 CDO72942.1 - 2.2e-10 40.5 0.0 2.4e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mannosyl_trans PF05007.8 CDO72943.1 - 1.3e-77 261.0 11.9 1.5e-77 260.7 8.2 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 CDO72943.1 - 2e-08 33.4 2.9 2e-08 33.4 2.0 2.1 2 0 0 2 2 2 2 GPI transamidase subunit PIG-U Arf PF00025.16 CDO72944.1 - 2.1e-43 147.5 0.0 7.7e-36 122.9 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.5 CDO72944.1 - 0.00018 20.7 0.0 0.0043 16.2 0.0 2.0 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CDO72944.1 - 0.011 14.4 0.2 0.091 11.4 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Miro PF08477.8 CDO72944.1 - 0.03 14.8 0.0 0.046 14.2 0.0 1.3 1 1 0 1 1 1 0 Miro-like protein UBN2_2 PF14227.1 CDO72946.1 - 1.1e-16 60.4 0.0 2.4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO72946.1 - 1.1e-14 54.2 0.0 1.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO72946.1 - 4.3e-10 39.3 0.0 6.8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO72946.1 - 5.5e-06 26.0 3.5 1.7e-05 24.5 2.4 1.9 1 0 0 1 1 1 1 Zinc knuckle DUF4219 PF13961.1 CDO72946.1 - 0.00033 19.9 0.3 0.00061 19.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC_5 PF14787.1 CDO72946.1 - 0.0058 16.0 5.1 0.014 14.8 3.6 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger eIF3g PF12353.3 CDO72946.1 - 0.041 13.8 0.6 0.072 13.0 0.4 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G RVP PF00077.15 CDO72946.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 CDO72946.1 - 0.22 11.2 2.1 0.38 10.4 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 CDO72947.1 - 6e-74 248.1 0.0 8.6e-74 247.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO72947.1 - 1.2e-18 67.3 0.0 7.5e-18 64.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 CDO72947.1 - 0.0061 16.0 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain ABC1 PF03109.11 CDO72948.1 - 9.6e-24 83.6 0.0 9.1e-14 51.4 0.0 2.6 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 CDO72948.1 - 0.0089 15.7 0.5 0.23 11.1 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_C48 PF02902.14 CDO72949.1 - 0.00099 18.7 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_transf_8 PF01501.15 CDO72950.1 - 1e-34 120.0 0.0 1.5e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CDO72950.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Apolipoprotein PF01442.13 CDO72951.1 - 0.0044 16.5 7.0 0.018 14.5 4.8 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.13 CDO72951.1 - 0.0092 15.7 5.3 0.0092 15.7 3.7 2.4 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) DUF883 PF05957.8 CDO72951.1 - 3.8 7.9 15.2 1.4 9.3 1.4 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) MFS_1 PF07690.11 CDO72952.1 - 2.5e-44 151.4 27.3 2.5e-44 151.4 18.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO72952.1 - 1.2e-15 57.0 6.9 1.2e-15 57.0 4.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Mating_N PF12731.2 CDO72954.1 - 1.2e-06 28.2 3.1 2.7e-06 27.1 2.2 1.6 1 0 0 1 1 1 1 Mating-type protein beta 1 PPV_E2_N PF00508.12 CDO72954.1 - 0.12 11.5 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 E2 (early) protein, N terminal Peptidase_M3 PF01432.15 CDO72955.1 - 7.1e-124 414.3 0.0 9.2e-124 413.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Herpes_gE PF02480.11 CDO72956.1 - 0.18 10.0 1.8 0.32 9.2 1.2 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NOA36 PF06524.7 CDO72956.1 - 6.4 5.9 5.6 10 5.2 3.9 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1754 PF08555.5 CDO72957.1 - 3e-14 53.4 7.8 3e-14 53.4 5.4 1.5 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF4191 PF13829.1 CDO72957.1 - 0.00078 18.6 0.1 0.0013 17.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) MCC-bdg_PDZ PF10506.4 CDO72957.1 - 0.058 13.2 1.9 0.092 12.5 1.3 1.3 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome VSG_B PF13206.1 CDO72957.1 - 0.89 8.6 6.6 1.1 8.3 4.6 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain Striatin PF08232.7 CDO72957.1 - 1.4 9.2 8.2 0.12 12.6 1.8 1.8 1 1 1 2 2 2 0 Striatin family DUF1751 PF08551.5 CDO72958.1 - 1.1e-27 96.2 5.6 2.2e-27 95.2 3.9 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Vps51 PF08700.6 CDO72958.1 - 9.4e-17 60.6 0.6 2.6e-16 59.2 0.4 1.8 1 0 0 1 1 1 1 Vps51/Vps67 DER1 PF04511.10 CDO72958.1 - 0.014 14.9 10.3 0.022 14.2 7.1 1.3 1 0 0 1 1 1 0 Der1-like family Rhomboid PF01694.17 CDO72958.1 - 2 8.4 9.0 4.2 7.3 6.2 1.5 1 0 0 1 1 1 0 Rhomboid family YwiC PF14256.1 CDO72959.1 - 0.051 13.6 6.2 0.031 14.3 2.9 1.7 2 0 0 2 2 2 0 YwiC-like protein SecE PF00584.15 CDO72960.1 - 1e-15 57.0 0.0 1.1e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex PPR_2 PF13041.1 CDO72961.1 - 4.3e-18 65.0 0.4 0.002 18.0 0.0 8.0 4 2 3 7 7 7 7 PPR repeat family PPR PF01535.15 CDO72961.1 - 4.6e-11 41.9 9.7 0.028 14.4 0.1 8.2 9 1 0 9 9 9 3 PPR repeat PPR_3 PF13812.1 CDO72961.1 - 1.8e-08 33.9 0.4 7.1 7.1 0.0 8.0 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 CDO72961.1 - 3.3e-06 26.4 1.3 0.014 14.8 0.0 5.1 6 0 0 6 6 6 2 PPR repeat MNE1 PF13762.1 CDO72961.1 - 0.023 14.7 0.0 0.12 12.4 0.0 2.2 1 1 0 1 1 1 0 Mitochondrial splicing apparatus component GDC-P PF02347.11 CDO72962.1 - 1.8e-181 603.5 0.0 8.9e-171 568.2 0.0 3.0 2 1 1 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 CDO72962.1 - 5.7e-06 25.6 0.1 1.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CDO72962.1 - 9.4e-05 21.3 0.2 0.00046 19.0 0.1 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DUF1741 PF08427.5 CDO72963.1 - 2.1e-26 92.8 0.3 8.1e-24 84.3 0.0 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1741) F-box-like PF12937.2 CDO72965.1 - 5.6e-06 25.9 0.0 1.7e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO72965.1 - 0.036 13.7 0.0 0.12 12.0 0.0 2.0 1 0 0 1 1 1 0 F-box domain AATase PF07247.7 CDO72966.1 - 0.31 9.5 0.0 0.48 8.9 0.0 1.4 1 1 0 1 1 1 0 Alcohol acetyltransferase TPT PF03151.11 CDO72967.1 - 3.6e-07 29.9 10.9 3.6e-07 29.9 7.5 2.6 2 1 1 3 3 3 1 Triose-phosphate Transporter family O-FucT PF10250.4 CDO72968.1 - 1.4e-08 34.2 0.0 3.5e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase F-box-like PF12937.2 CDO72969.1 - 0.0082 15.8 1.1 0.022 14.4 0.7 1.7 1 0 0 1 1 1 1 F-box-like Transglut_core2 PF13369.1 CDO72970.1 - 8.4e-12 44.8 0.0 1.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 CDO72970.1 - 0.01 15.5 0.1 0.033 13.9 0.0 1.9 2 0 0 2 2 2 0 F-box-like ApbA_C PF08546.6 CDO72971.1 - 5.1e-28 97.5 0.0 7.3e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CDO72971.1 - 4.6e-22 78.0 0.0 2.8e-21 75.5 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 CDO72971.1 - 0.047 13.4 0.0 7.1 6.3 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NmrA PF05368.8 CDO72971.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Aldo_ket_red PF00248.16 CDO72972.1 - 7.5e-51 172.6 0.0 8.7e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PB1 PF00564.19 CDO72973.1 - 1.7e-08 34.0 0.0 3.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 PB1 domain BID PF06393.6 CDO72973.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) Baculo_PEP_C PF04513.7 CDO72973.1 - 0.17 11.6 0.2 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 CDO72973.1 - 4.4 7.7 12.8 7.4 7.0 0.8 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) F-box-like PF12937.2 CDO72974.1 - 7.9e-09 35.1 1.0 7.9e-09 35.1 0.7 2.1 2 0 0 2 2 2 1 F-box-like Homeobox PF00046.24 CDO72975.1 - 3.4e-12 45.7 0.3 5.9e-12 45.0 0.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CDO72975.1 - 0.00022 20.8 0.0 0.00058 19.5 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Hepar_II_III PF07940.8 CDO72976.1 - 2.5e-11 43.5 0.8 6.2e-11 42.2 0.5 1.6 1 0 0 1 1 1 1 Heparinase II/III-like protein Na_H_Exchanger PF00999.16 CDO72976.1 - 0.17 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family Homeobox PF00046.24 CDO72977.1 - 5.4e-07 29.1 0.3 1.1e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 Homeobox domain Mito_fiss_reg PF05308.6 CDO72977.1 - 0.27 10.5 8.2 0.052 12.9 2.9 1.8 1 1 1 2 2 2 0 Mitochondrial fission regulator WD40 PF00400.27 CDO72978.1 - 1.6e-20 72.1 4.0 0.00047 19.9 0.0 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Zn_clus PF00172.13 CDO72979.1 - 5.8e-06 26.1 7.0 1.1e-05 25.2 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CDO72979.1 - 0.017 13.9 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF1515 PF07439.6 CDO72980.1 - 1 9.1 8.3 4.3 7.1 2.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Reo_sigmaC PF04582.7 CDO72980.1 - 1.1 8.3 13.5 1.1 8.4 4.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3439 PF11921.3 CDO72980.1 - 1.4 8.6 7.9 2.3 8.0 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4239 PF14023.1 CDO72980.1 - 1.6 8.0 7.3 2.9 7.1 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) AAA_13 PF13166.1 CDO72980.1 - 3.6 5.9 31.0 0.081 11.3 13.8 2.1 2 0 0 2 2 2 0 AAA domain BBP1_C PF15272.1 CDO72980.1 - 4 6.9 29.6 0.073 12.6 14.5 2.5 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF1664 PF07889.7 CDO72980.1 - 4.1 7.2 14.3 11 5.8 4.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 CDO72980.1 - 9.4 6.0 20.1 9.9 5.9 6.3 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec3_C PF09763.4 CDO72981.1 - 2.7e-121 405.9 16.5 1.9e-100 337.0 0.4 3.0 1 1 2 3 3 3 3 Exocyst complex component Sec3 Glyco_transf_21 PF13506.1 CDO72982.1 - 2.2e-24 85.6 2.8 1.2e-18 67.0 0.0 3.0 3 1 0 3 3 3 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 CDO72982.1 - 9.4e-21 74.6 0.0 1.2e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CDO72982.1 - 1.2e-07 31.6 0.0 2.5e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 CDO72982.1 - 1.8e-07 31.0 0.4 1.8e-07 31.0 0.2 1.6 1 1 1 2 2 2 1 Glycosyl transferase family group 2 F-box-like PF12937.2 CDO72983.1 - 3.4e-08 33.0 0.0 1.2e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 CDO72983.1 - 0.0043 16.9 2.5 0.55 10.4 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich repeat F-box PF00646.28 CDO72983.1 - 0.029 14.0 0.0 0.14 11.8 0.0 2.2 1 0 0 1 1 1 0 F-box domain LRR_1 PF00560.28 CDO72983.1 - 0.15 12.1 1.9 5.3 7.4 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 CDO72983.1 - 0.34 10.5 8.7 15 5.3 0.8 4.8 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CDO72983.1 - 0.89 10.0 5.7 15 6.2 0.0 4.8 5 1 0 5 5 5 0 Leucine rich repeat TatD_DNase PF01026.16 CDO72984.1 - 5.5e-39 133.9 0.0 8.7e-38 129.9 0.0 2.0 1 1 0 1 1 1 1 TatD related DNase Metallophos_2 PF12850.2 CDO72984.1 - 0.0062 16.3 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Amidohydro_2 PF04909.9 CDO72984.1 - 0.04 13.4 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase Radical_SAM PF04055.16 CDO72984.1 - 0.042 14.0 0.0 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Radical SAM superfamily Thiolase_N PF00108.18 CDO72985.1 - 2.8e-75 252.6 0.1 4.3e-75 252.1 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CDO72985.1 - 5.7e-08 32.2 0.0 1.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CDO72985.1 - 0.0065 15.9 0.6 0.1 12.0 0.0 2.8 2 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CDO72985.1 - 0.015 14.9 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Hepar_II_III PF07940.8 CDO72986.1 - 7.6e-08 32.2 0.3 1.7e-07 31.1 0.2 1.6 1 0 0 1 1 1 1 Heparinase II/III-like protein TFIIA PF03153.8 CDO72987.1 - 8.6 6.1 10.6 12 5.7 7.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF668 PF05003.7 CDO72988.1 - 0.083 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF668) Methyltransf_23 PF13489.1 CDO72989.1 - 8.1e-05 22.3 0.0 0.00026 20.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CDO72989.1 - 0.027 13.4 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.2 CDO72989.1 - 0.072 13.6 0.0 0.69 10.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain DUF1212 PF06738.7 CDO72990.1 - 1.3e-33 116.0 2.2 1.3e-33 116.0 1.5 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CDO72990.1 - 3.1e-13 49.7 11.3 3.1e-13 49.7 7.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) SNF2_N PF00176.18 CDO72991.1 - 7.7e-71 238.3 0.0 4.9e-70 235.6 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDO72991.1 - 5.2e-12 45.4 0.0 1.7e-10 40.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 CDO72991.1 - 9.3e-05 22.0 3.3 0.00022 20.8 2.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CDO72991.1 - 0.069 12.8 3.9 0.19 11.4 2.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 CDO72991.1 - 0.18 11.6 0.0 5.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 CDO72991.1 - 0.28 11.2 3.7 0.79 9.8 2.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MSV199 PF10553.4 CDO72991.1 - 0.31 10.9 0.3 2.2 8.1 0.1 2.0 2 0 0 2 2 2 0 MSV199 domain SPT6_acidic PF14632.1 CDO72991.1 - 2.3 8.4 5.8 0.46 10.6 0.9 2.1 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Glyco_hydro_20 PF00728.17 CDO72992.1 - 3.8e-15 55.9 0.0 9.4e-14 51.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 CDO72992.1 - 1.3e-11 45.0 0.1 4e-11 43.5 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 PDZ PF00595.19 CDO72992.1 - 0.027 14.6 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) dsrm PF00035.20 CDO72993.1 - 5.6e-09 36.4 0.1 1.4e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 CDO72993.1 - 5.2e-05 23.1 0.0 9.1e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like AcetDehyd-dimer PF09290.6 CDO72993.1 - 0.073 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation DUF684 PF05075.9 CDO72993.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF684) SNF2_N PF00176.18 CDO72994.1 - 4e-65 219.5 0.8 5.7e-65 219.0 0.6 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 CDO72994.1 - 6.3e-24 84.2 0.4 1.2e-23 83.4 0.3 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 CDO72994.1 - 7.5e-16 57.7 0.0 2.6e-15 56.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.1 CDO72994.1 - 5e-10 38.9 6.3 1.1e-07 31.2 0.2 3.4 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain DEAD PF00270.24 CDO72994.1 - 2.4e-06 27.1 0.0 4.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Chromo PF00385.19 CDO72994.1 - 0.0003 20.4 5.5 0.036 13.7 0.0 3.6 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain gpUL132 PF11359.3 CDO72994.1 - 0.33 10.2 2.3 1.4 8.2 0.7 2.5 2 0 0 2 2 2 0 Glycoprotein UL132 PHD PF00628.24 CDO72994.1 - 1.2 8.9 8.7 4.8 6.9 0.1 3.9 4 0 0 4 4 4 0 PHD-finger Sec8_exocyst PF04048.9 CDO72995.1 - 2e-35 121.4 1.6 4.4e-35 120.3 1.1 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 CDO72995.1 - 5.3e-11 41.9 1.5 1e-10 41.0 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 CDO72995.1 - 2.7e-05 24.0 0.1 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Complex1_LYR PF05347.10 CDO72996.1 - 0.0084 15.8 0.8 0.017 14.9 0.6 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CDO72996.1 - 0.012 15.7 0.3 0.027 14.6 0.2 1.6 1 0 0 1 1 1 0 Complex1_LYR-like Cellulase PF00150.13 CDO72997.1 - 1.7e-40 138.9 0.0 2.3e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 CDO72997.1 - 7.3e-12 44.7 8.2 1.6e-11 43.6 5.7 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Kelch_4 PF13418.1 CDO72998.1 - 3.1e-30 103.6 25.1 1.5e-08 34.2 0.4 6.6 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CDO72998.1 - 3.8e-30 103.3 21.9 1.9e-07 31.0 0.4 7.0 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 CDO72998.1 - 1e-27 95.5 13.4 1.2e-06 28.2 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 CDO72998.1 - 1.9e-25 87.9 20.2 4.9e-08 32.8 0.3 7.3 6 1 1 7 7 7 5 Kelch motif Kelch_1 PF01344.20 CDO72998.1 - 3e-25 87.4 16.0 2.8e-08 33.1 0.2 5.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CDO72998.1 - 3.2e-14 52.0 17.8 0.00096 18.8 0.4 6.4 6 1 0 6 6 6 4 Kelch motif PQQ_3 PF13570.1 CDO72998.1 - 2.6 8.4 16.2 11 6.4 0.3 5.7 5 1 1 6 6 6 0 PQQ-like domain Esterase PF00756.15 CDO72999.1 - 6.9e-39 133.7 0.0 2.4e-37 128.7 0.0 2.1 2 0 0 2 2 2 1 Putative esterase PGAP1 PF07819.8 CDO72999.1 - 1.2e-09 38.1 0.0 8.3e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CDO72999.1 - 9.7e-09 35.1 0.0 0.0039 16.9 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO72999.1 - 1.3e-06 28.4 0.1 8.2e-05 22.5 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 CDO72999.1 - 0.0023 17.0 0.0 0.061 12.3 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 CDO72999.1 - 0.0045 16.6 0.0 1.9 8.0 0.0 2.8 3 0 0 3 3 3 1 Lipase (class 3) Abhydrolase_1 PF00561.15 CDO72999.1 - 0.01 15.4 0.1 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.9 CDO72999.1 - 0.018 14.3 0.1 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) LCAT PF02450.10 CDO72999.1 - 0.05 12.5 0.0 0.29 10.0 0.0 1.9 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Choline_kinase PF01633.15 CDO72999.1 - 0.06 12.9 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Thioesterase PF00975.15 CDO72999.1 - 0.078 13.1 0.6 0.79 9.8 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain MMR_HSR1 PF01926.18 CDO73000.1 - 1.2e-15 57.4 0.0 3.8e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CDO73000.1 - 4.1e-05 22.8 0.0 8.3e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CDO73000.1 - 4.6e-05 22.7 0.0 8.7e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 CDO73000.1 - 0.005 15.9 0.0 0.0093 15.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 CDO73000.1 - 0.0074 16.1 0.1 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 CDO73000.1 - 0.011 16.2 0.0 0.032 14.7 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein EF_TS PF00889.14 CDO73001.1 - 6.3e-16 58.3 0.0 1.5e-15 57.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor TS UBA PF00627.26 CDO73001.1 - 7.8e-06 25.5 0.1 1.9e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CDO73001.1 - 0.0005 19.5 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Taxilin PF09728.4 CDO73002.1 - 3.6e-16 59.1 29.7 1.5e-08 34.1 13.9 2.5 2 1 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.3 CDO73002.1 - 2.9e-07 30.0 0.6 0.0055 16.3 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CDO73002.1 - 0.057 12.8 0.0 1.1 8.7 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin family Microtub_assoc PF07989.6 CDO73002.1 - 4.1 7.3 16.7 1.2 8.9 0.8 3.2 2 1 1 3 3 3 0 Microtubule associated UDPGP PF01704.13 CDO73003.1 - 1.2e-45 155.7 0.0 1.6e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CDO73003.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain Lum_binding PF00677.12 CDO73005.1 - 1.1e-37 127.7 0.0 2.7e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain SspH PF08141.7 CDO73005.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Small acid-soluble spore protein H family DUF148 PF02520.12 CDO73006.1 - 0.5 10.1 2.2 0.87 9.4 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 Ribosomal_60s PF00428.14 CDO73006.1 - 3.2 8.2 6.1 0.16 12.3 0.3 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Myosin_head PF00063.16 CDO73007.1 - 6.4e-229 761.5 0.2 1.1e-228 760.8 0.1 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CDO73007.1 - 1.9e-47 161.1 0.0 3.3e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_9 PF14604.1 CDO73007.1 - 1.3e-11 43.9 0.4 3.3e-11 42.5 0.3 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CDO73007.1 - 2.5e-10 39.7 0.0 8.3e-10 38.0 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CDO73007.1 - 1.2e-09 37.4 0.9 2.4e-09 36.4 0.6 1.6 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 CDO73007.1 - 1.6e-05 24.9 0.6 5.8e-05 23.1 0.4 2.0 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 CDO73007.1 - 0.0075 16.4 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDO73007.1 - 0.023 13.7 0.0 0.065 12.3 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 CDO73007.1 - 0.029 15.1 0.0 0.19 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain SH3_4 PF06347.8 CDO73007.1 - 0.036 13.5 0.3 0.089 12.3 0.2 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Hpr_kinase_C PF07475.7 CDO73007.1 - 0.041 13.2 1.0 4.4 6.5 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.1 CDO73007.1 - 0.077 13.3 0.1 0.78 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CDO73007.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CDO73007.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain UNC45-central PF11701.3 CDO73008.1 - 1.3e-13 50.9 0.0 5.8e-13 48.7 0.0 2.2 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central U3snoRNP10 PF12397.3 CDO73008.1 - 0.011 15.7 0.9 1.5 8.7 0.1 3.4 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 CDO73008.1 - 0.088 12.9 6.6 15 6.0 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.1 CDO73008.1 - 0.17 12.1 19.1 0.66 10.3 2.5 5.7 4 2 2 6 6 6 0 HEAT repeats Gcd10p PF04189.8 CDO73009.1 - 7.3e-72 242.0 0.0 1.5e-70 237.6 0.0 2.0 1 1 0 1 1 1 1 Gcd10p family p450 PF00067.17 CDO73010.1 - 6.1e-54 183.2 0.0 9.3e-54 182.6 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 UCR_6-4kD PF08997.5 CDO73010.1 - 0.14 11.8 0.2 1.4 8.6 0.2 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Ceramidase PF05875.7 CDO73011.1 - 2.6e-71 239.8 9.4 2.9e-71 239.6 6.5 1.0 1 0 0 1 1 1 1 Ceramidase BRCA-2_OB1 PF09103.5 CDO73012.1 - 9.8e-31 105.8 0.0 1.6e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 CDO73012.1 - 8.4e-05 22.2 0.1 0.00017 21.1 0.1 1.5 1 0 0 1 1 1 1 BRCA2, helical Peptidase_M16 PF00675.15 CDO73014.1 - 4.9e-40 136.7 0.0 1.2e-39 135.4 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CDO73014.1 - 1.7e-33 115.8 0.0 3.7e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain APC_crr PF05923.7 CDO73014.1 - 0.037 13.6 0.1 6.2 6.5 0.1 2.7 2 0 0 2 2 2 0 APC cysteine-rich region Transposase_21 PF02992.9 CDO73015.1 - 1e-38 132.7 0.0 2.7e-38 131.3 0.0 1.7 1 1 1 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 CDO73015.1 - 2.7e-06 26.8 0.0 9.6e-06 25.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) DUF4140 PF13600.1 CDO73016.1 - 0.24 11.8 12.2 0.39 11.1 8.1 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.6 CDO73016.1 - 0.45 9.1 4.5 0.59 8.7 3.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MalF_P2 PF14785.1 CDO73016.1 - 0.53 10.1 3.3 0.7 9.7 2.3 1.2 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain DUF3138 PF11336.3 CDO73016.1 - 0.61 8.1 7.4 0.67 8.0 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MscS_TM PF12794.2 CDO73016.1 - 1.2 7.6 8.9 1.9 7.0 6.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF3584 PF12128.3 CDO73016.1 - 3.2 4.9 14.6 3.8 4.7 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 CDO73016.1 - 5.3 5.8 7.8 8.2 5.2 5.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_UL25 PF01499.11 CDO73016.1 - 9 4.4 11.8 11 4.1 8.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family FPN1 PF06963.7 CDO73018.1 - 1.2e-83 280.8 3.4 1.4e-83 280.6 2.4 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) CreD PF06123.7 CDO73018.1 - 0.051 12.0 0.6 0.083 11.4 0.4 1.3 1 0 0 1 1 1 0 Inner membrane protein CreD Nexin_C PF08628.7 CDO73019.1 - 8.9e-29 99.8 0.1 2.6e-27 95.1 0.0 3.1 2 0 0 2 2 2 1 Sorting nexin C terminal PXA PF02194.10 CDO73019.1 - 1.5e-27 96.3 0.1 1.5e-27 96.3 0.0 3.8 4 1 1 5 5 5 1 PXA domain PX PF00787.19 CDO73019.1 - 2e-18 66.2 0.1 1e-17 63.9 0.0 2.3 3 0 0 3 3 3 1 PX domain RGS PF00615.14 CDO73019.1 - 2.5e-11 43.7 0.2 3.7e-10 39.9 0.1 2.9 3 0 0 3 3 3 1 Regulator of G protein signaling domain Isy1 PF06246.7 CDO73019.1 - 0.0058 16.0 0.1 0.0058 16.0 0.0 2.3 2 1 0 2 2 2 1 Isy1-like splicing family Mito_carr PF00153.22 CDO73020.1 - 5e-24 83.8 0.3 5.9e-12 45.1 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Glyco_hydro_7 PF00840.15 CDO73021.1 - 1.2e-215 715.8 21.2 1.4e-215 715.6 14.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Filament PF00038.16 CDO73022.1 - 0.0033 16.9 37.1 0.0033 16.9 25.7 10.2 1 1 7 9 9 9 3 Intermediate filament protein ATG16 PF08614.6 CDO73022.1 - 0.0033 17.2 17.8 0.0033 17.2 12.3 12.4 2 2 8 10 10 10 1 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 CDO73022.1 - 2.2 7.3 102.9 0.0073 15.5 3.3 9.6 3 2 4 9 9 9 0 Reovirus sigma C capsid protein DAO PF01266.19 CDO73023.1 - 7.1e-20 71.2 0.0 1.1e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CDO73023.1 - 0.01 16.2 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CDO73023.1 - 0.018 15.1 0.0 0.088 12.9 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 CDO73023.1 - 0.025 14.5 0.1 0.06 13.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 CDO73023.1 - 0.038 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 CDO73023.1 - 0.042 12.9 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 CDO73023.1 - 0.054 13.3 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CDO73023.1 - 0.062 12.9 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 CDO73023.1 - 0.077 12.0 0.0 0.95 8.4 0.1 2.3 3 0 0 3 3 3 0 FAD binding domain Saccharop_dh PF03435.13 CDO73023.1 - 0.095 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 CDO73023.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Transposase_21 PF02992.9 CDO73026.1 - 3.9e-16 58.8 0.0 6.9e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO73026.1 - 0.0005 19.5 0.0 0.00089 18.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) FGF-BP1 PF06473.7 CDO73026.1 - 0.05 13.2 0.7 0.094 12.3 0.5 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) NUC130_3NT PF08158.7 CDO73026.1 - 0.93 9.8 3.5 0.81 10.0 0.2 2.5 3 0 0 3 3 3 0 NUC130/3NT domain zf-ribbon_3 PF13248.1 CDO73026.1 - 2 7.7 9.9 0.021 13.9 1.5 1.8 2 0 0 2 2 2 0 zinc-ribbon domain BTB PF00651.26 CDO73029.1 - 0.019 14.9 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain TPR_10 PF13374.1 CDO73031.1 - 0.31 11.0 2.2 0.35 10.8 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat IncA PF04156.9 CDO73031.1 - 2.5 7.6 4.8 5.6 6.5 0.0 2.5 3 0 0 3 3 3 0 IncA protein Transposase_21 PF02992.9 CDO73032.1 - 2.5e-11 43.1 0.0 5.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO73032.1 - 0.00015 21.1 0.2 0.00028 20.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Fumble PF03630.9 CDO73033.1 - 1.5e-110 369.2 0.1 2.3e-104 348.9 0.2 2.9 2 1 0 2 2 2 2 Fumble Homeobox PF00046.24 CDO73034.1 - 3.3e-48 161.1 17.3 9.1e-17 60.4 0.7 3.4 3 0 0 3 3 3 3 Homeobox domain Homeobox_KN PF05920.6 CDO73034.1 - 9.5e-15 54.0 1.1 0.0013 18.3 0.0 3.8 3 0 0 3 3 3 3 Homeobox KN domain Homez PF11569.3 CDO73034.1 - 0.00012 21.0 0.4 0.84 8.7 0.0 3.6 3 0 0 3 3 3 3 Homeodomain leucine-zipper encoding, Homez SART-1 PF03343.8 CDO73034.1 - 0.00057 18.3 5.1 0.11 10.7 0.6 3.0 3 0 0 3 3 3 2 SART-1 family HTH_3 PF01381.17 CDO73034.1 - 0.00058 19.6 0.2 5 7.0 0.0 3.7 3 0 0 3 3 3 2 Helix-turn-helix ADH_N PF08240.7 CDO73035.1 - 4.9e-26 90.6 2.6 9.8e-26 89.6 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO73035.1 - 3.7e-17 62.0 0.1 1.6e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO73035.1 - 0.00012 22.9 0.0 0.00025 21.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CDO73035.1 - 0.00033 19.8 0.3 0.00054 19.1 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CDO73035.1 - 0.0011 18.5 0.1 0.0022 17.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 CDO73035.1 - 0.095 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Chitin_synth_1 PF01644.12 CDO73036.1 - 1.3e-77 259.2 0.2 1.9e-77 258.6 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 CDO73036.1 - 3e-25 88.6 0.3 1.2e-20 73.4 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 CDO73036.1 - 2.5e-22 78.3 0.0 6.5e-22 77.0 0.0 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 CDO73036.1 - 3.5e-08 33.3 0.2 3.5e-08 33.3 0.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CDO73036.1 - 3.6e-07 30.2 0.0 2.3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Fibrinogen_aC PF12160.3 CDO73036.1 - 0.016 14.6 0.1 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha C domain Pkinase PF00069.20 CDO73037.1 - 1.3e-37 129.3 0.0 1.7e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73037.1 - 1.3e-13 50.6 0.0 2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO73037.1 - 4.7e-05 23.2 0.9 0.0023 17.7 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CDO73037.1 - 0.015 14.0 0.1 0.022 13.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Adaptin_N PF01602.15 CDO73038.1 - 1.8e-116 389.5 0.0 3e-116 388.8 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CDO73038.1 - 1.6e-57 193.5 1.0 3.1e-57 192.6 0.7 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain cNMP_binding PF00027.24 CDO73038.1 - 3.1e-39 132.6 0.1 4.1e-18 64.9 0.0 5.2 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 CDO73038.1 - 4.6e-19 69.1 1.9 2.6e-13 50.3 0.5 2.9 2 0 0 2 2 2 2 Patatin-like phospholipase HEAT_2 PF13646.1 CDO73038.1 - 4.1e-12 46.2 4.6 0.0042 17.3 0.1 6.7 3 2 3 6 6 6 2 HEAT repeats HEAT PF02985.17 CDO73038.1 - 0.047 13.7 7.9 30 5.0 0.2 6.0 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.2 CDO73038.1 - 0.15 11.8 3.6 1.7 8.4 0.2 3.7 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ISG65-75 PF11727.3 CDO73038.1 - 0.69 8.9 0.1 19 4.1 0.0 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein Sec1 PF00995.18 CDO73039.1 - 6.8e-102 341.9 0.0 2.6e-101 339.9 0.0 1.7 1 1 1 2 2 2 1 Sec1 family DUF3136 PF11334.3 CDO73039.1 - 0.024 14.0 0.1 0.77 9.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) MobC PF05713.6 CDO73039.1 - 0.049 13.6 0.6 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) SpoIIIAH PF12685.2 CDO73039.1 - 0.2 11.1 0.9 2.8 7.3 0.0 2.9 3 0 0 3 3 3 0 SpoIIIAH-like protein YABBY PF04690.8 CDO73040.1 - 8.1e-07 29.4 0.1 9.2e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.14 CDO73040.1 - 0.011 16.0 0.4 0.016 15.4 0.3 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box DUF1014 PF06244.7 CDO73040.1 - 0.14 12.3 1.7 0.17 12.0 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1014) LRR_6 PF13516.1 CDO73041.1 - 6.7e-05 22.5 0.3 2.2 8.5 0.0 6.0 7 0 0 7 7 7 1 Leucine Rich repeat F-box-like PF12937.2 CDO73041.1 - 0.00067 19.3 1.4 0.0012 18.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like Sas10_Utp3 PF04000.10 CDO73042.1 - 6.4e-16 58.3 0.1 1.3e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family UPF0184 PF03670.8 CDO73042.1 - 0.058 13.5 0.9 0.4 10.8 0.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) TraF_2 PF13729.1 CDO73042.1 - 0.1 11.4 4.4 0.64 8.7 0.4 2.3 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein YABBY PF04690.8 CDO73042.1 - 0.16 12.2 0.2 0.16 12.2 0.2 1.8 2 0 0 2 2 2 0 YABBY protein SF3b10 PF07189.6 CDO73043.1 - 2.4e-33 113.7 0.0 3e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Methyltransf_11 PF08241.7 CDO73044.1 - 3.8e-13 49.7 0.0 9.2e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO73044.1 - 2.5e-11 43.5 0.0 4.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDO73044.1 - 5.9e-09 35.3 0.0 9.6e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CDO73044.1 - 1.2e-08 35.5 0.0 3e-08 34.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO73044.1 - 1.4e-08 35.1 0.0 3.6e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO73044.1 - 4.4e-08 33.4 0.0 8.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO73044.1 - 1.3e-06 28.0 0.0 2.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO73044.1 - 8.4e-05 22.5 1.2 0.00077 19.4 0.0 2.9 3 1 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 CDO73044.1 - 0.013 14.9 0.0 0.05 12.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 CDO73044.1 - 0.015 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 CDO73044.1 - 0.095 12.3 0.0 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase Mg_trans_NIPA PF05653.9 CDO73045.1 - 1.7e-76 257.0 13.7 3.3e-42 144.4 2.7 2.0 1 1 1 2 2 2 2 Magnesium transporter NIPA Cu-oxidase PF00394.17 CDO73046.1 - 8.5e-50 168.7 0.2 5.4e-48 162.8 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 CDO73046.1 - 3.3e-40 136.4 1.2 1.1e-38 131.5 0.3 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CDO73046.1 - 3.6e-35 120.4 10.4 4.7e-33 113.6 0.2 3.6 3 1 0 3 3 3 2 Multicopper oxidase DUF3992 PF13157.1 CDO73046.1 - 0.11 12.7 0.1 27 5.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3992) WLM PF08325.5 CDO73047.1 - 3.2e-44 151.0 0.0 5.5e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 CDO73047.1 - 8e-05 21.6 0.8 8e-05 21.6 0.5 3.1 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 CDO73047.1 - 0.0011 18.7 3.3 0.0038 17.0 2.5 1.8 1 1 1 2 2 2 1 Protein of unknown function DUF45 zf-Sec23_Sec24 PF04810.10 CDO73047.1 - 0.0056 16.2 2.2 13 5.4 0.1 3.4 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger DZR PF12773.2 CDO73047.1 - 0.029 14.1 5.1 0.053 13.3 3.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-MIZ PF02891.15 CDO73047.1 - 0.12 11.8 3.8 8.1 6.0 0.0 3.1 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger OrfB_Zn_ribbon PF07282.6 CDO73047.1 - 0.61 9.7 3.4 16 5.2 1.2 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF4193 PF13834.1 CDO73047.1 - 2.1 8.5 4.7 1.2 9.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4193) DUF605 PF04652.11 CDO73047.1 - 7.4 5.8 15.2 10 5.3 10.5 1.1 1 0 0 1 1 1 0 Vta1 like PHD PF00628.24 CDO73047.1 - 8.4 6.1 8.9 12 5.7 0.0 3.1 2 1 1 3 3 3 0 PHD-finger zf-4CXXC_R1 PF10497.4 CDO73047.1 - 9 6.4 9.1 6.6 6.9 1.4 2.4 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Bot1p PF12298.3 CDO73048.1 - 4.8e-24 85.2 0.0 7.9e-24 84.5 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Cpn60_TCP1 PF00118.19 CDO73049.1 - 6.1e-142 473.6 0.7 7.5e-142 473.3 0.5 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MFS_1 PF07690.11 CDO73049.1 - 3.3e-18 65.5 21.5 3.3e-18 65.5 14.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SNF2_N PF00176.18 CDO73050.1 - 1.8e-64 217.4 0.0 2.5e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 CDO73050.1 - 3.6e-15 55.7 0.0 1.4e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 HIRAN domain Helicase_C PF00271.26 CDO73050.1 - 9.5e-13 47.8 0.0 2.1e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO73050.1 - 2.5e-08 33.6 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 CDO73050.1 - 1.3e-06 27.9 13.8 2.4e-06 27.0 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO73050.1 - 2e-06 27.7 14.4 3.9e-06 26.7 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 CDO73050.1 - 7.6e-06 25.8 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 CDO73050.1 - 1.9e-05 24.3 12.0 1.9e-05 24.3 8.4 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CDO73050.1 - 0.00025 20.6 11.1 0.00045 19.8 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 CDO73050.1 - 0.00035 20.0 7.7 0.00062 19.2 5.4 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 CDO73050.1 - 0.0024 17.7 14.6 0.0044 16.8 10.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD_2 PF06733.10 CDO73050.1 - 0.0098 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 zf-RING_5 PF14634.1 CDO73050.1 - 0.019 14.6 12.6 0.034 13.8 8.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Patched PF02460.13 CDO73050.1 - 0.21 9.4 0.0 0.32 8.8 0.0 1.1 1 0 0 1 1 1 0 Patched family zf-Nse PF11789.3 CDO73050.1 - 0.25 10.9 6.5 0.59 9.6 4.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 CDO73050.1 - 0.28 10.9 5.9 0.84 9.4 4.1 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_clus PF00172.13 CDO73051.1 - 1.9e-07 30.8 5.8 2.7e-07 30.3 4.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HLH PF00010.21 CDO73052.1 - 2e-06 27.3 0.0 5.1e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAT1 PF09770.4 CDO73052.1 - 0.2 9.8 13.5 0.23 9.6 9.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cu-oxidase PF00394.17 CDO73053.1 - 2.5e-46 157.4 0.2 8.2e-45 152.5 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CDO73053.1 - 1.5e-40 137.8 4.7 5e-36 123.2 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CDO73053.1 - 3.2e-38 130.0 0.3 3e-36 123.7 0.1 2.6 2 0 0 2 2 2 1 Multicopper oxidase Glyco_hydro_3 PF00933.16 CDO73054.1 - 1e-55 188.8 0.0 6.1e-55 186.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CDO73054.1 - 8.5e-48 162.8 0.0 1.2e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CDO73054.1 - 8.7e-07 28.7 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain BSP PF04450.7 CDO73055.1 - 1.6e-35 122.4 0.0 3.3e-25 88.7 0.0 2.6 2 1 0 2 2 2 2 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 CDO73055.1 - 0.00045 20.2 0.0 0.001 19.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 CDO73055.1 - 0.0036 16.9 0.1 0.0049 16.5 0.1 1.2 1 0 0 1 1 1 1 SprT-like family NIF PF03031.13 CDO73056.1 - 1.3e-05 24.9 0.3 0.028 14.0 0.0 2.8 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase BRCT PF00533.21 CDO73056.1 - 6.9e-05 22.9 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CDO73056.1 - 0.00011 21.9 0.0 0.00088 19.0 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain adh_short PF00106.20 CDO73057.1 - 3e-25 89.0 0.2 4.9e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO73057.1 - 5.1e-16 59.1 0.0 6.7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 CDO73057.1 - 9.6e-07 28.2 0.0 0.0002 20.5 0.0 2.4 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) KR PF08659.5 CDO73057.1 - 0.00029 20.5 0.3 0.001 18.7 0.2 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CDO73057.1 - 0.00061 19.8 0.2 0.00098 19.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Proho_convert PF12177.3 CDO73057.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Prohormone convertase enzyme APH PF01636.18 CDO73059.1 - 1e-17 64.6 0.2 1.4e-17 64.2 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO73059.1 - 4.5e-05 23.1 0.0 8.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 CDO73059.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 CDO73059.1 - 0.15 11.3 0.0 0.79 9.0 0.0 1.8 2 0 0 2 2 2 0 RIO1 family adh_short PF00106.20 CDO73060.1 - 9e-30 103.7 0.2 1.7e-29 102.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO73060.1 - 3.5e-19 69.5 0.0 4.4e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 CDO73060.1 - 2.8e-10 39.8 0.0 1.5e-09 37.4 0.0 2.2 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 CDO73060.1 - 4.3e-07 29.7 0.9 2.1e-06 27.5 0.6 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO73060.1 - 7.8e-06 25.4 0.1 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO73060.1 - 2.1e-05 24.5 0.1 4.7e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CDO73060.1 - 0.012 14.5 0.1 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.10 CDO73060.1 - 0.066 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein EF-hand_6 PF13405.1 CDO73061.1 - 9.7e-12 43.7 2.0 5.5e-06 25.8 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CDO73061.1 - 2.1e-10 39.1 1.5 9.1e-06 24.6 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 CDO73061.1 - 2.8e-09 36.9 1.1 8e-05 22.6 0.0 2.7 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CDO73061.1 - 0.00092 18.4 1.2 0.0021 17.3 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.1 CDO73061.1 - 0.082 12.8 0.0 5.4 7.0 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.1 CDO73061.1 - 0.53 9.9 4.3 0.62 9.7 0.1 2.9 3 2 2 5 5 5 0 EF-hand domain pair DUF3105 PF11303.3 CDO73062.1 - 0.064 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) NPR3 PF03666.8 CDO73062.1 - 3 6.2 6.2 4.2 5.7 4.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-C2H2 PF00096.21 CDO73064.1 - 8.6e-09 35.2 18.2 3.3e-05 23.9 0.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO73064.1 - 0.0004 20.5 4.4 0.0004 20.5 3.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CDO73064.1 - 0.0059 16.7 0.1 0.0059 16.7 0.1 3.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CDO73064.1 - 0.02 15.0 0.3 0.02 15.0 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CDO73064.1 - 0.024 14.9 1.2 0.024 14.9 0.8 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3591 PF12157.3 CDO73065.1 - 5.4e-182 605.2 0.8 8.4e-182 604.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) PA28_beta PF02252.13 CDO73066.1 - 3.6e-27 94.6 2.9 1.1e-25 89.8 2.0 2.1 1 1 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 CDO73066.1 - 0.00011 22.2 0.1 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit WD40 PF00400.27 CDO73067.1 - 1.6e-24 84.8 11.0 4.8e-08 32.5 0.2 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CDO73067.1 - 1.6e-05 24.6 0.0 4.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 CDO73067.1 - 2.2e-05 24.2 0.4 0.0004 20.1 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 CDO73067.1 - 0.048 11.4 0.1 0.15 9.8 0.0 1.7 1 1 0 1 1 1 0 IKI3 family MAPEG PF01124.13 CDO73068.1 - 6.8e-23 80.6 0.5 8.1e-23 80.4 0.3 1.1 1 0 0 1 1 1 1 MAPEG family Transthyretin PF00576.16 CDO73070.1 - 2e-29 101.7 0.1 5.2e-29 100.3 0.1 1.6 1 1 0 1 1 1 1 HIUase/Transthyretin family RabGAP-TBC PF00566.13 CDO73072.1 - 3.7e-27 95.2 0.0 4.8e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nop52 PF05997.7 CDO73074.1 - 6.3e-66 221.9 0.0 1.2e-65 221.0 0.0 1.4 2 0 0 2 2 2 1 Nucleolar protein,Nop52 MMS19_N PF14500.1 CDO73074.1 - 2e-05 24.0 0.0 3.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II Spc97_Spc98 PF04130.8 CDO73075.1 - 4.7e-68 229.8 0.0 9e-68 228.9 0.0 1.5 1 0 0 1 1 1 1 Spc97 / Spc98 family HMGL-like PF00682.14 CDO73076.1 - 1.3e-71 241.0 0.4 2e-71 240.4 0.2 1.3 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.1 CDO73076.1 - 0.05 13.7 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 FliG N-terminal domain Pyrophosphatase PF00719.14 CDO73077.1 - 2.1e-54 183.2 0.1 2.6e-54 182.8 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase GldM_C PF12080.3 CDO73078.1 - 0.0076 16.2 0.0 0.13 12.1 0.0 2.8 3 0 0 3 3 3 1 GldM C-terminal domain I-set PF07679.11 CDO73078.1 - 0.02 14.7 0.1 1 9.2 0.0 3.5 5 0 0 5 5 5 0 Immunoglobulin I-set domain PBP1_TM PF14812.1 CDO73078.1 - 1.9 8.8 4.3 3.7 7.9 2.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AMP-binding PF00501.23 CDO73079.1 - 7.8e-36 123.3 0.0 1.8e-28 99.0 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.20 CDO73079.1 - 2.3e-12 46.9 0.2 5.8e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 CDO73079.1 - 6.1e-12 46.3 0.9 7.5e-05 23.6 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Hexapep PF00132.19 CDO73079.1 - 1.5e-09 36.9 2.5 0.007 15.8 0.0 5.9 6 0 0 6 6 6 2 Bacterial transferase hexapeptide (six repeats) Thioredoxin PF00085.15 CDO73080.1 - 9.9e-27 92.6 0.1 1.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CDO73080.1 - 1.7e-07 31.3 0.3 9e-07 29.0 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDO73080.1 - 9.3e-07 28.8 0.1 0.0003 20.8 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 CDO73080.1 - 1.7e-05 24.4 0.0 2.2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CDO73080.1 - 0.00042 19.9 0.1 0.0007 19.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 CDO73080.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like DUF2847 PF11009.3 CDO73080.1 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) TraF PF13728.1 CDO73080.1 - 0.057 12.8 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Redoxin PF08534.5 CDO73080.1 - 0.099 12.1 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Redoxin Histone PF00125.19 CDO73081.1 - 9.1e-14 51.3 0.1 1.1e-13 51.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CDO73081.1 - 3.2e-05 24.0 0.0 4.2e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CDO73081.1 - 9.1e-05 22.3 0.1 0.00013 21.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CDO73081.1 - 0.00079 19.4 0.1 0.0015 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CDO73081.1 - 0.055 12.7 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 CDO73081.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Kelch_4 PF13418.1 CDO73082.1 - 8.2e-16 57.5 1.0 3.9e-08 32.9 0.0 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CDO73082.1 - 7.8e-13 48.2 15.6 0.00049 20.1 0.0 7.1 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CDO73082.1 - 8.2e-11 41.6 2.9 0.014 15.3 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CDO73082.1 - 4.3e-06 26.6 0.1 0.0057 16.7 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 CDO73082.1 - 1.2e-05 24.7 0.0 6.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 CDO73082.1 - 9.8e-05 21.9 0.1 1.5 8.7 0.0 3.9 3 1 0 3 3 3 2 Kelch motif Arg_tRNA_synt_N PF03485.11 CDO73083.1 - 0.18 12.3 0.0 0.63 10.6 0.0 1.9 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain COesterase PF00135.23 CDO73084.1 - 2.4e-73 247.6 0.0 5.7e-66 223.3 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 CDO73084.1 - 0.0001 21.9 0.1 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Exo_endo_phos PF03372.18 CDO73085.1 - 4.1e-27 95.7 0.1 5.2e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FA_desaturase PF00487.19 CDO73085.1 - 1.5 8.2 6.3 3.2 7.1 4.3 1.5 1 0 0 1 1 1 0 Fatty acid desaturase Abhydrolase_3 PF07859.8 CDO73086.1 - 4.3e-50 170.2 0.1 7e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CDO73086.1 - 1.1e-14 53.9 0.0 1e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CDO73086.1 - 5.8e-05 22.8 0.0 9.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CDO73086.1 - 0.1 11.3 0.0 7.8 5.0 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_S9 PF00326.16 CDO73086.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4106 PF13388.1 CDO73086.1 - 3.3 6.5 6.0 4.8 6.0 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Peptidase_M24 PF00557.19 CDO73087.1 - 4.4e-41 140.7 0.0 5.5e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24 PF00557.19 CDO73088.1 - 1.1e-37 129.6 0.0 1.4e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 RibD_C PF01872.12 CDO73089.1 - 3e-28 98.8 0.0 1.7e-27 96.3 0.0 2.1 1 1 0 1 1 1 1 RibD C-terminal domain DUF959 PF06121.9 CDO73089.1 - 0.031 13.9 0.0 0.65 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF959) RhoGEF PF00621.15 CDO73090.1 - 1.7e-06 28.0 0.0 6e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain ZZ PF00569.12 CDO73092.1 - 2.1e-55 184.0 81.7 7.3e-12 44.6 6.2 6.3 6 0 0 6 6 6 6 Zinc finger, ZZ type FAD_binding_3 PF01494.14 CDO73093.1 - 3.2e-25 88.9 0.4 1.6e-24 86.6 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CDO73093.1 - 5.6e-07 29.4 2.8 1.5e-06 28.1 2.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CDO73093.1 - 2.5e-05 23.5 1.1 0.049 12.6 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 CDO73093.1 - 8e-05 21.6 4.3 0.00012 21.1 2.4 1.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CDO73093.1 - 0.00011 21.4 0.6 0.0002 20.5 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 CDO73093.1 - 0.00028 21.2 2.2 0.00056 20.2 1.6 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO73093.1 - 0.00065 18.2 3.2 0.00091 17.8 2.2 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 CDO73093.1 - 0.0008 18.3 4.0 0.0014 17.5 2.8 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 CDO73093.1 - 0.0038 15.9 1.3 0.0059 15.2 0.9 1.2 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.17 CDO73093.1 - 0.0089 14.9 2.3 0.012 14.4 1.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 CDO73093.1 - 0.014 14.2 0.0 0.027 13.2 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase FAD_oxidored PF12831.2 CDO73093.1 - 0.031 13.3 4.3 0.052 12.6 3.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CDO73093.1 - 0.036 13.8 3.7 0.23 11.2 0.5 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CDO73093.1 - 0.04 13.7 2.3 0.07 12.9 1.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CDO73093.1 - 0.053 12.4 1.2 0.077 11.8 0.4 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 CDO73093.1 - 0.096 12.3 1.3 0.18 11.4 0.9 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aph-1 PF06105.7 CDO73094.1 - 0.043 13.0 1.7 0.044 13.0 1.2 1.0 1 0 0 1 1 1 0 Aph-1 protein TMEM154 PF15102.1 CDO73094.1 - 1 9.0 3.3 1.1 8.9 2.3 1.1 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.1 CDO73094.1 - 1.4 9.0 6.8 1.8 8.6 4.7 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator V-SNARE_C PF12352.3 CDO73095.1 - 4.4e-16 58.6 0.9 4.4e-16 58.6 0.6 2.7 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Occludin_ELL PF07303.8 CDO73095.1 - 0.0041 17.8 0.3 0.085 13.5 0.2 2.7 2 1 1 3 3 3 1 Occludin homology domain Laminin_I PF06008.9 CDO73095.1 - 0.016 14.5 3.7 0.039 13.2 1.4 2.0 1 1 0 2 2 2 0 Laminin Domain I TBPIP PF07106.8 CDO73095.1 - 0.047 13.2 1.8 0.095 12.2 0.6 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 CDO73095.1 - 0.095 12.7 1.6 1.4 9.0 0.2 2.5 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.7 CDO73095.1 - 0.12 12.1 3.7 0.61 9.8 1.4 2.6 1 1 1 2 2 2 0 Laminin Domain II TipAS PF07739.8 CDO73095.1 - 0.14 12.4 1.2 0.41 10.9 0.1 2.0 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain Baculo_PEP_C PF04513.7 CDO73095.1 - 0.27 11.0 4.9 4.6 7.0 1.0 2.5 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 CDO73095.1 - 0.3 10.8 6.5 0.34 10.6 3.2 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein WXG100 PF06013.7 CDO73095.1 - 0.33 10.9 3.7 3.3 7.7 0.1 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG GrpE PF01025.14 CDO73095.1 - 0.68 9.4 3.6 1.4 8.3 2.5 1.6 1 1 0 1 1 1 0 GrpE Tropomyosin_1 PF12718.2 CDO73095.1 - 0.92 9.3 4.4 0.61 9.9 0.8 2.0 1 1 2 3 3 3 0 Tropomyosin like CorA PF01544.13 CDO73095.1 - 1.6 7.6 6.1 3.1 6.7 4.2 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein TatD_DNase PF01026.16 CDO73096.1 - 9.4e-22 77.4 0.0 1.8e-21 76.5 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 CDO73096.1 - 0.0019 17.8 0.5 0.079 12.5 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase Met_10 PF02475.11 CDO73097.1 - 4e-47 160.4 0.0 3.4e-28 98.6 0.0 2.2 1 1 1 2 2 2 2 Met-10+ like-protein Methyltransf_26 PF13659.1 CDO73097.1 - 1.6e-05 24.8 0.0 4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 CDO73097.1 - 0.00021 20.8 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_18 PF12847.2 CDO73097.1 - 0.0043 17.6 0.1 0.012 16.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CDO73097.1 - 0.007 15.0 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.9 CDO73097.1 - 0.031 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.5 CDO73097.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Mito_carr PF00153.22 CDO73098.1 - 5.4e-45 151.0 0.6 1.2e-17 63.4 0.0 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 CDO73098.1 - 1.2e-17 61.7 4.7 2e-05 23.5 0.1 6.0 7 0 0 7 7 7 3 EF hand EF-hand_7 PF13499.1 CDO73098.1 - 3.1e-17 62.4 1.5 2.2e-06 27.7 0.2 4.6 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CDO73098.1 - 1.2e-15 55.9 4.1 0.00016 21.2 0.1 5.4 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 CDO73098.1 - 1.2e-12 47.2 5.1 0.0014 18.1 0.0 5.3 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.1 CDO73098.1 - 6e-09 34.8 3.1 0.00019 20.6 0.1 4.1 4 0 0 4 4 4 2 EF hand Amidase PF01425.16 CDO73100.1 - 2.2e-93 313.5 0.0 3.4e-93 312.9 0.0 1.3 1 0 0 1 1 1 1 Amidase DUF953 PF06110.6 CDO73100.1 - 3.5e-18 65.1 0.1 7.7e-18 64.0 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) FR47 PF08445.5 CDO73101.1 - 2.8e-08 33.4 0.0 5.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CDO73101.1 - 4.5e-08 33.2 0.0 8.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CDO73101.1 - 3.2e-07 30.3 0.0 5.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO73101.1 - 2.2e-05 24.4 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CDO73101.1 - 0.0021 17.9 0.0 0.0055 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MoaC PF01967.16 CDO73102.1 - 1.2e-37 128.6 4.7 1.5e-16 60.2 0.3 3.3 2 1 1 3 3 3 3 MoaC family Mob_synth_C PF06463.8 CDO73102.1 - 8.3e-36 122.4 0.0 1.4e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 CDO73102.1 - 4.6e-05 23.6 0.1 0.025 14.7 0.0 2.4 1 1 1 2 2 2 2 Radical SAM superfamily NIPSNAP PF07978.8 CDO73104.1 - 5e-28 97.0 1.7 2.6e-22 78.7 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP TPR_1 PF00515.23 CDO73104.1 - 0.16 11.6 1.0 0.31 10.7 0.7 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MAD PF05557.8 CDO73105.1 - 0.033 12.2 12.8 0.05 11.6 8.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF1993 PF09351.5 CDO73105.1 - 0.19 11.6 2.5 0.3 10.9 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) PV-1 PF06637.6 CDO73105.1 - 4.3 5.8 16.9 6.3 5.2 11.7 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) WD40 PF00400.27 CDO73106.1 - 6.8e-76 247.6 23.7 7e-09 35.2 0.1 11.9 11 1 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 CDO73106.1 - 3.9e-37 127.0 0.0 6.1e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 CDO73106.1 - 3.6e-07 29.2 0.6 0.53 8.9 0.0 5.7 3 2 3 6 6 6 3 Nup133 N terminal like Met_synt_B12 PF02965.12 CDO73106.1 - 0.24 10.5 0.8 3.1 6.9 0.0 2.5 3 0 0 3 3 3 0 Vitamin B12 dependent methionine synthase, activation domain DUF89 PF01937.14 CDO73107.1 - 5e-109 364.3 0.0 6.3e-109 364.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Ribonuclease_T2 PF00445.13 CDO73108.1 - 8.5e-43 146.1 0.0 1.3e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Peptidase_C24 PF03510.9 CDO73108.1 - 0.0075 16.4 3.2 2.8 8.1 0.5 3.2 3 0 0 3 3 3 2 2C endopeptidase (C24) cysteine protease family Apo-CIII PF05778.7 CDO73108.1 - 0.21 10.9 2.3 0.27 10.6 0.1 2.1 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Aldedh PF00171.17 CDO73109.1 - 1.9e-111 372.6 0.0 2.6e-111 372.1 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CDO73109.1 - 0.0021 16.8 0.3 0.0067 15.1 0.2 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) zf-RING_2 PF13639.1 CDO73110.1 - 1.7e-12 46.9 7.0 1.7e-12 46.9 4.9 1.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CDO73110.1 - 8e-11 41.9 2.6 8e-11 41.9 1.8 1.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDO73110.1 - 1.3e-06 27.9 7.2 1.3e-06 27.9 5.0 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDO73110.1 - 2.5e-06 27.2 1.1 5.1e-06 26.2 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CDO73110.1 - 7.2e-06 25.9 4.7 2e-05 24.5 3.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO73110.1 - 7.9e-06 25.5 4.8 7.9e-06 25.5 3.3 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CDO73110.1 - 1.1e-05 25.0 3.0 1.1e-05 25.0 2.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 CDO73110.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.5 3 0 0 3 3 3 0 zinc-finger zf-TFIIB PF13453.1 CDO73110.1 - 0.26 10.4 3.0 5.1 6.3 0.0 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger FANCL_C PF11793.3 CDO73110.1 - 0.75 9.8 6.8 4 7.4 4.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF1272 PF06906.6 CDO73110.1 - 0.82 9.5 5.0 1.7 8.5 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_UBOX PF13445.1 CDO73110.1 - 1.3 8.7 5.8 2.5 7.8 2.3 2.5 1 1 1 2 2 2 0 RING-type zinc-finger DUF2358 PF10184.4 CDO73111.1 - 0.0008 19.3 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.2 CDO73111.1 - 0.0012 19.2 0.0 0.0036 17.6 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.7 CDO73111.1 - 0.014 14.9 0.0 0.093 12.3 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Lgl_C PF08596.5 CDO73112.1 - 1.7e-32 112.4 0.0 3.7e-32 111.2 0.0 1.6 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CDO73112.1 - 9.7e-07 28.4 0.0 0.0023 17.7 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ICL PF00463.16 CDO73113.1 - 1.5e-193 643.7 0.0 1.8e-193 643.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CDO73113.1 - 1.1e-10 41.1 0.0 2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Na_H_Exchanger PF00999.16 CDO73116.1 - 2.4e-61 207.3 44.7 3.2e-61 206.9 31.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1034 PF06280.7 CDO73117.1 - 0.016 15.5 2.9 0.68 10.3 2.0 2.2 1 1 0 1 1 1 0 Fn3-like domain (DUF1034) Macoilin PF09726.4 CDO73117.1 - 9 4.4 6.7 9.3 4.3 4.6 1.0 1 0 0 1 1 1 0 Transmembrane protein ECH PF00378.15 CDO73118.1 - 5.5e-51 173.0 0.0 6.9e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2431 PF10354.4 CDO73119.1 - 7.9e-17 61.7 0.0 1.7e-16 60.5 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) WD40 PF00400.27 CDO73120.1 - 5.7e-32 108.4 1.5 2.3e-10 39.9 0.2 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CDO73120.1 - 1.2e-10 41.0 0.0 2.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ATP-synt_E PF05680.7 CDO73121.1 - 2.5e-19 69.0 0.1 2.6e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain Caudo_TAP PF02413.12 CDO73121.1 - 0.024 14.8 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein Stathmin PF00836.14 CDO73121.1 - 0.25 10.9 2.8 0.31 10.6 2.0 1.3 1 1 0 1 1 1 0 Stathmin family DUF349 PF03993.7 CDO73121.1 - 2.6 8.2 7.3 4.3 7.5 5.1 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) INO80_Ies4 PF08193.6 CDO73122.1 - 1.4e-05 25.1 0.1 1.4e-05 25.1 0.1 2.6 3 0 0 3 3 3 1 INO80 complex subunit Ies4 BSP_II PF05432.6 CDO73122.1 - 0.012 14.9 4.8 0.021 14.1 3.3 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.1 CDO73122.1 - 0.032 14.5 5.8 0.032 14.5 4.0 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 CDO73122.1 - 0.045 13.9 10.8 0.086 13.0 7.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 CDO73122.1 - 0.24 10.8 5.8 0.38 10.2 4.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 CDO73122.1 - 0.42 8.4 3.6 0.52 8.1 2.5 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 CDO73122.1 - 0.54 9.9 1.7 0.95 9.1 1.2 1.3 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.4 CDO73122.1 - 1.7 7.2 13.0 0.3 9.7 6.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 CDO73122.1 - 5.9 6.4 7.7 11 5.5 5.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Dopey_N PF04118.9 CDO73123.1 - 3.9e-65 219.6 0.1 2.2e-64 217.1 0.0 2.2 3 0 0 3 3 3 1 Dopey, N-terminal EF-hand_6 PF13405.1 CDO73124.1 - 7.8e-10 37.8 0.1 0.0023 17.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CDO73124.1 - 4.3e-08 32.1 0.1 1.3e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CDO73124.1 - 2.7e-07 30.5 2.2 3.3e-07 30.3 0.5 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CDO73124.1 - 1.1e-06 27.5 0.2 3e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 CDO73124.1 - 0.00069 19.6 1.5 0.0012 18.7 0.1 2.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 CDO73124.1 - 0.011 15.2 0.3 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Usp PF00582.21 CDO73124.1 - 4.9 7.3 5.8 20 5.3 1.2 2.3 2 0 0 2 2 2 0 Universal stress protein family Peptidase_C48 PF02902.14 CDO73127.1 - 1.2e-14 54.4 0.1 2.4e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ABC2_membrane PF01061.19 CDO73129.1 - 1.6e-70 236.5 53.7 2.5e-38 131.3 16.5 2.8 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 CDO73129.1 - 8.8e-35 119.9 0.0 3.7e-16 59.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CDO73129.1 - 2.6e-22 78.4 0.0 7.2e-17 60.9 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter AAA_22 PF13401.1 CDO73129.1 - 1.2e-05 25.4 0.4 0.13 12.4 0.1 2.9 2 2 0 2 2 2 2 AAA domain cobW PF02492.14 CDO73129.1 - 1.9e-05 24.1 0.1 0.039 13.3 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC_trans_N PF14510.1 CDO73129.1 - 3.9e-05 23.6 0.1 0.00012 22.0 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CDO73129.1 - 5.5e-05 22.6 0.2 0.055 12.8 0.1 2.8 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CDO73129.1 - 0.00079 20.2 0.0 0.39 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CDO73129.1 - 0.00087 19.1 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CDO73129.1 - 0.0024 17.3 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.1 CDO73129.1 - 0.0028 17.1 0.1 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 CDO73129.1 - 0.0032 17.4 0.2 0.33 10.8 0.2 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CDO73129.1 - 0.0059 16.2 0.4 2.4 7.8 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC2_membrane_3 PF12698.2 CDO73129.1 - 0.0076 15.3 37.6 0.0058 15.7 11.4 2.6 2 0 0 2 2 2 1 ABC-2 family transporter protein SbcCD_C PF13558.1 CDO73129.1 - 0.013 15.4 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 CDO73129.1 - 0.018 14.2 0.0 0.085 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 CDO73129.1 - 0.022 14.9 0.0 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CDO73129.1 - 0.035 14.4 0.0 3.7 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CDO73129.1 - 0.057 12.8 0.1 1.2 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 CDO73129.1 - 0.072 12.8 1.7 5.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 CDO73129.1 - 0.096 12.6 0.4 4.1 7.3 0.2 3.0 2 2 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 CDO73129.1 - 0.13 11.5 0.0 2.4 7.3 0.0 2.6 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDO73129.1 - 0.19 11.6 0.0 32 4.3 0.0 2.6 2 1 0 3 3 2 0 AAA domain Prefoldin_2 PF01920.15 CDO73130.1 - 8.4e-19 67.2 11.6 1e-18 67.0 8.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 CDO73130.1 - 0.0017 18.2 3.0 0.0017 18.2 2.1 2.0 2 0 0 2 2 2 1 Tropomyosin like Seryl_tRNA_N PF02403.17 CDO73130.1 - 0.029 14.3 10.4 0.067 13.2 7.2 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FliD_C PF07195.7 CDO73130.1 - 0.039 13.2 4.4 0.074 12.3 0.9 2.0 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF3584 PF12128.3 CDO73130.1 - 0.05 10.9 6.9 0.068 10.4 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF793 PF05633.6 CDO73130.1 - 0.056 12.2 2.8 0.068 11.9 2.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF793) MIF4G_like_2 PF09090.6 CDO73130.1 - 0.14 11.3 2.0 0.16 11.1 1.4 1.2 1 0 0 1 1 1 0 MIF4G like CorA PF01544.13 CDO73130.1 - 0.19 10.7 3.9 2.2 7.2 0.7 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF3391 PF11871.3 CDO73130.1 - 0.22 11.7 2.9 0.41 10.8 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Lzipper-MIP1 PF14389.1 CDO73130.1 - 0.28 11.3 6.3 0.44 10.6 3.6 1.9 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DivIVA PF05103.8 CDO73130.1 - 0.3 11.1 10.2 0.89 9.6 0.7 2.1 2 0 0 2 2 2 0 DivIVA protein V_ATPase_I PF01496.14 CDO73130.1 - 0.41 8.4 6.0 0.46 8.2 4.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.4 CDO73130.1 - 0.61 9.8 12.1 2.9 7.7 6.8 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain Prefoldin PF02996.12 CDO73130.1 - 0.67 9.6 15.6 0.3 10.7 3.3 2.6 2 1 1 3 3 3 0 Prefoldin subunit DUF3450 PF11932.3 CDO73130.1 - 0.99 8.6 9.3 2.3 7.4 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 CDO73130.1 - 1 9.6 4.9 1.1 9.5 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PRP1_N PF06424.7 CDO73130.1 - 2.1 8.6 5.6 2.9 8.2 3.9 1.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal DivIC PF04977.10 CDO73130.1 - 2.2 7.8 13.7 0.6 9.6 2.6 2.3 2 0 0 2 2 2 0 Septum formation initiator NCA2 PF08637.5 CDO73130.1 - 2.4 7.0 7.1 1.8 7.3 0.6 2.0 1 1 1 2 2 2 0 ATP synthase regulation protein NCA2 AATF-Che1 PF13339.1 CDO73130.1 - 2.4 8.3 7.2 0.4 10.8 0.9 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor XhlA PF10779.4 CDO73130.1 - 2.7 7.9 13.2 0.15 11.9 3.1 2.1 2 0 0 2 2 2 0 Haemolysin XhlA TMF_DNA_bd PF12329.3 CDO73130.1 - 4.6 7.1 15.9 0.18 11.6 5.2 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CDO73130.1 - 5.1 6.6 13.4 9.4 5.7 9.3 1.4 1 1 0 1 1 1 0 IncA protein GrpE PF01025.14 CDO73130.1 - 5.6 6.4 8.8 1.5 8.3 3.7 1.7 1 1 0 2 2 2 0 GrpE Fzo_mitofusin PF04799.8 CDO73130.1 - 5.8 6.2 7.3 3.4 7.0 3.1 1.7 1 1 1 2 2 2 0 fzo-like conserved region DUF4407 PF14362.1 CDO73130.1 - 6.1 5.7 8.9 13 4.5 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 CDO73130.1 - 6.7 5.6 11.8 7.8 5.4 7.1 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 GTP_EFTU PF00009.22 CDO73131.1 - 8.1e-41 139.5 0.0 1.3e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CDO73131.1 - 2.9e-27 94.6 0.0 6.6e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CDO73131.1 - 3.2e-21 74.9 0.0 1.5e-20 72.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CDO73131.1 - 1.9e-09 37.4 0.1 4.7e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CDO73131.1 - 1.7e-05 24.7 0.1 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CDO73131.1 - 0.00043 20.7 0.1 0.00078 19.9 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 CDO73131.1 - 0.019 14.7 0.1 2.2 8.0 0.1 2.3 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.5 CDO73131.1 - 0.021 14.0 0.1 0.052 12.7 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TSCPD PF12637.2 CDO73131.1 - 0.053 13.4 0.1 6.5 6.7 0.0 2.5 2 0 0 2 2 2 0 TSCPD domain EFG_II PF14492.1 CDO73131.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II Calreticulin PF00262.13 CDO73132.1 - 1.2e-153 511.1 11.4 1.6e-153 510.7 7.9 1.2 1 0 0 1 1 1 1 Calreticulin family DSHCT PF08148.7 CDO73133.1 - 2.9e-62 209.0 1.4 3.6e-62 208.7 0.3 1.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 CDO73133.1 - 3.8e-22 78.5 0.3 9.9e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 CDO73133.1 - 4.3e-13 49.0 0.0 6.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 CDO73133.1 - 8.1e-06 25.6 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO73133.1 - 0.013 15.3 0.0 0.049 13.4 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ist1 PF03398.9 CDO73134.1 - 1.3e-07 31.1 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RasGEF PF00617.14 CDO73135.1 - 4.6e-36 124.3 0.2 7.1e-36 123.6 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CDO73135.1 - 1.2e-17 63.9 0.4 2.2e-17 63.0 0.3 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 CDO73135.1 - 5.1e-14 51.3 0.2 1.2e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CDO73135.1 - 2e-10 40.0 0.0 3.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CDO73135.1 - 5.9e-08 32.1 0.1 1.2e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ras PF00071.17 CDO73136.1 - 1.3e-56 190.4 0.2 1.5e-56 190.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO73136.1 - 4.6e-20 72.2 0.0 6.6e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO73136.1 - 3e-12 46.1 0.1 3.5e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO73136.1 - 4.1e-06 26.1 0.0 5e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDO73136.1 - 5.9e-06 25.8 0.0 1.2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDO73136.1 - 1.4e-05 25.0 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CDO73136.1 - 0.044 12.9 0.4 0.17 11.0 0.0 1.9 2 1 0 3 3 3 0 Protein of unknown function, DUF258 DUF385 PF04075.9 CDO73136.1 - 0.053 13.4 0.1 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF385) Septin PF00735.13 CDO73136.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.1 CDO73136.1 - 0.094 12.6 0.2 0.15 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.17 CDO73137.1 - 9.9e-15 53.9 0.0 6.5e-09 35.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO73137.1 - 4.1e-09 36.2 0.0 0.00023 21.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO73137.1 - 5.4e-09 35.7 0.0 4.3e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 CDO73139.1 - 5.9e-09 35.6 0.1 7.7e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDO73139.1 - 1.4e-06 28.2 0.0 1.7e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain polyprenyl_synt PF00348.12 CDO73141.1 - 3.5e-49 167.0 0.0 2.4e-45 154.4 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase RWP-RK PF02042.10 CDO73144.1 - 0.028 14.2 0.1 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 RWP-RK domain DUF837 PF05769.6 CDO73145.1 - 1.7e-08 34.2 0.8 1.8e-08 34.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF837) DUF677 PF05055.7 CDO73145.1 - 0.039 12.6 0.8 0.048 12.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF904 PF06005.7 CDO73145.1 - 0.042 14.1 6.8 0.11 12.8 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) PA26 PF04636.8 CDO73145.1 - 0.063 11.9 0.7 0.073 11.7 0.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HALZ PF02183.13 CDO73145.1 - 0.067 12.9 3.6 1.1 9.0 1.1 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 CDO73145.1 - 0.35 10.5 5.9 0.4 10.4 1.5 2.5 2 1 1 3 3 3 0 Sperm tail C-terminal domain DUF972 PF06156.8 CDO73145.1 - 0.74 10.1 6.0 0.56 10.5 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 CDO73145.1 - 1.2 9.1 6.1 2.3 8.2 1.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF2414 PF10309.4 CDO73146.1 - 3.1e-07 29.9 0.0 4.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 CDO73146.1 - 0.002 18.0 0.1 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain TPR_11 PF13414.1 CDO73147.1 - 9.5e-19 66.8 13.1 2.5e-15 55.8 4.3 4.7 4 2 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 CDO73147.1 - 1.1e-11 43.8 16.7 9.1e-05 21.9 1.6 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CDO73147.1 - 9.6e-10 37.6 22.0 0.00045 19.9 1.9 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CDO73147.1 - 6e-06 26.0 10.4 0.023 14.8 1.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO73147.1 - 0.0042 17.3 16.1 0.023 15.0 3.9 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDO73147.1 - 0.0043 17.7 7.2 0.0043 17.7 5.0 4.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO73147.1 - 0.0069 16.9 16.7 0.028 15.0 3.8 5.4 4 1 2 6 6 6 2 Tetratricopeptide repeat ChAPs PF09295.5 CDO73147.1 - 0.014 14.2 0.7 0.023 13.5 0.5 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.1 CDO73147.1 - 0.47 10.4 12.4 0.15 12.0 1.9 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2404 PF10296.4 CDO73150.1 - 6.4e-27 93.5 0.0 1.2e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 CDO73150.1 - 0.011 15.8 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 PH domain AAA_13 PF13166.1 CDO73152.1 - 9.9e-05 20.9 83.9 0.0041 15.6 11.2 4.1 1 1 3 4 4 4 3 AAA domain Myosin_tail_1 PF01576.14 CDO73152.1 - 0.00042 18.1 129.0 0.026 12.2 26.2 3.8 1 1 2 3 3 3 3 Myosin tail Tropomyosin_1 PF12718.2 CDO73152.1 - 0.00083 19.2 23.9 0.00083 19.2 16.6 8.2 1 1 6 7 7 6 3 Tropomyosin like Reo_sigmaC PF04582.7 CDO73152.1 - 0.0012 18.1 64.7 0.011 14.8 2.5 7.3 2 1 5 8 8 8 4 Reovirus sigma C capsid protein AAA_27 PF13514.1 CDO73152.1 - 0.0019 16.0 24.9 0.0019 16.0 17.3 2.7 1 1 1 2 2 2 1 AAA domain Spc7 PF08317.6 CDO73152.1 - 0.0031 16.2 10.8 0.0031 16.2 7.5 6.6 1 1 5 6 6 6 4 Spc7 kinetochore protein DUF869 PF05911.6 CDO73152.1 - 0.004 15.4 100.1 0.01 14.1 14.3 4.4 1 1 3 4 4 4 3 Plant protein of unknown function (DUF869) DUF4201 PF13870.1 CDO73152.1 - 0.0061 16.0 10.0 0.0061 16.0 6.9 8.3 1 1 6 7 7 7 1 Domain of unknown function (DUF4201) ATG16 PF08614.6 CDO73152.1 - 0.0088 15.8 129.5 0.5 10.1 12.5 8.6 1 1 5 6 6 6 3 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 CDO73152.1 - 0.019 14.7 1.5 0.019 14.7 1.0 8.6 4 2 6 11 11 11 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.15 CDO73152.1 - 0.045 12.8 130.0 0.058 12.4 37.0 7.4 2 1 5 7 7 7 0 Tropomyosin CENP-F_leu_zip PF10473.4 CDO73152.1 - 0.056 13.3 139.1 0.19 11.5 9.8 8.4 2 1 6 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 CDO73152.1 - 0.086 11.7 111.7 0.11 11.4 14.0 5.8 1 1 5 6 6 6 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CDO73152.1 - 0.28 10.7 153.0 2.3 7.8 9.9 7.9 1 1 5 7 7 7 0 IncA protein MscS_porin PF12795.2 CDO73152.1 - 0.66 9.2 143.0 0.061 12.6 24.7 6.0 3 1 2 6 6 6 0 Mechanosensitive ion channel porin domain Cast PF10174.4 CDO73152.1 - 2.1 6.3 131.4 0.12 10.4 9.4 4.1 1 1 3 4 4 4 0 RIM-binding protein of the cytomatrix active zone Bacillus_HBL PF05791.6 CDO73152.1 - 7 5.9 59.9 0.22 10.9 0.5 8.0 2 2 5 7 7 7 0 Bacillus haemolytic enterotoxin (HBL) WD40 PF00400.27 CDO73153.1 - 3.1e-55 182.1 23.2 1.3e-09 37.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CDO73153.1 - 0.00021 21.0 0.0 0.091 12.4 0.0 2.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A dsrm PF00035.20 CDO73154.1 - 1.2e-06 29.0 0.0 1.6e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.20 CDO73155.1 - 1.2e-07 32.1 0.1 1.4e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 CDO73155.1 - 0.042 14.1 0.1 0.062 13.5 0.1 1.4 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 UCH PF00443.24 CDO73156.1 - 4.8e-34 117.7 0.0 6.5e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CDO73156.1 - 7e-11 42.0 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CDO73156.1 - 0.00027 20.4 0.0 0.00054 19.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rsm22 PF09243.5 CDO73157.1 - 6.2e-40 136.9 0.0 6.2e-25 87.7 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Ribosomal_L1 PF00687.16 CDO73158.1 - 6.9e-19 68.0 0.0 9.8e-19 67.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family MRP-L28 PF09812.4 CDO73159.1 - 1.2e-11 44.6 5.9 2.9e-09 36.9 1.6 2.4 2 1 1 3 3 3 2 Mitochondrial ribosomal protein L28 PCI PF01399.22 CDO73160.1 - 5.3e-20 71.6 1.6 6.3e-20 71.4 0.2 1.8 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CDO73160.1 - 9.9e-12 44.8 0.2 2.3e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 CDO73160.1 - 0.074 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator PIP5K PF01504.13 CDO73161.1 - 5.8e-57 192.6 1.0 1.5e-45 155.3 0.2 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CDO73161.1 - 6e-26 91.1 0.0 9.1e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CDO73161.1 - 2.9e-17 62.3 11.5 2.9e-17 62.3 8.0 2.1 2 0 0 2 2 2 1 FYVE zinc finger LTV PF04180.9 CDO73162.1 - 3.6e-67 227.7 30.1 5.7e-64 217.1 7.1 3.9 1 1 1 2 2 2 2 Low temperature viability protein Bromodomain PF00439.20 CDO73163.1 - 6.7e-63 208.6 0.0 4e-22 77.9 0.1 3.8 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 CDO73163.1 - 4.2e-09 35.9 0.3 2.8e-05 23.4 0.0 3.3 1 1 0 2 2 2 1 Peptidase family M1 HEAT_2 PF13646.1 CDO73163.1 - 0.041 14.1 1.4 11 6.3 0.0 4.0 4 0 0 4 4 4 0 HEAT repeats Peptidase_MA_2 PF13485.1 CDO73163.1 - 0.079 13.0 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Peptidase MA superfamily Het-C PF07217.6 CDO73164.1 - 4e-209 695.7 0.0 4.3e-208 692.3 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cnd3 PF12719.2 CDO73164.1 - 0.043 12.8 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain TBCA PF02970.11 CDO73167.1 - 2.2e-18 66.1 5.1 2.5e-18 65.9 3.3 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A DUF641 PF04859.7 CDO73167.1 - 0.24 11.1 4.6 0.24 11.1 1.0 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HrpB7 PF09486.5 CDO73167.1 - 0.25 11.2 5.3 0.36 10.7 3.6 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.3 CDO73167.1 - 0.34 10.7 6.1 0.9 9.3 1.1 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HLH PF00010.21 CDO73168.1 - 1.7e-08 34.0 3.3 1.7e-08 34.0 2.3 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.14 CDO73168.1 - 0.28 11.6 5.4 2.1 8.8 2.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Spt5_N PF11942.3 CDO73168.1 - 7.6 7.2 11.0 33 5.1 7.6 2.1 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal 5TM-5TMR_LYT PF07694.7 CDO73169.1 - 0.11 11.8 12.0 0.068 12.4 5.5 2.0 2 0 0 2 2 2 0 5TMR of 5TMR-LYT Baculo_11_kDa PF06143.6 CDO73169.1 - 0.23 10.8 2.9 0.17 11.2 0.7 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family HLH PF00010.21 CDO73170.1 - 1e-10 41.1 1.4 4.2e-10 39.1 0.9 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1192 PF06698.6 CDO73170.1 - 0.12 12.2 0.4 0.12 12.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Atg14 PF10186.4 CDO73170.1 - 0.12 11.2 4.1 0.18 10.6 2.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 CDO73170.1 - 0.14 11.6 7.0 0.062 12.7 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 CDO73170.1 - 0.2 11.5 2.7 0.53 10.1 1.9 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FTA4 PF13093.1 CDO73170.1 - 0.73 9.2 7.2 0.095 12.1 2.1 1.7 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 IncA PF04156.9 CDO73170.1 - 4.3 6.8 6.6 14 5.1 4.6 1.8 1 1 0 1 1 1 0 IncA protein CIMR PF00878.13 CDO73171.1 - 1.6e-12 47.4 0.0 6.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 CDO73171.1 - 2e-08 33.5 0.0 3.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 CDO73171.1 - 5e-07 29.2 0.3 6.5e-06 25.5 0.2 2.2 1 1 0 1 1 1 1 Autophagy-related protein 27 Complex1_49kDa PF00346.14 CDO73172.1 - 1.3e-114 381.8 0.0 1.8e-114 381.3 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit SoxZ PF08770.6 CDO73172.1 - 0.041 13.3 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ NiFeSe_Hases PF00374.14 CDO73172.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase NIF3 PF01784.13 CDO73173.1 - 1.5e-56 191.6 0.0 1.8e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Glutaredoxin PF00462.19 CDO73174.1 - 6.3e-20 70.9 0.0 8.9e-20 70.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CDO73174.1 - 9.4e-05 22.1 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 CDO73174.1 - 0.0041 16.6 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CDO73174.1 - 0.011 15.8 0.3 0.027 14.6 0.2 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 CDO73174.1 - 0.012 15.9 0.1 0.016 15.4 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF723 PF05265.8 CDO73174.1 - 0.027 14.2 0.6 2.3 8.0 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF723) Thioredoxin_4 PF13462.1 CDO73174.1 - 0.065 13.2 0.2 1.5 8.8 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin GST_N_3 PF13417.1 CDO73174.1 - 0.081 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CSTF_C PF14304.1 CDO73175.1 - 4.6e-10 38.6 0.1 4.6e-10 38.6 0.1 1.7 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal Metal_resist PF13801.1 CDO73175.1 - 0.037 14.0 1.0 0.037 14.0 0.7 2.2 1 1 1 2 2 2 0 Heavy-metal resistance Adaptin_N PF01602.15 CDO73176.1 - 1.7e-98 330.2 10.4 2.5e-98 329.6 7.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CDO73176.1 - 7.1e-67 223.0 0.0 2e-66 221.5 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CDO73176.1 - 1.3e-58 196.6 0.0 4.6e-58 194.8 0.0 2.0 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CDO73176.1 - 5.4e-13 49.0 2.7 0.0004 20.5 0.0 5.0 4 2 1 5 5 5 3 HEAT repeats HEAT PF02985.17 CDO73176.1 - 1.9e-06 27.4 0.5 0.087 12.9 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 CDO73176.1 - 8.2e-05 22.5 7.5 0.57 10.0 0.3 4.9 2 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CDO73176.1 - 0.0035 17.7 0.6 12 6.5 0.0 5.3 5 2 3 8 8 8 1 HEAT-like repeat Gemini_V1 PF01524.12 CDO73176.1 - 0.0052 16.7 0.1 0.21 11.5 0.0 2.8 2 0 0 2 2 2 1 Geminivirus V1 protein ParcG PF10274.4 CDO73176.1 - 0.026 14.4 3.6 0.5 10.2 0.0 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein Transp_cyt_pur PF02133.10 CDO73177.1 - 1.3e-22 80.0 19.8 9.1e-13 47.5 3.2 2.2 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_transf_22 PF03901.12 CDO73179.1 - 1.6e-90 304.0 16.2 2e-90 303.8 11.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PAH PF02671.16 CDO73182.1 - 4.2e-40 135.1 6.2 5.3e-16 57.9 1.2 3.4 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CDO73182.1 - 1.9e-35 120.6 0.0 4e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor TMEM154 PF15102.1 CDO73182.1 - 0.014 15.0 0.0 0.043 13.5 0.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family PWI PF01480.12 CDO73182.1 - 0.03 14.4 0.7 0.052 13.6 0.0 1.8 2 0 0 2 2 2 0 PWI domain RPW8 PF05659.6 CDO73182.1 - 0.43 10.1 0.1 1.3 8.5 0.0 1.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SieB PF14163.1 CDO73182.1 - 0.98 8.9 0.0 2.6 7.6 0.0 1.6 1 0 0 1 1 1 0 Superinfection exclusion protein B K_trans PF02705.11 CDO73182.1 - 4.4 5.5 0.0 6.5 4.9 0.0 1.1 1 0 0 1 1 1 0 K+ potassium transporter SH3_1 PF00018.23 CDO73184.1 - 3.4e-12 45.5 0.1 5.9e-12 44.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CDO73184.1 - 1.6e-10 40.3 0.0 2.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CDO73184.1 - 3e-10 39.5 0.0 5.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CDO73184.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain PgaD PF13994.1 CDO73184.1 - 0.083 12.3 3.2 0.067 12.6 1.2 1.5 1 1 0 1 1 1 0 PgaD-like protein zf-C3HC4_2 PF13923.1 CDO73185.1 - 2.1e-08 34.0 11.1 3.3e-08 33.4 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO73185.1 - 3e-08 33.1 9.1 5.1e-08 32.4 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO73185.1 - 2e-06 27.4 9.9 3.4e-06 26.7 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CDO73185.1 - 5.3e-06 25.9 6.2 8.5e-06 25.3 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDO73185.1 - 1.2e-05 25.0 10.6 2e-05 24.3 7.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CDO73185.1 - 3e-05 23.6 6.8 5.2e-05 22.8 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CDO73185.1 - 0.00019 21.0 5.7 0.00034 20.2 2.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 CDO73185.1 - 0.0003 20.2 9.5 0.00053 19.4 6.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CDO73185.1 - 0.035 13.6 5.1 0.062 12.8 3.5 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 CDO73185.1 - 0.1 12.7 3.0 0.21 11.7 2.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 CDO73185.1 - 0.37 10.6 2.8 0.9 9.3 2.0 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein NpwBP PF12622.2 CDO73186.1 - 1.6e-16 60.5 7.9 1.6e-16 60.5 5.5 7.4 6 1 0 6 6 6 1 mRNA biogenesis factor Wbp11 PF09429.5 CDO73186.1 - 4.6e-15 55.3 6.4 9.4e-15 54.3 4.4 1.5 1 0 0 1 1 1 1 WW domain binding protein 11 IncA PF04156.9 CDO73186.1 - 0.24 10.9 6.9 0.36 10.4 4.8 1.2 1 0 0 1 1 1 0 IncA protein Latarcin PF10279.4 CDO73186.1 - 0.37 10.9 2.9 0.67 10.1 2.0 1.4 1 0 0 1 1 1 0 Latarcin precursor PBP_sp32 PF07222.7 CDO73186.1 - 3.3 6.8 7.3 5 6.2 5.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 F-box-like PF12937.2 CDO73188.1 - 0.024 14.3 0.1 0.057 13.1 0.1 1.7 1 0 0 1 1 1 0 F-box-like Aspzincin_M35 PF14521.1 CDO73189.1 - 2.6e-42 144.8 5.2 2.9e-42 144.6 3.6 1.0 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 CDO73189.1 - 0.016 14.6 1.3 0.11 11.8 0.1 2.0 1 1 1 2 2 2 0 Putative peptidase family Peptidase_M35 PF02102.10 CDO73189.1 - 0.76 8.3 9.9 1.1 7.8 6.8 1.4 1 1 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 CDO73190.1 - 9.7e-45 152.6 2.3 1.8e-44 151.8 1.6 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.10 CDO73190.1 - 3.1e-09 35.9 10.6 1.6e-08 33.6 7.3 2.0 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.1 CDO73190.1 - 0.00063 19.2 1.2 0.46 9.8 0.8 2.1 1 1 0 1 1 1 1 Putative peptidase family Metallophos PF00149.23 CDO73191.1 - 3.8e-11 42.7 1.0 3.2e-09 36.4 0.7 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDO73191.1 - 2.2e-05 24.3 0.0 4.9e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF619 PF04768.8 CDO73192.1 - 1.3e-36 125.5 0.0 4.8e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF619) Mito_carr PF00153.22 CDO73194.1 - 2.3e-56 187.4 8.3 4.2e-21 74.4 0.1 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Fasciclin PF02469.17 CDO73195.1 - 3.8e-62 207.9 0.0 1.2e-15 57.6 0.0 5.4 5 1 0 5 5 5 5 Fasciclin domain Rav1p_C PF12234.3 CDO73196.1 - 5.1e-181 603.0 0.0 1.2e-180 601.8 0.0 1.5 1 1 0 1 1 1 1 RAVE protein 1 C terminal GDI PF00996.13 CDO73197.1 - 2.3e-210 698.4 0.0 2.7e-210 698.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor PK PF00224.16 CDO73198.1 - 6.7e-162 537.9 1.1 8.9e-162 537.5 0.8 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CDO73198.1 - 7.5e-33 112.5 0.5 3.7e-32 110.3 0.0 2.4 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CDO73198.1 - 2.2e-05 23.4 0.9 8e-05 21.6 0.2 1.9 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 CDO73198.1 - 8e-05 21.6 0.8 0.0014 17.5 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Toprim_3 PF13362.1 CDO73198.1 - 0.18 12.0 1.8 2.4 8.4 0.0 3.3 4 0 0 4 4 4 0 Toprim domain Gly_transf_sug PF04488.10 CDO73199.1 - 3.8e-05 24.0 0.0 8.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 CDO73199.1 - 0.099 11.7 0.2 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein LMWPc PF01451.16 CDO73200.1 - 8.2e-28 97.4 0.0 1.3e-14 54.7 0.0 2.1 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase Aldedh PF00171.17 CDO73201.1 - 2.1e-122 408.7 0.1 2.5e-122 408.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SH3BGR PF04908.10 CDO73202.1 - 8.6e-05 22.4 0.3 0.064 13.2 0.2 3.4 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Seipin PF06775.9 CDO73203.1 - 1.6e-13 50.6 0.0 5.5e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) LCCL PF03815.14 CDO73206.1 - 1.5e-14 53.7 0.0 2.5e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 LCCL domain DUF2076 PF09849.4 CDO73208.1 - 0.13 12.2 8.7 0.19 11.7 5.4 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TRAPPC-Trs85 PF12739.2 CDO73209.1 - 3.4e-22 78.6 0.0 1.3e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.6 CDO73209.1 - 0.17 9.1 0.0 0.3 8.3 0.0 1.3 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit HTH_8 PF02954.14 CDO73209.1 - 0.22 11.0 0.5 0.44 10.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Mpv17_PMP22 PF04117.7 CDO73210.1 - 5.3e-10 38.7 1.7 8e-10 38.2 1.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF4416 PF14385.1 CDO73210.1 - 0.019 14.6 0.1 0.023 14.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) DUF599 PF04654.7 CDO73210.1 - 0.045 12.9 0.1 0.054 12.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF599 Mito_carr PF00153.22 CDO73211.1 - 7.6e-33 112.0 5.6 1.1e-15 57.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_4 PF12799.2 CDO73212.1 - 4.2e-06 26.2 5.2 0.00016 21.1 0.2 2.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 CDO73212.1 - 0.0057 16.3 0.2 0.02 14.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 CDO73212.1 - 0.0083 15.8 3.4 0.055 13.2 1.5 2.4 2 0 0 2 2 2 1 Leucine rich repeat Fez1 PF06818.10 CDO73213.1 - 0.003 17.6 18.2 0.003 17.6 12.6 5.6 1 1 3 5 5 5 1 Fez1 CENP-F_leu_zip PF10473.4 CDO73213.1 - 0.0077 16.1 17.6 0.0077 16.1 12.2 7.8 2 1 7 9 9 9 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 CDO73213.1 - 0.017 14.5 123.5 0.1 12.0 6.5 6.5 1 1 2 4 4 4 0 Intermediate filament protein DUF3268 PF11672.3 CDO73213.1 - 4.7 7.3 7.5 16 5.5 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3268) Reo_sigmaC PF04582.7 CDO73213.1 - 9 5.3 66.4 0.084 12.0 1.4 5.6 1 1 4 6 6 6 0 Reovirus sigma C capsid protein Ras PF00071.17 CDO73214.1 - 1.3e-38 131.9 0.0 1.6e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO73214.1 - 2.4e-10 40.9 0.0 3.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CDO73214.1 - 0.019 14.4 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Arf PF00025.16 CDO73214.1 - 0.093 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Exo_endo_phos PF03372.18 CDO73215.1 - 1.2e-22 81.0 0.0 1.6e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGEF PF00621.15 CDO73216.1 - 2.3e-17 63.4 0.0 3.6e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Fungal_trans PF04082.13 CDO73218.1 - 6.7e-12 44.8 0.0 1.1e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CDO73218.1 - 0.13 12.2 1.8 0.33 10.9 1.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH PF00642.19 CDO73219.1 - 2e-14 52.8 15.7 4e-05 23.1 0.4 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 CDO73219.1 - 0.00011 21.9 4.7 0.00052 19.8 3.3 2.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_2 PF14608.1 CDO73219.1 - 0.0081 16.1 20.4 0.062 13.3 0.2 4.4 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHC_3 PF13917.1 CDO73219.1 - 0.012 15.3 2.0 0.023 14.4 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Peptidase_M16_C PF05193.16 CDO73221.1 - 4.2e-19 68.9 0.0 5.3e-12 45.7 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CDO73221.1 - 3.5e-11 43.0 0.1 2.8e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF1949 PF09186.6 CDO73221.1 - 0.0043 16.6 0.0 0.045 13.3 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1949) NUFIP1 PF10453.4 CDO73222.1 - 7e-17 60.6 1.1 7e-17 60.6 0.7 1.8 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Clathrin_lg_ch PF01086.12 CDO73222.1 - 1.6 8.5 5.6 1.2 8.9 0.2 2.2 2 0 0 2 2 2 0 Clathrin light chain KH_1 PF00013.24 CDO73223.1 - 2.6e-40 135.8 10.3 1.2e-15 56.9 0.2 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CDO73223.1 - 9.7e-30 101.6 10.5 3e-10 39.5 1.1 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CDO73223.1 - 9.1e-11 41.2 0.0 0.012 15.1 0.0 3.5 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 CDO73223.1 - 1.4e-10 40.5 3.7 0.0096 15.4 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CDO73223.1 - 0.00044 19.9 4.2 0.13 12.1 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 CDO73223.1 - 0.21 11.0 0.9 8.4 5.8 0.1 2.7 3 0 0 3 3 3 0 dUTPase Ribosomal_L13 PF00572.13 CDO73224.1 - 6.8e-27 94.0 0.0 1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 PP-binding PF00550.20 CDO73225.1 - 4.5e-14 52.4 0.7 6.2e-14 52.0 0.5 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CDO73225.1 - 2.9e-06 27.2 0.4 4.1e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 CDO73225.1 - 0.017 15.1 0.2 0.024 14.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SGL PF08450.7 CDO73226.1 - 9.2e-55 185.6 0.0 1.2e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PQQ PF01011.16 CDO73226.1 - 0.0059 16.0 1.2 0.46 10.1 0.1 3.3 3 0 0 3 3 3 1 PQQ enzyme repeat Ribosomal_L17 PF01196.14 CDO73227.1 - 1e-32 112.5 0.0 2.6e-31 108.0 0.0 2.5 1 1 0 1 1 1 1 Ribosomal protein L17 ADH_N PF08240.7 CDO73229.1 - 2.8e-31 107.4 0.3 6e-31 106.4 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO73229.1 - 8.1e-18 64.2 0.0 8.7e-14 51.1 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CDO73229.1 - 3.2e-05 23.1 0.0 5.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 CDO73229.1 - 0.00016 21.2 0.0 0.00039 20.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain TrkA_N PF02254.13 CDO73229.1 - 0.0077 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_11 PF08241.7 CDO73229.1 - 0.0092 16.4 0.0 0.043 14.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO73229.1 - 0.033 14.7 0.0 0.08 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FANCL_C PF11793.3 CDO73229.1 - 0.037 13.9 0.4 0.078 12.9 0.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain ADH_N_assoc PF13823.1 CDO73229.1 - 0.079 12.6 0.3 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Intg_mem_TP0381 PF09529.5 CDO73231.1 - 0.035 13.3 2.5 0.5 9.5 2.0 1.9 1 1 1 2 2 2 0 Integral membrane protein (intg_mem_TP0381) CDP-OH_P_tran_2 PF08009.6 CDO73231.1 - 0.065 12.9 1.4 0.29 10.9 1.0 2.1 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 DUF2749 PF10907.3 CDO73231.1 - 0.099 12.5 0.1 0.6 10.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) MerC PF03203.9 CDO73231.1 - 0.93 9.8 6.4 11 6.4 0.5 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein RNase_T PF00929.19 CDO73232.1 - 2.9e-23 82.9 0.0 7.2e-23 81.6 0.0 1.6 2 0 0 2 2 2 1 Exonuclease E1_DerP2_DerF2 PF02221.10 CDO73232.1 - 3.9e-22 78.9 0.3 5.7e-22 78.3 0.2 1.3 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 CDO73232.1 - 0.00044 20.2 0.0 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 ML-like domain Cellulase PF00150.13 CDO73233.1 - 7.5e-24 84.4 1.6 9.4e-24 84.0 1.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 CDO73233.1 - 9.2e-07 29.2 0.0 3.2e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 CDO73233.1 - 6.3e-05 22.2 0.3 0.0021 17.2 0.0 3.0 2 2 0 2 2 2 1 Beta-galactosidase Prim-Pol PF09250.6 CDO73233.1 - 0.018 15.0 0.1 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Glyco_hydro_10 PF00331.15 CDO73233.1 - 0.044 12.8 0.0 0.079 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Glyco_hydro_2_C PF02836.12 CDO73233.1 - 0.055 12.3 0.0 0.22 10.3 0.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain LRR_8 PF13855.1 CDO73235.1 - 0.24 11.1 2.5 43 3.9 0.0 3.3 2 1 1 3 3 3 0 Leucine rich repeat DPBB_1 PF03330.13 CDO73236.1 - 1.6e-08 34.3 0.0 1.9e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CDO73236.1 - 0.076 12.6 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 Barwin family JAB PF01398.16 CDO73237.1 - 2e-10 40.3 0.0 3.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease T2SK PF03934.8 CDO73240.1 - 0.063 12.4 2.2 0.15 11.1 1.5 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein K Fungal_trans PF04082.13 CDO73241.1 - 7.9e-18 64.2 0.2 1.4e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AATF-Che1 PF13339.1 CDO73242.1 - 2.6e-12 47.0 0.1 2.6e-12 47.0 0.1 2.4 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 CDO73242.1 - 0.053 13.6 0.1 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal CobT PF06213.7 CDO73242.1 - 0.4 9.7 16.8 0.49 9.4 10.9 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 CDO73242.1 - 1.5 6.6 18.1 1.9 6.3 12.5 1.1 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.6 CDO73242.1 - 2.4 7.9 6.3 4.1 7.2 4.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.7 CDO73242.1 - 5.7 6.1 16.1 7.7 5.6 11.2 1.2 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.2 CDO73242.1 - 9.3 3.7 6.9 11 3.5 4.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ras PF00071.17 CDO73243.1 - 5.5e-36 123.3 0.0 1.3e-34 118.9 0.0 2.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CDO73243.1 - 3.6e-09 37.1 0.0 8.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CDO73243.1 - 0.19 11.6 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Clathrin PF00637.15 CDO73244.1 - 8.5e-207 677.0 36.4 9.7e-33 112.7 0.6 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 CDO73244.1 - 4.6e-33 111.2 1.8 0.00029 20.9 0.0 7.7 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 CDO73244.1 - 9.4e-30 102.3 0.4 3.3e-29 100.5 0.1 2.2 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.5 CDO73244.1 - 6.2e-11 41.0 0.1 1.8e-10 39.6 0.1 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 CDO73244.1 - 1.4e-05 24.0 6.0 0.44 9.2 0.0 4.8 5 0 0 5 5 5 3 Coatomer WD associated region TPR_14 PF13428.1 CDO73244.1 - 0.027 15.0 14.8 13 6.7 0.1 9.3 9 1 1 10 10 10 0 Tetratricopeptide repeat Nucleoporin_N PF08801.6 CDO73244.1 - 0.11 11.1 0.0 0.31 9.7 0.0 1.6 2 0 0 2 2 2 0 Nup133 N terminal like TPR_1 PF00515.23 CDO73244.1 - 0.39 10.4 8.0 33 4.2 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CDO73244.1 - 1.2 9.1 8.4 59 3.9 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDO73244.1 - 2.8 7.9 10.3 17 5.5 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Fungal_trans PF04082.13 CDO73245.1 - 1.9e-20 72.8 1.1 3.9e-20 71.8 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CDO73245.1 - 1.8e-05 24.5 9.2 3.1e-05 23.7 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syntaxin-6_N PF09177.6 CDO73245.1 - 0.06 13.7 0.1 2.6 8.5 0.0 2.8 3 0 0 3 3 3 0 Syntaxin 6, N-terminal PDCD2_C PF04194.8 CDO73246.1 - 5e-34 117.2 0.0 5e-34 117.2 0.0 2.2 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain FlpD PF02662.11 CDO73246.1 - 0.13 11.9 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit MAGE_N PF12440.3 CDO73246.1 - 1.5 9.1 10.7 3.7 7.8 7.2 1.9 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal zf-RING_3 PF14369.1 CDO73246.1 - 3 7.8 7.2 11 6.1 0.4 2.6 2 0 0 2 2 2 0 zinc-finger PH PF00169.24 CDO73247.1 - 8.6e-06 25.9 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 PH domain CAF-1_p150 PF11600.3 CDO73247.1 - 0.025 13.9 34.9 0.038 13.3 24.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CheF-arch PF04283.7 CDO73247.1 - 0.045 12.9 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Chemotaxis signal transduction system protein F from archaea SPX PF03105.14 CDO73247.1 - 0.07 12.9 4.5 0.074 12.8 3.2 1.1 1 0 0 1 1 1 0 SPX domain Asp-B-Hydro_N PF05279.6 CDO73247.1 - 6.5 6.5 17.2 10 5.9 12.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region ATP-synt_ab PF00006.20 CDO73248.1 - 2.4e-70 236.4 0.0 3.2e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CDO73248.1 - 2.8e-22 79.3 0.1 7.5e-22 77.9 0.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CDO73248.1 - 3.3e-18 65.6 0.8 8.2e-18 64.3 0.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CDO73248.1 - 0.00032 20.5 0.7 0.00094 19.0 0.5 1.8 1 0 0 1 1 1 1 HAS barrel domain Ribosomal_L21p PF00829.16 CDO73249.1 - 4.8e-15 55.4 0.1 6.3e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein SPOR PF05036.8 CDO73249.1 - 0.12 12.5 0.1 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Sporulation related domain FF PF01846.14 CDO73250.1 - 2.5e-23 81.7 7.5 6.5e-08 32.4 0.0 6.3 6 1 1 7 7 7 4 FF domain PX PF00787.19 CDO73250.1 - 5.1e-21 74.5 0.7 1.9e-20 72.7 0.0 2.4 3 0 0 3 3 3 1 PX domain WW PF00397.21 CDO73250.1 - 6.4e-16 57.8 15.2 2.3e-08 33.7 1.8 2.8 2 0 0 2 2 2 2 WW domain Vps5 PF09325.5 CDO73250.1 - 1.6e-05 24.3 20.6 0.00092 18.5 2.3 2.9 3 0 0 3 3 3 2 Vps5 C terminal like FliD_N PF02465.13 CDO73250.1 - 0.067 13.5 6.1 0.038 14.3 1.0 2.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus PQ-loop PF04193.9 CDO73251.1 - 2e-14 52.8 3.0 4.9e-14 51.6 2.1 1.7 1 0 0 1 1 1 1 PQ loop repeat UDPGT PF00201.13 CDO73252.1 - 1.1e-18 67.0 0.1 1.5e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CDO73252.1 - 6.3e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF2408 PF10303.4 CDO73253.1 - 3.3e-60 202.0 1.1 1.1e-33 116.1 0.5 5.2 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.1 CDO73253.1 - 0.07 13.4 5.1 0.78 10.0 0.2 3.8 4 0 0 4 4 4 0 Snapin/Pallidin MscS_porin PF12795.2 CDO73253.1 - 0.18 11.0 9.6 1.5 8.0 3.2 2.5 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.2 CDO73254.1 - 3.8e-45 153.2 36.3 4.9e-45 152.8 25.2 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CDO73254.1 - 6.8e-13 48.2 34.7 6.7e-07 28.6 14.2 2.9 1 1 1 2 2 2 2 Tropomyosin Myosin_tail_1 PF01576.14 CDO73254.1 - 0.00035 18.4 33.6 0.00051 17.9 23.3 1.2 1 0 0 1 1 1 1 Myosin tail Cast PF10174.4 CDO73254.1 - 0.00072 17.7 28.5 0.0011 17.1 19.8 1.2 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone CENP-F_leu_zip PF10473.4 CDO73254.1 - 0.002 18.0 36.7 0.035 13.9 11.4 3.0 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 CDO73254.1 - 0.0021 17.4 24.9 0.054 12.7 8.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) WEMBL PF05701.6 CDO73254.1 - 0.0026 16.3 32.1 0.0044 15.5 22.2 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light BicD PF09730.4 CDO73254.1 - 0.0029 16.0 22.5 0.0035 15.7 15.6 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF484 PF04340.7 CDO73254.1 - 0.0029 17.0 8.2 0.0029 17.0 5.7 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF484 ERM PF00769.14 CDO73254.1 - 0.0042 16.6 33.1 0.0042 16.6 23.0 2.0 1 1 1 2 2 2 1 Ezrin/radixin/moesin family AAA_27 PF13514.1 CDO73254.1 - 0.0046 14.7 27.2 0.006 14.3 18.9 1.1 1 0 0 1 1 1 1 AAA domain ADIP PF11559.3 CDO73254.1 - 0.0056 16.5 32.2 0.11 12.3 5.1 3.4 1 1 3 4 4 4 2 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 CDO73254.1 - 0.0058 16.3 35.1 0.022 14.4 9.5 2.7 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein DUF4559 PF15112.1 CDO73254.1 - 0.0087 15.2 10.8 0.012 14.7 7.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) IncA PF04156.9 CDO73254.1 - 0.0088 15.6 32.8 0.029 13.9 22.8 1.8 1 1 0 1 1 1 1 IncA protein EzrA PF06160.7 CDO73254.1 - 0.032 12.4 26.5 0.024 12.8 5.1 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TMF_DNA_bd PF12329.3 CDO73254.1 - 0.035 13.8 37.9 0.037 13.8 7.7 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding FliJ PF02050.11 CDO73254.1 - 0.041 13.9 31.9 0.17 11.9 9.4 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein GAS PF13851.1 CDO73254.1 - 0.082 12.0 32.8 0.21 10.7 11.8 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.8 CDO73254.1 - 0.083 12.8 28.8 3 7.7 11.8 2.9 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF4200 PF13863.1 CDO73254.1 - 0.09 12.7 36.6 0.16 11.9 8.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Uds1 PF15456.1 CDO73254.1 - 0.091 12.7 26.8 0.23 11.4 5.6 2.5 1 1 1 2 2 2 0 Up-regulated During Septation Laminin_II PF06009.7 CDO73254.1 - 0.11 12.2 19.8 0.054 13.2 2.7 2.5 1 1 1 2 2 2 0 Laminin Domain II IFT57 PF10498.4 CDO73254.1 - 0.17 10.5 25.3 0.63 8.7 8.0 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 APG6 PF04111.7 CDO73254.1 - 0.18 10.8 36.3 0.3 10.1 15.2 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 CDO73254.1 - 0.2 11.4 31.6 0.11 12.2 8.5 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Fmp27_WPPW PF10359.4 CDO73254.1 - 0.2 10.0 25.2 0.047 12.1 6.9 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF702 PF05142.7 CDO73254.1 - 0.21 11.7 6.5 1.2 9.2 4.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF702) HR1 PF02185.11 CDO73254.1 - 0.23 11.2 27.9 0.19 11.4 3.9 4.1 1 1 2 4 4 4 0 Hr1 repeat HisKA_3 PF07730.8 CDO73254.1 - 0.31 11.4 13.1 5.4 7.4 2.3 4.1 2 1 1 3 3 3 0 Histidine kinase PspA_IM30 PF04012.7 CDO73254.1 - 0.32 10.3 33.2 1.6 8.0 6.8 2.2 1 1 1 2 2 2 0 PspA/IM30 family Reo_sigmaC PF04582.7 CDO73254.1 - 0.38 9.8 4.7 3.9 6.5 0.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2422 PF10337.4 CDO73254.1 - 0.39 9.4 8.4 0.48 9.1 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) FliD_C PF07195.7 CDO73254.1 - 0.44 9.7 15.9 4.9 6.3 11.0 2.2 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Nup54 PF13874.1 CDO73254.1 - 0.48 10.0 22.5 0.17 11.5 7.1 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 AAA_13 PF13166.1 CDO73254.1 - 0.57 8.5 25.0 1.7 7.0 17.4 1.6 1 1 0 1 1 1 0 AAA domain IZUMO PF15005.1 CDO73254.1 - 0.61 10.1 8.2 1.5 8.8 5.0 1.9 1 1 0 2 2 2 0 Izumo sperm-egg fusion NPV_P10 PF05531.7 CDO73254.1 - 0.63 10.3 9.2 3.9 7.8 0.4 3.4 2 1 2 4 4 3 0 Nucleopolyhedrovirus P10 protein SurA_N PF09312.6 CDO73254.1 - 0.64 9.8 10.4 0.13 12.1 3.8 2.1 1 1 1 2 2 2 0 SurA N-terminal domain DUF1140 PF06600.6 CDO73254.1 - 0.72 10.0 7.5 0.43 10.7 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1140) CALCOCO1 PF07888.6 CDO73254.1 - 0.75 8.0 24.6 0.17 10.1 5.2 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.6 CDO73254.1 - 0.76 9.5 29.5 0.78 9.5 18.6 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 CDO73254.1 - 0.83 6.9 31.5 1.8 5.8 21.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) WXG100 PF06013.7 CDO73254.1 - 0.93 9.5 18.1 3.5 7.7 3.1 4.1 3 1 1 4 4 4 0 Proteins of 100 residues with WXG GLE1 PF07817.8 CDO73254.1 - 1 8.2 9.7 0.053 12.4 1.7 2.1 1 1 1 2 2 2 0 GLE1-like protein DUF883 PF05957.8 CDO73254.1 - 1.1 9.6 18.5 2.7 8.4 0.7 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) YdfA_immunity PF12127.3 CDO73254.1 - 1.1 8.0 7.6 1.1 8.1 4.7 1.3 1 1 0 1 1 1 0 SigmaW regulon antibacterial BLOC1_2 PF10046.4 CDO73254.1 - 1.3 9.1 22.3 3.3 7.8 4.9 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 THOC7 PF05615.8 CDO73254.1 - 1.4 9.2 29.9 0.37 11.0 5.8 3.0 1 1 2 3 3 3 0 Tho complex subunit 7 Flagellin_C PF00700.16 CDO73254.1 - 1.4 9.1 6.4 0.59 10.3 0.4 2.8 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region Seryl_tRNA_N PF02403.17 CDO73254.1 - 1.4 8.9 30.7 1.3 9.0 13.1 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 CDO73254.1 - 1.6 7.2 29.8 2.7 6.5 7.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein BRE1 PF08647.6 CDO73254.1 - 1.9 8.4 30.0 1.7 8.6 6.5 3.1 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Atg14 PF10186.4 CDO73254.1 - 2.1 7.2 27.5 55 2.5 19.0 2.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4164 PF13747.1 CDO73254.1 - 2.4 8.3 31.0 4.5 7.4 8.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF4201 PF13870.1 CDO73254.1 - 2.4 7.5 29.0 7.6 5.9 1.4 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF812 PF05667.6 CDO73254.1 - 2.6 6.4 27.6 9.6 4.5 19.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Lectin_N PF03954.9 CDO73254.1 - 3 7.2 11.0 35 3.7 0.7 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.5 CDO73254.1 - 3.1 7.9 17.5 7 6.7 3.7 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_I PF06008.9 CDO73254.1 - 3.7 6.7 28.0 20 4.3 9.8 2.3 1 1 1 2 2 2 0 Laminin Domain I DUF4094 PF13334.1 CDO73254.1 - 3.7 8.0 13.0 3.7 7.9 0.9 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Prefoldin_2 PF01920.15 CDO73254.1 - 4 7.2 33.7 0.65 9.7 3.6 4.2 1 1 3 4 4 4 0 Prefoldin subunit DUF3287 PF11690.3 CDO73254.1 - 4.1 7.5 11.6 0.29 11.2 1.6 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) DUF3391 PF11871.3 CDO73254.1 - 4.2 7.5 18.5 15 5.8 1.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) Striatin PF08232.7 CDO73254.1 - 5 7.4 28.2 0.52 10.6 12.7 2.1 1 1 1 2 2 2 0 Striatin family DinB_2 PF12867.2 CDO73254.1 - 6 7.2 7.6 2.3 8.5 0.2 2.7 1 1 1 2 2 2 0 DinB superfamily DUF948 PF06103.6 CDO73254.1 - 8.2 6.3 9.8 9.4 6.1 0.2 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Rootletin PF15035.1 CDO73254.1 - 8.3 6.3 29.0 3.2 7.7 16.5 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion COG2 PF06148.6 CDO73254.1 - 8.5 6.2 22.2 2.3 8.0 1.8 3.1 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2229 PF09989.4 CDO73254.1 - 8.9 5.7 11.3 6.7 6.1 1.7 2.2 1 1 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Mvb12 PF09452.5 CDO73254.1 - 9.1 6.5 7.6 17 5.6 1.9 2.4 2 1 0 2 2 2 0 ESCRT-I subunit Mvb12 Tropomyosin_1 PF12718.2 CDO73255.1 - 4e-24 85.1 25.6 2.4e-21 76.1 10.8 2.0 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 CDO73255.1 - 2.4e-11 43.2 25.6 5.7e-10 38.6 17.8 2.0 1 1 0 1 1 1 1 Tropomyosin DUF4200 PF13863.1 CDO73255.1 - 0.00013 21.9 26.3 0.002 18.0 5.5 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) GAS PF13851.1 CDO73255.1 - 0.00024 20.3 22.0 0.00033 19.9 15.3 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ADIP PF11559.3 CDO73255.1 - 0.0004 20.3 20.6 0.049 13.5 7.0 2.1 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 CDO73255.1 - 0.00051 19.9 23.2 0.013 15.3 16.8 2.0 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 CDO73255.1 - 0.0009 18.8 20.2 0.0011 18.5 14.0 1.1 1 0 0 1 1 1 1 IncA protein AAA_27 PF13514.1 CDO73255.1 - 0.0012 16.6 18.1 0.0018 16.0 12.5 1.2 1 0 0 1 1 1 1 AAA domain ERM PF00769.14 CDO73255.1 - 0.0022 17.5 28.0 0.0027 17.2 19.4 1.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.4 CDO73255.1 - 0.0033 17.4 21.1 0.0088 16.0 14.7 1.6 1 1 0 1 1 1 1 JNK_SAPK-associated protein-1 bZIP_1 PF00170.16 CDO73255.1 - 0.0051 16.7 17.1 0.0057 16.5 2.4 2.9 1 1 1 2 2 2 1 bZIP transcription factor Laminin_II PF06009.7 CDO73255.1 - 0.0059 16.3 9.8 0.0096 15.6 6.0 1.7 1 1 1 2 2 2 1 Laminin Domain II Prefoldin_2 PF01920.15 CDO73255.1 - 0.0059 16.3 22.0 0.032 13.9 5.4 3.0 1 1 1 2 2 2 1 Prefoldin subunit APG6 PF04111.7 CDO73255.1 - 0.006 15.6 19.5 0.007 15.4 13.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 CDO73255.1 - 0.017 14.9 23.3 0.069 12.9 7.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cast PF10174.4 CDO73255.1 - 0.019 13.0 24.1 0.056 11.4 16.7 1.7 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone K-box PF01486.12 CDO73255.1 - 0.024 14.4 16.0 10 6.0 10.6 3.3 1 1 0 1 1 1 0 K-box region ATG16 PF08614.6 CDO73255.1 - 0.024 14.4 22.1 0.064 13.0 4.8 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Clr5 PF14420.1 CDO73255.1 - 0.033 14.0 2.0 0.076 12.9 1.4 1.6 1 0 0 1 1 1 0 Clr5 domain Laminin_I PF06008.9 CDO73255.1 - 0.041 13.2 14.4 0.058 12.7 9.9 1.3 1 0 0 1 1 1 0 Laminin Domain I Spc7 PF08317.6 CDO73255.1 - 0.063 11.9 17.1 0.072 11.7 11.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FliD_C PF07195.7 CDO73255.1 - 0.07 12.4 8.4 0.11 11.7 1.8 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Reo_sigmaC PF04582.7 CDO73255.1 - 0.079 12.1 0.3 0.084 12.0 0.2 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CDO73255.1 - 0.08 11.3 12.1 0.091 11.2 8.4 1.2 1 0 0 1 1 1 0 AAA domain Filament PF00038.16 CDO73255.1 - 0.11 11.9 19.2 0.035 13.5 10.5 1.7 1 1 1 2 2 2 0 Intermediate filament protein DUF730 PF05325.6 CDO73255.1 - 0.14 12.0 11.3 1.3 8.8 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF730) WXG100 PF06013.7 CDO73255.1 - 0.15 12.1 7.0 1.4 8.9 0.9 3.0 1 1 1 2 2 2 0 Proteins of 100 residues with WXG FlxA PF14282.1 CDO73255.1 - 0.15 12.0 9.5 0.18 11.7 6.1 1.5 1 1 0 1 1 1 0 FlxA-like protein EzrA PF06160.7 CDO73255.1 - 0.17 10.0 17.5 0.012 13.8 4.5 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA BLOC1_2 PF10046.4 CDO73255.1 - 0.17 12.0 12.3 0.94 9.6 1.3 2.5 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 CDO73255.1 - 0.18 11.5 24.5 2.6 7.8 4.8 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 CDO73255.1 - 0.18 11.6 2.9 2.2 8.1 0.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.6 CDO73255.1 - 0.19 10.2 15.4 0.21 10.0 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Ax_dynein_light PF10211.4 CDO73255.1 - 0.24 11.2 21.0 0.63 9.8 5.2 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain HOOK PF05622.7 CDO73255.1 - 0.26 9.0 20.6 0.33 8.6 14.2 1.1 1 0 0 1 1 1 0 HOOK protein RICH PF05062.7 CDO73255.1 - 0.28 11.3 8.5 2.1 8.5 0.7 2.6 2 2 0 2 2 2 0 RICH domain IFT57 PF10498.4 CDO73255.1 - 0.41 9.3 13.3 0.55 8.9 9.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PEARLI-4 PF05278.7 CDO73255.1 - 0.42 9.9 13.1 0.53 9.6 9.1 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) KLRAQ PF10205.4 CDO73255.1 - 0.44 10.6 10.8 0.13 12.3 4.1 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein WEMBL PF05701.6 CDO73255.1 - 0.59 8.5 23.7 0.3 9.5 8.8 1.8 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 CDO73255.1 - 0.68 7.1 21.7 0.77 7.0 15.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Herpes_UL6 PF01763.11 CDO73255.1 - 0.7 7.9 9.1 0.68 8.0 1.3 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF3450 PF11932.3 CDO73255.1 - 0.7 9.1 16.8 26 3.9 11.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Spc24 PF08286.6 CDO73255.1 - 0.82 9.3 15.3 2 8.1 2.9 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HlyD_2 PF12700.2 CDO73255.1 - 0.84 8.7 8.9 1.1 8.3 6.2 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Sipho_Gp157 PF05565.6 CDO73255.1 - 0.87 9.1 18.1 1.7 8.1 1.4 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 PilJ PF13675.1 CDO73255.1 - 0.89 9.8 10.7 1.1 9.6 2.5 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fib_alpha PF08702.5 CDO73255.1 - 0.89 9.6 9.1 3 7.9 1.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 CDO73255.1 - 0.9 8.4 21.9 6.9 5.5 15.2 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2968 PF11180.3 CDO73255.1 - 0.92 8.8 18.0 0.34 10.2 5.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF1664 PF07889.7 CDO73255.1 - 1.2 8.9 7.3 1.3 8.7 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4446 PF14584.1 CDO73255.1 - 1.3 8.8 12.0 1.2 8.9 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) bZIP_Maf PF03131.12 CDO73255.1 - 1.4 9.2 16.6 1 9.6 3.2 2.7 1 1 1 2 2 2 0 bZIP Maf transcription factor AATF-Che1 PF13339.1 CDO73255.1 - 1.4 9.1 12.0 1.5 9.0 7.6 1.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Cob_adeno_trans PF01923.13 CDO73255.1 - 1.4 8.6 8.5 0.66 9.7 2.4 1.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase HisKA_3 PF07730.8 CDO73255.1 - 1.4 9.3 10.0 4.9 7.5 2.5 2.9 1 1 1 2 2 2 0 Histidine kinase KIP1 PF07765.7 CDO73255.1 - 1.5 8.7 8.0 0.26 11.1 0.3 2.7 1 1 2 3 3 3 0 KIP1-like protein FH2 PF02181.18 CDO73255.1 - 1.6 7.5 11.4 0.25 10.1 3.8 1.8 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF4337 PF14235.1 CDO73255.1 - 1.7 8.5 21.7 2 8.2 4.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF1640 PF07798.6 CDO73255.1 - 1.7 8.6 12.1 2.1 8.3 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) LXG PF04740.7 CDO73255.1 - 1.7 8.3 9.8 0.36 10.5 2.7 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF4140 PF13600.1 CDO73255.1 - 1.8 9.0 19.0 1.1 9.6 3.4 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) LMBR1 PF04791.11 CDO73255.1 - 2 6.8 5.7 2.2 6.7 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Microtub_assoc PF07989.6 CDO73255.1 - 2.1 8.2 11.8 0.094 12.5 2.3 2.4 1 1 1 2 2 2 0 Microtubule associated Syntaxin_2 PF14523.1 CDO73255.1 - 2.1 8.4 9.1 2.8 8.0 6.0 1.3 1 1 0 1 1 1 0 Syntaxin-like protein CCDC155 PF14662.1 CDO73255.1 - 2.1 7.8 21.2 3.1 7.3 14.7 1.3 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Hormone_1 PF00103.15 CDO73255.1 - 2.2 7.5 5.5 1.7 7.8 0.7 1.9 1 1 1 2 2 2 0 Somatotropin hormone family Vps5 PF09325.5 CDO73255.1 - 2.2 7.4 16.8 0.075 12.2 4.6 2.1 1 1 1 2 2 2 0 Vps5 C terminal like DUF3994 PF13159.1 CDO73255.1 - 2.2 8.5 9.5 2.4 8.4 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3994) Nsp1_C PF05064.8 CDO73255.1 - 2.2 7.9 11.6 0.5 10.0 2.4 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF4407 PF14362.1 CDO73255.1 - 2.3 7.1 15.4 8.5 5.2 10.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sec8_exocyst PF04048.9 CDO73255.1 - 2.4 7.8 9.4 2.1 7.9 1.0 2.6 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Adeno_PIX PF03955.9 CDO73255.1 - 2.4 8.7 7.0 3.2 8.3 1.3 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) GrpE PF01025.14 CDO73255.1 - 2.4 7.6 24.3 1.5 8.3 3.9 2.9 1 1 2 3 3 3 0 GrpE GBP_C PF02841.9 CDO73255.1 - 2.5 7.2 16.9 4.6 6.3 11.7 1.4 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain SPX PF03105.14 CDO73255.1 - 2.8 7.6 10.4 3.6 7.3 7.2 1.2 1 0 0 1 1 1 0 SPX domain DUF4201 PF13870.1 CDO73255.1 - 2.8 7.3 22.0 5.5 6.3 10.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HlyD PF00529.15 CDO73255.1 - 3.4 6.8 13.8 5 6.3 9.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein AKNA PF12443.3 CDO73255.1 - 3.5 7.7 13.3 0.63 10.0 3.0 2.5 1 1 1 2 2 2 0 AT-hook-containing transcription factor MAD PF05557.8 CDO73255.1 - 3.6 5.5 21.4 4.4 5.2 14.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein HAUS5 PF14817.1 CDO73255.1 - 3.8 5.9 17.2 4.2 5.8 11.9 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Uds1 PF15456.1 CDO73255.1 - 3.9 7.4 19.3 0.48 10.4 8.6 2.0 1 1 1 2 2 2 0 Up-regulated During Septation Transposase_22 PF02994.9 CDO73255.1 - 4 5.8 15.3 15 3.9 10.6 1.7 1 1 0 1 1 1 0 L1 transposable element Prefoldin PF02996.12 CDO73255.1 - 4.6 6.9 15.2 16 5.1 4.3 3.0 1 1 2 3 3 3 0 Prefoldin subunit DUF342 PF03961.8 CDO73255.1 - 4.6 5.5 15.7 1.4 7.2 7.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TMCO5 PF14992.1 CDO73255.1 - 4.7 6.2 17.5 5.9 5.9 12.1 1.1 1 0 0 1 1 1 0 TMCO5 family Fzo_mitofusin PF04799.8 CDO73255.1 - 5.1 6.4 7.2 5.4 6.3 0.5 2.1 1 1 1 2 2 2 0 fzo-like conserved region Rootletin PF15035.1 CDO73255.1 - 5.6 6.9 21.7 39 4.1 15.0 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF848 PF05852.6 CDO73255.1 - 6.1 6.6 14.6 0.89 9.3 3.2 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TMPIT PF07851.8 CDO73255.1 - 6.8 5.6 7.7 8.5 5.3 5.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 CDO73255.1 - 6.9 4.3 11.9 8.1 4.1 8.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kinetocho_Slk19 PF12709.2 CDO73255.1 - 9.1 6.4 18.2 28 4.8 2.7 3.2 1 1 1 2 2 2 0 Central kinetochore-associated SelR PF01641.13 CDO73256.1 - 1.3e-51 173.5 0.1 1.5e-51 173.2 0.1 1.0 1 0 0 1 1 1 1 SelR domain GFA PF04828.9 CDO73256.1 - 0.0062 16.4 0.5 0.066 13.1 0.0 2.2 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF678 PF05077.7 CDO73256.1 - 0.033 14.1 0.0 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Ribosomal_L37e PF01907.14 CDO73256.1 - 0.058 13.2 2.2 0.59 9.9 0.4 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e zf-Mss51 PF13824.1 CDO73256.1 - 0.069 13.0 6.4 0.23 11.3 0.1 3.3 2 1 2 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.1 CDO73256.1 - 0.079 12.1 1.3 7.1 5.9 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 CDO73256.1 - 0.093 12.5 2.7 0.82 9.5 1.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon Yippee-Mis18 PF03226.9 CDO73256.1 - 0.24 11.4 0.9 3.5 7.7 0.6 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_2 PF13240.1 CDO73256.1 - 0.25 10.8 2.1 1.3 8.6 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RRN7 PF11781.3 CDO73256.1 - 0.31 10.5 2.4 4.4 6.8 0.5 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 CDO73256.1 - 2.5 7.5 5.9 13 5.2 0.3 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding Pkinase PF00069.20 CDO73257.1 - 1.8e-74 250.1 0.0 2.2e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73257.1 - 1.9e-32 112.3 0.0 7.7e-32 110.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CDO73257.1 - 0.02 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CDO73257.1 - 0.04 12.8 0.0 0.17 10.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like zf-RanBP PF00641.13 CDO73258.1 - 5.5e-12 44.5 11.4 2.6e-06 26.4 1.6 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 CDO73258.1 - 0.016 14.7 2.7 3.5 7.2 0.1 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DZR PF12773.2 CDO73258.1 - 3.3 7.5 7.2 7 6.5 5.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon NADH-u_ox-rdase PF10785.4 CDO73259.1 - 7.4e-33 112.6 0.1 9.8e-33 112.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 CDO73259.1 - 4.5e-16 58.3 0.0 6.9e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF4349 PF14257.1 CDO73260.1 - 0.016 14.4 0.1 0.038 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1192 PF06698.6 CDO73260.1 - 0.069 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Cortex-I_coil PF09304.5 CDO73260.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil bZIP_2 PF07716.10 CDO73260.1 - 0.35 10.7 0.1 0.35 10.7 0.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DnaJ PF00226.26 CDO73261.1 - 3.6e-14 52.2 1.9 8.3e-14 51.0 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain DDE_3 PF13358.1 CDO73261.1 - 2.3e-12 46.9 0.0 2.3e-12 46.9 0.0 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease SH3_1 PF00018.23 CDO73262.1 - 8.4e-18 63.4 2.7 1.1e-08 34.3 0.1 3.2 2 1 0 2 2 2 2 SH3 domain SAM_2 PF07647.12 CDO73262.1 - 3.9e-14 52.2 0.0 7.3e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 CDO73262.1 - 3.5e-13 48.8 2.2 7.4e-07 28.6 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CDO73262.1 - 2.1e-12 46.3 0.5 2.5e-09 36.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SAM_1 PF00536.25 CDO73262.1 - 5.9e-12 45.5 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 CDO73262.1 - 1.3e-10 41.6 0.0 2.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.6 CDO73262.1 - 0.01 16.0 2.5 1.6 9.0 0.3 2.8 2 0 0 2 2 2 0 Bacterial SH3 domain Chromo PF00385.19 CDO73264.1 - 5.3e-12 45.2 0.5 5.3e-12 45.2 0.3 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DnaJ PF00226.26 CDO73265.1 - 8e-21 73.5 0.6 1.6e-20 72.5 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain ThiS PF02597.15 CDO73265.1 - 0.063 13.7 2.0 1.5 9.3 0.0 3.2 2 2 1 3 3 3 0 ThiS family DUF2756 PF10956.3 CDO73265.1 - 0.21 11.8 1.7 0.42 10.8 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) DUF4407 PF14362.1 CDO73265.1 - 1.2 8.0 15.7 0.11 11.4 7.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Bac_small_YrzI PF09501.5 CDO73265.1 - 1.8 8.5 3.9 2.6 8.0 0.3 2.4 1 1 1 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) OHCU_decarbox PF09349.5 CDO73266.1 - 4.4e-31 108.3 0.0 6.2e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 OHCU decarboxylase CTP_transf_2 PF01467.21 CDO73267.1 - 0.0029 17.6 0.0 0.0045 17.0 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase zf-H2C2_2 PF13465.1 CDO73268.1 - 1.3e-19 69.4 24.9 1e-06 28.7 0.5 6.3 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.21 CDO73268.1 - 1.3e-18 66.1 20.5 0.00041 20.5 0.6 7.1 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO73268.1 - 4.4e-09 36.0 23.0 0.007 16.6 0.4 7.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CDO73268.1 - 3.9e-08 32.9 10.7 0.061 13.2 0.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CDO73268.1 - 0.019 15.1 8.9 0.047 13.8 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CDO73268.1 - 0.049 13.8 18.3 0.06 13.5 0.5 5.0 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CDO73268.1 - 0.057 13.5 11.5 0.61 10.2 3.0 4.4 3 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) Peptidase_M20 PF01546.23 CDO73269.1 - 3.9e-21 75.4 0.1 6.6e-21 74.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CDO73269.1 - 1.3e-13 50.6 0.0 5e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain M20_dimer PF07687.9 CDO73270.1 - 4e-10 39.4 0.1 7.3e-10 38.5 0.1 1.5 1 1 0 1 1 1 1 Peptidase dimerisation domain Herpes_UL6 PF01763.11 CDO73271.1 - 0.023 12.8 0.4 0.028 12.6 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Frankia_peptide PF14407.1 CDO73271.1 - 0.057 13.1 1.0 0.086 12.6 0.7 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Muted PF14942.1 CDO73271.1 - 0.085 12.7 6.3 0.11 12.3 4.4 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Desmo_N PF06771.6 CDO73271.1 - 0.091 12.6 0.2 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus ExbD PF02472.11 CDO73271.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF972 PF06156.8 CDO73271.1 - 1.8 8.9 5.5 2.3 8.6 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF914 PF06027.7 CDO73272.1 - 1.9e-105 352.4 9.5 2.6e-105 352.0 6.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) PsbX PF06596.6 CDO73272.1 - 0.31 10.7 3.2 1.2 8.8 0.1 2.9 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) DUF4131 PF13567.1 CDO73272.1 - 4.6 6.6 15.8 0.76 9.1 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) RRM_1 PF00076.17 CDO73273.1 - 2.1e-26 91.3 0.9 1.1e-14 53.7 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO73273.1 - 2.4e-21 75.4 0.0 4.1e-08 33.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO73273.1 - 2.2e-13 49.8 0.0 6.4e-05 22.7 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med3 PF11593.3 CDO73273.1 - 4.9 6.2 11.2 6.8 5.8 7.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Amidase PF01425.16 CDO73274.1 - 4.5e-68 230.1 0.0 3.7e-46 157.8 0.0 2.9 1 1 2 3 3 3 2 Amidase Fis1_TPR_C PF14853.1 CDO73275.1 - 2.7e-23 81.5 0.4 4.5e-23 80.8 0.3 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CDO73275.1 - 1.1e-12 47.0 0.0 1.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 CDO73275.1 - 0.00017 21.2 0.4 0.00042 20.0 0.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDO73275.1 - 0.015 15.9 0.6 0.033 14.8 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 CDO73275.1 - 0.02 15.0 0.2 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CDO73275.1 - 0.023 14.3 1.1 0.051 13.2 0.7 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 CDO73275.1 - 0.032 14.5 0.2 0.068 13.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDO73275.1 - 0.049 14.1 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 CDO73275.1 - 0.077 12.6 0.1 0.16 11.5 0.1 1.7 1 0 0 1 1 1 0 TPR repeat TPR_10 PF13374.1 CDO73275.1 - 0.21 11.5 0.5 0.21 11.5 0.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M50B PF13398.1 CDO73276.1 - 3e-43 147.5 16.9 3.9e-43 147.1 11.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Histone PF00125.19 CDO73277.1 - 1.6e-26 92.2 0.0 2e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CDO73277.1 - 1.7e-06 27.9 0.0 2.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_60s PF00428.14 CDO73278.1 - 3.5e-28 97.8 10.8 4.4e-28 97.5 7.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein MSP1_C PF07462.6 CDO73278.1 - 0.034 12.5 0.5 0.044 12.1 0.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3138 PF11336.3 CDO73278.1 - 0.072 11.2 0.7 0.077 11.1 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_S19 PF00203.16 CDO73279.1 - 7.5e-35 118.4 0.2 1.2e-34 117.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 CDO73279.1 - 0.0028 17.5 0.0 0.0034 17.2 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH RhoGAP PF00620.22 CDO73280.1 - 9.5e-36 122.6 0.1 1.7e-35 121.8 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 CDO73280.1 - 1.8e-28 98.3 39.0 4e-11 42.8 0.6 4.6 4 0 0 4 4 4 4 LIM domain Peptidase_M20 PF01546.23 CDO73281.1 - 4.9e-28 97.9 0.0 7.9e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CDO73281.1 - 2.4e-11 43.3 0.0 8.4e-11 41.5 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CDO73281.1 - 2.6e-05 24.0 0.0 5.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 Ribonucleas_3_3 PF14622.1 CDO73282.1 - 7.6e-10 38.8 0.0 1.8e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 CDO73282.1 - 5.2e-07 30.1 0.0 1.3e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 CDO73282.1 - 8e-05 23.0 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain RhoGAP PF00620.22 CDO73283.1 - 4.6e-10 39.3 0.1 1.2e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.16 CDO73283.1 - 1.6e-07 30.9 0.0 3.4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.18 CDO73283.1 - 0.00024 21.2 0.3 0.0099 16.0 0.0 3.1 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Zn_clus PF00172.13 CDO73284.1 - 1.1e-09 37.9 10.3 2.4e-09 36.9 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CDO73284.1 - 1.7e-07 30.4 0.6 1.7e-07 30.4 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain V-ATPase_G PF03179.10 CDO73285.1 - 5.4e-32 110.2 20.4 6.2e-32 110.0 14.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 CDO73285.1 - 0.0051 16.6 12.9 0.0051 16.6 8.9 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) S_layer_C PF05124.7 CDO73285.1 - 0.23 11.0 4.9 0.26 10.9 3.4 1.0 1 0 0 1 1 1 0 S-layer like family, C-terminal region Nop25 PF09805.4 CDO73285.1 - 0.28 11.2 11.7 0.36 10.8 8.1 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Muted PF14942.1 CDO73285.1 - 1.5 8.6 13.8 5.4 6.8 9.0 2.1 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Colicin-DNase PF12639.2 CDO73285.1 - 2.1 8.6 5.1 4.8 7.4 3.5 1.8 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin DUF2956 PF11169.3 CDO73285.1 - 5.1 7.1 11.8 7.6 6.5 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Seryl_tRNA_N PF02403.17 CDO73285.1 - 6.2 6.8 13.8 31 4.6 9.6 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rotamase_2 PF13145.1 CDO73285.1 - 8 7.1 13.4 1.7 9.2 0.2 2.2 1 1 1 2 2 2 0 PPIC-type PPIASE domain Symplekin_C PF12295.3 CDO73286.1 - 3.1e-56 190.2 0.2 5.6e-56 189.3 0.1 1.5 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 CDO73286.1 - 4.4e-50 170.3 0.1 9.3e-50 169.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) RNA_pol_Rpc4 PF05132.9 CDO73287.1 - 2.5e-27 95.4 0.1 2.5e-27 95.4 0.1 3.5 2 1 0 2 2 2 1 RNA polymerase III RPC4 HET PF06985.6 CDO73289.1 - 9.8e-20 71.1 3.5 8e-18 64.9 2.4 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mito_carr PF00153.22 CDO73290.1 - 1.5e-51 172.0 2.1 1.6e-24 85.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rick_17kDa_Anti PF05433.10 CDO73290.1 - 0.61 9.8 9.2 0.8 9.4 2.8 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain TFIID_30kDa PF03540.8 CDO73291.1 - 6.5e-27 93.1 0.0 9.1e-27 92.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 CDO73291.1 - 0.0013 19.1 0.3 0.0085 16.5 0.1 2.0 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Bromo_TP PF07524.8 CDO73291.1 - 0.04 13.6 0.0 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated Ribosomal_60s PF00428.14 CDO73291.1 - 0.042 14.2 0.0 0.042 14.2 0.0 2.2 2 2 0 2 2 2 0 60s Acidic ribosomal protein DUF3235 PF11574.3 CDO73291.1 - 0.047 13.9 0.4 0.047 13.9 0.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3235) Birna_VP4 PF01768.11 CDO73291.1 - 0.15 11.0 0.3 0.2 10.6 0.2 1.2 1 0 0 1 1 1 0 Birnavirus VP4 protein DUF2360 PF10152.4 CDO73291.1 - 8.2 6.7 8.1 3.2 8.0 3.6 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) GFO_IDH_MocA PF01408.17 CDO73292.1 - 7.1e-21 74.9 0.1 1.1e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zf-CCCH PF00642.19 CDO73293.1 - 0.37 10.5 3.8 0.76 9.5 2.6 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 CDO73294.1 - 3.3e-60 203.4 0.0 4e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73294.1 - 1.2e-32 113.0 0.0 1.5e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO73294.1 - 0.014 15.1 0.1 0.048 13.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CDO73294.1 - 0.03 13.3 0.1 0.08 12.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CDO73294.1 - 0.11 11.4 0.0 0.59 9.0 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Med3 PF11593.3 CDO73295.1 - 0.00045 19.5 2.1 0.00064 19.0 1.4 1.4 1 1 0 1 1 1 1 Mediator complex subunit 3 fungal Pkinase PF00069.20 CDO73295.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain ParA PF10609.4 CDO73296.1 - 1e-37 127.8 0.0 2.1e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CDO73296.1 - 6.5e-14 51.7 0.0 9.9e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CDO73296.1 - 2e-05 23.8 1.5 0.0029 16.6 0.1 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 CDO73296.1 - 0.00035 20.0 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 CDO73296.1 - 0.001 19.0 0.0 0.0034 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CDO73296.1 - 0.015 14.4 0.1 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 YhjQ PF06564.7 CDO73296.1 - 0.026 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 YhjQ protein YjeF_N PF03853.10 CDO73296.1 - 0.057 13.0 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus Fer4_NifH PF00142.13 CDO73296.1 - 0.057 12.5 0.0 0.87 8.7 0.0 2.4 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirE PF05272.6 CDO73296.1 - 0.091 12.2 0.1 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_26 PF13500.1 CDO73296.1 - 0.093 12.3 0.0 0.7 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain MipZ PF09140.6 CDO73296.1 - 0.15 11.1 0.1 0.73 8.8 0.0 1.9 1 1 0 1 1 1 0 ATPase MipZ AAA_29 PF13555.1 CDO73296.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CDO73296.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain WD40 PF00400.27 CDO73297.1 - 6.8e-23 79.6 5.3 1.4e-09 37.4 0.0 6.0 5 1 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CDO73297.1 - 9.7e-05 21.2 0.0 0.071 11.8 0.1 2.2 2 0 0 2 2 2 2 Nup133 N terminal like SCA7 PF08313.7 CDO73298.1 - 9.1e-30 102.0 0.2 9.1e-30 102.0 0.1 2.1 2 0 0 2 2 2 1 SCA7, zinc-binding domain YqzE PF14038.1 CDO73298.1 - 3 7.6 6.3 9.6 6.0 4.4 1.8 1 0 0 1 1 1 0 YqzE-like protein hDGE_amylase PF14701.1 CDO73299.1 - 4e-155 516.8 0.0 5.2e-155 516.4 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CDO73299.1 - 2.9e-116 388.2 0.0 4.3e-116 387.6 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CDO73299.1 - 1.1e-77 260.7 0.0 1.7e-77 260.1 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 CDO73299.1 - 3.8e-19 68.3 0.0 7.4e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 CDO73299.1 - 0.012 15.0 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase, catalytic domain Glyco_hydro_100 PF12899.2 CDO73299.1 - 0.2 10.0 0.0 0.37 9.1 0.0 1.3 1 0 0 1 1 1 0 Alkaline and neutral invertase Uricase PF01014.13 CDO73301.1 - 7.2e-58 194.5 0.0 2e-29 102.4 0.1 2.2 2 0 0 2 2 2 2 Uricase zf-CCCH PF00642.19 CDO73302.1 - 1.4e-11 43.7 38.0 0.00011 21.7 4.4 4.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 CDO73302.1 - 2.5e-10 39.8 0.0 0.0014 18.1 0.0 4.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IBR PF01485.16 CDO73302.1 - 6.5e-09 35.5 3.9 6.5e-09 35.5 2.7 2.7 2 0 0 2 2 2 1 IBR domain RRM_6 PF14259.1 CDO73302.1 - 4.1e-08 33.0 0.0 0.059 13.3 0.0 4.2 5 0 0 5 5 5 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 CDO73302.1 - 5.6e-08 32.6 4.2 5.6e-08 32.6 2.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO73302.1 - 4.3e-07 29.4 2.7 4.3e-07 29.4 1.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDO73302.1 - 8.4e-07 28.6 3.2 2.1e-06 27.3 2.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger RRM_5 PF13893.1 CDO73302.1 - 1e-06 28.4 0.0 0.013 15.3 0.0 3.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 CDO73302.1 - 2.2e-06 27.3 3.9 2.2e-06 27.3 2.7 3.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 CDO73302.1 - 0.00015 21.4 4.4 0.00015 21.4 3.0 2.3 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CDO73302.1 - 0.00023 20.7 3.7 0.00023 20.7 2.6 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDO73302.1 - 0.00037 20.3 7.8 0.00037 20.3 5.4 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF4079 PF13301.1 CDO73302.1 - 0.041 13.8 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) zf-CCCH_2 PF14608.1 CDO73302.1 - 0.33 11.0 37.4 3.7 7.7 0.4 4.8 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 CDO73303.1 - 1.3e-73 247.3 0.0 1.9e-73 246.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73303.1 - 2.2e-36 125.2 0.0 3.9e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO73303.1 - 5.7e-06 25.5 0.0 0.00014 20.9 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 CDO73303.1 - 0.066 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CytochromB561_N PF09786.4 CDO73303.1 - 0.073 11.5 1.9 0.12 10.8 1.3 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal APH PF01636.18 CDO73303.1 - 2.4 7.8 13.9 0.083 12.6 0.3 3.7 4 0 0 4 4 4 0 Phosphotransferase enzyme family DUF2962 PF11176.3 CDO73304.1 - 1.3e-23 83.2 19.4 4.6e-18 65.2 1.8 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF2962) Peptidase_M19 PF01244.16 CDO73304.1 - 0.046 12.6 0.1 0.061 12.2 0.1 1.1 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Spore_coat_CotO PF14153.1 CDO73304.1 - 1.2 8.5 14.6 0.64 9.4 6.6 2.1 2 0 0 2 2 2 0 Spore coat protein CotO PAT1 PF09770.4 CDO73306.1 - 8.7e-150 500.5 63.2 1.1e-124 417.4 0.3 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 DNA_ligase_A_M PF01068.16 CDO73307.1 - 1.9e-50 171.0 0.0 3.2e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CDO73307.1 - 1.5e-34 119.3 0.0 2.9e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CDO73307.1 - 4.4e-14 52.6 0.0 6.9e-13 48.8 0.0 2.7 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 CDO73307.1 - 5e-10 39.3 0.4 0.0025 17.9 0.0 3.6 2 2 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Leu_zip PF15294.1 CDO73307.1 - 0.062 12.4 1.6 0.68 8.9 0.1 2.4 2 0 0 2 2 2 0 Leucine zipper Fork_head PF00250.13 CDO73308.1 - 9.7e-21 73.6 0.0 1.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Fork head domain Adaptin_N PF01602.15 CDO73309.1 - 2.2e-142 475.1 6.1 2.5e-142 474.8 4.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CDO73309.1 - 1.2e-23 83.5 0.0 2.4e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CDO73309.1 - 9.2e-06 25.8 1.8 0.23 11.7 0.1 5.1 3 3 0 3 3 3 1 HEAT repeats Cnd1 PF12717.2 CDO73309.1 - 0.00096 19.0 4.1 0.088 12.6 0.7 3.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CDO73309.1 - 0.0028 17.5 2.1 60 4.1 0.0 5.5 5 0 0 5 5 5 0 HEAT repeat TIP120 PF08623.5 CDO73309.1 - 0.017 14.6 3.0 0.026 14.0 0.1 2.5 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Arm PF00514.18 CDO73309.1 - 0.034 13.9 0.4 95 3.0 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.1 CDO73309.1 - 0.13 12.2 0.5 3 7.8 0.0 2.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SF3b1 PF08920.5 CDO73310.1 - 1.4e-20 73.7 6.5 5.6e-20 71.8 4.1 2.3 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 CDO73310.1 - 8e-13 48.4 13.7 1.3e-05 25.3 0.0 7.3 6 2 3 9 9 9 3 HEAT repeats HEAT PF02985.17 CDO73310.1 - 5.9e-12 44.6 8.4 0.0031 17.4 0.1 9.7 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 CDO73310.1 - 1.3e-11 44.5 6.4 0.0047 17.3 0.0 8.7 7 2 2 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.15 CDO73310.1 - 9.7e-08 30.7 1.0 7.8e-05 21.1 0.6 3.4 1 1 0 1 1 1 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CDO73310.1 - 2.3e-07 31.1 2.0 0.26 11.7 0.0 5.3 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CDO73310.1 - 0.00016 21.1 1.7 0.68 9.2 0.0 3.9 3 1 0 3 3 3 2 CLASP N terminal NUC173 PF08161.7 CDO73310.1 - 0.0003 20.2 0.6 9 5.5 0.0 4.8 4 1 1 5 5 5 1 NUC173 domain MMS19_C PF12460.3 CDO73310.1 - 0.0082 14.9 0.0 5.1 5.7 0.0 3.7 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal Arm PF00514.18 CDO73310.1 - 0.01 15.6 1.4 9.5 6.2 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 CDO73310.1 - 0.055 13.3 5.8 29 4.4 0.1 5.3 7 0 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Dopey_N PF04118.9 CDO73310.1 - 0.18 10.5 0.4 3.1 6.5 0.0 2.9 3 1 1 4 4 4 0 Dopey, N-terminal NMO PF03060.10 CDO73311.1 - 1.3e-67 228.2 0.2 1.6e-67 228.0 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CDO73311.1 - 9.2e-05 21.4 0.4 0.00059 18.8 0.3 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CDO73311.1 - 0.0077 15.1 1.7 0.011 14.6 1.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PACT_coil_coil PF10495.4 CDO73312.1 - 1.4e-12 47.3 0.1 7.4e-12 45.0 0.1 2.4 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Reo_sigmaC PF04582.7 CDO73312.1 - 0.079 12.1 30.7 0.2 10.7 2.2 5.4 3 3 3 6 6 6 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CDO73312.1 - 8.1 4.7 95.9 0.015 13.7 13.6 5.3 2 2 3 5 5 5 0 AAA domain CDP-OH_P_transf PF01066.16 CDO73313.1 - 0.024 14.9 0.1 0.05 13.9 0.1 1.6 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase DUF1752 PF08550.5 CDO73314.1 - 3.1e-07 29.8 8.5 7.3e-07 28.6 5.9 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) BTB PF00651.26 CDO73315.1 - 9.4e-10 38.4 0.0 3.7e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 CDO73316.1 - 1.1e-10 41.4 0.0 0.00011 22.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain VPS9 PF02204.13 CDO73317.1 - 1.9e-32 111.3 0.2 6.8e-32 109.5 0.1 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 CDO73317.1 - 2.2e-10 39.7 0.0 6e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 CDO73317.1 - 0.00013 21.7 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 DMRTA motif BTB PF00651.26 CDO73318.1 - 1.5e-23 82.8 0.0 1.4e-05 24.9 0.0 5.0 4 0 0 4 4 4 3 BTB/POZ domain Methyltransf_11 PF08241.7 CDO73318.1 - 0.073 13.5 1.7 3.7 8.1 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain Orbi_VP5 PF00901.12 CDO73318.1 - 0.22 9.7 0.0 2.8 6.0 0.0 2.0 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 HMG_CoA_synt_C PF08540.5 CDO73319.1 - 4.5e-91 305.2 0.2 6e-91 304.8 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 CDO73319.1 - 7.9e-84 279.4 0.1 1.3e-83 278.7 0.0 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 CDO73319.1 - 0.0019 17.7 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 CDO73319.1 - 0.041 13.8 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal BTB PF00651.26 CDO73320.1 - 1.4e-06 28.2 0.0 0.00016 21.6 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 CDO73321.1 - 5.8e-21 74.5 0.0 5.2e-10 39.2 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Skp1_POZ PF03931.10 CDO73321.1 - 0.015 15.4 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Solute_trans_a PF03619.11 CDO73322.1 - 3.9e-62 210.0 14.8 8.4e-48 163.0 3.8 2.1 1 1 1 2 2 2 2 Organic solute transporter Ostalpha An_peroxidase PF03098.10 CDO73323.1 - 2.9e-36 124.9 1.5 2e-27 95.8 0.0 3.2 1 1 2 3 3 3 3 Animal haem peroxidase Coatomer_E PF04733.9 CDO73324.1 - 2.3e-32 112.3 0.1 8e-32 110.5 0.0 1.7 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.12 CDO73324.1 - 0.0038 17.0 4.0 9.5 6.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CDO73324.1 - 0.011 15.5 0.3 0.011 15.5 0.2 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CDO73324.1 - 0.11 12.3 0.1 8.5 6.4 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CDO73324.1 - 2.2 9.0 22.0 0.79 10.4 0.9 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat zinc-ribbons_6 PF07191.7 CDO73325.1 - 0.089 12.5 1.1 0.17 11.7 0.8 1.4 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.2 CDO73325.1 - 0.2 11.5 3.7 0.39 10.5 2.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon Rad9 PF04139.8 CDO73327.1 - 3.9e-35 121.1 0.0 5.9e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Rad9 Pkinase PF00069.20 CDO73328.1 - 3e-74 249.4 0.0 4.4e-74 248.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73328.1 - 8e-51 172.5 0.0 1.3e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CDO73328.1 - 6.4e-22 77.7 0.1 2.2e-21 76.0 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 CDO73328.1 - 0.00011 21.2 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO73328.1 - 0.0066 16.2 0.2 0.1 12.3 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CDO73328.1 - 0.023 13.7 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 CDO73328.1 - 0.038 13.2 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 DSHCT (NUC185) domain SinI PF08671.5 CDO73328.1 - 0.3 10.5 1.0 0.85 9.0 0.7 1.8 1 0 0 1 1 1 0 Anti-repressor SinI PIF1 PF05970.9 CDO73329.1 - 2.5e-62 210.9 0.6 1e-46 159.5 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CDO73329.1 - 9.2e-17 61.2 0.0 1.7e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 CDO73329.1 - 2e-07 29.2 0.2 1.5e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 CDO73329.1 - 4.7e-06 26.7 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 CDO73329.1 - 9.5e-05 22.4 0.0 0.00042 20.3 0.0 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CDO73329.1 - 0.00016 21.3 0.3 0.23 10.9 0.1 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CDO73329.1 - 0.00028 20.5 0.3 0.00067 19.3 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CDO73329.1 - 0.0013 18.8 0.4 0.0031 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 CDO73329.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ArgK PF03308.11 CDO73329.1 - 0.027 13.2 0.1 0.064 12.0 0.1 1.6 1 0 0 1 1 1 0 ArgK protein TrwB_AAD_bind PF10412.4 CDO73329.1 - 0.034 12.7 0.0 0.06 11.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 CDO73329.1 - 0.038 12.9 0.0 0.085 11.8 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 CDO73329.1 - 0.04 14.1 0.1 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CDO73329.1 - 0.063 13.1 0.0 0.34 10.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CDO73329.1 - 0.08 12.5 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 TMF_DNA_bd PF12329.3 CDO73329.1 - 0.17 11.7 1.3 4.7 7.0 0.4 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PI3_PI4_kinase PF00454.22 CDO73330.1 - 9.4e-46 156.1 0.0 1.8e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CDO73330.1 - 3.9e-13 48.5 0.2 9.2e-13 47.3 0.1 1.7 1 0 0 1 1 1 1 FATC domain TAN PF11640.3 CDO73330.1 - 8.4e-07 28.8 0.0 2.5e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FAT PF02259.18 CDO73330.1 - 0.00036 19.6 2.5 0.0012 17.9 1.7 1.9 1 1 0 1 1 1 1 FAT domain Pox_G5 PF04599.7 CDO73330.1 - 0.21 10.2 0.4 0.36 9.4 0.3 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein F-box-like PF12937.2 CDO73331.1 - 4.1e-13 48.8 1.4 1.5e-12 47.0 0.9 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 CDO73331.1 - 0.00047 19.8 0.2 2.7 7.8 0.0 4.3 3 1 0 3 3 3 1 Leucine rich repeat F-box PF00646.28 CDO73331.1 - 0.0026 17.3 1.0 0.02 14.5 0.4 2.9 2 1 0 2 2 2 1 F-box domain LRR_4 PF12799.2 CDO73331.1 - 0.0058 16.2 0.1 12 5.6 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) Med6 PF04934.9 CDO73331.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 MED6 mediator sub complex component F-box-like PF12937.2 CDO73332.1 - 5.2e-13 48.5 1.7 2.7e-12 46.2 0.9 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDO73332.1 - 0.00046 19.7 4.3 0.0042 16.7 0.1 3.9 4 0 0 4 4 4 1 F-box domain RNA_pol_Rpb4 PF03874.11 CDO73333.1 - 3.3e-24 85.1 0.6 4.5e-24 84.7 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Aa_trans PF01490.13 CDO73334.1 - 1e-72 244.8 21.8 1.4e-72 244.4 15.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TspO_MBR PF03073.10 CDO73334.1 - 0.0054 16.2 1.1 0.0054 16.2 0.8 2.1 2 0 0 2 2 2 1 TspO/MBR family SUZ PF12752.2 CDO73335.1 - 5.6e-15 55.6 2.8 5.6e-15 55.6 1.9 3.9 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 CDO73335.1 - 0.00012 21.6 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 R3H domain DUF4262 PF14081.1 CDO73335.1 - 0.011 15.8 0.0 0.066 13.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) BTB PF00651.26 CDO73336.1 - 7.4e-05 22.7 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF4609 PF15382.1 CDO73337.1 - 0.049 13.3 0.1 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) CheR PF01739.13 CDO73338.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF4218 PF13960.1 CDO73340.1 - 0.00083 18.8 2.1 0.0027 17.1 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) BTB PF00651.26 CDO73343.1 - 3.2e-11 43.2 0.1 3.1e-05 23.9 0.0 3.1 2 1 0 2 2 2 2 BTB/POZ domain FGGY_N PF00370.16 CDO73344.1 - 4.3e-25 88.4 0.0 6.4e-17 61.6 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CDO73344.1 - 5.8e-21 75.0 0.0 6.9e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF972 PF06156.8 CDO73345.1 - 0.0089 16.3 4.1 0.2 11.9 0.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF972) AAA_13 PF13166.1 CDO73345.1 - 0.044 12.2 4.2 0.091 11.2 2.9 1.5 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 CDO73345.1 - 0.05 13.2 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AKNA PF12443.3 CDO73345.1 - 0.075 13.0 0.5 0.32 11.0 0.2 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor Atg14 PF10186.4 CDO73345.1 - 0.11 11.3 5.3 1.5 7.6 0.8 3.0 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CDO73345.1 - 0.74 9.3 13.2 0.068 12.7 3.8 2.5 1 1 1 2 2 2 0 IncA protein NPV_P10 PF05531.7 CDO73345.1 - 0.82 9.9 3.2 4.3 7.6 1.0 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 CDO73345.1 - 1.1 7.8 6.2 0.77 8.3 2.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein SYCE1 PF15233.1 CDO73345.1 - 1.1 9.1 6.4 5.8 6.8 2.0 2.5 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 COG2 PF06148.6 CDO73345.1 - 2.2 8.1 5.3 0.62 9.9 1.2 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 CDO73345.1 - 3 6.8 6.3 0.25 10.3 0.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 FadA PF09403.5 CDO73345.1 - 4 7.4 12.9 9 6.3 0.4 2.8 2 1 0 3 3 3 0 Adhesion protein FadA Cluap1 PF10234.4 CDO73345.1 - 4.1 6.5 9.3 0.21 10.7 0.8 2.5 3 0 0 3 3 3 0 Clusterin-associated protein-1 DUF4246 PF14033.1 CDO73346.1 - 2.8e-120 402.3 0.0 3.7e-120 401.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 CDO73346.1 - 0.12 12.6 0.0 0.39 11.0 0.0 1.8 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PseudoU_synth_1 PF01416.15 CDO73347.1 - 2.2e-17 63.4 0.0 4.9e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase NIR_SIR_ferr PF03460.12 CDO73347.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain MTHFR PF02219.12 CDO73348.1 - 3.5e-108 361.0 0.0 4.6e-108 360.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ELMO_CED12 PF04727.8 CDO73349.1 - 2.9e-30 105.0 0.1 5.1e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 CDO73349.1 - 5.6e-11 42.4 0.1 2.7e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) Fungal_trans PF04082.13 CDO73351.1 - 1.8e-08 33.5 0.0 3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Actin PF00022.14 CDO73352.1 - 9.3e-18 63.8 0.0 3.1e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 Actin zf-C3HC4 PF00097.20 CDO73353.1 - 0.00053 19.5 12.8 0.00096 18.7 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO73353.1 - 0.0029 17.3 15.5 0.005 16.6 10.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CDO73353.1 - 0.011 15.5 11.1 0.026 14.4 7.7 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CDO73353.1 - 0.045 13.4 10.9 0.085 12.5 7.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO73353.1 - 0.049 13.3 11.3 0.13 11.9 7.2 2.1 1 1 0 1 1 1 0 zinc-RING finger domain CAF-1_p150 PF11600.3 CDO73353.1 - 0.055 12.8 12.0 0.084 12.2 8.3 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-C3HC4_2 PF13923.1 CDO73353.1 - 0.075 13.0 15.6 0.15 12.1 10.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3552 PF12072.3 CDO73353.1 - 0.14 11.3 20.3 0.38 9.9 14.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) zf-Apc11 PF12861.2 CDO73353.1 - 0.2 11.5 4.8 0.54 10.1 3.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CDO73353.1 - 0.24 11.5 9.2 0.53 10.4 6.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 CDO73353.1 - 0.85 9.4 7.6 2 8.2 5.3 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein APG6 PF04111.7 CDO73353.1 - 2.1 7.3 12.8 2.9 6.8 8.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CDO73353.1 - 2.8 5.6 3.7 3.6 5.3 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FimP PF09766.4 CDO73353.1 - 7.2 5.5 10.8 10 5.0 7.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein Baculo_IE-1 PF05290.6 CDO73353.1 - 8.8 6.0 7.2 25 4.5 4.9 1.8 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Aldo_ket_red PF00248.16 CDO73354.1 - 6.4e-36 123.6 0.0 1.6e-29 102.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DUF3792 PF12670.2 CDO73354.1 - 0.037 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) ORC5_C PF14630.1 CDO73355.1 - 5.7e-50 170.2 0.0 9.9e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Lzipper-MIP1 PF14389.1 CDO73356.1 - 0.095 12.8 6.6 0.058 13.5 1.9 2.6 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CytochromB561_N PF09786.4 CDO73356.1 - 6.7 5.0 10.7 2.2 6.6 5.3 1.7 1 1 0 1 1 1 0 Cytochrome B561, N terminal Bestrophin PF01062.16 CDO73358.1 - 1.8e-32 112.5 0.1 8.6e-32 110.2 0.0 1.8 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel tRNA-synt_2b PF00587.20 CDO73359.1 - 1.1e-66 223.6 0.1 1.7e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CDO73359.1 - 1.6e-20 72.8 0.0 3.3e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain EBP PF05241.7 CDO73360.1 - 3.5e-10 39.2 1.0 4.9e-10 38.7 0.7 1.1 1 0 0 1 1 1 1 Emopamil binding protein Dec-1 PF04624.9 CDO73360.1 - 0.6 9.7 4.6 1.3 8.7 3.2 1.4 1 0 0 1 1 1 0 Dec-1 repeat GOLGA2L5 PF15070.1 CDO73361.1 - 0.11 10.9 0.1 0.15 10.4 0.1 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF1192 PF06698.6 CDO73361.1 - 0.13 12.0 0.7 0.67 9.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) TIM PF00121.13 CDO73362.1 - 3.1e-92 308.0 0.0 3.5e-92 307.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 CDO73362.1 - 0.069 12.4 0.1 0.11 11.6 0.0 1.3 1 1 0 1 1 1 0 CutC family DUF3742 PF12553.3 CDO73363.1 - 3.2 8.2 10.0 0.19 12.2 2.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3742) EPL1 PF10513.4 CDO73364.1 - 1.9e-17 63.9 0.4 1.9e-17 63.9 0.3 2.5 2 0 0 2 2 2 1 Enhancer of polycomb-like PMI_typeI PF01238.16 CDO73365.1 - 6.9e-60 202.9 0.0 8.4e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I GMC_oxred_C PF05199.8 CDO73368.1 - 3e-18 66.4 0.1 7.2e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CDO73368.1 - 4.2e-18 65.5 0.0 7.3e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FHA PF00498.21 CDO73368.1 - 2.8e-15 56.1 0.1 1.2e-14 54.1 0.0 2.2 2 0 0 2 2 1 1 FHA domain zf-RING_2 PF13639.1 CDO73368.1 - 2.4e-08 33.6 11.7 4.1e-08 32.9 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain FAD_binding_2 PF00890.19 CDO73368.1 - 6.3e-06 25.2 0.0 4.7e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CDO73368.1 - 9.5e-06 24.7 0.2 0.00046 19.1 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase zf-rbx1 PF12678.2 CDO73368.1 - 2.5e-05 24.2 3.4 5e-05 23.3 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDO73368.1 - 0.00013 21.5 11.4 0.00023 20.7 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAD_binding_3 PF01494.14 CDO73368.1 - 0.00028 20.0 0.1 0.00047 19.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CDO73368.1 - 0.00031 20.6 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO73368.1 - 0.00043 18.8 0.1 0.00072 18.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 CDO73368.1 - 0.00051 19.2 0.0 0.00093 18.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CDO73368.1 - 0.0006 18.9 0.2 0.0033 16.5 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 CDO73368.1 - 0.00079 19.3 0.3 0.0025 17.7 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-Apc11 PF12861.2 CDO73368.1 - 0.002 17.9 2.2 0.0036 17.1 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Pyr_redox_3 PF13738.1 CDO73368.1 - 0.0034 17.4 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase zf-RING_5 PF14634.1 CDO73368.1 - 0.046 13.4 9.9 0.09 12.5 6.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CDO73368.1 - 0.056 13.1 7.7 0.1 12.2 5.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO73368.1 - 0.07 13.1 12.3 0.15 12.1 8.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GIDA PF01134.17 CDO73368.1 - 0.28 9.9 0.1 0.5 9.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A PHD PF00628.24 CDO73368.1 - 1 9.1 11.9 0.085 12.5 4.2 2.1 2 0 0 2 2 2 0 PHD-finger Fer2_3 PF13085.1 CDO73369.1 - 4.5e-34 116.5 0.1 6.5e-34 116.0 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CDO73369.1 - 0.00021 21.5 0.1 0.00021 21.5 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CDO73369.1 - 0.0013 18.4 1.4 0.0026 17.4 1.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.1 CDO73369.1 - 0.0032 17.8 0.0 0.0032 17.8 0.0 1.9 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CDO73369.1 - 0.028 14.4 5.8 0.078 13.0 4.0 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF3688 PF12461.3 CDO73369.1 - 0.062 13.6 1.0 5.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3688) Catalase PF00199.14 CDO73370.1 - 1.7e-185 616.2 0.2 2e-185 615.9 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CDO73370.1 - 1.1e-16 60.4 1.1 1.6e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Ribosomal_L14 PF00238.14 CDO73371.1 - 3.9e-34 117.0 0.0 4.3e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RRM_1 PF00076.17 CDO73372.1 - 4.5e-17 61.4 0.0 7.3e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO73372.1 - 2.4e-15 56.2 0.0 7.6e-15 54.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO73372.1 - 3.7e-11 42.7 0.0 5.7e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO73372.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PSD4 PF07631.6 CDO73374.1 - 0.041 14.2 0.1 0.14 12.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) Aldo_ket_red PF00248.16 CDO73375.1 - 5.4e-65 219.0 0.1 6.1e-65 218.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 CDO73376.1 - 5e-14 51.8 0.1 8.7e-14 51.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain An_peroxidase PF03098.10 CDO73377.1 - 1.3e-73 248.1 0.0 2.6e-71 240.6 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase DUF2235 PF09994.4 CDO73378.1 - 1.5e-81 273.7 0.3 6.9e-64 215.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 CDO73378.1 - 0.0082 15.9 0.0 0.031 14.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2235 PF09994.4 CDO73379.1 - 6.1e-77 258.6 0.1 8e-77 258.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 CDO73379.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3850 PF12961.2 CDO73379.1 - 0.035 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) DUF2235 PF09994.4 CDO73380.1 - 1.2e-71 241.2 0.0 4.8e-71 239.3 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 CDO73380.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3850 PF12961.2 CDO73380.1 - 0.1 12.5 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3850) BAAT_C PF08840.6 CDO73380.1 - 0.14 11.8 0.0 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Polysacc_deac_1 PF01522.16 CDO73381.1 - 4.2e-05 23.1 0.3 0.00017 21.2 0.2 2.0 1 1 0 1 1 1 1 Polysaccharide deacetylase RseC_MucC PF04246.7 CDO73382.1 - 0.082 12.4 0.8 0.24 10.9 0.5 1.7 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF4059 PF13268.1 CDO73382.1 - 0.44 10.7 3.5 0.59 10.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4059) O-FucT PF10250.4 CDO73384.1 - 6.2e-07 28.8 0.0 9.6e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Pectate_lyase_3 PF12708.2 CDO73384.1 - 0.0017 18.5 0.0 0.0055 16.8 0.1 1.9 2 0 0 2 2 2 1 Pectate lyase superfamily protein Glyco_hydro_28 PF00295.12 CDO73384.1 - 0.02 13.8 0.2 0.028 13.3 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 tRNA-synt_His PF13393.1 CDO73385.1 - 6e-40 137.2 0.6 1.2e-35 123.0 0.0 2.9 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CDO73385.1 - 7.6e-20 71.1 0.0 2e-19 69.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CDO73385.1 - 2.6e-10 40.0 0.2 5.5e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.2 CDO73385.1 - 0.0044 16.2 0.1 0.019 14.0 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs FtsK_SpoIIIE PF01580.13 CDO73385.1 - 0.038 13.4 0.3 0.12 11.8 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family tRNA-synt_2d PF01409.15 CDO73385.1 - 0.066 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Ank_2 PF12796.2 CDO73386.1 - 1.7e-09 37.9 0.1 6.3e-08 32.8 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDO73386.1 - 1.1e-07 31.2 0.1 0.00086 19.0 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CDO73386.1 - 4.8e-07 30.1 0.0 0.038 14.5 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO73386.1 - 1.5e-06 27.8 0.2 0.082 13.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CDO73386.1 - 8.8e-06 25.8 0.0 0.0013 18.9 0.0 3.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Amidohydro_1 PF01979.15 CDO73387.1 - 5.6e-20 72.2 0.1 1.2e-19 71.1 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 CDO73387.1 - 7e-10 39.4 2.8 1.3e-06 28.6 0.1 2.8 1 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 CDO73387.1 - 2.3e-09 36.9 0.2 1.6e-08 34.2 0.1 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 CDO73387.1 - 2.2e-05 23.8 0.3 0.0019 17.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF1115 PF06544.7 CDO73388.1 - 4.2e-13 49.0 0.0 6.6e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RRM_1 PF00076.17 CDO73389.1 - 2.2e-17 62.4 0.0 3e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO73389.1 - 1.1e-15 57.4 0.0 1.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO73389.1 - 6.8e-09 35.4 0.0 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hepatitis_core PF00906.15 CDO73389.1 - 0.026 14.1 0.7 0.026 14.1 0.5 1.8 2 0 0 2 2 2 0 Hepatitis core antigen COX5A PF02284.11 CDO73390.1 - 9.6e-42 141.3 0.2 1.2e-41 141.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Cas_Cas02710 PF09670.5 CDO73390.1 - 0.03 12.9 0.2 0.046 12.3 0.1 1.2 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) CK2S PF15011.1 CDO73390.1 - 0.049 13.4 0.0 0.083 12.6 0.0 1.3 1 1 0 1 1 1 0 Casein Kinase 2 substrate PUF PF00806.14 CDO73391.1 - 6.4e-11 41.1 0.1 0.0031 16.9 0.0 3.6 3 0 0 3 3 3 3 Pumilio-family RNA binding repeat Pkinase PF00069.20 CDO73392.1 - 5.9e-77 258.3 0.0 8.1e-77 257.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73392.1 - 1.5e-40 138.8 0.0 2.2e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO73392.1 - 9.7e-07 28.0 0.0 2.5e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like UBA_2 PF08587.6 CDO73392.1 - 2.4e-05 24.4 0.9 3.6e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) RIO1 PF01163.17 CDO73392.1 - 0.00015 21.1 0.1 0.00028 20.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CDO73392.1 - 0.01 15.5 2.4 0.25 11.0 0.4 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family YL1 PF05764.8 CDO73392.1 - 0.039 13.5 1.0 0.073 12.6 0.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein MFS_1 PF07690.11 CDO73393.1 - 7.6e-25 87.3 42.9 5.3e-15 54.9 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily COX7B PF05392.6 CDO73393.1 - 0.044 13.3 0.5 13 5.4 0.0 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB ATG22 PF11700.3 CDO73393.1 - 0.23 9.9 21.3 0.017 13.6 2.6 3.0 1 1 2 3 3 3 0 Vacuole effluxer Atg22 like DUF1319 PF07028.6 CDO73395.1 - 0.23 11.6 5.0 0.11 12.6 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) PhoU PF01895.14 CDO73395.1 - 0.24 11.8 2.7 0.19 12.2 0.3 2.0 2 1 0 2 2 2 0 PhoU domain IncA PF04156.9 CDO73395.1 - 0.51 9.9 11.1 0.39 10.2 5.8 1.8 2 0 0 2 2 2 0 IncA protein FlxA PF14282.1 CDO73395.1 - 0.64 9.9 7.7 1.6 8.7 5.2 1.8 1 1 0 1 1 1 0 FlxA-like protein APG6 PF04111.7 CDO73395.1 - 0.94 8.4 11.2 0.12 11.3 4.2 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF342 PF03961.8 CDO73395.1 - 2.7 6.3 5.6 0.52 8.6 1.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) TBPIP PF07106.8 CDO73395.1 - 3.9 7.0 8.7 0.39 10.2 2.8 1.6 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF726 PF05277.7 CDO73397.1 - 6.7e-122 406.6 1.3 9.1e-122 406.2 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 CDO73397.1 - 0.006 16.3 0.1 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Pex14_N PF04695.8 CDO73397.1 - 0.013 15.5 4.1 0.2 11.7 0.0 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_1 PF00561.15 CDO73397.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold SRP14 PF02290.10 CDO73398.1 - 8.9e-23 80.0 1.2 1.3e-22 79.4 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle 14kD protein TP_methylase PF00590.15 CDO73399.1 - 8.4e-41 139.9 2.6 1e-40 139.6 0.6 1.9 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 CDO73399.1 - 5.1e-12 45.9 0.1 9.2e-11 41.9 0.1 2.4 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CDO73399.1 - 3.5e-07 29.4 0.5 0.00028 20.1 0.0 2.8 3 0 0 3 3 3 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CDO73399.1 - 0.0056 15.6 0.0 0.013 14.4 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central GntR PF00392.16 CDO73400.1 - 0.1 12.0 0.0 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Abhydrolase_3 PF07859.8 CDO73401.1 - 2.1e-18 66.7 0.0 1.7e-17 63.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CDO73401.1 - 9e-18 64.0 0.0 2.2e-17 62.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CDO73401.1 - 2.3e-05 24.1 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO73401.1 - 9.3e-05 22.4 0.3 0.00014 21.8 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family SMC_N PF02463.14 CDO73402.1 - 7.4e-63 211.7 0.0 3.6e-62 209.4 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CDO73402.1 - 1.8e-26 92.4 0.0 7.7e-26 90.4 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CDO73402.1 - 1.4e-10 41.6 2.7 4.7e-06 26.7 0.6 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CDO73402.1 - 1.2e-08 35.5 26.3 1.2e-08 35.5 18.2 7.8 2 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 CDO73402.1 - 8.1e-07 28.4 0.0 1.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Myosin_tail_1 PF01576.14 CDO73402.1 - 1.9e-06 25.9 24.3 1.9e-06 25.9 16.8 5.1 4 1 1 5 5 5 3 Myosin tail Reo_sigmaC PF04582.7 CDO73402.1 - 7.1e-06 25.4 19.4 0.033 13.3 0.3 4.4 3 1 2 5 5 5 4 Reovirus sigma C capsid protein MMR_HSR1 PF01926.18 CDO73402.1 - 0.033 14.1 0.0 0.21 11.5 0.0 2.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 CDO73402.1 - 0.28 11.4 0.0 0.28 11.4 0.0 5.7 5 2 0 5 5 5 0 ABC transporter AAA_13 PF13166.1 CDO73402.1 - 5.9 5.2 106.8 0.11 10.8 12.1 6.3 4 2 3 7 7 7 0 AAA domain Pkinase PF00069.20 CDO73403.1 - 3.9e-38 131.0 0.0 1.2e-37 129.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73403.1 - 2.9e-19 69.1 0.0 4.5e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO73403.1 - 0.0046 15.9 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO73403.1 - 0.0078 15.9 0.0 0.039 13.6 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 CDO73405.1 - 4.6e-40 137.4 0.0 7e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73405.1 - 1.1e-29 103.3 0.0 1.5e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO73405.1 - 0.0016 18.2 0.7 0.033 13.9 0.0 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CDO73405.1 - 0.11 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like NAD_binding_2 PF03446.10 CDO73406.1 - 5.8e-24 84.7 0.0 8.7e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CDO73406.1 - 8.6e-08 32.2 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 CDO73406.1 - 2.6e-06 27.5 0.0 4.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CDO73406.1 - 2.6e-05 24.5 0.0 5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 CDO73406.1 - 0.13 12.2 0.0 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Mfp-3 PF04202.8 CDO73407.1 - 0.14 12.3 0.3 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 Foot protein 3 Fip1 PF05182.8 CDO73408.1 - 9.9e-21 72.7 0.9 1.6e-20 72.1 0.6 1.3 1 0 0 1 1 1 1 Fip1 motif HEAT_2 PF13646.1 CDO73409.1 - 0.00016 21.8 0.5 0.049 13.9 0.0 1.9 1 1 1 2 2 2 2 HEAT repeats Arm PF00514.18 CDO73409.1 - 0.0053 16.5 1.0 0.026 14.3 0.0 2.4 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CDO73409.1 - 0.023 14.7 0.1 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat DUF3518 PF12031.3 CDO73409.1 - 0.065 12.0 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) HEAT_EZ PF13513.1 CDO73409.1 - 0.084 13.3 0.2 1.5 9.3 0.1 2.7 2 1 1 3 3 3 0 HEAT-like repeat KAP PF05804.7 CDO73409.1 - 0.16 9.9 0.0 0.23 9.3 0.0 1.3 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) TPX2 PF06886.6 CDO73411.1 - 2.1e-07 30.8 23.0 5.5e-07 29.5 16.0 1.8 1 0 0 1 1 1 1 Targeting protein for Xklp2 (TPX2) UPF0564 PF10595.4 CDO73411.1 - 0.00029 19.8 6.0 0.00029 19.8 4.1 3.2 2 1 1 3 3 3 2 Uncharacterised protein family UPF0564 Endonuc_Holl PF10107.4 CDO73411.1 - 0.19 11.4 3.0 0.39 10.4 2.1 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Fasciclin PF02469.17 CDO73412.1 - 1e-09 38.4 0.0 1.9e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain Aldo_ket_red PF00248.16 CDO73413.1 - 9.5e-67 224.7 0.0 1.1e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Adap_comp_sub PF00928.16 CDO73414.1 - 4.9e-19 68.4 0.0 7.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CDO73414.1 - 9.6e-06 25.3 0.1 1.7e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ubiquitin PF00240.18 CDO73416.1 - 6.6e-35 118.3 0.7 8.9e-35 117.9 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CDO73416.1 - 4.9e-28 96.4 8.1 8e-28 95.7 5.6 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CDO73416.1 - 6.3e-20 70.6 0.7 9.6e-20 70.0 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CDO73416.1 - 8.9e-06 25.8 0.1 3.2e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CDO73416.1 - 0.00019 21.1 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CDO73416.1 - 0.0087 15.9 0.0 0.017 15.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CDO73416.1 - 0.017 15.3 0.0 0.018 15.1 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Utp14 PF04615.8 CDO73417.1 - 1.1e-155 519.8 63.2 3.9e-101 339.4 37.3 3.1 2 1 1 3 3 3 2 Utp14 protein DUF1574 PF07611.6 CDO73417.1 - 1 8.1 5.0 2.1 7.1 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) Nramp PF01566.13 CDO73418.1 - 1.8e-91 306.6 25.3 6.9e-51 173.1 4.8 2.5 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein PHD PF00628.24 CDO73420.1 - 1.4e-05 24.6 8.7 4.4e-05 23.0 4.4 2.4 2 0 0 2 2 2 1 PHD-finger DUF2310 PF10071.4 CDO73420.1 - 0.056 12.3 0.2 0.093 11.6 0.1 1.2 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) ING PF12998.2 CDO73421.1 - 4e-07 30.2 0.0 4.9e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DnaJ PF00226.26 CDO73422.1 - 3e-15 55.6 0.3 4.5e-15 55.1 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 CDO73422.1 - 4e-14 51.8 0.1 6e-14 51.2 0.1 1.2 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 CDO73422.1 - 0.049 13.2 0.1 0.096 12.2 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CDO73422.1 - 0.075 12.7 0.2 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain GvpK PF05121.7 CDO73424.1 - 0.12 12.2 0.3 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 Gas vesicle protein K HA2 PF04408.18 CDO73425.1 - 2.1e-20 72.6 0.2 5.6e-20 71.2 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CDO73425.1 - 8.5e-08 31.9 0.0 1.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO73425.1 - 4e-06 26.4 0.1 1.3e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CDO73425.1 - 0.011 15.8 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CDO73425.1 - 0.037 12.9 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 CDO73425.1 - 0.038 13.9 0.3 0.42 10.5 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain HA2 PF04408.18 CDO73426.1 - 8.6e-30 102.7 0.1 2.4e-29 101.3 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CDO73426.1 - 1e-29 102.6 0.0 2.1e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CDO73426.1 - 1e-12 47.7 0.0 3.2e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 CDO73426.1 - 2.1e-06 27.7 0.2 4e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 CDO73426.1 - 5e-06 26.1 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CDO73426.1 - 8.9e-05 21.5 0.0 0.00023 20.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CDO73426.1 - 0.00018 21.6 0.0 0.00061 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CDO73426.1 - 0.0064 16.0 0.0 0.049 13.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CDO73426.1 - 0.03 14.6 1.3 0.62 10.3 0.1 3.1 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 CDO73426.1 - 0.034 13.8 0.2 0.1 12.3 0.1 1.8 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 CDO73426.1 - 0.039 13.7 0.1 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 CDO73426.1 - 0.12 12.2 0.0 0.82 9.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain DIOX_N PF14226.1 CDO73427.1 - 6.5e-12 46.0 0.0 9.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Adaptin_N PF01602.15 CDO73429.1 - 5.9e-107 358.1 0.0 7.9e-107 357.7 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CDO73429.1 - 1.6e-07 31.4 14.1 0.00015 21.9 0.1 6.6 4 2 3 7 7 7 3 HEAT repeats Cnd1 PF12717.2 CDO73429.1 - 8.8e-07 28.9 2.6 0.024 14.4 0.0 3.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CDO73429.1 - 1e-05 25.2 2.8 8 6.8 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat DUF2435 PF10363.4 CDO73429.1 - 0.00031 20.5 1.9 1.3 8.9 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 CDO73429.1 - 0.00052 20.4 12.1 0.13 12.7 0.1 6.4 7 1 2 9 9 9 1 HEAT-like repeat Arm PF00514.18 CDO73429.1 - 0.0039 16.9 0.1 13 5.7 0.0 4.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat ParcG PF10274.4 CDO73429.1 - 0.0049 16.7 0.9 3.7 7.4 0.0 3.3 3 1 0 3 3 3 1 Parkin co-regulated protein Nipped-B_C PF12830.2 CDO73429.1 - 0.019 14.6 1.9 12 5.4 0.1 3.4 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus RasGEF_N_2 PF14663.1 CDO73429.1 - 0.065 13.1 0.3 1.7 8.5 0.0 2.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain BLVR PF06375.6 CDO73429.1 - 0.077 12.8 0.0 0.077 12.8 0.0 3.9 2 1 2 4 4 4 0 Bovine leukaemia virus receptor (BLVR) Pkinase PF00069.20 CDO73430.1 - 1.5e-71 240.6 0.0 2.1e-71 240.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73430.1 - 1.8e-51 174.6 0.0 2.6e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO73430.1 - 5.8e-05 22.1 0.0 0.001 18.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 CDO73430.1 - 0.0048 16.1 0.5 0.0087 15.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) PRCC PF10253.4 CDO73431.1 - 0.097 13.3 2.1 0.13 12.9 1.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF3806 PF12713.2 CDO73432.1 - 0.016 14.6 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) ADH_zinc_N PF00107.21 CDO73434.1 - 8e-32 109.5 0.1 1.3e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO73434.1 - 1.4e-14 55.0 0.2 6.8e-14 52.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO73434.1 - 0.00083 19.0 0.0 0.0042 16.8 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain SIS_2 PF13580.1 CDO73434.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 SIS domain TrkA_N PF02254.13 CDO73434.1 - 0.015 15.3 0.1 0.15 12.0 0.1 2.3 1 1 1 2 2 2 0 TrkA-N domain Y_phosphatase PF00102.22 CDO73435.1 - 1.1e-39 136.1 0.0 1.1e-37 129.6 0.0 3.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CDO73435.1 - 0.00042 20.3 0.0 0.00091 19.2 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 CDO73435.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain p450 PF00067.17 CDO73436.1 - 3e-52 177.6 0.0 9.4e-52 176.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CDO73437.1 - 1e-54 185.8 0.0 1.2e-54 185.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF946 PF06101.6 CDO73438.1 - 2.6e-10 38.9 0.6 4e-10 38.3 0.4 1.3 1 1 0 1 1 1 1 Plant protein of unknown function (DUF946) RabGAP-TBC PF00566.13 CDO73439.1 - 2e-44 151.6 0.0 2.7e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mg_trans_NIPA PF05653.9 CDO73441.1 - 2.9e-80 269.4 20.8 4e-80 268.9 14.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CDO73441.1 - 1.1e-05 25.4 6.7 1.1e-05 25.4 4.7 3.4 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 CDO73441.1 - 8.8e-05 22.6 5.8 8.8e-05 22.6 4.0 3.3 1 1 2 3 3 3 1 Multidrug resistance efflux transporter Tmemb_161AB PF10268.4 CDO73441.1 - 0.086 11.3 8.4 0.13 10.7 5.8 1.1 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB DUF2208 PF09973.4 CDO73441.1 - 0.16 11.1 4.9 0.34 10.1 3.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF843 PF05814.6 CDO73441.1 - 1.7 8.4 7.1 2 8.2 0.4 2.4 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Lactonase PF10282.4 CDO73442.1 - 3.5e-12 46.0 0.0 1.9e-08 33.8 0.0 3.0 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.6 CDO73442.1 - 0.0011 17.8 0.0 0.033 13.0 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1513) F-box-like PF12937.2 CDO73443.1 - 1.7e-05 24.4 2.0 4.4e-05 23.1 1.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO73443.1 - 0.0011 18.5 1.0 0.0025 17.4 0.7 1.7 1 0 0 1 1 1 1 F-box domain RPEL PF02755.10 CDO73443.1 - 0.023 14.0 0.1 0.072 12.4 0.0 1.9 2 0 0 2 2 2 0 RPEL repeat CutC PF03932.9 CDO73444.1 - 3.5e-39 134.1 0.0 4.3e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 CutC family PEP_mutase PF13714.1 CDO73444.1 - 0.018 14.2 0.1 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Cyt-b5 PF00173.23 CDO73445.1 - 2.4e-06 27.2 0.0 5.1e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 CDO73445.1 - 0.0012 18.3 0.2 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase BTB PF00651.26 CDO73446.1 - 0.038 13.9 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain p450 PF00067.17 CDO73447.1 - 9.1e-52 176.1 0.0 2.6e-46 158.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Bromodomain PF00439.20 CDO73448.1 - 1.8e-37 127.1 4.9 3.2e-20 71.8 0.2 2.5 2 0 0 2 2 2 2 Bromodomain DUF1700 PF08006.6 CDO73448.1 - 0.24 10.7 0.1 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) zf-DHHC PF01529.15 CDO73449.1 - 2e-38 131.5 7.8 2.5e-38 131.1 5.4 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 CDO73449.1 - 0.12 12.2 2.2 0.25 11.1 1.5 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Gar1 PF04410.9 CDO73451.1 - 1.6e-34 118.6 0.4 5.9e-34 116.7 0.3 2.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region SAS4 PF15460.1 CDO73451.1 - 0.00067 19.4 4.8 0.0018 18.0 3.3 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 CDO73451.1 - 0.00088 19.7 5.4 0.00088 19.7 3.7 3.7 4 1 0 4 4 4 1 PEHE domain Hydrophobin PF01185.13 CDO73454.1 - 8.8e-21 74.1 11.7 1.1e-20 73.8 8.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Kelch_3 PF13415.1 CDO73456.1 - 6.1e-26 89.9 7.2 3.7e-08 33.2 0.1 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CDO73456.1 - 3.2e-23 81.2 2.2 5.4e-05 23.0 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 CDO73456.1 - 9.7e-20 70.0 9.8 1.4e-06 27.9 0.0 5.5 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CDO73456.1 - 2.8e-19 68.4 7.6 3e-07 30.3 0.4 5.5 2 2 3 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CDO73456.1 - 3.2e-18 65.0 1.9 9.5e-07 28.2 0.8 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CDO73456.1 - 3e-14 52.1 8.3 0.0062 16.2 0.5 5.5 5 1 0 5 5 5 4 Kelch motif FlaC_arch PF05377.6 CDO73456.1 - 0.086 12.7 18.0 0.46 10.4 0.9 4.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 CDO73456.1 - 9.3 6.0 12.9 0.084 12.6 0.3 3.6 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) S1 PF00575.18 CDO73457.1 - 6.1e-73 240.9 19.2 3.3e-15 55.9 0.3 10.7 10 1 0 10 10 10 10 S1 RNA binding domain TPR_19 PF14559.1 CDO73457.1 - 2.9e-08 33.9 0.0 0.005 17.1 0.0 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDO73457.1 - 7.6e-07 29.6 0.0 0.083 13.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDO73457.1 - 1.1e-06 28.4 0.4 0.44 10.5 0.0 4.3 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDO73457.1 - 4.3e-06 26.8 0.0 0.25 12.0 0.0 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CDO73457.1 - 2.8e-05 23.3 2.0 0.0019 17.3 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 CDO73457.1 - 0.00098 19.4 0.0 6.4 7.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 CDO73457.1 - 0.0017 18.1 12.2 0.014 15.0 0.0 4.0 2 1 2 4 4 4 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 CDO73457.1 - 0.0027 17.2 0.0 0.0086 15.7 0.0 1.9 1 0 0 1 1 1 1 TPR repeat NRDE-2 PF08424.5 CDO73457.1 - 0.0049 15.7 9.5 0.015 14.2 5.1 2.4 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference Apc3 PF12895.2 CDO73457.1 - 0.0081 16.2 0.0 0.027 14.6 0.0 2.0 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CDO73457.1 - 0.036 13.9 0.2 8.4 6.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_pol_Rbc25 PF08292.7 CDO73457.1 - 9.7 6.4 7.7 29 4.8 0.0 4.8 5 0 0 5 5 4 0 RNA polymerase III subunit Rpc25 zf-met PF12874.2 CDO73458.1 - 1.5e-06 28.2 1.2 2.7e-06 27.3 0.6 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 CDO73458.1 - 0.015 14.5 0.6 0.031 13.5 0.4 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Ribonuclease PF00545.15 CDO73459.1 - 1e-15 57.5 0.2 1.6e-15 56.9 0.1 1.3 1 1 0 1 1 1 1 ribonuclease Drc1-Sld2 PF11719.3 CDO73461.1 - 6.4e-15 55.1 6.5 6.4e-15 55.1 4.5 3.7 1 1 1 2 2 2 1 DNA replication and checkpoint protein PCI PF01399.22 CDO73463.1 - 6e-18 65.0 0.0 1.9e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 PCI domain LUC7 PF03194.10 CDO73463.1 - 0.063 12.7 2.5 1.1 8.7 1.7 2.2 1 1 0 1 1 1 0 LUC7 N_terminus HTH_27 PF13463.1 CDO73463.1 - 0.078 13.3 0.2 1.6 9.1 0.0 2.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain MRP-S25 PF13741.1 CDO73464.1 - 5.6e-50 169.9 2.4 8.7e-49 166.0 1.6 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 Pal1 PF08316.6 CDO73467.1 - 0.024 15.0 0.1 0.024 15.0 0.0 2.5 3 1 1 4 4 4 0 Pal1 cell morphology protein GARS_A PF01071.14 CDO73468.1 - 3e-80 268.3 0.0 4.6e-80 267.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 CDO73468.1 - 4.9e-37 126.3 0.0 3e-36 123.8 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 CDO73468.1 - 4.6e-32 111.1 0.0 8.9e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 CDO73468.1 - 6.2e-27 93.6 0.1 1.4e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 CDO73468.1 - 7.7e-19 67.7 2.8 1.4e-17 63.7 0.8 3.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 CDO73468.1 - 6.7e-09 35.7 0.0 3.2e-08 33.5 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CDO73468.1 - 3.9e-06 25.8 0.0 9.7e-06 24.5 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 CDO73468.1 - 0.00023 20.4 0.0 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 CDO73468.1 - 0.0015 18.4 0.3 0.0036 17.1 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 CDO73468.1 - 0.04 13.4 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Ank_2 PF12796.2 CDO73469.1 - 5.2e-11 42.7 0.0 9.2e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDO73469.1 - 2.1e-10 39.8 0.0 2.2e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 CDO73469.1 - 4.7e-07 29.4 0.0 0.00026 20.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CDO73469.1 - 8.4e-07 29.3 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDO73469.1 - 9.3e-07 28.9 0.0 7e-06 26.1 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) zf-CCCH_2 PF14608.1 CDO73469.1 - 1.4e-05 24.8 15.0 0.0007 19.5 2.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 CDO73469.1 - 9.6e-05 21.9 11.1 0.016 14.8 1.7 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NAD_Gly3P_dh_C PF07479.9 CDO73470.1 - 1.4e-47 161.1 0.3 2e-47 160.6 0.2 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 CDO73470.1 - 3.7e-29 101.4 0.0 5.9e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 CDO73470.1 - 7.1e-07 28.7 0.0 1.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 CDO73470.1 - 2.4e-05 24.6 0.0 0.00018 21.8 0.0 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CDO73470.1 - 0.002 17.9 0.0 0.0057 16.5 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 CDO73470.1 - 0.049 13.6 0.0 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain PDH PF02153.12 CDO73470.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Syntaxin PF00804.20 CDO73471.1 - 1.2e-16 60.7 9.3 1.5e-16 60.4 2.6 2.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 CDO73471.1 - 1.8e-14 53.1 0.4 1.8e-14 53.1 0.3 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin-18_N PF10496.4 CDO73471.1 - 0.00084 19.1 5.0 0.011 15.5 0.1 3.6 3 1 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Sed5p PF11416.3 CDO73471.1 - 0.0085 15.5 0.1 0.026 13.9 0.1 1.9 1 0 0 1 1 1 1 Integral membrane protein Sed5p Cluap1 PF10234.4 CDO73471.1 - 0.032 13.4 9.8 0.056 12.6 2.7 2.4 2 1 0 2 2 2 0 Clusterin-associated protein-1 Osmo_CC PF08946.5 CDO73471.1 - 0.064 13.2 4.4 0.71 9.9 0.5 3.1 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Spectrin PF00435.16 CDO73471.1 - 0.24 11.7 7.2 0.58 10.4 0.2 3.1 2 1 1 3 3 2 0 Spectrin repeat DUF1664 PF07889.7 CDO73471.1 - 0.37 10.6 7.8 1.6 8.5 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.4 CDO73471.1 - 0.43 10.5 7.9 1.4 8.8 0.1 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein IncA PF04156.9 CDO73471.1 - 0.44 10.1 14.3 2.7 7.5 0.9 2.5 2 1 0 2 2 2 0 IncA protein SlyX PF04102.7 CDO73471.1 - 0.52 10.7 9.1 1.3 9.4 0.4 3.1 3 0 0 3 3 3 0 SlyX NPV_P10 PF05531.7 CDO73471.1 - 1.7 8.9 9.5 0.96 9.7 1.6 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF241 PF03087.9 CDO73471.1 - 3.3 7.1 9.4 1 8.7 2.1 2.5 2 1 1 3 3 3 0 Arabidopsis protein of unknown function Atg14 PF10186.4 CDO73471.1 - 4.9 5.9 14.0 8.5 5.2 1.2 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Synaptobrevin PF00957.16 CDO73471.1 - 9.3 5.9 8.1 0.95 9.1 0.4 2.9 3 0 0 3 3 3 0 Synaptobrevin DDE_3 PF13358.1 CDO73472.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO73472.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RRM_6 PF14259.1 CDO73473.1 - 6.7e-13 48.4 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO73473.1 - 6.1e-12 44.9 0.0 1.5e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO73473.1 - 0.0006 19.6 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 CDO73474.1 - 5.2e-35 119.9 0.2 7.1e-35 119.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CDO73474.1 - 0.006 16.4 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CDO73474.1 - 0.0096 15.5 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 UEV domain DIOX_N PF14226.1 CDO73475.1 - 0.00042 20.8 0.1 0.0012 19.3 0.1 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO73475.1 - 0.0035 17.5 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Chorismate_bind PF00425.13 CDO73476.1 - 3.4e-63 213.3 0.0 3.6e-57 193.6 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 CDO73476.1 - 3.1e-33 114.8 0.0 5e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 CDO73476.1 - 3.8e-22 78.8 0.0 9e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 CDO73476.1 - 0.0025 17.2 1.1 0.02 14.3 0.8 2.0 1 1 0 1 1 1 1 Peptidase C26 Pox_H7 PF04787.7 CDO73476.1 - 0.21 11.3 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 Late protein H7 HEAT PF02985.17 CDO73477.1 - 0.00099 19.0 1.0 0.085 12.9 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat Arrestin_C PF02752.17 CDO73478.1 - 1e-14 54.8 0.0 2.2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain adh_short_C2 PF13561.1 CDO73479.1 - 2.2e-24 86.5 0.0 2.8e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO73479.1 - 2.1e-18 66.7 0.1 8.3e-16 58.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CDO73479.1 - 7.9e-06 25.6 0.1 3.5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 CDO73479.1 - 0.0023 17.1 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ATP-gua_Ptrans PF00217.14 CDO73479.1 - 0.028 13.7 0.2 0.041 13.2 0.1 1.1 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain DUF605 PF04652.11 CDO73480.1 - 1.8e-76 258.0 53.5 1.2e-73 248.6 37.1 2.6 1 1 0 1 1 1 1 Vta1 like Pectinesterase PF01095.14 CDO73481.1 - 3.8e-21 74.9 5.2 2.6e-13 49.2 1.2 2.9 1 1 1 2 2 2 2 Pectinesterase RNase_T PF00929.19 CDO73483.1 - 0.00047 20.4 0.0 0.0007 19.9 0.0 1.4 1 1 0 1 1 1 1 Exonuclease PPR_3 PF13812.1 CDO73484.1 - 0.031 14.5 0.0 0.37 11.1 0.0 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TetR_C_6 PF13977.1 CDO73484.1 - 0.084 12.9 8.9 7.9 6.5 0.0 4.6 3 1 1 4 4 4 0 Bacterial transcriptional repressor Cut8_C PF08559.5 CDO73485.1 - 0.06 13.1 0.0 0.74 9.6 0.0 2.6 3 0 0 3 3 3 0 Cut8 six-helix bundle Cas1_AcylT PF07779.7 CDO73486.1 - 1.1e-160 535.3 18.4 2e-159 531.2 12.8 2.0 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 CDO73486.1 - 5.2e-24 85.4 0.0 8.7e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p CheX PF13690.1 CDO73486.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX Rhomboid PF01694.17 CDO73487.1 - 4e-35 120.9 15.8 4e-35 120.9 10.9 1.7 1 1 1 2 2 2 1 Rhomboid family P12 PF12669.2 CDO73487.1 - 3.9 7.7 5.2 0.39 10.9 0.1 2.0 2 0 0 2 2 2 0 Virus attachment protein p12 family SnoaL PF07366.7 CDO73488.1 - 0.0063 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DIL PF01843.14 CDO73489.1 - 3.3e-21 75.1 0.3 6e-21 74.2 0.2 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 CDO73489.1 - 1.2e-09 38.3 0.0 2.8e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDO73489.1 - 1.3e-08 34.2 0.1 7.1e-05 22.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CDO73489.1 - 2.5e-07 31.0 0.0 7.8e-05 23.0 0.0 3.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDO73489.1 - 6.5e-06 26.2 0.0 2.1e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO73489.1 - 0.00012 21.9 0.0 0.0078 16.3 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Rrp15p PF07890.7 CDO73490.1 - 2.7e-20 72.7 6.2 2.7e-20 72.7 4.3 2.8 1 1 1 2 2 2 1 Rrp15p HrpF PF06266.7 CDO73490.1 - 0.53 10.4 3.6 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 HrpF protein YL1 PF05764.8 CDO73490.1 - 2.9 7.4 22.6 9.9 5.6 15.7 1.9 1 1 0 1 1 1 0 YL1 nuclear protein CLTH PF10607.4 CDO73491.1 - 6e-39 133.0 0.3 8.4e-39 132.5 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CDO73491.1 - 1.5e-10 40.4 0.2 3.9e-10 39.1 0.2 1.8 1 0 0 1 1 1 1 LisH Pkinase PF00069.20 CDO73492.1 - 8.9e-68 228.2 0.0 1.3e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73492.1 - 1.5e-45 155.3 0.0 2.3e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO73492.1 - 6.9e-09 35.0 0.0 1.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CDO73492.1 - 0.0019 17.2 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ras_bdg_2 PF14847.1 CDO73492.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 MRP-S28 PF10213.4 CDO73494.1 - 3.9e-30 104.5 0.0 6e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein CN_hydrolase PF00795.17 CDO73495.1 - 3e-24 85.4 0.0 3.9e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Septin PF00735.13 CDO73496.1 - 3.7e-122 406.7 0.0 3.7e-122 406.7 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CDO73496.1 - 1.5e-06 28.1 0.0 3.5e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CDO73496.1 - 3.1e-05 23.1 0.2 0.00023 20.3 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CDO73496.1 - 0.00019 21.7 4.7 0.04 14.2 0.0 2.7 3 0 0 3 3 3 2 ABC transporter GTP_EFTU PF00009.22 CDO73496.1 - 0.0004 19.8 0.7 0.033 13.6 0.0 3.2 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CDO73496.1 - 0.0012 18.9 0.0 0.0086 16.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain Ras PF00071.17 CDO73496.1 - 0.0029 17.0 0.0 0.021 14.1 0.0 2.3 2 0 0 2 2 2 1 Ras family AIG1 PF04548.11 CDO73496.1 - 0.0058 15.7 0.4 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 AIG1 family AAA_10 PF12846.2 CDO73496.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 CDO73496.1 - 0.016 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 CDO73496.1 - 0.028 14.9 0.0 0.23 11.9 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 CDO73496.1 - 0.031 14.0 5.0 0.7 9.6 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.1 CDO73496.1 - 0.032 14.2 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 CDO73496.1 - 0.058 12.9 0.4 13 5.1 0.1 3.2 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 CDO73496.1 - 0.081 12.6 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Strep_SA_rep PF06696.6 CDO73496.1 - 0.25 11.1 5.5 0.094 12.5 1.0 2.2 1 1 1 2 2 2 0 Streptococcal surface antigen repeat IncA PF04156.9 CDO73496.1 - 0.48 9.9 4.9 0.77 9.3 3.4 1.2 1 0 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 CDO73496.1 - 0.5 9.4 5.5 0.91 8.6 3.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_24 PF13479.1 CDO73496.1 - 0.54 9.7 2.8 0.34 10.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain Xpo1 PF08389.7 CDO73497.1 - 2.1e-24 86.1 3.5 3.9e-23 81.9 0.0 4.1 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 CDO73497.1 - 3.8e-06 26.7 0.1 0.0011 18.8 0.0 3.0 2 1 1 3 3 3 2 Importin-beta N-terminal domain HEAT_EZ PF13513.1 CDO73497.1 - 0.00068 20.0 2.4 0.54 10.8 0.0 4.6 5 0 0 5 5 5 2 HEAT-like repeat CoA_binding PF02629.14 CDO73498.1 - 3.2e-29 101.2 0.9 4.2e-29 100.9 0.0 1.6 2 0 0 2 2 2 1 CoA binding domain CoA_binding_2 PF13380.1 CDO73498.1 - 1.6e-06 28.2 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 CDO73498.1 - 0.00099 19.6 0.0 0.0018 18.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ligase_CoA PF00549.14 CDO73498.1 - 0.039 13.5 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 CoA-ligase Succ_CoA_lig PF13607.1 CDO73498.1 - 0.1 12.2 2.8 0.13 11.9 0.2 2.3 3 0 0 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain Ank_5 PF13857.1 CDO73499.1 - 1.8e-15 56.5 0.1 2.1e-14 53.1 0.1 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CDO73499.1 - 2.4e-14 53.4 0.4 7e-14 51.9 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDO73499.1 - 7.1e-13 47.6 0.7 8.9e-12 44.1 0.0 3.0 4 0 0 4 4 4 1 Ankyrin repeat ACBP PF00887.14 CDO73499.1 - 1.5e-12 46.9 0.0 2.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ligase_CoA PF00549.14 CDO73499.1 - 1.8e-11 43.8 0.0 3.1e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Ank_3 PF13606.1 CDO73499.1 - 6.3e-10 38.3 0.5 2.7e-08 33.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CDO73499.1 - 1.7e-09 37.9 0.3 2.5e-08 34.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ribosomal_S16 PF00886.14 CDO73500.1 - 3.1e-21 74.8 0.1 4.6e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 LSM PF01423.17 CDO73501.1 - 2.5e-21 74.9 0.1 2.8e-21 74.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain UPF0565 PF10561.4 CDO73501.1 - 0.084 11.7 0.0 0.093 11.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Arm PF00514.18 CDO73502.1 - 2e-90 293.8 21.9 1.9e-12 46.5 0.0 10.7 11 0 0 11 11 10 9 Armadillo/beta-catenin-like repeat 2-Hacid_dh_C PF02826.14 CDO73502.1 - 1.6e-52 177.2 0.0 2.8e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HEAT_2 PF13646.1 CDO73502.1 - 3.9e-37 126.4 9.1 1.4e-11 44.4 0.0 8.8 3 2 4 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 CDO73502.1 - 1.6e-26 92.0 13.0 4e-09 36.6 0.0 8.4 7 1 0 8 8 7 4 HEAT-like repeat PC_rep PF01851.17 CDO73502.1 - 4.1e-26 89.6 10.6 6.8e-08 32.3 0.0 8.8 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT PF02985.17 CDO73502.1 - 4.3e-24 82.3 4.5 5.7e-05 22.8 0.0 10.1 10 0 0 10 10 9 4 HEAT repeat IBB PF01749.15 CDO73502.1 - 5.2e-20 71.4 0.9 1.3e-19 70.1 0.6 1.7 1 0 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.15 CDO73502.1 - 1.2e-08 33.7 0.0 0.00088 17.7 0.0 3.8 2 1 2 4 4 4 2 Adaptin N terminal region 2-Hacid_dh PF00389.25 CDO73502.1 - 2.3e-08 33.5 0.0 5.2e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Arm_2 PF04826.8 CDO73502.1 - 5.6e-07 28.9 0.0 0.1 11.7 0.0 5.3 3 2 3 6 6 6 2 Armadillo-like RICTOR_V PF14668.1 CDO73502.1 - 6.3e-06 26.0 1.2 0.52 10.2 0.0 5.3 4 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 CDO73502.1 - 0.002 18.4 7.9 2.1 9.0 0.0 7.0 8 0 0 8 8 6 1 PBS lyase HEAT-like repeat NAD_binding_2 PF03446.10 CDO73502.1 - 0.0066 16.3 0.1 0.029 14.2 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase V-ATPase_H_C PF11698.3 CDO73502.1 - 0.024 14.5 0.0 6.5 6.7 0.0 4.4 5 1 0 5 5 4 0 V-ATPase subunit H Proteasom_PSMB PF10508.4 CDO73502.1 - 0.091 11.0 0.0 0.71 8.0 0.0 2.5 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Mo25 PF08569.6 CDO73502.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 Mo25-like Apc3 PF12895.2 CDO73502.1 - 0.12 12.5 0.4 0.75 9.9 0.1 2.6 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 COX6A PF02046.10 CDO73503.1 - 2.1e-27 95.3 0.0 2.3e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Retrotrans_gag PF03732.12 CDO73505.1 - 0.024 14.7 0.1 0.045 13.8 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein DUF2890 PF11081.3 CDO73505.1 - 0.27 11.2 4.9 0.42 10.6 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) GH-E PF14410.1 CDO73505.1 - 0.32 11.1 2.0 0.61 10.2 1.4 1.4 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Ribul_P_3_epim PF00834.14 CDO73506.1 - 2.3e-55 186.8 0.0 5.5e-27 94.1 0.0 2.0 2 0 0 2 2 2 2 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.5 CDO73506.1 - 0.045 13.7 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Gly_transf_sug PF04488.10 CDO73507.1 - 4e-07 30.3 0.0 9.1e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 CDO73507.1 - 0.00059 19.0 0.4 0.00091 18.4 0.2 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 CDO73507.1 - 0.012 14.0 0.1 0.02 13.4 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DEAD PF00270.24 CDO73508.1 - 9.3e-20 70.7 0.0 6.2e-19 68.1 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO73508.1 - 8e-08 32.0 0.0 2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CDO73508.1 - 0.071 12.1 0.1 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 CDO73508.1 - 0.096 12.5 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF4203 PF13886.1 CDO73509.1 - 3.2e-39 134.5 28.1 4.5e-39 134.1 19.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF3357 PF11837.3 CDO73509.1 - 0.036 13.9 1.7 0.061 13.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF2681 PF10883.3 CDO73509.1 - 1.6 8.9 4.5 0.77 10.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) GAS PF13851.1 CDO73510.1 - 0.19 10.9 3.3 0.27 10.4 2.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding LAG1-DNAbind PF09271.6 CDO73511.1 - 2.1e-27 96.2 0.1 1.7e-24 86.9 0.2 3.2 2 1 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 CDO73511.1 - 1.9e-17 63.4 0.0 3.5e-16 59.3 0.0 2.4 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain Sugar_tr PF00083.19 CDO73512.1 - 1e-81 274.8 14.7 8e-65 219.1 7.5 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CDO73512.1 - 5.5e-21 74.6 30.0 1.2e-18 66.9 6.7 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily PPR_2 PF13041.1 CDO73514.1 - 2.7e-42 142.5 2.0 9e-09 35.1 0.0 10.2 4 3 7 11 11 11 9 PPR repeat family PPR_3 PF13812.1 CDO73514.1 - 2.7e-24 83.3 24.4 0.0024 18.0 0.0 12.8 13 1 0 13 13 13 6 Pentatricopeptide repeat domain PPR PF01535.15 CDO73514.1 - 3.3e-19 67.4 17.9 0.0047 16.8 0.0 10.6 12 1 0 12 12 12 6 PPR repeat PPR_1 PF12854.2 CDO73514.1 - 2.2e-13 49.3 0.1 0.00093 18.6 0.0 8.5 9 0 0 9 9 9 3 PPR repeat TPR_14 PF13428.1 CDO73514.1 - 0.0025 18.3 16.4 0.064 13.9 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 CDO73514.1 - 0.009 15.6 1.9 15 5.3 0.0 3.6 3 0 0 3 3 3 1 TPR repeat YodL PF14191.1 CDO73514.1 - 0.17 12.3 0.2 28 5.2 0.0 2.8 2 0 0 2 2 2 0 YodL-like Pro_isomerase PF00160.16 CDO73515.1 - 9.5e-44 149.3 0.0 1.5e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 CDO73515.1 - 4.4e-07 29.3 0.4 5.1e-05 22.5 0.0 2.8 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 CDO73515.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.3 CDO73515.1 - 0.075 12.5 0.0 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Snf7 PF03357.16 CDO73516.1 - 7.5e-13 48.2 3.3 7.5e-13 48.2 2.3 1.9 2 0 0 2 2 2 1 Snf7 Fungal_trans PF04082.13 CDO73516.1 - 1.7e-08 33.6 0.0 3.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain G_glu_transpept PF01019.16 CDO73517.1 - 1.7e-144 482.0 0.0 2e-144 481.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PP2C PF00481.16 CDO73518.1 - 9.1e-27 94.0 0.0 5.5e-23 81.6 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CDO73518.1 - 0.00019 20.9 0.0 0.00046 19.6 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C His_Phos_2 PF00328.17 CDO73519.1 - 1.6e-45 155.9 0.0 2e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_M41 PF01434.13 CDO73520.1 - 7.8e-73 244.4 0.0 1.1e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CDO73520.1 - 5.5e-42 143.1 0.0 1.1e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CDO73520.1 - 1.1e-12 48.0 0.0 2.9e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular RuvB_N PF05496.7 CDO73520.1 - 0.00063 18.8 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CDO73520.1 - 0.00082 20.1 0.0 0.0024 18.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CDO73520.1 - 0.0019 18.3 0.1 0.061 13.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO73520.1 - 0.0034 17.1 0.3 0.01 15.5 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 CDO73520.1 - 0.0044 15.7 0.1 0.0086 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 CDO73520.1 - 0.0059 16.3 0.1 0.03 14.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CDO73520.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 CDO73520.1 - 0.015 15.3 0.1 0.093 12.7 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain AAA_2 PF07724.9 CDO73520.1 - 0.017 15.0 0.1 0.076 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CDO73520.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CDO73520.1 - 0.12 11.7 0.8 0.33 10.3 0.3 1.7 1 1 0 2 2 2 0 AAA domain PhaP_Bmeg PF09602.5 CDO73520.1 - 0.15 11.9 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) AAA_28 PF13521.1 CDO73520.1 - 0.19 11.6 0.6 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 CDO73521.1 - 2.8e-10 39.4 17.8 4.3e-10 38.8 12.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 CDO73522.1 - 1.8e-28 99.2 32.2 1.8e-28 99.2 22.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0113 PF03657.8 CDO73523.1 - 3.7e-10 39.7 0.0 4.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 CDO73523.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.9 1 1 1 2 2 2 0 pre-rRNA processing and ribosome biogenesis DEAD PF00270.24 CDO73525.1 - 1.9e-11 43.7 0.0 4.5e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO73525.1 - 0.00023 20.9 0.2 0.0007 19.4 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO73525.1 - 0.0027 17.5 0.0 0.054 13.3 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-4CXXC_R1 PF10497.4 CDO73525.1 - 0.21 11.7 1.7 0.47 10.6 1.2 1.5 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Sec39 PF08314.6 CDO73526.1 - 2.5e-52 177.8 0.0 4.3e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Secretory pathway protein Sec39 RVT_1 PF00078.22 CDO73528.1 - 3.3e-19 69.0 0.0 6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO73528.1 - 2.6e-14 53.7 0.0 5.7e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO73528.1 - 0.028 14.7 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Cgr1 PF03879.9 CDO73529.1 - 1.8e-16 60.2 27.3 1.5e-15 57.3 17.9 2.0 2 0 0 2 2 2 1 Cgr1 family Atg14 PF10186.4 CDO73529.1 - 0.0013 17.7 6.7 0.0013 17.7 4.6 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF3682 PF12446.3 CDO73529.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) RF-1 PF00472.15 CDO73529.1 - 0.047 13.4 6.1 0.065 13.0 4.2 1.4 1 0 0 1 1 1 0 RF-1 domain DUF4168 PF13767.1 CDO73529.1 - 0.05 14.2 2.7 0.085 13.5 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) V_ATPase_I PF01496.14 CDO73529.1 - 0.14 9.9 6.7 0.17 9.7 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CDO73529.1 - 0.73 8.8 9.7 0.88 8.5 6.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PBP_sp32 PF07222.7 CDO73529.1 - 0.94 8.5 9.6 1.3 8.1 6.3 1.5 1 1 1 2 2 2 0 Proacrosin binding protein sp32 DUF1682 PF07946.9 CDO73529.1 - 1.7 7.4 15.0 2.1 7.0 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pep3_Vps18 PF05131.9 CDO73530.1 - 2.7e-42 143.6 0.0 4.7e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CDO73530.1 - 6.8e-14 51.6 0.7 6.3e-05 22.6 0.1 4.0 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.4 CDO73530.1 - 0.00011 22.2 0.0 0.00028 21.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 CDO73530.1 - 0.00038 20.1 1.5 0.00091 18.8 1.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CDO73530.1 - 0.0025 17.6 2.0 0.0069 16.2 1.4 1.7 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.1 CDO73530.1 - 0.085 12.5 6.3 2.2 7.9 3.9 3.2 2 1 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 CDO73530.1 - 0.2 11.6 8.2 1.8 8.6 0.4 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 CDO73530.1 - 0.52 10.3 1.9 1.1 9.2 1.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.1 CDO73530.1 - 1.2 9.0 6.5 1.4 8.8 0.3 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CDO73530.1 - 5.8 6.6 7.5 0.73 9.5 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NRDE-2 PF08424.5 CDO73531.1 - 6.4e-24 84.4 3.7 6.4e-24 84.4 2.6 1.7 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference Spc7 PF08317.6 CDO73531.1 - 0.084 11.5 2.4 0.59 8.7 0.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein MIP-T3 PF10243.4 CDO73531.1 - 3.1 6.1 29.7 6.6 5.0 20.6 1.4 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 PSD4 PF07631.6 CDO73532.1 - 0.056 13.8 0.1 0.11 12.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) PSD4 PF07631.6 CDO73533.1 - 0.059 13.7 0.1 0.11 12.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) CBM_19 PF03427.8 CDO73536.1 - 3.2e-08 33.2 11.9 0.00075 19.2 3.4 2.7 2 0 0 2 2 2 2 Carbohydrate binding domain (family 19) Colipase_C PF02740.9 CDO73536.1 - 0.069 12.9 2.3 8.6 6.2 0.1 2.7 2 0 0 2 2 2 0 Colipase, C-terminal domain PocR PF10114.4 CDO73536.1 - 0.41 9.7 2.0 5.5 6.1 0.1 2.3 2 0 0 2 2 2 0 Sensory domain found in PocR Utp21 PF04192.7 CDO73537.1 - 2.7e-65 219.8 4.2 4.1e-65 219.1 2.9 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CDO73537.1 - 7.6e-20 70.0 8.9 3.2e-06 26.8 0.0 8.1 8 0 0 8 8 8 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CDO73537.1 - 9.5e-05 21.3 1.1 2.3 6.8 0.0 4.3 2 2 0 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 CDO73537.1 - 0.003 17.0 0.1 0.02 14.3 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain Utp12 PF04003.7 CDO73537.1 - 0.0046 16.8 1.3 0.01 15.7 0.9 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Hira PF07569.6 CDO73537.1 - 0.068 12.3 3.6 0.2 10.8 0.1 3.4 4 1 1 5 5 5 0 TUP1-like enhancer of split DUF815 PF05673.8 CDO73539.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Gln-synt_C PF00120.19 CDO73541.1 - 2.1e-57 194.2 0.0 1.3e-56 191.6 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF3074 PF11274.3 CDO73542.1 - 1.7e-38 132.1 1.3 2.3e-38 131.6 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.14 CDO73542.1 - 0.00046 19.5 0.1 0.0006 19.1 0.1 1.1 1 0 0 1 1 1 1 START domain F-box-like PF12937.2 CDO73543.1 - 1.3e-05 24.8 0.4 4.6e-05 23.0 0.3 2.1 1 0 0 1 1 1 1 F-box-like Ribosomal_L27 PF01016.14 CDO73544.1 - 5.1e-31 106.3 0.4 6.8e-31 105.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.1 CDO73544.1 - 0.055 12.7 0.3 0.28 10.4 0.1 2.3 2 1 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region eRF1_1 PF03463.10 CDO73544.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 eRF1 domain 1 mRNA_cap_enzyme PF01331.14 CDO73545.1 - 1.6e-48 164.9 0.3 4.9e-48 163.3 0.1 1.9 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain Skp1 PF01466.14 CDO73545.1 - 3.9e-37 126.1 0.7 8.6e-37 125.0 0.5 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CDO73545.1 - 6.6e-24 83.7 0.3 1.9e-23 82.3 0.1 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DNA_ligase_A_M PF01068.16 CDO73545.1 - 7.4e-11 41.8 0.0 4e-09 36.1 0.0 2.8 2 1 0 2 2 2 1 ATP dependent DNA ligase domain BTB PF00651.26 CDO73545.1 - 0.01 15.8 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF3446 PF11928.3 CDO73546.1 - 3.2 8.0 8.4 5.3 7.3 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3446) Amidohydro_5 PF13594.1 CDO73547.1 - 0.00027 20.7 0.0 0.00049 19.8 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Lipase_3 PF01764.20 CDO73548.1 - 3.2e-08 33.3 0.0 6.9e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 CDO73548.1 - 0.0057 16.4 0.1 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 CDO73548.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO73548.1 - 0.04 13.8 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CDO73548.1 - 0.061 12.9 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein MARVEL PF01284.18 CDO73549.1 - 3.2 7.5 9.4 12 5.7 0.1 2.5 2 1 0 2 2 2 0 Membrane-associating domain CTP_transf_2 PF01467.21 CDO73550.1 - 5e-06 26.6 0.0 2.3e-05 24.4 0.0 2.1 2 1 0 2 2 2 1 Cytidylyltransferase LIM PF00412.17 CDO73551.1 - 1.8e-11 43.8 11.7 5.3e-06 26.4 1.5 3.2 3 0 0 3 3 3 3 LIM domain WRC PF08879.5 CDO73551.1 - 0.013 15.1 0.7 7.9 6.2 0.1 3.1 2 0 0 2 2 2 0 WRC Sgf11 PF08209.6 CDO73552.1 - 0.058 12.7 0.4 0.13 11.6 0.2 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Transposase_21 PF02992.9 CDO73553.1 - 5.9e-15 54.9 0.1 1.8e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Transposase family tnp2 Zn_clus PF00172.13 CDO73555.1 - 8.3e-10 38.4 4.4 1.7e-09 37.3 3.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CDO73555.1 - 8.7e-07 28.0 0.2 5.3e-05 22.2 0.0 2.6 1 1 1 2 2 2 2 Fungal specific transcription factor domain BAF1_ABF1 PF04684.8 CDO73555.1 - 7.1 5.3 10.3 13 4.4 7.1 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mito_fiss_reg PF05308.6 CDO73556.1 - 9.3 5.5 7.6 1.7 7.9 1.5 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Syja_N PF02383.13 CDO73557.1 - 1.5e-75 253.9 0.0 2.4e-75 253.2 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 CDO73557.1 - 1.5e-27 95.2 0.0 3e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase Herpes_UL4 PF03277.8 CDO73557.1 - 0.034 13.4 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL4 family Proteasome PF00227.21 CDO73558.1 - 2.1e-51 173.9 0.2 2.5e-51 173.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit UQ_con PF00179.21 CDO73559.1 - 5.3e-49 165.2 0.0 6e-49 165.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDO73559.1 - 7.7e-06 25.6 0.0 9.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CDO73559.1 - 0.064 13.1 1.2 0.11 12.3 0.8 1.7 1 1 0 1 1 1 0 RWD domain Ribosomal_L7Ae PF01248.21 CDO73560.1 - 2.2e-25 88.0 0.0 2.6e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CDO73560.1 - 0.00058 19.7 0.1 0.00068 19.5 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 CDO73560.1 - 0.0086 15.8 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 PELOTA RNA binding domain bZIP_1 PF00170.16 CDO73560.1 - 0.18 11.7 0.6 0.43 10.5 0.1 1.8 2 0 0 2 2 2 0 bZIP transcription factor CBM_1 PF00734.13 CDO73561.1 - 3.7e-10 39.2 6.9 3.7e-10 39.2 4.8 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain DOMON PF03351.12 CDO73561.1 - 0.0055 16.6 0.0 0.0095 15.8 0.0 1.3 1 0 0 1 1 1 1 DOMON domain DUF2048 PF09752.4 CDO73561.1 - 0.19 10.5 0.1 0.48 9.2 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Herpes_capsid PF06112.6 CDO73561.1 - 0.57 10.2 3.8 0.84 9.6 2.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF1517 PF07466.6 CDO73561.1 - 8.7 5.2 5.9 15 4.4 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) gag-asp_proteas PF13975.1 CDO73562.1 - 0.034 13.9 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1713 PF08213.6 CDO73563.1 - 0.0007 19.1 10.7 0.001 18.6 7.4 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) RhoGEF PF00621.15 CDO73564.1 - 7.6e-14 51.9 0.1 1.1e-13 51.4 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF1804 PF08822.6 CDO73564.1 - 0.081 12.6 0.1 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) F-box-like PF12937.2 CDO73565.1 - 2.4e-06 27.1 1.0 1.2e-05 24.9 0.7 2.3 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 CDO73565.1 - 0.014 14.9 1.2 2.5 7.8 0.5 3.4 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box PF00646.28 CDO73565.1 - 0.11 12.2 2.1 1.6 8.5 0.9 2.7 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.1 CDO73565.1 - 0.26 11.0 2.7 30 4.4 0.1 3.5 3 1 1 4 4 4 0 Leucine rich repeat Glyco_transf_22 PF03901.12 CDO73566.1 - 1.9e-85 287.3 19.5 2.4e-85 287.0 13.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3835 PF12927.2 CDO73566.1 - 3.1e-08 34.4 0.2 3.1e-08 34.4 0.1 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3835) PMT_2 PF13231.1 CDO73566.1 - 0.0069 16.2 10.0 0.0069 16.2 6.9 2.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase FAM178 PF14816.1 CDO73566.1 - 0.9 8.1 2.2 0.61 8.7 0.5 1.4 1 1 0 1 1 1 0 Family of unknown function, FAM178 KH_1 PF00013.24 CDO73567.1 - 0.00015 21.3 2.0 0.00017 21.1 0.5 1.7 2 0 0 2 2 2 1 KH domain Prothymosin PF03247.9 CDO73567.1 - 0.014 15.5 0.9 0.023 14.8 0.6 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family F-box PF00646.28 CDO73568.1 - 3.8e-05 23.2 0.0 0.00011 21.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO73568.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 CDO73568.1 - 0.035 13.8 3.4 0.079 12.6 0.1 2.7 2 1 0 2 2 2 0 F-box-like domain Hemerythrin PF01814.18 CDO73569.1 - 4.7e-08 33.2 7.3 7.4e-08 32.6 5.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain VRR_NUC PF08774.6 CDO73570.1 - 1.4e-20 73.2 0.0 4e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain Rho_N PF07498.7 CDO73570.1 - 0.039 13.7 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain WD40 PF00400.27 CDO73572.1 - 1.1e-08 34.5 4.5 5.2e-05 22.9 0.3 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat CNH PF00780.17 CDO73572.1 - 0.15 11.4 0.0 0.45 9.8 0.0 1.8 1 1 0 2 2 2 0 CNH domain Glyoxal_oxid_N PF07250.6 CDO73573.1 - 2.2e-48 164.4 0.0 5.4e-48 163.1 0.0 1.6 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CDO73573.1 - 9.1e-21 73.7 0.0 2.8e-20 72.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) SKIP_SNW PF02731.10 CDO73574.1 - 1e-66 223.2 1.8 1e-66 223.2 1.2 2.4 2 0 0 2 2 2 1 SKIP/SNW domain Myc_N PF01056.13 CDO73574.1 - 0.11 11.6 5.5 0.23 10.5 3.8 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Spt5_N PF11942.3 CDO73574.1 - 6.9 7.3 24.8 0.35 11.5 7.1 3.4 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Tim54 PF11711.3 CDO73575.1 - 1.4e-73 247.7 3.2 4.5e-73 246.0 1.3 2.4 1 1 1 2 2 2 1 Inner membrane protein import complex subunit Tim54 RloB PF13707.1 CDO73575.1 - 0.0095 15.6 0.2 0.019 14.6 0.1 1.4 1 0 0 1 1 1 1 RloB-like protein Epimerase_Csub PF13950.1 CDO73575.1 - 0.22 11.5 1.1 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 UDP-glucose 4-epimerase C-term subunit Sec63 PF02889.11 CDO73576.1 - 3.5e-23 82.3 1.5 4.4e-22 78.7 0.1 2.2 1 1 1 2 2 2 2 Sec63 Brl domain Helicase_C PF00271.26 CDO73576.1 - 6.4e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CKS PF01111.14 CDO73577.1 - 8.5e-37 124.8 0.3 1.1e-36 124.5 0.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF3822 PF12864.2 CDO73577.1 - 0.027 13.6 0.1 0.037 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) DUF4358 PF14270.1 CDO73577.1 - 0.33 10.8 2.1 0.67 9.8 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Peptidase_M16 PF00675.15 CDO73578.1 - 1e-38 132.4 1.5 6.3e-38 129.8 0.1 2.6 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CDO73578.1 - 9.3e-24 84.1 0.0 7e-14 51.9 0.1 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF1104 PF06518.6 CDO73578.1 - 0.053 13.6 0.5 0.44 10.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) NblA PF04485.7 CDO73578.1 - 5.3 6.9 6.5 21 5.0 0.1 2.5 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA NMDAR2_C PF10565.4 CDO73579.1 - 0.028 13.1 0.0 0.041 12.5 0.0 1.2 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Rep_fac-A_C PF08646.5 CDO73580.1 - 5.4e-47 159.1 0.3 4.5e-44 149.6 0.0 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 CDO73580.1 - 2.5e-20 72.1 0.1 4.9e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 CDO73580.1 - 2.4e-15 56.1 0.1 1.2e-13 50.6 0.0 2.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 CDO73580.1 - 0.00038 20.4 0.0 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF223 DUF4539 PF15072.1 CDO73580.1 - 0.013 15.1 0.0 0.034 13.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) Prok-RING_1 PF14446.1 CDO73580.1 - 0.025 14.3 0.5 0.047 13.4 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.7 CDO73580.1 - 0.08 12.7 1.5 0.2 11.4 1.1 1.6 1 0 0 1 1 1 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.2 CDO73580.1 - 0.094 12.5 0.7 0.18 11.6 0.5 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_L37ae PF01780.14 CDO73580.1 - 0.095 12.5 0.6 0.26 11.1 0.4 1.7 1 0 0 1 1 1 0 Ribosomal L37ae protein family IDO PF01231.13 CDO73581.1 - 1.2e-96 323.7 0.0 1.5e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ECH_C PF13766.1 CDO73582.1 - 3.8e-32 110.8 0.5 8.5e-32 109.7 0.2 1.7 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CDO73582.1 - 1.1e-21 77.0 0.0 4.1e-21 75.2 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family DUF1822 PF08852.6 CDO73582.1 - 0.024 13.4 0.2 0.035 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) HEAT_2 PF13646.1 CDO73582.1 - 0.075 13.3 0.6 0.31 11.3 0.4 2.1 1 1 0 1 1 1 0 HEAT repeats CAP_GLY PF01302.20 CDO73583.1 - 3.3e-18 65.1 0.6 6.4e-18 64.2 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 CDO73583.1 - 3.9e-12 45.4 1.0 0.069 12.7 0.1 5.9 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO73583.1 - 1.9e-10 40.3 0.3 0.046 13.4 0.0 5.2 4 2 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CDO73583.1 - 6.3e-06 25.5 0.3 25 5.4 0.1 7.1 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_9 PF14580.1 CDO73583.1 - 0.0002 20.9 0.0 0.0015 18.1 0.0 2.3 2 1 1 3 3 3 1 Leucine-rich repeat LRR_7 PF13504.1 CDO73583.1 - 0.055 13.6 2.9 27 5.5 0.1 5.7 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 CDO73583.1 - 0.063 13.3 6.0 66 4.0 0.0 6.3 7 1 1 8 8 8 0 Leucine Rich repeat RRM_1 PF00076.17 CDO73584.1 - 3.1e-31 106.7 0.0 7.1e-18 64.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO73584.1 - 6.6e-25 86.8 0.0 5.3e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO73584.1 - 1.3e-16 60.1 0.0 7e-09 35.3 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CDO73584.1 - 6.1e-07 29.1 0.2 0.0062 16.2 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 CDO73584.1 - 6.9e-06 25.8 0.0 0.00068 19.4 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 CDO73584.1 - 0.00014 21.5 0.0 0.0079 15.9 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.10 CDO73584.1 - 0.017 14.7 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain Calcipressin PF04847.7 CDO73584.1 - 0.031 13.8 0.0 0.21 11.1 0.0 2.2 2 1 1 3 3 3 0 Calcipressin SET_assoc PF11767.3 CDO73584.1 - 0.17 11.2 0.1 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Aminotran_5 PF00266.14 CDO73585.1 - 5.4e-98 328.1 0.0 6.4e-98 327.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CDO73585.1 - 2.6e-09 36.6 0.1 3.7e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CDO73585.1 - 9.2e-05 20.8 0.0 0.00015 20.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CDO73585.1 - 0.00013 21.1 0.1 0.0019 17.3 0.1 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.14 CDO73585.1 - 0.055 13.3 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 B12 binding domain Glyco_hydro_6 PF01341.12 CDO73586.1 - 1.6e-112 375.8 3.2 1.9e-112 375.5 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 CDO73586.1 - 9.5e-15 53.9 11.5 2.1e-14 52.8 8.0 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain CHCH PF06747.8 CDO73586.1 - 0.14 12.0 0.4 11 6.0 0.1 2.4 2 0 0 2 2 2 0 CHCH domain MGC-24 PF05283.6 CDO73586.1 - 0.77 9.5 10.1 2.4 7.9 7.0 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF1681 PF07933.9 CDO73587.1 - 1.6e-48 164.2 0.0 1.9e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DEC-1_N PF04625.8 CDO73588.1 - 0.45 9.1 3.6 0.71 8.4 2.5 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NIF PF03031.13 CDO73589.1 - 1.4e-19 70.2 0.0 2.2e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CDO73589.1 - 0.11 12.6 0.1 1.5 9.0 0.0 2.6 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.16 CDO73590.1 - 4.9e-67 225.7 0.0 1.1e-63 214.7 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family NUDIX PF00293.23 CDO73591.1 - 6.4e-16 58.2 0.0 3.8e-15 55.7 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain COesterase PF00135.23 CDO73592.1 - 3.7e-64 217.3 0.0 4.8e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CDO73592.1 - 3e-13 49.8 0.1 4.7e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold CwfJ_C_1 PF04677.10 CDO73593.1 - 7.3e-30 103.1 0.0 1.7e-29 101.9 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CDO73593.1 - 3.9e-19 68.9 0.0 7.7e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 CDO73593.1 - 1.2e-08 34.2 9.3 0.0038 16.6 0.2 3.7 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC PF00098.18 CDO73593.1 - 0.017 15.0 5.6 0.34 10.9 0.0 3.4 3 0 0 3 3 3 0 Zinc knuckle eIF3g PF12353.3 CDO73593.1 - 0.12 12.2 0.6 0.97 9.3 0.2 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Apc15p PF05841.6 CDO73594.1 - 0.0013 19.4 0.7 0.0046 17.6 0.0 1.9 1 1 1 2 2 2 1 Apc15p protein ANAPC15 PF15243.1 CDO73594.1 - 1.3 9.0 25.8 3.1e+03 -1.7 17.9 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 Cwf_Cwc_15 PF04889.7 CDO73594.1 - 1.7 8.3 13.1 2.2 7.9 9.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Arginase PF00491.16 CDO73595.1 - 1.9e-74 250.4 0.0 2.4e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family Aminotran_1_2 PF00155.16 CDO73596.1 - 1.6e-27 96.4 0.0 6.3e-22 78.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CDO73596.1 - 0.0013 17.9 0.0 0.0025 17.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase MFS_1 PF07690.11 CDO73597.1 - 5.3e-34 117.4 27.3 8e-34 116.8 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Chitin_synth_2 PF03142.10 CDO73597.1 - 0.013 13.8 0.9 0.021 13.2 0.6 1.2 1 0 0 1 1 1 0 Chitin synthase Acyl-CoA_dh_1 PF00441.19 CDO73598.1 - 4.4e-43 146.9 0.3 1.1e-42 145.6 0.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CDO73598.1 - 5.6e-38 129.9 0.0 1e-37 129.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CDO73598.1 - 1.1e-17 63.2 0.0 2.4e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CDO73598.1 - 1.1e-15 58.0 0.0 1.1e-15 58.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CDO73598.1 - 0.035 14.4 0.0 0.096 12.9 0.0 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal HpaB_N PF11794.3 CDO73598.1 - 0.082 12.2 0.1 0.33 10.2 0.0 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Zn_clus PF00172.13 CDO73600.1 - 3.9e-10 39.4 15.3 3.9e-10 39.4 10.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.22 CDO73601.1 - 2.6e-15 55.4 5.9 4.9e-15 54.5 4.1 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 CDO73601.1 - 3.6e-05 23.7 0.0 6.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 CDO73601.1 - 0.00051 19.7 0.0 0.00093 18.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold HALZ PF02183.13 CDO73601.1 - 0.012 15.3 0.2 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper PAS_9 PF13426.1 CDO73601.1 - 0.014 15.7 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 PAS domain bZIP_2 PF07716.10 CDO73601.1 - 0.081 12.7 1.9 0.17 11.7 1.3 1.5 1 0 0 1 1 1 0 Basic region leucine zipper adh_short_C2 PF13561.1 CDO73602.1 - 1.2e-30 107.0 0.0 1.6e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO73602.1 - 6.2e-25 88.0 1.9 8.1e-25 87.6 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CDO73602.1 - 5.7e-12 45.6 0.0 1.6e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CDO73602.1 - 0.00098 18.1 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 CDO73602.1 - 0.0022 17.4 0.1 0.0098 15.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1805 PF08827.6 CDO73602.1 - 0.014 15.1 0.1 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Kinesin PF00225.18 CDO73603.1 - 1.3e-97 326.4 0.0 4.2e-56 190.0 0.0 5.0 5 0 0 5 5 5 2 Kinesin motor domain Reo_sigmaC PF04582.7 CDO73603.1 - 0.003 16.8 0.6 0.003 16.8 0.4 10.5 6 2 3 11 11 11 5 Reovirus sigma C capsid protein Fib_alpha PF08702.5 CDO73603.1 - 0.0048 17.0 1.9 0.0048 17.0 1.3 13.4 5 3 5 14 14 14 3 Fibrinogen alpha/beta chain family SlyX PF04102.7 CDO73603.1 - 0.0064 16.8 3.4 0.0064 16.8 2.3 16.5 14 6 6 21 21 21 3 SlyX Phlebovirus_G2 PF07245.6 CDO73603.1 - 0.19 9.9 0.0 0.32 9.2 0.0 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Acetyltransf_7 PF13508.1 CDO73604.1 - 1.3e-11 44.5 0.0 2.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO73604.1 - 2.3e-06 27.5 0.4 1.1e-05 25.3 0.3 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CDO73604.1 - 6e-06 26.3 0.0 2.3e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CDO73604.1 - 0.00018 21.3 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 CDO73604.1 - 0.00087 18.9 0.0 0.0023 17.6 0.0 1.7 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase FR47 PF08445.5 CDO73604.1 - 0.0065 16.1 0.0 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 CDO73604.1 - 0.062 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.27 CDO73605.1 - 1.9e-21 75.0 12.3 1.1e-07 31.4 0.1 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat Rax2 PF12768.2 CDO73605.1 - 0.00029 20.1 0.0 0.02 14.1 0.0 2.3 2 0 0 2 2 2 2 Cortical protein marker for cell polarity eIF2A PF08662.6 CDO73605.1 - 0.013 15.2 0.1 0.71 9.5 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.16 CDO73605.1 - 0.059 11.9 2.4 0.98 7.9 0.2 2.7 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region BTB PF00651.26 CDO73606.1 - 0.021 14.7 0.0 3 7.8 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain Pkinase PF00069.20 CDO73607.1 - 3e-37 128.2 0.0 4e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73607.1 - 1.3e-14 53.9 0.0 1.6e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO73607.1 - 7.9e-07 28.3 0.0 1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like PI3_PI4_kinase PF00454.22 CDO73608.1 - 2.9e-28 98.9 0.3 1.5e-27 96.6 0.2 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CDO73608.1 - 8.4e-22 77.2 0.0 2.5e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 CDO73608.1 - 0.14 11.1 0.1 0.26 10.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) K-box PF01486.12 CDO73608.1 - 0.16 11.7 0.1 0.42 10.4 0.1 1.7 1 0 0 1 1 1 0 K-box region RdRP PF05183.7 CDO73610.1 - 1.7e-126 423.2 0.0 4.8e-126 421.7 0.0 1.8 1 1 0 1 1 1 1 RNA dependent RNA polymerase Peptidase_M28 PF04389.12 CDO73611.1 - 1.9e-09 37.4 0.0 2.7e-09 36.9 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M28 Oxidored_FMN PF00724.15 CDO73612.1 - 1.4e-97 326.7 0.0 1.8e-97 326.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2408 PF10303.4 CDO73613.1 - 0.0088 16.1 0.8 0.015 15.3 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) DUF3829 PF12889.2 CDO73613.1 - 0.075 12.2 2.0 0.14 11.3 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) HORMA PF02301.13 CDO73614.1 - 3.9e-18 65.6 0.0 5.9e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 CDO73614.1 - 0.0043 16.7 14.7 0.0084 15.7 10.2 1.5 1 0 0 1 1 1 1 PHD-finger MarR PF01047.17 CDO73614.1 - 0.012 15.3 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 MarR family PFU PF09070.6 CDO73615.1 - 3.7e-43 146.2 0.0 8.4e-43 145.0 0.0 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 CDO73615.1 - 2.7e-30 103.1 14.3 3.9e-06 26.5 0.2 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat PUL PF08324.6 CDO73615.1 - 1.3e-21 76.5 0.0 2e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 CDO73615.1 - 0.0013 18.4 0.0 0.42 10.4 0.0 3.1 1 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Na_Ca_ex PF01699.19 CDO73616.1 - 2.7e-35 121.0 37.5 6e-25 87.4 6.9 3.8 2 1 1 3 3 3 3 Sodium/calcium exchanger protein AhpC-TSA_2 PF13911.1 CDO73617.1 - 7.9e-18 64.4 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 CDO73617.1 - 0.00044 19.9 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family His_Phos_1 PF00300.17 CDO73618.1 - 5e-23 81.9 1.8 2.4e-22 79.6 1.3 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Gtr1_RagA PF04670.7 CDO73619.1 - 4.1e-50 170.0 0.0 6.1e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DMRL_synthase PF00885.14 CDO73619.1 - 6.9e-45 152.2 0.1 1.8e-25 89.2 0.0 2.4 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase SRP40_C PF05022.7 CDO73620.1 - 3.8e-28 97.7 1.7 3.8e-28 97.7 1.2 2.5 2 0 0 2 2 2 1 SRP40, C-terminal domain vMSA PF00695.14 CDO73620.1 - 0.61 9.2 2.0 1.1 8.3 1.4 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Utp14 PF04615.8 CDO73620.1 - 4 5.4 59.3 5.9 4.9 41.1 1.3 1 0 0 1 1 1 0 Utp14 protein ATP_bind_3 PF01171.15 CDO73621.1 - 2.5e-39 134.6 0.0 4.4e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 PP-loop family YTH PF04146.10 CDO73622.1 - 8.7e-47 158.2 0.0 1.4e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Cryptochrome_C PF12546.3 CDO73622.1 - 3.5 8.3 13.7 0.036 14.7 1.6 3.1 3 0 0 3 3 3 0 Blue/Ultraviolet sensing protein C terminal WD40 PF00400.27 CDO73623.1 - 1.7e-75 246.4 7.1 5.9e-14 51.3 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CDO73623.1 - 1.2e-08 33.6 6.5 0.023 12.8 0.0 5.1 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CDO73623.1 - 1.2e-06 27.6 0.4 2 7.0 0.0 4.3 2 2 1 4 4 4 3 Nup133 N terminal like eIF2A PF08662.6 CDO73623.1 - 2.5e-05 24.0 0.0 0.021 14.5 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF1652 PF07865.6 CDO73623.1 - 0.02 14.4 0.0 15 5.3 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) LisH PF08513.6 CDO73623.1 - 0.058 13.1 0.4 0.098 12.4 0.3 1.4 1 0 0 1 1 1 0 LisH bZIP_2 PF07716.10 CDO73623.1 - 1.3 8.8 4.6 0.2 11.4 0.4 1.6 2 0 0 2 2 2 0 Basic region leucine zipper OPT PF03169.10 CDO73624.1 - 2.1e-151 505.4 48.0 2.4e-151 505.2 33.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein WD40 PF00400.27 CDO73625.1 - 0.0082 16.0 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2636 PF11120.3 CDO73625.1 - 0.0094 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2636) Transketolase_C PF02780.15 CDO73626.1 - 3.3e-25 88.4 0.0 2.8e-24 85.4 0.0 2.4 2 1 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 CDO73626.1 - 1.2e-24 86.7 1.2 3e-18 65.9 0.4 2.2 1 1 1 2 2 2 2 Transketolase, pyrimidine binding domain F-box PF00646.28 CDO73627.1 - 9e-06 25.2 0.3 0.00017 21.1 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CDO73627.1 - 0.025 14.2 1.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 0 F-box-like HSF_DNA-bind PF00447.12 CDO73628.1 - 4e-32 110.4 0.2 8e-32 109.4 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Filament PF00038.16 CDO73628.1 - 0.047 13.1 0.3 0.047 13.1 0.2 1.6 2 0 0 2 2 2 0 Intermediate filament protein POT1 PF02765.12 CDO73630.1 - 3.2e-10 40.0 0.0 7.1e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 TAP42 PF04177.7 CDO73631.1 - 8.1e-74 248.5 1.3 9.2e-74 248.4 0.9 1.0 1 0 0 1 1 1 1 TAP42-like family GMC_oxred_C PF05199.8 CDO73631.1 - 0.022 15.0 0.2 0.072 13.3 0.1 1.8 2 0 0 2 2 2 0 GMC oxidoreductase RuvA_C PF07499.8 CDO73631.1 - 0.55 10.4 4.4 0.46 10.6 0.6 2.4 2 0 0 2 2 2 0 RuvA, C-terminal domain Ras PF00071.17 CDO73632.1 - 1.7e-59 199.8 0.3 2.1e-59 199.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO73632.1 - 1.1e-21 77.4 0.0 2.3e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO73632.1 - 1.9e-15 56.5 0.1 2.4e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO73632.1 - 1.2e-07 31.0 0.2 1.5e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDO73632.1 - 2e-07 30.6 0.1 1.4e-06 27.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CDO73632.1 - 2e-06 27.1 0.1 3.4e-06 26.4 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CDO73632.1 - 8.5e-06 25.7 0.0 1.7e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDO73632.1 - 0.00011 21.5 0.0 0.031 13.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B CPT PF07931.7 CDO73632.1 - 0.0022 17.6 0.1 0.049 13.2 0.0 2.4 1 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Dynamin_N PF00350.18 CDO73632.1 - 0.0038 17.0 0.0 0.86 9.4 0.0 2.5 2 1 0 2 2 2 1 Dynamin family PduV-EutP PF10662.4 CDO73632.1 - 0.0095 15.4 0.6 0.089 12.2 0.4 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 CDO73632.1 - 0.035 13.7 0.0 0.061 13.0 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 CDO73632.1 - 0.052 13.2 0.2 5.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CDO73632.1 - 0.061 13.4 0.0 0.7 10.0 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CDO73632.1 - 0.088 12.7 0.4 0.21 11.4 0.1 1.9 2 1 0 2 2 2 0 AAA domain MTHFR PF02219.12 CDO73633.1 - 7.3e-107 356.7 0.0 9.7e-107 356.3 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Peptidase_S8 PF00082.17 CDO73634.1 - 3.9e-35 121.3 4.2 3.5e-34 118.2 0.4 2.3 1 1 1 2 2 2 2 Subtilase family P_proprotein PF01483.15 CDO73634.1 - 7.7e-30 102.5 0.6 1.4e-29 101.6 0.4 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain MCM PF00493.18 CDO73635.1 - 3.7e-136 453.2 0.1 6.3e-135 449.2 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 CDO73635.1 - 3.9e-28 98.3 0.0 1.8e-26 93.0 0.3 2.6 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CDO73635.1 - 9.3e-08 31.4 0.0 1e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CDO73635.1 - 3.9e-07 29.8 0.0 2.7e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 CDO73635.1 - 0.00034 20.9 1.3 0.0012 19.1 0.9 2.0 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CDO73635.1 - 0.035 13.7 0.0 0.13 11.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 CDO73636.1 - 5e-20 71.4 0.0 1.2e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 BAH domain DNA_methylase PF00145.12 CDO73636.1 - 0.004 16.3 0.1 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF77 PF01910.12 CDO73637.1 - 8.8e-20 70.1 0.0 7.9e-19 67.1 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function DUF77 Arm PF00514.18 CDO73638.1 - 1.1e-13 50.4 6.0 9.2e-09 34.8 0.1 5.3 4 1 1 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDO73638.1 - 1.2e-09 38.3 16.5 0.0037 17.5 0.1 7.6 2 2 5 7 7 6 4 HEAT repeats HEAT PF02985.17 CDO73638.1 - 4.7e-05 23.1 21.6 0.28 11.3 0.0 8.7 9 0 0 9 9 9 3 HEAT repeat DUF3361 PF11841.3 CDO73638.1 - 0.0054 16.4 0.2 0.036 13.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Adaptin_N PF01602.15 CDO73638.1 - 0.0074 14.6 11.5 0.027 12.8 0.8 5.2 3 1 3 6 6 6 2 Adaptin N terminal region CLASP_N PF12348.3 CDO73638.1 - 0.012 14.9 0.1 0.2 10.9 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal Proteasom_PSMB PF10508.4 CDO73638.1 - 0.031 12.5 0.2 0.031 12.5 0.1 2.8 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 CDO73638.1 - 0.046 13.6 0.0 2 8.3 0.0 2.9 3 0 0 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.1 CDO73638.1 - 0.057 13.9 23.7 0.11 13.0 0.0 7.5 7 2 2 9 9 9 0 HEAT-like repeat Ric8 PF10165.4 CDO73638.1 - 0.066 12.0 2.0 1.1 7.9 0.1 2.8 3 0 0 3 3 3 0 Guanine nucleotide exchange factor synembryn E1_dh PF00676.15 CDO73639.1 - 1.2e-111 372.1 0.0 1.5e-111 371.9 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CDO73639.1 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 CDO73639.1 - 0.0013 18.3 1.0 0.0028 17.2 0.7 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Sfi1 PF08457.5 CDO73639.1 - 0.027 12.8 0.0 0.043 12.2 0.0 1.2 1 0 0 1 1 1 0 Sfi1 spindle body protein Coa1 PF08695.5 CDO73640.1 - 7.3e-32 109.3 0.0 8.7e-32 109.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 COG6 PF06419.6 CDO73641.1 - 1.6e-125 419.6 0.2 7.1e-102 341.5 0.0 2.4 3 0 0 3 3 3 2 Conserved oligomeric complex COG6 HSF_DNA-bind PF00447.12 CDO73641.1 - 5.4e-26 90.7 0.3 1.5e-25 89.3 0.2 1.7 1 1 0 1 1 1 1 HSF-type DNA-binding Filament PF00038.16 CDO73641.1 - 0.32 10.4 3.5 4.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Intermediate filament protein Arrestin_C PF02752.17 CDO73642.1 - 3.7e-11 43.2 0.1 1.7e-10 41.1 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CDO73642.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CDO73642.1 - 0.036 13.5 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Arrestin_N terminal like APG9 PF04109.11 CDO73643.1 - 1.8e-165 550.3 0.5 2.3e-165 550.0 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF3808 PF10300.4 CDO73644.1 - 4.9e-61 206.7 0.1 1.2e-48 165.8 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_19 PF14559.1 CDO73644.1 - 1.7e-06 28.2 2.2 4.5e-05 23.7 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDO73644.1 - 1.9e-06 27.3 0.3 0.58 10.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CDO73644.1 - 5e-05 22.8 0.1 0.00071 19.1 0.1 2.5 2 0 0 2 2 2 1 TPR repeat Apc3 PF12895.2 CDO73644.1 - 0.00017 21.6 0.1 0.00055 20.0 0.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CDO73644.1 - 0.00018 22.0 2.5 0.021 15.5 0.0 4.2 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO73644.1 - 0.0047 16.6 0.6 4 7.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDO73644.1 - 0.013 15.3 0.6 0.59 10.1 0.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CDO73644.1 - 0.014 15.0 0.0 2.1 8.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CDO73644.1 - 0.028 15.0 6.9 20 6.1 0.0 4.7 3 2 3 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDO73644.1 - 0.041 14.3 1.1 21 5.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat CoaE PF01121.15 CDO73646.1 - 4.6e-08 32.6 0.2 6.3e-08 32.2 0.2 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase LSM14 PF12701.2 CDO73647.1 - 6.2e-26 90.0 0.9 9.7e-26 89.4 0.0 1.8 2 0 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.5 CDO73647.1 - 1.6e-12 47.8 1.5 1.6e-12 47.8 1.1 2.1 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 CDO73647.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain vMSA PF00695.14 CDO73647.1 - 3.9 6.5 6.9 5.4 6.1 4.8 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Tyr_Deacylase PF02580.11 CDO73648.1 - 4.2e-29 101.3 0.0 5.5e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.16 CDO73649.1 - 6.2e-41 140.1 0.0 7.3e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CDO73650.1 - 1.6e-42 141.8 21.5 1.6e-10 40.4 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 CDO73650.1 - 3.7e-13 48.9 1.4 3.7e-13 48.9 1.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDO73650.1 - 4.7e-11 42.0 0.6 4.7e-11 42.0 0.4 2.8 2 1 1 3 3 3 1 F-box domain Nup160 PF11715.3 CDO73650.1 - 5.7e-09 34.6 3.7 0.0097 14.0 0.0 5.1 4 1 1 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CDO73650.1 - 0.0021 17.5 1.2 0.64 9.4 0.2 2.6 2 0 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 CDO73650.1 - 0.061 12.0 0.1 7.2 5.2 0.0 3.3 3 1 1 4 4 4 0 Nup133 N terminal like PRANC PF09372.5 CDO73650.1 - 0.19 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Fungal_trans PF04082.13 CDO73651.1 - 2.8e-21 75.5 0.4 5.2e-21 74.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.7 CDO73652.1 - 1.3e-07 31.3 0.0 3.6e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO73652.1 - 7.7e-05 22.2 0.0 0.0004 19.9 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase E1-N PF14463.1 CDO73652.1 - 0.041 13.4 0.1 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 E1 N-terminal domain NAD_binding_10 PF13460.1 CDO73652.1 - 0.089 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 CDO73652.1 - 0.18 11.3 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PWWP PF00855.12 CDO73653.1 - 0.003 17.7 2.0 0.029 14.5 0.0 2.8 2 1 0 2 2 2 1 PWWP domain DUF4537 PF15057.1 CDO73653.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) GDA1_CD39 PF01150.12 CDO73654.1 - 1.7e-95 320.1 0.0 2.2e-88 296.6 0.0 2.0 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CDO73654.1 - 0.0065 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Radical_SAM PF04055.16 CDO73655.1 - 1.2e-14 54.8 0.4 1.5e-13 51.2 0.1 2.6 2 1 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CDO73655.1 - 1e-11 44.7 0.1 2.8e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CDO73655.1 - 0.0037 17.3 0.0 0.03 14.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO73655.1 - 0.061 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein DUF2404 PF10296.4 CDO73656.1 - 0.00042 20.3 0.0 0.006 16.6 0.0 2.6 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) DUF4654 PF15547.1 CDO73656.1 - 0.016 15.5 0.1 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4654) Nuc_sug_transp PF04142.10 CDO73657.1 - 2.4e-74 249.5 5.9 3.8e-74 248.8 4.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 CDO73657.1 - 1.2e-07 31.8 5.2 1.2e-07 31.8 3.6 3.0 2 2 1 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 CDO73657.1 - 1.6e-05 23.9 12.0 3.7e-05 22.8 8.3 1.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 CDO73657.1 - 3.4e-05 23.5 3.7 3.4e-05 23.5 2.6 3.4 3 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 CDO73657.1 - 0.00042 20.3 6.7 0.00042 20.3 4.6 2.9 2 2 0 2 2 2 2 EamA-like transporter family Mit_ribos_Mrp51 PF11709.3 CDO73658.1 - 1.2e-21 77.2 2.4 3.1e-21 75.9 0.9 2.1 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit FbpA PF05833.6 CDO73659.1 - 0.092 11.2 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) UPF1_Zn_bind PF09416.5 CDO73660.1 - 2.6e-70 234.8 2.5 2.6e-70 234.8 1.7 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 CDO73660.1 - 3.2e-59 199.6 0.0 5.5e-59 198.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDO73660.1 - 3.6e-55 187.1 1.8 5.5e-55 186.5 1.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO73660.1 - 2e-14 53.0 0.9 4.2e-14 52.0 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CDO73660.1 - 6e-13 48.8 0.1 9.3e-12 44.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CDO73660.1 - 3.5e-08 33.5 0.0 6.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 CDO73660.1 - 5.3e-07 29.3 0.0 0.038 13.5 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 CDO73660.1 - 1.6e-06 27.3 0.0 2.4e-05 23.5 0.0 2.6 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 CDO73660.1 - 0.00043 19.9 0.1 0.00091 18.9 0.0 1.6 1 0 0 1 1 1 1 Helicase Ribosomal_S13_N PF08069.7 CDO73660.1 - 0.00056 19.6 0.0 0.0017 18.1 0.0 1.8 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain UvrD-helicase PF00580.16 CDO73660.1 - 0.00065 19.0 0.1 0.01 15.1 0.0 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 CDO73660.1 - 0.017 14.0 0.1 0.61 8.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_25 PF13481.1 CDO73660.1 - 0.019 14.3 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 CDO73660.1 - 0.021 14.3 0.4 0.056 12.9 0.3 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase SRP54 PF00448.17 CDO73660.1 - 0.031 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 CDO73660.1 - 0.039 13.9 0.1 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CDO73660.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Ribosomal_S27e PF01667.12 CDO73660.1 - 0.053 13.0 0.6 0.17 11.4 0.4 1.8 1 0 0 1 1 1 0 Ribosomal protein S27 KaiC PF06745.8 CDO73660.1 - 0.064 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 CDO73660.1 - 0.069 12.3 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_10 PF12846.2 CDO73660.1 - 0.077 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 CDO73660.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Lipase_GDSL PF00657.17 CDO73661.1 - 3.6e-13 49.8 0.3 7.1e-13 48.9 0.2 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CDO73661.1 - 1.5e-05 25.1 0.1 2.3e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Adap_comp_sub PF00928.16 CDO73662.1 - 1.2e-85 286.7 0.0 1.5e-85 286.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CDO73662.1 - 9e-08 31.9 1.5 1.6e-07 31.1 1.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CENP-C_C PF11699.3 CDO73663.1 - 9.9e-23 79.9 3.3 1.7e-18 66.3 0.5 2.3 2 0 0 2 2 2 2 Mif2/CENP-C like Cupin_2 PF07883.6 CDO73663.1 - 0.0078 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain PAP_assoc PF03828.14 CDO73664.1 - 7.9e-17 60.9 0.1 1.8e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CDO73664.1 - 1.9e-07 31.3 0.0 3.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain SAPS PF04499.10 CDO73666.1 - 3.1e-127 425.1 0.0 5.1e-127 424.4 0.0 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein tRNA_Me_trans PF03054.11 CDO73666.1 - 5.3e-78 262.0 0.0 7.8e-78 261.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase FAA_hydrolase PF01557.13 CDO73667.1 - 1.5e-57 194.5 0.0 1.9e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family TPP_enzyme_N PF02776.13 CDO73669.1 - 5.1e-44 149.7 0.5 1.7e-43 148.1 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CDO73669.1 - 5.4e-44 149.4 0.2 1.3e-43 148.1 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CDO73669.1 - 3.3e-22 78.7 0.3 1.6e-21 76.5 0.1 2.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain WD40 PF00400.27 CDO73671.1 - 1e-06 28.3 1.9 0.014 15.2 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ADH_zinc_N PF00107.21 CDO73672.1 - 1.2e-18 66.9 1.5 2.1e-18 66.0 1.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO73672.1 - 3.6e-07 31.1 0.7 9.5e-07 29.7 0.5 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.5 CDO73672.1 - 0.043 13.8 1.5 0.11 12.5 0.2 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Choline_transpo PF04515.7 CDO73673.1 - 1.5e-05 23.9 18.6 0.00018 20.3 7.4 3.4 1 1 1 2 2 2 2 Plasma-membrane choline transporter BLVR PF06375.6 CDO73674.1 - 0.01 15.6 6.0 0.024 14.4 4.1 1.6 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) PAT1 PF09770.4 CDO73674.1 - 0.28 9.3 0.0 0.28 9.3 0.0 2.8 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 FLO_LFY PF01698.11 CDO73674.1 - 0.67 8.7 6.3 1.1 8.0 4.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein G-alpha PF00503.15 CDO73675.1 - 2e-79 267.1 0.1 7.3e-79 265.2 0.1 1.6 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CDO73675.1 - 0.0013 18.0 0.0 0.024 13.8 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 CDO73675.1 - 0.085 12.3 0.0 0.41 10.1 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein La PF05383.12 CDO73676.1 - 1.5e-19 69.4 0.0 2.8e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 La domain adh_short PF00106.20 CDO73677.1 - 1.2e-08 35.0 0.1 1.2e-08 35.0 0.1 2.0 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 CDO73677.1 - 2.4e-05 24.0 0.2 3.8e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 CDO73677.1 - 0.00094 19.2 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 CDO73677.1 - 0.0018 18.3 1.4 0.017 15.1 0.7 2.6 2 1 0 2 2 2 1 NADH(P)-binding ADH_zinc_N PF00107.21 CDO73677.1 - 0.033 13.7 0.1 0.072 12.6 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short_C2 PF13561.1 CDO73677.1 - 0.034 13.9 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase ATHILA PF03078.10 CDO73677.1 - 0.066 11.7 0.0 0.095 11.2 0.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family NAD_binding_7 PF13241.1 CDO73677.1 - 0.089 13.0 0.0 0.57 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Epimerase PF01370.16 CDO73677.1 - 0.11 11.8 0.1 0.22 10.9 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 CDO73677.1 - 0.15 11.7 0.1 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAD PF03068.10 CDO73678.1 - 0.18 10.2 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) AdoHcyase PF05221.12 CDO73679.1 - 1.7e-141 469.8 0.0 1.9e-141 469.6 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CDO73679.1 - 3e-86 287.2 0.9 4.4e-86 286.7 0.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CDO73679.1 - 1.1e-09 37.7 0.0 2.2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CDO73679.1 - 1.8e-05 24.2 0.2 2.9e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CDO73679.1 - 0.001 19.0 0.1 0.0024 17.8 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CDO73679.1 - 0.0037 16.8 0.1 0.0061 16.1 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 CDO73679.1 - 0.024 14.7 0.4 0.053 13.6 0.3 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CDO73679.1 - 0.057 13.6 0.3 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GAS PF13851.1 CDO73680.1 - 0.073 12.2 1.4 0.1 11.7 1.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PspB PF06667.7 CDO73680.1 - 0.15 12.0 1.2 0.26 11.2 0.8 1.3 1 0 0 1 1 1 0 Phage shock protein B APG6 PF04111.7 CDO73680.1 - 0.18 10.7 0.2 0.26 10.3 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 GST_N_3 PF13417.1 CDO73681.1 - 2.3e-07 30.9 0.0 4.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO73681.1 - 1.4e-05 25.1 0.0 3.1e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CDO73681.1 - 0.00023 21.0 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO73681.1 - 0.00055 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CDO73681.1 - 0.0077 16.2 0.1 0.05 13.5 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CDO73681.1 - 0.019 15.4 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Leu_zip PF15294.1 CDO73682.1 - 0.027 13.5 2.8 0.031 13.3 1.6 1.3 1 1 0 1 1 1 0 Leucine zipper DUF812 PF05667.6 CDO73682.1 - 0.039 12.4 5.1 0.052 12.0 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Img2 PF05046.9 CDO73682.1 - 0.087 13.0 0.1 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Apolipoprotein PF01442.13 CDO73682.1 - 0.2 11.1 6.0 0.41 10.1 3.8 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain IBR PF01485.16 CDO73683.1 - 1.7e-14 53.4 28.8 4.3e-08 32.9 4.3 3.6 3 0 0 3 3 3 2 IBR domain RRM_1 PF00076.17 CDO73683.1 - 2.2e-08 33.5 0.0 0.00043 19.8 0.0 4.2 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO73683.1 - 4.4e-06 26.5 0.0 0.057 13.4 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 CDO73683.1 - 7.4e-06 25.5 2.1 7.4e-06 25.5 1.4 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO73683.1 - 1.7e-05 24.5 3.1 1.7e-05 24.5 2.2 4.2 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 CDO73683.1 - 2.1e-05 24.1 1.5 2.1e-05 24.1 1.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CDO73683.1 - 2.3e-05 24.3 4.2 2.3e-05 24.3 2.9 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDO73683.1 - 5.7e-05 22.8 3.9 5.7e-05 22.8 2.7 3.8 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CDO73683.1 - 0.00095 18.7 2.7 0.00095 18.7 1.8 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO73683.1 - 0.0014 18.2 3.7 0.0014 18.2 2.6 3.7 3 1 0 3 3 3 1 zinc-RING finger domain RRF PF01765.14 CDO73685.1 - 1e-19 70.5 0.3 1e-19 70.5 0.2 2.6 1 1 2 3 3 3 1 Ribosome recycling factor RNA_bind_2 PF10133.4 CDO73685.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted RNA-binding protein Mito_carr PF00153.22 CDO73686.1 - 2.5e-23 81.6 0.2 9.7e-22 76.5 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Glyco_hydro_16 PF00722.16 CDO73688.1 - 3.4e-07 29.7 0.0 7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Acyl-CoA_dh_1 PF00441.19 CDO73690.1 - 2.7e-13 50.2 3.7 7.8e-13 48.7 1.2 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 CDO73690.1 - 3.1e-05 24.2 0.6 6.9e-05 23.1 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CDO73690.1 - 0.016 14.6 0.1 0.12 11.9 0.1 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain DUF2611 PF11022.3 CDO73692.1 - 3.6e-15 55.8 2.6 5.3e-15 55.2 1.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) TPD52 PF04201.10 CDO73693.1 - 0.015 15.0 2.9 1.9 8.1 0.2 2.6 2 0 0 2 2 2 0 Tumour protein D52 family Git3 PF11710.3 CDO73695.1 - 4.2e-08 32.9 4.2 8.3e-08 32.0 2.9 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 CDO73695.1 - 2e-05 23.6 2.3 3.1e-05 23.0 1.6 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor ADH_N PF08240.7 CDO73696.1 - 6e-25 87.1 1.5 6e-25 87.1 1.0 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO73696.1 - 1.1e-22 79.9 1.8 1.1e-22 79.9 1.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO73696.1 - 5.3e-09 37.0 0.6 1.8e-08 35.3 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CDO73696.1 - 0.00012 21.6 1.0 0.004 16.7 0.2 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.7 CDO73696.1 - 0.0075 16.7 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ufm1 PF03671.9 CDO73696.1 - 0.025 14.2 0.2 0.13 12.0 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin fold modifier 1 protein Ubie_methyltran PF01209.13 CDO73696.1 - 0.06 12.4 0.2 0.12 11.4 0.1 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CDO73696.1 - 0.12 12.9 0.1 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CoA_binding PF02629.14 CDO73696.1 - 0.27 11.7 2.7 1.3 9.5 0.3 2.5 2 0 0 2 2 2 0 CoA binding domain G-alpha PF00503.15 CDO73698.1 - 8.1e-114 380.3 0.0 2.9e-113 378.4 0.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit FA_desaturase PF00487.19 CDO73699.1 - 1.5e-16 60.6 21.6 1.5e-16 60.6 14.9 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 CDO73699.1 - 7.4e-15 54.5 0.0 1.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_C48 PF02902.14 CDO73700.1 - 2.6e-05 23.9 0.0 7.6e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Asp_protease_2 PF13650.1 CDO73702.1 - 0.00049 20.5 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.21 CDO73703.1 - 7.8e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF1330 PF07045.6 CDO73704.1 - 0.038 13.8 0.4 5 7.0 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1330) PSD4 PF07631.6 CDO73705.1 - 4.2e-05 23.9 0.4 0.25 11.7 0.1 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF1592) LRV PF01816.12 CDO73705.1 - 0.00071 19.5 1.1 2.5 8.4 0.0 3.6 2 0 0 2 2 2 2 Leucine rich repeat variant TusA PF01206.12 CDO73705.1 - 0.0016 17.9 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 2 Sulfurtransferase TusA Mac PF12464.3 CDO73705.1 - 0.011 15.7 0.1 8.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Maltose acetyltransferase GSHPx PF00255.14 CDO73706.1 - 2.1e-38 130.0 0.1 5.1e-37 125.5 0.1 2.1 1 1 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CDO73706.1 - 2.2e-06 27.3 0.0 6.7e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CDO73706.1 - 0.00055 19.5 0.0 0.0017 17.9 0.0 1.7 1 1 0 1 1 1 1 Redoxin Asp PF00026.18 CDO73707.1 - 2.7e-36 125.4 0.0 2.6e-28 99.2 0.2 2.2 1 1 1 2 2 2 2 Eukaryotic aspartyl protease UBN2_2 PF14227.1 CDO73707.1 - 3.1e-17 62.2 0.0 6.4e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO73707.1 - 1.6e-12 47.2 0.0 2.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TAXi_N PF14543.1 CDO73707.1 - 8.4e-09 35.5 0.5 2.1e-08 34.2 0.4 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal 3-alpha PF03475.9 CDO73707.1 - 0.16 11.7 0.1 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 3-alpha domain Metallophos PF00149.23 CDO73708.1 - 1.7e-07 30.8 0.6 3.2e-07 29.9 0.4 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDO73708.1 - 0.00068 19.4 0.0 0.001 18.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CAF-1_p150 PF11600.3 CDO73709.1 - 0.0039 16.5 21.3 0.008 15.5 14.8 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal GFO_IDH_MocA PF01408.17 CDO73710.1 - 2.2e-25 89.4 0.0 3.6e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 CDO73710.1 - 0.0019 18.5 0.0 0.007 16.6 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 CDO73710.1 - 0.063 13.8 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Abhydrolase_6 PF12697.2 CDO73711.1 - 2.9e-20 73.1 0.9 3.8e-20 72.7 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO73711.1 - 6.6e-15 55.1 0.0 9.7e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO73711.1 - 2.1e-11 43.4 0.0 6.2e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CDO73711.1 - 9.5e-07 28.5 0.0 0.00043 19.9 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 CDO73711.1 - 4.6e-06 25.3 0.7 0.049 12.1 0.3 3.0 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 CDO73711.1 - 0.00059 19.4 0.0 0.002 17.7 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDO73711.1 - 0.0024 17.1 0.1 0.15 11.2 0.0 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 CDO73711.1 - 0.011 14.9 0.0 0.053 12.8 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF155 PF02582.9 CDO73712.1 - 2.9e-42 144.5 0.0 4.2e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SNF5 PF04855.7 CDO73713.1 - 8.2e-60 202.2 0.1 2e-59 201.0 0.1 1.6 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 RNase_HII PF01351.13 CDO73713.1 - 3.2e-44 150.9 0.0 1.8e-36 125.6 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease HII SART-1 PF03343.8 CDO73714.1 - 9.6e-124 413.9 54.4 9.6e-124 413.9 37.7 2.0 2 0 0 2 2 2 2 SART-1 family MIF4G PF02854.14 CDO73715.1 - 3.5e-23 82.1 1.2 6.5e-23 81.2 0.3 1.9 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CDO73715.1 - 3.7e-16 58.8 0.2 1e-06 28.4 0.0 3.2 3 0 0 3 3 3 2 MA3 domain RRN3 PF05327.6 CDO73715.1 - 0.0067 14.6 2.2 0.014 13.5 1.6 1.4 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 CDO73715.1 - 6.5 5.0 36.3 0.0035 15.8 13.3 2.2 2 0 0 2 2 2 0 Daxx Family Methyltransf_18 PF12847.2 CDO73716.1 - 2.1e-15 57.2 0.0 3.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO73716.1 - 2.4e-10 40.2 0.0 1.3e-09 37.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO73716.1 - 5e-08 32.9 0.0 1e-07 32.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO73716.1 - 1.9e-05 25.0 0.1 0.007 16.8 0.1 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO73716.1 - 3.9e-05 23.9 0.0 9.6e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO73716.1 - 4.7e-05 23.7 0.0 0.00021 21.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO73716.1 - 7.3e-05 22.5 0.0 0.00019 21.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CDO73716.1 - 0.0028 17.3 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDO73716.1 - 0.015 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 CDO73716.1 - 0.038 13.0 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 CDO73716.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AAA_12 PF13087.1 CDO73717.1 - 1.6e-34 119.0 0.0 4e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDO73717.1 - 1.3e-22 80.5 1.0 2.8e-14 53.2 0.1 2.4 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CDO73717.1 - 1.1e-11 44.3 0.0 3.2e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CDO73717.1 - 1.7e-11 44.0 0.1 7.4e-11 41.9 0.0 2.2 2 1 0 2 2 1 1 AAA domain Helicase_RecD PF05127.9 CDO73717.1 - 1.6e-05 24.6 0.2 4.9e-05 23.0 0.0 1.9 2 1 0 2 2 1 1 Helicase AAA_16 PF13191.1 CDO73717.1 - 5.3e-05 23.2 0.2 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 CDO73717.1 - 0.00051 19.2 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 KaiC ResIII PF04851.10 CDO73717.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 CDO73717.1 - 0.00098 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.4 CDO73717.1 - 0.0016 17.4 0.1 0.045 12.7 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 CDO73717.1 - 0.0049 16.3 0.5 0.016 14.7 0.3 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CDO73717.1 - 0.0051 16.9 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CDO73717.1 - 0.0052 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ArgK PF03308.11 CDO73717.1 - 0.018 13.8 0.1 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 CDO73717.1 - 0.03 14.5 0.1 0.099 12.8 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CDO73717.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Viral_helicase1 PF01443.13 CDO73717.1 - 0.037 13.5 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CDO73717.1 - 0.037 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 CDO73717.1 - 0.04 13.3 0.1 0.085 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CDO73717.1 - 0.073 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CDO73717.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CDO73717.1 - 0.13 12.5 0.0 0.42 10.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain MobB PF03205.9 CDO73717.1 - 0.15 11.7 0.7 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CDO73717.1 - 0.23 12.3 1.3 0.68 10.7 0.5 2.2 2 0 0 2 2 1 0 AAA domain Carn_acyltransf PF00755.15 CDO73718.1 - 2.9e-94 316.2 0.0 6e-94 315.2 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1767 PF08585.7 CDO73719.1 - 8.3e-13 48.4 0.0 2.3e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1767) DEC-1_N PF04625.8 CDO73719.1 - 3 6.4 12.0 5 5.7 8.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DnaJ PF00226.26 CDO73720.1 - 9.4e-19 66.9 2.1 1.3e-17 63.2 0.6 2.6 2 0 0 2 2 2 1 DnaJ domain DUF2040 PF09745.4 CDO73720.1 - 0.1 12.4 12.7 0.25 11.1 8.9 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) YABBY PF04690.8 CDO73720.1 - 0.31 11.2 2.1 0.44 10.7 0.1 2.1 1 1 1 2 2 2 0 YABBY protein CtaG_Cox11 PF04442.9 CDO73721.1 - 5.4e-57 191.8 0.0 6.7e-57 191.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 TPR_19 PF14559.1 CDO73722.1 - 1.1e-12 48.0 6.5 1.5e-05 25.2 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDO73722.1 - 4.9e-11 42.9 1.1 2.1e-05 25.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CDO73722.1 - 3.9e-08 32.8 0.1 0.029 14.0 0.0 3.8 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CDO73722.1 - 4.8e-08 32.3 1.2 0.54 10.3 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO73722.1 - 1.2e-07 31.7 6.4 0.18 12.5 0.1 6.1 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDO73722.1 - 1.7e-06 27.3 0.8 4.2 7.1 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDO73722.1 - 8e-06 25.6 0.0 0.16 12.2 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDO73722.1 - 5.1e-05 23.1 0.8 0.15 12.0 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDO73722.1 - 0.0054 16.5 0.3 0.26 11.1 0.0 2.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 CDO73722.1 - 0.01 14.9 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDO73722.1 - 0.015 15.6 3.7 11 6.7 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 CDO73722.1 - 0.032 14.0 0.0 32 4.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 CDO73722.1 - 0.31 11.5 2.1 9.4 7.0 0.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 CDO73722.1 - 0.37 10.9 2.8 14 5.8 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CDO73722.1 - 1.6 8.6 8.0 17 5.3 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CDO73724.1 - 2.6e-32 111.2 1.7 4.6e-32 110.4 1.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 CDO73724.1 - 3.9e-13 49.1 0.0 2.3e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73724.1 - 2.1e-05 23.7 0.0 3.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 CDO73724.1 - 6.4e-05 22.7 0.0 0.00024 20.9 0.0 2.0 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 LsmAD PF06741.8 CDO73725.1 - 1.1e-22 79.8 1.4 1.4e-22 79.5 0.1 1.8 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 CDO73725.1 - 0.00086 19.1 0.2 0.002 18.0 0.1 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Phage_integrase PF00589.17 CDO73727.1 - 0.0089 15.7 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family DUF2272 PF10030.4 CDO73728.1 - 0.041 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) DUF1944 PF09175.5 CDO73729.1 - 0.19 11.3 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) DIOX_N PF14226.1 CDO73730.1 - 1.9e-24 86.4 0.1 3e-24 85.7 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO73730.1 - 6.3e-18 64.9 0.0 1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Snf7 PF03357.16 CDO73731.1 - 1.7e-42 144.6 11.1 2.9e-42 143.9 7.7 1.2 1 0 0 1 1 1 1 Snf7 DUF1569 PF07606.6 CDO73731.1 - 0.01 15.7 0.5 0.022 14.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) NPV_P10 PF05531.7 CDO73731.1 - 0.12 12.6 1.1 0.37 11.0 0.2 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 CDO73731.1 - 0.18 11.7 3.4 6.4 6.7 0.0 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NuA4 PF09340.5 CDO73731.1 - 0.2 11.3 2.1 0.29 10.7 0.3 2.2 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 TMF_TATA_bd PF12325.3 CDO73731.1 - 1.2 8.9 14.2 0.88 9.3 0.1 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding FlxA PF14282.1 CDO73731.1 - 1.7 8.5 7.7 0.86 9.5 2.4 2.3 1 1 2 3 3 3 0 FlxA-like protein Mnd1 PF03962.10 CDO73731.1 - 2.1 7.9 10.7 8 6.0 7.4 1.9 1 1 0 1 1 1 0 Mnd1 family Prefoldin_2 PF01920.15 CDO73731.1 - 2.1 8.1 13.3 7 6.4 0.1 3.6 2 2 0 3 3 3 0 Prefoldin subunit Aldedh PF00171.17 CDO73732.1 - 1.1e-146 488.8 0.0 1.9e-146 488.0 0.0 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_1 PF00561.15 CDO73732.1 - 8.8e-16 58.1 0.1 7.4e-13 48.5 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDO73732.1 - 3.5e-10 40.1 1.0 6.4e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family LuxC PF05893.9 CDO73732.1 - 9.5e-05 21.2 0.0 0.00016 20.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Esterase PF00756.15 CDO73732.1 - 0.0019 17.7 0.1 0.0032 16.9 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CDO73732.1 - 0.0053 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Asp_decarbox PF02261.11 CDO73732.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Aspartate decarboxylase SR-25 PF10500.4 CDO73732.1 - 2.8 7.3 6.1 4.6 6.6 4.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Snf7 PF03357.16 CDO73734.1 - 1.7e-14 53.6 10.4 2.8e-14 52.8 7.2 1.3 1 0 0 1 1 1 1 Snf7 DUF244 PF03112.9 CDO73734.1 - 0.8 9.2 4.6 0.78 9.2 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF DUF1053 PF06327.9 CDO73734.1 - 0.95 9.8 4.5 0.46 10.8 0.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) DUF724 PF05266.9 CDO73734.1 - 2.5 7.7 8.4 0.27 10.8 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2951 PF11166.3 CDO73734.1 - 3.2 7.6 7.0 12 5.8 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) DUF4407 PF14362.1 CDO73734.1 - 8.8 5.1 10.3 1.3 7.8 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cupin_8 PF13621.1 CDO73735.1 - 1.4e-52 178.7 0.0 1.7e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CDO73735.1 - 1e-06 28.9 0.0 3.5e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 CDO73735.1 - 0.016 14.6 0.1 0.15 11.5 0.1 2.3 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.7 CDO73735.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein ACT_7 PF13840.1 CDO73736.1 - 3.4e-14 52.1 0.2 1.4e-07 30.8 0.0 3.3 3 0 0 3 3 3 2 ACT domain ACT PF01842.20 CDO73736.1 - 0.078 12.4 0.7 30 4.2 0.0 3.7 3 1 1 4 4 4 0 ACT domain SKN1 PF03935.10 CDO73737.1 - 2.1e-190 633.1 1.3 2.4e-190 632.9 0.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Pex14_N PF04695.8 CDO73738.1 - 2.5e-10 40.5 0.0 2.5e-10 40.5 0.0 3.7 3 1 1 4 4 4 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M28 PF04389.12 CDO73739.1 - 8.7e-16 58.1 0.0 2.7e-15 56.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 CDO73739.1 - 3.4e-14 52.4 0.0 1.6e-13 50.2 0.0 2.1 3 0 0 3 3 3 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CDO73739.1 - 1.5e-07 30.9 0.1 4.5e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 CDO73739.1 - 0.00014 21.1 0.0 0.00069 18.9 0.0 1.9 2 0 0 2 2 2 1 Nicastrin FMN_dh PF01070.13 CDO73740.1 - 3.1e-102 342.0 0.0 4e-102 341.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 CDO73740.1 - 9.1e-06 24.7 0.7 2.7e-05 23.2 0.2 1.9 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 CDO73740.1 - 0.0002 20.4 0.2 0.0003 19.8 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CDO73740.1 - 0.002 17.3 0.8 0.0032 16.6 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 CDO73740.1 - 0.012 14.6 1.4 0.14 11.1 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 CDO73740.1 - 0.013 14.7 0.1 0.069 12.4 0.1 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.16 CDO73740.1 - 0.12 11.2 0.2 0.3 10.0 0.0 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase HALZ PF02183.13 CDO73742.1 - 0.0042 16.7 2.9 0.0042 16.7 2.0 1.9 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF2205 PF10224.4 CDO73742.1 - 0.025 14.1 1.3 0.092 12.3 0.1 2.3 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF4381 PF14316.1 CDO73743.1 - 0.091 12.8 0.3 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) GTP_cyclohydro2 PF00925.15 CDO73744.1 - 9.4e-65 216.9 0.0 5.8e-59 198.1 0.0 2.3 2 0 0 2 2 2 2 GTP cyclohydrolase II Vps5 PF09325.5 CDO73745.1 - 2.1e-18 66.4 1.2 2.7e-18 66.0 0.8 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CDO73745.1 - 5.6e-05 22.9 0.5 0.0002 21.1 0.0 2.1 2 0 0 2 2 2 1 PX domain Metal_resist PF13801.1 CDO73745.1 - 0.28 11.1 10.6 1.4 8.9 3.0 2.9 2 1 0 2 2 2 0 Heavy-metal resistance TPR_8 PF13181.1 CDO73745.1 - 0.6 10.0 2.7 25 4.9 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4200 PF13863.1 CDO73745.1 - 4.1 7.3 9.3 1 9.3 3.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Iso_dh PF00180.15 CDO73746.1 - 4e-123 410.7 0.0 5.2e-123 410.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_M24 PF00557.19 CDO73746.1 - 2.7e-13 49.9 0.0 4.8e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 NOB1_Zn_bind PF08772.6 CDO73747.1 - 1.7e-27 95.0 0.4 2.9e-27 94.2 0.3 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 CDO73747.1 - 1.3 8.2 6.0 2.9 7.2 4.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Cwf_Cwc_15 PF04889.7 CDO73747.1 - 8 6.1 16.1 0.49 10.0 6.7 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein P21-Arc PF04062.9 CDO73748.1 - 9.4e-79 263.2 0.0 1.1e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Sld5 PF05916.6 CDO73750.1 - 7e-18 64.9 0.2 1e-17 64.3 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein FAM150 PF15129.1 CDO73750.1 - 0.028 14.3 0.0 0.095 12.5 0.0 1.8 2 0 0 2 2 2 0 FAM150 family DUF3635 PF12330.3 CDO73751.1 - 6.3e-19 67.8 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Herpes_gE PF02480.11 CDO73753.1 - 0.079 11.2 0.1 0.12 10.5 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CDO73753.1 - 0.15 12.4 0.1 0.28 11.6 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 CDO73753.1 - 2.2 7.9 6.7 0.24 10.9 1.3 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 CDO73754.1 - 0.019 14.2 0.1 0.019 14.2 0.1 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF1049 PF06305.6 CDO73754.1 - 0.21 11.0 0.4 0.36 10.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) RF-1 PF00472.15 CDO73755.1 - 8.7e-22 77.0 0.1 2.6e-21 75.5 0.0 1.8 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 CDO73755.1 - 2.4e-20 72.3 0.3 7.5e-20 70.7 0.0 1.9 1 1 1 2 2 2 1 PCRF domain PP2C PF00481.16 CDO73756.1 - 7e-16 58.3 0.0 1.5e-14 54.0 0.0 2.6 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 CDO73756.1 - 0.0005 19.5 0.0 0.32 10.3 0.0 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C DUF2914 PF11141.3 CDO73756.1 - 0.58 9.7 4.5 0.44 10.1 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) UCH PF00443.24 CDO73757.1 - 1.4e-52 178.4 0.0 2.1e-52 177.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDO73757.1 - 2e-18 66.8 0.0 3.6e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CDO73757.1 - 0.003 16.8 0.4 0.036 13.3 0.3 2.6 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase IFT57 PF10498.4 CDO73757.1 - 0.11 11.2 0.4 0.16 10.6 0.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Hormone_5 PF00184.12 CDO73757.1 - 5.9 7.4 7.1 0.63 10.6 1.7 1.7 2 0 0 2 2 2 0 Neurohypophysial hormones, C-terminal Domain zf-C2H2_4 PF13894.1 CDO73758.1 - 4.8e-12 45.3 16.0 0.0011 19.1 0.2 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO73758.1 - 1.7e-06 28.0 24.9 0.0023 18.1 1.1 4.9 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CDO73758.1 - 0.0042 17.3 0.1 0.0042 17.3 0.1 3.9 5 1 0 5 5 3 2 Zinc-finger double domain zf-Di19 PF05605.7 CDO73758.1 - 0.0043 17.1 4.7 0.093 12.8 0.2 2.6 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CDO73758.1 - 0.0075 16.3 5.0 1.2 9.3 0.5 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CDO73758.1 - 0.028 14.6 2.1 7.5 6.9 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 CDO73758.1 - 0.068 13.4 6.7 0.036 14.3 2.3 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain PX PF00787.19 CDO73758.1 - 0.069 12.9 0.3 0.17 11.7 0.2 1.7 2 0 0 2 2 2 0 PX domain zf-C2HC_2 PF13913.1 CDO73758.1 - 0.078 12.6 6.1 0.69 9.6 1.0 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 CDO73758.1 - 1.6 8.8 5.3 5.3 7.2 0.1 2.9 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 CDO73758.1 - 4 7.2 9.1 4.3 7.1 0.7 3.2 2 1 1 3 3 3 0 BED zinc finger F-box-like PF12937.2 CDO73759.1 - 0.00021 20.9 0.3 0.00037 20.1 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO73759.1 - 0.00028 20.4 0.3 0.001 18.6 0.1 1.9 2 0 0 2 2 2 1 F-box domain Apo-CIII PF05778.7 CDO73760.1 - 0.049 13.0 0.0 12 5.4 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Velvet PF11754.3 CDO73761.1 - 6.2e-32 110.8 0.0 9.3e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Velvet factor PPR_3 PF13812.1 CDO73762.1 - 3.5e-39 129.8 9.3 0.018 15.2 0.0 14.5 15 0 0 15 15 15 8 Pentatricopeptide repeat domain PPR_2 PF13041.1 CDO73762.1 - 8.3e-34 115.3 0.3 9.4e-07 28.7 0.0 9.9 6 2 4 10 10 10 7 PPR repeat family PPR PF01535.15 CDO73762.1 - 3.8e-32 108.0 0.2 0.21 11.6 0.0 12.7 13 0 0 13 13 13 8 PPR repeat PPR_1 PF12854.2 CDO73762.1 - 6.7e-17 60.6 0.0 0.016 14.7 0.0 8.8 11 0 0 11 11 11 4 PPR repeat Mic1 PF07035.7 CDO73762.1 - 0.051 12.9 0.1 0.41 9.9 0.0 2.2 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like TPR_14 PF13428.1 CDO73762.1 - 0.1 13.2 10.3 29 5.6 0.1 7.4 8 2 1 9 9 9 0 Tetratricopeptide repeat Acetyltransf_5 PF13444.1 CDO73763.1 - 2.4e-06 28.0 0.0 0.00056 20.4 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CDO73763.1 - 0.0013 18.8 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO73763.1 - 0.0013 18.6 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HMG_box_2 PF09011.5 CDO73764.1 - 1e-13 51.4 12.7 9e-07 29.1 0.5 2.6 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 CDO73764.1 - 3.3e-13 49.6 18.3 5.2e-07 29.8 3.2 3.0 2 1 0 2 2 2 2 HMG (high mobility group) box ADSL_C PF10397.4 CDO73764.1 - 0.095 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus RP-C_C PF11800.3 CDO73766.1 - 0.12 12.0 1.2 0.18 11.4 0.1 1.7 1 1 1 2 2 2 0 Replication protein C C-terminal region Fer4 PF00037.22 CDO73767.1 - 5.5e-14 51.0 17.4 1.7e-08 33.7 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 CDO73767.1 - 5.9e-12 45.7 9.6 9.6e-12 45.1 6.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 CDO73767.1 - 2.8e-10 40.7 6.3 7e-05 23.4 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 CDO73767.1 - 4.7e-10 39.1 4.3 0.0001 22.0 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 CDO73767.1 - 8.1e-10 38.5 1.9 9e-05 22.4 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CDO73767.1 - 1.6e-09 37.4 21.8 8.2e-08 31.9 8.2 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CDO73767.1 - 4.5e-09 36.4 10.2 1.1e-08 35.2 7.2 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 CDO73767.1 - 9.6e-09 35.4 2.0 0.0015 18.8 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 CDO73767.1 - 3.2e-08 33.0 15.1 9.3e-05 22.1 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 CDO73767.1 - 7.9e-08 31.8 18.0 0.00073 19.3 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 CDO73767.1 - 2.4e-06 27.4 12.0 0.00064 19.8 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 CDO73767.1 - 1.5e-05 25.2 8.7 0.0084 16.5 0.3 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 CDO73767.1 - 0.0003 21.1 12.3 0.048 14.0 0.6 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 CDO73767.1 - 0.0033 17.9 12.5 0.18 12.3 0.8 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 CDO73767.1 - 0.019 15.0 4.0 0.092 12.8 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.2 CDO73767.1 - 0.041 14.4 18.1 0.078 13.5 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_11 PF13247.1 CDO73767.1 - 0.1 12.5 3.4 0.16 11.8 2.4 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain SET PF00856.23 CDO73769.1 - 1.2e-09 38.6 0.0 3.3e-06 27.4 0.1 2.5 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 CDO73769.1 - 2.8e-09 36.5 4.5 2.8e-09 36.5 3.1 2.6 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.1 CDO73769.1 - 0.0033 17.2 3.6 0.0033 17.2 2.5 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDO73769.1 - 0.0076 16.0 18.5 0.026 14.4 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDO73769.1 - 0.22 11.2 0.1 0.22 11.2 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CDO73769.1 - 3.9 8.2 16.4 0.74 10.5 5.3 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat DNA_mis_repair PF01119.14 CDO73770.1 - 1.9e-12 46.6 0.1 7.3e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 CDO73770.1 - 5e-06 26.1 0.2 0.00013 21.5 0.1 3.1 2 1 0 2 2 2 1 MutL C terminal dimerisation domain DNA_pol_A_exo1 PF01612.15 CDO73771.1 - 4.8e-08 32.6 0.0 1.9e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease SBDS PF01172.13 CDO73772.1 - 5.1e-15 55.0 0.0 7.1e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein ig PF00047.20 CDO73772.1 - 0.072 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin domain GATase_7 PF13537.1 CDO73772.1 - 0.084 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain DAO PF01266.19 CDO73773.1 - 3.1e-37 128.3 1.5 8e-23 80.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CDO73773.1 - 0.00016 22.0 0.0 0.0091 16.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO73773.1 - 0.00049 20.0 0.1 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CDO73773.1 - 0.0061 16.3 0.1 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CDO73773.1 - 0.035 13.9 0.0 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CDO73773.1 - 0.1 11.4 0.1 0.2 10.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Isochorismatase PF00857.15 CDO73774.1 - 4.3e-08 33.2 0.1 1.2e-07 31.8 0.0 1.8 2 1 0 2 2 2 1 Isochorismatase family AFG1_ATPase PF03969.11 CDO73775.1 - 1.9e-98 329.6 0.0 1e-94 317.3 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.1 CDO73775.1 - 0.00015 21.8 0.0 0.0018 18.3 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA PF00004.24 CDO73775.1 - 0.00076 19.6 0.0 0.0049 17.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDO73775.1 - 0.00085 19.3 0.1 0.16 11.9 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain Bac_DnaA PF00308.13 CDO73775.1 - 0.0045 16.6 0.1 0.014 15.0 0.1 1.8 1 1 0 1 1 1 1 Bacterial dnaA protein NACHT PF05729.7 CDO73775.1 - 0.068 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain GMC_oxred_N PF00732.14 CDO73776.1 - 1.1e-31 110.0 0.0 3.1e-21 75.8 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO73776.1 - 1.3e-05 25.5 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CDO73776.1 - 0.00012 21.0 0.2 0.00019 20.3 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CDO73776.1 - 0.0002 21.3 0.1 0.00056 19.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO73776.1 - 0.00045 19.2 0.3 0.0033 16.3 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CDO73776.1 - 0.0046 15.9 0.1 0.0063 15.4 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CDO73776.1 - 0.0064 16.5 0.1 0.18 11.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO73776.1 - 0.048 12.1 0.1 0.094 11.1 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 CDO73776.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 CDO73776.1 - 0.14 11.2 0.1 0.35 9.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family zf-C3HC4_2 PF13923.1 CDO73777.1 - 1.8e-08 34.2 16.6 1.8e-08 34.2 11.5 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO73777.1 - 8.8e-08 31.7 18.9 3.3e-05 23.4 7.6 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO73777.1 - 2.1e-05 24.1 21.6 0.00012 21.7 8.9 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CDO73777.1 - 0.00012 21.8 25.2 0.00014 21.6 11.1 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CDO73777.1 - 0.00016 21.2 14.6 0.00016 21.2 10.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) TMP_2 PF06791.8 CDO73777.1 - 0.00088 18.9 0.1 0.0015 18.1 0.1 1.3 1 0 0 1 1 1 1 Prophage tail length tape measure protein ALIX_LYPXL_bnd PF13949.1 CDO73777.1 - 0.0047 15.9 0.7 0.01 14.8 0.5 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV zf-Di19 PF05605.7 CDO73777.1 - 0.32 11.1 7.2 6 7.0 0.3 3.7 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding PRP21_like_P PF12230.3 CDO73777.1 - 0.35 10.3 5.2 0.57 9.6 0.1 2.8 2 1 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-RING_6 PF14835.1 CDO73777.1 - 0.62 9.8 16.1 0.18 11.6 6.3 3.2 4 0 0 4 4 4 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 CDO73777.1 - 3.7 7.1 15.7 0.31 10.5 4.9 2.7 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 CDO73777.1 - 5.3 7.0 20.0 1.7 8.5 8.7 3.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING JAB PF01398.16 CDO73778.1 - 1e-19 70.3 0.1 2.1e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CDO73778.1 - 7.4e-12 45.3 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UreF PF01730.11 CDO73779.1 - 2.6e-10 40.6 0.9 1.6e-06 28.3 0.1 2.4 2 0 0 2 2 2 2 UreF Vac14_Fig4_bd PF11916.3 CDO73780.1 - 6.1e-81 269.9 6.7 1.1e-80 269.0 4.6 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CDO73780.1 - 1.8e-41 140.4 0.1 1.1e-37 128.3 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CDO73780.1 - 3e-13 48.6 3.6 0.00013 21.7 0.0 7.4 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 CDO73780.1 - 5.1e-09 36.3 0.8 0.99 9.9 0.0 7.0 5 2 2 7 7 7 2 HEAT-like repeat ParcG PF10274.4 CDO73780.1 - 0.0018 18.1 0.7 0.95 9.3 0.0 3.4 3 0 0 3 3 3 1 Parkin co-regulated protein Cnd1 PF12717.2 CDO73780.1 - 0.0074 16.1 0.7 2.1 8.1 0.0 3.7 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF1546 PF07571.8 CDO73780.1 - 0.0087 16.1 0.0 0.12 12.5 0.0 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1546) Y_phosphatase3 PF13350.1 CDO73781.1 - 1.8e-23 83.5 0.0 3.4e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 CDO73781.1 - 2.4e-13 49.9 0.0 4.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region MCM PF00493.18 CDO73782.1 - 1.9e-137 457.5 0.5 3.1e-137 456.8 0.3 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CDO73782.1 - 5.2e-24 85.0 0.0 1.2e-23 83.9 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CDO73782.1 - 3.8e-07 29.4 0.0 3.8e-06 26.2 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CDO73782.1 - 0.0026 17.3 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CDO73782.1 - 0.0034 16.8 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 CDO73782.1 - 0.029 14.1 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FH2 PF02181.18 CDO73783.1 - 5.9e-67 226.1 0.0 5.9e-67 226.1 0.0 3.2 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_GBD PF06371.8 CDO73783.1 - 2.6e-27 95.4 0.0 9.7e-22 77.2 0.0 2.8 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 CDO73783.1 - 2.5e-23 82.4 0.9 5.9e-23 81.2 0.7 1.6 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF904 PF06005.7 CDO73783.1 - 0.64 10.3 13.2 0.37 11.1 0.2 4.4 3 1 0 3 3 3 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 CDO73783.1 - 0.68 9.7 19.2 2.5 7.9 2.3 4.9 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 CDO73783.1 - 3.1 7.8 21.7 12 5.9 3.1 4.4 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.1 CDO73783.1 - 5.5 5.3 14.0 41 2.4 9.7 2.0 1 1 0 1 1 1 0 AAA domain AATF-Che1 PF13339.1 CDO73783.1 - 5.7 7.0 13.7 0.65 10.1 3.6 3.6 3 1 1 4 4 4 0 Apoptosis antagonizing transcription factor Snapin_Pallidin PF14712.1 CDO73783.1 - 8.2 6.8 13.5 0.12 12.6 0.4 3.8 4 0 0 4 4 4 0 Snapin/Pallidin IU_nuc_hydro PF01156.14 CDO73784.1 - 4e-39 134.6 0.0 4.4e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RRN3 PF05327.6 CDO73785.1 - 1.4e-161 538.4 0.1 2.7e-161 537.4 0.0 1.4 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 F-box PF00646.28 CDO73786.1 - 0.00013 21.4 0.1 0.00033 20.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO73786.1 - 0.00098 18.8 0.1 0.00098 18.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like PQQ PF01011.16 CDO73786.1 - 0.034 13.6 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_2 PF13360.1 CDO73786.1 - 0.044 13.2 0.1 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain YHYH PF14240.1 CDO73787.1 - 0.09 12.4 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 YHYH protein Abhydrolase_6 PF12697.2 CDO73788.1 - 1.6e-34 119.7 0.0 2.3e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO73788.1 - 2.5e-17 63.1 0.0 6.7e-17 61.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO73788.1 - 2.1e-11 43.7 0.0 4e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 CDO73788.1 - 7.5e-07 27.9 0.0 2.8e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Ndr family DLH PF01738.13 CDO73788.1 - 0.0092 15.2 0.0 2.5 7.3 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CDO73788.1 - 0.015 15.1 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_4 PF08386.5 CDO73788.1 - 0.029 14.2 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Btz PF09405.5 CDO73789.1 - 1.7e-10 41.0 7.7 1.7e-10 41.0 5.4 3.6 3 1 1 4 4 4 1 CASC3/Barentsz eIF4AIII binding MFS_1 PF07690.11 CDO73790.1 - 8.1e-19 67.5 49.4 1.5e-11 43.6 15.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDO73790.1 - 4.5e-06 25.3 26.0 0.00051 18.5 7.1 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein ATG22 PF11700.3 CDO73790.1 - 0.00014 20.4 9.8 0.00021 19.8 1.1 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like DLIC PF05783.6 CDO73791.1 - 6.6e-38 130.5 0.6 1.2e-29 103.4 0.0 4.3 3 2 1 4 4 4 2 Dynein light intermediate chain (DLIC) Miro PF08477.8 CDO73791.1 - 0.00061 20.2 0.0 0.012 16.1 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 CDO73791.1 - 0.001 19.1 0.0 0.0082 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 CDO73791.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CDO73791.1 - 0.0075 15.7 0.0 0.36 10.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 CDO73791.1 - 0.022 14.2 0.1 0.057 12.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CDO73791.1 - 0.041 14.1 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 CDO73791.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CDO73791.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 CDO73791.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 CDO73791.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATP_bind_1 PF03029.12 CDO73791.1 - 0.15 11.6 0.0 4.7 6.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Egg_lysin PF01303.12 CDO73791.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) DUF3987 PF13148.1 CDO73791.1 - 0.16 10.4 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TIP41 PF04176.8 CDO73792.1 - 1.4e-53 180.8 0.0 1.8e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family zf-U11-48K PF05253.7 CDO73792.1 - 0.062 13.0 0.2 0.062 13.0 0.1 2.1 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger RRS1 PF04939.7 CDO73793.1 - 4.7e-60 201.7 6.2 8.4e-60 200.9 4.3 1.4 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) TFIIB PF00382.14 CDO73794.1 - 3.3e-35 119.7 0.0 2.6e-20 71.9 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CDO73794.1 - 3.1e-13 48.7 1.5 5.4e-13 48.0 1.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 CDO73794.1 - 0.0053 16.6 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain HTH_5 PF01022.15 CDO73794.1 - 0.0076 15.8 0.5 7.9 6.2 0.0 3.4 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family Guanylin PF02058.10 CDO73794.1 - 0.019 14.9 2.5 0.71 9.9 0.1 2.8 1 1 2 3 3 3 0 Guanylin precursor Sigma70_r4 PF04545.11 CDO73794.1 - 0.026 13.8 0.0 0.21 10.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.1 CDO73794.1 - 0.039 13.6 0.1 0.51 10.0 0.0 2.7 3 0 0 3 3 3 0 Homeodomain-like domain Cyclin_N PF00134.18 CDO73794.1 - 0.074 12.6 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain Hep_59 PF07052.6 CDO73795.1 - 5e-27 94.3 5.8 5e-27 94.3 4.0 2.3 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Spt5_N PF11942.3 CDO73795.1 - 0.00032 21.2 3.8 0.00032 21.2 2.7 3.6 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal TCTP PF00838.12 CDO73795.1 - 0.062 13.2 0.4 0.062 13.2 0.3 1.7 2 0 0 2 2 2 0 Translationally controlled tumour protein PAPS_reduct PF01507.14 CDO73796.1 - 1.2e-41 142.4 0.0 1.6e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family dsrm PF00035.20 CDO73797.1 - 2.9e-08 34.1 0.0 4.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 CDO73797.1 - 0.00012 21.9 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CDO73797.1 - 0.00095 19.5 0.0 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain Coiled-coil_56 PF09813.4 CDO73798.1 - 6.4e-07 29.2 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 COX7a PF02238.10 CDO73799.1 - 0.13 12.0 4.3 2.5 7.8 3.0 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa YEATS PF03366.11 CDO73800.1 - 8.8e-27 92.6 0.0 1.5e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 YEATS family CCDC-167 PF15188.1 CDO73800.1 - 0.46 10.4 3.4 1 9.3 2.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 APG6 PF04111.7 CDO73800.1 - 0.65 8.9 3.7 0.93 8.4 2.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 CDO73800.1 - 1.2 8.9 8.3 1.7 8.4 5.7 1.2 1 0 0 1 1 1 0 Prefoldin subunit Bap31 PF05529.7 CDO73800.1 - 2.2 7.7 5.6 3.2 7.1 3.9 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PI3_PI4_kinase PF00454.22 CDO73801.1 - 2.4e-48 164.6 0.0 4.8e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CDO73801.1 - 4.2e-34 118.0 0.0 1.3e-33 116.4 0.0 1.9 2 0 0 2 2 2 1 FAT domain UME PF08064.8 CDO73801.1 - 2.1e-23 82.2 0.4 1.8e-22 79.3 0.0 2.9 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 CDO73801.1 - 7.4e-12 44.4 0.1 1.8e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 CDO73801.1 - 9.4e-05 22.1 0.3 8.4 6.7 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 CDO73801.1 - 0.00025 20.9 0.0 0.11 12.3 0.0 4.0 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CDO73801.1 - 0.0015 18.9 0.9 1.4 9.4 0.1 5.3 4 1 1 5 5 5 1 HEAT-like repeat TSKS PF15358.1 CDO73801.1 - 0.11 10.6 5.1 0.022 12.9 0.9 1.6 2 0 0 2 2 2 0 Testis-specific serine kinase substrate Radial_spoke PF04712.7 CDO73801.1 - 0.52 8.9 0.5 0.96 8.1 0.0 1.6 2 0 0 2 2 2 0 Radial spokehead-like protein Nop14 PF04147.7 CDO73803.1 - 1.8e-260 866.4 24.5 2.2e-260 866.2 17.0 1.0 1 0 0 1 1 1 1 Nop14-like family CNH PF00780.17 CDO73804.1 - 9.7e-06 25.1 0.0 0.0013 18.1 0.0 2.6 3 0 0 3 3 3 2 CNH domain TRP PF06011.7 CDO73805.1 - 1.6e-45 155.5 32.1 3.5e-45 154.3 22.3 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CDO73805.1 - 0.00046 20.2 0.3 0.00088 19.3 0.2 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 CDO73805.1 - 0.021 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 ML domain SecE PF00584.15 CDO73805.1 - 0.28 10.8 4.1 1.1 8.9 2.8 2.1 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex ING PF12998.2 CDO73806.1 - 2.4e-13 50.2 0.3 3.2e-12 46.6 0.5 2.1 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CDO73806.1 - 3.1e-07 29.9 2.8 3.1e-07 29.9 2.0 1.6 2 0 0 2 2 2 1 PHD-finger zf-RING-like PF08746.6 CDO73806.1 - 0.039 13.9 1.3 0.095 12.7 0.9 1.6 1 0 0 1 1 1 0 RING-like domain Phage_min_cap2 PF06152.6 CDO73806.1 - 0.064 12.2 0.2 0.089 11.7 0.1 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 GATA PF00320.22 CDO73807.1 - 6.7e-09 34.9 5.5 1.2e-08 34.1 3.8 1.4 1 0 0 1 1 1 1 GATA zinc finger CUE PF02845.11 CDO73809.1 - 9.5e-06 24.9 0.1 2.5e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 CUE domain Rhomboid PF01694.17 CDO73809.1 - 9.6e-05 22.4 4.9 0.00024 21.1 3.4 1.7 1 1 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 CDO73809.1 - 0.00033 20.9 0.5 0.00055 20.2 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) eIF-3_zeta PF05091.7 CDO73810.1 - 1.2e-183 611.4 0.0 1.6e-183 611.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.17 CDO73811.1 - 6.5e-20 70.5 0.0 1.1e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO73811.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO73811.1 - 9.1e-10 38.2 0.0 1.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3_subunit PF08597.5 CDO73811.1 - 0.0023 17.5 7.8 0.0023 17.5 5.4 1.6 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit Nup35_RRM_2 PF14605.1 CDO73811.1 - 0.0092 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 CDO73811.1 - 6.9 5.0 36.6 8.9 4.6 25.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Beta_helix PF13229.1 CDO73812.1 - 6.3e-08 32.5 32.0 8.5e-06 25.6 22.2 2.9 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 CDO73812.1 - 0.00086 18.5 15.4 0.069 12.2 10.7 2.5 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Disaggr_assoc PF08480.5 CDO73812.1 - 0.0036 16.7 10.3 0.099 12.0 1.6 3.3 2 1 1 3 3 3 2 Disaggregatase related VSP PF03302.8 CDO73812.1 - 7 5.1 9.8 0.066 11.8 0.7 2.0 3 0 0 3 3 3 0 Giardia variant-specific surface protein PAP_central PF04928.12 CDO73813.1 - 1.1e-171 568.2 0.0 2.6e-108 360.6 0.0 3.2 2 1 1 3 3 3 3 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CDO73813.1 - 7.4e-86 285.4 0.1 1.4e-43 148.1 0.0 2.3 2 0 0 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CDO73813.1 - 2.9e-20 72.3 0.0 1.6e-09 37.9 0.0 2.6 2 0 0 2 2 2 2 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 CDO73813.1 - 0.00045 20.2 0.0 1.5 8.9 0.0 3.6 3 0 0 3 3 3 2 DNA polymerase beta palm Peptidase_S49 PF01343.13 CDO73813.1 - 0.00086 19.1 0.0 1.3 8.8 0.0 2.7 3 0 0 3 3 3 2 Peptidase family S49 Nrap PF03813.9 CDO73813.1 - 0.031 11.8 0.0 0.054 11.0 0.0 1.3 1 0 0 1 1 1 0 Nrap protein GlnD_UR_UTase PF08335.6 CDO73813.1 - 0.054 13.3 0.3 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase Ftsk_gamma PF09397.5 CDO73813.1 - 0.13 12.0 1.5 2.5 7.8 0.1 2.6 2 0 0 2 2 2 0 Ftsk gamma domain GatB_N PF02934.10 CDO73814.1 - 7.8e-94 313.7 0.0 1.1e-74 250.9 0.0 2.1 1 1 1 2 2 2 2 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CDO73814.1 - 1.3e-27 96.3 0.0 1.7e-16 60.2 0.0 2.2 2 0 0 2 2 2 2 GatB domain Thioredoxin_4 PF13462.1 CDO73815.1 - 3.4e-09 36.9 0.0 9e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin PYRIN PF02758.11 CDO73815.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain PCI PF01399.22 CDO73816.1 - 6.5e-14 52.1 0.0 1.4e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain VWA_2 PF13519.1 CDO73817.1 - 1.1e-06 28.8 0.8 2.7e-06 27.5 0.2 1.8 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 CDO73817.1 - 0.00017 21.4 0.1 0.0014 18.3 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain Spc7_N PF15402.1 CDO73817.1 - 0.043 11.8 0.3 0.061 11.3 0.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 VWA_3 PF13768.1 CDO73817.1 - 0.055 13.1 0.0 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Spc97_Spc98 PF04130.8 CDO73818.1 - 8e-52 176.2 0.0 1.2e-27 96.4 0.0 2.1 2 0 0 2 2 2 2 Spc97 / Spc98 family FeoC PF09012.5 CDO73818.1 - 0.21 11.3 0.0 0.53 10.0 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator Mgm101p PF06420.7 CDO73819.1 - 8e-89 295.4 0.0 1e-88 295.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Peptidase_S10 PF00450.17 CDO73823.1 - 4.2e-101 339.1 0.0 5.4e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase stn_TNFRSF12A PF12191.3 CDO73823.1 - 0.038 14.0 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SKG6 PF08693.5 CDO73823.1 - 1 8.7 4.8 2.4 7.5 3.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MoCF_biosynth PF00994.19 CDO73824.1 - 2.3e-51 173.0 0.0 3.8e-28 97.6 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 CDO73824.1 - 4.9e-28 97.5 0.0 7.7e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 CDO73824.1 - 1.2e-12 47.6 0.1 3.2e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) GDPD PF03009.12 CDO73825.1 - 1.8e-29 103.0 0.0 2.5e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 CDO73825.1 - 2.1e-05 24.5 0.6 7.8e-05 22.7 0.4 2.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MCM_N PF14551.1 CDO73825.1 - 0.084 13.3 0.0 22 5.5 0.0 2.7 2 1 1 3 3 3 0 MCM N-terminal domain GDPD PF03009.12 CDO73826.1 - 2.1e-30 106.0 0.0 4.4e-30 105.0 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 CDO73826.1 - 0.006 16.7 2.9 0.009 16.1 0.1 2.8 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Glyco_hydro_20 PF00728.17 CDO73826.1 - 0.0084 15.3 0.3 0.012 14.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Acyltransferase PF01553.16 CDO73829.1 - 5.6e-35 119.6 0.0 8.1e-35 119.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Silic_transp PF03842.8 CDO73829.1 - 0.07 11.2 0.0 0.084 10.9 0.0 1.1 1 0 0 1 1 1 0 Silicon transporter Amidohydro_1 PF01979.15 CDO73830.1 - 9.4e-19 68.2 0.1 9e-13 48.5 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 CDO73830.1 - 4.9e-13 48.6 0.0 1.3e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CDO73830.1 - 2.6e-11 43.3 0.2 3.5e-06 26.4 0.0 2.2 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 CDO73830.1 - 3.2e-10 40.5 0.9 4.6e-05 23.6 0.2 2.3 1 1 0 2 2 2 2 Amidohydrolase TPR_11 PF13414.1 CDO73832.1 - 1.1e-12 47.4 4.9 1.5e-11 43.7 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 CDO73832.1 - 7.6e-07 28.5 0.7 0.45 10.5 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDO73832.1 - 2.1e-06 27.0 0.1 0.29 10.8 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.26 CDO73832.1 - 9.3e-05 22.1 0.0 0.00037 20.2 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain DnaJ PF00226.26 CDO73832.1 - 0.0011 18.6 0.1 0.0043 16.7 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_12 PF13424.1 CDO73832.1 - 0.012 15.5 0.1 0.012 15.5 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CDO73832.1 - 0.12 12.2 0.0 18 5.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_1g PF09334.6 CDO73833.1 - 1.5e-84 283.9 0.0 8.8e-65 218.8 0.0 2.6 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CDO73833.1 - 3.5e-16 58.3 0.1 1.4e-10 39.8 0.0 3.1 1 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CDO73833.1 - 1.4e-11 44.0 0.0 6.6e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 CDO73833.1 - 0.0053 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Aldo_ket_red PF00248.16 CDO73835.1 - 1.3e-64 217.7 0.0 1.6e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SUI1 PF01253.17 CDO73836.1 - 2.6e-19 68.8 1.3 5.2e-19 67.8 0.9 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 CDO73836.1 - 0.0054 16.6 1.0 0.0092 15.8 0.7 1.4 1 0 0 1 1 1 1 Transposon-encoded protein TnpV Spore_III_AF PF09581.5 CDO73836.1 - 2.8 7.7 8.4 4.2 7.1 5.8 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DAHP_synth_2 PF01474.11 CDO73838.1 - 9.7e-181 600.9 0.0 1.1e-180 600.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family RRM_1 PF00076.17 CDO73839.1 - 0.00025 20.6 0.4 14 5.4 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMK-1 PF04802.10 CDO73840.1 - 5.2e-63 212.0 5.7 2.9e-62 209.6 3.9 2.1 1 1 0 1 1 1 1 Component of IIS longevity pathway SMK-1 RICTOR_M PF14666.1 CDO73840.1 - 0.0038 16.2 0.8 0.012 14.6 0.1 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain EVE PF01878.13 CDO73841.1 - 5e-50 169.2 0.3 7.1e-50 168.7 0.2 1.2 1 0 0 1 1 1 1 EVE domain Abhydrolase_2 PF02230.11 CDO73842.1 - 3.2e-42 144.4 0.0 4.7e-40 137.3 0.0 2.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CDO73842.1 - 3.1e-11 43.2 1.0 3.5e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO73842.1 - 1.6e-08 34.7 0.1 4.8e-08 33.1 0.1 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 CDO73842.1 - 0.0039 16.6 0.0 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Retrotrans_gag PF03732.12 CDO73843.1 - 5.3e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DPBB_1 PF03330.13 CDO73844.1 - 2e-10 40.5 0.1 2e-10 40.5 0.1 1.7 3 0 0 3 3 3 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CDO73844.1 - 0.004 16.8 0.3 0.0051 16.4 0.2 1.2 1 0 0 1 1 1 1 Barwin family DUF4473 PF14747.1 CDO73844.1 - 0.16 12.1 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) zf-A20 PF01754.11 CDO73844.1 - 0.34 10.5 0.1 0.34 10.5 0.1 1.8 2 0 0 2 2 2 0 A20-like zinc finger rve PF00665.21 CDO73846.1 - 3.7e-20 72.2 0.0 1e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CDO73846.1 - 5.8e-09 35.5 0.0 9.9e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CDO73846.1 - 0.026 14.2 0.0 0.074 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Imm47 PF15586.1 CDO73846.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 47 RVT_2 PF07727.9 CDO73847.1 - 6.6e-24 84.2 0.0 1.7e-19 69.7 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_cc PF11790.3 CDO73849.1 - 3.7e-53 180.4 0.0 4.4e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.3 CDO73850.1 - 1.8e-43 148.6 0.0 2.2e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core 7tm_6 PF02949.15 CDO73851.1 - 0.15 10.8 5.0 0.034 13.0 0.7 1.8 2 0 0 2 2 2 0 7tm Odorant receptor DUF1772 PF08592.6 CDO73851.1 - 3.4 7.3 9.6 10 5.8 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) DUF3712 PF12505.3 CDO73852.1 - 8.1e-114 374.8 57.7 2.2e-25 89.1 0.1 11.3 11 0 0 11 11 11 7 Protein of unknown function (DUF3712) LEA_2 PF03168.8 CDO73852.1 - 3e-13 50.0 17.4 0.085 13.2 0.0 8.7 9 0 0 9 9 9 5 Late embryogenesis abundant protein DUF367 PF04034.8 CDO73853.1 - 4e-50 168.7 0.0 4.9e-50 168.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CDO73853.1 - 1.1e-11 44.1 0.2 1.7e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI MRP-L27 PF09809.4 CDO73854.1 - 1.4e-10 40.7 0.2 2e-10 40.2 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SnoaL_2 PF12680.2 CDO73855.1 - 0.022 15.1 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain DDE_3 PF13358.1 CDO73857.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO73857.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Pyr_redox_3 PF13738.1 CDO73859.1 - 8.8e-31 107.5 5.1 9.7e-14 51.9 0.0 5.3 4 1 1 5 5 5 4 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CDO73859.1 - 3e-24 85.1 0.0 1.1e-06 27.1 0.0 4.5 4 1 0 4 4 4 4 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 CDO73859.1 - 2.1e-19 70.2 0.1 0.0018 18.1 0.0 4.7 4 1 0 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO73859.1 - 1.4e-11 44.6 8.4 0.014 15.7 0.0 4.6 4 0 0 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CDO73859.1 - 3.4e-11 42.6 1.2 0.0048 15.8 0.0 5.5 6 0 0 6 6 6 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 CDO73859.1 - 1.8e-10 40.3 14.7 1.9e-06 27.0 0.1 4.0 6 0 0 6 6 6 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDO73859.1 - 1.9e-10 40.6 19.3 4.6e-08 32.9 0.6 4.3 4 0 0 4 4 4 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 CDO73859.1 - 1.3e-07 31.8 1.4 0.16 12.2 0.0 4.2 4 0 0 4 4 4 2 Putative NAD(P)-binding Shikimate_DH PF01488.15 CDO73859.1 - 1e-06 28.8 2.4 0.27 11.3 0.0 4.6 5 0 0 5 5 4 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 CDO73859.1 - 1.5e-06 28.0 16.0 0.0027 17.5 0.0 6.4 6 2 1 7 7 6 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 CDO73859.1 - 4.1e-06 25.9 12.5 0.0082 15.0 0.0 4.3 4 0 0 4 4 4 2 FAD binding domain 3HCDH_N PF02737.13 CDO73859.1 - 1.6e-05 24.6 12.6 0.0028 17.3 0.0 3.0 4 0 0 4 4 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CDO73859.1 - 0.00021 20.8 9.7 3 7.3 0.4 4.3 4 0 0 4 4 4 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 CDO73859.1 - 0.00022 21.0 0.8 0.7 9.7 0.0 2.8 3 0 0 3 3 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase Amino_oxidase PF01593.19 CDO73859.1 - 0.00037 19.6 2.1 0.54 9.2 0.1 4.3 4 1 0 5 5 4 1 Flavin containing amine oxidoreductase GIDA PF01134.17 CDO73859.1 - 0.0029 16.5 14.6 0.28 10.0 0.2 4.8 5 0 0 5 5 5 2 Glucose inhibited division protein A PA PF02225.17 CDO73859.1 - 0.0043 16.7 0.2 9.4 5.9 0.0 4.0 4 0 0 4 4 4 0 PA domain 2-Hacid_dh_C PF02826.14 CDO73859.1 - 0.0049 16.0 0.2 39 3.3 0.0 4.2 4 0 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 CDO73859.1 - 0.0077 15.3 1.9 0.0077 15.3 1.3 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 CDO73859.1 - 0.011 14.2 18.1 0.17 10.3 1.5 4.2 4 0 0 4 4 4 0 HI0933-like protein MTS_N PF08468.6 CDO73859.1 - 0.013 15.3 0.5 2.2 8.1 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal UDPG_MGDP_dh_N PF03721.9 CDO73859.1 - 0.015 14.6 4.6 0.78 9.0 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ELFV_dehydrog PF00208.16 CDO73859.1 - 0.04 13.4 0.0 9.4 5.7 0.0 2.8 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.12 CDO73859.1 - 0.085 13.3 2.3 6.5 7.2 0.0 3.2 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent CPSase_L_chain PF00289.17 CDO73859.1 - 0.15 12.2 1.9 23 5.1 0.0 3.2 4 0 0 4 4 3 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Thi4 PF01946.12 CDO73859.1 - 0.24 10.4 9.7 0.38 9.8 0.1 3.7 4 0 0 4 4 4 0 Thi4 family Cons_hypoth95 PF03602.10 CDO73859.1 - 0.27 10.5 0.2 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein 95 TrkA_N PF02254.13 CDO73859.1 - 0.27 11.2 3.5 24 4.9 0.0 3.9 4 0 0 4 4 4 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 CDO73859.1 - 0.47 10.1 2.6 16 5.1 0.0 2.8 3 0 0 3 3 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 CDO73859.1 - 2.9 6.8 7.4 10 5.0 0.0 3.4 4 0 0 4 4 4 0 FAD binding domain ThiF PF00899.16 CDO73859.1 - 7.9 6.3 8.2 21 4.9 0.1 4.0 4 0 0 4 4 4 0 ThiF family ArfGap PF01412.13 CDO73860.1 - 0.054 13.2 2.4 0.18 11.5 1.6 1.8 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Ku_PK_bind PF08785.6 CDO73860.1 - 0.059 13.2 0.3 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 Ku C terminal domain like EOS1 PF12326.3 CDO73862.1 - 4.4e-17 62.0 0.2 7.9e-17 61.2 0.1 1.3 1 0 0 1 1 1 1 N-glycosylation protein Pneumo_att_G PF05539.6 CDO73862.1 - 5.8 6.1 7.4 11 5.2 5.1 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MFS_1 PF07690.11 CDO73863.1 - 1e-25 90.2 31.6 1e-25 90.2 21.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily SE PF08491.5 CDO73864.1 - 6.9e-96 320.2 0.0 9.2e-96 319.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 CDO73864.1 - 9.7e-09 34.5 0.2 0.0016 17.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CDO73864.1 - 2.5e-06 26.7 0.1 0.031 13.3 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 CDO73864.1 - 0.00013 20.7 0.3 0.17 10.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 CDO73864.1 - 0.0017 18.3 0.2 0.0039 17.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CDO73864.1 - 0.0021 17.0 0.0 0.0089 14.9 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CDO73864.1 - 0.0032 16.3 1.6 0.5 9.1 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 CDO73864.1 - 0.02 14.6 0.2 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 CDO73864.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Saccharop_dh PF03435.13 CDO73864.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 4HBT_3 PF13622.1 CDO73864.1 - 0.19 11.4 0.6 19 4.8 0.0 2.9 3 0 0 3 3 3 0 Thioesterase-like superfamily GIDA PF01134.17 CDO73864.1 - 1.5 7.5 4.2 19 3.9 2.9 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A Diphthamide_syn PF01866.12 CDO73865.1 - 7.2e-72 242.2 0.0 9.9e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPR_11 PF13414.1 CDO73866.1 - 5.4e-65 214.9 15.9 4.8e-16 58.1 0.1 7.6 2 2 7 9 9 9 8 TPR repeat TPR_1 PF00515.23 CDO73866.1 - 3.3e-45 149.9 10.5 8.5e-06 25.1 0.0 10.6 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 CDO73866.1 - 5e-42 138.4 17.1 1.4e-05 24.6 0.0 10.9 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 CDO73866.1 - 6.5e-27 93.5 18.0 3.3e-07 30.7 0.1 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 CDO73866.1 - 5.8e-24 82.2 5.0 0.00013 21.8 0.0 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 CDO73866.1 - 2.5e-22 78.6 12.9 0.00012 21.9 0.0 7.1 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 CDO73866.1 - 4.7e-20 70.2 17.7 4.9e-05 23.6 0.0 8.7 6 3 3 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 CDO73866.1 - 1.2e-17 62.3 2.9 0.0046 16.6 0.0 8.9 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 CDO73866.1 - 6.4e-17 61.6 20.2 0.00019 21.6 0.0 7.4 5 2 2 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CDO73866.1 - 1.6e-15 55.5 4.9 0.033 13.9 0.0 8.6 8 1 1 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 CDO73866.1 - 1.2e-12 47.7 7.8 0.014 15.4 0.0 4.9 4 1 2 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CDO73866.1 - 1.3e-11 44.1 12.4 0.0096 15.7 0.0 6.4 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 CDO73866.1 - 8.2e-09 35.3 13.2 0.033 14.6 0.0 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat NARP1 PF12569.3 CDO73866.1 - 0.0029 16.4 0.0 0.0029 16.4 0.0 4.0 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 CDO73866.1 - 0.0082 16.4 5.3 19 6.0 0.0 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 CDO73866.1 - 0.0092 16.0 14.3 5.4 7.2 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat DUF3856 PF12968.2 CDO73866.1 - 0.013 15.3 3.7 1.3 8.8 0.0 4.3 4 1 0 4 4 3 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 CDO73866.1 - 0.09 12.6 5.2 1.8 8.4 0.0 4.0 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Phage_term_smal PF05944.7 CDO73866.1 - 0.1 12.2 3.0 0.18 11.4 0.0 2.9 3 0 0 3 3 2 0 Phage small terminase subunit PPR PF01535.15 CDO73866.1 - 0.12 12.3 0.0 6.8 6.9 0.0 3.2 2 0 0 2 2 2 0 PPR repeat SpoIIIAH PF12685.2 CDO73866.1 - 0.78 9.1 6.5 0.087 12.3 0.9 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein TPR_11 PF13414.1 CDO73869.1 - 4.7e-12 45.3 5.8 1.4e-05 24.6 0.1 7.1 6 2 1 8 8 8 3 TPR repeat TPR_14 PF13428.1 CDO73869.1 - 1.4e-08 34.6 20.6 0.019 15.5 0.1 9.5 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 CDO73869.1 - 2.9e-08 33.2 0.0 0.066 13.4 0.0 5.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDO73869.1 - 2.4e-07 30.0 6.9 3.9e-05 23.0 0.1 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDO73869.1 - 4.9e-07 29.1 18.7 9.2e-05 22.0 0.1 7.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO73869.1 - 1.8e-06 27.3 0.0 0.062 13.1 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CDO73869.1 - 5.2e-06 26.7 12.6 0.18 12.1 0.4 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 CDO73869.1 - 5.6e-06 26.4 0.3 0.26 11.4 0.0 4.7 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CDO73869.1 - 1.3e-05 24.9 9.7 0.013 15.3 0.1 6.1 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDO73869.1 - 0.00041 20.9 22.5 0.0023 18.5 0.2 7.3 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO73869.1 - 0.009 15.7 5.6 15 5.6 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 CDO73869.1 - 0.038 13.7 0.0 6.8 6.5 0.0 3.3 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region Mito_fiss_reg PF05308.6 CDO73869.1 - 0.73 9.1 8.7 0.074 12.4 1.3 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator TPR_6 PF13174.1 CDO73869.1 - 3.2 8.4 10.2 9.7 6.9 0.3 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Nop14 PF04147.7 CDO73872.1 - 1.7 6.4 8.0 3.1 5.5 5.5 1.3 1 0 0 1 1 1 0 Nop14-like family OCD_Mu_crystall PF02423.10 CDO73873.1 - 3.2e-25 88.5 1.7 2.2e-20 72.6 0.3 2.8 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 CDO73873.1 - 0.0057 16.7 0.0 0.036 14.1 0.0 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 CDO73874.1 - 1.5e-07 31.4 0.1 5.2e-07 29.7 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Glyco_hydro_61 PF03443.9 CDO73875.1 - 5.3e-56 189.8 0.0 7.2e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAD_binding_4 PF07993.7 CDO73876.1 - 8.8e-26 90.3 0.0 1.3e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 CDO73876.1 - 1.2e-25 89.8 0.3 2.9e-12 45.6 0.0 3.1 2 1 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 CDO73876.1 - 1.3e-11 44.3 0.0 3.7e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CDO73876.1 - 4.9e-05 23.3 1.0 0.11 12.3 0.0 3.0 3 0 0 3 3 3 2 short chain dehydrogenase PP-binding PF00550.20 CDO73876.1 - 0.00047 20.3 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 CDO73876.1 - 0.011 15.7 0.0 0.44 10.5 0.0 3.1 2 1 0 2 2 2 0 NADH(P)-binding KR PF08659.5 CDO73876.1 - 0.017 14.8 0.2 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 KR domain 3Beta_HSD PF01073.14 CDO73876.1 - 0.021 13.5 0.0 0.082 11.5 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CDO73877.1 - 5.2e-26 91.0 0.0 1.3e-25 89.7 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 CDO73877.1 - 3.7e-17 61.8 0.0 4.9e-08 31.7 0.0 2.8 1 1 1 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 CDO73877.1 - 7.9e-11 41.8 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CDO73877.1 - 0.0092 16.2 0.0 0.036 14.3 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 CDO73877.1 - 0.017 15.0 0.0 0.089 12.6 0.0 2.3 1 1 0 1 1 1 0 short chain dehydrogenase SpoIID PF08486.5 CDO73878.1 - 0.068 13.4 0.1 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein Lectin_N PF03954.9 CDO73878.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain NUDIX_2 PF13869.1 CDO73879.1 - 4.1e-85 283.8 0.0 4.7e-85 283.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Abhydrolase_3 PF07859.8 CDO73880.1 - 1e-13 51.3 0.0 1.5e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 CDO73880.1 - 3.3e-07 29.3 1.7 3.8e-06 25.9 1.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CDO73880.1 - 1.1e-05 25.2 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO73880.1 - 0.012 15.5 0.4 0.016 15.0 0.3 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 CDO73880.1 - 0.026 13.1 0.0 0.43 9.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2424) Chlorophyllase2 PF12740.2 CDO73880.1 - 0.072 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme RhoGEF PF00621.15 CDO73881.1 - 1e-09 38.5 0.0 1.8e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Sulfate_transp PF00916.15 CDO73882.1 - 5.1e-43 147.0 6.3 5.1e-43 147.0 4.4 1.9 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 CDO73882.1 - 7.2e-16 57.7 0.0 1.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 CDO73882.1 - 3.6e-09 36.0 0.1 7.2e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain Cyt-b5 PF00173.23 CDO73883.1 - 3e-11 42.9 0.0 4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SBBP PF06739.6 CDO73884.1 - 0.0011 18.6 1.0 0.013 15.3 0.7 2.4 2 0 0 2 2 2 1 Beta-propeller repeat Zip PF02535.17 CDO73885.1 - 1.2e-30 106.6 3.8 1.5e-30 106.3 2.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter 7TM_GPCR_Srt PF10321.4 CDO73885.1 - 0.0092 14.7 0.3 0.15 10.7 0.0 2.0 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srt DUF4281 PF14108.1 CDO73885.1 - 0.04 13.9 0.2 0.066 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) DUF2116 PF09889.4 CDO73885.1 - 0.1 12.3 0.7 0.9 9.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3357 PF11837.3 CDO73885.1 - 0.15 11.9 0.2 5.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF2702 PF10863.3 CDO73886.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2702) DDE_3 PF13358.1 CDO73887.1 - 1.6e-12 47.4 0.6 1.7e-12 47.2 0.4 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4449 PF14613.1 CDO73889.1 - 1.8e-21 76.7 0.1 6.7e-21 74.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) RNA_pol_Rpc82 PF05645.8 CDO73890.1 - 0.033 13.7 0.3 0.058 12.9 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 SAP PF02037.22 CDO73891.1 - 0.083 12.4 0.4 7.8 6.1 0.0 3.2 3 0 0 3 3 3 0 SAP domain DEAD PF00270.24 CDO73892.1 - 3e-18 65.8 0.0 5.5e-17 61.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO73892.1 - 1.8e-11 43.7 0.1 5.3e-11 42.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CDO73892.1 - 0.026 13.3 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain T4SS-DNA_transf PF02534.9 CDO73892.1 - 0.061 11.8 0.0 0.094 11.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF563 PF04577.9 CDO73894.1 - 1.4e-19 70.8 0.4 7.1e-19 68.5 0.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF563) MA3 PF02847.12 CDO73894.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 MA3 domain OPT PF03169.10 CDO73896.1 - 4.3e-129 431.7 41.0 5.2e-129 431.4 28.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Bac_surface_Ag PF01103.18 CDO73898.1 - 2e-42 145.8 2.1 2.3e-42 145.5 1.5 1.1 1 0 0 1 1 1 1 Surface antigen OMP_b-brl PF13505.1 CDO73898.1 - 0.018 14.9 0.1 0.049 13.5 0.1 1.8 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain MatE PF01554.13 CDO73899.1 - 4.1e-37 127.3 18.0 7.8e-27 93.8 7.1 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 CDO73899.1 - 3.3e-07 30.2 6.8 3.3e-07 30.2 4.7 3.2 1 1 1 3 3 3 2 Polysaccharide biosynthesis C-terminal domain MgtE PF01769.11 CDO73899.1 - 4.5 7.5 10.7 0.05 13.8 1.2 2.4 3 0 0 3 3 3 0 Divalent cation transporter MFS_1 PF07690.11 CDO73900.1 - 1.7e-15 56.6 21.8 3.2e-15 55.7 15.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TraL PF07178.6 CDO73900.1 - 0.057 13.4 1.2 11 6.1 0.0 2.8 2 0 0 2 2 2 0 TraL protein SIN1 PF05422.7 CDO73901.1 - 7.3e-40 136.9 0.0 1.5e-26 93.0 0.0 2.2 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) RA PF00788.18 CDO73901.1 - 9.2e-05 22.8 0.0 0.00054 20.3 0.0 2.1 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain TUG-UBL1 PF11470.3 CDO73901.1 - 0.0038 17.0 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 GLUT4 regulating protein TUG FERM_N PF09379.5 CDO73901.1 - 0.007 16.3 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 FERM N-terminal domain RBD PF02196.10 CDO73901.1 - 0.051 13.3 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Raf-like Ras-binding domain F-box-like PF12937.2 CDO73902.1 - 5.8e-11 41.9 0.4 1.7e-10 40.4 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO73902.1 - 2.5e-09 36.5 0.1 6.1e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain DUF3984 PF13136.1 CDO73902.1 - 0.029 13.5 0.4 0.066 12.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Ribosomal_S8 PF00410.14 CDO73903.1 - 2.2e-15 56.6 0.0 3.1e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DcpS PF05652.7 CDO73905.1 - 3.4e-22 78.9 0.0 5.6e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 CDO73905.1 - 2.2e-16 60.1 0.0 4e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Metallophos PF00149.23 CDO73906.1 - 4.4e-11 42.5 1.1 1.2e-09 37.8 0.8 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDO73906.1 - 2.8e-07 30.4 0.0 7.2e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CDC45 PF02724.9 CDO73908.1 - 4.1 5.3 8.9 6.1 4.7 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein 3-HAO PF06052.7 CDO73909.1 - 8.5e-58 194.0 0.0 9.6e-58 193.8 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 CDO73909.1 - 5.8e-08 32.1 0.1 9e-08 31.5 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 CDO73909.1 - 0.0015 17.9 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 CDO73909.1 - 0.0029 17.3 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain A2L_zn_ribbon PF08792.5 CDO73909.1 - 0.06 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain UPF0547 PF10571.4 CDO73909.1 - 0.083 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-tcix PF14952.1 CDO73909.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Rad17 PF03215.10 CDO73910.1 - 1.2e-60 205.7 0.0 1e-59 202.6 0.0 2.0 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CDO73910.1 - 0.013 15.5 0.0 0.56 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CDO73910.1 - 0.018 15.0 0.0 0.095 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 CDO73910.1 - 0.021 15.0 0.0 0.069 13.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CDO73910.1 - 0.046 14.5 0.0 0.17 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CDO73910.1 - 0.056 13.1 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain MT0933_antitox PF14013.1 CDO73911.1 - 4.9 7.3 6.7 4 7.6 2.1 2.1 1 1 1 2 2 2 0 MT0933-like antitoxin protein Holin_LLH PF09682.5 CDO73912.1 - 0.16 12.0 0.5 0.25 11.4 0.3 1.2 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) Med15 PF09606.5 CDO73912.1 - 1.6 6.8 10.6 1.6 6.8 7.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C2H2_4 PF13894.1 CDO73913.1 - 0.00011 22.2 7.4 0.0014 18.8 0.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger FAP PF07174.6 CDO73913.1 - 0.042 13.1 2.5 0.047 12.9 1.7 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) IER PF05760.7 CDO73913.1 - 0.18 11.7 1.2 0.26 11.2 0.8 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) zf-C2H2_4 PF13894.1 CDO73914.1 - 0.0012 19.0 9.2 0.16 12.3 0.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO73914.1 - 0.69 10.3 0.1 0.69 10.3 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type ketoacyl-synt PF00109.21 CDO73915.1 - 5.5e-80 268.5 1.1 1.1e-78 264.1 0.2 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 CDO73915.1 - 7e-48 163.5 0.0 1.3e-47 162.7 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 CDO73915.1 - 9.2e-37 125.5 1.3 2.9e-36 123.9 0.9 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 CDO73915.1 - 2.4e-21 75.7 0.9 1.1e-11 44.8 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.15 CDO73915.1 - 3.2e-20 73.3 0.1 1e-19 71.6 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.2 CDO73915.1 - 7.2e-07 29.0 0.0 0.006 16.3 0.0 3.1 2 1 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 CDO73915.1 - 9.5e-05 21.5 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Dimer_Tnp_hAT PF05699.9 CDO73916.1 - 0.0014 18.2 0.6 0.0038 16.8 0.4 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.10 CDO73916.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Transposase_21 PF02992.9 CDO73917.1 - 4.1e-18 65.3 0.0 8e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO73917.1 - 0.0007 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Prominin PF05478.6 CDO73917.1 - 0.029 11.9 3.4 0.11 10.0 2.3 1.7 1 1 0 1 1 1 0 Prominin Tropomyosin PF00261.15 CDO73917.1 - 0.06 12.4 9.3 0.17 10.9 6.5 1.7 1 0 0 1 1 1 0 Tropomyosin APG6 PF04111.7 CDO73917.1 - 0.097 11.7 7.4 0.19 10.7 5.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 CDO73917.1 - 0.12 10.8 5.9 0.18 10.2 4.1 1.1 1 0 0 1 1 1 0 AAA domain SlyX PF04102.7 CDO73917.1 - 0.32 11.4 4.1 0.65 10.4 0.8 2.8 2 0 0 2 2 2 0 SlyX DUF724 PF05266.9 CDO73917.1 - 0.7 9.4 8.5 1.4 8.4 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Nsp1_C PF05064.8 CDO73917.1 - 1.3 8.6 7.8 0.18 11.4 0.2 2.7 1 1 2 3 3 3 0 Nsp1-like C-terminal region Fib_alpha PF08702.5 CDO73917.1 - 1.5 8.9 7.3 3.2 7.8 5.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Sad1_UNC PF07738.8 CDO73919.1 - 3.2e-11 43.1 0.0 3.7e-05 23.5 0.0 2.6 1 1 0 2 2 2 2 Sad1 / UNC-like C-terminal HSP20 PF00011.16 CDO73921.1 - 8.1e-23 80.2 0.5 9.9e-23 79.9 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 CDO73921.1 - 0.13 12.0 0.1 0.77 9.5 0.0 2.1 2 0 0 2 2 2 0 BON domain zf-C2H2_4 PF13894.1 CDO73922.1 - 0.014 15.7 8.0 0.32 11.4 0.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 CDO73922.1 - 0.039 14.0 3.2 0.11 12.6 0.2 2.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding CaM_binding PF07839.6 CDO73922.1 - 0.058 13.6 0.2 0.058 13.6 0.1 2.1 2 0 0 2 2 2 0 Plant calmodulin-binding domain zf-C2H2 PF00096.21 CDO73922.1 - 0.18 12.2 11.3 0.1 12.9 0.6 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Nucleo_P87 PF07267.6 CDO73922.1 - 0.89 8.1 5.4 0.12 11.0 0.9 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 zf-MIZ PF02891.15 CDO73922.1 - 2.6 7.6 6.5 5.1 6.6 3.6 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger CD45 PF12567.3 CDO73922.1 - 6.4 6.7 8.9 4.7 7.1 0.1 2.8 3 0 0 3 3 3 0 Leukocyte receptor CD45 Glyco_trans_2_3 PF13632.1 CDO73923.1 - 2.4e-53 180.7 0.9 2.4e-53 180.7 0.7 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CDO73923.1 - 1.8e-09 37.7 0.1 8.1e-09 35.6 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CDO73923.1 - 0.001 18.7 0.0 0.011 15.4 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CDO73923.1 - 0.0071 15.6 0.1 0.019 14.2 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 CDO73924.1 - 2.5e-22 79.0 0.9 5.3e-22 78.0 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 UBACT PF02134.16 CDO73925.1 - 7.6e-29 99.0 0.0 1.3e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 CDO73925.1 - 1.4e-05 25.0 0.1 0.001 19.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain HSP20 PF00011.16 CDO73926.1 - 2.9e-22 78.4 0.2 3.5e-22 78.1 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HMA PF00403.21 CDO73926.1 - 0.00074 19.6 0.0 0.023 14.8 0.0 2.1 2 0 0 2 2 2 1 Heavy-metal-associated domain BON PF04972.12 CDO73926.1 - 0.019 14.6 0.1 0.13 11.9 0.1 2.1 2 0 0 2 2 2 0 BON domain CS PF04969.11 CDO73926.1 - 0.04 14.4 0.3 1.2 9.7 0.1 2.2 2 0 0 2 2 2 0 CS domain zf-primase PF09329.6 CDO73927.1 - 6.3e-14 51.2 3.0 1.2e-13 50.4 2.0 1.5 1 0 0 1 1 1 1 Primase zinc finger SPX PF03105.14 CDO73928.1 - 1.1e-21 77.8 0.0 5.1e-20 72.3 0.0 2.4 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.1 CDO73928.1 - 6.5e-07 28.9 6.6 1e-06 28.2 4.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO73928.1 - 5.3e-06 26.1 9.6 8.8e-06 25.4 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CDO73928.1 - 6.9e-06 25.6 8.5 1.1e-05 24.9 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO73928.1 - 8.2e-06 25.7 10.5 1.3e-05 25.1 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDO73928.1 - 1.3e-05 24.9 8.2 2.3e-05 24.1 5.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CDO73928.1 - 0.00011 21.8 8.5 0.00019 21.1 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CDO73928.1 - 0.04 13.6 6.7 0.031 13.9 2.5 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 CDO73928.1 - 0.049 13.2 6.7 0.098 12.2 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CDO73928.1 - 0.075 12.8 4.0 0.14 11.9 2.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 CDO73928.1 - 0.57 9.6 6.3 1.2 8.6 4.3 1.6 1 1 0 1 1 1 0 P-11 zinc finger zf-rbx1 PF12678.2 CDO73928.1 - 1.6 8.9 7.4 3.8 7.7 5.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 CDO73928.1 - 1.7 8.2 7.0 3.4 7.2 4.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.1 CDO73928.1 - 7.7 6.1 7.7 39 3.8 5.3 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 ThiF PF00899.16 CDO73930.1 - 0.00016 21.5 0.0 0.00036 20.3 0.0 1.6 1 0 0 1 1 1 1 ThiF family DUF619 PF04768.8 CDO73931.1 - 1.9e-45 154.3 0.0 3.3e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 CDO73931.1 - 3.6e-28 98.3 0.0 8.8e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 CDO73931.1 - 2.7e-19 69.6 0.1 4.7e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 CDO73931.1 - 0.0001 22.1 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DUF2867 PF11066.3 CDO73931.1 - 0.021 14.5 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2867) Myosin_head PF00063.16 CDO73933.1 - 2.6e-242 805.7 0.0 2.6e-242 805.7 0.0 3.7 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CDO73933.1 - 9.7e-35 119.5 321.2 4.5e-22 77.6 118.7 6.2 1 1 3 4 4 4 4 Myosin tail Myosin_N PF02736.14 CDO73933.1 - 1.7e-08 34.0 1.6 4.9e-08 32.5 1.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 CDO73933.1 - 0.00046 19.7 39.9 0.00084 18.8 10.4 11.3 2 2 7 10 10 10 4 Intermediate filament protein APG6 PF04111.7 CDO73933.1 - 0.0013 17.9 20.7 0.0013 17.9 14.4 11.5 3 3 6 11 11 11 3 Autophagy protein Apg6 AAA_22 PF13401.1 CDO73933.1 - 0.013 15.6 0.0 0.013 15.6 0.0 5.3 7 0 0 7 7 7 0 AAA domain AAA_19 PF13245.1 CDO73933.1 - 0.025 14.3 0.0 0.21 11.3 0.0 2.7 1 0 0 1 1 1 0 Part of AAA domain Ribosomal_L38e PF01781.13 CDO73934.1 - 1.2e-30 104.9 0.8 1.5e-30 104.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family mTERF PF02536.9 CDO73934.1 - 0.0086 14.7 0.1 0.0098 14.5 0.0 1.0 1 0 0 1 1 1 1 mTERF DUF2774 PF11242.3 CDO73934.1 - 0.076 13.0 0.2 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Longin PF13774.1 CDO73935.1 - 8.6e-18 63.6 0.0 1.5e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CDO73935.1 - 3.4e-14 52.1 0.9 5.6e-14 51.5 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF1528 PF07515.6 CDO73935.1 - 0.088 12.8 0.0 0.88 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) Peripla_BP_6 PF13458.1 CDO73935.1 - 0.092 12.0 0.1 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein E1-E2_ATPase PF00122.15 CDO73936.1 - 1e-24 86.8 0.1 2.3e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CDO73936.1 - 5.4e-23 82.5 0.0 1.8e-22 80.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDO73936.1 - 2.9e-20 73.2 0.0 5.3e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDO73936.1 - 1.8e-05 24.5 0.0 3.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CDO73936.1 - 0.016 14.7 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CDO73936.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus zf-RING_2 PF13639.1 CDO73937.1 - 8.9e-14 51.0 7.3 1.4e-13 50.4 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDO73937.1 - 3.5e-09 36.6 3.0 5.9e-09 35.9 2.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CDO73937.1 - 6.5e-07 29.2 6.1 1e-06 28.6 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO73937.1 - 2.9e-06 26.8 3.4 4.4e-06 26.3 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CDO73937.1 - 9.7e-06 25.1 4.1 1.5e-05 24.5 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO73937.1 - 1.1e-05 25.0 3.4 1.7e-05 24.4 2.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDO73937.1 - 0.00017 21.3 3.0 0.00034 20.3 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CDO73937.1 - 0.0098 15.9 7.4 0.016 15.2 5.1 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 CDO73937.1 - 0.12 12.1 2.6 0.26 11.0 1.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 CDO73937.1 - 0.15 11.5 0.6 0.33 10.5 0.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 CDO73937.1 - 0.15 11.9 3.4 0.32 10.9 2.4 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.1 CDO73937.1 - 0.85 9.4 3.0 1.7 8.4 2.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PHD PF00628.24 CDO73937.1 - 1.1 9.0 5.4 1.8 8.3 3.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 CDO73937.1 - 8.4 6.0 6.6 15 5.2 4.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Metallophos PF00149.23 CDO73939.1 - 0.00069 19.0 0.1 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UQ_con PF00179.21 CDO73940.1 - 3.3e-36 123.8 0.0 3.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDO73940.1 - 2.3e-05 24.1 0.0 2.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CDO73940.1 - 0.013 15.1 0.1 0.027 14.1 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CDO73940.1 - 0.13 12.1 0.1 0.16 11.8 0.1 1.4 1 1 0 1 1 1 0 RWD domain SCF PF02404.10 CDO73941.1 - 0.021 14.0 0.0 0.024 13.8 0.0 1.0 1 0 0 1 1 1 0 Stem cell factor DUF1049 PF06305.6 CDO73942.1 - 0.014 14.9 0.7 0.032 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) ERG4_ERG24 PF01222.12 CDO73942.1 - 0.036 12.5 0.0 0.04 12.4 0.0 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family NpwBP PF12622.2 CDO73944.1 - 0.091 13.2 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 mRNA biogenesis factor SRP-alpha_N PF04086.8 CDO73946.1 - 0.041 13.2 5.0 0.062 12.6 3.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Methyltransf_2 PF00891.13 CDO73947.1 - 2e-19 69.7 0.1 1.3e-18 67.0 0.0 2.1 2 2 0 2 2 2 1 O-methyltransferase DUF938 PF06080.7 CDO73947.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Aldo_ket_red PF00248.16 CDO73949.1 - 2e-08 33.4 0.0 3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 CDO73951.1 - 2.5e-48 164.3 0.0 3.3e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_S10 PF00450.17 CDO73952.1 - 1.6e-18 67.0 0.0 2e-16 60.2 0.0 2.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CDO73952.1 - 0.05 13.4 0.0 0.4 10.5 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family HRDC PF00570.18 CDO73953.1 - 0.028 14.1 1.3 0.055 13.1 0.9 1.5 1 0 0 1 1 1 0 HRDC domain PSK_trans_fac PF07704.6 CDO73953.1 - 0.057 14.1 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Rv0623-like transcription factor Retrotrans_gag PF03732.12 CDO73954.1 - 1.3e-12 47.6 0.1 4.4e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO73954.1 - 0.012 15.4 0.3 0.02 14.8 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle UBN2 PF14223.1 CDO73954.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Macoilin PF09726.4 CDO73954.1 - 4.2 5.5 9.6 5.9 5.0 6.7 1.1 1 0 0 1 1 1 0 Transmembrane protein RVT_1 PF00078.22 CDO73955.1 - 1.9e-16 60.0 0.0 4.8e-16 58.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CDO73955.1 - 5.2e-10 38.9 0.1 1.5e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3770 PF12603.3 CDO73955.1 - 0.052 12.6 0.1 0.78 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3770) Prenyltrans PF00432.16 CDO73956.1 - 0.097 12.2 0.7 0.89 9.1 0.1 2.8 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat DUF2296 PF10058.4 CDO73956.1 - 2.9 7.7 7.1 0.41 10.4 1.9 1.8 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Cauli_VI PF01693.11 CDO73957.1 - 2.2e-13 49.9 0.2 8.7e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin 2OG-FeII_Oxy_3 PF13640.1 CDO73958.1 - 0.0028 18.1 0.0 0.01 16.3 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SCHIP-1 PF10148.4 CDO73958.1 - 0.0089 15.4 0.2 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 SAGA-Tad1 PF12767.2 CDO73958.1 - 1.5 8.3 7.7 2.8 7.5 5.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit vMSA PF00695.14 CDO73960.1 - 1.2 8.3 5.9 1.2 8.2 3.5 1.4 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus Bim_N PF06773.6 CDO73960.1 - 5 6.9 10.1 0.25 11.1 2.9 1.9 2 0 0 2 2 2 0 Bim protein N-terminus ERM PF00769.14 CDO73964.1 - 0.072 12.6 2.5 0.13 11.8 1.7 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3716 PF12511.3 CDO73964.1 - 1.6 8.3 13.4 0.2 11.2 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Pkinase PF00069.20 CDO73965.1 - 0.0031 16.6 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CDO73966.1 - 1e-36 126.8 0.0 1.4e-36 126.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO73966.1 - 1.2e-05 25.0 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 CDO73966.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pectinesterase PF01095.14 CDO73971.1 - 8.4e-37 126.3 0.4 6.4e-31 107.0 0.3 2.0 2 0 0 2 2 2 2 Pectinesterase DUF202 PF02656.10 CDO73972.1 - 1.4e-19 70.0 1.8 1.4e-19 70.0 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Pkinase PF00069.20 CDO73973.1 - 6.2e-68 228.7 0.0 8.5e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO73973.1 - 2.9e-42 144.5 0.0 3.9e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO73973.1 - 3.5e-10 39.3 0.0 2.2e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CDO73973.1 - 0.006 16.3 0.2 0.75 9.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CDO73973.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CDO73973.1 - 0.059 12.1 0.0 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_M16 PF00675.15 CDO73974.1 - 3.3e-54 182.6 0.2 6.1e-54 181.8 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CDO73974.1 - 3.3e-23 82.3 0.5 6.4e-12 45.5 0.0 3.9 3 1 1 4 4 4 3 Peptidase M16 inactive domain Metal_resist PF13801.1 CDO73974.1 - 0.073 13.0 0.5 0.18 11.7 0.3 1.6 1 0 0 1 1 1 0 Heavy-metal resistance DUF725 PF05267.7 CDO73974.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) CoA_transf_3 PF02515.12 CDO73975.1 - 2.5e-41 141.0 0.1 1.5e-36 125.4 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III ETF PF01012.16 CDO73976.1 - 9.4e-36 123.0 1.4 1.2e-35 122.6 1.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETC_C1_NDUFA4 PF04800.7 CDO73977.1 - 9e-12 44.7 0.0 1.1e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF3892 PF13031.1 CDO73977.1 - 0.071 13.5 0.0 0.08 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3892) UBN2_2 PF14227.1 CDO73979.1 - 2.3e-09 36.8 0.0 4.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO73979.1 - 1.2e-08 34.1 0.5 2.6e-08 33.0 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 CDO73979.1 - 1.3e-08 34.5 1.1 4.4e-08 32.8 0.8 1.9 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO73979.1 - 8.6e-08 31.9 0.0 1.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Dimer_Tnp_hAT PF05699.9 CDO73980.1 - 2e-07 30.5 0.1 5.6e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4646 PF15496.1 CDO73981.1 - 2.3e-20 72.8 0.1 7.4e-19 68.0 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) XRN_N PF03159.13 CDO73982.1 - 5.4e-106 353.3 0.0 9.4e-106 352.5 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 CDO73982.1 - 7.9e-05 22.3 1.5 0.00015 21.5 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDO73982.1 - 0.0084 15.8 0.7 0.015 15.0 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 CDO73982.1 - 0.19 11.6 1.5 0.52 10.2 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Vps52 PF04129.7 CDO73982.1 - 0.19 10.2 0.3 1.4 7.3 0.9 1.7 2 0 0 2 2 2 0 Vps52 / Sac2 family IF-2B PF01008.12 CDO73983.1 - 1.3e-85 286.8 0.1 1.6e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF4653 PF15546.1 CDO73983.1 - 0.27 10.4 2.7 0.45 9.7 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) MTP18 PF10558.4 CDO73984.1 - 4.6e-43 146.6 0.4 6.8e-43 146.1 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Fork_head PF00250.13 CDO73985.1 - 1.9e-24 85.5 0.1 1.9e-24 85.5 0.0 1.6 2 0 0 2 2 2 1 Fork head domain FHA PF00498.21 CDO73985.1 - 3.3e-07 30.3 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain IPK PF03770.11 CDO73987.1 - 9.5e-38 129.8 0.0 1.8e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Abhydrolase_6 PF12697.2 CDO73988.1 - 3e-34 118.8 0.4 5.8e-34 117.9 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO73988.1 - 5.9e-18 65.2 0.0 7.5e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO73988.1 - 1.2e-14 54.3 0.0 1.5e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ribosomal_S11 PF00411.14 CDO73988.1 - 1.8e-06 28.0 0.1 3.8e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Esterase PF00756.15 CDO73988.1 - 2.3e-05 23.9 0.0 4.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 CDO73988.1 - 0.00024 20.7 0.0 0.046 13.2 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold UPF0227 PF05728.7 CDO73988.1 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.3 CDO73988.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Ser_hydrolase PF06821.8 CDO73988.1 - 0.032 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF2305 PF10230.4 CDO73988.1 - 0.041 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Ndr PF03096.9 CDO73988.1 - 0.059 11.8 0.0 0.12 10.8 0.0 1.4 1 0 0 1 1 1 0 Ndr family BAAT_C PF08840.6 CDO73988.1 - 0.12 12.0 0.0 4 7.0 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 CDO73988.1 - 0.15 11.2 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 CDO73988.1 - 0.17 11.5 0.0 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) UDG PF03167.14 CDO73989.1 - 0.018 14.5 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily MFS_1 PF07690.11 CDO73990.1 - 9.9e-27 93.5 79.1 2.2e-20 72.6 32.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Iso_dh PF00180.15 CDO73991.1 - 7.5e-101 337.5 0.0 8.6e-101 337.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-MYND PF01753.13 CDO73994.1 - 0.0035 17.1 8.5 0.0092 15.8 5.9 1.8 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 CDO73994.1 - 0.3 10.9 3.4 0.92 9.4 2.3 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 WD40 PF00400.27 CDO73995.1 - 3.3e-30 102.8 8.2 9.2e-11 41.1 0.2 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 CDO73995.1 - 0.16 11.6 0.0 9.1 5.9 0.0 2.3 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A CRT10 PF08728.5 CDO73995.1 - 0.18 9.7 0.0 12 3.7 0.0 2.8 3 0 0 3 3 3 0 CRT10 Arf PF00025.16 CDO73996.1 - 2.1e-70 235.4 0.0 2.5e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CDO73996.1 - 1.9e-14 53.2 0.0 2.6e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CDO73996.1 - 2.2e-13 49.6 0.2 3.2e-09 35.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CDO73996.1 - 2.1e-10 40.2 0.0 2.2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CDO73996.1 - 4.8e-10 38.9 0.0 6.2e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CDO73996.1 - 1.2e-07 32.1 0.0 1.7e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CDO73996.1 - 0.00026 20.9 0.0 0.00047 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CDO73996.1 - 0.05 12.6 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CDO73996.1 - 0.13 11.6 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF2373 PF10180.4 CDO73997.1 - 2.2e-20 71.9 0.2 2.2e-20 71.9 0.1 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Aminotran_1_2 PF00155.16 CDO73998.1 - 3.2e-74 250.0 0.0 4.2e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CDO73998.1 - 5.9e-06 25.2 0.0 1.9e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CDO73998.1 - 0.00025 19.4 0.0 0.00044 18.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CDO73998.1 - 0.0053 15.9 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 CDO73999.1 - 9.7e-90 300.8 0.0 1.2e-89 300.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III cwf21 PF08312.7 CDO74000.1 - 5.2e-16 58.2 10.3 5.2e-16 58.2 7.1 2.9 3 0 0 3 3 3 1 cwf21 domain PA28_alpha PF02251.13 CDO74000.1 - 0.13 12.4 0.4 0.37 10.9 0.2 1.7 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Flavokinase PF01687.12 CDO74001.1 - 3.9e-32 110.7 0.0 5e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Bromo_TP PF07524.8 CDO74002.1 - 6.7e-09 35.3 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 CDO74002.1 - 1.8e-06 27.9 1.6 1.8e-06 27.9 1.1 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Myb_DNA-binding PF00249.26 CDO74003.1 - 2.9e-45 152.1 6.8 3.1e-12 46.3 0.0 5.7 6 0 0 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO74003.1 - 1.9e-38 130.3 8.0 2.7e-14 52.9 0.1 5.3 2 2 3 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CDO74003.1 - 2e-05 24.6 10.3 0.025 14.6 0.0 5.5 5 2 0 5 5 5 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 CDO74003.1 - 0.00064 19.5 1.0 0.89 9.4 0.1 2.5 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain RAP1 PF07218.6 CDO74003.1 - 1.2 7.1 2.2 1.7 6.6 1.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF605 PF04652.11 CDO74003.1 - 6.7 5.9 15.9 13 5.0 11.0 1.5 1 0 0 1 1 1 0 Vta1 like DUF788 PF05620.6 CDO74004.1 - 7.7e-46 156.0 0.0 8.7e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF4231 PF14015.1 CDO74004.1 - 1.4 8.9 4.0 1.2 9.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PDGLE PF13190.1 CDO74005.1 - 0.015 15.0 0.7 0.026 14.2 0.5 1.4 1 0 0 1 1 1 0 PDGLE domain RVT_2 PF07727.9 CDO74006.1 - 2.7e-77 259.0 0.0 3.9e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO74006.1 - 1e-08 35.2 0.7 1.2e-07 31.8 0.2 2.4 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 CDO74006.1 - 0.012 15.0 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain DUF605 PF04652.11 CDO74006.1 - 3.9 6.7 13.6 6.8 5.9 9.4 1.3 1 0 0 1 1 1 0 Vta1 like NmrA PF05368.8 CDO74008.1 - 1.2e-18 67.2 0.0 1.8e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CDO74008.1 - 6.5e-15 55.6 0.0 1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CDO74008.1 - 0.0025 16.5 0.0 0.017 13.8 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CLPTM1 PF05602.7 CDO74008.1 - 0.026 13.2 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) MT-A70 PF05063.9 CDO74009.1 - 1.6e-51 174.3 0.0 2.6e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Mo-nitro_C PF06967.6 CDO74009.1 - 0.0091 16.1 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 2 Mo-dependent nitrogenase C-terminus GST_N_3 PF13417.1 CDO74010.1 - 2.8e-12 46.6 0.0 4.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO74010.1 - 5.4e-11 42.5 0.0 9.4e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO74010.1 - 1.1e-09 38.1 0.0 2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CDO74010.1 - 2.4e-09 37.0 0.0 4.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO74010.1 - 2.9e-06 27.0 0.1 5.4e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GCV_T PF01571.16 CDO74011.1 - 5.4e-16 58.5 0.0 7.8e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CDO74011.1 - 0.014 15.4 0.0 0.054 13.5 0.0 2.0 2 1 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain WD40 PF00400.27 CDO74012.1 - 8.7e-37 123.6 11.3 1.4e-09 37.4 0.2 7.3 6 1 1 7 7 7 7 WD domain, G-beta repeat DEAD PF00270.24 CDO74013.1 - 7.8e-14 51.5 0.0 2.5e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO74013.1 - 5.2e-08 32.6 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.17 CDO74014.1 - 1.5e-11 43.7 0.0 4.8e-06 26.1 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO74014.1 - 1.7e-09 37.5 0.0 2e-08 34.0 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO74014.1 - 3.6e-06 26.7 0.0 0.0074 16.1 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CDO74014.1 - 0.026 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif LSM PF01423.17 CDO74015.1 - 2.6e-20 71.7 0.0 3.1e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CDO74015.1 - 0.0029 17.4 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain PfkB PF00294.19 CDO74016.1 - 5.3e-10 38.9 0.1 6.6e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Toxin_46 PF15526.1 CDO74016.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 46 DPBB_1 PF03330.13 CDO74017.1 - 3.9e-06 26.7 0.0 6.7e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CDO74017.1 - 0.0088 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Barwin family ACPS PF01648.15 CDO74018.1 - 6.2e-14 51.7 0.0 9.5e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ARD PF03079.9 CDO74019.1 - 0.0098 15.8 1.5 0.018 15.0 1.1 1.3 1 0 0 1 1 1 1 ARD/ARD' family tRNA-synt_2 PF00152.15 CDO74020.1 - 4.1e-101 338.0 0.1 7e-52 176.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 CDO74020.1 - 0.00014 21.5 0.1 0.023 14.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 CDO74020.1 - 0.042 13.0 0.0 0.94 8.6 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Asp PF00026.18 CDO74021.1 - 7.4e-67 225.8 1.6 8.9e-67 225.5 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO74021.1 - 2.2e-08 34.2 0.1 4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO74021.1 - 0.00032 21.1 0.6 0.022 15.2 0.1 2.8 2 1 0 2 2 2 1 Aspartyl protease DUF3859 PF12975.2 CDO74021.1 - 0.095 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) RapA_C PF12137.3 CDO74021.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal zf-MYND PF01753.13 CDO74022.1 - 3.4e-10 39.6 10.9 6.9e-10 38.6 7.5 1.5 1 0 0 1 1 1 1 MYND finger TPR_16 PF13432.1 CDO74022.1 - 8.3e-05 23.1 2.1 0.016 15.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDO74022.1 - 0.00077 19.8 6.6 4 8.3 0.4 4.7 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CDO74022.1 - 0.00096 18.7 1.2 1.5 8.5 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.1 CDO74022.1 - 0.043 13.6 0.2 0.14 12.0 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3366 PF11846.3 CDO74022.1 - 0.17 11.7 0.6 4.8 7.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) TPR_2 PF07719.12 CDO74022.1 - 0.4 10.7 3.8 34 4.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L19 PF01245.15 CDO74024.1 - 8.6e-11 41.6 0.6 2.6e-09 36.8 0.4 2.2 1 1 0 1 1 1 1 Ribosomal protein L19 Fungal_trans PF04082.13 CDO74025.1 - 1.5e-37 128.9 0.0 2e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.19 CDO74026.1 - 3.7e-30 105.0 0.4 8.6e-30 103.8 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DDE_1 PF03184.14 CDO74026.1 - 2.5e-28 98.7 0.0 4.3e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Acyl-CoA_dh_M PF02770.14 CDO74026.1 - 3.3e-12 45.7 0.0 6.9e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CDO74026.1 - 8.8e-11 42.1 0.6 8.8e-11 42.1 0.4 2.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CDO74026.1 - 2.3e-09 37.8 0.0 2.3e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HTH_Tnp_Tc5 PF03221.11 CDO74026.1 - 1.3e-08 34.5 0.0 4.6e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 CDO74026.1 - 3e-06 27.0 0.2 1.4e-05 24.8 0.1 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease SAP PF02037.22 CDO74026.1 - 3.8e-05 23.0 0.2 0.00099 18.5 0.0 2.5 2 0 0 2 2 2 1 SAP domain LRR_4 PF12799.2 CDO74027.1 - 0.078 12.6 0.0 1.4 8.5 0.0 2.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) MRP-S26 PF14943.1 CDO74028.1 - 0.0025 17.4 1.1 0.0029 17.1 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosome subunit S26 DUF2423 PF10338.4 CDO74029.1 - 3.4e-15 55.7 4.0 5e-15 55.1 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) DUF1707 PF08044.6 CDO74029.1 - 0.087 12.5 0.2 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Laps PF10169.4 CDO74029.1 - 0.8 9.9 3.7 1.6 8.9 2.6 1.6 1 1 0 1 1 1 0 Learning-associated protein SpoIISA_toxin PF14171.1 CDO74030.1 - 1.1 8.5 5.9 1.8 7.7 4.1 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system BOP1NT PF08145.7 CDO74031.1 - 1.1e-100 336.6 7.7 1.7e-100 336.0 5.4 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CDO74031.1 - 1.9e-23 81.3 7.2 2.7e-06 27.0 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CDO74031.1 - 0.11 11.9 0.0 23 4.5 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.7 CDO74031.1 - 0.49 9.6 15.9 0.72 9.0 11.0 1.3 1 0 0 1 1 1 0 SDA1 Actin PF00022.14 CDO74032.1 - 2.5e-112 375.1 0.0 2.9e-112 374.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CDO74032.1 - 3e-05 22.7 0.0 0.15 10.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein MOFRL PF05161.8 CDO74033.1 - 0.19 11.8 0.8 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 MOFRL family Sedlin_N PF04628.8 CDO74034.1 - 6.3e-36 123.1 0.1 6.9e-36 123.0 0.1 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CDO74034.1 - 1.8e-09 37.4 0.0 1.9e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family CDK5_activator PF03261.10 CDO74034.1 - 0.026 13.8 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Rhomboid PF01694.17 CDO74035.1 - 7.8e-20 71.3 10.9 9.4e-20 71.1 7.6 1.0 1 0 0 1 1 1 1 Rhomboid family Phage_holin_4 PF05105.7 CDO74035.1 - 0.023 14.3 0.4 0.23 11.1 0.0 2.1 1 1 1 2 2 2 0 Holin family SNARE_assoc PF09335.6 CDO74037.1 - 1.3e-12 48.0 7.5 1.3e-12 48.0 5.2 2.8 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF3816 PF12822.2 CDO74037.1 - 0.54 10.1 11.9 1.2 9.0 8.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) HrpB7 PF09486.5 CDO74038.1 - 0.00017 21.5 1.2 0.00028 20.8 0.9 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) DivIC PF04977.10 CDO74038.1 - 0.0086 15.5 0.5 0.012 15.1 0.3 1.1 1 0 0 1 1 1 1 Septum formation initiator DUF4140 PF13600.1 CDO74038.1 - 0.012 16.0 0.2 0.028 14.8 0.0 1.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spore_III_AB PF09548.5 CDO74038.1 - 0.029 14.1 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Hpt PF01627.18 CDO74038.1 - 0.11 12.4 2.6 0.28 11.1 1.9 1.5 2 0 0 2 2 2 0 Hpt domain DUF1049 PF06305.6 CDO74038.1 - 0.14 11.6 0.8 0.36 10.3 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) bZIP_2 PF07716.10 CDO74038.1 - 0.15 11.8 1.0 0.25 11.1 0.7 1.4 1 0 0 1 1 1 0 Basic region leucine zipper PEX11 PF05648.9 CDO74039.1 - 6.5e-13 48.4 1.4 2e-11 43.5 1.0 2.7 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PPR_2 PF13041.1 CDO74040.1 - 0.00011 22.1 0.1 1.2 9.2 0.0 3.8 4 0 0 4 4 4 1 PPR repeat family DUF2454 PF10521.4 CDO74040.1 - 0.025 13.6 0.5 0.19 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) PPR_3 PF13812.1 CDO74040.1 - 0.039 14.2 0.3 12 6.4 0.0 4.0 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR PF01535.15 CDO74040.1 - 0.068 13.1 0.1 33 4.7 0.0 3.3 3 0 0 3 3 3 0 PPR repeat DUF3460 PF11943.3 CDO74041.1 - 0.09 12.8 0.3 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) CLASP_N PF12348.3 CDO74043.1 - 2.1e-74 249.7 0.0 4.6e-67 225.7 0.0 4.0 3 1 1 4 4 4 2 CLASP N terminal HEAT PF02985.17 CDO74043.1 - 1.9e-07 30.5 4.8 0.19 11.9 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 CDO74043.1 - 0.0078 16.4 10.2 0.081 13.2 0.0 5.0 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 CDO74043.1 - 0.0079 16.6 8.7 0.15 12.6 0.0 5.9 6 0 0 6 6 6 1 HEAT-like repeat HSF_DNA-bind PF00447.12 CDO74044.1 - 9.5e-20 70.7 0.0 1.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase PF00069.20 CDO74045.1 - 3e-70 236.3 0.0 4.2e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74045.1 - 1.4e-30 106.2 0.2 1.7e-29 102.6 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO74045.1 - 1.2e-08 34.2 0.4 1.9e-05 23.7 0.0 2.9 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 CDO74045.1 - 0.015 14.3 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 CDO74046.1 - 9.8e-28 96.8 18.7 6e-13 48.2 9.7 4.1 3 2 1 4 4 4 3 Major Facilitator Superfamily PUCC PF03209.10 CDO74046.1 - 0.00048 18.9 2.0 0.00048 18.9 1.4 2.2 2 1 1 3 3 3 1 PUCC protein Ribosomal_S14 PF00253.16 CDO74048.1 - 1.3e-16 59.7 0.1 1.7e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF3425 PF11905.3 CDO74049.1 - 5.8e-18 65.1 2.0 1.8e-15 57.0 1.4 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) HJURP_C PF12347.3 CDO74049.1 - 8 6.1 7.4 0.35 10.4 0.8 1.9 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat DUF4187 PF13821.1 CDO74052.1 - 2.5e-22 78.2 2.0 4.4e-22 77.4 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Bgal_small_N PF02929.12 CDO74052.1 - 0.056 12.4 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Beta galactosidase small chain RRM_1 PF00076.17 CDO74053.1 - 8.4e-30 102.2 0.1 2.4e-15 55.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO74053.1 - 4.7e-22 77.7 0.0 2e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO74053.1 - 1e-08 34.8 0.0 0.00017 21.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CDO74053.1 - 0.0049 16.6 0.1 0.24 11.1 0.1 2.5 2 0 0 2 2 2 1 Limkain b1 Opi1 PF08618.5 CDO74053.1 - 0.011 14.7 0.4 0.016 14.1 0.3 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 OB_RNB PF08206.6 CDO74053.1 - 0.18 11.3 2.8 21 4.7 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain Glyco_hydro_cc PF11790.3 CDO74054.1 - 7.9e-56 189.1 0.1 1.2e-55 188.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ribosomal_L11 PF00298.14 CDO74056.1 - 2.7e-28 97.9 0.4 3.8e-28 97.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 CDO74056.1 - 4.8e-28 96.4 0.1 7.4e-28 95.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Peptidase_M28 PF04389.12 CDO74057.1 - 2e-19 69.9 0.0 3.8e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CDO74057.1 - 0.0023 17.4 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 CDO74058.1 - 0.00032 20.4 0.4 0.18 11.7 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40 PF00400.27 CDO74059.1 - 1.5e-06 27.8 0.1 0.073 12.9 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1912 PF08930.5 CDO74060.1 - 0.012 15.6 0.1 0.031 14.3 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1912) C2 PF00168.25 CDO74061.1 - 3.4e-12 46.0 0.0 6.5e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF1237 PF06824.6 CDO74062.1 - 4.5e-125 417.5 0.1 5.6e-125 417.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) DUF1640 PF07798.6 CDO74064.1 - 1.6e-14 54.3 2.2 2e-14 54.0 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Macoilin PF09726.4 CDO74064.1 - 0.0039 15.5 0.0 0.0043 15.4 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein Sds3 PF08598.6 CDO74064.1 - 0.039 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Sds3-like ADIP PF11559.3 CDO74064.1 - 0.092 12.6 4.7 0.18 11.7 3.3 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Prominin PF05478.6 CDO74064.1 - 0.12 9.9 0.9 0.16 9.4 0.6 1.1 1 0 0 1 1 1 0 Prominin DUF2800 PF10926.3 CDO74064.1 - 0.15 11.1 1.9 0.23 10.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) LUC7 PF03194.10 CDO74064.1 - 0.18 11.2 2.6 0.26 10.8 1.8 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DUF3584 PF12128.3 CDO74064.1 - 0.2 8.9 5.8 0.27 8.5 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1451 PF07295.6 CDO74064.1 - 1.1 9.0 3.4 1.6 8.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DUF4404 PF14357.1 CDO74064.1 - 4.5 7.7 7.3 6.7 7.2 2.5 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF2360 PF10152.4 CDO74064.1 - 8.9 6.5 7.5 8.7 6.6 2.7 2.4 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 CDO74064.1 - 9.6 5.4 16.7 14 4.9 11.5 1.3 1 0 0 1 1 1 0 Vta1 like Mago-bind PF09282.5 CDO74065.1 - 7.2e-13 47.8 1.0 2e-12 46.4 0.7 1.8 1 0 0 1 1 1 1 Mago binding BLVR PF06375.6 CDO74065.1 - 9.9 5.9 13.3 3.8 7.3 6.9 1.9 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) ATP_bind_1 PF03029.12 CDO74066.1 - 8.8e-62 208.7 0.0 1.4e-59 201.5 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CDO74066.1 - 5.1e-06 27.3 0.4 9.9e-06 26.3 0.3 1.7 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 CDO74066.1 - 5.6e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain T2SE PF00437.15 CDO74066.1 - 0.0012 17.8 0.0 0.0027 16.6 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 CDO74066.1 - 0.0013 18.7 0.0 0.0056 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 CDO74066.1 - 0.0018 18.1 0.0 0.0068 16.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 CDO74066.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 CDO74066.1 - 0.0028 16.7 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_29 PF13555.1 CDO74066.1 - 0.0033 16.9 0.1 0.0054 16.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CDO74066.1 - 0.0041 17.2 0.0 0.0065 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CDO74066.1 - 0.0046 16.4 0.0 0.0093 15.4 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 CDO74066.1 - 0.013 15.8 0.1 0.036 14.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CDO74066.1 - 0.016 14.9 0.0 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CDO74066.1 - 0.025 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 CDO74066.1 - 0.039 13.0 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 CDO74066.1 - 0.041 13.0 0.0 0.25 10.5 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function, DUF258 ArgK PF03308.11 CDO74066.1 - 0.041 12.6 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_24 PF13479.1 CDO74066.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CDO74066.1 - 0.056 12.9 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 CDO74066.1 - 0.062 13.2 0.0 0.21 11.4 0.0 1.9 2 1 1 3 3 3 0 AAA domain NACHT PF05729.7 CDO74066.1 - 0.065 12.8 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 CDO74066.1 - 0.068 12.9 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain Septin PF00735.13 CDO74066.1 - 0.087 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin UPF0079 PF02367.12 CDO74066.1 - 0.1 12.2 0.1 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 CDO74066.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 CDO74066.1 - 0.13 11.7 0.1 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 CDO74066.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.10 CDO74066.1 - 0.14 11.8 0.2 0.39 10.4 0.1 1.7 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.4 CDO74066.1 - 0.15 11.0 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.18 CDO74067.1 - 5.4e-09 36.1 5.4 1.4e-08 34.7 0.0 3.6 3 1 0 3 3 3 1 Dynamin family GAS PF13851.1 CDO74067.1 - 1.6 7.8 21.3 3.2 6.9 4.1 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding MFS_1 PF07690.11 CDO74069.1 - 7.3e-16 57.8 8.2 7.3e-16 57.8 5.7 2.6 2 1 1 3 3 3 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CDO74069.1 - 0.0027 17.4 0.2 0.052 13.3 0.0 2.9 2 0 0 2 2 2 1 MFS_1 like family MFS_1 PF07690.11 CDO74070.1 - 2.3e-30 105.4 23.4 3.2e-30 105.0 16.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Thiolase_N PF00108.18 CDO74071.1 - 7.2e-90 300.5 0.4 9.9e-90 300.0 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CDO74071.1 - 1.6e-38 130.9 0.8 1.6e-38 130.9 0.5 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CDO74071.1 - 8e-06 25.5 2.5 0.00086 18.8 1.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 CDO74071.1 - 0.04 13.9 0.0 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 2-Hacid_dh PF00389.25 CDO74071.1 - 0.071 12.5 0.0 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACP_syn_III PF08545.5 CDO74071.1 - 0.21 11.2 5.0 0.22 11.2 0.2 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ribosomal_S3Ae PF01015.13 CDO74072.1 - 1.2e-84 282.4 4.4 1.4e-84 282.2 3.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Ph1570 PF09638.5 CDO74072.1 - 0.077 12.7 0.2 10 5.9 0.1 2.4 2 0 0 2 2 2 0 Ph1570 protein mRNA_cap_C PF03919.10 CDO74072.1 - 0.088 13.1 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Abhydro_lipase PF04083.11 CDO74072.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Pribosyltran PF00156.22 CDO74073.1 - 1.3e-15 57.2 0.1 1.8e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_hydro_47 PF01532.15 CDO74074.1 - 4.6e-90 302.4 0.0 8.4e-67 225.7 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 PA PF02225.17 CDO74074.1 - 3.7e-07 29.7 0.1 8e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 PA domain Auto_anti-p27 PF06677.7 CDO74075.1 - 1.9e-14 53.0 3.2 1.3e-07 31.2 0.3 3.6 3 1 0 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DRP PF06044.7 CDO74075.1 - 0.013 14.5 0.1 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Dam-replacing family DUF2387 PF09526.5 CDO74075.1 - 0.051 13.4 0.7 0.67 9.9 0.2 2.4 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) RF-1 PF00472.15 CDO74079.1 - 1.7e-37 127.6 3.3 3.3e-37 126.7 2.3 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CDO74079.1 - 1.1e-31 108.9 0.0 2.5e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 PCRF domain SLT_L PF14718.1 CDO74079.1 - 0.18 11.5 2.1 0.27 11.0 0.5 2.1 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain Ribonuclease_3 PF00636.21 CDO74080.1 - 3.8e-44 149.7 0.0 3.5e-22 78.9 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CDO74080.1 - 3.6e-28 98.1 0.0 2.6e-12 46.8 0.0 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like Dicer_dimer PF03368.9 CDO74080.1 - 7.5e-06 25.6 0.0 8.5e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 Dicer dimerisation domain PAZ PF02170.17 CDO74080.1 - 0.03 13.6 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 PAZ domain COX7C PF02935.11 CDO74081.1 - 3e-13 49.3 0.6 3.3e-13 49.2 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc MFS_1 PF07690.11 CDO74082.1 - 1.6e-40 138.9 31.5 5.6e-40 137.1 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CDO74082.1 - 0.0064 14.6 0.1 0.012 13.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector Ank_2 PF12796.2 CDO74083.1 - 2e-21 76.1 0.5 7.3e-10 39.0 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CDO74083.1 - 7.9e-19 66.4 0.4 6.6e-09 35.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CDO74083.1 - 1.8e-17 63.3 1.4 5.5e-11 42.6 0.1 4.7 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDO74083.1 - 6.2e-17 61.2 0.8 6.1e-07 29.4 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO74083.1 - 6.3e-15 53.8 0.9 9.8e-06 25.3 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 CDO74083.1 - 0.0034 16.9 0.0 0.015 14.9 0.0 2.0 1 1 0 1 1 1 1 KilA-N domain DSPn PF14671.1 CDO74084.1 - 4.3e-39 133.7 0.0 1.1e-37 129.1 0.0 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CDO74084.1 - 8.2e-16 57.7 0.0 2.1e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDO74084.1 - 1.8e-05 24.2 0.0 3.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CDO74084.1 - 0.00019 21.5 0.0 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Pheromone PF08015.6 CDO74084.1 - 0.03 15.1 4.3 2.2 9.1 0.1 3.3 1 1 1 2 2 2 0 Fungal mating-type pheromone Y_phosphatase3 PF13350.1 CDO74084.1 - 0.13 12.5 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family URO-D PF01208.12 CDO74085.1 - 4.1e-121 404.1 0.0 4.7e-121 403.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) COMPASS-Shg1 PF05205.7 CDO74086.1 - 7.2e-10 39.0 0.0 9.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Ribosomal_L12 PF00542.14 CDO74088.1 - 2.7e-19 68.9 4.0 2.7e-19 68.9 2.8 2.4 2 1 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 CDO74088.1 - 0.012 15.9 6.9 0.012 15.9 4.8 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein CDC37_C PF08564.5 CDO74088.1 - 0.076 12.8 2.7 0.19 11.6 0.1 2.1 1 1 1 2 2 2 0 Cdc37 C terminal domain Coatomer_E PF04733.9 CDO74088.1 - 0.098 11.8 0.6 0.13 11.4 0.4 1.1 1 0 0 1 1 1 0 Coatomer epsilon subunit HrpB_C PF08482.5 CDO74088.1 - 0.1 12.7 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal Not3 PF04065.10 CDO74089.1 - 1.4e-96 322.3 22.9 2.2e-96 321.6 15.9 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CDO74089.1 - 1e-45 154.8 7.9 5.4e-45 152.5 5.5 2.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.8 CDO74089.1 - 0.022 14.6 1.2 0.022 14.6 0.8 3.0 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 SH3_1 PF00018.23 CDO74090.1 - 4.2e-26 90.0 0.0 3.2e-12 45.6 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CDO74090.1 - 4.9e-16 58.0 0.0 1.1e-06 28.1 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 CDO74090.1 - 1.3e-15 56.6 0.0 4.6e-10 38.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 CDO74090.1 - 3.1e-09 36.6 0.1 7.5e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 CDO74090.1 - 0.0032 17.0 0.1 0.0079 15.8 0.1 1.6 1 0 0 1 1 1 1 PB1 domain GAS2 PF02187.12 CDO74091.1 - 1.2e-08 34.5 0.0 4.7e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain CAF-1_p150 PF11600.3 CDO74091.1 - 0.00022 20.6 36.5 0.00089 18.6 25.3 2.0 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Caldesmon PF02029.10 CDO74091.1 - 0.022 13.1 36.0 0.056 11.8 24.9 1.6 1 0 0 1 1 1 0 Caldesmon Methyltransf_32 PF13679.1 CDO74091.1 - 0.73 9.5 3.1 3 7.5 1.6 2.5 1 1 0 1 1 1 0 Methyltransferase domain Tropomyosin_1 PF12718.2 CDO74092.1 - 0.0022 17.8 4.5 0.0035 17.2 3.2 1.3 1 0 0 1 1 1 1 Tropomyosin like Myosin_tail_1 PF01576.14 CDO74092.1 - 0.0055 14.4 8.6 0.0074 14.0 5.9 1.1 1 0 0 1 1 1 1 Myosin tail DUF724 PF05266.9 CDO74092.1 - 0.006 16.2 6.8 0.0092 15.6 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) IncA PF04156.9 CDO74092.1 - 0.0083 15.7 6.2 0.013 15.0 4.3 1.3 1 0 0 1 1 1 1 IncA protein ADIP PF11559.3 CDO74092.1 - 0.019 14.8 9.9 0.037 13.9 6.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PspA_IM30 PF04012.7 CDO74092.1 - 0.019 14.3 7.7 0.034 13.5 5.4 1.3 1 0 0 1 1 1 0 PspA/IM30 family EzrA PF06160.7 CDO74092.1 - 0.028 12.6 3.7 0.04 12.1 2.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4472 PF14739.1 CDO74092.1 - 0.05 14.0 3.7 0.1 13.0 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) TMF_TATA_bd PF12325.3 CDO74092.1 - 0.054 13.2 7.4 0.093 12.4 5.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cob_adeno_trans PF01923.13 CDO74092.1 - 0.066 13.0 0.6 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3391 PF11871.3 CDO74092.1 - 0.12 12.5 1.5 0.84 9.8 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) CALCOCO1 PF07888.6 CDO74092.1 - 0.27 9.4 3.9 0.39 8.9 2.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF972 PF06156.8 CDO74092.1 - 0.33 11.3 4.3 0.24 11.7 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) M PF02370.11 CDO74092.1 - 0.42 11.1 7.5 0.51 10.8 1.2 3.1 2 1 1 3 3 2 0 M protein repeat GAS PF13851.1 CDO74092.1 - 0.44 9.7 11.1 0.58 9.3 7.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 CDO74092.1 - 0.49 9.8 10.7 0.84 9.0 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Atg14 PF10186.4 CDO74092.1 - 1 8.2 8.3 1.6 7.5 5.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 CDO74092.1 - 1.5 7.7 7.9 2.1 7.3 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 CDO74092.1 - 1.7 8.2 7.5 3.3 7.3 5.2 1.4 1 0 0 1 1 1 0 Mnd1 family AAA_13 PF13166.1 CDO74092.1 - 1.7 6.9 6.8 2.3 6.5 4.7 1.1 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.8 CDO74092.1 - 2.3 9.0 7.0 4 8.2 4.9 1.3 1 0 0 1 1 1 0 Occludin homology domain Syntaxin PF00804.20 CDO74092.1 - 4.4 7.5 7.9 3 8.0 4.3 1.6 2 0 0 2 2 1 0 Syntaxin CENP-Q PF13094.1 CDO74092.1 - 6 6.8 11.1 16 5.4 7.7 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.6 CDO74092.1 - 8.5 6.1 13.0 0.8 9.4 5.6 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) R3H PF01424.17 CDO74094.1 - 4.7e-10 39.0 0.1 7.6e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 R3H domain Aconitase PF00330.15 CDO74095.1 - 6.2e-184 611.8 0.0 7.4e-184 611.5 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CDO74095.1 - 1.5e-36 125.3 0.0 2.6e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Methyltransf_16 PF10294.4 CDO74096.1 - 2.9e-47 160.3 0.0 3.6e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CDO74096.1 - 3.5e-08 34.0 0.0 6.3e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDO74096.1 - 0.00017 20.9 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CDO74096.1 - 0.00029 20.8 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CDO74096.1 - 0.0015 17.7 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 CDO74096.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain KH_1 PF00013.24 CDO74099.1 - 0.00016 21.2 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CDO74099.1 - 0.0022 17.6 0.0 0.0049 16.4 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 CDO74099.1 - 0.0061 16.1 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 KH domain GTP_cyclohydroI PF01227.17 CDO74099.1 - 0.085 12.1 0.3 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 GTP cyclohydrolase I Surface_antigen PF11054.3 CDO74099.1 - 0.14 11.5 2.1 0.15 11.3 0.8 1.5 1 1 0 1 1 1 0 Sporozoite TA4 surface antigen DUF2414 PF10309.4 CDO74100.1 - 2.7e-08 33.3 0.0 4.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FoP_duplication PF13865.1 CDO74100.1 - 2.9e-06 27.6 24.3 2e-05 24.9 4.7 3.6 3 1 1 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 BolA PF01722.13 CDO74101.1 - 1.7e-17 63.1 0.0 2.3e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein COX15-CtaA PF02628.10 CDO74102.1 - 2.4e-93 312.3 13.1 3.3e-93 311.8 9.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein TPR_14 PF13428.1 CDO74102.1 - 0.059 14.0 0.1 21 6.1 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Proteasome PF00227.21 CDO74103.1 - 7.4e-53 178.6 0.0 8.8e-53 178.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDO74103.1 - 1.8e-13 49.5 1.6 4.1e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3344 PF11824.3 CDO74103.1 - 0.065 12.6 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) Apyrase PF06079.6 CDO74103.1 - 0.071 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Apyrase Aldedh PF00171.17 CDO74105.1 - 7.4e-176 585.0 0.1 9.2e-176 584.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zn_clus PF00172.13 CDO74106.1 - 4.1e-10 39.4 9.2 5.5e-10 38.9 6.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.21 CDO74107.1 - 3.5e-60 202.5 0.1 5.1e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDO74107.1 - 3.8e-09 35.6 0.6 8.5e-09 34.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AhpC-TSA PF00578.16 CDO74108.1 - 2.4e-34 117.6 0.0 3.1e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CDO74108.1 - 5.8e-12 45.3 0.0 8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CDO74108.1 - 1.1e-08 34.5 0.1 2e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_8 PF13905.1 CDO74108.1 - 0.032 14.3 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA_2 PF13911.1 CDO74108.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ssu72 PF04722.8 CDO74109.1 - 1.2e-80 269.4 0.0 1.6e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein adh_short PF00106.20 CDO74110.1 - 1e-10 41.7 0.1 2e-10 40.8 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CDO74110.1 - 0.00013 21.6 0.1 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CDO74110.1 - 0.00025 20.8 0.0 0.0036 17.1 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 CDO74110.1 - 0.037 13.6 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Exonuc_VII_L PF02601.10 CDO74110.1 - 0.073 12.2 0.0 0.63 9.1 0.0 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF162 PF02589.10 CDO74110.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 adh_short PF00106.20 CDO74111.1 - 3.5e-28 98.5 8.0 1.3e-13 51.2 0.2 2.6 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 CDO74111.1 - 2.1e-14 53.6 2.7 6.5e-07 29.1 0.3 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 CDO74111.1 - 5.5e-12 45.9 0.1 2.8e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MoCF_biosynth PF00994.19 CDO74111.1 - 6e-05 22.4 0.1 0.17 11.2 0.0 2.9 3 0 0 3 3 3 2 Probable molybdopterin binding domain Eno-Rase_NADH_b PF12242.3 CDO74111.1 - 0.0014 18.4 0.5 1.9 8.3 0.1 2.6 2 0 0 2 2 2 2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CDO74111.1 - 0.0018 17.7 0.1 0.07 12.5 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Tau95 PF09734.4 CDO74112.1 - 1.4e-63 215.1 0.0 2.4e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Pkr1 PF08636.5 CDO74113.1 - 4.8e-15 55.3 6.4 6.3e-15 54.9 4.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Sld5 PF05916.6 CDO74114.1 - 2.4e-07 30.9 0.0 4.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein DZF PF07528.9 CDO74115.1 - 0.056 12.8 0.5 0.082 12.3 0.4 1.3 1 0 0 1 1 1 0 DZF domain Hydrolase_6 PF13344.1 CDO74115.1 - 0.062 13.2 0.1 0.34 10.8 0.1 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Radial_spoke PF04712.7 CDO74115.1 - 0.071 11.8 1.3 0.083 11.6 0.9 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein Intein_splicing PF14890.1 CDO74115.1 - 0.076 11.8 0.2 0.086 11.7 0.1 1.1 1 0 0 1 1 1 0 Intein splicing domain DUF4285 PF14113.1 CDO74115.1 - 0.17 11.8 0.5 13 5.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4285) SlyX PF04102.7 CDO74115.1 - 1.1 9.7 4.3 0.93 9.9 0.4 2.3 2 1 0 2 2 2 0 SlyX Pkinase PF00069.20 CDO74116.1 - 5.7e-73 245.2 0.4 1.7e-72 243.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74116.1 - 4.8e-37 127.4 0.2 1.2e-36 126.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO74116.1 - 0.00021 20.3 1.3 1.3 7.9 0.0 3.3 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 CDO74116.1 - 0.017 14.8 9.9 0.69 9.5 0.0 3.6 3 1 1 4 4 4 0 Phosphotransferase enzyme family Abi_2 PF07751.6 CDO74116.1 - 0.095 12.8 2.1 0.24 11.5 1.4 1.6 1 0 0 1 1 1 0 Abi-like protein TMEM51 PF15345.1 CDO74116.1 - 3.3 7.3 11.1 5 6.7 7.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Baculo_PP31 PF05311.6 CDO74116.1 - 6.2 6.0 10.6 12 5.0 7.3 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) HlyD_2 PF12700.2 CDO74116.1 - 6.9 5.7 12.5 10 5.1 8.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF1764 PF08576.5 CDO74116.1 - 8.6 7.2 10.6 18 6.2 7.4 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) EAF PF09816.4 CDO74118.1 - 2.3e-17 62.9 0.0 4.5e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Ferritin_2 PF13668.1 CDO74120.1 - 2.9e-35 121.1 0.8 5e-35 120.4 0.5 1.4 1 0 0 1 1 1 1 Ferritin-like domain FTR PF01913.13 CDO74120.1 - 0.36 10.5 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Peptidase_S10 PF00450.17 CDO74121.1 - 5.7e-77 259.6 0.0 1.1e-76 258.7 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Nop PF01798.13 CDO74122.1 - 2.4e-57 192.4 0.5 2.4e-57 192.4 0.4 2.3 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 CDO74122.1 - 1.7e-23 82.1 0.8 3e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 NOSIC (NUC001) domain NOP5NT PF08156.8 CDO74122.1 - 3.5e-20 71.9 0.2 3.5e-20 71.9 0.1 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain ATP_bind_3 PF01171.15 CDO74123.1 - 2.9e-18 66.0 0.0 4.5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 CDO74123.1 - 0.001 19.3 0.0 0.0028 17.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 CDO74123.1 - 0.016 14.6 1.4 0.016 14.6 1.0 3.4 4 0 0 4 4 4 0 RecR protein tRNA_Me_trans PF03054.11 CDO74123.1 - 0.07 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase HIPIP PF01355.12 CDO74123.1 - 0.35 11.0 6.3 5.6 7.1 0.8 3.1 3 0 0 3 3 3 0 High potential iron-sulfur protein TF_Zn_Ribbon PF08271.7 CDO74123.1 - 1.1 8.5 11.3 0.53 9.6 0.1 3.6 3 1 0 3 3 3 0 TFIIB zinc-binding DUF2616 PF11077.3 CDO74123.1 - 4.6 6.6 8.7 1.7 8.1 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) PUF PF00806.14 CDO74124.1 - 1.1e-19 68.7 0.0 0.00014 21.1 0.0 7.9 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat Bystin PF05291.6 CDO74125.1 - 5e-119 396.7 0.0 7.7e-119 396.1 0.0 1.1 1 0 0 1 1 1 1 Bystin CM_1 PF07736.6 CDO74125.1 - 0.05 13.6 0.0 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Chorismate mutase type I Epimerase PF01370.16 CDO74126.1 - 5.8e-43 147.0 0.0 1.4e-42 145.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO74126.1 - 7.4e-11 41.2 0.0 1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CDO74126.1 - 2.2e-09 36.6 0.0 7.1e-09 34.9 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CDO74126.1 - 2.1e-07 30.1 0.2 0.0027 16.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 CDO74126.1 - 0.00016 20.6 0.1 0.022 13.6 0.1 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CDO74126.1 - 0.0006 19.8 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CDO74126.1 - 0.068 13.0 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Abhydrolase_6 PF12697.2 CDO74127.1 - 3.8e-13 49.8 1.0 6.3e-13 49.1 0.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CDO74127.1 - 0.0017 18.2 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF982 PF06169.7 CDO74127.1 - 0.015 14.9 0.2 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF982) Abhydrolase_5 PF12695.2 CDO74127.1 - 0.052 13.2 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family RGS PF00615.14 CDO74129.1 - 1.4e-39 134.8 0.3 3.9e-38 130.1 0.4 2.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 CDO74129.1 - 2e-06 27.4 0.0 0.005 16.5 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_45 PF14947.1 CDO74129.1 - 0.13 12.0 0.2 2.5 7.9 0.0 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix Cyt-b5 PF00173.23 CDO74130.1 - 9e-12 44.6 0.1 2.5e-11 43.1 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Nup160 PF11715.3 CDO74132.1 - 4.7e-19 67.9 0.0 2.5e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 TPR_4 PF07721.9 CDO74132.1 - 0.011 16.0 0.2 0.066 13.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDO74132.1 - 0.058 13.2 0.8 2.1 8.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CDO74132.1 - 0.1 13.2 3.4 0.33 11.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat B12D PF06522.6 CDO74133.1 - 2.6e-14 52.6 0.4 3.2e-14 52.3 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aldo_ket_red PF00248.16 CDO74134.1 - 6.1e-41 140.1 0.0 7.5e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DALR_1 PF05746.10 CDO74134.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 DALR anticodon binding domain dCMP_cyt_deam_1 PF00383.17 CDO74135.1 - 0.00013 21.5 1.8 0.00085 18.9 1.3 2.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_13 PF13166.1 CDO74136.1 - 0.019 13.4 4.7 0.033 12.6 3.2 1.3 1 0 0 1 1 1 0 AAA domain EzrA PF06160.7 CDO74136.1 - 0.02 13.1 8.3 0.032 12.4 5.6 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Fez1 PF06818.10 CDO74136.1 - 0.062 13.3 18.8 0.14 12.1 13.0 1.6 1 0 0 1 1 1 0 Fez1 GAS PF13851.1 CDO74136.1 - 0.082 12.0 17.7 0.48 9.5 4.2 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.7 CDO74136.1 - 0.48 10.3 14.8 5.8 6.9 1.5 5.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF3450 PF11932.3 CDO74136.1 - 0.92 8.7 15.2 1.8 7.7 7.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Mnd1 PF03962.10 CDO74136.1 - 1.1 8.9 18.4 1.6e+02 1.8 12.7 2.5 1 1 0 1 1 1 0 Mnd1 family Borrelia_P83 PF05262.6 CDO74136.1 - 1.2 7.2 13.7 1.9 6.6 9.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Tmemb_cc2 PF10267.4 CDO74136.1 - 3.5 6.1 13.1 2.9 6.3 6.8 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein V_ATPase_I PF01496.14 CDO74136.1 - 4.9 4.8 5.8 7.4 4.2 4.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 CDO74136.1 - 7.6 6.0 20.9 2.3 7.7 1.9 3.8 1 1 1 3 3 3 0 Septum formation initiator ADIP PF11559.3 CDO74136.1 - 8.7 6.2 17.6 56 3.5 9.5 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DAD PF02109.11 CDO74138.1 - 3e-47 159.3 1.4 3.6e-47 159.0 1.0 1.0 1 0 0 1 1 1 1 DAD family Sod_Fe_C PF02777.13 CDO74139.1 - 2e-09 37.2 0.0 3.6e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Adap_comp_sub PF00928.16 CDO74140.1 - 2.6e-52 177.5 0.0 3.6e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family MMR_HSR1 PF01926.18 CDO74140.1 - 2.7e-16 59.5 0.0 4.8e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 CDO74140.1 - 1.4e-08 34.9 0.7 5.2e-08 33.1 0.3 2.2 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE Dynamin_N PF00350.18 CDO74140.1 - 2e-05 24.4 0.0 0.00035 20.4 0.0 2.2 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 CDO74140.1 - 0.00037 19.7 0.0 0.0007 18.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Clat_adaptor_s PF01217.15 CDO74140.1 - 0.002 17.8 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA_28 PF13521.1 CDO74140.1 - 0.0046 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDO74140.1 - 0.0072 17.1 0.0 0.026 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CDO74140.1 - 0.031 14.7 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 CDO74140.1 - 0.083 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter EF-hand_1 PF00036.27 CDO74141.1 - 6.1e-28 93.9 11.2 4.5e-08 31.8 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDO74141.1 - 1.1e-26 92.7 2.1 1e-13 51.1 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CDO74141.1 - 2.4e-21 73.6 6.9 3.1e-05 23.4 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CDO74141.1 - 3.7e-21 73.4 11.6 4.4e-06 25.7 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CDO74141.1 - 7.8e-16 57.4 11.4 5.4e-05 22.7 0.9 4.4 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CDO74141.1 - 6.1e-06 26.2 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CDO74141.1 - 2.6e-05 23.9 5.6 0.024 14.3 0.4 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CDO74141.1 - 0.0029 17.4 0.1 0.5 10.3 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain PMBR PF09373.5 CDO74141.1 - 0.08 12.9 0.0 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Pseudomurein-binding repeat Mt_ATP-synt_D PF05873.7 CDO74142.1 - 1.8e-10 40.6 0.8 2.2e-10 40.3 0.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Prominin PF05478.6 CDO74142.1 - 0.0015 16.1 0.3 0.0017 16.0 0.2 1.0 1 0 0 1 1 1 1 Prominin Cob_adeno_trans PF01923.13 CDO74142.1 - 0.0062 16.3 0.5 0.011 15.4 0.1 1.5 1 1 0 1 1 1 1 Cobalamin adenosyltransferase DUF2408 PF10303.4 CDO74142.1 - 0.0072 16.4 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) GAS PF13851.1 CDO74142.1 - 0.0091 15.2 1.5 0.012 14.8 1.1 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cas_Csy4 PF09618.5 CDO74142.1 - 0.013 15.3 0.3 0.016 15.0 0.2 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) COG6 PF06419.6 CDO74142.1 - 0.021 12.9 0.2 0.028 12.5 0.1 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF2937 PF11157.3 CDO74142.1 - 0.058 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) OmpH PF03938.9 CDO74142.1 - 0.071 13.0 4.3 0.87 9.5 3.0 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Aminotran_3 PF00202.16 CDO74142.1 - 0.084 11.7 0.8 3.9 6.2 0.0 2.4 1 1 1 2 2 2 0 Aminotransferase class-III TRADD_N PF09034.5 CDO74142.1 - 0.094 12.7 0.2 0.23 11.4 0.1 1.7 1 1 1 2 2 2 0 TRADD, N-terminal domain NPV_P10 PF05531.7 CDO74142.1 - 0.27 11.4 3.0 1.1 9.5 0.9 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Hexokinase_2 PF03727.11 CDO74143.1 - 1e-65 221.3 0.0 2.5e-37 128.3 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 CDO74143.1 - 6.4e-62 208.5 0.0 1.3e-61 207.5 0.0 1.5 1 1 0 1 1 1 1 Hexokinase Fungal_trans PF04082.13 CDO74144.1 - 4.8e-14 51.8 0.1 9.9e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NACHT PF05729.7 CDO74145.1 - 3.9e-05 23.3 0.0 0.00016 21.4 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 CDO74145.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_11 PF13414.1 CDO74146.1 - 2.6e-63 209.6 26.8 5.9e-21 73.8 1.5 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 CDO74146.1 - 4.3e-56 184.3 27.3 6.2e-10 38.2 0.6 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 CDO74146.1 - 6.5e-47 153.7 27.6 2.4e-08 33.2 0.3 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 CDO74146.1 - 1.3e-29 102.2 13.4 7.2e-09 36.0 0.3 6.6 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 CDO74146.1 - 1.4e-29 101.8 18.1 1.5e-12 47.2 0.0 6.7 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 CDO74146.1 - 2.1e-28 95.9 18.8 0.00021 20.8 0.1 9.5 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 CDO74146.1 - 8.2e-25 84.9 10.3 0.0015 18.5 0.1 8.4 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 CDO74146.1 - 2.1e-23 80.1 7.1 0.0034 17.0 0.0 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 CDO74146.1 - 2.3e-23 82.3 12.4 8.8e-08 32.3 0.0 7.0 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CDO74146.1 - 1.3e-21 75.0 18.8 0.002 18.5 0.0 9.9 6 3 5 11 11 9 7 Tetratricopeptide repeat TPR_9 PF13371.1 CDO74146.1 - 3.6e-14 52.3 11.9 0.00011 22.0 0.1 6.1 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 CDO74146.1 - 1.3e-12 47.2 22.8 0.18 12.3 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 CDO74146.1 - 2.3e-11 43.6 10.9 0.001 19.1 0.1 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 CDO74146.1 - 1.1e-06 28.3 13.3 0.67 9.8 0.2 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 CDO74146.1 - 0.00055 19.7 11.1 7.8 6.5 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat SPO22 PF08631.5 CDO74146.1 - 0.0018 17.4 0.5 0.096 11.7 0.0 3.5 5 1 0 5 5 3 1 Meiosis protein SPO22/ZIP4 like NARP1 PF12569.3 CDO74146.1 - 0.0056 15.5 2.3 0.0056 15.5 1.6 4.0 2 2 2 4 4 3 1 NMDA receptor-regulated protein 1 MAS20 PF02064.10 CDO74146.1 - 0.0085 15.9 1.3 5 7.0 0.0 4.1 3 1 1 4 4 4 0 MAS20 protein import receptor Sec5 PF15469.1 CDO74146.1 - 0.0099 15.6 2.1 1.9 8.2 0.1 3.7 3 0 0 3 3 3 1 Exocyst complex component Sec5 RPN7 PF10602.4 CDO74146.1 - 0.022 14.1 8.2 5.3 6.3 0.2 5.1 3 1 1 4 4 4 0 26S proteasome subunit RPN7 XPC-binding PF09280.6 CDO74146.1 - 0.029 13.8 8.1 1 8.8 0.5 2.7 2 0 0 2 2 2 0 XPC-binding domain TPR_20 PF14561.1 CDO74146.1 - 0.033 14.3 18.9 0.3 11.2 0.1 5.2 5 1 0 6 6 4 0 Tetratricopeptide repeat SapC PF07277.6 CDO74146.1 - 0.037 13.3 0.1 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 SapC MIT PF04212.13 CDO74146.1 - 0.042 13.7 22.8 1.6 8.6 0.2 7.1 4 2 2 6 6 6 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.1 CDO74146.1 - 0.11 12.7 10.3 9.3 6.4 0.3 4.4 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.1 CDO74146.1 - 0.12 12.3 7.0 5.9 6.8 0.0 5.3 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat DUF3702 PF12486.3 CDO74146.1 - 0.15 11.7 2.5 0.65 9.6 0.1 2.4 2 0 0 2 2 2 0 ImpA domain protein BTAD PF03704.12 CDO74146.1 - 0.88 9.8 14.0 43 4.3 0.4 5.3 3 2 1 5 5 5 0 Bacterial transcriptional activator domain DUF357 PF04010.8 CDO74146.1 - 1.2 8.8 5.0 1.2 8.8 0.0 3.5 4 1 0 4 4 3 0 Protein of unknown function (DUF357) Sel1 PF08238.7 CDO74146.1 - 7.1 7.4 8.0 18 6.1 0.0 4.7 5 0 0 5 5 3 0 Sel1 repeat EphA2_TM PF14575.1 CDO74147.1 - 0.00047 20.4 0.0 0.00061 20.1 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Colicin_V PF02674.11 CDO74147.1 - 0.0085 15.9 0.3 0.011 15.6 0.2 1.1 1 0 0 1 1 1 1 Colicin V production protein Syndecan PF01034.15 CDO74147.1 - 0.011 15.3 0.3 0.016 14.8 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain DUF3147 PF11345.3 CDO74147.1 - 0.012 15.6 0.4 0.016 15.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) WBP-1 PF11669.3 CDO74147.1 - 0.023 14.7 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 Beta-APP PF03494.8 CDO74147.1 - 1.1 8.7 3.9 2 7.9 2.7 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Golgin_A5 PF09787.4 CDO74149.1 - 0.19 10.2 1.2 0.31 9.5 0.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 p450 PF00067.17 CDO74150.1 - 8.3e-56 189.4 0.0 1.8e-55 188.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 bZIP_1 PF00170.16 CDO74152.1 - 4.7e-11 42.4 8.6 4.7e-11 42.4 6.0 1.6 2 0 0 2 2 2 1 bZIP transcription factor Aft1_HRA PF11786.3 CDO74152.1 - 5.6e-08 32.9 14.2 5.6e-08 32.9 9.9 3.9 3 1 0 3 3 3 1 Aft1 HRA domain bZIP_2 PF07716.10 CDO74152.1 - 3.1e-06 26.8 8.7 3.1e-06 26.8 6.0 1.8 2 0 0 2 2 2 1 Basic region leucine zipper DUF3469 PF11952.3 CDO74152.1 - 0.037 13.6 0.4 0.088 12.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) Herpes_LMP2 PF07415.6 CDO74153.1 - 6.2 5.2 4.7 10 4.5 3.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Shisa PF13908.1 CDO74154.1 - 0.63 10.2 0.0 0.63 10.2 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Aldo_ket_red PF00248.16 CDO74155.1 - 4e-43 147.2 0.0 4.5e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L18e PF00828.14 CDO74156.1 - 3.9e-24 85.4 0.0 3.9e-24 85.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 CDO74157.1 - 1.9e-17 62.6 0.5 2.5e-17 62.2 0.0 1.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO74157.1 - 1.4e-16 60.2 0.2 4e-16 58.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO74157.1 - 1.9e-15 56.4 0.2 2.8e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.16 CDO74158.1 - 3.8e-37 127.6 0.0 4.6e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.3 CDO74158.1 - 0.019 14.8 0.0 0.75 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) DUF2454 PF10521.4 CDO74159.1 - 2.5e-24 85.7 0.0 5.2e-24 84.7 0.0 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF2454) Pkinase PF00069.20 CDO74162.1 - 1.2e-17 63.9 0.0 2.2e-15 56.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74162.1 - 4.5e-07 29.1 0.0 2.4e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2454 PF10521.4 CDO74163.1 - 2.2e-15 56.4 0.0 3.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Pkinase PF00069.20 CDO74165.1 - 8.3e-06 25.1 0.0 0.0011 18.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase PF00069.20 CDO74166.1 - 8.1e-10 38.2 0.0 1.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CDO74166.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 CDO74166.1 - 0.031 13.3 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Cyclin PF08613.6 CDO74167.1 - 8.9e-41 139.7 0.4 2.2e-40 138.5 0.3 1.7 1 1 0 1 1 1 1 Cyclin PRKCSH-like PF12999.2 CDO74169.1 - 3.6e-50 169.9 0.3 7.8e-50 168.8 0.2 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CDO74169.1 - 2.7e-29 101.6 0.1 6.3e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CDO74169.1 - 3.5e-08 34.1 0.3 1.1e-07 32.5 0.2 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 CDO74169.1 - 0.054 13.4 12.5 1.2 9.0 1.4 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A TMF_DNA_bd PF12329.3 CDO74169.1 - 4.2 7.2 20.4 1.9 8.3 3.8 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CDO74169.1 - 5.8 6.4 21.4 6.4 6.3 0.1 3.2 1 1 2 3 3 3 0 IncA protein Ribosomal_L2_C PF03947.13 CDO74170.1 - 1.5e-42 144.4 1.8 2.1e-42 143.9 1.2 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CDO74170.1 - 2.9e-15 55.9 0.0 6.7e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain FGGY_C PF02782.11 CDO74171.1 - 4.3e-48 163.5 0.3 6.1e-48 163.0 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CDO74171.1 - 1.9e-22 79.8 0.0 6.2e-22 78.1 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 CDO74171.1 - 0.00023 20.5 2.7 0.23 10.6 0.2 2.8 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.16 CDO74171.1 - 0.0017 17.7 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Hexokinase UPF0075 PF03702.9 CDO74171.1 - 0.0026 16.7 0.2 0.0072 15.2 0.1 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0075) Geminin PF07412.7 CDO74171.1 - 0.0085 15.7 0.5 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Geminin CmcH_NodU PF02543.10 CDO74171.1 - 0.045 12.8 0.2 0.093 11.8 0.1 1.5 1 1 0 1 1 1 0 Carbamoyltransferase Cyclin PF08613.6 CDO74172.1 - 5.6e-08 33.3 0.0 5.9e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CDO74172.1 - 3.1e-05 23.5 0.1 4.3e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_S25 PF03297.10 CDO74173.1 - 1.7e-41 140.5 3.5 1.8e-41 140.3 2.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 CDO74173.1 - 0.015 14.6 0.4 0.024 14.0 0.3 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SH3_9 PF14604.1 CDO74175.1 - 1.2e-07 31.1 0.1 2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CDO74175.1 - 6.9e-05 22.2 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CDO74175.1 - 0.00038 19.7 0.1 0.00057 19.2 0.1 1.3 1 0 0 1 1 1 1 SH3 domain Cyclin PF08613.6 CDO74176.1 - 1.1e-14 55.1 0.0 2.1e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CDO74176.1 - 1.1e-14 54.0 0.1 1.8e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain UAA PF08449.6 CDO74177.1 - 7.1e-13 48.1 0.0 1.3e-11 43.9 0.0 2.1 1 1 1 2 2 2 1 UAA transporter family FAD_binding_4 PF01565.18 CDO74177.1 - 0.06 12.8 0.3 0.1 12.0 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain MIF4G_like PF09088.6 CDO74178.1 - 5.7e-60 202.0 0.0 9.9e-60 201.2 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 CDO74178.1 - 6.2e-41 140.3 0.0 9.5e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 CDO74178.1 - 1.8e-05 24.2 0.0 5.8e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 MIF4G domain PPR_3 PF13812.1 CDO74179.1 - 4.2e-08 32.8 1.1 0.15 12.3 0.0 6.4 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 CDO74179.1 - 2.9e-05 23.9 0.0 2.8 7.9 0.0 5.3 7 0 0 7 7 7 2 PPR repeat family PPR_1 PF12854.2 CDO74179.1 - 0.00028 20.2 0.0 1.6 8.3 0.0 3.7 3 0 0 3 3 3 2 PPR repeat PPR PF01535.15 CDO74179.1 - 0.00042 20.1 0.4 0.43 10.6 0.0 5.0 6 0 0 6 6 6 1 PPR repeat FAD_binding_3 PF01494.14 CDO74180.1 - 3.8e-20 72.2 0.1 8.2e-10 38.2 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CDO74180.1 - 0.001 19.0 0.7 0.0024 17.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 CDO74180.1 - 0.026 13.3 0.0 0.063 12.0 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_3 PF01494.14 CDO74181.1 - 2.2e-24 86.1 0.1 9.8e-24 84.0 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CDO74181.1 - 4.8e-05 23.2 0.1 0.00011 22.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 CDO74181.1 - 0.00073 18.2 0.2 0.0062 15.2 0.0 2.0 1 1 1 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 CDO74181.1 - 0.00076 18.5 0.0 0.0035 16.3 0.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CDO74181.1 - 0.0032 17.5 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO74181.1 - 0.015 15.0 0.7 0.18 11.5 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CDO74181.1 - 0.054 13.3 0.2 0.57 10.0 0.2 2.3 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO74181.1 - 0.076 11.4 0.0 0.28 9.6 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 CDO74181.1 - 0.092 13.1 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9_N PF02897.10 CDO74182.1 - 2.1e-93 313.1 4.1 3.1e-93 312.5 2.9 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CDO74182.1 - 9.6e-32 109.9 0.1 7.8e-18 64.4 0.0 3.5 3 0 0 3 3 3 3 Prolyl oligopeptidase family CheW PF01584.14 CDO74182.1 - 0.21 11.0 0.0 0.42 10.0 0.0 1.4 1 0 0 1 1 1 0 CheW-like domain Mito_carr PF00153.22 CDO74183.1 - 6.6e-64 211.6 1.7 7.4e-22 76.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.17 CDO74184.1 - 1.1e-22 79.6 0.6 1.7e-22 78.9 0.4 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CDO74184.1 - 0.0016 18.2 1.4 0.025 14.4 1.0 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 CDO74184.1 - 0.0026 17.4 0.1 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Acyl-CoA_dh_1 PF00441.19 CDO74186.1 - 2.4e-29 102.3 0.3 3.9e-29 101.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CDO74186.1 - 8.3e-20 70.0 0.4 2.1e-19 68.7 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 CDO74186.1 - 7e-19 67.4 0.0 1.9e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 CDO74186.1 - 2.8e-11 44.0 0.0 8.8e-11 42.3 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CDO74186.1 - 1.3e-05 25.4 0.1 2.3e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SNF2_N PF00176.18 CDO74187.1 - 2e-67 227.0 0.0 3e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Epimerase PF01370.16 CDO74187.1 - 6.7e-34 117.3 0.0 1.6e-33 116.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glycos_transf_2 PF00535.21 CDO74187.1 - 7.8e-16 58.2 0.6 4.5e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CDO74187.1 - 1.7e-14 54.1 1.0 6.4e-12 45.7 0.0 2.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Helicase_C PF00271.26 CDO74187.1 - 4.8e-11 42.3 0.0 2.7e-10 39.9 0.0 2.3 3 0 0 3 3 2 1 Helicase conserved C-terminal domain 3Beta_HSD PF01073.14 CDO74187.1 - 7.4e-10 37.9 0.0 1.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_tranf_2_2 PF10111.4 CDO74187.1 - 3.3e-08 32.9 0.0 5.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ResIII PF04851.10 CDO74187.1 - 5.6e-06 26.3 0.4 1.1e-05 25.2 0.0 1.7 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 CDO74187.1 - 1e-05 25.2 5.0 3.4e-05 23.5 3.5 1.9 1 0 0 1 1 1 1 Ring finger domain NAD_binding_10 PF13460.1 CDO74187.1 - 1.1e-05 25.5 0.2 0.00039 20.4 0.0 2.5 2 0 0 2 2 2 1 NADH(P)-binding zf-C3HC4 PF00097.20 CDO74187.1 - 3e-05 23.5 5.6 6.6e-05 22.4 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO74187.1 - 0.00012 22.0 4.6 0.00036 20.4 3.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDO74187.1 - 0.00039 20.2 4.9 0.00089 19.0 3.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CDO74187.1 - 0.00064 19.3 3.8 0.0017 18.0 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NmrA PF05368.8 CDO74187.1 - 0.0014 17.8 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family zf-Nse PF11789.3 CDO74187.1 - 0.0031 17.0 2.2 0.0064 15.9 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 CDO74187.1 - 0.014 15.4 1.5 0.031 14.3 1.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 CDO74187.1 - 0.18 11.6 3.6 0.06 13.1 0.3 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CDO74187.1 - 0.22 11.2 5.3 0.5 10.1 3.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DEAD_2 PF06733.10 CDO74187.1 - 0.46 9.8 3.0 0.37 10.1 0.1 2.3 2 1 0 2 2 2 0 DEAD_2 zf-RING_UBOX PF13445.1 CDO74187.1 - 0.83 9.4 3.0 2.4 7.9 2.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Glyco_transf_8 PF01501.15 CDO74188.1 - 1.5e-28 99.7 0.0 1.3e-27 96.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.1 CDO74188.1 - 2.9e-16 60.2 0.0 9e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 CDO74188.1 - 8.8e-05 21.6 0.0 0.00024 20.2 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase DUF2076 PF09849.4 CDO74189.1 - 4.8e-05 23.5 2.4 4.8e-05 23.5 1.7 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) WW PF00397.21 CDO74189.1 - 0.0024 17.7 1.4 0.0024 17.7 1.0 2.2 2 0 0 2 2 2 1 WW domain HMG_box PF00505.14 CDO74190.1 - 3.1e-16 59.3 2.4 3.1e-16 59.3 1.6 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDO74190.1 - 1.5e-10 41.3 2.3 1.5e-10 41.3 1.6 1.8 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.8 CDO74190.1 - 0.0002 21.6 0.9 0.0002 21.6 0.6 1.8 2 0 0 2 2 2 1 YABBY protein DUF1074 PF06382.6 CDO74190.1 - 0.04 13.8 1.0 0.066 13.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1074) Med26 PF08711.6 CDO74191.1 - 2.3e-05 23.8 0.0 8.1e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 TFIIS helical bundle-like domain Acid_PPase PF12689.2 CDO74191.1 - 0.14 11.7 0.9 0.28 10.8 0.7 1.4 1 0 0 1 1 1 0 Acid Phosphatase TP53IP5 PF15331.1 CDO74191.1 - 0.54 10.1 7.5 5.4 6.8 5.6 2.2 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 LIM_bind PF01803.11 CDO74192.1 - 8.4e-49 165.8 2.0 2.5e-48 164.2 0.0 2.4 2 1 0 2 2 2 1 LIM-domain binding protein Kinesin PF00225.18 CDO74193.1 - 4.5e-109 364.1 0.0 8.2e-109 363.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 CDO74193.1 - 1.6e-41 141.2 0.0 3.5e-41 140.1 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 CDO74193.1 - 9.6e-12 45.0 0.0 3.9e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 PH domain KIF1B PF12423.3 CDO74193.1 - 1.1e-05 25.3 0.8 2.6e-05 24.1 0.6 1.7 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 CDO74193.1 - 0.00013 22.0 0.0 0.00078 19.5 0.0 2.3 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.1 CDO74193.1 - 0.044 14.0 0.1 0.26 11.5 0.1 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain Ribosomal_S4 PF00163.14 CDO74194.1 - 2.6e-15 56.5 0.7 3.7e-15 56.0 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CDO74194.1 - 9.7e-11 40.9 0.0 1.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain HemX PF04375.9 CDO74195.1 - 0.052 12.1 0.1 0.07 11.7 0.1 1.1 1 0 0 1 1 1 0 HemX Cyt-b5 PF00173.23 CDO74196.1 - 3.3e-15 55.6 0.1 7e-15 54.5 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arf PF00025.16 CDO74197.1 - 2.7e-61 205.8 1.2 3e-60 202.4 0.8 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CDO74197.1 - 7.3e-08 31.5 0.4 0.00011 21.1 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CDO74197.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CDO74197.1 - 8.1e-06 25.1 0.0 2.2e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CDO74197.1 - 0.0039 16.6 0.0 0.038 13.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CDO74197.1 - 0.015 15.8 0.0 0.028 14.9 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 CDO74197.1 - 0.09 12.4 0.1 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain GTP_EFTU PF00009.22 CDO74198.1 - 5e-33 114.1 0.0 2.9e-32 111.6 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CDO74198.1 - 2.2e-17 62.8 0.0 6.3e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CDO74198.1 - 5.3e-14 52.0 3.8 1.9e-10 40.7 0.1 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CDO74198.1 - 1.1e-06 28.5 0.0 3.8e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CDO74198.1 - 0.0027 17.2 0.0 0.0063 16.0 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 CDO74198.1 - 0.01 15.9 0.1 0.033 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 CDO74198.1 - 0.038 13.3 0.0 0.18 11.1 0.0 2.3 1 1 0 1 1 1 0 Ras family AA_permease_2 PF13520.1 CDO74199.1 - 4.4e-42 144.1 53.4 5.6e-42 143.7 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CDO74199.1 - 1.2e-23 83.2 41.4 1.6e-23 82.8 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease AMP_N PF05195.11 CDO74200.1 - 3.8e-24 84.6 0.0 5.9e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.19 CDO74201.1 - 3.5e-26 92.0 0.0 4.7e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2433 PF10360.4 CDO74203.1 - 7e-30 104.0 0.0 1.4e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_6 PF14259.1 CDO74203.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO74203.1 - 0.00058 19.4 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2112 PF09885.4 CDO74203.1 - 0.057 13.0 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) Metallophos_2 PF12850.2 CDO74203.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF2397 PF09660.5 CDO74203.1 - 0.43 9.1 6.0 0.73 8.3 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) MMR1 PF08505.5 CDO74203.1 - 1.2 9.1 10.3 2.2 8.2 7.1 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RR_TM4-6 PF06459.7 CDO74203.1 - 3.5 7.4 9.9 5.5 6.7 6.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med13_C PF06333.7 CDO74204.1 - 1.6e-16 59.9 0.7 2e-15 56.3 0.1 2.3 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal MerR PF00376.18 CDO74204.1 - 0.34 10.5 1.7 0.53 9.8 0.0 2.2 3 0 0 3 3 3 0 MerR family regulatory protein Cerato-platanin PF07249.7 CDO74205.1 - 1.7e-47 160.3 0.5 2e-47 160.0 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin Plant_tran PF04827.9 CDO74205.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein Cerato-platanin PF07249.7 CDO74206.1 - 2.5e-48 162.9 0.9 3e-48 162.7 0.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 CDO74206.1 - 0.0062 16.1 0.2 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 Barwin family Plant_tran PF04827.9 CDO74206.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein Acyl-CoA_dh_1 PF00441.19 CDO74207.1 - 2.2e-42 144.6 3.3 3.6e-42 143.9 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CDO74207.1 - 5e-31 107.6 0.5 2.6e-30 105.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CDO74207.1 - 3.6e-20 71.2 0.0 6.7e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CDO74207.1 - 3.3e-18 66.2 2.5 5.3e-18 65.5 1.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CDO74207.1 - 0.00029 21.1 0.0 0.00054 20.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Mito_carr PF00153.22 CDO74208.1 - 8.5e-37 124.7 3.3 2.7e-18 65.4 0.5 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 CDO74208.1 - 0.0053 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like UcrQ PF02939.11 CDO74208.1 - 0.074 12.8 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 UcrQ family COX5A PF02284.11 CDO74209.1 - 0.022 14.6 0.2 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va KxDL PF10241.4 CDO74209.1 - 0.28 11.1 5.0 1.3 8.9 0.2 3.7 4 0 0 4 4 4 0 Uncharacterized conserved protein ATP-synt_S1 PF05827.7 CDO74210.1 - 5.6e-18 65.2 1.2 7.1e-13 48.5 0.1 2.0 1 1 1 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) Spt4 PF06093.8 CDO74211.1 - 8.7e-31 105.6 0.2 1.1e-30 105.3 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger OKR_DC_1_C PF03711.10 CDO74211.1 - 0.075 13.0 0.0 0.092 12.8 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain RAI1 PF08652.6 CDO74212.1 - 2.4e-21 75.2 0.0 7.6e-21 73.6 0.0 1.9 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Lipase_3 PF01764.20 CDO74213.1 - 7.5e-13 48.3 0.0 4.2e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_5 PF12695.2 CDO74213.1 - 0.047 13.4 0.1 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF336 PF03928.9 CDO74214.1 - 2.3e-19 69.5 0.0 2.8e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) PV-1 PF06637.6 CDO74215.1 - 0.037 12.6 7.9 0.049 12.1 5.5 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) MRI PF15325.1 CDO74217.1 - 1.2 10.1 3.0 0.39 11.7 0.2 1.6 2 0 0 2 2 2 0 Modulator of retrovirus infection UBN2_3 PF14244.1 CDO74218.1 - 8.3e-09 35.1 0.1 9.3e-09 35.0 0.1 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO74218.1 - 2.3e-06 26.8 0.7 2.3e-06 26.8 0.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Bombolitin PF08096.6 CDO74218.1 - 0.15 12.1 0.2 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Bombolitin family COesterase PF00135.23 CDO74219.1 - 2.8e-10 39.5 0.0 3.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family PS_Dcarbxylase PF02666.10 CDO74221.1 - 8.8e-12 44.7 0.0 1.3e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Dna2 PF08696.6 CDO74222.1 - 8.8e-51 172.1 0.0 1.7e-50 171.2 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 CDO74222.1 - 3e-50 170.4 0.0 4.8e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDO74222.1 - 6.9e-39 133.8 0.2 8.4e-20 71.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 CDO74222.1 - 7.2e-14 51.8 0.0 1.8e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO74222.1 - 1.8e-09 37.2 2.5 3.4e-09 36.3 0.1 2.7 3 0 0 3 3 2 1 Part of AAA domain Helicase_RecD PF05127.9 CDO74222.1 - 5.2e-05 22.9 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Helicase Cas_Cas4 PF01930.12 CDO74222.1 - 0.00032 20.6 0.1 0.0028 17.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 CDO74222.1 - 0.00032 20.2 0.1 0.39 10.1 0.0 3.4 2 1 1 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 CDO74222.1 - 0.00041 20.3 0.0 0.0015 18.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CDO74222.1 - 0.001 19.2 0.0 0.0029 17.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CDO74222.1 - 0.0018 17.3 0.0 0.004 16.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 CDO74222.1 - 0.0019 17.5 0.1 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 CDO74222.1 - 0.0023 16.9 0.1 0.02 13.8 0.0 2.0 1 1 0 1 1 1 1 PIF1-like helicase MobB PF03205.9 CDO74222.1 - 0.0036 17.0 0.8 0.0079 15.9 0.2 1.8 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 CDO74222.1 - 0.0061 15.8 0.0 0.05 12.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ArgK PF03308.11 CDO74222.1 - 0.014 14.2 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 ArgK protein DUF87 PF01935.12 CDO74222.1 - 0.019 14.7 0.3 0.04 13.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 T2SE PF00437.15 CDO74222.1 - 0.021 13.7 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 CDO74222.1 - 0.024 14.4 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CDO74222.1 - 0.028 13.8 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.10 CDO74222.1 - 0.035 13.9 0.2 0.084 12.6 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Miro PF08477.8 CDO74222.1 - 0.039 14.4 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 1 0 Miro-like protein SRP54 PF00448.17 CDO74222.1 - 0.039 13.3 0.4 0.065 12.6 0.3 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PASTA PF03793.14 CDO74222.1 - 0.063 12.9 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 PASTA domain AAA_29 PF13555.1 CDO74222.1 - 0.074 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 CDO74222.1 - 0.075 12.0 0.1 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 CDO74222.1 - 0.1 12.3 0.5 0.23 11.1 0.4 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 CDO74222.1 - 0.1 12.7 0.0 0.41 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CDO74222.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 CDO74222.1 - 0.16 11.3 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_15 PF13175.1 CDO74222.1 - 2.1 7.2 0.0 3.3 6.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain YL1_C PF08265.6 CDO74223.1 - 5.2e-14 51.4 0.2 9e-14 50.7 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CPL PF08144.6 CDO74224.1 - 2.7e-24 85.6 0.2 1.1e-22 80.5 0.0 3.4 3 1 1 4 4 4 1 CPL (NUC119) domain Osteopontin PF00865.13 CDO74225.1 - 4.2 6.5 12.7 6.8 5.8 8.8 1.2 1 0 0 1 1 1 0 Osteopontin COX4 PF02936.9 CDO74227.1 - 0.11 12.2 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV FadA PF09403.5 CDO74228.1 - 0.14 12.1 1.9 0.17 11.8 1.3 1.2 1 0 0 1 1 1 0 Adhesion protein FadA zf-CCHC PF00098.18 CDO74229.1 - 1.1e-06 28.2 2.7 1.7e-06 27.6 1.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CDO74229.1 - 2.1e-05 23.8 0.3 2.1e-05 23.8 0.2 1.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDO74229.1 - 0.0085 15.8 0.5 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.9 CDO74230.1 - 1.9e-85 285.7 0.0 2.7e-85 285.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO74230.1 - 1.1e-23 83.6 0.2 4.2e-23 81.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CDO74230.1 - 4.2e-09 35.9 0.3 9.8e-09 34.7 0.2 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 CDO74230.1 - 0.00024 20.6 0.0 0.0056 16.2 0.1 2.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 CDO74230.1 - 0.0022 17.4 0.0 0.0073 15.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CDO74230.1 - 0.019 14.3 0.0 0.27 10.5 0.0 2.4 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2 PF14223.1 CDO74230.1 - 0.046 13.5 0.1 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO74231.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.3 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO74231.1 - 0.015 14.7 0.9 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Asp-B-Hydro_N PF05279.6 CDO74232.1 - 4.5 7.0 16.5 5.3 6.8 11.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3513 PF12026.3 CDO74232.1 - 6.5 6.2 7.6 7.4 6.0 5.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) YqfQ PF14181.1 CDO74232.1 - 6.8 6.6 10.3 7.4 6.5 7.1 1.3 1 0 0 1 1 1 0 YqfQ-like protein Spore_coat_CotO PF14153.1 CDO74232.1 - 7.8 5.8 12.6 8.6 5.7 8.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO rve PF00665.21 CDO74233.1 - 1.5e-20 73.4 0.0 2.3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CDO74233.1 - 0.03 13.7 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Ferrochelatase PF00762.14 CDO74233.1 - 0.034 13.1 0.3 3.6 6.4 0.1 2.1 1 1 1 2 2 2 0 Ferrochelatase UBN_AB PF14075.1 CDO74234.1 - 0.07 12.7 0.1 0.07 12.7 0.0 1.6 2 0 0 2 2 2 0 Ubinuclein conserved middle domain FLO_LFY PF01698.11 CDO74234.1 - 6.3 5.5 7.5 4.5 6.0 1.2 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein Chromo PF00385.19 CDO74235.1 - 6.9e-08 32.0 0.1 1.2e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SelB-wing_2 PF09106.6 CDO74235.1 - 0.08 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix EcoR124_C PF12008.3 CDO74236.1 - 0.018 14.2 1.5 0.02 14.0 1.0 1.0 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Methyltransf_1N PF02870.10 CDO74236.1 - 0.068 13.7 0.3 0.088 13.4 0.2 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain FlxA PF14282.1 CDO74236.1 - 0.081 12.8 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 FlxA-like protein DUF972 PF06156.8 CDO74236.1 - 0.18 12.1 1.5 0.22 11.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) SPX PF03105.14 CDO74236.1 - 0.37 10.5 3.8 0.4 10.4 2.7 1.0 1 0 0 1 1 1 0 SPX domain DUF2457 PF10446.4 CDO74236.1 - 1.2 7.8 8.7 1.2 7.8 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) IncA PF04156.9 CDO74236.1 - 3.9 7.0 7.7 5 6.6 4.5 1.7 1 1 1 2 2 2 0 IncA protein INCA1 PF15142.1 CDO74237.1 - 0.16 11.7 0.9 21 4.8 0.0 2.6 2 1 0 2 2 2 0 INCA1 LRR_8 PF13855.1 CDO74237.1 - 0.21 11.3 0.9 5 6.9 0.1 3.0 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 CDO74237.1 - 0.35 10.5 8.0 0.64 9.7 0.1 4.0 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) NPBW PF15180.1 CDO74238.1 - 0.061 12.9 0.1 0.6 9.7 0.0 2.3 2 0 0 2 2 2 0 Neuropeptides B and W Aldedh PF00171.17 CDO74240.1 - 2.3e-51 174.5 0.0 5e-29 100.9 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family COPIIcoated_ERV PF07970.7 CDO74241.1 - 1.4e-35 122.9 0.9 2.4e-35 122.1 0.6 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CDO74241.1 - 1.5e-18 66.5 0.0 2.7e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) HTH_23 PF13384.1 CDO74243.1 - 0.00095 18.7 0.1 0.0021 17.6 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Adenine_glyco PF03352.8 CDO74243.1 - 0.18 11.3 0.2 4.6 6.7 0.1 2.2 2 0 0 2 2 2 0 Methyladenine glycosylase PepSY_2 PF13670.1 CDO74245.1 - 0.059 13.2 1.9 0.079 12.8 1.3 1.3 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain UPRTase PF14681.1 CDO74245.1 - 0.15 11.2 0.1 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF3669 PF12417.3 CDO74247.1 - 6.3e-09 35.4 0.2 1.4e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Zinc finger protein Cyt-b5 PF00173.23 CDO74248.1 - 6.8e-06 25.7 0.1 7.9e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MARVEL PF01284.18 CDO74249.1 - 1.3e-09 38.0 7.1 2e-09 37.3 4.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain MFS_2 PF13347.1 CDO74249.1 - 0.016 13.5 0.8 0.024 13.0 0.3 1.4 1 1 0 1 1 1 0 MFS/sugar transport protein Terpene_synth_C PF03936.11 CDO74251.1 - 1.6e-12 47.2 0.3 2.7e-12 46.5 0.2 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain RNA_pol_Rpb5_C PF01191.14 CDO74252.1 - 2.6e-35 119.8 0.1 5e-35 118.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CDO74252.1 - 1e-28 99.5 0.1 1.8e-28 98.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 CDO74252.1 - 0.00087 19.0 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease WD40 PF00400.27 CDO74253.1 - 7.3e-17 60.5 9.1 4.5e-06 26.3 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat TRAP_alpha PF03896.11 CDO74254.1 - 3.9e-05 22.8 0.0 0.00028 19.9 0.0 1.9 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit MitoNEET_N PF10660.4 CDO74254.1 - 0.0023 17.7 0.1 0.0048 16.7 0.1 1.5 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus Urease_beta PF00699.15 CDO74254.1 - 0.093 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Urease beta subunit FAM176 PF14851.1 CDO74255.1 - 0.014 15.1 1.1 0.02 14.5 0.8 1.4 1 0 0 1 1 1 0 FAM176 family DUF3536 PF12055.3 CDO74255.1 - 0.02 14.0 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) NDUFB10 PF10249.4 CDO74255.1 - 0.022 14.9 0.4 0.022 14.9 0.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Eaf7 PF07904.8 CDO74255.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 Transposase_21 PF02992.9 CDO74258.1 - 4.5e-06 25.9 0.0 8.6e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 zf-C2HC5 PF06221.8 CDO74258.1 - 1.7 8.4 4.6 2.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type RVT_1 PF00078.22 CDO74260.1 - 2.4e-18 66.3 0.1 5.2e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PEPCK_ATP PF01293.15 CDO74264.1 - 5.1e-218 724.2 0.0 6.1e-218 723.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DASH_Dad2 PF08654.5 CDO74264.1 - 1.2e-08 34.8 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 AAA_33 PF13671.1 CDO74264.1 - 0.0024 17.7 0.0 0.038 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CDO74264.1 - 0.0075 15.7 0.0 0.023 14.2 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CDO74264.1 - 0.011 15.7 0.5 0.063 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 CDO74264.1 - 0.055 14.2 0.1 0.31 11.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 CDO74264.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Strep_his_triad PF04270.8 CDO74264.1 - 0.13 11.9 0.6 0.46 10.2 0.4 2.0 1 0 0 1 1 1 0 Streptococcal histidine triad protein AAA_13 PF13166.1 CDO74264.1 - 0.13 10.6 0.4 0.27 9.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain Palm_thioest PF02089.10 CDO74265.1 - 3.5e-52 177.0 0.0 5.9e-52 176.3 0.0 1.3 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 CDO74265.1 - 0.0005 20.0 0.1 0.00064 19.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO74265.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DCAF15_WD40 PF14939.1 CDO74265.1 - 0.037 13.3 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat DUF915 PF06028.6 CDO74265.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_M1 PF01433.15 CDO74266.1 - 6.4e-95 318.5 0.0 2.9e-92 309.7 0.0 2.7 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CDO74266.1 - 1.5e-48 165.7 0.3 2e-48 165.2 0.2 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CDO74266.1 - 1.7e-08 34.5 0.1 4.7e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2460 PF09343.5 CDO74266.1 - 0.073 12.4 0.1 8.2 5.7 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical protein 2217 (DUF2460) Sad1_UNC PF07738.8 CDO74268.1 - 3.2e-20 72.2 0.0 4.6e-09 36.1 0.0 2.2 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal Transposase_21 PF02992.9 CDO74271.1 - 8.2e-19 67.5 0.0 1.5e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO74271.1 - 0.00044 19.7 0.0 0.00088 18.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Myb_DNA-bind_4 PF13837.1 CDO74272.1 - 2.3e-09 37.2 0.1 4.4e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO74272.1 - 6.5e-07 29.8 0.1 1e-06 29.2 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO74272.1 - 4e-05 23.4 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO74272.1 - 0.0066 16.5 0.1 0.018 15.1 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain CENP-B_dimeris PF09026.5 CDO74272.1 - 0.018 15.2 5.1 0.038 14.2 3.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myb_DNA-binding PF00249.26 CDO74272.1 - 0.16 12.0 1.6 0.38 10.8 0.6 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain Sigma70_ner PF04546.8 CDO74272.1 - 0.18 11.3 7.3 0.12 11.9 3.6 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region FUSC PF04632.7 CDO74272.1 - 0.2 10.0 0.3 0.23 9.8 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family RRN3 PF05327.6 CDO74272.1 - 0.21 9.6 0.7 0.29 9.2 0.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Myc_N PF01056.13 CDO74272.1 - 0.26 10.4 9.1 0.26 10.4 5.4 1.6 1 1 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 CDO74272.1 - 1.5 9.1 7.6 1.1 9.5 3.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Syntaxin_2 PF14523.1 CDO74273.1 - 1.9e-21 75.9 7.4 3e-21 75.3 1.7 2.6 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 CDO74273.1 - 1.5e-17 63.0 0.5 1.5e-17 63.0 0.3 2.0 2 0 0 2 2 2 1 SNARE domain DDE_Tnp_4 PF13359.1 CDO74273.1 - 1.1e-11 44.5 0.0 3.2e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.1 CDO74273.1 - 0.0001 22.4 0.2 0.0022 18.1 0.1 2.4 2 0 0 2 2 2 1 Transposase DDE domain Plant_tran PF04827.9 CDO74273.1 - 0.00011 21.7 0.1 0.0002 20.8 0.1 1.4 1 0 0 1 1 1 1 Plant transposon protein Syntaxin PF00804.20 CDO74273.1 - 0.00096 19.2 0.1 0.00096 19.2 0.1 2.8 1 1 1 3 3 3 1 Syntaxin RdRP_4 PF02123.11 CDO74273.1 - 0.077 11.6 0.2 0.13 10.9 0.1 1.4 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase DUF3317 PF11779.3 CDO74273.1 - 0.76 9.2 3.0 41 3.7 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) MCPsignal PF00015.16 CDO74273.1 - 3.1 7.2 12.1 0.36 10.3 2.9 2.8 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF202 PF02656.10 CDO74274.1 - 2.5e-20 72.4 2.5 2.5e-20 72.4 1.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MscS_TM PF12794.2 CDO74274.1 - 0.00044 18.9 4.7 0.00062 18.4 3.2 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 EH_Signature PF15611.1 CDO74274.1 - 0.016 14.2 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 EH_Signature domain SdpI PF13630.1 CDO74274.1 - 0.21 11.3 7.6 0.28 10.9 5.0 1.4 1 1 0 1 1 1 0 SdpI/YhfL protein family CD20 PF04103.10 CDO74274.1 - 0.69 9.8 14.1 0.098 12.5 0.7 3.0 3 0 0 3 3 3 0 CD20-like family DUF3784 PF12650.2 CDO74274.1 - 2.6 8.0 6.9 5 7.1 4.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) DUF1168 PF06658.7 CDO74275.1 - 0.23 10.9 10.9 0.26 10.7 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Spore_coat_CotO PF14153.1 CDO74275.1 - 1 8.7 14.5 1.1 8.7 10.0 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 CDO74275.1 - 1.1 7.6 10.9 1.2 7.5 7.6 1.0 1 0 0 1 1 1 0 Daxx Family zf-CCHC PF00098.18 CDO74276.1 - 3.4e-05 23.5 2.3 5.8e-05 22.8 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDO74276.1 - 0.048 13.3 0.3 0.094 12.4 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDO74276.1 - 0.076 12.6 0.6 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle CENP-F_leu_zip PF10473.4 CDO74277.1 - 0.0084 15.9 0.6 0.014 15.2 0.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1978 PF09321.5 CDO74277.1 - 0.031 13.7 1.8 0.051 13.0 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Dynamitin PF04912.9 CDO74277.1 - 0.16 10.7 0.2 0.24 10.1 0.2 1.2 1 0 0 1 1 1 0 Dynamitin CobT_C PF11775.3 CDO74278.1 - 0.087 12.2 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain rve PF00665.21 CDO74279.1 - 1.3e-22 80.1 0.2 4.3e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CDO74279.1 - 3.3e-09 36.2 0.3 7e-09 35.2 0.2 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 CDO74279.1 - 7.6e-09 35.1 0.1 1.7e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO74279.1 - 0.00078 19.2 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVT_2 PF07727.9 CDO74279.1 - 0.0015 17.5 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CDO74279.1 - 0.032 13.7 0.0 0.077 12.5 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain UBN2_3 PF14244.1 CDO74279.1 - 0.23 11.0 0.0 0.63 9.5 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Carboxyl_trans PF01039.17 CDO74280.1 - 1.2e-139 465.8 0.5 1.6e-139 465.4 0.3 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CDO74280.1 - 0.00062 19.0 0.1 0.013 14.7 0.0 2.3 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) WD40 PF00400.27 CDO74281.1 - 2.1e-08 33.7 2.7 0.00023 20.9 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1933 PF09147.5 CDO74281.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) DUF4597 PF15366.1 CDO74282.1 - 0.49 10.0 4.5 1.7 8.3 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4597) Mg_trans_NIPA PF05653.9 CDO74283.1 - 8.7e-61 205.4 6.4 3.1e-58 197.0 2.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 CDO74283.1 - 2.1e-05 24.6 1.0 2.1e-05 24.6 0.7 4.0 3 1 0 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 CDO74283.1 - 2.7e-05 24.2 2.9 2.7e-05 24.2 2.0 3.8 3 1 1 4 4 4 1 EamA-like transporter family DUF914 PF06027.7 CDO74283.1 - 0.063 12.1 1.6 0.064 12.0 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) WD40 PF00400.27 CDO74285.1 - 2.1e-13 49.5 0.1 6.3e-07 29.0 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat TFIID-31kDa PF02291.10 CDO74286.1 - 6.6e-29 100.3 0.0 1e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 CDO74286.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Kinetochore component CENP-S Histone PF00125.19 CDO74286.1 - 0.023 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 CDO74286.1 - 0.027 14.1 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated FMN_red PF03358.10 CDO74286.1 - 0.05 13.1 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 NADPH-dependent FMN reductase MBOAT PF03062.14 CDO74287.1 - 1.5e-39 136.0 2.5 2.5e-39 135.3 1.7 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SSB PF00436.20 CDO74288.1 - 7.1e-16 57.9 0.0 9.2e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family GTP_EFTU PF00009.22 CDO74289.1 - 3e-45 153.9 0.0 5.5e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 CDO74289.1 - 6.7e-15 54.9 2.1 1.6e-14 53.7 1.4 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 CDO74289.1 - 3.2e-05 24.0 0.0 0.00011 22.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 CDO74289.1 - 5.3e-05 23.1 0.0 0.00028 20.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CDO74289.1 - 0.0022 17.5 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 CDO74289.1 - 0.021 14.9 0.2 0.046 13.8 0.1 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Miro PF08477.8 CDO74289.1 - 0.032 14.7 0.0 0.43 11.0 0.0 2.5 1 1 0 1 1 1 0 Miro-like protein DUF3295 PF11702.3 CDO74290.1 - 0.094 11.6 0.7 0.31 9.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) UPF0270 PF06794.7 CDO74290.1 - 0.19 11.5 0.6 0.49 10.2 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Pkinase PF00069.20 CDO74292.1 - 0.0024 17.0 0.0 0.0029 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain MRI PF15325.1 CDO74293.1 - 0.15 13.0 0.3 0.3 12.0 0.2 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection UBN2 PF14223.1 CDO74294.1 - 4.6e-17 61.9 0.0 6.8e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CDO74294.1 - 2.7e-15 55.9 0.0 4.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO74294.1 - 2.1e-10 40.3 0.0 4.3e-10 39.3 0.0 1.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO74294.1 - 1.4e-06 27.9 3.4 2.3e-06 27.2 2.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDO74294.1 - 0.059 13.1 1.5 0.14 11.9 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle TNFR_c6 PF00020.13 CDO74294.1 - 0.075 13.1 2.1 0.14 12.2 1.5 1.4 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region RVT_1 PF00078.22 CDO74296.1 - 8.4e-15 54.7 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 CDO74296.1 - 7.2e-08 32.4 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CDO74296.1 - 4.9e-07 30.1 0.0 8.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO74296.1 - 3.3e-06 26.8 0.0 7.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 CDO74296.1 - 0.0089 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase Retrotrans_gag PF03732.12 CDO74297.1 - 3.8e-05 23.6 0.0 7.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF605 PF04652.11 CDO74297.1 - 9.7 5.4 9.8 11 5.2 6.8 1.1 1 0 0 1 1 1 0 Vta1 like UBN2 PF14223.1 CDO74298.1 - 6.7e-18 64.5 0.0 1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CDO74298.1 - 9.8e-18 63.8 0.0 1.6e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO74298.1 - 1.6e-07 30.9 2.8 2.8e-07 30.1 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle UBN2_3 PF14244.1 CDO74298.1 - 0.0035 16.9 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.1 CDO74298.1 - 0.0042 16.7 0.4 0.01 15.5 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CDO74298.1 - 0.016 14.6 1.2 0.034 13.6 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDO74298.1 - 0.45 10.2 1.9 0.84 9.3 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle RNase_H PF00075.19 CDO74300.1 - 0.00026 21.3 0.0 0.00032 21.0 0.0 1.2 1 0 0 1 1 1 1 RNase H Torsin PF06309.6 CDO74300.1 - 0.049 13.5 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Torsin OPT PF03169.10 CDO74303.1 - 9e-139 463.7 26.7 1.1e-138 463.4 18.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Lysis_S PF04971.7 CDO74303.1 - 0.49 10.1 6.1 9.9 5.9 0.2 3.4 3 0 0 3 3 3 0 Lysis protein S YchF-GTPase_C PF06071.8 CDO74304.1 - 8.8e-36 121.5 0.0 2e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CDO74304.1 - 6.3e-14 51.9 0.0 1.9e-13 50.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDO74304.1 - 2.9e-05 23.4 0.0 5.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B BetaGal_dom3 PF13363.1 CDO74304.1 - 0.01 15.2 0.2 0.66 9.4 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 AAA_17 PF13207.1 CDO74304.1 - 0.013 16.2 0.1 0.082 13.7 0.1 2.5 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 CDO74304.1 - 0.058 12.1 0.3 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 ArgK protein AD PF09793.4 CDO74304.1 - 0.1 12.4 0.8 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 Anticodon-binding domain RPAP1_N PF08621.5 CDO74304.1 - 0.16 11.5 2.6 0.31 10.6 1.8 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal 4HBT PF03061.17 CDO74306.1 - 0.0013 18.7 0.1 0.0034 17.4 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily TauD PF02668.11 CDO74307.1 - 1.9e-54 185.0 0.1 2.6e-54 184.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EF-hand_1 PF00036.27 CDO74308.1 - 8.6e-27 90.3 15.7 4e-09 35.1 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDO74308.1 - 9.9e-25 86.4 13.3 3.3e-12 46.3 1.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CDO74308.1 - 3.8e-23 79.2 12.7 1.4e-08 33.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CDO74308.1 - 8.2e-16 56.5 7.6 8.6e-05 21.6 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CDO74308.1 - 2.4e-15 55.8 15.8 9.9e-10 37.8 1.1 3.8 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 CDO74308.1 - 1.8e-09 37.3 0.8 0.0011 18.8 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CDO74308.1 - 3.2e-09 36.4 6.4 0.00014 21.5 0.1 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 CDO74308.1 - 0.016 14.8 0.1 0.24 10.9 0.0 2.3 2 1 0 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.4 CDO74308.1 - 0.024 14.6 3.0 0.64 10.0 0.1 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1636 PF07845.6 CDO74308.1 - 0.078 13.2 0.0 2.5 8.3 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1636) DUF1059 PF06348.6 CDO74308.1 - 0.1 12.4 0.2 0.6 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) MgtE_N PF03448.12 CDO74308.1 - 1.7 9.0 6.5 0.5 10.7 1.2 2.3 3 0 0 3 3 3 0 MgtE intracellular N domain zf-C2H2 PF00096.21 CDO74309.1 - 2.4e-09 36.9 13.6 0.00016 21.7 1.3 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO74309.1 - 1.7e-07 31.0 7.3 0.0015 18.7 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CDO74309.1 - 7.6e-07 29.1 3.8 7.6e-07 29.1 2.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 CDO74309.1 - 0.0012 18.6 0.7 0.0032 17.2 0.5 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger Retrotrans_gag PF03732.12 CDO74310.1 - 1.3e-12 47.6 0.1 4.4e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO74310.1 - 0.013 15.4 0.3 0.02 14.8 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle UBN2 PF14223.1 CDO74310.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Macoilin PF09726.4 CDO74310.1 - 2.9 6.0 9.3 4.2 5.5 6.4 1.1 1 0 0 1 1 1 0 Transmembrane protein SEEEED PF14797.1 CDO74311.1 - 8.3 6.5 17.8 2.3 8.3 8.8 2.0 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Surp PF01805.15 CDO74312.1 - 0.039 13.5 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Surp module FAM176 PF14851.1 CDO74312.1 - 1.8 8.1 7.6 5 6.8 0.2 2.6 2 1 0 2 2 2 0 FAM176 family Piwi PF02171.12 CDO74313.1 - 5.2e-73 245.6 0.0 7.7e-73 245.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CDO74313.1 - 1.7e-16 59.7 0.0 3e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CDO74313.1 - 1.2e-13 50.1 0.2 3.1e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) LRR_6 PF13516.1 CDO74314.1 - 0.00033 20.4 0.1 4.9 7.5 0.0 4.1 4 1 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 CDO74314.1 - 0.00067 19.2 0.0 2.8 7.6 0.0 3.8 3 2 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDO74314.1 - 0.0033 17.2 0.6 9.6 6.6 0.0 4.1 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 CDO74314.1 - 0.091 13.0 7.1 7.6 7.2 0.2 4.5 5 0 0 5 5 5 0 Leucine rich repeat Phage_Gp111 PF07410.6 CDO74314.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 1 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein UBN2_2 PF14227.1 CDO74315.1 - 2.9e-16 59.1 0.0 6.1e-16 58.0 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO74315.1 - 1.9e-11 43.7 0.0 2.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO74315.1 - 0.00022 20.7 0.2 0.00053 19.5 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain BRF1 PF07741.8 CDO74315.1 - 7.3 6.8 6.6 9.7 6.4 1.0 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Ribosomal_S5 PF00333.15 CDO74317.1 - 6.8e-28 96.2 1.5 6.8e-28 96.2 1.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CDO74317.1 - 9.4e-22 76.0 0.0 1.6e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Fungal_trans PF04082.13 CDO74319.1 - 4.6e-24 84.6 0.1 2.4e-20 72.5 0.0 2.7 3 0 0 3 3 3 2 Fungal specific transcription factor domain Glyco_hydro_10 PF00331.15 CDO74320.1 - 3.5e-66 223.4 0.0 8.2e-60 202.4 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 Arginase PF00491.16 CDO74321.1 - 6.2e-71 238.9 0.0 7.6e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family Asp PF00026.18 CDO74322.1 - 2.3e-28 99.3 1.8 2.6e-28 99.1 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF2013 PF09431.5 CDO74325.1 - 8.6e-33 113.0 2.0 1.8e-32 112.0 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) zf-B_box PF00643.19 CDO74326.1 - 0.0051 16.6 4.1 0.012 15.4 2.8 1.5 1 0 0 1 1 1 1 B-box zinc finger Cauli_VI PF01693.11 CDO74327.1 - 7.2e-07 29.1 0.4 1.8e-06 27.8 0.1 1.8 2 0 0 2 2 2 1 Caulimovirus viroplasmin FlgI PF02119.11 CDO74328.1 - 0.12 10.9 0.2 0.18 10.3 0.1 1.1 1 0 0 1 1 1 0 Flagellar P-ring protein ABC_tran PF00005.22 CDO74329.1 - 6.4e-47 159.2 0.0 6.6e-28 97.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CDO74329.1 - 1.3e-40 139.5 21.2 6.9e-22 78.1 6.2 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 CDO74329.1 - 1.5e-11 44.8 2.2 0.031 14.2 0.2 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 CDO74329.1 - 1.8e-10 40.4 6.0 0.018 14.2 1.0 4.6 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CDO74329.1 - 1.9e-08 33.9 0.3 0.00083 18.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CDO74329.1 - 2.3e-07 31.3 3.3 0.00015 22.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CDO74329.1 - 1.4e-06 27.6 4.6 0.014 14.8 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CDO74329.1 - 2e-06 27.9 2.0 0.0082 16.1 0.7 2.7 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 CDO74329.1 - 7.5e-06 25.0 0.1 0.085 11.7 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_17 PF13207.1 CDO74329.1 - 2.2e-05 25.2 0.7 0.096 13.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CDO74329.1 - 9.1e-05 22.3 0.1 0.13 12.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CDO74329.1 - 0.00012 21.5 0.0 0.095 12.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 CDO74329.1 - 0.00016 21.5 0.6 0.0099 15.7 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 CDO74329.1 - 0.00017 22.0 0.0 0.34 11.4 0.0 3.3 2 1 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CDO74329.1 - 0.00019 21.5 1.3 0.6 10.2 0.0 3.5 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 CDO74329.1 - 0.00023 20.9 0.5 0.17 11.6 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CDO74329.1 - 0.00028 20.1 0.0 0.17 11.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CDO74329.1 - 0.00046 19.7 1.9 0.96 8.8 0.1 3.5 2 1 0 3 3 3 1 AAA-like domain AAA_18 PF13238.1 CDO74329.1 - 0.00098 19.4 0.0 0.88 9.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CDO74329.1 - 0.002 17.5 0.4 2.4 7.5 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CDO74329.1 - 0.0043 16.1 0.0 0.4 9.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 CDO74329.1 - 0.008 15.9 0.4 2.9 7.7 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain Adeno_IVa2 PF02456.10 CDO74329.1 - 0.015 14.0 0.2 0.11 11.1 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 CDO74329.1 - 0.021 14.5 0.1 0.46 10.1 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase AAA_33 PF13671.1 CDO74329.1 - 0.023 14.5 0.0 3.6 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 CDO74329.1 - 0.033 13.7 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CDO74329.1 - 0.042 13.5 0.4 20 4.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 CDO74329.1 - 0.044 13.2 0.0 5.3 6.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 CDO74329.1 - 0.046 13.6 0.1 4.4 7.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.10 CDO74329.1 - 0.047 13.4 0.2 0.28 10.8 0.0 2.4 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 CDO74329.1 - 0.064 12.7 1.6 2.6 7.5 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.7 CDO74329.1 - 0.064 12.5 0.7 7.2 5.8 0.0 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.18 CDO74329.1 - 0.07 12.9 0.1 4.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Dynamin family ResIII PF04851.10 CDO74329.1 - 0.087 12.6 0.0 6.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit cobW PF02492.14 CDO74329.1 - 0.095 12.1 1.8 2.6 7.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 CDO74329.1 - 0.2 11.8 0.0 17 5.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 CDO74329.1 - 0.21 11.2 1.5 14 5.3 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.1 CDO74329.1 - 0.46 9.4 0.0 0.98 8.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Macoilin PF09726.4 CDO74329.1 - 9.8 4.3 7.6 17 3.5 5.2 1.2 1 0 0 1 1 1 0 Transmembrane protein BTB PF00651.26 CDO74330.1 - 5.8e-05 23.0 0.0 9.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 CDO74331.1 - 0.0027 17.6 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Proteasome PF00227.21 CDO74332.1 - 1.3e-38 132.2 0.0 1.5e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Matrilin_ccoil PF10393.4 CDO74332.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin BTB PF00651.26 CDO74333.1 - 0.018 15.0 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain WD40 PF00400.27 CDO74334.1 - 7.3e-30 101.7 10.0 1.5e-07 31.0 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CDO74334.1 - 9.8e-09 35.1 0.1 2e-05 24.4 0.0 3.8 1 1 4 5 5 5 1 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 CDO74334.1 - 0.0023 17.6 1.8 0.3 10.7 0.0 2.4 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term HMA PF00403.21 CDO74336.1 - 0.22 11.7 1.1 2.2 8.4 0.0 2.3 1 1 1 2 2 2 0 Heavy-metal-associated domain BTB PF00651.26 CDO74337.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF775 PF05603.7 CDO74338.1 - 1.4e-46 158.5 0.0 1.7e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) WD40 PF00400.27 CDO74341.1 - 1e-35 120.3 12.3 1.9e-09 37.0 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Aminotran_1_2 PF00155.16 CDO74342.1 - 3.8e-38 131.3 0.0 5.6e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CDO74342.1 - 0.024 13.7 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase HMGL-like PF00682.14 CDO74344.1 - 7.4e-42 143.6 0.0 1.4e-41 142.7 0.0 1.4 1 1 0 1 1 1 1 HMGL-like Gelsolin PF00626.17 CDO74347.1 - 0.0019 17.8 0.0 0.27 10.9 0.0 3.0 3 0 0 3 3 3 2 Gelsolin repeat Glyco_hydro_16 PF00722.16 CDO74348.1 - 3.8e-08 32.8 0.0 7.3e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 FAD_binding_3 PF01494.14 CDO74349.1 - 4.2e-31 108.2 0.0 6.3e-31 107.7 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CDO74349.1 - 0.00021 20.3 0.0 0.028 13.3 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CDO74349.1 - 0.026 14.9 0.0 5.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO74349.1 - 0.039 13.9 0.1 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDO74349.1 - 0.064 13.1 0.1 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 CDO74349.1 - 0.084 11.6 0.0 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pro-kuma_activ PF09286.6 CDO74350.1 - 9.2e-38 129.5 0.2 3.8e-36 124.2 0.0 2.6 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO74350.1 - 3.3e-10 39.5 4.8 5.2e-10 38.9 3.3 1.2 1 0 0 1 1 1 1 Subtilase family RVT_2 PF07727.9 CDO74351.1 - 2.5e-89 298.4 0.1 4.2e-89 297.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) P34-Arc PF04045.9 CDO74354.1 - 1.9e-100 335.1 0.1 2.3e-100 334.8 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Homeobox PF00046.24 CDO74355.1 - 1.3e-19 69.5 2.9 2.1e-19 68.9 2.0 1.3 1 0 0 1 1 1 1 Homeobox domain RRM_1 PF00076.17 CDO74356.1 - 7.1e-19 67.2 0.1 1.4e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO74356.1 - 4e-17 61.9 0.1 5.9e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO74356.1 - 3.7e-10 39.4 0.0 9e-10 38.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 CDO74356.1 - 0.82 10.0 7.0 1.4 9.3 4.8 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal UbiA PF01040.13 CDO74357.1 - 1.4e-29 103.1 16.0 2.5e-29 102.3 11.1 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Citrate_synt PF00285.16 CDO74358.1 - 1.7e-89 300.0 0.0 2.4e-89 299.5 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase Methyltransf_4 PF02390.12 CDO74359.1 - 2.7e-54 183.2 0.0 3.4e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CDO74359.1 - 0.00016 22.2 0.0 0.00029 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO74359.1 - 0.0038 17.2 0.0 0.0083 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO74359.1 - 0.0081 16.5 0.0 0.029 14.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO74359.1 - 0.038 14.4 0.0 0.44 11.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CDO74359.1 - 0.16 12.4 0.0 0.53 10.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PqqA PF08042.6 CDO74359.1 - 0.16 11.6 0.4 0.9 9.2 0.1 2.2 2 0 0 2 2 2 0 PqqA family RNase_PH PF01138.16 CDO74360.1 - 2.6e-36 124.8 0.1 5e-36 123.9 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CDO74360.1 - 0.00047 20.0 0.0 0.00096 19.0 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NAPRTase PF04095.11 CDO74361.1 - 6.9e-60 202.3 0.0 9.1e-60 201.9 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family SH3_9 PF14604.1 CDO74362.1 - 9.7e-14 50.6 0.1 1.6e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CDO74362.1 - 1.7e-13 49.7 0.1 2.4e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CDO74362.1 - 1.4e-11 43.7 0.0 2.6e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.4 CDO74362.1 - 1 9.3 6.8 0.27 11.2 2.5 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Voldacs PF03517.8 CDO74363.1 - 4.8e-28 97.6 0.1 4.8e-28 97.6 0.1 1.9 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling ORF11CD3 PF10549.4 CDO74364.1 - 0.014 15.1 0.1 0.04 13.6 0.1 1.7 1 0 0 1 1 1 0 ORF11CD3 domain BBS2_Mid PF14783.1 CDO74364.1 - 0.29 10.9 0.0 0.55 10.0 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region DUF342 PF03961.8 CDO74364.1 - 1.2 7.4 4.1 2.5 6.4 2.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CorA PF01544.13 CDO74364.1 - 1.4 7.8 1.6 2.8 6.8 1.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Exo_endo_phos PF03372.18 CDO74365.1 - 4.4e-12 46.4 0.0 1.5e-09 38.1 0.0 2.4 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family COX6B PF02297.12 CDO74366.1 - 7.4e-17 61.1 5.7 7.4e-17 61.1 4.0 1.8 1 1 1 2 2 2 1 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 CDO74366.1 - 2 8.3 6.5 11 5.9 0.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Prp18 PF02840.10 CDO74367.1 - 3e-56 189.2 0.3 3e-56 189.2 0.2 2.3 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 CDO74367.1 - 1.3e-12 46.7 5.9 4.8e-12 44.9 4.1 2.1 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like MCPVI PF02993.9 CDO74367.1 - 1.1 9.3 12.4 3.3 7.8 2.3 2.3 2 0 0 2 2 2 0 Minor capsid protein VI BORG_CEP PF14957.1 CDO74367.1 - 3.8 8.4 10.7 8.8 7.2 2.3 2.5 2 0 0 2 2 2 0 Cdc42 effector Retrotrans_gag PF03732.12 CDO74368.1 - 2.6e-11 43.4 0.1 8e-11 41.8 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Macoilin PF09726.4 CDO74368.1 - 1.2 7.3 5.6 1.8 6.7 3.9 1.2 1 0 0 1 1 1 0 Transmembrane protein RVP_2 PF08284.6 CDO74369.1 - 7.3e-08 32.4 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CDO74369.1 - 8e-08 32.6 0.0 1.7e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO74369.1 - 2.5e-06 27.2 0.0 7.3e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 CDO74369.1 - 0.00041 19.7 0.0 0.00066 19.0 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase Peptidase_A3 PF02160.10 CDO74369.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) RVT_1 PF00078.22 CDO74370.1 - 3.8e-17 62.3 0.0 1.1e-16 60.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO74370.1 - 0.072 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO74371.1 - 3.7e-15 56.0 0.0 8e-15 55.0 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain DDE_2 PF02914.10 CDO74371.1 - 0.017 14.6 0.0 0.92 8.9 0.0 2.2 1 1 1 2 2 2 0 Bacteriophage Mu transposase IGPD PF00475.13 CDO74371.1 - 0.022 14.5 0.5 0.055 13.3 0.0 1.8 2 0 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase COMP PF11598.3 CDO74371.1 - 0.13 12.3 0.4 0.23 11.5 0.3 1.4 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein APH PF01636.18 CDO74372.1 - 0.00011 22.0 0.3 0.00015 21.5 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HET PF06985.6 CDO74373.1 - 3.3e-20 72.6 9.9 1.7e-17 63.8 2.5 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) 7tm_7 PF08395.7 CDO74373.1 - 0.14 11.1 0.8 0.22 10.4 0.5 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor Lectin_leg-like PF03388.8 CDO74374.1 - 3.6e-65 219.3 0.1 4.6e-65 218.9 0.1 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 CDO74374.1 - 1.6e-05 24.3 0.0 0.069 12.5 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain adh_short PF00106.20 CDO74375.1 - 5.2e-24 85.0 0.0 7e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO74375.1 - 5.3e-09 36.0 0.0 7.5e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CDO74375.1 - 1.6e-05 24.8 0.0 2.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 CDO74375.1 - 0.0054 16.2 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CDO74375.1 - 0.023 14.7 0.0 0.058 13.3 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding adh_short PF00106.20 CDO74376.1 - 1.6e-24 86.7 0.1 2e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO74376.1 - 7.4e-10 38.7 0.0 9.7e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO74376.1 - 6.4e-07 29.0 0.0 8.7e-07 28.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 CDO74376.1 - 1.3e-05 25.1 0.0 1.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CDO74376.1 - 0.0012 18.9 0.1 0.0022 18.0 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Zeta_toxin PF06414.7 CDO74376.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Polysacc_synt_2 PF02719.10 CDO74376.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 CDO74376.1 - 0.063 12.1 0.1 0.55 9.1 0.1 2.1 1 1 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.12 CDO74376.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 CDO74376.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.20 CDO74378.1 - 0.054 12.6 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pan_kinase PF03309.9 CDO74378.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Type III pantothenate kinase HNH_2 PF13391.1 CDO74379.1 - 0.00022 20.9 0.0 0.00044 19.9 0.0 1.5 1 1 0 1 1 1 1 HNH endonuclease EF_assoc_2 PF08356.7 CDO74379.1 - 0.07 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 EF hand associated RAP1 PF07218.6 CDO74380.1 - 3.6 5.5 4.7 4.5 5.2 3.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ETF_QO PF05187.8 CDO74381.1 - 0.00021 21.2 0.1 0.00051 20.0 0.0 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase MULE PF10551.4 CDO74382.1 - 1.5e-12 47.4 0.0 3e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Cytochrom_c3_2 PF14537.1 CDO74382.1 - 0.037 14.3 4.6 0.091 13.1 3.2 1.6 1 0 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 CDO74382.1 - 0.16 11.6 4.2 0.32 10.6 2.9 1.5 1 0 0 1 1 1 0 Cytochrome c7 ETF_QO PF05187.8 CDO74384.1 - 0.013 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase PHD PF00628.24 CDO74387.1 - 0.012 15.2 7.2 0.022 14.4 2.7 2.4 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.20 CDO74389.1 - 5.4e-20 71.6 0.0 6.5e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74389.1 - 2.5e-08 33.3 0.0 2.9e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.2 CDO74390.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 CDO74390.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 F-box domain Tetraspannin PF00335.15 CDO74391.1 - 0.0016 17.7 8.4 0.0016 17.7 5.8 2.0 1 1 1 2 2 2 1 Tetraspanin family MtmB PF05369.7 CDO74391.1 - 0.15 10.1 0.2 0.19 9.8 0.2 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB SKN1 PF03935.10 CDO74392.1 - 3.5e-184 612.6 8.9 3.5e-184 612.6 6.1 1.4 1 1 1 2 2 2 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hyd_65N_2 PF14498.1 CDO74394.1 - 0.049 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Ank PF00023.25 CDO74397.1 - 0.00014 21.4 0.2 0.00014 21.4 0.2 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CDO74397.1 - 0.00084 19.5 0.1 0.0038 17.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CDO74397.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.4 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDO74397.1 - 0.021 15.3 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO74397.1 - 0.024 14.8 0.2 0.078 13.2 0.1 1.9 2 0 0 2 2 2 0 Ankyrin repeat Mating_N PF12731.2 CDO74398.1 - 0.094 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Mating-type protein beta 1 NUDIX PF00293.23 CDO74399.1 - 3.1e-10 39.8 0.0 5.5e-10 39.0 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain Cupin_5 PF06172.6 CDO74400.1 - 3.5e-21 75.5 0.0 4.3e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) RVT_2 PF07727.9 CDO74401.1 - 4.3e-77 258.3 0.0 6e-77 257.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO74401.1 - 4.6e-22 78.3 0.0 1.4e-21 76.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CDO74401.1 - 9.3e-08 31.6 0.1 2.2e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 GAG-pre-integrase domain UBN2_2 PF14227.1 CDO74401.1 - 1.4e-06 27.8 0.0 2.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO74401.1 - 9.8e-05 22.1 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO74401.1 - 0.002 17.9 3.6 0.004 17.0 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2_3 PF14244.1 CDO74401.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type CP12 PF02672.10 CDO74401.1 - 0.088 13.2 2.2 0.26 11.8 0.2 2.8 2 0 0 2 2 2 0 CP12 domain SDA1 PF05285.7 CDO74402.1 - 0.13 11.5 7.3 0.17 11.1 5.1 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 CDO74402.1 - 4.3 5.1 9.9 6.3 4.5 6.9 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CDO74403.1 - 0.0034 15.9 9.5 0.0037 15.8 6.6 1.0 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 CDO74403.1 - 1.3 6.9 6.4 1.5 6.7 4.5 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 CDO74403.1 - 4.1 6.5 11.4 4.5 6.4 7.9 1.0 1 0 0 1 1 1 0 SDA1 Enolase_C PF00113.17 CDO74405.1 - 4e-147 488.8 0.1 5.5e-147 488.4 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CDO74405.1 - 1.6e-57 193.0 0.1 2.8e-57 192.3 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CDO74405.1 - 1.3e-05 25.1 0.1 3.9e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 CDO74405.1 - 0.0014 17.6 0.1 0.0034 16.3 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 CDO74405.1 - 0.026 15.0 0.0 0.068 13.7 0.0 1.8 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain PAP_assoc PF03828.14 CDO74406.1 - 4.2e-14 52.2 0.0 8.3e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CDO74406.1 - 3.6e-07 30.4 0.0 6.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Glyco_hydro_20 PF00728.17 CDO74407.1 - 1.3e-36 126.5 0.0 5.4e-36 124.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 CDO74407.1 - 1.8e-08 34.9 0.0 8.1e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Lipase_GDSL_2 PF13472.1 CDO74408.1 - 6.6e-17 62.2 1.4 1.1e-16 61.4 1.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CDO74408.1 - 4.4e-12 46.3 0.9 1e-11 45.1 0.6 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ribosomal_S4 PF00163.14 CDO74409.1 - 1.1e-26 92.9 0.8 2.3e-26 92.0 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CDO74409.1 - 4.1e-12 45.3 1.5 4.1e-12 45.3 1.0 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 CDO74410.1 - 5.9e-39 131.8 4.1 9.3e-39 131.2 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_replicase_B PF03431.8 CDO74410.1 - 0.015 13.5 0.2 0.017 13.3 0.1 1.0 1 0 0 1 1 1 0 RNA replicase, beta-chain 2Fe-2S_Ferredox PF11591.3 CDO74412.1 - 0.45 10.2 2.6 1.3 8.7 1.8 1.8 1 1 0 1 1 1 0 Ferredoxin chloroplastic transit peptide TIP49 PF06068.8 CDO74413.1 - 9.4e-180 597.5 0.8 1.1e-179 597.3 0.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CDO74413.1 - 4.8e-09 36.5 0.1 9.5e-06 25.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDO74413.1 - 4.9e-06 25.7 1.0 0.0048 15.9 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CDO74413.1 - 0.00062 18.9 2.1 0.016 14.3 0.2 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CDO74413.1 - 0.00079 19.4 0.0 0.01 15.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.10 CDO74413.1 - 0.0008 18.3 0.1 0.0014 17.5 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 CDO74413.1 - 0.00082 19.5 0.1 0.16 12.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CDO74413.1 - 0.00094 18.6 0.9 0.011 15.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CDO74413.1 - 0.013 15.2 0.2 5.2 6.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TFIID_20kDa PF03847.8 CDO74413.1 - 0.024 14.8 0.3 0.067 13.4 0.2 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Sipho_tail PF05709.6 CDO74413.1 - 0.032 13.3 0.6 0.081 12.0 0.0 1.9 2 0 0 2 2 2 0 Phage tail protein Ribosomal_L2_C PF03947.13 CDO74414.1 - 8.5e-50 167.9 1.2 1.4e-49 167.2 0.9 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CDO74414.1 - 8.4e-27 92.9 0.1 1.7e-26 91.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF4268 PF14088.1 CDO74415.1 - 0.038 13.6 0.2 0.055 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Ribophorin_I PF04597.9 CDO74415.1 - 0.057 11.9 0.0 0.084 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribophorin I Methyltransf_16 PF10294.4 CDO74416.1 - 1e-18 67.3 0.0 1.5e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CDO74416.1 - 7.4e-10 39.4 0.0 1.5e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO74416.1 - 3.4e-07 30.6 0.0 7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CDO74416.1 - 7.7e-07 28.5 0.0 1.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 CDO74416.1 - 9.1e-06 25.3 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO74416.1 - 1.3e-05 24.9 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO74416.1 - 2.2e-05 24.8 0.0 8.5e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CDO74416.1 - 4.4e-05 22.9 0.0 8.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CDO74416.1 - 7.4e-05 22.7 0.1 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CDO74416.1 - 0.00094 18.7 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 CDO74416.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.1 CDO74416.1 - 0.065 13.5 0.0 0.51 10.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF938 PF06080.7 CDO74416.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Homeobox PF00046.24 CDO74417.1 - 1.5e-14 53.3 4.0 3e-14 52.3 2.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CDO74417.1 - 0.00026 20.6 0.0 0.00066 19.3 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Histone PF00125.19 CDO74419.1 - 6.4e-30 103.1 0.8 1e-29 102.4 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CDO74419.1 - 2e-05 24.7 0.1 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CDO74419.1 - 0.00057 19.8 0.6 0.002 18.1 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CDO74419.1 - 0.021 14.5 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated IncA PF04156.9 CDO74420.1 - 0.007 15.9 0.0 0.007 15.9 0.0 1.9 2 0 0 2 2 2 1 IncA protein FlxA PF14282.1 CDO74420.1 - 0.013 15.4 0.3 0.013 15.4 0.2 1.9 2 0 0 2 2 2 0 FlxA-like protein DUF4140 PF13600.1 CDO74420.1 - 0.1 13.0 4.1 4.9 7.6 2.8 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) RNA_pol_3_Rpc31 PF11705.3 CDO74420.1 - 0.15 12.0 0.1 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Atg14 PF10186.4 CDO74420.1 - 0.35 9.7 4.6 0.53 9.1 3.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MerR-DNA-bind PF09278.6 CDO74420.1 - 0.74 10.2 5.0 27 5.2 1.8 2.4 2 0 0 2 2 2 0 MerR, DNA binding Mid2 PF04478.7 CDO74421.1 - 4.8e-05 22.8 3.5 6.9e-05 22.2 1.0 2.3 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor gpUL132 PF11359.3 CDO74421.1 - 0.0015 17.9 0.2 0.0015 17.9 0.1 2.0 2 0 0 2 2 2 1 Glycoprotein UL132 TMEM154 PF15102.1 CDO74421.1 - 0.0083 15.8 0.0 0.0083 15.8 0.0 2.4 3 0 0 3 3 3 1 TMEM154 protein family Herpes_gE PF02480.11 CDO74421.1 - 0.01 14.1 0.2 0.017 13.4 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Orthoreo_P10 PF07204.6 CDO74421.1 - 0.017 14.8 0.2 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF1049 PF06305.6 CDO74421.1 - 0.025 14.0 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Shisa PF13908.1 CDO74422.1 - 0.2 11.7 3.7 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1192 PF06698.6 CDO74422.1 - 0.22 11.3 1.3 0.39 10.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) IncA PF04156.9 CDO74422.1 - 1.6 8.3 4.3 5.7 6.4 0.2 2.1 2 0 0 2 2 2 0 IncA protein SKG6 PF08693.5 CDO74422.1 - 5.3 6.4 7.9 15 4.9 5.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CBM_21 PF03370.8 CDO74423.1 - 2.1e-24 85.6 0.0 3.1e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 Putative phosphatase regulatory subunit Redoxin PF08534.5 CDO74427.1 - 0.0037 16.8 0.0 0.0075 15.8 0.0 1.5 1 0 0 1 1 1 1 Redoxin HMG_box_2 PF09011.5 CDO74427.1 - 0.01 16.1 0.5 0.03 14.7 0.2 1.8 2 0 0 2 2 2 0 HMG-box domain Peptidase_S41 PF03572.13 CDO74428.1 - 0.0064 15.9 0.0 0.015 14.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Pkinase PF00069.20 CDO74433.1 - 0.097 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain SAP PF02037.22 CDO74435.1 - 3.9e-08 32.6 0.7 9.5e-08 31.3 0.3 1.8 2 0 0 2 2 2 1 SAP domain Med7 PF05983.6 CDO74436.1 - 1.3e-21 77.0 0.1 1.6e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 MED7 protein DUF4124 PF13511.1 CDO74437.1 - 0.21 11.6 4.1 1.4 9.0 2.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4124) RRM_6 PF14259.1 CDO74438.1 - 2.4e-11 43.4 0.1 1.2e-06 28.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO74438.1 - 7e-09 35.1 0.3 0.001 18.6 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO74438.1 - 0.00011 21.9 0.1 0.037 13.8 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_trans_1_2 PF13524.1 CDO74438.1 - 0.65 10.3 3.9 0.45 10.8 0.2 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 XPG_N PF00752.12 CDO74439.1 - 5.4e-33 113.2 0.0 1e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CDO74439.1 - 4.3e-29 100.4 0.0 8.7e-29 99.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CDO74439.1 - 3.2e-07 30.4 0.1 7.7e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Na_H_Exchanger PF00999.16 CDO74442.1 - 1.1e-53 182.1 28.0 4.1e-53 180.2 19.4 1.7 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF21 PF01595.15 CDO74442.1 - 0.1 11.8 2.1 0.39 9.9 1.4 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF21 DUF883 PF05957.8 CDO74442.1 - 0.16 12.3 1.6 0.39 11.1 1.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) p450 PF00067.17 CDO74443.1 - 7.8e-46 156.5 0.1 3.5e-39 134.6 0.0 2.8 2 1 1 3 3 3 2 Cytochrome P450 DSPc PF00782.15 CDO74443.1 - 3.2e-17 62.3 0.0 5.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDO74443.1 - 0.0022 17.3 0.1 0.004 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 CDO74443.1 - 0.1 11.3 0.1 0.16 10.6 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PSD4 PF07631.6 CDO74444.1 - 0.034 14.5 0.2 0.14 12.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) CAML PF14963.1 CDO74445.1 - 0.074 12.4 0.2 0.16 11.2 0.1 1.6 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Pkinase PF00069.20 CDO74446.1 - 7.3e-07 28.5 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74446.1 - 0.0043 16.1 0.1 0.014 14.4 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Amidohydro_4 PF13147.1 CDO74447.1 - 1.3e-12 48.3 4.1 8.3e-12 45.7 0.0 3.0 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 CDO74447.1 - 3.7e-07 30.1 0.0 6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CDO74447.1 - 0.0031 16.7 0.0 0.0064 15.7 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Ank_2 PF12796.2 CDO74448.1 - 8.5e-06 26.0 0.0 3.5e-05 24.0 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDO74448.1 - 2.3e-05 23.9 0.0 6.3e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 CDO74448.1 - 0.00065 19.6 0.0 0.0031 17.6 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 CDO74448.1 - 0.0054 17.2 0.0 0.02 15.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Sybindin PF04099.7 CDO74450.1 - 1.2e-21 76.8 0.0 1.5e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family MFS_1 PF07690.11 CDO74451.1 - 1.1e-24 86.7 49.1 3.2e-16 58.9 16.4 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 CDO74451.1 - 1.5e-08 33.3 22.9 5.1e-08 31.5 15.9 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SNF2_N PF00176.18 CDO74452.1 - 2.2e-66 223.7 0.1 3.4e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDO74452.1 - 1.6e-14 53.5 0.0 4.5e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO74452.1 - 1.5e-07 31.4 0.0 3.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_3 PF12836.2 CDO74452.1 - 2.2e-05 24.2 0.0 6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DEAD PF00270.24 CDO74452.1 - 3.7e-05 23.2 0.0 0.00027 20.4 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase HHH_6 PF14579.1 CDO74452.1 - 0.056 13.4 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF3552 PF12072.3 CDO74452.1 - 0.069 12.3 5.2 0.03 13.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Mito_carr PF00153.22 CDO74453.1 - 3.9e-10 39.3 0.0 5e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial carrier protein DUF4243 PF14027.1 CDO74453.1 - 0.0094 15.4 0.1 0.012 15.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) zf-CCCH PF00642.19 CDO74455.1 - 6.2e-14 51.2 15.3 3.6e-07 29.6 1.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CDO74455.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO74455.1 - 0.029 13.9 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruB_C PF09142.6 CDO74455.1 - 0.089 12.4 0.1 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal CART PF06373.6 CDO74455.1 - 0.9 9.5 3.8 8.6 6.3 0.5 2.8 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) TPR_1 PF00515.23 CDO74456.1 - 1.4e-26 90.9 19.7 0.00034 20.1 0.0 6.7 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 CDO74456.1 - 4.7e-26 90.2 20.8 1.6e-09 37.2 3.7 5.3 4 1 1 5 5 5 4 TPR repeat TPR_8 PF13181.1 CDO74456.1 - 5.4e-23 78.9 12.3 0.00011 21.6 0.0 7.7 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 CDO74456.1 - 9e-20 68.9 24.2 0.00055 19.6 0.1 7.0 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 CDO74456.1 - 1.2e-15 56.5 17.4 0.0039 17.6 0.2 7.9 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 CDO74456.1 - 2.4e-15 56.2 25.3 3.6e-08 33.2 0.9 5.9 1 1 4 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 CDO74456.1 - 2.9e-14 53.2 21.4 1.4e-05 25.6 0.8 6.3 4 4 3 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CDO74456.1 - 5.7e-14 50.7 14.4 0.0019 17.8 0.1 7.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 CDO74456.1 - 1.2e-09 38.4 12.0 0.013 15.8 0.1 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 CDO74456.1 - 1.9e-09 36.9 5.8 0.0016 18.5 0.6 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 CDO74456.1 - 2.8e-05 23.8 14.8 6.1e-05 22.7 0.6 4.8 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 CDO74456.1 - 4.6e-05 22.6 10.4 0.041 12.9 3.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CDO74456.1 - 0.00023 21.2 18.6 0.0097 16.0 0.1 4.3 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CDO74456.1 - 0.00056 19.7 11.5 0.019 14.8 0.1 5.5 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDO74456.1 - 0.0014 18.9 19.6 0.56 10.7 0.2 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_20 PF14561.1 CDO74456.1 - 0.0078 16.3 0.5 3.9 7.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.5 CDO74456.1 - 0.0081 14.9 0.2 0.03 13.0 0.0 2.0 2 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) FAT PF02259.18 CDO74456.1 - 0.018 14.0 5.2 0.025 13.5 0.7 2.7 2 2 0 2 2 2 0 FAT domain TPR_4 PF07721.9 CDO74456.1 - 0.03 14.7 6.6 0.54 10.8 0.0 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.13 CDO74456.1 - 0.041 13.7 0.1 0.041 13.7 0.1 3.0 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 CDO74456.1 - 0.6 9.4 8.3 2.9 7.2 0.1 3.6 1 1 1 2 2 2 0 26S proteasome subunit RPN7 GLTSCR1 PF15249.1 CDO74457.1 - 2e-19 69.7 1.2 2e-19 69.7 0.8 1.6 2 0 0 2 2 2 1 Glioma tumor suppressor candidate region F-box PF00646.28 CDO74458.1 - 0.00061 19.3 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO74458.1 - 0.013 15.1 0.1 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like Fungal_trans PF04082.13 CDO74459.1 - 3.8e-21 75.1 0.0 6.1e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 CDO74459.1 - 0.22 11.5 1.4 0.36 10.8 0.1 2.0 2 0 0 2 2 2 0 Gal4-like dimerisation domain DUF1674 PF07896.7 CDO74460.1 - 4.3e-10 39.6 2.2 1.1e-09 38.2 1.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Metal_resist PF13801.1 CDO74460.1 - 0.083 12.8 0.2 0.083 12.8 0.1 1.6 2 0 0 2 2 2 0 Heavy-metal resistance Hemerythrin PF01814.18 CDO74461.1 - 2.4e-13 50.3 2.2 2.5e-13 50.3 1.2 1.2 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_RpbA PF10789.4 CDO74461.1 - 0.0074 16.1 0.1 0.0094 15.7 0.1 1.3 1 0 0 1 1 1 1 Phage RNA polymerase binding, RpbA PriCT_2 PF08707.6 CDO74461.1 - 0.03 14.2 0.0 0.054 13.3 0.0 1.5 1 1 0 1 1 1 0 Primase C terminal 2 (PriCT-2) Glyco_hyd_65N_2 PF14498.1 CDO74461.1 - 0.072 12.7 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain BAR PF03114.13 CDO74462.1 - 2.8e-49 167.7 0.3 3.4e-49 167.4 0.2 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 CDO74462.1 - 0.00028 20.3 1.3 0.0034 16.7 0.2 2.1 2 0 0 2 2 2 1 Arfaptin-like domain HOOK PF05622.7 CDO74462.1 - 0.038 11.8 0.1 0.061 11.1 0.1 1.3 1 0 0 1 1 1 0 HOOK protein Vps5 PF09325.5 CDO74462.1 - 0.076 12.2 1.4 0.58 9.3 1.0 2.0 1 1 0 1 1 1 0 Vps5 C terminal like DUF3584 PF12128.3 CDO74463.1 - 3 5.0 31.4 4.6 4.4 21.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) F-box-like PF12937.2 CDO74464.1 - 4.2e-07 29.5 0.0 1e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO74464.1 - 0.0048 16.5 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain EMP70 PF02990.11 CDO74465.1 - 5.2e-153 510.2 1.7 1.2e-118 396.9 0.0 2.1 1 1 1 2 2 2 2 Endomembrane protein 70 ABC2_membrane_3 PF12698.2 CDO74465.1 - 0.0032 16.5 0.9 0.0032 16.5 0.6 3.0 2 1 1 3 3 3 1 ABC-2 family transporter protein tRNA-synt_1b PF00579.20 CDO74466.1 - 1.5e-59 201.5 0.0 1.9e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 CDO74466.1 - 0.00025 20.4 0.0 0.00059 19.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain TGT PF01702.13 CDO74467.1 - 1.9e-29 102.6 0.0 2.5e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DEAD PF00270.24 CDO74468.1 - 1.2e-38 132.2 0.0 2.1e-37 128.2 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO74468.1 - 7e-23 80.2 0.5 3.3e-22 78.1 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CDO74468.1 - 1e-21 76.5 5.4 3.9e-21 74.6 3.7 2.1 1 0 0 1 1 1 1 DBP10CT (NUC160) domain MFS_1 PF07690.11 CDO74469.1 - 6.9e-31 107.2 32.6 6.9e-31 107.2 22.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pap_E4 PF02711.9 CDO74470.1 - 0.6 10.9 4.8 3.4 8.5 0.8 2.7 2 1 0 2 2 2 0 E4 protein DDE_Tnp_4 PF13359.1 CDO74471.1 - 1e-22 80.3 0.0 1.3e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CDO74471.1 - 0.0035 16.7 0.1 0.0059 16.0 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO74471.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.16 CDO74471.1 - 0.024 14.1 0.2 0.089 12.3 0.1 1.8 1 1 0 1 1 1 0 Transposase DDE domain ABC_membrane PF00664.18 CDO74472.1 - 1.3e-66 224.8 26.5 3e-36 125.2 3.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CDO74472.1 - 1.8e-53 180.5 0.0 2.5e-31 108.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CDO74472.1 - 1.1e-09 38.6 0.0 0.0016 18.4 0.0 4.1 4 1 0 4 4 3 2 AAA domain SMC_N PF02463.14 CDO74472.1 - 3.2e-09 36.3 2.4 0.0076 15.5 0.0 3.6 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CDO74472.1 - 1.5e-07 30.8 0.6 0.015 14.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CDO74472.1 - 1.8e-06 27.5 0.1 0.006 16.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CDO74472.1 - 1e-05 25.4 0.1 0.083 12.8 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.1 CDO74472.1 - 2.1e-05 24.9 3.8 0.066 13.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 CDO74472.1 - 0.00018 21.5 0.5 0.36 10.7 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain Miro PF08477.8 CDO74472.1 - 0.00036 21.0 0.1 1.8 9.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 CDO74472.1 - 0.00046 19.4 2.4 0.15 11.2 0.1 2.6 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CDO74472.1 - 0.0028 17.8 0.3 2 8.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 CDO74472.1 - 0.0028 17.1 0.3 0.43 9.9 0.1 2.6 2 1 0 2 2 2 1 AAA-like domain ATP-synt_ab PF00006.20 CDO74472.1 - 0.0048 16.4 0.0 6.1 6.2 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 CDO74472.1 - 0.0061 17.3 5.1 0.31 11.8 0.2 3.5 3 1 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 CDO74472.1 - 0.008 15.7 1.0 9.4 5.6 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 CDO74472.1 - 0.0094 15.0 1.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 CDO74472.1 - 0.014 14.8 0.6 9.3 5.6 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_30 PF13604.1 CDO74472.1 - 0.019 14.5 1.2 1.6 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 CDO74472.1 - 0.022 13.4 0.5 2.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 CDO74472.1 - 0.033 13.8 0.5 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CDO74472.1 - 0.078 12.6 0.1 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase NACHT PF05729.7 CDO74472.1 - 0.1 12.2 0.3 0.8 9.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 CDO74472.1 - 0.13 12.1 2.6 5.4 6.8 0.1 2.8 3 0 0 3 3 3 0 Dynamin family AAA_33 PF13671.1 CDO74472.1 - 0.16 11.8 0.1 3.1 7.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 CDO74472.1 - 0.18 12.0 0.0 51 4.0 0.0 3.1 3 0 0 3 3 3 0 RNA helicase ABC_ATPase PF09818.4 CDO74472.1 - 0.2 10.1 0.3 4.1 5.8 0.0 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF87 PF01935.12 CDO74472.1 - 0.21 11.3 4.3 0.36 10.6 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 cobW PF02492.14 CDO74472.1 - 0.53 9.6 3.9 0.82 9.0 0.0 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CDO74472.1 - 0.56 10.5 4.3 16 5.8 0.2 3.6 3 0 0 3 3 3 0 AAA domain AhpC-TSA_2 PF13911.1 CDO74473.1 - 2.2e-14 53.3 0.0 3.9e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 CDO74473.1 - 1.2e-07 31.4 0.0 2.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CDO74473.1 - 2.2e-06 27.3 0.0 4.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Aa_trans PF01490.13 CDO74474.1 - 1.2e-82 277.6 34.1 1.4e-82 277.4 23.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_3 PF07859.8 CDO74475.1 - 1.3e-20 73.8 0.0 1.9e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CDO74475.1 - 7.2e-09 34.7 0.0 1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CDO74475.1 - 4.9e-05 23.1 0.0 6.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CDO74475.1 - 0.076 11.7 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family eIF-1a PF01176.14 CDO74476.1 - 8.8e-29 98.7 0.2 1.3e-28 98.1 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Metallophos PF00149.23 CDO74477.1 - 3.4e-35 121.2 0.3 4.2e-35 120.9 0.2 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VTC PF09359.5 CDO74478.1 - 3e-91 305.3 0.2 6.9e-91 304.1 0.0 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 CDO74478.1 - 4.2e-31 108.7 9.3 5.8e-24 85.3 3.5 2.2 1 1 1 2 2 2 2 SPX domain Gtr1_RagA PF04670.7 CDO74479.1 - 3.3e-34 118.0 1.0 3.7e-34 117.8 0.7 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Abhydrolase_3 PF07859.8 CDO74480.1 - 2.6e-17 63.1 0.0 3.9e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO74480.1 - 7.5e-08 32.2 0.1 9.2e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 CDO74480.1 - 4.4e-05 22.2 0.0 5.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Thioesterase PF00975.15 CDO74480.1 - 0.091 12.9 0.4 0.16 12.1 0.3 1.4 1 1 0 1 1 1 0 Thioesterase domain Ank_2 PF12796.2 CDO74483.1 - 1.7e-06 28.2 0.0 9.7e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDO74483.1 - 9.1e-06 26.0 0.0 0.0035 17.8 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CDO74483.1 - 0.00034 20.2 0.0 1.1 9.1 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CDO74483.1 - 0.0045 17.1 0.0 4.6 7.6 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO74483.1 - 0.028 14.6 0.0 7.5 7.1 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat PKD_channel PF08016.7 CDO74484.1 - 3.2e-06 25.8 17.3 1.9e-05 23.2 0.7 2.2 2 0 0 2 2 2 2 Polycystin cation channel Pkinase PF00069.20 CDO74485.1 - 3.9e-47 160.5 0.0 4.7e-29 101.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74485.1 - 5.9e-25 87.8 0.0 5.9e-22 77.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO74485.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Macro PF01661.16 CDO74486.1 - 1e-36 125.3 0.2 1.4e-36 124.9 0.2 1.2 1 0 0 1 1 1 1 Macro domain DUF1995 PF09353.5 CDO74486.1 - 0.078 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) Sugar_tr PF00083.19 CDO74487.1 - 3.2e-100 335.8 22.9 3.9e-100 335.5 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO74487.1 - 1.5e-26 92.9 56.6 1.6e-21 76.4 21.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CDO74487.1 - 0.0027 15.9 1.1 0.0027 15.9 0.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GDYXXLXY PF14345.1 CDO74487.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 GDYXXLXY protein WD40 PF00400.27 CDO74488.1 - 0.00019 21.1 0.0 0.098 12.5 0.0 3.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Epimerase PF01370.16 CDO74489.1 - 3.9e-09 36.3 0.1 0.00011 21.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO74489.1 - 1.5e-07 31.5 0.2 2.9e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 CDO74489.1 - 1.8e-07 30.6 0.0 3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 CDO74489.1 - 1.3e-05 24.2 0.6 3.6e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Shikimate_DH PF01488.15 CDO74489.1 - 5.9e-05 23.1 0.0 0.00037 20.5 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 CDO74489.1 - 0.00012 22.3 0.0 0.00022 21.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CDO74489.1 - 0.00014 21.0 0.1 0.00018 20.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 CDO74489.1 - 0.00051 20.0 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 CDO74489.1 - 0.00092 17.9 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 CDO74489.1 - 0.0033 17.8 0.0 0.008 16.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 CDO74489.1 - 0.004 16.1 0.0 0.0064 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CDO74489.1 - 0.0049 16.7 0.5 0.033 14.1 0.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 CDO74490.1 - 1.8e-07 30.6 0.0 2.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CDO74490.1 - 1.1e-06 28.7 0.1 1.7e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CDO74490.1 - 3.3e-06 26.2 0.0 6.4e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.15 CDO74490.1 - 0.0004 20.4 0.0 0.00063 19.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 CDO74490.1 - 0.00058 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CDO74490.1 - 0.0018 17.3 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 CDO74490.1 - 0.0041 17.0 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 CDO74490.1 - 0.0054 16.2 0.0 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CDO74490.1 - 0.013 15.4 0.1 0.052 13.4 0.1 1.8 1 1 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.12 CDO74490.1 - 0.015 15.6 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 CDO74490.1 - 0.05 12.3 0.0 0.069 11.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.11 CDO74490.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Epimerase PF01370.16 CDO74491.1 - 1.1e-10 41.3 0.1 3.4e-10 39.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO74491.1 - 4.1e-09 36.7 0.7 1.1e-08 35.3 0.5 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CDO74491.1 - 1.1e-08 34.1 0.0 1.8e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CDO74491.1 - 1.1e-07 31.3 0.2 1.6e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 CDO74491.1 - 2.5e-06 26.6 0.8 5.8e-05 22.1 0.0 2.5 1 1 0 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 CDO74491.1 - 1.6e-05 24.1 0.1 2.3e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 CDO74491.1 - 0.00021 21.6 0.1 0.0004 20.6 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CDO74491.1 - 0.0086 15.9 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 CDO74491.1 - 0.0087 14.9 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.11 CDO74491.1 - 0.012 16.1 0.1 0.021 15.3 0.1 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase F420_oxidored PF03807.12 CDO74491.1 - 0.014 15.7 0.3 0.14 12.6 0.2 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.11 CDO74491.1 - 0.015 15.6 0.4 0.035 14.5 0.1 1.7 2 0 0 2 2 1 0 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CDO74491.1 - 0.061 13.4 0.1 0.099 12.7 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 CDO74491.1 - 0.067 13.0 0.2 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CDO74492.1 - 4.7e-06 25.5 0.0 1.5e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CDO74492.1 - 8.1e-06 25.9 0.1 1.2e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CDO74492.1 - 2.2e-05 23.5 0.0 0.00086 18.2 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.8 CDO74492.1 - 5.3e-05 22.5 0.1 0.00026 20.3 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 CDO74492.1 - 7e-05 23.1 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 CDO74492.1 - 8e-05 22.1 0.1 0.0026 17.2 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CDO74492.1 - 0.00069 19.7 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CDO74492.1 - 0.005 17.2 0.1 0.014 15.7 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 CDO74492.1 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 CDO74493.1 - 2e-10 40.5 0.0 6.4e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO74493.1 - 1.9e-09 36.6 0.0 5.8e-09 35.0 0.1 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CDO74493.1 - 1.1e-08 34.6 0.2 1.8e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CDO74493.1 - 3.8e-08 33.5 0.0 9.5e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 CDO74493.1 - 2e-05 23.6 0.2 6.3e-05 22.0 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 CDO74493.1 - 4.1e-05 22.7 0.1 5.7e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 CDO74493.1 - 0.0012 17.7 0.1 0.0019 17.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 CDO74493.1 - 0.0017 18.7 0.1 0.0042 17.4 0.1 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 CDO74493.1 - 0.0034 17.6 0.0 0.0059 16.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CDO74493.1 - 0.025 14.4 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 CDO74493.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 KR domain Ldh_1_N PF00056.18 CDO74493.1 - 0.035 13.9 0.2 0.061 13.1 0.2 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.20 CDO74493.1 - 0.074 12.9 1.5 0.28 11.0 1.1 1.9 1 1 0 1 1 1 0 short chain dehydrogenase DXP_reductoisom PF02670.11 CDO74493.1 - 0.13 12.8 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.14 CDO74494.1 - 6.9e-10 38.0 0.0 2.5e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CDO74494.1 - 8.8e-09 34.9 0.1 1.5e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CDO74494.1 - 3.4e-08 33.2 0.1 2e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO74494.1 - 5.9e-08 32.9 0.1 1e-07 32.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CDO74494.1 - 4.1e-05 22.6 0.1 0.00016 20.6 0.0 1.9 1 1 1 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 CDO74494.1 - 0.00011 21.2 0.1 0.00016 20.7 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 CDO74494.1 - 0.00067 19.9 0.1 0.0016 18.7 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 CDO74494.1 - 0.0021 17.0 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 CDO74494.1 - 0.0033 17.8 0.1 0.01 16.2 0.1 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 CDO74494.1 - 0.005 16.5 0.1 0.0094 15.6 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CDO74494.1 - 0.014 15.3 1.6 0.074 12.9 1.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 CDO74494.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 CDO74494.1 - 0.043 13.6 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 CDO74494.1 - 0.12 12.9 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA PF01408.17 CDO74496.1 - 8.5e-25 87.6 0.0 1.5e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 CDO74496.1 - 0.049 13.9 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 CDO74497.1 - 3.3e-19 69.2 0.0 1e-10 41.4 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CDO74497.1 - 3.5e-05 22.8 0.0 0.003 16.5 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 CDO74497.1 - 0.00055 19.9 0.9 0.0017 18.3 0.6 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CDO74497.1 - 0.0054 16.6 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 CDO74497.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NPR3 PF03666.8 CDO74498.1 - 2.4e-55 187.8 0.6 1.1e-54 185.7 0.0 2.2 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Glyco_trans_1_3 PF13528.1 CDO74499.1 - 1.3e-10 41.0 0.0 1.3e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 CDO74499.1 - 0.21 11.2 0.0 0.55 9.8 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain WD40 PF00400.27 CDO74500.1 - 4e-06 26.5 0.0 0.23 11.4 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ADH_N PF08240.7 CDO74501.1 - 8.4e-11 41.6 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO74501.1 - 2.6e-09 36.7 0.0 4.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO74501.1 - 3e-06 28.1 0.0 5.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CDO74502.1 - 3.5e-17 62.1 0.1 8.7e-17 60.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO74502.1 - 2.3e-09 36.9 0.0 4.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DSPc PF00782.15 CDO74503.1 - 5.8e-28 97.1 0.0 1.3e-21 76.5 0.0 3.3 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDO74503.1 - 0.0046 16.3 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CDO74503.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate ADH_N PF08240.7 CDO74504.1 - 1.3e-09 37.7 0.0 2.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO74504.1 - 6.8e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO74504.1 - 0.059 14.2 0.0 0.15 12.9 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO74505.1 - 1.8e-14 53.3 0.0 2.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO74505.1 - 8e-11 41.5 0.0 3.2e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO74505.1 - 0.00027 21.8 0.0 0.00045 21.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CDO74506.1 - 1.3e-11 44.1 0.0 2.3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO74506.1 - 1.4e-08 34.4 0.0 3.9e-08 33.0 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CDO74506.1 - 5.3e-07 30.5 0.0 7.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.6 CDO74506.1 - 0.071 12.6 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Cupin domain ADH_zinc_N PF00107.21 CDO74507.1 - 8.1e-27 93.3 0.0 5.2e-13 48.6 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO74507.1 - 1.7e-14 53.4 0.0 3.2e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CDO74507.1 - 1.2e-10 42.3 0.0 5e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 CDO74507.1 - 0.021 14.5 0.0 8.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain ADH_zinc_N PF00107.21 CDO74508.1 - 1.4e-15 57.0 0.0 2.5e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO74508.1 - 8.2e-09 35.1 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GalKase_gal_bdg PF10509.4 CDO74509.1 - 2.9e-19 68.0 0.0 5e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CDO74509.1 - 1.7e-13 50.4 1.8 4.5e-13 49.0 0.7 2.1 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CDO74509.1 - 0.068 13.3 0.1 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal ADH_N PF08240.7 CDO74510.1 - 2.3e-18 65.9 0.0 5.4e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO74510.1 - 2.2e-14 53.1 0.1 1.5e-13 50.4 0.0 2.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO74510.1 - 9.8e-07 29.7 0.0 6.6e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF4191 PF13829.1 CDO74511.1 - 0.64 9.1 2.8 14 4.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF1469 PF07332.6 CDO74511.1 - 0.78 9.4 4.0 1.9 8.2 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) HET PF06985.6 CDO74512.1 - 9.5e-20 71.1 1.5 2.2e-19 70.0 1.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 2OG-FeII_Oxy PF03171.15 CDO74512.1 - 5.9e-11 42.5 0.0 1.4e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CDO74512.1 - 3.1e-10 40.5 0.0 8.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ABC_tran PF00005.22 CDO74513.1 - 5.8e-33 114.0 0.0 5.5e-32 110.9 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 CDO74513.1 - 6.6e-31 107.7 10.5 8.6e-31 107.3 7.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CDO74513.1 - 1.9e-05 24.8 0.0 0.24 11.3 0.0 2.3 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CDO74513.1 - 0.00016 20.9 0.4 0.026 13.7 0.0 2.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 CDO74513.1 - 0.00067 19.8 0.0 0.0071 16.5 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDO74513.1 - 0.0019 18.3 0.0 0.0091 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDO74513.1 - 0.002 18.1 0.0 0.0057 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CDO74513.1 - 0.0058 16.1 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CDO74513.1 - 0.01 16.6 0.0 0.03 15.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CDO74513.1 - 0.015 15.1 0.0 0.062 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CDO74513.1 - 0.034 13.8 0.0 0.085 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 CDO74513.1 - 0.037 13.2 0.0 0.078 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 CDO74513.1 - 0.039 14.2 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CDO74513.1 - 0.04 13.8 0.0 0.46 10.3 0.0 2.4 1 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CDO74513.1 - 0.13 12.1 1.3 0.76 9.7 0.2 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SPOR PF05036.8 CDO74514.1 - 0.13 12.4 0.3 0.3 11.2 0.2 1.6 1 0 0 1 1 1 0 Sporulation related domain APG6 PF04111.7 CDO74514.1 - 0.15 11.0 4.1 0.22 10.5 2.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Nif11 PF07862.6 CDO74514.1 - 0.17 11.8 1.0 0.42 10.5 0.4 1.9 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function GAS PF13851.1 CDO74514.1 - 0.41 9.8 7.0 0.25 10.5 3.5 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 CDO74514.1 - 0.44 10.4 12.4 0.15 11.9 6.7 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Bap31 PF05529.7 CDO74514.1 - 0.82 9.0 3.7 1.4 8.3 2.6 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DDRGK PF09756.4 CDO74514.1 - 1.6 8.0 10.8 2.3 7.5 7.5 1.2 1 0 0 1 1 1 0 DDRGK domain IncA PF04156.9 CDO74514.1 - 1.8 8.1 7.5 1.9 8.0 3.1 1.9 2 0 0 2 2 2 0 IncA protein DUF4337 PF14235.1 CDO74514.1 - 5 6.9 6.2 1.4 8.6 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Helicase_C PF00271.26 CDO74518.1 - 9.3e-12 44.6 0.0 2.5e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UBN2_2 PF14227.1 CDO74518.1 - 2.8e-11 43.0 0.4 1.3e-10 40.8 0.0 2.3 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO74518.1 - 4.9e-07 29.5 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_6 PF15288.1 CDO74518.1 - 0.00012 21.6 1.0 0.00055 19.5 0.7 2.2 1 0 0 1 1 1 1 Zinc knuckle DEAD PF00270.24 CDO74518.1 - 0.00019 20.9 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC PF00098.18 CDO74518.1 - 0.47 10.4 4.2 0.81 9.7 0.3 2.7 2 0 0 2 2 2 0 Zinc knuckle UBN2_2 PF14227.1 CDO74519.1 - 8.3e-17 60.8 0.0 4e-16 58.6 0.0 2.1 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO74519.1 - 8e-12 44.9 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type BRF1 PF07741.8 CDO74519.1 - 2.7 8.2 4.9 10 6.4 0.6 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain MRI PF15325.1 CDO74520.1 - 0.17 12.8 1.7 0.27 12.2 1.2 1.4 1 1 0 1 1 1 0 Modulator of retrovirus infection DUF659 PF04937.10 CDO74521.1 - 1.6e-09 37.4 0.0 3.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ADIP PF11559.3 CDO74522.1 - 0.062 13.1 2.5 0.13 12.1 1.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.3 CDO74522.1 - 0.092 12.0 3.4 0.12 11.6 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) bZIP_2 PF07716.10 CDO74522.1 - 0.22 11.3 8.7 0.09 12.6 2.5 2.4 1 1 1 2 2 2 0 Basic region leucine zipper DDE_Tnp_4 PF13359.1 CDO74523.1 - 5.6e-15 55.2 0.0 8.4e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease MANEC PF07502.9 CDO74524.1 - 0.017 15.1 0.9 0.039 13.9 0.6 1.5 1 0 0 1 1 1 0 MANEC domain Asp_protease_2 PF13650.1 CDO74526.1 - 0.0032 17.9 0.0 0.0058 17.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CDO74526.1 - 0.053 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.22 CDO74528.1 - 3.2e-24 85.4 0.0 5.5e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO74528.1 - 1.3e-20 73.7 0.0 4.3e-19 68.7 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.12 CDO74528.1 - 6.3e-12 45.4 0.2 4e-11 42.8 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.19 CDO74528.1 - 9.2e-07 28.4 0.1 2e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CDO74528.1 - 0.00085 18.6 0.1 0.002 17.4 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger zf-CCHC PF00098.18 CDO74528.1 - 0.031 14.1 0.3 0.073 13.0 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle UBN2 PF14223.1 CDO74528.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Transposase_21 PF02992.9 CDO74531.1 - 0.00019 20.6 0.1 0.00031 19.9 0.0 1.3 2 0 0 2 2 2 1 Transposase family tnp2 RVT_1 PF00078.22 CDO74534.1 - 1.6e-10 40.7 0.1 1.9e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pho88 PF10032.4 CDO74535.1 - 4.9e-74 247.7 0.8 5.4e-74 247.5 0.5 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF368 PF04018.8 CDO74535.1 - 0.081 12.1 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF368) SNARE_assoc PF09335.6 CDO74538.1 - 1.4e-14 54.3 8.9 2.6e-14 53.4 5.2 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1772 PF08592.6 CDO74538.1 - 0.045 13.4 3.6 0.1 12.3 2.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) SNARE_assoc PF09335.6 CDO74539.1 - 9.4e-14 51.6 4.1 9.4e-14 51.6 2.8 2.1 1 1 0 2 2 2 1 SNARE associated Golgi protein DUF2910 PF11139.3 CDO74539.1 - 0.072 12.2 8.1 0.087 11.9 1.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2910) 2TM PF13239.1 CDO74539.1 - 7.3 6.7 9.9 4.6 7.3 1.2 3.0 2 2 1 3 3 3 0 2TM domain SNARE_assoc PF09335.6 CDO74540.1 - 2.2e-12 47.2 6.5 2.2e-12 47.2 4.5 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein Sigma_reg_N PF13800.1 CDO74540.1 - 0.67 10.0 3.8 20 5.2 0.4 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal SNARE_assoc PF09335.6 CDO74541.1 - 2e-14 53.8 7.3 2e-14 53.8 5.0 2.2 2 1 1 3 3 3 1 SNARE associated Golgi protein LrgA PF03788.9 CDO74541.1 - 0.015 14.9 3.5 0.015 14.9 2.4 2.1 3 0 0 3 3 3 0 LrgA family DUF3753 PF12575.3 CDO74541.1 - 3.7 7.4 5.7 2.1 8.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) PH PF00169.24 CDO74542.1 - 5.1e-05 23.4 0.0 9.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 PH domain Nucleoplasmin PF03066.10 CDO74542.1 - 5 6.6 7.8 9.3 5.7 5.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin RVT_2 PF07727.9 CDO74544.1 - 1.5e-82 276.2 0.0 2e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF659 PF04937.10 CDO74545.1 - 0.00035 20.0 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) ARPC4 PF05856.7 CDO74545.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) MRP-S25 PF13741.1 CDO74545.1 - 0.069 12.6 0.1 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 DUF3596 PF12167.3 CDO74545.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) DUF962 PF06127.6 CDO74546.1 - 6.4e-23 80.4 4.4 9.5e-23 79.9 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Bac_rhodopsin PF01036.13 CDO74546.1 - 0.11 11.7 3.3 0.17 11.1 2.3 1.4 1 1 0 1 1 1 0 Bacteriorhodopsin-like protein adh_short_C2 PF13561.1 CDO74547.1 - 2.5e-21 76.5 0.0 1.2e-19 71.1 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO74547.1 - 2.7e-21 76.2 1.5 7.9e-21 74.6 1.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO74547.1 - 1.3e-07 31.4 0.2 2.1e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CDO74547.1 - 0.00017 21.3 1.3 0.00018 21.2 0.2 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 CDO74547.1 - 0.0091 15.7 0.4 0.024 14.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.17 CDO74548.1 - 1.7e-71 241.1 0.0 2e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 CDO74549.1 - 4.2e-29 100.7 2.9 4.2e-29 100.7 2.0 2.1 3 0 0 3 3 3 1 FAD binding domain MS_channel PF00924.13 CDO74550.1 - 1.2e-20 73.7 0.2 1.9e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CDO74550.1 - 6.2e-05 22.0 0.0 0.00013 20.9 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CDO74550.1 - 0.00015 21.3 0.1 0.00048 19.7 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CDO74550.1 - 0.00024 20.2 0.1 0.00052 19.2 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CDO74550.1 - 0.00096 19.2 0.2 0.0025 17.8 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair Hemagglutinin PF00509.13 CDO74551.1 - 0.07 11.2 2.6 0.083 11.0 1.8 1.2 1 0 0 1 1 1 0 Haemagglutinin Sec8_exocyst PF04048.9 CDO74551.1 - 0.52 9.9 14.0 0.71 9.4 9.7 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain APG6 PF04111.7 CDO74551.1 - 0.78 8.7 19.0 1 8.3 13.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TROVE PF05731.6 CDO74551.1 - 0.93 8.1 12.6 1.1 7.8 8.7 1.1 1 0 0 1 1 1 0 TROVE domain GBP_C PF02841.9 CDO74551.1 - 1.2 8.2 21.7 1.5 7.9 15.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Cluap1 PF10234.4 CDO74551.1 - 5.3 6.1 21.8 1.1 8.4 4.2 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 Birna_RdRp PF04197.7 CDO74551.1 - 8 4.3 14.0 9.5 4.1 9.7 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) LMBR1 PF04791.11 CDO74551.1 - 8.5 4.8 12.7 9.8 4.6 8.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PDT PF00800.13 CDO74552.1 - 0.16 11.4 4.7 0.2 11.1 3.3 1.2 1 0 0 1 1 1 0 Prephenate dehydratase Herpes_UL17 PF04559.7 CDO74552.1 - 0.27 9.7 6.5 0.32 9.5 4.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL17 protein HutP PF09021.6 CDO74552.1 - 1.5 9.0 7.1 2.1 8.5 4.9 1.2 1 0 0 1 1 1 0 HutP APG6 PF04111.7 CDO74552.1 - 2.5 7.0 19.9 3 6.8 13.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 TMPIT PF07851.8 CDO74552.1 - 2.8 6.9 11.8 3.5 6.6 8.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein DSPc PF00782.15 CDO74552.1 - 4.7 6.7 7.1 1.1 8.7 1.7 1.9 1 1 1 2 2 2 0 Dual specificity phosphatase, catalytic domain VirC2 PF07181.6 CDO74552.1 - 7.1 5.9 7.6 0.51 9.7 0.7 2.0 1 1 1 2 2 2 0 VirC2 protein F-box-like PF12937.2 CDO74555.1 - 7.3e-08 32.0 0.3 0.001 18.7 0.1 2.6 2 0 0 2 2 2 2 F-box-like LRR_8 PF13855.1 CDO74555.1 - 0.035 13.8 0.0 22 4.8 0.0 3.9 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 CDO74555.1 - 5.7 6.6 7.0 26 4.5 0.1 4.3 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) DUF2838 PF10998.3 CDO74556.1 - 2.2e-38 130.5 10.2 2.2e-38 130.5 7.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) NifU_N PF01592.11 CDO74557.1 - 7.8e-52 174.5 0.2 1.8e-51 173.3 0.0 1.6 2 0 0 2 2 2 1 NifU-like N terminal domain Nop PF01798.13 CDO74558.1 - 1.6e-44 150.7 0.4 3e-44 149.9 0.3 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 CDO74558.1 - 2.1e-34 118.5 1.4 2.1e-34 118.5 1.0 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain NOSIC PF08060.8 CDO74558.1 - 7.6e-18 64.0 0.1 1.6e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain Helicase_C PF00271.26 CDO74559.1 - 5.2e-13 48.6 0.0 1.6e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO74559.1 - 1.1e-05 24.9 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC_6 PF15288.1 CDO74559.1 - 2.7e-05 23.7 1.0 6.1e-05 22.5 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle AhpC-TSA_2 PF13911.1 CDO74559.1 - 0.0017 18.2 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AAA_14 PF13173.1 CDO74559.1 - 0.038 13.8 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3295 PF11702.3 CDO74560.1 - 0.073 12.0 0.8 0.25 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) DUF111 PF01969.12 CDO74560.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF111 Peptidase_M20 PF01546.23 CDO74561.1 - 2.3e-23 82.6 0.0 3.9e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CDO74561.1 - 1.1e-08 34.7 0.0 3.9e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF659 PF04937.10 CDO74562.1 - 0.00013 21.4 0.0 0.00035 20.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) CTP_transf_1 PF01148.15 CDO74563.1 - 2.5e-08 33.9 9.4 6.2e-07 29.3 7.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase family Pkinase PF00069.20 CDO74564.1 - 1.3e-09 37.6 0.0 1.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74564.1 - 3.3e-05 23.0 0.0 5.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 CDO74565.1 - 1.4e-23 83.2 46.1 2.1e-23 82.6 31.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO74565.1 - 7.3e-09 34.6 7.8 7.3e-09 34.6 5.4 3.4 2 1 2 4 4 4 1 Sugar (and other) transporter CRAL_TRIO PF00650.15 CDO74566.1 - 2.4e-26 92.1 0.0 4.1e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CDO74566.1 - 2.3e-08 34.0 0.1 7.7e-08 32.3 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CDO74566.1 - 0.0013 18.6 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Hpt PF01627.18 CDO74567.1 - 3.1e-09 36.7 0.1 4.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Hpt domain MIP-T3 PF10243.4 CDO74567.1 - 2.1 6.7 6.0 2.6 6.4 4.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 CDO74567.1 - 5.6 6.2 14.4 6.6 6.0 10.0 1.1 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 CDO74568.1 - 5.9e-28 95.7 13.6 1.9e-09 37.0 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 CDO74568.1 - 4.1e-20 72.0 0.0 7.3e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CDO74568.1 - 8.6e-16 57.6 0.0 1.4e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.3 CDO74568.1 - 0.00033 18.9 0.8 0.077 11.1 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CDO74568.1 - 0.00049 20.2 0.2 1.2 9.5 0.0 3.7 3 0 0 3 3 3 2 PQQ-like domain Nucleoporin_N PF08801.6 CDO74568.1 - 0.013 14.2 0.6 0.54 8.9 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like zf-RING_2 PF13639.1 CDO74569.1 - 7.7e-11 41.6 1.3 1.4e-10 40.7 0.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDO74569.1 - 4.2e-06 26.7 0.8 8.6e-06 25.7 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CDO74569.1 - 8.8e-06 25.6 0.4 1.6e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO74569.1 - 2.6e-05 23.7 0.2 4.6e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO74569.1 - 0.00014 21.5 0.2 0.00024 20.7 0.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CDO74569.1 - 0.0061 16.2 1.9 0.011 15.4 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDO74569.1 - 0.024 14.3 0.1 0.053 13.2 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 CDO74569.1 - 0.024 14.4 0.3 0.046 13.5 0.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Nitroreductase PF00881.19 CDO74569.1 - 0.052 13.3 0.5 0.14 11.9 0.3 1.7 1 0 0 1 1 1 0 Nitroreductase family RINGv PF12906.2 CDO74569.1 - 0.091 12.8 0.5 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 CDO74569.1 - 0.1 12.5 1.9 0.18 11.7 1.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Methyltransf_32 PF13679.1 CDO74570.1 - 7.9e-20 70.9 0.2 9.4e-19 67.4 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO74570.1 - 0.0002 21.9 0.0 0.00058 20.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO74570.1 - 0.018 15.4 0.0 0.056 13.9 0.0 1.9 1 1 0 2 2 2 0 Methyltransferase domain TRM13 PF05206.9 CDO74570.1 - 0.023 13.9 0.0 0.42 9.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase TRM13 ATP12 PF07542.6 CDO74570.1 - 0.048 13.6 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 ATP12 chaperone protein Methyltransf_11 PF08241.7 CDO74570.1 - 0.13 12.7 0.1 0.34 11.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain HVSL PF09749.4 CDO74571.1 - 6.7e-39 133.3 0.0 4e-38 130.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 CDO74571.1 - 7.8e-06 25.6 0.3 1.8e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily RRM_6 PF14259.1 CDO74572.1 - 4.5e-10 39.3 0.0 9.7e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO74572.1 - 2.1e-07 30.4 0.0 4.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO74572.1 - 2.3e-05 24.0 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CDO74572.1 - 6.7e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.1 CDO74572.1 - 0.0013 18.4 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF659 PF04937.10 CDO74573.1 - 8.9e-07 28.5 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.9 CDO74573.1 - 1.7e-05 24.3 0.0 3.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF772 PF05598.6 CDO74573.1 - 0.036 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Transposase domain (DUF772) TetR_C_7 PF14246.1 CDO74573.1 - 0.051 13.7 0.1 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal region Sec62 PF03839.11 CDO74576.1 - 2.7e-46 157.7 4.3 2.3e-45 154.7 1.5 2.0 2 0 0 2 2 2 2 Translocation protein Sec62 TPR_12 PF13424.1 CDO74577.1 - 7.1e-08 32.2 11.9 0.038 13.9 0.1 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 CDO74577.1 - 9.3e-06 25.2 3.9 1.9 8.2 0.0 4.3 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 CDO74577.1 - 0.00013 21.6 11.3 0.031 14.1 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO74577.1 - 0.0012 18.4 3.9 0.37 10.6 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDO74577.1 - 0.0035 16.8 8.7 0.027 14.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDO74577.1 - 0.0075 16.8 15.5 1.1 10.0 0.8 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO74577.1 - 0.0088 15.7 0.9 0.71 9.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDO74577.1 - 0.02 15.0 0.2 0.42 10.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CDO74577.1 - 0.029 15.0 13.6 5.2 7.8 1.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 CDO74577.1 - 0.07 13.0 2.4 12 5.8 0.0 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Moricin PF06451.6 CDO74577.1 - 0.21 11.1 0.6 0.49 9.9 0.0 1.9 2 0 0 2 2 2 0 Moricin TPR_6 PF13174.1 CDO74577.1 - 0.22 12.0 8.6 0.26 11.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.24 CDO74578.1 - 2.2e-41 141.1 0.5 3.8e-41 140.3 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO74578.1 - 1e-23 82.9 0.1 2.1e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO74578.1 - 0.0019 18.0 0.0 0.011 15.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CDO74578.1 - 0.042 12.9 0.1 0.11 11.5 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Metallophos PF00149.23 CDO74579.1 - 1.2e-44 152.0 0.1 1.6e-44 151.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PH_9 PF15410.1 CDO74580.1 - 1e-10 41.7 0.2 2e-06 27.9 0.1 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.24 CDO74580.1 - 3.2e-05 24.0 0.0 0.0086 16.2 0.0 2.4 2 0 0 2 2 2 2 PH domain TRAP_alpha PF03896.11 CDO74580.1 - 2.9 6.8 4.3 6.4 5.6 3.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1769 PF08588.5 CDO74582.1 - 1e-14 54.2 0.0 2.2e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Stress-antifung PF01657.12 CDO74583.1 - 0.24 11.7 2.4 1.3 9.4 0.2 2.5 2 0 0 2 2 2 0 Salt stress response/antifungal DUF2076 PF09849.4 CDO74585.1 - 4.1e-05 23.7 10.2 5.3e-05 23.3 7.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CDO74585.1 - 0.0032 17.3 1.7 0.0063 16.3 1.2 1.5 1 1 0 1 1 1 1 CHCH domain zinc-ribbons_6 PF07191.7 CDO74585.1 - 0.075 12.8 3.2 0.11 12.3 2.2 1.2 1 0 0 1 1 1 0 zinc-ribbons DUF605 PF04652.11 CDO74585.1 - 2.8 7.2 10.8 3.2 7.0 7.5 1.1 1 0 0 1 1 1 0 Vta1 like EXS PF03124.9 CDO74587.1 - 1.2e-66 225.1 20.4 2.1e-65 221.0 14.1 2.0 1 1 0 1 1 1 1 EXS family SPX PF03105.14 CDO74587.1 - 7.3e-28 98.1 0.1 2.2e-27 96.5 0.1 1.7 1 1 0 1 1 1 1 SPX domain SEA PF01390.15 CDO74587.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 SEA domain Vps16_C PF04840.7 CDO74588.1 - 4.4e-86 288.7 0.4 6.2e-86 288.2 0.3 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 CDO74588.1 - 1.7e-80 270.6 0.0 2.4e-78 263.5 0.0 2.1 1 1 0 1 1 1 1 Vps16, N-terminal region DnaJ PF00226.26 CDO74590.1 - 8e-15 54.3 0.1 1.3e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain APH PF01636.18 CDO74591.1 - 1.1e-14 54.8 0.0 2.1e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 CDO74592.1 - 0.0021 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family MANEC PF07502.9 CDO74593.1 - 0.024 14.6 0.8 0.06 13.3 0.5 1.6 1 0 0 1 1 1 0 MANEC domain Apc1 PF12859.2 CDO74594.1 - 2.2 8.5 4.4 3.5 7.9 0.5 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 1 HTH_45 PF14947.1 CDO74595.1 - 0.15 11.8 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DUF1308 PF07000.6 CDO74596.1 - 1.1e-24 86.7 0.0 4.1e-24 84.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Aldedh PF00171.17 CDO74597.1 - 9.6e-121 403.3 0.0 1.1e-120 403.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SpaB_C PF14028.1 CDO74597.1 - 0.0062 16.1 1.2 0.022 14.3 0.3 1.9 2 0 0 2 2 2 1 SpaB C-terminal domain OmdA PF13376.1 CDO74597.1 - 0.045 13.4 0.2 0.085 12.5 0.1 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated tRNA-synt_2b PF00587.20 CDO74598.1 - 3.2e-35 121.2 0.0 5.7e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CDO74598.1 - 4.2e-19 68.5 7.5 4.2e-19 68.5 5.2 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.6 CDO74598.1 - 0.046 13.5 1.1 0.11 12.4 0.7 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF469 PF04320.9 CDO74598.1 - 0.09 13.5 2.4 0.16 12.7 0.3 2.5 3 1 1 4 4 4 0 Protein with unknown function (DUF469) eIF3_N PF09440.5 CDO74598.1 - 5.6 7.1 9.9 1 9.4 1.6 3.1 3 1 1 4 4 4 0 eIF3 subunit 6 N terminal domain SET PF00856.23 CDO74599.1 - 1.3e-26 93.8 0.9 2e-25 89.9 0.0 2.9 3 0 0 3 3 3 1 SET domain N-SET PF11764.3 CDO74599.1 - 1.2e-11 44.7 3.4 1.2e-11 44.7 2.3 3.2 2 1 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.17 CDO74599.1 - 8.3e-09 34.9 0.0 9.1e-07 28.4 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO74599.1 - 5.6e-08 32.6 0.0 0.00014 21.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 CDO74599.1 - 0.00021 20.5 0.0 0.51 9.6 0.0 2.4 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated RRM_5 PF13893.1 CDO74599.1 - 0.01 15.6 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acp26Ab PF05777.7 CDO74599.1 - 0.098 13.1 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) Abhydrolase_6 PF12697.2 CDO74601.1 - 1.7e-09 37.9 0.2 2.4e-09 37.3 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO74601.1 - 0.00045 19.8 0.0 0.00051 19.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 CDO74601.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CDO74601.1 - 0.021 14.5 0.1 0.033 13.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 CDO74601.1 - 0.031 12.5 0.0 0.041 12.1 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II WD40 PF00400.27 CDO74604.1 - 3e-14 52.2 0.7 0.005 16.6 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat BUD22 PF09073.5 CDO74604.1 - 3.8 6.4 17.1 5.6 5.9 11.9 1.1 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.7 CDO74604.1 - 5.9 6.7 7.5 8.3 6.2 5.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 CDO74604.1 - 8.7 4.1 18.8 12 3.6 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family CVNH PF08881.5 CDO74605.1 - 0.0054 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 CVNH domain Fes1 PF08609.5 CDO74605.1 - 0.011 16.1 0.1 0.026 15.0 0.1 1.6 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 MoeZ_MoeB PF05237.8 CDO74605.1 - 0.074 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 MoeZ/MoeB domain Baculo_PEP_C PF04513.7 CDO74605.1 - 0.13 12.1 1.3 20 5.0 0.0 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Alpha-amylase PF00128.19 CDO74608.1 - 1.9e-22 80.0 1.0 5.6e-20 71.9 0.7 3.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 CDO74608.1 - 8.2e-15 54.9 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 CDO74608.1 - 2.6e-09 37.3 0.0 6.6e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CDO74608.1 - 3.6e-08 33.0 0.0 6.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase PF00069.20 CDO74609.1 - 5.3e-70 235.5 0.0 7.4e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74609.1 - 3.2e-48 164.0 0.0 5.3e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CDO74609.1 - 3.2e-15 55.9 0.0 6.9e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 CDO74609.1 - 1.4e-13 50.7 0.1 2.9e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CDO74609.1 - 6.5e-13 48.3 0.1 1.4e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 CDO74609.1 - 3.4e-06 26.2 0.0 0.00043 19.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CDO74609.1 - 0.026 14.2 0.1 0.29 10.8 0.1 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family Y1_Tnp PF01797.11 CDO74609.1 - 0.34 10.7 0.0 0.68 9.8 0.0 1.4 1 0 0 1 1 1 0 Transposase IS200 like TRM PF02005.11 CDO74610.1 - 4.6e-92 308.8 0.3 3.1e-61 207.4 0.1 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 CDO74610.1 - 0.039 13.5 0.0 0.086 12.4 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein PrmA PF06325.8 CDO74610.1 - 0.11 11.6 0.1 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ferric_reduct PF01794.14 CDO74611.1 - 8.8e-14 51.6 13.6 8.8e-14 51.6 9.4 2.4 2 0 0 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CDO74611.1 - 7.4e-13 48.2 0.0 2e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CDO74611.1 - 0.00015 21.6 0.1 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DDE_Tnp_4 PF13359.1 CDO74612.1 - 1e-22 80.3 0.0 1.3e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CDO74612.1 - 0.0035 16.7 0.1 0.0059 16.0 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO74612.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.16 CDO74612.1 - 0.024 14.1 0.2 0.089 12.3 0.1 1.8 1 1 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 CDO74613.1 - 2.1e-05 25.0 0.3 4.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CDO74613.1 - 0.00023 21.2 0.4 0.00062 19.8 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pap_E4 PF02711.9 CDO74613.1 - 2.2 9.1 5.2 4 8.3 0.7 2.7 2 1 0 2 2 2 0 E4 protein XPG_I PF00867.13 CDO74615.1 - 1.2e-19 70.1 0.0 1.9e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CDO74615.1 - 2.8e-05 24.2 0.0 6.4e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CDO74615.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing Spherulin4 PF12138.3 CDO74616.1 - 3.1e-44 151.3 0.0 3.5e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 UPRTase PF14681.1 CDO74617.1 - 6.7e-68 227.9 0.0 7.6e-68 227.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CDO74617.1 - 5.9e-06 26.0 0.0 8.3e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_1 PF00667.15 CDO74618.1 - 4.5e-36 124.3 0.0 3.4e-18 65.9 0.0 2.3 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.16 CDO74618.1 - 1e-08 35.6 0.0 2.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Glyco_hydro_9 PF00759.14 CDO74619.1 - 1.2e-90 304.5 9.2 1.7e-90 304.0 6.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 SKG6 PF08693.5 CDO74619.1 - 0.037 13.3 4.9 0.07 12.4 3.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GFO_IDH_MocA PF01408.17 CDO74620.1 - 3e-21 76.1 0.1 7.4e-21 74.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CDO74620.1 - 4.3e-05 23.2 0.0 8.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 CDO74620.1 - 0.00069 20.0 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CDO74620.1 - 0.0031 17.7 0.0 0.0053 17.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CDO74620.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AAA_33 PF13671.1 CDO74620.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.2 CDO74621.1 - 3.9e-10 39.2 0.4 9.3e-10 38.0 0.3 1.7 1 0 0 1 1 1 1 F-box-like Methyltransf_8 PF05148.10 CDO74622.1 - 1.2e-64 217.9 0.0 1.4e-63 214.4 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.1 CDO74622.1 - 0.00017 21.3 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO74622.1 - 0.0012 19.2 0.1 0.007 16.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO74622.1 - 0.021 14.4 0.6 0.3 10.6 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 CDO74622.1 - 0.083 13.3 0.2 0.31 11.5 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Ndc1_Nup PF09531.5 CDO74622.1 - 6.3 5.0 9.0 9 4.5 6.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AAA_10 PF12846.2 CDO74623.1 - 1.7e-07 30.9 0.1 9e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain Zot PF05707.7 CDO74623.1 - 0.00019 20.9 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF87 PF01935.12 CDO74623.1 - 0.00042 20.2 0.0 0.012 15.4 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 CDO74623.1 - 0.0019 18.3 0.0 0.037 14.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 CDO74623.1 - 0.01 15.3 0.1 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase JmjC PF02373.17 CDO74624.1 - 9.1e-15 54.8 0.0 2.2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase C1_1 PF00130.17 CDO74624.1 - 0.015 15.0 2.4 0.037 13.7 1.7 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_2 PF14445.1 CDO74624.1 - 0.77 9.7 12.4 0.062 13.2 2.6 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Response_reg PF00072.19 CDO74625.1 - 1.5e-23 82.9 0.0 8.4e-17 61.1 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain DUF3546 PF12066.3 CDO74626.1 - 2.4e-14 53.2 0.8 7.9e-14 51.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 CDO74626.1 - 4.6e-12 46.5 1.3 4.6e-12 46.5 0.9 2.8 3 0 0 3 3 3 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 CDO74626.1 - 3e-06 26.7 0.4 9e-06 25.1 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.2 CDO74626.1 - 0.041 13.9 1.9 0.75 9.9 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.17 CDO74626.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO74627.1 - 2.9e-07 30.3 0.0 1.1e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO74627.1 - 0.00054 19.5 0.0 0.8 9.3 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO74627.1 - 0.041 13.7 0.0 0.19 11.6 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_13 PF13166.1 CDO74628.1 - 0.0038 15.7 14.6 0.0045 15.5 10.1 1.0 1 0 0 1 1 1 1 AAA domain HAUS-augmin3 PF14932.1 CDO74628.1 - 0.032 13.4 17.5 0.039 13.1 12.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4551 PF15087.1 CDO74628.1 - 0.051 11.9 6.9 0.056 11.8 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) APG6 PF04111.7 CDO74628.1 - 0.086 11.8 21.0 0.11 11.5 14.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 TMPIT PF07851.8 CDO74628.1 - 0.091 11.8 11.3 0.12 11.4 7.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein GvpL_GvpF PF06386.6 CDO74628.1 - 0.15 11.6 9.8 0.18 11.3 6.8 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Fijivirus_P9-2 PF06837.6 CDO74628.1 - 0.19 10.8 0.9 0.27 10.3 0.3 1.5 1 1 0 1 1 1 0 Fijivirus P9-2 protein Orbi_VP5 PF00901.12 CDO74628.1 - 0.32 9.1 14.2 0.38 8.9 9.8 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 eIF-4B PF06273.6 CDO74628.1 - 0.38 9.4 8.6 0.45 9.2 6.0 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Baculo_PEP_C PF04513.7 CDO74628.1 - 0.63 9.8 4.1 0.94 9.3 1.6 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FNIP_N PF14636.1 CDO74628.1 - 0.68 10.4 4.4 0.85 10.1 3.1 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF2951 PF11166.3 CDO74628.1 - 0.95 9.3 11.7 5.2 7.0 5.7 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) VTC PF09359.5 CDO74628.1 - 1.3 8.0 10.5 3.9 6.4 7.3 1.7 1 1 0 1 1 1 0 VTC domain Acyl-CoA_ox_N PF14749.1 CDO74628.1 - 1.3 9.3 7.7 1.9 8.7 5.3 1.5 1 1 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Reo_sigmaC PF04582.7 CDO74628.1 - 1.5 7.9 4.0 2 7.4 2.8 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 CDO74628.1 - 2.8 6.7 17.4 3.5 6.4 12.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RP-C_C PF11800.3 CDO74628.1 - 3.3 7.3 9.9 4.1 7.0 6.9 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region PLRV_ORF5 PF01690.12 CDO74628.1 - 3.7 6.5 9.8 4.2 6.3 6.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein RuvC PF02075.12 CDO74628.1 - 3.7 7.3 7.7 2.2 8.0 3.3 2.0 1 1 1 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC Mgr1 PF08602.5 CDO74628.1 - 4.2 6.2 9.7 4.9 6.0 6.7 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit P16-Arc PF04699.9 CDO74628.1 - 5.9 6.8 13.8 3 7.8 7.3 1.8 1 1 1 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2894 PF11445.3 CDO74628.1 - 7 6.8 12.5 8.8 6.5 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DYW_deaminase PF14432.1 CDO74628.1 - 7.6 6.5 9.4 4.4 7.3 4.4 1.8 1 1 1 2 2 2 0 DYW family of nucleic acid deaminases dUTPase PF00692.14 CDO74630.1 - 4.4e-35 119.9 0.0 9.5e-33 112.4 0.0 2.1 2 0 0 2 2 2 2 dUTPase Peptidase_M43 PF05572.8 CDO74631.1 - 2.2e-15 56.5 0.0 4.1e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 CDO74631.1 - 1.3e-06 28.4 0.1 2e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CDO74631.1 - 9e-06 25.8 0.2 1.2e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CDO74631.1 - 8e-05 23.1 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 CDO74631.1 - 0.00071 18.9 0.5 0.0011 18.3 0.3 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 CDO74631.1 - 0.0036 16.8 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 CDO74631.1 - 0.028 14.1 0.3 0.053 13.2 0.2 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.4 CDO74631.1 - 0.11 11.3 0.3 0.19 10.5 0.2 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.8 CDO74632.1 - 5.2e-14 52.1 0.2 1.3e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 CDO74632.1 - 1e-06 28.8 0.0 2e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 CDO74632.1 - 3e-05 24.5 0.1 7.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CDO74632.1 - 0.00025 21.1 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 CDO74632.1 - 0.0022 17.3 0.3 0.0037 16.6 0.2 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 CDO74632.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 CDO74632.1 - 0.087 12.5 0.5 0.18 11.5 0.1 1.7 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family ACBP PF00887.14 CDO74634.1 - 8.9e-07 28.4 0.4 0.0076 15.8 0.0 2.4 1 1 1 2 2 2 2 Acyl CoA binding protein ADH_zinc_N PF00107.21 CDO74635.1 - 1.4e-18 66.7 0.1 2.1e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO74635.1 - 3.1e-11 43.0 1.8 8.4e-11 41.5 1.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ThiF PF00899.16 CDO74635.1 - 0.0091 15.8 0.5 0.076 12.8 0.4 2.2 2 0 0 2 2 2 1 ThiF family 2-Hacid_dh_C PF02826.14 CDO74635.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Vfa1 PF08432.5 CDO74636.1 - 2.3e-38 132.0 0.2 2.7e-38 131.7 0.2 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 BsuBI_PstI_RE PF06616.6 CDO74636.1 - 0.011 14.5 0.8 0.029 13.1 0.4 1.6 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease C-terminus ATP-synt_E PF05680.7 CDO74636.1 - 0.013 15.4 4.8 0.027 14.4 3.3 1.5 1 0 0 1 1 1 0 ATP synthase E chain U79_P34 PF03064.11 CDO74636.1 - 0.055 12.9 5.4 0.063 12.7 3.7 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Packaging_FI PF14000.1 CDO74636.1 - 0.26 11.5 5.3 0.44 10.7 3.7 1.3 1 0 0 1 1 1 0 DNA packaging protein FI SAPS PF04499.10 CDO74636.1 - 0.28 9.7 1.5 0.3 9.6 1.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_polI_A34 PF08208.6 CDO74636.1 - 0.33 10.6 14.5 0.44 10.1 10.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FAM176 PF14851.1 CDO74636.1 - 0.42 10.2 4.4 0.56 9.8 3.1 1.2 1 0 0 1 1 1 0 FAM176 family Sec62 PF03839.11 CDO74636.1 - 0.46 9.8 9.2 0.63 9.4 6.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Rtf2 PF04641.7 CDO74636.1 - 0.46 9.6 11.6 0.086 12.0 5.8 1.4 2 0 0 2 2 2 0 Rtf2 RING-finger TP53IP5 PF15331.1 CDO74636.1 - 0.5 10.2 5.4 0.63 9.9 3.7 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 FKBP_N PF01346.13 CDO74636.1 - 0.73 9.8 7.8 1.2 9.2 5.4 1.3 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase NARP1 PF12569.3 CDO74636.1 - 1.4 7.6 9.6 1.7 7.3 6.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3987 PF13148.1 CDO74636.1 - 1.7 7.1 6.6 2.4 6.6 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CDC45 PF02724.9 CDO74636.1 - 1.9 6.4 6.3 2.2 6.2 4.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3365 PF11845.3 CDO74636.1 - 2.6 7.8 5.7 3 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) NPR3 PF03666.8 CDO74636.1 - 3.9 5.9 5.8 4.8 5.5 4.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nucleoside_tran PF01733.13 CDO74637.1 - 4.1e-46 157.5 10.4 4.1e-46 157.5 7.2 1.6 2 0 0 2 2 2 1 Nucleoside transporter Retrotrans_gag PF03732.12 CDO74638.1 - 1.8e-07 31.1 1.1 7.1e-07 29.2 0.1 2.4 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO74638.1 - 7.9e-06 25.5 3.6 1.6e-05 24.6 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CDO74638.1 - 0.0013 18.2 0.2 0.0025 17.2 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.22 CDO74639.1 - 2.2e-09 36.9 0.0 5.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 CDO74639.1 - 2.8e-08 33.7 0.0 3.5e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CDO74639.1 - 0.00011 22.6 0.0 0.00026 21.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO74639.1 - 0.00014 21.6 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 CDO74639.1 - 0.035 13.6 0.0 0.44 10.1 0.0 2.4 2 1 0 2 2 2 0 Aspartyl protease rve PF00665.21 CDO74640.1 - 2.6e-09 37.1 0.0 4.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Pkinase_Tyr PF07714.12 CDO74643.1 - 2.1e-46 158.1 0.0 3.4e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDO74643.1 - 2.8e-42 144.6 0.0 7.4e-42 143.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CDO74643.1 - 1.6e-05 24.0 0.0 3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDO74643.1 - 0.00015 21.6 0.1 0.00043 20.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CDO74643.1 - 0.0003 20.2 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 CDO74643.1 - 0.0065 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.6 CDO74643.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Seadorna_VP7 PF07387.6 CDO74643.1 - 0.54 9.0 0.9 6.2 5.5 0.2 2.4 3 0 0 3 3 3 0 Seadornavirus VP7 DPBB_1 PF03330.13 CDO74644.1 - 3.8e-11 42.8 1.3 9.5e-11 41.5 0.9 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4473 PF14747.1 CDO74644.1 - 0.0017 18.5 0.0 0.0024 18.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) Barwin PF00967.12 CDO74644.1 - 0.0041 16.7 0.2 0.0053 16.4 0.2 1.2 1 0 0 1 1 1 1 Barwin family Gti1_Pac2 PF09729.4 CDO74645.1 - 6.4e-28 97.7 0.0 5.9e-24 84.8 0.1 2.2 2 0 0 2 2 2 2 Gti1/Pac2 family DNA_mis_repair PF01119.14 CDO74646.1 - 1.4e-18 66.4 0.0 4.2e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CDO74646.1 - 3.8e-14 52.4 0.1 9.7e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CDO74646.1 - 9.9e-14 51.0 0.1 2.2e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 CDO74646.1 - 1.1e-10 41.2 1.3 5.4e-06 26.0 0.1 3.0 2 1 0 2 2 2 2 MutL C terminal dimerisation domain DUF746 PF05344.6 CDO74647.1 - 0.099 12.1 0.1 0.38 10.3 0.0 2.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) GTSE1_N PF15259.1 CDO74648.1 - 0.25 11.3 4.7 0.37 10.7 3.3 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 GAGA_bind PF06217.7 CDO74648.1 - 0.5 10.2 4.1 0.65 9.9 2.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Zn_clus PF00172.13 CDO74648.1 - 2.8 7.9 7.5 12 5.9 1.0 1.9 1 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp-B-Hydro_N PF05279.6 CDO74648.1 - 5.6 6.7 13.5 7.2 6.3 9.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PVL_ORF50 PF07768.6 CDO74648.1 - 9.5 6.2 12.1 14 5.6 8.4 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family Methyltransf_1N PF02870.10 CDO74649.1 - 0.016 15.7 0.1 0.023 15.2 0.1 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Zn_clus PF00172.13 CDO74649.1 - 2.2 8.2 7.3 5.3 7.0 5.0 1.6 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain rve PF00665.21 CDO74650.1 - 1.3e-22 80.1 0.0 2.3e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO74650.1 - 2.4e-07 30.3 0.1 4.8e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CDO74650.1 - 0.00046 19.5 0.0 0.00085 18.6 0.0 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Imm47 PF15586.1 CDO74650.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 47 UBN2_2 PF14227.1 CDO74651.1 - 7.5e-10 38.4 0.1 1.5e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO74651.1 - 4.9e-05 23.1 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO74651.1 - 0.018 14.6 0.0 0.044 13.3 0.0 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO74651.1 - 0.14 11.6 0.9 0.53 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) zf-CCHC_4 PF14392.1 CDO74651.1 - 0.21 11.2 2.5 0.44 10.2 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Uds1 PF15456.1 CDO74651.1 - 2.3 8.2 6.3 0.47 10.4 0.1 2.6 3 0 0 3 3 3 0 Up-regulated During Septation rve PF00665.21 CDO74652.1 - 3.6e-22 78.7 0.0 6.3e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CDO74652.1 - 2.5e-09 36.6 0.3 5.2e-09 35.6 0.2 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 CDO74652.1 - 2.5e-09 36.7 0.0 1.2e-08 34.4 0.1 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO74652.1 - 0.00053 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 CDO74652.1 - 0.022 14.2 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain UBN2_3 PF14244.1 CDO74652.1 - 0.15 11.5 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MRI PF15325.1 CDO74653.1 - 0.022 15.7 0.3 0.041 14.8 0.2 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection 2-oxoacid_dh PF00198.18 CDO74654.1 - 3.8e-72 242.2 1.2 3.7e-71 239.0 0.0 2.1 1 1 1 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CDO74654.1 - 2.8e-20 71.7 0.2 5.7e-20 70.7 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CDO74654.1 - 2.1e-05 24.0 0.1 0.0017 17.9 0.0 2.7 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 CDO74654.1 - 0.00018 20.7 0.7 0.0041 16.3 0.1 2.1 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 CDO74654.1 - 0.00032 21.0 0.1 0.71 10.2 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 CDO74654.1 - 0.0037 16.9 0.2 0.0085 15.7 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein YL1 PF05764.8 CDO74654.1 - 0.17 11.4 7.3 0.28 10.7 5.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2360 PF10152.4 CDO74654.1 - 0.18 12.1 5.0 0.33 11.2 3.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Transposase_21 PF02992.9 CDO74655.1 - 9.2e-16 57.6 0.0 2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 Plasmodium_Vir PF05795.6 CDO74656.1 - 0.07 12.3 0.0 8 5.5 0.0 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein IncA PF04156.9 CDO74656.1 - 0.11 12.1 0.1 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 IncA protein IncA PF04156.9 CDO74658.1 - 0.0011 18.6 6.0 0.0038 16.8 4.2 1.9 1 0 0 1 1 1 1 IncA protein TPD52 PF04201.10 CDO74658.1 - 0.004 16.8 0.1 0.01 15.5 0.1 1.7 1 0 0 1 1 1 1 Tumour protein D52 family HMG_box PF00505.14 CDO74658.1 - 0.005 17.0 0.2 0.005 17.0 0.1 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box SlyX PF04102.7 CDO74658.1 - 0.0096 16.2 2.7 0.033 14.5 1.9 1.9 1 0 0 1 1 1 1 SlyX Spc7 PF08317.6 CDO74658.1 - 0.025 13.2 4.5 0.046 12.3 3.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.6 CDO74658.1 - 0.035 13.9 2.8 0.11 12.3 1.2 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3138 PF11336.3 CDO74658.1 - 0.088 10.9 1.8 0.15 10.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) AAA_13 PF13166.1 CDO74658.1 - 0.11 10.9 0.8 0.22 9.9 0.6 1.4 1 0 0 1 1 1 0 AAA domain HTH_38 PF13936.1 CDO74658.1 - 0.26 10.8 1.7 25 4.5 0.0 3.6 4 0 0 4 4 4 0 Helix-turn-helix domain Fib_alpha PF08702.5 CDO74658.1 - 0.72 9.9 8.1 0.062 13.4 1.6 2.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.1 CDO74658.1 - 7.3 5.4 9.3 0.097 11.6 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ATP-synt_Eps PF04627.8 CDO74661.1 - 0.094 12.2 0.3 0.22 11.0 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain Methyltransf_16 PF10294.4 CDO74663.1 - 4.8e-10 39.1 0.0 2.7e-06 26.9 0.0 2.3 1 1 1 2 2 2 2 Putative methyltransferase Abhydrolase_6 PF12697.2 CDO74664.1 - 1.3e-09 38.2 0.1 0.0012 18.8 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CDO74664.1 - 3.5e-08 33.1 0.0 1.6e-07 31.0 0.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 CDO74664.1 - 6.5e-07 29.2 0.0 7.6e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO74664.1 - 0.0089 15.8 0.0 0.036 13.9 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 CDO74665.1 - 2e-26 93.2 0.1 3.5e-26 92.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO74665.1 - 1.3e-12 47.8 0.0 1e-07 31.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO74665.1 - 3.4e-07 30.1 0.0 9.4e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO74665.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 CDO74665.1 - 0.12 12.6 0.1 0.24 11.5 0.0 1.7 1 1 0 1 1 1 0 Thioesterase domain XRN_N PF03159.13 CDO74666.1 - 5.1e-99 330.4 0.1 8.8e-99 329.6 0.1 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF2457 PF10446.4 CDO74667.1 - 4.8 5.8 13.3 7.2 5.2 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Acetyltransf_1 PF00583.19 CDO74669.1 - 1.2e-07 31.6 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CDO74669.1 - 7.8e-07 29.0 0.0 8e-05 22.5 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CDO74669.1 - 3e-05 24.0 0.0 4.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDO74669.1 - 0.002 18.2 0.0 0.005 16.9 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO74669.1 - 0.026 14.2 0.0 0.057 13.1 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein GMP_synt_C PF00958.17 CDO74670.1 - 1.4e-41 140.1 0.1 2.6e-41 139.2 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 CDO74670.1 - 1.5e-34 119.1 0.0 2.7e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 CDO74670.1 - 1.3e-11 43.8 0.1 2.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 CDO74670.1 - 2.5e-10 40.1 0.0 5.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 CDO74670.1 - 0.00058 18.5 0.1 0.001 17.7 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 CDO74670.1 - 0.00073 19.0 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 CDO74670.1 - 0.0032 16.9 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 CDO74670.1 - 0.0074 15.5 0.0 0.038 13.2 0.0 2.1 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC DUF2392 PF10288.4 CDO74670.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Arginosuc_synth PF00764.14 CDO74670.1 - 0.017 14.1 0.1 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 CDO74670.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 PP-loop family GST_N_3 PF13417.1 CDO74671.1 - 3.1e-14 52.9 0.0 5.7e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO74671.1 - 2.9e-11 43.2 0.0 5.6e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO74671.1 - 3.3e-08 33.5 0.0 7.1e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO74671.1 - 0.00033 20.4 0.0 0.00084 19.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PrpF PF04303.8 CDO74672.1 - 1.2e-67 228.3 0.5 1.3e-67 228.1 0.4 1.0 1 0 0 1 1 1 1 PrpF protein Abhydrolase_6 PF12697.2 CDO74673.1 - 2.9e-25 89.5 0.0 3.4e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO74673.1 - 1.2e-15 57.6 0.0 2.7e-15 56.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO74673.1 - 2.2e-09 37.2 0.0 4.6e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO74673.1 - 7.4e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CDO74673.1 - 0.0025 18.0 0.0 0.0049 17.1 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Peptidase_S10 PF00450.17 CDO74673.1 - 0.014 14.6 0.2 2.2 7.3 0.0 2.7 3 0 0 3 3 3 0 Serine carboxypeptidase PGAP1 PF07819.8 CDO74673.1 - 0.021 14.4 0.0 0.028 14.0 0.0 1.4 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 CDO74673.1 - 0.093 12.3 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 CDO74674.1 - 6.1e-27 94.9 0.1 7.6e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO74674.1 - 3.2e-17 62.8 0.0 4.6e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO74674.1 - 1.1e-08 34.9 0.0 2.8e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO74674.1 - 0.0041 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 CDO74674.1 - 0.005 16.4 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Whi5 PF08528.6 CDO74676.1 - 8.7e-06 25.2 0.7 1.3e-05 24.6 0.5 1.3 1 0 0 1 1 1 1 Whi5 like RVT_2 PF07727.9 CDO74678.1 - 3.5e-53 180.1 0.0 3.7e-52 176.7 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO74678.1 - 2.4e-14 53.4 0.1 6e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CDO74678.1 - 0.00024 20.6 0.0 0.00061 19.3 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CDO74678.1 - 0.0054 16.2 0.0 0.015 14.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain UBN2_3 PF14244.1 CDO74678.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO74678.1 - 0.1 12.6 0.8 0.21 11.5 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.14 CDO74679.1 - 5e-34 117.3 0.0 7.5e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CDO74679.1 - 2.1e-10 40.2 0.3 5.2e-10 39.0 0.2 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_ISL3 PF13542.1 CDO74679.1 - 0.066 12.4 0.0 0.36 10.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF2089 PF09862.4 CDO74679.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Cation_efflux PF01545.16 CDO74680.1 - 9.5e-52 175.8 7.5 9.5e-52 175.8 5.2 2.8 2 2 0 2 2 2 1 Cation efflux family Zip PF02535.17 CDO74680.1 - 0.0013 17.7 12.7 0.0013 17.7 8.8 4.6 2 1 2 4 4 4 1 ZIP Zinc transporter RNA_pol_L PF01193.19 CDO74680.1 - 0.046 12.8 0.0 0.12 11.4 0.0 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain EamA PF00892.15 CDO74680.1 - 4.4 7.3 35.1 0.71 9.9 3.1 4.6 4 1 0 4 4 4 0 EamA-like transporter family Rcd1 PF04078.8 CDO74681.1 - 2.2e-100 334.8 5.0 4.9e-90 300.9 0.9 2.0 1 1 1 2 2 2 2 Cell differentiation family, Rcd1-like SDH_alpha PF03313.10 CDO74682.1 - 5.4e-46 156.8 0.6 2.9e-35 121.6 0.0 2.3 1 1 1 2 2 2 2 Serine dehydratase alpha chain SDH_beta PF03315.10 CDO74682.1 - 4.1e-35 121.1 0.0 4.6e-34 117.7 0.0 2.3 1 1 0 1 1 1 1 Serine dehydratase beta chain SET PF00856.23 CDO74683.1 - 4.3e-08 33.6 0.0 3.4e-07 30.7 0.0 2.4 1 1 0 1 1 1 1 SET domain RhoGAP PF00620.22 CDO74684.1 - 2.8e-41 140.6 0.0 4.5e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 CDO74684.1 - 2.6e-13 50.0 0.0 5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CDO74684.1 - 2.5e-07 30.9 0.0 5.4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 CDO74684.1 - 0.003 17.5 0.0 0.0091 16.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PX PF00787.19 CDO74684.1 - 0.087 12.6 0.0 0.33 10.7 0.0 2.0 1 1 0 1 1 1 0 PX domain Cep57_CLD_2 PF14197.1 CDO74684.1 - 0.25 11.3 3.7 0.57 10.1 2.6 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 SHR3_chaperone PF08229.6 CDO74685.1 - 3.4e-23 81.6 0.1 5.8e-22 77.6 0.0 2.5 2 1 0 2 2 2 1 ER membrane protein SH3 DUF2681 PF10883.3 CDO74685.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) NicO PF03824.11 CDO74685.1 - 0.57 9.4 5.3 0.59 9.3 0.1 2.4 2 1 1 3 3 3 0 High-affinity nickel-transport protein DDE_3 PF13358.1 CDO74688.1 - 3.7e-08 33.2 0.0 5.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease Terminase_2 PF03592.11 CDO74688.1 - 0.089 13.0 0.0 0.73 10.1 0.0 2.0 2 0 0 2 2 2 0 Terminase small subunit zf-RanBP PF00641.13 CDO74691.1 - 4.2e-08 32.1 14.1 1.6e-05 23.8 1.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 CDO74691.1 - 0.33 10.7 6.8 1.9 8.3 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon UBN2_2 PF14227.1 CDO74693.1 - 3.8e-13 49.0 0.0 6.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO74693.1 - 4.3e-11 42.6 0.0 6.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO74693.1 - 6.4e-07 29.0 1.0 1.3e-06 28.0 0.7 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AAA_32 PF13654.1 CDO74693.1 - 0.081 11.5 0.6 0.12 11.0 0.4 1.1 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.18 CDO74693.1 - 0.14 12.1 6.8 0.55 10.2 4.7 1.9 1 1 0 1 1 1 0 Zinc knuckle rve PF00665.21 CDO74694.1 - 2.9e-19 69.3 0.0 4e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CDO74694.1 - 5.2e-06 26.0 0.0 2.1e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_2 PF07727.9 CDO74695.1 - 1.3e-79 266.6 0.0 1.8e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phi-29_GP4 PF05464.6 CDO74695.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Abhydrolase_6 PF12697.2 CDO74696.1 - 4.7e-26 92.0 1.7 6.3e-26 91.6 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO74696.1 - 1.4e-20 73.5 0.0 2.1e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO74696.1 - 1e-12 47.7 0.1 3.7e-12 45.9 0.1 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CDO74696.1 - 1.8e-07 30.6 0.0 0.0096 15.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CDO74696.1 - 5.7e-06 26.0 0.1 0.00011 21.8 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CDO74696.1 - 0.00035 20.2 0.0 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 CDO74696.1 - 0.0082 15.7 0.2 0.018 14.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CDO74696.1 - 0.013 15.7 0.1 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 CDO74696.1 - 0.019 14.3 0.1 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.7 CDO74696.1 - 0.025 13.1 0.2 19 3.6 0.0 3.0 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 CDO74696.1 - 0.039 13.2 0.0 4.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.8 CDO74696.1 - 0.045 13.3 0.0 0.098 12.2 0.0 1.7 2 1 0 2 2 2 0 PGAP1-like protein DUF1749 PF08538.5 CDO74696.1 - 0.073 11.9 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF900 PF05990.7 CDO74696.1 - 0.11 11.7 0.0 1.3 8.2 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pkinase PF00069.20 CDO74698.1 - 0.041 13.0 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.17 CDO74698.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family RRM_6 PF14259.1 CDO74699.1 - 1.1e-37 127.7 0.2 7.4e-11 41.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO74699.1 - 7.2e-31 105.6 1.4 1.7e-09 37.2 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO74699.1 - 9.1e-18 63.8 0.0 0.00027 20.7 0.0 5.0 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CDO74699.1 - 1.5e-05 24.8 0.1 0.081 12.7 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif DUF1866 PF08952.6 CDO74699.1 - 0.00027 20.5 0.1 1.2 8.6 0.0 3.2 3 1 1 4 4 4 2 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.1 CDO74699.1 - 0.0024 17.6 0.0 0.042 13.6 0.0 2.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif NID PF07292.8 CDO74699.1 - 0.006 16.5 0.0 1.2 9.2 0.0 3.6 4 0 0 4 4 4 1 Nmi/IFP 35 domain (NID) Optomotor-blind PF11078.3 CDO74699.1 - 0.65 10.3 6.4 1.8 8.9 0.8 3.5 3 0 0 3 3 3 0 Optomotor-blind protein N-terminal region ER_lumen_recept PF00810.13 CDO74701.1 - 2.1e-59 200.2 7.7 3.3e-59 199.6 5.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CDO74701.1 - 0.00022 20.6 3.8 0.52 9.8 0.0 3.9 3 1 1 4 4 4 2 PQ loop repeat Clat_adaptor_s PF01217.15 CDO74702.1 - 2.5e-18 66.1 0.0 4.2e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain N2227 PF07942.7 CDO74703.1 - 3.3e-62 209.8 0.0 4.8e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 CDO74703.1 - 2.6e-05 24.0 0.0 4.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO74703.1 - 0.004 17.6 0.0 0.014 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO74703.1 - 0.026 15.0 0.0 0.36 11.3 0.0 2.6 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_26 PF13659.1 CDO74703.1 - 0.094 12.7 0.0 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 CDO74704.1 - 8.9e-13 47.6 28.6 8.9e-13 47.6 19.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 CDO74704.1 - 2e-06 27.3 4.5 2e-06 27.3 3.1 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DIOX_N PF14226.1 CDO74705.1 - 5.4e-13 49.4 0.0 8.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO74705.1 - 1.3e-10 41.4 0.0 1.3e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Clathrin_lg_ch PF01086.12 CDO74706.1 - 2.4e-41 142.1 2.0 2.8e-41 141.8 1.4 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF4407 PF14362.1 CDO74706.1 - 0.41 9.5 4.9 0.47 9.3 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L30_N PF08079.7 CDO74706.1 - 2.3 8.3 15.3 4.4 7.3 10.6 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain LRR_8 PF13855.1 CDO74707.1 - 6.5e-11 41.8 13.5 5.1e-05 22.9 0.7 4.2 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 CDO74707.1 - 3.6e-06 26.4 16.8 0.00048 19.6 2.9 4.5 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDO74707.1 - 0.00037 20.1 8.6 3.3 8.0 0.5 6.1 6 0 0 6 6 6 2 Leucine Rich Repeat DUF218 PF02698.12 CDO74708.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 DUF218 domain Cupredoxin_1 PF13473.1 CDO74710.1 - 0.06 13.2 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain DUF1675 PF07897.6 CDO74711.1 - 6.6 6.5 9.3 1.1 9.0 3.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) DUF4203 PF13886.1 CDO74713.1 - 1.8e-09 37.4 27.0 1.8e-09 37.4 18.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) HEAT_EZ PF13513.1 CDO74714.1 - 3.4e-22 78.2 19.5 2.6e-11 43.6 0.0 10.7 8 2 4 12 12 12 2 HEAT-like repeat HEAT PF02985.17 CDO74714.1 - 1.7e-19 68.0 14.2 0.00011 21.9 0.0 9.5 10 0 0 10 10 9 4 HEAT repeat HEAT_2 PF13646.1 CDO74714.1 - 7.3e-19 67.8 0.7 1.1e-05 25.5 0.0 7.4 4 3 3 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.2 CDO74714.1 - 6.5e-08 32.8 0.0 0.028 14.8 0.0 3.9 4 0 0 4 4 3 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 CDO74714.1 - 8.6e-06 25.3 0.4 3.3 7.6 0.0 6.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 CDO74714.1 - 2e-05 24.5 0.1 0.24 11.2 0.0 4.9 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 CDO74714.1 - 0.0035 17.2 0.1 55 3.8 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 CDO74714.1 - 0.014 13.7 0.0 0.26 9.5 0.0 2.9 3 0 0 3 3 3 0 Adaptin N terminal region Cnd3 PF12719.2 CDO74714.1 - 0.088 11.7 0.2 4.9 6.0 0.0 2.9 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain DUF3437 PF11919.3 CDO74714.1 - 0.14 11.9 0.1 37 4.1 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) NOA36 PF06524.7 CDO74714.1 - 3.4 6.8 6.7 5.9 6.0 4.6 1.3 1 0 0 1 1 1 0 NOA36 protein Sugar_tr PF00083.19 CDO74715.1 - 1.2e-81 274.5 0.9 1.5e-81 274.2 0.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO74715.1 - 1.4e-14 53.6 29.9 5.5e-09 35.1 12.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TBPIP PF07106.8 CDO74716.1 - 0.028 13.9 13.5 0.23 11.0 1.2 3.0 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3573 PF12097.3 CDO74716.1 - 0.095 11.2 0.2 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) V_ATPase_I PF01496.14 CDO74716.1 - 0.18 9.6 1.7 0.28 9.0 1.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med9 PF07544.8 CDO74716.1 - 0.71 9.6 15.3 0.05 13.3 3.5 3.8 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.7 CDO74716.1 - 2 8.2 9.2 1 9.1 2.1 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 CDO74716.1 - 3.1 7.9 9.8 6.9 6.7 0.4 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family GAS PF13851.1 CDO74716.1 - 4.1 6.5 18.3 13 4.8 0.5 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 CDO74716.1 - 4.3 6.2 16.7 4.6 6.1 7.0 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 CDO74716.1 - 5.3 6.1 11.2 1.5 7.9 1.6 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF1843 PF08898.5 CDO74716.1 - 5.4 7.1 9.2 1.6 8.8 1.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) YlqD PF11068.3 CDO74716.1 - 7.1 6.6 11.0 3 7.8 4.3 2.7 2 1 1 3 3 3 0 YlqD protein DUF4404 PF14357.1 CDO74716.1 - 7.4 7.0 16.1 0.069 13.5 2.7 3.9 4 1 1 5 5 5 0 Domain of unknown function (DUF4404) DDE_3 PF13358.1 CDO74718.1 - 2.9e-17 62.7 0.0 4.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 CDO74718.1 - 0.009 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Methyltransf_11 PF08241.7 CDO74718.1 - 0.022 15.2 0.0 0.26 11.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain HTH_38 PF13936.1 CDO74718.1 - 0.047 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain RVT_2 PF07727.9 CDO74719.1 - 5.6e-79 264.5 0.0 7.9e-79 264.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S10 PF00450.17 CDO74722.1 - 1.7e-116 389.8 0.0 2.1e-116 389.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CDO74722.1 - 3.3e-05 23.8 0.2 0.0012 18.7 0.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hyd_65N_2 PF14498.1 CDO74723.1 - 4.4e-24 85.4 0.3 1.5e-20 73.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 CDO74723.1 - 0.0099 14.5 0.1 0.022 13.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Pkinase PF00069.20 CDO74724.1 - 1.8e-55 187.8 0.0 2.8e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74724.1 - 5.2e-20 71.6 0.2 8.5e-20 70.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO74724.1 - 0.0009 19.0 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CDO74724.1 - 0.0045 16.3 0.8 0.011 15.1 0.2 1.9 2 0 0 2 2 2 1 RIO1 family AAA PF00004.24 CDO74725.1 - 6.2e-37 126.7 0.0 1.8e-36 125.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.4 CDO74725.1 - 1.9e-33 115.2 0.0 3.2e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CDO74725.1 - 0.0012 18.4 0.3 0.0036 16.9 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_2 PF07724.9 CDO74725.1 - 0.0033 17.3 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CDO74725.1 - 0.0056 16.8 0.0 0.4 10.8 0.0 2.9 1 1 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 CDO74726.1 - 1.3e-113 377.8 0.0 1.8e-113 377.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CDO74726.1 - 2.6e-23 82.6 1.9 5.1e-23 81.6 1.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CDO74726.1 - 2.8e-14 53.0 2.7 8e-14 51.6 1.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 CDO74726.1 - 0.043 13.7 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain E2R135 PF11570.3 CDO74726.1 - 0.071 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Peptidase_M23 PF01551.17 CDO74726.1 - 0.12 12.4 0.0 22 5.1 0.0 3.6 4 0 0 4 4 4 0 Peptidase family M23 Fasciclin PF02469.17 CDO74727.1 - 3.2e-25 88.5 1.3 3.8e-13 49.5 0.0 4.0 3 1 0 3 3 3 3 Fasciclin domain IPPT PF01715.12 CDO74728.1 - 3e-48 164.0 0.6 1.2e-26 93.3 0.5 2.9 2 1 0 2 2 2 2 IPP transferase AAA_17 PF13207.1 CDO74728.1 - 3.9e-05 24.4 0.0 0.0001 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDO74728.1 - 4.4e-05 23.8 0.4 0.0066 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CDO74728.1 - 0.015 14.7 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CDO74728.1 - 0.065 13.3 0.0 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CDO74728.1 - 0.12 11.7 0.2 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.18 CDO74728.1 - 0.14 11.5 1.0 0.27 10.6 0.7 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 CDO74728.1 - 0.15 11.1 0.1 0.54 9.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin PRP38 PF03371.10 CDO74729.1 - 1.6e-67 226.4 0.3 2e-67 226.1 0.2 1.1 1 0 0 1 1 1 1 PRP38 family HEAT_2 PF13646.1 CDO74729.1 - 0.0073 16.5 0.0 0.033 14.4 0.0 2.0 2 0 0 2 2 2 1 HEAT repeats adh_short_C2 PF13561.1 CDO74730.1 - 2.2e-16 60.3 0.0 2.8e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO74730.1 - 1.6e-10 41.1 0.0 2.3e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase EST1_DNA_bind PF10373.4 CDO74731.1 - 1.7e-13 50.4 0.0 7.5e-13 48.3 0.0 2.2 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_4 PF13638.1 CDO74731.1 - 4.8e-10 39.6 0.7 1.3e-09 38.2 0.5 1.7 1 0 0 1 1 1 1 PIN domain DUF2717 PF10911.3 CDO74731.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) Nop14 PF04147.7 CDO74731.1 - 0.46 8.3 11.8 0.9 7.3 8.2 1.4 1 0 0 1 1 1 0 Nop14-like family EST1 PF10374.4 CDO74731.1 - 2.8 7.9 4.1 1.6 8.7 0.1 2.5 2 1 0 2 2 2 0 Telomerase activating protein Est1 NDK PF00334.14 CDO74732.1 - 1.6e-53 180.1 0.0 2.2e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase UCR_14kD PF02271.11 CDO74733.1 - 8.9e-41 137.9 0.9 1e-40 137.7 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Transketolase_N PF00456.16 CDO74734.1 - 8.6e-128 425.8 0.6 1.1e-114 382.7 0.0 2.2 1 1 1 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CDO74734.1 - 9.3e-44 149.0 0.0 1.8e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CDO74734.1 - 5.1e-09 36.1 0.1 1.4e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CDO74734.1 - 0.00013 21.0 0.1 0.00046 19.2 0.1 1.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 CDO74734.1 - 0.00026 19.7 0.0 0.00037 19.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF3939 PF13075.1 CDO74734.1 - 0.056 13.1 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) Peptidase_S48 PF03574.10 CDO74735.1 - 0.088 12.8 0.5 0.4 10.6 0.2 2.1 2 0 0 2 2 2 0 Peptidase family S48 rve PF00665.21 CDO74736.1 - 1.6e-26 92.8 0.0 4.6e-26 91.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 CDO74736.1 - 6.3e-16 58.0 0.0 1.2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO74736.1 - 2.3e-11 43.5 0.0 3.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO74736.1 - 5e-09 35.6 0.1 1.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CDO74736.1 - 0.0024 17.3 0.1 0.0081 15.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain BRF1 PF07741.8 CDO74736.1 - 7.6 6.8 6.4 25 5.1 0.7 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain MFS_1 PF07690.11 CDO74737.1 - 4.1e-27 94.8 39.9 2e-25 89.2 16.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO74737.1 - 2.3e-06 26.4 10.8 2.3e-06 26.4 7.5 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CDO74737.1 - 0.001 17.3 13.7 0.0071 14.5 9.5 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3180 PF11377.3 CDO74737.1 - 0.099 12.5 9.9 2.2 8.1 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) DUF3353 PF11833.3 CDO74737.1 - 0.24 10.8 6.9 1.5 8.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) Bacteriocin_IIc PF10439.4 CDO74737.1 - 0.5 10.5 8.9 2.8 8.1 6.2 2.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Pkinase PF00069.20 CDO74738.1 - 0.021 13.9 0.1 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain YrbL-PhoP_reg PF10707.4 CDO74738.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF500 PF04366.7 CDO74741.1 - 1.5e-45 153.7 0.0 2.4e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) RVT_2 PF07727.9 CDO74744.1 - 3.6e-20 71.9 0.2 5.8e-20 71.3 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CDO74744.1 - 0.063 12.6 0.3 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DAO PF01266.19 CDO74745.1 - 4.3e-44 150.8 0.1 5.4e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CDO74745.1 - 8.9e-05 22.6 0.0 0.048 13.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO74745.1 - 0.0006 19.7 0.1 0.0013 18.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CDO74745.1 - 0.0011 18.7 0.1 0.0044 16.8 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 CDO74745.1 - 0.042 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family SH3_9 PF14604.1 CDO74750.1 - 3.9e-31 106.3 2.3 2.8e-17 61.9 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CDO74750.1 - 1.1e-26 92.0 4.0 5.5e-15 54.4 0.3 2.3 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.15 CDO74750.1 - 5.8e-16 58.5 0.0 8.7e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.12 CDO74750.1 - 1e-15 56.9 0.2 3.9e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain MliC PF09864.4 CDO74750.1 - 0.14 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Mito_carr PF00153.22 CDO74751.1 - 3.4e-60 199.7 1.4 6.8e-24 83.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Retrotrans_gag PF03732.12 CDO74753.1 - 2.4e-12 46.7 0.0 3.8e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 CDO74756.1 - 7.3e-05 22.5 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDO74756.1 - 0.00016 22.0 0.0 0.41 11.1 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease Asp PF00026.18 CDO74756.1 - 0.003 16.8 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO74756.1 - 0.096 12.6 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal RVP PF00077.15 CDO74756.1 - 0.1 12.5 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease Retinal PF15449.1 CDO74756.1 - 0.29 8.7 3.9 0.41 8.2 2.7 1.0 1 0 0 1 1 1 0 Retinal protein Mitoc_L55 PF09776.4 CDO74757.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 WD40 PF00400.27 CDO74758.1 - 7.9e-13 47.7 0.0 0.00065 19.4 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.2 CDO74758.1 - 8.9e-07 28.5 1.8 9.5e-06 25.2 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDO74758.1 - 0.0014 18.2 0.5 0.0094 15.5 0.0 2.4 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 CDO74758.1 - 0.006 16.0 0.1 2.5 7.4 0.0 3.1 2 1 1 3 3 3 2 PQQ-like domain Hemerythrin PF01814.18 CDO74759.1 - 0.0039 17.3 2.6 0.0039 17.3 1.8 1.8 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain ATG27 PF09451.5 CDO74760.1 - 1.5e-07 30.8 0.0 2.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 CDO74760.1 - 0.087 12.5 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat APG12 PF04110.8 CDO74761.1 - 6.4e-21 74.3 0.0 8.7e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Cytochrome-c551 PF10643.4 CDO74761.1 - 0.082 12.1 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 TIR PF01582.15 CDO74761.1 - 0.12 11.8 0.1 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 TIR domain TgMIC1 PF11476.3 CDO74762.1 - 0.16 11.4 0.1 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 AMP-binding PF00501.23 CDO74763.1 - 1.8e-59 201.2 0.0 2.6e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 CDO74763.1 - 1.5e-30 107.0 0.1 4.3e-30 105.6 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 CDO74763.1 - 2.7e-11 43.5 0.2 1.5e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 CDO74763.1 - 1.7e-08 34.5 0.2 4.2e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.15 CDO74763.1 - 3e-07 30.6 0.0 8.3e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_5 PF12695.2 CDO74763.1 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_2 PF00891.13 CDO74764.1 - 4.6e-26 91.4 0.0 2.1e-23 82.7 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_12 PF08242.7 CDO74764.1 - 0.12 12.8 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF1469 PF07332.6 CDO74765.1 - 7.7 6.2 8.6 0.5 10.0 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Hemerythrin PF01814.18 CDO74766.1 - 5.9e-07 29.7 2.1 5.9e-07 29.7 1.4 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DELLA PF12041.3 CDO74766.1 - 0.11 12.1 0.1 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal RDD PF06271.7 CDO74767.1 - 0.15 11.9 0.2 0.15 11.9 0.2 1.9 2 1 0 2 2 2 0 RDD family Cytochrome-c551 PF10643.4 CDO74767.1 - 3.3 6.9 5.1 0.8 8.9 0.5 2.1 3 0 0 3 3 3 0 Photosystem P840 reaction-centre cytochrome c-551 Rad10 PF03834.9 CDO74768.1 - 5.4e-29 99.6 0.0 8.9e-29 98.9 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 CDO74768.1 - 1.6e-10 40.9 0.0 8.1e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.2 CDO74768.1 - 5e-07 29.5 0.0 3.1e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.2 CDO74768.1 - 0.00065 19.6 0.0 0.0014 18.5 0.0 1.6 1 1 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.20 CDO74768.1 - 0.048 13.9 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DUF605 PF04652.11 CDO74768.1 - 2.4 7.4 13.5 3.1 7.1 9.3 1.1 1 0 0 1 1 1 0 Vta1 like Suc_Fer-like PF06999.7 CDO74769.1 - 5.2e-25 88.8 0.5 3.3e-24 86.1 0.3 1.9 1 1 0 1 1 1 1 Sucrase/ferredoxin-like p450 PF00067.17 CDO74770.1 - 2.5e-06 26.3 0.0 3.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Prp19_bind PF06991.6 CDO74772.1 - 3.8e-67 226.4 32.7 3.8e-67 226.4 22.7 2.6 3 0 0 3 3 3 1 Splicing factor, Prp19-binding domain zf-CCHC PF00098.18 CDO74772.1 - 0.4 10.7 1.8 1.1 9.3 1.2 1.8 1 1 0 1 1 1 0 Zinc knuckle Fasciclin PF02469.17 CDO74773.1 - 2.9e-29 101.6 4.0 1.5e-18 67.0 0.3 2.4 2 0 0 2 2 2 2 Fasciclin domain Pyridox_oxidase PF01243.15 CDO74774.1 - 4.5e-06 26.5 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1283 PF06932.6 CDO74774.1 - 0.0064 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1283) DUF2798 PF11391.3 CDO74774.1 - 0.033 13.9 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) Fe-S_biosyn PF01521.15 CDO74775.1 - 5.3e-22 77.8 0.0 6.7e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF605 PF04652.11 CDO74775.1 - 7.4 5.8 14.2 9.5 5.4 9.9 1.1 1 0 0 1 1 1 0 Vta1 like FAP PF07174.6 CDO74775.1 - 8.9 5.5 20.0 12 5.0 13.9 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) O-FucT PF10250.4 CDO74776.1 - 0.19 10.7 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase SPRY PF00622.23 CDO74777.1 - 4.5e-24 84.9 0.1 7.8e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 CDO74777.1 - 6.6e-19 68.0 0.0 8.9e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CDO74777.1 - 0.002 17.8 0.1 0.0046 16.6 0.1 1.6 1 0 0 1 1 1 1 LisH CDK2AP PF09806.4 CDO74777.1 - 0.026 14.7 0.1 0.046 13.9 0.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Pacs-1 PF10254.4 CDO74777.1 - 0.19 10.3 0.1 0.35 9.4 0.1 1.3 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Actin PF00022.14 CDO74778.1 - 1.2e-37 129.2 0.0 2.3e-25 88.8 0.0 3.1 3 0 0 3 3 3 3 Actin IFP_35_N PF07334.8 CDO74778.1 - 0.069 13.1 1.1 0.17 11.8 0.7 1.6 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Ras PF00071.17 CDO74779.1 - 8e-63 210.6 0.0 9.4e-63 210.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO74779.1 - 6.9e-20 71.7 0.0 8.6e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO74779.1 - 2.5e-13 49.6 0.0 3.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO74779.1 - 2.4e-05 23.6 0.0 2.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDO74779.1 - 3.6e-05 23.2 0.0 9.2e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDO74779.1 - 0.00029 20.7 0.0 0.00039 20.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDO74779.1 - 0.003 16.8 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CDO74779.1 - 0.016 14.4 0.0 0.032 13.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CDO74779.1 - 0.03 14.3 0.0 0.068 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 CDO74779.1 - 0.031 13.4 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 CDO74779.1 - 0.032 13.7 0.0 0.1 12.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CDO74779.1 - 0.046 13.8 0.0 0.087 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CDO74779.1 - 0.054 13.6 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CDO74779.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.13 CDO74779.1 - 0.088 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Septin DOT1 PF08123.8 CDO74780.1 - 2.2e-58 196.9 0.0 1.7e-57 194.0 0.0 2.0 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 CDO74780.1 - 3e-05 24.5 0.0 5.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO74780.1 - 0.00037 20.4 0.0 0.00075 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO74780.1 - 0.0032 17.0 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO74780.1 - 0.034 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UvrD_C PF13361.1 CDO74781.1 - 7.1e-13 48.7 0.0 4.5e-10 39.5 0.0 3.3 4 0 0 4 4 4 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CDO74781.1 - 2.1e-09 37.1 4.2 1e-08 34.8 0.3 3.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CDO74781.1 - 1.2e-05 25.3 0.1 0.00035 20.6 0.0 3.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 CDO74781.1 - 0.0022 18.1 0.0 0.37 10.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 CDO74781.1 - 0.047 12.6 0.0 1.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TPR_11 PF13414.1 CDO74781.1 - 0.69 9.5 16.3 0.31 10.7 0.2 4.7 3 1 1 4 4 4 0 TPR repeat TPR_1 PF00515.23 CDO74781.1 - 0.76 9.4 16.0 0.57 9.8 0.5 4.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDO74781.1 - 6.4 6.8 12.8 15 5.7 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.24 CDO74783.1 - 7.9e-46 155.6 0.0 2.1e-45 154.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO74783.1 - 3.3e-27 94.1 0.0 2.6e-26 91.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CDO74783.1 - 6.1e-05 21.6 1.3 0.00021 19.8 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) AAA_19 PF13245.1 CDO74783.1 - 0.057 13.1 0.9 0.18 11.5 0.2 2.2 2 0 0 2 2 2 0 Part of AAA domain Porph_ging PF09697.5 CDO74783.1 - 1.6 8.8 0.0 1.6 8.8 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (Porph_ging) Oxysterol_BP PF01237.13 CDO74787.1 - 1.3e-83 280.4 1.5 1.5e-82 276.9 1.1 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein RGS PF00615.14 CDO74787.1 - 0.013 15.5 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain LepA_C PF06421.7 CDO74787.1 - 0.19 11.6 0.1 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus SBDS_C PF09377.5 CDO74788.1 - 7.8e-41 138.6 0.1 1.5e-40 137.8 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 CDO74788.1 - 7.6e-30 102.5 1.4 7.6e-30 102.5 0.9 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein BAR PF03114.13 CDO74789.1 - 2.9e-42 144.7 0.8 3.9e-42 144.3 0.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CDO74789.1 - 2.6e-16 58.7 0.5 4.9e-16 57.8 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CDO74789.1 - 1.2e-15 56.8 0.1 2.1e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CDO74789.1 - 3.9e-11 42.2 0.0 6.7e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 CDO74789.1 - 0.00013 21.3 3.2 0.0011 18.2 2.2 2.3 1 1 0 1 1 1 1 Vps5 C terminal like Arfaptin PF06456.8 CDO74789.1 - 0.0025 17.1 0.4 0.0046 16.3 0.0 1.6 2 0 0 2 2 2 1 Arfaptin-like domain DUF605 PF04652.11 CDO74789.1 - 6.6 6.0 13.9 10 5.4 9.6 1.2 1 0 0 1 1 1 0 Vta1 like Glyco_trans_1_4 PF13692.1 CDO74790.1 - 7.2e-21 74.7 0.0 1e-19 71.0 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CDO74790.1 - 3.3e-05 24.0 0.0 0.00018 21.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 CDO74790.1 - 7.1e-05 22.2 0.0 0.00038 19.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CDO74790.1 - 9.4e-05 22.6 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Nic96 PF04097.9 CDO74791.1 - 2.3e-139 465.3 0.0 3e-139 464.9 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 ST7 PF04184.7 CDO74791.1 - 0.022 13.0 2.0 0.035 12.3 1.4 1.2 1 0 0 1 1 1 0 ST7 protein Phage_int_SAM_1 PF02899.12 CDO74791.1 - 0.073 13.2 1.4 4.5 7.4 0.0 3.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain SMN PF06003.7 CDO74792.1 - 0.26 10.3 6.6 1.3 8.0 0.1 2.9 3 0 0 3 3 3 0 Survival motor neuron protein (SMN) FYVE PF01363.16 CDO74793.1 - 3e-17 62.2 2.8 3e-17 62.2 2.0 1.8 2 0 0 2 2 2 1 FYVE zinc finger zf-LITAF-like PF10601.4 CDO74793.1 - 6.9 6.6 8.5 16 5.4 2.0 2.5 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain PHD PF00628.24 CDO74795.1 - 4.1e-11 42.3 6.1 7.8e-11 41.5 4.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CDO74795.1 - 6e-06 25.4 2.5 6e-06 25.4 1.7 2.2 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 CDO74795.1 - 0.00019 21.0 2.1 0.00038 20.1 1.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-CW PF07496.10 CDO74795.1 - 0.026 14.2 3.0 0.056 13.1 2.1 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger C1_1 PF00130.17 CDO74795.1 - 0.25 11.1 4.4 0.066 12.9 0.7 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1675 PF07897.6 CDO74795.1 - 1.3 8.8 4.8 0.3 10.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) DNA_methylase PF00145.12 CDO74796.1 - 2.9e-17 62.8 0.0 3.7e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Het-C PF07217.6 CDO74796.1 - 0.055 11.6 0.0 0.098 10.8 0.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C eIF-5_eIF-2B PF01873.12 CDO74797.1 - 1.6e-43 147.3 0.1 3e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CDO74797.1 - 9.5e-29 99.1 1.0 3.5e-28 97.3 0.1 2.4 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon UQ_con PF00179.21 CDO74798.1 - 3.6e-18 65.3 0.0 5.2e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CDO74798.1 - 0.0017 18.2 0.0 0.0024 17.7 0.0 1.3 1 1 0 1 1 1 1 RWD domain Copper-fist PF00649.13 CDO74799.1 - 3.3e-21 74.1 0.4 3.3e-21 74.1 0.3 2.8 3 1 1 4 4 4 1 Copper fist DNA binding domain HA2 PF04408.18 CDO74800.1 - 1.6e-28 98.7 0.7 1.3e-27 95.8 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CDO74800.1 - 8.2e-23 80.4 0.0 3.8e-22 78.2 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CDO74800.1 - 8.8e-13 47.9 0.0 2.3e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO74800.1 - 9.7e-09 34.9 0.0 3.5e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CDO74800.1 - 2.3e-06 27.7 0.2 1.1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CDO74800.1 - 0.001 18.9 0.2 2.2 8.0 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 CDO74800.1 - 0.0014 18.3 0.1 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase T2SE PF00437.15 CDO74800.1 - 0.003 16.5 0.0 0.0085 15.0 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 CDO74800.1 - 0.0041 16.1 0.0 0.0071 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 CDO74800.1 - 0.0082 16.0 0.1 0.053 13.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 CDO74800.1 - 0.01 14.9 0.1 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 CDO74800.1 - 0.012 15.9 0.0 0.044 14.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.17 CDO74800.1 - 0.022 14.2 0.1 0.085 12.2 0.1 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 CDO74800.1 - 0.045 13.1 0.1 6.3 6.1 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain AAA_19 PF13245.1 CDO74800.1 - 0.046 13.4 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 CDO74800.1 - 0.048 12.5 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 CDO74800.1 - 0.051 13.2 0.1 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 CDO74800.1 - 0.054 12.7 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Miro PF08477.8 CDO74800.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 CDO74800.1 - 0.14 12.5 2.1 0.4 10.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain Porphobil_deam PF01379.15 CDO74801.1 - 8.5e-76 253.6 0.0 1.4e-75 252.9 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Nfu_N PF08712.6 CDO74801.1 - 4.2e-31 106.4 0.0 1.1e-30 105.0 0.0 1.8 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CDO74801.1 - 4.1e-22 77.7 0.1 9.5e-22 76.5 0.1 1.7 1 0 0 1 1 1 1 NifU-like domain Porphobil_deamC PF03900.10 CDO74801.1 - 7.7e-16 57.9 0.3 2e-15 56.6 0.2 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain ArsA_ATPase PF02374.10 CDO74802.1 - 3.8e-108 361.1 0.4 4.6e-108 360.8 0.3 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CDO74802.1 - 5.7e-14 51.9 0.0 1e-13 51.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CDO74802.1 - 1.6e-08 34.6 0.0 3.5e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CDO74802.1 - 4e-05 22.9 0.0 0.00014 21.1 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CDO74802.1 - 0.001 18.5 0.2 0.015 14.7 0.0 2.2 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 CDO74802.1 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.5 1 1 0 1 1 1 1 YhjQ protein AAA_25 PF13481.1 CDO74802.1 - 0.014 14.7 0.4 0.078 12.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CDO74802.1 - 0.021 14.5 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain MipZ PF09140.6 CDO74802.1 - 0.041 12.9 0.1 0.1 11.6 0.1 1.7 1 1 0 1 1 1 0 ATPase MipZ Ribosomal_S17e PF00833.13 CDO74806.1 - 1.9e-50 169.7 0.0 2.4e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.14 CDO74807.1 - 3.8e-27 94.6 0.1 5.4e-27 94.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 SNF2_N PF00176.18 CDO74808.1 - 1.3e-83 280.2 0.6 1.3e-83 280.2 0.4 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 CDO74808.1 - 1.2e-25 89.2 1.7 3.2e-25 87.8 0.1 2.5 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 CDO74808.1 - 3.7e-15 55.5 0.3 3.5e-14 52.4 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.8 CDO74808.1 - 2e-14 53.1 9.5 2e-14 53.1 6.6 2.6 3 0 0 3 3 3 1 HSA SnAC PF14619.1 CDO74808.1 - 2.5e-12 46.7 4.6 2.5e-12 46.7 3.2 4.5 4 2 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 CDO74808.1 - 2.4e-10 39.6 0.0 2.4e-10 39.6 0.0 2.4 3 0 0 3 3 3 1 QLQ ResIII PF04851.10 CDO74808.1 - 3.1e-07 30.4 0.0 3.1e-07 30.4 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Ku PF02735.11 CDO74809.1 - 1.9e-22 79.6 0.0 4.4e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CDO74809.1 - 7.1e-15 55.0 0.0 1.4e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 CDO74809.1 - 1.5e-09 37.7 0.1 3.4e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 CDO74809.1 - 3.2e-05 24.0 0.0 5.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CDO74809.1 - 0.00049 19.8 0.0 0.00097 18.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain ABC_tran PF00005.22 CDO74811.1 - 1.5e-46 158.0 0.1 3.9e-23 82.2 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 CDO74811.1 - 2.6e-23 81.6 3.9 2.6e-23 81.6 2.7 2.6 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 CDO74811.1 - 1.4e-19 71.2 4.3 1.5e-07 31.6 0.2 5.0 5 1 0 5 5 4 3 AAA domain AAA_17 PF13207.1 CDO74811.1 - 1.2e-08 35.8 3.4 0.0054 17.5 0.0 3.5 4 1 0 4 4 2 2 AAA domain SMC_N PF02463.14 CDO74811.1 - 6e-08 32.1 1.7 0.024 13.8 0.0 4.2 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 CDO74811.1 - 1.6e-07 31.2 0.1 0.0061 16.5 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 CDO74811.1 - 1.7e-07 31.4 1.9 0.054 13.6 0.0 4.2 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CDO74811.1 - 2e-07 30.4 0.1 0.0096 15.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 CDO74811.1 - 1.3e-06 28.7 2.8 0.16 12.2 0.0 4.7 5 0 0 5 5 5 2 AAA domain Miro PF08477.8 CDO74811.1 - 1.8e-06 28.4 0.0 0.1 13.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 CDO74811.1 - 2e-06 27.1 0.2 0.018 14.2 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CDO74811.1 - 4.2e-06 26.8 3.9 0.059 13.3 0.3 3.3 3 1 0 3 3 3 2 AAA ATPase domain NACHT PF05729.7 CDO74811.1 - 5.4e-06 26.1 0.0 0.11 12.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 CDO74811.1 - 1.5e-05 25.0 0.1 0.24 11.3 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CDO74811.1 - 2.7e-05 23.7 0.5 0.31 10.4 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain MobB PF03205.9 CDO74811.1 - 6.5e-05 22.6 0.0 0.11 12.1 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CDO74811.1 - 0.00014 20.7 0.1 0.061 12.0 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_14 PF13173.1 CDO74811.1 - 0.0005 19.9 0.1 5.2 6.9 0.0 3.9 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 CDO74811.1 - 0.00061 19.6 0.3 0.22 11.4 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 CDO74811.1 - 0.00071 19.4 0.0 0.18 11.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 CDO74811.1 - 0.0015 18.7 0.0 0.67 10.1 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CDO74811.1 - 0.0035 17.4 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 CDO74811.1 - 0.0072 15.7 0.0 5.3 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 CDO74811.1 - 0.008 16.5 18.1 0.04 14.2 0.1 4.4 5 0 0 5 5 4 1 AAA domain Arch_ATPase PF01637.13 CDO74811.1 - 0.012 15.2 1.9 4.9 6.7 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase NTPase_1 PF03266.10 CDO74811.1 - 0.016 14.9 0.0 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 CDO74811.1 - 0.023 14.4 0.6 5.1 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 CDO74811.1 - 0.029 13.8 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 CDO74811.1 - 0.038 13.7 6.1 0.34 10.6 0.1 3.3 4 0 0 4 4 3 0 Dynamin family cobW PF02492.14 CDO74811.1 - 0.06 12.7 0.1 13 5.2 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 CDO74811.1 - 0.17 11.6 12.1 0.2 11.4 0.1 3.8 4 1 0 4 4 3 0 Domain of unknown function DUF87 AAA_15 PF13175.1 CDO74811.1 - 3.8 6.4 18.2 2.1 7.3 0.1 4.7 4 2 2 6 6 6 0 AAA ATPase domain Saccharop_dh PF03435.13 CDO74812.1 - 5e-101 338.4 0.0 1.6e-100 336.8 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 CDO74812.1 - 2.6e-84 281.9 0.0 4.8e-84 281.1 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Shikimate_DH PF01488.15 CDO74812.1 - 1.2e-07 31.8 0.1 5.9e-06 26.4 0.0 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 CDO74812.1 - 1.4e-07 32.0 0.0 4e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO74812.1 - 1e-06 28.4 0.0 3.3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO74812.1 - 2.5e-06 27.4 0.2 4.6e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CDO74812.1 - 0.00036 19.9 0.0 0.0013 18.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CDO74812.1 - 0.00049 20.5 0.1 0.0028 18.1 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain NAD_binding_7 PF13241.1 CDO74812.1 - 0.0019 18.4 0.3 0.26 11.5 0.1 2.9 3 0 0 3 3 2 1 Putative NAD(P)-binding DUF2325 PF10087.4 CDO74812.1 - 0.0035 17.1 0.6 0.41 10.5 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2325) Methyltransf_11 PF08241.7 CDO74812.1 - 0.0049 17.3 0.0 0.083 13.3 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 CDO74812.1 - 0.019 14.1 0.1 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase DUF2016 PF09436.5 CDO74812.1 - 0.048 13.2 0.2 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) Macro_2 PF14519.1 CDO74812.1 - 0.19 10.8 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Macro-like domain Reprolysin_4 PF13583.1 CDO74813.1 - 1.5e-43 148.7 0.4 1.2e-42 145.8 0.3 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CDO74813.1 - 1.8e-41 142.2 5.0 1.8e-41 142.2 3.5 2.5 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CDO74813.1 - 1.1e-38 133.0 4.0 2.6e-38 131.8 1.2 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CDO74813.1 - 1.8e-19 70.4 0.5 6.9e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CDO74813.1 - 8.9e-17 61.0 21.8 8.9e-17 61.0 15.1 3.1 3 0 0 3 3 3 1 Disintegrin Reprolysin PF01421.14 CDO74813.1 - 1.3e-07 31.4 6.9 1e-06 28.4 4.8 2.4 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 CDO74813.1 - 0.00079 19.2 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M43 PF05572.8 CDO74813.1 - 0.011 15.3 1.2 0.022 14.3 0.0 1.9 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A Peptidase_M57 PF12388.3 CDO74813.1 - 1.5 8.0 6.4 4.4 6.5 2.5 2.5 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase Asp PF00026.18 CDO74814.1 - 5.3e-07 29.1 1.2 7.3e-07 28.7 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Brr6_like_C_C PF10104.4 CDO74815.1 - 4.1e-39 133.1 3.8 5.2e-39 132.8 2.6 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain ATP-synt_8 PF00895.15 CDO74815.1 - 0.44 10.8 3.5 1.2 9.4 0.4 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 PBP1_TM PF14812.1 CDO74815.1 - 1.5 9.1 7.2 0.21 11.8 1.5 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3792 PF12670.2 CDO74816.1 - 0.084 12.7 0.0 0.084 12.7 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3792) TPR_1 PF00515.23 CDO74817.1 - 4.1e-54 178.0 26.8 7e-08 31.7 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 CDO74817.1 - 6.8e-49 159.8 24.0 4.7e-05 23.0 0.0 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 CDO74817.1 - 1e-48 162.8 32.7 5.8e-12 45.0 0.7 6.7 2 2 5 8 8 8 8 TPR repeat TPR_8 PF13181.1 CDO74817.1 - 1.8e-36 121.1 15.9 0.0042 16.7 0.0 10.3 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 CDO74817.1 - 1.1e-30 105.5 18.9 6.2e-07 29.9 0.0 7.4 5 1 4 9 9 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 CDO74817.1 - 9.9e-30 100.3 14.6 0.00038 20.8 0.0 10.4 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 CDO74817.1 - 1.1e-29 102.1 22.4 5.1e-07 29.5 0.1 7.3 1 1 8 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.1 CDO74817.1 - 2.5e-28 95.8 15.6 0.001 19.0 0.0 9.7 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 CDO74817.1 - 1.9e-24 85.7 19.1 5.3e-07 29.8 1.5 7.2 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 CDO74817.1 - 3.6e-23 79.4 16.5 0.1 12.4 0.0 9.6 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_6 PF13174.1 CDO74817.1 - 4.3e-22 76.9 16.3 0.0035 17.6 0.0 10.4 10 0 0 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 CDO74817.1 - 3e-11 43.2 14.1 8.2e-05 22.6 0.6 5.1 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CDO74817.1 - 2.3e-10 40.1 15.2 0.017 14.9 0.1 6.0 1 1 5 7 7 7 5 Tetratricopeptide repeat TPR_21 PF09976.4 CDO74817.1 - 7.6e-08 32.4 5.4 0.0017 18.3 0.7 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 CDO74817.1 - 1.6e-07 30.6 9.5 0.31 10.0 1.0 5.4 1 1 5 6 6 6 3 Tetratricopeptide repeat SNAP PF14938.1 CDO74817.1 - 0.00028 20.1 12.5 0.28 10.3 1.2 4.5 1 1 3 4 4 4 2 Soluble NSF attachment protein, SNAP DUF2225 PF09986.4 CDO74817.1 - 0.0021 17.5 2.8 0.89 8.9 0.0 3.7 2 2 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.4 CDO74817.1 - 0.0048 16.2 0.6 9.8 5.5 0.0 4.2 2 2 3 5 5 5 0 26S proteasome subunit RPN7 ChAPs PF09295.5 CDO74817.1 - 0.013 14.2 0.2 6.3 5.4 0.0 2.5 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 CDO74817.1 - 0.042 13.7 1.2 37 4.3 0.0 4.2 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 CDO74817.1 - 0.044 13.8 7.0 0.091 12.8 0.0 4.5 4 2 3 7 7 6 0 Tetratricopeptide repeat Erf4 PF10256.4 CDO74818.1 - 4.1e-28 97.6 0.0 5.8e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Mito_fiss_reg PF05308.6 CDO74818.1 - 3.9 6.7 12.0 10 5.4 3.7 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF4218 PF13960.1 CDO74819.1 - 0.018 14.5 0.1 0.045 13.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) Arch_ATPase PF01637.13 CDO74821.1 - 9.9e-09 35.2 0.0 1.4e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 CDO74821.1 - 2.1e-07 31.0 0.0 2.8e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CDO74821.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CDO74821.1 - 0.037 13.2 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 CDO74821.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CDO74821.1 - 0.13 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 CDO74822.1 - 0.0058 16.3 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase ResIII PF04851.10 CDO74822.1 - 0.073 12.8 0.1 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA12 PF10443.4 CDO74822.1 - 0.077 11.4 0.0 0.14 10.6 0.0 1.4 2 0 0 2 2 2 0 RNA12 protein Piwi PF02171.12 CDO74823.1 - 3.4e-84 282.3 0.0 5.4e-84 281.7 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 CDO74823.1 - 6.4e-19 67.0 0.0 1.5e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 CDO74823.1 - 5.5e-12 45.1 0.0 2.2e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 PAZ domain Pkinase PF00069.20 CDO74826.1 - 5.6e-40 137.1 0.0 7.2e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74826.1 - 6.5e-17 61.4 0.0 9.2e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO74826.1 - 0.00029 20.6 0.6 0.0007 19.3 0.4 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CDO74826.1 - 0.0025 16.8 0.1 0.0046 16.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CDO74826.1 - 0.046 12.6 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Thr_synth_N PF14821.1 CDO74827.1 - 8.3e-27 93.0 0.0 2.1e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 CDO74827.1 - 3.8e-18 65.7 0.0 2.3e-17 63.2 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Dimer_Tnp_hAT PF05699.9 CDO74828.1 - 0.003 17.1 0.0 0.011 15.3 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Alba PF01918.16 CDO74828.1 - 0.02 14.4 0.0 6.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Alba WD40 PF00400.27 CDO74829.1 - 2.4e-56 185.7 21.9 5.7e-10 38.6 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 CDO74829.1 - 4.9e-11 42.1 3.4 9.9e-11 41.1 2.3 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CDO74829.1 - 1.4e-10 39.9 1.2 0.00056 18.1 0.0 4.3 2 1 2 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.28 CDO74829.1 - 1.5e-08 34.0 2.1 3.5e-08 32.8 1.4 1.7 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 CDO74829.1 - 0.00043 19.1 0.1 1.9 7.1 0.0 4.0 3 1 2 5 5 5 2 Nup133 N terminal like PQQ_2 PF13360.1 CDO74829.1 - 0.00084 18.8 0.7 0.035 13.5 0.2 2.9 2 1 1 3 3 3 1 PQQ-like domain AMP-binding PF00501.23 CDO74830.1 - 3.5e-53 180.4 0.1 4.8e-53 180.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CDO74830.1 - 1.2e-12 48.6 0.1 3.8e-12 46.9 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain rve PF00665.21 CDO74831.1 - 9.8e-21 74.0 0.0 1.8e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO74831.1 - 1.6e-07 30.8 0.1 3e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FlxA PF14282.1 CDO74832.1 - 8.3 6.4 9.0 7.7 6.5 0.2 2.3 2 0 0 2 2 2 0 FlxA-like protein zf-C2H2 PF00096.21 CDO74833.1 - 0.0014 18.8 1.2 0.0014 18.8 0.8 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO74833.1 - 0.04 14.2 1.5 0.04 14.2 1.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger RhoGEF PF00621.15 CDO74835.1 - 8.7e-38 129.9 0.0 1.4e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Ribosomal_S15 PF00312.17 CDO74835.1 - 5.6e-11 42.0 0.2 1.8e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein S15 PH PF00169.24 CDO74835.1 - 1.4e-06 28.4 0.0 4.6e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 PH domain MMR_HSR1 PF01926.18 CDO74836.1 - 2.6e-20 72.4 1.3 4.5e-16 58.8 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase NGP1NT PF08153.7 CDO74836.1 - 9.6e-08 32.0 0.0 2.6e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 NGP1NT (NUC091) domain FeoB_N PF02421.13 CDO74836.1 - 7.4e-07 28.5 0.5 4.5e-05 22.7 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CDO74836.1 - 7.9e-06 25.4 0.0 0.0016 17.9 0.0 3.1 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CDO74836.1 - 0.00025 20.2 0.0 0.0005 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 CDO74836.1 - 0.00035 19.8 0.0 0.14 11.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.18 CDO74836.1 - 0.1 12.4 6.4 4.6 7.0 0.1 4.0 3 1 1 4 4 4 0 Dynamin family Glyco_hydro_31 PF01055.21 CDO74837.1 - 3.9e-149 497.2 0.6 5e-148 493.5 0.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CDO74837.1 - 0.001 18.8 0.1 0.0051 16.6 0.0 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like Rotavirus_VP7 PF05868.6 CDO74837.1 - 0.0072 15.5 0.5 0.013 14.7 0.4 1.3 1 0 0 1 1 1 1 Rotavirus major outer capsid protein VP7 Chorion_2 PF03964.10 CDO74840.1 - 0.25 11.8 2.0 0.38 11.3 0.1 2.1 2 0 0 2 2 2 0 Chorion family 2 SAP PF02037.22 CDO74842.1 - 6.2e-09 35.1 0.4 9.9e-09 34.5 0.3 1.3 1 0 0 1 1 1 1 SAP domain GerE PF00196.14 CDO74842.1 - 0.13 11.6 0.7 0.2 10.9 0.5 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family CybS PF05328.7 CDO74844.1 - 7.6e-45 151.7 0.0 9.7e-45 151.4 0.0 1.1 1 0 0 1 1 1 1 CybS DPM2 PF07297.7 CDO74844.1 - 0.1 12.8 0.2 0.24 11.6 0.1 1.6 1 1 1 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TFIIA_gamma_N PF02268.11 CDO74846.1 - 5.6e-26 89.8 0.1 7.8e-26 89.4 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 CDO74846.1 - 5e-25 87.0 0.4 6.9e-25 86.6 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF2781 PF10914.3 CDO74847.1 - 1e-37 129.2 9.7 1.2e-37 128.9 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DSPc PF00782.15 CDO74848.1 - 4.6e-05 22.9 0.0 9.5e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CDO74848.1 - 0.002 18.4 0.0 0.0065 16.7 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CDO74848.1 - 0.014 14.7 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CDO74848.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate PC_rep PF01851.17 CDO74850.1 - 8.2e-28 95.0 20.4 5.5e-07 29.4 0.1 9.7 9 0 0 9 9 9 7 Proteasome/cyclosome repeat Ank PF00023.25 CDO74850.1 - 0.052 13.3 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat DUF4263 PF14082.1 CDO74851.1 - 0.066 13.1 0.3 0.066 13.1 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) RasGEF_N_2 PF14663.1 CDO74851.1 - 0.14 12.1 0.4 0.21 11.5 0.3 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF4662 PF15578.1 CDO74851.1 - 0.37 10.3 3.4 0.48 9.9 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) FlxA PF14282.1 CDO74851.1 - 1.1 9.2 8.1 1 9.3 0.1 2.2 2 0 0 2 2 2 0 FlxA-like protein Ribosomal_L18ae PF01775.12 CDO74853.1 - 0.14 12.0 0.1 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L18ae/LX protein domain 2Fe-2S_thioredx PF01257.14 CDO74854.1 - 0.13 11.8 0.4 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin Transposase_21 PF02992.9 CDO74857.1 - 4.8e-39 133.7 0.0 1e-38 132.7 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO74857.1 - 0.094 12.1 0.1 0.094 12.1 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4218) Glyco_hydro_3_C PF01915.17 CDO74858.1 - 1.7e-64 217.4 0.0 1.3e-63 214.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 CDO74858.1 - 6.7e-35 120.5 0.0 1.3e-32 113.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 CDO74858.1 - 1.4e-23 82.5 0.1 3e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 CDO74858.1 - 1.4e-10 40.9 0.0 2.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 PA14 domain DUF11 PF01345.13 CDO74858.1 - 0.15 12.1 5.1 0.55 10.3 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF11 Vel1p PF10339.4 CDO74858.1 - 0.16 11.1 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Yeast-specific zinc responsive DUF2340 PF10209.4 CDO74859.1 - 6.1e-46 155.5 1.3 7e-46 155.3 0.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Mis14 PF08641.7 CDO74860.1 - 0.0001 22.4 7.8 0.0002 21.4 5.4 1.6 1 0 0 1 1 1 1 Kinetochore protein Mis14 like HTH_40 PF14493.1 CDO74860.1 - 0.18 12.0 2.4 0.54 10.5 1.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain Cytochrom_B562 PF07361.6 CDO74860.1 - 0.2 12.0 3.1 4.9 7.6 0.1 2.9 1 1 2 3 3 3 0 Cytochrome b562 Nefa_Nip30_N PF10187.4 CDO74860.1 - 0.38 10.9 4.6 0.8 9.9 3.2 1.7 1 1 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4404 PF14357.1 CDO74860.1 - 1.6 9.1 11.2 15 6.0 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) FAM176 PF14851.1 CDO74860.1 - 1.7 8.3 6.8 0.47 10.1 2.5 1.7 2 0 0 2 2 2 0 FAM176 family MerR-DNA-bind PF09278.6 CDO74860.1 - 5.8 7.3 7.8 5.4 7.4 1.2 2.9 3 0 0 3 3 3 0 MerR, DNA binding Gar1 PF04410.9 CDO74861.1 - 1.3e-41 141.6 1.7 1.5e-41 141.4 0.0 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region AAA PF00004.24 CDO74862.1 - 3.6e-54 182.5 0.0 2.3e-44 150.7 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDO74862.1 - 2.8e-08 33.9 2.4 0.011 15.7 0.1 3.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 CDO74862.1 - 1.4e-06 28.5 0.1 0.019 15.1 0.0 4.1 2 2 1 3 3 3 1 AAA domain AAA_19 PF13245.1 CDO74862.1 - 2.4e-06 27.1 1.5 0.0016 18.1 0.0 3.3 3 0 0 3 3 2 1 Part of AAA domain AAA_17 PF13207.1 CDO74862.1 - 3.3e-06 27.8 0.0 0.014 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CDO74862.1 - 3.8e-06 26.6 0.1 0.017 14.8 0.0 3.1 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CDO74862.1 - 1.7e-05 23.9 0.0 0.0085 15.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CDO74862.1 - 3.1e-05 22.8 0.0 0.04 12.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 CDO74862.1 - 4e-05 23.1 0.1 0.0018 17.7 0.1 3.0 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CDO74862.1 - 7.2e-05 22.2 0.1 0.0033 16.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 CDO74862.1 - 0.00036 20.4 0.0 0.4 10.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 CDO74862.1 - 0.003 16.7 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 KaiC Sigma54_activat PF00158.21 CDO74862.1 - 0.0031 16.9 0.0 0.66 9.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_2 PF07724.9 CDO74862.1 - 0.0046 16.8 0.0 0.14 12.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CDO74862.1 - 0.0073 15.4 0.1 0.058 12.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 CDO74862.1 - 0.0095 15.5 0.0 0.58 9.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CDO74862.1 - 0.011 15.8 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 CDO74862.1 - 0.014 15.6 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CDO74862.1 - 0.017 15.0 0.0 0.49 10.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain PhoH PF02562.11 CDO74862.1 - 0.024 13.8 0.0 0.061 12.5 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein Parvo_NS1 PF01057.12 CDO74862.1 - 0.037 12.9 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 CDO74862.1 - 0.052 12.4 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 CDO74862.1 - 0.055 13.4 0.0 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 CDO74862.1 - 0.063 13.1 0.0 8.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_24 PF13479.1 CDO74862.1 - 0.074 12.6 0.1 0.22 11.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CDO74862.1 - 0.077 12.6 0.1 11 5.6 0.0 2.9 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.7 CDO74862.1 - 0.1 11.6 0.0 0.66 9.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Vps4_C PF09336.5 CDO74862.1 - 0.11 12.4 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 CDO74862.1 - 0.11 12.0 0.0 0.63 9.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IPT PF01745.11 CDO74862.1 - 0.32 10.1 0.4 9.5 5.3 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NB-ARC PF00931.17 CDO74862.1 - 0.35 9.6 0.0 1 8.1 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain PhoD PF09423.5 CDO74863.1 - 1e-45 156.1 0.1 1.2e-44 152.6 0.1 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase FH2 PF02181.18 CDO74864.1 - 1.1e-73 248.2 5.0 1.1e-73 248.2 3.5 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 CDO74864.1 - 2.1e-36 125.0 1.4 3.4e-36 124.3 0.1 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 CDO74864.1 - 4.7e-33 114.2 1.6 5.6e-33 114.0 0.1 1.9 2 0 0 2 2 2 1 Diaphanous FH3 Domain SPOUT_MTase_2 PF14419.1 CDO74864.1 - 0.04 13.0 0.1 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Peptidase_M1 PF01433.15 CDO74865.1 - 4.8e-99 332.0 0.0 3.1e-97 326.1 0.0 2.5 2 1 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 CDO74865.1 - 8.3e-56 189.5 1.6 1.2e-55 189.0 1.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CDO74865.1 - 1e-06 28.8 0.6 1.2e-05 25.3 0.4 2.5 1 1 0 1 1 1 1 Peptidase MA superfamily PRP3 PF08572.5 CDO74865.1 - 0.22 10.8 0.2 0.38 10.1 0.1 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) HECT PF00632.20 CDO74866.1 - 3e-90 302.6 0.0 5.5e-90 301.7 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CDO74866.1 - 8.9e-35 118.1 17.6 8.6e-12 44.6 1.4 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CDO74866.1 - 5.2e-13 48.6 0.1 1.5e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 C2 domain F-box-like PF12937.2 CDO74867.1 - 4.3e-07 29.5 0.1 1.9e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 CDO74868.1 - 1.3e-10 40.7 0.1 3.7e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 CDO74868.1 - 0.019 14.7 2.0 0.11 12.2 0.1 3.2 5 0 0 5 5 5 0 Leucine rich repeat F-box PF00646.28 CDO74868.1 - 0.048 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.2 CDO74868.1 - 0.085 12.5 1.6 1.6 8.3 0.5 3.2 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Far-17a_AIG1 PF04750.9 CDO74869.1 - 3.5e-06 26.3 15.0 6.5e-06 25.4 10.4 1.4 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein Pox_MCEL PF03291.11 CDO74870.1 - 7.1e-82 274.9 0.0 9.7e-82 274.4 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 CDO74870.1 - 8.4e-12 45.0 0.0 1.6e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO74870.1 - 4e-11 42.7 0.0 6.6e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO74870.1 - 1.4e-10 41.4 0.0 2.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO74870.1 - 1.5e-10 41.5 0.0 1e-09 38.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO74870.1 - 1e-08 35.5 0.0 2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO74870.1 - 1.5e-07 31.7 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO74870.1 - 0.00067 19.6 0.2 0.0021 18.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CDO74870.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 CDO74870.1 - 0.0039 16.1 0.0 0.0061 15.5 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 CDO74870.1 - 0.0085 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Rhodanese PF00581.15 CDO74871.1 - 3e-14 53.3 0.0 6.6e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DJ-1_PfpI PF01965.19 CDO74872.1 - 6.8e-23 80.7 0.0 1.5e-22 79.6 0.0 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family DUF4066 PF13278.1 CDO74872.1 - 0.024 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase DJ-1_PfpI_N PF13587.1 CDO74872.1 - 0.026 14.0 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of DJ-1_PfpI family GATase_3 PF07685.9 CDO74872.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Lipase_GDSL_2 PF13472.1 CDO74873.1 - 1.3e-27 97.0 0.0 1.6e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CDO74873.1 - 2.5e-26 92.9 0.0 3.2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3970 PF13113.1 CDO74873.1 - 0.047 13.3 0.2 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) F-box-like PF12937.2 CDO74874.1 - 1.1e-05 24.9 0.3 2.7e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 CDO74874.1 - 0.74 9.5 5.0 28 4.4 0.2 4.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) ATP12 PF07542.6 CDO74875.1 - 6.6e-34 116.4 0.0 8.9e-33 112.8 0.0 2.3 1 1 0 1 1 1 1 ATP12 chaperone protein IBN_N PF03810.14 CDO74875.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Importin-beta N-terminal domain MutS_V PF00488.16 CDO74876.1 - 9.6e-62 208.4 0.0 4.1e-59 199.8 0.0 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CDO74876.1 - 4.7e-37 127.7 2.8 7e-37 127.1 0.5 2.3 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.15 CDO74876.1 - 1.5e-11 44.2 0.0 3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CDO74876.1 - 1.9e-10 40.9 0.0 5.9e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CDO74876.1 - 2.2e-08 34.1 0.4 5.5e-08 32.8 0.3 1.7 1 0 0 1 1 1 1 MutS family domain IV DNA_pol_phi PF04931.8 CDO74877.1 - 2.4e-74 250.5 13.7 3.5e-74 249.9 9.5 1.2 1 0 0 1 1 1 1 DNA polymerase phi ZapA PF05164.8 CDO74877.1 - 0.0034 17.2 0.7 0.034 14.0 0.0 3.0 2 0 0 2 2 2 1 Cell division protein ZapA Nop14 PF04147.7 CDO74877.1 - 8.7 4.1 32.7 0.38 8.6 18.1 1.8 1 1 0 1 1 1 0 Nop14-like family EI24 PF07264.6 CDO74879.1 - 1.1e-32 113.2 20.6 1.7e-32 112.6 14.3 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Lipase_GDSL PF00657.17 CDO74879.1 - 4.8e-06 26.5 0.0 9.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CDO74879.1 - 0.00044 20.4 0.0 0.0041 17.2 0.0 2.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family BTB PF00651.26 CDO74879.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DsrH PF04077.7 CDO74879.1 - 0.092 12.4 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 DsrH like protein PAT1 PF09770.4 CDO74880.1 - 2.3 6.3 14.8 2.6 6.1 10.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOG2 PF10428.4 CDO74880.1 - 6.2 5.3 12.7 7.1 5.1 8.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Glycos_transf_1 PF00534.15 CDO74881.1 - 8.5e-21 74.1 0.0 1.4e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CDO74881.1 - 1.3e-09 38.3 0.0 2.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CDO74881.1 - 5.3e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 TF_Zn_Ribbon PF08271.7 CDO74882.1 - 0.0038 16.5 0.1 0.0083 15.4 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.14 CDO74882.1 - 0.023 14.4 0.1 0.054 13.3 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat RRN7 PF11781.3 CDO74882.1 - 0.083 12.4 1.2 0.17 11.4 0.8 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 tRNA_int_endo PF01974.12 CDO74883.1 - 2.3e-16 59.3 0.0 4.6e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF2514 PF10721.4 CDO74883.1 - 0.025 14.2 8.4 0.038 13.6 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) 2OG-FeII_Oxy_2 PF13532.1 CDO74885.1 - 5e-27 94.9 0.0 1.2e-24 87.1 0.0 2.1 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily LETM1 PF07766.8 CDO74886.1 - 4.9e-101 337.2 0.5 4.9e-101 337.2 0.4 2.2 2 1 0 2 2 2 1 LETM1-like protein SAP PF02037.22 CDO74886.1 - 9.4e-07 28.1 0.9 0.0024 17.3 0.0 4.2 4 0 0 4 4 4 1 SAP domain EF-hand_1 PF00036.27 CDO74886.1 - 0.00058 18.9 0.2 0.17 11.2 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 CDO74886.1 - 0.00088 19.3 0.1 0.018 15.1 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 CDO74886.1 - 0.0021 17.6 0.0 0.027 14.0 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CDO74886.1 - 0.0028 17.4 0.0 9.1 6.4 0.0 4.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 CDO74886.1 - 0.015 14.6 0.5 11 5.6 0.0 3.5 3 0 0 3 3 3 0 EF hand eIF-5a PF01287.15 CDO74886.1 - 0.13 12.2 1.7 1.9 8.4 0.1 2.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Peptidase_S46 PF10459.4 CDO74886.1 - 0.36 9.2 6.2 0.49 8.7 4.3 1.2 1 0 0 1 1 1 0 Peptidase S46 DALR_1 PF05746.10 CDO74886.1 - 1.9 8.4 7.4 6.3 6.7 3.8 2.6 2 0 0 2 2 2 0 DALR anticodon binding domain BTB PF00651.26 CDO74887.1 - 0.0044 16.9 0.0 0.076 13.0 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF740 PF05340.7 CDO74889.1 - 0.0009 17.7 2.2 0.0009 17.7 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF740) UPF0564 PF10595.4 CDO74889.1 - 0.0016 17.4 9.6 0.0016 17.4 6.7 1.4 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 vMSA PF00695.14 CDO74889.1 - 0.073 12.2 2.1 0.08 12.1 1.5 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Daxx PF03344.10 CDO74889.1 - 0.075 11.5 17.0 0.081 11.3 11.8 1.2 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 CDO74889.1 - 0.37 10.4 7.2 0.071 12.7 1.7 2.1 2 0 0 2 2 2 0 FAM176 family Suf PF05843.9 CDO74889.1 - 0.69 9.5 7.3 0.92 9.1 5.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ycf1 PF05758.7 CDO74889.1 - 0.72 7.5 7.3 0.76 7.4 5.0 1.1 1 0 0 1 1 1 0 Ycf1 DUF3530 PF12048.3 CDO74889.1 - 1.4 7.8 10.9 1.6 7.6 7.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) CDC73 PF05179.9 CDO74889.1 - 2 7.7 8.5 2.2 7.5 5.9 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family BSP_II PF05432.6 CDO74889.1 - 2.8 7.1 28.0 0.026 13.8 4.0 2.0 1 1 1 2 2 2 0 Bone sialoprotein II (BSP-II) PBP_sp32 PF07222.7 CDO74889.1 - 6.2 5.9 18.0 0.77 8.8 8.8 2.0 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Neur_chan_memb PF02932.11 CDO74889.1 - 6.9 6.4 6.8 9.9 5.9 4.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region U3_assoc_6 PF08640.6 CDO74891.1 - 0.065 12.9 0.2 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 MANEC PF07502.9 CDO74891.1 - 0.074 13.0 1.0 0.17 11.9 0.7 1.5 1 0 0 1 1 1 0 MANEC domain RVT_1 PF00078.22 CDO74892.1 - 7.3e-28 97.3 0.0 1.3e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CDO74892.1 - 4.8e-18 64.9 0.0 1.1e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CDO74892.1 - 2e-11 44.3 0.6 3.6e-11 43.4 0.4 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PAS_4 PF08448.5 CDO74893.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 PAS fold RVT_2 PF07727.9 CDO74894.1 - 4.2e-75 251.9 0.9 7.5e-75 251.0 0.6 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO74894.1 - 2.2e-25 89.0 0.0 5.1e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 CDO74894.1 - 2.1e-09 36.9 0.0 6.5e-08 32.1 0.0 2.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO74894.1 - 8e-07 28.8 0.0 0.00022 20.9 0.0 2.5 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type rve_3 PF13683.1 CDO74894.1 - 7.1e-05 22.2 0.0 0.00015 21.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CDO74895.1 - 3.1e-18 65.9 0.0 5.7e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO74895.1 - 3e-14 53.4 0.0 9e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 RNase H Exo_endo_phos_2 PF14529.1 CDO74895.1 - 5.5e-10 38.8 0.0 1.3e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CDO74895.1 - 0.00041 20.6 0.1 0.0043 17.3 0.0 2.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase IncA PF04156.9 CDO74895.1 - 1.2 8.7 3.6 16 5.0 1.4 2.3 2 0 0 2 2 2 0 IncA protein His_Phos_2 PF00328.17 CDO74897.1 - 2.9e-31 109.0 0.0 3.4e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Zip PF02535.17 CDO74899.1 - 1.8e-41 142.1 6.6 1.8e-41 142.1 4.6 1.8 2 0 0 2 2 2 1 ZIP Zinc transporter THUMP PF02926.12 CDO74900.1 - 2.3e-08 34.0 0.4 5.1e-08 32.9 0.3 1.6 1 0 0 1 1 1 1 THUMP domain HD PF01966.17 CDO74900.1 - 0.037 14.0 0.2 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 HD domain F_actin_cap_B PF01115.12 CDO74901.1 - 6.2e-103 343.1 0.0 7.5e-103 342.9 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit G-alpha PF00503.15 CDO74902.1 - 1.8e-113 379.1 1.1 1.3e-112 376.3 0.8 1.9 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CDO74902.1 - 9.7e-09 34.6 0.1 5.4e-05 22.4 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 CDO74902.1 - 0.015 14.8 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 CDO74902.1 - 0.067 12.3 0.1 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Pro_isomerase PF00160.16 CDO74903.1 - 7.9e-23 81.3 0.0 9.1e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CDO74904.1 - 6e-11 41.7 8.9 0.035 13.9 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Arrestin_N PF00339.24 CDO74904.1 - 5.6e-06 26.2 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CDO74904.1 - 2.3e-05 24.5 0.0 0.31 11.1 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain SH3_9 PF14604.1 CDO74905.1 - 2.3e-05 23.8 0.0 4.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CDO74905.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 SH3 domain PgaD PF13994.1 CDO74905.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 PgaD-like protein Gram_pos_anchor PF00746.16 CDO74905.1 - 0.79 9.5 2.9 2.6 7.9 1.1 2.3 2 0 0 2 2 2 0 Gram positive anchor Protocadherin PF08374.6 CDO74906.1 - 0.00072 19.2 0.4 0.0072 15.9 0.0 2.1 2 0 0 2 2 2 1 Protocadherin 7tm_1 PF00001.16 CDO74906.1 - 0.00078 18.6 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Mid2 PF04478.7 CDO74906.1 - 0.00087 18.7 0.0 0.0027 17.1 0.0 1.9 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Ctr PF04145.10 CDO74906.1 - 0.0035 17.3 0.3 0.043 13.8 0.0 2.4 2 0 0 2 2 2 1 Ctr copper transporter family Herpes_gE PF02480.11 CDO74906.1 - 0.0041 15.4 0.0 0.0077 14.5 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CDO74906.1 - 0.0075 16.6 0.0 0.026 14.9 0.0 1.9 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Vitellogenin_N PF01347.17 CDO74906.1 - 0.012 13.8 0.7 0.018 13.2 0.5 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region Amnionless PF14828.1 CDO74906.1 - 0.016 13.6 0.0 0.03 12.8 0.0 1.3 1 0 0 1 1 1 0 Amnionless Shisa PF13908.1 CDO74906.1 - 0.025 14.7 0.5 0.025 14.7 0.3 3.2 2 2 0 2 2 1 0 Wnt and FGF inhibitory regulator SKG6 PF08693.5 CDO74906.1 - 0.035 13.4 1.2 0.086 12.1 0.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2749 PF10907.3 CDO74906.1 - 4.2 7.3 6.5 11 5.9 0.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) Fungal_trans PF04082.13 CDO74907.1 - 7.2e-12 44.7 0.1 1.6e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CDO74907.1 - 6.6e-05 22.7 9.7 0.00012 21.8 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RICTOR_N PF14664.1 CDO74907.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term ABC_membrane PF00664.18 CDO74908.1 - 1e-50 172.7 21.0 1.6e-28 99.8 6.4 3.2 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 CDO74908.1 - 8e-46 155.7 0.1 6.7e-30 104.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CDO74908.1 - 5.1e-08 33.2 0.9 0.01 15.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CDO74908.1 - 1.8e-07 30.6 0.5 0.00035 19.8 0.3 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 CDO74908.1 - 0.016 13.7 0.0 0.031 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CDO74908.1 - 0.035 14.0 0.2 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gly-zipper_OmpA PF13436.1 CDO74908.1 - 0.053 13.1 0.6 0.18 11.4 0.4 1.8 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain C2 PF00168.25 CDO74909.1 - 5.3e-10 39.0 0.1 9.3e-10 38.2 0.1 1.4 1 0 0 1 1 1 1 C2 domain Sad1_UNC PF07738.8 CDO74910.1 - 2.8e-16 59.5 0.0 8.6e-10 38.5 0.0 2.6 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal Spc7 PF08317.6 CDO74910.1 - 0.0012 17.6 0.8 0.0019 16.9 0.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein IncA PF04156.9 CDO74910.1 - 0.011 15.2 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 CDO74910.1 - 0.09 11.6 1.1 0.2 10.5 0.7 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CTDII PF01556.13 CDO74911.1 - 1.1e-19 70.0 1.3 5.8e-19 67.7 0.0 2.5 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CDO74911.1 - 4e-11 42.8 16.6 6.4e-11 42.1 11.5 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CDO74911.1 - 0.0021 17.7 8.1 0.11 12.1 1.7 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Nol1_Nop2_Fmu PF01189.12 CDO74912.1 - 3.6e-15 56.0 0.1 2.6e-14 53.2 0.0 2.1 2 1 0 2 2 2 1 NOL1/NOP2/sun family zf-CCHC PF00098.18 CDO74913.1 - 1.2e-11 43.8 7.7 1.7e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CDO74913.1 - 6.5e-07 28.9 3.4 0.0022 17.6 1.0 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 CDO74913.1 - 9.1e-06 25.2 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CDO74913.1 - 0.00029 20.4 0.0 0.0007 19.1 0.0 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 CDO74913.1 - 0.00047 19.7 5.2 0.24 11.1 0.2 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CDO74913.1 - 0.0013 18.3 6.1 0.28 10.8 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDO74913.1 - 0.044 13.8 5.2 0.11 12.5 3.6 1.6 1 0 0 1 1 1 0 DnaJ central domain Acyl-CoA_ox_N PF14749.1 CDO74913.1 - 0.1 12.8 1.3 0.41 10.9 0.4 2.0 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal zf-CCHC_2 PF13696.1 CDO74913.1 - 0.51 9.8 0.0 0.51 9.8 0.0 3.3 2 1 1 3 3 3 0 Zinc knuckle CCDC-167 PF15188.1 CDO74913.1 - 2.2 8.3 5.5 0.83 9.6 0.2 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Helicase_C_3 PF13625.1 CDO74914.1 - 1.3e-19 70.2 0.1 6.3e-19 68.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO74914.1 - 2.8e-15 56.6 0.0 6.3e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CDO74914.1 - 4.1e-13 48.7 0.1 6.8e-13 48.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDO74914.1 - 3.4e-10 39.6 0.0 9.3e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO74914.1 - 1.5e-07 31.0 0.1 2.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 CDO74914.1 - 0.024 13.3 0.1 0.047 12.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 SBP_bac_6 PF13343.1 CDO74914.1 - 0.083 12.1 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Cys_Met_Meta_PP PF01053.15 CDO74915.1 - 8.9e-129 429.1 0.0 2e-128 428.0 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 CDO74915.1 - 5.7e-19 67.9 0.0 5.7e-19 67.9 0.0 3.1 4 0 0 4 4 4 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CDO74915.1 - 2.7e-05 24.2 0.5 0.00011 22.3 0.1 2.2 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 CDO74915.1 - 0.0013 17.9 0.0 0.0025 17.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Aminotran_1_2 PF00155.16 CDO74915.1 - 0.0014 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 CDO74915.1 - 0.0053 15.1 0.0 0.0088 14.3 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.12 CDO74915.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CDO74915.1 - 0.087 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Response_reg PF00072.19 CDO74916.1 - 2.5e-15 56.4 0.0 1.4e-13 50.8 0.0 2.7 2 1 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 CDO74916.1 - 7.1e-15 54.6 0.0 1.6e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 CDO74916.1 - 2.4e-14 53.0 0.1 9.1e-14 51.2 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 CDO74916.1 - 1.2e-08 35.2 0.1 2.1e-06 27.9 0.0 2.9 2 1 0 2 2 2 1 GAF domain GAF_3 PF13492.1 CDO74916.1 - 1e-05 25.6 0.0 0.18 11.8 0.0 3.0 2 1 0 2 2 2 2 GAF domain Abhydrolase_6 PF12697.2 CDO74917.1 - 7.7e-34 117.5 0.3 1e-33 117.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO74917.1 - 1.1e-13 51.2 0.2 1.8e-13 50.5 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO74917.1 - 2.5e-10 40.2 0.0 6.2e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family WYL PF13280.1 CDO74917.1 - 4.3e-05 23.4 0.0 0.00013 21.8 0.0 1.8 2 0 0 2 2 2 1 WYL domain Hydrolase_4 PF12146.3 CDO74917.1 - 0.00069 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 CDO74917.1 - 0.011 15.5 0.0 0.036 13.9 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_6 PF12697.2 CDO74918.1 - 5.7e-33 114.7 0.4 8.5e-33 114.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO74918.1 - 7.5e-17 61.6 0.1 6.4e-16 58.5 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO74918.1 - 1.7e-11 44.0 0.0 5.5e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO74918.1 - 0.00041 20.1 0.0 0.00095 18.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 CDO74918.1 - 0.0043 15.5 0.0 0.0062 15.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 CDO74918.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein AXE1 PF05448.7 CDO74918.1 - 0.13 10.7 0.0 1.4 7.3 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 CDO74919.1 - 4.9e-22 78.9 0.4 5.5e-22 78.7 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO74919.1 - 5.7e-12 45.6 0.1 7.4e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO74919.1 - 1e-08 35.0 0.0 1.3e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 CDO74919.1 - 4.5e-05 22.0 0.0 5.4e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 CDO74919.1 - 0.00026 20.7 0.0 0.0005 19.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 CDO74919.1 - 0.0056 15.2 0.0 0.008 14.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) adh_short PF00106.20 CDO74920.1 - 1.2e-19 70.8 0.8 1.7e-19 70.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO74920.1 - 3.8e-11 43.2 0.7 5.5e-11 42.7 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO74920.1 - 2.4e-05 24.0 0.4 3.5e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CDO74920.1 - 0.0016 18.4 0.4 0.0029 17.6 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CDO74920.1 - 0.005 16.2 0.1 0.008 15.6 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 CDO74920.1 - 0.017 14.7 0.3 0.036 13.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UBN2_2 PF14227.1 CDO74922.1 - 2.3e-09 36.8 0.0 4.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO74922.1 - 8.3e-09 35.1 1.6 4e-08 32.9 0.4 2.4 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO74922.1 - 1e-08 34.3 0.4 2.1e-08 33.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 CDO74922.1 - 7.4e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DDHD PF02862.12 CDO74922.1 - 0.63 9.7 5.0 1.1 9.0 3.5 1.3 1 0 0 1 1 1 0 DDHD domain DUF4292 PF14125.1 CDO74926.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) AChE_tetra PF08674.5 CDO74926.1 - 1 8.9 3.5 0.78 9.3 0.6 1.9 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain Transposase_21 PF02992.9 CDO74927.1 - 3.3e-13 49.2 0.0 5.8e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO74927.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) zf-RVT PF13966.1 CDO74929.1 - 0.0046 17.2 0.0 0.0063 16.7 0.0 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase MFS_1 PF07690.11 CDO74930.1 - 6.8e-31 107.2 30.0 6.8e-31 107.2 20.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO74930.1 - 0.00034 18.9 1.5 0.00066 18.0 1.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 CDO74930.1 - 0.04 12.3 26.0 0.58 8.4 2.9 2.9 1 1 1 2 2 2 0 MFS/sugar transport protein tRNA-synt_2c PF01411.14 CDO74931.1 - 3.3e-220 732.0 0.0 4.3e-220 731.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CDO74931.1 - 7.1e-17 61.0 0.7 3.5e-16 58.8 0.1 2.4 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CDO74931.1 - 2.3e-07 30.4 2.2 1e-06 28.3 1.5 2.2 1 0 0 1 1 1 1 DHHA1 domain Cytochrom_B_N_2 PF13631.1 CDO74931.1 - 0.21 11.3 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB zf-RING_5 PF14634.1 CDO74934.1 - 0.07 12.8 0.2 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 zinc-RING finger domain Aldo_ket_red PF00248.16 CDO74935.1 - 1.8e-42 145.1 0.0 2.2e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 CDO74936.1 - 2e-18 66.8 0.2 2.6e-18 66.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO74936.1 - 7.6e-17 61.8 0.0 1e-16 61.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO74936.1 - 1e-06 28.5 0.1 2.5e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Terpene_synth_C PF03936.11 CDO74937.1 - 2.2e-20 73.0 0.0 2.9e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Ank PF00023.25 CDO74938.1 - 3.9e-46 152.6 0.3 3.7e-12 45.3 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 CDO74938.1 - 4.2e-41 139.1 0.0 1.3e-13 51.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDO74938.1 - 2.7e-39 132.3 0.9 2.9e-14 52.7 0.0 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDO74938.1 - 1.4e-37 127.3 0.4 5.3e-14 52.2 0.0 5.1 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO74938.1 - 2.7e-35 116.8 0.0 5.1e-09 35.4 0.0 5.6 6 0 0 6 6 6 5 Ankyrin repeat Tfb2 PF03849.9 CDO74939.1 - 2.4e-49 167.9 0.0 3.1e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CDO74939.1 - 0.00014 21.5 0.0 0.00029 20.5 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Gti1_Pac2 PF09729.4 CDO74940.1 - 4.5e-43 147.0 3.0 8.2e-35 120.1 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Terpene_synth_C PF03936.11 CDO74941.1 - 2.4e-16 59.8 0.4 3.2e-16 59.3 0.2 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF410 PF04190.8 CDO74942.1 - 1.1e-21 77.6 0.0 2.6e-19 69.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF410) TPR_16 PF13432.1 CDO74942.1 - 0.026 15.2 3.3 1.3 9.7 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Arv1 PF04161.8 CDO74943.1 - 3.9e-12 46.5 0.4 5.9e-11 42.6 0.0 2.4 3 0 0 3 3 3 1 Arv1-like family Steroid_dh PF02544.11 CDO74944.1 - 2.2e-36 124.8 4.5 3.3e-36 124.2 3.1 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 CDO74944.1 - 1.2e-05 24.6 0.1 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 CDO74944.1 - 0.0026 18.3 0.0 0.0047 17.4 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF1295 PF06966.7 CDO74944.1 - 0.017 14.4 1.7 0.026 13.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) PEMT PF04191.8 CDO74944.1 - 0.04 14.0 0.4 0.081 13.0 0.3 1.6 1 0 0 1 1 1 0 Phospholipid methyltransferase UAE_UbL PF14732.1 CDO74944.1 - 0.076 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Rad60-SLD PF11976.3 CDO74944.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MIP PF00230.15 CDO74945.1 - 1.8e-40 138.8 7.2 2.4e-40 138.4 5.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3262 PF11660.3 CDO74945.1 - 3.6 7.7 7.2 0.27 11.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) Tannase PF07519.6 CDO74946.1 - 3e-103 346.0 1.6 4.5e-103 345.4 1.1 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 CDO74947.1 - 1.6e-30 106.6 0.1 2e-30 106.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO74947.1 - 4.6e-15 55.6 0.0 7.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO74947.1 - 1.8e-14 53.8 0.1 7.8e-12 45.2 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CDO74947.1 - 5.4e-09 36.6 0.0 7.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 CDO74947.1 - 9.2e-08 31.9 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 CDO74947.1 - 0.00021 21.0 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 CDO74947.1 - 0.00046 19.5 0.0 0.00072 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2048 PF09752.4 CDO74947.1 - 0.00097 18.1 0.1 0.29 9.9 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2048) Lipase_3 PF01764.20 CDO74947.1 - 0.0062 16.1 0.0 0.0091 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 CDO74947.1 - 0.027 14.0 0.0 0.07 12.6 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 CDO74947.1 - 0.037 12.8 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 CDO74947.1 - 0.067 11.9 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.15 CDO74947.1 - 0.088 12.2 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Lipase_2 PF01674.13 CDO74947.1 - 0.19 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) MAP7 PF05672.6 CDO74949.1 - 0.0047 16.3 42.7 0.0047 16.3 29.6 2.0 2 0 0 2 2 2 1 MAP7 (E-MAP-115) family Cupin_1 PF00190.17 CDO74951.1 - 1.4e-26 92.6 0.0 6.5e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 CDO74951.1 - 2.3e-24 84.6 0.8 5.3e-12 45.0 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 CDO74951.1 - 1.9e-09 36.7 0.1 0.00086 18.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 CDO74951.1 - 2.2e-06 27.3 0.0 0.00076 19.1 0.0 2.1 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase 3-HAO PF06052.7 CDO74951.1 - 0.00012 21.5 0.0 0.00034 20.0 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase ARD PF03079.9 CDO74951.1 - 0.00054 19.9 0.1 0.0067 16.3 0.0 2.1 2 0 0 2 2 2 1 ARD/ARD' family AraC_binding PF02311.14 CDO74951.1 - 0.0034 17.0 0.3 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_6 PF12852.2 CDO74951.1 - 0.014 15.0 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 0 Cupin Cupin_5 PF06172.6 CDO74951.1 - 0.076 12.9 0.0 37 4.2 0.0 3.2 2 1 1 3 3 3 0 Cupin superfamily (DUF985) FdtA PF05523.6 CDO74951.1 - 0.1 12.1 0.0 5.7 6.4 0.0 2.2 2 0 0 2 2 2 0 WxcM-like, C-terminal 2OG-FeII_Oxy_5 PF13759.1 CDO74951.1 - 0.12 12.6 0.1 1.9 8.8 0.0 2.7 3 1 1 4 4 3 0 Putative 2OG-Fe(II) oxygenase Cupin_8 PF13621.1 CDO74951.1 - 0.15 11.5 0.0 22 4.4 0.0 2.8 3 0 0 3 3 3 0 Cupin-like domain UCH PF00443.24 CDO74952.1 - 3.5e-55 187.0 0.2 4.4e-55 186.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDO74952.1 - 3.8e-24 85.6 0.3 1.3e-23 83.8 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_2 PF13240.1 CDO74952.1 - 0.24 10.9 7.7 3.2 7.3 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CDO74952.1 - 0.48 9.7 9.1 9 5.6 0.4 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 CDO74952.1 - 0.65 10.0 6.3 4.5 7.3 0.1 3.2 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.2 CDO74952.1 - 3.9 7.3 9.6 13 5.7 0.0 3.5 3 1 1 4 4 4 0 Double zinc ribbon YL1 PF05764.8 CDO74953.1 - 0.027 14.0 3.4 0.034 13.7 2.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Thg1C PF14413.1 CDO74954.1 - 5.5e-48 161.6 0.0 8.6e-48 161.0 0.0 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 CDO74954.1 - 4.9e-29 100.6 0.0 6.6e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Pterin_4a PF01329.14 CDO74956.1 - 0.099 12.4 0.2 0.23 11.2 0.1 1.7 1 1 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase Fork_head PF00250.13 CDO74957.1 - 3.7e-22 78.1 0.2 7.5e-22 77.1 0.1 1.4 1 0 0 1 1 1 1 Fork head domain Hamartin PF04388.7 CDO74957.1 - 2.5 6.6 6.9 3.5 6.1 4.8 1.1 1 0 0 1 1 1 0 Hamartin protein AIG2 PF06094.7 CDO74958.1 - 0.0042 17.5 0.0 0.0095 16.4 0.0 1.6 1 1 0 1 1 1 1 AIG2-like family tRNA-synt_1g PF09334.6 CDO74959.1 - 1e-101 340.4 0.1 1.4e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 CDO74959.1 - 4.3e-07 29.4 7.0 1e-06 28.2 4.9 1.6 1 0 0 1 1 1 1 WHEP-TRS domain Anticodon_1 PF08264.8 CDO74959.1 - 9.3e-07 28.7 0.0 2.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Nsp1_C PF05064.8 CDO74959.1 - 0.0088 15.6 1.1 0.02 14.5 0.7 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF2992 PF11208.3 CDO74959.1 - 0.051 13.4 0.6 7.6 6.4 0.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2992) Peptidase_C14 PF00656.17 CDO74960.1 - 2.6e-71 240.2 0.0 3.3e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Sugar_tr PF00083.19 CDO74961.1 - 4.7e-112 374.8 21.6 7e-112 374.2 15.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO74961.1 - 5.1e-29 101.0 51.0 2.6e-21 75.7 11.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDO74961.1 - 0.00019 19.9 37.1 0.005 15.2 8.6 3.6 2 2 0 3 3 3 2 MFS/sugar transport protein DUF4064 PF13273.1 CDO74961.1 - 3.9 7.6 13.3 1.1 9.3 1.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) UvrD_C PF13361.1 CDO74962.1 - 2.9e-69 234.1 0.0 8.2e-69 232.7 0.0 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CDO74962.1 - 6.4e-63 212.9 0.0 1.1e-62 212.1 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CDO74962.1 - 5.3e-14 52.2 0.0 2.4e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CDO74962.1 - 2.2e-13 49.7 0.0 4.6e-12 45.5 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 CDO74962.1 - 4.2e-08 33.0 0.5 0.033 13.6 0.0 3.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 CDO74962.1 - 1.3e-05 24.7 0.0 0.00041 19.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 CDO74962.1 - 0.00019 21.0 0.0 0.00051 19.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CDO74962.1 - 0.001 18.7 0.0 0.061 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain PMP22_Claudin PF00822.15 CDO74962.1 - 0.0073 15.9 0.4 0.015 14.9 0.3 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF2075 PF09848.4 CDO74962.1 - 0.11 11.4 0.0 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) HSP20 PF00011.16 CDO74963.1 - 3.4e-10 39.7 0.0 6.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Asp PF00026.18 CDO74964.1 - 2.1e-57 194.7 0.0 1.2e-55 188.9 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO74964.1 - 1.3e-09 38.1 0.2 2.6e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO74964.1 - 0.0015 18.9 0.7 0.096 13.2 0.1 3.2 2 1 0 2 2 2 1 Aspartyl protease Metallophos PF00149.23 CDO74965.1 - 6.3e-07 28.9 0.0 5.5e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase BSP_II PF05432.6 CDO74965.1 - 0.00011 21.6 0.9 0.00011 21.6 0.6 1.6 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Metallophos_2 PF12850.2 CDO74965.1 - 0.0028 17.5 0.0 0.0064 16.3 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Nop14 PF04147.7 CDO74965.1 - 0.031 12.2 3.0 0.042 11.7 2.1 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CDO74965.1 - 0.25 10.5 6.6 0.37 10.0 4.6 1.2 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.5 CDO74965.1 - 0.72 10.1 13.0 1.3 9.3 4.8 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2890 PF11081.3 CDO74965.1 - 1.5 8.8 8.1 6.1 6.8 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Sigma70_ner PF04546.8 CDO74965.1 - 1.9 8.0 7.5 0.22 11.0 1.4 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.6 CDO74965.1 - 3.9 7.2 5.7 2.4 7.9 2.1 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal S-antigen PF05756.6 CDO74965.1 - 6.1 6.8 8.5 0.82 9.6 2.0 2.1 2 0 0 2 2 2 0 S-antigen protein Cupin_1 PF00190.17 CDO74966.1 - 9.7e-31 106.1 0.0 2.9e-14 52.7 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 CDO74966.1 - 5.7e-27 93.0 0.1 4.5e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 CDO74966.1 - 3.9e-09 35.7 0.0 0.00024 20.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 CDO74966.1 - 1.3e-07 31.3 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.14 CDO74966.1 - 4.4e-06 26.4 0.1 0.00024 20.7 0.0 2.5 2 0 0 2 2 2 1 AraC-like ligand binding domain Pirin_C PF05726.8 CDO74966.1 - 0.0047 16.9 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain 3-HAO PF06052.7 CDO74966.1 - 0.0049 16.3 0.0 0.12 11.8 0.0 2.4 2 1 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase GPI PF06560.6 CDO74966.1 - 0.02 13.9 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Ectoine_synth PF06339.7 CDO74966.1 - 0.023 14.6 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Ectoine synthase FdtA PF05523.6 CDO74966.1 - 0.099 12.1 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 WxcM-like, C-terminal SET PF00856.23 CDO74967.1 - 0.059 13.6 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 SET domain PET PF06297.9 CDO74967.1 - 0.12 12.0 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 PET Domain Transketolase_N PF00456.16 CDO74968.1 - 7.9e-18 64.3 2.2 7.5e-17 61.1 1.5 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 CDO74968.1 - 3.3e-09 36.7 0.0 7.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 CDO74968.1 - 1.4e-05 24.7 0.5 2.9e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 CDO74968.1 - 5.2e-05 22.8 0.1 0.00024 20.7 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 CDO74968.1 - 0.001 17.8 0.0 0.0016 17.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component ADH_N PF08240.7 CDO74969.1 - 6.3e-24 83.8 2.2 1.1e-23 83.0 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO74969.1 - 7.5e-19 67.5 0.0 1.2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO74969.1 - 6.6e-05 23.7 0.0 0.00013 22.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CDO74969.1 - 0.008 16.1 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding IBD PF10416.4 CDO74969.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD ELFV_dehydrog PF00208.16 CDO74969.1 - 0.093 12.2 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HgmA PF04209.8 CDO74970.1 - 7.6e-125 416.6 0.0 3.5e-115 384.7 0.0 2.0 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase F-box-like PF12937.2 CDO74971.1 - 2.1e-05 24.1 2.6 6.1e-05 22.6 1.8 1.8 1 0 0 1 1 1 1 F-box-like Aminotran_5 PF00266.14 CDO74972.1 - 5.5e-17 61.5 0.0 1.6e-10 40.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.16 CDO74972.1 - 0.029 13.3 0.0 5.5 5.8 0.0 2.8 3 0 0 3 3 3 0 Aminotransferase class I and II PRK PF00485.13 CDO74973.1 - 8.2e-52 175.5 0.0 1.1e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 CDO74973.1 - 9.7e-45 152.3 0.0 8.6e-42 142.6 0.0 3.1 2 1 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_18 PF13238.1 CDO74973.1 - 4.2e-05 23.8 0.1 0.00015 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO74973.1 - 0.00024 20.7 0.1 1.1 9.0 0.0 3.5 3 0 0 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 CDO74973.1 - 0.0011 19.8 0.1 0.0031 18.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDO74973.1 - 0.0013 18.6 0.0 0.0036 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CDO74973.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin CoaE PF01121.15 CDO74973.1 - 0.058 12.7 1.3 0.71 9.2 0.3 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase UPF0079 PF02367.12 CDO74973.1 - 0.15 11.7 0.0 0.49 10.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2392 PF10288.4 CDO74974.1 - 7e-11 42.4 0.0 1.9e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2392) Na_Ca_ex PF01699.19 CDO74975.1 - 4.9e-25 87.7 16.8 7.2e-18 64.5 6.1 2.7 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Peptidase_M48 PF01435.13 CDO74977.1 - 1.6e-18 67.1 0.0 2.7e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_MA_2 PF13485.1 CDO74977.1 - 0.047 13.7 0.1 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily Svf1 PF08622.5 CDO74978.1 - 1.7e-90 303.2 0.0 2e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 Svf1-like MFS_1 PF07690.11 CDO74981.1 - 3e-21 75.5 44.0 3e-21 75.5 30.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO74981.1 - 2.6e-14 52.3 12.9 3.6e-10 38.6 3.1 2.6 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CDO74981.1 - 0.00016 20.3 11.4 0.00016 20.3 7.9 3.3 2 2 0 2 2 2 1 Sugar (and other) transporter Pkinase PF00069.20 CDO74982.1 - 3.5e-36 124.6 0.0 4.8e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74982.1 - 2.2e-12 46.6 0.0 3.1e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DSBA PF01323.15 CDO74983.1 - 2.2e-29 102.4 0.1 3e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 CDO74983.1 - 2.7e-06 27.4 0.3 1.5e-05 25.0 0.0 2.0 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 CDO74983.1 - 0.0046 16.7 0.4 0.07 12.9 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain Frag1 PF10277.4 CDO74984.1 - 5.3e-30 104.5 10.7 6.5e-30 104.2 7.4 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.8 CDO74984.1 - 7.7e-06 25.3 10.9 1.7e-05 24.2 7.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF998) Bax1-I PF01027.15 CDO74984.1 - 0.011 15.3 14.1 0.025 14.2 9.8 1.5 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 EI24 PF07264.6 CDO74984.1 - 0.015 14.6 6.4 0.35 10.2 1.4 2.5 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) 7TM_GPCR_Srh PF10318.4 CDO74984.1 - 0.2 10.4 6.4 0.12 11.1 3.4 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Cation_ATPase_C PF00689.16 CDO74984.1 - 0.86 9.1 9.2 1.2 8.5 6.4 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF1129 PF06570.6 CDO74984.1 - 0.94 8.7 4.7 1.5 8.1 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1183 PF06682.7 CDO74984.1 - 2 7.9 5.8 3.2 7.2 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) 7TMR-DISM_7TM PF07695.6 CDO74984.1 - 2.4 7.7 17.0 43 3.6 11.7 2.1 1 1 0 1 1 1 0 7TM diverse intracellular signalling ABC2_membrane_5 PF13346.1 CDO74984.1 - 4 6.6 16.2 0.52 9.5 6.9 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF2207 PF09972.4 CDO74984.1 - 4.7 5.6 14.3 0.38 9.2 1.2 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.19 CDO74984.1 - 8.5 5.7 8.7 9.9 5.5 3.2 2.0 1 1 1 2 2 2 0 Fatty acid desaturase DUF427 PF04248.7 CDO74985.1 - 2.5e-36 123.2 0.1 5.5e-30 102.8 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF427) DUF1080 PF06439.6 CDO74985.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) HEAT_2 PF13646.1 CDO74987.1 - 0.04 14.1 0.9 0.14 12.4 0.1 2.4 2 0 0 2 2 2 0 HEAT repeats Ribosomal_L10 PF00466.15 CDO74988.1 - 2.4e-26 91.5 0.4 4.2e-26 90.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CDO74988.1 - 1.3e-21 76.8 15.0 1.9e-21 76.2 7.2 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein S19 PF06756.6 CDO74988.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Chorion protein S19 C-terminal Methyltransf_23 PF13489.1 CDO74989.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO74989.1 - 0.06 13.8 0.2 0.72 10.3 0.1 2.8 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 CDO74989.1 - 0.062 12.6 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW p450 PF00067.17 CDO74990.1 - 5.9e-68 229.4 0.0 7.1e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNB PF00773.14 CDO74991.1 - 3.8e-50 170.9 0.0 5.7e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 RNB domain Pkinase PF00069.20 CDO74993.1 - 1.5e-46 158.6 0.0 4.9e-26 91.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO74993.1 - 2.9e-22 78.9 0.0 9.4e-12 44.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CDO74993.1 - 8.9e-08 31.4 0.0 0.00014 20.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CDO74993.1 - 1.9e-05 24.5 0.2 0.00031 20.5 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CDO74993.1 - 0.11 11.2 0.0 0.26 10.0 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase zf-C3HC PF07967.8 CDO74994.1 - 6.3e-26 90.7 0.0 1.5e-24 86.2 0.0 2.3 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.5 CDO74994.1 - 1.4e-15 56.8 1.1 5.6e-10 38.9 0.0 3.1 3 0 0 3 3 3 2 Rsm1-like DM PF00751.13 CDO74994.1 - 0.11 12.0 0.3 3.3 7.3 0.1 2.5 2 0 0 2 2 2 0 DM DNA binding domain DUF2370 PF10176.4 CDO74995.1 - 7.4e-58 195.6 0.0 1.3e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Glyco_transf_20 PF00982.16 CDO74996.1 - 9.5e-189 627.7 0.0 8.3e-142 472.9 0.0 1.9 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 CDO74996.1 - 0.018 14.5 0.2 4 6.8 0.0 2.7 2 1 0 2 2 2 0 Glycosyl transferases group 1 PP2C PF00481.16 CDO74997.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C COG6 PF06419.6 CDO74997.1 - 0.17 9.9 0.0 0.23 9.5 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Rep_fac_C PF08542.6 CDO74998.1 - 3.1e-17 62.3 0.6 7.1e-12 45.1 0.1 2.9 3 0 0 3 3 3 2 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CDO74998.1 - 4e-13 49.3 0.0 7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CDO74998.1 - 6.5e-06 26.3 0.9 1.8e-05 24.9 0.6 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 CDO74998.1 - 9.8e-05 21.9 0.3 0.00016 21.2 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 CDO74998.1 - 0.012 14.6 0.4 4.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CDO74998.1 - 0.013 15.4 1.1 0.52 10.2 0.7 2.4 1 1 0 1 1 1 0 AAA ATPase domain TSC21 PF15217.1 CDO74998.1 - 0.015 14.9 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 TSC21 family Bac_DnaA PF00308.13 CDO74998.1 - 0.017 14.7 1.0 0.37 10.4 0.3 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein Rad17 PF03215.10 CDO74998.1 - 0.018 13.7 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 CDO74998.1 - 0.019 14.4 1.0 0.53 9.6 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 CDO74998.1 - 0.022 14.9 1.9 0.13 12.3 0.8 2.4 2 1 0 2 2 2 0 AAA domain SNF2_N PF00176.18 CDO74998.1 - 0.052 12.3 0.2 0.084 11.6 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF3802 PF12290.3 CDO74998.1 - 0.064 13.5 2.1 0.065 13.5 0.2 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3802) DUF968 PF06147.6 CDO74998.1 - 0.21 11.4 2.4 2.5 7.9 1.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF968) Asp_protease_2 PF13650.1 CDO74999.1 - 0.0015 19.0 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CDO74999.1 - 0.037 13.5 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Abhydrolase_6 PF12697.2 CDO75001.1 - 6.8e-24 85.0 0.4 8.1e-24 84.7 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO75001.1 - 2.8e-11 43.4 0.0 6.3e-11 42.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO75001.1 - 8e-09 35.4 0.0 1.9e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CDO75001.1 - 0.00069 19.9 0.0 0.00097 19.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 CDO75001.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase MFS_1 PF07690.11 CDO75002.1 - 8.4e-29 100.3 45.1 7.2e-27 94.0 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pam17 PF08566.5 CDO75002.1 - 0.052 13.2 0.6 0.13 11.9 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 TraL PF07178.6 CDO75002.1 - 0.35 10.9 8.2 0.18 11.8 1.0 2.8 2 0 0 2 2 2 0 TraL protein DUF2034 PF10356.4 CDO75003.1 - 2.2e-26 92.1 0.1 1.9e-25 89.0 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Abhydrolase_6 PF12697.2 CDO75003.1 - 6.6e-06 26.1 0.0 9.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Mrr_cat PF04471.7 CDO75003.1 - 2.1e-05 24.3 0.0 0.00011 21.9 0.0 2.1 1 1 0 1 1 1 1 Restriction endonuclease RdRP PF05183.7 CDO75004.1 - 1.7e-107 360.5 0.0 2.2e-107 360.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Mob1_phocein PF03637.12 CDO75005.1 - 2.5e-26 92.4 0.1 4.5e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family Transp_cyt_pur PF02133.10 CDO75006.1 - 7.5e-33 113.7 30.1 7.2e-32 110.4 20.9 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4017 PF13209.1 CDO75007.1 - 0.02 14.6 0.4 0.03 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) WD40 PF00400.27 CDO75008.1 - 1.9e-16 59.2 11.2 2.4e-08 33.5 0.4 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat Kinetochor_Ybp2 PF08568.5 CDO75008.1 - 2.7e-14 52.3 0.0 3e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family, YAP/Alf4/glomulin Ribosomal_L7Ae PF01248.21 CDO75009.1 - 4.3e-28 96.6 2.9 5.3e-28 96.3 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.7 CDO75009.1 - 0.027 14.6 1.0 0.51 10.5 0.1 2.3 1 1 1 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF2042 PF09743.4 CDO75009.1 - 0.067 12.4 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) ABC_membrane_2 PF06472.10 CDO75010.1 - 6.9e-58 195.9 3.5 7.9e-36 123.6 0.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CDO75010.1 - 2.1e-16 60.4 0.0 4.4e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 CDO75010.1 - 0.039 13.6 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF3584 PF12128.3 CDO75010.1 - 0.063 10.6 1.1 0.48 7.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_16 PF13191.1 CDO75010.1 - 0.064 13.2 0.1 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 CDO75010.1 - 0.1 11.8 0.0 0.68 9.1 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Acetyltransf_8 PF13523.1 CDO75011.1 - 1.2e-33 116.1 0.2 2.5e-33 115.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CoxIIa PF08113.6 CDO75012.1 - 1.8 8.3 5.7 0.37 10.5 1.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family ADH_zinc_N PF00107.21 CDO75013.1 - 9.7e-32 109.2 0.0 2.2e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO75013.1 - 9.8e-16 58.8 0.1 2.3e-15 57.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SIS_2 PF13580.1 CDO75013.1 - 0.019 14.6 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 SIS domain adh_short_C2 PF13561.1 CDO75013.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 CDO75013.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FA_desaturase PF00487.19 CDO75015.1 - 4.7e-07 29.5 0.5 5.5e-07 29.3 0.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase XPG_I PF00867.13 CDO75016.1 - 1.4e-19 69.9 0.0 2.3e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CDO75016.1 - 0.0089 16.2 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CDO75016.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 XPG domain containing Yip1 PF04893.12 CDO75018.1 - 0.0028 17.1 1.8 0.0055 16.2 1.2 1.4 1 0 0 1 1 1 1 Yip1 domain DUF4231 PF14015.1 CDO75018.1 - 0.096 12.6 0.2 0.096 12.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Coatomer_WDAD PF04053.9 CDO75019.1 - 2.7e-153 510.9 0.0 4e-153 510.3 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 CDO75019.1 - 1.4e-54 180.1 0.9 4.2e-10 39.1 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CDO75019.1 - 1.4e-05 24.8 0.0 2 8.2 0.0 5.2 5 1 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 CDO75019.1 - 0.013 13.7 0.1 0.2 9.7 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CDO75019.1 - 0.047 13.1 2.0 2.5 7.5 0.2 3.4 2 1 0 3 3 3 0 PQQ-like domain Chitin_synth_2 PF03142.10 CDO75020.1 - 2.6e-232 771.9 0.1 3.4e-232 771.5 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CDO75020.1 - 1.4e-114 383.5 0.0 2.6e-114 382.7 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 CDO75020.1 - 7.8e-19 67.2 0.2 1.1e-12 47.6 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 CDO75020.1 - 2.7e-18 66.5 0.0 8.2e-14 51.9 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 CDO75020.1 - 1.9e-16 59.5 0.2 7.3e-16 57.6 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 CDO75020.1 - 2.6e-16 59.8 8.8 1.1e-15 57.9 6.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CDO75020.1 - 3.8e-09 36.4 0.1 4.8e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CDO75020.1 - 6.7e-05 22.2 0.0 0.0026 17.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 WD40 PF00400.27 CDO75023.1 - 4.3e-33 111.9 22.0 5.8e-09 35.5 0.2 8.7 9 0 0 9 9 9 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CDO75023.1 - 0.0022 16.8 0.0 0.04 12.6 0.0 2.1 1 1 0 1 1 1 1 Nup133 N terminal like TFIIIC_delta PF12657.2 CDO75023.1 - 0.034 13.8 0.1 0.64 9.6 0.1 3.0 2 2 1 3 3 3 0 Transcription factor IIIC subunit delta N-term PQQ_3 PF13570.1 CDO75023.1 - 0.17 12.1 8.3 16 5.9 0.0 5.9 6 2 1 7 7 7 0 PQQ-like domain NACHT PF05729.7 CDO75024.1 - 4.2e-09 36.2 0.0 1.8e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CDO75024.1 - 5.2e-08 33.0 2.0 1.8e-06 28.0 0.0 3.2 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CDO75024.1 - 4.9e-07 29.9 0.1 6.5e-05 23.0 0.0 3.4 3 1 1 4 4 4 1 AAA domain AAA PF00004.24 CDO75024.1 - 3.6e-06 27.2 0.0 0.0026 17.9 0.0 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 CDO75024.1 - 0.0004 19.3 0.0 0.00064 18.6 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 CDO75024.1 - 0.0019 17.8 0.0 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CDO75024.1 - 0.0021 17.8 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase AAA_25 PF13481.1 CDO75024.1 - 0.0025 17.2 0.1 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CDO75024.1 - 0.0031 16.4 0.0 0.011 14.6 0.0 1.9 2 1 0 2 2 2 1 NB-ARC domain MutS_III PF05192.13 CDO75024.1 - 0.0037 17.0 0.0 0.032 14.0 0.0 2.2 1 1 0 1 1 1 1 MutS domain III AAA_19 PF13245.1 CDO75024.1 - 0.022 14.4 0.0 0.061 13.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 CDO75024.1 - 0.075 13.3 0.1 0.36 11.1 0.0 2.1 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 CDO75024.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF1678 PF07913.6 CDO75024.1 - 0.09 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) APS_kinase PF01583.15 CDO75024.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 CDO75024.1 - 3.2 6.6 4.7 12 4.7 0.2 2.7 2 1 0 3 3 3 0 KAP family P-loop domain TMEM171 PF15471.1 CDO75025.1 - 0.0069 15.2 0.0 0.0077 15.0 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein family 171 RVT_2 PF07727.9 CDO75026.1 - 1.9e-82 275.9 0.0 2.5e-82 275.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hydrophobin PF01185.13 CDO75028.1 - 6e-22 77.8 11.4 7.3e-22 77.6 7.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.13 CDO75028.1 - 0.14 12.3 7.6 0.27 11.3 1.5 2.4 2 0 0 2 2 2 0 Granulin Microtub_assoc PF07989.6 CDO75029.1 - 1.4e-21 76.0 9.4 1.4e-21 76.0 6.5 10.2 6 4 3 11 11 11 3 Microtubule associated Rab5-bind PF09311.6 CDO75029.1 - 2.2e-05 24.4 38.7 2.2e-05 24.4 26.8 6.7 3 1 2 6 6 6 2 Rabaptin-like protein Reo_sigmaC PF04582.7 CDO75029.1 - 0.00027 20.2 35.1 0.2 10.8 4.3 6.3 3 1 4 7 7 7 5 Reovirus sigma C capsid protein DUF4479 PF14794.1 CDO75029.1 - 0.12 11.9 9.3 2.5 7.7 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4479) DUF1514 PF07438.6 CDO75029.1 - 0.3 11.0 2.3 1.2 9.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) AAA_13 PF13166.1 CDO75029.1 - 1.1 7.6 115.0 0.026 12.9 15.1 5.3 2 1 2 5 5 5 0 AAA domain adh_short PF00106.20 CDO75030.1 - 9.9e-20 71.1 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO75030.1 - 1.4e-12 47.9 0.0 1.7e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO75030.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 KR domain C2 PF00168.25 CDO75031.1 - 5.4e-14 51.7 0.4 7.8e-14 51.2 0.3 1.2 1 0 0 1 1 1 1 C2 domain DUF92 PF01940.11 CDO75033.1 - 1.3e-37 129.1 4.4 1.7e-37 128.7 3.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 LGT PF01790.13 CDO75033.1 - 0.016 14.1 0.2 0.019 13.9 0.2 1.3 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase DUF2613 PF11021.3 CDO75033.1 - 5.4 6.8 7.9 3.1 7.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) p450 PF00067.17 CDO75034.1 - 4e-51 173.9 0.0 1.3e-50 172.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.17 CDO75035.1 - 0.00011 21.4 0.1 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 Subtilase family DUF2857 PF11198.3 CDO75035.1 - 0.15 11.6 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Pro-kuma_activ PF09286.6 CDO75036.1 - 1.1e-37 129.2 0.1 2.3e-24 86.0 0.1 2.5 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO75036.1 - 0.00013 21.2 0.3 0.00022 20.4 0.2 1.3 1 0 0 1 1 1 1 Subtilase family X PF00739.14 CDO75036.1 - 0.81 9.5 3.7 0.52 10.2 0.8 1.9 2 0 0 2 2 2 0 Trans-activation protein X Myb_DNA-bind_4 PF13837.1 CDO75037.1 - 5.7e-10 39.2 0.1 7.2e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO75037.1 - 2.7e-07 31.1 0.0 3.4e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO75037.1 - 9.4e-06 25.4 0.2 2.6e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO75037.1 - 0.0024 17.9 0.1 0.0031 17.5 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CDO75037.1 - 0.051 13.6 1.5 0.13 12.3 1.1 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain p450 PF00067.17 CDO75038.1 - 2.2e-52 178.1 0.0 1.5e-36 125.8 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 Helitron_like_N PF14214.1 CDO75039.1 - 2.2e-50 170.9 0.0 2.6e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus p450 PF00067.17 CDO75040.1 - 2e-41 142.0 0.1 5.4e-41 140.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 CDO75041.1 - 3e-34 118.3 0.0 4.1e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75041.1 - 2.3e-14 53.0 0.0 3.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO75041.1 - 0.0003 19.8 0.0 0.00095 18.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Retrotrans_gag PF03732.12 CDO75043.1 - 1.1e-05 25.4 0.6 2.3e-05 24.3 0.4 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotrans_gag PF03732.12 CDO75044.1 - 0.00046 20.2 0.6 0.0063 16.5 0.4 2.6 2 1 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO75044.1 - 0.011 15.6 0.3 0.02 14.7 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle PSD4 PF07631.6 CDO75045.1 - 0.07 13.4 0.1 0.17 12.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) Pkinase PF00069.20 CDO75046.1 - 3.9e-07 29.4 0.1 5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CDO75046.1 - 4.1e-05 23.4 0.0 6.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CDO75046.1 - 4.2e-05 22.7 0.3 6e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CDO75046.1 - 0.00047 19.7 0.1 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 CDO75046.1 - 0.0055 16.0 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 CDO75046.1 - 0.0081 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL EcKinase PF02958.15 CDO75046.1 - 0.046 12.8 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_Tyr PF07714.12 CDO75046.1 - 0.081 11.9 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase NapB PF03892.9 CDO75048.1 - 0.069 12.8 0.5 0.15 11.7 0.4 1.6 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) CobA_CobO_BtuR PF02572.10 CDO75048.1 - 0.1 12.2 0.6 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Gastrin PF00918.12 CDO75048.1 - 2.1 9.1 5.4 6.6 7.5 0.7 2.4 2 0 0 2 2 2 0 Gastrin/cholecystokinin family TEX19 PF15553.1 CDO75048.1 - 3 7.6 8.1 10 5.9 2.1 2.6 1 1 1 2 2 2 0 Testis-expressed protein 19 DUF2363 PF10155.4 CDO75049.1 - 0.0072 16.2 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2363) Pkinase PF00069.20 CDO75050.1 - 1.2e-77 260.5 0.4 1.4e-77 260.3 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75050.1 - 1.8e-55 187.8 0.3 2.4e-55 187.4 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO75050.1 - 9.6e-09 34.5 0.0 1.7e-07 30.4 0.0 2.5 2 1 0 3 3 3 1 Kinase-like APH PF01636.18 CDO75050.1 - 1.9e-05 24.5 0.1 0.0025 17.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CDO75050.1 - 0.0053 15.6 1.8 0.0058 15.4 0.2 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Kdo PF06293.9 CDO75050.1 - 0.086 11.8 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBD PF00786.23 CDO75051.1 - 1.6e-21 76.4 0.1 6.3e-21 74.5 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 CDO75051.1 - 2.6e-07 30.8 0.3 4.7e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 PH domain DASH_Dam1 PF08653.5 CDO75052.1 - 3.4e-08 33.1 0.0 5.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 Glyco_transf_20 PF00982.16 CDO75053.1 - 9.5e-150 499.1 0.0 1.2e-149 498.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CDO75053.1 - 1.5e-24 86.1 0.0 1.6e-23 82.8 0.0 2.1 2 0 0 2 2 2 1 Trehalose-phosphatase Peptidase_M28 PF04389.12 CDO75054.1 - 0.00027 20.7 0.0 0.0003 20.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M28 PF04389.12 CDO75055.1 - 3e-30 105.2 0.0 5e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CDO75055.1 - 7.4e-07 28.8 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 CDO75055.1 - 0.001 18.3 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Nicastrin RNase_H PF00075.19 CDO75057.1 - 2.7e-14 53.6 0.0 4.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 CDO75057.1 - 2.9e-09 36.5 0.0 8.1e-08 31.8 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CDO75057.1 - 4.3e-07 29.5 0.1 9.6e-07 28.4 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CDO75057.1 - 0.0054 17.0 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PAS_4 PF08448.5 CDO75058.1 - 0.053 13.5 0.3 0.87 9.6 0.0 2.3 2 0 0 2 2 2 0 PAS fold MRI PF15325.1 CDO75058.1 - 0.58 11.1 3.0 1.1 10.3 2.1 1.6 1 1 0 1 1 1 0 Modulator of retrovirus infection RVT_1 PF00078.22 CDO75059.1 - 9.5e-14 51.2 0.0 3.1e-11 43.0 0.0 2.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO75059.1 - 9.5e-10 38.9 0.0 1.8e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 RNase H PAP2 PF01569.16 CDO75059.1 - 0.06 13.0 1.4 0.21 11.2 0.2 2.3 2 0 0 2 2 2 0 PAP2 superfamily ATP_bind_1 PF03029.12 CDO75060.1 - 1.2e-71 240.9 0.0 1.5e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 CDO75060.1 - 0.069 13.0 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDO75060.1 - 0.13 13.0 7.4 0.056 14.2 1.8 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CDO75060.1 - 0.19 11.6 0.7 1.9 8.4 0.5 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase GST_N_3 PF13417.1 CDO75061.1 - 1.2e-13 51.0 0.0 2.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO75061.1 - 6.1e-08 32.5 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO75061.1 - 0.00017 21.7 0.0 0.00059 19.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO75061.1 - 0.0099 15.7 0.3 0.02 14.7 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DDE_3 PF13358.1 CDO75062.1 - 3.3e-16 59.3 0.5 3.6e-16 59.2 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO75062.1 - 0.00039 20.5 0.0 0.00049 20.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Abhydrolase_6 PF12697.2 CDO75064.1 - 2.8e-21 76.4 5.0 3.4e-21 76.1 3.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO75064.1 - 4.3e-09 36.2 0.0 1.3e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO75064.1 - 2.9e-05 23.7 0.3 8.9e-05 22.1 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold AIF_C PF14721.1 CDO75064.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MFS_1 PF07690.11 CDO75065.1 - 1.4e-38 132.5 54.0 1.4e-38 132.5 37.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO75065.1 - 1.4e-26 92.9 21.9 1.7e-26 92.5 15.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CDO75065.1 - 1.8e-14 53.1 12.9 1.8e-14 53.1 8.9 4.3 3 2 2 5 5 5 1 Sugar (and other) transporter SUD-M PF11633.3 CDO75065.1 - 0.14 11.3 0.1 0.33 10.2 0.1 1.5 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain p450 PF00067.17 CDO75066.1 - 1.1e-54 185.6 0.0 1.6e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CDO75067.1 - 2.2e-62 211.1 0.0 1.6e-60 204.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Med7 PF05983.6 CDO75068.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 MED7 protein TFIIA PF03153.8 CDO75068.1 - 6.5 6.5 10.6 11 5.7 7.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNARE_assoc PF09335.6 CDO75073.1 - 5.7e-17 62.0 7.6 5.7e-17 62.0 5.2 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1230 PF06799.6 CDO75073.1 - 0.033 14.0 0.3 0.072 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1230) 7TMR-DISM_7TM PF07695.6 CDO75073.1 - 9.8 5.7 14.7 0.18 11.4 5.1 1.7 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF659 PF04937.10 CDO75074.1 - 3.4e-05 23.3 0.0 6.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.9 CDO75074.1 - 0.00059 19.4 0.9 0.0012 18.4 0.6 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4148 PF13663.1 CDO75075.1 - 0.29 10.9 0.2 0.29 10.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) UBN2_2 PF14227.1 CDO75077.1 - 2.1e-12 46.6 0.0 3.1e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO75077.1 - 4.3e-08 32.9 0.0 6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Sad1_UNC PF07738.8 CDO75080.1 - 1.8e-18 66.6 0.0 9.9e-17 60.9 0.0 2.0 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal HrpB7 PF09486.5 CDO75081.1 - 0.013 15.4 1.6 0.013 15.4 1.1 2.6 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Transposase_21 PF02992.9 CDO75085.1 - 5.4e-23 81.2 0.0 1e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 CDO75085.1 - 0.006 15.7 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) Prefoldin PF02996.12 CDO75085.1 - 0.074 12.7 0.1 0.074 12.7 0.1 3.1 2 1 1 3 3 3 0 Prefoldin subunit AvrE PF11725.3 CDO75085.1 - 0.091 9.7 1.8 0.14 9.1 1.3 1.2 1 0 0 1 1 1 0 Pathogenicity factor V_ATPase_I PF01496.14 CDO75085.1 - 0.35 8.6 6.8 0.54 8.0 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.4 CDO75085.1 - 0.55 10.4 4.6 0.45 10.6 0.2 2.5 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 CDO75085.1 - 0.98 9.7 6.5 9.8 6.5 1.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Prominin PF05478.6 CDO75085.1 - 1.3 6.4 1.8 1.8 5.9 1.2 1.1 1 0 0 1 1 1 0 Prominin DUF4618 PF15397.1 CDO75085.1 - 5.3 6.2 11.8 2.4 7.4 3.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DegS PF05384.6 CDO75085.1 - 7.5 5.7 11.3 0.47 9.6 0.6 2.3 1 1 1 2 2 2 0 Sensor protein DegS Dimer_Tnp_hAT PF05699.9 CDO75086.1 - 4.5e-23 80.6 0.0 9.2e-23 79.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 CDO75086.1 - 2.2e-05 24.3 0.2 7.5e-05 22.6 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DUF4218 PF13960.1 CDO75087.1 - 1.9e-09 37.0 0.1 4.7e-09 35.7 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Pkinase PF00069.20 CDO75088.1 - 9.2e-22 77.4 0.0 1.6e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 CDO75088.1 - 1.3e-21 75.6 16.6 5.4e-09 35.5 0.6 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat HEAT PF02985.17 CDO75088.1 - 2.2e-09 36.5 13.0 0.037 14.0 0.1 6.3 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.12 CDO75088.1 - 6.6e-09 35.2 0.0 1.3e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 CDO75088.1 - 1.5e-05 25.1 1.7 0.18 12.1 0.0 3.3 2 2 0 2 2 2 2 HEAT repeats Nucleoporin_N PF08801.6 CDO75088.1 - 0.0019 17.0 0.2 6.5 5.3 0.0 3.9 3 1 1 4 4 4 1 Nup133 N terminal like Cnd1 PF12717.2 CDO75088.1 - 0.074 12.9 3.3 3.5 7.4 0.2 3.0 2 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 CDO75088.1 - 0.24 11.4 5.7 3 7.8 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion UcrQ PF02939.11 CDO75090.1 - 1.5e-22 79.1 2.8 1.9e-22 78.8 1.9 1.1 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 CDO75090.1 - 0.00017 21.6 0.1 0.00022 21.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2741) HSP20 PF00011.16 CDO75091.1 - 9.2e-11 41.5 0.0 1.8e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Hsp20/alpha crystallin family TPT PF03151.11 CDO75092.1 - 8.8e-25 87.1 9.2 3e-23 82.1 0.9 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 CDO75092.1 - 9.5e-12 44.4 10.6 2.3e-11 43.2 7.3 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CDO75092.1 - 8.1e-09 35.5 26.2 2.7e-06 27.4 4.6 3.1 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CDO75092.1 - 0.00018 21.6 20.4 0.00064 19.8 2.5 2.9 3 0 0 3 3 3 2 Multidrug resistance efflux transporter Phage_HK97_TLTM PF06120.6 CDO75092.1 - 0.24 10.6 2.1 12 5.1 0.5 2.1 2 0 0 2 2 2 0 Tail length tape measure protein zf-C3HC4_2 PF13923.1 CDO75093.1 - 1.6e-07 31.2 7.9 1.6e-07 31.2 5.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO75093.1 - 3.9e-07 29.6 6.5 3.9e-07 29.6 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO75093.1 - 7.2e-07 28.7 5.9 7.2e-07 28.7 4.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO75093.1 - 2.1e-06 27.3 5.2 2.1e-06 27.3 3.6 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CDO75093.1 - 6.7e-06 25.8 8.7 6.7e-06 25.8 6.1 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 CDO75093.1 - 4.8e-05 23.1 3.8 4.8e-05 23.1 2.7 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CDO75093.1 - 0.0081 15.8 3.6 0.0081 15.8 2.5 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 CDO75093.1 - 0.14 12.0 4.2 0.069 12.9 0.9 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CDO75093.1 - 0.93 9.1 13.5 0.91 9.1 2.4 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 CDO75093.1 - 5 6.7 9.5 0.9 9.1 3.1 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Peptidase_S10 PF00450.17 CDO75095.1 - 1.2e-45 156.4 0.0 1.5e-24 86.9 1.7 2.4 1 1 1 2 2 2 2 Serine carboxypeptidase CSTF2_hinge PF14327.1 CDO75095.1 - 8.3e-23 80.2 0.8 2e-22 79.0 0.6 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 CDO75095.1 - 3.1e-10 39.5 0.0 6.1e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 CDO75095.1 - 1.9e-07 30.2 2.4 3.8e-07 29.2 1.6 1.5 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 CDO75095.1 - 1.3e-06 28.1 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO75095.1 - 1.1e-05 25.3 0.0 2.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MCM PF00493.18 CDO75096.1 - 8.6e-138 458.6 0.0 1.1e-137 458.2 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CDO75096.1 - 1.3e-21 77.3 0.0 6.7e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 CDO75096.1 - 5.2e-08 32.7 0.0 1.3e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CDO75096.1 - 2e-07 30.3 0.0 5.4e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CDO75096.1 - 0.00027 20.5 0.0 0.0038 16.8 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CDO75096.1 - 0.0018 17.7 0.0 1 8.8 0.0 2.8 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.1 CDO75096.1 - 1.4 8.8 4.8 5.8 6.8 1.0 3.5 3 1 0 3 3 3 0 AAA ATPase domain MMR_HSR1 PF01926.18 CDO75097.1 - 3e-18 65.8 0.0 7.3e-18 64.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.17 CDO75097.1 - 1.8e-08 34.1 0.0 3.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 GTP1/OBG Miro PF08477.8 CDO75097.1 - 1.9e-05 25.1 0.0 0.0013 19.1 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein cobW PF02492.14 CDO75097.1 - 1.9e-05 24.1 0.1 0.012 15.0 0.0 2.5 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 CDO75097.1 - 9.3e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.22 CDO75097.1 - 0.00012 21.5 0.0 0.00056 19.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CDO75097.1 - 0.00027 20.2 0.0 0.00096 18.4 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 CDO75097.1 - 0.00031 20.0 0.0 0.4 9.8 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family ABC_tran PF00005.22 CDO75097.1 - 0.0026 18.0 0.0 0.007 16.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ArgK PF03308.11 CDO75097.1 - 0.012 14.3 0.3 0.046 12.4 0.2 1.9 1 1 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 CDO75097.1 - 0.041 14.2 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CDO75097.1 - 0.053 14.3 0.6 0.19 12.5 0.4 2.2 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 CDO75097.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.17 CDO75097.1 - 0.17 11.2 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Ras family RNase_H PF00075.19 CDO75099.1 - 7e-14 52.3 0.0 1.5e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 CDO75099.1 - 1.2e-13 50.8 0.0 2.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CDO75099.1 - 0.00049 20.3 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Ank_2 PF12796.2 CDO75103.1 - 3.9e-25 87.9 0.0 2.1e-14 53.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CDO75103.1 - 1.2e-13 50.1 0.1 4.4e-07 29.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CDO75103.1 - 2.5e-13 49.7 0.3 6.4e-07 29.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDO75103.1 - 5e-12 45.9 0.2 1.2e-07 32.0 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO75103.1 - 9.6e-10 37.7 0.1 6.9e-06 25.8 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat zf-MYND PF01753.13 CDO75103.1 - 2.2e-07 30.6 13.9 4.5e-06 26.4 7.5 2.3 2 0 0 2 2 2 2 MYND finger SPX PF03105.14 CDO75104.1 - 4e-42 144.9 2.4 4e-42 144.9 1.6 2.1 2 0 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 CDO75104.1 - 2.7e-33 115.5 30.9 3.7e-33 115.1 21.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CDO75104.1 - 6.3e-20 71.0 26.7 2.1e-15 56.1 6.1 2.2 1 1 1 2 2 2 2 Citrate transporter DUF544 PF04424.8 CDO75104.1 - 2.3e-16 59.6 0.0 7.7e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF544) DUF3886 PF13025.1 CDO75104.1 - 1.6 8.7 14.3 5.3 7.0 9.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) SAM_2 PF07647.12 CDO75105.1 - 0.0066 16.2 0.1 0.028 14.2 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CDO75105.1 - 0.0076 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) KilA-N PF04383.8 CDO75106.1 - 0.1 12.2 0.2 0.65 9.6 0.1 2.0 1 1 0 1 1 1 0 KilA-N domain Orn_Arg_deC_N PF02784.11 CDO75107.1 - 2.4e-73 246.4 0.0 3.1e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CDO75107.1 - 1.7e-32 111.5 0.0 3e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PTPA PF03095.10 CDO75108.1 - 2.5e-91 305.9 0.0 3.2e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ku_N PF03731.10 CDO75109.1 - 4.9e-24 85.0 0.0 8.3e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 CDO75109.1 - 1.7e-18 66.7 0.0 1.2e-17 63.9 0.0 2.2 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain SAP PF02037.22 CDO75109.1 - 5.2e-10 38.5 0.0 1.4e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 CDO75109.1 - 3.2e-05 24.3 0.4 0.00055 20.4 0.0 2.5 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 CDO75109.1 - 9.8e-05 22.5 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_S22 PF08136.6 CDO75109.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 30S ribosomal protein subunit S22 family Glutaredoxin PF00462.19 CDO75110.1 - 7.1e-20 70.7 0.0 1.2e-18 66.7 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CDO75110.1 - 8.9e-17 60.6 0.0 1.5e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CDO75110.1 - 5.6e-06 26.3 0.0 0.0019 18.2 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like HyaE PF07449.6 CDO75110.1 - 1.7e-05 24.6 0.0 0.00017 21.4 0.0 2.3 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 CDO75110.1 - 0.00052 19.7 0.1 0.031 14.0 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.1 CDO75110.1 - 0.0008 19.5 0.0 0.014 15.6 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain Phosducin PF02114.11 CDO75110.1 - 0.0045 15.7 0.0 0.0074 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosducin SH3BGR PF04908.10 CDO75110.1 - 0.01 15.7 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.1 CDO75110.1 - 0.027 14.6 0.0 0.073 13.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TrbC_Ftype PF09673.5 CDO75110.1 - 0.034 13.7 0.0 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_7 PF13899.1 CDO75110.1 - 0.045 13.7 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like ADH_N PF08240.7 CDO75111.1 - 3.2e-14 52.6 0.1 6.1e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO75111.1 - 1.8e-11 43.7 0.1 2.3e-10 40.1 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO75111.1 - 2.9e-06 28.1 0.2 8.8e-06 26.6 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CDO75111.1 - 0.0015 17.6 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CDO75111.1 - 0.0052 16.3 0.1 0.0082 15.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain MVP_shoulder PF11978.3 CDO75111.1 - 0.11 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Shoulder domain ADH_N PF08240.7 CDO75112.1 - 2.5e-16 59.3 0.1 6.1e-16 58.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO75112.1 - 3.7e-13 49.1 0.1 1.1e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO75112.1 - 2.9e-07 31.4 0.2 6.9e-07 30.2 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CDO75112.1 - 0.00048 19.3 0.0 0.00082 18.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CDO75112.1 - 0.0021 17.6 0.1 0.0035 16.9 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 CDO75112.1 - 0.49 10.2 2.1 1.7 8.4 0.4 2.4 1 1 1 2 2 2 0 ThiF family Maf PF02545.9 CDO75113.1 - 2.8e-39 134.2 0.0 8.9e-16 57.5 0.0 3.0 3 0 0 3 3 3 3 Maf-like protein DUF1117 PF06547.7 CDO75114.1 - 0.39 10.8 4.0 0.53 10.3 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) DUF566 PF04484.7 CDO75114.1 - 1.6 8.1 7.1 1.8 7.9 4.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) Aminotran_1_2 PF00155.16 CDO75115.1 - 7.1e-17 61.4 0.0 9.9e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RNase_P_Rpp14 PF01900.14 CDO75116.1 - 1.3e-28 98.9 0.0 1.6e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family RabGAP-TBC PF00566.13 CDO75118.1 - 2.3e-49 167.7 0.0 3.9e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3927 PF13064.1 CDO75119.1 - 0.038 13.4 0.6 0.094 12.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) AAA PF00004.24 CDO75120.1 - 2.5e-94 312.4 0.0 2.8e-47 160.2 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDO75120.1 - 2.8e-15 56.0 0.0 2.7e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CDO75120.1 - 5.6e-12 45.9 0.4 0.0048 17.0 0.0 4.9 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 CDO75120.1 - 1.9e-11 44.2 5.1 0.00012 22.1 0.0 4.2 3 2 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 CDO75120.1 - 9.2e-11 42.6 0.0 1.1e-05 26.2 0.0 2.8 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CDO75120.1 - 2.1e-10 40.6 0.0 0.00012 22.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CDO75120.1 - 2.7e-10 40.1 0.6 0.0017 18.0 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CDO75120.1 - 5.2e-10 39.4 0.0 0.00055 19.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CDO75120.1 - 2.1e-09 37.3 0.0 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CDO75120.1 - 3.5e-09 35.8 0.0 5.5e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 CDO75120.1 - 1.4e-08 34.3 1.9 0.0018 17.9 0.1 4.0 3 1 0 3 3 2 2 Part of AAA domain Zeta_toxin PF06414.7 CDO75120.1 - 1.7e-08 33.8 0.0 0.0034 16.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 CDO75120.1 - 3.9e-08 33.4 0.0 0.0097 16.0 0.0 2.8 2 1 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 CDO75120.1 - 9.5e-08 31.6 4.2 0.35 10.2 0.0 4.5 2 2 2 4 4 4 2 AAA domain IstB_IS21 PF01695.12 CDO75120.1 - 1.2e-07 31.3 0.0 0.016 14.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 CDO75120.1 - 2.5e-07 30.4 0.5 0.041 13.5 0.0 4.0 3 1 1 4 4 4 2 NACHT domain Mg_chelatase PF01078.16 CDO75120.1 - 2.9e-07 29.8 0.3 0.016 14.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CDO75120.1 - 1.2e-06 28.5 0.0 0.04 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 CDO75120.1 - 3e-06 26.8 0.0 0.0074 15.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CDO75120.1 - 6.6e-06 26.4 0.0 0.066 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CDO75120.1 - 1e-05 25.8 0.0 0.22 11.8 0.0 3.0 3 1 0 3 3 2 2 ABC transporter KaiC PF06745.8 CDO75120.1 - 2.1e-05 23.7 0.3 0.95 8.5 0.0 3.6 3 1 0 4 4 4 2 KaiC Sigma54_activ_2 PF14532.1 CDO75120.1 - 7.5e-05 22.7 0.0 0.55 10.2 0.0 3.1 3 0 0 3 3 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 CDO75120.1 - 9.3e-05 21.9 0.0 0.5 9.8 0.0 3.4 3 0 0 3 3 3 2 Sigma-54 interaction domain SKI PF01202.17 CDO75120.1 - 0.00012 22.0 0.0 0.86 9.4 0.0 3.0 3 0 0 3 3 3 2 Shikimate kinase DUF815 PF05673.8 CDO75120.1 - 0.00016 20.7 0.0 0.018 13.9 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Cytidylate_kin2 PF13189.1 CDO75120.1 - 0.00022 21.1 0.0 0.057 13.3 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family NB-ARC PF00931.17 CDO75120.1 - 0.00023 20.1 0.0 0.4 9.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.13 CDO75120.1 - 0.00046 19.7 0.0 0.56 9.6 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 CDO75120.1 - 0.00088 18.5 0.5 1.2 8.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Rad17 PF03215.10 CDO75120.1 - 0.0011 17.7 0.0 0.31 9.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Vps4_C PF09336.5 CDO75120.1 - 0.0012 18.7 0.0 0.21 11.5 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Arch_ATPase PF01637.13 CDO75120.1 - 0.0012 18.5 0.0 2.5 7.7 0.0 3.2 2 1 1 3 3 3 1 Archaeal ATPase ATP-synt_ab PF00006.20 CDO75120.1 - 0.0013 18.3 0.0 0.45 9.9 0.0 3.0 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 CDO75120.1 - 0.0016 18.0 0.1 0.62 9.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 CDO75120.1 - 0.0021 16.9 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 CDO75120.1 - 0.0026 17.4 0.0 4.4 6.8 0.0 3.1 2 1 0 2 2 2 0 Bacterial dnaA protein NTPase_1 PF03266.10 CDO75120.1 - 0.0049 16.6 0.0 2.1 8.0 0.0 2.9 2 1 1 3 3 2 1 NTPase AAA_11 PF13086.1 CDO75120.1 - 0.0065 16.0 0.0 2.7 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CDO75120.1 - 0.018 14.6 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 CDO75120.1 - 0.031 13.2 0.0 3.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 CDO75120.1 - 0.059 12.9 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.4 CDO75120.1 - 0.065 12.7 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 CDO75120.1 - 0.067 13.0 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.11 CDO75120.1 - 0.1 11.4 0.0 3.5 6.3 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase DAP3 PF10236.4 CDO75120.1 - 0.19 10.6 0.0 2.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Abhydrolase_6 PF12697.2 CDO75121.1 - 6.7e-27 94.8 0.1 1.1e-26 94.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO75121.1 - 3.6e-09 36.5 0.0 1.1e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO75121.1 - 2.3e-08 33.8 0.0 1.2e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CDO75121.1 - 8.3e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CDO75121.1 - 8.4e-06 26.1 0.0 1.9e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain DUF2305 PF10230.4 CDO75121.1 - 0.019 14.4 0.0 0.04 13.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 CDO75121.1 - 0.035 13.5 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 CDO75121.1 - 0.044 13.3 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 CDO75121.1 - 0.095 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) TPR_11 PF13414.1 CDO75122.1 - 1e-16 60.3 6.1 1.9e-13 49.8 1.8 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CDO75122.1 - 6.1e-13 47.6 5.1 0.0004 20.0 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDO75122.1 - 1.4e-11 43.4 5.8 0.0054 16.2 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CDO75122.1 - 3.6e-11 43.2 2.7 5.6e-09 36.2 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDO75122.1 - 3.6e-08 33.8 10.9 6.8e-06 26.6 0.2 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDO75122.1 - 0.00019 21.3 8.5 0.24 11.3 1.0 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO75122.1 - 0.00033 21.0 16.0 0.0022 18.4 1.4 4.4 5 1 1 6 6 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 CDO75122.1 - 0.00089 18.3 0.6 0.0019 17.3 0.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO75122.1 - 0.004 16.8 0.7 7 6.6 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO75122.1 - 0.0052 16.4 3.8 0.83 9.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Phage_P2_GpE PF06528.7 CDO75122.1 - 0.019 14.3 0.2 0.062 12.7 0.1 1.8 1 0 0 1 1 1 0 Phage P2 GpE Fis1_TPR_C PF14853.1 CDO75122.1 - 0.047 13.5 3.1 3 7.8 0.1 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 CDO75122.1 - 0.15 11.8 5.7 0.097 12.5 1.2 2.5 2 1 1 3 3 2 0 Tetratricopeptide repeat BTAD PF03704.12 CDO75122.1 - 0.16 12.2 3.8 3.2 8.0 2.7 2.9 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 CDO75122.1 - 0.28 11.7 8.9 1.5 9.4 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CDO75122.1 - 0.57 10.5 3.3 19 5.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat HemY_N PF07219.8 CDO75122.1 - 0.58 9.7 2.7 11 5.6 0.1 2.4 2 0 0 2 2 2 0 HemY protein N-terminus Chorion_2 PF03964.10 CDO75122.1 - 3.7 8.1 12.6 0.65 10.5 1.1 2.6 2 0 0 2 2 2 0 Chorion family 2 Zip PF02535.17 CDO75122.1 - 3.9 6.3 6.0 6 5.7 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Metal_resist PF13801.1 CDO75122.1 - 5.3 7.0 8.2 0.73 9.8 1.2 2.7 3 0 0 3 3 3 0 Heavy-metal resistance MFS_1 PF07690.11 CDO75123.1 - 6.3e-26 90.9 44.0 9.1e-26 90.3 30.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO75123.1 - 1.4e-13 50.2 12.0 1.4e-13 50.2 8.3 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CDO75123.1 - 4.7e-06 25.1 9.3 4.7e-06 25.1 6.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Arrestin_N PF00339.24 CDO75124.1 - 7.4e-06 25.8 0.0 2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CDO75124.1 - 0.011 15.8 0.0 0.074 13.1 0.0 2.5 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain FmdA_AmdA PF03069.10 CDO75125.1 - 7.5e-120 399.9 0.0 9.9e-120 399.5 0.0 1.2 1 0 0 1 1 1 1 Acetamidase/Formamidase family Aldedh PF00171.17 CDO75126.1 - 2.6e-61 207.4 0.0 1.4e-35 122.5 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Phage-scaffold PF09306.5 CDO75126.1 - 0.076 12.1 0.1 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacteriophage, scaffolding protein Med9 PF07544.8 CDO75127.1 - 0.0011 18.6 0.7 1.7 8.4 0.1 2.6 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 zf-C4H2 PF10146.4 CDO75127.1 - 0.42 10.6 3.4 0.32 10.9 0.7 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein DUF4472 PF14739.1 CDO75127.1 - 0.69 10.3 4.3 0.62 10.5 0.2 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4472) MBOAT PF03062.14 CDO75129.1 - 7.8e-15 54.7 6.4 7.8e-15 54.7 4.4 2.8 4 0 0 4 4 4 1 MBOAT, membrane-bound O-acyltransferase family ESSS PF10183.4 CDO75129.1 - 0.11 12.9 2.4 3.3 8.1 0.0 3.0 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CK_II_beta PF01214.13 CDO75130.1 - 4.3e-50 169.7 0.0 5.1e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4139 PF13598.1 CDO75131.1 - 1.8e-67 227.9 4.3 9.1e-67 225.6 3.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 CDO75131.1 - 2.4e-12 47.1 4.7 6.1e-09 36.2 0.2 2.7 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) DivIVA PF05103.8 CDO75131.1 - 0.0037 17.3 1.6 0.0082 16.1 1.1 1.5 1 0 0 1 1 1 1 DivIVA protein Apc9 PF12856.2 CDO75131.1 - 0.065 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 Corona_nucleoca PF00937.13 CDO75131.1 - 1.1 8.1 4.3 0.49 9.2 0.8 1.9 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF4139 PF13598.1 CDO75132.1 - 5.9e-60 203.2 2.8 2.9e-42 145.1 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 CDO75132.1 - 0.00071 19.9 7.1 0.19 12.1 0.8 2.9 1 1 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) DivIVA PF05103.8 CDO75132.1 - 0.016 15.2 0.1 0.016 15.2 0.1 1.9 3 0 0 3 3 3 0 DivIVA protein HalX PF08663.5 CDO75132.1 - 0.72 9.8 4.6 1.6 8.7 0.4 2.6 2 0 0 2 2 2 0 HalX domain DivIC PF04977.10 CDO75132.1 - 0.72 9.3 2.4 1.3 8.5 0.2 2.1 2 0 0 2 2 2 0 Septum formation initiator Abhydrolase_6 PF12697.2 CDO75137.1 - 2e-22 80.2 0.9 2.3e-22 79.9 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO75137.1 - 5.7e-08 32.6 0.0 1.1e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO75137.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 CDO75138.1 - 2.9e-38 131.4 56.7 2.6e-36 125.0 39.3 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO75138.1 - 1.3e-18 66.6 25.2 3.8e-17 61.7 17.4 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CDO75138.1 - 1.3e-13 50.3 11.9 1.3e-13 50.3 8.2 3.5 3 1 1 4 4 4 2 Sugar (and other) transporter RVT_2 PF07727.9 CDO75139.1 - 1.3e-94 315.7 0.0 4.4e-94 314.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO75139.1 - 8.9e-26 90.3 0.1 7.4e-24 84.1 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain UBN2_2 PF14227.1 CDO75139.1 - 5.7e-13 48.4 0.4 2.7e-12 46.2 0.6 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO75139.1 - 1.1e-11 44.2 0.3 5.7e-11 41.8 0.0 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain UBN2 PF14223.1 CDO75139.1 - 2.1e-10 40.4 0.1 7.9e-09 35.3 0.1 2.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 CDO75139.1 - 8.2e-05 22.0 0.0 0.00029 20.3 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain UBN2_3 PF14244.1 CDO75139.1 - 0.0048 16.4 0.0 0.013 15.0 0.0 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type ATG16 PF08614.6 CDO75139.1 - 0.055 13.2 0.8 0.11 12.3 0.6 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-CCHC PF00098.18 CDO75139.1 - 0.51 10.3 5.8 1.2 9.2 4.0 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF3184 PF11380.3 CDO75140.1 - 0.0013 16.7 2.4 0.0045 15.0 1.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3184) DNA_pol_A_exo1 PF01612.15 CDO75141.1 - 5.5e-37 126.9 0.0 9.8e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CDO75141.1 - 3.1e-17 62.6 0.1 2.1e-16 59.9 0.0 2.1 2 0 0 2 2 2 1 PMC2NT (NUC016) domain TPR_11 PF13414.1 CDO75142.1 - 3.3e-22 77.8 1.5 3.3e-17 61.8 0.2 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CDO75142.1 - 2.1e-16 58.7 3.5 1.3e-05 24.6 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.1 CDO75142.1 - 2.2e-16 59.5 0.0 8.5e-16 57.7 0.0 1.9 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.12 CDO75142.1 - 3.1e-13 48.5 6.2 0.00039 20.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDO75142.1 - 6.4e-11 42.6 11.6 2e-06 28.3 0.2 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CDO75142.1 - 2e-07 31.2 2.8 6.1e-06 26.4 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CDO75142.1 - 2.2e-05 24.2 5.2 5.5e-05 22.9 3.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDO75142.1 - 7.4e-05 22.6 0.8 0.2 11.9 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO75142.1 - 8.3e-05 22.8 8.2 0.042 14.4 0.2 3.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO75142.1 - 0.0019 17.8 1.5 4.5 7.3 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDO75142.1 - 0.034 14.0 2.1 0.82 9.6 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 CDO75142.1 - 0.05 13.4 0.9 7.6 6.5 0.0 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 CDO75142.1 - 0.068 12.2 3.2 0.63 9.0 2.2 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 CDO75142.1 - 0.12 12.2 2.5 1 9.3 1.1 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF4398 PF14346.1 CDO75142.1 - 8.9 6.4 9.7 0.28 11.2 1.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) UBN2_2 PF14227.1 CDO75143.1 - 5.3e-19 67.9 0.0 9.6e-19 67.1 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO75143.1 - 2e-18 66.3 0.0 2.7e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO75143.1 - 9.3e-12 44.7 0.0 1.2e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 CDO75143.1 - 0.0027 17.7 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1759 PF03564.10 CDO75143.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF4219 PF13961.1 CDO75143.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.1 CDO75144.1 - 2.2e-09 36.8 0.0 4.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 CDO75144.1 - 1.1e-08 35.1 0.0 2.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 CDO75144.1 - 0.034 14.0 0.8 0.069 13.1 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle UBN2_3 PF14244.1 CDO75145.1 - 0.0038 16.7 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF605 PF04652.11 CDO75146.1 - 0.68 9.2 9.8 0.75 9.1 6.8 1.1 1 0 0 1 1 1 0 Vta1 like Bac_rhodopsin PF01036.13 CDO75147.1 - 1.5e-36 125.8 25.5 2.2e-36 125.2 17.7 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4231 PF14015.1 CDO75147.1 - 0.44 10.5 14.4 1.6 8.7 1.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Ferric_reduct PF01794.14 CDO75148.1 - 3.9e-18 65.7 6.4 3.9e-18 65.7 4.4 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CDO75148.1 - 2.9e-11 43.1 0.0 4.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CDO75148.1 - 6.7e-11 42.3 0.0 3.5e-10 39.9 0.0 2.2 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ctr PF04145.10 CDO75149.1 - 1.6e-28 99.5 0.2 2.3e-28 99.0 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Aldo_ket_red PF00248.16 CDO75151.1 - 7.2e-22 77.5 0.0 1.3e-21 76.6 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Cupin_8 PF13621.1 CDO75153.1 - 1.5e-59 201.5 0.0 2.1e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CDO75153.1 - 0.00097 18.4 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Nop14 PF04147.7 CDO75153.1 - 4.6 5.0 14.9 6.9 4.4 10.4 1.2 1 0 0 1 1 1 0 Nop14-like family IncA PF04156.9 CDO75154.1 - 4.7e-05 23.0 0.2 6.1e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 IncA protein Lebercilin PF15619.1 CDO75154.1 - 0.013 14.9 2.9 0.019 14.3 2.0 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Tmemb_cc2 PF10267.4 CDO75154.1 - 0.02 13.4 0.4 0.031 12.8 0.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Peptidase_S64 PF08192.6 CDO75154.1 - 0.029 12.7 1.7 0.036 12.4 1.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Seryl_tRNA_N PF02403.17 CDO75154.1 - 0.12 12.4 1.4 0.19 11.7 1.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EzrA PF06160.7 CDO75154.1 - 0.12 10.5 2.3 0.17 10.0 1.6 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3808 PF10300.4 CDO75156.1 - 2.7e-67 227.3 1.0 9e-43 146.5 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3808) Glyco_hydro_38 PF01074.17 CDO75156.1 - 2.4e-64 217.2 0.0 1.6e-56 191.6 0.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CDO75156.1 - 2.5e-49 168.3 0.0 3.5e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain TPR_8 PF13181.1 CDO75156.1 - 0.0032 17.1 3.9 0.45 10.4 0.4 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CDO75156.1 - 0.004 16.7 8.4 0.11 12.1 0.6 4.1 3 2 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 CDO75156.1 - 0.99 9.1 5.5 7.2 6.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CDO75156.1 - 2.9 7.8 17.9 10 6.1 1.9 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDO75156.1 - 4.4 7.9 7.1 2.7 8.6 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TEA PF01285.13 CDO75157.1 - 2.6e-12 46.6 0.1 4.4e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain family SLAC1 PF03595.12 CDO75158.1 - 1.6e-46 158.4 47.7 2.4e-46 157.9 33.1 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel IBR PF01485.16 CDO75159.1 - 6.1e-07 29.2 36.2 2.6e-05 23.9 4.5 3.6 3 1 0 3 3 3 2 IBR domain DUF2835 PF11197.3 CDO75159.1 - 0.23 11.2 0.0 0.44 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) RRM_1 PF00076.17 CDO75163.1 - 2e-15 56.1 0.0 5.2e-15 54.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO75163.1 - 5.7e-12 45.4 0.0 1.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO75163.1 - 4.6e-09 35.9 0.0 8.6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.8 CDO75163.1 - 1.8 8.3 25.9 0.99 9.2 16.3 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPR_2 PF07719.12 CDO75164.1 - 2.2e-26 89.5 4.8 0.00045 19.9 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 CDO75164.1 - 4.3e-21 74.3 6.1 0.00035 20.1 0.0 6.6 7 0 0 7 7 7 4 TPR repeat TPR_1 PF00515.23 CDO75164.1 - 8.7e-21 72.6 1.8 0.0005 19.5 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 CDO75164.1 - 1.6e-19 69.8 2.5 8.8e-08 32.1 0.0 5.3 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CDO75164.1 - 1.6e-18 66.4 2.2 6.9e-10 38.7 0.0 7.1 5 2 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDO75164.1 - 6.2e-14 52.2 12.0 2e-05 25.0 0.0 7.4 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 CDO75164.1 - 4.4e-12 44.8 0.3 0.0004 19.9 0.0 6.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO75164.1 - 3.1e-11 43.4 1.3 0.0068 16.7 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDO75164.1 - 7.2e-09 35.1 0.1 5.1 7.5 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDO75164.1 - 6.9e-07 28.6 9.7 0.17 11.7 0.1 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 CDO75164.1 - 1e-06 28.4 5.9 0.00062 19.6 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDO75164.1 - 1.2e-05 25.4 8.1 0.44 11.3 0.0 7.0 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.9 CDO75164.1 - 0.00032 20.8 3.3 2.2 8.9 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDO75164.1 - 0.0052 17.1 14.8 1.7 9.2 0.0 6.6 8 0 0 8 8 8 2 Tetratricopeptide repeat Coatomer_E PF04733.9 CDO75164.1 - 0.026 13.7 0.6 3.3 6.8 0.1 3.1 2 1 1 3 3 3 0 Coatomer epsilon subunit PhnG PF06754.7 CDO75165.1 - 0.0028 17.2 0.7 0.27 10.8 0.0 2.1 2 0 0 2 2 2 2 Phosphonate metabolism protein PhnG Maf1 PF09174.5 CDO75166.1 - 3.8e-36 124.6 6.6 5.6e-31 107.7 0.6 2.4 2 1 0 2 2 2 2 Maf1 regulator B12D PF06522.6 CDO75167.1 - 0.47 10.1 3.8 0.97 9.1 2.4 1.7 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Sugar_tr PF00083.19 CDO75168.1 - 4.1e-34 117.9 20.9 1.3e-32 113.0 14.5 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO75168.1 - 2.4e-15 56.0 23.7 2.4e-15 56.0 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SCP2 PF02036.12 CDO75169.1 - 4.5e-24 84.6 0.8 5.8e-24 84.3 0.6 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CDO75169.1 - 0.00025 21.0 0.4 0.00038 20.4 0.2 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Rep_fac_C PF08542.6 CDO75169.1 - 0.049 13.6 0.1 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain DHDPS PF00701.17 CDO75170.1 - 1.3e-41 142.1 0.0 1.7e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family IstB_IS21_ATP PF08483.6 CDO75170.1 - 0.21 11.2 0.4 0.53 10.0 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal Dynamin_N PF00350.18 CDO75171.1 - 4.5e-43 146.9 0.0 8.6e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 CDO75171.1 - 2.9e-12 45.9 0.1 1.6e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region 4HBT_2 PF13279.1 CDO75171.1 - 3.8e-06 27.3 0.0 6.9e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 Thioesterase-like superfamily MMR_HSR1 PF01926.18 CDO75171.1 - 0.0011 18.9 0.0 0.003 17.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CDO75171.1 - 0.0071 16.8 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 CDO75171.1 - 0.018 15.0 2.9 1.3 8.9 0.1 3.1 2 1 1 3 3 3 0 AAA ATPase domain AAA_21 PF13304.1 CDO75171.1 - 0.18 11.7 0.2 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain Na_Ca_ex PF01699.19 CDO75173.1 - 7.5e-47 158.4 27.7 1.9e-26 92.3 5.4 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4381 PF14316.1 CDO75173.1 - 0.51 10.4 2.0 12 6.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF1469 PF07332.6 CDO75173.1 - 4 7.1 28.5 0.47 10.1 0.3 5.0 4 1 0 4 4 4 0 Protein of unknown function (DUF1469) Abhydrolase_6 PF12697.2 CDO75174.1 - 4.7e-30 105.1 0.3 5.7e-30 104.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO75174.1 - 2e-16 60.0 0.1 3.5e-16 59.2 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO75174.1 - 3.2e-10 39.9 0.1 1.7e-05 24.4 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CDO75174.1 - 4.4e-06 26.4 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CDO75174.1 - 0.0013 17.9 0.7 0.31 10.2 0.0 2.3 2 1 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 CDO75174.1 - 0.0064 15.8 0.0 0.03 13.5 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family FH2 PF02181.18 CDO75175.1 - 0.0036 16.2 0.1 0.048 12.5 0.0 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Creb_binding PF09030.5 CDO75175.1 - 0.038 14.1 0.9 0.092 12.9 0.6 1.6 1 0 0 1 1 1 0 Creb binding IncA PF04156.9 CDO75175.1 - 0.057 13.0 3.6 1.4 8.4 0.8 2.8 2 2 0 2 2 2 0 IncA protein CDC37_N PF03234.9 CDO75175.1 - 0.38 11.0 3.3 6.1 7.1 0.1 2.5 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding DUF1319 PF07028.6 CDO75175.1 - 0.55 10.4 3.5 2.5 8.2 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1319) Lebercilin PF15619.1 CDO75175.1 - 6 6.2 13.3 0.56 9.6 0.9 2.6 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease GMC_oxred_N PF00732.14 CDO75176.1 - 3.3e-64 216.8 0.0 4e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CDO75176.1 - 1e-05 24.6 0.0 0.00019 20.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDO75176.1 - 2e-05 23.6 0.0 0.011 14.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 CDO75176.1 - 2.2e-05 23.5 0.0 3.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CDO75176.1 - 0.0005 20.0 0.0 0.0057 16.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO75176.1 - 0.00066 19.6 0.1 0.0015 18.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CDO75176.1 - 0.0078 14.7 0.0 0.011 14.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 CDO75176.1 - 0.0087 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GDI PF00996.13 CDO75176.1 - 0.079 11.2 0.0 0.14 10.4 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor eIF3_subunit PF08597.5 CDO75177.1 - 1.4e-49 168.8 17.6 1.7e-49 168.6 12.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF2935 PF11155.3 CDO75177.1 - 0.032 14.3 0.0 0.059 13.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) WD40 PF00400.27 CDO75178.1 - 2.4e-24 84.2 9.7 9e-07 28.5 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 CDO75178.1 - 0.092 10.8 7.2 0.84 7.6 0.0 3.3 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Glyco_hydro_10 PF00331.15 CDO75179.1 - 4.6e-68 229.5 0.0 5e-39 134.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 CBM_1 PF00734.13 CDO75179.1 - 1.1e-13 50.5 8.9 3.1e-13 49.1 6.2 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain adh_short PF00106.20 CDO75180.1 - 1.8e-10 41.0 1.1 2.7e-10 40.4 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO75180.1 - 8.1e-06 25.7 0.0 9.9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.10 CDO75180.1 - 0.0075 15.8 0.1 0.059 12.9 0.0 2.1 2 0 0 2 2 2 1 YjeF-related protein N-terminus 3HCDH_N PF02737.13 CDO75180.1 - 0.015 14.9 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CDO75180.1 - 0.019 15.0 0.0 0.051 13.6 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HEM4 PF02602.10 CDO75180.1 - 0.082 12.1 0.1 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Glyco_hydro_10 PF00331.15 CDO75181.1 - 2.1e-39 135.4 0.0 2.3e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_10 PF00331.15 CDO75182.1 - 8.2e-59 199.2 0.0 1e-58 198.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 CDO75182.1 - 4.8e-15 54.9 8.4 1.6e-14 53.2 5.8 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase PF00150.13 CDO75182.1 - 0.036 13.2 0.1 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) E1-E2_ATPase PF00122.15 CDO75183.1 - 3.8e-59 199.4 0.5 3.8e-59 199.4 0.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CDO75183.1 - 5.5e-46 156.3 3.2 5.5e-46 156.3 2.2 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CDO75183.1 - 1.3e-25 91.0 0.0 3.2e-25 89.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDO75183.1 - 6.2e-19 67.7 0.0 1.5e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CDO75183.1 - 7.7e-14 52.2 0.1 2.6e-13 50.5 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CDO75183.1 - 1.7e-07 30.6 0.2 4.8e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CDO75183.1 - 0.00019 21.1 1.7 0.0049 16.4 0.1 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4581 PF15167.1 CDO75183.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) PEX11 PF05648.9 CDO75184.1 - 2.4e-07 30.2 0.4 5.3e-05 22.6 0.3 2.0 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) ATG22 PF11700.3 CDO75187.1 - 8e-114 380.7 23.8 9.6e-114 380.4 16.5 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Mitofilin PF09731.4 CDO75188.1 - 1.1e-114 384.2 12.6 1.3e-114 384.0 8.7 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Phage_X PF05155.10 CDO75188.1 - 0.094 12.6 0.1 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 Phage X family GBP_C PF02841.9 CDO75188.1 - 0.099 11.8 19.6 0.056 12.6 9.0 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain OmpH PF03938.9 CDO75188.1 - 2.6 7.9 17.8 0.24 11.3 7.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DNA_primase_lrg PF04104.9 CDO75188.1 - 6.1 6.0 8.2 1.8 7.7 0.3 2.3 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit USP8_interact PF08941.5 CDO75189.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 USP8 interacting ABC_membrane PF00664.18 CDO75190.1 - 5e-35 121.2 16.1 4.4e-24 85.3 1.5 3.3 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 CDO75190.1 - 9.6e-07 29.1 0.0 2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Trehalase PF01204.13 CDO75191.1 - 5.6e-154 513.5 0.1 7e-154 513.2 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CDO75191.1 - 7.3e-12 44.3 0.0 1.2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Lipase_3 PF01764.20 CDO75192.1 - 5e-08 32.6 0.0 8.5e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CDO75192.1 - 0.01 15.5 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family RVT_1 PF00078.22 CDO75194.1 - 3.6e-28 98.4 0.0 5.8e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO75194.1 - 2.2e-13 50.7 0.0 3.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO75194.1 - 0.063 13.6 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase TB2_DP1_HVA22 PF03134.14 CDO75195.1 - 2.8e-09 36.6 1.9 5.6e-09 35.6 1.3 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family G10 PF01125.12 CDO75196.1 - 6.3e-66 220.3 5.4 7e-66 220.2 3.7 1.0 1 0 0 1 1 1 1 G10 protein MFS_1 PF07690.11 CDO75197.1 - 1.2e-36 126.2 29.7 1.2e-36 126.2 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO75197.1 - 2.5e-14 52.7 24.9 5.5e-14 51.5 17.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 CDO75197.1 - 6.1e-06 24.7 0.8 9.7e-06 24.0 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 CDO75197.1 - 1.4 6.8 6.4 7.6 4.4 3.0 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.17 CDO75198.1 - 2.7e-63 214.1 0.0 3.5e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BTP PF05232.7 CDO75198.1 - 0.61 9.8 4.0 0.33 10.7 0.6 2.1 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family WD40 PF00400.27 CDO75199.1 - 1e-44 148.8 17.6 1.8e-12 46.6 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 CDO75199.1 - 8e-14 51.0 0.4 2.5e-13 49.5 0.3 1.9 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CDO75199.1 - 7.2e-06 24.4 6.9 0.21 9.6 0.1 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 F-box PF00646.28 CDO75199.1 - 0.0001 21.8 0.3 0.00024 20.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain SWIM PF04434.12 CDO75199.1 - 0.13 11.8 1.0 0.25 10.8 0.1 1.9 2 0 0 2 2 2 0 SWIM zinc finger p450 PF00067.17 CDO75200.1 - 1.5e-29 102.8 0.0 1.9e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.22 CDO75201.1 - 0.003 16.9 0.1 0.0065 15.8 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 CDO75201.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like p450 PF00067.17 CDO75203.1 - 5.3e-11 41.7 0.0 3.2e-06 25.9 0.0 3.9 3 1 1 4 4 4 4 Cytochrome P450 Mem_trans PF03547.13 CDO75204.1 - 1.7e-39 135.1 2.5 2.2e-39 134.8 1.7 1.1 1 0 0 1 1 1 1 Membrane transport protein Peptidase_M49 PF03571.10 CDO75205.1 - 2.3e-180 600.3 0.0 2.8e-180 600.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 TauD PF02668.11 CDO75206.1 - 1.5e-47 162.4 0.1 2.2e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family His_Phos_2 PF00328.17 CDO75209.1 - 2.1e-27 96.3 0.0 2.5e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2300 PF10062.4 CDO75209.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) Pyr_redox_3 PF13738.1 CDO75211.1 - 7.6e-20 71.8 0.0 2.6e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CDO75211.1 - 1.3e-12 47.3 0.0 1.2e-09 37.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 CDO75211.1 - 8e-12 44.1 0.0 1.2e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 CDO75211.1 - 7.9e-09 35.6 0.0 0.00065 19.6 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CDO75211.1 - 2.5e-07 29.9 1.0 0.0026 16.7 0.2 3.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CDO75211.1 - 1e-06 29.0 0.4 0.0014 18.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO75211.1 - 4.3e-06 26.6 2.7 0.0001 22.2 0.1 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CDO75211.1 - 7.2e-06 25.8 0.1 0.068 12.9 0.0 3.6 2 2 0 2 2 2 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 CDO75211.1 - 0.00018 21.5 0.1 0.86 9.7 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 CDO75211.1 - 0.0003 19.7 0.5 0.13 11.0 0.0 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 CDO75211.1 - 0.0011 18.0 0.0 0.069 12.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 CDO75211.1 - 0.0029 17.8 0.0 0.076 13.2 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 CDO75211.1 - 0.0055 15.5 4.0 0.021 13.7 0.2 2.7 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 CDO75211.1 - 0.0064 15.0 0.9 2.9 6.2 0.1 3.7 4 0 0 4 4 4 1 HI0933-like protein 3HCDH_N PF02737.13 CDO75211.1 - 0.14 11.8 0.1 20 4.7 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CDO75211.1 - 0.24 11.0 0.3 16 5.2 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4419 PF14388.1 CDO75212.1 - 6.1e-27 94.6 0.0 8e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Ubiq_cyt_C_chap PF03981.7 CDO75213.1 - 1.2e-27 96.5 0.1 5.7e-14 52.1 0.0 3.0 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Cpn60_TCP1 PF00118.19 CDO75214.1 - 3.6e-117 391.9 8.1 4.2e-117 391.7 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Paramyx_P_V_C PF03210.8 CDO75214.1 - 0.049 13.5 0.1 2.5 7.9 0.0 2.8 2 1 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal FIST PF08495.5 CDO75214.1 - 0.055 12.6 1.5 5.3 6.1 0.1 2.9 2 1 0 2 2 2 0 FIST N domain polyprenyl_synt PF00348.12 CDO75215.1 - 6.6e-33 113.6 0.0 8.1e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase DUF2795 PF11387.3 CDO75215.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) Epimerase PF01370.16 CDO75217.1 - 5.8e-22 78.2 0.0 2.6e-21 76.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO75217.1 - 8.2e-15 54.2 0.0 1.3e-14 53.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CDO75217.1 - 6.2e-14 52.4 0.7 4e-13 49.7 0.5 2.2 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CDO75217.1 - 3.7e-11 42.4 0.0 9.5e-11 41.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 CDO75217.1 - 3.9e-06 25.9 0.0 5.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CDO75217.1 - 2.6e-05 24.2 0.4 6e-05 23.0 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO75217.1 - 0.00039 20.1 0.7 0.001 18.8 0.5 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO75218.1 - 0.037 13.4 0.1 0.085 12.2 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family YWFCY PF14293.1 CDO75219.1 - 1.1 9.1 8.0 3.3 7.6 0.8 2.3 2 0 0 2 2 2 0 YWFCY protein Chromo PF00385.19 CDO75221.1 - 3e-09 36.4 0.0 5.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CDO75221.1 - 0.025 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromo shadow domain RVT_1 PF00078.22 CDO75222.1 - 1.4e-24 86.6 0.0 2.5e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO75222.1 - 2.5e-12 46.9 0.0 5.8e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.6 CDO75222.1 - 2.1e-08 34.2 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CDO75222.1 - 1.9e-07 31.4 0.0 4.7e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO75222.1 - 9.8e-06 25.3 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 CDO75223.1 - 0.011 15.7 2.1 0.011 15.7 1.5 2.5 1 1 1 2 2 2 0 Retrotransposon gag protein PNMA PF14893.1 CDO75223.1 - 0.053 12.5 0.9 0.082 11.9 0.6 1.3 1 1 0 1 1 1 0 PNMA OTCace PF00185.19 CDO75223.1 - 0.068 13.0 0.1 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain UBN2_3 PF14244.1 CDO75223.1 - 0.42 10.1 5.2 1.1 8.7 0.1 2.8 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type DUF2183 PF09949.4 CDO75224.1 - 3.3e-18 65.4 0.0 6e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) PLRV_ORF5 PF01690.12 CDO75224.1 - 0.1 11.7 7.0 0.16 11.0 4.8 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DEC-1_N PF04625.8 CDO75224.1 - 1.8 7.1 10.8 2.9 6.4 7.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pkinase PF00069.20 CDO75226.1 - 1.5e-06 27.5 0.0 2.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PHP_C PF13263.1 CDO75226.1 - 0.11 12.0 0.1 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 PHP-associated Pkinase PF00069.20 CDO75227.1 - 6.3e-08 32.0 0.0 3.2e-07 29.7 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75227.1 - 0.0034 16.4 0.0 0.021 13.9 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase DUF3608 PF12257.3 CDO75228.1 - 3.1e-61 206.7 0.0 4.4e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 CDO75228.1 - 1.2e-13 50.5 0.0 2.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SicP-binding PF09119.5 CDO75228.1 - 0.17 11.6 0.0 0.51 10.0 0.0 1.8 2 0 0 2 2 2 0 SicP binding DUF3506 PF12014.3 CDO75229.1 - 3.5e-10 39.8 0.0 2e-07 30.9 0.0 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 CDO75229.1 - 1e-08 34.7 0.5 2.5e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO75229.1 - 3.5e-05 23.3 0.2 7.2e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 F-box domain Clathrin PF00637.15 CDO75230.1 - 9.2e-20 70.7 0.1 2e-19 69.5 0.1 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 CDO75230.1 - 0.00023 20.9 1.1 0.00058 19.6 0.8 1.7 1 0 0 1 1 1 1 Ring finger domain WD40 PF00400.27 CDO75230.1 - 0.0012 18.5 0.3 0.041 13.7 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Vps39_1 PF10366.4 CDO75230.1 - 0.0014 18.6 0.8 0.0099 15.8 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CDO75230.1 - 0.0037 17.4 0.0 0.0076 16.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 CDO75230.1 - 0.058 13.1 0.3 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CDO75230.1 - 0.083 12.5 0.9 0.18 11.5 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDO75230.1 - 0.12 12.2 1.1 0.25 11.2 0.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger UPF0239 PF06783.6 CDO75230.1 - 0.17 11.8 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) CENP-B_dimeris PF09026.5 CDO75230.1 - 3 8.1 12.2 7.5 6.8 8.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C3HC4_3 PF13920.1 CDO75230.1 - 4.7 6.9 6.1 2.4 7.8 0.3 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DNA_processg_A PF02481.10 CDO75232.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A RPN7 PF10602.4 CDO75233.1 - 4.7e-56 188.9 0.6 6.3e-56 188.5 0.4 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CDO75233.1 - 8.1e-16 58.2 0.0 2.2e-15 56.8 0.0 1.8 1 1 0 1 1 1 1 PCI domain SAC3_GANP PF03399.11 CDO75233.1 - 0.00011 21.8 0.6 0.00018 21.1 0.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TPR_15 PF13429.1 CDO75233.1 - 0.0024 16.9 0.3 0.0046 16.0 0.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Imm5 PF14423.1 CDO75233.1 - 0.02 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein Imm5 TPR_2 PF07719.12 CDO75233.1 - 0.022 14.6 0.4 0.1 12.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CDO75233.1 - 0.048 14.3 0.2 5.1 8.0 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CDO75233.1 - 0.98 9.4 6.9 0.26 11.2 1.5 2.5 3 1 0 3 3 3 0 Tetratricopeptide repeat PCI PF01399.22 CDO75234.1 - 2.6e-19 69.4 0.4 8e-19 67.9 0.2 2.0 2 0 0 2 2 2 1 PCI domain TPR_8 PF13181.1 CDO75234.1 - 0.0051 16.5 6.3 3.3 7.6 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.4 CDO75234.1 - 0.024 14.0 0.1 0.024 14.0 0.1 1.8 2 0 0 2 2 2 0 DDRGK domain TPR_7 PF13176.1 CDO75234.1 - 0.032 14.0 8.4 0.079 12.7 0.0 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Phage_GPO PF05929.6 CDO75234.1 - 0.035 13.3 0.1 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TPR_2 PF07719.12 CDO75234.1 - 0.098 12.6 8.3 5.7 7.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 CDO75234.1 - 0.14 12.9 9.1 88 4.1 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 CDO75234.1 - 0.47 10.3 6.1 0.27 11.1 0.1 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CDO75234.1 - 4 8.2 17.4 25 5.6 0.5 5.3 5 2 1 6 6 6 0 Tetratricopeptide repeat Fib_alpha PF08702.5 CDO75238.1 - 0.071 13.2 0.4 0.1 12.7 0.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Med21 PF11221.3 CDO75238.1 - 0.12 12.2 2.6 0.27 11.1 1.8 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Med9 PF07544.8 CDO75238.1 - 0.19 11.4 1.7 0.97 9.2 0.5 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF605 PF04652.11 CDO75240.1 - 0.11 11.8 1.9 0.13 11.6 1.3 1.1 1 0 0 1 1 1 0 Vta1 like DUF543 PF04418.7 CDO75241.1 - 0.087 12.7 2.7 0.2 11.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) BTB PF00651.26 CDO75242.1 - 0.00014 21.8 0.0 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain PEMT PF04191.8 CDO75243.1 - 2.6e-31 107.8 2.6 3.7e-31 107.3 1.3 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase MFS_1 PF07690.11 CDO75244.1 - 2.3e-28 98.9 39.0 1.6e-26 92.8 27.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC1 PF03109.11 CDO75244.1 - 1.8e-16 60.1 0.0 3.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Sugar_tr PF00083.19 CDO75244.1 - 1.8e-09 36.7 16.1 1.8e-09 36.7 11.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CDO75244.1 - 7.9e-07 27.6 6.7 1.4e-06 26.8 4.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF605 PF04652.11 CDO75245.1 - 3.9 6.7 7.7 4.4 6.6 5.3 1.1 1 0 0 1 1 1 0 Vta1 like Phosphorylase PF00343.15 CDO75246.1 - 2.8e-293 974.2 0.0 4.2e-176 586.9 0.0 2.0 1 1 0 2 2 2 2 Carbohydrate phosphorylase ETC_C1_NDUFA5 PF04716.9 CDO75248.1 - 2.5e-16 58.9 0.2 3.9e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region LSM PF01423.17 CDO75249.1 - 7.5e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF276 PF03434.8 CDO75249.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 DUF276 PHD PF00628.24 CDO75250.1 - 2.4e-09 36.7 9.0 2.4e-09 36.7 6.2 2.2 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.3 CDO75250.1 - 0.0024 17.3 4.4 0.018 14.5 0.2 2.3 2 0 0 2 2 2 2 CpG binding protein zinc finger C terminal domain HABP4_PAI-RBP1 PF04774.10 CDO75251.1 - 0.00042 20.7 13.0 0.00042 20.7 9.0 3.6 3 1 0 3 3 3 1 Hyaluronan / mRNA binding family His_Phos_1 PF00300.17 CDO75252.1 - 2.3e-23 83.0 0.0 3e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Memo PF01875.12 CDO75253.1 - 1.2e-71 240.8 0.0 1.3e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Ribosomal_L32e PF01655.13 CDO75254.1 - 1.9e-48 163.0 2.1 2.2e-48 162.8 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Pkinase PF00069.20 CDO75255.1 - 1.3e-44 152.3 0.0 6.2e-43 146.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75255.1 - 9.8e-17 60.8 0.0 3.6e-15 55.7 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO75255.1 - 3.3e-07 29.5 0.0 6.5e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDO75255.1 - 0.00061 18.9 0.0 0.0009 18.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDO75255.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family GTP_EFTU PF00009.22 CDO75256.1 - 1.5e-49 168.0 0.0 2.5e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CDO75256.1 - 1.1e-36 125.0 0.1 3.9e-36 123.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CDO75256.1 - 6.8e-17 61.3 0.9 6.8e-17 61.3 0.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CDO75256.1 - 2e-05 24.1 0.4 6.1e-05 22.5 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CDO75256.1 - 0.0028 17.5 0.1 0.0099 15.8 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.13 CDO75256.1 - 0.1 12.4 0.2 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain DLH PF01738.13 CDO75257.1 - 5.4e-06 25.8 0.0 0.057 12.6 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Acetyltransf_CG PF14542.1 CDO75258.1 - 0.041 13.7 0.0 0.09 12.6 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Abhydrolase_6 PF12697.2 CDO75259.1 - 1.5e-18 67.5 2.7 2.7e-18 66.6 1.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO75259.1 - 3.8e-16 59.3 0.6 5.5e-08 32.6 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO75259.1 - 3.8e-13 49.4 0.1 4.7e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CDO75259.1 - 1.5e-06 28.0 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.11 CDO75259.1 - 6.4e-05 22.4 0.1 0.29 10.5 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 CDO75259.1 - 0.0027 17.1 0.0 0.0054 16.1 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 CDO75259.1 - 0.003 16.8 0.1 0.61 9.3 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family DUF2048 PF09752.4 CDO75259.1 - 0.0045 15.9 0.8 1.1 8.0 0.2 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2048) Peptidase_S9 PF00326.16 CDO75259.1 - 0.0075 15.5 0.1 0.022 13.9 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family UPF0227 PF05728.7 CDO75259.1 - 0.017 14.8 0.1 0.82 9.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) LIP PF03583.9 CDO75259.1 - 0.14 11.3 0.5 0.93 8.6 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase Elong_Iki1 PF10483.4 CDO75260.1 - 1.4e-06 27.9 2.1 0.0014 18.1 0.0 2.6 2 1 0 2 2 2 2 Elongator subunit Iki1 AAA_25 PF13481.1 CDO75260.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 CDO75262.1 - 2.5e-88 296.4 0.0 2.9e-88 296.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2 PF00152.15 CDO75263.1 - 2e-80 270.0 0.1 3.2e-80 269.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CDO75263.1 - 1.1e-08 34.8 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CDO75263.1 - 0.0094 15.1 0.4 0.83 8.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_S49_N PF08496.5 CDO75263.1 - 0.067 12.9 2.3 0.15 11.8 1.6 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SPRY PF00622.23 CDO75265.1 - 9.8e-17 61.2 0.0 1.4e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 SPRY domain CBS PF00571.23 CDO75266.1 - 1.2e-30 104.9 0.9 3e-12 46.1 0.0 4.4 4 0 0 4 4 4 4 CBS domain Mito_carr PF00153.22 CDO75267.1 - 1.3e-59 197.9 0.0 1e-18 66.8 0.2 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein RhoGEF PF00621.15 CDO75268.1 - 2e-43 148.3 0.0 3.1e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 CDO75268.1 - 6.2e-16 57.6 18.4 1.2e-06 27.9 0.7 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO75268.1 - 9.7e-12 44.4 6.0 4.7e-07 29.4 1.1 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CDO75268.1 - 0.00063 19.4 10.5 7.2 7.0 0.1 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 CDO75268.1 - 0.0062 16.5 4.3 15 6.3 0.0 4.9 5 0 0 5 5 5 1 Leucine rich repeat Ribosomal_S15 PF00312.17 CDO75268.1 - 0.094 12.4 0.1 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S15 MSP1_C PF07462.6 CDO75269.1 - 1.2 7.4 2.4 2.4 6.4 1.6 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus G-alpha PF00503.15 CDO75270.1 - 4.4e-75 252.7 0.0 4.3e-74 249.5 0.0 1.9 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CDO75270.1 - 1.8e-06 27.2 0.0 3.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family UDPGT PF00201.13 CDO75271.1 - 5.2e-20 71.4 0.1 8.2e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CDO75271.1 - 0.00017 21.3 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain IBR PF01485.16 CDO75272.1 - 1.1e-13 50.7 25.5 5.5e-10 38.9 10.6 4.0 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 CDO75272.1 - 1.1e-05 25.3 7.5 1.1e-05 25.3 5.2 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO75272.1 - 0.00011 21.7 7.8 0.00011 21.7 5.4 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO75272.1 - 0.00028 20.6 7.2 0.00028 20.6 5.0 3.6 3 1 0 3 3 3 2 Ring finger domain DUF1488 PF07369.6 CDO75272.1 - 0.046 13.5 0.3 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) HSP70 PF00012.15 CDO75273.1 - 3.1e-162 540.6 0.8 3.1e-162 540.6 0.5 1.7 1 1 1 2 2 2 1 Hsp70 protein tRNA-synt_2 PF00152.15 CDO75273.1 - 5.1e-83 278.6 0.0 1.1e-82 277.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) MreB_Mbl PF06723.8 CDO75273.1 - 6.2e-11 41.4 0.2 3.9e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein tRNA_anti-codon PF01336.20 CDO75273.1 - 1e-09 38.0 0.0 5.8e-09 35.6 0.0 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CDO75273.1 - 2.8e-09 36.5 0.4 0.00083 18.6 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class II core domain (F) DUF445 PF04286.7 CDO75273.1 - 0.18 11.3 7.9 6.5 6.1 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) WD40 PF00400.27 CDO75275.1 - 3.8e-12 45.5 9.9 3.1e-05 23.6 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat IKI3 PF04762.7 CDO75275.1 - 0.0074 14.1 0.1 0.012 13.4 0.1 1.3 1 0 0 1 1 1 1 IKI3 family Gmad1 PF10647.4 CDO75275.1 - 0.14 11.5 3.0 3.6 6.9 0.4 3.4 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain WD40 PF00400.27 CDO75276.1 - 5.7e-15 54.5 17.2 2e-05 24.2 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat NACHT PF05729.7 CDO75276.1 - 1.7e-06 27.7 0.1 6.4e-06 25.9 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 CDO75276.1 - 8.7e-05 22.6 0.0 0.00028 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CDO75276.1 - 0.033 13.0 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 CDO75276.1 - 0.072 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain PX PF00787.19 CDO75277.1 - 8e-26 90.0 0.0 1e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.22 CDO75278.1 - 8.9e-27 92.6 2.5 1.9e-14 53.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 CDO75279.1 - 3.8e-38 128.0 32.4 5.7e-08 32.3 0.1 10.6 11 0 0 11 11 11 7 WD domain, G-beta repeat NACHT PF05729.7 CDO75279.1 - 4.6e-06 26.3 0.1 1.7e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 NACHT domain PD40 PF07676.7 CDO75279.1 - 0.00063 19.3 0.5 21 4.8 0.0 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 CDO75279.1 - 0.0011 19.0 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cytochrom_D1 PF02239.11 CDO75279.1 - 0.0014 17.0 0.1 0.41 8.8 0.0 3.3 2 1 1 3 3 3 2 Cytochrome D1 heme domain KAP_NTPase PF07693.9 CDO75279.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.1 CDO75279.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CDO75279.1 - 0.062 13.0 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 CDO75279.1 - 0.072 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Proteasome_A_N PF10584.4 CDO75279.1 - 2.3 7.6 12.2 20 4.5 0.0 5.6 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Sugar_tr PF00083.19 CDO75280.1 - 1.4e-74 251.3 18.6 1.7e-74 251.0 12.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO75280.1 - 8.8e-28 97.0 43.3 4.4e-24 84.8 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDO75280.1 - 3e-05 22.6 25.5 4.1e-05 22.1 0.5 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein Peptidase_M24 PF00557.19 CDO75281.1 - 4.6e-43 147.2 0.0 7.9e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CDO75281.1 - 4.3e-16 59.6 0.0 1.1e-15 58.3 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain NOGCT PF08155.6 CDO75282.1 - 1.4e-29 101.5 1.1 1.4e-29 101.5 0.8 2.1 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.9 CDO75282.1 - 3.6e-29 100.4 0.1 6.8e-29 99.5 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 CDO75282.1 - 3e-17 62.6 0.0 7e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Cauli_VI PF01693.11 CDO75282.1 - 3.6e-13 49.2 0.0 1.1e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 Caulimovirus viroplasmin FeoB_N PF02421.13 CDO75282.1 - 8.3e-10 38.1 0.0 1.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RNase_H PF00075.19 CDO75282.1 - 1.6e-08 34.9 1.2 7.8e-05 23.0 0.0 2.7 1 1 1 2 2 2 2 RNase H Miro PF08477.8 CDO75282.1 - 0.00039 20.8 0.0 0.00096 19.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 CDO75282.1 - 0.0085 15.2 0.0 0.049 12.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CDO75282.1 - 0.022 14.5 0.4 3.7 7.3 0.0 2.9 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.11 CDO75282.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 AIG1 family MobB PF03205.9 CDO75282.1 - 0.088 12.5 0.1 0.81 9.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PSD4 PF07631.6 CDO75283.1 - 0.012 15.9 0.1 0.035 14.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) RRM_1 PF00076.17 CDO75284.1 - 7e-58 192.1 0.0 3.7e-18 64.9 0.0 6.2 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO75284.1 - 2.1e-43 146.1 0.0 2e-11 43.7 0.0 5.1 4 1 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO75284.1 - 1.3e-14 53.8 0.0 0.028 14.2 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO75284.1 - 0.017 14.8 0.0 23 4.8 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif TFIIA PF03153.8 CDO75284.1 - 0.082 12.7 20.6 0.01 15.7 10.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1180 PF06679.7 CDO75284.1 - 0.16 11.8 2.3 0.34 10.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SAPS PF04499.10 CDO75284.1 - 3 6.3 7.2 7.7 5.0 5.0 1.7 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NTP_transf_2 PF01909.18 CDO75285.1 - 0.023 14.9 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Paf67 PF10255.4 CDO75286.1 - 1.6e-147 491.6 0.0 2e-147 491.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 CDO75286.1 - 0.074 13.0 0.0 0.56 10.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat OTOS PF15182.1 CDO75286.1 - 0.18 11.5 0.8 8.7 6.0 0.1 2.6 2 0 0 2 2 2 0 Otospiralin SSF PF00474.12 CDO75287.1 - 3.1e-14 52.4 40.9 3.9e-14 52.1 24.9 2.6 2 1 0 2 2 2 1 Sodium:solute symporter family Glyco_hydr_30_2 PF14587.1 CDO75288.1 - 4.7e-26 91.6 0.0 5.7e-23 81.4 0.0 2.2 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_cc PF11790.3 CDO75288.1 - 0.00053 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_30 PF02055.11 CDO75288.1 - 0.0086 14.3 0.0 0.021 13.0 0.0 1.5 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Curlin_rpt PF07012.7 CDO75288.1 - 0.011 15.4 0.1 0.043 13.5 0.1 2.1 1 0 0 1 1 1 0 Curlin associated repeat DUF1824 PF08854.5 CDO75288.1 - 0.049 13.2 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) DEAD PF00270.24 CDO75294.1 - 4.5e-16 58.7 0.0 1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO75294.1 - 1.3e-11 44.1 0.0 6.4e-11 41.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO75294.1 - 0.0013 18.6 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC_6 PF15288.1 CDO75294.1 - 0.0057 16.2 1.6 0.015 14.9 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle AhpC-TSA_2 PF13911.1 CDO75294.1 - 0.017 15.0 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Peptidase_M2 PF01401.13 CDO75294.1 - 0.11 10.7 0.0 0.16 10.1 0.0 1.2 1 0 0 1 1 1 0 Angiotensin-converting enzyme APH PF01636.18 CDO75295.1 - 0.0016 18.2 0.4 0.0039 16.9 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family ETC_C1_NDUFA4 PF04800.7 CDO75296.1 - 9.4e-35 118.5 0.1 1.5e-34 117.9 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF221 PF02714.10 CDO75297.1 - 1e-46 159.3 16.7 2.2e-46 158.2 11.6 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CDO75297.1 - 6.1e-20 71.3 0.3 2.3e-19 69.5 0.2 2.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CDO75297.1 - 1.3e-06 28.8 0.1 0.018 15.5 0.1 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) DUF3779 PF12621.3 CDO75297.1 - 0.0069 16.2 0.3 0.016 15.0 0.2 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein RRM_6 PF14259.1 CDO75297.1 - 0.063 13.2 0.0 0.81 9.7 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDO75297.1 - 0.17 11.5 0.1 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4051 PF13260.1 CDO75297.1 - 1.2 8.5 5.7 0.18 11.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) CBM_1 PF00734.13 CDO75298.1 - 6.7e-12 44.8 8.6 6.7e-12 44.8 6.0 1.8 1 1 0 1 1 1 1 Fungal cellulose binding domain DUF663 PF04950.7 CDO75299.1 - 5.5e-90 301.3 1.4 1e-89 300.4 0.0 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CDO75299.1 - 3e-28 97.1 0.0 8e-28 95.8 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CDO75299.1 - 5.3e-07 29.2 0.0 0.00015 21.3 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CDO75299.1 - 2.8e-05 24.2 0.0 7.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDO75299.1 - 4.9e-05 24.1 2.6 0.00011 23.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CDO75299.1 - 9.7e-05 22.4 0.0 0.00037 20.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 CDO75299.1 - 0.00014 21.5 0.1 0.00043 19.9 0.1 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 CDO75299.1 - 0.00049 20.2 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CDO75299.1 - 0.00069 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 CDO75299.1 - 0.00075 19.4 0.1 0.0029 17.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 CDO75299.1 - 0.00087 19.6 2.1 0.00098 19.4 0.0 2.2 2 0 0 2 2 1 1 ABC transporter RNA_helicase PF00910.17 CDO75299.1 - 0.001 19.2 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.18 CDO75299.1 - 0.0011 18.9 0.2 0.0048 16.8 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CDO75299.1 - 0.0011 18.4 0.2 0.0035 16.8 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 CDO75299.1 - 0.0011 18.3 0.0 0.0053 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CDO75299.1 - 0.0017 18.2 0.0 0.016 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CDO75299.1 - 0.0034 17.1 0.3 0.0075 15.9 0.2 1.5 1 0 0 1 1 1 1 NTPase AAA_24 PF13479.1 CDO75299.1 - 0.0035 16.9 0.1 0.01 15.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CDO75299.1 - 0.0049 16.3 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain NB-ARC PF00931.17 CDO75299.1 - 0.0071 15.2 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Miro PF08477.8 CDO75299.1 - 0.0086 16.5 0.0 0.03 14.8 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_5 PF07728.9 CDO75299.1 - 0.015 15.0 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CDO75299.1 - 0.015 15.0 0.1 0.038 13.7 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 CDO75299.1 - 0.015 15.5 0.1 0.015 15.5 0.0 3.4 5 0 0 5 5 1 0 AAA domain cobW PF02492.14 CDO75299.1 - 0.021 14.2 0.1 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CDO75299.1 - 0.029 13.5 0.0 0.074 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 CDO75299.1 - 0.03 14.2 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.12 CDO75299.1 - 0.17 11.3 0.0 0.4 10.1 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.1 CDO75299.1 - 0.58 9.6 5.9 1.8 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CDO75299.1 - 2 8.7 0.0 2 8.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 CDO75299.1 - 5.4 6.7 7.9 1.5 8.6 0.0 3.5 4 0 0 4 4 3 0 Domain of unknown function DUF87 Cep57_MT_bd PF06657.8 CDO75300.1 - 2.3e-24 85.1 0.1 2.3e-24 85.1 0.0 4.0 4 1 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 CDO75300.1 - 1.1e-08 34.9 12.4 1.1e-08 34.9 8.6 4.0 3 2 1 4 4 4 1 Centrosome localisation domain of PPC89 IFT57 PF10498.4 CDO75300.1 - 0.24 10.1 14.6 3.6 6.2 10.1 2.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 HALZ PF02183.13 CDO75300.1 - 0.38 10.4 7.5 0.43 10.3 0.0 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4279 PF14106.1 CDO75300.1 - 1 9.2 4.6 11 5.9 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4279) ABC_membrane PF00664.18 CDO75301.1 - 5.3e-87 291.7 24.0 3.1e-45 154.7 3.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CDO75301.1 - 3.3e-63 212.0 0.0 1.6e-32 112.7 0.0 3.8 3 0 0 3 3 3 3 ABC transporter SMC_N PF02463.14 CDO75301.1 - 7.8e-14 51.4 0.0 0.00022 20.5 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDO75301.1 - 1.5e-09 38.2 0.1 0.028 14.3 0.0 4.3 2 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CDO75301.1 - 4.1e-08 32.6 1.3 0.00038 19.9 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 CDO75301.1 - 9.6e-07 28.6 0.3 0.0073 16.1 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 CDO75301.1 - 1.1e-06 29.4 0.1 0.12 13.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 CDO75301.1 - 1.6e-06 28.2 1.5 0.014 15.4 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 CDO75301.1 - 9.2e-06 24.9 0.0 0.044 12.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CDO75301.1 - 3.6e-05 23.8 1.8 0.94 9.6 0.0 4.4 4 1 0 4 4 3 1 AAA domain AAA_25 PF13481.1 CDO75301.1 - 0.00019 20.8 0.0 0.15 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CDO75301.1 - 0.00049 20.4 4.1 0.17 12.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.4 CDO75301.1 - 0.00083 18.0 1.0 0.037 12.6 0.0 3.4 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA PF00004.24 CDO75301.1 - 0.00095 19.3 0.8 16 5.7 0.1 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CDO75301.1 - 0.0011 18.8 0.0 1.8 8.4 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 CDO75301.1 - 0.0013 18.9 0.0 2.7 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CDO75301.1 - 0.0021 17.9 0.0 3.6 7.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CDO75301.1 - 0.0022 17.0 0.0 2.5 7.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.9 CDO75301.1 - 0.0052 16.5 0.2 3.1 7.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CDO75301.1 - 0.017 14.5 1.0 10 5.4 0.0 3.5 4 0 0 4 4 3 0 AAA-like domain MobB PF03205.9 CDO75301.1 - 0.021 14.5 0.3 9.1 5.9 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 CDO75301.1 - 0.022 15.2 0.1 16 6.0 0.0 3.2 3 0 0 3 3 2 0 Miro-like protein MMR_HSR1 PF01926.18 CDO75301.1 - 0.028 14.3 0.0 14 5.6 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 CDO75301.1 - 0.029 14.3 4.1 0.85 9.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.15 CDO75301.1 - 0.033 12.8 0.0 0.033 12.8 0.0 3.3 3 1 1 4 4 3 0 G-protein alpha subunit ATP-synt_ab PF00006.20 CDO75301.1 - 0.041 13.3 1.1 14 5.0 0.0 3.5 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 CDO75301.1 - 0.049 13.1 0.1 4.3 6.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 CDO75301.1 - 0.051 13.7 0.1 6 7.0 0.0 3.1 3 0 0 3 3 2 0 RNA helicase PRK PF00485.13 CDO75301.1 - 0.055 13.0 0.0 4.5 6.7 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 CDO75301.1 - 0.074 11.9 0.0 4.2 6.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.12 CDO75301.1 - 0.093 12.5 6.4 11 5.8 0.0 4.1 5 0 0 5 5 4 0 Domain of unknown function DUF87 AAA_15 PF13175.1 CDO75301.1 - 0.095 11.7 0.0 2.4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF912 PF06024.7 CDO75301.1 - 0.96 9.5 2.4 7.2 6.7 0.9 3.1 4 0 0 4 4 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CDC45 PF02724.9 CDO75301.1 - 3.8 5.4 7.9 1.4 6.8 3.0 2.0 3 0 0 3 3 3 0 CDC45-like protein HA2 PF04408.18 CDO75302.1 - 2e-25 88.7 0.3 2.2e-24 85.4 0.1 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CDO75302.1 - 2e-15 56.6 0.0 5.1e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CDO75302.1 - 1.2e-10 41.0 0.0 3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO75302.1 - 1.6e-07 30.9 0.2 2.9e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CDO75302.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CDO75302.1 - 0.0089 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 CDO75302.1 - 0.017 14.2 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 CDO75302.1 - 0.022 13.9 0.0 0.071 12.3 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.1 CDO75302.1 - 0.027 14.0 0.2 0.059 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CDO75302.1 - 0.052 13.2 0.9 0.14 11.8 0.6 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 CDO75302.1 - 0.059 13.6 0.1 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CDO75302.1 - 0.13 12.0 0.0 5.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Nipped-B_C PF12830.2 CDO75304.1 - 7.4e-48 162.6 0.2 2.7e-47 160.8 0.1 2.1 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 CDO75304.1 - 2.8e-14 52.6 0.5 1e-13 50.9 0.1 2.2 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 CDO75304.1 - 0.0014 18.4 0.5 0.66 10.2 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat UDPGT PF00201.13 CDO75308.1 - 5.7e-20 71.3 0.1 9.3e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CDO75308.1 - 0.00039 20.1 0.1 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CDO75308.1 - 0.035 13.3 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 APG5 PF04106.7 CDO75309.1 - 1.2e-05 24.8 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF1669 PF07894.7 CDO75309.1 - 0.037 13.2 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) RVT_1 PF00078.22 CDO75310.1 - 1.8e-22 79.7 0.0 3.6e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sugar_tr PF00083.19 CDO75311.1 - 5.3e-109 364.7 16.7 6.1e-109 364.5 11.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO75311.1 - 1.8e-23 82.8 27.4 1.8e-23 82.8 19.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily rve PF00665.21 CDO75313.1 - 3.6e-16 59.3 0.1 3.5e-14 52.9 0.1 2.6 1 1 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 CDO75313.1 - 6.3e-16 58.0 0.0 1.3e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO75313.1 - 2.1e-11 43.6 0.0 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO75313.1 - 4.5e-09 35.8 0.1 1.2e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CDO75313.1 - 5.2e-05 22.6 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Myb_DNA-bind_3 PF12776.2 CDO75315.1 - 3.4e-08 34.0 0.0 1e-07 32.4 0.0 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain UBN2_2 PF14227.1 CDO75317.1 - 1.6e-09 37.3 0.1 3.2e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO75317.1 - 0.00011 21.9 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO75317.1 - 0.033 13.7 0.0 0.084 12.4 0.0 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO75317.1 - 0.079 12.4 1.1 0.22 10.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) zf-CCHC_4 PF14392.1 CDO75317.1 - 0.34 10.6 2.5 0.67 9.6 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Uds1 PF15456.1 CDO75317.1 - 5.7 6.9 11.2 0.71 9.8 0.1 2.9 3 0 0 3 3 3 0 Up-regulated During Septation Sad1_UNC PF07738.8 CDO75318.1 - 1.1e-17 64.0 0.0 1.2e-14 54.2 0.0 2.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal WD40 PF00400.27 CDO75320.1 - 9.7e-15 53.8 1.5 1.2e-07 31.3 0.0 4.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Transposase_21 PF02992.9 CDO75322.1 - 8.5e-20 70.8 0.0 1.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO75322.1 - 0.00028 20.3 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) rve PF00665.21 CDO75323.1 - 2.5e-22 79.2 0.0 4e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CDO75323.1 - 0.00026 20.3 0.0 0.00067 19.0 0.0 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Imm47 PF15586.1 CDO75323.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 47 DNA_pol_E_B PF04042.11 CDO75324.1 - 6.2e-29 100.7 0.2 9.1e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 CDO75324.1 - 5.3e-25 88.4 0.0 9.3e-13 48.2 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal Metallophos_3 PF14582.1 CDO75324.1 - 0.0031 16.7 0.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily Pkinase PF00069.20 CDO75325.1 - 0.027 13.6 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Macro_2 PF14519.1 CDO75326.1 - 0.00022 20.4 0.1 0.00074 18.7 0.0 1.7 1 1 0 1 1 1 1 Macro-like domain MerE PF05052.7 CDO75327.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.3 2 1 1 3 3 3 0 MerE protein Glyco_hydro_88 PF07470.8 CDO75328.1 - 1.3e-17 63.9 1.4 1.7e-17 63.4 1.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DASH_Dad1 PF08649.5 CDO75329.1 - 3.7e-16 58.5 0.3 4.4e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.5 CDO75329.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 Pkinase PF00069.20 CDO75330.1 - 3.1e-59 200.2 0.2 2.2e-51 174.5 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75330.1 - 5.2e-31 107.6 0.0 3.1e-27 95.2 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase HR1 PF02185.11 CDO75330.1 - 2.5e-24 84.8 18.3 5e-16 58.1 4.3 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 CDO75330.1 - 1.8e-20 72.4 27.2 3.6e-11 42.6 7.0 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CDO75330.1 - 9.7e-10 38.8 0.3 6.2e-09 36.2 0.1 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.25 CDO75330.1 - 0.066 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 C2 domain Uds1 PF15456.1 CDO75330.1 - 1.5 8.7 19.8 0.11 12.5 2.5 2.8 3 0 0 3 3 3 0 Up-regulated During Septation Endosulfine PF04667.12 CDO75332.1 - 2e-19 69.3 1.2 3e-19 68.7 0.4 1.5 1 1 1 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF2454 PF10521.4 CDO75333.1 - 0.073 12.0 0.2 0.23 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) Transposase_21 PF02992.9 CDO75335.1 - 3.1e-14 52.6 0.0 5.2e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF433 PF04255.9 CDO75336.1 - 0.092 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) EXS PF03124.9 CDO75340.1 - 1.4e-52 178.8 1.6 5.8e-22 78.1 0.0 3.0 2 1 1 3 3 3 3 EXS family 2-Hacid_dh_C PF02826.14 CDO75341.1 - 1.5e-47 161.0 0.0 2.2e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CDO75341.1 - 2.2e-18 65.9 0.0 3.2e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CDO75341.1 - 1.3e-06 28.3 0.0 6.1e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 CDO75341.1 - 0.071 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DPBB_1 PF03330.13 CDO75342.1 - 8.5e-05 22.4 0.2 0.00031 20.6 0.0 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pro-kuma_activ PF09286.6 CDO75343.1 - 3.7e-27 95.1 0.0 4.4e-27 94.8 0.0 1.0 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Bromodomain PF00439.20 CDO75344.1 - 8.5e-28 96.1 0.2 1.8e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CDO75344.1 - 4.6e-07 29.9 0.7 8.7e-07 29.0 0.5 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO75344.1 - 1.3e-05 25.1 0.2 3.9e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4259 PF14078.1 CDO75344.1 - 0.022 15.2 0.5 0.046 14.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Pro_isomerase PF00160.16 CDO75345.1 - 7.4e-47 159.4 0.2 1e-46 158.9 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 CDO75345.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain DEAD PF00270.24 CDO75346.1 - 3.9e-36 124.0 0.0 6.7e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CDO75346.1 - 1.7e-18 65.9 0.2 3.2e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CDO75346.1 - 1.4e-16 60.1 0.0 2.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO75346.1 - 0.0089 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Nop14 PF04147.7 CDO75346.1 - 0.66 7.8 34.9 0.0039 15.2 16.9 2.1 2 0 0 2 2 2 0 Nop14-like family MOZ_SAS PF01853.13 CDO75347.1 - 1.2e-84 282.2 0.5 1.8e-84 281.6 0.4 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CDO75347.1 - 1.7e-18 66.0 0.0 4.1e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_11 PF08279.7 CDO75347.1 - 0.0077 15.8 0.1 0.02 14.5 0.1 1.7 1 0 0 1 1 1 1 HTH domain HTH_Mga PF08280.6 CDO75347.1 - 0.013 15.2 0.4 0.03 14.0 0.3 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Acetyltransf_1 PF00583.19 CDO75347.1 - 0.036 14.0 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family HTH_IclR PF09339.5 CDO75347.1 - 0.15 11.7 0.1 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain Gemini_AL2 PF01440.11 CDO75347.1 - 0.26 11.3 1.7 0.75 9.8 1.2 1.7 1 0 0 1 1 1 0 Geminivirus AL2 protein LAG1-DNAbind PF09271.6 CDO75348.1 - 5.9e-34 117.5 0.0 1e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 CDO75348.1 - 1.3e-12 47.7 0.0 4.3e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain CAGE1 PF15066.1 CDO75350.1 - 0.00084 17.9 1.6 0.0012 17.3 1.1 1.2 1 0 0 1 1 1 1 Cancer-associated gene protein 1 family DUF4200 PF13863.1 CDO75350.1 - 0.027 14.3 4.2 0.047 13.6 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Pkinase PF00069.20 CDO75351.1 - 1.7e-54 184.7 0.0 3.6e-54 183.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75351.1 - 1.7e-21 76.5 0.0 2.7e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO75351.1 - 5.7e-05 22.9 1.0 0.00029 20.6 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CDO75351.1 - 0.002 17.4 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Put_Phosphatase PF06888.7 CDO75352.1 - 4.3e-45 153.7 0.1 5.6e-31 107.5 0.0 2.0 1 1 1 2 2 2 2 Putative Phosphatase p450 PF00067.17 CDO75353.1 - 2.6e-65 220.7 0.6 8.3e-44 149.8 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 MinE PF03776.9 CDO75353.1 - 0.11 12.0 0.2 0.87 9.1 0.1 2.3 1 1 1 2 2 2 0 Septum formation topological specificity factor MinE BSD PF03909.12 CDO75354.1 - 4e-22 77.7 0.1 4.7e-14 51.8 0.0 2.5 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 CDO75354.1 - 6.8e-08 32.0 0.0 1.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Semialdhyde_dh PF01118.19 CDO75354.1 - 0.021 15.1 0.1 0.61 10.3 0.0 3.2 3 1 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain GvpG PF05120.7 CDO75354.1 - 0.068 12.9 0.1 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 Gas vesicle protein G CASP_C PF08172.7 CDO75355.1 - 4.3e-71 238.8 2.0 4.3e-71 238.8 1.4 4.4 3 2 1 4 4 4 1 CASP C terminal CtIP_N PF10482.4 CDO75355.1 - 0.0018 18.0 0.7 0.0018 18.0 0.5 5.8 4 2 1 5 5 5 1 Tumour-suppressor protein CtIP N-terminal domain APG6 PF04111.7 CDO75355.1 - 0.82 8.6 63.3 0.075 12.0 16.1 4.2 3 1 1 4 4 4 0 Autophagy protein Apg6 DUF1664 PF07889.7 CDO75355.1 - 1.6 8.5 32.9 1.9 8.2 3.4 5.0 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) GnsAB PF08178.6 CDO75355.1 - 6.4 6.5 13.4 3.2 7.4 1.1 4.1 3 0 0 3 3 3 0 GnsA/GnsB family MscS_porin PF12795.2 CDO75355.1 - 9.3 5.4 67.5 0.052 12.8 8.4 4.7 4 2 0 4 4 4 0 Mechanosensitive ion channel porin domain IncA PF04156.9 CDO75355.1 - 9.7 5.7 76.1 0.79 9.2 1.4 6.0 3 1 1 4 4 4 0 IncA protein Ribosomal_S9 PF00380.14 CDO75356.1 - 1.7e-33 115.4 0.0 5.6e-31 107.3 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein S9/S16 BRE1 PF08647.6 CDO75357.1 - 6.2e-15 54.9 8.4 6.2e-15 54.9 5.8 7.1 7 2 0 7 7 7 2 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 CDO75357.1 - 0.0004 19.6 24.6 0.099 11.8 0.1 5.4 3 2 2 6 6 6 5 Reovirus sigma C capsid protein DivIVA PF05103.8 CDO75357.1 - 0.0086 16.1 2.7 0.0086 16.1 1.9 7.8 3 1 6 9 9 9 1 DivIVA protein DASH_Duo1 PF08651.5 CDO75358.1 - 1.6e-14 53.1 1.1 3.1e-14 52.2 0.7 1.5 1 0 0 1 1 1 1 DASH complex subunit Duo1 MAP7 PF05672.6 CDO75358.1 - 2.2 7.6 41.3 0.11 11.8 21.2 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family GAGA_bind PF06217.7 CDO75358.1 - 4.3 7.2 11.0 6.1 6.7 7.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CDO75358.1 - 4.5 7.0 13.2 1.9 8.3 0.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2367 PF10164.4 CDO75359.1 - 1.8e-05 24.5 1.7 3.1e-05 23.7 1.2 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Methyltransf_31 PF13847.1 CDO75360.1 - 1.2e-14 54.1 0.2 2.1e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CDO75360.1 - 8e-12 44.8 0.0 1.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CDO75360.1 - 1.1e-11 45.2 0.1 3.4e-11 43.7 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO75360.1 - 3.6e-11 43.3 0.0 7.6e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO75360.1 - 1.4e-09 37.9 0.0 5.3e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 CDO75360.1 - 2e-08 33.6 0.0 2.7e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.9 CDO75360.1 - 7.3e-08 31.9 0.1 1.3e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CDO75360.1 - 1e-07 31.8 0.0 2.3e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO75360.1 - 1.5e-07 31.7 0.0 3.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CDO75360.1 - 1.9e-07 30.0 0.0 2.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 CDO75360.1 - 2.9e-07 30.7 0.0 5.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CDO75360.1 - 8.5e-07 28.3 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 CDO75360.1 - 0.00014 21.5 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 CDO75360.1 - 0.00019 20.6 0.1 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 CDO75360.1 - 0.00026 21.0 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.9 CDO75360.1 - 0.00036 19.7 1.0 0.0015 17.7 0.7 1.9 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 CDO75360.1 - 0.0013 18.1 0.1 0.0021 17.5 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 CDO75360.1 - 0.0022 17.5 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 CDO75360.1 - 0.0027 17.3 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CDO75360.1 - 0.0042 17.9 0.0 0.013 16.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CDO75360.1 - 0.023 13.7 0.1 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 CDO75360.1 - 0.024 13.6 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.10 CDO75360.1 - 0.047 13.0 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DOT1 PF08123.8 CDO75360.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 F-box-like PF12937.2 CDO75361.1 - 4.3e-05 23.1 0.1 0.00014 21.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO75361.1 - 0.024 14.2 0.0 0.093 12.4 0.0 2.0 2 0 0 2 2 2 0 F-box domain Tyrosinase PF00264.15 CDO75362.1 - 4.1e-15 56.5 0.5 4.5e-15 56.4 0.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF600 PF04634.7 CDO75363.1 - 0.33 10.9 0.0 0.65 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF600 TATR PF03430.8 CDO75363.1 - 0.64 8.6 4.1 1.3 7.5 2.8 1.4 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DDE_Tnp_4 PF13359.1 CDO75364.1 - 1e-22 80.3 0.0 1.3e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CDO75364.1 - 0.0035 16.7 0.1 0.0059 16.0 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO75364.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.16 CDO75364.1 - 0.024 14.1 0.2 0.089 12.3 0.1 1.8 1 1 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 CDO75365.1 - 2.1e-05 25.0 0.3 4.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CDO75365.1 - 0.00023 21.2 0.4 0.00062 19.8 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pap_E4 PF02711.9 CDO75365.1 - 2.4 9.0 5.4 4.4 8.2 0.8 2.7 2 1 0 2 2 2 0 E4 protein Adap_comp_sub PF00928.16 CDO75366.1 - 1.8e-67 227.2 0.1 8.7e-67 224.9 0.1 1.9 1 1 0 1 1 1 1 Adaptor complexes medium subunit family HAT PF02184.11 CDO75366.1 - 1.5e-22 78.9 56.8 7.3e-08 32.0 1.8 13.0 14 0 0 14 14 13 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 CDO75366.1 - 1.9e-22 77.6 24.5 0.004 17.6 0.1 11.6 7 3 6 13 13 12 5 Tetratricopeptide repeat TPR_2 PF07719.12 CDO75366.1 - 1.2e-13 49.8 1.4 0.081 12.8 0.0 8.0 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO75366.1 - 2.2e-13 50.2 1.7 0.21 11.9 0.0 7.2 8 1 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 CDO75366.1 - 1.8e-11 44.3 22.9 4.9e-05 23.8 0.1 7.7 7 1 0 8 8 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 CDO75366.1 - 2.5e-09 36.6 3.7 0.009 15.6 0.0 6.2 5 2 2 7 7 7 3 TPR repeat TPR_12 PF13424.1 CDO75366.1 - 1e-07 31.7 4.8 0.41 10.6 0.0 6.4 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDO75366.1 - 5.7e-07 29.2 0.0 0.11 12.7 0.0 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CDO75366.1 - 3.6e-05 22.9 20.5 0.027 13.5 0.2 5.9 3 3 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CDO75366.1 - 4.1e-05 23.0 14.4 0.86 9.5 0.0 8.0 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO75366.1 - 6e-05 22.5 0.6 5.1 7.1 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDO75366.1 - 6.1e-05 23.2 5.9 19 6.0 0.0 7.1 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CDO75366.1 - 0.00028 20.3 0.0 4.4 7.0 0.0 5.3 7 0 0 7 7 7 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 CDO75366.1 - 0.033 13.9 20.7 0.029 14.1 0.7 5.8 4 2 1 5 5 5 0 U3 small nucleolar RNA-associated protein 6 SH3_5 PF08460.5 CDO75366.1 - 0.049 13.5 0.3 0.98 9.3 0.1 2.8 2 0 0 2 2 2 0 Bacterial SH3 domain UQ_con PF00179.21 CDO75367.1 - 2.5e-44 150.1 0.0 4.6e-40 136.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDO75367.1 - 2.1e-07 30.7 0.1 1.3e-06 28.2 0.0 1.9 1 1 1 2 2 2 1 Prokaryotic E2 family B CTP_transf_1 PF01148.15 CDO75368.1 - 9e-11 41.9 3.7 2.3e-07 30.7 0.1 2.9 1 1 1 2 2 2 2 Cytidylyltransferase family Fer2 PF00111.22 CDO75369.1 - 4.8e-11 42.2 0.1 6.6e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Phage_T7_Capsid PF05396.6 CDO75370.1 - 0.041 14.0 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Phage T7 capsid assembly protein Pkinase PF00069.20 CDO75371.1 - 3.9e-05 22.9 0.0 6.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 CDO75371.1 - 0.0003 20.1 0.0 0.00057 19.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CDO75371.1 - 0.00033 20.4 1.3 0.02 14.6 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 CDO75371.1 - 0.0082 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 CDO75371.1 - 0.02 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 CDO75371.1 - 0.11 11.5 0.0 0.36 9.8 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.15 CDO75371.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase BRCT PF00533.21 CDO75372.1 - 7.5e-10 38.8 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CDO75372.1 - 2.1e-06 27.4 0.1 1.6e-05 24.6 0.1 2.3 1 1 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 CDO75372.1 - 0.00025 21.1 0.1 0.00075 19.5 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain OCC1 PF15506.1 CDO75375.1 - 0.72 9.7 0.0 0.72 9.7 0.0 3.0 3 0 0 3 3 3 0 OCC1 family DUF1348 PF07080.6 CDO75376.1 - 1.6e-55 186.8 4.1 1.9e-55 186.5 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 CDO75376.1 - 1.1e-05 25.7 0.3 1.5e-05 25.3 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 CDO75376.1 - 5.4e-05 23.3 0.3 7.9e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 CDO75376.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase RNase_H PF00075.19 CDO75377.1 - 9e-05 22.8 0.0 0.00013 22.3 0.0 1.2 1 0 0 1 1 1 1 RNase H FCSD-flav_bind PF09242.6 CDO75377.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding Zn_clus PF00172.13 CDO75378.1 - 6.3e-09 35.6 8.5 1.3e-08 34.6 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CDO75378.1 - 0.011 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain SNARE PF05739.14 CDO75379.1 - 9.7e-10 37.9 1.0 2.7e-09 36.5 0.7 1.8 1 0 0 1 1 1 1 SNARE domain Polysacc_deac_2 PF04748.8 CDO75379.1 - 0.057 12.4 0.0 0.098 11.6 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Mss4 PF04421.8 CDO75380.1 - 4.7e-10 39.1 0.0 9.5e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 Mss4 protein Acetyltransf_1 PF00583.19 CDO75380.1 - 1.4e-06 28.1 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDO75380.1 - 2.5e-05 24.3 0.0 4.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.20 CDO75381.1 - 3.4e-72 242.7 0.0 4e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75381.1 - 2.1e-33 115.4 0.0 2.8e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CDO75381.1 - 1.5e-12 47.7 2.0 3.5e-12 46.6 1.4 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CDO75381.1 - 0.00095 18.2 0.0 0.0023 16.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CDO75381.1 - 0.033 13.9 0.1 0.06 13.0 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CDO75381.1 - 0.042 12.9 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.22 CDO75383.1 - 2.3e-13 50.0 0.1 2.7e-13 49.7 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO75383.1 - 0.012 14.6 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF503 PF04456.7 CDO75383.1 - 0.04 13.5 0.2 0.062 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF503) Retrotrans_gag PF03732.12 CDO75384.1 - 1.4e-13 50.6 0.0 4.3e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 CDO75384.1 - 0.07 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO75384.1 - 0.36 10.6 0.0 0.82 9.4 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_1 PF00078.22 CDO75385.1 - 6e-17 61.7 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box-like PF12937.2 CDO75386.1 - 0.00023 20.7 0.3 0.00023 20.7 0.2 2.2 3 0 0 3 3 3 1 F-box-like UBN_AB PF14075.1 CDO75386.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Ubinuclein conserved middle domain HET PF06985.6 CDO75387.1 - 6.9e-22 78.0 2.7 6.5e-18 65.2 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ABC_membrane PF00664.18 CDO75388.1 - 7.6e-16 58.3 1.4 7.6e-16 58.3 1.0 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 CDO75388.1 - 7.1e-15 55.5 0.4 3e-14 53.4 0.0 2.3 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CDO75388.1 - 2.6e-08 34.1 1.7 2.5e-05 24.3 0.2 3.4 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 CDO75388.1 - 1.8e-07 31.6 1.8 0.00017 21.9 0.1 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CDO75388.1 - 3.3e-05 23.2 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CDO75388.1 - 0.0038 16.6 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CDO75388.1 - 0.0089 15.5 0.0 0.031 13.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_11 PF13086.1 CDO75388.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CDO75388.1 - 0.035 13.2 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 CDO75388.1 - 0.035 13.5 0.0 0.11 11.9 0.0 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 CDO75388.1 - 0.037 12.9 0.0 0.067 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Adeno_IVa2 PF02456.10 CDO75388.1 - 0.061 11.9 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Dynamin_N PF00350.18 CDO75388.1 - 0.068 12.9 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Dynamin family ATP-synt_G PF04718.10 CDO75390.1 - 6.4e-21 74.9 0.1 1.5e-20 73.7 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Fic PF02661.13 CDO75391.1 - 3.6e-08 33.9 0.1 8.7e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Fic/DOC family SPDY PF03771.11 CDO75391.1 - 0.057 12.9 0.6 0.14 11.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF317) dCMP_cyt_deam_1 PF00383.17 CDO75392.1 - 2.7e-14 52.6 0.2 3.4e-14 52.3 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CDO75392.1 - 1.9e-05 24.6 0.0 0.0033 17.4 0.0 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 CDO75392.1 - 0.033 13.5 1.2 0.33 10.3 0.0 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Pkinase PF00069.20 CDO75393.1 - 1.2e-58 198.3 0.0 6.8e-52 176.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75393.1 - 2.6e-21 75.8 0.0 1.1e-17 63.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CDO75393.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family FA_desaturase PF00487.19 CDO75394.1 - 3.2e-08 33.3 20.8 7e-07 28.9 4.3 3.0 1 1 1 2 2 2 2 Fatty acid desaturase DUF3474 PF11960.3 CDO75394.1 - 0.00069 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) SIR2 PF02146.12 CDO75396.1 - 1.5e-30 106.2 0.0 1.7e-15 57.1 0.0 3.0 3 0 0 3 3 3 2 Sir2 family DUF364 PF04016.7 CDO75396.1 - 0.0071 15.6 0.1 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF364) TPP_enzyme_M PF00205.17 CDO75396.1 - 0.0075 16.0 0.1 2.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain SIR2 PF02146.12 CDO75397.1 - 1.3e-13 51.0 0.0 5.7e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Sir2 family APH PF01636.18 CDO75397.1 - 1.4e-13 51.1 0.0 3.3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO75397.1 - 7.1e-06 25.7 0.0 0.00012 21.7 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.20 CDO75397.1 - 0.00021 20.5 0.0 0.079 12.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain TPP_enzyme_M PF00205.17 CDO75397.1 - 0.0054 16.4 0.1 0.88 9.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Pkinase_Tyr PF07714.12 CDO75397.1 - 0.013 14.5 0.0 0.14 11.1 0.0 2.4 1 1 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.9 CDO75397.1 - 0.037 13.0 0.0 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase Potyvirid-P3 PF13608.1 CDO75397.1 - 0.25 10.4 0.0 0.36 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Dimer_Tnp_hAT PF05699.9 CDO75398.1 - 5.9e-17 61.0 0.0 1.1e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 CDO75398.1 - 0.0014 18.6 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) EFF-AFF PF14884.1 CDO75400.1 - 0.042 11.9 0.0 0.048 11.7 0.0 1.1 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen HET PF06985.6 CDO75401.1 - 3.4e-16 59.6 0.1 3.6e-14 53.0 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RTC4 PF14474.1 CDO75402.1 - 2.3e-08 33.9 0.0 5.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain DUF3123 PF11321.3 CDO75402.1 - 0.044 14.0 0.1 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Transposase_21 PF02992.9 CDO75403.1 - 3.6e-20 72.0 0.0 6.3e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO75403.1 - 2.5e-05 23.7 0.0 5.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Fungal_trans PF04082.13 CDO75404.1 - 1.4e-07 30.6 0.7 2.4e-07 29.8 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain W2 PF02020.13 CDO75405.1 - 4.4e-19 68.2 1.4 2.7e-18 65.6 0.0 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Recombinase PF07508.8 CDO75405.1 - 0.0026 17.9 0.1 0.56 10.4 0.0 2.6 2 0 0 2 2 2 2 Recombinase Pkinase PF00069.20 CDO75407.1 - 1.2e-09 37.7 0.0 1.8e-08 33.8 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75407.1 - 8.1e-05 21.8 0.1 0.00012 21.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Homez PF11569.3 CDO75407.1 - 0.058 12.4 0.2 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez LRRNT PF01462.13 CDO75407.1 - 0.13 11.8 0.3 2.9 7.4 0.1 2.6 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain PP2C PF00481.16 CDO75408.1 - 1.9e-65 220.8 0.2 2.1e-52 178.0 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 CDO75408.1 - 0.00047 19.9 0.1 0.0058 16.3 0.1 2.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Choline_transpo PF04515.7 CDO75409.1 - 1.3e-93 313.4 11.0 1.3e-93 313.4 7.6 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pkinase PF00069.20 CDO75410.1 - 6.8e-09 35.2 0.1 3e-08 33.1 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75410.1 - 0.00015 20.9 0.0 0.00048 19.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDO75411.1 - 1.7e-09 37.1 0.0 9.7e-09 34.7 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75411.1 - 4.7e-06 25.8 0.0 6.7e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO75411.1 - 0.04 13.6 1.0 0.09 12.4 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Mnd1 PF03962.10 CDO75413.1 - 1.7e-17 63.6 3.9 2e-17 63.4 2.7 1.0 1 0 0 1 1 1 1 Mnd1 family DUF4515 PF14988.1 CDO75413.1 - 0.0032 17.1 2.8 0.0038 16.9 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) Snapin_Pallidin PF14712.1 CDO75413.1 - 0.015 15.6 2.2 0.02 15.1 1.5 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Med9 PF07544.8 CDO75413.1 - 0.017 14.8 3.2 0.03 14.0 2.2 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4164 PF13747.1 CDO75413.1 - 0.033 14.3 6.1 0.053 13.6 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Apt1 PF10351.4 CDO75413.1 - 0.034 13.0 2.3 0.036 12.9 1.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain IMD PF08397.6 CDO75413.1 - 0.045 13.0 0.6 0.057 12.7 0.4 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain LemA PF04011.7 CDO75413.1 - 0.057 12.5 1.6 0.076 12.1 0.9 1.3 1 1 0 1 1 1 0 LemA family APG6 PF04111.7 CDO75413.1 - 0.061 12.3 2.5 0.063 12.3 1.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 CDO75413.1 - 0.063 13.0 5.4 0.084 12.6 3.3 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FemAB PF02388.11 CDO75413.1 - 0.2 10.2 1.9 0.21 10.2 1.3 1.1 1 0 0 1 1 1 0 FemAB family IncA PF04156.9 CDO75413.1 - 0.26 10.8 3.2 0.33 10.5 2.2 1.2 1 0 0 1 1 1 0 IncA protein DUF572 PF04502.8 CDO75413.1 - 0.33 10.1 3.4 0.34 10.0 2.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3811 PF11656.3 CDO75413.1 - 0.39 10.8 2.8 0.54 10.3 2.0 1.3 1 0 0 1 1 1 0 YjbD family (DUF3811) DUF2205 PF10224.4 CDO75413.1 - 0.95 9.0 3.7 2.3 7.8 2.6 1.6 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF2802 PF10975.3 CDO75413.1 - 1.1 9.0 5.2 6.3 6.6 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) Val_tRNA-synt_C PF10458.4 CDO75413.1 - 1.2 9.2 5.8 6.1 7.0 0.2 2.6 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm FUSC PF04632.7 CDO75413.1 - 1.2 7.4 5.3 1.3 7.4 3.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.9 CDO75413.1 - 1.3 8.9 8.1 1.6 8.6 5.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.10 CDO75413.1 - 2 7.9 9.5 0.68 9.4 2.3 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.1 CDO75413.1 - 7.2 7.1 8.9 60 4.1 6.0 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 CDO75414.1 - 2.5e-13 50.0 0.2 2.5e-13 50.0 0.1 1.7 2 0 0 2 2 2 1 Mnd1 family APH PF01636.18 CDO75418.1 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RICTOR_M PF14666.1 CDO75419.1 - 1.8e-79 265.9 0.0 1.5e-77 259.6 0.0 3.6 3 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 CDO75419.1 - 8.4e-59 199.0 0.2 2.2e-46 158.1 0.0 2.5 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 CDO75419.1 - 4.6e-34 116.8 0.0 6.2e-33 113.1 0.0 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 CDO75419.1 - 3.5e-31 106.9 0.0 1.8e-28 98.2 0.0 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 CDO75419.1 - 5.8e-09 35.5 1.7 1.6e-08 34.1 1.2 1.7 1 0 0 1 1 1 1 Hr1 repeat HEAT_2 PF13646.1 CDO75419.1 - 4.2e-06 26.9 0.2 0.0021 18.3 0.0 3.9 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 CDO75419.1 - 0.0047 16.8 0.0 0.61 10.3 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 CDO75419.1 - 0.0048 17.3 0.1 1.5 9.4 0.0 3.7 3 0 0 3 3 3 1 HEAT-like repeat Oxidored_FMN PF00724.15 CDO75420.1 - 6e-67 226.0 0.0 2.3e-66 224.1 0.0 1.7 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2090 PF09863.4 CDO75420.1 - 0.05 12.4 0.0 0.16 10.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2090) F-box-like PF12937.2 CDO75421.1 - 0.0042 16.7 0.1 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Sod_Cu PF00080.15 CDO75422.1 - 1.3e-30 106.4 0.0 1.7e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Motile_Sperm PF00635.21 CDO75424.1 - 3e-27 94.4 0.3 5.5e-27 93.5 0.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.3 CDO75424.1 - 0.0011 19.0 0.0 0.0033 17.5 0.0 1.8 1 1 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Spc42p PF11544.3 CDO75424.1 - 0.009 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Spindle pole body component Spc42p DUF605 PF04652.11 CDO75424.1 - 6.1 6.1 15.9 8.4 5.6 11.0 1.2 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 CDO75425.1 - 1.6e-68 230.6 0.0 2.1e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75425.1 - 7.5e-30 103.8 0.0 1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CDO75425.1 - 2.2e-10 40.8 1.5 5.2e-10 39.6 1.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CDO75425.1 - 3.6e-05 22.8 0.0 6.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDO75425.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDO75425.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family G-patch PF01585.18 CDO75426.1 - 6.1e-08 32.3 0.0 1.3e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CDO75426.1 - 0.054 13.3 2.8 1.5 8.7 0.2 3.3 3 0 0 3 3 3 0 DExH-box splicing factor binding site DUF837 PF05769.6 CDO75427.1 - 0.011 15.2 13.6 0.073 12.5 5.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF837) Nsp1_C PF05064.8 CDO75427.1 - 0.014 15.0 1.8 0.021 14.4 0.2 2.0 2 0 0 2 2 2 0 Nsp1-like C-terminal region IgaA PF07095.6 CDO75427.1 - 0.062 11.0 0.3 0.11 10.2 0.1 1.5 1 1 0 1 1 1 0 Intracellular growth attenuator protein IgaA HALZ PF02183.13 CDO75427.1 - 0.3 10.8 10.3 0.26 11.0 0.3 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 CDO75427.1 - 0.37 10.5 7.9 0.82 9.4 0.7 2.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain F-box-like PF12937.2 CDO75428.1 - 1e-11 44.3 0.0 3.2e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like Band_7 PF01145.20 CDO75429.1 - 4.2e-14 52.8 0.8 6.3e-14 52.2 0.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family MutS_III PF05192.13 CDO75430.1 - 8.8e-27 94.2 0.0 1.6e-26 93.3 0.0 1.4 1 1 0 1 1 1 1 MutS domain III MutS_V PF00488.16 CDO75430.1 - 1.2e-09 37.9 0.1 1.6e-08 34.2 0.0 2.7 2 1 0 2 2 2 1 MutS domain V MutS_IV PF05190.13 CDO75430.1 - 0.044 13.9 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 MutS family domain IV AAA_14 PF13173.1 CDO75430.1 - 0.17 11.8 0.0 0.88 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Exo_endo_phos_2 PF14529.1 CDO75431.1 - 2e-08 33.8 0.0 4.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC_6 PF15288.1 CDO75431.1 - 0.014 15.0 1.4 0.035 13.7 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle ERM PF00769.14 CDO75431.1 - 0.014 14.9 1.5 0.026 14.0 1.0 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Laminin_II PF06009.7 CDO75431.1 - 0.09 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Laminin Domain II Occludin_ELL PF07303.8 CDO75432.1 - 0.13 12.9 8.0 2.1 9.1 1.0 2.7 2 1 1 3 3 3 0 Occludin homology domain DUF3584 PF12128.3 CDO75432.1 - 0.56 7.4 21.8 0.77 7.0 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CCDC144C PF14915.1 CDO75432.1 - 0.83 8.5 22.6 6.3 5.6 13.0 2.5 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region BLOC1_2 PF10046.4 CDO75432.1 - 0.9 9.7 7.3 9.5 6.4 0.0 2.9 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2205 PF10224.4 CDO75432.1 - 0.96 9.0 10.0 0.48 10.0 0.5 3.0 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) Phage_GP20 PF06810.6 CDO75432.1 - 3.5 7.0 10.6 3.3 7.1 2.4 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Apolipoprotein PF01442.13 CDO75433.1 - 0.082 12.4 10.0 0.88 9.0 0.5 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DNA_topoisoIV PF00521.15 CDO75433.1 - 0.15 10.8 1.6 0.21 10.3 1.1 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A FdhE PF04216.7 CDO75433.1 - 1 9.0 5.8 1.2 8.7 1.6 2.0 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation tRNA-synt_1 PF00133.17 CDO75434.1 - 9.6e-137 456.5 0.0 1.3e-136 456.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CDO75434.1 - 2.1e-17 62.8 0.0 8e-10 37.9 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CDO75434.1 - 6.8e-09 35.6 0.3 3.5e-08 33.3 0.1 2.3 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CDO75434.1 - 0.011 14.8 0.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain 7tm_7 PF08395.7 CDO75434.1 - 0.46 9.4 0.0 0.77 8.7 0.0 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor Cyclin_N PF00134.18 CDO75435.1 - 1.7e-45 153.6 0.7 6.2e-45 151.8 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CDO75435.1 - 1.7e-26 92.4 0.0 3.6e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain ProRS-C_1 PF09180.6 CDO75436.1 - 1.5e-25 88.8 2.2 3.3e-25 87.7 1.6 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 CDO75436.1 - 1.3e-21 76.9 0.1 2.1e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.10 CDO75436.1 - 1.4e-13 50.8 0.0 2.7e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.15 CDO75436.1 - 1.9e-08 34.0 0.0 4.8e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain TraC_F_IV PF11130.3 CDO75436.1 - 0.022 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Oxysterol_BP PF01237.13 CDO75437.1 - 4.1e-50 170.2 0.0 5e-36 123.9 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein PIGA PF08288.7 CDO75438.1 - 2.3e-38 130.4 0.4 6e-38 129.1 0.1 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CDO75438.1 - 4.6e-24 84.7 0.0 7.3e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CDO75438.1 - 2e-12 47.3 0.0 5.8e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CDO75438.1 - 8.9e-12 45.4 0.6 1.5e-11 44.7 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CDO75438.1 - 7.4e-11 42.0 1.1 1.6e-10 41.0 0.3 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 CDO75438.1 - 0.0005 20.2 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Transp_cyt_pur PF02133.10 CDO75439.1 - 8.6e-32 110.2 38.3 2e-30 105.7 26.5 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Carboxyl_trans PF01039.17 CDO75440.1 - 4.9e-51 173.6 0.0 1.2e-49 169.0 0.0 2.1 2 0 0 2 2 2 2 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CDO75441.1 - 3.5e-47 160.4 0.0 5.8e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 CDO75441.1 - 2.5e-26 91.7 0.0 6.5e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CDO75441.1 - 7.8e-19 68.1 0.1 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CDO75441.1 - 3.4e-15 55.6 0.0 2.2e-09 36.5 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CDO75441.1 - 1.1e-09 37.7 0.9 3.5e-09 36.1 0.4 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme CPSase_L_chain PF00289.17 CDO75441.1 - 1.3e-09 38.1 0.2 3.5e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain RimK PF08443.6 CDO75441.1 - 2.1e-05 24.0 0.0 0.00041 19.8 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 CDO75441.1 - 2.2e-05 23.9 0.0 4.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CDO75441.1 - 0.00034 20.2 0.1 0.14 11.7 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 CDO75441.1 - 0.00043 19.6 0.0 0.00077 18.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CDO75441.1 - 0.012 15.4 0.0 0.058 13.2 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp domain GCV_H PF01597.14 CDO75441.1 - 0.024 14.3 0.4 1.1 8.9 0.1 2.8 2 1 1 3 3 3 0 Glycine cleavage H-protein ATP-grasp_2 PF08442.5 CDO75441.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain DER1 PF04511.10 CDO75442.1 - 1.7e-32 112.5 0.4 2.1e-32 112.2 0.3 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 CDO75442.1 - 0.0077 16.2 7.0 0.019 15.0 4.9 1.6 1 1 0 1 1 1 1 Rhomboid family Pribosyltran PF00156.22 CDO75443.1 - 1.2e-15 57.3 0.4 1.9e-15 56.6 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Transposase_21 PF02992.9 CDO75446.1 - 2.6e-16 59.3 0.0 5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DDE_3 PF13358.1 CDO75448.1 - 3.4e-13 49.5 0.0 3e-12 46.5 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Syja_N PF02383.13 CDO75449.1 - 7.2e-89 297.6 0.0 1.1e-88 297.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain zf-C2H2 PF00096.21 CDO75450.1 - 1.6e-09 37.5 16.9 0.011 16.0 1.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO75450.1 - 5.9e-06 26.2 16.8 0.1 12.9 1.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CDO75450.1 - 0.00018 21.6 12.6 0.0011 19.0 2.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain ATPase-cat_bd PF12156.3 CDO75450.1 - 0.15 12.6 0.6 0.47 11.0 0.5 1.8 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase zf-DNA_Pol PF08996.5 CDO75450.1 - 0.22 10.8 0.3 0.46 9.7 0.2 1.5 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Zn_Tnp_IS1595 PF12760.2 CDO75450.1 - 0.95 9.3 6.4 0.99 9.2 3.2 1.9 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-BED PF02892.10 CDO75450.1 - 1.2 8.8 6.5 8.5 6.2 1.5 2.4 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 CDO75450.1 - 5.8 7.1 7.4 45 4.3 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Pyr_redox_dim PF02852.17 CDO75451.1 - 3.6e-42 142.8 1.9 6.7e-42 141.9 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CDO75451.1 - 1.6e-39 135.8 17.7 1.9e-37 129.1 12.3 3.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO75451.1 - 4e-22 78.4 7.1 2.7e-19 69.3 0.7 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CDO75451.1 - 6.3e-12 45.0 4.4 2.3e-10 39.9 0.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 CDO75451.1 - 1.1e-11 44.5 11.8 7.3e-11 41.7 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CDO75451.1 - 3.9e-10 40.1 0.6 3.5e-06 27.2 0.2 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO75451.1 - 2.3e-08 33.9 5.5 4.8e-05 23.3 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CDO75451.1 - 9.8e-08 30.8 12.9 0.00025 19.6 0.6 4.1 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 CDO75451.1 - 2.2e-07 30.1 0.3 0.0052 15.7 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 CDO75451.1 - 5.2e-07 28.9 17.5 0.01 14.7 0.1 3.7 2 2 1 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDO75451.1 - 8.7e-07 28.1 2.3 8.7e-07 28.1 1.6 4.4 3 1 2 5 5 5 1 FAD binding domain Thi4 PF01946.12 CDO75451.1 - 5.7e-05 22.3 5.1 0.00099 18.2 0.0 2.5 2 1 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 CDO75451.1 - 0.00021 20.8 1.6 0.031 13.8 0.1 2.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 CDO75451.1 - 0.00023 20.3 10.1 0.037 13.0 0.4 3.4 3 1 0 3 3 3 2 FAD binding domain THF_DHG_CYH_C PF02882.14 CDO75451.1 - 0.024 13.6 1.6 0.043 12.8 0.0 2.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.7 CDO75451.1 - 0.62 8.9 7.8 1 8.2 0.3 3.1 3 1 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 CDO75451.1 - 4 7.0 6.8 0.28 10.8 0.3 2.3 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lon_C PF05362.8 CDO75452.1 - 1.5e-65 220.3 0.2 2.6e-65 219.5 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CDO75452.1 - 5e-23 81.7 0.0 1.1e-22 80.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDO75452.1 - 7.5e-10 38.6 0.0 2.1e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON PF02190.11 CDO75452.1 - 5.6e-09 35.9 0.0 1.9e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 CDO75452.1 - 9.3e-06 25.1 0.0 4.5e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 CDO75452.1 - 1.3e-05 25.1 0.0 4.9e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CDO75452.1 - 0.0001 22.3 0.0 0.0001 22.3 0.0 3.2 3 1 1 4 4 4 1 AAA ATPase domain AAA_19 PF13245.1 CDO75452.1 - 0.00094 18.8 1.4 0.0031 17.2 0.1 2.6 3 0 0 3 3 2 1 Part of AAA domain AAA_33 PF13671.1 CDO75452.1 - 0.00097 19.0 0.2 0.01 15.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CDO75452.1 - 0.0013 18.8 1.7 0.08 13.0 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 CDO75452.1 - 0.0038 18.0 0.0 0.017 15.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CDO75452.1 - 0.0039 16.2 0.0 0.068 12.2 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Allexi_40kDa PF05549.6 CDO75452.1 - 0.012 14.8 1.0 1.2 8.4 0.2 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein AAA_3 PF07726.6 CDO75452.1 - 0.019 14.6 0.0 0.049 13.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CDO75452.1 - 0.025 14.0 0.0 0.086 12.2 0.0 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 CDO75452.1 - 0.041 13.2 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CDO75452.1 - 0.045 12.4 0.0 0.19 10.3 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus MobB PF03205.9 CDO75452.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_11 PF13086.1 CDO75452.1 - 0.089 12.3 1.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CDO75452.1 - 0.092 12.9 0.0 0.31 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF3138 PF11336.3 CDO75452.1 - 2.5 6.1 3.3 5.2 5.1 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Tubulin_3 PF14881.1 CDO75453.1 - 1.9e-21 76.3 0.0 3.3e-10 39.7 0.1 2.3 1 1 1 2 2 2 2 Tubulin domain Misat_Tub_SegII PF10644.4 CDO75453.1 - 3.3e-16 59.3 0.6 7.1e-16 58.3 0.3 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain DUF89 PF01937.14 CDO75454.1 - 1e-94 317.2 0.1 2.6e-48 164.6 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function DUF89 VHS PF00790.14 CDO75455.1 - 4.7e-14 52.2 0.0 8.8e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 CDO75455.1 - 8.2e-07 28.9 0.2 0.013 15.4 0.0 2.4 2 0 0 2 2 2 2 GAT domain DUF1777 PF08648.7 CDO75455.1 - 0.00016 21.4 22.3 0.00016 21.4 15.5 4.1 3 1 0 3 3 3 1 Protein of unknown function (DUF1777) DUF1294 PF06961.8 CDO75455.1 - 0.044 13.7 0.1 0.044 13.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) Glyco_hydro_3 PF00933.16 CDO75456.1 - 7.7e-68 228.6 0.1 1.2e-67 228.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain RRM_1 PF00076.17 CDO75457.1 - 3e-12 45.9 0.1 4.5e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO75457.1 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO75457.1 - 5.1e-07 29.4 0.0 7.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT_2 PF13646.1 CDO75458.1 - 2.6e-11 43.6 13.7 0.19 12.0 0.0 8.0 6 2 1 7 7 7 5 HEAT repeats HEAT PF02985.17 CDO75458.1 - 1e-05 25.2 15.9 1.2 9.4 0.0 9.0 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 CDO75458.1 - 0.00019 21.8 18.3 0.0049 17.3 0.1 8.9 8 1 0 8 8 8 1 HEAT-like repeat Arm PF00514.18 CDO75458.1 - 0.008 15.9 1.2 0.097 12.5 0.1 3.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat UME PF08064.8 CDO75458.1 - 0.19 11.6 0.9 1.5e+02 2.3 0.0 4.6 4 1 1 5 5 5 0 UME (NUC010) domain PAP_assoc PF03828.14 CDO75459.1 - 1.9e-17 62.9 0.1 3.5e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CDO75459.1 - 8.5e-05 22.8 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain XPG_I PF00867.13 CDO75460.1 - 4.7e-21 74.6 0.0 1.4e-20 73.1 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 CDO75460.1 - 6.1e-05 23.2 0.0 0.00017 21.8 0.0 1.7 1 1 0 1 1 1 1 XPG N-terminal domain Menin PF05053.8 CDO75460.1 - 1.6 6.7 4.4 3 5.9 3.0 1.3 1 0 0 1 1 1 0 Menin Rap_GAP PF02145.10 CDO75461.1 - 1.5e-44 151.6 0.0 2.5e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 CDO75461.1 - 5.4e-26 91.5 1.0 8.4e-25 87.5 0.2 2.2 2 0 0 2 2 2 1 Tuberin DUF3384 PF11864.3 CDO75461.1 - 0.017 13.6 0.0 0.48 8.8 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3384) DNA_gyraseB PF00204.20 CDO75461.1 - 0.54 9.4 0.0 1.4 8.1 0.0 1.6 1 0 0 1 1 1 0 DNA gyrase B Cluap1 PF10234.4 CDO75462.1 - 0.012 14.8 4.7 0.014 14.6 3.3 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Lipase_chap PF03280.9 CDO75462.1 - 0.03 13.8 5.0 0.038 13.5 3.4 1.2 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Vmethyltransf_C PF08456.5 CDO75462.1 - 0.14 11.5 2.8 0.097 12.0 0.7 1.6 1 1 1 2 2 2 0 Viral methyltransferase C-terminal FlxA PF14282.1 CDO75462.1 - 0.25 11.3 0.2 0.25 11.3 0.1 2.0 2 0 0 2 2 2 0 FlxA-like protein GvpL_GvpF PF06386.6 CDO75462.1 - 0.71 9.4 4.8 0.28 10.7 1.1 1.7 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF TMF_DNA_bd PF12329.3 CDO75462.1 - 2.1 8.2 9.2 0.22 11.3 1.8 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 CDO75462.1 - 2.2 8.2 12.4 0.14 12.1 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FliJ PF02050.11 CDO75462.1 - 3.6 7.6 14.1 57 3.7 9.8 2.2 1 1 0 1 1 1 0 Flagellar FliJ protein SUI1 PF01253.17 CDO75463.1 - 1.4e-05 24.8 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 RNase_H PF00075.19 CDO75464.1 - 1.1e-07 32.1 0.0 1.8e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO75464.1 - 0.0015 18.8 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase U3_assoc_6 PF08640.6 CDO75468.1 - 0.072 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 TFIIA PF03153.8 CDO75468.1 - 5.3 6.8 13.1 8.4 6.1 9.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 CDO75468.1 - 5.4 4.7 13.2 7.7 4.2 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family Helicase_C PF00271.26 CDO75469.1 - 1.8e-17 62.9 0.0 3.8e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO75469.1 - 1.7e-16 60.1 0.0 5.8e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 CDO75469.1 - 0.032 13.0 0.0 0.051 12.3 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 CDO75469.1 - 0.1 12.4 0.0 0.32 10.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NAD_binding_6 PF08030.7 CDO75470.1 - 6.3e-26 91.1 0.0 1.2e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CDO75470.1 - 3.6e-21 75.0 0.0 7.4e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 CDO75470.1 - 3e-14 53.1 12.2 3e-14 53.1 8.5 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 CDO75470.1 - 0.0011 19.4 0.0 0.16 12.5 0.0 2.3 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CDO75470.1 - 0.003 17.6 0.0 0.0095 16.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain HORMA PF02301.13 CDO75471.1 - 8.4e-37 126.6 0.0 9.7e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 CDO75471.1 - 0.00096 18.6 0.1 0.0062 15.9 0.0 1.9 2 0 0 2 2 2 1 Autophagy-related protein 13 Ribonucleas_3_3 PF14622.1 CDO75472.1 - 1.1e-08 35.1 0.0 4.4e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CDO75472.1 - 1.5e-07 31.8 0.0 1.4e-06 28.6 0.0 2.3 1 1 0 1 1 1 1 Ribonuclease III domain CAF1A PF12253.3 CDO75472.1 - 0.013 15.6 1.0 0.14 12.2 0.1 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A SKN1 PF03935.10 CDO75475.1 - 2.5e-192 639.5 0.2 2.9e-192 639.2 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 CDO75475.1 - 5.1e-08 32.4 0.5 4.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 SKN1 PF03935.10 CDO75476.1 - 1.1e-188 627.5 0.7 1.3e-188 627.2 0.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF221 PF02714.10 CDO75477.1 - 1.7e-13 50.1 14.9 5.9e-13 48.3 10.8 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CDO75477.1 - 0.00012 21.7 0.3 0.00012 21.7 0.2 3.3 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CDO75477.1 - 0.0012 18.7 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 CDO75477.1 - 0.0015 19.0 0.0 0.0039 17.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3112 PF11309.3 CDO75477.1 - 0.41 10.4 8.4 0.37 10.5 3.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Sec1 PF00995.18 CDO75478.1 - 2.3e-144 482.1 0.0 2.6e-144 481.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Dala_Dala_lig_N PF01820.16 CDO75478.1 - 0.024 14.9 0.0 0.073 13.3 0.0 1.8 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Bax1-I PF01027.15 CDO75479.1 - 9.5e-36 123.3 7.3 9.5e-36 123.3 5.0 1.6 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.27 CDO75480.1 - 5.7e-53 175.0 19.5 4.9e-10 38.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat LisH PF08513.6 CDO75480.1 - 1.8e-05 24.2 0.0 3.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 CDO75480.1 - 2.6e-05 24.0 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CDO75480.1 - 0.0012 17.9 0.1 0.39 9.7 0.0 2.8 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 CDO75480.1 - 0.0065 14.6 1.2 0.1 10.7 0.2 2.9 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CDO75480.1 - 0.012 14.4 0.0 0.087 11.5 0.0 2.3 2 1 1 3 3 3 0 Nup133 N terminal like WD40 PF00400.27 CDO75481.1 - 1.8e-09 37.0 3.8 0.0014 18.3 0.0 4.1 3 1 0 3 3 3 2 WD domain, G-beta repeat RicinB_lectin_2 PF14200.1 CDO75481.1 - 0.00032 21.0 0.0 0.002 18.4 0.0 2.4 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 CDO75481.1 - 0.022 14.7 0.0 0.8 9.7 0.0 2.6 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain Arginase PF00491.16 CDO75482.1 - 1e-84 284.1 0.2 1.4e-84 283.7 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 CDO75482.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain SUR7 PF06687.7 CDO75483.1 - 2e-17 63.4 14.7 2.8e-17 63.0 10.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CDO75483.1 - 0.00015 21.5 10.2 0.00015 21.5 7.0 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Acetyltransf_3 PF13302.1 CDO75484.1 - 0.00096 19.3 0.0 0.0012 18.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CDO75485.1 - 9.5e-21 74.4 0.0 1.5e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CDO75485.1 - 1.7e-08 34.5 0.1 1.7e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO75485.1 - 4.6e-08 32.9 0.0 7.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 CDO75485.1 - 0.0014 18.5 0.0 0.0039 17.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDO75485.1 - 0.053 13.6 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CDO75485.1 - 0.066 13.3 0.0 0.14 12.3 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GTP_EFTU PF00009.22 CDO75486.1 - 1.2e-62 210.6 0.3 1.9e-62 210.0 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CDO75486.1 - 4.3e-39 132.7 0.0 1.6e-38 130.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CDO75486.1 - 7.6e-21 73.7 0.0 1.7e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CDO75486.1 - 1.6e-13 50.2 0.0 4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CDO75486.1 - 5.5e-13 48.8 0.0 6.1e-12 45.4 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CDO75486.1 - 6.9e-06 25.9 0.2 1.7e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CDO75486.1 - 0.049 13.1 0.5 0.2 11.1 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CDO75486.1 - 0.079 13.4 0.2 0.17 12.3 0.2 1.6 1 0 0 1 1 1 0 Miro-like protein PI-PLC-X PF00388.14 CDO75487.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain AT_hook PF02178.14 CDO75488.1 - 9.6 6.2 12.0 0.13 12.0 2.5 2.4 2 0 0 2 2 2 0 AT hook motif Utp11 PF03998.8 CDO75489.1 - 1.5e-58 198.5 35.9 6.6e-58 196.3 24.9 1.9 1 1 0 1 1 1 1 Utp11 protein Flu_NS2 PF00601.14 CDO75489.1 - 0.051 13.7 0.2 0.19 11.9 0.1 2.1 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) His_kinase PF06580.8 CDO75489.1 - 0.32 10.9 2.0 0.46 10.4 0.1 2.1 2 0 0 2 2 2 0 Histidine kinase VHS PF00790.14 CDO75490.1 - 1.1e-19 70.4 0.0 2.4e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 CDO75490.1 - 7.2e-07 29.1 2.9 1.5e-06 28.0 2.0 1.5 1 0 0 1 1 1 1 GAT domain MAS20 PF02064.10 CDO75490.1 - 0.42 10.5 9.1 1.1 9.2 6.3 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor Fes1 PF08609.5 CDO75490.1 - 0.6 10.6 6.5 1.7 9.1 4.4 1.9 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 Gemini_coat PF00844.13 CDO75490.1 - 2.4 7.3 5.8 4.5 6.4 4.0 1.3 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family Herpes_DNAp_acc PF04929.7 CDO75490.1 - 2.5 7.0 8.4 4.9 6.0 5.8 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TT_ORF1 PF02956.9 CDO75490.1 - 4.5 5.5 9.0 7.2 4.9 6.2 1.2 1 0 0 1 1 1 0 TT viral orf 1 Ycf1 PF05758.7 CDO75490.1 - 4.8 4.7 10.9 6.6 4.3 7.6 1.1 1 0 0 1 1 1 0 Ycf1 U79_P34 PF03064.11 CDO75490.1 - 8 5.8 14.7 0.46 9.9 5.8 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 p450 PF00067.17 CDO75491.1 - 1.6e-24 86.3 0.0 2.5e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2b PF00587.20 CDO75491.1 - 1.1e-11 44.6 0.0 2.7e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CDO75491.1 - 2.7e-07 30.5 0.5 5.1e-07 29.6 0.3 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DNA_pol3_delta2 PF13177.1 CDO75492.1 - 3.8e-12 46.1 0.1 3.2e-10 39.8 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CDO75492.1 - 2e-11 44.1 0.1 3.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CDO75492.1 - 2.4e-09 37.0 0.0 7.4e-09 35.4 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA_14 PF13173.1 CDO75492.1 - 7.5e-08 32.3 0.0 1.5e-07 31.3 0.0 1.5 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 CDO75492.1 - 2.3e-07 29.9 0.1 0.0018 17.0 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CDO75492.1 - 4.3e-07 30.0 0.0 1.1e-05 25.5 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CDO75492.1 - 1.1e-06 28.8 0.1 0.0023 18.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 CDO75492.1 - 1.4e-06 27.5 0.0 4.3e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 CDO75492.1 - 1.6e-05 24.5 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CDO75492.1 - 5.8e-05 22.7 0.0 9.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 CDO75492.1 - 0.00021 20.8 0.1 0.14 11.5 0.0 2.6 2 1 1 3 3 3 2 AAA-like domain Mg_chelatase PF01078.16 CDO75492.1 - 0.00057 19.1 0.0 0.0076 15.4 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 CDO75492.1 - 0.0016 18.1 0.3 0.0078 15.9 0.1 2.0 1 1 1 2 2 2 1 NTPase ArgK PF03308.11 CDO75492.1 - 0.0017 17.1 0.0 0.0054 15.5 0.0 1.8 1 1 0 1 1 1 1 ArgK protein AAA_19 PF13245.1 CDO75492.1 - 0.0044 16.7 0.0 0.0095 15.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CDO75492.1 - 0.0064 16.0 0.0 0.0083 15.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 CDO75492.1 - 0.0068 15.9 0.1 0.0097 15.4 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_18 PF13238.1 CDO75492.1 - 0.0079 16.5 0.1 0.014 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CDO75492.1 - 0.03 13.7 0.0 0.068 12.6 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family DEAD PF00270.24 CDO75492.1 - 0.045 13.2 0.1 0.98 8.8 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 CDO75492.1 - 0.062 13.4 0.1 0.21 11.7 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_31 PF13614.1 CDO75492.1 - 0.066 13.1 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 CDO75492.1 - 0.071 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 CDO75492.1 - 0.094 13.5 0.6 0.24 12.2 0.4 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CDO75492.1 - 0.096 12.9 0.1 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 CDO75492.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ParA PF10609.4 CDO75493.1 - 2e-32 110.8 0.1 3.2e-32 110.2 0.1 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CDO75493.1 - 1e-13 51.1 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CDO75493.1 - 1.8e-06 27.9 0.0 5.5e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CDO75493.1 - 7.6e-06 25.1 0.0 4.6e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 CDO75493.1 - 1.8e-05 23.9 0.5 0.00076 18.6 0.2 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_22 PF13401.1 CDO75493.1 - 0.086 12.9 0.1 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain YhjQ PF06564.7 CDO75493.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.4 1 1 0 1 1 1 0 YhjQ protein DUF258 PF03193.11 CDO75493.1 - 0.18 11.0 0.1 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Syndecan PF01034.15 CDO75495.1 - 0.024 14.2 0.4 0.048 13.3 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain RSN1_TM PF13967.1 CDO75495.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport RRM_1 PF00076.17 CDO75497.1 - 3e-09 36.3 0.0 0.0029 17.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO75497.1 - 6.9e-08 32.3 0.0 0.0053 16.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO75497.1 - 0.0011 18.8 0.0 0.76 9.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb6 PF01192.17 CDO75498.1 - 1.4e-21 75.9 0.1 1.9e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 SIR2 PF02146.12 CDO75499.1 - 1.9e-26 92.9 0.0 4.3e-24 85.2 0.0 2.2 1 1 0 1 1 1 1 Sir2 family Methyltransf_12 PF08242.7 CDO75500.1 - 0.018 15.5 0.0 0.05 14.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ribonuclease_T2 PF00445.13 CDO75501.1 - 1.9e-26 92.8 0.0 3.1e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Myb_DNA-binding PF00249.26 CDO75502.1 - 1.2e-08 34.8 0.0 4.8e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO75502.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SURF1 PF02104.10 CDO75504.1 - 1.3e-55 188.4 0.2 1.6e-55 188.2 0.1 1.0 1 0 0 1 1 1 1 SURF1 family ANTH PF07651.11 CDO75505.1 - 1.3e-71 240.5 0.0 1.3e-71 240.5 0.0 3.4 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.12 CDO75505.1 - 1e-62 210.5 7.8 1e-62 210.5 5.4 4.2 4 2 0 4 4 4 1 I/LWEQ domain Reo_sigmaC PF04582.7 CDO75505.1 - 1 8.4 13.0 1.2 8.2 1.0 2.9 1 1 0 2 2 2 0 Reovirus sigma C capsid protein SIR2 PF02146.12 CDO75507.1 - 3e-12 46.6 0.0 1.3e-07 31.5 0.0 2.4 2 1 0 2 2 2 2 Sir2 family DUF1192 PF06698.6 CDO75507.1 - 0.021 14.6 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) TPP_enzyme_M PF00205.17 CDO75507.1 - 0.026 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Ion_trans PF00520.26 CDO75508.1 - 3.2e-06 26.5 2.6 3.2e-06 26.5 1.8 1.7 2 0 0 2 2 2 1 Ion transport protein CWC25 PF12542.3 CDO75509.1 - 1.2e-24 86.5 1.4 1.2e-24 86.5 1.0 4.0 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 CDO75509.1 - 4.8e-13 48.8 13.5 4.8e-13 48.8 9.4 4.8 3 2 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR MFS_1 PF07690.11 CDO75510.1 - 1.1e-45 155.9 34.7 1.4e-43 148.9 13.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO75510.1 - 9.6e-11 40.9 5.6 9.6e-11 40.9 3.9 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CDO75510.1 - 1.2e-06 27.0 4.3 1.2e-06 27.0 3.0 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 CDO75510.1 - 1e-05 24.1 4.0 1e-05 24.1 2.8 3.5 3 1 1 4 4 4 1 MFS/sugar transport protein ATG22 PF11700.3 CDO75510.1 - 0.00046 18.8 2.4 0.00046 18.8 1.7 3.2 3 1 1 4 4 4 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 CDO75510.1 - 0.0061 16.3 0.1 0.0061 16.3 0.0 3.7 4 2 1 5 5 5 1 MFS_1 like family DUF515 PF04415.7 CDO75510.1 - 9.5 4.3 8.1 13 3.8 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Fungal_trans PF04082.13 CDO75511.1 - 6.4e-31 107.1 0.1 6e-30 103.9 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CDO75511.1 - 1.3e-06 28.1 10.4 2.5e-06 27.2 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HORMA PF02301.13 CDO75512.1 - 2.5e-08 33.6 0.0 3.2e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 HORMA domain PX PF00787.19 CDO75513.1 - 4.5e-21 74.7 0.7 2.8e-20 72.1 0.6 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 CDO75513.1 - 2.2e-05 23.8 6.7 0.00013 21.2 3.2 2.8 3 1 0 3 3 3 1 Vps5 C terminal like Lung_7-TM_R PF06814.8 CDO75514.1 - 1.2e-49 168.8 13.0 1.6e-49 168.4 9.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor RNA_pol_Rpb2_6 PF00562.23 CDO75515.1 - 6.6e-130 433.3 0.2 1.1e-129 432.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CDO75515.1 - 2.6e-68 228.9 0.0 4e-68 228.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CDO75515.1 - 7e-48 162.5 0.1 1.5e-47 161.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CDO75515.1 - 3.2e-29 101.0 0.0 7.2e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CDO75515.1 - 9.3e-28 95.8 0.7 2.3e-27 94.5 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 CDO75515.1 - 1.5e-23 82.5 0.4 3.2e-23 81.4 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 CDO75515.1 - 2.1e-23 81.8 0.1 4.6e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 MHC_II_alpha PF00993.15 CDO75515.1 - 0.045 13.3 0.3 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 Class II histocompatibility antigen, alpha domain Zn_Tnp_IS1595 PF12760.2 CDO75515.1 - 0.13 12.0 0.2 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Glyco_hydro_7 PF00840.15 CDO75516.1 - 4.9e-209 694.0 21.4 5.6e-209 693.9 14.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fructosamin_kin PF03881.9 CDO75517.1 - 4e-56 190.1 0.0 5.1e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 CDO75517.1 - 6.2e-08 32.6 0.0 7.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 CDO75517.1 - 0.16 10.5 0.5 1.9 7.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) Oxidored_FMN PF00724.15 CDO75518.1 - 6.7e-63 212.7 0.0 9.9e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RAMPs PF03787.10 CDO75518.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 RAMP superfamily PulG PF11773.3 CDO75521.1 - 0.091 12.4 0.9 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin Fe-ADH PF00465.14 CDO75522.1 - 9.6e-18 63.9 0.3 1.3e-17 63.5 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CDO75522.1 - 1.2e-05 24.7 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase NUC129 PF08157.6 CDO75522.1 - 0.048 13.5 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 NUC129 domain EF-hand_6 PF13405.1 CDO75523.1 - 0.049 13.5 0.4 0.53 10.3 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain Fe-ADH PF00465.14 CDO75524.1 - 6.5e-66 222.4 0.0 8.6e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CDO75524.1 - 3.1e-16 59.4 0.0 6e-16 58.5 0.0 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Lactamase_B PF00753.22 CDO75525.1 - 2.7e-11 43.4 2.4 5.3e-11 42.5 1.6 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CDO75525.1 - 6.8e-06 25.7 0.5 1.1e-05 25.0 0.3 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HCMV_UL139 PF12507.3 CDO75528.1 - 0.012 15.7 1.2 0.041 14.0 0.0 2.0 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Spore_III_AF PF09581.5 CDO75528.1 - 0.077 12.8 0.2 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Med14 PF08638.6 CDO75529.1 - 7.1e-46 155.9 0.0 1.6e-45 154.7 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 HEAT PF02985.17 CDO75531.1 - 1.3e-05 24.8 0.1 5.3 7.3 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat Pkinase PF00069.20 CDO75531.1 - 0.0048 16.0 0.0 0.0093 15.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75531.1 - 0.044 12.8 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Zn_clus PF00172.13 CDO75532.1 - 0.047 13.6 2.0 0.073 12.9 1.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 CDO75535.1 - 1.1e-50 172.2 0.0 1e-44 152.6 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CDO75535.1 - 1e-12 48.8 0.1 2.5e-12 47.5 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 CDO75536.1 - 1e-87 294.2 0.0 1.3e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CDO75536.1 - 7.6e-12 46.0 0.9 2.6e-11 44.2 0.0 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 CDO75537.1 - 1.1e-79 267.8 0.0 1.4e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CDO75537.1 - 5.7e-14 52.8 0.2 1.7e-13 51.3 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 CDO75538.1 - 6.8e-73 245.4 0.0 4.3e-72 242.8 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CDO75538.1 - 1.4e-12 48.4 0.2 8.1e-12 45.9 0.1 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribonuc_2-5A PF06479.7 CDO75539.1 - 3.9e-45 152.8 0.1 6.2e-45 152.1 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 CDO75539.1 - 3.3e-39 134.5 0.0 4.6e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75539.1 - 6.8e-18 64.6 0.0 1.9e-17 63.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 CDO75539.1 - 0.0049 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 CDO75539.1 - 0.0049 16.3 0.0 0.02 14.4 0.0 2.2 1 0 0 1 1 1 1 PQQ enzyme repeat Kdo PF06293.9 CDO75539.1 - 0.16 10.9 0.1 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cupin_1 PF00190.17 CDO75540.1 - 5.2e-29 100.5 0.0 1.1e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 CDO75540.1 - 3.4e-27 93.7 0.5 4.5e-14 51.6 0.1 3.3 3 0 0 3 3 3 3 Cupin domain Cupin_3 PF05899.7 CDO75540.1 - 1.1e-09 37.5 0.0 0.00055 19.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 CDO75540.1 - 2e-06 27.4 0.8 0.15 11.7 0.0 3.3 3 0 0 3 3 3 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 CDO75540.1 - 7.6e-05 22.3 0.0 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 2OG-FeII_Oxy_5 PF13759.1 CDO75540.1 - 0.013 15.7 0.1 0.41 10.9 0.0 2.8 3 1 1 4 4 4 0 Putative 2OG-Fe(II) oxygenase GPI PF06560.6 CDO75540.1 - 0.02 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_4 PF08007.7 CDO75540.1 - 0.038 13.2 0.1 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein Pirin_C PF05726.8 CDO75540.1 - 0.093 12.8 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Pirin C-terminal cupin domain NAD_binding_10 PF13460.1 CDO75541.1 - 1.2e-12 48.1 0.1 1.9e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CDO75541.1 - 1.1e-06 28.2 0.1 1.7e-05 24.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 CDO75541.1 - 2.8e-05 23.2 0.4 3.7e-05 22.8 0.3 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 CDO75541.1 - 8.6e-05 21.8 0.6 0.00012 21.4 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CDO75541.1 - 0.00072 19.5 0.5 0.0014 18.6 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Fibrillarin PF01269.12 CDO75541.1 - 0.0021 17.0 0.1 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin 3Beta_HSD PF01073.14 CDO75541.1 - 0.0048 15.6 0.0 1.9 7.1 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CDO75541.1 - 0.026 13.4 0.1 0.14 11.0 0.0 2.1 1 1 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.10 CDO75541.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Transp_cyt_pur PF02133.10 CDO75542.1 - 2.9e-117 391.9 35.9 3.3e-117 391.7 24.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.20 CDO75543.1 - 5.9e-23 81.5 0.4 5.9e-23 81.5 0.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO75543.1 - 9.9e-19 68.0 0.0 1.3e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO75543.1 - 3.5e-06 26.8 0.1 6.7e-06 25.8 0.1 1.4 1 1 0 1 1 1 1 KR domain HHH_5 PF14520.1 CDO75543.1 - 0.0011 19.1 1.3 15 5.8 0.0 3.9 3 1 0 3 3 3 0 Helix-hairpin-helix domain NAD_binding_10 PF13460.1 CDO75543.1 - 0.005 16.8 0.7 0.047 13.7 0.5 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 CDO75543.1 - 0.014 15.0 0.2 0.2 11.2 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain B12-binding PF02310.14 CDO75543.1 - 0.019 14.8 0.3 0.069 13.0 0.1 1.9 1 1 1 2 2 2 0 B12 binding domain UPF0146 PF03686.8 CDO75543.1 - 0.02 14.7 0.1 0.05 13.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Epimerase PF01370.16 CDO75543.1 - 0.028 13.8 0.2 0.1 12.0 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Nol1_Nop2_Fmu_2 PF13636.1 CDO75543.1 - 0.058 13.4 0.0 0.15 12.1 0.0 1.6 2 0 0 2 2 1 0 pre-rRNA processing and ribosome biogenesis F420_oxidored PF03807.12 CDO75543.1 - 0.71 10.3 3.1 6.4 7.2 0.3 3.2 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent CENP-F_leu_zip PF10473.4 CDO75544.1 - 0.055 13.3 68.3 0.047 13.5 5.3 4.5 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1759 PF03564.10 CDO75544.1 - 0.78 9.5 18.5 0.021 14.6 4.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) DUF4112 PF13430.1 CDO75548.1 - 8.1e-31 106.0 0.1 1e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) YbhQ PF11076.3 CDO75548.1 - 0.12 12.0 0.2 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ Mid2 PF04478.7 CDO75553.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Alpha-amylase PF00128.19 CDO75554.1 - 1.9e-17 63.6 0.0 2.8e-13 49.9 0.0 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Sugar_tr PF00083.19 CDO75555.1 - 1.1e-75 254.9 19.6 1.3e-75 254.6 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO75555.1 - 1.8e-23 82.8 53.6 1.2e-21 76.8 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Exo_endo_phos PF03372.18 CDO75556.1 - 1.7e-15 57.6 0.1 2.1e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPF0081 PF03652.10 CDO75556.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) WD40 PF00400.27 CDO75557.1 - 1.3e-37 126.3 15.7 3.6e-10 39.3 0.0 8.6 9 0 0 9 9 9 7 WD domain, G-beta repeat RhoGEF PF00621.15 CDO75557.1 - 1.7e-32 112.7 1.1 2.4e-32 112.2 0.7 1.2 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 CDO75557.1 - 4.9e-20 72.0 0.0 1e-19 71.0 0.0 1.5 1 1 0 1 1 1 1 CNH domain PH_5 PF15405.1 CDO75557.1 - 2.1e-09 37.4 0.0 5.7e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PQQ_2 PF13360.1 CDO75557.1 - 9.2e-05 22.0 1.8 0.00047 19.7 1.2 2.2 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 CDO75557.1 - 0.00043 20.4 7.2 0.94 9.8 0.1 4.2 3 0 0 3 3 3 2 PQQ-like domain PH PF00169.24 CDO75557.1 - 0.0057 16.8 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 PH domain Glyoxal_oxid_N PF07250.6 CDO75557.1 - 0.26 10.3 0.0 0.48 9.4 0.0 1.3 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Lactonase PF10282.4 CDO75558.1 - 6.2e-11 41.9 0.0 1e-08 34.7 0.0 2.9 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller RdRP PF05183.7 CDO75560.1 - 2e-145 485.7 0.0 2.8e-145 485.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase rve PF00665.21 CDO75561.1 - 1.2e-07 31.8 0.1 2.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_1 PF01609.16 CDO75561.1 - 0.0063 16.0 0.1 0.0094 15.5 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain HTH_23 PF13384.1 CDO75561.1 - 0.0073 15.9 0.0 0.037 13.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain ELL PF10390.4 CDO75562.1 - 8.7e-06 25.1 0.0 1.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL Lipoxygenase PF00305.14 CDO75562.1 - 0.071 11.0 0.1 0.099 10.6 0.1 1.1 1 0 0 1 1 1 0 Lipoxygenase MAP7 PF05672.6 CDO75563.1 - 0.18 11.1 29.7 0.34 10.2 20.6 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF3987 PF13148.1 CDO75563.1 - 0.57 8.6 12.2 1 7.8 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Cupin_1 PF00190.17 CDO75564.1 - 1.4e-15 57.0 0.1 2.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 CDO75564.1 - 1.5e-05 24.4 0.0 2.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain SKG6 PF08693.5 CDO75564.1 - 0.065 12.5 2.4 0.13 11.5 1.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MIP-T3 PF10243.4 CDO75565.1 - 0.00016 20.2 0.4 0.00021 19.9 0.3 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Hid1 PF12722.2 CDO75565.1 - 0.023 12.4 0.0 0.026 12.2 0.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.7 CDO75565.1 - 0.061 11.2 6.3 0.083 10.8 4.4 1.1 1 0 0 1 1 1 0 Nop14-like family Gln-synt_C PF00120.19 CDO75566.1 - 1.3e-61 208.0 0.0 1.5e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CDO75566.1 - 6.4e-18 64.1 0.0 1e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain VID27 PF08553.5 CDO75567.1 - 2.2e-264 879.5 0.2 2.5e-264 879.3 0.1 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Nop14 PF04147.7 CDO75567.1 - 0.69 7.7 10.3 1.2 6.9 7.1 1.3 1 0 0 1 1 1 0 Nop14-like family Auto_anti-p27 PF06677.7 CDO75569.1 - 0.0091 15.7 0.2 0.11 12.3 0.1 2.1 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CDC27 PF09507.5 CDO75569.1 - 0.52 9.4 6.8 0.74 8.9 4.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAT1 PF09770.4 CDO75569.1 - 1.3 7.2 9.2 1.5 7.0 6.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNB PF00773.14 CDO75570.1 - 2.3e-93 313.0 0.1 4.4e-93 312.1 0.0 1.5 1 0 0 1 1 1 1 RNB domain Iso_dh PF00180.15 CDO75571.1 - 3.7e-101 338.5 0.0 4.2e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Snf7 PF03357.16 CDO75572.1 - 2e-23 82.6 23.8 3.9e-23 81.6 16.5 1.5 1 1 0 1 1 1 1 Snf7 DUF1571 PF07608.6 CDO75572.1 - 0.058 12.5 0.5 0.081 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) Ist1 PF03398.9 CDO75572.1 - 0.15 11.4 3.2 0.14 11.5 1.2 1.6 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF826 PF05696.6 CDO75572.1 - 0.27 11.3 3.9 1 9.5 2.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF826) Sec20 PF03908.8 CDO75572.1 - 0.32 10.7 3.4 0.47 10.1 1.1 2.3 1 1 0 1 1 1 0 Sec20 DUF1053 PF06327.9 CDO75572.1 - 6.8 7.1 6.3 2.4 8.5 2.3 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) GPI-anchored PF10342.4 CDO75573.1 - 8.6e-07 29.3 0.2 2.5e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Exo_endo_phos PF03372.18 CDO75574.1 - 1.5e-20 74.2 0.1 1.8e-20 73.9 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CDO75574.1 - 0.00056 19.5 0.0 0.0011 18.5 0.0 1.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Fungal_trans PF04082.13 CDO75575.1 - 1e-18 67.1 0.1 1.7e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Med17 PF10156.4 CDO75576.1 - 6.4e-29 100.5 0.0 7.9e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Ribosomal_L18p PF00861.17 CDO75577.1 - 6.8e-42 142.4 0.0 1.3e-41 141.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CDO75577.1 - 2.5e-35 120.9 2.2 2.5e-35 120.9 1.6 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region K_oxygenase PF13434.1 CDO75577.1 - 0.022 13.6 0.7 0.035 13.0 0.1 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF3340 PF11818.3 CDO75577.1 - 0.035 14.0 0.7 0.068 13.1 0.3 1.6 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) MtrA PF04208.9 CDO75577.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A RRM_1 PF00076.17 CDO75578.1 - 6.4e-15 54.5 0.0 9.4e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO75578.1 - 4.4e-10 39.3 0.0 6.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO75578.1 - 0.00089 19.0 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTNNBL PF08216.6 CDO75579.1 - 8.1e-26 89.7 1.7 1.7e-25 88.7 0.1 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 CDO75579.1 - 0.0025 17.5 0.2 0.11 12.3 0.0 3.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.3 CDO75579.1 - 0.012 15.3 0.7 1.4 8.5 0.0 3.3 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 CDO75579.1 - 0.012 15.8 4.2 2.9 8.2 0.0 4.0 4 1 0 4 4 4 0 HEAT repeats WD40 PF00400.27 CDO75580.1 - 7.7e-29 98.5 1.2 2.1e-06 27.4 0.0 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat UTP15_C PF09384.5 CDO75580.1 - 6.1e-09 35.7 0.9 1.4e-08 34.5 0.6 1.5 1 0 0 1 1 1 1 UTP15 C terminal Cytochrom_D1 PF02239.11 CDO75580.1 - 0.00021 19.7 0.1 0.037 12.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain CAF1C_H4-bd PF12265.3 CDO75580.1 - 0.077 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex TCTP PF00838.12 CDO75581.1 - 4.6e-67 225.1 2.6 5.2e-67 224.9 1.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Alpha_TIF PF02232.10 CDO75581.1 - 0.024 13.4 0.1 0.026 13.3 0.1 1.0 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) Thioredoxin PF00085.15 CDO75582.1 - 1.6e-58 194.8 0.5 6.4e-29 99.6 0.0 3.6 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CDO75582.1 - 5.3e-46 156.7 0.1 5.1e-35 120.9 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDO75582.1 - 9e-12 44.9 0.1 0.0012 18.8 0.0 4.0 3 1 0 3 3 3 3 Thioredoxin-like Thioredoxin_7 PF13899.1 CDO75582.1 - 9.6e-11 41.5 0.1 8.3e-05 22.5 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CDO75582.1 - 1.3e-10 41.4 1.3 0.0045 17.1 0.1 4.4 3 2 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 CDO75582.1 - 1.6e-07 31.0 0.2 0.017 14.6 0.0 3.4 3 0 0 3 3 3 3 Redoxin AhpC-TSA PF00578.16 CDO75582.1 - 1.1e-06 28.3 0.7 0.0047 16.5 0.0 3.3 3 1 0 3 3 3 2 AhpC/TSA family Thioredoxin_4 PF13462.1 CDO75582.1 - 0.00045 20.2 0.6 2 8.4 0.1 3.7 3 1 1 4 4 4 1 Thioredoxin Calsequestrin PF01216.12 CDO75582.1 - 0.0018 17.1 0.5 0.005 15.6 0.1 1.8 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_3 PF13192.1 CDO75582.1 - 0.052 13.3 0.0 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain DUF3325 PF11804.3 CDO75583.1 - 0.054 13.4 3.5 0.63 10.0 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) FAT PF02259.18 CDO75584.1 - 2.8e-71 240.3 5.6 8.2e-71 238.8 3.9 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CDO75584.1 - 2e-08 34.0 0.0 5.5e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_8 PF13181.1 CDO75584.1 - 0.0022 17.6 0.7 0.28 11.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat FATC PF02260.15 CDO75584.1 - 0.01 15.2 0.0 0.035 13.5 0.0 2.0 1 0 0 1 1 1 0 FATC domain TPR_2 PF07719.12 CDO75584.1 - 0.035 14.0 1.6 0.35 10.8 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CDO75584.1 - 0.2 11.3 7.9 0.14 11.8 1.0 3.3 3 0 0 3 3 3 0 TPR repeat DUF2722 PF10846.3 CDO75584.1 - 5.1 6.0 0.0 8.2 5.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Bromodomain PF00439.20 CDO75585.1 - 4.9e-24 84.0 0.2 8.9e-24 83.2 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Asp PF00026.18 CDO75586.1 - 1e-112 376.5 0.3 1.2e-112 376.2 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO75586.1 - 1.5e-10 41.2 0.0 3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CDO75586.1 - 1.1e-05 25.0 0.0 0.00026 20.5 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CDO75586.1 - 4.7e-05 23.7 0.1 0.042 14.3 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease WD40 PF00400.27 CDO75587.1 - 0.001 18.8 0.0 0.5 10.3 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Pkinase PF00069.20 CDO75588.1 - 7.3e-77 258.0 0.0 9.1e-77 257.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75588.1 - 1.2e-38 132.7 0.0 1.6e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO75588.1 - 7e-08 31.7 0.1 4.2e-07 29.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CDO75588.1 - 0.0061 15.6 0.2 0.017 14.1 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PCI PF01399.22 CDO75589.1 - 5e-12 46.0 0.0 2.5e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain Cohesin_load PF10345.4 CDO75589.1 - 0.0095 14.1 0.4 0.02 13.1 0.0 1.7 2 0 0 2 2 2 1 Cohesin loading factor Tropomyosin_1 PF12718.2 CDO75589.1 - 0.014 15.2 0.6 0.033 14.0 0.4 1.5 1 0 0 1 1 1 0 Tropomyosin like TPR_12 PF13424.1 CDO75589.1 - 0.035 14.0 0.3 0.12 12.3 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 CDO75589.1 - 0.041 14.5 5.5 4.1 8.3 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 CDO75589.1 - 0.051 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 SNF2_N PF00176.18 CDO75591.1 - 2.7e-13 49.3 0.0 2.7e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2439 PF10382.4 CDO75591.1 - 0.00012 22.1 0.6 0.27 11.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2439) DEAD PF00270.24 CDO75591.1 - 0.036 13.5 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO75592.1 - 3.6e-10 39.5 0.0 6.2e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CDO75592.1 - 1.8e-07 30.2 0.1 7.5e-07 28.2 0.0 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PUB PF09409.5 CDO75593.1 - 1.7e-08 34.1 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 PUB domain FAA_hydrolase_N PF09298.6 CDO75593.1 - 0.027 14.4 0.7 0.057 13.4 0.0 1.8 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal HTH_13 PF11972.3 CDO75593.1 - 0.068 13.0 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 HTH DNA binding domain PUB PF09409.5 CDO75594.1 - 1.1e-08 34.6 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 PUB domain DUF3336 PF11815.3 CDO75595.1 - 3.7e-40 136.7 2.0 6.3e-40 136.0 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CDO75595.1 - 2.7e-21 76.4 0.1 7.4e-21 75.0 0.1 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase Transposase_21 PF02992.9 CDO75597.1 - 0.0063 15.6 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF3759 PF12585.3 CDO75598.1 - 2.9e-38 129.6 5.7 3.5e-38 129.4 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Duffy_binding PF05424.6 CDO75598.1 - 0.03 14.1 0.2 0.035 13.9 0.2 1.1 1 0 0 1 1 1 0 Duffy binding domain BCDHK_Adom3 PF10436.4 CDO75599.1 - 1.5e-28 99.4 0.0 2.4e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CDO75599.1 - 4.5e-14 52.1 0.0 2.5e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CDO75599.1 - 0.00059 19.5 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CDO75599.1 - 0.06 13.1 0.0 0.19 11.5 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Pkinase PF00069.20 CDO75601.1 - 1.1e-63 214.7 0.2 2e-42 145.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75601.1 - 4.2e-28 98.1 0.2 4.9e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CDO75601.1 - 0.00015 20.9 0.0 0.0023 17.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CDO75601.1 - 0.00034 19.6 0.0 0.00085 18.3 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO75601.1 - 0.0023 17.7 2.8 0.1 12.3 1.9 2.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 CDO75601.1 - 0.011 16.2 0.1 0.027 14.9 0.1 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 CDO75601.1 - 0.02 13.7 0.1 0.034 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 CDO75601.1 - 0.021 14.1 0.0 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 CDO75601.1 - 0.051 12.4 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3818 PF12825.2 CDO75602.1 - 1.2e-109 366.1 0.4 5.8e-102 340.8 0.0 2.4 3 0 0 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CDO75602.1 - 8.4e-29 99.9 1.2 1.8e-28 98.8 0.8 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 CDO75602.1 - 3e-11 43.0 0.1 3.2e-10 39.8 0.1 2.5 1 1 0 1 1 1 1 PX domain TPR_7 PF13176.1 CDO75602.1 - 0.052 13.3 0.2 0.19 11.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3851 PF12962.2 CDO75602.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) DUF1682 PF07946.9 CDO75603.1 - 4.6e-37 127.5 0.0 5.5e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF677 PF05055.7 CDO75606.1 - 0.0023 16.6 0.4 0.0034 16.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) ApoLp-III PF07464.6 CDO75606.1 - 0.058 13.4 3.4 0.12 12.4 2.4 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.13 CDO75606.1 - 0.067 12.6 10.7 0.13 11.7 7.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Dak2 PF02734.12 CDO75606.1 - 0.13 11.8 8.5 0.68 9.5 1.5 2.5 2 1 1 3 3 3 0 DAK2 domain DUF883 PF05957.8 CDO75606.1 - 3.7 7.9 10.5 0.44 10.9 2.6 2.7 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Ribosomal_L29 PF00831.18 CDO75608.1 - 2.8e-09 36.4 0.6 2.8e-09 36.4 0.4 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein MitMem_reg PF13012.1 CDO75608.1 - 0.16 12.0 1.8 0.22 11.6 0.1 1.8 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Snapin_Pallidin PF14712.1 CDO75608.1 - 5.7 7.3 10.0 3.8 7.8 1.4 2.1 1 1 1 2 2 2 0 Snapin/Pallidin Pkinase PF00069.20 CDO75609.1 - 7.3e-58 195.7 0.0 2.8e-47 161.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75609.1 - 7.4e-37 126.8 0.0 2.8e-30 105.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CDO75609.1 - 1.2e-05 24.4 0.0 9.2e-05 21.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Flavi_glycop_C PF02832.11 CDO75609.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain Polysacc_deac_1 PF01522.16 CDO75610.1 - 4.8e-23 81.1 0.2 1.4e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF1180 PF06679.7 CDO75610.1 - 2.8 7.7 9.4 7.5 6.4 6.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TFIIF_alpha PF05793.7 CDO75611.1 - 5.1e-12 44.9 56.4 3e-10 39.1 4.0 4.2 2 2 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4407 PF14362.1 CDO75611.1 - 1.7 7.5 5.3 2.9 6.7 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HLH PF00010.21 CDO75612.1 - 9.5e-14 50.8 0.4 2e-13 49.7 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_L7Ae PF01248.21 CDO75613.1 - 3.8e-25 87.2 0.9 3.8e-25 87.2 0.6 2.3 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TRM PF02005.11 CDO75613.1 - 0.64 8.8 3.6 1.1 8.0 2.5 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DFP PF04127.10 CDO75614.1 - 0.082 12.5 4.0 0.077 12.6 1.5 1.9 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein DUF4411 PF14367.1 CDO75614.1 - 0.27 10.9 5.1 0.21 11.2 1.1 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4411) UPF0184 PF03670.8 CDO75614.1 - 5.2 7.3 9.9 69 3.7 3.9 3.8 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0184) THP2 PF09432.5 CDO75614.1 - 9.5 6.0 11.1 2.3 8.0 0.1 3.3 1 1 0 2 2 2 0 Tho complex subunit THP2 RFX_DNA_binding PF02257.10 CDO75615.1 - 6.7e-26 90.2 0.0 2.2e-25 88.5 0.0 1.9 2 0 0 2 2 2 1 RFX DNA-binding domain Glypican PF01153.14 CDO75615.1 - 0.21 10.1 0.4 0.32 9.5 0.3 1.2 1 0 0 1 1 1 0 Glypican Peptidase_M16_C PF05193.16 CDO75620.1 - 5.3e-16 58.8 0.0 6e-07 29.3 0.0 3.6 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CDO75620.1 - 6e-15 55.2 0.0 6.2e-14 52.0 0.0 2.3 1 1 1 2 2 2 1 Insulinase (Peptidase family M16) Amidase PF01425.16 CDO75622.1 - 4.2e-20 72.0 0.0 1.3e-12 47.3 0.0 2.1 1 1 1 2 2 2 2 Amidase F-box-like PF12937.2 CDO75623.1 - 0.012 15.3 0.1 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like CH PF00307.26 CDO75625.1 - 9.4e-75 247.6 0.0 1.1e-19 70.5 0.0 4.8 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CDO75625.1 - 1.7e-11 43.5 0.0 0.091 12.4 0.0 4.6 4 0 0 4 4 4 4 CAMSAP CH domain FKBP_C PF00254.23 CDO75626.1 - 1.8e-31 107.9 0.0 2.1e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GST_N_3 PF13417.1 CDO75627.1 - 6e-11 42.4 0.0 1.4e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO75627.1 - 1.5e-06 28.0 0.0 3.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO75627.1 - 0.013 15.3 0.5 0.029 14.2 0.2 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO75627.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bestrophin PF01062.16 CDO75628.1 - 5.5e-48 163.4 3.1 8.2e-26 90.6 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF4149 PF13664.1 CDO75628.1 - 0.076 13.0 0.2 0.076 13.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF572 PF04502.8 CDO75630.1 - 3.6 6.7 26.4 0.021 14.0 12.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) Dimer_Tnp_hAT PF05699.9 CDO75632.1 - 2.1e-16 59.3 0.0 4.5e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 CDO75632.1 - 0.0013 18.6 0.0 0.0045 16.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Ribosomal_L16 PF00252.13 CDO75635.1 - 2.9e-37 127.3 0.0 3.6e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e ThiG PF05690.9 CDO75636.1 - 0.043 12.8 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG MRP-S26 PF14943.1 CDO75636.1 - 0.045 13.2 2.1 0.089 12.3 1.5 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Atg14 PF10186.4 CDO75636.1 - 0.12 11.3 2.4 0.17 10.7 1.5 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HR1 PF02185.11 CDO75636.1 - 0.13 12.0 0.4 0.13 12.0 0.3 2.4 2 0 0 2 2 2 0 Hr1 repeat DUF972 PF06156.8 CDO75636.1 - 0.16 12.3 1.0 0.47 10.8 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF3864 PF12980.2 CDO75636.1 - 0.59 10.3 4.7 0.24 11.6 1.1 2.0 2 1 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) PRP3 PF08572.5 CDO75637.1 - 6.1e-57 192.5 2.1 1.3e-56 191.4 1.4 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CDO75637.1 - 5.2e-34 116.6 0.0 5.2e-34 116.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Ndc1_Nup PF09531.5 CDO75637.1 - 0.86 7.9 2.3 1.7 6.9 1.6 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DCP1 PF06058.8 CDO75638.1 - 2.3e-17 63.1 0.0 2e-15 56.9 0.0 2.2 2 0 0 2 2 2 2 Dcp1-like decapping family DDE_3 PF13358.1 CDO75639.1 - 2.4e-17 63.0 0.0 4.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CDO75639.1 - 3.4e-07 30.2 0.1 1.1e-06 28.6 0.0 1.9 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.1 CDO75639.1 - 0.041 13.5 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.1 CDO75640.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO75640.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Acetone_carb_G PF08882.6 CDO75641.1 - 0.008 16.1 0.5 0.022 14.7 0.1 1.8 2 0 0 2 2 2 1 Acetone carboxylase gamma subunit bZIP_1 PF00170.16 CDO75641.1 - 0.1 12.5 0.7 0.1 12.5 0.5 2.1 2 0 0 2 2 2 0 bZIP transcription factor Med12 PF09497.5 CDO75642.1 - 4.6e-25 87.3 0.0 1.1e-24 86.1 0.0 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 CDO75642.1 - 0.00063 18.3 0.0 0.0015 17.0 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain AIG1 PF04548.11 CDO75642.1 - 0.19 10.7 0.3 0.41 9.7 0.2 1.5 1 0 0 1 1 1 0 AIG1 family Ribosomal_S7 PF00177.16 CDO75644.1 - 1.8e-39 134.6 0.7 2.3e-39 134.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RRM_1 PF00076.17 CDO75645.1 - 3.1e-05 23.5 0.0 7.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO75645.1 - 0.049 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO75645.1 - 0.083 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2570 PF10828.3 CDO75645.1 - 0.76 9.3 2.6 1.5 8.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) ADIP PF11559.3 CDO75645.1 - 0.91 9.4 11.1 1.7 8.5 7.7 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.4 CDO75645.1 - 9.1 4.4 9.7 15 3.7 6.8 1.3 1 0 0 1 1 1 0 Transmembrane protein Borrelia_P83 PF05262.6 CDO75648.1 - 9.5 4.3 14.5 12 4.0 10.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Bax1-I PF01027.15 CDO75649.1 - 1.7e-43 148.6 26.9 2e-43 148.4 18.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 MFS_1 PF07690.11 CDO75650.1 - 9.3e-29 100.2 38.1 1.1e-28 100.0 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 CDO75650.1 - 0.0019 16.7 5.8 0.0019 16.7 4.0 2.7 3 0 0 3 3 3 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 CDO75650.1 - 0.087 12.6 0.0 0.087 12.6 0.0 4.4 4 1 1 5 5 5 0 MFS_1 like family DUF2109 PF09882.4 CDO75650.1 - 0.098 12.6 5.6 0.38 10.7 0.2 3.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) MDM31_MDM32 PF08118.6 CDO75651.1 - 3.9e-147 490.7 0.0 4.5e-147 490.5 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins CMAS PF02353.15 CDO75652.1 - 1.9e-08 33.7 0.1 4.3e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase F-box PF00646.28 CDO75652.1 - 0.001 18.6 0.2 0.0034 16.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 CDO75652.1 - 0.034 13.8 0.0 0.13 11.9 0.0 2.1 1 1 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 CDO75652.1 - 0.053 13.2 0.8 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 F-box-like DUF4648 PF15505.1 CDO75652.1 - 0.054 13.6 0.2 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4648) RasGAP PF00616.14 CDO75653.1 - 0.074 12.7 0.2 7.4 6.1 0.0 2.4 2 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase CSTF_C PF14304.1 CDO75653.1 - 0.24 10.7 2.0 0.23 10.7 0.1 1.9 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal IncA PF04156.9 CDO75653.1 - 1.5 8.3 10.1 11 5.5 3.6 2.7 2 0 0 2 2 2 0 IncA protein DUF605 PF04652.11 CDO75654.1 - 2 7.7 11.9 3.1 7.1 8.2 1.3 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 CDO75654.1 - 2.3 6.7 5.2 3 6.3 3.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein HMG_box_2 PF09011.5 CDO75655.1 - 0.00067 19.9 0.3 0.00067 19.9 0.2 2.9 3 0 0 3 3 3 1 HMG-box domain AAT PF03417.11 CDO75655.1 - 0.044 13.2 0.2 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF605 PF04652.11 CDO75655.1 - 6.2 6.1 19.9 11 5.2 13.8 1.4 1 0 0 1 1 1 0 Vta1 like adh_short PF00106.20 CDO75656.1 - 9.6e-10 38.6 0.0 1.9e-09 37.6 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CDO75656.1 - 1.7e-06 27.8 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 KR domain UIM PF02809.15 CDO75656.1 - 0.13 11.9 0.1 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif Pam16 PF03656.8 CDO75658.1 - 1.1e-18 67.2 1.6 1.1e-17 63.9 1.1 2.2 1 1 0 1 1 1 1 Pam16 DUF812 PF05667.6 CDO75659.1 - 0.013 14.0 16.9 0.02 13.4 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NIF PF03031.13 CDO75660.1 - 2.8e-16 59.5 0.1 4.7e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Nup_retrotrp_bd PF10599.4 CDO75660.1 - 0.54 10.9 7.3 1.4 9.6 5.1 1.7 1 0 0 1 1 1 0 Retro-transposon transporting motif KTI12 PF08433.5 CDO75661.1 - 1.9e-50 171.5 0.0 2.7e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Glyco_hydro_16 PF00722.16 CDO75663.1 - 4.5e-08 32.5 0.0 6.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Transposase_21 PF02992.9 CDO75664.1 - 1.9e-11 43.4 0.0 3.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 T2SM PF04612.7 CDO75664.1 - 0.004 16.9 0.1 0.011 15.5 0.1 1.8 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M DUF4218 PF13960.1 CDO75664.1 - 0.0065 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Asp PF00026.18 CDO75666.1 - 4.6e-71 239.6 0.7 6e-71 239.2 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO75666.1 - 9.3e-07 28.9 2.9 4.4e-06 26.7 1.3 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal PTPLA PF04387.9 CDO75667.1 - 3.6e-55 185.8 5.7 5.9e-55 185.1 4.0 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA bZIP_1 PF00170.16 CDO75667.1 - 4.3e-05 23.3 12.3 8.1e-05 22.5 6.6 2.1 1 1 1 2 2 2 1 bZIP transcription factor DUF2265 PF10023.4 CDO75667.1 - 0.09 11.8 2.7 0.33 10.0 1.1 2.0 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) DUF2933 PF11666.3 CDO75667.1 - 0.13 11.7 0.3 0.31 10.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) FlgN PF05130.7 CDO75667.1 - 2.2 8.4 9.6 3.7 7.7 6.7 1.3 1 0 0 1 1 1 0 FlgN protein Metal_resist PF13801.1 CDO75667.1 - 6.8 6.7 14.5 38 4.2 10.1 2.1 1 1 0 1 1 1 0 Heavy-metal resistance NIF PF03031.13 CDO75668.1 - 3.8e-52 176.1 0.1 5.1e-52 175.7 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RhoGAP PF00620.22 CDO75669.1 - 5.8e-39 133.1 0.1 2.1e-38 131.2 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain C1_1 PF00130.17 CDO75669.1 - 1.7e-07 30.8 20.2 2.1e-06 27.3 5.8 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.17 CDO75669.1 - 2.8e-05 24.1 4.9 2.8e-05 24.1 3.4 2.3 2 0 0 2 2 2 1 LIM domain Seryl_tRNA_N PF02403.17 CDO75669.1 - 0.18 11.7 15.9 0.33 10.9 2.6 2.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DZR PF12773.2 CDO75669.1 - 0.89 9.4 11.4 3.3 7.6 1.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon YlqD PF11068.3 CDO75669.1 - 1.2 9.1 17.1 0.024 14.6 0.8 3.1 2 1 1 3 3 3 0 YlqD protein NYD-SP28_assoc PF14775.1 CDO75669.1 - 5.3 6.8 7.7 11 5.8 1.5 2.8 2 1 1 3 3 3 0 Sperm tail C-terminal domain BTB PF00651.26 CDO75670.1 - 2.3e-13 50.1 0.0 3.8e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Glyco_hydro_18 PF00704.23 CDO75671.1 - 1.1e-06 28.3 2.5 1.9e-06 27.6 1.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SHIPPO-rpt PF07004.7 CDO75672.1 - 0.055 14.3 0.3 0.16 12.9 0.2 1.8 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat DUF3584 PF12128.3 CDO75672.1 - 0.11 9.8 80.8 0.23 8.7 34.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Rad21_Rec8_N PF04825.8 CDO75674.1 - 3.6e-43 146.0 0.3 6.1e-43 145.2 0.2 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CDO75674.1 - 3.5e-13 48.5 0.2 7.5e-13 47.4 0.2 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CDO75674.1 - 0.0041 16.7 1.5 0.066 12.7 0.0 2.6 3 0 0 3 3 3 1 ScpA/B protein PPR_2 PF13041.1 CDO75675.1 - 8.5e-44 147.3 2.3 6.1e-11 42.1 0.0 8.6 3 2 5 8 8 8 7 PPR repeat family PPR_3 PF13812.1 CDO75675.1 - 8.7e-27 91.1 20.0 0.00024 21.1 0.0 9.8 11 1 0 11 11 11 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 CDO75675.1 - 3e-17 61.7 1.9 0.00017 20.9 0.0 7.0 8 0 0 8 8 8 4 PPR repeat PPR PF01535.15 CDO75675.1 - 2.5e-14 52.1 15.7 0.00013 21.7 0.0 8.9 11 0 0 11 11 11 4 PPR repeat ECSIT PF06239.6 CDO75675.1 - 4.6e-05 22.3 0.4 0.4 9.4 0.1 4.4 4 1 0 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway Rep_fac_C PF08542.6 CDO75675.1 - 0.019 14.9 0.0 6.8 6.7 0.0 3.0 3 0 0 3 3 3 0 Replication factor C C-terminal domain ER-remodelling PF14755.1 CDO75677.1 - 0.035 14.1 1.3 0.053 13.5 0.3 1.7 2 0 0 2 2 2 0 Intracellular membrane remodeller Chitin_synth_1 PF01644.12 CDO75678.1 - 1.8e-80 268.5 0.1 2.6e-80 267.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 CDO75678.1 - 1.9e-25 89.2 5.3 5.1e-18 64.7 0.0 2.1 1 1 1 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 CDO75678.1 - 1.4e-24 85.5 1.0 4.4e-24 83.9 0.1 2.3 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 CDO75678.1 - 7.3e-07 29.0 5.6 7.3e-07 29.0 3.9 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CDO75678.1 - 7.4e-07 29.2 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Lactamase_B PF00753.22 CDO75679.1 - 5.2e-21 75.1 2.1 8e-21 74.5 1.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CDO75679.1 - 0.016 14.7 0.2 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain F-box-like PF12937.2 CDO75680.1 - 0.002 17.7 0.0 0.0045 16.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO75680.1 - 0.0065 16.0 0.3 0.12 12.0 0.2 2.5 1 1 0 1 1 1 1 F-box domain PRP8_domainIV PF12134.3 CDO75681.1 - 0.15 11.3 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 PRP8 domain IV core THRAP3_BCLAF1 PF15440.1 CDO75681.1 - 1.1 7.7 6.0 2 7.0 4.1 1.3 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Inhibitor_I9 PF05922.11 CDO75682.1 - 4.8e-05 23.8 0.1 7.3e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 HhH-GPD PF00730.20 CDO75683.1 - 1.3e-09 38.2 0.0 6.2e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DUF680 PF05079.7 CDO75683.1 - 1.4 9.4 4.0 14 6.2 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF680) TraV PF09676.5 CDO75683.1 - 2.5 8.8 6.1 0.48 11.1 0.3 2.3 2 1 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Pkinase PF00069.20 CDO75684.1 - 8.8e-53 179.0 0.0 3.1e-37 128.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO75684.1 - 4.1e-19 68.6 0.0 1.4e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO75684.1 - 7.4e-05 22.5 0.2 0.00016 21.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CDO75684.1 - 0.00023 20.2 0.0 0.0004 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CDO75684.1 - 0.00096 18.5 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CDO75684.1 - 0.042 12.9 0.1 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.3 CDO75684.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF387 PF04079.11 CDO75684.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) Oxidored_q6 PF01058.17 CDO75685.1 - 4.5e-22 78.0 0.0 6.3e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mnd1 PF03962.10 CDO75687.1 - 3.8e-49 166.9 0.2 4.2e-49 166.7 0.2 1.0 1 0 0 1 1 1 1 Mnd1 family IncA PF04156.9 CDO75687.1 - 0.00071 19.2 2.6 0.00099 18.7 1.8 1.1 1 0 0 1 1 1 1 IncA protein MAD PF05557.8 CDO75687.1 - 0.0028 15.8 2.3 0.0035 15.5 1.6 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Ribosomal_L29 PF00831.18 CDO75687.1 - 0.0092 15.6 1.3 0.06 13.0 0.0 2.2 1 1 1 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.1 CDO75687.1 - 0.062 13.6 3.5 0.11 12.7 2.4 1.4 1 0 0 1 1 1 0 Snapin/Pallidin IL28A PF15177.1 CDO75687.1 - 0.08 12.4 1.4 0.13 11.7 1.0 1.3 1 0 0 1 1 1 0 Interleukin-28A DUF4094 PF13334.1 CDO75687.1 - 0.094 13.1 0.3 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) TBPIP PF07106.8 CDO75687.1 - 0.15 11.5 1.9 0.32 10.5 1.3 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 CDO75687.1 - 0.18 10.6 1.3 0.22 10.4 0.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sec34 PF04136.10 CDO75690.1 - 3.2e-31 108.1 0.3 8.5e-31 106.7 0.2 1.8 1 0 0 1 1 1 1 Sec34-like family CCDC155 PF14662.1 CDO75690.1 - 0.0052 16.4 0.6 0.012 15.2 0.4 1.6 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 DUF1664 PF07889.7 CDO75690.1 - 0.0096 15.7 0.8 0.035 13.9 0.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Lectin_N PF03954.9 CDO75690.1 - 0.056 12.8 1.2 2 7.8 0.0 2.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Ricin_B_lectin PF00652.17 CDO75691.1 - 2.6e-07 30.7 0.0 3.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Sec2p PF06428.6 CDO75692.1 - 4e-08 33.0 13.2 4e-08 33.0 9.2 2.7 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Myosin_tail_1 PF01576.14 CDO75692.1 - 0.0017 16.1 13.1 0.0017 16.1 9.1 2.1 2 0 0 2 2 2 1 Myosin tail DUF4140 PF13600.1 CDO75692.1 - 0.0075 16.6 1.0 0.0075 16.6 0.7 4.1 3 1 1 4 4 4 1 N-terminal domain of unknown function (DUF4140) HSP70 PF00012.15 CDO75692.1 - 0.54 8.1 8.8 0.92 7.3 6.1 1.3 1 0 0 1 1 1 0 Hsp70 protein DUF972 PF06156.8 CDO75692.1 - 1.2 9.4 14.7 6.7 7.1 6.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) NAP PF00956.13 CDO75692.1 - 1.3 8.0 6.2 2.3 7.2 4.3 1.4 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) AAA_13 PF13166.1 CDO75692.1 - 2.4 6.5 10.5 0.36 9.2 4.0 1.7 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 CDO75692.1 - 3.9 4.6 19.5 0.2 8.9 6.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF2217 PF10265.4 CDO75692.1 - 4.3 5.9 7.5 0.58 8.8 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Fib_alpha PF08702.5 CDO75692.1 - 5.8 7.0 7.0 8.5 6.4 2.7 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PWWP PF00855.12 CDO75693.1 - 1e-18 67.3 0.2 1e-18 67.3 0.1 2.1 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 CDO75693.1 - 0.0034 16.8 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SPX PF03105.14 CDO75693.1 - 0.0085 15.9 11.8 0.0085 15.9 8.2 2.1 2 0 0 2 2 2 1 SPX domain TPR_9 PF13371.1 CDO75693.1 - 0.045 13.6 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DIOX_N PF14226.1 CDO75694.1 - 3.7e-27 95.1 0.0 6.5e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO75694.1 - 1e-16 61.0 0.0 1.7e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_C47 PF05543.8 CDO75695.1 - 0.095 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Staphopain peptidase C47 LCAT PF02450.10 CDO75696.1 - 7.4e-40 137.1 2.5 3.7e-24 85.4 0.2 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase EB1 PF03271.12 CDO75696.1 - 0.063 13.3 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 EB1-like C-terminal motif Trp_halogenase PF04820.9 CDO75697.1 - 1.1e-28 100.1 0.7 2.9e-13 49.2 0.0 3.9 2 2 0 3 3 3 2 Tryptophan halogenase FAD_binding_3 PF01494.14 CDO75697.1 - 5e-10 38.9 0.0 1.8e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CDO75697.1 - 5.4e-08 32.1 0.0 4.9e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDO75697.1 - 5.8e-07 29.4 0.3 3.9e-06 26.7 0.1 2.6 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDO75697.1 - 0.00018 21.4 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO75697.1 - 0.00044 18.8 0.1 0.00088 17.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 CDO75697.1 - 0.00053 19.1 0.0 0.0012 18.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 CDO75697.1 - 0.00075 18.4 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CDO75697.1 - 0.0057 15.5 0.0 0.01 14.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CDO75697.1 - 0.034 13.2 0.0 0.097 11.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 CDO75697.1 - 0.041 14.2 0.1 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CDO75697.1 - 0.062 12.2 0.0 0.14 11.0 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CDO75697.1 - 0.096 12.7 0.1 1.2 9.1 0.1 2.7 2 2 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO75697.1 - 0.12 12.1 0.1 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 CDO75697.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sensor PF13796.1 CDO75698.1 - 0.0016 18.0 0.7 0.0016 18.0 0.5 2.2 3 0 0 3 3 3 1 Putative sensor DUF458 PF04308.7 CDO75698.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF458) IGPS PF00218.16 CDO75699.1 - 9.4e-90 300.0 0.0 1.2e-89 299.6 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 CDO75699.1 - 1.2e-23 83.7 0.6 2e-23 82.9 0.4 1.4 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 CDO75699.1 - 2.4e-18 66.2 0.0 5.1e-17 61.9 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I QRPTase_C PF01729.14 CDO75699.1 - 0.00063 19.3 0.2 0.024 14.1 0.0 2.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain TMP-TENI PF02581.12 CDO75699.1 - 0.037 13.1 0.6 0.93 8.5 0.0 2.6 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI G-alpha PF00503.15 CDO75701.1 - 6.1e-130 433.3 0.0 7.6e-130 433.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CDO75701.1 - 1.4e-16 60.2 1.1 8.7e-12 44.6 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDO75701.1 - 8.5e-05 21.8 1.1 0.0066 15.6 0.0 2.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CDO75701.1 - 0.00023 21.6 0.6 0.16 12.4 0.0 2.9 3 1 0 3 3 3 2 Miro-like protein MMR_HSR1 PF01926.18 CDO75701.1 - 0.0029 17.5 0.0 0.44 10.5 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CDO75701.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CDO75701.1 - 0.025 14.0 0.1 6.6 6.1 0.0 2.8 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain zf-CHC2 PF01807.15 CDO75701.1 - 0.03 13.8 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger FtsK_SpoIIIE PF01580.13 CDO75701.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family BCS1_N PF08740.6 CDO75702.1 - 1.3e-23 83.5 0.6 3.1e-23 82.3 0.4 1.7 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CDO75702.1 - 1.8e-14 54.0 0.0 1.8e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CDO75702.1 - 0.00017 20.6 0.0 0.00034 19.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 CDO75702.1 - 0.00042 19.7 0.1 0.017 14.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CDO75702.1 - 0.0008 19.4 0.0 0.0008 19.4 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 CDO75702.1 - 0.0025 18.5 0.5 0.038 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CDO75702.1 - 0.0056 16.2 0.1 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 CDO75702.1 - 0.0097 15.7 0.2 0.035 13.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CDO75702.1 - 0.031 14.5 1.1 0.073 13.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 CDO75702.1 - 0.036 13.8 0.2 0.24 11.1 0.0 2.5 3 0 0 3 3 2 0 Part of AAA domain AAA_11 PF13086.1 CDO75702.1 - 0.042 13.4 2.7 5.5 6.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF4262 PF14081.1 CDO75702.1 - 0.081 13.0 0.2 0.28 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) AAA_23 PF13476.1 CDO75702.1 - 0.1 12.8 12.9 2.7 8.2 6.0 2.5 2 1 0 2 2 2 0 AAA domain DUF724 PF05266.9 CDO75702.1 - 0.26 10.8 9.5 0.5 9.9 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DDRGK PF09756.4 CDO75702.1 - 0.6 9.4 15.2 1.2e+02 2.0 12.6 2.6 3 1 0 3 3 3 0 DDRGK domain DUF1620 PF07774.8 CDO75706.1 - 7.4e-69 231.3 0.0 1.1e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CDO75706.1 - 5.6e-06 25.9 0.1 0.023 14.1 0.0 3.4 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.16 CDO75706.1 - 0.00062 19.1 0.2 0.0029 17.0 0.0 2.3 2 0 0 2 2 2 1 PQQ enzyme repeat UCR_hinge PF02320.11 CDO75707.1 - 1.3e-19 69.8 2.6 2.7e-19 68.8 1.8 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 CDO75707.1 - 0.019 14.5 3.2 0.02 14.4 2.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Brr6_like_C_C PF10104.4 CDO75707.1 - 0.13 11.7 0.3 0.16 11.4 0.1 1.3 1 1 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain DDRGK PF09756.4 CDO75707.1 - 0.18 11.1 4.9 0.22 10.8 3.4 1.0 1 0 0 1 1 1 0 DDRGK domain FAM176 PF14851.1 CDO75707.1 - 0.22 11.1 1.4 0.24 11.0 0.9 1.1 1 0 0 1 1 1 0 FAM176 family IncA PF04156.9 CDO75707.1 - 0.22 11.0 4.0 0.29 10.6 2.8 1.1 1 0 0 1 1 1 0 IncA protein MRVI1 PF05781.7 CDO75707.1 - 0.32 9.3 6.0 0.38 9.0 4.2 1.0 1 0 0 1 1 1 0 MRVI1 protein Daxx PF03344.10 CDO75707.1 - 0.4 9.1 6.9 0.4 9.1 4.8 1.1 1 0 0 1 1 1 0 Daxx Family ATG22 PF11700.3 CDO75707.1 - 0.67 8.3 1.9 0.82 8.0 1.2 1.2 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like DUF3306 PF11748.3 CDO75707.1 - 2.3 8.9 7.2 2.9 8.5 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DNA_pol_phi PF04931.8 CDO75707.1 - 8.1 4.0 8.0 8.1 4.0 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi His_Phos_2 PF00328.17 CDO75708.1 - 9.5e-13 48.1 0.0 2.2e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RNB PF00773.14 CDO75709.1 - 3.6e-93 312.4 0.0 4.9e-93 311.9 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 CDO75709.1 - 2.2e-05 24.5 0.2 9.1e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 PIN domain Ada3 PF10198.4 CDO75709.1 - 0.00031 20.5 0.2 0.00065 19.4 0.2 1.4 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DUF2890 PF11081.3 CDO75709.1 - 0.027 14.5 0.2 0.055 13.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) OB_RNB PF08206.6 CDO75709.1 - 0.035 13.5 2.0 0.12 11.9 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain p450 PF00067.17 CDO75710.1 - 4.9e-68 229.7 0.0 5.6e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PCI PF01399.22 CDO75711.1 - 9.9e-06 25.8 0.0 3.3e-05 24.1 0.0 1.9 1 1 1 2 2 2 1 PCI domain EF-hand_9 PF14658.1 CDO75711.1 - 0.11 12.3 0.0 24 4.9 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Kelch_1 PF01344.20 CDO75712.1 - 0.024 14.1 0.2 0.051 13.1 0.1 1.5 1 0 0 1 1 1 0 Kelch motif PMSR PF01625.16 CDO75713.1 - 8.7e-59 197.8 0.3 1.1e-58 197.5 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase GPI-anchored PF10342.4 CDO75714.1 - 2.7e-05 24.5 0.1 0.00011 22.6 0.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AA_permease_2 PF13520.1 CDO75715.1 - 4.2e-77 259.5 41.2 4.2e-77 259.5 28.6 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CDO75715.1 - 1.2e-13 50.1 27.5 1.2e-13 50.1 19.0 1.6 1 1 0 2 2 2 1 Amino acid permease Tyr-DNA_phospho PF06087.7 CDO75716.1 - 1.9e-42 145.4 0.0 8.2e-24 84.0 0.0 2.4 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 CDO75716.1 - 0.0002 21.0 0.0 0.022 14.5 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PMEI PF04043.10 CDO75717.1 - 0.0088 15.9 1.1 0.046 13.6 0.2 1.9 2 0 0 2 2 2 1 Plant invertase/pectin methylesterase inhibitor NAD_binding_4 PF07993.7 CDO75719.1 - 1e-33 116.3 0.0 1.6e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 CDO75719.1 - 2.3e-27 95.4 0.0 4.2e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 CDO75719.1 - 6e-11 42.2 0.0 1.7e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO75719.1 - 7e-05 22.9 0.0 0.00029 20.9 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CDO75719.1 - 0.00084 19.2 0.4 0.0038 17.1 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 CDO75719.1 - 0.002 18.3 0.0 0.0044 17.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 CDO75719.1 - 0.003 17.2 0.0 0.0093 15.6 0.0 1.9 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CDO75719.1 - 0.014 14.3 0.5 1.6 7.5 0.1 2.5 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 CDO75719.1 - 0.027 13.1 0.0 0.11 11.1 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 CDO75719.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 CDO75719.1 - 0.19 10.5 0.1 0.4 9.5 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 CDO75721.1 - 7.8e-21 74.1 16.7 3.6e-17 62.1 14.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Xpo1 PF08389.7 CDO75722.1 - 1.6e-09 37.8 0.4 1.3e-05 25.1 0.1 4.5 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.14 CDO75722.1 - 1.4e-06 28.1 0.0 0.00011 22.0 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3505 PF12013.3 CDO75724.1 - 0.0067 16.6 0.8 0.01 16.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Colicin_C PF12106.3 CDO75724.1 - 0.11 12.0 0.3 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Colicin C terminal ribonuclease domain Dimer_Tnp_hAT PF05699.9 CDO75725.1 - 0.00052 19.5 0.4 0.0011 18.5 0.3 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region OTT_1508_deam PF14441.1 CDO75726.1 - 1.9e-13 50.4 0.0 4.5e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase WD40 PF00400.27 CDO75727.1 - 8.2e-22 76.2 3.4 6.7e-09 35.3 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 CDO75727.1 - 1.8e-05 24.2 0.0 3.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) DivIC PF04977.10 CDO75727.1 - 0.069 12.6 2.4 0.13 11.7 1.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Docking PF08990.6 CDO75727.1 - 0.1 11.8 0.4 0.1 11.8 0.3 1.6 2 0 0 2 2 2 0 Erythronolide synthase docking CCDC144C PF14915.1 CDO75727.1 - 0.1 11.5 1.7 0.15 10.9 1.2 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Antimicrobial10 PF08105.6 CDO75727.1 - 0.31 10.6 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Metchnikowin family DJ-1_PfpI PF01965.19 CDO75728.1 - 2.8e-26 91.7 0.0 3.8e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CDO75728.1 - 4.8e-13 48.7 0.0 7.3e-13 48.1 0.0 1.3 1 1 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 CDO75728.1 - 0.0016 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain BPL_N PF09825.4 CDO75728.1 - 0.0085 14.9 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal NUC153 PF08159.7 CDO75729.1 - 4.1e-13 48.6 0.7 8.1e-13 47.7 0.5 1.5 1 0 0 1 1 1 1 NUC153 domain ATP-synt_C PF00137.16 CDO75730.1 - 0.015 15.1 1.3 0.061 13.2 0.9 2.1 1 1 0 1 1 1 0 ATP synthase subunit C SURF4 PF02077.10 CDO75731.1 - 4.8e-97 324.5 4.3 5.9e-97 324.2 3.0 1.0 1 0 0 1 1 1 1 SURF4 family HhH-GPD PF00730.20 CDO75732.1 - 1.2e-19 70.5 0.0 3e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 CDO75732.1 - 1.8e-07 30.5 0.2 1.1e-05 24.7 0.0 3.3 2 1 0 2 2 2 1 NUDIX domain HHH PF00633.18 CDO75732.1 - 0.011 15.4 0.5 0.027 14.1 0.1 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Gti1_Pac2 PF09729.4 CDO75733.1 - 2.2e-24 86.2 0.1 2.1e-21 76.5 0.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family DUF3395 PF11875.3 CDO75734.1 - 2.6e-30 105.0 0.4 5.4e-30 104.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 CDO75734.1 - 2.3e-20 72.1 0.4 4.6e-20 71.1 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L29 PF00831.18 CDO75734.1 - 0.082 12.6 0.4 0.082 12.6 0.3 2.2 3 0 0 3 3 3 0 Ribosomal L29 protein DUF155 PF02582.9 CDO75735.1 - 2.6e-28 99.1 0.0 3.3e-19 69.4 0.0 2.4 1 1 1 2 2 2 2 Uncharacterised ACR, YagE family COG1723 ADH_N PF08240.7 CDO75736.1 - 1.1e-32 112.0 2.1 1.9e-32 111.2 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO75736.1 - 2.7e-15 56.0 0.0 4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO75736.1 - 0.00059 20.7 0.0 0.0018 19.1 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 CDO75736.1 - 0.0012 17.9 0.3 0.0018 17.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 CDO75736.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2338 PF10100.4 CDO75736.1 - 0.029 12.7 0.0 0.041 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) NADH_4Fe-4S PF10589.4 CDO75736.1 - 0.057 12.5 2.0 0.17 11.0 1.4 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region AMP-binding PF00501.23 CDO75737.1 - 5.4e-78 262.2 0.0 7.1e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CDO75737.1 - 1.4e-08 35.5 1.3 6.5e-08 33.4 0.3 2.6 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain His_Phos_2 PF00328.17 CDO75738.1 - 4.3e-26 92.0 0.0 8.5e-25 87.8 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Cyt-b5 PF00173.23 CDO75739.1 - 2.6e-22 78.4 0.1 5e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CDO75739.1 - 2e-09 37.8 23.5 2.2e-08 34.5 14.0 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Sec5 PF15469.1 CDO75740.1 - 2.1e-57 193.7 0.7 7.1e-57 192.0 0.2 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec5 Chordopox_A13L PF05961.6 CDO75740.1 - 0.03 14.2 0.0 0.13 12.2 0.0 2.1 1 0 0 1 1 1 0 Chordopoxvirus A13L protein RVP PF00077.15 CDO75743.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease AMP-binding PF00501.23 CDO75744.1 - 4.8e-76 255.8 0.0 6.9e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CDO75744.1 - 2.1e-68 229.9 0.0 8.9e-68 227.8 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 CDO75744.1 - 1.1e-16 60.8 0.1 6.5e-16 58.3 0.0 2.4 3 0 0 3 3 3 1 Phosphopantetheine attachment site Epimerase PF01370.16 CDO75744.1 - 1.2e-09 37.9 0.0 2.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 CDO75744.1 - 2.4e-09 38.0 0.0 1e-08 35.9 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 CDO75744.1 - 2.7e-05 23.0 0.0 5.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 CDO75744.1 - 0.023 13.5 0.0 0.067 12.0 0.0 1.8 1 1 0 1 1 1 0 Condensation domain adh_short PF00106.20 CDO75744.1 - 0.084 12.7 0.2 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 short chain dehydrogenase P22_CoatProtein PF11651.3 CDO75744.1 - 0.17 10.4 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 IBR PF01485.16 CDO75745.1 - 7.7e-09 35.3 11.6 7.7e-09 35.3 8.1 1.9 2 0 0 2 2 2 1 IBR domain zf-C2H2_jaz PF12171.3 CDO75745.1 - 0.012 15.7 0.6 5.1 7.3 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CDO75745.1 - 0.66 10.4 8.2 3.3 8.2 0.1 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.1 CDO75745.1 - 6 6.2 9.6 27 4.1 5.5 2.6 2 1 0 2 2 2 0 zinc-ribbon domain DEAD PF00270.24 CDO75746.1 - 1.1e-35 122.6 0.0 3.3e-35 121.0 0.0 1.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO75746.1 - 4.8e-13 48.7 0.1 1.7e-12 47.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CDO75746.1 - 0.061 11.7 0.1 0.84 7.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Nbl1_Borealin_N PF10444.4 CDO75746.1 - 0.085 12.2 0.4 0.23 10.8 0.3 1.6 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal ResIII PF04851.10 CDO75746.1 - 0.087 12.6 0.0 0.25 11.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CDO75746.1 - 0.59 9.9 5.0 0.97 9.2 0.2 2.7 2 0 0 2 2 2 0 Part of AAA domain KH_1 PF00013.24 CDO75747.1 - 2.3e-10 39.9 0.0 2.4e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CDO75747.1 - 4.5e-06 26.1 0.9 0.00067 19.2 0.1 2.5 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.14 CDO75747.1 - 0.033 14.0 0.1 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein DUF3348 PF11828.3 CDO75747.1 - 0.049 13.0 0.2 0.093 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) 3Beta_HSD PF01073.14 CDO75748.1 - 1.4e-29 102.6 0.0 1.1e-28 99.7 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CDO75748.1 - 3.2e-13 49.6 0.0 7e-13 48.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CDO75748.1 - 8.1e-11 41.3 0.0 9.8e-10 37.7 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 CDO75748.1 - 7e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CDO75748.1 - 0.00033 19.6 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CDO75748.1 - 0.00037 20.5 0.0 0.0031 17.5 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CDO75748.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CDO75748.1 - 0.012 14.4 0.0 0.036 12.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CTP_synth_N PF06418.9 CDO75749.1 - 2.3e-103 345.0 0.7 4.1e-103 344.2 0.5 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CDO75749.1 - 1.2e-49 168.3 0.0 1.8e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.18 CDO75749.1 - 0.0011 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.8 CDO75749.1 - 0.002 17.5 0.0 0.0074 15.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 ADH_N PF08240.7 CDO75750.1 - 1.1e-29 102.4 0.5 2.4e-29 101.2 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO75750.1 - 1.9e-17 63.0 0.0 2.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 CDO75750.1 - 9.6e-05 21.5 0.3 0.00026 20.1 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 CDO75750.1 - 0.0059 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CDO75750.1 - 0.029 14.4 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.11 CDO75750.1 - 0.043 14.2 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CDO75750.1 - 0.043 12.7 0.0 0.056 12.4 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF2338 PF10100.4 CDO75750.1 - 0.064 11.6 0.0 0.093 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) Pyr_redox_2 PF07992.9 CDO75750.1 - 0.071 12.9 0.6 0.6 9.9 0.2 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDO75750.1 - 0.15 12.1 0.3 0.31 11.0 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.17 CDO75751.1 - 3e-49 167.7 0.0 9.1e-49 166.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 F-box PF00646.28 CDO75752.1 - 0.0016 18.0 1.5 0.0036 16.9 1.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO75752.1 - 0.0076 15.9 1.0 0.017 14.8 0.7 1.6 1 0 0 1 1 1 1 F-box-like Cellulase PF00150.13 CDO75753.1 - 5.7e-51 173.3 0.5 7.4e-51 173.0 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 CDO75753.1 - 2.4e-12 46.2 6.5 2.4e-12 46.2 4.5 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain JAB PF01398.16 CDO75755.1 - 5.2e-26 90.6 0.1 8.2e-26 89.9 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CDO75755.1 - 1.4e-06 27.7 0.0 2.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Oxidored-like PF09791.4 CDO75756.1 - 2.3e-14 52.5 0.5 2.3e-14 52.5 0.3 1.8 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Glyco_hydro_1 PF00232.13 CDO75757.1 - 9.2e-135 449.3 0.2 1.9e-134 448.3 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 ABC_tran PF00005.22 CDO75757.1 - 2.5e-07 31.0 2.2 8.7e-06 26.0 0.0 2.9 3 1 0 3 3 2 1 ABC transporter AAA_29 PF13555.1 CDO75757.1 - 2.4e-05 23.7 0.1 0.0023 17.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CDO75757.1 - 0.00021 21.3 1.7 0.0028 17.6 0.4 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CDO75757.1 - 0.00063 20.1 2.4 0.017 15.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CDO75757.1 - 0.00095 18.6 0.7 0.17 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CDO75757.1 - 0.0011 19.8 2.5 0.025 15.4 0.2 3.1 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 CDO75757.1 - 0.002 17.7 1.3 0.028 14.0 0.1 2.6 2 1 0 2 2 2 1 NACHT domain ArgK PF03308.11 CDO75757.1 - 0.0022 16.8 3.6 0.0028 16.4 0.1 2.4 2 0 0 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 CDO75757.1 - 0.0057 16.1 0.0 0.0057 16.1 0.0 2.5 2 1 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 CDO75757.1 - 0.0063 16.2 0.4 0.031 13.9 0.2 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SMC_N PF02463.14 CDO75757.1 - 0.0088 15.2 0.1 0.048 12.8 0.0 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Miro PF08477.8 CDO75757.1 - 0.01 16.3 0.8 0.03 14.8 0.2 2.1 2 0 0 2 2 1 0 Miro-like protein T2SE PF00437.15 CDO75757.1 - 0.019 13.8 0.1 0.11 11.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.1 CDO75757.1 - 0.03 14.3 0.5 0.03 14.3 0.3 2.9 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 CDO75757.1 - 0.033 14.1 0.3 1.2 9.1 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 CDO75757.1 - 0.034 14.4 0.8 1.2 9.3 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CDO75757.1 - 0.044 13.6 0.1 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CDO75757.1 - 0.053 13.2 2.6 0.46 10.2 0.2 3.5 3 1 0 3 3 3 0 Part of AAA domain AAA_33 PF13671.1 CDO75757.1 - 0.055 13.3 0.1 0.2 11.5 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CDO75757.1 - 0.075 13.1 0.1 0.65 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CDO75757.1 - 0.088 11.6 0.0 0.28 10.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 CDO75757.1 - 0.12 11.8 0.2 0.52 9.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 CDO75757.1 - 0.13 11.4 0.1 0.34 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CDO75757.1 - 0.14 12.0 0.0 0.14 12.0 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.12 CDO75757.1 - 0.18 11.5 0.8 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 CDO75757.1 - 0.24 10.7 1.7 0.58 9.5 0.1 2.3 3 0 0 3 3 3 0 AAA-like domain AAA_15 PF13175.1 CDO75757.1 - 0.31 10.0 0.1 0.73 8.8 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 CDO75757.1 - 0.47 10.2 2.3 1.2 8.9 0.2 2.5 2 0 0 2 2 2 0 Dynamin family Ribosomal_L18ae PF01775.12 CDO75758.1 - 9.4e-60 199.9 0.4 1.2e-59 199.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain IBR PF01485.16 CDO75759.1 - 1e-06 28.4 29.5 7.2e-06 25.7 9.3 2.9 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 CDO75759.1 - 6.1e-06 25.9 3.3 6.1e-06 25.9 2.3 3.5 3 1 1 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 CDO75759.1 - 0.0098 15.9 0.6 0.0098 15.9 0.4 3.2 2 1 0 2 2 2 1 RING-H2 zinc finger GPI-anchored PF10342.4 CDO75760.1 - 0.00035 20.9 0.5 0.00072 19.9 0.3 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pro_isomerase PF00160.16 CDO75762.1 - 6.2e-46 156.4 0.3 7e-46 156.2 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AA_permease_2 PF13520.1 CDO75763.1 - 2e-72 244.1 21.3 6.9e-72 242.3 14.7 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CDO75763.1 - 8.7e-15 54.0 17.0 4.2e-13 48.4 5.5 2.1 2 0 0 2 2 2 2 Amino acid permease HbrB PF08539.6 CDO75765.1 - 2.5e-35 121.6 0.0 3.6e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 HbrB-like OPT PF03169.10 CDO75766.1 - 6.4e-39 133.8 6.0 5.6e-38 130.7 4.2 1.9 1 1 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 CDO75767.1 - 1.4e-197 657.9 66.6 1.6e-197 657.7 46.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Nop25 PF09805.4 CDO75768.1 - 4.4e-19 68.9 27.4 4.4e-19 68.9 19.0 3.1 2 2 0 2 2 2 1 Nucleolar protein 12 (25kDa) Ish1 PF10281.4 CDO75768.1 - 0.31 11.1 0.2 0.31 11.1 0.1 2.8 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Methyltransf_16 PF10294.4 CDO75769.1 - 1.8e-12 47.0 0.0 2.6e-09 36.7 0.0 2.3 1 1 0 1 1 1 1 Putative methyltransferase V-SNARE_C PF12352.3 CDO75770.1 - 1.3e-17 63.6 0.3 3.8e-17 62.1 0.2 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CDO75770.1 - 3.4e-08 33.0 0.5 2.5e-07 30.3 0.0 2.3 2 1 1 3 3 3 1 Sec20 BAR_2 PF10455.4 CDO75770.1 - 0.013 14.4 0.1 0.014 14.2 0.1 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Wbp11 PF09429.5 CDO75770.1 - 0.015 15.2 1.2 2.1 8.3 0.3 2.4 2 0 0 2 2 2 0 WW domain binding protein 11 TelA PF05816.6 CDO75770.1 - 0.019 13.6 1.4 0.028 13.1 1.0 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Mito_fiss_reg PF05308.6 CDO75770.1 - 0.021 14.1 0.6 0.025 13.9 0.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3513 PF12026.3 CDO75770.1 - 0.025 14.1 0.4 0.038 13.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) DUF1673 PF07895.6 CDO75770.1 - 0.067 12.7 0.2 5.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) FUSC PF04632.7 CDO75770.1 - 0.14 10.6 2.0 0.26 9.6 1.4 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family Auxin_repressed PF05564.7 CDO75770.1 - 0.38 11.3 2.2 0.63 10.6 1.5 1.6 1 1 0 1 1 1 0 Dormancy/auxin associated protein COesterase PF00135.23 CDO75771.1 - 3.2e-92 309.9 0.0 5.8e-92 309.1 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CDO75771.1 - 0.004 16.3 0.1 0.0069 15.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CDO75771.1 - 0.0049 16.4 0.1 0.05 13.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Myb_DNA-bind_4 PF13837.1 CDO75773.1 - 2.6e-09 37.0 0.2 5e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO75773.1 - 2.4e-06 28.1 0.1 3.8e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO75773.1 - 4.6e-05 23.2 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO75773.1 - 0.0077 16.3 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sigma70_ner PF04546.8 CDO75773.1 - 0.13 11.8 4.9 0.14 11.7 2.4 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Myb_DNA-binding PF00249.26 CDO75773.1 - 0.17 11.9 1.4 0.38 10.8 0.5 2.1 2 1 0 2 2 2 0 Myb-like DNA-binding domain CENP-B_dimeris PF09026.5 CDO75773.1 - 5.6 7.2 9.1 12 6.2 6.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RVT_2 PF07727.9 CDO75774.1 - 9.2e-82 273.6 0.0 1.4e-81 273.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO75774.1 - 7.8e-20 71.1 0.4 1e-18 67.5 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain UBN2_2 PF14227.1 CDO75774.1 - 1e-11 44.4 0.0 2.1e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO75774.1 - 1.6e-11 43.6 0.0 4.6e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 CDO75774.1 - 6.4e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO75774.1 - 6.4e-05 22.6 1.7 0.00022 20.9 1.2 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CDO75774.1 - 0.049 13.1 3.0 0.15 11.5 2.1 1.8 1 0 0 1 1 1 0 Zinc knuckle HMG_box_2 PF09011.5 CDO75777.1 - 0.016 15.5 0.3 0.044 14.1 0.2 1.8 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.14 CDO75777.1 - 0.02 15.1 1.7 0.19 12.0 1.2 2.4 1 1 0 1 1 1 0 HMG (high mobility group) box Phasin PF05597.6 CDO75777.1 - 0.077 12.7 1.1 0.16 11.7 0.8 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Rad60-SLD PF11976.3 CDO75778.1 - 0.00012 21.6 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like AKAP95 PF04988.7 CDO75778.1 - 0.11 12.2 0.4 0.21 11.3 0.3 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) CDC45 PF02724.9 CDO75778.1 - 0.6 8.0 4.3 1.5 6.7 0.9 2.1 2 0 0 2 2 2 0 CDC45-like protein VID27 PF08553.5 CDO75778.1 - 2.5 6.1 3.1 3.7 5.6 2.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 CDO75778.1 - 3.4 5.4 8.2 0.94 7.3 1.2 2.0 2 0 0 2 2 2 0 Nop14-like family WD40 PF00400.27 CDO75780.1 - 1.3e-47 158.0 26.9 2.5e-10 39.8 0.0 10.5 10 0 0 10 10 10 8 WD domain, G-beta repeat NACHT PF05729.7 CDO75780.1 - 6.2e-05 22.7 0.0 0.00021 20.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 CDO75780.1 - 0.00022 19.6 0.1 0.022 13.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 CDO75780.1 - 0.00095 18.9 0.1 2.5 7.7 0.0 3.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A AAA_25 PF13481.1 CDO75780.1 - 0.026 13.9 0.3 0.086 12.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain Nucleoporin_N PF08801.6 CDO75780.1 - 0.046 12.4 2.4 0.27 9.9 0.0 2.6 1 1 0 3 3 3 0 Nup133 N terminal like AAA_22 PF13401.1 CDO75780.1 - 0.098 12.7 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain SAD_SRA PF02182.12 CDO75784.1 - 2.8e-22 78.6 0.2 1.3e-19 70.0 0.1 2.3 2 0 0 2 2 2 2 SAD/SRA domain UDG PF03167.14 CDO75787.1 - 2.6e-17 62.6 0.0 2e-16 59.7 0.0 2.4 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily bZIP_1 PF00170.16 CDO75788.1 - 1.5e-06 28.0 3.6 2.5e-06 27.3 2.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CDO75788.1 - 0.001 18.8 2.7 0.002 17.8 1.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper WD40_alt PF14077.1 CDO75788.1 - 0.029 13.9 0.4 0.063 12.9 0.3 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif HAP1_N PF04849.8 CDO75788.1 - 0.063 12.2 0.7 0.083 11.8 0.5 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region BMFP PF04380.8 CDO75788.1 - 0.28 11.3 3.9 0.45 10.6 2.7 1.3 1 0 0 1 1 1 0 Membrane fusogenic activity PMI_typeI PF01238.16 CDO75789.1 - 9.9e-59 199.1 0.0 7.7e-34 117.2 0.0 2.1 2 0 0 2 2 2 2 Phosphomannose isomerase type I Cupin_2 PF07883.6 CDO75789.1 - 0.0025 17.3 0.1 0.17 11.4 0.0 2.5 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 CDO75789.1 - 0.041 13.2 0.1 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) AraC_binding PF02311.14 CDO75789.1 - 0.13 11.9 0.0 0.54 9.9 0.0 2.0 3 0 0 3 3 3 0 AraC-like ligand binding domain Cupin_6 PF12852.2 CDO75789.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Cupin YcbB PF08664.5 CDO75789.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 YcbB domain Abhydrolase_1 PF00561.15 CDO75790.1 - 7.6e-30 104.1 0.0 6e-29 101.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDO75790.1 - 1.5e-26 93.7 0.0 2.1e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO75790.1 - 3.9e-13 49.3 0.0 1.6e-12 47.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CDO75790.1 - 0.00039 19.6 0.0 0.089 12.0 0.0 2.3 1 1 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 CDO75790.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase FA_hydroxylase PF04116.8 CDO75791.1 - 8.6e-11 42.2 26.2 8.6e-11 42.2 18.2 2.5 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily WD40 PF00400.27 CDO75792.1 - 3e-28 96.6 7.5 8.1e-07 28.6 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 CDO75792.1 - 0.0058 16.3 0.0 0.42 10.3 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Pup PF05639.6 CDO75793.1 - 0.49 10.9 4.6 15 6.2 0.7 2.4 1 1 1 2 2 2 0 Pup-like protein SIR2 PF02146.12 CDO75794.1 - 3.7e-30 104.9 0.0 6.2e-21 74.9 0.0 2.4 2 0 0 2 2 2 2 Sir2 family MIP-T3 PF10243.4 CDO75794.1 - 0.013 13.9 9.9 0.019 13.4 6.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BmKX PF09132.5 CDO75794.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 BmKX MSP1b PF03429.8 CDO75794.1 - 9.1 4.0 7.7 16 3.1 5.3 1.3 1 0 0 1 1 1 0 Major surface protein 1B p450 PF00067.17 CDO75795.1 - 1.7e-34 119.1 0.0 2.9e-34 118.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DSS1_SEM1 PF05160.8 CDO75796.1 - 1.3e-19 69.6 14.0 3.5e-19 68.3 9.7 1.7 1 1 0 1 1 1 1 DSS1/SEM1 family Sugar_tr PF00083.19 CDO75797.1 - 5.1e-33 114.3 26.6 3.9e-22 78.4 4.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CDO75797.1 - 1.6e-19 69.8 34.9 2.5e-18 65.9 24.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CDO75797.1 - 0.22 9.8 24.7 0.47 8.7 5.1 2.9 2 1 1 3 3 3 0 MFS/sugar transport protein TFIIF_beta PF02270.10 CDO75798.1 - 2.8e-38 132.3 0.0 1.6e-37 129.8 0.0 1.9 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 CDO75798.1 - 0.03 13.6 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit adh_short PF00106.20 CDO75799.1 - 0.025 14.4 0.3 0.043 13.7 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Abhydrolase_1 PF00561.15 CDO75800.1 - 6.2e-36 124.0 0.0 1.4e-35 122.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDO75800.1 - 1.3e-09 38.2 3.8 5.6e-09 36.2 2.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CDO75800.1 - 0.072 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Terpene_synth_C PF03936.11 CDO75801.1 - 5.9e-13 48.6 0.3 1.3e-12 47.5 0.2 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DUF4611 PF15387.1 CDO75802.1 - 0.42 10.7 2.9 9.1 6.5 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RVT_2 PF07727.9 CDO75804.1 - 8.1e-65 218.2 0.0 7.3e-60 201.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_21 PF02992.9 CDO75804.1 - 2.4e-08 33.3 0.0 4.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 gag_pre-integrs PF13976.1 CDO75804.1 - 4.8e-05 22.9 0.4 0.00013 21.5 0.3 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_4 PF14392.1 CDO75804.1 - 0.042 13.5 1.3 0.088 12.4 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Chromo PF00385.19 CDO75805.1 - 8.8e-08 31.7 0.1 1.5e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SelB-wing_2 PF09106.6 CDO75805.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix FlxA PF14282.1 CDO75806.1 - 1.3 8.9 7.5 3.9 7.4 0.1 2.3 2 0 0 2 2 2 0 FlxA-like protein SPX PF03105.14 CDO75806.1 - 3.7 7.2 12.3 5 6.8 1.5 2.1 2 0 0 2 2 2 0 SPX domain RP-C_C PF11800.3 CDO75806.1 - 5.6 6.6 13.1 9.1 5.9 3.5 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region DDE_3 PF13358.1 CDO75807.1 - 4.2e-05 23.3 0.0 4.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Sugar_tr PF00083.19 CDO75808.1 - 2.9e-126 421.6 22.3 3.3e-126 421.4 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO75808.1 - 1.7e-21 76.3 39.2 2.2e-17 62.8 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2763 PF10961.3 CDO75808.1 - 0.067 13.5 2.0 0.1 12.9 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) TFIIF_alpha PF05793.7 CDO75809.1 - 7.4 4.8 12.9 11 4.2 8.9 1.3 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Transposase_21 PF02992.9 CDO75810.1 - 1.5e-18 66.7 0.0 4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 Laminin_I PF06008.9 CDO75810.1 - 0.00071 18.9 3.7 0.00091 18.6 1.8 1.6 1 1 0 1 1 1 1 Laminin Domain I DUF4218 PF13960.1 CDO75810.1 - 0.0015 17.9 0.1 0.004 16.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) CENP-F_leu_zip PF10473.4 CDO75810.1 - 0.0051 16.6 10.5 1.5 8.6 7.3 2.3 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 CDO75810.1 - 0.044 13.6 2.1 0.12 12.2 0.1 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.1 CDO75810.1 - 0.046 13.0 1.8 0.092 12.0 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) ADIP PF11559.3 CDO75810.1 - 0.053 13.4 7.4 0.6 10.0 1.1 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 CDO75810.1 - 0.076 13.2 0.2 2.8 8.2 0.0 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.1 CDO75810.1 - 0.33 10.9 4.2 4.9 7.1 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.6 CDO75810.1 - 1.1 9.6 6.8 3.7 8.0 0.5 3.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal AAA_13 PF13166.1 CDO75810.1 - 1.5 7.1 3.0 2.4 6.5 2.0 1.2 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 CDO75810.1 - 3.6 7.1 7.8 0.94 9.1 0.7 2.4 1 1 1 2 2 2 0 Mnd1 family Phage_GPO PF05929.6 CDO75810.1 - 7.2 5.7 6.6 1.5 8.0 1.1 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase IncFII_repA PF02387.10 CDO75812.1 - 0.059 12.5 1.2 0.1 11.7 0.8 1.3 1 0 0 1 1 1 0 IncFII RepA protein family Cnd2 PF05786.9 CDO75813.1 - 1.1e-152 510.2 2.3 2.1e-151 505.9 1.6 2.0 1 1 0 1 1 1 1 Condensin complex subunit 2 Leo1 PF04004.8 CDO75816.1 - 5.1e-51 172.7 0.1 5.1e-51 172.7 0.0 2.2 2 0 0 2 2 2 1 Leo1-like protein Atx10homo_assoc PF09759.4 CDO75817.1 - 9.3e-26 89.5 0.0 1.8e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.1 CDO75817.1 - 0.00012 22.2 1.9 0.00025 21.2 0.1 2.2 2 0 0 2 2 2 1 HEAT repeats Arm_2 PF04826.8 CDO75817.1 - 0.056 12.5 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Armadillo-like NUDIX PF00293.23 CDO75819.1 - 3.5e-10 39.6 0.3 6.8e-09 35.4 0.2 2.7 1 1 0 1 1 1 1 NUDIX domain zf-UBP PF02148.14 CDO75820.1 - 4.2e-19 68.4 3.8 1.1e-18 67.0 2.6 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 CDO75820.1 - 3.9e-15 55.3 0.0 8e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.1 CDO75820.1 - 3.6e-09 36.3 9.5 3.6e-09 36.3 6.6 1.8 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 CDO75820.1 - 1.2e-05 25.3 2.5 2.8e-05 24.1 1.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDO75820.1 - 3.8e-05 23.2 6.6 8.1e-05 22.2 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO75820.1 - 8.3e-05 22.2 6.4 8.3e-05 22.2 4.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CDO75820.1 - 9.9e-05 21.9 6.7 9.9e-05 21.9 4.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO75820.1 - 0.00016 21.6 8.6 0.00016 21.6 5.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDO75820.1 - 0.00034 20.4 0.7 0.00065 19.4 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger ArfGap PF01412.13 CDO75820.1 - 0.014 15.1 0.4 0.014 15.1 0.3 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf zf-RING_UBOX PF13445.1 CDO75820.1 - 0.029 14.0 3.1 0.067 12.9 0.9 2.2 1 1 1 2 2 2 0 RING-type zinc-finger TerY-C PF15616.1 CDO75820.1 - 0.088 12.7 12.9 0.14 12.1 1.8 2.9 1 1 1 2 2 2 0 TerY-C metal binding domain zf-RING_4 PF14570.1 CDO75820.1 - 0.091 12.3 5.8 0.2 11.2 4.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_6 PF14259.1 CDO75820.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FlaC_arch PF05377.6 CDO75820.1 - 0.22 11.4 0.8 20 5.1 0.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RasGAP_C PF03836.10 CDO75820.1 - 0.24 11.1 6.0 0.36 10.5 0.7 2.3 1 1 1 2 2 2 0 RasGAP C-terminus DUF342 PF03961.8 CDO75820.1 - 0.26 9.6 6.7 0.46 8.8 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) zf-C3HC4_4 PF15227.1 CDO75820.1 - 0.65 9.9 5.2 2.6 7.9 3.7 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3138 PF11336.3 CDO75820.1 - 0.69 8.0 3.5 0.41 8.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) AAA_13 PF13166.1 CDO75820.1 - 1.7 7.0 10.9 2.6 6.3 7.6 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 CDO75820.1 - 1.7 6.4 12.6 2.3 5.9 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 CDO75820.1 - 2.9 6.7 15.4 5.7 5.8 9.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CorA PF01544.13 CDO75820.1 - 3 6.7 10.7 4.6 6.1 7.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DNA_pol_B PF00136.16 CDO75821.1 - 3.3e-144 481.1 0.2 5.2e-144 480.4 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CDO75821.1 - 4.2e-75 252.6 0.0 7.2e-75 251.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CDO75821.1 - 1.2e-23 82.8 6.4 1.2e-23 82.8 4.4 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 CDO75821.1 - 0.0025 17.3 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.8 CDO75821.1 - 0.0083 14.8 1.4 0.049 12.3 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.15 CDO75821.1 - 0.015 14.7 0.1 0.036 13.5 0.1 1.7 1 0 0 1 1 1 0 3'-5' exonuclease RNase_H_2 PF13482.1 CDO75821.1 - 0.017 14.9 0.3 0.071 12.9 0.2 2.1 1 1 0 1 1 1 0 RNase_H superfamily Ank_3 PF13606.1 CDO75822.1 - 0.0006 19.8 0.0 0.01 15.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CDO75822.1 - 0.00065 19.8 0.3 0.0026 17.9 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDO75822.1 - 0.00095 19.6 0.0 0.0021 18.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CDO75822.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 CDO75822.1 - 0.023 14.5 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeat Arg_repressor PF01316.16 CDO75822.1 - 0.041 13.4 0.2 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain IFT46_B_C PF12317.3 CDO75822.1 - 0.23 10.7 0.4 0.64 9.3 0.2 1.7 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal PMM PF03332.8 CDO75823.1 - 2.5e-107 357.4 0.1 2.9e-107 357.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Actin PF00022.14 CDO75825.1 - 4.8e-32 110.8 0.0 8.6e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CDO75825.1 - 0.007 15.0 0.0 0.012 14.2 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Ribosomal_L7Ae PF01248.21 CDO75826.1 - 6.7e-24 83.2 0.0 7.9e-24 82.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NIR_SIR PF01077.17 CDO75827.1 - 3e-45 153.3 0.0 6.6e-39 132.7 0.0 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 CDO75827.1 - 3.7e-34 116.1 0.1 4.2e-16 58.3 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 CDO75827.1 - 1.4e-31 109.4 0.0 2.5e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 CDO75827.1 - 0.01 15.3 0.4 0.043 13.3 0.1 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.2 CDO75827.1 - 0.036 14.0 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Aminotran_5 PF00266.14 CDO75828.1 - 1.5e-18 66.6 0.0 2e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V WD40 PF00400.27 CDO75829.1 - 6.5e-17 60.6 8.9 5.6e-06 26.0 0.2 6.0 5 1 0 5 5 5 5 WD domain, G-beta repeat tRNA_int_endo PF01974.12 CDO75830.1 - 1.3e-18 66.5 0.1 2.6e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 CDO75830.1 - 0.00015 21.2 0.0 0.018 14.6 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Nop25 PF09805.4 CDO75830.1 - 6.2 6.8 7.9 70 3.4 6.9 1.8 2 1 0 2 2 2 0 Nucleolar protein 12 (25kDa) SAC3_GANP PF03399.11 CDO75831.1 - 8e-56 188.8 2.5 2.7e-55 187.1 1.7 1.9 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CDO75831.1 - 2.7e-09 36.9 0.1 6.5e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Cytochrom_C1 PF02167.10 CDO75832.1 - 1e-84 283.5 0.0 1.2e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CDO75832.1 - 0.00037 20.5 0.0 0.00081 19.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CDO75832.1 - 0.013 16.3 0.3 0.03 15.1 0.1 1.8 2 1 0 2 2 2 0 Cytochrome c Tim17 PF02466.14 CDO75833.1 - 1.2e-25 89.9 4.8 1.4e-25 89.7 3.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HET PF06985.6 CDO75834.1 - 1.4e-21 77.1 6.3 8.4e-19 68.1 0.4 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 CDO75835.1 - 8e-128 426.8 21.0 9.2e-128 426.6 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO75835.1 - 9.3e-22 77.1 31.7 4e-18 65.2 5.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dak1 PF02733.12 CDO75836.1 - 1.7e-90 302.8 1.0 1.3e-46 158.7 0.3 2.1 1 1 1 2 2 2 2 Dak1 domain Dak2 PF02734.12 CDO75836.1 - 4e-18 65.6 0.5 5.2e-11 42.5 0.2 2.4 2 0 0 2 2 2 2 DAK2 domain UCH PF00443.24 CDO75837.1 - 5e-78 261.9 0.0 9.5e-78 261.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDO75837.1 - 3.3e-17 62.8 0.0 1.7e-10 40.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CDO75837.1 - 1.9e-15 57.0 0.4 5.4e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 DUSP domain DUF1712 PF08217.6 CDO75837.1 - 2.9e-15 55.5 0.0 4.3e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) USP7_C2 PF14533.1 CDO75837.1 - 0.0038 16.6 0.0 0.028 13.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal Zn-ribbon_8 PF09723.5 CDO75837.1 - 1.2 9.2 3.3 6 6.9 0.4 2.8 3 0 0 3 3 3 0 Zinc ribbon domain zf-CCCH PF00642.19 CDO75838.1 - 2.6e-07 30.1 16.7 0.038 13.6 1.0 5.4 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Herpes_capsid PF06112.6 CDO75838.1 - 4.6 7.2 11.9 1.7 8.6 6.1 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein MSP1_C PF07462.6 CDO75838.1 - 5.3 5.2 6.0 7.8 4.7 4.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Nucleoplasmin PF03066.10 CDO75838.1 - 7.3 6.0 15.0 12 5.4 10.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_L37ae PF01780.14 CDO75839.1 - 9e-41 137.6 10.5 1e-40 137.5 7.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 CDO75839.1 - 0.0019 17.9 2.2 0.0031 17.2 1.5 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 CDO75839.1 - 0.0037 16.9 4.3 0.063 13.0 0.1 2.3 1 1 1 2 2 2 2 BED zinc finger zf-FCS PF06467.9 CDO75839.1 - 0.017 14.7 2.3 0.24 11.0 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif OrfB_Zn_ribbon PF07282.6 CDO75839.1 - 0.022 14.4 1.4 0.031 13.9 1.0 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1364 PF07102.7 CDO75839.1 - 0.04 13.7 0.8 0.05 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Zn-ribbon_8 PF09723.5 CDO75839.1 - 0.12 12.3 1.8 0.59 10.1 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.10 CDO75839.1 - 0.12 11.9 5.9 0.97 9.0 0.1 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Elf1 PF05129.8 CDO75839.1 - 0.21 11.2 3.8 0.38 10.4 2.6 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like C1_1 PF00130.17 CDO75839.1 - 0.23 11.2 2.2 0.35 10.6 1.5 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_2 PF14445.1 CDO75839.1 - 0.4 10.6 3.9 0.76 9.7 2.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 A2L_zn_ribbon PF08792.5 CDO75839.1 - 0.68 9.4 0.1 0.68 9.4 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_4 PF07975.7 CDO75839.1 - 1.4 9.0 4.5 3.6 7.6 0.3 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain zf-H2C2_2 PF13465.1 CDO75839.1 - 5.4 7.4 7.1 1.9 8.9 0.7 2.2 1 1 1 2 2 2 0 Zinc-finger double domain DUF2706 PF10913.3 CDO75840.1 - 0.035 13.7 0.6 0.076 12.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) DUF4510 PF14971.1 CDO75841.1 - 0.067 13.3 0.4 0.08 13.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Med19 PF10278.4 CDO75841.1 - 0.1 12.2 6.1 0.12 12.0 4.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 BAF1_ABF1 PF04684.8 CDO75841.1 - 0.15 10.8 10.7 0.17 10.6 7.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 CDO75841.1 - 0.19 10.6 6.8 0.2 10.6 4.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Herpes_LMP1 PF05297.6 CDO75841.1 - 0.41 9.5 2.2 0.48 9.3 1.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SRP-alpha_N PF04086.8 CDO75841.1 - 0.49 9.7 5.2 0.57 9.5 3.6 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SelP_N PF04592.9 CDO75841.1 - 0.62 9.3 11.0 0.73 9.1 7.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Host_attach PF10116.4 CDO75841.1 - 0.77 9.9 10.8 0.98 9.6 7.5 1.1 1 0 0 1 1 1 0 Protein required for attachment to host cells FA_desaturase PF00487.19 CDO75841.1 - 0.8 9.0 6.1 0.92 8.8 4.2 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Macoilin PF09726.4 CDO75841.1 - 1.9 6.6 6.4 1.8 6.7 4.5 1.0 1 0 0 1 1 1 0 Transmembrane protein NicO PF03824.11 CDO75841.1 - 8 5.6 5.7 8.7 5.5 4.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Abhydrolase_3 PF07859.8 CDO75842.1 - 6.7e-37 127.1 0.0 1.2e-28 100.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CDO75842.1 - 4.1e-11 42.1 0.0 1.3e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CDO75842.1 - 0.0013 18.4 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family 4HBT PF03061.17 CDO75844.1 - 1.7e-10 40.8 0.0 3.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 CDO75844.1 - 2.8e-08 34.2 0.0 3.5e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 CDO75844.1 - 0.00011 21.2 0.1 0.0037 16.2 0.3 2.0 2 0 0 2 2 2 2 Acyl-ACP thioesterase AA_permease_2 PF13520.1 CDO75845.1 - 3.7e-82 276.1 47.5 4.9e-82 275.7 32.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CDO75845.1 - 1.3e-14 53.4 31.5 1.3e-14 53.4 21.8 1.7 2 0 0 2 2 2 1 Amino acid permease SUR7 PF06687.7 CDO75846.1 - 5.2e-13 49.0 11.8 5.2e-13 49.0 8.2 1.8 1 1 1 2 2 2 1 SUR7/PalI family LRR19-TM PF15176.1 CDO75846.1 - 0.091 12.4 1.3 0.28 10.8 0.9 1.8 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Claudin_2 PF13903.1 CDO75846.1 - 0.26 10.9 13.2 0.18 11.4 6.0 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RVT_1 PF00078.22 CDO75850.1 - 2.3e-20 72.8 0.0 4.9e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO75850.1 - 4e-14 53.0 0.0 7.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 CDO75850.1 - 4.7e-08 32.6 0.1 1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CDO75850.1 - 0.0053 17.0 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Peptidase_M14 PF00246.19 CDO75851.1 - 7.6e-54 183.1 0.0 1.2e-53 182.5 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Phytase-like PF13449.1 CDO75851.1 - 5.7e-25 88.2 0.0 1e-24 87.4 0.0 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase ATG13 PF10033.4 CDO75852.1 - 2.9e-29 102.1 0.0 3.9e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 13 Cupin_8 PF13621.1 CDO75853.1 - 1.6e-19 70.4 0.0 2.5e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 CDO75853.1 - 0.006 16.0 0.0 0.014 14.8 0.0 1.7 1 1 0 1 1 1 1 Cupin domain Cupin_4 PF08007.7 CDO75853.1 - 0.0094 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 CDO75853.1 - 0.054 13.7 0.0 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 JmjC domain, hydroxylase PTR2 PF00854.16 CDO75854.1 - 1.6e-45 155.5 11.6 3.3e-44 151.1 7.5 2.7 2 1 0 2 2 2 1 POT family MFS_1 PF07690.11 CDO75854.1 - 2.2e-08 33.2 27.8 5.6e-07 28.5 18.3 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1469 PF07332.6 CDO75854.1 - 0.0097 15.6 12.4 0.62 9.8 0.1 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF1469) DUF872 PF05915.7 CDO75854.1 - 1.2 8.9 5.8 14 5.5 1.3 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) GTP_EFTU PF00009.22 CDO75855.1 - 3.5e-61 205.9 0.1 5.6e-61 205.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CDO75855.1 - 7.3e-38 128.8 0.0 5.7e-37 125.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CDO75855.1 - 1.2e-21 76.3 0.0 2.7e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CDO75855.1 - 1e-13 50.9 0.0 2.6e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CDO75855.1 - 3.9e-13 49.3 0.1 2.5e-12 46.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CDO75855.1 - 4.1e-05 23.5 0.2 0.00012 22.0 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CDO75855.1 - 0.055 12.9 0.5 0.21 11.0 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2422 PF10337.4 CDO75856.1 - 1.5e-70 238.2 0.1 2.4e-70 237.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 CDO75856.1 - 4e-27 95.3 0.0 6.4e-25 88.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) Transaldolase PF00923.14 CDO75857.1 - 8e-97 323.8 0.0 9.3e-97 323.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase GST_N_3 PF13417.1 CDO75858.1 - 1.8e-09 37.7 0.1 3.6e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO75858.1 - 6.7e-06 26.0 0.1 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain LRR_6 PF13516.1 CDO75859.1 - 1.6e-13 49.2 22.3 0.0082 16.1 0.0 9.0 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.2 CDO75859.1 - 3.2e-11 42.5 15.5 0.0011 18.5 1.0 6.5 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDO75859.1 - 4.1e-07 29.1 8.4 52 4.4 0.0 9.2 11 0 0 11 11 11 0 Leucine Rich Repeat LRR_8 PF13855.1 CDO75859.1 - 0.00031 20.4 17.7 0.0032 17.1 1.2 5.4 4 2 0 4 4 4 2 Leucine rich repeat GAT PF03127.9 CDO75859.1 - 0.0061 16.5 0.2 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 GAT domain LRR_7 PF13504.1 CDO75859.1 - 0.17 12.1 22.2 84 4.0 0.1 9.1 10 0 0 10 10 10 0 Leucine rich repeat DUF4551 PF15087.1 CDO75859.1 - 6.1 5.0 7.3 2.3 6.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4551) AhpC-TSA PF00578.16 CDO75860.1 - 3.4e-27 94.5 0.0 4.8e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CDO75860.1 - 1.1e-16 60.7 0.0 1.6e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CDO75860.1 - 0.003 17.4 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme HMG14_17 PF01101.13 CDO75860.1 - 0.0047 17.5 7.3 0.013 16.2 5.0 1.8 1 0 0 1 1 1 1 HMG14 and HMG17 WH1 PF00568.18 CDO75861.1 - 6.3e-26 90.2 0.0 9.3e-26 89.7 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 CDO75861.1 - 3.5e-07 30.5 0.2 9.5e-07 29.1 0.1 1.9 1 1 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 CDO75861.1 - 0.011 15.3 0.1 0.011 15.3 0.1 2.2 2 0 0 2 2 2 0 WH2 motif DUF2076 PF09849.4 CDO75861.1 - 0.27 11.2 4.7 0.083 12.9 0.8 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) EF-hand_1 PF00036.27 CDO75862.1 - 5e-43 141.1 11.4 2.4e-10 38.9 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDO75862.1 - 2.2e-38 130.1 3.4 4.5e-21 74.7 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CDO75862.1 - 7.6e-35 118.3 10.5 4.4e-17 61.4 0.3 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CDO75862.1 - 1.1e-31 105.8 6.3 1.9e-09 36.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CDO75862.1 - 4.8e-29 98.3 6.4 7.7e-07 28.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CDO75862.1 - 1.2e-14 53.9 0.1 1.9e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CDO75862.1 - 7.7e-10 38.4 1.3 2e-05 24.2 0.1 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CDO75862.1 - 2.1e-09 37.3 0.0 0.00016 21.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CDO75862.1 - 5e-08 32.4 0.4 0.014 15.0 0.0 3.4 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CDO75862.1 - 2.9e-06 27.1 0.6 1.4e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 CDO75862.1 - 0.00028 20.3 1.5 0.00033 20.1 1.0 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EF-hand_like PF09279.6 CDO75862.1 - 0.0011 18.9 0.3 0.013 15.5 0.1 2.3 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 CDO75862.1 - 0.0015 18.2 0.2 0.24 11.1 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.8 CDO75862.1 - 0.0031 17.0 0.1 0.23 10.9 0.0 2.4 1 1 0 2 2 2 1 Caleosin related protein Poly_export PF02563.11 CDO75862.1 - 0.016 14.9 0.2 4.1 7.2 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein RNA_pol_Rpb4 PF03874.11 CDO75862.1 - 0.036 14.0 1.2 6 6.9 0.1 2.4 3 0 0 3 3 2 0 RNA polymerase Rpb4 Tenui_NCP PF04876.7 CDO75862.1 - 0.048 13.2 0.1 0.75 9.3 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein MotA_activ PF09114.5 CDO75862.1 - 0.052 13.3 0.1 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain LNS2 PF08235.8 CDO75862.1 - 0.099 12.2 0.1 0.42 10.1 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Toprim_2 PF13155.1 CDO75862.1 - 0.15 12.4 1.1 12 6.2 0.2 2.6 1 1 1 2 2 2 0 Toprim-like VCBS PF13517.1 CDO75862.1 - 7.5 7.0 7.0 17 5.8 0.4 2.6 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Proteasome PF00227.21 CDO75863.1 - 9.5e-36 122.8 0.0 1.2e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Rad60-SLD PF11976.3 CDO75864.1 - 0.00011 21.8 0.0 0.00029 20.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like AKAP95 PF04988.7 CDO75864.1 - 0.095 12.4 0.6 0.19 11.5 0.4 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) CDC45 PF02724.9 CDO75864.1 - 0.34 8.9 3.6 1 7.2 0.6 2.1 2 0 0 2 2 2 0 CDC45-like protein VID27 PF08553.5 CDO75864.1 - 2.5 6.2 3.1 3.6 5.6 2.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 CDO75864.1 - 4.1 5.2 8.6 1.1 7.0 1.4 2.0 2 0 0 2 2 2 0 Nop14-like family Myb_DNA-bind_4 PF13837.1 CDO75865.1 - 1.6e-09 37.7 0.1 4.1e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO75865.1 - 5e-07 30.2 0.1 9.5e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO75865.1 - 3.5e-05 23.5 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO75865.1 - 0.0056 16.7 0.1 0.017 15.2 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myc_N PF01056.13 CDO75865.1 - 0.019 14.1 3.8 0.022 13.9 1.8 1.6 1 1 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 CDO75865.1 - 0.022 14.9 1.6 0.049 13.8 1.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myb_DNA-binding PF00249.26 CDO75865.1 - 0.15 12.1 1.7 0.36 10.9 0.6 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain PBP1_TM PF14812.1 CDO75865.1 - 0.66 10.3 4.8 0.58 10.5 1.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_Tnp_4 PF13359.1 CDO75866.1 - 1.3e-28 99.5 0.0 1.9e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 CDO75866.1 - 2e-06 27.4 0.0 1.7e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 CDO75866.1 - 1.3e-05 24.7 0.0 0.00011 21.6 0.0 2.0 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO75866.1 - 0.00015 21.9 0.1 0.0003 20.9 0.1 1.5 1 0 0 1 1 1 1 Transposase DDE domain UVR PF02151.14 CDO75866.1 - 0.32 10.5 2.3 0.63 9.6 1.6 1.4 1 0 0 1 1 1 0 UvrB/uvrC motif Myb_DNA-bind_4 PF13837.1 CDO75867.1 - 2.2e-09 37.2 0.1 4.2e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO75867.1 - 9.3e-07 29.3 0.1 1.5e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO75867.1 - 6.1e-05 22.8 0.1 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO75867.1 - 0.016 15.3 0.1 0.039 14.0 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CDO75867.1 - 0.11 12.5 1.6 0.24 11.5 0.6 2.0 2 1 0 2 2 2 0 Myb-like DNA-binding domain Sigma70_ner PF04546.8 CDO75867.1 - 0.13 11.8 3.7 0.093 12.3 1.3 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 CDO75867.1 - 1.6 9.0 6.7 3.5 7.9 4.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Retrotrans_gag PF03732.12 CDO75868.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.5 2 0 0 2 2 2 0 Retrotransposon gag protein RTA1 PF04479.8 CDO75869.1 - 4.1e-46 157.3 2.9 5.1e-46 156.9 2.0 1.1 1 0 0 1 1 1 1 RTA1 like protein SLAC1 PF03595.12 CDO75869.1 - 0.013 14.1 6.7 0.022 13.4 4.6 1.4 1 1 0 1 1 1 0 Voltage-dependent anion channel DUF4131 PF13567.1 CDO75869.1 - 4.5 6.6 9.5 1.6 8.0 0.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2975 PF11188.3 CDO75869.1 - 7.7 6.2 12.0 0.79 9.4 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2975) NUDIX PF00293.23 CDO75870.1 - 3.8e-09 36.2 0.0 8.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain PIF1 PF05970.9 CDO75871.1 - 6.1e-35 120.8 0.0 3.5e-15 55.8 0.1 3.1 2 1 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 CDO75871.1 - 6.6e-05 22.5 0.0 0.0022 17.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.9 CDO75871.1 - 9.5e-05 20.3 0.1 0.00029 18.7 0.0 1.7 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 CDO75871.1 - 0.00033 20.7 0.0 0.00079 19.5 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 CDO75871.1 - 0.0018 18.2 0.2 0.005 16.8 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 CDO75871.1 - 0.0021 17.3 0.0 0.0048 16.1 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.1 CDO75871.1 - 0.012 15.2 0.1 0.13 12.0 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain Viral_helicase1 PF01443.13 CDO75871.1 - 0.027 14.0 0.8 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CDO75871.1 - 0.046 12.6 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 CDO75871.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CDO75871.1 - 0.076 13.3 0.1 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 CDO75871.1 - 0.11 12.5 0.2 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.17 CDO75872.1 - 3.2e-58 197.4 0.0 7.8e-58 196.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 UVR PF02151.14 CDO75872.1 - 0.14 11.7 0.7 0.7 9.4 0.0 2.3 2 0 0 2 2 2 0 UvrB/uvrC motif APH PF01636.18 CDO75873.1 - 0.0064 16.2 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 CDO75873.1 - 0.034 12.7 0.0 0.04 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF4131 PF13567.1 CDO75874.1 - 5.1 6.4 9.5 7.2 5.9 6.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1700 PF08006.6 CDO75874.1 - 5.1 6.3 14.0 0.29 10.3 5.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Prp19 PF08606.6 CDO75875.1 - 1.8e-31 107.6 3.2 1.8e-31 107.6 2.2 1.8 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 CDO75875.1 - 6.1e-17 60.7 0.0 3e-05 23.7 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat U-box PF04564.10 CDO75875.1 - 2e-06 27.6 0.0 7.8e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.3 CDO75875.1 - 8.9e-06 25.1 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3312 PF11768.3 CDO75875.1 - 0.00025 19.4 0.0 0.00043 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Rtf2 PF04641.7 CDO75875.1 - 0.014 14.6 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4073 PF13285.1 CDO75875.1 - 0.09 12.1 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) HNOB PF07700.10 CDO75875.1 - 0.12 11.8 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 Heme NO binding Cep57_CLD_2 PF14197.1 CDO75875.1 - 8.7 6.3 6.9 3.6 7.6 0.5 2.9 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 TPR_1 PF00515.23 CDO75876.1 - 6.4e-26 88.8 1.6 9e-10 37.7 0.1 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 CDO75876.1 - 9.3e-26 89.2 10.0 2.7e-17 62.1 3.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CDO75876.1 - 2.1e-21 74.0 4.6 1.1e-08 34.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CDO75876.1 - 7.8e-15 53.7 2.0 9.3e-05 22.3 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO75876.1 - 1.3e-13 50.2 0.7 9.2e-06 25.8 0.0 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CDO75876.1 - 2.6e-13 48.6 1.1 4e-06 26.2 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDO75876.1 - 4.3e-12 46.3 12.0 1.9e-05 25.1 0.2 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 CDO75876.1 - 2.2e-11 42.6 0.3 2.4e-05 23.7 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO75876.1 - 2e-08 34.4 0.6 0.0012 19.1 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDO75876.1 - 3.6e-08 33.2 5.2 2.1e-06 27.5 0.5 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CDO75876.1 - 5.6e-07 29.6 2.5 0.00015 21.7 0.0 2.4 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CDO75876.1 - 5.1e-05 23.0 0.2 0.09 12.6 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 CDO75876.1 - 0.00085 19.6 0.5 0.27 11.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDO75876.1 - 0.0077 16.0 0.1 0.1 12.4 0.0 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 CDO75876.1 - 0.063 13.5 0.7 1.6 9.0 0.1 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain Nol1_Nop2_Fmu PF01189.12 CDO75876.1 - 0.16 11.3 0.1 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 NOL1/NOP2/sun family TPR_20 PF14561.1 CDO75876.1 - 0.79 9.8 3.3 4.8 7.3 0.0 2.9 2 1 2 4 4 3 0 Tetratricopeptide repeat Spc7 PF08317.6 CDO75877.1 - 1.1e-36 126.2 2.3 9.9e-29 100.0 0.0 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein Spc7_C2 PF15577.1 CDO75877.1 - 0.0041 16.7 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 PspA_IM30 PF04012.7 CDO75877.1 - 0.0061 15.9 5.1 0.014 14.7 3.5 1.5 1 0 0 1 1 1 1 PspA/IM30 family TBPIP PF07106.8 CDO75877.1 - 0.054 13.0 1.3 0.13 11.8 0.9 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PadR PF03551.9 CDO75877.1 - 0.11 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family IncA PF04156.9 CDO75877.1 - 5.1 6.6 11.0 8.8 5.8 5.3 2.4 2 0 0 2 2 2 0 IncA protein Kinesin PF00225.18 CDO75878.1 - 3.7e-82 275.7 0.0 4.5e-81 272.1 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain Nop14 PF04147.7 CDO75878.1 - 8.6 4.1 35.8 31 2.2 24.8 1.8 1 1 0 1 1 1 0 Nop14-like family Peptidase_M32 PF02074.10 CDO75879.1 - 1.1 7.8 5.4 1.8 7.0 3.8 1.3 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DIE2_ALG10 PF04922.7 CDO75880.1 - 6.5e-74 249.2 23.1 6.3e-37 127.4 10.0 2.9 2 1 0 2 2 2 2 DIE2/ALG10 family TauD PF02668.11 CDO75881.1 - 4.8e-52 177.1 0.2 5.9e-52 176.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cu-oxidase_3 PF07732.10 CDO75881.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Multicopper oxidase OPT PF03169.10 CDO75882.1 - 2.8e-181 604.1 52.8 3.5e-181 603.8 36.6 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein C2 PF00168.25 CDO75883.1 - 1.1e-70 233.5 9.4 2e-14 53.1 0.1 5.5 5 0 0 5 5 5 5 C2 domain PID_2 PF14719.1 CDO75883.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) DDE_3 PF13358.1 CDO75884.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO75884.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain GST_N_3 PF13417.1 CDO75885.1 - 1.3e-13 50.9 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO75885.1 - 3.5e-08 33.3 0.0 1.3e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO75885.1 - 0.00018 21.5 0.0 0.00065 19.8 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO75885.1 - 0.011 15.6 0.3 0.026 14.3 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ATP_bind_1 PF03029.12 CDO75886.1 - 1.2e-71 240.9 0.0 1.5e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 CDO75886.1 - 0.069 13.0 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDO75886.1 - 0.13 13.0 7.4 0.056 14.2 1.8 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CDO75886.1 - 0.19 11.6 0.7 1.9 8.4 0.5 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase NMO PF03060.10 CDO75887.1 - 1.1e-38 133.1 0.6 1.8e-35 122.6 0.2 2.0 1 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 CDO75887.1 - 0.00038 19.4 0.1 0.00059 18.7 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 CDO75888.1 - 3.5e-50 171.0 0.1 1.5e-49 168.9 0.1 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 CDO75888.1 - 1.4e-06 27.4 0.6 3.3e-06 26.1 0.4 1.6 1 1 1 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CDO75888.1 - 0.0063 15.8 0.3 0.019 14.2 0.2 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein Trp_syntA PF00290.15 CDO75888.1 - 0.0094 14.5 0.0 0.022 13.2 0.0 1.6 1 0 0 1 1 1 1 Tryptophan synthase alpha chain IMPDH PF00478.20 CDO75888.1 - 0.02 13.8 5.2 0.085 11.7 0.1 2.9 3 1 0 4 4 4 0 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 CDO75888.1 - 0.041 12.8 0.1 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase LSM PF01423.17 CDO75889.1 - 1.3e-14 53.4 0.0 1.9e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain RhoGEF PF00621.15 CDO75893.1 - 0.04 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 RhoGEF domain LRR_4 PF12799.2 CDO75894.1 - 1e-08 34.5 0.2 0.01 15.4 0.0 3.6 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDO75894.1 - 5.8e-06 25.6 0.2 0.5 10.5 0.0 4.5 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 CDO75894.1 - 6.2e-06 25.7 0.3 1.1 9.5 0.0 5.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.1 CDO75894.1 - 0.0021 17.7 2.0 2.7 7.8 0.1 3.3 2 1 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 CDO75894.1 - 0.0052 16.7 3.7 3 8.4 0.0 4.3 4 0 0 4 4 4 2 Leucine rich repeat Aminotran_1_2 PF00155.16 CDO75895.1 - 7.9e-19 67.8 0.0 7.5e-15 54.7 0.0 2.1 1 1 0 2 2 2 2 Aminotransferase class I and II Armet PF10208.4 CDO75895.1 - 0.081 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Aminotran_MocR PF12897.2 CDO75895.1 - 0.19 10.2 0.0 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Polyketide_cyc PF03364.15 CDO75896.1 - 4.8e-11 42.7 0.0 5.8e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport rve PF00665.21 CDO75899.1 - 3.3e-22 78.8 0.0 5.9e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO75899.1 - 2.4e-07 30.3 0.1 4.8e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CDO75899.1 - 0.00046 19.5 0.0 0.00085 18.6 0.0 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Imm47 PF15586.1 CDO75899.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 47 TMEM247 PF15444.1 CDO75900.1 - 8.3 6.1 11.9 1.3 8.7 3.5 2.3 2 0 0 2 2 2 0 Transmembrane protein 247 Glyco_hydro_16 PF00722.16 CDO75901.1 - 1.6e-06 27.5 0.8 2.5e-06 26.9 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RUN PF02759.14 CDO75901.1 - 0.081 12.6 0.2 0.67 9.7 0.0 2.0 2 0 0 2 2 2 0 RUN domain Nudix_N_2 PF14803.1 CDO75902.1 - 1.3 8.7 6.2 0.2 11.3 0.3 2.6 2 1 0 2 2 2 0 Nudix N-terminal Glycoamylase PF10091.4 CDO75904.1 - 0.0085 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Putative glucoamylase PV-1 PF06637.6 CDO75906.1 - 0.091 11.3 7.4 0.15 10.6 5.2 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Myb_DNA-bind_4 PF13837.1 CDO75911.1 - 2.6e-09 37.1 0.1 4.9e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO75911.1 - 4.3e-07 30.4 0.1 6.8e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO75911.1 - 2.3e-05 24.1 0.1 6.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO75911.1 - 0.0017 18.3 0.1 0.0056 16.7 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CDO75911.1 - 0.0047 16.9 0.5 0.012 15.6 0.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain LAT PF15234.1 CDO75911.1 - 0.019 14.4 1.4 0.031 13.7 0.9 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells Myc_N PF01056.13 CDO75911.1 - 0.065 12.3 4.6 0.021 13.9 1.1 1.7 2 0 0 2 2 2 0 Myc amino-terminal region Sigma70_ner PF04546.8 CDO75911.1 - 0.13 11.8 7.7 0.04 13.5 3.3 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2890 PF11081.3 CDO75911.1 - 1.1 9.2 8.8 0.53 10.3 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) PBP1_TM PF14812.1 CDO75911.1 - 3.1 8.1 6.1 2.3 8.6 2.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 CDO75911.1 - 4.4 7.5 11.3 9.6 6.5 7.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Transposase_21 PF02992.9 CDO75913.1 - 1.5e-20 73.2 0.7 3e-20 72.3 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 CDO75913.1 - 1.6e-05 24.3 0.0 1.6e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) APH PF01636.18 CDO75914.1 - 2.2e-15 57.0 0.3 5.1e-15 55.8 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO75914.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mid1 PF12929.2 CDO75915.1 - 1.4e-14 53.6 0.1 9.6e-11 41.0 0.1 2.0 2 0 0 2 2 2 2 Stretch-activated Ca2+-permeable channel component APH PF01636.18 CDO75916.1 - 6.4e-15 55.5 0.2 9.8e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO75916.1 - 0.0052 16.3 0.0 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Proteasome PF00227.21 CDO75918.1 - 1.2e-47 161.7 0.0 1.5e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CDO75918.1 - 2.6e-12 45.7 0.3 5.2e-12 44.8 0.2 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal BAR_2 PF10455.4 CDO75919.1 - 2.4e-48 164.5 1.8 1e-47 162.4 1.2 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 CDO75919.1 - 2e-14 53.6 4.2 2.5e-13 50.0 2.9 2.0 1 1 0 1 1 1 1 BAR domain Holin_LLH PF09682.5 CDO75919.1 - 0.87 9.7 5.3 0.9 9.6 0.0 2.6 1 1 0 2 2 2 0 Phage holin protein (Holin_LLH) F-box-like PF12937.2 CDO75920.1 - 0.0086 15.7 3.6 0.024 14.3 0.6 3.0 2 1 0 2 2 2 1 F-box-like adh_short PF00106.20 CDO75921.1 - 1.5e-12 47.7 1.4 6.1e-12 45.7 0.9 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO75921.1 - 2.6e-06 27.4 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CDO75921.1 - 2.8e-06 26.9 0.0 4.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CDO75921.1 - 0.0026 17.4 0.0 0.0076 15.9 0.0 1.8 2 0 0 2 2 2 1 KR domain Aldedh PF00171.17 CDO75922.1 - 8.8e-127 423.2 0.0 9.9e-127 423.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CDO75922.1 - 7.6e-10 38.0 0.0 1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) ICMT PF04140.9 CDO75923.1 - 3.9e-16 59.0 1.0 6e-15 55.2 0.1 2.7 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO75923.1 - 1.6e-09 37.7 1.1 9.8e-09 35.2 0.1 2.4 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO75923.1 - 2.3e-08 32.9 0.2 3.3e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MFS_1 PF07690.11 CDO75924.1 - 2.8e-15 55.9 29.2 2.8e-15 55.9 20.2 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF939 PF06081.6 CDO75924.1 - 0.12 12.2 6.0 16 5.3 0.2 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF939) ICMT PF04140.9 CDO75925.1 - 1.3e-13 50.9 2.8 3.5e-13 49.5 0.1 2.6 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO75925.1 - 1.6e-08 34.6 0.6 1.6e-08 34.6 0.4 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO75925.1 - 1.2e-07 30.7 0.2 1.7e-07 30.1 0.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ASXH PF13919.1 CDO75926.1 - 5.6e-14 52.1 0.0 1.2e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Asx homology domain P_C PF06640.6 CDO75926.1 - 0.59 10.0 7.3 8.4 6.3 2.4 2.4 2 0 0 2 2 2 0 P protein C-terminus Cellulase PF00150.13 CDO75930.1 - 5.3e-33 114.4 1.1 8.5e-33 113.7 0.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 CDO75931.1 - 1.9e-32 112.6 2.5 2.7e-32 112.0 1.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RNase_PH PF01138.16 CDO75932.1 - 2.3e-18 66.7 0.0 3.5e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_M24 PF00557.19 CDO75933.1 - 7.2e-57 192.3 0.0 1e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CDO75933.1 - 1.9e-18 66.1 0.0 3.5e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain CBS PF00571.23 CDO75934.1 - 7.3e-05 22.4 0.3 7.4 6.4 0.0 4.1 3 0 0 3 3 3 3 CBS domain DUF21 PF01595.15 CDO75934.1 - 0.035 13.3 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF21 CDC45 PF02724.9 CDO75934.1 - 3 5.7 6.4 4.3 5.2 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nse4_C PF08743.5 CDO75935.1 - 6.7e-26 90.1 0.0 1.3e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 CDO75935.1 - 4.8e-16 58.3 0.1 1.2e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF948 PF06103.6 CDO75935.1 - 0.0068 16.2 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Chloroplast_duf PF14476.1 CDO75935.1 - 0.049 12.4 0.8 0.078 11.7 0.6 1.2 1 0 0 1 1 1 0 Petal formation-expressed GTPase_Cys_C PF12631.2 CDO75935.1 - 0.07 13.5 0.4 0.13 12.7 0.3 1.4 1 0 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE CK2S PF15011.1 CDO75935.1 - 0.083 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate Peptidase_C12 PF01088.16 CDO75937.1 - 2.1e-35 121.8 0.0 2.7e-33 114.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CBFD_NFYB_HMF PF00808.18 CDO75939.1 - 8.8e-17 60.9 1.1 1.4e-16 60.2 0.8 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CDO75939.1 - 7.9e-09 35.5 0.6 1.2e-08 34.9 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ORC6 PF05460.8 CDO75939.1 - 0.017 14.2 0.6 0.018 14.1 0.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pox_Ag35 PF03286.9 CDO75939.1 - 0.051 13.0 11.4 0.083 12.4 7.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.17 CDO75939.1 - 0.072 12.0 1.5 0.087 11.8 1.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 CDO75939.1 - 0.13 11.6 10.6 0.14 11.5 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TAFII28 PF04719.9 CDO75939.1 - 0.23 11.2 1.5 0.39 10.5 1.0 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region U79_P34 PF03064.11 CDO75939.1 - 0.48 9.9 12.7 0.69 9.3 8.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDHD PF02862.12 CDO75939.1 - 0.52 10.0 2.5 0.62 9.8 1.8 1.3 1 0 0 1 1 1 0 DDHD domain Prothymosin PF03247.9 CDO75939.1 - 1.1 9.4 28.1 2.3 8.3 19.5 1.6 1 0 0 1 1 1 0 Prothymosin/parathymosin family RR_TM4-6 PF06459.7 CDO75939.1 - 1.7 8.4 7.9 2.1 8.1 5.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Adeno_terminal PF02459.10 CDO75939.1 - 2 6.4 8.3 2.7 6.0 5.8 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein RNA_pol_3_Rpc31 PF11705.3 CDO75939.1 - 3.3 7.5 18.2 5.9 6.7 12.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sld5 PF05916.6 CDO75940.1 - 5.1e-05 23.5 0.3 5.1e-05 23.5 0.2 2.3 2 1 1 3 3 3 1 GINS complex protein Glyco_hydro_61 PF03443.9 CDO75941.1 - 8.3e-53 179.4 0.5 1.2e-52 178.8 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 FAD_binding_3 PF01494.14 CDO75942.1 - 5.7e-19 68.3 5.9 4.4e-17 62.1 4.1 2.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CDO75942.1 - 2.5e-05 23.3 0.1 4.7e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDO75942.1 - 0.00036 20.4 0.1 0.00089 19.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDO75942.1 - 0.0036 17.1 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CDO75942.1 - 0.0074 15.1 0.2 0.025 13.4 0.1 1.8 1 1 0 2 2 2 1 FAD binding domain SE PF08491.5 CDO75942.1 - 0.027 13.3 0.1 0.22 10.3 0.0 2.1 1 1 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.22 CDO75942.1 - 0.072 13.5 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDO75942.1 - 0.12 11.3 0.0 0.93 8.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Glyco_hydro_61 PF03443.9 CDO75943.1 - 3.1e-58 197.1 0.1 3.1e-58 197.1 0.1 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 TFIIA PF03153.8 CDO75943.1 - 0.25 11.2 12.0 0.43 10.4 8.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM196 PF15265.1 CDO75943.1 - 9.5 5.3 26.4 13 4.8 18.3 1.1 1 0 0 1 1 1 0 FAM196 family HMG_box_2 PF09011.5 CDO75944.1 - 0.016 15.5 0.1 0.016 15.5 0.1 2.3 2 0 0 2 2 2 0 HMG-box domain DUF1509 PF07420.6 CDO75947.1 - 0.013 14.7 1.4 0.015 14.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) APH PF01636.18 CDO75948.1 - 0.017 14.8 0.1 0.95 9.1 0.0 2.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RVT_1 PF00078.22 CDO75949.1 - 2.8e-23 82.3 0.0 3.4e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO75950.1 - 3.9e-13 49.8 0.0 9.6e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO75950.1 - 0.041 14.2 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase FKBP_C PF00254.23 CDO75951.1 - 4.1e-34 116.4 0.0 5.2e-34 116.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FCH PF00611.18 CDO75954.1 - 9.2e-18 64.2 0.5 2.1e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Asp_Glu_race PF01177.17 CDO75955.1 - 2.4e-21 76.6 0.0 3.1e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF2749 PF10907.3 CDO75955.1 - 0.11 12.3 0.7 0.29 11.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Abhydrolase_4 PF08386.5 CDO75956.1 - 9e-05 22.3 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 CDO75956.1 - 0.00087 19.2 0.5 0.0018 18.1 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CDO75957.1 - 3.7e-08 33.2 0.0 7.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 CDO75957.1 - 3e-05 23.9 0.1 5.2e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO75957.1 - 0.0017 17.9 0.0 0.0055 16.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.6 CDO75958.1 - 1.1e-22 80.7 8.0 2.5e-20 73.0 1.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PseudoU_synth_2 PF00849.17 CDO75959.1 - 4.8e-15 55.7 0.0 6.8e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase MFS_1 PF07690.11 CDO75960.1 - 1.3e-30 106.3 20.5 2.6e-30 105.3 14.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO75960.1 - 4.5e-08 32.1 4.3 1.7e-07 30.2 3.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 CDO75960.1 - 2.3e-05 23.0 13.0 0.0022 16.4 0.4 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 CDO75960.1 - 5.2e-05 21.6 0.3 5.2e-05 21.6 0.2 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Beta-lactamase PF00144.19 CDO75962.1 - 6.4e-30 104.2 0.9 2.7e-29 102.2 0.6 1.9 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 CDO75962.1 - 0.09 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Dispanin PF04505.7 CDO75963.1 - 0.083 12.4 0.0 0.32 10.5 0.0 2.1 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Ank_5 PF13857.1 CDO75964.1 - 3e-08 33.6 0.2 0.0001 22.4 0.1 3.5 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CDO75964.1 - 1.3e-06 28.6 0.0 0.00064 20.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDO75964.1 - 1.7e-06 28.3 0.4 0.055 14.0 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO75964.1 - 4.9e-06 26.2 0.1 0.043 14.0 0.0 4.0 2 1 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 CDO75964.1 - 6.9e-06 25.6 0.1 0.00029 20.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat FlgD_ig PF13860.1 CDO75964.1 - 0.00085 19.0 0.7 0.0021 17.7 0.1 1.9 2 0 0 2 2 2 1 FlgD Ig-like domain Uso1_p115_head PF04869.9 CDO75965.1 - 1.2e-41 142.5 0.0 1.4e-30 106.1 0.0 3.5 3 0 0 3 3 3 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 CDO75965.1 - 5.6e-10 39.2 17.8 1e-09 38.4 12.3 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Seryl_tRNA_N PF02403.17 CDO75965.1 - 0.0064 16.4 5.2 0.02 14.9 3.6 1.9 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Cnd1 PF12717.2 CDO75965.1 - 0.0067 16.2 2.6 0.018 14.9 0.1 2.7 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Laminin_II PF06009.7 CDO75965.1 - 0.011 15.4 5.4 0.023 14.4 3.8 1.4 1 0 0 1 1 1 0 Laminin Domain II RIX1 PF08167.7 CDO75965.1 - 0.011 15.3 0.2 0.36 10.4 0.0 3.1 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis HEAT_2 PF13646.1 CDO75965.1 - 0.014 15.6 10.4 0.017 15.3 0.0 4.4 3 1 2 5 5 4 0 HEAT repeats RmuC PF02646.11 CDO75965.1 - 0.018 13.9 2.5 0.033 13.0 1.7 1.3 1 0 0 1 1 1 0 RmuC family Atg14 PF10186.4 CDO75965.1 - 0.03 13.2 4.2 0.047 12.6 2.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HEAT_EZ PF13513.1 CDO75965.1 - 0.065 13.7 3.4 1.6 9.3 0.0 3.8 3 0 0 3 3 2 0 HEAT-like repeat IncA PF04156.9 CDO75965.1 - 0.13 11.8 7.7 0.32 10.5 5.4 1.6 1 0 0 1 1 1 0 IncA protein Adaptin_N PF01602.15 CDO75965.1 - 0.19 10.0 4.4 5.5 5.1 0.0 2.8 2 1 1 3 3 3 0 Adaptin N terminal region Retrotrans_gag PF03732.12 CDO75965.1 - 0.22 11.5 0.9 0.73 9.9 0.4 2.0 2 0 0 2 2 1 0 Retrotransposon gag protein NPV_P10 PF05531.7 CDO75965.1 - 0.56 10.4 4.2 1.5 9.0 2.9 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3373 PF11853.3 CDO75965.1 - 1.4 7.3 2.0 2.1 6.7 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) V_ATPase_I PF01496.14 CDO75965.1 - 1.8 6.3 9.8 4.7 4.9 6.9 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 CDO75965.1 - 1.9 8.8 7.3 5.3 7.4 5.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 CDO75965.1 - 2.5 7.6 13.0 5.2 6.6 0.8 3.1 3 1 1 4 4 2 0 Septum formation initiator FlxA PF14282.1 CDO75965.1 - 2.7 7.9 10.1 48 3.9 6.9 2.5 2 1 0 2 2 1 0 FlxA-like protein SlyX PF04102.7 CDO75965.1 - 4.4 7.7 14.3 0.47 10.8 0.6 2.9 2 1 1 3 3 2 0 SlyX HEAT PF02985.17 CDO75965.1 - 4.9 7.5 9.3 32 4.9 0.0 5.0 6 0 0 6 6 4 0 HEAT repeat Mo25 PF08569.6 CDO75965.1 - 6.5 5.6 9.2 0.27 10.2 0.3 2.6 2 1 0 2 2 2 0 Mo25-like BTV_NS2 PF04514.7 CDO75965.1 - 8.5 5.1 13.6 12 4.6 9.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Aminotran_5 PF00266.14 CDO75966.1 - 1.2e-29 103.2 0.0 1.8e-28 99.3 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Amelogenin PF02948.10 CDO75966.1 - 0.04 14.5 0.0 0.066 13.8 0.0 1.2 1 0 0 1 1 1 0 Amelogenin Beta_elim_lyase PF01212.16 CDO75966.1 - 0.076 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cwf_Cwc_15 PF04889.7 CDO75967.1 - 9.6e-76 254.7 26.4 1.1e-75 254.5 18.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF506 PF04720.7 CDO75967.1 - 0.089 12.4 7.9 0.15 11.7 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF506) CDC45 PF02724.9 CDO75967.1 - 0.12 10.3 19.8 0.15 10.0 13.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Sin_N PF04801.8 CDO75967.1 - 1.2 7.9 10.2 2 7.2 7.1 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region Nop14 PF04147.7 CDO75967.1 - 1.3 6.8 32.3 1.6 6.5 22.4 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CDO75967.1 - 1.6 7.1 28.1 2 6.8 19.5 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 CDO75967.1 - 1.8 7.0 10.4 2.1 6.9 7.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.7 CDO75967.1 - 2.8 6.2 28.4 3.7 5.8 19.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Merozoite_SPAM PF07133.6 CDO75967.1 - 3.1 7.6 28.1 0.95 9.3 17.5 1.6 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Rhabdo_ncap PF00945.13 CDO75967.1 - 3.8 6.0 10.2 5.4 5.4 7.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein HNF-1_N PF04814.8 CDO75967.1 - 8.2 6.4 14.1 17 5.4 9.7 1.7 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus SDA1 PF05285.7 CDO75967.1 - 9.7 5.3 35.9 14 4.8 24.6 1.4 1 1 0 1 1 1 0 SDA1 Saccharop_dh PF03435.13 CDO75968.1 - 7e-19 68.0 0.0 9.8e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CDO75968.1 - 2.1e-08 34.3 0.0 3.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CDO75968.1 - 2.7e-05 23.7 0.0 4.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO75968.1 - 0.00057 18.6 0.0 0.00082 18.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CDO75968.1 - 0.0012 19.1 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CDO75968.1 - 0.0031 17.4 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 CDO75968.1 - 0.01 15.4 0.1 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 CDO75968.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 CDO75968.1 - 0.023 13.9 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Saccharop_dh PF03435.13 CDO75969.1 - 2e-19 69.8 0.1 2.5e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CDO75969.1 - 6.2e-08 32.8 0.1 9.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CDO75969.1 - 7.7e-08 32.0 0.1 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CDO75969.1 - 8.8e-06 26.0 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 CDO75969.1 - 9.9e-05 21.7 0.1 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 CDO75969.1 - 0.00061 18.5 0.0 0.00086 18.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CDO75969.1 - 0.0029 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO75969.1 - 0.003 17.2 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.15 CDO75969.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 CDO75969.1 - 0.036 13.0 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DUF1479 PF07350.7 CDO75970.1 - 1.6e-132 441.9 0.0 1.4e-120 402.5 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) IKI3 PF04762.7 CDO75971.1 - 1.8e-242 807.1 0.0 1.7e-185 618.5 0.0 2.4 1 1 1 2 2 2 2 IKI3 family TPR_12 PF13424.1 CDO75971.1 - 0.0067 16.3 1.7 1.6 8.7 0.4 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat Clathrin PF00637.15 CDO75971.1 - 0.023 14.2 2.9 1.5 8.3 0.0 3.9 2 1 2 4 4 4 0 Region in Clathrin and VPS TMF_TATA_bd PF12325.3 CDO75971.1 - 0.096 12.4 2.4 0.41 10.3 0.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4404 PF14357.1 CDO75971.1 - 1.6 9.2 5.8 14 6.1 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DDE_1 PF03184.14 CDO75972.1 - 1.5e-33 115.7 0.0 2.7e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CDO75972.1 - 5.6e-08 32.4 0.4 1.7e-07 30.9 0.3 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain YLP PF02757.12 CDO75973.1 - 0.11 12.1 0.2 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 YLP motif Transposase_21 PF02992.9 CDO75975.1 - 4.7e-15 55.2 0.3 1.6e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 Transposase family tnp2 TOBE_2 PF08402.5 CDO75975.1 - 0.039 13.9 0.5 0.37 10.8 0.0 2.7 2 0 0 2 2 2 0 TOBE domain WD40 PF00400.27 CDO75976.1 - 2.2e-22 78.0 5.7 3.9e-09 36.0 0.2 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Ras PF00071.17 CDO75977.1 - 3.2e-55 185.9 0.0 3.7e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO75977.1 - 1.3e-15 57.9 0.0 1.7e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO75977.1 - 7.5e-07 28.5 0.0 1.2e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CDO75977.1 - 0.0025 17.0 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CDO75977.1 - 0.052 12.6 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CDO75977.1 - 0.1 12.0 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AKAP7_NLS PF10469.4 CDO75978.1 - 2.7e-21 76.2 0.0 5.9e-21 75.1 0.0 1.5 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Asp PF00026.18 CDO75979.1 - 3.7e-17 62.5 0.0 8.7e-15 54.7 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease rve PF00665.21 CDO75981.1 - 3.3e-18 65.9 0.0 5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CDO75981.1 - 0.0065 15.8 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger IGPD PF00475.13 CDO75981.1 - 0.034 13.9 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase Imm47 PF15586.1 CDO75981.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 47 RVT_1 PF00078.22 CDO75982.1 - 6.8e-23 81.1 0.0 1.2e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO75982.1 - 0.019 13.9 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2_4 PF13894.1 CDO75983.1 - 1.3 9.4 6.9 3.6 8.1 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger TFIIS_M PF07500.9 CDO75985.1 - 4.5e-15 55.7 3.1 9.5e-15 54.6 2.2 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 CDO75985.1 - 8.7e-09 34.9 4.4 1.6e-08 34.0 3.1 1.4 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 CDO75985.1 - 0.00038 20.9 0.0 0.00094 19.6 0.0 1.7 1 0 0 1 1 1 1 SPOC domain zf-HC5HC2H PF13771.1 CDO75985.1 - 0.049 13.7 0.6 0.11 12.7 0.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CDO75985.1 - 0.15 12.1 0.5 0.28 11.2 0.3 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Abhydrolase_3 PF07859.8 CDO75986.1 - 4.5e-24 85.1 0.0 6.7e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CDO75986.1 - 1.1e-09 37.4 0.0 1.4e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 CDO75986.1 - 4.6e-05 23.4 0.6 7.7e-05 22.6 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO75986.1 - 0.0023 17.6 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CDO75986.1 - 0.012 14.3 0.5 1.1 7.8 0.0 2.5 2 0 0 2 2 2 0 Carboxylesterase family p450 PF00067.17 CDO75988.1 - 1.6e-63 214.8 0.0 9.2e-63 212.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 p450 PF00067.17 CDO75989.1 - 4.5e-66 223.2 0.0 9e-66 222.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 CDO75991.1 - 1.1e-23 83.9 0.0 2.6e-21 76.1 0.0 2.9 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CDO75991.1 - 3.5e-06 27.4 1.5 8.1e-05 23.0 0.2 3.0 2 1 0 2 2 2 1 Aspartyl protease Ferritin_2 PF13668.1 CDO75992.1 - 1.7e-25 89.5 0.9 3.4e-25 88.5 0.2 1.7 2 0 0 2 2 2 1 Ferritin-like domain DUF768 PF05589.6 CDO75992.1 - 0.11 12.5 0.4 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF768) DUF4449 PF14613.1 CDO75993.1 - 1.3e-25 90.2 0.1 1.3e-25 90.2 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) RVT_1 PF00078.22 CDO75994.1 - 2.4e-20 72.8 0.0 4.3e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO75994.1 - 1.5e-14 54.4 0.0 3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 CDO75994.1 - 4.4e-08 32.7 0.1 9.4e-08 31.6 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CDO75994.1 - 0.0048 16.8 1.2 0.013 15.4 0.8 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 CDO75994.1 - 0.0055 17.0 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HUN PF08729.5 CDO75995.1 - 7.5e-10 38.5 0.1 1.9e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 CDO75995.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.1 2 1 0 2 2 2 0 Ubinuclein conserved middle domain CAF-1_p150 PF11600.3 CDO75995.1 - 1.7 7.9 8.9 0.065 12.6 1.1 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Lipase_GDSL_2 PF13472.1 CDO75996.1 - 6.2e-11 42.7 0.5 7.5e-11 42.4 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CDO75996.1 - 1.2e-07 31.7 0.2 7.5e-07 29.2 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 CDO75996.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family La PF05383.12 CDO75997.1 - 7.5e-19 67.2 0.0 1.3e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 CDO75997.1 - 7.7e-08 31.8 0.1 1.9e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO75997.1 - 4.8e-06 26.4 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1330 PF07045.6 CDO75997.1 - 0.044 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) Fungal_trans PF04082.13 CDO75998.1 - 3.2e-12 45.8 0.4 6.2e-12 44.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CDO75998.1 - 2.4e-07 30.5 7.6 5.8e-07 29.3 5.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 CDO75999.1 - 3.4e-10 38.9 0.1 3.4e-10 38.9 0.1 3.2 5 0 0 5 5 5 1 Histone chaperone domain CHZ Mating_C PF12737.2 CDO75999.1 - 0.053 12.3 13.7 0.068 12.0 9.5 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 DUF4551 PF15087.1 CDO75999.1 - 0.63 8.3 5.2 0.67 8.2 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RAP1 PF07218.6 CDO75999.1 - 1.5 6.7 12.3 1.7 6.6 8.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DHHW PF14286.1 CDO75999.1 - 5.9 6.0 11.0 5.7 6.1 7.2 1.4 1 1 0 1 1 1 0 DHHW protein Rgp1 PF08737.5 CDO75999.1 - 8.5 5.3 12.0 13 4.6 8.3 1.3 1 0 0 1 1 1 0 Rgp1 ACOX PF01756.14 CDO76000.1 - 1.3e-20 73.5 0.0 7.8e-20 71.0 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CDO76000.1 - 6.3e-20 71.7 0.0 1.2e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CDO76000.1 - 1e-08 34.5 0.6 5.7e-08 32.1 0.2 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CDO76000.1 - 0.0002 21.4 1.3 0.00067 19.7 0.4 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Ank_2 PF12796.2 CDO76001.1 - 5.2e-50 167.7 2.0 8.7e-16 58.0 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CDO76001.1 - 3.3e-39 130.7 5.7 1.1e-07 31.2 0.1 7.1 7 0 0 7 7 7 5 Ankyrin repeat zf-DHHC PF01529.15 CDO76001.1 - 6.3e-38 129.8 4.7 6.3e-38 129.8 3.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 CDO76001.1 - 4.3e-31 106.2 7.6 7.7e-12 45.0 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDO76001.1 - 7.8e-31 105.9 0.9 5.7e-10 39.4 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO76001.1 - 8.7e-25 84.3 1.1 0.00041 20.3 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Cupin_1 PF00190.17 CDO76001.1 - 7.8e-09 35.1 0.0 1.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 CDO76001.1 - 0.00018 20.9 0.0 0.00018 20.9 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 CDO76001.1 - 0.016 14.5 0.0 0.068 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) stn_TNFRSF12A PF12191.3 CDO76001.1 - 0.043 13.8 0.8 0.094 12.7 0.6 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Cupin_1 PF00190.17 CDO76002.1 - 1.1e-21 76.7 0.0 2.3e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 CDO76002.1 - 3.4e-18 64.8 0.1 5.8e-08 32.1 0.0 3.0 2 1 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 CDO76002.1 - 3.8e-05 23.3 0.4 0.0016 18.1 0.0 2.7 2 1 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.7 CDO76002.1 - 0.00016 20.9 0.0 0.003 16.9 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF861) 3-HAO PF06052.7 CDO76002.1 - 0.12 11.7 0.0 0.53 9.6 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase EF1G PF00647.14 CDO76003.1 - 7.1e-44 147.9 0.0 1.2e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 CDO76003.1 - 8.9e-14 51.4 0.0 8.9e-14 51.4 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CDO76003.1 - 5.8e-10 39.0 0.0 1.6e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO76003.1 - 2.5e-09 36.9 0.0 8e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CDO76003.1 - 1.2e-08 34.9 0.0 2.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CDO76003.1 - 1.6e-07 31.7 0.0 4.4e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CDO76003.1 - 0.00097 19.0 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 CDO76003.1 - 0.032 14.6 7.2 0.081 13.3 5.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein E1-E2_ATPase PF00122.15 CDO76004.1 - 1.7e-22 79.6 0.0 1.7e-22 79.6 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CDO76004.1 - 2.1e-16 60.9 0.0 1.3e-15 58.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDO76004.1 - 4.1e-11 43.4 0.1 8.9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDO76004.1 - 1.8e-06 27.7 0.0 9.6e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CDO76004.1 - 0.00014 21.5 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NST1 PF13945.1 CDO76005.1 - 6e-60 202.5 0.5 6e-60 202.5 0.4 4.0 2 1 2 4 4 4 1 Salt tolerance down-regulator TFIIA PF03153.8 CDO76005.1 - 0.00013 22.0 8.8 0.00013 22.0 6.1 4.3 2 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.8 CDO76006.1 - 0.91 9.1 2.7 0.47 10.0 0.2 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.1 CDO76006.1 - 9.2 6.6 8.8 2.3 8.6 1.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SSURE PF11966.3 CDO76008.1 - 0.026 14.1 0.2 4.7 6.8 0.0 2.5 1 1 1 2 2 2 0 Fibronectin-binding repeat Hist_deacetyl PF00850.14 CDO76009.1 - 3.3e-96 322.2 0.0 5.2e-96 321.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 CDO76009.1 - 2.1e-21 76.1 0.0 3.2e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain OSCP PF00213.13 CDO76010.1 - 3.4e-38 131.1 0.8 3.9e-38 130.9 0.6 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit GPAT_N PF14829.1 CDO76010.1 - 0.098 12.3 0.1 3.7 7.3 0.0 2.7 2 1 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal TRP PF06011.7 CDO76011.1 - 4.6e-68 229.7 27.7 1.1e-67 228.4 19.2 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CDO76011.1 - 4.4e-27 94.8 0.4 7e-27 94.1 0.3 1.3 1 0 0 1 1 1 1 ML-like domain UDPGP PF01704.13 CDO76013.1 - 7.1e-182 604.5 1.4 8.2e-182 604.3 0.9 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ribosomal_S8e PF01201.17 CDO76014.1 - 3.4e-45 153.4 0.4 4.8e-45 152.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e TraF PF13728.1 CDO76014.1 - 0.057 12.8 1.8 0.085 12.3 1.3 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein SET PF00856.23 CDO76015.1 - 1.5e-08 35.1 4.0 1.8e-08 34.8 0.0 3.2 2 2 0 2 2 2 1 SET domain AT_hook PF02178.14 CDO76015.1 - 0.00043 19.6 15.2 0.049 13.3 0.9 3.6 2 0 0 2 2 2 2 AT hook motif Cpn60_TCP1 PF00118.19 CDO76016.1 - 1.4e-142 475.7 0.6 1.1e-140 469.4 0.4 2.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family EthD PF07110.6 CDO76017.1 - 1.2e-12 48.5 0.1 1.6e-12 48.1 0.1 1.2 1 0 0 1 1 1 1 EthD domain EthD PF07110.6 CDO76018.1 - 4.9e-14 53.0 0.1 6e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 EthD domain PC_rep PF01851.17 CDO76019.1 - 2.3e-05 24.3 16.1 0.9 9.9 0.0 5.7 6 0 0 6 6 6 4 Proteasome/cyclosome repeat DUF2874 PF11396.3 CDO76019.1 - 0.35 10.8 0.0 0.79 9.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) Apc1 PF12859.2 CDO76020.1 - 1.8e-10 40.9 0.0 1.8e-10 40.9 0.0 3.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 1 adh_short_C2 PF13561.1 CDO76021.1 - 2.6e-21 76.5 0.1 3e-13 50.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO76021.1 - 5.2e-20 72.0 0.2 8.3e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO76021.1 - 4.5e-11 42.7 0.1 6.3e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 CDO76021.1 - 0.02 15.2 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 CDO76021.1 - 0.05 13.4 0.2 0.42 10.4 0.1 2.2 1 1 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.1 CDO76022.1 - 2e-13 50.1 0.7 5.4e-13 48.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO76022.1 - 3.4e-07 29.4 0.1 6.3e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CDO76022.1 - 3.4e-05 23.8 0.1 0.0018 18.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO76022.1 - 4.3e-05 23.3 1.7 0.00013 21.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 CDO76022.1 - 5e-05 22.5 0.0 8.7e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 CDO76022.1 - 5.8e-05 22.1 0.2 8.7e-05 21.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CDO76022.1 - 0.00015 21.9 0.2 0.00031 20.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO76022.1 - 0.00059 18.4 0.2 0.0032 15.9 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 CDO76022.1 - 0.0017 17.4 0.1 0.0017 17.4 0.1 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CDO76022.1 - 0.021 13.9 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 CDO76022.1 - 0.038 14.3 0.1 0.54 10.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CDO76022.1 - 0.077 11.8 0.3 0.12 11.1 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 CDO76022.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 CDO76023.1 - 1.1e-21 77.4 0.1 1.6e-21 76.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO76023.1 - 2.4e-10 40.3 0.1 3.5e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CDO76023.1 - 3.4e-05 23.7 0.0 5.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CDO76023.1 - 5.2e-05 23.3 0.0 8.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CDO76023.1 - 0.00058 19.3 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CDO76023.1 - 0.0013 17.6 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADSL_C PF10397.4 CDO76023.1 - 0.12 12.4 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus FKBP_C PF00254.23 CDO76024.1 - 1.2e-31 108.5 0.0 4.3e-31 106.7 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PGC7_Stella PF15549.1 CDO76024.1 - 0.042 13.8 12.0 0.028 14.3 5.6 2.0 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Hex_IIIa PF02455.11 CDO76024.1 - 1.7 7.2 6.0 1.9 7.0 4.2 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) ARPC4 PF05856.7 CDO76025.1 - 1.5e-75 252.2 5.2 1.7e-75 252.1 3.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) COesterase PF00135.23 CDO76026.1 - 2.5e-76 257.5 0.0 3.6e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CDO76026.1 - 5.7e-08 32.5 0.0 2.4e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO76026.1 - 0.0045 16.7 0.1 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO76026.1 - 0.0085 15.9 0.0 0.14 12.0 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO76026.1 - 0.048 13.2 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Scs3p PF10261.4 CDO76027.1 - 1.3e-39 135.6 4.9 4.3e-39 133.9 3.4 1.8 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM COX15-CtaA PF02628.10 CDO76027.1 - 0.21 10.4 7.5 0.078 11.8 1.9 2.0 1 1 0 2 2 2 0 Cytochrome oxidase assembly protein Ribosomal_L14e PF01929.12 CDO76028.1 - 3.7e-19 68.8 1.4 6.3e-19 68.0 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 Fungal_trans PF04082.13 CDO76030.1 - 2.7e-13 49.3 0.3 5.1e-13 48.4 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CDO76030.1 - 3.7e-07 29.9 12.6 7e-07 29.0 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.13 CDO76030.1 - 0.013 14.6 1.3 0.035 13.3 0.9 1.7 1 0 0 1 1 1 0 Copper fist DNA binding domain Glyco_hydro_18 PF00704.23 CDO76031.1 - 3.5e-63 214.1 7.0 4.6e-63 213.7 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF187 PF02638.10 CDO76031.1 - 0.00033 19.6 0.0 0.00054 18.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 RVT_2 PF07727.9 CDO76033.1 - 6.9e-05 21.9 0.0 9.5e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO76034.1 - 2.2e-82 275.7 0.0 3.3e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_2 PF14227.1 CDO76034.1 - 2.7e-16 59.1 0.1 4.6e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO76034.1 - 1.4e-13 50.6 0.1 5.1e-13 48.8 0.1 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO76034.1 - 9.3e-13 47.6 0.1 6.6e-12 44.8 0.0 2.4 2 0 0 2 2 2 1 GAG-pre-integrase domain DUF4219 PF13961.1 CDO76034.1 - 1.7e-07 30.5 0.0 3.6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 CDO76034.1 - 1.2e-06 28.1 0.0 3.4e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type rve PF00665.21 CDO76034.1 - 0.0004 20.4 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF1759 PF03564.10 CDO76034.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) zf-CCHC_4 PF14392.1 CDO76034.1 - 0.13 11.9 1.4 0.94 9.2 1.8 1.9 2 0 0 2 2 2 0 Zinc knuckle rve PF00665.21 CDO76035.1 - 4.7e-28 97.7 0.0 9.4e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 CDO76035.1 - 2.3e-14 52.9 0.0 4.4e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO76035.1 - 2e-09 37.2 0.0 3.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO76035.1 - 3.7e-09 36.0 0.1 8.8e-09 34.8 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CDO76035.1 - 3.6e-05 23.2 0.1 7.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DEAD PF00270.24 CDO76036.1 - 6.1e-14 51.8 0.0 1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO76036.1 - 5.2e-13 48.6 0.1 3.2e-12 46.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF572 PF04502.8 CDO76036.1 - 3 6.9 19.2 0.71 9.0 11.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) PLRV_ORF5 PF01690.12 CDO76036.1 - 4.5 6.3 10.1 7.5 5.5 7.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein rve PF00665.21 CDO76039.1 - 4.4e-12 46.1 0.0 9.4e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO76039.1 - 3.5e-09 36.2 0.5 7.2e-09 35.1 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CDO76040.1 - 4.1e-20 72.0 0.1 9.6e-20 70.8 0.1 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO76041.1 - 1.7e-88 295.7 0.0 2.4e-88 295.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CDO76041.1 - 0.0012 18.2 0.1 0.027 13.8 0.1 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO76042.1 - 2.8e-89 298.3 0.0 3.9e-89 297.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CDO76042.1 - 0.032 13.5 0.0 0.52 9.6 0.0 2.4 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FRQ PF09421.5 CDO76042.1 - 0.033 11.9 0.1 0.048 11.4 0.1 1.2 1 0 0 1 1 1 0 Frequency clock protein DSPc PF00782.15 CDO76043.1 - 6.3e-07 29.0 0.0 9.1e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CDO76043.1 - 2.4e-05 24.6 0.2 0.011 16.0 0.1 2.3 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 CDO76043.1 - 2.6e-05 23.6 0.0 3.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CDO76043.1 - 3.2e-05 23.4 0.0 4.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 CDO76043.1 - 0.00069 19.6 0.0 0.0014 18.7 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Amidohydro_4 PF13147.1 CDO76044.1 - 4.6e-18 66.2 4.8 6e-17 62.5 0.0 3.7 2 2 1 3 3 3 1 Amidohydrolase Amidohydro_5 PF13594.1 CDO76044.1 - 7.3e-14 51.3 2.2 1.5e-08 34.2 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 CDO76044.1 - 1.4e-08 34.8 0.4 1.5e-06 28.0 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_3 PF07969.6 CDO76044.1 - 9.4e-07 28.3 0.3 2.1e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase family Pkinase PF00069.20 CDO76045.1 - 3.5e-62 209.9 0.0 2e-32 112.3 0.0 4.6 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76045.1 - 5.2e-29 101.0 0.0 8.7e-13 47.9 0.0 4.3 3 1 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 CDO76045.1 - 1.3e-24 86.8 1.5 1.4e-23 83.3 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.1 CDO76045.1 - 1.7e-13 50.3 1.5 3.4e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 CDO76045.1 - 9.9e-12 44.7 0.8 5.7e-11 42.3 0.0 2.6 2 0 0 2 2 2 1 RWD domain APH PF01636.18 CDO76045.1 - 0.0011 18.6 0.0 0.0011 18.6 0.0 2.7 4 0 0 4 4 4 1 Phosphotransferase enzyme family LysM PF01476.15 CDO76046.1 - 6.5e-09 35.5 0.1 1.6e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 LysM domain PNRC PF15365.1 CDO76047.1 - 0.02 14.8 2.6 0.047 13.7 1.8 1.6 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator Pkinase PF00069.20 CDO76048.1 - 2.3e-08 33.4 0.1 3.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76048.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.9 CDO76048.1 - 0.06 12.4 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1510 PF07423.6 CDO76048.1 - 1.5 8.1 27.9 1.9 7.7 19.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MMtag PF10159.4 CDO76050.1 - 7.6e-32 109.2 4.1 7.6e-32 109.2 2.9 3.2 3 1 0 3 3 3 1 Kinase phosphorylation protein Pol_alpha_B_N PF08418.5 CDO76050.1 - 0.57 9.6 8.1 0.82 9.1 5.6 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF936 PF06075.7 CDO76050.1 - 0.91 8.3 12.8 1.1 8.1 8.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Rtf2 PF04641.7 CDO76050.1 - 3.5 6.7 10.8 0.34 10.0 4.5 1.5 2 0 0 2 2 2 0 Rtf2 RING-finger R3H PF01424.17 CDO76051.1 - 3.4e-11 42.6 0.0 1.6e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 R3H domain Use1 PF09753.4 CDO76052.1 - 1e-12 48.0 0.0 1.2e-12 47.8 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF3753 PF12575.3 CDO76052.1 - 0.0013 18.4 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) Rhabdo_glycop PF00974.13 CDO76052.1 - 0.0067 14.7 0.2 0.0081 14.4 0.1 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein DUF912 PF06024.7 CDO76052.1 - 0.055 13.5 0.1 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tektin PF03148.9 CDO76052.1 - 0.1 11.1 4.3 0.12 10.8 3.0 1.1 1 0 0 1 1 1 0 Tektin family BicD PF09730.4 CDO76052.1 - 0.16 10.3 4.2 0.2 9.9 2.9 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Glyco_hydro_2 PF00703.16 CDO76054.1 - 1.3e-06 28.8 0.0 0.00015 22.1 0.0 3.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 CDO76054.1 - 0.0036 16.2 0.0 0.0073 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain AA_permease PF00324.16 CDO76055.1 - 1.4e-101 340.2 38.8 4.7e-90 302.2 15.0 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 CDO76055.1 - 4.4e-25 88.1 35.7 4.2e-24 84.8 15.1 2.1 1 1 1 2 2 2 2 Amino acid permease DUF2759 PF10958.3 CDO76055.1 - 0.57 9.7 7.9 0.49 10.0 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) S-methyl_trans PF02574.11 CDO76056.1 - 6.4e-32 111.0 0.0 1.2e-18 67.4 0.0 3.0 2 1 0 2 2 2 2 Homocysteine S-methyltransferase Ribosomal_S2 PF00318.15 CDO76057.1 - 1.2e-43 148.7 0.0 5.1e-22 78.1 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Glucosamine_iso PF01182.15 CDO76058.1 - 3.1e-11 43.3 0.0 5.3e-07 29.5 0.0 2.3 1 1 1 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.7 CDO76058.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain Pkinase PF00069.20 CDO76059.1 - 1.4e-63 214.4 0.0 2.2e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76059.1 - 5e-37 127.3 0.0 1e-35 123.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO76059.1 - 6.5e-06 25.3 0.0 1.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO76059.1 - 0.00057 19.6 9.8 0.014 15.1 0.2 3.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Cytochrom_B561 PF03188.11 CDO76060.1 - 1.2e-11 44.6 4.0 1.2e-11 44.6 2.8 1.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4181 PF13789.1 CDO76060.1 - 0.00011 22.0 2.1 0.0057 16.5 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4181) DUF2427 PF10348.4 CDO76060.1 - 0.00055 19.4 4.4 0.00055 19.4 3.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF4051 PF13260.1 CDO76060.1 - 0.045 13.0 0.1 0.045 13.0 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4051) DUF1290 PF06947.7 CDO76060.1 - 0.13 12.2 0.9 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1290) WBP-1 PF11669.3 CDO76060.1 - 0.14 12.2 0.3 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 WW domain-binding protein 1 Ni_hydr_CYTB PF01292.15 CDO76060.1 - 1 8.7 13.1 2.5 7.4 8.6 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 TctB PF07331.6 CDO76060.1 - 1.3 8.6 10.6 0.057 13.0 1.3 2.7 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4282 PF14110.1 CDO76060.1 - 7.2 6.8 11.7 1 9.5 0.8 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4282) 7tm_7 PF08395.7 CDO76060.1 - 9.6 5.1 8.5 10 5.0 0.6 2.2 1 1 1 2 2 2 0 7tm Chemosensory receptor Cytochrom_B561 PF03188.11 CDO76061.1 - 4.4e-11 42.7 3.9 9e-11 41.7 2.7 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 CDO76061.1 - 2.4e-06 27.4 0.1 5.6e-06 26.2 0.1 1.6 1 1 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 CDO76061.1 - 0.026 14.0 3.2 0.075 12.6 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Mg_trans_NIPA PF05653.9 CDO76062.1 - 8.1e-41 139.9 21.9 1.6e-26 92.9 4.2 3.1 3 0 0 3 3 3 3 Magnesium transporter NIPA SPC22 PF04573.7 CDO76064.1 - 5.2e-39 133.2 0.0 5.7e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Acyltransferase PF01553.16 CDO76065.1 - 1.9e-05 24.0 0.0 3.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase CobD_Cbib PF03186.8 CDO76065.1 - 0.044 12.8 1.0 0.075 12.1 0.7 1.3 1 0 0 1 1 1 0 CobD/Cbib protein PP2C PF00481.16 CDO76066.1 - 6.1e-44 150.3 0.0 8e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.15 CDO76066.1 - 2.7e-23 82.2 0.0 4.4e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.2 CDO76067.1 - 6.9e-63 207.4 43.6 9.4e-10 37.8 1.4 11.4 10 1 1 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDO76067.1 - 3.9e-54 180.2 47.1 2.9e-11 42.9 1.0 8.3 7 1 1 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 CDO76067.1 - 8.9e-32 104.2 54.7 0.0039 17.0 0.9 18.7 19 0 0 19 19 19 11 Leucine Rich Repeat LRR_7 PF13504.1 CDO76067.1 - 6e-17 58.7 50.0 1.2 9.6 0.3 17.5 18 0 0 18 18 18 5 Leucine rich repeat LRR_6 PF13516.1 CDO76067.1 - 3.9e-09 35.6 48.8 0.24 11.5 0.0 16.1 16 1 1 17 17 17 3 Leucine Rich repeat Ad_cyc_g-alpha PF08509.6 CDO76067.1 - 4.9e-06 25.7 0.4 2.1e-05 23.7 0.3 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.18 CDO76067.1 - 9.7e-06 25.9 0.0 3.9e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.1 CDO76067.1 - 2.5e-05 23.9 10.2 0.056 13.0 0.6 4.5 3 1 2 5 5 5 3 Leucine-rich repeat LRR_5 PF13306.1 CDO76067.1 - 0.00043 19.9 0.2 0.72 9.5 0.1 4.0 3 2 1 4 4 4 1 Leucine rich repeats (6 copies) rve PF00665.21 CDO76068.1 - 9.2e-18 64.4 0.0 2e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 CDO76068.1 - 0.029 13.8 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Caudal_act PF04731.7 CDO76068.1 - 0.088 13.1 0.2 0.14 12.4 0.2 1.3 1 0 0 1 1 1 0 Caudal like protein activation region RVT_1 PF00078.22 CDO76069.1 - 1e-21 77.2 0.0 2e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 CDO76069.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RicinB_lectin_2 PF14200.1 CDO76070.1 - 0.091 13.1 2.1 0.81 10.0 0.3 2.8 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like RVT_1 PF00078.22 CDO76071.1 - 1.7e-39 135.4 0.0 2.9e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO76071.1 - 9.7e-17 61.5 0.1 2.6e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 RNase H DUF445 PF04286.7 CDO76071.1 - 1.5 8.2 10.3 11 5.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF445) HTH_1 PF00126.22 CDO76072.1 - 1.2 8.9 3.6 5.1 6.9 2.5 2.1 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family UPF0118 PF01594.11 CDO76073.1 - 0.0074 15.3 1.1 0.012 14.6 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF20 DUF3112 PF11309.3 CDO76073.1 - 0.037 13.8 1.2 0.087 12.6 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) 7tm_7 PF08395.7 CDO76073.1 - 0.039 12.9 2.5 0.061 12.3 1.7 1.3 1 1 0 1 1 1 0 7tm Chemosensory receptor DUF1430 PF07242.6 CDO76073.1 - 3.6 7.7 6.6 5.5 7.1 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1430) TrbC PF04956.8 CDO76073.1 - 8.9 6.3 8.0 0.47 10.4 0.4 2.4 2 1 0 2 2 2 0 TrbC/VIRB2 family Myb_DNA-bind_3 PF12776.2 CDO76074.1 - 2.7e-05 24.7 0.4 4.8e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CDO76074.1 - 0.00021 21.3 0.4 0.00064 19.8 0.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pap_E4 PF02711.9 CDO76074.1 - 1.9 9.3 6.1 4 8.3 0.7 2.7 2 1 0 2 2 2 0 E4 protein XPG_I PF00867.13 CDO76076.1 - 2e-19 69.4 0.0 3.2e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CDO76076.1 - 2.8e-05 24.2 0.0 6.4e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CDO76076.1 - 0.077 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing GPI-anchored PF10342.4 CDO76077.1 - 4.4e-07 30.2 0.0 6.1e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CDO76077.1 - 0.04 13.4 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Kinesin PF00225.18 CDO76078.1 - 5.3e-81 271.9 0.0 5e-79 265.4 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain UPF0242 PF06785.6 CDO76078.1 - 0.53 8.9 4.2 1 7.9 2.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) GST_N_3 PF13417.1 CDO76079.1 - 6.7e-14 51.8 0.0 1.5e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO76079.1 - 1.4e-11 44.1 0.0 2.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO76079.1 - 2.3e-07 30.5 0.3 6.7e-07 29.1 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO76079.1 - 2.8e-06 27.2 0.0 4.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO76079.1 - 0.00025 21.4 0.1 0.00044 20.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CDO76079.1 - 0.001 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CDO76080.1 - 1.1e-13 51.1 0.1 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO76080.1 - 8.9e-11 41.6 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO76080.1 - 8.5e-07 28.7 1.2 1.9e-06 27.6 0.5 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO76080.1 - 0.0001 22.7 0.1 0.00024 21.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO76080.1 - 0.0012 18.8 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CDO76080.1 - 0.004 17.3 0.0 0.01 15.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CDO76081.1 - 4.9e-14 52.3 0.1 1.1e-13 51.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO76081.1 - 1.1e-11 44.6 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO76081.1 - 2.2e-06 27.4 1.2 6e-06 26.0 0.3 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO76081.1 - 1.7e-05 25.1 0.1 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO76081.1 - 0.00085 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CDO76081.1 - 0.041 14.0 0.0 0.089 12.9 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CDO76082.1 - 2.5e-14 53.2 0.1 4.9e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO76082.1 - 2e-12 46.8 0.0 3.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CDO76082.1 - 1.5e-06 28.5 0.0 2.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO76082.1 - 1.6e-06 27.9 0.3 4.5e-06 26.4 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO76082.1 - 0.00038 20.3 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CDO76082.1 - 0.021 14.9 0.0 0.05 13.7 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ERG4_ERG24 PF01222.12 CDO76083.1 - 6e-140 466.5 2.6 7.3e-140 466.3 1.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 CDO76083.1 - 2.3e-06 27.6 0.4 1.2e-05 25.4 0.0 2.5 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 CDO76083.1 - 0.00019 20.8 0.1 0.00046 19.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CDO76083.1 - 0.001 19.2 0.0 0.0042 17.2 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DMAP_binding PF06464.6 CDO76084.1 - 0.0083 16.7 0.3 0.0083 16.7 0.2 2.2 2 0 0 2 2 2 1 DMAP1-binding Domain Na_Ca_ex PF01699.19 CDO76085.1 - 1.9e-21 76.1 26.6 2.1e-13 50.0 5.9 3.8 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 CDO76085.1 - 5.8e-10 39.4 14.4 5.8e-10 39.4 10.0 3.6 2 0 0 2 2 2 1 Domain of unknown function (DUF307) CBFD_NFYB_HMF PF00808.18 CDO76086.1 - 7.9e-15 54.6 0.5 1.3e-14 53.9 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CDO76086.1 - 1.8e-07 31.1 1.4 2.9e-07 30.5 0.9 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 CDO76086.1 - 0.0016 18.1 0.1 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.11 CDO76086.1 - 0.39 10.5 2.0 0.3 10.9 0.2 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit CPSF_A PF03178.10 CDO76087.1 - 9.7e-43 146.4 0.0 2.3e-42 145.2 0.0 1.7 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 CDO76087.1 - 2.3e-41 141.5 0.0 4.1e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_2 PF13360.1 CDO76087.1 - 0.0089 15.5 0.2 0.26 10.6 0.1 2.7 2 0 0 2 2 2 1 PQQ-like domain TRAP-gamma PF07074.7 CDO76088.1 - 0.13 11.7 2.5 0.27 10.7 0.3 2.1 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Leader_Trp PF08255.6 CDO76089.1 - 2.4 8.0 6.2 35 4.3 0.1 2.8 2 0 0 2 2 2 0 Trp-operon Leader Peptide She9_MDM33 PF05546.6 CDO76090.1 - 8.7e-65 218.1 12.9 1.9e-59 200.7 7.5 2.2 2 0 0 2 2 2 2 She9 / Mdm33 family Mt_ATP-synt_B PF05405.9 CDO76090.1 - 0.14 11.6 2.8 0.3 10.5 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Pex19 PF04614.7 CDO76090.1 - 0.8 9.2 6.4 0.2 11.2 0.2 2.5 3 0 0 3 3 3 0 Pex19 protein family FAD_binding_1 PF00667.15 CDO76091.1 - 7.3e-57 192.3 0.0 5e-56 189.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CDO76091.1 - 1e-30 106.5 0.2 2.1e-30 105.5 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CDO76091.1 - 2.8e-22 79.3 0.0 1.7e-21 76.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DDE_Tnp_1_4 PF13701.1 CDO76091.1 - 0.067 11.3 0.0 0.093 10.8 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 Flavodoxin_5 PF12724.2 CDO76091.1 - 0.068 13.1 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain SET PF00856.23 CDO76092.1 - 5.6e-06 26.7 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 SET domain Yae1_N PF09811.4 CDO76093.1 - 3.4e-14 52.0 2.1 7.8e-14 50.9 1.4 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SpoIIIAH PF12685.2 CDO76093.1 - 0.03 13.8 0.4 0.036 13.5 0.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein MtrG PF04210.8 CDO76093.1 - 0.042 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Adaptin_binding PF10199.4 CDO76093.1 - 0.087 13.1 2.5 0.14 12.4 1.7 1.5 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Neurochondrin PF05536.6 CDO76093.1 - 0.089 11.0 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Neurochondrin cobW PF02492.14 CDO76094.1 - 2.7e-27 95.3 0.5 1.7e-26 92.7 0.3 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 CDO76094.1 - 3.4e-06 26.6 0.0 6.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain DSPc PF00782.15 CDO76095.1 - 1.8e-29 102.0 0.0 2.3e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CDO76095.1 - 0.0022 18.2 2.1 0.065 13.4 0.0 2.4 2 1 1 3 3 3 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CDO76095.1 - 0.019 14.3 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 CDO76095.1 - 0.052 12.4 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase UAA PF08449.6 CDO76096.1 - 4.7e-63 212.9 11.3 7.3e-63 212.2 7.9 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CDO76096.1 - 1e-10 41.6 14.2 8e-09 35.6 4.5 3.4 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 CDO76096.1 - 0.00016 20.9 6.0 0.081 12.0 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 CDO76096.1 - 0.0002 21.5 21.1 0.00049 20.2 5.2 3.2 3 1 1 4 4 4 2 Multidrug resistance efflux transporter TPT PF03151.11 CDO76096.1 - 0.0014 18.3 15.2 0.0023 17.5 5.3 3.4 2 1 1 3 3 3 1 Triose-phosphate Transporter family GRA6 PF05084.8 CDO76096.1 - 0.16 11.4 0.8 0.72 9.3 0.0 2.0 2 0 0 2 2 2 0 Granule antigen protein (GRA6) UPF0546 PF10639.4 CDO76096.1 - 1.7 8.4 6.6 5.5 6.8 0.5 3.0 2 1 1 3 3 3 0 Uncharacterised protein family UPF0546 GTP_EFTU PF00009.22 CDO76098.1 - 5.4e-54 182.4 0.0 9.5e-54 181.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CDO76098.1 - 3.6e-16 58.7 0.0 8.1e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CDO76098.1 - 1.3e-07 31.4 0.0 3.6e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 CDO76098.1 - 1.2e-05 25.2 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CDO76098.1 - 3.9e-05 23.6 0.0 9.3e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 CDO76098.1 - 0.0088 15.6 0.0 0.12 11.9 0.0 2.7 2 1 0 2 2 2 1 Elongation factor G, domain IV RasGEF PF00617.14 CDO76099.1 - 1e-51 175.3 1.3 1.9e-51 174.4 0.9 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CDO76099.1 - 1.2e-17 63.9 0.1 2.7e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 CDO76099.1 - 5.7e-17 60.8 0.1 1.8e-16 59.2 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CDO76099.1 - 8.5e-15 54.0 0.0 4.8e-13 48.4 0.1 2.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CDO76099.1 - 6.3e-11 41.5 0.0 2.9e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.21 CDO76099.1 - 2.2e-08 33.8 0.2 0.0084 15.9 0.1 2.5 2 0 0 2 2 2 2 WW domain Exo5 PF09810.4 CDO76100.1 - 3.5e-38 131.6 0.0 1.1e-31 110.2 0.0 2.5 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease CwfJ_C_1 PF04677.10 CDO76102.1 - 1e-31 109.0 0.0 1.5e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CDO76102.1 - 5.4e-26 90.9 0.6 3.1e-24 85.3 0.1 2.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 AMP-binding PF00501.23 CDO76103.1 - 3.9e-43 147.4 0.0 5.3e-42 143.6 0.0 1.9 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CDO76103.1 - 2.3e-08 34.8 0.7 5.7e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AhpC-TSA PF00578.16 CDO76104.1 - 5.9e-26 90.5 0.0 1.8e-24 85.7 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CDO76104.1 - 7.5e-16 57.9 0.2 1.9e-15 56.7 0.1 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CDO76104.1 - 0.02 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Med3 PF11593.3 CDO76104.1 - 0.74 8.9 4.5 0.96 8.6 3.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DEC-1_N PF04625.8 CDO76104.1 - 8.8 4.8 8.0 7.8 5.0 4.7 1.4 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region zf-Tim10_DDP PF02953.10 CDO76105.1 - 3.9e-19 67.6 6.0 5.5e-19 67.2 4.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mmp37 PF09139.6 CDO76105.1 - 0.019 14.0 0.0 0.019 14.0 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Phasin_2 PF09361.5 CDO76105.1 - 0.035 14.1 0.4 1.3 9.0 0.0 2.0 1 1 1 2 2 2 0 Phasin protein DUF1178 PF06676.6 CDO76105.1 - 0.036 14.2 0.3 0.063 13.4 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) DAHP_synth_1 PF00793.15 CDO76106.1 - 6.5e-92 307.0 0.0 8e-92 306.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF1183 PF06682.7 CDO76107.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) zf-CCHC PF00098.18 CDO76108.1 - 8.6e-05 22.2 2.3 8.6e-05 22.2 1.6 1.7 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 CDO76108.1 - 0.032 14.2 0.1 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_6 PF15288.1 CDO76108.1 - 0.064 12.9 0.3 0.14 11.8 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDO76108.1 - 0.11 12.1 0.6 0.21 11.2 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_10 PF05971.7 CDO76109.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF890) HNH_2 PF13391.1 CDO76110.1 - 0.00052 19.7 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease LysM PF01476.15 CDO76111.1 - 0.00064 19.5 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 LysM domain DUF3072 PF11272.3 CDO76114.1 - 0.017 14.7 0.2 7.5 6.2 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3072) ECH PF00378.15 CDO76115.1 - 1.9e-76 256.4 0.4 2.6e-76 255.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CDO76115.1 - 0.00015 21.9 0.1 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 CDO76115.1 - 0.0034 17.1 0.9 0.0068 16.1 0.1 1.9 2 1 1 3 3 3 1 Peptidase family S49 Aminotran_1_2 PF00155.16 CDO76116.1 - 1.6e-16 60.1 0.0 2.2e-15 56.4 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II PQ-loop PF04193.9 CDO76118.1 - 1.3e-19 69.5 8.6 4.2e-11 42.2 0.2 3.2 4 0 0 4 4 4 2 PQ loop repeat DUF4191 PF13829.1 CDO76118.1 - 0.27 10.3 1.7 0.64 9.0 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Syndecan PF01034.15 CDO76118.1 - 0.39 10.3 1.5 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Syndecan domain Anp1 PF03452.9 CDO76120.1 - 0.053 12.6 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Anp1 UPF0016 PF01169.14 CDO76120.1 - 1.6 8.8 9.6 2.3 8.4 0.4 3.3 3 1 0 3 3 3 0 Uncharacterized protein family UPF0016 Adap_comp_sub PF00928.16 CDO76121.1 - 1.7e-89 299.4 0.0 2.3e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CDO76121.1 - 5.2e-07 29.4 0.3 9.4e-07 28.6 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1168 PF06658.7 CDO76122.1 - 0.03 13.8 10.0 0.055 12.9 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Transposase_21 PF02992.9 CDO76123.1 - 1.2e-16 60.4 0.0 6.7e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 Daxx PF03344.10 CDO76123.1 - 0.012 14.1 11.8 0.016 13.6 8.2 1.1 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 CDO76123.1 - 0.12 11.4 12.5 0.23 10.5 8.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 CDO76123.1 - 0.12 10.2 16.2 0.18 9.6 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CDO76123.1 - 0.18 9.7 9.4 0.26 9.3 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4218 PF13960.1 CDO76123.1 - 0.2 11.1 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) BUD22 PF09073.5 CDO76123.1 - 4.2 6.3 11.7 6.5 5.7 8.1 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 CDO76123.1 - 8.5 5.5 16.2 13 4.9 11.2 1.1 1 0 0 1 1 1 0 SDA1 Pro-kuma_activ PF09286.6 CDO76124.1 - 2.8e-45 153.8 0.2 7.6e-45 152.4 0.1 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO76124.1 - 4.5e-05 22.7 0.3 7.6e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 Subtilase family DnaJ PF00226.26 CDO76125.1 - 1.2e-18 66.5 0.3 3.9e-18 64.9 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain DNA_pol_A_exo1 PF01612.15 CDO76126.1 - 8.3e-17 61.2 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.1 CDO76126.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FA_desaturase PF00487.19 CDO76127.1 - 1.8e-26 93.1 32.2 3.1e-26 92.3 22.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 CDO76127.1 - 4.6e-05 23.4 0.1 8.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) ABC_tran PF00005.22 CDO76128.1 - 8.5e-28 97.3 0.1 1.4e-27 96.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CDO76128.1 - 7e-10 38.7 11.8 9.5e-10 38.3 8.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CDO76128.1 - 1e-05 24.9 1.4 0.002 17.3 1.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CDO76128.1 - 2.9e-05 23.5 0.2 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CDO76128.1 - 0.00029 20.8 0.1 0.98 9.3 0.0 2.2 1 1 0 2 2 2 2 AAA domain DUF87 PF01935.12 CDO76128.1 - 0.00081 19.2 0.1 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_29 PF13555.1 CDO76128.1 - 0.0017 17.8 0.0 0.0038 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 CDO76128.1 - 0.002 17.8 0.4 0.0055 16.4 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_16 PF13191.1 CDO76128.1 - 0.003 17.5 0.9 0.0051 16.8 0.6 1.4 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CDO76128.1 - 0.0064 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CDO76128.1 - 0.013 15.4 0.3 0.023 14.6 0.2 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 CDO76128.1 - 0.013 14.9 2.0 0.25 10.7 0.1 2.3 1 1 1 2 2 2 0 AAA-like domain MobB PF03205.9 CDO76128.1 - 0.022 14.4 0.1 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CDO76128.1 - 0.049 12.3 0.1 0.08 11.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 CDO76128.1 - 0.068 13.9 0.6 0.15 12.9 0.3 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 CDO76128.1 - 0.081 12.4 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase T2SE PF00437.15 CDO76128.1 - 0.097 11.5 0.1 0.097 11.5 0.1 2.4 3 1 1 4 4 4 0 Type II/IV secretion system protein AAA_18 PF13238.1 CDO76128.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CDO76128.1 - 0.18 11.9 1.9 2.8 8.0 1.3 2.4 1 1 0 1 1 1 0 AAA domain ABC_membrane PF00664.18 CDO76129.1 - 1.2e-15 57.7 12.8 4.1e-15 55.9 6.3 2.7 2 1 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 CDO76129.1 - 1.7e-12 47.8 0.4 4.3e-06 27.0 0.0 2.5 1 1 1 2 2 2 2 ABC transporter AAA_21 PF13304.1 CDO76129.1 - 4.7e-08 33.3 0.0 0.0034 17.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_23 PF13476.1 CDO76129.1 - 7.2e-06 26.4 0.2 2.4e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CDO76129.1 - 1.2e-05 24.6 0.0 0.11 11.6 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CDO76129.1 - 0.001 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 CDO76129.1 - 0.0028 17.1 0.0 0.007 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CDO76129.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CDO76129.1 - 0.025 14.6 0.1 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Med3 PF11593.3 CDO76129.1 - 0.028 13.6 3.7 0.047 12.9 2.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal T2SE PF00437.15 CDO76129.1 - 0.04 12.8 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 CDO76129.1 - 0.056 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 CDO76129.1 - 0.072 13.9 0.7 0.2 12.4 0.5 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CDO76129.1 - 0.14 11.2 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Pro_isomerase PF00160.16 CDO76132.1 - 5.6e-48 163.0 0.2 8e-48 162.5 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CDO76132.1 - 4.3e-08 32.7 8.3 9.3e-07 28.4 0.4 2.5 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 CDO76132.1 - 5.2e-06 25.9 12.8 0.0021 17.8 0.4 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDO76132.1 - 1.2e-05 24.7 5.9 0.0055 16.2 0.4 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 CDO76132.1 - 0.00049 19.9 4.3 0.0058 16.4 0.1 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 CDO76132.1 - 0.0027 17.6 11.6 0.096 12.6 1.4 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CDO76132.1 - 0.026 14.2 3.8 0.96 9.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CDO76132.1 - 0.18 12.4 14.3 1 10.0 1.3 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CDO76132.1 - 0.21 11.9 8.8 4 7.8 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CDO76132.1 - 0.42 11.3 8.3 4.9 8.0 2.5 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDO76132.1 - 0.47 11.0 7.0 29 5.4 0.1 4.0 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CDO76132.1 - 0.72 9.8 4.0 7.5 6.6 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat RhoGAP PF00620.22 CDO76134.1 - 8.8e-11 41.6 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.18 CDO76134.1 - 3.5e-08 33.6 0.0 2.7e-06 27.5 0.0 2.6 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family HABP4_PAI-RBP1 PF04774.10 CDO76135.1 - 3.3e-05 24.3 3.1 4.2e-05 23.9 2.1 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family RNase_H PF00075.19 CDO76137.1 - 3e-14 53.4 0.0 5.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 CDO76137.1 - 2.9e-13 49.6 0.0 4.8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CDO76137.1 - 0.0018 18.5 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase BH3 PF15285.1 CDO76137.1 - 0.086 12.3 0.2 0.3 10.6 0.1 2.0 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting BTB PF00651.26 CDO76139.1 - 0.00017 21.5 0.0 0.00039 20.3 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain CPSF100_C PF13299.1 CDO76140.1 - 0.053 13.7 0.1 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF555 PF04475.7 CDO76141.1 - 0.085 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF555) Sod_Fe_C PF02777.13 CDO76142.1 - 7.7e-35 118.9 0.0 1.2e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CDO76142.1 - 9.4e-32 109.1 3.4 9.4e-32 109.1 2.4 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HET PF06985.6 CDO76143.1 - 1.2e-20 74.0 2.4 5.9e-18 65.3 1.7 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 CDO76144.1 - 5.6e-20 71.9 3.1 3.9e-17 62.7 2.2 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dynamin_M PF01031.15 CDO76145.1 - 3.2e-32 111.5 0.0 1.2e-19 70.2 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 CDO76145.1 - 1.1e-20 74.1 0.0 3.4e-20 72.5 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CDO76145.1 - 0.00014 21.7 0.1 0.0021 17.9 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CDO76145.1 - 0.0021 18.5 0.0 0.0047 17.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GED PF02212.13 CDO76145.1 - 0.0084 15.9 0.1 0.038 13.8 0.0 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_21 PF13304.1 CDO76145.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PHD PF00628.24 CDO76146.1 - 3.8e-08 32.8 11.6 6.1e-08 32.2 8.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CDO76146.1 - 0.009 15.3 7.9 0.016 14.5 5.5 1.4 1 0 0 1 1 1 1 PHD-finger DUF1423 PF07227.6 CDO76146.1 - 0.19 10.3 1.7 0.27 9.8 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) SET PF00856.23 CDO76147.1 - 0.0037 17.5 0.0 0.0037 17.5 0.0 2.7 3 1 0 3 3 3 1 SET domain Ribosomal_S17 PF00366.15 CDO76148.1 - 3.1e-14 52.7 0.3 4.4e-14 52.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Prefoldin_2 PF01920.15 CDO76149.1 - 7.7e-23 80.2 16.1 9.7e-23 79.9 11.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit End3 PF12761.2 CDO76149.1 - 0.0038 16.8 10.0 0.0055 16.3 6.9 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Prefoldin_3 PF13758.1 CDO76149.1 - 0.005 16.5 6.2 0.0068 16.1 4.1 1.3 1 1 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 CDO76149.1 - 0.015 14.8 15.2 0.038 13.5 10.6 1.5 1 1 0 1 1 1 0 IncA protein Prefoldin PF02996.12 CDO76149.1 - 0.027 14.1 3.2 0.027 14.1 2.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF2702 PF10863.3 CDO76149.1 - 0.033 13.9 6.0 0.057 13.1 4.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2702) Occludin_ELL PF07303.8 CDO76149.1 - 0.078 13.7 6.9 0.47 11.2 0.5 2.2 2 0 0 2 2 2 0 Occludin homology domain Macoilin PF09726.4 CDO76149.1 - 0.092 11.0 9.3 0.1 10.8 6.4 1.0 1 0 0 1 1 1 0 Transmembrane protein NPV_P10 PF05531.7 CDO76149.1 - 0.098 12.9 10.3 1.3 9.3 0.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 CDO76149.1 - 0.11 11.8 13.6 0.19 11.0 0.9 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Cluap1 PF10234.4 CDO76149.1 - 0.23 10.6 11.8 0.13 11.4 1.7 2.0 1 1 0 2 2 2 0 Clusterin-associated protein-1 NEP PF10167.4 CDO76149.1 - 0.25 11.0 2.9 0.27 10.9 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein TBPIP PF07106.8 CDO76149.1 - 0.26 10.8 14.1 0.6 9.6 3.7 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4201 PF13870.1 CDO76149.1 - 0.26 10.7 8.7 2.5 7.4 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.2 CDO76149.1 - 0.26 11.1 13.7 0.39 10.5 2.1 2.1 2 0 0 2 2 2 0 Tropomyosin like YgaB PF14182.1 CDO76149.1 - 0.26 11.5 10.9 0.14 12.4 1.6 2.5 2 1 0 2 2 2 0 YgaB-like protein TcdA_TcdB PF12919.2 CDO76149.1 - 0.32 9.4 3.8 0.42 9.0 2.7 1.0 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Leucyl-specific PF14795.1 CDO76149.1 - 0.38 10.6 2.2 5.6 6.8 0.1 2.4 1 1 1 2 2 2 0 Leucine-tRNA synthetase-specific domain ADIP PF11559.3 CDO76149.1 - 0.49 10.2 13.2 0.14 12.0 1.4 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 CDO76149.1 - 0.6 9.8 13.4 2.2 7.9 2.5 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 ERp29 PF07749.7 CDO76149.1 - 0.7 10.5 7.4 3.7 8.2 5.1 2.1 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Ada3 PF10198.4 CDO76149.1 - 0.73 9.5 7.7 2.6 7.8 0.4 2.5 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 APG6 PF04111.7 CDO76149.1 - 0.87 8.5 14.3 24 3.8 10.0 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 CDO76149.1 - 0.91 8.4 7.9 1.1 8.1 5.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 CDO76149.1 - 1.1 9.5 12.6 6 7.2 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DMPK_coil PF08826.5 CDO76149.1 - 1.5 8.7 18.3 0.3 10.9 3.0 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like GAS PF13851.1 CDO76149.1 - 1.6 7.8 15.6 8.5 5.5 10.8 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 CDO76149.1 - 1.7 8.0 15.5 1.5 8.2 2.5 2.0 1 1 0 2 2 2 0 Phage minor structural protein GP20 Spc7 PF08317.6 CDO76149.1 - 1.8 7.1 10.7 2.5 6.6 7.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3166 PF11365.3 CDO76149.1 - 2.4 8.6 10.1 7.2 7.1 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) DUF607 PF04678.8 CDO76149.1 - 2.6 7.9 5.6 9.9 6.0 3.9 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF607 Nup54 PF13874.1 CDO76149.1 - 2.8 7.5 10.2 4.6 6.8 1.1 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.7 CDO76149.1 - 3 7.6 15.0 60 3.3 10.4 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 CDO76149.1 - 4.2 7.3 16.0 1.2 9.1 2.9 2.1 2 0 0 2 2 2 0 FlxA-like protein Syntaxin PF00804.20 CDO76149.1 - 4.8 7.4 9.4 14 5.8 6.6 1.8 1 1 0 1 1 1 0 Syntaxin Seryl_tRNA_N PF02403.17 CDO76149.1 - 5.2 7.1 14.5 7.9e+02 0.1 10.1 2.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PNPase PF03726.9 CDO76149.1 - 7.2 6.9 8.9 1.4 9.2 1.5 2.1 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF641 PF04859.7 CDO76149.1 - 9.4 6.0 11.3 15 5.3 3.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Oxidored_molyb PF00174.14 CDO76150.1 - 2.4e-41 140.9 0.0 4e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CDO76150.1 - 2.4e-26 91.8 0.0 8.2e-26 90.1 0.0 1.8 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 CDO76150.1 - 8.5e-20 70.7 0.0 2.3e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 CDO76150.1 - 9.6e-13 47.7 0.0 2.2e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 CDO76150.1 - 2.2e-11 44.3 0.0 8.7e-09 35.9 0.0 3.2 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain BNR PF02012.15 CDO76150.1 - 0.11 12.4 0.1 0.6 10.1 0.1 2.4 1 0 0 1 1 1 0 BNR/Asp-box repeat V-SNARE PF05008.10 CDO76151.1 - 0.0002 21.4 0.2 0.0013 18.8 0.1 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus DUF883 PF05957.8 CDO76151.1 - 0.44 10.9 4.4 1.7 9.0 3.2 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) PHD PF00628.24 CDO76153.1 - 0.078 12.6 9.5 0.051 13.2 3.2 2.6 2 1 0 2 2 2 0 PHD-finger DUF4206 PF13901.1 CDO76153.1 - 0.096 12.2 3.3 0.19 11.2 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Nop10p PF04135.7 CDO76154.1 - 0.21 11.3 1.6 0.31 10.8 0.1 2.1 2 1 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family rve PF00665.21 CDO76155.1 - 9.7e-11 41.8 0.0 2.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RD3 PF14473.1 CDO76157.1 - 6 6.3 7.0 14 5.1 0.1 2.1 2 0 0 2 2 2 0 RD3 protein Porin_3 PF01459.17 CDO76160.1 - 2.4e-66 223.8 1.8 2.7e-66 223.6 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin MaoC_dehydrat_N PF13452.1 CDO76160.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Rhodanese PF00581.15 CDO76161.1 - 8.2e-08 32.5 0.0 1.1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF3767 PF12597.3 CDO76162.1 - 3.3e-20 71.9 0.0 4.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Thiol-ester_cl PF10569.4 CDO76165.1 - 0.053 12.7 0.1 0.13 11.4 0.1 1.8 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region DUF2668 PF10873.3 CDO76168.1 - 7 6.7 7.7 13 5.9 4.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2668) GST_C PF00043.20 CDO76170.1 - 8.7e-09 35.2 0.0 1.4e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO76170.1 - 5.2e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDO76170.1 - 0.00052 20.4 0.0 0.00075 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CDO76170.1 - 0.00087 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO76170.1 - 0.0036 17.4 0.0 0.007 16.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO76170.1 - 0.016 15.1 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PQQ_3 PF13570.1 CDO76171.1 - 0.081 13.2 0.1 0.31 11.3 0.1 2.0 1 0 0 1 1 1 0 PQQ-like domain NAD_binding_4 PF07993.7 CDO76172.1 - 5.7e-30 104.0 0.0 7.7e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CDO76172.1 - 2e-09 37.2 0.0 9.7e-09 35.0 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CDO76172.1 - 2e-06 27.9 0.0 9e-06 25.8 0.0 2.2 2 1 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 CDO76172.1 - 0.0088 15.9 0.1 0.074 12.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CDO76172.1 - 0.043 12.7 0.0 6.1 5.6 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain AMP-binding PF00501.23 CDO76173.1 - 2.6e-30 105.1 0.0 9.3e-30 103.3 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme RNase_H PF00075.19 CDO76175.1 - 5.4e-20 72.0 0.0 1.2e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 CDO76175.1 - 7.3e-20 71.2 0.0 4.9e-19 68.5 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CDO76175.1 - 0.0002 21.6 1.1 0.0002 21.6 0.8 2.6 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase HTH_Tnp_Tc3_2 PF01498.13 CDO76175.1 - 0.069 13.2 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Transposase Exo_endo_phos PF03372.18 CDO76176.1 - 5.7e-13 49.3 0.1 9.7e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FlxA PF14282.1 CDO76176.1 - 0.0028 17.5 0.5 0.0058 16.5 0.3 1.5 1 0 0 1 1 1 1 FlxA-like protein Rab5-bind PF09311.6 CDO76178.1 - 0.0099 15.7 1.9 0.05 13.5 0.3 2.1 2 0 0 2 2 2 1 Rabaptin-like protein DUF1409 PF07197.7 CDO76178.1 - 0.037 14.1 0.1 0.091 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) HeH PF12949.2 CDO76178.1 - 0.042 13.4 0.0 0.042 13.4 0.0 1.8 2 0 0 2 2 2 0 HeH/LEM domain EthD PF07110.6 CDO76180.1 - 6.5e-12 46.2 0.1 6.5e-12 46.2 0.1 3.3 2 1 0 2 2 2 1 EthD domain BRCT PF00533.21 CDO76180.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain MannoseP_isomer PF01050.13 CDO76180.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Rap1-DNA-bind PF09197.5 CDO76180.1 - 0.019 15.5 11.4 0.18 12.3 1.3 3.4 2 1 1 3 3 3 0 Rap1, DNA-binding Usg PF06233.7 CDO76180.1 - 0.052 13.4 0.4 4.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Usg-like family EthD PF07110.6 CDO76181.1 - 4.9e-14 53.0 0.3 6.5e-14 52.6 0.2 1.2 1 0 0 1 1 1 1 EthD domain PhyH PF05721.8 CDO76182.1 - 1.5e-23 83.9 0.0 2e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HK PF02110.10 CDO76183.1 - 9.8e-73 244.3 1.0 4e-68 229.2 1.5 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 CDO76183.1 - 1.2e-53 180.9 0.2 2.6e-53 179.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 CDO76183.1 - 0.0087 15.2 0.1 0.02 14.0 0.1 1.7 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peptidase_M19 PF01244.16 CDO76183.1 - 0.047 12.6 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) TPMT PF05724.6 CDO76184.1 - 4.4e-34 117.8 0.0 7.2e-34 117.1 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 CDO76184.1 - 1.3e-09 37.8 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO76184.1 - 3.6e-08 33.4 0.1 9.7e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO76184.1 - 4.1e-08 33.6 0.0 5.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO76184.1 - 2.9e-07 31.0 0.0 4.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO76184.1 - 2.6e-06 27.6 0.0 3.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO76184.1 - 2.3e-05 24.7 0.0 3.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO76184.1 - 0.00025 20.7 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CDO76184.1 - 0.0019 17.4 0.0 0.0036 16.5 0.0 1.4 1 1 1 2 2 2 1 Tellurite resistance protein TehB CMAS PF02353.15 CDO76184.1 - 0.0041 16.2 0.0 0.0055 15.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 CDO76184.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SUR7 PF06687.7 CDO76185.1 - 1e-14 54.6 12.3 1.2e-13 51.0 8.6 2.0 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CDO76185.1 - 0.081 12.6 19.4 0.2 11.3 11.7 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PGG PF13962.1 CDO76185.1 - 0.76 9.4 9.9 0.16 11.5 2.5 2.6 2 1 1 3 3 3 0 Domain of unknown function Hid1 PF12722.2 CDO76186.1 - 1.1 6.8 3.5 1.4 6.5 2.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF747 PF05346.6 CDO76187.1 - 9.7e-88 294.3 0.3 9.2e-77 258.3 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic membrane protein family SMC_hinge PF06470.8 CDO76188.1 - 3.9e-28 97.8 0.5 2.9e-27 95.0 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.14 CDO76188.1 - 2.7e-22 79.0 26.7 3.9e-21 75.3 18.5 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Reo_sigmaC PF04582.7 CDO76188.1 - 4.7e-05 22.7 16.7 0.0074 15.5 0.3 5.1 3 2 3 6 6 6 3 Reovirus sigma C capsid protein Barttin PF15462.1 CDO76188.1 - 0.056 13.0 0.1 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) AAA_21 PF13304.1 CDO76188.1 - 0.057 13.3 1.9 0.15 12.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain Baculo_PEP_C PF04513.7 CDO76188.1 - 1.3 8.8 29.6 1 9.1 0.7 6.3 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus RrnaAD PF00398.15 CDO76189.1 - 2.2e-05 23.5 0.1 0.00033 19.7 0.0 2.0 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase WD40 PF00400.27 CDO76190.1 - 1e-19 69.6 14.5 1.7e-08 33.9 0.3 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat DAG1 PF05454.6 CDO76190.1 - 0.033 13.3 0.3 0.057 12.5 0.2 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) PSII_BNR PF14870.1 CDO76190.1 - 0.077 11.9 0.3 0.18 10.7 0.1 1.6 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 Glyco_hydro_61 PF03443.9 CDO76191.1 - 3.6e-63 213.2 0.0 4.2e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TatD_DNase PF01026.16 CDO76192.1 - 1.1e-46 159.1 0.6 1.3e-46 158.9 0.4 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 CDO76192.1 - 1.1e-06 28.4 0.5 4.1e-06 26.5 0.3 2.2 1 1 0 1 1 1 1 Amidohydrolase ALAD PF00490.16 CDO76193.1 - 8.2e-123 409.4 0.0 1e-122 409.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CPSF73-100_C PF11718.3 CDO76194.1 - 2.2e-55 187.3 0.0 3.4e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CDO76194.1 - 7.8e-31 106.6 0.0 2.7e-30 104.9 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 CDO76194.1 - 1.2e-12 47.8 0.5 4.8e-12 45.9 0.3 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 CDO76194.1 - 1.1e-11 44.3 0.2 2.4e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CDO76194.1 - 2.5e-09 36.9 0.9 5.5e-09 35.8 0.6 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CDO76194.1 - 3.6e-06 26.7 0.1 1.5e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF2264 PF10022.4 CDO76195.1 - 6.6e-130 432.9 0.1 8.1e-130 432.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DUF1638 PF07796.6 CDO76195.1 - 0.084 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) Transposase_21 PF02992.9 CDO76200.1 - 2.9e-15 55.9 0.0 1.4e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 CDO76200.1 - 0.00049 19.5 0.3 0.0012 18.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) SGL PF08450.7 CDO76202.1 - 1.1e-24 87.1 0.0 1.9e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CDO76202.1 - 3.2e-06 27.0 0.0 1.1e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 CDO76202.1 - 0.00023 21.0 0.0 0.0006 19.7 0.0 1.7 1 0 0 1 1 1 1 Arylesterase F-box-like PF12937.2 CDO76203.1 - 1.1e-05 25.0 0.0 3.7e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 F-box-like Hydrolase PF00702.21 CDO76204.1 - 2.7e-14 54.1 1.2 2.5e-10 41.1 0.7 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDO76204.1 - 9.5e-13 48.7 0.0 7.9e-12 45.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CDO76204.1 - 1.5e-12 47.0 0.0 1.5e-12 47.0 0.0 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CDO76204.1 - 4.3e-12 45.8 0.0 9.3e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CDO76204.1 - 0.0017 18.0 0.1 0.039 13.5 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CDO76204.1 - 0.046 13.9 0.0 0.19 11.9 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase VSG_B PF13206.1 CDO76204.1 - 0.27 10.3 0.1 0.42 9.6 0.1 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain Asp PF00026.18 CDO76205.1 - 3.6e-20 72.4 0.0 2.3e-10 40.2 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO76205.1 - 0.0012 18.7 0.3 0.0047 16.9 0.2 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Fungal_trans PF04082.13 CDO76206.1 - 1.1e-24 86.7 0.0 1.8e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4175 PF13779.1 CDO76206.1 - 2.1 5.9 8.8 3.3 5.3 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mito_carr PF00153.22 CDO76207.1 - 1.6e-58 194.4 0.9 1e-18 66.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ferric_reduct PF01794.14 CDO76208.1 - 3.3e-16 59.5 7.3 9.7e-16 58.0 5.0 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CDO76208.1 - 4.1e-16 58.7 0.0 1.6e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 CDO76208.1 - 5.2e-16 58.9 0.0 9.4e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain CaATP_NAI PF12515.3 CDO76208.1 - 0.022 14.2 0.5 0.055 12.9 0.3 1.6 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain NAD_binding_6 PF08030.7 CDO76209.1 - 6.6e-21 74.8 0.0 1.2e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CDO76209.1 - 9.4e-17 60.8 0.0 2.4e-15 56.3 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 CDO76209.1 - 0.0019 18.3 3.7 0.0047 16.9 2.6 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Pyr_redox_2 PF07992.9 CDO76210.1 - 8.1e-27 94.4 0.0 1.2e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO76210.1 - 1e-11 45.0 0.0 1.9e-09 37.7 0.0 3.5 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDO76210.1 - 6.7e-05 23.0 0.1 0.065 13.2 0.0 3.7 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO76210.1 - 0.099 11.0 0.4 0.39 9.1 0.0 2.0 1 1 1 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 CDO76210.1 - 0.16 12.2 0.1 2.1 8.6 0.0 2.6 3 0 0 3 3 3 0 Putative NAD(P)-binding RVT_2 PF07727.9 CDO76211.1 - 2.1e-89 298.7 0.1 3.5e-89 298.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO76211.1 - 3.7e-28 98.0 0.0 8.6e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDO76211.1 - 1.2e-05 24.7 0.1 3e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Mem_trans PF03547.13 CDO76212.1 - 4.8e-14 51.4 0.0 6.6e-10 37.8 0.0 2.2 2 0 0 2 2 2 2 Membrane transport protein RVT_1 PF00078.22 CDO76213.1 - 0.021 14.1 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Trs65 PF12735.2 CDO76214.1 - 8.3e-12 45.0 0.0 8.3e-12 45.0 0.0 2.4 3 1 0 3 3 3 1 TRAPP trafficking subunit Trs65 DUF2360 PF10152.4 CDO76215.1 - 3.3 7.9 7.4 40 4.4 0.0 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) MULE PF10551.4 CDO76217.1 - 2.2e-07 30.9 0.0 6.1e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 CDO76217.1 - 0.031 13.7 0.2 0.067 12.6 0.1 1.5 1 0 0 1 1 1 0 SWIM zinc finger Snf7 PF03357.16 CDO76217.1 - 0.063 12.6 0.3 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 Snf7 HET PF06985.6 CDO76218.1 - 2.4e-18 66.6 1.3 5.6e-15 55.7 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PTCB-BRCT PF12738.2 CDO76219.1 - 8.5e-26 89.5 3.0 1.8e-16 59.7 0.2 5.5 6 0 0 6 6 6 3 twin BRCT domain BRCT PF00533.21 CDO76219.1 - 2.7e-21 75.5 0.0 4.4e-07 29.9 0.0 5.2 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 CDO76220.1 - 1.3e-70 237.4 0.0 1.8e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76220.1 - 3.9e-38 131.0 0.0 6.9e-38 130.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CDO76220.1 - 5.4e-17 61.6 0.1 9.5e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 CDO76220.1 - 7e-06 25.2 0.0 1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO76220.1 - 1.7e-05 24.6 0.0 0.0024 17.6 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CDO76220.1 - 4.9e-05 22.4 0.0 0.0001 21.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CDO76221.1 - 3e-41 141.3 0.0 1.7e-28 99.4 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76221.1 - 5.8e-16 58.3 0.0 3e-10 39.6 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 CDO76221.1 - 3.5e-14 52.6 0.0 6.9e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain APH PF01636.18 CDO76221.1 - 0.067 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 CDO76222.1 - 4.8e-59 199.6 0.0 6.2e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76222.1 - 6.1e-35 120.5 0.0 1.7e-34 119.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CDO76222.1 - 5.7e-12 45.5 0.5 1.3e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 FHA domain APH PF01636.18 CDO76222.1 - 2.3e-06 27.5 0.9 3.3e-05 23.7 0.6 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CDO76222.1 - 3.4e-05 22.9 0.3 5.6e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CDO76222.1 - 0.0019 17.6 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 CDO76222.1 - 0.045 12.6 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4228 PF14009.1 CDO76223.1 - 0.19 11.8 5.7 0.28 11.2 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) GlyL_C PF12524.3 CDO76223.1 - 0.28 11.1 8.1 0.13 12.1 0.9 2.4 2 0 0 2 2 2 0 dsDNA virus glycoprotein L C terminal Glyoxalase PF00903.20 CDO76225.1 - 2.1e-22 79.4 0.0 3.7e-22 78.6 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CDO76225.1 - 1e-14 55.0 0.0 2.4e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CDO76225.1 - 8.5e-07 28.9 0.0 2.2e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CDO76225.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.6 2 0 0 2 2 2 0 Glyoxalase-like domain MRI PF15325.1 CDO76226.1 - 0.15 13.0 0.3 0.27 12.1 0.2 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF4246 PF14033.1 CDO76227.1 - 1.4e-40 139.4 0.0 3.6e-37 128.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) PLDc PF00614.17 CDO76228.1 - 2.1e-15 55.9 8.2 6.3e-09 35.3 0.2 2.7 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CDO76228.1 - 7.4e-14 51.5 0.1 2.5e-07 30.5 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain Prenyltrans_2 PF13249.1 CDO76229.1 - 8.9e-10 38.9 0.0 1.7e-05 25.1 0.0 1.8 1 1 1 2 2 2 2 Prenyltransferase-like Prenyltrans PF00432.16 CDO76229.1 - 4.4e-08 32.5 0.0 4.4e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 CDO76229.1 - 0.023 14.7 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Prenyltransferase-like Prenyltrans PF00432.16 CDO76230.1 - 1.8e-06 27.4 5.8 7.5e-05 22.2 0.1 2.6 2 1 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat Tox-GHH PF15636.1 CDO76230.1 - 0.0002 20.8 0.9 0.0017 17.9 0.6 2.2 1 1 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin F-box-like PF12937.2 CDO76231.1 - 9e-12 44.5 0.9 9e-12 44.5 0.6 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 CDO76231.1 - 0.00022 20.7 0.6 0.0008 19.0 0.4 1.9 1 0 0 1 1 1 1 F-box domain p450 PF00067.17 CDO76234.1 - 2.9e-62 210.7 0.0 1e-47 162.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 RVT_2 PF07727.9 CDO76235.1 - 2.5e-78 262.4 0.0 3.6e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO76235.1 - 3.3e-22 78.8 0.1 3.1e-21 75.6 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain UBN2 PF14223.1 CDO76235.1 - 1e-13 51.0 0.0 1.8e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CDO76235.1 - 1.3e-11 44.0 0.0 3.1e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO76235.1 - 0.00013 21.5 0.0 0.00032 20.2 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 CDO76235.1 - 0.019 14.8 6.2 0.02 14.8 3.2 1.9 2 0 0 2 2 2 0 Zinc knuckle Leo1 PF04004.8 CDO76236.1 - 0.013 15.1 0.2 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Leo1-like protein Sugar_tr PF00083.19 CDO76237.1 - 1.3e-33 116.3 25.0 2e-33 115.6 17.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO76237.1 - 2.2e-31 108.8 33.3 2.2e-31 108.8 23.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.14 CDO76237.1 - 0.0011 17.6 11.4 0.0017 16.9 7.9 1.3 1 0 0 1 1 1 1 LacY proton/sugar symporter MtrF PF09472.5 CDO76237.1 - 1.6 7.9 5.0 1.7 7.9 0.4 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) GNAT_acetyltr_2 PF13718.1 CDO76238.1 - 2.7e-76 255.2 0.0 4.9e-76 254.4 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CDO76238.1 - 1.2e-64 217.2 1.3 2e-64 216.4 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 CDO76238.1 - 1.9e-38 130.0 0.1 4.2e-38 128.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CDO76238.1 - 1.6e-33 114.7 0.2 4.6e-33 113.3 0.1 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 CDO76238.1 - 0.00092 19.3 0.0 0.017 15.2 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO76238.1 - 0.063 13.3 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family zf-FCS PF06467.9 CDO76239.1 - 0.051 13.2 2.0 0.093 12.3 1.4 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif NinG PF05766.7 CDO76239.1 - 0.15 11.7 0.3 0.26 10.9 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein GTP_CH_N PF12471.3 CDO76240.1 - 1.9e-90 301.7 0.0 2.9e-90 301.1 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 CDO76240.1 - 1.1e-10 41.0 0.0 3.6e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 GTP cyclohydrolase II Ribonuclease_3 PF00636.21 CDO76241.1 - 4.4e-40 136.6 0.0 3.9e-20 72.4 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CDO76241.1 - 8.5e-22 77.4 0.1 4.1e-07 30.0 0.0 4.6 4 0 0 4 4 4 4 Ribonuclease-III-like DEAD PF00270.24 CDO76241.1 - 6.1e-19 68.1 0.0 3.4e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 CDO76241.1 - 1.4e-13 50.4 0.0 3.4e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 CDO76241.1 - 2e-13 49.9 0.0 4.9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO76241.1 - 3.5e-11 43.2 0.0 7.1e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 CDO76241.1 - 0.091 12.1 0.0 0.25 10.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Ion_trans_2 PF07885.11 CDO76242.1 - 3.9e-11 42.4 2.9 3.9e-11 42.4 2.0 2.3 1 1 1 2 2 2 1 Ion channel Ion_trans PF00520.26 CDO76242.1 - 0.0016 17.6 9.3 0.032 13.4 0.1 2.5 2 1 1 3 3 3 2 Ion transport protein Lig_chan PF00060.21 CDO76242.1 - 0.0069 16.1 0.1 0.016 14.8 0.1 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel OAR PF03826.12 CDO76242.1 - 0.88 9.1 3.8 0.26 10.8 0.2 1.9 2 0 0 2 2 2 0 OAR domain RVT_1 PF00078.22 CDO76243.1 - 3.9e-28 98.2 0.0 6.1e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO76243.1 - 8.1e-13 48.8 0.0 2.2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO76243.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DAO PF01266.19 CDO76244.1 - 2.3e-47 161.6 0.0 2.9e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 CDO76244.1 - 2e-07 29.6 0.0 0.012 13.7 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 CDO76244.1 - 5.2e-05 23.1 0.1 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CDO76244.1 - 0.0031 17.8 0.1 0.023 15.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CDO76244.1 - 0.0033 16.3 0.0 0.44 9.3 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CDO76244.1 - 0.0074 16.3 0.0 0.088 12.8 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO76244.1 - 0.07 12.9 0.1 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CDO76244.1 - 0.085 12.7 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CDO76244.1 - 0.13 11.2 0.2 2.1 7.3 0.0 2.3 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NDUFA12 PF05071.11 CDO76245.1 - 2.2e-27 95.5 5.9 3.2e-27 95.0 4.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Abhydrolase_6 PF12697.2 CDO76246.1 - 1.3e-26 93.8 0.2 1.8e-26 93.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO76246.1 - 6.1e-14 52.1 0.0 7.9e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO76246.1 - 2.3e-10 40.3 0.0 1.1e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CDO76246.1 - 0.00071 19.0 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.15 CDO76246.1 - 0.014 15.6 0.0 0.024 14.8 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.3 CDO76246.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase His_biosynth PF00977.16 CDO76247.1 - 5.2e-33 114.2 0.0 6.6e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Fe-ADH PF00465.14 CDO76248.1 - 4.2e-87 292.1 0.0 5.2e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CDO76248.1 - 9.3e-11 41.5 0.0 1.3e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase ATP-synt_C PF00137.16 CDO76248.1 - 0.17 11.8 1.1 0.45 10.4 0.8 1.7 1 0 0 1 1 1 0 ATP synthase subunit C Asp PF00026.18 CDO76249.1 - 6.9e-28 97.8 0.4 7e-27 94.4 0.3 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO76249.1 - 3.8e-05 23.6 0.6 0.00093 19.1 0.1 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO76249.1 - 0.00093 19.6 0.2 0.26 11.8 0.1 2.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO76249.1 - 0.0046 16.7 0.1 0.17 11.7 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 CDO76249.1 - 0.034 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal PPR_2 PF13041.1 CDO76250.1 - 9.7e-20 70.2 0.0 1.1e-10 41.3 0.0 5.2 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.1 CDO76250.1 - 1.7e-10 40.3 6.2 0.011 15.9 0.0 7.0 6 1 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 CDO76250.1 - 2.6e-09 36.4 0.0 0.0034 17.2 0.0 5.5 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.2 CDO76250.1 - 2e-06 27.1 0.1 0.42 10.1 0.0 4.5 4 0 0 4 4 4 2 PPR repeat TPR_19 PF14559.1 CDO76250.1 - 7.3e-06 26.2 0.1 0.0049 17.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO76250.1 - 0.00081 19.8 2.6 0.24 12.1 0.1 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Proteasom_PSMB PF10508.4 CDO76250.1 - 0.14 10.3 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Mur_ligase_M PF08245.7 CDO76251.1 - 8.9e-07 29.1 0.4 0.00033 20.7 0.1 3.3 2 1 0 2 2 2 1 Mur ligase middle domain Sulfotransfer_3 PF13469.1 CDO76251.1 - 0.037 14.9 0.0 0.091 13.6 0.0 1.7 1 0 0 1 1 1 0 Sulfotransferase family Slx4 PF09494.5 CDO76252.1 - 3.7e-07 29.7 0.0 6.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease IBN_N PF03810.14 CDO76254.1 - 6.1e-14 51.6 0.0 5.8e-10 38.9 0.0 3.1 2 0 0 2 2 2 2 Importin-beta N-terminal domain HEAT_2 PF13646.1 CDO76254.1 - 9.6e-05 22.5 4.4 0.00073 19.7 0.2 3.8 4 0 0 4 4 4 1 HEAT repeats Xpo1 PF08389.7 CDO76254.1 - 0.0018 18.1 0.3 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein CDC27 PF09507.5 CDO76255.1 - 5.5e-07 29.1 86.2 8.3e-05 21.9 59.7 2.7 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 POPLD PF08170.7 CDO76255.1 - 7.5 6.4 5.9 0.75 9.6 0.5 2.0 2 0 0 2 2 2 0 POPLD (NUC188) domain Pex2_Pex12 PF04757.9 CDO76256.1 - 2.5e-23 82.7 7.8 1.9e-15 56.8 3.5 2.2 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.1 CDO76256.1 - 1.8e-05 24.3 1.9 3.9e-05 23.2 0.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CDO76256.1 - 0.00024 20.8 1.7 0.0046 16.7 0.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CDO76256.1 - 0.00051 19.6 2.2 0.0034 17.0 1.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO76256.1 - 0.0046 16.9 2.3 0.0046 16.9 1.6 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDO76256.1 - 0.0068 16.2 1.5 0.023 14.5 1.0 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CDO76256.1 - 0.008 15.8 0.1 0.05 13.3 0.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CDO76256.1 - 0.024 14.3 2.3 0.17 11.5 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDO76256.1 - 0.03 14.4 0.8 0.16 12.0 0.5 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger RDD PF06271.7 CDO76256.1 - 0.37 10.6 1.8 1.8 8.4 1.1 2.0 1 1 0 1 1 1 0 RDD family tRNA-synt_2d PF01409.15 CDO76257.1 - 1.1e-84 283.5 0.0 1.6e-55 188.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 CDO76257.1 - 6.7e-05 21.8 0.5 0.0024 16.7 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 CDO76257.1 - 8e-05 22.2 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1212 PF06738.7 CDO76258.1 - 2e-32 112.2 4.6 2e-32 112.2 3.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CDO76258.1 - 6.7e-12 45.4 13.9 6.7e-12 45.4 9.7 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) Acetyltransf_1 PF00583.19 CDO76259.1 - 3.6e-13 49.3 0.6 1.5e-12 47.3 0.4 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDO76259.1 - 3.5e-09 36.7 0.2 4.8e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CDO76259.1 - 4.2e-08 33.4 0.0 1.2e-07 31.9 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDO76259.1 - 9.3e-08 32.2 0.0 2.6e-07 30.7 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO76259.1 - 5e-07 29.3 0.0 1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 CDO76259.1 - 3.5e-05 23.8 0.0 6.1e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CDO76259.1 - 4.1e-05 23.5 0.1 8.1e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CDO76259.1 - 0.029 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 CDO76259.1 - 0.083 12.7 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2370 PF10176.4 CDO76262.1 - 8e-71 238.0 0.0 1.8e-70 236.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Pkinase PF00069.20 CDO76263.1 - 5.1e-10 38.9 0.0 4.3e-08 32.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76263.1 - 0.0034 16.4 0.0 0.006 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-met PF12874.2 CDO76264.1 - 7.8e-20 70.3 28.6 0.0018 18.4 0.4 7.8 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CDO76264.1 - 8.5e-20 69.8 40.1 0.0093 16.2 0.4 8.6 8 1 1 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CDO76264.1 - 4.7e-18 64.7 31.7 3.9e-06 26.8 0.4 7.4 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CDO76264.1 - 5.4e-14 51.4 44.5 0.047 14.0 0.1 8.7 8 1 1 9 9 9 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CDO76264.1 - 9.9e-07 28.4 43.3 0.011 15.6 1.3 8.7 8 1 1 9 9 9 5 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CDO76264.1 - 1.2e-06 28.5 26.6 0.0028 17.7 6.5 4.3 2 2 2 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.6 CDO76264.1 - 0.15 11.7 0.1 0.15 11.7 0.1 4.5 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.1 CDO76264.1 - 1.1 9.6 0.0 1.1 9.6 0.0 7.9 9 0 0 9 9 9 0 Zinc-finger double domain Cactin_mid PF10312.4 CDO76265.1 - 1.4e-62 210.4 5.8 4.2e-62 208.8 4.0 1.9 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 CDO76265.1 - 1.3e-56 189.5 3.6 2.9e-56 188.4 2.5 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein B3_4 PF03483.12 CDO76265.1 - 1e-28 99.9 0.1 2.5e-28 98.7 0.0 1.7 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CDO76265.1 - 1.5e-18 66.3 0.0 3e-13 49.3 0.0 3.3 3 0 0 3 3 3 2 tRNA synthetase B5 domain AAA_2 PF07724.9 CDO76266.1 - 2.2e-31 109.0 0.0 4e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CDO76266.1 - 6.8e-12 45.7 0.0 1.4e-11 44.7 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CDO76266.1 - 3.1e-07 30.1 0.0 7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_17 PF13207.1 CDO76266.1 - 1.1e-05 26.1 0.0 2.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CDO76266.1 - 9.6e-05 22.1 0.3 0.0019 17.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CDO76266.1 - 0.0001 21.5 0.0 0.00049 19.3 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CDO76266.1 - 0.00013 22.0 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 CDO76266.1 - 0.00015 21.8 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CDO76266.1 - 0.00022 21.3 0.4 0.0031 17.6 0.1 2.4 2 1 1 3 3 2 1 AAA domain T2SE PF00437.15 CDO76266.1 - 0.00088 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 CDO76266.1 - 0.0012 18.2 0.0 0.0056 16.1 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 CDO76266.1 - 0.0018 17.7 0.0 0.055 12.9 0.0 2.3 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 CDO76266.1 - 0.0022 17.8 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CDO76266.1 - 0.0025 17.7 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CDO76266.1 - 0.0028 17.2 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CDO76266.1 - 0.004 17.2 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.7 CDO76266.1 - 0.0055 15.7 0.0 0.0095 15.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CDO76266.1 - 0.0098 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO76266.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DEAD PF00270.24 CDO76266.1 - 0.014 14.8 0.1 0.065 12.7 0.1 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.22 CDO76266.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.11 CDO76266.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 CDO76266.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 CDO76266.1 - 0.032 13.6 0.1 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain UPF0079 PF02367.12 CDO76266.1 - 0.049 13.2 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 CDO76266.1 - 0.086 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 CDO76266.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CDO76266.1 - 0.13 11.7 0.0 0.13 11.7 0.0 2.3 3 0 0 3 3 2 0 P-loop containing region of AAA domain SKI PF01202.17 CDO76266.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase MobB PF03205.9 CDO76266.1 - 0.16 11.7 0.2 0.26 10.9 0.2 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TIP49 PF06068.8 CDO76266.1 - 0.16 10.6 0.0 0.25 9.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus ResIII PF04851.10 CDO76266.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ran_BP1 PF00638.13 CDO76267.1 - 9.3e-51 171.0 0.6 2.3e-50 169.7 0.4 1.6 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 CDO76267.1 - 2.7e-06 27.0 2.7 3e-06 26.8 0.8 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1681) WH1 PF00568.18 CDO76267.1 - 3.6e-05 23.4 0.8 0.00026 20.6 0.6 2.0 1 1 0 1 1 1 1 WH1 domain HAUS6_N PF14661.1 CDO76267.1 - 0.16 11.2 10.2 0.29 10.4 7.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus EBV-NA3 PF05009.7 CDO76267.1 - 0.18 11.0 7.2 0.29 10.3 5.0 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DDHD PF02862.12 CDO76267.1 - 1.2 8.9 10.0 1.8 8.3 7.0 1.3 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 CDO76267.1 - 4.2 7.2 11.3 5 7.0 7.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family EMP24_GP25L PF01105.19 CDO76268.1 - 4.2e-49 166.7 0.1 4.7e-49 166.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kinesin PF00225.18 CDO76269.1 - 2.3e-106 355.2 0.0 3.6e-106 354.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Amidohydro_2 PF04909.9 CDO76270.1 - 3.6e-10 39.8 0.1 5.1e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase LON PF02190.11 CDO76271.1 - 1.4e-20 73.9 0.0 7.9e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 CDO76271.1 - 2e-09 37.1 20.9 0.00012 21.8 7.4 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CDO76271.1 - 2.1e-09 36.9 16.3 4.6e-06 26.2 6.7 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 CDO76271.1 - 2e-08 33.7 19.5 1.9e-07 30.5 7.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO76271.1 - 3.1e-08 33.2 23.8 2.3e-07 30.4 8.5 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 CDO76271.1 - 3.8e-08 33.2 22.0 3.9e-07 29.9 7.5 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO76271.1 - 1.2e-07 31.2 5.6 1.2e-07 31.2 3.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CDO76271.1 - 0.0042 16.8 6.9 0.16 11.7 1.8 2.7 3 0 0 3 3 3 2 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CDO76271.1 - 0.0088 15.7 12.5 0.28 10.9 3.1 2.7 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_4 PF14570.1 CDO76271.1 - 0.068 12.7 7.5 0.026 14.0 2.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CDO76271.1 - 0.37 10.9 11.6 0.029 14.4 3.6 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger F-box-like PF12937.2 CDO76272.1 - 1.2e-05 24.9 0.6 1.2e-05 24.9 0.4 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDO76272.1 - 0.2 11.3 0.1 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 F-box domain G6PD_C PF02781.11 CDO76273.1 - 9.7e-85 283.9 0.0 3e-48 164.1 0.0 2.1 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CDO76273.1 - 1e-54 185.5 0.0 3.1e-54 183.9 0.0 1.7 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 CDO76273.1 - 0.053 14.0 0.0 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold FimP PF09766.4 CDO76274.1 - 1.5e-29 103.2 8.8 1.6e-29 103.0 6.1 1.0 1 0 0 1 1 1 1 Fms-interacting protein Paf67 PF10255.4 CDO76274.1 - 0.0067 15.3 1.4 0.008 15.1 1.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 DUF1204 PF06721.6 CDO76274.1 - 0.055 12.7 3.0 0.06 12.5 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) HAUS-augmin3 PF14932.1 CDO76274.1 - 0.12 11.5 9.5 0.15 11.1 6.6 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2681 PF10883.3 CDO76274.1 - 0.47 10.6 4.2 0.24 11.6 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF342 PF03961.8 CDO76274.1 - 0.67 8.3 5.2 0.81 8.0 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UQ_con PF00179.21 CDO76275.1 - 1.3e-33 115.3 0.1 5e-27 94.0 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme MARVEL PF01284.18 CDO76276.1 - 0.25 11.1 9.0 0.57 10.0 6.2 1.6 1 1 0 1 1 1 0 Membrane-associating domain MARVEL PF01284.18 CDO76277.1 - 0.025 14.4 10.5 0.042 13.6 7.1 1.4 1 1 0 1 1 1 0 Membrane-associating domain DUF4131 PF13567.1 CDO76277.1 - 0.06 12.7 5.8 5.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3820 PF12843.2 CDO76277.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3820) AMP-binding PF00501.23 CDO76278.1 - 5.5e-36 123.8 0.0 2e-35 122.0 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.20 CDO76281.1 - 2e-12 46.8 0.0 1.5e-09 37.4 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76281.1 - 4.2e-05 22.7 0.0 8.3e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase rve PF00665.21 CDO76282.1 - 9.8e-21 74.0 0.0 1.8e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO76282.1 - 1.6e-07 30.9 0.1 3e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SPX PF03105.14 CDO76283.1 - 0.71 9.6 9.4 1.9 8.1 1.1 2.1 2 0 0 2 2 2 0 SPX domain FlxA PF14282.1 CDO76283.1 - 1.4 8.8 6.2 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 FlxA-like protein Ycf1 PF05758.7 CDO76283.1 - 1.6 6.3 3.6 1.7 6.2 2.5 1.1 1 0 0 1 1 1 0 Ycf1 UBN_AB PF14075.1 CDO76284.1 - 0.00064 19.4 5.5 0.076 12.6 0.0 2.3 2 0 0 2 2 2 2 Ubinuclein conserved middle domain SAPS PF04499.10 CDO76284.1 - 0.79 8.2 3.6 0.86 8.1 2.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TSA PF03249.8 CDO76284.1 - 0.95 7.9 4.5 1.6 7.1 3.1 1.4 1 0 0 1 1 1 0 Type specific antigen DUF2390 PF09523.5 CDO76284.1 - 2.7 8.1 11.3 13 6.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) rve PF00665.21 CDO76285.1 - 4.7e-20 71.8 0.0 8.8e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO76285.1 - 7.6e-08 31.9 0.0 1.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ferrochelatase PF00762.14 CDO76285.1 - 0.023 13.6 0.5 3.3 6.5 0.1 2.3 1 1 1 2 2 2 0 Ferrochelatase SAICAR_synt PF01259.13 CDO76286.1 - 1.1e-87 293.2 0.0 1.5e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase MFS_1 PF07690.11 CDO76287.1 - 1.2e-28 99.9 35.4 1.2e-28 99.9 24.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Hormone_3 PF00159.13 CDO76287.1 - 0.14 12.1 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Pancreatic hormone peptide Dimer_Tnp_hAT PF05699.9 CDO76288.1 - 2.7e-12 46.1 0.2 2.6e-11 42.9 0.1 2.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 CDO76288.1 - 0.026 14.4 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Peptidase_S64 PF08192.6 CDO76288.1 - 0.58 8.4 1.6 0.84 7.8 1.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 DNA_pol_B PF00136.16 CDO76289.1 - 4.4e-115 385.1 0.1 6e-115 384.6 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 CDO76289.1 - 5.4e-57 192.1 0.9 9.2e-57 191.4 0.6 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 CDO76289.1 - 6.2e-25 87.7 0.0 2.1e-24 86.0 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 CDO76289.1 - 5.1e-17 61.4 6.9 5.1e-17 61.4 4.8 2.1 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Glutaredoxin PF00462.19 CDO76290.1 - 5.2e-18 64.7 0.0 1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin ArsC PF03960.10 CDO76290.1 - 0.087 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 ArsC family DDE_3 PF13358.1 CDO76291.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO76291.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain AICARFT_IMPCHas PF01808.13 CDO76292.1 - 2.1e-97 325.9 0.1 2.9e-97 325.5 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CDO76292.1 - 2.4e-24 85.1 0.0 4.3e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain FAD_binding_3 PF01494.14 CDO76293.1 - 2.6e-20 72.8 0.6 8.1e-20 71.1 0.4 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CDO76293.1 - 2.6e-11 43.0 5.0 2.6e-06 26.5 1.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDO76293.1 - 3e-06 27.1 2.1 6.9e-06 26.0 1.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 CDO76293.1 - 1.3e-05 24.0 0.1 0.018 13.6 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 CDO76293.1 - 2e-05 23.2 0.2 9.7e-05 20.9 0.1 1.8 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 CDO76293.1 - 7.2e-05 21.8 1.0 7.2e-05 21.8 0.7 2.0 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 CDO76293.1 - 0.00011 22.2 0.8 0.00029 20.9 0.2 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CDO76293.1 - 0.00012 21.3 0.5 0.11 11.4 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 CDO76293.1 - 0.00015 22.0 0.1 0.0014 18.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDO76293.1 - 0.00016 21.6 0.0 0.00074 19.4 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDO76293.1 - 0.00031 19.8 0.1 0.00067 18.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 CDO76293.1 - 0.00045 19.4 0.1 0.00079 18.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CDO76293.1 - 0.0058 15.5 1.0 0.79 8.5 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 CDO76293.1 - 0.022 14.5 1.6 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 CDO76293.1 - 0.024 13.5 0.1 0.04 12.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 CDO76293.1 - 0.037 13.7 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 CDO76293.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CDO76293.1 - 0.077 12.5 0.2 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gag_p12 PF01141.13 CDO76294.1 - 0.042 13.9 9.5 2.7 8.2 4.5 2.7 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 RabGAP-TBC PF00566.13 CDO76295.1 - 8.1e-46 156.1 0.0 1.5e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 CDO76295.1 - 3.8e-06 26.3 2.2 0.0012 18.5 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CDO76295.1 - 2.6e-05 23.7 0.6 0.018 14.6 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 CDO76295.1 - 2.8e-05 24.1 0.8 0.003 17.6 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CDO76295.1 - 0.0001 21.3 0.2 0.00095 18.3 0.0 2.5 2 0 0 2 2 2 1 EF hand GRAM PF02893.15 CDO76295.1 - 0.0017 17.8 0.0 0.0052 16.2 0.0 1.8 1 0 0 1 1 1 1 GRAM domain SPARC_Ca_bdg PF10591.4 CDO76295.1 - 0.092 12.7 0.1 0.32 11.0 0.1 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region WD40 PF00400.27 CDO76296.1 - 4.5e-67 219.7 23.8 8e-13 47.7 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CDO76296.1 - 5.6e-09 35.9 0.8 0.0017 18.0 0.0 3.9 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CDO76296.1 - 1.8e-05 23.0 10.8 0.19 9.8 0.8 4.7 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Pectate_lyase22 PF14583.1 CDO76296.1 - 0.013 13.9 0.1 0.072 11.5 0.0 2.1 1 1 1 3 3 3 0 Oligogalacturonate lyase DUF1513 PF07433.6 CDO76296.1 - 0.017 14.0 0.6 5.9 5.6 0.0 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1513) Mito_fiss_reg PF05308.6 CDO76296.1 - 0.036 13.4 1.5 0.053 12.8 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CDtoxinA PF03498.9 CDO76296.1 - 0.044 13.1 3.3 1.6 8.1 0.4 2.4 1 1 0 2 2 2 0 Cytolethal distending toxin A/C family Aldo_ket_red PF00248.16 CDO76297.1 - 1.3e-39 135.7 0.1 8.8e-34 116.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family p450 PF00067.17 CDO76298.1 - 9.5e-55 185.9 0.0 2.2e-54 184.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF1771 PF08590.5 CDO76298.1 - 0.11 12.4 0.2 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Abhydrolase_3 PF07859.8 CDO76299.1 - 1.4e-27 96.6 0.0 1.9e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CDO76299.1 - 9.9e-14 50.7 0.0 1.4e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 CDO76299.1 - 0.0013 17.5 0.2 0.005 15.6 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CDO76299.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CDO76299.1 - 0.037 13.2 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.3 CDO76299.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HD_3 PF13023.1 CDO76300.1 - 6.3e-22 78.0 1.9 4.2e-12 46.1 0.0 2.1 1 1 1 2 2 2 2 HD domain HD PF01966.17 CDO76300.1 - 3.8e-05 23.6 0.3 0.0001 22.2 0.2 1.6 1 1 0 1 1 1 1 HD domain RINGv PF12906.2 CDO76301.1 - 1.2e-15 57.3 8.3 2e-15 56.5 5.7 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CDO76301.1 - 0.064 13.1 8.4 0.11 12.3 5.9 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 CDO76301.1 - 0.65 10.0 4.1 1.2 9.1 2.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain PALP PF00291.20 CDO76302.1 - 2.2e-28 99.3 0.0 3.1e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Fib_alpha PF08702.5 CDO76303.1 - 0.17 12.0 22.3 0.24 11.5 2.6 4.0 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 CDO76303.1 - 0.21 11.8 5.6 9.3 6.5 2.1 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 CDO76303.1 - 0.45 10.4 11.6 3.8 7.4 0.9 4.2 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3584 PF12128.3 CDO76303.1 - 0.52 7.5 33.2 0.035 11.4 19.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) CALCOCO1 PF07888.6 CDO76303.1 - 1.4 7.1 34.4 0.068 11.4 14.8 2.4 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 CDO76303.1 - 1.7 8.1 39.0 1.3 8.6 4.6 4.0 2 1 2 4 4 4 0 IncA protein ADIP PF11559.3 CDO76303.1 - 2 8.3 43.8 0.24 11.2 8.9 4.9 3 2 2 5 5 5 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 CDO76303.1 - 2.2 7.1 33.8 0.84 8.5 1.2 4.0 3 1 1 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 Sec8_exocyst PF04048.9 CDO76303.1 - 3.2 7.3 14.7 4.7 6.8 0.7 3.8 2 1 2 4 4 4 0 Sec8 exocyst complex component specific domain Filament PF00038.16 CDO76303.1 - 4 6.8 36.6 1.7 8.0 21.9 2.2 2 0 0 2 2 2 0 Intermediate filament protein DUF1515 PF07439.6 CDO76303.1 - 7.1 6.4 19.4 2.5 7.9 1.3 3.8 1 1 1 4 4 4 0 Protein of unknown function (DUF1515) FtsK_SpoIIIE PF01580.13 CDO76304.1 - 0.026 13.9 1.3 0.046 13.2 0.9 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pox_F11 PF04943.7 CDO76304.1 - 0.21 10.4 1.4 0.29 9.9 0.9 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein FUSC PF04632.7 CDO76304.1 - 0.57 8.5 11.3 0.73 8.1 7.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family LXG PF04740.7 CDO76304.1 - 0.74 9.5 7.7 0.12 12.2 2.6 1.7 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF2796 PF10986.3 CDO76304.1 - 9.8 6.1 11.1 18 5.2 7.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2796) Asp PF00026.18 CDO76305.1 - 6.9e-69 232.5 9.3 7.8e-69 232.3 6.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 CDO76305.1 - 0.015 14.8 0.1 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DUF1330 PF07045.6 CDO76307.1 - 0.039 13.8 0.5 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1330) rve PF00665.21 CDO76308.1 - 7.9e-08 32.4 0.0 2.1e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CDO76308.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 DDE domain PSD4 PF07631.6 CDO76310.1 - 0.061 13.6 0.1 0.2 12.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) RVT_1 PF00078.22 CDO76313.1 - 0.079 12.3 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 CDO76314.1 - 1.7e-16 59.3 9.8 0.00061 19.5 0.7 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat NLE PF08154.7 CDO76314.1 - 4.2e-16 58.7 0.0 8e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain DUF2204 PF09970.4 CDO76315.1 - 0.087 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) GPI-anchored PF10342.4 CDO76316.1 - 0.049 14.1 0.1 0.077 13.4 0.0 1.4 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Lipase_GDSL PF00657.17 CDO76317.1 - 4.6e-11 43.0 0.0 6.4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CDO76317.1 - 2.4e-07 31.0 3.7 8.4e-07 29.2 2.6 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DDE_1 PF03184.14 CDO76318.1 - 1.5e-25 89.6 0.0 2.4e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CDO76318.1 - 1e-10 41.2 0.0 3.3e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 CDO76318.1 - 0.0017 17.8 0.1 0.0041 16.6 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain SAP PF02037.22 CDO76318.1 - 0.013 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 SAP domain RasGAP_C PF03836.10 CDO76318.1 - 5.4 6.6 8.4 0.096 12.3 0.8 1.7 2 0 0 2 2 2 0 RasGAP C-terminus Pkinase PF00069.20 CDO76320.1 - 1.3e-05 24.4 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CDO76320.1 - 0.0067 16.1 0.4 0.022 14.4 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 CDO76321.1 - 0.0053 15.9 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Mpv17_PMP22 PF04117.7 CDO76323.1 - 1.4e-21 75.8 0.3 2.2e-21 75.2 0.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF4241 PF14025.1 CDO76324.1 - 0.00019 21.2 0.4 0.032 14.0 0.0 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF4241) Cys_rich_VLP PF14194.1 CDO76325.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich VLP PLA2_B PF01735.13 CDO76326.1 - 1.5e-75 254.2 0.0 3.1e-37 127.8 0.0 2.1 1 1 1 2 2 2 2 Lysophospholipase catalytic domain Glyco_hydro_28 PF00295.12 CDO76327.1 - 1.7e-28 99.5 2.5 2.4e-28 99.0 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 UBN_AB PF14075.1 CDO76328.1 - 2 8.0 11.5 9.6 5.8 3.8 2.4 3 0 0 3 3 3 0 Ubinuclein conserved middle domain TSA PF03249.8 CDO76328.1 - 5.4 5.4 5.7 12 4.3 3.9 1.5 1 0 0 1 1 1 0 Type specific antigen rve PF00665.21 CDO76329.1 - 4.7e-22 78.3 0.0 8.9e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO76329.1 - 2.3e-08 33.5 0.0 4.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CDO76329.1 - 0.0033 16.8 0.1 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Ferrochelatase PF00762.14 CDO76329.1 - 0.055 12.4 0.3 6.6 5.5 0.1 2.2 1 1 1 2 2 2 0 Ferrochelatase PMEI PF04043.10 CDO76330.1 - 0.052 13.4 2.3 0.12 12.2 0.2 1.9 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Velvet PF11754.3 CDO76331.1 - 5.7e-45 153.4 0.2 2.3e-44 151.4 0.1 1.9 1 1 0 1 1 1 1 Velvet factor DUF1777 PF08648.7 CDO76331.1 - 0.0074 16.0 24.1 0.012 15.3 16.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CDO76331.1 - 0.23 9.9 9.2 0.41 9.0 6.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DNA_pol_lambd_f PF10391.4 CDO76332.1 - 1.4e-19 69.3 0.3 4.7e-18 64.4 0.1 2.7 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 CDO76332.1 - 2.5e-18 66.1 0.8 1.3e-16 60.6 0.0 2.9 3 0 0 3 3 3 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 CDO76332.1 - 5.3e-18 64.4 0.0 2.7e-17 62.2 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 CDO76332.1 - 9.3e-14 51.3 0.2 2.1e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 CDO76332.1 - 0.0006 19.9 0.1 0.55 10.4 0.0 2.9 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.18 CDO76332.1 - 0.00084 18.9 0.1 0.0026 17.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 CDO76332.1 - 0.019 14.8 0.1 0.74 9.7 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Methyltransf_23 PF13489.1 CDO76333.1 - 1.1e-13 51.2 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO76333.1 - 1.8e-09 37.9 0.0 3.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO76333.1 - 2.3e-08 33.7 0.0 7.7e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO76333.1 - 3e-06 27.6 0.0 9.6e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO76333.1 - 9.1e-06 26.2 0.0 5.7e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CDO76333.1 - 2.7e-05 23.3 0.0 5.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 CDO76333.1 - 0.00024 21.3 0.0 0.00087 19.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CDO76333.1 - 0.0011 18.6 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Hypothetical methyltransferase FtsJ PF01728.14 CDO76333.1 - 0.0021 18.0 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 CDO76333.1 - 0.0021 18.0 0.0 0.024 14.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CDO76333.1 - 0.0027 16.9 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase DOT1 PF08123.8 CDO76333.1 - 0.0066 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Ubie_methyltran PF01209.13 CDO76333.1 - 0.03 13.4 0.0 0.18 10.8 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 CDO76333.1 - 0.043 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_M16 PF00675.15 CDO76334.1 - 6.2e-22 77.9 0.2 9.9e-22 77.2 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CDO76334.1 - 1.4e-09 37.9 0.0 5.8e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase M16 inactive domain PMEI PF04043.10 CDO76335.1 - 0.003 17.4 1.0 0.014 15.3 0.1 1.9 2 0 0 2 2 2 1 Plant invertase/pectin methylesterase inhibitor PMEI PF04043.10 CDO76336.1 - 0.2 11.5 0.9 0.84 9.5 0.1 1.9 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor CDC37_C PF08564.5 CDO76340.1 - 0.044 13.6 0.1 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Cdc37 C terminal domain Herpes_capsid PF06112.6 CDO76340.1 - 1.1 9.2 12.3 2.5 8.1 8.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RFC1 PF08519.7 CDO76341.1 - 8.3e-53 178.3 0.0 5.7e-51 172.3 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 CDO76341.1 - 5.1e-12 45.7 0.0 1.5e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 CDO76341.1 - 2.7e-10 40.5 0.1 8.6e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CDO76341.1 - 1.7e-05 23.7 0.2 0.00052 18.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 CDO76341.1 - 0.00039 20.1 0.0 0.00097 18.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CDO76341.1 - 0.0032 17.0 1.6 0.013 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CDO76341.1 - 0.0047 17.0 0.0 0.023 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CDO76341.1 - 0.007 17.1 0.5 0.049 14.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CDO76341.1 - 0.009 15.9 0.0 0.036 13.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CDO76341.1 - 0.0096 15.9 0.0 0.032 14.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CDO76341.1 - 0.014 14.5 0.0 0.059 12.4 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CDO76341.1 - 0.042 13.5 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 CDO76341.1 - 0.043 13.3 0.1 0.043 13.3 0.1 2.2 3 0 0 3 3 3 0 DNA polymerase III, delta subunit RNA_helicase PF00910.17 CDO76341.1 - 0.051 13.7 0.2 0.47 10.6 0.0 2.7 2 1 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 CDO76341.1 - 0.061 13.0 0.2 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 NTPase Asp PF00026.18 CDO76342.1 - 4.3e-78 262.7 0.5 5e-78 262.5 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO76342.1 - 1.7e-06 28.1 1.6 4.2e-05 23.5 0.8 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO76342.1 - 1.7e-05 25.2 0.2 0.0091 16.4 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 CDO76342.1 - 0.039 13.4 0.2 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DUF2243 PF10002.4 CDO76343.1 - 0.13 12.0 2.1 0.4 10.4 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2243) 53-BP1_Tudor PF09038.5 CDO76343.1 - 0.27 11.0 0.7 0.43 10.3 0.5 1.3 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor DUF1129 PF06570.6 CDO76343.1 - 0.41 9.9 2.2 0.79 8.9 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) GMC_oxred_N PF00732.14 CDO76344.1 - 9.8e-62 208.7 0.0 1.5e-61 208.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO76344.1 - 1.4e-34 119.4 0.0 2.7e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 CDO76344.1 - 2.6e-05 23.3 0.1 4e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CDO76344.1 - 0.0014 17.5 0.5 0.0068 15.2 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CDO76344.1 - 0.0039 17.0 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDO76344.1 - 0.0086 15.1 0.1 0.03 13.4 0.0 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 CDO76344.1 - 0.017 14.0 0.3 0.063 12.1 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 CDO76344.1 - 0.053 11.9 0.6 0.092 11.1 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 CDO76344.1 - 0.16 10.8 0.1 0.53 9.0 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 CDO76345.1 - 6.5e-19 67.8 39.4 1.1e-15 57.2 6.0 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO76345.1 - 3.4e-09 35.8 3.3 3.4e-09 35.8 2.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CDO76345.1 - 0.00021 19.6 1.8 0.00021 19.6 1.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.4 CDO76345.1 - 0.55 10.2 5.9 0.57 10.2 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) Suf PF05843.9 CDO76347.1 - 1e-75 255.1 7.2 5e-75 252.8 0.0 4.0 2 1 2 4 4 4 1 Suppressor of forked protein (Suf) Glyco_hydro_85 PF03644.8 CDO76347.1 - 2.9e-75 253.2 0.0 4.8e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 TPR_19 PF14559.1 CDO76347.1 - 1.9e-11 44.1 0.1 0.00066 19.9 0.1 4.8 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO76347.1 - 3.5e-10 39.6 5.4 0.23 12.2 0.0 7.3 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDO76347.1 - 1.1e-08 35.4 3.3 0.014 16.0 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CDO76347.1 - 2.6e-05 23.7 1.3 0.00013 21.5 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_15 PF13429.1 CDO76347.1 - 0.00078 18.5 0.7 0.04 12.9 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat FTCD_C PF04961.7 CDO76347.1 - 0.00091 18.6 0.3 0.004 16.5 0.0 2.0 2 0 0 2 2 2 1 Formiminotransferase-cyclodeaminase TPR_17 PF13431.1 CDO76347.1 - 0.033 14.3 0.1 0.61 10.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CDO76347.1 - 0.37 10.8 4.1 7.6 6.7 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Filament PF00038.16 CDO76347.1 - 0.89 8.9 4.6 0.19 11.1 0.3 1.8 2 0 0 2 2 2 0 Intermediate filament protein AAA PF00004.24 CDO76348.1 - 2e-49 167.1 0.0 8.3e-42 142.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDO76348.1 - 2.5e-08 34.1 0.0 1.5e-06 28.3 0.0 3.3 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 CDO76348.1 - 4e-06 26.3 0.0 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 CDO76348.1 - 1.5e-05 25.1 0.2 0.0045 17.1 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CDO76348.1 - 2.9e-05 23.7 0.2 0.0047 16.6 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 CDO76348.1 - 3.2e-05 23.9 0.0 8.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CDO76348.1 - 0.0016 18.2 0.1 0.015 15.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CDO76348.1 - 0.0035 17.2 2.1 0.017 15.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 CDO76348.1 - 0.005 17.6 0.3 0.026 15.3 0.0 2.5 3 0 0 3 3 1 1 AAA domain AAA_25 PF13481.1 CDO76348.1 - 0.0058 16.0 0.0 0.039 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.11 CDO76348.1 - 0.012 14.4 0.0 0.35 9.6 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activ_2 PF14532.1 CDO76348.1 - 0.018 15.1 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 CDO76348.1 - 0.023 14.6 0.7 0.056 13.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 CDO76348.1 - 0.024 13.8 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.1 CDO76348.1 - 0.036 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CDO76348.1 - 0.052 12.7 0.1 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CDO76348.1 - 0.054 12.5 0.0 0.19 10.7 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CDO76348.1 - 0.065 11.9 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Sigma54_activat PF00158.21 CDO76348.1 - 0.073 12.5 0.0 1.5 8.2 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_18 PF13238.1 CDO76348.1 - 0.074 13.3 0.0 0.074 13.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 CDO76348.1 - 0.12 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CDO76348.1 - 0.17 11.5 0.1 0.79 9.3 0.1 2.2 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.12 CDO76348.1 - 0.23 10.3 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PIF1 PF05970.9 CDO76348.1 - 0.32 9.8 0.0 0.57 9.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RRM_1 PF00076.17 CDO76349.1 - 9e-36 121.3 0.1 7.3e-17 60.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO76349.1 - 1.8e-27 95.0 0.2 1.9e-14 53.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO76349.1 - 3.8e-11 42.6 0.4 1.8e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO76349.1 - 0.041 13.6 0.0 4.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SNO PF01174.14 CDO76350.1 - 4.9e-29 101.2 0.0 8.1e-17 61.4 0.0 3.0 2 1 1 3 3 3 3 SNO glutamine amidotransferase family Daxx PF03344.10 CDO76352.1 - 0.035 12.5 9.1 0.065 11.7 6.3 1.3 1 0 0 1 1 1 0 Daxx Family DUF605 PF04652.11 CDO76352.1 - 0.07 12.5 12.5 0.092 12.1 8.7 1.2 1 0 0 1 1 1 0 Vta1 like Nop14 PF04147.7 CDO76352.1 - 0.17 9.8 9.9 0.24 9.2 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CDO76352.1 - 0.53 8.2 3.6 0.63 8.0 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 CDO76352.1 - 6 4.8 6.6 8.8 4.3 4.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_S10 PF00450.17 CDO76353.1 - 9.5e-74 249.0 0.9 8.5e-73 245.8 0.7 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.17 CDO76356.1 - 2.5e-70 237.7 0.0 1.4e-69 235.2 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.17 CDO76357.1 - 1.2e-49 169.5 0.0 2.3e-33 115.9 0.0 2.5 1 1 1 2 2 2 2 Serine carboxypeptidase FYDLN_acid PF09538.5 CDO76358.1 - 0.0011 19.5 14.3 0.0026 18.3 9.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) IBR PF01485.16 CDO76358.1 - 0.041 13.7 1.0 0.077 12.8 0.7 1.5 1 0 0 1 1 1 0 IBR domain Daxx PF03344.10 CDO76358.1 - 0.31 9.4 19.1 0.42 9.0 13.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 CDO76358.1 - 0.39 10.0 20.1 0.6 9.4 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 CDO76358.1 - 0.43 10.4 14.3 0.62 9.9 9.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2072 PF09845.4 CDO76358.1 - 0.73 9.7 12.6 1.5 8.7 8.7 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DDHD PF02862.12 CDO76358.1 - 0.89 9.3 8.4 1.5 8.5 5.9 1.4 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.8 CDO76358.1 - 0.92 8.9 6.3 1.3 8.4 4.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pox_Ag35 PF03286.9 CDO76358.1 - 2.1 7.8 16.4 4.2 6.8 11.3 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Trypan_PARP PF05887.6 CDO76358.1 - 2.3 8.0 18.0 1.9 8.3 9.2 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Spore_coat_CotO PF14153.1 CDO76358.1 - 2.4 7.5 20.7 3.7 6.9 14.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Protocadherin PF08374.6 CDO76358.1 - 2.7 7.5 6.6 4.3 6.9 4.5 1.3 1 0 0 1 1 1 0 Protocadherin DDRGK PF09756.4 CDO76358.1 - 4 6.8 22.6 6.2 6.1 15.7 1.2 1 0 0 1 1 1 0 DDRGK domain PPP4R2 PF09184.6 CDO76358.1 - 6.3 6.2 19.0 10 5.5 13.2 1.3 1 0 0 1 1 1 0 PPP4R2 Hid1 PF12722.2 CDO76358.1 - 8 3.9 8.8 10 3.6 6.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein adh_short PF00106.20 CDO76360.1 - 2.7e-15 56.7 0.6 5e-15 55.8 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO76360.1 - 1.9e-07 30.8 0.2 3.1e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CDO76360.1 - 0.00083 19.4 0.1 0.0022 18.0 0.1 1.7 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 CDO76360.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CDO76360.1 - 0.0063 15.9 0.1 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CDO76360.1 - 0.018 15.1 0.0 0.055 13.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.10 CDO76360.1 - 0.046 13.3 0.1 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus adh_short PF00106.20 CDO76361.1 - 7e-17 61.8 0.3 2.1e-16 60.3 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CDO76361.1 - 1.6e-07 31.2 0.2 2.4e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CDO76361.1 - 8.8e-06 25.6 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CDO76361.1 - 0.00015 21.8 0.2 0.0004 20.4 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 CDO76361.1 - 0.00076 18.9 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_28 PF03033.15 CDO76361.1 - 0.096 12.4 0.3 0.48 10.1 0.1 2.1 2 1 1 3 3 3 0 Glycosyltransferase family 28 N-terminal domain YjeF_N PF03853.10 CDO76361.1 - 0.12 12.0 0.1 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus adh_short PF00106.20 CDO76362.1 - 4.5e-05 23.4 0.0 0.00015 21.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CDO76362.1 - 0.049 13.2 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 KR domain CTX_RstB PF07459.6 CDO76362.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 CTX phage RstB protein MFS_1 PF07690.11 CDO76364.1 - 6e-19 67.9 20.6 4.3e-17 61.8 5.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CDO76364.1 - 3.1e-07 29.9 0.1 8.5e-07 28.4 0.1 1.7 1 0 0 1 1 1 1 Nodulin-like FGE-sulfatase PF03781.11 CDO76366.1 - 7.5e-20 71.3 1.2 1.2e-17 64.1 0.8 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 CDO76366.1 - 1.1e-08 35.4 1.0 2.3e-08 34.4 0.7 1.6 1 0 0 1 1 1 1 DinB superfamily Tcf25 PF04910.9 CDO76367.1 - 3.3e-70 236.8 0.0 7.4e-70 235.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.1 CDO76367.1 - 0.052 13.4 0.5 0.16 11.9 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat BSP_II PF05432.6 CDO76367.1 - 1.5 7.9 16.0 0.047 12.9 3.6 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Senescence_reg PF04520.8 CDO76367.1 - 4.6 7.7 13.3 3.5 8.1 3.6 2.6 2 0 0 2 2 2 0 Senescence regulator Sigma70_ner PF04546.8 CDO76367.1 - 9.4 5.7 15.2 1.1 8.8 1.0 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region AIRC PF00731.15 CDO76368.1 - 3.6e-64 214.5 1.6 8.4e-64 213.3 1.1 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 CDO76368.1 - 8.1e-60 201.0 0.0 1.2e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CDO76368.1 - 5.2e-14 52.4 0.0 9.6e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CDO76368.1 - 4.7e-05 22.7 0.0 8.2e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 CDO76368.1 - 0.00017 20.4 0.0 0.056 12.1 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CDO76368.1 - 0.0013 18.1 0.0 0.0061 15.9 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CDO76368.1 - 0.021 14.6 0.0 0.059 13.2 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain Rsa3 PF14615.1 CDO76369.1 - 3.4e-11 42.2 0.0 4.8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 TFIIF_alpha PF05793.7 CDO76369.1 - 0.015 13.7 12.7 0.018 13.4 8.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1675 PF07897.6 CDO76369.1 - 0.21 11.4 6.9 0.26 11.1 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Cwf_Cwc_15 PF04889.7 CDO76369.1 - 2.5 7.7 8.8 5.4 6.6 6.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4551 PF15087.1 CDO76369.1 - 5.3 5.2 9.2 6.3 5.0 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3827 PF12877.2 CDO76369.1 - 5.7 4.9 14.3 7.6 4.4 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Npa1 PF11707.3 CDO76370.1 - 6.7e-73 245.5 0.4 9.6e-72 241.7 0.0 2.9 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 CDO76370.1 - 0.0012 19.0 0.0 0.0095 16.1 0.0 2.5 2 0 0 2 2 2 1 Creb binding TPR_19 PF14559.1 CDO76370.1 - 0.1 12.9 3.9 0.41 11.0 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Copper-bind PF00127.15 CDO76371.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family p450 PF00067.17 CDO76372.1 - 2.1e-57 194.6 0.0 4.3e-56 190.3 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 HD PF01966.17 CDO76374.1 - 5.3e-11 42.5 0.4 1.9e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 HD domain Exo_endo_phos PF03372.18 CDO76375.1 - 6.3e-25 88.5 0.1 1.5e-24 87.3 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PQQ_2 PF13360.1 CDO76375.1 - 0.057 12.8 0.1 0.36 10.2 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain RPM2 PF08579.6 CDO76376.1 - 0.033 14.3 0.0 2 8.5 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.1 CDO76376.1 - 0.15 12.0 0.0 6.9 6.7 0.0 2.9 3 0 0 3 3 3 0 PPR repeat family PPR_3 PF13812.1 CDO76376.1 - 0.18 12.1 1.5 35 5.0 0.0 3.8 4 0 0 4 4 4 0 Pentatricopeptide repeat domain DUF2716 PF10898.3 CDO76377.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) Cellulase PF00150.13 CDO76379.1 - 1.6e-06 27.5 0.1 2.3e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) UPRTase PF14681.1 CDO76380.1 - 2.1e-59 200.2 0.0 2.9e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase EMG1 PF03587.9 CDO76380.1 - 1.3e-46 158.4 0.0 6.9e-34 116.9 0.0 2.2 2 0 0 2 2 2 2 EMG1/NEP1 methyltransferase Pribosyltran PF00156.22 CDO76380.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain CRAL_TRIO PF00650.15 CDO76381.1 - 8.2e-30 103.3 0.0 3.9e-29 101.1 0.0 2.0 3 0 0 3 3 3 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CDO76381.1 - 2.4e-14 53.1 1.0 7e-14 51.6 0.2 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain RNase_T PF00929.19 CDO76386.1 - 3.4e-22 79.4 0.0 5.1e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CDO76386.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.6 1 1 0 1 1 1 0 3'-5' exonuclease Peptidase_S10 PF00450.17 CDO76389.1 - 2.8e-58 198.0 0.2 3.6e-58 197.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 CDO76389.1 - 0.038 13.7 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family TpcC PF12642.2 CDO76389.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Conjugative transposon protein TcpC Peptidase_S10 PF00450.17 CDO76390.1 - 3.5e-88 296.5 0.0 9.2e-88 295.1 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase OapA_N PF08525.6 CDO76391.1 - 1.4 8.8 0.1 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif MULE PF10551.4 CDO76392.1 - 7.4e-07 29.2 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Chromo PF00385.19 CDO76393.1 - 7.5e-09 35.1 0.0 1.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Herpes_UL25 PF01499.11 CDO76393.1 - 0.0048 15.2 0.7 0.0053 15.1 0.5 1.1 1 0 0 1 1 1 1 Herpesvirus UL25 family ATP-synt_E PF05680.7 CDO76393.1 - 0.58 10.1 6.4 3 7.8 4.8 1.9 2 0 0 2 2 2 0 ATP synthase E chain Glypican PF01153.14 CDO76393.1 - 1.1 7.7 3.5 1.4 7.4 2.4 1.1 1 0 0 1 1 1 0 Glypican DUF755 PF05501.6 CDO76393.1 - 1.4 8.9 6.8 2 8.4 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Peptidase_S49_N PF08496.5 CDO76393.1 - 2.2 8.0 7.7 3.1 7.5 5.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3886 PF13025.1 CDO76393.1 - 2.9 7.9 17.5 5 7.1 12.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) U79_P34 PF03064.11 CDO76393.1 - 3 7.3 9.4 4 6.8 6.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SPX PF03105.14 CDO76393.1 - 3.5 7.3 7.3 5.2 6.7 5.1 1.2 1 0 0 1 1 1 0 SPX domain TSA PF03249.8 CDO76393.1 - 4.3 5.7 5.3 5.4 5.4 3.7 1.1 1 0 0 1 1 1 0 Type specific antigen YscO PF07321.7 CDO76393.1 - 5.4 6.8 19.9 9.6 6.0 13.8 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO DUF3317 PF11779.3 CDO76395.1 - 3.3e-10 39.2 2.9 5.7e-10 38.4 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Epiglycanin_C PF14654.1 CDO76395.1 - 0.034 14.1 0.2 0.056 13.4 0.1 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Abhydrolase_6 PF12697.2 CDO76397.1 - 0.014 15.2 3.7 0.014 15.3 1.7 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family UBX PF00789.15 CDO76399.1 - 1.3e-07 31.5 0.0 2.9e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CDO76399.1 - 1.6e-07 30.7 0.0 2.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Polyoma_coat2 PF00761.15 CDO76399.1 - 0.45 9.9 1.7 0.72 9.2 1.2 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein CUE PF02845.11 CDO76400.1 - 7.4e-11 41.3 0.0 1.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain PAX PF00292.13 CDO76400.1 - 0.071 12.8 0.1 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 'Paired box' domain NVEALA PF14055.1 CDO76400.1 - 0.12 12.1 1.5 11 5.8 0.1 2.4 2 0 0 2 2 2 0 NVEALA protein Bacteriocin_IIc PF10439.4 CDO76401.1 - 4 7.6 6.2 13 6.0 4.3 2.0 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Abhydrolase_5 PF12695.2 CDO76402.1 - 5.8e-22 78.0 0.0 9.1e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO76402.1 - 1.5e-18 67.4 0.2 7.6e-17 61.9 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO76402.1 - 9.2e-10 38.4 0.0 3.3e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 CDO76402.1 - 4.7e-06 26.4 0.0 0.0016 18.1 0.0 2.4 3 0 0 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 CDO76402.1 - 0.00017 20.2 0.2 0.072 11.5 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 CDO76402.1 - 0.0018 17.7 0.0 0.066 12.6 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 CDO76402.1 - 0.0042 16.5 0.0 1.5 8.2 0.0 2.9 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CDO76402.1 - 0.011 15.0 0.0 0.09 11.9 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF2305 PF10230.4 CDO76402.1 - 0.017 14.5 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DLH PF01738.13 CDO76402.1 - 0.018 14.2 0.0 0.094 11.9 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Pkinase PF00069.20 CDO76403.1 - 1.4e-48 165.3 0.0 3.1e-48 164.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76403.1 - 1.4e-25 89.8 0.0 3.4e-18 65.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CDO76403.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CDO76403.1 - 0.01 14.8 0.1 0.77 8.6 0.0 2.9 2 1 0 2 2 2 0 Kinase-like APH PF01636.18 CDO76403.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CDO76403.1 - 0.065 12.0 0.0 0.099 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Prenylcys_lyase PF07156.9 CDO76404.1 - 1.2e-39 136.2 0.0 1.8e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 CDO76404.1 - 1.2e-08 34.8 0.0 2.5e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CDO76404.1 - 0.0011 18.8 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 CDO76404.1 - 0.006 15.5 0.2 0.02 13.7 0.1 1.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CDO76404.1 - 0.059 13.2 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDO76404.1 - 0.13 12.3 0.0 0.95 9.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CDO76404.1 - 0.39 9.5 1.1 0.56 8.9 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4598 PF15370.1 CDO76405.1 - 1.7e-12 47.5 7.7 1.2e-11 44.8 5.4 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) CDC45 PF02724.9 CDO76405.1 - 0.2 9.6 9.2 0.29 9.1 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CDO76405.1 - 0.25 9.2 6.0 0.27 9.1 4.2 1.2 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 CDO76405.1 - 1.2 8.6 8.0 0.15 11.6 2.4 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Prenylcys_lyase PF07156.9 CDO76406.1 - 2.9e-42 144.8 0.0 4e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 CDO76406.1 - 1.9e-10 40.5 0.2 5e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CDO76406.1 - 1.7e-06 27.3 0.1 0.0052 15.9 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 CDO76406.1 - 0.00016 20.6 1.0 0.0065 15.4 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CDO76406.1 - 0.00034 20.4 0.2 0.0019 17.9 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CDO76406.1 - 0.00044 20.3 0.1 0.49 10.4 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDO76406.1 - 0.011 15.6 0.2 0.051 13.4 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO76406.1 - 0.1 11.0 0.2 0.15 10.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 CDO76406.1 - 0.15 10.8 1.4 0.22 10.3 1.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 CDO76406.1 - 0.17 10.9 0.1 0.38 9.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pro-kuma_activ PF09286.6 CDO76407.1 - 1.7e-41 141.5 0.0 5.8e-41 139.8 0.0 1.9 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO76407.1 - 1.8e-12 46.9 0.5 3e-12 46.2 0.3 1.3 1 0 0 1 1 1 1 Subtilase family Ferric_reduct PF01794.14 CDO76408.1 - 1.9e-12 47.3 8.8 1.9e-12 47.3 6.1 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CDO76408.1 - 8.5e-12 44.8 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CDO76408.1 - 1e-08 35.2 0.0 3e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Fumarate_red_C PF02300.12 CDO76408.1 - 0.19 11.6 6.2 3.1 7.6 1.5 2.4 2 0 0 2 2 2 0 Fumarate reductase subunit C Glyco_hydro_cc PF11790.3 CDO76409.1 - 6.7e-60 202.4 1.8 9e-60 202.0 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Cellulase PF00150.13 CDO76409.1 - 0.037 13.2 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) EF-hand_7 PF13499.1 CDO76410.1 - 1.9e-12 47.1 0.0 7.2e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CDO76410.1 - 5.5e-12 44.5 0.2 6.4e-05 22.5 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CDO76410.1 - 2e-10 39.1 0.1 0.00045 19.3 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 CDO76410.1 - 5.2e-06 26.2 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CDO76410.1 - 5.8e-06 25.8 0.0 0.00038 19.9 0.0 3.3 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.1 CDO76410.1 - 0.0058 15.9 0.2 1.6 8.2 0.1 2.7 2 0 0 2 2 2 2 EF hand UPF0154 PF03672.8 CDO76410.1 - 0.0076 15.8 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) YrhK PF14145.1 CDO76411.1 - 4.5e-05 23.0 17.0 0.29 10.8 1.6 4.2 3 1 0 3 3 3 3 YrhK-like protein Glyco_hydro_61 PF03443.9 CDO76412.1 - 3.3e-52 177.4 0.0 4.7e-51 173.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Zn_clus PF00172.13 CDO76413.1 - 3.1e-05 23.8 1.2 4.7e-05 23.2 0.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 CDO76414.1 - 4.4e-57 193.6 0.0 3.2e-42 144.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Isochorismatase PF00857.15 CDO76415.1 - 1.6e-20 73.7 0.0 2.2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Ras PF00071.17 CDO76416.1 - 3.6e-26 91.4 0.0 4.8e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO76416.1 - 0.0021 18.5 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein WD40 PF00400.27 CDO76417.1 - 3.9e-70 229.4 18.9 5.8e-11 41.8 0.0 8.6 8 0 0 8 8 8 8 WD domain, G-beta repeat PD40 PF07676.7 CDO76417.1 - 2e-08 33.6 3.6 8.1 6.2 0.0 7.5 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 CDO76417.1 - 7.8e-08 32.2 0.0 0.00025 20.8 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 CDO76417.1 - 0.00084 18.8 0.7 0.25 10.7 0.1 2.9 1 1 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 CDO76417.1 - 0.0064 15.7 11.5 0.18 11.1 0.0 5.6 6 0 0 6 6 6 2 Proteasome subunit A N-terminal signature DUF3312 PF11768.3 CDO76417.1 - 0.02 13.1 0.0 1.9 6.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) Nbas_N PF15492.1 CDO76417.1 - 0.051 12.6 0.1 24 3.8 0.0 3.8 4 1 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Zn_clus PF00172.13 CDO76419.1 - 0.033 14.1 7.7 0.068 13.0 5.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-synt_E PF05680.7 CDO76419.1 - 2.3 8.2 7.6 4.2 7.3 5.2 1.4 1 0 0 1 1 1 0 ATP synthase E chain U79_P34 PF03064.11 CDO76419.1 - 2.9 7.3 8.6 3.9 6.9 6.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_S49_N PF08496.5 CDO76419.1 - 3.5 7.4 7.5 6.9 6.4 5.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Retrotrans_gag PF03732.12 CDO76420.1 - 5.5e-14 51.9 0.0 1.1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 CDO76420.1 - 0.034 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO76420.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 CDO76420.1 - 0.21 11.2 0.3 0.33 10.6 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle RAP1 PF07218.6 CDO76420.1 - 0.56 8.2 5.4 0.73 7.8 3.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Methyltransf_23 PF13489.1 CDO76421.1 - 1.9e-20 73.2 0.0 3.1e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO76421.1 - 3.1e-17 62.8 0.0 4.7e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO76421.1 - 5e-13 49.3 0.0 1.6e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO76421.1 - 2.8e-12 46.4 0.0 2.1e-11 43.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO76421.1 - 1.3e-11 45.0 0.0 2.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO76421.1 - 3.2e-06 27.1 0.0 6.7e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CDO76421.1 - 1.3e-05 24.4 0.0 0.0002 20.5 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CDO76421.1 - 2.7e-05 24.4 0.0 4.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CDO76421.1 - 0.00049 18.9 0.1 0.0068 15.1 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 CDO76421.1 - 0.037 13.4 0.1 0.14 11.5 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.1 CDO76421.1 - 0.05 13.2 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.8 CDO76421.1 - 0.076 13.1 0.1 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PrmA PF06325.8 CDO76421.1 - 0.12 11.4 0.2 0.23 10.5 0.1 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 CDO76421.1 - 0.18 11.1 0.2 1.1 8.6 0.1 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Glyco_hydro_18 PF00704.23 CDO76422.1 - 2.6e-08 33.7 0.3 3.4e-08 33.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 F-box-like PF12937.2 CDO76424.1 - 3.4e-05 23.4 0.2 0.00079 19.1 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDO76424.1 - 0.031 13.9 3.4 3.1 7.5 0.0 4.2 4 0 0 4 4 4 0 F-box domain Pkinase PF00069.20 CDO76425.1 - 4.7e-46 157.0 0.0 6.6e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76425.1 - 7.4e-39 133.3 0.0 1.1e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Spt5_N PF11942.3 CDO76425.1 - 0.003 18.1 0.9 0.003 18.1 0.7 5.6 2 1 3 5 5 5 1 Spt5 transcription elongation factor, acidic N-terminal APH PF01636.18 CDO76425.1 - 0.0094 15.7 0.1 0.026 14.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family SAP PF02037.22 CDO76425.1 - 0.0095 15.4 0.1 0.035 13.6 0.1 2.0 2 0 0 2 2 2 1 SAP domain Seadorna_VP7 PF07387.6 CDO76425.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Lin-8 PF03353.10 CDO76425.1 - 0.53 9.5 2.6 1.4 8.1 1.8 1.7 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RCC1 PF00415.13 CDO76426.1 - 3.8e-56 187.1 7.7 3.5e-08 33.5 0.0 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDO76426.1 - 2.1e-33 113.1 32.7 1.1e-06 28.0 0.0 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat AMP-binding PF00501.23 CDO76427.1 - 1.1e-52 178.9 0.0 9.4e-28 96.7 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CDO76427.1 - 8.9e-20 71.4 1.1 1.6e-19 70.6 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 CDO76429.1 - 9.8e-21 74.0 0.0 1.2e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CDO76429.1 - 0.00014 20.5 0.0 0.00021 20.0 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase AAA PF00004.24 CDO76430.1 - 1.9e-14 53.9 0.0 4.2e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDO76430.1 - 3.4e-06 26.8 0.0 0.00014 21.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CDO76430.1 - 5.6e-06 25.5 0.0 1.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CDO76430.1 - 1e-05 25.1 0.0 5e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 CDO76430.1 - 2.3e-05 25.2 0.0 7.6e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CDO76430.1 - 5.4e-05 22.0 0.0 0.00037 19.3 0.0 2.0 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CDO76430.1 - 5.4e-05 23.3 0.0 0.00079 19.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CDO76430.1 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CDO76430.1 - 0.00031 20.6 0.1 0.098 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CDO76430.1 - 0.00048 20.0 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CDO76430.1 - 0.00093 18.6 0.2 0.35 10.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CDO76430.1 - 0.0018 18.2 0.0 0.0092 15.9 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CDO76430.1 - 0.0042 17.3 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CDO76430.1 - 0.0078 16.1 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CDO76430.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 CDO76430.1 - 0.014 15.1 0.1 0.13 11.9 0.0 2.2 1 1 1 2 2 2 0 NTPase Zeta_toxin PF06414.7 CDO76430.1 - 0.014 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 CDO76430.1 - 0.017 14.7 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CDO76430.1 - 0.055 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 CDO76430.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 CDO76430.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 CDO76430.1 - 0.16 11.6 0.0 2.9 7.5 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase Clp1 PF06807.9 CDO76431.1 - 6.7e-19 68.4 0.0 5.1e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CDO76431.1 - 2e-06 27.5 0.0 8.9e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CDO76431.1 - 0.037 14.0 0.0 0.28 11.1 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 CDO76431.1 - 0.051 13.7 0.0 0.16 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 CDO76431.1 - 0.053 12.7 0.0 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CDO76431.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 CDO76431.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein S-AdoMet_synt_C PF02773.11 CDO76432.1 - 1.5e-75 251.4 0.3 3.1e-75 250.4 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CDO76432.1 - 2.7e-50 169.3 0.0 4.8e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CDO76432.1 - 5.9e-44 148.3 1.2 6.8e-44 148.1 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Myotub-related PF06602.9 CDO76433.1 - 7.9e-127 422.8 0.0 1.1e-126 422.3 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 CDO76433.1 - 0.067 12.5 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CDO76433.1 - 0.082 13.1 0.3 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Cytochrome_CBB3 PF13442.1 CDO76434.1 - 0.061 13.4 0.2 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Zn-ribbon_8 PF09723.5 CDO76434.1 - 0.54 10.2 3.0 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain MFS_1 PF07690.11 CDO76435.1 - 8.3e-14 51.0 39.0 8.3e-14 51.0 27.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sigma_reg_N PF13800.1 CDO76435.1 - 0.13 12.3 1.8 0.91 9.5 0.0 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF1616 PF07760.6 CDO76435.1 - 0.23 10.5 10.6 0.48 9.5 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) Pox_A14 PF05767.7 CDO76435.1 - 0.57 10.1 5.3 3.2 7.7 0.3 3.5 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 Baculo_11_kDa PF06143.6 CDO76435.1 - 0.57 9.5 2.1 12 5.3 1.5 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF4191 PF13829.1 CDO76435.1 - 1.1 8.2 3.1 4.5 6.3 2.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Use1 PF09753.4 CDO76435.1 - 2.8 7.3 4.7 4.7 6.5 3.2 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 Pyr_redox_2 PF07992.9 CDO76438.1 - 7.7e-21 74.8 0.0 1.1e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO76438.1 - 1.2e-11 44.8 0.0 1.1e-07 32.1 0.0 4.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 CDO76438.1 - 7.3e-11 40.5 0.9 2e-05 23.5 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CDO76438.1 - 3.5e-09 36.6 0.0 0.0012 18.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CDO76438.1 - 1.5e-07 30.6 0.7 0.0047 16.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CDO76438.1 - 2.9e-07 29.5 1.4 0.00026 20.1 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CDO76438.1 - 1e-06 28.2 0.5 0.048 13.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.2 CDO76438.1 - 0.016 14.9 1.3 2.2 8.0 0.1 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand NAD_binding_7 PF13241.1 CDO76438.1 - 0.057 13.6 0.0 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding WD40 PF00400.27 CDO76439.1 - 6.1e-43 143.2 9.2 1.1e-08 34.5 0.0 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CDO76439.1 - 0.023 14.4 0.0 22 4.7 0.0 3.4 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 CDO76439.1 - 0.3 8.8 0.6 9.6 3.8 0.0 2.7 3 0 0 3 3 3 0 IKI3 family Gti1_Pac2 PF09729.4 CDO76440.1 - 1e-27 97.0 1.4 1.4e-25 90.1 1.0 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family cwf18 PF08315.7 CDO76441.1 - 3.1e-09 37.3 6.3 2e-08 34.7 4.4 2.0 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor LepA_C PF06421.7 CDO76442.1 - 1.7e-39 134.0 0.0 2.7e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CDO76442.1 - 5.5e-13 48.6 0.0 1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CDO76442.1 - 1.6e-06 28.1 0.0 3.2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CDO76442.1 - 1.6e-05 24.6 0.0 3.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Cupredoxin_1 PF13473.1 CDO76443.1 - 0.02 14.7 0.1 0.023 14.5 0.0 1.2 1 1 0 1 1 1 0 Cupredoxin-like domain Ecl1 PF12855.2 CDO76444.1 - 0.031 13.5 0.2 0.059 12.6 0.1 1.4 1 0 0 1 1 1 0 Life-span regulatory factor DUF329 PF03884.9 CDO76444.1 - 0.095 12.2 0.2 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF329) Vps54 PF07928.7 CDO76445.1 - 1.2e-52 177.6 1.6 3.9e-52 175.9 1.1 1.9 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.4 CDO76445.1 - 1e-05 25.4 0.3 3.1e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF2450 PF10475.4 CDO76445.1 - 0.0002 20.3 0.0 0.00039 19.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) RVT_1 PF00078.22 CDO76446.1 - 2.4e-26 92.4 0.0 3.7e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO76446.1 - 2.1e-11 44.2 0.0 6.3e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 CDO76446.1 - 3.4e-09 36.3 0.0 9.1e-09 34.9 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CDO76446.1 - 6.6e-06 26.2 4.6 2.5e-05 24.3 3.2 2.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Chromo PF00385.19 CDO76448.1 - 6.9e-08 32.0 0.1 1.2e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SelB-wing_2 PF09106.6 CDO76448.1 - 0.08 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF4407 PF14362.1 CDO76449.1 - 2.7 6.8 16.0 3.7 6.4 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 CDO76449.1 - 4 7.2 23.2 1.6 8.4 3.0 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Bap31 PF05529.7 CDO76449.1 - 6.2 6.2 5.6 3.9 6.8 1.8 2.1 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Retrotrans_gag PF03732.12 CDO76450.1 - 2.1e-08 34.1 0.0 4.9e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 CDO76450.1 - 0.0054 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 CDO76450.1 - 0.17 11.6 0.5 0.3 10.7 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.6 CDO76451.1 - 1.1e-07 31.8 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CDO76451.1 - 3.1e-07 30.7 0.0 6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO76451.1 - 1.2e-06 28.1 0.0 2.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 CDO76451.1 - 0.0014 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A2B PF12384.3 CDO76451.1 - 0.0048 16.2 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase zf-RVT PF13966.1 CDO76452.1 - 4.3e-05 23.7 0.0 7.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 CDO76452.1 - 7.6e-05 23.0 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 RNase H Abhydrolase_3 PF07859.8 CDO76453.1 - 2.1e-50 171.2 0.1 3e-50 170.7 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CDO76453.1 - 0.00013 20.8 0.0 0.00039 19.2 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Histone PF00125.19 CDO76454.1 - 5.3e-22 77.7 0.1 7.7e-22 77.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CDO76454.1 - 5.3e-06 26.3 1.4 6.2e-06 26.1 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CDO76454.1 - 0.00025 21.2 0.0 0.00046 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.6 CDO76454.1 - 0.074 12.4 0.1 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein DUF1018 PF06252.7 CDO76454.1 - 0.087 13.3 0.2 0.12 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Histone PF00125.19 CDO76455.1 - 1.5e-26 92.2 0.0 1.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CDO76455.1 - 1.5e-06 28.1 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HECT_2 PF09814.4 CDO76456.1 - 7.8e-35 120.2 0.0 6e-34 117.3 0.0 2.0 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RRM_1 PF00076.17 CDO76457.1 - 8.7e-31 105.3 0.0 2e-19 68.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO76457.1 - 1.3e-24 85.9 0.0 7e-14 51.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO76457.1 - 4e-11 42.5 0.0 1.4e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.19 CDO76458.1 - 1.5e-26 92.2 0.0 2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CDO76458.1 - 1.5e-06 28.1 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CDO76459.1 - 4.7e-18 65.0 0.1 8.5e-18 64.2 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CDO76459.1 - 3.9e-05 23.6 0.1 9.9e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CDO76459.1 - 0.00028 21.0 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.6 CDO76459.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Herpes_BLLF1 PF05109.8 CDO76459.1 - 0.12 10.2 2.4 0.16 9.9 1.7 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) GST_C_3 PF14497.1 CDO76460.1 - 1.4e-10 41.5 0.0 2.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO76460.1 - 3.3e-05 23.8 0.1 7.4e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CDO76460.1 - 0.00013 22.1 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO76460.1 - 0.00063 19.8 0.1 0.0022 18.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO76460.1 - 0.005 16.7 0.0 0.0087 15.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Homoserine_dh PF00742.14 CDO76461.1 - 5.9e-46 156.3 0.0 7.7e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CDO76461.1 - 7.5e-15 55.3 0.0 1.4e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PHB_acc_N PF07879.6 CDO76461.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain WD40 PF00400.27 CDO76462.1 - 1.2e-17 63.0 8.4 3e-07 30.0 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat VIT1 PF01988.14 CDO76462.1 - 1.4 8.3 5.1 3.8 6.9 3.5 1.7 1 1 0 1 1 1 0 VIT family GRAB PF10375.4 CDO76463.1 - 3.1e-06 26.6 0.6 5.8e-06 25.7 0.4 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.15 CDO76463.1 - 0.0015 18.0 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 GRIP domain CENP-F_leu_zip PF10473.4 CDO76463.1 - 0.069 13.0 52.1 0.16 11.8 12.1 4.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.8 CDO76463.1 - 0.37 10.6 7.1 1.6 8.5 0.8 3.3 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Calici_MSP PF05752.6 CDO76463.1 - 0.5 9.9 4.1 0.93 9.0 1.3 2.3 2 0 0 2 2 2 0 Calicivirus minor structural protein DUF1054 PF06335.7 CDO76463.1 - 0.63 9.6 7.0 0.11 12.1 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) DUF1722 PF08349.6 CDO76463.1 - 1.6 8.6 5.6 5 7.0 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1722) ERG2_Sigma1R PF04622.7 CDO76464.1 - 2.8e-80 268.6 0.0 3.4e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ERG2_Sigma1R PF04622.7 CDO76466.1 - 2.2e-82 275.4 0.0 5.1e-82 274.3 0.0 1.6 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein VPR PF00522.13 CDO76466.1 - 0.0027 17.4 0.1 4.2 7.2 0.0 3.0 3 0 0 3 3 3 2 VPR/VPX protein DUF2207 PF09972.4 CDO76466.1 - 0.57 8.6 1.7 0.91 8.0 1.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPC25 PF06703.6 CDO76467.1 - 2.2e-38 131.4 0.0 2.5e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) PNRC PF15365.1 CDO76468.1 - 0.00028 20.8 1.0 0.00028 20.8 0.7 5.1 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator Phage_integrase PF00589.17 CDO76469.1 - 0.0077 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 CDO76472.1 - 0.03 13.6 0.1 0.042 13.1 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CDO76473.1 - 1.3e-12 47.5 0.2 6.5e-12 45.3 0.0 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO76473.1 - 0.0071 16.2 0.4 0.011 15.6 0.3 1.3 1 0 0 1 1 1 1 Zinc knuckle Macoilin PF09726.4 CDO76473.1 - 0.84 7.8 9.5 1.1 7.4 6.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2413 PF10310.4 CDO76473.1 - 4.7 5.9 14.8 0.14 10.9 5.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Raptor_N PF14538.1 CDO76475.1 - 3.1e-61 205.7 0.0 6.5e-61 204.6 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 CDO76475.1 - 7.5e-06 25.5 0.4 0.00034 20.4 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat WD40 PF00400.27 CDO76475.1 - 0.00018 21.2 4.2 7.9 6.5 0.2 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT_2 PF13646.1 CDO76475.1 - 0.0003 20.9 0.3 0.0031 17.7 0.0 2.7 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 CDO76475.1 - 0.0023 18.3 0.1 0.0023 18.3 0.1 3.7 4 0 0 4 4 4 1 HEAT-like repeat Arm PF00514.18 CDO76475.1 - 0.061 13.1 0.3 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 CDO76475.1 - 0.079 12.8 0.0 1.1 9.0 0.0 2.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Peptidase_C14 PF00656.17 CDO76475.1 - 0.27 10.9 0.0 0.46 10.1 0.0 1.3 1 0 0 1 1 1 0 Caspase domain Dynactin PF12455.3 CDO76476.1 - 6.3e-86 287.6 4.1 6.3e-86 287.6 2.9 3.4 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 CDO76476.1 - 7.4e-24 83.2 0.4 1.9e-23 81.9 0.2 1.7 2 0 0 2 2 2 1 CAP-Gly domain ABC_tran PF00005.22 CDO76478.1 - 5.2e-51 172.5 0.0 1.8e-26 93.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CDO76478.1 - 1.4e-23 83.4 45.7 1e-15 57.6 17.5 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CDO76478.1 - 1.1e-16 61.6 3.9 1.6e-06 28.2 0.0 4.3 3 1 1 4 4 4 3 AAA domain AAA_23 PF13476.1 CDO76478.1 - 2.7e-07 31.1 3.2 0.0026 18.1 0.4 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CDO76478.1 - 1.1e-05 24.8 0.6 0.12 11.9 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CDO76478.1 - 0.0018 17.4 0.2 1.6 7.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 CDO76478.1 - 0.0032 16.7 4.4 1.9 7.6 0.1 3.9 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain SRP54 PF00448.17 CDO76478.1 - 0.0034 16.8 1.1 1.2 8.5 0.1 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_15 PF13175.1 CDO76478.1 - 0.0068 15.4 0.0 3 6.7 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 CDO76478.1 - 0.0099 15.4 0.3 8.4 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 CDO76478.1 - 0.037 13.1 0.0 5.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.10 CDO76478.1 - 0.068 11.8 0.0 6.8 5.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA PF00004.24 CDO76478.1 - 0.07 13.3 0.4 13 6.0 0.1 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MukB PF04310.7 CDO76478.1 - 0.074 12.3 0.3 11 5.2 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal T2SE PF00437.15 CDO76478.1 - 0.085 11.7 0.0 11 4.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.1 CDO76478.1 - 0.11 12.4 0.3 11 5.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CDO76478.1 - 0.17 12.0 2.5 15 5.7 0.0 3.1 2 2 0 2 2 2 0 AAA domain AAA_13 PF13166.1 CDO76478.1 - 1.4 7.3 0.8 28 2.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain GRAM PF02893.15 CDO76479.1 - 1.3e-15 56.6 0.0 2.4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Pkinase PF00069.20 CDO76480.1 - 1.5e-58 198.0 0.0 8e-58 195.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76480.1 - 6e-26 91.0 0.0 2.1e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 CDO76480.1 - 2.3e-05 24.8 5.2 2.3e-05 24.8 3.6 3.7 3 1 0 3 3 3 1 Protein kinase C terminal domain Kdo PF06293.9 CDO76480.1 - 0.0027 16.8 0.0 0.0052 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PX PF00787.19 CDO76480.1 - 0.0046 16.7 0.0 0.05 13.3 0.0 2.5 1 1 0 1 1 1 1 PX domain Kinase-like PF14531.1 CDO76480.1 - 0.025 13.5 0.0 0.52 9.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Thioredoxin PF00085.15 CDO76482.1 - 1.9e-25 88.5 0.4 2.2e-20 72.2 0.1 2.0 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CDO76482.1 - 5.2e-06 26.6 0.0 8.6e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDO76482.1 - 6.2e-06 26.2 0.1 9.9e-06 25.5 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CDO76482.1 - 0.0001 21.8 0.1 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CDO76482.1 - 0.00022 20.9 0.1 0.00038 20.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CDO76482.1 - 0.015 14.8 0.2 0.035 13.6 0.2 1.6 1 1 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.1 CDO76482.1 - 0.086 12.8 0.1 0.15 12.0 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like DUF2847 PF11009.3 CDO76482.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) Glutaredoxin PF00462.19 CDO76482.1 - 0.15 12.1 0.1 0.35 10.8 0.1 1.6 1 1 0 1 1 1 0 Glutaredoxin Glyco_hydro_2 PF00703.16 CDO76483.1 - 0.0013 19.1 0.1 0.0052 17.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 CDO76483.1 - 0.0071 15.9 0.0 0.02 14.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Chitin_synth_2 PF03142.10 CDO76484.1 - 2.4e-128 428.8 0.0 3.6e-128 428.2 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CDO76484.1 - 5.4e-07 29.5 1.1 1.1e-06 28.5 0.8 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CDO76484.1 - 0.0011 18.7 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 CDO76485.1 - 1.1e-118 396.9 0.0 2.1e-118 396.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.23 CDO76485.1 - 3.3e-06 26.8 0.1 0.00017 21.3 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 CDO76485.1 - 0.003 17.4 0.1 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CDO76485.1 - 0.12 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CDO76485.1 - 0.13 11.9 0.0 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 CRAL_TRIO PF00650.15 CDO76486.1 - 1.6e-40 138.1 0.0 2.1e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CDO76486.1 - 4.9e-07 29.7 0.0 7.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CDO76486.1 - 0.00031 20.7 0.3 0.00072 19.6 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF3140 PF11338.3 CDO76488.1 - 6.8e-22 77.3 0.7 6.8e-22 77.3 0.5 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3140) O-FucT PF10250.4 CDO76489.1 - 0.00023 20.3 0.0 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Ribosomal_L28e PF01778.12 CDO76490.1 - 1.4e-30 106.0 0.0 1.8e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DAP PF15228.1 CDO76491.1 - 0.014 16.1 1.7 0.014 16.1 1.2 2.3 1 1 1 2 2 2 0 Death-associated protein HpaP PF09483.5 CDO76491.1 - 0.5 10.2 5.2 0.61 10.0 3.6 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) FMN_bind_2 PF04299.7 CDO76492.1 - 5.9e-53 178.8 0.0 7.1e-53 178.5 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain zf-CCHC PF00098.18 CDO76493.1 - 0.0067 16.2 1.4 0.0067 16.2 1.0 1.7 2 0 0 2 2 2 1 Zinc knuckle rve PF00665.21 CDO76494.1 - 2.4e-14 53.4 0.0 4.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CDO76494.1 - 9.7e-08 31.5 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CDO76494.1 - 0.0089 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain OpcA PF07239.6 CDO76494.1 - 0.2 10.5 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein OpcA Asp PF00026.18 CDO76496.1 - 1.4e-61 208.4 0.3 1.2e-46 159.4 1.4 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO76496.1 - 0.00018 21.4 4.8 0.00045 20.2 2.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO76496.1 - 0.017 15.5 0.1 0.052 14.0 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Glyco_hydro_15 PF00723.16 CDO76497.1 - 9.2e-51 172.7 0.0 1.1e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Dynactin_p62 PF05502.8 CDO76498.1 - 9.9e-63 212.5 0.1 4.9e-36 124.5 0.0 2.0 1 1 0 2 2 2 2 Dynactin p62 family UPF0547 PF10571.4 CDO76498.1 - 1.5 8.5 7.2 6.1 6.6 0.2 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Phosphodiest PF01663.17 CDO76499.1 - 4.6e-49 167.6 1.5 4.8e-40 138.0 0.4 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase PBP1_TM PF14812.1 CDO76499.1 - 0.0016 18.6 0.4 0.0029 17.8 0.3 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Asp PF00026.18 CDO76500.1 - 8e-26 91.0 0.1 6.2e-19 68.3 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CDO76500.1 - 0.00083 19.8 0.3 0.013 15.9 0.1 2.9 2 1 0 2 2 2 1 Aspartyl protease PepSY_TM PF03929.11 CDO76500.1 - 0.041 14.2 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix Herpes_gE PF02480.11 CDO76500.1 - 0.044 12.0 0.0 0.067 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2970 PF11174.3 CDO76500.1 - 0.11 12.1 1.4 0.24 10.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) TAXi_N PF14543.1 CDO76500.1 - 0.11 12.4 0.3 3.2 7.6 0.2 2.5 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Asp PF00026.18 CDO76501.1 - 2.3e-11 43.5 0.0 1.3e-10 41.0 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease IncA PF04156.9 CDO76501.1 - 0.11 12.0 0.9 0.16 11.5 0.6 1.2 1 0 0 1 1 1 0 IncA protein CD34_antigen PF06365.7 CDO76501.1 - 0.23 11.1 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Ribosomal_S10 PF00338.17 CDO76502.1 - 1.5e-31 108.0 0.5 1.8e-31 107.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF572 PF04502.8 CDO76503.1 - 1.8e-59 201.6 0.0 2.4e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) AAA_11 PF13086.1 CDO76503.1 - 0.09 12.3 0.3 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 AAA domain DUF1675 PF07897.6 CDO76503.1 - 0.16 11.8 3.1 0.26 11.1 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) cobW PF02492.14 CDO76504.1 - 1.2e-23 83.4 0.6 3.3e-22 78.7 0.4 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DnaJ PF00226.26 CDO76504.1 - 2.4e-18 65.6 0.1 3.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain MobB PF03205.9 CDO76504.1 - 0.0077 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Fungal_trans PF04082.13 CDO76505.1 - 9.5e-18 64.0 0.0 1.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNARE_assoc PF09335.6 CDO76506.1 - 9.6e-12 45.1 4.8 9.6e-12 45.1 3.3 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein Colicin PF01024.14 CDO76506.1 - 0.16 11.5 0.4 0.3 10.6 0.2 1.3 1 0 0 1 1 1 0 Colicin pore forming domain E1-E2_ATPase PF00122.15 CDO76506.1 - 0.17 10.9 3.8 4.4 6.2 0.7 2.2 2 0 0 2 2 2 0 E1-E2 ATPase ARID PF01388.16 CDO76507.1 - 1.8e-09 37.3 0.2 1.3e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain CorA PF01544.13 CDO76507.1 - 0.099 11.6 0.3 0.26 10.2 0.2 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Adaptin_N PF01602.15 CDO76508.1 - 7.3e-118 394.1 0.2 2.2e-117 392.5 0.2 1.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CDO76508.1 - 1.8e-11 44.1 7.2 5.3e-05 23.4 0.0 4.4 5 0 0 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 CDO76508.1 - 3.4e-05 24.1 0.8 0.67 10.5 0.0 4.9 4 1 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.2 CDO76508.1 - 0.0002 21.2 4.4 0.21 11.4 0.1 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CDO76508.1 - 0.0009 19.1 11.1 0.7 10.1 0.0 6.8 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.18 CDO76508.1 - 0.27 11.1 4.1 36 4.3 0.1 4.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Frag1 PF10277.4 CDO76509.1 - 1.1e-25 90.3 8.5 6.3e-25 87.9 1.0 2.6 1 1 1 2 2 2 2 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 CDO76509.1 - 0.0002 21.4 0.0 0.00044 20.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Amino_oxidase PF01593.19 CDO76511.1 - 5.6e-54 183.9 2.2 6.8e-28 97.9 0.2 3.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CDO76511.1 - 2.1e-10 40.4 0.1 6.9e-10 38.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO76511.1 - 4.8e-06 25.7 0.3 0.0014 17.5 0.0 2.9 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CDO76511.1 - 0.00013 22.0 0.1 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO76511.1 - 0.00018 21.8 1.4 0.013 15.8 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CDO76511.1 - 0.00026 20.1 1.7 0.00031 19.9 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 CDO76511.1 - 0.00053 18.9 0.1 0.0011 17.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 CDO76511.1 - 0.0032 16.6 2.5 0.0034 16.5 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CDO76511.1 - 0.0033 17.0 0.0 0.0088 15.6 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 CDO76511.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 CDO76511.1 - 0.024 13.5 0.9 0.55 9.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CDO76511.1 - 0.055 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_2 PF02230.11 CDO76512.1 - 6.8e-10 38.7 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CDO76512.1 - 0.00088 19.0 0.0 0.0019 18.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO76512.1 - 0.0032 17.3 0.0 0.0076 16.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO76513.1 - 6.4e-14 52.3 0.4 1.3e-13 51.3 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO76513.1 - 2.6e-08 33.7 0.0 4.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO76513.1 - 0.00034 20.3 0.1 0.00095 18.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family HSP20 PF00011.16 CDO76514.1 - 1.2e-24 86.1 0.1 1.5e-24 85.7 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family VLPT PF07122.6 CDO76514.1 - 0.0077 15.8 0.1 0.028 14.0 0.0 1.9 2 0 0 2 2 2 1 Variable length PCR target protein (VLPT) CS PF04969.11 CDO76514.1 - 0.025 15.1 0.1 0.076 13.5 0.1 1.7 1 1 1 2 2 2 0 CS domain BON PF04972.12 CDO76514.1 - 0.086 12.6 0.1 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 BON domain RNase_T PF00929.19 CDO76515.1 - 1.2e-18 67.9 0.0 1.8e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Alpha-amylase PF00128.19 CDO76516.1 - 5.4e-66 223.1 0.6 6.8e-66 222.8 0.4 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 CDO76516.1 - 1.3e-17 63.6 0.2 3e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.1 CDO76516.1 - 0.0049 15.8 0.0 0.0091 14.9 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Aminotran_5 PF00266.14 CDO76516.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V RicinB_lectin_2 PF14200.1 CDO76517.1 - 5.6e-19 68.4 4.0 2.7e-16 59.8 2.2 3.0 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 CDO76517.1 - 1.4e-06 28.3 0.4 0.003 17.5 0.0 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain WD40 PF00400.27 CDO76518.1 - 4.6e-30 102.3 25.3 1.4e-09 37.4 0.2 10.6 10 1 2 12 12 12 8 WD domain, G-beta repeat PD40 PF07676.7 CDO76518.1 - 0.069 12.8 1.6 18 5.1 0.0 3.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat NACHT PF05729.7 CDO76519.1 - 8.1e-07 28.8 0.2 0.00014 21.5 0.1 2.5 1 1 0 1 1 1 1 NACHT domain Not1 PF04054.10 CDO76521.1 - 2.6e-118 395.2 0.0 5.3e-118 394.1 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CDO76521.1 - 9e-53 177.9 0.1 2.4e-52 176.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) FdhE PF04216.7 CDO76521.1 - 0.28 10.8 1.6 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Peptidase_S9 PF00326.16 CDO76522.1 - 2.1e-06 27.1 0.0 3.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CDO76522.1 - 3.7e-05 23.2 0.0 0.0042 16.5 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase BcsB PF03170.8 CDO76522.1 - 0.00076 17.6 0.1 0.0012 16.9 0.1 1.2 1 0 0 1 1 1 1 Bacterial cellulose synthase subunit MFS_1 PF07690.11 CDO76524.1 - 6.8e-26 90.8 39.2 2.6e-23 82.3 16.3 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_63 PF03200.11 CDO76526.1 - 2.4e-161 538.3 0.0 7.3e-92 308.5 0.0 2.0 1 1 1 2 2 2 2 Mannosyl oligosaccharide glucosidase NYN PF01936.13 CDO76527.1 - 9.2e-28 97.3 0.0 1.6e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 NYN domain Sulfate_transp PF00916.15 CDO76528.1 - 1.1e-76 257.4 1.8 1.1e-76 257.4 1.3 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CDO76528.1 - 2.6e-31 107.1 4.5 2.6e-31 107.1 3.1 3.1 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CDO76528.1 - 1.5e-12 47.0 0.0 2.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CDO76528.1 - 0.015 15.3 0.0 0.051 13.6 0.0 1.9 1 0 0 1 1 1 0 STAS domain Sulfate_transp PF00916.15 CDO76529.1 - 6.9e-78 261.4 3.4 1.4e-77 260.5 2.4 1.5 1 0 0 1 1 1 1 Sulfate transporter family Transcrip_reg PF01709.15 CDO76529.1 - 6e-38 130.2 3.4 2e-18 66.3 0.7 2.2 1 1 1 2 2 2 2 Transcriptional regulator Sulfate_tra_GLY PF13792.1 CDO76529.1 - 2.9e-30 103.7 5.3 2.9e-30 103.7 3.7 3.3 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CDO76529.1 - 5.5e-12 45.1 0.0 1.2e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CDO76529.1 - 0.0075 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 STAS domain WD40 PF00400.27 CDO76530.1 - 2.1e-36 122.4 22.8 4.4e-13 48.5 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat NYN PF01936.13 CDO76531.1 - 7.5e-20 71.7 0.0 1.2e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 NYN domain DDE_Tnp_1_4 PF13701.1 CDO76531.1 - 0.11 10.6 0.0 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 PIN_4 PF13638.1 CDO76532.1 - 1.8e-07 31.3 0.0 2.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 PIN domain PhdYeFM_antitox PF02604.14 CDO76532.1 - 0.087 12.4 0.4 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Sugar_tr PF00083.19 CDO76533.1 - 5.2e-123 410.9 27.1 6e-123 410.7 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO76533.1 - 6.6e-22 77.6 43.8 2.2e-16 59.5 9.9 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily LMF1 PF06762.9 CDO76533.1 - 0.066 12.0 0.3 0.1 11.4 0.2 1.3 1 0 0 1 1 1 0 Lipase maturation factor Transposase_21 PF02992.9 CDO76536.1 - 2.6e-16 59.3 0.0 5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 RNase_H PF00075.19 CDO76537.1 - 5.3e-20 72.0 0.0 1.4e-19 70.7 0.0 1.8 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 CDO76537.1 - 9.9e-20 70.8 0.0 6.8e-19 68.0 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlxA PF14282.1 CDO76537.1 - 0.0036 17.2 0.4 0.0078 16.1 0.2 1.5 1 0 0 1 1 1 1 FlxA-like protein HTH_Tnp_Tc3_2 PF01498.13 CDO76537.1 - 0.063 13.3 0.0 0.48 10.5 0.0 2.5 3 0 0 3 3 3 0 Transposase Abhydrolase_3 PF07859.8 CDO76538.1 - 1.6e-29 103.0 0.0 3.9e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CDO76538.1 - 0.013 14.1 0.0 0.034 12.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) GrpE PF01025.14 CDO76538.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 GrpE Allantoicase PF03561.10 CDO76539.1 - 3.7e-89 295.9 0.0 1.4e-43 147.9 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 CDO76539.1 - 2.5e-43 147.2 0.0 3.2e-42 143.6 0.0 2.1 1 1 1 2 2 2 1 Ureidoglycolate hydrolase F5_F8_type_C PF00754.20 CDO76539.1 - 0.00015 21.5 0.0 0.0047 16.7 0.0 2.5 2 0 0 2 2 2 1 F5/8 type C domain BPL_N PF09825.4 CDO76540.1 - 2.5e-33 115.3 0.0 1.4e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 CDO76540.1 - 3.9e-19 68.9 0.0 6.8e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SUZ PF12752.2 CDO76541.1 - 6e-13 49.1 2.5 6e-13 49.1 1.7 2.4 3 0 0 3 3 3 1 SUZ domain FA_desaturase PF00487.19 CDO76541.1 - 2.8 7.3 5.4 4.4 6.6 3.8 1.2 1 0 0 1 1 1 0 Fatty acid desaturase GFO_IDH_MocA PF01408.17 CDO76542.1 - 1.1e-22 80.7 0.8 2.2e-22 79.8 0.5 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CDO76542.1 - 1.4e-05 24.8 0.0 0.00051 19.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 CDO76542.1 - 0.017 15.5 0.1 0.049 14.0 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 CDO76542.1 - 0.046 12.6 1.2 0.063 12.2 0.8 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Sugar_tr PF00083.19 CDO76544.1 - 8.4e-93 311.3 24.1 1.2e-70 238.3 7.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CDO76544.1 - 1.3e-17 63.6 38.0 9.7e-08 31.0 3.1 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF1228 PF06779.9 CDO76544.1 - 0.00064 19.7 3.6 0.088 12.8 0.2 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) zf-CCCH PF00642.19 CDO76545.1 - 0.012 15.2 11.5 0.074 12.7 2.5 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rho_GDI PF02115.12 CDO76546.1 - 6.7e-47 159.4 0.0 8.2e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.10 CDO76546.1 - 0.023 14.9 0.0 0.045 14.0 0.0 1.4 1 1 0 1 1 1 0 ML domain PBP_dimer PF03717.10 CDO76546.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.4 1 1 1 2 2 2 0 Penicillin-binding Protein dimerisation domain RIX1 PF08167.7 CDO76547.1 - 1.1e-07 31.7 0.3 1.1e-07 31.7 0.2 1.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Usg PF06233.7 CDO76547.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Usg-like family RNA_pol_Rpb1_5 PF04998.12 CDO76550.1 - 4.2e-82 275.5 0.0 7.1e-82 274.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CDO76550.1 - 4.3e-59 199.1 0.0 8e-59 198.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CDO76550.1 - 9.9e-38 129.3 0.0 2.2e-37 128.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 CDO76550.1 - 2e-09 37.2 2.8 0.0014 17.9 0.1 3.8 4 1 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 CDO76550.1 - 3.3e-05 23.5 0.0 0.0001 22.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RRM_1 PF00076.17 CDO76551.1 - 3.2e-19 68.3 0.1 3.2e-19 68.3 0.1 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO76551.1 - 1.4e-15 57.0 0.0 2.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO76551.1 - 2e-10 40.3 0.0 3.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CDO76551.1 - 0.015 15.1 0.3 0.039 13.7 0.2 1.7 1 1 0 1 1 1 0 RNA binding motif PBP PF01161.15 CDO76552.1 - 5.4e-17 62.0 0.0 8.3e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DEAD PF00270.24 CDO76554.1 - 7e-42 142.7 0.3 2e-41 141.3 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO76554.1 - 3.5e-28 97.2 0.1 7.3e-28 96.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CDO76554.1 - 0.0093 16.1 0.1 0.03 14.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CDO76554.1 - 0.0094 15.8 0.0 0.053 13.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CDO76554.1 - 0.013 15.2 0.2 0.034 13.8 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain SecA_DEAD PF07517.9 CDO76554.1 - 0.037 13.3 0.1 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 SecA DEAD-like domain tRNA-synt_1b PF00579.20 CDO76554.1 - 0.067 12.2 0.0 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DUF3449 PF11931.3 CDO76555.1 - 4.4e-71 238.4 0.2 4.4e-71 238.4 0.2 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3449) zf-met PF12874.2 CDO76555.1 - 1.2e-07 31.6 6.9 2e-07 30.9 1.0 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CDO76555.1 - 5.2e-07 29.6 0.8 5.2e-07 29.6 0.6 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.3 CDO76555.1 - 0.00012 21.4 0.0 0.00029 20.3 0.0 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.2 CDO76555.1 - 0.0037 17.3 5.5 0.064 13.3 0.6 2.9 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 CDO76555.1 - 0.0042 16.7 3.4 0.12 12.1 0.0 2.8 2 0 0 2 2 2 1 DBF zinc finger DUF951 PF06107.6 CDO76555.1 - 0.055 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) CTK3 PF12243.3 CDO76555.1 - 0.092 12.3 0.2 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF3892 PF13031.1 CDO76555.1 - 1.5 9.3 6.4 7.4 7.0 0.5 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3892) Syja_N PF02383.13 CDO76556.1 - 3.7e-66 223.0 0.0 5e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CDO76556.1 - 9.5e-25 87.9 0.1 1.9e-24 86.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family F-box-like PF12937.2 CDO76557.1 - 0.063 13.0 0.2 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 F-box-like adh_short PF00106.20 CDO76558.1 - 2.1e-31 109.0 0.3 4.8e-31 107.9 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO76558.1 - 1.1e-13 51.2 0.7 1.7e-12 47.3 0.5 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CDO76558.1 - 4.9e-09 36.3 0.0 7.1e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CDO76558.1 - 0.001 19.1 0.0 0.0032 17.5 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CDO76558.1 - 0.029 13.7 0.1 0.06 12.7 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2316 PF10078.4 CDO76558.1 - 0.055 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF883 PF05957.8 CDO76559.1 - 0.13 12.6 0.1 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TFR_dimer PF04253.10 CDO76560.1 - 9.6e-14 51.0 0.1 4e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 CDO76560.1 - 2.9e-12 46.6 0.0 6.9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CDO76560.1 - 1.8e-05 24.3 0.1 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 PA domain Alpha-amylase_C PF02806.13 CDO76561.1 - 2.8e-22 78.6 0.2 7.8e-21 74.0 0.1 2.9 2 1 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CDO76561.1 - 4.5e-18 65.6 0.6 4.3e-14 52.6 0.0 2.7 2 1 1 3 3 3 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 CDO76561.1 - 3.3e-16 59.1 0.1 7.1e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Spermine_synth PF01564.12 CDO76562.1 - 1.6e-07 30.5 0.0 2.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase BTB PF00651.26 CDO76563.1 - 0.00031 20.7 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4337 PF14235.1 CDO76564.1 - 4.8 6.9 6.4 8.2 6.2 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SAP PF02037.22 CDO76566.1 - 4.9e-08 32.2 0.7 1.1e-07 31.1 0.3 1.7 2 0 0 2 2 2 1 SAP domain Spherulin4 PF12138.3 CDO76567.1 - 6.4e-43 147.0 0.0 7.4e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 ubiquitin PF00240.18 CDO76568.1 - 1e-08 34.4 0.0 1.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CDO76568.1 - 0.044 13.4 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CDO76568.1 - 0.065 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF4605 PF15378.1 CDO76568.1 - 0.074 12.7 0.6 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) Rad60-SLD_2 PF13881.1 CDO76568.1 - 0.16 11.8 0.0 0.4 10.5 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 CDO76568.1 - 0.83 9.3 0.0 0.83 9.3 0.0 2.9 3 0 0 3 3 3 0 Telomere stability and silencing cNMP_binding PF00027.24 CDO76569.1 - 5.5e-38 128.6 0.0 1e-17 63.7 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CDO76569.1 - 7.8e-07 28.4 0.5 2.9e-06 26.6 0.1 2.1 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit Glyco_hydro_61 PF03443.9 CDO76571.1 - 2.5e-44 151.6 0.0 3.4e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 CDO76572.1 - 3.4e-35 121.3 13.2 2.5e-33 115.2 10.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.1 CDO76572.1 - 0.027 14.5 0.0 0.086 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2109 PF09882.4 CDO76572.1 - 0.16 11.9 2.5 0.52 10.2 1.8 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) Dimer_Tnp_hAT PF05699.9 CDO76573.1 - 3.9e-14 52.0 0.0 1.1e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.10 CDO76574.1 - 0.026 13.9 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) tRNA-synt_1c PF00749.16 CDO76574.1 - 0.16 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain SMC_N PF02463.14 CDO76576.1 - 1.1e-66 224.2 0.0 3.4e-66 222.6 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CDO76576.1 - 1e-20 73.9 0.3 1e-19 70.6 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CDO76576.1 - 6.8e-16 59.1 8.6 6.8e-16 59.1 5.9 6.4 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.1 CDO76576.1 - 3.7e-14 53.3 1.8 3.4e-06 27.2 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 CDO76576.1 - 1.3e-05 24.4 0.0 1.3e-05 24.4 0.0 2.9 2 2 1 3 3 2 1 AAA ATPase domain AAA_13 PF13166.1 CDO76576.1 - 1.9e-05 23.3 36.0 1.9e-05 23.3 25.0 5.9 4 1 3 7 7 7 3 AAA domain Reo_sigmaC PF04582.7 CDO76576.1 - 2.9e-05 23.3 23.8 0.00095 18.4 2.1 4.9 3 2 2 5 5 5 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 CDO76576.1 - 3.7e-05 23.1 0.0 0.00011 21.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.2 CDO76576.1 - 0.0028 17.0 14.2 0.0028 17.0 9.8 6.7 4 2 3 8 8 8 2 Mechanosensitive ion channel porin domain ABC_tran PF00005.22 CDO76576.1 - 0.4 10.9 34.1 2.8 8.2 1.9 6.9 2 2 1 3 3 3 0 ABC transporter WEMBL PF05701.6 CDO76576.1 - 1.2 7.4 100.1 0.019 13.4 28.8 3.0 2 1 0 2 2 2 0 Weak chloroplast movement under blue light Spc7 PF08317.6 CDO76576.1 - 2.5 6.6 91.2 0.03 13.0 9.5 7.0 3 2 5 8 8 8 0 Spc7 kinetochore protein IncA PF04156.9 CDO76576.1 - 2.8 7.4 94.3 0.01 15.4 17.9 6.5 3 2 3 6 6 6 0 IncA protein Filament PF00038.16 CDO76576.1 - 8.9 5.6 91.6 0.62 9.4 5.3 7.3 3 2 1 4 4 4 0 Intermediate filament protein Macoilin PF09726.4 CDO76577.1 - 4.6 5.4 15.0 5.8 5.0 10.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Wzy_C PF04932.10 CDO76578.1 - 0.0075 16.0 0.6 0.016 15.0 0.4 1.5 1 0 0 1 1 1 1 O-Antigen ligase HEAT PF02985.17 CDO76578.1 - 0.073 13.1 0.1 0.41 10.8 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat NfeD PF01957.13 CDO76578.1 - 0.14 12.3 4.7 0.27 11.3 2.0 2.3 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding MFS_1 PF07690.11 CDO76579.1 - 1.3e-39 135.9 45.7 4.4e-39 134.1 31.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Trm112p PF03966.11 CDO76580.1 - 2.8e-22 78.8 0.0 3.5e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-NADH-PPase PF09297.6 CDO76580.1 - 0.0088 15.5 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zf-RING_4 PF14570.1 CDO76580.1 - 0.089 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PhnA_Zn_Ribbon PF08274.7 CDO76580.1 - 0.12 12.1 0.2 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Methyltransf_30 PF05430.6 CDO76580.1 - 0.14 11.8 0.0 15 5.2 0.0 2.1 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase AhpC-TSA PF00578.16 CDO76581.1 - 1.8e-40 137.4 0.0 2.6e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CDO76581.1 - 3.1e-14 52.7 0.0 4.3e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CDO76581.1 - 9.8e-14 50.7 0.0 1.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin F-box-like PF12937.2 CDO76582.1 - 2.7e-05 23.8 0.1 8.2e-05 22.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO76582.1 - 0.00013 21.5 0.2 0.00035 20.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain DUF3306 PF11748.3 CDO76582.1 - 0.077 13.6 5.8 0.13 12.9 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) RNase_PH PF01138.16 CDO76584.1 - 1e-18 67.8 0.0 1.6e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CDO76584.1 - 4.4e-07 29.7 0.0 7.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Peptidase_M48 PF01435.13 CDO76585.1 - 1.3e-18 67.3 0.1 7.1e-18 65.0 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M48 DEAD PF00270.24 CDO76586.1 - 4.3e-08 32.8 0.0 7.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AhpC-TSA_2 PF13911.1 CDO76586.1 - 0.0057 16.5 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Amino_oxidase PF01593.19 CDO76587.1 - 3.4e-49 168.1 1.6 6.7e-28 97.9 0.2 3.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CDO76587.1 - 1.8e-10 40.7 0.1 6.2e-10 38.9 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO76587.1 - 2.4e-05 23.3 0.2 0.0013 17.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CDO76587.1 - 0.00012 22.4 1.2 0.012 15.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDO76587.1 - 0.00013 22.0 0.2 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CDO76587.1 - 0.00028 20.0 1.9 0.00028 20.0 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 CDO76587.1 - 0.00053 18.9 0.1 0.001 17.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 CDO76587.1 - 0.0031 16.6 0.9 0.0031 16.6 0.7 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CDO76587.1 - 0.0045 16.5 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 CDO76587.1 - 0.0098 16.0 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 CDO76587.1 - 0.022 13.6 0.9 0.54 9.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CDO76587.1 - 0.052 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PIG-P PF08510.7 CDO76588.1 - 0.24 11.0 2.4 0.61 9.7 1.7 1.6 1 0 0 1 1 1 0 PIG-P Epimerase PF01370.16 CDO76590.1 - 0.0036 16.7 0.2 0.76 9.1 0.0 2.5 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family GMC_oxred_N PF00732.14 CDO76592.1 - 3e-53 180.8 0.0 5.4e-52 176.7 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO76592.1 - 3e-38 131.3 0.0 4.9e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 CDO76592.1 - 4.1e-05 23.5 0.0 9.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO76592.1 - 0.00035 19.5 0.5 0.00079 18.4 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CDO76592.1 - 0.00038 19.5 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CDO76592.1 - 0.00053 18.9 0.1 0.011 14.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 CDO76592.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 CDO76592.1 - 0.06 13.2 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyridox_oxidase PF01243.15 CDO76592.1 - 0.083 12.9 0.0 17 5.4 0.0 2.6 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Trp_halogenase PF04820.9 CDO76592.1 - 0.25 9.9 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 CDO76592.1 - 0.29 9.5 0.0 0.5 8.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_10 PF13460.1 CDO76593.1 - 2.9e-14 53.5 0.0 5.4e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CDO76593.1 - 1.1e-08 34.6 0.0 1.5e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 CDO76593.1 - 0.02 13.6 0.0 0.044 12.4 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CDO76593.1 - 0.025 13.9 0.1 0.65 9.3 0.0 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family POC1 PF10450.4 CDO76593.1 - 0.088 11.5 0.0 0.21 10.2 0.0 1.5 2 0 0 2 2 2 0 POC1 chaperone 2-Hacid_dh PF00389.25 CDO76593.1 - 0.11 12.0 0.2 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain LTV PF04180.9 CDO76594.1 - 0.86 9.0 10.4 1.2 8.5 7.2 1.2 1 0 0 1 1 1 0 Low temperature viability protein BUD22 PF09073.5 CDO76594.1 - 1 8.3 8.7 1.2 8.1 6.0 1.0 1 0 0 1 1 1 0 BUD22 Glyco_hydro_3 PF00933.16 CDO76595.1 - 4.9e-83 278.5 0.0 6.8e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CDO76595.1 - 3.4e-65 219.7 0.4 9.7e-65 218.2 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CDO76595.1 - 1.5e-18 66.4 0.1 3.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain p450 PF00067.17 CDO76596.1 - 4.1e-70 236.5 0.0 2.1e-69 234.2 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 IncA PF04156.9 CDO76597.1 - 0.11 12.0 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 IncA protein RseC_MucC PF04246.7 CDO76597.1 - 2.7 7.5 6.7 0.53 9.8 1.3 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SWIB PF02201.13 CDO76599.1 - 2.2e-16 59.2 0.0 4.4e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain p450 PF00067.17 CDO76601.1 - 5.8e-58 196.5 0.0 2.5e-38 131.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 RPW8 PF05659.6 CDO76601.1 - 0.12 11.9 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BAR PF03114.13 CDO76602.1 - 1.8e-33 115.9 8.6 2.6e-33 115.4 6.0 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 CDO76602.1 - 7.6e-16 57.4 0.0 1.5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CDO76602.1 - 2.6e-15 55.5 0.0 4.9e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CDO76602.1 - 2.7e-13 49.1 0.0 5.7e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Filament PF00038.16 CDO76602.1 - 0.0042 16.6 11.4 0.0074 15.7 7.9 1.3 1 0 0 1 1 1 1 Intermediate filament protein GAS PF13851.1 CDO76602.1 - 0.03 13.5 10.5 0.055 12.6 7.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 CDO76602.1 - 0.12 12.0 19.3 0.023 14.4 10.1 2.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF883 PF05957.8 CDO76602.1 - 0.18 12.2 2.9 0.84 10.0 2.0 2.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MscS_TM PF12794.2 CDO76602.1 - 0.65 8.5 5.8 1 7.8 4.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 APG6 PF04111.7 CDO76602.1 - 5.6 5.9 13.1 10 5.0 9.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CDO76602.1 - 9.3 5.8 14.7 0.29 10.7 5.8 1.7 2 0 0 2 2 2 0 IncA protein p450 PF00067.17 CDO76603.1 - 1.1e-14 53.8 0.0 1.2e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hap4_Hap_bind PF10297.4 CDO76605.1 - 1.5e-07 31.0 6.8 3.4e-07 29.8 4.7 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 CDO76605.1 - 0.003 17.4 22.4 0.048 13.6 15.5 2.4 1 1 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 CDO76605.1 - 0.0061 16.2 3.9 0.0061 16.2 2.7 1.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper bZIP_2 PF07716.10 CDO76605.1 - 0.049 13.4 18.7 0.45 10.3 3.4 2.7 2 0 0 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 CDO76605.1 - 0.074 13.4 7.2 0.15 12.3 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF572 PF04502.8 CDO76605.1 - 0.08 12.1 9.4 0.13 11.4 6.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Seadorna_VP6 PF07407.6 CDO76605.1 - 0.23 10.1 0.5 0.32 9.6 0.4 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF904 PF06005.7 CDO76605.1 - 0.56 10.5 10.9 1 9.7 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF87 PF01935.12 CDO76605.1 - 0.73 9.6 2.8 33 4.2 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 NYD-SP28_assoc PF14775.1 CDO76605.1 - 5.8 6.6 7.2 1 9.1 1.3 2.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF4337 PF14235.1 CDO76605.1 - 7.4 6.3 10.1 12 5.6 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) IncA PF04156.9 CDO76605.1 - 7.8 6.0 10.3 13 5.3 7.2 1.3 1 0 0 1 1 1 0 IncA protein PPR_2 PF13041.1 CDO76606.1 - 1e-27 95.8 1.0 5.2e-07 29.5 0.0 6.8 5 1 2 7 7 7 5 PPR repeat family PPR_1 PF12854.2 CDO76606.1 - 2.3e-16 58.9 0.4 7.9e-05 22.0 0.0 5.3 5 0 0 5 5 5 3 PPR repeat PPR PF01535.15 CDO76606.1 - 2.4e-16 58.4 3.7 2.3e-05 24.0 0.0 6.6 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.1 CDO76606.1 - 1.8e-15 55.8 29.2 0.00028 20.9 0.0 9.0 11 0 0 11 11 11 5 Pentatricopeptide repeat domain TPR_14 PF13428.1 CDO76606.1 - 5.1 8.0 31.6 3.1 8.6 0.1 8.7 8 2 2 10 10 10 0 Tetratricopeptide repeat APH PF01636.18 CDO76607.1 - 4.2e-10 39.7 0.2 7.4e-10 38.9 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CDO76607.1 - 0.0037 16.4 0.0 0.0045 16.1 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.9 CDO76607.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CDO76607.1 - 0.17 11.4 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Shisa PF13908.1 CDO76609.1 - 0.0049 17.0 2.0 0.0049 17.0 1.4 1.9 1 1 0 2 2 2 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 CDO76609.1 - 0.053 11.7 0.1 0.14 10.4 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CDO76609.1 - 0.11 12.8 0.1 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 CDO76609.1 - 0.16 11.6 0.3 0.39 10.3 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain LRR19-TM PF15176.1 CDO76610.1 - 0.0026 17.4 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain Herpes_gE PF02480.11 CDO76610.1 - 0.09 11.0 0.1 0.14 10.3 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E AMP-binding PF00501.23 CDO76611.1 - 1.6e-31 109.1 0.0 5.9e-31 107.2 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme EamA PF00892.15 CDO76612.1 - 1.7e-08 34.5 1.6 1.7e-08 34.5 1.1 2.8 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 CDO76612.1 - 2.4e-05 23.3 10.5 0.0002 20.3 5.0 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 CDO76612.1 - 8.4e-05 22.7 0.8 8.4e-05 22.7 0.5 3.8 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 CDO76612.1 - 0.00074 18.5 8.7 0.00074 18.5 6.0 1.5 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 CDO76612.1 - 0.00083 19.0 2.9 0.00083 19.0 2.0 2.8 3 0 0 3 3 3 1 Triose-phosphate Transporter family DUF986 PF06173.7 CDO76612.1 - 0.08 12.7 0.5 5.4 6.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF986) SLX9 PF15341.1 CDO76613.1 - 1.1e-21 77.4 2.5 2e-21 76.6 1.8 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 GBP_C PF02841.9 CDO76613.1 - 0.06 12.5 2.1 0.084 12.0 1.4 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain TPR_7 PF13176.1 CDO76613.1 - 0.13 12.1 0.1 9.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF904 PF06005.7 CDO76614.1 - 0.0069 16.6 30.5 2.2 8.6 3.9 4.7 3 1 1 4 4 4 3 Protein of unknown function (DUF904) IncA PF04156.9 CDO76614.1 - 0.0081 15.7 16.0 0.0081 15.7 11.1 3.0 4 0 0 4 4 4 2 IncA protein DUF2265 PF10023.4 CDO76614.1 - 0.1 11.7 6.1 0.17 10.9 4.3 1.4 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Tup_N PF08581.5 CDO76614.1 - 0.15 12.3 12.4 0.058 13.5 3.9 3.3 3 1 0 3 3 3 0 Tup N-terminal COG5 PF10392.4 CDO76614.1 - 0.42 10.5 10.9 0.67 9.9 2.6 2.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 APG6 PF04111.7 CDO76614.1 - 0.67 8.9 22.7 2.1 7.3 0.1 2.7 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 CDO76614.1 - 1.2 9.4 20.8 3.2 8.1 0.2 4.7 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Cep57_CLD_2 PF14197.1 CDO76614.1 - 1.2 9.0 21.0 0.27 11.2 5.9 3.7 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF948 PF06103.6 CDO76614.1 - 1.8 8.4 9.5 0.42 10.5 1.8 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF724 PF05266.9 CDO76614.1 - 5.2 6.6 15.0 0.8 9.2 7.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) AAA_25 PF13481.1 CDO76615.1 - 0.0044 16.4 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDO76615.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Rad51 PF08423.6 CDO76615.1 - 0.044 12.6 0.0 0.11 11.4 0.0 1.6 1 1 0 1 1 1 0 Rad51 AMP-binding PF00501.23 CDO76616.1 - 2.9e-16 58.9 1.1 1.6e-15 56.4 0.8 1.9 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 CDO76616.1 - 0.0028 16.2 0.0 0.0046 15.5 0.0 1.2 1 0 0 1 1 1 1 GH3 auxin-responsive promoter LRR_8 PF13855.1 CDO76617.1 - 0.0024 17.5 0.2 3.1 7.6 0.0 3.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 CDO76617.1 - 0.02 14.5 3.2 42 3.9 0.1 5.2 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CDO76617.1 - 0.034 14.2 2.1 49 4.4 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich repeat DUF4591 PF15261.1 CDO76617.1 - 0.16 12.2 0.0 30 4.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4591) PRANC PF09372.5 CDO76617.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 PRANC domain Nefa_Nip30_N PF10187.4 CDO76619.1 - 2e-14 53.5 0.5 2e-14 53.5 0.4 2.2 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Es2 PF09751.4 CDO76620.1 - 8.1e-83 279.1 0.2 1e-82 278.7 0.1 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 SUZ-C PF12901.2 CDO76620.1 - 0.032 13.8 1.9 0.095 12.3 1.3 1.7 1 0 0 1 1 1 0 SUZ-C motif NUDE_C PF04880.8 CDO76621.1 - 0.00036 20.9 23.3 0.00036 20.9 16.1 5.9 3 3 2 5 5 4 1 NUDE protein, C-terminal conserved region AAA_27 PF13514.1 CDO76621.1 - 0.0016 16.2 22.3 0.0023 15.7 15.4 1.1 1 0 0 1 1 1 1 AAA domain ERM PF00769.14 CDO76621.1 - 0.028 13.9 30.3 0.011 15.2 11.6 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family GAS PF13851.1 CDO76621.1 - 0.46 9.6 31.8 1.6 7.9 1.3 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 CDO76621.1 - 1.3 6.2 24.9 1.8 5.7 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SPATA24 PF15175.1 CDO76621.1 - 1.4 8.6 18.8 0.57 9.8 5.7 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 TPR_MLP1_2 PF07926.7 CDO76621.1 - 2 8.1 30.4 1.4 8.6 5.3 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 CDO76621.1 - 3.1 7.6 35.7 0.21 11.4 16.5 2.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 CDO76621.1 - 6.6 5.6 30.5 0.62 9.0 15.3 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Borrelia_P83 PF05262.6 CDO76621.1 - 6.8 4.8 14.9 9.6 4.3 10.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein COG2 PF06148.6 CDO76621.1 - 6.8 6.5 19.4 0.25 11.1 2.8 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.6 CDO76621.1 - 7.4 6.3 21.6 2.8 7.6 0.4 3.3 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF342 PF03961.8 CDO76621.1 - 9.4 4.5 21.5 2.2 6.5 6.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) EXOSC1 PF10447.4 CDO76622.1 - 5.3e-20 71.1 0.1 9.8e-20 70.3 0.1 1.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 2-oxoacid_dh PF00198.18 CDO76623.1 - 1.8e-83 279.3 0.0 2.3e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CDO76623.1 - 3.6e-19 68.1 0.5 9e-19 66.8 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CDO76623.1 - 9.3e-17 60.3 0.2 2.2e-16 59.1 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain ATG16 PF08614.6 CDO76625.1 - 0.7 9.6 37.8 4.1 7.1 13.5 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 CDO76625.1 - 0.82 9.4 33.4 1 9.0 2.4 4.2 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding adh_short PF00106.20 CDO76626.1 - 1.5e-18 67.3 0.0 1.9e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO76626.1 - 2e-08 34.1 0.0 7.3e-06 25.7 0.0 2.5 3 0 0 3 3 3 2 KR domain adh_short_C2 PF13561.1 CDO76626.1 - 3.6e-07 30.2 0.0 4.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CDO76626.1 - 0.0004 19.9 0.0 0.002 17.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 CDO76626.1 - 0.0019 17.2 0.1 0.0025 16.8 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 CDO76626.1 - 0.0096 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CDO76626.1 - 0.021 14.8 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF1776 PF08643.5 CDO76626.1 - 0.042 12.9 0.2 0.051 12.7 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.15 CDO76626.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CDO76626.1 - 0.08 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 CDO76627.1 - 1.6e-07 31.4 0.0 1.8e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO76627.1 - 0.0032 17.2 0.0 0.0038 17.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 CDO76627.1 - 0.011 14.9 0.4 0.013 14.6 0.3 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TPR_11 PF13414.1 CDO76628.1 - 2.1e-15 56.1 1.6 3.9e-06 26.4 0.0 3.2 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 CDO76628.1 - 3e-11 42.4 0.4 0.0012 18.4 0.1 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDO76628.1 - 5.7e-10 38.3 0.7 0.0032 17.2 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CDO76628.1 - 7e-05 22.3 0.0 0.29 11.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDO76628.1 - 0.00013 21.8 0.7 0.82 9.6 0.1 3.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDO76628.1 - 0.001 19.6 2.1 0.24 12.1 0.6 3.3 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDO76628.1 - 0.0064 17.0 8.1 0.36 11.5 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat BSP_II PF05432.6 CDO76628.1 - 0.0079 15.5 0.1 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) TPR_8 PF13181.1 CDO76628.1 - 0.021 14.6 0.1 8.6 6.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_S26 PF10502.4 CDO76629.1 - 8.9e-06 25.2 0.0 0.00024 20.6 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 CDO76629.1 - 5.1e-05 22.8 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase S24-like PAXNEB PF05625.6 CDO76630.1 - 2.2e-55 187.9 0.0 2.9e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein F-box-like PF12937.2 CDO76631.1 - 8.9e-06 25.3 0.5 2.9e-05 23.6 0.4 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 CDO76631.1 - 0.12 12.1 0.6 14 5.4 0.0 2.7 2 0 0 2 2 2 0 F-box domain AdoMet_MTase PF07757.8 CDO76632.1 - 7.8e-35 119.3 0.0 3.1e-16 59.4 0.0 2.2 1 1 1 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 CDO76632.1 - 0.0002 21.1 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO76632.1 - 0.02 14.4 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 CDO76632.1 - 0.025 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CDO76632.1 - 0.028 13.8 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 CDO76632.1 - 0.031 14.7 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CDO76632.1 - 0.036 14.6 0.0 0.068 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CDO76632.1 - 0.056 13.4 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 CDO76632.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.7 CDO76632.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.1 CDO76632.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CDO76632.1 - 0.16 12.4 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pil1 PF13805.1 CDO76633.1 - 2.8e-22 79.1 0.4 5.7e-22 78.1 0.3 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 DUF972 PF06156.8 CDO76633.1 - 0.07 13.4 4.1 0.16 12.3 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF607 PF04678.8 CDO76633.1 - 0.81 9.5 2.3 1.6 8.6 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 IncA PF04156.9 CDO76633.1 - 0.93 9.0 6.8 1.8 8.1 3.6 2.1 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 CDO76633.1 - 1.3 7.9 7.4 2.7 6.9 5.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CDO76633.1 - 7.4 6.1 9.8 4.4 6.8 4.7 2.2 1 1 1 2 2 2 0 Septum formation initiator IF4E PF01652.13 CDO76634.1 - 2e-49 167.3 0.0 2.7e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2888 PF11135.3 CDO76634.1 - 0.042 13.5 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2888) SMN PF06003.7 CDO76637.1 - 8.4e-09 34.9 12.0 2.6e-08 33.3 7.5 1.8 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 CDO76637.1 - 1.2e-06 28.3 0.0 2.5e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Tudor domain PWWP PF00855.12 CDO76637.1 - 0.003 17.7 4.7 0.015 15.5 3.3 2.2 1 1 0 1 1 1 1 PWWP domain Relaxase PF03432.9 CDO76637.1 - 0.0041 16.5 3.2 0.0079 15.6 2.2 1.4 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain Cas_Csy4 PF09618.5 CDO76637.1 - 0.12 12.1 2.5 0.23 11.2 1.7 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) OmpH PF03938.9 CDO76637.1 - 0.38 10.6 12.5 0.12 12.3 2.8 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RR_TM4-6 PF06459.7 CDO76637.1 - 0.58 9.9 12.5 0.21 11.4 4.5 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.5 CDO76637.1 - 0.93 7.8 6.0 1.2 7.4 4.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NARP1 PF12569.3 CDO76637.1 - 2.4 6.8 13.5 0.17 10.6 5.2 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RP-C_C PF11800.3 CDO76637.1 - 4.3 6.9 10.1 2.1 8.0 0.3 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region RIO1 PF01163.17 CDO76638.1 - 2.9e-48 163.7 0.0 5.1e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CDO76638.1 - 2e-33 114.2 0.1 3.6e-33 113.4 0.1 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 CDO76638.1 - 2.3e-11 43.8 0.1 7.2e-05 22.6 0.0 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CDO76638.1 - 1.1e-06 27.9 0.0 1.4e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_1 PF00583.19 CDO76639.1 - 4.6e-13 49.0 0.0 6.1e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDO76639.1 - 4e-07 30.0 0.1 5.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO76639.1 - 1.2e-05 24.9 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CDO76639.1 - 1.4e-05 25.2 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CDO76639.1 - 0.0008 19.3 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CDO76639.1 - 0.043 13.6 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CDO76639.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pex14_N PF04695.8 CDO76640.1 - 7.4e-26 90.8 2.0 7.4e-26 90.8 1.4 3.2 3 1 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 CDO76640.1 - 6.4e-05 22.6 3.1 0.0001 21.9 2.2 1.3 1 0 0 1 1 1 1 IncA protein IFT57 PF10498.4 CDO76640.1 - 0.00098 17.9 5.7 0.0031 16.3 3.9 1.6 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 CENP-Q PF13094.1 CDO76640.1 - 0.0097 15.9 2.8 0.0097 15.9 1.9 1.8 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit AAA_13 PF13166.1 CDO76640.1 - 0.01 14.3 7.0 0.013 13.9 4.9 1.1 1 0 0 1 1 1 0 AAA domain Prominin PF05478.6 CDO76640.1 - 0.011 13.3 1.5 0.015 12.9 1.0 1.1 1 0 0 1 1 1 0 Prominin Phage_GPO PF05929.6 CDO76640.1 - 0.026 13.7 2.5 0.041 13.1 1.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Laminin_II PF06009.7 CDO76640.1 - 0.026 14.2 10.1 0.049 13.3 7.0 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF1759 PF03564.10 CDO76640.1 - 0.033 13.9 2.7 0.042 13.6 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) DUF3584 PF12128.3 CDO76640.1 - 0.067 10.5 12.3 0.09 10.0 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.7 CDO76640.1 - 0.069 13.4 12.2 0.44 10.8 0.3 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF334 PF03904.8 CDO76640.1 - 0.14 11.4 3.4 0.19 10.9 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Flagellar_rod PF05149.7 CDO76640.1 - 0.19 10.8 9.4 0.22 10.6 6.0 1.5 1 1 0 1 1 1 0 Paraflagellar rod protein SecD-TM1 PF13721.1 CDO76640.1 - 0.2 11.9 1.9 0.34 11.1 0.0 2.2 2 1 1 3 3 2 0 SecD export protein N-terminal TM region NEP PF10167.4 CDO76640.1 - 0.22 11.2 3.8 0.39 10.4 2.3 1.6 2 0 0 2 2 1 0 Uncharacterised conserved protein Baculo_PEP_C PF04513.7 CDO76640.1 - 0.23 11.2 3.7 0.39 10.5 2.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ING PF12998.2 CDO76640.1 - 0.26 11.5 7.0 0.36 11.1 4.4 1.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding V_ATPase_I PF01496.14 CDO76640.1 - 0.28 8.9 4.4 0.38 8.5 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2317 PF10079.4 CDO76640.1 - 0.31 9.5 10.0 0.8 8.2 6.8 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF1409 PF07197.7 CDO76640.1 - 0.32 11.1 4.3 0.12 12.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) Fib_alpha PF08702.5 CDO76640.1 - 0.33 11.0 4.9 0.61 10.1 3.4 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 CDO76640.1 - 0.46 9.0 9.2 0.29 9.7 4.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein HAUS6_N PF14661.1 CDO76640.1 - 0.53 9.5 6.9 0.9 8.8 4.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Sas10_Utp3 PF04000.10 CDO76640.1 - 0.54 10.4 5.5 2.6 8.3 1.5 2.5 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Mitofilin PF09731.4 CDO76640.1 - 0.65 8.5 14.3 0.1 11.1 3.3 2.1 1 1 1 2 2 2 0 Mitochondrial inner membrane protein TPR_MLP1_2 PF07926.7 CDO76640.1 - 0.85 9.3 13.8 1.7 8.3 9.6 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ALMT PF11744.3 CDO76640.1 - 0.95 8.0 2.7 1.7 7.2 2.0 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter COG2 PF06148.6 CDO76640.1 - 1 9.2 12.1 0.86 9.4 1.3 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Med9 PF07544.8 CDO76640.1 - 1.9 8.3 11.6 2.6 7.8 2.8 2.9 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CDC37_N PF03234.9 CDO76640.1 - 2 8.6 9.4 3 8.1 6.5 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding YkuI_C PF10388.4 CDO76640.1 - 2.1 8.0 7.3 8.4 6.0 0.0 2.8 1 1 1 3 3 3 0 EAL-domain associated signalling protein domain DUF812 PF05667.6 CDO76640.1 - 2.2 6.7 11.4 3 6.2 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Mnd1 PF03962.10 CDO76640.1 - 2.5 7.7 10.4 4.4 6.9 7.2 1.4 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 CDO76640.1 - 2.6 6.9 13.1 3.9 6.4 9.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2664 PF10867.3 CDO76640.1 - 3.9 8.1 8.9 3.8 8.1 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) DUF4407 PF14362.1 CDO76640.1 - 5.5 5.8 10.8 12 4.7 7.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 CDO76640.1 - 9.5 6.6 9.9 38 4.6 6.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) GTP_EFTU PF00009.22 CDO76641.1 - 1.9e-59 200.2 1.1 2.9e-59 199.6 0.4 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CDO76641.1 - 2e-26 92.0 0.1 8.2e-26 90.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CDO76641.1 - 4.9e-16 58.5 2.9 4.9e-16 58.5 2.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CDO76641.1 - 7.9e-06 25.8 0.1 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CDO76641.1 - 0.00093 19.6 0.1 0.0016 18.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CDO76641.1 - 0.011 15.2 0.4 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CDO76641.1 - 0.027 13.9 0.7 0.055 12.9 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 CDO76641.1 - 0.064 12.6 2.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DisA_N PF02457.11 CDO76641.1 - 0.081 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding GCV_H PF01597.14 CDO76642.1 - 1.6e-43 147.2 0.9 1.9e-43 147.0 0.6 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 CDO76642.1 - 2.6e-05 23.7 0.1 5.5e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 CDO76642.1 - 8.6e-05 22.2 0.2 0.00033 20.3 0.0 1.9 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.17 CDO76642.1 - 0.062 13.3 0.3 0.91 9.6 0.2 2.2 1 1 1 2 2 2 0 Peptidase family M23 DUF2118 PF09891.4 CDO76642.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ESSS PF10183.4 CDO76643.1 - 7e-27 93.8 0.3 8.6e-27 93.6 0.2 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GRIP PF01465.15 CDO76644.1 - 6.9e-09 35.0 0.1 1.6e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 GRIP domain Med5 PF08689.5 CDO76644.1 - 3.7e-08 31.6 0.0 1.1e-07 30.0 0.1 4.5 3 2 0 3 3 3 2 Mediator complex subunit Med5 DUF4201 PF13870.1 CDO76644.1 - 0.002 17.5 14.1 0.002 17.5 9.8 5.4 2 1 3 5 5 5 1 Domain of unknown function (DUF4201) IncA PF04156.9 CDO76644.1 - 0.049 13.2 96.9 0.016 14.7 9.3 5.6 1 1 3 5 5 5 0 IncA protein Cation_efflux PF01545.16 CDO76645.1 - 3.6e-74 249.4 7.4 4.8e-41 140.7 0.1 2.0 2 0 0 2 2 2 2 Cation efflux family Zip PF02535.17 CDO76645.1 - 0.022 13.8 6.8 0.047 12.7 4.7 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter UBN2_2 PF14227.1 CDO76648.1 - 6.2e-15 54.8 0.0 1.1e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO76648.1 - 2.6e-10 40.1 0.0 3.8e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO76648.1 - 0.058 13.0 0.2 0.18 11.4 0.1 1.9 1 0 0 1 1 1 0 GAG-pre-integrase domain BRF1 PF07741.8 CDO76648.1 - 1.3 9.2 4.5 5.3 7.3 0.4 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain GMC_oxred_C PF05199.8 CDO76651.1 - 2.8e-17 63.3 0.1 3.2e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DUF976 PF06162.7 CDO76651.1 - 0.035 13.6 0.1 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF976) GMC_oxred_N PF00732.14 CDO76652.1 - 5.6e-49 166.8 0.0 2.5e-27 95.8 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO76652.1 - 7.5e-34 117.0 0.0 1.2e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 CDO76652.1 - 0.011 15.7 0.1 0.03 14.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO76652.1 - 0.011 14.6 0.1 0.25 10.1 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDO76652.1 - 0.015 14.1 0.1 0.047 12.5 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 CDO76652.1 - 0.12 12.4 0.2 4.8 7.1 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CDO76652.1 - 0.13 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GMC_oxred_N PF00732.14 CDO76653.1 - 6.7e-41 140.3 0.0 1.5e-40 139.1 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO76653.1 - 2.9e-35 121.6 0.0 5e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Senescence PF06911.7 CDO76654.1 - 1e-12 48.1 13.3 1.7e-12 47.3 9.2 1.4 1 0 0 1 1 1 1 Senescence-associated protein DDE_3 PF13358.1 CDO76658.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO76658.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain UQ_con PF00179.21 CDO76659.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme peroxidase PF00141.18 CDO76660.1 - 9.1e-48 162.7 0.0 1.4e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Arrestin_C PF02752.17 CDO76661.1 - 4.3e-14 52.7 0.1 1.1e-09 38.5 0.2 3.2 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CDO76661.1 - 1e-09 38.3 0.0 4.5e-08 33.0 0.0 2.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CDO76661.1 - 0.0027 17.2 0.1 0.0084 15.6 0.0 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like DDE_Tnp_4 PF13359.1 CDO76663.1 - 1.1e-13 51.0 0.0 2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease KcnmB2_inactiv PF09303.5 CDO76663.1 - 0.12 12.1 1.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 KCNMB2, ball and chain domain F-box-like PF12937.2 CDO76664.1 - 4e-05 23.2 0.9 8.6e-05 22.1 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO76664.1 - 0.00068 19.2 0.8 0.0024 17.4 0.6 2.0 1 0 0 1 1 1 1 F-box domain Methyltransf_22 PF13383.1 CDO76665.1 - 9.5e-10 38.4 0.8 0.00072 19.1 0.1 2.7 2 1 1 3 3 3 2 Methyltransferase domain TLD PF07534.11 CDO76666.1 - 8.1e-35 119.8 0.0 1.3e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 TLD HSP20 PF00011.16 CDO76667.1 - 2.8e-26 91.3 0.7 3.4e-26 91.0 0.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 CDO76667.1 - 0.0049 17.3 0.4 0.79 10.3 0.1 2.1 2 0 0 2 2 2 2 CS domain BON PF04972.12 CDO76667.1 - 0.018 14.7 0.2 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 BON domain HMA PF00403.21 CDO76667.1 - 0.026 14.6 0.1 2.2 8.5 0.1 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain DUF4097 PF13349.1 CDO76667.1 - 0.071 12.6 0.1 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) ubiquitin PF00240.18 CDO76668.1 - 0.25 10.7 0.0 0.64 9.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family BTB PF00651.26 CDO76671.1 - 3.3e-12 46.3 0.1 2.1e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain adh_short_C2 PF13561.1 CDO76672.1 - 8.6e-18 64.9 0.0 2.2e-17 63.6 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO76672.1 - 7.6e-13 48.7 3.1 1.1e-10 41.6 2.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO76672.1 - 1.2e-05 25.0 0.6 6.7e-05 22.6 0.2 2.0 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 CDO76673.1 - 6.2e-17 62.1 0.0 1.7e-15 57.4 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO76673.1 - 2.4e-11 43.8 1.7 1.8e-06 27.9 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 CDO76673.1 - 0.021 14.4 0.1 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.3 CDO76673.1 - 0.055 13.2 0.1 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 CDO76674.1 - 4.2e-25 88.8 0.0 5.4e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CDO76674.1 - 6e-25 88.0 0.5 7.8e-25 87.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO76674.1 - 3.8e-13 49.5 0.1 5.5e-13 48.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Thymidylat_synt PF00303.14 CDO76675.1 - 3.2e-112 373.9 0.0 3.6e-112 373.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase TPR_12 PF13424.1 CDO76676.1 - 2.2 8.2 29.8 1.2 9.0 1.9 6.6 5 2 2 7 7 7 0 Tetratricopeptide repeat Peptidase_C50 PF03568.12 CDO76677.1 - 3.1e-97 325.6 0.0 3.7e-97 325.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.2 CDO76677.1 - 0.0027 16.8 0.0 1 8.4 0.0 2.3 1 1 1 2 2 2 2 CHAT domain G-alpha PF00503.15 CDO76678.1 - 4.7e-116 387.6 0.0 5.8e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CDO76678.1 - 2.3e-10 39.9 0.0 3.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 CDO76678.1 - 0.00021 20.7 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CDO76678.1 - 0.034 13.6 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family GPP34 PF05719.6 CDO76679.1 - 1.4e-50 172.1 3.4 1.8e-50 171.8 2.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Chs3p PF12271.3 CDO76680.1 - 2.1e-46 158.2 11.9 4.2e-44 150.6 8.2 2.4 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit DUF2781 PF10914.3 CDO76680.1 - 0.0012 18.6 1.3 0.0012 18.6 0.9 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2781) FAD_binding_3 PF01494.14 CDO76682.1 - 1e-12 47.7 0.1 2.2e-12 46.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 CDO76682.1 - 4.6e-12 45.5 1.5 2.2e-05 23.5 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CDO76682.1 - 6e-07 29.7 0.1 0.00021 21.6 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CDO76682.1 - 4.1e-06 26.1 0.3 0.021 13.9 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CDO76682.1 - 0.00017 21.5 0.3 0.0004 20.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CDO76682.1 - 0.00017 20.6 0.3 0.0061 15.5 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 CDO76682.1 - 0.00037 19.0 0.1 0.0016 16.9 0.1 1.8 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 CDO76682.1 - 0.00073 18.2 0.0 0.097 11.2 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 CDO76682.1 - 0.00085 18.2 0.4 0.0042 15.9 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 CDO76682.1 - 0.0024 17.9 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDO76682.1 - 0.0073 16.2 0.1 0.023 14.5 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CDO76682.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 CDO76682.1 - 0.039 13.0 1.8 0.094 11.7 1.2 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 CDO76682.1 - 0.048 12.5 0.6 0.083 11.7 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 CDO76682.1 - 0.055 12.5 0.0 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Con-6 PF10346.4 CDO76683.1 - 5.8e-37 124.8 13.2 2.9e-16 58.5 1.9 3.2 3 0 0 3 3 3 3 Conidiation protein 6 SpoIIIAH PF12685.2 CDO76683.1 - 0.00093 18.7 1.3 0.025 14.0 0.1 2.4 2 0 0 2 2 2 1 SpoIIIAH-like protein Med3 PF11593.3 CDO76683.1 - 0.0032 16.7 1.6 0.005 16.1 1.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal YhzD PF14120.1 CDO76683.1 - 0.17 11.7 3.3 30 4.6 0.0 3.4 3 0 0 3 3 3 0 YhzD-like protein ATP-synt_DE PF00401.15 CDO76683.1 - 2.9 7.8 12.1 1.6 8.6 1.4 3.5 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Con-6 PF10346.4 CDO76684.1 - 4.1e-46 154.0 12.0 3.9e-16 58.1 1.2 3.5 3 0 0 3 3 3 3 Conidiation protein 6 FmdA_AmdA PF03069.10 CDO76684.1 - 1.6e-36 125.7 0.0 4.9e-23 81.4 0.0 3.0 2 1 1 3 3 3 2 Acetamidase/Formamidase family DUF2631 PF10939.3 CDO76684.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) Peptidase_M22 PF00814.20 CDO76685.1 - 1.4e-42 146.0 0.0 1.7e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Peptidase_C2 PF00648.16 CDO76685.1 - 0.092 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Calpain family cysteine protease DUF604 PF04646.7 CDO76685.1 - 0.1 11.7 0.2 0.24 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF604 XPG_I PF00867.13 CDO76686.1 - 1.7e-06 27.9 0.0 3.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region WIYLD PF10440.4 CDO76686.1 - 0.033 14.1 0.0 0.13 12.2 0.0 2.0 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain Amidohydro_3 PF07969.6 CDO76687.1 - 2e-72 244.6 0.4 2.6e-72 244.2 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CDO76687.1 - 2.3e-06 27.8 0.1 0.1 12.6 0.0 2.8 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 CDO76687.1 - 3.7e-05 23.5 0.0 0.0029 17.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 CDO76687.1 - 0.0034 17.1 0.0 0.0091 15.7 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase zf-rbx1 PF12678.2 CDO76688.1 - 6.4e-14 51.8 0.9 1.2e-13 50.9 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CDO76688.1 - 3.4e-11 42.7 9.1 5.8e-10 38.8 6.3 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CDO76688.1 - 1.1e-07 31.4 2.4 2.1e-07 30.4 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO76688.1 - 1.7e-06 27.6 4.8 4.1e-05 23.1 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO76688.1 - 3.1e-06 27.1 2.0 3.1e-06 27.1 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDO76688.1 - 2.1e-05 24.1 2.4 5.6e-05 22.7 1.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CDO76688.1 - 6.1e-05 22.6 4.3 0.0003 20.4 3.2 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 CDO76688.1 - 0.00042 20.0 3.1 0.0012 18.6 2.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CDO76688.1 - 0.0034 17.2 2.1 0.0077 16.0 1.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Transposase_28 PF04195.7 CDO76688.1 - 0.0092 15.2 0.9 0.45 9.7 0.0 2.4 2 0 0 2 2 2 1 Putative gypsy type transposon FANCL_C PF11793.3 CDO76688.1 - 0.043 13.7 0.3 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 CDO76688.1 - 1.4 8.5 4.0 0.77 9.3 0.8 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YqeY PF09424.5 CDO76689.1 - 2.3e-22 79.3 0.2 2.6e-22 79.2 0.1 1.0 1 0 0 1 1 1 1 Yqey-like protein polyprenyl_synt PF00348.12 CDO76691.1 - 7.3e-30 103.6 0.0 8.5e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DEAD PF00270.24 CDO76692.1 - 7e-13 48.4 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO76692.1 - 2.3e-12 46.6 0.0 2.3e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCHC_6 PF15288.1 CDO76692.1 - 9.1e-07 28.4 0.9 2.2e-06 27.2 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle ResIII PF04851.10 CDO76692.1 - 0.15 11.8 0.0 0.49 10.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DLH PF01738.13 CDO76693.1 - 7e-26 90.8 0.0 1.4e-25 89.8 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CDO76693.1 - 1.2e-06 28.2 0.0 2.3e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO76693.1 - 6.9e-05 22.8 0.4 0.0081 16.0 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO76693.1 - 0.015 14.8 0.0 0.71 9.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold EI24 PF07264.6 CDO76694.1 - 0.0031 16.9 0.1 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Cofilin_ADF PF00241.15 CDO76695.1 - 1.7e-41 141.0 0.4 1.9e-41 140.9 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EntA_Immun PF08951.5 CDO76695.1 - 0.007 16.4 0.4 0.01 15.9 0.3 1.2 1 0 0 1 1 1 1 Enterocin A Immunity CH PF00307.26 CDO76696.1 - 1.3e-28 99.1 0.6 5.6e-13 48.8 0.0 3.6 2 1 1 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 CDO76696.1 - 1.1e-16 60.5 0.0 7.1e-16 57.9 0.0 2.5 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 CDO76696.1 - 3.7e-11 42.5 0.2 7.3e-08 31.9 0.1 2.8 2 0 0 2 2 2 2 CAMSAP CH domain Spectrin PF00435.16 CDO76696.1 - 0.00018 21.7 0.9 0.16 12.2 0.1 3.0 2 1 0 2 2 2 2 Spectrin repeat EF-hand_6 PF13405.1 CDO76696.1 - 0.00022 20.8 0.0 0.0039 16.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 CDO76696.1 - 0.0055 16.8 0.3 0.024 14.7 0.2 2.1 1 1 0 1 1 1 1 EF-hand domain pair CENP-F_leu_zip PF10473.4 CDO76696.1 - 0.013 15.3 2.7 0.036 13.9 1.9 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_1 PF00036.27 CDO76696.1 - 0.016 14.4 0.0 0.058 12.7 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 CDO76696.1 - 0.02 14.4 0.3 2.6 7.7 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain pair Ribosomal_L36e PF01158.13 CDO76696.1 - 0.021 14.7 0.1 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L36e DUF4061 PF13270.1 CDO76696.1 - 0.021 14.9 3.6 0.098 12.7 0.4 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) SSrecog PF03531.9 CDO76697.1 - 8.1e-75 250.9 0.2 8.1e-75 250.9 0.2 1.8 2 1 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CDO76697.1 - 3.1e-24 84.7 0.1 2.3e-23 81.9 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2779 PF11074.3 CDO76697.1 - 0.12 12.3 1.1 0.43 10.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function(DUF2779) DUF3966 PF13110.1 CDO76697.1 - 0.61 9.9 5.1 0.16 11.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3966) CRA PF06589.6 CDO76699.1 - 0.17 11.1 0.1 0.17 11.1 0.1 1.9 2 1 1 3 3 3 0 Circumsporozoite-related antigen (CRA) DLH PF01738.13 CDO76700.1 - 3.6e-28 98.3 0.0 8.7e-28 97.0 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CDO76700.1 - 2.5e-08 33.7 0.0 4.6e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO76700.1 - 3.1e-05 23.9 0.9 0.015 15.2 0.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO76700.1 - 0.026 14.0 0.0 0.59 9.6 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold Toxin_59 PF15537.1 CDO76700.1 - 0.1 12.6 0.1 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Putative toxin 59 Pkinase PF00069.20 CDO76701.1 - 1.9e-47 161.5 0.0 3.7e-47 160.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76701.1 - 8.6e-23 80.7 0.0 2e-22 79.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO76701.1 - 2e-05 23.6 0.0 4.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO76701.1 - 0.00039 20.2 0.0 0.0013 18.5 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CDO76701.1 - 0.43 9.3 0.1 0.65 8.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase alpha-hel2 PF14456.1 CDO76701.1 - 3.1 6.4 8.7 2.4 6.8 4.7 1.7 2 0 0 2 2 2 0 Alpha-helical domain 2 TPR_MLP1_2 PF07926.7 CDO76702.1 - 2.4e-21 75.8 22.5 2.4e-21 75.8 15.6 17.5 6 4 7 14 14 14 7 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 CDO76702.1 - 1.8e-05 24.5 12.7 1.8e-05 24.5 8.8 16.9 7 5 7 16 16 16 3 Tropomyosin like Mob1_phocein PF03637.12 CDO76703.1 - 9.8e-65 217.4 0.8 1.2e-64 217.1 0.6 1.1 1 0 0 1 1 1 1 Mob1/phocein family Nup160 PF11715.3 CDO76704.1 - 0.044 11.9 0.0 0.055 11.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CDO76704.1 - 0.098 12.9 0.0 24 5.3 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Aldo_ket_red PF00248.16 CDO76707.1 - 7e-40 136.6 0.0 7.8e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S13 PF00416.17 CDO76708.1 - 4.7e-41 139.5 1.1 5.7e-41 139.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CDO76708.1 - 0.0039 15.7 0.0 0.0041 15.7 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 CDO76708.1 - 0.0086 16.0 0.2 0.025 14.5 0.1 1.8 2 1 0 2 2 2 1 Helix-hairpin-helix motif DUF3196 PF11428.3 CDO76708.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3196) Rotavirus_VP1 PF12289.3 CDO76708.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Rotavirus VP1 structural protein PP28 PF10252.4 CDO76708.1 - 0.14 12.2 0.4 0.34 10.9 0.3 1.7 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 CBFB_NFYA PF02045.10 CDO76710.1 - 7.7e-29 100.0 6.9 7.7e-29 100.0 4.8 1.8 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Neur_chan_memb PF02932.11 CDO76710.1 - 5.9 6.7 7.3 1.1e+02 2.4 5.0 2.1 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lin-8 PF03353.10 CDO76711.1 - 0.33 10.1 3.4 0.42 9.8 2.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Apc15p PF05841.6 CDO76711.1 - 1.1 10.0 9.5 1.7 9.3 6.6 1.3 1 0 0 1 1 1 0 Apc15p protein PAT1 PF09770.4 CDO76711.1 - 2.2 6.4 10.7 2.1 6.4 7.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pyrid_oxidase_2 PF13883.1 CDO76711.1 - 3.9 7.2 7.2 0.28 10.9 0.4 1.9 1 1 1 2 2 2 0 Pyridoxamine 5'-phosphate oxidase HeH PF12949.2 CDO76712.1 - 2e-07 30.4 1.4 4.8e-07 29.2 1.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain Rho_N PF07498.7 CDO76712.1 - 0.00062 19.4 0.4 0.0012 18.5 0.3 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.22 CDO76712.1 - 0.002 17.5 0.2 0.0053 16.2 0.1 1.7 1 0 0 1 1 1 1 SAP domain PAP1 PF08601.5 CDO76712.1 - 0.27 10.8 13.5 0.3 10.7 9.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 PAT1 PF09770.4 CDO76712.1 - 0.5 8.5 11.1 0.52 8.4 7.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CDO76712.1 - 3.1 5.9 10.7 3.7 5.7 7.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Golgin_A5 PF09787.4 CDO76712.1 - 7.2 5.0 12.0 11 4.4 8.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 HET PF06985.6 CDO76714.1 - 2.9e-17 63.1 8.1 2.7e-14 53.5 1.7 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-C2H2_2 PF12756.2 CDO76715.1 - 4.1e-36 123.1 12.3 5.1e-31 106.7 0.1 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CDO76715.1 - 6.4e-08 32.5 1.1 6.4e-08 32.5 0.7 2.2 3 0 0 3 3 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CDO76715.1 - 1.2e-07 31.6 1.4 1.2e-07 31.6 1.0 3.4 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Pox_Ag35 PF03286.9 CDO76715.1 - 0.0017 17.9 9.6 0.0017 17.9 6.6 2.4 2 1 0 2 2 2 1 Pox virus Ag35 surface protein zf-C2H2_4 PF13894.1 CDO76715.1 - 0.0018 18.4 0.3 0.0018 18.4 0.2 4.4 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CDO76715.1 - 0.024 14.5 0.6 0.024 14.5 0.4 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO76715.1 - 0.027 14.8 0.4 0.027 14.8 0.3 4.3 5 0 0 5 5 5 0 Zinc finger, C2H2 type CDC45 PF02724.9 CDO76715.1 - 0.093 10.7 7.3 0.13 10.3 5.0 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-DBF PF07535.7 CDO76715.1 - 0.1 12.2 0.3 0.1 12.2 0.2 2.6 3 0 0 3 3 3 0 DBF zinc finger DUF3449 PF11931.3 CDO76715.1 - 4 6.9 20.3 0.14 11.6 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) Spore_coat_CotO PF14153.1 CDO76715.1 - 4 6.8 10.7 0.15 11.4 1.9 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Rax2 PF12768.2 CDO76716.1 - 2.5e-87 292.6 18.9 3e-72 243.1 1.5 5.0 4 2 0 4 4 4 4 Cortical protein marker for cell polarity Kelch_6 PF13964.1 CDO76716.1 - 3.1e-05 23.9 10.3 0.17 12.1 0.1 6.7 7 0 0 7 7 7 2 Kelch motif SH3_1 PF00018.23 CDO76716.1 - 0.0021 17.4 0.1 0.0041 16.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain Dioxygenase_C PF00775.16 CDO76717.1 - 3.5e-50 169.8 0.0 5.3e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 CDO76717.1 - 1e-15 57.4 0.0 1.7e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus DUF1279 PF06916.8 CDO76718.1 - 7.1e-19 67.8 0.0 1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3248 PF11609.3 CDO76718.1 - 0.048 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) SAM_decarbox PF01536.11 CDO76719.1 - 1.3e-65 221.2 0.0 8.8e-53 179.0 0.0 2.4 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase PP2C PF00481.16 CDO76720.1 - 6.4e-23 81.4 0.0 4.4e-22 78.7 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CDO76720.1 - 2.1e-07 30.5 0.0 8.5e-07 28.5 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CDO76720.1 - 0.0057 16.3 0.0 2 8.0 0.0 2.5 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Dfp1_Him1_M PF08630.5 CDO76723.1 - 3.8e-25 88.0 0.0 8e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 CDO76723.1 - 2e-22 78.5 1.1 5e-22 77.3 0.7 1.7 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 CDO76723.1 - 0.0047 17.0 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Spc97_Spc98 PF04130.8 CDO76725.1 - 2.9e-25 88.5 0.0 6.4e-24 84.1 0.0 2.1 1 1 0 1 1 1 1 Spc97 / Spc98 family AAA_22 PF13401.1 CDO76726.1 - 7e-12 45.6 0.0 1.6e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CDO76726.1 - 3.4e-09 37.0 0.0 8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDO76726.1 - 4.8e-09 36.4 0.0 9.9e-08 32.1 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CDO76726.1 - 7.8e-06 25.5 0.1 2.8e-05 23.8 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 CDO76726.1 - 0.0001 21.3 0.0 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 CDO76726.1 - 0.00025 20.7 0.0 0.00054 19.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 CDO76726.1 - 0.00047 19.1 0.0 0.00074 18.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 CDO76726.1 - 0.0038 16.9 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_30 PF13604.1 CDO76726.1 - 0.0045 16.5 0.0 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CDO76726.1 - 0.0072 16.0 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 CDO76726.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 CDO76726.1 - 0.022 14.7 0.1 0.05 13.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CDO76726.1 - 0.024 14.3 0.1 0.083 12.5 0.1 1.9 1 1 0 1 1 1 0 NTPase AAA_11 PF13086.1 CDO76726.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CDO76726.1 - 0.042 13.2 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 CDO76726.1 - 0.046 12.7 0.1 3.6 6.4 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_25 PF13481.1 CDO76726.1 - 0.053 12.9 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 CDO76726.1 - 0.059 12.2 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Zot PF05707.7 CDO76726.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) RNA_helicase PF00910.17 CDO76726.1 - 0.088 12.9 0.0 0.34 11.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 CDO76726.1 - 0.21 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein UvrD-helicase PF00580.16 CDO76726.1 - 0.25 10.5 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain BTB PF00651.26 CDO76729.1 - 0.097 12.6 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain DUF1423 PF07227.6 CDO76730.1 - 3.5 6.2 9.0 0.32 9.6 3.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) Ank PF00023.25 CDO76734.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeat Lactonase PF10282.4 CDO76735.1 - 1.1e-48 166.1 0.0 1.2e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DHQS PF01959.11 CDO76735.1 - 0.018 13.7 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) p450 PF00067.17 CDO76737.1 - 6e-63 212.9 0.1 1.1e-59 202.2 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 E1-E2_ATPase PF00122.15 CDO76739.1 - 4.7e-78 261.3 1.3 4.7e-78 261.3 0.9 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CDO76739.1 - 9.1e-37 126.3 0.4 9.1e-37 126.3 0.3 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CDO76739.1 - 2.7e-24 86.7 0.0 1.2e-23 84.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDO76739.1 - 1.2e-14 54.0 0.0 6.6e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CDO76739.1 - 1.9e-13 51.0 0.0 6.2e-13 49.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CDO76739.1 - 5.7e-13 48.1 0.0 1.7e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CDO76739.1 - 1.7e-05 24.4 1.7 0.0011 18.5 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.7 CDO76739.1 - 0.0065 16.0 0.0 0.0065 16.0 0.0 2.5 4 0 0 4 4 4 1 Positive regulator of sigma(E), RseC/MucC RVT_1 PF00078.22 CDO76740.1 - 6.4e-38 130.2 0.0 1.3e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO76740.1 - 7.4e-18 65.1 0.1 2.1e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 CDO76740.1 - 5.5e-09 36.3 0.2 1.3e-08 35.0 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.1 CDO76740.1 - 0.0035 17.6 5.0 0.0038 17.4 1.1 2.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase FlxA PF14282.1 CDO76740.1 - 0.0059 16.5 1.3 0.012 15.5 0.9 1.4 1 0 0 1 1 1 1 FlxA-like protein AAT PF03417.11 CDO76742.1 - 2.8e-18 66.2 0.0 4.6e-18 65.5 0.0 1.3 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 CDO76742.1 - 0.036 14.4 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CoA_transf_3 PF02515.12 CDO76743.1 - 2.8e-49 166.9 0.0 5.3e-49 166.0 0.0 1.5 2 0 0 2 2 2 1 CoA-transferase family III RhoGEF PF00621.15 CDO76744.1 - 6.4e-34 117.4 0.0 1.6e-33 116.1 0.0 1.7 1 1 0 1 1 1 1 RhoGEF domain FAD_binding_4 PF01565.18 CDO76745.1 - 1.5e-06 27.7 0.1 0.00033 20.1 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain Aldo_ket_red PF00248.16 CDO76747.1 - 7.4e-59 198.8 0.0 8.6e-59 198.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2361 PF10153.4 CDO76748.1 - 9.6e-32 109.5 6.3 9.6e-32 109.5 4.4 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) TFIIA PF03153.8 CDO76748.1 - 0.0089 15.9 10.6 0.011 15.6 7.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDE_3 PF13358.1 CDO76750.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO76750.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain UPF0552 PF10574.4 CDO76751.1 - 0.035 13.5 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0552 U-box PF04564.10 CDO76751.1 - 0.059 13.3 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 U-box domain DAHP_synth_1 PF00793.15 CDO76752.1 - 8e-54 182.1 0.0 1.1e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family PIH1 PF08190.7 CDO76754.1 - 5.3e-10 39.2 0.1 3.9e-06 26.5 0.0 3.2 3 0 0 3 3 3 3 pre-RNA processing PIH1/Nop17 LIM PF00412.17 CDO76755.1 - 3.1e-20 72.0 11.7 5.4e-12 45.5 0.5 2.4 2 0 0 2 2 2 2 LIM domain zf-ribbon_3 PF13248.1 CDO76755.1 - 2.7e-05 23.2 13.5 0.049 12.8 0.8 3.6 2 1 1 3 3 3 3 zinc-ribbon domain Zn-ribbon_8 PF09723.5 CDO76755.1 - 0.00041 20.2 11.2 0.057 13.3 0.5 3.3 3 0 0 3 3 3 2 Zinc ribbon domain DZR PF12773.2 CDO76755.1 - 0.0027 17.4 17.4 0.15 11.8 2.6 3.3 2 1 0 2 2 2 2 Double zinc ribbon DUF1451 PF07295.6 CDO76755.1 - 0.088 12.5 10.6 0.38 10.5 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Cytochrom_c3_2 PF14537.1 CDO76755.1 - 3.3 8.1 11.5 8.6 6.7 2.2 2.5 2 0 0 2 2 2 0 Cytochrome c3 Tmemb_9 PF05434.6 CDO76755.1 - 4.3 7.0 7.0 2.1 8.0 0.6 2.5 2 0 0 2 2 2 0 TMEM9 zf-MYND PF01753.13 CDO76755.1 - 7.8 6.4 13.4 11 6.0 0.5 3.6 3 1 0 3 3 3 0 MYND finger eIF-5a PF01287.15 CDO76756.1 - 1.5e-27 95.3 0.2 2.7e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CDO76756.1 - 3.8e-05 23.2 0.8 7.1e-05 22.3 0.6 1.5 1 0 0 1 1 1 1 KOW motif TcdB_toxin_midN PF12256.3 CDO76756.1 - 0.14 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region EFP_N PF08207.7 CDO76756.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain DivIC PF04977.10 CDO76758.1 - 0.076 12.5 1.1 8.7 5.9 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 CDO76758.1 - 2.1 8.6 6.0 5.5 7.3 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) HALZ PF02183.13 CDO76758.1 - 4.4 7.0 5.9 14 5.4 0.1 3.1 2 1 0 3 3 3 0 Homeobox associated leucine zipper Complex1_LYR PF05347.10 CDO76760.1 - 1e-09 38.0 0.7 1.8e-09 37.2 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CDO76760.1 - 1.1e-07 31.8 0.3 2.1e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Mad3_BUB1_I PF08311.7 CDO76760.1 - 0.058 13.1 0.2 0.076 12.8 0.1 1.2 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 PP28 PF10252.4 CDO76761.1 - 1.5e-22 79.3 17.8 1.5e-22 79.3 12.3 3.1 3 1 0 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Cut8_N PF14482.1 CDO76761.1 - 0.056 13.4 0.8 0.19 11.7 0.5 2.0 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Sporozoite_P67 PF05642.6 CDO76761.1 - 0.45 8.3 6.8 0.58 7.9 4.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hex_IIIa PF02455.11 CDO76761.1 - 8.4 4.9 15.7 11 4.5 10.9 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) PPR_3 PF13812.1 CDO76762.1 - 0.0024 18.0 1.2 0.88 10.0 0.0 4.3 5 0 0 5 5 5 1 Pentatricopeptide repeat domain DUF3628 PF12300.3 CDO76762.1 - 0.067 13.2 0.1 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) RRM_1 PF00076.17 CDO76763.1 - 2.7e-10 39.7 0.0 2.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO76763.1 - 4e-09 36.3 0.0 0.00099 19.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO76763.1 - 2.6e-06 27.1 0.0 1.2e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO76763.1 - 0.024 14.3 0.0 5.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF1777 PF08648.7 CDO76763.1 - 0.042 13.5 63.2 0.081 12.6 43.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RINGv PF12906.2 CDO76764.1 - 9.7e-07 28.7 7.2 9.7e-07 28.7 5.0 1.7 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 CDO76764.1 - 0.00028 20.6 5.6 0.00066 19.4 3.9 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 CDO76764.1 - 0.002 18.0 3.7 0.002 18.0 2.5 1.6 2 0 0 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.2 CDO76764.1 - 0.0025 17.8 4.6 0.0059 16.6 3.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CDO76764.1 - 0.12 12.4 5.4 0.42 10.6 3.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO76764.1 - 0.19 11.4 3.6 0.37 10.5 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO76764.1 - 0.21 11.2 5.0 0.47 10.1 3.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tmpp129 PF10272.4 CDO76764.1 - 0.68 8.6 4.4 0.98 8.0 3.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor GTP_EFTU PF00009.22 CDO76765.1 - 3.9e-37 127.5 0.1 7.1e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CDO76765.1 - 2.9e-36 123.3 0.2 6.7e-36 122.2 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CDO76765.1 - 4.8e-11 42.6 1.1 1.1e-10 41.5 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CDO76765.1 - 0.035 14.0 0.0 0.095 12.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gp_dh_C PF02800.15 CDO76766.1 - 1e-72 242.7 0.1 1.4e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CDO76766.1 - 6.6e-55 185.2 0.0 2.2e-54 183.5 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain HET PF06985.6 CDO76767.1 - 4.5e-07 30.1 0.0 6.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SDA1 PF05285.7 CDO76768.1 - 6 6.0 16.5 0.12 11.5 5.7 2.0 2 0 0 2 2 2 0 SDA1 RasGEF PF00617.14 CDO76769.1 - 1.2e-26 93.6 0.0 1.9e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CDO76769.1 - 1.1e-10 41.5 0.3 3e-10 40.1 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Aconitase PF00330.15 CDO76770.1 - 1.8e-177 590.5 0.3 4e-177 589.3 0.2 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CDO76770.1 - 1.6e-46 157.6 0.0 3e-46 156.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Fungal_trans PF04082.13 CDO76771.1 - 2.2e-13 49.7 0.1 8e-13 47.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 CDO76772.1 - 2.9e-24 85.1 0.4 5.2e-24 84.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CDO76772.1 - 5e-07 29.5 0.0 1.4e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 CDO76774.1 - 1.6e-21 76.2 0.8 3.1e-21 75.3 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CDO76774.1 - 6.5e-06 25.9 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ank_2 PF12796.2 CDO76774.1 - 0.033 14.5 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) FAD_binding_4 PF01565.18 CDO76775.1 - 1.5e-14 53.6 0.0 7.4e-14 51.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 CDO76775.1 - 2.1e-05 24.3 0.0 4.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Amidase PF01425.16 CDO76776.1 - 3.3e-65 220.6 0.0 5.6e-65 219.9 0.0 1.4 1 1 0 1 1 1 1 Amidase ADH_N PF08240.7 CDO76776.1 - 2.1e-24 85.3 0.1 4.8e-24 84.2 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO76776.1 - 6.3e-18 64.5 0.0 2.8e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CDO76776.1 - 0.018 14.2 0.0 0.08 12.0 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WSN PF02206.13 CDO76776.1 - 0.055 13.2 0.8 0.35 10.6 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function CPSase_L_chain PF00289.17 CDO76776.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain BTB PF00651.26 CDO76777.1 - 4.1e-06 26.7 0.0 7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Amidase PF01425.16 CDO76779.1 - 9.9e-76 255.3 0.0 3.7e-75 253.4 0.0 1.7 1 1 0 1 1 1 1 Amidase zf-CCCH PF00642.19 CDO76780.1 - 5.9e-05 22.6 6.7 0.0011 18.5 1.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CDO76780.1 - 0.5 10.4 11.1 0.18 11.8 1.7 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 CDO76781.1 - 5.7e-56 189.5 0.0 9.1e-47 159.3 0.0 2.9 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76781.1 - 4.3e-22 78.4 0.0 5.6e-16 58.4 0.0 2.8 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CDO76781.1 - 0.00013 21.0 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO76781.1 - 0.041 13.6 0.4 0.093 12.4 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CDO76781.1 - 0.054 12.5 0.0 0.41 9.6 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CDO76781.1 - 0.21 10.3 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 BCDHK_Adom3 PF10436.4 CDO76782.1 - 9.5e-62 207.3 0.0 2.5e-61 205.9 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase 6PGD PF00393.14 CDO76782.1 - 2.6e-57 194.2 0.1 5.7e-39 134.0 0.0 2.2 2 0 0 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CDO76782.1 - 3.3e-33 114.8 0.0 5.7e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HATPase_c PF02518.21 CDO76782.1 - 6.3e-19 67.7 0.0 2.6e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3HCDH_N PF02737.13 CDO76782.1 - 1.7e-09 37.5 0.0 3.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CDO76782.1 - 2.2e-06 27.5 0.0 4.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HATPase_c_3 PF13589.1 CDO76782.1 - 0.0022 17.6 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2-Hacid_dh_C PF02826.14 CDO76782.1 - 0.0039 16.3 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CDO76782.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 CDO76782.1 - 0.028 14.8 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CDO76782.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PAS_9 PF13426.1 CDO76783.1 - 1.8e-19 70.0 0.0 1.4e-07 31.7 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.5 CDO76783.1 - 1.7e-11 44.0 0.1 1.1e-05 25.4 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 CDO76783.1 - 7.5e-11 41.8 0.0 0.00011 22.0 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.6 CDO76783.1 - 1.8e-09 37.5 0.0 7.9e-05 22.6 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 CDO76783.1 - 7.9e-05 22.5 0.0 0.0067 16.3 0.0 3.0 3 0 0 3 3 3 1 PAS domain Kinetocho_Slk19 PF12709.2 CDO76783.1 - 0.17 11.9 0.3 0.31 11.1 0.2 1.3 1 0 0 1 1 1 0 Central kinetochore-associated F_bP_aldolase PF01116.15 CDO76784.1 - 4.8e-96 321.2 0.0 5.4e-96 321.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.6 CDO76784.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Torsin HhH-GPD PF00730.20 CDO76786.1 - 2.5e-05 24.5 0.0 2.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_L16 PF00252.13 CDO76787.1 - 1e-33 115.9 0.0 1.3e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RTBV_P46 PF06216.6 CDO76787.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Glyco_hydro_20 PF00728.17 CDO76788.1 - 4.8e-61 206.8 0.0 6.9e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CDO76788.1 - 5e-12 46.5 0.0 9.5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CDO76788.1 - 2.6e-05 24.7 0.1 0.00014 22.4 0.0 2.3 2 2 1 3 3 3 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_97 PF10566.4 CDO76788.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 97 APH PF01636.18 CDO76789.1 - 8e-17 61.7 0.1 1.1e-16 61.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO76789.1 - 0.00011 21.8 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 CDO76789.1 - 0.002 17.4 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 CDO76789.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain OPT PF03169.10 CDO76790.1 - 3.8e-57 194.1 24.0 4.7e-57 193.8 16.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.20 CDO76791.1 - 4.5e-57 193.1 0.0 1.1e-56 191.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76791.1 - 1.6e-28 99.4 0.0 1.4e-27 96.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO76791.1 - 4.4e-07 29.1 0.0 7.7e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDO76791.1 - 0.019 14.7 0.3 0.23 11.1 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CDO76791.1 - 0.17 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL E3_UbLigase_R4 PF13764.1 CDO76791.1 - 0.24 9.2 0.1 0.34 8.7 0.0 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 DUF4218 PF13960.1 CDO76792.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Hexapep PF00132.19 CDO76794.1 - 5.9e-08 31.8 20.8 0.0035 16.7 0.3 4.4 3 2 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CDO76794.1 - 0.011 15.2 4.5 0.011 15.2 3.1 2.9 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Meleagrin PF08189.6 CDO76794.1 - 0.097 12.1 0.5 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 Meleagrin/Cygnin family BTB PF00651.26 CDO76795.1 - 2.1e-08 34.1 0.0 6.2e-07 29.3 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain SOG2 PF10428.4 CDO76795.1 - 0.09 11.4 11.3 0.02 13.5 5.4 1.8 2 0 0 2 2 2 0 RAM signalling pathway protein BRCT PF00533.21 CDO76796.1 - 8.5e-11 41.8 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CDO76796.1 - 1.4e-07 31.2 0.1 1.5e-06 27.9 0.1 2.3 1 1 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 CDO76796.1 - 1.4e-05 25.1 0.4 4.2e-05 23.5 0.3 1.8 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 CDO76796.1 - 0.0056 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) MAP65_ASE1 PF03999.7 CDO76796.1 - 1.9 6.9 4.3 2.4 6.6 3.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Lin-8 PF03353.10 CDO76797.1 - 0.13 11.5 1.6 0.2 10.8 1.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4470 PF14737.1 CDO76798.1 - 1.3e-19 69.7 0.0 3.9e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 CDO76798.1 - 1.8e-09 37.3 17.4 3.8e-09 36.2 12.0 1.6 1 0 0 1 1 1 1 MYND finger Transp_cyt_pur PF02133.10 CDO76799.1 - 3.1e-95 319.3 40.9 3.7e-95 319.0 28.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sel1 PF08238.7 CDO76800.1 - 4.2e-14 52.6 19.6 1.6e-06 28.5 0.0 7.6 8 0 0 8 8 8 3 Sel1 repeat ADH_N PF08240.7 CDO76800.1 - 9.7e-09 34.9 0.4 2e-08 33.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO76800.1 - 1.6e-06 27.6 0.5 3.7e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TPR_11 PF13414.1 CDO76800.1 - 0.02 14.5 2.9 0.027 14.1 0.1 2.6 3 0 0 3 3 3 0 TPR repeat TPR_8 PF13181.1 CDO76800.1 - 0.034 13.9 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CDO76800.1 - 0.043 13.7 3.8 0.86 9.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CDO76800.1 - 0.15 11.7 3.6 0.44 10.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat vMSA PF00695.14 CDO76801.1 - 1.8 7.6 2.3 5 6.2 1.6 1.6 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus RVT_2 PF07727.9 CDO76804.1 - 6.1e-90 300.4 0.0 1e-89 299.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TMCO5 PF14992.1 CDO76805.1 - 0.00044 19.4 3.9 0.00083 18.5 2.7 1.4 1 0 0 1 1 1 1 TMCO5 family ASFV_J13L PF05568.6 CDO76805.1 - 0.0035 16.9 2.8 0.0072 15.8 2.0 1.5 1 0 0 1 1 1 1 African swine fever virus J13L protein Transposase_21 PF02992.9 CDO76806.1 - 8.6e-08 31.5 0.0 1.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO76806.1 - 0.00012 21.5 0.3 0.00023 20.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 CDO76809.1 - 1.1e-18 67.1 0.0 1.9e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO76809.1 - 0.00043 19.7 0.0 0.00092 18.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) OEP PF02321.13 CDO76810.1 - 0.14 11.7 3.1 0.23 11.0 2.1 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein CENP-Q PF13094.1 CDO76810.1 - 2.1 8.3 8.9 2.4 8.1 4.9 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Glyco_hydro_cc PF11790.3 CDO76811.1 - 0.038 13.3 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Adaptin_binding PF10199.4 CDO76812.1 - 0.12 12.7 4.4 0.3 11.3 3.1 1.6 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 ABC_tran_2 PF12848.2 CDO76812.1 - 0.33 10.8 7.5 0.72 9.7 5.2 1.5 1 0 0 1 1 1 0 ABC transporter CENP-F_leu_zip PF10473.4 CDO76815.1 - 4.1e-06 26.7 9.6 0.0013 18.5 2.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.6 CDO76815.1 - 0.00091 19.5 2.2 0.021 15.2 0.3 2.5 1 1 1 2 2 2 1 Syntaxin 6, N-terminal Mnd1 PF03962.10 CDO76815.1 - 0.0084 15.7 0.9 0.0084 15.7 0.6 2.1 1 1 1 2 2 2 1 Mnd1 family Syntaxin PF00804.20 CDO76815.1 - 0.022 14.9 1.5 0.05 13.7 0.6 2.0 1 1 1 2 2 2 0 Syntaxin DUF4200 PF13863.1 CDO76815.1 - 0.045 13.7 3.6 0.25 11.2 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) LLC1 PF14945.1 CDO76815.1 - 0.066 13.5 0.5 15 5.9 0.0 2.5 2 1 1 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF1451 PF07295.6 CDO76815.1 - 0.085 12.6 3.9 0.058 13.1 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) ERM PF00769.14 CDO76815.1 - 0.096 12.2 7.8 0.57 9.6 1.2 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family GLE1 PF07817.8 CDO76815.1 - 0.11 11.3 0.1 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 GLE1-like protein EMP24_GP25L PF01105.19 CDO76815.1 - 0.18 11.5 2.7 3.1 7.4 0.2 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD LPP PF04728.8 CDO76815.1 - 0.21 11.4 1.8 0.84 9.4 0.1 2.7 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Cortex-I_coil PF09304.5 CDO76815.1 - 0.21 11.6 0.2 0.21 11.6 0.1 2.7 1 1 2 3 3 3 0 Cortexillin I, coiled coil CALCOCO1 PF07888.6 CDO76815.1 - 0.25 9.5 10.9 0.72 8.0 7.5 1.6 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.3 CDO76815.1 - 0.26 11.2 9.4 0.14 12.0 0.9 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding MCC-bdg_PDZ PF10506.4 CDO76815.1 - 0.3 10.9 4.3 0.25 11.2 0.7 2.4 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome MCPsignal PF00015.16 CDO76815.1 - 0.62 9.5 6.8 1.7 8.1 0.5 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.6 CDO76815.1 - 0.83 8.2 4.7 1.3 7.5 3.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3552 PF12072.3 CDO76815.1 - 0.98 8.5 8.7 3 7.0 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Phage_GPO PF05929.6 CDO76815.1 - 1.8 7.7 8.0 0.44 9.7 1.6 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase APG6 PF04111.7 CDO76815.1 - 2.3 7.1 6.3 1.5 7.7 2.8 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 Suppressor_APC PF11414.3 CDO76815.1 - 2.8 7.7 6.4 0.49 10.2 0.3 2.5 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein Sad1_UNC PF07738.8 CDO76816.1 - 5.7e-10 39.1 0.0 0.0013 18.5 0.0 2.9 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal Catalase-rel PF06628.7 CDO76818.1 - 0.026 14.4 0.1 10 6.0 0.0 3.2 4 0 0 4 4 4 0 Catalase-related immune-responsive F-box PF00646.28 CDO76819.1 - 5.3e-08 32.3 0.0 1.2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO76819.1 - 5.5e-08 32.4 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like SRA1 PF07304.6 CDO76819.1 - 0.05 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) RNA_pol_Rpb2_2 PF04561.9 CDO76820.1 - 0.033 13.5 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 TFIIA PF03153.8 CDO76820.1 - 5.8 6.6 29.6 11 5.8 20.5 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Phosphodiest PF01663.17 CDO76821.1 - 3.4e-11 43.1 1.1 6.8e-11 42.0 0.3 1.7 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CDO76821.1 - 0.0017 17.5 0.0 0.0094 15.1 0.0 1.9 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 CDO76821.1 - 0.0028 17.1 0.6 0.0054 16.1 0.4 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Terpene_synth_C PF03936.11 CDO76822.1 - 0.003 16.8 0.0 0.04 13.1 0.0 2.0 1 1 1 2 2 2 1 Terpene synthase family, metal binding domain CRISPR_Cse1 PF09481.5 CDO76822.1 - 0.055 12.2 0.7 0.079 11.6 0.5 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) Rhodanese PF00581.15 CDO76823.1 - 3e-07 30.7 0.0 6.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain F-box-like PF12937.2 CDO76824.1 - 3e-07 30.0 1.5 7.1e-07 28.8 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 CDO76825.1 - 0.012 15.2 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.1 CDO76825.1 - 0.13 12.0 0.1 5.8 6.7 0.0 3.0 3 0 0 3 3 3 0 Leucine rich repeat GIDA PF01134.17 CDO76826.1 - 1.6e-108 363.1 0.0 3.1e-108 362.1 0.0 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 CDO76826.1 - 1.7e-07 31.2 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 GidA associated domain 3 zf-CSL PF05207.8 CDO76827.1 - 3.9e-25 87.1 1.1 3.9e-25 87.1 0.8 1.7 2 0 0 2 2 2 1 CSL zinc finger zinc_ribbon_5 PF13719.1 CDO76827.1 - 0.031 13.8 1.0 0.053 13.1 0.7 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Nop14 PF04147.7 CDO76827.1 - 0.037 11.9 6.7 0.033 12.1 4.6 1.1 1 0 0 1 1 1 0 Nop14-like family Zn-ribbon_8 PF09723.5 CDO76827.1 - 0.046 13.6 0.9 0.095 12.6 0.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain GAGA PF09237.6 CDO76827.1 - 0.095 12.3 0.2 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 GAGA factor zinc_ribbon_4 PF13717.1 CDO76827.1 - 0.12 12.1 1.3 0.2 11.3 0.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain SDA1 PF05285.7 CDO76827.1 - 0.27 10.4 6.6 0.23 10.6 4.5 1.1 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.1 CDO76827.1 - 0.27 10.9 2.2 0.38 10.4 1.5 1.2 1 0 0 1 1 1 0 FAM176 family Paf1 PF03985.8 CDO76827.1 - 0.42 9.2 6.3 0.61 8.7 4.4 1.2 1 0 0 1 1 1 0 Paf1 RXT2_N PF08595.6 CDO76827.1 - 0.61 9.8 3.7 0.84 9.4 2.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal VID27 PF08553.5 CDO76827.1 - 0.71 8.0 4.4 0.67 8.0 3.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2457 PF10446.4 CDO76827.1 - 1.7 7.2 10.2 1.8 7.2 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 CDO76827.1 - 1.9 6.4 5.6 2 6.3 3.9 1.0 1 0 0 1 1 1 0 CDC45-like protein F-box PF00646.28 CDO76828.1 - 1.2e-06 28.0 0.9 6.1e-06 25.7 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CDO76828.1 - 2.5e-05 23.8 0.1 7.6e-05 22.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like Nucleoplasmin PF03066.10 CDO76829.1 - 0.02 14.4 5.6 0.033 13.7 3.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 CDO76829.1 - 0.041 13.0 7.0 0.082 12.0 4.8 1.6 1 0 0 1 1 1 0 Myc amino-terminal region RRN3 PF05327.6 CDO76829.1 - 0.42 8.6 2.3 0.7 7.9 1.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ATHILA PF03078.10 CDO76829.1 - 3.2 6.2 4.8 4.5 5.7 3.4 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family Rad60-SLD PF11976.3 CDO76833.1 - 1.5e-08 34.2 0.3 2.3e-08 33.5 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Solute_trans_a PF03619.11 CDO76835.1 - 3.3e-36 125.0 4.6 4.2e-36 124.6 3.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha adh_short PF00106.20 CDO76840.1 - 5.5e-14 52.4 1.5 5.5e-14 52.4 1.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO76840.1 - 5.6e-07 29.5 0.1 6.6e-07 29.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO76840.1 - 4.5e-05 23.2 1.1 6.8e-05 22.6 0.6 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CDO76840.1 - 0.015 14.9 0.3 0.028 14.0 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 CDO76840.1 - 0.022 14.3 1.1 0.05 13.2 0.1 2.0 2 1 0 2 2 2 0 YjeF-related protein N-terminus DUF1598 PF07643.6 CDO76840.1 - 0.023 14.7 0.3 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) DNA_processg_A PF02481.10 CDO76840.1 - 0.3 9.9 4.2 0.51 9.1 0.1 2.1 2 0 0 2 2 2 0 DNA recombination-mediator protein A PIP5K PF01504.13 CDO76841.1 - 2.3e-56 190.7 0.0 3.8e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DIM1 PF02966.11 CDO76842.1 - 1.2e-68 228.7 0.0 1.3e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CDO76842.1 - 0.0001 21.9 0.0 0.00013 21.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CDO76842.1 - 0.019 15.0 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.1 CDO76842.1 - 0.025 14.6 0.1 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Pro_isomerase PF00160.16 CDO76843.1 - 1.3e-46 158.5 0.1 1.6e-46 158.3 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2470 PF10615.4 CDO76844.1 - 5.5e-10 39.3 0.0 9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 CDO76844.1 - 4e-09 36.3 1.0 7.2e-09 35.4 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4499) 2TM PF13239.1 CDO76844.1 - 0.34 11.0 5.5 0.11 12.5 1.5 1.9 1 1 1 2 2 2 0 2TM domain Cu_amine_oxid PF01179.15 CDO76846.1 - 1.4e-155 518.1 0.0 1.6e-155 517.8 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 CDO76846.1 - 5e-12 45.7 0.0 1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 CDO76846.1 - 4.4e-07 29.8 0.0 9.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Yae1_N PF09811.4 CDO76848.1 - 7.2e-09 35.0 5.9 1.3e-08 34.1 4.1 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal BTB_2 PF02214.17 CDO76848.1 - 0.024 14.8 0.0 0.29 11.3 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain NmrA PF05368.8 CDO76850.1 - 1.1e-32 113.2 0.0 1.4e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CDO76850.1 - 1.3e-07 31.7 0.0 2.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding FGGY_N PF00370.16 CDO76851.1 - 0.0039 16.5 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF463 PF04317.7 CDO76851.1 - 0.094 11.2 0.2 0.28 9.7 0.1 1.6 1 1 1 2 2 2 0 YcjX-like family, DUF463 2OG-FeII_Oxy_2 PF13532.1 CDO76852.1 - 1.5e-26 93.4 0.0 1.9e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acetyltransf_3 PF13302.1 CDO76853.1 - 1.8e-11 44.4 0.0 2.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO76853.1 - 4.2e-05 23.4 0.0 7.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CDO76853.1 - 0.0023 17.8 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Homeobox PF00046.24 CDO76855.1 - 3.1e-06 26.6 0.2 3.1e-06 26.6 0.2 2.0 2 0 0 2 2 2 1 Homeobox domain SLD3 PF08639.5 CDO76856.1 - 3.3e-13 49.1 3.5 9.6e-11 40.9 0.4 2.2 2 0 0 2 2 2 2 DNA replication regulator SLD3 Ank_2 PF12796.2 CDO76857.1 - 2.6e-18 66.1 0.1 3.8e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDO76857.1 - 8.2e-18 63.2 2.1 1.3e-09 37.4 0.2 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CDO76857.1 - 1.8e-17 62.9 0.8 4.6e-09 36.2 0.2 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO76857.1 - 9e-15 53.3 0.1 3.8e-08 32.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CDO76857.1 - 1.9e-14 53.7 0.5 3.1e-05 24.3 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SchA_CurD PF04486.7 CDO76857.1 - 0.071 12.9 0.0 0.19 11.5 0.0 1.6 1 1 1 2 2 2 0 SchA/CurD like domain Sec7_N PF12783.2 CDO76858.1 - 4e-36 123.9 3.1 4.5e-35 120.5 0.2 3.3 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CDO76858.1 - 3.2e-06 26.5 0.0 1.3e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Glyco_transf_15 PF01793.11 CDO76859.1 - 6.7e-141 469.0 11.4 8.3e-141 468.7 7.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NEP PF10167.4 CDO76859.1 - 0.09 12.4 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein SEP PF08059.8 CDO76860.1 - 1.4e-24 86.1 0.0 2.6e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 CDO76860.1 - 4e-18 65.2 0.0 6.1e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 UBX domain UPF0547 PF10571.4 CDO76861.1 - 0.18 11.4 3.5 0.68 9.6 0.2 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 CDO76861.1 - 9.9 5.5 10.8 0.65 9.2 0.5 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Pkinase PF00069.20 CDO76862.1 - 2.8e-16 59.4 0.0 4.4e-16 58.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76862.1 - 3.6e-07 29.5 0.0 4.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Aldedh PF00171.17 CDO76864.1 - 5.3e-24 84.3 1.0 1.2e-17 63.4 0.4 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 CDO76864.1 - 0.004 15.9 0.0 0.043 12.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) ICMT PF04140.9 CDO76865.1 - 1.1e-15 57.6 0.7 1.4e-14 54.0 0.5 2.3 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO76865.1 - 3.5e-11 43.1 3.6 8.8e-11 41.8 1.4 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO76865.1 - 1.9e-07 30.0 0.2 2.5e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1700 PF08006.6 CDO76865.1 - 0.61 9.3 2.6 0.46 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) ICMT PF04140.9 CDO76866.1 - 8.6e-16 57.9 1.5 4.5e-15 55.6 1.0 2.2 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO76866.1 - 7.5e-11 42.0 2.7 2e-09 37.5 1.1 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO76866.1 - 1.3e-06 27.2 0.1 1.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NapE PF06796.6 CDO76866.1 - 0.035 13.3 1.3 0.035 13.3 0.9 2.0 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DUF2700 PF10912.3 CDO76866.1 - 0.065 13.2 0.2 0.45 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2700) HPP PF04982.8 CDO76866.1 - 0.6 9.9 9.0 0.086 12.6 0.8 2.3 2 0 0 2 2 2 0 HPP family Ribosomal_L14 PF00238.14 CDO76867.1 - 1.8e-43 147.1 0.8 2.1e-43 146.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hexokinase_2 PF03727.11 CDO76868.1 - 3.8e-79 265.3 0.0 5.1e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CDO76868.1 - 9.9e-70 234.0 0.0 1.4e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 CDO76868.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain ICMT PF04140.9 CDO76869.1 - 1.5e-15 57.1 2.3 4.2e-14 52.5 0.2 2.5 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO76869.1 - 6.9e-10 38.9 8.4 2.5e-08 33.9 0.9 2.6 3 0 0 3 3 3 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO76869.1 - 6.8e-07 28.1 0.5 1e-06 27.5 0.4 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 CDO76870.1 - 9.9e-15 54.5 0.2 6.4e-14 51.9 0.1 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO76870.1 - 3.5e-10 39.9 1.7 1e-09 38.4 0.8 2.0 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO76870.1 - 6.4e-06 24.9 0.1 8.9e-06 24.4 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CDO76870.1 - 0.067 12.4 0.1 0.096 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ICMT PF04140.9 CDO76871.1 - 1.8e-13 50.4 0.1 4.2e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO76871.1 - 4.5e-12 46.0 1.7 5.8e-11 42.4 0.4 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO76871.1 - 0.017 13.6 0.0 0.029 12.8 0.0 1.3 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 CDO76872.1 - 7.4e-09 35.6 1.0 2.3e-07 30.8 0.2 2.6 1 1 2 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 CDO76872.1 - 2.6e-08 33.9 0.1 2.3e-07 30.9 0.0 2.3 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 CDO76872.1 - 3.4e-06 25.8 0.0 4.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MaoC_dehydrat_N PF13452.1 CDO76874.1 - 6.3e-05 22.7 0.0 8.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase DUF4449 PF14613.1 CDO76875.1 - 5.1e-17 62.2 3.2 3.9e-16 59.4 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF1800 PF08811.6 CDO76875.1 - 0.004 16.1 0.2 0.004 16.1 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1800) DUF1365 PF07103.6 CDO76875.1 - 0.096 11.7 0.0 0.25 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1365) DUF883 PF05957.8 CDO76875.1 - 0.68 10.3 19.4 4.1 7.8 0.1 4.4 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF883) RVT_1 PF00078.22 CDO76876.1 - 3.9e-28 98.2 0.0 6.1e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO76876.1 - 8e-13 48.8 0.0 2.2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO76876.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase FTCD_C PF04961.7 CDO76877.1 - 0.0082 15.5 6.2 0.0082 15.5 4.3 1.8 2 0 0 2 2 2 1 Formiminotransferase-cyclodeaminase RNA_pol PF00940.14 CDO76877.1 - 0.11 10.9 0.1 0.14 10.5 0.1 1.2 1 0 0 1 1 1 0 DNA-dependent RNA polymerase DUF607 PF04678.8 CDO76877.1 - 1.7 8.5 6.0 1.5 8.7 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF607 EHN PF06441.7 CDO76878.1 - 4.6e-34 116.7 0.7 1.2e-33 115.3 0.1 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CDO76878.1 - 4.3e-08 33.3 0.3 1.3e-06 28.4 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO76878.1 - 0.039 13.5 0.0 0.091 12.3 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Homeobox_KN PF05920.6 CDO76879.1 - 8.3e-18 63.8 0.1 2e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CDO76879.1 - 5e-05 22.8 0.0 9.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 CDO76879.1 - 0.13 11.2 0.0 0.34 10.0 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez PSD4 PF07631.6 CDO76880.1 - 0.083 13.2 0.1 0.15 12.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1592) rve PF00665.21 CDO76881.1 - 3.9e-28 97.9 0.0 5.7e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CDO76881.1 - 1.1e-08 34.5 0.0 2.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CDO76881.1 - 5.1e-06 25.9 0.1 8.5e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 CDO76882.1 - 5.8e-58 195.7 0.0 9e-58 195.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SnoaL_2 PF12680.2 CDO76885.1 - 0.089 13.2 0.2 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like domain Tet_JBP PF12851.2 CDO76887.1 - 3.7e-06 26.3 0.0 5.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily COX7B PF05392.6 CDO76888.1 - 0.096 12.2 0.3 0.26 10.9 0.2 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Pkinase PF00069.20 CDO76893.1 - 0.0016 17.6 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Mago_nashi PF02792.9 CDO76894.1 - 2.5e-71 237.9 0.2 3e-71 237.7 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Tim54 PF11711.3 CDO76895.1 - 0.02 13.5 2.6 0.028 13.0 1.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Myc_N PF01056.13 CDO76895.1 - 0.27 10.3 7.8 0.42 9.7 5.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NESP55 PF06390.7 CDO76895.1 - 2.4 7.4 13.5 3.7 6.8 9.4 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) IER PF05760.7 CDO76895.1 - 6.8 6.5 12.3 11 5.8 8.5 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Pkinase PF00069.20 CDO76897.1 - 1.6e-27 96.2 0.0 2e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO76897.1 - 2.3e-10 39.9 0.0 3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDO76897.1 - 0.033 13.9 0.1 0.097 12.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family NACHT PF05729.7 CDO76899.1 - 1.8e-08 34.1 0.0 6.2e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CDO76899.1 - 2.1e-05 24.5 0.5 0.00022 21.2 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CDO76899.1 - 0.00015 21.8 0.0 0.00053 20.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain OTCace_N PF02729.16 CDO76900.1 - 4.8e-46 155.9 0.0 7.1e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 CDO76900.1 - 8.4e-40 136.2 0.0 1.3e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF620 PF04788.7 CDO76900.1 - 0.13 11.4 0.5 0.21 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF620) Glycogen_syn PF05693.8 CDO76901.1 - 0 1093.0 0.0 0 1092.7 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.6 CDO76901.1 - 4.3e-07 29.6 0.1 1.3e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 CDO76901.1 - 1e-06 28.2 0.0 0.00065 19.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CDO76901.1 - 1.3e-06 28.6 0.1 2.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain CBF PF03914.12 CDO76902.1 - 1.6e-31 109.0 0.1 7.5e-31 106.7 0.0 2.2 2 0 0 2 2 2 1 CBF/Mak21 family GMC_oxred_N PF00732.14 CDO76903.1 - 6.4e-49 166.6 0.0 8.3e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO76903.1 - 1.3e-21 77.3 0.1 2.9e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CDO76903.1 - 6.9e-05 21.9 0.1 0.00083 18.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDO76903.1 - 8e-05 21.6 0.1 0.16 10.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 CDO76903.1 - 0.0034 16.3 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 CDO76903.1 - 0.0058 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDO76903.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Redoxin PF08534.5 CDO76904.1 - 2.2e-14 53.2 0.1 3.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CDO76904.1 - 1.9e-06 27.5 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF824 PF05688.6 CDO76904.1 - 0.042 13.4 0.1 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) MRG PF05712.8 CDO76905.1 - 1.5e-51 174.0 0.0 2.2e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 CDO76905.1 - 3.9e-09 36.0 0.4 7e-09 35.2 0.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Rubella_Capsid PF05750.6 CDO76905.1 - 0.029 13.7 4.1 0.052 12.9 2.9 1.3 1 0 0 1 1 1 0 Rubella capsid protein DDE_1 PF03184.14 CDO76906.1 - 4.1e-29 101.2 0.0 6.3e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CDO76906.1 - 4.1e-12 45.7 0.0 1.4e-11 44.0 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 CDO76906.1 - 1.7e-08 33.9 0.0 4.1e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.15 CDO76906.1 - 0.0082 16.0 0.2 0.028 14.3 0.1 2.0 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.1 CDO76906.1 - 0.036 13.7 0.0 0.15 11.7 0.0 2.1 1 0 0 1 1 1 0 Homeodomain-like domain SAP PF02037.22 CDO76906.1 - 0.066 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 SAP domain dCMP_cyt_deam_1 PF00383.17 CDO76906.1 - 0.37 10.4 5.1 11 5.7 0.1 2.8 3 0 0 3 3 3 0 Cytidine and deoxycytidylate deaminase zinc-binding region YdjC PF04794.7 CDO76907.1 - 0.1 12.0 0.6 0.13 11.6 0.4 1.2 1 0 0 1 1 1 0 YdjC-like protein YlqD PF11068.3 CDO76907.1 - 0.1 12.6 14.4 0.15 12.0 9.9 1.2 1 0 0 1 1 1 0 YlqD protein Borrelia_P83 PF05262.6 CDO76907.1 - 0.26 9.5 7.8 0.21 9.8 5.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein IncA PF04156.9 CDO76907.1 - 0.36 10.4 12.6 0.47 10.0 8.7 1.2 1 0 0 1 1 1 0 IncA protein Rpp20 PF12328.3 CDO76907.1 - 0.48 10.0 7.3 0.39 10.3 4.2 1.6 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Caldesmon PF02029.10 CDO76907.1 - 0.55 8.5 15.8 0.69 8.2 10.9 1.1 1 0 0 1 1 1 0 Caldesmon MCPVI PF02993.9 CDO76907.1 - 0.61 10.2 8.1 0.85 9.7 5.6 1.1 1 0 0 1 1 1 0 Minor capsid protein VI CENP-Q PF13094.1 CDO76907.1 - 0.7 9.8 13.0 1.1 9.2 9.0 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ycf1 PF05758.7 CDO76907.1 - 0.9 7.1 4.1 0.76 7.4 2.9 1.0 1 0 0 1 1 1 0 Ycf1 U79_P34 PF03064.11 CDO76907.1 - 1.4 8.3 7.8 1.7 8.1 5.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AAA_13 PF13166.1 CDO76907.1 - 1.7 7.0 9.0 2.1 6.7 6.2 1.1 1 0 0 1 1 1 0 AAA domain ATP11 PF06644.6 CDO76907.1 - 2.2 7.6 10.3 2.9 7.3 7.1 1.1 1 0 0 1 1 1 0 ATP11 protein Zn_clus PF00172.13 CDO76907.1 - 2.7 7.9 16.2 0.73 9.7 8.9 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HAUS6_N PF14661.1 CDO76907.1 - 3.9 6.7 9.2 4.7 6.4 6.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF972 PF06156.8 CDO76907.1 - 4.3 7.7 9.3 7.8 6.8 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) NARP1 PF12569.3 CDO76907.1 - 5.4 5.6 12.1 6.4 5.4 8.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 YqfQ PF14181.1 CDO76907.1 - 9.1 6.2 8.6 13 5.8 5.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein UBN_AB PF14075.1 CDO76908.1 - 0.0017 18.0 0.0 0.0017 18.0 0.0 1.4 2 0 0 2 2 2 1 Ubinuclein conserved middle domain rve PF00665.21 CDO76909.1 - 3e-18 66.0 0.0 9.1e-18 64.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CDO76909.1 - 1.4e-07 31.1 0.0 2.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CDO76909.1 - 0.0099 15.2 0.1 0.033 13.5 0.0 1.9 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger rve PF00665.21 CDO76911.1 - 6e-24 84.4 0.2 2.2e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 CDO76911.1 - 2.5e-09 36.7 0.0 1.3e-08 34.4 0.1 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO76911.1 - 2.6e-09 36.6 0.3 5.4e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 CDO76911.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 CDO76911.1 - 0.0017 17.8 0.0 0.0038 16.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain UBN2_3 PF14244.1 CDO76911.1 - 0.16 11.5 0.0 0.39 10.2 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 CDO76911.1 - 0.86 9.3 2.5 1.8 8.3 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle ENTH PF01417.15 CDO76913.1 - 2.1e-49 166.5 0.2 3.2e-49 165.9 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CDO76913.1 - 3.5e-08 32.4 0.1 6.2e-08 31.6 0.0 1.4 1 1 0 1 1 1 1 ANTH domain UIM PF02809.15 CDO76913.1 - 0.012 15.0 12.4 0.11 12.1 0.6 3.1 3 0 0 3 3 3 0 Ubiquitin interaction motif AAA_13 PF13166.1 CDO76913.1 - 0.016 13.7 5.1 0.0084 14.6 2.2 1.4 2 0 0 2 2 2 0 AAA domain DUF1720 PF08226.6 CDO76913.1 - 0.16 12.0 23.7 0.16 12.0 15.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) FtsX PF02687.16 CDO76914.1 - 0.36 10.5 9.7 0.11 12.3 1.1 2.7 3 0 0 3 3 3 0 FtsX-like permease family DUF4234 PF14018.1 CDO76914.1 - 0.82 9.4 9.0 4.6 7.0 1.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) PVL_ORF50 PF07768.6 CDO76915.1 - 0.032 14.2 5.0 0.12 12.3 0.5 2.4 2 0 0 2 2 2 0 PVL ORF-50-like family Lentiviral_Tat PF02998.9 CDO76915.1 - 4.5 7.1 7.1 0.69 9.7 0.5 2.6 2 1 0 2 2 2 0 Lentiviral Tat protein Cpn60_TCP1 PF00118.19 CDO76916.1 - 6.7e-159 529.5 1.9 7.6e-159 529.4 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peripla_BP_2 PF01497.13 CDO76916.1 - 0.084 11.9 0.2 0.27 10.3 0.0 1.9 2 0 0 2 2 2 0 Periplasmic binding protein MRI PF15325.1 CDO76919.1 - 0.092 13.7 0.3 0.18 12.8 0.2 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection PAS_4 PF08448.5 CDO76919.1 - 0.1 12.6 0.2 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 PAS fold gag_pre-integrs PF13976.1 CDO76920.1 - 2.1e-07 30.5 0.4 3.8e-07 29.6 0.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 CDO76920.1 - 1.5e-06 28.3 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Kinesin PF00225.18 CDO76921.1 - 9e-92 307.3 0.0 1.2e-91 306.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Surfac_D-trimer PF09006.6 CDO76921.1 - 0.00027 20.5 0.2 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 Lung surfactant protein D coiled-coil trimerisation DUF2866 PF11065.3 CDO76921.1 - 0.0058 16.5 2.8 0.22 11.4 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2866) FKBP_N PF01346.13 CDO76921.1 - 0.066 13.2 0.6 0.14 12.2 0.4 1.5 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TPR_2 PF07719.12 CDO76921.1 - 0.12 12.3 0.4 0.33 10.9 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat CENP-F_leu_zip PF10473.4 CDO76922.1 - 5.7e-06 26.2 13.4 5.7e-06 26.2 9.3 7.5 3 1 3 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CDO76922.1 - 0.00047 19.4 4.8 0.00047 19.4 3.3 5.1 2 1 4 6 6 6 2 Reovirus sigma C capsid protein IncA PF04156.9 CDO76922.1 - 0.0017 17.9 92.4 0.013 15.1 11.7 6.4 2 1 5 7 7 7 4 IncA protein Spc7 PF08317.6 CDO76922.1 - 0.0047 15.6 3.0 0.0047 15.6 2.1 5.5 2 1 2 5 5 5 2 Spc7 kinetochore protein Nsp1_C PF05064.8 CDO76922.1 - 0.0082 15.7 3.9 0.0082 15.7 2.7 4.8 4 2 0 5 5 5 1 Nsp1-like C-terminal region SlyX PF04102.7 CDO76922.1 - 0.053 13.9 0.5 0.053 13.9 0.3 8.5 6 3 4 10 10 10 0 SlyX AAA_13 PF13166.1 CDO76922.1 - 0.09 11.2 48.5 3.7 5.8 0.5 5.0 2 1 1 3 3 3 0 AAA domain ADIP PF11559.3 CDO76922.1 - 0.12 12.3 0.2 0.12 12.3 0.1 7.7 4 2 5 9 9 9 0 Afadin- and alpha -actinin-Binding Filament PF00038.16 CDO76922.1 - 0.18 11.2 73.7 0.22 10.9 2.5 6.2 2 1 1 4 4 4 0 Intermediate filament protein DUF4201 PF13870.1 CDO76922.1 - 0.31 10.4 58.7 0.16 11.4 4.8 6.7 2 2 0 5 5 5 0 Domain of unknown function (DUF4201) Occludin_ELL PF07303.8 CDO76922.1 - 0.48 11.1 0.0 0.48 11.1 0.0 5.7 4 2 1 6 6 6 0 Occludin homology domain Fib_alpha PF08702.5 CDO76922.1 - 0.71 9.9 29.3 0.98 9.5 2.9 5.5 4 1 1 6 6 6 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.6 CDO76922.1 - 2.6 7.3 23.5 4.8 6.5 0.1 5.9 6 0 0 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.7 CDO76922.1 - 8.1 6.2 31.8 0.16 11.7 3.1 5.7 3 1 1 5 5 5 0 Protein of unknown function (DUF1664) APG6 PF04111.7 CDO76922.1 - 8.6 5.3 74.3 0.12 11.4 8.4 5.3 2 1 2 5 5 5 0 Autophagy protein Apg6 DUF948 PF06103.6 CDO76922.1 - 9.8 6.1 13.3 1.1 9.1 0.5 4.9 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) LSM PF01423.17 CDO76923.1 - 9e-19 66.7 0.7 1.2e-18 66.4 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CDO76923.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.6 CDO76923.1 - 0.022 13.2 3.7 0.028 12.9 2.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) BPL_C PF02237.12 CDO76923.1 - 0.027 14.1 0.3 0.05 13.3 0.2 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Oxidored_FMN PF00724.15 CDO76924.1 - 4e-37 127.9 0.0 3.3e-34 118.4 0.0 2.5 2 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family 2-Hacid_dh PF00389.25 CDO76925.1 - 5.6e-18 64.6 0.0 7.5e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Melibiase PF02065.13 CDO76926.1 - 6.7e-07 28.3 0.0 0.011 14.4 0.0 2.3 2 1 0 2 2 2 2 Melibiase RCC1 PF00415.13 CDO76928.1 - 1.9e-54 181.6 10.3 2.2e-10 40.5 0.7 7.3 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDO76928.1 - 2.9e-39 131.8 30.0 3.6e-09 35.9 0.2 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat DUF3184 PF11380.3 CDO76928.1 - 0.055 11.4 0.0 0.076 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) HCNGP PF07818.8 CDO76929.1 - 1.9e-26 91.8 0.2 3.6e-26 91.0 0.1 1.4 1 0 0 1 1 1 1 HCNGP-like protein DUF3663 PF12404.3 CDO76930.1 - 0.0036 17.0 0.6 0.012 15.3 0.1 2.1 2 1 0 2 2 2 1 Peptidase SKIP_SNW PF02731.10 CDO76930.1 - 1.1 8.6 5.2 19 4.6 0.1 3.1 3 0 0 3 3 3 0 SKIP/SNW domain Zn_clus PF00172.13 CDO76931.1 - 0.00018 21.3 3.8 0.00018 21.3 2.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mcp5_PH PF12814.2 CDO76932.1 - 2.9e-42 143.4 0.1 5.7e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Myosin_tail_1 PF01576.14 CDO76932.1 - 1.2e-05 23.2 23.5 1.2e-05 23.2 16.3 2.5 3 0 0 3 3 3 1 Myosin tail Reo_sigmaC PF04582.7 CDO76932.1 - 0.061 12.5 4.1 0.26 10.4 1.7 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 CDO76932.1 - 3.1 7.2 37.9 0.035 13.5 16.2 3.0 3 0 0 3 3 3 0 Intermediate filament protein DUF3584 PF12128.3 CDO76932.1 - 4.7 4.4 46.1 0.016 12.6 22.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) WD40 PF00400.27 CDO76934.1 - 1.2e-63 208.8 20.5 2.4e-10 39.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CDO76934.1 - 4.9e-24 84.3 4.7 9.2e-24 83.4 3.3 1.4 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 CDO76934.1 - 0.00051 18.4 1.0 0.026 12.8 0.1 2.9 2 1 0 3 3 3 1 Cytochrome D1 heme domain Nbas_N PF15492.1 CDO76934.1 - 0.0009 18.4 0.0 8.7 5.3 0.0 3.4 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal DUF1777 PF08648.7 CDO76934.1 - 0.0014 18.3 25.2 0.0014 18.3 17.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) Nucleoporin_N PF08801.6 CDO76934.1 - 0.0056 15.4 0.0 3.7 6.2 0.0 3.4 2 1 1 3 3 3 1 Nup133 N terminal like PAT1 PF09770.4 CDO76934.1 - 0.015 13.5 10.1 0.023 12.9 7.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HALZ PF02183.13 CDO76934.1 - 0.017 14.8 0.2 0.095 12.4 0.0 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper PD40 PF07676.7 CDO76934.1 - 0.037 13.6 0.1 32 4.3 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF3450 PF11932.3 CDO76934.1 - 0.039 13.2 2.0 0.068 12.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PSII_BNR PF14870.1 CDO76934.1 - 0.055 12.4 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Proteasome_A_N PF10584.4 CDO76934.1 - 0.11 11.8 2.7 79 2.7 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF3312 PF11768.3 CDO76934.1 - 0.38 8.9 0.0 4.9 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Nup160 PF11715.3 CDO76934.1 - 0.43 8.6 2.7 1.8 6.6 0.0 3.1 2 1 2 4 4 4 0 Nucleoporin Nup120/160 DUF3827 PF12877.2 CDO76934.1 - 2.8 5.9 4.6 5.8 4.8 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MFS_1 PF07690.11 CDO76935.1 - 1.7e-28 99.3 51.5 1.5e-26 92.9 36.1 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO76935.1 - 7.6e-22 77.2 15.3 1.4e-21 76.3 10.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CDO76935.1 - 2.8e-07 29.4 13.7 2.8e-07 29.4 9.5 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter PgaD PF13994.1 CDO76935.1 - 10 5.6 11.1 3.6 7.0 2.4 2.6 2 0 0 2 2 2 0 PgaD-like protein MFS_1 PF07690.11 CDO76936.1 - 3.3e-15 55.6 28.9 4.3e-11 42.1 10.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily NfeD PF01957.13 CDO76936.1 - 8.8 6.4 14.5 0.85 9.7 1.3 3.3 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding p450 PF00067.17 CDO76937.1 - 1e-54 185.7 0.0 2.7e-54 184.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 NAD_kinase PF01513.16 CDO76941.1 - 2e-25 89.1 0.0 6.1e-25 87.5 0.0 1.5 1 1 1 2 2 2 1 ATP-NAD kinase XPG_I_2 PF12813.2 CDO76942.1 - 1.1e-08 34.8 0.0 1.2e-07 31.4 0.0 2.5 3 0 0 3 3 3 1 XPG domain containing PH PF00169.24 CDO76943.1 - 6.2e-05 23.1 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 PH domain BicD PF09730.4 CDO76943.1 - 0.9 7.8 0.7 1.4 7.2 0.5 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D PB1 PF00564.19 CDO76945.1 - 8.3e-12 44.6 0.0 1.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.1 CDO76945.1 - 3.3e-06 26.6 2.3 0.00066 19.2 0.6 3.3 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 CDO76945.1 - 9.9e-05 21.9 4.0 0.43 10.6 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDO76945.1 - 0.0045 16.5 6.3 1.6 8.5 0.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF3354 PF11834.3 CDO76945.1 - 0.15 11.6 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) TPR_8 PF13181.1 CDO76945.1 - 0.45 10.4 2.6 45 4.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L37 PF08561.5 CDO76947.1 - 2.8e-19 68.4 0.4 1.3e-18 66.3 0.1 2.1 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L37 zf-C3HC4_3 PF13920.1 CDO76949.1 - 2.6e-06 27.0 6.7 2.6e-06 27.0 4.7 2.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO76949.1 - 0.011 15.3 8.8 0.011 15.3 6.1 3.5 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Gly-rich_Ago1 PF12764.2 CDO76949.1 - 0.36 11.4 3.5 0.75 10.4 2.4 1.5 1 0 0 1 1 1 0 Glycine-rich region of argonaut ADH_zinc_N PF00107.21 CDO76951.1 - 3.3e-17 62.2 0.0 5.8e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO76951.1 - 3e-06 26.9 0.7 2.3e-05 24.0 0.3 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CDO76951.1 - 3e-05 24.9 0.0 7.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Plant_vir_prot PF01307.12 CDO76951.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Plant viral movement protein DDE_Tnp_4 PF13359.1 CDO76956.1 - 6.3e-23 81.1 0.0 7.8e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 CDO76956.1 - 5.4e-07 29.3 0.0 1.3e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 CDO76956.1 - 0.0052 16.2 0.1 0.0083 15.5 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO76956.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain DUF1179 PF06678.6 CDO76957.1 - 1 9.7 0.0 1 9.7 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1179) CPSF_A PF03178.10 CDO76960.1 - 2.5e-94 315.9 0.0 5.9e-94 314.7 0.0 1.7 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 CDO76960.1 - 3.8e-79 266.1 0.0 6.1e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Topoisom_bac PF01131.15 CDO76960.1 - 1.5e-76 257.8 0.0 1.2e-46 159.4 0.0 2.2 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 CDO76960.1 - 5.9e-22 77.5 0.0 4.3e-21 74.7 0.0 2.4 2 0 0 2 2 2 1 Toprim domain zf-GRF PF06839.7 CDO76960.1 - 1.2e-17 63.5 11.5 1.7e-10 40.6 2.6 2.6 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC PF00098.18 CDO76960.1 - 4.9e-09 35.6 12.8 1.5e-05 24.6 2.1 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CDO76960.1 - 0.001 18.7 3.0 0.14 11.9 0.3 2.7 2 0 0 2 2 2 2 Zinc knuckle p450 PF00067.17 CDO76961.1 - 1.5e-68 231.4 0.0 1.8e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1297 PF06973.7 CDO76961.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) Glyoxal_oxid_N PF07250.6 CDO76962.1 - 9.8e-35 119.7 0.1 8.6e-33 113.3 0.0 3.1 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CDO76962.1 - 8.3e-24 83.5 0.1 1.5e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 CDO76962.1 - 8e-06 25.5 0.1 0.0062 16.2 0.0 3.2 2 0 0 2 2 2 2 Galactose oxidase, central domain AFG1_ATPase PF03969.11 CDO76964.1 - 5.3e-28 97.8 0.0 2.4e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase RHD3 PF05879.7 CDO76965.1 - 6.1e-248 824.5 2.6 3.6e-247 822.0 1.8 1.8 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 CDO76965.1 - 8.3e-08 31.5 0.1 1.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 CDO76965.1 - 4.7e-06 26.5 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CDO76965.1 - 1e-05 25.4 0.0 2.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 CDO76965.1 - 0.00017 22.1 0.0 0.00041 20.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 CDO76965.1 - 0.00083 19.3 0.0 0.0027 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Endonuc-dimeris PF09124.5 CDO76965.1 - 0.0052 16.3 0.5 1.2 8.7 0.0 3.2 3 0 0 3 3 3 1 T4 recombination endonuclease VII, dimerisation Septin PF00735.13 CDO76965.1 - 0.038 13.0 0.0 0.068 12.1 0.0 1.4 1 0 0 1 1 1 0 Septin GerPC PF10737.4 CDO76965.1 - 0.079 12.7 0.4 5.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Spore germination protein GerPC FeoB_N PF02421.13 CDO76965.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B BTB PF00651.26 CDO76966.1 - 2.7e-07 30.5 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain HAD_2 PF13419.1 CDO76967.1 - 1.4e-19 70.9 0.0 2.5e-19 70.1 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDO76967.1 - 1.7e-09 38.4 0.0 5.2e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CDO76967.1 - 0.0015 18.3 0.0 0.52 10.2 0.0 2.6 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CDO76967.1 - 0.0061 16.7 0.0 0.0072 16.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CDO76967.1 - 0.017 14.8 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like BTB PF00651.26 CDO76970.1 - 8.9e-10 38.5 0.3 1.2e-09 38.1 0.2 1.1 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 CDO76970.1 - 0.067 13.2 0.1 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain Kelch_4 PF13418.1 CDO76971.1 - 1.8e-17 62.8 0.2 8e-08 31.9 0.0 5.4 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CDO76971.1 - 2.9e-13 49.4 0.1 0.00011 22.0 0.0 5.3 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.1 CDO76971.1 - 2.3e-11 43.5 1.2 0.0036 17.4 0.0 6.6 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CDO76971.1 - 9e-08 31.9 1.7 1.1 9.5 0.0 5.8 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.20 CDO76971.1 - 7.3e-07 28.6 0.0 0.11 12.0 0.0 4.1 4 1 0 4 4 4 2 Kelch motif Prefoldin_2 PF01920.15 CDO76972.1 - 3.9e-23 81.2 4.5 4.4e-23 81.0 3.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit BLOC1_2 PF10046.4 CDO76972.1 - 0.0038 17.3 3.9 0.01 15.9 0.3 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin PF02996.12 CDO76972.1 - 0.0063 16.1 6.6 0.24 11.0 0.3 2.1 1 1 1 2 2 2 2 Prefoldin subunit ATG16 PF08614.6 CDO76972.1 - 0.011 15.5 1.3 3.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc24 PF08286.6 CDO76972.1 - 0.011 15.4 4.2 1.1 8.9 0.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.7 CDO76972.1 - 0.012 15.7 1.4 2 8.7 0.4 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MIF4G_like_2 PF09090.6 CDO76972.1 - 0.014 14.6 0.7 0.018 14.2 0.5 1.1 1 0 0 1 1 1 0 MIF4G like DUF4140 PF13600.1 CDO76972.1 - 0.014 15.8 2.4 0.6 10.5 0.2 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1049 PF06305.6 CDO76972.1 - 0.028 13.8 0.6 0.97 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) IncA PF04156.9 CDO76972.1 - 0.03 13.9 4.1 0.042 13.4 2.9 1.2 1 0 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 CDO76972.1 - 0.032 13.9 3.6 1.6 8.4 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.6 CDO76972.1 - 0.055 12.1 4.6 0.08 11.5 3.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PspA_IM30 PF04012.7 CDO76972.1 - 0.056 12.8 6.1 0.3 10.3 0.1 2.1 2 0 0 2 2 2 0 PspA/IM30 family DivIC PF04977.10 CDO76972.1 - 0.06 12.8 11.7 0.47 9.9 1.3 2.2 1 1 0 2 2 2 0 Septum formation initiator AAA_23 PF13476.1 CDO76972.1 - 0.068 13.4 3.4 0.084 13.1 2.3 1.2 1 0 0 1 1 1 0 AAA domain PEARLI-4 PF05278.7 CDO76972.1 - 0.079 12.3 0.4 0.079 12.3 0.3 1.6 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) CENP-F_leu_zip PF10473.4 CDO76972.1 - 0.085 12.7 9.1 0.28 11.0 0.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Serine_rich PF08824.5 CDO76972.1 - 0.087 12.5 0.1 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Serine rich protein interaction domain Mo25 PF08569.6 CDO76972.1 - 0.11 11.5 1.3 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Mo25-like Rho_Binding PF08912.6 CDO76972.1 - 0.13 12.5 5.5 0.53 10.6 0.5 2.3 2 0 0 2 2 2 0 Rho Binding DASH_Dad3 PF08656.5 CDO76972.1 - 0.13 11.9 3.9 0.69 9.6 0.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 Macoilin PF09726.4 CDO76972.1 - 0.14 10.4 5.6 0.079 11.2 0.3 1.9 1 1 1 2 2 2 0 Transmembrane protein TBPIP PF07106.8 CDO76972.1 - 0.14 11.7 6.3 1 8.8 0.1 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4404 PF14357.1 CDO76972.1 - 0.16 12.4 2.7 6.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) FTA4 PF13093.1 CDO76972.1 - 0.21 10.9 5.2 0.31 10.4 3.6 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Leu_zip PF15294.1 CDO76972.1 - 0.24 10.4 5.7 0.42 9.6 3.9 1.3 1 1 0 1 1 1 0 Leucine zipper TMF_DNA_bd PF12329.3 CDO76972.1 - 0.28 11.0 8.1 2 8.2 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 CDO76972.1 - 0.28 11.2 4.5 2.2 8.3 0.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2951 PF11166.3 CDO76972.1 - 0.31 10.9 6.6 0.25 11.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DUF2681 PF10883.3 CDO76972.1 - 0.33 11.1 3.4 3.2 7.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TBCA PF02970.11 CDO76972.1 - 0.55 10.3 5.2 6 7.0 0.5 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A DUF972 PF06156.8 CDO76972.1 - 0.71 10.2 3.7 6 7.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF342 PF03961.8 CDO76972.1 - 0.79 8.0 4.4 1.5 7.1 3.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) SlyX PF04102.7 CDO76972.1 - 1.1 9.7 6.2 7.1 7.0 0.2 2.2 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.6 CDO76972.1 - 1.1 9.1 7.1 1.3 9.0 0.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Wbp11 PF09429.5 CDO76972.1 - 1.4 8.9 5.4 7.7 6.5 0.3 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 MerR-DNA-bind PF09278.6 CDO76972.1 - 1.5 9.2 5.3 1.3 9.4 0.2 2.6 2 1 1 3 3 3 0 MerR, DNA binding DUF607 PF04678.8 CDO76972.1 - 1.5 8.7 5.5 1 9.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Mnd1 PF03962.10 CDO76972.1 - 2.3 7.8 7.4 12 5.5 5.1 1.8 1 1 0 1 1 1 0 Mnd1 family bZIP_1 PF00170.16 CDO76972.1 - 4.2 7.4 10.0 1.7 8.6 0.3 2.2 2 0 0 2 2 2 0 bZIP transcription factor FbpA PF05833.6 CDO76972.1 - 4.2 5.7 9.5 0.5 8.8 1.1 2.0 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) Syntaxin PF00804.20 CDO76972.1 - 7.7 6.7 7.8 4.5 7.4 1.3 2.1 1 1 0 2 2 2 0 Syntaxin Mst1_SARAH PF11629.3 CDO76972.1 - 7.9 6.3 8.3 9.6 6.1 1.8 2.9 2 2 1 3 3 3 0 C terminal SARAH domain of Mst1 Pyridoxal_deC PF00282.14 CDO76973.1 - 1.8e-15 56.3 0.0 3.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CDO76973.1 - 2e-07 30.0 0.1 3.6e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CDO76973.1 - 5.1e-06 25.7 0.3 8.8e-06 24.9 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Sugar_tr PF00083.19 CDO76976.1 - 2.1e-48 165.0 18.6 3.3e-48 164.3 12.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO76976.1 - 2.6e-20 72.4 37.6 1.6e-19 69.8 15.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO76979.1 - 1.2e-45 156.0 21.0 2.5e-45 154.9 14.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO76979.1 - 4.9e-14 51.8 32.9 4.9e-14 51.8 22.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SIMPL PF04402.9 CDO76980.1 - 0.13 12.0 0.4 0.19 11.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Glyco_hydro_61 PF03443.9 CDO76981.1 - 0.12 12.2 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 61 Tubulin_C PF03953.12 CDO76984.1 - 4.1e-40 136.7 0.0 7e-40 135.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 CDO76984.1 - 5.8e-38 130.8 1.1 1.7e-36 126.0 0.0 2.4 2 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 CDO76984.1 - 0.018 14.4 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain DUF1479 PF07350.7 CDO76985.1 - 8.7e-137 455.9 0.0 1e-136 455.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 CDO76985.1 - 2.3e-05 24.5 0.0 0.045 13.7 0.0 2.7 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Cyanate_lyase PF02560.9 CDO76986.1 - 4.6e-27 93.3 0.0 8.2e-27 92.5 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Complex1_LYR PF05347.10 CDO76986.1 - 0.00029 20.5 0.0 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CDO76986.1 - 0.00094 19.3 0.0 0.0031 17.6 0.0 1.7 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CDO76986.1 - 0.0025 18.2 0.0 0.004 17.6 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF4604 PF15377.1 CDO76987.1 - 1e-25 90.8 6.6 1.3e-25 90.4 4.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Peptidase_S10 PF00450.17 CDO76988.1 - 5.3e-64 216.8 0.1 3.9e-63 214.0 0.0 2.2 1 1 0 1 1 1 1 Serine carboxypeptidase CIA30 PF08547.7 CDO76991.1 - 3.4e-19 69.2 0.0 2.3e-17 63.2 0.0 2.2 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 CDO76991.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.7 1 1 0 1 1 1 0 Carbohydrate binding domain (family 11) Ras PF00071.17 CDO76993.1 - 5.7e-56 188.3 0.0 6.7e-56 188.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDO76993.1 - 1.5e-19 70.6 0.0 2.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDO76993.1 - 1.7e-09 37.1 0.0 1.9e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CDO76993.1 - 3.4e-07 29.8 0.0 7.1e-07 28.8 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDO76993.1 - 0.0047 16.8 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CDO76993.1 - 0.0071 15.5 0.0 0.0089 15.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 CDO76993.1 - 0.27 10.7 1.5 2.2 7.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_B PF00430.13 CDO76994.1 - 0.068 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2240 PF09999.4 CDO76994.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) IMS PF00817.15 CDO76995.1 - 7.8e-35 119.8 0.0 1.5e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CDO76995.1 - 1.6e-11 44.1 0.0 6.8e-10 38.9 0.0 2.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain NUDIX PF00293.23 CDO76996.1 - 1.4e-15 57.1 0.0 2.4e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TauD PF02668.11 CDO76998.1 - 3.2e-36 125.3 0.0 4.3e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CAS_CSE1 PF03378.10 CDO76999.1 - 6.6e-118 393.7 0.7 9.9e-118 393.1 0.5 1.2 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 CDO76999.1 - 1.7e-81 273.6 0.0 9.8e-75 251.4 0.0 2.6 2 1 1 3 3 3 2 Cse1 IBN_N PF03810.14 CDO76999.1 - 2.7e-15 56.0 0.1 1.9e-14 53.2 0.1 2.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 CDO76999.1 - 2.3e-05 24.6 10.7 0.074 13.3 1.2 5.2 4 1 1 5 5 5 3 HEAT repeats CLASP_N PF12348.3 CDO76999.1 - 0.0013 18.1 1.0 1 8.6 0.1 3.5 3 0 0 3 3 3 2 CLASP N terminal Xpo1 PF08389.7 CDO76999.1 - 0.0041 17.0 0.0 0.3 11.0 0.0 3.8 4 0 0 4 4 4 1 Exportin 1-like protein DUF1678 PF07913.6 CDO76999.1 - 0.14 11.6 0.1 2.2 7.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1678) HEAT PF02985.17 CDO76999.1 - 0.18 11.9 9.1 2.6 8.3 0.1 5.9 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.1 CDO76999.1 - 5.9 7.5 7.4 13 6.4 0.3 5.1 5 0 0 5 5 5 0 HEAT-like repeat Hydrophobin PF01185.13 CDO77000.1 - 3.5e-19 69.0 7.9 4.7e-19 68.6 5.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin MFS_1 PF07690.11 CDO77001.1 - 3.3e-40 137.8 25.4 4.7e-40 137.3 17.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO77001.1 - 5.9e-14 51.5 4.0 5.9e-14 51.5 2.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter YbgT_YccB PF08173.6 CDO77001.1 - 0.0025 17.5 3.2 0.0027 17.4 0.3 2.7 2 0 0 2 2 2 1 Membrane bound YbgT-like protein Telomere_Sde2 PF13019.1 CDO77002.1 - 7.5e-52 175.2 0.5 1.4e-51 174.3 0.0 1.6 2 0 0 2 2 2 1 Telomere stability and silencing GTSE1_N PF15259.1 CDO77002.1 - 1.3 8.9 6.7 0.19 11.7 0.9 2.0 1 1 0 2 2 2 0 G-2 and S-phase expressed 1 DUF1295 PF06966.7 CDO77003.1 - 2.3e-35 121.9 3.3 2.3e-35 121.9 2.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CDO77003.1 - 0.027 14.6 0.2 0.081 13.1 0.0 1.9 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family zf-C2H2_4 PF13894.1 CDO77004.1 - 2.2e-07 30.7 1.7 0.014 15.6 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO77004.1 - 1.4e-06 28.2 1.7 0.038 14.3 0.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CDO77004.1 - 0.008 16.3 0.3 0.061 13.5 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-BED PF02892.10 CDO77004.1 - 0.085 12.6 2.3 4.2 7.1 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 CDO77006.1 - 2.1e-07 30.7 3.0 0.0046 17.2 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO77006.1 - 5.6e-07 29.5 2.6 0.023 15.0 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 CDO77006.1 - 0.0061 16.7 1.4 0.34 11.2 0.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-BED PF02892.10 CDO77006.1 - 0.18 11.6 2.0 4.4 7.1 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger MFS_1 PF07690.11 CDO77007.1 - 2.6e-25 88.9 20.4 2.6e-25 88.9 14.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDO77007.1 - 0.00022 19.7 20.6 0.0046 15.4 5.8 3.4 2 2 2 4 4 4 2 MFS/sugar transport protein IlvN PF07991.7 CDO77008.1 - 5.1e-46 156.0 0.0 1.1e-45 154.9 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 CDO77008.1 - 1e-40 138.9 0.0 1.6e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 CDO77008.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CotJA PF11007.3 CDO77008.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) ThuA PF06283.6 CDO77009.1 - 1.6e-50 171.8 0.0 2.7e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Trehalose utilisation Pro-kuma_activ PF09286.6 CDO77010.1 - 2.2e-45 154.2 0.0 1.1e-44 151.9 0.0 2.1 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO77010.1 - 1.4e-05 24.3 1.7 2.4e-05 23.6 1.2 1.2 1 0 0 1 1 1 1 Subtilase family Pyr_redox_2 PF07992.9 CDO77011.1 - 2.2e-30 106.0 0.0 4.3e-30 105.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 CDO77011.1 - 1.2e-16 60.0 0.1 4.3e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 CDO77011.1 - 2.9e-12 47.0 0.6 1.5e-05 25.1 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDO77011.1 - 3.2e-08 33.8 5.3 4.5e-07 30.1 0.1 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 CDO77011.1 - 5.5e-08 32.9 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 CDO77011.1 - 5e-07 28.9 0.8 0.4 9.5 0.0 3.1 2 1 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Rieske_2 PF13806.1 CDO77011.1 - 5.6e-07 29.2 0.0 1.9e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DAO PF01266.19 CDO77011.1 - 0.0011 17.9 4.2 0.086 11.7 0.1 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CDO77011.1 - 0.0034 17.6 0.1 0.045 13.9 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding HET PF06985.6 CDO77012.1 - 3.8e-19 69.2 9.9 6.9e-16 58.6 2.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ARPC4 PF05856.7 CDO77012.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) HET PF06985.6 CDO77013.1 - 1.5e-22 80.2 7.8 5.8e-20 71.8 0.7 2.6 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) PI3Ka PF00613.15 CDO77014.1 - 1.7e-57 193.6 0.5 2.9e-57 192.8 0.3 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CDO77014.1 - 5.7e-42 143.7 0.0 1.3e-40 139.3 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CDO77014.1 - 2.1e-33 115.1 0.0 1.7e-32 112.1 0.0 2.2 1 1 0 1 1 1 1 Phosphoinositide 3-kinase C2 Aminotran_3 PF00202.16 CDO77015.1 - 1.4e-20 73.4 0.0 2.6e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 CDO77015.1 - 7.7e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain UQ_con PF00179.21 CDO77016.1 - 1.5e-17 63.3 0.0 2.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SDA1 PF05285.7 CDO77016.1 - 3.4 6.8 7.1 6.6 5.9 4.9 1.4 1 0 0 1 1 1 0 SDA1 DUF3661 PF12400.3 CDO77017.1 - 1.6e-36 125.2 5.8 2.4e-36 124.6 4.0 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein Uds1 PF15456.1 CDO77018.1 - 2.2e-36 124.5 9.6 2.2e-36 124.5 6.6 6.8 3 2 3 6 6 6 1 Up-regulated During Septation CorA PF01544.13 CDO77019.1 - 2.5e-46 158.0 0.7 3.6e-46 157.5 0.5 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 CDO77019.1 - 0.027 14.3 0.5 0.058 13.2 0.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACT_4 PF13291.1 CDO77019.1 - 0.13 12.5 0.2 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 ACT domain DUF3826 PF12875.2 CDO77019.1 - 0.16 11.6 0.3 1.7 8.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) PLU-1 PF08429.6 CDO77020.1 - 3e-52 177.5 1.9 7.9e-52 176.2 1.0 1.8 1 1 1 2 2 2 1 PLU-1-like protein JmjC PF02373.17 CDO77020.1 - 3.7e-41 139.9 0.6 1.1e-40 138.4 0.2 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.11 CDO77020.1 - 8.8e-16 57.7 9.7 8.8e-16 57.7 6.8 2.4 2 0 0 2 2 2 1 C5HC2 zinc finger JmjN PF02375.12 CDO77020.1 - 2.6e-15 55.6 0.2 5.1e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 jmjN domain ARID PF01388.16 CDO77020.1 - 1.2e-11 44.3 0.0 4.9e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 CDO77020.1 - 4.8e-10 38.9 47.3 1.4e-08 34.2 5.5 5.0 5 0 0 5 5 5 3 PHD-finger 14-3-3 PF00244.15 CDO77021.1 - 6e-118 392.1 5.4 6.9e-118 391.9 3.7 1.0 1 0 0 1 1 1 1 14-3-3 protein HisKA PF00512.20 CDO77021.1 - 0.045 13.7 0.7 1.9 8.5 0.1 2.8 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF837 PF05769.6 CDO77021.1 - 0.081 12.4 4.7 1.1 8.7 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) TPR_19 PF14559.1 CDO77021.1 - 0.29 11.5 3.3 2.4 8.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C PF00271.26 CDO77023.1 - 1.2e-05 25.0 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_S28 PF05577.7 CDO77024.1 - 6.9e-51 173.1 0.7 3.1e-36 124.8 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CDO77024.1 - 2.2e-05 24.4 0.0 3.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CDO77024.1 - 0.0041 16.3 0.0 0.0075 15.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.6 CDO77024.1 - 0.066 11.6 0.4 0.17 10.3 0.0 1.7 2 0 0 2 2 2 0 PS-10 peptidase S37 RRM_1 PF00076.17 CDO77027.1 - 2.2e-08 33.6 0.0 3.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO77027.1 - 8e-06 25.7 0.0 1.8e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO77027.1 - 0.002 17.9 0.0 0.0046 16.7 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO77027.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SKG6 PF08693.5 CDO77028.1 - 0.00015 20.9 1.0 0.00028 20.1 0.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 CDO77028.1 - 0.00019 20.9 1.6 0.00031 20.2 1.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 CDO77028.1 - 0.0069 14.7 0.1 0.011 13.9 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 CDO77028.1 - 0.029 14.5 0.6 0.072 13.2 0.4 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Syndecan PF01034.15 CDO77028.1 - 0.094 12.3 0.4 0.16 11.6 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain DAP10 PF07213.6 CDO77028.1 - 0.18 11.5 1.3 0.35 10.6 0.9 1.4 1 0 0 1 1 1 0 DAP10 membrane protein BcrAD_BadFG PF01869.15 CDO77029.1 - 8.7e-13 48.1 0.0 1.3e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Cupin_2 PF07883.6 CDO77030.1 - 9.6e-26 89.0 0.2 6.3e-15 54.4 0.1 2.6 2 1 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 CDO77030.1 - 6.2e-25 87.3 0.1 7.7e-15 54.5 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 CDO77030.1 - 1.5e-06 27.5 0.0 0.0023 17.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 CDO77030.1 - 2.2e-06 27.3 0.0 7.3e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.14 CDO77030.1 - 6.4e-05 22.6 1.2 0.26 10.9 0.0 2.8 2 1 0 2 2 2 2 AraC-like ligand binding domain Cupin_4 PF08007.7 CDO77030.1 - 6.8e-05 22.2 0.0 0.1 11.7 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_8 PF13621.1 CDO77030.1 - 0.00065 19.2 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Cupin-like domain ARD PF03079.9 CDO77030.1 - 0.039 13.9 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 ARD/ARD' family FdtA PF05523.6 CDO77030.1 - 0.16 11.4 0.0 4 6.9 0.0 2.1 2 0 0 2 2 2 0 WxcM-like, C-terminal Cupin_2 PF07883.6 CDO77031.1 - 4e-08 32.6 0.3 7.4e-08 31.7 0.2 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 CDO77031.1 - 5.8e-06 25.7 0.0 8.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 CDO77031.1 - 4.2e-05 23.2 0.2 5e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 CDO77031.1 - 0.00031 20.4 0.3 0.00041 20.0 0.2 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain MFS_1 PF07690.11 CDO77032.1 - 6.5e-30 104.0 27.4 6.5e-30 104.0 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1156 PF06634.7 CDO77032.1 - 0.11 12.2 0.3 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1156) ESSS PF10183.4 CDO77032.1 - 0.13 12.7 0.3 0.46 10.9 0.2 1.9 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) 2-Hacid_dh_C PF02826.14 CDO77033.1 - 7e-52 175.1 0.0 9.4e-52 174.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CDO77033.1 - 1.2e-19 70.1 0.0 1.9e-19 69.4 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CDO77033.1 - 0.00059 19.7 0.0 0.00092 19.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 CDO77033.1 - 0.03 14.6 0.0 0.084 13.1 0.0 1.8 1 1 0 1 1 1 0 XdhC Rossmann domain IlvN PF07991.7 CDO77033.1 - 0.03 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F-box-like PF12937.2 CDO77034.1 - 5.6e-05 22.7 0.4 5.6e-05 22.7 0.3 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDO77034.1 - 0.0015 18.1 1.8 0.0015 18.1 1.2 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CDO77035.1 - 7.7e-08 31.9 0.2 1.8e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO77035.1 - 1.8e-05 24.2 1.0 4.3e-05 23.0 0.7 1.6 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.2 CDO77036.1 - 0.00065 19.9 0.0 0.015 15.6 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDO77036.1 - 0.00075 19.9 0.2 0.18 12.3 0.0 4.2 2 1 4 6 6 6 2 Ankyrin repeats (many copies) SAP PF02037.22 CDO77036.1 - 0.0095 15.4 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 SAP domain Dimer_Tnp_hAT PF05699.9 CDO77036.1 - 0.012 15.2 8.4 0.92 9.1 0.0 4.5 4 1 1 5 5 5 0 hAT family C-terminal dimerisation region DUF4014 PF13198.1 CDO77036.1 - 0.2 12.0 0.6 0.39 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) Sel1 PF08238.7 CDO77037.1 - 1.2e-24 86.1 44.5 4.1e-06 27.2 0.1 11.1 11 1 0 11 11 11 5 Sel1 repeat TPR_12 PF13424.1 CDO77037.1 - 0.00046 20.0 2.1 0.016 15.1 0.1 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDO77037.1 - 0.001 19.6 2.1 0.001 19.6 1.5 6.3 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDO77037.1 - 0.029 14.2 0.5 0.029 14.2 0.4 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDO77037.1 - 0.068 13.6 10.3 20 5.9 0.1 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 CDO77037.1 - 0.27 10.8 15.9 0.12 12.0 1.5 4.0 4 0 0 4 4 4 0 TPR repeat Helicase_C PF00271.26 CDO77038.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3872 PF12988.2 CDO77038.1 - 0.052 13.0 0.0 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3872) PPTA PF01239.17 CDO77039.1 - 1.4e-10 40.0 10.9 8.3e-06 24.9 0.0 5.1 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat ASFV_J13L PF05568.6 CDO77041.1 - 0.16 11.4 3.4 0.32 10.5 2.3 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein SWIB PF02201.13 CDO77043.1 - 3.3e-26 90.7 1.2 5.9e-26 89.9 0.8 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 CDO77043.1 - 0.0005 19.7 0.3 0.0019 17.9 0.2 2.0 2 0 0 2 2 2 1 DEK C terminal domain ATP11 PF06644.6 CDO77043.1 - 0.031 13.7 2.0 0.048 13.1 1.4 1.2 1 0 0 1 1 1 0 ATP11 protein Glypican PF01153.14 CDO77043.1 - 0.04 12.5 3.0 0.052 12.1 2.0 1.1 1 0 0 1 1 1 0 Glypican DUF1053 PF06327.9 CDO77043.1 - 1.4 9.2 5.9 6.4 7.1 0.1 2.7 3 1 1 4 4 4 0 Domain of Unknown Function (DUF1053) RNase_T PF00929.19 CDO77045.1 - 1.1e-19 71.3 0.0 1.2e-19 71.1 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Fcf1 PF04900.7 CDO77047.1 - 1e-40 137.8 0.8 1e-40 137.8 0.6 1.6 2 0 0 2 2 2 1 Fcf1 Lyase_aromatic PF00221.14 CDO77048.1 - 3.7e-161 536.7 3.1 4.9e-161 536.3 2.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase CPSase_L_D2 PF02786.12 CDO77049.1 - 9.1e-108 358.3 0.0 4.4e-83 277.7 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 CDO77049.1 - 1.9e-40 137.4 0.7 3.7e-40 136.5 0.5 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 CDO77049.1 - 7.3e-36 122.6 0.0 3.7e-18 65.6 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 CDO77049.1 - 7.6e-36 123.5 0.1 6.3e-18 65.1 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CDO77049.1 - 7.8e-20 70.8 0.0 3.7e-08 32.4 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CDO77049.1 - 2.6e-16 59.4 0.0 1.5e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CDO77049.1 - 4.1e-12 45.9 0.0 0.00011 21.6 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 CDO77049.1 - 2e-08 33.9 0.0 0.0053 16.2 0.0 3.0 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 CDO77049.1 - 7.4e-06 25.3 0.0 0.025 13.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 CDO77049.1 - 0.0012 18.6 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.17 CDO77049.1 - 0.021 14.7 0.0 0.2 11.5 0.0 2.7 2 0 0 2 2 2 0 MGS-like domain Epimerase PF01370.16 CDO77049.1 - 0.061 12.7 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DAO PF01266.19 CDO77050.1 - 8.5e-53 179.5 0.0 9.9e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDO77050.1 - 2.4e-07 30.6 0.0 5.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CDO77050.1 - 1.8e-05 25.0 0.0 0.00038 20.8 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDO77050.1 - 3e-05 24.1 0.0 0.00035 20.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CDO77050.1 - 3.5e-05 23.0 0.0 0.026 13.6 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 CDO77050.1 - 0.00016 20.6 0.0 0.004 16.0 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CDO77050.1 - 0.00032 20.6 0.0 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CDO77050.1 - 0.00082 18.3 0.0 0.18 10.6 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 CDO77050.1 - 0.0013 17.6 0.0 0.34 9.7 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Shikimate_DH PF01488.15 CDO77050.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 CDO77050.1 - 0.0019 16.7 0.0 0.53 8.6 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein ThiF PF00899.16 CDO77050.1 - 0.0031 17.3 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_9 PF13454.1 CDO77050.1 - 0.0036 17.0 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.13 CDO77050.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 CDO77050.1 - 0.012 14.7 0.0 0.06 12.4 0.0 1.9 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 CDO77050.1 - 0.021 13.8 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.1 CDO77050.1 - 0.032 13.1 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 CDO77050.1 - 0.034 14.3 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 CDO77050.1 - 0.037 13.4 0.2 0.076 12.3 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 CDO77050.1 - 0.04 12.5 0.0 3.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 CDO77050.1 - 0.041 13.5 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 CDO77050.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UPF0052 PF01933.13 CDO77050.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Saccharop_dh PF03435.13 CDO77050.1 - 0.13 11.1 0.1 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase P5CR_dimer PF14748.1 CDO77050.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation ABC_tran PF00005.22 CDO77052.1 - 2.1e-50 170.5 0.1 1.8e-24 86.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 CDO77052.1 - 2.1e-20 72.3 2.8 2.1e-20 72.3 2.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 CDO77052.1 - 1.6e-19 70.9 0.9 0.00029 20.9 0.0 4.4 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 CDO77052.1 - 1.8e-09 37.0 0.5 0.00043 19.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CDO77052.1 - 3.1e-09 36.4 4.1 0.15 11.2 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CDO77052.1 - 7.1e-09 36.2 8.2 0.00057 20.2 0.0 3.9 5 0 0 5 5 3 2 AAA domain AAA_17 PF13207.1 CDO77052.1 - 1.5e-07 32.2 0.3 0.062 14.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 CDO77052.1 - 2.1e-07 30.3 4.8 0.29 10.1 0.0 4.7 3 1 0 4 4 4 3 AAA ATPase domain AAA_16 PF13191.1 CDO77052.1 - 4.4e-07 30.0 0.3 0.0044 17.0 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CDO77052.1 - 3e-06 27.3 0.1 0.16 12.1 0.0 3.5 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 CDO77052.1 - 3.4e-06 26.3 0.0 0.0012 18.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 CDO77052.1 - 3.4e-06 26.8 0.0 0.056 13.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 CDO77052.1 - 3.7e-06 27.4 0.0 0.11 12.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 CDO77052.1 - 9.4e-06 25.1 0.0 0.5 9.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 CDO77052.1 - 1.1e-05 25.3 0.0 0.011 15.7 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 CDO77052.1 - 1.8e-05 24.3 0.1 0.31 10.4 0.0 3.4 3 0 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 CDO77052.1 - 5.4e-05 23.5 0.1 0.28 11.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 CDO77052.1 - 7.9e-05 22.2 0.0 0.59 9.5 0.0 2.8 3 0 0 3 3 2 2 FtsK/SpoIIIE family RNA_helicase PF00910.17 CDO77052.1 - 9.8e-05 22.4 1.8 1.8 8.7 0.0 3.6 3 0 0 3 3 3 1 RNA helicase Dynamin_N PF00350.18 CDO77052.1 - 0.00022 21.0 7.7 0.041 13.6 0.3 4.0 2 2 1 3 3 3 2 Dynamin family MobB PF03205.9 CDO77052.1 - 0.00058 19.5 1.3 0.42 10.3 0.1 3.5 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 CDO77052.1 - 0.0013 18.6 0.0 0.63 9.9 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 CDO77052.1 - 0.0032 17.3 0.0 13 5.7 0.0 4.4 5 0 0 5 5 5 0 AAA domain KAP_NTPase PF07693.9 CDO77052.1 - 0.0034 16.4 0.4 1.1 8.1 0.0 2.8 2 1 0 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.1 CDO77052.1 - 0.0035 16.9 0.1 0.32 10.5 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CDO77052.1 - 0.0068 16.1 0.1 4.3 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CDO77052.1 - 0.008 16.0 0.0 5.4 6.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain Septin PF00735.13 CDO77052.1 - 0.0083 15.1 0.2 2.8 6.8 0.0 3.1 3 0 0 3 3 3 1 Septin AAA_28 PF13521.1 CDO77052.1 - 0.0088 16.0 0.0 0.79 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 CDO77052.1 - 0.0093 15.8 4.7 1.1 9.0 0.0 3.6 4 1 1 5 5 3 1 Domain of unknown function DUF87 FeoB_N PF02421.13 CDO77052.1 - 0.0097 15.1 0.0 0.057 12.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA PF00004.24 CDO77052.1 - 0.01 16.0 0.1 7.7 6.7 0.1 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 CDO77052.1 - 0.017 14.8 0.5 2.6 7.7 0.1 3.1 3 0 0 3 3 2 0 NTPase ATP-synt_ab PF00006.20 CDO77052.1 - 0.018 14.5 0.5 1.7 8.0 0.0 2.7 3 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.15 CDO77052.1 - 0.028 13.1 0.2 1.7 7.2 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit T2SE PF00437.15 CDO77052.1 - 0.029 13.2 0.0 0.75 8.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DAP3 PF10236.4 CDO77052.1 - 0.033 13.1 1.8 3.7 6.4 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 CDO77052.1 - 0.037 12.8 0.0 9.2 5.0 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain cobW PF02492.14 CDO77052.1 - 0.075 12.4 0.1 17 4.8 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 CDO77052.1 - 0.076 11.4 3.6 1.5 7.2 0.0 3.3 4 0 0 4 4 4 0 AAA domain DivIC PF04977.10 CDO77052.1 - 0.18 11.3 5.0 6 6.4 0.8 2.6 2 0 0 2 2 2 0 Septum formation initiator Pox_A32 PF04665.7 CDO77052.1 - 0.47 9.7 5.1 10 5.3 0.0 3.4 3 1 0 3 3 3 0 Poxvirus A32 protein adh_short PF00106.20 CDO77053.1 - 3.1e-24 85.7 0.1 4.1e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO77053.1 - 1.7e-10 41.0 0.0 2.4e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDO77053.1 - 4.2e-07 29.8 0.0 6.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CDO77053.1 - 0.00013 21.6 0.7 0.0014 18.3 0.2 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CDO77053.1 - 0.0023 17.4 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CDO77053.1 - 0.028 14.4 0.8 0.047 13.7 0.6 1.4 1 1 0 1 1 1 0 NADH(P)-binding Arrestin_N PF00339.24 CDO77054.1 - 1.3e-10 41.2 0.0 2.7e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 CDO77054.1 - 0.24 10.4 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Rgp1 MULE PF10551.4 CDO77058.1 - 7.2e-09 35.7 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF1668 PF07893.8 CDO77058.1 - 0.017 14.2 0.1 0.034 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) Zn-ribbon_8 PF09723.5 CDO77058.1 - 0.069 13.1 1.9 6.7 6.7 0.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain CBM_X PF06204.6 CDO77059.1 - 0.023 14.1 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative carbohydrate binding domain AMP-binding PF00501.23 CDO77060.1 - 9.2e-19 67.1 0.0 1.9e-16 59.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.8 CDO77060.1 - 0.0006 18.4 0.1 0.001 17.7 0.1 1.2 1 0 0 1 1 1 1 GH3 auxin-responsive promoter PDEase_I PF00233.14 CDO77061.1 - 2.1e-36 125.8 0.0 3.1e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Peptidase_M28 PF04389.12 CDO77065.1 - 7.3e-24 84.4 0.2 1.8e-23 83.1 0.2 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CDO77065.1 - 6.4e-06 25.7 0.1 8.6e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CDO77065.1 - 0.026 13.2 0.0 0.043 12.5 0.0 1.4 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase MR_MLE_C PF13378.1 CDO77066.1 - 4.6e-17 62.0 0.0 8.2e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 CDO77066.1 - 2.9e-12 46.9 0.1 1.1e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 CDO77066.1 - 3.8e-08 33.3 0.0 9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Abhydrolase_6 PF12697.2 CDO77067.1 - 6.6e-21 75.2 2.5 6.6e-21 75.2 1.7 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO77067.1 - 3.9e-09 36.4 0.1 3.2e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO77067.1 - 2e-05 24.2 0.0 5.4e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold F-box-like PF12937.2 CDO77068.1 - 5.2e-11 42.1 1.0 1.7e-10 40.4 0.7 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 CDO77068.1 - 0.071 12.7 3.1 0.28 10.8 0.2 3.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) HET PF06985.6 CDO77069.1 - 8.6e-11 42.1 0.0 1.6e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bud13 PF09736.4 CDO77070.1 - 1.8e-47 161.2 7.4 1.8e-47 161.2 5.1 2.7 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex NYD-SP12_N PF15015.1 CDO77070.1 - 3.4 5.7 8.1 5.2 5.1 5.6 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Sec23_trunk PF04811.10 CDO77071.1 - 4.8e-49 166.9 0.0 7.7e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CDO77071.1 - 8.5e-19 67.8 0.0 1.6e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CDO77071.1 - 7.9e-16 57.3 4.1 1.5e-15 56.4 2.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 CDO77071.1 - 1.9e-12 46.5 0.1 3.6e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 CDO77071.1 - 0.031 13.9 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 Gelsolin repeat Kinetocho_Slk19 PF12709.2 CDO77072.1 - 0.017 15.1 4.8 0.017 15.1 3.3 2.3 1 1 1 2 2 2 0 Central kinetochore-associated APG6 PF04111.7 CDO77072.1 - 0.26 10.2 14.2 0.38 9.7 9.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Sec34 PF04136.10 CDO77072.1 - 0.32 10.6 2.0 0.5 10.0 1.4 1.3 1 0 0 1 1 1 0 Sec34-like family Borrelia_REV PF03978.8 CDO77072.1 - 0.59 9.8 2.5 0.33 10.6 0.4 1.6 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein DUF3584 PF12128.3 CDO77072.1 - 1 6.6 16.8 1.4 6.1 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) bZIP_1 PF00170.16 CDO77072.1 - 1.1 9.2 17.9 4.1 7.4 0.0 3.6 2 1 1 3 3 3 0 bZIP transcription factor TMF_DNA_bd PF12329.3 CDO77072.1 - 1.4 8.7 13.3 1.3 8.8 0.1 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 CDO77072.1 - 2.1 6.6 7.2 2.8 6.2 5.0 1.0 1 0 0 1 1 1 0 AAA domain DUF812 PF05667.6 CDO77072.1 - 2.7 6.3 13.5 4.6 5.6 9.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.3 CDO77072.1 - 3.6 7.3 18.3 0.12 12.0 5.4 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.6 CDO77072.1 - 4 6.0 12.3 5.6 5.5 8.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 CDO77072.1 - 4.8 6.6 10.3 1.9 8.0 4.1 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PEP-utilisers_N PF05524.8 CDO77072.1 - 4.9 6.9 13.6 0.38 10.5 3.0 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DSPc PF00782.15 CDO77073.1 - 9.5e-28 96.4 0.0 1.4e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDO77073.1 - 0.00079 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UreD PF01774.12 CDO77074.1 - 7.7e-50 169.2 0.1 1e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein Ribosomal_L24e PF01246.15 CDO77074.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L24e RNA_pol_L_2 PF13656.1 CDO77075.1 - 4.2e-13 48.5 0.0 5.1e-12 45.0 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CDO77075.1 - 5.1e-07 28.7 0.0 1.1e-05 24.4 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NMO PF03060.10 CDO77077.1 - 2.5e-42 145.2 0.2 4e-28 98.5 0.1 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 CDO77077.1 - 3.5e-05 22.8 0.2 0.00011 21.2 0.1 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CDO77077.1 - 0.012 14.5 0.1 0.02 13.7 0.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF1902 PF08972.6 CDO77077.1 - 0.081 12.4 0.1 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) LPAM_2 PF13627.1 CDO77077.1 - 6.6 6.5 6.5 19 5.1 4.5 1.8 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Formyl_trans_N PF00551.14 CDO77078.1 - 4.3e-22 78.5 0.0 6.3e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 CDO77078.1 - 5.6e-10 39.2 0.0 8.6e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MutS_V PF00488.16 CDO77079.1 - 1.5e-53 181.6 0.0 3.4e-45 154.2 0.0 2.3 1 1 1 2 2 2 2 MutS domain V MutS_I PF01624.15 CDO77079.1 - 4.2e-34 116.9 0.2 8.6e-34 115.9 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 CDO77079.1 - 3.8e-23 82.3 0.1 1.9e-17 63.7 0.0 2.5 1 1 1 2 2 2 2 MutS domain III MutS_II PF05188.12 CDO77079.1 - 2.5e-12 47.0 0.0 8.7e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CDO77079.1 - 3.9e-10 39.7 0.4 8.6e-10 38.6 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV DUF3415 PF11895.3 CDO77080.1 - 3.8e-38 129.2 3.0 8.2e-38 128.1 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 CDO77080.1 - 6.2e-28 97.8 0.0 9.6e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Pkinase PF00069.20 CDO77081.1 - 5.8e-49 166.5 0.0 7.3e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77081.1 - 1.9e-22 79.5 0.0 2.8e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO77081.1 - 9.6e-11 41.1 0.0 1.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDO77081.1 - 0.00012 21.2 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDO77081.1 - 0.0076 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PH_3 PF14593.1 CDO77081.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 PH domain HYLS1_C PF15311.1 CDO77081.1 - 0.048 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus Nup96 PF12110.3 CDO77082.1 - 1.6e-75 253.8 0.0 2.7e-75 253.1 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 CDC45 PF02724.9 CDO77082.1 - 1.4 6.8 7.9 2.1 6.3 5.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CDO77082.1 - 7 4.4 14.2 9.7 3.9 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family CLTH PF10607.4 CDO77084.1 - 1e-31 109.5 0.1 1.7e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Transp_cyt_pur PF02133.10 CDO77085.1 - 8.5e-120 400.2 41.5 1.5e-118 396.1 28.8 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2263 PF10021.4 CDO77086.1 - 1.7e-19 70.2 0.1 9.5e-19 67.8 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) 6PF2K PF01591.13 CDO77087.1 - 3e-46 157.2 0.0 5.4e-26 91.0 0.0 2.2 1 1 1 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CDO77087.1 - 5.1e-26 91.6 0.1 1e-25 90.6 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CDO77087.1 - 2e-05 24.4 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDO77087.1 - 0.00093 20.0 0.5 0.0033 18.2 0.0 2.2 3 1 0 3 3 3 1 AAA domain KTI12 PF08433.5 CDO77087.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 CDO77087.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RRM_1 PF00076.17 CDO77088.1 - 5.1e-10 38.8 0.1 1.3e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO77088.1 - 3.2e-06 27.0 0.3 7.1e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CDO77088.1 - 7.5e-06 26.3 0.9 1.6e-05 25.2 0.6 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 CDO77088.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 CDO77089.1 - 2.5e-12 46.1 32.3 6.6e-07 28.3 3.8 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CDO77089.1 - 0.048 13.6 2.4 6.9 6.7 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 CDO77090.1 - 1.6e-20 73.1 24.7 1.6e-20 73.1 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CDO77090.1 - 0.0052 16.7 1.1 0.0052 16.7 0.7 4.3 4 0 0 4 4 4 2 Protein of unknown function (DUF1228) MFS_1 PF07690.11 CDO77091.1 - 1.7e-23 82.9 35.7 4.1e-18 65.2 5.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CDO77091.1 - 0.00012 21.9 8.9 0.00017 21.5 0.1 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1228) HLH PF00010.21 CDO77093.1 - 1.1e-08 34.6 0.0 3.3e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4192 PF13830.1 CDO77094.1 - 0.25 10.9 1.9 0.35 10.4 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) NARP1 PF12569.3 CDO77094.1 - 0.53 8.9 5.5 0.7 8.5 3.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3043 PF11241.3 CDO77094.1 - 0.85 9.1 13.2 1.8 8.0 9.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) RR_TM4-6 PF06459.7 CDO77094.1 - 1.8 8.3 8.2 0.42 10.4 2.3 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 CDO77094.1 - 3 6.3 8.4 0.42 9.1 2.9 1.6 1 1 1 2 2 2 0 Inner membrane protein import complex subunit Tim54 YqfQ PF14181.1 CDO77094.1 - 7.2 6.6 11.4 1.3 9.0 4.8 1.9 2 0 0 2 2 2 0 YqfQ-like protein MMR_HSR1 PF01926.18 CDO77095.1 - 7.4e-10 38.8 0.0 1.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CDO77095.1 - 0.0054 16.7 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.13 CDO77095.1 - 0.0066 15.7 0.3 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.1 CDO77095.1 - 0.013 15.7 0.8 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CDO77095.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.18 CDO77095.1 - 0.035 12.9 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family AAA_17 PF13207.1 CDO77095.1 - 0.047 14.5 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 CDO77095.1 - 0.073 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 CDO77095.1 - 0.074 12.5 0.9 0.097 12.1 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 CDO77095.1 - 0.096 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Arf PF00025.16 CDO77095.1 - 0.19 10.9 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Exo_endo_phos_2 PF14529.1 CDO77096.1 - 7.8e-08 31.9 0.0 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-CCHC_6 PF15288.1 CDO77096.1 - 0.014 15.0 1.4 0.035 13.7 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle ERM PF00769.14 CDO77096.1 - 0.037 13.5 2.8 0.07 12.6 2.0 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Laminin_II PF06009.7 CDO77096.1 - 0.087 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Laminin Domain II CHD5 PF04420.9 CDO77097.1 - 3.5e-47 160.0 0.9 4.2e-47 159.7 0.6 1.1 1 0 0 1 1 1 1 CHD5-like protein MotB_plug PF13677.1 CDO77097.1 - 2.8 7.3 5.2 5.6 6.3 3.6 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Malate_synthase PF01274.17 CDO77098.1 - 2.6e-199 662.5 0.0 3.2e-199 662.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Pkinase PF00069.20 CDO77099.1 - 8.9e-24 84.0 0.0 3.8e-17 62.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77099.1 - 4.1e-16 58.8 0.0 7.1e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CDO77099.1 - 0.0035 16.4 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CDO77099.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Smr PF01713.16 CDO77100.1 - 1.1e-09 38.2 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Smr domain HlyIII PF03006.15 CDO77101.1 - 6.5e-37 127.0 21.0 9.4e-37 126.5 14.0 1.7 2 0 0 2 2 2 1 Haemolysin-III related DUF1129 PF06570.6 CDO77101.1 - 0.032 13.5 1.0 0.054 12.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) F-box PF00646.28 CDO77102.1 - 7e-07 28.7 0.4 2e-06 27.2 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO77102.1 - 0.0003 20.4 0.3 0.00078 19.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like TFIID_20kDa PF03847.8 CDO77103.1 - 4e-29 100.6 0.5 6.5e-29 100.0 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 CDO77103.1 - 0.00083 19.3 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Rep_4 PF05797.6 CDO77103.1 - 0.097 11.3 0.9 0.15 10.6 0.6 1.3 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) BiPBP_C PF06832.7 CDO77103.1 - 0.77 9.7 4.4 8.1 6.4 0.0 3.0 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family Afaf PF15339.1 CDO77104.1 - 0.16 11.5 0.0 0.16 11.5 0.0 2.1 3 0 0 3 3 3 0 Acrosome formation-associated factor RNase_H PF00075.19 CDO77106.1 - 0.014 15.7 0.0 0.054 13.8 0.0 1.9 1 1 0 1 1 1 0 RNase H DUF4588 PF15251.1 CDO77108.1 - 5.6e-05 23.2 4.0 0.00016 21.7 2.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) MCPVI PF02993.9 CDO77108.1 - 0.0011 19.2 7.8 0.016 15.3 3.5 2.2 1 1 1 2 2 2 2 Minor capsid protein VI DUF605 PF04652.11 CDO77108.1 - 7 5.9 15.1 12 5.1 10.4 1.5 1 0 0 1 1 1 0 Vta1 like F-box PF00646.28 CDO77109.1 - 0.0019 17.8 0.2 0.0038 16.8 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO77109.1 - 0.0088 15.7 0.7 0.017 14.8 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 CDO77109.1 - 0.013 15.1 0.0 0.014 15.0 0.0 1.4 1 1 0 1 1 1 0 F-box-like domain F-box PF00646.28 CDO77110.1 - 2.4e-07 30.2 0.5 7.2e-07 28.6 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO77110.1 - 0.00069 19.2 2.6 0.0018 17.9 1.4 2.0 2 0 0 2 2 2 1 F-box-like MARVEL PF01284.18 CDO77111.1 - 6.2e-05 22.8 12.1 6.2e-05 22.8 8.4 1.4 1 1 0 1 1 1 1 Membrane-associating domain UPF0182 PF03699.8 CDO77111.1 - 0.033 12.1 4.2 0.051 11.5 2.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Yip1 PF04893.12 CDO77111.1 - 4.4 6.7 21.0 6.2 6.2 14.6 1.2 1 0 0 1 1 1 0 Yip1 domain MCLC PF05934.6 CDO77111.1 - 7.7 4.6 6.8 9.7 4.3 4.7 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) E1-E2_ATPase PF00122.15 CDO77112.1 - 2.8e-51 173.7 2.9 2.8e-51 173.7 2.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CDO77112.1 - 1.5e-32 112.5 3.5 1.5e-32 112.5 2.4 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CDO77112.1 - 5.9e-30 105.2 0.3 2.6e-28 99.9 0.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDO77112.1 - 1.2e-16 60.4 0.0 2.4e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CDO77112.1 - 3.3e-14 53.4 0.0 2.1e-13 50.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CDO77112.1 - 4.9e-10 38.7 0.0 1.1e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CDO77112.1 - 5.5e-08 32.6 0.4 1e-07 31.8 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.12 CDO77113.1 - 3e-46 157.5 0.0 4.8e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDO77113.1 - 1.5e-41 142.3 0.0 2.4e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 CDO77113.1 - 0.00039 19.8 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CDO77113.1 - 0.0045 16.0 0.0 0.0076 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family nec1 PF10379.4 CDO77114.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Virulence protein nec1 DUF883 PF05957.8 CDO77115.1 - 0.32 11.4 6.5 3.7 8.0 2.0 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Abhydrolase_3 PF07859.8 CDO77116.1 - 1.7e-25 89.8 0.0 2.2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CDO77116.1 - 0.02 14.1 0.0 0.037 13.3 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S51 PF03575.12 CDO77116.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 Abhydrolase_3 PF07859.8 CDO77117.1 - 4.7e-42 143.9 0.0 6.2e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CDO77117.1 - 7.3e-05 21.6 0.0 0.00022 20.0 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Myb_DNA-bind_5 PF13873.1 CDO77118.1 - 0.0014 18.4 0.1 0.0098 15.7 0.3 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF605 PF04652.11 CDO77119.1 - 2.1 7.6 10.7 3.2 7.0 7.4 1.3 1 0 0 1 1 1 0 Vta1 like Metallophos_2 PF12850.2 CDO77120.1 - 2.7e-18 66.3 0.1 3.5e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CDO77120.1 - 5.4e-07 29.1 0.9 0.021 14.2 0.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase UPF0203 PF05254.7 CDO77121.1 - 2.3e-19 69.0 4.2 4.2e-18 64.9 2.9 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 CDO77121.1 - 0.037 13.9 1.7 5.2 7.0 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein YbfN PF13982.1 CDO77121.1 - 0.058 13.5 2.1 0.84 9.8 0.4 2.5 1 1 1 2 2 2 0 YbfN-like lipoprotein Cmc1 PF08583.5 CDO77121.1 - 0.091 12.5 1.1 7 6.5 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 CDO77121.1 - 0.1 12.6 0.7 7.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) COX6B PF02297.12 CDO77121.1 - 0.24 11.4 6.2 3.1 7.8 0.2 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 CDO77121.1 - 0.33 11.0 1.9 9.6 6.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Zn_clus PF00172.13 CDO77122.1 - 5.2e-08 32.6 11.3 5.2e-08 32.6 7.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 CDO77122.1 - 2.2 7.8 6.7 5 6.7 4.7 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Yippee-Mis18 PF03226.9 CDO77123.1 - 1.4e-12 47.4 0.0 2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LIM PF00412.17 CDO77123.1 - 0.049 13.7 0.6 11 6.1 0.1 2.2 2 0 0 2 2 2 0 LIM domain Gin PF10764.4 CDO77123.1 - 0.13 11.9 1.2 0.98 9.1 0.1 2.1 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin HNH_5 PF14279.1 CDO77123.1 - 0.14 12.1 0.4 0.74 9.8 0.0 2.0 2 0 0 2 2 2 0 HNH endonuclease Amidohydro_4 PF13147.1 CDO77124.1 - 8.4e-19 68.6 2.1 1.3e-17 64.8 1.5 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CDO77124.1 - 1.2e-16 61.3 0.0 1.8e-16 60.6 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CDO77124.1 - 9.3e-11 41.4 0.4 2.1e-10 40.2 0.3 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 CDO77124.1 - 0.11 12.0 0.0 0.34 10.4 0.0 1.7 1 1 0 1 1 1 0 Amidohydrolase Pkinase PF00069.20 CDO77125.1 - 0.0003 20.0 0.0 0.005 16.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain RVT_3 PF13456.1 CDO77126.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_1 PF00078.22 CDO77126.1 - 0.17 11.2 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ATP-synt_C PF00137.16 CDO77127.1 - 4.8e-21 74.4 25.7 3.5e-12 46.0 4.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C KRTAP PF11759.3 CDO77127.1 - 5.3 7.3 12.4 1.6 9.0 3.5 2.3 2 0 0 2 2 2 0 Keratin-associated matrix zf-CCHC_3 PF13917.1 CDO77128.1 - 1.4e-19 69.4 0.5 2.2e-19 68.8 0.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CDO77128.1 - 0.021 14.7 1.2 0.031 14.2 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 CDO77128.1 - 0.069 12.6 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDO77128.1 - 0.077 13.0 0.5 0.15 12.1 0.3 1.5 1 0 0 1 1 1 0 DnaJ central domain Rtt106 PF08512.7 CDO77129.1 - 1.2e-09 38.0 0.0 2.5e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Histone chaperone Rttp106-like Nop14 PF04147.7 CDO77129.1 - 1.5 6.6 16.3 2.2 6.1 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CDO77129.1 - 3 6.2 12.9 4.7 5.5 8.9 1.3 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 CDO77129.1 - 5.3 4.9 9.5 8.2 4.3 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S28 PF05577.7 CDO77131.1 - 9.9e-49 166.0 0.0 1.8e-48 165.1 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 SIR2 PF02146.12 CDO77132.1 - 1.2e-43 148.9 0.0 1.7e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF164 PF02591.10 CDO77132.1 - 0.14 12.0 0.8 0.29 10.9 0.6 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain Paired_CXXCH_1 PF09699.5 CDO77132.1 - 0.2 11.2 1.7 0.46 10.0 1.2 1.6 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) DNA_RNApol_7kD PF03604.8 CDO77132.1 - 0.64 9.5 4.0 3.1 7.3 2.8 2.0 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit SIR2 PF02146.12 CDO77133.1 - 6.6e-09 35.7 0.0 9.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Abhydrolase_3 PF07859.8 CDO77134.1 - 8.2e-15 54.9 0.0 4.3e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO77134.1 - 1.9e-09 37.4 0.0 4.7e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CDO77134.1 - 4.8e-09 35.7 0.0 0.00032 20.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 CDO77134.1 - 0.001 18.3 0.0 1.7 7.8 0.0 2.9 3 0 0 3 3 3 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 CDO77134.1 - 0.033 13.6 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Cullin PF00888.17 CDO77135.1 - 1.4e-47 162.5 0.0 2e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 CDO77135.1 - 2.8e-10 40.3 0.0 6.2e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 DUF2235 PF09994.4 CDO77136.1 - 6.1e-52 176.6 0.0 1.3e-50 172.3 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Transket_pyr PF02779.19 CDO77137.1 - 3.7e-66 221.9 0.0 6e-66 221.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CDO77137.1 - 3.7e-58 196.6 0.0 5.8e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component MBD_C PF14048.1 CDO77137.1 - 0.19 12.3 0.0 0.46 11.0 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 CoA_transf_3 PF02515.12 CDO77138.1 - 4.8e-65 218.3 0.0 6.4e-65 217.9 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Glyco_hydro_cc PF11790.3 CDO77138.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Glyco_hydro_30 PF02055.11 CDO77140.1 - 7.1e-34 116.8 2.2 1e-33 116.3 1.5 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 CDO77140.1 - 0.018 13.9 0.2 0.14 11.0 0.1 2.0 1 1 0 1 1 1 0 O-Glycosyl hydrolase family 30 Amidase_2 PF01510.20 CDO77140.1 - 0.094 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase HD_5 PF13487.1 CDO77140.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 HD domain Aldo_ket_red PF00248.16 CDO77141.1 - 5.4e-63 212.4 0.1 6.1e-63 212.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 3Beta_HSD PF01073.14 CDO77141.1 - 0.033 12.9 0.1 0.052 12.2 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aldo_ket_red PF00248.16 CDO77142.1 - 7.1e-56 189.1 0.1 1.1e-55 188.4 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_1 PF00561.15 CDO77142.1 - 0.029 13.9 0.0 0.26 10.8 0.0 2.2 2 1 1 3 3 3 0 alpha/beta hydrolase fold WD40 PF00400.27 CDO77143.1 - 0.0015 18.3 1.1 0.019 14.8 0.0 2.8 3 1 0 3 3 3 1 WD domain, G-beta repeat adh_short PF00106.20 CDO77144.1 - 0.0024 17.8 0.1 0.0089 15.9 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Heme_oxygenase PF01126.15 CDO77145.1 - 1.6e-40 138.9 0.0 2.2e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase zf-CCCH PF00642.19 CDO77146.1 - 9.6e-16 57.0 20.1 5e-07 29.2 0.5 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CDO77146.1 - 9.8e-06 25.3 18.4 0.0068 16.3 0.3 4.0 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type zf-RING_2 PF13639.1 CDO77147.1 - 3.9e-13 48.9 1.2 3.9e-13 48.9 0.8 2.3 2 0 0 2 2 2 1 Ring finger domain PA PF02225.17 CDO77147.1 - 8.6e-13 47.8 0.0 1.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.1 CDO77147.1 - 4.2e-07 29.5 0.5 7.6e-07 28.7 0.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CDO77147.1 - 3.9e-06 26.7 2.4 8.6e-06 25.6 1.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDO77147.1 - 6.9e-06 26.0 1.4 6.9e-06 26.0 1.0 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDO77147.1 - 7.7e-06 25.4 1.1 1.5e-05 24.5 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO77147.1 - 5.7e-05 22.6 0.7 0.00011 21.7 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDO77147.1 - 0.055 13.1 3.6 3.3 7.5 0.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger BatD PF13584.1 CDO77147.1 - 0.28 9.7 0.6 0.4 9.2 0.3 1.3 1 1 0 1 1 1 0 Oxygen tolerance Gelsolin PF00626.17 CDO77148.1 - 1.5e-32 111.1 0.0 1.8e-16 59.6 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat Aldo_ket_red PF00248.16 CDO77149.1 - 9.2e-49 165.7 0.0 1.2e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BTB PF00651.26 CDO77150.1 - 0.0014 18.6 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Asp PF00026.18 CDO77151.1 - 9.1e-46 156.5 13.7 1.8e-45 155.5 9.5 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO77151.1 - 4e-07 30.1 4.8 2.3e-06 27.6 1.5 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO77151.1 - 0.0017 18.8 5.9 0.032 14.7 0.4 3.3 3 0 0 3 3 3 2 Aspartyl protease DUF3924 PF13062.1 CDO77151.1 - 0.038 13.8 0.0 0.15 11.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) TAXi_C PF14541.1 CDO77151.1 - 0.055 13.0 0.2 0.23 10.9 0.1 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Glyco_transf_34 PF05637.7 CDO77153.1 - 0.097 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Methyltransf_33 PF10017.4 CDO77155.1 - 9.4e-33 112.8 0.0 1.5e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 CDO77155.1 - 2.3e-20 73.0 4.7 3.1e-10 39.8 0.0 3.0 3 0 0 3 3 3 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 CDO77155.1 - 0.00054 20.2 0.2 0.0011 19.3 0.1 1.5 1 0 0 1 1 1 1 DinB superfamily LINES_C PF14695.1 CDO77156.1 - 0.037 13.2 0.1 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Lines C-terminus CSTF2_hinge PF14327.1 CDO77156.1 - 0.059 13.4 1.5 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Ribonuc_red_lgC PF02867.10 CDO77157.1 - 3e-197 656.4 0.0 2.7e-194 646.7 0.0 2.2 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CDO77157.1 - 6.8e-23 80.2 0.0 1.5e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CDO77157.1 - 3.2e-06 27.4 0.0 8.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain F-box-like PF12937.2 CDO77158.1 - 7.5e-09 35.1 1.4 1.9e-08 33.9 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO77158.1 - 0.079 12.6 2.5 1.5 8.5 1.6 3.0 1 1 0 1 1 1 0 F-box domain FA_desaturase PF00487.19 CDO77159.1 - 2.7e-26 92.5 21.7 5.6e-26 91.5 15.0 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Pkinase PF00069.20 CDO77160.1 - 3.8e-21 75.4 0.0 6e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77160.1 - 6.1e-06 25.5 0.0 2e-05 23.8 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CDO77160.1 - 0.0082 15.9 0.6 0.044 13.5 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_30 PF02055.11 CDO77161.1 - 4e-26 91.3 0.1 7.7e-26 90.3 0.1 1.4 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Methyltransf_33 PF10017.4 CDO77162.1 - 6.4e-25 87.4 0.0 9.2e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent YTH PF04146.10 CDO77163.1 - 4.5e-40 136.4 0.0 1.2e-27 96.2 0.0 2.2 2 0 0 2 2 2 2 YT521-B-like domain RRM_1 PF00076.17 CDO77163.1 - 1.4e-05 24.6 0.0 0.0044 16.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO77163.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO77163.1 - 0.021 14.7 0.0 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CDO77164.1 - 2.3e-22 77.9 0.1 1.5e-05 24.6 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.1 CDO77164.1 - 0.004 16.6 0.0 0.0096 15.3 0.0 1.5 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 CDO77164.1 - 0.0083 14.3 0.1 0.098 10.7 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF3312 PF11768.3 CDO77164.1 - 0.017 13.3 0.0 0.024 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 CDO77164.1 - 0.086 11.1 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain A_deaminase PF00962.17 CDO77165.1 - 4.8e-111 370.8 0.3 6.4e-111 370.4 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase rve PF00665.21 CDO77169.1 - 7.7e-23 80.8 0.0 1.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO77169.1 - 2.4e-07 30.2 0.1 4.8e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CDO77169.1 - 0.00046 19.5 0.0 0.00085 18.6 0.0 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Imm47 PF15586.1 CDO77169.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 47 MAP7 PF05672.6 CDO77170.1 - 0.0086 15.4 6.0 0.0086 15.4 4.2 2.4 2 0 0 2 2 2 2 MAP7 (E-MAP-115) family rve PF00665.21 CDO77172.1 - 1e-19 70.8 0.1 2.1e-19 69.7 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CDO77172.1 - 1.7e-16 60.2 0.0 3.2e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CDO77172.1 - 7.2e-08 31.9 0.9 1.5e-07 31.0 0.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 CDO77172.1 - 5.2e-05 23.6 0.1 0.00013 22.3 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDO77172.1 - 0.029 14.2 0.2 0.061 13.2 0.1 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF905 PF06006.7 CDO77172.1 - 0.042 13.2 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) zf-CCHC_3 PF13917.1 CDO77173.1 - 0.11 12.1 0.8 0.27 10.9 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Hydrolase PF00702.21 CDO77175.1 - 2.7e-06 27.9 0.0 3.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDO77175.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit tRNA-synt_2 PF00152.15 CDO77176.1 - 3.8e-79 265.8 0.0 5.6e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 CDO77176.1 - 8.2e-21 74.0 0.0 1.2e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 CDO77176.1 - 5.4e-05 22.9 0.1 9.4e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CDO77176.1 - 0.0035 16.5 0.1 0.25 10.5 0.1 2.4 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Pro_isomerase PF00160.16 CDO77177.1 - 9.1e-36 123.4 0.2 2e-35 122.2 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAM60A PF15396.1 CDO77177.1 - 0.82 9.3 24.1 0.35 10.5 9.3 2.1 1 1 1 2 2 2 0 Protein Family FAM60A Borrelia_P83 PF05262.6 CDO77177.1 - 4.3 5.4 14.5 6.5 4.9 10.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Ras PF00071.17 CDO77178.1 - 1.4e-21 76.5 0.1 4.2e-13 48.9 0.0 2.9 1 1 1 2 2 2 2 Ras family GTP_EFTU PF00009.22 CDO77178.1 - 5.4e-05 22.7 0.1 0.036 13.4 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain ImcF-related_N PF14331.1 CDO77178.1 - 0.0068 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 ImcF-related N-terminal domain Ribosom_S12_S23 PF00164.20 CDO77178.1 - 0.08 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S12/S23 FeoB_N PF02421.13 CDO77178.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B DEAD PF00270.24 CDO77179.1 - 2.3e-48 163.8 0.0 1.4e-46 158.0 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CDO77179.1 - 3.3e-10 39.6 0.0 8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO77179.1 - 4.1e-06 26.7 0.0 1.4e-05 25.0 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2443 PF10398.4 CDO77179.1 - 0.029 14.1 0.3 0.057 13.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Helicase_C PF00271.26 CDO77180.1 - 2.9e-11 43.0 0.2 4.8e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RAM PF15320.1 CDO77180.1 - 0.082 13.1 4.3 0.14 12.4 3.0 1.4 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein API5 PF05918.6 CDO77180.1 - 6.4 5.1 11.9 8.2 4.7 8.2 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) eIF-4B PF06273.6 CDO77180.1 - 7.6 5.1 8.5 7.9 5.0 5.9 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B APC10 PF03256.11 CDO77183.1 - 4.4e-43 147.1 0.0 1e-42 145.9 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PHD PF00628.24 CDO77183.1 - 3.7e-08 32.9 8.2 7.5e-08 31.9 5.7 1.5 1 0 0 1 1 1 1 PHD-finger F5_F8_type_C PF00754.20 CDO77183.1 - 0.00083 19.1 0.0 0.0032 17.3 0.0 2.0 1 0 0 1 1 1 1 F5/8 type C domain ThiF PF00899.16 CDO77184.1 - 2.2e-31 108.4 0.0 3.4e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CDO77184.1 - 4e-26 90.4 0.3 1.3e-25 88.7 0.0 2.0 2 0 0 2 2 2 1 MoeZ/MoeB domain Rhodanese PF00581.15 CDO77184.1 - 1.8e-13 50.8 0.0 2.7e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain zf-Tim10_DDP PF02953.10 CDO77185.1 - 3e-21 74.4 2.5 4.3e-21 73.9 1.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Condensin2nSMC PF12422.3 CDO77185.1 - 0.069 12.8 0.1 0.085 12.6 0.1 1.1 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit DUF4010 PF13194.1 CDO77185.1 - 0.15 11.2 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) DnaJ PF00226.26 CDO77186.1 - 1e-23 82.7 0.8 1e-23 82.7 0.6 1.9 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 CDO77186.1 - 5.8e-10 39.0 0.2 1.2e-09 37.9 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CDO77186.1 - 2.1e-08 34.0 0.5 4.6e-08 32.9 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CDO77186.1 - 0.0027 17.8 0.5 0.0062 16.6 0.4 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CDO77186.1 - 0.053 13.8 0.2 0.24 11.8 0.2 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger LTXXQ PF07813.7 CDO77186.1 - 0.4 11.1 0.0 0.4 11.1 0.0 4.0 5 1 0 5 5 5 0 LTXXQ motif family protein RVT_2 PF07727.9 CDO77187.1 - 3.2e-75 252.2 0.0 4.6e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_18 PF00704.23 CDO77188.1 - 1e-60 206.0 1.9 1e-59 202.7 1.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.19 CDO77188.1 - 6.3e-13 48.5 0.0 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 PX domain adh_short PF00106.20 CDO77189.1 - 4.2e-17 62.5 2.1 5.7e-17 62.1 0.9 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDO77189.1 - 2.1e-07 30.9 0.0 1.3e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CDO77189.1 - 8e-06 25.9 0.6 2.2e-05 24.5 0.3 1.7 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 CDO77189.1 - 4e-05 23.3 0.6 7.9e-05 22.3 0.5 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CDO77189.1 - 0.00027 20.4 0.1 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 CDO77189.1 - 0.075 11.9 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 CDO77189.1 - 0.087 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PALP PF00291.20 CDO77190.1 - 2e-53 181.6 4.5 5.9e-45 153.8 1.3 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme TAF4 PF05236.9 CDO77192.1 - 1.2e-31 110.0 3.5 2.1e-31 109.2 2.4 1.3 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family PAT1 PF09770.4 CDO77192.1 - 2.5 6.2 10.0 3.1 5.9 6.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 CDO77192.1 - 2.9 7.5 0.0 2.9 7.5 0.0 2.7 2 1 1 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.8 CDO77192.1 - 4.6 7.0 11.4 6.3 6.5 7.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rotamase_2 PF13145.1 CDO77192.1 - 5.7 7.6 11.1 2.7 8.6 5.5 2.1 1 1 1 2 2 2 0 PPIC-type PPIASE domain ABC_membrane PF00664.18 CDO77193.1 - 1.6e-47 162.2 28.1 3.3e-23 82.4 1.4 3.9 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.22 CDO77193.1 - 7e-47 159.1 0.1 3.9e-28 98.4 0.1 3.2 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CDO77193.1 - 6.8e-13 49.2 0.1 0.0082 16.1 0.0 4.4 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 CDO77193.1 - 1.4e-11 44.1 4.2 0.0038 16.4 0.3 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CDO77193.1 - 4.4e-08 32.5 0.1 0.0078 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CDO77193.1 - 3.2e-07 30.8 2.0 0.0001 22.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 CDO77193.1 - 1.1e-06 28.2 0.0 0.0093 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 CDO77193.1 - 1.8e-06 27.1 0.0 0.0018 17.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CDO77193.1 - 1.5e-05 24.5 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 CDO77193.1 - 1.7e-05 24.9 1.5 0.2 11.5 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 CDO77193.1 - 9.9e-05 22.8 0.0 0.97 9.9 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 CDO77193.1 - 0.00011 23.0 0.5 0.98 10.2 0.1 3.3 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 CDO77193.1 - 0.00011 21.9 1.0 0.36 10.5 0.0 2.8 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 CDO77193.1 - 0.00015 21.6 0.6 0.023 14.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 CDO77193.1 - 0.00019 21.5 1.6 0.1 12.7 0.0 3.3 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CDO77193.1 - 0.00021 21.0 0.0 0.096 12.3 0.0 3.1 3 1 0 3 3 3 1 Archaeal ATPase MMR_HSR1 PF01926.18 CDO77193.1 - 0.00021 21.1 0.1 0.17 11.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 CDO77193.1 - 0.00052 20.3 0.1 2.5 8.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 CDO77193.1 - 0.00096 18.3 0.1 0.4 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CDO77193.1 - 0.0013 18.2 1.4 1.5 8.2 0.0 2.8 2 1 0 3 3 3 2 AAA-like domain Zeta_toxin PF06414.7 CDO77193.1 - 0.003 16.7 0.0 0.47 9.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 CDO77193.1 - 0.0044 16.4 0.8 4.7 6.5 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein ResIII PF04851.10 CDO77193.1 - 0.0084 15.9 0.0 0.47 10.2 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 CDO77193.1 - 0.0087 15.7 0.3 7.3 6.3 0.1 3.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CDO77193.1 - 0.01 15.7 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 CDO77193.1 - 0.014 14.0 0.1 0.05 12.2 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein Dynamin_N PF00350.18 CDO77193.1 - 0.019 14.7 0.2 2.4 7.9 0.0 2.8 2 0 0 2 2 2 0 Dynamin family AAA_19 PF13245.1 CDO77193.1 - 0.021 14.5 0.2 0.54 10.0 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain DEAD PF00270.24 CDO77193.1 - 0.031 13.7 0.1 11 5.4 0.1 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.1 CDO77193.1 - 0.048 13.2 0.5 0.18 11.3 0.0 2.1 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.7 CDO77193.1 - 0.063 12.5 1.1 3.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein PduV-EutP PF10662.4 CDO77193.1 - 0.08 12.4 0.5 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 CDO77193.1 - 0.1 12.5 0.2 2.7 7.8 0.0 3.2 4 0 0 4 4 4 0 AAA domain Tubulin PF00091.20 CDO77193.1 - 0.25 11.1 0.3 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain cobW PF02492.14 CDO77193.1 - 0.57 9.6 2.8 1.4 8.2 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 CDO77193.1 - 0.67 9.6 6.1 2.2 7.8 0.1 3.6 4 0 0 4 4 4 0 NACHT domain Peptidase_M24 PF00557.19 CDO77194.1 - 9.9e-36 123.2 0.0 1.4e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Nup188 PF10487.4 CDO77195.1 - 7.8e-19 67.1 0.5 1.1e-14 53.3 0.1 3.2 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DUF3414 PF11894.3 CDO77195.1 - 1.8e-06 25.2 1.9 1.4e-05 22.2 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3414) Ribosomal_L13 PF00572.13 CDO77196.1 - 2.9e-48 163.1 0.3 3.5e-48 162.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 X PF00739.14 CDO77196.1 - 0.023 14.6 0.1 0.46 10.3 0.0 2.1 1 1 0 2 2 2 0 Trans-activation protein X SH3_9 PF14604.1 CDO77198.1 - 5.4e-16 57.9 0.1 1.2e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 CDO77198.1 - 9.8e-15 54.6 0.1 2.4e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 CDO77198.1 - 1e-14 53.6 0.2 2e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 CDO77198.1 - 7.7e-13 48.0 0.0 1.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 CDO77198.1 - 1.3e-10 40.6 0.0 2.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 CDO77198.1 - 1.4e-10 41.1 0.0 3.6e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 CDO77198.1 - 0.0065 16.7 0.6 0.0065 16.7 0.4 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain CH PF00307.26 CDO77198.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain Ste50p-SAM PF09235.5 CDO77198.1 - 0.14 12.1 0.2 0.32 11.0 0.2 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_PNT PF02198.11 CDO77198.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain TPR_11 PF13414.1 CDO77199.1 - 5e-21 74.1 0.3 1.1e-06 28.2 0.0 6.0 3 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 CDO77199.1 - 1.2e-17 62.3 6.0 0.00023 20.8 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDO77199.1 - 1.3e-15 56.2 0.2 0.00079 18.9 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CDO77199.1 - 5.7e-14 52.3 7.5 1.5e-07 31.8 0.0 6.4 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDO77199.1 - 9.8e-14 51.0 3.0 0.0014 18.5 0.0 5.9 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CDO77199.1 - 9.6e-12 44.4 10.0 0.0024 18.3 0.0 7.7 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDO77199.1 - 1.8e-09 37.0 0.0 0.11 12.7 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CDO77199.1 - 2.2e-08 33.2 7.1 0.11 12.3 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO77199.1 - 3e-08 33.8 0.0 0.023 15.0 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO77199.1 - 3.9e-07 29.3 0.0 3.3 7.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 CDO77199.1 - 2.2e-05 24.1 10.7 0.046 13.6 0.1 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CDO77199.1 - 0.00036 20.6 0.0 0.18 11.9 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CDO77199.1 - 0.0014 18.9 1.1 16 6.1 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat RPN7 PF10602.4 CDO77199.1 - 0.004 16.5 0.2 0.32 10.3 0.0 3.5 4 0 0 4 4 4 1 26S proteasome subunit RPN7 TPR_9 PF13371.1 CDO77199.1 - 0.0083 15.9 11.0 0.18 11.6 0.0 5.3 5 1 2 7 7 6 2 Tetratricopeptide repeat Semialdhyde_dhC PF02774.13 CDO77201.1 - 6.7e-38 130.3 0.0 9.4e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 CDO77201.1 - 1.1e-27 96.7 0.0 1.7e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CDO77201.1 - 0.027 14.3 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 CDO77201.1 - 0.029 14.9 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RNase_PH PF01138.16 CDO77202.1 - 2e-16 60.4 0.0 3.3e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CDO77202.1 - 0.00095 19.0 0.1 0.0039 17.0 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Dioxygenase_C PF00775.16 CDO77203.1 - 6.1e-21 74.5 0.1 1.2e-20 73.4 0.0 1.5 1 1 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.1 CDO77203.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Glyco_hydro_61 PF03443.9 CDO77204.1 - 2.5e-63 213.7 0.6 3.1e-63 213.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 CDO77204.1 - 2.5e-14 52.6 8.4 2.5e-14 52.6 5.8 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain F-box-like PF12937.2 CDO77205.1 - 0.013 15.2 0.7 0.045 13.4 0.5 2.1 1 1 0 1 1 1 0 F-box-like Elongin_A PF06881.6 CDO77205.1 - 0.087 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A SMC_N PF02463.14 CDO77206.1 - 4.5e-21 75.1 0.0 7.5e-21 74.3 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CDO77206.1 - 1.8e-05 25.1 39.8 1.8e-05 25.1 27.6 5.6 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CDO77206.1 - 0.002 18.1 9.1 0.0022 18.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CDO77206.1 - 0.002 17.6 0.0 0.0091 15.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_13 PF13166.1 CDO77206.1 - 0.0042 15.6 0.0 0.0042 15.6 0.0 5.2 3 2 2 5 5 5 2 AAA domain AAA PF00004.24 CDO77206.1 - 0.021 15.0 0.6 0.14 12.4 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CDO77206.1 - 0.041 13.2 2.4 0.53 9.6 0.0 3.6 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 CDO77206.1 - 0.88 9.8 0.0 0.88 9.8 0.0 5.3 4 2 0 5 5 5 0 ABC transporter AAA_17 PF13207.1 CDO77206.1 - 1.6 9.5 0.0 1.6 9.5 0.0 4.9 4 2 0 4 4 4 0 AAA domain DUF2730 PF10805.3 CDO77206.1 - 5.5 6.7 18.5 0.62 9.8 3.9 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF2730) Ham1p_like PF01725.11 CDO77207.1 - 1.7e-44 151.4 0.0 1.6e-24 86.3 0.0 2.0 1 1 1 2 2 2 2 Ham1 family Pkinase PF00069.20 CDO77208.1 - 9.6e-54 182.2 0.0 1.6e-53 181.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77208.1 - 8.4e-29 100.4 0.0 1.1e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO77208.1 - 0.0014 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDO77208.1 - 0.002 17.2 0.1 0.0048 15.9 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDO77208.1 - 0.0044 16.7 1.2 0.016 14.9 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CDO77208.1 - 0.0055 15.5 0.0 0.008 15.0 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase SAP18 PF06487.7 CDO77209.1 - 3.7e-10 39.6 0.0 5e-08 32.7 0.0 2.2 1 1 1 2 2 2 2 Sin3 associated polypeptide p18 (SAP18) 2OG-FeII_Oxy_2 PF13532.1 CDO77210.1 - 1.9e-17 63.7 0.0 2.5e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CDO77210.1 - 3.5e-06 27.2 0.0 6.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Terpene_synth_C PF03936.11 CDO77211.1 - 5.2e-18 65.2 0.0 7.6e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Sugar_tr PF00083.19 CDO77212.1 - 2.9e-80 270.0 21.6 3.3e-80 269.8 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO77212.1 - 4.1e-28 98.1 31.8 7.5e-26 90.6 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CDO77212.1 - 3.6e-10 38.6 3.2 5.5e-10 38.0 2.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 CDO77212.1 - 1e-05 24.1 7.3 1e-05 24.1 5.0 2.9 2 2 0 2 2 2 2 MFS/sugar transport protein Asp PF00026.18 CDO77213.1 - 6.7e-70 235.8 1.8 8e-70 235.5 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CDO77213.1 - 1.5e-07 31.7 0.4 8.3e-05 23.0 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 CDO77213.1 - 3.5e-07 30.3 0.0 2.1e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.18 CDO77214.1 - 2.7e-70 237.1 2.9 3.5e-70 236.7 2.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CDO77214.1 - 1.8e-06 28.3 3.6 0.00023 21.5 0.1 3.1 2 2 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 CDO77214.1 - 0.016 15.1 0.0 0.14 12.0 0.0 2.3 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Fimbrial_PilY2 PF14481.1 CDO77214.1 - 0.05 13.0 0.2 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 DUF1768 PF08719.6 CDO77215.1 - 5.3e-06 26.2 0.0 8.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_1 PF00076.17 CDO77216.1 - 2.6e-06 26.9 0.1 0.042 13.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CDO77216.1 - 6.2e-06 26.0 0.0 0.00057 19.6 0.0 2.5 1 1 0 1 1 1 1 RNA binding motif RRM_6 PF14259.1 CDO77216.1 - 4.6e-05 23.3 0.0 0.0066 16.3 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO77216.1 - 0.021 14.6 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.12 CDO77216.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 La domain p450 PF00067.17 CDO77217.1 - 3.6e-52 177.4 0.0 5.2e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 CDO77218.1 - 0.00048 18.7 0.0 0.00087 17.9 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 zf-MYND PF01753.13 CDO77219.1 - 1.1e-08 34.7 11.7 2.6e-08 33.5 8.1 1.7 1 0 0 1 1 1 1 MYND finger WSC PF01822.14 CDO77220.1 - 1.5e-29 101.7 17.7 2.3e-15 56.2 5.4 2.1 2 0 0 2 2 2 2 WSC domain AP_endonuc_2 PF01261.19 CDO77221.1 - 5.7e-24 84.6 0.0 1.2e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel F-box PF00646.28 CDO77221.1 - 0.0021 17.6 5.2 0.37 10.5 0.4 2.8 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 CDO77221.1 - 0.38 10.5 4.1 0.56 9.9 0.1 2.6 2 0 0 2 2 2 0 F-box-like zf-MYND PF01753.13 CDO77222.1 - 1.4e-06 28.0 10.7 2.7e-06 27.1 7.4 1.5 1 0 0 1 1 1 1 MYND finger CheF-arch PF04283.7 CDO77224.1 - 0.12 11.5 0.2 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Chemotaxis signal transduction system protein F from archaea Polysacc_deac_1 PF01522.16 CDO77225.1 - 1.5e-16 60.1 0.0 3.1e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 CDO77225.1 - 0.032 13.6 0.0 0.047 13.0 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.4 CDO77225.1 - 0.082 10.9 0.0 0.12 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) AA_permease_2 PF13520.1 CDO77226.1 - 1.7e-56 191.6 54.5 2e-56 191.3 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CDO77226.1 - 2.7e-17 62.2 46.9 3.8e-17 61.7 32.5 1.2 1 0 0 1 1 1 1 Amino acid permease TipAS PF07739.8 CDO77227.1 - 0.0014 18.9 3.0 0.0014 18.9 2.1 2.3 1 1 1 2 2 2 1 TipAS antibiotic-recognition domain DUF3584 PF12128.3 CDO77227.1 - 0.0024 15.3 14.4 0.0029 15.0 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) VSG_B PF13206.1 CDO77227.1 - 0.33 10.0 15.0 0.52 9.3 10.4 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain LLC1 PF14945.1 CDO77227.1 - 0.35 11.1 4.3 0.68 10.2 3.0 1.5 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein CDC37_N PF03234.9 CDO77227.1 - 0.47 10.7 6.4 0.91 9.8 4.5 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF3359 PF11839.3 CDO77227.1 - 0.72 10.2 13.2 1.7 9.0 9.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) DUF2229 PF09989.4 CDO77227.1 - 0.82 9.0 4.1 1.2 8.5 2.8 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Glyoxal_oxid_N PF07250.6 CDO77228.1 - 2.4e-65 220.0 0.0 1e-64 217.9 0.0 2.1 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CDO77228.1 - 1.8e-18 66.4 0.1 3.5e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.10 CDO77228.1 - 0.006 16.2 0.0 1 9.2 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 CDO77228.1 - 0.0068 16.1 1.2 16 5.3 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 CDO77229.1 - 5.5e-64 215.5 0.0 2.3e-63 213.5 0.0 2.1 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CDO77229.1 - 1.4e-20 73.2 0.1 2.8e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 CDO77229.1 - 0.00083 19.0 1.7 2 8.2 0.0 4.7 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CDO77229.1 - 0.0074 16.0 0.0 0.92 9.3 0.0 3.5 3 0 0 3 3 3 1 Kelch motif DUF3197 PF11432.3 CDO77230.1 - 0.14 12.1 0.2 0.3 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) AA_permease PF00324.16 CDO77231.1 - 2.8e-111 372.2 47.8 3.5e-111 371.9 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CDO77231.1 - 1.3e-42 145.9 51.1 1.8e-42 145.4 35.4 1.2 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 CDO77232.1 - 1.5e-13 50.1 0.0 1.5e-13 50.1 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain DUF702 PF05142.7 CDO77232.1 - 0.0008 19.6 4.7 0.0018 18.4 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF702) FimP PF09766.4 CDO77232.1 - 0.0015 17.6 10.5 0.012 14.6 6.9 2.0 2 0 0 2 2 2 1 Fms-interacting protein Baculo_PP31 PF05311.6 CDO77232.1 - 0.033 13.4 3.6 0.054 12.7 2.5 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF808 PF05661.7 CDO77232.1 - 0.099 11.4 0.2 0.16 10.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) RED_N PF07808.8 CDO77232.1 - 0.12 11.5 8.5 0.18 10.9 5.9 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF4557 PF15101.1 CDO77232.1 - 0.2 11.4 11.9 0.33 10.7 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) HA2 PF04408.18 CDO77232.1 - 0.21 11.6 3.5 0.38 10.8 1.7 1.9 2 0 0 2 2 2 0 Helicase associated domain (HA2) Serinc PF03348.10 CDO77232.1 - 0.88 8.2 3.2 1.4 7.5 2.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) IncA PF04156.9 CDO77232.1 - 1 8.9 18.8 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 IncA protein DUF2360 PF10152.4 CDO77232.1 - 1.4 9.1 11.3 3.9 7.7 2.0 3.0 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) EMP24_GP25L PF01105.19 CDO77232.1 - 1.7 8.3 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 1 0 emp24/gp25L/p24 family/GOLD Suf PF05843.9 CDO77232.1 - 1.8 8.2 11.1 3.1 7.4 7.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ATAD4 PF15321.1 CDO77232.1 - 2.2 9.3 8.0 0.74 10.8 3.0 2.1 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 BaxI_1 PF12811.2 CDO77232.1 - 6.6 5.7 6.0 12 4.9 4.1 1.4 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF3138 PF11336.3 CDO77232.1 - 6.8 4.7 8.7 0.37 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) CDC14 PF08045.6 CDO77233.1 - 2.9e-22 79.0 0.0 4.2e-18 65.4 0.0 2.2 2 0 0 2 2 2 2 Cell division control protein 14, SIN component FAA_hydrolase PF01557.13 CDO77234.1 - 2.3e-56 190.6 0.0 3e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxal_oxid_N PF07250.6 CDO77235.1 - 2.3e-64 216.7 0.0 6.8e-64 215.2 0.0 1.7 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CDO77235.1 - 1.6e-19 69.7 0.1 3.3e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 CDO77235.1 - 0.0017 18.1 0.9 8.6 6.2 0.0 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain F-box-like PF12937.2 CDO77236.1 - 0.1 12.3 1.1 0.39 10.4 0.1 2.5 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.1 CDO77236.1 - 0.13 11.9 4.2 0.53 10.0 1.8 3.0 2 1 0 2 2 2 0 Leucine rich repeat Upf2 PF04050.9 CDO77236.1 - 1.3 8.7 7.6 1.4 8.6 3.1 2.2 2 0 0 2 2 2 0 Up-frameshift suppressor 2 TFIID-18kDa PF02269.11 CDO77237.1 - 1.8e-32 111.0 0.1 3.5e-32 110.0 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF3499 PF12005.3 CDO77237.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) Asp_protease PF09668.5 CDO77238.1 - 1.8e-61 205.2 0.0 2.7e-61 204.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 CDO77238.1 - 2e-10 41.0 0.0 6.2e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 CDO77238.1 - 7.8e-09 34.8 0.0 1.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 CDO77238.1 - 1.5e-08 34.1 0.5 4.4e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain gag-asp_proteas PF13975.1 CDO77238.1 - 2.3e-07 30.5 0.0 1.3e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CDO77238.1 - 2.1e-06 27.7 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease XPC-binding PF09280.6 CDO77238.1 - 0.00049 19.5 0.4 0.0017 17.7 0.1 1.9 2 0 0 2 2 2 1 XPC-binding domain UBA_4 PF14555.1 CDO77238.1 - 0.0006 19.2 0.0 0.0014 18.1 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain RVP PF00077.15 CDO77238.1 - 0.005 16.7 0.0 0.015 15.2 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 CDO77238.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like YfhD PF14151.1 CDO77238.1 - 0.3 11.2 1.4 0.61 10.2 0.9 1.4 1 0 0 1 1 1 0 YfhD-like protein RWD PF05773.17 CDO77240.1 - 2.5e-08 33.8 0.0 8.3e-08 32.1 0.0 1.9 2 1 0 2 2 2 1 RWD domain UPF0029 PF01205.14 CDO77240.1 - 0.00065 19.3 0.0 0.0019 17.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 Nop14 PF04147.7 CDO77241.1 - 0.13 10.2 12.3 0.24 9.3 8.5 1.5 1 0 0 1 1 1 0 Nop14-like family Aldedh PF00171.17 CDO77242.1 - 1.6e-153 511.4 0.7 1.8e-153 511.2 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Phage_RpbA PF10789.4 CDO77242.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA PDGLE PF13190.1 CDO77244.1 - 0.046 13.4 0.0 0.083 12.5 0.0 1.6 1 0 0 1 1 1 0 PDGLE domain DUF1517 PF07466.6 CDO77244.1 - 0.19 10.7 2.6 0.3 10.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) MGC-24 PF05283.6 CDO77244.1 - 0.41 10.4 3.8 0.78 9.5 2.7 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Beta-APP PF03494.8 CDO77244.1 - 0.64 9.5 4.8 1.2 8.6 3.4 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF1191 PF06697.7 CDO77246.1 - 0.032 13.0 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Rifin_STEVOR PF02009.11 CDO77246.1 - 0.058 13.0 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 CDO77246.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Hex_IIIa PF02455.11 CDO77246.1 - 0.12 11.0 1.5 0.16 10.6 1.1 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Hist_deacetyl PF00850.14 CDO77248.1 - 5.6e-57 193.3 0.0 6.9e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Ribosomal_L1 PF00687.16 CDO77249.1 - 9.5e-52 175.5 2.4 1.2e-51 175.2 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF647 PF04884.9 CDO77249.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis MULE PF10551.4 CDO77250.1 - 2e-08 34.2 0.0 5.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain RVT_2 PF07727.9 CDO77251.1 - 8.7e-65 218.1 0.0 1.2e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO77251.1 - 8e-15 55.0 0.0 1.9e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CDO77251.1 - 6.7e-09 35.2 0.0 1.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CDO77251.1 - 0.0053 16.2 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain UBN2_3 PF14244.1 CDO77251.1 - 0.069 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO77251.1 - 0.087 12.7 0.8 0.19 11.7 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 CDO77252.1 - 1.6e-15 57.2 0.0 2.8e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDO77252.1 - 0.00093 18.6 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain OpcA PF07239.6 CDO77252.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.4 2 0 0 2 2 2 0 Outer membrane protein OpcA Transposase_21 PF02992.9 CDO77253.1 - 4.7e-13 48.7 0.1 1.6e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Transposase family tnp2 DUF1315 PF07023.7 CDO77256.1 - 0.088 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1315) PfkB PF00294.19 CDO77257.1 - 1.6e-71 240.9 0.5 1.8e-71 240.7 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CDO77257.1 - 0.0076 15.4 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Cse1 PF08506.5 CDO77258.1 - 8.9e-05 21.2 0.0 0.00029 19.5 0.0 1.9 2 0 0 2 2 2 1 Cse1 RIX1 PF08167.7 CDO77258.1 - 0.00084 19.0 4.6 0.19 11.3 0.1 4.4 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis CAS_CSE1 PF03378.10 CDO77258.1 - 0.0018 16.6 0.4 0.048 11.9 0.0 3.0 3 1 1 4 4 4 1 CAS/CSE protein, C-terminus ParcG PF10274.4 CDO77258.1 - 0.098 12.5 1.9 3.8 7.3 0.1 3.6 4 1 0 4 4 4 0 Parkin co-regulated protein MMS19_C PF12460.3 CDO77258.1 - 0.16 10.6 1.7 1.5 7.5 0.1 2.9 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Malic_M PF03949.10 CDO77260.1 - 1e-70 238.2 0.0 6.1e-70 235.6 0.0 1.9 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CDO77260.1 - 9.9e-60 201.2 0.0 1.5e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PcrB PF01884.12 CDO77260.1 - 0.14 11.4 0.0 0.55 9.4 0.0 1.9 2 0 0 2 2 2 0 PcrB family F-box-like PF12937.2 CDO77261.1 - 7.6e-07 28.7 0.1 1.7e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like ABC2_membrane_3 PF12698.2 CDO77263.1 - 1.1e-13 50.9 15.1 1.4e-13 50.6 10.5 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein RCC1 PF00415.13 CDO77264.1 - 3.9e-13 49.3 0.1 0.00078 19.6 0.0 4.6 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDO77264.1 - 1.3e-08 34.1 4.7 2.6e-06 26.8 0.2 4.3 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat CorA PF01544.13 CDO77265.1 - 4.8e-14 52.0 6.9 3.8e-10 39.2 0.5 3.4 3 1 0 3 3 3 3 CorA-like Mg2+ transporter protein p450 PF00067.17 CDO77266.1 - 1.7e-23 82.8 0.0 3.4e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 DUF1631 PF07793.6 CDO77266.1 - 0.014 13.5 0.0 0.026 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) RdRP PF05183.7 CDO77267.1 - 4.1e-116 388.9 0.0 5.8e-116 388.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 CDO77269.1 - 6.1e-25 86.6 0.1 1.3e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO77269.1 - 1.8e-18 66.1 0.1 1.3e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO77269.1 - 5.6e-18 64.6 0.1 8.1e-10 38.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CDO77269.1 - 0.00035 20.2 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 Limkain b1 DUF3871 PF12987.2 CDO77269.1 - 0.072 11.7 0.2 7.9 5.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3871) FumaraseC_C PF10415.4 CDO77269.1 - 0.91 9.6 3.3 11 6.2 0.1 2.4 2 0 0 2 2 2 0 Fumarase C C-terminus Malic_M PF03949.10 CDO77270.1 - 6.3e-56 189.7 0.0 8.5e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CDO77270.1 - 2.7e-44 150.9 0.0 6.2e-44 149.7 0.0 1.6 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain NADH_oxidored PF08040.6 CDO77270.1 - 0.091 12.3 0.0 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 MNLL subunit LysM PF01476.15 CDO77271.1 - 9.4e-14 51.0 0.0 1.4e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 LysM domain Endomucin PF07010.7 CDO77271.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Endomucin UDPGT PF00201.13 CDO77272.1 - 5.3e-15 54.9 0.1 7.8e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CDO77272.1 - 0.00018 21.2 0.0 0.00038 20.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Amidohydro_2 PF04909.9 CDO77272.1 - 0.00053 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Glyco_trans_1_3 PF13528.1 CDO77272.1 - 0.015 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 Retrotrans_gag PF03732.12 CDO77272.1 - 0.021 14.8 0.0 0.07 13.2 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein NB PF04159.8 CDO77273.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 NB glycoprotein p450 PF00067.17 CDO77274.1 - 1.3e-71 241.5 0.1 1.3e-70 238.2 0.1 2.4 1 1 0 1 1 1 1 Cytochrome P450 Dor1 PF04124.7 CDO77276.1 - 8.2e-56 188.8 5.6 4.3e-55 186.5 3.9 2.0 1 1 0 1 1 1 1 Dor1-like family Vps51 PF08700.6 CDO77276.1 - 2e-06 27.5 0.3 7.7e-06 25.6 0.2 2.1 1 0 0 1 1 1 1 Vps51/Vps67 DUF2450 PF10475.4 CDO77276.1 - 0.00049 19.1 0.1 0.00082 18.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 CDO77276.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 Baculo_PEP_C PF04513.7 CDO77276.1 - 0.36 10.6 9.3 0.03 14.1 1.0 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RPAP3_C PF13877.1 CDO77276.1 - 1.1 9.2 5.9 17 5.4 0.1 3.3 3 1 0 3 3 3 0 Potential Monad-binding region of RPAP3 FdhE PF04216.7 CDO77276.1 - 5.9 6.5 8.3 0.76 9.4 2.0 2.1 2 1 0 2 2 2 0 Protein involved in formate dehydrogenase formation Sugar_tr PF00083.19 CDO77278.1 - 1.6e-119 399.4 12.8 2e-119 399.1 8.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO77278.1 - 1.3e-16 60.2 35.2 1.5e-12 46.9 9.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3149 PF11346.3 CDO77278.1 - 0.32 10.5 5.5 0.19 11.3 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Dus PF01207.12 CDO77279.1 - 1.3e-48 165.4 0.0 1.7e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiC PF01964.13 CDO77279.1 - 0.076 11.5 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 ThiC family Inositol_P PF00459.20 CDO77280.1 - 7.6e-66 222.1 0.0 8.9e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Proteasome PF00227.21 CDO77281.1 - 8.2e-56 188.3 0.0 1.1e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDO77281.1 - 2e-14 52.5 0.0 3.6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Rotamase PF00639.16 CDO77282.1 - 2.1e-25 89.2 0.0 2.7e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CDO77282.1 - 5.9e-23 81.3 0.0 6.7e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CDO77282.1 - 1.2e-07 31.5 0.2 2.4e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 CDO77282.1 - 5.5e-06 27.0 0.0 7.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain PEP_mutase PF13714.1 CDO77283.1 - 3.3e-15 55.9 0.0 4.1e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase CAGE1 PF15066.1 CDO77283.1 - 0.069 11.5 0.0 0.092 11.1 0.0 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family MOSC PF03473.12 CDO77284.1 - 0.00015 21.2 0.0 0.011 15.2 0.0 2.3 1 1 0 1 1 1 1 MOSC domain Ribonuc_L-PSP PF01042.16 CDO77285.1 - 2.8e-41 140.0 0.3 7.6e-41 138.6 0.1 1.8 2 0 0 2 2 2 1 Endoribonuclease L-PSP K_channel_TID PF07941.6 CDO77286.1 - 3.2 8.0 6.3 0.2 11.8 0.5 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Pkinase PF00069.20 CDO77287.1 - 0.078 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Nnf1 PF03980.9 CDO77288.1 - 0.096 12.6 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 Nnf1 CENP-F_leu_zip PF10473.4 CDO77288.1 - 0.15 11.9 1.4 0.24 11.2 0.1 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.8 CDO77288.1 - 0.2 12.0 2.7 16 6.0 0.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Hamartin PF04388.7 CDO77288.1 - 0.7 8.4 6.1 0.82 8.2 4.2 1.2 1 0 0 1 1 1 0 Hamartin protein DUF1688 PF07958.6 CDO77290.1 - 3.5e-164 546.3 0.0 3.9e-164 546.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) SLH PF00395.15 CDO77291.1 - 0.12 12.1 0.0 3.5 7.4 0.0 2.6 2 0 0 2 2 2 0 S-layer homology domain Vps51 PF08700.6 CDO77292.1 - 3.4e-16 58.8 0.7 9.8e-16 57.3 0.5 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 CDO77292.1 - 0.00054 19.8 1.6 0.00054 19.8 1.1 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 efThoc1 PF11957.3 CDO77293.1 - 1.1e-99 334.2 1.7 7e-95 318.3 0.1 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Tuberin PF03542.11 CDO77293.1 - 0.26 10.2 0.0 0.43 9.5 0.0 1.2 1 0 0 1 1 1 0 Tuberin Epimerase PF01370.16 CDO77294.1 - 8e-41 140.0 0.0 1.1e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CDO77294.1 - 9.5e-27 92.7 0.0 1.6e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CDO77294.1 - 1.8e-12 46.5 0.0 6e-12 44.8 0.0 1.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CDO77294.1 - 4.9e-11 42.0 0.1 2.7e-10 39.6 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 CDO77294.1 - 7e-11 41.5 0.1 1.7e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CDO77294.1 - 8e-10 38.0 0.0 1.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CDO77294.1 - 2.8e-09 37.1 0.0 5.9e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO77294.1 - 1.2e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CDO77294.1 - 0.0042 17.1 0.0 0.053 13.5 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CDO77294.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain YcfA PF07927.7 CDO77294.1 - 0.062 13.2 0.2 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 YcfA-like protein DapB_N PF01113.15 CDO77294.1 - 0.1 12.5 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 CDO77294.1 - 0.14 11.3 0.1 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family MFS_1 PF07690.11 CDO77295.1 - 4.3e-12 45.4 36.4 9e-11 41.0 9.7 3.1 1 1 2 3 3 3 2 Major Facilitator Superfamily COX8 PF02285.10 CDO77295.1 - 0.27 10.8 2.0 0.65 9.5 1.4 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII G-alpha PF00503.15 CDO77298.1 - 1.7e-116 389.1 0.0 2.2e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CDO77298.1 - 6.2e-14 51.6 0.6 6.6e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 CDO77298.1 - 0.0016 17.9 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DAP3 PF10236.4 CDO77298.1 - 0.01 14.8 0.2 0.018 14.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Gtr1_RagA PF04670.7 CDO77298.1 - 0.021 13.9 0.1 4.7 6.2 0.1 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDO77298.1 - 0.026 13.9 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.17 CDO77298.1 - 0.18 11.2 0.1 23 4.3 0.0 2.5 2 1 0 2 2 2 0 Ras family DUF1805 PF08827.6 CDO77299.1 - 0.23 11.2 2.3 4 7.3 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) FG-GAP_2 PF14312.1 CDO77299.1 - 0.32 11.0 2.0 0.46 10.5 0.1 2.3 3 0 0 3 3 3 0 FG-GAP repeat Peptidase_S64 PF08192.6 CDO77302.1 - 0.41 8.9 2.7 0.48 8.6 1.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 SNF2_N PF00176.18 CDO77303.1 - 7e-76 254.8 1.0 7.9e-76 254.6 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 CDO77303.1 - 2e-41 140.3 0.7 2e-41 140.3 0.5 2.6 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 CDO77303.1 - 3.1e-28 98.4 1.9 3.1e-28 98.4 1.4 3.0 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 CDO77303.1 - 3.7e-15 55.5 0.0 1.3e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDO77303.1 - 1.5e-07 31.4 3.6 3.4e-07 30.2 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CDO77303.1 - 1.9e-07 30.2 0.0 1.9e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CDO77303.1 - 5.8e-07 29.1 0.0 1.8e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 CDO77303.1 - 0.002 18.0 0.5 0.012 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain DBINO PF13892.1 CDO77303.1 - 0.0036 17.3 5.2 0.0036 17.3 3.6 4.1 4 0 0 4 4 4 1 DNA-binding domain DEAD_2 PF06733.10 CDO77303.1 - 0.025 14.0 0.0 0.067 12.5 0.0 1.7 1 0 0 1 1 1 0 DEAD_2 Cohesin_load PF10345.4 CDO77305.1 - 5.3e-07 28.2 0.8 0.021 13.0 0.3 3.2 2 1 0 2 2 2 2 Cohesin loading factor IF4E PF01652.13 CDO77309.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E Glyco_hydro_47 PF01532.15 CDO77310.1 - 3.7e-151 503.8 0.0 4.3e-151 503.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 C5-epim_C PF06662.8 CDO77310.1 - 0.0027 17.0 0.0 4.7 6.4 0.0 3.3 3 0 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.8 CDO77310.1 - 0.04 12.9 0.1 2.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 CDO77310.1 - 0.042 12.1 0.1 0.87 7.7 0.0 2.1 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) IF-2B PF01008.12 CDO77311.1 - 9.4e-57 192.1 0.0 1.2e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family SLT PF01464.15 CDO77312.1 - 6.1e-13 48.3 0.0 1.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 CDO77312.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Lysozyme-like Metallophos PF00149.23 CDO77313.1 - 6.8e-29 100.6 0.1 4.8e-21 75.0 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CDO77313.1 - 1.9e-21 75.4 7.9 3.4e-13 49.0 1.2 2.5 1 1 1 2 2 2 2 TPR repeat PPP5 PF08321.7 CDO77313.1 - 7.4e-16 57.9 0.0 2e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.23 CDO77313.1 - 5.6e-14 51.0 11.6 3e-08 32.9 0.6 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CDO77313.1 - 4.3e-11 42.0 1.9 0.00019 21.3 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDO77313.1 - 4.5e-09 35.5 12.4 4.8e-05 22.9 0.4 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDO77313.1 - 3.1e-07 30.8 1.0 0.023 15.3 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDO77313.1 - 3.8e-06 27.1 3.7 0.0055 17.0 0.9 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDO77313.1 - 7.6e-06 25.6 0.3 0.0018 18.0 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDO77313.1 - 1.1e-05 25.6 3.1 0.037 14.6 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CDO77313.1 - 1.6e-05 24.3 5.0 2.1e-05 23.9 0.4 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDO77313.1 - 0.00081 19.2 1.8 0.0082 16.0 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDO77313.1 - 0.00097 19.4 4.8 0.0065 16.8 0.6 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CDO77313.1 - 0.021 14.9 6.4 0.043 13.9 2.9 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CDO77313.1 - 0.021 14.5 2.2 1 9.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.17 CDO77314.1 - 7.7e-09 35.0 0.0 0.00077 19.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 CDO77314.1 - 7.1e-08 31.9 0.1 2e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 CDO77314.1 - 7.1e-06 25.9 0.0 2.2e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO77314.1 - 0.076 12.8 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.24 CDO77315.1 - 4e-76 250.5 31.0 5.4e-14 51.5 0.6 12.4 11 2 0 11 11 11 8 KH domain KH_3 PF13014.1 CDO77315.1 - 1.3e-61 203.4 16.8 4e-10 39.1 0.2 12.2 13 0 0 13 13 13 9 KH domain KH_2 PF07650.12 CDO77315.1 - 6.7e-12 44.7 18.3 0.0045 16.5 0.1 8.4 7 3 1 8 8 8 5 KH domain SLS PF14611.1 CDO77315.1 - 1.5e-09 37.5 11.8 0.014 14.7 0.0 7.1 6 2 2 8 8 8 4 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 CDO77315.1 - 0.00011 21.7 2.9 0.28 10.8 0.0 5.4 5 0 0 5 5 5 1 KH domain Alkyl_sulf_C PF14864.1 CDO77315.1 - 0.012 15.5 0.6 4.7 7.2 0.0 3.2 3 0 0 3 3 3 0 Alkyl sulfatase C-terminal BMC PF00936.14 CDO77315.1 - 0.7 9.6 14.0 38 4.0 0.2 6.9 7 0 0 7 7 7 0 BMC domain ERO1 PF04137.10 CDO77316.1 - 4.6e-90 302.1 0.0 1.9e-85 287.0 0.0 2.1 1 1 1 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ShK PF01549.19 CDO77316.1 - 0.056 13.8 0.3 0.24 11.8 0.2 2.0 1 0 0 1 1 1 0 ShK domain-like Pox_A21 PF05323.7 CDO77317.1 - 0.27 11.6 0.3 0.56 10.6 0.2 1.5 1 0 0 1 1 1 0 Poxvirus A21 Protein ATP-sulfurylase PF01747.12 CDO77318.1 - 1.7e-86 288.9 0.5 2.4e-86 288.4 0.3 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 CDO77318.1 - 3.6e-52 175.9 0.0 6.7e-52 175.1 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 CDO77318.1 - 1.1e-38 132.3 0.0 1.7e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CDO77318.1 - 1.5e-05 24.9 0.5 3.2e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CDO77318.1 - 0.0003 21.5 0.0 0.0011 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDO77318.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CDO77318.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.17 CDO77318.1 - 0.027 13.9 0.7 0.05 13.0 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 CDO77318.1 - 0.027 13.9 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 CDO77318.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ArgK PF03308.11 CDO77318.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein UPF0079 PF02367.12 CDO77318.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Asp PF00026.18 CDO77319.1 - 1e-23 84.1 0.0 4.2e-22 78.8 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CDO77319.1 - 0.0052 17.2 0.2 0.45 11.0 0.1 2.8 2 0 0 2 2 2 1 Aspartyl protease DUF912 PF06024.7 CDO77319.1 - 0.034 14.2 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1049 PF06305.6 CDO77319.1 - 0.052 13.0 0.5 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Asp PF00026.18 CDO77320.1 - 3e-14 53.0 0.2 3.5e-08 33.0 0.0 2.9 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CDO77320.1 - 0.00011 22.5 1.5 0.0011 19.3 0.4 2.6 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 CDO77320.1 - 0.073 13.0 0.8 0.51 10.2 0.1 2.5 2 1 1 3 3 3 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CDO77320.1 - 0.15 11.9 0.3 0.56 10.0 0.0 2.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease SNF2_N PF00176.18 CDO77321.1 - 7e-51 172.7 1.0 7e-51 172.7 0.7 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 CDO77321.1 - 3.7e-25 88.0 0.7 1.3e-24 86.2 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.19 CDO77321.1 - 8.5e-18 63.7 4.3 1.5e-14 53.4 0.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CDO77321.1 - 1.1e-09 37.9 0.0 2.8e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TBP PF00352.16 CDO77321.1 - 0.00027 20.2 0.0 0.00096 18.4 0.0 1.9 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) ResIII PF04851.10 CDO77321.1 - 0.0078 16.0 0.0 0.054 13.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.26 CDO77321.1 - 0.025 14.6 0.0 0.07 13.2 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3353 PF11833.3 CDO77322.1 - 0.012 15.1 0.3 0.015 14.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) CRPA PF05745.6 CDO77322.1 - 0.25 11.1 1.8 0.17 11.6 0.2 1.5 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Slu7 PF11708.3 CDO77323.1 - 4.5e-85 285.2 14.5 4.5e-85 285.2 10.0 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor DUF2151 PF10221.4 CDO77323.1 - 0.029 12.5 5.6 0.055 11.6 0.8 2.1 2 0 0 2 2 2 0 Cell cycle and development regulator zf-CCHC_4 PF14392.1 CDO77323.1 - 0.046 13.3 0.7 0.098 12.3 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Baculo_ODV-E27 PF05314.6 CDO77323.1 - 0.16 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 Pkinase PF00069.20 CDO77324.1 - 2.1e-59 200.7 0.0 2.6e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77324.1 - 2.5e-35 121.7 0.0 3.3e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO77324.1 - 1.2e-05 24.4 0.0 3.3e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RNase_H2-Ydr279 PF09468.5 CDO77326.1 - 1.3e-48 165.8 0.5 2e-48 165.1 0.3 1.2 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Imm47 PF15586.1 CDO77326.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 47 MmgE_PrpD PF03972.9 CDO77327.1 - 1.6e-159 530.8 0.0 2e-159 530.5 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Zn_clus PF00172.13 CDO77328.1 - 9.6e-08 31.8 7.8 1.6e-07 31.1 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 CDO77328.1 - 0.0054 15.7 6.6 0.0057 15.7 4.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Macoilin PF09726.4 CDO77328.1 - 2.7 6.1 7.8 3.6 5.7 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Cyclin PF08613.6 CDO77329.1 - 1.4e-08 35.3 0.0 1.5e-06 28.7 0.0 2.3 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.18 CDO77329.1 - 0.0031 17.0 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Asp PF00026.18 CDO77331.1 - 2.5e-43 148.5 2.5 5e-43 147.5 1.8 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO77331.1 - 1e-06 28.8 1.2 1.5e-05 25.0 0.6 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CDO77331.1 - 0.0091 15.5 0.1 0.3 10.5 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CDO77331.1 - 0.015 15.8 2.3 6 7.4 0.0 3.4 2 1 0 2 2 2 0 Aspartyl protease Sipho_Gp37 PF14594.1 CDO77331.1 - 0.015 14.5 0.1 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 Siphovirus ReqiPepy6 Gp37-like protein Acetyltransf_1 PF00583.19 CDO77333.1 - 2.3e-15 56.3 0.0 3.2e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDO77333.1 - 1.3e-10 41.3 0.2 2.2e-10 40.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CDO77333.1 - 1.1e-08 35.2 0.0 1.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDO77333.1 - 1.5e-06 28.3 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CDO77333.1 - 8.1e-05 22.5 0.0 0.0001 22.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDO77333.1 - 0.00038 20.1 0.0 0.0007 19.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 CDO77333.1 - 0.0006 20.0 0.0 0.00071 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Lipid_bd PF12888.2 CDO77333.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Lipid-binding putative hydrolase DUF3749 PF12568.3 CDO77333.1 - 0.026 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C2H2_4 PF13894.1 CDO77334.1 - 6.1e-10 38.7 5.5 0.00065 19.8 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CDO77334.1 - 3.8e-09 36.3 6.8 4e-07 29.9 0.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CDO77334.1 - 2.3e-07 30.7 15.7 0.00015 21.9 0.8 3.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CDO77334.1 - 0.19 11.9 0.4 0.19 11.9 0.3 4.4 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding DNA_ligase_A_M PF01068.16 CDO77335.1 - 1.6e-38 132.1 0.0 7.5e-36 123.3 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CDO77335.1 - 9.6e-36 123.2 0.0 1.9e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CDO77335.1 - 1.4e-19 70.3 0.0 3.8e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Asp_protease_2 PF13650.1 CDO77338.1 - 0.01 16.3 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.5 CDO77338.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease p450 PF00067.17 CDO77341.1 - 1.7e-06 26.8 0.0 2e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAM176 PF14851.1 CDO77342.1 - 2.1 8.0 5.5 0.99 9.0 1.5 1.9 2 0 0 2 2 2 0 FAM176 family DUF3439 PF11921.3 CDO77342.1 - 3.3 7.4 6.6 6.1 6.6 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pro-kuma_activ PF09286.6 CDO77343.1 - 1.4e-39 135.3 0.0 1.4e-36 125.6 0.0 2.2 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO77343.1 - 6.3e-08 32.1 0.3 1.2e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 Subtilase family UQ_con PF00179.21 CDO77345.1 - 9.1e-41 138.5 0.0 1.2e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CDO77345.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain RTA1 PF04479.8 CDO77347.1 - 2.6e-36 125.2 0.6 3.5e-36 124.7 0.4 1.1 1 0 0 1 1 1 1 RTA1 like protein O-ag_pol_Wzy PF14296.1 CDO77347.1 - 0.00027 19.6 0.1 0.00085 18.0 0.0 1.7 2 0 0 2 2 2 1 O-antigen polysaccharide polymerase Wzy Pkinase PF00069.20 CDO77348.1 - 0.00026 20.2 0.0 0.00045 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 CDO77348.1 - 0.00097 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CDO77348.1 - 0.0037 17.0 1.1 0.028 14.1 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CDO77348.1 - 0.038 13.0 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 CDO77348.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) MARVEL PF01284.18 CDO77349.1 - 0.0018 18.0 8.5 0.0027 17.5 5.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2339 PF10101.4 CDO77349.1 - 0.088 11.0 8.9 0.97 7.6 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) RTA1 PF04479.8 CDO77350.1 - 2.8e-41 141.4 3.2 4.4e-41 140.8 2.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Nrap PF03813.9 CDO77351.1 - 2.9e-227 756.6 0.0 5.6e-197 656.4 0.0 2.0 1 1 0 2 2 2 2 Nrap protein Cellulase PF00150.13 CDO77352.1 - 8.1e-13 48.2 0.0 5.5e-09 35.6 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DIOX_N PF14226.1 CDO77353.1 - 9.5e-14 51.9 0.0 1.9e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO77353.1 - 7.7e-12 45.3 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CDO77354.1 - 1.3e-15 57.9 0.0 2.6e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO77354.1 - 8.5e-14 51.6 0.0 1.7e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF461 PF04314.8 CDO77354.1 - 0.015 14.9 0.0 0.14 11.8 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF461) DIOX_N PF14226.1 CDO77355.1 - 1e-15 58.2 0.0 2.3e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO77355.1 - 1.2e-10 41.5 0.0 2.6e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tetraspannin PF00335.15 CDO77356.1 - 0.17 11.1 0.4 0.26 10.5 0.3 1.1 1 0 0 1 1 1 0 Tetraspanin family Lectin_N PF03954.9 CDO77356.1 - 0.2 11.0 2.1 0.16 11.3 0.4 1.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Aldedh PF00171.17 CDO77357.1 - 1.9e-55 188.0 0.0 3.1e-28 98.3 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 CDO77357.1 - 8.3e-05 21.4 0.0 0.11 11.1 0.0 2.3 2 1 0 2 2 2 2 Acyl-CoA reductase (LuxC) Aldedh PF00171.17 CDO77358.1 - 9.3e-60 202.2 0.0 9.5e-32 109.9 0.0 2.2 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 CDO77358.1 - 3.4e-05 22.7 0.0 0.02 13.6 0.0 2.3 1 1 1 2 2 2 2 Acyl-CoA reductase (LuxC) ATPase-cat_bd PF12156.3 CDO77359.1 - 0.14 12.7 0.3 0.26 11.8 0.2 1.4 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Peptidase_S10 PF00450.17 CDO77360.1 - 2.6e-63 214.6 3.3 7.5e-37 127.4 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase Peptidase_S10 PF00450.17 CDO77361.1 - 1.3e-75 255.1 0.0 1.6e-75 254.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2204 PF09970.4 CDO77362.1 - 1.8e-06 27.5 0.0 0.0028 17.1 0.0 2.4 2 0 0 2 2 2 2 Nucleotidyl transferase of unknown function (DUF2204) Defensin_propep PF00879.13 CDO77362.1 - 0.1 12.5 0.0 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Defensin propeptide TauD PF02668.11 CDO77363.1 - 1.1e-54 185.8 0.7 1.4e-54 185.4 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 CDO77363.1 - 0.00019 21.7 0.2 0.00074 19.8 0.1 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF971) Asp PF00026.18 CDO77364.1 - 1.6e-16 60.4 0.7 3.2e-15 56.1 0.5 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.18 CDO77365.1 - 2e-35 122.5 0.9 7.1e-35 120.7 0.6 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CDO77365.1 - 2.1e-06 28.1 3.5 3.4e-06 27.4 0.4 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO77365.1 - 0.011 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Plectin PF00681.15 CDO77365.1 - 0.028 13.9 0.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 Plectin repeat RVP PF00077.15 CDO77365.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease TAXi_N PF14543.1 CDO77365.1 - 0.06 13.2 0.8 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal DUF607 PF04678.8 CDO77366.1 - 2.4e-41 141.6 0.0 4.5e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF607 NT-C2 PF10358.4 CDO77367.1 - 1.7e-20 72.9 0.0 2.5e-19 69.2 0.0 2.1 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Asp PF00026.18 CDO77369.1 - 2.1e-44 152.0 9.8 4.7e-44 150.9 6.8 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO77369.1 - 0.00027 20.9 4.3 0.00039 20.4 0.6 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal UDPGT PF00201.13 CDO77370.1 - 4.8e-19 68.2 0.1 7.4e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 CDO77370.1 - 0.00053 19.6 0.1 0.00089 18.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CDO77370.1 - 0.0037 16.4 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 F-box-like PF12937.2 CDO77371.1 - 0.021 14.5 0.0 0.065 12.9 0.0 1.8 1 0 0 1 1 1 0 F-box-like UDPGT PF00201.13 CDO77372.1 - 1.1e-18 67.0 0.0 1.5e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Amidohydro_2 PF04909.9 CDO77372.1 - 0.00082 19.0 0.4 0.0016 18.0 0.2 1.5 1 1 0 1 1 1 1 Amidohydrolase Glyco_tran_28_C PF04101.11 CDO77372.1 - 0.0086 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CDO77372.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 Striatin PF08232.7 CDO77375.1 - 0.0014 18.9 0.1 0.0043 17.3 0.0 1.8 2 0 0 2 2 2 1 Striatin family PspA_IM30 PF04012.7 CDO77375.1 - 0.0067 15.8 0.8 0.013 14.8 0.6 1.4 1 0 0 1 1 1 1 PspA/IM30 family Rootletin PF15035.1 CDO77375.1 - 0.0069 16.3 0.8 0.0086 16.0 0.6 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.6 CDO77375.1 - 0.0097 15.7 0.8 0.019 14.7 0.6 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) BRICHOS PF04089.9 CDO77375.1 - 0.011 15.6 0.1 0.05 13.4 0.1 2.1 1 1 0 1 1 1 0 BRICHOS domain DivIC PF04977.10 CDO77375.1 - 0.012 15.0 4.2 0.035 13.5 2.9 1.7 1 1 1 2 2 2 0 Septum formation initiator IncA PF04156.9 CDO77375.1 - 0.014 14.9 1.3 0.022 14.3 0.9 1.3 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 CDO77375.1 - 0.039 13.7 3.1 0.064 13.0 2.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 CDO77375.1 - 0.041 13.8 2.3 0.084 12.8 1.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor DUF948 PF06103.6 CDO77375.1 - 0.044 13.6 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Herpes_UL6 PF01763.11 CDO77375.1 - 0.047 11.8 0.5 0.068 11.3 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF869 PF05911.6 CDO77375.1 - 0.05 11.8 1.2 0.069 11.3 0.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Tropomyosin_1 PF12718.2 CDO77375.1 - 0.05 13.4 2.8 0.087 12.6 2.0 1.3 1 0 0 1 1 1 0 Tropomyosin like Phlebovirus_NSM PF07246.6 CDO77375.1 - 0.065 12.3 0.2 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Sipho_Gp157 PF05565.6 CDO77375.1 - 0.066 12.8 0.3 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 DUF972 PF06156.8 CDO77375.1 - 0.094 13.0 2.2 0.15 12.4 1.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF972) KLRAQ PF10205.4 CDO77375.1 - 0.098 12.7 2.1 0.21 11.6 1.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein TBPIP PF07106.8 CDO77375.1 - 0.13 11.8 2.0 0.21 11.1 1.4 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IFP_35_N PF07334.8 CDO77375.1 - 0.16 11.9 1.2 0.33 10.9 0.8 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF904 PF06005.7 CDO77375.1 - 0.17 12.1 9.0 0.044 14.0 4.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF3186 PF11382.3 CDO77375.1 - 0.34 10.0 1.3 0.52 9.4 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) bZIP_2 PF07716.10 CDO77375.1 - 4.1 7.2 10.7 3 7.7 2.9 2.5 1 1 1 2 2 2 0 Basic region leucine zipper FAD_binding_3 PF01494.14 CDO77376.1 - 7.1e-05 22.0 0.1 7.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CDO77376.1 - 9.8e-05 22.3 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO77376.1 - 0.00022 20.2 0.1 0.00023 20.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CDO77376.1 - 0.0063 16.4 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CDO77376.1 - 0.016 14.1 0.2 0.021 13.6 0.1 1.3 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 CDO77376.1 - 0.018 15.4 0.1 0.026 14.9 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GST_N_3 PF13417.1 CDO77376.1 - 0.02 15.1 0.0 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Pyr_redox_3 PF13738.1 CDO77376.1 - 0.071 13.1 0.0 0.078 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CDO77376.1 - 0.077 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 CDO77376.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.3 1 1 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 CDO77376.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 CDO77377.1 - 1.5e-10 40.6 0.3 2e-10 40.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 CDO77377.1 - 0.011 14.5 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase Ribosomal_L24e PF01246.15 CDO77377.1 - 0.079 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L24e rve PF00665.21 CDO77378.1 - 2.1e-23 82.6 0.0 5.3e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 CDO77378.1 - 1.7e-15 56.6 0.0 3.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO77378.1 - 5.4e-11 42.3 0.0 8.8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO77378.1 - 2.2e-09 36.7 0.1 6e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CDO77378.1 - 0.00017 21.0 0.1 0.00047 19.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain BRF1 PF07741.8 CDO77378.1 - 2.5 8.3 5.8 11 6.2 0.7 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DDE_Tnp_4 PF13359.1 CDO77379.1 - 1.6e-22 79.8 0.0 1.9e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CDO77379.1 - 0.0034 16.7 0.1 0.0056 16.0 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 CDO77379.1 - 0.0097 15.4 0.1 0.038 13.5 0.1 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 CDO77379.1 - 0.02 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Pap_E4 PF02711.9 CDO77380.1 - 0.6 10.9 4.8 3.4 8.5 0.8 2.7 2 1 0 2 2 2 0 E4 protein Helicase_C PF00271.26 CDO77381.1 - 6.5e-21 73.9 0.1 1.4e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO77381.1 - 1e-16 60.9 0.0 4.9e-16 58.6 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CDO77381.1 - 0.061 13.4 0.4 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain TLP-20 PF06088.6 CDO77381.1 - 0.78 9.3 6.2 1.5 8.4 4.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FLO_LFY PF01698.11 CDO77381.1 - 2.6 6.7 7.2 4 6.1 5.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein YihI PF04220.7 CDO77382.1 - 0.63 9.3 9.5 1.2 8.4 6.6 1.4 1 0 0 1 1 1 0 Der GTPase activator (YihI) RAP1 PF07218.6 CDO77382.1 - 5.6 4.9 8.8 7.6 4.4 6.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AvrE PF11725.3 CDO77382.1 - 7.3 3.4 12.6 9.1 3.1 8.8 1.0 1 0 0 1 1 1 0 Pathogenicity factor FHA PF00498.21 CDO77383.1 - 1.1e-07 31.8 0.0 2.2e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 FHA domain G-patch PF01585.18 CDO77383.1 - 1.7e-07 30.8 0.0 2.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CDO77383.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 DExH-box splicing factor binding site Cyclin_N PF00134.18 CDO77384.1 - 5.6e-44 148.7 0.5 1.8e-43 147.1 0.2 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CDO77384.1 - 3.7e-25 88.1 0.0 7.3e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Acyl-CoA_dh_1 PF00441.19 CDO77385.1 - 8e-24 84.4 2.2 1.2e-23 83.8 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CDO77385.1 - 3.4e-17 61.6 0.8 5.8e-17 60.9 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 CDO77385.1 - 3e-13 49.3 0.0 8.1e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 CDO77385.1 - 7.2e-10 39.4 0.1 3.1e-09 37.3 0.0 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain UPF0061 PF02696.9 CDO77386.1 - 3.1e-57 194.0 0.0 1.2e-56 192.1 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Actin PF00022.14 CDO77387.1 - 2.2e-88 296.3 0.0 2.9e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Actin DUF1427 PF07235.6 CDO77388.1 - 1.5 8.9 3.9 2.1 8.5 0.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1427) APG17 PF04108.7 CDO77390.1 - 1.8e-28 99.4 23.2 5.4e-20 71.5 8.8 3.5 3 1 0 3 3 3 3 Autophagy protein Apg17 Sin3_corepress PF08295.7 CDO77390.1 - 0.089 12.5 3.3 0.17 11.6 0.1 3.0 3 0 0 3 3 3 0 Sin3 family co-repressor DUF148 PF02520.12 CDO77390.1 - 0.24 11.2 3.4 0.39 10.5 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function DUF148 NPV_P10 PF05531.7 CDO77390.1 - 0.32 11.2 8.0 5.2 7.3 0.6 4.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Exo_endo_phos PF03372.18 CDO77391.1 - 2.4e-10 40.7 0.3 1.3e-08 35.1 0.2 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CDO77391.1 - 0.012 15.1 0.0 0.1 12.2 0.0 2.2 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF1019 PF06254.6 CDO77392.1 - 0.094 12.8 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) TAP_C PF03943.8 CDO77394.1 - 3.1e-08 32.9 0.0 6.5e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 CDO77394.1 - 1.2e-06 27.9 0.1 0.0064 16.0 0.0 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) NTF2 PF02136.15 CDO77394.1 - 0.0002 21.7 0.0 1 9.7 0.0 2.3 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain UBA_4 PF14555.1 CDO77394.1 - 0.0048 16.3 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain LRR_8 PF13855.1 CDO77394.1 - 0.069 12.9 0.6 1.4 8.7 0.1 2.5 2 0 0 2 2 2 0 Leucine rich repeat LRR_7 PF13504.1 CDO77394.1 - 0.11 12.7 0.2 37 5.1 0.0 3.5 3 0 0 3 3 3 0 Leucine rich repeat Exo_endo_phos_2 PF14529.1 CDO77395.1 - 7.8e-09 35.1 0.2 1.6e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CDO77395.1 - 2e-07 31.1 1.8 4.3e-07 30.1 1.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF77 PF01910.12 CDO77395.1 - 0.022 14.4 0.1 0.062 12.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF77 Prenyltrans PF00432.16 CDO77395.1 - 0.027 14.0 1.5 0.067 12.7 1.0 1.7 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat RPN7 PF10602.4 CDO77396.1 - 6.7e-41 139.6 0.8 2.3e-40 137.8 0.5 2.0 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CDO77396.1 - 7.1e-17 61.6 1.5 2.1e-16 60.1 0.6 2.2 2 0 0 2 2 2 1 PCI domain Abhydrolase_6 PF12697.2 CDO77396.1 - 1.4e-07 31.6 0.1 2.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_2 PF07719.12 CDO77396.1 - 0.00084 19.0 0.1 2.1 8.4 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat PCI_Csn8 PF10075.4 CDO77396.1 - 0.0017 18.1 0.4 0.0048 16.6 0.3 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Abhydrolase_1 PF00561.15 CDO77396.1 - 0.0019 17.7 0.0 0.0044 16.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold TPR_1 PF00515.23 CDO77396.1 - 0.0024 17.4 0.2 0.39 10.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CDO77396.1 - 0.0065 16.0 0.3 0.66 9.6 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.1 CDO77396.1 - 0.0071 16.0 0.2 0.72 9.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDO77396.1 - 0.013 15.4 0.1 0.41 10.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 CDO77396.1 - 0.037 13.8 0.1 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2119 PF09892.4 CDO77396.1 - 0.061 12.5 0.5 0.14 11.4 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Pro_isomerase PF00160.16 CDO77397.1 - 1.7e-29 103.0 0.0 2.9e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DDE_3 PF13358.1 CDO77397.1 - 7e-15 55.0 1.8 7e-15 55.0 0.5 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.21 CDO77397.1 - 0.0097 16.0 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain LexA_DNA_bind PF01726.11 CDO77397.1 - 0.15 11.6 0.1 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain AMP-binding PF00501.23 CDO77398.1 - 8.9e-28 96.8 0.1 5.2e-26 90.9 0.0 2.7 2 1 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CDO77398.1 - 2.1e-27 95.6 0.0 3.3e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CDO77398.1 - 1.1e-10 41.4 0.0 1.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO77398.1 - 9.3e-05 21.2 0.0 0.0004 19.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 CDO77398.1 - 0.001 19.2 0.1 0.0037 17.5 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 CDO77398.1 - 0.0013 18.7 3.2 0.011 15.6 0.1 3.6 3 1 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 CDO77398.1 - 0.13 11.9 0.1 0.85 9.2 0.0 2.3 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.10 CDO77398.1 - 0.13 11.1 0.0 5.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 CDO77399.1 - 3e-23 81.8 0.0 6.2e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO77399.1 - 2.3e-08 34.9 0.0 7.1e-08 33.4 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 CDO77399.1 - 0.0022 17.9 0.0 0.0066 16.4 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CDO77399.1 - 0.021 14.4 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PALP PF00291.20 CDO77399.1 - 0.023 13.9 0.1 0.034 13.3 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme CAP59_mtransfer PF11735.3 CDO77401.1 - 6.3e-70 235.1 0.0 8.5e-70 234.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ion_trans PF00520.26 CDO77401.1 - 0.04 13.1 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Ion transport protein Ribosomal_L31e PF01198.14 CDO77402.1 - 6.3e-36 121.9 2.9 7.9e-36 121.6 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e CFEM PF05730.6 CDO77403.1 - 4.6e-10 39.1 12.5 6.9e-10 38.6 8.7 1.3 1 0 0 1 1 1 1 CFEM domain Pacs-1 PF10254.4 CDO77403.1 - 0.28 9.7 3.3 0.37 9.3 2.3 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Sporozoite_P67 PF05642.6 CDO77403.1 - 1.1 7.0 11.7 1.3 6.7 8.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Phosphoprotein PF00922.12 CDO77403.1 - 8.5 5.4 8.2 11 5.1 5.7 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein VIT1 PF01988.14 CDO77405.1 - 1.9e-30 105.9 0.7 2.3e-30 105.6 0.5 1.1 1 0 0 1 1 1 1 VIT family His_Phos_2 PF00328.17 CDO77406.1 - 0.011 15.1 0.1 0.43 9.8 0.0 2.5 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Isy1 PF06246.7 CDO77407.1 - 2.4e-65 220.4 0.5 5.3e-65 219.3 0.3 1.5 1 1 0 1 1 1 1 Isy1-like splicing family P22_Tail-4 PF11650.3 CDO77407.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P22 tail accessory factor Sugar_tr PF00083.19 CDO77411.1 - 8.8e-110 367.3 25.7 1e-109 367.1 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO77411.1 - 5.7e-28 97.6 29.0 5.7e-28 97.6 20.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO77411.1 - 1.6e-07 29.9 3.7 1.6e-07 29.9 2.5 2.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CDO77411.1 - 0.00019 19.7 5.8 0.00093 17.4 1.4 2.5 2 1 0 2 2 2 2 Transmembrane secretion effector AMP-binding PF00501.23 CDO77413.1 - 1.5e-31 109.2 0.0 7.9e-29 100.2 0.0 2.2 1 1 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 CDO77413.1 - 1.9e-28 99.0 0.0 3.3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CDO77413.1 - 9.5e-10 38.3 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 CDO77413.1 - 0.0032 17.7 0.0 0.0083 16.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 CDO77413.1 - 0.043 13.7 0.7 0.31 10.9 0.1 2.7 2 1 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CDO77413.1 - 0.064 12.1 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein JAB PF01398.16 CDO77414.1 - 6.8e-16 58.0 0.0 2.1e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CDO77414.1 - 3.5e-07 29.7 0.0 3.5e-07 29.7 0.0 2.9 3 1 0 3 3 3 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 CDO77414.1 - 6.2e-05 22.9 0.1 0.00016 21.5 0.0 1.8 2 0 0 2 2 2 1 USP8 dimerisation domain Borrelia_P83 PF05262.6 CDO77414.1 - 0.0097 14.2 9.3 0.013 13.7 6.5 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Glyco_transf_90 PF05686.7 CDO77415.1 - 5.8e-14 51.5 3.0 1e-11 44.1 1.3 3.7 3 1 0 3 3 3 2 Glycosyl transferase family 90 Molybdopterin PF00384.17 CDO77417.1 - 3.1e-69 233.8 0.0 1.6e-68 231.4 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 CDO77417.1 - 4.9e-19 67.2 0.1 1.2e-18 66.0 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 CDO77417.1 - 1.5e-16 60.2 0.1 4.2e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2_4 PF13510.1 CDO77417.1 - 5.9e-11 42.0 0.1 1.6e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 CDO77417.1 - 0.013 15.2 0.0 0.66 9.7 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4_15 PF13459.1 CDO77417.1 - 0.044 14.3 0.0 0.17 12.4 0.0 2.0 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4 PF00037.22 CDO77417.1 - 0.085 12.4 1.1 3.8 7.2 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 CDO77417.1 - 0.33 10.9 2.4 0.44 10.5 0.6 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain N2227 PF07942.7 CDO77418.1 - 2e-82 276.2 0.0 6.3e-82 274.5 0.0 1.7 1 1 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 CDO77418.1 - 0.00033 20.4 0.0 0.0017 18.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Nif11 PF07862.6 CDO77418.1 - 0.042 13.7 0.1 0.6 10.0 0.0 2.4 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function SelP_N PF04592.9 CDO77418.1 - 0.97 8.7 9.6 1.5 8.1 6.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 CDO77418.1 - 2.1 7.2 5.8 2.9 6.8 4.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ABC2_membrane PF01061.19 CDO77419.1 - 4.9e-79 264.3 64.4 3.8e-45 153.6 14.3 2.9 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 CDO77419.1 - 3.2e-40 137.5 0.0 8.6e-19 68.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CDO77419.1 - 1.2e-33 114.8 11.5 1.1e-29 102.1 0.0 2.8 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CDO77419.1 - 4.9e-15 55.3 0.0 9.8e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CDO77419.1 - 5.4e-08 32.4 0.0 0.00055 19.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 CDO77419.1 - 1.3e-06 27.6 0.0 9.8e-05 21.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CDO77419.1 - 3.1e-06 27.3 0.1 0.083 13.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CDO77419.1 - 3.8e-06 27.0 0.0 0.094 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CDO77419.1 - 1.4e-05 24.4 1.6 0.045 13.2 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_18 PF13238.1 CDO77419.1 - 2.7e-05 24.4 0.0 0.11 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CDO77419.1 - 8.1e-05 22.5 0.0 0.44 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 CDO77419.1 - 0.00026 20.9 0.7 0.9 9.4 0.5 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CDO77419.1 - 0.00031 21.5 0.0 0.42 11.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain ABC2_membrane_3 PF12698.2 CDO77419.1 - 0.00041 19.4 45.8 0.013 14.6 10.4 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein MMR_HSR1 PF01926.18 CDO77419.1 - 0.00046 20.1 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 CDO77419.1 - 0.00075 19.1 0.8 0.65 9.6 0.1 3.2 3 0 0 3 3 3 1 NACHT domain cobW PF02492.14 CDO77419.1 - 0.00095 18.6 0.7 0.23 10.9 0.4 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 CDO77419.1 - 0.0022 17.4 0.3 3 7.1 0.2 3.1 3 0 0 3 3 3 1 AAA-like domain SbcCD_C PF13558.1 CDO77419.1 - 0.0026 17.6 0.0 0.8 9.6 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 CDO77419.1 - 0.0029 17.6 0.0 1.2 9.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CDO77419.1 - 0.0029 17.3 0.8 1.5 8.6 0.3 2.8 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 CDO77419.1 - 0.003 17.2 0.0 0.39 10.3 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase SMC_N PF02463.14 CDO77419.1 - 0.0046 16.2 0.1 0.16 11.1 0.0 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 CDO77419.1 - 0.0083 15.6 0.2 1.4 8.3 0.2 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 CDO77419.1 - 0.013 15.1 0.6 0.49 10.0 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 CDO77419.1 - 0.021 15.3 0.0 9.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 CDO77419.1 - 0.033 14.3 0.1 14 5.9 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 CDO77419.1 - 0.034 13.6 0.1 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.9 CDO77419.1 - 0.096 12.4 0.1 5.4 6.7 0.2 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CDO77419.1 - 0.19 11.4 0.1 23 4.6 0.1 3.0 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.1 CDO77419.1 - 0.21 11.8 0.1 0.58 10.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_15 PF13175.1 CDO77419.1 - 1.2 8.1 0.0 2.1 7.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Chitin_synth_2 PF03142.10 CDO77420.1 - 4.9e-241 800.7 0.3 7.6e-241 800.0 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CDO77420.1 - 8.4e-164 546.3 0.0 1.4e-163 545.6 0.0 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 CDO77420.1 - 4.1e-18 64.9 2.2 1.8e-17 62.8 1.2 2.2 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 CDO77420.1 - 2.1e-15 56.2 0.0 1.1e-08 34.6 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 CDO77420.1 - 7.5e-15 55.3 0.0 4.5e-12 46.2 0.0 2.8 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CDO77420.1 - 1.7e-14 53.9 5.6 1.7e-14 53.9 3.9 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CDO77420.1 - 0.00037 20.2 0.0 0.044 13.4 0.0 3.1 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CDO77420.1 - 0.031 13.5 0.4 0.17 11.1 0.0 2.3 3 0 0 3 3 3 0 Glycosyl transferase family 21 DDE_3 PF13358.1 CDO77421.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO77421.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Cu-oxidase_3 PF07732.10 CDO77422.1 - 4.1e-41 139.4 5.2 8.2e-40 135.2 2.2 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 CDO77422.1 - 5.4e-33 114.1 0.0 1.1e-32 113.1 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CDO77422.1 - 2e-25 88.9 12.9 4.5e-23 81.2 2.1 3.7 2 2 0 2 2 2 2 Multicopper oxidase ATP1G1_PLM_MAT8 PF02038.11 CDO77422.1 - 0.22 10.5 3.7 0.66 9.0 1.1 2.3 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Phosphoesterase PF04185.9 CDO77423.1 - 3e-25 89.2 7.2 5.8e-25 88.2 5.0 1.4 1 1 0 1 1 1 1 Phosphoesterase family Serglycin PF04360.7 CDO77423.1 - 0.0054 16.4 2.1 0.014 15.1 1.4 1.6 1 0 0 1 1 1 1 Serglycin ABC_membrane PF00664.18 CDO77424.1 - 1.8e-69 234.2 21.9 4.2e-37 128.0 2.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CDO77424.1 - 1e-65 220.1 0.0 3e-31 108.5 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 CDO77424.1 - 4.3e-15 55.5 6.7 8.5e-06 25.1 0.7 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDO77424.1 - 5.4e-11 42.9 0.0 0.012 15.5 0.0 4.2 3 1 0 4 4 4 2 AAA domain ABC_ATPase PF09818.4 CDO77424.1 - 2.6e-10 39.4 0.4 0.00045 18.9 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 CDO77424.1 - 7e-10 39.7 0.0 0.00061 20.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CDO77424.1 - 3.6e-09 36.8 2.3 0.004 17.2 0.1 4.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CDO77424.1 - 1.8e-08 34.5 5.9 0.0003 20.8 0.2 3.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 CDO77424.1 - 3.5e-08 33.2 3.2 0.022 14.1 0.1 4.1 3 1 0 4 4 4 2 AAA-like domain DUF87 PF01935.12 CDO77424.1 - 2.2e-07 30.9 0.2 0.0084 15.9 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function DUF87 AAA_18 PF13238.1 CDO77424.1 - 4.1e-07 30.3 0.0 0.0088 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CDO77424.1 - 6.8e-07 28.7 0.1 0.026 14.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CDO77424.1 - 7.8e-07 28.6 0.1 0.002 17.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 CDO77424.1 - 1.2e-06 27.8 0.0 0.043 13.0 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 CDO77424.1 - 2.3e-06 27.1 0.1 1.9 7.8 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein SbcCD_C PF13558.1 CDO77424.1 - 3e-06 27.0 0.5 0.16 11.9 0.1 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 CDO77424.1 - 3.4e-06 26.3 0.0 0.065 12.3 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin AAA_5 PF07728.9 CDO77424.1 - 1.2e-05 25.0 0.1 0.54 9.9 0.0 3.8 3 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CDO77424.1 - 1.4e-05 25.0 0.0 0.4 10.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CDO77424.1 - 1.4e-05 24.7 2.2 0.38 10.5 0.0 4.8 5 0 0 5 5 5 2 Part of AAA domain AAA_33 PF13671.1 CDO77424.1 - 4.4e-05 23.3 3.7 0.07 13.0 0.0 3.4 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 CDO77424.1 - 0.00033 20.7 0.0 0.97 9.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 CDO77424.1 - 0.00065 18.9 0.0 0.69 9.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CDO77424.1 - 0.00076 19.4 1.7 1.2 9.1 0.0 3.7 3 1 0 3 3 2 1 AAA domain NACHT PF05729.7 CDO77424.1 - 0.001 18.7 0.2 0.61 9.7 0.0 3.0 3 0 0 3 3 2 1 NACHT domain AAA PF00004.24 CDO77424.1 - 0.0013 18.9 0.1 2.1 8.5 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 CDO77424.1 - 0.0016 17.9 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 CDO77424.1 - 0.0017 18.0 0.0 1.4 8.5 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 CDO77424.1 - 0.003 16.3 0.0 0.74 8.4 0.0 2.7 2 1 0 2 2 2 1 G-protein alpha subunit CbiA PF01656.18 CDO77424.1 - 0.0043 16.4 0.0 1.5 8.2 0.0 2.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.15 CDO77424.1 - 0.0044 16.7 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase NB-ARC PF00931.17 CDO77424.1 - 0.0044 15.9 0.0 0.45 9.3 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain PRK PF00485.13 CDO77424.1 - 0.0065 16.0 0.0 0.33 10.4 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 CDO77424.1 - 0.0093 16.4 0.0 9 6.8 0.0 3.0 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 CDO77424.1 - 0.015 14.8 0.0 1.9 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 CDO77424.1 - 0.015 15.5 0.1 7.9 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.1 CDO77424.1 - 0.02 14.9 0.1 6.9 6.7 0.0 3.2 4 0 0 4 4 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.18 CDO77424.1 - 0.023 14.6 0.0 13 5.7 0.0 3.4 4 0 0 4 4 3 0 50S ribosome-binding GTPase PhoH PF02562.11 CDO77424.1 - 0.067 12.4 0.4 9.5 5.3 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein KaiC PF06745.8 CDO77424.1 - 0.067 12.2 0.1 13 4.8 0.0 2.6 2 0 0 2 2 2 0 KaiC Dynamin_N PF00350.18 CDO77424.1 - 0.24 11.1 0.5 12 5.6 0.0 2.8 2 0 0 2 2 2 0 Dynamin family AAA_13 PF13166.1 CDO77424.1 - 0.79 8.1 0.0 18 3.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.2 CDO77425.1 - 2.2e-09 36.8 0.6 2.2e-09 36.8 0.4 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDO77425.1 - 0.0068 16.0 0.5 0.036 13.7 0.4 2.3 1 1 0 1 1 1 1 F-box domain DUF639 PF04842.7 CDO77425.1 - 0.09 10.9 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) PTPA PF03095.10 CDO77426.1 - 1.8e-118 395.1 0.0 2.2e-118 394.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Retrotrans_gag PF03732.12 CDO77426.1 - 0.11 12.6 0.0 0.93 9.6 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein SURF6 PF04935.7 CDO77427.1 - 4.1e-39 134.0 42.2 4.1e-39 134.0 29.3 2.9 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 CDO77427.1 - 6.5e-22 77.3 11.0 6.5e-22 77.3 7.6 5.6 4 2 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 PAP2 PF01569.16 CDO77428.1 - 1.6e-11 43.9 6.6 1.6e-11 43.9 4.6 2.7 3 0 0 3 3 3 1 PAP2 superfamily Cation_efflux PF01545.16 CDO77428.1 - 4.4e-10 39.1 0.6 1.1e-09 37.7 0.4 1.6 1 0 0 1 1 1 1 Cation efflux family DUF212 PF02681.9 CDO77428.1 - 0.0094 15.6 0.0 0.031 13.9 0.0 1.9 1 0 0 1 1 1 1 Divergent PAP2 family Glyco_hydro_38 PF01074.17 CDO77429.1 - 0.053 12.7 0.7 0.11 11.7 0.5 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain ERG2_Sigma1R PF04622.7 CDO77429.1 - 0.18 11.0 1.4 0.24 10.6 0.1 1.8 2 0 0 2 2 2 0 ERG2 and Sigma1 receptor like protein BBS2_C PF14782.1 CDO77431.1 - 1.4 7.3 0.1 2.1 6.7 0.1 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal zf-rbx1 PF12678.2 CDO77433.1 - 2.1e-34 117.4 13.7 2.7e-34 117.1 9.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CDO77433.1 - 1.1e-16 60.3 9.4 1.5e-16 59.9 6.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CDO77433.1 - 1.6e-06 27.8 12.8 8.1e-06 25.5 8.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CDO77433.1 - 0.001 18.7 11.8 0.02 14.5 8.2 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO77433.1 - 0.0039 16.8 10.1 0.46 10.1 7.2 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDO77433.1 - 0.04 13.9 12.2 0.052 13.5 5.5 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CDO77433.1 - 0.12 12.3 9.0 0.76 9.7 6.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CDO77433.1 - 1.1 9.0 7.1 1.2 8.9 1.6 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 CDO77433.1 - 1.2 9.1 9.9 4.1 7.4 6.9 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 CDO77433.1 - 1.4 8.7 11.0 8.3 6.2 7.6 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 CDO77433.1 - 2.4 8.3 11.0 1e+02 3.1 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain TBCC PF07986.7 CDO77434.1 - 3e-23 81.5 0.7 5.1e-23 80.7 0.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF4023 PF13215.1 CDO77434.1 - 0.016 14.9 0.1 0.036 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) DUF4164 PF13747.1 CDO77434.1 - 0.44 10.7 2.1 1.9 8.6 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) F-box-like PF12937.2 CDO77435.1 - 0.22 11.2 4.3 0.15 11.7 0.4 2.7 2 0 0 2 2 2 0 F-box-like STAG PF08514.6 CDO77437.1 - 9e-30 102.8 0.2 9.1e-29 99.5 0.1 2.8 1 1 1 2 2 2 1 STAG domain DUF4200 PF13863.1 CDO77437.1 - 0.0019 18.1 4.4 0.0077 16.1 3.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) CRC_subunit PF08624.5 CDO77438.1 - 1.2e-10 41.4 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit IncA PF04156.9 CDO77439.1 - 9.5 5.7 10.7 0.58 9.7 3.7 1.7 2 0 0 2 2 2 0 IncA protein SAP PF02037.22 CDO77441.1 - 7.5e-06 25.3 0.5 7.5e-06 25.3 0.4 2.1 2 0 0 2 2 2 1 SAP domain LETM1 PF07766.8 CDO77441.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 LETM1-like protein TIMELESS PF04821.9 CDO77442.1 - 1.7e-52 178.2 0.3 5.4e-52 176.6 0.0 2.0 2 0 0 2 2 2 1 Timeless protein AMP-binding PF00501.23 CDO77444.1 - 5.1e-96 321.6 0.1 8.3e-96 320.9 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CDO77444.1 - 6.3e-22 78.3 0.3 2.7e-21 76.2 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2461 PF09365.5 CDO77445.1 - 4.7e-50 169.9 0.0 7.2e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Peroxin-3 PF04882.7 CDO77446.1 - 4.4e-76 256.3 0.0 5.2e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 GFO_IDH_MocA PF01408.17 CDO77448.1 - 2.2e-14 53.9 0.2 3.5e-14 53.3 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 CDO77448.1 - 0.0023 18.2 0.3 0.004 17.5 0.2 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Glyco_trans_1_4 PF13692.1 CDO77448.1 - 0.037 14.1 0.1 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Qn_am_d_aIII PF09099.5 CDO77448.1 - 0.07 13.4 0.0 2.3 8.6 0.0 2.4 2 1 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Glyco_hydro_1 PF00232.13 CDO77449.1 - 1.3e-149 498.3 1.1 5.3e-148 492.9 0.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 CDO77449.1 - 0.046 13.1 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Seryl_tRNA_N PF02403.17 CDO77450.1 - 0.14 12.1 0.3 0.27 11.2 0.0 1.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1843 PF08898.5 CDO77450.1 - 0.49 10.4 4.6 0.2 11.6 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) PI-PLC-X PF00388.14 CDO77451.1 - 1.1e-51 174.1 0.0 2.8e-51 172.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CDO77451.1 - 1.4e-40 137.9 0.0 2.7e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 CDO77451.1 - 2.6e-08 33.7 0.2 0.0059 16.6 0.0 3.4 3 0 0 3 3 3 2 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 CDO77451.1 - 1.4e-07 31.2 0.0 5e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 CDO77451.1 - 2.7e-05 24.1 8.8 0.00069 19.6 1.9 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CDO77451.1 - 0.0031 16.7 2.9 0.047 13.0 0.2 2.9 2 0 0 2 2 2 1 EF hand EF-hand_10 PF14788.1 CDO77451.1 - 0.015 14.9 0.2 0.039 13.6 0.1 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 CDO77451.1 - 0.078 12.9 8.9 1.2 9.2 0.6 3.7 3 0 0 3 3 3 0 EF-hand domain PAS PF00989.19 CDO77452.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold RVT_1 PF00078.22 CDO77453.1 - 7.7e-19 67.9 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO77453.1 - 2.1e-13 50.7 0.0 3.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO77453.1 - 0.024 14.9 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DDE_3 PF13358.1 CDO77454.1 - 2e-12 47.0 0.0 2.4e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 CDO77455.1 - 1.8e-14 53.7 0.4 2e-14 53.5 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO77455.1 - 0.013 15.5 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain Exonuc_VII_S PF02609.11 CDO77456.1 - 0.23 11.2 1.6 0.56 10.0 0.4 2.0 2 0 0 2 2 2 0 Exonuclease VII small subunit Exo_endo_phos_2 PF14529.1 CDO77457.1 - 0.00015 21.3 0.1 0.0018 17.8 0.1 2.0 1 1 1 2 2 2 1 Endonuclease-reverse transcriptase UBN2_2 PF14227.1 CDO77458.1 - 3.1e-09 36.4 0.1 6.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO77458.1 - 0.00015 21.4 0.0 0.00039 20.1 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO77458.1 - 0.037 13.5 0.0 0.08 12.4 0.0 1.6 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO77458.1 - 0.14 11.6 0.9 0.53 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) zf-CCHC_4 PF14392.1 CDO77458.1 - 0.21 11.2 2.5 0.44 10.2 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Uds1 PF15456.1 CDO77458.1 - 3.8 7.5 6.6 0.47 10.4 0.1 2.5 3 0 0 3 3 3 0 Up-regulated During Septation Transposase_21 PF02992.9 CDO77460.1 - 2.3e-18 66.1 0.0 4e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO77460.1 - 6.4e-08 32.0 0.1 2.6e-07 30.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) APG6 PF04111.7 CDO77461.1 - 0.0082 15.2 0.3 0.0082 15.2 0.2 2.4 2 1 1 3 3 3 2 Autophagy protein Apg6 YkyA PF10368.4 CDO77461.1 - 0.045 13.0 0.2 0.07 12.4 0.1 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Tropomyosin_1 PF12718.2 CDO77461.1 - 0.046 13.5 7.2 0.029 14.2 1.7 2.3 1 1 1 2 2 2 0 Tropomyosin like CENP-F_leu_zip PF10473.4 CDO77461.1 - 2.5 7.9 10.3 5.3 6.9 2.3 2.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABG_transport PF03806.8 CDO77465.1 - 0.055 11.4 0.0 0.063 11.2 0.0 1.0 1 0 0 1 1 1 0 AbgT putative transporter family Sad1_UNC PF07738.8 CDO77466.1 - 8e-10 38.6 0.0 4.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Nop14 PF04147.7 CDO77468.1 - 1.4 6.7 4.2 1.8 6.3 1.5 1.9 2 0 0 2 2 2 0 Nop14-like family RNase_H PF00075.19 CDO77469.1 - 1.3e-14 54.6 0.0 3.1e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 CDO77469.1 - 3.6e-13 49.3 0.0 9.1e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CDO77469.1 - 1.2e-07 31.3 0.2 2.7e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CDO77469.1 - 0.0024 18.1 0.2 0.018 15.3 0.0 2.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.18 CDO77469.1 - 9.7 6.3 12.5 6.3 6.9 1.8 3.6 3 0 0 3 3 3 0 Zinc knuckle MSP1_C PF07462.6 CDO77470.1 - 3.5 5.9 4.8 4.9 5.4 3.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF515 PF04415.7 CDO77470.1 - 3.9 5.5 6.1 5.1 5.2 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MFS_1 PF07690.11 CDO77471.1 - 1.1e-27 96.7 31.4 1.3e-14 53.6 11.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HSP70 PF00012.15 CDO77472.1 - 8.4e-78 261.7 8.1 8.4e-78 261.7 5.6 2.7 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CDO77472.1 - 0.014 13.9 1.4 0.055 12.0 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Trans_reg_C PF00486.23 CDO77472.1 - 0.05 13.5 0.2 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal MSA-2c PF12238.3 CDO77472.1 - 2.1 7.9 9.3 0.044 13.4 1.2 2.0 2 0 0 2 2 2 0 Merozoite surface antigen 2c Ish1 PF10281.4 CDO77473.1 - 6e-48 160.5 18.7 4.4e-07 29.8 1.1 7.6 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 CDO77473.1 - 7e-09 35.0 1.1 0.0027 17.2 0.0 5.8 7 0 0 7 7 7 2 HeH/LEM domain TryThrA_C PF12319.3 CDO77473.1 - 0.0012 18.0 13.6 0.0012 18.0 9.4 3.6 2 2 0 2 2 2 1 Tryptophan-Threonine-rich plasmodium antigen C terminal SAP PF02037.22 CDO77473.1 - 0.034 13.6 0.0 4.5 6.9 0.0 3.2 3 0 0 3 3 3 0 SAP domain SAM_2 PF07647.12 CDO77473.1 - 0.33 10.8 8.7 5.8 6.8 0.0 5.1 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) DUF3633 PF12315.3 CDO77473.1 - 3 7.1 5.6 6.4 6.0 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) UNC119_bdg PF15435.1 CDO77475.1 - 0.061 12.6 7.3 0.026 13.8 2.6 2.2 1 1 0 1 1 1 0 UNC119-binding protein C5orf30 homologue EcoRII-C PF09019.6 CDO77475.1 - 5.8 6.7 6.0 0.94 9.2 0.2 2.3 2 1 1 3 3 3 0 EcoRII C terminal SKG6 PF08693.5 CDO77476.1 - 0.011 14.9 0.3 0.026 13.8 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain WD40 PF00400.27 CDO77477.1 - 4.5e-11 42.1 0.3 0.00067 19.4 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat PTB PF08416.8 CDO77477.1 - 0.026 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine-binding domain SAC3_GANP PF03399.11 CDO77478.1 - 0.048 13.1 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2076 PF09849.4 CDO77478.1 - 0.092 12.7 0.9 0.16 11.9 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) HD PF01966.17 CDO77479.1 - 0.00016 21.7 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 HD domain Hormone_1 PF00103.15 CDO77479.1 - 0.023 14.0 0.0 0.08 12.2 0.0 1.7 2 0 0 2 2 2 0 Somatotropin hormone family EF1_GNE PF00736.14 CDO77480.1 - 1e-29 102.0 0.7 1.8e-29 101.2 0.5 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CDO77480.1 - 6e-14 51.8 4.9 6e-14 51.8 3.4 2.9 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 CDO77480.1 - 4.7e-06 27.0 0.0 1.1e-05 25.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDO77480.1 - 0.024 14.6 0.1 0.093 12.7 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO77480.1 - 0.031 14.1 0.1 1.3 8.9 0.1 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain dCMP_cyt_deam_1 PF00383.17 CDO77481.1 - 6.9e-08 32.0 0.1 8.3e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region BAG PF02179.11 CDO77483.1 - 1.5e-06 28.2 0.1 5.8e-06 26.3 0.1 2.0 1 0 0 1 1 1 1 BAG domain 2OG-FeII_Oxy_2 PF13532.1 CDO77484.1 - 5e-07 29.7 0.0 2.9e-06 27.2 0.0 1.8 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily SET PF00856.23 CDO77485.1 - 6.8e-14 52.4 0.0 8.2e-11 42.4 0.0 2.4 2 1 0 2 2 2 2 SET domain HTH_21 PF13276.1 CDO77485.1 - 0.0099 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 1 HTH-like domain SAF PF08666.7 CDO77485.1 - 0.12 12.7 0.0 22 5.5 0.0 2.4 2 0 0 2 2 2 0 SAF domain ABA_GPCR PF12430.3 CDO77486.1 - 1.7e-42 144.8 0.3 4.7e-42 143.3 0.2 1.8 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor MFS_1 PF07690.11 CDO77486.1 - 5.6e-29 100.9 75.2 3.2e-17 62.2 23.9 3.9 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF3735 PF12537.3 CDO77486.1 - 9.1e-13 48.0 0.1 5.3e-12 45.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) Cortex-I_coil PF09304.5 CDO77486.1 - 0.017 15.1 1.0 0.031 14.2 0.7 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil G-alpha PF00503.15 CDO77487.1 - 2e-101 339.5 0.0 3.1e-101 338.8 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CDO77487.1 - 5.7e-12 45.2 0.1 5.6e-08 32.2 0.0 2.6 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.1 CDO77487.1 - 0.0043 16.5 0.0 0.0085 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CDO77487.1 - 0.035 13.5 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 CDO77487.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PMEI PF04043.10 CDO77490.1 - 0.022 14.6 1.0 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Oxidored_FMN PF00724.15 CDO77491.1 - 4.5e-74 249.4 0.0 1.7e-51 175.2 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family GPI-anchored PF10342.4 CDO77492.1 - 1.2e-14 54.5 8.2 1.2e-14 54.5 5.7 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family fn3 PF00041.16 CDO77492.1 - 0.14 12.3 2.5 0.28 11.3 1.8 1.5 1 0 0 1 1 1 0 Fibronectin type III domain LRR_8 PF13855.1 CDO77493.1 - 0.24 11.1 2.4 31 4.4 0.0 3.6 4 0 0 4 4 4 0 Leucine rich repeat Oxidored_FMN PF00724.15 CDO77494.1 - 2.8e-81 273.1 0.0 3.3e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 CDO77495.1 - 1.3e-77 261.1 0.0 1.8e-59 201.4 0.0 2.9 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.19 CDO77496.1 - 4.7e-65 219.9 12.5 2.2e-64 217.7 5.3 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CDO77496.1 - 3.8e-15 55.4 23.0 3.2e-10 39.2 4.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CDO77496.1 - 3.2 7.8 7.1 0.51 10.4 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) GATA PF00320.22 CDO77497.1 - 6.4e-26 89.4 19.9 1.5e-15 56.2 2.4 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 CDO77497.1 - 1.6e-10 40.3 0.2 3.7e-10 39.1 0.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 CDO77497.1 - 0.18 11.1 6.7 0.15 11.3 0.5 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 CDO77497.1 - 0.71 9.8 5.7 7.4 6.6 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain RRN7 PF11781.3 CDO77497.1 - 0.87 9.1 10.3 0.056 12.9 0.4 2.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zinc_ribbon_5 PF13719.1 CDO77497.1 - 0.98 9.0 4.7 1.3 8.6 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.12 CDO77497.1 - 2.1 8.0 8.2 5.6 6.6 0.5 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zinc_ribbon_4 PF13717.1 CDO77497.1 - 2.4 7.9 6.0 1.1 8.9 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_3 PF14369.1 CDO77497.1 - 8.2 6.5 7.2 0.39 10.7 0.5 2.1 2 0 0 2 2 2 0 zinc-finger Cytochrom_c3_2 PF14537.1 CDO77497.1 - 9.2 6.6 12.1 72 3.8 1.3 2.6 1 1 1 2 2 2 0 Cytochrome c3 HypA PF01155.14 CDO77497.1 - 9.5 5.9 6.5 15 5.3 0.4 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Glyco_hydro_2_C PF02836.12 CDO77498.1 - 0.023 13.6 0.1 0.034 13.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF3034 PF11231.3 CDO77498.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3034) M157 PF11624.3 CDO77501.1 - 0.081 12.0 0.1 0.091 11.8 0.1 1.1 1 0 0 1 1 1 0 MHC class I-like protein M157 Pkinase PF00069.20 CDO77504.1 - 0.0015 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77504.1 - 0.037 13.1 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 CDO77506.1 - 0.081 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 CDO77507.1 - 0.18 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Trp_oprn_chp PF09534.5 CDO77508.1 - 7 6.2 8.4 0.59 9.7 1.5 2.1 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Acetyltransf_3 PF13302.1 CDO77509.1 - 1.5e-05 25.1 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDO77509.1 - 0.00024 21.0 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 CDO77509.1 - 0.0095 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EthD PF07110.6 CDO77511.1 - 2.6e-07 31.4 0.2 0.032 15.1 0.0 2.3 2 0 0 2 2 2 2 EthD domain ABM PF03992.11 CDO77511.1 - 0.0049 16.8 0.1 0.024 14.6 0.1 2.2 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase BDV_G PF06208.6 CDO77512.1 - 0.0027 16.7 0.5 0.0037 16.2 0.3 1.1 1 0 0 1 1 1 1 Borna disease virus G protein Cytochrom_C_asm PF01578.15 CDO77512.1 - 0.01 15.4 0.0 0.025 14.1 0.0 1.7 1 1 0 1 1 1 0 Cytochrome C assembly protein PP_M1 PF03012.9 CDO77512.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoprotein IncA PF04156.9 CDO77512.1 - 6.1 6.3 10.0 12 5.4 6.9 1.5 1 0 0 1 1 1 0 IncA protein Thaumatin PF00314.12 CDO77513.1 - 1.1e-61 207.9 4.7 1.4e-61 207.6 3.3 1.0 1 0 0 1 1 1 1 Thaumatin family DUF1275 PF06912.6 CDO77514.1 - 0.00059 19.0 2.8 0.00079 18.6 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2238 PF09997.4 CDO77514.1 - 0.041 13.2 0.9 0.079 12.3 0.7 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2238) Ceramidase PF05875.7 CDO77514.1 - 0.049 12.7 0.4 0.056 12.5 0.3 1.1 1 0 0 1 1 1 0 Ceramidase EI24 PF07264.6 CDO77514.1 - 0.26 10.7 5.2 0.36 10.2 3.6 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF1129 PF06570.6 CDO77514.1 - 0.62 9.3 2.3 0.73 9.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) CopD PF05425.8 CDO77514.1 - 0.99 9.6 8.7 1.3 9.2 6.1 1.1 1 0 0 1 1 1 0 Copper resistance protein D OPT PF03169.10 CDO77515.1 - 1.7e-173 578.4 41.5 2.2e-173 578.0 28.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_transf_8 PF01501.15 CDO77516.1 - 1.2e-18 67.4 0.0 1.7e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 CDO77516.1 - 6.3e-05 22.8 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF221 PF02714.10 CDO77517.1 - 2.7e-91 305.7 19.0 2.7e-91 305.7 13.2 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CDO77517.1 - 1.6e-39 134.9 1.8 1.6e-39 134.9 1.3 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CDO77517.1 - 5.7e-13 49.1 0.0 1.3e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) UPF0029 PF01205.14 CDO77518.1 - 3.8e-22 78.0 0.0 6.9e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF3445 PF11927.3 CDO77519.1 - 2.3e-57 194.2 0.0 2.9e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) CcoS PF03597.10 CDO77519.1 - 0.27 10.7 1.7 0.57 9.6 1.2 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type LisH PF08513.6 CDO77520.1 - 0.11 12.2 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 LisH HisG PF01634.13 CDO77521.1 - 2.1e-49 167.2 0.2 4.6e-49 166.1 0.1 1.6 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.6 CDO77521.1 - 1.2e-26 92.4 0.0 2.1e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain Calpain_III PF01067.17 CDO77521.1 - 7.6e-17 61.3 0.0 4.3e-09 36.1 0.0 3.6 3 1 0 3 3 3 2 Calpain large subunit, domain III Peptidase_C2 PF00648.16 CDO77521.1 - 8.1e-09 34.8 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 CDO77521.1 - 2.5e-06 27.2 3.2 4.8e-06 26.3 2.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain NMT1 PF09084.6 CDO77521.1 - 5.8e-05 22.7 0.1 9.6e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Methyltransf_20 PF12147.3 CDO77521.1 - 0.029 13.2 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Pkip-1 PF06878.6 CDO77521.1 - 0.091 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Pkip-1 protein Init_tRNA_PT PF04179.7 CDO77522.1 - 2.4e-106 356.3 0.0 3e-67 227.4 0.0 2.1 1 1 1 2 2 2 2 Initiator tRNA phosphoribosyl transferase DUF3602 PF12223.3 CDO77528.1 - 1.6e-15 57.2 21.4 2.8e-05 24.4 4.2 4.6 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) DUF605 PF04652.11 CDO77528.1 - 0.34 10.2 8.2 0.5 9.7 5.7 1.3 1 0 0 1 1 1 0 Vta1 like AA_permease_2 PF13520.1 CDO77529.1 - 5e-46 157.1 53.3 3.8e-35 121.2 20.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 CDO77529.1 - 7.3e-14 50.9 34.6 1.9e-10 39.7 12.9 2.6 1 1 1 2 2 2 2 Amino acid permease DUF1010 PF06231.6 CDO77529.1 - 0.27 11.2 7.8 0.22 11.5 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) Gln-synt_C PF00120.19 CDO77530.1 - 1.8e-54 184.6 0.0 2.3e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Pkinase PF00069.20 CDO77531.1 - 0.092 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Rubis-subs-bind PF09273.6 CDO77531.1 - 0.11 12.3 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding FHA PF00498.21 CDO77535.1 - 1.3e-16 60.4 0.1 4.5e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 FHA domain DUF1664 PF07889.7 CDO77535.1 - 0.0016 18.2 8.2 0.073 12.8 0.8 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) Lipoprotein_7 PF01540.11 CDO77535.1 - 0.018 14.0 1.2 0.021 13.8 0.0 1.6 2 0 0 2 2 2 0 Adhesin lipoprotein AAA_13 PF13166.1 CDO77535.1 - 0.12 10.7 6.1 0.24 9.8 1.7 2.1 2 0 0 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.7 CDO77535.1 - 0.62 9.7 29.4 0.8 9.4 2.4 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 CDO77535.1 - 1.6 7.8 4.8 7.5 5.6 1.3 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 CDO77535.1 - 1.9 8.7 11.3 50 4.2 0.2 4.3 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Kinesin-relat_1 PF12711.2 CDO77535.1 - 4.9 7.6 13.9 1.7 9.1 0.4 2.8 2 0 0 2 2 2 0 Kinesin motor Prefoldin_2 PF01920.15 CDO77535.1 - 5.4 6.8 19.2 1.1 9.0 2.8 3.9 3 1 0 3 3 3 0 Prefoldin subunit G-patch PF01585.18 CDO77537.1 - 1.7e-09 37.2 0.0 3.7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CDO77537.1 - 5.2e-08 32.6 0.1 5.2e-08 32.6 0.0 3.9 2 1 1 3 3 2 1 DExH-box splicing factor binding site AAA_11 PF13086.1 CDO77537.1 - 0.038 13.5 5.3 0.048 13.2 3.7 1.1 1 0 0 1 1 1 0 AAA domain Daxx PF03344.10 CDO77537.1 - 0.2 10.1 23.1 0.25 9.8 16.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 CDO77537.1 - 0.3 10.4 27.1 0.46 9.8 18.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIF_alpha PF05793.7 CDO77537.1 - 0.32 9.2 29.1 0.36 9.1 20.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAGA_bind PF06217.7 CDO77537.1 - 0.6 10.0 15.3 0.75 9.7 10.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Nop14 PF04147.7 CDO77537.1 - 0.63 7.9 23.0 0.68 7.7 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.6 CDO77537.1 - 0.74 9.4 33.5 1.1 8.8 23.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 MIP-T3 PF10243.4 CDO77537.1 - 0.75 8.1 32.2 0.88 7.9 22.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2413 PF10310.4 CDO77537.1 - 0.87 8.3 25.0 0.99 8.1 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CDC45 PF02724.9 CDO77537.1 - 0.95 7.4 19.9 1.1 7.1 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF966 PF06136.8 CDO77537.1 - 2 7.7 15.2 2.7 7.3 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAPS PF04499.10 CDO77537.1 - 2 6.9 15.0 2.2 6.7 10.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paramyxo_ncap PF00973.14 CDO77537.1 - 2.1 6.9 8.5 2.7 6.5 5.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RR_TM4-6 PF06459.7 CDO77537.1 - 3.2 7.5 21.6 4 7.2 15.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mitofilin PF09731.4 CDO77537.1 - 3.7 6.0 22.6 4.6 5.7 15.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein U79_P34 PF03064.11 CDO77537.1 - 5.5 6.4 23.0 7.5 5.9 15.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CRT10 PF08728.5 CDO77537.1 - 5.5 4.8 6.7 6.5 4.6 4.7 1.1 1 0 0 1 1 1 0 CRT10 ATP11 PF06644.6 CDO77537.1 - 7.4 5.9 14.3 9.5 5.6 9.9 1.3 1 0 0 1 1 1 0 ATP11 protein DUF4597 PF15366.1 CDO77538.1 - 0.0028 17.1 0.1 0.016 14.7 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4597) DUF4381 PF14316.1 CDO77538.1 - 0.02 14.9 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Ammonium_transp PF00909.16 CDO77542.1 - 1.9e-115 385.5 29.9 2.2e-115 385.3 20.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family FAD_binding_3 PF01494.14 CDO77544.1 - 2.2e-63 214.4 0.0 1.4e-60 205.2 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 CDO77544.1 - 1.9e-06 26.9 0.6 3.8e-06 26.0 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CDO77544.1 - 6.7e-05 22.8 0.0 0.00022 21.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO77544.1 - 0.00011 20.7 0.1 0.00019 20.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 CDO77544.1 - 0.00028 19.9 0.0 0.00046 19.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDO77544.1 - 0.00036 20.5 0.1 0.00093 19.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CDO77544.1 - 0.00039 19.6 0.0 0.0007 18.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 CDO77544.1 - 0.00062 18.7 0.2 0.00091 18.1 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 CDO77544.1 - 0.00063 18.9 0.2 0.001 18.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CDO77544.1 - 0.0012 17.5 0.0 0.0022 16.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 CDO77544.1 - 0.003 17.9 0.1 0.0084 16.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CDO77544.1 - 0.02 14.4 0.1 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 CDO77544.1 - 0.027 14.5 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CDO77544.1 - 0.031 13.2 0.3 0.066 12.1 0.2 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 CDO77545.1 - 3.7e-47 161.0 0.0 3.4e-31 108.5 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Neur PF00064.13 CDO77545.1 - 0.097 10.7 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Neuraminidase FAD_binding_3 PF01494.14 CDO77546.1 - 3.6e-71 240.0 0.0 4.8e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 CDO77546.1 - 7.4e-06 25.0 0.8 0.00015 20.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CDO77546.1 - 2.2e-05 24.7 0.4 0.17 12.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDO77546.1 - 0.0011 18.9 0.0 0.0024 17.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO77546.1 - 0.0017 16.9 0.4 0.0069 14.8 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 CDO77546.1 - 0.0024 16.5 0.0 0.0044 15.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.19 CDO77546.1 - 0.0033 16.3 0.1 0.17 10.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CDO77546.1 - 0.0073 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CDO77546.1 - 0.012 15.5 0.1 0.034 14.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CDO77546.1 - 0.014 14.4 0.4 0.05 12.6 0.3 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 CDO77546.1 - 0.086 11.6 0.2 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CDO77546.1 - 0.11 12.5 0.3 1.3 9.0 0.2 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2497 PF10691.4 CDO77546.1 - 0.16 11.9 0.1 0.35 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) E1_dh PF00676.15 CDO77547.1 - 6.2e-57 192.6 0.0 8.1e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component GPI-anchored PF10342.4 CDO77548.1 - 5.5e-09 36.3 0.0 9.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CCDC144C PF14915.1 CDO77549.1 - 0.047 12.6 0.1 0.074 11.9 0.1 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DivIC PF04977.10 CDO77549.1 - 0.051 13.0 0.6 0.12 11.9 0.2 1.7 2 0 0 2 2 2 0 Septum formation initiator EzrA PF06160.7 CDO77549.1 - 0.081 11.0 0.1 0.11 10.6 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Prefoldin_2 PF01920.15 CDO77549.1 - 0.088 12.5 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Prefoldin subunit bZIP_1 PF00170.16 CDO77549.1 - 0.1 12.6 1.7 0.13 12.2 0.4 1.7 2 0 0 2 2 2 0 bZIP transcription factor IncA PF04156.9 CDO77549.1 - 0.34 10.4 2.5 0.28 10.7 0.8 1.6 1 1 1 2 2 2 0 IncA protein HALZ PF02183.13 CDO77549.1 - 1.3 8.7 6.0 0.86 9.3 0.2 2.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper HR1 PF02185.11 CDO77550.1 - 0.0075 15.9 0.1 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Hr1 repeat Dynamitin PF04912.9 CDO77552.1 - 0.11 11.3 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Dynamitin RVT_1 PF00078.22 CDO77554.1 - 0.033 13.5 0.1 0.065 12.5 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 CDO77554.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Reverse transcriptase-like Beach PF02138.13 CDO77555.1 - 1.3e-64 218.2 0.0 5.6e-41 140.7 0.1 2.6 1 1 1 2 2 2 2 Beige/BEACH domain Laminin_G_3 PF13385.1 CDO77555.1 - 1.7e-11 44.6 0.0 3.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 CDO77555.1 - 1e-08 34.9 0.0 2.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH His_Phos_2 PF00328.17 CDO77556.1 - 9.5e-05 21.8 0.0 0.0001 21.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) F-box PF00646.28 CDO77558.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 F-box domain Methyltransf_11 PF08241.7 CDO77560.1 - 6.6e-18 64.9 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO77560.1 - 7.8e-12 45.7 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO77560.1 - 1e-11 44.6 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO77560.1 - 5.1e-11 42.8 0.0 9.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO77560.1 - 7e-09 36.0 0.0 1.3e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO77560.1 - 3.3e-08 33.4 0.0 5.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDO77560.1 - 2.4e-06 26.8 0.0 3.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CDO77560.1 - 0.0002 21.3 0.1 0.00058 19.8 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CDO77560.1 - 0.0046 16.6 0.0 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 CDO77560.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 CDO77560.1 - 0.051 12.6 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 CDO77560.1 - 0.09 12.1 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain F-box-like PF12937.2 CDO77562.1 - 0.00045 19.8 0.1 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like zf-RVT PF13966.1 CDO77562.1 - 0.00083 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_3 PF13358.1 CDO77564.1 - 1.2e-15 57.5 0.1 2.3e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease F-box-like PF12937.2 CDO77564.1 - 3.6e-06 26.5 0.1 8.7e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO77564.1 - 0.0005 19.6 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain Cast PF10174.4 CDO77565.1 - 1.5e-05 23.3 58.3 1.5e-05 23.3 40.4 2.2 2 0 0 2 2 2 2 RIM-binding protein of the cytomatrix active zone Reo_sigmaC PF04582.7 CDO77565.1 - 0.00021 20.5 17.3 0.03 13.5 4.3 4.0 1 1 0 3 3 3 2 Reovirus sigma C capsid protein ATG16 PF08614.6 CDO77565.1 - 0.00094 19.0 3.7 0.00094 19.0 2.6 6.2 2 1 4 6 6 6 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 CDO77565.1 - 0.0013 18.6 30.1 0.0013 18.6 20.8 5.9 2 2 4 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glyco_hydro_76 PF03663.9 CDO77566.1 - 9.1e-14 51.6 10.7 1.2e-13 51.2 7.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.9 CDO77567.1 - 4.8e-16 59.1 2.1 5.8e-16 58.8 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 CDO77567.1 - 0.064 12.2 0.2 0.12 11.4 0.0 1.4 1 1 0 1 1 1 0 Glycosyl Hydrolase Family 88 WD40 PF00400.27 CDO77568.1 - 1.3e-05 24.8 0.2 0.002 17.9 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat MoeA_C PF03454.10 CDO77569.1 - 0.02 14.8 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Exo70 PF03081.10 CDO77570.1 - 1.2e-42 146.0 0.0 2e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Snapin_Pallidin PF14712.1 CDO77570.1 - 0.047 13.9 1.1 0.12 12.6 0.8 1.7 1 0 0 1 1 1 0 Snapin/Pallidin CBFD_NFYB_HMF PF00808.18 CDO77570.1 - 0.056 13.5 0.0 0.64 10.1 0.0 2.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RNA_lig_T4_1 PF09511.5 CDO77571.1 - 2.7e-75 252.6 0.0 4.6e-75 251.8 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 CDO77571.1 - 7e-14 52.0 0.0 1.6e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 CDO77571.1 - 4.6e-10 39.1 0.0 8.3e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_17 PF13207.1 CDO77571.1 - 0.0047 17.7 0.0 0.018 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 CDO77571.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MFS_1 PF07690.11 CDO77572.1 - 7.7e-14 51.1 32.0 7.7e-14 51.1 22.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 CDO77572.1 - 3.9e-12 45.9 8.9 3.9e-12 45.9 6.1 3.1 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 Atg14 PF10186.4 CDO77573.1 - 3e-35 121.6 2.6 2.7e-20 72.5 0.0 2.0 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 4HBT_3 PF13622.1 CDO77573.1 - 0.0048 16.6 4.5 0.0084 15.8 3.1 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4140 PF13600.1 CDO77573.1 - 0.011 16.1 2.4 6.9 7.1 0.0 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CASP_C PF08172.7 CDO77573.1 - 0.026 13.5 0.2 0.049 12.6 0.1 1.4 1 0 0 1 1 1 0 CASP C terminal FlaC_arch PF05377.6 CDO77573.1 - 0.03 14.2 1.4 0.36 10.7 0.2 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cauli_AT PF03233.8 CDO77573.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Aphid transmission protein EzrA PF06160.7 CDO77573.1 - 0.058 11.5 1.5 0.068 11.3 0.4 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Phlebovirus_NSM PF07246.6 CDO77573.1 - 0.061 12.4 0.2 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Spc7 PF08317.6 CDO77573.1 - 0.11 11.0 2.1 0.86 8.1 0.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein FliD_N PF02465.13 CDO77573.1 - 0.14 12.5 0.7 5.4 7.4 0.1 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DivIVA PF05103.8 CDO77573.1 - 0.15 12.0 2.1 1.2 9.2 0.1 2.6 2 1 1 3 3 3 0 DivIVA protein bZIP_2 PF07716.10 CDO77573.1 - 0.28 11.0 3.9 4 7.3 1.5 2.7 2 1 0 2 2 2 0 Basic region leucine zipper Med9 PF07544.8 CDO77573.1 - 0.45 10.2 3.4 14 5.4 1.2 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-B_box PF00643.19 CDO77573.1 - 0.87 9.5 4.1 1.6 8.6 2.8 1.4 1 0 0 1 1 1 0 B-box zinc finger DUF605 PF04652.11 CDO77573.1 - 1.2 8.4 10.9 1.6 8.0 7.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF1192 PF06698.6 CDO77573.1 - 1.2 8.9 4.1 1.5 8.7 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) DivIC PF04977.10 CDO77573.1 - 1.4 8.4 5.2 10 5.7 0.4 2.7 3 0 0 3 3 3 0 Septum formation initiator GST_N_3 PF13417.1 CDO77574.1 - 5.8e-14 52.0 0.0 1.6e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO77574.1 - 7.7e-09 35.4 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO77574.1 - 2.1e-06 27.8 0.1 8.1e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO77574.1 - 0.011 15.6 1.4 0.019 14.8 0.2 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DDE_Tnp_4 PF13359.1 CDO77576.1 - 1.4e-15 57.1 0.0 2.2e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CDO77576.1 - 0.0036 16.6 0.1 0.0055 16.1 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO77576.1 - 0.017 15.3 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.16 CDO77576.1 - 0.054 13.0 0.3 0.23 10.9 0.2 1.9 1 1 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 CDO77577.1 - 0.0001 22.8 0.1 0.00017 22.1 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CDO77577.1 - 0.051 13.7 0.1 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Pap_E4 PF02711.9 CDO77577.1 - 2 9.2 5.2 4 8.3 0.8 2.7 2 1 0 2 2 2 0 E4 protein BTB PF00651.26 CDO77578.1 - 9.6e-05 22.3 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain LRR_8 PF13855.1 CDO77580.1 - 0.013 15.2 0.0 0.097 12.4 0.0 2.5 2 1 0 2 2 2 0 Leucine rich repeat F-box-like PF12937.2 CDO77581.1 - 0.00034 20.2 0.4 0.0012 18.5 0.0 2.1 2 1 0 2 2 2 1 F-box-like DUF3992 PF13157.1 CDO77586.1 - 0.021 15.0 1.5 0.021 15.0 1.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3992) Lipase_GDSL PF00657.17 CDO77590.1 - 4e-06 26.8 7.6 8.9e-06 25.6 5.3 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CDO77590.1 - 1.2e-05 25.4 2.6 1.6e-05 25.0 1.8 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family NIF PF03031.13 CDO77591.1 - 1.8e-38 131.7 0.0 2.9e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NAD_binding_5 PF07994.7 CDO77593.1 - 1.4e-107 359.5 0.0 1.7e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CDO77593.1 - 3.3e-44 149.2 0.0 5.4e-44 148.5 0.0 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase F-box-like PF12937.2 CDO77594.1 - 0.00083 19.0 0.0 0.0022 17.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO77594.1 - 0.013 15.1 0.0 0.039 13.6 0.0 1.8 1 0 0 1 1 1 0 F-box domain RhoGAP PF00620.22 CDO77595.1 - 1.1e-39 135.5 0.0 2.8e-39 134.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 CDO77595.1 - 1.2e-12 48.0 0.0 2.6e-09 37.0 0.0 2.9 3 0 0 3 3 3 2 RasGEF domain PH PF00169.24 CDO77595.1 - 2.1e-08 34.3 0.0 0.00035 20.7 0.0 2.5 2 0 0 2 2 2 2 PH domain RasGEF_N PF00618.15 CDO77595.1 - 7.6e-08 32.4 0.0 6.6e-07 29.3 0.0 2.6 1 1 0 1 1 1 1 RasGEF N-terminal motif PH_9 PF15410.1 CDO77595.1 - 1.7e-06 28.2 0.0 0.00013 22.1 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Nop14 PF04147.7 CDO77597.1 - 0.0033 15.4 2.7 0.004 15.1 1.9 1.1 1 0 0 1 1 1 1 Nop14-like family Spt5_N PF11942.3 CDO77597.1 - 0.011 16.3 10.1 0.011 16.3 7.0 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SDA1 PF05285.7 CDO77597.1 - 0.044 13.0 7.9 0.067 12.4 5.5 1.1 1 0 0 1 1 1 0 SDA1 Nucleoplasmin PF03066.10 CDO77597.1 - 0.18 11.2 7.2 0.078 12.4 1.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin AurF PF11583.3 CDO77597.1 - 0.22 10.4 0.7 0.42 9.4 0.3 1.5 2 0 0 2 2 2 0 P-aminobenzoate N-oxygenase AurF DUF2401 PF10287.4 CDO77599.1 - 3e-51 174.1 2.2 4.2e-51 173.7 1.5 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CDO77599.1 - 6.7e-19 67.8 0.0 1.5e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Lactamase_B_2 PF12706.2 CDO77600.1 - 1.7e-40 138.6 0.4 2.4e-40 138.1 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CDO77600.1 - 1.5e-14 54.0 0.0 5.1e-13 49.0 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CDO77600.1 - 4.2e-05 23.2 0.1 0.01 15.5 0.0 2.6 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily SGL PF08450.7 CDO77600.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Lactamase_B_2 PF12706.2 CDO77601.1 - 5.5e-40 136.9 0.0 9.8e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CDO77601.1 - 1.2e-14 54.3 0.0 2.3e-13 50.2 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CDO77601.1 - 0.011 15.4 0.0 0.45 10.1 0.0 2.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily DUF2419 PF10343.4 CDO77602.1 - 3.1e-83 279.3 0.0 4.2e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Cpn60_TCP1 PF00118.19 CDO77603.1 - 1.2e-89 301.1 0.1 3.2e-44 151.3 0.1 3.0 2 1 1 3 3 3 3 TCP-1/cpn60 chaperonin family DUF2910 PF11139.3 CDO77606.1 - 0.076 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) DUF2401 PF10287.4 CDO77608.1 - 2.2e-45 154.9 2.0 2.9e-45 154.5 1.4 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CDO77608.1 - 4.1e-21 74.8 0.1 9.7e-21 73.7 0.1 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) rve PF00665.21 CDO77609.1 - 1.7e-19 70.0 0.0 3.4e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CDO77609.1 - 4.7e-09 35.7 0.0 7.9e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain RVP PF00077.15 CDO77609.1 - 0.1 12.5 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease TORC_M PF12885.2 CDO77611.1 - 0.028 14.1 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Transposase_21 PF02992.9 CDO77612.1 - 2.8e-14 52.7 0.0 4e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 RVT_2 PF07727.9 CDO77614.1 - 5.4e-57 192.5 0.3 6e-57 192.4 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_2 PF14227.1 CDO77615.1 - 2.5e-12 46.4 0.0 3.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO77615.1 - 6.5e-07 29.1 0.0 7.8e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2 PF00096.21 CDO77616.1 - 0.9 10.0 3.4 0.37 11.2 0.5 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Retrotrans_gag PF03732.12 CDO77617.1 - 0.043 13.8 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Herpes_U44 PF04533.8 CDO77619.1 - 0.23 10.6 0.7 0.52 9.5 0.0 1.9 2 0 0 2 2 2 0 Herpes virus U44 protein Mito_carr PF00153.22 CDO77620.1 - 1.9e-45 152.5 2.1 6.8e-18 64.1 0.0 3.9 3 2 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2b PF00587.20 CDO77621.1 - 9.5e-47 158.7 0.1 1.5e-46 158.1 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CDO77621.1 - 1.1e-20 73.3 0.0 2.5e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain APH PF01636.18 CDO77622.1 - 0.0009 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1682 PF07946.9 CDO77624.1 - 0.42 9.4 0.0 0.42 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Dapper PF15268.1 CDO77624.1 - 5.1 5.7 16.0 7.5 5.2 11.1 1.3 1 0 0 1 1 1 0 Dapper CbiM PF01891.11 CDO77625.1 - 0.24 10.9 10.1 0.51 9.9 7.0 1.5 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Bestrophin PF01062.16 CDO77625.1 - 0.7 8.7 6.3 0.11 11.4 1.5 1.6 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Methyltransf_2 PF00891.13 CDO77626.1 - 3.3e-16 59.2 0.0 8.1e-16 57.9 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_18 PF12847.2 CDO77626.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain ubiquitin PF00240.18 CDO77627.1 - 2.3e-69 228.7 9.0 1.6e-34 117.0 0.5 2.8 2 1 1 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.3 CDO77627.1 - 5.6e-37 125.2 7.9 1.7e-19 69.2 0.5 2.9 2 1 1 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CDO77627.1 - 2.7e-13 49.9 1.8 3.5e-05 23.9 0.1 3.3 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CDO77627.1 - 9.1e-09 35.2 0.3 0.00033 20.4 0.0 2.1 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CDO77627.1 - 3.9e-07 29.9 0.2 0.038 13.8 0.0 2.7 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CDO77627.1 - 1.2e-06 28.6 0.1 0.047 13.8 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CDO77627.1 - 6.5e-05 22.9 0.1 0.49 10.4 0.0 2.7 4 0 0 4 4 2 2 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 CDO77627.1 - 0.0007 19.2 1.2 0.91 9.3 0.1 2.3 2 0 0 2 2 2 2 FlgD Ig-like domain TUG-UBL1 PF11470.3 CDO77627.1 - 0.0021 17.9 0.3 2.2 8.2 0.0 2.3 2 0 0 2 2 2 2 GLUT4 regulating protein TUG DUF3221 PF11518.3 CDO77627.1 - 0.014 15.0 0.1 5.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) Plexin_cytopl PF08337.7 CDO77627.1 - 0.034 12.4 4.2 10 4.2 0.2 3.7 2 1 2 4 4 4 0 Plexin cytoplasmic RasGAP domain USP7_C2 PF14533.1 CDO77627.1 - 0.061 12.7 0.2 7.7 5.8 0.0 2.1 1 1 0 2 2 2 0 Ubiquitin-specific protease C-terminal Tash_PEST PF07708.6 CDO77627.1 - 0.081 12.8 10.5 1.7 8.6 1.2 2.4 2 0 0 2 2 2 0 Tash protein PEST motif DUF3861 PF12977.2 CDO77627.1 - 0.088 12.9 0.6 13 5.9 0.0 2.4 1 1 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) DUF493 PF04359.9 CDO77627.1 - 0.11 12.8 0.1 3.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF493) ACT_4 PF13291.1 CDO77627.1 - 0.11 12.8 0.0 19 5.6 0.0 2.3 2 0 0 2 2 2 0 ACT domain DUF2207 PF09972.4 CDO77627.1 - 0.13 10.8 2.9 3.3 6.1 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) GABP-alpha PF11620.3 CDO77627.1 - 0.15 12.0 0.8 15 5.6 0.1 2.2 2 0 0 2 2 2 0 GA-binding protein alpha chain DUF3415 PF11895.3 CDO77628.1 - 2.9e-29 100.7 1.3 5.9e-29 99.7 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 CDO77628.1 - 3.1e-21 75.9 0.0 4.8e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase p450 PF00067.17 CDO77629.1 - 7.3e-61 206.1 0.0 3.2e-59 200.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 EB PF01683.13 CDO77631.1 - 1.1 9.4 31.9 0.26 11.4 2.6 4.3 3 3 0 3 3 3 0 EB module ETF_QO PF05187.8 CDO77632.1 - 1.3e-09 38.0 0.0 2.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CDO77632.1 - 2.3e-08 33.3 0.4 2e-05 23.6 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDO77632.1 - 1.3e-07 31.5 0.0 4.8e-07 29.7 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CDO77632.1 - 2.5e-06 26.6 0.8 5.4e-05 22.2 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 CDO77632.1 - 5e-06 26.7 0.0 8.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDO77632.1 - 3.8e-05 23.6 0.0 6.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDO77632.1 - 3.9e-05 22.8 0.0 0.00037 19.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 CDO77632.1 - 6.8e-05 22.6 0.4 0.00021 21.0 0.3 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 CDO77632.1 - 0.0001 20.9 0.4 0.00015 20.3 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 CDO77632.1 - 0.00021 20.4 0.1 0.00032 19.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 CDO77632.1 - 0.0012 17.8 0.2 0.0019 17.2 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 CDO77632.1 - 0.0052 15.9 0.2 0.0087 15.1 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 CDO77632.1 - 0.079 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 CDO77632.1 - 0.1 11.2 0.0 0.25 9.9 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 CDO77632.1 - 0.12 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.13 CDO77633.1 - 1.7e-32 112.3 0.0 2.9e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sec7 PF01369.15 CDO77634.1 - 2.2e-22 79.6 0.0 3.5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain FixG_C PF11614.3 CDO77634.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase CHCH PF06747.8 CDO77635.1 - 4.2e-06 26.5 5.1 7.6e-06 25.7 3.5 1.4 1 0 0 1 1 1 1 CHCH domain Kei1 PF08552.6 CDO77636.1 - 0.12 12.0 1.6 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Herpes_capsid PF06112.6 CDO77636.1 - 0.3 11.0 5.6 0.61 10.1 3.9 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Sporozoite_P67 PF05642.6 CDO77636.1 - 2.2 6.0 7.1 2.6 5.7 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.6 CDO77636.1 - 5.3 4.8 12.8 7.8 4.3 8.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DIM PF08194.7 CDO77637.1 - 1.9 8.4 4.6 2.3 8.2 0.4 2.7 2 0 0 2 2 2 0 DIM protein MCLC PF05934.6 CDO77637.1 - 2.1 6.5 8.3 3.2 5.9 5.8 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) E1-E2_ATPase PF00122.15 CDO77638.1 - 4.1e-31 107.7 0.0 9.2e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CDO77638.1 - 8.4e-25 88.0 0.0 1.7e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDO77638.1 - 4.5e-23 82.7 0.0 4.4e-22 79.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 CDO77638.1 - 5.6e-20 71.3 0.0 1.7e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_C PF00689.16 CDO77638.1 - 3.5e-07 29.9 6.0 3.5e-07 29.9 4.2 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 CDO77638.1 - 2.9e-05 23.9 0.0 6.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CDO77638.1 - 5.8e-05 22.4 0.0 0.00013 21.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CDO77638.1 - 0.18 11.3 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ssl1 PF04056.9 CDO77639.1 - 8.3e-71 237.5 0.0 1.1e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 CDO77639.1 - 1.9e-11 44.3 0.0 3.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain ADH_N PF08240.7 CDO77640.1 - 1.8e-27 95.2 1.7 2.9e-27 94.5 1.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CDO77640.1 - 3.3e-19 68.7 0.0 5.2e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CDO77640.1 - 0.00022 20.4 0.0 0.00038 19.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 CDO77640.1 - 0.00037 21.3 0.0 0.00059 20.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CDO77640.1 - 0.0084 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 CDO77640.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ApbA PF02558.11 CDO77640.1 - 0.036 13.5 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 CDO77640.1 - 0.048 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Phage_integrase PF00589.17 CDO77642.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family DDE_3 PF13358.1 CDO77644.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO77644.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Trp_syntA PF00290.15 CDO77645.1 - 3.6e-86 287.8 0.2 4.9e-86 287.4 0.1 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 CDO77645.1 - 9e-45 153.2 0.4 1.4e-44 152.6 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 CDO77645.1 - 0.00014 21.2 0.0 0.00061 19.1 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 CDO77645.1 - 0.018 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase PA PF02225.17 CDO77645.1 - 0.087 12.5 0.6 3.3 7.4 0.0 2.7 2 0 0 2 2 2 0 PA domain PcrB PF01884.12 CDO77645.1 - 0.13 11.5 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 PcrB family Asparaginase PF00710.15 CDO77646.1 - 7.7e-105 350.2 0.0 9e-68 228.4 0.0 2.1 1 1 1 2 2 2 2 Asparaginase Ank_2 PF12796.2 CDO77646.1 - 3e-08 33.8 0.0 6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDO77646.1 - 5.1e-07 29.1 0.2 3.1e-05 23.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CDO77646.1 - 5.4e-05 23.0 0.0 0.00034 20.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CDO77646.1 - 0.00014 22.0 0.2 0.00035 20.7 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDO77646.1 - 0.039 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) GATase_7 PF13537.1 CDO77646.1 - 0.14 11.9 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain NYD-SP28 PF14772.1 CDO77647.1 - 0.035 14.1 18.2 0.11 12.5 7.9 3.2 2 1 0 2 2 2 0 Sperm tail DUF1515 PF07439.6 CDO77647.1 - 0.23 11.3 2.6 0.68 9.7 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF342 PF03961.8 CDO77647.1 - 0.27 9.5 15.8 0.061 11.7 6.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) AAA_13 PF13166.1 CDO77647.1 - 0.3 9.4 16.5 0.45 8.9 11.4 1.1 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 CDO77647.1 - 0.6 10.2 14.1 0.19 11.8 6.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 CDO77647.1 - 2.4 7.0 23.1 0.48 9.3 5.6 2.8 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Bap31 PF05529.7 CDO77647.1 - 3.2 7.1 19.3 1.5 8.2 3.2 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like vMSA PF00695.14 CDO77647.1 - 3.9 6.5 7.8 0.72 8.9 2.3 2.0 2 1 0 2 2 2 0 Major surface antigen from hepadnavirus A_deaminase PF00962.17 CDO77648.1 - 5e-44 150.5 0.0 1.1e-43 149.4 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase Myb_DNA-bind_4 PF13837.1 CDO77649.1 - 1.1e-09 38.2 0.1 2.2e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO77649.1 - 1.1e-06 29.1 0.1 1.8e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO77649.1 - 7.8e-05 22.5 0.1 0.00024 20.9 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain LAT PF15234.1 CDO77649.1 - 0.024 14.0 1.1 0.044 13.2 0.8 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Myb_DNA-bind_6 PF13921.1 CDO77649.1 - 0.031 14.3 0.1 0.079 13.0 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CDO77649.1 - 0.082 12.9 1.5 0.18 11.8 0.5 2.1 2 1 0 2 2 2 0 Myb-like DNA-binding domain Myc_N PF01056.13 CDO77649.1 - 0.14 11.3 4.7 0.028 13.5 0.9 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Sigma70_ner PF04546.8 CDO77649.1 - 0.17 11.5 6.1 0.091 12.3 2.7 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 CDO77649.1 - 6.6 7.0 10.3 14 5.9 7.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DDE_Tnp_4 PF13359.1 CDO77650.1 - 4.4e-19 68.6 0.0 6.4e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 CDO77650.1 - 0.0029 17.1 0.0 0.0061 16.1 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain PYC_OADA PF02436.13 CDO77651.1 - 2.7e-70 235.7 0.0 4e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.14 CDO77651.1 - 4.4e-20 72.3 0.5 7.8e-20 71.5 0.3 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 CDO77651.1 - 1.5e-17 62.9 4.9 4.7e-17 61.3 3.4 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CDO77651.1 - 6.2e-12 44.9 4.9 4.2e-06 26.3 0.0 2.9 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD PF00529.15 CDO77651.1 - 1.4e-07 31.1 4.7 0.00042 19.7 0.2 2.9 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_3 PF13437.1 CDO77651.1 - 2.4e-06 27.8 0.7 0.094 13.0 0.1 2.8 2 0 0 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 CDO77651.1 - 0.00076 19.1 1.9 0.0021 17.7 0.5 2.2 1 1 1 2 2 2 1 Glycine cleavage H-protein HlyD_2 PF12700.2 CDO77651.1 - 0.0016 17.6 0.8 0.63 9.1 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein NQRA PF05896.6 CDO77651.1 - 0.0045 16.2 0.3 0.012 14.8 0.2 1.7 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.1 CDO77651.1 - 0.023 14.3 2.2 0.11 12.2 1.4 2.2 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 CDO77651.1 - 0.042 13.5 0.5 0.3 10.7 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) PTS_EIIA_1 PF00358.15 CDO77651.1 - 0.074 12.6 0.8 0.25 10.8 0.3 2.2 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 CPSase_L_D2 PF02786.12 CDO77652.1 - 1.1e-79 266.6 0.1 1.7e-79 266.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CDO77652.1 - 2.1e-37 127.5 0.0 5e-37 126.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CDO77652.1 - 1.4e-30 105.4 0.0 2.9e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATPgrasp_Ter PF15632.1 CDO77652.1 - 5.2e-19 68.1 0.0 4.2e-18 65.1 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CDO77652.1 - 8.4e-18 64.7 0.1 1.6e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CDO77652.1 - 2.2e-11 43.5 0.0 5.1e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CDO77652.1 - 2.1e-07 30.4 0.0 4.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CDO77652.1 - 6.2e-05 22.5 0.0 0.00021 20.8 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CDO77652.1 - 8.6e-05 22.4 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CDO77652.1 - 0.003 17.1 0.0 0.0072 15.9 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain UAA PF08449.6 CDO77653.1 - 8.2e-17 61.0 14.8 1e-16 60.7 10.3 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CDO77653.1 - 1.1e-10 41.3 3.6 1.1e-10 41.3 2.5 3.3 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 CDO77653.1 - 0.004 17.1 21.2 0.0057 16.7 4.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family FA_hydroxylase PF04116.8 CDO77654.1 - 2.8e-18 66.3 11.8 2.8e-18 66.3 8.2 2.7 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Ribosomal_L28e PF01778.12 CDO77655.1 - 4.9e-24 84.9 1.3 1.3e-23 83.5 0.9 1.8 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 CDO77655.1 - 5.8e-18 64.8 39.8 3.1e-17 62.5 18.7 3.4 2 1 0 2 2 2 1 Mak16 protein C-terminal region TFIIA PF03153.8 CDO77655.1 - 0.041 13.7 8.4 0.053 13.4 5.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIF_alpha PF05793.7 CDO77655.1 - 0.084 11.2 25.0 0.12 10.7 17.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 CDO77655.1 - 4.1 5.7 22.0 4.9 5.5 15.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF1640 PF07798.6 CDO77656.1 - 3e-64 216.3 12.5 3.4e-64 216.1 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF2077 PF09850.4 CDO77656.1 - 0.12 11.7 2.8 1.1 8.6 0.0 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) KIAA1430 PF13879.1 CDO77656.1 - 2.3 8.7 10.6 3.8 8.0 7.1 1.5 1 1 0 1 1 1 0 KIAA1430 homologue DivIC PF04977.10 CDO77656.1 - 5.3 6.5 11.5 0.96 8.9 3.6 2.4 1 1 1 2 2 2 0 Septum formation initiator Guanylate_kin PF00625.16 CDO77657.1 - 6.1e-70 234.3 0.0 8.2e-70 233.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 CDO77657.1 - 1.2e-08 35.1 0.0 4.5e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 CDO77657.1 - 5.5e-07 29.5 0.0 1.4e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CDO77657.1 - 4.6e-06 26.8 0.0 0.0001 22.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CDO77657.1 - 3.4e-05 24.6 0.1 0.00011 23.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDO77657.1 - 5.8e-05 23.3 0.0 0.0003 21.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CDO77657.1 - 0.00024 20.3 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 CDO77657.1 - 0.00083 19.2 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CDO77657.1 - 0.001 19.3 0.0 0.0015 18.8 0.0 1.4 1 1 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 CDO77657.1 - 0.0019 17.9 0.1 0.0092 15.7 0.1 1.9 1 1 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 CDO77657.1 - 0.002 17.1 0.0 0.01 14.8 0.0 1.8 1 1 0 1 1 1 1 KAP family P-loop domain MMR_HSR1 PF01926.18 CDO77657.1 - 0.0031 17.4 0.0 0.0053 16.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CDO77657.1 - 0.0034 17.8 0.0 0.0062 17.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_10 PF12846.2 CDO77657.1 - 0.0041 16.6 0.0 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 CDO77657.1 - 0.0048 16.5 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 CDO77657.1 - 0.0063 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 CDO77657.1 - 0.0073 16.0 0.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CDO77657.1 - 0.008 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 CDO77657.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CDO77657.1 - 0.018 14.7 0.0 0.025 14.2 0.0 1.5 1 1 0 1 1 1 0 NTPase PTS_IIB PF02302.12 CDO77657.1 - 0.019 15.4 0.0 8.6 6.9 0.0 3.0 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit AAA PF00004.24 CDO77657.1 - 0.026 14.7 0.1 0.092 12.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CDO77657.1 - 0.042 12.5 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2075 PF09848.4 CDO77657.1 - 0.046 12.7 0.0 0.7 8.7 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 CDO77657.1 - 0.066 12.9 0.1 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 CDO77657.1 - 0.1 12.1 0.1 0.21 11.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CDO77657.1 - 0.15 11.4 0.0 0.63 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 CDO77658.1 - 6.2e-64 215.6 0.0 8e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77658.1 - 1.6e-35 122.4 0.0 2.2e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO77658.1 - 6.4e-08 31.8 0.0 1.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDO77658.1 - 0.00048 19.2 0.8 0.003 16.6 0.0 2.5 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDO77658.1 - 0.0041 16.8 0.4 0.009 15.7 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CDO77658.1 - 0.033 13.5 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family UAA PF08449.6 CDO77659.1 - 1.5e-64 217.7 4.9 1.8e-64 217.5 3.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CDO77659.1 - 1.4e-06 28.3 20.8 0.00015 21.8 4.5 2.9 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 CDO77659.1 - 0.00028 20.5 11.0 0.00063 19.4 1.2 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CDO77659.1 - 0.0054 16.9 2.4 0.0054 16.9 1.6 2.5 3 0 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CDO77659.1 - 0.03 13.4 0.4 0.052 12.6 0.3 1.3 1 0 0 1 1 1 0 Nucleotide-sugar transporter DUF914 PF06027.7 CDO77659.1 - 0.034 13.0 1.0 0.085 11.6 0.3 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) DUF1686 PF07937.6 CDO77659.1 - 0.055 13.1 0.8 0.086 12.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) ABC_membrane PF00664.18 CDO77661.1 - 1e-62 212.0 35.1 1.9e-36 125.9 3.9 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 CDO77661.1 - 5.7e-53 178.8 0.0 3.4e-32 111.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CDO77661.1 - 2.8e-10 39.8 0.0 0.0072 15.5 0.0 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDO77661.1 - 1e-06 28.9 2.5 0.01 15.8 0.2 4.3 2 2 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CDO77661.1 - 1.6e-06 28.2 0.2 0.0032 17.4 0.1 2.9 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 CDO77661.1 - 1.7e-05 24.7 0.1 0.17 11.8 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 CDO77661.1 - 0.00011 21.6 0.0 0.11 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CDO77661.1 - 0.00024 20.5 0.8 0.13 11.7 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 CDO77661.1 - 0.00049 20.5 4.0 0.46 11.0 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 CDO77661.1 - 0.0013 18.3 0.1 0.53 9.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CDO77661.1 - 0.0035 17.7 0.0 4.5 7.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 CDO77661.1 - 0.0043 15.8 0.0 1.7 7.3 0.0 2.3 2 0 0 2 2 2 2 ArgK protein DUF87 PF01935.12 CDO77661.1 - 0.0054 16.5 6.3 0.056 13.2 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function DUF87 DUF258 PF03193.11 CDO77661.1 - 0.013 14.7 0.4 2.9 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CDO77661.1 - 0.028 14.2 3.1 0.84 9.4 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.1 CDO77661.1 - 0.04 14.0 1.5 3.3 7.8 0.1 3.7 3 1 0 3 3 3 0 AAA domain MobB PF03205.9 CDO77661.1 - 0.04 13.6 1.4 2.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CDO77661.1 - 0.044 13.4 0.3 3.7 7.1 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase T2SE PF00437.15 CDO77661.1 - 0.044 12.6 0.0 3.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Bac_DnaA PF00308.13 CDO77661.1 - 0.053 13.1 0.7 9.3 5.8 0.0 2.8 3 0 0 3 3 3 0 Bacterial dnaA protein ABC_ATPase PF09818.4 CDO77661.1 - 0.066 11.7 0.0 0.066 11.7 0.0 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.7 CDO77661.1 - 0.076 12.6 0.6 12 5.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 CDO77661.1 - 0.089 12.5 0.7 0.79 9.5 0.2 2.8 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 CDO77661.1 - 0.093 11.8 0.4 4.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.2 CDO77661.1 - 0.11 11.8 4.0 6.6 6.0 0.1 2.8 2 1 0 2 2 2 0 AAA-like domain cobW PF02492.14 CDO77661.1 - 0.11 11.9 3.1 1.4 8.3 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 CDO77661.1 - 0.15 10.8 1.0 16 4.2 0.3 2.7 2 1 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 CDO77661.1 - 0.19 11.3 0.5 0.52 9.9 0.1 1.8 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 Pox_A32 PF04665.7 CDO77661.1 - 0.28 10.4 0.7 0.73 9.0 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein MS_channel PF00924.13 CDO77662.1 - 3.2e-18 65.8 1.1 5.2e-18 65.1 0.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CDO77662.1 - 0.00011 21.2 0.1 0.00027 20.0 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CDO77662.1 - 0.00095 18.8 0.1 0.0024 17.6 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CDO77662.1 - 0.0017 17.6 0.2 0.0045 16.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CDO77662.1 - 0.048 13.8 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_C12 PF01088.16 CDO77663.1 - 3.9e-29 101.3 0.0 3.7e-22 78.5 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3678 PF12435.3 CDO77663.1 - 0.019 14.5 0.3 0.033 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) LAB_N PF07578.6 CDO77663.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain zf-ZPR1 PF03367.8 CDO77664.1 - 1.8e-108 358.8 0.3 1.8e-55 186.4 0.0 3.2 2 1 1 3 3 3 3 ZPR1 zinc-finger domain UPF0547 PF10571.4 CDO77664.1 - 0.14 11.8 3.5 7 6.4 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.1 CDO77664.1 - 0.19 10.9 4.8 2.7 7.2 1.1 2.8 2 1 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 CDO77664.1 - 0.85 9.3 5.3 1.5 8.5 0.3 2.6 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 CDO77664.1 - 4.1 7.0 9.9 9.5 5.8 0.2 3.7 3 0 0 3 3 3 0 zinc-ribbon domain Nup35_RRM PF05172.8 CDO77665.1 - 0.0012 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Cyto_heme_lyase PF01265.12 CDO77667.1 - 6.5e-73 245.5 0.0 7.5e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase IL11 PF07400.6 CDO77667.1 - 0.07 12.6 0.6 0.55 9.7 0.0 2.1 2 0 0 2 2 2 0 Interleukin 11 Tim44 PF04280.10 CDO77668.1 - 9.2e-33 113.3 1.6 1.2e-32 112.8 0.1 1.9 2 0 0 2 2 2 1 Tim44-like domain DMPK_coil PF08826.5 CDO77668.1 - 0.022 14.6 0.5 0.022 14.6 0.4 2.4 3 0 0 3 3 3 0 DMPK coiled coil domain like IMS PF00817.15 CDO77668.1 - 0.065 13.0 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 impB/mucB/samB family ADH_zinc_N PF00107.21 CDO77669.1 - 6.3e-12 45.1 0.0 1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO77669.1 - 8.6e-05 22.2 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 CDO77669.1 - 0.0098 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CDO77669.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding EMP24_GP25L PF01105.19 CDO77670.1 - 1e-48 165.4 0.0 1.2e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Brix PF04427.13 CDO77671.1 - 1.9e-34 118.9 0.1 2.9e-34 118.3 0.1 1.2 1 0 0 1 1 1 1 Brix domain Virul_Fac PF10139.4 CDO77671.1 - 0.27 9.1 9.3 0.0062 14.5 1.3 1.8 2 0 0 2 2 2 0 Putative bacterial virulence factor NCD2 PF04905.8 CDO77671.1 - 0.46 10.2 7.8 4.7 6.9 1.1 2.4 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) Glyco_hydro_7 PF00840.15 CDO77672.1 - 4.8e-212 703.9 17.2 5.6e-212 703.7 11.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pkinase PF00069.20 CDO77673.1 - 0.00013 21.1 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.15 CDO77673.1 - 0.0014 17.8 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 CDO77673.1 - 0.0028 16.3 0.0 0.023 13.3 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1679) APH PF01636.18 CDO77675.1 - 9.8e-11 41.8 1.8 2.3e-10 40.6 1.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CDO77675.1 - 0.004 16.3 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Reo_sigmaC PF04582.7 CDO77676.1 - 0.0035 16.5 3.1 0.19 10.8 1.9 2.1 2 0 0 2 2 2 1 Reovirus sigma C capsid protein IncA PF04156.9 CDO77676.1 - 0.005 16.4 10.1 0.3 10.6 4.4 2.3 2 0 0 2 2 2 2 IncA protein CCDC144C PF14915.1 CDO77676.1 - 0.0051 15.7 3.4 0.0051 15.7 2.3 2.4 3 0 0 3 3 3 1 CCDC144C protein coiled-coil region Spc7 PF08317.6 CDO77676.1 - 0.016 13.8 4.4 0.52 8.9 0.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Filament PF00038.16 CDO77676.1 - 0.028 13.8 3.6 0.13 11.7 0.3 2.1 2 0 0 2 2 2 0 Intermediate filament protein MscS_porin PF12795.2 CDO77676.1 - 0.031 13.5 13.3 0.048 12.9 4.4 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.4 CDO77676.1 - 0.056 13.3 14.5 0.15 11.9 5.9 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 CDO77676.1 - 0.095 13.0 3.4 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CALCOCO1 PF07888.6 CDO77676.1 - 0.097 10.9 7.3 0.18 10.0 2.3 2.0 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cep57_CLD_2 PF14197.1 CDO77676.1 - 0.12 12.3 14.1 0.97 9.4 0.9 3.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 FH2 PF02181.18 CDO77676.1 - 0.14 10.9 3.7 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain Mnd1 PF03962.10 CDO77676.1 - 0.14 11.7 6.0 1.2 8.7 1.2 2.2 2 0 0 2 2 2 0 Mnd1 family GAS PF13851.1 CDO77676.1 - 0.17 11.0 6.9 0.71 9.0 1.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 CDO77676.1 - 0.17 10.3 14.0 0.14 10.6 0.2 2.1 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF4140 PF13600.1 CDO77676.1 - 0.18 12.2 7.0 0.81 10.1 1.2 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tropomyosin PF00261.15 CDO77676.1 - 0.25 10.3 10.2 0.25 10.4 3.1 2.2 2 0 0 2 2 2 0 Tropomyosin Macoilin PF09726.4 CDO77676.1 - 0.26 9.5 3.9 0.049 11.9 0.3 1.5 2 0 0 2 2 2 0 Transmembrane protein NPV_P10 PF05531.7 CDO77676.1 - 0.4 10.9 6.2 0.88 9.8 0.3 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Uds1 PF15456.1 CDO77676.1 - 1.4 8.8 9.4 4 7.4 0.1 2.5 2 0 0 2 2 2 0 Up-regulated During Septation Seryl_tRNA_N PF02403.17 CDO77676.1 - 1.6 8.7 5.9 11 6.0 0.8 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 CDO77676.1 - 1.7 7.6 8.3 0.26 10.3 2.3 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 TBPIP PF07106.8 CDO77676.1 - 1.8 8.0 5.5 14 5.2 0.1 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 CDO77676.1 - 2.1 8.1 3.9 17 5.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lipoprotein_20 PF13942.1 CDO77676.1 - 2.6 7.5 8.3 6.4 6.2 0.1 2.3 2 0 0 2 2 2 0 YfhG lipoprotein DMPK_coil PF08826.5 CDO77676.1 - 2.9 7.8 10.2 0.34 10.8 2.8 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Myosin_tail_1 PF01576.14 CDO77676.1 - 3 5.4 12.8 1.9 6.0 3.5 2.1 2 0 0 2 2 2 0 Myosin tail Tropomyosin_1 PF12718.2 CDO77676.1 - 4 7.2 11.9 8.5 6.2 0.3 2.3 2 0 0 2 2 2 0 Tropomyosin like DUF4164 PF13747.1 CDO77676.1 - 5.5 7.1 12.9 0.59 10.3 2.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) SYCE1 PF15233.1 CDO77676.1 - 5.5 6.9 9.5 10 6.0 1.8 2.2 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF2968 PF11180.3 CDO77676.1 - 5.7 6.2 10.5 7.3 5.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) ADIP PF11559.3 CDO77676.1 - 9.1 6.1 10.1 21 5.0 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1771 PF08590.5 CDO77677.1 - 4e-13 49.1 8.2 7.4e-13 48.3 5.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 CDO77677.1 - 1.8e-09 37.0 7.8 4.7e-06 26.1 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 CDO77677.1 - 1e-05 25.6 0.1 3.6e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Smr domain UBA PF00627.26 CDO77677.1 - 0.0085 15.9 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HBS1_N PF08938.5 CDO77677.1 - 0.033 14.3 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus zf-C3H1 PF10650.4 CDO77677.1 - 0.13 11.7 1.8 10 5.6 0.1 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain DUF1570 PF07607.6 CDO77678.1 - 0.25 11.3 3.1 0.86 9.6 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1570) Fic PF02661.13 CDO77679.1 - 1.4e-05 25.6 0.1 4.4e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 Fic/DOC family SPDY PF03771.11 CDO77679.1 - 0.014 14.8 0.2 0.038 13.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF317) PAS_8 PF13188.1 CDO77680.1 - 0.096 12.5 0.0 0.31 10.9 0.0 1.8 1 1 1 2 2 2 0 PAS domain Coprogen_oxidas PF01218.13 CDO77681.1 - 1.5e-106 355.2 0.0 2.9e-106 354.3 0.0 1.5 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Lactamase_B PF00753.22 CDO77683.1 - 9.2e-08 31.9 5.8 1.8e-07 31.0 4.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CDO77683.1 - 0.0026 17.3 0.9 0.0086 15.6 0.5 2.1 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Tcp11 PF05794.8 CDO77684.1 - 8.5e-12 44.5 0.0 1.5e-08 33.8 0.0 2.6 2 1 0 2 2 2 2 T-complex protein 11 MFS_1 PF07690.11 CDO77684.1 - 1.8e-06 26.9 23.1 4.7e-05 22.2 16.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Esterase_phd PF10503.4 CDO77685.1 - 2e-22 79.5 0.4 3.9e-22 78.5 0.3 1.4 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 CDO77685.1 - 7.9e-10 38.3 0.8 1.5e-09 37.4 0.6 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDO77685.1 - 2.4e-08 33.8 0.2 3.1e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO77685.1 - 3.3e-05 23.8 0.8 8.9e-05 22.4 0.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO77685.1 - 0.00058 19.4 0.0 0.00088 18.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CDO77685.1 - 0.0022 16.8 0.1 0.0022 16.8 0.1 1.7 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CDO77685.1 - 0.1 12.1 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Mg_trans_NIPA PF05653.9 CDO77686.1 - 3.9e-16 58.8 6.8 5.4e-11 41.9 2.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 CDO77686.1 - 0.017 15.1 17.2 0.23 11.5 0.2 3.2 3 0 0 3 3 3 0 EamA-like transporter family Hepatitis_core PF00906.15 CDO77686.1 - 0.31 10.6 2.4 0.59 9.7 1.7 1.4 1 0 0 1 1 1 0 Hepatitis core antigen Internalin_N PF12354.3 CDO77686.1 - 0.35 10.5 3.3 2.4 7.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal DUF1761 PF08570.5 CDO77686.1 - 3.5 7.6 12.4 0.18 11.8 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) DUF262 PF03235.9 CDO77687.1 - 2.8e-14 53.6 1.7 3.6e-13 50.0 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function DUF262 DUF2036 PF09724.4 CDO77688.1 - 1.4e-48 165.7 0.0 1e-25 90.5 0.0 2.0 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2036) p450 PF00067.17 CDO77690.1 - 1.8e-62 211.3 1.4 2e-52 178.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Cation_efflux PF01545.16 CDO77691.1 - 1.3e-47 162.2 5.4 3.4e-47 160.8 3.8 1.7 1 1 0 1 1 1 1 Cation efflux family CPSF73-100_C PF11718.3 CDO77691.1 - 5.9 6.1 6.9 44 3.3 2.9 2.2 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF3415 PF11895.3 CDO77692.1 - 1.6e-35 120.8 1.3 3.1e-35 119.8 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 CDO77692.1 - 3e-23 82.5 0.0 4.5e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Caleosin PF05042.8 CDO77693.1 - 1.5e-60 203.7 0.0 1.9e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 CDO77693.1 - 0.098 12.5 0.9 8.5 6.5 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain MFS_1 PF07690.11 CDO77695.1 - 1.1e-19 70.3 48.3 3.9e-14 52.1 21.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Asparaginase_2 PF01112.13 CDO77696.1 - 2.1e-52 177.8 0.0 1.1e-43 149.2 0.0 2.3 2 1 0 2 2 2 2 Asparaginase Malate_DH PF12434.3 CDO77696.1 - 0.064 12.9 0.4 0.13 11.9 0.3 1.5 1 0 0 1 1 1 0 Malate dehydrogenase enzyme G_glu_transpept PF01019.16 CDO77696.1 - 0.1 11.0 0.7 0.16 10.4 0.1 1.6 2 0 0 2 2 2 0 Gamma-glutamyltranspeptidase Dynamitin PF04912.9 CDO77699.1 - 1.2e-18 67.0 13.0 3.5e-12 45.8 0.1 3.6 2 1 1 3 3 3 2 Dynamitin SlyX PF04102.7 CDO77699.1 - 0.00045 20.5 5.0 1.5 9.2 0.3 4.1 3 1 0 3 3 3 2 SlyX CENP-F_leu_zip PF10473.4 CDO77699.1 - 0.067 13.0 13.6 2.8 7.7 2.2 4.2 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 CDO77699.1 - 0.083 12.6 4.8 1.6 8.5 0.1 3.4 2 1 1 3 3 3 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 CDO77699.1 - 0.099 12.3 5.7 0.047 13.4 1.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 CDO77699.1 - 0.13 11.8 2.6 4 6.9 0.4 3.0 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 CDO77699.1 - 0.14 11.9 4.0 0.23 11.2 0.6 2.8 2 2 0 2 2 2 0 Laminin Domain II Reo_sigmaC PF04582.7 CDO77699.1 - 0.17 11.0 2.3 0.46 9.6 0.1 2.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Rabaptin PF03528.10 CDO77699.1 - 0.23 11.4 3.9 2.2 8.2 0.8 2.8 2 0 0 2 2 2 0 Rabaptin Phasin PF05597.6 CDO77699.1 - 0.39 10.4 7.1 14 5.4 0.6 3.5 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1664 PF07889.7 CDO77699.1 - 0.41 10.4 2.4 0.83 9.4 0.1 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Matrilin_ccoil PF10393.4 CDO77699.1 - 0.9 8.9 4.9 2.8 7.3 0.0 3.9 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin COG2 PF06148.6 CDO77699.1 - 1.3 8.8 5.8 0.34 10.7 0.7 2.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 CDO77699.1 - 2.4 7.7 13.0 0.23 11.0 1.6 3.2 2 1 0 3 3 3 0 IncA protein Fmp27_WPPW PF10359.4 CDO77699.1 - 2.6 6.3 5.1 6.3 5.0 0.3 2.2 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Tropomyosin_1 PF12718.2 CDO77699.1 - 2.7 7.8 17.7 2.3 8.0 0.1 3.8 4 0 0 4 4 4 0 Tropomyosin like Lebercilin PF15619.1 CDO77699.1 - 4.2 6.7 15.0 0.29 10.5 2.4 3.0 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF1192 PF06698.6 CDO77699.1 - 5.4 6.9 11.5 0.28 10.9 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Tropomyosin PF00261.15 CDO77699.1 - 7.5 5.5 19.8 0.87 8.6 0.1 3.7 4 0 0 4 4 4 0 Tropomyosin Apc15p PF05841.6 CDO77699.1 - 7.8 7.2 8.7 2.3 8.9 3.2 2.2 2 1 0 2 2 2 0 Apc15p protein Hydrolase_like PF13242.1 CDO77700.1 - 3.6e-24 84.2 0.1 8.6e-24 83.0 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CDO77700.1 - 0.00027 20.7 0.0 0.00054 19.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CDO77700.1 - 0.0012 19.0 0.0 0.0036 17.5 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Pex24p PF06398.6 CDO77701.1 - 3.4e-22 78.7 5.7 1.8e-21 76.3 0.0 2.3 1 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Ank_2 PF12796.2 CDO77702.1 - 1.3e-23 83.1 0.0 7.6e-11 42.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CDO77702.1 - 4.5e-21 73.5 3.1 5.2e-08 32.3 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 CDO77702.1 - 1.3e-14 54.2 0.1 0.00015 22.2 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDO77702.1 - 2.7e-14 51.8 0.2 0.0012 18.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CDO77702.1 - 6e-11 42.2 0.6 0.00033 20.8 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) YiaAB PF05360.9 CDO77703.1 - 8 6.1 11.0 5.8 6.5 0.1 3.5 4 0 0 4 4 4 0 yiaA/B two helix domain DUF2207 PF09972.4 CDO77704.1 - 1.6 7.1 3.7 2.5 6.5 2.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4062 PF13271.1 CDO77705.1 - 0.013 15.5 1.9 20 5.2 0.0 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4062) DUF3106 PF11304.3 CDO77705.1 - 0.019 15.3 4.2 0.049 14.0 2.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) ApoO PF09769.4 CDO77705.1 - 0.028 14.1 1.0 0.072 12.8 0.6 1.7 1 1 0 1 1 1 0 Apolipoprotein O L1R_F9L PF02442.12 CDO77705.1 - 0.049 13.1 0.3 0.11 11.9 0.2 1.7 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Tho2 PF11262.3 CDO77705.1 - 0.27 10.2 4.2 0.62 9.0 2.9 1.7 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 4HB_MCP_1 PF12729.2 CDO77705.1 - 0.97 8.7 10.4 0.29 10.4 4.9 1.8 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF743 PF05332.6 CDO77705.1 - 1.2 9.1 6.9 4.3 7.3 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF743) V_ATPase_I PF01496.14 CDO77705.1 - 1.9 6.2 8.1 1.2 6.9 0.2 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Peptidase_S49_N PF08496.5 CDO77705.1 - 2 8.1 6.8 4.3 7.1 4.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Bacillus_HBL PF05791.6 CDO77705.1 - 7.3 5.9 13.7 1.2 8.5 3.8 2.7 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ADH_zinc_N PF00107.21 CDO77707.1 - 3.6e-24 84.7 0.1 7.7e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDO77707.1 - 6.7e-13 49.6 0.0 1.3e-12 48.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDO77707.1 - 1.4e-06 28.0 0.0 5.7e-06 26.0 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain APG5 PF04106.7 CDO77708.1 - 2.8e-48 164.0 0.0 3.9e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF218 PF02698.12 CDO77709.1 - 0.00012 21.6 0.1 0.00028 20.3 0.0 1.6 1 1 0 1 1 1 1 DUF218 domain HECT PF00632.20 CDO77710.1 - 6.1e-96 321.2 0.0 1e-95 320.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 CDO77710.1 - 5.4e-83 278.8 0.0 5.4e-83 278.8 0.0 4.3 6 0 0 6 6 6 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 CDO77710.1 - 1.8e-67 228.0 0.2 8.1e-67 225.8 0.1 2.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 CDO77710.1 - 3.3e-29 100.9 4.6 3.3e-29 100.9 3.2 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 CDO77710.1 - 2.3e-09 36.8 0.0 6.6e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Motilin_ghrelin PF04644.7 CDO77710.1 - 0.00094 18.9 0.4 0.0022 17.7 0.2 1.7 1 0 0 1 1 1 1 Motilin/ghrelin PC4 PF02229.11 CDO77711.1 - 2.8e-23 80.9 0.4 4.7e-23 80.1 0.3 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) ABC1 PF03109.11 CDO77712.1 - 1.7e-31 108.6 0.0 3.4e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CDO77712.1 - 2e-05 24.0 0.3 0.00011 21.5 0.1 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CDO77712.1 - 0.024 14.3 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 CDO77712.1 - 0.09 11.9 0.1 0.33 10.0 0.1 1.9 1 1 0 1 1 1 0 Protein kinase domain RabGAP-TBC PF00566.13 CDO77713.1 - 2.9e-53 180.5 0.4 5.1e-53 179.7 0.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CENP-F_leu_zip PF10473.4 CDO77713.1 - 0.00032 20.5 7.3 0.00058 19.7 5.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.1 CDO77713.1 - 0.0011 18.8 8.6 0.0023 17.8 6.0 1.5 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 DivIVA PF05103.8 CDO77713.1 - 0.0038 17.2 4.4 0.023 14.7 3.3 2.1 2 0 0 2 2 2 1 DivIVA protein APG6 PF04111.7 CDO77713.1 - 0.048 12.7 4.1 0.075 12.0 2.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CDO77713.1 - 0.11 12.1 7.8 0.2 11.2 5.4 1.3 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 CDO77713.1 - 0.22 11.0 3.7 0.41 10.1 2.6 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 CDO77713.1 - 0.34 10.7 1.2 0.66 9.7 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TAF PF02969.12 CDO77713.1 - 0.46 10.4 3.8 8.9 6.3 0.1 2.9 3 0 0 3 3 3 0 TATA box binding protein associated factor (TAF) DnaJ PF00226.26 CDO77714.1 - 0.00027 20.5 0.0 0.00052 19.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Hydrolase PF00702.21 CDO77717.1 - 0.041 14.2 0.3 0.15 12.4 0.1 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Zn_clus PF00172.13 CDO77719.1 - 0.0025 17.7 6.3 0.0048 16.7 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_92 PF07971.7 CDO77720.1 - 2.6e-122 409.0 0.0 4.1e-122 408.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 MFS_1 PF07690.11 CDO77721.1 - 9.7e-31 106.7 32.5 2.9e-30 105.1 22.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily AAA PF00004.24 CDO77722.1 - 5.9e-12 45.9 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDO77722.1 - 0.0052 16.9 0.9 0.41 10.7 0.2 3.2 1 1 1 2 2 2 1 AAA domain ArgK PF03308.11 CDO77722.1 - 0.0085 14.9 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_30 PF13604.1 CDO77722.1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CDO77722.1 - 0.024 14.3 0.0 0.084 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Glyco_hydro_92 PF07971.7 CDO77723.1 - 4.9e-94 315.7 4.1 1.7e-52 178.7 0.4 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 MFS_1 PF07690.11 CDO77724.1 - 3.2e-05 22.8 23.7 0.0002 20.1 16.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DIOX_N PF14226.1 CDO77726.1 - 1.5e-13 51.3 0.0 2.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CDO77726.1 - 4.9e-10 39.5 0.0 1.1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L28 PF00830.14 CDO77727.1 - 1.6e-23 82.3 0.8 2e-23 81.9 0.6 1.2 1 0 0 1 1 1 1 Ribosomal L28 family Iso_dh PF00180.15 CDO77728.1 - 3.1e-72 243.4 0.0 3.8e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans PF04082.13 CDO77729.1 - 9.3e-21 73.8 0.0 2e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CDO77729.1 - 0.00018 21.3 14.0 0.00034 20.4 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GWT1 PF06423.7 CDO77730.1 - 1.5e-35 122.2 0.0 4.1e-35 120.8 0.0 1.8 1 1 0 1 1 1 1 GWT1 UNC-50 PF05216.8 CDO77730.1 - 0.2 10.8 9.8 1 8.4 0.3 3.4 3 0 0 3 3 3 0 UNC-50 family AA_permease_2 PF13520.1 CDO77731.1 - 7.1e-41 140.1 52.7 8.8e-41 139.8 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CDO77731.1 - 3.5e-19 68.4 45.1 6e-19 67.7 31.2 1.3 1 1 0 1 1 1 1 Amino acid permease Thaumatin PF00314.12 CDO77734.1 - 5.5e-47 159.9 2.7 1.3e-46 158.7 1.9 1.5 1 1 0 1 1 1 1 Thaumatin family Glucan_synthase PF02364.10 CDO77735.1 - 0 1372.7 0.0 0 1372.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CDO77735.1 - 2.7e-38 130.4 0.0 6.9e-38 129.1 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Kdo PF06293.9 CDO77736.1 - 1.7e-05 24.0 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CDO77736.1 - 3.1e-05 23.2 0.0 5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CDO77736.1 - 0.0023 17.7 0.0 0.0072 16.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 CDO77736.1 - 0.14 11.2 0.0 0.3 10.2 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase Exo_endo_phos_2 PF14529.1 CDO77737.1 - 8.1e-09 35.1 0.2 1.7e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CDO77737.1 - 3.6e-06 27.1 2.7 7e-06 26.1 1.9 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Prenyltrans PF00432.16 CDO77737.1 - 0.026 14.1 1.5 0.069 12.7 1.0 1.8 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat DUF77 PF01910.12 CDO77737.1 - 0.028 14.0 0.1 0.071 12.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF77 MRI PF15325.1 CDO77738.1 - 0.12 13.3 0.4 0.22 12.4 0.3 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection TMEM154 PF15102.1 CDO77739.1 - 0.0089 15.7 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF4446 PF14584.1 CDO77739.1 - 0.03 14.1 0.2 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Pkinase PF00069.20 CDO77740.1 - 4.7e-58 196.3 0.4 3.2e-48 164.1 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77740.1 - 7.4e-25 87.4 0.3 5e-23 81.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CDO77740.1 - 0.00014 21.7 0.1 0.024 14.3 0.0 2.7 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.9 CDO77740.1 - 0.00039 19.5 0.0 0.00085 18.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CDO77740.1 - 0.018 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PACT_coil_coil PF10495.4 CDO77740.1 - 0.028 14.3 0.1 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF3415 PF11895.3 CDO77741.1 - 1.4e-32 111.3 3.8 1.8e-32 111.0 1.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 CDO77741.1 - 1.2e-23 83.8 0.0 2e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase AAA PF00004.24 CDO77742.1 - 1e-14 54.8 0.0 5.1e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDO77742.1 - 0.019 15.1 0.2 0.23 11.6 0.0 2.5 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CDO77742.1 - 0.054 13.8 0.0 0.37 11.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain Yae1_N PF09811.4 CDO77743.1 - 0.0013 18.2 3.3 0.0022 17.5 2.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Effector_1 PF04518.7 CDO77743.1 - 0.051 12.5 2.1 0.073 12.0 1.4 1.1 1 0 0 1 1 1 0 Effector from type III secretion system IncA PF04156.9 CDO77743.1 - 5.1 6.6 10.7 8.1 5.9 7.4 1.2 1 0 0 1 1 1 0 IncA protein Exo_endo_phos PF03372.18 CDO77744.1 - 6.3e-12 45.9 0.5 7.3e-12 45.7 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CDO77744.1 - 0.041 13.5 0.0 0.37 10.4 0.0 2.3 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase TB2_DP1_HVA22 PF03134.14 CDO77745.1 - 5.1e-26 90.2 5.6 7e-26 89.7 3.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Man-6-P_recep PF02157.10 CDO77745.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Ferritin_2 PF13668.1 CDO77746.1 - 1.6e-45 154.4 0.0 2.1e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain BRO1 PF03097.13 CDO77747.1 - 3.5e-115 384.7 0.6 4.9e-115 384.2 0.4 1.2 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CDO77747.1 - 2e-60 204.2 4.5 3.7e-60 203.4 3.1 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV eIF-5_eIF-2B PF01873.12 CDO77748.1 - 6.3e-47 158.3 0.2 9.5e-47 157.7 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 CDO77748.1 - 0.007 15.6 0.3 0.014 14.6 0.2 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding SR-25 PF10500.4 CDO77748.1 - 0.0072 15.8 0.8 0.013 15.0 0.6 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-HYPF PF07503.7 CDO77748.1 - 0.76 9.2 3.9 12 5.4 0.0 2.9 4 0 0 4 4 4 0 HypF finger Arc_trans_TRASH PF08394.5 CDO77748.1 - 2 8.6 4.5 18 5.6 0.0 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain ATP-synt PF00231.14 CDO77749.1 - 1.6e-65 221.3 9.6 1.9e-39 135.7 1.0 2.0 1 1 1 2 2 2 2 ATP synthase Catalase PF00199.14 CDO77750.1 - 4.6e-157 522.6 1.2 6.2e-94 314.8 0.0 2.1 2 0 0 2 2 2 2 Catalase Catalase-rel PF06628.7 CDO77750.1 - 1.2e-15 57.0 0.0 3.2e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Ribonucleas_3_3 PF14622.1 CDO77751.1 - 1.3e-11 44.5 0.0 5.9e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease-III-like Fe_hyd_SSU PF02256.12 CDO77751.1 - 0.2 11.6 1.9 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Iron hydrogenase small subunit Peptidase_S9 PF00326.16 CDO77752.1 - 7.9e-46 155.9 0.0 1.2e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDO77752.1 - 1.1e-10 41.4 0.0 2.4e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO77752.1 - 4.9e-06 26.5 0.0 2.9e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CDO77752.1 - 1.6e-05 24.3 0.0 3.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 CDO77752.1 - 9.1e-05 22.0 0.1 0.18 11.2 0.0 3.3 3 1 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 CDO77752.1 - 0.00023 20.7 0.0 0.17 11.4 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 CDO77752.1 - 0.00085 18.9 0.0 0.037 13.6 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 CDO77752.1 - 0.0024 17.7 0.0 0.0081 16.0 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Esterase_phd PF10503.4 CDO77752.1 - 0.0083 15.3 0.0 0.025 13.8 0.0 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 CDO77752.1 - 0.04 13.3 0.1 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative esterase FSH1 PF03959.8 CDO77752.1 - 0.056 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PHD PF00628.24 CDO77753.1 - 0.0024 17.5 0.9 0.057 13.1 0.2 2.3 2 0 0 2 2 2 2 PHD-finger Nup54 PF13874.1 CDO77754.1 - 2.3e-35 121.3 2.8 2.3e-35 121.3 1.9 1.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 CDO77754.1 - 8.6e-34 116.1 180.4 1.1e-12 48.1 27.5 5.1 1 1 3 4 4 4 4 Nucleoporin FG repeat region Taq-exonuc PF09281.5 CDO77755.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Taq polymerase, exonuclease DUF3416 PF11896.3 CDO77755.1 - 0.11 12.4 0.6 0.43 10.5 0.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3416) Pkinase PF00069.20 CDO77756.1 - 4.5e-17 62.0 0.0 4.6e-13 48.9 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77756.1 - 2.2e-05 23.6 0.1 0.00011 21.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 CDO77758.1 - 7.8e-12 44.8 0.0 3.4e-10 39.5 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77758.1 - 0.017 14.2 0.9 0.14 11.2 0.1 2.5 2 1 1 3 3 3 0 Protein tyrosine kinase Pkinase PF00069.20 CDO77759.1 - 4.7e-13 48.8 0.0 1.6e-10 40.5 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77759.1 - 0.0021 17.1 0.2 0.021 13.8 0.1 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase WD40 PF00400.27 CDO77760.1 - 1e-21 75.9 0.5 1e-08 34.6 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Ferritin_2 PF13668.1 CDO77761.1 - 2.4e-32 111.7 0.0 3.4e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.1 CDO77762.1 - 1.8e-33 115.3 0.1 2.4e-33 114.9 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain hSac2 PF12456.3 CDO77762.1 - 0.16 11.3 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Inositol phosphatase Ribosomal_L27e PF01777.13 CDO77763.1 - 1.8e-36 124.1 1.9 2.6e-36 123.5 1.3 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CDO77763.1 - 0.0036 16.9 0.3 0.014 15.0 0.2 2.1 1 0 0 1 1 1 1 KOW motif SUI1 PF01253.17 CDO77763.1 - 0.1 12.3 2.6 0.26 11.1 0.6 2.3 2 1 0 2 2 2 0 Translation initiation factor SUI1 Zn_clus PF00172.13 CDO77764.1 - 0.061 13.2 9.9 0.11 12.4 6.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4246 PF14033.1 CDO77764.1 - 0.081 11.5 1.2 0.085 11.4 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) TSA PF03249.8 CDO77764.1 - 0.3 9.5 4.5 0.37 9.2 3.1 1.1 1 0 0 1 1 1 0 Type specific antigen DUF755 PF05501.6 CDO77764.1 - 0.95 9.5 5.5 1.3 9.0 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF3886 PF13025.1 CDO77764.1 - 1.1 9.2 16.4 2 8.4 11.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) ATP-synt_E PF05680.7 CDO77764.1 - 1.3 9.0 7.9 1.8 8.5 5.5 1.3 1 0 0 1 1 1 0 ATP synthase E chain DUF972 PF06156.8 CDO77764.1 - 1.4 9.3 5.6 2.2 8.6 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Peptidase_S49_N PF08496.5 CDO77764.1 - 2.5 7.8 7.2 3.3 7.4 5.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal U79_P34 PF03064.11 CDO77764.1 - 3.2 7.1 7.6 3.7 7.0 5.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Vfa1 PF08432.5 CDO77764.1 - 5.3 7.0 13.9 7.4 6.5 9.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BTV_NS2 PF04514.7 CDO77764.1 - 6.3 5.5 11.2 7.7 5.2 7.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 IncA PF04156.9 CDO77764.1 - 6.6 6.2 8.0 8.9 5.8 5.6 1.2 1 0 0 1 1 1 0 IncA protein CDC27 PF09507.5 CDO77764.1 - 7.6 5.6 14.1 9.9 5.2 9.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 CDO77764.1 - 8 4.2 12.9 10 3.8 8.9 1.0 1 0 0 1 1 1 0 Nop14-like family Retrotrans_gag PF03732.12 CDO77765.1 - 6.3e-10 38.9 0.0 1.9e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2_2 PF14227.1 CDO77765.1 - 0.047 13.2 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type ATP-synt_G PF04718.10 CDO77766.1 - 1.7e-19 70.4 0.2 7.4e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Retrotrans_gag PF03732.12 CDO77769.1 - 0.00016 21.6 0.5 0.00016 21.6 0.3 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein RVT_1 PF00078.22 CDO77770.1 - 3.3e-17 62.5 0.0 5e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO77770.1 - 1.1e-13 51.6 0.0 1.9e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO77770.1 - 0.00068 19.9 0.1 0.0015 18.8 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Arrestin_N PF00339.24 CDO77771.1 - 1.5e-09 37.8 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CDO77771.1 - 0.039 13.4 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 Arrestin_N terminal like Arrestin_C PF02752.17 CDO77772.1 - 1.8e-11 44.2 0.0 2.9e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain zf-MYND PF01753.13 CDO77774.1 - 0.069 13.0 2.7 0.18 11.7 1.9 1.6 1 0 0 1 1 1 0 MYND finger Glyco_hydro_3 PF00933.16 CDO77775.1 - 5.4e-72 242.3 0.0 1.2e-71 241.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CDO77775.1 - 1.9e-68 230.4 0.1 3.2e-67 226.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CDO77775.1 - 3.3e-22 78.2 0.6 6.3e-22 77.2 0.4 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 CDO77775.1 - 2.7e-15 56.2 0.0 5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Aldo_ket_red PF00248.16 CDO77776.1 - 9.4e-72 241.1 0.0 1.1e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 CDO77777.1 - 3.4e-72 242.6 0.0 3.9e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 CDO77778.1 - 2.2e-71 240.0 0.0 2.5e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 2OG-FeII_Oxy_3 PF13640.1 CDO77780.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CDO77780.1 - 0.078 12.6 0.0 0.4 10.3 0.0 2.2 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily LRR_6 PF13516.1 CDO77781.1 - 1.4e-07 30.8 4.4 8.1 6.8 0.0 8.1 8 1 0 8 8 8 1 Leucine Rich repeat LRR_8 PF13855.1 CDO77781.1 - 4.8e-05 23.0 2.5 3.4 7.4 0.2 5.1 4 2 0 4 4 4 2 Leucine rich repeat LRR_7 PF13504.1 CDO77781.1 - 0.00024 20.7 5.2 60 4.5 0.0 7.1 7 0 0 7 7 7 0 Leucine rich repeat FAD_binding_9 PF08021.6 CDO77781.1 - 0.00057 19.8 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain LRR_1 PF00560.28 CDO77781.1 - 0.0014 18.4 3.7 57 4.3 0.0 6.5 7 1 1 8 8 8 0 Leucine Rich Repeat Sigma70_ner PF04546.8 CDO77782.1 - 0.01 15.4 4.0 0.02 14.5 2.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region LAT PF15234.1 CDO77782.1 - 0.015 14.7 1.7 0.026 14.0 1.2 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells RRN3 PF05327.6 CDO77782.1 - 0.33 9.0 1.6 0.41 8.7 1.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2890 PF11081.3 CDO77782.1 - 0.88 9.6 7.5 0.21 11.6 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) PBP1_TM PF14812.1 CDO77782.1 - 1.1 9.6 5.4 0.77 10.1 1.9 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 CDO77782.1 - 1.2 8.2 9.1 0.86 8.7 5.3 1.5 1 1 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 CDO77782.1 - 2.9 8.1 11.3 6.8 7.0 7.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3505 PF12013.3 CDO77783.1 - 0.0011 19.1 8.7 0.003 17.7 6.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) TB PF00683.12 CDO77783.1 - 0.19 11.3 1.5 0.41 10.2 1.0 1.5 1 0 0 1 1 1 0 TB domain rve PF00665.21 CDO77784.1 - 4.9e-23 81.5 0.0 8.9e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO77784.1 - 1.8e-07 30.6 0.1 3.4e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FlxA PF14282.1 CDO77785.1 - 0.64 9.9 7.8 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 FlxA-like protein RP-C_C PF11800.3 CDO77785.1 - 2.9 7.5 14.1 3.6 7.2 2.4 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region SPX PF03105.14 CDO77785.1 - 4.4 7.0 13.5 3.1 7.5 1.9 2.0 2 0 0 2 2 2 0 SPX domain IL34 PF15036.1 CDO77786.1 - 0.14 11.6 0.2 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Interleukin 34 RVT_1 PF00078.22 CDO77787.1 - 1.7e-07 30.8 0.1 8.8e-07 28.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CDO77787.1 - 0.00011 21.2 0.5 0.00017 20.6 0.4 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4 PF00097.20 CDO77790.1 - 2.2e-05 24.0 1.5 3.5e-05 23.3 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDO77790.1 - 3.2e-05 23.6 0.7 6.6e-05 22.6 0.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CDO77790.1 - 0.00014 21.6 0.4 0.00021 21.0 0.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CDO77790.1 - 0.00018 21.4 0.8 0.00018 21.4 0.6 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CDO77790.1 - 0.00059 19.3 0.3 0.0018 17.7 0.1 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 CDO77790.1 - 0.0058 16.2 0.5 0.01 15.5 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDO77790.1 - 0.0074 15.9 0.2 0.012 15.2 0.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 CDO77790.1 - 0.026 14.6 0.9 0.042 13.9 0.6 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 CDO77790.1 - 0.054 13.3 0.3 0.074 12.8 0.2 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CDO77790.1 - 0.17 11.6 1.8 0.34 10.6 1.0 1.7 1 1 1 2 2 2 0 zinc-RING finger domain Retrotrans_gag PF03732.12 CDO77791.1 - 1e-12 47.9 0.0 3.7e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO77791.1 - 0.011 15.5 0.3 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle UBN2_2 PF14227.1 CDO77791.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Macoilin PF09726.4 CDO77791.1 - 3.9 5.6 9.9 5.6 5.1 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Myb_DNA-bind_3 PF12776.2 CDO77796.1 - 0.00039 20.9 0.0 0.0016 19.0 0.0 2.1 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Peptidase_S9 PF00326.16 CDO77798.1 - 1.9e-44 151.4 0.2 3.5e-44 150.5 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDO77798.1 - 6.4e-12 45.4 0.0 1.6e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDO77798.1 - 1.6e-07 31.4 0.6 1.7e-06 28.0 0.2 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 CDO77798.1 - 0.0003 19.3 0.1 0.0024 16.4 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) TRI5 PF06330.6 CDO77799.1 - 0.00023 19.9 0.0 0.0003 19.5 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) RVT_1 PF00078.22 CDO77800.1 - 3.3e-10 39.6 0.5 5.8e-08 32.3 0.0 2.6 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CDO77800.1 - 1.3e-09 37.6 0.0 2.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CDO77800.1 - 6.8e-05 23.0 0.0 0.00073 19.8 0.0 2.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 CDO77800.1 - 0.00091 19.5 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 RNase H zf-CCHC_6 PF15288.1 CDO77800.1 - 0.013 15.1 1.3 0.062 12.9 1.0 2.1 2 0 0 2 2 2 0 Zinc knuckle ERM PF00769.14 CDO77800.1 - 0.084 12.3 3.0 0.15 11.5 2.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Laminin_II PF06009.7 CDO77800.1 - 0.17 11.6 0.1 0.34 10.6 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain II rve PF00665.21 CDO77801.1 - 1.6e-22 79.8 0.3 6.7e-22 77.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CDO77801.1 - 2.5e-09 36.6 0.3 5.5e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 CDO77801.1 - 2.7e-09 36.5 0.0 1.3e-08 34.3 0.1 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO77801.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 CDO77801.1 - 0.025 14.1 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain UBN2_3 PF14244.1 CDO77801.1 - 0.14 11.6 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 CDO77801.1 - 0.87 9.3 2.5 1.8 8.3 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3295 PF11702.3 CDO77803.1 - 0.073 12.0 0.8 0.25 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) DUF111 PF01969.12 CDO77803.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF111 Helicase_C PF00271.26 CDO77804.1 - 6.6e-13 48.3 0.0 2.1e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO77804.1 - 1.1e-05 24.9 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC_6 PF15288.1 CDO77804.1 - 2.7e-05 23.7 1.2 6.1e-05 22.6 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle AhpC-TSA_2 PF13911.1 CDO77804.1 - 0.0016 18.3 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AAA_14 PF13173.1 CDO77804.1 - 0.063 13.1 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DDE_3 PF13358.1 CDO77805.1 - 3.6e-25 88.4 0.0 7.3e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease PAP2 PF01569.16 CDO77805.1 - 1.5e-13 50.5 2.0 7.8e-12 44.9 1.4 2.8 1 1 0 1 1 1 1 PAP2 superfamily HTH_Tnp_Tc3_2 PF01498.13 CDO77805.1 - 4.6e-07 29.8 4.4 1.9e-06 27.8 0.7 3.1 3 0 0 3 3 3 1 Transposase rve PF00665.21 CDO77805.1 - 0.019 15.1 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Fungal_trans_2 PF11951.3 CDO77805.1 - 0.11 11.1 1.1 0.18 10.3 0.8 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain TilS_C PF11734.3 CDO77805.1 - 4.1 6.7 8.3 0.94 8.7 0.5 2.9 3 0 0 3 3 3 0 TilS substrate C-terminal domain PSD4 PF07631.6 CDO77807.1 - 0.059 13.7 0.1 0.11 12.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) Ribonuclease PF00545.15 CDO77808.1 - 0.066 13.2 0.5 0.4 10.7 0.2 2.2 2 0 0 2 2 2 0 ribonuclease RNase_H PF00075.19 CDO77810.1 - 3e-14 53.4 0.0 5.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 CDO77810.1 - 1.8e-13 50.3 0.0 3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CDO77810.1 - 0.0045 17.2 0.0 0.0099 16.1 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase BH3 PF15285.1 CDO77810.1 - 0.086 12.3 0.2 0.3 10.6 0.1 2.0 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Abhydrolase_6 PF12697.2 CDO77811.1 - 1.3e-20 74.2 0.1 1.6e-20 74.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDO77811.1 - 8e-16 57.6 0.0 1.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 CDO77811.1 - 2.7e-14 53.1 0.0 4.4e-14 52.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 CDO77811.1 - 0.023 13.1 0.0 0.18 10.2 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 CDO77811.1 - 0.046 12.9 0.0 0.6 9.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.11 CDO77812.1 - 7.7e-30 103.7 54.5 2.7e-29 101.9 37.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO77812.1 - 1.5e-21 76.2 18.4 2.8e-21 75.3 12.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hydrolase_4 PF12146.3 CDO77813.1 - 2.6e-15 56.0 0.1 4.8e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 CDO77813.1 - 2.8e-13 50.2 0.1 4.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO77813.1 - 2.5e-12 46.7 0.0 5.1e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 CDO77813.1 - 0.0019 16.7 0.0 1.2 7.5 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) YqzM PF14141.1 CDO77814.1 - 0.2 11.4 0.0 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 YqzM-like protein APH PF01636.18 CDO77815.1 - 9e-13 48.5 0.0 7.9e-12 45.4 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family ICMT PF04140.9 CDO77816.1 - 5.9e-13 48.8 1.8 7.1e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDO77816.1 - 2.9e-12 46.6 4.7 4.5e-12 46.0 0.3 2.7 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 CDO77816.1 - 0.00047 18.8 0.3 0.00068 18.2 0.2 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CDO77816.1 - 0.072 12.3 0.2 0.13 11.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) p450 PF00067.17 CDO77817.1 - 6.4e-37 127.1 0.0 2.8e-36 125.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 CDO77818.1 - 9.1e-16 57.5 22.5 1.6e-09 36.9 11.4 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily CcmD PF04995.9 CDO77819.1 - 4.1 7.2 7.2 7.7 6.3 0.3 2.8 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) RUN PF02759.14 CDO77825.1 - 0.015 15.0 0.0 0.058 13.1 0.0 2.0 2 1 0 2 2 2 0 RUN domain GRAB PF10375.4 CDO77827.1 - 2.6e-06 26.8 0.6 5e-06 25.9 0.4 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.15 CDO77827.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 GRIP domain LPP PF04728.8 CDO77827.1 - 0.073 12.8 7.7 0.34 10.7 0.5 2.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper CLPTM1 PF05602.7 CDO77827.1 - 0.53 8.9 7.1 0.74 8.4 4.9 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1054 PF06335.7 CDO77827.1 - 1.4 8.5 7.2 0.32 10.6 1.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1054) F-box-like PF12937.2 CDO77828.1 - 6.4e-07 29.0 0.1 6.4e-07 29.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 CDO77828.1 - 0.12 12.0 0.0 3.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) APH PF01636.18 CDO77830.1 - 8.8e-15 55.0 0.4 2.3e-14 53.6 0.3 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDO77830.1 - 5.4e-08 32.6 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 CDO77830.1 - 0.032 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.9 CDO77830.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MAD PF05557.8 CDO77832.1 - 3.1e-49 167.7 62.8 4.1e-49 167.3 43.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Reo_sigmaC PF04582.7 CDO77832.1 - 1.5 7.9 20.8 2.8 7.0 5.7 3.3 1 1 1 3 3 3 0 Reovirus sigma C capsid protein USP8_interact PF08941.5 CDO77832.1 - 8.3 5.6 14.5 0.21 10.8 0.3 3.7 2 2 2 4 4 4 0 USP8 interacting DUF262 PF03235.9 CDO77833.1 - 1.8e-14 54.2 0.2 5.7e-14 52.6 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF262 Peptidase_S64 PF08192.6 CDO77834.1 - 0.00061 18.2 0.0 0.00093 17.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 PilJ PF13675.1 CDO77834.1 - 0.41 10.9 3.8 0.25 11.6 1.0 1.8 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term TPR_11 PF13414.1 CDO77835.1 - 8.8e-17 60.5 11.4 2e-13 49.7 3.6 2.9 2 1 2 4 4 4 3 TPR repeat TPR_2 PF07719.12 CDO77835.1 - 1.2e-09 37.3 8.0 0.00027 20.6 2.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDO77835.1 - 6e-08 31.9 3.9 0.06 12.9 1.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDO77835.1 - 2.2e-05 25.0 24.9 0.00082 19.9 2.4 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CDO77835.1 - 0.00011 22.4 6.4 0.15 12.4 1.9 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat zf-CCCH PF00642.19 CDO77835.1 - 0.00039 20.0 11.2 0.056 13.1 0.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_9 PF13371.1 CDO77835.1 - 0.00042 20.0 4.8 0.00042 20.0 3.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDO77835.1 - 0.0021 18.0 3.2 7.5 7.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDO77835.1 - 0.01 16.4 0.4 0.01 16.4 0.3 5.6 4 1 3 7 7 5 0 Tetratricopeptide repeat PAM2 PF07145.10 CDO77835.1 - 0.019 14.4 0.1 0.086 12.3 0.0 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region TPR_12 PF13424.1 CDO77835.1 - 0.039 13.8 11.4 0.28 11.1 3.7 3.3 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDO77835.1 - 0.055 13.2 1.1 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CDO77835.1 - 0.24 11.5 3.3 1.2 9.3 1.4 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CDO77835.1 - 0.47 10.4 3.5 4.3 7.3 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.2 CDO77836.1 - 0.0047 16.6 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like Phage_integrase PF00589.17 CDO77837.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family RVT_1 PF00078.22 CDO77838.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 CDO77838.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Methyltransf_23 PF13489.1 CDO77840.1 - 8.8e-09 35.2 0.0 1.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDO77840.1 - 1.9e-07 30.4 0.0 2.4e-06 26.8 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CDO77840.1 - 3e-07 30.8 0.0 6.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO77840.1 - 5.7e-07 29.9 0.0 4.2e-06 27.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO77840.1 - 1e-05 26.0 0.3 0.00022 21.7 0.1 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO77840.1 - 1.1e-05 25.7 0.0 3e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO77840.1 - 2.8e-05 23.7 0.0 0.00028 20.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO77840.1 - 0.0047 16.9 0.0 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 CDO77840.1 - 0.05 11.9 0.0 0.65 8.2 0.0 2.2 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 CDO77840.1 - 0.093 13.5 0.0 0.21 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CDO77840.1 - 0.14 11.0 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family EF-hand_1 PF00036.27 CDO77841.1 - 2.8e-24 82.5 0.2 7.2e-06 24.9 0.0 4.7 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CDO77841.1 - 4.1e-22 76.0 0.2 3.9e-06 26.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CDO77841.1 - 5.2e-19 66.6 0.6 0.0003 19.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDO77841.1 - 1.3e-18 66.8 1.8 6.1e-09 35.8 0.2 2.7 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CDO77841.1 - 3.7e-16 58.4 0.8 9e-08 31.6 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 CDO77841.1 - 0.0039 17.0 0.0 2.5 8.0 0.0 3.2 3 1 0 3 3 3 1 EF-hand domain Toprim_2 PF13155.1 CDO77841.1 - 0.021 15.1 0.0 15 5.9 0.0 2.7 1 1 2 3 3 3 0 Toprim-like EF-hand_2 PF09068.6 CDO77841.1 - 0.047 13.7 0.0 34 4.5 0.0 3.3 3 1 1 4 4 4 0 EF hand MRI PF15325.1 CDO77842.1 - 0.34 11.8 2.5 0.47 11.4 1.5 1.4 1 1 0 1 1 1 0 Modulator of retrovirus infection Transposase_21 PF02992.9 CDO77845.1 - 1.6e-16 60.1 0.0 9.1e-16 57.6 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 RVT_1 PF00078.22 CDO77846.1 - 2.1e-17 63.1 0.0 3.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO77846.1 - 1.5e-09 38.2 0.0 3.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 CDO77846.1 - 0.00025 20.6 0.2 0.19 11.3 0.0 2.6 1 1 1 2 2 2 2 Endonuclease-reverse transcriptase Med25_VWA PF11265.3 CDO77846.1 - 0.077 12.0 0.0 9.8 5.1 0.0 3.0 3 0 0 3 3 3 0 Mediator complex subunit 25 von Willebrand factor type A Helicase_C PF00271.26 CDO77848.1 - 1.4e-10 40.9 0.0 3.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDO77848.1 - 2.1e-10 40.3 0.2 1.1e-09 38.0 0.2 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CDO77848.1 - 2.2e-06 27.6 0.0 6.2e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CDO77848.1 - 0.00028 19.8 0.1 0.00051 18.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1272 PF06906.6 CDO77848.1 - 0.28 11.0 1.6 0.57 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Transaldolase PF00923.14 CDO77851.1 - 0.11 11.5 0.0 9.4 5.2 0.0 2.1 1 1 0 2 2 2 0 Transaldolase PGM_PMM_II PF02879.11 CDO77852.1 - 3.6e-20 72.2 0.0 9.7e-20 70.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 CDO77852.1 - 3.9e-16 58.7 0.0 8.2e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CDO77852.1 - 1.2e-14 54.2 0.0 2.3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CDO77852.1 - 8.9e-06 25.6 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain BHD_3 PF10405.4 CDO77852.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 Racemase_4 PF13615.1 CDO77853.1 - 2.9e-18 65.9 0.1 5.9e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 CDO77853.1 - 9.2e-08 31.6 0.0 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Myb_DNA-bind_4 PF13837.1 CDO77854.1 - 2.2e-09 37.2 0.1 4.2e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO77854.1 - 2.5e-06 28.0 0.1 4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO77854.1 - 2.2e-05 24.2 0.0 6.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO77854.1 - 0.0075 16.3 0.1 0.02 15.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sigma70_ner PF04546.8 CDO77854.1 - 0.17 11.4 4.1 0.08 12.5 1.3 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Myb_DNA-binding PF00249.26 CDO77854.1 - 0.3 11.1 1.8 0.59 10.2 0.7 2.1 2 1 0 2 2 2 0 Myb-like DNA-binding domain CENP-B_dimeris PF09026.5 CDO77854.1 - 0.78 10.0 8.9 1.7 8.9 6.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DDE_Tnp_4 PF13359.1 CDO77855.1 - 6.4e-12 45.3 0.0 1.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CDO77855.1 - 5.5e-05 22.6 0.1 8.3e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO77855.1 - 0.00043 20.4 0.1 0.00097 19.2 0.1 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.16 CDO77855.1 - 0.065 12.7 0.0 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain UVR PF02151.14 CDO77855.1 - 0.23 11.0 2.3 0.5 9.9 1.6 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif Nop10p PF04135.7 CDO77856.1 - 0.096 12.4 0.1 0.26 11.0 0.1 1.8 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family Myb_DNA-bind_3 PF12776.2 CDO77857.1 - 2.1e-07 31.5 0.0 5.4e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Asp PF00026.18 CDO77858.1 - 1.1e-11 44.5 0.1 1.8e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp PF00026.18 CDO77859.1 - 7.1e-17 61.6 1.9 1e-14 54.4 1.3 3.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CDO77859.1 - 2.2e-08 34.4 1.8 7.3e-08 32.8 0.3 2.4 3 0 0 3 3 3 1 Aspartyl protease zf-MYND PF01753.13 CDO77861.1 - 2.8e-11 43.0 15.4 4.4e-11 42.4 10.7 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 CDO77861.1 - 1 9.0 7.6 1.5 8.5 5.3 1.3 1 0 0 1 1 1 0 HIT zinc finger PNP_UDP_1 PF01048.15 CDO77863.1 - 4.8e-39 133.7 0.1 6.2e-39 133.3 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily RVT_2 PF07727.9 CDO77864.1 - 2.1e-88 295.4 0.0 3e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CDO77864.1 - 0.0017 17.7 0.1 0.032 13.5 0.1 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_21 PF02992.9 CDO77865.1 - 5e-13 48.6 0.0 1.2e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 RVT_2 PF07727.9 CDO77867.1 - 4.9e-25 87.9 0.0 7.8e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO77867.1 - 1.1e-06 28.7 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RD3 PF14473.1 CDO77867.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 RD3 protein DDE_Tnp_4 PF13359.1 CDO77868.1 - 4.2e-23 81.6 0.0 5.2e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CDO77868.1 - 0.0036 16.6 0.0 0.0063 15.9 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 CDO77868.1 - 0.007 15.9 0.1 0.026 14.0 0.1 1.8 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 CDO77868.1 - 0.021 15.0 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 CDO77869.1 - 2.2e-05 25.0 0.3 4.1e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CDO77869.1 - 0.00011 22.2 0.3 0.00036 20.6 0.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pap_E4 PF02711.9 CDO77869.1 - 2.2 9.1 5.2 4 8.3 0.7 2.7 2 1 0 2 2 2 0 E4 protein ATP_bind_1 PF03029.12 CDO77870.1 - 1.2e-71 240.9 0.0 1.5e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 CDO77870.1 - 0.069 13.0 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDO77870.1 - 0.13 13.0 7.4 0.056 14.2 1.8 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CDO77870.1 - 0.19 11.6 0.7 1.9 8.4 0.5 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase GST_N_3 PF13417.1 CDO77871.1 - 1.2e-13 51.0 0.0 2.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO77871.1 - 6.1e-08 32.5 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO77871.1 - 0.00017 21.7 0.0 0.00059 19.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO77871.1 - 0.0099 15.7 0.3 0.02 14.7 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldo_ket_red PF00248.16 CDO77872.1 - 1.8e-63 214.0 0.0 2.5e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 CDO77873.1 - 9.8e-71 237.8 0.0 1.1e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CMAS PF02353.15 CDO77875.1 - 3.5e-65 219.8 0.0 4.3e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CDO77875.1 - 1.4e-13 50.8 0.1 1.6e-12 47.4 0.1 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDO77875.1 - 1.2e-09 38.4 0.0 7.5e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO77875.1 - 3e-07 31.0 0.0 9.3e-07 29.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDO77875.1 - 4.4e-07 30.2 0.0 9.8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO77875.1 - 7.3e-06 25.9 0.1 0.00019 21.4 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDO77875.1 - 4.6e-05 23.7 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDO77875.1 - 5.8e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 CDO77875.1 - 0.00015 21.1 0.0 0.00036 19.9 0.0 1.5 2 0 0 2 2 2 1 Histone methylation protein DOT1 MTS PF05175.9 CDO77875.1 - 0.0029 16.9 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 CDO77875.1 - 0.0083 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 CDO77875.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain YIF1 PF03878.10 CDO77876.1 - 4e-79 265.1 1.5 5e-79 264.8 1.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 CDO77876.1 - 0.33 10.4 13.4 0.45 9.9 8.7 1.7 1 1 0 1 1 1 0 Yip1 domain rve PF00665.21 CDO77878.1 - 1.9e-22 79.6 0.3 6.6e-22 77.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CDO77878.1 - 2.5e-09 36.6 0.3 5.4e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 CDO77878.1 - 2.7e-09 36.6 0.0 1.3e-08 34.4 0.1 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO77878.1 - 0.00057 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 CDO77878.1 - 0.024 14.1 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain UBN2_3 PF14244.1 CDO77878.1 - 0.16 11.5 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 CDO77878.1 - 0.85 9.3 2.5 1.8 8.3 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 CDO77880.1 - 1.6e-22 79.9 0.0 3.6e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEAD PF00270.24 CDO77881.1 - 3.1e-17 62.5 0.0 6.7e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDO77881.1 - 0.00011 22.1 0.0 0.00025 20.9 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CDO77881.1 - 0.00013 20.8 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDO77881.1 - 0.00064 19.5 0.0 0.018 14.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 CDO77881.1 - 0.08 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain Methyltransf_25 PF13649.1 CDO77885.1 - 4.5e-06 26.9 0.0 1.2e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO77885.1 - 0.0039 16.9 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ATP_bind_1 PF03029.12 CDO77889.1 - 1.2e-71 240.9 0.0 1.5e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 CDO77889.1 - 0.069 13.0 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDO77889.1 - 0.13 13.0 7.4 0.056 14.2 1.8 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CDO77889.1 - 0.19 11.6 0.7 1.9 8.4 0.5 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase GST_N_3 PF13417.1 CDO77890.1 - 1.2e-13 51.0 0.0 2.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO77890.1 - 6.1e-08 32.5 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO77890.1 - 0.00017 21.7 0.0 0.00059 19.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO77890.1 - 0.0099 15.7 0.3 0.02 14.7 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DDE_3 PF13358.1 CDO77891.1 - 7e-14 51.8 0.2 7.6e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Peroxin-13_N PF04088.8 CDO77893.1 - 1.7e-43 148.3 0.0 3e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 CDO77893.1 - 1.3e-11 43.6 2.1 5.1e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CDO77893.1 - 7.5e-10 38.1 0.0 1.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CDO77893.1 - 2.5e-08 33.3 1.0 6.4e-08 32.0 0.7 1.7 1 1 0 1 1 1 1 Variant SH3 domain PIF1 PF05970.9 CDO77896.1 - 2e-113 379.0 0.0 2.7e-113 378.6 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 CDO77896.1 - 2.7e-60 203.2 0.1 5.6e-60 202.2 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 CDO77896.1 - 5.9e-06 25.9 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 CDO77896.1 - 0.0016 16.3 0.0 0.0025 15.6 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.1 CDO77896.1 - 0.0027 17.8 0.1 0.015 15.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 CDO77896.1 - 0.0064 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 CDO77896.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CDO77896.1 - 0.076 12.7 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 CDO77896.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 CDO77896.1 - 0.25 10.5 0.0 0.5 9.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF2791 PF10923.3 CDO77896.1 - 0.26 9.8 0.0 0.38 9.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) PSD4 PF07631.6 CDO77897.1 - 0.056 13.8 0.1 0.11 12.8 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1592) Peptidase_C48 PF02902.14 CDO77898.1 - 0.004 16.8 0.4 0.0064 16.1 0.3 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Zn_clus PF00172.13 CDO77899.1 - 0.023 14.6 7.2 0.04 13.8 5.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UBN_AB PF14075.1 CDO77899.1 - 0.19 11.3 0.0 0.19 11.3 0.0 2.8 3 0 0 3 3 3 0 Ubinuclein conserved middle domain ScpA_ScpB PF02616.9 CDO77899.1 - 6 6.3 10.5 8.3 5.9 0.1 2.2 2 0 0 2 2 2 0 ScpA/B protein rve PF00665.21 CDO77900.1 - 6e-20 71.5 0.0 1.1e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO77900.1 - 5.2e-08 32.4 0.0 9.4e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ferrochelatase PF00762.14 CDO77900.1 - 0.016 14.2 0.1 1.1 8.1 0.0 2.2 1 1 1 2 2 2 0 Ferrochelatase Transposase_21 PF02992.9 CDO77902.1 - 2.7e-15 56.1 0.0 5.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO77902.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RVT_1 PF00078.22 CDO77903.1 - 4.2e-20 72.0 0.0 7.4e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO77903.1 - 1.3e-13 51.4 0.0 2.4e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 CDO77903.1 - 0.0028 17.9 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase MFS_1 PF07690.11 CDO77904.1 - 1.8e-24 86.1 56.4 9.3e-16 57.4 17.3 3.3 2 2 1 3 3 3 2 Major Facilitator Superfamily MBOAT_2 PF13813.1 CDO77904.1 - 2e-07 30.9 1.1 1.8e-06 27.8 0.2 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Sugar_tr PF00083.19 CDO77904.1 - 0.00049 18.7 31.0 0.026 13.1 4.8 3.8 4 0 0 4 4 4 3 Sugar (and other) transporter DAD PF02109.11 CDO77904.1 - 1.7 8.7 6.1 0.51 10.4 0.7 2.7 3 0 0 3 3 3 0 DAD family p450 PF00067.17 CDO77905.1 - 8.5e-65 219.0 0.0 8.1e-64 215.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 M20_dimer PF07687.9 CDO77905.1 - 1.6e-06 27.8 0.0 4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Epimerase PF01370.16 CDO77906.1 - 6e-52 176.4 0.0 8.5e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CDO77906.1 - 6.3e-07 28.5 0.0 2.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CDO77906.1 - 5.2e-06 25.5 0.8 0.00057 18.8 0.5 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CDO77906.1 - 0.011 14.4 0.0 0.022 13.5 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CDO77907.1 - 1e-67 228.0 0.0 1.3e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CDO77907.1 - 4.1e-06 25.9 0.0 7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CDO77907.1 - 0.0059 15.5 0.0 0.0094 14.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CDO77907.1 - 0.042 13.0 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 CDO77907.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Epimerase_Csub PF13950.1 CDO77907.1 - 0.087 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit MFS_1 PF07690.11 CDO77908.1 - 1.9e-40 138.7 60.0 8.4e-32 110.2 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDO77908.1 - 2.2e-07 29.6 22.6 2.7e-07 29.3 13.6 2.2 1 1 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.19 CDO77908.1 - 3.1e-06 26.0 16.0 3.1e-06 26.0 11.1 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 CDO77908.1 - 0.63 9.8 12.7 0.35 10.7 2.1 3.7 4 0 0 4 4 4 0 MFS_1 like family Pkinase PF00069.20 CDO77909.1 - 0.0021 17.2 0.0 0.0038 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 CDO77909.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RVT_1 PF00078.22 CDO77910.1 - 8.6e-28 97.1 0.0 1.4e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CDO77910.1 - 3.5e-19 68.5 0.0 7.9e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 CDO77910.1 - 3.7e-13 49.9 0.0 7.4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 CDO77910.1 - 1e-06 28.9 0.1 2.5e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 CDO77911.1 - 0.0033 17.2 4.2 0.0033 17.2 2.9 3.2 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDO77911.1 - 0.0072 15.9 0.3 0.0072 15.9 0.2 3.6 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 CDO77911.1 - 1.7 8.3 6.7 0.22 11.2 1.4 2.0 2 0 0 2 2 2 0 Zinc knuckle Med25_VWA PF11265.3 CDO77913.1 - 0.0049 15.9 0.0 0.0099 14.9 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Hid1 PF12722.2 CDO77913.1 - 1 6.9 2.3 1.6 6.3 1.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macro_2 PF14519.1 CDO77914.1 - 0.00035 19.7 0.1 0.0014 17.8 0.1 1.8 1 1 0 1 1 1 1 Macro-like domain p450 PF00067.17 CDO77915.1 - 9e-12 44.2 0.0 1e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.13 CDO77916.1 - 2.7e-47 161.3 0.0 3.4e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 CDO77916.1 - 2.2e-14 52.8 6.7 2.2e-14 52.8 4.7 2.9 4 0 0 4 4 4 1 Fungal cellulose binding domain Ribosomal_L30 PF00327.15 CDO77917.1 - 9.3e-13 47.5 0.9 1.2e-12 47.1 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PTCB-BRCT PF12738.2 CDO77918.1 - 2.7e-22 78.4 0.0 8.5e-15 54.3 0.0 3.1 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.21 CDO77918.1 - 4.4e-10 39.5 0.0 1.5e-05 25.0 0.0 3.5 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PITH PF06201.8 CDO77919.1 - 1e-38 132.4 0.0 1.3e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain GST_C_3 PF14497.1 CDO77923.1 - 9.5e-06 26.0 0.0 1.7e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO77923.1 - 0.00041 20.1 0.0 0.0015 18.3 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain zf-RING_2 PF13639.1 CDO77924.1 - 3.7e-07 29.8 6.2 3.7e-07 29.8 4.3 2.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 CDO77924.1 - 1.3e-06 28.0 13.5 4.8e-06 26.2 3.7 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CDO77924.1 - 2.3e-06 27.5 7.1 2.3e-06 27.5 4.9 3.3 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDO77924.1 - 3.1e-05 23.5 3.9 3.1e-05 23.5 2.7 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO77924.1 - 0.00029 20.4 5.1 0.00029 20.4 3.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDO77924.1 - 0.0016 18.5 1.9 0.0016 18.5 1.3 2.3 3 0 0 3 3 3 1 RING-H2 zinc finger zf-Nse PF11789.3 CDO77924.1 - 0.0053 16.2 2.1 0.0053 16.2 1.4 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CDO77924.1 - 0.01 15.5 2.0 0.01 15.5 1.4 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CDO77924.1 - 0.02 14.6 1.4 0.056 13.2 0.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CDO77924.1 - 0.37 10.6 13.7 0.048 13.5 4.3 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING XPA_N PF01286.13 CDO77924.1 - 8.6 6.1 8.3 0.63 9.7 0.4 2.7 3 0 0 3 3 3 0 XPA protein N-terminal Brix PF04427.13 CDO77925.1 - 5.7e-38 130.4 0.1 7.2e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain zf-RING_2 PF13639.1 CDO77926.1 - 3.4e-07 29.9 7.3 7.5e-07 28.8 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDO77926.1 - 5e-07 29.6 7.2 9e-07 28.8 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDO77926.1 - 5.9e-06 25.9 7.3 1.2e-05 24.9 5.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CDO77926.1 - 1.9e-05 24.2 5.4 3.3e-05 23.4 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDO77926.1 - 0.00021 20.9 6.8 0.00041 19.9 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDO77926.1 - 0.0011 18.7 7.8 0.0025 17.6 5.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CDO77926.1 - 0.0011 18.6 1.8 0.0011 18.6 1.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger MAD PF05557.8 CDO77926.1 - 0.0014 16.7 12.7 0.0017 16.5 8.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF2120 PF09893.4 CDO77926.1 - 0.042 13.7 2.3 0.5 10.2 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF342 PF03961.8 CDO77926.1 - 0.046 12.1 5.4 0.057 11.8 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4427 PF14468.1 CDO77926.1 - 0.12 12.0 0.7 0.27 10.9 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4427) zf-MIZ PF02891.15 CDO77926.1 - 0.14 11.7 5.8 0.31 10.6 4.0 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 CDO77926.1 - 0.14 11.9 2.5 0.28 11.0 1.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Borrelia_P83 PF05262.6 CDO77926.1 - 0.3 9.3 14.4 0.36 9.0 10.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Spc7 PF08317.6 CDO77926.1 - 0.31 9.6 10.2 0.46 9.1 7.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.8 CDO77926.1 - 1.4 8.8 0.0 1.4 8.8 0.0 3.0 2 2 1 3 3 3 0 Lipoprotein leucine-zipper zf-RING_4 PF14570.1 CDO77926.1 - 1.7 8.3 6.9 3.6 7.2 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2462 PF09495.5 CDO77926.1 - 2.2 9.0 9.3 0.1 13.3 1.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2462) NOB1_Zn_bind PF08772.6 CDO77926.1 - 3.1 7.6 6.8 8.1 6.3 0.9 2.8 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like FliD_N PF02465.13 CDO77926.1 - 6 7.3 7.5 14 6.1 0.2 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus KH_1 PF00013.24 CDO77928.1 - 2.3e-40 136.0 7.9 9.1e-14 50.8 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CDO77928.1 - 2.1e-30 103.7 13.0 6.3e-10 38.4 0.1 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CDO77928.1 - 1.3e-15 56.6 7.7 3.9e-06 26.3 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CDO77928.1 - 3.7e-05 23.2 2.1 0.26 10.9 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 CDO77928.1 - 0.016 14.9 5.5 12 5.8 0.0 3.5 3 0 0 3 3 3 0 NusA-like KH domain Stm1_N PF09598.5 CDO77929.1 - 7.1 7.4 8.8 0.23 12.1 1.2 2.2 2 0 0 2 2 2 0 Stm1 CPDase PF07823.6 CDO77930.1 - 4.3e-11 42.6 0.9 1e-06 28.4 0.0 2.9 1 1 1 2 2 2 2 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 CDO77930.1 - 0.00048 19.8 0.7 0.016 14.9 0.5 2.3 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily RHH_2 PF03693.9 CDO77930.1 - 0.05 13.7 0.4 0.083 13.0 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0156) DUF1776 PF08643.5 CDO77931.1 - 2.5e-15 56.3 0.0 5.1e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF883 PF05957.8 CDO77931.1 - 0.014 15.7 0.1 0.088 13.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TRAM_LAG1_CLN8 PF03798.11 CDO77932.1 - 1.6e-29 102.8 12.4 1.6e-29 102.8 8.6 1.8 2 0 0 2 2 2 1 TLC domain DDE_3 PF13358.1 CDO77934.1 - 7.1e-13 48.5 0.0 4.7e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 CDO77935.1 - 2.5e-20 72.5 0.1 6.7e-13 48.2 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease Aldedh PF00171.17 CDO77936.1 - 5.2e-59 199.8 0.0 9e-37 126.4 0.0 2.9 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 CDO77936.1 - 4.1e-05 22.4 0.0 0.07 11.8 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) p450 PF00067.17 CDO77937.1 - 1.1e-33 116.4 0.1 6.3e-32 110.6 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.9 CDO77940.1 - 3.7e-39 134.7 0.0 4.7e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RVT_2 PF07727.9 CDO77941.1 - 1.9e-33 115.4 0.1 2.7e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) P22_Tail-4 PF11650.3 CDO77941.1 - 0.014 14.9 0.1 0.032 13.8 0.1 1.6 1 0 0 1 1 1 0 P22 tail accessory factor T2SL PF05134.8 CDO77942.1 - 0.03 13.4 1.7 0.065 12.4 1.2 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L Asp PF00026.18 CDO77943.1 - 3.9e-75 253.0 8.7 4.5e-75 252.8 6.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO77943.1 - 6.6e-09 35.9 0.3 1.2e-08 35.1 0.2 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO77943.1 - 0.013 16.0 0.4 0.083 13.4 0.1 2.5 3 1 0 3 3 3 0 Aspartyl protease TAXi_C PF14541.1 CDO77943.1 - 0.015 14.8 0.2 0.056 12.9 0.1 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Exo_endo_phos PF03372.18 CDO77944.1 - 0.052 13.4 2.2 0.085 12.7 1.0 1.6 1 1 1 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Rnk_N PF14760.1 CDO77946.1 - 0.15 12.1 2.8 7 6.8 0.3 2.6 2 0 0 2 2 2 0 Rnk N-terminus Mito_carr PF00153.22 CDO77947.1 - 1e-33 114.8 0.0 2.6e-17 62.2 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein Ribosomal_60s PF00428.14 CDO77947.1 - 0.0068 16.7 3.6 0.0068 16.7 2.5 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein YtxH PF12732.2 CDO77947.1 - 0.031 14.6 1.0 0.064 13.6 0.7 1.6 1 0 0 1 1 1 0 YtxH-like protein Arrestin_N PF00339.24 CDO77950.1 - 0.0024 17.7 0.0 0.0099 15.6 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DDE_Tnp_4 PF13359.1 CDO77951.1 - 7.1e-14 51.6 0.0 1.6e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 CDO77951.1 - 0.0046 16.3 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO77951.1 - 0.025 14.7 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 CDO77952.1 - 2.1e-05 25.0 0.3 4.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CDO77952.1 - 0.00023 21.2 0.4 0.00062 19.8 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Pap_E4 PF02711.9 CDO77952.1 - 2.2 9.1 5.2 4 8.3 0.7 2.7 2 1 0 2 2 2 0 E4 protein NUDIX PF00293.23 CDO77954.1 - 1.3e-05 24.8 0.1 3.2e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain FA_desaturase PF00487.19 CDO77955.1 - 6.4e-28 97.8 14.9 1e-27 97.2 10.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 CDO77955.1 - 1e-17 63.0 0.4 1.7e-17 62.3 0.3 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) zf-C2H2_4 PF13894.1 CDO77956.1 - 0.031 14.6 0.2 0.064 13.6 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CDO77956.1 - 0.15 12.4 0.3 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Na_trans_assoc PF06512.8 CDO77956.1 - 4 7.3 7.8 9 6.1 5.4 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Pkinase PF00069.20 CDO77957.1 - 1.7e-61 207.6 0.0 2.1e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO77957.1 - 1.9e-26 92.7 0.0 2.5e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO77957.1 - 0.082 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like NARP1 PF12569.3 CDO77958.1 - 9.6e-171 569.0 3.9 4.8e-168 560.1 0.1 2.9 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 CDO77958.1 - 2.1e-19 68.9 9.1 1.1e-05 25.0 0.3 6.8 5 1 1 6 6 6 4 TPR repeat TPR_16 PF13432.1 CDO77958.1 - 2.1e-17 63.2 34.1 5.2e-06 26.9 0.6 9.9 8 3 3 11 11 10 5 Tetratricopeptide repeat TPR_2 PF07719.12 CDO77958.1 - 2.8e-16 58.0 13.0 0.003 17.3 0.0 9.1 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 CDO77958.1 - 2.5e-13 50.1 25.9 0.018 15.4 0.1 8.8 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 CDO77958.1 - 6.6e-13 47.6 2.1 0.00043 19.7 0.2 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CDO77958.1 - 1.4e-11 44.4 0.3 0.018 15.1 0.0 5.3 3 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CDO77958.1 - 2.2e-10 40.3 10.7 0.00019 21.3 0.1 6.1 4 1 4 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 CDO77958.1 - 2.7e-10 39.9 31.4 0.00014 22.1 0.1 11.7 8 2 6 14 14 12 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDO77958.1 - 4.2e-07 29.7 12.7 0.83 9.5 0.2 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CDO77958.1 - 1.4e-06 27.6 8.0 0.038 13.8 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 CDO77958.1 - 2.9e-06 27.1 9.1 0.017 15.4 0.3 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDO77958.1 - 2.2e-05 24.3 3.9 4.6 7.6 0.0 7.1 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDO77958.1 - 6.6e-05 23.0 10.6 16 6.2 0.0 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.1 CDO77958.1 - 0.0046 16.8 3.7 1.9 8.5 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDO77958.1 - 0.0049 16.5 1.0 0.52 10.2 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDO77958.1 - 0.0057 16.5 6.2 0.28 11.0 0.0 5.0 5 1 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat DUF3366 PF11846.3 CDO77958.1 - 0.044 13.6 2.2 1.2 8.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) PPR_1 PF12854.2 CDO77958.1 - 0.17 11.3 0.7 1.9 8.0 0.1 2.8 3 0 0 3 3 3 0 PPR repeat PPR PF01535.15 CDO77958.1 - 0.18 11.8 0.0 22 5.2 0.0 3.7 3 0 0 3 3 3 0 PPR repeat BTAD PF03704.12 CDO77958.1 - 1.1 9.5 13.5 0.95 9.7 0.7 4.6 5 1 0 5 5 4 0 Bacterial transcriptional activator domain HEAT_2 PF13646.1 CDO77959.1 - 0.00014 22.0 9.3 0.0019 18.4 0.1 4.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CDO77959.1 - 0.059 13.4 10.8 1.7 8.9 0.0 6.2 7 0 0 7 7 7 0 HEAT repeat FANCI_S2 PF14676.1 CDO77959.1 - 0.18 11.7 4.0 10 6.0 0.0 2.8 2 0 0 2 2 2 0 FANCI solenoid 2 Hid1 PF12722.2 CDO77959.1 - 1.6 6.3 5.8 2.7 5.5 4.0 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cauli_AT PF03233.8 CDO77960.1 - 0.93 9.1 4.4 0.78 9.4 0.1 2.5 2 1 0 2 2 2 0 Aphid transmission protein DUF3807 PF12720.2 CDO77960.1 - 7.7 6.6 11.2 2.8 8.0 5.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3807) IncA PF04156.9 CDO77961.1 - 0.00015 21.4 3.3 0.00015 21.4 2.3 2.9 2 1 1 3 3 3 1 IncA protein Baculo_PEP_C PF04513.7 CDO77961.1 - 0.0035 17.1 1.8 1.6 8.5 0.1 2.7 2 1 0 3 3 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 CDO77961.1 - 0.012 15.7 0.4 26 5.1 0.0 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 CDO77961.1 - 0.013 15.3 13.1 0.055 13.3 0.4 2.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HR1 PF02185.11 CDO77961.1 - 0.051 13.3 5.6 0.064 13.0 0.1 3.2 3 0 0 3 3 3 0 Hr1 repeat Retrotrans_gag PF03732.12 CDO77961.1 - 0.053 13.6 5.6 0.21 11.6 0.8 3.6 3 2 0 3 3 3 0 Retrotransposon gag protein Polysacc_synt PF01943.12 CDO77961.1 - 0.055 12.7 0.1 0.082 12.1 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3450 PF11932.3 CDO77961.1 - 0.073 12.3 0.2 0.073 12.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3584 PF12128.3 CDO77961.1 - 0.076 10.3 10.5 0.19 8.9 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) Phage_lysis PF03245.8 CDO77961.1 - 0.079 12.9 13.5 0.51 10.3 2.3 3.1 3 1 0 3 3 3 0 Bacteriophage Rz lysis protein Bacillus_HBL PF05791.6 CDO77961.1 - 0.21 10.9 12.4 0.93 8.8 0.6 3.5 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF1049 PF06305.6 CDO77961.1 - 0.34 10.3 0.1 0.34 10.3 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) Prefoldin_2 PF01920.15 CDO77961.1 - 0.35 10.6 16.2 0.28 10.9 1.1 3.6 3 1 0 3 3 3 0 Prefoldin subunit Ax_dynein_light PF10211.4 CDO77961.1 - 0.48 10.2 9.7 1.5 8.6 0.1 3.0 3 0 0 3 3 3 0 Axonemal dynein light chain DUF4446 PF14584.1 CDO77961.1 - 1 9.1 7.7 3.5 7.4 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Rootletin PF15035.1 CDO77961.1 - 1.1 9.2 10.0 1.2 9.0 1.6 3.3 3 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion PPE PF00823.14 CDO77961.1 - 1.2 8.9 6.4 25 4.6 0.7 3.5 3 2 2 5 5 5 0 PPE family Snapin_Pallidin PF14712.1 CDO77961.1 - 1.3 9.3 8.4 5.8 7.2 0.4 3.3 3 0 0 3 3 2 0 Snapin/Pallidin V-SNARE PF05008.10 CDO77961.1 - 1.5 9.0 10.5 0.6 10.3 0.8 3.7 3 1 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Spc24 PF08286.6 CDO77961.1 - 1.6 8.4 7.1 6.1 6.5 0.3 2.9 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Adeno_PIX PF03955.9 CDO77961.1 - 1.7 9.2 5.6 13 6.3 0.4 3.0 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) TPR_MLP1_2 PF07926.7 CDO77961.1 - 1.8 8.3 16.1 0.076 12.7 1.6 3.4 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Syntaxin PF00804.20 CDO77961.1 - 2.2 8.4 9.6 4 7.6 0.4 3.9 3 1 1 4 4 4 0 Syntaxin IFP_35_N PF07334.8 CDO77961.1 - 2.3 8.2 4.5 0.84 9.6 0.7 2.2 2 0 0 2 2 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus HAUS-augmin3 PF14932.1 CDO77961.1 - 2.8 7.0 11.1 5.8 6.0 0.5 3.1 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 GAS PF13851.1 CDO77961.1 - 3.8 6.6 12.1 0.6 9.2 0.4 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Cep57_MT_bd PF06657.8 CDO77961.1 - 9.8 6.2 12.4 2.5 8.1 0.1 4.2 3 2 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Myosin_tail_1 PF01576.14 CDO77962.1 - 0.003 15.3 2.3 0.003 15.3 1.6 3.3 4 0 0 4 4 4 2 Myosin tail DUF972 PF06156.8 CDO77962.1 - 0.0032 17.7 3.0 0.0032 17.7 2.1 4.4 4 1 0 4 4 4 1 Protein of unknown function (DUF972) Shugoshin_N PF07558.6 CDO77962.1 - 0.014 15.0 3.1 0.19 11.4 1.6 2.9 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF904 PF06005.7 CDO77962.1 - 0.016 15.4 8.2 0.016 15.4 5.7 4.1 5 2 1 6 6 5 0 Protein of unknown function (DUF904) ATP-synt_E_2 PF08112.6 CDO77962.1 - 0.063 13.3 0.8 0.22 11.6 0.0 2.3 3 0 0 3 3 3 0 ATP synthase epsilon subunit BLOC1_2 PF10046.4 CDO77962.1 - 0.18 11.9 18.0 0.71 10.0 2.3 4.8 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Homeobox PF00046.24 CDO77962.1 - 0.77 9.4 2.9 1 9.0 0.4 2.5 3 0 0 3 3 3 0 Homeobox domain TSC22 PF01166.13 CDO77962.1 - 0.81 9.6 8.1 1.8 8.5 0.4 4.5 4 1 0 4 4 4 0 TSC-22/dip/bun family CLTH PF10607.4 CDO77962.1 - 0.86 9.2 7.6 0.13 12.0 0.2 2.7 2 1 1 3 3 3 0 CTLH/CRA C-terminal to LisH motif domain Mod_r PF07200.8 CDO77962.1 - 1.1 9.2 24.3 0.11 12.3 2.3 4.2 4 1 0 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Syntaxin PF00804.20 CDO77962.1 - 1.1 9.5 18.0 0.48 10.6 0.7 5.2 3 2 3 6 6 6 0 Syntaxin Prominin PF05478.6 CDO77962.1 - 1.4 6.3 22.6 0.66 7.4 3.1 3.1 1 1 1 2 2 2 0 Prominin GAS PF13851.1 CDO77962.1 - 1.5 7.9 19.3 0.03 13.4 2.9 3.9 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding XkdW PF09636.5 CDO77962.1 - 2.4 8.0 8.3 1.7 8.5 0.5 3.0 3 1 0 3 3 3 0 XkdW protein TBPIP PF07106.8 CDO77962.1 - 3.5 7.1 21.7 3.7 7.0 1.7 4.9 4 1 1 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 CDO77962.1 - 5.6 7.0 16.0 0.06 13.3 1.2 4.5 4 0 0 4 4 4 0 bZIP transcription factor DUF4201 PF13870.1 CDO77962.1 - 8.1 5.8 14.5 0.45 9.9 1.6 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4201) Ribosomal_L44 PF00935.14 CDO77963.1 - 1.8e-35 120.8 11.2 2.7e-35 120.1 7.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 MAP7 PF05672.6 CDO77964.1 - 0.48 9.7 48.6 0.28 10.5 6.2 2.4 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family rve PF00665.21 CDO77965.1 - 8.4e-23 80.7 0.0 1.6e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDO77965.1 - 9.6e-08 31.5 0.1 1.9e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CDO77965.1 - 0.00047 19.5 0.0 0.00085 18.6 0.0 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Imm47 PF15586.1 CDO77965.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 47 Asp_protease_2 PF13650.1 CDO77969.1 - 0.00095 19.6 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CDO77969.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.21 CDO77971.1 - 2.1e-06 27.8 0.0 3.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CDO77971.1 - 0.037 13.9 0.0 0.074 13.0 0.0 1.5 2 0 0 2 2 2 0 DDE domain RVT_1 PF00078.22 CDO77972.1 - 1.4e-26 93.2 0.0 2.2e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CDO77973.1 - 0.0014 18.6 0.3 0.0029 17.6 0.2 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Pinin_SDK_memA PF04696.8 CDO77975.1 - 0.024 14.2 4.7 0.052 13.1 3.3 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Transposase_21 PF02992.9 CDO77978.1 - 5.8e-15 55.0 0.0 4e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 CDO77978.1 - 0.012 15.0 0.2 0.028 13.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) RVT_2 PF07727.9 CDO77980.1 - 5.1e-30 104.2 0.0 1.1e-29 103.1 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_2 PF14227.1 CDO77982.1 - 5.4e-09 35.6 0.2 1e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO77982.1 - 0.0024 17.6 0.2 0.0078 15.9 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF2946 PF11162.3 CDO77982.1 - 0.0072 16.5 3.5 0.025 14.7 2.4 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) IL34 PF15036.1 CDO77983.1 - 0.004 16.7 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 Interleukin 34 McyA_C PF12593.3 CDO77984.1 - 0.089 12.5 0.6 0.23 11.2 0.4 1.6 1 0 0 1 1 1 0 Microcystin synthetase C terminal FYVE PF01363.16 CDO77985.1 - 0.017 14.9 0.4 0.04 13.8 0.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger Toprim_3 PF13362.1 CDO77985.1 - 0.06 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Toprim domain GSHPx PF00255.14 CDO77986.1 - 0.15 11.4 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Glutathione peroxidase UBN2_3 PF14244.1 CDO77987.1 - 1.2e-09 37.9 1.0 3e-09 36.6 0.7 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO77987.1 - 1.7e-09 36.8 1.3 3.1e-09 36.0 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Repressor_Mnt PF11423.3 CDO77987.1 - 0.039 13.2 0.1 0.13 11.6 0.1 1.8 1 1 0 1 1 1 0 Regulatory protein Mnt Eaf7 PF07904.8 CDO77987.1 - 0.046 13.7 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 Retrotrans_gag PF03732.12 CDO77988.1 - 7.8e-12 45.1 0.1 2.3e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO77988.1 - 0.011 15.5 0.3 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle UBN2 PF14223.1 CDO77988.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MFS_1 PF07690.11 CDO77989.1 - 5.4e-38 130.6 56.9 4e-37 127.7 39.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO77989.1 - 1.3e-25 89.6 21.3 1.7e-25 89.2 14.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CDO77989.1 - 3.6e-15 55.4 12.1 3.6e-15 55.4 8.4 3.4 2 2 0 3 3 3 1 Sugar (and other) transporter SUD-M PF11633.3 CDO77989.1 - 0.13 11.5 0.1 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain DDE_3 PF13358.1 CDO77990.1 - 2.5e-16 59.7 0.4 2.7e-16 59.6 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CDO77990.1 - 0.0013 18.7 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain SecY PF00344.15 CDO77991.1 - 2.1e-37 128.8 0.8 2.3e-37 128.7 0.5 1.0 1 0 0 1 1 1 1 SecY translocase Methyltransf_15 PF09445.5 CDO77992.1 - 2.6e-39 134.4 0.0 4.6e-28 97.8 0.0 2.1 1 1 1 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 CDO77992.1 - 2.6e-11 43.6 0.1 4.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDO77992.1 - 6.7e-09 36.3 0.0 1.3e-08 35.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CDO77992.1 - 1.8e-06 27.6 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 CDO77992.1 - 4.1e-06 27.0 0.0 7.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CDO77992.1 - 1.5e-05 24.4 0.0 3.9e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 CDO77992.1 - 4.9e-05 22.9 0.0 9.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CDO77992.1 - 6.9e-05 22.4 0.0 0.00015 21.3 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 CDO77992.1 - 0.0028 18.1 0.0 0.0067 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CDO77992.1 - 0.0035 16.0 0.0 0.0049 15.6 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.8 CDO77992.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.21 CDO77992.1 - 0.022 14.3 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CAML PF14963.1 CDO77996.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand rve PF00665.21 CDO77997.1 - 3.5e-09 36.7 0.0 6.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 CDO77997.1 - 0.0038 17.1 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 DDE domain DUF331 PF03889.8 CDO77997.1 - 0.061 12.6 0.3 0.15 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function Asp_protease_2 PF13650.1 CDO78000.1 - 0.0094 16.4 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CDO78000.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease DDE_3 PF13358.1 CDO78003.1 - 6.9e-13 48.5 0.0 8.2e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.17 CDO78004.1 - 5.6e-22 77.1 0.0 8.9e-12 44.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO78004.1 - 7.3e-19 67.5 0.0 1.4e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO78004.1 - 1.8e-09 37.3 0.0 5.9e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Enterotoxin_a PF01375.12 CDO78004.1 - 0.0039 16.5 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain DUF3433 PF11915.3 CDO78006.1 - 1.1e-09 38.2 0.3 1.1e-09 38.2 0.2 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3433) TPT PF03151.11 CDO78006.1 - 0.0091 15.6 3.4 0.07 12.7 0.4 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family MAGP PF05507.6 CDO78006.1 - 0.1 12.3 0.0 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) MutS_V PF00488.16 CDO78007.1 - 6.2e-98 326.8 0.0 1e-97 326.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CDO78007.1 - 8.6e-33 113.8 2.1 1.3e-32 113.2 0.7 1.9 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.13 CDO78007.1 - 2.2e-17 62.9 0.7 5.2e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 CDO78007.1 - 2.8e-16 59.8 0.0 1.4e-14 54.3 0.0 2.8 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 CDO78007.1 - 3.6e-09 36.6 0.0 8.7e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain I Med9 PF07544.8 CDO78007.1 - 0.13 12.0 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Pmp3 PF01679.12 CDO78008.1 - 1.5e-19 69.3 7.4 2.1e-19 68.9 5.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.3 CDO78008.1 - 0.071 12.8 0.9 0.11 12.2 0.7 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DDE_3 PF13358.1 CDO78009.1 - 2.6e-24 85.6 0.0 4.9e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 CDO78009.1 - 8.6e-07 29.6 0.4 2.6e-06 28.1 0.2 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CDO78009.1 - 1.9e-06 28.0 1.5 3.4e-06 27.1 0.5 1.8 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.21 CDO78009.1 - 1.5e-05 25.1 0.0 5.6e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_Tnp_Tc3_2 PF01498.13 CDO78009.1 - 7.8e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.1 CDO78009.1 - 0.079 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix BLVR PF06375.6 CDO78010.1 - 0.013 15.3 5.9 0.029 14.2 4.1 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) PAT1 PF09770.4 CDO78010.1 - 0.34 9.1 0.0 0.34 9.1 0.0 3.1 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 ERM PF00769.14 CDO78011.1 - 0.015 14.8 2.6 0.025 14.1 1.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1664 PF07889.7 CDO78011.1 - 0.14 11.9 0.2 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 CDO78012.1 - 0.21 10.6 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 CDO78013.1 - 0.002 17.3 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO78013.1 - 0.058 12.4 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Arrestin_N PF00339.24 CDO78015.1 - 7.1e-13 48.6 0.0 6.4e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CDO78015.1 - 2.3e-12 47.2 0.0 4.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain FMN_dh PF01070.13 CDO78016.1 - 5.1e-119 397.2 0.0 6.1e-119 397.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CDO78016.1 - 2.2e-23 81.8 0.0 7.8e-23 80.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CDO78016.1 - 2.9e-05 23.1 0.0 4.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CDO78016.1 - 0.00052 19.0 0.0 0.00094 18.1 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CDO78017.1 - 1.2e-118 396.0 0.0 1.5e-118 395.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CDO78017.1 - 6.5e-22 77.1 0.0 1.3e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 CDO78017.1 - 3.6e-05 22.8 0.1 0.00028 19.8 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 CDO78017.1 - 6.5e-05 22.0 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 CDO78017.1 - 0.025 13.6 0.1 2.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 CDO78017.1 - 0.093 11.6 0.1 3.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase PEP_mutase PF13714.1 CDO78018.1 - 1.4e-46 158.6 3.6 1.8e-46 158.3 2.5 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 CDO78018.1 - 1.8e-18 66.0 0.8 2.5e-18 65.6 0.5 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Hexapep PF00132.19 CDO78021.1 - 4.4e-13 48.0 17.5 6.9e-08 31.6 1.5 4.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CDO78021.1 - 2e-07 30.4 14.4 5.3e-06 25.8 2.8 3.7 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 CDO78021.1 - 0.0018 16.8 0.1 0.0027 16.3 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase TrkH PF02386.11 CDO78022.1 - 3.7e-93 311.9 10.6 1.8e-91 306.3 3.5 2.1 2 0 0 2 2 2 2 Cation transport protein Keratin_B2_2 PF13885.1 CDO78022.1 - 0.072 12.8 0.5 0.15 11.8 0.4 1.4 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Pkinase PF00069.20 CDO78023.1 - 0.073 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain LCM PF04072.9 CDO78025.1 - 1.2e-22 80.3 0.0 1.9e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Tim17 PF02466.14 CDO78026.1 - 4.9e-36 123.5 4.6 6.1e-36 123.2 3.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 CDO78026.1 - 0.0086 16.0 0.8 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF543) Bcl-2 PF00452.14 CDO78026.1 - 0.054 13.6 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family TSP9 PF11493.3 CDO78026.1 - 0.14 12.6 0.4 2.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 zf-C2H2 PF00096.21 CDO78029.1 - 0.26 11.6 7.0 0.13 12.6 2.8 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDO78029.1 - 0.33 11.3 4.6 0.81 10.1 3.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Lipase_2 PF01674.13 CDO78030.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) RVT_1 PF00078.22 CDO78031.1 - 8.4e-15 54.7 0.0 1.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CDO78031.1 - 2e-05 24.9 0.0 4.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 CDO78032.1 - 3.3e-21 75.6 0.0 7.2e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDO78032.1 - 1.2e-12 48.3 0.0 2.5e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 CDO78032.1 - 3.2e-11 42.8 0.0 1.1e-10 41.1 0.0 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.1 CDO78032.1 - 0.00036 20.7 0.0 0.00086 19.5 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase IncA PF04156.9 CDO78033.1 - 0.024 14.2 1.8 0.041 13.4 1.2 1.2 1 0 0 1 1 1 0 IncA protein ERM PF00769.14 CDO78033.1 - 0.11 12.0 1.9 0.16 11.5 1.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Herpes_UL25 PF01499.11 CDO78033.1 - 0.11 10.7 3.3 0.17 10.1 2.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DDE_3 PF13358.1 CDO78034.1 - 1.3e-14 54.1 0.0 5.6e-14 52.1 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease Asp PF00026.18 CDO78035.1 - 2.2e-51 175.0 6.5 2.6e-51 174.7 4.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDO78035.1 - 2.7e-09 37.1 0.4 4e-09 36.6 0.3 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CDO78035.1 - 0.028 14.8 0.1 0.08 13.4 0.1 1.8 1 1 0 1 1 1 0 Aspartyl protease Exo_endo_phos_2 PF14529.1 CDO78037.1 - 1.5e-08 34.2 0.1 3.8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 CDO78037.1 - 3.2e-05 23.9 9.6 5e-05 23.3 6.7 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF77 PF01910.12 CDO78038.1 - 0.0061 16.1 0.7 0.013 15.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF77 adh_short PF00106.20 CDO78039.1 - 1.4e-16 60.8 0.3 1.9e-16 60.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO78039.1 - 5.5e-06 26.1 0.1 9.8e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 CDO78039.1 - 0.0037 16.8 0.1 0.008 15.7 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus NAD_binding_10 PF13460.1 CDO78039.1 - 0.0054 16.7 0.4 0.012 15.6 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CDO78039.1 - 0.019 14.7 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CDO78039.1 - 0.038 13.4 0.0 0.091 12.1 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.18 CDO78039.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 CDO78039.1 - 0.11 12.9 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_1_2 PF00155.16 CDO78040.1 - 4.1e-34 118.0 0.0 1.3e-33 116.5 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CDO78040.1 - 0.0017 16.6 0.0 0.0027 16.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CDO78040.1 - 0.0042 15.8 0.0 0.18 10.5 0.0 2.4 3 0 0 3 3 3 1 Aminotransferase class-V OKR_DC_1 PF01276.15 CDO78040.1 - 0.0049 15.4 0.0 0.0066 15.0 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 CDO78040.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase PYC_OADA PF02436.13 CDO78040.1 - 0.17 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain Condensin2nSMC PF12422.3 CDO78041.1 - 0.11 12.2 0.5 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Lge1 PF11488.3 CDO78041.1 - 0.89 9.7 8.2 0.072 13.2 0.7 2.7 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 PIN_2 PF10130.4 CDO78041.1 - 2.1 8.3 4.5 1.2 9.1 1.2 1.9 1 1 1 2 2 2 0 PIN domain GCD14 PF08704.5 CDO78041.1 - 5.5 6.4 5.1 8.5 5.7 0.9 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DUF1183 PF06682.7 CDO78042.1 - 3.6e-64 217.3 0.0 7.2e-64 216.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) PROL5-SMR PF15621.1 CDO78042.1 - 0.91 9.9 7.1 0.54 10.7 2.9 2.1 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family adh_short PF00106.20 CDO78043.1 - 1.9e-15 57.1 0.0 8.5e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CDO78043.1 - 4.7e-06 26.3 0.0 3.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CDO78043.1 - 0.00089 19.0 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CDO78043.1 - 0.0016 18.4 0.0 0.0081 16.1 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CDO78043.1 - 0.046 12.6 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 CDO78043.1 - 0.049 13.0 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CDO78043.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FAM163 PF15069.1 CDO78044.1 - 0.0053 17.3 0.0 0.041 14.4 0.0 2.4 2 0 0 2 2 2 1 FAM163 family Herpes_gE PF02480.11 CDO78044.1 - 0.13 10.4 0.0 0.27 9.4 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CDO78044.1 - 0.21 12.0 0.2 0.59 10.5 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 CDO78044.1 - 0.47 10.1 0.0 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Amnionless PF14828.1 CDO78044.1 - 0.5 8.8 0.0 0.72 8.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless HNH_2 PF13391.1 CDO78046.1 - 5.5e-06 26.0 0.0 9.9e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease EF_assoc_2 PF08356.7 CDO78046.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 EF hand associated DUF2621 PF11084.3 CDO78047.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) DDE_1 PF03184.14 CDO78051.1 - 2e-08 33.6 0.0 8.3e-06 25.0 0.0 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CDO78051.1 - 0.00041 20.0 0.1 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain G-alpha PF00503.15 CDO78051.1 - 0.014 14.1 2.5 0.022 13.4 1.7 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Spore_coat_CotO PF14153.1 CDO78051.1 - 0.51 9.7 8.1 0.87 9.0 5.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Abhydrolase_6 PF12697.2 CDO78052.1 - 3.4e-25 89.2 2.4 4.1e-25 88.9 1.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDO78052.1 - 3e-05 23.8 0.0 0.00013 21.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CDO78052.1 - 0.054 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FA_desaturase PF00487.19 CDO78053.1 - 1.1e-23 84.0 17.6 1.1e-23 84.0 12.2 1.5 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 CDO78053.1 - 0.00099 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Abhydrolase_6 PF12697.2 CDO78054.1 - 8.1e-14 52.0 1.7 1.4e-13 51.2 0.5 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family CBM_1 PF00734.13 CDO78054.1 - 1.2e-11 44.0 14.3 4.1e-11 42.3 9.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Abhydrolase_1 PF00561.15 CDO78054.1 - 1.5e-08 34.5 0.1 7.4e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDO78054.1 - 0.0012 18.6 0.0 0.0043 16.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CDO78054.1 - 0.33 10.0 0.0 0.48 9.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Na_H_Exchanger PF00999.16 CDO78056.1 - 9.4e-23 80.3 35.6 1.5e-11 43.4 10.7 4.1 4 0 0 4 4 4 4 Sodium/hydrogen exchanger family DUF4231 PF14015.1 CDO78056.1 - 0.014 15.3 2.6 0.014 15.3 1.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Peptidase_S10 PF00450.17 CDO78058.1 - 7.9e-97 325.0 4.0 9.6e-97 324.7 2.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 CDO78058.1 - 0.0071 16.1 0.0 0.021 14.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family GDI PF00996.13 CDO78059.1 - 1.9e-56 191.2 0.0 3.4e-56 190.4 0.0 1.3 2 0 0 2 2 2 1 GDP dissociation inhibitor DUF2638 PF10937.3 CDO78059.1 - 6.2e-15 56.1 0.3 1.7e-14 54.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) NAD_binding_8 PF13450.1 CDO78059.1 - 0.00043 20.2 0.1 0.0015 18.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CDO78059.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDO78059.1 - 0.18 10.5 0.2 0.29 9.9 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain RRM_1 PF00076.17 CDO78060.1 - 3.6e-46 154.6 0.0 1.9e-23 81.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDO78060.1 - 2.1e-31 107.7 0.0 4.3e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDO78060.1 - 3.6e-20 71.5 0.0 5.6e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDO78060.1 - 0.021 14.5 0.0 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Proteasome PF00227.21 CDO78061.1 - 8.5e-47 158.9 0.2 4.5e-46 156.5 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDO78061.1 - 9.3e-15 53.6 0.2 1.7e-14 52.8 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flagellin_N PF00669.15 CDO78061.1 - 0.036 13.8 0.3 0.07 12.9 0.2 1.4 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region NusA_N PF08529.6 CDO78061.1 - 0.26 11.2 1.9 0.45 10.5 0.2 2.0 2 0 0 2 2 2 0 NusA N-terminal domain RNA_pol_Rpb1_5 PF04998.12 CDO78062.1 - 7.1e-97 323.9 0.1 1e-96 323.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CDO78062.1 - 5.4e-89 298.7 0.0 7.9e-89 298.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CDO78062.1 - 9.1e-59 198.1 0.0 2e-58 197.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CDO78062.1 - 1.3e-38 132.2 0.0 2e-37 128.3 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CDO78062.1 - 5.9e-30 103.1 0.0 1.3e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF2786 PF10979.3 CDO78062.1 - 0.0015 18.1 0.5 0.0033 17.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) Zn_Tnp_IS1 PF03811.8 CDO78062.1 - 0.015 14.7 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 InsA N-terminal domain Retrotrans_gag PF03732.12 CDO78063.1 - 0.0019 18.2 0.0 0.0056 16.7 0.0 1.9 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO78063.1 - 0.012 15.5 0.3 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 CDO78064.1 - 1e-05 24.8 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO78064.1 - 0.039 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase UBN2_2 PF14227.1 CDO78066.1 - 1.9e-08 33.9 0.0 2.2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO78066.1 - 4.8e-07 29.5 0.0 6.1e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 CDO78066.1 - 0.00067 19.0 1.1 0.0012 18.3 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CDO78066.1 - 0.015 15.2 5.7 0.023 14.6 4.0 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 CDO78066.1 - 0.035 13.8 2.3 0.062 13.0 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 CDO78067.1 - 2e-13 50.1 0.0 4.8e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 CDO78067.1 - 0.024 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO78067.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 CDO78067.1 - 0.19 11.3 0.5 0.33 10.6 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle RAP1 PF07218.6 CDO78067.1 - 0.4 8.7 5.2 0.53 8.3 3.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-RVT PF13966.1 CDO78068.1 - 9.3e-06 25.8 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase ABC_tran PF00005.22 CDO78071.1 - 4.3e-25 88.5 0.0 7.7e-15 55.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CDO78071.1 - 2.3e-08 34.3 0.0 0.00057 19.9 0.0 2.5 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 CDO78071.1 - 3.4e-05 23.6 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 CDO78071.1 - 0.0012 18.3 0.0 0.0027 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CDO78071.1 - 0.0099 15.8 0.6 5.6 6.9 0.2 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CDO78071.1 - 0.025 14.6 0.2 0.61 10.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 CDO78071.1 - 0.05 12.8 0.3 0.093 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SMC_N PF02463.14 CDO78071.1 - 0.1 11.8 0.0 28 3.8 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 CDO78071.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 CDO78071.1 - 0.23 11.7 0.5 0.4 10.9 0.3 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 CDO78071.1 - 0.34 8.1 0.1 0.48 7.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ribosomal_L23eN PF03939.8 CDO78072.1 - 7.9e-22 77.0 9.7 7.9e-22 77.0 6.7 2.0 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 CDO78072.1 - 2e-20 72.5 1.6 3.6e-20 71.6 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Peptidase_M28 PF04389.12 CDO78073.1 - 2.2e-29 102.4 0.1 4.3e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CDO78073.1 - 0.0023 17.4 0.0 0.027 14.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Transposase_21 PF02992.9 CDO78075.1 - 2.6e-15 56.1 0.0 9e-15 54.3 0.0 1.9 1 1 1 2 2 2 1 Transposase family tnp2 DDE_3 PF13358.1 CDO78075.1 - 9.6e-15 54.5 0.4 1.9e-14 53.6 0.3 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4218 PF13960.1 CDO78075.1 - 0.0022 17.4 0.1 0.0045 16.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) rve PF00665.21 CDO78075.1 - 0.032 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain GST_N_3 PF13417.1 CDO78078.1 - 3.4e-22 78.4 0.0 6.2e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO78078.1 - 8.6e-16 57.7 0.0 1.5e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CDO78078.1 - 2.4e-07 30.6 0.1 4.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDO78078.1 - 4.5e-07 29.6 0.0 7.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CDO78078.1 - 1.5e-06 28.2 0.0 2.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CDO78078.1 - 0.0012 19.3 0.0 0.0054 17.1 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain IR1-M PF12185.3 CDO78078.1 - 0.085 12.5 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain UBN2_2 PF14227.1 CDO78080.1 - 1e-09 37.9 0.0 2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO78080.1 - 7.2e-09 35.3 1.4 3.4e-08 33.1 0.4 2.4 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO78080.1 - 1e-08 34.3 0.4 2.1e-08 33.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 CDO78080.1 - 2.2e-07 30.6 0.0 5.9e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-MYND PF01753.13 CDO78081.1 - 3.4e-10 39.6 12.4 7.8e-10 38.4 8.6 1.7 1 0 0 1 1 1 1 MYND finger RNA_pol_Rpb5_N PF03871.9 CDO78081.1 - 0.086 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain Desulfoferrod_N PF06397.7 CDO78081.1 - 0.22 10.9 2.5 0.66 9.4 1.7 1.8 1 1 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Peptidase_A21 PF03566.8 CDO78083.1 - 0.38 8.8 6.0 0.54 8.2 4.2 1.2 1 0 0 1 1 1 0 Peptidase family A21 Adenylsucc_synt PF00709.16 CDO78084.1 - 3.2e-163 543.3 0.0 3.6e-163 543.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase PCI PF01399.22 CDO78085.1 - 4.6e-17 62.2 0.5 5.6e-17 61.9 0.3 1.0 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 CDO78085.1 - 0.006 16.3 0.2 0.076 12.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Npa1 PF11707.3 CDO78085.1 - 0.038 12.9 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DDRGK PF09756.4 CDO78085.1 - 0.051 12.9 0.1 0.06 12.7 0.1 1.1 1 0 0 1 1 1 0 DDRGK domain T2SG PF08334.6 CDO78085.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G TPR_11 PF13414.1 CDO78085.1 - 0.12 12.0 0.1 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 TPR repeat DUF904 PF06005.7 CDO78087.1 - 2.1 8.6 5.1 5 7.4 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF4218 PF13960.1 CDO78088.1 - 0.00028 20.3 0.1 0.00058 19.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Glyco_hydro_18 PF00704.23 CDO78089.1 - 7.6e-14 51.9 2.2 9.8e-14 51.5 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 CDO78090.1 - 2.9e-06 26.9 0.2 4.1e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LEA_6 PF10714.4 CDO78090.1 - 0.05 13.4 0.4 0.13 12.0 0.3 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 DDE_Tnp_4 PF13359.1 CDO78092.1 - 1.9e-28 99.0 0.0 2.7e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 CDO78092.1 - 3.2e-06 26.8 0.0 2.7e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 CDO78092.1 - 1.4e-05 24.6 0.0 0.00011 21.6 0.0 1.9 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 CDO78092.1 - 0.00014 21.9 0.1 0.0003 20.9 0.1 1.5 1 0 0 1 1 1 1 Transposase DDE domain UVR PF02151.14 CDO78092.1 - 0.31 10.6 2.3 0.63 9.6 1.6 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif Myb_DNA-bind_4 PF13837.1 CDO78093.1 - 2.3e-09 37.2 0.1 4e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO78093.1 - 6.4e-07 29.9 0.1 9.5e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 CDO78093.1 - 4.1e-05 23.3 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO78093.1 - 0.0079 16.2 0.1 0.017 15.2 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myc_N PF01056.13 CDO78093.1 - 0.0087 15.2 1.6 0.016 14.4 1.1 1.4 1 0 0 1 1 1 1 Myc amino-terminal region LAT PF15234.1 CDO78093.1 - 0.019 14.4 1.5 0.029 13.8 1.0 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells Sigma70_ner PF04546.8 CDO78093.1 - 0.045 13.3 6.1 0.034 13.7 3.0 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.7 CDO78093.1 - 0.12 10.3 2.5 0.15 9.9 1.7 1.1 1 0 0 1 1 1 0 Nop14-like family Myb_DNA-binding PF00249.26 CDO78093.1 - 0.13 12.2 0.9 0.37 10.8 0.7 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain DUF2890 PF11081.3 CDO78093.1 - 0.64 10.0 8.3 0.25 11.3 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) RRN3 PF05327.6 CDO78093.1 - 0.81 7.7 2.4 1.1 7.2 1.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.5 CDO78093.1 - 4.2 7.6 11.3 8.2 6.7 7.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HET PF06985.6 CDO78096.1 - 3.6e-21 75.7 0.5 2.5e-17 63.3 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) API5 PF05918.6 CDO78097.1 - 2.2e-11 42.9 0.0 2.2e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 CDO78097.1 - 5.1e-05 23.4 0.7 0.0011 19.2 0.0 3.1 3 1 0 3 3 3 1 HEAT repeats NmrA PF05368.8 CDO78099.1 - 1.8e-09 37.1 0.1 2.5e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CDO78099.1 - 1.3e-08 35.1 0.1 1.5e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CDO78099.1 - 0.0023 18.1 0.1 0.0084 16.4 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CDO78099.1 - 0.004 16.1 0.2 0.0055 15.7 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 CDO78099.1 - 0.0048 15.8 0.1 0.033 13.1 0.1 1.9 1 1 1 2 2 2 1 Male sterility protein TrkA_N PF02254.13 CDO78099.1 - 0.047 13.7 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF1643 PF07799.7 CDO78099.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Epimerase PF01370.16 CDO78100.1 - 6.2e-16 58.5 0.0 1.2e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDO78100.1 - 4e-13 48.7 0.0 6.3e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CDO78100.1 - 5.8e-13 48.3 0.0 1.8e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CDO78100.1 - 1.2e-11 44.9 0.0 3.8e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CDO78100.1 - 6.8e-06 25.1 0.0 1.5e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CDO78100.1 - 1e-05 25.5 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDO78100.1 - 9.6e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 CDO78100.1 - 0.00047 19.4 0.1 0.0021 17.3 0.1 2.0 1 1 1 2 2 2 1 NmrA-like family Dynamin_M PF01031.15 CDO78101.1 - 1.5e-27 96.1 0.0 2.7e-16 59.2 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 CDO78101.1 - 3.1e-26 92.2 0.0 8.3e-26 90.7 0.0 1.8 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 CDO78101.1 - 6.3e-09 35.6 2.5 7.6e-09 35.3 0.4 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CDO78101.1 - 7.9e-05 22.5 0.4 0.0012 18.7 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CDO78101.1 - 0.0015 18.9 0.1 0.0035 17.8 0.1 1.8 1 1 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 CDO78101.1 - 0.0039 17.1 0.1 0.015 15.2 0.1 2.1 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CDO78101.1 - 0.029 14.0 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CDO78101.1 - 0.15 11.5 0.1 0.42 10.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Retrotrans_gag PF03732.12 CDO78103.1 - 2.1e-09 37.3 0.3 3.2e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO78103.1 - 0.00034 20.3 3.6 0.00053 19.7 2.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CDO78103.1 - 0.023 14.3 2.8 0.031 13.9 1.3 1.7 2 0 0 2 2 2 0 Zinc knuckle RVT_2 PF07727.9 CDO78104.1 - 4.9e-25 87.9 0.0 7.8e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO78104.1 - 1.1e-06 28.7 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RD3 PF14473.1 CDO78104.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 RD3 protein rve PF00665.21 CDO78105.1 - 5.2e-21 74.9 0.0 7.6e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDO78105.1 - 0.15 11.5 0.4 0.85 9.1 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain rve PF00665.21 CDO78107.1 - 1.2e-19 70.6 0.0 2.3e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 CDO78107.1 - 2.1e-10 40.1 0.1 4.4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO78107.1 - 6.8e-07 29.0 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO78107.1 - 5.1e-05 23.0 3.5 0.00012 21.8 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.1 CDO78107.1 - 0.0017 17.9 0.1 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_3 PF14244.1 CDO78107.1 - 0.003 17.1 0.0 0.0063 16.0 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type FTP PF07504.8 CDO78107.1 - 0.019 14.4 0.1 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif zf-C4H2 PF10146.4 CDO78107.1 - 1.7 8.6 6.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein Retrotrans_gag PF03732.12 CDO78108.1 - 3.1e-13 49.5 0.0 7.5e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein GMC_oxred_N PF00732.14 CDO78110.1 - 9.1e-55 185.8 0.0 2.1e-53 181.4 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO78110.1 - 7.4e-35 120.3 0.0 1.6e-34 119.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CDO78110.1 - 2.8e-07 29.7 0.1 0.00014 20.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDO78110.1 - 2.8e-05 24.0 0.1 7.6e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CDO78110.1 - 0.00072 18.5 0.3 0.0011 18.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CDO78110.1 - 0.0011 18.1 0.0 0.0026 16.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 CDO78110.1 - 0.0085 14.9 0.7 0.013 14.3 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CDO78110.1 - 0.014 15.7 0.2 0.61 10.5 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDO78110.1 - 0.034 14.0 0.5 0.5 10.2 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CDO78110.1 - 0.041 13.6 0.2 0.13 12.0 0.2 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CDO78110.1 - 0.046 13.7 0.5 3.8 7.5 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDO78110.1 - 0.13 10.7 0.2 0.34 9.3 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.11 CDO78111.1 - 3.7e-24 85.1 32.5 4.6e-24 84.7 22.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF373 PF04123.8 CDO78111.1 - 1.1 8.1 5.2 0.12 11.3 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Methyltransf_25 PF13649.1 CDO78112.1 - 1.1e-06 28.9 0.0 4e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDO78112.1 - 0.0027 17.4 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDO78112.1 - 0.058 13.4 0.0 0.15 12.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 CDO78114.1 - 9.5e-46 156.1 36.3 2.1e-45 154.9 25.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO78114.1 - 9.8e-15 53.7 17.1 1.2e-14 53.4 11.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CDO78114.1 - 2.5e-14 52.7 10.1 2.5e-14 52.7 7.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter B12D PF06522.6 CDO78114.1 - 0.0097 15.5 0.2 0.034 13.8 0.2 2.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit S1FA PF04689.8 CDO78114.1 - 0.026 14.3 0.1 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 DNA binding protein S1FA DUF4097 PF13349.1 CDO78114.1 - 0.81 9.2 9.3 0.64 9.5 1.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4097) DUF202 PF02656.10 CDO78114.1 - 8.8 6.6 15.8 9.2 6.5 0.8 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF202) GMC_oxred_N PF00732.14 CDO78115.1 - 2e-50 171.6 0.0 3.7e-50 170.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO78115.1 - 8.3e-31 107.2 0.0 1.4e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 CDO78115.1 - 8.6e-05 21.6 0.1 0.00013 20.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 CDO78115.1 - 9.8e-05 21.4 0.0 0.00099 18.1 0.0 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDO78115.1 - 0.00015 21.7 0.1 0.00063 19.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CDO78115.1 - 0.0065 15.3 0.4 0.014 14.3 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CDO78115.1 - 0.024 13.1 0.1 0.037 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 CDO78115.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDO78115.1 - 0.092 11.8 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Sulfatase PF00884.18 CDO78116.1 - 0.066 12.3 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Sulfatase OPT PF03169.10 CDO78118.1 - 3.3e-205 683.2 63.0 3.7e-205 683.0 43.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.9 CDO78118.1 - 0.062 13.0 0.4 0.062 13.0 0.3 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) zf-FPG_IleRS PF06827.9 CDO78122.1 - 0.0023 17.5 1.7 0.0073 15.9 1.2 1.8 1 1 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-CHY PF05495.7 CDO78122.1 - 0.0058 16.7 2.8 0.0075 16.4 1.9 1.2 1 0 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.5 CDO78122.1 - 0.012 15.4 4.2 0.019 14.9 2.9 1.2 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 CDO78122.1 - 0.013 15.0 2.4 0.08 12.4 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 CDO78122.1 - 0.025 14.2 2.3 0.035 13.7 1.6 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 CDO78122.1 - 0.033 13.8 0.5 0.04 13.5 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 CDO78122.1 - 0.038 13.9 2.2 0.075 13.0 1.5 1.6 1 1 0 1 1 1 0 zinc-finger zf-RING_5 PF14634.1 CDO78122.1 - 0.038 13.7 2.6 0.056 13.1 1.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain C1_4 PF07975.7 CDO78122.1 - 0.04 13.9 3.4 0.066 13.2 2.3 1.4 1 0 0 1 1 1 0 TFIIH C1-like domain DRP PF06044.7 CDO78122.1 - 0.069 12.1 0.2 0.065 12.2 0.1 1.1 1 0 0 1 1 1 0 Dam-replacing family LIM PF00412.17 CDO78122.1 - 0.069 13.2 4.1 0.093 12.8 2.9 1.2 1 0 0 1 1 1 0 LIM domain zinc_ribbon_4 PF13717.1 CDO78122.1 - 0.076 12.7 5.0 3.7 7.3 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 CDO78122.1 - 0.23 11.3 3.2 0.42 10.4 2.1 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 CDO78122.1 - 0.44 9.8 3.8 1 8.6 2.7 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-C3HC4 PF00097.20 CDO78122.1 - 0.48 10.1 4.4 0.72 9.5 3.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_5 PF13719.1 CDO78122.1 - 0.56 9.8 7.1 4.6 6.9 0.2 2.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 CDO78122.1 - 0.64 10.1 3.6 1.1 9.3 2.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.2 CDO78122.1 - 0.81 9.5 3.6 4.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-DNL PF05180.7 CDO78122.1 - 3.2 7.5 6.7 30 4.4 4.6 2.0 1 1 0 1 1 1 0 DNL zinc finger zf-H2C2_2 PF13465.1 CDO78122.1 - 3.2 8.1 7.5 14 6.2 1.7 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Cys_rich_KTR PF14205.1 CDO78122.1 - 3.7 7.0 6.5 59 3.2 4.5 2.1 1 1 0 1 1 1 0 Cysteine-rich KTR zf-C2H2 PF00096.21 CDO78122.1 - 5.3 7.5 6.4 4.8 7.7 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type MFS_1 PF07690.11 CDO78123.1 - 1.1e-43 149.3 36.4 1.1e-43 149.3 25.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CDO78123.1 - 7.1e-12 44.6 13.4 7.1e-12 44.6 9.3 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter zf-H2C2_2 PF13465.1 CDO78124.1 - 0.032 14.5 0.3 0.08 13.2 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger double domain PLA2_B PF01735.13 CDO78125.1 - 1.3e-20 73.0 0.8 2e-07 29.5 3.0 3.9 3 1 0 3 3 3 3 Lysophospholipase catalytic domain S4 PF01479.20 CDO78126.1 - 9.4e-12 44.1 0.0 1.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 CDO78126.1 - 0.0016 17.9 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 S4 domain CDC45 PF02724.9 CDO78126.1 - 0.0071 14.4 0.2 0.0087 14.1 0.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Tim54 PF11711.3 CDO78126.1 - 1 7.8 6.6 0.075 11.6 1.3 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.9 CDO78126.1 - 5.6 6.9 8.4 41 4.1 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Spc97_Spc98 PF04130.8 CDO78127.1 - 3.3e-123 411.8 0.0 3.9e-123 411.6 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GST_N_3 PF13417.1 CDO78128.1 - 2e-14 53.5 0.0 3.6e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO78128.1 - 3.2e-08 33.4 0.0 6.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO78128.1 - 2.6e-06 27.5 0.0 8.2e-06 25.9 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CDO78128.1 - 0.00017 21.5 0.0 0.0004 20.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 CDO78128.1 - 0.0009 19.0 0.4 0.0025 17.6 0.2 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain rve PF00665.21 CDO78129.1 - 2.3e-13 50.3 0.0 3.1e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain UBN_AB PF14075.1 CDO78130.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.4 3 0 0 3 3 3 0 Ubinuclein conserved middle domain Glypican PF01153.14 CDO78130.1 - 1.6 7.2 8.8 2.8 6.4 2.9 2.1 2 0 0 2 2 2 0 Glypican Zn_clus PF00172.13 CDO78130.1 - 2.2 8.2 12.7 0.071 13.0 4.6 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DTHCT PF08070.6 CDO78130.1 - 2.4 8.8 12.6 14 6.4 0.2 2.6 2 0 0 2 2 2 0 DTHCT (NUC029) region Asp_protease_2 PF13650.1 CDO78131.1 - 0.0014 19.0 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 CDO78131.1 - 0.035 13.6 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease HALZ PF02183.13 CDO78134.1 - 0.029 14.1 0.2 0.054 13.2 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Acetyltransf_1 PF00583.19 CDO78135.1 - 1.3e-05 25.1 0.1 3.1e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CDO78135.1 - 0.0038 17.3 0.0 0.024 14.7 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CDO78135.1 - 0.065 13.4 0.0 0.48 10.6 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CDO78135.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ATP_bind_1 PF03029.12 CDO78136.1 - 1.2e-71 240.9 0.0 1.5e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 CDO78136.1 - 0.069 13.0 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDO78136.1 - 0.13 13.0 7.4 0.056 14.2 1.8 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CDO78136.1 - 0.19 11.6 0.7 1.9 8.4 0.5 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase GST_N_3 PF13417.1 CDO78137.1 - 1.2e-13 51.0 0.0 2.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDO78137.1 - 6.1e-08 32.5 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDO78137.1 - 0.00017 21.7 0.0 0.00059 19.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CDO78137.1 - 0.0099 15.7 0.3 0.02 14.7 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DDE_3 PF13358.1 CDO78138.1 - 1e-25 90.1 0.0 1.6e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CDO78138.1 - 2.7e-10 40.1 2.7 6.2e-07 29.3 0.7 3.3 3 0 0 3 3 3 2 Transposase HTH_38 PF13936.1 CDO78138.1 - 1.7e-07 30.6 0.0 4.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CDO78138.1 - 2.1e-07 30.3 0.3 1.2e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CDO78138.1 - 9.9e-06 25.6 2.6 1.3e-05 25.2 0.6 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 CDO78138.1 - 1.8e-05 24.6 5.8 3.4e-05 23.7 0.0 3.0 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_11 PF08279.7 CDO78138.1 - 0.00021 20.8 0.1 0.0024 17.4 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_IclR PF09339.5 CDO78138.1 - 0.00024 20.6 0.0 0.00069 19.1 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.2 CDO78138.1 - 0.00057 19.4 0.4 0.0026 17.3 0.0 2.1 2 0 0 2 2 2 1 MarR family HTH_Tnp_ISL3 PF13542.1 CDO78138.1 - 0.00089 18.3 0.4 0.01 14.9 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.11 CDO78138.1 - 0.0011 18.2 0.0 0.0028 16.9 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_AraC PF00165.18 CDO78138.1 - 0.0039 16.9 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family rve PF00665.21 CDO78138.1 - 0.0092 16.0 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain GntR PF00392.16 CDO78138.1 - 0.016 14.6 0.1 0.052 13.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.10 CDO78138.1 - 0.021 14.6 0.1 2 8.3 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_24 PF13412.1 CDO78138.1 - 0.024 13.9 0.3 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 CDO78138.1 - 0.026 14.2 0.2 0.074 12.7 0.0 1.9 2 0 0 2 2 1 0 MarR family TrmB PF01978.14 CDO78138.1 - 0.032 13.9 0.0 0.099 12.3 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 CDO78138.1 - 0.044 13.6 1.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.1 CDO78138.1 - 0.044 13.3 1.1 0.27 10.8 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Phage_NinH PF06322.6 CDO78138.1 - 0.21 11.2 1.0 0.41 10.2 0.1 1.9 2 0 0 2 2 2 0 Phage NinH protein SNF2_N PF00176.18 CDO78139.1 - 8.8e-22 77.2 0.1 1.4e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 CDO78139.1 - 7.2e-14 51.6 0.2 3.2e-13 49.5 0.0 2.2 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.1 CDO78139.1 - 0.5 10.1 12.3 0.021 14.5 3.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zinc_ribbon_5 PF13719.1 CDO78141.1 - 0.02 14.4 0.3 0.046 13.2 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CDO78141.1 - 0.025 14.2 0.3 0.062 12.9 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DUF3973 PF13119.1 CDO78141.1 - 0.027 14.4 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) LPAM_2 PF13627.1 CDO78142.1 - 0.67 9.7 0.1 0.67 9.7 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site GCV_T PF01571.16 CDO78143.1 - 4.5e-60 202.6 0.0 5.6e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CDO78143.1 - 8.1e-23 80.2 0.2 1.7e-22 79.2 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pkinase PF00069.20 CDO78144.1 - 0.0063 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CDO78144.1 - 0.045 13.4 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Transposase_21 PF02992.9 CDO78147.1 - 1.4e-15 57.0 0.0 3.2e-15 55.8 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 CDO78147.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) zf-C4_ClpX PF06689.8 CDO78147.1 - 0.27 10.7 1.9 7.3 6.1 0.0 2.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger DUF3435 PF11917.3 CDO78148.1 - 0.13 10.9 1.2 0.24 10.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) BRE1 PF08647.6 CDO78148.1 - 0.34 10.9 5.1 0.11 12.4 1.3 1.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Pkinase PF00069.20 CDO78149.1 - 4.1e-10 39.2 0.0 1e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO78149.1 - 3.8e-05 22.8 0.0 5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Transposase_21 PF02992.9 CDO78151.1 - 2.9e-14 52.7 0.0 4.9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 CDO78151.1 - 0.011 15.1 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Pkinase PF00069.20 CDO78153.1 - 3.6e-10 39.4 0.0 8.8e-10 38.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO78153.1 - 4.1e-05 22.7 0.0 5.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1179 PF06678.6 CDO78155.1 - 0.079 13.2 2.8 0.15 12.4 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1179) DDE_Tnp_4 PF13359.1 CDO78156.1 - 3.8e-22 78.5 0.0 4.7e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 CDO78156.1 - 4.5e-06 26.3 0.0 1.1e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 CDO78156.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.5 1 1 0 1 1 1 0 Plant transposon protein Transposase_21 PF02992.9 CDO78157.1 - 8.2e-16 57.7 0.0 1.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 RVT_1 PF00078.22 CDO78159.1 - 5.3e-23 81.5 0.0 9e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO78159.1 - 2.8e-19 69.3 0.1 9.6e-19 67.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CDO78159.1 - 1.7e-08 34.0 0.0 3.4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 CDO78159.1 - 0.025 14.2 0.1 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain RVP_2 PF08284.6 CDO78159.1 - 0.085 12.7 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease RVT_2 PF07727.9 CDO78159.1 - 0.4 9.6 0.4 0.75 8.7 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) SNF2_N PF00176.18 CDO78161.1 - 5.2e-17 61.5 0.0 9.4e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDO78161.1 - 3.6e-13 49.1 0.1 1.3e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_4 PF13871.1 CDO78161.1 - 0.043 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Helicase_C-like ResIII PF04851.10 CDO78161.1 - 0.31 10.8 0.0 0.89 9.3 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PH_10 PF15411.1 CDO78162.1 - 1.1e-34 119.1 0.0 2e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 CDO78162.1 - 1.9e-28 99.5 0.3 3.6e-28 98.6 0.2 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 CDO78162.1 - 1.2e-17 63.3 0.0 2.6e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.6 CDO78162.1 - 1.6e-12 47.2 0.0 3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin DHH PF01368.15 CDO78163.1 - 1.2e-05 25.0 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 DHH family DUF3904 PF13044.1 CDO78164.1 - 0.053 11.9 0.2 0.086 11.2 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3904) Glyco_hydro_63 PF03200.11 CDO78166.1 - 2.1e-08 32.5 5.6 2e-07 29.3 0.5 3.3 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase Mito_carr PF00153.22 CDO78167.1 - 3.8e-56 186.7 3.0 4.5e-26 90.4 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein RhoGAP PF00620.22 CDO78167.1 - 1.1e-31 109.5 0.0 1.9e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain EPSP_synthase PF00275.15 CDO78167.1 - 0.29 9.5 0.0 0.48 8.8 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HTH_Tnp_Tc5 PF03221.11 CDO78168.1 - 0.041 13.6 0.0 0.18 11.6 0.0 2.1 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Cu-oxidase_3 PF07732.10 CDO78173.1 - 6.8e-39 132.2 0.2 1.4e-37 128.0 0.3 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CDO78173.1 - 7.8e-39 132.3 3.3 1.4e-34 118.6 0.0 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 CDO78173.1 - 9.4e-27 93.8 0.1 1.1e-21 77.4 0.0 3.6 2 1 2 4 4 4 2 Multicopper oxidase RNase_H PF00075.19 CDO78174.1 - 1.1e-13 51.6 0.0 1.9e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 CDO78174.1 - 4e-13 49.2 0.0 6.6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CDO78174.1 - 0.0018 18.5 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase BH3 PF15285.1 CDO78174.1 - 0.091 12.2 0.2 0.3 10.6 0.1 1.9 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Pro-kuma_activ PF09286.6 CDO78176.1 - 3.7e-40 137.2 0.0 6.1e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CDO78176.1 - 0.0039 16.3 0.1 0.0076 15.4 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Amidohydro_3 PF07969.6 CDO78177.1 - 0.0013 18.0 0.3 0.0018 17.5 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family PAT1 PF09770.4 CDO78177.1 - 0.73 8.0 27.7 0.91 7.6 19.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HAUS-augmin3 PF14932.1 CDO78178.1 - 0.18 10.9 0.2 0.3 10.2 0.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 F-box PF00646.28 CDO78179.1 - 3.2e-08 33.0 0.0 6.3e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDO78179.1 - 3.5e-08 33.0 0.0 7.6e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like FBA_3 PF08268.7 CDO78179.1 - 0.0035 17.0 0.1 2.2 8.0 0.0 2.3 2 0 0 2 2 2 2 F-box associated domain Cullin PF00888.17 CDO78180.1 - 6.3e-156 520.3 0.2 9.2e-156 519.8 0.2 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CDO78180.1 - 1.9e-29 101.2 3.1 6.5e-29 99.5 2.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Xpo1 PF08389.7 CDO78180.1 - 6.1e-17 61.9 3.3 6.8e-16 58.4 0.0 4.2 5 1 1 6 6 6 1 Exportin 1-like protein HEAT PF02985.17 CDO78180.1 - 4.7e-05 23.1 1.5 0.02 14.9 0.0 5.2 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 CDO78180.1 - 0.0067 16.6 3.9 0.55 10.5 0.0 4.7 5 0 0 5 5 5 1 HEAT repeats DnaJ PF00226.26 CDO78181.1 - 4.3e-26 90.4 4.5 4.3e-26 90.4 3.1 1.9 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 CDO78181.1 - 9e-23 79.9 0.1 5.6e-22 77.4 0.0 2.2 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CDO78181.1 - 8.9e-17 60.9 16.7 1.5e-16 60.2 11.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CDO78181.1 - 2.3e-05 24.0 3.7 0.043 13.4 0.0 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 CDO78181.1 - 0.011 16.0 6.4 2.4 8.5 1.7 3.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_6 PF14599.1 CDO78181.1 - 0.014 15.1 0.4 0.014 15.1 0.3 2.4 2 0 0 2 2 2 0 Zinc-ribbon A2L_zn_ribbon PF08792.5 CDO78181.1 - 0.17 11.4 10.6 1.6 8.2 0.5 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain DZR PF12773.2 CDO78181.1 - 0.29 10.9 10.0 2.6 7.9 7.5 2.0 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 CDO78181.1 - 1.8 8.6 11.5 21 5.1 0.8 3.8 2 1 2 4 4 4 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 CDO78181.1 - 3.3 7.0 9.3 12 5.3 3.5 2.7 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_3 PF14369.1 CDO78181.1 - 5.1 7.1 12.4 28 4.7 0.0 4.1 3 1 1 4 4 4 0 zinc-finger zf-RING_5 PF14634.1 CDO78181.1 - 7.1 6.4 9.1 5.4 6.8 1.3 2.3 2 0 0 2 2 2 0 zinc-RING finger domain SAP PF02037.22 CDO78184.1 - 0.0003 20.2 0.0 0.00072 19.0 0.0 1.7 1 0 0 1 1 1 1 SAP domain AAA_11 PF13086.1 CDO78184.1 - 0.15 11.5 6.4 0.22 11.0 4.5 1.1 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.6 CDO78184.1 - 0.3 9.7 5.9 0.37 9.4 4.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) AAA_22 PF13401.1 CDO78184.1 - 0.37 10.9 1.5 0.62 10.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF659 PF04937.10 CDO78186.1 - 1.5e-06 27.8 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.9 CDO78186.1 - 3.8e-05 23.2 0.0 8.1e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF772 PF05598.6 CDO78186.1 - 0.04 13.8 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Transposase domain (DUF772) TetR_C_7 PF14246.1 CDO78186.1 - 0.1 12.8 0.1 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal region EHN PF06441.7 CDO78188.1 - 4.5e-35 119.9 0.0 8.6e-35 119.0 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CDO78188.1 - 1.3e-12 48.1 0.5 3.3e-12 46.8 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDO78188.1 - 2.4e-08 33.8 0.0 3.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold GvpG PF05120.7 CDO78188.1 - 0.032 14.0 0.1 0.098 12.4 0.0 1.8 2 0 0 2 2 2 0 Gas vesicle protein G Glycos_transf_3 PF00591.16 CDO78189.1 - 5.1e-60 202.9 0.0 5.9e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain RVT_2 PF07727.9 CDO78191.1 - 7.1e-52 175.8 0.0 1e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO78192.1 - 9.6e-23 80.5 0.0 3e-22 78.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 CDO78192.1 - 1.5e-15 56.8 0.0 3.3e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO78192.1 - 2.7e-11 43.2 0.0 4.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 CDO78192.1 - 2.3e-10 39.9 0.0 5e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_3 PF14244.1 CDO78192.1 - 1.1e-05 25.0 1.2 2.2e-05 24.0 0.8 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 CDO78192.1 - 0.00082 18.8 0.1 0.0033 16.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 CDO78192.1 - 0.17 11.8 6.6 0.59 10.1 4.6 2.0 1 1 0 1 1 1 0 Zinc knuckle DUF3729 PF12526.3 CDO78193.1 - 1.4 10.3 7.4 2.6 9.4 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3729) Stm1_N PF09598.5 CDO78193.1 - 1.4 9.6 6.6 0.63 10.7 2.6 1.9 2 0 0 2 2 2 0 Stm1 Pkinase PF00069.20 CDO78194.1 - 0.097 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 CDO78195.1 - 0.00067 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Rer1 PF03248.8 CDO78196.1 - 1.7e-57 193.8 1.1 3.2e-47 160.3 0.1 2.0 1 1 1 2 2 2 2 Rer1 family Rhabdo_glycop PF00974.13 CDO78196.1 - 0.06 11.5 0.1 0.083 11.1 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein FA_desaturase PF00487.19 CDO78196.1 - 0.68 9.3 4.9 1.2 8.4 3.4 1.3 1 1 0 1 1 1 0 Fatty acid desaturase Pkinase PF00069.20 CDO78197.1 - 0.0012 18.1 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Steroid_dh PF02544.11 CDO78198.1 - 2.5e-30 105.2 6.2 4.9e-21 75.0 4.8 3.0 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CDO78198.1 - 2.2e-07 30.4 1.4 3.7e-06 26.4 1.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) TPR_11 PF13414.1 CDO78199.1 - 5.8e-11 41.8 10.0 1.8e-07 30.6 2.0 3.4 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 CDO78199.1 - 0.0014 18.1 5.9 0.049 13.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH PF00642.19 CDO78199.1 - 0.094 12.4 0.2 0.094 12.4 0.1 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_17 PF13431.1 CDO78199.1 - 0.13 12.5 1.3 2 8.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CDO78199.1 - 3.2 7.8 14.7 1.4 8.9 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RVT_1 PF00078.22 CDO78200.1 - 0.062 12.6 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RIO1 PF01163.17 CDO78200.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CDO78201.1 - 4.1e-13 49.6 0.1 6e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.11 CDO78203.1 - 2.2e-31 108.8 51.9 1.9e-30 105.7 32.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CDO78203.1 - 3.5e-07 28.7 6.8 2.1e-06 26.2 0.1 2.5 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CDO78203.1 - 3.7e-05 22.4 4.1 3.7e-05 22.4 2.9 4.2 2 2 2 5 5 5 3 Sugar (and other) transporter OATP PF03137.15 CDO78203.1 - 0.32 9.0 7.5 0.15 10.0 0.9 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.20 CDO78205.1 - 0.00066 18.8 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CDO78205.1 - 0.012 15.3 1.3 0.035 13.8 0.9 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CDO78205.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MFS_1 PF07690.11 CDO78208.1 - 6e-33 114.0 58.3 8.9e-27 93.7 11.6 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 CDO78208.1 - 0.12 10.4 15.8 0.0077 14.4 6.2 2.3 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 CDO78211.1 - 8.6e-42 143.0 49.9 4.3e-29 101.3 11.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 CDO78211.1 - 0.3 9.2 15.3 0.028 12.6 6.3 2.3 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 CDO78211.1 - 2.5 6.0 12.6 0.014 13.5 0.5 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family BTB PF00651.26 CDO78212.1 - 0.13 12.3 0.0 1 9.3 0.0 2.0 1 1 0 1 1 1 0 BTB/POZ domain RVT_1 PF00078.22 CDO78213.1 - 1.7e-24 86.3 0.0 3.1e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 CDO78213.1 - 4.5e-07 29.8 0.0 8.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CDO78213.1 - 1.2e-06 28.8 0.0 2.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDO78213.1 - 2.6e-06 27.1 0.0 6.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 CDO78213.1 - 0.01 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Ty3 transposon peptidase Retrotrans_gag PF03732.12 CDO78214.1 - 1.2e-14 54.1 0.0 3e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 CDO78214.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO78214.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RAP1 PF07218.6 CDO78214.1 - 0.73 7.8 5.6 0.95 7.4 3.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Clathrin-link PF09268.5 CDO78215.1 - 0.021 13.8 0.1 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Clathrin, heavy-chain linker BSP_II PF05432.6 CDO78215.1 - 0.036 13.3 1.9 0.05 12.8 1.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) rve PF00665.21 CDO78216.1 - 0.00069 19.7 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1330 PF07045.6 CDO78217.1 - 0.012 15.4 0.5 3.5 7.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1330) zf-Di19 PF05605.7 CDO78221.1 - 0.04 14.0 2.6 0.72 10.0 0.2 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Sds3 PF08598.6 CDO78222.1 - 0.79 9.2 5.9 0.5 9.8 2.5 1.7 1 1 1 2 2 2 0 Sds3-like CAP59_mtransfer PF11735.3 CDO78225.1 - 8.2e-60 202.0 0.0 1.2e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Spb1_C PF07780.7 CDO78227.1 - 3.5e-69 232.5 36.1 3.5e-69 232.5 25.0 4.9 4 2 0 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 CDO78227.1 - 1.9e-46 157.5 8.2 1.9e-46 157.5 5.7 6.1 6 1 0 6 6 6 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 CDO78227.1 - 1.2e-33 116.6 0.0 2.9e-33 115.3 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase SLS PF14611.1 CDO78228.1 - 2.1e-07 30.6 0.0 3.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator CCDC66 PF15236.1 CDO78228.1 - 1.4 8.4 6.6 6.9 6.2 0.3 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 66 Sugar_tr PF00083.19 CDO78229.1 - 5.5e-42 143.8 26.1 2.2e-41 141.9 18.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDO78229.1 - 8.2e-15 54.3 36.2 1.3e-08 33.9 11.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF606 PF04657.8 CDO78229.1 - 0.022 14.8 2.1 0.022 14.8 1.4 4.2 4 2 0 4 4 4 0 Protein of unknown function, DUF606 Metallophos_2 PF12850.2 CDO78233.1 - 0.00026 20.8 0.0 0.00079 19.2 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CDO78233.1 - 0.14 11.5 0.5 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase zf-CCCH_2 PF14608.1 CDO78234.1 - 4.6e-11 42.2 34.4 0.00066 19.5 2.5 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type OHCU_decarbox PF09349.5 CDO78235.1 - 0.013 15.7 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 OHCU decarboxylase AAA_16 PF13191.1 CDO78235.1 - 0.077 12.9 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 CDO78236.1 - 6e-38 130.4 0.0 8.5e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDO78236.1 - 6.4e-19 68.0 0.0 9.6e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDO78236.1 - 6.8e-05 21.9 0.0 0.00053 19.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DHHA2 PF02833.9 CDO78237.1 - 2.2e-16 60.2 0.0 3.5e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 CDO78237.1 - 1.5e-14 53.9 0.0 2.6e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 DHH family Transposase_21 PF02992.9 CDO78241.1 - 1.7e-10 40.4 0.0 1.5e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 CDO78241.1 - 0.0043 16.4 0.1 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Transgly PF00912.17 CDO78241.1 - 0.098 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Transglycosylase PHA_gran_rgn PF09650.5 CDO78241.1 - 0.13 12.3 0.1 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Pkinase PF00069.20 CDO78242.1 - 0.0058 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF3106 PF11304.3 CDO78242.1 - 0.12 12.7 0.7 0.24 11.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Pkinase PF00069.20 CDO78244.1 - 0.00093 18.4 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain NACHT PF05729.7 CDO78245.1 - 1.7e-07 31.0 0.0 7.7e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 CDO78245.1 - 6.2e-07 29.6 0.1 4.5e-05 23.5 0.0 3.4 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.1 CDO78245.1 - 1.3e-06 28.4 3.2 1.6e-05 24.9 0.0 3.2 1 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.24 CDO78245.1 - 3.8e-05 23.8 0.1 0.0083 16.3 0.0 3.5 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 CDO78245.1 - 0.00023 20.1 0.0 0.0004 19.3 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 CDO78245.1 - 0.001 18.0 0.0 0.0032 16.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 CDO78245.1 - 0.0051 16.2 0.0 0.015 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain MutS_III PF05192.13 CDO78245.1 - 0.0075 16.0 0.8 0.068 12.9 0.6 2.3 1 1 0 1 1 1 1 MutS domain III AAA_30 PF13604.1 CDO78245.1 - 0.034 13.7 0.0 0.088 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CDO78245.1 - 0.036 13.7 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 CDO78245.1 - 0.036 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 CDO78245.1 - 0.086 13.1 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 CDO78245.1 - 0.087 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.15 CDO78245.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RIO1 PF01163.17 CDO78247.1 - 0.038 13.3 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 RIO1 family UPF0560 PF10577.4 CDO78248.1 - 0.15 10.2 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Chromo PF00385.19 CDO78250.1 - 6.9e-09 35.2 0.0 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CDO78250.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Chromo shadow domain gag_pre-integrs PF13976.1 CDO78252.1 - 1.5e-06 27.7 0.0 2.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Chorion_2 PF03964.10 CDO78252.1 - 0.096 13.2 5.8 0.67 10.5 0.2 3.0 3 0 0 3 3 3 0 Chorion family 2 Dimer_Tnp_hAT PF05699.9 CDO78253.1 - 1.3e-14 53.5 0.0 2.5e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FlxA PF14282.1 CDO78254.1 - 6.2 6.8 10.1 4.7 7.2 0.4 2.4 2 0 0 2 2 2 0 FlxA-like protein TPT PF03151.11 CDO78258.1 - 1.9e-08 34.1 9.7 2.1e-08 33.9 6.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EmrE PF13536.1 CDO78258.1 - 0.0051 16.9 8.0 0.0061 16.7 5.5 1.1 1 0 0 1 1 1 1 Multidrug resistance efflux transporter DUF914 PF06027.7 CDO78258.1 - 0.062 12.1 0.1 0.069 11.9 0.1 1.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) COPI_assoc PF08507.5 CDO78258.1 - 0.066 12.9 0.2 0.079 12.6 0.2 1.2 1 0 0 1 1 1 0 COPI associated protein EamA PF00892.15 CDO78258.1 - 0.23 11.4 8.6 0.27 11.2 6.0 1.1 1 0 0 1 1 1 0 EamA-like transporter family UAA PF08449.6 CDO78258.1 - 0.28 10.0 5.8 0.32 9.8 4.0 1.1 1 0 0 1 1 1 0 UAA transporter family DUF2878 PF11086.3 CDO78258.1 - 0.3 11.0 5.3 0.41 10.6 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2878) DUF3816 PF12822.2 CDO78258.1 - 3.9 7.3 8.8 4.8 7.0 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) p450 PF00067.17 CDO78259.1 - 1.9e-32 112.3 0.0 2.7e-27 95.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 CDO78260.1 - 8.3e-79 265.2 0.0 9.9e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ArfGap PF01412.13 CDO78261.1 - 3.8e-12 46.0 0.1 8.4e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Mre11_DNA_bind PF04152.9 CDO78264.1 - 2e-24 86.4 1.3 3.1e-13 49.9 0.0 3.4 2 1 1 3 3 3 2 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CDO78264.1 - 8.8e-24 84.0 1.0 1.5e-23 83.2 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDO78264.1 - 3.2e-06 27.0 0.0 1.5e-05 24.8 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Ribophorin_II PF05817.9 CDO78264.1 - 0.17 10.0 0.0 0.26 9.4 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II TPT PF03151.11 CDO78265.1 - 4.9e-13 49.0 10.7 4.9e-13 49.0 7.4 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CDO78265.1 - 6.1e-05 23.0 31.8 0.00093 19.2 8.7 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CDO78265.1 - 0.0077 15.1 22.8 0.012 14.5 15.8 1.3 1 0 0 1 1 1 1 UAA transporter family Romo1 PF10247.4 CDO78265.1 - 5.7 7.2 8.4 0.76 10.0 0.3 3.1 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Dynamin_M PF01031.15 CDO78268.1 - 5.6e-14 51.6 0.0 6.2e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 Dynamin central region DDE_3 PF13358.1 CDO78271.1 - 1e-25 90.1 0.0 1.5e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CDO78271.1 - 5.4e-10 39.1 3.7 9.4e-07 28.8 1.1 3.3 3 0 0 3 3 3 2 Transposase HTH_38 PF13936.1 CDO78271.1 - 1.7e-07 30.6 0.0 4.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CDO78271.1 - 2e-07 30.4 0.3 1.2e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CDO78271.1 - 1.7e-05 24.8 3.4 2.3e-05 24.5 1.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 CDO78271.1 - 3.4e-05 23.7 0.0 3.4e-05 23.7 0.0 2.8 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_11 PF08279.7 CDO78271.1 - 0.00021 20.8 0.1 0.0024 17.4 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_IclR PF09339.5 CDO78271.1 - 0.00026 20.5 0.0 0.00069 19.1 0.0 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain Sigma70_r4 PF04545.11 CDO78271.1 - 0.00087 18.5 0.0 0.0028 16.9 0.0 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 CDO78271.1 - 0.001 18.2 0.4 0.01 14.9 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.2 CDO78271.1 - 0.0014 18.2 1.1 0.0026 17.3 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_AraC PF00165.18 CDO78271.1 - 0.0039 16.9 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family rve PF00665.21 CDO78271.1 - 0.0055 16.7 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain GntR PF00392.16 CDO78271.1 - 0.017 14.5 0.0 0.052 13.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_7 PF02796.10 CDO78271.1 - 0.021 14.6 0.1 2 8.3 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_24 PF13412.1 CDO78271.1 - 0.024 14.0 0.3 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 CDO78271.1 - 0.03 14.0 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 MarR family TrmB PF01978.14 CDO78271.1 - 0.035 13.8 0.0 0.099 12.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.1 CDO78271.1 - 0.041 13.4 1.1 0.27 10.8 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_20 PF12840.2 CDO78271.1 - 0.043 13.6 1.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Phage_NinH PF06322.6 CDO78271.1 - 0.21 11.2 1.0 0.41 10.2 0.1 1.9 2 0 0 2 2 2 0 Phage NinH protein Cpn60_TCP1 PF00118.19 CDO78272.1 - 1e-127 426.7 14.3 2.1e-92 310.2 4.2 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family PMT PF02366.13 CDO78273.1 - 1e-78 264.1 14.8 1e-78 264.1 10.2 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CDO78273.1 - 7e-44 149.6 0.5 1.5e-43 148.6 0.3 1.6 1 0 0 1 1 1 1 MIR domain Cyclin_N PF00134.18 CDO78274.1 - 2.6e-08 33.4 0.3 8.1e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CDO78274.1 - 0.37 10.7 5.7 1.4 8.8 1.7 2.7 2 1 0 2 2 2 0 Cyclin, C-terminal domain CoaE PF01121.15 CDO78275.1 - 2.7e-07 30.1 0.0 4.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase Dimer_Tnp_hAT PF05699.9 CDO78277.1 - 4.8e-11 42.1 0.0 1.8e-10 40.2 0.0 2.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region UBN2_2 PF14227.1 CDO78278.1 - 9.4e-15 54.2 0.0 2.7e-14 52.7 0.0 1.7 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO78278.1 - 2.7e-12 46.5 0.0 4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CDO78278.1 - 4.5e-06 26.3 2.7 1e-05 25.1 1.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CDO78278.1 - 7.5e-05 22.1 0.3 0.00016 21.1 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4219 PF13961.1 CDO78278.1 - 0.00012 21.4 0.0 0.00012 21.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 CDO78278.1 - 0.00039 20.0 0.0 0.00065 19.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.1 CDO78278.1 - 0.047 13.4 0.5 0.1 12.3 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 CDO78279.1 - 2.7e-20 72.6 0.0 4.9e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CDO78279.1 - 2.5e-10 40.2 0.1 1.5e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDO78279.1 - 0.023 14.6 0.3 0.05 13.5 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.1 CDO78279.1 - 0.14 12.6 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_2 PF07727.9 CDO78279.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1669 PF07894.7 CDO78279.1 - 0.59 9.2 5.5 0.36 9.9 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1669) Macoilin PF09726.4 CDO78279.1 - 4.8 5.3 6.6 7.4 4.7 4.6 1.2 1 0 0 1 1 1 0 Transmembrane protein RVT_2 PF07727.9 CDO78280.1 - 1.2e-77 260.1 0.0 1.8e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDO78280.1 - 1.9e-17 63.4 0.0 5.5e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 CDO78280.1 - 6.5e-05 22.6 3.5 0.00014 21.5 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.1 CDO78280.1 - 0.003 17.1 0.0 0.0085 15.7 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 CDO78280.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CDO78280.1 - 0.14 11.6 0.0 0.32 10.5 0.0 1.6 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Endonuc-FokI_C PF09254.6 CDO78280.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal UBN2_3 PF14244.1 CDO78281.1 - 6.5e-06 25.7 0.0 0.00029 20.4 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 CDO78281.1 - 0.0037 17.0 0.1 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CDO78281.1 - 0.049 13.1 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF2953 PF11167.3 CDO78282.1 - 0.019 14.8 3.8 0.18 11.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) DUF3538 PF12057.3 CDO78282.1 - 0.041 13.5 0.1 0.12 12.0 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3538) GMC_oxred_N PF00732.14 CDO78283.1 - 5.3e-55 186.6 0.0 7.4e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CDO78283.1 - 1.1e-06 28.9 0.0 2.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 CDO78283.1 - 0.0039 17.1 0.1 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDO78283.1 - 0.012 14.5 0.1 0.19 10.6 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDO78283.1 - 0.025 13.4 0.4 0.045 12.5 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 CDO78283.1 - 0.12 11.2 0.2 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 CDO78283.1 - 0.18 10.8 0.1 0.38 9.8 0.1 1.5 1 0 0 1 1 1 0 Thi4 family F-box-like PF12937.2 CDO78285.1 - 5.3e-09 35.6 0.3 9.9e-09 34.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDO78285.1 - 2.2e-08 33.5 0.5 4.6e-08 32.5 0.3 1.6 1 0 0 1 1 1 1 F-box domain zf-C4H2 PF10146.4 CDO78286.1 - 0.28 11.1 1.7 2.7 7.9 0.1 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein Dimer_Tnp_hAT PF05699.9 CDO78287.1 - 0.0032 17.0 0.0 0.0095 15.5 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SNF2_N PF00176.18 CDO78288.1 - 4.4e-70 235.8 0.0 1.4e-68 230.9 0.0 2.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDO78288.1 - 6.2e-14 51.6 0.0 2.1e-13 49.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CDO78288.1 - 7.8e-08 31.4 0.0 2.7e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-RING_UBOX PF13445.1 CDO78288.1 - 0.0088 15.7 0.0 0.028 14.1 0.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger AA_permease_2 PF13520.1 CDO78289.1 - 3.1e-63 213.7 32.7 4.1e-63 213.4 22.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CDO78289.1 - 1.2e-14 53.5 30.4 1.6e-14 53.1 21.0 1.0 1 0 0 1 1 1 1 Amino acid permease RabGAP-TBC PF00566.13 CDO78290.1 - 3.9e-31 108.1 0.0 5.5e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.12 CDO78290.1 - 0.0073 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain RVT_2 PF07727.9 CDO78291.1 - 6.9e-05 21.9 0.0 9.5e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.1 CDO78293.1 - 3.8e-22 78.5 0.0 4.7e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 CDO78293.1 - 4.5e-06 26.3 0.0 1.1e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 CDO78293.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.5 1 1 0 1 1 1 0 Plant transposon protein Myb_DNA-bind_4 PF13837.1 CDO78294.1 - 1.2e-05 25.3 0.2 5e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 CDO78294.1 - 0.0001 22.8 0.1 0.00022 21.8 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDO78294.1 - 0.028 14.5 0.2 1.8 8.7 0.0 2.6 2 1 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CDO78294.1 - 0.048 13.7 0.3 0.31 11.1 0.2 2.3 1 1 0 1 1 1 0 Myb-like DNA-binding domain DUF1179 PF06678.6 CDO78294.1 - 0.5 10.6 0.0 0.5 10.6 0.0 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1179) Tektin PF03148.9 CDO78295.1 - 0.0048 15.4 0.5 0.054 12.0 0.1 2.1 2 0 0 2 2 2 1 Tektin family AAA_16 PF13191.1 CDO78295.1 - 0.014 15.3 0.4 0.16 11.9 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain AAA_19 PF13245.1 CDO78295.1 - 0.015 15.0 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CDO78295.1 - 0.017 15.2 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CDO78295.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain UBN2_2 PF14227.1 CDO78296.1 - 2.3e-09 36.8 0.0 4.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CDO78296.1 - 5.3e-09 35.7 1.4 2.8e-08 33.4 0.4 2.4 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 CDO78296.1 - 1e-08 34.3 0.4 2.1e-08 33.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 CDO78296.1 - 7.4e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DDHD PF02862.12 CDO78296.1 - 0.63 9.7 5.0 1.1 9.0 3.5 1.3 1 0 0 1 1 1 0 DDHD domain